Factors affecting the appreciation generated through applying human factors/ergonomics (HFE) principles to systems of work.

PubMed

So, R H Y; Lam, S T

2014-01-01

This retrospective study examined the levels of appreciation (applause) given by clients to Human Factors/Ergonomic (HFE) specialists after they have modified the systems of work. Thirteen non-academic projects were chosen because the HFE interventions involved changed the way workers work at their workplaces. Companies involved range from multi-national corporations and military organizations with thousands of employees to small trading companies with less than 10 employees. In 5 cases the HFE recommendations were fully adopted and well appreciated. In 4 they were largely ignored and not appreciated, with partial adoption and some appreciation in the other 4 cases. Three factors that predict appreciation were identified: (i) alignment between the benefits HFE can provide and the project's key performance indices; (ii) awareness of HFE among the client's senior management; and (iii) a team organization appropriate for applying HFE recommendations. Having an HFE specialist on the client's side can greatly increase levels of appreciation, but lack of such a specialist will not affect levels of appreciation. A clear contractual requirement for HFE intervention does not promote appreciation significantly, but its absence can greatly reduce levels of appreciation. These relationships are discussed using the Kano's model of quality. Means to generate greater appreciation of the benefits of HFE are discussed. Copyright © 2013 Elsevier Ltd and The Ergonomics Society. All rights reserved.

Using neuroimaging to understand the cortical mechanisms of auditory selective attention

PubMed Central

Lee, Adrian KC; Larson, Eric; Maddox, Ross K; Shinn-Cunningham, Barbara G

2013-01-01

Over the last four decades, a range of different neuroimaging tools have been used to study human auditory attention, spanning from classic event-related potential studies using electroencephalography to modern multimodal imaging approaches (e.g., combining anatomical information based on magnetic resonance imaging with magneto- and electroencephalography). This review begins by exploring the different strengths and limitations inherent to different neuroimaging methods, and then outlines some common behavioral paradigms that have been adopted to study auditory attention. We argue that in order to design a neuroimaging experiment that produces interpretable, unambiguous results, the experimenter must not only have a deep appreciation of the imaging technique employed, but also a sophisticated understanding of perception and behavior. Only with the proper caveats in mind can one begin to infer how the cortex supports a human in solving the “cocktail party” problem. PMID:23850664

Characters in Arctostaphylos taxonomy

USGS Publications Warehouse

Keeley, Jon E.; Parker, V. Thomas; Vasey, Michael C.

2017-01-01

There is value in understanding the past and how it has affected the present. Science focuses on empirical findings, and we know that our prior experiences and those of our predecessors play important roles in determining how we interpret the present. We learn from accomplishments and foibles of predecessors and appreciate the real life experiences we have gone through. In our studies of the genus Arctostaphylos Adans. we have been struck by the fascinating stories surrounding taxonomists who have played roles in the development of our current understanding of the group. In addition to providing insights, they sometimes provide humor and lessons on the value of competition versus collaboration. We offer this history of the humans that forged the taxonomy behind Arctostaphylos classification in this light.

Lean Forward and Listen: poetry as a mode of understanding in medicine.

PubMed

Andrews, Angela

2015-01-01

Many claims have been made over recent years for the use of poetry (and, more broadly, literature) in the curriculum of medical students. Most often, poetry is put forward as having the potential to humanize medicine by promoting, for example, empathy, ethical sensitivity, and an appreciation for diverging interpretations. While these endpoints are all important, this essay uses the experience of a junior doctor undertaking a degree in creative writing to consider how the poetic way of seeing and thinking differs from clinical thinking, and why that might matter. In particular, the author considers the importance in medicine of the capacity to not know, as well as the possibilities for a deeper understanding of patients offered by thinking in terms of poetic voice.

A hypothesis on the biological origins and social evolution of music and dance

PubMed Central

Wang, Tianyan

2015-01-01

The origins of music and musical emotions is still an enigma, here I propose a comprehensive hypothesis on the origins and evolution of music, dance, and speech from a biological and sociological perspective. I suggest that every pitch interval between neighboring notes in music represents corresponding movement pattern through interpreting the Doppler effect of sound, which not only provides a possible explanation for the transposition invariance of music, but also integrates music and dance into a common form—rhythmic movements. Accordingly, investigating the origins of music poses the question: why do humans appreciate rhythmic movements? I suggest that human appreciation of rhythmic movements and rhythmic events developed from the natural selection of organisms adapting to the internal and external rhythmic environments. The perception and production of, as well as synchronization with external and internal rhythms are so vital for an organism's survival and reproduction, that animals have a rhythm-related reward and emotion (RRRE) system. The RRRE system enables the appreciation of rhythmic movements and events, and is integral to the origination of music, dance and speech. The first type of rewards and emotions (rhythm-related rewards and emotions, RRREs) are evoked by music and dance, and have biological and social functions, which in turn, promote the evolution of music, dance and speech. These functions also evoke a second type of rewards and emotions, which I name society-related rewards and emotions (SRREs). The neural circuits of RRREs and SRREs develop in species formation and personal growth, with congenital and acquired characteristics, respectively, namely music is the combination of nature and culture. This hypothesis provides probable selection pressures and outlines the evolution of music, dance, and speech. The links between the Doppler effect and the RRREs and SRREs can be empirically tested, making the current hypothesis scientifically concrete. PMID:25741232

Copying and Coping Conceptualizations of Language: Counseling and the Ethic of Appreciation for Human Differences

ERIC Educational Resources Information Center

Hansen, James T.

2008-01-01

The author takes the position that the foundational value of the counseling profession is an ethic of appreciation for human differences. The professional tool that is used to actualize this value is language. In this regard, the philosophical distinction between copying and coping conceptualizations of language is overviewed. The author argues…

"Let Me Show You a Trick!": A Toddler's Use of Humor to Explore, Interpret, and Negotiate Her Familial Environment during a Day in the Life

ERIC Educational Resources Information Center

Cameron, E. Leslie; Kennedy, Katherine M.; Cameron, Catherine Ann

2008-01-01

Children employ different types of humor as they explore, interpret, and negotiate their environments. Whereas an appreciation of verbal incongruity has been a hallmark of older preschooler humor (e.g., McGhee, 1989), more recently, other violations of expectations and clowning also have been identified as ubiquitous during the first two years of…

Identity Rights and Sensitive Ethical Questions: The European Convention on Human Rights and the Regulation of Surrogacy Arrangements.

PubMed

Mulligan, Andrea

2018-02-05

Attitudes to surrogacy vary widely across Europe, leading to great variation in the domestic legal regimes of the Member States of the Council of Europe. Confronted with such diverse approaches, the European Court of Human Rights (ECtHR) faces a difficult task in seeking to apply Convention rights in the surrogacy context, which it has tackled in the recent cases of Mennesson v France and Paradiso and Campanelli v Italy. The primary purpose of this article is to propose an argument as to what the Convention requires of the Member States in the field of surrogacy. It is argued that while tensions exist between the leading cases, they may be reconciled by appreciating the importance of the right to identity, a facet of the right to respect for private life. Properly understood, the case law imposes obligations on the Member States as regards the legal status of surrogate-born children in both cross-border and domestic surrogacy. The secondary purpose of this article is to argue that, in the surrogacy context, the concept of identity should be given a richer interpretation which encompasses the child's relationship with genetic, gestational, and intended parents, and therefore that a narrow margin of appreciation must apply to all State interventions concerning the legal status of surrogate-born children. © The Author(s) 2018. Published by Oxford University Press; All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Science Literacy's Neglected Twin: Numeracy

NASA Astrophysics Data System (ADS)

Follette, K.; McCarthy, D.

2014-07-01

Have introductory astronomy courses moved too far toward qualitative science? By itself, qualitative understanding, even deep appreciation, of the scientific endeavor is insufficient to engender scientific literacy. In order to interpret scientific information encountered in daily life and to distinguish it from pseudoscience, our students must also be quantitatively savvy. A scientifically literate citizen should be able to employ arithmetic, interpret numbers in context, read graphs and tables, and confidently incorporate numbers in writing. A gentle quantitative emphasis permeates our introductory astronomy courses to help our students become aware of their numerical deficits and appreciate the value of numerical thinking. This approach not only helps transform students into more well-informed citizens and capable problem solvers but also helps them achieve a deeper understanding of course material. We present data from an educational study that documents the extent of quantitative illiteracy and shows that improvements in attitude and achievement are possible.

Juveniles' Miranda comprehension: Understanding, appreciation, and totality of circumstances factors.

PubMed

Zelle, Heather; Romaine, Christina L Riggs; Goldstein, Naomi E S

2015-06-01

This study examined juvenile justice-involved youths' understanding and appreciation of the Miranda warnings' rights to silence and legal counsel using the Miranda Rights Comprehension Instruments (Goldstein, Zelle, & Grisso, 2012). It also examined the relationships between totality of circumstances factors and understanding and appreciation of rights. Data were collected from 183 youths (140 boys) in pre- and postadjudication facilities in 2 states. Overall, youths demonstrated greater difficulty on measures of appreciation than understanding, with particular deficits in their abilities to comprehend the abstract concept of the right to silence. Results varied slightly by instrument, highlighting the importance of a multimodal assessment of these complex abilities. Examination of totality of circumstances factors identified relationships between some factors (e.g., age, verbal IQ, academic achievement) and Miranda comprehension, but revealed that other factors (e.g., gender, number of previous arrests) were not significantly related to Miranda understanding or appreciation. The findings support a nuanced conceptualization of Miranda rights comprehension that acknowledges the complexity of understanding and appreciating the warnings. Empirical analyses also support the continued use of some totality of circumstances factors and abandonment of others. Findings underscore the necessity of multimodal assessment and interpretation when conducting capacity to waive Miranda rights evaluations. (c) 2015 APA, all rights reserved).

Bernard Lewis: An Appreciation.

ERIC Educational Resources Information Center

Humphreys, R. Stephen

1990-01-01

Discusses the career and publications of Bernard Lewis, a noted scholar in the field of Middle-Eastern studies and Islamic history. Traces the history of Western-based Islamic historiography. Examines Lewis' interpretation of Islamic history, outlining his political and social views. (RW)

Actor-Network Theory and its role in understanding the implementation of information technology developments in healthcare.

PubMed

Cresswell, Kathrin M; Worth, Allison; Sheikh, Aziz

2010-11-01

Actor-Network Theory (ANT) is an increasingly influential, but still deeply contested, approach to understand humans and their interactions with inanimate objects. We argue that health services research, and in particular evaluations of complex IT systems in health service organisations, may benefit from being informed by Actor-Network Theory perspectives. Despite some limitations, an Actor-Network Theory-based approach is conceptually useful in helping to appreciate the complexity of reality (including the complexity of organisations) and the active role of technology in this context. This can prove helpful in understanding how social effects are generated as a result of associations between different actors in a network. Of central importance in this respect is that Actor-Network Theory provides a lens through which to view the role of technology in shaping social processes. Attention to this shaping role can contribute to a more holistic appreciation of the complexity of technology introduction in healthcare settings. It can also prove practically useful in providing a theoretically informed approach to sampling (by drawing on informants that are related to the technology in question) and analysis (by providing a conceptual tool and vocabulary that can form the basis for interpretations). We draw on existing empirical work in this area and our ongoing work investigating the integration of electronic health record systems introduced as part of England's National Programme for Information Technology to illustrate salient points. Actor-Network Theory needs to be used pragmatically with an appreciation of its shortcomings. Our experiences suggest it can be helpful in investigating technology implementations in healthcare settings.

Proteomics of the Lysosome

PubMed Central

Lübke, Torben; Lobel, Peter; Sleat, David

2009-01-01

Defects in lysosomal function have been associated with numerous monogenic human diseases typically classified as lysosomal storage diseases. However, there is increasing evidence that lysosomal proteins are also involved in more widespread human diseases including cancer and Alzheimer disease. Thus, there is a continuing interest in understanding the cellular functions of the lysosome and an emerging approach to this is the identification of its constituent proteins by proteomic analyses. To date, the mammalian lysosome has been shown to contain ~ 60 soluble luminal proteins and ~25 transmembrane proteins. However, recent proteomic studies based upon affinity purification of soluble components or subcellular fractionation to obtain both soluble and membrane components suggest that there may be many more of both classes of protein resident within this organelle than previously appreciated. Discovery of such proteins has important implications for understanding the function and the dynamics of the lysosome but can also lead the way towards the discovery of the genetic basis for human diseases of hitherto unknown etiology. Here, we describe current approaches to lysosomal proteomics and data interpretation and review the new lysosomal proteins that have recently emerged from such studies. PMID:18977398

Linguistic complex networks: Rationale, application, interpretation, and directions. Reply to comments on "Approaching human language with complex networks"

NASA Astrophysics Data System (ADS)

Cong, Jin; Liu, Haitao

2014-12-01

Amid the enthusiasm for real-world networks of the new millennium, the enquiry into linguistic networks is flourishing not only as a productive branch of the new networks science but also as a promising approach to linguistic research. Although the complex network approach constitutes a potential opportunity to make linguistics a science, the world of linguistics seems unprepared to embrace it. For one thing, linguistics has been largely unaffected by quantitative methods. Those who are accustomed to qualitative linguistic methods may find it hard to appreciate the application of quantitative properties of language such as frequency and length, not to mention quantitative properties of language modeled as networks. With this in mind, in our review [1] we restrict ourselves to the basics of complex networks and the new insights into human language with the application of complex networks. For another, while breaking new grounds and posing new challenges for linguistics, the complex network approach to human language as a new tradition of linguistic research is faced with challenges and unsolved issues of its own. It is no surprise that the comments on our review, especially their skepticism and suggestions, focus on various different aspects of the complex network approach to human language. We are grateful to all the insightful and penetrating comments, which, together with our review, mark a significant impetus to linguistic research from the complex network approach. In this reply, we would like to address four major issues of the complex network approach to human language, namely, a) its theoretical rationale, b) its application in linguistic research, c) interpretation of the results, and d) directions of future research.

Video medical interpretation over 3G cellular networks: a feasibility study.

PubMed

Locatis, Craig; Williamson, Deborah; Sterrett, James; Detzler, Isabel; Ackerman, Michael

2011-12-01

To test the feasibility of using cell phone technology to provide video medical interpretation services at a distance. Alternative cell phone services were researched and videoconferencing technologies were tried out to identify video products and telecommunication services needed to meet video medical interpretation requirements. The video and telecommunication technologies were tried out in a pharmacy setting and compared with use of the telephone. Outcomes were similar to findings in previous research involving video medical interpretation with higher bandwidth and video quality. Patients appreciated the interpretation service no matter how it is provided, while health providers and interpreters preferred video. It is possible to provide video medical interpretation services via cellular communication using lower bandwidth videoconferencing technology that provides sufficient quality, at least in pharmacy settings. However, a number of issues need to be addressed to ensure quality of service.

From Darwin to constructivism: the evolution of grounded theory.

PubMed

Hall, Helen; Griffiths, Debra; McKenna, Lisa

2013-01-01

To explore the evolution of grounded theory and equip the reader with a greater understanding of the diverse conceptual positioning that is evident in the methodology. Grounded theory was developed during the modernist phase of research to develop theories that are derived from data and explain human interaction. Its philosophical foundations derive from symbolic interactionism and were influenced by a range of scholars including Charles Darwin and George Mead. Rather than a rigid set of rules and procedures, grounded theory is a way of conceptualising data. Researchers demonstrate a range of perspectives and there is significant variation in the way the methodology is interpreted and executed. Some grounded theorists continue to align closely with the original post-positivist view, while others take a more constructivist approach. Although the diverse interpretations accommodate flexibility, they may also result in confusion. The grounded theory approach enables researchers to align to their own particular world view and use methods that are flexible and practical. With an appreciation of the diverse philosophical approaches to grounded theory, researchers are enabled to use and appraise the methodology more effectively.

Tissue Penetration of Antifungal Agents

PubMed Central

Felton, Timothy; Troke, Peter F.

2014-01-01

SUMMARY Understanding the tissue penetration of systemically administered antifungal agents is critical for a proper appreciation of their antifungal efficacy in animals and humans. Both the time course of an antifungal drug and its absolute concentrations within tissues may differ significantly from those observed in the bloodstream. In addition, tissue concentrations must also be interpreted within the context of the pathogenesis of the various invasive fungal infections, which differ significantly. There are major technical obstacles to the estimation of concentrations of antifungal agents in various tissue subcompartments, yet these agents, even those within the same class, may exhibit markedly different tissue distributions. This review explores these issues and provides a summary of tissue concentrations of 11 currently licensed systemic antifungal agents. It also explores the therapeutic implications of their distribution at various sites of infection. PMID:24396137

Pappas and Tepe's Pathways to Knowledge Model.

ERIC Educational Resources Information Center

Zimmerman, Nancy P.; Pappas, Marjorie L.; Tepe, Ann E.

2002-01-01

Describes the Pathways to Knowledge model for helping students achieve information literacy in library media programs. Discusses the searcher's thinking, information search or seeking, and instructional strategies; information skills; the six stages in the model, including appreciation, presearch, search, interpretation, communication, and…

The medium is the message: thoughts on picture perfect presentation.

PubMed

Jupiter, Daniel C

2013-01-01

Clear presentation of results leads to easier interpretation and appreciation by readers. Opinions and tips are offered to ease clear communication. Copyright © 2013 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.

Fossils, feet and the evolution of human bipedal locomotion

PubMed Central

Harcourt-Smith, W E H; Aiello, L C

2004-01-01

We review the evolution of human bipedal locomotion with a particular emphasis on the evolution of the foot. We begin in the early twentieth century and focus particularly on hypotheses of an ape-like ancestor for humans and human bipedal locomotion put forward by a succession of Gregory, Keith, Morton and Schultz. We give consideration to Morton's (1935) synthesis of foot evolution, in which he argues that the foot of the common ancestor of modern humans and the African apes would be intermediate between the foot of Pan and Hylobates whereas the foot of a hypothetical early hominin would be intermediate between that of a gorilla and a modern human. From this base rooted in comparative anatomy of living primates we trace changing ideas about the evolution of human bipedalism as increasing amounts of postcranial fossil material were discovered. Attention is given to the work of John Napier and John Robinson who were pioneers in the interpretation of Plio-Pleistocene hominin skeletons in the 1960s. This is the period when the wealth of evidence from the southern African australopithecine sites was beginning to be appreciated and Olduvai Gorge was revealing its first evidence for Homo habilis. In more recent years, the discovery of the Laetoli footprint trail, the AL 288-1 (A. afarensis) skeleton, the wealth of postcranial material from Koobi Fora, the Nariokotome Homo ergaster skeleton, Little Foot (Stw 573) from Sterkfontein in South Africa, and more recently tantalizing material assigned to the new and very early taxa Orrorin tugenensis, Ardipithecus ramidus and Sahelanthropus tchadensis has fuelled debate and speculation. The varying interpretations based on this material, together with changing theoretical insights and analytical approaches, is discussed and assessed in the context of new three-dimensional morphometric analyses of australopithecine and Homo foot bones, suggesting that there may have been greater diversity in human bipedalism in the earlier phases of our evolutionary history than previously suspected. PMID:15198703

Panoramic Scanning: Essential Element of Higher-Order Thought.

ERIC Educational Resources Information Center

Ambrose, Don

1996-01-01

Panoramic scanning is the capacity to perceive, interpret, and appreciate complex problems from a big-picture vantage point. Barriers to panoramic scanning (sensory bombardment, superficial polarized thought, and tunnel vision) and facilitators (broad interests and knowledge, pattern finding, and connection-making skills) are identified. Educators…

Identification of cis-suppression of human disease mutations by comparative genomics.

PubMed

Jordan, Daniel M; Frangakis, Stephan G; Golzio, Christelle; Cassa, Christopher A; Kurtzberg, Joanne; Davis, Erica E; Sunyaev, Shamil R; Katsanis, Nicholas

2015-08-13

Patterns of amino acid conservation have served as a tool for understanding protein evolution. The same principles have also found broad application in human genomics, driven by the need to interpret the pathogenic potential of variants in patients. Here we performed a systematic comparative genomics analysis of human disease-causing missense variants. We found that an appreciable fraction of disease-causing alleles are fixed in the genomes of other species, suggesting a role for genomic context. We developed a model of genetic interactions that predicts most of these to be simple pairwise compensations. Functional testing of this model on two known human disease genes revealed discrete cis amino acid residues that, although benign on their own, could rescue the human mutations in vivo. This approach was also applied to ab initio gene discovery to support the identification of a de novo disease driver in BTG2 that is subject to protective cis-modification in more than 50 species. Finally, on the basis of our data and models, we developed a computational tool to predict candidate residues subject to compensation. Taken together, our data highlight the importance of cis-genomic context as a contributor to protein evolution; they provide an insight into the complexity of allele effect on phenotype; and they are likely to assist methods for predicting allele pathogenicity.

Cultural Arts Handbook.

ERIC Educational Resources Information Center

Pistone, Kathleen A.

The handbook presents activities to aid elementary school classroom teachers as they develop and implement cultural arts lessons. A cultural arts program is interpreted as a way to help students develop perceptual awareness, build a basic vocabulary in some art cultural form, evaluate their own works of art, appreciate creative expressions, and…

Geoheritage, geotourism and cultural landscapes in Scotland

NASA Astrophysics Data System (ADS)

Gordon, John E.

2015-04-01

Geoheritage is closely linked with many aspects of cultural heritage and the development of tourism in Scotland. Historically, aesthetic appreciation of the physical landscape and links with literature and art formed the foundation for tourism during the 18th and 19th centuries. Today, exploration of the cultural links between geodiversity and landscape is providing new opportunities for raising awareness of geoheritage through literature, poetry, art and the built heritage. Interpreting the cultural dimension of geodiversity can enable people to connect with geodiversity through different experiences and a renewed sense of wonder about the physical landscape and the creative inspiration provided by geodiversity. It can also link geodiversity to cultural roots and sense of place, allowing exploration of different connections between people and the natural world. Such experiential engagement is promoted through the development of Geoparks. It requires thinking about how interpretation can add value to people's experiences and provide involvement that evokes a sense of wonder about the physical landscape. This means encouraging new and memorable experiential ways of interpreting the landscape and communicating its geological stories, not simply presenting information. Rediscovering a sense of wonder about the physical landscape through cultural links can enable wider public appreciation of geoheritage and help to develop greater support for geoconservation.

Parallel overinterpretation of behavior of apes and corvids.

PubMed

Hampton, Robert

2018-06-20

The report by Kabadayi and Osvath (Science, 357(6347), 202-204, 2017) does not demonstrate planning in ravens. The behavior of corvids and apes is fascinating and will be best appreciated through well-designed experiments that explicitly test alternative explanations and that are interpreted without unjustified anthropomorphic embellishment.

Teaching and Learning Research Literacies in Graduate Adult Education: Appreciative Inquiry into Practitioners' Ways of Writing.

ERIC Educational Resources Information Center

Lander, Dorothy A.

2002-01-01

Presents a theoretical framework for teaching and learning research literacies. Describes a classroom demonstration involving graduate student cohorts in appreciative inquiry into practitioners' ways of writing. Addresses the issues of human subjects, informed consent, and the ethics of representation. (Contains 49 references.) (SK)

Appreciative Inquiry. Trends and Issues Alert.

ERIC Educational Resources Information Center

Kerka, Sandra

Appreciative inquiry (AI) is based on the heliotropic principle, which has been variously described as art and science, holistic theory and practice, and practical philosophy and change process. AI engages people and organizations in discovering what gives life to human systems when they are most effective and constructive and using that knowledge…

Teaching Techniques: Physical Vocabulary in the Beginner-Level Classroom

ERIC Educational Resources Information Center

Maiullo, Jonathan

2016-01-01

After having success with this warm-up activity in his theater classes, the author adapted it for his beginner-level English classes, knowing his students would appreciate the opportunity to move around. The activity allows students to create their own physical interpretation of a vocabulary word, which increases their ability to remember it…

Teaching and Learning about Epistemic Insight

ERIC Educational Resources Information Center

Billingsley, Berry

2017-01-01

Epistemic Insight is a research and education initiative that is seeking to establish effective ways to help school students to appreciate the power and limitations of science. In particular, the idea is that experiences and explanations devised by a teacher who is focused on what happens inside the science classroom might not be interpreted as…

Beyond Slopes and Points: Teaching Students How Graphs Describe the Relationships between Scientific Pheomena

ERIC Educational Resources Information Center

Harris, David; Gomez Zwiep, Susan

2013-01-01

Graphs represent complex information. They show relationships and help students see patterns and compare data. Students often do not appreciate the illuminating power of graphs, interpreting them literally rather than as symbolic representations (Leinhardt, Zaslavsky, and Stein 1990). Students often read graphs point by point instead of seeing…

EFL Students' Perceptions of Social Issues in Famous Works of Art

ERIC Educational Resources Information Center

Bautista Urrego, Lizmendy Zuhey; Parra Toro, Ingrid Judith

2016-01-01

This article reports on a qualitative, descriptive, and interpretative research intervention case study of English as a foreign language students' construction of perceptions on social issues found in famous works of art. Participants in this study engaged in the practice of critical thinking as a strategy to appreciate art that expresses social…

Goals, Purposes, and Future of Undergraduate Education in the Psychology of Aging

ERIC Educational Resources Information Center

Schonfield, David; Chatfield, Sally

1976-01-01

An introductory course in gerontology should be tied to the liberal arts core of higher education and not merely provide assembly lines of facts. Undergraduates should be helped to appreciate difficulties in designing and interpreting gerontological studies and to realize that they are not yet ready to undertake independent empirical…

Primary Students' Understanding and Appreciation of the Artwork in Picturebooks

ERIC Educational Resources Information Center

Pantaleo, Sylvia

2016-01-01

One of the purposes of the classroom-based research featured in this article was to explore how the ongoing development of young children's understanding of elements of visual art and design would affect their comprehension, interpretation and analysis of the artwork in a selection of picturebooks. Social semiotics, multimodality, sociocultural…

75 FR 17823 - Notice-Interpretation of 49 CFR 158.45

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-07

... communications that the Department and the FAA have provided in prior instances. In the majority of airline... in ``trust'' for the beneficial interest of the eligible agency imposing the fee, and neither the... CFR Sections 158.45 and 158.49. We appreciate the importance of your work on Aloha's behalf, and we...

Don't fight the site: three geomorphic considerations in catchment-scale river rehabilitation planning.

PubMed

Brierley, Gary; Fryirs, Kirstie

2009-06-01

Three geomorphic considerations that underpin the design and implementation of realistic and strategic river conservation and rehabilitation programs that work with the nature are outlined. First, the importance of appreciating the inherent diversity of river forms and processes is discussed. Second, river dynamics are appraised, framing the contemporary behavioral regime of a reach in relation to system evolution to explain changes to river character and behavior over time. Third, the trajectory of a reach is framed in relation to downstream patterns of river types, analyzing landscape connectivity at the catchment scale to interpret geomorphic river recovery potential. The application of these principles is demonstrated using extensive catchment-scale analyses of geomorphic river responses to human disturbance in the Bega and Upper Hunter catchments in southeastern Australia. Differing implications for reach- and catchment-scale rehabilitation planning prompt the imperative that management practices work with nature rather than strive to 'fight the site.'

Self-compassion moderates body comparison and appearance self-worth's inverse relationships with body appreciation.

PubMed

Homan, Kristin J; Tylka, Tracy L

2015-09-01

Although research on positive body image has increased, little research has explored which variables protect body appreciation during body-related threats. Self-compassion may be one such variable. Individuals high in self-compassion are mindful, kind, and nurturing toward themselves during situations that threaten their adequacy, while recognizing that being imperfect is part of "being human." In this study, we investigated whether two body-related threats (i.e., body comparison and appearance contingent self-worth) were more weakly related to body appreciation when self-compassion was high among an online sample of 263 women (Mage=35.26, SD=12.42). Results indicated that self-compassion moderated the inverse relationships between body related threats and body appreciation. Specifically, when self-compassion was very high, body comparison and appearance contingent self-worth were unrelated to body appreciation. However, when self-compassion was low, these relationships were strong. Self-compassion, then, may help preserve women's body appreciation during body-related threats. Copyright © 2015 Elsevier Ltd. All rights reserved.

Identification of cis-suppression of human disease mutations by comparative genomics

PubMed Central

Jordan, Daniel M.; Frangakis, Stephan G.; Golzio, Christelle; Cassa, Christopher A.; Kurtzberg, Joanne; Davis, Erica E.; Sunyaev, Shamil R.; Katsanis, Nicholas

2015-01-01

Patterns of amino acid conservation have served as a tool for understanding protein evolution1. The same principles have also found broad application in human genomics, driven by the need to interpret the pathogenic potential of variants in patients2. Here we performed a systematic comparative genomics analysis of human disease-causing missense variants. We found that an appreciable fraction of disease-causing alleles are fixed in the genomes of other species, suggesting a role for genomic context. We developed a model of genetic interactions that predicts most of these to be simple pairwise compensations. Functional testing of this model on two known human disease genes3,4 revealed discrete cis amino acid residues that, although benign on their own, could rescue the human mutations in vivo. This approach was also applied to ab initio gene discovery to support the identification of a de novo disease driver in BTG2 that is subject to protective cis-modification in more than 50 species. Finally, on the basis of our data and models, we developed a computational tool to predict candidate residues subject to compensation. Taken together, our data highlight the importance of cis-genomic context as a contributor to protein evolution; they provide an insight into the complexity of allele effect on phenotype; and they are likely to assist methods for predicting allele pathogenicity5,6. PMID:26123021

Playing to Your Strengths: Appreciative Inquiry in the Visioning Process

ERIC Educational Resources Information Center

Fifolt, Matthew; Stowe, Angela M.

2011-01-01

"Appreciative Inquiry" (AI) is a structured approach to visioning focused on reflection, introspection, and collaboration. Rooted in organizational behavior theory, AI was introduced in the early 1980s as a life-centric approach to human systems (Watkins and Mohr 2001). Since then, AI has been used widely within the business community;…

Socio-cultural Input Facilitates Children’s Developing Understanding of Extraordinary Minds

PubMed Central

Lane, Jonathan D.; Wellman, Henry M.; Evans, E. Margaret

2012-01-01

Three- to 5-year-old (N=61) religiously-schooled preschoolers received theory-of-mind tasks about the mental states of ordinary humans and agents with exceptional perceptual or mental capacities. Consistent with an anthropomorphism hypothesis, children beginning to appreciate limitations of human minds (e.g., ignorance) attributed those limits to God. Only 5-year-olds differentiated between humans’ fallible minds and God’s less fallible mind. Unlike secularly-schooled children, religiously-schooled 4-year-olds did appreciate another agent’s less fallible mental abilities when instructed and reminded about those abilities. Among children who understood ordinary humans’ mental fallibilities, knowledge of God predicted attributions of correct epistemic states to extraordinary agents. Results suggest that, at a certain point in theory-of-mind development, socio-cultural input can facilitate an appreciation for extraordinary minds. PMID:22372590

The Ecology of Parasite-Host Interactions at Montezuma Well National Monument, Arizona - Appreciating the Importance of Parasites

USGS Publications Warehouse

O'Brien, Chris; van Riper, Charles

2009-01-01

Although parasites play important ecological roles through the direct interactions they have with their hosts, historically that fact has been underappreciated. Today, scientists have a growing appreciation of the scope of such impacts. Parasites have been reported to dominate food webs, alter predator-prey relationships, act as ecosystem engineers, and alter community structure. In spite of this growing awareness in the scientific community, parasites are still often neglected in the consideration of the management and conservation of resources and ecosystems. Given that at least half of the organisms on earth are probably parasitic, it should be evident that the ecological functions of parasites warrant greater attention. In this report, we explore different aspects of parasite-host relationships found at a desert spring pond within Montezuma Well National Monument, Arizona. In three separate but related chapters, we explore interactions between a novel amphipod host and two parasites. First, we identify how host behavior responds to this association and how this association affects interactions with both invertebrate non-host predators and a vertebrate host predator. Second, we look at the human dimension, investigating how human recreation can indirectly affect patterns of disease by altering patterns of vertebrate host space use. Finally - because parasites and diseases are of increasing importance in the management of wildlife species, especially those that are imperiled or of management concern - the third chapter argues that research would benefit from increased attention to the statistical analysis of wildlife disease studies. This report also explores issues of statistical parasitology, providing information that may better inform those designing research projects and analyzing data from studies of wildlife disease. In investigating the nature of parasite-host interactions, the role that relationships play in ecological communities, and how human activities alter these associations, scientists usually make inferences by methods of statistical hypotheses testing. This type of hypothesis testing places additional importance on the analysis and interpretation of parasite-host interactions. We address these ideas in this report, focusing on the following questions: (1) How do two parasites with complex life cycles alter the behavior of a novel amphipod host, and how do host and non-host predators respond to infected amphipod prey? (2) Does human recreation affect spatial patterns of infection in an otherwise natural ecosystem? (3) How is hypothesis-testing applied in studies of wildlife disease? (4) What conclusions can we make about the relative usefulness of these methodologies? and (5) How can the analysis and interpretation of wildlife disease studies be improved? Each chapter of this report contains its own literature-cited section, with tables included in appendixes at the end of the full report.

Neural correlates of humor detection and appreciation.

PubMed

Moran, Joseph M; Wig, Gagan S; Adams, Reginald B; Janata, Petr; Kelley, William M

2004-03-01

Humor is a uniquely human quality whose neural substrates remain enigmatic. The present report combined dynamic, real-life content and event-related functional magnetic resonance imaging (fMRI) to dissociate humor detection ("getting the joke") from humor appreciation (the affective experience of mirth). During scanning, subjects viewed full-length episodes of the television sitcoms Seinfeld or The Simpsons. Brain activity time-locked to humor detection moments revealed increases in left inferior frontal and posterior temporal cortices, whereas brain activity time-locked to moments of humor appreciation revealed increases in bilateral regions of insular cortex and the amygdala. These findings provide evidence that humor depends critically upon extant neural systems important for resolving incongruities (humor detection) and for the expression of affect (humor appreciation).

Where Does It Come From? Developmental Aspects of Art Appreciation

ERIC Educational Resources Information Center

Schabmann, Alfred; Gerger, Gernot; Schmidt, Barbara M.; Wögerer, Eva; Osipov, Igor; Leder, Helmut

2016-01-01

Art is a unique feature of human experience. It involves the complex interplay among stimuli, persons and contexts. Little is known of how the various features deemed important in art appreciation depend on development, thus are already present at a young age. Similarly to our previous approach with adults of differing levels of expertise, the…

Putting the Mind in the Brain: Promoting an Appreciation of the Biological Basis to Understanding Human Behavior

ERIC Educational Resources Information Center

Neumann, David L.

2010-01-01

A surprising number of students in psychology, behavioral science, and related social science classes fail to appreciate the importance of biological mechanisms to understanding behavior. To help teachers promote this understanding, this paper outlines six sources of evidence. These are (a) phylogenetic, (b) genetic/developmental, (c) clinical,…

The Ghost Forests of Cascadia: How Valuing Geological Inquiry Puts Practice into Place

ERIC Educational Resources Information Center

Ault, Charles R., Jr.

2014-01-01

Interpreting the hazards and appreciating the privileges of living in a particular place draw upon insights from multiple disciplines. Seemingly self-evident, this perspective stands as a counterpoint to the depiction of scientific practice as unified and independent of discipline in standards for the education of all Americans. Inquiry adapts in…

Considerations for interpreting probabilistic estimates of uncertainty of forest carbon

Treesearch

James E. Smith; Linda S. Heath

2000-01-01

Quantitative estimated of carbon inventories are needed as part of nationwide attempts to reduce net release of greenhouse gases and the associated climate forcing. Naturally, an appreciable amount of uncertainty is inherent in such large-scale assessments, especially since both science and policy issues are still evolving. Decision makers need an idea of the...

Lessons Learned from Professional Development Workshops on Using GIS to Teach Geography and History in the K-12 Classroom

ERIC Educational Resources Information Center

Tabor, Lisa K.; Harrington, John A., Jr.

2014-01-01

The brain perceives, recognizes, interprets, comprehends, appreciates, and remembers experiences that are both text and non-text or verbal and nonverbal. This article discusses Dual- encoding as a proven method of teaching that increases student learning retention and incorporates multiple learning styles. Students learn both subjects better when…

Using LANDSAT imagery as a basis for the understanding of the physiographic regions of the United States

NASA Technical Reports Server (NTRS)

Blair, R. W., Jr.

1981-01-01

An undergraduate level course in regional geology is described in which map exercises using LANDSAT composite images are required. From these exercises, students lean to appreciate LANDSAT imagery, learn elementary skills in imagery reading and interpretation, in addition to making the association of geography, geology, maps, and imagery.

Meaning-Making with Colour in Multimodal Texts: An 11-Year-Old Student's Purposeful "Doing"

ERIC Educational Resources Information Center

Pantaleo, Sylvia

2012-01-01

Colour, a visual element of art and design, is a semiotic mode that is used strategically by sign-makers to communicate meaning. Understanding the meaning-making potential of colour can enhance students' understanding, appreciation, interpretation and composition of multimodal texts. This article features a case study of Anya, an 11-year-old…

The artistic design stance and the interpretation of Paleolithic art.

PubMed

De Smedt, Johan; De Cruz, Helen

2013-04-01

The artistic design stance is an important part of art appreciation, but it remains unclear how it can be applied to artworks for which art historical context is no longer available, such as Ice Age art. We propose that some of the designer's intentions can be gathered noninferentially through direct experience with prehistoric artworks.

Understanding "The Old Man and the Sea": A Student Casebook to Issues, Sources, and Historical Documents.

ERIC Educational Resources Information Center

Valenti, Patricia Dunlavy

"The Old Man and the Sea" remains one of Ernest Hemingway's most beloved works. This casebook helps readers interpret and appreciate the thematic concerns of the novel, as well as the contextual issues it explores. Topic chapters provide information on Cuba, including its natural geography, sociopolitical history, and the ethnic…

Mothers' appreciation of chromosomal microarray analysis for autism spectrum disorder.

PubMed

Giarelli, Ellen; Reiff, Marian

2015-10-01

The aim of this study was to examine mothers' experiences with chromosomal microarray analysis (CMA) for a child with autism spectrum disorder (ASD). This is a descriptive qualitative study using thematic content analysis of in-depth interview with 48 mothers of children who had genetic testing for ASD. The principal theme, "something is missing," included missing knowledge about genetics, information on use of the results, explanations of the relevance to the diagnosis, and relevance to life-long care. Two subordinate themes were (a) disappreciation of the helpfulness of scientific information to explain the diagnosis, and (b) returning to personal experience for interpretation. The test "appreciated" in value when results could be linked to the phenotype. © 2015, Wiley Periodicals, Inc.

Body parts and the market place: insights from Thomistic philosophy.

PubMed

Cherry, M J

2000-08-01

With rare exceptions, Roman Catholic moral theologians condemn the sale of human organs for transplantation. Yet, such criticism, while rhetorically powerful, often oversimplifies complex issues. Arguments for the prohibition of a market in human organs may, therefore, depend on a single premise, or a cluster of dubious and allied premises, which when examined cannot hold. In what follows, I will examine the ways in which such arguments are configured. For example, Thomas Aquinas' (1224-1274) understandings of embodiment and moral uses of the body are usually interpreted as, and cited in support of, foreclosing a market in human organs. Aquinas' principle of totality requires that one preserve the wholeness of the human body. In approaching Aquinas' texts, I will assume the role of a revisionist who takes seriously his core commitments, while at the same time indicating that one can further develop his understanding of the body in ways which are supportive of the sale of human organs while remaining in conformity with the author's core concerns. Such considerations will provide significant grounds for concluding that a market in human organs for transplantation appreciates the embodied nature of the human person, respects the body and its parts as personal, rather than as mere things, is consistent with acknowledging God's dominion over our lives and bodies, and constitutes an appropriate utilization of God's gifts to us. Moreover, such a market would likely create significant opportunities charitably to help others, to enhance human dignity and to protect against the serious dehumanization of current national bureaucratic procedures for organ donation.

Hematopoietic stem cells: can old cells learn new tricks?

PubMed

Ho, Anthony D; Punzel, Michael

2003-05-01

Since the establishment of cell lines derived from human embryonic stem (ES) cells, it has been speculated that out of such "raw material," we could some day produce all sorts of replacement parts for the human body. Human pluripotent stem cells can be isolated from embryonic, fetal, or adult tissues. Enormous self-renewal capacity and developmental potential are the characteristics of ES cells. Somatic stem cells, especially those derived from hematopoietic tissues, have also been reported to exhibit developmental potential heretofore not considered possible. The initial evidences for the plasticity potential of somatic stem cells were so encouraging that the opponents of ES cell research used them as arguments for restricting ES cell research. In the past months, however, critical issues have been raised challenging the validity and the interpretation of the initial data. Whereas hematopoietic stem-cell therapy has been a clinical reality for almost 40 years, there is still a long way to go in basic research before novel therapy strategies with stem cells as replacement for other organ systems can be established. Given the present status, we should keep all options open for research in ES cells and adult stem cells to appreciate the complexity of their differentiation pathways and the relative merits of various types of stem cells for regenerative medicine.

Unique geologic insights from "non-unique" gravity and magnetic interpretation

USGS Publications Warehouse

Saltus, R.W.; Blakely, R.J.

2011-01-01

Interpretation of gravity and magnetic anomalies is mathematically non-unique because multiple theoretical solutions are always possible. The rigorous mathematical label of "nonuniqueness" can lead to the erroneous impression that no single interpretation is better in a geologic sense than any other. The purpose of this article is to present a practical perspective on the theoretical non-uniqueness of potential-field interpretation in geology. There are multiple ways to approach and constrain potential-field studies to produce significant, robust, and definitive results. The "non-uniqueness" of potential-field studies is closely related to the more general topic of scientific uncertainty in the Earth sciences and beyond. Nearly all results in the Earth sciences are subject to significant uncertainty because problems are generally addressed with incomplete and imprecise data. The increasing need to combine results from multiple disciplines into integrated solutions in order to address complex global issues requires special attention to the appreciation and communication of uncertainty in geologic interpretation.

On the design of computer-based models for integrated environmental science.

PubMed

McIntosh, Brian S; Jeffrey, Paul; Lemon, Mark; Winder, Nick

2005-06-01

The current research agenda in environmental science is dominated by calls to integrate science and policy to better understand and manage links between social (human) and natural (nonhuman) processes. Freshwater resource management is one area where such calls can be heard. Designing computer-based models for integrated environmental science poses special challenges to the research community. At present it is not clear whether such tools, or their outputs, receive much practical policy or planning application. It is argued that this is a result of (1) a lack of appreciation within the research modeling community of the characteristics of different decision-making processes including policy, planning, and (2) participation, (3) a lack of appreciation of the characteristics of different decision-making contexts, (4) the technical difficulties in implementing the necessary support tool functionality, and (5) the socio-technical demands of designing tools to be of practical use. This article presents a critical synthesis of ideas from each of these areas and interprets them in terms of design requirements for computer-based models being developed to provide scientific information support for policy and planning. Illustrative examples are given from the field of freshwater resources management. Although computer-based diagramming and modeling tools can facilitate processes of dialogue, they lack adequate simulation capabilities. Component-based models and modeling frameworks provide such functionality and may be suited to supporting problematic or messy decision contexts. However, significant technical (implementation) and socio-technical (use) challenges need to be addressed before such ambition can be realized.

Developing an Ethical School through Appreciating Practice? Students' Lived Experience of Ethical Situations in School

ERIC Educational Resources Information Center

Bergmark, Ulrika; Alerby, Eva

2008-01-01

In meetings between people in school our values are shown through, for example, our actions, our speech and body language. These meetings can be regarded as ethical situations, which can arouse strong emotional reactions that ordinary, everyday situations usually do not do. The aim of this paper is to illuminate, interpret and discuss students'…

The Use of History of Science as a Cultural Tool to Promote Students' Empathy with the Culture of Science

ERIC Educational Resources Information Center

Guney, Burcu G.; Seker, Hayati

2012-01-01

It is difficult for students to understand historical settings, connect to today's world, interpret and appreciate scientists' efforts within current perspectives. Empathizing with historical characters and events can mediate understanding nature of physics for students. The purpose of this study was to investigate the effect of history of science…

Pay It Forward: Teacher Candidates' Use of Historical Artifacts to Invigorate K-12 History Instruction

ERIC Educational Resources Information Center

Waring, Scott M.; Torrez, Cheryl; Lipscomb, George

2015-01-01

As advocates of engaging students in historical inquiry and of the use of primary sources to aid in this inquiry, we support the claims of numerous student benefits, such as learning to detect bias, appreciating the interpretive nature of historical thinking, and the drawing of conclusions based on judgments about evidence (Fehn & Koeppen,…

How Does Adding an Emphasis on Socioscientific Issues Influence Student Attitudes about Science, Its Relevance, and Their Interpretations of Sustainability?

ERIC Educational Resources Information Center

Pelch, Michael A.; McConnell, David A.

2017-01-01

A general consensus exists among the leaders of both developed and developing nations that their citizens should be scientifically literate. Therefore, it is important for educational systems to provide students with access to pertinent scientific knowledge, an appreciation for the scientific processes, and the ability to evaluate scientific…

When Five Words Are Not Enough: A Conceptual and Terminological Discussion of English as a Lingua Franca

ERIC Educational Resources Information Center

Friedrich, Patricia; Matsuda, Aya

2010-01-01

The goal of this article is to (re)define key terminology in the study of English as a lingua franca (ELF). Although the diverse perspectives and ideological standpoints represented in competing definitions of terms is appreciated, a critical conversation on definition and interpretation of ELF and other related concepts is crucial in providing a…

Combat Literacy: Creating a Command Climate With Greater Appreciation for the Operational Role of Foreign Language

DTIC Science & Technology

2009-10-23

language and culture of the battle space is critical to effective operational design. Analysis of steps taken by the U.S. military to provide the...advocacy. 15. SUBJECT TERMS Foreign Language, Culture , Linguists, Interpreters, Translators, Training, Situational Awareness 16. SECURITY...DIRECTION 10 CHANGING THE CULTURE 12 CONCLUSIONS AND RECOMMENDATIONS 16 NOTES 18 BIBLIOGRAPHY

Enabled Masses: Challenge and Trust within Modern Social Networks

DTIC Science & Technology

2013-03-01

maintaining the data needed , and completing and reviewing the collection of information. Send comments regarding this burden estimate or any other aspect of...mobile technology presents a challenge to future operations in terms of increased scrutiny. Senior military leaders need to understand and appreciate...increased scrutiny. Senior military leaders need to understand and appreciate the human processes underlying social networks as well as why this

American Art Appreciation Activities Kit: Ready-To-Use Lessons, Slides, and Projects for Grades 7-12.

ERIC Educational Resources Information Center

Hume, Helen D.

This resource kit, for secondary teachers of art, social studies, and the humanities, presents an art appreciation activities program that spans the visual art history of the United States. The kit is organized into nine chronological sections that follow the history of art in the United States: (1) Native American Art (prehistory to the present);…

Control of the exercise hyperpnoea in humans: a modeling perspective.

PubMed

Ward, S A

2000-09-01

Models of the exercise hyperpnoea have classically incorporated elements of proportional feedback (carotid and medullary chemosensory) and feedforward (central and/or peripheral neurogenic) control. However, the precise details of the control process remain unresolved, reflecting in part both technical and interpretational limitations inherent in isolating putative control mechanisms in the intact human, and also the challenges to linear control theory presented by multiple-input integration, especially with regard to the ventilatory and gas-exchange complexities encountered at work rates which engender a metabolic acidosis. While some combination of neurogenic, chemoreflex and circulatory-coupled processes are likely to contribute to the control, the system appears to evidence considerable redundancy. This, coupled with the lack of appreciable error signals in the mean levels of arterial blood gas tensions and pH over a wide range of work rates, has motivated the formulation of innovative control models that reflect not only spatial interactions but also temporal interactions (i.e. memory). The challenge is to discriminate between robust competing control models that: (a) integrate such processes within plausible physiological equivalents; and (b) account for both the dynamic and steady-state system response over a range of exercise intensities. Such models are not yet available.

Increased Awareness, Increased Appreciation

ERIC Educational Resources Information Center

Nightingale, Barbra

2015-01-01

This article provides a student's viewpoint in response to Larry Andrews' article, "The Humanities Are Dead! Long Live the Humanities!," which addresses and solidifies the notion that, at least from the standpoint of academicians, the humanities are alive and well. The author believes that a broader base of learning, an increased…

The sacred in Mesoamerican materials

NASA Astrophysics Data System (ADS)

Salas, Guillermo; Ramírez, José; Noguez, María

2006-05-01

The materials used in Mesoamerica are the focus for the interpretation of pre-Hispanic society cosmovision with the support of the social system perspective of Bruce Malina and Mircea Eliade's concept of the homo religiosus. Malina's illustration of modern occidental culture and the sacred and profane male behavior propsed by Eliade are used to appreciate the Mesoamerican culture and behavior described in the works of recognized Mexican researchers.

The Broad Spectrum of Human Natural Killer Cell Diversity.

PubMed

Freud, Aharon G; Mundy-Bosse, Bethany L; Yu, Jianhua; Caligiuri, Michael A

2017-11-21

Natural killer (NK) cells provide protection against infectious pathogens and cancer. For decades it has been appreciated that two major NK cell subsets (CD56 bright and CD56 dim ) exist in humans and have distinct anatomical localization patterns, phenotypes, and functions in immunity. In light of this traditional NK cell dichotomy, it is now clear that the spectrum of human NK cell diversity is much broader than originally appreciated as a result of variegated surface receptor, intracellular signaling molecule, and transcription factor expression; tissue-specific imprinting; and foreign antigen exposure. The recent discoveries of tissue-resident NK cell developmental intermediates, non-NK innate lymphoid cells, and the capacity for NK cells to adapt and differentiate into long-lived memory cells has added further complexity to this field. Here we review our current understanding of the breadth and generation of human NK cell diversity. Copyright © 2017 Elsevier Inc. All rights reserved.

75 FR 39450 - Terpene Constituents of the Extract of Chenopodium ambrosioides

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-09

... exposures resulting from exposure to residues from this pesticidal extract. C. Biochemical Pesticide Human... that this active ingredient poses no significant human health risk with regard to food use. a. The...) factors in calculating a dose level that poses no appreciable risk. Health risks to humans, including...

Why physician-assisted suicide perpetuates the idolatory of medicine.

