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Sample records for applying flagged sysmex

  1. The usefulness of blast flags on the Sysmex XE-5000 is questionable.

    PubMed

    Eilertsen, Heidi; Vøllestad, Nina K; Hagve, Tor-Arne

    2013-05-01

    Hematology analyzers generate suspect flags that involve microscopic reviews to confirm the presence of pathologic cells. This study investigated the reliability of the blast flag in a side-by-side evaluation of 3 Sysmex XE-5000 instruments (Sysmex, Kobe, Japan). The repeatability of the Q values reported by each instrument for 10 replicates of the same blood samples was low (intraclass correlation coefficient [ICC] values, 0.62-0.74). The reproducibility of the Q values obtained by analyzing 408 samples on all 3 instruments was reasonable (ICC value, 0.85). In addition, a systematic difference was observed among the instruments in the level of reported Q values. With cutoff commonly being 100, the observed reproducibility of the blast flagging among the instruments was evaluated as poor (κ = 0.73). Based on the observed low performances, we question the usefulness of the Q value as a predictor of blasts and whether a blast flag reported by the XE-5000 is sufficient as a criterion for performing a microscopic review.

  2. Synchronized switch harvesting applied to piezoelectric flags

    NASA Astrophysics Data System (ADS)

    Piñeirua, Miguel; Michelin, Sébastien; Vasic, Dejan; Doaré, Olivier

    2016-08-01

    In this article the energy transfer between a flow and a fluttering piezoelectric plate is investigated. In particular, the benefits of the use of a synchronized switch harvesting on inductor (SSHI) circuit are studied. Both wind tunnel experiments and numerical simulations are conducted in order to analyze the influence of the switching process on the dynamics and the efficiency of the system. Numerical simulations consist of a weakly nonlinear model of a plate in axial flow equipped with a single pair of piezoelectric patches, discretized using a Galerkin method where basis functions are the modes of the plate in vacuum. The discretized model is then integrated in time. The results presented in this paper show that a significant improvement of the harvested energy can be obtained using SSHI circuits compared to basic resistive circuits. It is also shown that for strongly coupled systems, the switching process inherent to he SSHI circuit has a significant impact on the dynamics of the flag, which tends to decrease the relative efficiency gain.

  3. Evaluation and optimization of the extended information process unit (E-IPU) validation module integrating the sysmex flag systems and the recommendations of the French-speaking cellular hematology group (GFHC).

    PubMed

    Cornet, Edouard; Mullier, François; Despas, Noemie; Jacqmin, Hugues; Geara, Carole; Boubaya, Marouane; Chatelain, Bernard; Troussard, Xavier

    2016-10-01

    The French-Speaking Cellular Haematology Group (GFHC) recently published criteria for microscopic analysis of a blood smears when a hemogram is requested. In order to evaluate and improve these recommendations using an XN (Sysmex) analyzer, we assessed 31,836 samples categorized into two sub-groups of patients either receiving or not receiving care in the clinical hematology/oncology departments of two university hospitals. By combining the manufacturer's recommendations and the GFHC recommendations, 21.3% of samples had a positive review flag in phase 1 of our study (17,991 samples). In phase 2 (13,845 samples), increasing the immature granulocytes (IG) percentage from 5-10% as a review trigger threshold, and ignoring slides with isolated flags 'PLT HIGH' (thrombocytosis) or 'MCV LOW' (microcytosis) or 'Blast/Abn Lymph and Atypical Lymph' (blast cells/abnormal lymphocytes and atypical lymphocytes) (in the absence of abnormal cells on a previous blood smear within 72 h), enabled us to significantly reduce the number of slides reviewed from 21.3-15.0% (p < 0.0001), without loss of clinical value. This decrease occurred in both sub-groups (hematology 48.7-38.0%, non-hematology 18.3-11.7%, p < 0.0001). In conclusion, the application of the GFHC criteria adapted to XN analyzers has enabled us to optimize the hematology laboratory processes, and thus reduce the production costs and the turnaround time of hemogram results.

  4. COOPER, HERON, AND HEWARD'S APPLIED BEHAVIOR ANALYSIS (2ND ED.): CHECKERED FLAG FOR STUDENTS AND PROFESSORS, YELLOW FLAG FOR THE FIELD

    PubMed Central

    Friman, Patrick C

    2010-01-01

    At last, the field of applied behavior analysis has a beautifully crafted, true textbook that can proudly stand cover to cover and spine to spine beside any of the expensive, imposing, and ornately designed textbooks used by college instructors who teach courses in conventional areas of education or psychology. In this review, I fully laud this development, credit Cooper, Heron, and Heward for making it happen, argue that it signifies a checkered flag for students and professors, and recommend the book for classes in applied behavior analysis everywhere. Subsequently, I review its chapters, each of which could easily stand alone as publications in their own right. Finally, I supply a cautionary note, a yellow flag to accompany the well-earned checkered flag, by pointing out that, as is true with all general textbooks on applied behavior analysis, a major portion of the references involves research on persons who occupy only a tail of the normal distribution. To attain the mainstream role Skinner envisioned and most (if not all) behavior analysts desire, the field will have to increase its focus on persons who reside under the dome of that distribution.

  5. Performance evaluation of the Sysmex XS-1000i automated haematology analyser.

    PubMed

    Ghys, T; Malfait, R; VAN den Bossche, J

    2009-10-01

    The Sysmex XS-1000i is a compact new, fully automated haematology analyser, designed to generate complete blood counts with five-part leucocyte differential. In our study, a Sysmex XS-1000i instrument was evaluated according to Clinical Laboratory Standards Institute (CLSI) and International Council for Standardization in Haematology (ICSH) guidelines. Precision, carry-over and linearity were determined. Using a total of 700 patient samples, results from the Sysmex XS-1000i were compared with those from a Sysmex XE-2100, an Abbott Cell Dyn 4000 and the manual reference leucocyte differential. Using quality control material, total and within-run imprecision was less than 3% except for platelets. The system demonstrated good linearity over the entire reporting range and no carry-over (<0.5%). The Sysmex XS-1000i showed good correlation with XE-2100, CD-4000 and the manual reference leucocyte differential. Overall flagging sensitivity and specificity were 91% and 48%, respectively. In conclusion, the Sysmex XS-1000i demonstrated good analytical performance, is able to generate a complete blood count with five-part differential on low blood volumes and has considerable back-up capacity.

  6. A novel immersed boundary method applied to the inverted flag problem

    NASA Astrophysics Data System (ADS)

    Goza, Andres; Colonius, Timothy

    2015-11-01

    This work uses a 2-D immersed boundary method to study the inverted flag problem, in which a deformable flag is pinned at the trailing edge with its leading edge free to flap. Compared with the canonical flag problem, the inverted configuration more readily undergoes large flapping behavior for a wide range of mass ratios, making it promising in the field of flow-energy harvesting. A previous study identified several flapping modes as a function of dimensionless mass and stiffness ratios (D. Kim et al., J. Fluid Mech., 2013). The present work investigates the role of vortex formation and wake-flag interaction on the different flapping regimes. Simulations are performed using a 2-D immersed boundary method that accurately computes surface stresses imposed on the body by the fluid boundary conditions. Unlike many immersed boundary methods that reconstruct surface stresses from the velocity field, the current method only uses information from the immersed surface, leading to a smaller algebraic system for the fluid-solid coupling. The large flapping behavior of the inverted flag problem highlights the method's ability to simulate flows around bodies undergoing large deformations. This material is based upon work supported by the National Science Foundation Graduate Research Fellowship under Grant No. DGE?1144469.

  7. Analytic errors in Sysmex-generated hematology results in blood from a dog with chronic lymphocytic leukemia.

    PubMed

    Novacco, Marilisa; Martini, Valeria; Grande, Carmen; Comazzi, Stefano

    2015-09-01

    A blood sample from a 14-year-old dog was submitted to the veterinary diagnostic laboratory of the University of Milan for marked leukocytosis with atypical cells. A diagnosis of chronic T-cell lymphocytic leukemia (CLL) was made based on blood smear evaluation and flow cytometric phenotyping. A CBC by Sysmex XT-2000iV revealed a moderate normocytic normochromic anemia. Red blood cells counted by optic flow cytometry (RBC-O) resulted in a higher value than using electrical impedance (RBC-I). The relative reticulocyte count based on RNA content and size was 35.3%, while the manual reticulocyte count was < 1%. The WBC count of 1,562,680 cells/μL was accompanied by a flag. Manual counts for RBC and WBC using the Bürker chamber confirmed the Sysmex impedance results. Finally the manual PCV was lower than HCT by Sysmex. While Sysmex XT can differentiate between RBC and WBC by impedance, even in the face of extreme lymphocytosis due to CLL, RBC-O can be affected by bias, resulting in falsely increased RBC and reticulocyte numbers. Overestimation of RBC-O may be due to incorrect Sysmex classification of leukemic cells or their fragments as reticulocytes. This phenomenon is known as pseudoreticulocytosis and can lead to misinterpretation of regenerative anemia. On the other side PCV can be affected by bias in CLL due to the trapping of RBC in the buffy coat, resulting in a pink hue in the separation area. As HGB concentration is not affected by flow cytometric or other cell-related artifacts it may represent the most reliable variable to assess the degree of anemia in cases of CLL.

  8. Automated Approaches to RFI Flagging

    NASA Astrophysics Data System (ADS)

    Garimella, Karthik; Momjian, Emmanuel

    2017-01-01

    It is known that Radio Frequency Interference (RFI) is a major issue in centimeter wavelength radio astronomy. Radio astronomy software packages include tools to excise RFI; both manual and automated utilizing the visibilities (the uv data). Here we present results on an automated RFI flagging approach that utilizes a uv-grid, which is the intermediate product when converting uv data points to an image. It is a well known fact that any signal that appears widespread in a given domain (e.g., image domain) is compact in the Fourier domain (uv-grid domain), i.e., RFI sources that appear as large scale structures (e.g., stripes) in images can be located and flagged using the uv-grid data set. We developed several automated uv-grid based flagging algorithms to detect and excise RFI. These algorithms will be discussed, and results of applying them to measurement sets will be presented.

  9. 76 FR 35087 - Flag Day and National Flag Week, 2011

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-15

    ... June 15, 2011 Part II The President Proclamation 8689--Flag Day and National Flag Week, 2011 #0; #0; #0... and National Flag Week, 2011 By the President of the United States of America A Proclamation On June... Day, and during National Flag Week, we celebrate the powerful beacon of hope that our flag has...

  10. Analysis of reticulocyte parameters on the Sysmex XE 5000 and LH 750 analyzers in the diagnosis of inefficient erythropoiesis.

    PubMed

    Urrechaga, E; Borque, L; Escanero, J F

    2011-02-01

    The reticulocyte hemoglobin equivalent (Ret He) represents an indirect measure of the functional iron available for erythropoiesis over the previous 2-3 days. Only the analyzers of a single manufacturer, Sysmex (Sysmex Corporation, Kobe, Japan), include Ret He. Red blood cell size factor (RSf) is a new parameter provided by Beckman Coulter, which joins together the volume of the erythrocytes and the volume of reticulocytes. The aims of the study were to investigate the clinical usefulness of RSf in the study of erythropoiesis status and to assess its concordance with Ret He values. Samples from 417 patients were run on both LH 780 (Beckman Coulter) and Sysmex XE 5000 analyzers. Independent samples t-test, Pearson correlation, receiver operating characteristic (ROC) analysis and inter-rater reliability (κ index) were applied. Good correlation between RSf and Ret He was observed, r = 0.8184. Significant differences (P < 0.001) were detected when groups with inefficient erythropoiesis were compared with patients undergoing therapy and healthy subjects. ROC analysis for RSf in the diagnosis of inefficient erythropoiesis, cutoff 91.1 fl, area under curve 0.963, sensitivity 91.7%, specificity 88.5%. Concordance between RSf and Ret He κ = 0.68. RSf and Ret He are suitable parameters for the assessment of erythropoiesis status.

  11. Sysmex UF-1000i performance for screening yeasts in urine.

    PubMed

    Gutiérrez-Fernández, José; Riazzo, Cristina; Sanbonmatsu, Sara; de Dios Luna, Juan; Sorlózano, Antonio; Miranda, Consuelo; Navarro, José María

    2014-04-01

    We tested the capacity of the Sysmex UF-1000i system to detect yeasts in urine by screening a total of 22 132 urine samples received for culture in our microbiology laboratory during 1 year. We also analyzed different dilutions of previously filtered urine inoculated with a strain of Candida albicans. With clinical samples, a single cut-off point of 50 yeast-like cells (YLCs)/μL detected candiduria ≥10 000 colony forming units (CFU)/mL and >100 000 CFU/mL with a sensitivity of 87.3%/95.4%, a specificity of 97%, a negative predictive value of 95.9%, and a positive predictive value of 9.3%/5.7%. With the simulated samples, a linear relationship was observed between the dilution factor and the number of cells detected by UF-1000i. This instrument appears to be able to reliably rule out candiduria of a magnitude of at least 10 000 CFU/mL and facilitate urine sample screening, thereby providing fast results. The Sysmex UF1000i system can be adapted for candiduria screening by the use of an appropriate YLCs/μL cut-off point that takes account of the prevalence of candiduria in the population.

  12. The Ultimate Flag Games.

    ERIC Educational Resources Information Center

    Angel, Kenny; Sutton, Nancy

    This paper describes six Ultimate Flag Games which offer a change from traditional games and sports that are usually geared toward athletically inclined students. These new games, aimed at middle school through college students, allow for success from the least-skilled through the most athletically talented students. Players are ability grouped…

  13. Malaria detection with the Sysmex XE-2100 hematology analyzer using pseudoeosinophilia and abnormal WBC scattergram.

    PubMed

    Huh, Hee Jin; Oh, Gwi Young; Huh, Jung Won; Chae, Seok Lae

    2008-09-01

    Recent investigation using the Sysmex XE-2100 hematology analyzer (Sysmex Corporation, Japan) has demonstrated erroneously high eosinophil counts and abnormal white blood cell (WBC) scattergrams in malaria cases. This study was conducted to assess the diagnostic efficiency of the Sysmex XE-2100 analyzer for malaria. One hundred forty-four patients initially diagnosed with Plasmodium vivax infection, 319 patients with febrile illness, and 24 patients who underwent malaria treatment were analyzed. Atypical features on Sysmex XE-2100 analyzer were categorized as pseudoeosinophilia (a gap of more than 5% in eosinophil counts between the Sysmex XE-2100 analyzer and microscopic examination) and abnormal WBC scattergram. Pseudoeosinophilia or abnormal WBC scattergram were detected in 100 of 144 malaria-positive samples (sensitivity 69.4%, specificity 100%). The samples with pseudoeosinophilia or abnormal WBC scattergrams showed significantly higher parasite counts than the samples without pseudoeosinophilia or an abnormal WBC scattergram (P<0.05). All 24 samples from patients for whom the malaria smear was repeated after malaria treatment was initiated showed a normalized eosinophil count and a normal WBC histogram. In conclusion, attention to differential count and WBC scattergrams provided by the Sysmex XE-2100 would be a valuable tool in malaria detection.

  14. [Erythrocytic parameters Sysmex in a case of severe haemolysis].

    PubMed

    Ferrero-Vacher, Corinne; Senlis, Jean-Éric; Loustaunau, Denis; Aquaronne, Danièle; Jeandel, Pierre-Yves; Sudaka, Isabelle

    2015-01-01

    We are reporting a case of severe haemolytic anemia with cold agglutinins which combines several spurious determinations. It shows the usefulness of the new erythrocytic parameters of the XE 5000 Sysmex, specially: red blood cells with optical count (RBC-O), GR-He (intra-erythocytic hemoglobin) and R-MFV (most frequent volume). Optical red blood cells act as a substitute for red cells count instead of impedance red cells and R-MFV as a substitute for MCV (mean cell volume). The hematocrit (HCT) is corrected thanks to the following formula: HCT=(RBC-O X R- MFV)/1000. Free plasmatic hemoglobin is included in the measure of hemoglobin by the analyzer but is not available for tissue oxygenation. So, hemoglobin (HGB) has to be corrected by the means of GR- He thanks to the following formula: HGB=(GR He x RBC-O)/10.

  15. 78 FR 35101 - Flag Day and National Flag Week, 2013

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-12

    ... Flag Week, 2013 By the President of the United States of America A Proclamation Each June, our Nation... responsibilities we share as citizens. This week, we celebrate that legacy, and we honor the brave men and women... President annually issue a proclamation designating the week in which June 14 occurs as ``National Flag...

  16. 77 FR 35807 - Flag Day and National Flag Week, 2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-15

    ...#0;#0; #0; ] Proclamation 8837 of June 11, 2012 Flag Day and National Flag Week, 2012 By the... against itself.'' This week, we mark nearly one century since that historic proclamation, and more than...), that the President annually issue a proclamation designating the week in which June 14 occurs...

  17. Sysmex XT-2000iV scattergram analysis in a cat with basophilia.

    PubMed

    Stranieri, Angelica; Ferrari, Roberta; Zanzani, Sergio; Rossi, Gabriele

    2016-06-01

    A 13-year-old female Domestic Shorthair cat was presented to the Veterinary Teaching Hospital of the University of Milan for an interscapular mass suspected to be a mesenchymal malignant tumor. A preoperative CBC performed with Sysmex XT-2000iV showed leukocytosis with neutrophilia and eosinophilia. The Sysmex WBC/DIFF scattergram showed an additional, well-separated cluster of events between the neutrophil, eosinophil, and lymphocyte clusters. Blood smear evaluation revealed the presence of a significant number of basophils; thus, it was hypothesized that the additional cluster could represent the basophilic population. A second CBC, 24 days later, showed the same pattern on the WBC/DIFF scattergram in the absence of leukocytosis and neutrophilia. After surgical excision of the mass, a definitive diagnosis of feline injection site sarcoma was made. To the author's knowledge, there are no previous reports about the identification of feline basophils in the WBC/DIFF scattergram of Sysmex XT-2000iV.

  18. First Flag on the Moon

    NASA Video Gallery

    Four months before the launch of Apollo 11, the center director asked for ideas to celebrate the first lunar landing. Jack Kinzler answered with a suggestion to leave an American flag on the surfac...

  19. Chaotic Dynamics of Flags from Recurring Values of Flapping Moment

    NASA Astrophysics Data System (ADS)

    Virot, Emmanuel; Faranda, Davide; Amandolese, Xavier; Hémon, Pascal

    The performance of recently proposed flag-based energy harvesters is strongly limited by the chaotic response of flags to strong winds. From an experimental point of view, the detection of flag chaotic dynamics were scarce, based on the flapping amplitude and the maximal Lyapunov exponent. In practice, tracking the flapping amplitude is difficult and flawed in the large oscillation limit. Also, computing the maximal Lyapunov exponent from time series of limited size requires strong assumptions on the attractor geometry, without getting insurance of their reliability. For bypassing these issues, (1) we use a time series which takes into account the whole dynamics of the flag, by using the flapping moment which integrates its displacements, and (2) we apply an algorithm of detection of chaos based on recurring values in time series.

  20. Evaluation of the Sysmex pocH-1001 haematology analyser in an outdoor oncology service.

    PubMed

    Van Hecke, I; Vanden Bempt, I; Malfait, R; Van Den Bossche, J

    2010-01-01

    Since rapid blood count analysis as near patient testing is expanding, we evaluated the use of a Sysmex pocH-100i compact haematology analyser in an outdoor oncology setting according to the recently published International Council for Standardization in Haematology (ICSH) guidelines. In total, 838 blood samples from oncology patients were analysed by pocH-100i and re-analysed by a high-throughput haematology analyser for comparison (Abbott CD-4000 or Sysmex XE-2100) to evaluate in use imprecision, comparability and vote-outs. Imprecision was less than 5%, except for platelet enumeration in the low range (within-run imprecision 7%). Good comparability was found even for platelet enumeration in the low range (r2 = 0.82). Vote-outs were found in 10.6% of examined samples. In conclusion, the Sysmex pocH-100i demonstrates good imprecision conform with former publications, produces reliable results in normal and in lower ranges comparable to the results of high throughput haematology analysers. In a well controlled management plan the Sysmex pocH-100i is suitable for near patient testing in oncology.

  1. VLA Hosts "Flag Across America"

    NASA Astrophysics Data System (ADS)

    2001-11-01

    The National Radio Astronomy Observatory (NRAO) hosted the runners and support personnel of the "Americans United Flag Across America" run as the transcontinental memorial and fundraising effort came through New Mexico. The flag run arrived at NRAO's Very Large Array (VLA) radio telescope west of Socorro, NM, early in the post-Midnight morning of Monday, November 5, and departed after sunrise that morning en route to the Arizona border. Drivers, runners and support personnel stayed overnight at the VLA. During the night, a "VLA Night Owl Run" kept the flag moving around the VLA area until the westward trek resumed after dawn. The run began Oct. 11, one month after the terrorist attacks on New York and Washington. Organized by employees of American and United Airlines to honor the flight crews lost in those attacks, to show support for U.S. troops and to raise funds to help the victims' families, the run will take an American flag from Boston Logan Airport to Los Angeles International Airport. The Boston-to-Los Angeles trip represents the intended journey of American Flight 11 and United Flight 175, both of which were crashed by terrorists into the World Trade Center. "Our observatory was proud to host this group and honored that they brought this flag through our facility," said Miller Goss, NRAO's director of VLA operations. The runners carried a flag that flew in a U.S. F-16 over Iraq in support of Operation Southern Watch on Oct. 2, and has visited Ground Zero in Manhattan. The flag is scheduled to arrive in Los Angeles on Veterans Day, Nov. 11. The National Radio Astronomy Observatory is a facility of the National Science Foundation, operated under cooperative agreement by Associated Universities, Inc.

  2. 75 FR 34309 - Flag Day and National Flag Week, 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-16

    ... American flag on June 14, 1777, the thirteen stripes alternating red and white, and thirteen white stars in... configuration of stars and stripes has changed over the years it has been flown, its significance and symbolism... after Old Glory was first embraced by our Founders, the Stars and Stripes remain the symbol of...

  3. Current markers of the Athlete Blood Passport do not flag microdose EPO doping.

    PubMed

    Ashenden, Michael; Gough, Clare E; Garnham, Andrew; Gore, Christopher J; Sharpe, Ken

    2011-09-01

    The Athlete Blood Passport is the most recent tool adopted by anti-doping authorities to detect athletes using performance-enhancing drugs such as recombinant human erythropoietin (rhEPO). This strategy relies on detecting abnormal variations in haematological variables caused by doping, against a background of biological and analytical variability. Ten subjects were given twice weekly intravenous injections of rhEPO for up to 12 weeks. Full blood counts were measured using a Sysmex XE-2100 automated haematology analyser, and total haemoglobin mass via a carbon monoxide rebreathing test. The sensitivity of the passport to flag abnormal deviations in blood values was evaluated using dedicated Athlete Blood Passport software. Our treatment regimen elicited a 10% increase in total haemoglobin mass equivalent to approximately two bags of reinfused blood. The passport software did not flag any subjects as being suspicious of doping whilst they were receiving rhEPO. We conclude that it is possible for athletes to use rhEPO without eliciting abnormal changes in the blood variables currently monitored by the Athlete Blood Passport.

  4. 3 CFR 8837 - Proclamation 8837 of June 11, 2012. Flag Day and National Flag Week, 2012

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... pride and all due ceremony those days from Flag Day through Independence Day, also set aside by the... 3 The President 1 2013-01-01 2013-01-01 false Proclamation 8837 of June 11, 2012. Flag Day and... June 11, 2012 Proc. 8837 Flag Day and National Flag Week, 2012By the President of the United States...

  5. The School Flag Movement: Origin and Influence.

    ERIC Educational Resources Information Center

    Sica, Morris G.

    1990-01-01

    Traces the late-nineteenth-century movement to raise the U.S. flag at public schools, Americanize immigrant students, and inspire patriotism through flag exercises and recitation of the Pledge of Allegiance. Identifies political opposition. Relates this history to the June 1989, Supreme Court decision, stating flag burning was protected under the…

  6. Infrared Blobs : Time-dependent Flags

    NASA Astrophysics Data System (ADS)

    McCullough, P. R.; Mack, J.; Dulude, M.; Hilbert, B.

    2014-10-01

    We describe the creation of time-dependent flags for pixels associated with "blobs" on the WFC3 IR detector. We detect the blobs on flat fields obtained by repeated observations of the night side of the Earth. We provide the most complete census of IR blobs' positions, radii, and times of first appearance. In aggregate, a set of 46 blobs, 27 "strong" and 19 "medium" in their effective scattering cross section, affect slightly less than 1% of the pixels of the detector. A second set of 81 "weak" (and typically smaller) blobs affect another 1% of the pixels. In the past, the "blob" flag, bit 9 (i.e. value = 512) in the data quality (DQ) array described in Table 2.5 of the WFC3 Data Handbook (Rajan et al. 2010) has been a static 2-D array; henceforth a set of such arrays, each associated with a "use after" date corresponding to the appearance of one or more new blobs, can be used. We prepared such DQ arrays using the 46 "strong" and "medium" blobs and discuss why we did not include the fainter blobs therein. As an added data product, we create and test a blob flat field that corrects the effects of blobs on extended emission; however, it should not be applied if stellar photometry is the goal.

  7. American Colleges Raise the Flag in Vietnam

    ERIC Educational Resources Information Center

    Overland, Martha Ann

    2009-01-01

    More than 30 years after the U.S. ambassador was airlifted from the embassy rooftop in Saigon with the flag tucked under his arm, a new American flag is going up in the city. This one won't be flying over the embassy. The Stars and Stripes, as well as the Texas state flag, are going up at the Saigon Institute of Technology, the only Vietnamese…

  8. Validation of the Sysmex sp-1000i automated slide preparer-stainer in a clinical laboratory

    PubMed Central

    de Bitencourt, Eberson Damião dos Santos; Voegeli, Carlos Franco; Onzi, Gabriela dos Santos; Boscato, Sara Cardoso; Ghem, Carine; Munhoz, Terezinha

    2013-01-01

    Background The speed and quality of information have become essential items in the release of laboratory reports. The Sysmex®SP1000-I device has been developed to prepare and stain smear slides. However, for a device to be cleared for use in the laboratory routine it must pass through a validation process. Objective To evaluate the performance and reliability of the Sysmex® SP-1000i slide preparer-stainer incorporated into the routine of a hospital laboratory in Porto Alegre. Methods Peripheral blood samples of patients attending the laboratory for ambulatory exams with leukocyte counts between 7000/°L and 12,000/°L were evaluated, independent of gender and age. Two slides were prepared for each sample using the Sysmex® SP-1000i equipment; one of the slides was used to perform quality control tests using the CellaVision® DM96 device, and the other slide was used to compare pre-classification by the same device and the classification performed by a pharmacist-biochemist. Results The results of all the slides used as controls were acceptable according to the quality control test as established by the manufacturer of the device. In the comparison between the automated pre-classification and the classification made by the professional, there was an acceptable variation in the differential counts of leukocytes for 90% of the analyzed slides. Pearson correlation coefficient showed a strong correlation for band neutrophils (r = 0.802; p-value < 0.001), segmented neutrophils (r = 0.963; p-value < 0.001), eosinophils (r = 0.958; p-value < 0.001), lymphocytes (r = 0.985; p-value < 0.001) and atypical lymphocytes (r = 0.866; p-value < 0.001) using both methods. The red blood cell analysis was adequate for all slides analyzed by the equipment and by the professional. Conclusion The new Sysmex®SP1000-i methodology was found to be reliable, fast and safe for the routines of medium and large laboratories, improving the quality of microscopic analysis in complete blood

  9. Vertical Feature Mask Feature Classification Flag Extraction

    Atmospheric Science Data Center

    2013-03-28

    ... flag value. It is written in Interactive Data Language (IDL) as a callable procedure that receives as an argument a 16-bit ... Flag Extraction routine  (5 KB) Interactive Data Language (IDL) is available from  Exelis Visual Information Solutions . ...

  10. [Evaluation of the automated coagulation analyser Sysmex(®) CS-5100 (Siemens)].

    PubMed

    Martin-Toutain, Isabelle; Jobic, Lionel; Mancic, Tessy; Brissard, Alexandre; Ankri, Annick

    2015-01-01

    The Sysmex® CS-5100 is a fully automated multiparameter hemostasis analyzer equipped with a photo-optical clot detection unit, a cap-piercing system and a pre-analytical check screens for interfering substances such as bilirubin, lipids and haemolysis (HIL system). It is designed to perform coagulation tests as well as coagulometric, chromogenic and immunologic assays. The aim of the present study was to evaluate its performance. The intra-assay and inter-assay coefficients of variation (CV) were below 6% for most parameters both in the normal and in the pathological range (exceptions: intra-assay for severe factor VIII deficiency (CV = 7.4%) and for vWFRco (CV = 7.3% and 7.7%); and inter-assay for anti-Xa activity (CV = 8.8%) and vWFRco (9.3% and 11.1%). The measured lower limits of linearity for factor VIII and factor V were satisfactory. No sample or reagent carryover was detected in the conditions of the study. Our results demonstrated that using the Sysmex® CS-5100 analyzer, routine coagulation testing can be performed with satisfactory precision. This automate has the advantage of being connectable to an automation chain.

  11. Fragmented red cells reference range (Sysmex XN(®) automated blood cell counter).

    PubMed

    Lesesve, Jean-François; Daigney, Amandine; Henry, Sylvain; Speyer, Elodie

    2015-01-01

    Fragmented red cells (FRCs) is a new parameter automatedly determined by recent blood cell counters. Their count might be of interest because FRCs are supposed to reflect schistocytes counts measured on a stained peripheral blood smear observed under the microscope. But FRCs depend from the technical procedure used to detect them and thus reference ranges are device-dependent. The XN-9000(®) is one of the last model from Sysmex series. We aimed to establish reference range for FRCs, from 2389 controls. The mean ± SD was 0.32% ± 0.81, the median 0.02% (95% confidence interval ot the mean: 0.29-0.35%). We observed that the percentage of red blood cells with less than 17 pg of hemoglobin content (Hypo-He) was correlated to FRC increase, Hypo-He increase resulting in spurious FRCs majoration. FRCs reference range should be useful for: 1) laboratory staff in order to select which blood smears to check optically; 2) Sysmex company to set-up more optimal rules proposed with the counter (automated making of blood smear).

  12. FLAG-SGH Sedov calculations

    SciTech Connect

    Fung, Jimmy; Schofield, Sam; Shashkov, Mikhail J.

    2012-06-25

    We did not run with a 'cylindrically painted region'. However, we did compute two general variants of the original problem. Refinement studies where a single zone at each level of refinement contains the entire internal energy at t=0 or A 'finite' energy source which has the same physical dimensions as that for the 91 x 46 mesh, but consisting of increasing numbers of zones with refinement. Nominal mesh resolution: 91 x 46. Other mesh resolutions: 181 x 92 and 361 x 184. Note, not identical to the original specification. To maintain symmetry for the 'fixed' energy source, the mesh resolution was adjusted slightly. FLAG Lagrange or full (Eulerian) ALE was used with various options for each simulation. Observation - for either Lagrange or ALE, point or 'fixed' source, calculations converge on density and pressure with mesh resolution, but not energy, (not vorticity either).

  13. Image Artifact Flagging in the Kepler Pipeline

    NASA Astrophysics Data System (ADS)

    Clarke, Bruce; Caldwell, Douglas; Kolodziejczak, Jeffery

    2015-08-01

    Systematic instrument noise in the raw Kepler pixel data includes time-varying crosstalk from the fine guidance sensor (FGS) clock signals, manifestations of drifting moiré pattern as locally correlated nonstationary noise and rolling band artifacts (RBA). The Kepler pipeline module Dynablack produces best fit black level estimates per pixel per cadence by modeling a combination of collateral, FFI, reverse clocked and ARP target data. A search for transit features in the fit residuals identifies spatial regions and time intervals of strong time-varying black level which we identify as RBA. Dynablack produces flags marking these these RBA regions on a per row per cadence basis for several different transit time scales. The Photometric Analysis module (PA) generates per target per cadence data quality flags based on the Dynablack RBA flags which are in turn used by the Data Validation pipeline module (DV) in producing a contamination report associated with each target processed. The Dynablack (per row) RBA flags as well as a proxy for the per target flags produced in PA will be included in the final Kepler data release scheduled to arrive at the MAST in 2016.We detail how the RBA flags are produced in Dynablack, how these are then used to produce the per target quality flags used in DV and discuss why they should be considered when searching for transit signatures in the archived Kepler light curves. Funding for the Kepler Mission has been provided by the NASA Science Mission Directorate.

  14. 78 FR 27982 - U.S. Flag Compliance With MARPOL Annex VI International Energy Efficiency (IEE) Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-13

    ... SECURITY Coast Guard U.S. Flag Compliance With MARPOL Annex VI International Energy Efficiency (IEE... issuance of an International Energy Efficiency Certificate and the preparation of a Ship Energy Efficiency... Energy Efficiency Design Index. These requirements apply to all U.S. flag ships 400 gross tonnage...

  15. Cyber Flag: A Realistic Cyberspace Training Construct

    DTIC Science & Technology

    2008-03-27

    Cyber Flag – initiating and implementing an effective , comprehensive and coordinated training environment in the relatively new, but quickly...that which is effective , comprehensive, and coordinated) is crucial to success in time of war. Red Flag iv provides critical training within the...Force Research Lab’s Human Effectiveness Division for both the support and latitude provided to me in this endeavor. The encouragement and guidance

  16. 49 CFR 393.87 - Warning flags on projecting loads.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 5 2011-10-01 2011-10-01 false Warning flags on projecting loads. 393.87 Section... ACCESSORIES NECESSARY FOR SAFE OPERATION Miscellaneous Parts and Accessories § 393.87 Warning flags on... load marked with red or orange fluorescent warning flags. Each warning flag must be at least 457 mm...

  17. 49 CFR 393.87 - Warning flags on projecting loads.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 5 2013-10-01 2013-10-01 false Warning flags on projecting loads. 393.87 Section... ACCESSORIES NECESSARY FOR SAFE OPERATION Miscellaneous Parts and Accessories § 393.87 Warning flags on... load marked with red or orange fluorescent warning flags. Each warning flag must be at least 457 mm...

  18. 49 CFR 393.87 - Warning flags on projecting loads.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Warning flags on projecting loads. 393.87 Section... ACCESSORIES NECESSARY FOR SAFE OPERATION Miscellaneous Parts and Accessories § 393.87 Warning flags on... load marked with red or orange fluorescent warning flags. Each warning flag must be at least 457 mm...

  19. 49 CFR 393.87 - Warning flags on projecting loads.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 5 2014-10-01 2014-10-01 false Warning flags on projecting loads. 393.87 Section... ACCESSORIES NECESSARY FOR SAFE OPERATION Miscellaneous Parts and Accessories § 393.87 Warning flags on... load marked with red or orange fluorescent warning flags. Each warning flag must be at least 457 mm...

  20. 49 CFR 393.87 - Warning flags on projecting loads.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 5 2012-10-01 2012-10-01 false Warning flags on projecting loads. 393.87 Section... ACCESSORIES NECESSARY FOR SAFE OPERATION Miscellaneous Parts and Accessories § 393.87 Warning flags on... load marked with red or orange fluorescent warning flags. Each warning flag must be at least 457 mm...

  1. Discovering "The Italian Flag" by Fernando Melani (1907-1985)

    NASA Astrophysics Data System (ADS)

    Carlesi, Serena; Bartolozzi, Giovanni; Cucci, Costanza; Marchiafava, Veronica; Picollo, Marcello; La Nasa, Jacopo; Di Girolamo, Francesca; Dilillo, Marialaura; Modugno, Francesca; Degano, Ilaria; Colombini, Maria Perla; Legnaioli, Stefano; Lorenzetti, Giulia; Palleschi, Vincenzo

    2016-11-01

    In the occasion of the celebrations for the 150th anniversary of the founding of Italy (1861-2011), it was decided to analyse the artwork "The Italian Flag" (La Bandiera Italiana) created by the artist Fernando Melani (Pistoia, 1907-1985), one of the precursors of the Poor Art artistic movement in Italy. This project is a follow-up to a previous study which was mainly focused on the pigments and dyes found in his home-studio. The main goal of this paper is to identify a correct diagnostic plan, based on the use of a combination of non-invasive and micro-invasive methodologies, in order to determine the state of preservation and define the best conservation procedures for a contemporary artwork. Visible, infrared and infrared false colour images as well as the Fibre Optic Reflectance Spectroscopy (FORS) technique were applied in situ to analyse The Italian Flag. Laser Induced Breakdown Spectroscopy (LIBS), Fourier Transform Infrared (FT-IR) and micro-Raman spectroscopies, Pyrolysis-Gas Chromatography/Mass Spectroscopy (Py-GC/MS), High Performance Liquid Chromatography with Diode Arrays Detection (HPLC-DAD) and Mass Spectrometric Detection (HPLC-ESI-Q-ToF) were all applied to three small samples detached from the three painted (green-blue, white and red-yellow, respectively) areas of the flag. The combination of the data obtained with all these techniques made possible a comprehensive understanding of both the chemical composition and physical behaviour of the materials used by the artist and supported curators in defining the preventive conservation of this artwork.

  2. Discovering "The Italian Flag" by Fernando Melani (1907-1985).

    PubMed

    Carlesi, Serena; Bartolozzi, Giovanni; Cucci, Costanza; Marchiafava, Veronica; Picollo, Marcello; La Nasa, Jacopo; Di Girolamo, Francesca; Dilillo, Marialaura; Modugno, Francesca; Degano, Ilaria; Colombini, Maria Perla; Legnaioli, Stefano; Lorenzetti, Giulia; Palleschi, Vincenzo

    2016-11-05

    In the occasion of the celebrations for the 150th anniversary of the founding of Italy (1861-2011), it was decided to analyse the artwork "The Italian Flag" (La Bandiera Italiana) created by the artist Fernando Melani (Pistoia, 1907-1985), one of the precursors of the Poor Art artistic movement in Italy. This project is a follow-up to a previous study which was mainly focused on the pigments and dyes found in his home-studio. The main goal of this paper is to identify a correct diagnostic plan, based on the use of a combination of non-invasive and micro-invasive methodologies, in order to determine the state of preservation and define the best conservation procedures for a contemporary artwork. Visible, infrared and infrared false colour images as well as the Fibre Optic Reflectance Spectroscopy (FORS) technique were applied in situ to analyse The Italian Flag. Laser Induced Breakdown Spectroscopy (LIBS), Fourier Transform Infrared (FT-IR) and micro-Raman spectroscopies, Pyrolysis-Gas Chromatography/Mass Spectroscopy (Py-GC/MS), High Performance Liquid Chromatography with Diode Arrays Detection (HPLC-DAD) and Mass Spectrometric Detection (HPLC-ESI-Q-ToF) were all applied to three small samples detached from the three painted (green-blue, white and red-yellow, respectively) areas of the flag. The combination of the data obtained with all these techniques made possible a comprehensive understanding of both the chemical composition and physical behaviour of the materials used by the artist and supported curators in defining the preventive conservation of this artwork.

  3. 38 CFR 3.1607 - Cost of flags.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Section 3.1607 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Burial Benefits § 3.1607 Cost of flags. No reimbursement will be authorized for the cost of a burial flag... burial allowance....

  4. 38 CFR 3.1607 - Cost of flags.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Section 3.1607 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Burial Benefits § 3.1607 Cost of flags. No reimbursement will be authorized for the cost of a burial flag... burial allowance....

  5. 38 CFR 3.1607 - Cost of flags.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Section 3.1607 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Burial Benefits § 3.1607 Cost of flags. No reimbursement will be authorized for the cost of a burial flag... burial allowance....

  6. 38 CFR 3.1607 - Cost of flags.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Section 3.1607 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Burial Benefits § 3.1607 Cost of flags. No reimbursement will be authorized for the cost of a burial flag... burial allowance....

  7. 38 CFR 3.1607 - Cost of flags.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Section 3.1607 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Burial Benefits § 3.1607 Cost of flags. No reimbursement will be authorized for the cost of a burial flag... burial allowance....

  8. Race Discourse and the US Confederate Flag

    ERIC Educational Resources Information Center

    Holyfield, Lori; Moltz, Matthew Ryan; Bradley, Mindy S.

    2009-01-01

    Research reveals that racial hierarchies and "color-blind" racism is maintained through discourse. The current study utilizes exploratory data from focus groups in a predominantly white southern university in the United States to examine race talk, the Confederate Flag, and the construction of southern white identity. Drawing from…

  9. Stability and scalability of piezoelectric flags

    NASA Astrophysics Data System (ADS)

    Wang, Xiaolin; Alben, Silas; Li, Chenyang; Young, Yin Lu

    2016-02-01

    We investigate the effect of piezoelectric material on the flutter speed, vibration mode and frequency, and energy harvesting power and efficiency of a flexible flag in various fluids. We develop a fully coupled fluid-solid-electric model by combining the inviscid vortex sheet model with a linear electro-mechanical coupling model. A resistance only circuit and a resonant resistance-inductance (RL) circuit are considered. For a purely resistive circuit, an increased electro-mechanical coupling factor results in an increased flutter speed, vibration frequency, averaged electric power, and efficiency. A consistent optimal resistance is found that maximizes the flutter speed and the energy harvesting power. For a resonant RL circuit, by tuning the inductance to match the circuit frequency to the flag's vibration frequency, the flutter speed can be greatly decreased, and a larger averaged power and efficiency are obtained. We also consider a model scale setup with several commonly used commercial materials for operating in air and water. Typical ranges of dimensionless parameters are obtained for four types of material that span a wide range of solid density and rigidity values. We find that the resistance only circuit is more effective when the flag is placed in a lighter fluid (e.g., air), while the RL circuit is able to reduce the flutter speed when the flag is placed in a heavier fluid (e.g., water).

  10. Solutions to the Triangular Bicycle Flags Problem

    ERIC Educational Resources Information Center

    Hartweg, Kim

    2005-01-01

    Students in a fifth-grade general education class and a second-grade gifted class participated in the Triangular Bicycle Flags problem. The results indicated that providing students with geometric experiences at the correct van Hiele level is necessary for helping students move from one level of understanding to the next.

  11. The "red flags" rule in health care.

    PubMed

    Gindin, Susan E

    2009-07-01

    Important questions for hospitals to ask regarding the Federal Trade Commission's identity theft "red flags" rule include: What is the compliance deadline? Who must comply? What is required for compliance? What about HIPAA? What are the consequences of failure to comply?

  12. 3 CFR 8993 - Proclamation 8993 of June 7, 2013. Flag Day and National Flag Week, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... States to display the flag during that week. NOW, THEREFORE, I, BARACK OBAMA, President of the United... of the Independence of the United States of America the two hundred and thirty-seventh.BARACK OBAMA...

  13. 10 CFR 1002.22 - Use of distinguishing flag.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Use of distinguishing flag. 1002.22 Section 1002.22 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICIAL SEAL AND DISTINGUISHING FLAG Distinguishing Flag § 1002.22... Department auditoriums, official presentation rooms, hearing rooms, lobbies, public document rooms, and...

  14. 14 CFR 121.595 - Dispatching authority: Flag operations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Dispatching authority: Flag operations. 121... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.595 Dispatching authority: Flag operations. (a) No person may start a flight unless an...

  15. 14 CFR 121.595 - Dispatching authority: Flag operations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Dispatching authority: Flag operations. 121... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.595 Dispatching authority: Flag operations. (a) No person may start a flight unless an...

  16. 14 CFR 121.595 - Dispatching authority: Flag operations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Dispatching authority: Flag operations. 121... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.595 Dispatching authority: Flag operations. (a) No person may start a flight unless an...

  17. 14 CFR 121.595 - Dispatching authority: Flag operations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Dispatching authority: Flag operations. 121... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.595 Dispatching authority: Flag operations. (a) No person may start a flight unless an...

  18. 14 CFR 121.595 - Dispatching authority: Flag operations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Dispatching authority: Flag operations. 121... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.595 Dispatching authority: Flag operations. (a) No person may start a flight unless an...

  19. Comparison of the Sysmex XT-2000iV with microscopic differential counts of canine bone marrow.

    PubMed

    Pernecker, Iris; Bauer, Natali B; Johannes, Sigrid; Ginder, Melanie; Harleman, Johannes H; Moritz, Andreas

    2017-03-01

    Canine bone marrow is frequently assessed in the advanced preclinical research environment. Automated analysis provides time savings and objectivity over the gold standard of microscopic (cytologic) evaluation. We compared the analysis of 90 canine bone marrow samples by the Sysmex XT-2000iV hematology analyzer (Sysmex Corp., Kobe, Japan) with cytologic evaluation. Gates for cell populations were created in the system's WBC/BASO channel. Variables "total nucleated red blood cells" (total_NRBC), "poly- and orthochromatic nucleated red blood cells" (poly_orth_NRBC), "total neutrophils" (total_NEUT), "mature neutrophils" (mature_NEUT), and myeloid-to-erythroid (M:E) ratio were compared with cytologic evaluation. Intra-assay repeatability and total error (TE) were calculated for both methods. Intra-assay repeatability was 0.95-2.48% for the XT-2000iV and 8.32-23.23% for cytology. Observed TE for the automated measurement was 5.16-46.8% and for cytology 22.70-76.74%. Spearman rank correlation was excellent for M:E ratio (0.91) and fair for the other populations (0.65-0.71). Absolute bias for M:E ratio was low (-0.114). A negative absolute bias of -7.71% for the XT-2000iV was found for poly_orth_NRBC, whereas the bias was positive for total_NEUT (7.10%) and mature_NEUT (14.67%). M:E ratio of canine bone marrow samples can be precisely determined using the Sysmex XT-2000iV WBC/BASO channel. Total_NRBC, poly_orth_NRBC, total_NEUT, and mature_NEUT can be estimated rapidly. With distinctly lower coefficient of variation and observed TE compared with cytology, automated measurement provides advantages in terms of standardization, and it is suited to the advanced preclinical research environment where large numbers of samples are investigated.

  20. Modeling Classical Heat Conduction in FLAG

    SciTech Connect

    Ramsey, Scott D.; Hendon, Raymond Cori

    2015-01-12

    The Los Alamos National Laboratory FLAG code contains both electron and ion heat conduction modules; these have been constructed to be directly relevant to user application problems. However, formal code verification of these modules requires quantitative comparison to exact solutions of the underlying mathematical models. A wide variety of exact solutions to the classical heat conduction equation are available for this purpose. This report summarizes efforts involving the representation of the classical heat conduction equation as following from the large electron-ion coupling limit of the electron and ion 3T temperature equations, subject to electron and ion conduction processes. In FLAG, this limiting behavior is quantitatively verified using a simple exact solution of the classical heat conduction equation. For this test problem, both heat conduction modules produce nearly identical spatial electron and ion temperature profiles that converge at slightly less than 2nd order to the corresponding exact solution.

  1. Physicians of the Bear-Flag Republic.

    PubMed

    Bengtsson, Bengt-Ola S

    2016-11-01

    In the mid-nineteenth century, three events coincided to make California the 31st state of the USA: The Mexican-American war of 1846-1848, The Bear Flag Revolt of 1846 and the discovery of gold in 1848. Within a few years a population explosion had occurred and with it came the need for organization of the practice of medicine. This paper outlines the biographies of some physicians who were instrumental in the early years of the Golden State.

  2. Infinite flag varieties and conjugacy theorems

    PubMed Central

    Peterson, Dale H.; Kac, Victor G.

    1983-01-01

    We study the orbit of a highest-weight vector in an integrable highest-weight module of the group G associated to a Kac-Moody algebra [unk](A). We obtain applications to the geometric structure of the associated flag varieties and to the algebraic structure of [unk](A). In particular, we prove conjugacy theorems for Cartan and Borel subalgebras of [unk](A), so that the Cartan matrix A is an invariant of [unk](A). PMID:16593298

  3. Establishment of Age- and Gender-Specific Reference Ranges for 36 Routine and 57 Cell Population Data Items in a New Automated Blood Cell Analyzer, Sysmex XN-2000

    PubMed Central

    Park, Sang Hyuk; Lee, Bo-Ra; Kim, Mi-Jeong; Han, Min-Young; Cho, Young-Uk; Jang, Seongsoo

    2016-01-01

    We established age- and gender-specific reference ranges for the 36 routine complete blood cell (CBC) and 57 cell population data (CPD) items in the Sysmex XN-2000 (Sysmex, Japan). In total, 280 peripheral blood samples were obtained from an equal number of healthy adults. Values for 36 routine items and 57 CPD items were obtained for each sample, and the results were categorized into six subgroups (N>39 in each subgroup) according to patient age (20-40, 41-60, and >60 yr) and gender (male and female), and compared with respect to age and gender differences. The majority of data items (22 of 36 routine CBC items and 44 of 57 CPD items) exhibited significant differences (P≤0.05) in their results with respect to age or gender, and several red cell-, lymphocyte-, and platelet-related data tended to decrease in women or older adults. These results provide a basis for establishing age- and gender-specific reference ranges for routine and CPD items in Sysmex XN-2000. Furthermore, these reference ranges could be used to determine clinical significance for new items of Sysmex XN-2000 in further studies. PMID:26915613

  4. Establishment of Age- and Gender-Specific Reference Ranges for 36 Routine and 57 Cell Population Data Items in a New Automated Blood Cell Analyzer, Sysmex XN-2000.

