Science.gov

Sample records for applied systems analysis

  1. Sneak analysis applied to process systems

    NASA Astrophysics Data System (ADS)

    Whetton, Cris

    Traditional safety analyses, such as HAZOP, FMEA, FTA, and MORT, are less than effective at identifying hazards resulting from incorrect 'flow' - whether this be flow of information, actions, electric current, or even the literal flow of process fluids. Sneak Analysis (SA) has existed since the mid nineteen-seventies as a means of identifying such conditions in electric circuits; in which area, it is usually known as Sneak Circuit Analysis (SCA). This paper extends the ideas of Sneak Circuit Analysis to a general method of Sneak Analysis applied to process plant. The methods of SA attempt to capitalize on previous work in the electrical field by first producing a pseudo-electrical analog of the process and then analyzing the analog by the existing techniques of SCA, supplemented by some additional rules and clues specific to processes. The SA method is not intended to replace any existing method of safety analysis; instead, it is intended to supplement such techniques as HAZOP and FMEA by providing systematic procedures for the identification of a class of potential problems which are not well covered by any other method.

  2. Applying Systems Analysis to Program Failure in Organizations.

    ERIC Educational Resources Information Center

    Holt, Margaret E.; And Others

    1986-01-01

    Certain systems analysis techniques can be applied to examinations of program failure in continuing education to locate weaknesses in planning and implementing stages. Questions to guide an analysis and various procedures are recommended. Twelve issues that contribute to failures or discontinuations are identified. (Author/MLW)

  3. Probabilistic Analysis Techniques Applied to Complex Spacecraft Power System Modeling

    NASA Technical Reports Server (NTRS)

    Hojnicki, Jeffrey S.; Rusick, Jeffrey J.

    2005-01-01

    Electric power system performance predictions are critical to spacecraft, such as the International Space Station (ISS), to ensure that sufficient power is available to support all the spacecraft s power needs. In the case of the ISS power system, analyses to date have been deterministic, meaning that each analysis produces a single-valued result for power capability because of the complexity and large size of the model. As a result, the deterministic ISS analyses did not account for the sensitivity of the power capability to uncertainties in model input variables. Over the last 10 years, the NASA Glenn Research Center has developed advanced, computationally fast, probabilistic analysis techniques and successfully applied them to large (thousands of nodes) complex structural analysis models. These same techniques were recently applied to large, complex ISS power system models. This new application enables probabilistic power analyses that account for input uncertainties and produce results that include variations caused by these uncertainties. Specifically, N&R Engineering, under contract to NASA, integrated these advanced probabilistic techniques with Glenn s internationally recognized ISS power system model, System Power Analysis for Capability Evaluation (SPACE).

  4. Systems design analysis applied to launch vehicle configuration

    NASA Technical Reports Server (NTRS)

    Ryan, R.; Verderaime, V.

    1993-01-01

    As emphasis shifts from optimum-performance aerospace systems to least lift-cycle costs, systems designs must seek, adapt, and innovate cost improvement techniques in design through operations. The systems design process of concept, definition, and design was assessed for the types and flow of total quality management techniques that may be applicable in a launch vehicle systems design analysis. Techniques discussed are task ordering, quality leverage, concurrent engineering, Pareto's principle, robustness, quality function deployment, criteria, and others. These cost oriented techniques are as applicable to aerospace systems design analysis as to any large commercial system.

  5. Applying an Activity System to Online Collaborative Group Work Analysis

    ERIC Educational Resources Information Center

    Choi, Hyungshin; Kang, Myunghee

    2010-01-01

    This study determines whether an activity system provides a systematic framework to analyse collaborative group work. Using an activity system as a unit of analysis, the research examined learner behaviours, conflicting factors and facilitating factors while students engaged in collaborative work via asynchronous computer-mediated communication.…

  6. Dynamical systems analysis applied to working memory data.

    PubMed

    Gasimova, Fidan; Robitzsch, Alexander; Wilhelm, Oliver; Boker, Steven M; Hu, Yueqin; Hülür, Gizem

    2014-01-01

    In the present paper we investigate weekly fluctuations in the working memory capacity (WMC) assessed over a period of 2 years. We use dynamical system analysis, specifically a second order linear differential equation, to model weekly variability in WMC in a sample of 112 9th graders. In our longitudinal data we use a B-spline imputation method to deal with missing data. The results show a significant negative frequency parameter in the data, indicating a cyclical pattern in weekly memory updating performance across time. We use a multilevel modeling approach to capture individual differences in model parameters and find that a higher initial performance level and a slower improvement at the MU task is associated with a slower frequency of oscillation. Additionally, we conduct a simulation study examining the analysis procedure's performance using different numbers of B-spline knots and values of time delay embedding dimensions. Results show that the number of knots in the B-spline imputation influence accuracy more than the number of embedding dimensions.

  7. Grounding system analysis in transients programs applying electromagnetic field approach

    SciTech Connect

    Heimbach, M.; Grcev, L.D.

    1997-01-01

    Lightning protection studies of substations and power systems require knowledge of the dynamic behavior of large grounding grids during electromagnetic transients. This paper presents strategies which allow to incorporate complex grounding structures computed using a rigorous electromagnetic model in transients programs. A novel technique for rational function representation of frequency-dependent grounding system impedances in the EMTP is described. An arbitrary number of feeding points can be modeled as mutual coupling is taken into account. Overvoltages throughout electrical power systems and the transient ground potential rise in the surroundings of grounding structures can be computed.

  8. Experiences with Probabilistic Analysis Applied to Controlled Systems

    NASA Technical Reports Server (NTRS)

    Kenny, Sean P.; Giesy, Daniel P.

    2004-01-01

    This paper presents a semi-analytic method for computing frequency dependent means, variances, and failure probabilities for arbitrarily large-order closed-loop dynamical systems possessing a single uncertain parameter or with multiple highly correlated uncertain parameters. The approach will be shown to not suffer from the same computational challenges associated with computing failure probabilities using conventional FORM/SORM techniques. The approach is demonstrated by computing the probabilistic frequency domain performance of an optimal feed-forward disturbance rejection scheme.

  9. System Analysis Applied to Autonomy: Application to High-Altitude Long-Endurance Remotely Operated Aircraft

    NASA Technical Reports Server (NTRS)

    Young, Larry A.; Yetter, Jeffrey A.; Guynn, Mark D.

    2006-01-01

    Maturation of intelligent systems technologies and their incorporation into aerial platforms are dictating the development of new analysis tools and incorporation of such tools into existing system analysis methodologies in order to fully capture the trade-offs of autonomy on vehicle and mission success. A first-order "system analysis of autonomy" methodology is outlined in this paper. Further, this analysis methodology is subsequently applied to notional high-altitude long-endurance (HALE) aerial vehicle missions.

  10. Applying reliability analysis to design electric power systems for More-electric aircraft

    NASA Astrophysics Data System (ADS)

    Zhang, Baozhu

    The More-Electric Aircraft (MEA) is a type of aircraft that replaces conventional hydraulic and pneumatic systems with electrically powered components. These changes have significantly challenged the aircraft electric power system design. This thesis investigates how reliability analysis can be applied to automatically generate system topologies for the MEA electric power system. We first use a traditional method of reliability block diagrams to analyze the reliability level on different system topologies. We next propose a new methodology in which system topologies, constrained by a set reliability level, are automatically generated. The path-set method is used for analysis. Finally, we interface these sets of system topologies with control synthesis tools to automatically create correct-by-construction control logic for the electric power system.

  11. System Analysis Applied to Autonomy: Application to Human-Rated Lunar/Mars Landers

    NASA Technical Reports Server (NTRS)

    Young, Larry A.

    2006-01-01

    System analysis is an essential technical discipline for the modern design of spacecraft and their associated missions. Specifically, system analysis is a powerful aid in identifying and prioritizing the required technologies needed for mission and/or vehicle development efforts. Maturation of intelligent systems technologies, and their incorporation into spacecraft systems, are dictating the development of new analysis tools, and incorporation of such tools into existing system analysis methodologies, in order to fully capture the trade-offs of autonomy on vehicle and mission success. A "system analysis of autonomy" methodology will be outlined and applied to a set of notional human-rated lunar/Mars lander missions toward answering these questions: 1. what is the optimum level of vehicle autonomy and intelligence required? and 2. what are the specific attributes of an autonomous system implementation essential for a given surface lander mission/application in order to maximize mission success? Future human-rated lunar/Mars landers, though nominally under the control of their crew, will, nonetheless, be highly automated systems. These automated systems will range from mission/flight control functions, to vehicle health monitoring and prognostication, to life-support and other "housekeeping" functions. The optimum degree of autonomy afforded to these spacecraft systems/functions has profound implications from an exploration system architecture standpoint.

  12. System Sensitivity Analysis Applied to the Conceptual Design of a Dual-Fuel Rocket SSTO

    NASA Technical Reports Server (NTRS)

    Olds, John R.

    1994-01-01

    This paper reports the results of initial efforts to apply the System Sensitivity Analysis (SSA) optimization method to the conceptual design of a single-stage-to-orbit (SSTO) launch vehicle. SSA is an efficient, calculus-based MDO technique for generating sensitivity derivatives in a highly multidisciplinary design environment. The method has been successfully applied to conceptual aircraft design and has been proven to have advantages over traditional direct optimization methods. The method is applied to the optimization of an advanced, piloted SSTO design similar to vehicles currently being analyzed by NASA as possible replacements for the Space Shuttle. Powered by a derivative of the Russian RD-701 rocket engine, the vehicle employs a combination of hydrocarbon, hydrogen, and oxygen propellants. Three primary disciplines are included in the design - propulsion, performance, and weights & sizing. A complete, converged vehicle analysis depends on the use of three standalone conceptual analysis computer codes. Efforts to minimize vehicle dry (empty) weight are reported in this paper. The problem consists of six system-level design variables and one system-level constraint. Using SSA in a 'manual' fashion to generate gradient information, six system-level iterations were performed from each of two different starting points. The results showed a good pattern of convergence for both starting points. A discussion of the advantages and disadvantages of the method, possible areas of improvement, and future work is included.

  13. Success Factors of European Syndromic Surveillance Systems: A Worked Example of Applying Qualitative Comparative Analysis

    PubMed Central

    Ziemann, Alexandra; Fouillet, Anne; Brand, Helmut; Krafft, Thomas

    2016-01-01

    Introduction Syndromic surveillance aims at augmenting traditional public health surveillance with timely information. To gain a head start, it mainly analyses existing data such as from web searches or patient records. Despite the setup of many syndromic surveillance systems, there is still much doubt about the benefit of the approach. There are diverse interactions between performance indicators such as timeliness and various system characteristics. This makes the performance assessment of syndromic surveillance systems a complex endeavour. We assessed if the comparison of several syndromic surveillance systems through Qualitative Comparative Analysis helps to evaluate performance and identify key success factors. Materials and Methods We compiled case-based, mixed data on performance and characteristics of 19 syndromic surveillance systems in Europe from scientific and grey literature and from site visits. We identified success factors by applying crisp-set Qualitative Comparative Analysis. We focused on two main areas of syndromic surveillance application: seasonal influenza surveillance and situational awareness during different types of potentially health threatening events. Results We found that syndromic surveillance systems might detect the onset or peak of seasonal influenza earlier if they analyse non-clinical data sources. Timely situational awareness during different types of events is supported by an automated syndromic surveillance system capable of analysing multiple syndromes. To our surprise, the analysis of multiple data sources was no key success factor for situational awareness. Conclusions We suggest to consider these key success factors when designing or further developing syndromic surveillance systems. Qualitative Comparative Analysis helped interpreting complex, mixed data on small-N cases and resulted in concrete and practically relevant findings. PMID:27182731

  14. Biomolecular filters for improved separation of output signals in enzyme logic systems applied to biomedical analysis.

    PubMed

    Halámek, Jan; Zhou, Jian; Halámková, Lenka; Bocharova, Vera; Privman, Vladimir; Wang, Joseph; Katz, Evgeny

    2011-11-15

    Biomolecular logic systems processing biochemical input signals and producing "digital" outputs in the form of YES/NO were developed for analysis of physiological conditions characteristic of liver injury, soft tissue injury, and abdominal trauma. Injury biomarkers were used as input signals for activating the logic systems. Their normal physiological concentrations were defined as logic-0 level, while their pathologically elevated concentrations were defined as logic-1 values. Since the input concentrations applied as logic 0 and 1 values were not sufficiently different, the output signals being at low and high values (0, 1 outputs) were separated with a short gap making their discrimination difficult. Coupled enzymatic reactions functioning as a biomolecular signal processing system with a built-in filter property were developed. The filter process involves a partial back-conversion of the optical-output-signal-yielding product, but only at its low concentrations, thus allowing the proper discrimination between 0 and 1 output values.

  15. Applied Behavior Analysis

    ERIC Educational Resources Information Center

    Szapacs, Cindy

    2006-01-01

    Teaching strategies that work for typically developing children often do not work for those diagnosed with an autism spectrum disorder. However, teaching strategies that work for children with autism do work for typically developing children. In this article, the author explains how the principles and concepts of Applied Behavior Analysis can be…

  16. Model-Based Systems Engineering With the Architecture Analysis and Design Language (AADL) Applied to NASA Mission Operations

    NASA Technical Reports Server (NTRS)

    Munoz Fernandez, Michela Miche

    2014-01-01

    The potential of Model Model Systems Engineering (MBSE) using the Architecture Analysis and Design Language (AADL) applied to space systems will be described. AADL modeling is applicable to real-time embedded systems- the types of systems NASA builds. A case study with the Juno mission to Jupiter showcases how this work would enable future missions to benefit from using these models throughout their life cycle from design to flight operations.

  17. Applying STAMP in Accident Analysis

    NASA Technical Reports Server (NTRS)

    Leveson, Nancy; Daouk, Mirna; Dulac, Nicolas; Marais, Karen

    2003-01-01

    Accident models play a critical role in accident investigation and analysis. Most traditional models are based on an underlying chain of events. These models, however, have serious limitations when used for complex, socio-technical systems. Previously, Leveson proposed a new accident model (STAMP) based on system theory. In STAMP, the basic concept is not an event but a constraint. This paper shows how STAMP can be applied to accident analysis using three different views or models of the accident process and proposes a notation for describing this process.

  18. Evaluation Applied to Reliability Analysis of Reconfigurable, Highly Reliable, Fault-Tolerant, Computing Systems for Avionics

    NASA Technical Reports Server (NTRS)

    Migneault, G. E.

    1979-01-01

    Emulation techniques are proposed as a solution to a difficulty arising in the analysis of the reliability of highly reliable computer systems for future commercial aircraft. The difficulty, viz., the lack of credible precision in reliability estimates obtained by analytical modeling techniques are established. The difficulty is shown to be an unavoidable consequence of: (1) a high reliability requirement so demanding as to make system evaluation by use testing infeasible, (2) a complex system design technique, fault tolerance, (3) system reliability dominated by errors due to flaws in the system definition, and (4) elaborate analytical modeling techniques whose precision outputs are quite sensitive to errors of approximation in their input data. The technique of emulation is described, indicating how its input is a simple description of the logical structure of a system and its output is the consequent behavior. The use of emulation techniques is discussed for pseudo-testing systems to evaluate bounds on the parameter values needed for the analytical techniques.

  19. A new multi criteria classification approach in a multi agent system applied to SEEG analysis.

    PubMed

    Kinié, A; Ndiaye, M; Montois, J J; Jacquelet, Y

    2007-01-01

    This work is focused on the study of the organization of the SEEG signals during epileptic seizures with multi-agent system approach. This approach is based on cooperative mechanisms of auto-organization at the micro level and of emergence of a global function at the macro level. In order to evaluate this approach we propose a distributed collaborative approach for the classification of the interesting signals. This new multi-criteria classification method is able to provide a relevant brain area structures organisation and to bring out epileptogenic networks elements. The method is compared to another classification approach a fuzzy classification and gives better results when applied to SEEG signals.

  20. Topological data analysis (TDA) applied to reveal pedogenetic principles of European topsoil system.

    PubMed

    Savic, Aleksandar; Toth, Gergely; Duponchel, Ludovic

    2017-05-15

    Recent developments in applied mathematics are bringing new tools that are capable to synthesize knowledge in various disciplines, and help in finding hidden relationships between variables. One such technique is topological data analysis (TDA), a fusion of classical exploration techniques such as principal component analysis (PCA), and a topological point of view applied to clustering of results. Various phenomena have already received new interpretations thanks to TDA, from the proper choice of sport teams to cancer treatments. For the first time, this technique has been applied in soil science, to show the interaction between physical and chemical soil attributes and main soil-forming factors, such as climate and land use. The topsoil data set of the Land Use/Land Cover Area Frame survey (LUCAS) was used as a comprehensive database that consists of approximately 20,000 samples, each described by 12 physical and chemical parameters. After the application of TDA, results obtained were cross-checked against known grouping parameters including five types of land cover, nine types of climate and the organic carbon content of soil. Some of the grouping characteristics observed using standard approaches were confirmed by TDA (e.g., organic carbon content) but novel subtle relationships (e.g., magnitude of anthropogenic effect in soil formation), were discovered as well. The importance of this finding is that TDA is a unique mathematical technique capable of extracting complex relations hidden in soil science data sets, giving the opportunity to see the influence of physicochemical, biotic and abiotic factors on topsoil formation through fresh eyes.

  1. Energy analysis of facade-integrated photovoltaic systems applied to UAE commercial buildings

    SciTech Connect

    Radhi, Hassan

    2010-12-15

    Developments in the design and manufacture of photovoltaic cells have recently been a growing concern in the UAE. At present, the embodied energy pay-back time (EPBT) is the criterion used for comparing the viability of such technology against other forms. However, the impact of PV technology on the thermal performance of buildings is not considered at the time of EPBT estimation. If additional energy savings gained over the PV system life are also included, the total EPBT could be shorter. This paper explores the variation of the total energy of building integrated photovoltaic systems (BiPV) as a wall cladding system applied to the UAE commercial sector and shows that the ratio between PV output and saving in energy due to PV panels is within the range of 1:3-1:4. The result indicates that for the southern and western facades in the UAE, the embodied energy pay-back time for photovoltaic system is within the range of 12-13 years. When reductions in operational energy are considered, the pay-back time is reduced to 3.0-3.2 years. This study comes to the conclusion that the reduction in operational energy due to PV panels represents an important factor in the estimation of EPBT. (author)

  2. Multi-attribute criteria applied to electric generation energy system analysis LDRD.

    SciTech Connect

    Kuswa, Glenn W.; Tsao, Jeffrey Yeenien; Drennen, Thomas E.; Zuffranieri, Jason V.; Paananen, Orman Henrie; Jones, Scott A.; Ortner, Juergen G.; Brewer, Jeffrey D.; Valdez, Maximo M.

    2005-10-01

    This report began with a Laboratory-Directed Research and Development (LDRD) project to improve Sandia National Laboratories multidisciplinary capabilities in energy systems analysis. The aim is to understand how various electricity generating options can best serve needs in the United States. The initial product is documented in a series of white papers that span a broad range of topics, including the successes and failures of past modeling studies, sustainability, oil dependence, energy security, and nuclear power. Summaries of these projects are included here. These projects have provided a background and discussion framework for the Energy Systems Analysis LDRD team to carry out an inter-comparison of many of the commonly available electric power sources in present use, comparisons of those options, and efforts needed to realize progress towards those options. A computer aid has been developed to compare various options based on cost and other attributes such as technological, social, and policy constraints. The Energy Systems Analysis team has developed a multi-criteria framework that will allow comparison of energy options with a set of metrics that can be used across all technologies. This report discusses several evaluation techniques and introduces the set of criteria developed for this LDRD.

  3. A new multi criteria classification approach in a multi agent system applied to SEEG analysis

    PubMed Central

    Kinie, Abel; Ndiaye, Mamadou Lamine L.; Montois, Jean-Jacques; Jacquelet, Yann

    2007-01-01

    This work is focused on the study of the organization of the SEEG signals during epileptic seizures with multi-agent system approach. This approach is based on cooperative mechanisms of auto-organization at the micro level and of emergence of a global function at the macro level. In order to evaluate this approach we propose a distributed collaborative approach for the classification of the interesting signals. This new multi-criteria classification method is able to provide a relevant brain area structures organisation and to bring out epileptogenic networks elements. The method is compared to another classification approach a fuzzy classification and gives better results when applied to SEEG signals. PMID:18002381

  4. Applied Surface Analysis Workshop.

    DTIC Science & Technology

    1979-10-01

    field of surface analysis attended the Workshop. The list of participants follows. 5! A, I Charles Anderson Albert L. Botkin Case Western Reserve...Louis, MO 63166 University of Dayton 300 College Park Richard Chase Dayton, OH 45469 Case Western Reserve University University Circle Brian E. P...Dayton, OH 45469 300 College Park Dayton, OH 45469 Richard W. Hoffman Case Western Reserve University Martin Kordesch Cleveland, OH 44106 Case Western

  5. Analysis and Design of International Emission Trading Markets Applying System Dynamics Techniques

    NASA Astrophysics Data System (ADS)

    Hu, Bo; Pickl, Stefan

    2010-11-01

    The design and analysis of international emission trading markets is an important actual challenge. Time-discrete models are needed to understand and optimize these procedures. We give an introduction into this scientific area and present actual modeling approaches. Furthermore, we develop a model which is embedded in a holistic problem solution. Measures for energy efficiency are characterized. The economic time-discrete "cap-and-trade" mechanism is influenced by various underlying anticipatory effects. With a systematic dynamic approach the effects can be examined. First numerical results show that fair international emissions trading can only be conducted with the use of protective export duties. Furthermore a comparatively high price which evokes emission reduction inevitably has an inhibiting effect on economic growth according to our model. As it always has been expected it is not without difficulty to find a balance between economic growth and emission reduction. It can be anticipated using our System Dynamics model simulation that substantial changes must be taken place before international emissions trading markets can contribute to global GHG emissions mitigation.

  6. Enhancing the Effectiveness of Significant Event Analysis: Exploring Personal Impact and Applying Systems Thinking in Primary Care

    PubMed Central

    McNaughton, Elaine; Bruce, David; Holly, Deirdre; Forrest, Eleanor; Macleod, Marion; Kennedy, Susan; Power, Ailsa; Toppin, Denis; Black, Irene; Pooley, Janet; Taylor, Audrey; Swanson, Vivien; Kelly, Moya; Ferguson, Julie; Stirling, Suzanne; Wakeling, Judy; Inglis, Angela; McKay, John; Sargeant, Joan

    2016-01-01

    Introduction: Significant event analysis (SEA) is well established in many primary care settings but can be poorly implemented. Reasons include the emotional impact on clinicians and limited knowledge of systems thinking in establishing why events happen and formulating improvements. To enhance SEA effectiveness, we developed and tested “guiding tools” based on human factors principles. Methods: Mixed-methods development of guiding tools (Personal Booklet—to help with emotional demands and apply a human factors analysis at the individual level; Desk Pad—to guide a team-based systems analysis; and a written Report Format) by a multiprofessional “expert” group and testing with Scottish primary care practitioners who submitted completed enhanced SEA reports. Evaluation data were collected through questionnaire, telephone interviews, and thematic analysis of SEA reports. Results: Overall, 149/240 care practitioners tested the guiding tools and submitted completed SEA reports (62.1%). Reported understanding of how to undertake SEA improved postintervention (P < .001), while most agreed that the Personal Booklet was practical (88/123, 71.5%) and relevant to dealing with related emotions (93/123, 75.6%). The Desk Pad tool helped focus the SEA on systems issues (85/123, 69.1%), while most found the Report Format clear (94/123, 76.4%) and would recommend it (88/123, 71.5%). Most SEA reports adopted a systems approach to analyses (125/149, 83.9%), care improvement (74/149, 49.7), or planned actions (42/149, 28.2%). Discussion: Applying human factors principles to SEA potentially enables care teams to gain a systems-based understanding of why things go wrong, which may help with related emotional demands and with more effective learning and improvement. PMID:27583996

  7. Hazard analysis and critical control point systems applied to public health risks: the example of seafood.

    PubMed

    Williams, R A; Zorn, D J

    1997-08-01

    The authors describe the way in which the two components of risk analysis--risk assessment and risk management--can be used in conjunction with the hazard analysis and critical control points concept to determine the allocation of resources at potential critical control points. This approach is examined in the context of risks to human health associated with seafood, and in particular with regard to ciguatera poisoning.

  8. A Sensitivity Analysis of the Kalman Filter as Applied to an Inertial Navigation System

    DTIC Science & Technology

    1982-06-01

    4 _ * i i i i i i ........ ..T TABLE OF CONTENTS Page I. INTRODUCTION ------------------------------------------- 10 II. MODELS AND ESTIMATION...OF STABILITY --------------------------------------- 19 III. DYNAMIC AND MEASUREMENT SYSTEM MODELS ----------------------- 20 A. REFERENCE AXIS SYSTEM...21 2. Lateral Motion ---------------------------------- 21 C. MODEL DYNAMICS ------------------------------------- 22 1. Longitudinal Motion

  9. Matrix effects in applying mono- and polyclonal ELISA systems to the analysis of weathered oils in contaminated soil.

    PubMed

    Pollard, S J T; Farmer, J G; Knight, D M; Young, P J

    2002-01-01

    Commercial mono- and polyclonal enzyme-linked immunosorbent assay (ELISA) systems were applied to the on-site analysis of weathered hydrocarbon-contaminated soils at a former integrated steelworks. Comparisons were made between concentrations of solvent extractable matter (SEM) determined gravimetrically by Soxhlet (dichloromethane) extraction and those estimated immunologically by ELISA determination over a concentration range of 2000-330,000 mg SEM/kg soil dry weight. Both ELISA systems tinder-reported for the more weathered soil samples. Results suggest this is due to matrix effects in the sample rather than any inherent bias in the ELISA systems and it is concluded that, for weathered hydrocarbons typical of steelworks and coke production sites, the use of ELISA requires careful consideration as a field technique. Consideration of the target analyte relative to the composition of the hydrocarbon waste encountered appears critical.

  10. A novel image processing and measurement system applied to quantitative analysis of simulated tooth root canal shape

    NASA Astrophysics Data System (ADS)

    Yong, Tao; Yong, Wei; Jin, Guofan; Gao, Xuejun

    2005-02-01

    Dental pulp is located in root canal of tooth. To modern root canal therapy, "Root canal preparation" is the main means to debride dental pulp infection. The shape of root canal will be changed after preparation, so, when assessing the preparation instruments and techniques, the root canal shaping ability especially the apical offset is very important factor. In this paper, a novel digital image processing and measurement system is designed and applied to quantitative analysis of simulated canal shape. By image pretreatment, feature extraction, registration and fusion, the variation of the root canals' characteristics (before and after preparation) can be accurately compared and measured, so as to assess the shaping ability of instruments. When the scanning resolution is 1200dpi or higher, the registration and measurement precision of the system can achieve 0.021mm or higher. The performance of the system is tested by a series of simulated root canals and stainless steel K-files.

  11. Core Logistics Capability Policy Applied to USAF Combat Aircraft Avionics Software: A Systems Engineering Analysis

    DTIC Science & Technology

    2010-06-01

    PROJECT Presented to the Faculty Department of Systems and Engineering Management Graduate School of Engineering and Management Air Force...a light grey box around the definitions. This table, a fit-for-purpose architecture product , is loosely based on the DoD Architecture Framework ...synopsis of ISO/IEC 12207, Raghu Singh of the Federal Aviation Administration states “Whenever a software product needs modifications, the development

  12. Global positioning system network analysis with phase ambiguity resolution applied to crustal deformation studies in California

    NASA Technical Reports Server (NTRS)

    Dong, Da-Nan; Bock, Yehuda

    1989-01-01

    An efficient algorithm is developed for multisession adjustment of GPS data with simultaneous orbit determination and ambiguity resolution. Application of the algorithm to the analysis of data from a five-year campaign in progress in southern and central California to monitor tectonic motions using observations by GPS satellites, demonstrates improvements in estimates of station position and satellite orbits when the phase ambiguities are resolved. Most of the phase ambiguities in the GPS network were resolved, particularly for all the baselines of geophysical interest in California.

  13. Applying ABC Analysis to the Navy’s Inventory Management System

    DTIC Science & Technology

    2014-09-01

    AUTHOR(S) Benjamin May 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Postgraduate School Monterey, CA 93943-5000 8. PERFORMING...may not nec trates a typi entage of in areto Diagr as well as e ) analysis. gorization managemen states that t total numb The law ca entory mana...lue than th mn criterion the importa ows the res e calculated ty. on, & Dorai lue assignm 92, p. 74). er based on inventory ca g “criticali could be

  14. Output-Based Adaptive Meshing Applied to Space Launch System Booster Separation Analysis

    NASA Technical Reports Server (NTRS)

    Dalle, Derek J.; Rogers, Stuart E.

    2015-01-01

    This paper presents details of Computational Fluid Dynamic (CFD) simulations of the Space Launch System during solid-rocket booster separation using the Cart3D inviscid code with comparisons to Overflow viscous CFD results and a wind tunnel test performed at NASA Langley Research Center's Unitary PlanWind Tunnel. The Space Launch System (SLS) launch vehicle includes two solid-rocket boosters that burn out before the primary core stage and thus must be discarded during the ascent trajectory. The main challenges for creating an aerodynamic database for this separation event are the large number of basis variables (including orientation of the core, relative position and orientation of the boosters, and rocket thrust levels) and the complex flow caused by the booster separation motors. The solid-rocket boosters are modified from their form when used with the Space Shuttle Launch Vehicle, which has a rich flight history. However, the differences between the SLS core and the Space Shuttle External Tank result in the boosters separating with much narrower clearances, and so reducing aerodynamic uncertainty is necessary to clear the integrated system for flight. This paper discusses an approach that has been developed to analyze about 6000 wind tunnel simulations and 5000 flight vehicle simulations using Cart3D in adaptive-meshing mode. In addition, a discussion is presented of Overflow viscous CFD runs used for uncertainty quantification. Finally, the article presents lessons learned and improvements that will be implemented in future separation databases.

  15. Comparing Waste-to-Energy technologies by applying energy system analysis.

    PubMed

    Münster, Marie; Lund, Henrik

    2010-07-01

    Even when policies of waste prevention, re-use and recycling are prioritised, a fraction of waste will still be left which can be used for energy recovery. This article asks the question: How to utilise waste for energy in the best way seen from an energy system perspective? Eight different Waste-to-Energy technologies are compared with a focus on fuel efficiency, CO(2) reductions and costs. The comparison is carried out by conducting detailed energy system analyses of the present as well as a potential future Danish energy system with a large share of combined heat and power as well as wind power. The study shows potential of using waste for the production of transport fuels. Biogas and thermal gasification technologies are hence interesting alternatives to waste incineration and it is recommended to support the use of biogas based on manure and organic waste. It is also recommended to support research into gasification of waste without the addition of coal and biomass. Together the two solutions may contribute to alternate use of one third of the waste which is currently incinerated. The remaining fractions should still be incinerated with priority to combined heat and power plants with high electric efficiency.

  16. Women in applied behavior analysis

    PubMed Central

    McSweeney, Frances K.; Donahoe, Patricia; Swindell, Samantha

    2000-01-01

    The status of women in applied behavior analysis was examined by comparing the participation of women in the Journal of Applied Behavior Analysis (JABA) to their participation in three similar journals. For all journals, the percentage of articles with at least one female author, the percentage of authors who are female, and the percentage of articles with a female first author increased from 1978 to 1997. Participation by women in JABA was equal to or greater than participation by women in the comparison journals. However, women appeared as authors on papers in special sections of Behavior Modification substantially more often when the editor was female than when the editor was male. In addition, female membership on the editorial boards of JABA, Behavior Modification, and Behaviour Research and Therapy failed to increase from 1978 to 1997. We conclude that a “glass ceiling” reduces the participation of women at the highest levels of applied behavior analysis and related fields. PMID:22478351

  17. Mechanism analysis of Magnetohydrodynamic heat shield system and optimization of externally applied magnetic field

    NASA Astrophysics Data System (ADS)

    Li, Kai; Liu, Jun; Liu, Weiqiang

    2017-04-01

    As a novel thermal protection technique for hypersonic vehicles, Magnetohydrodynamic (MHD) heat shield system has been proved to be of great intrinsic value in the hypersonic field. In order to analyze the thermal protection mechanisms of such a system, a physical model is constructed for analyzing the effect of the Lorentz force components in the counter and normal directions. With a series of numerical simulations, the dominating Lorentz force components are analyzed for the MHD heat flux mitigation in different regions of a typical reentry vehicle. Then, a novel magnetic field with variable included angle between magnetic induction line and streamline is designed, which significantly improves the performance of MHD thermal protection in the stagnation and shoulder areas. After that, the relationships between MHD shock control and MHD thermal protection are investigated, based on which the magnetic field above is secondarily optimized obtaining better performances of both shock control and thermal protection. Results show that the MHD thermal protection is mainly determined by the Lorentz force's effect on the boundary layer. From the stagnation to the shoulder region, the flow deceleration effect of the counter-flow component is weakened while the flow deflection effect of the normal component is enhanced. Moreover, there is no obviously positive correlation between the MHD shock control and thermal protection. But once a good Lorentz force's effect on the boundary layer is guaranteed, the thermal protection performance can be further improved with an enlarged shock stand-off distance by strengthening the counter-flow Lorentz force right after shock.

  18. Advanced Behavioral Applications in Schools: A Review of R. Douglas Greer's "Designing Teaching Strategies: An Applied Behavior Analysis Systems Approach"

    ERIC Educational Resources Information Center

    Moxley, Roy A.

    2004-01-01

    R. Douglas Greer's "Designing Teaching Strategies" is an important book directed to advanced students in applied behavior analysis for classrooms. This review presents some of the striking features of the Comprehensive Applied Behavior Analysis to Schooling (CABAS[R]) program and the individualized instruction that the book advances. These include…

  19. NextGen Brain Microdialysis: Applying Modern Metabolomics Technology to the Analysis of Extracellular Fluid in the Central Nervous System

    PubMed Central

    Kao, Chi-Ya; Anderzhanova, Elmira; Asara, John M.; Wotjak, Carsten T.; Turck, Christoph W.

    2015-01-01

    Microdialysis is a powerful method for in vivo neurochemical analyses. It allows fluid sampling in a dynamic manner in specific brain regions over an extended period of time. A particular focus has been the neurochemical analysis of extracellular fluids to explore central nervous system functions. Brain microdialysis recovers neurotransmitters, low-molecular-weight neuromodulators and neuropeptides of special interest when studying behavior and drug effects. Other small molecules, such as central metabolites, are typically not assessed despite their potential to yield important information related to brain metabolism and activity in selected brain regions. We have implemented a liquid chromatography online mass spectrometry metabolomics platform for an expanded analysis of mouse brain microdialysates. The method is sensitive and delivers information for a far greater number of analytes than commonly used electrochemical and fluorescent detection or biochemical assays. The metabolomics platform was applied to the analysis of microdialysates in a foot shock-induced mouse model of posttraumatic stress disorder (PTSD). The rich metabolite data information was then used to delineate affected prefrontal molecular pathways that reflect individual susceptibility for developing PTSD-like symptoms. We demonstrate that hypothesis-free metabolomics can be adapted to the analysis of microdialysates for the discovery of small molecules with functional significance. PMID:27602357

  20. Frequency Domain Analysis of Beat-Less Control Method for Converter-Inverter Driving Systems Applied to AC Electric Cars

    NASA Astrophysics Data System (ADS)

    Kimura, Akira

    In inverter-converter driving systems for AC electric cars, the DC input voltage of an inverter contains a ripple component with a frequency that is twice as high as the line voltage frequency, because of a single-phase converter. The ripple component of the inverter input voltage causes pulsations on torques and currents of driving motors. To decrease the pulsations, a beat-less control method, which modifies a slip frequency depending on the ripple component, is applied to the inverter control. In the present paper, the beat-less control method was analyzed in the frequency domain. In the first step of the analysis, transfer functions, which revealed the relationship among the ripple component of the inverter input voltage, the slip frequency, the motor torque pulsation and the current pulsation, were derived with a synchronous rotating model of induction motors. An analysis model of the beat-less control method was then constructed using the transfer functions. The optimal setting of the control method was obtained according to the analysis model. The transfer functions and the analysis model were verified through simulations.

  1. Simulating Nationwide Pandemics: Applying the Multi-scale Epidemiologic Simulation and Analysis System to Human Infectious Diseases

    SciTech Connect

    Dombroski, M; Melius, C; Edmunds, T; Banks, L E; Bates, T; Wheeler, R

    2008-09-24

    This study uses the Multi-scale Epidemiologic Simulation and Analysis (MESA) system developed for foreign animal diseases to assess consequences of nationwide human infectious disease outbreaks. A literature review identified the state of the art in both small-scale regional models and large-scale nationwide models and characterized key aspects of a nationwide epidemiological model. The MESA system offers computational advantages over existing epidemiological models and enables a broader array of stochastic analyses of model runs to be conducted because of those computational advantages. However, it has only been demonstrated on foreign animal diseases. This paper applied the MESA modeling methodology to human epidemiology. The methodology divided 2000 US Census data at the census tract level into school-bound children, work-bound workers, elderly, and stay at home individuals. The model simulated mixing among these groups by incorporating schools, workplaces, households, and long-distance travel via airports. A baseline scenario with fixed input parameters was run for a nationwide influenza outbreak using relatively simple social distancing countermeasures. Analysis from the baseline scenario showed one of three possible results: (1) the outbreak burned itself out before it had a chance to spread regionally, (2) the outbreak spread regionally and lasted a relatively long time, although constrained geography enabled it to eventually be contained without affecting a disproportionately large number of people, or (3) the outbreak spread through air travel and lasted a long time with unconstrained geography, becoming a nationwide pandemic. These results are consistent with empirical influenza outbreak data. The results showed that simply scaling up a regional small-scale model is unlikely to account for all the complex variables and their interactions involved in a nationwide outbreak. There are several limitations of the methodology that should be explored in future

  2. Advanced behavioral applications in schools: A review of R. Douglas Greer's designing teaching strategies: An applied behavior analysis systems approach

    PubMed Central

    Moxley, Roy A.

    2004-01-01

    R. Douglas Greer1s Designing Teaching Strategies is an important book directed to advanced students in applied behavior analysis for classrooms. This review presents some of the striking features of the Comprehensive Applied Behavior Analysis to Schooling (CABAS®) program and the individualized instruction that the book advances. These include its instruction in literacy, its use of graphing, and its flexibility in systematic organization. Although its readability could be improved, this book has much to recommend it in an approach that has acquired an international following. PMID:22477295

  3. Applied mathematics of chaotic systems

    SciTech Connect

    Jen, E.; Alber, M.; Camassa, R.; Choi, W.; Crutchfield, J.; Holm, D.; Kovacic, G.; Marsden, J.

    1996-07-01

    This is the final report of a three-year, Laboratory-Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). The objectives of the project were to develop new mathematical techniques for describing chaotic systems and for reexpressing them in forms that can be solved analytically and computationally. The authors focused on global bifurcation analysis of rigid body motion in an ideal incompressible fluid and on an analytical technique for the exact solution of nonlinear cellular automata. For rigid-body motion, they investigated a new completely integrable partial differential equation (PDE) representing model motion of fronts in nematic crystals and studied perturbations of the integrable PDE. For cellular automata with multiple domain structures, the work has included: (1) identification of the associated set of conserved quantities for each type of domain; (2) use of the conserved quantities to construct isomorphism between the nonlinear system and a linear template; and (3) use of exact solvability methods to characterize detailed structure of equilibrium states and to derive bounds for maximal transience times.

  4. Functional analysis, a resilience improvement tool applied to a waste management system - application to the "household waste management chain"

    NASA Astrophysics Data System (ADS)

    Beraud, H.; Barroca, B.; Hubert, G.

    2012-12-01

    A waste management system plays a leading role in the capacity of an area to restart after flooding, as their impact on post-crisis management can be very considerable. Improving resilience, i.e. enabling it to maintain or recover acceptable operating levels after flooding is primordial. To achieve this, we must understand how the system works for bringing any potential dysfunctions to light and taking preventive measures. Functional analysis has been used for understanding the complexity of this type of system. The purpose of this article is to show the interest behind this type of method and the limits in its use for improving resilience of waste management system as well as other urban technical systems1, by means of theoretical modelling and its application on a study site. 1In a systemic vision of the city, urban technical systems combine all the user service systems that are essential for the city to operate (electricity, water supplies, transport, sewerage, etc.). These systems are generally organised in the form of networks (Coutard, 2010; CERTU, 2005).

  5. Electrochemical analysis of chloramphenicol using boron-doped diamond electrode applied to a flow-injection system.

    PubMed

    Chuanuwatanakul, Suchada; Chailapakul, Orawon; Motomizu, Shoji

    2008-04-01

    The electrochemical properties of chloramphenicol at a boron-doped diamond thin-film (BDD) electrode were studied using cyclic voltammetry. The highest current response of chloramphenicol was obtained with phosphate buffer, pH 6 (0.1 M) in 1% ethanol. The relationship between the concentration of chloramphenicol and the current response was linear over the range of 0.1-10 mM (R2=0.9990). The amount of chloramphenicol was analyzed by flow-injection analysis. A thin-layer flow cell equipped with a BDD electrode was used as an amperometric detector, and experiments were carried out at -0.7 V (vs. Ag/AgCl). The linear relationship between the current response and the concentration of chloramphenicol in the range of 0.1-50 microM (R2=0.9948) and the limit of detection of 0.03 microM (S/N=3) were obtained. This method has been successfully applied to the determination of chloramphenicol in sterile eye drops and milk sample by the standard addition method. The average recoveries of chloramphenicol in eye drops were 98.0%, and the average recoveries of chloramphenicol from spiked milk were 93.9-103%.

  6. Economic impacts of bio-refinery and resource cascading systems: an applied general equilibrium analysis for Poland.

    PubMed

    Ignaciuk, Adriana M; Sanders, Johan

    2007-12-01

    Due to more stringent energy and climate policies, it is expected that many traditional chemicals will be replaced by their biomass-based substitutes, bio-chemicals. These innovations, however, can influence land allocation since the demand for land dedicated to specific crops might increase. Moreover, it can have an influence on traditional agricultural production. In this paper, we use an applied general equilibrium framework, in which we include two different bio-refinery processes and incorporate so-called cascading mechanisms. The bio-refinery processes use grass, as one of the major inputs, to produce bio-nylon and propane-diol (1,3PDO) to substitute currently produced fossil fuel-based nylon and ethane-diol. We examine the impact of specific climate policies on the bioelectricity share in total electricity production, land allocation, and production quantities and prices of selected commodities. The novel technologies become competitive, with an increased stringency of climate policies. This switch, however, does not induce a higher share of bioelectricity. The cascade does stimulate the production of bioelectricity, but it induces more of a shift in inputs in the bioelectricity sector (from biomass to the cascaded bio-nylon and 1, 3PDO) than an increase in production level of bioelectricity. We conclude that dedicated biomass crops will remain the main option for bioelectricity production: the contribution of the biomass systems remains limited. Moreover, the bioelectricity sector looses a competition for land for biomass production with bio-refineries.

  7. Comparative analysis of the possibility of applying low-melting metals with the capillary-porous system in tokamak conditions

    NASA Astrophysics Data System (ADS)

    Lyublinski, I. E.; Vertkov, A. V.; Semenov, V. V.

    2016-12-01

    The use of capillary-porous systems (CPSs) with liquid Li, Ga, and Sn is considered as an alternative for solving the problem of creating plasma-facing elements (PFEs) of the fusion neutron source (FNS) and the DEMO-type reactor. The main advantages of CPSs with liquid metal compared with hard materials are their stability with respect to the degradation of properties in tokamak conditions and capability of surface self-restoration. The evaluation of applicability of liquid metals is performed on the basis of the analysis of their physical and chemical properties, the interaction with the tokamak plasma, and constructive and process features of in-vessel elements with CPSs implementing the application of these metals in a tokamak. It is shown that the upper limit of the PFE working temperature for all low-melting metals under consideration lies in the range of 550-600°C. The decisive factor for PFEs with Li is the limitation on the admissible atomic flux into plasma, while for those with Ga and Sn it is the corrosion resistance of construction materials. The upper limit of thermal loads in the steady-state operating mode for the considered promising PFE design with the use of Li, Ga, and Sn is close to 18-20 MW/m2. It is seen from the analysis that the use of metals with a low equilibrium vapor pressure of (Ga, Sn) gives no gain in extension of the region of admissible working temperatures of PFEs. However, with respect to the totality of properties, the possibility of implementing the self-restoration and stabilization effect of the liquid surface, the influence on the plasma discharge parameters, and the ability to protect the PFE surface in conditions of plasma perturbations and disruption, lithium is the most attractive liquid metal to create CPS-based PFEs for the tokamak.

  8. Reachability Analysis Applied to Space Situational Awareness

    NASA Astrophysics Data System (ADS)

    Holzinger, M.; Scheeres, D.

    Several existing and emerging applications of Space Situational Awareness (SSA) relate directly to spacecraft Rendezvous, Proximity Operations, and Docking (RPOD) and Formation / Cluster Flight (FCF). When multiple Resident Space Ob jects (RSOs) are in vicinity of one another with appreciable periods between observations, correlating new RSO tracks to previously known objects becomes a non-trivial problem. A particularly difficult sub-problem is seen when long breaks in observations are coupled with continuous, low- thrust maneuvers. Reachability theory, directly related to optimal control theory, can compute contiguous reachability sets for known or estimated control authority and can support such RSO search and correlation efforts in both ground and on-board settings. Reachability analysis can also directly estimate the minimum control authority of a given RSO. For RPOD and FCF applications, emerging mission concepts such as fractionation drastically increase system complexity of on-board autonomous fault management systems. Reachability theory, as applied to SSA in RPOD and FCF applications, can involve correlation of nearby RSO observations, control authority estimation, and sensor track re-acquisition. Additional uses of reachability analysis are formation reconfiguration, worst-case passive safety, and propulsion failure modes such as a "stuck" thruster. Existing reachability theory is applied to RPOD and FCF regimes. An optimal control policy is developed to maximize the reachability set and optimal control law discontinuities (switching) are examined. The Clohessy-Wiltshire linearized equations of motion are normalized to accentuate relative control authority for spacecraft propulsion systems at both Low Earth Orbit (LEO) and Geostationary Earth Orbit (GEO). Several examples with traditional and low thrust propulsion systems in LEO and GEO are explored to illustrate the effects of relative control authority on the time-varying reachability set surface. Both

  9. A Systematic Comprehensive Computational Model for Stake Estimation in Mission Assurance: Applying Cyber Security Econometrics System (CSES) to Mission Assurance Analysis Protocol (MAAP)

    SciTech Connect

    Abercrombie, Robert K; Sheldon, Frederick T; Grimaila, Michael R

    2010-01-01

    In earlier works, we presented a computational infrastructure that allows an analyst to estimate the security of a system in terms of the loss that each stakeholder stands to sustain as a result of security breakdowns. In this paper, we discuss how this infrastructure can be used in the subject domain of mission assurance as defined as the full life-cycle engineering process to identify and mitigate design, production, test, and field support deficiencies of mission success. We address the opportunity to apply the Cyberspace Security Econometrics System (CSES) to Carnegie Mellon University and Software Engineering Institute s Mission Assurance Analysis Protocol (MAAP) in this context.

  10. The basic importance of applied behavior analysis

    PubMed Central

    Epling, W. Frank; Pierce, W. David

    1986-01-01

    We argue that applied behavior analysis is relevant to basic research. Modification studies, and a broad range of investigations that focus on the precipitating and maintaining conditions of socially significant human behavior, have basic importance. Applied behavior analysis may aid basic researchers in the design of externally valid experiments and thereby enhance the theoretical significance of basic research for understanding human behavior. Applied research with humans, directed at culturally-important problems, will help to propagate the science of human behavior. Such a science will also be furthered by analogue experiments that model socially important behavior. Analytical-applied studies and analogue experiments are forms of applied behavior analysis that could suggest new environment-behavior relationships. These relationships could lead to basic research and principles that further the prediction, control, and understanding of behavior. PMID:22478650

  11. 2012 International Conference on Medical Physics and Biomedical Engineering Thermal Economic Analysis on LiBr Refrigeration -Heat Pump System Applied in CCHP System

    NASA Astrophysics Data System (ADS)

    Zhang, CuiZhen; Yang, Mo; Lu, Mei; Zhu, Jiaxian; Xu, Wendong

    LiBr refrigeration cooling water contains a lot of low-temperature heat source, can use this part of the heat source heat boiler feed water. This paper introduced LiBr refrigeration - heat pump system which recovery heat of the LiBr refrigeration cooling water by heat pump system to heat the feed water of boiler. Hot economic analysis on the system has been performed based on the experimental data. Results show that LiBr refrigeration-heat pump system brings 26.6 percent decrease in primary energy rate consumption comparing with the combined heat and power production system(CHP) and separate generation of cold;

  12. Applied Behavior Analysis and Statistical Process Control?

    ERIC Educational Resources Information Center

    Hopkins, B. L.

    1995-01-01

    Incorporating statistical process control (SPC) methods into applied behavior analysis is discussed. It is claimed that SPC methods would likely reduce applied behavior analysts' intimate contacts with problems and would likely yield poor treatment and research decisions. Cases and data presented by Pfadt and Wheeler (1995) are cited as examples.…

  13. On differentiation in applied behavior analysis

    PubMed Central

    Fawcett, Stephen B.

    1985-01-01

    Distinct types of activity in the field of applied behavior analysis are noted and discussed. Four metaphorical types of activity are considered: prospecting, farming, building, and guiding. Prospecting consists of time-limited exploration of a variety of beaviors, populations, or settings. Farming consists of producing new behaviors in the same setting using independent variables provided by the researchers or normally available in the setting. Building consists of combining procedural elements to create new programs or systems or to rehabilitate aspects of existing programs. Guiding involves pointing out connections between the principles of human behavior and the problems, populations, settings, and procedures with which researchers are (or could be) working. Advantages of each sphere are noted, and benefits of this division of labor to the field as a whole are discussed. PMID:22478631

  14. Stability Analysis of Finite Difference Approximations to Hyperbolic Systems,and Problems in Applied and Computational Matrix and Operator Theory

    DTIC Science & Technology

    1990-12-07

    Technology, Haifa, 1968. 45 10. Bhatia , Rajendra , Perturbation Bounds for Matrix Eigenvalues, Pitman Research Notes in Mathematics, H. Brezis, R. G. Douglas...is currently in press in the SIAM Journal of Matrix Analysis . The proof sheets have been corrected and returned to the editor during the period of this...appear. [3] R. A. Horn and C. R. Johnson, Matrix Analysis , Cambridge University Press, New York, 1985. 141 M. Marcus and N. Khan, A note on the

  15. Applied Behavior Analysis in Flying Training Research.

    DTIC Science & Technology

    1980-01-01

    often referred to as behavior modification ) which promotes improvements in human learning through an analysis of the contingencies surrounding a...Company, in press. Bandura, A. Principles of behavior modification . New York: Holt, Rinehart & Winston, 1969. Bostow, D.E., & Bailey, J.S. Modification of...tutors for kindergarten children. Journal of Applied Behavior Analysis, 1974, 7, 223-232. Kazdin, A.E. Behavior modification in applied settings

  16. System planning analysis applied to OTEC: initial cases by Florida Power Corporation. Task II report No. FC-5237-2

    SciTech Connect

    1980-03-01

    The objective of the task was to exercise the FPC system planning methodology on: (1) Base Case, 10 year generation expansion plan with coal plants providing base load expansion, and (2) same, but 400 MW of OTEC substituting for coal burning units with equal resultant system reliability. OTEC inputs were based on reasonable economic projections of direct capital cost and O and M costs for first-generation large commercial plants. OTEC inputs discussed in Section 2. The Base Case conditions for FPC system planning methodology involved base load coal fueled additions during the 1980's and early 1990's. The first trial runs of the PROMOD system planning model substituted OTEC for 400 MW purchases of coal generated power during 1988-1989 and then 400 MW coal capacity thereafter. Result showed higher system reliability than Base Case runs. Reruns with greater coal fueled capacity displacement showed that OTEC could substitute for 400 MW purchases in 1988-1989 and replace the 800 MW coal unit scheduled for 1990 to yield equivalent system reliability. However, a 1995 unit would need to be moved to 1994. Production costing computer model runs were used as input to Corporate Model to examine corporate financial impact. Present value of total revenue requirements were primary indication of relative competitiveness between Base Case and OTEC. Results show present value of total revenue requirements unfavorable to OTEC as compared to coal units. The disparity was in excess of the allowable range for possible consideration.

  17. Caldwell University's Department of Applied Behavior Analysis.

    PubMed

    Reeve, Kenneth F; Reeve, Sharon A

    2016-05-01

    Since 2004, faculty members at Caldwell University have developed three successful graduate programs in Applied Behavior Analysis (i.e., PhD, MA, non-degree programs), increased program faculty from two to six members, developed and operated an on-campus autism center, and begun a stand-alone Applied Behavior Analysis Department. This paper outlines a number of strategies used to advance these initiatives, including those associated with an extensive public relations campaign. We also outline challenges that have limited our programs' growth. These strategies, along with a consideration of potential challenges, might prove useful in guiding academicians who are interested in starting their own programs in behavior analysis.

  18. Hydrogeochemical variables regionalization--applying cluster analysis for a seasonal evolution model from an estuarine system affected by AMD.

    PubMed

    Grande, J A; Carro, B; Borrego, J; de la Torre, M L; Valente, T; Santisteban, M

    2013-04-15

    This study describes the spatial evolution of the hydrogeochemical parameters which characterise a strongly affected estuary by Acid Mine Drainage (AMD). The studied estuarine system receives AMD from the Iberian Pyrite Belt (SW Spain) and, simultaneously, is affected by the presence of an industrial chemical complex. Water sampling was performed in the year of 2008, comprising four sampling campaigns, in order to represent seasonality. The results show how the estuary can be divided into three areas of different behaviour in response to hydrogeochemical variables concentrations that define each sampling stations: on one hand, an area dominated by tidal influence; in the opposite end there is a second area including the points located in the two rivers headwaters that are not influenced by seawater; finally there is the area that can be defined as mixing zone. These areas are moved along the hydrological year due to seasonal chemical variations.

  19. Thermodynamic Laws Applied to Economic Systems

    ERIC Educational Resources Information Center

    González, José Villacís

    2009-01-01

    Economic activity in its different manifestations--production, exchange, consumption and, particularly, information on quantities and prices--generates and transfers energy. As a result, we can apply to it the basic laws of thermodynamics. These laws are applicable within a system, i.e., in a country or between systems and countries. To these…

  20. System Applies Polymer Powder To Filament Tow

    NASA Technical Reports Server (NTRS)

    Baucom, Robert M.; Snoha, John J.; Marchello, Joseph M.

    1993-01-01

    Polymer powder applied uniformly and in continuous manner. Powder-coating system applies dry polymer powder to continuous fiber tow. Unique filament-spreading technique, combined with precise control of tension on fibers in system, ensures uniform application of polymer powder to web of spread filaments. Fiber tows impregnated with dry polymer powders ("towpregs") produced for preform-weaving and composite-material-molding applications. System and process valuable to prepreg industry, for production of flexible filament-windable tows and high-temperature polymer prepregs.

  1. Defining applied behavior analysis: An historical analogy

    PubMed Central

    Deitz, Samuel M.