PubMed

Cherry, Mark J

2003-01-01

Adequate response to physician-assisted suicide and euthanasia depends on fundamental philosophical and theological issues, including the character of an appropriate philosophically and theologically anchored anthropology, where the central element of traditional Christian anthropology is that humans are created to worship God. As I will argue, Christian morality and moral epistemology must be nested within and understood through this background Christian anthropology. As a result, I will argue that physician-assisted suicide and euthanasia can only be one-sidedly and inadequately appreciated through rational appeal to central values, such as "human dignity" and "self determination", or through "sola scriptura" biblical interpretation, or individual judgments of conscience. Adequately addressing physician-assisted suicide and euthanasia will depend on a more fundamental spiritual-therapeutic approach. This cluster of moral, epistemological, anthropological, and bioethical claims will be explored by drawing on the texts of St. Basil the Great, St. Maximos the Confessor, and St. Isaac the Syrian. Their reflections on medicine, the human good, and its relationship to worship, spiritual therapy, and God will be used as a basis to indicate a broader philosophical perspective, which will be needed to avoid a one-sided, incomplete approach to the challenges of physician-assisted suicide and euthanasia. Medical morality, I argue, is best understood within categories that transcend the right, the good, the just, and the virtuous; namely, the holy.

Students' Visualization of Metallic Bonding and the Malleability of Metals

NASA Astrophysics Data System (ADS)

Cheng, Maurice M. W.; Gilbert, John K.

2014-05-01

This study investigated the mental representations of metallic bonding and the malleability of metals held by three male students aged 14-15 (Year 10) who were attending a Hong Kong school. One student was selected by their chemistry teacher as representing each of the highest, the medium, and the lowest level of attainment in chemistry in a school that admitted students of average general attainment. The students were interviewed and their understandings probed through their provision of drawings and their interpretation of the diagrams that had been previously used by their teacher. Dual coding theory was used to interpret the relative significance of visual and verbal input and the interaction between the two for their understanding. There was evidence that students relied on verbal recall in providing their initial understandings and showed an appreciation of the nature of the structural components of the electron-sea model of metallic bonding. However, they varied in terms of their appreciation of the electrostatic force which was responsible for the malleability of metals. The study suggests that a clearer understanding of the electrostatic force involved can be attained when students experience visual and verbal representations simultaneously, a conclusion supported by dual coding theory. Principles for good practice in using diagrams in teaching are discussed.

Understanding metaphors and idioms: a single-case neuropsychological study in a person with Down syndrome.

PubMed

Papagno, C; Vallar, G

2001-05-01

The ability of subject F.F., diagnosed with Down syndrome, to appreciate nonliteral (interpreting metaphors and idioms) and literal (vocabulary knowledge, including highly specific and unusual items) aspects of language was investigated. F.F. was impaired in understanding both metaphors and idioms, while her phonological, syntactic and lexical-semantic skills were largely preserved. By contrast, some aspects of F.F.'s executive functions and many visuospatial abilities were defective. The suggestion is made that the interpretation of metaphors and idioms is largely independent of that of literal language, preserved in F.F., and that some executive aspects of working memory and visuospatial and imagery processes may play a role.

Neuroscience Fiction as Eidolá: Social Reflection and Neuroethical Obligations in Depictions of Neuroscience in Film.

PubMed

Wurzman, Rachel; Yaden, David; Giordano, James

2017-04-01

Neuroscience and neurotechnology are increasingly being employed to assess and alter cognition, emotions, and behaviors, and the knowledge and implications of neuroscience have the potential to radically affect, if not redefine, notions of what constitutes humanity, the human condition, and the "self." Such capability renders neuroscience a compelling theme that is becoming ubiquitous in literary and cinematic fiction. Such neuro-SciFi (or "NeuroS/F") may be seen as eidolá: a created likeness that can either accurately-or superficially, in a limited way-represent that which it depicts. Such eidolá assume discursive properties implicitly, as emotionally salient references for responding to cultural events and technological objects reminiscent of fictional portrayal; and explicitly, through characters and plots that consider the influence of neurotechnological advances from various perspectives. We argue that in this way, neuroS/F eidolá serve as allegorical discourse on sociopolitical or cultural phenomena, have power to restructure technological constructs, and thereby alter the trajectory of technological development. This fosters neuroethical responsibility for monitoring neuroS/F eidolá and the sociocultural context from which-and into which-the ideas of eidolá are projected. We propose three approaches to this: evaluating reciprocal effects of imaginary depictions on real-world neurotechnological development; tracking changing sociocultural expectations of neuroscience and its uses; and analyzing the actual process of social interpretation of neuroscience to reveal shifts in heuristics, ideas, and attitudes. Neuroethicists are further obliged to engage with other discourse actors about neuroS/F interpretations to ensure that meanings assigned to neuroscientific advances are well communicated and more fully appreciated.

A comprehensive collection of annotations to interpret sequence variation in human mitochondrial transfer RNAs.

PubMed

Diroma, Maria Angela; Lubisco, Paolo; Attimonelli, Marcella

2016-11-08

The abundance of biological data characterizing the genomics era is contributing to a comprehensive understanding of human mitochondrial genetics. Nevertheless, many aspects are still unclear, specifically about the variability of the 22 human mitochondrial transfer RNA (tRNA) genes and their involvement in diseases. The complex enrichment and isolation of tRNAs in vitro leads to an incomplete knowledge of their post-transcriptional modifications and three-dimensional folding, essential for correct tRNA functioning. An accurate annotation of mitochondrial tRNA variants would be definitely useful and appreciated by mitochondrial researchers and clinicians since the most of bioinformatics tools for variant annotation and prioritization available so far cannot shed light on the functional role of tRNA variations. To this aim, we updated our MToolBox pipeline for mitochondrial DNA analysis of high throughput and Sanger sequencing data by integrating tRNA variant annotations in order to identify and characterize relevant variants not only in protein coding regions, but also in tRNA genes. The annotation step in the pipeline now provides detailed information for variants mapping onto the 22 mitochondrial tRNAs. For each mt-tRNA position along the entire genome, the relative tRNA numbering, tRNA type, cloverleaf secondary domains (loops and stems), mature nucleotide and interactions in the three-dimensional folding were reported. Moreover, pathogenicity predictions for tRNA and rRNA variants were retrieved from the literature and integrated within the annotations provided by MToolBox, both in the stand-alone version and web-based tool at the Mitochondrial Disease Sequence Data Resource (MSeqDR) website. All the information available in the annotation step of MToolBox were exploited to generate custom tracks which can be displayed in the GBrowse instance at MSeqDR website. To the best of our knowledge, specific data regarding mitochondrial variants in tRNA genes were introduced for the first time in a tool for mitochondrial genome analysis, supporting the interpretation of genetic variants in specific genomic contexts.

Multi-level human evolution: ecological patterns in hominin phylogeny.

PubMed

Parravicini, Andrea; Pievani, Telmo

2016-06-20

Evolution is a process that occurs at many different levels, from genes to ecosystems. Genetic variations and ecological pressures are hence two sides of the same coin; but due both to fragmentary evidence and to the influence of a gene-centered and gradualistic approach to evolutionary phenomena, the field of paleoanthropology has been slow to take the role of macro-evolutionary patterns (i.e. ecological and biogeographical at large scale) seriously. However, several very recent findings in paleoanthropology stress both climate instability and ecological disturbance as key factors affecting the highly branching hominin phylogeny, from the earliest hominins to the appearance of cognitively modern humans. Allopatric speciation due to geographic displacement, turnover-pulses of species, adaptive radiation, mosaic evolution of traits in several coeval species, bursts of behavioral innovation, serial dispersals out of Africa, are just some of the macro-evolutionary patterns emerging from the field. The multilevel approach to evolution proposed by paleontologist Niles Eldredge is adopted here as interpretative tool, and has yielded a larger picture of human evolution that integrates different levels of evolutionary change, from local adaptations in limited ecological niches to dispersal phenotypes able to colonize an unprecedented range of ecosystems. Changes in global climate and Earth's surface most greatly affected human evolution. Precisely because it is cognitively hard for us to appreciate the long-term common destiny we share with the whole biosphere, it is particularly valuable to highlight the accumulating evidence that human evolution has been deeply affected by global ecological changes that transformed our African continent of origin.

Appreciative Inquiry as an intervention to change nursing practice in in-patient settings: An integrative review.

PubMed

Watkins, Sarah; Dewar, Belinda; Kennedy, Catriona

2016-08-01

High profile accounts of failures in patient care reflect an urgent need for transformational development in healthcare. Appreciative Inquiry is promoted as an approach to exploring and bringing about change in social systems. Appreciative Inquiry has been used extensively in North American business since the late 1980s. The application of Appreciative Inquiry may have merit in the complex world of human health experiences. To identify, evaluate and synthesise the evidence about the impact of Appreciative Inquiry on changing clinical nursing practice in in-patient settings. An integrative review and narrative synthesis. In-patient settings including paediatrics, maternity and mental health. Nurses of all grades, patients, carers, relatives, other healthcare professionals including allied healthcare staff, management and students. An electronic search of the following electronic databases was performed in January 2015 and updated in July 2015: MEDLINE, EMBASE, Cochrane Library (Cochrane database of systematic reviews), Cumulative Index of Nursing and Allied Health Literature, PsychINFO, PsychARTICLES, Amed, Assia, Scopus and Web of Science. Hand searching of reference lists of included studies was undertaken. Limits were set to include literature published in English only and publications from 1990 to July 2015. Three reviewers independently assessed eligibility for inclusion and extracted data. Full text articles were systematically appraised using a standardised data extraction instrument in conjunction with criteria to assess whether change using Appreciative Inquiry is transformational. Eight studies (reported in 11 papers) met the inclusion criteria. Overall, these studies demonstrate poor application of Appreciative Inquiry criteria in a nursing context. This makes judgement of the impact difficult. One study achieved transformation against agreed criteria for Appreciative Inquiry. Other included studies demonstrated that Appreciative Inquiry is being perceived as a gateway to knowledge translation rather than transformative change in practice. Appreciative Inquiry offers potential for nurse practice development and change but not without cognisance of the pivotal components. If Appreciative Inquiry is to be perceived as a legitimate research endeavour, there must be engagement and attention to rigour. Findings suggest caution is required against the choreography of Appreciative Inquiry where participant experiences are moulded to fit a previously drafted master plan. Further research is needed to explore the role of expert facilitation in securing and sustaining successful outcomes of Appreciative Inquiry. Copyright © 2016 Elsevier Ltd. All rights reserved.

Graphic symbols as "the mind on paper": links between children's interpretive theory of mind and symbol understanding.

PubMed

Myers, Lauren J; Liben, Lynn S

2012-01-01

Children gradually develop interpretive theory of mind (iToM)-the understanding that different people may interpret identical events or stimuli differently. The present study tested whether more advanced iToM underlies children's recognition that map symbols' meanings must be communicated to others when symbols are iconic (resemble their referents). Children (6-9 years; N = 80) made maps using either iconic or abstract symbols. After accounting for age, intelligence, vocabulary, and memory, iToM predicted children's success in communicating symbols' meaning to a naïve map-user when mapping tasks involved iconic (but not abstract) symbols. Findings suggest children's growing appreciation of alternative representations and of the intentional assignment of meaning, and support the contention that ToM progresses beyond mastery of false belief. © 2011 The Authors. Child Development © 2011 Society for Research in Child Development, Inc.

Influence of aesthetic appreciation of wildlife species on attitudes towards their conservation in Kenyan agropastoralist communities.

PubMed

de Pinho, Joana Roque; Grilo, Clara; Boone, Randall B; Galvin, Kathleen A; Snodgrass, Jeffrey G

2014-01-01

The influence of human aesthetic appreciation of animal species on public attitudes towards their conservation and related decision-making has been studied in industrialized countries but remains underexplored in developing countries. Working in three agropastoralist communities around Amboseli National Park, southern Kenya, we investigated the relative strength of human aesthetic appreciation on local attitudes towards the conservation of wildlife species. Using semi-structured interviewing and free listing (n = 191) as part of a mixed methods approach, we first characterized local aesthetic judgments of wildlife species. With a Generalized Linear Mixed Models (GLMM) approach, we then determined the influence of perceiving four species as beautiful on local support for their protection ("rescuing them"), and of perceiving four other species as ugly on support for their removal from the area, while controlling for informant personal and household socioeconomic attributes. Perceiving giraffe, gazelles and eland as beautiful is the strongest variable explaining support for rescuing them. Ugliness is the strongest variable influencing support for the removal of buffalo, hyena, and elephant (but not lion). Both our qualitative and quantitative results suggest that perceptions of ugly species could become more positive through direct exposure to those species. We propose that protected areas in developing countries facilitate visitation by local residents to increase their familiarity with species they rarely see or most frequently see in conflict with human interests. Since valuing a species for its beauty requires seeing it, protected areas in developing countries should connect the people who live around them with the animals they protect. Our results also show that aesthetic appreciation of biodiversity is not restricted to the industrialized world.

Influence of Aesthetic Appreciation of Wildlife Species on Attitudes towards Their Conservation in Kenyan Agropastoralist Communities

PubMed Central

de Pinho, Joana Roque; Grilo, Clara; Boone, Randall B.; Galvin, Kathleen A.; Snodgrass, Jeffrey G.

2014-01-01

The influence of human aesthetic appreciation of animal species on public attitudes towards their conservation and related decision-making has been studied in industrialized countries but remains underexplored in developing countries. Working in three agropastoralist communities around Amboseli National Park, southern Kenya, we investigated the relative strength of human aesthetic appreciation on local attitudes towards the conservation of wildlife species. Using semi-structured interviewing and free listing (n = 191) as part of a mixed methods approach, we first characterized local aesthetic judgments of wildlife species. With a Generalized Linear Mixed Models (GLMM) approach, we then determined the influence of perceiving four species as beautiful on local support for their protection (“rescuing them”), and of perceiving four other species as ugly on support for their removal from the area, while controlling for informant personal and household socioeconomic attributes. Perceiving giraffe, gazelles and eland as beautiful is the strongest variable explaining support for rescuing them. Ugliness is the strongest variable influencing support for the removal of buffalo, hyena, and elephant (but not lion). Both our qualitative and quantitative results suggest that perceptions of ugly species could become more positive through direct exposure to those species. We propose that protected areas in developing countries facilitate visitation by local residents to increase their familiarity with species they rarely see or most frequently see in conflict with human interests. Since valuing a species for its beauty requires seeing it, protected areas in developing countries should connect the people who live around them with the animals they protect. Our results also show that aesthetic appreciation of biodiversity is not restricted to the industrialized world. PMID:24551176

Beauty and the brain: culture, history and individual differences in aesthetic appreciation.

PubMed

Jacobsen, Thomas

2010-02-01

Human aesthetic processing entails the sensation-based evaluation of an entity with respect to concepts like beauty, harmony or well-formedness. Aesthetic appreciation has many determinants ranging from evolutionary, anatomical or physiological constraints to influences of culture, history and individual differences. There are a vast number of dynamically configured neural networks underlying these multifaceted processes of aesthetic appreciation. In the current challenge of successfully bridging art and science, aesthetics and neuroanatomy, the neuro-cognitive psychology of aesthetics can approach this complex topic using a framework that postulates several perspectives, which are not mutually exclusive. In this empirical approach, objective physiological data from event-related brain potentials and functional magnetic resonance imaging are combined with subjective, individual self-reports.

Beauty and the brain: culture, history and individual differences in aesthetic appreciation

PubMed Central

Jacobsen, Thomas

2010-01-01

Human aesthetic processing entails the sensation-based evaluation of an entity with respect to concepts like beauty, harmony or well-formedness. Aesthetic appreciation has many determinants ranging from evolutionary, anatomical or physiological constraints to influences of culture, history and individual differences. There are a vast number of dynamically configured neural networks underlying these multifaceted processes of aesthetic appreciation. In the current challenge of successfully bridging art and science, aesthetics and neuroanatomy, the neuro-cognitive psychology of aesthetics can approach this complex topic using a framework that postulates several perspectives, which are not mutually exclusive. In this empirical approach, objective physiological data from event-related brain potentials and functional magnetic resonance imaging are combined with subjective, individual self-reports. PMID:19929909

Rationality in Human Movement.

PubMed

O'Brien, Megan K; Ahmed, Alaa A

2016-01-01

It long has been appreciated that humans behave irrationally in economic decisions under risk: they fail to objectively consider uncertainty, costs, and rewards and instead exhibit risk-seeking or risk-averse behavior. We hypothesize that poor estimates of motor variability (influenced by motor task) and distorted probability weighting (influenced by relevant emotional processes) contribute to characteristic irrationality in human movement decisions.

The anatomy of the caudal zona incerta in rodents and primates

PubMed Central

Watson, Charles; Lind, Christopher R P; Thomas, Meghan G

2014-01-01

The caudal zona incerta is the target of a recent modification of established procedures for deep brain stimulation (DBS) for Parkinson's disease and tremor. The caudal zona incerta contains a number of neuronal populations that are distinct in terms of their cytoarchitecture, connections, and pattern of immunomarkers and is located at a position where a number of major tracts converge before turning toward their final destination in the forebrain. However, it is not clear which of the anatomical features of the region are related to its value as a target for DBS. This paper has tried to identify features that distinguish the caudal zona incerta of rodents (mouse and rat) and primates (marmoset, rhesus monkey, and human) from the remainder of the zona incerta. We studied cytoarchitecture, anatomical relationships, the pattern of immunomarkers, and gene expression in both of these areas. We found that the caudal zona incerta has a number of histological and gene expression characteristics that distinguish it from the other subdivisions of the zona incerta. Of particular note are the sparse population of GABA neurons and the small but distinctive population of calbindin neurons. We hope that a clearer appreciation of the anatomy of the region will in the end assist the interpretation of cases in which DBS is used in human patients. PMID:24138151

Replacing positivism in medical geography.

PubMed

Bennett, David

2005-06-01

Revisiting debates about philosophical approaches in medical geography suggests that logical positivism may have been prematurely discarded. An analysis of authoritative texts in medical geography and their sources in human geography shows that logical positivism has been conflated with Comtean positivism, science, empiricism, quantification, science politics, scientism and so on, to produce the "standard version" of the all-purpose pejorative "positivism", which it is easy to dismiss as an evil. It is argued that the standard version fails to do justice to logical positivism, being constructed on sources which are at some distance from the logical positivist movement itself. An alternative approach is then developed, an historically and geographically situated interpretation of logical positivism as a deliberately and knowingly constructed oppositional epistemology within an oppressive and anti-scientific culture predicated on idealist intuitionism. Contrasting the standard version with this alternative reading of logical positivism suggests that much may have been lost in human, and thus, medical geography, by throwing out the logical positivist baby with the "positivism" bath water. It is concluded that continuing to unpack the standard version of logical positivism may identify benefits from a more nuanced appreciation of logical positivism, but it is premature to take these to the level of detailed impacts on the kinds of medical geographies that could be done or the ways of doing them.

MOBI: a marine and earth science interpretation and qualification program for out-of-school environment and natural heritage interpreters and other science communicators in Germany

NASA Astrophysics Data System (ADS)

Schneider, S.; Ellger, C.

2017-12-01

As a contribution to Germany's "Science Year 2016*17 - Seas and Oceans", a large science outreach program organized and financed by the National Ministry for Education and Research, GeoUnion, the umbrella organization of Earth science associations and institutions in Germany, has conducted a series of advance level workshops for out-of-school educators and interpreters in Germany. The workshops were organized in co-operation with geoparks, biosphere reserve areas and other environmental management institutions all over Germany. The goal was to convey various perspectives of modern marine sciences to inland venues, linking important present-day marine themes with the presentation of marine phases in the geological history of the host region. The workshops were designed for park rangers, museum educationalists and other science communicators, initiating a broader impact on target groups such as school classes, (geo-)tourists and stakeholder groups. Our approach has been to combine lectures by top-level scientists (on both ocean literacy aspects and regional geology) with discussions and an on-the-spot learning-and-presenting module based on prepared text and visual material. Beyond earth science issues we have integrated economy, ecology, social sciences as well as arts and humanities aspects. One central topic was the role of the world ocean in climate change; other themes highlighted sea level rise, the thermohaline circulation, sea-floor spreading, coral reefs, over-fishing, various marine species and the problem of plastic waste in the ocean. We had anticipated that marine issues are actually very rarely discussed in inland Germany. A structured presentation of ocean literacy elements has proved to be a new range of topical issues from earth and environmental sciences highly appreciated by the participants.

Sociological and Communication-Theoretical Perspectives on the Commercialization of the Sciences

NASA Astrophysics Data System (ADS)

Leydesdorff, Loet

2013-10-01

Both self-organization and organization are important for the further development of the sciences: the two dynamics condition and enable each other. Commercial and public considerations can interact and "interpenetrate" in historical organization; different codes of communication are then "recombined". However, self-organization in the symbolically generalized codes of communication can be expected to operate at the global level. The Triple Helix model allows for both a neo-institutional appreciation in terms of historical networks of university-industry-government relations and a neo-evolutionary interpretation in terms of three functions: (1) novelty production, (2) wealth generation, and (3) political control. Using this model, one can appreciate both subdynamics. The mutual information in three dimensions enables us to measure the trade-off between organization and self-organization as a possible synergy. The question of optimization between commercial and public interests in the different sciences can thus be made empirical.

Nature and place of crime scene management within forensic sciences.

PubMed

Crispino, Frank

2008-03-01

This short paper presents the preliminary results of a recent study aimed at appreciating the relevant parameters required to qualify forensic science as a science through an epistemological analysis. The reader is invited to reflect upon references within a historical and logical framework which assert that forensic science is based upon two fundamental principles (those of Locard and Kirk). The basis of the assertion that forensic science is indeed a science should be appreciated not only on one epistemological criteria (as Popper's falsification raised by the Daubert hearing was), but also on the logical frameworks used by the individuals involved (investigator, expert witness and trier of fact) from the crime scene examination to the final interpretation of the evidence. Hence, it can be argued that the management of the crime scene should be integrated into the scientific way of thinking rather than remain as a technical discipline as recently suggested by Harrison.

Hello Worlds

ERIC Educational Resources Information Center

Kirschenbaum, Matthew

2009-01-01

The author advocates that humanities scholars should seek and study programming languages. He believes that, increasingly, an appreciation of how complex ideas can be imagined and expressed as a set of formal procedures--rules, models, algorithms--in the virtual space of a computer will be an essential element of a humanities education. Students…

A mixed methods study of Canadian adolescents’ perceptions of health

PubMed Central

Pickett, William; Vandemeer, Eleanor; Taylor, Brian; Davison, Colleen

2016-01-01

Health perceptions adopted during childhood lay foundations for adult health trajectories and experiences. This study used a sequential mixed methods design to generate new evidence about child perceptions of health in two samples of Canadian children. A core qualitative study was followed by a complementary quantitative analysis to aid interpretation. Generational theory was used as a lens through which to interpret all data. Findings suggested that good health is perceived as customized and subjective. The strengths and liabilities of these perceptions are discussed, as well as implications for health promotion and prevention strategies. Through intentional consideration of the perspectives of this population group, this study makes both empirical and theoretical contributions to appreciating how cultural environments shape health perceptions. PMID:27741955

The Human Side of 18th-Century French History: Unique Readings for Secondary Students

ERIC Educational Resources Information Center

Roselle, Daniel, Ed.

1976-01-01

Nine short stories and excerpts are presented relating to 18th-Century French History. The purpose of the readings are to: 1) increase student sensitivity to conditions in 18th-Century France; 2) add to their appreciation of the variety of human experiences; and 3) strengthen student insight into the nature of human beings. (Author/JR)

Human and biophysical legacies shape contemporary urban forests: A literature synthesis

Treesearch

Lara A. Roman; Hamil Pearsall; Theodore S. Eisenman; Tenley M. Conway; Robert T. Fahey; Shawn Landry; Jess Vogt; Natalie S. van Doorn; J. Morgan Grove; Dexter H. Locke; Adrina C. Bardekjian; John J. Battles; Mary L. Cadenasso; Cecil C. Konijnendijk van den Bosch; Meghan Avolio; Adam Berland; G. Darrel Jenerette; Sarah K. Mincey; Diane E. Pataki; Christina Staudhammer

2018-01-01

Understanding how urban forests developed their current patterns of tree canopy cover, species composition, and diversity requires an appreciation of historical legacy effects. However, analyses of current urban forest characteristics are often limited to contemporary socioeconomic factors, overlooking the role of history. The institutions, human communities, and...

Ecosystem services: a new NRS-FIA analytical science initiative

Treesearch

Brian G. Tavernia; Mark D. Nelson; James D. Garner

2015-01-01

Forest ecosystem services (ES) are linked to sustaining human well-being. Recognizing an inappropriate economic valuation of ecosystem properties and processes, many ecologists, economists, and political scientists have pushed for an increasing awareness and appreciation of ES. Many definitions of ES include both direct and indirect benefits humans derive from...

Respect-Due and Respect-Earned: Negotiating Student-Teacher Relationships

ERIC Educational Resources Information Center

Goodman, Joan F.

2009-01-01

Respect is a cardinal virtue in schools and foundational to our common ethical beliefs, yet its meaning is muddled. For philosophers Kant, Mill, and Rawls, whose influential theories span three centuries, respect includes appreciation of universal human dignity, equality, and autonomy. In their view children, possessors of human dignity, but…

Stimulating Cultural Appetites: An Experiential Gourmet Approach

ERIC Educational Resources Information Center

Chavez, Carolyn I.; Hu Poirier, Vickie

2007-01-01

This article is an extension of a presentation that won "Best Exercise" at the Eastern Academy of Management, 1998. The authors introduce an experiential gourmet approach using "food stories" to stimulate an aura of acceptance and appreciation for human commonalities before delving into human differences. The authors use a semester long…

Humanities in the High School Classroom.

ERIC Educational Resources Information Center

Stawski, Conrad

A humanities course that teaches an appreciation of tradition and culture through the visual arts includes consideration of contemporary art as well as classic paintings and sculpture. Study of Leonardo DaVinci's "Last Supper" provides an exercise in the intellectual approach to religious painting, while the portrait of Mona Lisa by the same…

Sociocultural Input Facilitates Children's Developing Understanding of Extraordinary Minds

ERIC Educational Resources Information Center

Lane, Jonathan D.; Wellman, Henry M.; Evans, E. Margaret

2012-01-01

Three- to 5-year-old (N = 61) religiously schooled preschoolers received theory-of-mind (ToM) tasks about the mental states of ordinary humans and agents with exceptional perceptual or mental capacities. Consistent with an anthropomorphism hypothesis, children beginning to appreciate limitations of human minds (e.g., ignorance) attributed those…

Xanthine oxido-reductase activity in ischemic human and rat intestine.

PubMed

Bianciardi, Paola; Scorza, Roberto; Ghilardi, Giorgio; Samaja, Michele

2004-09-01

We measured time course and extent of xanthine dehydrogenase (XD) to xanthine oxidase (XO) conversion in ischemic human and rat intestine. To model normothermic no-flow ischemia, we incubated fresh biopsies for 0, 2, 4, 8 and 16h. At t = 0h, XO was less in humans than in rats (P < 0.0004), while XD was essentially the same (P = NS). After 16h incubation at 37 degrees C, there was no appreciable XD-to-XO conversion and no change in neither XO nor XD activity in human intestine. In contrast, the rat intestine had XO/(XO + XD) ratio doubled in the first 2h and then maintained that value until t = 16 h. In conclusion, no XO-to-XD conversion was appreciable after 16 h no-flow normothermic ischemia in human intestine; in contrast, XO activity in rats increased sharply after the onset of ischemia. An immunohistochemical labelling study shows that, whereas XO + XD expression in liver tissue is localised in both hepatocytes and endothelial cells, in the intestine that expression is mostly localised in epithelial cells. We conclude that XO may be considered as a major source of reactive oxygen species in rats but not in humans.

Human attitudes towards herpetofauna: The influence of folklore and negative values on the conservation of amphibians and reptiles in Portugal

PubMed Central

2012-01-01

Background Human values and folklore of wildlife strongly influence the effectiveness of conservation efforts. These values and folklore may also vary with certain demographic characteristics such as gender, age, or education. Reptiles and amphibians are among the least appreciated of vertebrates and are victims of many negative values and wrong ideas resulting from the direct interpretation of folklore. We try to demonstrate how these values and folklore can affect the way people relate to them and also the possible conservation impacts on these animals. Methods A questionnaire survey distributed to 514 people in the district of Évora, Portugal, was used to obtain data regarding the hypothesis that the existence of wrong ideas and negative values contributes to the phenomenon of human-associated persecution of these animals. A structural equation model was specified in order to confirm the hypothesis about the possible relationships between the presence of perceptions and negative values about amphibians and reptiles and persecution and anti-conservation attitudes. Sociodemographic variables were also added. Results The results of the model suggest that the presence of folklore and negative values clearly predicts persecution and anti-conservation attitudes towards amphibians and reptiles. Also, the existence of folklore varies sociodemographically, but negative values concerning these animals are widespread in the population. Conclusions With the use of structural equation models, this work is a contribution to the study of how certain ideas and values can directly influence human attitudes towards herpetofauna and how they can be a serious conservation issue. PMID:22316318

Human attitudes towards herpetofauna: the influence of folklore and negative values on the conservation of amphibians and reptiles in Portugal.

PubMed

Ceríaco, Luis Mp

2012-02-08

Human values and folklore of wildlife strongly influence the effectiveness of conservation efforts. These values and folklore may also vary with certain demographic characteristics such as gender, age, or education. Reptiles and amphibians are among the least appreciated of vertebrates and are victims of many negative values and wrong ideas resulting from the direct interpretation of folklore. We try to demonstrate how these values and folklore can affect the way people relate to them and also the possible conservation impacts on these animals. A questionnaire survey distributed to 514 people in the district of Évora, Portugal, was used to obtain data regarding the hypothesis that the existence of wrong ideas and negative values contributes to the phenomenon of human-associated persecution of these animals. A structural equation model was specified in order to confirm the hypothesis about the possible relationships between the presence of perceptions and negative values about amphibians and reptiles and persecution and anti-conservation attitudes. Sociodemographic variables were also added. The results of the model suggest that the presence of folklore and negative values clearly predicts persecution and anti-conservation attitudes towards amphibians and reptiles. Also, the existence of folklore varies sociodemographically, but negative values concerning these animals are widespread in the population. With the use of structural equation models, this work is a contribution to the study of how certain ideas and values can directly influence human attitudes towards herpetofauna and how they can be a serious conservation issue.

The analyst's participation in the analytic process.

PubMed

Levine, H B

1994-08-01

The analyst's moment-to-moment participation in the analytic process is inevitably and simultaneously determined by at least three sets of considerations. These are: (1) the application of proper analytic technique; (2) the analyst's personally-motivated responses to the patient and/or the analysis; (3) the analyst's use of him or herself to actualise, via fantasy, feeling or action, some aspect of the patient's conflicts, fantasies or internal object relationships. This formulation has relevance to our view of actualisation and enactment in the analytic process and to our understanding of a series of related issues that are fundamental to our theory of technique. These include the dialectical relationships that exist between insight and action, interpretation and suggestion, empathy and countertransference, and abstinence and gratification. In raising these issues, I do not seek to encourage or endorse wild analysis, the attempt to supply patients with 'corrective emotional experiences' or a rationalisation for acting out one's countertransferences. Rather, it is my hope that if we can better appreciate and describe these important dimensions of the analytic encounter, we can be better prepared to recognise, understand and interpret the continual streams of actualisation and enactment that are embedded in the analytic process. A deeper appreciation of the nature of the analyst's participation in the analytic process and the dimensions of the analytic process to which that participation gives rise may offer us a limited, although important, safeguard against analytic impasse.

On the Structural Plasticity of the Human Genome: Chromosomal Inversions Revisited

PubMed Central

Alves, Joao M; Lopes, Alexandra M; Chikhi, Lounès; Amorim, António

2012-01-01

With the aid of novel and powerful molecular biology techniques, recent years have witnessed a dramatic increase in the number of studies reporting the involvement of complex structural variants in several genomic disorders. In fact, with the discovery of Copy Number Variants (CNVs) and other forms of unbalanced structural variation, much attention has been directed to the detection and characterization of such rearrangements, as well as the identification of the mechanisms involved in their formation. However, it has long been appreciated that chromosomes can undergo other forms of structural changes - balanced rearrangements - that do not involve quantitative variation of genetic material. Indeed, a particular subtype of balanced rearrangement – inversions – was recently found to be far more common than had been predicted from traditional cytogenetics. Chromosomal inversions alter the orientation of a specific genomic sequence and, unless involving breaks in coding or regulatory regions (and, disregarding complex trans effects, in their close vicinity), appear to be phenotypically silent. Such a surprising finding, which is difficult to reconcile with the classical interpretation of inversions as a mechanism causing subfertility (and ultimately reproductive isolation), motivated a new series of theoretical and empirical studies dedicated to understand their role in human genome evolution and to explore their possible association to complex genetic disorders. With this review, we attempt to describe the latest methodological improvements to inversions detection at a genome wide level, while exploring some of the possible implications of inversion rearrangements on the evolution of the human genome. PMID:23730202

Strategies for Managing a Multigenerational Workforce

NASA Astrophysics Data System (ADS)

Iden, Ronald

The multigenerational workforce presents a critical challenge for business managers, and each generation has different expectations. A human resource management study of organizations with more than 500 employees reported 58% of the managers experiencing conflict between younger and older workers. The purpose of this single case study was to explore the multigenerational strategies used by 3 managers from a Franklin County, Ohio manufacturing facility with a population size of 6 participants. The conceptual framework for this study was built upon generational theory and cohort group theory. The data were collected through face-to-face semistructured interviews, company documents, and a reflexive journal. Member checking was completed to strengthen the credibility and trustworthiness of the interpretation of participants' responses. A modified van Kaam method enabled separation of themes following the coding of data. Four themes emerged from the data: (a) required multigenerational managerial skills, (b) generational cohort differences, (c) most effective multigenerational management strategies, and (d) least effective multigenerational management strategies. Findings from this study may contribute to social change through better understanding, acceptance, and appreciation of the primary generations in the workforce, and, in turn, improve community relationships.

What Can the Brain Teach Us about Winemaking? An fMRI Study of Alcohol Level Preferences

PubMed Central

Frost, Ram; Quiñones, Ileana; Veldhuizen, Maria; Alava, Jose-Iñaki; Small, Dana; Carreiras, Manuel

2015-01-01

Over the last few decades, wine makers have been producing wines with a higher alcohol content, assuming that they are more appreciated by consumers. To test this hypothesis, we used functional magnetic imaging to compare reactions of human subjects to different types of wine, focusing on brain regions critical for flavor processing and food reward. Participants were presented with carefully matched pairs of high- and low-alcohol content red wines, without informing them of any of the wine attributes. Contrary to expectation, significantly greater activation was found for low-alcohol than for high-alcohol content wines in brain regions that are sensitive to taste intensity, including the insula as well as the cerebellum. Wines were closely matched for all physical attributes except for alcohol content, thus we interpret the preferential response to the low-alcohol content wines as arising from top-down modulation due to the low alcohol content wines inducing greater attentional exploration of aromas and flavours. The findings raise intriguing possibilities for objectively testing hypotheses regarding methods of producing a highly complex product such as wine. PMID:25785844

What can the brain teach us about winemaking? An fMRI study of alcohol level preferences.

PubMed

Frost, Ram; Quiñones, Ileana; Veldhuizen, Maria; Alava, Jose-Iñaki; Small, Dana; Carreiras, Manuel

2015-01-01

Over the last few decades, wine makers have been producing wines with a higher alcohol content, assuming that they are more appreciated by consumers. To test this hypothesis, we used functional magnetic imaging to compare reactions of human subjects to different types of wine, focusing on brain regions critical for flavor processing and food reward. Participants were presented with carefully matched pairs of high- and low-alcohol content red wines, without informing them of any of the wine attributes. Contrary to expectation, significantly greater activation was found for low-alcohol than for high-alcohol content wines in brain regions that are sensitive to taste intensity, including the insula as well as the cerebellum. Wines were closely matched for all physical attributes except for alcohol content, thus we interpret the preferential response to the low-alcohol content wines as arising from top-down modulation due to the low alcohol content wines inducing greater attentional exploration of aromas and flavours. The findings raise intriguing possibilities for objectively testing hypotheses regarding methods of producing a highly complex product such as wine.

Mind, brain and body. Healing trauma: the way forward.

PubMed

Wilkinson, Margaret

2017-09-01

The paper explores an interdisciplinary whole person approach to healing from trauma that conserves our rich inheritance from Jung but also takes on board insights from research in the areas of attachment, trauma and the neurobiology of emotion. It is now over 20 years since insights from neurobiology began to be used to inform clinical practice. The paper reviews key insights which have emerged, along with the ways they enable therapists to help mind, brain and body to heal and the ways in which they clarify why, in clinical practice, we do what we do. Traditionally the emphasis has been on words, interpretations, and meaning-making. Currently there is greater appreciation of the affective, relational, embodied aspects of therapeutic work and the way in which these relate to traumatic early interactive experience that is held outside of human awareness. The ways in which knowledge of particular systems of connectivity inform understanding of the whole mind-brain-body relationship are examined. The way forward for clinical practice to become more focused in order to help clients to heal in mind and body is reviewed. © 2017, The Society of Analytical Psychology.

Human genetic resistance to malaria.

PubMed

Williams, Thomas N

2009-01-01

This brief chapter highlights the need for caution when designing and interpreting studies aimed at seeking new genes that may be associated with malaria protection, or investigating the potential mechanisms for protection in promising candidates. Judging genetic effects on the basis of the wrong clinical phenotype and missing true protective genes because their protective effects are masked by unpredictable epistatic effects are major potential pitfalls. These issues are by no means unique to malaria: in recent years, the importance of larger sample sizes and careful phenotypic definitions have become appreciated increasingly, particularly for genome-wide studies of complex diseases (Cordell and Clayton, 2005; Burton, Tobin and Hopper, 2005). Until recently, research in the field of malaria genetics has not enjoyed the sort of funding afforded to similar work investigating diseases of importance to the developed world. However, in the last few years, coupled with advances in genetic diagnostics that have led to massive automation and falling costs per gene explored, momentum has grown towards more generous funding that brings with it the opportunity for much larger, multisite cohesive studies. The stage is set for a giant leap forward in the coming years.

Brave new world revisited revisited: Huxley's evolving view of behaviorism

PubMed Central

Newman, Bobby

1992-01-01

Aldous Huxley's Brave New World has served as a popular and powerful source of antibehavioral sentiment. Several of Huxley's works are examined in order to ascertain his true thoughts regarding behaviorism. Early in his career Huxley failed to appreciate aspects of behavioral theory (e.g., an appreciation of heredity) or the good ends to which it could be employed. Huxley's later works portrayed behaviorism in a much more positive light, and he believed that behavioral science, along with spiritual enlightenment, might help save humanity from the Brave New World he predicted. PMID:22478115

The Nature of Geography and Its Perspectives in AP® Human Geography

ERIC Educational Resources Information Center

Murphy, Alexander B.; Hare, Phillip R.

2016-01-01

AP Human Geography students need to develop an understanding of what it means to examine the world around them from a geographic perspective. Focusing attention on geography's concern with spatial relationships, place characteristics, and geographic context helps student appreciate the nature of the discipline and the insights it offers. These…

Immanuel Kant's Account of Cognitive Experience and Human Rights Education

ERIC Educational Resources Information Center

Bynum, Gregory Lewis

2012-01-01

In this essay Gregory Bynum seeks to show that Immanuel Kant's thought, which was conceived in an eighteenth-century context of new, and newly widespread, pressures for nationally institutionalized human rights-based regimes (the American and French revolutions being the most prominent examples), can help us think in new and appreciative ways…

Chinese Cultural Dynamics and Childhood: Towards a New Individuality for Education

ERIC Educational Resources Information Center

Zhao, Guoping

2010-01-01

This paper explores, through the lens of childhood, the Chinese cultural dynamics that encourage harmonious human relationships at the price of individual development and yet support a deep appreciation of natural human experiences that allows room for the development of individuality. The purpose of such investigation is to reexamine our cultural…

Evolutionary Determinants of Genetic Variation in Susceptibility to Infectious Diseases in Humans

PubMed Central

Baker, Christi; Antonovics, Janis

2012-01-01

Although genetic variation among humans in their susceptibility to infectious diseases has long been appreciated, little focus has been devoted to identifying patterns in levels of variation in susceptibility to different diseases. Levels of genetic variation in susceptibility associated with 40 human infectious diseases were assessed by a survey of studies on both pedigree-based quantitative variation, as well as studies on different classes of marker alleles. These estimates were correlated with pathogen traits, epidemiological characteristics, and effectiveness of the human immune response. The strongest predictors of levels of genetic variation in susceptibility were disease characteristics negatively associated with immune effectiveness. High levels of genetic variation were associated with diseases with long infectious periods and for which vaccine development attempts have been unsuccessful. These findings are consistent with predictions based on theoretical models incorporating fitness costs associated with the different types of resistance mechanisms. An appreciation of these observed patterns will be a valuable tool in directing future research given that genetic variation in disease susceptibility has large implications for vaccine development and epidemiology. PMID:22242158

A Dimeric Mutant of Human Pancreatic Ribonuclease with Selective Cytotoxicity toward Malignant Cells

NASA Astrophysics Data System (ADS)

Piccoli, Renata; di Gaetano, Sonia; de Lorenzo, Claudia; Grauso, Michela; Monaco, Carmen; Spalletti-Cernia, Daniela; Laccetti, Paolo; Cinatl, Jaroslav; Matousek, Josef; D'Alessio, Giuseppe

1999-07-01

Monomeric human pancreatic RNase, devoid of any biological activity other than its RNA degrading ability, was engineered into a dimeric protein with a cytotoxic action on mouse and human tumor cells, but lacking any appreciable toxicity on mouse and human normal cells. This dimeric variant of human pancreas RNase selectively sensitizes to apoptotic death cells derived from a human thyroid tumor. Because of its selectivity for tumor cells, and because of its human origin, this protein represents a potentially very attractive, novel tool for anticancer therapy.

The habits of roots: what's up down under?

NASA Technical Reports Server (NTRS)

Feldman, L. J.

1988-01-01

Defining interactions of roots with the surrounding soil environment has been the focus of many recent investigations. As a result of these efforts, we are gaining an appreciation of the varied and often surprising strategies whereby roots adjust to and condition their soil environment for optimal growth and development. This article summarizes current knowledge of the often complex interactions between roots and biotic and abiotic factors within the soil. These interactions are interpreted in terms of modifications in the development or the physiology of the root.

An Analysis of the Populations of the Air Force’s Medical and Professional Officer Corps

DTIC Science & Technology

2010-01-01

since 1978. (See pp. 3–4.) Since 1978, the Chaplain and Dental Corps have declined in rough parallel to the Air Force’s overall active-duty...prior to entering the medical and professional corps has been most common in the MSC and BSC and least common in the Dental Corps. Attrition between...interpretation to those statuses and trends. (See pp. 33–34.) xv Acknowledgments The authors appreciate the assistance of John Park, Lt Col William

Harnessing our very life.

PubMed

Wills, Peter R; Williams, David L F; Trussell, Denys; Mann, L R B

2013-01-01

The Aristotelian ideas of nature (physis) and technology (techné) are taken as a starting point for understanding what it would mean for technology to be truly living. Heidegger's critique of the conflation of scientific and technological thinking in the current era is accepted as demonstrating that humanity does not have a deep enough appreciation of the nature of life to harness its essence safely. Could the vision of harnessing life be realized, which we strongly doubt, living technology would give selected humans transforming powers that could be expected to exacerbate, rather than solve, current global problems. The source of human purposefulness, and hence of both technology and ethics, is identified in nature's emergent capability to instantiate informational representations in material forms. Ethics that are properly grounded in an appreciation of intrinsic value, especially that of life, demand that proposals to give humanity the capabilities of living technology address the social, political, economic, and environmental problems inherent in its development and potential deployment. Before any development is embarked on, steps must be taken to avoid living technology, whatever the term eventually designates, becoming available for destructive or antisocial purposes such as those that might devastate humanity or irrevocably damage the natural world.

Fatalities due to indigenous and exotic species in Florida.

PubMed

Wolf, Barbara C; Harding, Brett E

2014-01-01

Florida's climate is suitable for many potentially hazardous animals, including both indigenous and exotic species, which are frequently kept as in zoos or as pets. This has resulted in many unforeseen fatal encounters between animals and the ever expanding human population. While the literature and knowledge pool for more common types of deaths referred to medical examiner/coroner's offices is abundant, the appreciation of wildlife and exotic pet-related deaths is far less widespread. We report seven animal attack-related deaths that occurred in Florida. The inflicted injuries included blunt and sharp force injuries, asphyxia, drowning, and envenomation. The underlying cause of death, however, was always a result of the human/animal interaction and in many cases related to human error and failure to appreciate the potentially dangerous behavior of nondomesticated species. These cases illustrate the varied circumstances and pathophysiologies associated with deaths due to indigenous and exotic species and the importance of the multidisciplinary approach in the medicolegal investigation of these cases. © 2013 American Academy of Forensic Sciences.

Nonlesions, misdiagnoses, missed diagnoses, and other interpretive challenges in fish histopathology studies: a guide for investigators, authors, reviewers, and readers

USGS Publications Warehouse

Wolf, Jeffrey C.; Baumgartner, Wes A.; Blazer, Vicki; Camus, Alvin C.; Engelhardt, Jeffrey A.; Fournie, John W.; Frasca, Salvatore; Groman, David B.; Kent, Michael L.; Khoo, Lester H.; Law, Jerry M.; Lombardini, Eric D.; Ruehl-Fehlert, Christine; Segner, Helmut E.; Smith, Stephen A.; Spitsbergen, Jan M.; Weber, Klaus; Wolfe, Marilyn J.

2015-01-01

Differentiating salient histopathologic changes from normal anatomic features or tissue artifacts can be decidedly challenging, especially for the novice fish pathologist. As a consequence, findings of questionable accuracy may be reported inadvertently, and the potential negative impacts of publishing inaccurate histopathologic interpretations are not always fully appreciated. The objectives of this article are to illustrate a number of specific morphologic findings in commonly examined fish tissues (e.g., gills, liver, kidney, and gonads) that are frequently either misdiagnosed or underdiagnosed, and to address related issues involving the interpretation of histopathologic data. To enhance the utility of this article as a guide, photomicrographs of normal and abnormal specimens are presented. General recommendations for generating and publishing results from histopathology studies are additionally provided. It is hoped that the furnished information will be a useful resource for manuscript generation, by helping authors, reviewers, and readers to critically assess fish histopathologic data.

The structural, connectomic and network covariance of the human brain.

PubMed

Irimia, Andrei; Van Horn, John D

2013-02-01

Though it is widely appreciated that complex structural, functional and morphological relationships exist between distinct areas of the human cerebral cortex, the extent to which such relationships coincide remains insufficiently appreciated. Here we determine the extent to which correlations between brain regions are modulated by either structural, connectomic or network-theoretic properties using a structural neuroimaging data set of magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) volumes acquired from N=110 healthy human adults. To identify the linear relationships between all available pairs of regions, we use canonical correlation analysis to test whether a statistically significant correlation exists between each pair of cortical parcels as quantified via structural, connectomic or network-theoretic measures. In addition to this, we investigate (1) how each group of canonical variables (whether structural, connectomic or network-theoretic) contributes to the overall correlation and, additionally, (2) whether each individual variable makes a significant contribution to the test of the omnibus null hypothesis according to which no correlation between regions exists across subjects. We find that, although region-to-region correlations are extensively modulated by structural and connectomic measures, there are appreciable differences in how these two groups of measures drive inter-regional correlation patterns. Additionally, our results indicate that the network-theoretic properties of the cortex are strong modulators of region-to-region covariance. Our findings are useful for understanding the structural and connectomic relationship between various parts of the brain, and can inform theoretical and computational models of cortical information processing. Published by Elsevier Inc.

Language: A Theme Guide to K-12 Curricular Resources, Activities, and Processes.

ERIC Educational Resources Information Center

Stanford Univ., CA. Stanford Program on International and Cross Cultural Education.

This guide is for educators who wish to improve existing curricular frameworks about teaching about language. The guide is anchored by five goal statements for student learning: (1) to investigate the origin and early development of human communication systems; (2) to gain an appreciation for the rich variety of ways in which humans convey…

Losing Sleep to Watch the Night-Sky: The Relationship between Sleep-Length and Noctcaelador

ERIC Educational Resources Information Center

Kelly, William E.; Rose, Callie

2005-01-01

For most of history, humans have been watching the night-sky (Hawkins, 1983). Historically, individuals have watched the night-sky for aesthetic appreciation and to gain insights and knowledge (Brecher & Feirtag, 1979). Despite the long history of night-sky watching among humans and the apparent importance of the behavior to large groups of…

Gratitude in Youth: A Review of Gratitude Interventions and Some Ideas for Applications

ERIC Educational Resources Information Center

Froh, Jeffrey J.; Bono, Giacomo

2011-01-01

Offering and receiving help are fundamental to human survival. The fact that children engage in beneficial social exchanges before they can even fully appreciate them underscores the importance of cooperation and altruism for human society. Gratitude is a higher-level moral emotion that enables people to notice, understand, and capitalize on…

Man and His Creative Awareness: An Approach to the Humanities.

ERIC Educational Resources Information Center

Institute for Services to Education, Inc., Washington, DC.

As part of the Thirteen-College Curriculum Program (TCCP), this teacher's manual contains background material and teaching suggestions for a sophomore-level course in humanities for predominately black colleges. The objective of the course is to train students to appreciate the arts, view art as one of the few channels through which men still…

Could ecological thresholds of toxicological concern (eco-TTCs) be used to support development of ambient water quality criteria?

EPA Science Inventory

The Threshold of Toxicologic Concern (TTC) is an approach used for a decades in human hazard assessment. A TTC establishes an exposure level for a chemical below which no appreciable risk to human health is expected based upon a de minimis value for toxicity identified for many ...

A decision support system and rule-based algorithm to augment the human interpretation of the 12-lead electrocardiogram.

PubMed

Cairns, Andrew W; Bond, Raymond R; Finlay, Dewar D; Guldenring, Daniel; Badilini, Fabio; Libretti, Guido; Peace, Aaron J; Leslie, Stephen J

The 12-lead Electrocardiogram (ECG) has been used to detect cardiac abnormalities in the same format for more than 70years. However, due to the complex nature of 12-lead ECG interpretation, there is a significant cognitive workload required from the interpreter. This complexity in ECG interpretation often leads to errors in diagnosis and subsequent treatment. We have previously reported on the development of an ECG interpretation support system designed to augment the human interpretation process. This computerised decision support system has been named 'Interactive Progressive based Interpretation' (IPI). In this study, a decision support algorithm was built into the IPI system to suggest potential diagnoses based on the interpreter's annotations of the 12-lead ECG. We hypothesise semi-automatic interpretation using a digital assistant can be an optimal man-machine model for ECG interpretation. To improve interpretation accuracy and reduce missed co-abnormalities. The Differential Diagnoses Algorithm (DDA) was developed using web technologies where diagnostic ECG criteria are defined in an open storage format, Javascript Object Notation (JSON), which is queried using a rule-based reasoning algorithm to suggest diagnoses. To test our hypothesis, a counterbalanced trial was designed where subjects interpreted ECGs using the conventional approach and using the IPI+DDA approach. A total of 375 interpretations were collected. The IPI+DDA approach was shown to improve diagnostic accuracy by 8.7% (although not statistically significant, p-value=0.1852), the IPI+DDA suggested the correct interpretation more often than the human interpreter in 7/10 cases (varying statistical significance). Human interpretation accuracy increased to 70% when seven suggestions were generated. Although results were not found to be statistically significant, we found; 1) our decision support tool increased the number of correct interpretations, 2) the DDA algorithm suggested the correct interpretation more often than humans, and 3) as many as 7 computerised diagnostic suggestions augmented human decision making in ECG interpretation. Statistical significance may be achieved by expanding sample size. Copyright © 2017 Elsevier Inc. All rights reserved.

