Sample records for approach implicates usf1

  1. Techniques to Improve Ultrasound-Switchable Fluorescence Imaging

    NASA Astrophysics Data System (ADS)

    Kandukuri, Jayanth

    Novel approaches to the improvement of ultrasound-switchable fluorescence (USF) imaging--a relatively new imaging modality that combines ultrasound and optical imaging techniques--have been proposed for early cancer detection. In USF, a high-intensity focused ultrasound (HIFU) beam is used to induce temperature rise within its acoustic focal region due to which a thermo-sensitive USF contrast agent undergoes a switch in its state by increasing the output of fluorescence photons. By using an increase in fluorescence, one can isolate and quantify the fluorescence properties within the ultrasonic focal area. Therefore, USF is able to provide fluorescence contrast while maintaining ultrasound resolution in tissue. The major challenge of the conventional USF technique is its low axial resolution and its sensitivity (i.e. its signal-to-noise ratio (SNR)). This work focuses on investigating and developing a novel USF system design that can improve the resolution and SNR of USF imaging for biological applications. This work can be divided into two major parts: characterizing the performance of a high-intensity focused ultrasound transducer; and improving the axial resolution and sensitivity of the USF technique. Preliminary investigation was conducted by using an IR camera setup to detect temperature variation and thereby study the performance of the high-intensity focused ultrasound transducer to quantify different parameters of ultrasound-induced temperature focal size (UTFS). Investigations are conducted for the purpose of high-resolution imaging with an emphasis on HIFU-induced thermal focus size, short duration of HIFU-induced temperature increase (to avoid thermal diffusion or conduction), and control of HIFU-induced temperature increase within a few degrees Celsius. Next, the focus was shifted to improving the sensitivity of the ultrasound-switchable fluorescence-imaging technique. In this study, the USF signal is encoded with the modulation frequency of the ultrasound by modulating the induced temperature. Later, two approaches were adopted to modify the USF design to improve the resolution of the conventional USF imaging technique. The first approach aims to improve the axial resolution of conventional USF technique, which involves changing the USF system to adopt a dual-HIFU transducer arrangement (in which the transducers are 90 degree with respect to each other) for use as the heating source. The overlapped region of the two crossed foci (OR-TCF) of the dual-HIFU transducer module is expected to have small thermal size along both lateral and axial directions; thus, it could improve the axial resolution of the USF imaging technique. The second approach aims to demonstrate the improvement of resolution via a single-element HIFU transducer with a high frequency (15 MHz). The high frequency of the ultrasound transducer would have smaller acoustic lateral and axial size and should therefore have smaller thermal size. Thus, both approaches should be able to reduce the focal region of heating and thereby improve the resolution of the USF imaging. Results show that the driving power and exposure time of the HIFU transducer significantly influence the ultrasound-induced temperature focal size (UTFS). Interestingly, a nonlinear acoustic effect was observed at certain variations of the ultrasound exposure power while satisfying the thermal confinement within UTFS. This has been shown to reduce UTFS beyond the acoustic diffraction limit, while the ultrasound-induced thermal energy, which is confined within the focal volume, can induce a desired peak-temperature increase of a few degrees. On other hand, after encoding the HIFU exposure and therefore the detected USF signal with a modulation frequency, the SNR (sensitivity) and full width at half maximum (FWHM) along the lateral direction of the USF image was calculated to be 114 and 0.95 mm for a micro-tube with an inner diameter of 0.31 mm (ID), respectively. In comparison, they are 95 and 1.1 mm when using a non-modulated conventional USF imaging technique. In the case of improving the axial resolution of USF imaging for a similar target size, the dual-HIFU USF design was able to achieve 1.07 and 1.5 mm along lateral (x ) and axial (z) directions, respectively. Adopting the second approach of using single 15 MHz HIFU transducer for USF imaging, the axial resolution was calculated to be 0.67+/-0.02 mm and 1.71+/-0.24 mm along lateral (x) and axial (z) directions, respectively. Thus, high-resolution ultrasound-switchable fluorescence with good sensitivity can be designed for biomedical applications.

  2. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dahabieh, Matthew S., E-mail: dahabieh@interchange.ubc.ca; Ooms, Marcel, E-mail: marcel.ooms@mssm.edu; Malcolm, Tom, E-mail: tmalc1@yahoo.com

    Transcription from the HIV-1 long terminal repeat (LTR) is mediated by numerous host transcription factors. In this study we characterized an E-box motif (RBE1) within the core promoter that was previously implicated in both transcriptional activation and repression. We show that RBE1 is a binding site for the RBF-2 transcription factor complex (USF1, USF2, and TFII-I), previously shown to bind an upstream viral element, RBE3. The RBE1 and RBE3 elements formed complexes of identical mobility and protein constituents in gel shift assays, both with Jurkat T-cell nuclear extracts and recombinant USF/TFII-I. Furthermore, both elements are regulators of HIV-1 expression; mutationsmore » in LTR-luciferase reporters and in HIV-1 molecular clones resulted in decreased transcription, virion production, and proviral expression in infected cells. Collectively, our data indicate that RBE1 is a bona fide RBF-2 binding site and that the RBE1 and RBE3 elements are necessary for mediating proper transcription from the HIV-1 LTR.« less

  3. Mapping Historic Gypsy Moth Defoliation with MODIS Satellite Data: Implications for Forest Threat Early Warning System

    NASA Technical Reports Server (NTRS)

    Spurce, Joseph P.; Hargrove, William; Ryan, Robert E.; Smooth, James C.; Prados, Don; McKellip, Rodney; Sader, Steven A.; Gasser, Jerry; May, George

    2008-01-01

    This viewgraph presentation reviews a project, the goal of which is to study the potential of MODIS data for monitoring historic gypsy moth defoliation. A NASA/USDA Forest Service (USFS) partnership was formed to perform the study. NASA is helping USFS to implement satellite data products into its emerging Forest Threat Early Warning System. The latter system is being developed by the USFS Eastern and Western Forest Threat Assessment Centers. The USFS Forest Threat Centers want to use MODIS time series data for regional monitoring of forest damage (e.g., defoliation) preferably in near real time. The study's methodology is described, and the results of the study are shown.

  4. Engaging ranchers in market-based approaches to climate change mitigation: opportunities, challenges, and policy implications

    Treesearch

    Hannah Gosnell; Nicole Robinson-Maness; Susan Charnley

    2011-01-01

    Unsustainable rangeland management and land conversion are significant sources of greenhouse gas emissions and global warming; however, rangelands also can be managed to mitigate climate change by enhancing carbon uptake through increased plant production and biological sequestration. According to a 2000 USFS General Technical Report, there are opportunities to make...

  5. Collaborative implementation for ecological restoration on US public lands: implications for legal context, accountability, and adaptive management

    Treesearch

    William H. Butler; Ashley Monroe; Sarah McCaffrey

    2015-01-01

    The Collaborative Forest Landscape Restoration Program (CFLRP), established in 2009, encourages collaborative landscape scale ecosystem restoration efforts on United States Forest Service (USFS) lands. Although the USFS employees have experience engaging in collaborative planning, CFLRP requires collaboration in implementation, a domain where little prior experience...

  6. Defining Old Growth: Implications For Management

    Treesearch

    David L. White; F. Thomas Lloyd

    1994-01-01

    USDA Forest Service (USFS), with the help of scientists from The Nature Conservancy (TNC), Forest Service Research and ther organizations, is developing old-growth definitions for 35 forest types within the Eastern United States (U.S.). Old-growth forests were officially recognized as a resource by the USFS in 1988 and shortly thereafter, the Eastern Old-Growth...

  7. Differential expression of upstream stimulatory factor (USF) 2 variants in eutopic endometria from women with endometriosis: estradiol regulation.

    PubMed

    Castro, Jazmin; Araya, Germán; Inostroza, Pamela; Hidalgo, Paulina; González-Ramos, Reinaldo; Sovino, Hugo; Boric, M Angélica; Fuentes, Ariel; Johnson, M Cecilia

    2015-10-09

    Endometriosis, pro-inflammatory and invasive benign disease estrogen dependent, abnormally express in endometria the enzyme P450Arom, positively regulated by steroid factor-1 (SF-1). Our objective was to study the nuclear protein contents of upstream stimulating factor 2 (USF2a and USF2b), a positive regulator of SF-1, throughout the menstrual cycle in eutopic endometria from women with and without (control) endometriosis and the involvement of nuclear estrogen receptors (ER) and G-coupled protein estrogen receptor (GPER)-1. Upstream stimulating factor 2 protein contents were higher in mid (USF2b) and late (USF2a and USF2b) secretory phase in eutopic endometria from endometriosis than control (p < 0.05). In isolated control epithelial cells incubated with E2 and PGE2, to resemble the endometriosis condition, the data showed: (a) significant increase of USF2a and USF2b nuclear protein contents when treated with E2, PPT (specific agonist for ERα) or G1 (specific agonist for GPER1); (b) no increase in USF2 binding to SF-1 E-Box/DNA consensus sequence in E2-treated cells; (c) USF2 variants protein contents were not modified by PGE2; (d) SF-1 nuclear protein content was significantly higher than basal when treated with PGE2, E2 or G1, stimulation unaffected by ICI (nuclear ER antagonist); and (e) increased (p < 0.05) cytosolic protein contents of P450Arom when treated with PGE2, E2, PPT or G1 compared to basal, effect that was additive with E2 + PGE2 together. Nevertheless, in endometriosis cells, the high USF2, SF-1 and P450Arom protein contents in basal condition were unmodified. These data strongly suggest that USF2 variants and P450Arom are regulated by E2 through ERα and GPER1, whereas SF-1 through GPER1, visualized by the response of the cells obtained from control endometria, being unaffected the endogenously stimulated cells from endometriosis origin. The lack of E2 stimulation on USF2/SF-1 E-Box/DNA-sequence binding and the absence of PGE2 effect on USF2 variants opposite to the strong induction that they exert on SF1 and P450 proteins suggest different mechanisms and indirect regulations. The sustained USF2 variants protein expression during the secretory phase in eutopic endometria from women with endometriosis may participate in the pathophysiology of this disease strongly associated with infertility and its characteristic endometrial invasion to ectopic sites in the pelvic cavity.

  8. Gender-assortative waist circumference in mother-daughter and father-son pairs, and its implications. An 11-year longitudinal study in children (EarlyBird 59).

    PubMed

    Mostazir, M; Jeffery, A; Voss, L; Wilkin, T

    2014-06-01

    Body mass index (BMI) is reportedly gender assortative (mother-daughter, father-son) in contemporary children. We investigated the corresponding transmission of waist circumference (WC) and its implications. We measured parental WC at baseline and WC, height, weight and para-umbilical skin-fold (USF) annually in their offspring from 5 to 15 years (n = 223 trios). Parents were deemed normal metabolic risk (NR) or high risk (HR) according to World Health Organization (WHO) cut-points for WC (mothers 80 cm, fathers 94 cm). The residual from WC adjusted for BMI (WC|BMI ) was used as a surrogate for excess intra-abdominal fat, and its association with insulin resistance (HOMA2-IR) was sought. WC and USF were both gender assortative, while WC|BMI was not. WC was greater by 1.62 cm (P < 0.05, confidence interval [CI]: 0.09-3.16) and USF by 0.37 cm (P < 0.01, CI: 0.19-0.56) among the daughters (but not the sons) of HR compared with those of NR mothers, and by 1.32 cm (P < 0.05, CI: 0.09-2.55) and 0.18 cm (P < 0.05, CI: 0.04-0.32), respectively in the corresponding father-son (but not father-daughter) pairings. No such differences could be demonstrated for WC|BMI . A standard deviation score 1(SDS) change in WC|BMI , independent of BMI, was associated with a 7.14% change in IR in girls (P < 0.01, CI: 1.76-12.80) and 8.02% in boys (P < 0.001, CI: 2.93-13.36), but there was no relationship between IR and USF. The relationship of offspring WC to metabolic health and to parental size is complex. Subcutaneous abdominal fat is gender assortative but harmless, while intra-abdominal fat (its surrogate in this analysis) is unrelated to parental waist circumference, but metabolically harmful. © 2013 The Authors. Pediatric Obesity © 2013 International Association for the Study of Obesity.

  9. Phosphorylation-dependent down-regulation of apolipoprotein A5 by insulin

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nowak, Maxine; Helleboid-Chapman, Audrey; Jakel, Heidelinde

    2004-02-15

    The apolipoprotein A5 (APOA5) gene has been shown to be important in lowering plasma triglyceride levels. Since several studies have shown that hyperinsulinemia is associated with hypertriglyceridemia, we sought to determine whether APOA5 gene is regulated by insulin. We show here that cell and mouse treatments with insulin down-regulated APOA5 expression in a dose-dependent manner. Furthermore, we determined that insulin decreases APOA5 promoter activity and subsequent deletion analyses revealed an E-box-containing fragment. We showed that Upstream Stimulatory Factors, USF1/USF2, bind to the identified E-box in the APOA5 promoter. Moreover, in cotransfection studies, USF1 stimulates APOA5 promoter activity. The treatment withmore » insulin reduces the binding of USF1/USF2 to APOA5 promoter. The inhibition of PI3K pathway with wortmannin abolished the insulin s effect on APOA5 gene transcription. Using oligoprecipitation method of USF from nuclear extracts, we demonstrated that phosphorylated USF1 failed to bind to APOA5 promoter. This indicates that the APOA5 gene transrepression by insulin involves a phosphorylation of USF through PI3K, that modulate their binding to APOA5 promoter and results in APOA5 down-regulation. The effect of exogenous hyperinsulinemia in healthy men shows a decrease of the plasma ApoAV level. These data suggest a potential mechanism involving APOA5 gene in hypertriglyceridemia associated with hyperinsulinemia.« less

  10. CpG methylation at the USF binding site mediates cell-specific transcription of human ascorbate transporter SVCT2 exon 1a

    PubMed Central

    Qiao, Huan; May, James M.

    2013-01-01

    SVCT2 is the major transporter mediating vitamin C uptake in most organs. Its expression is driven by two promoters (CpG-poor exon 1a promoter and CpG-rich exon 1b promoter). In this work we mapped discrete elements within the proximal CpG-poor promoter responsible for the exon 1a transcription. We identified two E boxes for USF binding and one Y box for NF-Y binding. We further show that the formation of an NFY/USF complex on the exon 1a promoter amplifies each other's ability to bind to the promoter in a cooperativity-dependent manner and is absolutely required for the full activity of the exon 1a promoter. The analysis of the CpG site located at the upstream USF binding site in the promoter showed a strong correlation between expression and demethylation. It was also shown that the exon 1a transcription was induced in cell culture treated with demethylating agent decitabine. The specific methylation of this CpG site impaired both the binding of USF and the formation of the functional NF-Y/USF complex as well as promoter activity, suggesting its importance for the cell-specific transcription. Thus CpG methylation at the upstream USF binding site functions in establishing and maintaining cell-specific transcription from the CpG-poor SVCT2 exon 1a promoter. PMID:21770893

  11. Regulation of IL-10 expression by upstream stimulating factor (USF-1) in glioma-associated microglia.

    PubMed

    Zhang, Leying; Handel, Michelle Van; Schartner, Jill M; Hagar, Aaron; Allen, Grant; Curet, Marjorie; Badie, Behnam

    2007-03-01

    Understanding the local CNS immune response to neoplasms is essential in the development of immune-based treatments for malignant brain tumors. Using rodent glioma models, we have recently found tumor-associated microglia/macrophages (MG/MP) to be less responsive to known MG/MP activators such as CpG, LPS and IFN-gamma. To understand the mechanism of MG/MP suppression, nuclear extracts from rodent intracranial C6 gliomas, C6 glioma-associated MG/MP, normal brain, and normal MG/MP were obtained and studied using Electrophoretic Mobility Shift Assay (EMSA). Among the nuclear factors studied (AP-1, IRF, USF-1 and Stat-1) only USF-1, which is constitutively expressed in most cells, was down-regulated in tumor-associated MG/MP, but not normal MG/MP. Because tumor-associated MG/MP had higher expression of IL-10 (but not TNF-alpha or TGF-beta), we evaluated the role of USF-1 on IL-10 expression. siRNA mediated inhibition of USF-1 expression in primary MG/MP cultures resulted in up-regulation of IL-10 mRNA but not TNF-alpha or TGF-beta. These findings suggest that USF-1 may play a role in IL-10 regulation in MG/MP in brain tumors.

  12. University of South Florida System Annual Accountability Report, 2013-14

    ERIC Educational Resources Information Center

    Board of Governors, State University System of Florida, 2014

    2014-01-01

    This statistical report provides data tables on the University of South Florida System's (USF's) financial resources, personnel, enrollment, undergraduate education, graduate education, and research & economic development. Highlights of USF's achievements in the 2013-2014 academic year include: (1) In Tampa, USF celebrated its strongest…

  13. 76 FR 80941 - Request for Connect America Fund Cost Models

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-27

    ... interested parties to submit forward-looking cost models, consistent with the USF/ICC Transformation Order... forward-looking cost model consistent with the USF/ICC Transformation Order no later than December 30.... SUPPLEMENTARY INFORMATION: 1. On November 18, 2011, the Commission released the USF/ICC Transformation Order, 76...

  14. STAT3 or USF2 Contributes to HIF Target Gene Specificity

    PubMed Central

    Pawlus, Matthew R.; Wang, Liyi; Murakami, Aya; Dai, Guanhai; Hu, Cheng-Jun

    2013-01-01

    The HIF1- and HIF2-mediated transcriptional responses play critical roles in solid tumor progression. Despite significant similarities, including their binding to promoters of both HIF1 and HIF2 target genes, HIF1 and HIF2 proteins activate unique subsets of target genes under hypoxia. The mechanism for HIF target gene specificity has remained unclear. Using siRNA or inhibitor, we previously reported that STAT3 or USF2 is specifically required for activation of endogenous HIF1 or HIF2 target genes. In this study, using reporter gene assays and chromatin immuno-precipitation, we find that STAT3 or USF2 exhibits specific binding to the promoters of HIF1 or HIF2 target genes respectively even when over-expressed. Functionally, HIF1α interacts with STAT3 to activate HIF1 target gene promoters in a HIF1α HLH/PAS and N-TAD dependent manner while HIF2α interacts with USF2 to activate HIF2 target gene promoters in a HIF2α N-TAD dependent manner. Physically, HIF1α HLH and PAS domains are required for its interaction with STAT3 while both N- and C-TADs of HIF2α are involved in physical interaction with USF2. Importantly, addition of functional USF2 binding sites into a HIF1 target gene promoter increases the basal activity of the promoter as well as its response to HIF2+USF2 activation while replacing HIF binding site with HBS from a HIF2 target gene does not change the specificity of the reporter gene. Importantly, RNA Pol II on HIF1 or HIF2 target genes is primarily associated with HIF1α or HIF2α in a STAT3 or USF2 dependent manner. Thus, we demonstrate here for the first time that HIF target gene specificity is achieved by HIF transcription partners that are required for HIF target gene activation, exhibit specific binding to the promoters of HIF1 or HIF2 target genes and selectively interact with HIF1α or HIF2α protein. PMID:23991099

  15. University of South Florida Libraries Search Committee Procedure Handbook.

    ERIC Educational Resources Information Center

    Heilos, Lawrence J.; And Others

    This handbook of procedures developed by the Committee on Professional Concerns (COPC) of the University of South Florida (USF) describes the process to be used in recruiting and hiring qualified candidates for positions on the USF library faculty. The publication is divided into six sections: (1) information on the USF equal employment…

  16. New generation ICG-based contrast agents for ultrasound-switchable fluorescence imaging

    PubMed Central

    Yu, Shuai; Cheng, Bingbing; Yao, Tingfeng; Xu, Cancan; Nguyen, Kytai T.; Hong, Yi; Yuan, Baohong

    2016-01-01

    Recently, we developed a new technology, ultrasound-switchable fluorescence (USF), for high-resolution imaging in centimeter-deep tissues via fluorescence contrast. The success of USF imaging highly relies on excellent contrast agents. ICG-encapsulated poly(N-isopropylacrylamide) nanoparticles (ICG-NPs) are one of the families of the most successful near-infrared (NIR) USF contrast agents. However, the first-generation ICG-NPs have a short shelf life (<1 month). This work significantly increases the shelf life of the new-generation ICG-NPs (>6 months). In addition, we have conjugated hydroxyl or carboxyl function groups on the ICG-NPs for future molecular targeting. Finally, we have demonstrated the effect of temperature-switching threshold (Tth) and the background temperature (TBG) on the quality of USF images. We estimated that the Tth of the ICG-NPs should be controlled at ~38–40 °C (slightly above the body temperature of 37 °C) for future in vivo USF imaging. Addressing these challenges further reduces the application barriers of USF imaging. PMID:27775014

  17. Forest Service Groundwater Plan Oversteps Bounds, Critics Say

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2014-09-01

    The U.S. Forest Service (USFS) is at odds with some members of Congress and other critics about a proposed government directive on groundwater resource management. The USFS says the proposed directive is an innocuous internal measure to provide a consistent, systematic, and transparent agency-wide approach to groundwater management. However, some participants in a 10 September congressional hearing questioned the directive, saying that the agency is overstepping its bounds.

  18. 5-Hydroxymethylcytosine in E-box motifs ACAT|GTG and ACAC|GTG increases DNA-binding of the B-HLH transcription factor TCF4.

    PubMed

    Khund-Sayeed, Syed; He, Ximiao; Holzberg, Timothy; Wang, Jun; Rajagopal, Divya; Upadhyay, Shriyash; Durell, Stewart R; Mukherjee, Sanjit; Weirauch, Matthew T; Rose, Robert; Vinson, Charles

    2016-09-12

    We evaluated DNA binding of the B-HLH family members TCF4 and USF1 using protein binding microarrays (PBMs) containing double-stranded DNA probes with cytosine on both strands or 5-methylcytosine (5mC) or 5-hydroxymethylcytosine (5hmC) on one DNA strand and cytosine on the second strand. TCF4 preferentially bound the E-box motif (CAN|NTG) with strongest binding to the 8-mer CAG|GTGGT. 5mC uniformly decreases DNA binding of both TCF4 and USF1. The bulkier 5hmC also inhibited USF1 binding to DNA. In contrast, 5hmC dramatically enhanced TCF4 binding to E-box motifs ACAT|GTG and ACAC|GTG, being better bound than any 8-mer containing cytosine. Examination of X-ray structures of the closely related TCF3 and USF1 bound to DNA suggests TCF3 can undergo a conformational shift to preferentially bind to 5hmC while the USF1 basic region is bulkier and rigid precluding a conformation shift to bind 5hmC. These results greatly expand the regulatory DNA sequence landscape bound by TCF4.