    PubMed

    Park, Sang Hyuk; Park, Chan Jeoung; Lee, Bo Ra; Kim, Mi Jeong; Han, Min Young; Cho, Young Uk; Jang, Seongsoo

    2016-05-01

    We established age- and gender-specific reference ranges for the 36 routine complete blood cell (CBC) and 57 cell population data (CPD) items in the Sysmex XN-2000 (Sysmex, Japan). In total, 280 peripheral blood samples were obtained from an equal number of healthy adults. Values for 36 routine items and 57 CPD items were obtained for each sample, and the results were categorized into six subgroups (N>39 in each subgroup) according to patient age (20-40, 41-60, and >60 yr) and gender (male and female), and compared with respect to age and gender differences. The majority of data items (22 of 36 routine CBC items and 44 of 57 CPD items) exhibited significant differences (P≤0.05) in their results with respect to age or gender, and several red cell-, lymphocyte-, and platelet-related data tended to decrease in women or older adults. These results provide a basis for establishing age- and gender-specific reference ranges for routine and CPD items in Sysmex XN-2000. Furthermore, these reference ranges could be used to determine clinical significance for new items of Sysmex XN-2000 in further studies.

  5. Red flag imaging techniques in Barrett's esophagus.

    PubMed

    Saxena, Payal; Canto, Marcia Irene

    2013-07-01

    The key to detection and treatment of early neoplasia in Barrett's esophagus (BE) is thorough and careful inspection of the Barrett's segment. The greatest role for red flag techniques is to help identify neoplastic lesions for targeted biopsy and therapy. High-definition white light endoscopy (HD-WLE) can potentially improve endoscopic imaging of BE compared with standard endoscopy, but little scientific evidence supports this. The addition of autofluorescence imaging to HD-WLE and narrow band imaging increases sensitivity and the false-positive rate without significantly improving overall detection of BE-related neoplasia.

  6. 3 CFR 8391 - Proclamation 8391 of June 11, 2009. Flag Day and National Flag Week, 2009

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... America A Proclamation In the midst of a war for our Nation's independence, on June 14, 1777, the Second... toward equality and justice for all. Our flag's journey has been long. It has seen our Nation through war... the Civil Rights Movement, determined protesters on the streets of Selma, Alabama, proudly...

  7. The Flag of the United States and State Flags, Seals & Mottoes.

    ERIC Educational Resources Information Center

    Kennon, Donald R.; Kerr, Mary Lee

    A detailed and descriptive narrative is presented about the U.S. flag's history, development, symbolic meaning, and overall importance. Information about the U.S. seal and how it identifies what the United States stands for as a nation is given. A motto is defined as a word or phrase that expresses one's principles, religious, moral, or patriotic…

  8. Interaction between two side-by-side inverted flags

    NASA Astrophysics Data System (ADS)

    Huertas-Cerdeira, Cecilia; Fan, Boyu; Barizien, Antoine; Gharib, Morteza

    2015-11-01

    The inverted flag instability occurs when an elastic plate that is free at its leading edge and clamped at its trailing edge is subjected to an axial wind. The oscillating motion that follows has received recent attention. However, previous studies have focused on the dynamics of a single flag even though these are rarely found isolated in natural phenomena, such as the fluttering of leaves in the wind. The interaction between two side-by-side inverted flags has been investigated, analyzing the effects of the distance between flags and the wind speed. Both in-phase and anti-phase coupling have been observed for different ranges of these parameters.

  9. 18. NORTH TOWER, PORTE COCHERE & FLAG TOWER, LOOKING SOUTHWEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. NORTH TOWER, PORTE COCHERE & FLAG TOWER, LOOKING SOUTHWEST BY WEST - Smithsonian Institution Building, 1000 Jefferson Drive, between Ninth & Twelfth Streets, Southwest, Washington, District of Columbia, DC

  10. 19. NORTH TOWER, PORTE COCHERE & FLAG TOWER, LOOKING SOUTHWEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. NORTH TOWER, PORTE COCHERE & FLAG TOWER, LOOKING SOUTHWEST - Smithsonian Institution Building, 1000 Jefferson Drive, between Ninth & Twelfth Streets, Southwest, Washington, District of Columbia, DC

  11. 36. FLAG TOWER CLOCK ZONE FROM SOUTH TOWER ROOF, LOOKING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    36. FLAG TOWER CLOCK ZONE FROM SOUTH TOWER ROOF, LOOKING NORTH - Smithsonian Institution Building, 1000 Jefferson Drive, between Ninth & Twelfth Streets, Southwest, Washington, District of Columbia, DC

  12. [Influence of reagent storage in Sysmex CA7000 for different time on 4 test RESULTS: of the plasma coagulation].

    PubMed

    Chen, Tong-Qing; Li, Zhen-Xing

    2014-12-01

    The purpose of this study was to investigate the influence of blood coagulation reagents stored for different time on test results of the specimens prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT) and fibrinogen (Fib). A total of 21 patient plasma specimens was taken and measured for homeostasis by Sysmex CA7000 automated blood coagulation analyzer and supporting reagent. The PT, APTT, TT and Fib of specimens were measured with the reagents stored in Sysmex CA7000 for different time. The differences of PT, APTT, TT and Fib were analyzed between values measured of the reagents stored for 0 hour and different time (TS:12, 24, 36,48, 60, 72 h; DA:24, 48, 72, 96, 120 h; TT:2, 4, 6, 8, 10, 12 h; TR:4, 8, 12, 16, 20, 24 h; OVB:1, 2, 3, 4, 5 ,6 h), respectively. The results showed that when coagulation reagent TS were stored for more than 48 h , DA 96 h, TT 10 h, TR 16 h and OVB 4 h, the values of PT, APTT, TT and Fib of samples were statistically different from the values measured with fresh coagulation reagent (P < 0.01), respectively. Compared 0 h with TS stored for 48-72, DA 96-120, TT 10-12, TR 16-24 and OVB 4-6 h, the percentage difference of PT, APTT, TT and Fib is in -2.6% ∼ 10.8%, -3.44% ∼ 4.8%, -3.9% ∼ 5.52%, -10.8% ∼ 3.3% and -17.2% ∼ 0.5%, the PT and Fib changes were more significant. Accordingly, the result of PT, APTT and TT had a uptrend as the reagent stored in Sysmex CA7000 analyzer for a long time, while Fib downtrend. It is concluded that the reagents showed be timely replaced when the plasma coagulation test is performed so as to obtain accurate results of examination.

  13. Where no flag has gone before: Political and technical aspects of placing a flag on the Moon

    NASA Technical Reports Server (NTRS)

    Platoff, Anne M.

    1993-01-01

    The flag on the Moon represents an important event in vexillological history. The political and technical aspects of placing a flag on the Moon, focusing on the first Moon landing, is examined. During their historic extravehicular activity, the Apollo 11 crew planted the flag of the United States on the lunar surface. This flag-raising was strictly a symbolic activity, as the United Nations Treaty on Outer Space precluded any territorial claim. Nevertheless, there were domestic and international debates over the appropriateness of the event. Congress amended the agency's appropriations bill to prevent the National Aeronautics and Space Administration (NASA) from placing flags of other nations, or those of international associations, on the Moon during missions funded solely by the United States. Like any activity in space exploration, the Apollo flag-raising also provided NASA engineers with an interesting technical challenge. They designed a flagpole with a horizontal bar allowing the flag to 'fly' without the benefit of wind to overcome the effects of the Moon's lack of an atmosphere. Other factors considered in the design were weight, heat resistance, and ease of assembly by astronauts whose space suits restricted their range of movement and ability to grasp items. As NASA plans a return to the Moon and an expedition to Mars, we will likely see flags continue to go 'where no flag has gone before'.

  14. Differential signalling of NH2-terminal flag-labelled thrombopoietin receptor activated by TPO or anti-FLAG antibodies.

    PubMed

    Millot, Gaël A; Vainchenker, William; Duménil, Dominique; Svinarchuk, Fédor

    2004-03-01

    In this report, we compared activation of NH2-terminal FLAG-labelled thrombopoietin receptor (Mpl) by anti-FLAG antibodies and by thrombopoietin (TPO). We found that anti-FLAG monoclonal antibodies M1 dimerize FLAG-labelled receptor and trigger proliferation of BaF3/FLAG-Mpl cells. In UT7/FLAG-Mpl cells, activation of the FLAG-Mpl receptor by low TPO concentrations triggered proliferation, while high concentrations triggered differentiation. Activation of FLAG-Mpl receptors in these cells by all tested concentrations of M1 antibodies induced proliferation but not differentiation. Low TPO concentrations induced similar to M1 antibodies level of Jak2, Stat3, Stat5 and Akt phosphorylation. In contrast, only TPO and not M1 antibodies activated Erks phosphorylation. Since the anti-FLAG antibodies do not react with the TPO binding site of the receptor, we hypothesize that they can trigger a distinct signal by dimerizing Mpl in a manner different from that induced by TPO.

  15. Diagnosing feline infectious peritonitis using the Sysmex XT-2000iV based on frozen supernatants from cavitary effusions.

    PubMed

    Stranieri, Angelica; Paltrinieri, Saverio; Giordano, Alessia

    2017-02-01

    The delta total nucleated cells (ΔTNC) measurement with the Sysmex XT-2000iV (Sysmex Europe, Norderstedt, Germany) has high diagnostic accuracy on effusions in feline infectious peritonitis (FIP) cases, but the test can be performed only on fresh samples. We evaluated whether supernatants from effusions retain the ability to induce cell clumping and assessed the diagnostic accuracy of this modified ΔTNC method. Effusions were collected from FIP cats ( n = 19) and from cats with other diseases ( n = 15). ΔTNC was measured on fresh samples and on frozen-thawed supernatants after the addition of feline blood at 1:10 dilution. Diagnostic accuracy was assessed at the cutoffs of suggestive of FIP (ΔTNC = 1.7) and consistent with FIP (ΔTNC = 3.4). The influence of the protein content, number of added cells, and magnitude of dilution were also investigated. Specificity and positive predictive value were 100% for both the methods. Sensitivity and negative predictive value were higher for the modified ΔTNC (84.2% and 83.3%, respectively, at the cutoff of 1.7; 78.9% and 78.9%, respectively, at the cutoff of 3.4) than for the ΔTNC on fresh samples (78.6% and 81.3%, respectively, at the cutoff of 1.7; 57.1% and 68.4%, respectively, at the cutoff of 3.4). Protein content, total cell count of the added blood, and magnitude of dilutions did not influence the results. Supernatants of frozen effusions from FIP cats retain the ability to induce cell clumping, thus the modified ΔTNC measurement is a reliable tool to diagnose FIP on samples that cannot be analyzed immediately.

  16. 10 CFR 1.55 - Establishment of official NRC flag.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Establishment of official NRC flag. 1.55 Section 1.55 Energy NUCLEAR REGULATORY COMMISSION STATEMENT OF ORGANIZATION AND GENERAL INFORMATION NRC Seal and Flag... dark blue field with a gold fringe....

  17. FIRE! A Red Flag Tap in Reclaiming Intervention

    ERIC Educational Resources Information Center

    Bodnar, Brian

    2007-01-01

    "Red Flag Interventions" address problems which are imported from elsewhere and acted out towards persons who are in effect innocent bystanders. This is commonly seen as students "carry in" problems from the home or street to school, or they "carry over" conflicts from one class to the next. A third variation of Red Flag intervention is when a…

  18. Continued Legal Developments on the School Flag Movement.

    ERIC Educational Resources Information Center

    Knowles, Trudy

    1992-01-01

    Traces the legal history of the school flag movement and efforts of religious groups to have the mandatory salute abolished. Suggests that schools must educate students for true citizenship and what it means to live in a democracy. Argues that the flag should be a symbol of freedom rather than the object of empty pledges. (DK)

  19. Effects of morphology on the flapping dynamics of inverted flags

    NASA Astrophysics Data System (ADS)

    Fan, Boyu; Cosse, Julia; Sader, John; Gharib, Morteza

    2014-11-01

    The behavior of inverted flags has received recent attention in the study of the interaction of flexible bodies with fluid flows. It has implications in a variety of natural phenomena, such as the fluttering of leaves in the wind. As opposed to a conventional flag, defined by a fixed leading edge and a free trailing edge, an inverted flag has a free leading edge and a fixed trailing edge. The reversed flow orientation of inverted flags has led to a surprising observation. Over a narrow range of wind speeds, they exhibit a large-amplitude flapping motion that is not present in their conventional counterparts. Our study experimentally investigates the effects of flag morphology on the flapping behavior of inverted flags. Different flags ranging from rectangles to triangles are studied in a wind tunnel to assess the underlying parameters that govern their dynamics. We observe a significant shift in the limit-cycle flapping mode that is a function of flag shape parameters. This research is supported by the Lester Lees Aeronautics Summer Undergraduate Research Fellowship and the Gordon and Betty Moore Foundation.

  20. A Comparison of Injuries between Flag and Touch Football.

    ERIC Educational Resources Information Center

    Martin, Stephen L.

    This study was designed to determine whether fewer and less serious injuries result from participation in touch football as compared with flag football. A survey was taken of 30 flag football games and 30 touch football games and the incidence of injuries was recorded on a checklist. Results of the survey suggest the following: (a) intramural or…

  1. 14 CFR 121.661 - Initial approach altitude: Flag operations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Initial approach altitude: Flag operations... § 121.661 Initial approach altitude: Flag operations. When making an initial approach to a radio navigation facility under IFR, no person may descend below the pertinent minimum altitude for...

  2. 14 CFR 121.661 - Initial approach altitude: Flag operations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Initial approach altitude: Flag operations... § 121.661 Initial approach altitude: Flag operations. When making an initial approach to a radio navigation facility under IFR, no person may descend below the pertinent minimum altitude for...

  3. 14 CFR 121.661 - Initial approach altitude: Flag operations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Initial approach altitude: Flag operations... § 121.661 Initial approach altitude: Flag operations. When making an initial approach to a radio navigation facility under IFR, no person may descend below the pertinent minimum altitude for...

  4. 14 CFR 121.661 - Initial approach altitude: Flag operations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Initial approach altitude: Flag operations... § 121.661 Initial approach altitude: Flag operations. When making an initial approach to a radio navigation facility under IFR, no person may descend below the pertinent minimum altitude for...

  5. 14 CFR 121.661 - Initial approach altitude: Flag operations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Initial approach altitude: Flag operations... § 121.661 Initial approach altitude: Flag operations. When making an initial approach to a radio navigation facility under IFR, no person may descend below the pertinent minimum altitude for...

  6. 78 FR 17931 - Information Collection; Open Government Citizen Engagement Ratings, Rankings, and Flagging

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-25

    ... ADMINISTRATION Information Collection; Open Government Citizen Engagement Ratings, Rankings, and Flagging AGENCY... regarding open government citizen engagement ratings, rankings, and flagging. DATES: Comments must be...- 0288, Open Government Citizen Engagement Ratings, Rankings, and Flagging, by any of the...

  7. Transcriptome phase distribution analysis reveals diurnal regulated biological processes and key pathways in rice flag leaves and seedling leaves.

    PubMed

    Xu, Wenying; Yang, Rendong; Li, Meina; Xing, Zhuo; Yang, Wenqiang; Chen, Guang; Guo, Han; Gong, Xiaojie; Du, Zhou; Zhang, Zhenhai; Hu, Xingming; Wang, Dong; Qian, Qian; Wang, Tai; Su, Zhen; Xue, Yongbiao

    2011-03-02

    Plant diurnal oscillation is a 24-hour period based variation. The correlation between diurnal genes and biological pathways was widely revealed by microarray analysis in different species. Rice (Oryza sativa) is the major food staple for about half of the world's population. The rice flag leaf is essential in providing photosynthates to the grain filling. However, there is still no comprehensive view about the diurnal transcriptome for rice leaves. In this study, we applied rice microarray to monitor the rhythmically expressed genes in rice seedling and flag leaves. We developed a new computational analysis approach and identified 6,266 (10.96%) diurnal probe sets in seedling leaves, 13,773 (24.08%) diurnal probe sets in flag leaves. About 65% of overall transcription factors were identified as flag leaf preferred. In seedling leaves, the peak of phase distribution was from 2:00am to 4:00am, whereas in flag leaves, the peak was from 8:00pm to 2:00am. The diurnal phase distribution analysis of gene ontology (GO) and cis-element enrichment indicated that, some important processes were waken by the light, such as photosynthesis and abiotic stimulus, while some genes related to the nuclear and ribosome involved processes were active mostly during the switch time of light to dark. The starch and sucrose metabolism pathway genes also showed diurnal phase. We conducted comparison analysis between Arabidopsis and rice leaf transcriptome throughout the diurnal cycle. In summary, our analysis approach is feasible for relatively unbiased identification of diurnal transcripts, efficiently detecting some special periodic patterns with non-sinusoidal periodic patterns. Compared to the rice flag leaves, the gene transcription levels of seedling leaves were relatively limited to the diurnal rhythm. Our comprehensive microarray analysis of seedling and flag leaves of rice provided an overview of the rice diurnal transcriptome and indicated some diurnal regulated biological

  8. Structure of anti-FLAG M2 Fab domain and its use in the stabilization of engineered membrane proteins

    SciTech Connect

    Roosild, Tarmo P.; Castronovo, Samantha; Choe, Senyon

    2006-09-01

    The X-ray crystallographic analysis of anti-FLAG M2 Fab is reported and the implications of the structure on FLAG epitope binding are described as a first step in the development of a tool for the structural and biophysical study of membrane proteins. The inherent difficulties of stabilizing detergent-solubilized integral membrane proteins for biophysical or structural analysis demand the development of new methodologies to improve success rates. One proven strategy is the use of antibody fragments to increase the ‘soluble’ portion of any membrane protein, but this approach is limited by the difficulties and expense associated with producing monoclonal antibodies to an appropriate exposed epitope on the target protein. Here, the stabilization of a detergent-solubilized K{sup +} channel protein, KvPae, by engineering a FLAG-binding epitope into a known loop region of the protein and creating a complex with Fab fragments from commercially available anti-FLAG M2 monoclonal antibodies is reported. Although well diffracting crystals of the complex have not yet been obtained, during the course of crystallization trials the structure of the anti-FLAG M2 Fab domain was solved to 1.86 Å resolution. This structure, which should aid future structure-determination efforts using this approach by facilitating molecular-replacement phasing, reveals that the binding pocket appears to be specific only for the first four amino acids of the traditional FLAG epitope, namely DYKD. Thus, the use of antibody fragments for improving the stability of target proteins can be rapidly applied to the study of membrane-protein structure by placing the short DKYD motif within a predicted peripheral loop of that protein and utilizing commercially available anti-FLAG M2 antibody fragments.

  9. Flapping dynamics of an inverted flag in a uniform flow

    NASA Astrophysics Data System (ADS)

    Ryu, Jaeha; Park, Sung Goon; Kim, Boyoung; Sung, Hyung Jin

    2015-11-01

    Much research in recent years has focused on the flow dynamics of flexible structures in a uniform flow and particularly on the flow dynamics related to energy harvesting systems. An energy harvesting system comprising piezoelectric patches attached to the surface of a flexible structure can convert the energy stored in solid deformations into an electric current that powers a purely resistive output circuit. Recently, an inverted flag which has the freely moving leading edge and the clamped trailing edge was suggested. The inverted flag improved the amount of strain energy that was converted into the flag deformations from the surrounding fluid. In this study, the flapping dynamics of an inverted flag in a uniform flow were simulated using the immersed boundary method. The flapping dynamics of and vortical structures around the inverted flag were examined in terms of the bending rigidity and the Reynolds number. The strain energy of the inverted flag and the proportion of the strain energy of the inverted flag to the kinetic energy of the flow were considered as an indicator of the energy harvesting system efficiency.

  10. Self-propulsion of a heaving and pitching flexible flag

    NASA Astrophysics Data System (ADS)

    Kim, Boyoung; Park, Sung Goon; Sung, Hyung Jin

    2015-11-01

    Flapping motions of flexible flags are widespread in nature. Birds, fish, and insects use their wings, fins, or bodies to stay afloat and to advance forward in the surrounding fluids. In the present study, a self-propelled flexible flag with heaving and pitching motions in a quiescent flow has been simulated by using the immersed boundary method. The flexible flag can move freely in the horizontal direction and the body of the flexible flag moves passively along the head. The motion of the head of the flag was described as a harmonic heaving oscillation in the vertical direction. The motion of the angle of the head was described as a harmonic oscillation with a moving clamped condition for the heaving and pitching flag. The cruising speed and the swimming efficiency of the self-propelled flag were determined as functions of the bending coefficient (γ) , the heaving amplitude (Ah) , the pitching amplitude (Ap) , the heaving frequency (St), and the phase difference (Δϕ) between Ah and Ap. We conducted a parametric study on the optimized the cruising speed and the swimming efficiency with respect to γ, St, Ah, Ap, and Δϕ

  11. Interior detail of platform in main hall, with desk, flag, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior detail of platform in main hall, with desk, flag, and banners, facing south - International Longshoremen's & Warehousemen's Union Hall, Naval Civil Engineering Laboratory, Port Hueneme Road, Port Hueneme, Ventura County, CA

  12. View of the north tower porte cochere and flag tower, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of the north tower porte cochere and flag tower, looking southwest (duplicate of HABS No. DC-141-19) - Smithsonian Institution Building, 1000 Jefferson Drive, between Ninth & Twelfth Streets, Southwest, Washington, District of Columbia, DC

  13. SOUTH ELEVATION. THE DWELLING, FLAG TOWER, AND HAZARDOUS MATERIAL STORAGE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    SOUTH ELEVATION. THE DWELLING, FLAG TOWER, AND HAZARDOUS MATERIAL STORAGE SHED ARE VISIBLE IN THE BACKGROUND. - U.S. Coast Guard Lake Worth Inlet Station, Boathouse, Peanut Island, Riviera Beach, Palm Beach County, FL

  14. WEST ELEVATION. DWELLING AND FLAG TOWER ARE IN THE DISTANCE. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    WEST ELEVATION. DWELLING AND FLAG TOWER ARE IN THE DISTANCE. HAZARDOUS MATERIAL STORAGE SHED IS IN THE FOREGROUND. - U.S. Coast Guard Lake Worth Inlet Station, Boathouse, Peanut Island, Riviera Beach, Palm Beach County, FL

  15. 46 CFR 282.10 - Basis for determining foreign-flag competition.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Basis for determining foreign-flag competition. 282.10... SERVICES IN THE FOREIGN COMMERCE OF THE UNITED STATES Foreign-Flag Competition § 282.10 Basis for determining foreign-flag competition. The foreign-flag competition shall form the basis for determining...

  16. 46 CFR 282.10 - Basis for determining foreign-flag competition.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Basis for determining foreign-flag competition. 282.10... SERVICES IN THE FOREIGN COMMERCE OF THE UNITED STATES Foreign-Flag Competition § 282.10 Basis for determining foreign-flag competition. The foreign-flag competition shall form the basis for determining...

  17. Efficiency of flagging and dragging for tick collection.

    PubMed

    Dantas-Torres, Filipe; Lia, Riccardo Paolo; Capelli, Gioia; Otranto, Domenico

    2013-09-01

    It is acknowledged that data from field studies on tick ecology might be biased by collection methods, but actually comparative studies are still limited. Herein we assessed whether the efficiency of flagging and dragging varies according to tick developmental stage, species, season and habitat. Ticks were collected in three sites bordered by an oak forest. The abundance of ticks collected by each collection method varied according to tick species, developmental stage, season, and habitat. Flagging was in general more efficient in collecting adult ticks, especially in spring and winter. Females were more frequently collected by flagging in the meadow and grassland habitats and males in the man-made trail. Flagging collected significantly more adults of Dermacentor marginatus, Hyalomma marginatum, Haemaphysalis inermis and Ixodes ricinus. Flagging was more efficient in collecting D. marginatus and I. ricinus in spring, and H. inermis and I. ricinus females in both spring and winter. In summer and autumn tick abundances were generally similar, with the exception of D. marginatus female in autumn. Flagging was more efficient in collecting D. marginatus adults in the meadow habitat and in the man-made trail, and I. ricinus adults in the meadow and grassland habitats. Dragging was more efficient in grassland for R. turanicus. Our results suggest that variations in terms of collection method performance are associated to factors linked to tick behaviour, habitat characteristics, and climate. Field studies employing these collection methods should take this into account to avoid misleading conclusions about tick population dynamics and tick-borne pathogen transmission risk.

  18. Clinical significance of cell population data (CPD) on Sysmex XN-9000 in septic patients with our without liver impairment

    PubMed Central

    Seghezzi, Michela; Vavassori, Mauro; Dominoni, Paola; Apassiti Esposito, Sara; Manenti, Barbara; Mecca, Tommaso; Marchesi, Gianmariano; Castellucci, Enrico; Azzarà, Giovanna; Ottomano, Cosimo; Lippi, Giuseppe

    2016-01-01

    Background This study evaluated the clinical significance of cell population data (CPD) parameters obtained on Sysmex XN-9000 in septic patients admitted to intensive care unit (ICU) and stratified according to liver function. Methods The study population consisted in 84 patients, 44 of whom did not develop sepsis (NS), whereas the remaining 40 developed sepsis (SE) (n=24) or septic shock (SS) (n=16). Two hundred ostensibly healthy blood donors [healthy subjects (HS)], undergoing routine blood testing before a regular blood donation, were studied. Results Except for neutrophils and lymphocytes cell size (NE-FCS and LY-Z), all other CPD values were significantly different in ICU patients compared to HS. Neutrophils and monocytes fluorescence intensity (NE-SFL and MO-X) values were significantly higher in SS compared to sepsis and not develop sepsis patients. The value of many parameters was also different according to liver function. Overall, MO-X and neutrophils fluorescence intensity (NE-SFL) exhibited the best performance for diagnosing sepsis in all patients (AUC, 0.75 and 0.72), as well as in those with (AUC, 0.95 and 0.89) or without (AUC, 0.72 for both) liver impairment. These parameters were also significantly correlated with Sequential Organ Failure Assessment (SOFA) score. Conclusions This study suggested that some novel CPD parameters (namely NE-SFL and MO-X) may provide useful information for diagnosis and management of sepsis. PMID:27942509

  19. High explosive programmed burn in the FLAG code

    SciTech Connect

    Mandell, D.; Burton, D.; Lund, C.

    1998-02-01

    The models used to calculate the programmed burn high-explosive lighting times for two- and three-dimensions in the FLAG code are described. FLAG uses an unstructured polyhedra grid. The calculations were compared to exact solutions for a square in two dimensions and for a cube in three dimensions. The maximum error was 3.95 percent in two dimensions and 4.84 percent in three dimensions. The high explosive lighting time model described has the advantage that only one cell at a time needs to be considered.

  20. Development of a validation algorithm for 'present on admission' flagging

    PubMed Central

    2009-01-01

    Background The use of routine hospital data for understanding patterns of adverse outcomes has been limited in the past by the fact that pre-existing and post-admission conditions have been indistinguishable. The use of a 'Present on Admission' (or POA) indicator to distinguish pre-existing or co-morbid conditions from those arising during the episode of care has been advocated in the US for many years as a tool to support quality assurance activities and improve the accuracy of risk adjustment methodologies. The USA, Australia and Canada now all assign a flag to indicate the timing of onset of diagnoses. For quality improvement purposes, it is the 'not-POA' diagnoses (that is, those acquired in hospital) that are of interest. Methods Our objective was to develop an algorithm for assessing the validity of assignment of 'not-POA' flags. We undertook expert review of the International Classification of Diseases, 10th Revision, Australian Modification (ICD-10-AM) to identify conditions that could not be plausibly hospital-acquired. The resulting computer algorithm was tested against all diagnoses flagged as complications in the Victorian (Australia) Admitted Episodes Dataset, 2005/06. Measures reported include rates of appropriate assignment of the new Australian 'Condition Onset' flag by ICD chapter, and patterns of invalid flagging. Results Of 18,418 diagnosis codes reviewed, 93.4% (n = 17,195) reflected agreement on status for flagging by at least 2 of 3 reviewers (including 64.4% unanimous agreement; Fleiss' Kappa: 0.61). In tests of the new algorithm, 96.14% of all hospital-acquired diagnosis codes flagged were found to be valid in the Victorian records analysed. A lower proportion of individual codes was judged to be acceptably flagged (76.2%), but this reflected a high proportion of codes used <5 times in the data set (789/1035 invalid codes). Conclusion An indicator variable about the timing of occurrence of diagnoses can greatly expand the use of routinely

  1. 46 CFR 381.5 - Fix American-flag tonnage first.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... preference cargoes required by that Act and the Food Security Act of 1985 to be shipped on U.S.-flag vessels... Maritime Administration, that (a) U.S.-flag vessels are not available at fair and reasonable rates for...

  2. 46 CFR 381.5 - Fix American-flag tonnage first.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... preference cargoes required by that Act and the Food Security Act of 1985 to be shipped on U.S.-flag vessels... Maritime Administration, that (a) U.S.-flag vessels are not available at fair and reasonable rates for...

  3. 46 CFR 381.5 - Fix American-flag tonnage first.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... preference cargoes required by that Act and the Food Security Act of 1985 to be shipped on U.S.-flag vessels... Maritime Administration, that (a) U.S.-flag vessels are not available at fair and reasonable rates for...

  4. Tips to Increase Girls' Participation in Flag Football Units

    ERIC Educational Resources Information Center

    Hannon, James C.; Ratliffe, Thomas

    2006-01-01

    Despite the apparent popularity of flag football as an activity in physical education class and football as an after-school offering for girls, studies related to gender stereotyping of sports have found overwhelming evidence indicating that football is perceived as a masculine activity among males and females in primary school, secondary school,…

  5. 10 CFR 1002.21 - Description of distinguishing flag.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... shall be of rayon banner, measure 4′4″ on hoist by 5′6″ on the fly, exclusive of heading and hems, and be fringed on three edges with yellow rayon fringe, 21/2″ wide. (2) The outdoor flag shall be...

  6. 10 CFR 1002.21 - Description of distinguishing flag.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... shall be of rayon banner, measure 4′4″ on hoist by 5′6″ on the fly, exclusive of heading and hems, and be fringed on three edges with yellow rayon fringe, 21/2″ wide. (2) The outdoor flag shall be...

  7. 10 CFR 1002.21 - Description of distinguishing flag.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... shall be of rayon banner, measure 4′4″ on hoist by 5′6″ on the fly, exclusive of heading and hems, and be fringed on three edges with yellow rayon fringe, 21/2″ wide. (2) The outdoor flag shall be...

  8. 10 CFR 1002.21 - Description of distinguishing flag.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... shall be of rayon banner, measure 4′4″ on hoist by 5′6″ on the fly, exclusive of heading and hems, and be fringed on three edges with yellow rayon fringe, 21/2″ wide. (2) The outdoor flag shall be...

  9. 10 CFR 1002.21 - Description of distinguishing flag.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... shall be of rayon banner, measure 4′4″ on hoist by 5′6″ on the fly, exclusive of heading and hems, and be fringed on three edges with yellow rayon fringe, 21/2″ wide. (2) The outdoor flag shall be...

  10. Red Flags in Prospective Contractor’s Financial Statement

    DTIC Science & Technology

    1989-12-01

    Increase in Intangible Asset Balances ........ ............... .. 26 2. Red Flags in Liability .... ........... .. 26 a. Current Liability...continued, can lead to operating difficulties. f. An Unusual Increase in Intangible Asset Balances An unusual increase in intangible asset balances...maintenance indicates profitability and potential operating difficulties. 15. An unusual increase in intangible asset balances signals that the company may be

  11. 36 CFR 520.10 - Placards, signs, banners, and flags.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 3 2013-07-01 2012-07-01 true Placards, signs, banners, and flags. 520.10 Section 520.10 Parks, Forests, and Public Property SMITHSONIAN INSTITUTION RULES AND REGULATIONS GOVERNING THE BUILDINGS AND GROUNDS OF THE NATIONAL ZOOLOGICAL PARK OF THE SMITHSONIAN...

  12. 36 CFR 504.9 - Placards, signs, banners and flags.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false Placards, signs, banners and flags. 504.9 Section 504.9 Parks, Forests, and Public Property SMITHSONIAN INSTITUTION RULES AND REGULATIONS GOVERNING SMITHSONIAN INSTITUTION BUILDINGS AND GROUNDS § 504.9 Placards, signs, banners and...

  13. 36 CFR 520.10 - Placards, signs, banners, and flags.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Placards, signs, banners, and flags. 520.10 Section 520.10 Parks, Forests, and Public Property SMITHSONIAN INSTITUTION RULES AND REGULATIONS GOVERNING THE BUILDINGS AND GROUNDS OF THE NATIONAL ZOOLOGICAL PARK OF THE SMITHSONIAN...

  14. 36 CFR 520.10 - Placards, signs, banners, and flags.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Placards, signs, banners, and flags. 520.10 Section 520.10 Parks, Forests, and Public Property SMITHSONIAN INSTITUTION RULES AND REGULATIONS GOVERNING THE BUILDINGS AND GROUNDS OF THE NATIONAL ZOOLOGICAL PARK OF THE SMITHSONIAN...

  15. 36 CFR 504.9 - Placards, signs, banners and flags.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 3 2013-07-01 2012-07-01 true Placards, signs, banners and flags. 504.9 Section 504.9 Parks, Forests, and Public Property SMITHSONIAN INSTITUTION RULES AND REGULATIONS GOVERNING SMITHSONIAN INSTITUTION BUILDINGS AND GROUNDS § 504.9 Placards, signs, banners and...

  16. 36 CFR 520.10 - Placards, signs, banners, and flags.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 3 2012-07-01 2012-07-01 false Placards, signs, banners, and flags. 520.10 Section 520.10 Parks, Forests, and Public Property SMITHSONIAN INSTITUTION RULES AND REGULATIONS GOVERNING THE BUILDINGS AND GROUNDS OF THE NATIONAL ZOOLOGICAL PARK OF THE SMITHSONIAN...

  17. 36 CFR 504.9 - Placards, signs, banners and flags.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Placards, signs, banners and flags. 504.9 Section 504.9 Parks, Forests, and Public Property SMITHSONIAN INSTITUTION RULES AND REGULATIONS GOVERNING SMITHSONIAN INSTITUTION BUILDINGS AND GROUNDS § 504.9 Placards, signs, banners and...

  18. 36 CFR 504.9 - Placards, signs, banners and flags.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 3 2012-07-01 2012-07-01 false Placards, signs, banners and flags. 504.9 Section 504.9 Parks, Forests, and Public Property SMITHSONIAN INSTITUTION RULES AND REGULATIONS GOVERNING SMITHSONIAN INSTITUTION BUILDINGS AND GROUNDS § 504.9 Placards, signs, banners and...

  19. 36 CFR 520.10 - Placards, signs, banners, and flags.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false Placards, signs, banners, and flags. 520.10 Section 520.10 Parks, Forests, and Public Property SMITHSONIAN INSTITUTION RULES AND REGULATIONS GOVERNING THE BUILDINGS AND GROUNDS OF THE NATIONAL ZOOLOGICAL PARK OF THE SMITHSONIAN...

  20. 36 CFR 504.9 - Placards, signs, banners and flags.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Placards, signs, banners and flags. 504.9 Section 504.9 Parks, Forests, and Public Property SMITHSONIAN INSTITUTION RULES AND REGULATIONS GOVERNING SMITHSONIAN INSTITUTION BUILDINGS AND GROUNDS § 504.9 Placards, signs, banners and...

  1. Soccer-Speedball-Flag Football Guide. June 1974-June 1976.

    ERIC Educational Resources Information Center

    Faber, Dolores, Ed.; And Others

    This guide, produced by the National Association for Girls and Women in Sport (NAGWS), is a collection of essays by various authors on soccer, speedball, and flag football. There is a separate section for each sport. In the section, the following topics are covered: goalkeeping, the use of tires as a teaching aid, skill testing, problem-solving…

  2. 46 CFR 153.9 - Foreign flag vessel endorsement application.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Certificates issued by the vessel's administration and— (1) An additional classification society statement that... Compliance endorsed with the name of an alkylene oxide; and (2) An additional classification society...) The name of the vessel's flag administration. (6) The name of the society that classes the vessel....

  3. 46 CFR 153.9 - Foreign flag vessel endorsement application.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... endorsement from the cognizant Officer in Charge, Marine Inspection and have aboard the vessel copies of IMO Certificates issued by the vessel's administration and— (1) An additional classification society statement that... 46 Shipping 5 2014-10-01 2014-10-01 false Foreign flag vessel endorsement application....

  4. 46 CFR 153.9 - Foreign flag vessel endorsement application.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... endorsement from the cognizant Officer in Charge, Marine Inspection and have aboard the vessel copies of IMO Certificates issued by the vessel's administration and— (1) An additional classification society statement that... 46 Shipping 5 2012-10-01 2012-10-01 false Foreign flag vessel endorsement application....

  5. 46 CFR 153.9 - Foreign flag vessel endorsement application.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... endorsement from the cognizant Officer in Charge, Marine Inspection and have aboard the vessel copies of IMO Certificates issued by the vessel's administration and— (1) An additional classification society statement that... 46 Shipping 5 2013-10-01 2013-10-01 false Foreign flag vessel endorsement application....

  6. 46 CFR 153.9 - Foreign flag vessel endorsement application.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... endorsement from the cognizant Officer in Charge, Marine Inspection and have aboard the vessel copies of IMO Certificates issued by the vessel's administration and— (1) An additional classification society statement that... 46 Shipping 5 2011-10-01 2011-10-01 false Foreign flag vessel endorsement application....

  7. 14 CFR 1221.106 - Establishment of the NASA Flag.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Establishment of the NASA Flag. 1221.106 Section 1221.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION THE NASA SEAL AND OTHER DEVICES, AND THE CONGRESSIONAL SPACE MEDAL OF HONOR NASA Seal, NASA Insignia, NASA Logotype,...

  8. 14 CFR 1221.113 - Use of the NASA Flags.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Use of the NASA Flags. 1221.113 Section 1221.113 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION THE NASA SEAL AND OTHER DEVICES, AND THE CONGRESSIONAL SPACE MEDAL OF HONOR NASA Seal, NASA Insignia, NASA Logotype, NASA...

  9. 14 CFR 1221.106 - Establishment of the NASA Flag.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Establishment of the NASA Flag. 1221.106 Section 1221.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION THE NASA SEAL AND OTHER DEVICES, AND THE CONGRESSIONAL SPACE MEDAL OF HONOR NASA Seal, NASA Insignia, NASA Logotype,...

  10. 14 CFR 1221.106 - Establishment of the NASA Flag.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Establishment of the NASA Flag. 1221.106 Section 1221.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION THE NASA SEAL AND OTHER DEVICES, AND THE CONGRESSIONAL SPACE MEDAL OF HONOR NASA Seal, NASA Insignia, NASA Logotype,...

  11. 14 CFR 1221.113 - Use of the NASA Flags.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Use of the NASA Flags. 1221.113 Section 1221.113 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION THE NASA SEAL AND OTHER DEVICES, AND THE CONGRESSIONAL SPACE MEDAL OF HONOR NASA Seal, NASA Insignia, NASA Logotype, NASA...

  12. 14 CFR 1221.113 - Use of the NASA Flags.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Use of the NASA Flags. 1221.113 Section 1221.113 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION THE NASA SEAL AND OTHER DEVICES, AND THE CONGRESSIONAL SPACE MEDAL OF HONOR NASA Seal, NASA Insignia, NASA Logotype, NASA...

  13. 14 CFR 1221.106 - Establishment of the NASA Flag.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Establishment of the NASA Flag. 1221.106 Section 1221.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION THE NASA SEAL AND OTHER DEVICES, AND THE CONGRESSIONAL SPACE MEDAL OF HONOR NASA Seal, NASA Insignia, NASA Logotype,...

  14. 14 CFR 1221.113 - Use of the NASA Flags.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Use of the NASA Flags. 1221.113 Section 1221.113 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION THE NASA SEAL AND OTHER DEVICES, AND THE CONGRESSIONAL SPACE MEDAL OF HONOR NASA Seal, NASA Insignia, NASA Logotype, NASA...

  15. 77 FR 13449 - Identity Theft Red Flags Rules

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-06

    ... Commission 17 CFR Part 248 Identity Theft Red Flags Rules; Proposed Rule #0;#0;Federal Register / Vol. 77... Part 162 RIN 3038-AD14 SECURITIES AND EXCHANGE COMMISSION 17 CFR Part 248 RIN 3235-AL26 Identity Theft... that are subject to the Commissions' jurisdiction to address identity theft in two ways. First,...

  16. Modifying Flag Football for Gender Equitable Engagement in Secondary Schools

    ERIC Educational Resources Information Center

    Kahan, David

    2008-01-01

    Flag or touch football is a popular activity unit in American secondary physical education curricula. However, unlike other sports its stigmatization as a masculine-typed activity and frequent inequitable distribution of game play opportunities at the skill positions (e.g., receiver, quarterback) results in the marginalization of female…

  17. 46 CFR 252.22 - Substantiality and extent of foreign-flag competition.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Substantiality and extent of foreign-flag competition... WORLDWIDE SERVICES Operation § 252.22 Substantiality and extent of foreign-flag competition. (a) Type and tonnage groupings. Foreign-flag competition shall be determined, as of January 1 of the year...

  18. 46 CFR 252.22 - Substantiality and extent of foreign-flag competition.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Substantiality and extent of foreign-flag competition... WORLDWIDE SERVICES Operation § 252.22 Substantiality and extent of foreign-flag competition. (a) Type and tonnage groupings. Foreign-flag competition shall be determined, as of January 1 of the year...

  19. 10 CFR 1002.3 - Custody of official seal and distinguishing flags.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Custody of official seal and distinguishing flags. 1002.3 Section 1002.3 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICIAL SEAL AND DISTINGUISHING FLAG General § 1002.3 Custody of official seal and distinguishing flags. The Secretary or his designee...

  20. 10 CFR 1002.3 - Custody of official seal and distinguishing flags.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Custody of official seal and distinguishing flags. 1002.3 Section 1002.3 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICIAL SEAL AND DISTINGUISHING FLAG General § 1002.3 Custody of official seal and distinguishing flags. The Secretary or his designee...

  1. 10 CFR 1002.31 - Unauthorized uses of the seal and flag.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Unauthorized uses of the seal and flag. 1002.31 Section 1002.31 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICIAL SEAL AND DISTINGUISHING FLAG Unauthorized Uses § 1002.31 Unauthorized uses of the seal and flag. The official seal and distinguishing...

  2. 10 CFR 1002.31 - Unauthorized uses of the seal and flag.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Unauthorized uses of the seal and flag. 1002.31 Section 1002.31 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICIAL SEAL AND DISTINGUISHING FLAG Unauthorized Uses § 1002.31 Unauthorized uses of the seal and flag. The official seal and distinguishing...

  3. 10 CFR 1002.31 - Unauthorized uses of the seal and flag.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Unauthorized uses of the seal and flag. 1002.31 Section 1002.31 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICIAL SEAL AND DISTINGUISHING FLAG Unauthorized Uses § 1002.31 Unauthorized uses of the seal and flag. The official seal and distinguishing...

  4. 10 CFR 1002.3 - Custody of official seal and distinguishing flags.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Custody of official seal and distinguishing flags. 1002.3 Section 1002.3 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICIAL SEAL AND DISTINGUISHING FLAG General § 1002.3 Custody of official seal and distinguishing flags. The Secretary or his designee...

  5. 10 CFR 1002.31 - Unauthorized uses of the seal and flag.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Unauthorized uses of the seal and flag. 1002.31 Section 1002.31 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICIAL SEAL AND DISTINGUISHING FLAG Unauthorized Uses § 1002.31 Unauthorized uses of the seal and flag. The official seal and distinguishing...

  6. 10 CFR 1002.31 - Unauthorized uses of the seal and flag.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Unauthorized uses of the seal and flag. 1002.31 Section 1002.31 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICIAL SEAL AND DISTINGUISHING FLAG Unauthorized Uses § 1002.31 Unauthorized uses of the seal and flag. The official seal and distinguishing...

  7. 10 CFR 1002.3 - Custody of official seal and distinguishing flags.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Custody of official seal and distinguishing flags. 1002.3 Section 1002.3 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICIAL SEAL AND DISTINGUISHING FLAG General § 1002.3 Custody of official seal and distinguishing flags. The Secretary or his designee...

  8. 10 CFR 1002.3 - Custody of official seal and distinguishing flags.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Custody of official seal and distinguishing flags. 1002.3 Section 1002.3 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICIAL SEAL AND DISTINGUISHING FLAG General § 1002.3 Custody of official seal and distinguishing flags. The Secretary or his designee...

  9. 38 CFR 1.9 - Description, use, and display of VA seal and flag.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... in its talons. The cord binds a 13-star U.S. flag and a 50-star U.S. flag. In the field over the eagle is a pentagon formation of stars, with one point down. The words Department of Veterans Affairs and United States of America surround the eagle, stars, and flags. A rope motif makes up the...

  10. 38 CFR 1.9 - Description, use, and display of VA seal and flag.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... in its talons. The cord binds a 13-star U.S. flag and a 50-star U.S. flag. In the field over the eagle is a pentagon formation of stars, with one point down. The words Department of Veterans Affairs and United States of America surround the eagle, stars, and flags. A rope motif makes up the...

  11. 38 CFR 1.9 - Description, use, and display of VA seal and flag.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... in its talons. The cord binds a 13-star U.S. flag and a 50-star U.S. flag. In the field over the eagle is a pentagon formation of stars, with one point down. The words Department of Veterans Affairs and United States of America surround the eagle, stars, and flags. A rope motif makes up the...

  12. 38 CFR 1.9 - Description, use, and display of VA seal and flag.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... in its talons. The cord binds a 13-star U.S. flag and a 50-star U.S. flag. In the field over the eagle is a pentagon formation of stars, with one point down. The words Department of Veterans Affairs and United States of America surround the eagle, stars, and flags. A rope motif makes up the...

  13. 38 CFR 1.9 - Description, use, and display of VA seal and flag.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... in its talons. The cord binds a 13-star U.S. flag and a 50-star U.S. flag. In the field over the eagle is a pentagon formation of stars, with one point down. The words Department of Veterans Affairs and United States of America surround the eagle, stars, and flags. A rope motif makes up the...

  14. 46 CFR 381.9 - Available U.S.-flag service.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Available U.S.-flag service. 381.9 Section 381.9 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION MISCELLANEOUS CARGO PREFERENCE-U.S.-FLAG VESSELS § 381.9 Available U.S.-flag service. For purposes of shipping bulk agricultural commodities...

  15. 14 CFR 121.687 - Dispatch release: Flag and domestic operations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Dispatch release: Flag and domestic... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Records and Reports § 121.687 Dispatch release: Flag and domestic operations. (a) The dispatch release may be in any form but must contain...

  16. 14 CFR 121.687 - Dispatch release: Flag and domestic operations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Dispatch release: Flag and domestic... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Records and Reports § 121.687 Dispatch release: Flag and domestic operations. (a) The dispatch release may be in any form but must contain...

  17. 14 CFR 121.687 - Dispatch release: Flag and domestic operations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Dispatch release: Flag and domestic... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Records and Reports § 121.687 Dispatch release: Flag and domestic operations. (a) The dispatch release may be in any form but must contain...

  18. 14 CFR 121.615 - Dispatch or flight release over water: Flag and supplemental operations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Dispatch or flight release over water: Flag...: CERTIFICATION AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.615 Dispatch or flight release over water: Flag and supplemental...

  19. 14 CFR 121.615 - Dispatch or flight release over water: Flag and supplemental operations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Dispatch or flight release over water: Flag...: CERTIFICATION AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.615 Dispatch or flight release over water: Flag and supplemental...

  20. 14 CFR 121.615 - Dispatch or flight release over water: Flag and supplemental operations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Dispatch or flight release over water: Flag...: CERTIFICATION AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.615 Dispatch or flight release over water: Flag and supplemental...

  1. 14 CFR 121.615 - Dispatch or flight release over water: Flag and supplemental operations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Dispatch or flight release over water: Flag...: CERTIFICATION AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.615 Dispatch or flight release over water: Flag and supplemental...

  2. 14 CFR 121.687 - Dispatch release: Flag and domestic operations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Dispatch release: Flag and domestic... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Records and Reports § 121.687 Dispatch release: Flag and domestic operations. (a) The dispatch release may be in any form but must contain...

  3. 14 CFR 121.615 - Dispatch or flight release over water: Flag and supplemental operations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Dispatch or flight release over water: Flag...: CERTIFICATION AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.615 Dispatch or flight release over water: Flag and supplemental...

  4. 76 FR 20080 - Inventory of U.S.-Flag Launch Barges

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-11

    ... Maritime Administration Inventory of U.S.-Flag Launch Barges AGENCY: Maritime Administration, Department of Transportation. ACTION: Inventory of U.S.-Flag Launch Barges. SUMMARY: The Maritime Administration is updating its inventory of U.S.- flag launch barges. Additions, changes and comments to the list are...