[Emergent topics of educators' perspectives on their own education for retired health care professionals].

PubMed

Lourdes, C; Reus, Velázquez

2002-09-01

The purpose of the study was to explore the nature of seven retired educators' perspectives on their own education. Each educator was from a different health profession. Berger and Luckmann's thesis on the social construction of reality served as the conceptual framework of the study Throughout the study the researcher was able to appreciate that even though the reality of everyday life is a subjective interpretation of the world, there is a continuous correspondence between the researcher's perceptions of meaning and those of others. The in-depth interview method provided an adequate mechanism for the reconstruction of participants' everyday life experiences, and for the construction of categories of meaning. The researcher applied the method of inductive analysis in the identification of the themes and issues and in the construction of the categories. Nine categories of meaning emerged from the participants' reconstruction: 1) the legitimization of retirement; 2) understandings surrounding one's education; 3) understanding of the human aging process; 4) the legitimization of death; 5) the bonds between human beings as a fundamental element of human reality; 6) the roles within, and the objectification of, human activity; 7) the legitimization of religion and the element of spirituality; 8) understandings surrounding one's self; and 9) the reconstruction of the past: traditions and legitimate practices. Within the categories are areas of convergence between the signification of "one's own education" as a modality of life, and the signification of learning and of its propitiatory and restrictive conditions. As to the understandings of meaning and the emergent categories of meaning, the researcher constructed specific educational recommendations, which emphasize the educational processes of the old adult.

Inflammation in acute and chronic pancreatitis.

PubMed

Habtezion, Aida

2015-09-01

This report reviews recent animal model and human studies associated with inflammatory responses in acute and chronic pancreatitis. Animal model and limited human acute and chronic pancreatitis studies unravel the dynamic nature of the inflammatory processes and the ability of the immune cells to sense danger and environmental signals. In acute pancreatitis, such molecules include pathogen-associated molecular pattern recognition receptors such as toll-like receptors, and the more recently appreciated damage-associated molecular pattern molecules or 'alarmin' high mobility group box 1 and IL-33. In chronic pancreatitis, a recent understanding of a critical role for macrophage-pancreatic stellate cell interaction offers a potential targetable pathway that can alter fibrogenesis. Microbiome research in pancreatitis is a new field gaining interest but will require further investigation. Immune cell contribution to the pathogenesis of acute and chronic pancreatitis is gaining more appreciation and further understanding in immune signaling presents potential therapeutic targets that can alter disease progression.

The Implications of Arendt's Concept of Judgment for Humanistic Teaching in a Postmetaphysical Age

ERIC Educational Resources Information Center

Kwak, Duck-Joo

2015-01-01

In this essay, Duck-Joo Kwak draws on Hannah Arendt's concept of judgment in exploring what it means to teach the humanities as a form of values education in a postmetaphysical age. Arendt's concept of judgment is closely related to Ciceronian humanism, which is concerned with the wisdom to choose one's company while appreciating this pursuit…

Comments on "place and human development" by Paul Shepard and Yi-Fu Tuan's "experience and appreciation"

Treesearch

Florence C. Ladd

1977-01-01

Paul Shepard presents a dazzling array of profound ideas about the nature of the relationship between early developmental stages and places experienced in a variety of cultures. Shepard's analysis is related to the schema presented in Spivack's (1973) paper, in which he identifies some basic requirements of the human species and the environmental conditions...

Human disturbances of waterfowl: causes, effects, and management

USGS Publications Warehouse

Korschgen, C.E.; Dahlgren, R.B.

1992-01-01

Human disturbances of waterfowl can be intentional or unintentional. They may result from overt or directed activities or may be ancillary to activities not initially thought to be of concern to birds. Some of these disturbances are manifested by alertness, fright (obvious or inapparent), flight, swimming, disablement, or death. Therefore, persons responsible for waterfowl management areas should be aware of the problems from human disturbance and should design management and facilities that increase public appreciation of waterfowl.

THE EXPRESSION OF MULTIPLE FUNCTIONS IN URBAN FORESTED WETLANDS

EPA Science Inventory

Forested wetlands in metropolitan areas function to support biodiversity, protect water quality, store floodwaters, and maintain streamflow, but they also function to provide natural areas for passive recreation, education, and esthetic appreciation for the surrounding human popu...

Premeds Abroad.

ERIC Educational Resources Information Center

Rossel, Todd

1987-01-01

Foreign study can broaden the undergraduate experience for premedical students and help remedy the problem of on-campus tunnel vision, characterized by too little independent learning and critical thinking, premature specialization, avoidance of social sciences and humanities, and lack of appreciation of cultural heritage. (MSE)

Defining a stem cell hierarchy in the intestine: markers, caveats and controversies

PubMed Central

Smith, Nicholas R.; Gallagher, Alexandra C.

2016-01-01

Abstract The past decade has appreciated rapid advance in identifying the once elusive intestinal stem cell (ISC) populations that fuel the continual renewal of the epithelial layer. This advance was largely driven by identification of novel stem cell marker genes, revealing the existence of quiescent, slowly‐ and active‐cycling ISC populations. However, a critical barrier for translating this knowledge to human health and disease remains elucidating the functional interplay between diverse stem cell populations. Currently, the precise hierarchical and regulatory relationships between these ISC populations are under intense scrutiny. The classical theory of a linear hierarchy, where quiescent and slowly‐cycling stem cells self‐renew but replenish an active‐cycling population, is well established in other rapidly renewing tissues such as the haematopoietic system. Efforts to definitively establish a similar stem cell hierarchy within the intestinal epithelium have yielded conflicting results, been difficult to interpret, and suggest non‐conventional alternatives to a linear hierarchy. While these new and potentially paradigm‐shifting discoveries are intriguing, the field will require development of a number of critical tools, including highly specific stem cell marker genes along with more rigorous experimental methodologies, to delineate the complex cellular relationships within this dynamic organ system. PMID:26864260

Treating first episode psychosis--the service users' perspective: a focus group evaluation.

PubMed

O'Toole, M S; Ohlsen, R I; Taylor, T M; Purvis, R; Walters, J; Pilowsky, L S

2004-06-01

UK national guidance has prioritized developing specialist services for first episode psychosis. Such services are in the early stages of development and a definitive treatment model has yet to be established. The aim of this study was to explore service users' experiences of a first episode intervention designed along evidence-based 'best practice' guidelines and to establish specific elements seen as effective to help inform future service planning and provision. Twelve users of a specialist first episode service participated in focus groups. These were then analyzed using Interpretative Phenomenological Analysis, a specialized form of content analysis. Key elements identified by the service users included the 'human' approach as a key to the recovery process, being involved in treatment decisions, flexibility of appointments, high nurse to patient ratio, reduction in psychotic symptoms, increased confidence and independence and the provision of daily structure. To our knowledge, this is the first systematic qualitative evaluation of users' experience of a specialist first episode treatment intervention. Our findings indicate that adherence to best practice guidelines was appreciated. Regular focus groups provide a continuous audit cycle incorporating service improvements in line with government recommendations, centrally informed by the service users' and caregivers' perspective.

New insights into the interplay between the translation machinery and nonsense-mediated mRNA decay factors.

PubMed

Raimondeau, Etienne; Bufton, Joshua C; Schaffitzel, Christiane

2018-06-19

Faulty mRNAs with a premature stop codon (PTC) are recognized and degraded by nonsense-mediated mRNA decay (NMD). Recognition of a nonsense mRNA depends on translation and on the presence of NMD-enhancing or the absence of NMD-inhibiting factors in the 3'-untranslated region. Our review summarizes our current understanding of the molecular function of the conserved NMD factors UPF3B and UPF1, and of the anti-NMD factor Poly(A)-binding protein, and their interactions with ribosomes translating PTC-containing mRNAs. Our recent discovery that UPF3B interferes with human translation termination and enhances ribosome dissociation in vitro , whereas UPF1 is inactive in these assays, suggests a re-interpretation of previous experiments and modification of prevalent NMD models. Moreover, we discuss recent work suggesting new functions of the key NMD factor UPF1 in ribosome recycling, inhibition of translation re-initiation and nascent chain ubiquitylation. These new findings suggest that the interplay of UPF proteins with the translation machinery is more intricate than previously appreciated, and that this interplay quality-controls the efficiency of termination, ribosome recycling and translation re-initiation. © 2018 The Author(s).

The Function of Scientific and Humanistic Ideologies in the Counseling Profession from the Perspective of Cognitive-Experiential Self-Theory: A Response to Hansen

ERIC Educational Resources Information Center

Suthakaran, V.

2012-01-01

In this response, the author addresses Hansen's (2012) call for the counseling profession to substitute science with humanities as its primary ideology. The author uses Epstein's (1994) cognitive-experiential self-theory to show that an equal appreciation for science and humanities is more congruent with a holistic humanistic vision for…

Historical and cultural aspects of the provision of care at an indigenous healthcare service facility.

PubMed

Ribeiro, Aridiane Alves; Arantes, Cássia Irene Spinelli; Gualda, Dulce Maria Rosa; Rossi, Lídia Aparecida

2017-06-01

This case study aimed to interpret the underlying historical and cultural aspects of the provision of care at an indigenous healthcare service facility. This is an interpretive, case study-type research with qualitative approach, which was conducted in 2012 at the Indigenous Health Support Center (CASAI) of the State of Mato Grosso do Sul, Brazil. Data were collected by means systematic observation, documentary analyses and semi-structured interviews with ten health professionals. Data review was performed according to an approach based on social anthropology and health anthropology. The anthropological concepts of social code and ethnocentrism underpinned the interpretation of outcomes. Two categories were identified: CASAI, a space between streets and village; Ethnocentrism and indigenous health care. Healthcare practice and current social code are influenced by each other. The street social code prevails in the social environment under study. The institutional organization and professionals' appreciation of the indigenous biological body are decisive to provision of care under the streets social code perspective. Professionals' concepts evidence ethnocentrism in healthcare. Workers, however, try to adopt a relativized view vis-à-vis indigenous people at CASAI.

On averting the tragedy of the commons

NASA Astrophysics Data System (ADS)

De Young, Raymond; Kaplan, Stephen

1988-05-01

One of the enduring facts of the human condition is that the earth's resources are finite and its environment fragile. It is also evident that human behavior is rarely based on an appreciation of these facts. While the outlook may be bleak, so are some of the proposed solutions. Reasonable people have suggested that, to survive, an environmentally enlightened authoritarian government must be adopted. This article suggests that such a solution is unworkable, in part because it fails to consider critical aspects of human nature. A framework is proposed for developing solutions compatible with human capabilities.

Multiculturalism: Implications for Outdoor and Conservation Educators.

ERIC Educational Resources Information Center

Matthews, Bruce E.

This paper addresses the role of multiculturalism in outdoor and conservation education. Multiculturalism promotes appreciation of diversity including differences originating from race, ethnicity, gender, and abilities, thereby developing tolerance and human understanding. Several trends make multiculturalism relevant to outdoor activities. By the…

Counseling and Psychoanalysis: Advancing the Value of Diversity

ERIC Educational Resources Information Center

Hansen, James T.

2010-01-01

Arguably, the defining feature of the counseling profession is an appreciation for human diversity. Early counseling movements emphasized individual diversity, while multiculturalism and social justice highlighted cultural diversity. The author maintains that contemporary psychoanalytic thought can supply a needed intraindividual diversity…

A study of the competency of third year medical students to interpret biochemically based clinical scenarios using knowledge and skills gained in year 1 and 2.

PubMed

Gowda, Veena Bhaskar S; Nagaiah, Bhaskar Hebbani; Sengodan, Bharathi

2016-01-01

Medical students build clinical knowledge on the grounds of previously obtained basic knowledge. The study aimed to evaluate the competency of third year medical students to interpret biochemically based clinical scenarios using knowledge and skills gained during year 1 and 2 of undergraduate medical training. Study was conducted on year 3 MBBS students at AIMST University, Malaysia. Clinical scenarios (25) were constructed and administered to student volunteers, making sure at least one question from each system of year 2 was represented. Feedback was obtained on a five-point Likert scale regarding perception of learning biochemistry in MBBS year 1 versus 2. Mean score of test was 18 (72.11%). Performance was comparatively better in questions related to topics learnt in year 1 and reinforced in year 2 compared to those learnt for first time in year 2. In the feedback obtained, 31% strongly agreed and 56% agreed understanding the subject was helped more by learning biochemistry in year 2 than in year 1. Likewise, 36% strongly agreed and 56% agreed appreciating the importance of biochemistry in patient diagnosis was helped more by learning biochemistry in year 2 than year 1. Thirty one percent strongly agreed and 54% agreed that year 1 biochemistry would have been more relevant if case discussions were done simultaneously. Students retain basic science subjects better and appreciate the importance of basic sciences in patient diagnosis if they are reinforced in the context of clinical situations. © 2016 The International Union of Biochemistry and Molecular Biology.

Response to comment on "No late Quaternary strike-slip motion along the northern Karakoram fault"

NASA Astrophysics Data System (ADS)

Robinson, Alexander C.; Owen, Lewis A.; Chen, Jie; Schoenbohm, Lindsay M.; Hedrick, Kathryn A.; Blisniuk, Kimberly; Sharp, Warren D.; Imrecke, Daniel B.; Li, Wenqiao; Yuan, Zhaode; Caffee, Marc W.; Mertz-Kraus, Regina

2016-06-01

In their comment on ;No late Quaternary strike-slip motion along the northern Karakoram fault;, while Chevalier et al. (2016) do not dispute any of the results or interpretations regarding our observations along the main strand of the northern Karakoram fault, they make several arguments as to why they interpret the Kongur Shan Extensional System (KES) to be kinematically linked to the Karakoram fault. These arguments center around how an ;active; fault is defined, how slip on segments of the KES may be compatible with dextral shear related to continuation of the Karakoram fault, and suggestions as to how the two fault systems might still be connected. While we appreciate that there are still uncertainties in the regional geology, we address these comments and show that their arguments are inconsistent with all available data, known geologic relationships, and basic kinematics.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Beck, Ashley; Hunt, Kristopher; Bernstein, Hans C.

Interest in microbial communities for bioprocessing has surged in recent years based on the potential to optimize multiple tasks simultaneously and to enhance process productivity and stability. The presence and magnitude of these desirable system properties often result from interactions between functionally distinct community members. The importance of interactions, while appreciated by some disciplines for decades, has gained interest recently due to the development of ‘omics techniques, polymicrobial culturing approaches, and computational methods which has made the systems-level analysis of interacting components more tractable. This review defines and categorizes natural and engineered system components, interactions, and emergent properties, as wellmore » as presents three ecological theories relevant to microbial communities. Case studies are interpreted to illustrate components, interactions, emergent properties and agreement with theoretical concepts. A general foundation is laid to facilitate interpretation of current systems and to aid in future design of microbial systems for the next generation of bioprocesses.« less

Observing Reasonable Consumers.

ERIC Educational Resources Information Center

Silber, Norman I.

1991-01-01

Although courts and legislators usually set legal standards that correspond to empirical knowledge of human behavior, recent developments in behavioral psychology have led courts to appreciate the limits and errors in consumer decision making. "Reasonable consumer" standards that are congruent with cognitive reality should be developed.…

Causal criteria and counterfactuals; nothing more (or less) than scientific common sense.

PubMed

Phillips, Carl V; Goodman, Karen J

2006-05-26

Two persistent myths in epidemiology are that we can use a list of "causal criteria" to provide an algorithmic approach to inferring causation and that a modern "counterfactual model" can assist in the same endeavor. We argue that these are neither criteria nor a model, but that lists of causal considerations and formalizations of the counterfactual definition of causation are nevertheless useful tools for promoting scientific thinking. They set us on the path to the common sense of scientific inquiry, including testing hypotheses (really putting them to a test, not just calculating simplistic statistics), responding to the Duhem-Quine problem, and avoiding many common errors. Austin Bradford Hill's famous considerations are thus both over-interpreted by those who would use them as criteria and under-appreciated by those who dismiss them as flawed. Similarly, formalizations of counterfactuals are under-appreciated as lessons in basic scientific thinking. The need for lessons in scientific common sense is great in epidemiology, which is taught largely as an engineering discipline and practiced largely as technical tasks, making attention to core principles of scientific inquiry woefully rare.

The revolution that wasn't: a new interpretation of the origin of modern human behavior.

PubMed

Mcbrearty, S; Brooks, A S

2000-11-01

Proponents of the model known as the "human revolution" claim that modern human behaviors arose suddenly, and nearly simultaneously, throughout the Old World ca. 40-50 ka. This fundamental behavioral shift is purported to signal a cognitive advance, a possible reorganization of the brain, and the origin of language. Because the earliest modern human fossils, Homo sapiens sensu stricto, are found in Africa and the adjacent region of the Levant at >100 ka, the "human revolution" model creates a time lag between the appearance of anatomical modernity and perceived behavioral modernity, and creates the impression that the earliest modern Africans were behaviorally primitive. This view of events stems from a profound Eurocentric bias and a failure to appreciate the depth and breadth of the African archaeological record. In fact, many of the components of the "human revolution" claimed to appear at 40-50 ka are found in the African Middle Stone Age tens of thousands of years earlier. These features include blade and microlithic technology, bone tools, increased geographic range, specialized hunting, the use of aquatic resources, long distance trade, systematic processing and use of pigment, and art and decoration. These items do not occur suddenly together as predicted by the "human revolution" model, but at sites that are widely separated in space and time. This suggests a gradual assembling of the package of modern human behaviors in Africa, and its later export to other regions of the Old World. The African Middle and early Late Pleistocene hominid fossil record is fairly continuous and in it can be recognized a number of probably distinct species that provide plausible ancestors for H. sapiens. The appearance of Middle Stone Age technology and the first signs of modern behavior coincide with the appearance of fossils that have been attributed to H. helmei, suggesting the behavior of H. helmei is distinct from that of earlier hominid species and quite similar to that of modern people. If on anatomical and behavioral grounds H. helmei is sunk into H. sapiens, the origin of our species is linked with the appearance of Middle Stone Age technology at 250-300 ka. Copyright 2000 Academic Press.

Drosophila melanogaster Models of Metal-Related Human Diseases and Metal Toxicity

PubMed Central

Calap-Quintana, Pablo; González-Fernández, Javier; Sebastiá-Ortega, Noelia; Moltó, María Dolores

2017-01-01

Iron, copper and zinc are transition metals essential for life because they are required in a multitude of biological processes. Organisms have evolved to acquire metals from nutrition and to maintain adequate levels of each metal to avoid damaging effects associated with its deficiency, excess or misplacement. Interestingly, the main components of metal homeostatic pathways are conserved, with many orthologues of the human metal-related genes having been identified and characterized in Drosophila melanogaster. Drosophila has gained appreciation as a useful model for studying human diseases, including those caused by mutations in pathways controlling cellular metal homeostasis. Flies have many advantages in the laboratory, such as a short life cycle, easy handling and inexpensive maintenance. Furthermore, they can be raised in a large number. In addition, flies are greatly appreciated because they offer a considerable number of genetic tools to address some of the unresolved questions concerning disease pathology, which in turn could contribute to our understanding of the metal metabolism and homeostasis. This review recapitulates the metabolism of the principal transition metals, namely iron, zinc and copper, in Drosophila and the utility of this organism as an experimental model to explore the role of metal dyshomeostasis in different human diseases. Finally, a summary of the contribution of Drosophila as a model for testing metal toxicity is provided. PMID:28684721

Revealing Rembrandt

PubMed Central

Parker, Andrew J.

2014-01-01

The power and significance of artwork in shaping human cognition is self-evident. The starting point for our empirical investigations is the view that the task of neuroscience is to integrate itself with other forms of knowledge, rather than to seek to supplant them. In our recent work, we examined a particular aspect of the appreciation of artwork using present-day functional magnetic resonance imaging (fMRI). Our results emphasized the continuity between viewing artwork and other human cognitive activities. We also showed that appreciation of a particular aspect of artwork, namely authenticity, depends upon the co-ordinated activity between the brain regions involved in multiple decision making and those responsible for processing visual information. The findings about brain function probably have no specific consequences for understanding how people respond to the art of Rembrandt in comparison with their response to other artworks. However, the use of images of Rembrandt's portraits, his most intimate and personal works, clearly had a significant impact upon our viewers, even though they have been spatially confined to the interior of an MRI scanner at the time of viewing. Neuroscientific studies of humans viewing artwork have the capacity to reveal the diversity of human cognitive responses that may be induced by external advice or context as people view artwork in a variety of frameworks and settings. PMID:24795552

Drosophila melanogaster Models of Metal-Related Human Diseases and Metal Toxicity.

PubMed

Calap-Quintana, Pablo; González-Fernández, Javier; Sebastiá-Ortega, Noelia; Llorens, José Vicente; Moltó, María Dolores

2017-07-06

Iron, copper and zinc are transition metals essential for life because they are required in a multitude of biological processes. Organisms have evolved to acquire metals from nutrition and to maintain adequate levels of each metal to avoid damaging effects associated with its deficiency, excess or misplacement. Interestingly, the main components of metal homeostatic pathways are conserved, with many orthologues of the human metal-related genes having been identified and characterized in Drosophila melanogaster . Drosophila has gained appreciation as a useful model for studying human diseases, including those caused by mutations in pathways controlling cellular metal homeostasis. Flies have many advantages in the laboratory, such as a short life cycle, easy handling and inexpensive maintenance. Furthermore, they can be raised in a large number. In addition, flies are greatly appreciated because they offer a considerable number of genetic tools to address some of the unresolved questions concerning disease pathology, which in turn could contribute to our understanding of the metal metabolism and homeostasis. This review recapitulates the metabolism of the principal transition metals, namely iron, zinc and copper, in Drosophila and the utility of this organism as an experimental model to explore the role of metal dyshomeostasis in different human diseases. Finally, a summary of the contribution of Drosophila as a model for testing metal toxicity is provided.

Finding Creativity in an Artificial Artist

ERIC Educational Resources Information Center

Norton, David; Heath, Derrall; Ventura, Dan

2013-01-01

Creativity is an important component of human intelligence, and imbuing artificially intelligent systems with creativity is an interesting challenge. In particular, it is difficult to quantify (or even qualify) creativity. Recently, it has been suggested that conditions for attributing creativity to a system include: appreciation, imagination, and…

Tolerance as Civility in Contemporary Workplace Diversity Initiatives

ERIC Educational Resources Information Center

Von Bergen, C. W.; Collier, George

2013-01-01

Valuing diversity emphasizes the awareness, recognition, understanding, and appreciation of human differences and revolves around creating an inclusive environment in which everyone feels esteemed. This generally takes place through a series of management education and training programs that attempt to improve interpersonal relationships among…

Climate Change: An Activity.

ERIC Educational Resources Information Center

Lewis, Garry

1995-01-01

Presents a segment of the Geoscience Education booklet, Climate Change, that contains information and activities that enable students to gain a better appreciation of the possible effects human activity has on the Earth's climate. Describes the Terrace Temperatures activity that leads students through an investigation using foraminifera data to…

Work Values System Development during Adolescence

ERIC Educational Resources Information Center

Porfeli, Erik J.

2007-01-01

Work values stability, change, and development can be appreciably reduced to a living system model [Ford, D. H. (1994). "Humans as self-constructing living systems: A developmental perspective on behavior and personality" (2nd ed.). Hillsdale, NJ: Lawrence Erlbaum Associates]. This theoretical model includes discrepancy-reducing and…

Is Beauty in the Hand of the Writer? Influences of Aesthetic Preferences through Script Directions, Cultural, and Neurological Factors: A Literature Review

PubMed Central

Page, Alexander G.; McManus, Chris; González, Carmen P.; Chahboun, Sobh

2017-01-01

Human experience surrounding the appreciation of beauty is not static. Many factors such as script direction and cultural differences directly impact whether, how and why we consider images beautiful. In an earlier study, Pérez González showed that 19th-century Iranian and Spanish professional photographers manifest lateral biases linked to reading writing direction in their compositions. The present paper aims to provide a general review on this topic and intends to highlight the most relevant studies reporting preferences in the appreciation of beauty in individuals with different reading and writing directions and belonging to different cultural backgrounds. PMID:28824504

The study of the wonderful: the first topographical mapping of vision in the brain.

PubMed

Fishman, Ronald S

2008-12-01

The conception by René Descartes of the human brain, notorious as it is for placing the soul or mind in the pineal gland, had yet within it the basic idea of the brain as a highly organized mechanism with topographical sensory mapping and different functions localized in specific areas. Descartes was directly led to this idea by his appreciation of what the retinal image conceived by Johannes Kepler implied, not only for the nature of vision, but for the operation of the brain in general. The linkage between Kepler and Descartes is not widely appreciated but is one of the best examples of synergism in the history of science.

An evolutionary cosmology for scientists--and the modern world in general.

PubMed

Charlton, Bruce G

2007-01-01

I believe that people will not feel comfortable and positive about the contemporary world until we can endorse and believe an evolutionary cosmology which is appropriate to modern conditions. A cosmology is a mythical account of the universe as it presents itself to the human mind; it needs to be poetic, symbolic, inspiring of a sense of awe and mystery. Furthermore, a complete cosmology should include the three levels of macro-, meso- and micro-cosm, in order to understand the nature of the universe, human society, and the individual's relation to them. Traditional cosmologies described an eternal underlying structure to ultimate reality--a static ideal state towards which the world ought to gravitate. However, modern life is characterized by rapid growth, novelty, destruction and fluidity of all kinds of structures, a feature which traditional static cosmologies interpret negatively and pessimistically. A modern cosmology therefore needs to be focused on underlying dynamic process instead of structure and stasis. Biologists are better placed than many to appreciate a cosmology based on evolutionary change; because this is the mainstream understanding of adaptation and diversity in the natural world. The same dynamic, neophiliac and open-ended process of 'creative destruction' can be seen at work in science, economics, and modern spirituality. But a modern cosmology will only be experienced as both deep and spontaneous when it takes the form of a mythic account that is first encountered and assimilated during childhood. Since myths arise as a consequence of human creativity; there is a vital future mythogenic role for artists in the realm of ideas, images and stories: people such as mystics, poets and philosophers--including, I hope and expect, creatively inspired scientists.

Left hand tactile agnosia after posterior callosal lesion.

PubMed

Balsamo, Maddalena; Trojano, Luigi; Giamundo, Arcangelo; Grossi, Dario

2008-09-01

We report a patient with a hemorrhagic lesion encroaching upon the posterior third of the corpus callosum but sparing the splenium. She showed marked difficulties in recognizing objects and shapes perceived through her left hand, while she could appreciate elementary sensorial features of items tactually presented to the same hand flawlessly. This picture, corresponding to classical descriptions of unilateral associative tactile agnosia, was associated with finger agnosia of the left hand. This very unusual case report can be interpreted as an instance of disconnection syndrome, and allows a discussion of mechanisms involved in tactile object recognition.

Two former faces of the moon

USGS Publications Warehouse

Wilhelms, D.E.; Davis, D.E.

1971-01-01

Systematic geologic mapping of the lunar near side has resulted in the assignment of relative ages to most visible features. As a derivative of this work, geologic and artistic interpretations have been combined to produce reconstructions of the Moon's appearance at two significant points in its history. The reconstructions, although generalized, show the Moon (1) as it probably appeared about 3.3 billion years ago after most of the mare materials had accumulated, and (2) about 4.0 billion years ago after formation of the youngest of the large multiringed basins, but prior to appreciable flooding by mare material.

Chest neoplasms with infectious etiologies.

PubMed

Restrepo, Carlos S; Chen, Melissa M; Martinez-Jimenez, Santiago; Carrillo, Jorge; Restrepo, Catalina

2011-12-28

A wide spectrum of thoracic tumors have known or suspected viral etiologies. Oncogenic viruses can be classified by the type of genomic material they contain. Neoplastic conditions found to have viral etiologies include post-transplant lymphoproliferative disease, lymphoid granulomatosis, Kaposi's sarcoma, Castleman's disease, recurrent respiratory papillomatosis, lung cancer, malignant mesothelioma, leukemia and lymphomas. Viruses involved in these conditions include Epstein-Barr virus, human herpes virus 8, human papillomavirus, Simian virus 40, human immunodeficiency virus, and Human T-lymphotropic virus. Imaging findings, epidemiology and mechanism of transmission for these diseases are reviewed in detail to gain a more thorough appreciation of disease pathophysiology for the chest radiologist.

Illuminating exemplary professionalism using appreciative inquiry dialogues between students and mentors.

PubMed

Butani, Lavjay; Bogetz, Alyssa; Plant, Jennifer

2018-05-25

To explore the types of exemplary professional behaviors and the facilitators and barriers to professional behavior discussed by student-mentor dyads during appreciative inquiry (AI) dialogs. We conducted a qualitative analysis of AI narratives discussing exemplary professional practice written by third-year medical students following a dialog with mentors. Narratives were thematically analyzed using directed content analysis to explore the types of exemplary professional behaviors discussed and the facilitators and barriers to professional practice. Narratives were coded independently by two investigators; codes were finalized, themes were derived, and a model on how exemplary professional behaviors are nurtured and reinforced was developed. Themes addressed humanism toward others and excellence, with altruism being an underlying implicit guiding principle behind professional behavior. Humanism toward self was infrequently discussed as an aspect of professionalism, but when discussed, was perceived to foster resilience. Principle-based attitudes and emotional intelligence facilitated professional behaviors. Programmatic scaffolds facilitated professional behavior and included curricula on reflective practice, mentorship, promoting learner autonomy and connectedness, and a safe environment. AI is an effective strategy that can be used to stimulate learner reflection on professionalism, humanism, and wellness and promote learner acknowledgement of positive aspects of the learning environment.

The Whole-Hand Point: The Structure and Function of Pointing From a Comparative Perspective

PubMed Central

Leavens, David A.; Hopkins, William D.

2007-01-01

Pointing by monkeys, apes, and human infants is reviewed and compared. Pointing with the index finger is a species-typical human gesture, although human infants exhibit more whole-hand pointing than is commonly appreciated. Captive monkeys and feral apes have been reported to only rarely “spontaneously” point, although apes in captivity frequently acquire pointing, both with the index finger and with the whole hand, without explicit training. Captive apes exhibit relatively more gaze alternation while pointing than do human infants about 1 year old. Human infants are relatively more vocal while pointing than are captive apes, consistent with paralinguistic use of pointing. PMID:10608565

Knowledge and Attitudes About Human Papilloma Virus (HPV) Vaccination and Cervical Cancer Screening Among Women in Rural Uganda

DTIC Science & Technology

2016-06-15

1- Knowledge and attitudes about Human Papilloma Virus (HPV) vaccination and cervical cancer screening among women in rural Uganda Authors...vaccination among parents/guardians of the vaccinated girls and to assess the attitudes to HPV vaccination among parents/guardians of the vaccinated girls...general attitude towards HPV vaccination was positive among mothers though there is still need for the populations to appreciate HPV and cervical

Avoid haste in defining human muscular Sarcocystosis

USDA-ARS?s Scientific Manuscript database

We appreciate Dr. Italiano’s [1] interest in our article [2] and agree that our case definition, described in our methods as ‘intentionally specific,’ may have resulted in the exclusion of some travelers infected with Sarcocystis nesbitti. Nevertheless, we believe published data from outbreak invest...

Reaching for Excellence.

ERIC Educational Resources Information Center

Wright, Emmett L.; Perna, Jack A.

1992-01-01

Presents the four program goals for biology set forth in the National Science Teacher Association's "A Focus on Excellence: Biology Revisited" to (1) address biosphere, human society, and individual needs; (2) encourage students to experience, understand, and appreciate of natural systems; (3) apply the basic concept of the biosphere; and (4)…

Celebrating Diversity through Multicultural Literature.

ERIC Educational Resources Information Center

Edwards, Gerry

Intended for teachers of middle school, this book offers information and activities to help students appreciate and value world events from the perspective of diverse human cultures. The goals are to provide interdisciplinary and multicultural activities that integrate language, reading, and writing skills into the five content areas of social…

The conservation physiology toolbox: status and opportunities

PubMed Central

Love, Oliver P; Hultine, Kevin R

2018-01-01

Abstract For over a century, physiological tools and techniques have been allowing researchers to characterize how organisms respond to changes in their natural environment and how they interact with human activities or infrastructure. Over time, many of these techniques have become part of the conservation physiology toolbox, which is used to monitor, predict, conserve, and restore plant and animal populations under threat. Here, we provide a summary of the tools that currently comprise the conservation physiology toolbox. By assessing patterns in articles that have been published in ‘Conservation Physiology’ over the past 5 years that focus on introducing, refining and validating tools, we provide an overview of where researchers are placing emphasis in terms of taxa and physiological sub-disciplines. Although there is certainly diversity across the toolbox, metrics of stress physiology (particularly glucocorticoids) and studies focusing on mammals have garnered the greatest attention, with both comprising the majority of publications (>45%). We also summarize the types of validations that are actively being completed, including those related to logistics (sample collection, storage and processing), interpretation of variation in physiological traits and relevance for conservation science. Finally, we provide recommendations for future tool refinement, with suggestions for: (i) improving our understanding of the applicability of glucocorticoid physiology; (ii) linking multiple physiological and non-physiological tools; (iii) establishing a framework for plant conservation physiology; (iv) assessing links between environmental disturbance, physiology and fitness; (v) appreciating opportunities for validations in under-represented taxa; and (vi) emphasizing tool validation as a core component of research programmes. Overall, we are confident that conservation physiology will continue to increase its applicability to more taxa, develop more non-invasive techniques, delineate where limitations exist, and identify the contexts necessary for interpretation in captivity and the wild. PMID:29942517

A program to interest medical students in Changhua, Taiwan in the incorporation of visual arts in medicine.

PubMed

Yang, K T; Lin, C C; Chang, L Y

2011-12-01

Visual arts have been used to facilitate the teaching of the United States Accreditation Council for Graduate Medical Education (ACGME) competencies used in some countries. Some medical students may not appreciate the usefulness of incorporating arts in medical education. Therefore, arts programs that can interest medical students are necessary. We initiated and evaluated a visual arts program at the Changhua Christian Hospital in Changhua, Taiwan, with an aim to give the students a short review of visual arts and to interest them in the incorporation of arts in medicine. A total of 110 students in clerkship or internship participated in a visual arts program with emphasis on medicine-related visual arts. Content analysis of the data from the notes made by the instructor from direct observation of students; descriptions during discussions and the written feedback from students at the end of the program was used to evaluate the effect of the program. Anonymous questionnaires were also used for self-assessment of students. Qualitative analysis of the data revealed that the course was interesting to students. Themes emerged including its helpfulness to students in interpreting paintings, enhanced empathy, increased cultural awareness, enhanced observational skills, better team work, listening and communication skills and reduced stress. Ratings on the questionnaire showed similar results. Moreover, students had an increase in their confidence and desire to interpret paintings. The structured visual arts program, with emphasis on medicine-related visual arts and other humanities subjects, was able to attract the attention of medical students. It might be helpful to improve the required skills of ACGME competencies, but further studies are needed to support these conclusions.

Relative arrival-time upper-mantle tomography and the elusive background mean

NASA Astrophysics Data System (ADS)

Bastow, Ian D.

2012-08-01

The interpretation of seismic tomographic images of upper-mantle seismic wave speed structure is often a matter of considerable debate because the observations can usually be explained by a range of hypotheses, including variable temperature, composition, anisotropy, and the presence of partial melt. An additional problem, often overlooked in tomographic studies using relative as opposed to absolute arrival-times, is the issue of the resulting velocity model's zero mean. In shield areas, for example, relative arrival-time analysis strips off a background mean velocity structure that is markedly fast compared to the global average. Conversely, in active areas, the background mean is often markedly slow compared to the global average. Appreciation of this issue is vital when interpreting seismic tomographic images: 'high' and 'low' velocity anomalies should not necessarily be interpreted, respectively, as 'fast' and 'slow' compared to 'normal mantle'. This issue has been discussed in the seismological literature in detail over the years, yet subsequent tomography studies have still fallen into the trap of mis-interpreting their velocity models. I highlight here some recent examples of this and provide a simple strategy to address the problem using constraints from a recent global tomographic model, and insights from catalogues of absolute traveltime anomalies. Consultation of such absolute measures of seismic wave speed should be routine during regional tomographic studies, if only for the benefit of the broader Earth Science community, who readily follow the red = hot and slow, blue = cold and fast rule of thumb when interpreting the images for themselves.

Human and peoples' rights: social representations among Cameroonian students.

PubMed

Pirttilä-Backman, Anna-Maija; Kassea, Raul; Sakki, Inari

2009-12-01

Social representations of human and peoples' rights were studied among Cameroonian university students (N = 666) with a questionnaire based on the UN Declaration of Human Rights and the African Charter on Human and Peoples' Rights and Duties. The respondents were asked how important and how well realized they regarded the 39 human and peoples' rights to be. A 13-factor model provided the best fit with Cameroonian students' perceptions of human and peoples' rights. Taken as a whole, our results are in line with previous quantitative studies on human rights, confirming structural similarity but also country-specific variation in the aggregation of specific rights. Moreover, our data showed that Cameroonian students value human and peoples' rights highly (M = 6.18), whereas their fulfillment is not regarded as highly (M = 5.09). Same law for all, equality and freedom, and right to work and living were highly appreciated but lowly realized rights. Higher than average in importance and realization were right to education and self-fulfillment, right to marriage and property, peoples' social and political basic rights and right to life and safety. Low in importance and realization were peoples' right to their country's natural resources and independence, right to meetings, and right to express opinion. Women appreciated the rights more than men and thought of their rights as better realized compared to men. We suggest that when women say that their rights are better fulfilled than men do, it is in comparison with the older generation, who are still very dependent on men. Nowadays, thanks to education and urbanization, young women have wider choices or opportunities for marriage and jobs. Men may feel frustrated in the context of political liberalization because the freedoms are more theoretical than fulfilled; the economic crises and cultural changes have hindered their economic domination and their prerogatives.

Weighing Evidence "Steampunk" Style via the Meta-Analyser.

PubMed

Bowden, Jack; Jackson, Chris

2016-10-01

The funnel plot is a graphical visualization of summary data estimates from a meta-analysis, and is a useful tool for detecting departures from the standard modeling assumptions. Although perhaps not widely appreciated, a simple extension of the funnel plot can help to facilitate an intuitive interpretation of the mathematics underlying a meta-analysis at a more fundamental level, by equating it to determining the center of mass of a physical system. We used this analogy to explain the concepts of weighing evidence and of biased evidence to a young audience at the Cambridge Science Festival, without recourse to precise definitions or statistical formulas and with a little help from Sherlock Holmes! Following on from the science fair, we have developed an interactive web-application (named the Meta-Analyser) to bring these ideas to a wider audience. We envisage that our application will be a useful tool for researchers when interpreting their data. First, to facilitate a simple understanding of fixed and random effects modeling approaches; second, to assess the importance of outliers; and third, to show the impact of adjusting for small study bias. This final aim is realized by introducing a novel graphical interpretation of the well-known method of Egger regression.

Beliefs, Values, Ethics and Moral Reasoning in Socio-Scientific Education

ERIC Educational Resources Information Center

Yap, Siew Fong

2014-01-01

The realisation to integrate science, ethics and morality is recognised with growing impetus in recent years (as noted with introducing the Australian Curriculum "Science as a Human Endeavour" strand), to develop sophisticated epistemologies of science, which includes an appreciation of the social context including ethical thinking. To…

Ecology in a connected world: a vision for a "network of networks"

USDA-ARS?s Scientific Manuscript database

This special issue addresses the importance of connectivity in driving ecosystem dynamics. Connectivity is defined as the transfer of materials by wind, water, humans, and animals. Although it is well-recognized that we live in a connected world, it is less well-appreciated that these interconnectio...

The Real Language Crisis

ERIC Educational Resources Information Center

Berman, Russell A.

2011-01-01

Those in America are confronting a stark alternative: either open themselves to an appreciation of human plurality and the diversity of cultures around the globe or limit themselves to a narrowly normative culture. Will American schools and colleges provide students with opportunities to learn to understand other voices, or will the educational…

Hippotherapy and Therapeutic Riding Highlight!

ERIC Educational Resources Information Center

Apel, Laura, Comp.

2007-01-01

Horses have always been appreciated by humans for their strength, beauty, and gentle demeanor. Children, especially, have gravitated toward them and many experience their first horseback riding lesson at a young age. However, horses can play a very different role in the lives of children and adults with disabilities. Hippotherapy is physical,…

Teachers Judging without Scripts, or Thinking Cosmopolitan

ERIC Educational Resources Information Center

Todd, Sharon

2007-01-01

A cosmopolitan ethic invites both an appreciation of the rich diversity of values, traditions and ways of life "and" a commitment to broad, universal principles of human rights that can secure the flourishing of that diversity. Despite the tension between universalism and particularism inherent in this outlook, it has received much…

Nonlinear Epigenetic Variance: Review and Simulations

ERIC Educational Resources Information Center

Kan, Kees-Jan; Ploeger, Annemie; Raijmakers, Maartje E. J.; Dolan, Conor V.; van Der Maas, Han L. J.

2010-01-01

We present a review of empirical evidence that suggests that a substantial portion of phenotypic variance is due to nonlinear (epigenetic) processes during ontogenesis. The role of such processes as a source of phenotypic variance in human behaviour genetic studies is not fully appreciated. In addition to our review, we present simulation studies…

Polarized light reveals stress in machined laminated plastics

NASA Technical Reports Server (NTRS)

Frankowski, J.

1967-01-01

Polarized light applied to drilled laminated plastic components exposes to the human eye the locked-in stresses that will result in fractures and delaminations when the soldering procedure takes place. This technique detects stresses early in the production cycle before appreciable man-hours are invested in an item destined for rejection.

Directions in nutritional assessment: Biomarkers and bio-indicators - providing clarity in the face of complexity

USDA-ARS?s Scientific Manuscript database

Among the greatest challenges facing the Nutrition community is integrating nutrition into all aspects of global efforts in health promotion and disease prevention. Despite compelling evidence of its importance to human development, a full appreciation of how nutrition affects health is still lackin...

Chemistry, Poetry, and Artistic Illustration: An Interdisciplinary Approach to Teaching and Promoting Chemistry

ERIC Educational Resources Information Center

Furlan, Ping Y.; Kitson, Herbert; Andes, Cynthia

2007-01-01

This article describes a successful interdisciplinary collaboration among chemistry, humanities and English faculty members, who utilized poetry and artistic illustration to help students learn, appreciate, and enjoy chemistry. Students taking general chemistry classes were introduced to poetry writing and museum-type poster preparation during one…

Case Study: eCoaching in a Corporate Environment

ERIC Educational Resources Information Center

Warner, Teri L. C.

2012-01-01

This qualitative particularistic case study was an exploration and evaluation of an online, asynchronous, non-human coaching system called an "eCoaching system." Developed by the researcher, the eCoaching system combined performance coaching with the latest technologies in eLearning. The coaching was based on the appreciative inquiry approach, and…

The Critical and the Appreciative Attitudes to Dance in Education

ERIC Educational Resources Information Center

Curl, Gordon

2005-01-01

-This paper was presented to the VII Commonwealth and International Conference on Sport, Physical Education, Recreation and Dance in Brisbane in 1982 (1200 delegates) and was subsequently published in Volume 1 (Dance) of the Conference Proceedings by the Department of Human Movement Studies, University of Queensland Australia. The Conference…

Rhizomorphic Reading: The Emergence of a New Aesthetic in Literature for Youth.

ERIC Educational Resources Information Center

Burnett, Kathleen; Dresang, Eliza T.

1999-01-01

A new approach to appreciation of children's literature supports the principles of Deleuze and Guattari used to describe human communication and employed as a metaphor for the ideal or rhizome book: connection, heterogeneity, multiplicity, asignifying rupture, cartography, and decalcomania. Examples of this new aesthetic drawn from contemporary…

Teaching Literature and Human Values in ESL: Objectives and Selection

ERIC Educational Resources Information Center

Adeyanju, Thomas K.

1978-01-01

Long-term objectives for teaching literature to the student of English as a second language include developing an appreciation for literature and forming a civilized character through the modification and enlargement of values. Short-term objectives are to provide vicarious literary experiences and to reinforce language learning. (SW)

The Phylogeny and Ontogeny of Art.

ERIC Educational Resources Information Center

Youngblood, Michael S.

1987-01-01

Argues all humans are profoundly capable of learning about, appreciating, and making art. Points out that for decades educators have stressed a nondirective approach to elementary art education in order to encourage self-expression. Concludes this approach should be re-examined; that art educators must constructively criticize children's art and…

Will we allow soil carbon to feed our needs?

USDA-ARS?s Scientific Manuscript database

Humans need many things, but unbeknownst to many of us are the intricately critical influences that soil with high organic carbon has on our life support system. Curiously, the growing possibility of trading carbon in a global marketplace may actually help us better appreciate the enormous value of...

A collagenolytic streptomycete.

PubMed

Mukhopadhyay, R P; Chandra, A L

1996-11-01

A soil streptomycete (Streptomyces sp. A11) degraded collagen isolated from bovine Achilles tendon, calf skin, human placenta, carp swim bladder and rat tail tendon and released appreciable quantities of hydroxyproline. It also degraded hide powder and vegetable tanned leather. The organism was taxonomically characterized, compared with allied species, identified and designated as Streptomyces wartii.

Interpretation and Manipulation in Human Plans.

ERIC Educational Resources Information Center

Newman, Denis; Bruce, Bertram C.

1986-01-01

Uses an analysis of children's interpretations of a complex episode of social interaction to illustrate three features that distinguish them from robot plans and that form a basis for a theory of the development of social action: human plans (1) are social, (2) operate on interpretations, and (3) are used, not just executed. (FL)

A meaningful daily life in nursing homes - a place of shelter and a space of freedom: a participatory appreciative action reflection study

PubMed Central

2014-01-01

Background Shortcomings in elderly care have been reported in many parts of the world, including Sweden. However, national guidelines for elderly care have been introduced in Sweden, which contain core values and local guarantees of dignity. These highlight the need for dignity and well-being, and organising the older person’s daily life so that they perceive it as meaningful. Therefore, the aim of the present study was to describe older persons’ experience and knowledge about obstacles, opportunities and solutions to developing a meaningful daily life for those living in nursing homes. Methods This study combined the Participatory Appreciative Action Reflection (PAAR) and hermeneutic approaches. Twenty-five older persons participated and persons with dementia or cognitive impairments were included. Repeated interviews were carried out as reflective conversations, leaving 50 interviews in total, wherein the older persons provided their analyses and reflections on a meaningful daily life. Finally, an analysis of the data was completed based on a life-world hermeneutic approach. Results We identified five tentative interpretations that describe obstacles, opportunities and solutions for a meaningful daily life. Themes 2 and 4 outline obstacles for a meaningful daily life, and Themes 1, 3 and 5 describe opportunities and solutions for a meaningful daily life: (1) Having space to be yourself; (2) No space to be yourself; (3) Belonging and security; (4) A feeling of insecurity; and (5) Longing for something to happen. In the main interpretation, we found that the five tentative interpretations are related to Tuan’s concepts of space and place, where place can be described as security and stableness, and space as freedom and openness. Conclusions The reciprocal relationship is a solution for a meaningful daily life and occurs in the interaction between staff and older persons in nursing homes. It is the balance of power, and constitutes a place of shelter and a space of freedom for a meaningful daily life. The older person must have balance between shelter and freedom to have a meaningful daily life. PMID:25050083

Cheering for Team Science | Office of Cancer Genomics

Cancer.gov

As a graduate student, my PhD thesis focused on the function of a single human gene, within a genome of some 20,000 genes. Although this sometimes made my work seem insignificant, I was reminded of how important one small piece of a large puzzle can be when I discovered all the ways the gene knockout cells were disadvantaged. Studying the basic biology of our cells made me appreciate the beautiful complexity of human biology.

THE USAF CHAPLAIN CORPS 2016 A ROADMAP TO THE FUTURE

DTIC Science & Technology

2016-03-01

there? As we look to the future I believe we must base our changes and our concepts on a new appreciation for the nature of human beings. And we...new programs and policies through the question “Are we helping the Air Force and the human resource system become more agile?”53 Current initiatives...leaders whose actions increase the health of an organization. Some of these soft leadership skills are empathy , self-awareness, self-regulation

Interpretation and Manipulation in Human Plans. Technical Report No. 317.

ERIC Educational Resources Information Center

Newman, Denis; Bruce, Bertram

Analysis of students' interpretations of a complex episode of social interaction was used to illustrate three features of human plans that distinguish them from robot plans and that form a basis for a theory of the development of social action. The features illustrated are that (1) human plans are social, (2) human plans operate on…

Inferential stereomorphology of human brain lesions

NASA Astrophysics Data System (ADS)

Gedye, John L.

1980-07-01

I very much appreciated the invitation to contribute a paper to this Symposium on Applications of Human Biostereometrics, as it provides a valuable opportunity for me to take a fresh look at a problemâ€""the cerebral localisation of psychological function"â€"in which I have been interested for many years. This interest grew out of considerations of the clinically important problem of how we should go about the task of relating the form of the changes in human behavior consequent upon damage to the human brain following, say, head injury, to the form of the changes in brain morphology which constitute that damage, and related issues.

Chest neoplasms with infectious etiologies

PubMed Central

Restrepo, Carlos S; Chen, Melissa M; Martinez-Jimenez, Santiago; Carrillo, Jorge; Restrepo, Catalina

2011-01-01

A wide spectrum of thoracic tumors have known or suspected viral etiologies. Oncogenic viruses can be classified by the type of genomic material they contain. Neoplastic conditions found to have viral etiologies include post-transplant lymphoproliferative disease, lymphoid granulomatosis, Kaposi’s sarcoma, Castleman’s disease, recurrent respiratory papillomatosis, lung cancer, malignant mesothelioma, leukemia and lymphomas. Viruses involved in these conditions include Epstein-Barr virus, human herpes virus 8, human papillomavirus, Simian virus 40, human immunodeficiency virus, and Human T-lymphotropic virus. Imaging findings, epidemiology and mechanism of transmission for these diseases are reviewed in detail to gain a more thorough appreciation of disease pathophysiology for the chest radiologist. PMID:22224176

Fiber-optic confocal reflectance microscope with miniature objective for in vivo imaging of human tissues.