    1982-01-01

    This article examines two criteria for a definition of applied behavior analysis. The criteria are derived from a 19th century attempt to establish medicine as a scientific field. The first criterion, experimental determinism, specifies the methodological boundaries of an experimental science. The second criterion, philosophic doubt, clarifies the tentative nature of facts and theories derived from those facts. Practices which will advance the science of behavior are commented upon within each criteria. To conclude, the problems of a 19th century form of empiricism in medicine are related to current practices in applied behavior analysis. PMID:22478557

  2. Goals Analysis Procedure Guidelines for Applying the Goals Analysis Process

    NASA Technical Reports Server (NTRS)

    Motley, Albert E., III

    2000-01-01

    One of the key elements to successful project management is the establishment of the "right set of requirements", requirements that reflect the true customer needs and are consistent with the strategic goals and objectives of the participating organizations. A viable set of requirements implies that each individual requirement is a necessary element in satisfying the stated goals and that the entire set of requirements, taken as a whole, is sufficient to satisfy the stated goals. Unfortunately, it is the author's experience that during project formulation phases' many of the Systems Engineering customers do not conduct a rigorous analysis of the goals and objectives that drive the system requirements. As a result, the Systems Engineer is often provided with requirements that are vague, incomplete, and internally inconsistent. To complicate matters, most systems development methodologies assume that the customer provides unambiguous, comprehensive and concise requirements. This paper describes the specific steps of a Goals Analysis process applied by Systems Engineers at the NASA Langley Research Center during the formulation of requirements for research projects. The objective of Goals Analysis is to identify and explore all of the influencing factors that ultimately drive the system's requirements.

  3. Applied Behavior Analysis: Beyond Discrete Trial Teaching

    ERIC Educational Resources Information Center

    Steege, Mark W.; Mace, F. Charles; Perry, Lora; Longenecker, Harold

    2007-01-01

    We discuss the problem of autism-specific special education programs representing themselves as Applied Behavior Analysis (ABA) programs when the only ABA intervention employed is Discrete Trial Teaching (DTT), and often for limited portions of the school day. Although DTT has many advantages to recommend its use, it is not well suited to teach…

  4. Positive Behavior Support and Applied Behavior Analysis

    ERIC Educational Resources Information Center

    Johnston, J. M.; Foxx, R. M.; Jacobson, J. W.; Green, G.; Mulick, J. A.

    2006-01-01

    This article reviews the origins and characteristics of the positive behavior support (PBS) movement and examines those features in the context of the field of applied behavior analysis (ABA). We raise a number of concerns about PBS as an approach to delivery of behavioral services and its impact on how ABA is viewed by those in human services. We…

  5. Applied Behavior Analysis as Technological Science.

    ERIC Educational Resources Information Center

    Iwata, Brian A.

    1991-01-01

    To the extent that applied behavior analysis represents a scientific and practical approach to the study of behavior, its technological character is essential. The most serious problem evident in the field is not that the research being done is too technical but that more good research of all types is needed. (JDD)

  6. Reachability Analysis Applied to Space Situational Awareness

    DTIC Science & Technology

    2009-09-01

    12:207-242. [15] L. S. Breger, G. Inalhan, M. Tillerson, J. P. How, “Cooperative spacecraft Formation Flying: Model Predictive Control With Open And...applying them to the nonlinear relative orbit equations of motion, which are appropriate both for general SSA and spacecraft proximity operations... Nonlinear System (RNS). This assumption does not restrict the scope of these results in the context of SSA, as in orbital scenarios control and

  7. Applying WebMining on KM system

    NASA Astrophysics Data System (ADS)

    Shimazu, Keiko; Ozaki, Tomonobu; Furukawa, Koichi

    KM (Knowledge Management) systems have recently been adopted within the realm of enterprise management. On the other hand, data mining technology is widely acknowledged within Information systems' R&D Divisions. Specially, acquisition of meaningful information from Web usage data has become one of the most exciting eras. In this paper, we employ a Web based KM system and propose a framework for applying Web Usage Mining technology to KM data. As it turns out, task duration varies according to different user operations such as referencing a table-of-contents page, down-loading a target file, and writing to a bulletin board. This in turn makes it possible to easily predict the purpose of the user's task. By taking these observations into account, we segmented access log data manually. These results were compared with results abstained by applying the constant interval method. Next, we obtained a segmentation rule of Web access logs by applying a machine-learning algorithm to manually segmented access logs as training data. Then, the newly obtained segmentation rule was compared with other known methods including the time interval method by evaluating their segmentation results in terms of recall and precision rates and it was shown that our rule attained the best results in both measures. Furthermore, the segmented data were fed to an association rule miner and the obtained association rules were utilized to modify the Web structure.

  8. Positive Behavior Support and Applied Behavior Analysis

    PubMed Central

    Johnston, J.M; Foxx, Richard M; Jacobson, John W; Green, Gina; Mulick, James A

    2006-01-01

    This article reviews the origins and characteristics of the positive behavior support (PBS) movement and examines those features in the context of the field of applied behavior analysis (ABA). We raise a number of concerns about PBS as an approach to delivery of behavioral services and its impact on how ABA is viewed by those in human services. We also consider the features of PBS that have facilitated its broad dissemination and how ABA might benefit from emulating certain practices of the PBS movement. PMID:22478452

  9. Wavelet analysis applied to the IRAS cirrus

    NASA Technical Reports Server (NTRS)

    Langer, William D.; Wilson, Robert W.; Anderson, Charles H.

    1994-01-01

    The structure of infrared cirrus clouds is analyzed with Laplacian pyramid transforms, a form of non-orthogonal wavelets. Pyramid and wavelet transforms provide a means to decompose images into their spatial frequency components such that all spatial scales are treated in an equivalent manner. The multiscale transform analysis is applied to IRAS 100 micrometer maps of cirrus emission in the north Galactic pole region to extract features on different scales. In the maps we identify filaments, fragments and clumps by separating all connected regions. These structures are analyzed with respect to their Hausdorff dimension for evidence of the scaling relationships in the cirrus clouds.

  10. Applied Information Systems Research Program Workshop

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The first Applied Information Systems Research Program (AISRP) Workshop provided the impetus for several groups involved in information systems to review current activities. The objectives of the workshop included: (1) to provide an open forum for interaction and discussion of information systems; (2) to promote understanding by initiating a dialogue with the intended benefactors of the program, the scientific user community, and discuss options for improving their support; (3) create an advocacy in having science users and investigators of the program meet together and establish the basis for direction and growth; and (4) support the future of the program by building collaborations and interaction to encourage an investigator working group approach for conducting the program.

  11. Artificial intelligence applied to process signal analysis

    NASA Technical Reports Server (NTRS)

    Corsberg, Dan

    1988-01-01

    Many space station processes are highly complex systems subject to sudden, major transients. In any complex process control system, a critical aspect of the human/machine interface is the analysis and display of process information. Human operators can be overwhelmed by large clusters of alarms that inhibit their ability to diagnose and respond to a disturbance. Using artificial intelligence techniques and a knowledge base approach to this problem, the power of the computer can be used to filter and analyze plant sensor data. This will provide operators with a better description of the process state. Once a process state is recognized, automatic action could be initiated and proper system response monitored.

  12. The Applied Mathematics for Power Systems (AMPS)

    SciTech Connect

    Chertkov, Michael

    2012-07-24

    Increased deployment of new technologies, e.g., renewable generation and electric vehicles, is rapidly transforming electrical power networks by crossing previously distinct spatiotemporal scales and invalidating many traditional approaches for designing, analyzing, and operating power grids. This trend is expected to accelerate over the coming years, bringing the disruptive challenge of complexity, but also opportunities to deliver unprecedented efficiency and reliability. Our Applied Mathematics for Power Systems (AMPS) Center will discover, enable, and solve emerging mathematics challenges arising in power systems and, more generally, in complex engineered networks. We will develop foundational applied mathematics resulting in rigorous algorithms and simulation toolboxes for modern and future engineered networks. The AMPS Center deconstruction/reconstruction approach 'deconstructs' complex networks into sub-problems within non-separable spatiotemporal scales, a missing step in 20th century modeling of engineered networks. These sub-problems are addressed within the appropriate AMPS foundational pillar - complex systems, control theory, and optimization theory - and merged or 'reconstructed' at their boundaries into more general mathematical descriptions of complex engineered networks where important new questions are formulated and attacked. These two steps, iterated multiple times, will bridge the growing chasm between the legacy power grid and its future as a complex engineered network.

  13. A survey on fuzzy theory applied in geographic information system

    NASA Astrophysics Data System (ADS)

    Wu, Feiquan; Cui, Weihong; Chen, Houwu

    2009-10-01

    The real world is an infinite complex and very huge systems, the phenomenon and processes in this world have many complex relations among them. It is consecutive and cannot be treated as a determined one as the traditional geographic information system does; What's more, the uncertainty and fuzziness exist in every stage of data processing of GIS, from data collection, data storage to data analysis etc, so it is very meaningful to apply fuzzy theory in GIS for its ability to handle fuzziness and uncertainty of spatial data. The paper talks about the current situation of fuzzy theory applied in GIS, including the classification of application fields, its main methods, principles etc. The detailed fields we concerned include spatial object modeling, spatial reasoning, spatial analysis, spatial data mining, and reliability analysis of GIS data and so on. Furthermore, we put forward some development foregrounds and research orientations of fuzzy theory applied in GIS.

  14. A novel mating system analysis for modes of self-oriented mating applied to diploid and polyploid arctic Easter daisies (Townsendia hookeri).

    PubMed

    Thompson, S L; Ritland, K

    2006-08-01

    We have developed a new model for mating system analysis, which attempts to distinguish among alternative modes of self-oriented mating within populations. This model jointly estimates the rates of outcrossing, selfing, automixis and apomixis, through the use of information in the family structure given by dominant genetic marker data. The method is presented, its statistical properties evaluated, and is applied to three arctic Easter daisy populations, one consisting of diploids, the other two of tetraploids. The tetraploids are predominantly male sterile and reported to be apomictic while the diploids are male fertile. In each Easter daisy population, 10 maternal arrays of six progeny were assayed for amplified fragment length polymorphism markers. Estimates, confirmed with likelihood ratio tests of mating hypotheses, showed apomixis to be predominant in all populations (ca. 70%), but selfing or automixis was moderate (ca. 25%) in tetraploids. It was difficult to distinguish selfing from automixis, and simulations confirm that with even very large sample sizes, the estimates have a very strong negative statistical correlation, for example, they are not independent. No selfing or automixis was apparent in the diploid population, instead, moderate levels of outcrossing were detected (23%). Low but significant levels of outcrossing (2-4%) seemed to occur in the male-sterile tetraploid populations; this may be due to genotyping error of this level. Overall, this study shows apomixis can be partial, and provides evidence for higher levels of inbreeding in polyploids compared to diploids and for significant levels of apomixis in a diploid plant population.

  15. Applied spectrophotometry: analysis of a biochemical mixture.

    PubMed

    Trumbo, Toni A; Schultz, Emeric; Borland, Michael G; Pugh, Michael Eugene

    2013-01-01

    Spectrophotometric analysis is essential for determining biomolecule concentration of a solution and is employed ubiquitously in biochemistry and molecular biology. The application of the Beer-Lambert-Bouguer Lawis routinely used to determine the concentration of DNA, RNA or protein. There is however a significant difference in determining the concentration of a given species (RNA, DNA, protein) in isolation (a contrived circumstance) as opposed to determining that concentration in the presence of other species (a more realistic situation). To present the student with a more realistic laboratory experience and also to fill a hole that we believe exists in student experience prior to reaching a biochemistry course, we have devised a three week laboratory experience designed so that students learn to: connect laboratory practice with theory, apply the Beer-Lambert-Bougert Law to biochemical analyses, demonstrate the utility and limitations of example quantitative colorimetric assays, demonstrate the utility and limitations of UV analyses for biomolecules, develop strategies for analysis of a solution of unknown biomolecular composition, use digital micropipettors to make accurate and precise measurements, and apply graphing software.

  16. High Efficiency Micromachining System Applied in Nanolithography

    NASA Astrophysics Data System (ADS)

    Chen, Xing; Lee, Dong Weon; Choi, Young Soo

    Scanning probe lithography such as direct-writing lithographic processes and nanoscratching techniques based on scanning probe microscopy have presented new micromachining methods for microelectromechanical system (MEMS). In this paper, a micromachining system for thermal scanning probe lithography is introduced, which consists of the cantilever arrays and a big stroke micro XY-stage. A large machining area and high machining speed can be realized by combining arrays of cantilevers possessing sharp tips at their top with the novel micro XY-stage which can obtain big displacements under relatively low driving voltage and in a small size. According to the above configuration, this micromachining system is provided with high throughputs and suitable for industrialization due to its MEMS-based simple fabrication process. The novel micro XY-stage applied in this system is presented in detail including the unique structure and principles, which shows an obvious improvement and distinct advantages in comparison with traditional structures. It is analyzed by mathematical model and then simulated using finite element method (FEM), it is proved to be able to practically serve the micromachining system with high capability.

  17. Tribological systems as applied to aircraft engines

    NASA Technical Reports Server (NTRS)

    Buckley, D. H.

    1985-01-01

    Tribological systems as applied to aircraft are reviewed. The importance of understanding the fundamental concepts involved in such systems is discussed. Basic properties of materials which can be related to adhesion, friction and wear are presented and correlated with tribology. Surface processes including deposition and treatment are addressed in relation to their present and future application to aircraft components such as bearings, gears and seals. Lubrication of components with both liquids and solids is discussed. Advances in both new liquid molecular structures and additives for those structures are reviewed and related to the needs of advanced engines. Solids and polymer composites are suggested for increasing use and ceramic coatings containing fluoride compounds are offered for the extreme temperatures encountered in such components as advanced bearings and seals.

  18. Applied surface analysis in magnetic storage technology

    NASA Astrophysics Data System (ADS)

    Windeln, Johannes; Bram, Christian; Eckes, Heinz-Ludwig; Hammel, Dirk; Huth, Johanna; Marien, Jan; Röhl, Holger; Schug, Christoph; Wahl, Michael; Wienss, Andreas

    2001-07-01

    This paper gives a synopsis of today's challenges and requirements for a surface analysis and materials science laboratory with a special focus on magnetic recording technology. The critical magnetic recording components, i.e. the protective carbon overcoat (COC), the disk layer structure, the read/write head including the giant-magnetoresistive (GMR) sensor, are described and options for their characterization with specific surface and structure analysis techniques are given. For COC investigations, applications of Raman spectroscopy to the structural analysis and determination of thickness, hydrogen and nitrogen content are discussed. Hardness measurements by atomic force microscopy (AFM) scratching techniques are presented. Surface adsorption phenomena on disk substrates or finished disks are characterized by contact angle analysis or so-called piezo-electric mass adsorption systems (PEMAS), also known as quartz crystal microbalance (QCM). A quickly growing field of applications is listed for various X-ray analysis techniques, such as disk magnetic layer texture analysis for X-ray diffraction, compositional characterization via X-ray fluorescence, compositional analysis with high lateral resolution via electron microprobe analysis. X-ray reflectometry (XRR) has become a standard method for the absolute measurement of individual layer thicknesses contained in multi-layer stacks and thus, is the successor of ellipsometry for this application. Due to the ongoing reduction of critical feature sizes, the analytical challenges in terms of lateral resolution, sensitivity limits and dedicated nano-preparation have been consistently growing and can only be met by state-of-the-art Auger electron spectrometers (AES), transmission electron microscopy (TEM) analysis, time-of-flight-secondary ion mass spectroscopy (ToF-SIMS) characterization, focused ion beam (FIB) sectioning and TEM lamella preparation via FIB. The depth profiling of GMR sensor full stacks was significantly

  19. Tissue Microarray Analysis Applied to Bone Diagenesis

    PubMed Central

    Mello, Rafael Barrios; Silva, Maria Regina Regis; Alves, Maria Teresa Seixas; Evison, Martin Paul; Guimarães, Marco Aurelio; Francisco, Rafaella Arrabaca; Astolphi, Rafael Dias; Iwamura, Edna Sadayo Miazato

    2017-01-01

    Taphonomic processes affecting bone post mortem are important in forensic, archaeological and palaeontological investigations. In this study, the application of tissue microarray (TMA) analysis to a sample of femoral bone specimens from 20 exhumed individuals of known period of burial and age at death is described. TMA allows multiplexing of subsamples, permitting standardized comparative analysis of adjacent sections in 3-D and of representative cross-sections of a large number of specimens. Standard hematoxylin and eosin, periodic acid-Schiff and silver methenamine, and picrosirius red staining, and CD31 and CD34 immunohistochemistry were applied to TMA sections. Osteocyte and osteocyte lacuna counts, percent bone matrix loss, and fungal spheroid element counts could be measured and collagen fibre bundles observed in all specimens. Decalcification with 7% nitric acid proceeded more rapidly than with 0.5 M EDTA and may offer better preservation of histological and cellular structure. No endothelial cells could be detected using CD31 and CD34 immunohistochemistry. Correlation between osteocytes per lacuna and age at death may reflect reported age-related responses to microdamage. Methodological limitations and caveats, and results of the TMA analysis of post mortem diagenesis in bone are discussed, and implications for DNA survival and recovery considered. PMID:28051148

  20. Overview of MSFC's Applied Fluid Dynamics Analysis Group Activities

    NASA Technical Reports Server (NTRS)

    Garcia, Roberto; Griffin, Lisa; Williams, Robert

    2002-01-01

    This viewgraph report presents an overview of activities and accomplishments of NASA's Marshall Space Flight Center's Applied Fluid Dynamics Analysis Group. Expertise in this group focuses on high-fidelity fluids design and analysis with application to space shuttle propulsion and next generation launch technologies. Topics covered include: computational fluid dynamics research and goals, turbomachinery research and activities, nozzle research and activities, combustion devices, engine systems, MDA development and CFD process improvements.

  1. Computing and Systems Applied in Support of Coordinated ...

    EPA Pesticide Factsheets

    This talk focuses on how Dr. Loughlin is applying Computing and Systems models, tools and methods to more fully understand the linkages among energy systems, environmental quality, and climate change. Dr. Loughlin will highlight recent and ongoing research activities, including: applying sensitivity analysis to assess the impacts of clean energy technologies, conducting scenario analysis to explore the efficacy of environmental regulations under deep uncertainty, and developing decision support systems that allow analysts and decision-makers to examine state-level climate actions. Dr. Loughlin will conclude with a brief discussion of the lessons learned over the first half of his career. Dr. Loughlin has been invited to give the keynote talk at the 1st Annual Computing and Systems Graduate Research Symposium, sponsored by the Department of Civil, Construction and Environmental Engineering at North Carolina State University.

  2. Use of an automated chromium reduction system for hydrogen isotope ratio analysis of physiological fluids applied to doubly labeled water analysis.

    PubMed

    Schoeller, D A; Colligan, A S; Shriver, T; Avak, H; Bartok-Olson, C

    2000-09-01

    The doubly labeled water method is commonly used to measure total energy expenditure in free-living subjects. The method, however, requires accurate and precise deuterium abundance determinations, which can be laborious. The aim of this study was to evaluate a fully automated, high-throughput, chromium reduction technique for the measurement of deuterium abundances in physiological fluids. The chromium technique was compared with an off-line zinc bomb reduction technique and also subjected to test-retest analysis. Analysis of international water standards demonstrated that the chromium technique was accurate and had a within-day precision of <1 per thousand. Addition of organic matter to water samples demonstrated that the technique was sensitive to interference at levels between 2 and 5 g l(-1). Physiological samples could be analyzed without this interference, plasma by 10000 Da exclusion filtration, saliva by sedimentation and urine by decolorizing with carbon black. Chromium reduction of urine specimens from doubly labeled water studies indicated no bias relative to zinc reduction with a mean difference in calculated energy expenditure of -0.2 +/- 3.9%. Blinded reanalysis of urine specimens from a second doubly labeled water study demonstrated a test-retest coefficient of variation of 4%. The chromium reduction method was found to be a rapid, accurate and precise method for the analysis of urine specimens from doubly labeled water.

  3. [Systemic reactions to orally applied metal alloys].

    PubMed

    Feilzer, A J; Kleverlaan, C J; Prahl, C; Muris, J

    2013-06-01

    Orally applied metal alloys can cause undesirable physical effects. A distinction needs to be made in this respect between local and systemic reactions and toxic and immunological reactions. A case is presented which illustrates this problem. In this case, the application of orthodontic appliances was probably the trigger for an exacerbation of nickel allergy. The oral exposure to nickel resulted in hand eczema. The patient was also exposed to nickel by single-unit fixed dental prostheses, a removable dental prosthesis, and food, as a result of which removal of the orthodontic appliances did not result in complete healing. Therefore, the single-unit fixed dental prostheses also had to be removed and food had to be prepared henceforward in nickel free pans.

  4. Cluster analysis applied to multiparameter geophysical dataset

    NASA Astrophysics Data System (ADS)

    Di Giuseppe, M. G.; Troiano, A.; Troise, C.; De Natale, G.

    2012-04-01

    Multi-parameter acquisition is a common geophysical field practice nowadays. Regularly seismic velocity and attenuation, gravity and electromagnetic dataset are acquired in a certain area, to obtain a complete characterization of the some investigate feature of the subsoil. Such a richness of information is often underestimated, although an integration of the analysis could provide a notable improving in the imaging of the investigated structures, mostly because the handling of distinct parameters and their joint inversion still presents several and severe problems. Post-inversion statistical techniques represent a promising approach to these questions, providing a quick, simple and elegant way to obtain this advantageous but complex integration. We present an approach based on the partition of the analyzed multi parameter dataset in a number of different classes, identified as localized regions of high correlation. These classes, or 'Cluster', are structured in such a way that the observations pertaining to a certain group are more similar to each other than the observations belonging to a different one, according to an optimal logical criterion. Regions of the subsoil sharing the same physical characteristic are so identified, without a-priori or empirical relationship linking the distinct measured parameters. The retrieved imaging results highly affordable in a statistical sense, specifically due to this lack of external hypothesis that are, instead, indispensable in a full joint inversion, were works, as matter of fact, just a real constrain for the inversion process, not seldom of relative consistence. We apply our procedure to a certain number of experimental dataset, related to several structures at very different scales presents in the Campanian district (southern Italy). These structures goes from the shallows evidence of the active fault zone originating the M 7.9 Irpinia earthquake to the main feature characterizing the Campi Flegrei Caldera and the Mt

  5. System safety as applied to Skylab

    NASA Technical Reports Server (NTRS)

    Kleinknecht, K. S.; Miller, B. J.

    1974-01-01

    Procedural and organizational guidelines used in accordance with NASA safety policy for the Skylab missions are outlined. The basic areas examined in the safety program for Skylab were the crew interface, extra-vehicular activity (EVA), energy sources, spacecraft interface, and hardware complexity. Fire prevention was a primary goal, with firefighting as backup. Studies of the vectorcardiogram and sleep monitoring experiments exemplify special efforts to prevent fire and shock. The final fire control study included material review, fire detection capability, and fire extinguishing capability. Contractors had major responsibility for system safety. Failure mode and effects analysis (FMEA) and equipment criticality categories are outlined. Redundancy was provided on systems that were critical to crew survival (category I). The five key checkpoints in Skylab hardware development are explained. Skylab rescue capability was demonstrated by preparations to rescue the Skylab 3 crew after their spacecraft developed attitude control problems.

  6. Magnetic Analysis Techniques Applied to Desert Varnish

    NASA Technical Reports Server (NTRS)

    Schmidgall, E. R.; Moskowitz, B. M.; Dahlberg, E. D.; Kuhlman, K. R.

    2003-01-01

    Desert varnish is a black or reddish coating commonly found on rock samples from arid regions. Typically, the coating is very thin, less than half a millimeter thick. Previous research has shown that the primary components of desert varnish are silicon oxide clay minerals (60%), manganese and iron oxides (20-30%), and trace amounts of other compounds [1]. Desert varnish is thought to originate when windborne particles containing iron and manganese oxides are deposited onto rock surfaces where manganese oxidizing bacteria concentrate the manganese and form the varnish [4,5]. If desert varnish is indeed biogenic, then the presence of desert varnish on rock surfaces could serve as a biomarker, indicating the presence of microorganisms. This idea has considerable appeal, especially for Martian exploration [6]. Magnetic analysis techniques have not been extensively applied to desert varnish. The only previous magnetic study reported that based on room temperature demagnetization experiments, there were noticeable differences in magnetic properties between a sample of desert varnish and the substrate sandstone [7]. Based upon the results of the demagnetization experiments, the authors concluded that the primary magnetic component of desert varnish was either magnetite (Fe3O4) or maghemite ( Fe2O3).

  7. Analysis of the interaction between experimental and applied behavior analysis.

    PubMed

    Virues-Ortega, Javier; Hurtado-Parrado, Camilo; Cox, Alison D; Pear, Joseph J

    2014-01-01

    To study the influences between basic and applied research in behavior analysis, we analyzed the coauthorship interactions of authors who published in JABA and JEAB from 1980 to 2010. We paid particular attention to authors who published in both JABA and JEAB (dual authors) as potential agents of cross-field interactions. We present a comprehensive analysis of dual authors' coauthorship interactions using social networks methodology and key word analysis. The number of dual authors more than doubled (26 to 67) and their productivity tripled (7% to 26% of JABA and JEAB articles) between 1980 and 2010. Dual authors stood out in terms of number of collaborators, number of publications, and ability to interact with multiple groups within the field. The steady increase in JEAB and JABA interactions through coauthors and the increasing range of topics covered by dual authors provide a basis for optimism regarding the progressive integration of basic and applied behavior analysis.

  8. Research in applied mathematics, numerical analysis, and computer science

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Research conducted at the Institute for Computer Applications in Science and Engineering (ICASE) in applied mathematics, numerical analysis, and computer science is summarized and abstracts of published reports are presented. The major categories of the ICASE research program are: (1) numerical methods, with particular emphasis on the development and analysis of basic numerical algorithms; (2) control and parameter identification; (3) computational problems in engineering and the physical sciences, particularly fluid dynamics, acoustics, and structural analysis; and (4) computer systems and software, especially vector and parallel computers.

  9. Toward applied behavior analysis of life aloft.

    PubMed

    Brady, J V

    1990-01-01

    This article deals with systems at multiple levels, at least from cell to organization. It also deals with learning, decision making, and other behavior at multiple levels. Technological development of a human behavioral ecosystem appropriate to space environments requires an analytic and synthetic orientation, explicitly experimental in nature, dictated by scientific and pragmatic considerations, and closely approximating procedures of established effectiveness in other areas of natural science. The conceptual basis of such an approach has its roots in environmentalism which has two main features: (1) knowledge comes from experience rather than from innate ideas, divine revelation, or other obscure sources; and (2) action is governed by consequences rather than by instinct, reason, will, beliefs, attitudes or even the currently fashionable cognitions. Without an experimentally derived data base founded upon such a functional analysis of human behavior, the overgenerality of "ecological systems" approaches render them incapable of ensuring the successful establishment of enduring space habitats. Without an experimentally derived function account of individual behavioral variability, a natural science of behavior cannot exist. And without a natural science of behavior, the social sciences will necessarily remain in their current status as disciplines of less than optimal precision or utility. Such a functional analysis of human performance should provide an operational account of behavior change in a manner similar to the way in which Darwin's approach to natural selection accounted for the evolution of phylogenetic lines (i.e., in descriptive, nonteleological terms). Similarly, as Darwin's account has subsequently been shown to be consonant with information obtained at the cellular level, so too should behavior principles ultimately prove to be in accord with an account of ontogenetic adaptation at a biochemical level. It would thus seem obvious that the most

  10. Toward applied behavior analysis of life aloft

    NASA Technical Reports Server (NTRS)

    Brady, J. V.

    1990-01-01

    This article deals with systems at multiple levels, at least from cell to organization. It also deals with learning, decision making, and other behavior at multiple levels. Technological development of a human behavioral ecosystem appropriate to space environments requires an analytic and synthetic orientation, explicitly experimental in nature, dictated by scientific and pragmatic considerations, and closely approximating procedures of established effectiveness in other areas of natural science. The conceptual basis of such an approach has its roots in environmentalism which has two main features: (1) knowledge comes from experience rather than from innate ideas, divine revelation, or other obscure sources; and (2) action is governed by consequences rather than by instinct, reason, will, beliefs, attitudes or even the currently fashionable cognitions. Without an experimentally derived data base founded upon such a functional analysis of human behavior, the overgenerality of "ecological systems" approaches render them incapable of ensuring the successful establishment of enduring space habitats. Without an experimentally derived function account of individual behavioral variability, a natural science of behavior cannot exist. And without a natural science of behavior, the social sciences will necessarily remain in their current status as disciplines of less than optimal precision or utility. Such a functional analysis of human performance should provide an operational account of behavior change in a manner similar to the way in which Darwin's approach to natural selection accounted for the evolution of phylogenetic lines (i.e., in descriptive, nonteleological terms). Similarly, as Darwin's account has subsequently been shown to be consonant with information obtained at the cellular level, so too should behavior principles ultimately prove to be in accord with an account of ontogenetic adaptation at a biochemical level. It would thus seem obvious that the most

  11. Subpixels analysis model applied to floodplain monitoring

    NASA Astrophysics Data System (ADS)

    Giraldo Osorio, J. D.; García Galiano, S. G.

    2009-04-01

    The traditional techniques to gauge hydrological events often fail with the extreme events. A particular case is the floods spatial detection. In this work, the remote sensing techniques and Geographic Information Systems (GIS) have been merged to develop a key tool for monitoring of floods. The low density of gauge stations networks in the development countries becomes remote sensing techniques the most suitable and economic way to delimitate the flood area and compute the damages cost. The common classification techniques of satellite images use "hard methods" in the sense of a pixel is assigned to an unique land cover class. For coarse resolution, the pixels inevitably will be mixed, so "soft methods" can be used in order to assign several land cover classes according to the surface fractions covered by each one. The main objective of this work is the dynamic monitoring of floods in large areas, based on satellite images -with moderate spatial resolution but with high time resolution- and Digital Elevation Model (DEM). Classified maps with finer spatial resolution can be built through the methodology of Subpixels Analysis developed. The procedure is supported on both the Linear Mixture Model (LMM) and Spatial Coherence Analysis (SCA) hypothesis. The LMM builds the land cover fraction maps through an optimization procedure which uses Lagrange Multipliers, while the SCA defines the most likely place for the land cover fractions within the coarse pixel using linear programming. A subsequent procedure improves the flooded area identification using both the drainage direction and flow accumulation raster maps derived from DEM of the study zone. The Subpixels Analysis technique was validated using historical data of floods which were obtained from satellite images. The procedure improves the spatial resolution of classified maps from satellite images with coarse resolution, while the "hard methods" keep the spatial resolution from the input coarse satellite image.

  12. Image analysis applied to luminescence microscopy

    NASA Astrophysics Data System (ADS)

    Maire, Eric; Lelievre-Berna, Eddy; Fafeur, Veronique; Vandenbunder, Bernard

    1998-04-01

    We have developed a novel approach to study luminescent light emission during migration of living cells by low-light imaging techniques. The equipment consists in an anti-vibration table with a hole for a direct output under the frame of an inverted microscope. The image is directly captured by an ultra low- light level photon-counting camera equipped with an image intensifier coupled by an optical fiber to a CCD sensor. This installation is dedicated to measure in a dynamic manner the effect of SF/HGF (Scatter Factor/Hepatocyte Growth Factor) both on activation of gene promoter elements and on cell motility. Epithelial cells were stably transfected with promoter elements containing Ets transcription factor-binding sites driving a luciferase reporter gene. Luminescent light emitted by individual cells was measured by image analysis. Images of luminescent spots were acquired with a high aperture objective and time exposure of 10 - 30 min in photon-counting mode. The sensitivity of the camera was adjusted to a high value which required the use of a segmentation algorithm dedicated to eliminate the background noise. Hence, image segmentation and treatments by mathematical morphology were particularly indicated in these experimental conditions. In order to estimate the orientation of cells during their migration, we used a dedicated skeleton algorithm applied to the oblong spots of variable intensities emitted by the cells. Kinetic changes of luminescent sources, distance and speed of migration were recorded and then correlated with cellular morphological changes for each spot. Our results highlight the usefulness of the mathematical morphology to quantify kinetic changes in luminescence microscopy.

  13. Digital photoelastic analysis applied to implant dentistry

    NASA Astrophysics Data System (ADS)

    Ramesh, K.; Hariprasad, M. P.; Bhuvanewari, S.

    2016-12-01

    Development of improved designs of implant systems in dentistry have necessitated the study of stress fields in the implant regions of the mandible/maxilla for better understanding of the biomechanics involved. Photoelasticity has been used for various studies related to dental implants in view of whole field visualization of maximum shear stress in the form of isochromatic contours. The potential of digital photoelasticity has not been fully exploited in the field of implant dentistry. In this paper, the fringe field in the vicinity of the connected implants (All-On-Four® concept) is analyzed using recent advances in digital photoelasticity. Initially, a novel 3-D photoelastic model making procedure, to closely mimic all the anatomical features of the human mandible is proposed. By choosing appropriate orientation of the model with respect to the light path, the essential region of interest were sought to be analysed while keeping the model under live loading conditions. Need for a sophisticated software module to carefully identify the model domain has been brought out. For data extraction, five-step method is used and isochromatics are evaluated by twelve fringe photoelasticity. In addition to the isochromatic fringe field, whole field isoclinic data is also obtained for the first time in implant dentistry, which could throw important information in improving the structural stability of the implant systems. Analysis is carried out for the implant in the molar as well as the incisor region. In addition, the interaction effects of loaded molar implant on the incisor area are also studied.

  14. Moving Forward: Positive Behavior Support and Applied Behavior Analysis

    ERIC Educational Resources Information Center

    Tincani, Matt

    2007-01-01

    A controversy has emerged about the relationship between positive behavior support and applied behavior analysis. Some behavior analysts suggest that positive behavior support and applied behavior analysis are the same (e.g., Carr & Sidener, 2002). Others argue that positive behavior support is harmful to applied behavior analysis (e.g., Johnston,…

  15. Classical mechanics approach applied to analysis of genetic oscillators.

    PubMed

    Vasylchenkova, Anastasiia; Mraz, Miha; Zimic, Nikolaj; Moskon, Miha

    2016-04-05

    Biological oscillators present a fundamental part of several regulatory mechanisms that control the response of various biological systems. Several analytical approaches for their analysis have been reported recently. They are, however, limited to only specific oscillator topologies and/or to giving only qualitative answers, i.e., is the dynamics of an oscillator given the parameter space oscillatory or not. Here we present a general analytical approach that can be applied to the analysis of biological oscillators. It relies on the projection of biological systems to classical mechanics systems. The approach is able to provide us with relatively accurate results in the meaning of type of behaviour system reflects (i.e. oscillatory or not) and periods of potential oscillations without the necessity to conduct expensive numerical simulations. We demonstrate and verify the proposed approach on three different implementations of amplified negative feedback oscillator.

  16. Fluorescent protein biosensors applied to microphysiological systems

    PubMed Central

    Senutovitch, Nina; Boltz, Robert; DeBiasio, Richard; Gough, Albert; Taylor, D Lansing

    2015-01-01

    This mini-review discusses the evolution of fluorescence as a tool to study living cells and tissues in vitro and the present role of fluorescent protein biosensors (FPBs) in microphysiological systems (MPSs). FPBs allow the measurement of temporal and spatial dynamics of targeted cellular events involved in normal and perturbed cellular assay systems and MPSs in real time. FPBs evolved from fluorescent analog cytochemistry (FAC) that permitted the measurement of the dynamics of purified proteins covalently labeled with environmentally insensitive fluorescent dyes and then incorporated into living cells, as well as a large list of diffusible fluorescent probes engineered to measure environmental changes in living cells. In parallel, a wide range of fluorescence microscopy methods were developed to measure the chemical and molecular activities of the labeled cells, including ratio imaging, fluorescence lifetime, total internal reflection, 3D imaging, including super-resolution, as well as high-content screening. FPBs evolved from FAC by combining environmentally sensitive fluorescent dyes with proteins in order to monitor specific physiological events such as post-translational modifications, production of metabolites, changes in various ion concentrations, and the dynamic interaction of proteins with defined macromolecules in time and space within cells. Original FPBs involved the engineering of fluorescent dyes to sense specific activities when covalently attached to particular domains of the targeted protein. The subsequent development of fluorescent proteins (FPs), such as the green fluorescent protein, dramatically accelerated the adoption of studying living cells, since the genetic “labeling” of proteins became a relatively simple method that permitted the analysis of temporal–spatial dynamics of a wide range of proteins. Investigators subsequently engineered the fluorescence properties of the FPs for environmental sensitivity that, when combined with

  17. Liquid Chromatography Applied to Space System

    NASA Astrophysics Data System (ADS)

    Poinot, Pauline; Chazalnoel, Pascale; Geffroy, Claude; Sternberg, Robert; Carbonnier, Benjamin

    Searching for signs of past or present life in our Solar System is a real challenge that stirs up the curiosity of scientists. Until now, in situ instrumentation was designed to detect and determine concentrations of a wide number of organic biomarkers. The relevant method which was and still is employed in missions dedicated to the quest of life (from Viking to ExoMars) corresponds to the pyrolysis-GC-MS. Along the missions, this approach has been significantly improved in terms of extraction efficiency and detection with the use of chemical derivative agents (e.g. MTBSTFA, DMF-DMA, TMAH…), and in terms of analysis sensitivity and resolution with the development of in situ high-resolution mass spectrometer (e.g. TOF-MS). Thanks to such an approach, organic compounds such as amino acids, sugars, tholins or polycyclic aromatic hydrocarbons (PAHs) were expected to be found. However, while there’s a consensus that the GC-MS of Viking, Huygens, MSL and MOMA space missions worked the way they had been designed to, pyrolysis is much more in debate (Glavin et al. 2001; Navarro-González et al. 2006). Indeed, (1) it is thought to remove low levels of organics, (2) water and CO2 could interfere with the detection of likely organic pyrolysis products, and (3) only low to mid-molecular weight organic molecules can be detected by this technique. As a result, researchers are now focusing on other in situ techniques which are no longer based on the volatility of the organic matter, but on the liquid phase extraction and analysis. In this line, micro-fluidic systems involving sandwich and/or competitive immunoassays (e.g. LMC, SOLID; Parro et al. 2005; Sims et al. 2012), micro-chip capillary electrophoreses (e.g. MOA; Bada et al. 2008), or nanopore-based analysis (e.g. BOLD; Schulze-Makuch et al. 2012) have been conceived for in situ analysis. Thanks to such approaches, molecular biological polymers (polysaccharides, polypeptides, polynucleotides, phospholipids, glycolipids

  18. Applying Mechanics to Swimming Performance Analysis.

    ERIC Educational Resources Information Center

    Barthels, Katharine

    1989-01-01

    Swimming teachers and coaches can improve their feedback to swimmers, when correcting or refining swim movements, by applying some basic biomechanical concepts relevant to swimming. This article focuses on the biomechanical considerations used in analyzing swimming performance. Techniques for spotting and correcting problems that impede…

  19. Introduction: Conversation Analysis in Applied Linguistics

    ERIC Educational Resources Information Center

    Sert, Olcay; Seedhouse, Paul

    2011-01-01

    This short, introductory paper presents an up-to-date account of works within the field of Applied Linguistics which have been influenced by a Conversation Analytic paradigm. The article reviews recent studies in classroom interaction, materials development, proficiency assessment and language teacher education. We believe that the publication of…

  20. Sensitivity and specificity analysis of fringing-field dielectric spectroscopy applied to a multi-layer system modelling the human skin.

    PubMed

    Huclova, Sonja; Baumann, Dirk; Talary, Mark S; Fröhlich, Jürg

    2011-12-21

    The sensitivity and specificity of dielectric spectroscopy for the detection of dielectric changes inside a multi-layered structure is investigated. We focus on providing a base for sensing physiological changes in the human skin, i.e. in the epidermal and dermal layers. The correlation between changes of the human skin's effective permittivity and changes of dielectric parameters and layer thickness of the epidermal and dermal layers is assessed using numerical simulations. Numerical models include fringing-field probes placed directly on a multi-layer model of the skin. The resulting dielectric spectra in the range from 100 kHz up to 100 MHz for different layer parameters and sensor geometries are used for a sensitivity and specificity analysis of this multi-layer system. First, employing a coaxial probe, a sensitivity analysis is performed for specific variations of the parameters of the epidermal and dermal layers. Second, the specificity of this system is analysed based on the roots and corresponding sign changes of the computed dielectric spectra and their first and second derivatives. The transferability of the derived results is shown by a comparison of the dielectric spectra of a coplanar probe and a scaled coaxial probe. Additionally, a comparison of the sensitivity of a coaxial probe and an interdigitated probe as a function of electrode distance is performed. It is found that the sensitivity for detecting changes of dielectric properties in the epidermal and dermal layers strongly depends on frequency. Based on an analysis of the dielectric spectra, changes in the effective dielectric parameters can theoretically be uniquely assigned to specific changes in permittivity and conductivity. However, in practice, measurement uncertainties may degrade the performance of the system.

  1. Sensitivity and specificity analysis of fringing-field dielectric spectroscopy applied to a multi-layer system modelling the human skin

    NASA Astrophysics Data System (ADS)

    Huclova, Sonja; Baumann, Dirk; Talary, Mark S.; Fröhlich, Jürg

    2011-12-01

    The sensitivity and specificity of dielectric spectroscopy for the detection of dielectric changes inside a multi-layered structure is investigated. We focus on providing a base for sensing physiological changes in the human skin, i.e. in the epidermal and dermal layers. The correlation between changes of the human skin's effective permittivity and changes of dielectric parameters and layer thickness of the epidermal and dermal layers is assessed using numerical simulations. Numerical models include fringing-field probes placed directly on a multi-layer model of the skin. The resulting dielectric spectra in the range from 100 kHz up to 100 MHz for different layer parameters and sensor geometries are used for a sensitivity and specificity analysis of this multi-layer system. First, employing a coaxial probe, a sensitivity analysis is performed for specific variations of the parameters of the epidermal and dermal layers. Second, the specificity of this system is analysed based on the roots and corresponding sign changes of the computed dielectric spectra and their first and second derivatives. The transferability of the derived results is shown by a comparison of the dielectric spectra of a coplanar probe and a scaled coaxial probe. Additionally, a comparison of the sensitivity of a coaxial probe and an interdigitated probe as a function of electrode distance is performed. It is found that the sensitivity for detecting changes of dielectric properties in the epidermal and dermal layers strongly depends on frequency. Based on an analysis of the dielectric spectra, changes in the effective dielectric parameters can theoretically be uniquely assigned to specific changes in permittivity and conductivity. However, in practice, measurement uncertainties may degrade the performance of the system.

  2. Expert systems applied to spacecraft fire safety

    NASA Technical Reports Server (NTRS)

    Smith, Richard L.; Kashiwagi, Takashi

    1989-01-01

    Expert systems are problem-solving programs that combine a knowledge base and a reasoning mechanism to simulate a human expert. The development of an expert system to manage fire safety in spacecraft, in particular the NASA Space Station Freedom, is difficult but clearly advantageous in the long-term. Some needs in low-gravity flammability characteristics, ventilating-flow effects, fire detection, fire extinguishment, and decision models, all necessary to establish the knowledge base for an expert system, are discussed.

  3. pH recycling aqueous two-phase systems applied in extraction of Maitake β-Glucan and mechanism analysis using low-field nuclear magnetic resonance.

    PubMed

    Hou, Huiyun; Cao, Xuejun

    2015-07-31

    In this paper, a recycling aqueous two-phase systems (ATPS) based on two pH-response copolymers PADB and PMDM were used in purification of β-Glucan from Grifola frondosa. The main parameters, such as polymer concentration, type and concentration of salt, extraction temperature and pH, were investigated to optimize partition conditions. The results demonstrated that β-Glucan was extracted into PADB-rich phase, while impurities were extracted into PMDM-rich phase. In this 2.5% PADB/2.5% PMDM ATPS, 7.489 partition coefficient and 96.92% extraction recovery for β-Glucan were obtained in the presence of 30mmol/L KBr, at pH 8.20, 30°C. The phase-forming copolymers could be recycled by adjusting pH, with recoveries of over 96.0%. Furthermore, the partition mechanism of Maitake β-Glucan in PADB/PMDM aqueous two-phase systems was studied. Fourier transform infrared spectra, ForteBio Octet system and low-field nuclear magnetic resonance (LF-NMR) were introduced for elucidating the partition mechanism of β-Glucan. Especially, LF-NMR was firstly used in the mechanism analysis in partition of aqueous two-phase systems. The change of transverse relaxation time (T2) in ATPS could reflect the interaction between polymers and β-Glucan.

  4. Meta-analysis in applied ecology.

    PubMed

    Stewart, Gavin

    2010-02-23

    This overview examines research synthesis in applied ecology and conservation. Vote counting and pooling unweighted averages are widespread despite the superiority of syntheses based on weighted combination of effects. Such analyses allow exploration of methodological uncertainty in addition to consistency of effects across species, space and time, but exploring heterogeneity remains controversial. Meta-analyses are required to generalize in ecology, and to inform evidence-based decision-making, but the more sophisticated statistical techniques and registers of research used in other disciplines must be employed in ecology to fully realize their benefits.

  5. Applying Modeling Tools to Ground System Procedures

    NASA Technical Reports Server (NTRS)

    Di Pasquale, Peter

    2012-01-01

    As part of a long-term effort to revitalize the Ground Systems (GS) Engineering Section practices, Systems Modeling Language (SysML) and Business Process Model and Notation (BPMN) have been used to model existing GS products and the procedures GS engineers use to produce them.

  6. EG G Mound Applied Technologies payroll system

    SciTech Connect

    Not Available

    1992-02-07

    EG G Mound Applied Technologies, Inc., manages and operates the Mound Facility, Miamisburg, Ohio, under a cost-plus-award-fee contract administered by the Department of Energy's Albuquerque Field Office. The contractor's Payroll Department is responsible for prompt payment in the proper amount to all persons entitled to be paid, in compliance with applicable laws, regulations, and legal decisions. The objective was to determine whether controls were in place to avoid erroneous payroll payments. EG G Mound Applied Technologies, Inc., did not have all the internal controls required by General Accounting Office Title 6, Pay, Leave, and Allowances.'' Specifically, they did not have computerized edits, separation of duties and responsibilities, and restricted access to payroll data files. This condition occurred because its managers were not aware of Title 6 requirements. As a result, the contractor could not assure the Department of Energy that payroll costs were processes accurately; and fraud, waste, or abuse of Department of Energy funds could go undetected. Our sample of 212 payroll transactions from a population of 66,000 in FY 1991 disclosed only two minor processing errors and no instances of fraud, waste or abuse.

  7. Does terrestrial epidemiology apply to marine systems?

    USGS Publications Warehouse

    McCallum, Hamish I.; Kuris, Armand M.; Harvell, C. Drew; Lafferty, Kevin D.; Smith, Garriet W.; Porter, James

    2004-01-01

    Most of epidemiological theory has been developed for terrestrial systems, but the significance of disease in the ocean is now being recognized. However, the extent to which terrestrial epidemiology can be directly transferred to marine systems is uncertain. Many broad types of disease-causing organism occur both on land and in the sea, and it is clear that some emergent disease problems in marine environments are caused by pathogens moving from terrestrial to marine systems. However, marine systems are qualitatively different from terrestrial environments, and these differences affect the application of modelling and management approaches that have been developed for terrestrial systems. Phyla and body plans are more diverse in marine environments and marine organisms have different life histories and probably different disease transmission modes than many of their terrestrial counterparts. Marine populations are typically more open than terrestrial ones, with the potential for long-distance dispersal of larvae. Potentially, this might enable unusually rapid propagation of epidemics in marine systems, and there are several examples of this. Taken together, these differences will require the development of new approaches to modelling and control of infectious disease in the ocean.

  8. Applied Spectrophotometry: Analysis of a Biochemical Mixture

    ERIC Educational Resources Information Center

    Trumbo, Toni A.; Schultz, Emeric; Borland, Michael G.; Pugh, Michael Eugene

    2013-01-01

    Spectrophotometric analysis is essential for determining biomolecule concentration of a solution and is employed ubiquitously in biochemistry and molecular biology. The application of the Beer-Lambert-Bouguer Lawis routinely used to determine the concentration of DNA, RNA or protein. There is however a significant difference in determining the…

  9. Thermal analysis applied to irradiated propolis

    NASA Astrophysics Data System (ADS)

    Matsuda, Andrea Harumi; Machado, Luci Brocardo; del Mastro, Nélida Lucia

    2002-03-01

    Propolis is a resinous hive product, collected by bees. Raw propolis requires a decontamination procedure and irradiation appears as a promising technique for this purpose. The valuable properties of propolis for food and pharmaceutical industries have led to increasing interest in its technological behavior. Thermal analysis is a chemical analysis that gives information about changes on heating of great importance for technological applications. Ground propolis samples were 60Co gamma irradiated with 0 and 10 kGy. Thermogravimetry curves shown a similar multi-stage decomposition pattern for both irradiated and unirradiated samples up to 600°C. Similarly, through differential scanning calorimetry , a coincidence of melting point of irradiated and unirradiated samples was found. The results suggest that the irradiation process do not interfere on the thermal properties of propolis when irradiated up to 10 kGy.

  10. Biomechanics and motion analysis applied to sports.

    PubMed

    Zheng, N; Barrentine, S W

    2000-05-01

    The development of motion analysis and the application of biomechanical analysis techniques to sports has paralleled the exponential growth of computational and videographic technology. Technological developments have provided for advances in the investigation of the human body and the action of the human body during sports believed to be unobtainable a few years ago. Technological advancements have brought biomechanical applications into a wide range of fields from orthopedics to entertainment. An area that has made tremendous gains using biomechanics is sports science. Coaches, therapists, and physicians are using biomechanics to improve performance, rehabilitation, and the prevention of sports related injuries. Functional analyses of athletic movements that were impossible a few years ago are available and used today. With new advancements, the possibilities for investigating the way a human interacts and reacts to environmental conditions are ever expanding.

  11. Applying thiouracil tagging to mouse transcriptome analysis.

    PubMed

    Gay, Leslie; Karfilis, Kate V; Miller, Michael R; Doe, Chris Q; Stankunas, Kryn

    2014-02-01

    Transcriptional profiling is a powerful approach for studying mouse development, physiology and disease models. Here we describe a protocol for mouse thiouracil tagging (TU tagging), a transcriptome analysis technology that includes in vivo covalent labeling, purification and analysis of cell type-specific RNA. TU tagging enables the isolation of RNA from a given cell population of a complex tissue, avoiding transcriptional changes induced by cell isolation trauma, as well as the identification of actively transcribed RNAs and not preexisting transcripts. Therefore, in contrast to other cell-specific transcriptional profiling methods based on the purification of tagged ribosomes or nuclei, TU tagging provides a direct examination of transcriptional regulation. We describe how to (i) deliver 4-thiouracil to transgenic mice to thio-label cell lineage-specific transcripts, (ii) purify TU-tagged RNA and prepare libraries for Illumina sequencing and (iii) follow a straightforward bioinformatics workflow to identify cell type-enriched or differentially expressed genes. Tissue containing TU-tagged RNA can be obtained in 1 d, RNA-seq libraries can be generated within 2 d and, after sequencing, an initial bioinformatics analysis can be completed in 1 additional day.

  12. Sociotechnical Systems as Applied to Knowledge Work

    DTIC Science & Technology

    1998-06-01

    technology forums. The research will compare earlier studies of variations and forums to new studies involving intellectual capital , knowledge bases...knowledge development, intellectual capital and collaborative software. Chapter III details the development of the sociotechnical systems...development and intellectual capital to determine consistency among the variances and forums that contribute to barriers in the deliberation process. It

  13. Volatility Measurements Applied to Information Systems

    DTIC Science & Technology

    2013-09-01

    differences in metrics ( Sahin , 2006). Risk diversification is optimization across several systems and finally, risk management deals with the tracking and...from http://search.proquest.com/docview/232571921?accountid=12702 Sahin , I. (2006). Detailed review of Rogers’ diffusion of innovations theory and

  14. Systems biology: the reincarnation of systems theory applied in biology?

    PubMed

    Wolkenhauer, O

    2001-09-01

    With the availability of quantitative data on the transcriptome and proteome level, there is an increasing interest in formal mathematical models of gene expression and regulation. International conferences, research institutes and research groups concerned with systems biology have appeared in recent years and systems theory, the study of organisation and behaviour per se, is indeed a natural conceptual framework for such a task. This is, however, not the first time that systems theory has been applied in modelling cellular processes. Notably in the 1960s systems theory and biology enjoyed considerable interest among eminent scientists, mathematicians and engineers. Why did these early attempts vanish from research agendas? Here we shall review the domain of systems theory, its application to biology and the lessons that can be learned from the work of Robert Rosen. Rosen emerged from the early developments in the 1960s as a main critic but also developed a new alternative perspective to living systems, a concept that deserves a fresh look in the post-genome era of bioinformatics.

  15. Reliability analysis applied to structural tests

    NASA Technical Reports Server (NTRS)

    Diamond, P.; Payne, A. O.

    1972-01-01

    The application of reliability theory to predict, from structural fatigue test data, the risk of failure of a structure under service conditions because its load-carrying capability is progressively reduced by the extension of a fatigue crack, is considered. The procedure is applicable to both safe-life and fail-safe structures and, for a prescribed safety level, it will enable an inspection procedure to be planned or, if inspection is not feasible, it will evaluate the life to replacement. The theory has been further developed to cope with the case of structures with initial cracks, such as can occur in modern high-strength materials which are susceptible to the formation of small flaws during the production process. The method has been applied to a structure of high-strength steel and the results are compared with those obtained by the current life estimation procedures. This has shown that the conventional methods can be unconservative in certain cases, depending on the characteristics of the structure and the design operating conditions. The suitability of the probabilistic approach to the interpretation of the results from full-scale fatigue testing of aircraft structures is discussed and the assumptions involved are examined.

  16. 3RD Symposium on Applied Surface Analysis.

    DTIC Science & Technology

    1982-03-01

    lithium -- a condition which occurs during under-potential discharge. The surface studies of lithium on carbon showed lithium to be much more mobile in...of surface chemistry. The talk will begin with a summary of results for carbon monoxide chemisorbed on supported Rh as studied by transmission... lithium anode and the high surface-area Shawinigan Black current collector of the Li-LiAsF6 -AN-SO2 battery system have been ana- lyzed by XPS, SAM and

  17. Scanning methods applied to bitemark analysis

    NASA Astrophysics Data System (ADS)

    Bush, Peter J.; Bush, Mary A.

    2010-06-01

    The 2009 National Academy of Sciences report on forensics focused criticism on pattern evidence subdisciplines in which statements of unique identity are utilized. One principle of bitemark analysis is that the human dentition is unique to the extent that a perpetrator may be identified based on dental traits in a bitemark. Optical and electron scanning methods were used to measure dental minutia and to investigate replication of detail in human skin. Results indicated that being a visco-elastic substrate, skin effectively reduces the resolution of measurement of dental detail. Conclusions indicate caution in individualization statements.

  18. Multivariate analysis applied to tomato hybrid production.

    PubMed

    Balasch, S; Nuez, F; Palomares, G; Cuartero, J

    1984-11-01

    Twenty characters were measured on 60 tomato varieties cultivated in the open-air and in polyethylene plastic-house. Data were analyzed by means of principal components, factorial discriminant methods, Mahalanobis D(2) distances and principal coordinate techniques. Factorial discriminant and Mahalanobis D(2) distances methods, both of which require collecting data plant by plant, lead to similar conclusions as the principal components method that only requires taking data by plots. Characters that make up the principal components in both environments studied are the same, although the relative importance of each one of them varies within the principal components. By combining information supplied by multivariate analysis with the inheritance mode of characters, crossings among cultivars can be experimented with that will produce heterotic hybrids showing characters within previously established limits.