  5. 77 FR 20098 - Inventory of U.S.-Flag Launch Barges

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-03

    ... Maritime Administration Inventory of U.S.-Flag Launch Barges AGENCY: Maritime Administration, Department of Transportation. ACTION: Inventory of U.S.-Flag Launch Barges. SUMMARY: The Maritime Administration is updating its inventory of U.S.- flag launch barges. Additions, changes and comments to the list are...

  6. 75 FR 13645 - Inventory of U.S.-Flag Launch Barges

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-22

    ... Maritime Administration Inventory of U.S.-Flag Launch Barges AGENCY: Maritime Administration, Department of Transportation. ACTION: Inventory of U.S.-Flag Launch Barges. SUMMARY: The Maritime Administration is updating its inventory of U.S.- flag launch barges. Additions, changes and comments to the list are...

  7. Reference genes for gene expression studies in wheat flag leaves grown under different farming conditions

    PubMed Central

    2011-01-01

    Background Internal control genes with highly uniform expression throughout the experimental conditions are required for accurate gene expression analysis as no universal reference genes exists. In this study, the expression stability of 24 candidate genes from Triticum aestivum cv. Cubus flag leaves grown under organic and conventional farming systems was evaluated in two locations in order to select suitable genes that can be used for normalization of real-time quantitative reverse-transcription PCR (RT-qPCR) reactions. The genes were selected among the most common used reference genes as well as genes encoding proteins involved in several metabolic pathways. Findings Individual genes displayed different expression rates across all samples assayed. Applying geNorm, a set of three potential reference genes were suitable for normalization of RT-qPCR reactions in winter wheat flag leaves cv. Cubus: TaFNRII (ferredoxin-NADP(H) oxidoreductase; AJ457980.1), ACT2 (actin 2; TC234027), and rrn26 (a putative homologue to RNA 26S gene; AL827977.1). In addition of these three genes that were also top-ranked by NormFinder, two extra genes: CYP18-2 (Cyclophilin A, AY456122.1) and TaWIN1 (14-3-3 like protein, AB042193) were most consistently stably expressed. Furthermore, we showed that TaFNRII, ACT2, and CYP18-2 are suitable for gene expression normalization in other two winter wheat varieties (Tommi and Centenaire) grown under three treatments (organic, conventional and no nitrogen) and a different environment than the one tested with cv. Cubus. Conclusions This study provides a new set of reference genes which should improve the accuracy of gene expression analyses when using wheat flag leaves as those related to the improvement of nitrogen use efficiency for cereal production. PMID:21951810

  8. Department of Defense, General/Flag Officer, Worldwide Roster

    DTIC Science & Technology

    1998-06-01

    USN 9707 970627 3 GENERAL/FLAG OFFICER WORLDWIDE ROSTER DATE DATE OF DUTY TITLE NAME RANK SERVICE ASSIGNED RANK DEP DIR J-8 CARTWRIGHT JAMES E BG* USMC...SIGNAL BRIGADE - SPARTANBURG,SC COMMANDER (RC) SIMPSON DARWIN H BG ARNG 9603 970303 263RD AIR DEFENSE ARTILLERY BRIGADE - ANDERSON,SC COMMANDER (RC...N ................. 27 CARSKADON BRUCE M ................. 28 CARTWRIGHT JAMES E ................ 04 CASCIANO JOHN P ................... 27 CASE

  9. Feline reference intervals for the Sysmex XT-2000iV and the ProCyte DX haematology analysers in EDTA and CTAD blood specimens.

    PubMed

    Granat, Fanny; Geffré, Anne; Bourgès-Abella, Nathalie; Mortier, Jeremy; Théron, Marie-Laure; Fauchon, Emilie; Braun, Jean-Pierre; Trumel, Catherine

    2014-06-01

    Laser-based haematology analysers are routinely used in veterinary clinical pathology laboratories, and are available to practitioners. However, feline haematological reference intervals (RIs) determined according to international recommendations are, to our knowledge, not available. Furthermore, platelet count RI is difficult to establish in cats because of the frequent occurrence of platelet aggregation in blood specimens. The purpose of this study was to establish feline haematological RIs with the Sysmex XT-2000iV and ProCyte DX analysers, in ethylenediamine tetra-acetic acid (EDTA) and in citrate, theophylline, adenosine and dipyridamole (CTAD), which is a combination of anticoagulants limiting platelet aggregation. Blood specimens from 120 healthy cats were analysed in duplicate, and the degree of platelet aggregation was assessed on blood smears. After exclusion of inadequate specimens, 81 sets of results (from 44 males and 37 females, aged from 6 to 116 months) were available for the determination of RIs by the non-parametric method. The effects of the anticoagulant, analyser and aggregation score were assessed. When the aggregation effect was significant, the RIs were determined using the subgroup of blood specimens with no or little aggregation. The effects of sex, age and weight were also investigated, but were moderate. The different RIs obtained with the Sysmex XT-2000iV and ProCyte DX analysers, and the two anticoagulants, were very similar to previous RIs established in EDTA with the ADVIA 120, another laser-based analyser, except for the platelet count in CTAD specimens. Its lower reference limit was higher in CTAD vs EDTA specimens, which confirms the interest in this anticoagulant in cats.

  10. Vortex dynamics and flapping patterns of the inverted flag with a bluff body

    NASA Astrophysics Data System (ADS)

    Kim, Hyeonseong; Kim, Junyoung; Kim, Daegyoum

    2015-11-01

    Flow-induced vibration of flexible structures for energy harvesting has drawn attention recently. The inverted flag whose trailing edge is clamped and leading edge is free to move was known to self-excite in a uniform flow of both water and air. In this study, we investigated the effect of an upstream bluff body, a flat plate, on the dynamics of the downstream inverted flag. Periodic vortical structures created by an upstream bluff body make the dynamics of the inverted flag quite different from those of the inverted flag without the bluff body. We examined the motion of the inverted flag by varying the relative displacement of the inverted flag from the bluff body and their relative size. Our results show that the inverted flag can flap with higher frequency and larger amplitude with the upstream bluff body. We also compared the dynamics of the inverted flag with those of the general flag with the upstream bluff body. In order to better understand the dynamics of the flag, the analysis of the flow patterns using particle image velocimetry was also conducted.

  11. THE FLAG: A Web Resource of Innovative Assessment Tools for Faculty in College Science, Mathematics, Engineering, and Technology

    NASA Astrophysics Data System (ADS)

    Zeilik, M.; Mathieu, R. D.; National InstituteScience Education; College Level-One Team

    2000-12-01

    Even the most dedicated college faculty often discover that their students fail to learn what was taught in their courses and that much of what students do learn is quickly forgotten after the final exam. To help college faculty improve student learning in college Science, Mathematics, Engineering and Technology (SMET), the College Level - One Team of the National Institute for Science Education has created the "FLAG" a Field-tested Learning Assessment Guide for SMET faculty. Developed with funding from the National Science Foundation, the FLAG presents in guidebook format a diverse and robust collection of field-tested classroom assessment techniques (CATs), with supporting information on how to apply them in the classroom. Faculty can download the tools and techniques from the website, which also provides a goals clarifier, an assessment primer, a searchable database, and links to additional resources. The CATs and tools have been reviewed by an expert editorial board and the NISE team. These assessment strategies can help faculty improve the learning environments in their SMET courses especially the crucial introductory courses that most strongly shape students' college learning experiences. In addition, the FLAG includes the web-based Student Assessment of Learning Gains. The SALG offers a convenient way to evaluate the impact of your courses on students. It is based on findings that students' estimates of what they gained are more reliable and informative than their observations of what they liked about the course or teacher. It offers accurate feedback on how well the different aspects of teaching helped the students to learn. Students complete the SALG online after a generic template has been modified to fit the learning objectives and activities of your course. The results are presented to the teacher as summary statistics automatically. The FLAG can be found at the NISE "Innovations in SMET Education" website at www.wcer.wisc.edu/nise/cl1

  12. Astronaut Returns Space-Flown Flag to NRAO

    NASA Astrophysics Data System (ADS)

    2002-04-01

    A NASA Astronaut who carried a flag bearing the logo of the National Radio Astronomy Observatory (NRAO) on last month's Shuttle flight returned that flag to the observatory on Friday, April 12, at a ceremony in Socorro. Dr. John M. Grunsfeld, payload commander of the STS-109 flight, also addressed students at the New Mexico State Science Fair on Saturday, April 13, on the campus of New Mexico Tech in Socorro. Dr. John M. Grunsfeld: Click on image for larger view Dr. John M. Grunsfeld Grunsfeld, an astronomer who observed with NRAO's Very Large Array (VLA) radio telescope in 1991, carried the 3-by-5-foot NRAO flag aboard Columbia during the March 1-12 mission to service the Hubble Space Telescope. The NRAO flag, made by Socorro resident Dora Spargo, had been sent to the observatory's facilities in Socorro; Tucson, AZ; Green Bank, WV; and Charlottesville, VA, where NRAO employees signed it prior to the flight. "With our signatures on that flag, we all felt like we were riding along with John aboard the Shuttle," said NRAO Director Paul Vanden Bout. "We are proud that NRAO was represented on a mission that was so important to astronomy," Vanden Bout added. During the flight, Grunsfeld performed three of the five spacewalks in which crew members successfully upgraded the Hubble Space Telescope. The astronauts left the space observatory with a new power unit, a new camera and new solar arrays. The upgrades, said Grunsfeld, leave the orbiting telescope with "its discovery potential significantly increased." STS-109 was Grunsfeld's fourth space flight and his second visit to Hubble. A research astronomer who received his bachelor's degree in physics from MIT and a Ph.D from the University of Chicago in 1988, Grunsfeld was selected to the astronaut corps in 1992. His first space flight, in 1995, featured astronomical observations using the Astro observatory, a three-telescope facility aboard the Shuttle Endeavour. In 1997, Grunsfeld rode Atlantis on a 10-day mission to the

  13. Astronaut John Young leaps from lunar surface to salute flag

    NASA Technical Reports Server (NTRS)

    1972-01-01

    Astronaut John W. Young, commander of the Apollo 16 lunar landing mission, leaps from the lunar surface as he salutes the U.S. Flag at the Descartes landing site during the first Apollo 16 extravehicular activity (EVA-1). Astronaut Charles M. Duke Jr., lunar module pilot, took this picture. The Lunar Module (LM) 'Orion' is on the left. The Lunar Roving Vehicle is parked beside the LM. The object behind Young in the shade of the LM is the Far Ultraviolet Camera/Spectrograph. Stone Mountain dominates the background in this lunar scene.

  14. Swimming between the flags: a preliminary exploration of the influences on Australians' intentions to swim between the flags at patrolled beaches.

    PubMed

    White, Katherine M; Hyde, Melissa K

    2010-11-01

    Swimming at patrolled beaches reduces the likelihood of drownings and near-drownings. The present study tested the Theory of Planned Behaviour (TPB), with the addition of risk perceptions, in predicting people's intentions to swim between the flags at patrolled beaches. We examined also the predictors of people's willingness to swim [1] up to 10 m and [2] more than 10 m outside of the patrol flags. Participants (N=526) completed measures of attitudes, subjective norm, perceived behavioural control (PBC), intentions/willingness, and both objective and subjective risk perceptions. Two weeks later, a sub-sample of participants reported on their beach swimming behaviour for the previous fortnight. Attitude and subjective norm predicted intentions to swim between and willingness to swim outside of the flags. Age and PBC influenced willingness to swim beyond the flags. Objective risk predicted willingness to swim beyond the flags (both distances) while subjective risk predicted willingness to swim up to 10 m outside the flags. People's intentions to swim between the flags were correlated with their behaviour at follow-up. This study provides a preliminary investigation into an important safety behaviour and identifies factors to target when promoting safe swimming behaviours to prevent drowning deaths on Australian beaches.

  15. Dynamic Black-Level Correction and Artifact Flagging for Kepler Pixel Time Series

    NASA Technical Reports Server (NTRS)

    Kolodziejczak, J. J.; Clarke, B. D.; Caldwell, D. A.

    2011-01-01

    Methods applied to the calibration stage of Kepler pipeline data processing [1] (CAL) do not currently use all of the information available to identify and correct several instrument-induced artifacts. These include time-varying crosstalk from the fine guidance sensor (FGS) clock signals, and manifestations of drifting moire pattern as locally correlated nonstationary noise, and rolling bands in the images which find their way into the time series [2], [3]. As the Kepler Mission continues to improve the fidelity of its science data products, we are evaluating the benefits of adding pipeline steps to more completely model and dynamically correct the FGS crosstalk, then use the residuals from these model fits to detect and flag spatial regions and time intervals of strong time-varying black-level which may complicate later processing or lead to misinterpretation of instrument behavior as stellar activity.

  16. Riemannian Optimization Method on Generalized Flag Manifolds for Complex and Subspace ICA

    NASA Astrophysics Data System (ADS)

    Nishimori, Yasunori; Akaho, Shotaro; Plumbley, Mark D.

    2006-11-01

    In this paper we introduce a new class of manifolds, generalized flag manifolds, for the complex and subspace ICA problems. A generalized flag manifold is a manifold consisting of subspaces which are orthogonal to each other. The class of generalized flag manifolds include the class of Grassmann manifolds. We extend the Riemannian optimization method to include this new class of manifolds by deriving the formulas for the natural gradient and geodesics on these manifolds. We show how the complex and subspace ICA problems can be solved by optimization of cost functions on a generalized flag manifold. Computer simulations demonstrate our algorithm gives good performance compared with the ordinary gradient descent method.

  17. 14 CFR 121.637 - Takeoffs from unlisted and alternate airports: Domestic and flag operations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...: CERTIFICATION AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and... dispatched according to dispatching rules applicable to operation from an approved airport; and (4)...

  18. 14 CFR 121.637 - Takeoffs from unlisted and alternate airports: Domestic and flag operations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...: CERTIFICATION AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and... dispatched according to dispatching rules applicable to operation from an approved airport; and (4)...

  19. 14 CFR 121.637 - Takeoffs from unlisted and alternate airports: Domestic and flag operations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...: CERTIFICATION AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and... dispatched according to dispatching rules applicable to operation from an approved airport; and (4)...

  20. 75 FR 66125 - Federal Land Managers' Air Quality Related Values Work Group (FLAG)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-27

    ... National Park Service Federal Land Managers' Air Quality Related Values Work Group (FLAG) AGENCY: National...' Air Quality Related Values Work Group (FLAG) was formed (1) to develop a more consistent and objective... their air quality related values (AQRVs); and (2) to provide State permitting authorities and...

  1. Flag Protection: A Brief History and Summary of Recent Supreme Court Decisions and Proposed Constitutional Amendment

    DTIC Science & Technology

    2005-05-19

    conduct under the First Amendment , and the symbolic importance of the United States flag. Consequently, every Congress that has convened since those...desecration under a Texas statute was inconsistent with the First Amendment and affirmed a decision of the Texas Court of Criminal Appeals that barred punishment for burning the flag as part of a public demonstration.

  2. 77 FR 326 - Agency Information Collection (Application for United States Flag for Burial Purposes): Activity...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-04

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF VETERANS AFFAIRS Agency Information Collection (Application for United States Flag for Burial Purposes): Activity....'' SUPPLEMENTARY INFORMATION: Title: Application for United States Flag for Burial Purposes, VA Form 21-2008....

  3. 76 FR 61148 - Proposed Information Collection (Application for United States Flag for Burial Purposes) Activity...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-03

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF VETERANS AFFAIRS Proposed Information Collection (Application for United States Flag for Burial Purposes) Activity... information technology. Title: Application for United States Flag for Burial Purposes, VA Form 21-2008....

  4. Astronaut Harrison Schmitt next to deployed U.S. flag on lunar surface

    NASA Technical Reports Server (NTRS)

    1972-01-01

    Scientist-Astronaut Harrison Schmitt, Apollo 17 lunar module pilot, is photographed next to the U.S. flag during extravehicular activity (EVA) of NASA's final lunar landing mission in the Apollo series. The photo was taken at the Taurus-Littrow landing site. The highest part of the flag appears to point toward our planet earth in the distant background.

  5. For Which It Stands: Flag Burning and the First Amendment. Teacher's Guide.

    ERIC Educational Resources Information Center

    Thompson, Marcia A.; Sass, Charles R.

    This teacher's guide is designed to accompany the two-part videotape "For Which It Stands: Flag Burning and the First Amendment." The videotape and teacher's guide should help students to: (1) understand the emotion and significance of the flag-burning issue; (2) examine the free speech aspect of the First Amendment of the Bill of…

  6. 14 CFR 121.621 - Alternate airport for destination: Flag operations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Alternate airport for destination: Flag... § 121.621 Alternate airport for destination: Flag operations. (a) No person may dispatch an airplane under IFR or over-the-top unless he lists at least one alternate airport for each destination airport...

  7. 14 CFR 121.621 - Alternate airport for destination: Flag operations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Alternate airport for destination: Flag... § 121.621 Alternate airport for destination: Flag operations. (a) No person may dispatch an airplane under IFR or over-the-top unless he lists at least one alternate airport for each destination airport...

  8. 14 CFR 121.637 - Takeoffs from unlisted and alternate airports: Domestic and flag operations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... airports: Domestic and flag operations. 121.637 Section 121.637 Aeronautics and Space FEDERAL AVIATION... Flight Release Rules § 121.637 Takeoffs from unlisted and alternate airports: Domestic and flag operations. (a) No pilot may takeoff an airplane from an airport that is not listed in the...

  9. 14 CFR 121.637 - Takeoffs from unlisted and alternate airports: Domestic and flag operations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... airports: Domestic and flag operations. 121.637 Section 121.637 Aeronautics and Space FEDERAL AVIATION... Flight Release Rules § 121.637 Takeoffs from unlisted and alternate airports: Domestic and flag operations. (a) No pilot may takeoff an airplane from an airport that is not listed in the...

  10. 14 CFR 121.99 - Communications facilities-domestic and flag operations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... operations. 121.99 Section 121.99 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Approval of Routes: Domestic and Flag... communication approved by the FAA certificate holding district office, is available over the entire route....

  11. FlagHouse Forum: You Say "Tomato"... and I Use a Communicator

    ERIC Educational Resources Information Center

    Exceptional Parent, 2011

    2011-01-01

    This month's "FlagHouse Forum" focuses on how to choose the communicator best-suited to a child's special need. FlagHouse--a premier global supplier of resources for special needs, education, physical activity and recreation--is pleased to partner with "Exceptional Parent" to bring its readers this informational forum. Humans communicate with each…

  12. Enhancement of heat transfer by clamped flags in a Poiseuille channel flow

    NASA Astrophysics Data System (ADS)

    Lee, Jae Bok; Park, Sung Goon; Kim, Boyoung; Sung, Hyung Jin

    2016-11-01

    A pair of flexible flags clamped vertically in a heated channel was numerically modeled to study an enhancement of heat transfer by the clamped flags in a Poiseuille channel flow. The penalty immersed boundary method was adopted to analyze the fluid-structure-thermal interaction between the surrounding fluid and the clamped flags. The dynamics of the clamped flags was categorized into three distinctive modes: a flapping mode, a fully deflected mode, and an irregular mode. The distinctive modes that depended on the relationship between the hydrodynamic force and the restoring force displayed different movement patterns. The flapping mode provided superior thermal performance to the other modes. Vortices generated from the flapping flags swept out the thermal boundary layer and entrained the fluid near channel walls into the channel core flow while passing through the wake periodically. Compared to rigid flags, the flapping flags significantly improved the thermal efficiency. In addition, the effects of channel height and Reynolds number on the thermal efficiency were explored to obtain an optimal parameter set, which presented the highest thermal performance in present study. The flexible flags regarding the optimal parameter set showed an increase of up to 230% in net heat flux, compared to the baseline flow. Dynamic modes decomposition (DMD) method was adopted to examine the correlation between the vorticity and temperature fields.

  13. 40 CFR 161.34 - Flagging of studies for potential adverse effects.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 25 2013-07-01 2013-07-01 false Flagging of studies for potential... Provisions § 161.34 Flagging of studies for potential adverse effects. (a) Any person who submits a study of... registration, or to satisfy a requirement imposed under FIFRA sec. 3(c)(2)(B), must submit with the study...

  14. 40 CFR 161.34 - Flagging of studies for potential adverse effects.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 25 2012-07-01 2012-07-01 false Flagging of studies for potential... Provisions § 161.34 Flagging of studies for potential adverse effects. (a) Any person who submits a study of... registration, or to satisfy a requirement imposed under FIFRA sec. 3(c)(2)(B), must submit with the study...

  15. 40 CFR 161.34 - Flagging of studies for potential adverse effects.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Flagging of studies for potential... Provisions § 161.34 Flagging of studies for potential adverse effects. (a) Any person who submits a study of... registration, or to satisfy a requirement imposed under FIFRA sec. 3(c)(2)(B), must submit with the study...

  16. 46 CFR 154.19 - U.S. flag vessel: IMO certificate issuance.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.19 U.S. flag vessel: IMO certificate issuance. (a) Either a classification society authorized under 46 CFR part... 46 Shipping 5 2012-10-01 2012-10-01 false U.S. flag vessel: IMO certificate issuance....

  17. 46 CFR 154.19 - U.S. flag vessel: IMO certificate issuance.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.19 U.S. flag vessel: IMO certificate issuance. (a) Either a classification society authorized under 46 CFR part... 46 Shipping 5 2014-10-01 2014-10-01 false U.S. flag vessel: IMO certificate issuance....

  18. 46 CFR 154.19 - U.S. flag vessel: IMO certificate issuance.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.19 U.S. flag vessel: IMO certificate issuance. (a) Either a classification society authorized under 46 CFR part... 46 Shipping 5 2011-10-01 2011-10-01 false U.S. flag vessel: IMO certificate issuance....

  19. 46 CFR 154.19 - U.S. flag vessel: IMO certificate issuance.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.19 U.S. flag vessel: IMO certificate issuance. (a) Either a classification society authorized under 46 CFR part... 46 Shipping 5 2013-10-01 2013-10-01 false U.S. flag vessel: IMO certificate issuance....

  20. 46 CFR 154.19 - U.S. flag vessel: IMO certificate issuance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.19 U.S. flag vessel: IMO certificate issuance. (a) Either a classification society authorized under 46 CFR part... 46 Shipping 5 2010-10-01 2010-10-01 false U.S. flag vessel: IMO certificate issuance....

  1. 75 FR 67453 - Identity Theft Red Flags and Address Discrepancies Under the Fair and Accurate Credit...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-02

    ... Office of Thrift Supervision Identity Theft Red Flags and Address Discrepancies Under the Fair and...: Identity Theft Red Flags and Address Discrepancies under the Fair and Accurate Credit Transactions Act of... issue jointly guidelines for financial institutions and creditors regarding identity theft with...

  2. 14 CFR 121.663 - Responsibility for dispatch release: Domestic and flag operations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Responsibility for dispatch release... AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.663 Responsibility for dispatch release: Domestic and flag operations....

  3. 14 CFR 121.621 - Alternate airport for destination: Flag operations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.621 Alternate airport for destination: Flag operations. (a) No person may dispatch an airplane... the dispatch release, unless— (1) The flight is scheduled for not more than 6 hours and, for at...

  4. 14 CFR 121.663 - Responsibility for dispatch release: Domestic and flag operations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Responsibility for dispatch release... AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.663 Responsibility for dispatch release: Domestic and flag operations....

  5. 14 CFR 121.621 - Alternate airport for destination: Flag operations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.621 Alternate airport for destination: Flag operations. (a) No person may dispatch an airplane... the dispatch release, unless— (1) The flight is scheduled for not more than 6 hours and, for at...

  6. 14 CFR 121.663 - Responsibility for dispatch release: Domestic and flag operations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Responsibility for dispatch release... AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.663 Responsibility for dispatch release: Domestic and flag operations....

  7. 14 CFR 121.663 - Responsibility for dispatch release: Domestic and flag operations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Responsibility for dispatch release... AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.663 Responsibility for dispatch release: Domestic and flag operations....

  8. 14 CFR 121.621 - Alternate airport for destination: Flag operations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.621 Alternate airport for destination: Flag operations. (a) No person may dispatch an airplane... the dispatch release, unless— (1) The flight is scheduled for not more than 6 hours and, for at...

  9. 14 CFR 121.663 - Responsibility for dispatch release: Domestic and flag operations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Responsibility for dispatch release... AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.663 Responsibility for dispatch release: Domestic and flag operations....

  10. Affinity Pull-Down of Proteins Using Anti-FLAG M2 Agarose Beads.

    PubMed

    Gerace, Erica; Moazed, Danesh

    2015-01-01

    FLAG is an affinity tag widely used for rapid and highly specific one-step protein purification. Native elution of protein from anti-FLAG antibody resins allows the identification of protein and nucleic acid binding partners and functional analysis using biochemical activity assays.

  11. Flagging Drugs That Inhibit the Bile Salt Export Pump.

    PubMed

    Montanari, Floriane; Pinto, Marta; Khunweeraphong, Narakorn; Wlcek, Katrin; Sohail, M Imran; Noeske, Tobias; Boyer, Scott; Chiba, Peter; Stieger, Bruno; Kuchler, Karl; Ecker, Gerhard F

    2016-01-04

    The bile salt export pump (BSEP) is an ABC-transporter expressed at the canalicular membrane of hepatocytes. Its physiological role is to expel bile salts into the canaliculi from where they drain into the bile duct. Inhibition of this transporter may lead to intrahepatic cholestasis. Predictive computational models of BSEP inhibition may allow for fast identification of potentially harmful compounds in large databases. This article presents a predictive in silico model based on physicochemical descriptors that is able to flag compounds as potential BSEP inhibitors. This model was built using a training set of 670 compounds with available BSEP inhibition potencies. It successfully predicted BSEP inhibition for two independent test sets and was in a further step used for a virtual screening experiment. After in vitro testing of selected candidates, a marketed drug, bromocriptin, was identified for the first time as BSEP inhibitor. This demonstrates the usefulness of the model to identify new BSEP inhibitors and therefore potential cholestasis perpetrators.

  12. CO2 flagging - an improved method for the collection of questing ticks

    PubMed Central

    2012-01-01

    Background Most epidemiological studies on tick-borne pathogens involve collection of ticks from the environment. An efficient collection method is essential for large sample pools. Our main aim was to evaluate the efficacy of a new method, where traditional flagging was enhanced by the use of CO2 dispersed into the white flannel. The CO2 was spread through a rubber hose network inserted into the flag blanket. The research was conducted in spring, in March-April 2011 in two locations from Cluj County, Romania. Methods The research was conducted in March-April 2011 in two locations from Cluj County, Romania. The flag to be tested contained a fine silicone rubber hose network which dispersed the CO2 in the shaft. On each collection site n=30 samplings were performed. Each sampling consisted in the simultaneous use of both flags (with and without CO2) by two persons. The CO2 concentration level on the flag canvas surface was measured. The efficacy of the method was determined by counting comparatively the total number of ticks and separate developmental stage count. Results Using the CO2 improved flag, 2411 (59%) Ixodes ricinus and 100 (53.8%) Dermacentor marginatus ticks were captured, while the CO2-free flag accounted for the collection of 1670 I. ricinus (41%) and 86 (46.2%) D. marginatus ticks. The addition of CO2 prompted a concentration difference on the surface of the flag ranging between 756.5 and 1135.0 ppm with a mean value of 848.9 ppm. Conclusion The study showed that the CO2 enhanced sweep flag increased the ability of I. ricinus (p < 0001) but not of D. marginatus to be attracted to the flag blanket. PMID:22720872

  13. Red flags to screen for malignancy and fracture in patients with low back pain: systematic review

    PubMed Central

    Williams, Christopher M; Henschke, Nicholas; Hancock, Mark J; Ostelo, Raymond W J G; de Vet, Henrica C W; Macaskill, Petra; Irwig, Les; van Tulder, Maurits W; Koes, Bart W; Maher, Christopher G

    2013-01-01

    Objective To review the evidence on diagnostic accuracy of red flag signs and symptoms to screen for fracture or malignancy in patients presenting with low back pain to primary, secondary, or tertiary care. Design Systematic review. Data sources Medline, OldMedline, Embase, and CINAHL from earliest available up to 1 October 2013. Inclusion criteria Primary diagnostic studies comparing red flags for fracture or malignancy to an acceptable reference standard, published in any language. Review methods Assessment of study quality and extraction of data was conducted by three independent assessors. Diagnostic accuracy statistics and post-test probabilities were generated for each red flag. Results We included 14 studies (eight from primary care, two from secondary care, four from tertiary care) evaluating 53 red flags; only five studies evaluated combinations of red flags. Pooling of data was not possible because of index test heterogeneity. Many red flags in current guidelines provide virtually no change in probability of fracture or malignancy or have untested diagnostic accuracy. The red flags with the highest post-test probability for detection of fracture were older age (9%, 95% confidence interval 3% to 25%), prolonged use of corticosteroid drugs (33%, 10% to 67%), severe trauma (11%, 8% to 16%), and presence of a contusion or abrasion (62%, 49% to 74%). Probability of spinal fracture was higher when multiple red flags were present (90%, 34% to 99%). The red flag with the highest post-test probability for detection of spinal malignancy was history of malignancy (33%, 22% to 46%). Conclusions While several red flags are endorsed in guidelines to screen for fracture or malignancy, only a small subset of these have evidence that they are indeed informative. These findings suggest a need for revision of many current guidelines. PMID:24335669

  14. Experimental investigation of the elastic flag spontaneous flapping in water flow

    NASA Astrophysics Data System (ADS)

    Jia, Yongxia; Jia, Lichao; Su, Zhuang; Zhu, Yiding; Yuan, Huijing; Lee, Cunbiao

    2015-11-01

    The flapping stability and the response of a thin two-dimensional flag of low bending rigidity to the Reynolds number was investigated. The three relevant non-dimensional parameters governing fluid-structure problems that concern the interaction of elastic flags with high-speed fluid flows are the structure-to-fluid mass ratio, the non-dimensional bending rigidity and the Reynolds number. To study the mechanisms of the transition from the periodic flapping to chaotic flapping, we use PIV and flow visualization techniques to obtain the whole flow field around the midspan of the immersed elastic flag interacting with fluid in both periodic and chaotic states. A moving interface detection technique is used to determine the flag position and velocity. Virtual particle images are imposed in the flag region in the PIV algorithm, of which the displacements are evaluated by the flag movement. We find that the value of St is constrained in the narrow range of 0.2 < St < 0.31 based on the flapping amplitude.We find that the transition to chaos occurs at a critical Reynolds number Re = 60800. For the larger Reynolds number, the high-strength vortices are distributed in a detached region away from the free end of the flag during the intermittent snapping events in the chaotic regime.

  15. Evaluation of the automated hematology analyzer Sysmex XT-2000iV™ compared to the ADVIA® 2120 for its use in dogs, cats, and horses: Part I--precision, linearity, and accuracy of complete blood cell count.

    PubMed

    Bauer, Natali; Nakagawa, Julia; Dunker, Cathrin; Failing, Klaus; Moritz, Andreas

    2011-11-01

    The automated laser-based hematology analyzer Sysmex XT-2000iV™ providing a complete blood cell count (CBC) and 5-part differential has been introduced in large veterinary laboratories. The aim of the current study was to determine precision, linearity, and accuracy of the Sysmex analyzer. Reference method for the accuracy study was the laser-based hematology analyzer ADVIA® 2120. For evaluation of accuracy, consecutive fresh blood samples from healthy and diseased cats (n = 216), dogs (n = 314), and horses (n = 174) were included. A low intra-assay coefficient of variation (CV) of approximately 1% was seen for the CBC except platelet count (PLT). An intra-assay CV ranging between 2% and 5.5% was evident for the differential count except for feline and equine monocytes (7.7%) and horse eosinophils (15.7%). Linearity was excellent for white blood cell count (WBC), hematocrit value, red blood cell count (RBC), and PLT. For all evaluated species, agreement was excellent for WBC and RBC, with Spearman rank correlation coefficients (r(s)) ranging from >0.99 to 0.98. Hematocrit value correlated excellently in cats and dogs, whereas for horses, a good correlation was evident. A good correlation between both analyzers was seen in feline and equine PLT (r(s) = 0.89 and 0.92, respectively), whereas correlation was excellent for dogs (r(s) = 0.93). Biases were close to 0 except for mean corpuscular hemoglobin concentration (4.11 to -7.25 mmol/l) and canine PLT (57 × 10(9)/l). Overall, the performance of the Sysmex analyzer was excellent and compared favorably with the ADVIA analyzer.

  16. An Auto-flag Method of Radio Visibility Data Based on Support Vector Machine

    NASA Astrophysics Data System (ADS)

    Hui-mei, Dai; Ying, Mei; Wei, Wang; Hui, Deng; Feng, Wang

    2017-01-01

    The Mingantu Ultrawide Spectral Radioheliograph (MUSER) has entered a test observation stage. After the construction of the data acquisition and storage system, it is urgent to automatically flag and eliminate the abnormal visibility data so as to improve the imaging quality. In this paper, according to the observational records, we create a credible visibility set, and further obtain the corresponding flag model of visibility data by using the support vector machine (SVM) technique. The results show that the SVM is a robust approach to flag the MUSER visibility data, and can attain an accuracy of about 86%. Meanwhile, this method will not be affected by solar activities, such as flare eruptions.

  17. Effect of the hemoglobin-based oxygen carrier HBOC-201 on laboratory instrumentation: cobas integra, chiron blood gas analyzer 840, Sysmex SE-9000 and BCT.

    PubMed

    Wolthuis, A; Peek, D; Scholten, R; Moreira, P; Gawryl, M; Clark, T; Westerhuis, L

    1999-01-01

    As part of a clinical trial, we evaluated the effects of the hemoglobin-based oxygen-carrier (HBOC) HBOC-201 (an ultrapurified, stroma-free bovine hemoglobin product, Biopure, Cambridge, MA, USA) on our routine clinical chemistry analyzer (Cobas Integra, F. Hoffmann-La Roche Ltd, Basel, Switzerland ), blood gas analyzer (Chiron 840, Chiron Diagnostics Corporation, East Walpole, MA, USA), routine hemocytometry analyzer (Sysmex SE-9000, TOA Medical Electronics Co Ltd., Kobe, Japan), hemostasis analyzer (BCT, Dade-Behring, Marburg, Germany) and bloodbanking system (Dia-Med-ID Micro Typing System, DiaMed AG, Cressier, Switzerland). The maximum tested concentration of HBOC-201 was 65 g/l. Of the 27 routine clinical chemistry tests challenged with HBOC-201, bilirubin-direct, creatine kinase MB-fraction (CK-MB), creatine kinase (CK), gamma-glutamyltransferase (GGT), magnesium and uric acid were influenced by even low concentrations of HBOC-201. These tests were excluded from use on the plasma of patients treated with HBOC-201. Since the non-availability of the cardiac marker CK-MB may lead to problems in acute situations, we introduced the qualitative Trop T-test (Boehringer Mannheim), which was not influenced. The applicability of another nine tests was limited by the concentration of the HBOC-201 in the patients' plasma. No interference of HBOC-201 in routine hemocytometry, hemostasis-analysis and red-blood cell agglutination detection (blood-bank tests) was observed. Although immediate patient-care was not compromised, routine use of hemoglobin-based oxygen carriers will have a strong impact on logistical management. The development of robust laboratory tests free from the interference of the pigmented oxygen carriers should therefore precede its introduction into routine transfusion medicine.

  18. Changes in haematology measurements with the Sysmex XT-2000iV during storage of feline blood sampled in EDTA or EDTA plus CTAD.

    PubMed

    Granat, Fanny; Geffré, Anne; Bourgès-Abella, Nathalie; Braun, Jean-Pierre; Trumel, Catherine

    2013-06-01

    In veterinary medicine a complete blood cell count (CBC) cannot always be performed within 24 h as usually recommended, particularly for specimens shipped to a reference laboratory. This raises the question of the stability of the variables, especially in ethylenediamine tetra-acetic acid (EDTA) feline blood specimens, known to be prone to in vitro platelet aggregation. Citrate, theophylline, adenosine and dipyridamole (CTAD) has been reported to limit platelet aggregation in feline blood specimens. The aim of this study was to measure the stability of the haematological variables and the platelet aggregation score in EDTA and EDTA plus CTAD (EDCT) feline blood specimens during 48 h of storage at room temperature. Forty-six feline EDTA and EDCT blood specimens were analysed with a Sysmex XT-2000iV analyser, and the platelet count and score of platelet aggregation were estimated immediately and after 24 and 48 h of storage. A significant increase in mean corpuscular volume, haematocrit, reticulocyte and eosinophil counts, and a significant decrease in mean corpuscular haemoglobin concentration and monocyte count were observed. Haemoglobin, mean corpuscular haemoglobin, and red blood cell, white blood cell, neutrophil and lymphocyte counts remained stable. Changes in reticulocyte indexes with time (low fluorescence ratio, medium fluorescence ratio, high fluorescence ratio and immature reticulocyte fraction) were not significant. Changes were generally more pronounced in EDTA than in EDCT. Platelet aggregation decreased markedly in initially highly aggregated EDTA specimens, and increased slightly in initially non- or mildly-aggregated EDTA or EDCT specimens. Platelet counts increased and decreased, or remained stable, respectively. CTAD can reduce storage-induced changes of the haematological variables in feline samples, thus improving the reliability of a CBC and limiting clinical misinterpretations.

  19. A single exposure to the American flag shifts support toward Republicanism up to 8 months later.

    PubMed

    Carter, Travis J; Ferguson, Melissa J; Hassin, Ran R

    2011-08-01

    There is scant evidence that incidental cues in the environment significantly alter people's political judgments and behavior in a durable way. We report that a brief exposure to the American flag led to a shift toward Republican beliefs, attitudes, and voting behavior among both Republican and Democratic participants, despite their overwhelming belief that exposure to the flag would not influence their behavior. In Experiment 1, which was conducted online during the 2008 U.S. presidential election, a single exposure to an American flag resulted in a significant increase in participants' Republican voting intentions, voting behavior, political beliefs, and implicit and explicit attitudes, with some effects lasting 8 months after the exposure to the prime. In Experiment 2, we replicated the findings more than a year into the current Democratic presidential term. These results constitute the first evidence that nonconscious priming effects from exposure to a national flag can bias the citizenry toward one political party and can have considerable durability.

  20. Artist's rendering of astronaut Neil Armstrong planting U.S. flag on Moon

    NASA Technical Reports Server (NTRS)

    1969-01-01

    Artist's Concept: Apollo 11 astronaut Neil Armstrong, after stepping onto the lunar surface, will plant the United States flag in its soil. The flag will be made of nylone, size 3- by 5 feet on a staff 8 feet long. During flight it will be stowed in two 4-foot sections strapped to the Lunar Module ladder. Armstrong's first assignment after stepping off the ladder is to pull a 'D' ring to start a television camera. The second assignment is to erect the U.S. flag. The flag will appear to be flying in a breeze. This is done with a spring-loaded wire in the nylon cloth. With everything is working normally, this will be observed on live television.

  1. 38. FLAG/ADMIRAL BRIDGE PORT LOOKING TO STARBOARD SHOWING RADAR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    38. FLAG/ADMIRAL BRIDGE - PORT LOOKING TO STARBOARD SHOWING RADAR SCOPE, ADMIRAL'S CHAIR, GYRO REPEATER AND VARIOUS COMMUNICATION SYSTEMS. - U.S.S. HORNET, Puget Sound Naval Shipyard, Sinclair Inlet, Bremerton, Kitsap County, WA

  2. FLAG Simulations of the Elasticity Test Problem of Gavrilyuk et al.

    SciTech Connect

    Kamm, James R.; Runnels, Scott R.; Canfield, Thomas R.; Carney, Theodore C.

    2014-04-23

    This report contains a description of the impact problem used to compare hypoelastic and hyperelastic material models, as described by Gavrilyuk, Favrie & Saurel. That description is used to set up hypoelastic simulations in the FLAG hydrocode.

  3. U.S. BICENTENNIAL EXPOSITION & FINISHED PAINTED AMERICAN FLAG ON VAB

    NASA Technical Reports Server (NTRS)

    1976-01-01

    Finishing touches on the largest American flag ever painted were completed today on the south side of the Vehicle Assembly Building at KSC's Launch Complex 39. The flag was painted as part of 3rd Century America, the U. S. Bicentennial Exposition on Science and Technology to be held here from May 30 through September 7. The flag is located on the western side of the VAB's south wall. Still to be painted is the American Revolution Bicentennial Administration's [ARBA] distinctive emblem. This will be placed on the eastern side of the south wall and should be completed by mid-May. The flag is 209 feet long and 100 feet in width. Each of its 13 red and white bars is nearly 8 and a half feet wide. The ARBA symbol will be 110 feet in diameter.

  4. Navigating a path delineated by colored flags: an approach for a 2011 IGVC requirement

    NASA Astrophysics Data System (ADS)

    Szmatula, Alex; Parrish, Matt; Krishnan, Mohan; Paulik, Mark; Mohammad, Utayba; Luo, Chaomin

    2012-01-01

    In this work, we address a situation presented as a new requirement for the Autonomous Challenge portion of the 2011 Intelligent Ground Vehicle Competition (IGVC). This new requirement is to navigate between red and green colored flags placed within the normal white painted lane lines. The regular vision algorithms had to be enhanced to reliably identify and localize the colored flags, while the Navigation algorithms had to be modified to satisfy the constraints placed on the robot while transiting through the flag region. The challenge in finding a solution was the size of the flags, the possibility of loosing them against the background, as well as their movement in the wind. The attendant possibility of false positives and negatives also needed to be addressed to increase reliability of detection. Preliminary tests on the robot have produced positive results.

  5. Yellow flag scores in a compensable New Zealand cohort suffering acute low back pain

    PubMed Central

    Grimmer-Somers, Karen; Prior, Mathew; Robertson, Jim

    2008-01-01

    Background Despite its high prevalence, most acute low back pain (ALBP) is nonspecific, self-limiting with no definable pathology. Recurrence is prevalent, as is resultant chronicity. Psychosocial factors (yellow flags comprising depression and anxiety, negative pain beliefs, job dissatisfaction) are associated with the development of chronic LBP. Methods A national insurer (Accident Compensation Corporation, New Zealand [NZ]), in conjunction with a NZ primary health organization, piloted a strategy for more effective management of patients with ALBP, by following the NZ ALBP Guideline. The guidelines recommend the use of a psychosocial screening instrument (Yellow Flags Screening Instrument, a derivative of Örebro Musculoskeletal Pain Questionnaire). This instrument was recommended for administration on the second visit to a general medical practitioner (GP). This paper tests whether published cut-points of yellow flag scores to predict LBP claims length and costs were valid in this cohort. Results Data was available for 902 claimants appropriately enrolled into the pilot. 25% claimants consulted the GP once only, and thus were not requested to provide a yellow flag score. Yellow flag scores were provided by 48% claimants who consumed two or more GP services. Approximately 60% LBP presentations resolved within five GP visits. Yellow flag scores were significantly and positively associated with treatment costs and service use, although the association was nonlinear. Claimants with moderate yellow flag scores were similarly likely to incur lengthy claims as claimants with at-risk scores. Discussion Capturing data on psychosocial factors for compensable patients with ALBP has merit in predicting lengthy claims. The validity of the published yellow flag cut-points requires further testing. PMID:21197284

  6. 46 CFR 381.9 - Available U.S.-flag service.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... at U.S. Great Lakes ports, a joint service involving a foreign-flag vessel(s) carrying cargo no farther than a Canadian port(s) or other point(s) on the Gulf of St. Lawrence, with transshipment via a U... point on the Gulf of St. Lawrence and a U.S.-flag leg for the remainder of the voyage. The “fair...

  7. 46 CFR 381.9 - Available U.S.-flag service.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... at U.S. Great Lakes ports, a joint service involving a foreign-flag vessel(s) carrying cargo no farther than a Canadian port(s) or other point(s) on the Gulf of St. Lawrence, with transshipment via a U... point on the Gulf of St. Lawrence and a U.S.-flag leg for the remainder of the voyage. The “fair...

  8. Psychometric analysis of the Systematic Observation of Red Flags for autism spectrum disorder in toddlers.

    PubMed

    Dow, Deanna; Guthrie, Whitney; Stronach, Sheri T; Wetherby, Amy M

    2017-04-01

    The purpose of this study was to examine the utility of the Systematic Observation of Red Flags as an observational level-two screening measure to detect risk for autism spectrum disorder in toddlers when used with a video-recorded administration of the Communication and Symbolic Behavior Scales. Psychometric properties of the Systematic Observation of Red Flags were examined in a sample of 247 toddlers of 16- to 24 months old: 130 with autism spectrum disorder, 61 with developmental delays, and 56 typically developing. Individual items were examined for performance to create an algorithm with improved sensitivity and specificity, yielding a total Composite score and Domain scores for Social Communication and Restricted Repetitive Behaviors. Codes indicating clear symptom presence were collapsed to yield a count of the number of Red Flags for the overall scale and each symptom domain. Results indicated significant group differences with large effects for the Composite, both Domain scores, and Red Flags score, and good discrimination (area under the curve = 0.84-0.87) between autism spectrum disorder and nonspectrum groups for the Composite, Social Communication Domain, and Social Communication Red Flags score. The Systematic Observation of Red Flags provides an observational screening measure for 16- to 24-month-olds with good discrimination, sensitivity, and specificity. A cutoff of 20 on the Composite is recommended to optimally detect autism spectrum disorder risk.

  9. Freestanding Flag-Type Triboelectric Nanogenerator for Harvesting High-Altitude Wind Energy from Arbitrary Directions.

    PubMed

    Zhao, Zhenfu; Pu, Xiong; Du, Chunhua; Li, Linxuan; Jiang, Chunyan; Hu, Weiguo; Wang, Zhong Lin

    2016-02-23

    Wind energy at a high altitude is far more stable and stronger than that near the ground, but it is out of reach of the wind turbine. Herein, we develop an innovative freestanding woven triboelectric nanogenerator flag (WTENG-flag) that can harvest high-altitude wind energy from arbitrary directions. The wind-driven fluttering of the woven unit leads to the current generation by a coupled effect of contact electrification and electrostatic induction. Systematic study is conducted to optimize the structure/material parameters of the WTENG-flag to improve the power output. This 2D WTENG-flag can also be stacked in parallel connections in many layers for a linearly increased output. Finally, a self-powered high-altitude platform with temperature/humidity sensing/telecommunicating capability is demonstrated with the WTENG-flag as a power source. Due to the light weight, low cost, and easy scale-up, this WTENG-flag has great potential for applications in weather/environmental sensing/monitoring systems.

  10. Flexible Tricolor Flag-liked Microribbons Array with Enhanced Conductive Anisotropy and Multifunctionality

    PubMed Central

    Ma, Qianli; Yu, Wensheng; Dong, Xiangting; Yang, Ming; Wang, Jinxian; Liu, Guixia

    2015-01-01

    Anisotropically conductive materials are important components in subminiature devices. However, at this stage, some defects have limited practical applications of them, especially low anisotropic degree and high cost. Here, we report novel tricolor flag-liked microribbons array prepared by electrospinning technique. The tricolor flag-liked microribbons array is composed of parallel microribbons, and each microribbon consists of three different regions, just like tricolor flag. The tricolor flag-liked microribbons array is only electrically conductive in the direction parallel to the microribbons, whereas in the perpendicular and thickness directions are insulative. The electrical conductivity along parallel direction reaches up to 8 orders of magnitude higher than that along perpendicular direction. The degree of anisotropy in present study is increased by 2 orders of magnitude than that of the anisotropically conductive material in references reported before. Besides, other functions can be conveniently assembled into tricolor flag-liked microribbons array to realize multifunctionality. Owing to the high electrical anisotropy and multifunctionality, tricolor flag-liked microribbons array will have important applications. Furthermore, a universal technique to prepare microribbons with three functional regions has been established for fabricating excellent multifunctional materials. PMID:26412500

  11. Special Measurement Clothing and Footwear, Orthopedic Footwear, Guidons, Streamers, and Flags (Supplementation is Permitted at all Levels)

    DTIC Science & Technology

    2007-11-02

    GUIDONS , STREAMERS, AND FLAGS (Supplementation is permitted at all levels.) Headquarters Departments of the Army, Defense Logistic AgencyDepartment of...Special Measurement Clothing and Footwear, Orthopedic Footwear, Guidons , Streamers, and Flags Unclassified 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c...NAVSUPINST 4400.70C/MCO 4400.137A SPECIAL MEASUREMENT CLOTHING AND FOOTWEAR, ORTHOPEDIC FOOTWEAR, GUIDONS , STREAMERS, AND FLAGS (Supplementation is

  12. Why do inverted-flags flap in a uniform steady flow?

    NASA Astrophysics Data System (ADS)

    Sader, John; Cossé, Julia; Kim, Daegyoum; Fan, Boyu; Gharib, Morteza

    2016-11-01

    The dynamics of a cantilevered elastic sheet, with a uniform steady flow impinging on its clamped-end, have been studied widely and provide insight into the stability of flags and biological phenomena. Recent measurements by Kim et al. show that reversing the sheet's orientation, with the flow impinging on its free-edge, dramatically alters its dynamics. In this talk, we use a combination of mathematical theory, scaling analysis and measurement to explore the physical mechanisms driving the observed large-amplitude flapping motion of an inverted-flag. Flapping is found to be periodic predominantly, with a transition to chaos as flow speed increases. These findings have implications to leaf motion and other biological processes, such as the dynamics of individual hairs, because they also can present an inverted-flag configuration. Gordon and Betty Moore Foundation; Ministry of Trade, Industry and Energy, Republic of Korea; Australian Research Council Grants scheme.