PubMed

Sung, Kung-Bin; Liang, Chen; Descour, Michael; Collier, Tom; Follen, Michele; Richards-Kortum, Rebecca

2002-10-01

We have built a fiber-optic confocal reflectance microscope capable of imaging human tissues in near real time. Miniaturization of the objective lens and the mechanical components for positioning and axially scanning the objective enables the device to be used in inner organs of the human body. The lateral resolution is 2 micrometers and axial resolution is 10 micrometers. Confocal images of fixed tissue biopsies and the human lip in vivo have been obtained at 15 frames/s without any fluorescent stains. Both cell morphology and tissue architecture can be appreciated from images obtained with this microscope.

Potential Uses of Biomonitoring Data: A Case Study Using the Organophosphorus Pesticides Chlorpyrifos and Malathion

PubMed Central

Barr, Dana B.; Angerer, Jürgen

2006-01-01

Background Organophosphorus pesticides such as chlorpyrifos and malathion are widely used insecticides. They do not bioaccumulate appreciably in humans and are rapidly metabolized and excreted in the urine. In nonoccupational settings, exposures to these pesticides are typically sporadic and short-lived because the pesticides tend to degrade in the environment over time; however, dietary exposures may be more chronic. Biologic monitoring has been widely used to assess exposures, susceptibility, and effects of chlorpyrifos and malathion; thus, the information base on these compounds is data rich. For biomonitoring of exposure, chlorpyrifos and malathion have been measured in blood, but most typically their urinary metabolites have been measured. For assessing early effects and susceptibility, cholinesterase and microsomal esterase activities, respectively, have been measured. Objectives Although many biologic monitoring data have been generated and published on these chemicals, their interpretation is not straightforward. For example, exposure to environmental degradates of chlorpyrifos and malathion may potentially increase f urinary metabolite levels, thus leading to overestimation of exposure. Also, the temporal nature of the exposures makes the evaluation of both exposure and effects difficult. We present an overview of the current biomonitoring and other relevant data available on exposure to chlorpyrifos and malathion and the use of these data in various environmental public health applications. PMID:17107865

21 CFR 109.3 - Definitions and interpretations.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Definitions and interpretations. 109.3 Section 109.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION UNAVOIDABLE CONTAMINANTS IN FOOD FOR HUMAN CONSUMPTION AND FOOD-PACKAGING...

21 CFR 109.3 - Definitions and interpretations.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Definitions and interpretations. 109.3 Section 109.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION UNAVOIDABLE CONTAMINANTS IN FOOD FOR HUMAN CONSUMPTION AND FOOD-PACKAGING...

21 CFR 109.3 - Definitions and interpretations.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Definitions and interpretations. 109.3 Section 109.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION UNAVOIDABLE CONTAMINANTS IN FOOD FOR HUMAN CONSUMPTION AND FOOD-PACKAGING...

21 CFR 109.3 - Definitions and interpretations.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Definitions and interpretations. 109.3 Section 109.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION UNAVOIDABLE CONTAMINANTS IN FOOD FOR HUMAN CONSUMPTION AND FOOD-PACKAGING...

Translating transitions – how to decipher peripheral human B cell development

PubMed Central

Bemark, Mats

2015-01-01

Abstract During the last two decades our understanding of human B cell differentiation has developed considerably. Our understanding of the human B cell compartment has advanced from a point where essentially all assays were based on the presence or not of class-switched antibodies to a level where a substantial diversity is appreciated among the cells involved. Several consecutive transitional stages that newly formed IgM expressing B cells go through after they leave the bone marrow, but before they are fully mature, have been described, and a significant complexity is also acknowledged within the IgM expressing and class-switched memory B cell compartments. It is possible to isolate plasma blasts in blood to follow the formation of plasma cells during immune responses, and the importance and uniqueness of the mucosal IgA system is now much more appreciated. Current data suggest the presence of at least one lineage of human innate-like B cells akin to B1 and/or marginal zone B cells in mice. In addition, regulatory B cells with the ability to produce IL-10 have been identified. Clinically, B cell depletion therapy is used for a broad range of conditions. The ability to define different human B cell subtypes using flow cytometry has therefore started to come into clinical use, but as our understanding of human B cell development further progresses, B cell subtype analysis will be of increasing importance in diagnosis, to measure the effect of immune therapy and to understand the underlying causes for diseases. In this review the diversity of human B cells will be discussed, with special focus on current data regarding their phenotypes and functions. PMID:26243514

Decision-making Capacity for Treatment of Psychotic Patients on Long Acting Injectable Antipsychotic Treatment.

PubMed

Nystazaki, Maria; Pikouli, Katerina; Tsapakis, Eva-Maria; Karanikola, Maria; Ploumpidis, Dimitrios; Alevizopoulos, Giorgos

2018-04-01

Providing informed, consent requires patients' Decision-Making Capacity for treatment. We evaluated the Decision Making Capacity of outpatients diagnosed with schizophrenia and schizoaffective disorder on treatment with Long Acting Injectable Antipsychotic medication. This is a retrospective, cross-sectional, correlational study conducted at two Depot Clinics in Athens, Greece. Participants included 65 outpatients diagnosed with schizophrenia and schizoaffective disorder on treatment with Long Acting Injectable Antipsychotics. Over half of the participants showed poor understanding of the information given regarding their disease and treatment (Understanding subscale), however >70% seemed to comprehend the relevance of this information to their medical condition (Appreciation subscale). Moreover, half of the participants reported adequate reasoning ability (Reasoning subscale), whilst patients who gained >7% of their body weight scored statistically significantly higher in the subscales of Understanding and Appreciation. Our results suggest that there is a proportion of patients with significantly diminished Decision Making Capacity, hence a full assessment is recommended in order to track them down. Further research is needed to better interpret the association between antipsychotic induced weight gain and Decision Making Capacity in patients suffering from schizophrenia or schizoaffective disorder. Copyright © 2017 Elsevier Inc. All rights reserved.

Students' perspectives of undergraduate research methods education at three public medical schools in Uganda.

PubMed

Munabi, Ian Guyton; Buwembo, William; Joseph, Ruberwa; Peter, Kawungezi; Bajunirwe, Francis; Mwaka, Erisa Sabakaki

2016-01-01

In this study we used a model of adult learning to explore undergraduate students' views on how to improve the teaching of research methods and biostatistics. This was a secondary analysis of survey data of 600 undergraduate students from three medical schools in Uganda. The analysis looked at student's responses to an open ended section of a questionnaire on their views on undergraduate teaching of research methods and biostatistics. Qualitative phenomenological data analysis was done with a bias towards principles of adult learning. Students appreciated the importance of learning research methods and biostatistics as a way of understanding research problems; appropriately interpreting statistical concepts during their training and post-qualification practice; and translating the knowledge acquired. Stressful teaching environment and inadequate educational resource materials were identified as impediments to effective learning. Suggestions for improved learning included: early and continuous exposure to the course; more active and practical approach to teaching; and a need for mentorship. The current methods of teaching research methods and biostatistics leave most of the students in the dissonance phase of learning resulting in none or poor student engagement that results in a failure to comprehend and/or appreciate the principles governing the use of different research methods.

Corot's 'gout' and a 'gipsy' girl.

PubMed

Panush, R B; Caldwell, J R; Panush, R S

1990-09-05

Representations of rheumatic disease in art provide insight into artistic expression, help us understand the evolution and perhaps the etiology of rheumatic diseases, and remind us of great contributions by artists in adverse circumstances. We noted hand deformities characteristic of inflammatory arthritis in Jean-Baptiste-Camille Corot's Gipsy Girl With Mandolin (1870 to 1875), National Gallery of Art, Washington, DC. Corot suffered with what probably was gout beginning in 1866. We are unaware that arthritis has been observed in Corot's subjects or that Corot's depiction of arthritis has been appreciated from the perspective of his own rheumatic disease. Examination of other Corot portraits identifies some with blurred hand details consistent with the artist's style and the remainder with normal hands. These observations suggest that the artist portrayed specific anatomic abnormalities in the "Gipsy Girl's" hand, indicating familiarity with inflammatory arthritis. It is speculative whether this was Corot's own or the model's arthritis; we favor the interpretation that Corot's gout was reflected in this particular work. We thus add a new perspective to Corot's Gipsy Girl With Mandolin-a subject with arthritis, a painter knowledgeable about arthritis, and a painting that therefore might be understood at least in part from an appreciation of the artist's specific illness.

Anxiety in speakers who persist and recover from stuttering.

PubMed

Davis, Stephen; Shisca, Daniella; Howell, Peter

2007-01-01

The study was designed to see whether young children and adolescents who persist in their stutter (N=18) show differences in trait and/or state anxiety compared with people who recover from their stutter (N=17) and fluent control speakers (N=19). A fluent control group, a group of speakers who have been documented as stuttering in the past but do not stutter now and a group of speakers (also with a documented history of stuttering) who persist in their stuttering participated, all aged 10-17 years. The State-Trait Anxiety Inventory for Children was administered. There were no differences between persistent, recovered and control groups with regard to trait anxiety. The persistent group had higher state anxiety than controls and the recovered group for three out of four speaking situations. The findings are interpreted as showing that anxiety levels in certain affective states appear to be associated with the speaking problem. A reader should be able to appreciate the difference between state and trait anxiety understand views about how the role anxiety has on stuttering has changed over time appreciate different views about how anxiety affects speakers who persist and recover from stuttering see why longitudinal work is needed to study these issues.

Skin microcirculation and vasopressin infusion: a laser Doppler study

PubMed Central

Bernard, Francis; Vinet, Alain; Verdant, Colin

2006-01-01

Use of arginine vasopressin in the management of refractory vasodilatory shock has been associated with development of ischaemic skin lesions. Because of the increasing popularity of arginine vasopressin, it is important to evaluate its effects on microcirculatory blood flow. Such studies are crucial if we are to appreciate the microcirculatory consequences of our various resuscitation strategies. However, methodological issues must always be considered because they can significantly influence interpretation of the results. Some aspects of use of laser Doppler to evaluate the microcirculation are reviewed within the context of recent findings presented by Luckner and coworkers in this issue of Critical Care. PMID:16594988

On the RNG theory of turbulence

NASA Technical Reports Server (NTRS)

Lam, S. H.

1992-01-01

The Yakhot and Orszag (1986) renormalization group (RNG) theory of turbulence has generated a number of scaling law constants in reasonable quantitative agreement with experiments. The theory itself is highly mathematical, and its assumptions and approximations are not easily appreciated. The present paper reviews the RNG theory and recasts it in more conventional terms using a distinctly different viewpoint. A new formulation based on an alternative interpretation of the origin of the random force is presented, showing that the artificially introduced epsilon in the original theory is an adjustable parameter, thus offering a plausible explanation for the remarkable record of quantitative success of the so-called epsilon-expansion procedure.

Facies Interpretation and the Stratigraphic Record

NASA Astrophysics Data System (ADS)

Cisne, John

This book is a short, readable, and interesting introduction to facies analysis—or as Hallam prefers to call it, facies interpretation—in the form of an advanced undergraduate to beginning graduate level textbook. Unlike conventional textbooks on the subject, the emphasis here is not so much on the basics of sedimentation and stratigraphy as on applying the basics to sweeping, large-scale problems in tectonics, paleo-oceanography, paleoclimatology, and the history of life. This is not a comprehensive textbook. One must know the basics to appreciate it fully. But its very brevity and portability combine with its extensive bibliography to make it a particularly useful guide to recent work.

Religion and the Psychotherapeutic Relationship: Transferential and Countertransferential Dimensions

PubMed Central

Abernethy, Alexis D.; Lancia, Joseph J.

1998-01-01

The salience of religion in society and health care has received increased attention. Recent developments in psychiatry reflect a broader view of religion that includes an appreciation of its adaptive and maladaptive dimensions. An examination of religious counter- transferential and transferential reactions provides a framework for examining religious themes. Case examples illustrate the following critical factors that increase therapists' skill in working with religious themes: 1) monitoring the therapist's own attitude toward religious content, 2) attending to religious content, 3) seeking consultation, and 4) using religious content in interpretations. (The Journal of Psychotherapy Practice and Research 1998; 7:281–289) PMID:9752639

Supporting Parents' Pain Care Involvement With Their Children With Acute Lymphoblastic Leukemia: A Qualitative Interpretive Description.

PubMed

Bettle, Amanda; Latimer, Margot; Fernandez, Conrad; Hughes, Jean

Children with acute lymphoblastic leukemia experience pain from the disease, treatment, and procedures. Parents can be effective in managing their child's pain, but little is systematically known about how they do this. Appreciative inquiry was used to frame the study within a strengths-based lens and interpretive descriptive methods were used to describe pain sources, parents' pain care role, and key structures supporting parents pain care involvement. Eight paediatric oncology clinic nurses and 10 parents participated. Six key themes per group were identified. Parent themes included establishing therapeutic relationships, relearning how to care for my child, overcoming challenges and recognizing pain, learning parent specific strategies, empowering to take active pain care role, and maintaining relationships. Nurse themes included establishing therapeutic relationships, preparing parents to care for their child, facilitating pain assessment, teaching parents best pain care, empowering parents, and maintaining relationships. These findings can be used to guide clinical practice and future research.

Human Milk Surveillance and Research of Environmental Chemicals: Concepts for Consideration in Interpreting and Presenting Study Results

EPA Science Inventory

This article describes issues related to the interpretation, presentation, and use of data from human milk surveillance and research studies. It is hoped that researchers conducting human milk studies in the future will consider these concepts when formulating study conclusions a...

HUMAN MILK SURVEILLANCE AND RESEARCH OF ENVIRONMENTAL CHEMICALS: CONCEPTS FOR CONSIDERATION IN INTERPRETING AND PRESENTING STUDY RESULTS

EPA Science Inventory

This article describes issues related to the interpretation, presentation, and use of data from human milk surveillance and research studies. It is hoped that researchers conducting human milk studies in the future will consider these concepts when formulating study conclusions a...

Can you see what I am talking about? Human speech triggers referential expectation in four-month-old infants

PubMed Central

Marno, Hanna; Farroni, Teresa; Vidal Dos Santos, Yamil; Ekramnia, Milad; Nespor, Marina; Mehler, Jacques

2015-01-01

Infants’ sensitivity to selectively attend to human speech and to process it in a unique way has been widely reported in the past. However, in order to successfully acquire language, one should also understand that speech is a referential, and that words can stand for other entities in the world. While there has been some evidence showing that young infants can make inferences about the communicative intentions of a speaker, whether they would also appreciate the direct relationship between a specific word and its referent, is still unknown. In the present study we tested four-month-old infants to see whether they would expect to find a referent when they hear human speech. Our results showed that compared to other auditory stimuli or to silence, when infants were listening to speech they were more prepared to find some visual referents of the words, as signalled by their faster orienting towards the visual objects. Hence, our study is the first to report evidence that infants at a very young age already understand the referential relationship between auditory words and physical objects, thus show a precursor in appreciating the symbolic nature of language, even if they do not understand yet the meanings of words. PMID:26323990

Unmasking "Alive": Children's Appreciation of a Concept Linking All Living Things

ERIC Educational Resources Information Center

Leddon, Erin M.; Waxman, Sandra R.; Medin, Douglas L.

2008-01-01

Decades of research have documented in school-aged children a persistent difficulty apprehending an overarching biological concept that encompasses animate entities such as humans and nonhuman animals, as well as plants. This has led many researchers to conclude that young children have yet to integrate plants and animate entities into a concept…

A Content-Driven Approach to Visual Literacy: Gestalt Rediscovered.

ERIC Educational Resources Information Center

Schamber, Linda

The goal of an introductory graphics course is fundamental visual literacy, which includes learning to appreciate the power of visuals in communication and to express ideas visually. Traditional principles of design--the focus of the course--are based on more fundamental gestalt theory, which relates to human pattern-seeking behavior, particularly…

The International Dimension of Education. Background Paper II.

ERIC Educational Resources Information Center

Kentworthy, Leonard S.

A description of the probable changes in the world during the next 70 years introduces a discussion of the educational attitudes needed to produce a true world community, ideally consisting of individuals with secure personalities, deep understanding of human relationships, well rooted in their own country and culture, but with an appreciation and…

Knowledge Discovery in Chess Using an Aesthetics Approach

ERIC Educational Resources Information Center

Iqbal, Azlan

2012-01-01

Computational aesthetics is a relatively new subfield of artificial intelligence (AI). It includes research that enables computers to "recognize" (and evaluate) beauty in various domains such as visual art, music, and games. Aside from the benefit this gives to humans in terms of creating and appreciating art in these domains, there are perhaps…

Teaching Social Justice through Community Engagement

ERIC Educational Resources Information Center

Closson, Rosemary; Mullins Nelson, Barbara

2009-01-01

This research was motivated by our desire for our students to achieve a deeper appreciation for the social justice aspect of our field, adult education, and also to engage them with the community. We sought to accomplish these ends as students at two different state universities volunteered to build a home with Habitat for Humanity. Data was…

Host response to secondary bacterial infection associated with antecedent influenza virus infection in pigs – exacerbation associated with vaccination

USDA-ARS?s Scientific Manuscript database

The increasing number of annual influenza (IAV) cases, coupled with the recent IAV pandemic, has amplified concerns about its impact on human and animal health. It is appreciated that Flu is complicated by bacterial pneumonia. Vaccine-associated enhanced respiratory disease (VAERD) can occur followi...

An Ambassador on and off the Field

ERIC Educational Resources Information Center

Elfman, Lois

2009-01-01

This article features Oklahoma State University (OSU) soccer midfielder Yolanda Odenyo. Odenyo grew up in Sweden the daughter of a Swedish mother and Kenyan father. Each year, she would spend her summer months in either Kenya or Zaire. She believes her extensive travels gave her a global perspective and a strong appreciation for human rights and…

Computer Games Development and Appreciative Learning Approach in Enhancing Students' Creative Perception

ERIC Educational Resources Information Center

Eow, Yee Leng; Ali, Wan Zah bte Wan; Mahmud, Rosnaini bt.; Baki, Roselan

2010-01-01

Creativity is an important entity in developing human capital while computer games are the current generation's contemporary tool. This study focused on the teaching of computer games development in order to enhance the creative perception of secondary school children. The study applied randomised subjects, with control group experimental design,…

Participant Observation: Teaching Students the Benefits of Using a Framework

ERIC Educational Resources Information Center

Daas, Karen L.; McBride, M. Chad

2014-01-01

Participant observation is a topic covered in most Introduction to Communication Research classes and specialized courses on qualitative inquiry. However, as humans are natural observers in everyday life, students may not appreciate the importance of systematic and thoughtful observation and note taking. The purpose of the one-to-two class period…

Folksong in the Classroom. Volume III, Numbers 1-3, 1982-83.

ERIC Educational Resources Information Center

Scott, John A., Ed.; Seidman, Laurence I., Ed.

1983-01-01

The third volume of a newsletter for integrating folk music appreciation into elementary and secondary social studies, literature, and humanities courses, this publication contains three issues of the newsletter which together provide a compilation of folksongs from various historical periods and cultures. The first issue contains an article on…

A New Model for Service Projects: Bringing Power up Gambia to Wilmington Montessori

ERIC Educational Resources Information Center

Scott, Susan Hanway; Zankowsky, Linda

2009-01-01

Maria Montessori understood that, innately, children feel connected to humanity, and recognized that children appreciate opportunities to serve others. This is an important connection that parents and teachers need to continue to nourish in students, providing opportunities for those meaningful connections. But what if, in addition to feeling good…

From Spring to Winter: The How, When and Why of Mythology.

ERIC Educational Resources Information Center

Head, J. G.

Students are graduating from the public school system with little, if any, mythological background. If we are to graduate educated and informed human beings, we must not persist in pursuing our traditional unorganized attempts at teaching mythology. The appreciation of contemporary allusions to mythologies is dependent on a systematized approach.…

Imitation, Imagination and Re-Appraisal: Educating the Moral Emotions

ERIC Educational Resources Information Center

Maxwell, Bruce; Reichenbach, Roland

2005-01-01

No observer of research currents in the human sciences can fail to detect a new appreciation for the contribution of emotions to descriptions of such wide-ranging psychological phenomena as moral judgement, personal and social development and learning. Despite this, we claim that educating the emotions as a dimension of moral education remains…

Leadership through Partnership: A Collaborative, Strengths-Based Approach to Strategic Planning

ERIC Educational Resources Information Center

Randolph, Loretta H.

2006-01-01

Organization sustainability depends on the creation of innovative partnerships that engage organization members at all levels in setting strategy and achieving goals. Appreciative Inquiry (AI) is an approach to exploring what gives life to human systems when they function at their best. The use of an AI approach to strategic planning, invites…

Architecting Human Operator Trust in Automation to Improve System Effectiveness in Multiple Unmanned Aerial Vehicles (UAV) Control

DTIC Science & Technology

2009-03-01

like to extend our appreciation to our research sponsor Dr. Janet Miller from the Air Force Research Labs, and her colleague Dr. Cheryl Batchelor, for...for single-operator control of multiple UAVs. Drs. Brian Tsou, Lamar Warfield , Justin Estepp and Benjamin Knott , meanwhile, contributed to our

Marvels of Math: Fascinating Reads and Awesome Activities.

ERIC Educational Resources Information Center

Haven, Kendall F.

Any topic, math included, becomes more accessible and understandable when human stories are related about the development of the subject. Stories make subjects real and purposeful. They provide a foundation from which students can understand and appreciate mathematics rather than merely memorize a series of rote exercises. This book presents 16…

Developing Research Skills for Undergraduate Business Students: Experiential Learning on Introduction to Personnel Administration and Industrial Relations Course

ERIC Educational Resources Information Center

Figueroa, Carmen I.; González, Cándida

2014-01-01

This paper reports on research into developing research skills in human resources management of apprentices through experiential learning. The target groups were undergraduate business students registered in the Introduction to Personnel and Industrial Relations course. The research identified the appreciation level of importance and satisfaction…

Applications of the Normalization Principle in the Human Services: Implications for Social Work Education.

ERIC Educational Resources Information Center

Horejsi, Charles R.

1979-01-01

The normalization philosophy originated in Scandinavia. Described as a complex ideology, highly compatible with basic social work principles, it has much to offer social education, especially in areas of social policy and services, planning and program development, and appreciation of the importance of the social environment. (Author/MLW)

Islamic bioethics: a general scheme

PubMed Central

Shomali, Mohamamd Ali

2008-01-01

No doubt life in its all forms enjoys a very high status in Islam. Human life is one of the most sacred creatures of God. Therefore, it must be appreciated, respected and protected. In this regard, the paper refers to different parts. The first part studies the value of life in Islam. It helps to understand why life must be appreciated and respected. The second part sheds some light on the nature of the Islamic bioethics. Discussing the sources and authorities in the Islamic bioethics, in this part we will study the way of life protection which is regulated by the Islamic law and bioethics. Part three reflects on some important issues in bioethics from an Islamic perspective. Concerning the Islamic believes, physical health maintenance and disease treatment are two important aspects of the Islamic teachings. In respect to the beginning of human life; firstly, we will see that reproduction must occur in the context of a legitimate and stable family. Secondly, we will study family planning and abortion. With respect to the end of life, issues such as suicide and euthanasia will be studied. Finally organ transplantation will be discussed. PMID:23908711

Singing his praises: Darwin and his theory in song and musical production.

PubMed

Smocovitis, Vassiliki Betty

2009-09-01

This essay offers a chronological survey of the range of songs and musical productions inspired by Darwin and his theory since they entered the public sphere some 150 years ago.It draws on an unusual set of historical materials, including illustrated sheet music, lyrics and librettos, wax cylinder recordings, vinyl records, and video recordings located in digital and sound archives and on the Internet. It also offers a characterization of the varied genres and a literary analysis of the forms as a way of understanding the diverse audiences engaging, and indeed "entertaining," Darwin and the implications of his theory. It argues that the engagement with Darwin and his celebrated theory is far more creative than has been appreciated and recommends that historians of science further explore Darwin and his theory as embodied ina fuller range of cultural expressions. This will lead to an understanding of Darwin's "iconic"status that draws on a fuller range of human sensory experience and that also enables us to appreciate his--and his theory's-enduring power to engage the human imagination.

Technical Evaluation Report on the Guidance and Control Panel Symposium (29th) on Air Traffic Management Civil/Military Systems and Technologies.

DTIC Science & Technology

1980-03-01

language, reliance upon instrumental (technical) versus biologi - cal ( human ) capabilities, etc. The latter - the appreciative one - is not expressed...infrastructure, and most of human contribution, should be ready for servi- cing the military scene in case of high tension, or in the context of hostility...already proven "feasible changes*. 10 81 In a similar way of improvement ( 751 and [ 771 give additional information about DABS and a DABS/ ATARS

Interpreting the International Right to Health in a Human Rights-Based Approach to Health

PubMed Central

2016-01-01

Abstract This article tracks the shifting place of the international right to health, and human rights-based approaches to health, in the scholarly literature and United Nations (UN). From 1993 to 1994, the focus began to move from the right to health toward human rights-based approaches to health, including human rights guidance adopted by UN agencies in relation to specific health issues. There is a compelling case for a human rights-based approach to health, but it runs the risk of playing down the right to health, as evidenced by an examination of some UN human rights guidance. The right to health has important and distinctive qualities that are not provided by other rights—consequently, playing down the right to health can diminish rights-based approaches to health, as well as the right to health itself. Because general comments, the reports of UN Special Rapporteurs, and UN agencies’ guidance are exercises in interpretation, I discuss methods of legal interpretation. I suggest that the International Covenant on Economic, Social and Cultural Rights permits distinctive interpretative methods within the boundaries established by the Vienna Convention on the Law of Treaties. I call for the right to health to be placed explicitly at the center of a rights-based approach and interpreted in accordance with public international law and international human rights law. PMID:28559680

Interpreting the International Right to Health in a Human Rights-Based Approach to Health.

PubMed

Hunt, Paul

2016-12-01

This article tracks the shifting place of the international right to health, and human rights-based approaches to health, in the scholarly literature and United Nations (UN). From 1993 to 1994, the focus began to move from the right to health toward human rights-based approaches to health, including human rights guidance adopted by UN agencies in relation to specific health issues. There is a compelling case for a human rights-based approach to health, but it runs the risk of playing down the right to health, as evidenced by an examination of some UN human rights guidance. The right to health has important and distinctive qualities that are not provided by other rights-consequently, playing down the right to health can diminish rights-based approaches to health, as well as the right to health itself. Because general comments, the reports of UN Special Rapporteurs, and UN agencies' guidance are exercises in interpretation, I discuss methods of legal interpretation. I suggest that the International Covenant on Economic, Social and Cultural Rights permits distinctive interpretative methods within the boundaries established by the Vienna Convention on the Law of Treaties. I call for the right to health to be placed explicitly at the center of a rights-based approach and interpreted in accordance with public international law and international human rights law.

The Glass Menagerie as heuristic for explicating nursing theory.

PubMed

Pilkington, F Beryl; Frederickson, Keville; Velsasco-Whetsell, Martha

2006-07-01

Tennessee Williams' play, The Glass Menagerie, is interpreted through the lens of two different nursing theories, the Roy adaptation model and the human becoming theory. In the Roy adaptation model interpretation, adaptive levels of reality testing and stimuli that instigate withdrawal are explored, while in the human becoming theory interpretation, the themes of meaning, rhythmicity, and contranscendence are explicated.

What students learn about professionalism from faculty stories: an "appreciative inquiry" approach.

PubMed

Quaintance, Jennifer L; Arnold, Louise; Thompson, George S

2010-01-01

To develop a method for teaching professionalism by enabling students and faculty members to share positive examples of professionalism in a comfortable environment that reflects the authentic experiences of physicians. Medical educators struggle with the teaching of professionalism. Professionalism definitions can guide what they teach, but they must also consider how they teach it, and constructs such as explicit role modeling, situated learning, and appreciative inquiry provide appropriate models. The project consisted of students interviewing faculty members about their experiences with professionalism and then reflecting on and writing about the teachers' stories. In 2004, 62 students interviewed 33 faculty members, and 193 students observed the interviews. Using a project Web site, 36 students wrote 132 narratives based on the faculty's stories, and each student offered his or her reflections on one narrative. The authors analyzed the content of the narratives and reflections via an iterative process of independent coding and discussion to resolve disagreements. Results showed that the narratives were rich and generally positive; they illustrated a broad range of the principles contained in many definitions of professionalism: humanism, accountability, altruism, and excellence. The students' reflections demonstrated awareness of the same major principles of professionalism that the faculty conveyed. The reflections served to spark new ideas about professionalism, reinforce the values of professionalism, deepen students' relationships with the faculty, and heighten students' commitment to behaving professionally. Narrative storytelling, as a variant of appreciative inquiry, seems to be effective in deepening students' understanding and appreciation of professionalism.

The Biological Effects of Quadripolar Radiofrequency Sequential Application: A Human Experimental Study

PubMed Central

Cornaglia, Antonia Icaro; Faga, Angela; Scevola, Silvia

2014-01-01

Abstract Objective: An experimental study was conducted to assess the effectiveness and safety of an innovative quadripolar variable electrode configuration radiofrequency device with objective measurements in an ex vivo and in vivo human experimental model. Background data: Nonablative radiofrequency applications are well-established anti-ageing procedures for cosmetic skin tightening. Methods: The study was performed in two steps: ex vivo and in vivo assessments. In the ex vivo assessments the radiofrequency applications were performed on human full-thickness skin and subcutaneous tissue specimens harvested during surgery for body contouring. In the in vivo assessments the applications were performed on two volunteer patients scheduled for body contouring surgery at the end of the study. The assessment methods were: clinical examination and medical photography, temperature measurement with thermal imaging scan, and light microscopy histological examination. Results: The ex vivo assessments allowed for identification of the effective safety range for human application. The in vivo assessments allowed for demonstration of the biological effects of sequential radiofrequency applications. After a course of radiofrequency applications, the collagen fibers underwent an immediate heat-induced rearrangement and were partially denaturated and progressively metabolized by the macrophages. An overall thickening and spatial rearrangement was appreciated both in the collagen and elastic fibers, the latter displaying a juvenile reticular pattern. A late onset in the macrophage activation after sequential radiofrequency applications was appreciated. Conclusions: Our data confirm the effectiveness of sequential radiofrequency applications in obtaining attenuation of the skin wrinkles by an overall skin tightening. PMID:25244081

The biological effects of quadripolar radiofrequency sequential application: a human experimental study.

PubMed

Nicoletti, Giovanni; Cornaglia, Antonia Icaro; Faga, Angela; Scevola, Silvia

2014-10-01

An experimental study was conducted to assess the effectiveness and safety of an innovative quadripolar variable electrode configuration radiofrequency device with objective measurements in an ex vivo and in vivo human experimental model. Nonablative radiofrequency applications are well-established anti-ageing procedures for cosmetic skin tightening. The study was performed in two steps: ex vivo and in vivo assessments. In the ex vivo assessments the radiofrequency applications were performed on human full-thickness skin and subcutaneous tissue specimens harvested during surgery for body contouring. In the in vivo assessments the applications were performed on two volunteer patients scheduled for body contouring surgery at the end of the study. The assessment methods were: clinical examination and medical photography, temperature measurement with thermal imaging scan, and light microscopy histological examination. The ex vivo assessments allowed for identification of the effective safety range for human application. The in vivo assessments allowed for demonstration of the biological effects of sequential radiofrequency applications. After a course of radiofrequency applications, the collagen fibers underwent an immediate heat-induced rearrangement and were partially denaturated and progressively metabolized by the macrophages. An overall thickening and spatial rearrangement was appreciated both in the collagen and elastic fibers, the latter displaying a juvenile reticular pattern. A late onset in the macrophage activation after sequential radiofrequency applications was appreciated. Our data confirm the effectiveness of sequential radiofrequency applications in obtaining attenuation of the skin wrinkles by an overall skin tightening.

The Mirror Has Two Faces: Contradictory Reflections of Donkeys in Western Literature from Lucius to Balthazar

PubMed Central

Bough, Jill

2011-01-01

Simple Summary I argue that cultural representations of donkeys arise from the contradictory philosophies that underpin western society. Donkeys have invariable been used symbolically in a negative way in early western literature which has affected our ongoing attitudes towards them: used as allegories for human nature, their own remains largely hidden. Tracing literary representations of donkeys reveals not only their conflicting origins but also how they developed over time. Understanding how these representations have affected our treatment of donkeys may lead to a better appreciation of the actual animals. Abstract How we represent animals both reflects our attitudes towards them and affects our treatment of them. The donkey has lived alongside humans, bearing their burdens since the time of their domestication over 10,000 years ago. Despite this, they have invariably enjoyed a low status in human cultures, received little appreciation and been treated harshly. We view some animals as being more worthy than others and represent them accordingly: donkeys have been ridiculed and derided. Literary representations of donkeys from the fables of Ancient Greece to contemporary iconic texts are explored to follow the donkey through the human imaginary. These representations derive from two main, conflicting sources, Greek literature and the Bible. Examining these cultural representations may lead towards a greater understanding of the way they affect the actual animal and lead to a greater understanding of that animal and, ultimately, to better treatment of them. PMID:26486214

Involvement of the endocannabinoid system in reward processing in the human brain.

PubMed

van Hell, Hendrika H; Jager, Gerry; Bossong, Matthijs G; Brouwer, Annelies; Jansma, J Martijn; Zuurman, Lineke; van Gerven, Joop; Kahn, René S; Ramsey, Nick F

2012-02-01

Disturbed reward processing in humans has been associated with a number of disorders, such as depression, addiction, and attention-deficit hyperactivity disorder. The endocannabinoid (eCB) system has been implicated in reward processing in animals, but in humans, the relation between eCB functioning and reward is less clear. The current study uses functional magnetic resonance imaging (fMRI) to investigate the role of the eCB system in reward processing in humans by examining the effect of the eCB agonist Δ(9)-tetrahydrocannabinol (THC) on reward-related brain activity. Eleven healthy males participated in a randomized placebo-controlled pharmacological fMRI study with administration of THC to challenge the eCB system. We compared anticipatory and feedback-related brain activity after placebo and THC, using a monetary incentive delay task. In this task, subjects are notified before each trial whether a correct response is rewarded ("reward trial") or not ("neutral trial"). Subjects showed faster reaction times during reward trials compared to neutral trials, and this effect was not altered by THC. THC induced a widespread attenuation of the brain response to feedback in reward trials but not in neutral trials. Anticipatory brain activity was not affected. These results suggest a role for the eCB system in the appreciation of rewards. The involvement of the eCB system in feedback processing may be relevant for disorders in which appreciation of natural rewards may be affected such as addiction.

A compelling practice: empowering future leaders in the medical humanities.

PubMed

Runyan, Aliye; Ellington, Katherine; Wershof Schwartz, Andrea

2013-12-01

Medical students and faculty explore the medical humanities for diverse reasons: as a medium for self-reflection, a means to cultivate professionalism and humanism, and a way to gain an appreciation for the broader contexts in which illness and health occur. One important area for development is increasing the exposure of learners and clinicians of various levels of training to the medical humanities and to role models in the field. Student-led programs in the medical humanities at the American Medical Student Association (AMSA) address these needs by offering unique opportunities for learning and sharing experiences. AMSA programs connect physicians-in-training using technology to create virtual communication and learning opportunities. These include monthly book discussion webinars, the Writers' Institute and the Medical Humanities Scholars Program (MHSP).

Exploring the human emotion of feeling cared for in the workplace.

PubMed

Baggett, Margarita; Giambattista, Laura; Lobbestael, Linda; Pfeiffer, Judith; Madani, Catherina; Modir, Royya; Zamora-Flyr, Maria Magdalena; Davidson, Judy E

2016-09-01

To explore the emotion of feeling cared for in the workplace. The emotion of feeling cared for drives health-promoting behaviours. Feeling cared for is the end-product of caring, affecting practice, environment and outcomes. Identifying behaviours that lead to feeling cared for is the first step in promoting caring practices in leadership. A survey with open-ended questions was designed, validated and electronically distributed. Data from 35 responses were thematically analysed. Unit culture and leadership style affect caring capacity in the workplace. First level coding revealed two caring behaviour categories: recognition and support. Themes emerged aligned to Chapman's model of workplace appreciation: words of affirmation, receiving gifts, quality time and acts of service. The importance of being treated as a whole person was reported: being appreciated personally and professionally. Feeling cared for drives outcomes such as feeling valued, important, teamwork and organisational loyalty. This study generalises the applicability of Chapman's model developed for workplace appreciation in the health-care setting. Concrete examples of how leaders stimulate feeling cared for are provided. Caring leadership behaviours have the potential to improve retention, engagement, the healing environment and the capacity for caring for others. © 2016 John Wiley & Sons Ltd.

Toward Model Building for Visual Aesthetic Perception

PubMed Central

Lughofer, Edwin; Zeng, Xianyi

2017-01-01

Several models of visual aesthetic perception have been proposed in recent years. Such models have drawn on investigations into the neural underpinnings of visual aesthetics, utilizing neurophysiological techniques and brain imaging techniques including functional magnetic resonance imaging, magnetoencephalography, and electroencephalography. The neural mechanisms underlying the aesthetic perception of the visual arts have been explained from the perspectives of neuropsychology, brain and cognitive science, informatics, and statistics. Although corresponding models have been constructed, the majority of these models contain elements that are difficult to be simulated or quantified using simple mathematical functions. In this review, we discuss the hypotheses, conceptions, and structures of six typical models for human aesthetic appreciation in the visual domain: the neuropsychological, information processing, mirror, quartet, and two hierarchical feed-forward layered models. Additionally, the neural foundation of aesthetic perception, appreciation, or judgement for each model is summarized. The development of a unified framework for the neurobiological mechanisms underlying the aesthetic perception of visual art and the validation of this framework via mathematical simulation is an interesting challenge in neuroaesthetics research. This review aims to provide information regarding the most promising proposals for bridging the gap between visual information processing and brain activity involved in aesthetic appreciation. PMID:29270194

Regulation of adipose branched-chain amin acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity

USDA-ARS?s Scientific Manuscript database

Elevated blood branched-chain amin acids (BCAA)are often assoicated with insulin resistance and type2 diabetes, which might result from a reduced cellular utilization and/or incomplete BCAA oxidation. White adipose tissue (WAT) has become appreciated as a potential player in whole body BCAA metaboli...

Regulation of adipose branched chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity

USDA-ARS?s Scientific Manuscript database

Elevated blood branched chain amino acids (BCAA) are often associated with insulin resistance and type 2 diabetes. One possibility is that under these conditions there is a reduced cellular utilization and/or lower complete oxidation of BCAAs. White adipose tissue (WAT) has become appreciated as a...

Blue Eyes, Brown Eyes, Cornrows, and Curls: Building on Books to Explore Physical Diversity with Preschool Children

ERIC Educational Resources Information Center

Kemple, Kristen M.; Lopez, Maria

2009-01-01

Children notice physical characteristics of others and develop attitudes toward human diversity at a very young age. High-quality children's literature is a helpful springboard to encourage their awareness of differences and to develop their appreciation of uniqueness. Children's books can be an important avenue for shaping how children perceive…

Special issue: Remote sensing applications for investigations of fire regime attributes

Treesearch

Andrew T. Hudak; Andrea E. Thode; Jan W. van Wagtendonk

2007-01-01

Fire is a primary change agent in many terrestrial ecosystems. Appreciation is growing for the essential role fire plays in fire-adapted ecosystems. Nevertheless, humans living in the wildland urban interface (WUI) understandably regard fires as a threat to their safety, their property, or the natural resources and ecosystem services upon which they depend. As land...

You Want Her to Have a What?

ERIC Educational Resources Information Center

Ritter, Steve; Ritter, Frieda

2010-01-01

In this article, the authors share their experience in taking care of their daughter, Elyse, who was in and out of the hospital when she was a child, battling numerous doctors' visits. Throughout the years, Elyse has taught their family about the importance of the human spirit and that they should appreciate others for who they are, no matter what…

Plants & People: A Beneficial Relationship. Plant Life in Action[TM]. Schlessinger Science Library. [Videotape].

ERIC Educational Resources Information Center

2000

In Plants & People: A Beneficial Relationship, viewers will develop an appreciation for plant life by learning how plants provide us with the oxygen, food, shelter, clothing and medicine that we need to survive. Discover how the science of agriculture has benefited humanity for thousands of years. Examine the complex relationships that have…

Caillois's "Man, Play, and Games": An Appreciation and Evaluation

ERIC Educational Resources Information Center

Henricks, Thomas S.

2010-01-01

This article explores the contributions of Roger Caillois to the study of human play. The initial portion of the essay focuses on Caillois's scholarly career as a response to the public events and intellectual movements of his time. The author shows how Caillois's responses influenced the portraits of play that he developed in such important books…

Forest aesthetics, biodiversity, and the perceived appropriateness of ecosystem management practices

Treesearch

Paul H. Gobster

1996-01-01

The social acceptability of 'ecosystem management' and related new forestry programs hinges on how people view the forest environment and what it means to them. For many, these conceptions are based on a 'scenic aesthetic" that is dramatic and visual, where both human and natural changes are perceived negatively. In contrast, appreciation of...

Contexts and Control Operations Used in Accessing List-Specific, Generalized, and Semantic Memories

ERIC Educational Resources Information Center

Humphreys, Michael S.; Murray, Krista L.; Maguire, Angela M.

2009-01-01

The human ability to focus memory retrieval operations on a particular list, episode or memory structure has not been fully appreciated or documented. In Experiment 1-3, we make it increasingly difficult for participants to switch between a less recent list (multiple study opportunities), and a more recent list (single study opportunity). Task…

Many People, Many Ways: Understanding Cultures around the World. Volume 1.

ERIC Educational Resources Information Center

Brewer, Chris, Comp.; Grinde, Linda, Comp.

This book helps students and teachers explore the concept of culture and to appreciate the diversity of cultures of the world. The nine cultures in the book represent a variety of races and environments. Each chapter offers ideas for activities for student to explore elements of culture and common human experiences. The chapters are divided into…

In Search of an Index of Imagination for Virtual Experience Designers

ERIC Educational Resources Information Center

Liang, Chaoyun; Hsu, Yuling; Chang, Chi-Cheng; Lin, Li-Jhong

2013-01-01

Imagination is a gift to humans, and a creative faculty of the mind. Although early studies in the fields of philosophy and psychology appreciated the value of imagination, little work has been done pertaining to indicators of imagination. This study synthesized early works on imagination carried out between 1900 and 2012 to clarify its meaning…

Narrative and Chaos Acknowledging the Novelty of Lives-in-Time

ERIC Educational Resources Information Center

Randall, William L.

2007-01-01

In this paper I propose that interest in "narrative" within the human sciences is comparable to interest in "chaos" within the natural sciences. In their respective ways, theories on narrative and theories on chaos are aimed at appreciating the dynamics of complex, multi-dimensional systems which otherwise resist our attempts to predict, measure,…

Comparison of Exhaust Emissions and Their Mutagenicity from the Combustion of Biodiesel, Vegetable Oil, Gas-to-Liquid and Petrodiesel Fuels

USDA-ARS?s Scientific Manuscript database

Diesel engine emissions (DEE) are classified as probably carcinogenic to humans. In recent years every effort has been made to reduce DEE and their content of carcinogenic and mutanegnic polycycluc aromatic hydrocarbons (PAH). In several studies conducted since 1995, we observed an appreciable red...

Where the Brain Appreciates the Final State of an Event: The Neural Correlates of Telicity

ERIC Educational Resources Information Center

Romagno, Domenica; Rota, Giuseppina; Ricciardi, Emiliano; Pietrini, Pietro

2012-01-01

In this study we investigated whether the human brain distinguishes between telic events that necessarily entail a specified endpoint (e.g., "reaching"), and atelic events with no delimitation or final state (e.g., "chasing"). We used functional magnetic resonance imaging to explore the patterns of neural response associated with verbs denoting…

Experiencing Our Anatomy: Incorporating Human Biology into Dance Class via Imagery, Imagination, and Somatics

ERIC Educational Resources Information Center

Kirk, Johanna

2014-01-01

This article proposes a model for introducing biological perspectives into teaching dance as a means to encourage students toward deeper, healthier, and more personal relationships with their art form as well as appreciation for their physical and cognitive abilities, both inside and outside of the dance studio. It recommends that dance teachers…

Not for Bread Alone: An Appreciation of Job Enrichment.

ERIC Educational Resources Information Center

Taylor, Linda King

Bridging the gap between theory and practice, the author through a case-study approach of industries in the United Kingdom and Europe has identified motivation techniques resulting in job enrichment. The book is written in the belief that work is more efficient when it is enjoyable and that human beings will become obsolete unless allowed to…

Environments: The Context of Our Lives. A Social Studies Schema for Grades 7-12.

ERIC Educational Resources Information Center

Peters, Richard

Because humans and nature are inextricable entities sharing a common global lifespace, natural and social environments are interactive and interdependent. There is a need to (1) understand the origins and characteristics of lifespace phenomena; (2) perceive man and Nature relationships; (3) respect Nature; (4) appreciate the beauty of one's…

Weighing Evidence “Steampunk” Style via the Meta-Analyser

PubMed Central

Bowden, Jack; Jackson, Chris

2016-01-01

ABSTRACT The funnel plot is a graphical visualization of summary data estimates from a meta-analysis, and is a useful tool for detecting departures from the standard modeling assumptions. Although perhaps not widely appreciated, a simple extension of the funnel plot can help to facilitate an intuitive interpretation of the mathematics underlying a meta-analysis at a more fundamental level, by equating it to determining the center of mass of a physical system. We used this analogy to explain the concepts of weighing evidence and of biased evidence to a young audience at the Cambridge Science Festival, without recourse to precise definitions or statistical formulas and with a little help from Sherlock Holmes! Following on from the science fair, we have developed an interactive web-application (named the Meta-Analyser) to bring these ideas to a wider audience. We envisage that our application will be a useful tool for researchers when interpreting their data. First, to facilitate a simple understanding of fixed and random effects modeling approaches; second, to assess the importance of outliers; and third, to show the impact of adjusting for small study bias. This final aim is realized by introducing a novel graphical interpretation of the well-known method of Egger regression. PMID:28003684

Gloved Human-Machine Interface

NASA Technical Reports Server (NTRS)

Adams, Richard (Inventor); Hannaford, Blake (Inventor); Olowin, Aaron (Inventor)

2015-01-01

Certain exemplary embodiments can provide a system, machine, device, manufacture, circuit, composition of matter, and/or user interface adapted for and/or resulting from, and/or a method and/or machine-readable medium comprising machine-implementable instructions for, activities that can comprise and/or relate to: tracking movement of a gloved hand of a human; interpreting a gloved finger movement of the human; and/or in response to interpreting the gloved finger movement, providing feedback to the human.

"Fuzziness" in the celular interactome: a historical perspective.

PubMed

Welch, G Rickey

2012-01-01

Some historical background is given for appreciating the impact of the empirical construct known as the cellular protein-protein interactome, which is a seemingly de novo entity that has arisen of late within the context of postgenomic systems biology. The approach here builds on a generalized principle of "fuzziness" in protein behavior, proposed by Tompa and Fuxreiter.(1) Recent controversies in the analysis and interpretation of the interactome studies are rationalized historically under the auspices of this concept. There is an extensive literature on protein-protein interactions, dating to the mid-1900s, which may help clarify the "fuzziness" in the interactome picture and, also, provide a basis for understanding the physiological importance of protein-protein interactions in vivo.

Navigating the network: signaling cross-talk in hematopoietic cells

PubMed Central

Fraser, Iain D C; Germain, Ronald N

2009-01-01

Recent studies in hematopoietic cells have led to a growing appreciation of the diverse modes of molecular and functional cross-talk between canonical signaling pathways. However, these intersections represent only the tip of the iceberg. Emerging global analytical methods are providing an even richer and more complete picture of the many components that measurably interact in a network manner to produce cellular responses. Here we highlight the pieces in this Focus, emphasize the limitations of the present canonical pathway paradigm, and discuss the value of a systems biology approach using more global, quantitative experimental design and data analysis strategies. Lastly, we urge caution about overly facile interpretation of genome- and proteome-level studies. PMID:19295628

Spectral evolution in young active galactic nuclei

NASA Technical Reports Server (NTRS)

Boldt, E.; Leiter, D.

1986-01-01

The spectral evolution of AGNs is discussed within the context of a scenario where the cosmic X-ray background (CXB) is dominated by these sources. Attention is draqwn to the fact that the individually observed AGN X-ray spectra are significantly steeper than that of the CXB. The remarkably flat spectrum thereby required for the 'as-yet' unresolved sources of the residual CXB is interpreted as an observational constraint on an earlier stage of AGN evolution. Assuming black hole disk accretion, a picture emerges where young AGNs are compact Eddington limited thermal X-ray sources and where canonical AGNs represent later stages in which they have become appreciably less compact, exhibiting the importance of nonthermal disk-dynamo processes.

Subacromial bursitis following human papilloma virus vaccine misinjection.

PubMed

Uchida, Soshi; Sakai, Akinori; Nakamura, Toshitaka

2012-12-17

A patient presented at our clinic with severe subacromial bursitis, which persisted for several months following a third booster injection with Cervarix™. Chronic subacromial bursitis manifested itself in this patient after what appeared to be the misinjection of vaccine in close proximity to the acromion. This bursitis was resistant to conventional physiotherapy and to corticosteroid therapy, but was responsive to arthroscopic surgery. Since such patients may present to an arthroscopic surgeon only months after receiving a vaccine injection, this etiological link may not be fully appreciated by treating clinicians. Further, the accuracy of injection in the deltoid region also appears under appreciated, and this report highlights the importance of accurate injection to the deltoid region or in certain cases, the value of simply changing the injection site to another larger muscle. Copyright © 2012 Elsevier Ltd. All rights reserved.

[A cyborg is only human].

PubMed

Schermer, Maartje H N

2013-01-01

New biomedical technologies make it possible to replace parts of the human body or to substitute its functions. Examples include artificial joints, eye lenses and arterial stents. Newer technologies use electronics and software, for example in brain-computer interfaces such as retinal implants and the exoskeleton MindWalker. Gradually we are creating cyborgs: hybrids of man and machine. This raises the question: are cyborgs still humans? It is argued that they are. First, because employing technology is a typically human characteristic. Second, because in western thought the human mind, and not the body, is considered to be the seat of personhood. However, it has been argued by phenomenological philosophers that the body is more than just an object but is also a subject, important for human identity. From this perspective, we can appreciate that a bionic body does not make one less human, but it does influence the experience of being human.

Whole-body vibration training induces hypertrophy of the human patellar tendon.