  19. Genetic Association and Interaction Analysis of USF1 and APOA5 on Lipid Levels and Atherosclerosis

    PubMed Central

    Laurila, Pirkka-Pekka; Naukkarinen, Jussi; Kristiansson, Kati; Ripatti, Samuli; Kauttu, Tuuli; Silander, Kaisa; Salomaa, Veikko; Perola, Markus; Karhunen, Pekka J.; Barter, Philip J.; Ehnholm, Christian; Peltonen, Leena

    2011-01-01

    Objective USF1 is a ubiquitous transcription factor governing the expression of numerous genes of lipid and glucose metabolism. APOA5 is a well-established candidate gene regulating triglyceride (TG) levels and has been identified as a downstream target of upstream stimulatory factor. No detailed studies about the effect of APOA5 on atherosclerotic lesion formation have been conducted, nor has its potential interaction with USF1 been examined. Methods and Results We analyzed allelic variants of USF1 and APOA5 in families (n=516) ascertained for atherogenic dyslipidemia and in an autopsy series of middle-aged men (n=300) with precise quantitative measurements of atherosclerotic lesions. The impact of previously associated APOA5 variants on TGs was observed in the dyslipidemic families, and variant rs3135506 was associated with size of fibrotic aortic lesions in the autopsy series. The USF1 variant rs2516839, associated previously with atherosclerotic lesions, showed an effect on TGs in members of the dyslipidemic families with documented coronary artery disease. We provide preliminary evidence of gene-gene interaction between these variants in an autopsy series with a fibrotic lesion area in the abdominal aorta (P=0.0028), with TGs in dyslipidemic coronary artery disease subjects (P=0.03), and with high-density lipoprotein cholesterol (P=0.008) in a large population cohort of coronary artery disease patients (n=1065) in which the interaction for TGs was not replicated. Conclusion Our findings in these unique samples reinforce the roles of APOA5 and USF1 variants on cardiovascular phenotypes and suggest that both genes contribute to lipid levels and aortic atherosclerosis individually and possibly through epistatic effects. PMID:19910639

  20. Glucose Regulates the Expression of the Apolipoprotein A5 Gene

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fruchart, Jamila; Nowak, Maxime; Helleboid-Chapman, Audrey

    2008-04-07

    The apolipoprotein A5 gene (APOA5) is a key player in determining triglyceride concentrations in humans and mice. Since diabetes is often associated with hypertriglyceridemia, this study explores whether APOA5 gene expression is regulated by alteration in glucose homeostasis and the related pathways. D-glucose activates APOA5 gene expression in a time- and dose-dependent manner in hepatocytes, and the glycolytic pathway involved was determined using D-glucose analogs and metabolites. Together, transient transfections, electrophoretic mobility shift assays and chromatin immunoprecipitation assays show that this regulation occurs at the transcriptional level through an increase of USF1/2 binding to an E-box in the APOA5 promoter.more » We show that this phenomenon is not due to an increase of mRNA or protein expression levels of USF. Using protein phosphatases 1 and 2A inhibitor, we demonstrate that D-glucose regulates APOA5 gene via a dephosphorylation mechanism, thereby resulting in an enhanced USF1/2-promoter binding. Last, subsequent suppressions of USF1/2 and phosphatases mRNA through siRNA gene silencing abolished the regulation. We demonstrate that APOA5 gene is up regulated by D-glucose and USF through phosphatase activation. These findings may provide a new cross talk between glucose and lipid metabolism.« less

  1. The pregnane X receptor down‐regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for (“squelching”) SRC‐1 coactivator

    PubMed Central

    Hyrsova, Lucie; Smutny, Tomas; Carazo, Alejandro; Moravcik, Stefan; Mandikova, Jana; Trejtnar, Frantisek; Gerbal‐Chaloin, Sabine

    2016-01-01

    Background and Purpose The organic cation transporter 1 (OCT1) transports cationic drugs into hepatocytes. The high hepatic expression of OCT1 is controlled by the HNF4α and USF transcription factors. Pregnane X receptor (PXR) mediates induction of the principal xenobiotic metabolizing enzymes and transporters in the liver. Here, we have assessed the down‐regulation of OCT1 expression by PXR activation. Experimental Approach We used primary human hepatocytes and related cell lines to measure OCT1 expression and activity, by assaying MPP+ accumulation. Western blotting, qRT‐PCR, the OCT1 promoter gene reporter constructs and chromatin immunoprecipitation assays were also used. Key Results OCT1 mRNA in human hepatocytes was down‐regulated along with reduced [3H]MPP+ accumulation in differentiated HepaRG cells after treatment with rifampicin. Rifampicin and hyperforin as well as the constitutively active PXR mutant T248D suppressed activity of the 1.8 kb OCT1 promoter construct in gene reporter assays. Silencing of both PXR and HNF4α in HepaRG cells blocked the PXR ligand‐mediated down‐regulation of OCT1 expression. The mutation of HNF4α and USF1 (E‐box) responsive elements reversed the PXR‐mediated inhibition in gene reporter assays. Chromatin immunoprecipitation assays indicated that PXR activation sequestrates the SRC‐1 coactivator from the HNF4α response element and E‐box of the OCT1 promoter. Consistent with these findings, exogenous overexpression of the SRC‐1, but not the PGC1α coactivator, relieved the PXR‐mediated repression of OCT1 transactivation. Conclusions and Implications PXR ligands reduced the HNF4α‐mediated and USF‐mediated transactivation of OCT1 gene expression by competing for SRC‐1 and decreased delivery of a model OCT1 substrate into hepatocytes. PMID:26920453

  2. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zeng, Yanli; Li, Hui; Zhang, Xiaoju

    Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G (APOBEC3G, A3G) exert antiviral defense as an important factor of innate immunity. A variety of cytokines such as IFN-γ,IL2,IL15,IL7 could induce the transcription of A3G. However, the regulation of other nuclear factor on the transcription of A3G have not been reported at the present. To gain new insights into the transcriptional regulation of this restriction factor, we cloned and characterized the promoter region of A3G and investigate the modulation of USF1 gene on the transcription of A3G. We identified a 232 bp region that was sufficient to regulate the activity of full promoter. Transcriptionalmore » start sites (TSS) were identified by the luciferase reporter assays of plasmids containing full or shorter fragments of the A3G promoter. The results demonstrated that the core promoter of A3G is located within the region -159/-84 relative to the TSS. Transcriptional activity of A3G core promoter regulated by USF1 was dependent on an E-box (located at position -91/-86 relative to the major TSS) and was abolished after mutation of this DNA element. USF1 gene can take part in basal transcription regulation of the human A3G gene in hepatocyte, and the identified E-box represented a binding site for the USF1. - Highlights: • The core promoter of A3G is located within the region −159/−84 relative to the TSS. • Transcriptional activity of A3G core promoter regulated by USF1 was dependent on an E-box (located at position −91/−86 relative to the major TSS). • USF1 gene can take part in basal transcription regulation of the human A3G gene in hepatocyte.« less

  3. The rs2516839 Polymorphism of the USF1 Gene May Modulate Serum Triglyceride Levels in Response to Cigarette Smoking

    PubMed Central

    Niemiec, Pawel; Nowak, Tomasz; Iwanicki, Tomasz; Gorczynska-Kosiorz, Sylwia; Balcerzyk, Anna; Krauze, Jolanta; Grzeszczak, Wladyslaw; Wiecha, Maria; Zak, Iwona

    2015-01-01

    Single nucleotide polymorphisms (SNPs) of the USF1 gene (upstream stimulatory factor 1) influence plasma lipid levels. This study aims to determine whether USF1 SNPs interact with traditional risk factors of atherosclerosis to increase coronary artery disease (CAD) risk. In the present study serum lipid levels and USF1 gene polymorphisms (rs2516839 and rs3737787) were determined in 470 subjects: 235 patients with premature CAD and 235 controls. A trend of increasing triglycerides (TG) levels in relation to the C allele dose of rs2516839 SNP was observed. The synergistic effect of cigarette smoking and C allele carrier state on CAD risk was also found (SIM = 2.69, p = 0.015). TG levels differentiated significantly particular genotypes in smokers (1.53 mmol/L for TT, 1.80 mmol/L for CT and 2.27 mmol/L for CC subjects). In contrast, these differences were not observed in the non-smokers subgroup (1.57 mmol/L for TT, 1.46 mmol/L for CT and 1.49 mmol/L for CC subjects). In conclusion, the rs2516839 polymorphism may modulate serum triglyceride levels in response to cigarette smoking. Carriers of the C allele seem to be particularly at risk of CAD, when exposed to cigarette smoking. PMID:26068452

  4. 78 FR 32991 - Connect America Fund

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-03

    ..., 2013. The full text of this document is available for public inspection during regular business hours.... Introduction 1. In the USF/ICC Transformation Order, 76 FR 73830, November 29, 2011, the Commission... the USF/ICC Transformation Order, an unsubsidized competitor in areas where the price cap carrier will...

  5. Introduction [Chapter 1

    Treesearch

    S. Karen Dante-Wood

    2018-01-01

    The Northern Rockies Adaptation Partnership (NRAP) is a science-management partnership among the Forest Service, U.S. Department of Agriculture (USFS) regional offices and national forests (mostly in the Northern Region, and small portions of the Intermountain and Rocky Mountain Regions); USFS Pacific Northwest and Rocky Mountain Research Stations; Glacier, Yellowstone...

  6. Introduction [Chapter 1

    Treesearch

    Joanne J. Ho

    2018-01-01

    The Intermountain Adaptation Partnership (IAP) is a science-management partnership with a wide variety of participants across the U.S. Department of Agriculture Forest Service (USFS) Intermountain Region, which spans Nevada, Utah, southern Idaho, eastern California, and western Wyoming. This USFS region is the largest in the Nation, representing nearly 17 percent of...

  7. Brain in situ hybridization maps as a source for reverse-engineering transcriptional regulatory networks: Alzheimer's disease insights

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Acquaah-Mensah, George K.; Taylor, Ronald C.

    Microarray data have been a valuable resource for identifying transcriptional regulatory relationships among genes. As an example, brain region-specific transcriptional regulatory events have the potential of providing etiological insights into Alzheimer Disease (AD). However, there is often a paucity of suitable brain-region specific expression data obtained via microarrays or other high throughput means. The Allen Brain Atlas in situ hybridization (ISH) data sets (Jones et al., 2009) represent a potentially valuable alternative source of high-throughput brain region-specific gene expression data for such purposes. In this study, Allen BrainAtlasmouse ISH data in the hippocampal fields were extracted, focusing on 508 genesmore » relevant to neurodegeneration. Transcriptional regulatory networkswere learned using three high-performing network inference algorithms. Only 17% of regulatory edges from a network reverse-engineered based on brain region-specific ISH data were also found in a network constructed upon gene expression correlations inmousewhole brain microarrays, thus showing the specificity of gene expression within brain sub-regions. Furthermore, the ISH data-based networks were used to identify instructive transcriptional regulatory relationships. Ncor2, Sp3 and Usf2 form a unique three-party regulatory motif, potentially affecting memory formation pathways. Nfe2l1, Egr1 and Usf2 emerge among regulators of genes involved in AD (e.g. Dhcr24, Aplp2, Tia1, Pdrx1, Vdac1, andSyn2). Further, Nfe2l1, Egr1 and Usf2 are sensitive to dietary factors and could be among links between dietary influences and genes in the AD etiology. Thus, this approach of harnessing brain region-specific ISH data represents a rare opportunity for gleaning unique etiological insights for diseases such as AD.« less

  8. The impact of therapeutic delay time on acute scintigraphic lesion and ultimate scar formation in children with first febrile UTI.

    PubMed

    Oh, Mi Mi; Kim, Jin Wook; Park, Min Gu; Kim, Je Jong; Yoo, Kee Hwan; Moon, Du Geon

    2012-03-01

    We assessed the role of therapeutic delay time (TDT) in acute renal cortical scintigraphic lesion (ASL) and ultimate scar formation (USF) in children with first febrile UTI and whether it is affected by the presence of vesico-ureteral reflux (VUR). 230 children, 90 girls and 140 boys with first febrile UTI were included. Radiologic (USG, DMSA, and VCUG), clinical (age, gender, peak fever, therapeutic delay time) and laboratory (CBC with differential count, ANC (absolute neutrophil count), BUN, Creatinine, urine analysis, gram stain, culture, CRP and ESR) variables were analysed. DMSA was performed within 5 days and after six months. VCUG was performed after acute phase of UTI. The differences in TDT according to the presence of ASL, USF and VUR were assessed. And the correlation between ASL or USF with the duration of TDT was assessed. Of 230 patients enrolled, 142 patients had refluxing UTI and 88 patients had non-refluxing UTI. TDT was the risk factor associated with ASL and USF along with presence of VUR. TDT was longer in ASL positive group compared with the ASL negative group. Also USF group showed longer TDT compared with those without USF in both refluxing UTI and non refluxing UTI. The TDT was significantly shorter in USF group with the presence of VUR. Positive linear association was noted between prevalence of ASL and USF and duration of TDT. In conclusion, the impact of UTI on formation of USF may be enhanced by the presence of VUR with shorter duration of TDT.

  9. Catalyst Bed Instability Within the USFE H2O2/JP-8 Rocket Engine

    NASA Technical Reports Server (NTRS)

    Johnson, Curtis W.; Anderson, William; Ross, Robert; Lyles, G. (Technical Monitor)

    2000-01-01

    Orbital Sciences Corporation has been awarded a contract by NASA's Marshall Space Flight Center, in cooperation with the U.S. Air Force Research Laboratory's Military Space Plane Technology Program Office, for the Upper Stage Flight Experiment (USFE) program. Orbital is designing, developing, and will flight test a new low-cost, 10,000 lbf hydrogen peroxide/ JP-8 pressure fed liquid rocket. During combustion chamber tests at NASA Stennis Space Center (SSC) of the USFE engine, the catalyst bed showed a low frequency instability occurring as the H202 flow reached about 1/3 its design rate. This paper reviews the USFE catalyst bed and combustion chamber and its operation, then discusses the dynamics of the instability. Next the paper describes the dynamic computer model used to recreate the instability. The model was correlated to the SSC test data, and used to investigate possible solutions to the problem. The combustion chamber configuration which solved the instability is shown, and the subsequent stable operation presented.

  10. The transcription factor DREAM represses A20 and mediates inflammation

    PubMed Central

    Tiruppathi, Chinnaswamy; Soni, Dheeraj; Wang, Dong-Mei; Xue, Jiaping; Singh, Vandana; Thippegowda, Prabhakar B.; Cheppudira, Bopaiah P.; Mishra, Rakesh K.; DebRoy, Auditi; Qian, Zhijian; Bachmaier, Kurt; Zhao, Youyang; Christman, John W.; Vogel, Stephen M.; Ma, Averil; Malik, Asrar B.

    2014-01-01

    Here we show that the transcription-repressor DREAM binds to the A20 promoter to repress the expression of A20, the deubiquitinase suppressing inflammatory NF-κB signaling. DREAM-deficient (Dream−/−) mice displayed persistent and unchecked A20 expression in response to endotoxin. DREAM functioned by transcriptionally repressing A20 through binding to downstream regulatory elements (DREs). In contrast, USF1 binding to the DRE-associated E-box domain activated A20 expression in response to inflammatory stimuli. These studies define the critical opposing functions of DREAM and USF1 in inhibiting and inducing A20 expression, respectively, and thereby the strength of NF-κB signaling. Targeting of DREAM to induce USF1-mediated A20 expression is therefore a potential anti-inflammatory strategy in diseases such as acute lung injury associated with unconstrained NF-κB activity. PMID:24487321

  11. USF-related transcription factor, HIV-TF1, stimulates transcription of human immunodeficiency virus-1.

    PubMed

    Maekawa, T; Sudo, T; Kurimoto, M; Ishii, S

    1991-09-11

    The transcription factor HIV-TF1, which binds to a region about 60 bp upstream from the enhancer of the human immunodeficiency virus-1 (HIV-1), was purified from human B cells. HIV-TF1 had a molecular weight of 39,000. Binding of HIV-TF1 to the HIV long terminal repeat (LTR) activated transcription from the HIV promoter in vitro. The HIV-TF1-binding site in HIV LTR was similar to the site recognized by upstream stimulatory factor (USF) in the adenovirus major late promoter. DNA-binding properties of HIV-TF1 suggested that HIV-TF1 might be identical or related to USF. Interestingly, treatment of purified HIV-TF1 by phosphatase greatly reduced its DNA-binding activity, suggesting that phosphorylation of HIV-TF1 was essential for DNA binding. The disruption of HIV-TF1-binding site induced a 60% decrease in the level of transcription from the HIV promoter in vivo. These results suggest that HIV-TF1 is involved in transcriptional regulation of HIV-1.

  12. A Dual-Modality System for Both Multi-Color Ultrasound-Switchable Fluorescence and Ultrasound Imaging

    PubMed Central

    Kandukuri, Jayanth; Yu, Shuai; Cheng, Bingbing; Bandi, Venugopal; D’Souza, Francis; Nguyen, Kytai T.; Hong, Yi; Yuan, Baohong

    2017-01-01

    Simultaneous imaging of multiple targets (SIMT) in opaque biological tissues is an important goal for molecular imaging in the future. Multi-color fluorescence imaging in deep tissues is a promising technology to reach this goal. In this work, we developed a dual-modality imaging system by combining our recently developed ultrasound-switchable fluorescence (USF) imaging technology with the conventional ultrasound (US) B-mode imaging. This dual-modality system can simultaneously image tissue acoustic structure information and multi-color fluorophores in centimeter-deep tissue with comparable spatial resolutions. To conduct USF imaging on the same plane (i.e., x-z plane) as US imaging, we adopted two 90°-crossed ultrasound transducers with an overlapped focal region, while the US transducer (the third one) was positioned at the center of these two USF transducers. Thus, the axial resolution of USF is close to the lateral resolution, which allows a point-by-point USF scanning on the same plane as the US imaging. Both multi-color USF and ultrasound imaging of a tissue phantom were demonstrated. PMID:28165390

  13. Association of USF1 and APOA5 polymorphisms with familial combined hyperlipidemia in an Italian population.

    PubMed

    Di Taranto, Maria Donata; Staiano, Antonino; D'Agostino, Maria Nicoletta; D'Angelo, Antonietta; Bloise, Elena; Morgante, Alberto; Marotta, Gennaro; Gentile, Marco; Rubba, Paolo; Fortunato, Giuliana

    2015-02-01

    Familial combined hyperlipidemia (FCH) is a polygenic and multifactorial disease characterized by a variable phenotype showing increased levels of triglycerides and/or cholesterol. The aim of this study was to identify single nucleotides (SNPs) in lipid-related genes associated with FCH. Twenty SNPs in lipid-related genes were studied in 142 control subjects and 165 FCH patients after excluding patients with mutations in the LDLR gene and patients with the E2/E2 genotype of APOE. In particular, we studied the 9996G > A (rs2073658) and 11235C > T (rs3737787) variants in the Upstream Stimulatory Factor 1 gene (USF1), and the -1131T > C (rs662799) and S19W (rs3135506) variants in the Apolipoprotein A-V gene (APOA5). We found that the frequencies of these variants differed between patients and controls and that are associated with different lipid profiles. At multivariate logistic regression SNP S19W in APOA5 remained significantly associated with FCH independently of age, sex, BMI, cholesterol and triglycerides. Our results show that the USF1 and APOA5 polymorphisms are associated with FCH and that the S19W SNP in the APOA5 gene is associated to the disease independently of total cholesterol, triglycerides and BMI. However, more extensive studies including other SNPs such as rs2516839 in USF1, are required. Copyright © 2014 Elsevier Ltd. All rights reserved.

  14. The USF Libraries Virtual Library Project: A Blueprint for Development.

    ERIC Educational Resources Information Center

    Metz-Wiseman, Monica; Silver, Susan; Hanson, Ardis; Johnston, Judy; Grohs, Kim; Neville, Tina; Sanchez, Ed; Gray, Carolyn

    This report of the Virtual Library Planning Committee (VLPC) is intending to serve as a blueprint for the University of South Florida (USF) Libraries as it shifts from print to digital formats in its evolution into a "Virtual Library". A comprehensive planning process is essential for the USF Libraries to make optimum use of technology,…

  15. What is the best cryopreservation protocol for human testicular tissue banking?

    PubMed

    Baert, Y; Van Saen, D; Haentjens, P; In't Veld, P; Tournaye, H; Goossens, E

    2013-07-01

    Is there a better alternative to the conventional cryopreservation protocols for human testicular tissue banking? Uncontrolled slow freezing (USF) using 1.5 M dimethylsulphoxide (DMSO) and 0.15 M sucrose as cryoprotectants appears to be a user-friendly and efficient method for the cryopreservation of human testicular tissue. Currently, time-consuming controlled slow freezing (CSF) protocols that need expensive equipment are commonly used for human testicular tissue banking. USF and vitrification are cryopreservation techniques that were successfully applied in several animal models but need further exploration with human tissue. Fragments (n = 160) of testicular tissue from 14 patients undergoing vasectomy reversal were assigned to a fresh control group or one of the following cryopreservation procedures: CSF using DMSO at a concentration of 0.7 or 1.5 M in the presence (+S) or absence of sucrose (-S), USF using either 0.7 or 1.5 M DMSO combined with sucrose, solid-surface vitrification (SSV) or direct cover vitrification (DCV). Light microscopic evaluations were performed to study apoptosis, germ cell proliferation ability, spermatogonial survival, coherence of the seminiferous epithelium and integrity of the interstitial compartment after cryopreservation. Ultrastructural alterations were studied by scoring cryodamage to four relevant testicular cell types. The USF 1.5 M DMSO + S protocol proved not solely to prevent cell death and to preserve seminiferous epithelial coherence, interstitial compartment integrity, SG and their potential to divide but also protected the testicular cell ultrastructure. A significant reduction in the number of SG per tubule from 21.4 ± 5.6 in control tissue to 4.9 ± 2.1, 8.2 ± 5.4, 11.6 ± 5.1, 8.8 ± 3.9, 12.6 ± 4.4 and 11.7 ± 5.7 was observed after cryopreservation combined with at least one other form of cryoinjury when using CSF 0.7 M DMSO -S, CSF 0.7 M DMSO + S, CSF 1.5 M DMSO + S, USF 0.7 M DMSO + S, SSV and direct cover vitrification (DCV), respectively (P < 0.001). Supplementary research is required to investigate the effect on tissue functionality and to confirm this study's findings using prepubertal tissue. An optimal cryopreservation protocol enhances the chances for successful fertility restoration. USF, being an easy and cost-effective alternative to CSF, would be preferable for laboratories in developing countries or whenever tissue is to be procured from a diseased child at a site distant from the banking facility.

  16. Crime in woods: role of law enforcement officers in national forests

    Treesearch

    Joanne F. Tynon; Deborah J. Chavez; Joshua W. R. Baur

    2010-01-01

    This first nationwide study of US Forest Service (USFS) law enforcement officers (LEOs) examined respondents’ roles in the USFS, what they perceived as their highest work priority, and what their relationship with the rest of the USFS should be. Results show that LEOs believe they have a high priority for protecting forest users and they believe that National Forest...

  17. Enhancing Ocean Literacy and Expertise of Diverse Populations via Graduate School Fellowship Opportunities

    NASA Astrophysics Data System (ADS)

    Mayo, M.; Ithier-Guzman, W.; Pyrtle, A. J.; Betzer, P.; Batson, B.; Bhansali, S.; Greene, B.; Turner, R.