  19. Hypercube Expert System Shell - Applying Production Parallelism.

    DTIC Science & Technology

    1989-12-01

    3 I~~i rst and foreino l AFA L un covered t h ough literatutre reviews that efforts to ap- plY traditional soft ware inienentation methods to...ogete via )ase o ie Aprac set o tAiN) fihe l ts. Tche k nownelg a.,; l Post Oce pfacitess foloe aei es o ilal fa on t ria hi i I sessions angnde...Systems." In Proceedings of the National Conftrcnc on Artificial lntdlligenc (To Appear), August 1988. 17. Gupta, Anoop, Milind Tambe, Dirk Kalp

  20. Rotary spectra analysis applied to static stabilometry.

    PubMed

    Chiaramello, E; Knaflitz, M; Agostini, V

    2011-01-01

    Static stabilometry is a technique aimed at quantifying postural sway during quiet standing in the upright position. Many different models and many different techniques to analyze the trajectories of the Centre of Pressure (CoP) have been proposed. Most of the parameters calculated according to these different approaches are affected by a relevant intra- and inter-subject variability or do not have a clear physiological interpretation. In this study we hypothesize that CoP trajectories have rotational characteristics, therefore we decompose them in clockwise and counter-clockwise components, using the rotary spectra analysis. Rotary spectra obtained studying a population of healthy subjects are described through the group average of spectral parameters, i.e., 95% spectral bandwidth, mean frequency, median frequency, and skewness. Results are reported for the clockwise and the counter-clockwise components and refer to the upright position maintained with eyes open or closed. This study demonstrates that the approach is feasible and that some of the spectral parameters are statistically different between the open and closed eyes conditions. More research is needed to demonstrate the clinical applicability of this approach, but results so far obtained are promising.

  1. Digital Systems Analysis

    ERIC Educational Resources Information Center

    Martin, Vance S.

    2009-01-01

    There have been many attempts to understand how the Internet affects our modern world. There have also been numerous attempts to understand specific areas of the Internet. This article applies Immanuel Wallerstein's World Systems Analysis to our informationalist society. Understanding this world as divided among individual core, semi-periphery,…

  2. Treatment Integrity in Applied Behavior Analysis with Children.

    ERIC Educational Resources Information Center

    Gresham, Frank M.; And Others

    1993-01-01

    A review of 158 applied behavior analysis studies with children as subjects, published in the "Journal of Applied Behavior Analysis" between 1980 and 1990, found that (1) 16% measured the accuracy of independent variable implementation, and (2) two-thirds did not operationally define components of the independent variable. Specific recommendations…

  3. Compatibility of person-centered planning and applied behavior analysis

    PubMed Central

    Holburn, Steve

    2001-01-01

    In response to Osborne (1999), the aims and practices of person-centered planning (PCP) are compared to the basic principles of applied behavior analysis set forth by Baer, Wolf, and Risley (1968, 1987). The principal goal of PCP is social integration of people with disabilities; it qualifies as a socially important behavior, and its problems have been displayed sufficiently. However, social integration is a complex social problem whose solution requires access to system contingencies that influence lifestyles. Nearly all of the component goals of PCP proposed by O'Brien (1987b) have been reliably quantified, although concurrent measurement of outcomes such as friendship, autonomy, and respect presents a formidable challenge. Behavioral principles such as contingency and contextual control are operative within PCP, but problems in achieving reliable implementation appear to impede an experimental analysis. PMID:22478371

  4. Sensitivity analysis applied to stalled airfoil wake and steady control

    NASA Astrophysics Data System (ADS)

    Patino, Gustavo; Gioria, Rafael; Meneghini, Julio

    2014-11-01

    The sensitivity of an eigenvalue to base flow modifications induced by an external force is applied to the global unstable modes associated to the onset of vortex shedding in the wake of a stalled airfoil. In this work, the flow regime is close to the first instability of the system and its associated eigenvalue/eigenmode is determined. The sensitivity analysis to a general punctual external force allows establishing the regions where control devices must be in order to stabilize the global modes. Different types of steady control devices, passive and active, are used in the regions predicted by the sensitivity analysis to check the vortex shedding suppression, i.e. the primary instability bifurcation is delayed. The new eigenvalue, modified by the action of the device, is also calculated. Finally the spectral finite element method is employed to determine flow characteristics before and after of the bifurcation in order to cross check the results.

  5. Design of the optocoupler applied to medical lighting systems.

    PubMed

    Yang, Xibin; Lit, Rui; Zhu, Jianfeng; Xiong, Daxi

    2012-12-01

    A new type of optocoupler applied to medical lighting system is proposed, and the principle, Etendue and design process is introduced. With the help of Tracrpro, modeling and simulation of the optocoupler is conducted and the parameters are optimized. Analysis of factors affecting the energy coupling efficiency is done. With a view towards the development of Ultra High Brightness Light Emitting Diodes (UHB-LEDs), which play an important role a new sources of lighting in various biomedical devices, including those used in diagnosis and treatment, a series of simulations are executed and a variety of solutions are achieved. According to simulation results, the design target of coupling efficiency is achieved and the optical uniformity is also significantly improved. According to the result of theoretical analysis, verification experiments are designed and simulation results are verified. The optocoupler, which has simple structure, compact size and low cost, is suitable for applications in the field of low-cost medical domain.

  6. Applying machine learning techniques to DNA sequence analysis

    SciTech Connect

    Shavlik, J.W.

    1992-01-01

    We are developing a machine learning system that modifies existing knowledge about specific types of biological sequences. It does this by considering sample members and nonmembers of the sequence motif being learned. Using this information (which we call a domain theory''), our learning algorithm produces a more accurate representation of the knowledge needed to categorize future sequences. Specifically, the KBANN algorithm maps inference rules, such as consensus sequences, into a neural (connectionist) network. Neural network training techniques then use the training examples of refine these inference rules. We have been applying this approach to several problems in DNA sequence analysis and have also been extending the capabilities of our learning system along several dimensions.

  7. Applying machine learning techniques to DNA sequence analysis

    SciTech Connect

    Shavlik, J.W. . Dept. of Computer Sciences); Noordewier, M.O. . Dept. of Computer Science)

    1992-01-01

    We are primarily developing a machine teaming (ML) system that modifies existing knowledge about specific types of biological sequences. It does this by considering sample members and nonmembers of the sequence motif being teamed. Using this information, our teaming algorithm produces a more accurate representation of the knowledge needed to categorize future sequences. Specifically, our KBANN algorithm maps inference rules about a given recognition task into a neural network. Neural network training techniques then use the training examples to refine these inference rules. We call these rules a domain theory, following the convention in the machine teaming community. We have been applying this approach to several problems in DNA sequence analysis. In addition, we have been extending the capabilities of our teaming system along several dimensions. We have also been investigating parallel algorithms that perform sequence alignments in the presence of frameshift errors.

  8. Hyperspectral imaging applied to complex particulate solids systems

    NASA Astrophysics Data System (ADS)

    Bonifazi, Giuseppe; Serranti, Silvia

    2008-04-01

    HyperSpectral Imaging (HSI) is based on the utilization of an integrated hardware and software (HW&SW) platform embedding conventional imaging and spectroscopy to attain both spatial and spectral information from an object. Although HSI was originally developed for remote sensing, it has recently emerged as a powerful process analytical tool, for non-destructive analysis, in many research and industrial sectors. The possibility to apply on-line HSI based techniques in order to identify and quantify specific particulate solid systems characteristics is presented and critically evaluated. The originally developed HSI based logics can be profitably applied in order to develop fast, reliable and lowcost strategies for: i) quality control of particulate products that must comply with specific chemical, physical and biological constraints, ii) performance evaluation of manufacturing strategies related to processing chains and/or realtime tuning of operative variables and iii) classification-sorting actions addressed to recognize and separate different particulate solid products. Case studies, related to recent advances in the application of HSI to different industrial sectors, as agriculture, food, pharmaceuticals, solid waste handling and recycling, etc. and addressed to specific goals as contaminant detection, defect identification, constituent analysis and quality evaluation are described, according to authors' originally developed application.

  9. Setting events in applied behavior analysis: Toward a conceptual and methodological expansion

    PubMed Central

    Wahler, Robert G.; Fox, James J.

    1981-01-01

    The contributions of applied behavior analysis as a natural science approach to the study of human behavior are acknowledged. However, it is also argued that applied behavior analysis has provided limited access to the full range of environmental events that influence socially significant behavior. Recent changes in applied behavior analysis to include analysis of side effects and social validation represent ways in which the traditional applied behavior analysis conceptual and methodological model has been profitably expanded. A third area of expansion, the analysis of setting events, is proposed by the authors. The historical development of setting events as a behavior influence concept is traced. Modifications of the basic applied behavior analysis methodology and conceptual systems that seem necessary to setting event analysis are discussed and examples of descriptive and experimental setting event analyses are presented. PMID:16795646

  10. A Vision for Systems Engineering Applied to Wind Energy (Presentation)

    SciTech Connect

    Felker, F.; Dykes, K.

    2015-01-01

    This presentation was given at the Third Wind Energy Systems Engineering Workshop on January 14, 2015. Topics covered include the importance of systems engineering, a vision for systems engineering as applied to wind energy, and application of systems engineering approaches to wind energy research and development.

  11. Applying expertise to data in the Geologist's Assistant expert system

    SciTech Connect

    Berkbigler, K.P.; Papcun, G.J.; Marusak, N.L.; Hutson, J.E.

    1988-01-01

    The Geologist's Assistant combines expert system technology with numerical pattern-matching and online communication to a large database. This paper discusses the types of rules used for the expert system, the pattern-matching technique applied, and the implementation of the system using a commercial expert system development environment. 13 refs., 8 figs.

  12. Negative reinforcement in applied behavior analysis: an emerging technology.

    PubMed

    Iwata, B A

    1987-01-01

    Although the effects of negative reinforcement on human behavior have been studied for a number of years, a comprehensive body of applied research does not exist at this time. This article describes three aspects of negative reinforcement as it relates to applied behavior analysis: behavior acquired or maintained through negative reinforcement, the treatment of negatively reinforced behavior, and negative reinforcement as therapy. A consideration of research currently being done in these areas suggests the emergence of an applied technology on negative reinforcement.

  13. Negative Reinforcement in Applied Behavior Analysis: An Emerging Technology.

    ERIC Educational Resources Information Center

    Iwata, Brian A.

    1987-01-01

    The article describes three aspects of negative reinforcement as it relates to applied behavior analysis: behavior acquired or maintained through negative reinforcement, the treatment of negatively reinforced behavior, and negative reinforcement as therapy. Current research suggests the emergence of an applied technology on negative reinforcement.…

  14. Animal Research in the "Journal of Applied Behavior Analysis"

    ERIC Educational Resources Information Center

    Edwards, Timothy L.; Poling, Alan

    2011-01-01

    This review summarizes the 6 studies with nonhuman animal subjects that have appeared in the "Journal of Applied Behavior Analysis" and offers suggestions for future research in this area. Two of the reviewed articles described translational research in which pigeons were used to illustrate and examine behavioral phenomena of applied significance…

  15. B. F. Skinner's contributions to applied behavior analysis

    PubMed Central

    Morris, Edward K.; Smith, Nathaniel G.; Altus, Deborah E.

    2005-01-01

    Our paper reviews and analyzes B. F. Skinner's contributions to applied behavior analysis in order to assess his role as the field's originator and founder. We found, first, that his contributions fall into five categorizes: the style and content of his science, his interpretations of typical and atypical human behavior, the implications he drew from his science for application, his descriptions of possible applications, and his own applications to nonhuman and human behavior. Second, we found that he explicitly or implicitly addressed all seven dimensions of applied behavior analysis. These contributions and the dimensions notwithstanding, he neither incorporated the field's scientific (e.g., analytic) and social dimensions (e.g., applied) into any program of published research such that he was its originator, nor did he systematically integrate, advance, and promote the dimensions so to have been its founder. As the founder of behavior analysis, however, he was the father of applied behavior analysis. PMID:22478444

  16. Multidisciplinary System Reliability Analysis

    NASA Technical Reports Server (NTRS)

    Mahadevan, Sankaran; Han, Song; Chamis, Christos C. (Technical Monitor)

    2001-01-01

    The objective of this study is to develop a new methodology for estimating the reliability of engineering systems that encompass multiple disciplines. The methodology is formulated in the context of the NESSUS probabilistic structural analysis code, developed under the leadership of NASA Glenn Research Center. The NESSUS code has been successfully applied to the reliability estimation of a variety of structural engineering systems. This study examines whether the features of NESSUS could be used to investigate the reliability of systems in other disciplines such as heat transfer, fluid mechanics, electrical circuits etc., without considerable programming effort specific to each discipline. In this study, the mechanical equivalence between system behavior models in different disciplines are investigated to achieve this objective. A new methodology is presented for the analysis of heat transfer, fluid flow, and electrical circuit problems using the structural analysis routines within NESSUS, by utilizing the equivalence between the computational quantities in different disciplines. This technique is integrated with the fast probability integration and system reliability techniques within the NESSUS code, to successfully compute the system reliability of multidisciplinary systems. Traditional as well as progressive failure analysis methods for system reliability estimation are demonstrated, through a numerical example of a heat exchanger system involving failure modes in structural, heat transfer and fluid flow disciplines.

  17. First Attempt of Applying Factor Analysis in Moving Base Gravimetry

    NASA Astrophysics Data System (ADS)

    Li, X.; Roman, D. R.

    2014-12-01

    For gravimetric observation systems on mobile platforms (land/sea/airborne), the Low Signal to Noise Ratio (SNR) issue is the main barrier to achieving an accurate, high resolution gravity signal. Normally, low-pass filters (Childers et al 1999, Forsberg et al 2000, Kwon and Jekeli 2000, Hwang et al 2006) are applied to smooth or remove the high frequency "noise" - even though some of the high frequency component is not necessarily noise. This is especially true for aerogravity surveys such as those from the Gravity for the Redefinition of the American Vertical Datum (GRAV-D) project. These gravity survey flights have a spatial resolution of 10 km between tracks but higher resolution along track. The along track resolution is improved due to the lower flight height (6.1 km), equipment sensitivity, and improved modeling of potential errors. Additionally, these surveys suffer from a loss of signal power due to the increased flight elevation. Hence, application of a low-pass filter removes possible signal sensed in the along-track direction that might otherwise prove useful for various geophysical and geodetic applications. Some cutting-edge developments in Wavelets and Artificial Neural Networks had been successfully applied for obtaining improved results (Li 2008 and 2011, Liang and Liu 2013). However, a clearer and fundamental understanding of the error characteristics will further improve the quality of the gravity estimates out of these gravimetric systems. Here, instead of using any predefined basis function or any a priori model, the idea of Factor Analysis is first employed to try to extract the underlying factors of the noises in the systems. Real data sets collected by both land vehicle and aircraft will be processed as the examples.

  18. Competing Uses of Underground Systems Related to Energy Supply: Applying Single- and Multiphase Simulations for Site Characterization and Risk-Analysis

    NASA Astrophysics Data System (ADS)

    Kissinger, A.; Walter, L.; Darcis, M.; Flemisch, B.; Class, H.

    2012-04-01

    Global climate change, shortage of resources and the resulting turn towards renewable sources of energy lead to a growing demand for the utilization of subsurface systems. Among these competing uses are Carbon Capture and Storage (CCS), geothermal energy, nuclear waste disposal, "renewable" methane or hydrogen storage as well as the ongoing production of fossil resources like oil, gas, and coal. Besides competing among themselves, these technologies may also create conflicts with essential public interests like water supply. For example, the injection of CO2 into the underground causes an increase in pressure reaching far beyond the actual radius of influence of the CO2 plume, potentially leading to large amounts of displaced salt water. Finding suitable sites is a demanding task for several reasons. Natural systems as opposed to technical systems are always characterized by heterogeneity. Therefore, parameter uncertainty impedes reliable predictions towards capacity and safety of a site. State of the art numerical simulations combined with stochastic approaches need to be used to obtain a more reliable assessment of the involved risks and the radii of influence of the different processes. These simulations may include the modeling of single- and multiphase non-isothermal flow, geo-chemical and geo-mechanical processes in order to describe all relevant physical processes adequately. Stochastic approaches have the aim to estimate a bandwidth of the key output parameters based on uncertain input parameters. Risks for these different underground uses can then be made comparable with each other. Along with the importance and the urgency of the competing processes this may lead to a more profound basis for a decision. Communicating risks to stake holders and a concerned public is crucial for the success of finding a suitable site for CCS (or other subsurface utilization). We present and discuss first steps towards an approach for addressing the issue of competitive

  19. Causal Claims and the Operational Environment: An Analysis of Conventional and Emergent Causality as Applied to the Systems in 2007-2008 Iraq

    DTIC Science & Technology

    2012-06-08

    possesses a sense of agency or free-will and is capable of changing or adapting. That is to say they that, “organizations are strongly influenced by...increasing cooperation throughout their time in that area. Both of these systems have a sense of agency , read free-will, that enables them to choose whether... sense of agency which allows it to operate on its own as would a living, breathing human being. Third, I give an explanation of each open system’s

  20. Overview of MSFC's Applied Fluid Dynamics Analysis Group Activities

    NASA Technical Reports Server (NTRS)

    Garcia, Roberto; Griffin, Lisa; Williams, Robert

    2003-01-01

    TD64, the Applied Fluid Dynamics Analysis Group, is one of several groups with high-fidelity fluids design and analysis expertise in the Space Transportation Directorate at Marshall Space Flight Center (MSFC). TD64 assists personnel working on other programs. The group participates in projects in the following areas: turbomachinery activities, nozzle activities, combustion devices, and the Columbia accident investigation.

  1. The Significance of Regional Analysis in Applied Geography.

    ERIC Educational Resources Information Center

    Sommers, Lawrence M.

    Regional analysis is central to applied geographic research, contributing to better planning and policy development for a variety of societal problems facing the United States. The development of energy policy serves as an illustration of the capabilities of this type of analysis. The United States has had little success in formulating a national…

  2. Extended Kramers-Moyal analysis applied to optical trapping.

    PubMed

    Honisch, Christoph; Friedrich, Rudolf; Hörner, Florian; Denz, Cornelia

    2012-08-01

    The Kramers-Moyal analysis is a well-established approach to analyze stochastic time series from complex systems. If the sampling interval of a measured time series is too low, systematic errors occur in the analysis results. These errors are labeled as finite time effects in the literature. In the present article, we present some new insights about these effects and discuss the limitations of a previously published method to estimate Kramers-Moyal coefficients at the presence of finite time effects. To increase the reliability of this method and to avoid misinterpretations, we extend it by the computation of error estimates for estimated parameters using a Monte Carlo error propagation technique. Finally, the extended method is applied to a data set of an optical trapping experiment yielding estimations of the forces acting on a Brownian particle trapped by optical tweezers. We find an increased Markov-Einstein time scale of the order of the relaxation time of the process, which can be traced back to memory effects caused by the interaction of the particle and the fluid. Above the Markov-Einstein time scale, the process can be very well described by the classical overdamped Markov model for Brownian motion.

  3. Research in Applied Mathematics Related to Nonlinear System Theory.

    DTIC Science & Technology

    1981-09-01

    control systems", Journal of Mathematical Analysis and Applications , 58: 98-112. R. E. KALMAN [1976] "Realization theory of linear dynamical systems...Theory. [19801 "Some remarks on the reachability of infinite- dimensional linear systems", Journal of Mathematical Analysis and Applications , 74: 568-577

  4. Quantitative Analysis of the Interdisciplinarity of Applied Mathematics.

    PubMed

    Xie, Zheng; Duan, Xiaojun; Ouyang, Zhenzheng; Zhang, Pengyuan

    2015-01-01

    The increasing use of mathematical techniques in scientific research leads to the interdisciplinarity of applied mathematics. This viewpoint is validated quantitatively here by statistical and network analysis on the corpus PNAS 1999-2013. A network describing the interdisciplinary relationships between disciplines in a panoramic view is built based on the corpus. Specific network indicators show the hub role of applied mathematics in interdisciplinary research. The statistical analysis on the corpus content finds that algorithms, a primary topic of applied mathematics, positively correlates, increasingly co-occurs, and has an equilibrium relationship in the long-run with certain typical research paradigms and methodologies. The finding can be understood as an intrinsic cause of the interdisciplinarity of applied mathematics.

  5. Quantitative Analysis of the Interdisciplinarity of Applied Mathematics

    PubMed Central

    Zhang, Pengyuan

    2015-01-01

    The increasing use of mathematical techniques in scientific research leads to the interdisciplinarity of applied mathematics. This viewpoint is validated quantitatively here by statistical and network analysis on the corpus PNAS 1999–2013. A network describing the interdisciplinary relationships between disciplines in a panoramic view is built based on the corpus. Specific network indicators show the hub role of applied mathematics in interdisciplinary research. The statistical analysis on the corpus content finds that algorithms, a primary topic of applied mathematics, positively correlates, increasingly co-occurs, and has an equilibrium relationship in the long-run with certain typical research paradigms and methodologies. The finding can be understood as an intrinsic cause of the interdisciplinarity of applied mathematics. PMID:26352604

  6. Development of adaptive control applied to chaotic systems

    NASA Astrophysics Data System (ADS)

    Rhode, Martin Andreas

    1997-12-01

    Continuous-time derivative control and adaptive map-based recursive feedback control techniques are used to control chaos in a variety of systems and in situations that are of practical interest. The theoretical part of the research includes the review of fundamental concept of control theory in the context of its applications to deterministic chaotic systems, the development of a new adaptive algorithm to identify the linear system properties necessary for control, and the extension of the recursive proportional feedback control technique, RPF, to high dimensional systems. Chaos control was applied to models of a thermal pulsed combustor, electro-chemical dissolution and the hyperchaotic Rossler system. Important implications for combustion engineering were suggested by successful control of the model of the thermal pulsed combustor. The system was automatically tracked while maintaining control into regions of parameter and state space where no stable attractors exist. In a simulation of the electrochemical dissolution system, application of derivative control to stabilize a steady state, and adaptive RPF to stabilize a period one orbit, was demonstrated. The high dimensional adaptive control algorithm was applied in a simulation using the Rossler hyperchaotic system, where a period-two orbit with two unstable directions was stabilized and tracked over a wide range of a system parameter. In the experimental part, the electrochemical system was studied in parameter space, by scanning the applied potential and the frequency of the rotating copper disk. The automated control algorithm is demonstrated to be effective when applied to stabilize a period-one orbit in the experiment. We show the necessity of small random perturbations applied to the system in order to both learn the dynamics and control the system at the same time. The simultaneous learning and control capability is shown to be an important part of the active feedback control.

  7. Factorial switching linear dynamical systems applied to physiological condition monitoring.

    PubMed

    Quinn, John A; Williams, Christopher K I; McIntosh, Neil

    2009-09-01

    Condition monitoring often involves the analysis of systems with hidden factors that switch between different modes of operation in some way. Given a sequence of observations, the task is to infer the filtering distribution of the switch setting at each time step. In this paper, we present factorial switching linear dynamical systems as a general framework for handling such problems. We show how domain knowledge and learning can be successfully combined in this framework, and introduce a new factor (the "X-factor") for dealing with unmodeled variation. We demonstrate the flexibility of this type of model by applying it to the problem of monitoring the condition of a premature baby receiving intensive care. The state of health of a baby cannot be observed directly, but different underlying factors are associated with particular patterns of physiological measurements and artifacts. We have explicit knowledge of common factors and use the X-factor to model novel patterns which are clinically significant but have unknown cause. Experimental results are given which show the developed methods to be effective on typical intensive care unit monitoring data.

  8. System theory as applied differential geometry. [linear system

    NASA Technical Reports Server (NTRS)

    Hermann, R.

    1979-01-01

    The invariants of input-output systems under the action of the feedback group was examined. The approach used the theory of Lie groups and concepts of modern differential geometry, and illustrated how the latter provides a basis for the discussion of the analytic structure of systems. Finite dimensional linear systems in a single independent variable are considered. Lessons of more general situations (e.g., distributed parameter and multidimensional systems) which are increasingly encountered as technology advances are presented.

  9. Complex, Dynamic Systems: A New Transdisciplinary Theme for Applied Linguistics?

    ERIC Educational Resources Information Center

    Larsen-Freeman, Diane

    2012-01-01

    In this plenary address, I suggest that Complexity Theory has the potential to contribute a transdisciplinary theme to applied linguistics. Transdisciplinary themes supersede disciplines and spur new kinds of creative activity (Halliday 2001 [1990]). Investigating complex systems requires researchers to pay attention to system dynamics. Since…

  10. Applied behavior analysis: New directions from the laboratory

    PubMed Central

    Epling, W. Frank; Pierce, W. David

    1983-01-01

    Applied behavior analysis began when laboratory based principles were extended to humans inorder to change socially significant behavior. Recent laboratory findings may have applied relevance; however, the majority of basic researchers have not clearly communicated the practical implications of their work. The present paper samples some of the new findings and attempts to demonstrate their applied importance. Schedule-induced behavior which occurs as a by-product of contingencies of reinforcement is discussed. Possible difficulties in treatment and management of induced behaviors are considered. Next, the correlation-based law of effect and the implications of relative reinforcement are explored in terms of applied examples. Relative rate of reinforcement is then extended to the literature dealing with concurrent operants. Concurrent operant models may describe human behavior of applied importance, and several techniques for modification of problem behavior are suggested. As a final concern, the paper discusses several new paradigms. While the practical importance of these models is not clear at the moment, it may be that new practical advantages will soon arise. Thus, it is argued that basic research continues to be of theoretical and practical importance to applied behavior analysis. PMID:22478574

  11. Overview of MSFC's Applied Fluid Dynamics Analysis Group Activities

    NASA Technical Reports Server (NTRS)

    Garcia, Roberto; Wang, Tee-See; Griffin, Lisa; Turner, James E. (Technical Monitor)

    2001-01-01

    This document is a presentation graphic which reviews the activities of the Applied Fluid Dynamics Analysis Group at Marshall Space Flight Center (i.e., Code TD64). The work of this group focused on supporting the space transportation programs. The work of the group is in Computational Fluid Dynamic tool development. This development is driven by hardware design needs. The major applications for the design and analysis tools are: turbines, pumps, propulsion-to-airframe integration, and combustion devices.

  12. Animal research in the Journal of Applied Behavior Analysis.

    PubMed

    Edwards, Timothy L; Poling, Alan

    2011-01-01

    This review summarizes the 6 studies with nonhuman animal subjects that have appeared in the Journal of Applied Behavior Analysis and offers suggestions for future research in this area. Two of the reviewed articles described translational research in which pigeons were used to illustrate and examine behavioral phenomena of applied significance (say-do correspondence and fluency), 3 described interventions that changed animals' behavior (self-injury by a baboon, feces throwing and spitting by a chimpanzee, and unsafe trailer entry by horses) in ways that benefited the animals and the people in charge of them, and 1 described the use of trained rats that performed a service to humans (land-mine detection). We suggest that each of these general research areas merits further attention and that the Journal of Applied Behavior Analysis is an appropriate outlet for some of these publications.

  13. Applying systems engineering methodologies to the micro- and nanoscale realm

    NASA Astrophysics Data System (ADS)

    Garrison Darrin, M. Ann

    2012-06-01

    Micro scale and nano scale technology developments have the potential to revolutionize smart and small systems. The application of systems engineering methodologies that integrate standalone, small-scale technologies and interface them with macro technologies to build useful systems is critical to realizing the potential of these technologies. This paper covers the expanding knowledge base on systems engineering principles for micro and nano technology integration starting with a discussion of the drivers for applying a systems approach. Technology development on the micro and nano scale has transition from laboratory curiosity to the realization of products in the health, automotive, aerospace, communication, and numerous other arenas. This paper focuses on the maturity (or lack thereof) of the field of nanosystems which is emerging in a third generation having transitioned from completing active structures to creating systems. The emphasis of applying a systems approach focuses on successful technology development based on the lack of maturity of current nano scale systems. Therefore the discussion includes details relating to enabling roles such as product systems engineering and technology development. Classical roles such as acquisition systems engineering are not covered. The results are also targeted towards small-scale technology developers who need to take into account systems engineering processes such as requirements definition, verification, and validation interface management and risk management in the concept phase of technology development to maximize the likelihood of success, cost effective micro and nano technology to increase the capability of emerging deployed systems and long-term growth and profits.

  14. Applying Model Based Systems Engineering to NASA's Space Communications Networks

    NASA Technical Reports Server (NTRS)

    Bhasin, Kul; Barnes, Patrick; Reinert, Jessica; Golden, Bert

    2013-01-01

    System engineering practices for complex systems and networks now require that requirement, architecture, and concept of operations product development teams, simultaneously harmonize their activities to provide timely, useful and cost-effective products. When dealing with complex systems of systems, traditional systems engineering methodology quickly falls short of achieving project objectives. This approach is encumbered by the use of a number of disparate hardware and software tools, spreadsheets and documents to grasp the concept of the network design and operation. In case of NASA's space communication networks, since the networks are geographically distributed, and so are its subject matter experts, the team is challenged to create a common language and tools to produce its products. Using Model Based Systems Engineering methods and tools allows for a unified representation of the system in a model that enables a highly related level of detail. To date, Program System Engineering (PSE) team has been able to model each network from their top-level operational activities and system functions down to the atomic level through relational modeling decomposition. These models allow for a better understanding of the relationships between NASA's stakeholders, internal organizations, and impacts to all related entities due to integration and sustainment of existing systems. Understanding the existing systems is essential to accurate and detailed study of integration options being considered. In this paper, we identify the challenges the PSE team faced in its quest to unify complex legacy space communications networks and their operational processes. We describe the initial approaches undertaken and the evolution toward model based system engineering applied to produce Space Communication and Navigation (SCaN) PSE products. We will demonstrate the practice of Model Based System Engineering applied to integrating space communication networks and the summary of its

  15. B. F. Skinner's Contributions to Applied Behavior Analysis

    ERIC Educational Resources Information Center

    Morris, Edward K.; Smith, Nathaniel G.; Altus, Deborah E.

    2005-01-01

    Our paper reviews and analyzes B. F. Skinner's contributions to applied behavior analysis in order to assess his role as the field's originator and founder. We found, first, that his contributions fall into five categorizes: the style and content of his science, his interpretations of typical and atypical human behavior, the implications he drew…

  16. Positive Behavior Support and Applied Behavior Analysis: A Familial Alliance

    ERIC Educational Resources Information Center

    Dunlap, Glen; Carr, Edward G.; Horner, Robert H.; Zarcone, Jennifer R.; Schwartz, Ilene

    2008-01-01

    Positive behavior support (PBS) emerged in the mid-1980s as an approach for understanding and addressing problem behaviors. PBS was derived primarily from applied behavior analysis (ABA). Over time, however, PBS research and practice has incorporated evaluative methods, assessment and intervention procedures, and conceptual perspectives associated…

  17. Progressive-Ratio Schedules and Applied Behavior Analysis

    ERIC Educational Resources Information Center

    Poling, Alan

    2010-01-01

    Establishing appropriate relations between the basic and applied areas of behavior analysis has been of long and persistent interest to the author. In this article, the author illustrates that there is a direct relation between how hard an organism will work for access to an object or activity, as indexed by the largest ratio completed under a…

  18. Overview af MSFC's Applied Fluid Dynamics Analysis Group Activities

    NASA Technical Reports Server (NTRS)

    Garcia, Roberto; Griffin, Lisa; Williams, Robert

    2004-01-01

    This paper presents viewgraphs on NASA Marshall Space Flight Center's Applied Fluid Dynamics Analysis Group Activities. The topics include: 1) Status of programs at MSFC; 2) Fluid Mechanics at MSFC; 3) Relevant Fluid Dynamics Activities at MSFC; and 4) Shuttle Return to Flight.

  19. Applied Behavior Analysis Is a Science And, Therefore, Progressive

    ERIC Educational Resources Information Center

    Leaf, Justin B.; Leaf, Ronald; McEachin, John; Taubman, Mitchell; Ala'i-Rosales, Shahla; Ross, Robert K.; Smith, Tristram; Weiss, Mary Jane

    2016-01-01

    Applied behavior analysis (ABA) is a science and, therefore, involves progressive approaches and outcomes. In this commentary we argue that the spirit and the method of science should be maintained in order to avoid reductionist procedures, stifled innovation, and rote, unresponsive protocols that become increasingly removed from meaningful…

  20. Support systems design and analysis

    NASA Technical Reports Server (NTRS)

    Ferguson, R. M.

    1985-01-01

    The integration of Kennedy Space Center (KSC) ground support systems with the new launch processing system and new launch vehicle provided KSC with a unique challenge in system design and analysis for the Space Transportation System. Approximately 70 support systems are controlled and monitored by the launch processing system. Typical systems are main propulsion oxygen and hydrogen loading systems, environmental control life support system, hydraulics, etc. An End-to-End concept of documentation and analysis was chosen and applied to these systems. Unique problems were resolved in the areas of software analysis, safing under emergency conditions, sampling rates, and control loop analysis. New methods of performing End-to-End reliability analyses were implemented. The systems design approach selected and the resolution of major problem areas are discussed.

  1. Applying Sustainable Systems Development Approach to Educational Technology Systems

    ERIC Educational Resources Information Center

    Huang, Albert

    2012-01-01

    Information technology (IT) is an essential part of modern education. The roles and contributions of technology to education have been thoroughly documented in academic and professional literature. Despite the benefits, the use of educational technology systems (ETS) also creates a significant impact on the environment, primarily due to energy…

  2. Recent reinforcement-schedule research and applied behavior analysis

    PubMed Central

    Lattal, Kennon A.; Neef, Nancy A.

    1996-01-01

    Reinforcement schedules are considered in relation to applied behavior analysis by examining several recent laboratory experiments with humans and other animals. The experiments are drawn from three areas of contemporary schedule research: behavioral history effects on schedule performance, the role of instructions in schedule performance of humans, and dynamic schedules of reinforcement. All of the experiments are discussed in relation to the role of behavioral history in current schedule performance. The paper concludes by extracting from the experiments some more general issues concerning reinforcement schedules in applied research and practice. PMID:16795888

  3. Applied Information Systems Research Program (AISRP) Workshop 3 meeting proceedings

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The third Workshop of the Applied Laboratory Systems Research Program (AISRP) met at the Univeristy of Colorado's Laboratory for Atmospheric and Space Physics in August of 1993. The presentations were organized into four sessions: Artificial Intelligence Techniques; Scientific Visualization; Data Management and Archiving; and Research and Technology.

  4. Associate of Applied Science Degree in Office Systems. Proposal.

    ERIC Educational Resources Information Center

    Gallaudet Coll., Washington, DC. School of Preparatory Studies.

    This proposal culminates a 5-year study of the possibility of awarding associate degrees at Gallaudet College, a private, liberal arts college for hearing impaired adults. The proposal outlines an Associate of Applied Science degree (AAS) in Office Systems at the School of Preparatory Studies. First, introductory material provides a brief history…

  5. We Are Family: Applying Family Systems Theory to Classrooms.

    ERIC Educational Resources Information Center

    Braun, Joseph A., Jr.; Garrett, Joyce Lynn

    1988-01-01

    Describes how counselors can apply the family systems model to classrooms in helping teachers create a more open and effective climate. Discusses these strategies for implementation: basic communication and interpersonal skills, fairness conferences, classroom meetings, magic circle and circle of warmth, and role playing. (Author/ABL)

  6. Applying Technology Ranking and Systems Engineering in Advanced Life Support

    NASA Technical Reports Server (NTRS)

    Jones, Harry; Luna, Bernadette (Technical Monitor)

    2000-01-01

    According to the Advanced Life Support (ALS) Program Plan, the Systems Modeling and Analysis Project (SMAP) has two important tasks: 1) prioritizing investments in ALS Research and Technology Development (R&TD), and 2) guiding the evolution of ALS systems. Investments could be prioritized simply by independently ranking different technologies, but we should also consider a technology's impact on system design. Guiding future ALS systems will require SMAP to consider many aspects of systems engineering. R&TD investments can be prioritized using familiar methods for ranking technology. The first step is gathering data on technology performance, safety, readiness level, and cost. Then the technologies are ranked using metrics or by decision analysis using net present economic value. The R&TD portfolio can be optimized to provide the maximum expected payoff in the face of uncertain future events. But more is needed. The optimum ALS system can not be designed simply by selecting the best technology for each predefined subsystem. Incorporating a new technology, such as food plants, can change the specifications of other subsystems, such as air regeneration. Systems must be designed top-down starting from system objectives, not bottom-up from selected technologies. The familiar top-down systems engineering process includes defining mission objectives, mission design, system specification, technology analysis, preliminary design, and detail design. Technology selection is only one part of systems analysis and engineering, and it is strongly related to the subsystem definitions. ALS systems should be designed using top-down systems engineering. R&TD technology selection should consider how the technology affects ALS system design. Technology ranking is useful but it is only a small part of systems engineering.

  7. Recent results of nonlinear estimators applied to hereditary systems.

    NASA Technical Reports Server (NTRS)

    Schiess, J. R.; Roland, V. R.; Wells, W. R.

    1972-01-01

    An application of the extended Kalman filter to delayed systems to estimate the state and time delay is presented. Two nonlinear estimators are discussed and the results compared with those of the Kalman filter. For all the filters considered, the hereditary system was treated with the delay in the pure form and by using Pade approximations of the delay. A summary of the convergence properties of the filters studied is given. The results indicate that the linear filter applied to the delayed system performs inadequately while the nonlinear filters provide reasonable estimates of both the state and the parameters.

  8. Boston Society's 11th Annual Applied Pharmaceutical Analysis conference.

    PubMed

    Lee, Violet; Liu, Ang; Groeber, Elizabeth; Moghaddam, Mehran; Schiller, James; Tweed, Joseph A; Walker, Gregory S

    2016-02-01

    Boston Society's 11th Annual Applied Pharmaceutical Analysis conference, Hyatt Regency Hotel, Cambridge, MA, USA, 14-16 September 2015 The Boston Society's 11th Annual Applied Pharmaceutical Analysis (APA) conference took place at the Hyatt Regency hotel in Cambridge, MA, on 14-16 September 2015. The 3-day conference affords pharmaceutical professionals, academic researchers and industry regulators the opportunity to collectively participate in meaningful and relevant discussions impacting the areas of pharmaceutical drug development. The APA conference was organized in three workshops encompassing the disciplines of regulated bioanalysis, discovery bioanalysis (encompassing new and emerging technologies) and biotransformation. The conference included a short course titled 'Bioanalytical considerations for the clinical development of antibody-drug conjugates (ADCs)', an engaging poster session, several panel and round table discussions and over 50 diverse talks from leading industry and academic scientists.

  9. Developing an interdisciplinary master's program in applied behavior analysis

    PubMed Central

    Lowenkron, Barry; Mitchell, Lynda

    1995-01-01

    At many universities, faculty interested in behavior analysis are spread across disciplines. This makes difficult the development of behavior-analytically oriented programs, and impedes regular contact among colleagues who share common interests. However, this separation by disciplines can be a source of strength if it is used to develop interdisciplinary programs. In this article we describe how a bottom-up strategy was used to develop two complementary interdisciplinary MS programs in applied behavior analysis, and conclude with a description of the benefits—some obvious, some surprising—that can emerge from the development of such programs. PMID:22478230

  10. Circulation control technology applied to propulsive high lift systems

    NASA Technical Reports Server (NTRS)

    Englar, R. J.; Nichols, J. H., Jr.; Harris, M. J.; Eppel, J. C.; Shovlin, M. D.

    1984-01-01

    Technology developed for the Circulation Control Wing high-lift system has been extended to augment lift by entraining and redirecting engine thrust. Ejecting a thin jet sheet tangentially over a small curved deflecting surface adjacent to the slipstream of a turbofan engine causes the slipstream to flow around that deflecting surface. The angle of deflection is controlled pneumatically by varying the momentum of the thin jet sheet. The downward momentum of the slipstream enhances wing lift. This concept of pneumatically deflecting the slipstream has been applied to an upper surface blowing high-lift system and to a thrust deflecting system. The capability of the pneumatic upper surface blowing system was demonstrated in a series of investigations using a wind tunnel model and the NASA Quiet Short-haul Research Aircraft (QSRA). Full-scale thrust deflections greater than 90 deg were achieved. This mechanically simple system can provide increased maneuverability, heavy lift or overload capability, or short takeoff and landing performance.

  11. Nuclear safety as applied to space power reactor systems

    SciTech Connect

    Cummings, G.E.

    1987-01-01

    To develop a strategy for incorporating and demonstrating safety, it is necessary to enumerate the unique aspects of space power reactor systems from a safety standpoint. These features must be differentiated from terrestrial nuclear power plants so that our experience can be applied properly. Some ideas can then be developed on how safe designs can be achieved so that they are safe and perceived to be safe by the public. These ideas include operating only after achieving a stable orbit, developing an inherently safe design, ''designing'' in safety from the start and managing the system development (design) so that it is perceived safe. These and other ideas are explored further in this paper.

  12. Differential item functioning analysis by applying multiple comparison procedures.

    PubMed

    Eusebi, Paolo; Kreiner, Svend

    2015-01-01

    Analysis within a Rasch measurement framework aims at development of valid and objective test score. One requirement of both validity and objectivity is that items do not show evidence of differential item functioning (DIF). A number of procedures exist for the assessment of DIF including those based on analysis of contingency tables by Mantel-Haenszel tests and partial gamma coefficients. The aim of this paper is to illustrate Multiple Comparison Procedures (MCP) for analysis of DIF relative to a variable defining a very large number of groups, with an unclear ordering with respect to the DIF effect. We propose a single step procedure controlling the false discovery rate for DIF detection. The procedure applies for both dichotomous and polytomous items. In addition to providing evidence against a hypothesis of no DIF, the procedure also provides information on subset of groups that are homogeneous with respect to the DIF effect. A stepwise MCP procedure for this purpose is also introduced.

  13. Activity anorexia: An interplay between basic and applied behavior analysis.

    PubMed

    Pierce, W D; Epling, W F; Dews, P B; Estes, W K; Morse, W H; Van Orman, W; Herrnstein, R J

    1994-01-01

    The relationship between basic research with nonhumans and applied behavior analysis is illustrated by our work on activity anorexia. When rats are fed one meal a day and allowed to run on an activity wheel, they run excessively, stop eating, and die of starvation. Convergent evidence, from several different research areas, indicates that the behavior of these animals and humans who self-starve is functionally similar. A biobehavioral theory of activity anorexia is presented that details the cultural contingencies, behavioral processes, and physiology of anorexia. Diagnostic criteria and a three-stage treatment program for activity-based anorexia are outlined. The animal model permits basic research on anorexia that for practical and ethical reasons cannot be conducted with humans. Thus, basic research can have applied importance.

  14. Photoeletrolytic system applied to remazol red brilliant degradation.

    PubMed

    Sousa, Mariana Lopes; Moraes, Peterson Bueno; Bidoia, Ederio Dino

    2011-01-01

    Toxicity tests using Sacharomycces cerevisiae were made with simulated textile effluents containing reactive dye (remazol red brilliant) treated by photoeletrolytic process, varying treatment time and applied current. The treatment incorporated an electrolytic reactor with rectangular titanium anode coated with 70% TiO(2)/30% RuO(2) cathode and a rectangular stainless steel coupled with another photolytic reactor containing a high power UV lamp. The treatment system was used in batch recirculation, in other words, the simulated effluent was driven by the system through a helical pump. It was observed that the higher the value of current applied, the longer the treatment has greater color removal of textile effluent and higher mortality of S. cerevisiae, killing up to 100% of the cells at the end of the treatment. With a lower current applied and having the treatment time of 5 minutes, the effluent showed a color removal of 97% and a lower mortality of S. cerevisiae than the effluent simulated without any treatment.

  15. Cladistic analysis applied to the classification of volcanoes

    NASA Astrophysics Data System (ADS)

    Hone, D. W. E.; Mahony, S. H.; Sparks, R. S. J.; Martin, K. T.

    2007-11-01

    Cladistics is a systematic method of classification that groups entities on the basis of sharing similar characteristics in the most parsimonious manner. Here cladistics is applied to the classification of volcanoes using a dataset of 59 Quaternary volcanoes and 129 volcanic edifices of the Tohoku region, Northeast Japan. Volcano and edifice characteristics recorded in the database include attributes of volcano size, chemical composition, dominant eruptive products, volcano morphology, dominant landforms, volcano age and eruptive history. Without characteristics related to time the volcanic edifices divide into two groups, with characters related to volcano size, dominant composition and edifice morphology being the most diagnostic. Analysis including time based characteristics yields four groups with a good correlation between these groups and the two groups from the analysis without time for 108 out of 129 volcanic edifices. Thus when characters are slightly changed the volcanoes still form similar groupings. Analysis of the volcanoes both with and without time yields three groups based on compositional, eruptive products and morphological characters. Spatial clusters of volcanic centres have been recognised in the Tohoku region by Tamura et al. ( Earth Planet Sci Lett 197:105 106, 2002). The groups identified by cladistic analysis are distributed unevenly between the clusters, indicating a tendency for individual clusters to form similar kinds of volcanoes with distinctive but coherent styles of volcanism. Uneven distribution of volcano types between clusters can be explained by variations in dominant magma compositions through time, which are reflected in eruption products and volcanic landforms. Cladistic analysis can be a useful tool for elucidating dynamic igneous processes that could be applied to other regions and globally. Our exploratory study indicates that cladistics has promise as a method for classifying volcanoes and potentially elucidating dynamic

  16. Applying AI tools to operational space environmental analysis

    NASA Technical Reports Server (NTRS)

    Krajnak, Mike; Jesse, Lisa; Mucks, John

    1995-01-01

    The U.S. Air Force and National Oceanic Atmospheric Agency (NOAA) space environmental operations centers are facing increasingly complex challenges meeting the needs of their growing user community. These centers provide current space environmental information and short term forecasts of geomagnetic activity. Recent advances in modeling and data access have provided sophisticated tools for making accurate and timely forecasts, but have introduced new problems associated with handling and analyzing large quantities of complex data. AI (Artificial Intelligence) techniques have been considered as potential solutions to some of these problems. Fielding AI systems has proven more difficult than expected, in part because of operational constraints. Using systems which have been demonstrated successfully in the operational environment will provide a basis for a useful data fusion and analysis capability. Our approach uses a general purpose AI system already in operational use within the military intelligence community, called the Temporal Analysis System (TAS). TAS is an operational suite of tools supporting data processing, data visualization, historical analysis, situation assessment and predictive analysis. TAS includes expert system tools to analyze incoming events for indications of particular situations and predicts future activity. The expert system operates on a knowledge base of temporal patterns encoded using a knowledge representation called Temporal Transition Models (TTM's) and an event database maintained by the other TAS tools. The system also includes a robust knowledge acquisition and maintenance tool for creating TTM's using a graphical specification language. The ability to manipulate TTM's in a graphical format gives non-computer specialists an intuitive way of accessing and editing the knowledge base. To support space environmental analyses, we used TAS's ability to define domain specific event analysis abstractions. The prototype system defines

  17. Data Systems Task Analysis.

    DTIC Science & Technology

    1979-08-01

    A08873 MARINE CORPS WASHINGTON DC F/B 5/9 DATA SYSTEMS TASK ANALYSIS. (U) "CLASSIFIEO. -%mm . LEVELIs DATA SYSTEMS O0 TASK ANALYSIS DCI) OO JF AUG 28...TECI-NICIAN jl. CCMPUTER SYSTEMS EVALLATOR ,13. LCMPUTER SYSTEMS MANAGER 314. LCMPUTER SYSTEMS MCNITOR A5o LCMPUTER TERMINAL OPERATOR j16. LCNFIGURATION...OPERATOR )27. DATA PROCESSING NCO )28. DATA PROCESSINIG TECHNICIAN 329e DATA SYSTEMS LIBRARIAN )35* DATA SYSTEMS OPERATICNS Cl-IEF 331. DATA SYSTEMS

  18. Shape analysis applied in heavy ion reactions near Fermi energy

    NASA Astrophysics Data System (ADS)

    Zhang, S.; Huang, M.; Wada, R.; Liu, X.; Lin, W.; Wang, J.

    2017-03-01

    A new method is proposed to perform shape analyses and to evaluate their validity in heavy ion collisions near the Fermi energy. In order to avoid erroneous values of shape parameters in the calculation, a test particle method is utilized in which each nucleon is represented by n test particles, similar to that used in the Boltzmann–Uehling–Uhlenbeck (BUU) calculations. The method is applied to the events simulated by an antisymmetrized molecular dynamics model. The geometrical shape of fragments is reasonably extracted when n = 100 is used. A significant deformation is observed for all fragments created in the multifragmentation process. The method is also applied to the shape of the momentum distribution for event classification. In the momentum case, the errors in the eigenvalue calculation become much smaller than those of the geometrical shape analysis and the results become similar between those with and without the test particle method, indicating that in intermediate heavy ion collisions the shape analysis of momentum distribution can be used for the event classification without the test particle method.

  19. Applied Information Systems Research Program (AISRP). Workshop 2: Meeting Proceedings

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The Earth and space science participants were able to see where the current research can be applied in their disciplines and computer science participants could see potential areas for future application of computer and information systems research. The Earth and Space Science research proposals for the High Performance Computing and Communications (HPCC) program were under evaluation. Therefore, this effort was not discussed at the AISRP Workshop. OSSA's other high priority area in computer science is scientific visualization, with the entire second day of the workshop devoted to it.

  20. An overview of statistical decomposition techniques applied to complex systems

    PubMed Central

    Tuncer, Yalcin; Tanik, Murat M.; Allison, David B.

    2009-01-01

    The current state of the art in applied decomposition techniques is summarized within a comparative uniform framework. These techniques are classified by the parametric or information theoretic approaches they adopt. An underlying structural model common to all parametric approaches is outlined. The nature and premises of a typical information theoretic approach are stressed. Some possible application patterns for an information theoretic approach are illustrated. Composition is distinguished from decomposition by pointing out that the former is not a simple reversal of the latter. From the standpoint of application to complex systems, a general evaluation is provided. PMID:19724659

  1. Automated SEM Modal Analysis Applied to the Diogenites

    NASA Technical Reports Server (NTRS)

    Bowman, L. E.; Spilde, M. N.; Papike, James J.

    1996-01-01

    Analysis of volume proportions of minerals, or modal analysis, is routinely accomplished by point counting on an optical microscope, but the process, particularly on brecciated samples such as the diogenite meteorites, is tedious and prone to error by misidentification of very small fragments, which may make up a significant volume of the sample. Precise volume percentage data can be gathered on a scanning electron microscope (SEM) utilizing digital imaging and an energy dispersive spectrometer (EDS). This form of automated phase analysis reduces error, and at the same time provides more information than could be gathered using simple point counting alone, such as particle morphology statistics and chemical analyses. We have previously studied major, minor, and trace-element chemistry of orthopyroxene from a suite of diogenites. This abstract describes the method applied to determine the modes on this same suite of meteorites and the results of that research. The modal abundances thus determined add additional information on the petrogenesis of the diogenites. In addition, low-abundance phases such as spinels were located for further analysis by this method.

  2. Systems engineering and analysis

    SciTech Connect

    Blanchard, B.S.; Fabrycky, W.J.

    1981-01-01

    An introduction to systems is provided and tools for systems analysis are considered, taking into account system definitions and concepts, approaches for bringing systems into being, models in systems analysis, economic analysis techniques, mathematical modeling and optimization, probability and statistics, queuing theory and analysis, and control concepts and techniques. The system design process is discussed along with the design for operational feasibility, systems engineering management, and system design case studies. Attention is given to conceptual design, preliminary system design, detail design and development, system test and evaluation, design for reliability, design for maintainability, design for supportability, design for economic feasibility, communication system design, finite population system design, energy storage system design, and procurement-inventory system design.

  3. Research of the grid computing system applied in optical simulation

    NASA Astrophysics Data System (ADS)

    Jin, Wei-wei; Wang, Yu-dong; Liu, Qiangsheng; Cen, Zhao-feng; Li, Xiao-tong; Lin, Yi-qun

    2008-03-01

    A grid computing in the field of optics is presented in this paper. Firstly, the basic principles and research background of grid computing are outlined in this paper, along with the overview of its applications and the development status quo. The paper also discusses several typical tasks scheduling algorithms. Secondly, it focuses on describing a task scheduling of grid computing applied in optical computation. The paper gives details about the task scheduling system, including the task partition, granularity selection and tasks allocation, especially the structure of the system. In addition, some details of communication on grid computing are also illustrated. In this system, the "makespan" and "load balancing" are comprehensively considered. Finally, we build a grid model to test the task scheduling strategy, and the results are analyzed in detail. Compared to one isolated computer, a grid comprised of one server and four processors can shorten the "makespan" to 1/4. At the same time, the experimental results of the simulation also illustrate that the proposed scheduling system is able to balance loads of all processors. In short, the system performs scheduling well in the grid environment.

  4. An improved AVC strategy applied in distributed wind power system

    NASA Astrophysics Data System (ADS)

    Zhao, Y. N.; Liu, Q. H.; Song, S. Y.; Mao, W.

    2016-08-01

    Traditional AVC strategy is mainly used in wind farm and only concerns about grid connection point, which is not suitable for distributed wind power system. Therefore, this paper comes up with an improved AVC strategy applied in distributed wind power system. The strategy takes all nodes of distribution network into consideration and chooses the node having the most serious voltage deviation as control point to calculate the reactive power reference. In addition, distribution principles can be divided into two conditions: when wind generators access to network on single node, the reactive power reference is distributed according to reactive power capacity; when wind generators access to network on multi-node, the reference is distributed according to sensitivity. Simulation results show the correctness and reliability of the strategy. Compared with traditional control strategy, the strategy described in this paper can make full use of generators reactive power output ability according to the distribution network voltage condition and improve the distribution network voltage level effectively.

  5. Resonant-state expansion applied to planar open optical systems

    NASA Astrophysics Data System (ADS)

    Doost, M. B.; Langbein, W.; Muljarov, E. A.

    2012-02-01

    The resonant-state expansion (RSE), a rigorous perturbation theory of the Brillouin-Wigner type recently developed in electrodynamics[E. A. Muljarov, W. Langbein, and R. Zimmermann, Europhys. Lett.EULEEJ0295-507510.1209/0295-5075/92/50010 92, 50010 (2010)], is applied to planar, effectively one-dimensional optical systems, such as layered dielectric slabs and Bragg reflector microcavities. It is demonstrated that the RSE converges with a power law in the basis size. Algorithms for error estimation and their reduction by extrapolation are presented and evaluated. Complex eigenfrequencies, electromagnetic fields, and the Green's function of a selection of optical systems are calculated, as well as the observable transmission spectra. In particular, we find that for a Bragg-mirror microcavity, which has sharp resonances in the spectrum, the transmission calculated using the RSE reproduces the result of the transfer- or scattering-matrix method.

  6. Systems Vaccinology Applied to DNA Vaccines: Perspective and Challenges.

    PubMed

    Lever, Melissa; Silveira, Eduardo L; Nakaya, Helder I

    2017-01-01

    DNA vaccination represents a new milestone in our technological efforts to avoid infectious diseases. Although this method of vaccination has had success in providing protection in animals, these vaccines suffer from low immunogenicity in humans. Questions remain over the molecular mechanism of DNA vaccination, the best ways in which to safely increase vaccine reactogenecity, and what biomarkers can be used as correlates of protection. Systems vaccinology, which utilizes modern experimental and computational approaches to provide an integrated view of the vaccination process, offers the potential to answer these questions. In this review we discuss the current tools utilized in systems vaccinology, the ways in which they have and can be applied to DNA vaccinology, and challenges faced in the field.