PubMed

Rieder, F; Wiesinger, H-P; Kösters, A; Müller, E; Seynnes, O R

2016-08-01

Animal studies suggest that regular exposure to whole-body vibration (WBV) induces an anabolic response in bone and tendon. However, the effects of this type of intervention on human tendon properties and its influence on the muscle-tendon unit function have never been investigated. The aim of this study was to investigate the effect of WBV training on the patellar tendon mechanical, material and morphological properties, the quadriceps muscle architecture and the knee extension torque-angle relationship. Fifty-five subjects were randomized into either a vibration, an active control, or an inactive control group. The active control subjects performed isometric squats on a vibration platform without vibration. Muscle and tendon properties were measured using ultrasonography and dynamometry. Vibration training induced an increase in proximal (6.3%) and mean (3.8%) tendon cross-sectional area, without any appreciable change in tendon stiffness and modulus or in muscle architectural parameters. Isometric torque at a knee angle of 90° increased in active controls (6.7%) only and the torque-angle relation remained globally unchanged in all groups. The present protocol did not appreciably alter knee extension torque production or the musculo-tendinous parameters underpinning this function. Nonetheless, this study shows for the first time that WBV elicits tendon hypertrophy in humans. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Studies on `allergoids' prepared from naturally occurring allergens

PubMed Central

Marsh, D. G.; Lichtenstein, L. M.; Campbell, D. H.

1970-01-01

The highly purified major allergenic component of rye grass pollen (Group I) was used to investigate the possibility of destroying selectively the allergenic properties of an antigen, while largely retaining its original immunizing capacities. The allergen was treated under mild conditions with formalin alone or formalin plus a reactive low molecular weight additive. Certain derivatives (allergoids) showed well over 99 per cent reduction in allergenicity, determined by the histamine released from allergic human leucocytes in vitro, but were still able to combine with rabbit antibody against native antigen. Furthermore, the allergoids stimulated production (in guinea-pigs) of appreciable amounts of antibody able to inhibit native allergen-mediated human allergic histamine release in vitro and to cross-react with native antigen by PCA tests in normal guinea-pigs. Residual allergenicity and cross-immunogenicity (by the inhibition assay) of the different formalinized derivatives varied appreciably according to the additive used in formalinization, but the cross-reactivities of the different preparations in quantitative precipitin analysis against rabbit anti-native antigen serum were similar. The residual allergenicities of individual derivatives varied by up to 1000-fold in different cell preparations, suggesting a heterogeneity of allergenic determinants. Allergoid derivatives showed no hapten-like activity in that they were unable to inhibit allergen-mediated histamine release from leucocytes. The theoretical and practical application of allergoids is discussed, including their potential usefulness in improving the immunotheraphy of atopic humans. ImagesFIG. 2 PMID:4192674

Introducing Astrophysics and Cosmology as Part of Multidisciplinary Approaches to Liberal Arts Courses Addressing "The Big Questions" of Human Experience

NASA Astrophysics Data System (ADS)

Wesney, J. C.

2012-08-01

There is an opportunity to bring college students to the exploration of the grandeur and wonder of the universe through the design and crafting of courses for the university and liberal arts curricula that would develop multidisciplinary perspectives within the frames of reference of astrophysics and cosmology. There is broad interest within colleges and universities to provide courses that examine "The Big Questions" of human experience from a variety of perspectives. The study of the history of discoveries and insights that we have gained through the development of astrophysics and cosmology provides course options for students to use to explore these questions. Such hybrid courses enable students to approach the questions of origins, human existence, appreciation of the natural world, appreciation of the universe at large, and the significance of our evolving comprehension of the universe from a variety of disciplinary perspectives, including those that border on the astrophysical and cosmological domains. There are within such courses opportunities to examine historical, philosophical, theological, and cultural perspectives as they intersect with our scientific understanding of where and who we are. The first of these courses at Sacred Heart University has been developed and presented for the past two years as part of the new Core Curriculum. The development of that course, entitled The Journey in the Physical Universe, will be discussed, and insights will be shared.

Extended artistic appreciation.

PubMed

Wilson, Robert A

2013-04-01

I propose that in at least some cases, objects of artistic appreciation are best thought of not simply as causes of artistic appreciation, but as parts of the cognitive machinery that drives aesthetic appreciation. In effect, this is to say that aesthetic appreciation operates via extended cognitive systems.

Humour experience in schizophrenia: relationship with executive dysfunction and psychosocial impairment.

PubMed

Tsoi, D T-Y; Lee, K-H; Gee, K A; Holden, K L; Parks, R W; Woodruff, P W R

2008-06-01

The ability to appreciate humour is essential to successful human interactions. In this study, we hypothesized that individuals with schizophrenia would have diminished ability to recognize and appreciate humour. The relationship between humour experience and clinical symptoms, cognitive and social functioning was examined. Thirty patients with a DSM-IV diagnosis of schizophrenia were compared with 30 age-, gender-, IQ- and ethnicity-matched healthy controls. Humour recognition was measured by identification of humorous moments in four silent slapstick comedy film clips and calculated as d-prime (d') according to signal detection theory. Humour appreciation was measured by self-report mood state and funniness ratings. Patients were assessed for clinical symptoms, theory of mind ability, executive function [using the Wisconsin Card Sorting Test (WCST)] and social functioning [using the Life Skills Profile (LSP)]. Patient and control groups did not differ in the funniness ratings they attributed to the video clips. Patients with schizophrenia had a lower d' (humour) compared to the controls, after controlling for (1) the performance of a baseline recognition task with a non-humorous video clip and (2) severity of depressive symptoms. In patients, d' (humour) had significant negative correlation with delusion and depression scores, the perseverative error score of the WCST and the total scores of the LSP. Compared with controls, patients with schizophrenia were less sensitive at detecting humour but similarly able to appreciate humour. The degree of humour recognition difficulty may be associated with the extent of executive dysfunction and thus contribute to the psychosocial impairment in patients with schizophrenia.

Connecting Students with the Human Dimensions in Literature: Using Bruner's Modes of Thought to Deepen Literary Appreciation

ERIC Educational Resources Information Center

McConn, Matthew

2014-01-01

Many times students are directed to make a personal connection to literature without being guided toward how their connection works interdependently with the structure of the narrative to create a greater meaning, much less directed toward how this connection can hold meaning for their own lives. Through student samples, this article attempts to…

Field Work in Ecology for Secondary Schools in Tropical Countries. Science and Technology Education Document Series No. 30.

ERIC Educational Resources Information Center

Kelly, P. J., Ed.

One of the important aims of good biology teaching should be to encourage some basic understanding and appreciation of ecology. This understanding should include not only the scientific basis of ecology, but also its application for human welfare and, in particular, for rational exploitation and management of the natural environment and resources.…

Education for a Culture of Peace in a Gender Perspective.

ERIC Educational Resources Information Center

Reardon, Betty A.

The goal of this study unit on education for a culture of peace in a gender perspective is to assist teachers in their efforts to educate caring and responsible citizens, open to other cultures, able to appreciate the value of freedom, respectful of human dignity and differences, and able to prevent conflicts or resolve them by nonviolent means.…

Does Spatial Ability Help the Learning of Anatomy in a Biomedical Science Course?

ERIC Educational Resources Information Center

Sweeney, Kevin; Hayes, Jennifer A.; Chiavaroli, Neville

2014-01-01

A three-dimensional appreciation of the human body is the cornerstone of clinical anatomy. Spatial ability has previously been found to be associated with students' ability to learn anatomy and their examination performance. The teaching of anatomy has been the subject of major change over the last two decades with the reduction in time spent…

Human Population. (Student Resource Book IV in the Investigating Your Environemnt Program).

ERIC Educational Resources Information Center

Biological Sciences Curriculum Study, Boulder, CO.

These resource papers encourage the student to discover for himself the contributions to a problem made through original literature. Since some of the papers are controversial or contradict one another, the student will need to evaluate them to determine his position. It is hoped that these papers will foster an appreciation of the work of the…

Tracking Our Progress: A Global Monitoring and Evaluation Framework for the UN DESD

ERIC Educational Resources Information Center

Tilbury, Daniella

2009-01-01

The sustainability agenda is a concern of several UN agencies that appreciate how well-being, social justice, human development and the health of our planet are inextricably linked. This remit underpinned the launch of the UN Decade in Education for Sustainable Development (DESD) in 2005. As the DESD reaches its mid-point, mechanisms for assessing…

Health Education in Practice. Taking the Quilt to the Classroom: A Lesson about the Names Project AIDS Memorial Quilt.

ERIC Educational Resources Information Center

Voss, Victoria; Frauenknecht, Marianne

1996-01-01

Presents ideas for a lesson that allows elementary and secondary students to experience an iconic representation of the Names Project AIDS Memorial Quilt in the classroom. By visualizing the quilt exhibit through pictures of individual panels, students can develop a greater appreciation of the human toll taken by the AIDS epidemic. (SM)

Looking Homeward Toward Earth: The Power of Perspective

NASA Astrophysics Data System (ADS)

Abdalati, W.

2012-08-01

With the 1968 "Earthrise" image of planet Earth emerging from beyond the lunar horizon, society's view of our celestial home was changed forever. Beautiful and vulnerable, and suspended in dark stillness, this image inspired an appreciation that we are one human race, whose fate hinges delicately on our collective actions. Since that time, space-based observations of the Earth have continued to provide essential insights and information across the full spectrum of human activities and natural processes, and have even become a mainstream part of our daily lives. From documenting disappearing Arctic ice cover, to providing key insights to hurricane evolution, to tracking the amount of movement and cycles of Earth's biomass, these observations allow us to understand how and why our world is changing, and what these changes mean for life on Earth. But beyond their tremendous scientific value, they can be a powerful and inspiring tool for generating a true appreciation of the complexities and beauty of the world in which we live. From that iconic Earthrise photograph to the viral popularity of event-based satellite imagery, the power of the space-based perspective satisfies our need for constant and current information, and fuels our emotional connection to the planet we call home.

Sex differences during humor appreciation in child-sibling pairs.

PubMed

Vrticka, Pascal; Neely, Michelle; Walter Shelly, Elizabeth; Black, Jessica M; Reiss, Allan L

2013-01-01

The developmental origin of sex differences in adult brain function is poorly understood. Elucidating neural mechanisms underlying comparable cognitive functionality in both children and adults is required to address this gap. Humor appreciation represents a particularly relevant target for such developmental research because explanatory theories apply across the life span, and underlying neurocircuitry shows sex differences in adults. As a positive mood state, humor is also of interest due to sex differences in rates of depression, a disorder afflicting twice as many women as men. In this study, we employed functional magnetic resonance imaging (fMRI) to investigate brain responses to funny versus positive (and neutral) video clips in 22 children, ages 6-13 years, including eight sibling-pairs. Our data revealed increased activity to funny clips in bilateral temporo-occipital cortex, midbrain, and amygdala in girls. Conversely, we found heightened activation to positive clips in bilateral inferior parietal lobule, fusiform gyrus, inferior frontal gyrus, amygdala, and ventromedial prefrontal cortex in boys. Many of these effects persisted when looking at sibling-pairs only. We interpret such findings as reflecting the presence of early sex divergence in reward saliency or expectation and stimulus relevance attribution. These findings are discussed in the context of evolutionary and developmental theories of humor function.

Electrodiagnosis and nerve conduction studies.

PubMed

Posuniak, E A

1984-08-01

The use of electrodiagnostic techniques in evaluation of complaints in the lower extremities provides an objective method of assessment. A basic understanding of principles of neurophysiology, EMG and NCV methodology, and neuropathology of peripheral nerves greatly enhances physical diagnosis and improves the state of the art in treatment of the lower extremity, especially foot and ankle injuries. Familiarity with the method of reporting electrodiagnostic studies and appreciation of the electromyographer's interpretation of the EMG/NCV studies also reflects an enhanced fund of knowledge, skills, and attitudes as pertains to one's level of professional expertise. Information regarding the etiology of positive sharp waves, fibrillation potentials, fasciculation, and normal motor action potentials and conduction studies serves as a sound basis for the appreciation of the categories of nerve injury. Competence in understanding the degree of axonal or myelin function or dysfunction in a nerve improve one's effectiveness not only in medical/surgical treatment but in prognostication of recovery of function. A review of the entrapment syndromes in the lower extremity with emphasis on tarsal tunnel syndrome summarizes the most common nerve entrapments germane to the practice of podiatry. With regard to tarsal tunnel syndrome, the earliest electrodiagnostic study to suggest compression was reported to be the EMG of the foot and leg muscles, even before prolonged nerve latency was noted.

SEX DIFFERENCES DURING HUMOR APPRECIATION IN CHILD SIBLING-PAIRS

PubMed Central

Vrticka, Pascal; Neely, Michelle; Walter, Elizabeth; Black, Jessica M.; Reiss, Allan L.

2013-01-01

The developmental origin of sex differences in adult brain function is poorly understood. Elucidating neural mechanisms underlying comparable cognitive functionality in both children and adults is required to address this gap. Humor appreciation represents a particularly relevant target for such developmental research because explanatory theories apply across the life span and underlying neurocircuitry shows sex differences in adults. As a positive mood state, humor is also of interest due to sex differences in rates of depression, a disorder afflicting twice as many women as men. In this study, we employed fMRI to investigate brain responses to funny versus positive (and neutral) video clips in 22 children ages 6 to 13 years, including 8 sibling pairs. Our data revealed increased activity to funny clips in bilateral temporo-occipital cortex, midbrain, and amygdala in girls. Conversely, we found heightened activation to positive clips in bilateral inferior parietal lobule, fusiform gyrus, inferior frontal gyrus, amygdala, and ventromedial prefrontal cortex in boys. Many of these effects persisted when looking at sibling-pairs only. We interpret such findings as reflecting the presence of early sex divergence in reward saliency / expectation and stimulus relevance attribution. These findings are discussed in the context of evolutionary and developmental theories of humor function. PMID:23672302

Amygdala Response to Emotional Stimuli without Awareness: Facts and Interpretations

PubMed Central

Diano, Matteo; Celeghin, Alessia; Bagnis, Arianna; Tamietto, Marco

2017-01-01

Over the past two decades, evidence has accumulated that the human amygdala exerts some of its functions also when the observer is not aware of the content, or even presence, of the triggering emotional stimulus. Nevertheless, there is as of yet no consensus on the limits and conditions that affect the extent of amygdala’s response without focused attention or awareness. Here we review past and recent studies on this subject, examining neuroimaging literature on healthy participants as well as brain-damaged patients, and we comment on their strengths and limits. We propose a theoretical distinction between processes involved in attentional unawareness, wherein the stimulus is potentially accessible to enter visual awareness but fails to do so because attention is diverted, and in sensory unawareness, wherein the stimulus fails to enter awareness because its normal processing in the visual cortex is suppressed. We argue this distinction, along with data sampling amygdala responses with high temporal resolution, helps to appreciate the multiplicity of functional and anatomical mechanisms centered on the amygdala and supporting its role in non-conscious emotion processing. Separate, but interacting, networks relay visual information to the amygdala exploiting different computational properties of subcortical and cortical routes, thereby supporting amygdala functions at different stages of emotion processing. This view reconciles some apparent contradictions in the literature, as well as seemingly contrasting proposals, such as the dual stage and the dual route model. We conclude that evidence in favor of the amygdala response without awareness is solid, albeit this response originates from different functional mechanisms and is driven by more complex neural networks than commonly assumed. Acknowledging the complexity of such mechanisms can foster new insights on the varieties of amygdala functions without awareness and their impact on human behavior. PMID:28119645

Cytosolic proteins can exploit membrane localization to trigger functional assembly

PubMed Central

2018-01-01

Cell division, endocytosis, and viral budding would not function without the localization and assembly of protein complexes on membranes. What is poorly appreciated, however, is that by localizing to membranes, proteins search in a reduced space that effectively drives up concentration. Here we derive an accurate and practical analytical theory to quantify the significance of this dimensionality reduction in regulating protein assembly on membranes. We define a simple metric, an effective equilibrium constant, that allows for quantitative comparison of protein-protein interactions with and without membrane present. To test the importance of membrane localization for driving protein assembly, we collected the protein-protein and protein-lipid affinities, protein and lipid concentrations, and volume-to-surface-area ratios for 46 interactions between 37 membrane-targeting proteins in human and yeast cells. We find that many of the protein-protein interactions between pairs of proteins involved in clathrin-mediated endocytosis in human and yeast cells can experience enormous increases in effective protein-protein affinity (10–1000 fold) due to membrane localization. Localization of binding partners thus triggers robust protein complexation, suggesting that it can play an important role in controlling the timing of endocytic protein coat formation. Our analysis shows that several other proteins involved in membrane remodeling at various organelles have similar potential to exploit localization. The theory highlights the master role of phosphoinositide lipid concentration, the volume-to-surface-area ratio, and the ratio of 3D to 2D equilibrium constants in triggering (or preventing) constitutive assembly on membranes. Our simple model provides a novel quantitative framework for interpreting or designing in vitro experiments of protein complexation influenced by membrane binding. PMID:29505559

Thinking about Thinking and Emotion: The Metacognitive Approach to the Medical Humanities that Integrates the Humanities with the Basic and Clinical Sciences

PubMed Central

Eichbaum, Quentin G

2014-01-01

Medical knowledge in recent decades has grown prodigiously and has outstripped the capacity of the human brain to absorb and understand it all. This burgeoning of knowledge has created a dilemma for medical educators. We can no longer expect students to continue memorizing this large body of increasingly complex knowledge. Instead, our efforts should be redirected at developing in students a competency as flexible thinkers and agile learners so they can adeptly deal with new knowledge, complexity, and uncertainty in a rapidly changing world. Such a competency would entail not only cognitive but also emotional skills essential for the holistic development of their professional identity. This article will argue that metacognition—“thinking about thinking (and emotion)”—offers the most viable path toward developing this competency. The overwhelming volume of medical knowledge has driven some medical schools to reduce the time allocated in their curricula to the “soft-option” humanities as they tend to consider them an expendable “luxury.” Vanderbilt University School of Medicine, Nashville, TN, has moved away from the traditional conception of the medical humanities as “the arts,” composed of art, music, and literature, toward an approach that integrates the humanities with the basic and clinical sciences, based on metacognition. This metacognitive approach to the humanities, described in this article, has three goals: 1) to develop students as flexible thinkers and agile learners and to provide them with essential cognitive and emotional skills for navigating medical complexity and uncertainty; 2) to elicit in students empathy and tolerance by making them aware of the immense diversity in human cognition (and emotion); and 3) to integrate the humanities with the basic and clinical sciences. Through this metacognitive approach, students come to understand their patterns of cognition and emotions, and in the group setting, they learn to mindfully calibrate their thinking and emotions. They gain a humbling appreciation of the fallibility of the human mind/brain and how cognitive biases and misperceptions can lead to medical error. They come to appreciate the complex interplay between cognition and emotion, and the importance of cognitive monitoring and emotional regulation. In the group setting, students also gain a sense of perspective of their thinking patterns and emotions in relation to those of their peers. Perspective taking and mindfulness engender tolerance and empathy, which ultimately serves as a platform for working collaboratively in teams as medical professionals. Students become aware of the social context in which thinking and learning occur, and this further shapes their professional identity. Thinking, learning, and interacting in the group setting ultimately induces a shift from self-preoccupation and an individualistic approach to knowledge toward an appreciation of collective cognition and empathy towards others. In this article, I describe the metacognitive approach to the medical humanities at Vanderbilt University School of Medicine and how it is designed to develop students as agile learners and flexible thinkers with the mindful capacity for cognitive and emotional monitoring and regulation. Thinking and learning in the group setting of the colloquium ultimately also fosters the student’s professional identity. PMID:25662528

Thinking about thinking and emotion: the metacognitive approach to the medical humanities that integrates the humanities with the basic and clinical sciences.

PubMed

Eichbaum, Quentin G

2014-01-01

Medical knowledge in recent decades has grown prodigiously and has outstripped the capacity of the human brain to absorb and understand it all. This burgeoning of knowledge has created a dilemma for medical educators. We can no longer expect students to continue memorizing this large body of increasingly complex knowledge. Instead, our efforts should be redirected at developing in students a competency as flexible thinkers and agile learners so they can adeptly deal with new knowledge, complexity, and uncertainty in a rapidly changing world. Such a competency would entail not only cognitive but also emotional skills essential for the holistic development of their professional identity. This article will argue that metacognition--“thinking about thinking (and emotion)”--offers the most viable path toward developing this competency. The overwhelming volume of medical knowledge has driven some medical schools to reduce the time allocated in their curricula to the “soft-option” humanities as they tend to consider them an expendable “luxury.” Vanderbilt University School of Medicine, Nashville, TN, has moved away from the traditional conception of the medical humanities as “the arts,” composed of art, music, and literature, toward an approach that integrates the humanities with the basic and clinical sciences, based on metacognition. This metacognitive approach to the humanities, described in this article, has three goals: 1) to develop students as flexible thinkers and agile learners and to provide them with essential cognitive and emotional skills for navigating medical complexity and uncertainty; 2) to elicit in students empathy and tolerance by making them aware of the immense diversity in human cognition (and emotion); and 3) to integrate the humanities with the basic and clinical sciences. Through this metacognitive approach, students come to understand their patterns of cognition and emotions, and in the group setting, they learn to mindfully calibrate their thinking and emotions. They gain a humbling appreciation of the fallibility of the human mind/brain and how cognitive biases and misperception can lead to medical error. They come to appreciate the complex interplay between cognition and emotion, and the importance of cognitive monitoring and emotional regulation. In the group setting, students also gain a sense of perspective of their thinking patterns and emotions in relation to those of their peers. Perspective taking and mindfulness engender tolerance and empathy, which ultimately serves as a platform for working collaboratively in teams as medical professionals. Students become aware of the social context in which thinking and learning occur, and this further shapes their professional identity. Thinking, learning, and interacting in the group setting ultimately induces a shift from self-preoccupation and an individualistic approach to knowledge toward an appreciation of collective cognition and empathy towards others. In this article, I describe the metacognitive approach to the medical humanities at Vanderbilt University School of Medicine and how it is designed to develop students as agile learners and flexible thinkers with the mindful capacity for cognitive and emotional monitoring and regulation. Thinking and learning in the group setting of the colloquium ultimately also fosters the student’s professional identity.

21 CFR 130.3 - Definitions and interpretations.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Definitions and interpretations. 130.3 Section 130.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION FOOD STANDARDS: GENERAL General Provisions § 130.3 Definitions and...

21 CFR 130.3 - Definitions and interpretations.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Definitions and interpretations. 130.3 Section 130.3 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION FOOD STANDARDS: GENERAL General Provisions § 130.3 Definitions and...

The field of medical anthropology in Social Science & Medicine.

PubMed

Panter-Brick, Catherine; Eggerman, Mark

2018-01-01

Conceptually and methodologically, medical anthropology is well-positioned to support a "big-tent" research agenda on health and society. It fosters approaches to social and structural models of health and wellbeing in ways that are critically reflective, cross-cultural, people-centered, and transdisciplinary. In this review article, we showcase these four main characteristics of the field, as featured in Social Science & Medicine over the last fifty years, highlighting their relevance for an international and interdisciplinary readership. First, the practice of critical inquiry in ethnographies of health offers a deep appreciation of sociocultural viewpoints when recording and interpreting lived experiences and contested social worlds. Second, medical anthropology champions cross-cultural breadth: it makes explicit local understandings of health experiences across different settings, using a fine-grained, comparative approach to develop a stronger global platform for the analysis of health-related concerns. Third, in offering people-centered views of the world, anthropology extends the reach of critical enquiry to the lived experiences of hard-to-reach population groups, their structural vulnerabilities, and social agency. Finally, in developing research at the nexus of cultures, societies, biologies, and health, medical anthropologists generate new, transdisciplinary conversations on the body, mind, person, community, environment, prevention, and therapy. As featured in this journal, scholarly contributions in medical anthropology seek to debate human health and wellbeing from many angles, pushing forward methodology, social theory, and health-related practice. Copyright © 2017 Elsevier Ltd. All rights reserved.

Colloquium paper: three ambitious (and rather unorthodox) assignments for the field of biodiversity genetics.

PubMed

Avise, John C

2008-08-12

The field of molecular genetics has many roles in biodiversity assessment and conservation. I summarize three of those standard roles and propose logical extensions of each. First, many biologists suppose that a comprehensive picture of the Tree of Life will soon emerge from multilocus DNA sequence data interpreted in concert with fossils and other evidence. If nonreticulate trees are indeed valid metaphors for life's history, then a well dated global phylogeny will offer an opportunity to erect a universally standardized scheme of biological classification. If life's history proves to be somewhat reticulate, a web-like phylogenetic pattern should become evident and will offer opportunities to reevaluate the fundamental nature of evolutionary processes. Second, extensive networks of wildlife sanctuaries offer some hope for shepherding appreciable biodiversity through the ongoing extinction crisis, and molecular genetics can assist in park design by helping to identify key species, historically important biotic areas, and biodiversity hotspots. An opportunity centers on the concept of Pleistocene Parks that could protect "legacy biotas" in much the same way that traditional national parks preserve special geological features and historical landmarks honor legacy events in human affairs. Third, genetic perspectives have become an integral part of many focused conservation efforts by unveiling ecological, behavioral, or evolutionary phenomena relevant to population management. They also can open opportunities to educate the public about the many intellectual gifts and aesthetic marvels of the natural world.

Three ambitious (and rather unorthodox) assignments for the field of biodiversity genetics

PubMed Central

Avise, John C.

2008-01-01

The field of molecular genetics has many roles in biodiversity assessment and conservation. I summarize three of those standard roles and propose logical extensions of each. First, many biologists suppose that a comprehensive picture of the Tree of Life will soon emerge from multilocus DNA sequence data interpreted in concert with fossils and other evidence. If nonreticulate trees are indeed valid metaphors for life's history, then a well dated global phylogeny will offer an opportunity to erect a universally standardized scheme of biological classification. If life's history proves to be somewhat reticulate, a web-like phylogenetic pattern should become evident and will offer opportunities to reevaluate the fundamental nature of evolutionary processes. Second, extensive networks of wildlife sanctuaries offer some hope for shepherding appreciable biodiversity through the ongoing extinction crisis, and molecular genetics can assist in park design by helping to identify key species, historically important biotic areas, and biodiversity hotspots. An opportunity centers on the concept of Pleistocene Parks that could protect “legacy biotas” in much the same way that traditional national parks preserve special geological features and historical landmarks honor legacy events in human affairs. Third, genetic perspectives have become an integral part of many focused conservation efforts by unveiling ecological, behavioral, or evolutionary phenomena relevant to population management. They also can open opportunities to educate the public about the many intellectual gifts and aesthetic marvels of the natural world. PMID:18695224

TRACING CO-REGULATORY NETWORK DYNAMICS IN NOISY, SINGLE-CELL TRANSCRIPTOME TRAJECTORIES.

PubMed

Cordero, Pablo; Stuart, Joshua M

2017-01-01

The availability of gene expression data at the single cell level makes it possible to probe the molecular underpinnings of complex biological processes such as differentiation and oncogenesis. Promising new methods have emerged for reconstructing a progression 'trajectory' from static single-cell transcriptome measurements. However, it remains unclear how to adequately model the appreciable level of noise in these data to elucidate gene regulatory network rewiring. Here, we present a framework called Single Cell Inference of MorphIng Trajectories and their Associated Regulation (SCIMITAR) that infers progressions from static single-cell transcriptomes by employing a continuous parametrization of Gaussian mixtures in high-dimensional curves. SCIMITAR yields rich models from the data that highlight genes with expression and co-expression patterns that are associated with the inferred progression. Further, SCIMITAR extracts regulatory states from the implicated trajectory-evolvingco-expression networks. We benchmark the method on simulated data to show that it yields accurate cell ordering and gene network inferences. Applied to the interpretation of a single-cell human fetal neuron dataset, SCIMITAR finds progression-associated genes in cornerstone neural differentiation pathways missed by standard differential expression tests. Finally, by leveraging the rewiring of gene-gene co-expression relations across the progression, the method reveals the rise and fall of co-regulatory states and trajectory-dependent gene modules. These analyses implicate new transcription factors in neural differentiation including putative co-factors for the multi-functional NFAT pathway.

42 CFR 37.50 - Interpreting and classifying chest radiographs-film.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Interpreting and classifying chest radiographs-film. 37.50 Section 37.50 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Interpreting and classifying chest radiographs—film. (a) Chest radiographs must be interpreted and classified...

Jekyll and Hyde revisited: paradoxes in the appreciation of drug experiences and their effects on creativity.

PubMed

ten Berge, Jos

2002-01-01

Historically, states of intoxication--like dreams and madness--are seen in either one of two opposed ways. The intoxicated are either "possessed" or "under the influence" of an external agency, or revealing hidden feelings or truths (in vino veritas). Along the same lines, artists who worked during LSD, mescalin or psilocybin intoxication often refer to feelings of either being "possessed" or "liberated," a difference that can be explained partly by their expectations and partly by their evaluations, which both tend to conform to the cultural dichotomy in interpreting the irrational. Both interpretations, however, tend to obscure not only the other, but also-it is posited-the paradoxical nature of the drug experience itself. Analysis of a protocol shows that intoxication might comprise feelings of "possession" as well as "liberation" almost simultaneously, and mediumistic and some psychedelic art shows stylistic traits that can be seen as the visual expressions of both these feelings. It seems that the "demoniacal" and "psychedelic" mode come together in experiential reality, only to be divided in the cultural sphere.

Testing hypotheses and the advancement of science: recent attempts to falsify the equilibrium point hypothesis.

PubMed

Feldman, Anatol G; Latash, Mark L

2005-02-01

Criticisms of the equilibrium point (EP) hypothesis have recently appeared that are based on misunderstandings of some of its central notions. Starting from such interpretations of the hypothesis, incorrect predictions are made and tested. When the incorrect predictions prove false, the hypothesis is claimed to be falsified. In particular, the hypothesis has been rejected based on the wrong assumptions that it conflicts with empirically defined joint stiffness values or that it is incompatible with violations of equifinality under certain velocity-dependent perturbations. Typically, such attempts use notions describing the control of movements of artificial systems in place of physiologically relevant ones. While appreciating constructive criticisms of the EP hypothesis, we feel that incorrect interpretations have to be clarified by reiterating what the EP hypothesis does and does not predict. We conclude that the recent claims of falsifying the EP hypothesis and the calls for its replacement by EMG-force control hypothesis are unsubstantiated. The EP hypothesis goes far beyond the EMG-force control view. In particular, the former offers a resolution for the famous posture-movement paradox while the latter fails to resolve it.

The role of physics in shaping music

NASA Astrophysics Data System (ADS)

Townsend, Peter

2015-07-01

Physics and technology have played a major role in shaping the development, performance, interpretation and composition of music for many centuries. From the twentieth century, electronics and communications have provided recording and broadcasting that gives access to worldwide music and performers of many musical genres. Early scientific influence came via improved or totally new instruments, plus larger and better concert halls. Instrument examples range from developments of violins or pianos to keyed and valved wood wind and brass that offer chromatic performance. New sounds appeared by inventions of totally new instruments, such as the saxophone or the Theremin, to all the modern electronic influence on keyboards and synthesisers. Electronic variants of guitars are effectively new instruments that have spawned totally original musical styles. All such advances have encouraged more virtuosic performance, larger halls, a wider range of audiences and a consequent demand and ability of composers to meet the new challenges. Despite this immense impact, the role of physics and technology over the last few centuries has mostly been ignored, although it was often greater than any links to arts or culture. Recorded and broadcast music has enhanced our expectations on performance and opened gateways to purely electronically generated sounds, of the now familiar electronic keyboards and synthesisers. This brief review traces some of the highlights in musical evolution that were enabled by physics and technology and their impact on the musical scene. The pattern from the past is clear, and so some of the probable advances in the very near future are also predicted. Many are significant as they will impinge on our appreciation of both current and past music, as well as compositional styles. Mention is made of the difference in sound between live and recorded music and the reasons why none of us ever have precisely the same musical experience twice, even from the same recording. Similarly, it is impossible to appreciate earlier music from the same perspective as occurred when it was first composed and performed, or indeed from later interpretations.

Conventionalism and Methodological Standards in Contending with Skepticism about Uncertainty

NASA Astrophysics Data System (ADS)

Brumble, K. C.

2012-12-01

What it means to measure and interpret confidence and uncertainty in a result is often particular to a specific scientific community and its methodology of verification. Additionally, methodology in the sciences varies greatly across disciplines and scientific communities. Understanding the accuracy of predictions of a particular science thus depends largely upon having an intimate working knowledge of the methods, standards, and conventions utilized and underpinning discoveries in that scientific field. Thus, valid criticism of scientific predictions and discoveries must be conducted by those who are literate in the field in question: they must have intimate working knowledge of the methods of the particular community and of the particular research under question. The interpretation and acceptance of uncertainty is one such shared, community-based convention. In the philosophy of science, this methodological and community-based way of understanding scientific work is referred to as conventionalism. By applying the conventionalism of historian and philosopher of science Thomas Kuhn to recent attacks upon methods of multi-proxy mean temperature reconstructions, I hope to illuminate how climate skeptics and their adherents fail to appreciate the need for community-based fluency in the methodological standards for understanding uncertainty shared by the wider climate science community. Further, I will flesh out a picture of climate science community standards of evidence and statistical argument following the work of philosopher of science Helen Longino. I will describe how failure to appreciate the conventions of professionalism and standards of evidence accepted in the climate science community results in the application of naïve falsification criteria. Appeal to naïve falsification in turn has allowed scientists outside the standards and conventions of the mainstream climate science community to consider themselves and to be judged by climate skeptics as valid critics of particular statistical reconstructions with naïve and misapplied methodological criticism. Examples will include the skeptical responses to multi-proxy mean temperature reconstructions and congressional hearings criticizing the work of Michael Mann et al.'s Hockey Stick.

Caring presence in practice: facilitating an appreciative discourse in nursing.

PubMed

du Plessis, E

2016-09-01

To report on an appreciation of caring presence practised by nurses in South Africa in order to facilitate an appreciative discourse in nursing and a return to caring values and attitudes. Appreciative reports on caring presence are often overlooked. Media may provide a platform for facilitating appreciation for caring presence practised by nurses. Such an appreciation may foster further practice of caring presence and re-ignite a caring ethos in nursing. This article provides an appreciative discourse on caring presence in nursing in the form of examples of caring presence practised by nurses. An anecdotal approach was followed. Social media, namely narratives on caring presence shared by nurses on a Facebook page, and formal media, namely news reports in which nurses are appreciated for their efforts, were used. Deductive content analysis was applied to analyse the narratives and news reports in relation to a definition of caring presence and types of caring presence. The analysis of the narratives and news reports resulted in an appreciative discourse in which examples of nurses practising caring presence could be provided. Examples of nurses practising caring presence could be found, and an appreciative discourse could be initiated. Appreciation ignites positive action and ownership of high-quality health care. Leadership should thus cultivate a culture of appreciating nurses, through using media, and encourage nurses to share how caring presence impact on quality in health care. © 2016 International Council of Nurses.

From "Forest Fires" and "Hunting" to Disturbing "Habitats" and "Food Chains": Do Young Children Come Up with Any Ecological Interpretations of Human Interventions within a Forest?

ERIC Educational Resources Information Center

Ergazaki, Marida; Andriotou, Eirini

2010-01-01

This study aims at highlighting young children's reasoning about human interventions within a forest ecosystem. Our focus is particularly set on whether preschoolers are able to come up with any basic ecological interpretations of human actions upon forest plants or animals and how. Conducting individual, semi-structured interviews with 70…

Subunit dissociation in fish hemoglobins.

PubMed

Edelstein, S J; McEwen, B; Gibson, Q H

1976-12-10

The tetramer-dimer dissociation equilibria (K 4,2) of several fish hemoglobins have been examined by sedimentation velocity measurements with a scanner-computer system for the ultracentrifuge and by flash photolysis measurements using rapid kinetic methods. Samples studied in detail included hemoglobins from a marine teleost, Brevoortia tyrannus (common name, menhaden); a fresh water teleost, Cyprinus carpio, (common name, carp); and an elasmobranch Prionace glauca (common name, blue shark). For all three species in the CO form at pH 7, in 0.1 M phosphate buffer, sedimentation coefficients of 4.3 S (typical of tetrameric hemoglobin) are observed in the micromolar concentration range. In contrast, mammalian hemoglobins dissociate appreciably to dimers under these conditions. The inability to detect dissociation in three fish hemoglobins at the lowest concentrations examined indicates that K 4,2 must have a value of 10(-8) M or less. In flash photolysis experiments on very dilute solutions in long path length cells, two kinetic components were detected with their proportions varying as expected for an equilibrium between tetramers (the slower component) and dimers (the faster component); values of K 4,2 for the three fish hemoglobins in the range 10(-9) to 10(-8) M were calculated from these data. Thus, the values of K 4,2 for liganded forms of the fish hemoglobins appear to be midway between the value for liganded human hemoglobin (K 4,2 approximately 10(-6) M) and unliganded human hemoglobin (K 4,2 approximately 10(-12) M). This conclusion is supported by measurements on solutions containing guanidine hydrochloride to enhance the degree of dissociation. All three fish hemoglobins are appreciably dissociated at guanidine concentrations of about 0.8 M, which is roughly midway between the guanidine concentrations needed to cause comparable dissociation of liganded human hemoglobin (about 0.4 M) and unliganded human hemoglobin (about 1.6 M). Kinetic measurements on solutions containing guanidine hydrochloride indicated that there are changes in both the absolute rates and the proportions of the fast and slow components, which along with other factors complicated the analysis of the data in terms of dissociation constants. Measurements were also made in solutions containing urea to promote dissociation, but with this agent very high concentrations (about 6 M) were required to give measureable dissociation and the fish hemoglobins were unstable under these conditions, with appreciable loss of absorbance spectra in both the sedimentation and kinetic experiments.

A qualitative study on the attributes of nurses' workplace social capital in Japan.

PubMed

Norikoshi, Kensuke; Kobayashi, Toshio; Tabuchi, Keiji

2018-01-01

To identify attributes of nurses' workplace social capital in Japan. Much attention has been paid to nurses' workplace social capital to improve the quality of the work environment; however, few studies are available on the attributes of nurses' workplace social capital. Semi-structured interviews were conducted with 32 nurses at seven hospitals. Nurses reported on the attributes of workplace social capital, such as characteristics facilitating individual positive action in an organisation, which were qualitatively analysed using the Kawakita Jiro method. The attributes of nurses' workplace social capital were organised into six groups: affirmation; exchange of appreciation; unrestricted information sharing; ability to trust; access to the strength; and altruistic reciprocity. The attributes of nurses' workplace social capital included a social structure that allowed nurses to make full use of their abilities both vertically and horizontally and were supported by a sense of security. In particular, newly emerged exchange of appreciation and altruistic reciprocity were important for nurses in Japan in building cooperative relationships with others. Managing human relationships, such as exchange of appreciation and altruistic reciprocity, in clinical settings based on nurses' workplace social capital may promote positive emotions in the organisation, positive ideas among staff and cooperative teamwork, which may lead to high-quality patient care. © 2017 John Wiley & Sons Ltd.

[A "dialogue" between the aesthetics of nursing and philosophy].

PubMed

Chang, Chia-Hsiu; Chen, Chung-Hey

2012-02-01

Nursing aesthetics belong to the broader school of aesthetics, a branch of philosophy, as well as the nursing arts, an element of professional nursing. The philosophy of aesthetics recognizes the connection between an author and appreciators and identifies both substantive and abstract aesthetic experiences in interpersonal communication through the fine arts. Nursing aesthetics values the meaningful moments of patients, is sensitive to the influences of different circumstances and situations, and appreciates the unique qualities of humanness. Nursing aesthetics is emancipatory knowledge and involves empirical, ethical and personal knowing. The article is based on a search of OvidSP and Chinese Electronic Periodical Services (CEPS) database references using key words including aesthetic, aesthetics, art of nursing, or nursing aesthetics as well as a review of books related to aesthetics, knowledge construction, and nursing aesthetics. Authors determined definitions as defined by nursing experts and the applications thereof in clinical practice. This article aimed to illustrate that the ultimate concern of philosophy is "goodness" and that the foundation of caring behaviors is "love". In practice, nursing aesthetics is expressed through empathy, appreciation, inspiration and the therapeutic use of the self. Through aesthetic knowing and enhanced perceptual sensibility and reflection, nurses can transform intuitive knowing into art-acts and ultimately enhance nursing care quality.

Art, energy, and the brain.

PubMed

Pepperell, Robert

2018-01-01

Recent years have seen a growing interest among neuroscientists and vision scientists in art and aesthetics, exemplifying a more general trend toward interdisciplinary integration in the arts, humanities, and sciences. However, true art-science integration remains a distant prospect due to fundamental differences in outlook and approach between disciplines. I consider two great challenges for any project designed to explain the role of the brain in art appreciation. First, scientists and artists need to identify common ground, common questions, and a shared motivation for inquiry. Second, the neuroscience of art must transcend its current goal of correlating brain functions to behavior and begin to explain the connection between activity in the brain and the phenomenology of art appreciation. I propose that both challenges can be tackled using an energy-based approach. The concept of "energy" is clearly of central importance to the physical sciences, and to neuroscience in particular. Meanwhile, energy is a concept that artists and art historians have consistently referred to when trying to articulate how artworks are made and appreciated. I survey the role of energy in art, philosophical and psychological aesthetics, and neuroscience, and suggest how this approach could help to further integrate art and neuroscience, and explain how brain activity contributes to aesthetic experience. © 2018 Elsevier B.V. All rights reserved.

Georg Büchner, Sigmund Freud and the "Schädelnerven" (cranial nerves) - research on the brain and soul in the 19th century.

PubMed

Hildebrandt, Gerhard; Ruppert, Christina; Stienen, Martin N; Surbeck, Werner

2014-10-01

One of the authors' encounter with one of Sigmund Freud's original works about the anatomy of the human brain stem and his interest in the scientist, anatomist, philosopher, writer and revolutionary Georg Büchner led to re-examination and review of the original writings of two major 19th century protagonists of brain anatomy research. The aim of the authors is to highlight the achievements of both Freud and Büchner in the field of comparative brain morphology. The medical and philosophical publications of Georg Büchner were reviewed with reference to the historical-critical edition of his complete works and writings (the so-called Marburg edition). Evaluation of the neuroanatomical achievements of Sigmund Freud was based on a summary of his publications and also partially on his autobiographical writings. After careful review of their publications both Freud and Büchner should be acknowledged as brain scientists focusing particularly on comparative morphology. Both chose fish as the subject of their macroscopic (Büchner) and microscopic (Freud) neuroanatomical studies, and both cut across their own language and cultural space by continuing their work in France. In interpreting their findings both were influenced by their respective contemporary methodological schools of thought. Büchner became a soul scientist/psychologist by turning to the writing of literary texts, heralding the end of his idealistic and metaphysical interpretation of life. Likewise, Freud increasingly devoted himself to the destiny of man and his "conditio humana," eventually turning away from anatomical brain research. Review of the biographies and medical-scientific, as well as philosophical publications, of Georg Büchner and Sigmund Freud reveal striking parallels between the two researchers in addition to common insights that have generally been ignored or only marginally addressed in the past. Both should be appreciated and remembered as forerunners of today's neuroscientific community.

Creating stories for learning about the neonatal care experience through the eyes of student nurses: An interpretive, narrative study.

PubMed

Petty, Julia

2017-01-01

Storytelling is an increasingly well recognised and valued platform to learn about the human experience within healthcare. Little is known however about how stories can enhance understanding in neonatal care, a specialised field offering rich opportunities for learning. This study focuses on the creation of stories based on the experiences of student nurses to inform teaching and learning strategies in the neonatal field. The study aimed to create stories from the narratives of student nurses working within the neonatal field and identify what key themes for learning emerged in order to develop a storytelling resource to share experiences with their peers. An interpretive, constructivist approach was used to collect, analyse and create stories from student nurse's experiences, in line with narrative inquiry. Six pre-registration children's nursing students were selected by purposive sampling. Interviews were undertaken within six weeks following placement completion in an agreed location. Narratives were obtained by semi-structured interviews. Narrative analysis and core story creation was undertaken to construct stories and key learning themes emerged which provided the pedagogical basis for subsequent digital resource development. Key themes emerged relating to the insight and observances of student nurses and the neonatal journey they had experienced, including the nature of neonatal care, experiences of the neonate and parents, the environment and their own learning transition. Preliminary peer evaluation of the storytelling resource revealed storytelling as an interesting and novel approach to teaching & learning, learning from ones' peers, preparation for practice and a valuable insight into a new specialist area. The study has value to teaching and learning by enabling an appreciation of how narrative can be used to portray the experiences of learners. Findings also support an approach to analysing narrative to create stories for learning and inform subsequent digital resource development. Copyright © 2016 Elsevier Ltd. All rights reserved.

Dynamics of aesthetic appreciation

NASA Astrophysics Data System (ADS)

Carbon, Claus-Christian

2012-03-01

Aesthetic appreciation is a complex cognitive processing with inherent aspects of cold as well as hot cognition. Research from the last decades of empirical has shown that evaluations of aesthetic appreciation are highly reliable. Most frequently, facial attractiveness was used as the corner case for investigating aesthetic appreciation. Evaluating facial attractiveness shows indeed high internal consistencies and impressively high inter-rater reliabilities, even across cultures. Although this indicates general and stable mechanisms underlying aesthetic appreciation, it is also obvious that our taste for specific objects changes dynamically. Aesthetic appreciation on artificial object categories, such as fashion, design or art is inherently very dynamic. Gaining insights into the cognitive mechanisms that trigger and enable corresponding changes of aesthetic appreciation is of particular interest for research as this will provide possibilities to modeling aesthetic appreciation for longer durations and from a dynamic perspective. The present paper refers to a recent two-step model ("the dynamical two-step-model of aesthetic appreciation"), dynamically adapting itself, which accounts for typical dynamics of aesthetic appreciation found in different research areas such as art history, philosophy and psychology. The first step assumes singular creative sources creating and establishing innovative material towards which, in a second step, people adapt by integrating it into their visual habits. This inherently leads to dynamic changes of the beholders' aesthetic appreciation.

Music cognition and the cognitive sciences.

PubMed

Pearce, Marcus; Rohrmeier, Martin

2012-10-01

Why should music be of interest to cognitive scientists, and what role does it play in human cognition? We review three factors that make music an important topic for cognitive scientific research. First, music is a universal human trait fulfilling crucial roles in everyday life. Second, music has an important part to play in ontogenetic development and human evolution. Third, appreciating and producing music simultaneously engage many complex perceptual, cognitive, and emotional processes, rendering music an ideal object for studying the mind. We propose an integrated status for music cognition in the Cognitive Sciences and conclude by reviewing challenges and big questions in the field and the way in which these reflect recent developments. Copyright © 2012 Cognitive Science Society, Inc.

Do bees like Van Gogh's Sunflowers?

NASA Astrophysics Data System (ADS)

Chittka, Lars; Walker, Julian

2006-06-01

Flower colours have evolved over 100 million years to address the colour vision of their bee pollinators. In a much more rapid process, cultural (and horticultural) evolution has produced images of flowers that stimulate aesthetic responses in human observers. The colour vision and analysis of visual patterns differ in several respects between humans and bees. Here, a behavioural ecologist and an installation artist present bumblebees with reproductions of paintings highly appreciated in Western society, such as Van Gogh's Sunflowers. We use this unconventional approach in the hope to raise awareness for between-species differences in visual perception, and to provoke thinking about the implications of biology in human aesthetics and the relationship between object representation and its biological connotations.

Brain regions involved in observing and trying to interpret dog behaviour.

PubMed

Desmet, Charlotte; van der Wiel, Alko; Brass, Marcel

2017-01-01

Humans and dogs have interacted for millennia. As a result, humans (and especially dog owners) sometimes try to interpret dog behaviour. While there is extensive research on the brain regions that are involved in mentalizing about other peoples' behaviour, surprisingly little is known of whether we use these same brain regions to mentalize about animal behaviour. In this fMRI study we investigate whether brain regions involved in mentalizing about human behaviour are also engaged when observing dog behaviour. Here we show that these brain regions are more engaged when observing dog behaviour that is difficult to interpret compared to dog behaviour that is easy to interpret. Interestingly, these results were not only obtained when participants were instructed to infer reasons for the behaviour but also when they passively viewed the behaviour, indicating that these brain regions are activated by spontaneous mentalizing processes.

Brain regions involved in observing and trying to interpret dog behaviour

PubMed Central

Desmet, Charlotte; van der Wiel, Alko; Brass, Marcel

2017-01-01

Humans and dogs have interacted for millennia. As a result, humans (and especially dog owners) sometimes try to interpret dog behaviour. While there is extensive research on the brain regions that are involved in mentalizing about other peoples’ behaviour, surprisingly little is known of whether we use these same brain regions to mentalize about animal behaviour. In this fMRI study we investigate whether brain regions involved in mentalizing about human behaviour are also engaged when observing dog behaviour. Here we show that these brain regions are more engaged when observing dog behaviour that is difficult to interpret compared to dog behaviour that is easy to interpret. Interestingly, these results were not only obtained when participants were instructed to infer reasons for the behaviour but also when they passively viewed the behaviour, indicating that these brain regions are activated by spontaneous mentalizing processes. PMID:28931030

Maimonides’ Appreciation for Medicine

PubMed Central

Gesundheit, Benjamin

2011-01-01

Moses Maimonides, the illustrious medieval rabbi and philosopher, dedicated the last decade of his life primarily to medicine. His strong interest in medicine was an integral component of his religious-philosophical teachings and world view. In this paper various sources from his rabbinic writings are presented that explain Maimonides’ motivation regarding and deep appreciation for medicine: (A) The physician fulfills the basic biblical obligation to return lost objects to their owner, for with his knowledge and experience the physician can restore good health to his sick fellow human being; (B) medicine provides a unique opportunity to practice imitatio dei, as it reflects the religious duty to maintain a healthy life-style; (C) as an important natural science, medicine offers tools to recognize, love, and fear God. These three aspects address man’s relationship and obligation towards his fellow-man, himself and God. Biographical insights supported by additional sources from Maimonides’ writings are discussed. PMID:23908790

Job-related motivational factors among Malaysian employees.

PubMed

Manshor, Amat Taap; Abdullah, Adilah

2002-12-01

This study identified job-related motivational factors among Malaysian employees in several telecommunication companies. Responses were obtained from 1,179 employees at all levels up to senior managers and six different functional divisions, sales and marketing, human resources, finance, technical, information, technology, and support division. All employees were asked to rate the importance of Kovach's 10 job-motivational factors. These factors were good wages, job security, opportunity for career growth in the organization, good working conditions, interesting work, company loyalty to employees, tactful discipline, full appreciation of work done, sympathetic help with personal problems, and feeling of being involved in the organization. The top five factors employees identified as motivating them in their jobs were good wages, job security, company loyalty to employees, good working conditions, and full appreciation for work done. Findings were in accordance with Kovach for U.S. employees, in which the top motivational factors were good wages and job security.