    2007-05-01

    In 2004, the University of South Florida (USF) was granted by the National Science Foundation a Louis Stokes Alliance for Minority Participation (LSAMP) Bridge to the Doctorate (BD) site award (HRD# 0217675). As part of the Florida-Georgia Louis Stokes Alliance for Minority Participation (FGLSAMP), USF is one of thirteen institutions in an alliance that is dedicated to significantly increasing the number of underrepresented minority students who obtain undergraduate and graduate STEM degrees. The BD program at USF incorporates the goals of FGLSAMP and facilitates the recruitment of underrepresented minorities pursuing careers in the STEM fields at the graduate level. The thematic focus of the FGLSAMP USF BD program is focused on the development and application of biogeochemical sensors for marine, aquatic, environmental, remote sensing and biomedical applications. After recruitment, BD graduate fellowship recipients are provided with NSF-funded financial support for two years, and opportunities to participate in professional development workshops, seminars and short courses, as well as additional financial support to pursue and complete their doctoral studies (beyond the initial two years of NSF BD funding), in a variety of forms, including, but not limited to, Alfred P. Sloan Minority Scholarships, Florida Education Fund's McKnight Doctoral Fellowships, USF College of Graduate Studies Fellowships, USF CMS endowed fellowships, USF CMS research assistantships, and USF CMS teaching assistantships. Collectively, 3 LSAMP BD grants have been awarded at USF to support 56 underrepresented minority fellowship recipients, of which 14 are currently graduate students at the USF College of Marine Science (CMS). Since the arrival of the BD Fellowship program, the graduate community has diversified, showing an increase of over 40% in underrepresented minorities at CMS. The BD program has enhanced the research and learning environment for all CMS students, as well as fostered a nurturing community of underrepresented minority CMS graduate students committed to obtaining their doctoral degrees. As of spring 2007, a total of 4 BD fellowship recipients have obtained marine science master's degrees and are currently pursuing their doctoral degrees in the CMS. In addition, in less than two years, a BD endowment fund of more than $900,000 was established. This fund will provide financial support for at least two minority CMS graduate students in perpetuity! Lastly, in response to an identified need for increased ocean literacy among underrepresented groups, several BD fellowship recipients have engaged in activities designed to "give back" via informal and formal education and outreach opportunities within their native communities.

  18. Analysis of tandem E-box motifs within human Complement receptor 2 (CR2/CD21) promoter reveals cell specific roles for RP58, E2A, USF and localized chromatin accessibility.

    PubMed

    Cruickshank, Mark N; Dods, James; Taylor, Rhonda L; Karimi, Mahdad; Fenwick, Emily J; Quail, Elizabeth A; Rea, Alexander J; Holers, V Michael; Abraham, Lawrence J; Ulgiati, Daniela

    2015-07-01

    Complement receptor 2 (CR2/CD21) plays an important role in the generation of normal B cell immune responses. As transcription appears to be the prime mechanism via which surface CR2/CD21 expression is controlled, understanding transcriptional regulation of this gene will have broader implications to B cell biology. Here we report opposing, cell-context specific control of CR2/CD21 promoter activity by tandem E-box elements, spaced 22 bp apart and within 70 bp of the transcription initiation site. We have identified E2A and USF transcription factors as binding to the distal and proximal E-box sites respectively in CR2-positive B-cells, at a site that is hypersensitive to restriction enzyme digestion compared to non-expressing K562 cells. However, additional unidentified proteins have also been found to bind these functionally important elements. By utilizing a proteomics approach we have identified a repressor protein, RP58, binding the distal E-box motif. Co-transfection experiments using RP58 overexpression constructs demonstrated a specific 10-fold repression of CR2/CD21 transcriptional activity mediated through the distal E-box repressor element. Taken together, our results indicate that repression of the CR2/CD21 promoter can occur through one of the E-box motifs via recruitment of RP58 and other factors to bring about a silenced chromatin context within CR2/CD21 non-expressing cells. Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. Development of "Remotely Operated Vehicles for Education and Research" (ROVERs)

    NASA Astrophysics Data System (ADS)

    Gaines, J. E.; Bland, G.; Bydlowski, D.

    2017-12-01

    The University of South Florida is a team member for the AREN project which develops educational technologies for data acquisition. "Remotely Operated Vehicles for Education and Research" (ROVERs) are floatable data acquisition systems used for Earth science measurements. The USF partnership was productive in the first year, resulting in new autonomous ROVER platforms being developed and used during a 5 week STEM summer camp by middle school youth. ROVERs were outfitted with GPS and temperature sensors and programmed to move forward, backwards, and to turn autonomously using the National Instruments myRIO embedded system. GLOBE protocols were used to collect data. The outreach program's structure lended itself to accomplishing an essential development effort for the AREN project towards the use of the ROVER platform in informal educational settings. A primary objective of the partnership is curriculum development to integrate GLOBE protocols and NASA technology and hardware/ROVER development wher new ROVER platforms are explored. The USF partnership resulted in two design prototypes for ROVERs, both of which can be created from recyclable materials for flotation and either 3D printed or laser cut components. In addition, both use the National Instruments myRIO for autonomous control. We will present two prototypes designed for use during the USF outreach program, the structure of the program, and details on the fabrication of prototype Z during the program by middle school students. Considering the 5-year objective of the AREN project is to "develop approaches, learning plans, and specific tools that can be affordably implemented nationwide (globally)", the USF partnership is key as it contributes to each part of the objective in a unique and impactful way.

  20. Ethanol and dietary unsaturated fat (corn oil/linoleic acid enriched) cause intestinal inflammation and impaired intestinal barrier defense in mice chronically fed alcohol.

    PubMed

    Kirpich, Irina A; Feng, Wenke; Wang, Yuhua; Liu, Yanlong; Beier, Juliane I; Arteel, Gavin E; Falkner, K Cameron; Barve, Shirish S; McClain, Craig J

    2013-05-01

    Alcohol and dietary fat both play an important role in alcohol-mediated multi-organ pathology, including gut and liver. In the present study we hypothesized that the combination of alcohol and dietary unsaturated fat (USF) would result in intestinal inflammatory stress and mucus layer alterations, thus contributing to disruption of intestinal barrier integrity. C57BL/6N mice were fed Lieber-DeCarli liquid diets containing EtOH and enriched in USF (corn oil/linoleic acid) or SF (medium chain triglycerides: beef tallow) for 8 weeks. Intestinal histology, morphometry, markers of inflammation, as well as levels of mucus protective factors were evaluated. Alcohol and dietary USF triggered an intestinal pro-inflammatory response, characterized by increase in Tnf-α, MCP1, and MPO activity. Further, alcohol and dietary USF, but not SF, resulted in alterations of the intestinal mucus layer, characterized by decreased expression of Muc2 in the ileum. A strong correlation was observed between down-regulation of the antimicrobial factor Cramp and increased Tnf-α mRNA. Therefore, dietary unsaturated fat (corn oil/LA enriched) is a significant contributing factor to EtOH-mediated intestinal inflammatory response and mucus layer alterations in rodents. Copyright © 2013 Elsevier Inc. All rights reserved.

  1. CDC2 Mediates Progestin Initiated Endometrial Stromal Cell Proliferation: A PR Signaling to Gene Expression Independently of Its Binding to Chromatin

    PubMed Central

    Vallejo, Griselda; Mestre-Citrinovitz, Ana C.; Ballaré, Cecilia; Beato, Miguel; Saragüeta, Patricia

    2014-01-01

    Although non-genomic steroid receptor pathways have been studied over the past decade, little is known about the direct gene expression changes that take place as a consequence of their activation. Progesterone controls proliferation of rat endometrial stromal cells during the peri-implantation phase of pregnancy. We showed that picomolar concentration of progestin R5020 mimics this control in UIII endometrial stromal cells via ERK1-2 and AKT activation mediated by interaction of Progesterone Receptor (PR) with Estrogen Receptor beta (ERb) and without transcriptional activity of endogenous PR and ER. Here we identify early downstream targets of cytoplasmic PR signaling and their possible role in endometrial stromal cell proliferation. Microarray analysis of global gene expression changes in UIII cells treated for 45 min with progestin identified 97 up- and 341 down-regulated genes. The most over-represented molecular functions were transcription factors and regulatory factors associated with cell proliferation and cell cycle, a large fraction of which were repressors down-regulated by hormone. Further analysis verified that progestins regulate Ccnd1, JunD, Usf1, Gfi1, Cyr61, and Cdkn1b through PR-mediated activation of ligand-free ER, ERK1-2 or AKT, in the absence of genomic PR binding. ChIP experiments show that progestin promoted the interaction of USF1 with the proximal promoter of the Cdc2 gene. Usf1 knockdown abolished Cdc2 progestin-dependent transcriptional regulation and cell proliferation, which also blocked Cdc2 knockdown. We conclude that progestin-induced proliferation of endometrial stromal cells is mediated by ERK1-2 and AKT dependent early regulation of USF1, which directly induces Cdc2. To our knowledge, this is the first description of early target genes of progestin-activated classical PR via crosstalk with protein kinases and independently of hormone receptor binding to the genomic targets. PMID:24859236

  2. Worldwide trends in Universal Service Funds and telemedicine.

    PubMed

    Nakajima, Isao

    2010-12-01

    A survey of recent worldwide trends in Universal Service Funds (USFs) and the assistance provided for their application indicates that industrialized countries and developing nations alike have offered or plan to offer tax-relief measures or reimbursement for communications costs incurred by telemedicine programs, thus finding a way to actively apply USFs in rural areas. There are three main systems used to calculate the amount of reimbursement from a USF. While many countries adopt a service-area net-loss estimation method, Japan uses a benchmark method and provides financial assistance only to unprofitable areas. The USA has proactively introduced telemedicine to rural areas and isolated islands in order to minimize rapidly rising healthcare costs and to improve the efficiency of healthcare services. In the USA, the USF is used to pay back communications costs incurred through telemedicine programs. For instance, the budget allocated from the USF for reimbursements for telemedicine in Alaska reached USD 30 Mil. in 2007. Developing countries in Africa and Asia are operating various forms of telemedicine on a trial basis, but a tax-relief measure or payback of communications costs, which are a large portion of the running costs, will need to be implemented to ensure sustainable and autonomous operation of telemedicine. In Japan, up until January 2007, the USF system assumed the use of an NTS (non-traffic sensitive cost) system to obtain funds from connection fees, and this system would receive funds from each telecommunications carrier (payer: the telecommunications carriers). The beneficiaries would be limited to two companies, namely NTT East and NTT West. However, the Japanese USF system was revised in February 2007, and a fee is now collected from each telephone number (payer: the user). The collected funds are used to cover losses in unprofitable areas (not limited to remote areas) among 7,000 business areas in Japan. In view of worldwide trends, the author believes that Japan should also start using the USF system to reimburse communications costs (including costs of telemedicine) in order to achieve sustainable and autonomous operation of public communication systems in rural areas.

  3. Identity Recognition Algorithm Using Improved Gabor Feature Selection of Gait Energy Image

    NASA Astrophysics Data System (ADS)

    Chao, LIANG; Ling-yao, JIA; Dong-cheng, SHI

    2017-01-01

    This paper describes an effective gait recognition approach based on Gabor features of gait energy image. In this paper, the kernel Fisher analysis combined with kernel matrix is proposed to select dominant features. The nearest neighbor classifier based on whitened cosine distance is used to discriminate different gait patterns. The approach proposed is tested on the CASIA and USF gait databases. The results show that our approach outperforms other state of gait recognition approaches in terms of recognition accuracy and robustness.

  4. PHOTOCOPY OF STANDARD USDA/USFS PLAN FOR 13' X 13' STEEL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PHOTOCOPY OF STANDARD USDA/USFS PLAN FOR 13' X 13' STEEL LOOKOUT HOUSE (CAB); ELEVATIONS, SECTIONS, MISC. DETAILS; DATED 1961 - North Mountain Lookout, Stanislaus National Forest, Groveland, Tuolumne County, CA

  5. Collaborative implementation for ecological restoration on US Public Lands: implications for legal context, accountability, and adaptive management.

    PubMed

    Butler, William H; Monroe, Ashley; McCaffrey, Sarah

    2015-03-01

    The Collaborative Forest Landscape Restoration Program (CFLRP), established in 2009, encourages collaborative landscape scale ecosystem restoration efforts on United States Forest Service (USFS) lands. Although the USFS employees have experience engaging in collaborative planning, CFLRP requires collaboration in implementation, a domain where little prior experience can be drawn on for guidance. The purpose of this research is to identify the ways in which CFLRP's collaborative participants and agency personnel conceptualize how stakeholders can contribute to implementation on landscape scale restoration projects, and to build theory on dynamics of collaborative implementation in environmental management. This research uses a grounded theory methodology to explore collaborative implementation from the perspectives and experiences of participants in landscapes selected as part of the CFLRP in 2010. Interviewees characterized collaborative implementation as encompassing three different types of activities: prioritization, enhancing treatments, and multiparty monitoring. The paper describes examples of activities in each of these categories and then identifies ways in which collaborative implementation in the context of CFLRP (1) is both hindered and enabled by overlapping legal mandates about agency collaboration, (2) creates opportunities for expanded accountability through informal and relational means, and, (3) creates feedback loops at multiple temporal and spatial scales through which monitoring information, prioritization, and implementation actions shape restoration work both within and across projects throughout the landscape creating more robust opportunities for adaptive management.

  6. Collaborative Implementation for Ecological Restoration on US Public Lands: Implications for Legal Context, Accountability, and Adaptive Management

    NASA Astrophysics Data System (ADS)

    Butler, William H.; Monroe, Ashley; McCaffrey, Sarah

    2015-03-01

    The Collaborative Forest Landscape Restoration Program (CFLRP), established in 2009, encourages collaborative landscape scale ecosystem restoration efforts on United States Forest Service (USFS) lands. Although the USFS employees have experience engaging in collaborative planning, CFLRP requires collaboration in implementation, a domain where little prior experience can be drawn on for guidance. The purpose of this research is to identify the ways in which CFLRP's collaborative participants and agency personnel conceptualize how stakeholders can contribute to implementation on landscape scale restoration projects, and to build theory on dynamics of collaborative implementation in environmental management. This research uses a grounded theory methodology to explore collaborative implementation from the perspectives and experiences of participants in landscapes selected as part of the CFLRP in 2010. Interviewees characterized collaborative implementation as encompassing three different types of activities: prioritization, enhancing treatments, and multiparty monitoring. The paper describes examples of activities in each of these categories and then identifies ways in which collaborative implementation in the context of CFLRP (1) is both hindered and enabled by overlapping legal mandates about agency collaboration, (2) creates opportunities for expanded accountability through informal and relational means, and, (3) creates feedback loops at multiple temporal and spatial scales through which monitoring information, prioritization, and implementation actions shape restoration work both within and across projects throughout the landscape creating more robust opportunities for adaptive management.

  7. University of South Florida- Phase Change Materials (PCM)

    ScienceCinema

    Goswami, Yogi; Stefanakos, Lee

    2018-05-30

    USF is developing low-cost, high-temperature phase-change materials (PCMs) for use in thermal energy storage systems. Heat storage materials are critical to the energy storage process. In solar thermal storage systems, heat can be stored in these materials during the day and released at night--when the sun is not out--to drive a turbine and produce electricity. In nuclear storage systems, heat can be stored in these materials at night and released to produce electricity during daytime peak-demand hours. Most PCMs do not conduct heat very well. Using an innovative, electroless encapsulation technique, USF is enhancing the heat transfer capability of its PCMs. The inner walls of the capsules will be lined with a corrosion-resistant, high-infrared emissivity coating, and the absorptivity of the PCM will be controlled with the addition of nano-sized particles. USF's PCMs remain stable at temperatures from 600 to 1,000°C and can be used for solar thermal power storage, nuclear thermal power storage, and other applications.

  8. Deep patch technique for landslide repair. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Helwany, B.M.

    1994-10-01

    The report describes the laboratory testing of the `USFS deep patch` technique and a CTI modification of this technique for repairing landslides with geosynthetic reinforcement. The technique involves replacing sections of roadway lost due to landslides on top of a geosynthetically-reinforced embankment. The CTI modification involves replacing the reinforced slope with a geosynthetically-reinforced retaining wall with a truncated base. Both techniques rely on the cantilevering ability of the reinforced mass to limit the load on the foundation with a high slide potential. The tests with road base showed that (1) both the USFS and CTI repair reduced effectively the adversemore » effects of local landsliding on the highway pavement by preventing crack propagation; (2) the USFS repair increased the stability of the repaired slope, which was in progressive failure, by reducing the stresses exerted on it; and (3) the CTI repair produced substantially greater stresses on its foundation due to the truncated base of the reinforced mass.« less

  9. People, Places, and Pandas: Engaging Preschoolers with Interactive Whiteboards

    ERIC Educational Resources Information Center

    Berson, Ilene R.; Cross, Megan D.; Ward, Jennifer; Berson, Michael J.

    2014-01-01

    In this article, the authors describe a recent project undertaken at the University of South Florida's (USF) Preschool for Creative Learning. To align with the inquiry approach of their laboratory school, the environment at the Preschool is designed so that children can learn through exploration and individual initiative. The administration and…

  10. Reciprocal Education Experiences In Two GK-12 Programs: Teachers Learning And Students Teaching In Diverse Settings

    NASA Astrophysics Data System (ADS)

    Mayo, M.; Williams, C.; Rodriguez, T.; Greely, T.; Pyrtle, A. J.; Rivera-Rentas, A. L.; Vilches, M.

    2004-12-01

    The National Science Foundation's Graduate Teaching Fellows in K-12 Education (GK-12) Program has enabled science, technology, engineering and mathematics (STEM) graduate schools across the country to become more active in local area K-12 schools. An overview of a graduate student's experiences, insights gained and lessons learned as a Fellow in the 2003-2004 Universidad Metropolitana's (UMET) environmental science and the 2004-2005 University of South Florida's (USF) ocean science GK-12 Programs is presented. The major goals of the 2003-2004 UMET GK-12 Program were 1) to enrich environmental science teaching and learning via a thematic approach in eight local public schools and 2) to provide UMET graduate students with exposure to teaching methodologies and practical teaching experience. Utilizing examples from local environments in and nearby Carolina, Puerto Rico to teach key science principles at Escuela de la Comunidad Juana Rodriguez Mundo provided numerous opportunities to relate science topics to students' daily life experiences. By 2004, the UMET GK-12 Program had successfully engaged the entire student body (primarily comprised of bilingual minority kindergarten to sixth graders), teachers and school administrators in environment-focused teaching and learning activities. Examples of such activities include tree planting projects to minimize local erosion, conducting a science fair for the first time in many years, and numerous opportunities to experience what "real scientists do" while conducting environmental science investigations. During the 2004-2005 academic year, skills, insights and lessons learned as a UMET GK-12 Fellow are being further enhanced through participation in the USF GK-12 OCEANS Program. The overall objectives of the 2004-2005 USF GK-12 OCEANS assignment at Madeira Beach Elementary School in Saint Petersburg, Florida are to 1) engage students from various ethnic backgrounds and cultures in hands-on science activities, 2) enhance the school's third grade ocean science education curriculum, and 3) foster dialog between students at Madeira Beach Elementary School and Escuela de la Comunidad Juana Rodriguez Mundo, via exchange of pictures, video recordings, letters and emails related to environment-focused learning activities being undertaken at the two schools. In addition to these objectives, during the 2004-2005 academic year several ocean science-focused activities, the majority of which were adapted and/or identified from either the UMET GK-12 or USF OCEAN GK-12 Programs, will be utilized to further stimulate Madeira Beach Elementary School third graders' critical thinking skills. Examples of such activities, including hands-on exercises, case studies, games and field trips are highlighted in this presentation.

  11. 77 FR 11109 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-24

    ...-Native Plant Control Project, Proposes a Forest-Wide Integrated Management Strategy to Control the Spread..., Final EIS, USFS, SD, Steamboat Project, Proposes to Implement Multiple Resource Management Actions... EIS, USFS, WA, South George Vegetation and Fuels Management Project, To Improve Forest Health and...

  12. 77 FR 13257 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-06

    ..., Office of Information and Regulatory Affairs, Office of Management and Budget (OMB), Washington, DC, OIRA... Resource Management Plan (USFS 1990) and Upper McKenzie River Management Plan (``UMRMP,'' USFS 1992), (2...) inform management practices to protect and enhance the outstandingly remarkable values identified for the...

  13. Fire management assessment of Eastern Province, Zambia

    Treesearch

    L. T. Hollingsworth; D. Johnson; G. Sikaundi; S. Siame

    2015-01-01

    The mission that produced this assessment was prompted by requests from Forestry Department personnel in Zambia to the United States Agency for International Development (USAID) for formal fire management training. USAID contacted the United States Forest Service's (USFS) International Programs (IP) with the training request. Together, USFS, USAID, and Zambian...

  14. Combating the stress of residency: one school's approach.

    PubMed

    Dabrow, Sharon; Russell, Stephen; Ackley, Karen; Anderson, Eric; Fabri, Peter Jeff

    2006-05-01

    Residency is a time of stress and turmoil for many residents. The stresses are varied and great, often involving both personal and professional issues. One institutional mechanism that has been shown to help residents cope with stress is the use of residents' wellness, or assistance, programs. The University of South Florida (USF) College of Medicine developed the USF Residency Assistance Program (RAP) in 1997, modeled after business employee assistance programs but tailored to enhance the well-being of residents. The program was developed in an organized, thoughtful manner starting with a Request for Proposals to all local employee assistance programs and the selection of one of these to run the program. The RAP is broad-based, readily available, easily accessible, totally voluntary and confidential, and not reportable to the state board of medicine. It is well integrated into all residency programs and has had excellent acceptance from the administration; information about access to the RAP is available to all residents through multiple venues. The cost is minimal, at only seven cents a day per resident. The authors present data from the eight years the RAP has been operating, including information on program use, referral rates, acceptance, and types of problems encountered. One suicide occurred during this time period, and the RAP provided a significant role in grief counseling. Assistance programs are critical to the well-being of residents. The USF program presents a model that can be used by other programs around the country.

  15. 78 FR 76789 - Additional Connect America Fund Phase II Issues

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-19

    ... inspection and copying during normal business hours in the FCC Reference Information Center, Portals II, 445... Phase I to Phase II. 2. Timing of Phase II Support Disbursements. In the USF/ICC Transformation Order... language in paragraph 180 of the USF/ICC Transformation Order. We now seek to more fully develop the record...

  16. Florida Public Health Training Center: Evidence-Based Online Mentor Program

    ERIC Educational Resources Information Center

    Frahm, Kathryn A.; Alsac-Seitz, Biray; Mescia, Nadine; Brown, Lisa M.; Hyer, Kathy; Liburd, Desiree; Rogoff, David P.; Troutman, Adewale

    2013-01-01

    This article describes an Online Mentor Program (OMP) designed to support and facilitate mentorships among and between Florida Department of Health (FDOH) employees and USF College of Public Health students using a Web-based portal. The Florida Public Health Training Center (FPHTC) at the University of South Florida (USF) College of Public Health…

  17. A Study of Instructional Faculty Salaries at USF, SUS and National Peers

    ERIC Educational Resources Information Center

    Micceri, Theodore

    2010-01-01

    This study investigates 10-year trends in instructional faculty salaries by sex and rank for USF, five SUS Peers (UF, FSU, FIU, UCF, FAU) and eight National Peers (North Carolina State, Alabama-Birmingham, Illinois-Chicago, California-Irvine, SUNY-Stony Brook, SUNY-Buffalo, Cincinnati, Rutgers). Methods: Historical instructional faculty salary…

  18. View west from USFS Road 369 toward Fowler Lode Adit ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View west from USFS Road 369 toward Fowler Lode Adit and O'Brien Ditch (left) and open-pit excavation (top-center, beyond trees); ridge saddle is in center - Steamboat Mine, Southeast slope of Steamboat Mountain, west of the junction of Forest Service Roads 1000300 and 1000365, Jacksonville, Jackson County, OR

  19. USDA Forest Service goals and programs for monitoring neotropical migratory birds

    Treesearch

    Patricia Manley

    1993-01-01

    The USDA Forest Service (USFS) developed goals, objectives, and guidelines for monitoring neotropical migratory birds (NTMB) on National Forest System lands in response to the Neotropical Migratory Bird Conservation Program Partners in Flight. A USFS task group developed a hierarchical monitoring framework designed to define priorities for type of monitoring data....