  13. Bernard J. Cigrand, DDS: Father of Flag Day and renaissance man.

    PubMed

    Spiegel, Allen D; Kavaler, Florence

    2007-06-01

    Dr. Bernard J. Cigrand is acknowledged as the "Father of Flag Day." He relentlessly continued his activities for more than sixty years to have June 14 designated for the national observance of the birth of the American flag. That finally occurred in 1948, seventeen years after his death, when President Harry S. Truman signed a Congressional Act into law. However, the law designated a voluntary observance but did not create a legal national holiday. In addition to his fervent passion for Flag Day, Cigrand undertook a variety of other initiatives He was a practicing dentist, the dean of a dental school, an investigative journalist, an expert on heraldry and seals, a lecturer and an author of books. Despite all his achievements, Cigrand is more widely known in the European country from where his parents emigrated to the United States in 1852 - Luxembourg, than in the United States.

  14. The flagellar protein FLAG1/SMP1 is a candidate for Leishmania-sand fly interaction.

    PubMed

    Di-Blasi, Tatiana; Lobo, Amanda R; Nascimento, Luanda M; Córdova-Rojas, Jose L; Pestana, Karen; Marín-Villa, Marcel; Tempone, Antonio J; Telleria, Erich L; Ramalho-Ortigão, Marcelo; McMahon-Pratt, Diane; Traub-Csekö, Yara M

    2015-03-01

    Leishmaniasis is a serious problem that affects mostly poor countries. Various species of Leishmania are the agents of the disease, which take different clinical manifestations. The parasite is transmitted by sandflies, predominantly from the Phlebotomus genus in the Old World and Lutzomyia in the New World. During development in the gut, Leishmania must survive various challenges, which include avoiding being expelled with blood remnants after digestion. It is believed that attachment to the gut epithelium is a necessary step for vector infection, and molecules from parasites and sand flies have been implicated in this attachment. In previous work, monoclonal antibodies were produced against Leishmania. Among these an antibody was obtained against Leishmania braziliensis flagella, which blocked the attachment of Leishmania panamensis flagella to Phlebotomus papatasi guts. The protein recognized by this antibody was identified and named FLAG1, and the complete FLAG1 gene sequence was obtained. This protein was later independently identified as a small, myristoylated protein and called SMP1, so from now on it will be denominated FLAG1/SMP1. The FLAG1/SMP1 gene is expressed in all developmental stages of the parasite, but has higher expression in promastigotes. The anti-FLAG1/SMP1 antibody recognized the flagellum of all Leishmania species tested and generated the expected band by western blots. This antibody was used in attachment and infection blocking experiments. Using the New World vector Lutzomyia longipalpis and Leishmania infantum chagasi, no inhibition of attachment ex vivo or infection in vivo was seen. On the other hand, when the Old World vectors P. papatasi and Leishmania major were used, a significant decrease of both attachment and infection were seen in the presence of the antibody. We propose that FLAG1/SMP1 is involved in the attachment/infection of Leishmania in the strict vector P. papatasi and not the permissive vector L. longipalpis.

  15. Multi-Level Pre-Correlation RFI Flagging for Real-Time Implementation on UniBoard

    NASA Astrophysics Data System (ADS)

    Dumez-Viou, Cédric; Weber, Rodolphe; Ravier, Philippe

    Because of the denser active use of the spectrum, and because of radio telescopes higher sensitivity, radio frequency interference (RFI) mitigation has become a sensitive topic for current and future radio telescope designs. Even if quite sophisticated approaches have been proposed in the recent years, the majority of RFI mitigation operational procedures are based on post-correlation corrupted data flagging. Moreover, given the huge amount of data delivered by current and next generation radio telescopes, all these RFI detection procedures have to be at least automatic and, if possible, real-time. In this paper, the implementation of a real-time pre-correlation RFI detection and flagging procedure into generic high-performance computing platforms based on field programmable gate arrays (FPGA) is described, simulated and tested. One of these boards, UniBoard, developed under a Joint Research Activity in the RadioNet FP7 European programme is based on eight FPGAs interconnected by a high speed transceiver mesh. It provides up to 4 TMACs with ®Altera Stratix IV FPGA and 160 Gbps data rate for the input data stream. The proposed concept is to continuously monitor the data quality at different stages in the digital preprocessing pipeline between the antennas and the correlator, at the station level and the core level. In this way, the detectors are applied at stages where different time-frequency resolutions can be achieved and where the interference-to-noise ratio (INR) is maximum right before any dilution of RFI characteristics by subsequent channelizations or signal recombinations. The detection decisions could be linked to a RFI statistics database or could be attached to the data for later stage flagging. Considering the high in-out data rate in the pre-correlation stages, only real-time and go-through detectors (i.e. no iterative processing) can be implemented. In this paper, a real-time and adaptive detection scheme is described. An ongoing case study has been

  16. (U) A Gruneisen Equation of State for TPX. Application in FLAG

    SciTech Connect

    Fredenburg, David A.; Aslam, Tariq Dennis; Bennett, Langdon Stanford

    2015-11-02

    A Gruneisen equation of state (EOS) is developed for the polymer TPX (poly 4-methyl-1-pentene) within the LANL hydrocode FLAG. Experimental shock Hugoniot data for TPX is fit to a form of the Gruneisen EOS, and the necessary parameters for implementing the TPX EOS in FLAG are presented. The TPX EOS is further validated through one-dimensional simulations of recent double-shock experiments, and a comparison is made between the new Gruneisen EOS for TPX and the EOS representation for TPX used in the LANL Common Model.

  17. Astronaut David Scott gives salute beside U.S. flag during EVA

    NASA Technical Reports Server (NTRS)

    1971-01-01

    Astronaut David R. Scott, commander, gives a military salute while standing beside the deployed U.S. flag during the Apollo 15 lunar surface extravehicular activity (EVA) at the Hadley-Apennine landing site. The flag was deployed toward the end of EVA-2. The Lunar Module 'Falcon' is partially visible on the right. Hadley Delta in the background rises approximately 4,000 meters (about 13,124 feet) above the plain. The base of the mountain is approximately 5 kilometers (about 3 statute miles) away. This photograph was taken by Astronaut James B. Irwin, Lunar Module pilot.

  18. Astronaut James Irwin gives salute beside U.S. flag during EVA

    NASA Technical Reports Server (NTRS)

    1971-01-01

    Astronaut James B. Irwin, lunar module pilot, gives a military salute while standing beside the deployed U.S. flag during the Apollo 15 lunar surface extravehicular activity (EVA) at the Hadley-Apennine landing site. The flag was deployed toward the end of EVA-2. The Lunar Module 'Falcon' is partially visible on the right. Hadley Delta in the background rises approximately 4,000 meters (about 13,124 feet) above the plain. The base of the mountain is approximately 5 kilometers (about 3 statute miles) away. This photograph was taken by Astronaut David R. Scott, Apollo 15 commander.

  19. AsteroFLAG: First results from hare-and-hounds Exercise #1

    NASA Astrophysics Data System (ADS)

    Chaplin, W. J.; Appourchaux, T.; Arentoft, T.; Ballot, J.; Christensen-Dalsgaard, J.; Creevey, O. L.; Elsworth, Y.; Fletcher, S. T.; García, R. A.; Houdek, G.; Jiménez-Reyes, S. J.; Kjeldsen, H.; New, R.; Régulo, C.; Salabert, D.; Sekii, T.; Sousa, S. G.; Toutain, T.; rest of asteroFLAG Group

    2008-06-01

    We report on initial results from the first phase of Exercise #1 of the asteroFLAG hare and hounds. The asteroFLAG group is helping to prepare for the asteroseismology component of NASA's Kepler mission, and the first phase of Exercise #1 is concerned with testing extraction of estimates of the large and small frequency spacings of the low-degree p modes from Kepler-like artificial data. These seismic frequency spacings will provide key input for complementing the exoplanet search data.

  20. solarFLAG hare and hounds: estimation of p-mode frequencies from Sun-as-star helioseismology data

    NASA Astrophysics Data System (ADS)

    Jiménez-Reyes, S. J.; Chaplin, W. J.; García, R. A.; Appourchaux, T.; Baudin, F.; Boumier, P.; Elsworth, Y.; Fletcher, S. T.; Lazrek, M.; Leibacher, J. W.; Lochard, J.; New, R.; Régulo, C.; Salabert, D.; Toutain, T.; Verner, G. A.; Wachter, R.

    2008-10-01

    We report on the results of the latest solarFLAG hare-and-hounds exercise, which was concerned with testing methods for extraction of frequencies of low-degree solar p modes from data collected by Sun-as-a-star observations. We have used the new solarFLAG simulator, which includes the effects of correlated mode excitation and correlations with background noise, to make artificial time-series data that mimic Doppler velocity observations of the Sun-as-a-star. The correlations give rise to asymmetry of mode peaks in the frequency power spectrum. 10 members of the group (the hounds) applied their `peak-bagging' codes to a 3456-d data set, and the estimated mode frequencies were returned to the hare (who was WJC) for comparison. Analysis of the results reveals a systematic bias in the estimated frequencies of modes above ~1.8mHz. The bias is negative, meaning the estimated frequencies systematically underestimate the input frequencies. We identify two sources that are the dominant contributions to the frequency bias. Both sources involve failure to model accurately subtle aspects of the observed power spectral density in the part (window) of the frequency power spectrum that is being fitted. One source of bias arises from a failure to account for the power spectral density coming from all those modes whose frequencies lie outside the fitting windows. The other source arises from a failure to account for the power spectral density of the weak l = 4 and 5 modes, which are often ignored in Sun-as-a-star analysis. The Sun-as-a-star peak-bagging codes need to allow for both sources, otherwise the frequencies are likely to be biased.

  1. 50 CFR 216.46 - U.S. citizens on foreign flag vessels operating under the International Dolphin Conservation...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 10 2013-10-01 2013-10-01 false U.S. citizens on foreign flag vessels operating under the International Dolphin Conservation Program. 216.46 Section 216.46 Wildlife and Fisheries....46 U.S. citizens on foreign flag vessels operating under the International Dolphin...

  2. 50 CFR 216.46 - U.S. citizens on foreign flag vessels operating under the International Dolphin Conservation...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 10 2012-10-01 2012-10-01 false U.S. citizens on foreign flag vessels operating under the International Dolphin Conservation Program. 216.46 Section 216.46 Wildlife and Fisheries....46 U.S. citizens on foreign flag vessels operating under the International Dolphin...

  3. 50 CFR 216.46 - U.S. citizens on foreign flag vessels operating under the International Dolphin Conservation...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false U.S. citizens on foreign flag vessels operating under the International Dolphin Conservation Program. 216.46 Section 216.46 Wildlife and Fisheries....46 U.S. citizens on foreign flag vessels operating under the International Dolphin...

  4. 50 CFR 216.46 - U.S. citizens on foreign flag vessels operating under the International Dolphin Conservation...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 10 2014-10-01 2014-10-01 false U.S. citizens on foreign flag vessels operating under the International Dolphin Conservation Program. 216.46 Section 216.46 Wildlife and Fisheries....46 U.S. citizens on foreign flag vessels operating under the International Dolphin...

  5. 50 CFR 216.46 - U.S. citizens on foreign flag vessels operating under the International Dolphin Conservation...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false U.S. citizens on foreign flag vessels operating under the International Dolphin Conservation Program. 216.46 Section 216.46 Wildlife and Fisheries....46 U.S. citizens on foreign flag vessels operating under the International Dolphin...

  6. 76 FR 1665 - Stakeholder Meetings Regarding the U.S.-Flag Great Lakes Fleet Revitalization Study; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-11

    ... Maritime Administration Stakeholder Meetings Regarding the U.S.-Flag Great Lakes Fleet Revitalization Study... public listening- session meetings it is conducting to gather data and comments to inform the Maritime Administration's U.S.-Flag Great Lakes Fleet Revitalization Study. MARAD inadvertently listed the incorrect...

  7. Switchgrass (Panicum virgatum L) flag leaf transcriptomes reveal molecular signatures of leaf development, senescence, and mineral dynamics

    Technology Transfer Automated Retrieval System (TEKTRAN)

    We provide the first comprehensive transcriptomic inspection of switchgrass flag leaf development. Flag leaves were collected from field grown switchgrass plants at five plant developmental stages: heading, anthesis, early and late seed development, and at physiological maturity and analyzed by RNA...

  8. 14 CFR 121.467 - Flight attendant duty period limitations and rest requirements: Domestic, flag, and supplemental...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... time, using Coordinated Universal Time or local time, that begins at midnight and ends 24 hours later... domestic, flag, or supplemental operations. The time is calculated using either Coordinated Universal Time..., FLAG, AND SUPPLEMENTAL OPERATIONS Aircraft Dispatcher Qualifications and Duty Time...

  9. 14 CFR 121.467 - Flight attendant duty period limitations and rest requirements: Domestic, flag, and supplemental...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... time, using Coordinated Universal Time or local time, that begins at midnight and ends 24 hours later... domestic, flag, or supplemental operations. The time is calculated using either Coordinated Universal Time..., FLAG, AND SUPPLEMENTAL OPERATIONS Aircraft Dispatcher Qualifications and Duty Time...

  10. 46 CFR 39.1015 - Foreign-flagged tank vessel certification procedures for vapor control system designs-TB/ALL.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... certification by the classification society that classifies vessels under their foreign flags to the Marine... requirements of this part, the Officer in Charge, Marine Inspection (OCMI) will endorse the vessel's... 46 Shipping 1 2014-10-01 2014-10-01 false Foreign-flagged tank vessel certification procedures...

  11. 46 CFR 39.1015 - Foreign-flagged tank vessel certification procedures for vapor control system designs-TB/ALL.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... certification by the classification society that classifies vessels under their foreign flags to the Marine... requirements of this part, the Officer in Charge, Marine Inspection (OCMI) will endorse the vessel's... 46 Shipping 1 2013-10-01 2013-10-01 false Foreign-flagged tank vessel certification procedures...

  12. 22 CFR 201.15 - U.S. flag vessel shipping requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... reasonable rates for such vessels: (1) At least fifty percent (50%) of the gross tonnage (computed separately... vessels are available at fair and reasonable rates for such vessels. U.S. flag dry cargo liners whose... for any specific shipment of commodities at fair and reasonable rates. A determination that U.S....

  13. 76 FR 39885 - Risk-Based Targeting of Foreign Flagged Mobile Offshore Drilling Units (MODUs)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-07

    ... SECURITY Coast Guard Risk-Based Targeting of Foreign Flagged Mobile Offshore Drilling Units (MODUs) AGENCY... Drilling Units (MODUs). This policy letter announces changes to the Coast Guard's system used to prioritize... drilling unit (MODU) must undergo a Coast Guard Certificate of Compliance (COC) examination in order...

  14. The Ultimate Flag Games Curriculum: An Answer to a Participation Problem

    ERIC Educational Resources Information Center

    Bell, Martie

    2011-01-01

    In response to a lack of active participation by students in physical education, the Ultimate Flag Games curriculum was created and has thrived in the decades since its inception. The curriculum has been successful at the middle school, high school, and higher education levels. This article introduced the curriculum, different games, and rules and…

  15. 40 CFR 158.34 - Flagging of studies for potential adverse effects.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    .... Table—Flagging Criteria Study Type(s) Guideline No. Criteria: Treated animals show any of the following... females at any dose level, compared to concurrent control animals of the same sex; or 2 An increase in any type of uncommon or rare neoplasms in any test group, males or females animals at any dose...

  16. Dynamic Black-Level Correction and Artifact Flagging in the Kepler Data Pipeline

    NASA Technical Reports Server (NTRS)

    Clarke, B. D.; Kolodziejczak, J. J.; Caldwell, D. A.

    2013-01-01

    Instrument-induced artifacts in the raw Kepler pixel data include time-varying crosstalk from the fine guidance sensor (FGS) clock signals, manifestations of drifting moiré pattern as locally correlated nonstationary noise and rolling bands in the images which find their way into the calibrated pixel time series and ultimately into the calibrated target flux time series. Using a combination of raw science pixel data, full frame images, reverse-clocked pixel data and ancillary temperature data the Keplerpipeline models and removes the FGS crosstalk artifacts by dynamically adjusting the black level correction. By examining the residuals to the model fits, the pipeline detects and flags spatial regions and time intervals of strong time-varying blacklevel (rolling bands ) on a per row per cadence basis. These flags are made available to downstream users of the data since the uncorrected rolling band artifacts could complicate processing or lead to misinterpretation of instrument behavior as stellar. This model fitting and artifact flagging is performed within the new stand-alone pipeline model called Dynablack. We discuss the implementation of Dynablack in the Kepler data pipeline and present results regarding the improvement in calibrated pixels and the expected improvement in cotrending performances as a result of including FGS corrections in the calibration. We also discuss the effectiveness of the rolling band flagging for downstream users and illustrate with some affected light curves.

  17. 48 CFR 52.247-64 - Preference for Privately Owned U.S.-Flag Commercial Vessels.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 52.247-64 Preference for Privately Owned U.S.-Flag Commercial Vessels... acquisition of commercial items unless— (i) This contract is— (A) A contract or agreement for...

  18. 22 CFR 201.15 - U.S. flag vessel shipping requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... COMMODITY TRANSACTIONS FINANCED BY USAID Conditions Governing the Eligibility of Procurement Transactions... and tankers shall be achieved for each quantitative unit of cargo. A quantitative unit of cargo is the... determined that at least 50% of the quantitative unit will move on U.S. flag vessels, to the extent that...

  19. Phloem transport of arsenic species from flag leaf to grain during grain filling

    PubMed Central

    Carey, Anne-Marie; Norton, Gareth J.; Deacon, Claire; Scheckel, Kirk G.; Lombi, Enzo; Punshon, Tracy; Guerinot, Mary Lou; Lanzirotti, Antonio; Newville, Matt; Choi, Yongseong; Price, Adam H.; Meharg, Andrew A.

    2013-01-01

    Summary Strategies to reduce arsenic in rice grain, below levels that represent a serious human health concern, require that the mechanisms of arsenic accumulation within grain be established. Therefore, re-translocation of arsenic species from flag leaves into filling rice grain was investigated.Arsenic species were delivered through cut flag leaves during grain fill. Spatial unloading within grains was investigated using synchrotron X-ray fluorescence (SXRF) microtomography. Additionally, the effect of germanic acid (a silicic acid analogue) on grain arsenic accumulation in arsenite treated panicles was examined.Dimethylarsinic acid (DMA) and monomethylarsonic acid (MMA) were extremely efficiently re-translocated from flag leaves to rice grain; arsenate was poorly re-translocated, and was rapidly reduced to arsenite within flag leaves; arsenite displayed no re-translocation. Within grains, DMA rapidly dispersed while MMA and inorganic arsenic remained close to the entry point. Germanic acid addition did not affect grain arsenic in arsenite treated panicles. 3D SXRF microtomography gave further information on arsenite localization in the ovular vascular trace (OVT) of rice grains.These results demonstrate that inorganic arsenic is poorly re-mobilized, while organic species are readily re-mobilized, from leaves to grain. Stem translocation of inorganic arsenic may not rely solely on silicic acid transporters. PMID:21658183

  20. Phloem Transport Of Arsenic Species From Flag Leaf To Grain During Grain Filling

    EPA Science Inventory

    Strategies to reduce arsenic (As) in rice grain, below concentrations that represent a serious human health concern, require that the mechanisms of As accumulation within grain be established. Therefore, retranslocation of As species from flag leaves into filling rice grain was ...

  1. 14 CFR 121.641 - Fuel supply: Nonturbine and turbo-propeller-powered airplanes: Flag operations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Fuel supply: Nonturbine and turbo-propeller-powered airplanes: Flag operations. 121.641 Section 121.641 Aeronautics and Space FEDERAL AVIATION... Flight Release Rules § 121.641 Fuel supply: Nonturbine and turbo-propeller-powered airplanes:...

  2. 14 CFR 121.641 - Fuel supply: Nonturbine and turbo-propeller-powered airplanes: Flag operations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Fuel supply: Nonturbine and turbo-propeller-powered airplanes: Flag operations. 121.641 Section 121.641 Aeronautics and Space FEDERAL AVIATION... Flight Release Rules § 121.641 Fuel supply: Nonturbine and turbo-propeller-powered airplanes:...

  3. Raising FLAGS: Renewing Core French at the Pre-Service Teacher Level

    ERIC Educational Resources Information Center

    Carr, Wendy

    2010-01-01

    A new program for core French teacher candidates called FLAGS (French Language and Global Studies) was established at the University of British Columbia (UBC) in 2007. The program is intended for those who are keen to teach core French and possess rudimentary proficiency in the language but may not necessarily have the same proficiency or prior…

  4. 14 CFR 121.99 - Communications facilities-domestic and flag operations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Communications facilities-domestic and flag operations. 121.99 Section 121.99 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... system must be able to provide immediate satellite-based voice communications of...

  5. 78 FR 36311 - Flag Recognition Benefit for Fallen Federal Civilian Employees

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-17

    ... Regulatory Commission may furnish flags on behalf of employees who die of injuries incurred in connection... die of certain injuries incurred in connection with their employment. These regulations also provide... benefit. The employee's death must be the result of injuries incurred in connection with his or...

  6. An unusual case of seed dispersal in an invasive aquatic; yellow flag iris (Iris pseudacorus)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Understanding reproductive mode of invasive plants can help managers plan more efficacious control. Invasive aquatics typically reproduce primarily through vegetative means. Yellow flag iris is an invasive plant species often growing as an emergent aquatic. There have been contradictory reports of i...

  7. 14 CFR 121.555 - Compliance with approved routes and limitations: Domestic and flag operations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Compliance with approved routes and... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR CARRIERS AND OPERATORS FOR COMPENSATION OR HIRE... Operations § 121.555 Compliance with approved routes and limitations: Domestic and flag operations. No...

  8. Constructing and Validating the Foreign Language Attitudes and Goals Survey (FLAGS)

    ERIC Educational Resources Information Center

    Cid, Eva; Granena, Gisela; Tragant, Elsa

    2009-01-01

    The present study describes the process that was followed in the construction and validation of the foreign language attitudes and goals survey (FLAGS), a new questionnaire based on qualitative data from Tragant and Munoz [Tragant, Munoz, C., 2000. "La motivacion y su relacion con la edad en un contexto escolar de aprendizaje de una lengua…

  9. 46 CFR 154.22 - Foreign flag vessel: Certificate of Compliance endorsement application.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... vessel that does not meet § 154.12 (b), (c), or (d)— (i) A certification from a classification society... by the Commanding Officer, Marine Safety Center to determine whether or not the vessel meets this... 46 Shipping 5 2012-10-01 2012-10-01 false Foreign flag vessel: Certificate of...

  10. 46 CFR 154.22 - Foreign flag vessel: Certificate of Compliance endorsement application.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... classification society that the vessel— (A) Has enhanced grades of steel meeting § 154.170 (b)(1) and (b)(2) for... 46 Shipping 5 2014-10-01 2014-10-01 false Foreign flag vessel: Certificate of Compliance... (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING...

  11. 46 CFR 154.22 - Foreign flag vessel: Certificate of Compliance endorsement application.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... classification society that the vessel— (A) Has enhanced grades of steel meeting § 154.170 (b)(1) and (b)(2) for... 46 Shipping 5 2013-10-01 2013-10-01 false Foreign flag vessel: Certificate of Compliance... (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING...

  12. 46 CFR 154.22 - Foreign flag vessel: Certificate of Compliance endorsement application.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... vessel that does not meet § 154.12 (b), (c), or (d)— (i) A certification from a classification society... by the Commanding Officer, Marine Safety Center to determine whether or not the vessel meets this... 46 Shipping 5 2011-10-01 2011-10-01 false Foreign flag vessel: Certificate of...

  13. 14 CFR § 1221.113 - Use of the NASA Flags.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Use of the NASA Flags. § 1221.113 Section § 1221.113 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION THE NASA SEAL AND OTHER DEVICES, AND THE CONGRESSIONAL SPACE MEDAL OF HONOR NASA Seal, NASA Insignia, NASA Logotype,...

  14. 14 CFR § 1221.106 - Establishment of the NASA Flag.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Establishment of the NASA Flag. § 1221.106 Section § 1221.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION THE NASA SEAL AND OTHER DEVICES, AND THE CONGRESSIONAL SPACE MEDAL OF HONOR NASA Seal, NASA Insignia, NASA Logotype,...

  15. Flagging versus dragging as sampling methods for nymphal Ixodes scapularis (Acari: Ixodidae)

    USGS Publications Warehouse

    Rulison, Eric L.; Kuczaj, Isis; Pang, Genevieve; Hickling, Graham J.; Tsao, Jean I.; Ginsberg, Howard S.

    2013-01-01

    The nymphal stage of the blacklegged tick, Ixodes scapularis (Acari: Ixodidae), is responsible for most transmission of Borrelia burgdorferi, the etiologic agent of Lyme disease, to humans in North America. From 2010 to fall of 2012, we compared two commonly used techniques, flagging and dragging, as sampling methods for nymphal I. scapularis at three sites, each with multiple sampling arrays (grids), in the eastern and central United States. Flagging and dragging collected comparable numbers of nymphs, with no consistent differences between methods. Dragging collected more nymphs than flagging in some samples, but these differences were not consistent among sites or sampling years. The ratio of nymphs collected by flagging vs dragging was not significantly related to shrub density, so habitat type did not have a strong effect on the relative efficacy of these methods. Therefore, although dragging collected more ticks in a few cases, the numbers collected by each method were so variable that neither technique had a clear advantage for sampling nymphal I. scapularis.

  16. Immunohistochemical Detection of FLAG-Tagged Endogenous Proteins in Knock-In Mice

    PubMed Central

    Newton, Kim; Chu, Felix; Webster, Joshua D.; French, Dorothy M.

    2015-01-01

    With recent advances in immunohistochemical (IHC) techniques, immunohistochemistry now plays a more important role in research, especially in mouse models where characterization of cellular patterns of protein expression has become critical. Even with these recent advances, a paucity of IHC quality antibodies for some proteins still exists. To address this, we have developed a novel IHC assay that utilizes a commercially available goat anti-DDDDK peptide polyclonal antibody on paraffin-embedded tissues from knock-in mice expressing proteins of interest tagged with a 3×FLAG epitope at physiologically relevant levels. Focusing on two 3×FLAG-tagged proteins for which specific antibodies were available, USP48 and RIPK3, we were able to validate our anti-DDDDK assay by comparing the IHC directed against the actual proteins to the anti-DDDDK IHC assay, which recognizes the FLAG epitope. We were also able to detect a third 3×FLAG-tagged protein, BAP1, for which quality reagents were not available. This universal IHC method will enable researchers to characterize the expression patterns of proteins of interest when specific antibodies are lacking. PMID:25575566

  17. Phloem Transport of Arsenic Species from Flag Leaf to Grain During Grain Filling

    SciTech Connect

    A Carey; G Norton; C Deacon; K Scheckel; E Lombi; T Punshon; M Guerinot; A Lanzirotti; M Newville; et al.

    2011-12-31

    Strategies to reduce arsenic (As) in rice grain, below concentrations that represent a serious human health concern, require that the mechanisms of As accumulation within grain be established. Therefore, retranslocation of As species from flag leaves into filling rice grain was investigated. Arsenic species were delivered through cut flag leaves during grain fill. Spatial unloading within grains was investigated using synchrotron X-ray fluorescence (SXRF) microtomography. Additionally, the effect of germanic acid (a silicic acid analog) on grain As accumulation in arsenite-treated panicles was examined. Dimethylarsinic acid (DMA) and monomethylarsonic acid (MMA) were extremely efficiently retranslocated from flag leaves to rice grain; arsenate was poorly retranslocated, and was rapidly reduced to arsenite within flag leaves; arsenite displayed no retranslocation. Within grains, DMA rapidly dispersed while MMA and inorganic As remained close to the entry point. Germanic acid addition did not affect grain As in arsenite-treated panicles. Three-dimensional SXRF microtomography gave further information on arsenite localization in the ovular vascular trace (OVT) of rice grains. These results demonstrate that inorganic As is poorly remobilized, while organic species are readily remobilized, from leaves to grain. Stem translocation of inorganic As may not rely solely on silicic acid transporters.

  18. Phloem transport of arsenic species from flag leaf to grain during grain filling

    SciTech Connect

    Carey, Anne-Marie; Norton, Gareth J.; Deacon, Claire; Scheckel, Kirk G.; Lombi, Enzo; Punshon, Tracy; Guerinot, Mary Lou; Lanzirotti, Antonio; Newville, Matt; Choi, Yongseong; Price, Adam H.; Meharg, Andrew A.

    2011-09-20

    Strategies to reduce arsenic (As) in rice grain, below concentrations that represent a serious human health concern, require that the mechanisms of As accumulation within grain be established. Therefore, retranslocation of As species from flag leaves into filling rice grain was investigated. Arsenic species were delivered through cut flag leaves during grain fill. Spatial unloading within grains was investigated using synchrotron X-ray fluorescence (SXRF) microtomography. Additionally, the effect of germanic acid (a silicic acid analog) on grain As accumulation in arsenite-treated panicles was examined. Dimethylarsinic acid (DMA) and monomethylarsonic acid (MMA) were extremely efficiently retranslocated from flag leaves to rice grain; arsenate was poorly retranslocated, and was rapidly reduced to arsenite within flag leaves; arsenite displayed no retranslocation. Within grains, DMA rapidly dispersed while MMA and inorganic As remained close to the entry point. Germanic acid addition did not affect grain As in arsenite-treated panicles. Three-dimensional SXRF microtomography gave further information on arsenite localization in the ovular vascular trace (OVT) of rice grains. These results demonstrate that inorganic As is poorly remobilized, while organic species are readily remobilized, from leaves to grain. Stem translocation of inorganic As may not rely solely on silicic acid transporters.

  19. 77 FR 72712 - Identity Theft Red Flags and Address Discrepancies Under the Fair and Accurate Credit...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-06

    ... CFR Part 681 RIN 3084-AA94 Identity Theft Red Flags and Address Discrepancies Under the Fair and... ``financial institutions'' and ``creditors'' to develop and implement a written identity theft program to identify, detect, and respond to possible risks of identity theft relevant to them. \\1\\ 72 FR 63718 (Nov....

  20. 14 CFR 121.607 - Communication and navigation facilities: Domestic and flag operations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and..., no person may dispatch an airplane over an approved route or route segment unless the communication... holder may dispatch an airplane over that route or route segment if the pilot in command and...

  1. 14 CFR 121.607 - Communication and navigation facilities: Domestic and flag operations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and..., no person may dispatch an airplane over an approved route or route segment unless the communication... holder may dispatch an airplane over that route or route segment if the pilot in command and...

  2. 14 CFR 121.607 - Communication and navigation facilities: Domestic and flag operations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and..., no person may dispatch an airplane over an approved route or route segment unless the communication... holder may dispatch an airplane over that route or route segment if the pilot in command and...

  3. 14 CFR 121.607 - Communication and navigation facilities: Domestic and flag operations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and..., no person may dispatch an airplane over an approved route or route segment unless the communication... holder may dispatch an airplane over that route or route segment if the pilot in command and...

  4. 14 CFR 121.607 - Communication and navigation facilities: Domestic and flag operations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Dispatching and..., no person may dispatch an airplane over an approved route or route segment unless the communication... holder may dispatch an airplane over that route or route segment if the pilot in command and...

  5. Potential synergy between the Ionospheric Disturbance Flag and NeQuick-G for single frequency users

    NASA Astrophysics Data System (ADS)

    Aragon-Angel, Angela; Fortuny, Joaquim

    2016-04-01

    The document describing the particular ionospheric model developed for the Galileo satellite navigation system has been very recently released, the official Ionospheric Correction Algorithm for Galileo Single Frequency Users document (from here on-wards named Galileo-Iono), available at www.gsc-europa.eu/system/files/galileo_documents/Galileo_Ionospheric_Model.pdf. This publication allows GNSS receiver manufacturers to start the implementation of the specific algorithm targeted for their Galileo related products in order to be compliant with the Galileo system. As indicated in the Galileo OS SIS ICD, among the parameters that are broadcast in the Galileo navigation message, parameters that are sent within both F/NAV and I/NAV, one can find five Ionospheric Disturbance Flags for Regions 1 to 5 (SF1, SF2, SF3, SF4 and SF5). Nevertheless, in the current version of the model presented in the Galileo-Iono document, the Ionospheric Disturbance flags are "not used" within the Galileo ionospheric correction calculation. In this work, a potential approach to account for this information is being investigated. This plan includes the update of the Galileo ionospheric, NeQuick-G, correction model by specifying the use of these flags. Hence a customized version of the NeQuick-G model has been developed and tested. Specific scenarios will be considered to test whether this approach of considering the added value information of the Ionospheric Disturbance Flags is translated into the positioning domain. In order to assess the improvement obtained using the proposed approach five stations displaced in the five regions are used. Different days of data have been collected in nominal and disturbed conditions; the evaluation is carried out comparing the performance of the proposed approach with respect to the classical approach. The benefits of the use of the disturbance flags information are evaluated comparing the performance in similar geometry conditions.

  6. 7 CFR 2.8 - Delegations of authority to agency heads to order that the United States flag be flown at half...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... the United States flag be flown at half-staff. 2.8 Section 2.8 Agriculture Office of the Secretary of... heads to order that the United States flag be flown at half-staff. Pursuant to section 5 of Proclamation... order that the United States flag shall be flown at half-staff on buildings and grounds under his or...

  7. 7 CFR 2.8 - Delegations of authority to agency heads to order that the United States flag be flown at half...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... the United States flag be flown at half-staff. 2.8 Section 2.8 Agriculture Office of the Secretary of... heads to order that the United States flag be flown at half-staff. Pursuant to section 5 of Proclamation... order that the United States flag shall be flown at half-staff on buildings and grounds under his or...

  8. 7 CFR 2.8 - Delegations of authority to agency heads to order that the United States flag be flown at half...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the United States flag be flown at half-staff. 2.8 Section 2.8 Agriculture Office of the Secretary of... heads to order that the United States flag be flown at half-staff. Pursuant to section 5 of Proclamation... order that the United States flag shall be flown at half-staff on buildings and grounds under his or...

  9. 7 CFR 2.8 - Delegations of authority to agency heads to order that the United States flag be flown at half...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... the United States flag be flown at half-staff. 2.8 Section 2.8 Agriculture Office of the Secretary of... heads to order that the United States flag be flown at half-staff. Pursuant to section 5 of Proclamation... order that the United States flag shall be flown at half-staff on buildings and grounds under his or...

  10. 7 CFR 2.8 - Delegations of authority to agency heads to order that the United States flag be flown at half...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... the United States flag be flown at half-staff. 2.8 Section 2.8 Agriculture Office of the Secretary of... heads to order that the United States flag be flown at half-staff. Pursuant to section 5 of Proclamation... order that the United States flag shall be flown at half-staff on buildings and grounds under his or...

  11. Evaluation of the automated hematology analyzer Sysmex XT-2000iV ™ compared to the ADVIA ® 2120 for its use in dogs, cats, and horses. Part II: Accuracy of leukocyte differential and reticulocyte count, impact of anticoagulant and sample aging.

    PubMed

    Bauer, Natali; Nakagawa, Julia; Dunker, Cathrin; Failing, Klaus; Moritz, Andreas

    2012-01-01

    The automated laser-based hematology analyzer Sysmex XT-2000iV™ provides a 5-part differential count and specific cytograms that are of great interest for large veterinary laboratories. The aim of the study was to validate the Sysmex XT-2000iV compared to the laser-based hematology analyzer ADVIA® 2120 and manual differential in dogs, cats, and horses as well as the impact of anticoagulant (heparin, ethylenediamine tetra-acetic acid [EDTA], and citrate) and storage at 22°C and 4°C. Consecutive fresh K(3)-EDTA blood samples from 216 cats, 314 dogs, and 174 horses were included. The impact of anticoagulant and sample storage was assessed in specimens obtained from an additional 9 cats, 10 dogs, and 10 horses. Agreement between both analyzers was excellent to good except for monocytes and canine reticulocytes. Spearman rank correlation coefficients (r (s)) between Sysmex XT-2000iV and manual differential were good to fair and ranged from 0.91 (cat lymphocytes) to 0.44 (cat monocytes). Hematocrit value (Hct), mean corpuscular hemoglobin (MCH), MCH concentration (MCHC; all: P < 0.001), and mean corpuscular volume (MCV; P < 0.01) were higher in canine citrated blood compared to heparin and EDTA. In cats, lymphocytes and monocytes were lower in heparinized blood compared to EDTA (P < 0.05), whereas in horses no significant effect was seen. Regarding storage time and temperature, white and red blood cell counts, hemoglobin, and MCH were stable. Hct, MCV, and MCHC were influenced by erythrocyte swelling. Differential count remained stable for 24 hr (22°C) and nearly 72 hr (4°C) except for monocytes. The overall performance of the Sysmex XT-2000iV was excellent and compared favorably with that of the ADVIA 2120. A special strength was the excellent detection of feline eosinophils.

  12. A Complete System for Polyps Flagging in Virtual Colonoscopy

    DTIC Science & Technology

    2011-04-01

    in this paper) and curvedness as geometric features, applying fuzzy clustering and then using directional gradient concentration to reduce false...with a relative low false positives ( FP ) rate, using heuristic thresholds and texture features. Hong et al., [18], map the 3D surface to a rectangle...polyps submerged in fluid in the database, the results are very promising, achieving 96.4% sensitivity (over 28 polyps) with 1.1 FP per case. However

  13. Field evidence of social influence in the expression of political preferences: the case of secessionists flags in Barcelona.

    PubMed

    Parravano, Antonio; Noguera, José A; Hermida, Paula; Tena-Sánchez, Jordi

    2015-01-01

    Models of social influence have explored the dynamics of social contagion, imitation, and diffusion of different types of traits, opinions, and conducts. However, few behavioral data indicating social influence dynamics have been obtained from direct observation in "natural" social contexts. The present research provides that kind of evidence in the case of the public expression of political preferences in the city of Barcelona, where thousands of citizens supporting the secession of Catalonia from Spain have placed a Catalan flag in their balconies and windows. Here we present two different studies. 1) During July 2013 we registered the number of flags in 26% of the electoral districts in the city of Barcelona. We find that there is a large dispersion in the density of flags in districts with similar density of pro-independence voters. However, by comparing the moving average to the global mean we find that the density of flags tends to be fostered in electoral districts where there is a clear majority of pro-independence vote, while it is inhibited in the opposite cases. We also show that the distribution of flags in the observed districts deviates significantly from that of an equivalent random distribution. 2) During 17 days around Catalonia's 2013 national holiday we observed the position at balcony resolution of the flags displayed in the facades of a sub-sample of 82 blocks. We compare the 'clustering index' of flags on the facades observed each day to thousands of equivalent random distributions. Again we provide evidence that successive hangings of flags are not independent events but that a local influence mechanism is favoring their clustering. We also find that except for the national holiday day the density of flags tends to be fostered in facades located in electoral districts where there is a clear majority of pro-independence vote.

  14. Field Evidence of Social Influence in the Expression of Political Preferences: The Case of Secessionists Flags in Barcelona

    PubMed Central

    Parravano, Antonio; Noguera, José A.; Hermida, Paula; Tena-Sánchez, Jordi

    2015-01-01

    Models of social influence have explored the dynamics of social contagion, imitation, and diffusion of different types of traits, opinions, and conducts. However, few behavioral data indicating social influence dynamics have been obtained from direct observation in “natural” social contexts. The present research provides that kind of evidence in the case of the public expression of political preferences in the city of Barcelona, where thousands of citizens supporting the secession of Catalonia from Spain have placed a Catalan flag in their balconies and windows. Here we present two different studies. 1) During July 2013 we registered the number of flags in 26% of the electoral districts in the city of Barcelona. We find that there is a large dispersion in the density of flags in districts with similar density of pro-independence voters. However, by comparing the moving average to the global mean we find that the density of flags tends to be fostered in electoral districts where there is a clear majority of pro-independence vote, while it is inhibited in the opposite cases. We also show that the distribution of flags in the observed districts deviates significantly from that of an equivalent random distribution. 2) During 17 days around Catalonia’s 2013 national holiday we observed the position at balcony resolution of the flags displayed in the facades of a sub-sample of 82 blocks. We compare the ‘clustering index’ of flags on the facades observed each day to thousands of equivalent random distributions. Again we provide evidence that successive hangings of flags are not independent events but that a local influence mechanism is favoring their clustering. We also find that except for the national holiday day the density of flags tends to be fostered in facades located in electoral districts where there is a clear majority of pro-independence vote. PMID:25961562

  15. Mandating responsible flagging practices as a strategy for reducing the risk of coastal oil spills.

    PubMed

    Miller, Dana D; Hotte, Ngaio; Sumaila, U Rashid

    2014-04-15

    As human civilization is becoming more aware of the negative impact our actions can inflict upon the natural world, the intensification of fossil fuel extraction and industrial development is being met with increasing opposition. In Western Canada, proposals that would increase the volume of petroleum transported by pipelines and by tankers through the coastal waters of British Columbia have engaged the province in debate. To ease public concern on the risk of a coastal oil spill, there are additional commitments that involved parties could make. There is evidence to show that the practice of registering vessels under foreign flags of states that have exhibited failure in compliance with international obligations is more common amongst petroleum tankers that have been involved in large-scale oil spills. To prove that they are committed to reducing the risk of oil spills, businesses need to stop registering their vessels under flags of foreign, non-compliant states.

  16. Kinematics of the typical beach flags start for young adult sprinters.

    PubMed

    Lockie, Robert G; Vickery, William M; Janse de Jonge, Xanne A K

    2012-01-01

    This study profiled beach flags start kinematics for experienced young adult sprinters. Five males and three females (age = 20.8 ± 2.1 years; height = 1.70 ± 0.06 meters [m]; mass = 63.9 ± 6.0 kilograms) completed four sprints using their competition start technique. A high-speed camera, positioned laterally, filmed the start. Data included: start time; hand clearance time; posterior movement from the start line; feet spacing during the start; elbow, hip, knee, trunk lean, and trajectory angles at take-off; and first step length. Timing gates recorded 0-2, 0-5, and 0-20 m time. Spearman's correlations identified variables relating (p ≤ 0.05) to faster start and sprint times. The beach flags start involved sprinters moving 0.18 ± 0.05 m posterior to the start line by flexing both legs underneath the body before turning. Following the turn, the feet were positioned 0.47 ± 0.07 apart. This distance negatively correlated with start (ρ = -0.647), 0-2 (ρ = -0.683), and 0-5 m (ρ = -0.766) time. Beach flags start kinematics at take-off resembled research analyzing track starts and acceleration. The elbow extension angle (137.62 ± 13.45°) of the opposite arm to the drive leg correlated with 0-2 (ρ = -0.762), 0-5 (ρ = -0.810), and 0-20 m (ρ = -0.810) time. Greater arm extension likely assisted with stability during the start, leading to enhanced sprint performance. The drive leg knee extension angle (146.36 ± 2.26°) correlated with start time (ρ = -0.677), indicating a contribution to a faster start completion. A longer first step following the start related to faster 0-5 m time (ρ = -0.690). Sprinters quicker over 0-2 and 0-5 m were also quicker over 20 m (ρ = 0.881-0.952). Beach flags sprinters must ensure their start is completed quickly, such that they can attain a high speed throughout the race. Key pointsThere are specific movement patterns adopted by beach flags sprinters during the start. Sprinters will move posterior to the start time prior to

  17. Configurations of an Articulated Arm and Singularities of Special Multi-Flags

    NASA Astrophysics Data System (ADS)

    Pelletier, Fernand; Slayman, Mayada

    2014-06-01

    P. Mormul has classified the singularities of special multi-flags in terms of "EKR class" encoded by sequences j_1,dots, j_k of integers (see [Singularity Theory Seminar, Warsaw University of Technology, Vol. 8, 2003, 87-100] and [Banach Center Publ., Vol. 65, Polish Acad. Sci., Warsaw, 2004, 157-178]). However, A.L. Castro and R. Montgomery have proposed in I>Israel J. Math. 192 (2012), 381-427] a codification of singularities of multi-flags by RC and RVT codes. The main results of this paper describe a decomposition of each ''EKR'' set of depth 1 in terms of RVT codes as well as characterize such a set in terms of configurations of an articulated arm. Indeed, an analogue description for some ''EKR'' sets of depth 2 is provided. All these results give rise to a complete characterization of all ''EKR'' sets for 1≤ k≤ 4.

  18. FLAG: A multi-dimensional adaptive free-Lagrange code for fully unstructured grids

    SciTech Connect

    Burton, D.E.; Miller, D.S.; Palmer, T.

    1995-07-01

    The authors describe FLAG, a 3D adaptive free-Lagrange method for unstructured grids. The grid elements were 3D polygons, which move with the flow, and are refined or reconnected as necessary to achieve uniform accuracy. The authors stressed that they were able to construct a 3D hydro version of this code in 3 months, using an object-oriented FORTRAN approach.

  19. Astronaut John Young leaps from lunar surface as he salutes U.S. flag

    NASA Technical Reports Server (NTRS)

    1972-01-01

    Astronaut John W. Young, commander of the Apollo 16 lunar landing mission, leaps from the lunar surface as he salutes the U.S. flag during the first Apollo 16 extravehicular activity (EVA-1) on the Moon, as seen in this reproduction taken from a color transmission made by the color TV camera mounted on the Lunar Roving Vehicle. Astronaut Charles M. Duke Jr., lunar module pilot, is standing in the background.

  20. U.S. BICENTENNIAL EXPOSITION AMERICAN FLAG & ARBA SYMBOL PAINTING FINISHED ON THE VAB

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The massive Vehicle Assembly Building provides the focal point for the Bicentennial Exposition on Science and Technology, 3rd Century America. The largest flag ever painted and a large American Revolution Bicentennial Administration symbol adorn the side of the building, overlooking the bicentennial site which features 15 domes housing exhibits. Sixteen federal agencies, 10 U. W. industries and numerous colleges and universities are participating in the Exposition, which runs through September 7.

  1. An analogue of Weyl’s law for quantized irreducible generalized flag manifolds

    SciTech Connect

    Matassa, Marco E-mail: mmatassa@math.uio.no

    2015-09-15

    We prove an analogue of Weyl’s law for quantized irreducible generalized flag manifolds. This is formulated in terms of a zeta function which, similarly to the classical setting, satisfies the following two properties: as a functional on the quantized algebra it is proportional to the Haar state and its first singularity coincides with the classical dimension. The relevant formulas are given for the more general case of compact quantum groups.

  2. World War II soldier salutes the US Flag during a Veteran's Day ceremony to dedicate a memorial

    NASA Technical Reports Server (NTRS)

    2005-01-01

    World War II soldier salutes the US Flag during a Veteran's Day ceremony to dedicate a memorial to 'Smoky, Yorkie Doodle Dandy and Dogs of All Wars' in the Rocky River Reservation, Lakewood, Ohio. November 11, 2005

  3. Implementation and Validation of the BHR Turbulence Model in the FLAG Hydrocode

    SciTech Connect

    Denissen, Nicholas A.; Fung, Jimmy; Reisner, Jon M.; Andrews, Malcolm J.

    2012-08-29

    The BHR-2 turbulence model, developed at Los Alamos National Laboratory for variable density and compressible flows, is implemented in an Arbitrary Lagrangian-Eulerian hydrocode, FLAG. The BHR-2 formulation is discussed, with emphasis on its connection to multi-component flow formulations that underlie FLAG's treatment of multi-species flow. One-dimensional and two-dimensional validation tests are performed and compared to experiment and Eulerian simulations. Turbulence is an often studied and ubiquitous phenomenon in nature, and modeling its effects is essential in many practical applications. Specifically the behavior of turbulence in the presence of strong density gradients and compressibility is of fundamental importance in applications ranging from Inertial Confinement Fusion (ICF) [1], supernovae [2], and atmospheric flows. The BHR closure approach [3] seeks to model the physical processes at work in variable density turbulence including Kelvin-Helmholtz (KH) [4], Rayleigh-Taylor (RT) [5], and Richtmyer-Meshkov (RM) [6], driven turbulence. The effectiveness of the BHR-2 implementation has been demonstrated for variable density mixing in the KH, RT, and RM cases in an Eulerian framework [7]. The primary motivation of the present work is to implement the BHR-2 turbulence model in the Arbitrary Lagrangian-Eulerian (ALE) hydrodynamics code FLAG. The goal is not only to demonstrate results in agreement with previous Eulerian calculations, but also document behavior that arises from the underlying differences in code philosophy.