'Ease of interpretation' of cytological smears stained with modified ultrafast papanicolaou stain: Interobserver agreement and reproducibility.

PubMed

Uthamalingam, Preithy; Sathish Kumar, Thabasum; Venus, Albina; Sekar, Preethi; Muthusamy, Rajeshwari K; Mehta, Sangita

2018-04-01

Since its inception in 1995, the Ultrafast Papanicoloau (UFPAP) cytological stain has undergone a number of modifications to suit the local availability of reagents and cost in different set ups. However, the reported results have been uniformly encouraging. We designed a study to investigate the inter-observer agreement in 'perceived ease of interpretation' of cytological smears stained with Modified Ultrafast Papanicoloau stain (MUFPAP). After a small pilot study, we prospectively stained air-dried fine needle aspirate smears (FNACs) and Body Fluid smears with the standardized MUFPAP stain. The MUFPAP stained slides were evaluated in tandem with other routine cytological stains as well as independently by two pathologists. Two rater kappa was used to determine the agreement. The study included 93 fluids and 34 FNACs. A vast majority of the cases stained with MUFPAP were rated 'better' than the routine stains in terms of 'overall ease of interpretation' with considerable agreement. The agreement tended to be better for FNACs than fluid specimens. Cases with malignant pathology demonstrated a perfect agreement (kappa = 1) between the raters in terms of 'overall ease of interpretation' (91.7% cases were rated 'very good' by each pathologist) when compared to cases with benign pathology (kappa = 0.52). Nuclear characteristics were appreciated with a better agreement than other parameters. Modified UFPAP stain appears to be quick, reliable, cost-effective alternative in cytology, especially for detecting malignant cells in smears with low cellularity. Its specific advantage is robust nuclear staining against a clear background. © 2018 Wiley Periodicals, Inc.

The Influence of Basic Physical Properties of Soil on its Electrical Resistivity Value under Loose and Dense Condition

NASA Astrophysics Data System (ADS)

Abidin, M. H. Z.; Ahmad, F.; Wijeyesekera, D. C.; Saad, R.

2014-04-01

Electrical resistivity technique has become a famous alternative tool in subsurface characterization. In the past, several interpretations of electrical resistivity results were unable to be delivered in a strong justification due to lack of appreciation of soil mechanics. Traditionally, interpreters will come out with different conclusion which commonly from qualitative point of view thus creating some uncertainty regarding the result reliability. Most engineers desire to apply any techniques in their project which are able to provide some clear justification with strong, reliable and meaningful results. In order to reduce the problem, this study presents the influence of basic physical properties of soil due to the electrical resistivity value under loose and dense condition. Two different conditions of soil embankment model were tested under electrical resistivity test and basic geotechnical test. It was found that the electrical resistivity value (ERV, ρ) was highly influenced by the variations of soil basic physical properties (BPP) with particular reference to moisture content (w), densities (ρbulk/dry), void ratio (e), porosity (η) and particle grain fraction (d) of soil. Strong relationship between ERV and BPP can be clearly presents such as ρ ∞ 1/w, ρ ∞ 1/ρbulk/dry, ρ ∞ e and ρ ∞ η. This study therefore contributes a means of ERV data interpretation using BPP in order to reduce ambiguity of ERV result and interpretation discussed among related persons such as geophysicist, engineers and geologist who applied these electrical resistivity techniques in subsurface profile assessment.

Exploring uncertainty in the Earth Sciences - the potential field perspective

NASA Astrophysics Data System (ADS)

Saltus, R. W.; Blakely, R. J.

2013-12-01

Interpretation of gravity and magnetic anomalies is mathematically non-unique because multiple theoretical solutions are possible. The mathematical label of 'non-uniqueness' can lead to the erroneous impression that no single interpretation is better in a geologic sense than any other. The purpose of this talk is to present a practical perspective on the theoretical non-uniqueness of potential field interpretation in geology. There are multiple ways to approach and constrain potential field studies to produce significant, robust, and definitive results. For example, a smooth, bell-shaped gravity profile, in theory, could be caused by an infinite set of physical density bodies, ranging from a deep, compact, circular source to a shallow, smoothly varying, inverted bell-shaped source. In practice, however, we can use independent geologic or geophysical information to limit the range of possible source densities and rule out many of the theoretical solutions. We can further reduce the theoretical uncertainty by careful attention to subtle anomaly details. For example, short-wavelength anomalies are a well-known and theoretically established characteristic of shallow geologic sources. The 'non-uniqueness' of potential field studies is closely related to the more general topic of scientific uncertainty in the Earth sciences and beyond. Nearly all results in the Earth sciences are subject to significant uncertainty because problems are generally addressed with incomplete and imprecise data. The increasing need to combine results from multiple disciplines into integrated solutions in order to address complex global issues requires special attention to the appreciation and communication of uncertainty in geologic interpretation.

Robotic Navigation Emulating Human Performance

DTIC Science & Technology

2012-03-10

information given”. The special role and significance of shape in visual perception was appreciated and highlighted by the Gestalt Psychologists...denigrate this as well as many other contributions of the Gestalt Psychologists to visual perception . The few who did try to work on it tried to formulate... theories and models of FGO without clarifying the ill-defined concepts used by Gestalt Psychologists before the Cognitive Revolution. This led to a

Holocaust "Laughter" and Edgar Hilsenrath's "The Nazi and the Barber": Towards a Critical Pedagogy of Laughter and Humor in Holocaust Education

ERIC Educational Resources Information Center

Zembylas, Michalinos

2018-01-01

This article tries to defend the position that Holocaust Education can be enriched by appreciating laughter and humor as critical and transformative forces that not only challenge dominant discourses about the Holocaust and its representational limits, but also reclaim humanity, ethics, and difference from new angles and juxtapositions. Edgar…

Education for Social Work Practice with American Indian Families: 2. Instructor's Manual. Child Welfare Training.

ERIC Educational Resources Information Center

Brown, Eddie F.; Shaughnessy, Timothy F.

Learning activities are the main feature of this instructor's guide for a course which emphasizes appreciation of American Indian culture for non-Indian human service providers. The course can be completed in 12-15 hours and may be used as part of a college social work course or presented in workshop fashion. The manual is companion to a student…

Acknowledging and Appreciating the Full Spectrum of the Human Condition: School Psychology's (Limited) Focus on Positive Psychological Functioning

ERIC Educational Resources Information Center

Froh, Jeffrey J.; Huebner, E. Scott; Youssef, Al-Jameela; Conte, Vincent

2011-01-01

This study is a content analysis of a random selection of 20% (N = 1,168) of articles from "School Psychology Quarterly", "Psychology in the Schools", the "Journal of School Psychology", and "School Psychology Review". Across the four journals, 27% of the articles had a positive focus, and the percentage of articles focused on the positive has…

Social Water Science Data: Dimensions, Data Management, and Visualization

NASA Astrophysics Data System (ADS)

Jones, A. S.; Horsburgh, J. S.; Flint, C.; Jackson-Smith, D.

2016-12-01

Water systems are increasingly conceptualized as coupled human-natural systems, with growing emphasis on representing the human element in hydrology. However, social science data and associated considerations may be unfamiliar and intimidating to many hydrologic researchers. Monitoring social aspects of water systems involves expanding the range of data types typically used in hydrology and appreciating nuances in datasets that are well known to social scientists, but less understood by hydrologists. We define social water science data as any information representing the human aspects of a water system. We present a scheme for classifying these data, highlight an array of data types, and illustrate data management considerations and challenges unique to social science data. This classification scheme was applied to datasets generated as part of iUTAH (innovative Urban Transitions and Arid region Hydro-sustainability), an interdisciplinary water research project based in Utah, USA that seeks to integrate and share social and biophysical water science data. As the project deployed cyberinfrastructure for baseline biophysical data, cyberinfrastructure for analogous social science data was necessary. As a particular case of social water science data, we focus in this presentation on social science survey data. These data are often interpreted through the lens of the original researcher and are typically presented to interested parties in static figures or reports. To provide more exploratory and dynamic communication of these data beyond the individual or team who collected the data, we developed a web-based, interactive viewer to visualize social science survey responses. This interface is applicable for examining survey results that show human motivations and actions related to environmental systems and as a useful tool for participatory decision-making. It also serves as an example of how new data sharing and visualization tools can be developed once the classification and characteristics of social water science data are well understood. We demonstrate the survey data viewer implemented to explore water-related survey data collected as part of the iUTAH project. The Viewer uses a standardized template for encoding survey data and metadata, making it generalizable and reusable for similar surveys.

Eld's deer translocated to human-inhabited areas become nocturnal.

PubMed

Pan, Duo; Teng, Liwei; Cui, Fangjie; Zeng, Zhigao; Bravery, Benjamin D; Zhang, Qiong; Song, Yanling

2011-02-01

As human populations expand and nonhuman animals decline, understanding the interactions between people and wildlife is essential. For endangered species, appreciating the effect of human disturbance can be important for their conservation. However, a human disturbance angle is often absent from ecological research, despite growing evidence of the negative impact of nonfatal human interference. Here, we monitored Hainan Eld's deer living within a reserve and translocated animals living amongst villagers. We show that translocated deer deviated from a crepuscular activity pattern and became increas-. ingly nocturnal, and most active when villagers were not. It appears that translocated deer adapted over time to human disturbance and this pattern is similar to that of other species during periods of hunting. People do not pose an actual threat to Eld's deer, but their presence triggered a response akin to predator avoidance and may be interfering with broader aspects of their biology and conservation.

77 FR 33748 - International Conference on Harmonisation; Guidance on S2(R1) Genotoxicity Testing and Data...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-07

... standard genetic toxicology battery for prediction of potential human risks, and on interpreting results... followup testing and interpretation of positive results in vitro and in vivo in the standard genetic... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2008-D-0178...

Conflicting Interpretations of Scientific Pedagogy

NASA Astrophysics Data System (ADS)

Galamba, Arthur

2016-05-01

Not surprisingly historical studies have suggested that there is a distance between concepts of teaching methods, their interpretations and their actual use in the classroom. This issue, however, is not always pitched to the personal level in historical studies, which may provide an alternative insight on how teachers conceptualise and engage with concepts of teaching methods. This article provides a case study on this level of conceptualisation by telling the story of Rómulo de Carvalho, an educator from mid-twentieth century Portugal, who for over 40 years engaged with the heuristic and Socratic methods. The overall argument is that concepts of teaching methods are open to different interpretations and are conceptualised within the melting pot of external social pressures and personal teaching preferences. The practice and thoughts of Carvalho about teaching methods are scrutinised to unveil his conflicting stances: Carvalho was a man able to question the tenets of heurism, but who publicly praised the heurism-like "discovery learning" method years later. The first part of the article contextualises the arrival of heurism in Portugal and how Carvalho attacked its philosophical tenets. In the second part, it dwells on his conflicting positions in relation to pupil-centred approaches. The article concludes with an appreciation of the embedded conflicting nature of the appropriation of concepts of teaching methods, and of Carvalho's contribution to the development of the philosophy of practical work in school science.

The road to understanding is paved with the speaker's intentions: cues to the speaker's attention and intentions affect pronoun comprehension.

PubMed

Nappa, Rebecca; Arnold, Jennifer E

2014-05-01

A series of experiments explore the effects of attention-directing cues on pronoun resolution, contrasting four specific hypotheses about the interpretation of ambiguous pronouns he and she: (1) it is driven by grammatical rules, (2) it is primarily a function of social processing of the speaker's intention to communicate, (3) it is modulated by the listener's own egocentric attention, and (4) it is primarily a function of learned probabilistic cues. Experiment 1 demonstrates that pronoun interpretation is guided by the well-known N1 (first-mention) bias, which is also modulated by both the speaker's gaze and pointing gestures. Experiment 2 demonstrates that a low-level visual capture cue has no effect on pronoun interpretation, in contrast with the social cue of pointing. Experiment 3 uses a novel intentional cue: the same attention-capture flash as in Experiment 2, but with instructions that the cue is intentionally created by the speaker. This cue does modulate the N1 bias, demonstrating the importance of information about the speaker's intentions to pronoun resolution. Taken in sum, these findings demonstrate that pronoun resolution is a process best categorized as driven by an appreciation of the speaker's communicative intent, which may be subserved by a sensitivity to predictive cues in the environment. Copyright © 2014 Elsevier Inc. All rights reserved.

Nuclear export of RNA: Different sizes, shapes and functions.

PubMed

Williams, Tobias; Ngo, Linh H; Wickramasinghe, Vihandha O

2018-03-01

Export of protein-coding and non-coding RNA molecules from the nucleus to the cytoplasm is critical for gene expression. This necessitates the continuous transport of RNA species of different size, shape and function through nuclear pore complexes via export receptors and adaptor proteins. Here, we provide an overview of the major RNA export pathways in humans, highlighting the similarities and differences between each. Its importance is underscored by the growing appreciation that deregulation of RNA export pathways is associated with human diseases like cancer. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

Interdisciplinary Approaches to Astronomy: Cosmic Fiction, Drama and Poetry

NASA Astrophysics Data System (ADS)

Fraknoi, A.

2015-09-01

I have spent four decades teaching introductory astronomy to university students whose primary subject of study is not astronomy, as well as developing activities to help the public appreciate astronomical ideas and developments. One of the more effective tools that I have found for capturing the interest of non-scientists has been approaching astronomy through its influence on the humanities. In this article I examine some examples of astronomical inspiration in the humanities, looking at plays, poetry and fiction. A second paper, devoted to music inspired by astronomy, will appear in a future issue of the CAPjournal.

Toward an integrative approach of cognitive neuroscientific and evolutionary psychological studies of art.

PubMed

De Smedt, Johan; De Cruz, Helen

2010-11-28

This paper examines explanations for human artistic behavior in two reductionist research programs, cognitive neuroscience and evolutionary psychology. Despite their different methodological outlooks, both approaches converge on an explanation of art production and appreciation as byproducts of normal perceptual and motivational cognitive skills that evolved in response to problems originally not related to art, such as the discrimination of salient visual stimuli and speech sounds. The explanatory power of this reductionist framework does not obviate the need for higher-level accounts of art from the humanities, such as aesthetics, art history or anthropology of art.

Theory of the fundamental laser linewidth

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goldberg, P.; Milonni, P.W.; Sundaram, B.

1991-08-01

The theory of the laser linewidth is formulated to account for arbitrarily large output couplings and spatial hole burning. We show explicitly that the linewidth can be interpreted in terms of either spontaneous-emission noise or the amplification of vacuum field modes leaking into the cavity, depending on the ordering of operators in the correlation function determining the laser spectrum. This allows us to derive the Petermann {ital K} factor associated with excess spontaneous-emission noise'' in a physically transparent and mathematically simple way, without the need to introduce adjoint modes of the resonator. It also allows us to straightforwardly include spatial-hole-burningmore » effects, which are found to increase the {ital K} factor and the linewidth in high-gain systems appreciably.« less

Degradation of curcumin: From mechanism to biological implications

PubMed Central

Schneider, Claus; Gordon, Odaine N.; Edwards, Rebecca L.; Luis, Paula B.

2016-01-01

Curcumin is the main bioactive ingredient in turmeric extract and widely consumed as part of the spice mix curry or as dietary supplement. Turmeric has a long history of therapeutic application in traditional Asian medicine. Biomedical studies conducted in the past two decades have identified a large number of cellular targets and effects of curcumin. In vitro curcumin rapidly degrades in an autoxidative transformation to diverse chemical species, formation of which has only recently been appreciated. We discuss how degradation and metabolism of curcumin, through products and their mechanism of formation, provide a basis for the interpretation of preclinical data and clinical studies. We suggest that the previously unrecognized diversity of its degradation products could be an important factor in explaining the polypharmacology of curcumin. PMID:25817068

TRANSVERSE IMPEDANCE OF THE SQUID GIANT AXON DURING CURRENT FLOW

PubMed Central

Cole, Kenneth S.; Baker, Richard F.

1941-01-01

The change in the transverse impedance of the squid giant axon caused by direct current flow has been measured at frequencies from 1 kc. per second to 500 kc. per second. The impedance change is equivalent to an increase of membrane conductance at the cathode to a maximum value approximately the same as that obtained during activity and a decrease at the anode to a minimum not far from zero. There is no evidence of appreciable membrane capacity change in either case. It then follows that the membrane has the electrical characteristics of a rectifier. Interpreting the membrane conductance as a measure of ion permeability, this permeability is increased at the cathode and decreased at the anode. PMID:19873233

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barton, B.A.; Schreck, C.B.; Fowler, L.G.

Juvenile chinook salmon (Oncorhynchus tshawytscha) reared on low-, medium-, or high-lipid diets for 18 weeks were either kept on their respective diets or fasted for 20 d; then they were subjected to a 30-s handling stress or to handling plus continuous confinement. In fish that were handled but not confined, poststress hyperglycemia was greatest in fed fish that received the high-lipid diet and was generally lower in fasted than in fed fish. Plasma cortisol elevations in response to handling or handling plus confinement stress were not appreciably affected by diet type or fasting. The result indicated that prior feeding regimesmore » and the types of diet fed should be considered when one is interpreting the magnitude of hyperglycemic stress responses in juvenile chinook salmon.« less

Towards a sustainable world through human factors and ergonomics: it is all about values.

PubMed

Lange-Morales, Karen; Thatcher, Andrew; García-Acosta, Gabriel

2014-01-01

In this paper, we analyse two approaches that attempt to address how a human factors and ergonomics (HFE) perspective can contribute to the sustainability of the human race. We outline the principles, purposes and fields of application of ergoecology and green ergonomics, and thereafter deal with their context of emergence, and the overlaps in purpose, and principles. Shared values are deduced and related to socio-technical principles for systems' design. Social responsibility and environmental/ecospheric responsibility are the leading threads of ergoecology and green ergonomics, giving rise to the values of: respect for human rights, respect for the Earth, respect for ethical decision-making, appreciation of complexity, respect for transparency and openness, and respect for diversity. We discuss the consequences of considering these values in HFE theory and practice.

Students' Visualization of Diagrams Representing the Human Circulatory System: The Use of Spatial Isomorphism and Representational Conventions

ERIC Educational Resources Information Center

Cheng, Maurice M. W.; Gilbert, John K.

2015-01-01

This study investigated students' interpretation of diagrams representing the human circulatory system. We conducted an interview study with three students aged 14-15 (Year 10) who were studying biology in a Hong Kong school. During the interviews, students were asked to interpret diagrams and relationships between diagrams that represented…

The Theory of Human Capital and the Earnings of Women: A Re-examination of the Evidence. Revised.

ERIC Educational Resources Information Center

Sandell, Steven H.; Shapiro, David

This paper discusses specification and interpretation of human capital models of women's earnings when data on actual work experience are available. It uses the segmented earnings function framework developed by Jacob Mincer and Solomon Polachek and considers the effects of data errors, issues involving data interpretation, consequences of model…

The artful mind meets art history: toward a psycho-historical framework for the science of art appreciation.

PubMed

Bullot, Nicolas J; Reber, Rolf

2013-04-01

Research seeking a scientific foundation for the theory of art appreciation has raised controversies at the intersection of the social and cognitive sciences. Though equally relevant to a scientific inquiry into art appreciation, psychological and historical approaches to art developed independently and lack a common core of theoretical principles. Historicists argue that psychological and brain sciences ignore the fact that artworks are artifacts produced and appreciated in the context of unique historical situations and artistic intentions. After revealing flaws in the psychological approach, we introduce a psycho-historical framework for the science of art appreciation. This framework demonstrates that a science of art appreciation must investigate how appreciators process causal and historical information to classify and explain their psychological responses to art. Expanding on research about the cognition of artifacts, we identify three modes of appreciation: basic exposure to an artwork, the artistic design stance, and artistic understanding. The artistic design stance, a requisite for artistic understanding, is an attitude whereby appreciators develop their sensitivity to art-historical contexts by means of inquiries into the making, authorship, and functions of artworks. We defend and illustrate the psycho-historical framework with an analysis of existing studies on art appreciation in empirical aesthetics. Finally, we argue that the fluency theory of aesthetic pleasure can be amended to meet the requirements of the framework. We conclude that scientists can tackle fundamental questions about the nature and appreciation of art within the psycho-historical framework.

Considerations for the use of human participants in vector biology research: a tool for investigators and regulators.

PubMed

Achee, Nicole L; Youngblood, Laura; Bangs, Michael J; Lavery, James V; James, Stephanie

2015-02-01

A thorough search of the existing literature has revealed that there are currently no published recommendations or guidelines for the interpretation of US regulations on the use of human participants in vector biology research (VBR). An informal survey of vector biologists has indicated that issues related to human participation in vector research have been largely debated by academic, national, and local Institutional Review Boards (IRBs) in the countries where the research is being conducted, and that interpretations and subsequent requirements made by these IRBs have varied widely. This document is intended to provide investigators and corresponding scientific and ethical review committee members an introduction to VBR methods involving human participation and the legal and ethical framework in which such studies are conducted with a focus on US Federal Regulations. It is also intended to provide a common perspective for guiding researchers, IRB members, and other interested parties (i.e., public health officials conducting routine entomological surveillance) in the interpretation of human subjects regulations pertaining to VBR.

The Design of Hand Gestures for Human-Computer Interaction: Lessons from Sign Language Interpreters.

PubMed

Rempel, David; Camilleri, Matt J; Lee, David L

2015-10-01

The design and selection of 3D modeled hand gestures for human-computer interaction should follow principles of natural language combined with the need to optimize gesture contrast and recognition. The selection should also consider the discomfort and fatigue associated with distinct hand postures and motions, especially for common commands. Sign language interpreters have extensive and unique experience forming hand gestures and many suffer from hand pain while gesturing. Professional sign language interpreters (N=24) rated discomfort for hand gestures associated with 47 characters and words and 33 hand postures. Clear associations of discomfort with hand postures were identified. In a nominal logistic regression model, high discomfort was associated with gestures requiring a flexed wrist, discordant adjacent fingers, or extended fingers. These and other findings should be considered in the design of hand gestures to optimize the relationship between human cognitive and physical processes and computer gesture recognition systems for human-computer input.

Connections Between Science and Spirituality

NASA Astrophysics Data System (ADS)

Garen, David C.

2006-07-01

I would like to continue the discussion ofpoints raised in William Carter's response toRobert Frodeman's Eos Forum article Carter,2006; Frodeman, 2005. I have appreciatedFrodeman's work and feel that perspectiveson science deriving from humanities, philosophy,and religion can add depth, insight,and meaning to our endeavors. I would liketo broaden the discussion beyond just spacepolicy to include the relationship betweenscience in general and these, what I wouldcall, spiritual issues.

Holography: A Transformative Technology for Learning and Human Performance Improvement

ERIC Educational Resources Information Center

Frazer, Gary W.; Stevens, George H.

2015-01-01

Most past and current learning technologies have been one- or two-dimensional in presentation. This may be fine if one is looking at a map or even a fine painting. However, to fully appreciate the detail of a statue or a machine part, it is better to be able to look at it from all sides. Use of holographic images allows an item to be shared with a…

An antibody precipitating urease and its possible relation to gastric ulcer 1

PubMed Central

Freisinger, F. S.

1963-01-01

An antibody precipitating urease was found in 171 out of 180 human sera. Data obtained on limited material (50 cases) suggest that the anti-urease titre is appreciably higher in the serum of patients suffering from gastric ulcer. This is a pointer towards a possible antigen-antibody mechanism in the genesis of chronic gastric ulceration. ImagesFIG. 1FIG. 2FIG. 3 PMID:14086040

Adventures in near-Earth object exploration.

PubMed

Asphaug, Erik

2006-06-02

Asteroids, because of the hazard they pose to Earth, are compelling targets for robotic and human space exploration. Yet because of their exotic low-gravity environment, simply landing on an asteroid appears to be much more challenging than we had appreciated 5 or 10 years ago. Thanks to a bold new mission from Japan that has made the first asteroid sample return attempt, this goal is now within our reach.

The world's largest floods, past and present: Their causes and magnitudes

USGS Publications Warehouse

O'Connor, Jim E.; Costa, John E.

2004-01-01

Floods are among the most powerful forces on earth. Human societies worldwide have lived and died with floods from the very beginning, spawning a prominent role for floods within legends, religions, and history. Inspired by such accounts, geologists, hydrologists, and historians have studied the role of floods on humanity and its supporting ecosystems, resulting in new appreciation for the many-faceted role of floods in shaping our world. Part of this appreciation stems from ongoing analysis of long-term streamflow measurements, such as those recorded by the U.S. Geological Survey's (USGS) streamflow gaging network. But the recognition of the important role of flooding in shaping our cultural and physical landscape also owes to increased understanding of the variety of mechanisms that cause floods and how the types and magnitudes of floods can vary with time and space. The USGS has contributed to this understanding through more than a century of diverse research activities on many aspects of floods, including their causes, effects, and hazards. This Circular summarizes a facet of this research by describing the causes and magnitudes of the world's largest floods, including those measured and described by modern methods in historic times, as well as floods of prehistoric times, for which the only records are those left by the floods themselves.

Reflective journals: unmasking student perceptions of anatomical education.

PubMed

Lazarus, L; Sookrajh, R; Satyapal, K S

2017-01-01

In medical education, reflection has been considered to be a core skill in professional competence. The anatomy laboratory is an ideal setting for faculty/ student interaction and provides invaluable opportunities for active learning and reflection on anatomical knowledge. This study was designed to record student attitudes regarding human cadaveric dissection, explore their experiences of anatomy through an analysis of their journal-reflective writings and determine whether this type of creative writing had a beneficial effect on those students who chose to complete them. A total of 75 journals from Medical and Allied Health Science students were collected and analysed. Results were categorised according to the following themes: (i) Dissecting room stressors (27.6%); (ii) Educational value of dissection (26.3%); (iii) Appreciation, Gratitude, Respect and Curiosity for the cadaver (18.9%); (iv) Positive and negative sentiments expressed in the dissecting room (25.8%); (v) Benefit of alternate teaching modalities (4.6%); (vi) Spirituality/Religious Beliefs (3.7%); (vii) Shared humanity and emotional bonds (3.69%); (viii) Acknowledgement of human anatomical variations (3.2%); (ix) Beauty and complexity of the human body (1.8%) and (x) Psychological detachment (0.9%). Students appreciated the opportunity to share their emotions and reflect on the humanistic dimension of anatomy as a subject. Student reflections illustrated clearly their thoughts and some of the difficult issues with which they wrestled. The anatomy laboratory is seen as the budding clinician's first encounter with a patient, albeit a cadaver. This was the first time that reflective journals were given to students in the discipline. Reflective journals allow students to express themselves in an open-ended and creative fashion. It also assists students to integrate anatomy and clinical medicine and assists in applying their basic anatomical knowledge in an authentic, yet safe environment.

The protective role of body appreciation against media-induced body dissatisfaction.

PubMed

Andrew, Rachel; Tiggemann, Marika; Clark, Levina

2015-09-01

This study aimed to examine the protective role of positive body image against negative effects produced by viewing thin-idealised media. University women (N=68) completed trait measures of body appreciation and media protective strategies. At a subsequent session, participants viewed 11 thin-ideal advertisements. Body dissatisfaction was assessed before and after advertisement exposure, and state measures of self-objectification, appearance comparison, and media protective strategies were completed. Results indicated that body appreciation predicted less change in body dissatisfaction following exposure, such that participants with low body appreciation experienced increased body dissatisfaction, while those with high body appreciation did not. Although state appearance comparison predicted increased body dissatisfaction, neither state self-objectification nor appearance comparison accounted for body appreciation's protective effect. Trait and state media protective strategies positively correlated with body appreciation, but also did not account for body appreciation's protective effect. The results point to intervention targets and highlight future research directions. Copyright © 2015 Elsevier Ltd. All rights reserved.

Spectral Fluorescence Properties of an Anionic Oxacarbocyanine Dye in Complexes with Human Serum Albumin

NASA Astrophysics Data System (ADS)

Pronkin, P. G.; Tatikolov, A. S.

2015-07-01

The spectral fluorescence properties of the anionic oxacarbocyanine dye 3,3'-di-(γ-sulfopropyl)-5,5'-diphenyl-9-ethyloxacarbocyanine betaine (OCC) were studied in solutions and in complexes with human serum albumin (HSA). Interaction with HSA leads to a significant increase in the fluorescence of the dye. We studied quenching of the fluorescence of OCC in a complex with HSA by ibuprofen and warfarin. Data on quenching of fluorescence by ibuprofen indicate binding of the dye to binding site II of subdomain IIIA in the HSA molecule. Synchronous fluorescence spectra of human serum albumin in the presence of OCC showed that complexation with OCC does not lead to appreciable rearrangement of the protein molecule at the binding site.

The human mouth: oral functions in a social complexity perspective.

PubMed

Eriksen, Harald M; Dimitrov, Vladimir

2003-06-01

In the dental and medical literature, the mouth and oral functions are usually presented in a biomedical context. However, there may be a need for a broader perspective if we are to appreciate the importance of the human mouth as an organ with diverse functions. The paradigm of complexity appears to be of relevance in our understanding the social and psychological characteristics of the human mouth in addition to its biological functions. Examples such as the pleasures of taste, social aspects of eating, the importance of linguistics and communication are illustrations of some of the social and psychological aspects of oral functions. Professional knowledge related to such issues is important in our understanding the patient's priorities and in performing the relevant diagnosis and treatment planning.

Plant Hormones: Key Players in Gut Microbiota and Human Diseases?

PubMed

Chanclud, Emilie; Lacombe, Benoît

2017-09-01

It is well established that plant hormones such as auxins, cytokinins (CKs), and abscisic acid (ABA) not only govern important plant physiological traits but are key players in plant-microbe interactions. A poorly appreciated fact, however, is that both microbes and animals produce and perceive plant hormones and their mimics. Moreover, dietary plant hormones impact on human physiological process such as glucose assimilation, inflammation, and cell division. This leads us to wonder whether plant hormones could ensure functions in microbes per se as well as in animal-microbe interactions. We propose here and explore the hypothesis that plant hormones play roles in animal-microbiota relationships, with consequences for human health. Copyright © 2017 Elsevier Ltd. All rights reserved.

Humans Rapidly Learn Grammatical Structure in a New Musical Scale

PubMed Central

Loui, Psyche; Wessel, David L.; Hudson Kam, Carla L.

2010-01-01

Knowledge of musical rules and structures has been reliably demonstrated in humans of different ages, cultures, and levels of music training, and has been linked to our musical preferences. However, how humans acquire knowledge of and develop preferences for music remains unknown. The present study shows that humans rapidly develop knowledge and preferences when given limited exposure to a new musical system. Using a non-traditional, unfamiliar musical scale (Bohlen-Pierce scale), we created finite-state musical grammars from which we composed sets of melodies. After 25–30 min of passive exposure to the melodies, participants showed extensive learning as characterized by recognition, generalization, and sensitivity to the event frequencies in their given grammar, as well as increased preference for repeated melodies in the new musical system. Results provide evidence that a domain-general statistical learning mechanism may account for much of the human appreciation for music. PMID:20740059

Humans Rapidly Learn Grammatical Structure in a New Musical Scale.

PubMed

Loui, Psyche; Wessel, David L; Hudson Kam, Carla L

2010-06-01

Knowledge of musical rules and structures has been reliably demonstrated in humans of different ages, cultures, and levels of music training, and has been linked to our musical preferences. However, how humans acquire knowledge of and develop preferences for music remains unknown. The present study shows that humans rapidly develop knowledge and preferences when given limited exposure to a new musical system. Using a non-traditional, unfamiliar musical scale (Bohlen-Pierce scale), we created finite-state musical grammars from which we composed sets of melodies. After 25-30 min of passive exposure to the melodies, participants showed extensive learning as characterized by recognition, generalization, and sensitivity to the event frequencies in their given grammar, as well as increased preference for repeated melodies in the new musical system. Results provide evidence that a domain-general statistical learning mechanism may account for much of the human appreciation for music.

Trust, choice and power in mental health care: experiences of patients with psychosis.

PubMed

Laugharne, Richard; Priebe, Stefan; McCabe, Rose; Garland, Natasha; Clifford, Damian

2012-09-01

Trust, choice and power are critical issues in clinical practice, public policies and a post-modern understanding of mental health care. We aimed to investigate the experiences and attitudes of patients with psychosis in relation to trust, choice and power. We conducted 20 in-depth interviews with patients with psychotic disorders in care of NHS services. The interviews were subjected to thematic analysis. Patients discussed aspects of their care in terms of dimensions that enhance or undermine trust, choice and power. Two interpretive themes emerged from this data. First, patients perceive the need for a shifting balance of power, according to the severity of their illness and their own experience of care, but feel that threats of coercion and neglect disable them. Second, they appreciate the expertise of clinicians, but particularly value 'the personal touch' that goes beyond this expertise, including personal disclosure about their own lives, common acts of kindness and conversation outside clinical matters. Patients view trust as a two-way process with responsibility shared between patient and clinician. The active involvement of patients with psychosis in their individual care may be strengthened, particularly when they are not acutely ill and have more experience of their illness. While patients value expertise and respect in interactions with clinicians, they also appreciate a 'personal touch', which may go beyond current notions of professionalism.

Modeling GW170817 based on numerical relativity and its implications

NASA Astrophysics Data System (ADS)

Shibata, Masaru; Fujibayashi, Sho; Hotokezaka, Kenta; Kiuchi, Kenta; Kyutoku, Koutarou; Sekiguchi, Yuichiro; Tanaka, Masaomi

2017-12-01

Gravitational-wave observation together with a large number of electromagnetic observations shows that the source of the latest gravitational-wave event, GW170817, detected primarily by advanced LIGO, is the merger of a binary neutron star. We attempt to interpret this observational event based on our results of numerical-relativity simulations performed so far, paying particular attention to the optical and infrared observations. We finally reach a conclusion that this event is described consistently by the presence of a long-lived hypermassive or supramassive neutron star as the merger remnant because (i) significant contamination by lanthanide elements along our line of sight to this source can be avoided by the strong neutrino irradiation from it and (ii) it could play a crucial role in producing an ejecta component of appreciable mass with fast motion in the postmerger phase. We also point out that (I) the neutron-star equation of state has to be sufficiently stiff (i.e., the maximum mass of cold spherical neutron stars, Mmax, has to be appreciably higher than 2 M⊙) in order for a long-lived massive neutron star to be formed as the merger remnant for the binary systems of GW170817, for which the initial total mass is ≳2.73 M⊙ , and (II) the absence of optical counterparts associated with relativistic ejecta suggests a not-extremely-high value of Mmax approximately as 2.15 - 2.25 M⊙ .

Eye Movements during Art Appreciation by Students Taking a Photo Creation Course.

PubMed

Ishiguro, Chiaki; Yokosawa, Kazuhiko; Okada, Takeshi

2016-01-01

Previous studies have focused on the differences in the art appreciation process between individuals, and indicated that novice viewers of artworks, in comparison to experts, rarely consider the creation process of the artwork or how this may relate to style. However, behavioral changes in individuals after educational interventions have not been examined. Art education researchers claim that technical knowledge and creation experiences help novice viewers to pay attention to technical features of artwork. Therefore, an artistic photo creation course was designed and conducted to help students acquire techniques and procedural knowledge of photo creation. The present study verified whether students' viewing strategies during appreciation of photographs changed after the course. Twenty-one students participated in two sessions, viewing the same 12 photographs before and after the course. Based on the analysis of recorded eye movements, the results indicated that the students' perceptual exploration became more active with photographs containing recognizable subjects (i.e., humans and objects), and their global saccades increased when they viewed classic photography, one of the categories of photography covered in the course. Interview data after the course indicated that students became aware of the technical effects in photographs. These results suggest that students' viewing strategies may change following a course, as assessed by behavioral measures of eye movements. Further examination is needed to validate this approach to educational effect measurement.

Eye Movements during Art Appreciation by Students Taking a Photo Creation Course

PubMed Central

Ishiguro, Chiaki; Yokosawa, Kazuhiko; Okada, Takeshi

2016-01-01

Previous studies have focused on the differences in the art appreciation process between individuals, and indicated that novice viewers of artworks, in comparison to experts, rarely consider the creation process of the artwork or how this may relate to style. However, behavioral changes in individuals after educational interventions have not been examined. Art education researchers claim that technical knowledge and creation experiences help novice viewers to pay attention to technical features of artwork. Therefore, an artistic photo creation course was designed and conducted to help students acquire techniques and procedural knowledge of photo creation. The present study verified whether students' viewing strategies during appreciation of photographs changed after the course. Twenty-one students participated in two sessions, viewing the same 12 photographs before and after the course. Based on the analysis of recorded eye movements, the results indicated that the students' perceptual exploration became more active with photographs containing recognizable subjects (i.e., humans and objects), and their global saccades increased when they viewed classic photography, one of the categories of photography covered in the course. Interview data after the course indicated that students became aware of the technical effects in photographs. These results suggest that students' viewing strategies may change following a course, as assessed by behavioral measures of eye movements. Further examination is needed to validate this approach to educational effect measurement. PMID:27471485

Bridging two worlds that care about art: psychological and historical approaches to art appreciation.

PubMed

Thompson, William Forde; Antliff, Mark

2013-04-01

Art appreciation often involves contemplation beyond immediate perceptual experience. However, there are challenges to incorporating such processes into a comprehensive theory of art appreciation. Can appreciation be captured in the responses to individual artworks? Can all forms of contemplation be defined? What properties of artworks trigger contemplation? We argue that such questions are fundamental to a psycho-historical framework for the science of art appreciation, and we suggest research that may assist in refining this framework.

Peptide promotes overcoming of the division limit in human somatic cell.

PubMed

Khavinson, V Kh; Bondarev, I E; Butyugov, A A; Smirnova, T D

2004-05-01

We previously showed that treatment of normal human diploid cells with Epithalon (Ala-Glu-Asp-Gly) induced expression of telomerase catalytic subunit, its enzymatic activity, and elongation of telomeres. Here we studied the effect of this peptide on proliferative potential of human fetal fibroblasts. Primary pulmonary fibroblasts derived from a 24-week fetus lost the proliferative potential at the 34th passage. The mean size of telomeres in these cells was appreciably lower than during early passages (passage 10). Addition of Epithalon to aging cells in culture induced elongation of telomeres to the size comparable to their length during early passages. Peptide-treated cells with elongated telomeres made 10 extra divisions (44 passages) in comparison with the control and continued dividing. Hence, Epithalon prolonged the vital cycle of normal human cells due to overcoming the Heyflick limit.

The significant human-animal bond: Pets with cancer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weller, R.E.

Veterinarians have responsibilities to both the animal and its owner. In the past several years there has been an increased awareness and concern about human-animal bonds. As a result, we have begun to appreciate the nature, strength, and significance of bonds that develop between humans and companion animals. It is typical for a pet to be perceived as and treated as a member of the family and as a result, animals provide special and beneficial relationships for many years. It is partly because of this role of the pet in promoting human health and happiness that we as veterinarians havemore » an obligation to assist both owner and animal. The mark of the good practitioner concerns not only the ability to diagnose and treat accurately, but also the ability to show understanding and compassionate judgement.« less

A proteome-scale map of the human interactome network

PubMed Central

Rolland, Thomas; Taşan, Murat; Charloteaux, Benoit; Pevzner, Samuel J.; Zhong, Quan; Sahni, Nidhi; Yi, Song; Lemmens, Irma; Fontanillo, Celia; Mosca, Roberto; Kamburov, Atanas; Ghiassian, Susan D.; Yang, Xinping; Ghamsari, Lila; Balcha, Dawit; Begg, Bridget E.; Braun, Pascal; Brehme, Marc; Broly, Martin P.; Carvunis, Anne-Ruxandra; Convery-Zupan, Dan; Corominas, Roser; Coulombe-Huntington, Jasmin; Dann, Elizabeth; Dreze, Matija; Dricot, Amélie; Fan, Changyu; Franzosa, Eric; Gebreab, Fana; Gutierrez, Bryan J.; Hardy, Madeleine F.; Jin, Mike; Kang, Shuli; Kiros, Ruth; Lin, Guan Ning; Luck, Katja; MacWilliams, Andrew; Menche, Jörg; Murray, Ryan R.; Palagi, Alexandre; Poulin, Matthew M.; Rambout, Xavier; Rasla, John; Reichert, Patrick; Romero, Viviana; Ruyssinck, Elien; Sahalie, Julie M.; Scholz, Annemarie; Shah, Akash A.; Sharma, Amitabh; Shen, Yun; Spirohn, Kerstin; Tam, Stanley; Tejeda, Alexander O.; Trigg, Shelly A.; Twizere, Jean-Claude; Vega, Kerwin; Walsh, Jennifer; Cusick, Michael E.; Xia, Yu; Barabási, Albert-László; Iakoucheva, Lilia M.; Aloy, Patrick; De Las Rivas, Javier; Tavernier, Jan; Calderwood, Michael A.; Hill, David E.; Hao, Tong; Roth, Frederick P.; Vidal, Marc

2014-01-01

SUMMARY Just as reference genome sequences revolutionized human genetics, reference maps of interactome networks will be critical to fully understand genotype-phenotype relationships. Here, we describe a systematic map of ~14,000 high-quality human binary protein-protein interactions. At equal quality, this map is ~30% larger than what is available from small-scale studies published in the literature in the last few decades. While currently available information is highly biased and only covers a relatively small portion of the proteome, our systematic map appears strikingly more homogeneous, revealing a “broader” human interactome network than currently appreciated. The map also uncovers significant inter-connectivity between known and candidate cancer gene products, providing unbiased evidence for an expanded functional cancer landscape, while demonstrating how high quality interactome models will help “connect the dots” of the genomic revolution. PMID:25416956

Remote sensing as a source of land cover information utilized in the universal soil loss equation

NASA Technical Reports Server (NTRS)

Morris-Jones, D. R.; Morgan, K. M.; Kiefer, R. W.; Scarpace, F. L.

1979-01-01

In this study, methods for gathering the land use/land cover information required by the USLE were investigated with medium altitude, multi-date color and color infrared 70-mm positive transparencies using human and computer-based interpretation techniques. Successful results, which compare favorably with traditional field study methods, were obtained within the test site watershed with airphoto data sources and human airphoto interpretation techniques. Computer-based interpretation techniques were not capable of identifying soil conservation practices but were successful to varying degrees in gathering other types of desired land use/land cover information.

42 CFR 37.50 - Interpreting and classifying chest radiographs-film.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Interpreting and classifying chest radiographs-film. 37.50 Section 37.50 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Radiographs § 37.50 Interpreting and classifying chest radiographs—film. (a) Chest radiographs must be...

PEER REVIEW AS A QA TOOL FOR PHOTO INTERPRETATION (PRESENTED TAMPA, FL)

EPA Science Inventory

Remotely Sensed (RS) images are used in may ways in the EPA. Eventually, the photo may be "interpreted," When images are interpreted, attempts are made by humans to determine what is on the ground (or in the air) by examining the photo or image, and the implementation ...

PEER REVIEW AS A QA TOOL FOR PHOTO INTERPRETATION

EPA Science Inventory

Remotely Sensed (RS) images are used in many ways in the EPA. Eventually, the photo may be interpreted. When images are interpreted, attempts are made by humans to determine what is on the ground (or in the air) by examining the photo or image, and the implementation of Quality ...

Two Interpretive Systems for Natural Language?

ERIC Educational Resources Information Center

Frazier, Lyn

2015-01-01

It is proposed that humans have available to them two systems for interpreting natural language. One system is familiar from formal semantics. It is a type based system that pairs a syntactic form with its interpretation using grammatical rules of composition. This system delivers both plausible and implausible meanings. The other proposed system…

Appreciation of historical events and characters: their relationship with national identity and collective self-esteem in a sample of public school teachers from the city of Lima.

PubMed

Rottenbacher de Rojas, Jan Marc

2010-11-01

This study analyzes the relation between national identity and the appreciation of the characters and events of Peruvian history in a sample of public school teachers from the city of Lima (N = 99). Adapted versions of the NATID Scale (Keillor et al., 1996) and the CSES Scale (Luhtanen & Crocker, 1992) are used as measures of national identity. National pride and interest in knowing about Peruvian history are variables also included in this study. The study shows that appreciation of historical characters is more positive than appreciation of historical events. There is a positive association between national identity and appreciation of Peruvian historical characters. A multiple linear regression model is proposed; this model shows that appreciation of cultural heritage and national pride has a positive impact on the appreciation of characters of Peruvian history.

Use of narratives to enhance learning of research ethics in residents and researchers.

PubMed

Sim, Kang; Sum, Min Yi; Navedo, Deborah

2015-03-10

Past didactic pedagogy on biomedical research ethics and informed consent in our program had resulted in passive memorization of information and disengaged learning within psychiatry residents and clinical researchers. The question is how do we better motivate and engage learners within the session. Thus, we incorporated narratives into the learning environment and hypothesised that the use of narratives in the teaching of biomedical research ethics and informed consent would be associated with greater engagement, motivation, understanding, reflective learning and effectiveness of the teaching session. The narratives were chosen from the history of research ethics and the humanities literature related to human subject research. Learners were asked to provide post-session feedback through an anonymised questionnaire on their learning session. An outcomes logic model was used for assessment with focus on immediate outcomes such as engagement, motivation, understanding and reflective learning. Overall, 70.5% (N = 273) of the learners responded to the questionnaire. Amongst the respondents, 92.6% (N = 253) of the participants ranked use of narratives as most helpful in appreciating the historical context of research ethics and informed consent in research. The majority felt engaged (89.8%, N = 245), more motivated to learn (77.5%, N = 212) and better equipped (86.4%, N = 236) about the subject matter. Better appreciation of the learning topic, engagement, motivation to learn, equipping were strongly correlated with the promotion of reflective learning, effectiveness of teaching, promotion of critical thinking and overall positive rating of the teaching session on research ethics (all p < 0.001). Multivariate analyses found that the use of narratives was associated with higher overall rating of the teaching session (p = 0.003) and promotion of critical thinking (p = 0.02). Results revealed that the use of narratives could enhance engagement, appreciation of biomedical research ethics and informed consent, and address underlying motivational factors behind learning and understanding of research ethics.

Learning the Languages of Appreciation

ERIC Educational Resources Information Center

White, Paul

2014-01-01

In his work with schools and other workplaces, psychologist Paul White has learned that many programs designed to appreciate employees fall flat because the appreciation is too generic or involves something the employees don't want (such as getting up in front of a group). Effective appreciation is (1) offered regularly, (2) valued by the…

Radiologic-pathologic Correlation-An Advanced Fourth-year Elective: How We Do It.

PubMed

Hartman, Matthew; Silverman, Jan; Spruill, Laura; Hill, Jeanne

2016-07-01

Traditionally, the radiology elective has been designed to teach medical students the fundamentals of radiologic interpretation. When questioned, many students state that they want to take a radiology elective so they can "interpret images." For the students on radiology, rotation/elective education was often passive, consisting of didactic conferences and observational shadowing of radiologists as they interpreted images. Students had only a superficial appreciation of how radiologists interacted with clinical services, multidisciplinary teams, and pathology. There was very little emphasis on imaging appropriateness or the most efficient and effective imaging for various clinical problems. With the expansion of numerous imaging modalities and the emphasis on patient-centered care, including imaging safety and dose reduction, it is important to change the focus of radiology education from interpretation to the optimal integration of imaging into clinical medicine. Radiology-pathology (rad path) electives were created at Allegheny General Hospital and the Medical University of South Carolina as a new option to provide a high-quality advanced elective for fourth-year medical students. These electives enable students to correlate radiologic images with gross and microscopic pathology specimens, thus increasing their knowledge and understanding of both. The rad path elective combines aspects of surgery, radiology, and pathology and requires students to be active learners. The implementation of this elective is an exciting work in progress that has been evolving over the past 2 and 4 years at Medical University of South Carolina and Allegheny General Hospital, respectively. We will discuss the historical basis for the elective, the advantages and challenges of having such an integrated course, and some different strategies for creating a rad path elective. Copyright © 2016 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

Upper flow regime sheets, lenses and scour fills: Extending the range of architectural elements for fluvial sediment bodies

NASA Astrophysics Data System (ADS)

Fielding, Christopher R.

2006-08-01

Fluvial strata dominated internally by sedimentary structures of interpreted upper flow regime origin are moderately common in the rock record, yet their abundance is not appreciated and many examples may go unnoticed. A spectrum of sedimentary structures is recognised, all of which occur over a wide range of scale: 1. cross-bedding with humpback, sigmoidal and ultimately low-angle cross-sectional foreset geometries (interpreted as recording the transition from dune to upper plane bed bedform stability field), 2. planar/flat lamination with parting lineation, characteristic of the upper plane bed phase, 3. flat and low-angle lamination with minor convex-upward elements, characteristic of the transition from upper plane bed to antidune stability fields, 4. convex-upward bedforms, down- and up-palaeocurrent-dipping, low-angle cross-bedding and symmetrical drapes, interpreted as the product of antidunes, and 5. backsets terminating updip against an upstream-dipping erosion surface, interpreted as recording chute and pool conditions. In some fluvial successions, the entirety or substantial portions of channel sandstone bodies may be made up of such structures. These Upper Flow Regime Sheets, Lenses and Scour Fills (UFR) are defined herein as an extension of Miall's [Miall, A.D., 1985. Architectural-element analysis: a new method of facies analysis applied to fluvial deposits. Earth Sci. Rev. 22: 261-308.] Laminated Sand Sheets architectural element. Given the conditions that favour preservation of upper flow regime structures (rapid changes in flow strength), it is suggested that the presence of UFR elements in ancient fluvial successions may indicate sediment accumulation under the influence of a strongly seasonal palaeoclimate that involves a pronounced seasonal peak in precipitation and runoff.

Medicine as combining natural and human science.

PubMed

Dreyfus, Hubert L

2011-08-01

Medicine is unique in being a combination of natural science and human science in which both are essential. Therefore, in order to make sense of medical practice, we need to begin by drawing a clear distinction between the natural and the human sciences. In this paper, I try to bring the old distinction between the Geistes and Naturwissenschaften up to date by defending the essential difference between a realist explanatory theoretical study of nature including the body in which the scientist discovers the causal properties of natural kinds and the interpretive understanding of human beings as embodied agents which, as Charles Taylor has convincingly argued, requires a hermeneutic account of self-interpreting human practices.

Evaluation of pharmacy students' knowledge and perceptions of pharmacogenetics before and after a simulation activity.