  20. Money and Mentorship

    ERIC Educational Resources Information Center

    Lim, Victoria

    2008-01-01

    This article describes how the benefactors of University of South Florida (USF) Latino Scholarship Program (LSP) support students in more ways than one. LSP, now in its 17th year, was started by the Latin Community Advisory Committee to the USF president to attract Hispanic students to the school. The committee didn't want to just provide…

  1. 75 FR 68355 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-05

    ... District Olympic National Forest, Olympic National Park, Jefferson County, WA, Wait Period Ends: 12/06/2010...: Lynne Urquhart 334-274-6371. EIS No. 20100431, Final EIS, USFS, WA, Dosewallips Road Washout Project, To...: 12/20/2010, Contact: Amy Henry 865-632-4045. EIS No. 20100433, Final EIS, USFS, CA, Plumas National...

  2. National FIA plot intensification procedure report

    Treesearch

    Jock A. Blackard; Paul L. Patterson

    2014-01-01

    The Forest Inventory and Analysis (FIA) program of the U.S. Forest Service (USFS) measures a spatially distributed base grid of forest inventory plots across the United States. The sampling intensity of plots may be increased in some regions when warranted by specific inventory objectives. Several intensification methods have been developed within FIA and USFS National...

  3. The Applegate Adaptive Management Area ecosystem health assessment

    Treesearch

    Thomas Atzet

    1995-01-01

    As requested by the Applegate Partnership, the Medford District Bureau of Land Management, the Rogue River and Siskiyou National Forests, a team of six specialists (Dr. Tom Atzet, USFS ecologist; Dr. Mike Amaranthus, PNW soil scientist, Dr. Don Goheen, USFS pathologist and entomologist, Tom Sensenig, BLM silviculturist, Dr. Dave Perry, Oregon State University...

  4. Learning from wilderness: The social dimension of fire management

    Treesearch

    Anne E. Black

    2009-01-01

    In 2008, the U.S. Forest Service (USFS) began piloting a "new" concept in fire management: managing "fire as fire" on the landscape; no more black-and-white distinctions between "good" fire and "bad" fire. Instead, under the new direction, the USFS manages the fire based on what the land, the long-term objectives, the land...

  5. 78 FR 34016 - Wireline Competition Bureau Seeks Comment on Options To Promote Rural Broadband in Rate-Of-Return...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-06

    ... document is available for inspection and copying during normal business hours in the FCC Reference... carriers supports such networks, and indeed, under the USF/ICC Transformation Order, 76 FR 73830, November... originally sought comment on this proposal in the USF/ICC Transformation Order FNPRM, 76 FR 73830, November...

  6. Geropsychology Post-Doctoral Training in Public Sector Service Delivery: The USF/Tampa VA Fellowship Model

    ERIC Educational Resources Information Center

    Molinari, Victor; Chiriboga, David A.; Schonfeld, Lawrence; Haley, William E.; Schinka, John A.; Hyer, Kathy; Dupree, Larry W.

    2005-01-01

    There is a growing need for geropsychologists who are specialists in practice, research, education, and advocacy for older adults. The combined USF/Tampa VA geropsychology fellowship program focuses on the training of three post-doctoral Fellows each year in public sector service delivery across diverse long term care (LTC) and primary care…

  7. Urban forest health monitoring: large-scale assessments in the United States

    Treesearch

    Anne Buckelew Cumming; Daniel B. Twardus; David J. Nowak

    2008-01-01

    The U.S. Department of Agriculture, Forest Service (USFS), together with state partners, developed methods to monitor urban forest structure, function, and health at a large statewide scale. Pilot studies have been established in five states using protocols based on USFS Forest Inventory and Analysis and Forest Health Monitoring program data collection standards....

  8. Evaluation of open source data mining software packages

    Treesearch

    Bonnie Ruefenacht; Greg Liknes; Andrew J. Lister; Haans Fisk; Dan Wendt

    2009-01-01

    Since 2001, the USDA Forest Service (USFS) has used classification and regression-tree technology to map USFS Forest Inventory and Analysis (FIA) biomass, forest type, forest type groups, and National Forest vegetation. This prior work used Cubist/See5 software for the analyses. The objective of this project, sponsored by the Remote Sensing Steering Committee (RSSC),...

  9. Land cover change map comparisons using open source web mapping technologies

    Treesearch

    Erik Lindblom; Ian Housman; Tony Guay; Mark Finco; Kevin Megown

    2015-01-01

    The USDA Forest Service is evaluating the status of current landscape change maps and assessing gaps in their information content. These activities have been occurring under the auspices of the Landscape Change Monitoring System (LCMS) project, which is a joint effort between USFS Research, USFS Remote Sensing Applications Center (RSAC), USGS Earth Resources...

  10. What are the best seed sources for ecosystem restoration on BLM and USFS lands?

    Treesearch

    Larry Stritch; Peggy Olwell; Scott Lambert; Matthew E. Horning; Richard Cronn

    2010-01-01

    Native plant restoration policy calls for use of "genetically appropriate" native plant material on USDI Bureau of Land Management (BLM) and USDA Forest Service (USFS) lands. In this article, we summarize experimental evidence showing that local adaptation is widespread in all kingdoms of life, and how this "home-field advantage" has been exploited...

  11. Using FIA and landsat observations to improve the spatial and temporal resolution of forest carbon estimates

    Treesearch

    Karen Schleeweis; Chengquan Huang; Khaldoun Rishmawi; Feng Aron Zhao; Jeffery G. Masek; Richard K. Houghton; Samuel N. Goward

    2015-01-01

    For nearly a decade, the USFS FIA, NASA, and the University of Maryland have collaborated on the NASA/NACP funded North American Forest Dynamics (NAFD) project, and developed new approaches for annual mapping of CONUS forest dynamics (1984-2011). Building on this foundation of empirical research and results, the collaboration will continue with a new Carbon Cycle...

  12. "It was a young man's life": G. A. Pearson

    Treesearch

    Susan D. Olberding

    2008-01-01

    The nation's initial USFS research site commenced in a rustic cabin in the midst of northern Arizona's expansive ponderosa pine forest. Gustaf A. Pearson was the first in a distinguished line of USFS scientists to live and study there. A visitor to Fort Valley today often wishes he could have stood in Pearson's large boots (he was said to have enormous...

  13. The North Cascadia Adaptation Partnership: a science-management collaboration for responding to climate change

    Treesearch

    Crystal L. Raymond; David L. Peterson; Regina M. Rochefort

    2013-01-01

    The U.S. Forest Service (USFS) and National Park Service (NPS) have highlighted climate change as an agency priority and issued direction to administrative units for responding to climate change. In response, the USFS and NPS initiated the North Cascadia Adaptation Partnership (NCAP) in 2010. The goals of the NCAP were to build an inclusive partnership, increase...

  14. Riparian area protection and outdoor recreation: lessons from the Northwest Forest Plan

    Treesearch

    Patrick Impero Wilson; Troy E. Hall; Linda E. Kruger

    2012-01-01

    The Northwest Forest Plan required the US Forest Service (USFS) to shift its management focus to ecological values rather than the utilitarian ones that had dominated forest policy in the region. This article examines the effects of this shift on the USFS's historic mission to provide recreational access to the region's forests. Focusing on six national...

  15. Conterminous U.S. and Alaska Forest Type Mapping Using Forest Inventory and Analysis Data

    Treesearch

    B. Ruefenacht; M.V. Finco; M.D. Nelson; R. Czaplewski; E.H. Helmer; J. A. Blackard; G.R. Holden; A.J. Lister; D. Salajanu; D. Weyermann; K. Winterberger

    2008-01-01

    Classification-trees were used to model forest type groups and forest types for the conterminous United States and Alaska. The predictor data were a geospatial data set with a spatial resolution of 250 m developed by the U.S. Department of Agriculture Forest Service (USFS). The response data were plot data from the USFS Forest Inventory and Analysis program. Overall...

  16. 75 FR 30757 - Endangered and Threatened Wildlife and Plants; 12-Month Finding on a Petition to Delist Cirsium...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-02

    .... 8-9). The extent of C. vinaceum habitat on private property inholdings (privately owned land within... identified, of which 58 were on USFS land (Service 1993, p. 2). In 1995, there were 77 sites known to occur... species in 1987, surveys of USFS land estimated Cirsium vinaceum to be a species with 10,000 to 15,000...

  17. Management perceptions of off-highway vehicle use on national forest system lands in Appalachia

    Treesearch

    Katherine A. Thompson; Chad D. Pierskalla; Michael A. Schuett

    2008-01-01

    In 2005, the U.S. Forest Service (USFS) issued new standards for dealing with unmanaged recreation. All National Forest System units are to develop travel management plans by 2009. The purpose of this study was to determine differences in perceptions between USFS managers of national forests in Appalachia with low and high levels of offhighway vehicle (OHV) use...

  18. "It was a young man's life": G.A. Pearson (P-53)

    Treesearch

    Susan D. Olberding

    2008-01-01

    The nation's initial USFS research site commenced in a rustic cabin in the midst of northern Arizona’s expansive ponderosa pine forest. Gustaf A. Pearson was the first in a distinguished line of USFS scientists to live and study there. A visitor to Fort Valley today often wishes he could have stood in Pearson's large boots (he was said to have enormous feet)...

  19. Northern Region Landbird Monitoring Program: A USFS-University of Montana Partnership Designed to Provide Both Short-term and Long-term Feedback for Land Managers

    Treesearch

    R. Hutto; Skip Kowalski

    2006-01-01

    The Northern Region Landbird Monitoring Program (NRLMP) began in 1990 as a cooperative effort between the United States Forest Service (USFS) and the University of Montana. The combination of a research-oriented perspective from the University and a management-needs perspective from the National Forests within the Northern Region led to the realization that landbirds...

  20. AMPK activation represses the human gene promoter of the cardiac isoform of acetyl-CoA carboxylase: Role of nuclear respiratory factor-1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Adam, Tasneem; Opie, Lionel H.; Essop, M. Faadiel, E-mail: mfessop@sun.ac.za

    Research highlights: {yields} AMPK inhibits acetyl-CoA carboxylase beta gene promoter activity. {yields} Nuclear respiratory factor-1 inhibits acetyl-CoA carboxylase beta promoter activity. {yields} AMPK regulates acetyl-CoA carboxylase beta at transcriptional level. -- Abstract: The cardiac-enriched isoform of acetyl-CoA carboxylase (ACC{beta}) produces malonyl-CoA, a potent inhibitor of carnitine palmitoyltransferase-1. AMPK inhibits ACC{beta} activity, lowering malonyl-CoA levels and promoting mitochondrial fatty acid {beta}-oxidation. Previously, AMPK increased promoter binding of nuclear respiratory factor-1 (NRF-1), a pivotal transcriptional modulator controlling gene expression of mitochondrial proteins. We therefore hypothesized that NRF-1 inhibits myocardial ACC{beta} promoter activity via AMPK activation. A human ACC{beta} promoter-luciferase construct was transientlymore » transfected into neonatal cardiomyocytes {+-} a NRF-1 expression construct. NRF-1 overexpression decreased ACC{beta} gene promoter activity by 71 {+-} 4.6% (p < 0.001 vs. control). Transfections with 5'-end serial promoter deletions revealed that NRF-1-mediated repression of ACC{beta} was abolished with a pPII{beta}-18/+65-Luc deletion construct. AMPK activation dose-dependently reduced ACC{beta} promoter activity, while NRF-1 addition did not further decrease it. We also investigated NRF-1 inhibition in the presence of upstream stimulatory factor 1 (USF1), a known transactivator of the human ACC{beta} gene promoter. Here NRF-1 blunted USF1-dependent induction of ACC{beta} promoter activity by 58 {+-} 7.5% (p < 0.001 vs. control), reversed with a dominant negative NRF-1 construct. NRF-1 also suppressed endogenous USF1 transcriptional activity by 55 {+-} 6.2% (p < 0.001 vs. control). This study demonstrates that NRF-1 is a novel transcriptional inhibitor of the human ACC{beta} gene promoter in the mammalian heart. Our data extends AMPK regulation of ACC{beta} to the transcriptional level.« less

  1. High-Volume Airborne Fluids Handling Technologies to Fight Wildfires

    NASA Technical Reports Server (NTRS)

    Dickerson, Mark; Cox, Timothy; Hale, Cliff; Hatton, Rick

    2010-01-01

    NASA recently partnered with the U.S. Forest Service (USFS) on a project to examine mission suitability and recommend policies and procedures for the use of very large aerial firefighting aircraft such as the Boeing 747 and DC-10 aerial retardant delivery aircraft. The aircraft under study included a 10Tanker DC-10 and an Evergreen B-747. NASA's Dryden Flight Research Center and Ames Research Center worked with the USFS to help determine the safe flight envelope for these Very Large Air Tanker (VLAT) aircraft for the USFS and the Department of the Interior (DOI). This new generation of supertankers includes aircraft like these that have as much as four times the delivery capacity of the previous generation of aerial firefighting aircraft. Dryden performed operational test and evaluation assessments and reported findings and recommendations on these aircraft in cooperation with Ames. The team developed, implemented, and directed an evaluation test plan for use in flight test and in simulation. Ames provided support using pilot-in-the-loop simulations and coordinated simulator models, flight profiles, and data analysis with Dryden. The test plan was designed to evaluate the suitability of VLAT aircraft as a function of mission environment. Based on this analysis, NASA generated interim flight envelope limitations to enhance safety and operational utility in the fire-retardant delivery mission. These recommended flight limitations were adopted by the USFS. The 10Tanker DC-10 has been in use for several years with the California Department of Forestry and Fire Protection(Cal-Fire), but until NASA took on the challenge of reviewing VLAT capabilities and limitations, the USFS was hesitant to add them to the federal wildfire arsenal. The DC-10 delivery system is based on an externally mounted set of tanks and a bomb-bay style set of clamshell doors that are opened in precisely calibrated ways to deliver the amounts and concentrations of retardant called for by the specific wildfire situation. The system was manufactured by Jordan Air of Central Point, OR, and was installed by Victorville Aerospace in Victorville, CA. It can deliver 12,000 gallons (45.4 kL) of retardant in as little as eight seconds. The aircraft can deliver a partial load of retardant and make multiple drops on the same flight, or the entire load can be rapidly delivered in one pass if required for maximum coverage. The Evergreen 747 uses internal tankage and a pressurized delivery system to enable volume and coverage levels that also meet USFS requirements, but enables computer control of flow for desired precision. This system was designed and built by Adaptive Aerospace of Tehachapi, CA and can deliver about 20,000 gallons (75.7 kL) of retardant in approximately ten seconds. The 747 can also make multiple independent drops, or deliver the entire load at once. NASA found that both of these VLAT aircraft are compatible with the wildfire suppression mission when used to supplement other aerial retardant delivery platforms. The major recommendations for deployment that resulted from this study relate to terrain clearance, the type of terrain in the drop area, availability of qualified lead planes to guide the VLAT approach to the drop area, and low-altitude maneuvering limitations. NASA s analysis suggests that with the appropriate flight procedures, these aircraft will provide a powerful set of tools to fight wildfires.

  2. Learning to Live with Off-Highway Vehicles: Lessons Learned from the Dixie National Forest

    Treesearch

    Aaron K. Divine; Pamela E. Foti

    2004-01-01

    Nationwide, there are an estimated 446,000 miles of road on United States Forest Service (USFS) lands—four times that of any other public land management agency (USDA 2000; Havlick 2002). Most USFS roads were developed as part of a network to access timber on some 192 million acres of forested land during the past century (Forman et al. 2003). In recent years,...

  3. Southern California Disasters II

    NASA Technical Reports Server (NTRS)

    Nicholson, Heather; Todoroff, Amber L.; LeBoeuf, Madeline A.

    2015-01-01

    The USDA Forest Service (USFS) has multiple programs in place which primarily utilize Landsat imagery to produce burn severity indices for aiding wildfire damage assessment and mitigation. These indices provide widely-used wildfire damage assessment tools to decision makers. When the Hyperspectral Infrared Imager (HyspIRI) is launched in 2022, the sensor's hyperspectral resolution will support new methods for assessing natural disaster impacts on ecosystems, including wildfire damage to forests. This project used simulated HyspIRI data to study three southern California fires: Aspen, French, and King. Burn severity indices were calculated from the data and the results were quantitatively compared to the comparable USFS products currently in use. The final results from this project illustrate how HyspIRI data may be used in the future to enhance assessment of fire-damaged areas and provide additional monitoring tools for decision support to the USFS and other land management agencies.

  4. Temperature-dependent stability of stacking faults in Al, Cu and Ni: first-principles analysis.

    PubMed

    Bhogra, Meha; Ramamurty, U; Waghmare, Umesh V

    2014-09-24

    We present comparative analysis of microscopic mechanisms relevant to plastic deformation of the face-centered cubic (FCC) metals Al, Cu, and Ni, through determination of the temperature-dependent free energies of intrinsic and unstable stacking faults along [1 1̄ 0] and [1 2̄ 1] on the (1 1 1) plane using first-principles density-functional-theory-based calculations. We show that vibrational contribution results in significant decrease in the free energy of barriers and intrinsic stacking faults (ISFs) of Al, Cu, and Ni with temperature, confirming an important role of thermal fluctuations in the stability of stacking faults (SFs) and deformation at elevated temperatures. In contrast to Al and Ni, the vibrational spectrum of the unstable stacking fault (USF[1 2̄ 1]) in Cu reveals structural instabilities, indicating that the energy barrier (γusf) along the (1 1 1)[1 2̄ 1] slip system in Cu, determined by typical first-principles calculations, is an overestimate, and its commonly used interpretation as the energy release rate needed for dislocation nucleation, as proposed by Rice (1992 J. Mech. Phys. Solids 40 239), should be taken with caution.

  5. Regional Model Studies Nested in HYCOM. Application to the West Florida Shelf and the Cariaco Basin using ROMS

    DTIC Science & Technology

    2007-09-30

    marine.usf.edu Aida Alvera -Azcárate Phone: (727) 553-3508 Fax: (727) 553 1189 email: aalvera@marine.usf.edu Alexander Barth, Phone: (727...WFS and the data assimilation are being performed by Alexander Barth. The Cariaco nesting is performed by Aida Alvera -Azcárate. WORK COMPLETED...363–380. Barth, A., Beckers, J.-M., Alvera -Azcárate, A. and Weisberg, R.H. (2007), Filtering inertia-gravity waves from the initial conditions of

  6. Flotation Analysis for Boat Docks on U.S. Army Corps of Engineers Projects. Recreation Management Support Program

    DTIC Science & Technology

    2009-06-01

    USACE 2008c)) on June 3, 1992 that “effectively precludes the future use of expanded polystyrene unless it is encased in an approved protective coating...punctured. Closed cell (extruded) expanded polystyrene of good quality and manufac- tured for marine use will be required. Lesser quality foam bead flota...Forest Service (USFS) (USFS 2008) – “Open cell Expanded Polystyrene Foam (EPS) has an open structure that easily lets water into its interior. It

  7. Statistical studies of animal response data from USF toxicity screening test method

    NASA Technical Reports Server (NTRS)

    Hilado, C. J.; Machado, A. M.

    1978-01-01

    Statistical examination of animal response data obtained using Procedure B of the USF toxicity screening test method indicates that the data deviate only slightly from a normal or Gaussian distribution. This slight departure from normality is not expected to invalidate conclusions based on theoretical statistics. Comparison of times to staggering, convulsions, collapse, and death as endpoints shows that time to death appears to be the most reliable endpoint because it offers the lowest probability of missed observations and premature judgements.

  8. Yersinia enterocolitica YopT and Clostridium difficile Toxin B Induce Expression of GILZ in Epithelial Cells

    PubMed Central

    Köberle, Martin; Göppel, David; Grandl, Tanja; Gaentzsch, Peer; Manncke, Birgit; Berchtold, Susanne; Müller, Steffen; Lüscher, Bernhard; Asselin-Labat, Marie-Liesse; Pallardy, Marc; Sorg, Isabel; Langer, Simon; Barth, Holger; Zumbihl, Robert; Autenrieth, Ingo B.; Bohn, Erwin

    2012-01-01

    Glucocorticoid induced-leucine zipper (GILZ) has been shown to be induced in cells by different stimuli such as glucocorticoids, IL-10 or deprivation of IL-2. GILZ has anti-inflammatory properties and may be involved in signalling modulating apoptosis. Herein we demonstrate that wildtype Yersinia enterocolitica which carry the pYV plasmid upregulated GILZ mRNA levels and protein expression in epithelial cells. Infection of HeLa cells with different Yersinia mutant strains revealed that the protease activity of YopT, which cleaves the membrane-bound form of Rho GTPases was sufficient to induce GILZ expression. Similarly, Clostridium difficile toxin B, another bacterial inhibitor of Rho GTPases induced GILZ expression. YopT and toxin B both increased transcriptional activity of the GILZ promoter in HeLa cells. GILZ expression could not be linked to the inactivation of an individual Rho GTPase by these toxins. However, forced expression of RhoA and RhoB decreased basal GILZ promoter activity. Furthermore, MAPK activation proved necessary for profound GILZ induction by toxin B. Promoter studies and gel shift analyses defined binding of upstream stimulatory factor (USF) 1 and 2 to a canonical c-Myc binding site (E-box) in the GILZ promoter as a crucial step of its trans-activation. In addition we could show that USF-1 and USF-2 are essential for basal as well as toxin B induced GILZ expression. These findings define a novel way of GILZ promoter trans-activation mediated by bacterial toxins and differentiate it from those mediated by dexamethasone or deprivation of IL-2. PMID:22792400

  9. Biogeographic, cultural, and historical setting [Chapter 2

    Treesearch

    Hanna K. Olson; Don W. Fallon

    2018-01-01

    The Intermountain Adaptation Partnership (IAP) encompasses unique landscapes within the Intermountain Region of the U.S. Forest Service (USFS), from rugged mountains to deep canyons, from alpine snowfields to wild and scenic rivers (fig. 1.1). The area defined by the boundaries of the Intermountain Region contains both private and Federally owned lands, including 12...

  10. Advancing Fire Weather Research via Interagency Collaboration: The NOAA/USFS MOU

    NASA Astrophysics Data System (ADS)

    Schranz, S.; Pouyat, R.

    2012-12-01

    In 2005, the Western Governors' Association (WGA) first articulated the need for closer collaboration between NOAA and the land management agencies to improve our services - and to ensure the best new technology and scientific advances are infused into fire weather information and services. NOAA has taken the WGA advice very seriously and, over the past few years, have followed up by polling users of our fire weather information. This was done both by our Office of the Federal Coordinator for Meteorology, and via an examination of internal and collaborative research activities as conducted by NOAA's Science Advisory Board. Through these processes, and given the tight budget environment, it's become clear we can't make needed progress alone. We need to call upon our joint expertise, along with the expertise of partners across the federal, state, academic, and research communities. This talk will outline the NOAA/USFS MOU signed in August, 2012 and the collaborative research already begun with the USFS and other partners.