  4. Composition of cuticular waxes coating flag leaf blades and peduncles of Triticum aestivum cv. Bethlehem.

    PubMed

    Racovita, Radu C; Hen-Avivi, Shelly; Fernandez-Moreno, Josefina-Patricia; Granell, Antonio; Aharoni, Asaph; Jetter, Reinhard

    2016-10-01

    The work herein presents comprehensive analyses of the cuticular wax mixtures covering the flag leaf blade and peduncle of bread wheat (Triticum aestivum) cv. Bethlehem. Overall, Gas Chromatography-Mass Spectrometry and Flame Ionization Detection revealed a wax coverage of flag leaf blades (16 μg/cm(2)) a third that of peduncles (49 μg/cm(2)). Flag leaf blade wax was dominated by 1-alkanols, while peduncle wax contained primarily β-diketone and hydroxy-β-diketones, thus suggesting differential regulation of the acyl reduction and β-diketone biosynthetic pathways in the two analyzed organs. The characteristic chain length distributions of the various wax compound classes are discussed in light of their individual biosynthetic pathways and biosynthetic relationships between classes. Along with previously reported wheat wax compound classes (fatty acids, 1-alkanols, 1-alkanol esters, aldehydes, alkanes, β-diketone, hydroxy-β-diketones, alkylresorcinols and methyl alkylresorcinols), esters of 2-alkanols and three types of aromatic esters (benzyl, phenethyl and p-hydroxyphenethyl) are also reported. In particular, 2-heptanol esters were identified. Detailed analyses of the isomer distributions within 1-alkanol and 2-alkanol ester homologs revealed distinct patterns of esterified acids and alcohols, suggesting several wax ester synthases with very different substrate preferences in both wheat organs. Terpenoids, including two terpenoid esters, were present only in peduncle wax.

  5. Agatha's Flag

    ERIC Educational Resources Information Center

    Williams, Lee Burdette

    2006-01-01

    For years, educators had complained that college students were apathetic, that their turnout at the polls was pitifully low, that they didn't seem to care about national politics. Despite MTV's Rock the Vote campaign in the 2000 election, students didn't show up to vote in any numbers that gave everybody the reason to be hopeful about the nation's…

  6. Clinical study of Mito-FLAG regimen in treatment of relapsed acute myeloid leukemia.

    PubMed

    Luo, Sheng; Cai, Fangfang; Jiang, Lei; Zhang, Shenghui; Shen, Zhijian; Sun, Lan; Gao, Shenmeng

    2013-03-01

    Patients with relapsed acute myeloid leukemia (AML) have unfavorable prognosis and require innovative therapeutic approaches. In this study we used fludarabine combined with a middle dose of cytosine arabinoside (Ara-C), mitoxantrone and granulocyte-colony stimulating factor (G-CSF) as a salvage therapy for patients with relapsed AML in China. Forty-five patients with relapsed AML were treated with the Mito-FLAG regimen consisting of mitoxantrone (7 mg/m(2), day 1, 3 and 5), fludarabine (30 mg/m(2), days 1-5), Ara-C (1 g/m(2), over 3 h every 12 h, days 1-5) and G-CSF [5 μg/kg/day subcutaneously from day 0 until the white blood count (WBC) was >20×10(9)/l]. Patients with a partial response (PR) received another course of the same regimen. Patients with a suitable donor and aged <50 years received allogeneic stem cell transplantation (allo-SCT). Twenty-three patients (51%) and 3 patients (7%) achieved complete remission (CR) and PR, respectively, following one or two courses of Mito-FLAG, and the overall response (OR) rate was 58%. Nine patients (20%) received allo-SCT and 4 patients (9%) succumbed early. Hematological toxicity and infections were the most prominent toxicities of this regimen. Other toxicities included nausea, vomiting, bleeding, hyperbilirubinemia, renal toxicity and arrhythmia. The probability of overall survival (OS) at 4 years was 19% (95% CI, 11-26%) and the probability of 4-year disease-free survival (DFS) was 29% for all 23 patients in CR (95% CI, 18-41%). Our data suggest that Mito-FLAG is a highly effective and well-tolerated salvage regimen for relapsed AML.

  7. American Flag and Mini-DVD Attached to Deck of Phoenix

    NASA Technical Reports Server (NTRS)

    2008-01-01

    This image, released on Memorial Day, May 26, 2008, shows the American flag and a mini-DVD on the Phoenix's deck, which is about 3 ft. above the Martian surface. The mini-DVD from the Planetary Society contains a message to future Martian explorers, science fiction stories and art inspired by the Red Planet, and the names of more than a quarter million earthlings.

    The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development is by Lockheed Martin Space Systems, Denver.

  8. Accessing numeric data via flags and tags: A final report on a real world experiment

    NASA Technical Reports Server (NTRS)

    Kottenstette, J. P.; Freeman, J. E.; Staskin, E. R.; Hargrave, C. W.

    1978-01-01

    An experiment is reported which: extended the concepts of data flagging and tagging to the aerospace scientific and technical literature; generated experience with the assignment of data summaries and data terms by documentation specialists; and obtained real world assessments of data summaries and data terms in information products and services. Inclusion of data summaries and data terms improved users' understanding of referenced documents from a subject perspective as well as from a data perspective; furthermore, a radical shift in document ordering behavior occurred during the experiment toward proportionately more requests for data-summarized items.

  9. U.S. BICENTENNIAL EXPOSITION & PAINTING OF AMERICAN FLAG ON VAB

    NASA Technical Reports Server (NTRS)

    1976-01-01

    Transformation of the U. S. Bicentennial on Science and Technology from an artist's concept to reality is well underway at KSC. At lower right are stages of the Saturn V rocket which will form part of the Exposition. Four of the 15 domes erected to house exhibits by 16 federal agencies and numerous industrial firms are visible in the foreground. At left center, workmen on a scaffold can be seen completing the blue field on the American flag being painted on the Vehicle Assembly Building. The Exposition will be open to the public from May 30 through September 7.

  10. An improved affinity tag based on the FLAG peptide for the detection and purification of recombinant antibody fragments.

    PubMed

    Knappik, A; Plückthun, A

    1994-10-01

    The commercially available monoclonal antibodies M1 and M2 were raised against and bind the FLAG sequence DYKDDDDK with high specificity. Using the calcium-dependent M1 antibody and the FLAG tag attached to the N terminus of various fragments of the antibody McPC603 expressed in Escherichia coli, we found that the M1 antibody binds with almost the same affinity to a much shorter version of this sequence (DYKD). Since most antibody light chains start with an aspartate, the addition of only three additional amino acids to the N terminus is sufficient to detect and quantify the expressed antibody fragments using standard immunological methods. Similarly, the heavy chain can be detected specifically with the sequence DYKD, which requires four additional amino acids since most heavy chains do not start with Asp. The signal sequence of both chains that is necessary for the transport of the chains to the periplasm of E. coli is processed correctly. Furthermore, we investigated the influence of the amino acid at the fifth position of the FLAG sequence on the binding affinity of the M1 antibody and found that a glutamate at this position increased the sensitivity in Western blots sixfold over the original long FLAG sequence containing an aspartate residue at this position. Together, the improved FLAG is a versatile tool for both sensitive detection and one-step purification of recombinant proteins.

  11. Pathological burst fracture in the cervical spine with negative red flags: a case report

    PubMed Central

    Cox, Jocelyn; DeGraauw, Chris; Klein, Erik

    2016-01-01

    Objective: To report on a case of a pathological burst fracture in the cervical spine where typical core red flag tests failed to identify a significant lesion, and to remind chiropractors to be vigilant in the recognition of subtle signs and symptoms of disease processes. Clinical Features: A 61-year-old man presented to a chiropractic clinic with neck pain that began earlier that morning. After a physical exam that was relatively unremarkable, imaging identified a burst fracture in the cervical spine. Intervention & Outcomes: The patient was sent by ambulance to the hospital where he was diagnosed with multiple myeloma. No medical intervention was performed on the fracture. Summary: The patient’s initial physical examination was largely unremarkable, with an absence of clinical red flags. The screening tools were non-diagnostic. Pain with traction and the sudden onset of symptoms prompted further investigation with plain film imaging of the cervical spine. This identified a pathological burst fracture in the C4 vertebrae. PMID:27069270

  12. Photosynthetic Gas Exchange Characteristics of Wheat Flag Leaf Blades and Sheaths during Grain Filling

    PubMed Central

    Araus, José L.; Tapia, Luis

    1987-01-01

    The rate of net CO2 assimilation (A), the stomatal (gs) and residual (gr) conductances to CO2, the intercellular CO2 concentration, the CO2 compensation points at 21% O2 (Γ21) and at 2% O2 (Γ2), and the amounts of dry matter, nitrogen, and carbohydrates were determined, from anthesis through grain filling, in the flag leaf blade and sheath of spring wheat (Triticum aestivum L. cv Kolibri). The nitrogen content and the rate of net CO2 assimilation declined slowly until the onset of senescence in both organs, about 3 weeks after anthesis. During senescence the reduction of A in both organs was not primarily caused by a decrease in gs; the main factor is the decrease in gr. From values of Γ21 and Γ2 it is suggested that the rate of respiration in the light contributing to the CO2 compensation point is higher in sheaths than in blades irrespective of the O2 level considered. The role of sheaths storing and later transporting assimilates to the developing grains seems to be more important for shoot yield than that of sheaths functioning as photosynthetic organs after the onset of senescence occurs. It is suggested that accumulation of carbohydrates in leaves might somehow trigger senescence in the flag leaf blade and sheath simultaneously. PMID:16665757

  13. The differential diagnosis of Huntington's disease-like syndromes: 'red flags' for the clinician.

    PubMed

    Martino, Davide; Stamelou, Maria; Bhatia, Kailash P

    2013-06-01

    A growing number of progressive heredodegenerative conditions mimic the presentation of Huntington's disease (HD). Differentiating among these HD-like syndromes is necessary when a patient with a combination of movement disorders, cognitive decline, behavioural abnormalities and progressive disease course proves negative to the genetic testing for HD causative mutations, that is, IT15 gene trinucleotide-repeat expansion. The differential diagnosis of HD-like syndromes is complex and may lead to unnecessary and costly investigations. We propose here a guide to this differential diagnosis focusing on a limited number of clinical features ('red flags') that can be identified through accurate clinical examination, collection of historical data and a few routine ancillary investigations. These features include the ethnic background of the patient, the involvement of the facio-bucco-lingual and cervical district by the movement disorder, the co-occurrence of cerebellar features and seizures, the presence of peculiar gait patterns and eye movement abnormalities, and an atypical progression of illness. Additional help may derive from the cognitive-behavioural presentation of the patient, as well as by a restricted number of ancillary investigations, mainly MRI and routine blood tests. These red flags should be constantly updated as the phenotypic characterisation and identification of more reliable diagnostic markers for HD-like syndromes progress over the following years.

  14. Precourt presents a flag, flown on Mir to NASA Administrator Goldin

    NASA Technical Reports Server (NTRS)

    1998-01-01

    STS-91 Mission Commander Charles J. Precourt (at microphone) presents an American flag, a special tool, and an optical disc to NASA Administrator Dan Goldin following Discovery's landing at KSC's Shuttle Landing Facility, as Phase I Shuttle/Mir Program Manager Frank Culbertson and the other members of the STS-91 flight crew look on. This landing not only concluded the STS-91 mission, but Phase I of the joint U.S.-Russian International Space Station Program as well. The flag rode aboard Mir from the beginning of the Phase I program and was brought back to Earth by the STS-91 crew. Discovery's main gear touchdown on Runway 15 was at 2:00:00 p.m. EDT on June 12, 1998, on orbit 155 of the mission. The wheels stopped at 2:01:00 p.m. EDT, for a total mission-elapsed time of 9 days, 19 hours, 55 minutes and 1 second. The 91st Shuttle mission was the 44th KSC landing in the history of the Space Shuttle program and the 15th consecutive landing at KSC. Besides Commander Precourt, the STS-91 flight crew also included Pilot Dominic L. Gorie and Mission Specialists Wendy B. Lawrence, Franklin R. Chang-Diaz, Janet Lynn Kavandi and Valery Victorovitch Ryumin of the Russian Space Agency. Astronaut Andrew S. W. Thomas also returned to Earth from Mir as an STS-91 crew member after 141 days in space.

  15. Alterations to calling criteria for Between the Flags (an early warning system)

    PubMed Central

    Davis, Tessa; Nogajski, Bec

    2015-01-01

    Early warning systems aim to detect clinical deterioration of patients at an early stage. Between the Flags was introduced in New South Wales Health for this purpose. When patients are transferred from the emergency department to the ward, there are circumstances when the calling criteria need to be altered to take into account the clinical context. It is recognised that confusion exists among junior medical staff about the process of making alterations to the Between the Flags calling criteria. A quality improvement project was implemented by undertaking a baseline survey of junior medical staff, providing education and training (to junior medical staff on the existing guidelines for making alteration to the calling criteria), and conducting a post-implementation survey. A baseline survey demonstrated that 74% of junior medical staff had received no education on making alterations and only 5% knew how long their alterations would last once the patient was transferred to the ward. This has potentially serious consequences for patient safety following transfer. After implementation of training, we found that 63% of junior medical staff were aware of the guidelines on making alterations and 50% knew how long their alterations would last once the patient was transferred to the ward. We conclude that educating junior medical staff improved knowledge on the guidelines for making alterations to calling criteria. PMID:26734326

  16. Bruhat Order in the Full Symmetric sl(n) Toda Lattice on Partial Flag Space

    NASA Astrophysics Data System (ADS)

    Chernyakov, Yury B.; Sharygin, Georgy I.; Sorin, Alexander S.

    2016-08-01

    In our previous paper [Comm. Math. Phys. 330 (2014), 367-399] we described the asymptotic behaviour of trajectories of the full symmetric sl_n Toda lattice in the case of distinct eigenvalues of the Lax matrix. It turned out that it is completely determined by the Bruhat order on the permutation group. In the present paper we extend this result to the case when some eigenvalues of the Lax matrix coincide. In that case the trajectories are described in terms of the projection to a partial flag space where the induced dynamical system verifies the same properties as before: we show that when tto±∞ the trajectories of the induced dynamical system converge to a finite set of points in the partial flag space indexed by the Schubert cells so that any two points of this set are connected by a trajectory if and only if the corresponding cells are adjacent. This relation can be explained in terms of the Bruhat order on multiset permutations.

  17. FLAGS: A Flexible and Adaptive Association Test for Gene Sets Using Summary Statistics

    PubMed Central

    Huang, Jianfei; Wang, Kai; Wei, Peng; Liu, Xiangtao; Liu, Xiaoming; Tan, Kai; Boerwinkle, Eric; Potash, James B.; Han, Shizhong

    2016-01-01

    Genome-wide association studies (GWAS) have been widely used for identifying common variants associated with complex diseases. Despite remarkable success in uncovering many risk variants and providing novel insights into disease biology, genetic variants identified to date fail to explain the vast majority of the heritability for most complex diseases. One explanation is that there are still a large number of common variants that remain to be discovered, but their effect sizes are generally too small to be detected individually. Accordingly, gene set analysis of GWAS, which examines a group of functionally related genes, has been proposed as a complementary approach to single-marker analysis. Here, we propose a flexible and adaptive test for gene sets (FLAGS), using summary statistics. Extensive simulations showed that this method has an appropriate type I error rate and outperforms existing methods with increased power. As a proof of principle, through real data analyses of Crohn’s disease GWAS data and bipolar disorder GWAS meta-analysis results, we demonstrated the superior performance of FLAGS over several state-of-the-art association tests for gene sets. Our method allows for the more powerful application of gene set analysis to complex diseases, which will have broad use given that GWAS summary results are increasingly publicly available. PMID:26773050

  18. A Potential Role of Flag Leaf Potassium in Conferring Tolerance to Drought-Induced Leaf Senescence in Barley

    PubMed Central

    Hosseini, Seyed A.; Hajirezaei, Mohammad R.; Seiler, Christiane; Sreenivasulu, Nese; von Wirén, Nicolaus

    2016-01-01

    Terminal drought stress decreases crop yields by inducing abscisic acid (ABA) and premature leaf senescence. As potassium (K) is known to interfere with ABA homeostasis we addressed the question whether there is genetic variability regarding the role of K nutrition in ABA homeostasis and drought tolerance. To compare their response to drought stress, two barley lines contrasting in drought-induced leaf senescence were grown in a pot experiment under high and low K supply for the analysis of flag leaves from the same developmental stage. Relative to the drought-sensitive line LPR, the line HPR retained more K in its flag leaves under low K supply and showed delayed flag leaf senescence under terminal drought stress. High K retention was further associated with a higher leaf water status, a higher concentration of starch and other primary carbon metabolites. With regard to ABA homeostasis, HPR accumulated less ABA but higher levels of the ABA degradation products phaseic acid (PA) and dehydro-PA. Under K deficiency this went along with higher transcript levels of ABA8′-HYDROXYLASE, encoding a key enzyme in ABA degradation. The present study provides evidence for a positive impact of the K nutritional status on ABA homeostasis and carbohydrate metabolism under drought stress. We conclude that genotypes with a high K nutritional status in the flag leaf show superior drought tolerance by promoting ABA degradation but attenuating starch degradation which delays flag leaf senescence. Flag leaf K levels may thus represent a useful trait for the selection of drought-tolerant barley cultivars. PMID:26955376

  19. Discovery of C5-C17 poly- and perfluoroalkyl substances in water by in-line SPE-HPLC-Orbitrap with in-source fragmentation flagging.

    PubMed

    Liu, Yanna; Pereira, Alberto Dos Santos; Martin, Jonathan W

    2015-04-21

    The presence of unknown organofluorine compounds in environmental samples has prompted the development of nontargeted analytical methods capable of detecting new perfluoroalkyl and polyfluoroalkyl substances (PFASs). By combining high volume injection with high performance liquid chromatography (HPLC) and ultrahigh resolution Orbitrap mass spectrometry, a sensitive (0.003-0.2 ng F/mL for model mass-labeled PFASs) untargeted workflow was developed for discovery and characterization of novel PFASs in water. In the first step, up to 5 mL of water is injected to in-line solid phase extraction, chromatographed by HPLC, and detected by electrospray ionization with mass spectral acquisition in parallel modes cycling back and forth: (i) full scan with ultrahigh resolving power (RP = 120,000, mass accuracy ≤3 ppm), and (ii) in-source fragmentation flagging scans designed to yield marker fragment ions including [C2F5](-) (m/z 118.992), [C3F7](-) (m/z 168.988), [SO4H](-) (m/z 96.959), and [Cl](-) (m/z 34.9). For flagged PFASs, plausible empirical formulas were generated from accurate masses, isotopic patterns, and fragment ions. In the second step, another injection is made to collect high resolution MS/MS spectra of suspect PFAS ions, allowing further confirmation of empirical formulas while also enabling preliminary structural characterization. The method was validated by applying it to an industrial wastewater, and 36 new PFASs were discovered. Of these, 26 were confidently assigned to 3 new PFAS classes that have not previously been reported in the environment: polyfluorinated sulfates (CnFn+3Hn-2SO4(-); n = 5, 7, 9, 11, 13, and 15), chlorine substituted perfluorocarboxylates (ClCnF2nCO2(-); n = 4-11), and hydro substituted perfluorocarboxylates (HCnF2nCO2(-); n = 5-16). Application of the technique to environmental water samples is now warranted.

  20. DOGO Warn Levels: An Upgrade to Quality Flags for the OCO-2 Data Products

    NASA Astrophysics Data System (ADS)

    Eldering, A.; Mandrake, L.; Doran, G. B., Jr.; O'Dell, C.

    2015-12-01

    All large observational datasets contain varying quality data due to instrument limitations, retrieval software imperfections, and confounding (poorly modeled) effects in the system being observed. Traditionally, we image large percentages of data that are of limited or no scientific use, so called "bad data." The previous solution was for an instrument team to create a binary filter (quality flag) to remove unwanted observations before any analyses are performed. However, quality flags assume fully separable "good"/ "bad" data and produce a fixed percentage of data that may still be too high or low for a particular user's needs. Additionally, atmospheric soundings are confounded by clouds and aerosols that continuously vary in optical depth and size scale without a sharp, simple boundary between "good" and "bad," breaking the data quality concept. OCO2 has for the first time at JPL/NASA developed an alternative to quality flags: the award-winning DOGO (Data Ordering Genetic Optimization) system. DOGO uses machine-learning to derive a coarse ordering of the data from most to least trusted without making arbitrary good/bad decisions. By seeking to reduce metrics like stdev of southern hemisphere XCO2, difference from TCCON, and stdev of global small areas, DOGO searches the space of all possible filters and isolates a handful of predictive metadata features that, through simple formula, can be used to predict an optimal ordering. This ordering seeks to keep the above metrics reduced while gradually admitting more data for analysis. The ordering is crystallized into the Warn Level (WL) product, so named because higher Warn Levels for an individual sounding indicate higher chances that the sounding will not prove useful. Users use WL's by accepting the soundings with lowest values first, then proceeding higher until the data volume need, coverage need, or problem tolerance is reached. DOGO's WL's are the official quality estimation tool provided with OCO-2 data

  1. 46 CFR 42.03-35 - U.S.-flag vessels and Canadian vessels navigating on sheltered waters of Puget Sound and...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false U.S.-flag vessels and Canadian vessels navigating on sheltered waters of Puget Sound and contiguous west coast waters of United States and Canada. 42.03-35... FOREIGN VOYAGES BY SEA Application § 42.03-35 U.S.-flag vessels and Canadian vessels navigating...

  2. Identification of up-regulated genes in flag leaves during rice grain filling and characterization of OsNAC5, a new ABA-dependent transcription factor

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Rice is a poor source of essential micronutrients such as iron and zinc. To help clarify the molecular mechanisms that regulate the mobilization of metals from leaves to developing seeds, we conducted suppression subtractive hybridization analysis in flag leaves of two rice cultivars. Flag leaves ar...

  3. 33 CFR 96.210 - Who does this subpart apply to?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... VESSEL OPERATING REGULATIONS RULES FOR THE SAFE OPERATION OF VESSELS AND SAFETY MANAGEMENT SYSTEMS Company and Vessel Safety Management Systems § 96.210 Who does this subpart apply to? (a) This subpart... company who owns and operates a U.S. flag vessel(s) which does not meet the conditions of paragraph...

  4. 33 CFR 96.210 - Who does this subpart apply to?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... VESSEL OPERATING REGULATIONS RULES FOR THE SAFE OPERATION OF VESSELS AND SAFETY MANAGEMENT SYSTEMS Company and Vessel Safety Management Systems § 96.210 Who does this subpart apply to? (a) This subpart... company who owns and operates a U.S. flag vessel(s) which does not meet the conditions of paragraph...

  5. Preliminary evaluation of an ATR system applied to robotic tank inspection

    SciTech Connect

    Conner, C.; Lassahn, G.; Nash, T.; Briebenow, B.

    1994-12-31

    A brief evaluation of the capabilities of an automatic target recognition system as applied to processing digitized data from robotic inspection of radioactive liquid waste storage tanks has been performed. The intent of this application is to use the target recognition system as a fast data screening tool to flag scenes that might indicate tank defects.

  6. Analysis of xRAGE and flag high explosive burn models with PBX 9404 cylinder tests

    SciTech Connect

    Harrier, Danielle; Andersen, Kyle Richard

    2016-08-05

    High explosives are energetic materials that release their chemical energy in a short interval of time. They are able to generate extreme heat and pressure by a shock driven chemical decomposition reaction, which makes them valuable tools that must be understood. This study investigated the accuracy and performance of two Los Alamos National Laboratory hydrodynamic codes, which are used to determine the behavior of explosives within a variety of systems: xRAGE which utilizes an Eulerian mesh, and FLAG with utilizes a Lagrangian mesh. Various programmed and reactive burn models within both codes were tested using a copper cylinder expansion test. The test was based on a recent experimental setup which contained the plastic bonded explosive PBX 9404. Detonation velocity versus time curves for this explosive were obtained using Photon Doppler Velocimetry (PDV). The modeled results from each of the burn models tested were then compared to one another and to the experimental results. This study validate

  7. Dystonic opisthotonus: a "red flag" for neurodegeneration with brain iron accumulation syndromes?

    PubMed

    Stamelou, Maria; Lai, Scarlett C; Aggarwal, Annu; Schneider, Susanne A; Houlden, Henry; Yeh, Tu-Hsueh; Batla, Amit; Lu, Chin-Song; Bhatt, Mohit; Bhatia, Kailash P

    2013-09-01

    Back arching was reported in one of the very first patients with neurodegeneration with brain iron accumulation syndrome (NBIAs) published in 1936. However, recent reports have mainly focused on the genetic and imaging aspects of these disorders, and the phenotypic characterization of the dystonia has been lost. In evaluating patients with NBIAs in our centers, we have observed that action-induced dystonic opisthotonus is a common and characteristic feature of NBIAs. Here, we present a case series of patients with NBIAs presenting this feature demonstrated by videos. We suggest that dystonic opisthotonus could be a useful "red flag" for clinicians to suspect NBIAs, and we discuss the differential diagnosis of this feature. This would be particularly useful in identifying patients with NBIAs and no iron accumulation as yet on brain imaging (for example, as in phospholipase A2, group IV (cytosolic, calcium-independent) [PLA2G6]-related disorders), and it has management implications.

  8. STS-65 crew onboard portrait in IML-2 spacelab module with mission flag

    NASA Technical Reports Server (NTRS)

    1994-01-01

    In the spacelab science module aboard the Space Shuttle Columbia, Orbiter Vehicle (OV) 102, the seven crewmembers pose for the traditional onboard (inflight) crew portrait. Displayed in the background is a flag with the International Microgravity Laboratory 2 (IML-2) insignia and Columbia inscribed along the edge. In the front row (left to right) are Mission Specialist (MS) Carl E. Walz and MS Donald A. Thomas. Behind them (left to right) are Payload Commander (PLC) Richard J. Hieb, Payload Specialist Chiaki Mukai, Commander Robert D. Cabana, MS Leroy Chiao, and Pilot James D. Halsell, Jr. Mukai represents the National Space Development Agency (NASDA) of Japan. Crewmembers are wearing their mission polo shirts for the portrait. Inside this module, the crew conducted experiments in support of the IML-2 mission.

  9. Environmental Assessment Improvements to Silver Flag Training Area at Tyndall Air Force Base, Florida

    DTIC Science & Technology

    2013-08-02

    shell, and sand. The only paved roads ( asphalt ) are the two  roads that extend from U.S. Highway 98 eastward and northward to the Silver Flag Training...forestry vehicles and   Source: 2010 FDOT Natural Color Imagery 0 1 20.5 Miles LEGEND Dirt Roads Semi-improved Roads Asphalt Roads FIGURE 2-1 Roads Used...stall structure on a 115 ft x 60 ft crushed  concrete base and overlying  asphalt  pad with approach aprons. The structure would be 112 ft long, 50 ft

  10. Flagging and correction of pattern noise in the Kepler focal plane array

    NASA Astrophysics Data System (ADS)

    Kolodziejczak, Jeffery J.; Caldwell, Douglas A.; Van Cleve, Jeffery E.; Clarke, Bruce D.; Jenkins, Jon M.; Cote, Miles T.; Klaus, Todd C.; Argabright, Vic S.

    2010-07-01

    In order for Kepler to achieve its required <20 PPM photometric precision for magnitude 12 and brighter stars, instrument-induced variations in the CCD readout bias pattern (our "2D black image"), which are either fixed or slowly varying in time, must be identified and the corresponding pixels either corrected or removed from further data processing. The two principle sources of these readout bias variations are crosstalk between the 84 science CCDs and the 4 fine guidance sensor (FGS) CCDs and a high frequency amplifier oscillation on <40% of the CCD readout channels. The crosstalk produces a synchronous pattern in the 2D black image with time-variation observed in <10% of individual pixel bias histories. We will describe a method of removing the crosstalk signal using continuously-collected data from masked and over-clocked image regions (our "collateral data"), and occasionally-collected full-frame images and reverse-clocked readout signals. We use this same set to detect regions affected by the oscillating amplifiers. The oscillations manifest as time-varying moiré pattern and rolling bands in the affected channels. Because this effect reduces the performance in only a small fraction of the array at any given time, we have developed an approach for flagging suspect data. The flags will provide the necessary means to resolve any potential ambiguity between instrument-induced variations and real photometric variations in a target time series. We will also evaluate the effectiveness of these techniques using flight data from background and selected target pixels.

  11. KINEMATICS THAT DIFFERENTIATE THE BEACH FLAGS START BETWEEN ELITE AND NON-ELITE SPRINTERS

    PubMed Central

    Vickery, W.M.

    2013-01-01

    This study differentiated the kinematics of the beach flags sprint start between five elite (three males, two females; age = 21.2 ± 2.6 years; height = 1.71 ± 0.04 m; mass = 66.2 ± 5.9 kg) and five non-elite (three males, two females; age = 20.4 ± 1.7 years; height = 1.69 ± 0.08 meters [m]; mass = 61.6 ± 5.7 kilograms) sprinters. A high-speed camera filmed the start. Timing gates recorded the 0-2, 0-5, and 0-20 m intervals. Data included body position during the start and at take-off; start time; first step length; and sprint times. A Mann-Whitney U-test determined significant (p < 0.05) between-group differences; effect sizes (ES) were also calculated. Elite sprinters had a greater take-off trajectory angle (p = 0.01; ES = 2.57), and were faster over the 0-2 (p = 0.02; ES = 1.77), 0-5 (p = 0.05; ES = 1.20), and 0-20 m (p = 0.02; ES = 1.83) intervals. Large effects were found for: greater take-off swing leg hip flexion (ES = 1.13) and trunk lean (ES = 1.37); longer duration start time (ES = 1.33); and longer first step length (ES = 1.23) in elite sprinters. A longer start time assists with force generation, which in conjunction with increased hip flexion, could translate to a longer first step. Increased trunk lean shifts the take-off trajectory angle towards the horizontal. A greater trajectory angle at start take-off, which could be advantageous for force production during sprint performance, is likely necessary for beach flags. PMID:24744496

  12. Flagging and Correction of Pattern Noise in the Kepler Focal Plane Array

    NASA Technical Reports Server (NTRS)

    Kolodziejczak, Jeffery J.; Caldwell, Douglas A.; VanCleve, Jeffrey E.; Clarke, Bruce D.; Jenkins, Jon M.; Cote, Miles T.; Klaus, Todd C.; Argabright, Vic S.

    2010-01-01

    In order for Kepler to achieve its required less than 20 PPM photometric precision for magnitude 12 and brighter stars, instrument-induced variations in the CCD readout bias pattern (our "2D black image"), which are either fixed or slowly varying in time, must be identified and the corresponding pixels either corrected or removed from further data processing. The two principle sources of these readout bias variations are crosstalk between the 84 science CCDs and the 4 fine guidance sensor (FGS) CCDs and a high frequency amplifier oscillation on less than 40% of the CCD readout channels. The crosstalk produces a synchronous pattern in the 2D black image with time-variation observed in less than 10% of individual pixel bias histories. We will describe a method of removing the crosstalk signal using continuously-collected data from masked and over-clocked image regions (our "collateral data"), and occasionally-collected full-frame images and reverse-clocked readout signals. We use this same set to detect regions affected by the oscillating amplifiers. The oscillations manifest as time-varying moir pattern and rolling bands in the affected channels. Because this effect reduces the performance in only a small fraction of the array at any given time, we have developed an approach for flagging suspect data. The flags will provide the necessary means to resolve any potential ambiguity between instrument-induced variations and real photometric variations in a target time series. We will also evaluate the effectiveness of these techniques using flight data from background and selected target pixels.

  13. 49 CFR 214.521 - Flagging equipment for on-track roadway maintenance machines and hi-rail vehicles.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... maintenance machines and hi-rail vehicles. 214.521 Section 214.521 Transportation Other Regulations Relating... WORKPLACE SAFETY On-Track Roadway Maintenance Machines and Hi-Rail Vehicles § 214.521 Flagging equipment for on-track roadway maintenance machines and hi-rail vehicles. Each on-track roadway maintenance...

  14. 49 CFR 214.521 - Flagging equipment for on-track roadway maintenance machines and hi-rail vehicles.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... maintenance machines and hi-rail vehicles. 214.521 Section 214.521 Transportation Other Regulations Relating... WORKPLACE SAFETY On-Track Roadway Maintenance Machines and Hi-Rail Vehicles § 214.521 Flagging equipment for on-track roadway maintenance machines and hi-rail vehicles. Each on-track roadway maintenance...

  15. 49 CFR 214.521 - Flagging equipment for on-track roadway maintenance machines and hi-rail vehicles.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... maintenance machines and hi-rail vehicles. 214.521 Section 214.521 Transportation Other Regulations Relating... WORKPLACE SAFETY On-Track Roadway Maintenance Machines and Hi-Rail Vehicles § 214.521 Flagging equipment for on-track roadway maintenance machines and hi-rail vehicles. Each on-track roadway maintenance...

  16. 49 CFR 214.521 - Flagging equipment for on-track roadway maintenance machines and hi-rail vehicles.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... maintenance machines and hi-rail vehicles. 214.521 Section 214.521 Transportation Other Regulations Relating... WORKPLACE SAFETY On-Track Roadway Maintenance Machines and Hi-Rail Vehicles § 214.521 Flagging equipment for on-track roadway maintenance machines and hi-rail vehicles. Each on-track roadway maintenance...

  17. 49 CFR 214.521 - Flagging equipment for on-track roadway maintenance machines and hi-rail vehicles.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... maintenance machines and hi-rail vehicles. 214.521 Section 214.521 Transportation Other Regulations Relating... WORKPLACE SAFETY On-Track Roadway Maintenance Machines and Hi-Rail Vehicles § 214.521 Flagging equipment for on-track roadway maintenance machines and hi-rail vehicles. Each on-track roadway maintenance...

  18. 48 CFR 47.403-1 - Availability and unavailability of U.S.-flag air carrier service.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... the time in a travel status, including delay at origin and accelerated arrival at destination, by at... gateway airport in the United States would extend time in a travel status by at least 6 hours more than... the time in a travel status by at least 6 hours more than travel by a foreign-flag air...

  19. 41 CFR 301-10.135 - When must I travel using U.S. flag air carrier service?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... use of the U.S. flag air carrier would at least double your en route travel time; or (g) When the... 41 Public Contracts and Property Management 4 2012-07-01 2012-07-01 false When must I travel using... Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES ALLOWABLE TRAVEL...

  20. 48 CFR 47.403-1 - Availability and unavailability of U.S.-flag air carrier service.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... the time in a travel status, including delay at origin and accelerated arrival at destination, by at... gateway airport in the United States would extend time in a travel status by at least 6 hours more than... the time in a travel status by at least 6 hours more than travel by a foreign-flag air...

  1. 46 CFR 42.03-5 - U.S.-flag vessels subject to the requirements of this subchapter.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... requirements of this subchapter. (a) Vessels engaged in foreign voyages or international voyages other than solely Great Lakes voyages. (1) All U.S. flag vessels which engage in foreign voyages or international...: (i) Ships of war; (ii) New vessels of less than 79 feet in length; (iii) Existing vessels of...

  2. Flag leaf photosynthesis and stomatal function of grain sorghum as influenced by changing photosynthetic photon flux densities

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Data on physiological parameters of A, gs, Em, Ci, and IWUE in grain sorghum (Sorghum bicolor L. Moench) is limited. Flag leaves from three plants of two hybrids, grown using added N fertilizer rates of 0.0, 112, and 224 kg ha-1 near Elizabeth, MS were field sampled for these parameters at growth s...

  3. Ground squirrel tail-flag displays alter both predatory strike and ambush site selection behaviours of rattlesnakes.

    PubMed

    Barbour, Matthew A; Clark, Rulon W

    2012-09-22

    Many species approach, inspect and signal towards their predators. These behaviours are often interpreted as predator-deterrent signals--honest signals that indicate to a predator that continued hunting is likely to be futile. However, many of these putative predator-deterrent signals are given when no predator is present, and it remains unclear if and why such signals deter predators. We examined the effects of one such signal, the tail-flag display of California ground squirrels, which is frequently given both during and outside direct encounters with northern Pacific rattlesnakes. We video-recorded and quantified the ambush foraging responses of rattlesnakes to tail-flagging displays from ground squirrels. We found that tail-flagging deterred snakes from striking squirrels, most likely by advertising squirrel vigilance (i.e. readiness to dodge a snake strike). We also found that tail-flagging by adult squirrels increased the likelihood that snakes would leave their ambush site, apparently by elevating the vigilance of nearby squirrels which reduces the profitability of the ambush site. Our results provide some of the first empirical evidence of the mechanisms by which a prey display, although frequently given in the absence of a predator, may still deter predators during encounters.

  4. 14 CFR 121.467 - Flight attendant duty period limitations and rest requirements: Domestic, flag, and supplemental...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the period of elapsed time, using Coordinated Universal Time or local time, that begins at midnight... Universal Time or local time to reflect the total elapsed time. Flight attendant means an individual, other..., FLAG, AND SUPPLEMENTAL OPERATIONS Aircraft Dispatcher Qualifications and Duty Time...

  5. 14 CFR 121.467 - Flight attendant duty period limitations and rest requirements: Domestic, flag, and supplemental...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... the period of elapsed time, using Coordinated Universal Time or local time, that begins at midnight... Universal Time or local time to reflect the total elapsed time. Flight attendant means an individual, other..., FLAG, AND SUPPLEMENTAL OPERATIONS Aircraft Dispatcher Qualifications and Duty Time...

  6. 14 CFR 121.467 - Flight attendant duty period limitations and rest requirements: Domestic, flag, and supplemental...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... the period of elapsed time, using Coordinated Universal Time or local time, that begins at midnight... Universal Time or local time to reflect the total elapsed time. Flight attendant means an individual, other..., FLAG, AND SUPPLEMENTAL OPERATIONS Aircraft Dispatcher Qualifications and Duty Time...

  7. 15 CFR Supplement No. 3 to Part 732 - BIS's “Know Your Customer” Guidance and Red Flags

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ADMINISTRATION REGULATIONS STEPS FOR USING THE EAR Pt. 732, Supp. 3 Supplement No. 3 to Part 732—BIS's “Know Your Customer” Guidance and Red Flags “Know Your Customer” Guidance Various requirements of the EAR are... EAR has occurred or is about to occur. (a) BIS provides the following guidance on how individuals...

  8. 15 CFR Supplement No. 3 to Part 732 - BIS's “Know Your Customer” Guidance and Red Flags

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ADMINISTRATION REGULATIONS STEPS FOR USING THE EAR Pt. 732, Supp. 3 Supplement No. 3 to Part 732—BIS's “Know Your Customer” Guidance and Red Flags “Know Your Customer” Guidance Various requirements of the EAR are... EAR has occurred or is about to occur. (a) BIS provides the following guidance on how individuals...

  9. 15 CFR Supplement No. 3 to Part 732 - BIS's “Know Your Customer” Guidance and Red Flags

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... ADMINISTRATION REGULATIONS STEPS FOR USING THE EAR Pt. 732, Supp. 3 Supplement No. 3 to Part 732—BIS's “Know Your Customer” Guidance and Red Flags “Know Your Customer” Guidance Various requirements of the EAR are... EAR has occurred or is about to occur. (a) BIS provides the following guidance on how individuals...

  10. 15 CFR Supplement No. 3 to Part 732 - BIS's “Know Your Customer” Guidance and Red Flags

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... ADMINISTRATION REGULATIONS STEPS FOR USING THE EAR Pt. 732, Supp. 3 Supplement No. 3 to Part 732—BIS's “Know Your Customer” Guidance and Red Flags “Know Your Customer” Guidance Various requirements of the EAR are... EAR has occurred or is about to occur. (a) BIS provides the following guidance on how individuals...

  11. 14 CFR 121.635 - Dispatch to and from refueling or provisional airports: Domestic and flag operations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Dispatch to and from refueling or... OPERATIONS Dispatching and Flight Release Rules § 121.635 Dispatch to and from refueling or provisional airports: Domestic and flag operations. No person may dispatch an airplane to or from a refueling...

  12. 14 CFR 121.635 - Dispatch to and from refueling or provisional airports: Domestic and flag operations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Dispatch to and from refueling or... OPERATIONS Dispatching and Flight Release Rules § 121.635 Dispatch to and from refueling or provisional airports: Domestic and flag operations. No person may dispatch an airplane to or from a refueling...

  13. 14 CFR 121.635 - Dispatch to and from refueling or provisional airports: Domestic and flag operations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Dispatch to and from refueling or... OPERATIONS Dispatching and Flight Release Rules § 121.635 Dispatch to and from refueling or provisional airports: Domestic and flag operations. No person may dispatch an airplane to or from a refueling...

  14. 14 CFR 121.635 - Dispatch to and from refueling or provisional airports: Domestic and flag operations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Dispatch to and from refueling or... OPERATIONS Dispatching and Flight Release Rules § 121.635 Dispatch to and from refueling or provisional airports: Domestic and flag operations. No person may dispatch an airplane to or from a refueling...

  15. 14 CFR 121.635 - Dispatch to and from refueling or provisional airports: Domestic and flag operations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Dispatch to and from refueling or... OPERATIONS Dispatching and Flight Release Rules § 121.635 Dispatch to and from refueling or provisional airports: Domestic and flag operations. No person may dispatch an airplane to or from a refueling...

  16. Sulfation of the FLAG epitope is affected by co-expression of G protein-coupled receptors in a mammalian cell model

    PubMed Central

    Hunter, Morag Rose; Grimsey, Natasha Lillia; Glass, Michelle

    2016-01-01

    G protein-coupled receptors (GPCRs) are important therapeutic targets and therefore extensively studied. Like most transmembrane proteins, there has been considerable difficulty in developing reliable specific antibodies for them. To overcome this, epitope tags are often used to facilitate antibody recognition in studies on fundamental receptor signalling and trafficking. In our study of cannabinoid CB1/dopamine D2 interactions we sought to generate HEK293 cells expressing FLAG-tagged D2 for use in antibody-based assays of GPCR localisation and trafficking activity, however observed that stable FLAG-hD2 expression was particularly challenging to maintain. In contrast, when expressed in cell lines expressing hCB1 robust and stable FLAG-hD2 expression was observed. We hypothesised that co-expression of CB1 might stabilise surface FLAG-hD2 expression, and therefore investigated this further. Here, we describe the observation that co-expression of either cannabinoid CB1 or CB2 receptors in HEK293 decreases the sulfation of a FLAG epitope appended at the N-terminus of the dopamine D2 receptor. Sulfation alters epitope recognition by some anti-FLAG antibodies, leading to the detection of fewer receptors, even though expression is maintained. This demonstrates that cannabinoid receptor expression modifies posttranslational processing of the FLAG-hD2 receptor, and importantly, has wider implications for the utilisation and interpretation of receptor studies involving epitope tags. PMID:27273047

  17. Use of the RoboFlag synthetic task environment to investigate workload and stress responses in UAV operation.

    PubMed

    Guznov, Svyatoslav; Matthews, Gerald; Funke, Gregory; Dukes, Allen

    2011-09-01

    Use of unmanned aerial vehicles (UAVs) is an increasingly important element of military missions. However, controlling UAVs may impose high stress and workload on the operator. This study evaluated the use of the RoboFlag simulated environment as a means for profiling multiple dimensions of stress and workload response to a task requiring control of multiple vehicles (robots). It tested the effects of two workload manipulations, environmental uncertainty (i.e., UAV's visual view area) and maneuverability, in 64 participants. The findings confirmed that the task produced substantial workload and elevated distress. Dissociations between the stress and performance effects of the manipulations confirmed the utility of a multivariate approach to assessment. Contrary to expectations, distress and some aspects of workload were highest in the low-uncertainty condition, suggesting that overload of information may be an issue for UAV interface designers. The strengths and limitations of RoboFlag as a methodology for investigating stress and workload responses are discussed.

  18. Beyond the French Flag Model: Exploiting Spatial and Gene Regulatory Interactions for Positional Information

    PubMed Central

    Hillenbrand, Patrick; Gerland, Ulrich; Tkačik, Gašper

    2016-01-01

    A crucial step in the early development of multicellular organisms involves the establishment of spatial patterns of gene expression which later direct proliferating cells to take on different cell fates. These patterns enable the cells to infer their global position within a tissue or an organism by reading out local gene expression levels. The patterning system is thus said to encode positional information, a concept that was formalized recently in the framework of information theory. Here we introduce a toy model of patterning in one spatial dimension, which can be seen as an extension of Wolpert’s paradigmatic “French Flag” model, to patterning by several interacting, spatially coupled genes subject to intrinsic and extrinsic noise. Our model, a variant of an Ising spin system, allows us to systematically explore expression patterns that optimally encode positional information. We find that optimal patterning systems use positional cues, as in the French Flag model, together with gene-gene interactions to generate combinatorial codes for position which we call “Counter” patterns. Counter patterns can also be stabilized against noise and variations in system size or morphogen dosage by longer-range spatial interactions of the type invoked in the Turing model. The simple setup proposed here qualitatively captures many of the experimentally observed properties of biological patterning systems and allows them to be studied in a single, theoretically consistent framework. PMID:27676252

  19. SLIPPING MAGNETIC RECONNECTION TRIGGERING A SOLAR ERUPTION OF A TRIANGLE-SHAPED FLAG FLUX ROPE

    SciTech Connect

    Li, Ting; Zhang, Jun E-mail: zjun@nao.cas.cn

    2014-08-10

    We report the first simultaneous activities of the slipping motion of flare loops and a slipping eruption of a flux rope in 131 Å and 94 Å channels on 2014 February 2. The east hook-like flare ribbon propagated with a slipping motion at a speed of about 50 km s{sup –1}, which lasted about 40 minutes and extended by more than 100 Mm, but the west flare ribbon moved in the opposite direction with a speed of 30 km s{sup –1}. At the later phase of flare activity, there was a well developed ''bi-fan'' system of flare loops. The east footpoints of the flux rope showed an apparent slipping motion along the hook of the ribbon. Simultaneously, the fine structures of the flux rope rose up rapidly at a speed of 130 km s{sup –1}, much faster than that of the whole flux rope. We infer that the east footpoints of the flux rope are successively heated by a slipping magnetic reconnection during the flare, which results in the apparent slippage of the flux rope. The slipping motion delineates a ''triangle-shaped flag surface'' of the flux rope, implying that the topology of a flux rope is more complex than anticipated.

  20. CADASIL mimicking multiple sclerosis: The importance of clinical and MRI red flags.

    PubMed

    Joshi, Stuti; Yau, Wayne; Kermode, Allan

    2017-01-01

    Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited small vessel disease, manifesting as recurrent ischaemic events, migraine with aura, behavioural disturbance and cognitive decline. We report two patients with CADASIL masquerading as multiple sclerosis (MS). A 23year old female presented with a visual scotoma and was discovered to have a corresponding retinal cotton wool spot. MRI brain revealed diffuse T2 hyperintensities suggestive of demyelination. A 56year old male presented with transient sequential paraesthesia, initially of the perineum followed by the right leg. He also reported memory and mood impairment with a history of migraine with aura. MRI of the brain showed diffuse bilateral white matter lesions with sparing of the anterior temporal poles. Both patients satisfied the modified McDonald diagnostic criteria and were initially thought to have MS. However, they did not satisfy the caveat of "no better explanation" and on subsequent testing NOTCH 3 mutations were identified in both patients [1]. These cases highlight the importance of careful clinical assessment and neuroimaging findings in identifying clinical and paraclinical 'red-flags' for a diagnosis other than MS.

  1. Patterns of variation among distinct alleles of the Flag silk gene from Nephila clavipes.

    PubMed

    Higgins, Linden E; White, Sheryl; Nuñez-Farfán, Juan; Vargas, Jesus

    2007-02-20

    Spider silk proteins and their genes are very attractive to researchers in a wide range of disciplines because they permit linking many levels of organization. However, hypotheses of silk gene evolution have been built primarily upon single sequences of each gene each species, and little is known about allelic variation within a species. Silk genes are known for their repeat structure with high levels of homogenization of nucleotide and amino acid sequence among repeated units. One common explanation for this homogeneity is gene convergence. To test this model, we sequenced multiple alleles of one intron-exon segment from the Flag gene from four populations of the spider Nephila clavipes and compared the new sequences to a published sequence. Our analysis revealed very high levels of heterozygosity in this gene, with no pattern of population differentiation. There was no evidence of gene convergence within any of these alleles, with high levels of nucleotide and amino acid substitution among the repeating motifs. Our data suggest that minimally, there is relaxed selection on mutations in this gene and that there may actually be positive selection for heterozygosity.