  7. Applied Behavior Analysis is a Science and, Therefore, Progressive.

    PubMed

    Leaf, Justin B; Leaf, Ronald; McEachin, John; Taubman, Mitchell; Ala'i-Rosales, Shahla; Ross, Robert K; Smith, Tristram; Weiss, Mary Jane

    2016-02-01

    Applied behavior analysis (ABA) is a science and, therefore, involves progressive approaches and outcomes. In this commentary we argue that the spirit and the method of science should be maintained in order to avoid reductionist procedures, stifled innovation, and rote, unresponsive protocols that become increasingly removed from meaningful progress for individuals diagnosed with autism spectrum disorder (ASD). We describe this approach as progressive. In a progressive approach to ABA, the therapist employs a structured yet flexible process, which is contingent upon and responsive to child progress. We will describe progressive ABA, contrast it to reductionist ABA, and provide rationales for both the substance and intent of ABA as a progressive scientific method for improving conditions of social relevance for individuals with ASD.

  8. Evaluating the effectiveness of teacher training in Applied Behaviour Analysis.

    PubMed

    Grey, Ian M; Honan, Rita; McClean, Brian; Daly, Michael

    2005-09-01

    Interventions for children with autism based upon Applied Behaviour Analysis (ABA) has been repeatedly shown to be related both to educational gains and to reductions in challenging behaviours. However, to date, comprehensive training in ABA for teachers and others have been limited. Over 7 months, 11 teachers undertook 90 hours of classroom instruction and supervision in ABA. Each teacher conducted a comprehensive functional assessment and designed a behaviour support plan targeting one behaviour for one child with an autistic disorder. Target behaviours included aggression, non-compliance and specific educational skills. Teachers recorded observational data for the target behaviour for both baseline and intervention sessions. Support plans produced an average 80 percent change in frequency of occurrence of target behaviours. Questionnaires completed by parents and teachers at the end of the course indicated a beneficial effect for the children and the educational environment. The potential benefits of teacher implemented behavioural intervention are discussed.

  9. Statistical model applied to motor evoked potentials analysis.

    PubMed

    Ma, Ying; Thakor, Nitish V; Jia, Xiaofeng

    2011-01-01

    Motor evoked potentials (MEPs) convey information regarding the functional integrity of the descending motor pathways. Absence of the MEP has been used as a neurophysiological marker to suggest cortico-spinal abnormalities in the operating room. Due to their high variability and sensitivity, detailed quantitative studies of MEPs are lacking. This paper applies a statistical method to characterize MEPs by estimating the number of motor units and single motor unit potential amplitudes. A clearly increasing trend of single motor unit potential amplitudes in the MEPs after each pulse of the stimulation pulse train is revealed by this method. This statistical method eliminates the effects of anesthesia, and provides an objective assessment of MEPs. Consequently this statistical method has high potential to be useful in future quantitative MEPs analysis.

  10. Synchronisation and coupling analysis: applied cardiovascular physics in sleep medicine.

    PubMed

    Wessel, Niels; Riedl, Maik; Kramer, Jan; Muller, Andreas; Penzel, Thomas; Kurths, Jurgen

    2013-01-01

    Sleep is a physiological process with an internal program of a number of well defined sleep stages and intermediate wakefulness periods. The sleep stages modulate the autonomous nervous system and thereby the sleep stages are accompanied by different regulation regimes for the cardiovascular and respiratory system. The differences in regulation can be distinguished by new techniques of cardiovascular physics. The number of patients suffering from sleep disorders increases unproportionally with the increase of the human population and aging, leading to very high expenses in the public health system. Therefore, the challenge of cardiovascular physics is to develop highly-sophisticated methods which are able to, on the one hand, supplement and replace expensive medical devices and, on the other hand, improve the medical diagnostics with decreasing the patient's risk. Methods of cardiovascular physics are used to analyze heart rate, blood pressure and respiration to detect changes of the autonomous nervous system in different diseases. Data driven modeling analysis, synchronization and coupling analysis and their applications to biosignals in healthy subjects and patients with different sleep disorders are presented. Newly derived methods of cardiovascular physics can help to find indicators for these health risks.

  11. Robust regression applied to fractal/multifractal analysis.

    NASA Astrophysics Data System (ADS)

    Portilla, F.; Valencia, J. L.; Tarquis, A. M.; Saa-Requejo, A.

    2012-04-01

    Fractal and multifractal are concepts that have grown increasingly popular in recent years in the soil analysis, along with the development of fractal models. One of the common steps is to calculate the slope of a linear fit commonly using least squares method. This shouldn't be a special problem, however, in many situations using experimental data the researcher has to select the range of scales at which is going to work neglecting the rest of points to achieve the best linearity that in this type of analysis is necessary. Robust regression is a form of regression analysis designed to circumvent some limitations of traditional parametric and non-parametric methods. In this method we don't have to assume that the outlier point is simply an extreme observation drawn from the tail of a normal distribution not compromising the validity of the regression results. In this work we have evaluated the capacity of robust regression to select the points in the experimental data used trying to avoid subjective choices. Based on this analysis we have developed a new work methodology that implies two basic steps: • Evaluation of the improvement of linear fitting when consecutive points are eliminated based on R p-value. In this way we consider the implications of reducing the number of points. • Evaluation of the significance of slope difference between fitting with the two extremes points and fitted with the available points. We compare the results applying this methodology and the common used least squares one. The data selected for these comparisons are coming from experimental soil roughness transect and simulated based on middle point displacement method adding tendencies and noise. The results are discussed indicating the advantages and disadvantages of each methodology. Acknowledgements Funding provided by CEIGRAM (Research Centre for the Management of Agricultural and Environmental Risks) and by Spanish Ministerio de Ciencia e Innovación (MICINN) through project no

  12. Common cause evaluations in applied risk analysis of nuclear power plants. [PWR

    SciTech Connect

    Taniguchi, T.; Ligon, D.; Stamatelatos, M.

    1983-04-01

    Qualitative and quantitative approaches were developed for the evaluation of common cause failures (CCFs) in nuclear power plants and were applied to the analysis of the auxiliary feedwater systems of several pressurized water reactors (PWRs). Key CCF variables were identified through a survey of experts in the field and a review of failure experience in operating PWRs. These variables were classified into categories of high, medium, and low defense against a CCF. Based on the results, a checklist was developed for analyzing CCFs of systems. Several known techniques for quantifying CCFs were also reviewed. The information provided valuable insights in the development of a new model for estimating CCF probabilities, which is an extension of and improvement over the Beta Factor method. As applied to the analysis of the PWR auxiliary feedwater systems, the method yielded much more realistic values than the original Beta Factor method for a one-out-of-three system.

  13. Performance analysis of high quality parallel preconditioners applied to 3D finite element structural analysis

    SciTech Connect

    Kolotilina, L.; Nikishin, A.; Yeremin, A.

    1994-12-31

    The solution of large systems of linear equations is a crucial bottleneck when performing 3D finite element analysis of structures. Also, in many cases the reliability and robustness of iterative solution strategies, and their efficiency when exploiting hardware resources, fully determine the scope of industrial applications which can be solved on a particular computer platform. This is especially true for modern vector/parallel supercomputers with large vector length and for modern massively parallel supercomputers. Preconditioned iterative methods have been successfully applied to industrial class finite element analysis of structures. The construction and application of high quality preconditioners constitutes a high percentage of the total solution time. Parallel implementation of high quality preconditioners on such architectures is a formidable challenge. Two common types of existing preconditioners are the implicit preconditioners and the explicit preconditioners. The implicit preconditioners (e.g. incomplete factorizations of several types) are generally high quality but require solution of lower and upper triangular systems of equations per iteration which are difficult to parallelize without deteriorating the convergence rate. The explicit type of preconditionings (e.g. polynomial preconditioners or Jacobi-like preconditioners) require sparse matrix-vector multiplications and can be parallelized but their preconditioning qualities are less than desirable. The authors present results of numerical experiments with Factorized Sparse Approximate Inverses (FSAI) for symmetric positive definite linear systems. These are high quality preconditioners that possess a large resource of parallelism by construction without increasing the serial complexity.

  14. Applying Association Rule of the Data Mining Method for the Network Event Analysis

    NASA Astrophysics Data System (ADS)

    Kim, Wankyung; Soh, Wooyoung

    2007-12-01

    Network event analysis gives useful information on the network status that helps protect from attacks. It involves finding sets of frequently used packet information such as IP addresses and requires real-time processing by its nature. This paper applies association rules to network event analysis. Originally association rules used for data mining can be applied to find frequent item sets. So, if frequent items occur on networks, information system can guess that there is a threat. But existed association rules such as Apriori algorithm are not suitable for analyzing network events on real-time due to the high usage of CPU and memory and thus low processing speed. This paper develops a network event audit module by applying association rules to network events using a new algorithm instead of Apriori algorithm. Test results show that the application of the new algorithm gives drastically low usage of both CPU and memory for network event analysis compared with existing Apriori algorithm.

  15. Applying of digital signal processing to optical equisignal zone system

    NASA Astrophysics Data System (ADS)

    Maraev, Anton A.; Timofeev, Aleksandr N.; Gusarov, Vadim F.

    2015-05-01

    In this work we are trying to assess the application of array detectors and digital information processing to the system with the optical equisignal zone as a new method of evaluating of optical equisignal zone position. Peculiarities of optical equisignal zone formation are described. The algorithm of evaluation of optical equisignal zone position is applied to processing on the array detector. This algorithm enables to evaluate as lateral displacement as turning angles of the receiver relative to the projector. Interrelation of parameters of the projector and the receiver is considered. According to described principles an experimental set was made and then characterized. The accuracy of position evaluation of the equisignal zone is shown dependent of the size of the equivalent entrance pupil at processing.

  16. A Hygrothermal Risk Analysis Applied to Residential Unvented Attics

    SciTech Connect

    Pallin, Simon B; Kehrer, Manfred

    2013-01-01

    Aresidential building, constructed with an unvented attic, is acommonroof assembly in the United States.The expected hygrothermal performance and service life of the roof are difficult to estimate due to a number of varying parameters.Typical parameters expected to vary are the climate, direction, and slope of the roof as well as the radiation properties of the surface material. Furthermore, influential parameters are indoor moisture excess, air leakages through the attic floor, and leakages from air-handling unit and ventilation ducts. In addition, the type of building materials such as the insulation material and closed or open cell spray polyurethane foam will influence the future performance of the roof. A development of a simulation model of the roof assembly will enable a risk and sensitivity analysis, in which the most important varying parameters on the hygrothermal performance can be determined. The model is designed to perform probabilistic simulations using mathematical and hygrothermal calculation tools. The varying input parameters can be chosen from existing measurements, simulations, or standards. An analysis is applied to determine the risk of consequences, such as mold growth, rot, or energy demand of the HVAC unit. Furthermore, the future performance of the roof can be simulated in different climates to facilitate the design of an efficient and reliable roof construction with the most suitable technical solution and to determine the most appropriate building materials for a given climate

  17. Multitaper Spectral Analysis and Wavelet Denoising Applied to Helioseismic Data

    NASA Technical Reports Server (NTRS)

    Komm, R. W.; Gu, Y.; Hill, F.; Stark, P. B.; Fodor, I. K.

    1999-01-01

    Estimates of solar normal mode frequencies from helioseismic observations can be improved by using Multitaper Spectral Analysis (MTSA) to estimate spectra from the time series, then using wavelet denoising of the log spectra. MTSA leads to a power spectrum estimate with reduced variance and better leakage properties than the conventional periodogram. Under the assumption of stationarity and mild regularity conditions, the log multitaper spectrum has a statistical distribution that is approximately Gaussian, so wavelet denoising is asymptotically an optimal method to reduce the noise in the estimated spectra. We find that a single m-upsilon spectrum benefits greatly from MTSA followed by wavelet denoising, and that wavelet denoising by itself can be used to improve m-averaged spectra. We compare estimates using two different 5-taper estimates (Stepian and sine tapers) and the periodogram estimate, for GONG time series at selected angular degrees l. We compare those three spectra with and without wavelet-denoising, both visually, and in terms of the mode parameters estimated from the pre-processed spectra using the GONG peak-fitting algorithm. The two multitaper estimates give equivalent results. The number of modes fitted well by the GONG algorithm is 20% to 60% larger (depending on l and the temporal frequency) when applied to the multitaper estimates than when applied to the periodogram. The estimated mode parameters (frequency, amplitude and width) are comparable for the three power spectrum estimates, except for modes with very small mode widths (a few frequency bins), where the multitaper spectra broadened the modest compared with the periodogram. We tested the influence of the number of tapers used and found that narrow modes at low n values are broadened to the extent that they can no longer be fit if the number of tapers is too large. For helioseismic time series of this length and temporal resolution, the optimal number of tapers is less than 10.

  18. The Evidence-Based Practice of Applied Behavior Analysis.

    PubMed

    Slocum, Timothy A; Detrich, Ronnie; Wilczynski, Susan M; Spencer, Trina D; Lewis, Teri; Wolfe, Katie

    2014-05-01

    Evidence-based practice (EBP) is a model of professional decision-making in which practitioners integrate the best available evidence with client values/context and clinical expertise in order to provide services for their clients. This framework provides behavior analysts with a structure for pervasive use of the best available evidence in the complex settings in which they work. This structure recognizes the need for clear and explicit understanding of the strength of evidence supporting intervention options, the important contextual factors including client values that contribute to decision making, and the key role of clinical expertise in the conceptualization, intervention, and evaluation of cases. Opening the discussion of EBP in this journal, Smith (The Behavior Analyst, 36, 7-33, 2013) raised several key issues related to EBP and applied behavior analysis (ABA). The purpose of this paper is to respond to Smith's arguments and extend the discussion of the relevant issues. Although we support many of Smith's (The Behavior Analyst, 36, 7-33, 2013) points, we contend that Smith's definition of EBP is significantly narrower than definitions that are used in professions with long histories of EBP and that this narrowness conflicts with the principles that drive applied behavior analytic practice. We offer a definition and framework for EBP that aligns with the foundations of ABA and is consistent with well-established definitions of EBP in medicine, psychology, and other professions. In addition to supporting the systematic use of research evidence in behavior analytic decision making, this definition can promote clear communication about treatment decisions across disciplines and with important outside institutions such as insurance companies and granting agencies.

  19. Advanced imaging systems for diagnostic investigations applied to Cultural Heritage

    NASA Astrophysics Data System (ADS)

    Peccenini, E.; Albertin, F.; Bettuzzi, M.; Brancaccio, R.; Casali, F.; Morigi, M. P.; Petrucci, F.

    2014-12-01

    The diagnostic investigations are an important resource in the studies on Cultural Heritage to enhance the knowledge on execution techniques, materials and conservation status of a work of art. In this field, due to the great historical and artistic value of the objects, preservation is the main concern; for this reason, new technological equipment has been designed and developed in the Physics Departments of the Universities of Ferrara and Bologna to enhance the non-invasive approach to the study of pictorial artworks and other objects of cultural interest. Infrared (IR) reflectography, X-ray radiography and computed tomography (CT), applied to works of art, are joined by the same goal: to get hidden information on execution techniques and inner structure pursuing the non-invasiveness of the methods, although using different setup and physical principles. In this work transportable imaging systems to investigate large objects in museums and galleries are presented. In particular, 2D scanning devices for IR reflectography and X-ray radiography, CT systems and some applications to the Cultural Heritage are described.

  20. Analysis of possibility of applying the PVDF foil in industrial vibration sensors

    NASA Astrophysics Data System (ADS)

    Wróbel, A.

    2015-11-01

    There are many machines using the piezoelectric effects. Systems with smart materials are often used because they have high potential applications for example transducers can be applied to receive required characteristic of projected system. Every engineer and designer know how important it is properly mathematical model and method of the analysis. Also it is important to consider all parameters of analyzed system for example glue layer between elements. Geometrical and material parameters has a significant impact on the characteristics of the all system's components because the omission of the influence of one of them results in inaccuracy in the analysis of the system. In article the modeling and testing of vibrating systems with piezoelectric ceramic materials transducers used as actuators and vibration dampers. The method of analysis of the vibrating sensor systems will be presented, mathematical model, and characteristics, to determine the influence of the system's properties on these characteristics. Main scientific point of the project is to analyze and demonstrate possibility of applying new construction with the PVDF foil or any other belonging to a group of smart materials in industrial sensors. Currently, the vibration level sensors are used by practically all manufacturers of piezoelectric ceramic plates to generate and detect the vibration of the fork.

  1. To apply or not to apply: a survey analysis of grant writing costs and benefits.

    PubMed

    von Hippel, Ted; von Hippel, Courtney

    2015-01-01

    We surveyed 113 astronomers and 82 psychologists active in applying for federally funded research on their grant-writing history between January, 2009 and November, 2012. We collected demographic data, effort levels, success rates, and perceived non-financial benefits from writing grant proposals. We find that the average proposal takes 116 PI hours and 55 CI hours to write; although time spent writing was not related to whether the grant was funded. Effort did translate into success, however, as academics who wrote more grants received more funding. Participants indicated modest non-monetary benefits from grant writing, with psychologists reporting a somewhat greater benefit overall than astronomers. These perceptions of non-financial benefits were unrelated to how many grants investigators applied for, the number of grants they received, or the amount of time they devoted to writing their proposals. We also explored the number of years an investigator can afford to apply unsuccessfully for research grants and our analyses suggest that funding rates below approximately 20%, commensurate with current NIH and NSF funding, are likely to drive at least half of the active researchers away from federally funded research. We conclude with recommendations and suggestions for individual investigators and for department heads.

  2. To Apply or Not to Apply: A Survey Analysis of Grant Writing Costs and Benefits

    PubMed Central

    von Hippel, Ted; von Hippel, Courtney

    2015-01-01

    We surveyed 113 astronomers and 82 psychologists active in applying for federally funded research on their grant-writing history between January, 2009 and November, 2012. We collected demographic data, effort levels, success rates, and perceived non-financial benefits from writing grant proposals. We find that the average proposal takes 116 PI hours and 55 CI hours to write; although time spent writing was not related to whether the grant was funded. Effort did translate into success, however, as academics who wrote more grants received more funding. Participants indicated modest non-monetary benefits from grant writing, with psychologists reporting a somewhat greater benefit overall than astronomers. These perceptions of non-financial benefits were unrelated to how many grants investigators applied for, the number of grants they received, or the amount of time they devoted to writing their proposals. We also explored the number of years an investigator can afford to apply unsuccessfully for research grants and our analyses suggest that funding rates below approximately 20%, commensurate with current NIH and NSF funding, are likely to drive at least half of the active researchers away from federally funded research. We conclude with recommendations and suggestions for individual investigators and for department heads. PMID:25738742

  3. Applying Lean: Implementation of a Rapid Triage and Treatment System

    PubMed Central

    Murrell, Karen L.; Offerman, Steven R.; Kauffman, Mark B.

    2011-01-01

    Objective: Emergency department (ED) crowding creates issues with patient satisfaction, long wait times and leaving the ED without being seen by a doctor (LWBS). Our objective was to evaluate how applying Lean principles to develop a Rapid Triage and Treatment (RTT) system affected ED metrics in our community hospital. Methods: Using Lean principles, we made ED process improvements that led to the RTT system. Using this system, patients undergo a rapid triage with low-acuity patients seen and treated by a physician in the triage area. No changes in staffing, physical space or hospital resources occurred during the study period. We then performed a retrospective, observational study comparing hospital electronic medical record data six months before and six months after implementation of the RTT system. Results: ED census was 30,981 in the six months prior to RTT and 33,926 after. Ambulance arrivals, ED patient acuity and hospital admission rates were unchanged throughout the study periods. Mean ED length of stay was longer in the period before RTT (4.2 hours, 95% confidence interval [CI] = 4.2–4.3; standard deviation [SD] = 3.9) than after (3.6 hours, 95% CI = 3.6–3.7; SD = 3.7). Mean ED arrival to physician start time was 62.2 minutes (95% CI = 61.5–63.0; SD = 58.9) prior to RTT and 41.9 minutes (95% CI = 41.5–42.4; SD = 30.9) after. The LWBS rate for the six months prior to RTT was 4.5% (95% CI = 3.1–5.5) and 1.5% (95% CI = 0.6–1.8) after RTT initiation. Conclusion: Our experience shows that changes in ED processes using Lean thinking and available resources can improve efficiency. In this community hospital ED, use of an RTT system decreased patient wait times and LWBS rates. PMID:21691524

  4. Applying DNA computation to intractable problems in social network analysis.

    PubMed

    Chen, Rick C S; Yang, Stephen J H

    2010-09-01

    From ancient times to the present day, social networks have played an important role in the formation of various organizations for a range of social behaviors. As such, social networks inherently describe the complicated relationships between elements around the world. Based on mathematical graph theory, social network analysis (SNA) has been developed in and applied to various fields such as Web 2.0 for Web applications and product developments in industries, etc. However, some definitions of SNA, such as finding a clique, N-clique, N-clan, N-club and K-plex, are NP-complete problems, which are not easily solved via traditional computer architecture. These challenges have restricted the uses of SNA. This paper provides DNA-computing-based approaches with inherently high information density and massive parallelism. Using these approaches, we aim to solve the three primary problems of social networks: N-clique, N-clan, and N-club. Their accuracy and feasible time complexities discussed in the paper will demonstrate that DNA computing can be used to facilitate the development of SNA.

  5. Applying microscopy to the analysis of nuclear structure and function.

    PubMed

    Iborra, Francisco; Cook, Peter R; Jackson, Dean A

    2003-02-01

    One of the ultimate goals of biological research is to understand mechanisms of cell function within living organisms. With this in mind, many sophisticated technologies that allow us to inspect macromolecular structure in exquisite detail have been developed. Although knowledge of structure derived from techniques such as X-ray crystallography and nuclear magnetic resonance is of vital importance, these approaches cannot reveal the remarkable complexity of molecular interactions that exists in vivo. With this in mind, this review focuses on the use of microscopy techniques to analyze cell structure and function. We describe the different basic microscopic methodologies and how the routine techniques are best applied to particular biological problems. We also emphasize the specific capabilities and uses of light and electron microscopy and highlight their individual advantages and disadvantages. For completion, we also comment on the alternative possibilities provided by a variety of advanced imaging technologies. We hope that this brief analysis of the undoubted power of microscopy techniques will be enough to stimulate a wider participation in this rapidly developing area of biological discovery.

  6. Gastritis staging: interobserver agreement by applying OLGA and OLGIM systems.

    PubMed

    Isajevs, Sergejs; Liepniece-Karele, Inta; Janciauskas, Dainius; Moisejevs, Georgijs; Putnins, Viesturs; Funka, Konrads; Kikuste, Ilze; Vanags, Aigars; Tolmanis, Ivars; Leja, Marcis

    2014-04-01

    Atrophic gastritis remains a difficult histopathological diagnosis with low interobserver agreement. The aim of our study was to compare gastritis staging and interobserver agreement between general and expert gastrointestinal (GI) pathologists using Operative Link for Gastritis Assessment (OLGA) and Operative Link on Gastric Intestinal Metaplasia (OLGIM). We enrolled 835 patients undergoing upper endoscopy in the study. Two general and two expert gastrointestinal pathologists graded biopsy specimens according to the Sydney classification, and the stage of gastritis was assessed by OLGA and OLGIM system. Using OLGA, 280 (33.4 %) patients had gastritis (stage I-IV), whereas with OLGIM this was 167 (19.9 %). OLGA stage III- IV gastritis was observed in 25 patients, whereas by OLGIM stage III-IV was found in 23 patients. Interobserver agreement between expert GI pathologists for atrophy in the antrum, incisura angularis, and corpus was moderate (kappa = 0.53, 0.57 and 0.41, respectively, p < 0.0001), but almost perfect for intestinal metaplasia (kappa = 0.82, 0.80 and 0.81, respectively, p < 0.0001). However, interobserver agreement between general pathologists was poor for atrophy, but moderate for intestinal metaplasia. OLGIM staging provided the highest interobserver agreement, but a substantial proportion of potentially high-risk individuals would be missed if only OLGIM staging is applied. Therefore, we recommend to use a combination of OLGA and OLGIM for staging of chronic gastritis.

  7. Toward a Blended Ontology: Applying Knowledge Systems to ...

    EPA Pesticide Factsheets

    Bionanomedicine and environmental research share need common terms and ontologies. This study applied knowledge systems, data mining, and bibliometrics used in nano-scale ADME research from 1991 to 2011. The prominence of nano-ADME in environmental research began to exceed the publication rate in medical research in 2006. That trend appears to continue as a result of the growing products in commerce using nanotechnology, that is, 5-fold growth in number of countries with nanomaterials research centers. Funding for this research virtually did not exist prior to 2002, whereas today both medical and environmental research is funded globally. Key nanoparticle research began with pharmacology and therapeutic drug-delivery and contrasting agents, but the advances have found utility in the environmental research community. As evidence ultrafine aerosols and aquatic colloids research increased 6-fold, indicating a new emphasis on environmental nanotoxicology. User-directed expert elicitation from the engineering and chemical/ADME domains can be combined with appropriate Boolean logic and queries to define the corpus of nanoparticle interest. The study combined pharmacological expertise and informatics to identify the corpus by building logical conclusions and observations. Publication records informatics can lead to an enhanced understanding the connectivity between fields, as well as overcoming the differences in ontology between the fields. The National Exposure Resea

  8. The Significant Structure Theory Applied to a Mesophase System

    PubMed Central

    Ma, Shao-mu; Eyring, H.

    1975-01-01

    The significant structure theory of liquids is extended to the mesophase system with p-azoxyanisole as an example. This compound has two different structures, a nematic phase and an isotropic phase, in its liquid state. In this study the nematic phase is treated as subject to a second volume and temperature-dependent degeneracy formally like that due to melting. The isotropic phase is treated as a normal liquid. The specific heat, thermal expansion coefficient, compressibility, volume, entropy of transitions, and heat of transitions are calculated and compared to the observed values. This analysis differs from previous ones in including the volume dependence as well as the temperature dependence in one explicit expression for the Helmholtz free energy. PMID:16592217

  9. LIBRARY SYSTEMS ANALYSIS.

    ERIC Educational Resources Information Center

    HIEBER, CAROLINE E.; TAYLOR, ROBERT S.

    STEPS THAT THE LIBRARY CAN TAKE IN PREPARING FOR A CHANGE TO AN AUTOMATED SYSTEM WERE INVESTIGATED. THE METHOD DESCRIBED WAS BASED ON AN ANALYSIS OF CLERICAL AND OFFICE WORK CALLED INTEGRATED PROCEDURES OF CONTROL (IPC). THE APPLICATION OF LIBRARY SYSTEMS ANALYSIS (LISA) TO THE LEHIGH UNIVERSITY LIBRARY IS DESCRIBED. THIS PROCESS INVOLVED (1)…

  10. BATSE spectroscopy analysis system

    NASA Technical Reports Server (NTRS)

    Schaefer, Bradley E.; Bansal, Sandhia; Basu, Anju; Brisco, Phil; Cline, Thomas L.; Friend, Elliott; Laubenthal, Nancy; Panduranga, E. S.; Parkar, Nuru; Rust, Brad

    1992-01-01

    The Burst and Transient Source Experiment (BATSE) Spectroscopy Analysis System (BSAS) is the software system which is the primary tool for the analysis of spectral data from BATSE. As such, Guest Investigators and the community as a whole need to know its basic properties and characteristics. Described here are the characteristics of the BATSE spectroscopy detectors and the BSAS.

  11. Operational modal analysis applied to the concert harp

    NASA Astrophysics Data System (ADS)

    Chomette, B.; Le Carrou, J.-L.

    2015-05-01

    Operational modal analysis (OMA) methods are useful to extract modal parameters of operating systems. These methods seem to be particularly interesting to investigate the modal basis of string instruments during operation to avoid certain disadvantages due to conventional methods. However, the excitation in the case of string instruments is not optimal for OMA due to the presence of damped harmonic components and low noise in the disturbance signal. Therefore, the present study investigates the least-square complex exponential (LSCE) and the modified least-square complex exponential methods in the case of a string instrument to identify modal parameters of the instrument when it is played. The efficiency of the approach is experimentally demonstrated on a concert harp excited by some of its strings and the two methods are compared to a conventional modal analysis. The results show that OMA allows us to identify modes particularly present in the instrument's response with a good estimation especially if they are close to the excitation frequency with the modified LSCE method.

  12. Principles of micellar electrokinetic capillary chromatography applied in pharmaceutical analysis.

    PubMed

    Hancu, Gabriel; Simon, Brigitta; Rusu, Aura; Mircia, Eleonora; Gyéresi, Arpád

    2013-01-01

    Since its introduction capillary electrophoresis has shown great potential in areas where electrophoretic techniques have rarely been used before, including here the analysis of pharmaceutical substances. The large majority of pharmaceutical substances are neutral from electrophoretic point of view, consequently separations by the classic capillary zone electrophoresis; where separation is based on the differences between the own electrophoretic mobilities of the analytes; are hard to achieve. Micellar electrokinetic capillary chromatography, a hybrid method that combines chromatographic and electrophoretic separation principles, extends the applicability of capillary electrophoretic methods to neutral analytes. In micellar electrokinetic capillary chromatography, surfactants are added to the buffer solution in concentration above their critical micellar concentrations, consequently micelles are formed; micelles that undergo electrophoretic migration like any other charged particle. The separation is based on the differential partitioning of an analyte between the two-phase system: the mobile aqueous phase and micellar pseudostationary phase. The present paper aims to summarize the basic aspects regarding separation principles and practical applications of micellar electrokinetic capillary chromatography, with particular attention to those relevant in pharmaceutical analysis.

  13. Differential Network Analysis Applied to Preoperative Breast Cancer Chemotherapy Response

    PubMed Central

    Warsow, Gregor; Struckmann, Stephan; Kerkhoff, Claus; Reimer, Toralf; Engel, Nadja; Fuellen, Georg

    2013-01-01

    In silico approaches are increasingly considered to improve breast cancer treatment. One of these treatments, neoadjuvant TFAC chemotherapy, is used in cases where application of preoperative systemic therapy is indicated. Estimating response to treatment allows or improves clinical decision-making and this, in turn, may be based on a good understanding of the underlying molecular mechanisms. Ever increasing amounts of high throughput data become available for integration into functional networks. In this study, we applied our software tool ExprEssence to identify specific mechanisms relevant for TFAC therapy response, from a gene/protein interaction network. We contrasted the resulting active subnetwork to the subnetworks of two other such methods, OptDis and KeyPathwayMiner. We could show that the ExprEssence subnetwork is more related to the mechanistic functional principles of TFAC therapy than the subnetworks of the other two methods despite the simplicity of ExprEssence. We were able to validate our method by recovering known mechanisms and as an application example of our method, we identified a mechanism that may further explain the synergism between paclitaxel and doxorubicin in TFAC treatment: Paclitaxel may attenuate MELK gene expression, resulting in lower levels of its target MYBL2, already associated with doxorubicin synergism in hepatocellular carcinoma cell lines. We tested our hypothesis in three breast cancer cell lines, confirming it in part. In particular, the predicted effect on MYBL2 could be validated, and a synergistic effect of paclitaxel and doxorubicin could be demonstrated in the breast cancer cell lines SKBR3 and MCF-7. PMID:24349128

  14. Factor Analysis Applied the VFY-218 RCS Data

    NASA Technical Reports Server (NTRS)

    Woo, Alex; Chancellor, Marisa K. (Technical Monitor)

    1997-01-01

    Present statistical factor analysis of computer simulations and measurement data for the VFY-218 configuration. Factor analysis try to quantify the statistical grouping of measurements and simulations.

  15. Fundamental and applied studies of organic photovoltaic systems

    NASA Astrophysics Data System (ADS)

    Hill, Caleb M.

    Presented here are applied and fundamental studies of model organic photovoltaic (OPV) systems. Graphene oxide (GO) nanosheets were investigated as a potential electron acceptor in bulk heterojunction organic solar cells which employed poly[3-hexylthiophene] (P3HT) as an electron donor. GO nanosheets were transferred into organic solution through a surfactant-assisted phase transfer method. Electron transfer from P3HT to GO in solutions and thin films was established through fluorescence spectroscopy. Bulk heterojunction solar cells containing P3HT, P3HT-GO, and P3HT-phenyl-C61-butyric acid methyl ester (PCBM, a prototypical elector acceptor employed in polymer solar cells) were constructed and evaluated. Single molecule fluorescence spectroscopy was employed to study charge transfer between conjugated polymers and TiO2 at the single molecule level. The fluorescence of individual chains of the conjugated polymer poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) at TiO2 surfaces was shown to exhibit increased intermittent (on/off "blinking") behavior compared to molecules on glass substrates. Single molecule fluorescence excitation anisotropy measurements showed the conformation of the polymer molecules did not differ appreciably between glass and TiO 2 substrates. The similarities in molecular conformation suggest that the observed differences in blinking activity are due to charge transfer between MEH-PPV and TiO2, which provides additional pathways between states of high and low fluorescence quantum efficiency. The electrodeposition of individual Ag nanoparticles (NPs), which can be used to enhance light harvesting in organic photovoltaic systems, was studied in situ via dark field scattering (DFS) microscopy. The scattering at the surface of an indium tin oxide (ITO) working electrode was measured during a potential sweep. Utilizing Mie scattering theory and high resolution scanning electron microscopy (SEM), the scattering data were used to

  16. Phase plane analysis: applying chaos theory in health care.

    PubMed

    Priesmeyer, H R; Sharp, L F

    1995-01-01

    This article applies the new science of nonlinearity to administrative issues and accounts receivable management in health care, and it provides a new perspective on common operating and quality control measures.

  17. Evaluation of atrazine degradation applied to different energy systems.

    PubMed

    Moreira, Ailton J; Pinheiro, Bianca S; Araújo, André F; Freschi, Gian P G

    2016-09-01

    Atrazine is an herbicide widely used in crops and has drawn attention due to potential pollution present in soil, sediment, water, and food. Since conventional methods are not potentially efficient to persistent degradation of organic compounds, new technology has been developed to remove them, especially practices utilizing advanced oxidation processes (AOPs). This work aims to evaluate the use of different energies (ultraviolet (UV), microwaves (MW), and radiations (MW-UV)) to the herbicide atrazine through the process of photo-oxidation. These systems found degradation rates of around 12 % (UV), 28 % (MW), and 83 % (MW-UV), respectively, with time intervals of 120 s. After the photolytic processes, the samples were analyzed at a wavelength scanning the range of 190 to 300 nm, where the spectral analysis of the signal was used to evaluate the degradation of atrazine and the appearance of some other peaks (degradation products). The spectrum evaluation resulting from photolytic processes gave rise to a new signal which was confirmed by chromatography. This spectrum indicated the possible pathway of atrazine degradation by the process of photolytic MW-UV, generating atrazine-2-hydroxy, atrazine-desethyl-2-hidroxy, and atrazine-desisopropyl-2-hydroxy. The process indicated that in all situations, chloride was present in the analytic structure and was substituted by a hydroxyl group, which lowered the toxicity of the compound through the photolytic process MW-UV. Chromatographic analysis ascertained these preliminary assessments using spectrophotometry. It was also significantly observed that the process can be optimized by adjusting the pH of the solution, which was evident by an improvement of 10 % in the rate of degradation when subjected to a pH solution equal to 8.37.

  18. Information Management Principles Applied to the Ballistic Missile Defense System

    DTIC Science & Technology

    2007-03-01

    if they are being applied. iv Acknowledgments I would like to thank the members who participated in the Delphi Group. Their...52 Initial Delphi Results...55 Second Round Delphi Results .............................................................................57

  19. Multi-Criteria Analysis for Biomass Utilization Applying Data Envelopment Analysis

    NASA Astrophysics Data System (ADS)

    Morimoto, Hidetsugu; Hoshino, Satoshi; Kuki, Yasuaki

    This paper aimed to consider about material-recycling, preventing global warming, and economic efficiency on preset and planed 195 Biomass Towns applying DEA (Data Envelopment Analysis), which can evaluate operational efficiency entities such as private companies or projects. In the results, although the Biomass Town can recycle material efficiently, it was clarified that preventing global warming and business profitability was brushed off like it in Biomass Town Design. Moreover, from the point of view of operational efficiency, we suggested an improvement of the Biomass Town scale for more efficiency-enhancing applying DEA. We found that applying DEA was able to catch more improvements or indicator as compared with cost-benefit analysis and cost-effectiveness analysis.

  20. Space elevator systems level analysis

    SciTech Connect

    Laubscher, B. E.

    2004-01-01

    The Space Elevator (SE) represents a major paradigm shift in space access. It involves new, untried technologies in most of its subsystems. Thus the successful construction of the SE requires a significant amount of development, This in turn implies a high level of risk for the SE. This paper will present a systems level analysis of the SE by subdividing its components into their subsystems to determine their level of technological maturity. such a high-risk endeavor is to follow a disciplined approach to the challenges. A systems level analysis informs this process and is the guide to where resources should be applied in the development processes. It is an efficient path that, if followed, minimizes the overall risk of the system's development. systems level analysis is that the overall system is divided naturally into its subsystems, and those subsystems are further subdivided as appropriate for the analysis. By dealing with the complex system in layers, the parameter space of decisions is kept manageable. Moreover, A rational way to manage One key aspect of a resources are not expended capriciously; rather, resources are put toward the biggest challenges and most promising solutions. This overall graded approach is a proven road to success. The analysis includes topics such as nanotube technology, deployment scenario, power beaming technology, ground-based hardware and operations, ribbon maintenance and repair and climber technology.

  1. Multisensor Image Analysis System

    DTIC Science & Technology

    1993-04-15

    AD-A263 679 II Uli! 91 Multisensor Image Analysis System Final Report Authors. Dr. G. M. Flachs Dr. Michael Giles Dr. Jay Jordan Dr. Eric...or decision, unless so designated by other documentation. 93-09739 *>ft s n~. now illlllM3lMVf Multisensor Image Analysis System Final...Multisensor Image Analysis System 3. REPORT TYPE AND DATES COVERED FINAL: LQj&tt-Z JZOfVL 5. FUNDING NUMBERS 93 > 6. AUTHOR(S) Drs. Gerald

  2. SUBSURFACE VISUAL ALARM SYSTEM ANALYSIS

    SciTech Connect

    D.W. Markman

    2001-08-06

    The ''Subsurface Fire Hazard Analysis'' (CRWMS M&O 1998, page 61), and the document, ''Title III Evaluation Report for the Surface and Subsurface Communication System'', (CRWMS M&O 1999a, pages 21 and 23), both indicate the installed communication system is adequate to support Exploratory Studies Facility (ESF) activities with the exception of the mine phone system for emergency notification purposes. They recommend the installation of a visual alarm system to supplement the page/party phone system The purpose of this analysis is to identify data communication highway design approaches, and provide justification for the selected or recommended alternatives for the data communication of the subsurface visual alarm system. This analysis is being prepared to document a basis for the design selection of the data communication method. This analysis will briefly describe existing data or voice communication or monitoring systems within the ESF, and look at how these may be revised or adapted to support the needed data highway of the subsurface visual alarm. system. The existing PLC communication system installed in subsurface is providing data communication for alcove No.5 ventilation fans, south portal ventilation fans, bulkhead doors and generator monitoring system. It is given that the data communication of the subsurface visual alarm system will be a digital based system. It is also given that it is most feasible to take advantage of existing systems and equipment and not consider an entirely new data communication system design and installation. The scope and primary objectives of this analysis are to: (1) Briefly review and describe existing available data communication highways or systems within the ESF. (2) Examine technical characteristics of an existing system to disqualify a design alternative is paramount in minimizing the number of and depth of a system review. (3) Apply general engineering design practices or criteria such as relative cost, and degree of

  3. Classical linear-control analysis applied to business-cycle dynamics and stability

    NASA Technical Reports Server (NTRS)

    Wingrove, R. C.

    1983-01-01

    Linear control analysis is applied as an aid in understanding the fluctuations of business cycles in the past, and to examine monetary policies that might improve stabilization. The analysis shows how different policies change the frequency and damping of the economic system dynamics, and how they modify the amplitude of the fluctuations that are caused by random disturbances. Examples are used to show how policy feedbacks and policy lags can be incorporated, and how different monetary strategies for stabilization can be analytically compared. Representative numerical results are used to illustrate the main points.

  4. Systems Analysis Sub site

    SciTech Connect

    EERE

    2012-03-16

    Systems analysis provides direction, focus, and support for the development and introduction of hydrogen production, storage, and end-use technologies, and provides a basis for recommendations on a balanced portfolio of activities.

  5. Measurement uncertainty analysis techniques applied to PV performance measurements

    SciTech Connect

    Wells, C.

    1992-10-01

    The purpose of this presentation is to provide a brief introduction to measurement uncertainty analysis, outline how it is done, and illustrate uncertainty analysis with examples drawn from the PV field, with particular emphasis toward its use in PV performance measurements. The uncertainty information we know and state concerning a PV performance measurement or a module test result determines, to a significant extent, the value and quality of that result. What is measurement uncertainty analysis It is an outgrowth of what has commonly been called error analysis. But uncertainty analysis, a more recent development, gives greater insight into measurement processes and tests, experiments, or calibration results. Uncertainty analysis gives us an estimate of the I interval about a measured value or an experiment's final result within which we believe the true value of that quantity will lie. Why should we take the time to perform an uncertainty analysis A rigorous measurement uncertainty analysis: Increases the credibility and value of research results; allows comparisons of results from different labs; helps improve experiment design and identifies where changes are needed to achieve stated objectives (through use of the pre-test analysis); plays a significant role in validating measurements and experimental results, and in demonstrating (through the post-test analysis) that valid data have been acquired; reduces the risk of making erroneous decisions; demonstrates quality assurance and quality control measures have been accomplished; define Valid Data as data having known and documented paths of: Origin, including theory; measurements; traceability to measurement standards; computations; uncertainty analysis of results.

  6. Launch vehicle systems design analysis

    NASA Technical Reports Server (NTRS)

    Ryan, Robert; Verderaime, V.

    1993-01-01

    Current launch vehicle design emphasis is on low life-cycle cost. This paper applies total quality management (TQM) principles to a conventional systems design analysis process to provide low-cost, high-reliability designs. Suggested TQM techniques include Steward's systems information flow matrix method, quality leverage principle, quality through robustness and function deployment, Pareto's principle, Pugh's selection and enhancement criteria, and other design process procedures. TQM quality performance at least-cost can be realized through competent concurrent engineering teams and brilliance of their technical leadership.

  7. Applied Missing Data Analysis. Methodology in the Social Sciences Series

    ERIC Educational Resources Information Center

    Enders, Craig K.

    2010-01-01

    Walking readers step by step through complex concepts, this book translates missing data techniques into something that applied researchers and graduate students can understand and utilize in their own research. Enders explains the rationale and procedural details for maximum likelihood estimation, Bayesian estimation, multiple imputation, and…

  8. How Has Applied Behavior Analysis and Behavior Therapy Changed?: An Historical Analysis of Journals

    ERIC Educational Resources Information Center

    O'Donohue, William; Fryling, Mitch

    2007-01-01

    Applied behavior analysis and behavior therapy are now nearly a half century old. It is interesting to ask if and how these disciplines have changed over time, particularly regarding some of their key internal controversies (e.g., role of cognitions). We examined the first five years and the 2000-2004 five year period of the "Journal of Applied…

  9. Applying Model Analysis to a Resource-Based Analysis of the Force and Motion Conceptual Evaluation

    ERIC Educational Resources Information Center

    Smith, Trevor I.; Wittmann, Michael C.; Carter, Tom

    2014-01-01

    Previously, we analyzed the Force and Motion Conceptual Evaluation in terms of a resources-based model that allows for clustering of questions so as to provide useful information on how students correctly or incorrectly reason about physics. In this paper, we apply model analysis to show that the associated model plots provide more information…

  10. Quantitative Schlieren analysis applied to holograms of crystals grown on Spacelab 3

    NASA Technical Reports Server (NTRS)

    Brooks, Howard L.

    1986-01-01

    In order to extract additional information about crystals grown in the microgravity environment of Spacelab, a quantitative schlieren analysis technique was developed for use in a Holography Ground System of the Fluid Experiment System. Utilizing the Unidex position controller, it was possible to measure deviation angles produced by refractive index gradients of 0.5 milliradians. Additionally, refractive index gradient maps for any recorded time during the crystal growth were drawn and used to create solute concentration maps for the environment around the crystal. The technique was applied to flight holograms of Cell 204 of the Fluid Experiment System that were recorded during the Spacelab 3 mission on STS 51B. A triglycine sulfate crystal was grown under isothermal conditions in the cell and the data gathered with the quantitative schlieren analysis technique is consistent with a diffusion limited growth process.

  11. Measurement uncertainty analysis techniques applied to PV performance measurements

    SciTech Connect

    Wells, C

    1992-10-01

    The purpose of this presentation is to provide a brief introduction to measurement uncertainty analysis, outline how it is done, and illustrate uncertainty analysis with examples drawn from the PV field, with particular emphasis toward its use in PV performance measurements. The uncertainty information we know and state concerning a PV performance measurement or a module test result determines, to a significant extent, the value and quality of that result. What is measurement uncertainty analysis? It is an outgrowth of what has commonly been called error analysis. But uncertainty analysis, a more recent development, gives greater insight into measurement processes and tests, experiments, or calibration results. Uncertainty analysis gives us an estimate of the I interval about a measured value or an experiment`s final result within which we believe the true value of that quantity will lie. Why should we take the time to perform an uncertainty analysis? A rigorous measurement uncertainty analysis: Increases the credibility and value of research results; allows comparisons of results from different labs; helps improve experiment design and identifies where changes are needed to achieve stated objectives (through use of the pre-test analysis); plays a significant role in validating measurements and experimental results, and in demonstrating (through the post-test analysis) that valid data have been acquired; reduces the risk of making erroneous decisions; demonstrates quality assurance and quality control measures have been accomplished; define Valid Data as data having known and documented paths of: Origin, including theory; measurements; traceability to measurement standards; computations; uncertainty analysis of results.

  12. Space lab system analysis

    NASA Technical Reports Server (NTRS)

    Rives, T. B.; Ingels, F. M.

    1988-01-01

    An analysis of the Automated Booster Assembly Checkout System (ABACS) has been conducted. A computer simulation of the ETHERNET LAN has been written. The simulation allows one to investigate different structures of the ABACS system. The simulation code is in PASCAL and is VAX compatible.

  13. Improving the flash flood frequency analysis applying dendrogeomorphological evidences

    NASA Astrophysics Data System (ADS)

    Ruiz-Villanueva, V.; Ballesteros, J. A.; Bodoque, J. M.; Stoffel, M.; Bollschweiler, M.; Díez-Herrero, A.

    2009-09-01

    Flash floods are one of the natural hazards that cause major damages worldwide. Especially in Mediterranean areas they provoke high economic losses every year. In mountain areas with high stream gradients, floods events are characterized by extremely high flow and debris transport rates. Flash flood analysis in mountain areas presents specific scientific challenges. On one hand, there is a lack of information on precipitation and discharge due to a lack of spatially well distributed gauge stations with long records. On the other hand, gauge stations may not record correctly during extreme events when they are damaged or the discharge exceeds the recordable level. In this case, no systematic data allows improvement of the understanding of the spatial and temporal occurrence of the process. Since historic documentation is normally scarce or even completely missing in mountain areas, tree-ring analysis can provide an alternative approach. Flash floods may influence trees in different ways: (1) tilting of the stem through the unilateral pressure of the flowing mass or individual boulders; (2) root exposure through erosion of the banks; (3) injuries and scars caused by boulders and wood transported in the flow; (4) decapitation of the stem and resulting candelabra growth through the severe impact of boulders; (5) stem burial through deposition of material. The trees react to these disturbances with specific growth changes such as abrupt change of the yearly increment and anatomical changes like reaction wood or callus tissue. In this study, we sampled 90 cross sections and 265 increment cores of trees heavily affected by past flash floods in order to date past events and to reconstruct recurrence intervals in two torrent channels located in the Spanish Central System. The first study site is located along the Pelayo River, a torrent in natural conditions. Based on the external disturbances of trees and their geomorphological position, 114 Pinus pinaster (Ait

  14. CONVEYOR SYSTEM SAFETY ANALYSIS

    SciTech Connect

    M. Salem

    1995-06-23

    The purpose and objective of this analysis is to systematically identify and evaluate hazards related to the Yucca Mountain Project Exploratory Studies Facility (ESF) surface and subsurface conveyor system (for a list of conveyor subsystems see section 3). This process is an integral part of the systems engineering process; whereby safety is considered during planning, design, testing, and construction. A largely qualitative approach was used since a radiological System Safety Analysis is not required. The risk assessment in this analysis characterizes the accident scenarios associated with the conveyor structures/systems/components in terms of relative risk and includes recommendations for mitigating all identified risks. The priority for recommending and implementing mitigation control features is: (1) Incorporate measures to reduce risks and hazards into the structure/system/component (S/S/C) design, (2) add safety devices and capabilities to the designs that reduce risk, (3) provide devices that detect and warn personnel of hazardous conditions, and (4) develop procedures and conduct training to increase worker awareness of potential hazards, on methods to reduce exposure to hazards, and on the actions required to avoid accidents or correct hazardous conditions. The scope of this analysis is limited to the hazards related to the design of conveyor structures/systems/components (S/S/Cs) that occur during normal operation. Hazards occurring during assembly, test and maintenance or ''off normal'' operations have not been included in this analysis. Construction related work activities are specifically excluded per DOE Order 5481.1B section 4. c.

  15. Object-oriented fault tree models applied to system diagnosis

    NASA Technical Reports Server (NTRS)

    Iverson, David L.; Patterson-Hine, F. A.

    1990-01-01

    When a diagnosis system is used in a dynamic environment, such as the distributed computer system planned for use on Space Station Freedom, it must execute quickly and its knowledge base must be easily updated. Representing system knowledge as object-oriented augmented fault trees provides both features. The diagnosis system described here is based on the failure cause identification process of the diagnostic system described by Narayanan and Viswanadham. Their system has been enhanced in this implementation by replacing the knowledge base of if-then rules with an object-oriented fault tree representation. This allows the system to perform its task much faster and facilitates dynamic updating of the knowledge base in a changing diagnosis environment. Accessing the information contained in the objects is more efficient than performing a lookup operation on an indexed rule base. Additionally, the object-oriented fault trees can be easily updated to represent current system status. This paper describes the fault tree representation, the diagnosis algorithm extensions, and an example application of this system. Comparisons are made between the object-oriented fault tree knowledge structure solution and one implementation of a rule-based solution. Plans for future work on this system are also discussed.

  16. Applying Qualitative Hazard Analysis to Support Quantitative Safety Analysis for Proposed Reduced Wake Separation Conops

    NASA Technical Reports Server (NTRS)

    Shortle, John F.; Allocco, Michael

    2005-01-01

    This paper describes a scenario-driven hazard analysis process to identify, eliminate, and control safety-related risks. Within this process, we develop selective criteria to determine the applicability of applying engineering modeling to hypothesized hazard scenarios. This provides a basis for evaluating and prioritizing the scenarios as candidates for further quantitative analysis. We have applied this methodology to proposed concepts of operations for reduced wake separation for closely spaced parallel runways. For arrivals, the process identified 43 core hazard scenarios. Of these, we classified 12 as appropriate for further quantitative modeling, 24 that should be mitigated through controls, recommendations, and / or procedures (that is, scenarios not appropriate for quantitative modeling), and 7 that have the lowest priority for further analysis.

  17. Neutron-activation analysis applied to copper ores and artifacts

    NASA Technical Reports Server (NTRS)

    Linder, N. F.

    1970-01-01

    Neutron activation analysis is used for quantitative identification of trace metals in copper. Establishing a unique fingerprint of impurities in Michigan copper would enable identification of artifacts made from this copper.

  18. PIXE measurement applied to trace elemental analysis of human tissues

    NASA Astrophysics Data System (ADS)

    Tanaka, M.; Matsugi, E.; Miyasaki, K.; Yamagata, T.; Inoue, M.; Ogata, H.; Shimoura, S.

    1987-03-01

    PIXE measurement was applied for trace elemental analyses of 40 autoptic human kidneys. To investigate the reproducibility of the PIXE data, 9 targets obtained from one human liver were examined. The targets were prepared by wet-digestion using nitric and sulfuric acid. Yttrium was used as an internal standard. The extracted elemental concentrations for K, Fe, Cu, Zn, and Cd were in reasonable agreement with those obtained by atomic absorption spectrometry (AAS) and flame photometry (FP). Various correlations among the elements K, Ca, Cr, Mn, Fe, Ni, Cu, Zn, Rb, and Cd were examined individually for the renal cortex and renal medulla.

  19. Applying Language Systems to the Teaching of Writing.

    ERIC Educational Resources Information Center

    Jordan, Michael P.

    1986-01-01

    Uses a single language system--technical description--to illustrate how language systems can now be used as the basis for instruction in technical writing. Provides sample exercises in progressive teaching from simple description to complex continuity devices, showing how they can be used at all stages of the writing process. (HTH)

  20. Systems Biology Applied to Heart Failure With Normal Ejection Fraction

    PubMed Central

    Mesquita, Evandro Tinoco; Jorge, Antonio Jose Lagoeiro; de Souza, Celso Vale; Cassino, João Paulo Pedroza

    2014-01-01

    Heart failure with normal ejection fraction (HFNEF) is currently the most prevalent clinical phenotype of heart failure. However, the treatments available have shown no reduction in mortality so far. Advances in the omics sciences and techniques of high data processing used in molecular biology have enabled the development of an integrating approach to HFNEF based on systems biology. This study aimed at presenting a systems-biology-based HFNEF model using the bottom-up and top-down approaches. A literature search was conducted for studies published between 1991 and 2013 regarding HFNEF pathophysiology, its biomarkers and systems biology. A conceptual model was developed using bottom-up and top-down approaches of systems biology. The use of systems-biology approaches for HFNEF, a complex clinical syndrome, can be useful to better understand its pathophysiology and to discover new therapeutic targets. PMID:24918915

  1. Distribution patterns of entomopathogenic nematodes applied through drip irrigation systems.

    PubMed

    Wennemann, L; Cone, W W; Wright, L C; Perez, J; Conant, M M

    2003-04-01

    The distribution of entomopathogenic nematodes applied by drip irrigation was evaluated by injecting small volumes of Steinernema carpocapsae (Weiser) All strain, Steinernema feltiae (Filipjev) SN strain, Steinernema glaseri Steiner, and Heterorhabditis bacteriophora HP 88 strain Poinar suspensions into drip irrigation lines. Additionally, Steinernema riobrave Cabanillas, Poinar, & Raulston, and S. carpocapsae were injected in a 10-liter volume of water with an injection pump. Overall, the nematodes were evenly distributed along the drip lines. The total number of nematodes recovered from drip emitters was variable ranging from 42 to 92%. However, drip irrigation lines have potential to deliver entomopathogenic nematodes efficiently into pest habitats.

  2. GPS ensemble analysis applied to Antarctic vertical velocities

    NASA Astrophysics Data System (ADS)

    Petrie, E. J.; Clarke, P. J.; King, M. A.; Williams, S. D. P.

    2014-12-01

    GPS data is used to provide estimates of vertical land motion caused by e.g. glacial isostatic adjustment (GIA) and hydrologic loading. The vertical velocities estimated from the GPS data are often assimilated into GIA models or used for comparison purposes. GIA models are very important as they provide time-variable gravity corrections needed to estimate ice mass change over Greenland and Antarctica. While state-of-the art global GPS analysis has previously been performed for many Antarctic sites, formal errors in the resulting site velocities are typically obtained from noise analysis of each individual time series without consideration of processing or metadata issues. Here we present analysis of the results from two full global runs including a variety of parameter and reference frame alignment choices, and compare the results to previous work with a view to assessing if the size of the formal errors from the standard method is truly representative.

  3. Applying New Network Security Technologies to SCADA Systems.

    SciTech Connect

    Hurd, Steven A; Stamp, Jason Edwin; Duggan, David P; Chavez, Adrian R.