  11. High-Resolution Ultrasound-Switchable Fluorescence Imaging in Centimeter-Deep Tissue Phantoms with High Signal-To-Noise Ratio and High Sensitivity via Novel Contrast Agents

    PubMed Central

    Cheng, Bingbing; Bandi, Venugopal; Wei, Ming-Yuan; Pei, Yanbo; D’Souza, Francis; Nguyen, Kytai T.; Hong, Yi; Yuan, Baohong

    2016-01-01

    For many years, investigators have sought after high-resolution fluorescence imaging in centimeter-deep tissue because many interesting in vivo phenomena—such as the presence of immune system cells, tumor angiogenesis, and metastasis—may be located deep in tissue. Previously, we developed a new imaging technique to achieve high spatial resolution in sub-centimeter deep tissue phantoms named continuous-wave ultrasound-switchable fluorescence (CW-USF). The principle is to use a focused ultrasound wave to externally and locally switch on and off the fluorophore emission from a small volume (close to ultrasound focal volume). By making improvements in three aspects of this technique: excellent near-infrared USF contrast agents, a sensitive frequency-domain USF imaging system, and an effective signal processing algorithm, for the first time this study has achieved high spatial resolution (~ 900 μm) in 3-centimeter-deep tissue phantoms with high signal-to-noise ratio (SNR) and high sensitivity (3.4 picomoles of fluorophore in a volume of 68 nanoliters can be detected). We have achieved these results in both tissue-mimic phantoms and porcine muscle tissues. We have also demonstrated multi-color USF to image and distinguish two fluorophores with different wavelengths, which might be very useful for simultaneously imaging of multiple targets and observing their interactions in the future. This work has opened the door for future studies of high-resolution centimeter-deep tissue fluorescence imaging. PMID:27829050

  12. High-Resolution Ultrasound-Switchable Fluorescence Imaging in Centimeter-Deep Tissue Phantoms with High Signal-To-Noise Ratio and High Sensitivity via Novel Contrast Agents.

    PubMed

    Cheng, Bingbing; Bandi, Venugopal; Wei, Ming-Yuan; Pei, Yanbo; D'Souza, Francis; Nguyen, Kytai T; Hong, Yi; Yuan, Baohong

    2016-01-01

    For many years, investigators have sought after high-resolution fluorescence imaging in centimeter-deep tissue because many interesting in vivo phenomena-such as the presence of immune system cells, tumor angiogenesis, and metastasis-may be located deep in tissue. Previously, we developed a new imaging technique to achieve high spatial resolution in sub-centimeter deep tissue phantoms named continuous-wave ultrasound-switchable fluorescence (CW-USF). The principle is to use a focused ultrasound wave to externally and locally switch on and off the fluorophore emission from a small volume (close to ultrasound focal volume). By making improvements in three aspects of this technique: excellent near-infrared USF contrast agents, a sensitive frequency-domain USF imaging system, and an effective signal processing algorithm, for the first time this study has achieved high spatial resolution (~ 900 μm) in 3-centimeter-deep tissue phantoms with high signal-to-noise ratio (SNR) and high sensitivity (3.4 picomoles of fluorophore in a volume of 68 nanoliters can be detected). We have achieved these results in both tissue-mimic phantoms and porcine muscle tissues. We have also demonstrated multi-color USF to image and distinguish two fluorophores with different wavelengths, which might be very useful for simultaneously imaging of multiple targets and observing their interactions in the future. This work has opened the door for future studies of high-resolution centimeter-deep tissue fluorescence imaging.

  13. USGS Field Activities 11CEV01 and 11CEV02 on the West Florida Shelf, Gulf of Mexico, in January and February 2011

    USGS Publications Warehouse

    Robbins, Lisa L.; Knorr, Paul O.; Daly, Kendra L.; Taylor, Carl A.

    2014-01-01

    During January and February 2011 the U.S. Geological Survey (USGS), in cooperation with the University of South Florida (USF), conducted geochemical surveys on the west Florida Shelf. Data collected will allow USGS and USF scientists to investigate the effects of climate change on ocean acidification within the northern Gulf of Mexico, specifically, the effect of ocean acidification on marine organisms and habitats. This work is part of a larger USGS study on Climate and Environmental Variability (CEV). The first cruise was conducted from January 3 – 7 (11CEV01) and the second from February 17 - 27 (11CEV02). To view each cruise's survey lines, please see the Trackline page. Both cruises took place aboard the R/V Weatherbird II, a ship of opportunity led by Dr. Kendra Daly (USF), which departed and returned from Saint Petersburg, Florida. Data collection included sampling of the surface and water column (referred to as station samples) with lab analysis of pH, dissolved inorganic carbon (DIC), and total alkalinity. Augmenting the lab analysis was a continuous flow-through system with a Conductivity-Temperature-Depth (CTD) sensor, which also recorded salinity, and pH. Corroborating the USGS data are the vertical CTD profiles collected by USF. The CTD casts measured continuous vertical profiles of oxygen, chlorophyll fluorescence, optical backscatter, and transmissometer. Discrete samples for nutrients, chlorophyll, and particulate organic carbon/nitrogen were also collected during the CTD casts.

  14. Influence of dietary fat type on benzo(a)pyrene [B(a)P] biotransformation in a B(a)P-induced mouse model of colon cancer

    PubMed Central

    Diggs, Deacqunita L.; Myers, Jeremy N.; Banks, Leah D.; Niaz, Mohammad S.; Hood, Darryl B.; Roberts, L. Jackson; Ramesh, Aramandla

    2013-01-01

    In the US alone, around 60,000 lives/year are lost due to colon cancer. Diet and environment have been implicated in the development of sporadic colon tumors. The objective of this study was to determine how dietary fat potentiates the development of colon tumors through altered B(a)P biotransformation, using the Adenomatous polyposis coli with Multiple intestinal neoplasia mouse model. Benzo(a)pyrene was administered to mice through tricaprylin, and unsaturated (USF; peanut oil) and saturated (SF; coconut oil) fats at doses of 50 and 100 μg/kg via oral gavage over a 60-day period. Blood, colon, and liver were collected at the end of exposure period. The expression of B(a)P biotransformation enzymes [cytochrome P450 (CYP)1A1, CYP1B1 and glutathione-S-transferase] in liver and colon were assayed at the level of protein, mRNA and activities. Plasma and tissue samples were analyzed by reverse phase high-performance liquid chromatography for B(a)P metabolites. Additionally, DNA isolated from colon and liver tissues was analyzed for B(a)P-induced DNA adducts by the 32P-postlabeling method using a thin-layer chromatography system. Benzo(a)pyrene exposure through dietary fat altered its metabolic fate in a dose-dependent manner, with 100 μg/kg dose group registering an elevated expression of B(a)P biotransformation enzymes, and greater concentration of B(a)P metabolites, compared to the 50 μg/kg dose group (P<.05). This effect was more pronounced for SF group compared to USF group (P<.05). These findings establish that SF causes sustained induction of B(a)P biotransformation enzymes and extensive metabolism of this toxicant. As a consequence, B(a)P metabolites were generated to a greater extent in colon and liver, whose concentrations also registered a dose-dependent increase. These metabolites were found to bind with DNA and form B(a)P-DNA adducts, which may have contributed to colon tumors in a subchronic exposure regimen. PMID:24231098

  15. The effect of changes in the USF/NASA toxicity screening test method on data from some cellular polymers

    NASA Technical Reports Server (NTRS)

    Hilado, C. J.; Miller, C. M.

    1976-01-01

    Rankings of relative toxicity can be markedly affected by changes in test variables. Revision of the USF/NASA toxicity screening test procedure to eliminate the connecting tube and supporting floor and incorporate a 1.0 g sample weight, 200 C starting temperature, and 800 C upper limit temperature for pyrolysis, reversed the rankings of flexible polyurethane and polychloroprene foams, not only in relation to each other, but also in relation to cotton and red oak. Much of the change is attributed to reduction of the distance between the sample and the test animals, and reduction of the sample weight charged. Elimination of the connecting tube increased the relative toxicity of the polyurethane foams. The materials tested were flexible polyurethane foam, without and with fire retardant; rigid polyurethane foam with fire retardant; flexible polychloroprene foam; cotton, Douglas fir, red oak, hemlock, hardboard, particle board, polystyrene, and polymethyl methacrylate.

  16. Library and Information Skills Workbook.

    ERIC Educational Resources Information Center

    Vastine, Jim

    This workbook for a library and information skills course at the University of South Florida (USF), Tampa campus, contains the following sections: (1) syllabus; (2) tentative course outline; (3) statement of the course goal, general objectives, and objectives related to LC (Library of Congress) classification and the online catalog, dictionaries…

  17. 48 CFR 552.270-20 - Payment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., usable square footage delivered will be confirmed by either: (1) The Government's measurement of plans... of usable square footage stated in the lease. (c) If the amount of usable square footage delivered is... space delivered and the annual rental will be adjusted as follows: Usable square feet (USF) not...

  18. Overview of the Future Forest Webinar Series [Chapter 1

    Treesearch

    Sarah Hines; Megan Matonis

    2014-01-01

    The Future Forest Webinar Series was created to facilitate dialogue between scientists and managers about the challenges and opportunities created by the mountain pine beetle1 (MPB) epidemic. A core team of scientists and managers from the USFS Rocky Mountain Research Station and the Northern and Rocky Mountain Regions worked together to develop the format and content...

  19. Insulin signalling mechanisms for triacylglycerol storage.

    PubMed

    Czech, M P; Tencerova, M; Pedersen, D J; Aouadi, M

    2013-05-01

    Insulin signalling is uniquely required for storing energy as fat in humans. While de novo synthesis of fatty acids and triacylglycerol occurs mostly in liver, adipose tissue is the primary site for triacylglycerol storage. Insulin signalling mechanisms in adipose tissue that stimulate hydrolysis of circulating triacylglycerol, uptake of the released fatty acids and their conversion to triacylglycerol are poorly understood. New findings include (1) activation of DNA-dependent protein kinase to stimulate upstream stimulatory factor (USF)1/USF2 heterodimers, enhancing the lipogenic transcription factor sterol regulatory element binding protein 1c (SREBP1c); (2) stimulation of fatty acid synthase through AMP kinase modulation; (3) mobilisation of lipid droplet proteins to promote retention of triacylglycerol; and (4) upregulation of a novel carbohydrate response element binding protein β isoform that potently stimulates transcription of lipogenic enzymes. Additionally, insulin signalling through mammalian target of rapamycin to activate transcription and processing of SREBP1c described in liver may apply to adipose tissue. Paradoxically, insulin resistance in obesity and type 2 diabetes is associated with increased triacylglycerol synthesis in liver, while it is decreased in adipose tissue. This and other mysteries about insulin signalling and insulin resistance in adipose tissue make this topic especially fertile for future research.

  20. Forecast on the application of Japanese universal service fund to remote diagnosis for frozen section.

    PubMed

    Nakajima, Isao

    2010-12-01

    Due to the socioeconomic reason in Japan, some cancer patient is sometimes operated at a rural hospital where only several surgeons perform and no pathologist checks its malignancy. Therefore, the system of the remote diagnosis for frozen section has been standing up in this country for 7 years. In Japan, the USF has started from February 2007 to support only telecommunications operator's hardware (NTT's equipment such as digital switch board) in high cost areas, not for the reimbursement of the tariff of the public users, such as telepathology. To solve such social cormorant equality, when the USF and PAs were supported in the present quick frozen intraoperative telepathology diagnosis, the quality of the cancer treatment in rural area will be improved. Based on the past data of the Japanese telepathology with beta distribution function, it can be estimated that user terminals becomes five times more than present users with support of USF and PAs. Moreover, using VPN on the B'FLETS, the effect of other teleconsultations will spread to the nationwide.

  1. U.S. Forest Service Region 1 Lake Chemistry, NADP, and IMPROVE air quality data analysis

    Treesearch

    Jill Grenon; Mark Story

    2009-01-01

    This report was developed to address the need for comprehensive analysis of U.S. Forest Service (USFS) Region 1 air quality monitoring data. The monitoring data includes Phase 3 (long-term data) lakes, National Atmospheric Deposition Program (NADP), and Interagency Monitoring of Protected Visual Environments (IMPROVE). Annual and seasonal data for the periods of record...

  2. Variable Width Riparian Model Enhances Landscape and Watershed Condition

    NASA Astrophysics Data System (ADS)

    Abood, S. A.; Spencer, L.

    2017-12-01

    Riparian areas are ecotones that represent about 1% of USFS administered landscape and contribute to numerous valuable ecosystem functions such as wildlife habitat, stream water quality and flows, bank stability and protection against erosion, and values related to diversity, aesthetics and recreation. Riparian zones capture the transitional area between terrestrial and aquatic ecosystems with specific vegetation and soil characteristics which provide critical values/functions and are very responsive to changes in land management activities and uses. Two staff areas at the US Forest Service have coordinated on a two phase project to support the National Forests in their planning revision efforts and to address rangeland riparian business needs at the Forest Plan and Allotment Management Plan levels. The first part of the project will include a national fine scale (USGS HUC-12 digits watersheds) inventory of riparian areas on National Forest Service lands in western United States with riparian land cover, utilizing GIS capabilities and open source geospatial data. The second part of the project will include the application of riparian land cover change and assessment based on selected indicators to assess and monitor riparian areas on annual/5-year cycle basis.This approach recognizes the dynamic and transitional nature of riparian areas by accounting for hydrologic, geomorphic and vegetation data as inputs into the delineation process. The results suggest that incorporating functional variable width riparian mapping within watershed management planning can improve riparian protection and restoration. The application of Riparian Buffer Delineation Model (RBDM) approach can provide the agency Watershed Condition Framework (WCF) with observed riparian area condition on an annual basis and on multiple scales. The use of this model to map moderate to low gradient systems of sufficient width in conjunction with an understanding of the influence of distinctive landscape settings (landtype associations as employed in the USFS Terrestrial Condition Assessment) on finer lower order stream characteristics and patterns presents much promise.

  3. The sensitivity of relative toxicity rankings by the USF/NASA test method to some test variables

    NASA Technical Reports Server (NTRS)

    Hilado, C. J.; Labossiere, L. A.; Leon, H. A.; Kourtides, D. A.; Parker, J. A.; Hsu, M.-T. S.

    1976-01-01

    Pyrolysis temperature and the distance between the source and sensor of effluents are two important variables in tests for relative toxicity. Modifications of the USF/NASA toxicity screening test method to increase the upper temperature limit of pyrolysis, reduce the distance between the sample and the test animals, and increase the chamber volume available for animal occupancy, did not significantly alter rankings of relative toxicity of four representative materials. The changes rendered some differences no longer significant, but did not reverse any rankings. The materials studied were cotton, wool, aromatic polyamide, and polybenzimidazole.

  4. U.S. EPA, Pesticide Product Label, HOGUE AND KNOTT BLEACH, 09/26/1972

    EPA Pesticide Factsheets

    2011-04-14

    ... _, I' " , / I '. .t(:t. / /' / 11"" F"p,j( 11 'c, 0" '\\In (', ,( i tt·~~~d:: ... f·l I .... hln.jr. ('<1.,I,un Do not uSf' t, ,I,'! h 0 ':. i c i ear-, er ':. ! n (" 0 rl) bin at Ion \\fy! tt ...

  5. Effects of climate change on outdoor recreation [Chapter 10

    Treesearch

    Michael S. Hand; Jordan W. Smith; David L. Peterson; Nancy A. Brunswick; Carol P. Brown

    2018-01-01

    Federal agencies and other public land management agencies in Utah, Nevada, and southern Idaho provide and manage for numerous outdoor recreation opportunities. National forests in the U.S. Department of Agriculture Forest Service (USFS) Intermountain Region have nearly 19 million visits per year (table 10.1); adjacent National Park System units account for an...

  6. Interaction of the Transcription Start Site Core Region and Transcription Factor YY1 Determine Ascorbate Transporter SVCT2 Exon 1a Promoter Activity

    PubMed Central

    Qiao, Huan; May, James M.

    2012-01-01

    Transcription of the ascorbate transporter, SVCT2, is driven by two distinct promoters in exon 1 of the transporter sequence. The exon 1a promoter lacks a classical transcription start site and little is known about regulation of promoter activity in the transcription start site core (TSSC) region. Here we present evidence that the TSSC binds the multifunctional initiator-binding protein YY1. Electrophoresis shift assays using YY1 antibody showed that YY1 is present as one of two major complexes that specifically bind to the TSSC. The other complex contains the transcription factor NF-Y. Mutations in the TSSC that decreased YY1 binding also impaired the exon 1a promoter activity despite the presence of an upstream activating NF-Y/USF complex, suggesting that YY1 is involved in the regulation of the exon 1a transcription. Furthermore, YY1 interaction with NF-Y and/or USF synergistically enhanced the exon 1a promoter activity in transient transfections and co-activator p300 enhanced their synergistic activation. We propose that the TSSC plays a vital role in the exon 1a transcription and that this function is partially carried out by the transcription factor YY1. Moreover, co-activator p300 might be able to synergistically enhance the TSSC function via a “bridge” mechanism with upstream sequences. PMID:22532872

  7. 75 FR 10816 - Notice of Proposed Withdrawal Extension, In-Part, and Opportunity for Public Meeting; Oregon

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-09

    ... affects 59.78 acres of land withdrawn for the Panelli Seed Orchard. The USFS has determined the remaining... Panelli Seed Orchard (56 FR 11940 (1991)), for an additional 20-year term. PLO No. 6874 withdrew certain... Meridian Fremont National Forest Panelli Seed Orchard T. 37 S., R. 15 E., sec. 24, NE\\1/4\\SE\\1/4\\. [[Page...

  8. Complete Biallelic Insulation at the H19/Igf2 Imprinting Control Region Position Results in Fetal Growth Retardation and Perinatal Lethality

    PubMed Central

    Lee, Dong-Hoon; Singh, Purnima; Tsark, Walter M. K.; Szabó, Piroska E.

    2010-01-01

    Background The H19/Igf2 imprinting control region (ICR) functions as an insulator exclusively in the unmethylated maternal allele, where enhancer-blocking by CTCF protein prevents the interaction between the Igf2 promoter and the distant enhancers. DNA methylation inhibits CTCF binding in the paternal ICR allele. Two copies of the chicken β-globin insulator (ChβGI)2 are capable of substituting for the enhancer blocking function of the ICR. Insulation, however, now also occurs upon paternal inheritance, because unlike the H19 ICR, the (ChβGI)2 does not become methylated in fetal male germ cells. The (ChβGI)2 is a composite insulator, exhibiting enhancer blocking by CTCF and chromatin barrier functions by USF1 and VEZF1. We asked the question whether these barrier proteins protected the (ChβGI)2 sequences from methylation in the male germ line. Methodology/Principal Findings We genetically dissected the ChβGI in the mouse by deleting the binding sites USF1 and VEZF1. The methylation of the mutant versus normal (ChβGI)2 significantly increased from 11% to 32% in perinatal male germ cells, suggesting that the barrier proteins did have a role in protecting the (ChβGI)2 from methylation in the male germ line. Contrary to the H19 ICR, however, the mutant (mChβGI)2 lacked the potential to attain full de novo methylation in the germ line and to maintain methylation in the paternal allele in the soma, where it consequently functioned as a biallelic insulator. Unexpectedly, a stricter enhancer blocking was achieved by CTCF alone than by a combination of the CTCF, USF1 and VEZF1 sites, illustrated by undetectable Igf2 expression upon paternal transmission. Conclusions/Significance In this in vivo model, hypomethylation at the ICR position together with fetal growth retardation mimicked the human Silver-Russell syndrome. Importantly, late fetal/perinatal death occurred arguing that strict biallelic insulation at the H19/Igf2 ICR position is not tolerated in development. PMID:20838620

  9. MiRNA-362-3p induces cell cycle arrest through targeting of E2F1, USF2 and PTPN1 and is associated with recurrence of colorectal cancer.

    PubMed

    Christensen, Lise Lotte; Tobiasen, Heidi; Holm, Anja; Schepeler, Troels; Ostenfeld, Marie S; Thorsen, Kasper; Rasmussen, Mads H; Birkenkamp-Demtroeder, Karin; Sieber, Oliver M; Gibbs, Peter; Lubinski, Jan; Lamy, Philippe; Laurberg, Søren; Oster, Bodil; Hansen, Kristian Q; Hagemann-Madsen, Rikke; Byskov, Kristina; Ørntoft, Torben F; Andersen, Claus L

    2013-07-01

    Colorectal cancer (CRC) is one of the leading causes of cancer deaths in Western countries. A significant number of CRC patients undergoing curatively intended surgery subsequently develop recurrence and die from the disease. MicroRNAs (miRNAs) are aberrantly expressed in cancers and appear to have both diagnostic and prognostic significance. In this study, we identified novel miRNAs associated with recurrence of CRC, and their possible mechanism of action. TaqMan(®) Human MicroRNA Array Set v2.0 was used to profile the expression of 667 miRNAs in 14 normal colon mucosas and 46 microsatellite stable CRC tumors. Four miRNAs (miR-362-3p, miR-570, miR-148 a* and miR-944) were expressed at a higher level in tumors from patients with no recurrence (p<0.015), compared with tumors from patients with recurrence. A significant association with increased disease free survival was confirmed for miR-362-3p in a second independent cohort of 43 CRC patients, using single TaqMan(®) microRNA assays. In vitro functional analysis showed that over-expression of miR-362-3p in colon cancer cell lines reduced cell viability, and proliferation mainly due to cell cycle arrest. E2F1, USF2 and PTPN1 were identified as potential miR-362-3p targets by mRNA profiling of HCT116 cells over-expressing miR-362-3p. Subsequently, these genes were confirmed as direct targets by Luciferase reporter assays and their knockdown in vitro phenocopied the effects of miR-362-3p over-expression. We conclude that miR-362-3p may be a novel prognostic marker in CRC, and hypothesize that the positive effects of augmented miR-362-3p expression may in part be mediated through the targets E2F1, USF2 and PTPN1. Copyright © 2012 UICC.

  10. Wapiti and warblers: integrating game and nongame management in Idaho

    Treesearch

    C. R. Groves; J. W. Unsworth

    1993-01-01

    The primary concern of wildlife managers in the USDA Forest Service (USFS) and ldaho Department of Fish and Game (IDFG) is maintaining elk herds and quality elk hunting. As a result, nongame species like neotropical migratory landbirds do not receive much management attention. Cause for concern over this neglect are twofold: 1) forest fragmentation may be having...

  11. USF Sarasota-Manatee Work Plan Presentation for 2014-15 Board of Governors Review

    ERIC Educational Resources Information Center

    Board of Governors, State University System of Florida, 2014

    2014-01-01

    The State University System of Florida has developed three tools that aid in guiding the System's future: (1) The Board of Governors' new "Strategic Plan 2012-2025" is driven by goals and associated metrics that stake out where the System is headed; (2) The Board's "Annual Accountability Report" provides yearly tracking for how…

  12. Effects of climate change on nonforest vegetation [Chapter 7

    Treesearch

    Wayne G. Padgett; Matthew C. Reeves; Stanley G. Kitchen; David L. Tart; Jeanne C. Chambers; Cheri Howell; Mary E. Manning; John G. Proctor

    2018-01-01

    Nonforest ecosystems, as they are addressed in this chapter, contain woodland, shrubland, herbaceous, wetland, or riparian vegetation types. They are estimated to occupy over 30 million acres and 50 percent of the U.S. Department of Agriculture Forest Service (USFS) Intermountain Region (table 7.1). These diverse ecosystems range in elevation from desert floors to...

  13. 76 FR 79211 - Notice of Application for Proposed Withdrawal Extension and Opportunity for Public Meeting; Oregon

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-21

    ... Information Relay Service (FIRS) at 1-(800) 877-8339 to reach either of the named contacts during normal... herein by reference. The purpose of the proposed withdrawal extension is to continue the protection of... cooperative agreement would not provide adequate protection. The USFS would not need to acquire water rights...

  14. Copper-silver deposits of the Revett Formation, Montana and Idaho: origin and resource potential

    USGS Publications Warehouse

    Frost, Thomas P.; Zientek, Michael L.

    2006-01-01

    The Revett Formation of northern Idaho and western Montana contains major stratabound copper-silver deposits near Troy, Rock Creek, and Rock Lake, Montana. To help the U.S. Forest Service (USFS) meet its goal of integrating geoscience information into the land-planning process, U.S. Geological Survey (USGS) scientists recently completed a compilation of regional stratigraphy and mineralogy of the Revett Formation and a mineral resource assessment of Revett-type copper-silver deposits. The USGS assessment indicates that a large area of USFS-administered land in northwestern Montana and northern Idaho may contain significant undiscovered Revett-type copper-silver deposits.