  2. Analysis of Xrage and Flag High Explosive Burn Models with PBX 9404 Cylinder Tests

    NASA Astrophysics Data System (ADS)

    Harrier, Danielle; Fessenden, Julianna; Ramsey, Scott

    2016-11-01

    High explosives are energetic materials that release their chemical energy in a short interval of time. They are able to generate extreme heat and pressure by a shock driven chemical decomposition reaction, which makes them valuable tools that must be understood. This study investigated the accuracy and performance of two Los Alamos National Laboratory hydrodynamic codes, which are used to determine the behavior of explosives within a variety of systems: xRAGE which utilizes an Eulerian mesh, and FLAG with utilizes a Lagrangian mesh. Various programmed and reactive burn models within both codes were tested, using a copper cylinder expansion test. The test was based off of a recent experimental setup which contained the plastic bonded explosive PBX 9404. Detonation velocity versus time curves for this explosive were obtained from the experimental velocity data collected using Photon Doppler Velocimetry (PDV). The modeled results from each of the burn models tested were then compared to one another and to the experimental results using the Jones-Wilkins-Lee (JWL) equation of state parameters that were determined and adjusted from the experimental tests. This study is important to validate the accuracy of our high explosive burn models and the calibrated EOS parameters, which are important for many research topics in physical sciences.

  3. Sorption of sulphamethoxazole by the biochars derived from rice straw and alligator flag.

    PubMed

    Li, Tingqiang; Han, Xuan; Liang, Chengfeng; Shohag, M J I; Yang, Xiaoe

    2015-01-01

    The sorption ability of sulphamethoxazole (SMX) by biochar derived from rice straw (RS) and alligator flag (AF) at 600°C was studied to assess the ability of biochar as adsorbent to remove SMX from aqueous solution. The results indicated that sorption of SMX by biochars was well described using the Langmuir equation (R2>0.94), and the maximum sorption parameter (Q) of RS (3650 mg kg(-1)) was much higher than that of AF (1963 mg kg(-1)). Temperature had no effect on SMX sorption by biochars, while thermodynamics analysis indicated that the sorption of SMX on both biochars was a spontaneous physical process. The d 250 RS (diameter of RS sieved through 250 µm) and d 150 AF (diameter of AF sieved through 150 µm) showed excellent sorption ability for SMX. The sorption amount of RS was larger than that of AF when pH<7, whereas, the sorption amount of AF surpassed RS when pH≥7. The presence of Cu2+ and/or Cd2+ ion at low concentrations (20 mg L(-1)) significantly (P<0.05) increased the sorption of SMX on both RS and AF. Our study confirms that biochar derived from the wetland plants could be used as effective adsorbents to remove SMX from aqueous solution.

  4. STS-55 crewmembers pose with U.S. and German flags in SL-D2 module on OV-102

    NASA Technical Reports Server (NTRS)

    1993-01-01

    STS-55 crewmembers pose with United States and German flags inside the Spacelab Deutsche 2 (SL-D2) science module located in the payload bay (PLB) of Columbia, Orbiter Vehicle (OV) 102. Wearing communications kit assembly headsets (HDSTs) are (left to right) Mission Specialist 1 (MS1) and Payload Commander (PLC) Jerry L. Ross, MS3 Bernard A. Harris, Jr, German Payload Specialist 1 Ulrich Walter, and Payload Specialist 2 Hans Schlegel.

  5. Glutamate dehydrogenase isoforms with N-terminal (His)6- or FLAG-tag retain their kinetic properties and cellular localization.

    PubMed

    Pajęcka, Kamilla; Nielsen, Camilla Wendel; Hauge, Anne; Zaganas, Ioannis; Bak, Lasse K; Schousboe, Arne; Plaitakis, Andreas; Waagepetersen, Helle S

    2014-01-01

    Glutamate dehydrogenase (GDH) is a crucial enzyme on the crossroads of amino acid and energy metabolism and it is operating in all domains of life. According to current knowledge GDH is present only in one functional isoform in most animals, including mice. In addition to this housekeeping enzyme (hGDH1 in humans), humans and apes have acquired a second isoform (hGDH2) with a distinct tissue expression profile. In the current study we have cloned both mouse and human GDH constructs containing FLAG and (His)6 small genetically-encoded tags, respectively. The hGDH1 and hGDH2 constructs containing N-terminal (His)6 tags were successfully expressed in Sf9 cells and the recombinant proteins were isolated to ≥95 % purity in a two-step procedure involving ammonium sulfate precipitation and Ni(2+)-based immobilized metal ion affinity chromatography. To explore whether the presence of the FLAG and (His)6 tags affects the cellular localization and functionality of the GDH isoforms, we studied the subcellular distribution of the expressed enzymes as well as their regulation by adenosine diphosphate monopotassium salt (ADP) and guanosine-5'-triphosphate sodium salt (GTP). Through immunoblot analysis of the mitochondrial and cytosolic fraction of the HEK cells expressing the recombinant proteins we found that neither FLAG nor (His)6 tag disturbs the mitochondrial localization of GDH. The addition of the small tags to the N-terminus of the mature mitochondrial mouse GDH1 or human hGDH1 and hGDH2 did not change the ADP activation or GTP inhibition pattern of the proteins as compared to their untagged counterparts. However, the addition of FLAG tag to the C-terminus of the mouse GDH left the recombinant protein fivefold less sensitive to ADP activation. This finding highlights the necessity of the functional characterization of recombinant proteins containing even the smallest available tags.

  6. 75 FR 13654 - Use of Foreign-Flag Anchor Handling Vessels in the Beaufort Sea or Chukchi Sea Adjacent to Alaska

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-22

    ....-flag vessels are not suitable or reasonably available and if the lessee has entered into a binding contract to obtain and employ an eligible vessel. The lessee has entered into a long term time charter...

  7. Field‐readable alphanumeric flags are valuable markers for shorebirds: use of double‐marking to identify cases of misidentification

    USGS Publications Warehouse

    Roche, Erin A.; Dovichin, Colin M.; Arnold, Todd W.

    2014-01-01

    Implicit assumptions for most mark-recapture studies are that individuals do not lose their markers and all observed markers are correctly recorded. If these assumptions are violated, e.g., due to loss or extreme wear of markers, estimates of population size and vital rates will be biased. Double-marking experiments have been widely used to estimate rates of marker loss and adjust for associated bias, and we extended this approach to estimate rates of recording errors. We double-marked 309 Piping Plovers (Charadrius melodus) with unique combinations of color bands and alphanumeric flags and used multi-state mark recapture models to estimate the frequency with which plovers were misidentified. Observers were twice as likely to read and report an invalid color-band combination (2.4% of the time) as an invalid alphanumeric code (1.0%). Observers failed to read matching band combinations or alphanumeric flag codes 4.5% of the time. Unlike previous band resighting studies, use of two resightable markers allowed us to identify when resighting errors resulted in reports of combinations or codes that were valid, but still incorrect; our results suggest this may be a largely unappreciated problem in mark-resight studies. Field-readable alphanumeric flags offer a promising auxiliary marker for identifying and potentially adjusting for false-positive resighting errors that may otherwise bias demographic estimates.

  8. The rescue and evaluation of FLAG and HIS epitope-tagged Asia 1 type foot-and-mouth disease viruses.

    PubMed

    Yang, Bo; Yang, Fan; Zhang, Yan; Liu, Huanan; Jin, Ye; Cao, Weijun; Zhu, Zixiang; Zheng, Haixue; Yin, Hong

    2016-02-02

    The VP1 G-H loop of the foot-and-mouth disease virus (FMDV) contains the primary antigenic site, as well as an Arg-Gly-Asp (RGD) binding motif for the αv-integrin family of cell surface receptors. We anticipated that introducing a foreign epitope tag sequence downstream of the RGD motif would be tolerated by the viral capsid and would not destroy the antigenic site of FMDV. In this study, we have designed, generated, and characterized two recombinant FMDVs with a FLAG tag or histidine (HIS) inserted in the VP1 G-H loop downstream of the RGD motif +9 position. The tagged viruses were genetically stable and exhibited similar growth properties with their parental virus. What is more, the recombinant viruses rFMDV-FLAG and rFMDV-HIS showed neutralization sensitivity to FMDV type Asia1-specific mAbs, as well as to polyclonal antibodies. Additionally, the r1 values of the recombinant viruses were similar to that of the parental virus, indicating that the insertion of FLAG or HIS tag sequences downstream of the RGD motif +9 position do not eradicate the antigenic site of FMDV and do not affect its antigenicity. These results indicated that the G-H loop of Asia1 FMDV is able to effectively display the foreign epitopes, making this a potential approach for novel FMDV vaccines development.

  9. [Effects of early growth stage shading on rice flag leaf physiological characters and grain growth at grain-filling stage].

    PubMed

    Liu, Qi-hua; Zhou, Xue-biao; Yang, Lian-qun; Li, Tian; Zhang, Jian-jun

    2009-09-01

    In a pot experiment, rice plants were shaded during the period from transplanting to booting, aimed to study the effects of early growth stage shading on the rice growth at grain-filling stage. Comparing with the control, early growth stage shading decreased the tiller number by 26.72%, but increased the flag leaf area and soluble sugar content by 33.86% and 30.23%, respectively. The filled-grain number per panicle, 1000-grain mass, ultimate brown rice mass, and maximum and average grain-filling rates decreased by 8.65%, 4.81%, 9.74%, 20.22%, and 19.13%, and the effective panicle number and grain yield declined by 25.26% and 39.56%, respectively. The peak time of grain-filling rate (Tm) advanced 1.66 days, while the grain-filling time (T99) prolonged 6.80 days. For shading-tolerance variety, its flag leaf Chl a, Chl b, and Chl (a + b) contents at early and mid grain-filling stages, and the protein N and soluble sugar contents and Chl a/b in its flag leaves at grain-filling stage all increased under early growth stage shading, and the ultimate brown rice mass and 1000-grain mass maintained at the similar levels as the control. Consequently, its grain yield reduction rate was lower than that of shading-sensitive variety.

  10. "Flag Excision and Flap" Procedure: a Novel Modification for Off-Midline Closure After Pilonidal Sinus Excision.

    PubMed

    Yucel, Ergun; Tezcan, Levent; Yilmaz, O Cem; Akin, Mehmet Levhi

    2015-12-01

    Pilonidal sinus surgery has evolved with the novel flap techniques, and off-midline closure became a preferred surgical procedure due to shorter recovery time and low recurrence rates. To obtain a better off-midline closure without maceration and a possible wound problem, we modified a novel excision technique. We aimed to present this novel flag modification of rhomboid excision and flap reconstruction experience. From December 2007 to June 2009, 100 patients were treated with flag excision and flap reconstruction under regional anesthesia and followed with a mean of 42 (range 35-55) months. Competent closure results were obtained successfully in all patients without an overlap between incision line and midline. None of the patients had seroma. Two patients (2 %) had partial wound detachment superiorly. None of the patients had recurrence during follow-up. The flag excision and flap reconstruction procedure is an effective and comfortable technique both for the surgeon and the patient with a quick healing period and low complication rates without maceration.

  11. 41 CFR 301-10.137 - What exceptions to the Fly America Act requirements apply when I travel solely outside the United...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false What exceptions to the Fly America Act requirements apply when I travel solely outside the United States, and a U.S. flag air... Air Carriers § 301-10.137 What exceptions to the Fly America Act requirements apply when I...

  12. 41 CFR 301-10.137 - What exceptions to the Fly America Act requirements apply when I travel solely outside the United...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 41 Public Contracts and Property Management 4 2014-07-01 2014-07-01 false What exceptions to the Fly America Act requirements apply when I travel solely outside the United States, and a U.S. flag air... Air Carriers § 301-10.137 What exceptions to the Fly America Act requirements apply when I...

  13. 41 CFR 301-10.137 - What exceptions to the Fly America Act requirements apply when I travel solely outside the United...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 41 Public Contracts and Property Management 4 2011-07-01 2011-07-01 false What exceptions to the Fly America Act requirements apply when I travel solely outside the United States, and a U.S. flag air... Air Carriers § 301-10.137 What exceptions to the Fly America Act requirements apply when I...

  14. A seismic anisotropy study of the Dragon Flag hydrothermal field (49°39'E ) on the Southwest Indian Ridge

    NASA Astrophysics Data System (ADS)

    Zhang, J.; Zhao, M.; Tong, V. C. H.; Qiu, X.

    2015-12-01

    Dragon Flag hydrothermal field located at 49°39'E on the Southwest Indian Ridge contains the active hydrothermal vents firstly discovered on the ultraslow spreading ridge (Tao et al, 2012). Anisotropic study in this area will provide important information tectonic activities. 65634 traveltime residuals from the three-dimensional isotropic inversion (Zhao et al., 2013), were divided into three groups, which correspond to quasi ocean crustal Layer 2 (qL2), quasi ocean crustal Layer 3 (qL3) and quasi uppermost mantle (qUM), respectively. Traveltime residuals at different depths show that there are obvious cosine relationships between traveltime residuals and azimuth of qL2, qL3 and qUM, indicating anisotropy existed in both crust and mantle beneath Dragon Flag hydrothermal field. The best fitted cosine curves indicate that the fast directions (negative traveltime residuals) corresponding to the general trend of ridge axis of N104°E. According to these results, we propose that there may be prevalent cracks penetrating into lower crust or even uppermost mantle. We argue that the hydrothermal convection of Dragon Flag hydrothermal field not only occurs perpendicular to ridge axis, but also occurs parallel to ridge axis. We reveal for the first time anisotropic characteristics of the ultraslow spreading ridge, which has profound scientific significance for the future research on global ocean lithospheric anisotropy. This research was granted by the Natural Science Foundation of China (91028002, 41176053, 91428204). Keywords: ultraslow spreading ridge, Southwest Indian Ridge, Dragon Flag hydrothermal field, P wave traveltime residuals, anisotropy References: Tao C H, Lin J, Guo S, et al. First active hydrothermal vents on an ultraslow-spreading center: Southwest Indian Ridge. Geology, 2012, 40(1): 47~50. Zhao M H, Qiu X L, Li J B, et al. Three-dimensional seismic structure of the Dragon Flag oceanic core complex at the ultraslow spreading Southwest Indian Ridge (49°39

  15. Comparison of flagging, walking, trapping, and collecting from hosts as sampling methods for northern deer ticks, Ixodes dammini, and lone-star ticks, Amblyomma americanum (Acari:Ixodidae).

    PubMed

    Ginsberg, H S; Ewing, C P

    1989-09-01

    Ticks were sampled by flagging, collecting from the investigator's clothing (walking samples), trapping with dry-ice bait, and collecting from mammal hosts on Fire Island, NY, U.S.A. The habitat distribution of adult deer ticks, Ixodes dammini, was the same in simultaneous collections from the investigator's clothing and from muslin flags. Walking and flagging samples can both be biased by differences between investigators, so the same person should do comparative samples whenever possible. Walking samples probably give a more accurate estimate than flagging samples of the human risk of encountering ticks. However, ticks (such as immature I. dammini) that seek hosts in leaf litter and ground-level vegetation are poorly sampled by walking collections. These ticks can be sampled by flagging at ground level. Dry-ice-baited tick-traps caught far more lone-star ticks, Amblyomma americanum, than deer ticks, even in areas where deer ticks predominated in flagging samples. In comparisons of tick mobility in the lab, nymphal A. americanum were more mobile than nymphal I. dammini in 84% of the trials. Therefore, the trapping bias may result from increased trap encounter due to more rapid movement by A. americanum, although greater attraction to carbon dioxide may also play a role. Tick traps are useful for intraspecific between-habitat comparisons. Early in their seasonal activity period, larval I. dammini were better represented in collections from mouse hosts than in flagging samples. Apparently, sampling from favored hosts can detect ticks at low population levels, but often cannot be used to get accurate estimates of pathogen prevalence in questing ticks.

  16. Applied Stratigraphy

    NASA Astrophysics Data System (ADS)

    Lucas, Spencer G.

    Stratigraphy is a cornerstone of the Earth sciences. The study of layered rocks, especially their age determination and correlation, which are integral parts of stratigraphy, are key to fields as diverse as geoarchaeology and tectonics. In the Anglophile history of geology, in the early 1800s, the untutored English surveyor William Smith was the first practical stratigrapher, constructing a geological map of England based on his own applied stratigraphy. Smith has, thus, been seen as the first “industrial stratigrapher,” and practical applications of stratigraphy have since been essential to most of the extractive industries from mining to petroleum. Indeed, gasoline is in your automobile because of a tremendous use of applied stratigraphy in oil exploration, especially during the latter half of the twentieth century. Applied stratigraphy, thus, is a subject of broad interest to Earth scientists.

  17. The Red flag! risk assessment among medical homeopaths in Norway: a qualitative study

    PubMed Central

    2012-01-01

    their clinical practice. A feeling of well-being emerging soon after taking the remedy was the most important criterion for discriminating between Homeopathic Aggravations and Adverse Effects in clinical practice. The Medical Homeopaths used the view of both professions and always looked for red flag situations in the consultation room. They combined knowledge from two treatment systems which may have advantages for the patient. These tentative results deserve further research efforts to improve patient safety among users of homeopathy. For further research we find it important to improve and develop concepts that are unique to homeopathy in order to validate and modernize this medical practice. PMID:22967054

  18. [Effects of tillage pattern on the flag leaf senescence and grain yield of winter wheat under dry farming].

    PubMed

    Huang, Ming; Wu, Jin-Zhi; Li, You-Jun; Yao, Yu-Qing; Zhang, Can-Jun; Cai, Dian-Xiong; Jin, Ke

    2009-06-01

    A field experiment was conducted to study the effects of different tillage patterns, i.e., deep plowing once, no-tillage, subsoiling, and conventional tillage, on the flag leaf senescence and grain yield of winter wheat, as well as the soil moisture and nutrient status under dry farming. No-tillage and subsoiling increased the SOD and POD activities and the chlorophyll and soluble protein contents, decreased the MDA and O2(-.) contents, and postponed the senescence of flag leaf. Under non-tillage and subsoiling, the moisture content in 0-40 cm soil layer at anthesis and grain-filling stages was decreased by 4.13% and 6.23% and by 5.50% and 9.27%, respectively, and the contents of alkali-hydrolysable N, available P, and available K in this soil layer also increased significantly, compared with those under conventional tillage. Deep plowing once decreased the moisture content and increased the nutrients contents in 0-40 cm soil layer, but the decrement and increment were not significant. The post-anthesis biomass, post-anthesis dry matter translocation rate, and grain yield under no-tillage and subsoiling were 4.34% and 4.76%, 15.56% and 13.51%, and 10.22% and 9.26% higher than those under conventional tillage, respectively. It could be concluded that no-tillage and subsoiling provided better soil conditions for the post-anthesis growth of winter wheat, under which, the flag leaf senescence postponed, post-anthesis dry matter accumulation and translocation accelerated, and grain yield increased significantly, being the feasible tillage practices in dry farming winter wheat areas.

  19. Applied oceanography

    SciTech Connect

    Bishop, J.M.

    1984-01-01

    This book combines oceanography principles and applications such as marine pollution, resources, and transportation. It is divided into two main parts treating the basic principles of physical oceanography, and presenting a unique systems framework showing how physical oceanography, marine ecology, economics, and government policy may be combined to define the newly developing field of applied oceanography.

  20. Applied Enzymology.

    ERIC Educational Resources Information Center

    Manoharan, Asha; Dreisbach, Joseph H.

    1988-01-01

    Describes some examples of chemical and industrial applications of enzymes. Includes a background, a discussion of structure and reactivity, enzymes as therapeutic agents, enzyme replacement, enzymes used in diagnosis, industrial applications of enzymes, and immobilizing enzymes. Concludes that applied enzymology is an important factor in…

  1. Immobilization of FLAG-Tagged Recombinant Adeno-Associated Virus 2 onto Tissue Engineering Scaffolds for the Improvement of Transgene Delivery in Cell Transplants.

    PubMed

    Li, Hua; Zhang, Feng-Lan; Shi, Wen-Jie; Bai, Xue-Jia; Jia, Shu-Qin; Zhang, Chen-Guang; Ding, Wei

    2015-01-01

    The technology of virus-based genetic modification in tissue engineering has provided the opportunity to produce more flexible and versatile biomaterials for transplantation. Localizing the transgene expression with increased efficiency is critical for tissue engineering as well as a challenge for virus-based gene delivery. In this study, we tagged the VP2 protein of type 2 adeno-associated virus (AAV) with a 3×FLAG plasmid at the N-terminus and packaged a FLAG-tagged recombinant AAV2 chimeric mutant. The mutant AAVs were immobilized onto the tissue engineering scaffolds with crosslinked anti-FLAG antibodies by N-succinimidyl-3-(2-pyridyldithiol) propionate (SPDP). Cultured cells were seeded to scaffolds to form 3D transplants, and then tested for viral transduction both in vitro and in vivo. The results showed that our FLAG-tagged AAV2 exerted similar transduction efficiency compared with the wild type AAV2 when infected cultured cells. Following immobilization onto the scaffolds of PLGA or gelatin sponge with anti-FLAG antibodies, the viral mediated transgene expression was significantly improved and more localized. Our data demonstrated that the mutation of AAV capsid targeted for antibody-based immobilization could be a practical approach for more efficient and precise transgene delivery. It was also suggested that the immobilization of AAV might have attractive potentials in applications of tissue engineering involving the targeted gene manipulation in 3D tissue cultures.

  2. Applied Nanotoxicology

    PubMed Central

    Hobson, David W.; Roberts, Stephen M.; Shvedova, Anna A.; Warheit, David B.; Hinkley, Georgia K.; Guy, Robin C.

    2016-01-01

    Nanomaterials, including nanoparticles and nanoobjects, are being incorporated into everyday products at an increasing rate. These products include consumer products of interest to toxicologists such as pharmaceuticals, cosmetics, food, food packaging, household products, and so on. The manufacturing of products containing or utilizing nanomaterials in their composition may also present potential toxicologic concerns in the workplace. The molecular complexity and composition of these nanomaterials are ever increasing, and the means and methods being applied to characterize and perform useful toxicologic assessments are rapidly advancing. This article includes presentations by experienced toxicologists in the nanotoxicology community who are focused on the applied aspect of the discipline toward supporting state of the art toxicologic assessments for food products and packaging, pharmaceuticals and medical devices, inhaled nanoparticle and gastrointestinal exposures, and addressing occupational safety and health issues and concerns. This symposium overview article summarizes 5 talks that were presented at the 35th Annual meeting of the American College of Toxicology on the subject of “Applied Nanotechnology.” PMID:26957538

  3. Photosynthetic changes of flag leaves during senescence stage in super high-yield hybrid rice LYPJ grown in field condition.

    PubMed

    Wang, Yuwen; Zhang, Jingjing; Yu, Jing; Jiang, Xiaohan; Sun, Lingang; Wu, Min; Chen, Guoxiang; Lv, Chuangen

    2014-09-01

    Photosynthetic activities and thylakoid membrane protein patterns as well as the ultrastructure of chloroplasts in flag leaves were investigated during the senescence processes in high-yield hybrid rice LYPJ under field condition. The earlier decrease of PS I activity than PS II in LYPJ was primarily due to the significant degradation of PS I chlorophyll-protein complex. The degradation rate for each chlorophyll-protein complex was different and the order for the stability of thylakoid membrane complexes during flag leaf senescence in rice LYPJ was: LHCII > OEC > PSII core antenna > PSII core > PSI core > LHCI, which was partly supported by the BN-PAGE gel combined with immunoblot analysis. A decrease in the chlorophyll a/b ratio at the senescence stage was observed to coincide with stability of the LHCII subunits. Ultrastructural investigations revealed that the chloroplasts have large loosen stacking grana without interconnecting stroma thylakoids during the senescence processes. It was hypothesized that the stability of grana thylakoids harboring the major LHCII under high radiation condition in summer might played a key role in the dissipation of excess light energy. This alternative strategy would protect photosynthetic apparatus from photodamage and might be causally related to the high yield of this rice cultivar.

  4. 41 CFR 301-10.136 - What exceptions to the Fly America Act requirements apply when I travel between the United States...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 41 Public Contracts and Property Management 4 2014-07-01 2014-07-01 false What exceptions to the Fly America Act requirements apply when I travel between the United States and another country? 301-10... Transportation Use of United States Flag Air Carriers § 301-10.136 What exceptions to the Fly America...

  5. 41 CFR 301-10.136 - What exceptions to the Fly America Act requirements apply when I travel between the United States...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false What exceptions to the Fly America Act requirements apply when I travel between the United States and another country? 301-10... Transportation Use of United States Flag Air Carriers § 301-10.136 What exceptions to the Fly America...

  6. 41 CFR 301-10.136 - What exceptions to the Fly America Act requirements apply when I travel between the United States...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 41 Public Contracts and Property Management 4 2011-07-01 2011-07-01 false What exceptions to the Fly America Act requirements apply when I travel between the United States and another country? 301-10... Transportation Use of United States Flag Air Carriers § 301-10.136 What exceptions to the Fly America...

  7. 41 CFR 301-10.136 - What exceptions to the Fly America Act requirements apply when I travel between the United States...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... destination, you must use the U.S. flag air carrier service unless such use would extend your travel time... the U.S. by 2 or more; or (2) Extend your travel time by at least 6 hours or more; or (3) Require a... Fly America Act requirements apply when I travel between the United States and another country?...

  8. 41 CFR 301-10.137 - What exceptions to the Fly America Act requirements apply when I travel solely outside the United...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... or more; or (b) Extend your travel time by 6 hours or more; or (c) Require a connecting time of 4... Fly America Act requirements apply when I travel solely outside the United States, and a U.S. flag air... Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL...

  9. 41 CFR 301-10.137 - What exceptions to the Fly America Act requirements apply when I travel solely outside the United...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... or more; or (b) Extend your travel time by 6 hours or more; or (c) Require a connecting time of 4... Fly America Act requirements apply when I travel solely outside the United States, and a U.S. flag air... Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL...

  10. 41 CFR 301-10.136 - What exceptions to the Fly America Act requirements apply when I travel between the United States...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... destination, you must use the U.S. flag air carrier service unless such use would extend your travel time... the U.S. by 2 or more; or (2) Extend your travel time by at least 6 hours or more; or (3) Require a... Fly America Act requirements apply when I travel between the United States and another country?...

  11. Applied geodesy

    SciTech Connect

    Turner, S.

    1987-01-01

    This volume is based on the proceedings of the CERN Accelerator School's course on Applied Geodesy for Particle Accelerators held in April 1986. The purpose was to record and disseminate the knowledge gained in recent years on the geodesy of accelerators and other large systems. The latest methods for positioning equipment to sub-millimetric accuracy in deep underground tunnels several tens of kilometers long are described, as well as such sophisticated techniques as the Navstar Global Positioning System and the Terrameter. Automation of better known instruments such as the gyroscope and Distinvar is also treated along with the highly evolved treatment of components in a modern accelerator. Use of the methods described can be of great benefit in many areas of research and industrial geodesy such as surveying, nautical and aeronautical engineering, astronomical radio-interferometry, metrology of large components, deformation studies, etc.

  12. Cerebral vasculitis in adults: what are the steps in order to establish the diagnosis? Red flags and pitfalls

    PubMed Central

    Berlit, P; Kraemer, M

    2014-01-01

    Cerebral vasculitis is a rare cause of juvenile stroke. It may occur as primary angiitis of the central nervous system (PACNS) or as CNS manifestation in the setting of systemic vasculitis. Clinical hints for vasculitis are headache, stroke, seizures, encephalopathy and signs of a systemic inflammatory disorder. Diagnostic work-up includes anamnesis, whole body examination, laboratory and cerebral spinal fluid (CSF) studies, magnetic resonance imaging (MRI), angiography and brain biopsy. Due to the rarity of the disease, exclusion of more frequent differential diagnoses is a key element of diagnostic work-up. This review summarizes the steps that lead to the diagnosis of cerebral vasculitis and describes the red flags and pitfalls. Despite considering the dilemma of angiography-negative vasculitis and false-negative brain biopsy in some cases, it is important to protect patients from ‘blind’ immunosuppressive therapy in unrecognized non-inflammatory differential diagnosis. PMID:24117125

  13. Is animal cruelty a "red flag" for family violence? Investigating co-occurring violence toward children, partners, and pets.

    PubMed

    Degue, Sarah; Dilillo, David

    2009-06-01

    Cross-reporting legislation, which permits child and animal welfare investigators to refer families with substantiated child maltreatment or animal cruelty for investigation by parallel agencies, has recently been adopted in several U.S. jurisdictions. The current study sheds light on the underlying assumption of these policies-that animal cruelty and family violence commonly co-occur. Exposure to family violence and animal cruelty is retrospectively assessed using a sample of 860 college students. Results suggest that animal abuse may be a red flag indicative of family violence in the home. Specifically, about 60% of participants who have witnessed or perpetrated animal cruelty as a child also report experiences with child maltreatment or domestic violence. Differential patterns of association were revealed between childhood victimization experiences and the type of animal cruelty exposure reported. This study extends current knowledge of the links between animal- and human-directed violence and provides initial support for the premise of cross-reporting legislation.

  14. Physiotherapy co-management of rheumatoid arthritis: identification of red flags, significance to clinical practice and management pathways.

    PubMed

    Briggs, Andrew M; Fary, Robyn E; Slater, Helen; Ranelli, Sonia; Chan, Madelynn

    2013-12-01

    Rheumatoid arthritis (RA) is a chronic, systemic, autoimmune disease. Physiotherapy interventions for people with RA are predominantly targeted at ameliorating disability resulting from articular and peri-articular manifestations of the disease and providing advice and education to improve functional capacity and quality of life. To ensure safe and effective care, it is critical that physiotherapists are able to identify potentially serious articular and peri-articular manifestations of RA, such as instability of the cervical spine. Additionally, as primary contact professionals, it is essential that physiotherapists are aware of the potentially serious extra-articular manifestations of RA. This paper provides an overview of the practice-relevant manifestations associated with RA that might warrant further investigation by a medical practitioner (red flags), their relevance to physiotherapy practice, and recommended management pathways.

  15. [Flag leaf photosynthetic characteristics, change in chlorophyll fluorescence parameters, and their relationships with yield of winter wheat sowed in spring].

    PubMed

    Xu, Lan; Gao, Zhi-qang; An, Wei; Li, Yan-liang; Jiao, Xiong-fei; Wang, Chuang-yun

    2016-01-01

    With five good winter wheat cultivars selected from the middle and lower reaches of Yangtze River and Southwest China as test materials, a field experiment in Xinding basin area of Shanxi Province was conducted to study the photosynthetic characteristics, chlorophyll content, and chlorophyll fluorescence parameters of flag leaf at different sowing dates, as well as the correlations between these indices and yield for two years (2013-2014). The results showed that the difference in most fluorescence parameters except chlorophyll content among cultivars was significant. The correlations between these fluorescence parameters and yield were significant. The variation coefficient of chlorophyll (Chl) content was low (0.12-0.17), and that of performance index based on absorption (PIabs) was high (0.32-0.39), with the partial correlation coefficients of them with grain yield from 2013 to 2014 ranged in 0.70-0.81. Under the early sowing condition, the grain yield positively correlated with PIabs at flowering and filling stages and chlorophyll content at grain filling stage, but negatively correlated with the relative variable fluorescence at I point (Vi) at grain filling stage. About 81.1%-82.8% of grain yield were determined by the variations of PIabs, Chl, and Vi. Wheat cultivars had various performances in the treatments with different sowing dates and a consistent trend was observed in the two experimental years. Among these 5 cultivars, Yangmai 13 was suitable for early sowing, with the flag leaf photosynthetic rate (Pn), Chl, most fluorescence parame-ters, and grain yield showed obviously high levels. In conclusion, under early sowing condition chlorophyll content at grain filling stages, PIabs at flowering and filling stages, and Pn were important indices for selecting wheat cultivars with high photosynthetic efficiency.

  16. Evaluating the Advisory Flags and Machine Scoring Difficulty in the "e-rater"® Automated Scoring Engine. Research Report. ETS RR-16-30

    ERIC Educational Resources Information Center

    Zhang, Mo; Chen, Jing; Ruan, Chunyi

    2016-01-01

    Successful detection of unusual responses is critical for using machine scoring in the assessment context. This study evaluated the utility of approaches to detecting unusual responses in automated essay scoring. Two research questions were pursued. One question concerned the performance of various prescreening advisory flags, and the other…

  17. Photochemical properties in flag leaves of a super-high-yielding hybrid rice and a traditional hybrid rice (Oryza sativa L.) probed by chlorophyll a fluorescence transient.

    PubMed

    Zhang, Meiping; Shan, YongJie; Kochian, Leon; Strasser, Reto J; Chen, GuoXiang

    2015-12-01

    Chlorophyll a fluorescence of flag leaves in a super-high-yielding hybrid rice (Oryza sativa L.) LYPJ, and a traditional hybrid rice SY63 cultivar with lower grain yield, which were grown in the field, were investigated from emergence through senescence of flag leaves. As the flag leaf matured, there was an increasing trend in photosynthetic parameters such as quantum efficiency of primary photochemistry ([Formula: see text] Po) and efficiency of electron transport from PS II to PS I (Ψ Eo). The overall photosynthetic performance index (PIABS) was significantly higher in the high-yielding LYPJ compared to SY63 during the entire reproductive stage of the plant, the same to MDA content. However, [Formula: see text] Po(=F V/F M), an indicator of the primary photochemistry of the flag leaf, did not display significant changes with leaf age and was not significantly different between the two cultivars, suggesting that PIABS is a more sensitive parameter than [Formula: see text] Po (=F V/F M) during leaf age for distinguishing between cultivars differing in yield.

  18. FLAG tagging by CuAAC and nanogram-scale purification of the target protein for a bioactive metabolite involved in circadian rhythmic leaf movement in Leguminosae.

    PubMed

    Manabe, Yoshiyuki; Mukai, Makoto; Ito, Satoko; Kato, Nobuki; Ueda, Minoru

    2010-01-21

    We report a stepwise FLAG-tagging strategy for the purification of target proteins for bioactive metabolites. This method realizes the microscale purification and identification of target protein from as few as 1 x 10(5) differentiated cells. Using this method, we isolated and identified MetE as a cytosolic target protein of potassium isolespedezate, a metabolite controlling plant nyctinasty.

  19. Identification of predominant genes involved in regulation and execution of senescence-associated nitrogen remobilization in flag leaves of field grown barley.

    PubMed

    Hollmann, Julien; Gregersen, Per L; Krupinska, Karin

    2014-07-01

    The transcriptomes of senescing flag leaves collected from barley field plots with standard or high nitrogen supply were compared to identify genes specifically associated with nitrogen remobilization during leaf senescence under agronomically relevant conditions. In flag leaves collected in field plots with high nitrogen supply, the decline in chlorophyll content was delayed. By comparing changes in gene expression for the two nitrogen levels, it was possible to discriminate genes related to nitrogen remobilization during senescence and genes involved in other processes associated with the late development of leaves under field conditions. Predominant genes that were more strongly upregulated during senescence of flag leaves from plants with standard nitrogen supply included genes encoding the transcription factor HvNAC026, serine type protease SCPL51, and the autophagy factors APG7 and ATG18F. Elevated expression of these genes in senescing leaves from plants with standard nitrogen supply indicates important roles of the corresponding proteins in nitrogen remobilization. In comparison, the genes upregulated in both flag leaf samples might have roles in general senescence processes associated with late leaf development. Among these genes were the transcription factor genes HvNAC001, HvNAC005, HvNAC013, HvWRKY12 and MYB, genes encoding the papain-like cysteine peptidases HvPAP14 and HvPAP20, as well as a subtilase gene.

  20. A Review of ETS Differential Item Functioning Assessment Procedures: Flagging Rules, Minimum Sample Size Requirements, and Criterion Refinement. Research Report. ETS RR-12-08

    ERIC Educational Resources Information Center

    Zwick, Rebecca

    2012-01-01

    Differential item functioning (DIF) analysis is a key component in the evaluation of the fairness and validity of educational tests. The goal of this project was to review the status of ETS DIF analysis procedures, focusing on three aspects: (a) the nature and stringency of the statistical rules used to flag items, (b) the minimum sample size…

  1. 46 CFR 42.03-35 - U.S.-flag vessels and Canadian vessels navigating on sheltered waters of Puget Sound and...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... FOREIGN VOYAGES BY SEA Application § 42.03-35 U.S.-flag vessels and Canadian vessels navigating on... outside their boundary on any voyage cannot claim the benefits of this Treaty and shall be in compliance... the 1960 International Convention on Safety of Life at Sea, those passenger vessels navigating on...

  2. Development of a Yellow Flag Assessment Tool for Orthopaedic Physical Therapists: Results From the Optimal Screening for Prediction of Referral and Outcome (OSPRO) Cohort.

    PubMed

    Lentz, Trevor A; Beneciuk, Jason M; Bialosky, Joel E; Zeppieri, Giorgio; Dai, Yunfeng; Wu, Samuel S; George, Steven Z

    2016-05-01

    Study Design Clinical measurement, cross-sectional. Background Pain-associated psychological distress adversely influences outcomes for patients with musculoskeletal pain. However, assessment of pain-associated psychological distress (ie, yellow flags) is not routinely performed in orthopaedic physical therapy practice. A standardized yellow flag assessment tool will better inform treatment decision making related to psychologically informed practice. Objectives To describe the development of a concise, multidimensional yellow flag assessment tool for application in orthopaedic physical therapy clinical practice. Methods A 136-item yellow flag item bank was developed from validated psychological questionnaires across domains related to pain vulnerability (negative mood, fear avoidance) and resilience (positive affect/coping). Patients seeking physical therapy with neck, back, knee, or shoulder pain completed the item bank. Iterative statistical analyses determined minimal item sets meeting thresholds for identifying elevated vulnerability or low resilience (ie, upper or lower quartile, as indicated). Further item reduction yielded a concise yellow flag assessment tool to assess 11 psychological constructs measuring pain-associated psychological distress. Correlations between the assessment tool and individual psychological questionnaires were measured and compared between anatomical regions. Concurrent validity was assessed by determining variance explained in pain and disability scores by the assessment tool. Results Subjects with elevated vulnerability and decreased resilience were identified with a high degree of accuracy (minimum of 85%) using a 17-item tool. Correlations were moderate to high between the 17-item tool and individual psychological questionnaires, with no significant differences in correlations between different anatomical regions. Shorter 10- and 7-item versions of the assessment tool allow clinicians the flexibility to assess for yellow flags

  3. [PS II photochemical efficiency in flag leaf of wheat varieties and its adaptation to strong sun- light intensity on farmland of Xiangride in Qinghai Province, Northwest China].

    PubMed

    Shi, Sheng-Bo; Chen, Wen-Jie; Shi, Rui; Li, Miao; Zhang, Huai-Gang; Sun, Ya-Nan

    2014-09-01

    Taking four wheat varieties developed by Northwest Institute of Plateau Biology, Chinese Academy of Sciences, as test materials, with the measurement of content of photosynthetic pigments, leaf area, fresh and dry mass of flag leaf, the PS II photochemistry efficiency of abaxial and adaxial surface of flag leaf and its adaptation to strong solar radiation during the period of heading stage in Xiangride region were investigated with the pulse-modulated in-vivo chlorophyll fluorescence technique. The results indicated that flag leaf angle mainly grew in horizontal state in Gaoyuan 314, Gaoyuan 363 and Gaoyuan 584, and mainly in vertical state in Gaoyuan 913 because of its smaller leaf area and larger width. Photosynthetic pigments were different among the 4 varieties, and positively correlated with intrinsic PS II photochemistry efficiencies (Fv/Fm). In clear days, especially at noon, the photosynthetic photoinhibition was more serious in abaxial surface of flag leaf due to directly facing the solar radiation, but it could recover after reduction of sunlight intensity in the afternoon, which meant that no inactive damage happened in PS II reaction centers. There were significant differences of PS II actual and maximum photochemical efficiencies at the actinic light intensity (ΦPS II and Fv'/Fm') between abaxial and adaxial surface, and their relative variation trends were on the contrary. The photochemical and non-photochemical quenching coefficients (qP and NPQ) had a similar tendency in both abaxial and adaxial surfaces. Although ΦPS II and qP were lower in adaxial surface of flag leaf, the Fv'/Fm' was significantly higher, which indicated that the potential PS II capture efficiency of excited energy was higher. The results demonstrated that process of photochemical and non-photochemical quenching could effectively dissipate excited energy caused by strong solar radiation, and there were higher adaptation capacities in wheat varieties natively cultivated in

  4. A prognostic model for survival after salvage treatment with FLAG-Ida +/- gemtuzumab-ozogamicine in adult patients with refractory/relapsed acute myeloid leukaemia.

    PubMed

    Bergua, Juan M; Montesinos, Pau; Martinez-Cuadrón, David; Fernández-Abellán, Pascual; Serrano, Josefina; Sayas, María J; Prieto-Fernandez, Julio; García, Raimundo; García-Huerta, Ana J; Barrios, Manuel; Benavente, Celina; Pérez-Encinas, Manuel; Simiele, Adriana; Rodríguez-Macias, Gabriela; Herrera-Puente, Pilar; Rodríguez-Veiga, Rebeca; Martínez-Sánchez, María P; Amador-Barciela, María L; Riaza-Grau, Rosalía; Sanz, Miguel A

    2016-09-01

    The combination of fludarabine, cytarabine, idarubicin, and granulocyte colony-stimulating factor (FLAG-Ida) is widely used in relapsed/refractory acute myeloid leukaemia (AML). We retrospectively analysed the results of 259 adult AML patients treated as first salvage with FLAG-Ida or FLAG-Ida plus Gentuzumab-Ozogamicin (FLAGO-Ida) of the Programa Español de Tratamientos en Hematología (PETHEMA) database, developing a prognostic score system of survival in this setting (SALFLAGE score). Overall, 221 patients received FLAG-Ida and 38 FLAGO-Ida; 92 were older than 60 years. The complete remission (CR)/CR with incomplete blood count recovery (CRi) rate was 51%, with 9% of induction deaths. Three covariates were associated with lower CR/CRi: high-risk cytogenetics and t(8;21) at diagnosis, no previous allogeneic stem cell transplantation (allo-SCT) and relapse-free interval <1 year. Allo-SCT was performed in second CR in 60 patients (23%). The median overall survival (OS) of the entire cohort was 0·7 years, with 22% OS at 5-years. Four independent variables were used to construct the score: cytogenetics, FLT3-internal tandem duplication, length of relapse-free interval and previous allo-SCT. Using this stratification system, three groups were defined: favourable (26% of patients), intermediate (29%) and poor-risk (45%), with an expected 5-year OS of 52%, 26% and 7%, respectively. The SALFLAGE score discriminated a subset of patients with an acceptable long-term outcome using FLAG-Ida/FLAGO-Ida regimen. The results of this retrospective analysis should be validated in independent external cohorts.

  5. 48 CFR 752.247-70 - Preference for privately owned U.S.-flag commercial vessels.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... under P.L. 480 financed by the U.S. Department of Agriculture, that may be transported in ocean vessels (computed separately for dry bulk carriers, dry cargo liners, and tankers) shall be transported in privately... regulations of the Maritime Administration, USAID applies Cargo Preference requirements on the basis...

  6. Advance of the Black Flags: Symbolism, Social Identity, and Psychological Operations in Violent Conflict

    DTIC Science & Technology

    2015-12-01

    groups, and judgment is carried out to avenge religious unfaithfulness or violence directed toward the Islamic State...audiences’ attitudes and behaviors.370 The use of PSYOP to disrupt decision making and influence ideological conditions is considered a...and film. The roles of symbolism, rituals, and music in human behavior were further researched. This research was then applied to the Islamic

  7. Performance Appraisal Applied to Leadership

    ERIC Educational Resources Information Center

    Jefferson, Anne L.

    2010-01-01

    Performance appraisal is a measurement process of how well an individual is doing her or his job. In most organisations, this appraisal is an annual event. Generally, it is done to encourage job performance, to flag areas that need attention, to inform both parties as to expectations. Much of the literature speaks to this process in terms of the…

  8. Psychiatric comorbidity, red flag behaviors, and associated outcomes among office-based buprenorphine patients following Hurricane Sandy.

    PubMed

    Williams, Arthur R; Tofighi, Babak; Rotrosen, John; Lee, Joshua D; Grossman, Ellie

    2014-04-01

    supply disruption, (3) a pre-storm history of red flag behaviors (in particular, repeat opioid-positive urines), and (4) new-onset post-storm psychiatric symptoms. Our findings highlight the relative resilience of buprenorphine as an office-based treatment modality for patients encountering a disaster with associated unanticipated service disruption. In responding to future disasters, triaging patient contact and priority based on a history of red-flag behaviors, rather than a history of psychiatric comorbidity, will likely optimize resource allocation, especially among recently enrolled patients. Additionally, patients endorsing new-onset psychiatric manifestations following disasters may be an especially high-risk group for poor outcomes, warranting further study.

  9. Waving the Red Flag: FTC Regulation of Deceptive Weight-Loss Advertising 1951-2009.

    PubMed

    Lellis, Julie C

    2016-01-01

    This article documents the historical role of the Federal Trade Commission (FTC) in regulating deceptive weight-loss advertising, which the commission began to prioritize in the 1990s after a dramatic rise in complaints. It also includes the results of a content analysis of more than 150 FTC complaints filed between 1951 and 2009, which were used to analyze trends in advertising content, liability for deceptive practices, and outcomes. Regulatory efforts may not have curbed the use of bogus weight-loss claims, which have only increased over time. The FTC has made attempts to apply broad liability, but advertisers and corporate leaders continue to be named most frequently over other respondents, including advertising agencies, media outlets, and product endorsers. Although the number of complaints that result in financial penalties is increasing, the FTC lacks systematic and specific policies to adequately deter advertisers and address what continues to be a growing problem.

  10. Is it possible to revive the flagging interest in thermography for neurology?

    NASA Astrophysics Data System (ADS)

    Stulin, Igor D.

    1993-11-01

    The paper describes the results of twenty-years of experience in applying thermography (thermal imaging) in routine and urgent neurology, based on the study of more than ten thousand patients. Stress is laid on the fact that thermography is of great significance for diagnosing dextrocerebral hemorrhagic insult with a manifestation of pronounced hemihypothermia in the paralyzed limbs, identifying paraorbital hyperthermia on the side of rhinogenous cerebral abscess, for instrumental registration of transitory heat-up of the nasolabial region in the case of patients suffering from hypertensive nasal bleeding. Much attention is given to diagnosis of intra- and extracerebral phlebopathy in urgent neurology -- early diagnosis of iatrogenic catheterization phlebitis, interference with the venous return in the paralyzed lower limb. The novelty here is the employment of telethermography for complex diagnosis of cerebral death.

  11. Ontogenetic Change of Signal Brightness in the Foot-Flagging Frog Species Staurois parvus and Staurois guttatus

    PubMed Central

    Stangel, Judith; Preininger, Doris; Sztatecsny, Marc; Hödl, Walter

    2015-01-01

    Adult individuals of several anuran species exhibit conspicuous visual displays during intraspecific communication. While signal properties in adults have been subject to an increasing number of studies, little is known about the variation of visual signals in juveniles and during ontogenetic changes. Foot-flagging signals of the Bornean frogs Staurois guttatus and S. parvus were observed in juveniles a few days after metamorphosis. We investigated color parameters of foot webbings and body coloration of individuals bred at the Vienna Zoo, and their relation to age and body size using spectrophotometry. Our results indicate that the brightness of foot webbings of S. guttatus and S. parvus increased with increasing age. Additionally, we compared the results with measurements of adult individuals from a population in Brunei and discuss possible differences related to diet and age as well as the habitat use of juveniles and adults. We suggest that the ontogenetic increase in foot-webbing brightness enhances visual conspicuousness and the signal-to-noise ratio of the visual signal with sexual maturity and potentially functions as cue to the age of the signaler. PMID:25983337

  12. Trigonometric weight functions as K-theoretic stable envelope maps for the cotangent bundle of a flag variety

    NASA Astrophysics Data System (ADS)

    Rimányi, R.; Tarasov, V.; Varchenko, A.

    2015-08-01

    We consider the cotangent bundle T∗Fλ of a GLn partial flag variety, λ =(λ1 , … ,λN) , | λ | =∑iλi = n, and the torus T =(C×) n + 1 equivariant K-theory algebra KT(T∗Fλ) . We introduce K-theoretic stable envelope maps Stabσ :⨁ | λ | = nKT((T∗Fλ) T) →⨁ | λ | = nKT(T∗Fλ) , where σ ∈Sn. Using these maps we define a quantum loop algebra action on ⨁ | λ | = nKT(T∗Fλ) . We describe the associated Bethe algebra Bq(KT(T∗Fλ)) by generators and relations in terms of a discrete Wronski map. We prove that the limiting Bethe algebra B∞(KT(T∗Fλ)) , called the Gelfand-Zetlin algebra, coincides with the algebra of multiplication operators of the algebra KT(T∗Fλ) . We conjecture that the Bethe algebra Bq(KT(T∗Fλ)) coincides with the algebra of quantum multiplication on KT(T∗Fλ) introduced by Givental (2000), Givental and Lee (2003). The stable envelope maps are defined with the help of Newton polygons of Laurent polynomials representing elements of KT(T∗Fλ) and with the help of the trigonometric weight functions introduced in Varchenko and Tarasov (1994), Tarasov and Varchenko (2013) to construct q-hypergeometric solutions of trigonometric qKZ equations. The paper has five appendices. In particular, in Appendix E we describe the Bethe algebra of the XXZ model by generators and relations.