    2006-11-01

    Supervisory Control and Data Acquisition (SCADA) systems for automation are very important for critical infrastructure and manufacturing operations. They have been implemented to work in a number of physical environments using a variety of hardware, software, networking protocols, and communications technologies, often before security issues became of paramount concern. To offer solutions to security shortcomings in the short/medium term, this project was to identify technologies used to secure "traditional" IT networks and systems, and then assess their efficacy with respect to SCADA systems. These proposed solutions must be relatively simple to implement, reliable, and acceptable to SCADA owners and operators. 4This page intentionally left blank.

  4. [Dichotomizing method applied to calculating equilibrium constant of dimerization system].

    PubMed

    Cheng, Guo-zhong; Ye, Zhi-xiang

    2002-06-01

    The arbitrary trivariate algebraic equations are formed based on the combination principle. The univariata algebraic equation of equilibrium constant kappa for dimerization system is obtained through a series of algebraic transformation, and it depends on the properties of monotonic functions whether the equation is solvable or not. If the equation is solvable, equilibrium constant of dimerization system is obtained by dichotomy and its final equilibrium constant of dimerization system is determined according to the principle of error of fitting. The equilibrium constants of trisulfophthalocyanine and biosulfophthalocyanine obtained with this method are 47,973.4 and 30,271.8 respectively. The results are much better than those reported previously.

  5. Aircraft Electric Propulsion Systems Applied Research at NASA

    NASA Technical Reports Server (NTRS)

    Clarke, Sean

    2015-01-01

    Researchers at NASA are investigating the potential for electric propulsion systems to revolutionize the design of aircraft from the small-scale general aviation sector to commuter and transport-class vehicles. Electric propulsion provides new degrees of design freedom that may enable opportunities for tightly coupled design and optimization of the propulsion system with the aircraft structure and control systems. This could lead to extraordinary reductions in ownership and operating costs, greenhouse gas emissions, and noise annoyance levels. We are building testbeds, high-fidelity aircraft simulations, and the first highly distributed electric inhabited flight test vehicle to begin to explore these opportunities.

  6. EG&G Mound Applied Technologies payroll system

    SciTech Connect

    Not Available

    1992-02-07

    EG&G Mound Applied Technologies, Inc., manages and operates the Mound Facility, Miamisburg, Ohio, under a cost-plus-award-fee contract administered by the Department of Energy`s Albuquerque Field Office. The contractor`s Payroll Department is responsible for prompt payment in the proper amount to all persons entitled to be paid, in compliance with applicable laws, regulations, and legal decisions. The objective was to determine whether controls were in place to avoid erroneous payroll payments. EG&G Mound Applied Technologies, Inc., did not have all the internal controls required by General Accounting Office Title 6, ``Pay, Leave, and Allowances.`` Specifically, they did not have computerized edits, separation of duties and responsibilities, and restricted access to payroll data files. This condition occurred because its managers were not aware of Title 6 requirements. As a result, the contractor could not assure the Department of Energy that payroll costs were processes accurately; and fraud, waste, or abuse of Department of Energy funds could go undetected. Our sample of 212 payroll transactions from a population of 66,000 in FY 1991 disclosed only two minor processing errors and no instances of fraud, waste or abuse.

  7. Applied estimation for hybrid dynamical systems using perceptional information

    NASA Astrophysics Data System (ADS)

    Plotnik, Aaron M.

    This dissertation uses the motivating example of robotic tracking of mobile deep ocean animals to present innovations in robotic perception and estimation for hybrid dynamical systems. An approach to estimation for hybrid systems is presented that utilizes uncertain perceptional information about the system's mode to improve tracking of its mode and continuous states. This results in significant improvements in situations where previously reported methods of estimation for hybrid systems perform poorly due to poor distinguishability of the modes. The specific application that motivates this research is an automatic underwater robotic observation system that follows and films individual deep ocean animals. A first version of such a system has been developed jointly by the Stanford Aerospace Robotics Laboratory and Monterey Bay Aquarium Research Institute (MBARI). This robotic observation system is successfully fielded on MBARI's ROVs, but agile specimens often evade the system. When a human ROV pilot performs this task, one advantage that he has over the robotic observation system in these situations is the ability to use visual perceptional information about the target, immediately recognizing any changes in the specimen's behavior mode. With the approach of the human pilot in mind, a new version of the robotic observation system is proposed which is extended to (a) derive perceptional information (visual cues) about the behavior mode of the tracked specimen, and (b) merge this dissimilar, discrete and uncertain information with more traditional continuous noisy sensor data by extending existing algorithms for hybrid estimation. These performance enhancements are enabled by integrating techniques in hybrid estimation, computer vision and machine learning. First, real-time computer vision and classification algorithms extract a visual observation of the target's behavior mode. Existing hybrid estimation algorithms are extended to admit this uncertain but discrete

  8. System configured for applying multiple modifying agents to a substrate

    DOEpatents

    Propp, W. Alan; Argyle, Mark D.; Janikowski, Stuart K.; Fox, Robert V.; Toth, William J.; Ginosar, Daniel M.; Allen, Charles A.; Miller, David L.

    2003-11-25

    The present invention is related to the modifying of substrates with multiple modifying agents in a single continuous system. At least two processing chambers are configured for modifying the substrate in a continuous feed system. The processing chambers can be substantially isolated from one another by interstitial seals. Additionally, the two processing chambers can be substantially isolated from the surrounding atmosphere by end seals. Optionally, expansion chambers can be used to separate the seals from the processing chambers.

  9. System Configured For Applying Multiple Modifying Agents To A Substrate.

    DOEpatents

    Propp, W. Alan; Argyle, Mark D.; Janikowski, Stuart K.; Fox, Robert V.; Toth, William J.; Ginosar, Daniel M.; Allen, Charles A.; Miller, David L.

    2005-11-08

    The present invention is related to the modifying of substrates with multiple modifying agents in a single continuous system. At least two processing chambers are configured for modifying the substrate in a continuous feed system. The processing chambers can be substantially isolated from one another by interstitial seals. Additionally, the two processing chambers can be substantially isolated from the surrounding atmosphere by end seals. Optionally, expansion chambers can be used to separate the seals from the processing chambers.

  10. Calibration and investigation of infrared camera systems applying blackbody radiation

    NASA Astrophysics Data System (ADS)

    Hartmann, Juergen; Fischer, Joachim

    2001-03-01

    An experimental facility is presented, which allows calibration and detailed investigation of infrared camera systems. Various blackbodies operating in the temperature range from -60 degree(s)C up to 3000 degree(s)C serve as standard radiation sources, enabling calibration of camera systems in a wide temperature and spectral range with highest accuracy. Quantitative results and precise long-term investigations, especially in detecting climatic trends, require accurate traceability to the International Temperature Scale of 1990 (ITS-90). For the used blackbodies the traceability to ITS- 90 is either realized by standard platinum resistance thermometers (in the temperature range below 962 degree(s)C) or by absolute and relative radiometry (in the temperature range above 962 degree(s)C). This traceability is fundamental for implementation of quality assurance systems and realization of different standardizations, for example according ISO 9000. For investigation of the angular and the temperature resolution our set-up enables minimum resolvable (MRTD) and minimum detectable temperature difference (MDTD) measurements in the various temperature ranges. A collimator system may be used to image the MRTD and MDTD targets to infinity. As internal calibration of infrared camera systems critically depends on the temperature of the surrounding, the calibration and investigation of the cameras is performed in a climate box, which allows a detailed controlling of the environmental parameters like humidity and temperature. Experimental results obtained for different camera systems are presented and discussed.

  11. Action, Content and Identity in Applied Genre Analysis for ESP

    ERIC Educational Resources Information Center

    Flowerdew, John

    2011-01-01

    Genres are staged, structured, communicative events, motivated by various communicative purposes, and performed by members of specific discourse communities (Swales 1990; Bhatia 1993, 2004; Berkenkotter & Huckin 1995). Since its inception, with the two seminal works on the topic by Swales (1990) and Bhatia (1993), genre analysis has taken pride of…

  12. Applying Adult Learning Theory through a Character Analysis

    ERIC Educational Resources Information Center

    Baskas, Richard S.

    2011-01-01

    The purpose of this study is to analyze the behavior of a character, Celie, in a movie, 'The Color Purple," through the lens of two adult learning theorists to determine the relationships the character has with each theory. The development and portrayal of characters in movies can be explained and understood by the analysis of adult learning…

  13. Applying Skinner's Analysis of Verbal Behavior to Persons with Dementia

    ERIC Educational Resources Information Center

    Dixon, Mark; Baker, Jonathan C.; Sadowski, Katherine Ann

    2011-01-01

    Skinner's 1957 analysis of verbal behavior has demonstrated a fair amount of utility to teach language to children with autism and other various disorders. However, the learning of language can be forgotten, as is the case for many elderly suffering from dementia or other degenerative diseases. It appears possible that Skinner's operants may…

  14. Applying Score Analysis to a Rehearsal Pedagogy of Expressive Performance

    ERIC Educational Resources Information Center

    Byo, James L.

    2014-01-01

    The discoveries of score analysis (e.g., minor seventh chord, ostinato, phrase elision, melodic fragment, half cadence) are more than just compositional techniques or music vocabulary. They are sounds--fascinating, storytelling, dynamic modes of expression--that when approached as such enrich the rehearsal experience. This article presents a…

  15. Best practices: applying management analysis of excellence to immunization.

    PubMed

    Wishner, Amy; Aronson, Jerold; Kohrt, Alan; Norton, Gary

    2005-01-01

    The authors applied business management tools to analyze and promote excellence and to evaluate differences between average and above-average immunization peformers in private practices. The authors conducted a pilot study of 10 private practices in Pennsylvania using tools common in management to assess practices' organizational climate and managerial style. Authoritative and coaching styles of physician leaders were common to both groups. Managerial styles that emphasized higher levels of clarity and responsibility managerial styles were evident in the large practices; and rewards and flexibility styles were higher in the small above-average practices. The findings of this pilot study match results seen in high performers in other industries. It concludes that the authoritative style appears to have the most impact on performance. It has interesting implications for training/behavior change to improve immunization rates, along with traditional medical interventions.

  16. A value analysis model applied to the management of amblyopia.

    PubMed Central

    Beauchamp, G R; Bane, M C; Stager, D R; Berry, P M; Wright, W W

    1999-01-01

    PURPOSE: To assess the value of amblyopia-related services by utilizing a health value model (HVM). Cost and quality criteria are evaluated in accordance with the interests of patients, physicians, and purchasers. METHODS: We applied an HVM to a hypothetical statistical ("median") child with amblyopia whose visual acuity is 20/80 and to a group of children with amblyopia who are managed by our practice. We applied the model to calculate the value of these services by evaluating the responses of patients and physicians and relating these responses to clinical outcomes. RESULTS: The consensus value of care for the hypothetical median child was calculated to be 0.406 (of 1.000). For those children managed in our practice, the calculated value is 0.682. Clinically, 79% achieved 20/40 or better visual acuity, and the mean final visual acuity was 0.2 logMAR (20/32). Value appraisals revealed significant concerns about the financial aspects of amblyopia-related services, particularly among physicians. Patients rated services more positively than did physicians. CONCLUSIONS: Amblyopia care is difficult, sustained, and important work that requires substantial sensitivity to and support of children and families. Compliance and early detection are essential to success. The value of amblyopia services is rated significantly higher by patients than by physicians. Relative to the measured value, amblyopia care is undercompensated. The HVM is useful to appraise clinical service delivery and its variation. The costs of failure and the benefits of success are high; high-value amblyopia care yields substantial dividends and should be commensurately compensated in the marketplace. PMID:10703133

  17. Tributary Analysis Monitoring System

    NASA Technical Reports Server (NTRS)

    Woodard, Stanley, E. (Inventor); Coffey, Neil C. (Inventor); Taylor, Bryant D. (Inventor); Woodman, Keith L. (Inventor)

    2005-01-01

    A monitoring system for a fleet of vehicles includes at least one data acquisition and analysis module (DAAM) mounted on each vehicle in the fleet, a control module on each vehicle in communication with each DAAM, and terminal module located remotely with respect to the vehicles in the fleet. Each DAAM collects/analyzes sensor data to generate analysis results that identify the state of a plurality of systems of the vehicle. Each vehicle's control module collects/analyzes the analysis results from each onboard DAAM to generate vehicle status results that identify potential sources of vehicle anomalies. The terminal module collects/analyzes the analysis results and vehicle status results transmitted from each control module from the fleet of vehicles to identify multiple occurrences of vehicle anomalies and multiple occurrences of those vehicle systems operating at a performance level that is unacceptable. Results of the terminal module's analysis are provided to organizations responsible for the operation, maintenance and manufacturing of the vehicles in the fleet as well as the plurality of systems used in the fleet.

  18. Biomedical systems analysis program

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Biomedical monitoring programs which were developed to provide a system analysis context for a unified hypothesis for adaptation to space flight are presented and discussed. A real-time system of data analysis and decision making to assure the greatest possible crew safety and mission success is described. Information about man's abilities, limitations, and characteristic reactions to weightless space flight was analyzed and simulation models were developed. The predictive capabilities of simulation models for fluid-electrolyte regulation, erythropoiesis regulation, and calcium regulation are discussed.

  19. 40 CFR 63.8030 - What requirements apply to my heat exchange systems?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 13 2010-07-01 2010-07-01 false What requirements apply to my heat... apply to my heat exchange systems? (a) You must comply with the requirements specified in Table 6 to this subpart that apply to your heat exchange systems, except as specified in paragraphs (b) through...

  20. 40 CFR 63.8030 - What requirements apply to my heat exchange systems?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 13 2011-07-01 2011-07-01 false What requirements apply to my heat... apply to my heat exchange systems? (a) You must comply with the requirements specified in Table 6 to this subpart that apply to your heat exchange systems, except as specified in paragraphs (b) through...

  1. Cold-Applied Roofing Systems and Waterproofing and Dampproofing. Roofing Workbook and Tests.

    ERIC Educational Resources Information Center

    Brown, Arthur

    This workbook for students in California roofing apprenticeship programs provides information for classroom work in the area of cold-applied roofing systems and waterproofing and dampproofing. Eight topics are covered: introduction to cold-applied roofing systems and waterproofing and dampproofing, tools and equipment used in cold-applied roofing,…

  2. Applied Space Systems Engineering. Chapter 17; Manage Technical Data

    NASA Technical Reports Server (NTRS)

    Kent, Peter

    2008-01-01

    Effective space systems engineering (SSE) is conducted in a fully electronic manner. Competitive hardware, software, and system designs are created in a totally digital environment that enables rapid product design and manufacturing cycles, as well as a multitude of techniques such as modeling, simulation, and lean manufacturing that significantly reduce the lifecycle cost of systems. Because the SSE lifecycle depends on the digital environment, managing the enormous volumes of technical data needed to describe, build, deploy, and operate systems is a critical factor in the success of a project. This chapter presents the key aspects of Technical Data Management (TDM) within the SSE process. It is written from the perspective of the System Engineer tasked with establishing the TDM process and infrastructure for a major project. Additional perspectives are reflected from the point of view of the engineers on the project who work within the digital engineering environment established by the TDM toolset and infrastructure, and from the point of view of the contactors who interface via the TDM infrastructure. Table 17.1 lists the TDM process as it relates to SSE.

  3. Integrated hydrogen/oxygen technology applied to auxiliary propulsion systems

    NASA Technical Reports Server (NTRS)

    Gerhardt, David L.

    1990-01-01

    The purpose of the Integrated Hydrogen/Oxygen Technology (IHOT) study was to determine if the vehicle/mission needs and technology of the 1990's support development of an all cryogenic H2/O2 system. In order to accomplish this, IHOT adopted the approach of designing Integrated Auxiliary Propulsion Systems (IAPS) for a representative manned vehicle; the advanced manned launch system. The primary objectives were to develop IAPS concepts which appeared to offer viable alternatives to state-of-the-art (i.e., hypergolic, or earth-storable) APS approaches. The IHOT study resulted in the definition of three APS concepts; two cryogenic IAPS, and a third concept utilizing hypergolic propellants.

  4. Economical wind powered bioventing systems successfully applied at remote locations

    SciTech Connect

    Graves, D.; Klein, J.; Dillon, T. Jr.; Wilson, B.; Walker, K.

    1996-12-31

    Wind-powered bioventing systems were designed to operate at remote locations in the absence of electrical power. Laboratory measurements of soil respiration under bioventing conditions indicated the biodegradation of up to 25 mg of weathered diesel per kg of site soil per day. Further testing demonstrated the potential for harnessing wind-power to stimulate air movement through vadose zone soil. Several wind-powered bioventing systems were installed near Nome, Alaska. In situ respiration tests, soil gas composition measurements and measurable pressure changes in the soil indicated that the systems were capable of aerating the soil. Diesel range oil measurements indicated contaminant reductions up to 90% after only two treatments seasons. The results demonstrate the effectiveness of wind-powered biovents. The low cost, low maintenance, and simplicity of the biovents make them a very attractive treatment option for windy, remote sites with unsaturated soil impacted by biodegradable contaminants.

  5. Multi-agent cooperative systems applied to precision applications

    SciTech Connect

    McKay, M.D.; Anderson, M.O.; Gunderson, R.W.; Flann, N.; Abbott, B.

    1998-03-01

    Regulatory agencies are imposing limits and constraints to protect the operator and/or the environment. While generally necessary, these controls also tend to increase cost and decrease efficiency and productivity. Intelligent computer systems can be made to perform these hazardous tasks with greater efficiency and precision without danger to the operators. The Idaho national Engineering and Environmental Laboratory and the Center for Self-Organizing and Intelligent Systems at Utah State University have developed a series of autonomous all-terrain multi-agent systems capable of performing automated tasks within hazardous environments. This paper discusses the development and application of cooperative small-scale and large-scale robots for use in various activities associated with radiologically contaminated areas, prescription farming, and unexploded ordinances.

  6. Current Human Reliability Analysis Methods Applied to Computerized Procedures

    SciTech Connect

    Ronald L. Boring

    2012-06-01

    Computerized procedures (CPs) are an emerging technology within nuclear power plant control rooms. While CPs have been implemented internationally in advanced control rooms, to date no US nuclear power plant has implemented CPs in its main control room (Fink et al., 2009). Yet, CPs are a reality of new plant builds and are an area of considerable interest to existing plants, which see advantages in terms of enhanced ease of use and easier records management by omitting the need for updating hardcopy procedures. The overall intent of this paper is to provide a characterization of human reliability analysis (HRA) issues for computerized procedures. It is beyond the scope of this document to propose a new HRA approach or to recommend specific methods or refinements to those methods. Rather, this paper serves as a review of current HRA as it may be used for the analysis and review of computerized procedures.

  7. An Inverse Kinematic Approach Using Groebner Basis Theory Applied to Gait Cycle Analysis

    DTIC Science & Technology

    2013-03-01

    AN INVERSE KINEMATIC APPROACH USING GROEBNER BASIS THEORY APPLIED TO GAIT CYCLE ANALYSIS THESIS Anum Barki AFIT-ENP-13-M-02 DEPARTMENT OF THE AIR...copyright protection in the United States. AFIT-ENP-13-M-02 AN INVERSE KINEMATIC APPROACH USING GROEBNER BASIS THEORY APPLIED TO GAIT CYCLE ANALYSIS THESIS...APPROACH USING GROEBNER BASIS THEORY APPLIED TO GAIT CYCLE ANALYSIS Anum Barki, BS Approved: Dr. Ronald F. Tuttle (Chairman) Date Dr. Kimberly Kendricks

  8. Applying Cognitive Work Analysis to Time Critical Targeting Functionality

    DTIC Science & Technology

    2004-10-01

    Target List/Dynamic Target Queue (DTL/ DTQ ) in the same place. Figure 4-27 shows the task steps involved in achieving Goal 7. 4- 30 Figure 4-27...GUI WG to brainstorm the order of columns in the DTL/ DTQ Table, a critical component of the TCTF CUI, with successful results, which were...Cognitive Work Analysis DTD Display Task Description DTL/ DTQ Dynamic Target List/Dynamic Target Queue FDO Fighter Duty Officer FEBA Forward Edge

  9. Robust sliding mode control applied to double Inverted pendulum system

    SciTech Connect

    Mahjoub, Sonia; Derbel, Nabil; Mnif, Faical

    2009-03-05

    A three hierarchical sliding mode control is presented for a class of an underactuated system which can overcome the mismatched perturbations. The considered underactuated system is a double inverted pendulum (DIP), can be modeled by three subsystems. Such structure allows the construction of several designs of hierarchies for the controller. For all hierarchical designs, the asymptotic stability of every layer sliding mode surface and the sliding mode surface of subsystems are proved theoretically by Barbalat's lemma. Simulation results show the validity of these methods.

  10. Applying thiouracil (TU)-tagging for mouse transcriptome analysis

    PubMed Central

    Gay, Leslie; Karfilis, Kate V.; Miller, Michael R.; Doe, Chris Q.; Stankunas, Kryn

    2014-01-01

    Transcriptional profiling is a powerful approach to study mouse development, physiology, and disease models. Here, we describe a protocol for mouse thiouracil-tagging (TU-tagging), a transcriptome analysis technology that includes in vivo covalent labeling, purification, and analysis of cell type-specific RNA. TU-tagging enables 1) the isolation of RNA from a given cell population of a complex tissue, avoiding transcriptional changes induced by cell isolation trauma, and 2) the identification of actively transcribed RNAs and not pre-existing transcripts. Therefore, in contrast to other cell-specific transcriptional profiling methods based on purification of tagged ribosomes or nuclei, TU-tagging provides a direct examination of transcriptional regulation. We describe how to: 1) deliver 4-thiouracil to transgenic mice to thio-label cell lineage-specific transcripts, 2) purify TU-tagged RNA and prepare libraries for Illumina sequencing, and 3) follow a straight-forward bioinformatics workflow to identify cell type-enriched or differentially expressed genes. Tissue containing TU-tagged RNA can be obtained in one day, RNA-Seq libraries generated within two days, and, following sequencing, an initial bioinformatics analysis completed in one additional day. PMID:24457332

  11. AIRS FPA applied to the MIRIADS: powerful infrared systems applications

    NASA Astrophysics Data System (ADS)

    Caulfield, John T.; McCarley, Paul L.; Baxter, Christopher R.; Massie, Mark A.

    2001-10-01

    Raytheon's Infrared Operations (RIO) has invented and developed a new type of focal plane array with 'Image Processing on-the-chip' named the Adaptive IR Sensor (AIRS). The AIRS FPA is based upon the human retina in that it performs signal processing near the photoreceptors. The AIRS FPA has been reduced to practice and adaptively removes detector and optic temperature drift and 1/f induced fixed pattern noise. This 3rd-generation multi-mode IRFPA, also called a Smart FPA, is a 256 X 256-array format capable of operation in four modes: (1) Direct Injection (DI), (2) Adaptive Non-uniformity Correction (NUC), (3) Motion/Edge Detection, and (4) Subframe Averaging. Nova Research has developed a Modular IR Application Development System (MIRIADS) which is a compact single board camera system that is highly integrated with the dewar assembly. The MIRIADS system coupled with the AIRS Smart FPA results in a very high performance wide field of view IR Sensor and processing system with integrated in one of the smallest packages to date.

  12. System Identification and POD Method Applied to Unsteady Aerodynamics

    NASA Technical Reports Server (NTRS)

    Tang, Deman; Kholodar, Denis; Juang, Jer-Nan; Dowell, Earl H.

    2001-01-01

    The representation of unsteady aerodynamic flow fields in terms of global aerodynamic modes has proven to be a useful method for reducing the size of the aerodynamic model over those representations that use local variables at discrete grid points in the flow field. Eigenmodes and Proper Orthogonal Decomposition (POD) modes have been used for this purpose with good effect. This suggests that system identification models may also be used to represent the aerodynamic flow field. Implicit in the use of a systems identification technique is the notion that a relative small state space model can be useful in describing a dynamical system. The POD model is first used to show that indeed a reduced order model can be obtained from a much larger numerical aerodynamical model (the vortex lattice method is used for illustrative purposes) and the results from the POD and the system identification methods are then compared. For the example considered, the two methods are shown to give comparable results in terms of accuracy and reduced model size. The advantages and limitations of each approach are briefly discussed. Both appear promising and complementary in their characteristics.

  13. Response deprivation and reinforcement in applied settings: A preliminary analysis

    PubMed Central

    Konarski, Edward A.; Johnson, Moses R.; Crowell, Charles R.; Whitman, Thomas L.

    1980-01-01

    First-grade children engaged in seatwork behaviors under reinforcement schedules established according to the Premack Principle and the Response Deprivation Hypothesis. Across two experiments, schedules were presented to the children in a counter-balanced fashion which fulfilled the conditions of one, both, or neither of the hypotheses. Duration of on-task math and coloring in Experiment 1 and on-task math and reading in Experiment 2 were the dependent variables. A modified ABA-type withdrawal design, including a condition to control for the noncontingent effects of a schedule, indicated an increase of on-task instrumental responding only in those schedules where the condition of response deprivation was present but not where it was absent, regardless of the probability differential between the instrumental and contingent responses. These results were consistent with laboratory findings supporting the necessity of response deprivation for producing the reinforcement effect in single response, instrumental schedules. However, the results of the control procedure were equivocal so the contribution of the contingent relationship between the responses to the increases in instrumental behavior could not be determined. Nevertheless, these results provided tentative support for the Response Deprivation Hypothesis as a new approach to establishing reinforcement schedules while indicating the need for further research in this area. The possible advantages of this technique for applied use were identified and discussed. PMID:16795635

  14. Automated synchrogram analysis applied to heartbeat and reconstructed respiration

    NASA Astrophysics Data System (ADS)

    Hamann, Claudia; Bartsch, Ronny P.; Schumann, Aicko Y.; Penzel, Thomas; Havlin, Shlomo; Kantelhardt, Jan W.

    2009-03-01

    Phase synchronization between two weakly coupled oscillators has been studied in chaotic systems for a long time. However, it is difficult to unambiguously detect such synchronization in experimental data from complex physiological systems. In this paper we review our study of phase synchronization between heartbeat and respiration in 150 healthy subjects during sleep using an automated procedure for screening the synchrograms. We found that this synchronization is significantly enhanced during non-rapid-eye-movement (non-REM) sleep (deep sleep and light sleep) and is reduced during REM sleep. In addition, we show that the respiration signal can be reconstructed from the heartbeat recordings in many subjects. Our reconstruction procedure, which works particularly well during non-REM sleep, allows the detection of cardiorespiratory synchronization even if only heartbeat intervals were recorded.

  15. Applying temporal network analysis to the venture capital market

    NASA Astrophysics Data System (ADS)

    Zhang, Xin; Feng, Ling; Zhu, Rongqian; Stanley, H. Eugene

    2015-10-01

    Using complex network theory to study the investment relationships of venture capital firms has produced a number of significant results. However, previous studies have often neglected the temporal properties of those relationships, which in real-world scenarios play a pivotal role. Here we examine the time-evolving dynamics of venture capital investment in China by constructing temporal networks to represent (i) investment relationships between venture capital firms and portfolio companies and (ii) the syndication ties between venture capital investors. The evolution of the networks exhibits rich variations in centrality, connectivity and local topology. We demonstrate that a temporal network approach provides a dynamic and comprehensive analysis of real-world networks.

  16. Applied analysis/computational mathematics. Final report 1993

    SciTech Connect

    Lax, P.; Berger, M.

    1993-12-01

    This is the final report for the Courant Mathematics and Computing Laboratory (CMCL) research program for the years 1991--1993. Our research efforts encompass the formulation of physical problems in terms of mathematical models (both old and new), the mathematical analysis of such models, and their numerical resolution. This last step involves the development and implementation of efficient methods for large scale computation. Our analytic and numerical work often go hand in hand; new theoretical approaches often have numerical counterparts, while numerical experimentation often suggests avenues for analytical investigation.

  17. Inconsistencies in the harmonic analysis applied to pulsating stars

    NASA Astrophysics Data System (ADS)

    Pascual-Granado, J.; Garrido, R.; Suárez, J. C.

    2015-05-01

    Harmonic analysis is the fundamental mathematical method used for the identification of pulsation frequencies in asteroseismology and other fields of physics. Here we introduce a test to evaluate the validity of the hypothesis in which Fourier theorem is based: the convergence of the expansion series. The huge number of difficulties found in the interpretation of the periodograms of pulsating stars observed by CoRoT and Kepler satellites lead us to test whether the function underlying these time series is analytic or not. Surprisingly, the main result is that these are originated from non-analytic functions, therefore, the condition for Parseval's theorem is not guaranteed.

  18. Arctic Climate Systems Analysis

    SciTech Connect

    Ivey, Mark D.; Robinson, David G.; Boslough, Mark B.; Backus, George A.; Peterson, Kara J.; van Bloemen Waanders, Bart G.; Swiler, Laura Painton; Desilets, Darin Maurice; Reinert, Rhonda Karen

    2015-03-01

    This study began with a challenge from program area managers at Sandia National Laboratories to technical staff in the energy, climate, and infrastructure security areas: apply a systems-level perspective to existing science and technology program areas in order to determine technology gaps, identify new technical capabilities at Sandia that could be applied to these areas, and identify opportunities for innovation. The Arctic was selected as one of these areas for systems level analyses, and this report documents the results. In this study, an emphasis was placed on the arctic atmosphere since Sandia has been active in atmospheric research in the Arctic since 1997. This study begins with a discussion of the challenges and benefits of analyzing the Arctic as a system. It goes on to discuss current and future needs of the defense, scientific, energy, and intelligence communities for more comprehensive data products related to the Arctic; assess the current state of atmospheric measurement resources available for the Arctic; and explain how the capabilities at Sandia National Laboratories can be used to address the identified technological, data, and modeling needs of the defense, scientific, energy, and intelligence communities for Arctic support.

  19. VENTILATION TECHNOLOGY SYSTEMS ANALYSIS

    EPA Science Inventory

    The report gives results of a project to develop a systems analysis of ventilation technology and provide a state-of-the-art assessment of ventilation and indoor air quality (IAQ) research needs. (NOTE: Ventilation technology is defined as the hardware necessary to bring outdoor ...

  20. Applying twisted boundary conditions for few-body nuclear systems

    NASA Astrophysics Data System (ADS)

    Körber, Christopher; Luu, Thomas

    2016-05-01

    We describe and implement twisted boundary conditions for the deuteron and triton systems within finite volumes using the nuclear lattice EFT formalism. We investigate the finite-volume dependence of these systems with different twist angles. We demonstrate how various finite-volume information can be used to improve calculations of binding energies in such a framework. Our results suggests that with appropriate twisting of boundaries, infinite-volume binding energies can be reliably extracted from calculations using modest volume sizes with cubic length L ≈8 -14 fm. Of particular importance is our derivation and numerical verification of three-body analogs of "i-periodic" twist angles that eliminate the leading-order finite-volume effects to the three-body binding energy.

  1. Parabolic dish systems at work - Applying the concepts

    NASA Technical Reports Server (NTRS)

    Marriott, A. T.

    1981-01-01

    An overview is given of parabolic dish solar concentrator application experiments being conducted by the U.S. Department of Energy. The 'engineering experiments' comprise the testing of (1) a small-community powerplant system, in conjunction with a grid-connected utility; (2) stand-alone applications at remote sites such as military installations, radar stations and villages; and (3) dish modules that can deliver heat for direct use in industrial processes. Applicability projections are based on a dish and receiver that use a Brayton engine with an engine/generator efficiency of 25% and a production level of up to 25,000 units per year. Analyses indicate that parabolic-dish power systems can potentially replace small, oil-fired power plants in all regions of the U.S. between 1985 and 1991.

  2. Applying Contamination Modelling to Spacecraft Propulsion Systems Designs and Operations

    NASA Technical Reports Server (NTRS)

    Chen, Philip T.; Thomson, Shaun; Woronowicz, Michael S.

    2000-01-01

    Molecular and particulate contaminants generated from the operations of a propulsion system may impinge on spacecraft critical surfaces. Plume depositions or clouds may hinder the spacecraft and instruments from performing normal operations. Firing thrusters will generate both molecular and particulate contaminants. How to minimize the contamination impact from the plume becomes very critical for a successful mission. The resulting effect from either molecular or particulate contamination of the thruster firing is very distinct. This paper will discuss the interconnection between the functions of spacecraft contamination modeling and propulsion system implementation. The paper will address an innovative contamination engineering approach implemented from the spacecraft concept design, manufacturing, integration and test (I&T), launch, to on- orbit operations. This paper will also summarize the implementation on several successful missions. Despite other contamination sources, only molecular contamination will be considered here.

  3. Simulation program of nonlinearities applied to telecommunication systems

    NASA Technical Reports Server (NTRS)

    Thomas, C.

    1979-01-01

    In any satellite communication system, the problems of distorsion created by nonlinear devices or systems must be considered. The subject of this paper is the use of the Fast Fourier Transform (F.F.T.) in the prediction of the intermodulation performance of amplifiers, mixers, filters. A nonlinear memory-less model is chosen to simulate amplitude and phase nonlinearities of the device in the simulation program written in FORTRAN 4. The experimentally observed nonlinearity parameters of a low noise 3.7-4.2 GHz amplifier are related to the gain and phase coefficients of Fourier Service Series. The measured results are compared with those calculated from the simulation in the cases where the input signal is composed of two, three carriers and noise power density.

  4. Nonlinear Waves, Dynamical Systems and Other Applied Mathematics Programs

    DTIC Science & Technology

    1991-10-04

    present a general scheme of perturbation method for perturbed soliton systems, based on the normal form theory and the method of multiple scales. By this...dimension, and discuss possible consequences of the interplay between wavefront- interactions and curvature in two dimensions. Thursday, October 19 All ... normal speed D parametrized by the local mean surface curvature x. Its solution provides a relation D = D(x) which determines the evolution of the front

  5. Multivariate calibration applied to the quantitative analysis of infrared spectra

    SciTech Connect

    Haaland, D.M.

    1991-01-01

    Multivariate calibration methods are very useful for improving the precision, accuracy, and reliability of quantitative spectral analyses. Spectroscopists can more effectively use these sophisticated statistical tools if they have a qualitative understanding of the techniques involved. A qualitative picture of the factor analysis multivariate calibration methods of partial least squares (PLS) and principal component regression (PCR) is presented using infrared calibrations based upon spectra of phosphosilicate glass thin films on silicon wafers. Comparisons of the relative prediction abilities of four different multivariate calibration methods are given based on Monte Carlo simulations of spectral calibration and prediction data. The success of multivariate spectral calibrations is demonstrated for several quantitative infrared studies. The infrared absorption and emission spectra of thin-film dielectrics used in the manufacture of microelectronic devices demonstrate rapid, nondestructive at-line and in-situ analyses using PLS calibrations. Finally, the application of multivariate spectral calibrations to reagentless analysis of blood is presented. We have found that the determination of glucose in whole blood taken from diabetics can be precisely monitored from the PLS calibration of either mind- or near-infrared spectra of the blood. Progress toward the non-invasive determination of glucose levels in diabetics is an ultimate goal of this research. 13 refs., 4 figs.

  6. Unsupervised feature relevance analysis applied to improve ECG heartbeat clustering.

    PubMed

    Rodríguez-Sotelo, J L; Peluffo-Ordoñez, D; Cuesta-Frau, D; Castellanos-Domínguez, G

    2012-10-01

    The computer-assisted analysis of biomedical records has become an essential tool in clinical settings. However, current devices provide a growing amount of data that often exceeds the processing capacity of normal computers. As this amount of information rises, new demands for more efficient data extracting methods appear. This paper addresses the task of data mining in physiological records using a feature selection scheme. An unsupervised method based on relevance analysis is described. This scheme uses a least-squares optimization of the input feature matrix in a single iteration. The output of the algorithm is a feature weighting vector. The performance of the method was assessed using a heartbeat clustering test on real ECG records. The quantitative cluster validity measures yielded a correctly classified heartbeat rate of 98.69% (specificity), 85.88% (sensitivity) and 95.04% (general clustering performance), which is even higher than the performance achieved by other similar ECG clustering studies. The number of features was reduced on average from 100 to 18, and the temporal cost was a 43% lower than in previous ECG clustering schemes.

  7. Near-infrared radiation curable multilayer coating systems and methods for applying same

    DOEpatents

    Bowman, Mark P; Verdun, Shelley D; Post, Gordon L

    2015-04-28

    Multilayer coating systems, methods of applying and related substrates are disclosed. The coating system may comprise a first coating comprising a near-IR absorber, and a second coating deposited on a least a portion of the first coating. Methods of applying a multilayer coating composition to a substrate may comprise applying a first coating comprising a near-IR absorber, applying a second coating over at least a portion of the first coating and curing the coating with near infrared radiation.

  8. On applying continuous wavelet transform in wheeze analysis.

    PubMed

    Taplidou, Styliani A; Hadjileontiadis, Leontios J; Kitsas, Ilias K; Panoulas, Konstantinos I; Penzel, Thomas; Gross, Volker; Panas, Stavros M

    2004-01-01

    The identification of continuous abnormal lung sounds, like wheezes, in the total breathing cycle is of great importance in the diagnosis of obstructive airways pathologies. To this vein, the current work introduces an efficient method for the detection of wheezes, based on the time-scale representation of breath sound recordings. The employed Continuous Wavelet Transform is proven to be a valuable tool at this direction, when combined with scale-dependent thresholding. Analysis of lung sound recordings from 'wheezing' patients shows promising performance in the detection and extraction of wheezes from the background noise and reveals its potentiality for data-volume reduction in long-term wheezing screening, such as in sleep-laboratories.

  9. Applying Machine Learning to GlueX Data Analysis

    NASA Astrophysics Data System (ADS)

    Boettcher, Thomas

    2014-03-01

    GlueX is a high energy physics experiment with the goal of collecting data necessary for understanding confinement in quantum chromodynamics. Beginning in 2015, GlueX will collect huge amounts of data describing billions of particle collisions. In preparation for data collection, efforts are underway to develop a methodology for analyzing these large data sets. One of the primary challenges in GlueX data analysis is isolating events of interest from a proportionally large background. GlueX has recently begun approaching this selection problem using machine learning algorithms, specifically boosted decision trees. Preliminary studies indicate that these algorithms have the potential to offer vast improvements in both signal selection efficiency and purity over more traditional techniques.

  10. Downside Risk analysis applied to the Hedge Funds universe

    NASA Astrophysics Data System (ADS)

    Perelló, Josep

    2007-09-01

    Hedge Funds are considered as one of the portfolio management sectors which shows a fastest growing for the past decade. An optimal Hedge Fund management requires an appropriate risk metrics. The classic CAPM theory and its Ratio Sharpe fail to capture some crucial aspects due to the strong non-Gaussian character of Hedge Funds statistics. A possible way out to this problem while keeping the CAPM simplicity is the so-called Downside Risk analysis. One important benefit lies in distinguishing between good and bad returns, that is: returns greater or lower than investor's goal. We revisit most popular Downside Risk indicators and provide new analytical results on them. We compute these measures by taking the Credit Suisse/Tremont Investable Hedge Fund Index Data and with the Gaussian case as a benchmark. In this way, an unusual transversal lecture of the existing Downside Risk measures is provided.

  11. Applying Skinner's analysis of verbal behavior to persons with dementia.

    PubMed

    Dixon, Mark; Baker, Jonathan C; Sadowski, Katherine Ann

    2011-03-01

    Skinner's 1957 analysis of verbal behavior has demonstrated a fair amount of utility to teach language to children with autism and other various disorders. However, the learning of language can be forgotten, as is the case for many elderly suffering from dementia or other degenerative diseases. It appears possible that Skinner's operants may facilitate not only acquisition of language but also the ability to recall items or objects that may have appeared to be "forgotten." The present study examined the utility of having a series of adults in long-term care emit tacts, echoics, or intraverbals upon presentation of various visual stimuli. Compared to a no-verbal response condition, it appears that the incorporation of Skinner's verbal operants can in fact improve recall for this population. Implications for the retraining of lost language are presented.

  12. Geostatistical analysis as applied to two environmental radiometric time series.

    PubMed

    Dowdall, Mark; Lind, Bjørn; Gerland, Sebastian; Rudjord, Anne Liv

    2003-03-01

    This article details the results of an investigation into the application of geostatistical data analysis to two environmental radiometric time series. The data series employed consist of 99Tc values for seaweed (Fucus vesiculosus) and seawater samples taken as part of a marine monitoring program conducted on the coast of northern Norway by the Norwegian Radiation Protection Authority. Geostatistical methods were selected in order to provide information on values of the variables at unsampled times and to investigate the temporal correlation exhibited by the data sets. This information is of use in the optimisation of future sampling schemes and for providing information on the temporal behaviour of the variables in question that may not be obtained during a cursory analysis. The results indicate a high degree of temporal correlation within the data sets, the correlation for the seawater and seaweed data being modelled with an exponential and linear function, respectively. The semi-variogram for the seawater data indicates a temporal range of correlation of approximately 395 days with no apparent random component to the overall variance structure and was described best by an exponential function. The temporal structure of the seaweed data was best modelled by a linear function with a small nugget component. Evidence of drift was present in both semi-variograms. Interpolation of the data sets using the fitted models and a simple kriging procedure were compared, using a cross-validation procedure, with simple linear interpolation. Results of this exercise indicate that, for the seawater data, the kriging procedure outperformed the simple interpolation with respect to error distribution and correlation of estimates with actual values. Using the unbounded linear model with the seaweed data produced estimates that were only marginally better than those produced by the simple interpolation.

  13. An applied study using systems engineering methods to prioritize green systems options

    SciTech Connect

    Lee, Sonya M; Macdonald, John M

    2009-01-01

    For many years, there have been questions about the effectiveness of applying different green solutions. If you're building a home and wish to use green technologies, where do you start? While all technologies sound promising, which will perform the best over time? All this has to be considered within the cost and schedule of the project. The amount of information available on the topic can be overwhelming. We seek to examine if Systems Engineering methods can be used to help people choose and prioritize technologies that fit within their project and budget. Several methods are used to gain perspective into how to select the green technologies, such as the Analytic Hierarchy Process (AHP) and Kepner-Tregoe. In our study, subjects applied these methods to analyze cost, schedule, and trade-offs. Results will document whether the experimental approach is applicable to defining system priorities for green technologies.

  14. System And Method Of Applying Energetic Ions For Sterlization

    DOEpatents

    Schmidt, John A.

    2002-06-11

    A method of sterilization of a container is provided whereby a cold plasma is caused to be disposed near a surface to be sterilized, and the cold plasma is then subjected to a pulsed voltage differential for producing energized ions in the plasma. Those energized ions then operate to achieve spore destruction on the surface to be sterilized. Further, a system for sterilization of a container which includes a conductive or non-conductive container, a cold plasma in proximity to the container, and a high voltage source for delivering a pulsed voltage differential between an electrode and the container and across the cold plasma, is provided.

  15. System and method of applying energetic ions for sterilization

    DOEpatents

    Schmidt, John A.

    2003-12-23

    A method of sterilization of a container is provided whereby a cold plasma is caused to be disposed near a surface to be sterilized, and the cold plasma is then subjected to a pulsed voltage differential for producing energized ions in the plasma. Those energized ions then operate to achieve spore destruction on the surface to be sterilized. Further, a system for sterilization of a container which includes a conductive or non-conductive container, a cold plasma in proximity to the container, and a high voltage source for delivering a pulsed voltage differential between an electrode and the container and across the cold plasma, is provided.

  16. Application of acousto-optic actuator applied in holographic system

    NASA Astrophysics Data System (ADS)

    Ling, FuRi; Wang, Biao

    2002-09-01

    In this paper, we discuss acousto-optical scanning and deflection, and design an acousto-optical actuator for steering the laser beam in the direction of vertical and horizon. In this system a laser whose wavelength is 532 nm is used and is expanded by a cylindrical lens. This horizontal actuator produces the horizontal deflection and the spherical lens following the horizontal actuator rotates the beam to match the aperture of the vertical actuator. The cylindrical lens restores the beam to its original circular cross-section, after which the microscope optics brings it to a focus in the lithium niobate crystal in which we store information.

  17. Acton mass flow system applied to PFBC feed

    NASA Technical Reports Server (NTRS)

    Homburg, E.

    1977-01-01

    Dense phase pneumatic conveying and the Acton Mass Flow concept are defined with emphasis on the specific advantages to the coal and dolomite feed to the Pressurized Fluidized Bed Combustor. The transport and feed functions are explored with a comparison of designing the process for a combined function or for individual functions. The equipment required to accomplish these functions is described together with a typical example of sizing and air or gas requirements. A general outline of the control system required to obtain a uniform feed rate is provided. The condition of the coal and dolomite and conveying gas as required to obtain reliable transport and feed will be discussed.

  18. Applying Real Options for Evaluating Investments in ERP Systems

    NASA Astrophysics Data System (ADS)

    Nakagane, Jun; Sekozawa, Teruji

    This paper intends to verify effectiveness of real options approach for evaluating investments in Enterprise Resource Planning systems (ERP) and proves how important it is to disclose shadow options potentially embedded in ERP investment. The net present value (NPV) method is principally adopted to evaluate the value of ERP. However, the NPV method assumes no uncertainties exist in the object. It doesn't satisfy the current business circumstances which are filled with dynamic issues. Since the 1990s the effectiveness of option pricing models for Information System (IS) investment to solve issues in the NPV method has been discussed in the IS literature. This paper presents 3 business cases to review the practical advantages of such techniques for IS investments, especially ERP investments. The first case is EDI development. We evaluate the project by a new approach with lighting one of shadow options, EDI implementation. In the second case we reveal an ERP investment has an “expanding option” in a case of eliminating redundancy. The third case describes an option to contract which is deliberately slotted in ERP development to prepare transferring a manufacturing facility.

  19. Basic and Applied Aspects of Color Tuning of Bioluminescence Systems

    NASA Astrophysics Data System (ADS)

    Ohmiya, Yoshihiro

    2005-09-01

    V. Viviani et al. [Biochemistry 38 (1999) 8271] were the first to succeed in cloning the red-emitting enzyme from the South American railroad worm, which is the only bioluminescent organism known to emit a red-colored light. The application of red bioluminescence has been our goal because the transmittance of longer-wavelength light is superior to that of the other colors for visualization of biological functions in living cells. Now, different color luciferases, which emit with wavelength maxima ranging from 400 to 630 nm, are available and are being used. For example, based on different color luciferases, Nakajima et al. developed a tricolor reporter in vitro assay system based on these different color luciferases in which the expression of three genes can be monitored simultaneously. On the other hand, bioluminescence resonance energy transfer (BRET) is a natural phenomenon caused by the intermolecular interaction between a bioluminescent protein and a fluorophore on a second protein, resulting in the light from the bioluminescence reaction having the spectrum of the fluorophore. Otsuji et al. [Anal. Biochem. 329 (2004) 230] showed that the change in the efficiency of energy transfer in intramolecular BRET can quantify cellular functions in living cells. In this review, I introduce the basic mechanisms of color tuning in bioluminescent systems and new applications based on color tuning in the life sciences.

  20. Neptune Aerocapture Systems Analysis

    NASA Technical Reports Server (NTRS)

    Lockwood, Mary Kae

    2004-01-01

    A Neptune Aerocapture Systems Analysis is completed to determine the feasibility, benefit and risk of an aeroshell aerocapture system for Neptune and to identify technology gaps and technology performance goals. The high fidelity systems analysis is completed by a five center NASA team and includes the following disciplines and analyses: science; mission design; aeroshell configuration screening and definition; interplanetary navigation analyses; atmosphere modeling; computational fluid dynamics for aerodynamic performance and database definition; initial stability analyses; guidance development; atmospheric flight simulation; computational fluid dynamics and radiation analyses for aeroheating environment definition; thermal protection system design, concepts and sizing; mass properties; structures; spacecraft design and packaging; and mass sensitivities. Results show that aerocapture can deliver 1.4 times more mass to Neptune orbit than an all-propulsive system for the same launch vehicle. In addition aerocapture results in a 3-4 year reduction in trip time compared to all-propulsive systems. Aerocapture is feasible and performance is adequate for the Neptune aerocapture mission. Monte Carlo simulation results show 100% successful capture for all cases including conservative assumptions on atmosphere and navigation. Enabling technologies for this mission include TPS manufacturing; and aerothermodynamic methods and validation for determining coupled 3-D convection, radiation and ablation aeroheating rates and loads, and the effects on surface recession.

  1. Aerodynamic Reconstruction Applied to Parachute Test Vehicle Flight Data Analysis

    NASA Technical Reports Server (NTRS)

    Cassady, Leonard D.; Ray, Eric S.; Truong, Tuan H.

    2013-01-01

    The aerodynamics, both static and dynamic, of a test vehicle are critical to determining the performance of the parachute cluster in a drop test and for conducting a successful test. The Capsule Parachute Assembly System (CPAS) project is conducting tests of NASA's Orion Multi-Purpose Crew Vehicle (MPCV) parachutes at the Army Yuma Proving Ground utilizing the Parachute Test Vehicle (PTV). The PTV shape is based on the MPCV, but the height has been reduced in order to fit within the C-17 aircraft for extraction. Therefore, the aerodynamics of the PTV are similar, but not the same as, the MPCV. A small series of wind tunnel tests and computational fluid dynamics cases were run to modify the MPCV aerodynamic database for the PTV, but aerodynamic reconstruction of the flights has proven an effective source for further improvements to the database. The acceleration and rotational rates measured during free flight, before parachute inflation but during deployment, were used to con rm vehicle static aerodynamics. A multibody simulation is utilized to reconstruct the parachute portions of the flight. Aerodynamic or parachute parameters are adjusted in the simulation until the prediction reasonably matches the flight trajectory. Knowledge of the static aerodynamics is critical in the CPAS project because the parachute riser load measurements are scaled based on forebody drag. PTV dynamic damping is critical because the vehicle has no reaction control system to maintain attitude - the vehicle dynamics must be understood and modeled correctly before flight. It will be shown here that aerodynamic reconstruction has successfully contributed to the CPAS project.

  2. Applying data mining for the analysis of breast cancer data.

    PubMed

    Liou, Der-Ming; Chang, Wei-Pin

    2015-01-01

    Data mining, also known as Knowledge-Discovery in Databases (KDD), is the process of automatically searching large volumes of data for patterns. For instance, a clinical pattern might indicate a female who have diabetes or hypertension are easier suffered from stroke for 5 years in a future. Then, a physician can learn valuable knowledge from the data mining processes. Here, we present a study focused on the investigation of the application of artificial intelligence and data mining techniques to the prediction models of breast cancer. The artificial neural network, decision tree, logistic regression, and genetic algorithm were used for the comparative studies and the accuracy and positive predictive value of each algorithm were used as the evaluation indicators. 699 records acquired from the breast cancer patients at the University of Wisconsin, nine predictor variables, and one outcome variable were incorporated for the data analysis followed by the tenfold cross-validation. The results revealed that the accuracies of logistic regression model were 0.9434 (sensitivity 0.9716 and specificity 0.9482), the decision tree model 0.9434 (sensitivity 0.9615, specificity 0.9105), the neural network model 0.9502 (sensitivity 0.9628, specificity 0.9273), and the genetic algorithm model 0.9878 (sensitivity 1, specificity 0.9802). The accuracy of the genetic algorithm was significantly higher than the average predicted accuracy of 0.9612. The predicted outcome of the logistic regression model was higher than that of the neural network model but no significant difference was observed. The average predicted accuracy of the decision tree model was 0.9435 which was the lowest of all four predictive models. The standard deviation of the tenfold cross-validation was rather unreliable. This study indicated that the genetic algorithm model yielded better results than other data mining models for the analysis of the data of breast cancer patients in terms of the overall accuracy of

  3. Applied Climate-Change Analysis: The Climate Wizard Tool

    PubMed Central

    Girvetz, Evan H.; Zganjar, Chris; Raber, George T.; Maurer, Edwin P.; Kareiva, Peter; Lawler, Joshua J.

    2009-01-01

    Background Although the message of “global climate change” is catalyzing international action, it is local and regional changes that directly affect people and ecosystems and are of immediate concern to scientists, managers, and policy makers. A major barrier preventing informed climate-change adaptation planning is the difficulty accessing, analyzing, and interpreting climate-change information. To address this problem, we developed a powerful, yet easy to use, web-based tool called Climate Wizard (http://ClimateWizard.org) that provides non-climate specialists with simple analyses and innovative graphical depictions for conveying how climate has and is projected to change within specific geographic areas throughout the world. Methodology/Principal Findings To demonstrate the Climate Wizard, we explored historic trends and future departures (anomalies) in temperature and precipitation globally, and within specific latitudinal zones and countries. We found the greatest temperature increases during 1951–2002 occurred in northern hemisphere countries (especially during January–April), but the latitude of greatest temperature change varied throughout the year, sinusoidally ranging from approximately 50°N during February-March to 10°N during August-September. Precipitation decreases occurred most commonly in countries between 0–20°N, and increases mostly occurred outside of this latitudinal region. Similarly, a quantile ensemble analysis based on projections from 16 General Circulation Models (GCMs) for 2070–2099 identified the median projected change within countries, which showed both latitudinal and regional patterns in projected temperature and precipitation change. Conclusions/Significance The results of these analyses are consistent with those reported by the Intergovernmental Panel on Climate Change, but at the same time, they provide examples of how Climate Wizard can be used to explore regionally- and temporally-specific analyses of climate

  4. Applied Drama and the Higher Education Learning Spaces: A Reflective Analysis

    ERIC Educational Resources Information Center

    Moyo, Cletus

    2015-01-01

    This paper explores Applied Drama as a teaching approach in Higher Education learning spaces. The exploration takes a reflective analysis approach by first examining the impact that Applied Drama has had on my career as a Lecturer/Educator/Teacher working in Higher Education environments. My engagement with Applied Drama practice and theory is…

  5. Exploratory Factor Analysis as a Construct Validation Tool: (Mis)applications in Applied Linguistics Research

    ERIC Educational Resources Information Center

    Karami, Hossein

    2015-01-01

    Factor analysis has been frequently exploited in applied research to provide evidence about the underlying factors in various measurement instruments. A close inspection of a large number of studies published in leading applied linguistic journals shows that there is a misconception among applied linguists as to the relative merits of exploratory…

  6. Ion Beam Analysis applied to laser-generated plasmas

    NASA Astrophysics Data System (ADS)

    Cutroneo, M.; Macková, A.; Havranek, V.; Malinsky, P.; Torrisi, L.; Kormunda, M.; Barchuk, M.; Ullschmied, J.; Dudzak, R.

    2016-04-01

    This paper presents the research activity on Ion Beam Analysis methods performed at Tandetron Laboratory (LT) of the Institute of Nuclear Physics AS CR, Rez, Czech Republic. Recently, many groups are paying attention to implantation by laser generated plasma. This process allows to insert a controllable amount of energetic ions into the surface layers of different materials modifying the physical and chemical properties of the surface material. Different substrates are implanted by accelerated ions from plasma through terawatt iodine laser, at nominal intensity of 1015 W/cm2, at the PALS Research Infrastructure AS CR, in the Czech Republic. This regime of the laser matter interaction generates, multi-MeV proton beams, and multi-charged ions that are tightly confined in time (hundreds ps) and space (source radius of a few microns). These ion beams have a much lower transverse temperature, a much shorter duration and a much higher current than those obtainable from conventional accelerators. The implementation of protons and ions acceleration driven by ultra-short high intensity lasers is exhibited by adopting suitable irradiation conditions as well as tailored targets. An overview of implanted targets and their morphological and structural characterizations is presented and discussed.