  15. Energy Efficiency, Water Efficiency, and Renewable Energy Site Assessment: San Juan National Forest - Dolores Ranger District, Colorado

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kandt, Alicen J.; Kiatreungwattana, Kosol

    This report summarizes the results from an energy efficiency, water efficiency, and renewable energy site assessment of the Dolores Ranger District in the San Juan National Forest in Colorado. A team led by the U.S. Department of Energy's National Renewable Energy Laboratory (NREL) conducted the assessment with United States Forest Service (USFS) personnel on August 16-17, 2016, as part of ongoing efforts by USFS to reduce energy and water use and implement renewable energy technologies. The assessment is approximately an American Society of Heating, Refrigerating, and Air-Conditioning Engineers Level 2 audit and meets Energy Independence and Security Act requirements.

  16. The Histone Demethylase Jhdm1a Regulates Hepatic Gluconeogenesis

    PubMed Central

    Zou, Tie; Yao, Annie Y.; Cooper, Marcus P.; Boyartchuk, Victor; Wang, Yong-Xu

    2012-01-01

    Hepatic gluconeogenesis is required for maintaining blood glucose homeostasis; yet, in diabetes mellitus, this process is unrestrained and is a major contributor to fasting hyperglycemia. To date, the impacts of chromatin modifying enzymes and chromatin landscape on gluconeogenesis are poorly understood. Through catalyzing the removal of methyl groups from specific lysine residues in the histone tail, histone demethylases modulate chromatin structure and, hence, gene expression. Here we perform an RNA interference screen against the known histone demethylases and identify a histone H3 lysine 36 (H3K36) demethylase, Jhdm1a, as a key negative regulator of gluconeogenic gene expression. In vivo, silencing of Jhdm1a promotes liver glucose synthesis, while its exogenous expression reduces blood glucose level. Importantly, the regulation of gluconeogenesis by Jhdm1a requires its demethylation activity. Mechanistically, we find that Jhdm1a regulates the expression of a major gluconeogenic regulator, C/EBPα. This is achieved, at least in part, by its USF1-dependent association with the C/EBPα promoter and its subsequent demethylation of dimethylated H3K36 on the C/EBPα locus. Our work provides compelling evidence that links histone demethylation to transcriptional regulation of gluconeogenesis and has important implications for the treatment of diabetes. PMID:22719268

  17. Mxi1 is a repressor of the c-Myc promoter and reverses activation by USF.

    PubMed

    Lee, T C; Ziff, E B

    1999-01-08

    The basic region/helix-loop-helix/leucine zipper (B-HLH-LZ) oncoprotein c-Myc is abundant in proliferating cells and forms heterodimers with Max protein that bind to E-box sites in DNA and stimulate genes required for proliferation. A second B-HLH-LZ protein, Mxi1, is induced during terminal differentiation, and forms heterodimers with Max that also bind E-boxes but tether the mSin3 transcriptional repressor protein along with histone deacetylase thereby antagonizing Myc-dependent activation. We show that Mxi1 also antagonizes Myc by a second pathway, repression of transcription from the major c-myc promoter, P2. Repression was independent of Mxi1 binding to mSin3 but dependent on the Mxi1 LZ and COOH-terminal sequences, including putative casein kinase II phosphorylation sites. Repression targeted elements of the myc P2 promoter core (-35/+10), where it reversed transactivation by the constitutive transcription factor, USF. We show that Zn2+ induction of a stably transfected, metallothionein promoter-regulated mxi1 gene blocked the ability of serum to induce transcription of the endogenous c-myc gene and cell entry into S phase. Thus, induction of Mxi1 in terminally differentiating cells may block Myc function by repressing the c-myc gene P2 promoter, as well as by antagonizing Myc-dependent transactivation through E-boxes.

  18. Test of the Semi-Analytical Case 1 and Gelbstoff Case 2 SeaWiFS Algorithm with a Global Data Set

    NASA Technical Reports Server (NTRS)

    Carder, Kendall L.

    1997-01-01

    The algorithm-development activities at USF during the second half of 1997 have concentrated on data collection and theoretical modeling. Six abstracts were submitted for presentation at the AGU conference in San Diego, California during February 9-13, 1998. Four papers were submitted to JGR and Applied Optics for publication.

  19. Performance Monitoring of a Nearshore Berm at Ft. Myers Beach, Florida

    DTIC Science & Technology

    2013-08-01

    prototype designs. Coastal Zone ’93, American Society of Civil Engineers, pp. 2938 -2950. Andrassy, C . J. 1991. Monitoring of a nearshore disposal mound at...ER D C / CH L TR -1 3 -1 1 Performance Monitoring of a Nearshore Berm at Ft. Myers Beach, Florida: Final Report C oa st al a n d H yd...122  Appendix C : USF-CRL Survey Data: morphologic evolution during the first 2 years post construction

  20. Breaking the acoustic diffraction limit via nonlinear effect and thermal confinement for potential deep-tissue high-resolution imaging

    PubMed Central

    Yuan, Baohong; Pei, Yanbo; Kandukuri, Jayanth

    2013-01-01

    Our recently developed ultrasound-switchable fluorescence (USF) imaging technique showed that it was feasible to conduct high-resolution fluorescence imaging in a centimeter-deep turbid medium. Because the spatial resolution of this technique highly depends on the ultrasound-induced temperature focal size (UTFS), minimization of UTFS becomes important for further improving the spatial resolution USF technique. In this study, we found that UTFS can be significantly reduced below the diffraction-limited acoustic intensity focal size via nonlinear acoustic effects and thermal confinement by appropriately controlling ultrasound power and exposure time, which can be potentially used for deep-tissue high-resolution imaging. PMID:23479498

  1. [Linkage analysis of a family with familial hypertriglyceridemia].

    PubMed

    Tang, Xin; Lin, Ying; Liu, Bing; Ma, Shi; Yang, Yang; Yang, Zheng-lin

    2009-10-01

    To perform linkage analysis and mutation screening in a Chinese family with familial hpertriglyceridemia (FHTG). Thirty-two family members including 12 hypertriglyceridemia patients participated in the study. Genotyping and haplotype analysis for 22 subjects were performed using short tandem repeat (STR) microsatellite polymorphism markers on 16 candidate genes and/or loci related to lipid metabolism. Two of the sixteen known candidate genes, APOA2 and USF1 were screened for mutation by direct DNA sequencing. No linkage was found between the candidate genes/loci of APOA5, LIPI, RP1, APOC2, ABC1, LMF1, APOA1-APOC3-APOA4, LPL, APOB, CETP, LCAT, LDLR, APOE and the phenotype in this family. The two-point Lod scores (theta =0) were all less than-1.0 for all the markers tested. Linkage analysis suggested linkage to chromosome 1q23.3-24.2 between the disease phenotype and STR marker D1S194 with a two-point maximum Lod score of 2.44 at theta =0. Fine mapping indicated that the disease gene was localized to a 5.87 cM interval between D1S104 and D1S196. No disease-causing mutation was detected in the APOA2 and USF1 genes. The above mentioned candidate genes were excluded as the disease causing genes for this family. The results implied that there might be a novel gene/locus for FHTG on chromosome 1q23.3-1q24.2.

  2. Preliminary cellular-automata forecast of permit activity from 1998 to 2010, Idaho and Western Montana

    USGS Publications Warehouse

    Raines, G.L.; Zientek, M.L.; Causey, J.D.; Boleneus, D.E.

    2002-01-01

    For public land management in Idaho and western Montana, the U.S. Forest Service (USFS) has requested that the U.S. Geological Survey (USGS) predict where mineral-related activity will occur in the next decade. Cellular automata provide an approach to simulation of this human activity. Cellular automata (CA) are defined by an array of cells, which evolve by a simple transition rule, the automaton. Based on exploration trends, we assume that future exploration will focus in areas of past exploration. Spatial-temporal information about mineral-related activity, that is permits issued by USFS and Bureau of Land Management (BLM) in the last decade, and spatial information about undiscovered resources, provide a basis to calibrate a CA. The CA implemented is a modified annealed voting rule that simulates mineral-related activity with spatial and temporal resolution of 1 mi2 and 1 year based on activity from 1989 to 1998. For this CA, the state of the economy and exploration technology is assumed constant for the next decade. The calibrated CA reproduces the 1989-1998-permit activity with an agreement of 94%, which increases to 98% within one year. Analysis of the confusion matrix and kappa correlation statistics indicates that the CA underestimates high activity and overestimates low activity. Spatially, the major differences between the actual and calculated activity are that the calculated activity occurs in a slightly larger number of small patches and is slightly more uneven than the actual activity. Using the calibrated CA in a Monte Carlo simulation projecting from 1998 to 2010, an estimate of the probability of mineral activity shows high levels of activity in Boise, Caribou, Elmore, Lincoln, and western Valley counties in Idaho and Beaverhead, Madison, and Stillwater counties in Montana, and generally low activity elsewhere. ?? 2002 International Association for Mathematical Geology.

  3. Lessons from ten years of genome-wide association studies of asthma

    PubMed Central

    Vicente, Cristina T; Revez, Joana A; Ferreira, Manuel A R

    2017-01-01

    Twenty-five genome-wide association studies (GWAS) of asthma were published between 2007 and 2016, the largest with a sample size of 157242 individuals. Across these studies, 39 genetic variants in low linkage disequilibrium (LD) with each other were reported to associate with disease risk at a significance threshold of P<5 × 10−8, including 31 in populations of European ancestry. Results from analyses of the UK Biobank data (n=380 503) indicate that at least 28 of the 31 associations reported in Europeans represent true-positive findings, collectively explaining 2.5% of the variation in disease liability (median of 0.06% per variant). We identified 49 transcripts as likely target genes of the published asthma risk variants, mostly based on LD with expression quantitative trait loci (eQTL). Of these genes, 16 were previously implicated in disease pathophysiology by functional studies, including TSLP, TNFSF4, ADORA1, CHIT1 and USF1. In contrast, at present, there is limited or no functional evidence directly implicating the remaining 33 likely target genes in asthma pathophysiology. Some of these genes have a known function that is relevant to allergic disease, including F11R, CD247, PGAP3, AAGAB, CAMK4 and PEX14, and so could be prioritized for functional follow-up. We conclude by highlighting three areas of research that are essential to help translate GWAS findings into clinical research or practice, namely validation of target gene predictions, understanding target gene function and their role in disease pathophysiology and genomics-guided prioritization of targets for drug development. PMID:29333270

  4. Collaboration in Action: Office of Research and Development ...

    EPA Pesticide Factsheets

    The "Collaboration in Action: US EPA's Office of Research and Develop - Current Wildfire Research Program" was invited by the USDA's US Forest Service's Scientific Executive Committee to provide USFS scientific leadership active and potential future opportunities for cooperation/collaboration. Health impacts of wildfire smoke merit the attention and action of the US EPA and current research is supported in the ACE and SHC Research Programs. Wildland fire smoke research has taken on greater importance because the 1) contribution of wildland fire PM emissions relative to total US PM emissions is increasing, 2) the population health impacts are measurable and costly, 3) vulnerable and sensitive populations at-risk are increasing attendant to our aging U.S. population and the increasing area of the wildland-urban interface, and 4) health impacts of smoke could be minimized by identifying at-risk individuals and reducing their exposures. Examples are provided. The "Collaboration in Action: US EPA's Office of Research and Develop - Current Wildfire Research Program" was invited by the USDA's US Forest Service's Scientific Executive Committee to provide USFS scientific leadership active and potential future opportunities for cooperation/collaboration.

  5. A compilation of spatial digital databases for selected U.S. Geological Survey nonfuel mineral resource assessments for parts of Idaho and Montana

    USGS Publications Warehouse

    Carlson, Mary H.; Zientek, Michael L.; Causey, J. Douglas; Kayser, Helen Z.; Spanski, Gregory T.; Wilson, Anna B.; Van Gosen, Bradley S.; Trautwein, Charles M.

    2007-01-01

    This report compiles selected results from 13 U.S. Geological Survey (USGS) mineral resource assessment studies conducted in Idaho and Montana into consistent spatial databases that can be used in a geographic information system. The 183 spatial databases represent areas of mineral potential delineated in these studies and include attributes on mineral deposit type, level of mineral potential, certainty, and a reference. The assessments were conducted for five 1? x 2? quadrangles (Butte, Challis, Choteau, Dillon, and Wallace), several U.S. Forest Service (USFS) National Forests (including Challis, Custer, Gallatin, Helena, and Payette), and one Bureau of Land Management (BLM) Resource Area (Dillon). The data contained in the spatial databases are based on published information: no new interpretations are made. This digital compilation is part of an ongoing effort to provide mineral resource information formatted for use in spatial analysis. In particular, this is one of several reports prepared to address USFS needs for science information as forest management plans are revised in the Northern Rocky Mountains.

  6. Earth Science Capability Demonstration Project

    NASA Technical Reports Server (NTRS)

    Cobleigh, Brent

    2006-01-01

    A viewgraph presentation reviewing the Earth Science Capability Demonstration Project is shown. The contents include: 1) ESCD Project; 2) Available Flight Assets; 3) Ikhana Procurement; 4) GCS Layout; 5) Baseline Predator B Architecture; 6) Ikhana Architecture; 7) UAV Capability Assessment; 8) The Big Picture; 9) NASA/NOAA UAV Demo (5/05 to 9/05); 10) NASA/USFS Western States Fire Mission (8/06); and 11) Suborbital Telepresence.

  7. Implementation of the Ohio College Library Center's Proposed Serials Control Subsystem at the University of South Florida Library: Some Preliminary Considerations.

    ERIC Educational Resources Information Center

    Twitchell, Anne; Sprehn, Mary

    An evaluation of the Ohio College Library Center's (OCLC) proposed Serials Control Subsystem was undertaken to determine what effect the system would have on the operation of the Serials Department at the University of South Florida (USF) Library. The system would consist of three components: 1) claiming--identifying missing issues and generating…

  8. Characterization of BRCA2 Transcriptional Regulation

    DTIC Science & Technology

    2001-12-01

    tig of BRCA2 promoter construct and 0.1 and we verify the role of USF in regulation of basal activity of jig of pRL-TK Renilla luciferase vector...Promega) with 4 1 l of Fugene-6 the promoter. was used for each transfection. The pRL-TK Renilla luciferase activity was used to control for transfection...pCMV-CREB, pCMV-Myc, BRCA2 Reporter Constructs-A BAC clone (B489G) containing the 5’ and pCMV-Max. Firefly luciferase and Renilla luciferase assays

  9. Global Health

    MedlinePlus

    ... Global Health Security HIV & Tuberculosis Global Health Protection Malaria & Parasitic Diseases Immunization Other Diseases & Threats Travelers' Health ... Organization Strategy Partnerships Funding Latest News War on malaria: USF researchers wage battle against global disease 83 ...

  10. 76 FR 82296 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-30

    .... 20110431, Draft EIS, USFS, NV, Geothermal Leasing on the Humboldt-Toiyabe National Forest, To Facilitate the Development and Production of Geothermal Energy, Ely, Austin, Tonopah and Bridgeport Ranger...

  11. Managing Long-term Risks from Natural Hazards in a Dynamic Volcanic and Institutional Environment: The Spirit Lake Story

    NASA Astrophysics Data System (ADS)

    Grant, G.; Major, J. J.; Lewis, S.

    2016-12-01

    The 18 May 1980 eruption of Mount St. Helens, Washington, spawned a massive (109 m3) debris avalanche, a violent and extensive pyroclastic density current, lahars, pyroclastic flows, and ashfall. It fundamentally transformed the proximal landscape, and created potential secondary hazards that remain legacies of the eruption over 35 years later. The debris avalanche raised the level of Spirit Lake—a picturesque lake at the foot of the volcano—by 60 m and blocked its outlet. Abruptly, the lake went from charming to menacing, capable of releasing a potentially catastrophic outburst flood (108 m3) that could transform into a massive (109 m3) debris flow if rising lake water breached the blockage. To reduce risk of an uncontrolled breach, and under Presidential emergency declaration, the U.S. Army Corps of Engineers (USACE) bored a 2,590-m-long outlet tunnel through bedrock within the U.S. Forest Service (USFS)-administered Mount St. Helens National Volcanic Monument. Drainage through the tunnel maintains a safe lake level below a geologic contact in the blockage where seepage erosion could result in failure. Although the tunnel has performed its mission for over 30 years, episodic deformation has reduced its outlet capacity, necessitating expensive (>$1 million) repairs and closures which temporarily caused precarious lake rises, and prompted re-examination of the strategy to maintain a safe lake level. Here we discuss how federal researchers (USFS and U.S. Geological Survey) interact with Monument and USFS land managers, USACE, the National Academy of Sciences, and the public at large to develop and evaluate, under Congressional mandate, alternative strategies for reducing the risk of catastrophic flooding. Amidst this nexus of institutions, agendas, and perspectives, set against the backdrop of a rapidly evolving landscape subject to a trio of hazards (eruptions, earthquakes, floods), competing interests, costs, and natural risks must be balanced and managed.

  12. Algorithm-development activities

    NASA Technical Reports Server (NTRS)

    Carder, Kendall L.

    1994-01-01

    The task of algorithm-development activities at USF continues. The algorithm for determining chlorophyll alpha concentration, (Chl alpha) and gelbstoff absorption coefficient for SeaWiFS and MODIS-N radiance data is our current priority.

  13. HDAC5-LSD1 axis regulates antineoplastic effect of natural HDAC inhibitor sulforaphane in human breast cancer cells.

    PubMed

    Cao, Chunyu; Wu, Hao; Vasilatos, Shauna N; Chandran, Uma; Qin, Ye; Wan, Yong; Oesterreich, Steffi; Davidson, Nancy E; Huang, Yi

    2018-04-06

    Our recent studies have shown that cross-talk between histone deacetylase 5 (HDAC5) and lysine-specific demethylase 1 (LSD1) facilitates breast cancer progression. In this work, we demonstrated that regulatory activity at -356 to -100 bp promoter element plays a critical role in governing HDAC5 transcription. By using DNA affinity precipitation and mass spectrometry, we identified a group of factors that bind to this element. Among these factors, Upstream Transcription Factor 1 (USF1) was shown to play a critical role in controlling HDAC5 transcription. Through screening a panel of epigenetic modifying drugs, we showed that a natural bioactive HDAC inhibitor, sulforaphane, downregulated HDAC5 transcription by blocking USF1 activity. Sulforaphane facilitated LSD1 ubiquitination and degradation in an HDAC5-dependent manner. A comparative microarray analysis demonstrated a genome wide cooperative effect of HDAC5 and LSD1 on cancer-related gene expression. shRNA knockdown and sulforaphane inhibition of HDAC5/LSD1 exhibited similar effects on expression of HDAC5/LSD1 target genes. We also showed that coordinated cross-talk of HDAC5 and LSD1 is essential for the antitumor efficacy of sulforaphane. Combination treatment with sulforaphane and a potent LSD1 inhibitor resulted in synergistic growth inhibition in breast cancer cells, but not in normal breast epithelial cells. Furthermore, combined therapy with sulforaphane and LSD1 inhibitor exhibited superior inhibitory effect on MDA-MB-231 xenograft tumor growth. Taken together, our work demonstrates that HDAC5-LSD1 axis is an effective drug target for breast cancer. Inhibition of HDAC5-LSD1 axis with sulforaphane blocks breast cancer growth and combined treatment with LSD1 inhibitor improves the therapeutic efficacy of sulforaphane. © 2018 UICC.

  14. USF Equitable Distribution Act of 2013

    THOMAS, 113th Congress

    Sen. Ayotte, Kelly [R-NH

    2013-11-21

    Senate - 11/21/2013 Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  15. 75 FR 36386 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-25

    ..., Revised Draft EIS, USFS, 00, Uinta National Forest Oil and Gas Leasing, Implementation, Identify National Forest Systems Lands with Federal Mineral Rights, Wasatch, Utah, Juab, Tooele, and Sanpete Counties, UT...

  16. A novel polymorphism in the PAI-1 gene promoter enhances gene expression. A novel pro-thrombotic risk factor?

    PubMed

    Liguori, Renato; Quaranta, Sandro; Di Fiore, Rosanna; Elce, Ausilia; Castaldo, Giuseppe; Amato, Felice

    2014-12-01

    Plasminogen activator inhibitor-1 (PAI-1) is the major physiological inhibitor of tissue-type plasminogen activator in plasma and the most important regulator of the fibrinolytic pathway. The 4G/5G polymorphism (rs1799889) in the PAI-1 promoter is associated with altered PAI-1 transcription. We have identified a new 4G/5G allele, in which a T is inserted near the 4G tract or replaces a G in the 5G tract, forming a T plus 4G (T4G) region. This new variant was first identified in two women, one had experienced juvenile myocardial infarction, the other repeated miscarriage; both had increased PAI-1 plasma activity. In view of the important influence of this promoter region on PAI-1 protein plasma level, we performed in vitro evaluation of the effects of the T4G variant on the transcription activity of the PAI-1 gene promoter. In silico prediction analysis showed that presence of the T4G allele disrupts the E-Box region upstream of the T4G variant, altering the affinity of the target sequence for E-Box binding factors like upstream stimulatory factor-1 (USF-1). Basal T4G promoter activity was 50% higher compared to 4G and 5G variants, but it was less stimulated by USF-1 overexpression. We also analyzed the effects of IL-1β and IL-6 on the PAI-1 promoter activity of our three constructs and showed that the T4G variant was less affected by IL-1β than the other variants. These findings indicate that the T4G variant may be a novel risk factor for thrombotic events. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. 75 FR 58376 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ... Seastrand 626-574-5278. EIS No. 20100378, Draft Supplement, USFS, OR, North Fork Burnt River Mining Project.... 20100380, Final EIS, USACE, 00, Sabine-Neches Waterway Channel Improvement Project, Proposed Ocean Dredged...

  18. 78 FR 59677 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-27

    ..., Designation of the Atchafalaya River Bar Channel Ocean Dredged Material Disposal Site, Review Period Ends: 10.../2013, Contact: Paul Bradford 406-293-6211. EIS No. 20130282, Final EIS, USFS, WY, Clinker Mining...

  19. 75 FR 72823 - Environmental Impact Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-26

    ... Register. EIS No. 20100449, Draft EIS, USFS, MT, Stillwater Mining Revised Water Management Plans and BOE... and Reuse, Implementation, Brunswick, ME, Wait Period Ends: 12/27/2010, Contact: Thomas Stephan 215...

  20. 32 CFR 171.4 - Qualifications.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... of meeting the terms and conditions of a contract to deliver fire retardant by air. (a) Prior to... the USDA contract. (b) This requirement may not be delegated to the U.S. Forest Service (USFS). ...

  1. 75 FR 33299 - Environmental Impacts Statements; Notice Of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-11

    ...-963-0182. EIS No. 20100215, Final EIS, USFS, CO, Hermosa Park/Mitchell Lakes Land Exchange Project.../2010 to 07/ 26/2010. Dated: June 8, 2010. Ken Mittelholtz, Deputy Director, NEPA Compliance Division...

  2. Learning about Antiphospholipid Syndrome (APS)

    MedlinePlus

    ... rarediseasesnetwork.epi.usf.edu] An integrated group of academic medical centers, patient support organizations, and clinical research ... Diseases (4th ed.), Mackay IR, Rose NR, eds. Academic Press/Elsevier Science. 2006. Williams Hematology, 6th ed., ...