  13. Ultrastructural observation of mesophyll cells and temporal expression profiles of the genes involved in transitory starch metabolism in flag leaves of wheat after anthesis.

    PubMed

    Kang, Guozhang; Peng, Xiaoqi; Wang, Lina; Yang, Yingying; Shao, Ruixin; Xie, Yingxin; Ma, Dongyun; Wang, Chenyang; Guo, Tiancai; Zhu, Yunji

    2015-01-01

    Transitory starch in cereal plant leaves is synthesized during the day and remobilized at night to provide a carbon source for growth and grain filling, but its mechanistic basis is still poorly understood. The objective of this study is to explore the regulatory mechanism for starch biosynthesis and degradation in plant source organs. Using transmission electron microscopy, we observed that during the day after anthesis, starch granules in mesophyll cells of wheat flag leaves accumulated in chloroplasts and the number of starch granules gradually decreased with wheat leaf growth. During the night, starch granules synthesized in chloroplasts during the day were completely or partially degraded. The transcript levels of 26 starch synthesis-related genes and 16 starch breakdown-related genes were further measured using quantitative real-time reverse transcription polymerase chain reaction. Expression profile analysis revealed that starch metabolism genes were clustered into two groups based on their temporal expression patterns. The genes in the first group were highly expressed and presumed to play crucial roles in starch metabolism. The genes in the other group were not highly expressed in flag leaves and may have minor functions in starch metabolism in leaf tissue. The functions of most of these genes in leaves were further discussed. The starch metabolism-related genes that are predominantly expressed in wheat flag leaves differ from those expressed in wheat grain, indicating that two different pathways for starch metabolism operate in these tissues. This provides specific information on the molecular mechanisms of transitory starch metabolism in higher plants.

  14. Comparative proteomic analysis of a membrane-enriched fraction from flag leaves reveals responses to chemical hybridization agent SQ-1 in wheat

    PubMed Central

    Song, Qilu; Wang, Shuping; Zhang, Gaisheng; Li, Ying; Li, Zheng; Guo, Jialin; Niu, Na; Wang, Junwei; Ma, Shoucai

    2015-01-01

    The induction of wheat male fertile lines by using the chemical hybridizing agent SQ-1 (CHA-SQ-1) is an effective approach in the utilization of heterosis; however, the molecular basis of male fertility remains unknown. Wheat flag leaves are the initial receptors of CHA-SQ-1 and their membrane structure plays a vital role in response to CHA-SQ-1 stress. To investigate the response of wheat flag leaves to CHA-SQ-1 stress, we compared their quantitative proteomic profiles in the absence and presence of CHA-SQ-1. Our results indicated that wheat flag leaves suffered oxidative stress during CHA-SQ-1 treatments. Leaf O2-, H2O2, and malonaldehyde levels were significantly increased within 10 h after CHA-SQ-1 treatment, while the activities of major antioxidant enzymes such as superoxide dismutase, catalase, and guaiacol peroxidase were significantly reduced. Proteome profiles of membrane-enriched fraction showed a change in the abundance of a battery of membrane proteins involved in multiple biological processes. These variable proteins mainly impaired photosynthesis, ATP synthesis protein mechanisms and were involved in the response to stress. These results provide an explanation of the relationships between membrane proteomes and anther abortion and the practical application of CHA for hybrid breeding. PMID:26379693

  15. Using Claims Data to Generate Clinical Flags Predicting Short-term Risk of Continued Psychiatric Hospitalizations

    PubMed Central

    Stein, Bradley D.; Pangilinan, Maria; Sorbero, Mark J; Marcus, Sue; Donahue, Sheila; Xu, Yan; Smith, Thomas E; Essock, Susan M

    2014-01-01

    Objective As health information technology advances, efforts to use administrative data to inform real-time treatment planning for individuals are increasing, despite few empirical studies demonstrating that such administrative data predict subsequent clinical events. Medicaid claims for individuals with frequent psychiatric hospitalizations were examined to test how well patterns of service use predict subsequent high short-term risk of continued psychiatric hospitalizations. Methods Medicaid claims files from New York and Pennsylvania were used to identify Medicaid recipients aged 18-64 with two or more inpatient psychiatric admissions during a target year ending March 31, 2009. Definitions from a quality-improvement initiative were used to identify patterns of inpatient and outpatient service use and prescription fills suggestive of clinical concerns. Generalized estimating equations and Markov models were applied to examine claims through March, 2011, to see what patterns of service use were sufficiently predictive of additional hospitalizations to be clinically useful. Results 11,801 unique individuals in New York and 1,859 in Pennsylvania identified met the cohort definition. In both Pennsylvania and New York, multiple recent hospitalizations, but not failure to use outpatient services or failure to fill medication prescriptions, were significant predictors of high risk of continued frequent hospitalizations, with odds ratios greater than 4.0. Conclusions Administrative data can be used to identify individuals at high risk of continued frequent hospitalizations. Such information could be used by payers and system administrators to authorize special services (e.g., mobile outreach) for such individuals as part of efforts to promote service engagement and prevent rapid rehospitalizations. PMID:25022360

  16. Raising a Red Flag on Dating Violence: Evaluation of a Low-Resource, College-Based Bystander Behavior Intervention Program.

    PubMed

    Borsky, Amanda E; McDonnell, Karen; Turner, Monique Mitchell; Rimal, Rajiv

    2016-03-09

    Encouraging bystanders to intervene safely and effectively in situations that could escalate to violence-known as bystander behavior programs-is a growing yet largely untested strategy to prevent dating violence. Using a quasi-experimental design, we evaluate a low-resource, low-intensity intervention aimed at preventing dating violence among college students. The integrated behavioral model (IBM) was used to guide the evaluation. We also assess which IBM variables were most strongly associated with bystander behaviors. Participants were drawn from two Virginia colleges that predominantly train females in the health profession sciences. The intervention group (n = 329) participated in a university-wide bystander behavior intervention consisting of a 30-min presentation on dating violence at new-student orientation and a week-long "red flag" social marketing campaign on campus to raise awareness of dating violence. Controlling for changes at the comparison university, results showed an increase in bystander behaviors, such as encouraging a friend who may be in an abusive relationship to get help, after the intervention and adjusting for potential confounders (increase of 1.41 bystander behaviors, p = .04). However, no significant changes were found for bystander intentions, self-efficacy, social norms, or attitudes related to dating violence from pre- to post-intervention. Self-efficacy had a direct relationship with bystander behaviors. Results suggest that low-resource interventions have a modest effect on increasing bystander behaviors. However, higher resource interventions likely are needed for a larger impact, especially among students who already demonstrate strong baseline intentions to intervene and prevent dating violence.

  17. China Report, Red Flag.

    DTIC Science & Technology

    1983-06-06

    century German chemist Justus Liebig had said: "Chemistry is moving forward at an incredible speed, and chemists, wishing to keep up with it, are...as complete as possible a ’moulting,’ as Liebig calls it, in mathematics and natural sciences.ൔ What was meant by this "moulting"? The famous 19th

  18. Italy flags scientific shortcomings

    NASA Astrophysics Data System (ADS)

    Cartlidge, Edwin

    2008-04-01

    The land that gave us Leonardo da Vinci, Galileo Galilei and Enrico Fermi does not regard science as part of culture, but it must do so if it is to avoid being left behind economically and intellectually. That is the message from a working group of 18 academics, sponsored by the Italian government, to find ways of improving the quantity, quality and public perception of science in the country. The group has now put forward a range of measures to combat what the group's chair, left-wing politician and Siena University law professor Luigi Berlinguer, describes as a "national emergency".

  19. Identification of novel quantitative trait loci for days to ear emergence and flag leaf glaucousness in a bread wheat (Triticum aestivum L.) population adapted to southern Australian conditions.

    PubMed

    Bennett, Dion; Izanloo, Ali; Edwards, James; Kuchel, Haydn; Chalmers, Ken; Tester, Mark; Reynolds, Matthew; Schnurbusch, Thorsten; Langridge, Peter

    2012-03-01

    In southern Australia, where the climate is predominantly Mediterranean, achieving the correct flowering time in bread wheat minimizes the impact of in-season cyclical and terminal drought. Flag leaf glaucousness has been hypothesized as an important component of drought tolerance but its value and genetic basis in locally adapted germplasm is unknown. From a cross between Kukri and RAC875, a doubled-haploid (DH) population was developed. A genetic linkage map consisting of 456 DArT and SSR markers was used to detect QTL affecting time to ear emergence and Zadoks growth score in seven field experiments. While ear emergence time was similar between the parents, there was significant transgressive segregation in the population. This was the result of segregation for the previously characterized Ppd-D1a and Ppd-B1 photoperiod responsive alleles. QTL of smaller effect were also detected on chromosomes 1A, 4A, 4B, 5A, 5B, 7A and 7B. A novel QTL for flag leaf glaucousness of large, repeatable effect was detected in six field experiments, on chromosome 3A (QW.aww-3A) and accounted for up to 52 percent of genetic variance for this trait. QW.aww-3A was validated under glasshouse conditions in a recombinant inbred line population from the same cross. The genetic basis of time to ear emergence in this population will aid breeders' understanding of phenological adaptation to the local environment. Novel loci identified for flag leaf glaucousness and the wide phenotypic variation within the DH population offers considerable scope to investigate the impact and value of this trait for bread wheat production in southern Australia.

  20. Natural Variation in the Flag Leaf Morphology of Rice Due to a Mutation of the NARROW LEAF 1 Gene in Oryza sativa L.

    PubMed

    Taguchi-Shiobara, Fumio; Ota, Tatsuya; Ebana, Kaworu; Ookawa, Taiichiro; Yamasaki, Masanori; Tanabata, Takanari; Yamanouchi, Utako; Wu, Jianzhong; Ono, Nozomi; Nonoue, Yasunori; Nagata, Kazufumi; Fukuoka, Shuichi; Hirabayashi, Hideyuki; Yamamoto, Toshio; Yano, Masahiro

    2015-10-01

    We investigated the natural variations in the flag leaf morphology of rice. We conducted a principal component analysis based on nine flag leaf morphology traits using 103 accessions from the National Institute of Agrobiological Sciences Core Collection. The first component explained 39% of total variance, and the variable with highest loading was the width of the flag leaf (WFL). A genome-wide association analysis of 102 diverse Japanese accessions revealed that marker RM6992 on chromosome 4 was highly associated with WFL. In analyses of progenies derived from a cross between Takanari and Akenohoshi, the most significant quantitative trait locus (QTL) for WFL was in a 10.3-kb region containing the NARROW LEAF 1 (NAL1) gene, located 0.4 Mb downstream of RM6992. Analyses of chromosomal segment substitution lines indicated that a mutation (G1509A single-nucleotide mutation, causing an R233H amino acid substitution in NAL1) was present at the QTL. This explained 13 and 20% of total variability in WFL and the distance between small vascular bundles, respectively. The mutation apparently occurred during rice domestication and spread into japonica, tropical japonica, and indica subgroups. Notably, one accession, Phulba, had a NAL1 allele encoding only the N-terminal, or one-fourth, of the wild-type peptide. Given that the Phulba allele and the histidine-type allele showed essentially the same phenotype, the histidine-type allele was regarded as malfunctional. The phenotypes of transgenic plants varied depending on the ratio of histidine-type alleles to arginine-type alleles, raising the possibility that H(233)-type products function differently from and compete with R(233)-type products.

  1. Natural Variation in the Flag Leaf Morphology of Rice Due to a Mutation of the NARROW LEAF 1 Gene in Oryza sativa L.

    PubMed Central

    Taguchi-Shiobara, Fumio; Ota, Tatsuya; Ebana, Kaworu; Ookawa, Taiichiro; Yamasaki, Masanori; Tanabata, Takanari; Yamanouchi, Utako; Wu, Jianzhong; Ono, Nozomi; Nonoue, Yasunori; Nagata, Kazufumi; Fukuoka, Shuichi; Hirabayashi, Hideyuki; Yamamoto, Toshio; Yano, Masahiro

    2015-01-01

    We investigated the natural variations in the flag leaf morphology of rice. We conducted a principal component analysis based on nine flag leaf morphology traits using 103 accessions from the National Institute of Agrobiological Sciences Core Collection. The first component explained 39% of total variance, and the variable with highest loading was the width of the flag leaf (WFL). A genome-wide association analysis of 102 diverse Japanese accessions revealed that marker RM6992 on chromosome 4 was highly associated with WFL. In analyses of progenies derived from a cross between Takanari and Akenohoshi, the most significant quantitative trait locus (QTL) for WFL was in a 10.3-kb region containing the NARROW LEAF 1 (NAL1) gene, located 0.4 Mb downstream of RM6992. Analyses of chromosomal segment substitution lines indicated that a mutation (G1509A single-nucleotide mutation, causing an R233H amino acid substitution in NAL1) was present at the QTL. This explained 13 and 20% of total variability in WFL and the distance between small vascular bundles, respectively. The mutation apparently occurred during rice domestication and spread into japonica, tropical japonica, and indica subgroups. Notably, one accession, Phulba, had a NAL1 allele encoding only the N-terminal, or one-fourth, of the wild-type peptide. Given that the Phulba allele and the histidine-type allele showed essentially the same phenotype, the histidine-type allele was regarded as malfunctional. The phenotypes of transgenic plants varied depending on the ratio of histidine-type alleles to arginine-type alleles, raising the possibility that H233-type products function differently from and compete with R233-type products. PMID:26275424

  2. Electron microscopy and in vitro deneddylation reveal similar architectures and biochemistry of isolated human and Flag-mouse COP9 signalosome complexes

    SciTech Connect

    Rockel, Beate; Schmaler, Tilo; Huang, Xiaohua; Dubiel, Wolfgang

    2014-07-25

    Highlights: • Deneddylation rates of human erythrocyte and mouse fibroblast CSN are very similar. • 3D models of native human and mouse CSN reveal common architectures. • The cryo-structure of native mammalian CSN shows a horseshoe subunit arrangement. - Abstract: The COP9 signalosome (CSN) is a regulator of the ubiquitin (Ub) proteasome system (UPS). In the UPS, proteins are Ub-labeled for degradation by Ub ligases conferring substrate specificity. The CSN controls a large family of Ub ligases called cullin-RING ligases (CRLs), which ubiquitinate cell cycle regulators, transcription factors and DNA damage response proteins. The CSN possesses structural similarities with the 26S proteasome Lid complex and the translation initiation complex 3 (eIF3) indicating similar ancestry and function. Initial structures were obtained 14 years ago by 2D electron microscopy (EM). Recently, first 3D molecular models of the CSN were created on the basis of negative-stain EM and single-particle analysis, mostly with recombinant complexes. Here, we compare deneddylating activity and structural features of CSN complexes purified in an elaborate procedure from human erythrocytes and efficiently pulled down from mouse Flag-CSN2 B8 fibroblasts. In an in vitro deneddylation assay both the human and the mouse CSN complexes deneddylated Nedd8-Cul1 with comparable rates. 3D structural models of the erythrocyte CSN as well as of the mouse Flag-CSN were generated by negative stain EM and by cryo-EM. Both complexes show a central U-shaped segment from which several arms emanate. This structure, called the horseshoe, is formed by the PCI domain subunits. CSN5 and CSN6 point away from the horseshoe. Compared to 3D models of negatively stained CSN complexes, densities assigned to CSN2 and CSN4 are better defined in the cryo-map. Because biochemical and structural results obtained with CSN complexes isolated from human erythrocytes and purified by Flag-CSN pulldown from mouse B8 fibroblasts

  3. On-line Flagging of Anomalies and Adaptive Sequential Hypothesis Testing for Fine-feature Characterization of Geosynchronous Satellites

    NASA Astrophysics Data System (ADS)

    Chaudhary, A.; Payne, T.; Kinateder, K.; Dao, P.; Beecher, E.; Boone, D.; Elliott, B.

    The objective of on-line flagging in this paper is to perform interactive assessment of geosynchronous satellites anomalies such as cross-tagging of a satellites in a cluster, solar panel offset change, etc. This assessment will utilize a Bayesian belief propagation procedure and will include automated update of baseline signature data for the satellite, while accounting for the seasonal changes. Its purpose is to enable an ongoing, automated assessment of satellite behavior through its life cycle using the photometry data collected during the synoptic search performed by a ground or space-based sensor as a part of its metrics mission. The change in the satellite features will be reported along with the probabilities of Type I and Type II errors. The objective of adaptive sequential hypothesis testing in this paper is to define future sensor tasking for the purpose of characterization of fine features of the satellite. The tasking will be designed in order to maximize new information with the least number of photometry data points to be collected during the synoptic search by a ground or space-based sensor. Its calculation is based on the utilization of information entropy techniques. The tasking is defined by considering a sequence of hypotheses in regard to the fine features of the satellite. The optimal observation conditions are then ordered in order to maximize new information about a chosen fine feature. The combined objective of on-line flagging and adaptive sequential hypothesis testing is to progressively discover new information about the features of a geosynchronous satellites by leveraging the regular but sparse cadence of data collection during the synoptic search performed by a ground or space-based sensor. Automated Algorithm to Detect Changes in Geostationary Satellite's Configuration and Cross-Tagging Phan Dao, Air Force Research Laboratory/RVB By characterizing geostationary satellites based on photometry and color photometry, analysts can

  4. The qTSN4 Effect on Flag Leaf Size, Photosynthesis and Panicle Size, Benefits to Plant Grain Production in Rice, Depending on Light Availability

    PubMed Central

    Fabre, Denis; Adriani, Dewi E.; Dingkuhn, Michael; Ishimaru, Tsutomu; Punzalan, Bermenito; Lafarge, Tanguy; Clément-Vidal, Anne; Luquet, Delphine

    2016-01-01

    Increasing rice yield potential is essential to secure world food supply. The quantitative trait locus qTSN4 was reported to achieve yield increases by enhancing both source and sink capacity. Three greenhouse experiments and one field experiment in the Philippines were conducted to study near-isogenic lines (NILs) in two genetic backgrounds, subjected to treatments with restricted light resources through shading (greenhouse) or population density (field and greenhouse). A consistent promotion of flag leaf width, leaf area and panicle size in terms of spikelet number was observed in the presence of qTSN4, regardless of environment. However, grain production per plant was enhanced only in one greenhouse experiment. An in-depth study demonstrated that increased flag leaf size in the presence of qTSN4 was associated with increased photosynthetic rates, along with lower SLA and greater N content per leaf weight and per area. This was emphasized under low light situation as the qTSN4-NILs did not express shade acclimation traits in contrast with the recipient varieties. The authors conclude that qTSN4 is a promising subject for further physiological studies, particularly under limited radiation. However, the QTL alone may not be a reliable source of increased yield potential because its effects at the plant and population scale are prone to genotype × environment interactions and the increased panicle size is compensated by the adaptive plasticity of other morphological traits. PMID:27242827

  5. Combination treatment of flag with non-pegylated liposomal doxorubicin (MYOCET(TM)) in elderly patients with acute myeloid leukemia: a single center experience.

    PubMed

    Melillo, Lorella; Valente, D; D'Arena, G; Dell'Olio, M; Falcone, A; Minervini, M M; Nobile, M; Rossi, G; Sanpaolo, G; Scalzulli, P R; Cascavilla, N

    2011-01-01

    The incidence of acute myeloid leukemia (AML) increases with age, but results of intensive chemotherapy in elderly patients are disappointing. Non-pegylated liposomal formulations of doxorubicin (Myocet™) have been developed with the aim of reducing systemic and cardiac toxicity especially in the elderly. We evaluated the efficacy and toxicity profiles of fludarabine, cytarabine and granulocyte colony-stimulating factor (FLAG) regimen given in association with Myocet™ in 35 patients with AML, median age 69 years (range 61-83 years). Nineteen (54.3%) had newly-diagnosed AML, twelve (34.3%) patients had secondary AML (ten with Myelodisplastic Syndrome, two with Primary Myelofibrosis) and 4 (11.4%) patients had had a late relapse (>12 months) of AML. Complete remission (CR) and partial remission (PR) were obtained in twenty-two (63%) and 3 (8.5%) patients, respectively. Seven (20%) patients showed a resistant disease. There were 3 early deaths (8.5%). Six patients (17%) experienced severe cardiovascular toxicity. The median overall survival (OS) was 12 months (range 1-52 months) with a median disease-free survival (DFS) of 20 months (range 1-48 months). One-year and two-year DFS were 78.9% and 26.7%, respectively. This study demonstrates that in elderly patients with AML, FLAG-Myocet combination shows promising efficacy response with acceptable toxicity, enabling most patients to receive further treatments, including transplantation procedures.

  6. [Effects of nitrogen supply on flag leaf photosynthesis and grain starch accumulation of wheat from its anthesis to maturity under drought or waterlogging].

    PubMed

    Fan, Xuemei; Jiang, Dong; Dai, Tingbo; Jing, Qi; Cao, Weixing

    2005-10-01

    In this paper, a cement pool culture experiment with three water treatments (waterlogging, drought, and moderate water supply) and two nitrogen levels (120 and 240 kg x hm(-2)) was conducted to study the effects of nitrogen supply on the flag leaf photosynthesis and grain starch accumulation of two wheat varieties from anthesis to maturity under soil drought and waterlogging. In comparing with moderate water supply, soil drought and waterlogging reduced the photosynthesis rate (Pn) and SPAD of flag leaf and dry matter accumulation. Nitrogen supply under drought increased Pn and SPAD, while that under waterlogging was in adverse. The total soluble sugar content in grain was reduced under both drought and waterlogging, while that in leaf was decreased under waterlogging but increased under drought. Under waterlogging, increasing nitrogen application rate reduced starch accumulation. The unit grain weight and the yields of grain and starch were reduced under both drought and waterlogging, but nitrogen application favored them under drought while in adverse under waterlogging. It was indicated that both leaf photosynthesis and grain starch accumulation could be regulated by nitrogen supply under stress of soil drought or waterlogging from anthesis to maturity of wheat.

  7. Copy Number Variation of Cytokinin Oxidase Gene Tackx4 Associated with Grain Weight and Chlorophyll Content of Flag Leaf in Common Wheat.

    PubMed

    Chang, Cheng; Lu, Jie; Zhang, Hai-Ping; Ma, Chuan-Xi; Sun, Genlou

    2015-01-01

    As the main pigment in photosynthesis, chlorophyll significantly affects grain filling and grain weight of crop. Cytokinin (CTK) can effectively increase chlorophyll content and chloroplast stability, but it is irreversibly inactivated by cytokinin oxidase (CKX). In this study, therefore, twenty-four pairs of primers were designed to identify variations of wheat CKX (Tackx) genes associated with flag leaf chlorophyll content after anthesis, as well as grain weight in 169 recombinant inbred lines (RIL) derived from Triticum aestivum Jing 411 × Hongmangchun 21. Results indicated variation of Tackx4, identified by primer pair T19-20, was proven to significantly associate with chlorophyll content and grain weight in the RIL population. Here, two Tackx4 patterns were identified: one with two co-segregated fragments (Tackx4-1/Tackx4-2) containing 618 bp and 620 bp in size (as in Jing 411), and another with no PCR product. The two genotypes were designated as genotype-A and genotype-B, respectively. Grain weight and leaf chlorophyll content at 5~15 days after anthesis (DAA) were significantly higher in genotype-A lines than those in genotype-B lines. Mapping analysis indicated Tackx4 was closely linked to Xwmc169 on chromosome 3AL, as well as co-segregated with a major quantitative trait locus (QTL) for both grain weight and chlorophyll content of flag leaf at 5~15 DAA. This QTL explained 8.9~22.3% phenotypic variations of the two traits across four cropping seasons. Among 102 wheat varieties, a third genotype of Tackx4 was found and designated as genotype-C, also having two co-segregated fragments, Tackx4-2 and Tackx4-3 (615bp). The sequences of three fragments, Tackx4-1, Tackx4-2, and Tackx4-3, showed high identity (>98%). Therefore, these fragments could be considered as different copies at Tackx4 locus on chromosome 3AL. The effect of copy number variation (CNV) of Tackx4 was further validated. In general, genotype-A contains both significantly higher grain weight

  8. Classification of psychosocial risk factors (yellow flags) for the development of chronic low back and leg pain using artificial neural network.

    PubMed

    Hallner, Dirk; Hasenbring, Monika

    2004-05-06

    Due to international guidelines of treatment of acute low back pain (LBP), psychosocial risk factors like depressive mood and maladaptive pain-related coping strategies ('yellow flags') have to be assessed in the early phase of acute pain. Within this longitudinal study in patients with LBP and leg pain, we used an artificial neural network (ANN) to classify the pain intensity 6 months after the onset of treatment. Psychosocial risk factors were used as input neurons. The training of the three-layer ANN using the back-propagation algorithm yields to an accuracy of 83.1%. Further on, the complexity of this structure indicated the necessity of an early screening procedure that allows a differentiation between several high risk groups and a low risk profile in order to predict the long-term development of pain intensity.

  9. Pre-anthesis high-temperature acclimation alleviates damage to the flag leaf caused by post-anthesis heat stress in wheat.

    PubMed

    Wang, Xiao; Cai, Jian; Jiang, Dong; Liu, Fulai; Dai, Tingbo; Cao, Weixing

    2011-04-15

    The objective of this study was to investigate the effect of pre-anthesis high-temperature acclimation on leaf physiology of winter wheat in response to post-anthesis heat stress. The results showed that both pre- and post-anthesis heat stresses significantly depressed flag leaf photosynthesis and enhanced cell membrane peroxidation, as exemplified by increased O₂⁻(·) production rate and reduction in activities of antioxiditave enzymes. However, under post-anthesis heat stress, plants with pre-anthesis high-temperature acclimation (HH) showed much higher photosynthetic rates than those without pre-anthesis high-temperature acclimation (CH). Leaves of HH plants exhibited a higher Chl a/b ratio and lower chlorophyll/carotenoid ratio and superoxide anion radical release rate compared with those of the CH plants. In addition, antioxidant enzyme activities in HH plants were significantly higher than in CH. Coincidently, expressions of photosythesis-responsive gene encoding Rubisco activase B (RcaB) and antioxidant enzyme-related genes encoding mitochondrial manganese superoxide dismutase (Mn-SOD), chloroplastic Cu/Zn superoxide dismutase (Cu/Zn-SOD), catalase (CAT) and cytosolic glutathione reductase (GR) were all up-regulated under HH, whereas a gene encoding a major chlorophyll a/b-binding protein (Cab) was up-regulated by post-anthesis heat stress at 10 DAA, but was down-regulated at 13 DAA. The changes in the expression levels of the HH plants were more pronounced than those for the CH. Collectively, the results indicated that pre-anthesis high-temperature acclimation could effectively alleviate the photosynthetic and oxidative damage caused by post-anthesis heat stress in wheat flag leaves, which was partially attributable to modifications in the expression of the photosythesis-responsive and antioxidant enzymes-related genes.

  10. UPLC-QTOF analysis reveals metabolomic changes in the flag leaf of wheat (Triticum aestivum L.) under low-nitrogen stress.

    PubMed

    Zhang, Yang; Ma, Xin-Ming; Wang, Xiao-Chun; Liu, Ji-Hong; Huang, Bing-Yan; Guo, Xiao-Yang; Xiong, Shu-Ping; La, Gui-Xiao

    2017-02-01

    Wheat is one of the most important grain crop plants worldwide. Nitrogen (N) is an essential macronutrient for the growth and development of wheat and exerts a marked influence on its metabolites. To investigate the influence of low nitrogen stress on various metabolites of the flag leaf of wheat (Triticum aestivum L.), a metabolomic analysis of two wheat cultivars under different induced nitrogen levels was conducted during two important growth periods based on large-scale untargeted metabolomic analysis using ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-QTOF). Multivariate analyses-such as principle components analysis (PCA) and orthogonal partial least square discriminant analysis (OPLS-DA)-were used for data analysis. PCA yielded distinctive clustering information among the samples, classifying the wheat flag samples into two categories: those under normal N treatment and low N treatment. By processing OPLS-DA, eleven secondary metabolites were shown to be responsible for classifying the two groups. The secondary metabolites may be considered potential biomarkers of low nitrogen stress. Chemical analyses showed that most of the identified secondary metabolites were flavonoids and their related derivatives, such as iso-vitexin, iso-orientin and methylisoorientin-2″-O-rhamnoside, etc. This study confirmed the effect of low nitrogen stress on the metabolism of wheat, and revealed that the accumulation of secondary metabolites is a response to abiotic stresses. Meanwhile, we aimed to identify markers which could be used to monitor the nitrogen status of wheat crops, presumably to guide appropriate fertilization regimens. Furthermore, the UPLC-QTOF metabolic platform technology can be used to study metabolomic variations of wheat under abiotic stresses.

  11. [Effects of drought and waterlogging on flag leaf post-anthesis photosynthetic characteristics and assimilates translocation in winter wheat under high temperature].

    PubMed

    Zhao, Hui; Dai, Ting-bo; Jiang, Dong; Jing, Qi; Cao, Wei-xing

    2007-02-01

    With winter wheat varieties Yangmai 9 and Yumai 34 as test materials, this paper studied post-anthesis photosynthetic characteristics in flag leaves, the translocation of assimilates and nitrogen stored in vegetative organs before and after anthesis and their relationships with grain yield and quality under different temperature and water conditions. The results showed that high temperature, drought, and waterlogging all had significant negative effects on photosynthetic rate and chlorophyll content (SPAD value) of flag leaves, and the effects of drought and waterlogging were greater under high temperature than under optimum temperature. The translocation amount and rate of assimilates and nitrogen stored in vegetative organs before anthesis declined in the order of drought > normal soil moisture content > waterlogging under optimum temperature, but normal soil moisture content > drought > waterlogging under high temperature. The amount of post-anthesis assimilates translocated into grain declined in the order of normal soil moisture content > waterlogging > drought under optimum temperature, but normal soil moisture content > drought > waterlogging under high temperature, while that of post-anthesis accumulated nitrogen declined in the order of normal soil moisture content > waterlogging > drought under both high and optimum temperature. The starch and protein contents in grains were the lowest under high temperature x waterlogging, but the highest under optimum temperature x normal soil moisture content. Overall, the decrease of grain mass and starch content under high temperature and water stresses was associated with the lower photosynthetic rate and less post-anthesis assimilates accumulation, while grain protein content was related to the translocation amount and rate of nitrogen stored before anthesis.

  12. Association of puroindoline b-2 variants with grain traits, yield components and flag leaf size in bread wheat (Triticum aestivum L.) varieties of Yellow and Huai Valley of China

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A total of 169 wheat (Triticum aestivum L.) varieties (landraces and cultivars) were used to asses the relationship between Puroindoline D1 alleles and Puroindoline b-B2 variants and grain hardness, other grain traits, grain yield components, and flag leaf size. Results indicated that the average SK...

  13. On-line Flagging of Anomalies and Adaptive Sequential Hypothesis Testing for Fine-feature Characterization of Geosynchronous Satellites

    DTIC Science & Technology

    2015-10-18

    University 3640 Colonel Glenn Hwy, Dayton, OH 45435 3 Air Force Research Laboratory Space Vehicles Directorate Kirtland AFB, Albuquerque, NM 87117...Research Laboratory and Space Vehicles Directorate ( AFRL /RV). Its foundation is the support provided by the Small Business Innovative Research Program...SBIR) at the AFRL Sensors Directorate ( AFRL /RY). Applied Optimization, Inc. gratefully acknowledges this support. 67 AMOS Technical Conference 2015

  14. The Applied Mathematics Laboratory.

    ERIC Educational Resources Information Center

    Siegel, Martha J.

    This report describes the Applied Mathematics Laboratory (AML) operated by the Department of Mathematics at Towson State University, Maryland. AML is actually a course offered to selected undergraduates who are given the opportunity to apply their skills in investigating industrial and governmental problems. By agreement with sponsoring…

  15. Applied Physics at Strathclyde.

    ERIC Educational Resources Information Center

    Patterson, H.; Twidell, J. W.

    1979-01-01

    Outlines and describes the content of an applied physics course offered for the four year honors and the three year pass degrees. The course stresses three components: principal subjects, industrial projects, and subsidiary subjects. (GA)

  16. Compensation: How to Apply

    MedlinePlus

    ... Benefit Rates Education & Training Education & Training Home For Students Get Started Get Started Home Apply for Benefits ... make a claims decision. Learn more about VA's responsibilities for obtaining evidence to support your disability ... Directory EMAIL UPDATES Email Address Button ...

  17. Geomorphology: Pure and applied

    SciTech Connect

    Hart, M.G.

    1986-01-01

    The book summarizes the history of intellectual debate in geomorphology and describes modern developments both ''pure'' and ''applied.'' The history begins well before W.M. Davis and follows through to such debates as those concerned with the Pleistocene. Modern developments in pure geomorphology are cast in terms of chapters on form, process, materials, and methods analysis. The applied chapters concentrate on environmental hazards and resources, and their management.

  18. Applied Learning Networks (ALN)

    DTIC Science & Technology

    2007-01-01

    AFRL-IF-RS-TR-2007-7 Final Technical Report January 2007 APPLIED LEARNING NETWORKS (ALN) University of Southern California...any other person or corporation; or convey any rights or permission to manufacture, use, or sell any patented invention that may relate to them...1-0051 4. TITLE AND SUBTITLE APPLIED LEARNING NETWORKS (ALN) 5c. PROGRAM ELEMENT NUMBER 62301E 5d. PROJECT NUMBER T981 5e. TASK NUMBER US

  19. The qTSN Positive Effect on Panicle and Flag Leaf Size of Rice is Associated with an Early Down-Regulation of Tillering

    PubMed Central

    Adriani, Dewi E.; Lafarge, Tanguy; Dardou, Audrey; Fabro, Aubrey; Clément-Vidal, Anne; Yahya, Sudirman; Dingkuhn, Michael; Luquet, Delphine

    2016-01-01

    The qTSN4 was identified as rice QTL (Quantitative Traits Locus) increasing total spikelet number per panicle and flag leaf area but potentially reducing panicle number depending on the environment. So far, this trade-off was mainly observed at grain maturity and not specifically studied in details, limiting the apprehension of the agronomic interest of qTSN4. This study aimed to understand the effect of qTSN4 and of the environment on panicle sizing, its trade-off with panicle number, and finally plant grain production. It compared two high yielding genotypes to their Near Isogenic Lines (NIL) carrying either QTL qTSN4 or qTSN12, two distinct QTLs contributing to the enlarged panicle size, thereafter designated as qTSN. Traits describing C sink (organ appearance rate, size, biomass) and source (leaf area, photosynthesis, sugar availability) were dynamically characterized along plant and/or panicle development within two trials (greenhouse, field), each comparing two treatments contrasting for plant access to light (with or without shading, high or low planting densities). The positive effect of qTSN on panicle size and flag leaf area of the main tiller was confirmed. More precisely, it could be shown that qTSN increased leaf area and internode cross-section, and in some cases of the photosynthetic rate and starch reserves, of the top 3–4 phytomers of the main tiller. This was accompanied by an earlier tillering cessation, that coincided with the initiation of these phytomers, and an enhanced panicle size on the main tiller. Plant leaf area at flowering was not affected by qTSN but fertile tiller number was reduced to an extent that depended on the environment. Accordingly, plant grain production was enhanced by qTSN only under shading in the greenhouse experiment, where panicle number was not affected and photosynthesis and starch storage in internodes was enhanced. The effect of qTSN on rice phenotype was thus expressed before panicle initiation (PI). Whether

  20. [Effects of nitrogen application and elevated atmospheric CO2 on electron transport and energy partitioning in flag leaf photosynthesis of wheat].

    PubMed

    Zhang, Xu-cheng; Yu, Xian-feng; Ma, Yi-fan

    2011-03-01

    Wheat (Triticum aestivum) plants were pot-cultured in open top chambers at the nitrogen application rate of 0 and 200 mg x kg(-1) soil and the atmospheric CO2 concentration of 400 and 760 micromol x mol(-1). Through the determination of flag leaf nitrogen and chlorophyll contents, photosynthetic rate (Pn)-intercellar CO2 concentration (Ci) response curve, and chlorophyll fluorescence parameters at heading stage, the photosynthetic electron transport rate and others were calculated, aimed to investigate the effects of nitrogen application and elevated atmospheric CO2 concentration on the photosynthetic energy partitioning in wheat flag leaves. Elevated atmospheric CO2 concentration decreased the leaf nitrogen and chlorophyll contents, compared with the ambient one, and the chlorophyll a/b ratio increased at the nitrogen application rate of 200 mg x kg(-1). With the application of nitrogen, no evident variations were observed in the maximal photochemical efficiency (Fv/Fm), maximal quantum yield under irradiance (Fv'/Fm') of PS II reaction center, photochemical fluorescence quenching coefficient (q(p)), and actual PS II efficiency under irradiance (phi(PS II) at elevated atmospheric CO2 concentration, and the total photosynthetic electron transport rate (J(F)) of PS II reaction center had no evident increase, though the non-photochemical fluorescence quenching coefficient (NPQ) decreased significantly. With no nitrogen application, the Fv'/Fm', psi(PS II), and NPQ at elevated atmospheric CO2 concentration decreased significantly, and the J(F) had a significant decrease though the Fv/Fm and q(p) did not vary remarkably. Nitrogen application increased the J(F) and photochemical electron transport rate (Jc); while elevated atmospheric CO2 concentration decreased the photorespiration electron transport rate (J0), Rubisco oxidation rate (V0), ratio of photorespiration to photochemical electron transport rate (J0/Jc) , and Rubisco oxidation/carboxylation rate (Vo/Vc), but

  1. Accuracy Assessment of Aqua-MODIS Aerosol Optical Depth Over Coastal Regions: Importance of Quality Flag and Sea Surface Wind Speed

    NASA Technical Reports Server (NTRS)

    Anderson, J. C.; Wang, J.; Zeng, J.; Petrenko, M.; Leptoukh, G. G.; Ichoku, C.

    2012-01-01

    Coastal regions around the globe are a major source for anthropogenic aerosols in the atmosphere, but the underlying surface characteristics are not favorable for the Moderate Resolution Imaging Spectroradiometer (MODIS) algorithms designed for retrieval of aerosols over dark land or open-ocean surfaces. Using data collected from 62 coastal stations worldwide from the Aerosol Robotic Network (AERONET) from approximately 2002-2010, accuracy assessments are made for coastal aerosol optical depth (AOD) retrieved from MODIS aboard Aqua satellite. It is found that coastal AODs (at 550 nm) characterized respectively by the MODIS Dark Land (hereafter Land) surface algorithm, the Open-Ocean (hereafter Ocean) algorithm, and AERONET all exhibit a log-normal distribution. After filtering by quality flags, the MODIS AODs respectively retrieved from the Land and Ocean algorithms are highly correlated with AERONET (with R(sup 2) is approximately equal to 0.8), but only the Land algorithm AODs fall within the expected error envelope greater than 66% of the time. Furthermore, the MODIS AODs from the Land algorithm, Ocean algorithm, and combined Land and Ocean product show statistically significant discrepancies from their respective counterparts from AERONET in terms of mean, probability density function, and cumulative density function, which suggest a need for future improvement in retrieval algorithms. Without filtering with quality flag, the MODIS Land and Ocean AOD dataset can be degraded by 30-50% in terms of mean bias. Overall, the MODIS Ocean algorithm overestimates the AERONET coastal AOD by 0.021 for AOD less than 0.25 and underestimates it by 0.029 for AOD greater than 0.25. This dichotomy is shown to be related to the ocean surface wind speed and cloud contamination effects on the satellite aerosol retrieval. The Modern Era Retrospective-Analysis for Research and Applications (MERRA) reveals that wind speeds over the global coastal region 25 (with a mean and median

  2. Involvement of Abscisic Acid in PSII Photodamage and D1 Protein Turnover for Light-Induced Premature Senescence of Rice Flag Leaves

    PubMed Central

    Wang, Fubiao; Liu, Jianchao; Chen, Minxue; Zhou, Lujian; Li, Zhaowei; Zhao, Qian; Pan, Gang; Zaidi, Syed-Hassan-Raza; Cheng, Fangmin

    2016-01-01

    D1 protein in the PSII reaction center is the major target of photodamage, and it exhibits the highest turnover rate among all the thylakoid proteins. In this paper, rice psf (premature senescence of flag leaves) mutant and its wild type were used to investigate the genotype-dependent alteration in PSII photo-damage and D1 protein turnover during leaf senescence and its relation to ABA accumulation in senescent leaves. The symptom and extent of leaf senescence of the psf mutant appeared to be sunlight-dependent under natural field condition. The psf also displayed significantly higher levels of ABA accumulation in senescent leaves than the wild type. However, the premature senescence lesion of psf leaves could be alleviated by shaded treatment, concomitantly with the strikingly suppressed ABA level in the shaded areas of flag leaves. The change in ABA concentration contributed to the regulation of shade-delayed leaf senescence. The participation of ABA in the timing of senescence initiation and in the subsequent rate of leaf senescence was closely associated with PSII photodamage and D1 protein turnover during leaf senescence, in which the transcriptional expression of several key genes (psbA, psbB, psbC and OsFtsH2) involved in D1 protein biosynthesis and PSII repair cycle was seriously suppressed by the significantly increased ABA level. This response resulted in the low rate of D1 protein synthesis and impaired repair recovery in the presence of ABA. The psf showed evidently decreased D1 protein amount in the senescent leaves. Both the inhibition of de novo synthesized D1 protein and the slow rate of proteolytic removal for the photodamaged D1 protein was among the most crucial steps for the linkage between light-dependent leaf senescence and the varying ABA concentration in psf mutant leaves. OsFtsH2 transcriptional expression possibly played an important role in the regulation of D1 protein turnover and PSII repair cycle in relation to ABA mediated leaf

  3. PSYCHOANALYSIS AS APPLIED AESTHETICS.

    PubMed

    Richmond, Stephen H

    2016-07-01

    The question of how to place psychoanalysis in relation to science has been debated since the beginning of psychoanalysis and continues to this day. The author argues that psychoanalysis is best viewed as a form of applied art (also termed applied aesthetics) in parallel to medicine as applied science. This postulate draws on a functional definition of modernity as involving the differentiation of the value spheres of science, art, and religion. The validity criteria for each of the value spheres are discussed. Freud is examined, drawing on Habermas, and seen to have erred by claiming that the psychoanalytic method is a form of science. Implications for clinical and metapsychological issues in psychoanalysis are discussed.

  4. Global genome expression analysis of rice in response to drought and high-salinity stresses in shoot, flag leaf, and panicle

    PubMed Central

    Zhou, Junli; Wang, Xiangfeng; Jiao, Yuling; Qin, Yonghua; Liu, Xigang; He, Kun; Chen, Chen; Ma, Ligeng; Wang, Jian; Xiong, Lizhong; Zhang, Qifa; Fan, Liumin

    2007-01-01

    To elucidate genome-level responses to drought and high-salinity stress in rice, a 70mer oligomer microarray covering 36,926 unique genes or gene models was used to profile genome expression changes in rice shoot, flag leaf and panicle under drought or high-salinity conditions. While patterns of gene expression in response to drought or high-salinity stress within a particular organ type showed significant overlap, comparison of expression profiles among different organs showed largely organ-specific patterns of regulation. Moreover, both stresses appear to alter the expression patterns of a significant number of genes involved in transcription and cell signaling in a largely organ-specific manner. The promoter regions of genes induced by both stresses or induced by one stress in more than one organ types possess relative enrichment of two cis-elements (ABRE core and DRE core) known to be associated with water stress. An initial computational analysis indicated that novel promoter motifs are present in the promoters of genes involved in rehydration after drought. This analysis suggested that rice might possess a mechanism that actively detects rehydration and facilitates rapid recovery. Overall, our data supports a notion that organ-specific gene regulation in response to the two abiotic stresses may primarily be mediated by organ-specific transcription responses. Electronic supplementary material The online version of this article (doi:10.1007/s11103-006-9111-1) contains supplementary material, which is available to authorized users. PMID:17225073

  5. Flagging and correcting non-spectral matrix interferences with spatial emission profiles and gradient dilution in inductively coupled plasma-atomic emission spectrometry

    NASA Astrophysics Data System (ADS)

    Cheung, Yan; Schwartz, Andrew J.; Chan, George C.-Y.; Hieftje, Gary M.

    2015-08-01

    Matrix interference remains one of the most daunting challenges commonly encountered in inductively coupled plasma-atomic emission spectrometry (ICP-AES). In the present study, a method is described that enables identification and correction of matrix interferences in axial-viewed ICP-AES through a combination of spatial mapping and on-line gradient dilution. Cross-sectional emission maps of the plasma are used to indicate the presence of non-spectral (plasma-related and sample-introduction-related) matrix interferences. In particular, apparent concentrations of an analyte species determined at various radial locations in the plasma differ in the presence of a matrix interference, which allows the interference to be flagged. To correct for the interference, progressive, on-line dilution of the sample, performed by a gradient high-performance liquid-chromatograph pump, is utilized. The spatially dependent intensities of analyte emission are monitored at different levels of sample dilution. As the dilution proceeds, the matrix-induced signal variation is reduced. At a dilution where the determined concentrations become independent of location in the plasma, the matrix interference is minimized.

  6. Fine mapping of a major QTL for flag leaf width in rice, qFLW4, which might be caused by alternative splicing of NAL1.

    PubMed

    Chen, Mingliang; Luo, Ju; Shao, Gaoneng; Wei, Xiangjin; Tang, Shaoqing; Sheng, Zhonghua; Song, Jian; Hu, Peisong

    2012-05-01

    Leaf width is an important agricultural trait in rice. QTL mapping in a recombinant inbred line population derived from the cross between the javanica cultivar D50 (narrow-leaved) and the indica cultivar HB277 (wide-leaved) identified five QTLs controlling flag leaf width. Fine mapping of the major QTL qFLW4 narrowed its location to a 74.8 kb interval between the SSR loci RM17483 and RM17486, a region which also contains the gene NAL1 (Narrow leaf 1). There was no difference in the level of NAL1 expression between cvs. D50 and HB277, but an analysis of the NAL1 transcripts showed that while most (if not all) of those produced in cv. D50 were full-length, two-thirds of those in HB277 were non-functional due to either loss or gain of sequence. The inference was that NAL1 is probably synonymous with qFLW4, and that the functional difference between the two alleles was due to alternative splicing. The analysis of expression of other known genes involved in the determination of leaf width provided no evidence of their having any clear functional association with qFLW4/NAL1.

  7. Gene expression profiling of flag leaves at the booting stage in the japonica hybrid rice Huayou14 and its parental lines by microarray.

    PubMed

    Huangwei, Chu; Fuan, Niu; Can, Cheng; Jihua, Zhou; Xinqi, Wang; Xiaojin, Luo; Qin, Yuan; Liming, Cao

    2015-09-01

    Gene expression profiling using microarray has contributed significantly to heterosis studies. Using the Affymetrix rice genome array, we investigated gene expression profiles in the flag leaves of the japonica hybrid rice Huayou14 and its parental cultivars Shen9A and Fan14 at the booting stage. A total of 2057 genes differentially expressed (fold change ≥2 or ≤0.5) between Huayou14 and its parents were identified. Functional classification of the differentially expressed genes by Gene Ontology (GO) analysis indicated the differentially expressed genes were significantly enriched in photosynthesis-related cellular component categories (e.g. photosystem Ⅰ, chloroplast membrane and chloroplast envelope), and biological process categories (e.g. chlorophyll catabolic, chlorophyll biosynthetic and carotenoid biosynthetic processes). These results suggest that the changes in the photosynthetic ability of the japonica hybrid rice Huayou14 may be related to heterosis. Metabolic pathway analysis indicated that differentially expressed genes were significantly enriched in photosynthesis-antenna proteins and starch and sucrose metabolic pathways, instead of photosynthesis and carbon fixation pathways as reported previously. These results suggest that different genes or metabolic pathways might contribute to the heterosis of different hybrid combinations.

  8. Applied Music (Individual Study).

    ERIC Educational Resources Information Center

    Texas Education Agency, Austin.

    Background information and resources to help students in grades 9-12 in Texas pursue an individual study contract in applied music is presented. To fulfill a contract students must publicly perform from memory, with accompaniment as specified, three selections from a list of approved music for their chosen field (instrument or voice). Material…

  9. Applied Behavior Analysis

    ERIC Educational Resources Information Center

    Szapacs, Cindy

    2006-01-01

    Teaching strategies that work for typically developing children often do not work for those diagnosed with an autism spectrum disorder. However, teaching strategies that work for children with autism do work for typically developing children. In this article, the author explains how the principles and concepts of Applied Behavior Analysis can be…

  10. Signals: Applying Academic Analytics

    ERIC Educational Resources Information Center

    Arnold, Kimberly E.

    2010-01-01

    Academic analytics helps address the public's desire for institutional accountability with regard to student success, given the widespread concern over the cost of higher education and the difficult economic and budgetary conditions prevailing worldwide. Purdue University's Signals project applies the principles of analytics widely used in…

  11. Essays on Applied Microeconomics

    ERIC Educational Resources Information Center

    Mejia Mantilla, Carolina

    2013-01-01

    Each chapter of this dissertation studies a different question within the field of Applied Microeconomics. The first chapter examines the mid- and long-term effects of the 1998 Asian Crisis on the educational attainment of Indonesian children ages 6 to 18, at the time of the crisis. The effects are identified as deviations from a linear trend for…

  12. Applied Vocational Mathematics.

    ERIC Educational Resources Information Center

    South Carolina State Dept. of Education, Columbia. Office of Vocational Education.