  7. Applied and computational harmonic analysis on graphs and networks

    NASA Astrophysics Data System (ADS)

    Irion, Jeff; Saito, Naoki

    2015-09-01

    In recent years, the advent of new sensor technologies and social network infrastructure has provided huge opportunities and challenges for analyzing data recorded on such networks. In the case of data on regular lattices, computational harmonic analysis tools such as the Fourier and wavelet transforms have well-developed theories and proven track records of success. It is therefore quite important to extend such tools from the classical setting of regular lattices to the more general setting of graphs and networks. In this article, we first review basics of graph Laplacian matrices, whose eigenpairs are often interpreted as the frequencies and the Fourier basis vectors on a given graph. We point out, however, that such an interpretation is misleading unless the underlying graph is either an unweighted path or cycle. We then discuss our recent effort of constructing multiscale basis dictionaries on a graph, including the Hierarchical Graph Laplacian Eigenbasis Dictionary and the Generalized Haar-Walsh Wavelet Packet Dictionary, which are viewed as generalizations of the classical hierarchical block DCTs and the Haar-Walsh wavelet packets, respectively, to the graph setting. Finally, we demonstrate the usefulness of our dictionaries by using them to simultaneously segment and denoise 1-D noisy signals sampled on regular lattices, a problem where classical tools have difficulty.

  8. Absorption and adsorption chillers applied to air conditioning systems

    NASA Astrophysics Data System (ADS)

    Kuczyńska, Agnieszka; Szaflik, Władysław

    2010-07-01

    This work presents an application possibility of sorption refrigerators driven by low temperature fluid for air conditioning of buildings. Thermodynamic models were formulated and absorption LiBr-water chiller with 10 kW cooling power as well as adsorption chiller with silica gel bed were investigated. Both of them are using water for desorption process with temperature Tdes = 80 °C. Coefficient of performance (COP) for both cooling cycles was analyzed in the same conditions of the driving heat source, cooling water Tc = 25 °C and temperature in evaporator Tevap = 5 °C. In this study, the computer software EES was used to investigate the performance of absorption heat pump system and its behaviour in configuration with geothermal heat source.

  9. Automated document analysis system

    NASA Astrophysics Data System (ADS)

    Black, Jeffrey D.; Dietzel, Robert; Hartnett, David

    2002-08-01

    A software application has been developed to aid law enforcement and government intelligence gathering organizations in the translation and analysis of foreign language documents with potential intelligence content. The Automated Document Analysis System (ADAS) provides the capability to search (data or text mine) documents in English and the most commonly encountered foreign languages, including Arabic. Hardcopy documents are scanned by a high-speed scanner and are optical character recognized (OCR). Documents obtained in an electronic format bypass the OCR and are copied directly to a working directory. For translation and analysis, the script and the language of the documents are first determined. If the document is not in English, the document is machine translated to English. The documents are searched for keywords and key features in either the native language or translated English. The user can quickly review the document to determine if it has any intelligence content and whether detailed, verbatim human translation is required. The documents and document content are cataloged for potential future analysis. The system allows non-linguists to evaluate foreign language documents and allows for the quick analysis of a large quantity of documents. All document processing can be performed manually or automatically on a single document or a batch of documents.

  10. Network systems security analysis

    NASA Astrophysics Data System (ADS)

    Yilmaz, Ä.°smail

    2015-05-01

    Network Systems Security Analysis has utmost importance in today's world. Many companies, like banks which give priority to data management, test their own data security systems with "Penetration Tests" by time to time. In this context, companies must also test their own network/server systems and take precautions, as the data security draws attention. Based on this idea, the study cyber-attacks are researched throughoutly and Penetration Test technics are examined. With these information on, classification is made for the cyber-attacks and later network systems' security is tested systematically. After the testing period, all data is reported and filed for future reference. Consequently, it is found out that human beings are the weakest circle of the chain and simple mistakes may unintentionally cause huge problems. Thus, it is clear that some precautions must be taken to avoid such threats like updating the security software.

  11. A System Analysis Tool

    SciTech Connect

    CAMPBELL,PHILIP L.; ESPINOZA,JUAN

    2000-06-01

    In this paper we describe a tool for analyzing systems. The analysis is based on program slicing. It answers the following question for the software: if the value of a particular variable changes, what other variable values also change, and what is the path in between? program slicing was developed based on intra-procedure control and data flow. It has been expanded commercially to inter-procedure flow. However, we extend slicing to collections of programs and non-program entities, which we term multi-domain systems. The value of our tool is that an analyst can model the entirety of a system, not just the software, and we believe that this makes for a significant increase in power. We are building a prototype system.

  12. Speckle interferometry applied to asteroids and other solar system objects

    NASA Technical Reports Server (NTRS)

    Drummond, J. D.; Hege, E. K.

    1986-01-01

    Speckle interferometry is a high angular resolution technique that allows study of resolved asteroids. By following the changing size, shape, and orientation of minor planets, and with a few general assumptions (e.g., geometric scattering, triaxial ellipsoid figures, no albedo features), it is possible to directly measure an asteroid's true dimensions and the direction of its spin axis in one or two nights. A particular subset of triaxial ellipsoid figures are equilibrium shapes, and would imply that some asteroids are thoroughly fractured. Such shapes if they exist among the asteroids would allow a determination of bulk density since there is a unique relation among spin period, size, shape, and density. The discovery of even a single rubble pile, (just as the finding of even one binary asteroid by speckle interferometric techniques) would drastically alter the notion of asteroids as small solid planets. The Pluto/Charon system was studied to aid in improving the orbital elements necessary to predict the eclipse/occultation season currently in progress. Four asteroids were reduced to their size, shape, and pole direction: 433 Eros, 532 Herculina, 511 Davida, and 2 Pallas.

  13. Beyond Time out and Table Time: Today's Applied Behavior Analysis for Students with Autism

    ERIC Educational Resources Information Center

    Boutot, E. Amanda; Hume, Kara

    2012-01-01

    Recent mandates related to the implementation of evidence-based practices for individuals with autism spectrum disorder (ASD) require that autism professionals both understand and are able to implement practices based on the science of applied behavior analysis (ABA). The use of the term "applied behavior analysis" and its related concepts…

  14. Beyond Time Out and Table Time: Today's Applied Behavior Analysis for Students with Autism

    ERIC Educational Resources Information Center

    Boutot, E. Amanda; Hume, Kara

    2010-01-01

    Recent mandates related to the implementation of evidence-based practices for individuals with autism spectrum disorder (ASD) require that autism professionals both understand and are able to implement practices based on the science of applied behavior analysis (ABA). The use of the term "applied behavior analysis" and its related concepts…

  15. Applying axiomatic design to a medication distribution system

    NASA Astrophysics Data System (ADS)

    Raguini, Pepito B.

    As the need to minimize medication errors drives many medical facilities to come up with robust solutions to the most common error that affects patient's safety, these hospitals would be wise to put a concerted effort into finding methodologies that can facilitate an optimized medical distribution system. If the hospitals' upper management is looking for an optimization method that is an ideal fit, it is just as important that the right tool be selected for the application at hand. In the present work, we propose the application of Axiomatic Design (AD), which is a process that focuses on the generation and selection of functional requirements to meet the customer needs for product and/or process design. The appeal of the axiomatic approach is to provide both a formal design process and a set of technical coefficients for meeting the customer's needs. Thus, AD offers a strategy for the effective integration of people, design methods, design tools and design data. Therefore, we propose the AD methodology to medical applications with the main objective of allowing nurses the opportunity to provide cost effective delivery of medications to inpatients, thereby improving quality patient care. The AD methodology will be implemented through the use of focused stores, where medications can be readily stored and can be conveniently located near patients, as well as a mobile apparatus that can also store medications and is commonly used by hospitals, the medication cart. Moreover, a robust methodology called the focused store methodology will be introduced and developed for both the uncapacitated and capacitated case studies, which will set up an appropriate AD framework and design problem for a medication distribution case study.

  16. Systems thinking applied to safety during manual handling tasks in the transport and storage industry.

    PubMed

    Goode, Natassia; Salmon, Paul M; Lenné, Michael G; Hillard, Peter

    2014-07-01

    Injuries resulting from manual handling tasks represent an on-going problem for the transport and storage industry. This article describes an application of a systems theory-based approach, Rasmussen's (1997. Safety Science 27, 183), risk management framework, to the analysis of the factors influencing safety during manual handling activities in a freight handling organisation. Observations of manual handling activities, cognitive decision method interviews with workers (n=27) and interviews with managers (n=35) were used to gather information about three manual handling activities. Hierarchical task analysis and thematic analysis were used to identify potential risk factors and performance shaping factors across the levels of Rasmussen's framework. These different data sources were then integrated using Rasmussen's Accimap technique to provide an overall analysis of the factors influencing safety during manual handling activities in this context. The findings demonstrate how a systems theory-based approach can be applied to this domain, and suggest that policy-orientated, rather than worker-orientated, changes are required to prevent future manual handling injuries.

  17. Applying machine learning techniques to DNA sequence analysis. Progress report, February 14, 1991--February 13, 1992

    SciTech Connect

    Shavlik, J.W.

    1992-04-01

    We are developing a machine learning system that modifies existing knowledge about specific types of biological sequences. It does this by considering sample members and nonmembers of the sequence motif being learned. Using this information (which we call a ``domain theory``), our learning algorithm produces a more accurate representation of the knowledge needed to categorize future sequences. Specifically, the KBANN algorithm maps inference rules, such as consensus sequences, into a neural (connectionist) network. Neural network training techniques then use the training examples of refine these inference rules. We have been applying this approach to several problems in DNA sequence analysis and have also been extending the capabilities of our learning system along several dimensions.

  18. Distinguishing Pattern Formation Phenotypes: Applying Minkowski Functionals to Cell Biology Systems

    NASA Astrophysics Data System (ADS)

    Rericha, Erin; Guven, Can; Parent, Carole; Losert, Wolfgang

    2011-03-01

    Spatial Clustering of proteins within cells or cells themselves frequently occur in cell biology systems. However quantifying the underlying order and determining the regulators of these cluster patterns have proved difficult due to the inherent high noise levels in the systems. For instance the patterns formed by wild type and cyclic-AMP regulatory mutant Dictyostelium cells are visually distinctive, yet the large error bars in measurements of the fractal number, area, Euler number, eccentricity, and wavelength making it difficult to quantitatively distinguish between the patterns. We apply a spatial analysis technique based on Minkowski functionals and develop metrics which clearly separate wild type and mutant cell lines into distinct categories. Having such a metric facilitated the development of a computational model for cellular aggregation and its regulators. Supported by NIH-NGHS Nanotechnology (R01GM085574) and the Burroughs Wellcome Fund.

  19. Versatile microanalytical system with porous polypropylene capillary membrane for calibration gas generation and trace gaseous pollutants sampling applied to the analysis of formaldehyde, formic acid, acetic acid and ammonia in outdoor air.

    PubMed

    Coelho, Lúcia H G; Melchert, Wanessa R; Rocha, Flavio R; Rocha, Fábio R P; Gutz, Ivano G R

    2010-11-15

    The analytical determination of atmospheric pollutants still presents challenges due to the low-level concentrations (frequently in the μg m(-3) range) and their variations with sampling site and time. In this work, a capillary membrane diffusion scrubber (CMDS) was scaled down to match with capillary electrophoresis (CE), a quick separation technique that requires nothing more than some nanoliters of sample and, when combined with capacitively coupled contactless conductometric detection (C(4)D), is particularly favorable for ionic species that do not absorb in the UV-vis region, like the target analytes formaldehyde, formic acid, acetic acid and ammonium. The CMDS was coaxially assembled inside a PTFE tube and fed with acceptor phase (deionized water for species with a high Henry's constant such as formaldehyde and carboxylic acids, or acidic solution for ammonia sampling with equilibrium displacement to the non-volatile ammonium ion) at a low flow rate (8.3 nL s(-1)), while the sample was aspirated through the annular gap of the concentric tubes at 2.5 mL s(-1). A second unit, in all similar to the CMDS, was operated as a capillary membrane diffusion emitter (CMDE), generating a gas flow with know concentrations of ammonia for the evaluation of the CMDS. The fluids of the system were driven with inexpensive aquarium air pumps, and the collected samples were stored in vials cooled by a Peltier element. Complete protocols were developed for the analysis, in air, of NH(3), CH(3)COOH, HCOOH and, with a derivatization setup, CH(2)O, by associating the CMDS collection with the determination by CE-C(4)D. The ammonia concentrations obtained by electrophoresis were checked against the reference spectrophotometric method based on Berthelot's reaction. Sensitivity enhancements of this reference method were achieved by using a modified Berthelot reaction, solenoid micro-pumps for liquid propulsion and a long optical path cell based on a liquid core waveguide (LCW). All

  20. Systems analysis of bone.

    PubMed

    Jepsen, Karl J

    2009-01-01

    The genetic variants contributing to variability in skeletal traits has been well studied, and several hundred QTLs have been mapped and several genes contributing to trait variation have been identified. However, many questions remain unanswered. In particular, it is unclear whether variation in a single gene leads to alterations in function. Bone is a highly adaptive system and genetic variants affecting one trait are often accompanied by compensatory changes in other traits. The functional interactions among traits, which is known as phenotypic integration, has been observed in many biological systems, including bone. Phenotypic integration is a property of bone that is critically important for establishing a mechanically functional structure that is capable of supporting the forces imparted during daily activities. In this paper, bone is reviewed as a system and primarily in the context of functionality. A better understanding of the system properties of bone will lead to novel targets for future genetic analyses and the identification of genes that are directly responsible for regulating bone strength. This systems analysis has the added benefit of leaving a trail of valuable information about how the skeletal system works. This information will provide novel approaches to assessing skeletal health during growth and aging and for developing novel treatment strategies to reduce the morbidity and mortality associated with fragility fractures.

  1. Blind deconvolution applied to acoustical systems identification with supporting experimental results

    NASA Astrophysics Data System (ADS)

    Roan, Michael J.; Gramann, Mark R.; Erling, Josh G.; Sibul, Leon H.

    2003-10-01

    Many acoustical applications require the analysis of a signal that is corrupted by an unknown filtering function. Examples arise in the areas of noise or vibration control, room acoustics, structural vibration analysis, and speech processing. Here, the observed signal can be modeled as the convolution of the desired signal with an unknown system impulse response. Blind deconvolution refers to the process of learning the inverse of this unknown impulse response and applying it to the observed signal to remove the filtering effects. Unlike classical deconvolution, which requires prior knowledge of the impulse response, blind deconvolution requires only reasonable prior estimates of the input signal's statistics. The significant contribution of this work lies in experimental verification of a blind deconvolution algorithm in the context of acoustical system identification. Previous experimental work concerning blind deconvolution in acoustics has been minimal, as previous literature concerning blind deconvolution uses computer simulated data. This paper examines experiments involving three classical acoustic systems: driven pipe, driven pipe with open side branch, and driven pipe with Helmholtz resonator side branch. Experimental results confirm that the deconvolution algorithm learns these systems' inverse impulse responses, and that application of these learned inverses removes the effects of the filters.

  2. Computing and Systems Applied in Support of Coordinated Energy, Environmental, and Climate Planning

    EPA Science Inventory

    This talk focuses on how Dr. Loughlin is applying Computing and Systems models, tools and methods to more fully understand the linkages among energy systems, environmental quality, and climate change. Dr. Loughlin will highlight recent and ongoing research activities, including: ...

  3. Analysis of bilinear stochastic systems

    NASA Technical Reports Server (NTRS)

    Willsky, A. S.; Martin, D. N.; Marcus, S. I.

    1975-01-01

    Analysis of stochastic dynamical systems that involve multiplicative (bilinear) noise processes. After defining the systems of interest, consideration is given to the evolution of the moments of such systems, the question of stochastic stability, and estimation for bilinear stochastic systems. Both exact and approximate methods of analysis are introduced, and, in particular, the uses of Lie-theoretic concepts and harmonic analysis are discussed.

  4. Inclusive Elementary Classroom Teacher Knowledge of and Attitudes toward Applied Behavior Analysis and Autism Spectrum Disorder and Their Use of Applied Behavior Analysis

    ERIC Educational Resources Information Center

    McCormick, Jennifer A.

    2011-01-01

    The purpose of this study was to examine inclusive elementary teacher knowledge and attitude toward Autism Spectrum Disorder (ASD) and applied behavior analysis (ABA) and their use of ABA. Furthermore, this study examined if knowledge and attitude predicted use of ABA. A survey was developed and administered through a web-based program. Of the…

  5. Applied Time Domain Stability Margin Assessment for Nonlinear Time-Varying Systems

    NASA Technical Reports Server (NTRS)

    Kiefer, J. M.; Johnson, M. D.; Wall, J. H.; Dominguez, A.

    2016-01-01

    margins. At each time point, the system was linearized about the current operating point using Simulink's built-in solver. Each linearized system in time was evaluated for its rigid-body gain margin (high frequency gain margin), rigid-body phase margin, and aero gain margin (low frequency gain margin) for each control axis. Using the stability margins derived from the baseline linearization approach, the time domain derived stability margins were determined by executing time domain simulations in which axis-specific incremental gain and phase adjustments were made to the nominal system about the expected neutral stability point at specific flight times. The baseline stability margin time histories were used to shift the system gain to various values around the zero margin point such that a precise amount of expected gain margin was maintained throughout flight. When assessing the gain margins, the gain was applied starting at the time point under consideration, thereafter following the variation in the margin found in the linear analysis. When assessing the rigid-body phase margin, a constant time delay was applied to the system starting at the time point under consideration. If the baseline stability margins were correctly determined via the linear analysis, the time domain simulation results should contain unstable behavior at certain gain and phase values. Examples will be shown from repeated simulations with variable added gain and phase lag. Faithfulness of margins calculated from the linear analysis to the nonlinear system will be demonstrated.

  6. The Research Mission of Universities of Applied Sciences and the Future Configuration of Higher Education Systems in Europe

    ERIC Educational Resources Information Center

    Lepori, Benedetto; Kyvik, Svein

    2010-01-01

    This article presents a comparative analysis of the development of research in universities of applied sciences (UAS) in eight European countries and its implications for the configuration of the higher education system. The enhancement of research has mostly been seen as a case of academic drift where UAS attempt to become more similar to…

  7. Launch Vehicle Systems Analysis

    NASA Technical Reports Server (NTRS)

    Olds, John R.

    1999-01-01

    This report summaries the key accomplishments of Georgia Tech's Space Systems Design Laboratory (SSDL) under NASA Grant NAG8-1302 from NASA - Marshall Space Flight Center. The report consists of this summary white paper, copies of technical papers written under this grant, and several viewgraph-style presentations. During the course of this grant four main tasks were completed: (1)Simulated Combined-Cycle Rocket Engine Analysis Module (SCCREAM), a computer analysis tool for predicting the performance of various RBCC engine configurations; (2) Hyperion, a single stage to orbit vehicle capable of delivering 25,000 pound payloads to the International Space Station Orbit; (3) Bantam-X Support - a small payload mission; (4) International Trajectory Support for interplanetary human Mars missions.

  8. Reflections of the social environment in chimpanzee memory: applying rational analysis beyond humans

    PubMed Central

    Marewski, Julian N.; Schooler, Lael J.; Gilby, Ian C.

    2016-01-01

    In cognitive science, the rational analysis framework allows modelling of how physical and social environments impose information-processing demands onto cognitive systems. In humans, for example, past social contact among individuals predicts their future contact with linear and power functions. These features of the human environment constrain the optimal way to remember information and probably shape how memory records are retained and retrieved. We offer a primer on how biologists can apply rational analysis to study animal behaviour. Using chimpanzees (Pan troglodytes) as a case study, we modelled 19 years of observational data on their social contact patterns. Much like humans, the frequency of past encounters in chimpanzees linearly predicted future encounters, and the recency of past encounters predicted future encounters with a power function. Consistent with the rational analyses carried out for human memory, these findings suggest that chimpanzee memory performance should reflect those environmental regularities. In re-analysing existing chimpanzee memory data, we found that chimpanzee memory patterns mirrored their social contact patterns. Our findings hint that human and chimpanzee memory systems may have evolved to solve similar information-processing problems. Overall, rational analysis offers novel theoretical and methodological avenues for the comparative study of cognition. PMID:27853606

  9. Reflections of the social environment in chimpanzee memory: applying rational analysis beyond humans.

    PubMed

    Stevens, Jeffrey R; Marewski, Julian N; Schooler, Lael J; Gilby, Ian C

    2016-08-01

    In cognitive science, the rational analysis framework allows modelling of how physical and social environments impose information-processing demands onto cognitive systems. In humans, for example, past social contact among individuals predicts their future contact with linear and power functions. These features of the human environment constrain the optimal way to remember information and probably shape how memory records are retained and retrieved. We offer a primer on how biologists can apply rational analysis to study animal behaviour. Using chimpanzees (Pan troglodytes) as a case study, we modelled 19 years of observational data on their social contact patterns. Much like humans, the frequency of past encounters in chimpanzees linearly predicted future encounters, and the recency of past encounters predicted future encounters with a power function. Consistent with the rational analyses carried out for human memory, these findings suggest that chimpanzee memory performance should reflect those environmental regularities. In re-analysing existing chimpanzee memory data, we found that chimpanzee memory patterns mirrored their social contact patterns. Our findings hint that human and chimpanzee memory systems may have evolved to solve similar information-processing problems. Overall, rational analysis offers novel theoretical and methodological avenues for the comparative study of cognition.

  10. Constraints to applying systems thinking concepts in health systems: A regional perspective from surveying stakeholders in Eastern Mediterranean countries

    PubMed Central

    El-Jardali, Fadi; Adam, Taghreed; Ataya, Nour; Jamal, Diana; Jaafar, Maha

    2014-01-01

    Background: Systems Thinking (ST) has recently been promoted as an important approach to health systems strengthening. However, ST is not common practice, particularly in Low- and Middle-Income Countries (LMICs). This paper seeks to explore the barriers that may hinder its application in the Eastern Mediterranean Region (EMR) and possible strategies to mitigate them. Methods: A survey consisting of open-ended questions was conducted with a purposive sample of health policy-makers such as senior officials from the Ministry of Health (MoH), researchers, and other stakeholders such as civil society groups and professional associations from ten countries in the region. A total of 62 respondents participated in the study. Thematic analysis was conducted. Results: There was strong recognition of the relevance and usefulness of ST to health systems policy-making and research, although misconceptions about what ST means were also identified. Experience with applying ST was very limited. Approaches to designing health policies in the EMR were perceived as reactive and fragmented (66%). Commonly perceived constraints to application of ST were: a perceived notion of its costliness combined with lack of the necessary funding to operationalize it (53%), competing political interests and lack of government accountability (50%), lack of awareness about relevance and value (47%), limited capacity to apply it (45%), and difficulty in coordinating and managing stakeholders (39%). Conclusion: While several strategies have been proposed to mitigate most of these constraints, they emphasized the importance of political endorsement and adoption of ST at the leadership level, together with building the necessary capacity to apply it and apply the learning in research and practice. PMID:25489598

  11. Neutron activation analysis system

    DOEpatents

    Taylor, M.C.; Rhodes, J.R.

    1973-12-25

    A neutron activation analysis system for monitoring a generally fluid media, such as slurries, solutions, and fluidized powders, including two separate conduit loops for circulating fluid samples within the range of radiation sources and detectors is described. Associated with the first loop is a neutron source that emits s high flux of slow and thermal neutrons. The second loop employs a fast neutron source, the flux from which is substantially free of thermal neutrons. Adjacent to both loops are gamma counters for spectrographic determination of the fluid constituents. Other gsmma sources and detectors are arranged across a portion of each loop for deterMining the fluid density. (Official Gazette)

  12. KRON's Method Applied to the Study of Electromagnetic Interference Occurring in Aerospace Systems

    NASA Astrophysics Data System (ADS)

    Leman, S.; Reineix, A.; Hoeppe, F.; Poiré, Y.; Mahoudi, M.; Démoulin, B.; Üstüner, F.; Rodriquez, V. P.

    2012-05-01

    In this paper, spacecraft and aircraft mock-ups are used to simulate the performance of KRON based tools applied to the simulation of large EMC systems. These tools aim to assist engineers in the design phase of complex systems. This is done by effectively evaluating the EM disturbances between antennas, electronic equipment, and Portable Electronic Devices found in large systems. We use a topological analysis of the system to model independent sub-volumes such as antennas, cables, equipments, PED and cavity walls. Each of these sub- volumes is modelled by an appropriate method which can be based on, for example, analytical expressions, transmission line theory or other numerical tools such as the full wave FDFD method. This representation associated with the electrical tensorial method of G.KRON leads to reasonable simulation times (typically a few minutes) and accurate results. Because equivalent sub-models are built separately, the main originality of this method is that each sub- volume can be easily replaced by another one without rebuilding the entire system. Comparisons between measurements and simulations will be also presented.

  13. The Failure Analysis in Traction Power System

    NASA Astrophysics Data System (ADS)

    Kim, Hyungchul; Heo, Guk-bum; Lee, Hyungwoo; Kim, Dong Jin; Kim, Jin O.

    2008-10-01

    This paper presents a failure analysis of traction power systems. The electric railway consists of traction power systems, various vehicles, operating equipment, track, overhead line and electric equipment. It is a fundamental function of traction power systems that they supply customers with acceptable reliability and high quality power. Perhaps the most commonly used reliability assessment for railway systems has been the failure analysis of the traction signal system. The reliability assessment of traction power systems has also been an indispensable issue for reliability assessment. This paper deals with the classification of railway accidents caused by electrification problems, the estimation of failure rate in power equipments and failure analysis using fault trees. In study cases, the fault tree method for failure analysis is applied to railway substations in South Korea.

  14. DATE analysis: A general theory of biological change applied to microarray data.

    PubMed

    Rasnick, David

    2009-01-01

    In contrast to conventional data mining, which searches for specific subsets of genes (extensive variables) to correlate with specific phenotypes, DATE analysis correlates intensive state variables calculated from the same datasets. At the heart of DATE analysis are two biological equations of state not dependent on genetic pathways. This result distinguishes DATE analysis from other bioinformatics approaches. The dimensionless state variable F quantifies the relative overall cellular activity of test cells compared to well-chosen reference cells. The variable pi(i) is the fold-change in the expression of the ith gene of test cells relative to reference. It is the fraction phi of the genome undergoing differential expression-not the magnitude pi-that controls biological change. The state variable phi is equivalent to the control strength of metabolic control analysis. For tractability, DATE analysis assumes a linear system of enzyme-connected networks and exploits the small average contribution of each cellular component. This approach was validated by reproducible values of the state variables F, RNA index, and phi calculated from random subsets of transcript microarray data. Using published microarray data, F, RNA index, and phi were correlated with: (1) the blood-feeding cycle of the malaria parasite, (2) embryonic development of the fruit fly, (3) temperature adaptation of Killifish, (4) exponential growth of cultured S. pneumoniae, and (5) human cancers. DATE analysis was applied to aCGH data from the great apes. A good example of the power of DATE analysis is its application to genomically unstable cancers, which have been refractory to data mining strategies.

  15. Symmetry analysis for nonlinear time reversal methods applied to nonlinear acoustic imaging

    NASA Astrophysics Data System (ADS)

    Dos Santos, Serge; Chaline, Jennifer

    2015-10-01

    Using symmetry invariance, nonlinear Time Reversal (TR) and reciprocity properties, the classical NEWS methods are supplemented and improved by new excitations having the intrinsic property of enlarging frequency analysis bandwidth and time domain scales, with now both medical acoustics and electromagnetic applications. The analysis of invariant quantities is a well-known tool which is often used in nonlinear acoustics in order to simplify complex equations. Based on a fundamental physical principle known as symmetry analysis, this approach consists in finding judicious variables, intrinsically scale dependant, and able to describe all stages of behaviour on the same theoretical foundation. Based on previously published results within the nonlinear acoustic areas, some practical implementation will be proposed as a new way to define TR-NEWS based methods applied to NDT and medical bubble based non-destructive imaging. This paper tends to show how symmetry analysis can help us to define new methodologies and new experimental set-up involving modern signal processing tools. Some example of practical realizations will be proposed in the context of biomedical non-destructive imaging using Ultrasound Contrast Agents (ACUs) where symmetry and invariance properties allow us to define a microscopic scale-invariant experimental set-up describing intrinsic symmetries of the microscopic complex system.

  16. Applying Dynamical Systems Theory to Optimize Libration Point Orbit Stationkeeping Maneuvers for WIND

    NASA Technical Reports Server (NTRS)

    Brown, Jonathan M.; Petersen, Jeremy D.

    2014-01-01

    NASA's WIND mission has been operating in a large amplitude Lissajous orbit in the vicinity of the interior libration point of the Sun-Earth/Moon system since 2004. Regular stationkeeping maneuvers are required to maintain the orbit due to the instability around the collinear libration points. Historically these stationkeeping maneuvers have been performed by applying an incremental change in velocity, or (delta)v along the spacecraft-Sun vector as projected into the ecliptic plane. Previous studies have shown that the magnitude of libration point stationkeeping maneuvers can be minimized by applying the (delta)v in the direction of the local stable manifold found using dynamical systems theory. This paper presents the analysis of this new maneuver strategy which shows that the magnitude of stationkeeping maneuvers can be decreased by 5 to 25 percent, depending on the location in the orbit where the maneuver is performed. The implementation of the optimized maneuver method into operations is discussed and results are presented for the first two optimized stationkeeping maneuvers executed by WIND.

  17. System of systems modeling and analysis.

    SciTech Connect

    Campbell, James E.; Anderson, Dennis James; Longsine, Dennis E.; Shirah, Donald N.

    2005-01-01

    This report documents the results of an LDRD program entitled 'System of Systems Modeling and Analysis' that was conducted during FY 2003 and FY 2004. Systems that themselves consist of multiple systems (referred to here as System of Systems or SoS) introduce a level of complexity to systems performance analysis and optimization that is not readily addressable by existing capabilities. The objective of the 'System of Systems Modeling and Analysis' project was to develop an integrated modeling and simulation environment that addresses the complex SoS modeling and analysis needs. The approach to meeting this objective involved two key efforts. First, a static analysis approach, called state modeling, has been developed that is useful for analyzing the average performance of systems over defined use conditions. The state modeling capability supports analysis and optimization of multiple systems and multiple performance measures or measures of effectiveness. The second effort involves time simulation which represents every system in the simulation using an encapsulated state model (State Model Object or SMO). The time simulation can analyze any number of systems including cross-platform dependencies and a detailed treatment of the logistics required to support the systems in a defined mission.

  18. Applying Transactional Analysis and Personality Assessment to Improve Patient Counseling and Communication Skills

    PubMed Central

    Lawrence, Lesa

    2007-01-01

    Objective To teach pharmacy students how to apply transactional analysis and personality assessment to patient counseling to improve communication. Design A lecture series for a required pharmacy communications class was developed to teach pharmacy students how to apply transactional analysis and personality assessment to patient counseling. Students were asked to apply these techniques and to report their experiences. A personality self-assessment was also conducted. Assessment After attending the lecture series, students were able to apply the techniques and demonstrated an understanding of the psychological factors that may affect patient communication, an appreciation for the diversity created by different personality types, the ability to engage patients based on adult-to-adult interaction cues, and the ability to adapt the interactive patient counseling model to different personality traits. Conclusion Students gained a greater awareness of transactional analysis and personality assessment by applying these concepts. This understanding will help students communicate more effectively with patients. PMID:17786269

  19. Quantitative Systems Pharmacology Approaches Applied to Microphysiological Systems (MPS): Data Interpretation and Multi-MPS Integration

    PubMed Central

    Yu, J; Cilfone, NA; Large, EM; Sarkar, U; Wishnok, JS; Tannenbaum, SR; Hughes, DJ; Lauffenburger, DA; Griffith, LG; Stokes, CL; Cirit, M

    2015-01-01

    Our goal in developing Microphysiological Systems (MPS) technology is to provide an improved approach for more predictive preclinical drug discovery via a highly integrated experimental/computational paradigm. Success will require quantitative characterization of MPSs and mechanistic analysis of experimental findings sufficient to translate resulting insights from in vitro to in vivo. We describe herein a systems pharmacology approach to MPS development and utilization that incorporates more mechanistic detail than traditional pharmacokinetic/pharmacodynamic (PK/PD) models. A series of studies illustrates diverse facets of our approach. First, we demonstrate two case studies: a PK data analysis and an inflammation response––focused on a single MPS, the liver/immune MPS. Building on the single MPS modeling, a theoretical investigation of a four-MPS interactome then provides a quantitative way to consider several pharmacological concepts such as absorption, distribution, metabolism, and excretion in the design of multi-MPS interactome operation and experiments. PMID:26535159

  20. Applying gap analysis and a comparison index to evaluate protected areas in Thailand.

    PubMed

    Trisurat, Yongyut

    2007-02-01

    Protected areas in Thailand were first established 40 years ago. The total area of existing protected areas covers 18.2% of the country's land area and the Class 1 Watershed, another form of protection, encompasses 18.1%. The government of Thailand intends to increase protected area systems to 25% of the country in 2006 and 30% in 2016. There are always questions arising about how much is enough protected areas to effectively protect biodiversity. The objective of this article is to assess the representation of ecosystems in the protected area network. This article also recommends which underrepresented ecosystems should be added to fill the gaps in representativeness. The research applies a gap analysis and a comparison index to assess the representation of ecosystems within the protected area network. The spatial analyses were applied to measure three aspects of representativeness, namely forest type, altitude, and natural land system. The analyses indicate that the existing protected area system covers 24.4% of the country's land area, nearly meeting the 25% target proposed by the National Forest Policy; and 83.8% of these areas are under forest cover. Most protected areas are situated in high altitudes, where biological diversity is less than in lowlands. Mangrove forest and riparian floodplain are extremely underrepresented in the existing system. Peat swamp forest, dry dipterocarp forest, and beach forest are relatively well represented. In addition, these five ecosystems are threatened by human pressures and natural disasters; therefore, they should be targeted as high priorities for the selection of new reserves. Future research should incorporate aquatic and marine ecosystems, as well as animal distributions, which were not included in this research due to data unavailabilities.

  1. A method for work modeling at complex systems: towards applying information systems in family health care units.

    PubMed

    Jatobá, Alessandro; de Carvalho, Paulo Victor R; da Cunha, Amauri Marques

    2012-01-01

    Work in organizations requires a minimum level of consensus on the understanding of the practices performed. To adopt technological devices to support the activities in environments where work is complex, characterized by the interdependence among a large number of variables, understanding about how work is done not only takes an even greater importance, but also becomes a more difficult task. Therefore, this study aims to present a method for modeling of work in complex systems, which allows improving the knowledge about the way activities are performed where these activities do not simply happen by performing procedures. Uniting techniques of Cognitive Task Analysis with the concept of Work Process, this work seeks to provide a method capable of providing a detailed and accurate vision of how people perform their tasks, in order to apply information systems for supporting work in organizations.

  2. Research in progress in applied mathematics, numerical analysis, and computer science

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Research conducted at the Institute in Science and Engineering in applied mathematics, numerical analysis, and computer science is summarized. The Institute conducts unclassified basic research in applied mathematics in order to extend and improve problem solving capabilities in science and engineering, particularly in aeronautics and space.

  3. Applied behavior analysis: understanding and changing behavior in the community-a representative review.

    PubMed

    Luyben, Paul D

    2009-01-01

    Applied behavior analysis, a psychological discipline, has been characterized as the science of behavior change (Chance, 2006). Research in applied behavior analysis has been published for approximately 40 years since the initial publication of the Journal of Applied Behavior Analysis in 1968. The field now encompasses a wide range of human behavior. Although much of the published research centers on problem behaviors that occur in schools and among people with disabilities, a substantial body of knowledge has emerged in community settings. This article provides a review of the behavioral community research published in the Journal of Applied Behavior Analysis as representative of this work, including research in the areas of home and family, health, safety, community involvement and the environment, recreation and sports, crime and delinquency, and organizations. In the interest of space, research in schools and with people with disabilities has been excluded from this review.

  4. Systems Engineering Techniques Applied to the BepiColombo MPO Science Ground Segment Design

    NASA Astrophysics Data System (ADS)

    de la Fluente, Sara; Perez-Lopez, Fernando; Casale, Mauro

    2013-08-01

    BepiColombo is an interdisciplinary mission to Mercury scheduled for launch in 2015, arriving at Mercury in 2021. It is a joint mission between ESA and JAXA consisting of 2 complementary spacecraft, the Mercury Planetary Orbiter (MPO) and the Mercury Magnetospheric Orbiter (MMO). BepiColombo MPO scientific payload comprises 11 instrument packages comprising 17 experiments that will investigate the Mercury planet interior, surface composition and morphology, the intrinsic magnetic field and the composition of the exosphere and the coupling between all of these fields. Several Systems engineering techniques for requirements capture, verification, modelling and analysis, etc have been applied in the design of the Science Ground Segment, located at the European Space Astronomy Centre (ESAC) in Madrid, Spain.

  5. System Identification Applied to Dynamic CFD Simulation and Wind Tunnel Data

    NASA Technical Reports Server (NTRS)

    Murphy, Patrick C.; Klein, Vladislav; Frink, Neal T.; Vicroy, Dan D.

    2011-01-01

    Demanding aerodynamic modeling requirements for military and civilian aircraft have provided impetus for researchers to improve computational and experimental techniques. Model validation is a key component for these research endeavors so this study is an initial effort to extend conventional time history comparisons by comparing model parameter estimates and their standard errors using system identification methods. An aerodynamic model of an aircraft performing one-degree-of-freedom roll oscillatory motion about its body axes is developed. The model includes linear aerodynamics and deficiency function parameters characterizing an unsteady effect. For estimation of unknown parameters two techniques, harmonic analysis and two-step linear regression, were applied to roll-oscillatory wind tunnel data and to computational fluid dynamics (CFD) simulated data. The model used for this study is a highly swept wing unmanned aerial combat vehicle. Differences in response prediction, parameters estimates, and standard errors are compared and discussed

  6. An introductory review of parallel independent component analysis (p-ICA) and a guide to applying p-ICA to genetic data and imaging phenotypes to identify disease-associated biological pathways and systems in common complex disorders

    PubMed Central

    Pearlson, Godfrey D.; Liu, Jingyu; Calhoun, Vince D.

    2015-01-01

    Complex inherited phenotypes, including those for many common medical and psychiatric diseases, are most likely underpinned by multiple genes contributing to interlocking molecular biological processes, along with environmental factors (Owen et al., 2010). Despite this, genotyping strategies for complex, inherited, disease-related phenotypes mostly employ univariate analyses, e.g., genome wide association. Such procedures most often identify isolated risk-related SNPs or loci, not the underlying biological pathways necessary to help guide the development of novel treatment approaches. This article focuses on the multivariate analysis strategy of parallel (i.e., simultaneous combination of SNP and neuroimage information) independent component analysis (p-ICA), which typically yields large clusters of functionally related SNPs statistically correlated with phenotype components, whose overall molecular biologic relevance is inferred subsequently using annotation software suites. Because this is a novel approach, whose details are relatively new to the field we summarize its underlying principles and address conceptual questions regarding interpretation of resulting data and provide practical illustrations of the method. PMID:26442095

  7. Risk analysis for confined space entries: Critical analysis of four tools applied to three risk scenarios.

    PubMed

    Burlet-Vienney, Damien; Chinniah, Yuvin; Bahloul, Ali; Roberge, Brigitte

    2016-01-01

    Investigation reports of fatal confined space accidents nearly always point to a problem of identifying or underestimating risks. This paper compares 4 different risk analysis tools developed for confined spaces by applying them to 3 hazardous scenarios. The tools were namely 1. a checklist without risk estimation (Tool A), 2. a checklist with a risk scale (Tool B), 3. a risk calculation without a formal hazard identification stage (Tool C), and 4. a questionnaire followed by a risk matrix (Tool D). Each tool's structure and practical application were studied. Tools A and B gave crude results comparable to those of more analytic tools in less time. Their main limitations were lack of contextual information for the identified hazards and greater dependency on the user's expertise and ability to tackle hazards of different nature. Tools C and D utilized more systematic approaches than tools A and B by supporting risk reduction based on the description of the risk factors. Tool D is distinctive because of 1. its comprehensive structure with respect to the steps suggested in risk management, 2. its dynamic approach to hazard identification, and 3. its use of data resulting from the risk analysis.

  8. Integrated fluorescence analysis system

    DOEpatents

    Buican, Tudor N.; Yoshida, Thomas M.

    1992-01-01

    An integrated fluorescence analysis system enables a component part of a sample to be virtually sorted within a sample volume after a spectrum of the component part has been identified from a fluorescence spectrum of the entire sample in a flow cytometer. Birefringent optics enables the entire spectrum to be resolved into a set of numbers representing the intensity of spectral components of the spectrum. One or more spectral components are selected to program a scanning laser microscope, preferably a confocal microscope, whereby the spectrum from individual pixels or voxels in the sample can be compared. Individual pixels or voxels containing the selected spectral components are identified and an image may be formed to show the morphology of the sample with respect to only those components having the selected spectral components. There is no need for any physical sorting of the sample components to obtain the morphological information.

  9. Experimental Research on Micro-nozzle Applied on Micro-propulsion Systems based on MEMS

    NASA Astrophysics Data System (ADS)

    Bao-jun, Zhang; Xing-chen, Li; Yi-yong, Huang; Xiang-ming, Xu

    2017-03-01

    In order to study the influence of the structural parameters of micro thruster applied in micro satellite attitude adjustment and orbital maneuver on its propulsion performance, this paper considers the factors influencing the performance of the thruster, and utilizes the orthogonal test design to obtain nine groups of micro-nozzles with different structural parameters. We processed this series of micro nozzles through MEMS (Micro-Electro-Mechanical Systems) technology. The micro-nozzles are made of single crystal silicon and glass through the anode bonding, and the electric heating wire is creatively processed through MEMS in the thrust chamber to improve the performance of the micro thruster. Experiments were carried out in a vacuum chamber. Finally, we analyse the experimental results by analysis of variance and analysis of range. The experimental results show that the performance of the micro nozzle is optimal when the semi-shrinking angle is 30 degrees, the semi-expansion angle is 15 degrees and the area ratio is 6.22. Meantime, the experiment verifies that it is feasible to improve the propulsive performance of micro-propulsion system through electronic heater strip.

  10. An Error Analysis for the Finite Element Method Applied to Convection Diffusion Problems.

    DTIC Science & Technology

    1981-03-01

    D TFhG-]NOLOGY k 4b 00 \\" ) ’b Technical Note BN-962 AN ERROR ANALYSIS FOR THE FINITE ELEMENT METHOD APPLIED TO CONVECTION DIFFUSION PROBLEM by I...Babu~ka and W. G. Szym’czak March 1981 V.. UNVI I Of- ’i -S AN ERROR ANALYSIS FOR THE FINITE ELEMENT METHOD P. - 0 w APPLIED TO CONVECTION DIFFUSION ...AOAO98 895 MARYLAND UNIVYCOLLEGE PARK INST FOR PHYSICAL SCIENCE--ETC F/G 12/I AN ERROR ANALYIS FOR THE FINITE ELEMENT METHOD APPLIED TO CONV..ETC (U

  11. An improved leaping detector for flow analysis applied to iron speciation in drugs

    PubMed Central

    Santos, Sérgio R. B.; Araújo, Mário C. U.; Honorato, Ricardo S.; Zagatto, Elias A. G.; Lima, José F. C.; Lapa, Rui A. S.

    2000-01-01

    A low inner volume (ca. 64 ml) probe was built up in an injector-commutator in order to behave as a photometric leaping detector in flow analysis. It comprises a bicolour light-emitting diode (BLED), as a source of pulsed radiation in the red and green visible region, and two phototransistors as transducers. Sample injection, detector relocation, analytical signal recording, data treatment and definition of the spectral working range were computer-controlled. The feasibility of the system was initially demonstrated in the flow-injection speciation of iron, and the overall standard deviation of results was estimated as ± 1.6 and ± 1.4% for 1.6–4.0 mg l−1 Fe(II) or total iron after eightfold processing of synthetic samples. The system was further applied to drug analysis: the mean deviations of results for typical samples were estimated as ± 5.2 and ± 3.3%, and the relative standard deviation as ± 1.6 and ± 1.3% for Fe(II) and total iron, respectively. Results were compared with those obtained by a conventional spectrophotometric procedure and no statistic differences at the 95% confidence level were found. In relation to an earlier system with multi-site detection, the proposed system is more stable, presenting low drift with a relative standard deviation of 0.026% and 0.039% for measurements (n=120 during 4 h of observation) with green and red emission. It is also faster with a sampling rate of 133 h−1 and carryover problems are not found. The possibility of compensating the Schlieren noise by dual-wavelength spectrophotometry is discussed. PMID:18924860

  12. Multimodel Bayesian analysis of data-worth applied to unsaturated fractured tuffs

    NASA Astrophysics Data System (ADS)

    Lu, Dan; Ye, Ming; Neuman, Shlomo P.; Xue, Liang

    2012-01-01

    To manage water resource and environmental systems effectively requires suitable data. The worth of collecting such data depends on their potential benefit and cost, including the expected cost (risk) of failing to take an appropriate decision. Evaluating this risk calls for a probabilistic approach to data-worth assessment. Recently we [39] developed a multimodel approach to optimum value-of-information or data-worth analysis based on model averaging within a maximum likelihood Bayesian framework. Adopting a two-dimensional synthetic example, we implemented our approach using Monte Carlo (MC) simulations with and without lead order approximations, finding that the former approach was almost equally accurate but computationally more efficient. Here we apply our methodology to pneumatic permeability data from vertical and inclined boreholes drilled into unsaturated fractured tuff near Superior, Arizona. In an attempt to improve computational efficiency, we introduce three new approximations that require less computational effort and compare results with those obtained by the original Monte Carlo method. The first approximation disregards uncertainty in model parameter estimates, the second does so for estimates of potential new data, and the third disregards both uncertainties. We find that only the first approximation yields reliable quantitative assessments of reductions in predictive uncertainty brought about by the collection of new data. We conclude that, whereas parameter uncertainty may sometimes be disregarded for purposes of analyzing data worth, the same does not generally apply to uncertainty in estimates of potential new data.

  13. Applied Systemic Theory and Educational Psychology: Can the Twain Ever Meet?

    ERIC Educational Resources Information Center

    Pellegrini, Dario W.

    2009-01-01

    This article reflects on the potential benefits of applying systemic theory to the work of educational psychologists (EPs). It reviews developments in systemic thinking over time, and discusses the differences between more directive "first order" versus collaborative "second order" approaches. It considers systemic theories and…

  14. Applying Systems Engineering to Implement an Evidence-based Intervention at a Community Health Center

    PubMed Central

    Tu, Shin-Ping; Feng, Sherry; Storch, Richard; Yip, Mei-Po; Sohng, HeeYon; Fu, Mingang; Chun, Alan

    2013-01-01

    Summary Impressive results in patient care and cost reduction have increased the demand for systems-engineering methodologies in large health care systems. This Report from the Field describes the feasibility of applying systems-engineering techniques at a community health center currently lacking the dedicated expertise and resources to perform these activities. PMID:23698657

  15. Microfabricated Genomic Analysis System

    NASA Technical Reports Server (NTRS)

    Gonda, Steve; Elms, Rene

    2005-01-01

    Genetic sequencing and many genetic tests and assays require electrophoretic separation of DNA. In this technique, DNA fragments are separated by size as they migrate through a sieving gel under the influence of an applied electric field. In order to conduct these analyses on-orbit, it is essential to acquire the capability to efficiently perform electrophoresis in a microgravity environment. Conventional bench top electrophoresis equipment is large and cumbersome and does not lead itself to on-orbit utilization. Much of the previous research regarding on-orbit electrophoresis involved altering conventional electrophoresis equipment for bioprocessing, purification, and/or separation technology applications. A new and more efficient approach to on-orbit electrophoresis is the use of a microfabricated electrophoresis platform. These platforms are much smaller, less expensive to produce and operate, use less power, require smaller sample sizes (nanoliters), and achieve separation in a much shorter distance (a few centimeters instead of 10 s or 100 s of centimeters.) In contrast to previous applications, this platform would be utilized as an analytical tool for life science/medical research, environmental monitoring, and medical diagnoses. Identification of infectious agents as well as radiation related damage are significant to NASA s efforts to maintain, study, and monitor crew health during and in support of near-Earth and interplanetary missions. The capability to perform genetic assays on-orbit is imperative to conduct relevant and insightful biological and medical research, as well as continuing NASA s search for life elsewhere. This technology would provide an essential analytical tool for research conducted in a microgravity environment (Shuttle, ISS, long duration/interplanetary missions.) In addition, this technology could serve as a critical and invaluable component of a biosentinel system to monitor space environment genotoxic insults to include radiation.

  16. PRN 87-1: Label Improvement Program for Pesticides Applied through Irrigation Systems (Chemigation)

    EPA Pesticide Factsheets

    This Notice requires registrants of pesticide products registered under FIFRA and applied through irrigation systems to revise the labeling for such products to include additional use directions and other statements described in this Notice.

  17. Applied Behavior Analysis: Its Impact on the Treatment of Mentally Retarded Emotionally Disturbed People.

    ERIC Educational Resources Information Center

    Matson, Johnny L.; Coe, David A.

    1992-01-01

    This article reviews applications of the applied behavior analysis ideas of B. F. Skinner and others to persons with both mental retardation and emotional disturbance. The review examines implications of behavior analysis for operant conditioning and radical behaviorism, schedules of reinforcement, and emotion and mental illness. (DB)

  18. Sociosexuality Education for Persons with Autism Spectrum Disorders Using Principles of Applied Behavior Analysis

    ERIC Educational Resources Information Center

    Wolfe, Pamela S.; Condo, Bethany; Hardaway, Emily

    2009-01-01

    Applied behavior analysis (ABA) has emerged as one of the most effective empirically based strategies for instructing individuals with autism spectrum disorders (ASD). Four ABA-based strategies that have been found effective are video modeling, visual strategies, social script fading, and task analysis. Individuals with ASD often struggle with…

  19. Applied Behaviour Analysis and Intellectual Disability: A Long-Term Relationship?

    ERIC Educational Resources Information Center

    Remington, Bob

    1998-01-01

    This evaluative review describes the history of applied behavior analysis in the area of developmental disability and its strengths and weaknesses. Emphasis is placed on the fact that behavior analysis can continue to provide valuable insights into the education and treatment of people with mental retardation. (Author/CR)

  20. Improving Skill Development: An Exploratory Study Comparing a Philosophical and an Applied Ethical Analysis Technique

    ERIC Educational Resources Information Center

    Al-Saggaf, Yeslam; Burmeister, Oliver K.

    2012-01-01

    This exploratory study compares and contrasts two types of critical thinking techniques; one is a philosophical and the other an applied ethical analysis technique. The two techniques analyse an ethically challenging situation involving ICT that a recent media article raised to demonstrate their ability to develop the ethical analysis skills of…

  1. An Objective Comparison of Applied Behavior Analysis and Organizational Behavior Management Research

    ERIC Educational Resources Information Center

    Culig, Kathryn M.; Dickinson, Alyce M.; McGee, Heather M.; Austin, John

    2005-01-01

    This paper presents an objective review, analysis, and comparison of empirical studies targeting the behavior of adults published in Journal of Applied Behavior Analysis (JABA) and Journal of Organizational Behavior Management (JOBM) between 1997 and 2001. The purpose of the comparisons was to identify similarities and differences with respect to…

  2. Integrated tools for control-system analysis

    NASA Technical Reports Server (NTRS)

    Ostroff, Aaron J.; Proffitt, Melissa S.; Clark, David R.

    1989-01-01

    The basic functions embedded within a user friendly software package (MATRIXx) are used to provide a high level systems approach to the analysis of linear control systems. Various control system analysis configurations are assembled automatically to minimize the amount of work by the user. Interactive decision making is incorporated via menu options and at selected points, such as in the plotting section, by inputting data. There are five evaluations such as the singular value robustness test, singular value loop transfer frequency response, Bode frequency response, steady-state covariance analysis, and closed-loop eigenvalues. Another section describes time response simulations. A time response for random white noise disturbance is available. The configurations and key equations used for each type of analysis, the restrictions that apply, the type of data required, and an example problem are described. One approach for integrating the design and analysis tools is also presented.

  3. A Cost-Benefit Analysis Applied to Example Proposals for Army Training and Education Research

    DTIC Science & Technology

    2008-02-01

    ARI Research Note 2008-01 A Cost-Benefit Analysis Applied to Example Proposals for Army Training and Education Research John E. Morrison, J. Dexter...2008 4. TITLE AND SUBTITLE 5a, CONTRACT OR GRANT NUMBER A Cost-Benefit Analysis Applied to Example Proposalsfor Army DASWO1 -04-C-0003 and W74V8H-05-C...elements of the current analysis were 21 proposed R&D efforts derived from concepts discussed in the workshop. Total costs were calculated in two ways: (1

  4. Thermal Analysis of Calorimetric Systems

    NASA Astrophysics Data System (ADS)

    D'Aulerio, L.; Violante, V.; Castagna, E.; Fiore, R.; Capobianco, L.; Del Prete, Pr.; Tanzella, F.; McKubre, M.

    Calorimetric analysis has been carried out for both electrochemical and gas loading experiment. A finite element modeling for steady state and transient gave a satisfactory agreement with the experimental results. For electrochemical cells modeling was applied for isoperibolic and flow calorimeters with the main goal to optimize the system. For high-temperature gas loading experiments the modeling was applied to translate the temperature field (steady state and transient three-dimensional analysis), then, in such a case calculations allowed to perform the calorimetry. This experiment was a replication of the MATRIX experiment performed at SRI by some of the authors.1,2 A correlation between 4He production and excess of power during gas loading of deuterium in palladium was observed. Excess of power was estimated by means of the temperature measurements and by comparing experimental data with both the calibration data and the modeling results. Also the effect of the room temperature evolution was considered in the mathematical model of the experiment. 4He tights stainless steel cell have been filled first with a Pd-based catalyst then loaded with deuterium or hydrogen (blank). After filling cells with gas we observed a different thermal behavior of the cells C1 and C2 containing deuterium, compared to the cell C4 containing hydrogen. The temperature increasing in cells C1 and C2 was estimated to be produced by an additional power source of 0.1 W. The measured excess of helium was consistent with expected value obtained by assuming that the excess of energy was produced by a D+D reaction giving 4He+heat (24 MeV). The slope of the temperature increasing was larger in cells C1 and C2, and after achieving a stationary condition for the system the temperature of cells C1 and C2 increased again. During the thermal effect an analysis of the gas was done for the cells C1 and C2. An increasing of the helium content was revealed for both the cells. The He concentration

  5. Applications Of Modern Systems Analysis

    NASA Technical Reports Server (NTRS)

    Wagner, Robert C.; Biernacki, John V.; Bodi, Robert F.; Juhasz, John E.

    1994-01-01

    cour papers discuss applications of interdisciplinary methodologies incorporating elaborate mathematical models and computer programs as paradigms of modern systems analysis. Unifying concept underlying presentations is need for more sophisticated methods of systems analysis to manage increasingly complex engineering and socioeconomic systems.

  6. Spherical harmonic decomposition applied to spatial-temporal analysis of human high-density electroencephalogram

    NASA Astrophysics Data System (ADS)

    Wingeier, B. M.; Nunez, P. L.; Silberstein, R. B.

    2001-11-01

    We demonstrate an application of spherical harmonic decomposition to the analysis of the human electroencephalogram (EEG). We implement two methods and discuss issues specific to the analysis of hemispherical, irregularly sampled data. Spatial sampling requirements and performance of the methods are quantified using simulated data. The analysis is applied to experimental EEG data, confirming earlier reports of an approximate frequency-wave-number relationship in some bands.