  3. 2003 Florida transportation almanac

    DOT National Transportation Integrated Search

    2003-12-01

    This publication is the third edition of the Florida Transportation Almanac, developed and produced by the : Center for Urban Transportation Research (CUTR) at the University of South Florida (USF) in Tampa. It : follows the original publication prod...

  4. Teaching marine science to the next generation: Innovative programs for 6th”8th Graders gain momentum

    NASA Astrophysics Data System (ADS)

    Tebbens, S. F.; Coble, P. G.; Greely, T.

    Three educational outreach programs designed for middle school students (grades 6, 7, and 8) by faculty at the University of South Florida (USF) Department of Marine Science are turning kids onto science. The programs are bringing marine science research and its various technologies into the classroom, where students follow up with hands-on activities. Project Oceanography (PO) is an interactive broadcast that exposes students to the concepts and tools of current marine science research. The Oceanography Camp for Girls (OCG) boosts girls' curiosity and interest in science and nature. And teachers become better equipped to present current marine science topics and technology to their students at the Teachers Oceanography Workshop (TOW). All of the programs created by USF are provided at no cost to students or their institutions.

  5. Estimates of carbon stored in harvested wood products from the United States forest service northern region, 1906-2010

    PubMed Central

    2012-01-01

    Background Global forests capture and store significant amounts of CO2 through photosynthesis. When carbon is removed from forests through harvest, a portion of the harvested carbon is stored in wood products, often for many decades. The United States Forest Service (USFS) and other agencies are interested in accurately accounting for carbon flux associated with harvested wood products (HWP) to meet greenhouse gas monitoring commitments and climate change adaptation and mitigation objectives. This paper uses the Intergovernmental Panel on Climate Change (IPCC) production accounting approach and the California Forest Project Protocol (CFPP) to estimate HWP carbon storage from 1906 to 2010 for the USFS Northern Region, which includes forests in northern Idaho, Montana, South Dakota, and eastern Washington. Results Based on the IPCC approach, carbon stocks in the HWP pool were increasing at one million megagrams of carbon (MgC) per year in the mid 1960s, with peak cumulative storage of 28 million MgC occurring in 1995. Net positive flux into the HWP pool over this period is primarily attributable to high harvest levels in the mid twentieth century. Harvest levels declined after 1970, resulting in less carbon entering the HWP pool. Since 1995, emissions from HWP at solid waste disposal sites have exceeded additions from harvesting, resulting in a decline in the total amount of carbon stored in the HWP pool. The CFPP approach shows a similar trend, with 100-year average carbon storage for each annual Northern Region harvest peaking in 1969 at 937,900 MgC, and fluctuating between 84,000 and 150,000 MgC over the last decade. Conclusions The Northern Region HWP pool is now in a period of negative net annual stock change because the decay of products harvested between 1906 and 2010 exceeds additions of carbon to the HWP pool through harvest. However, total forest carbon includes both HWP and ecosystem carbon, which may have increased over the study period. Though our emphasis is on the Northern Region, we provide a framework by which the IPCC and CFPP methods can be applied broadly at sub-national scales to other regions, land management units, or firms. PMID:22244260

  6. Potential of VIIRS Data for Regional Monitoring of Gypsy Moth Defoliation: Implications for Forest Threat Early Warning System

    NASA Technical Reports Server (NTRS)

    Spruce, Joseph P.; Ryan, Robert E.; Smoot, James C.; Prados, Donald; McKellip, Rodney; Sader. Steven A.; Gasser, Jerry; May, George; Hargrove, William

    2007-01-01

    A NASA RPC (Rapid Prototyping Capability) experiment was conducted to assess the potential of VIIRS (Visible/Infrared Imager/Radiometer Suite) data for monitoring non-native gypsy moth (Lymantria dispar) defoliation of forests. This experiment compares defoliation detection products computed from simulated VIIRS and from MODIS (Moderate Resolution Imaging Spectroradiometer) time series products as potential inputs to a forest threat EWS (Early Warning System) being developed for the USFS (USDA Forest Service). Gypsy moth causes extensive defoliation of broadleaved forests in the United States and is specifically identified in the Healthy Forest Restoration Act (HFRA) of 2003. The HFRA mandates development of a national forest threat EWS. This system is being built by the USFS and NASA is aiding integration of needed satellite data products into this system, including MODIS products. This RPC experiment enabled the MODIS follow-on, VIIRS, to be evaluated as a data source for EWS forest monitoring products. The experiment included 1) assessment of MODIS-simulated VIIRS NDVI products, and 2) evaluation of gypsy moth defoliation mapping products from MODIS-simulated VIIRS and from MODIS NDVI time series data. This experiment employed MODIS data collected over the approximately 15 million acre mid-Appalachian Highlands during the annual peak defoliation time frame (approximately June 10 through July 27) during 2000-2006. NASA Stennis Application Research Toolbox software was used to produce MODIS-simulated VIIRS data and NASA Stennis Time Series Product Tool software was employed to process MODIS and MODIS-simulated VIIRS time series data scaled to planetary reflectance. MODIS-simulated VIIRS data was assessed through comparison to Hyperion-simulated VIIRS data using data collected during gypsy moth defoliation. Hyperion-simulated MODIS data showed a high correlation with actual MODIS data (NDVI R2 of 0.877 and RMSE of 0.023). MODIS-simulated VIIRS data for the same date showed moderately high correlation with Hyperion-simulated VIIRS data (NDVI R2 of 0.62 and RMSE of 0.035), even though the datasets were collected about a half an hour apart during changing weather conditions. MODIS products (MOD02, MOD09, and MOD13) and MOD02-simulated VIIRS time series data were used to generate defoliation mapping products based on image classification and image differencing change detection techniques. Accuracy of final defoliation mapping products was assessed by image interpreting over 170 randomly sampled locations found on Landsat and ASTER data in conjunction with defoliation map data from the USFS. The MOD02-simulated VIIRS 400-meter NDVI classification produced a similar overall accuracy (87.28 percent with 0.72 Kappa) to the MOD02 250-meter NDVI classification (86.71 percent with 0.71 Kappa). In addition, the VIIRS 400-meter NDVI, MOD02 250-meter NDVI, and MOD02 500-meter NDVI showed good user and producer accuracies for the defoliated forest class (70 percent) and acceptable Kappa values (0.66). MOD02 and MOD02-simulated VIIRS data both showed promise as data sources for regional monitoring of forest disturbance due to insect defoliation.

  7. 76 FR 59125 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-23

    .... Markham 805-585-2150. EIS No. 20110317, Draft EIS, USFS, MT, Lonesome Wood Vegetation Management 2 Project... the 2006 FEIS Analysis and to Correct the Deficiencies that the Meister Panel Identified, Land and...

  8. Visitor Access and Transportation Guide.

    DOT National Transportation Integrated Search

    2011-09-30

    This visitor access and transportation guide presents opportunities to manage or improve circulation and travel patterns in areas managed by Federal Land Management Agencies (FLMAs), such as the National Park Service (NPS), U.S. Forest Service (USFS)...

  9. New theory for Mode I crack-tip dislocation emission

    NASA Astrophysics Data System (ADS)

    Andric, Predrag; Curtin, W. A.

    2017-09-01

    A material is intrinsically ductile under Mode I loading when the critical stress intensity KIe for dislocation emission is lower than the critical stress intensity KIc for cleavage. KIe is usually evaluated using the approximate Rice theory, which predicts a dependence on the elastic constants and the unstable stacking fault energy γusf for slip along the plane of dislocation emission. Here, atomistic simulations across a wide range of fcc metals show that KIe is systematically larger (10-30%) than predicted. However, the critical (crack tip) shear displacement is up to 40% smaller than predicted. The discrepancy arises because Mode I emission is accompanied by the formation of a surface step that is not considered in the Rice theory. A new theory for Mode I emission is presented based on the ideas that (i) the stress resisting step formation at the crack tip creates "lattice trapping" against dislocation emission such that (ii) emission is due to a mechanical instability at the crack tip. The new theory is formulated using a Peierls-type model, naturally includes the energy to form the step, and reduces to the Rice theory (no trapping) when the step energy is small. The new theory predicts a higher KIe at a smaller critical shear displacement, rationalizing deviations of simulations from the Rice theory. Specific predictions of KIe for the simulated materials, usually requiring use of the measured critical crack tip shear displacement due to complex material non-linearity, show very good agreement with simulations. An analytic model involving only γusf, the surface energy γs, and anisotropic elastic constants is shown to be quite accurate, serves as a replacement for the analytical Rice theory, and is used to understand differences between Rice theory and simulation in recent literature. The new theory highlights the role of surface steps created by dislocation emission in Mode I, which has implications not only for intrinsic ductility but also for crack tip twinning and fracture due to chemical interactions at the crack tip.

  10. Diadenosine Tetraphosphate Hydrolase Is Part of the Transcriptional Regulation Network in Immunologically Activated Mast Cells▿

    PubMed Central

    Carmi-Levy, Irit; Yannay-Cohen, Nurit; Kay, Gillian; Razin, Ehud; Nechushtan, Hovav

    2008-01-01

    We previously discovered that microphthalmia transcription factor (MITF) and upstream stimulatory factor 2 (USF2) each forms a complex with its inhibitor histidine triad nucleotide-binding 1 (Hint-1) and with lysyl-tRNA synthetase (LysRS). Moreover, we showed that the dinucleotide diadenosine tetraphosphate (Ap4A), previously shown to be synthesized by LysRS, binds to Hint-1, and as a result the transcription factors are released from their suppression. Thus, transcriptional activity is regulated by Ap4A, suggesting that Ap4A is a second messenger in this context. For Ap4A to be unambiguously established as a second messenger, several criteria have to be fulfilled, including the presence of a metabolizing enzyme. Since several enzymes are able to hydrolize Ap4A, we provided here evidence that the “Nudix” type 2 gene product, Ap4A hydrolase, is responsible for Ap4A degradation following the immunological activation of mast cells. The knockdown of Ap4A hydrolase modulated Ap4A accumulation, resulting in changes in the expression of MITF and USF2 target genes. Moreover, our observations demonstrated that the involvement of Ap4A hydrolase in gene regulation is not a phenomenon exclusive to mast cells but can also be found in cardiac cells activated with the β-agonist isoproterenol. Thus, we have provided concrete evidence establishing Ap4A as a second messenger in the regulation of gene expression. PMID:18644867

  11. Diadenosine tetraphosphate hydrolase is part of the transcriptional regulation network in immunologically activated mast cells.

    PubMed

    Carmi-Levy, Irit; Yannay-Cohen, Nurit; Kay, Gillian; Razin, Ehud; Nechushtan, Hovav

    2008-09-01

    We previously discovered that microphthalmia transcription factor (MITF) and upstream stimulatory factor 2 (USF2) each forms a complex with its inhibitor histidine triad nucleotide-binding 1 (Hint-1) and with lysyl-tRNA synthetase (LysRS). Moreover, we showed that the dinucleotide diadenosine tetraphosphate (Ap(4)A), previously shown to be synthesized by LysRS, binds to Hint-1, and as a result the transcription factors are released from their suppression. Thus, transcriptional activity is regulated by Ap(4)A, suggesting that Ap(4)A is a second messenger in this context. For Ap(4)A to be unambiguously established as a second messenger, several criteria have to be fulfilled, including the presence of a metabolizing enzyme. Since several enzymes are able to hydrolyze Ap(4)A, we provided here evidence that the "Nudix" type 2 gene product, Ap(4)A hydrolase, is responsible for Ap(4)A degradation following the immunological activation of mast cells. The knockdown of Ap(4)A hydrolase modulated Ap(4)A accumulation, resulting in changes in the expression of MITF and USF2 target genes. Moreover, our observations demonstrated that the involvement of Ap(4)A hydrolase in gene regulation is not a phenomenon exclusive to mast cells but can also be found in cardiac cells activated with the beta-agonist isoproterenol. Thus, we have provided concrete evidence establishing Ap(4)A as a second messenger in the regulation of gene expression.

  12. Kunsan AB, Korea. Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F

    DTIC Science & Technology

    1981-05-01

    A.. . .... .. . . . . . ... .. . ... _ GLOBAL CLI AT L-O Y BRA CH usF ,cCEILING VERSUS VISIBILITY 4 3 2 1 9 K U N S A N A K O 6 8 -7 0 97 3...77,.C 77.S 78,3 78,3 78*4 7805 78,5 7845 78,5 79,0 79,3S0 oo 70 74o 7417 791( 80.3 81. 8W. 81.6 NOV 81.9 81.9 81*9 1.9 82*3 82.6 > 35oo 74.5 79*1 796

  13. Update on the Caspar Creek watershed study

    Treesearch

    Peter Cafferata

    1987-01-01

    Readers of this Newsletter are aware that CDF and the USFS, through its Pacific Southwest Forest and Range Experiment Stationa at Arcata (PSW), are carrying out a long term cooperative watershed experiment in JDSF's Caspar Creek drainage.

  14. Impacts of dialysis transportation on Florida's coordinated public transportation programs.

    DOT National Transportation Integrated Search

    2014-04-01

    The National Center for Transit Research (NCTR) at the University of South Florida (USF) collected quantitative and qualitative data from Community Transportation Coordinators (CTCs) throughout Florida. An online survey and a series of personal inter...

  15. Florida public transportation anti-terrorism resource guide

    DOT National Transportation Integrated Search

    2001-10-01

    The Center for Urban Transportation (CUTR) at the University of South Florida (USF) assembled this guide to provide public transit agencies in Florida with information on current resources available to assist them with improving system security and g...

  16. USGS Field Activities 12BHM01, 12BHM02, 12BHM03, 12BHM04, and 12BHM05 on the West Florida Shelf, in February, April, May, June, and August 2012

    USGS Publications Warehouse

    Robbins, Lisa L.; Knorr, Paul O.; Daly, Kendra L.; Barrera, Kira E.

    2014-01-01

    As part of the U.S. Geological Survey (USGS) Coastal and Marine Geology Program project "Response of Florida Shelf Ecosystems to Climate Change" and in partnership with Kendra Daly, University of South Florida (USF), data on surface ocean carbonate chemistry were collected on five cruises along transects on the shallow inner west Florida shelf and northern Gulf of Mexico in 2012. Data from the 2011 cruises were also published (Robbins and others., 2013). The data collected allows the USGS, National Oceanic and Atmospheric Administration (NOAA), and USF scientists to map variations in ocean chemistry including carbonate saturation states along designated tracks. The USGS also partners with NOAA and the National Aeronautics and Space Administration (NASA) to model air-sea flux as part of a Gulf of Mexico Carbon Synthesis project led by NASA.

  17. Expansion of the Eclipse Digital Signal Processing System.

    DTIC Science & Technology

    1982-12-01

    8217eOU WIdT TO,. Fig 1 IE.ETZIM U2. E( 11 -4., - IULTIPI.E P * S WI) STPM FILTER (- PAWtfTEP FILE PFILE FILTER FILE: WILE FIEP. LENGTH 55 WINIIM OF WQS...Vg u I k114 2.2 1 .2 I 11 .l111 1.6 MICROCOPY RESOLUTION TEST CHART NA, ONA BURMAU OF SrANDARDS-1963 A b i -I i.i 1s Lt USF w191 UNITED STATES AIR...SIGNAL PROCESSING SYSTI.M I"’ 1 /GI,/V/H 2 D- I6 Gordon R. Alln ist Lt USAF" I . . SECURITY CLASSIFICATION OF THIS PAGE (When Data Entered) READ

  18. US Army Two-Surgeon Teams Operating in Remote Afghanistan - An Evaluation of Split-Based Forward Surgical Team Operations

    DTIC Science & Technology

    2009-04-01

    Patient Status ABD (%) Ext (%) Vasc (%) Uro (%) GYN (%) Thor (%) HN (%) Neuro (%) Burn (%) Other (%) Total USF (n 178) 6 (2.6) 125 (54.3) 3 (1.3) 0...Ext, extremity; Vasc, vascular; Uro , urological; GYN, gynecologic; Thor, thoracic; HN, head and neck; Neuro, neurologic. Table 8 Age, Sex, and...Shock Trauma Platoon with a similar patient cohort at Los Angeles County trauma center, found that 12.7% of patients treated by the Surgical Shock

  19. Environmental Assessment for the MQ-1 Predator and MQ-9 Reaper Unmanned Aircraft System (UAS) Second Formal Training Unit (FTU-2) Beddown

    DTIC Science & Technology

    2009-04-01

    agreement that the National Aeronautics and Space Administration ( NASA ) has in place. However, with close coordination among all users, C-band...land is owned and administered by the U.S. Bureau of Land Management ( BLM ). White Sands National Monument is located to the southwest. WSMR...for the base. Much of Edwards AFB is surrounded by government lands managed by the BLM , U.S. Forest Service (USFS) and State of California. The

  20. Development of EBM-CDSS (Evidence-Based Clinical Decision Support System) to AIG Prognostication in Terminally Ill Patients

    DTIC Science & Technology

    2016-03-01

    Mbah, PhD2*, Ambuj Kumar, MD, MPH3, Kim Sehwan, PhD4*, Ronald Schonwetter, MD5* and Benjamin Djulbegovic, MD, PhD6 1Center for Evidence - Based Medicine , University...of South Florida, Tampa, FL 2USF, Tampa, FL 3University of South Florida, College of Medicine, Center for Evidence Based Medicine , Tampa...4HPC healthcare, Tampa, FL 5HPC Healthcare, Tampa, FL 6Center for Evidence - Based Medicine & Health Outcomes Research, University of South

  1. p53 is a major component of the transcriptional and apoptotic program regulated by PI 3-kinase/Akt/GSK3 signaling.

    PubMed

    Nayak, G; Cooper, G M

    2012-10-11

    The phosphatidylinositol (PI) 3-kinase/Akt signaling pathway has a prominent role in cell survival and proliferation, in part, by regulating gene expression at the transcriptional level. Previous work using global expression profiling identified FOXOs and the E-box-binding transcription factors MITF and USF1 as key targets of PI 3-kinase signaling that lead to the induction of proapoptotic and cell cycle arrest genes in response to inhibition of PI 3-kinase. In this study, we investigated the role of p53 downstream of PI 3-kinase signaling by analyzing the effects of inhibition of PI 3-kinase in Rat-1 cells, which have wild-type p53, compared with Rat-1 cells expressing a dominant-negative p53 mutant. Expression of dominant-negative p53 conferred partial resistance to apoptosis induced by inhibition of PI 3-kinase. Global gene expression profiling combined with computational and experimental analysis of transcription factor binding sites demonstrated that p53, along with FOXO, MITF and USF1, contributed to gene induction in response to PI 3-kinase inhibition. Activation of p53 was mediated by phosphorylation of the histone acetyltransferase Tip60 by glycogen synthase kinase (GSK) 3, leading to activation of p53 by acetylation. Many of the genes targeted by p53 were also targeted by FOXO and E-box-binding transcription factors, indicating that p53 functions coordinately with these factors to regulate gene expression downstream of PI 3-kinase/Akt/GSK3 signaling.

  2. USGS field activities 11BHM03 and 11BHM04 on the west Florida shelf, Gulf of Mexico, September and November 2011

    USGS Publications Warehouse

    Robbins, Lisa L.; Knorr, Paul O.; Daly, Kendra L.; Barrera, Kira E.

    2014-01-01

    During September and November 2011 the (USGS), in cooperation with (USF), conducted geochemical surveys on the west Florida Shelf to investigate the effects of climate change on ocean acidification within the northern Gulf of Mexico, specifically, the effect of ocean acidification on marine organisms and habitats. The first cruise was conducted from September 20 to 28 (11BHM03) and the second was from November 2 to 4 (11BHM04). To view each cruise's survey lines, please see the Trackline page. Each cruise took place aboard the Research Vessel (R/V) Weatherbird II, a ship of opportunity led by Dr. Kendra Daly (USF), which departed from and returned to Saint Petersburg, Florida. Data collection included sampling of the surface and water column with lab analysis of pH, dissolved inorganic carbon (DIC) or total carbon dioxide (TCO2), and total alkalinity (TA). lLb analysis was augmented with a continuous flow-through system (referred to as sonde data) with a conductivity-temperature-depth (CTD) sensor, which also recorded salinity and pH. Corroborating the USGS data are the vertical CTD profiles (referred to as station samples) collected by USF. The CTD casts measured continuous vertical profiles of oxygen, chlorophyll fluorescence and optical backscatter. Discrete samples for nutrients, chlorophyll, and particulate organic carbon/nitrogen were also collected during the CTD casts. Two autonomous flow-through (AFT) instruments recorded pH and CO2 every 3-5 minutes on each cruise (referred to as AFT data).

  3. USGS field activities 11BHM01 and 11BHM02 on the west Florida shelf, Gulf of Mexico, May and June 2011

    USGS Publications Warehouse

    Robbins, Lisa L.; Knorr, Paul O.; Daly, Kendra L.; Taylor, Carl A.; Barrera, Kira E.

    2014-01-01

    During May and June 2011 the (USGS), in cooperation with (USF), conducted geochemical surveys on the west Florida Shelf to investigate the effects of climate change on ocean acidification within the northern Gulf of Mexico, specifically, the effect of ocean acidification on marine organisms and habitats. The first cruise was conducted from May 3 to 9 (11BHM01) and the second was from June 25 to 30 (11BHM02). To view each cruise's survey lines, please see the Trackline page. Each cruise took place aboard the Research Vessel (R/V) Weatherbird II, a ship of opportunity led by Dr. Kendra Daly (USF), which departed from and returned to Saint Petersburg, Florida. Data collection included sampling of the surface and water column with lab analysis of pH, dissolved inorganic carbon (DIC) or total carbon dioxide (TCO2), and total alkalinity (TA). lLb analysis was augmented with a continuous flow-through system (referred to as sonde data) with a conductivity-temperature-depth (CTD) sensor, which also recorded salinity and pH. Corroborating the USGS data are the vertical CTD profiles (referred to as station samples) collected by USF. The CTD casts measured continuous vertical profiles of oxygen, chlorophyll fluorescence and optical backscatter. Discrete samples for nutrients, chlorophyll, and particulate organic carbon/nitrogen were also collected during the CTD casts. Two autonomous flow-through (AFT) instruments recorded pH and CO2 every 3-5 minutes on each cruise (referred to as AFT data).

  4. Travel to Food : Transportation Barriers for the Food Insecure in Tampa Bay

    DOT National Transportation Integrated Search

    2017-09-01

    In partnership with the Center for Urban Transportation Research (CUTR) at the University of South Florida (USF), the Transportation Innovation Group informed practical transportation solutions aimed at improved food access in Tampa Bay (Hillsborough...

  5. Analysis of the Status and Impacts of NCTR Projects

    DOT National Transportation Integrated Search

    2012-08-01

    The National Center for Transit Research (NCTR) at the University of South Florida (USF) assessed the implementation status and identified the outcomes and impacts of the results of 30 Florida Department of Transportation -sponsored NCTR research pro...

  6. 78 FR 29063 - Survey of Urban Rates for Fixed Voice and Fixed Broadband Residential Services

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-17

    ... in alternative formats (computer diskette, large print, audio record, and Braille). Persons with... Company Name: Provider FRN (used on MONTH DAY, YEAR Form 477): Provider Study Area Code (if current USF...