PubMed

Patel, Radha V; Chudow, Melissa; Vo, Teresa T; Serag-Bolos, Erini S

The purpose of this study was to evaluate students' knowledge and perceptions of the clinical application of pharmacogenetics through a simulation activity and to assess communication of pharmacogenetic-guided treatment recommendations utilizing standardized patients. Third-year students in the four-year doctor of pharmacy (PharmD) program at University of South Florida College of Pharmacy completed a pharmacogenetics simulation involving a patient case review, interpretation of pharmacogenetic test results, completion of a situation, background, assessment, recommendation (SBAR) note with drug therapy recommendations, and patient counseling. Voluntary assessments were completed before and after the simulation, which included demographics, knowledge, and perceptions of students' ability to interpret and communicate pharmacogenetic results. Response rates for the pre- and post-simulation assessments were 109 (98%) and 104 (94%), respectively. Correct responses in application-type questions improved after the simulation (74%) compared to before the simulation (44%, p < 0.01). Responses to perception questions shifted towards "strongly agree" or "agree" after the simulation (p < 0.01). The simulation gave students an opportunity to apply pharmacogenetics knowledge and allowed them to gain an appreciation of pharmacists' roles within the pharmacogenetics field. Copyright © 2017 Elsevier Inc. All rights reserved.

The meaning of body experience evaluation in oncology.

PubMed

Slatman, Jenny

2011-12-01

Evaluation of quality of life, psychic and bodily well-being is becoming increasingly important in oncology aftercare. This type of assessment is mainly carried out by medical psychologists. In this paper I will seek to show that body experience valuation has, besides its psychological usefulness, a normative and practical dimension. Body experience evaluation aims at establishing the way a person experiences and appreciates his or her physical appearance, intactness and competence. This valuation constitutes one's 'body image'. While, first, interpreting the meaning of body image and, second, indicating the limitations of current psychological body image assessment, I argue that the normative aspect of body image is related to the experience of bodily wholeness or bodily integrity. Since this experience is contextualized by a person's life story, evaluation should also focus on narrative aspects. I finally suggest that the interpretation of body experience is not only valuable to assess a person's quality of life after treatment, but that it can also be useful in counseling prior to interventions, since it can support patients in making decisions about interventions that will change their bodies. To apply this type of evaluation to oncology practice, a rich and tailored vocabulary of body experiences has to be developed.

[Primary healthcare and the construction of meanings of oral health: a social constructionist interpretation of discourses of the elderly].

PubMed

Bulgarelli, Alexandre Favero; Pinto, Ione Carvalho; Lorenzi, Carla Guanaes; Villa, Teresa Cristina Scatena; Mestriner, Soraya Fernandes; Silva, Rosalina Carvalho da

2012-05-01

Dentistry currently reveals itself to be open to new ideas about the construction of meanings for oral health. This openness leads to the social production of health revealing the contextualization of the social and historical aspects of the sundry knowledge in the development of oral health for different communities. With this research, we seek to build meanings for oral health with a group of elderly people. With this objective in mind, we propose an approximation between discourses on oral health mentioned by the elderly and the Social Constructionist discourse. We interviewed 14 elderly people enrolled in a Family Health Unit in Ribeirão Preto, State of São Paulo, in the first semester of 2010, and identified two interpretative repertoires through Discourse Analysis, which showed the relationship between 1 - Lack of information and dental assistance in childhood, and 2 - Primary Health Care building the meaning of oral health. We concluded that Social Constructionism works epistemologically for the construction of meanings for oral health and that primary health is essential for appreciation and health care that enables the construction of meanings in oral health by the elderly that create conditions for self-care and healthy attitudes.

Lymphocyte-based model systems for allergy research: a historic overview.

PubMed

Neunkirchner, Alina; Schmetterer, Klaus G; Pickl, Winfried F

2014-01-01

During the last decades, a multitude of studies applying distinct in vitro and in vivo model systems have contributed greatly to our better understanding of the initiation and regulation of inflammatory processes leading to allergic diseases. Over the years, it has become evident that among lymphocytes, not only IgE-producing B cells and allergy-orchestrating CD4(+) helper cells but also cytotoxic CD8(+) T cells, γδ-T cells and innate lymphoid cells, as well as regulatory lymphocytes, might critically shape the immune response towards usually innocuous allergens. In this review, we provide a historic overview of pioneering work leading to the establishment of important lymphocyte-based model systems for allergy research. Moreover, we contrast the original findings with our currently more refined knowledge to appreciate the actual validity of the respective models and to reassess the conclusions obtained from them. Conflicting studies and interpretations are identified and discussed. The tables are intended to provide an easy overview of the field not only for scientists newly entering the field but also for the broader readership interested in updating their knowledge. Along those lines, herein we discuss in vitro and in vivo approaches to the investigation of lymphocyte effector cell activation, polarization and regulation, and describe depletion and adoptive transfer models along with gene knockout and transgenic (tg) methodologies. In addition, novel attempts to establish humanized T cell antigen receptor tg mouse models for allergy research are described and discussed. © 2014 S. Karger AG, Basel.

Confirmatory factor analytic structure and measurement invariance of quantitative autistic traits measured by the social responsiveness scale-2.

PubMed

Frazier, Thomas W; Ratliff, Kristin R; Gruber, Chris; Zhang, Yi; Law, Paul A; Constantino, John N

2014-01-01

Understanding the factor structure of autistic symptomatology is critical to the discovery and interpretation of causal mechanisms in autism spectrum disorder. We applied confirmatory factor analysis and assessment of measurement invariance to a large (N = 9635) accumulated collection of reports on quantitative autistic traits using the Social Responsiveness Scale, representing a broad diversity of age, severity, and reporter type. A two-factor structure (corresponding to social communication impairment and restricted, repetitive behavior) as elaborated in the updated Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5) criteria for autism spectrum disorder exhibited acceptable model fit in confirmatory factor analysis. Measurement invariance was appreciable across age, sex, and reporter (self vs other), but somewhat less apparent between clinical and nonclinical populations in this sample comprised of both familial and sporadic autism spectrum disorders. The statistical power afforded by this large sample allowed relative differentiation of three factors among items encompassing social communication impairment (emotion recognition, social avoidance, and interpersonal relatedness) and two factors among items encompassing restricted, repetitive behavior (insistence on sameness and repetitive mannerisms). Cross-trait correlations remained extremely high, that is, on the order of 0.66-0.92. These data clarify domains of statistically significant factoral separation that may relate to partially-but not completely-overlapping biological mechanisms, contributing to variation in human social competency. Given such robust intercorrelations among symptom domains, understanding their co-emergence remains a high priority in conceptualizing common neural mechanisms underlying autistic syndromes.

The Double Helix: Applying an Ethic of Care to the Duty to Warn Genetic Relatives of Genetic Information.

PubMed

Weaver, Meaghann

2016-03-01

Genetic testing reveals information about a patient's health status and predictions about the patient's future wellness, while also potentially disclosing health information relevant to other family members. With the increasing availability and affordability of genetic testing and the integration of genetics into mainstream medicine, the importance of clarifying the scope of confidentiality and the rules regarding disclosure of genetic findings to genetic relatives is prime. The United Nations International Declaration on Human Genetic Data urges an appreciation for principles of equality, justice, solidarity and responsibility in the context of genetic testing, including a commitment to honoring the privacy and security of the person tested. Considering this global mandate and recent professional statements in the context of a legal amendment to patient privacy policies in Australia, a fresh scrutiny of the legal history of a physician's duty to warn is warranted. This article inquiries whether there may be anything ethically or socially amiss with a potential future recommendation for health professionals or patients to universally disclose particular cancer predisposition genetic diagnosis to genetic family members. While much of the discussion remains applicable to all genetic diagnosis, the article focuses on the practice of disclosure within the context of BRCA1/2 diagnosis. An 'ethic of care' interpretation of legal tradition and current practice will serve to reconcile law and medical policy on the issue of physician disclosure of genetic results to family members without patient consent. © 2015 John Wiley & Sons Ltd.

Space shuttle’s liftoff: a didactical model

NASA Astrophysics Data System (ADS)

Borghi, Riccardo; Spinozzi, Turi Maria

2017-07-01

The pedagogical aim of the present paper, thought for an undergraduate audience, is to help students to appreciate how the development of elementary models based on physics first principles is a fundamental and necessary preliminary step for the behaviour of complex real systems to be grasped with minimal amounts of math. In some particularly fortunate cases, such models also show reasonably good results when are compared to reality. The speed behaviour of the Space Shuttle during its first two minutes of flight from liftoff is here analysed from such a didactical point of view. Only the momentum conservation law is employed to develop the model, which is eventually applied to quantitatively interpret the telemetry of the 2011 last launches of Shuttle Discovery and Shuttle Endeavour. To the STS-51-L and STS-107 astronauts, in memoriam.

Perception of Simultaneous Auditive Contents

NASA Astrophysics Data System (ADS)

Tschinkel, Christian

Based on a model of pluralistic music, we may approach an aesthetic concept of music, which employs dichotic listening situations. The concept of dichotic listening stems from neuropsychological test conditions in lateralization experiments on brain hemispheres, in which each ear is exposed to a different auditory content. In the framework of such sound experiments, the question which primarily arises concerns a new kind of hearing, which is also conceivable without earphones as a spatial composition, and which may superficially be linked to its degree of complexity. From a psychological perspective, the degree of complexity is correlated with the degree of attention given, with the listener's musical or listening experience and the level of his appreciation. Therefore, we may possibly also expect a measurable increase in physical activity. Furthermore, a dialectic interpretation of such "dualistic" music presents itself.

Irregular or absent periods--what can an ultrasound scan tell you?

PubMed

Khalid, Asma

2004-02-01

Transvaginal ultrasonography has increased our appreciation of the physiological changes in the ovary and endometrium that occur during the normal menstrual cycle. It has become a primary investigative tool in women with irregular or absent periods. Its usefulness in cases of primary amenorrhoea to assess anatomy is also undisputed although it may have limitations in terms of its specificity. However, the interpretation of ultrasound images in women with irregular menses or secondary amenorrhoea is not entirely straightforward. This is particularly true in the diagnosis of polycystic ovary syndrome, a condition of uncertain aetiology, which may present with oligoamenorrhoea. This chapter aims to discuss the benefits and limitations of ultrasound while taking into account the broad overlap between normal and abnormal physiology, some of which has still to be elucidated.

Jung and the Kabbalah.

PubMed

Drob, S L

1999-05-01

Jung's use of Kabbalistic symbols and ideas as well as his personal Kabbalistic vision are critically examined. It is argued that as great as Jung's acknowledged affinity is to the Kabbalah, his unacknowledged relationship was even greater. Jung has been accused of being a contemporary Gnostic; however, the interpretations Jung placed on Gnosticism and the texts Jung referred to on alchemy were profoundly Kabbalistic, so much so that one would be more justified in calling the Jung of the Mysterium Coniunctionis and other late works a Kabbalist in contemporary guise. Although Jung, at least during the 1930s, appears to have had powerful motives that limited his receptivity to Jewish ideas, his highly ambivalent and at times reproachable attitude toward Judaism should not prevent one from appreciating the affinities between Jungian psychology and Jewish mystical thought.

Somatic and cognitive domains of depression in an underserved region of Ecuador: some cultural considerations

PubMed Central

YUSIM, ANNA; ANBARASAN, DEEPTI; HALL, BRIAN; GOETZ, RAY; NEUGEBAUER, RICHARD; RUIZ, PEDRO

2009-01-01

Not enough research efforts on depression have been carried out up to now in Latin America. The knowledge that has resulted from research activities in the United States or Europe offers limited generalizability to other regions of the world, including Latin America. In the Andean highlands of Ecuador, we found very high rates of moderate and severe depressive symptoms, a finding that must be interpreted within its cultural context. Somatic manifestations of depression predominated over cognitive manifestations, and higher education level was protective against depression. These findings call for an appreciation of culturally-specific manifestations of depression and the social factors that influence them. These factors must be further studied in order to give them the deserved priority, allocate resources appropriately, and formulate innovative psychosocial interventions. PMID:19812756

Using a Virtual Tablet Machine to Improve Student Understanding of the Complex Processes Involved in Tablet Manufacturing.

PubMed

Mattsson, Sofia; Sjöström, Hans-Erik; Englund, Claire

2016-06-25

Objective. To develop and implement a virtual tablet machine simulation to aid distance students' understanding of the processes involved in tablet production. Design. A tablet simulation was created enabling students to study the effects different parameters have on the properties of the tablet. Once results were generated, students interpreted and explained them on the basis of current theory. Assessment. The simulation was evaluated using written questionnaires and focus group interviews. Students appreciated the exercise and considered it to be motivational. Students commented that they found the simulation, together with the online seminar and the writing of the report, was beneficial for their learning process. Conclusion. According to students' perceptions, the use of the tablet simulation contributed to their understanding of the compaction process.

Using a Virtual Tablet Machine to Improve Student Understanding of the Complex Processes Involved in Tablet Manufacturing

PubMed Central

Sjöström, Hans-Erik; Englund, Claire

2016-01-01

Objective. To develop and implement a virtual tablet machine simulation to aid distance students’ understanding of the processes involved in tablet production. Design. A tablet simulation was created enabling students to study the effects different parameters have on the properties of the tablet. Once results were generated, students interpreted and explained them on the basis of current theory. Assessment. The simulation was evaluated using written questionnaires and focus group interviews. Students appreciated the exercise and considered it to be motivational. Students commented that they found the simulation, together with the online seminar and the writing of the report, was beneficial for their learning process. Conclusion. According to students’ perceptions, the use of the tablet simulation contributed to their understanding of the compaction process. PMID:27402990

Caveats on tomographic images

USGS Publications Warehouse

Foulger, Gillian R.; Panza, Giuliano F.; Artemieva, Irina M.; Bastow, Ian D.; Cammarano, Fabio; Evans, John R.; Hamilton, Warren B.; Julian, Bruce R.; Lustrino, Michele; Thybo, Hans; ,

2013-01-01

Geological and geodynamic models of the mantle often rely on joint interpretations of published seismic tomography images and petrological/geochemical data. This approach tends to neglect the fundamental limitations of, and uncertainties in, seismic tomography results. These limitations and uncertainties involve theory, correcting for the crust, the lack of rays throughout much of the mantle, the difficulty in obtaining the true strength of anomalies, choice of what background model to subtract to reveal anomalies, and what cross-sections to select for publication. The aim of this review is to provide a relatively non-technical summary of the most important of these problems, collected together in a single paper, and presented in a form accessible to non-seismologists. Appreciation of these issues is essential if final geodynamic models are to be robust, and required by the scientific observations.

Humor as aggression: effects of motivation on hostility expressed in humor appreciation.

PubMed

Weinstein, Netta; Hodgins, Holley S; Ostvik-White, Elin

2011-06-01

In 4 studies, the authors examined the hypothesis that relative to primed autonomy motivation, primed control would increase enjoyment of hostile (compared with nonhostile) humor as assessed by self-reported enjoyment and aversiveness and by nonverbal behavior. Results confirmed the hypothesis. Furthermore, initial state hostility moderated the effect such that high-hostility participants who were primed with control motivation especially enjoyed hostile humor. The 2 final studies showed that the effect was mediated by implicit aggression such that the combination of high initial state hostility and control priming led to implicit aggression, which in turn resulted in hostile humor enjoyment. Results are interpreted in terms of the effects of autonomy versus control motivation on intrapersonal self-regulatory processes, which influence interpersonal functioning. 2011 APA, all rights reserved

How Stable is Happiness? Using the STARTS Model to Estimate the Stability of Life Satisfaction.

PubMed

Lucas, Richard E; Donnellan, M Brent

2007-10-01

A common interpretation of existing subjective well-being research is that long-term levels of well-being are almost completely stable. However, few studies have estimated stability and change using appropriate statistical models that can precisely address this question. The STARTS model (Kenny & Zautra, 2001) was used to analyze life satisfaction data from two nationally representative panel studies. Results show that 34-38% of the variance in observed scores is trait variance that does not change. An additional 29-34% can be accounted for by an autoregressive trait that is only moderately stable over time. Thus, although life satisfaction is moderately stable over long periods of time, there is also an appreciable degree of instability that might depend on contextual circumstances.

Multiple dimensions of climate change and their implications for biodiversity.

PubMed

Garcia, Raquel A; Cabeza, Mar; Rahbek, Carsten; Araújo, Miguel B

2014-05-02

The 21st century is projected to witness unprecedented climatic changes, with greater warming often reported for high latitudes. Yet, climate change can be measured in a variety of ways, reflecting distinct dimensions of change with unequal spatial patterns across the world. Polar climates are projected to not only warm, but also to shrink in area. By contrast, today's hot and arid climates are expected to expand worldwide and to reach climate states with no current analog. Although rarely appreciated in combination, these multiple dimensions of change convey complementary information. We review existing climate change metrics and discuss how they relate to threats and opportunities for biodiversity. Interpreting climate change metrics is particularly useful for unknown or poorly described species, which represent most of Earth's biodiversity.

Hypoxia-Inducible Factor Prolyl Hydroxylases are Oxygen Sensors in the Brain

DTIC Science & Technology

2005-03-01

astrocytes. It has been appreciated that increased HIF-1α protein levels are commonly found in several cancer types (Zhong, De Marzo et al. 1999...A 98(17): 9630-5. Zhong, H., A. M. De Marzo , et al. (1999). "Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their...rat brain” Discussion 17-23 Bibliography 24 -31 ix INTRODUCTION Vertebrate cells possess adaptive responses to hypoxia

Have the Cake and Eat It: Ecojustice versus Development? Is It Possible to Reconcile Social and Economic Equity, Ecological Sustainability, and Human Development? Some Implications for Ecojustice Education

ERIC Educational Resources Information Center

Jucker, Rolf

2004-01-01

In this article I argue that it is impossible to look at educational issues before we develop a clear understanding of the dominant ideologies that currently perpetuate unsustainability. Only if we appreciate the pervasiveness and the fallacies of such concepts as "development," "growth," and "progress" within a limited biosphere can we start to…

C.A.D. and ergonomic workstations conception

NASA Astrophysics Data System (ADS)

Keravel, Francine

1986-07-01

Computer Aided Design is able to perform workstation's conception. An ergonomic data could be complete this view and warrant a coherent fiability conception. Complexe form representation machines, anthropometric data and environment factors are allowed to perceive the limit points between humain and new technology situation. Work ability users, safety, confort and human efficiency could be also included. Such a programm with expert system integration will give a complete listing appreciation about workstation's conception.

Enlistment Decisions of Young Men.

DTIC Science & Technology

1985-07-01

14Employment status is not the usual one of employed, unemployed , or out of the labor force but instead indicates currently employed, not currently employed...worker with high firm- specific human capital, so he is less likely to be unemployed during a downturn at the firm. Job matching theory (Mincer and...returns) as well as the value one attaches to greater under- standing or appreciation of the world ( psychic returns). The monetary increment will tend to

Glossary of Terms--Nuclear Weapon Phenomena and Effects

DTIC Science & Technology

1985-02-15

w".: w~*~ combat ineffective. An individual whose injuries are of such nature that he is no longer capable of carrying out his assigned task...significantly harmful result [39]. That dose of ionizing radiation that is not expected to cause appreciable bodily injury to a person at any time during his...art and science of protecting human beings from injury by radia- tion, and promoting better health through beneficial applications of radiation [39

Economic Promises and Challenges of Productive Resources: A Study of Man's Use of Productive Resources over the Ages (From the Stone Age to the Space Age).

ERIC Educational Resources Information Center

Bourbonnais, Mary Kathryn

Research and study of economic discoveries, inventions, improvements, and man's use of natural and human resources and capital goods from the Stone Age to the present helped fifth graders understand and appreciate the foundation and structure of the U.S. economic system and today's standards of living. The year-long study, which was integrated…

Targeting Paclitaxel-Loaded Nanoparticles to Ovarian Cancer

DTIC Science & Technology

2013-05-01

group can react with alkyne functionality ( click chemistry ) being widely used for conjugation purpose by several groups. As reported in the annual... peptide As we began to appreciate that the chemistry of linking Lyp-1 to Nexil was going to be more difficult than anticipated, we turned substantial...Nexil we were unable to show improved efficacy in a lung cancer mode. We have shown that the CPE peptide effectively targets the toxin gelonin to human

Educating for collaborative practice: an interpretation of current achievements and thoughts for future directions.

PubMed

Hudson, Judith Nicky; Croker, Anne

2018-01-01

The Edinburgh Declaration, developed in 1998 as a pledge to alter the character of medical education to more effectively meet the needs of society, included a recommendation to increase the opportunity for joint learning between health and health-related professions, as part of the training for teamwork. This article acknowledges achievements since the Declaration in relation to this recommendation, using an umbrella term for the phenomenon, 'educating for collaborative practice', and presents a perspective framed as a series of questions to encourage reflection on future directions. A literature interpretation, informed by philosophical hermeneutics, was conducted using text sets comprising reports and reviews from a section of the international literature since 1988. The interpretation involved: engaging with meanings as presented in the chosen texts; making iterative returns to the texts to explore emerging understanding; and ensuring parts of our understanding from particular texts were fused with complete understanding of the texts as a whole. A lens of appreciative inquiry facilitated acknowledgement of what has been achieved, while being curious about how it could be. Interpretation of the selected literature revealed notable achievements. Areas for further consideration were identified in relation to three themes: establishing shared understanding AND purpose behind use of terminology; being a conduit AND sharing responsibility for change; exploring ways of doing things AND ensuring ongoing inclusivity. Interpreting the current literature on 'educating for collaborative practice' has generated questions for reflection on how it may be otherwise. Readers are encouraged to embrace the tensions inherent in unanswered questions, providing space for communication, initiative and diversity of thought. An ongoing dialogue with the literature is proposed, asking whether educating students for a collective identity in settings where they are learning for and with patients is likely to advance educating for patient-centred collaborative practice. © 2017 John Wiley & Sons Ltd and The Association for the Study of Medical Education.

BECon: a tool for interpreting DNA methylation findings from blood in the context of brain.

PubMed

Edgar, R D; Jones, M J; Meaney, M J; Turecki, G; Kobor, M S

2017-08-01

Tissue differences are one of the largest contributors to variability in the human DNA methylome. Despite the tissue-specific nature of DNA methylation, the inaccessibility of human brain samples necessitates the frequent use of surrogate tissues such as blood, in studies of associations between DNA methylation and brain function and health. Results from studies of surrogate tissues in humans are difficult to interpret in this context, as the connection between blood-brain DNA methylation is tenuous and not well-documented. Here, we aimed to provide a resource to the community to aid interpretation of blood-based DNA methylation results in the context of brain tissue. We used paired samples from 16 individuals from three brain regions and whole blood, run on the Illumina 450 K Human Methylation Array to quantify the concordance of DNA methylation between tissues. From these data, we have made available metrics on: the variability of cytosine-phosphate-guanine dinucleotides (CpGs) in our blood and brain samples, the concordance of CpGs between blood and brain, and estimations of how strongly a CpG is affected by cell composition in both blood and brain through the web application BECon (Blood-Brain Epigenetic Concordance; https://redgar598.shinyapps.io/BECon/). We anticipate that BECon will enable biological interpretation of blood-based human DNA methylation results, in the context of brain.

[Diabolus, disease, and Nietzsche: considerations and interpretations].

PubMed

Barański, J

2001-01-01

Disease shows its dual nature: it carries suffering and pain, but also means trespassing the sluggish limits of healthy life. This trespassing confirms the distance separating man from nature and, at the same time, confirms man's spirituality. Nietzsche's disease and work support this interpretation, so precisely expressed by Thomas Mann in his novel Doctor Faustus: disease contains the diabolus of human biology and human spirituality.

The "MelArete" Project: Educating Children to the Ethics of Virtue and of Care

ERIC Educational Resources Information Center

Mortari, Luigina; Ubbiali, Marco

2017-01-01

The educative project MelArete proposes an interpretation of ethical education: a form of Education to Virtue Ethics in the light of the philosophy of care. Starting from the ontological assumption that care is prime in life and without it the human being cannot flourish in his/her humanity, the project is based on an interpretation of the…

Transformation of Online Teaching Practices Utilizing Appreciative Inquiry to Enhance the Process of Learning

ERIC Educational Resources Information Center

Johnson, Bruce A.

2010-01-01

The purpose of this case study was to explore the application and outcome of appreciative andragogy as an online instructional strategy for the development of adult learner motivation, engagement, and performance. Appreciative andragogy was an original phrase developed for this study and is an adaptation of appreciative inquiry. The concept of…

Considerations for the Use of Human Participants in Vector Biology Research: A Tool for Investigators and Regulators

PubMed Central

Youngblood, Laura; Bangs, Michael J.; Lavery, James V.; James, Stephanie

2015-01-01

Abstract A thorough search of the existing literature has revealed that there are currently no published recommendations or guidelines for the interpretation of US regulations on the use of human participants in vector biology research (VBR). An informal survey of vector biologists has indicated that issues related to human participation in vector research have been largely debated by academic, national, and local Institutional Review Boards (IRBs) in the countries where the research is being conducted, and that interpretations and subsequent requirements made by these IRBs have varied widely. This document is intended to provide investigators and corresponding scientific and ethical review committee members an introduction to VBR methods involving human participation and the legal and ethical framework in which such studies are conducted with a focus on US Federal Regulations. It is also intended to provide a common perspective for guiding researchers, IRB members, and other interested parties (i.e., public health officials conducting routine entomological surveillance) in the interpretation of human subjects regulations pertaining to VBR. PMID:25700039

The importance of the photosynthetic Gibbs effect in the elucidation of the Calvin-Benson-Bassham cycle.

PubMed

Ebenhöh, Oliver; Spelberg, Stephanie

2018-02-19

The photosynthetic carbon reduction cycle, or Calvin-Benson-Bassham (CBB) cycle, is now contained in every standard biochemistry textbook. Although the cycle was already proposed in 1954, it is still the subject of intense research, and even the structure of the cycle, i.e. the exact series of reactions, is still under debate. The controversy about the cycle's structure was fuelled by the findings of Gibbs and Kandler in 1956 and 1957, when they observed that radioactive 14 CO 2 was dynamically incorporated in hexoses in a very atypical and asymmetrical way, a phenomenon later termed the 'photosynthetic Gibbs effect'. Now, it is widely accepted that the photosynthetic Gibbs effect is not in contradiction to the reaction scheme proposed by CBB, but the arguments given have been largely qualitative and hand-waving. To fully appreciate the controversy and to understand the difficulties in interpreting the Gibbs effect, it is illustrative to illuminate the history of the discovery of the CBB cycle. We here give an account of central scientific advances and discoveries, which were essential prerequisites for the elucidation of the cycle. Placing the historic discoveries in the context of the modern textbook pathway scheme illustrates the complexity of the cycle and demonstrates why especially dynamic labelling experiments are far from easy to interpret. We conclude by arguing that it requires sound theoretical approaches to resolve conflicting interpretations and to provide consistent quantitative explanations. © 2018 The Author(s).

Human prenatal diagnosis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Filkins, K.; Russo, J.F.

Advances in the field of prenatal diagnosis have been rapid during the past decade. Moreover, liberal use of birth control methods and restriction of family size have placed greater emphasis on optimum outcome of each pregnancy. There are many prenatal diagnostic techniques of proven value; the risks, including false negatives and false positives, are known. With the rapid proliferation of new and experimental techniques, many disorders are potential diagnosable or even treatable; however, risk factors are unknown and issues relating to quality control have not been resolved. These problems are readily appreciated in the dramatic new techniques involving recombinant DNA,more » chorion villus sampling, and fetal surgery. Unfortunately, clinicians may not appreciate the difficulties that may also be encountered in the more mundane prenatal diagnostic tests such as ultrasonography or enzymatic testing. The aim of this volume is to clarify and rationalize certain aspects of diagnosis, genetic counseling, and intervention. New and experimental techniques are presented in the light of current knowledge.« less

How could you use the ergonomics 'knowhow' transfer management to enhance human working for sustainable improvements in industrially developing countries?

PubMed

Helali, Faramarz

2012-01-01

This paper describes the different strategic understanding from getting ergonomics intervention programmes' conversations to 'Tip', including minimizing strategies; tipping point strategies; and maximizing strategies from building ergonomics intervention techniques. Those have indicated to different recognitions: 1) when amplification of the 'problem' is necessary; 2) when amplification of the 'tipping point' is necessary, and 3) when amplification of the 'success' is necessary. The practical applications and implications of the ergonomics intervention techniques are drawn from the findings of framing positive questions: 1) what is successful ergonomics intervention technique right now (Appreciative)? 2) What do we need to change for a better future (Imagine)? 3) How do we do this (Design)? 4) Who takes action and with what consequences (Act)? This requires re-framing of the ergonomics intervention techniques in an appreciative way, because of, the future action needs to be inspired by those things that participants feel are worth valuing, worth celebrating and sustaining.

Universal Connection through Art: Role of Mirror Neurons in Art Production and Reception

PubMed Central

Piechowski-Jozwiak, Bartlomiej; Boller, François; Bogousslavsky, Julien

2017-01-01

Art is defined as expression or application of human creative skill and imagination producing works to be appreciated primarily for their aesthetic value or emotional power. This definition encompasses two very important elements—the creation and reception of art—and by doing so it establishes a link, a dialogue between the artist and spectator. From the evolutionary biological perspective, activities need to have an immediate or remote effect on the population through improving survival, gene selection, and environmental adjustment, and this includes art. It may serve as a universal means of communication bypassing time, cultural, ethnic, and social differences. The neurological mechanisms of both art production and appreciation are researched by neuroscientists and discussed both in terms of healthy brain biology and complex neuronal networking perspectives. In this paper, we describe folk art and the issue of symbolic archetypes in psychoanalytic thought as well as offer neuronal mechanisms for art by emphasizing mirror/neurons and the role they play in it. PMID:28475130

Drama as a Tool in Interpretation: Practitioner Perceptions of Its Strengths & Limitations

ERIC Educational Resources Information Center

Adcock, Lynne; Ballantyne, Roy

2007-01-01

Although environmental and heritage interpretation aims to connect humans with their natural and cultural heritage, and has the potential to contribute to a vision of sustainable living, it often falls short of engaging and inspiring its audiences. Some interpreters advocate the use of artistic approaches to create more affective…

The Design of Hand Gestures for Human-Computer Interaction: Lessons from Sign Language Interpreters

PubMed Central

Rempel, David; Camilleri, Matt J.; Lee, David L.

2015-01-01

The design and selection of 3D modeled hand gestures for human-computer interaction should follow principles of natural language combined with the need to optimize gesture contrast and recognition. The selection should also consider the discomfort and fatigue associated with distinct hand postures and motions, especially for common commands. Sign language interpreters have extensive and unique experience forming hand gestures and many suffer from hand pain while gesturing. Professional sign language interpreters (N=24) rated discomfort for hand gestures associated with 47 characters and words and 33 hand postures. Clear associations of discomfort with hand postures were identified. In a nominal logistic regression model, high discomfort was associated with gestures requiring a flexed wrist, discordant adjacent fingers, or extended fingers. These and other findings should be considered in the design of hand gestures to optimize the relationship between human cognitive and physical processes and computer gesture recognition systems for human-computer input. PMID:26028955

Appreciation and Life Satisfaction: Does Appreciation Uniquely Predict Life Satisfaction above Gender, Coping Skills, Self-Esteem, and Positive Affectivity?

ERIC Educational Resources Information Center

Halle, Joshua Solomon

2015-01-01

The primary purpose of this research was to examine whether appreciation explains variance in life satisfaction after controlling for gender, positive affectivity, self-esteem, and coping skills. Two hundred ninety-eight undergraduates went to the informed consent page of the online survey composed of the Appreciation Scale, the Satisfaction With…

Teachers' Guide to Music Appreciation III A and III B in the Senior High School.

ERIC Educational Resources Information Center

Scott, J. Mark; Dawkins, Barbara R.

This guide to music appreciation courses was developed for use in senior high schools in Duval County, Jacksonville, Florida. Music Appreciation III A examines the development of music, from the Gothic period through the Classical period. Music Appreciation III B examines the development of music from the Romantic period through the 1970s.…

Difference in brain activations during appreciating paintings and photographic analogs

PubMed Central

Mizokami, Yoshinori; Terao, Takeshi; Hatano, Koji; Hoaki, Nobuhiko; Kohno, Kentaro; Araki, Yasuo; Kodama, Kensuke; Makino, Mayu; Izumi, Toshihiko; Shimomura, Tsuyoshi; Fujiki, Minoru; Kochiyama, Takanori

2014-01-01

Several studies have investigated neural correlates of aesthetic appreciation for paintings but to date the findings have been heterogeneous. This heterogeneity may be attributed to previous studies’ measurement of aesthetic appreciation of not only the beauty of paintings but also the beauty of motifs of the paintings. In order to better elucidate the beauty of paintings, it seems necessary to compare aesthetic appreciation of paintings and photographic analogs which included corresponding real images. We prepared for famous painters’ pictures and their photographic analogs which were set up to resemble each painting in order to investigate the hypothesis that there exist specific neural correlates associated with the aesthetic appreciation for paintings. Forty-four subjects participated in functional magnetic resonance study which required comparisons of aesthetic appreciation of paintings of still life and landscape versus photographic analogs including corresponding real images of still life and landscape. Bilateral cuneus and the left lingual gyrus were activated in the comparison of aesthetic appreciation of paintings versus photographic analogs. In conclusion, the present findings suggest a possibility of the existence of specific neural correlates associated with the aesthetic appreciation for paintings and that bilateral cuneus and the left lingual gyrus may be involved. PMID:25071508

Empathy, culture and self-humanising: Empathising reduces the attribution of greater humanness to the self more in Japan than Australia.

PubMed

Park, Joonha; Haslam, Nick; Kashima, Yoshi; Norasakkunkit, Vinai

2016-08-01

People tend to ascribe greater humanness to themselves than to others. Previous research has indicated that this "self-humanising" bias is independent of self-enhancement and robust across cultures. The present study examined the possible role of empathy in reducing this bias in Japan (N = 80) and Australia (N = 80). Results showed that unlike Australians, Japanese participants who recalled personal experiences of empathising with others were less likely to self-humanise than those in a neutral condition. The effect of the empathy manipulation was not observed in Australia. The findings suggest that empathy may reduce self-focus and enable perceivers to appreciate the full humanness of others, but this effect may be culturally contingent. © 2015 International Union of Psychological Science.

De Novo Origin of Human Protein-Coding Genes

PubMed Central

Wu, Dong-Dong; Irwin, David M.; Zhang, Ya-Ping

2011-01-01

The de novo origin of a new protein-coding gene from non-coding DNA is considered to be a very rare occurrence in genomes. Here we identify 60 new protein-coding genes that originated de novo on the human lineage since divergence from the chimpanzee. The functionality of these genes is supported by both transcriptional and proteomic evidence. RNA–seq data indicate that these genes have their highest expression levels in the cerebral cortex and testes, which might suggest that these genes contribute to phenotypic traits that are unique to humans, such as improved cognitive ability. Our results are inconsistent with the traditional view that the de novo origin of new genes is very rare, thus there should be greater appreciation of the importance of the de novo origination of genes. PMID:22102831

Can community consciousness be a bad thing? A moderated mediation analysis of heterosexism, mental health, and body appreciation in sexual minority men

PubMed Central

Simpson, Courtney C.; Sutter, Megan; Perrin, Paul B.

2016-01-01

This study examined the connections among heterosexism, mental health, body appreciation, and community consciousness in sexual minority men. Participants (N = 89) completed a national online survey. Simultaneous multiple regression found that heterosexism explained 9.4% of the variance in body appreciation and 25.8% of the variance in mental health; mental health accounted for 28.0% of the variance in body appreciation. Within these models, harassment/rejection heterosexism was a unique positive predictor of mental health and a unique negative predictor of body appreciation; depression was a unique negative predictor of body appreciation. A moderated mediational model found that depression mediated the relationship between harassment/rejection heterosexism and body appreciation, but only in men who endorsed high community consciousness. Intervention research might benefit from helping sexual minority men explore the ways in which body image is affected by heterosexism and mental health, as well as the ways that contemporary Western gay communities might contribute to these connections. PMID:27210047

Can community consciousness be a bad thing? A moderated mediation analysis of heterosexism, mental health and body appreciation in sexual minority men.

PubMed

Simpson, Courtney C; Sutter, Megan; Perrin, Paul B

2016-11-01

This study examined the connections between heterosexism, mental health, body appreciation and community consciousness in sexual minority men (SMM). Participants (n = 89) completed a national online survey. Simultaneous multiple regressions found that heterosexism explained 9.4% of the variance in body appreciation and 25.8% of the variance in mental health; mental health accounted for 28.0% of the variance in body appreciation. Within these models, harassment/rejection heterosexism was a unique positive predictor of mental health problems and a unique negative predictor of body appreciation; depression was a unique negative predictor of body appreciation. A moderated mediational model found that depression mediated the relationship between harassment/rejection heterosexism and body appreciation, but only in men who endorsed high community consciousness. Intervention research might benefit from helping SMM explore the ways in which body image is affected by heterosexism and mental health, as well as the ways that contemporary Western gay communities might contribute to these connections.

Aquinas's account of human embryogenesis and recent interpretations.

PubMed

Eberl, Jason T

2005-08-01

In addressing bioethical issues at the beginning of human life, such as abortion, in vitro fertilization, and embryonic stem cell research, one primary concern regards establishing when a developing human embryo or fetus can be considered a person. Thomas Aquinas argues that an embryo or fetus is not a human person until its body is informed by a rational soul. Aquinas's explicit account of human embryogenesis has been generally rejected by contemporary scholars due to its dependence upon medieval biological data, which has been far surpassed by current scientific research. A number of scholars, however, have attempted to combine Aquinas's basic metaphysical account of human nature with current embryological data to develop a contemporary Thomistic account of a human person's beginning. In this article, I discuss two recent interpretations in which it is argued that a human person does not begin to exist until a fetus has developed a functioning cerebral cortex.

Abortion: Strong's counterexamples fail.

PubMed

Di Nucci, E

2009-05-01

This paper shows that the counterexamples proposed by Strong in 2008 in the Journal of Medical Ethics to Marquis's argument against abortion fail. Strong's basic idea is that there are cases--for example, terminally ill patients--where killing an adult human being is prima facie seriously morally wrong even though that human being is not being deprived of a "valuable future". So Marquis would be wrong in thinking that what is essential about the wrongness of killing an adult human being is that they are being deprived of a valuable future. This paper shows that whichever way the concept of "valuable future" is interpreted, the proposed counterexamples fail: if it is interpreted as "future like ours", the proposed counterexamples have no bearing on Marquis's argument. If the concept is interpreted as referring to the patient's preferences, it must be either conceded that the patients in Strong's scenarios have some valuable future or admitted that killing them is not seriously morally wrong. Finally, if "valuable future" is interpreted as referring to objective standards, one ends up with implausible and unpalatable moral claims.

[The interface of public healthcare with the health of the oceans: proliferation of disease, socio-economic impacts and beneficial relationships].

PubMed

de Moura, Jailson Fulgencio; Cardozo, Marcelo; Belo, Mariana Soares da Silva Peixoto; Hacon, Sandra; Siciliano, Salvatore

2011-08-01

Over the past decades, human activities have had a heavy impact on the marine environment, causing alterations in ecological processes. The relationship between the health of the oceans, human activities and public healthcare is already generally accepted, though the mechanisms involved are still under scientific scrutiny. These relationships include a focus on climate change, toxic algal blooms, microbial and chemical contamination in marine waters and bioinvasion by exotic species. Moreover, there is the beneficial effect of the oceans on human health and wellbeing, such as natural products for the human diet, the development of biomedicine, or simply the satisfaction derived from human recreation, sports and other interactions of humans with oceans. The importance of appreciating the link between public healthcare and the health of the oceans is especially important due to the growing number of people living in coastal areas, mainly in tropical and subtropical regions. The backcloth to this is risk-related human activities that pose a danger to marine environmental health and the increase in the vulnerability of humans and biodiversity and socio-environmental iniquity.

Jelena Krmpotić-Nemanić (1921-2008): contributions to human neuroanatomy.

PubMed

Judas, Milos; Petanjek, Zdravko; Kostović, Ivica

2011-01-01

Jelena Krmpotić-Nemanić (1921-2008) was a world-famous anatomist, internationally distinguished otolaryngologist, a member of the Croatian Academy of Sciences & Arts and appreciated professor at the School of Medicine University of Zagreb. The founding influence in her scientific career came from her mentor Drago Perovid who was a student of Ferdinand Hochstetter, the leading authority in the field of human developmental neuroanatomy and embryology. Such an influence was obviously important in early shaping of the research agenda of Jelena Krmpotić-Nemanić, and it remains important in a long series of studies on developing human telencephalon initiated by Ivica Kostović and his collaborators - with an always present and active support of Jelena Krmpotić-Nemanić. The aim of this mini review is to briefly describe her numerous contributions to the anatomy of the human peripheral and central nervous system.

Evolutionary and ecological forces that shape the bacterial communities of the human gut

PubMed Central

Messer, Jeannette S.; Liechty, Emma R; Vogel, Olivia A.; Chang, Eugene B.

2017-01-01

Since microbes were first described in the mid-1600's, we have come to appreciate that they live all around and within us with both beneficial and detrimental effects on nearly every aspect of our lives. The human gastrointestinal tract is inhabited by a dynamic community of trillions of bacteria that constantly interact with each other and their human host. The acquisition of these bacteria is not stochastic, but determined by circumstance (environment), host rules (genetics, immune state, mucus, etc), and dynamic self-selection among microbes to form stable, resilient communities that are in balance with the host. In this review, we will discuss how these factors lead to formation of the gut bacterial community and influence its interactions with the host. We will also address how gut bacteria contribute to disease and how they could potentially be targeted to prevent and treat a variety of human ailments. PMID:28145439

Nora Volkow: motivated neuroscientist.

PubMed

Volkow, Nora

2004-10-01

Nora Volkow claims to have always been curious about the workings of the human brain. Even as a medical student in her native Mexico, she investigated animal behavior with the ultimate goal of understanding human motivation. Upon completing her medical studies, in the early 80s, she moved to the U.S. to take advantage of emerging neuroimaging technologies, first during her psychiatry residency at New York University and Brookhaven National Laboratory, and then as a faculty member at the University of Texas in Houston. In Houston, Volkow embarked on seminal studies into human drug use and the functioning brain, which she continued to pursue, again at Brookhaven, during the subsequent two decades. Volkow established herself as an eminent researcher and proponent of neuroscience, and her insights into the brain have greatly advanced our appreciation of human behavior and motivation. In 2003, she took up her present position as Director of the National Institute on Drug Abuse.

Comparing associative, statistical, and inferential reasoning accounts of human contingency learning.

PubMed

Pineño, Oskar; Miller, Ralph R

2007-03-01

For more than two decades, researchers have contrasted the relative merits of associative and statistical theories as accounts of human contingency learning. This debate, still far from resolution, has led to further refinement of models within each family of theories. More recently, a third theoretical view has joined the debate: the inferential reasoning account. The explanations of these three accounts differ critically in many aspects, such as level of analysis and their emphasis on different steps within the information-processing sequence. Also, each account has important advantages (as well as critical flaws) and emphasizes experimental evidence that poses problems to the others. Some hybrid models of human contingency learning have attempted to reconcile certain features of these accounts, thereby benefiting from some of the unique advantages of different families of accounts. A comparison of these families of accounts will help us appreciate the challenges that research on human contingency learning will face over the coming years.

Students' experiences with interactivity and learning in a high school physics multimedia distance learning course

NASA Astrophysics Data System (ADS)

Villarreal-Stewart, Irene

The purpose guiding this research has been to learn about and describe the phenomena of interactivity from the learners' perspectives and to learn which of the interactivity affordances and practices were actually used by students and why in the process of learning physics using an interactive multimedia distance learning course system. The bigger purpose behind learning about and describing interactivity has been to gain knowledge and perspective for its instructional design to benefit the learner, the school as curriculum implementer, and instructional media designers to create better products. Qualitative methodology in the interpretivist tradition was used, that is, in-depth interviews and on-site observations, to gain understanding of interactivity from the learners' perspective and to gain understanding of the student learning context impacting and shaping the students' interactivity experiences. NVivo was used to sort, organize and index data. All data were read on three levels: literally, interpretively, and reflexively; and were read comparatively to other perspectives to get descriptions and interpretations that were holistic to the implementation and had potential insight to improve practice for instructional designers, teachers, administrators, specifically to improve the learning experience for students. Site-Specific Findings: Students watched videos, resisted using phone and e-mail, and worked math problems to demonstrate learning, which resulted in very little interactivity, virtually no dialogue about physics, no physical activity, one-way communication, multifaceted dissatisfaction, student need for teacher involvement in the learning enterprise, student appreciation for interactivity, and expressed desire for a real, live teacher. I also found that some students did experience the system as interactive, did experience learner control and self-directed learning, and despite dissatisfaction, liked and appreciated the course. Wider Applications: Interactivity, a design element, requires scaffolding and nurturing in implementation. The variable and changing context of implementation suggests the requirement for its consideration in design work. The study suggests that during implementation the integrity of design as a whole and flexibility within the design are important continuing considerations. Recommendations. (1) implementation supervision by the school district, (2) use of a language and activity-based theory of learning and teaching and (3) dialogic inquiry (Wells, 1999) to continue learning about interactivity.

WHO Meeting on EMF Biological Effects and Standards Harmonization in Asia and Oceania, 22-24 October, 2001, Shilla Hotel, Seoul, Korea

DTIC Science & Technology

2001-10-24

thermoelastic waves in the have been developed in several laboratories. head to stimulate auditory system. This hypothesis has been examined theoretically...country, thus stimulating the study on the EMF influence on human body. In closing, I extend my sincere appreciation to all presenters and...various systems of direct stimulation of nerves and other excitable cells the body, particularly the nervous, endocrine and using electrodes. immune

Women in the Infantry - The Effect on the Moral Domain

DTIC Science & Technology

1992-12-12

the male, the warrior. The first framework investigates the biological, anthropological, and sociological causes of human behavior in groups. The...psychological toll on the infantrymen. Okinawa’s mud drove us to a state of frustration and exasperation bordering on rage . It can be appreciated only by...waited to move out. The cursing and outbursts of rage didn’t seem to help, although ,no one was above it when goaded to the point of desperation and

Insights into Appreciation and Learning Systems

NASA Astrophysics Data System (ADS)

Vickers, Geoffrey

[. . .] I grew to manhood before the FirstWorldWar in an England that took stability for granted and regarded order - national and international - both as a self-regulating process of betterment called progress and also as a field for human design directed to the same end. These two not wholly consistent ideas applied in the political-social, the financial-economic, and the scientific-technological fields; all these fields are regarded as benign partners, the first still the most prized.

The Middle East in 2015: The Impact of Regional Trends in U.S. Strategic Planning

DTIC Science & Technology

2002-07-01

longevity , the activation of a Syrian- Israeli track, or the American election cycle—will eliminate the need to provide economic assistance and investment...to do so. But the movement toward elected, albeit still largely consultative, bodies pioneered by Kuwait has been followed in more modest measure in...The trends described in these chapters reflect an appreciation of demography , the natural laws of economics, history, and the deter- mination of human

Radical behaviorist interpretation: Generating and evaluating an account of consumer behavior.

PubMed

Foxall, G R

1998-01-01

This article considers an approach to the radical behaviorist interpretation of complex human social behavior. The chosen context is consumer psychology, a field currently dominated by cognitive models of purchase and consumption. The nature of operant interpretation is considered, and several levels of operant analysis of complex economic behavior in affluent marketing-oriented economies are developed. Empirical evidence for the interpretation is considered, and a case is made for the qualified use of the hypothetico-deductive method in the appraisal of operant interpretations of complex behaviors.

Radical behaviorist interpretation: Generating and evaluating an account of consumer behavior

PubMed Central

Foxall, Gordon R.

1998-01-01

This article considers an approach to the radical behaviorist interpretation of complex human social behavior. The chosen context is consumer psychology, a field currently dominated by cognitive models of purchase and consumption. The nature of operant interpretation is considered, and several levels of operant analysis of complex economic behavior in affluent marketing-oriented economies are developed. Empirical evidence for the interpretation is considered, and a case is made for the qualified use of the hypothetico-deductive method in the appraisal of operant interpretations of complex behaviors. PMID:22478315

Stories of Family, Stories of Self: Developmental Pathways to Interpretive Thought during Adolescence

ERIC Educational Resources Information Center

McKeough, Anne; Malcolm, Jennifer

2011-01-01

Research has shown that a hallmark of adolescent development is the growing capacity to interpret human intentionality. In this chapter, the authors examine developmental change in this capacity, which they have termed interpretive thought, in two types of stories, family and autobiographical, told by Canadian youth aged ten to seventeen years.…

24 CFR 206.23 - Shared appreciation.

Code of Federal Regulations, 2010 CFR

2010-04-01

...) Additional interest based on net appreciated value. Any mortgage for which the mortgagee has chosen the... balance is greater than the adjusted sales proceeds, the net appreciated value is zero. (4) If there has...

Body appreciation, interest in cosmetic enhancements, and need for uniqueness among U.S. college students.

PubMed

Gillen, Meghan M; Dunaev, Jamie

2017-09-01

The aim of the current study was to examine associations between body appreciation and putative correlates that focus on self-enhancement and self-expression. Students (N=261; mean age=20.16years, SD=3.68; 60.9% female) from a non-residential college in the northeastern United States completed a questionnaire measuring body appreciation, interest in cosmetic enhancements, and need for uniqueness. Individuals with higher body appreciation and African Americans/Blacks reported significantly higher self-attributed need for uniqueness and significantly higher investment in a distinctive appearance. The association between body appreciation and interest in cosmetic enhancements (e.g., hair coloring) was not significant. Results suggest that body appreciation may be linked to a desire to express one's own unique qualities. Copyright © 2017 Elsevier Ltd. All rights reserved.

Relationship between positive mental health and appreciation in Korean individuals.

PubMed

Lim, Young-Jin

2017-06-01

Appreciation is a key component of subjective well-being and may contribute to positive mental health. Few studies have examined relationships between specific aspects of appreciation and the 3 dimensions of positive mental health, and thus, the aim of this study was to identify associations between aspects of appreciation and positive mental health. Appreciation and positive mental health were measured in 266 Korean university students (50% females) using the Appreciation Inventory and the Mental Health Continuum-Short Form. The results obtained showed that Have Focus significantly predicted Emotional Well-being; Have Focus and Loss/Adversity significantly predicted Social Well-being and Have Focus, Expression and Nature/Daily Life significantly predicted Psychological Well-being. The implications of results that might enable positive mental health to be enhanced are discussed. © 2015 International Union of Psychological Science.

Lay concepts in informed consent to biomedical research: the capacity to understand and appreciate risk.