  7. Selection of clinical features for pattern recognition applied to gait analysis.

    PubMed

    Altilio, Rosa; Paoloni, Marco; Panella, Massimo

    2017-04-01

    This paper deals with the opportunity of extracting useful information from medical data retrieved directly from a stereophotogrammetric system applied to gait analysis. A feature selection method to exhaustively evaluate all the possible combinations of the gait parameters is presented, in order to find the best subset able to classify among diseased and healthy subjects. This procedure will be used for estimating the performance of widely used classification algorithms, whose performance has been ascertained in many real-world problems with respect to well-known classification benchmarks, both in terms of number of selected features and classification accuracy. Precisely, support vector machine, Naive Bayes and K nearest neighbor classifiers can obtain the lowest classification error, with an accuracy greater than 97 %. For the considered classification problem, the whole set of features will be proved to be redundant and it can be significantly pruned. Namely, groups of 3 or 5 features only are able to preserve high accuracy when the aim is to check the anomaly of a gait. The step length and the swing speed are the most informative features for the gait analysis, but also cadence and stride may add useful information for the movement evaluation.

  8. Quantum analysis applied to thermo field dynamics on dissipative systems

    SciTech Connect

    Hashizume, Yoichiro; Okamura, Soichiro; Suzuki, Masuo

    2015-03-10

    Thermo field dynamics is one of formulations useful to treat statistical mechanics in the scheme of field theory. In the present study, we discuss dissipative thermo field dynamics of quantum damped harmonic oscillators. To treat the effective renormalization of quantum dissipation, we use the Suzuki-Takano approximation. Finally, we derive a dissipative von Neumann equation in the Lindbrad form. In the present treatment, we can easily obtain the initial damping shown previously by Kubo.

  9. Evaluation of bitterness in white wine applying descriptive analysis, time-intensity analysis, and temporal dominance of sensations analysis.

    PubMed

    Sokolowsky, Martina; Fischer, Ulrich

    2012-06-30

    Bitterness in wine, especially in white wine, is a complex and sensitive topic as it is a persistent sensation with negative connotation by consumers. However, the molecular base for bitter taste in white wines is still widely unknown yet. At the same time studies dealing with bitterness have to cope with the temporal dynamics of bitter perception. The most common method to describe bitter taste is the static measurement amongst other attributes during a descriptive analysis. A less frequently applied method, the time-intensity analysis, evaluates the temporal gustatory changes focusing on bitterness alone. The most recently developed multidimensional approach of the temporal dominance of sensations method reveals the temporal dominance of bitter taste in relation to other attributes. In order to compare the results comprised with these different sensory methodologies, 13 commercial white wines were evaluated by the same panel. To facilitate a statistical comparison, parameters were extracted from bitterness curves obtained from time-intensity and temporal dominance of sensations analysis and were compared to bitter intensity as well as bitter persistency based on descriptive analysis. Analysis of variance differentiated significantly the wines regarding all measured bitterness parameters obtained from the three sensory techniques. Comparing the information of all sensory parameters by multiple factor analysis and correlation, each technique provided additional valuable information regarding the complex bitter perception in white wine.

  10. Quasi-dynamic Material Flow Analysis applied to the Austrian Phosphorus cycle

    NASA Astrophysics Data System (ADS)

    Zoboli, Ottavia; Rechberger, Helmut

    2013-04-01

    Phosphorus (P) is one of the key elements that sustain life on earth and that allow achieving the current high levels of food production worldwide. It is a non-renewable resource, without any existing substitute. Because of its current dissipative use by mankind and to its very slow geochemical cycle, this resource is rapidly depleting and it is strongly connected to the problem of ensuring food security. Moreover P is also associated to important environmental problems. Its extraction often generates hazardous wastes, while its accumulation in water bodies can lead to eutrophication, with consequent severe ecological damages. It is therefore necessary to analyze and understand in detail the system of P, in regard to its use and management, to identify the processes that should be targeted in order to reduce the overall consumption of this resource. This work aims at establishing a generic quasi-dynamic model, which describes the Austrian P-budget and which allows investigating the trends of P use in the past, but also selected future scenarios. Given the importance of P throughout the whole anthropogenic metabolism, the model is based on a comprehensive system that encompasses several economic sectors, from agriculture and animal husbandry to industry, consumption and waste and wastewater treatment. Furthermore it includes the hydrosphere, to assess the losses of P into water bodies, due to the importance of eutrophication problems. The methodology applied is Material Flow Analysis (MFA), which is a systemic approach to assess and balance the stocks and flows of a material within a system defined in space and time. Moreover the model is integrated in the software STAN, a freeware tailor-made for MFA. Particular attention is paid to the characteristics and the quality of the data, in order to include data uncertainty and error propagation in the dynamic balance.

  11. Interactive Image Analysis System Design,

    DTIC Science & Technology

    1982-12-01

    This report describes a design for an interactive image analysis system (IIAS), which implements terrain data extraction techniques. The design... analysis system. Additionally, the system is fully capable of supporting many generic types of image analysis and data processing, and is modularly...employs commercially available, state of the art minicomputers and image display devices with proven software to achieve a cost effective, reliable image

  12. Preliminary evaluation of an ATR system applied to robotic tank inspection

    SciTech Connect

    Conner, C.; Lassahn, G.; Nash, T.; Briebenow, B.

    1994-12-31

    A brief evaluation of the capabilities of an automatic target recognition system as applied to processing digitized data from robotic inspection of radioactive liquid waste storage tanks has been performed. The intent of this application is to use the target recognition system as a fast data screening tool to flag scenes that might indicate tank defects.

  13. Photometric analysis of the system Kepler-1

    NASA Astrophysics Data System (ADS)

    Budding, E.; Rhodes, M. D.; Püsküllü, Ç.; Ji, Y.; Erdem, A.; Banks, T.

    2016-10-01

    We have applied the close binary system analysis program WinFitter to an intensive study of Kepler-1 (= TrES-2) using all the available photometry (14 quarters; 1570640 measures) from the NASA Exoplanet Archive (NEA) at the Caltech website http://exoplanetarchive.ipac.caltech.edu. The mean individual data-point error of the normalized flux values is 0.00026, leading to the model's specification for the mean reference flux of the system to an accuracy of {˜} 0.5 ppm. Completion of the analysis requires a number of prior quantities, relating mainly to the host star, that are adopted from relevant literature.

  14. Risk-informed criticality analysis as applied to waste packages subject to a subsurface igneous intrusion

    NASA Astrophysics Data System (ADS)

    Kimball, Darby Suzan

    Practitioners of many branches of nuclear facility safety use probabilistic risk assessment (PRA) methodology, which evaluates the reliability of a system along with the consequences of various failure states. One important exception is nuclear criticality safety, which traditionally produces binary results (critical or subcritical, based upon value of the effective multiplication factor, keff). For complex systems, criticality safety can benefit from application of the more flexible PRA techniques. A new risk-based technique in criticality safety analysis is detailed. In addition to identifying the most reactive configuration(s) and determining subcriticality, it yields more information about the relative reactivity contributions of various factors. By analyzing a more complete system, confidence that the system will remain subcritical is increased and areas where additional safety features would be most effective are indicated. The first step in the method is to create a criticality event tree (a specialized form of event tree where multiple outcomes stemming from a single event are acceptable). The tree lists events that impact reactivity by changing a system parameter. Next, the value of keff is calculated for the end states using traditional methods like the MCNP code. As calculations progress, the criticality event tree is modified; event branches demonstrated to have little effect on reactivity may be collapsed (thus reducing the total number of criticality runs), and branches may be added if more information is needed to characterize the system. When the criticality event tree is mature, critical limits are determined according to traditional validation techniques. Finally, results are evaluated. Criticality for the system is determined by comparing the value of k eff for each end state to the critical limit derived for those cases. The relative contributions of various events to criticality are identified by comparing end states resulting from different

  15. Enterprise Systems Analysis

    DTIC Science & Technology

    2016-03-14

    Systems ...Report No. SERC-2016-TR-103 Copyright © 2016 Stevens Institute of Technology The Systems Engineering Research Center (SERC) is a federally...Stevens Institute of Technology and Systems Engineering Research Center Material is furnished on an “as-is” basis. Stevens Institute of

  16. International publication trends in the Journal of Applied Behavior Analysis: 2000-2014.

    PubMed

    Martin, Neil T; Nosik, Melissa R; Carr, James E

    2016-06-01

    Dymond, Clarke, Dunlap, and Steiner's (2000) analysis of international publication trends in the Journal of Applied Behavior Analysis (JABA) from 1970 to 1999 revealed low numbers of publications from outside North America, leading the authors to express concern about the lack of international involvement in applied behavior analysis. They suggested that a future review would be necessary to evaluate any changes in international authorship in the journal. As a follow-up, we analyzed non-U.S. publication trends in the most recent 15 years of JABA and found similar results. We discuss potential reasons for the relative paucity of international authors and suggest potential strategies for increasing non-U.S. contributions to the advancement of behavior analysis.

  17. Multi-Disciplinary System Reliability Analysis

    NASA Technical Reports Server (NTRS)

    Mahadevan, Sankaran; Han, Song

    1997-01-01

    The objective of this study is to develop a new methodology for estimating the reliability of engineering systems that encompass multiple disciplines. The methodology is formulated in the context of the NESSUS probabilistic structural analysis code developed under the leadership of NASA Lewis Research Center. The NESSUS code has been successfully applied to the reliability estimation of a variety of structural engineering systems. This study examines whether the features of NESSUS could be used to investigate the reliability of systems in other disciplines such as heat transfer, fluid mechanics, electrical circuits etc., without considerable programming effort specific to each discipline. In this study, the mechanical equivalence between system behavior models in different disciplines are investigated to achieve this objective. A new methodology is presented for the analysis of heat transfer, fluid flow, and electrical circuit problems using the structural analysis routines within NESSUS, by utilizing the equivalence between the computational quantities in different disciplines. This technique is integrated with the fast probability integration and system reliability techniques within the NESSUS code, to successfully compute the system reliability of multi-disciplinary systems. Traditional as well as progressive failure analysis methods for system reliability estimation are demonstrated, through a numerical example of a heat exchanger system involving failure modes in structural, heat transfer and fluid flow disciplines.

  18. Performance Analysis on Fault Tolerant Control System

    NASA Technical Reports Server (NTRS)

    Shin, Jong-Yeob; Belcastro, Christine

    2005-01-01

    In a fault tolerant control (FTC) system, a parameter varying FTC law is reconfigured based on fault parameters estimated by fault detection and isolation (FDI) modules. FDI modules require some time to detect fault occurrences in aero-vehicle dynamics. In this paper, an FTC analysis framework is provided to calculate the upper bound of an induced-L(sub 2) norm of an FTC system with existence of false identification and detection time delay. The upper bound is written as a function of a fault detection time and exponential decay rates and has been used to determine which FTC law produces less performance degradation (tracking error) due to false identification. The analysis framework is applied for an FTC system of a HiMAT (Highly Maneuverable Aircraft Technology) vehicle. Index Terms fault tolerant control system, linear parameter varying system, HiMAT vehicle.

  19. The Art World's Concept of Negative Space Applied to System Safety Management

    NASA Technical Reports Server (NTRS)

    Goodin, James Ronald (Ronnie)

    2005-01-01

    Tools from several different disciplines can improve system safety management. This paper relates the Art World with our system safety world, showing useful art schools of thought applied to system safety management, developing an art theory-system safety bridge. This bridge is then used to demonstrate relations with risk management, the legal system, personnel management and basic management (establishing priorities). One goal of this presentation/paper is simply to be a fun diversion from the many technical topics presented during the conference.

  20. The Effects of Machine Components on Bifurcation and Chaos as Applied to Multimachine System

    NASA Astrophysics Data System (ADS)

    Alomari, M. M.; Rodanski, B. S.

    The second system of the IEEE second benchmark model of Subsynchronous Resonance (SSR) is considered. The system can be mathematically modeled as a set of first order nonlinear ordinary differential equations with the compensation factor (µ = Xc/XL) as a bifurcation (control) parameter. So, bifurcation theory can be applied to nonlinear dynamical systems, which can be written as dx/dt = F(x; µ). The effects of machine components, i.e. damper winding, automatic voltage regulator (AVR), and power system stabilizer (PSS) on SSR in power system are studied. The results show that these components affect the locations, number and type of the Hopf bifurcations.

  1. QA system for structural analysis

    NASA Astrophysics Data System (ADS)

    Raiko, Heikki

    The activities to be addressed by an organization involved in structural analysis by numerical methods and/or development and maintenance of such computer codes or systems are described. The requirements are based on International Standard 9001. The interpretation of the requirements is done according to an application presented by a Quality Analysis (QA) working group. The purpose of a quality analysis system is to help anyone to do a better job. Emphasis on technical documentation to speed up operations is recommended. The first steps in implementing a finite element quality assurance system in an organization are as follows: constitute a technical body with responsibility and authority for the analysis quality system; agree on management responsibilities for each quality analysis activity; and review current practices against the quality system standard requirements. Experience shows that it is mainly a process of rationalizing, formalizing, and reinforcing existing practices.

  2. Appliance of Independent Component Analysis to System Intrusion Analysis

    NASA Astrophysics Data System (ADS)

    Ishii, Yoshikazu; Takagi, Tarou; Nakai, Kouji

    In order to analyze the output of the intrusion detection system and the firewall, we evaluated the applicability of ICA(independent component analysis). We developed a simulator for evaluation of intrusion analysis method. The simulator consists of the network model of an information system, the service model and the vulnerability model of each server, and the action model performed on client and intruder. We applied the ICA for analyzing the audit trail of simulated information system. We report the evaluation result of the ICA on intrusion analysis. In the simulated case, ICA separated two attacks correctly, and related an attack and the abnormalities of the normal application produced under the influence of the attach.

  3. Applying Systems Theory to Systemic Change: A Generic Model for Educational Reform.

    ERIC Educational Resources Information Center

    Hansen, Joe B.

    Although educational reformers frequently use the words "system,""systemic change," and "systemic approach," many lack a fundamental understanding of the systems concept. This paper describes the application of systems theory to the problems of educational reform and educational assessment. It introduces basic concepts and principles and describes…

  4. Doppler picture velocimetry applied to hypersonics: automated DPV fringe pattern analysis using the FFT method

    NASA Astrophysics Data System (ADS)

    Pichler, Alexander; George, Alfred; Seiler, Friedrich; Srulijes, Julio; Sauerwein, Berthold

    2009-10-01

    Doppler picture velocimetry (DPV) is a tool for visualizing and measuring the flow velocity distribution of tracer particles in a laser light sheet. A frequency sensitive Michelson interferometer, tuned for detecting the velocity distribution by the Doppler effect, visualizes the velocity information of tracer particles crossing an illuminating laser light sheet as interference fringe patterns. Many efforts have been done to evaluate best these DPV patterns, in order to obtain the frequency distribution and, by applying the Doppler formula, the velocity profile of the tracers. The first processing method, developed in 1982, relied on manual processing of the pictures by the user, due to the unavailability of suitable high performance picture processing algorithms. This drawback made DPV being considered as a rather time-consuming measurement technique with limited accuracy, compared to existing commercial velocity measurement systems (e.g. PIV). This is no more the state of the art: The new DPV analysis software, presented in this paper, allows automated processing of the interference fringe samples obtained by two images, a reference picture without frequency shift and a Doppler picture containing the frequency shift, using single beam velocimetry. Based on Fast Fourier transformation (FFT), the presented algorithm determines the corresponding velocity profile (in pseudo colours) within only a few seconds on a standard personal computer without user intervention.

  5. Applying Monte Carlo Simulation to Launch Vehicle Design and Requirements Analysis

    NASA Technical Reports Server (NTRS)

    Hanson, J. M.; Beard, B. B.

    2010-01-01

    This Technical Publication (TP) is meant to address a number of topics related to the application of Monte Carlo simulation to launch vehicle design and requirements analysis. Although the focus is on a launch vehicle application, the methods may be applied to other complex systems as well. The TP is organized so that all the important topics are covered in the main text, and detailed derivations are in the appendices. The TP first introduces Monte Carlo simulation and the major topics to be discussed, including discussion of the input distributions for Monte Carlo runs, testing the simulation, how many runs are necessary for verification of requirements, what to do if results are desired for events that happen only rarely, and postprocessing, including analyzing any failed runs, examples of useful output products, and statistical information for generating desired results from the output data. Topics in the appendices include some tables for requirements verification, derivation of the number of runs required and generation of output probabilistic data with consumer risk included, derivation of launch vehicle models to include possible variations of assembled vehicles, minimization of a consumable to achieve a two-dimensional statistical result, recontact probability during staging, ensuring duplicated Monte Carlo random variations, and importance sampling.

  6. Evolution of Applied Behavior Analysis in the Treatment of Individuals With Autism

    ERIC Educational Resources Information Center

    Wolery, Mark; Barton, Erin E.; Hine, Jeffrey F.

    2005-01-01

    Two issues of each volume of the Journal of Applied Behavior Analysis were reviewed to identify research reports focusing on individuals with autism. The identified articles were analyzed to describe the ages of individuals with autism, the settings in which the research occurred, the nature of the behaviors targeted for intervention, and the…

  7. Using Applied Behaviour Analysis as Standard Practice in a UK Special Needs School

    ERIC Educational Resources Information Center

    Foran, Denise; Hoerger, Marguerite; Philpott, Hannah; Jones, Elin Walker; Hughes, J. Carl; Morgan, Jonathan

    2015-01-01

    This article describes how applied behaviour analysis can be implemented effectively and affordably in a maintained special needs school in the UK. Behaviour analysts collaborate with classroom teachers to provide early intensive behaviour education for young children with autism spectrum disorders (ASD), and function based behavioural…

  8. Applied Behavior Analysis in the Treatment of Severe Psychiatric Disorders: A Bibliography.

    ERIC Educational Resources Information Center

    Scotti, Joseph R.; And Others

    Clinical research in the area of severe psychiatric disorders constituted the major focus for the discipline of applied behavior analysis during the early 1960s. Recently, however, there appears to be a notable lack of a behavioral focus within many inpatient psychiatric settings and a relative dearth of published behavioral treatment studies with…

  9. Applied Behavior Analysis in Autism Spectrum Disorders: Recent Developments, Strengths, and Pitfalls

    ERIC Educational Resources Information Center

    Matson, Johnny L.; Turygin, Nicole C.; Beighley, Jennifer; Rieske, Robert; Tureck, Kimberly; Matson, Michael L.

    2012-01-01

    Autism has become one of the most heavily researched topics in the field of mental health and education. While genetics has been the most studied of all topics, applied behavior analysis (ABA) has also received a great deal of attention, and has arguably yielded the most promising results of any research area to date. The current paper provides a…

  10. Graphical and Numerical Descriptive Analysis: Exploratory Tools Applied to Vietnamese Data

    ERIC Educational Resources Information Center

    Haughton, Dominique; Phong, Nguyen

    2004-01-01

    This case study covers several exploratory data analysis ideas, the histogram and boxplot, kernel density estimates, the recently introduced bagplot--a two-dimensional extension of the boxplot--as well as the violin plot, which combines a boxplot with a density shape plot. We apply these ideas and demonstrate how to interpret the output from these…

  11. Applied Behavior Analysis Programs for Autism: Sibling Psychosocial Adjustment during and Following Intervention Use

    ERIC Educational Resources Information Center

    Cebula, Katie R.

    2012-01-01

    Psychosocial adjustment in siblings of children with autism whose families were using a home-based, applied behavior analysis (ABA) program was compared to that of siblings in families who were not using any intensive autism intervention. Data gathered from parents, siblings and teachers indicated that siblings in ABA families experienced neither…

  12. A Self-Administered Parent Training Program Based upon the Principles of Applied Behavior Analysis

    ERIC Educational Resources Information Center

    Maguire, Heather M.

    2012-01-01

    Parents often respond to challenging behavior exhibited by their children in such a way that unintentionally strengthens it. Applied behavior analysis (ABA) is a research-based science that has been proven effective in remediating challenging behavior in children. Although many parents could benefit from using strategies from the field of ABA with…

  13. A National UK Census of Applied Behavior Analysis School Provision for Children with Autism

    ERIC Educational Resources Information Center

    Griffith, G. M.; Fletcher, R.; Hastings, R. P.

    2012-01-01

    Over more than a decade, specialist Applied Behavior Analysis (ABA) schools or classes for children with autism have developed in the UK and Ireland. However, very little is known internationally about how ABA is defined in practice in school settings, the characteristics of children supported in ABA school settings, and the staffing structures…

  14. Applied Behaviour Analysis: Does Intervention Intensity Relate to Family Stressors and Maternal Well-Being?

    ERIC Educational Resources Information Center

    Schwichtenberg, A.; Poehlmann, J.

    2007-01-01

    Background: Interventions based on applied behaviour analysis (ABA) are commonly recommended for children with an autism spectrum disorder (ASD); however, few studies address how this intervention model impacts families. The intense requirements that ABA programmes place on children and families are often cited as a critique of the programme,…

  15. Conversation after Right Hemisphere Brain Damage: Motivations for Applying Conversation Analysis

    ERIC Educational Resources Information Center

    Barnes, Scott; Armstrong, Elizabeth

    2010-01-01

    Despite the well documented pragmatic deficits that can arise subsequent to Right Hemisphere Brain Damage (RHBD), few researchers have directly studied everyday conversations involving people with RHBD. In recent years, researchers have begun applying Conversation Analysis (CA) to the everyday talk of people with aphasia. This research programme…

  16. A Case Study in the Misrepresentation of Applied Behavior Analysis in Autism: The Gernsbacher Lectures

    PubMed Central

    Morris, Edward K

    2009-01-01

    I know that most men, including those at ease with problems of the greatest complexity, can seldom accept the simplest and most obvious truth if it be such as would oblige them to admit the falsity of conclusions which they have proudly taught to others, and which they have woven, thread by thread, into the fabrics of their life. (Tolstoy, 1894) This article presents a case study in the misrepresentation of applied behavior analysis for autism based on Morton Ann Gernsbacher's presentation of a lecture titled “The Science of Autism: Beyond the Myths and Misconceptions.” Her misrepresentations involve the characterization of applied behavior analysis, descriptions of practice guidelines, reviews of the treatment literature, presentations of the clinical trials research, and conclusions about those trials (e.g., children's improvements are due to development, not applied behavior analysis). The article also reviews applied behavior analysis' professional endorsements and research support, and addresses issues in professional conduct. It ends by noting the deleterious effects that misrepresenting any research on autism (e.g., biological, developmental, behavioral) have on our understanding and treating it in a transdisciplinary context. PMID:22478522

  17. Lovaas Model of Applied Behavior Analysis. What Works Clearinghouse Intervention Report

    ERIC Educational Resources Information Center

    What Works Clearinghouse, 2010

    2010-01-01

    The "Lovaas Model of Applied Behavior Analysis" is a type of behavioral therapy that initially focuses on discrete trials: brief periods of one-on-one instruction, during which a teacher cues a behavior, prompts the appropriate response, and provides reinforcement to the child. Children in the program receive an average of 35 to 40 hours…

  18. Says Who?: Students Apply Their Critical-Analysis Skills to Fight Town Hall

    ERIC Educational Resources Information Center

    Trimarchi, Ruth

    2002-01-01

    For some time the author looked for a tool to let students apply what they are learning about critical analysis in the science classroom to a relevant life experience. The opportunity occurred when a proposal to use environmentally friendly cleaning products in town buildings appeared on the local town meeting agenda. Using a copy of the proposal…

  19. Logical Criteria Applied in Writing and in Editing by Text Analysis.

    ERIC Educational Resources Information Center

    Mandersloot, Wim G. B.

    1996-01-01

    Argues that technical communication editing is most effective if it deals with structure first, and that structure deficiencies can be detected by applying a range of logical analysis criteria to each text part. Concludes that lists, headings, classifications, and organograms must comply with the laws of categorization and relevant logical…

  20. Neuro-fuzzy identification applied to fault detection in nonlinear systems

    NASA Astrophysics Data System (ADS)

    Blázquez, L. Felipe; de Miguel, Luis J.; Aller, Fernando; Perán, José R.

    2011-10-01

    This article describes a fault detection method, based on the parity equations approach, to be applied to nonlinear systems. The input-output nonlinear model of the plant, used in the method, has been obtained by a neural fuzzy inference architecture and its learning algorithm. The proposed method is able to detect small abrupt faults, even in systems with unknown nonlinearities. This method has been applied to a real industrial pilot plant, and good performance has been obtained for the experimental case of fault detection in the level sensor of a level control process in the said industrial pilot plant.

  1. Design of Astrometric Mission (JASMINE) by Applying Model Driven System Engineering

    NASA Astrophysics Data System (ADS)

    Yamada, Y.; Miyashita, H.; Nakamura, H.; Suenaga, K.; Kamiyoshi, S.; Tsuiki, A.

    2010-12-01

    We are planning space astrometric satellite mission named JASMINE. The target accuracy of parallaxes in JASMINE observation is 10 micro arc second, which corresponds to 1 nm scale on the focal plane. It is very hard to measure the 1 nm scale deformation of focal plane. Eventually, we need to add the deformation to the observation equations when estimating stellar astrometric parameters, which requires considering many factors such as instrument models and observation data analysis. In this situation, because the observation equations become more complex, we may reduce the stability of the hardware, nevertheless, we require more samplings due to the lack of rigidity of each estimation. This mission imposes a number of trades-offs in the engineering choices and then decide the optimal design from a number of candidates. In order to efficiently support such decisions, we apply Model Driven Systems Engineering (MDSE), which improves the efficiency of the engineering by revealing and formalizing requirements, specifications, and designs to find a good balance among various trade-offs.

  2. Earth resources data analysis system

    NASA Technical Reports Server (NTRS)

    1972-01-01

    The Earth Resources Laboratory Data Analysis System provides a valuable research tool in the evaluation of multispectral, radiometric, photographic, and passive microwave imagery data. The system has been in operational use for several months and has performed quite well. Emphasis on versatility of both the hardware and software design facilitates system expansion to many specialized data analysis tasks. The many independent software handlers provide building blocks for major processing programs.

  3. A novel digital image processing system for the transient liquid crystal technique applied for heat transfer and film cooling measurements.

    PubMed

    Vogel, G; Boelcs, A

    2001-05-01

    This paper is dedicated to the transient liquid crystal technique measurements for multiple view access by using a novel digital recording and image processing system. The transient liquid crystal technique is widely used for heat transfer investigations in turbomachinery. It has been applied in our laboratory in several test facilities such as a linear cascade for external film cooling measurements or on a ribbed squared duct for internal cooling measurements. The data analysis as well as the measurement equipment is described, with a special focus on the newly developed computerized image processing system suitable to capture the liquid crystal signal.

  4. Laser rocket system analysis

    NASA Technical Reports Server (NTRS)

    Jones, W. S.; Forsyth, J. B.; Skratt, J. P.

    1979-01-01

    The laser rocket systems investigated in this study were for orbital transportation using space-based, ground-based and airborne laser transmitters. The propulsion unit of these systems utilizes a continuous wave (CW) laser beam focused into a thrust chamber which initiates a plasma in the hydrogen propellant, thus heating the propellant and providing thrust through a suitably designed nozzle and expansion skirt. The specific impulse is limited only by the ability to adequately cool the thruster and the amount of laser energy entering the engine. The results of the study showed that, with advanced technology, laser rocket systems with either a space- or ground-based laser transmitter could reduce the national budget allocated to space transportation by 10 to 345 billion dollars over a 10-year life cycle when compared to advanced chemical propulsion systems (LO2-LH2) of equal capability. The variation in savings depends upon the projected mission model.

  5. The pyramid system for multiscale raster analysis

    USGS Publications Warehouse

    De Cola, L.; Montagne, N.

    1993-01-01

    Geographical research requires the management and analysis of spatial data at multiple scales. As part of the U.S. Geological Survey's global change research program a software system has been developed that reads raster data (such as an image or digital elevation model) and produces a pyramid of aggregated lattices as well as various measurements of spatial complexity. For a given raster dataset the system uses the pyramid to report: (1) mean, (2) variance, (3) a spatial autocorrelation parameter based on multiscale analysis of variance, and (4) a monofractal scaling parameter based on the analysis of isoline lengths. The system is applied to 1-km digital elevation model (DEM) data for a 256-km2 region of central California, as well as to 64 partitions of the region. PYRAMID, which offers robust descriptions of data complexity, also is used to describe the behavior of topographic aspect with scale. ?? 1993.

  6. Power Plant Systems Analysis

    NASA Technical Reports Server (NTRS)

    Williams, J. R.; Yang, Y. Y.

    1973-01-01

    Three basic thermodynamic cycles of advanced nuclear MHD power plant systems are studied. The effect of reactor exit temperature and space radiator temperature on the overall thermal efficiency of a regenerative turbine compressor power plant system is shown. The effect of MHD pressure ratio on plant efficiency is also described, along with the dependence of MHD power output, compressor power requirement, turbine power output, mass flow rate of H2, and overall plant efficiency on the reactor exit temperature for a specific configuration.

  7. The Land Analysis System (LAS)

    NASA Technical Reports Server (NTRS)

    Lu, Yun-Chi; Irani, Fred M.

    1991-01-01

    The Land Analysis System (LAS) is an interactive software system, available in the public domain, for the analysis, display, and management of multispectral and other digital image data. The system was developed to support earth sciences research and development activities. LAS provides over 240 applications functions and utilities, a flexible user interface, complete on-line and hardcopy documentation, extensive image data file management, reformatting, and conversion utilities, and high level device independent access to image display hardware. The capabilities are summarized of the latest release of the system (version 5). Emphasis is given to the system portability and the isolation of hardware and software dependencies in this release.

  8. Exergy Analysis of Rocket Systems

    NASA Technical Reports Server (NTRS)

    Gilbert, Andrew; Mesmer, Bryan; Watson, Michael D.

    2015-01-01

    Exergy is defined as the useful work available from a system in a specified environment. Exergy analysis allows for comparison between different system designs, and allows for comparison of subsystem efficiencies within system designs. The proposed paper explores the relationship between the fundamental rocket equation and an exergy balance equation. A previously derived exergy equation related to rocket systems is investigated, and a higher fidelity analysis will be derived. The exergy assessments will enable informed, value-based decision making when comparing alternative rocket system designs, and will allow the most efficient configuration among candidate configurations to be determined.

  9. Operationalizing sustainability in urban coastal systems: a system dynamics analysis.

    PubMed

    Mavrommati, Georgia; Bithas, Kostas; Panayiotidis, Panayiotis

    2013-12-15

    We propose a system dynamics approach for Ecologically Sustainable Development (ESD) in urban coastal systems. A systematic analysis based on theoretical considerations, policy analysis and experts' knowledge is followed in order to define the concept of ESD. The principles underlying ESD feed the development of a System Dynamics Model (SDM) that connects the pollutant loads produced by urban systems' socioeconomic activities with the ecological condition of the coastal ecosystem that it is delineated in operational terms through key biological elements defined by the EU Water Framework Directive. The receiving waters of the Athens Metropolitan area, which bears the elements of typical high population density Mediterranean coastal city but which currently has also new dynamics induced by the ongoing financial crisis, are used as an experimental system for testing a system dynamics approach to apply the concept of ESD. Systems' thinking is employed to represent the complex relationships among the components of the system. Interconnections and dependencies that determine the potentials for achieving ESD are revealed. The proposed system dynamics analysis can facilitate decision makers to define paths of development that comply with the principles of ESD.

  10. Systems analysis with an integrated medical analysis system (IMAS)

    NASA Astrophysics Data System (ADS)

    Koelsch, John; Mabry, Susan L.; Rodriquez, Samuel; Takemura, Paul

    1998-05-01

    This paper describes the integrated medical analysis system (IMAS) The evolving system consists of an integrated suite of models and tools providing quantitative and dynamic analysis from multiple physiological function models, clinical care patient input, medical device data, and integrated medical systems. The system is being developed for requirements definition, patient assessment, control theory, training, instrumentation testing and validation. Traditionally, human models and simulations are performed on small scale, isolated problems, usually consisting of detached mathematical models or measurements studies. These systems are not capable of portraying the interactive effects of such systems and certainly are not capable of integrating multiple external entities such as device data, patient data, etc. The human body in and of itself is a complex, integrated system. External monitors, treatments, and medical conditions interact at yet another level. Hence, a highly integrated, interactive simulation system with detailed subsystem models is required for effective quantitative analysis. The current prototype emphasizes cardiovascular, respiratory and thermoregulatory functions with integration of patient device data. Unique system integration of these components is achieved through four facilitators. These facilitators include a distributed interactive computing architecture, application of fluid and structural engineering principles to the models, real-time scientific visualization, and application of strong system integration principles. The IMAS forms a complex analytical tool with emphasis on integration and interaction at multiple levels between components. This unique level of integration and interaction facilitates quantitative analysis for multiple purposes and varying levels of fidelity. An overview of the project and preliminary findings are introduced.

  11. Performance analysis of continuous tracking laser Doppler vibrometry applied to rotating structures in coast-down

    NASA Astrophysics Data System (ADS)

    Martarelli, M.; Castellini, P.

    2012-06-01

    In this paper a performance analysis of the so-called tracking continuous scanning laser Doppler vibrometry (TCSLDV) exploited in coast-down has been performed. This non-contact measurement system is able to scan continuously over a rotating surface during coast-down and to determine vibration operational deflection shapes (ODSs) and natural frequencies in short time, i.e. the temporal extent of the coast-down. The method is based on a laser Doppler vibrometer (LDV) whose laser beam is driven to scan continuously over the whole rotor surface synchronously with its rotation, so that the LDV output is modulated by the structure's ODSs. This technique has a full-field nature that enables it to measure simultaneously the time and spatial dependence of the vibration in a unique measurement. However, the TCSLDV presents some criticalities in practical applications, especially when applied to rotary transient and fast processes. In fact, if the vibration is transient and decays very fast, then the laser beam could not have had the time to scan the complete structure surface and the modulation of the ODS could be partial. An analytical model reproducing a representative experiment has been developed in order to evaluate the sensitivity of results to testing conditions. The laser beam trajectory in both the fixed and rotating reference systems has been synthesized showing its dependence on experimental parameters as the rotation speed variation during coast-down. It has been demonstrated the decrease in speed induces the deformation of the laser trajectory influencing the LDV output time history, spectrum and consequently the recovered ODS.

  12. System Definition-Enabled Acquisition (SDEA) - A Concept for Defining Requirements for Applying Model-Based Systems Engineering (MBSE) to the Acquisition of DoD Complex Systems

    DTIC Science & Technology

    2012-04-30

    Acquisition (SDEA)—A Concept for Defining Requirements for Applying Model-Based Systems Engineering ( MBSE ) to the Acquisition of DoD Complex Systems...Based Systems Engineering ( MBSE ) to the Acquisition of DoD Complex Systems 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR...Defining Requirements for Applying Model-Based Systems Engineering ( MBSE ) to the Acquisition of DoD Complex Systems Paul Montgomery, Ron Carlson

  13. INDEPENDENT COMPONENT ANALYSIS (ICA) APPLIED TO LONG BUNCH BEAMS IN THE LOS ALAMOS PROTON STORAGE RING

    SciTech Connect

    Kolski, Jeffrey S.; Macek, Robert J.; McCrady, Rodney C.; Pang, Xiaoying

    2012-05-14

    Independent component analysis (ICA) is a powerful blind source separation (BSS) method. Compared to the typical BSS method, principal component analysis (PCA), which is the BSS foundation of the well known model independent analysis (MIA), ICA is more robust to noise, coupling, and nonlinearity. ICA of turn-by-turn beam position data has been used to measure the transverse betatron phase and amplitude functions, dispersion function, linear coupling, sextupole strength, and nonlinear beam dynamics. We apply ICA in a new way to slices along the bunch and discuss the source signals identified as betatron motion and longitudinal beam structure.

  14. Land Analysis System (LAS)

    NASA Technical Reports Server (NTRS)

    Pease, P. B.

    1989-01-01

    Version 4.1 of LAS provides flexible framework for algorithm development and processing and analysis of image data. Over 500,000 lines of code enable image repair, clustering, classification, film processing, geometric registration, radiometric correction, and manipulation of image statistics.

  15. Comparison of Applying FOUR Reduced Order Models to a Global Sensitivity Analysis

    NASA Astrophysics Data System (ADS)

    Zhang, Y.; Oladyshkin, S.; Liu, Y.; Pau, G. S. H.

    2014-12-01

    This study focuses on the comparison of applying four reduced order models (ROMs) to global sensitivity analysis (GSA). ROM is one way to improve computational efficiency in many-query applications such as optimization, uncertainty quantification, sensitivity analysis, inverse modeling where the computational demand can become large. The four ROM methods are: arbitrary Polynomial Chaos (aPC), Gaussian process regression (GPR), cut high dimensional model representation (HDMR), and random sample HDMR. The discussion is mainly based on a global sensitivity analysis performed for a hypothetical large-scale CO2 storage project. Pros and cons of each method will be discussed and suggestions on how each method should be applied individually or combined will be made.

  16. Miniaturized flow injection analysis system

    DOEpatents

    Folta, J.A.

    1997-07-01

    A chemical analysis technique known as flow injection analysis is described, wherein small quantities of chemical reagents and sample are intermixed and reacted within a capillary flow system and the reaction products are detected optically, electrochemically, or by other means. A highly miniaturized version of a flow injection analysis system has been fabricated utilizing microfabrication techniques common to the microelectronics industry. The microflow system uses flow capillaries formed by etching microchannels in a silicon or glass wafer followed by bonding to another wafer, commercially available microvalves bonded directly to the microflow channels, and an optical absorption detector cell formed near the capillary outlet, with light being both delivered and collected with fiber optics. The microflow system is designed mainly for analysis of liquids and currently measures 38{times}25{times}3 mm, but can be designed for gas analysis and be substantially smaller in construction. 9 figs.

  17. Miniaturized flow injection analysis system

    DOEpatents

    Folta, James A.

    1997-01-01

    A chemical analysis technique known as flow injection analysis, wherein small quantities of chemical reagents and sample are intermixed and reacted within a capillary flow system and the reaction products are detected optically, electrochemically, or by other means. A highly miniaturized version of a flow injection analysis system has been fabricated utilizing microfabrication techniques common to the microelectronics industry. The microflow system uses flow capillaries formed by etching microchannels in a silicon or glass wafer followed by bonding to another wafer, commercially available microvalves bonded directly to the microflow channels, and an optical absorption detector cell formed near the capillary outlet, with light being both delivered and collected with fiber optics. The microflow system is designed mainly for analysis of liquids and currently measures 38.times.25.times.3 mm, but can be designed for gas analysis and be substantially smaller in construction.

  18. Applied Nuclear Accountability Systems: A Case Study in the System Architecture and Development of NuMAC

    SciTech Connect

    Campbell, Andrea Beth

    2004-07-01

    This is a case study of the NuMAC nuclear accountability system developed at a private fuel fabrication facility. This paper investigates nuclear material accountability and safeguards by researching expert knowledge applied in the system design and development. Presented is a system developed to detect and deter the theft of weapons grade nuclear material. Examined is the system architecture that includes: issues for the design and development of the system; stakeholder issues; how the system was built and evolved; software design, database design, and development tool considerations; security and computing ethics. (author)

  19. Terrestrial Photovoltaic System Analysis.

    DTIC Science & Technology

    1980-07-01

    tanks is cost Iv (P3 per Watt) bet’aulse ofanll-t distri bution svsteri and uise if exit ic heat. 01latgr 1 C 01:1 li:-iorn. ItIe r e1o0re iS t i a1t...install an array size ot at least 300i kW. The estimated initial instal led cost oi th., cmibiiid phit,)voltaic!tLier- mal system is $28 per watt. The use...conclusion, theretore, is that ;al electric - only photovoltaic system is more cost effective. The daily average power requirement of the

  20. Integrated systems analysis of the PIUS reactor

    SciTech Connect

    Fullwood, F.; Kroeger, P.; Higgins, J.

    1993-11-01

    Results are presented of a systems failure analysis of the PIUS plant systems that are used during normal reactor operation and postulated accidents. This study was performed to provide the NRC with an understanding of the behavior of the plant. The study applied two diverse failure identification methods, Failure Modes Effects & Criticality Analysis (FMECA) and Hazards & Operability (HAZOP) to the plant systems, supported by several deterministic analyses. Conventional PRA methods were also used along with a scheme for classifying events by initiator frequency and combinations of failures. Principal results of this study are: (a) an extensive listing of potential event sequences, grouped in categories that can be used by the NRC, (b) identification of support systems that are important to safety, and (c) identification of key operator actions.

  1. An approach for evaluating the integrity of fuel applied in Innovative Nuclear Energy Systems

    NASA Astrophysics Data System (ADS)

    Nakae, Nobuo; Ozawa, Takayuki; Ohta, Hirokazu; Ogata, Takanari; Sekimoto, Hiroshi

    2014-03-01

    One of the important issues in the study of Innovative Nuclear Energy Systems is evaluating the integrity of fuel applied in Innovative Nuclear Energy Systems. An approach for evaluating the integrity of the fuel is discussed here based on the procedure currently used in the integrity evaluation of fast reactor fuel. The fuel failure modes determining fuel life time were reviewed and fuel integrity was analyzed and compared with the failure criteria.

  2. Expert Meeting Report: Recommendations for Applying Water Heaters in Combination Space and Domestic Water Heating Systems

    SciTech Connect

    Rudd, A.; Ueno, K.; Bergey, D.; Osser, R.

    2012-07-01

    The topic of this meeting was 'Recommendations For Applying Water Heaters In Combination Space And Domestic Water Heating Systems.' Presentations and discussions centered on the design, performance, and maintenance of these combination systems, with the goal of developing foundational information toward the development of a Building America Measure Guideline on this topic. The meeting was held at the Westford Regency Hotel, in Westford, Massachusetts on 7/31/2011.

  3. Research in progress in applied mathematics, numerical analysis, fluid mechanics, and computer science

    NASA Technical Reports Server (NTRS)

    1994-01-01

    This report summarizes research conducted at the Institute for Computer Applications in Science and Engineering in applied mathematics, fluid mechanics, and computer science during the period October 1, 1993 through March 31, 1994. The major categories of the current ICASE research program are: (1) applied and numerical mathematics, including numerical analysis and algorithm development; (2) theoretical and computational research in fluid mechanics in selected areas of interest to LaRC, including acoustics and combustion; (3) experimental research in transition and turbulence and aerodynamics involving LaRC facilities and scientists; and (4) computer science.

  4. 40 CFR 63.8030 - What requirements apply to my heat exchange systems?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... apply to my heat exchange systems? (a) You must comply with the requirements specified in Table 6 to... § 63.10(b)(1). (e) The reference to the periodic report required by § 63.152(c) of subpart G of...

  5. An Investigation of Employees' Use of E-Learning Systems: Applying the Technology Acceptance Model

    ERIC Educational Resources Information Center

    Lee, Yi-Hsuan; Hsieh, Yi-Chuan; Chen, Yen-Hsun

    2013-01-01

    The purpose of this study is to apply the technology acceptance model to examine the employees' attitudes and acceptance of electronic learning (e-learning) systems in organisations. This study examines four factors (organisational support, computer self-efficacy, prior experience and task equivocality) that are believed to influence employees'…

  6. Applying the Systems Approach to Curriculum Development in the Science Classroom.

    ERIC Educational Resources Information Center

    Boblick, John M.

    Described is a method by which a classroom teacher may apply the systems approach to the development of the instructional segments which he uses in his daily teaching activities. The author proposes a three-dimensional curriculum design model and discusses its main features. The basic points which characterize the application of the systems…

  7. Teaching Applied Genetics and Molecular Biology to Agriculture Engineers. Application of the European Credit Transfer System

    ERIC Educational Resources Information Center

    Weiss, J.; Egea-Cortines, M.

    2008-01-01

    We have been teaching applied molecular genetics to engineers and adapted the teaching methodology to the European Credit Transfer System. We teach core principles of genetics that are universal and form the conceptual basis of most molecular technologies. The course then teaches widely used techniques and finally shows how different techniques…

  8. Embracing Connectedness and Change: A Complex Dynamic Systems Perspective for Applied Linguistic Research

    ERIC Educational Resources Information Center

    Cameron, Lynne

    2015-01-01

    Complex dynamic systems (CDS) theory offers a powerful metaphorical model of applied linguistic processes, allowing holistic descriptions of situated phenomena, and addressing the connectedness and change that often characterise issues in our field. A recent study of Kenyan conflict transformation illustrates application of a CDS perspective. Key…

  9. Toward a Blended Ontology: Applying Knowledge Systems to Compare Therapeutic and Toxicological Nanoscale Domains

    EPA Science Inventory

    Bionanomedicine and environmental research share need common terms and ontologies. This study applied knowledge systems, data mining, and bibliometrics used in nano-scale ADME research from 1991 to 2011. The prominence of nano-ADME in environmental research began to exceed the pu...

  10. Critical Education for Systemic Change: A World-Systems Analysis Perspective

    ERIC Educational Resources Information Center

    Griffiths, Tom G.

    2015-01-01

    This paper both draws on, and seeks to apply, world-systems analysis to a broad, critical education project that builds mass schooling's potential contribution to the process of world-systemic change. In short, this is done by first setting out the world-systems analysis account of the current state, and period of transition, of the capitalist…

  11. WASTE COMBUSTION SYSTEM ANALYSIS

    EPA Science Inventory

    The report gives results of a study of biomass combustion alternatives. The objective was to evaluate the thermal performance and costs of available and developing biomass systems. The characteristics of available biomass fuels were reviewed, and the performance parameters of alt...

  12. Controlled ecological life support system: Transportation analysis

    NASA Technical Reports Server (NTRS)

    Gustan, E.; Vinopal, T.

    1982-01-01

    This report discusses a study utilizing a systems analysis approach to determine which NASA missions would benefit from controlled ecological life support system (CELSS) technology. The study focuses on manned missions selected from NASA planning forecasts covering the next half century. Comparison of various life support scenarios for the selected missions and characteristics of projected transportation systems provided data for cost evaluations. This approach identified missions that derived benefits from a CELSS, showed the magnitude of the potential cost savings, and indicated which system or combination of systems would apply. This report outlines the analytical approach used in the evaluation, describes the missions and systems considered, and sets forth the benefits derived from CELSS when applicable.

  13. Energy-Systems Economic Analysis

    NASA Technical Reports Server (NTRS)

    Doane, J.; Slonski, M. L.; Borden, C. S.

    1982-01-01

    Energy Systems Economic Analysis (ESEA) program is flexible analytical tool for rank ordering of alternative energy systems. Basic ESEA approach derives an estimate of those costs incurred as result of purchasing, installing and operating an energy system. These costs, suitably aggregated into yearly costs over lifetime of system, are divided by expected yearly energy output to determine busbar energy costs. ESEA, developed in 1979, is written in FORTRAN IV for batch execution.

  14. Systems analysis-independent analysis and verification

    SciTech Connect

    Badin, J.S.; DiPietro, J.P.

    1995-09-01

    The DOE Hydrogen Program is supporting research, development, and demonstration activities to overcome the barriers to the integration of hydrogen into the Nation`s energy infrastructure. Much work is required to gain acceptance of hydrogen energy system concepts and to develop them for implementation. A systems analysis database has been created that includes a formal documentation of technology characterization profiles and cost and performance information. Through a systematic and quantitative approach, system developers can understand and address important issues and thereby assure effective and timely commercial implementation. This project builds upon and expands the previously developed and tested pathway model and provides the basis for a consistent and objective analysis of all hydrogen energy concepts considered by the DOE Hydrogen Program Manager. This project can greatly accelerate the development of a system by minimizing the risk of costly design evolutions, and by stimulating discussions, feedback, and coordination of key players and allows them to assess the analysis, evaluate the trade-offs, and to address any emerging problem areas. Specific analytical studies will result in the validation of the competitive feasibility of the proposed system and identify system development needs. Systems that are investigated include hydrogen bromine electrolysis, municipal solid waste gasification, electro-farming (biomass gasifier and PEM fuel cell), wind/hydrogen hybrid system for remote sites, home electrolysis and alternate infrastructure options, renewable-based electrolysis to fuel PEM fuel cell vehicle fleet, and geothermal energy used to produce hydrogen. These systems are compared to conventional and benchmark technologies. Interim results and findings are presented. Independent analyses emphasize quality, integrity, objectivity, a long-term perspective, corporate memory, and the merging of technical, economic, operational, and programmatic expertise.

  15. Systems analysis for DSN microwave antenna holography

    NASA Technical Reports Server (NTRS)

    Rochblatt, D. J.

    1989-01-01

    Proposed systems for Deep Space Network (DSN) microwave antenna holography are analyzed. Microwave holography, as applied to antennas, is a technique which utilizes the Fourier Transform relation between the complex far-field radiation pattern of an antenna and the complex aperture field distribution to provide a methodology for the analysis and evaluation of antenna performance. Resulting aperture phase and amplitude distribution data are used to precisely characterize various crucial performance parameters, including panel alignment, subreflector position, antenna aperture illumination, directivity at various frequencies, and gravity deformation. Microwave holographic analysis provides diagnostic capacity as well as being a powerful tool for evaluating antenna design specifications and their corresponding theoretical models.

  16. Applying Chemical Imaging Analysis to Improve Our Understanding of Cold Cloud Formation

    NASA Astrophysics Data System (ADS)

    Laskin, A.; Knopf, D. A.; Wang, B.; Alpert, P. A.; Roedel, T.; Gilles, M. K.; Moffet, R.; Tivanski, A.

    2012-12-01

    The impact that atmospheric ice nucleation has on the global radiation budget is one of the least understood problems in atmospheric sciences. This is in part due to the incomplete understanding of various ice nucleation pathways that lead to ice crystal formation from pre-existing aerosol particles. Studies investigating the ice nucleation propensity of laboratory generated particles indicate that individual particle types are highly selective in their ice nucleating efficiency. This description of heterogeneous ice nucleation would present a challenge when applying to the atmosphere which contains a complex mixture of particles. Here, we employ a combination of micro-spectroscopic and optical single particle analytical methods to relate particle physical and chemical properties with observed water uptake and ice nucleation. Field-collected particles from urban environments impacted by anthropogenic and marine emissions and aging processes are investigated. Single particle characterization is provided by computer controlled scanning electron microscopy with energy dispersive analysis of X-rays (CCSEM/EDX) and scanning transmission X-ray microscopy with near edge X-ray absorption fine structure spectroscopy (STXM/NEXAFS). A particle-on-substrate approach coupled to a vapor controlled cooling-stage and a microscope system is applied to determine the onsets of water uptake and ice nucleation including immersion freezing and deposition ice nucleation as a function of temperature (T) as low as 200 K and relative humidity (RH) up to water saturation. We observe for urban aerosol particles that for T > 230 K the oxidation level affects initial water uptake and that subsequent immersion freezing depends on particle mixing state, e.g. by the presence of insoluble particles. For T < 230 K the particles initiate deposition ice nucleation well below the homogeneous freezing limit. Particles collected throughout one day for similar meteorological conditions show very similar

  17. [Rapid spectrochemical qualitative analysis of simple OMA system].

    PubMed

    Yang, C; Lin, Y; Xu, H; Wen, X; Lin, L

    1997-10-01

    Simple optical multichannel analyzer (OMA) system which is formed by ordinary one dimension CCD camera, spectrograph and microcomputer was introduced in this paper. Spectrochemical analysis feasible of this OMA system was studied. The applied software programed, by us can realize wavelength calibration, spectral line identification and give out automatically the results of qualitative and semidefinite quantity analysis.

  18. A study in the founding of applied behavior analysis through its publications.

    PubMed

    Morris, Edward K; Altus, Deborah E; Smith, Nathaniel G

    2013-01-01

    This article reports a study of the founding of applied behavior analysis through its publications. Our methods included hand searches of sources (e.g., journals, reference lists), search terms (i.e., early, applied, behavioral, research, literature), inclusion criteria (e.g., the field's applied dimension), and (d) challenges to their face and content validity. Our results were 36 articles published between 1959 and 1967 that we organized into 4 groups: 12 in 3 programs of research and 24 others. Our discussion addresses (a) limitations in our method (e.g., the completeness of our search), (b) challenges to the validity of our methods and results (e.g., convergent validity), and (c) priority claims about the field's founding. We conclude that the claims are irresolvable because identification of the founding publications depends significantly on methods and because the field's founding was an evolutionary process. We close with suggestions for future research.

  19. A Study in the Founding of Applied Behavior Analysis Through Its Publications

    PubMed Central

    Morris, Edward K.; Altus, Deborah E.; Smith, Nathaniel G.

    2013-01-01

    This article reports a study of the founding of applied behavior analysis through its publications. Our methods included hand searches of sources (e.g., journals, reference lists), search terms (i.e., early, applied, behavioral, research, literature), inclusion criteria (e.g., the field's applied dimension), and (d) challenges to their face and content validity. Our results were 36 articles published between 1959 and 1967 that we organized into 4 groups: 12 in 3 programs of research and 24 others. Our discussion addresses (a) limitations in our method (e.g., the completeness of our search), (b) challenges to the validity of our methods and results (e.g., convergent validity), and (c) priority claims about the field's founding. We conclude that the claims are irresolvable because identification of the founding publications depends significantly on methods and because the field's founding was an evolutionary process. We close with suggestions for future research. PMID:25729133

  20. Analysis of biomass production systems

    SciTech Connect

    Mishoe, J.W.; Fluck, R.C.; Jones, J.W.; Lorber, M.N.; Peart, R.M.

    1983-06-01

    Methodology is presented to analyze biomass production systems using a modeling and simulation approach. To illustrate the concepts, example studies are presented for sugarcane, water hyacinth, and napier grass. Economics and energetic analysis are described using methane as the output.

  1. 1992 NASA Life Support Systems Analysis workshop

    NASA Technical Reports Server (NTRS)

    Evanich, Peggy L.; Crabb, Thomas M.; Gartrell, Charles F.

    1992-01-01

    The 1992 Life Support Systems Analysis Workshop was sponsored by NASA's Office of Aeronautics and Space Technology (OAST) to integrate the inputs from, disseminate information to, and foster communication among NASA, industry, and academic specialists. The workshop continued discussion and definition of key issues identified in the 1991 workshop, including: (1) modeling and experimental validation; (2) definition of systems analysis evaluation criteria; (3) integration of modeling at multiple levels; and (4) assessment of process control modeling approaches. Through both the 1991 and 1992 workshops, NASA has continued to seek input from industry and university chemical process modeling and analysis experts, and to introduce and apply new systems analysis approaches to life support systems. The workshop included technical presentations, discussions, and interactive planning, with sufficient time allocated for discussion of both technology status and technology development recommendations. Key personnel currently involved with life support technology developments from NASA, industry, and academia provided input to the status and priorities of current and future systems analysis methods and requirements.

  2. The Pulsed Flow Algorithm (PFA) Applied to Coupled Respiratory and Circulatory Systems

    NASA Astrophysics Data System (ADS)

    Staples, A.; Oran, E.; Boris, J.; Kaplan, C.; Kailasanath, K.

    2007-11-01

    The Pulsed Flow Equations (PFE) are a set of coupled partial differential equations designed to capture features particularly relevant to internal flows through flexible elastic channels, such as flows in physiological systems in biological organisms, and hydraulics systems. The equations are an extension of the standard one-dimensional fluid flow equations that, in addition, are able to capture two-dimensional diffusion, branching, transport, viscous, and other effects. A limiting case of the equations is the standard one-dimensional fluid flow equations. The equations are discretized and solved partially using an asymptotic solution, after which they reduce to tridiagonal form. The solution formalism can be applied to many types of complex networks of internal flows, and solves these problems, including some important two-dimensional effects, at the cost of a one-dimensional tridiagonal computation. Here we apply the PFA to describe a coupled circulatory and respiratory system calibrated to the average human body.