    Developed for use in teaching a two-semester, one-unit course, this course guide is intended to aid the high school instructor in teaching mathematical problem-solving and computational skills to vocational education students. The state-adopted textbook for general mathematics III, "Applied General Mathematics" serves as the major…

  13. Applied Linguistics in Europe

    ERIC Educational Resources Information Center

    de Bot, Kees

    2004-01-01

    In this contribution developments in Applied Linguistics in Europe are linked to major social changes that have taken place over the last decades. These include: The decline of the USSR and the end of the cold war; The development of the EEC and the EU and fading of borders; The economic growth of Western Europe; Labor migration from the south to…

  14. Africa and Applied Linguistics.

    ERIC Educational Resources Information Center

    Makoni, Sinfree, Ed.; Meinhof, Ulrike H., Ed.

    2003-01-01

    This collection of articles includes: "Introducing Applied Linguistics in Africa" (Sinfree Makoni and Ulrike H. Meinhof); "Language Ideology and Politics: A Critical Appraisal of French as Second Official Language in Nigeria" (Tope Omoniyi); "The Democratisation of Indigenous Languages: The Case of Malawi" (Themba…

  15. Applied Algebra Curriculum Modules.

    ERIC Educational Resources Information Center

    Texas State Technical Coll., Marshall.

    This collection of 11 applied algebra curriculum modules can be used independently as supplemental modules for an existing algebra curriculum. They represent diverse curriculum styles that should stimulate the teacher's creativity to adapt them to other algebra concepts. The selected topics have been determined to be those most needed by students…

  16. Applied research on glucansucrases

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Although glycansucrases have been known for over 70 years, they remain relatively unknown except to a small group of researchers. Practical, applied research on glycansucrases has been focused on certain key areas. The earliest of these was the development of blood plasma extenders from dextran, d...

  17. Applied Statistics with SPSS

    ERIC Educational Resources Information Center

    Huizingh, Eelko K. R. E.

    2007-01-01

    Accessibly written and easy to use, "Applied Statistics Using SPSS" is an all-in-one self-study guide to SPSS and do-it-yourself guide to statistics. What is unique about Eelko Huizingh's approach is that this book is based around the needs of undergraduate students embarking on their own research project, and its self-help style is designed to…

  18. Quality in applied science

    NASA Astrophysics Data System (ADS)

    Sten, T.

    1993-12-01

    Science is in many senses a special kind of craft and only skilled craftsmen are able to distinguish good work from bad. Due to the variation in approaches, methods and even philosophical basis, it is nearly impossible to derive a general set of quality criteria for scientific work outside specific research traditions. Applied science introduces a new set of quality criteria having to do with the application of results in practical situations and policy making. A scientist doing basic research relates mainly to the scientific community of which he is a member, while in applied contract research the scientist has to consider the impact of his results both for the immediate users and upon interest groups possibly being affected. Application thus raises a whole new set of requirements having to do with business ethics, policy consequences and societal ethics in general.

  19. Applied Meteorology Unit (AMU)

    NASA Technical Reports Server (NTRS)

    Bauman, William; Lambert, Winifred; Wheeler, Mark; Barrett, Joe; Watson, Leela

    2007-01-01

    This report summarizes the Applied Meteorology Unit (AMU) activities for the second quarter of Fiscal Year 2007 (January - March 2007). Tasks reported on are: Obiective Lightning Probability Tool, Peak Wind Tool for General Forecasting, Situational Lightning Climatologies for Central Florida, Anvil Threat Corridor Forecast Tool in AWIPS, Volume Averaqed Heiqht lnteq rated Radar Reflectivity (VAHIRR), Tower Data Skew-t Tool, and Weather Research and Forecastini (WRF) Model Sensitivity Study

  20. Nanoengineering Applied to Tungsten

    DTIC Science & Technology

    2006-05-01

    and R. Z. Valiev ARL-RP- 123 May 2006 A reprint from the Proceedings of the Sixth International Conference on Tungsten, Refractory...Ground, MD 21005-5066 ARL-RP- 123 May 2006 Nanoengineering Applied to Tungsten Q. Wei University of North Carolina-Charlotte B. E...ORGANIZATION REPORT NUMBER ARL-RP- 123 10. SPONSOR/MONITOR’S ACRONYM(S) 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 11. SPONSOR

  1. Applied science. Introduction.

    PubMed

    Bud, Robert

    2012-09-01

    Such categories as applied science and pure science can be thought of as "ideological." They have been contested in the public sphere, exposing long-term intellectual commitments, assumptions, balances of power, and material interests. This group of essays explores the contest over applied science in Britain and the United States during the nineteenth century. The essays look at the concept in the context of a variety of neighbors, including pure science, technology, and art. They are closely related and connected to contemporary historiographic debate. Jennifer Alexander links the issues raised to a recent paper by Paul Forman. Paul Lucier and Graeme Gooday deal with the debates in the last quarter of the century in the United States and Britain, respectively. Robert Bud deals with the earlier part of the nineteenth century, with an eye specifically on the variety of concepts hybridized under the heading of "applied science." Eric Schatzberg looks at the erosion of the earlier concept of art. As a whole, the essays illuminate both long-term changes and nuanced debate and are themselves intended to provoke further reflection on science in the public sphere.

  2. Dorsoventral asymmetry of photosynthesis and photoinhibition in flag leaves of two rice cultivars that differ in nitrogen response and leaf angle.

    PubMed

    Kumagai, Etsushi; Hamaoka, Norimitsu; Araki, Takuya; Ueno, Osamu

    2014-08-01

    Rice is believed to show photosynthetic symmetry between adaxial and abaxial leaf sides. To verify this, we re-examined dorsoventral asymmetry in photosynthesis, chlorophyll fluorescence and anatomical traits in flag leaves of two Oryza sativa cultivars that differ in nitrogen (N) response and in leaf angle: 'Akenohoshi', a cultivar that can adapt to low-N (LN), with low leaf angle (more erect leaves), and 'Shirobeniya', a cultivar that is unable to adapt to LN, with higher leaf angle. Plants were grown under standard-N (SN) and LN conditions. LN leaves of both cultivars became more erect than SN, but LN Akenohoshi still had more erect ones than Shirobeniya. Contrary to results of previous studies, leaves of both cultivars showed an asymmetry in photosynthetic rate between adaxial and abaxial sides (higher on the adaxial side) under SN. SN leaves of both cultivars showed lower susceptibility to photoinhibition on the adaxial side than on the abaxial side. However, leaves of Akenohoshi showed less asymmetry in these traits under LN than under SN, whereas leaves of Shirobeniya had similar degrees of asymmetry in these traits under both SN and LN. Both cultivars also showed dorsoventral asymmetry in anatomical traits of mesophyll tissue regardless of N level, but the degree of asymmetry was lower in LN Akenohoshi. These data reveal that rice leaves exhibit dorsoventral asymmetry in photosynthetic and anatomical features, and that the degree of asymmetry varies with cultivar and N level. It is suggested that lower leaf angles (particularly in Akenohoshi) in the presence of LN represent a light acclimation to prevent photoinhibition.

  3. Members of the barley NAC transcription factor gene family show differential co-regulation with senescence-associated genes during senescence of flag leaves.

    PubMed

    Christiansen, Michael W; Gregersen, Per L

    2014-07-01

    The senescence process of plants is important for the completion of their life cycle, particularly for crop plants, it is essential for efficient nutrient remobilization during seed filling. It is a highly regulated process, and in order to address the regulatory aspect, the role of genes in the NAC transcription factor family during senescence of barley flag leaves was studied. Several members of the NAC transcription factor gene family were up-regulated during senescence in a microarray experiment, together with a large range of senescence-associated genes, reflecting the coordinated activation of degradation processes in senescing barley leaf tissues. This picture was confirmed in a detailed quantitative reverse transcription-PCR (qRT-PCR) experiment, which also showed distinct gene expression patterns for different members of the NAC gene family, suggesting a group of ~15 out of the 47 studied NAC genes to be important for signalling processes and for the execution of degradation processes during leaf senescence in barley. Seven models for DNA-binding motifs for NAC transcription factors were designed based on published motifs, and available promoter sequences of barley genes were screened for the motifs. Genes up-regulated during senescence showed a significant over-representation of the motifs, suggesting regulation by the NAC transcription factors. Furthermore, co-regulation studies showed that genes possessing the motifs in the promoter in general were highly co-expressed with members of the NAC gene family. In conclusion, a list of up to 15 NAC genes from barley that are strong candidates for being regulatory factors of importance for senescence and biotic stress-related traits affecting the productivity of cereal crop plants has been generated. Furthermore, a list of 71 senescence-associated genes that are potential target genes for these NAC transcription factors is presented.

  4. N-ICE plasmids for generating N-terminal 3 × FLAG tagged genes that allow inducible, constitutive or endogenous expression in Saccharomyces cerevisiae.

    PubMed

    Zhang, Yueping; Serratore, Nina D; Briggs, Scott D

    2016-12-12

    PCR-mediated homologous recombination is a powerful approach to introduce epitope tags into the chromosomal loci at the N-terminus or the C-terminus of targeted genes. Although strategies of C-terminal epitope tagging of target genes at their loci are simple and widely used in yeast, C-terminal epitope tagging is not practical for all proteins. For example, a C-terminal tag may affect protein function or a protein may get cleaved or processed, resulting in the loss of the epitope tag. Therefore, N-terminal epitope tagging may be necessary to resolve these problems. In some cases, an epitope tagging strategy is used to introduce a heterologous promoter with the epitope tag at the N-terminus of a gene of interest. The potential issue with this strategy is that the tagged gene is not expressed at the endogenous level. Another strategy after integration is to excise the selection marker, using the Cre-LoxP system, leaving the epitope tagged gene expressed from the endogenous promoter. However, N-terminal epitope tagging of essential genes using this strategy requires a diploid strain followed by tetrad dissection. Here we present 14 new plasmids for N-terminal tagging, which combines two previous strategies for epitope tagging in a haploid strain. These 'N-ICE' plasmids were constructed so that non-essential and essential genes can be N-terminally 3 × FLAG tagged and expressed from an inducible promoter (GAL1), constitutive promoters (CYC1 or PYK1) or the endogenous promoter. We have validated the N-ICE plasmid system by N-terminal tagging two non-essential genes (SET1 and SET2) and two essential genes (ERG11 and PKC1). Copyright © 2016 John Wiley & Sons, Ltd.

  5. Applied Meteorology Unit (AMU)

    NASA Technical Reports Server (NTRS)

    Bauman, William; Crawford, Winifred; Barrett, Joe; Watson, Leela; Wheeler, Mark

    2010-01-01

    This report summarizes the Applied Meteorology Unit (AMU) activities for the first quarter of Fiscal Year 2010 (October - December 2009). A detailed project schedule is included in the Appendix. Included tasks are: (1) Peak Wind Tool for User Launch Commit Criteria (LCC), (2) Objective Lightning Probability Tool, Phase III, (3) Peak Wind Tool for General Forecasting, Phase II, (4) Upgrade Summer Severe Weather Tool in Meteorological Interactive Data Display System (MIDDS), (5) Advanced Regional Prediction System (ARPS) Data Analysis System (ADAS) Update and Maintainability, (5) Verify 12-km resolution North American Model (MesoNAM) Performance, and (5) Hybrid Single-Particle Lagrangian Integrated Trajectory (HYSPLIT) Graphical User Interface.

  6. NASA Applied Sciences Program

    NASA Technical Reports Server (NTRS)

    Frederick, Martin

    2006-01-01

    This presentation highlights the NASA Applied Sciences Program. The goal of the program is to extend the results of scientific research and knowledge beyond the science community to contribute to NASA's partners' applications of national priority, such as agricultural efficiency, energy management and Homeland Security. Another purpose of the program's scientific research is to increase knowledge of the Earth-Sun system to enable improved predictions of climate, weather, and natural hazards. The program primarily optimizes benefits for citizens by contributing to partnering on applications that are used by state, local and tribal governments.

  7. Applied Meteorology Unit (AMU)

    NASA Technical Reports Server (NTRS)

    Bauman, William H., Jr.; Crawford, Winifred; Short, David; Barrett, Joe; Watson, Leela

    2008-01-01

    This report summarizes the Applied Meteorology Unit (AMU) activities for the second quarter of Fiscal Year 2008 (January - March 2008). Projects described are: (1) Peak Wind Tool for User Launch Commit Criteria (LCC), (2) Peak Wind Tool for General Forecasting, (3) Situational Lightning Climatologies for Central Florida. Phase III, (4) Volume Averaged Height Integrated Radar Reflectivity (VAHIRR), (5) Impact of Local Sensors, (6) Radar Scan Strategies for the PAFB WSR-74C Replacement and (7) WRF Wind Sensitivity Study at Edwards Air Force Base.

  8. Applied Impact Physics Research

    NASA Astrophysics Data System (ADS)

    Wickert, Matthias

    2013-06-01

    Applied impact physics research is based on the capability to examine impact processes for a wide range of impact conditions with respect to velocity as well as mass and shape of the projectile. For this reason, Fraunhofer EMI operates a large variety of launchers that address velocities up to ordnance velocities as single stage powder gun but which can also be operated as two-stage light gas guns achieving the regime of low earth orbital velocity. Thereby for projectile masses of up to 100 g hypervelocity impact phenomena up to 7.8 km/s can be addressed. Advanced optical diagnostic techniques like microsecond video are used as commercial systems but - since impact phenomena are mostly related with debris or dust - specialized diagnostics are developed in-house like x-ray cinematography and x-ray tomography. Selected topics of the field of applied impact physics will be presented like the interesting behavior of long rods penetrating low-density materials or experimental findings at hypervelocity for this class of materials as well as new x-ray diagnositic techniques.

  9. Applied Routh approximation

    NASA Technical Reports Server (NTRS)

    Merrill, W. C.

    1978-01-01

    The Routh approximation technique for reducing the complexity of system models was applied in the frequency domain to a 16th order, state variable model of the F100 engine and to a 43d order, transfer function model of a launch vehicle boost pump pressure regulator. The results motivate extending the frequency domain formulation of the Routh method to the time domain in order to handle the state variable formulation directly. The time domain formulation was derived and a characterization that specifies all possible Routh similarity transformations was given. The characterization was computed by solving two eigenvalue-eigenvector problems. The application of the time domain Routh technique to the state variable engine model is described, and some results are given. Additional computational problems are discussed, including an optimization procedure that can improve the approximation accuracy by taking advantage of the transformation characterization.

  10. NASA Applied Sciences Program

    NASA Technical Reports Server (NTRS)

    Estes, Sue M.; Haynes, J. A.

    2009-01-01

    NASA's strategic Goals: a) Develop a balanced overall program of science, exploration, and aeronautics consistent with the redirection of human spaceflight program to focus on exploration. b) Study Earth from space to advance scientific understanding and meet societal needs. NASA's partnership efforts in global modeling and data assimilation over the next decade will shorten the distance from observations to answers for important, leading-edge science questions. NASA's Applied Sciences program will continue the Agency's efforts in benchmarking the assimilation of NASA research results into policy and management decision-support tools that are vital for the Nation's environment, economy, safety, and security. NASA also is working with NOAH and inter-agency forums to transition mature research capabilities to operational systems, primarily the polar and geostationary operational environmental satellites, and to utilize fully those assets for research purposes.

  11. Applying robotics to HAZMAT

    NASA Technical Reports Server (NTRS)

    Welch, Richard V.; Edmonds, Gary O.

    1994-01-01

    The use of robotics in situations involving hazardous materials can significantly reduce the risk of human injuries. The Emergency Response Robotics Project, which began in October 1990 at the Jet Propulsion Laboratory, is developing a teleoperated mobile robot allowing HAZMAT (hazardous materials) teams to remotely respond to incidents involving hazardous materials. The current robot, called HAZBOT III, can assist in locating characterizing, identifying, and mitigating hazardous material incidents without risking entry team personnel. The active involvement of the JPL Fire Department HAZMAT team has been vital in developing a robotic system which enables them to perform remote reconnaissance of a HAZMAT incident site. This paper provides a brief review of the history of the project, discusses the current system in detail, and presents other areas in which robotics can be applied removing people from hazardous environments/operations.

  12. Applied antineutrino physics workshop.

    SciTech Connect

    Lund, James C.

    2008-01-01

    This workshop is the fourth one of a series that includes the Neutrino Geophysics Conference at Honolulu, Hawaii, which I attended in 2005. This workshop was organized by the Astro-Particle and Cosmology laboratory in the recently opened Condoret building of the University of Paris. More information, including copies of the presentations, on the workshop is available on the website: www.apc.univ-paris7.fr/AAP2007/. The workshop aims at opening neutrino physics to various fields such that it can be applied in geosciences, nuclear industry (reactor and spent fuel monitoring) and non-proliferation. The workshop was attended by over 60 people from Europe, USA, Asia and Brazil. The meeting was also attended by representatives of the Comprehensive nuclear-Test Ban Treaty (CTBT) and the International Atomic Energy Agency (IAEA). The workshop also included a workshop dinner on board of a river boat sailing the Seine river.

  13. Methods of applied dynamics

    NASA Technical Reports Server (NTRS)

    Rheinfurth, M. H.; Wilson, H. B.

    1991-01-01

    The monograph was prepared to give the practicing engineer a clear understanding of dynamics with special consideration given to the dynamic analysis of aerospace systems. It is conceived to be both a desk-top reference and a refresher for aerospace engineers in government and industry. It could also be used as a supplement to standard texts for in-house training courses on the subject. Beginning with the basic concepts of kinematics and dynamics, the discussion proceeds to treat the dynamics of a system of particles. Both classical and modern formulations of the Lagrange equations, including constraints, are discussed and applied to the dynamic modeling of aerospace structures using the modal synthesis technique.

  14. Applied computational aerodynamics

    SciTech Connect

    Henne, P.A.

    1990-01-01

    The present volume discusses the original development of the panel method, the mapping solutions and singularity distributions of linear potential schemes, the capabilities of full-potential, Euler, and Navier-Stokes schemes, the use of the grid-generation methodology in applied aerodynamics, subsonic airfoil design, inverse airfoil design for transonic applications, the divergent trailing-edge airfoil innovation in CFD, Euler and potential computational results for selected aerodynamic configurations, and the application of CFD to wing high-lift systems. Also discussed are high-lift wing modifications for an advanced-capability EA-6B aircraft, Navier-Stokes methods for internal and integrated propulsion system flow predictions, the use of zonal techniques for analysis of rotor-stator interaction, CFD applications to complex configurations, CFD applications in component aerodynamic design of the V-22, Navier-Stokes computations of a complete F-16, CFD at supersonic/hypersonic speeds, and future CFD developments.

  15. Lessons learned and applied

    PubMed Central

    Hebert, Corey Joseph; Hall, Corey M.; Odoms, La’ Nyia J.

    2012-01-01

    Most vaccines available in the United States (US) have been incorporated into vaccination schedules for infants and young children, age groups particularly at risk of contracting infectious diseases. High universal vaccination coverage is responsible for substantially reducing or nearly eliminating many of the diseases that once killed thousands of children each year in the US. Despite the success of infant vaccinations, periods of low vaccination coverage and the limited immunogenicity and duration of protection of certain vaccines have resulted in sporadic outbreaks, allowing some diseases to spread in communities. These challenges suggest that expanded vaccination coverage to younger infants and adolescents, and more immunogenic vaccines, may be needed in some instances. This review focuses on the importance of infant immunization and explores the successes and challenges of current early childhood vaccination programs and how these lessons may be applied to other invasive diseases, such as meningococcal disease. PMID:22617834

  16. Blue Flag Distributed Wargaming System

    DTIC Science & Technology

    1992-07-01

    provided IBM compatible personal computer with removeable media with an IDS Plus8-8 eight port serial card with E-Systems provided software. A spare...involved in making such enhancements. Lessons learned from BF 92-1 are also discussed insofar as they suggest attributes which might be integrated into...1401-43919 1 x CABLE, FOM- BPP 401-43929-37 , 1 X CABLE, FOM- BPP 1401-43929-38 x1 X CDSU MODEL 4202 1 1 13348 CDSU ,MODEL 4202 t 1 13343 CDSU

  17. Colored Flag by Double Refraction.

    ERIC Educational Resources Information Center

    Reid, Bill

    1994-01-01

    Describes various demonstrations that illustrate double refraction and rotation of the plane of polarization in stressed, transparent plastics, with the consequent production of colored designs. (ZWH)

  18. Flagging Economy Propels Financial Education

    ERIC Educational Resources Information Center

    Manzo, Kathleen Kennedy

    2008-01-01

    On the same day President Bush signed a $150 billion economic-stimulus package in an attempt to head off a recession and offset a crisis in the home-mortgage market, a group of financial experts and educators met a few blocks from the White House to craft a plan for better preparing Americans, young and old, to manage their money. Financial…

  19. All-American Flag Act

    THOMAS, 112th Congress

    Rep. Braley, Bruce L. [D-IA-1

    2011-04-04

    04/08/2011 Referred to the Subcommittee on Technology, Information Policy, Intergovernmental Relations and Procurement Reform . (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  20. All-American Flag Act

    THOMAS, 111th Congress

    Rep. Braley, Bruce L. [D-IA-1

    2009-06-12

    11/15/2010 Received in the Senate and Read twice and referred to the Committee on Homeland Security and Governmental Affairs. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

  1. Applying Evolutionary Anthropology

    PubMed Central

    Gibson, Mhairi A; Lawson, David W

    2015-01-01

    Evolutionary anthropology provides a powerful theoretical framework for understanding how both current environments and legacies of past selection shape human behavioral diversity. This integrative and pluralistic field, combining ethnographic, demographic, and sociological methods, has provided new insights into the ultimate forces and proximate pathways that guide human adaptation and variation. Here, we present the argument that evolutionary anthropological studies of human behavior also hold great, largely untapped, potential to guide the design, implementation, and evaluation of social and public health policy. Focusing on the key anthropological themes of reproduction, production, and distribution we highlight classic and recent research demonstrating the value of an evolutionary perspective to improving human well-being. The challenge now comes in transforming relevance into action and, for that, evolutionary behavioral anthropologists will need to forge deeper connections with other applied social scientists and policy-makers. We are hopeful that these developments are underway and that, with the current tide of enthusiasm for evidence-based approaches to policy, evolutionary anthropology is well positioned to make a strong contribution. PMID:25684561

  2. Applying microfluidics to electrophysiology.

    PubMed

    Eddington, David T

    2007-01-01

    Microfluidics can be integrated with standard electrophysiology techniques to allow new experimental modalities. Specifically, the motivation for the microfluidic brain slice device is discussed including how the device docks to standard perfusion chambers and the technique of passive pumping which is used to deliver boluses of neuromodulators to the brain slice. By simplifying the device design, we are able to achieve a practical solution to the current unmet electrophysiology need of applying multiple neuromodulators across multiple regions of the brain slice. This is achieved by substituting the standard coverglass substrate of the perfusion chamber with a thin microfluidic device bonded to the coverglass substrate. This was then attached to the perfusion chamber and small holes connect the open-well of the perfusion chamber to the microfluidic channels buried within the microfluidic substrate. These microfluidic channels are interfaced with ports drilled into the edge of the perfusion chamber to access and deliver stimulants. This project represents how the field of microfluidics is transitioning away from proof-of concept device demonstrations and into practical solutions for unmet experimental and clinical needs.

  3. Applying evolutionary anthropology.

    PubMed

    Gibson, Mhairi A; Lawson, David W

    2015-01-01

    Evolutionary anthropology provides a powerful theoretical framework for understanding how both current environments and legacies of past selection shape human behavioral diversity. This integrative and pluralistic field, combining ethnographic, demographic, and sociological methods, has provided new insights into the ultimate forces and proximate pathways that guide human adaptation and variation. Here, we present the argument that evolutionary anthropological studies of human behavior also hold great, largely untapped, potential to guide the design, implementation, and evaluation of social and public health policy. Focusing on the key anthropological themes of reproduction, production, and distribution we highlight classic and recent research demonstrating the value of an evolutionary perspective to improving human well-being. The challenge now comes in transforming relevance into action and, for that, evolutionary behavioral anthropologists will need to forge deeper connections with other applied social scientists and policy-makers. We are hopeful that these developments are underway and that, with the current tide of enthusiasm for evidence-based approaches to policy, evolutionary anthropology is well positioned to make a strong contribution.

  4. Dry Matter Production, Photosynthesis of Flag Leaves and Water Use in Winter Wheat Are Affected by Supplemental Irrigation in the Huang-Huai-Hai Plain of China.

    PubMed

    Man, Jianguo; Shi, Yu; Yu, Zhenwen; Zhang, Yongli

    2015-01-01

    Winter wheat is threatened by drought in the Huang-Huai-Hai Plain of China, thus, effective water-saving irrigation practices are urgently required to maintain its high winter wheat production. This study was conducted from 2012 to 2014 to determine how supplemental irrigation (SI) affected soil moisture, photosynthesis, and dry matter (DM) production of winter wheat by measuring the moisture in 0-20 cm (W2), 0-40 cm (W3), and 0-60 cm (W4) soil profiles. Rainfed (W0) and local SI practice (W1, irrigation with 60 mm each at jointing and anthesis) treatments were designed as controls. The irrigation amount for W3 was significantly lower than that for W1 and W4 but higher than that for W2. The soil relative water content (SRWC) in 0-40 cm soil profiles at jointing after SI for W3 was significantly lower than that for W1 and W4 but higher than that for W2. W3 exhibited lower SRWC in 100-140 and 60-140 cm soil profiles at anthesis after SI and at maturity, respectively, but higher root length density in 60-100 cm soil profiles than W1, W2 and W4. Compared with W1, W2 and W4, photosynthetic and transpiration rates and stomatal conductance of flag leaves for W3 were significantly greater during grain filling, particularly at the mid and later stages. The total DM at maturity, DM in grain and leaves, post-anthesis DM accumulation and its contribution to grain and grain filling duration were higher for W3. The 1000-grain weight, grain yield and water use efficiency for W3 were the highest. Therefore, treatment of increasing SRWC in the 0-40 cm soil profiles to 65% and 70% field capacities at jointing and anthesis (W3), respectively, created a suitable soil moisture environment for winter wheat production, which could be considered as a high yield and water-saving treatment in Huang-Huai-Hai Plain, China.

  5. Validation of MODIS cloud mask and multilayer flag using CloudSat-CALIPSO cloud profiles and a cross-reference of their cloud classifications

    NASA Astrophysics Data System (ADS)

    Wang, Tao; Fetzer, Eric J.; Wong, Sun; Kahn, Brian H.; Yue, Qing

    2016-10-01

    Aqua Moderate Resolution Imaging Spectroradiometer (MODIS) Collection 6 cloud observations (MYD06) at 1 km are collocated with daytime CloudSat-Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO) (C-C) cloud vertical structures (2B-CLDCLASS-LIDAR). For 2007-2010, over 267 million C-C cloud profiles are used to (1) validate MODIS cloud mask and cloud multilayer flag and (2) cross-reference between C-C cloud types and MODIS cloud regimes defined by joint histograms of cloud top pressure (CTP) and cloud optical depth (τ). Globally, of total observations, C-C reports 27.1% clear and 72.9% cloudy, whereas MODIS reports 30.0% confidently clear and 58.7% confidently cloudy, with the rest 7.1% as probably clear and 4.2% as probably cloudy. Agreement between MODIS and C-C is 77.8%, with 20.9% showing both clear and 56.9% showing both cloudy. The 9.1% of observations are clear in MODIS but cloudy in C-C, indicating clouds missed by MODIS; 1.8% of observations are cloudy in MODIS but clear in C-C, likely due to aerosol/dust or surface snow layers misidentified by MODIS. C-C reports 47.4/25.5% single-layer/multilayer clouds, while MODIS reports 26.7/14.0%. For C-C single-layer clouds, 90% of tropical MODIS high (CTP < 440 hPa) and optically thin (τ < 3.6) clouds are identified as cirrus and 60% of high and optically thick (τ > 23) clouds are recognized as deep convective in C-C. Approximately 70% of MODIS low-level (CTP > 680 hPa) clouds are classified as stratocumulus in C-C regardless of region and optical thickness. No systematic relationship exists between MODIS middle-level (680 < CTP < 440 hPa) clouds and C-C cloud types, largely due to different definitions adopted.

  6. Dry Matter Production, Photosynthesis of Flag Leaves and Water Use in Winter Wheat Are Affected by Supplemental Irrigation in the Huang-Huai-Hai Plain of China

    PubMed Central

    Man, Jianguo; Shi, Yu; Yu, Zhenwen; Zhang, Yongli

    2015-01-01

    Winter wheat is threatened by drought in the Huang-Huai-Hai Plain of China, thus, effective water-saving irrigation practices are urgently required to maintain its high winter wheat production. This study was conducted from 2012 to 2014 to determine how supplemental irrigation (SI) affected soil moisture, photosynthesis, and dry matter (DM) production of winter wheat by measuring the moisture in 0–20 cm (W2), 0–40 cm (W3), and 0–60 cm (W4) soil profiles. Rainfed (W0) and local SI practice (W1, irrigation with 60 mm each at jointing and anthesis) treatments were designed as controls. The irrigation amount for W3 was significantly lower than that for W1 and W4 but higher than that for W2. The soil relative water content (SRWC) in 0–40 cm soil profiles at jointing after SI for W3 was significantly lower than that for W1 and W4 but higher than that for W2. W3 exhibited lower SRWC in 100–140 and 60–140 cm soil profiles at anthesis after SI and at maturity, respectively, but higher root length density in 60–100 cm soil profiles than W1, W2 and W4. Compared with W1, W2 and W4, photosynthetic and transpiration rates and stomatal conductance of flag leaves for W3 were significantly greater during grain filling, particularly at the mid and later stages. The total DM at maturity, DM in grain and leaves, post-anthesis DM accumulation and its contribution to grain and grain filling duration were higher for W3. The 1000-grain weight, grain yield and water use efficiency for W3 were the highest. Therefore, treatment of increasing SRWC in the 0–40 cm soil profiles to 65% and 70% field capacities at jointing and anthesis (W3), respectively, created a suitable soil moisture environment for winter wheat production, which could be considered as a high yield and water-saving treatment in Huang-Huai-Hai Plain, China. PMID:26335019

  7. Refuge-seeking impairments mirror metabolic recovery following fisheries-related stressors in the Spanish flag snapper (Lutjanus carponotatus) on the Great Barrier Reef.

    PubMed

    Cooke, Steven J; Messmer, Vanessa; Tobin, Andrew J; Pratchett, Morgan S; Clark, Timothy D

    2014-01-01

    Fisheries and marine park management strategies for large predatory reef fish can mean that a large proportion of captured fish are released. Despite being released, these fish may experience high mortality while they traverse the water column to locate suitable refuge to avoid predators, all the while recovering from the stress of capture. The predatory reef fish Spanish flag snapper (Lutjanus carponotatus) is frequently released because of a minimum-size or bag limit or by fishers targeting more desirable species. Using L. carponotatus as a model, we tested whether simulated fishing stress (exercise and air exposure) resulted in impairments in reflexes (e.g., response to stimuli) and the ability to identify and use refuge in a laboratory arena and whether any impairments were associated with blood physiology or metabolic recovery. Control fish were consistently responsive to reflex tests and rapidly located and entered refugia in the arena within seconds. Conversely, treatment fish (exhausted and air exposed) were unresponsive to stimuli, took longer to search for refugia, and were more apprehensive to enter the refuge once it was located. Consequently, treatment fish took more than 70 times longer than control fish to enter the coral refuge (26.12 vs. 0.36 min, respectively). The finding that fish exposed to stress were hesitant to use refugia suggests that there was likely cognitive, visual, and/or physiological impairment. Blood lactate, glucose, and hematocrit measures were perturbed at 15 and 30 min after the stressor, relative to controls. However, measurements of oxygen consumption rate revealed that about 50% of metabolic recovery occurred within 30 min after the stressor, coinciding with apparent cognitive/visual/physiological recovery. Recovering the treatment fish in aerated, flow-through chambers for 30 min before introduction to the behavioral arena restored reflexes, and "recovered" fish behaved more similarly to controls. Therefore, we suggest that

  8. Essays in applied microeconomics

    NASA Astrophysics Data System (ADS)

    Wang, Xiaoting

    In this dissertation I use Microeconomic theory to study firms' behavior. Chapter One introduces the motivations and main findings of this dissertation. Chapter Two studies the issue of information provision through advertisement when markets are segmented and consumers' price information is incomplete. Firms compete in prices and advertising strategies for consumers with transportation costs. High advertising costs contribute to market segmentation. Low advertising costs promote price competition among firms and improves consumer welfare. Chapter Three also investigates market power as a result of consumers' switching costs. A potential entrant can offer a new product bundled with an existing product to compensate consumers for their switching cost. If the primary market is competitive, bundling simply plays the role of price discrimination, and it does not dominate unbundled sales in the process of entry. If the entrant has market power in the primary market, then bundling also plays the role of leveraging market power and it dominates unbundled sales. The market for electric power generation has been opened to competition in recent years. Chapter Four looks at issues involved in the deregulated electricity market. By comparing the performance of the competitive market with the social optimum, we identify the conditions under which market equilibrium generates socially efficient levels of electric power. Chapter Two to Four investigate the strategic behavior among firms. Chapter Five studies the interaction between firms and unemployed workers in a frictional labor market. We set up an asymmetric job auction model, where two types of workers apply for two types of job openings by bidding in auctions and firms hire the applicant offering them the most profits. The job auction model internalizes the determination of the share of surplus from a match, therefore endogenously generates incentives for an efficient division of the matching surplus. Microeconomic

  9. Applied Historical Astronomy

    NASA Astrophysics Data System (ADS)

    Stephenson, F. Richard

    2014-01-01

    F. Richard Stephenson has spent most of his research career -- spanning more than 45 years -- studying various aspects of Applied Historical Astronomy. The aim of this interdisciplinary subject is the application of historical astronomical records to the investigation of problems in modern astronomy and geophysics. Stephenson has almost exclusively concentrated on pre-telescopic records, especially those preserved from ancient and medieval times -- the earliest reliable observations dating from around 700 BC. The records which have mainly interested him are of eclipses (both solar and lunar), supernovae, sunspots and aurorae, and Halley's Comet. The main sources of early astronomical data are fourfold: records from ancient and medieval East Asia (China, together with Korea and Japan); ancient Babylon; ancient and medieval Europe; and the medieval Arab world. A feature of Stephenson's research is the direct consultation of early astronomical texts in their original language -- either working unaided or with the help of colleagues. He has also developed a variety of techniques to help interpret the various observations. Most pre-telescopic observations are very crude by present-day standards. In addition, early motives for skywatching were more often astrological rather than scientific. Despite these drawbacks, ancient and medieval astronomical records have two remarkable advantages over modern data. Firstly, they can enable the investigation of long-term trends (e.g. in the terrestrial rate of rotation), which in the relatively short period covered by telescopic observations are obscured by short-term fluctuations. Secondly, over the lengthy time-scale which they cover, significant numbers of very rare events (such as Galactic supernovae) were reported, which have few -- if any-- counterparts in the telescopic record. In his various researches, Stephenson has mainly focused his attention on two specific topics. These are: (i) long-term changes in the Earth's rate of

  10. Applied large eddy simulation.

    PubMed

    Tucker, Paul G; Lardeau, Sylvain

    2009-07-28

    Large eddy simulation (LES) is now seen more and more as a viable alternative to current industrial practice, usually based on problem-specific Reynolds-averaged Navier-Stokes (RANS) methods. Access to detailed flow physics is attractive to industry, especially in an environment in which computer modelling is bound to play an ever increasing role. However, the improvement in accuracy and flow detail has substantial cost. This has so far prevented wider industrial use of LES. The purpose of the applied LES discussion meeting was to address questions regarding what is achievable and what is not, given the current technology and knowledge, for an industrial practitioner who is interested in using LES. The use of LES was explored in an application-centred context between diverse fields. The general flow-governing equation form was explored along with various LES models. The errors occurring in LES were analysed. Also, the hybridization of RANS and LES was considered. The importance of modelling relative to boundary conditions, problem definition and other more mundane aspects were examined. It was to an extent concluded that for LES to make most rapid industrial impact, pragmatic hybrid use of LES, implicit LES and RANS elements will probably be needed. Added to this further, highly industrial sector model parametrizations will be required with clear thought on the key target design parameter(s). The combination of good numerical modelling expertise, a sound understanding of turbulence, along with artistry, pragmatism and the use of recent developments in computer science should dramatically add impetus to the industrial uptake of LES. In the light of the numerous technical challenges that remain it appears that for some time to come LES will have echoes of the high levels of technical knowledge required for safe use of RANS but with much greater fidelity.

  11. Applicability of an in-House Saponin-Based Extraction Method in Bruker Biotyper Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry System for Identification of Bacterial and Fungal Species in Positively Flagged Blood Cultures.

    PubMed

    Chien, Jung-Yien; Lee, Tai-Fen; Du, Shin-Hei; Teng, Shih-Hua; Liao, Chun-Hsing; Sheng, Wang-Hui; Teng, Lee-Jene; Hsueh, Po-Ren

    2016-01-01

    We used an in-house saponin-based extraction method to evaluate the performance of the Bruker Biotyper matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF/MS) system for the identification of bacteria and fungi in 405 positively flagged blood culture bottles. Results obtained from MALDI-TOF/MS were compared with those obtained using conventional phenotypic identification methods. Of the 405 positively flagged blood culture bottles, 365 showed monomicrobal growth and were correctly identified to the species (72.1%) or genus (89.6%) level using the Bruker Biotyper system. The remaining 40 positively flagged blood culture bottles showed polymicrobial growth. Of them, 82.5% (n = 33) of the isolates were correctly identified to the species level and 92.5% (n = 37) to the genus level using the Bruker Biotyper system. The overall accuracy of identification to the genus level in flagged blood cultures was 89.5% for Gram-positive organisms, 93.5% for Gram-negative pathogens and 71.9% for fungi. Confidence scores were ≥1.500 for 307 (75.8%) bottles, ≥1.700 for 249 (61.5%) bottles and ≥2.000 for 142 (35.1%) bottles. None of the yeast cultures yielded scores ≥1.700. Using an identification-score cutoff of ≥1.500, the MALDI Biotyper correctly identified 99.2% of Gram-positive bacteria, 97.6% of Gram-negative bacteria and 100% of yeast isolates to the genus level and 77.6% of Gram-positive bacteria, 87.1% of Gram-negative bacteria and 100.0% of yeast isolates to the species level. The overall rate of identification using our protocol was 89.9% (364/405) for genus level identification and 73.1% (296/405) for species level identification. Yeast isolates yielded the lowest confidence scores, which compromised the accuracy of identification. Further optimization of the protein extraction procedure in positive blood cultures is needed to improve the rate of identification.

  12. Applicability of an in-House Saponin-Based Extraction Method in Bruker Biotyper Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry System for Identification of Bacterial and Fungal Species in Positively Flagged Blood Cultures

    PubMed Central

    Chien, Jung-Yien; Lee, Tai-Fen; Du, Shin-Hei; Teng, Shih-Hua; Liao, Chun-Hsing; Sheng, Wang-Hui; Teng, Lee-Jene; Hsueh, Po-Ren

    2016-01-01

    We used an in-house saponin-based extraction method to evaluate the performance of the Bruker Biotyper matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF/MS) system for the identification of bacteria and fungi in 405 positively flagged blood culture bottles. Results obtained from MALDI-TOF/MS were compared with those obtained using conventional phenotypic identification methods. Of the 405 positively flagged blood culture bottles, 365 showed monomicrobal growth and were correctly identified to the species (72.1%) or genus (89.6%) level using the Bruker Biotyper system. The remaining 40 positively flagged blood culture bottles showed polymicrobial growth. Of them, 82.5% (n = 33) of the isolates were correctly identified to the species level and 92.5% (n = 37) to the genus level using the Bruker Biotyper system. The overall accuracy of identification to the genus level in flagged blood cultures was 89.5% for Gram-positive organisms, 93.5% for Gram-negative pathogens and 71.9% for fungi. Confidence scores were ≥1.500 for 307 (75.8%) bottles, ≥1.700 for 249 (61.5%) bottles and ≥2.000 for 142 (35.1%) bottles. None of the yeast cultures yielded scores ≥1.700. Using an identification-score cutoff of ≥1.500, the MALDI Biotyper correctly identified 99.2% of Gram-positive bacteria, 97.6% of Gram-negative bacteria and 100% of yeast isolates to the genus level and 77.6% of Gram-positive bacteria, 87.1% of Gram-negative bacteria and 100.0% of yeast isolates to the species level. The overall rate of identification using our protocol was 89.9% (364/405) for genus level identification and 73.1% (296/405) for species level identification. Yeast isolates yielded the lowest confidence scores, which compromised the accuracy of identification. Further optimization of the protein extraction procedure in positive blood cultures is needed to improve the rate of identification. PMID:27695442

  13. Essays in Applied Microeconomics

    NASA Astrophysics Data System (ADS)

    Ge, Qi

    This dissertation consists of three self-contained applied microeconomics essays on topics related to behavioral economics and industrial organization. Chapter 1 studies how sentiment as a result of sports event outcomes affects consumers' tipping behavior in the presence of social norms. I formulate a model of tipping behavior that captures consumer sentiment following a reference-dependent preference framework and empirically test its relevance using the game outcomes of the NBA and the trip and tipping data on New York City taxicabs. While I find that consumers' tipping behavior responds to unexpected wins and losses of their home team, particularly in close game outcomes, I do not find evidence for loss aversion. Coupled with the findings on default tipping, my empirical results on the asymmetric tipping responses suggest that while social norms may dominate loss aversion, affect and surprises can result in freedom on the upside of tipping. Chapter 2 utilizes a novel data source of airline entry and exit announcements and examines how the incumbent airlines adjust quality provisions as a response to their competitors' announcements and the role of timing in such responses. I find no evidence that the incumbents engage in preemptive actions when facing probable entry and exit threats as signaled by the competitors' announcements in either short term or long term. There is, however, evidence supporting their responses to the competitors' realized entry or exit. My empirical findings underscore the role of timing in determining preemptive actions and suggest that previous studies may have overestimated how the incumbent airlines respond to entry threats. Chapter 3, which is collaborated with Benjamin Ho, investigates the habit formation of consumers' thermostat setting behavior, an often implicitly made decision and yet a key determinant of home energy consumption and expenditures. We utilize a high frequency dataset on household thermostat usage and find that

  14. Essays in applied economics

    NASA Astrophysics Data System (ADS)

    Arano, Kathleen

    Three independent studies in applied economics are presented. The first essay looks at the US natural gas industrial sector and estimates welfare effects associated with the changes in natural gas regulatory policy over the past three decades. Using a disequilibrium model suited to the natural gas industry, welfare transfers and deadweight losses are calculated. Results indicate that deregulation policies, beginning with the NGPA of 1978, have caused the industry to become more responsive to market conditions. Over time, regulated prices converge toward the estimated equilibrium prices. As a result of this convergence, deadweight losses associated with regulation are also diminished. The second essay examines the discounted utility model (DU), the standard model used for intertemporal decision-making. Prior empirical studies challenge the descriptive validity of the model. This essay addresses the four main inconsistencies that have been raised: domain dependence, magnitude effects, time effects, and gain/loss asymmetries. These inconsistencies, however, may be the result of the implicit assumption of linear utility and not a failure of the DU model itself. In order to test this hypothesis, data was collected from in-class surveys of economics classes at Mississippi State University. A random effects model for panel data estimation which accounts for individual specific effects was then used to impute discount rates measured in terms of dollars and utility. All four inconsistencies were found to be present when the dollar measures were used. Using utility measures of the discount rate resolved the inconsistencies in some cases. The third essay brings together two perspectives in the study of religion and economics: modeling religious behavior using economic tools and variables, and modeling economic behavior using religious variables. A system of ordered probit equations is developed to simultaneously model religious activities and economic outcomes. Using data

  15. Applied physiology of swimming.

    PubMed

    Lavoie, J M; Montpetit, R R

    1986-01-01

    Scientific research in swimming over the past 10 to 15 years has been oriented toward multiple aspects that relate to applied and basic physiology, metabolism, biochemistry, and endocrinology. This review considers recent findings on: 1) specific physical characteristics of swimmers; 2) the energetics of swimming; 3) the evaluation of aerobic fitness in swimming; and 4) some metabolic and hormonal aspects related to swimmers. Firstly, the age of finalists in Olympic swimming is not much different from that of the participants from other sports. They are taller and heavier than a reference population of the same age. The height bias in swimming may be the reason for lack of success from some Asian and African countries. Experimental data point toward greater leanness, particularly in female swimmers, than was seen 10 years ago. Overall, female swimmers present a range of 14 to 19% body fat whereas males are much lower (5 to 10%). Secondly, the relationship between O2 uptake and crawl swimming velocity (at training and competitive speeds) is thought to be linear. The energy cost varies between strokes with a dichotomy between the 2 symmetrical and the 2 asymmetrical strokes. Energy expenditure in swimming is represented by the sum of the cost of translational motion (drag) and maintenance of horizontal motion (gravity). The cost of the latter decreases as speed increases. Examination of the question of size-associated effects on the cost of swimming using Huxley's allometric equation (Y = axb) shows an almost direct relationship with passive drag. Expressing energy cost in litres of O2/m/kg is proposed as a better index of technical swimming ability than the traditional expression of VO2/distance in L/km. Thirdly, maximal direct conventional techniques used to evaluate maximal oxygen consumption (VO2 max) in swimming include free swimming, tethered swimming, and flume swimming. Despite the individual peculiarities of each method, with similar experimental conditions

  16. The Routledge Applied Linguistics Reader

    ERIC Educational Resources Information Center

    Wei, Li, Ed.

    2011-01-01

    "The Routledge Applied Linguistics Reader" is an essential collection of readings for students of Applied Linguistics. Divided into five sections: Language Teaching and Learning, Second Language Acquisition, Applied Linguistics, Identity and Power and Language Use in Professional Contexts, the "Reader" takes a broad…

  17. The Fleming Applied Projects Program

    ERIC Educational Resources Information Center

    Spasov, Peter

    2004-01-01

    Applied Projects is a program where every technology student engages in an intensive team project full time during the final academic semester. A wide range of enterprises provide the real-world problems that form the basis of student projects. This article describes the program and how Fleming College uses this program for applied research. To…

  18. An Option in Applied Microbiology.

    ERIC Educational Resources Information Center

    Lee, William E., III

    1988-01-01

    Describes a program option for undergraduate chemical engineering students interested in biotechnology. Discusses how this program is deployed at the University of Southern Florida. Lists courses which apply to this program. Discusses the goals of teaching applied microbiology to engineering majors. (CW)

  19. Development of the Applied Baccalaureate

    ERIC Educational Resources Information Center

    Townsend, Barbara K.; Bragg, Debra D.; Ruud, Collin M.

    2009-01-01

    Increasing demands for economic competitiveness and educational effectiveness have led states and institutions to implement new approaches to facilitating baccalaureate completion. This study examined one of these approaches, the applied baccalaureate degree, which is designed to incorporate applied associate course work and degrees once…

  20. Distinctive expression patterns and roles of the miRNA393/TIR1 homolog module in regulating flag leaf inclination and primary and crown root growth in rice (Oryza sativa).

    PubMed

    Bian, Hongwu; Xie, Yakun; Guo, Fu; Han, Ning; Ma, Shengyun; Zeng, Zhanghui; Wang, Junhui; Yang, Yinong; Zhu, Muyuan

    2012-10-01

    • MicroRNA (miRNA)-mediated regulation of auxin signaling components plays a critical role in plant development. miRNA expression and functional diversity contribute to the complexity of regulatory networks of miRNA/target modules. • This study functionally characterizes two members of the rice (Oryza sativa) miR393 family and their target genes, OsTIR1 and OsAFB2 (AUXIN SIGNALING F-BOX), the two closest homologs of Arabidopsis TRANSPORT INHIBITOR RESPONSE 1 (TIR1). • We found that the miR393 family members possess distinctive expression patterns, with miR393a expressed mainly in the crown and lateral root primordia, as well as the coleoptile tip, and miR393b expressed in the shoot apical meristem. Transgenic plants overexpressing miR393a/b displayed a severe phenotype with hallmarks of altered auxin signaling, mainly including enlarged flag leaf inclination and altered primary and crown root growth. Furthermore, OsAFB2- and OsTIR1-suppressed lines exhibited increased inclination of flag leaves at the booting stage, resembling miR393-overexpressing plants. Moreover, yeast two-hybrid and bimolecular fluorescence complementation assays showed that OsTIR1 and OsAFB2 interact with OsIAA1. • Expression diversification of miRNA393 implies the potential role of miRNA regulation during species evolution. The conserved mechanisms of the miR393/target module indicate the fundamental importance of the miR393-mediated regulation of auxin signal transduction in rice.