PubMed

Iltis, Ana

2006-08-01

Persons generally must give their informed consent to participate in research. To provide informed consent persons must be given information regarding the study in simple, lay language. Consent must be voluntary, and persons giving consent must be legally competent to consent and possess the capacity to understand and appreciate the information. This paper examines the relationship between the obligation to disclose information regarding risks and the requirement that persons have the capacity to understand and appreciate the information. There has been insufficient attention to the extent to which persons must be able to understand and appreciate study information in order to have their consent deemed valid when the information is provided in simple, lay language. This paper argues that (1) the capacity to understand and appreciate information that should be deemed necessary to give valid consent should be defined by the capacity of the typical, cognitively normal adult and (2) the capacity of the typical, cognitively normal adult to understand and appreciate the concept of risk is limited. Therefore, (3) all things being equal, potential subjects must possess a limited capacity to understand and appreciate risk to be deemed competent to consent to research participation. (4) In some cases investigators ought to require that persons possess a greater than typical capacity to understand and appreciate risk.

A Method for Improved Interpretation of "Spot" Biomarker Data ...

EPA Pesticide Factsheets

A Method for Improved Interpretation of "Spot" Biomarker Data The National Exposure Research Laboratory (NERL) Human Exposure and Atmospheric Sciences Division (HEASD) conducts research in support of EPA mission to protect human health and the environment. HEASD research program supports Goal 1 (Clean Air) and Goal 4 (Healthy People) of EPA strategic plan. More specifically, our division conducts research to characterize the movement of pollutants from the source to contact with humans. Our multidisciplinary research program produces Methods, Measurements, and Models to identify relationships between and characterize processes that link source emissions, environmental concentrations, human exposures, and target-tissue dose. The impact of these tools is improved regulatory programs and policies for EPA.

Human biomonitoring data interpretation and ethics; obstacles or surmountable challenges?

PubMed Central

Sepai, Ovnair; Collier, Clare; Van Tongelen, Birgit; Casteleyn, Ludwine

2008-01-01

The use of human samples to assess environmental exposure and uptake of chemicals is more than an analytical exercise and requires consideration of the utility and interpretation of data as well as due consideration of ethical issues. These aspects are inextricably linked. In 2004 the EC expressed its commitment to the development of a harmonised approach to human biomonitoring (HBM) by including an action in the EU Environment and Health Strategy to develop a Human Biomonitoring Pilot Study. This further underlined the need for interpretation strategies as well as guidance on ethical issues. A workshop held in December 2006 brought together stakeholders from academia, policy makers as well as non-governmental organisations and chemical industry associations to a two day workshop built a mutual understanding of the issues in an open and frank discussion forum. This paper describes the discussion and recommendations from the workshop. The workshop developed key recommendations for a Pan-European HBM Study: 1. A strategy for the interpretation of human biomonitoring data should be developed. 2. The pilot study should include the development of a strategy to integrate health data and environmental monitoring with human biomonitoring data at national and international levels. 3. Communication strategies should be developed when designing the study and evolve as the study continues. 4. Early communication with stakeholders is essential to achieve maximum efficacy of policy developments and facilitate subsequent monitoring. 5. Member states will have to apply individually for project approval from their National Research Ethics Committees. 6. The study population needs to have sufficient information on the way data will be gathered, interpreted and disseminated and how samples will be stored and used in the future (if biobanking) before they can give informed consent. 7. The participants must be given the option of anonymity. This has an impact on follow-up. 8. The pilot study should develop guidelines and best practice for Ethics for pan European studies. In conclusion all participants felt there that there has to be stakeholder involvement in any planned pan-European Human Biomonitoring Study and the format of the workshop was appropriate for such dialogue. PMID:18541067

Comparison of a multimedia simulator to a human model for teaching FAST exam image interpretation and image acquisition.

PubMed

Damewood, Sara; Jeanmonod, Donald; Cadigan, Beth

2011-04-01

This study compared the effectiveness of a multimedia ultrasound (US) simulator to normal human models during the practical portion of a course designed to teach the skills of both image acquisition and image interpretation for the Focused Assessment with Sonography for Trauma (FAST) exam. This was a prospective, blinded, controlled education study using medical students as an US-naïve population. After a standardized didactic lecture on the FAST exam, trainees were separated into two groups to practice image acquisition on either a multimedia simulator or a normal human model. Four outcome measures were then assessed: image interpretation of prerecorded FAST exams, adequacy of image acquisition on a standardized normal patient, perceived confidence of image adequacy, and time to image acquisition. Ninety-two students were enrolled and separated into two groups, a multimedia simulator group (n = 44), and a human model group (n = 48). Bonferroni adjustment factor determined the level of significance to be p = 0.0125. There was no difference between those trained on the multimedia simulator and those trained on a human model in image interpretation (median 80 of 100 points, interquartile range [IQR] 71-87, vs. median 78, IQR 62-86; p = 0.16), image acquisition (median 18 of 24 points, IQR 12-18 points, vs. median 16, IQR 14-20; p = 0.95), trainee's confidence in obtaining images on a 1-10 visual analog scale (median 5, IQR 4.1-6.5, vs. median 5, IQR 3.7-6.0; p = 0.36), or time to acquire images (median 3.8 minutes, IQR 2.7-5.4 minutes, vs. median = 4.5 minutes, IQR = 3.4-5.9 minutes; p = 0.044). There was no difference in teaching the skills of image acquisition and interpretation to novice FAST examiners using the multimedia simulator or normal human models. These data suggest that practical image acquisition skills learned during simulated training can be directly applied to human models. © 2011 by the Society for Academic Emergency Medicine.

International education is a broken field: Can ubuntu education bring solutions?

NASA Astrophysics Data System (ADS)

Piper, Benjamin

2016-02-01

Ubuntu is an African philosophy of human kindness; applying it in the Global South would fundamentally alter the design of the education sector. This essay argues, however, that the field of international educational development is not, in fact, structured to support an education influenced by ubuntu ideals. Specifically, the educational development milieu includes donors, implementers and academicians who do not sufficiently question the power dynamics which underpin education development. This creates a field where the power imbalances between donors and host governments are not interrogated, where development workers place too much faith in their own knowledge rather than that of local education experts, and where development practitioners rarely appreciate the privilege of working in countries which are not their own. An ubuntu education would alter the educational development field in myriad critical ways, a few of which are suggested in this essay. Educational development programmes in universities and intake programmes for implementers and donors should teach officers humility, appreciating existing local talent and expertise. Donor programmes should incentivise reflective practice which formally embeds appreciation for local culture and expertise, thereby supporting structures which help educational development experts to review their metacognitive processes. The field should also dramatically increase the numbers of local, minority and female educational development practitioners and provide more avenues for advancement for those groups. These are activities which are critical to supporting the education development field, but require a fundamental change of attitude by practitioners to ensure the right kind of relationships between the West and the Global South.

The Depersonalization of Sex

ERIC Educational Resources Information Center

Frankl, Viktor E.

1977-01-01

Love is frequently interpreted in a reductionistic way as a mere sublimation of sexual drives and instincts which man shares with all the other animals. Such an interpretation blocks a true understanding of all the various human phenomena. (Author)

Evolutionary anthropology and genes: investigating the genetics of human evolution from excavated skeletal remains.

PubMed

Anastasiou, Evilena; Mitchell, Piers D

2013-10-01

The development of molecular tools for the extraction, analysis and interpretation of DNA from the remains of ancient organisms (paleogenetics) has revolutionised a range of disciplines as diverse as the fields of human evolution, bioarchaeology, epidemiology, microbiology, taxonomy and population genetics. The paper draws attention to some of the challenges associated with the extraction and interpretation of ancient DNA from archaeological material, and then reviews the influence of paleogenetics on the field of human evolution. It discusses the main contributions of molecular studies to reconstructing the evolutionary and phylogenetic relationships between extinct hominins (human ancestors) and anatomically modern humans. It also explores the evidence for evolutionary changes in the genetic structure of anatomically modern humans in recent millennia. This breadth of research has led to discoveries that would never have been possible using traditional approaches to human evolution. Copyright © 2013 Elsevier B.V. All rights reserved.

A proposed framework for the interpretation of biomonitoring data

PubMed Central

Boogaard, Peter J; Money, Chris D

2008-01-01

Biomonitoring, the determination of chemical substances in human body fluids or tissues, is more and more frequently applied. At the same time detection limits are decreasing steadily. As a consequence, many data with potential relevance for public health are generated although they need not necessarily allow interpretation in term of health relevance. The European Centre of Ecotoxicology and Toxicology of Chemicals (ECETOC) formed a dedicated task force to build a framework for the interpretation of biomonitoring data. The framework that was developed evaluates biomonitoring data based on their analytical integrity, their ability to describe dose (toxicokinetics), their ability to relate to effects, and an overall evaluation and weight of evidence analysis. This framework was subsequently evaluated with a number of case studies and was shown to provide a rational basis to advance discussions on human biomonitoring allowing better use and application of this type of data in human health risk assessment. PMID:18541066

Riddle appreciation and reading comprehension in Cantonese-speaking children.

PubMed

Tang, Ivy N Y; To, Carol K S; Weekes, Brendan S

2013-10-01

Inference-making skills are necessary for reading comprehension. Training in riddle appreciation is an effective way to improve reading comprehension among English-speaking children. However, it is not clear whether these methods generalize to other writing systems. The goal of the present study was to investigate the relationship between inference-making skills, as measured by riddle appreciation ability, and reading comprehension performance in typically developing Cantonese-speaking children in the 4th grade. Forty Cantonese-speaking children between the ages of 9;1 (years;months) and 11;0 were given tests of riddle appreciation ability and reading comprehension. Chinese character reading and auditory comprehension abilities were also assessed using tests that had been standardized in Hong Kong. Regression analyses revealed that riddle appreciation ability explained a significant amount of variance in reading comprehension after variance due to character reading skills and auditory comprehension skills were first considered. Orthographic, lexical, morphological, and syntactic riddles were also significantly correlated with reading comprehension. Riddle appreciation ability predicts reading comprehension in Cantonese-speaking 4th-grade children. Therefore, training Cantonese speakers in riddle appreciation should improve their reading comprehension.

In vivo sweat film layer thickness measured with Fourier-domain optical coherence tomography (FD-OCT)

NASA Astrophysics Data System (ADS)

Jonathan, Enock

2008-06-01

While human sweat secretion is accepted as a mechanism by which the body cools off, excessive sweating (hyperhidrosis) is now appreciated as a medical condition and the primary site for diagnosis is the palm of the hand. We propose sweat film layer thickness as a potential clinical diagnostic parameter when screening for excessive sweating. In this preliminary study we demonstrate the usefulness of Fourier-domain optical coherence tomography (FD-OCT) for measurement of sweat film thickness in vivo with micron-scale resolution on the hand of a human volunteer. FD-OCT has a superior image acquisition time and identification of active sweat glands, ducts and pores is also possible.

2009 Epigenetics Gordon Research Conference (August 9 - 14, 2009)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jeanie Lee

Epigenetics refers to the study of heritable changes in genome function that occur without a change in primary DNA sequence. The 2009 Gordon Conference in Epigenetics will feature discussion of various epigenetic phenomena, emerging understanding of their underlying mechanisms, and the growing appreciation that human, animal, and plant health all depend on proper epigenetic control. Special emphasis will be placed on genome-environment interactions particularly as they relate to human disease. Towards improving knowledge of molecular mechanisms, the conference will feature international leaders studying the roles of higher order chromatin structure, noncoding RNA, repeat elements, nuclear organization, and morphogenic evolution. Traditionalmore » and new model organisms are selected from plants, fungi, and metazoans.« less

Induction of polyclonal antibody synthesis by human allogeneic and autologous helper factors

PubMed Central

1979-01-01

Human helper factors were obtained from supernates of 48 h unidirectional allogeneic and autologous mixed lymphocyte reactions. These supernates were shown to induce the production of large amounts of immunoglobulin by tonsillar and peripheral blood mononuclear cells. Abundant polyclonal activation to antibody production occurred in these cultures in the absence of antigenic challenge which was similar in degree to that produced by pokeweed mitogen. This was documented by quantitating plasma cells, specific plaque-forming cells, and secreted immunoglobulin. In addition, the supplementation of companion cultures with sheep erythrocytes resulted in a significant enhancement of the specific plaque-forming cell response without an appreciable change in plasma cell number of secreted Ig. PMID:156242

Experiences of surgical continence management approaches for cloacal anomalies: a qualitative analysis based on 6 women.

PubMed

Liao, L-M; Baker, E; Boyle, M E; Woodhouse, C R J; Creighton, S M

2014-10-01

The aim of this qualitative study was to gain insight into health care experiences of young women diagnosed with cloacal anomalies, with a special focus on continence management. Qualitative analysis of one-to-one interviews. A tertiary center for congenital anomalies of the urogenital tract in London. Six women aged 16 to 24 with cloacal anomalies. Tape-recorded one-to-one semi-stuctured interviews with a skilled interviewer. The taped interviews were transcribed and analyzed verbatim using interpretative phenomenological analysis according to the research question. Organizing themes across all of the accounts were identified. Two organizing themes concerning our research interests are summarized. The first theme Personal Agency in the Hands of Experts focuses on the interviewees' appreciation of their life-saving surgical care and their involvement in treatment decisions. The second theme Compromises and Trade-Offs focuses on what it was like to live with the more traditional versus the more advanced continence methods. Reliability emerged as a key priority in terms of continence treatment outcome. Gratitude may have interfered with the women's honest communications during treatment decision and evaluation consultations. A more developed approach to communication about the complex interventions proposed, founded on a nuanced understanding of users perspectives, can enhance informed decision making about continence management approaches. Despite these specific gaps, the interviewees were appreciative of their care and optimistic about life. Copyright © 2014 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

Introductory Geophysics at Colorado College: A Research-Driven Course

NASA Astrophysics Data System (ADS)

Bank, C.

2003-12-01

Doing research during an undergraduate course provides stimulus for students and instructor. Students learn to appreciate the scientific method and get hands-on experience, while the instructor remains thrilled about teaching her/his discipline. The introductory geophysics course taught at Colorado College is made up of four units (gravity, seismic, resistivity, and magnetic) using available geophysical equipment. Within each unit students learn the physical background of the method, and then tackle a small research project selected by the instructor. Students pose a research question (or formulate a hypothesis), collect near-surface data in the field, process it using personal computers, and analyse it by creating computer models and running simple inversions. Computer work is done using the programming language Matlab, with several pre-coded scripts to make the programming experience more comfortable. Students then interpret the data and answer the question posed at the beginning. The unit ends with students writing a summary report, creating a poster, or presenting their findings orally. First evaluations of the course show that students appreciate the emphasis on field work and applications to real problems, as well as developing and testing their own hypotheses. The main challenge for the instructor is to find feasible projects, given the time constraints of a course and availability of field sites with new questions to answer. My presentation will feature a few projects done by students during the course and will discuss the experience students and I have had with this approach.

Medical humanities as expressive of Western culture.

PubMed

Hooker, Claire; Noonan, Estelle

2011-12-01

In this paper we articulate a growing awareness within the field of the ways in which medical humanities could be deemed expressive of Western cultural values. The authors suggest that medical humanities is culturally limited by a pedagogical and scholarly emphasis on Western cultural artefacts, as well as a tendency to enact an uncritical reliance upon foundational concepts (such as 'patient' and 'experience') within Western medicine. Both these tendencies within the field, we suggest, are underpinned by a humanistic emphasis on appreciative or receptive encounters with 'difference' among patients that may unwittingly contribute to the marginalisation of some patients and healthcare workers. While cultural difference should be acknowledged as a central preoccupation of medical humanities, we argue that the discipline must continue to expand its scholarly and critical engagements with processes of Othering in biomedicine. We suggest that such improvements are necessary in order to reflect the cultural diversification of medical humanities students, and the geographical expansion of the discipline within non-Western and/or non-Anglophone locations.

Dancing Intercorporeality: A Health Humanities Perspective on Dance as a Healing Art.

PubMed

Purser, Aimie

2017-12-20

As a contribution to the burgeoning field of health humanities, this paper seeks to explore the power of dance to mitigate human suffering and reacquaint us with what it means to be human through bringing the embodied practice of dance into dialogue with the work of the French philosopher Maurice Merleau-Ponty. Merleau-Ponty's conceptualisation of subjectivity as embodied and of intersubjectivity as intercorporeality frees us from many of the constraints of Cartesian thinking and opens up a new way of thinking about how dance functions as a healing art through its ability to ground and reconnect us with self, world, and others--with our humanity. It is argued that through a Merleau-Pontian framework, we can come to appreciate the true potential of dance as a positive and deeply humanising experience, demonstrating how expressive arts practice understood through the lens of philosophical theory can open up new dimensions of understanding and experience in relation to well-being and self- (and other-) care.

Development of biomimetic nanocomposites as bone extracellular matrix for human osteoblastic cells.

PubMed

Bhowmick, Arundhati; Mitra, Tapas; Gnanamani, Arumugam; Das, Manas; Kundu, Patit Paban

2016-05-05

Here, we have developed biomimetic nanocomposites containing chitosan, poly(vinyl alcohol) and nano-hydroxyapatite-zinc oxide as bone extracellular matrix for human osteoblastic cells and characterized by Fourier transform infrared spectroscopy, powder X-ray diffraction. Scanning electron microscopy images revealed interconnected macroporous structures. Moreover, in this study, the problem related to fabricating a porous composite with good mechanical strength has been resolved by incorporating 5wt% of nano-hydroxyapatite-zinc oxide into chitosan-poly(vinyl alcohol) matrix; the present composite showed high tensile strength (20.25MPa) while maintaining appreciable porosity (65.25%). These values are similar to human cancellous bone. These nanocomposites also showed superior water uptake, antimicrobial and biodegradable properties than the previously reported results. Compatibility with human blood and pH was observed, indicating nontoxicity of these materials to the human body. Moreover, proliferation of osteoblastic MG-63 cells onto the nanocomposites was also observed without having any negative effect. Copyright © 2016 Elsevier Ltd. All rights reserved.

Affinity for Poetry and Aesthetic Appreciation of Joyful and Sad Poems

PubMed Central

Kraxenberger, Maria; Menninghaus, Winfried

2017-01-01

Artworks with sad and affectively negative content have repeatedly been reported to elicit positive aesthetic appreciation. This topic has received much attention both in the history of poetics and aesthetics as well as in recent studies on sad films and sad music. However, poetry and aesthetic evaluations of joyful and sad poetry have received only little attention in empirical studies to date. We collected beauty and liking ratings for 24 sad and 24 joyful poems from 128 participants. Following previous studies, we computed an integrated measure for overall aesthetic appreciation based on the beauty and liking ratings to test for differences in appreciation between joyful and sad poems. Further, we tested whether readers' judgments are related to their affinity for poetry. Results show that sad poems are rated significantly higher for aesthetic appreciation than joyful poems, and that aesthetic appreciation is influenced by the participants' affinity for poetry. PMID:28119649

Affinity for Poetry and Aesthetic Appreciation of Joyful and Sad Poems.

PubMed

Kraxenberger, Maria; Menninghaus, Winfried

2016-01-01

Artworks with sad and affectively negative content have repeatedly been reported to elicit positive aesthetic appreciation. This topic has received much attention both in the history of poetics and aesthetics as well as in recent studies on sad films and sad music. However, poetry and aesthetic evaluations of joyful and sad poetry have received only little attention in empirical studies to date. We collected beauty and liking ratings for 24 sad and 24 joyful poems from 128 participants. Following previous studies, we computed an integrated measure for overall aesthetic appreciation based on the beauty and liking ratings to test for differences in appreciation between joyful and sad poems. Further, we tested whether readers' judgments are related to their affinity for poetry. Results show that sad poems are rated significantly higher for aesthetic appreciation than joyful poems, and that aesthetic appreciation is influenced by the participants' affinity for poetry.

Okinawa, Japan: Geologic Battleground

NASA Astrophysics Data System (ADS)

Waymack, S. W.; Carrington, M. P.; Harpp, K. S.

2005-12-01

One of our main goals as instructors, particularly in introductory courses, is to impart students with an appreciation of how geology has influenced the course of human events. Despite the apparent accessibility of such topics, communicating this in a lively, relevant, and effective way often proves difficult. We use a series of historical events, the Pacific island hopping campaign of WWII, to engage students in an active, guided inquiry exercise to explore how terrain and the underlying geology of an area can shape historical events. Teams of students are assigned the role of planning either the defense or occupation of Okinawa Island, in the Ryukyu arc, in a theoretical version of the 1945 conflict. Students are given a package of information, including geologic and topographic maps, a list of military resources available to them at the time, and some historical background. Students also have access to "reconnaissance" images, 360o digital panoramas of the landscape of Okinawa, keyed to their maps. Each team has a week to plan their strategies and carry out additional research, which they subsequently bring to the table in the form of a written battle plan. With an instructor as arbiter, teams alternate drawing their maneuvers on a map of the island, to which the other team then responds. This continues one move at a time, until the instructor declares a victor. Throughout the exercise, the instructor guides students through analysis of each strategic decision in light of the island's structure and topography, with an emphasis on the appropriate interpretation of the maps. Students soon realize that an understanding of the island's terrain literally meant the difference between life and death for civilians and military participants alike in 1945. The karst landscape of Okinawa posed unique obstacles to both the Japanese and the American forces, including difficult landing sites, networks of natural caves, and sequences of hills aligned perpendicular to the length of the island and to American troop movement. This unique topography forced innovative tactics ranging from reverse slope defense to "blowtorch and corkscrew" offense in response. During this exercise, students apply their map-reading and interpretation skills, as well as their critical analysis abilities; the historical context, in turn, provides motivation to refine those skills. Sun Tzu wrote that all warfare is based on deception. What we hope to communicate to students with this activity is that much of warfare, and, more broadly, the way humans interact with the world, is inherently and undeniably based on geology.

Constructivist developmental theory is needed in developmental neuroscience

NASA Astrophysics Data System (ADS)

Arsalidou, Marie; Pascual-Leone, Juan

2016-12-01

Neuroscience techniques provide an open window previously unavailable to the origin of thoughts and actions in children. Developmental cognitive neuroscience is booming, and knowledge from human brain mapping is finding its way into education and pediatric practice. Promises of application in developmental cognitive neuroscience rests however on better theory-guided data interpretation. Massive amounts of neuroimaging data from children are being processed, yet published studies often do not frame their work within developmental models—in detriment, we believe, to progress in this field. Here we describe some core challenges in interpreting the data from developmental cognitive neuroscience, and advocate the use of constructivist developmental theories of human cognition with a neuroscience interpretation.

Reconstructing meaning through occupation after the death of a family member: accommodation, assimilation, and continuing bonds.

PubMed

Hoppes, Steve; Segal, Ruth

2010-01-01

Reactions to death have been studied extensively from psychological, behavioral, and physiological perspectives. Occupational adaptation to loss has received scant attention. Qualitative research was undertaken to identify and describe occupational responses in bereavement. The constant comparative approach was used to analyze and interpret the occupational responses. Adaptive strategies of occupational accommodation and assimilation were used after the death of a family member. Desire to sustain bonds with the deceased motivated specific occupational engagements. These occupational responses served to reconstruct meaning after the death of a family member. These findings contribute to understanding adaptation after death by adding an occupational perspective to previous theories. Occupational therapists' abilities to support clients after loss can be enhanced through appreciation of occupational accommodation and assimilation and the role of continuing occupational bonds after the death of a loved one.

A detailed investigation of proposed gas-phase syntheses of ammonia in dense interstellar clouds

NASA Technical Reports Server (NTRS)

Herbst, Eric; Defrees, D. J.; Mclean, A. D.

1987-01-01

The initial reactions of the Herbst and Klemperer (1973) and the Dalgarno (1974) schemes (I and II, respectively) for the gas-phase synthesis of ammonia in dense interstellar clouds were investigated. The rate of the slightly endothermic reaction between N(+) and H2 to yield NH(+) and H (scheme I) under interstellar conditions was reinvestigated under thermal and nonthermal conditions based on laboratory data. It was found that the relative importance of this reaction in synthesizing ammonia is determined by how the laboratory data at low temperature are interpreted. On the other hand, the exothermic reaction between N and H3(+) to form NH2(+) + H (scheme II) was calculated to possess significant activation energy and, therefore, to have a negligible rate coefficient under interstellar conditions. Consequently, this reaction cannot take place appreciably in interstellar clouds.

Does persisting fear sustain catatonia?

PubMed

Fink, M; Shorter, E

2017-11-01

To examine the psychological substrate of catatonia. Reviewing the historical descriptions and explanations of catatonic behaviours by clinicians from its delineation in the 19th century to the present. Patients with catatonia are often haunted by fears and terrors; this has not been widely appreciated, and certainly was lost from view in the days when catatonia was considered a subtype of schizophrenia. The report contributes to resolving a major question in catatonia: is the mind in stupor inactive, as the blank state that we picture in anesthetized patients, or is the mind active, so preoccupied as to exclude all other influences. Persistent fear occupies the mind of catatonic patients. The signs of catatonia are adaptations to persistent fear, akin to tonic immobilization. The relief afforded by sedation supports this interpretation. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Effects of off-axis loading on the tensile behavior of a ceramic-matrix composite

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lynch, C.S.; Evans, A.G.

A 0{degree}/90{degree} ceramic-matrix composite (CMC) comprised of Nicalon fibers in magnesium aluminosilicate (MAS) has been loaded in tension in three orientations relative to the fiber direction: 0, 30, and 45{degree}. The off-axis loaded samples exhibit inelastic deformation at appreciably lower stresses than samples loads at 0{degree}. Matrix cracking governs the inelastic strains in all orientations. But, important differences in the morphologies and sequencing of the cracks account for the differences in the stress levels. Off-axis failure also occurs at substantially lower stresses than on-axis failure. On-axis composite failure is governed by fiber fracture, but off-axis failure involves matrix-crack coalescence. Tomore » facilitate interpretation and modeling of these behaviors, the interface friction and debond stresses have been determined from hysteresis measurements.« less

Is There a Universal Understanding of Vulnerability? Experiences with Russian and Romanian Trainees in Research Ethics

PubMed Central

Loue, Sana; Loff, Bebe

2014-01-01

Vulnerability of participants in research and the provision of special protections for vulnerable research participants are key concepts in research ethics. Despite international consensus requiring special protections for vulnerable research participants, both the concept of vulnerability and the nature and adequacy of strategies to reduce vulnerability remain vague and, consequently, are subject to varying interpretations. We report on observations of the challenges faced in understanding this key concept by 20 Russian and Romanian trainees participating in a one-year M.A. training program in research ethics from 2000 through 2011. We describe how trainees’ understanding of and appreciation for the need for special protections of vulnerable research participants was nurtured. This paper is part of a collection of papers analyzing the Fogarty International Center's International Research Ethics Education and Curriculum Development program. PMID:24384513

Carrier-envelope phase dependence of the directional fragmentation and hydrogen migration in toluene in few-cycle laser fields.

PubMed

Li, Hui; Kling, Nora G; Förg, Benjamin; Stierle, Johannes; Kessel, Alexander; Trushin, Sergei A; Kling, Matthias F; Kaziannis, Spyros

2016-07-01

The dissociative ionization of toluene initiated by a few-cycle laser pulse as a function of the carrier envelope phase (CEP) is investigated using single-shot velocity map imaging. Several ionic fragments, CH3 (+), H2 (+), and H3 (+), originating from multiply charged toluene ions present a CEP-dependent directional emission. The formation of H2 (+) and H3 (+) involves breaking C-H bonds and forming new bonds between the hydrogen atoms within the transient structure of the multiply charged precursor. We observe appreciable intensity-dependent CEP-offsets. The experimental data are interpreted with a mechanism that involves laser-induced coupling of vibrational states, which has been found to play a role in the CEP-control of molecular processes in hydrocarbon molecules, and appears to be of general importance for such complex molecules.

The discovery of viruses: advancing science and medicine by challenging dogma.

PubMed

Artenstein, Andrew W

2012-07-01

The discovery of viruses in the final years of the nineteenth century represented the culmination of two decades of work on tobacco mosaic disease by three botanical scientists. Eventually their discovery led to a paradigm shift in scientific thought, but it took more than 20 years to appreciate its implications because it was inconsistent with the prevailing dogma of the time-Koch's postulates. Although these 'rules' were actually conceived of as guidelines upon which to establish microbial causality and their implementation resulted in many new discoveries, they also had the unintended effect of limiting the interpretation of novel findings. However, by challenging existing dogma through rigorous scientific observation and sheer persistence, the investigators advanced medicine and heralded new areas of discovery. Copyright © 2012 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

Effects of personal experiences on the interpretation of the meaning of colours used in the displays and controls in electric control panels.

PubMed

Lee, Inseok; Hwang, Won-Gue

2015-01-01

A survey was conducted to examine how personal experiences affect the interpretation of the meaning of display and control colours on electric control panels (ECPs). In Korea, the red light on ECPs represents a normal state of operation, while the green light represents a stopped state of operation; this appears to contradict the general stereotypes surrounding these colours. The survey results indicated that the participants who had experience in using ECPs interpreted the colour meaning differently from the other participant group. More than half of the experienced participants regarded the coloured displays and controls as they were designed, while most participants in the other group appeared to interpret the colours in accordance with the stereotypes. It is presumed that accidents related to human errors can occur when non-experienced people use the ECPs, which are easily accessible in many buildings. Practitioner Summary: A survey was conducted to investigate how personal experiences affect the interpretation of the function meanings of coloured lights on electrical control panels. It was found that the interpretation varies according to personal experiences, which can induce accidents related to human errors while operating electrical equipment.

Evolutionary fuzzy modeling human diagnostic decisions.

PubMed

Peña-Reyes, Carlos Andrés

2004-05-01

Fuzzy CoCo is a methodology, combining fuzzy logic and evolutionary computation, for constructing systems able to accurately predict the outcome of a human decision-making process, while providing an understandable explanation of the underlying reasoning. Fuzzy logic provides a formal framework for constructing systems exhibiting both good numeric performance (accuracy) and linguistic representation (interpretability). However, fuzzy modeling--meaning the construction of fuzzy systems--is an arduous task, demanding the identification of many parameters. To solve it, we use evolutionary computation techniques (specifically cooperative coevolution), which are widely used to search for adequate solutions in complex spaces. We have successfully applied the algorithm to model the decision processes involved in two breast cancer diagnostic problems, the WBCD problem and the Catalonia mammography interpretation problem, obtaining systems both of high performance and high interpretability. For the Catalonia problem, an evolved system was embedded within a Web-based tool-called COBRA-for aiding radiologists in mammography interpretation.

Mimicking human expert interpretation of remotely sensed raster imagery by using a novel segmentation analysis within ArcGIS

NASA Astrophysics Data System (ADS)

Le Bas, Tim; Scarth, Anthony; Bunting, Peter

2015-04-01

Traditional computer based methods for the interpretation of remotely sensed imagery use each pixel individually or the average of a small window of pixels to calculate a class or thematic value, which provides an interpretation. However when a human expert interprets imagery, the human eye is excellent at finding coherent and homogenous areas and edge features. It may therefore be advantageous for computer analysis to mimic human interpretation. A new toolbox for ArcGIS 10.x will be presented that segments the data layers into a set of polygons. Each polygon is defined by a K-means clustering and region growing algorithm, thus finding areas, their edges and any lineations in the imagery. Attached to each polygon are the characteristics of the imagery such as mean and standard deviation of the pixel values, within the polygon. The segmentation of imagery into a jigsaw of polygons also has the advantage that the human interpreter does not need to spend hours digitising the boundaries. The segmentation process has been taken from the RSGIS library of analysis and classification routines (Bunting et al., 2014). These routines are freeware and have been modified to be available in the ArcToolbox under the Windows (v7) operating system. Input to the segmentation process is a multi-layered raster image, for example; a Landsat image, or a set of raster datasets made up from derivatives of topography. The size and number of polygons are set by the user and are dependent on the imagery used. Examples will be presented of data from the marine environment utilising bathymetric depth, slope, rugosity and backscatter from a multibeam system. Meaningful classification of the polygons using their numerical characteristics is the next goal. Object based image analysis (OBIA) should help this workflow. Fully calibrated imagery systems will allow numerical classification to be translated into more readily understandable terms. Peter Bunting, Daniel Clewley, Richard M. Lucas and Sam Gillingham. 2014. The Remote Sensing and GIS Software Library (RSGISLib), Computers & Geosciences. Volume 62, Pages 216-226 http://dx.doi.org/10.1016/j.cageo.2013.08.007.

Implementing the 4D cycle of appreciative inquiry in health care: a methodological review.

PubMed

Trajkovski, Suza; Schmied, Virginia; Vickers, Margaret; Jackson, Debra

2013-06-01

To examine and critique how the phases of the 4D cycle (Discovery, Dream, Design, and Destiny) of appreciative inquiry are implemented in a healthcare context. Appreciative inquiry is a theoretical research perspective, an emerging research methodology and a world view that builds on action research, organizational learning, and organizational change. Increasing numbers of articles published provide insights and learning into its theoretical and philosophical underpinnings. Many articles describe appreciative inquiry and the outcomes of their studies; however, there is a gap in the literature examining the approaches commonly used to implement the 4D cycle in a healthcare context. A methodological review following systematic principles. A methodological review was conducted including articles from the inception of appreciative inquiry in 1986 to the time of writing this review in November, 2011. Key database searches included CINAHL, Emerald, MEDLINE, PubMed, PsycINFO, and Scopus. A methodological review following systematic principles was undertaken. Studies were included if they described in detail the methods used to implement the 4D cycle of appreciative inquiry in a healthcare context. Nine qualitative studies met the inclusion criteria. Results highlighted that appreciative inquiry application is unique and varied between studies. The 4D phases were not rigid steps and were adapted to the setting and participants. Overall, participant enthusiasm and commitment were highlighted suggesting appreciative inquiry was mostly positively perceived by participants. Appreciative inquiry provides a positive way forward shifting from problems to solutions offering a new way of practicing in health care and health research. © 2012 Blackwell Publishing Ltd.

The spirituality of human consciousness: a Catholic evaluation of some current neuro-scientific interpretations.

PubMed

McGoldrick, Terence A

2012-09-01

Catholic theology's traditional understanding of the spiritual nature of the human person begins with the idea of a rational soul and human mind that is made manifest in free will--the spiritual experience of the act of consciousness and cause of all human arts. The rationale for this religion-based idea of personhood is key to understanding ethical dilemmas posed by modern research that applies a more empirical methodology in its interpretations about the cause of human consciousness. Applications of these beliefs about the body/soul composite to the theory of evolution and to discoveries in neuroscience, paleoanthropology, as well as to recent animal intelligence studies, can be interpreted from this religious and philosophical perspective, which argues for the human soul as the unifying cause of the person's unique abilities. Free will and consciousness are at the nexus of the mutual influence of body and soul upon one another in the traditional Catholic view, that argues for a spiritual dimension to personality that is on a par with the physical metabolic processes at play. Therapies that affect consciousness are ethically problematic, because of their implications for free will and human dignity. Studies of resilience, as an example, argue for the greater, albeit limited, role of the soul's conscious choices in healing as opposed to metabolic or physical changes to the brain alone.

40 CFR 1508.14 - Human environment.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 33 2011-07-01 2011-07-01 false Human environment. 1508.14 Section 1508.14 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY TERMINOLOGY AND INDEX § 1508.14 Human environment. Human environment shall be interpreted comprehensively to include the natural and...

40 CFR 1508.14 - Human environment.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 34 2013-07-01 2013-07-01 false Human environment. 1508.14 Section 1508.14 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY TERMINOLOGY AND INDEX § 1508.14 Human environment. Human environment shall be interpreted comprehensively to include the natural and...

40 CFR 1508.14 - Human environment.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 34 2012-07-01 2012-07-01 false Human environment. 1508.14 Section 1508.14 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY TERMINOLOGY AND INDEX § 1508.14 Human environment. Human environment shall be interpreted comprehensively to include the natural and...

40 CFR 1508.14 - Human environment.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 33 2014-07-01 2014-07-01 false Human environment. 1508.14 Section 1508.14 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY TERMINOLOGY AND INDEX § 1508.14 Human environment. Human environment shall be interpreted comprehensively to include the natural and...

40 CFR 1508.14 - Human environment.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Human environment. 1508.14 Section 1508.14 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY TERMINOLOGY AND INDEX § 1508.14 Human environment. Human environment shall be interpreted comprehensively to include the natural and...

Appreciating Music: An Active Approach

ERIC Educational Resources Information Center

Levin, Andrew R.; Pargas, Roy P.

2005-01-01

A particularly innovative use of laptops is to enhance the music appreciation experience. Group listening and discussion, in combination with a new Web-based application, lead to deeper understanding of classical music. ["Appreciating Music: An Active Approach" was written with Joshua Austin.

High theory/mass markets: Newsweek magazine and the circuits of medical culture.

PubMed

Lewis, Bradley

2007-01-01

Medicine is driven by much more than science and reason (ethics); it is also driven by the circuits of culture within which it operates. This article examines how postmodern theory deconstructs standard ideals of science and reason and allows medical humanities scholars to better contextualize the world of medicine. As such, postmodern theory provides an invaluable tool for understanding the circuits of popular culture and medicine's place within these circuits. Using a recent issue of Newsweek magazine devoted to health and technology to illustrate the main points, this essay argues that contemporary popular influences on medicine are deeply problematic, and that through an appreciation of the dynamics of culture, medical humanities scholars can join the struggle over medical culture. This perspective allows medical humanities to make important contributions toward alternative circuits of medical representation, consumption, and identification.

Standardised animal models of host microbial mutualism

PubMed Central

Macpherson, A J; McCoy, K D

2015-01-01

An appreciation of the importance of interactions between microbes and multicellular organisms is currently driving research in biology and biomedicine. Many human diseases involve interactions between the host and the microbiota, so investigating the mechanisms involved is important for human health. Although microbial ecology measurements capture considerable diversity of the communities between individuals, this diversity is highly problematic for reproducible experimental animal models that seek to establish the mechanistic basis for interactions within the overall host-microbial superorganism. Conflicting experimental results may be explained away through unknown differences in the microbiota composition between vivaria or between the microenvironment of different isolated cages. In this position paper, we propose standardised criteria for stabilised and defined experimental animal microbiotas to generate reproducible models of human disease that are suitable for systematic experimentation and are reproducible across different institutions. PMID:25492472

Looking and listening for learning in arts- and humanities-based creations.

PubMed

Varpio, Lara; Grassau, Pamela; Hall, Pippa

2017-02-01

The arts and humanities are gradually gaining a foothold in health professions education as a means of supporting the development of future clinicians who are compassionate, critical and reflexive thinkers, while also strengthening clinical skills and practices that emphasise patient-centredness, collaboration and interprofessional practices. Assignments that tap into trainee creativity are increasingly used both to prepare learners for the demands of clinical work and to understand the personal and professional challenges learners face in these contexts. Health professions educators need methods for interpreting these creations in order to understand each learner's expressions. This paper describes two theoretical frameworks that can be used to understand trainees' unique learning experiences as they are expressed in arts- and humanities-based creations. The authors introduce the philosophical underpinnings and interpretation procedures of two theoretical frameworks that enable educators to 'hear' and 'see' the multilayered expressions embedded within arts- and humanities-based student creations: Gilligan's Listening Guide and Kress and van Leeuwen's approach to visual rhetoric. To illustrate how these frameworks can be used, the authors apply them to two creative summaries that learners made as part of a humanities-informed, interprofessional education intervention that took place in a non-acute-care teaching hospital. The interpretations of two creative summaries, a poem and a pair of paintings, highlight how applying these theoretical frameworks can offer important insights into learners' experiences. This cross-cutting edge paper describes how the Listening Guide and visual rhetoric can help health professions educators listen to and read the arts- and humanities-based creative expressions made by learners. Insights gained from these interpretations can advance the understanding of students' personal experiences in different learning environments and can inform curriculum development. © 2016 John Wiley & Sons Ltd and The Association for the Study of Medical Education.

An intervention to improve paediatric and newborn care in Kenyan district hospitals: understanding the context.

PubMed

English, Mike; Ntoburi, Stephen; Wagai, John; Mbindyo, Patrick; Opiyo, Newton; Ayieko, Philip; Opondo, Charles; Migiro, Santau; Wamae, Annah; Irimu, Grace

2009-07-23

It is increasingly appreciated that the interpretation of health systems research studies is greatly facilitated by detailed descriptions of study context and the process of intervention. We have undertaken an 18-month hospital-based intervention study in Kenya aiming to improve care for admitted children and newborn infants. Here we describe the baseline characteristics of the eight hospitals as environments receiving the intervention, as well as the general and local health system context and its evolution over the 18 months. Hospital characteristics were assessed using previously developed tools assessing the broad structure, process, and outcome of health service provision for children and newborns. Major health system or policy developments over the period of the intervention at a national level were documented prospectively by monitoring government policy announcements, the media, and through informal contacts with policy makers. At the hospital level, a structured, open questionnaire was used in face-to-face meetings with senior hospital staff every six months to identify major local developments that might influence implementation. These data provide an essential background for those seeking to understand the generalisability of reports describing the intervention's effects, and whether the intervention plausibly resulted in these effects. Hospitals had only modest capacity, in terms of infrastructure, equipment, supplies, and human resources available to provide high-quality care at baseline. For example, hospitals were lacking between 30 to 56% of items considered necessary for the provision of care to the seriously ill child or newborn. An increase in spending on hospital renovations, attempts to introduce performance contracts for health workers, and post-election violence were recorded as examples of national level factors that might influence implementation success generally. Examples of factors that might influence success locally included frequent and sometimes numerous staff changes, movements of senior departmental or administrative staff, and the presence of local 'donor' partners with alternative priorities. The effectiveness of interventions delivered at hospital level over periods realistically required to achieve change may be influenced by a wide variety of factors at national and local levels. We have demonstrated how dynamic such contexts are, and therefore the need to consider context when interpreting an intervention's effectiveness.

Appreciation and implementation of the Krachtvoer healthy diet promotion programme for 12- to 14- year-old students of prevocational schools

PubMed Central

2011-01-01

Background Krachtvoer is a school-based healthy diet programme, developed in 2001 and revised in 2007 to meet the needs of particular segments of the target population as well as a wider target group. The main aims of the present process evaluation of the revised programme were to examine student and teacher appreciation of the programme, completeness of and adherence to its implementation, and relations between appreciation and completeness of implementation. Methods Data were collected among 22 teachers and 1117 students of 13 schools, using student evaluation forms, teacher logbooks, telephone interviews, and classroom observations. Results Results indicate favourable levels of teacher and student appreciation for the programme in general and the revised elements. Girls, first-year students and students with more favourable dietary intakes particularly appreciated individual programme elements. Levels of completeness of implementation were high, but several teachers did not adhere to the intended implementation period. Some moderately strong relations were found between teacher appreciation and completeness of implementation scores. Conclusion We conclude that the revisions have resulted in a programme that was appreciated well, also by the extended target group, and was implemented with a high degree of completeness. Teacher appreciation proved potentially important for completeness of implementation. We identified several aspects requiring improvement, indicating the importance of continued programme updates and repeated evaluation. PMID:22151954

Multiple selective events at the PRDM16 functional pathway shaped adaptation of western European populations to different climate conditions.

PubMed

Quagliarello, Andrea; De Fanti, Sara; Giuliani, Cristina; Abondio, Paolo; Serventi, Patrizia; Sarno, Stefania; Sazzini, Marco; Luiselli, Donata

2017-12-30

Several studies highlighted the role of climate in shaping many human evolutionary processes. This occurred even in relatively recent times, having affected various human phenotypic traits, among which metabolic processes that orchestrate absorption and accumulation of substances to maintain energy homeostasis, that is critical for the survival of individuals in high energy-expenditure environments. To date, most researches have focalized on detection of climatic influence on SNPs' frequency in populations exposed to extreme environmental conditions or by comparing variation patterns between populations from different continents. In this study, we instead explored the genetic background of distinct western European human groups at loci involved in nutritional and thermoregulation processes, to test whether patterns of differential local adaptation to environmental conditions could be appreciated also at a lower geographical scale. Taking advantage from the 1000 Genomes Project data, genetic information for 21 genes involved in nutritional and thermoregulation processes was analysed for three western European populations. The applied Anthropological Genetics methods pointed to appreciable differentiation between the examined groups especially for the PRDM16 gene. Moreover, several neutrality tests suggested that balancing selection has acted on different regions of the gene in people from Great Britain, as well as that more recent positive selection could have also targeted some PRDM16 SNPs in Finn and Italian populations. These series of adaptive footprints are plausibly related to climate variability in both ancient and relatively recent times. Since this locus is involved in thermoregulation mechanisms and adipogenesis, local adaptations mediated by a pathway related to the brown adipose tissue activity could have evolved in response to changing cold temperature exposures of such populations.

Diatoms to human uses: linking nitrogen deposition, aquatic eutrophication, and ecosystem services

DOE PAGES

Rhodes, Charles; Bingham, Andrew; Heard, Andrea M.; ...

2017-07-24

Nitrogen (N) loading to aquatic ecosystems can lead to eutrophication, changing the ecosystem within a waterbody, including primary productivity, water clarity, and food web dynamics. Nutrient loading often first affects the primary productivity of aquatic systems through shifts in phytoplankton communities. However, ecologically important changes in phytoplankton are often not relatable to the general public—whose behavior would need to change to alter patterns of nutrient loading. Therefore, we use the STressor–Ecological Production function–final ecosystem Services Framework to develop 154 chains that link changes in biological indicators of aquatic eutrophication (a shift in phytoplankton community) to final ecosystem services that peoplemore » use or appreciate. We identify 13 ecological production functions (EPF) within three different ecosystems (alpine lakes, lakes, and estuaries) that connect changes in phytoplankton and algae to ecological endpoints that the general public and policy makers can appreciate. Using the Final Ecosystem Goods and Services Classification System, we identify 18 classes of human beneficiaries that potentially will be impacted by a change in one of these endpoints. We further assign strength-of-science scores to each link within the EPFs for the 154 chains according to how well each link is supported by current peer-reviewed literature. By identifying many pathways through which excess N loading in U.S. surface waters can affect ecosystems and ultimately the beneficiaries of ecosystem services, this work intends to draw attention to gaps in empirical ecological literature that constrain understanding of the magnitude of effects that excess N loading can have on human well-being. Here, results highlight the importance of intersections between the natural and social sciences when managers and policy makers evaluate impacts from ecological stressors. A balance between knowledgeable specialists proved key to applying this approach and will continue to remain important.« less

Diatoms to human uses: linking nitrogen deposition, aquatic eutrophication, and ecosystem services

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rhodes, Charles; Bingham, Andrew; Heard, Andrea M.

Nitrogen (N) loading to aquatic ecosystems can lead to eutrophication, changing the ecosystem within a waterbody, including primary productivity, water clarity, and food web dynamics. Nutrient loading often first affects the primary productivity of aquatic systems through shifts in phytoplankton communities. However, ecologically important changes in phytoplankton are often not relatable to the general public—whose behavior would need to change to alter patterns of nutrient loading. Therefore, we use the STressor–Ecological Production function–final ecosystem Services Framework to develop 154 chains that link changes in biological indicators of aquatic eutrophication (a shift in phytoplankton community) to final ecosystem services that peoplemore » use or appreciate. We identify 13 ecological production functions (EPF) within three different ecosystems (alpine lakes, lakes, and estuaries) that connect changes in phytoplankton and algae to ecological endpoints that the general public and policy makers can appreciate. Using the Final Ecosystem Goods and Services Classification System, we identify 18 classes of human beneficiaries that potentially will be impacted by a change in one of these endpoints. We further assign strength-of-science scores to each link within the EPFs for the 154 chains according to how well each link is supported by current peer-reviewed literature. By identifying many pathways through which excess N loading in U.S. surface waters can affect ecosystems and ultimately the beneficiaries of ecosystem services, this work intends to draw attention to gaps in empirical ecological literature that constrain understanding of the magnitude of effects that excess N loading can have on human well-being. Here, results highlight the importance of intersections between the natural and social sciences when managers and policy makers evaluate impacts from ecological stressors. A balance between knowledgeable specialists proved key to applying this approach and will continue to remain important.« less

Choline Metabolites: Gene by Diet Interactions

PubMed Central

Smallwood, Tangi; Allayee, Hooman; Bennett, Brian J.

2015-01-01

Purpose of review This review highlights recent advances in our understanding of the interactions between genetic polymorphisms in genes that metabolize choline and the dietary requirements of choline and how these interactions relate to human health and disease. Recent findings The importance of choline as an essential nutrient has been well established but our appreciation of the interaction between our underlying genetic architecture and dietary choline requirements is only beginning. It has been shown in both human and animal studies that choline deficiencies contribute to diseases such as non-alcoholic fatty liver disease and various neurodegenerative diseases. An adequate supply of dietary choline is important for optimum development, highlighted by the increased maternal requirements during fetal development and in breast-fed infants. We discuss recent studies investigating variants in PEMT and MTHFR1 that are associated with a variety of birth defects. In addition to genetic interactions, we discuss several recent studies that uncover changes in fetal global methylation patterns in response to maternal dietary choline intake that result in changes in gene expression in the offspring. In contrast to the developmental role of adequate choline, there is now an appreciation of the role choline has in cardiovascular disease through the gut microbiota-mediated metabolite trimethylamine N-oxide. This pathway highlights some of our understanding of how the microbiome affects nutrient processing and bioavailability. Finally, in order to better characterize the genetic architecture regulating choline requirements, we discuss recent results focused on identifying polymorphisms that regulate choline and its derivative products. Summary Here we discuss recent studies that have advanced our understanding of how specific alleles in key choline metabolism genes are related to dietary choline requirements and human disease. PMID:26655287

Cells and cell biochemistry.

PubMed

Farley, Alistair; Hendry, Charles; McLafferty, Ella

This article, which forms part of the life sciences series, aims to promote understanding of the basic structure and function of cells. It assists healthcare professionals to appreciate the complex anatomy and physiology underpinning the functioning of the human body. Several introductory chemical concepts and terms are outlined. The basic building blocks of all matter, atoms, are examined and the way in which they may interact to form new compounds within the body is discussed. The basic structures and components that make up a typical cell are considered.

Inertial Sensor Characterization for Inertial Navigation and Human Motion Tracking Applications

DTIC Science & Technology

2012-06-01

sensor to the pendulum. The time he took to design this part in SolidWorks so that I could have it printed on a 3D printer was greatly appreciated...I would also like to thank Daniel Sakoda for his quick turnaround in printing the mounting bracket using a 3D printer . Lastly, I would like to...sensors provide three-dimensional ( 3D ) orientation, acceleration, rate of turn, and magnetic field information. Manufacturers specify both static and

Mineral resource of the month: gemstones

USGS Publications Warehouse

Olson, Donald W.

2008-01-01

Humans have been intrigued by gemstones since prehistoric times. Gemstones have been valued as treasured objects throughout history by all societies in all parts of the world. The first stones known to have been used for making jewelry include amber, amethyst, coral, diamond, emerald, garnet, jade, jasper, lapis lazuli, pearl, rock crystal, ruby, serpentine and turquoise. These stones served as status symbols for the wealthy. Today, arguably, gems are worn more for pleasure and in appreciation of their beauty than to demonstrate wealth.