  3. Leaching of Particulate and Dissolved Organic Carbon from Compost Applied to Bioretention Systems

    NASA Astrophysics Data System (ADS)

    Iqbal, Hamid; Flury, Markus; Mullane, Jessica; Baig, Muhammad

    2015-04-01

    Compost is used in bioretention systems to improve soil quality, to promote plant growth, and to remove metal contaminants from stormwater. However, compost itself, particularly when applied freshly, can be a source of contamination of the stormwater. To test the potential contamination caused by compost when applied to bioretention systems, we continuously leached a compost column with water under unsaturated conditions and characterized dissolved and particulate organic matter in the leachate. Freshly applied, mature compost leached up to 400 mg/L of dissolved organic carbon and 2,000 mg/L of suspended particulate organic carbon. It required a cumulative water flux of 4,000 mm until concentrations of dissolved and particulate organic carbon declined to levels typical for surface waters. Although, dissolved and particulate organic carbon are not contaminants per se, they can facilitate the movement of metals, thereby enhancing the mobility of toxic metals present in stormwater. Therefore, we recommended that compost is washed before it is applied to bioretention systems. Keywords compost; leachate; alkali extract; dissolved organic carbon; flux

  4. Preliminary Centaur Systems Analysis

    NASA Technical Reports Server (NTRS)

    Maronde, R. G.; Holmes, J. K.; Iwasaki, R. S.

    1981-01-01

    The Centaur is stored in the Orbiter payload bay on the Centaur Integrated Support System (CISS). The CISS not only cradles the Centaur prior to deployment but also provides any signal conditioning required to make the Centaur/Orbiter hardwire interfaces compatible. In addition, the CISS provides other Centaur functions such as controlling all the avionics safety features and providing all the helium supplies for tank pressurizations. Problems associated with a Centaur design concept using a transponder and two switchable antennas are defined. Solutions to these problems are presented.

  5. Applying behavior analysis to clinical problems: review and analysis of habit reversal.

    PubMed Central

    Miltenberger, R G; Fuqua, R W; Woods, D W

    1998-01-01

    This article provides a review and analysis of habit reversal, a multicomponent procedure developed by Azrin and Nunn (1973, 1974) for the treatment of nervous habits, tics, and stuttering. The article starts with a discussion of the behaviors treated with habit reversal, behavioral covariation among habits, and functional analysis and assessment of habits. Research on habit reversal and simplified versions of the procedure is then described. Next the article discusses the limitations of habit reversal and the evidence for its generality. The article concludes with an analysis of the behavioral processes involved in habit reversal and suggestions for future research. PMID:9757583

  6. Information systems vulnerability: A systems analysis perspective

    SciTech Connect

    Wyss, G.D.; Daniel, S.L.; Schriner, H.K.; Gaylor, T.R.

    1996-07-01

    Vulnerability analyses for information systems are complicated because the systems are often geographically distributed. Sandia National Laboratories has assembled an interdisciplinary team to explore the applicability of probabilistic logic modeling (PLM) techniques (including vulnerability and vital area analysis) to examine the risks associated with networked information systems. The authors have found that the reliability and failure modes of many network technologies can be effectively assessed using fault trees and other PLM methods. The results of these models are compatible with an expanded set of vital area analysis techniques that can model both physical locations and virtual (logical) locations to identify both categories of vital areas simultaneously. These results can also be used with optimization techniques to direct the analyst toward the most cost-effective security solution.

  7. Space radiator simulation system analysis

    NASA Technical Reports Server (NTRS)

    Black, W. Z.; Wulff, W.

    1972-01-01

    A transient heat transfer analysis was carried out on a space radiator heat rejection system exposed to an arbitrarily prescribed combination of aerodynamic heating, solar, albedo, and planetary radiation. A rigorous analysis was carried out for the radiation panel and tubes lying in one plane and an approximate analysis was used to extend the rigorous analysis to the case of a curved panel. The analysis permits the consideration of both gaseous and liquid coolant fluids, including liquid metals, under prescribed, time dependent inlet conditions. The analysis provided a method for predicting: (1) transient and steady-state, two dimensional temperature profiles, (2) local and total heat rejection rates, (3) coolant flow pressure in the flow channel, and (4) total system weight and protection layer thickness.

  8. ADVANCED POWER SYSTEMS ANALYSIS TOOLS

    SciTech Connect

    Robert R. Jensen; Steven A. Benson; Jason D. Laumb

    2001-08-31

    The use of Energy and Environmental Research Center (EERC) modeling tools and improved analytical methods has provided key information in optimizing advanced power system design and operating conditions for efficiency, producing minimal air pollutant emissions and utilizing a wide range of fossil fuel properties. This project was divided into four tasks: the demonstration of the ash transformation model, upgrading spreadsheet tools, enhancements to analytical capabilities using the scanning electron microscopy (SEM), and improvements to the slag viscosity model. The ash transformation model, Atran, was used to predict the size and composition of ash particles, which has a major impact on the fate of the combustion system. To optimize Atran key factors such as mineral fragmentation and coalescence, the heterogeneous and homogeneous interaction of the organically associated elements must be considered as they are applied to the operating conditions. The resulting model's ash composition compares favorably to measured results. Enhancements to existing EERC spreadsheet application included upgrading interactive spreadsheets to calculate the thermodynamic properties for fuels, reactants, products, and steam with Newton Raphson algorithms to perform calculations on mass, energy, and elemental balances, isentropic expansion of steam, and gasifier equilibrium conditions. Derivative calculations can be performed to estimate fuel heating values, adiabatic flame temperatures, emission factors, comparative fuel costs, and per-unit carbon taxes from fuel analyses. Using state-of-the-art computer-controlled scanning electron microscopes and associated microanalysis systems, a method to determine viscosity using the incorporation of grey-scale binning acquired by the SEM image was developed. The image analysis capabilities of a backscattered electron image can be subdivided into various grey-scale ranges that can be analyzed separately. Since the grey scale's intensity is

  9. Applying behavior analysis to school violence and discipline problems: Schoolwide positive behavior support

    PubMed Central

    Anderson, Cynthia M.; Kincaid, Donald

    2005-01-01

    School discipline is a growing concern in the United States. Educators frequently are faced with discipline problems ranging from infrequent but extreme problems (e.g., shootings) to less severe problems that occur at high frequency (e.g., bullying, insubordination, tardiness, and fighting). Unfortunately, teachers report feeling ill prepared to deal effectively with discipline problems in schools. Further, research suggests that many commonly used strategies, such as suspension, expulsion, and other reactive strategies, are not effective for ameliorating discipline problems and may, in fact, make the situation worse. The principles and technology of behavior analysis have been demonstrated to be extremely effective for decreasing problem behavior and increasing social skills exhibited by school children. Recently, these principles and techniques have been applied at the level of the entire school, in a movement termed schoolwide positive behavior support. In this paper we review the tenets of schoolwide positive behavior support, demonstrating the relation between this technology and applied behavior analysis. PMID:22478439

  10. Analysis hierarchical model for discrete event systems

    NASA Astrophysics Data System (ADS)

    Ciortea, E. M.

    2015-11-01

    The This paper presents the hierarchical model based on discrete event network for robotic systems. Based on the hierarchical approach, Petri network is analysed as a network of the highest conceptual level and the lowest level of local control. For modelling and control of complex robotic systems using extended Petri nets. Such a system is structured, controlled and analysed in this paper by using Visual Object Net ++ package that is relatively simple and easy to use, and the results are shown as representations easy to interpret. The hierarchical structure of the robotic system is implemented on computers analysed using specialized programs. Implementation of hierarchical model discrete event systems, as a real-time operating system on a computer network connected via a serial bus is possible, where each computer is dedicated to local and Petri model of a subsystem global robotic system. Since Petri models are simplified to apply general computers, analysis, modelling, complex manufacturing systems control can be achieved using Petri nets. Discrete event systems is a pragmatic tool for modelling industrial systems. For system modelling using Petri nets because we have our system where discrete event. To highlight the auxiliary time Petri model using transport stream divided into hierarchical levels and sections are analysed successively. Proposed robotic system simulation using timed Petri, offers the opportunity to view the robotic time. Application of goods or robotic and transmission times obtained by measuring spot is obtained graphics showing the average time for transport activity, using the parameters sets of finished products. individually.

  11. Summary of research in applied mathematics, numerical analysis, and computer sciences

    NASA Technical Reports Server (NTRS)

    1986-01-01

    The major categories of current ICASE research programs addressed include: numerical methods, with particular emphasis on the development and analysis of basic numerical algorithms; control and parameter identification problems, with emphasis on effective numerical methods; computational problems in engineering and physical sciences, particularly fluid dynamics, acoustics, and structural analysis; and computer systems and software, especially vector and parallel computers.

  12. Applied behaviour analysis and standard treatment in intellectual disability: 2-year outcomes.

    PubMed

    Hassiotis, Angela; Canagasabey, Anton; Robotham, Daniel; Marston, Louise; Romeo, Renee; King, Michael

    2011-06-01

    Applied behaviour analysis by a specialist team plus standard treatment for adults with intellectual disability displaying challenging behaviour was reported to be clinically and cost-effective after 6 months. In a 2-year follow-up of the same trial cohort, participants receiving the specialist intervention had significantly lower total and subdomain Aberrant Behavior Checklist scores than those receiving usual care alone. After adjustment for baseline covariates there was no significant difference in costs between the trial arms.

  13. Applying the least restrictive alternative principle to treatment decisions: A legal and behavioral analysis

    PubMed Central

    Johnston, J. M.; Sherman, Robert A.

    1993-01-01

    The least restrictive alternative concept is widely used in mental health law. This paper addresses how the concept has been applied to treatment decisions. The paper offers both a legal and a behavioral analysis to some problems that have emerged in recent years concerning the selection of behavioral procedures used to change client behavior. The paper also offers ways of improving the application of the concept, which involve developing a more behaviorally functional perspective toward restrictiveness. PMID:22478138

  14. Thermal Analysis System

    NASA Technical Reports Server (NTRS)

    DiStefano, III, Frank James (Inventor); Wobick, Craig A. (Inventor); Chapman, Kirt Auldwin (Inventor); McCloud, Peter L. (Inventor)

    2014-01-01

    A thermal fluid system modeler including a plurality of individual components. A solution vector is configured and ordered as a function of one or more inlet dependencies of the plurality of individual components. A fluid flow simulator simulates thermal energy being communicated with the flowing fluid and between first and second components of the plurality of individual components. The simulation extends from an initial time to a later time step and bounds heat transfer to be substantially between the flowing fluid, walls of tubes formed in each of the individual components of the plurality, and between adjacent tubes. Component parameters of the solution vector are updated with simulation results for each of the plurality of individual components of the simulation.

  15. The Applied Behavior Analysis Research Paradigm and Single-Subject Designs in Adapted Physical Activity Research.

    PubMed

    Haegele, Justin A; Hodge, Samuel Russell

    2015-10-01

    There are basic philosophical and paradigmatic assumptions that guide scholarly research endeavors, including the methods used and the types of questions asked. Through this article, kinesiology faculty and students with interests in adapted physical activity are encouraged to understand the basic assumptions of applied behavior analysis (ABA) methodology for conducting, analyzing, and presenting research of high quality in this paradigm. The purposes of this viewpoint paper are to present information fundamental to understanding the assumptions undergirding research methodology in ABA, describe key aspects of single-subject research designs, and discuss common research designs and data-analysis strategies used in single-subject studies.

  16. RGB photoelasticity applied to the analysis of membrane residual stress in glass

    NASA Astrophysics Data System (ADS)

    Ajovalasit, A.; Petrucci, G.; Scafidi, M.

    2012-02-01

    The measurement of residual stresses is of great relevance in the glass industry. The analysis of residual stress in glass is usually made by photoelastic methods because glass is a photoelastic material. This paper considers the determination of membrane residual stresses in glass plates by automatic digital photoelasticity in white light (RGB photoelasticity). The proposed method is applied to the analysis of membrane residual stresses in some tempered glass. The proposed method can effectively replace manual methods based on the use of white light, which are currently provided by some technical standards.

  17. Improving skill development: an exploratory study comparing a philosophical and an applied ethical analysis technique

    NASA Astrophysics Data System (ADS)

    Al-Saggaf, Yeslam; Burmeister, Oliver K.

    2012-09-01

    This exploratory study compares and contrasts two types of critical thinking techniques; one is a philosophical and the other an applied ethical analysis technique. The two techniques analyse an ethically challenging situation involving ICT that a recent media article raised to demonstrate their ability to develop the ethical analysis skills of ICT students and professionals. In particular the skill development focused on includes: being able to recognise ethical challenges and formulate coherent responses; distancing oneself from subjective judgements; developing ethical literacy; identifying stakeholders; and communicating ethical decisions made, to name a few.

  18. Galvanic Liquid Applied Coating System for Protection of Embedded Steel Surfaces from Corrosion

    NASA Technical Reports Server (NTRS)

    Curran, Joseph; MacDowell, Louis; Voska, N. (Technical Monitor)

    2002-01-01

    The corrosion of reinforcing steel in concrete is an insidious problem for the Kennedy Space Center, government agencies, and the general public. Existing corrosion protection systems on the market are costly, complex, and time-consuming to install, require continuous maintenance and monitoring, and require specialized skills for installation. NASA's galvanic liquid-applied coating offers companies the ability to conveniently protect embedded steel rebar surfaces from corrosion. Liquid-applied inorganic galvanic coating contains one ore more of the following metallic particles: magnesium, zinc, or indium and may contain moisture attracting compounds that facilitate the protection process. The coating is applied to the outer surface of reinforced concrete so that electrical current is established between metallic particles and surfaces of embedded steel rebar; and electric (ionic) current is responsible for providing the necessary cathodic protection for embedded rebar surfaces.

  19. Analysis of Combustion Systems

    NASA Technical Reports Server (NTRS)

    Bain, Daniel B.; Smith, Clifford E.; Holderman, James D. (Technical Monitor)

    2003-01-01

    As part of the NASA High-Speed Research Program, low emission combustors are being studied and demonstrated. One combustor concept that is currently being studied and evaluated is the Rich burn-Quick mix-Lean burn (RQL) combustor. The quick-mix zone of the RQL combustor is extremely important in reducing NO(x) emissions; rapid mixing of the bypass airflow with rich-born effluent is essential. The basic challenge can be described as rapid jet-in-crossflow mixing. Although jet-in-crossflow mixing is not new, this RQL application is unique in that the jet-to-mainstream mass-flow ratios are higher than studied previously (approx. 3 in RQL applications versus approx. 0.5 in dilution zone studies), plus the emphasis is on reducing NO(x) emissions (i.e. good mixing might not necessarily produce low emissions). This five-years project focused on identifying quick-mix method that would reduce NO(x) emissions in RQL combustor. The work included study of mixing concepts, and the development of design methodology. Three dimension CFD analysis was the primary tool used in assessing concept and developing design methodology for low emission. Isothermal and reacting CFD calculations were performed on cylindrical, rectangular, and annular generic geometries. Systematic parameters studies were performed to isolate key design parameters and their influence on mixing and emissions.

  20. Ongoing Analysis of Rocket Based Combined Cycle Engines by the Applied Fluid Dynamics Analysis Group at Marshall Space Flight Center

    NASA Technical Reports Server (NTRS)

    Ruf, Joseph; Holt, James B.; Canabal, Francisco

    1999-01-01

    This paper presents the status of analyses on three Rocket Based Combined Cycle configurations underway in the Applied Fluid Dynamics Analysis Group (TD64). TD64 is performing computational fluid dynamics analysis on a Penn State RBCC test rig, the proposed Draco axisymmetric RBCC engine and the Trailblazer engine. The intent of the analysis on the Penn State test rig is to benchmark the Finite Difference Navier Stokes code for ejector mode fluid dynamics. The Draco engine analysis is a trade study to determine the ejector mode performance as a function of three engine design variables. The Trailblazer analysis is to evaluate the nozzle performance in scramjet mode. Results to date of each analysis are presented.

  1. System safety engineering analysis handbook

    NASA Technical Reports Server (NTRS)

    Ijams, T. E.

    1972-01-01

    The basic requirements and guidelines for the preparation of System Safety Engineering Analysis are presented. The philosophy of System Safety and the various analytic methods available to the engineering profession are discussed. A text-book description of each of the methods is included.

  2. Speech Analysis Systems: An Evaluation.

    ERIC Educational Resources Information Center

    Read, Charles; And Others

    1992-01-01

    Performance characteristics are reviewed for seven computerized systems marketed for acoustic speech analysis: CSpeech, CSRE, ILS-PC, Kay Elemetrics model 550 Sona-Graph, MacSpeech Lab II, MSL, and Signalyze. Characteristics reviewed include system components, basic capabilities, documentation, user interface, data formats and journaling, and…

  3. Residual energy applications program systems analysis report

    SciTech Connect

    Yngve, P.W.

    1980-10-01

    Current DOE plans call for building an Energy Applied Systems Test (EAST) Facility at the Savannah River Plant in close proximity to the 140 to 150/sup 0/F waste heat from one of several operating nuclear reactors. The waste water flow from each reactor, approximately 165,000 gpm, provides a unique opportunity to test the performance and operating characteristics of large-scale waste heat power generation and heat pump system concepts. This report provides a preliminary description of the potential end-use market, parametric data on heat pump and the power generation system technology, a preliminary listing of EAST Facility requirements, and an example of an integrated industrial park utilizing the technology to maximize economic pay back. The parametric heat pump analysis concluded that dual-fluid Rankine cycle heat pumps with capacities as high as 400 x 10/sup 6/ Btu/h, can utilize large sources of low temperature residual heat to provide 300/sup 0/F saturatd steam for an industrial park. The before tax return on investment for this concept is 36.2%. The analysis also concluded that smaller modular heat pumps could fulfill the same objective while sacrificing only a moderate rate of return. The parametric power generation analysis concluded that multi-pressure Rankine cycle systems not only are superior to single pressure systems, but can also be developed for large systems (approx. = 17 MW/sub e/). This same technology is applicable to smaller systems at the sacrifice of higher investment per unit output.

  4. Model predictive control based on reduced order models applied to belt conveyor system.

    PubMed

    Chen, Wei; Li, Xin

    2016-11-01

    In the paper, a model predictive controller based on reduced order model is proposed to control belt conveyor system, which is an electro-mechanics complex system with long visco-elastic body. Firstly, in order to design low-degree controller, the balanced truncation method is used for belt conveyor model reduction. Secondly, MPC algorithm based on reduced order model for belt conveyor system is presented. Because of the error bound between the full-order model and reduced order model, two Kalman state estimators are applied in the control scheme to achieve better system performance. Finally, the simulation experiments are shown that balanced truncation method can significantly reduce the model order with high-accuracy and model predictive control based on reduced-model performs well in controlling the belt conveyor system.

  5. The transfer function method for gear system dynamics applied to conventional and minimum excitation gearing designs

    NASA Technical Reports Server (NTRS)

    Mark, W. D.

    1982-01-01

    A transfer function method for predicting the dynamic responses of gear systems with more than one gear mesh is developed and applied to the NASA Lewis four-square gear fatigue test apparatus. Methods for computing bearing-support force spectra and temporal histories of the total force transmitted by a gear mesh, the force transmitted by a single pair of teeth, and the maximum root stress in a single tooth are developed. Dynamic effects arising from other gear meshes in the system are included. A profile modification design method to minimize the vibration excitation arising from a pair of meshing gears is reviewed and extended. Families of tooth loading functions required for such designs are developed and examined for potential excitation of individual tooth vibrations. The profile modification design method is applied to a pair of test gears.

  6. Electrostatic analysis of nanoelectromechanical systems

    NASA Astrophysics Data System (ADS)

    Xu, Yang

    We present a multiscale method, seamlessly combining semiclassical, effective-mass Schrodinger (EMS), and tight-binding (TB) theories proposed for electrostatic analysis of silicon nanoelectromechanical systems (NEMS). By using appropriate criteria, we identify the physical models that are accurate in each local region. If the local physical model is semiclassical, the charge density is directly computed by the semiclassical theory. If the local physical model is quantum-mechanical (EMS or TB model), the charge density is calculated by using the theory of local density of states (LDOS). The LDOS is efficiently calculated from Green's function by using Haydock's recursion method where the Green's function is expressed as a continued fraction based on the local Hamiltonian. Once the charge density is determined, a Poisson equation is solved self-consistently to determine the electronic properties. The accuracy and efficiency of the multiscale method are demonstrated by considering several NEMS examples. The multiscale method can be used to compute the effect of surface and interior defects such as vacancies and broken bonds on the performance of microelectromechanical systems (MEMS). By combining multiscale electrostatic analysis with mechanical analysis, we compute the capacitance-voltage and pull-in/pull-out voltages of MEMS switches in the presence of defects in the dielectric oxide layer. Our results indicate that both surface and interior defects can change the pull-in/pull-out voltages significantly. These voltage offsets can lead to an eventual failure of the MEMS switches. The self-consistent TB method is used to investigate carbon nanotube (CNT)-based sensors. We compute the screening effects of semiconducting and metallic single-wall carbon nanotubes (SWNTs) when water molecules and various ions pass through the nanotubes. The trajectories of ions and water molecules are obtained from molecular dynamics (MD) simulations. It is shown that metallic SWNTs have

  7. Optics system design applying a micro-prism array of a single lens stereo image pair.

    PubMed

    Chen, Chien-Yue; Yang, Ting-Ting; Sun, Wen-Shing

    2008-09-29

    In this study we apply a micro-prism array technique to enable a single lens CCD to capture a stereo image for the simulation of double lens vision. A micro-prism array plate serves as the basis for design, which also improves the lightweight and portability of the overall system in addition to lowering the mass-production costs. Most important of all, this design possesses the characteristics of integration compatibility between general-purpose and video camera.

  8. Applying generalized stochastic Petri nets to manufacturing systems containing nonexponential transition functions

    NASA Technical Reports Server (NTRS)

    Watson, James F., III; Desrochers, Alan A.

    1991-01-01

    Generalized stochastic Petri nets (GSPNs) are applied to flexible manufacturing systems (FMSs). Throughput subnets and s-transitions are presented. Two FMS examples containing nonexponential distributions which were analyzed in previous papers by queuing theory and probability theory, respectively, are treated using GSPNs developed using throughput subnets and s-transitions. The GSPN results agree with the previous results, and developing and analyzing the GSPN models are straightforward and relatively easy compared to other methodologies.

  9. A review of dendrogeomorphological research applied to flood risk analysis in Spain

    NASA Astrophysics Data System (ADS)

    Díez-Herrero, A.; Ballesteros, J. A.; Ruiz-Villanueva, V.; Bodoque, J. M.

    2013-08-01

    Over the last forty years, applying dendrogeomorphology to palaeoflood analysis has improved estimates of the frequency and magnitude of past floods worldwide. This paper reviews the main results obtained by applying dendrogeomorphology to flood research in several case studies in Central Spain. These dendrogeomorphological studies focused on the following topics: (1) anatomical analysis to understand the physiological response of trees to flood damage and improve sampling efficiency; (2) compiling robust flood chronologies in ungauged mountain streams, (3) determining flow depth and estimating flood discharge using two-dimensional hydraulic modelling, and comparing them with other palaeostage indicators; (4) calibrating hydraulic model parameters (i.e. Manning roughness); and (5) implementing stochastic-based, cost-benefit analysis to select optimal mitigation measures. The progress made in these areas is presented with suggestions for further research to improve the applicability of dendrogeochronology to palaeoflood studies. Further developments will include new methods for better identification of the causes of specific types of flood damage to trees (e.g. tilted trees) or stable isotope analysis of tree rings to identify the climatic conditions associated with periods of increasing flood magnitude or frequency.

  10. System based practice: a concept analysis

    PubMed Central

    YAZDANI, SHAHRAM; HOSSEINI, FAKHROLSADAT; AHMADY, SOLEIMAN

    2016-01-01

    Introduction Systems-Based Practice (SBP) is one of the six competencies introduced by the ACGME for physicians to provide high quality of care and also the most challenging of them in performance, training, and evaluation of medical students. This concept analysis clarifies the concept of SBP by identifying its components to make it possible to differentiate it from other similar concepts. For proper training of SBP and to ensure these competencies in physicians, it is necessary to have an operational definition, and SBP’s components must be precisely defined in order to provide valid and reliable assessment tools. Methods Walker & Avant’s approach to concept analysis was performed in eight stages: choosing a concept, determining the purpose of analysis, identifying all uses of the concept, defining attributes, identifying a model case, identifying borderline, related, and contrary cases, identifying antecedents and consequences, and defining empirical referents. Results Based on the analysis undertaken, the attributes of SBP includes knowledge of the system, balanced decision between patients’ need and system goals, effective role playing in interprofessional health care team, system level of health advocacy, and acting for system improvement. System thinking and a functional system are antecedents and system goals are consequences. A case model, as well as border, and contrary cases of SBP, has been introduced. Conclusion he identification of SBP attributes in this study contributes to the body of knowledge in SBP and reduces the ambiguity of this concept to make it possible for applying it in training of different medical specialties. Also, it would be possible to develop and use more precise tools to evaluate SBP competency by using empirical referents of the analysis. PMID:27104198

  11. Nonlinear and non-Hermitian optical systems applied to the development of filters and optical sensors

    NASA Astrophysics Data System (ADS)

    Amaro de Faria Júnior, A. C.

    2015-09-01

    In this work we present a method of investigation of nonlinear optical beams generated from non-Hermitian optical systems1 . This method can be applied in the development of optical filters and optical sensors to process, analyze and choose the passband of the propagation modes of an optical pulse from an non-Hermitian optical system. Non-Hermitian optical systems can be used to develop optical fiber sensors that suppress certain propagation modes of optical pulses that eventually behave as quantum noise. Such systems are described by the Nonlinear Schrödinger-like Equation with Parity-Time (PT) Symmetric Optical Potentials. There are optical fiber sensors that due to high laser intensity and frequency can produce quantum noise, such as Raman and Brillouin scattering. However, the optical fiber, for example, can be designed so that its geometry suppress certain propagation modes of the beam. We apply some results of non- Hermitian optical systems with PT symmetry to simulate optical lattice by a appropriate potential function, which among other applications, can naturally suppress certain propagation modes of an optical beam propagating through a waveguide. In other words, the optical system is modeled by a potential function in the Nonlinear Schrödinger-like Equation that one relates with the geometric aspects of the wave guides and with the optical beam interacting with the waveguide material. The paper is organized as follows: sections 1 and 2 present a brief description about nonlinear optical systems and non-Hermitian optical systems with PT symmetry. Section 3 presents a description of the dynamics of nonlinear optical pulses propagating through optical networks described by a optical potential non-Hermitian. Sections 4 and 5 present a general description of this non-Hermitian optical systems and how to get them from a more general model. Section 6 presents some conclusions and comment and the final section presents the references. Begin the abstract two

  12. Function Analysis and Decomposistion using Function Analysis Systems Technique

    SciTech Connect

    J. R. Wixson

    1999-06-01

    The "Father of Value Analysis", Lawrence D. Miles, was a design engineer for General Electric in Schenectady, New York. Miles developed the concept of function analysis to address difficulties in satisfying the requirements to fill shortages of high demand manufactured parts and electrical components during World War II. His concept of function analysis was further developed in the 1960s by Charles W. Bytheway, a design engineer at Sperry Univac in Salt Lake City, Utah. Charles Bytheway extended Mile's function analysis concepts and introduced the methodology called Function Analysis Systems Techniques (FAST) to the Society of American Value Engineers (SAVE) at their International Convention in 1965 (Bytheway 1965). FAST uses intuitive logic to decompose a high level, or objective function into secondary and lower level functions that are displayed in a logic diagram called a FAST model. Other techniques can then be applied to allocate functions to components, individuals, processes, or other entities that accomplish the functions. FAST is best applied in a team setting and proves to be an effective methodology for functional decomposition, allocation, and alternative development.

  13. Function Analysis and Decomposistion using Function Analysis Systems Technique

    SciTech Connect

    Wixson, James Robert

    1999-06-01

    The "Father of Value Analysis", Lawrence D. Miles, was a design engineer for General Electric in Schenectady, New York. Miles developed the concept of function analysis to address difficulties in satisfying the requirements to fill shortages of high demand manufactured parts and electrical components during World War II. His concept of function analysis was further developed in the 1960s by Charles W. Bytheway, a design engineer at Sperry Univac in Salt Lake City, Utah. Charles Bytheway extended Mile's function analysis concepts and introduced the methodology called Function Analysis Systems Technique (FAST) to the Society of American Value Engineers (SAVE) at their International Convention in 1965 (Bytheway 1965). FAST uses intuitive logic to decompose a high level, or objective function into secondary and lower level functions that are displayed in a logic diagram called a FAST model. Other techniques can then be applied to allocate functions to components, individuals, processes, or other entities that accomplish the functions. FAST is best applied in a team setting and proves to be an effective methodology for functional decomposition, allocation, and alternative development.

  14. Quantification of applied dose in irradiated citrus fruits by DNA Comet Assay together with image analysis.

    PubMed

    Cetinkaya, Nurcan; Ercin, Demet; Özvatan, Sümer; Erel, Yakup

    2016-02-01

    The experiments were conducted for quantification of applied dose for quarantine control in irradiated citrus fruits. Citrus fruits exposed to doses of 0.1 to 1.5 kGy and analyzed by DNA Comet Assay. Observed comets were evaluated by image analysis. The tail length, tail moment and tail DNA% of comets were used for the interpretation of comets. Irradiated citrus fruits showed the separated tails from the head of the comet by increasing applied doses from 0.1 to 1.5 kGy. The mean tail length and mean tail moment% levels of irradiated citrus fruits at all doses are significantly different (p < 0.01) from control even for the lowest dose at 0.1 kGy. Thus, DNA Comet Assay may be a practical quarantine control method for irradiated citrus fruits since it has been possible to estimate the applied low doses as small as 0.1 kGy when it is combined with image analysis.

  15. TOA Analysis Applied to Improve ELF/VLF Wave Generation Efficiency at HAARP

    NASA Astrophysics Data System (ADS)

    Fujimaru, S.; Moore, R. C.

    2011-12-01

    Time-of-arrival (TOA) analysis is applied to observations performed during ELF/VLF wave generation experiments at the High-frequency Active Auroral Research Program (HAARP) HF transmitter in Gakona, Alaska. Geometric modulation is used together with a variable pulse length modulation format to determine the ideal arc length maximizing the ELF/VLF signal magnitude observed on the ground. Observations indicate that the ELF/VLF signal magnitude increases with arc length to a certain extent, after which the magnitude decreases. The end result is that an optimal arc length is identified, maximizing ELF/VLF signal magnitude and minimizing the HF power required to produce that magnitude. A standard frequency analysis is presented together with the TOA analysis to provide a complete context for the experimental results.

  16. Weld analysis and control system

    NASA Technical Reports Server (NTRS)

    Kennedy, Larry Z. (Inventor); Rodgers, Michael H. (Inventor); Powell, Bradley W. (Inventor); Burroughs, Ivan A. (Inventor); Goode, K. Wayne (Inventor)

    1994-01-01

    The invention is a Weld Analysis and Control System developed for active weld system control through real time weld data acquisition. Closed-loop control is based on analysis of weld system parameters and weld geometry. The system is adapted for use with automated welding apparatus having a weld controller which is capable of active electronic control of all aspects of a welding operation. Enhanced graphics and data displays are provided for post-weld analysis. The system provides parameter acquisition, including seam location which is acquired for active torch cross-seam positioning. Torch stand-off is also monitored for control. Weld bead and parent surface geometrical parameters are acquired as an indication of weld quality. These parameters include mismatch, peaking, undercut, underfill, crown height, weld width, puddle diameter, and other measurable information about the weld puddle regions, such as puddle symmetry, etc. These parameters provide a basis for active control as well as post-weld quality analysis and verification. Weld system parameters, such as voltage, current and wire feed rate, are also monitored and archived for correlation with quality parameters.

  17. A reflective lens: applying critical systems thinking and visual methods to ecohealth research.

    PubMed

    Cleland, Deborah; Wyborn, Carina

    2010-12-01

    Critical systems methodology has been advocated as an effective and ethical way to engage with the uncertainty and conflicting values common to ecohealth problems. We use two contrasting case studies, coral reef management in the Philippines and national park management in Australia, to illustrate the value of critical systems approaches in exploring how people respond to environmental threats to their physical and spiritual well-being. In both cases, we used visual methods--participatory modeling and rich picturing, respectively. The critical systems methodology, with its emphasis on reflection, guided an appraisal of the research process. A discussion of these two case studies suggests that visual methods can be usefully applied within a critical systems framework to offer new insights into ecohealth issues across a diverse range of socio-political contexts. With this article, we hope to open up a conversation with other practitioners to expand the use of visual methods in integrated research.

  18. A simplification of the fractional Hartley transform applied to image security system in phase

    NASA Astrophysics Data System (ADS)

    Jimenez, Carlos J.; Vilardy, Juan M.; Perez, Ronal

    2017-01-01

    In this work we develop a new encryption system for encoded image in phase using the fractional Hartley transform (FrHT), truncation operations and random phase masks (RPMs). We introduce a simplification of the FrHT with the purpose of computing this transform in an efficient and fast way. The security of the encryption system is increased by using nonlinear operations, such as the phase encoding and the truncation operations. The image to encrypt (original image) is encoded in phase and the truncation operations applied in the encryption-decryption system are the amplitude and phase truncations. The encrypted image is protected by six keys, which are the two fractional orders of the FrHTs, the two RPMs and the two pseudorandom code images generated by the amplitude and phase truncation operations. All these keys have to be correct for a proper recovery of the original image in the decryption system. We present digital results that confirm our approach.

  19. Optimization of Peltier current lead for applied superconducting systems with optimum combination of cryo-stages

    NASA Astrophysics Data System (ADS)

    Kawahara, Toshio; Emoto, Masahiko; Watanabe, Hirofumi; Hamabe, Makoto; Sun, Jian; Ivanov, Yury; Yamaguchi, Satarou

    2012-06-01

    The reduction of electric power consumption of the cryo-cooler during the working conditions of applied superconducting systems is important, as superconductivity can only be stored at low temperature and the power required for the cooling determines the efficiency of the systems employed. Use of Peltier current leads (PCLs) represents one key solution to effect heat load reduction on the terminals in systems. On the other hand, the performance of cryo-coolers generally increases as the temperature increases given the higher Carnot efficiency. Therefore, combination with suitable mid-stage temperatures represents one possible approach since the thermal anchor can enhance the performance of the system by reducing the electric power consumption of the cryo-coolers. In this paper, we discuss this possibility utilizing an advanced configuration of PCL with a commercially available high temperature cooler. Over 50% enhancement of the performance is estimated.

  20. Robustness analysis of stochastic biochemical systems.

    PubMed

    Ceska, Milan; Safránek, David; Dražan, Sven; Brim, Luboš

    2014-01-01

    We propose a new framework for rigorous robustness analysis of stochastic biochemical systems that is based on probabilistic model checking techniques. We adapt the general definition of robustness introduced by Kitano to the class of stochastic systems modelled as continuous time Markov Chains in order to extensively analyse and compare robustness of biological models with uncertain parameters. The framework utilises novel computational methods that enable to effectively evaluate the robustness of models with respect to quantitative temporal properties and parameters such as reaction rate constants and initial conditions. We have applied the framework to gene regulation as an example of a central biological mechanism where intrinsic and extrinsic stochasticity plays crucial role due to low numbers of DNA and RNA molecules. Using our methods we have obtained a comprehensive and precise analysis of stochastic dynamics under parameter uncertainty. Furthermore, we apply our framework to compare several variants of two-component signalling networks from the perspective of robustness with respect to intrinsic noise caused by low populations of signalling components. We have successfully extended previous studies performed on deterministic models (ODE) and showed that stochasticity may significantly affect obtained predictions. Our case studies demonstrate that the framework can provide deeper insight into the role of key parameters in maintaining the system functionality and thus it significantly contributes to formal methods in computational systems biology.

  1. Applying latent semantic analysis to large-scale medical image databases.

    PubMed

    Stathopoulos, Spyridon; Kalamboukis, Theodore

    2015-01-01

    Latent Semantic Analysis (LSA) although has been used successfully in text retrieval when applied to CBIR induces scalability issues with large image collections. The method so far has been used with small collections due to the high cost of storage and computational time for solving the SVD problem for a large and dense feature matrix. Here we present an effective and efficient approach of applying LSA skipping the SVD solution of the feature matrix and overcoming in this way the deficiencies of the method with large scale datasets. Early and late fusion techniques are tested and their performance is calculated. The study demonstrates that early fusion of several composite descriptors with visual words increase retrieval effectiveness. It also combines well in a late fusion for mixed (textual and visual) ad hoc and modality classification. The results reported are comparable to state of the art algorithms without including additional knowledge from the medical domain.

  2. Applied Behavior Analysis, Autism, and Occupational Therapy: A Search for Understanding.

    PubMed

    Welch, Christie D; Polatajko, H J

    2016-01-01

    Occupational therapists strive to be mindful, competent practitioners and continuously look for ways to improve practice. Applied behavior analysis (ABA) has strong evidence of effectiveness in helping people with autism achieve goals, yet it does not seem to be implemented in occupational therapy practice. To better understand whether ABA could be an evidence-based option to expand occupational therapy practice, the authors conducted an iterative, multiphase investigation of relevant literature. Findings suggest that occupational therapists apply developmental and sensory approaches to autism treatment. The occupational therapy literature does not reflect any use of ABA despite its strong evidence base. Occupational therapists may currently avoid using ABA principles because of a perception that ABA is not client centered. ABA principles and occupational therapy are compatible, and the two could work synergistically.

  3. An uncertainty analysis of the PVT gauging method applied to sub-critical cryogenic propellant tanks

    NASA Astrophysics Data System (ADS)

    Van Dresar, Neil T.

    2004-06-01

    The PVT (pressure, volume, temperature) method of liquid quantity gauging in low-gravity is based on gas law calculations assuming conservation of pressurant gas within the propellant tank and the pressurant supply bottle. There is interest in applying this method to cryogenic propellant tanks since the method requires minimal additional hardware or instrumentation. To use PVT with cryogenic fluids, a non-condensable pressurant gas (helium) is required. With cryogens, there will be a significant amount of propellant vapor mixed with the pressurant gas in the tank ullage. This condition, along with the high sensitivity of propellant vapor pressure to temperature, makes the PVT method susceptible to substantially greater measurement uncertainty than is the case with less volatile propellants. A conventional uncertainty analysis is applied to example cases of liquid hydrogen and liquid oxygen tanks. It appears that the PVT method may be feasible for liquid oxygen. Acceptable accuracy will be more difficult to obtain with liquid hydrogen.

  4. Advantages and drawbacks of applying periodic time-variant modal analysis to spur gear dynamics

    NASA Astrophysics Data System (ADS)

    Pedersen, Rune; Santos, Ilmar F.; Hede, Ivan A.

    2010-07-01

    A simplified torsional model with a reduced number of degrees-of-freedom is used in order to investigate the potential of the technique. A time-dependent gear mesh stiffness function is introduced and expanded in a Fourier series. The necessary number of Fourier terms is determined in order to ensure sufficient accuracy of the results. The method of time-variant modal analysis is applied, and the changes in the fundamental and the parametric resonance frequencies as a function of the rotational speed of the gears, are found. By obtaining the stationary and parametric parts of the time-dependent modes shapes, the importance of the time-varying component relative to the stationary component is investigated and quantified. The method used for calculation and subsequent sorting of the left and right eigenvectors based on a first order Taylor expansion is explained. The advantages and drawbacks of applying the methodology to wind turbine gearboxes are addressed and elucidated.

  5. Development of double-pulse lasers ablation system for generating gold ion source under applying an electric field

    NASA Astrophysics Data System (ADS)

    Khalil, A. A. I.

    2015-12-01

    Double-pulse lasers ablation (DPLA) technique was developed to generate gold (Au) ion source and produce high current under applying an electric potential in an argon ambient gas environment. Two Q-switched Nd:YAG lasers operating at 1064 and 266 nm wavelengths are combined in an unconventional orthogonal (crossed-beam) double-pulse configuration with 45° angle to focus on a gold target along with a spectrometer for spectral analysis of gold plasma. The properties of gold plasma produced under double-pulse lasers excitation were studied. The velocity distribution function (VDF) of the emitted plasma was studied using a dedicated Faraday-cup ion probe (FCIP) under argon gas discharge. The experimental parameters were optimized to attain the best signal to noise (S/N) ratio. The results depicted that the VDF and current signals depend on the discharge applied voltage, laser intensity, laser wavelength and ambient argon gas pressure. A seven-fold increases in the current signal by increasing the discharge applied voltage and ion velocity under applying double-pulse lasers field. The plasma parameters (electron temperature and density) were also studied and their dependence on the delay (times between the excitation laser pulse and the opening of camera shutter) was investigated as well. This study could provide significant reference data for the optimization and design of DPLA systems engaged in laser induced plasma deposition thin films and facing components diagnostics.

  6. Thermodynamic Vent System Applied as Propellant Delivery System for Air Force

    NASA Technical Reports Server (NTRS)

    1996-01-01

    Responding to a request from the Air Force, NASA Lewis Research Center engineers designed a combination pressure control and propellant delivery system based on thermodynamic vent system (TVS) technology. The Air Force is designing a new type of orbit transfer vehicle that uses energy from sunlight to both propel and power the vehicle. Because this vehicle uses propellant at a substantially slower rate than higher-energy rockets, it needed the Lewis-developed TVS technology for long-duration storage of cryogen propellants. Lewis engineers, in conjunction with industry partners, showed how this TVS technology could also be used to deliver propellant to the thruster. The Air Force has now begun the ground test demonstration phase. After successful completion of ground testing, the Air Force plans to use this technology in a space flight as early as 1999.

  7. Wavelet-based image analysis system for soil texture analysis

    NASA Astrophysics Data System (ADS)

    Sun, Yun; Long, Zhiling; Jang, Ping-Rey; Plodinec, M. John

    2003-05-01

    Soil texture is defined as the relative proportion of clay, silt and sand found in a given soil sample. It is an important physical property of soil that affects such phenomena as plant growth and agricultural fertility. Traditional methods used to determine soil texture are either time consuming (hydrometer), or subjective and experience-demanding (field tactile evaluation). Considering that textural patterns observed at soil surfaces are uniquely associated with soil textures, we propose an innovative approach to soil texture analysis, in which wavelet frames-based features representing texture contents of soil images are extracted and categorized by applying a maximum likelihood criterion. The soil texture analysis system has been tested successfully with an accuracy of 91% in classifying soil samples into one of three general categories of soil textures. In comparison with the common methods, this wavelet-based image analysis approach is convenient, efficient, fast, and objective.

  8. Single CMOS sensor system for high resolution double volume measurement applied to membrane distillation system

    NASA Astrophysics Data System (ADS)

    Lorenz, M. G.; Izquierdo-Gil, M. A.; Sanchez-Reillo, R.; Fernandez-Pineda, C.

    2007-01-01

    Membrane distillation (MD) [1] is a relatively new process that is being investigated world-wide as a low cost, energy saving alternative to conventional separation processes such as distillation and reverse osmosis (RO). This process offers some advantages compared to other more popular separation processes, such as working at room conditions (pressure and temperature); low-grade, waste and/or alternative energy sources such as solar and geothermal energy may be used; a very high level of rejection with inorganic solutions; small equipment can be employed, etc. The driving force in MD processes is the vapor pressure difference across the membrane. A temperature difference is imposed across the membrane, which results in a vapor pressure difference. The principal problem in this kind of system is the accurate measurement of the recipient volume change, especially at very low flows. A cathetometer, with up to 0,05 mm resolution, is the instrument used to take these measurements, but the necessary human intervention makes this instrument not suitable for automated systems. In order to overcome this lack, a high resolution system is proposed, that makes automatic measurements of the volume of both recipients, cold and hot, at a rate of up to 10 times per second.

  9. X-ray microfluorescence with synchrotron radiation applied in the analysis of pigments from ancient Egypt

    NASA Astrophysics Data System (ADS)

    Calza, C.; Anjos, M. J.; Mendonça de Souza, S. M. F.; Brancaglion, A., Jr.; Lopes, R. T.

    2008-01-01

    In this work, X-ray microfluorescence with the synchrotron radiation technique was applied in the analysis of pigments found in decorative paintings in the sarcophagus of an Egyptian mummy. This female mummy, from the Roman Period, which was embalmed with the arms and legs swathed separately is considered one of the most important pieces of the Egyptian Collection from the National Museum (Rio de Janeiro, Brazil). The measurements were performed at the XRF beamline D09B of the Brazilian Synchrotron Light Laboratory (LNLS), using the white beam and a Si(Li) detector with resolution of 165 eV at 5.9 keV. The possible pigments found in the samples were: Egyptian blue, Egyptian green frit, green earth, verdigris, malachite, ochre, realgar, chalk, gypsum, bone white, ivory black and magnetite. Hierarchical cluster analysis (HCA) and principal component analysis (PCA) were applied to the results in order to verify if the samples belong to the same period of a linen wrapping fragment, whose provenance was well established.

  10. A comparative study of multivariable robustness analysis methods as applied to integrated flight and propulsion control

    NASA Technical Reports Server (NTRS)

    Schierman, John D.; Lovell, T. A.; Schmidt, David K.

    1993-01-01

    Three multivariable robustness analysis methods are compared and contrasted. The focus of the analysis is on system stability and performance robustness to uncertainty in the coupling dynamics between two interacting subsystems. Of particular interest is interacting airframe and engine subsystems, and an example airframe/engine vehicle configuration is utilized in the demonstration of these approaches. The singular value (SV) and structured singular value (SSV) analysis methods are compared to a method especially well suited for analysis of robustness to uncertainties in subsystem interactions. This approach is referred to here as the interacting subsystem (IS) analysis method. This method has been used previously to analyze airframe/engine systems, emphasizing the study of stability robustness. However, performance robustness is also investigated here, and a new measure of allowable uncertainty for acceptable performance robustness is introduced. The IS methodology does not require plant uncertainty models to measure the robustness of the system, and is shown to yield valuable information regarding the effects of subsystem interactions. In contrast, the SV and SSV methods allow for the evaluation of the robustness of the system to particular models of uncertainty, and do not directly indicate how the airframe (engine) subsystem interacts with the engine (airframe) subsystem.

  11. Multimodal tissue perfusion imaging using multi-spectral and thermographic imaging systems applied on clinical data

    NASA Astrophysics Data System (ADS)

    Klaessens, John H. G. M.; Nelisse, Martin; Verdaasdonk, Rudolf M.; Noordmans, Herke Jan

    2013-03-01

    Clinical interventions can cause changes in tissue perfusion, oxygenation or temperature. Real-time imaging of these phenomena could be useful for surgical strategy or understanding of physiological regulation mechanisms. Two noncontact imaging techniques were applied for imaging of large tissue areas: LED based multispectral imaging (MSI, 17 different wavelengths 370 nm-880 nm) and thermal imaging (7.5 to 13.5 μm). Oxygenation concentration changes were calculated using different analyzing methods. The advantages of these methods are presented for stationary and dynamic applications. Concentration calculations of chromophores in tissue require right choices of wavelengths The effects of different wavelength choices for hemoglobin concentration calculations were studied in laboratory conditions and consequently applied in clinical studies. Corrections for interferences during the clinical registrations (ambient light fluctuations, tissue movements) were performed. The wavelength dependency of the algorithms were studied and wavelength sets with the best results will be presented. The multispectral and thermal imaging systems were applied during clinical intervention studies: reperfusion of tissue flap transplantation (ENT), effectiveness of local anesthetic block and during open brain surgery in patients with epileptic seizures. The LED multispectral imaging system successfully imaged the perfusion and oxygenation changes during clinical interventions. The thermal images show local heat distributions over tissue areas as a result of changes in tissue perfusion. Multispectral imaging and thermal imaging provide complementary information and are promising techniques for real-time diagnostics of physiological processes in medicine.

  12. Automated Loads Analysis System (ATLAS)

    NASA Technical Reports Server (NTRS)

    Gardner, Stephen; Frere, Scot; O’Reilly, Patrick

    2013-01-01

    ATLAS is a generalized solution that can be used for launch vehicles. ATLAS is used to produce modal transient analysis and quasi-static analysis results (i.e., accelerations, displacements, and forces) for the payload math models on a specific Shuttle Transport System (STS) flight using the shuttle math model and associated forcing functions. This innovation solves the problem of coupling of payload math models into a shuttle math model. It performs a transient loads analysis simulating liftoff, landing, and all flight events between liftoff and landing. ATLAS utilizes efficient and numerically stable algorithms available in MSC/NASTRAN.

  13. Time-of-arrival analysis applied to ELF/VLF wave generation experiments at HAARP

    NASA Astrophysics Data System (ADS)

    Moore, R. C.; Fujimaru, S.

    2012-12-01

    Time-of-arrival (TOA) analysis is applied to observations performed during ELF/VLF wave generation experiments at the High-frequency Active Auroral Research Program (HAARP) HF transmitter in Gakona, Alaska. In 2012, a variety of ELF/VLF wave generation techniques were employed to identify the dominant source altitude for each case. Observations were performed for beat-wave modulation, AM modulation, STF modulation, ICD modulation, and cubic frequency modulation, among others. For each of these cases, we identify the dominant ELF/VLF source altitude and compare the experimental results with theoretical HF heating predictions.

  14. Analysis of Preconditioning and Relaxation Operators for the Discontinuous Galerkin Method Applied to Diffusion

    NASA Technical Reports Server (NTRS)

    Atkins, H. L.; Shu, Chi-Wang

    2001-01-01

    The explicit stability constraint of the discontinuous Galerkin method applied to the diffusion operator decreases dramatically as the order of the method is increased. Block Jacobi and block Gauss-Seidel preconditioner operators are examined for their effectiveness at accelerating convergence. A Fourier analysis for methods of order 2 through 6 reveals that both preconditioner operators bound the eigenvalues of the discrete spatial operator. Additionally, in one dimension, the eigenvalues are grouped into two or three regions that are invariant with order of the method. Local relaxation methods are constructed that rapidly damp high frequencies for arbitrarily large time step.

  15. Applying a family systems lens to proxy decision making in clinical practice and research.

    PubMed

    Rolland, John S; Emanuel, Linda L; Torke, Alexia M

    2017-03-01

    When patients are incapacitated and face serious illness, family members must make medical decisions for the patient. Medical decision sciences give only modest attention to the relationships among patients and their family members, including impact that these relationships have on the decision-making process. A review of the literature reveals little effort to systematically apply a theoretical framework to the role of family interactions in proxy decision making. A family systems perspective can provide a useful lens through which to understand the dynamics of proxy decision making. This article considers the mutual impact of family systems on the processes and outcomes of proxy decision making. The article first reviews medical decision science's evolution and focus on proxy decision making and then reviews a family systems approach, giving particular attention to Rolland's Family Systems Illness Model. A case illustrates how clinical practice and how research would benefit from bringing family systems thinking to proxy decisions. We recommend including a family systems approach in medical decision science research and clinical practices around proxy decisions making. We propose that clinical decisions could be less conflicted and less emotionally troubling for families and clinicians if family systems approaches were included. This perspective opens new directions for research and novel approaches to clinical care. (PsycINFO Database Record

  16. Galvanic Liquid Applied Coating System For Protection of Embedded Steel Surfaces from Corrosion

    NASA Technical Reports Server (NTRS)

    Curran, Joseph; Curran, Jerome; Voska, N. (Technical Monitor)

    2002-01-01

    Corrosion of reinforcing steel in concrete is an insidious problem facing Kennedy Space Center (KSC), other Government Agencies, and the general public. These problems include KSC launch support structures, highway bridge infrastructure, and building structures such as condominium balconies. Due to these problems, the development of a Galvanic Liquid Applied Coating System would be a breakthrough technology having great commercial value for the following industries: Transportation, Infrastructure, Marine Infrastructure, Civil Engineering, and the Construction Industry. This sacrificial coating system consists of a paint matrix that may include metallic components, conducting agents, and moisture attractors. Similar systems have been used in the past with varying degrees of success. These systems have no proven history of effectiveness over the long term. In addition, these types of systems have had limited success overcoming the initial resistance between the concrete/coating interface. The coating developed at KSC incorporates methods proven to overcome the barriers that previous systems could not achieve. Successful development and continued optimization of this breakthrough system would produce great interest in NASA/KSC for corrosion engineering technology and problem solutions. Commercial patents on this technology would enhance KSC's ability to attract industry partners for similar corrosion control applications.

  17. Analysis of asphalt-based roof systems using thermal analysis

    SciTech Connect

    Paroli, R.M.; Delgado, A.H.

    1996-10-01

    Asphalt is used extensively in roofing applications. Traditionally, it is used in a built-up roof system, where four or five plies are applied in conjunction with asphalt. This is labour intensive and requires good quality assurance on the roof top. Alternatively, asphalt can be used in a polymer-modified sheet where styrene-butadiene-styrene (SBS) or atactic polypropylene (APP) are added to the asphalt shipped in a roll where reinforcement (e.g., glass fibre mat) has been added. Regardless of the system used, the roof must be able to withstand the environmental loads such UV, heat, etc. Thermoanalytical techniques such as DSC, DMA, TMA and TG/DTA are ideally suited to monitor the weathering of asphalt. This paper presents data obtained using these techniques and shows how the performance of asphalt-based roof systems can be followed by thermal analysis.

  18. Inter-Enterprise Planning of Manufacturing Systems Applying Simulation with IPR Protection

    NASA Astrophysics Data System (ADS)

    Mertins, Kai; Rabe, Markus

    Discrete Event Simulation is a well-proved method to analyse the dynamic behaviour of manufacturing systems. However, simulation application is still poor for external supply chains or virtual enterprises, encompassing several legal entities. Most conventional simulation systems provide no means to protect intellectual property rights (IPR), nor methods to support cross-enterprise teamwork. This paper describes a solution to keep enterprise models private, but still provide their functionality for cross-enterprise evaluation purposes. Applying the new modelling system, the inter-enterprise business process is specified by the user, including a specification of the objects exchanged between the local models. The required environment for a distributed simulation is generated automatically. The mechanisms have been tested with a large supply chain model.

  19. SU(1,1) Lie Algebra Applied to the General Time-dependent Quadratic Hamiltonian System

    NASA Astrophysics Data System (ADS)

    Choi, J. R.; Nahm, I. H.

    2007-01-01

    Exact quantum states of the time-dependent quadratic Hamiltonian system are investigated using SU(1,1) Lie algebra. We realized SU(1,1) Lie algebra by defining appropriate SU(1,1) generators and derived exact wave functions using this algebra for the system. Raising and lowering operators of SU(1,1) Lie algebra expressed by multiplying a time-constant magnitude and a time-dependent phase factor. Two kinds of the SU(1,1) coherent states, i.e., even and odd coherent states and Perelomov coherent states are studied. We applied our result to the Caldirola-Kanai oscillator. The probability density of these coherent states for the Caldirola-Kanai oscillator converged to the center as time goes by, due to the damping constant γ. All the coherent state probability densities for the driven system are somewhat deformed.

  20. Sender–receiver systems and applying information theory for quantitative synthetic biology

    PubMed Central

    Barcena Menendez, Diego; Senthivel, Vivek Raj; Isalan, Mark

    2015-01-01

    Sender–receiver (S–R) systems abound in biology, with communication systems sending information in various forms. Information theory provides a quantitative basis for analysing these processes and is being applied to study natural genetic, enzymatic and neural networks. Recent advances in synthetic biology are providing us with a wealth of artificial S–R systems, giving us quantitative control over networks with a finite number of well-characterised components. Combining the two approaches can help to predict how to maximise signalling robustness, and will allow us to make increasingly complex biological computers. Ultimately, pushing the boundaries of synthetic biology will require moving beyond engineering the flow of information and towards building more sophisticated circuits that interpret biological meaning. PMID:25282688