  7. Crossing the Barriers: An Analysis of Land Access Barriers to Geothermal Development and Potential Improvement Scenarios

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Levine, Aaron L; Young, Katherine R

    Developers have identified many non-technical barriers to geothermal power development, including access to land. Activities required for accessing land, such as environmental review and private and public leasing can take a considerable amount of time and can delay or prevent project development. This paper discusses the impacts to available geothermal resources and deployment caused by land access challenges, including tribal and cultural resources, environmentally sensitive areas, biological resources, land ownership, federal and state lease queues, and proximity to military installations. In this analysis, we identified challenges that have the potential to prevent development of identified and undiscovered hydrothermal geothermal resources.more » We found that an estimated 400 MW of identified geothermal resource potential and 4,000 MW of undiscovered geothermal resource potential were either unallowed for development or contained one or more significant barriers that could prevent development at the site. Potential improvement scenarios that could be employed to overcome these barriers include (1) providing continuous funding to the U.S. Forest Service (USFS) for processing geothermal leases and permit applications and (2) the creation of advanced environmental mitigation measures. The model results forecast that continuous funding to the USFS could result in deployment of an additional 80 MW of geothermal capacity by 2030 and 124 MW of geothermal capacity by 2050 when compared to the business-as-usual scenario. The creation of advanced environmental mitigation measures coupled with continuous funding to the USFS could result in deployment of an additional 97 MW of geothermal capacity by 2030 and 152 MW of geothermal capacity by 2050 when compared to the business-as-usual scenario. The small impact on potential deployment in these improvement scenarios suggests that these 4,400 MW have other barriers to development in addition to land access. In other words, simply making more resources available for development does not increase deployment; however, impacts to deployment could increase when coupled with other improvements (e.g., permitting, market and/or technology improvements).« less

  8. 76 FR 14968 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-18

    .... 20110076, Draft Supplement, USFS, MT, Grizzly Vegetation and Transportation Management Project, Updated and... Management Actions, Three Rivers Ranger District, Kootenai National Forest, Lincoln County, MT, Comment..., Section 30 Limestone Mining Project, Proposal to Implement Mining Actions, Mystic Ranger District, Black...

  9. Ecosystem Services Derived from Headwater Catchments

    EPA Science Inventory

    We used data from the USEPA’s wadeable streams assessment (WSA), US Forest Service’s forest inventory and analysis (FIA), and select USFS experimental forests (EF) to investigate potential ecosystems services derived from headwater catchments. C, N, and P inputs to these catchmen...

  10. Auk Village Recreational Area : Conceptual Parking and Road Improvements Analysis.

    DOT National Transportation Integrated Search

    2008-07-01

    The U.S. Forest Service, Alaska region, Tongass National Forest (USFS), plans to make improvements to the Auk Village Recreation Area (AVRA or recreation area) and specifically Point Louisa Road (the road or roadway) which passes through the AVRA. Th...

  11. 77 FR 4318 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-27

    ..., Clearwater National Forest Travel Planning Project, Proposes to Manage Motorized and Mechanized Travel.../2012, Contact: Heather Berg (208) 476-4541. EIS No. 20120014, Revised Draft EIS, USFS, MT, East Deer Lodge Valley Landscape Restoration Management Project, To Conduct Landscape Restoration Management...

  12. Effect of test conditions on relative toxicity rankings of fifteen materials

    NASA Technical Reports Server (NTRS)

    Hilado, C. J.; Cumming, H. J.

    1977-01-01

    Fifteen materials were evaluated for relative toxicity of pyrolysis effluents, using different test conditions in the USF methodology. Wool fabrics were consistently among the most toxic materials, and polystyrene and polychloroprene flexible foam were consistently among the least toxic materials.

  13. 76 FR 78252 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-16

    ..., Rubicon Trail Easement and Resource Improvement Project, Construction and Operation, Right-of-Way Grant...: Andrea Catanzaro (409) 766-6346 EIS No. 20110421, Draft EIS, USFS, CA, Greys Mountain Ecological...--La Crosse Transmission System Improvement Project, Proposed Construction and Operation of a 345...

  14. Some Recent USF Studies at Volcanoes in Central America

    NASA Astrophysics Data System (ADS)

    McNutt, S. R.

    2014-12-01

    Scientists at the University of South Florida (USF) have been working in Central America for several decades. Efforts have focused on Physical Volcanology in Nicaragua, GPS in Costa Rica, and assessment of Geothermal projects in El Salvador, amongst others. Two years ago a Seismology Lab was established at USF. Personnel now include three Professors, a Post-Doc, and 4 graduate students. Seismic and GPS networks were installed at Telica Volcano, Nicaragua, in 2010 by Roman, LaFemina and colleagues. Data are recorded on site and recovered several times per year at this persistently restless volcano, which has rates of 5 to 1400 low frequency seismic events per day (Rodgers et al., submitted). Proposals have been submitted to install instruments on other Nicaraguan volcanoes, including seismometers, GPS, infrasound, and lightning sensors. This suite of instruments has proven to be very effective to study a range of volcanic processes. The proposals have not been successful to date (some are pending), and alternative funding sources are being explored. One interesting scientific issue is the presence of strong seasonal effects, specifically a pronounced rainy season and dry season and possible interaction between shallow volcanic processes and surface waters. We are also pursuing a variety of studies that are complementary to the instrumental efforts. One such study is examining volcanic earthquake swarms, with the focus to date on identifying diagnostics. One clear pattern is that peak rates often occur early in swarms, whereas the largest M event occurs late. Additional evidence suggests that the seismic source size grows systematically, especially for events with similar waveforms (families). Recognition of such patterns, linked to processes, may help to improve monitoring and better take advantage of instrumental data to reduce vulnerability from eruptions.

  15. In Silico Analysis of Gene Expression Network Components Underlying Pigmentation Phenotypes in the Python Identified Evolutionarily Conserved Clusters of Transcription Factor Binding Sites

    PubMed Central

    2016-01-01

    Color variation provides the opportunity to investigate the genetic basis of evolution and selection. Reptiles are less studied than mammals. Comparative genomics approaches allow for knowledge gained in one species to be leveraged for use in another species. We describe a comparative vertebrate analysis of conserved regulatory modules in pythons aimed at assessing bioinformatics evidence that transcription factors important in mammalian pigmentation phenotypes may also be important in python pigmentation phenotypes. We identified 23 python orthologs of mammalian genes associated with variation in coat color phenotypes for which we assessed the extent of pairwise protein sequence identity between pythons and mouse, dog, horse, cow, chicken, anole lizard, and garter snake. We next identified a set of melanocyte/pigment associated transcription factors (CREB, FOXD3, LEF-1, MITF, POU3F2, and USF-1) that exhibit relatively conserved sequence similarity within their DNA binding regions across species based on orthologous alignments across multiple species. Finally, we identified 27 evolutionarily conserved clusters of transcription factor binding sites within ~200-nucleotide intervals of the 1500-nucleotide upstream regions of AIM1, DCT, MC1R, MITF, MLANA, OA1, PMEL, RAB27A, and TYR from Python bivittatus. Our results provide insight into pigment phenotypes in pythons. PMID:27698666

  16. In Silico Analysis of Gene Expression Network Components Underlying Pigmentation Phenotypes in the Python Identified Evolutionarily Conserved Clusters of Transcription Factor Binding Sites.

    PubMed

    Irizarry, Kristopher J L; Bryden, Randall L

    2016-01-01

    Color variation provides the opportunity to investigate the genetic basis of evolution and selection. Reptiles are less studied than mammals. Comparative genomics approaches allow for knowledge gained in one species to be leveraged for use in another species. We describe a comparative vertebrate analysis of conserved regulatory modules in pythons aimed at assessing bioinformatics evidence that transcription factors important in mammalian pigmentation phenotypes may also be important in python pigmentation phenotypes. We identified 23 python orthologs of mammalian genes associated with variation in coat color phenotypes for which we assessed the extent of pairwise protein sequence identity between pythons and mouse, dog, horse, cow, chicken, anole lizard, and garter snake. We next identified a set of melanocyte/pigment associated transcription factors (CREB, FOXD3, LEF-1, MITF, POU3F2, and USF-1) that exhibit relatively conserved sequence similarity within their DNA binding regions across species based on orthologous alignments across multiple species. Finally, we identified 27 evolutionarily conserved clusters of transcription factor binding sites within ~200-nucleotide intervals of the 1500-nucleotide upstream regions of AIM1, DCT, MC1R, MITF, MLANA, OA1, PMEL, RAB27A, and TYR from Python bivittatus . Our results provide insight into pigment phenotypes in pythons.

  17. 77 FR 19281 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-30

    ..., FL, Central and Southern Florida Project, Broward County Water Preserve Areas, Updates Resulting from Policy Changes that occurred since 2007 Civil Works Board Approval, South Florida Water Management... for this project. EIS No. 20120089, Final EIS, USFS, CA, Greys Mountain Ecological Restoration Project...

  18. 76 FR 76972 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-09

    ... Supplement, USFS, 00, Programmatic--Kootenai, Idaho Panhandle, and Lolo National Forest Plan Amendments for... has been Identified as the Forest Service's Preferred Alternative, ID, WA, MT, Review Period Ends: 01... Basin Management Unit South Shore Fuel Reduction and Healthy Forest Restoration, To Manage Fuel...

  19. 78 FR 48672 - Environmental Impacts Statements;

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-09

    ... Bend Vegetation Management Project, Review Period Ends: 09/19/2013, Contact: Beth Peer 541-383- 4769... Supplement, USFS, ID, Salmon-Challis National Forest Travel Planning and OHV Designation Project, Comment... Mine Project, Comment Period Ends: 09/23/2013, Contact: Shiva Achet 575-234-5924 EIS No. 20130235...

  20. 78 FR 16500 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-15

    ... and Vegetation Management Project, Comment Period Ends: 04/29/2013, Contact: Marcy Anderson 541-419-0517. EIS No. 20130062, Draft EIS, USFS, NM, Roca Honda Mine Project, Exploration and Mine Development... Seco Riparian Sanctuary Unit Restoration and Pumping Plant/Fish Screen Facility Protection Project...

  1. 76 FR 75543 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-02

    ... Profile Zones (DFPZs), Lassen National Forest, Almanor Ranger District, Plumas County, CA, Comment Period... Treatment Activities, Updated and New Information, Idaho Panhandle National Forests, Priest Lake Ranger... (937) 257-5899. EIS No. 20110403, Draft EIS, USFS, CA, Creeks II Forest Restoration Project, Proposal...

  2. White River National Forest Hanging Lake transportation and operations study

    DOT National Transportation Integrated Search

    2017-05-01

    Hanging Lake is a recreation site located on land managed by the U.S. Forest Service (USFS) under the jurisdiction of the White River National Forests Eagle-Holy Cross Ranger District. Due to its increasing popularity over the past few years, the ...

  3. View of HiattStricklin property privy/outhouse. Note siding and shed design, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of Hiatt-Stricklin property privy/outhouse. Note siding and shed design, facing northwest - Hiatt Property, Privy-Outhouse, West bank of Woof Creek, 400 feet northwest of intersection of U.S.F.S. Roads 651 & 349, Placerville, Boise County, ID

  4. Potential of VIIRS Time Series Data for Aiding the USDA Forest Service Early Warning System for Forest Health Threats: A Gypsy Moth Defoliation Case Study

    NASA Technical Reports Server (NTRS)

    Spruce, Joseph P.; Ryan, Robert E.; McKellip, Rodney

    2008-01-01

    The Healthy Forest Restoration Act of 2003 mandated that a national forest threat Early Warning System (EWS) be developed. The USFS (USDA Forest Service) is currently building this EWS. NASA is helping the USFS to integrate remotely sensed data into the EWS, including MODIS data for monitoring forest disturbance at broad regional scales. This RPC experiment assesses the potential of VIIRS (Visible/Infrared Imager/Radiometer Suite) and MODIS (Moderate Resolution Imaging Spectroradiometer) data for contribution to the EWS. In doing so, the RPC project employed multitemporal simulated VIIRS and MODIS data for detecting and monitoring forest defoliation from the non-native Eurasian gypsy moth (Lymantria despar). Gypsy moth is an invasive species threatening eastern U.S. hardwood forests. It is one of eight major forest insect threats listed in the Healthy Forest Restoration Act of 2003. This RPC experiment is relevant to several nationally important mapping applications, including carbon management, ecological forecasting, coastal management, and disaster management

  5. Benjamin P. Flower (1962-2012)

    NASA Astrophysics Data System (ADS)

    Hastings, David W.; Shevenell, Amelia E.; Kennett, James P.

    2012-10-01

    Benjamin P. Flower, a gifted paleoceanographer and marine geologist, supportive colleague, and dedicated educator at the University of South Florida (USF) College of Marine Science (CMS) passed away on 1 July 2012 from complications related to a rare genetic immune dysfunction, Common Variable Immunodeficiency. He was 49 years old. During his brief illness, Ben's love of life and boundless high spirits were an inspiration to his family, friends, and colleagues. He exhibited remarkable courage and kept his sense of humor in face of adversity. Ben's intellectualism and enduring love of science remained intact, even in his last hours.

  6. Environmental Assessment for the MQ-1 Predator and MQ-9 Reaper Unmaned Aircraft System (UAS) Second Formal Training Unit (FTU-2) Beddown

    DTIC Science & Technology

    2009-04-01

    Administration ( NASA ) has in place. However, with close coordination among all users, C-band would be available until the primary means to control UAS shifts...Management ( BLM ). White Sands National Monument is located to the southwest. WSMR surrounds the Monument and borders Holloman AFB to the north, west...lands managed by the BLM , U.S. Forest Service (USFS) and State of California. The large population areas of Los Angeles County are located 60 miles

  7. Three-dimensional dictionary-learning reconstruction of (23)Na MRI data.

    PubMed

    Behl, Nicolas G R; Gnahm, Christine; Bachert, Peter; Ladd, Mark E; Nagel, Armin M

    2016-04-01

    To reduce noise and artifacts in (23)Na MRI with a Compressed Sensing reconstruction and a learned dictionary as sparsifying transform. A three-dimensional dictionary-learning compressed sensing reconstruction algorithm (3D-DLCS) for the reconstruction of undersampled 3D radial (23)Na data is presented. The dictionary used as the sparsifying transform is learned with a K-singular-value-decomposition (K-SVD) algorithm. The reconstruction parameters are optimized on simulated data, and the quality of the reconstructions is assessed with peak signal-to-noise ratio (PSNR) and structural similarity (SSIM). The performance of the algorithm is evaluated in phantom and in vivo (23)Na MRI data of seven volunteers and compared with nonuniform fast Fourier transform (NUFFT) and other Compressed Sensing reconstructions. The reconstructions of simulated data have maximal PSNR and SSIM for an undersampling factor (USF) of 10 with numbers of averages equal to the USF. For 10-fold undersampling, the PSNR is increased by 5.1 dB compared with the NUFFT reconstruction, and the SSIM by 24%. These results are confirmed by phantom and in vivo (23)Na measurements in the volunteers that show markedly reduced noise and undersampling artifacts in the case of 3D-DLCS reconstructions. The 3D-DLCS algorithm enables precise reconstruction of undersampled (23)Na MRI data with markedly reduced noise and artifact levels compared with NUFFT reconstruction. Small structures are well preserved. © 2015 Wiley Periodicals, Inc.

  8. View of McKenzieRichey covered well showing log and lumber construction ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of McKenzie-Richey covered well showing log and lumber construction and shingles, facing southeast - McKenzie Property, Covered Well, North Bank of Sailor Gulch, 750 feet northwest of intersection of U.S.F.S. Roads 651 & 349, Placerville, Boise County, ID

  9. Design and evaluation of steel bridges with double composite action

    DOT National Transportation Integrated Search

    2010-02-01

    This report presents findings from a cooperative USF/URS/FDOT research study undertaken to develop design rules for : double composite steel bridges. In the study, a 48 ft long, 16 ft wide, 4 ft. 10 in. deep trapezoidal HPS 70W box section : desig...

  10. 75 FR 21625 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ...: Christopher Worthington 775-635-4000. EIS No. 20100136, Final EIS, USFS, 00, Nebraska National Forests and..., Buffalo Gap National Grassland, Oglala National Grassland, Samuel R. McKelvie National Forest, and the Pine Ridge and Bessey Units of the Nebraska National Forest, Fall River, Custer, Pennington, Jackson...

  11. The potential for alternative transportation at Chimney Rock, San Juan National Forest

    DOT National Transportation Integrated Search

    2012-05-30

    Increased visitation at Chimney Rock in the San Juan National Forest in southwest Colorado has led to increasing interest in the addition of a shuttle system. Piloting a shuttle system at Chimney Rock is a relatively low-cost option that the USFS cou...

  12. USAC Annual Report, 2008

    ERIC Educational Resources Information Center

    Universal Service Administrative Company, 2009

    2009-01-01

    The Universal Service Administrative Company (USAC) is an independent, not-for-profit corporation designated as the administrator of the federal Universal Service Fund (USF) by the Federal Communications Commission (FCC). USAC administers the Universal Service Fund and the four Universal Service programs: High Cost, Low Income, Rural Health Care,…

  13. 76 FR 19772 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-08

    ... Barker 208-735-2072. EIS No. 20110101, Final EIS, USFS, CO, Big Moose Vegetation Management Project... Salvage Project, Proposal to Treat Timer Harvest, Prescribe Fire, and Mechanical Thinning, Uinta-Wasatch... No. 20110107, Final EIS, FHWA, IL, Illinois 336 Corridor Project, (Federal Aid Primary Route 315...

  14. View of McKenzieRichey barn showing shed design, rolled roofing and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of McKenzie-Richey barn showing shed design, rolled roofing and wood shed roof, facing southwest - McKenzie Property, Barn, North Bank of Sailor Gulch, 750 feet northwest of intersection of U.S.F.S. Roads 651 & 349, Placerville, Boise County, ID

  15. Long-term trends in fire behavior and changes in population at risk

    EPA Science Inventory

    Long-term trends in fire behavior and changes in population at risk Rappold AG, Peterson GC, US EPA Matt Jolly, USFS Air pollution regulations and technological advances have successfully reduced emissions of air pollutants from many anthropogenic sources in recent decades. Duri...

  16. Human immunodeficiency virus type 1 Nef protein inhibits NF-kappa B induction in human T cells.

    PubMed Central

    Niederman, T M; Garcia, J V; Hastings, W R; Luria, S; Ratner, L

    1992-01-01

    Human immunodeficiency virus type 1 (HIV-1) can establish a persistent and latent infection in CD4+ T lymphocytes (W. C. Greene, N. Engl. J. Med. 324:308-317, 1991; S. M. Schnittman, M. C. Psallidopoulos, H. C. Lane, L. Thompson, M. Baseler, F. Massari, C. H. Fox, N. P. Salzman, and A. S. Fauci, Science 245:305-308, 1989). Production of HIV-1 from latently infected cells requires host cell activation by T-cell mitogens (T. Folks, D. M. Powell, M. M. Lightfoote, S. Benn, M. A. Martin, and A. S. Fauci, Science 231:600-602, 1986; D. Zagury, J. Bernard, R. Leonard, R. Cheynier, M. Feldman, P. S. Sarin, and R. C. Gallo, Science 231:850-853, 1986). This activation is mediated by the host transcription factor NF-kappa B [G. Nabel and D. Baltimore, Nature (London) 326:711-717, 1987]. We report here that the HIV-1-encoded Nef protein inhibits the induction of NF-kappa B DNA-binding activity by T-cell mitogens. However, Nef does not affect the DNA-binding activity of other transcription factors implicated in HIV-1 regulation, including SP-1, USF, URS, and NF-AT. Additionally, Nef inhibits the induction of HIV-1- and interleukin 2-directed gene expression, and the effect on HIV-1 transcription depends on an intact NF-kappa B-binding site. These results indicate that defective recruitment of NF-kappa B may underlie Nef's negative transcriptional effects on the HIV-1 and interleukin 2 promoters. Further evidence suggests that Nef inhibits NF-kappa B induction by interfering with a signal derived from the T-cell receptor complex. Images PMID:1527859

  17. Population estimates for the Toiyabe population of the Columbia spotted frog (Rana luteiventris), 2004–10

    USGS Publications Warehouse

    Adams, Michael J.; Mellison, Chad; Galvan, Stephanie K.

    2013-01-01

    The Toiyabe population of Columbia spotted frogs (Rana luteiventris, hereafter "Toiyabe frogs") is a geographically isolated population located in central Nevada (fig. 1). The Toiyabe population is part of the Great Basin Distinct Population Segment of Columbia spotted frogs, and is a candidate for listing under the Endangered Species Act (U.S. Fish and Wildlife Service, 2011). The cluster of breeding sites in central Nevada represents the southernmost extremity of the Columbia spotted frogs' known range (Funk and others, 2008). Toiyabe frogs are known to occur in seven drainages in Nye County, Nevada: Reese River, Cow Canyon Creek, Ledbetter Canyon Creek, Cloverdale Creek, Stewart Creek, Illinois Creek, and Indian Valley Creek. Most of the Toiyabe frog population resides in the Reese River, Indian Valley Creek, and Cloverdale Creek drainages (fig. 1; Nevada Department of Wildlife, 2003). Approximately 90 percent of the Toiyabe frogs' habitat is on public land. Most of the public land habitat (95 percent) is managed by the U.S. Forest Service (USFS), while the Bureau of Land Management (BLM) manages the remainder. Additional Toiyabe frog habitat is under Yomba Shoshone Tribal management and in private ownership (Nevada Department of Wildlife, 2003). The BLM, USFS, Nevada Department of Wildlife (NDOW), Nevada Natural Heritage Program (NNHP), Nye County, and U.S Fish and Wildlife Service (USFWS) have monitored the Toiyabe population since 2004 using mark and recapture surveys (Nevada Department of Wildlife, 2004). The USFWS contracted with the U.S. Geological Survey (USGS) to produce population estimates using these data.

  18. 77 FR 3265 - Information Collection Being Reviewed by the Federal Communications Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-23

    ... business concerns with fewer than 25 employees. The FCC may not conduct or sponsor a collection of... of a currently approved collection. Respondents: Business or other for-profit entities. Number of... previous burden estimates. On November 18, 2011, the Commission adopted the USF/ICC Transformation Order...

  19. Coweeta (CWT) [USFS, LTER

    Treesearch

    Chelcy Miniat

    2013-01-01

    The EcoTrends Editorial Committee sorted through vase amounts of historical and ongoing data from 50 ecological sites in the continental United States including Alaska, several islands, and Antarctica to present in a logical format the variables commonly collected. This report presents a subset of data and variables from these sites and illustrates through detailed...

  20. Collaboration in Action: Office of Research and Development (ORD) at the US Environmental Protection Agency (USEPA)-Current Wildfire Program

    EPA Science Inventory

    The "Collaboration in Action: US EPA's Office of Research and Develop - Current Wildfire Research Program" was invited by the USDA's US Forest Service's Scientific Executive Committee to provide USFS scientific leadership active and potential future opportunities for co...

  1. Technical Assessment of Roaring Fork Transit Authority ITS / Related Alternative Transportation Concepts on the White River National Forest.

    DOT National Transportation Integrated Search

    2007-12-12

    At the request of the U.S. Department of Agriculture Forest Service (USFS), the U.S. DOT : Volpe Center conducted a review of the status of Intelligent Transportation Systems (ITS) : planning by the Roaring Fork Transit Authority (RFTA). The assessme...

  2. Summary of southeastern group breakout sessions

    Treesearch

    Bob Ford; Charles P. Nicholson

    1993-01-01

    The breakout sessions held by the southeastern representatives at the Partners In Flight meeting in Colorado were extremely well attended Most states were represented, as well as several federal agencies (including USFS, USFWS, TVA, EPA), and non-government organizations. Two sessions were held, one to discuss a strategy of management by...

  3. USAC Annual Report, 2009

    ERIC Educational Resources Information Center

    Universal Service Administrative Company, 2009

    2009-01-01

    This paper presents the activities of the Universal Service Administrative Company (USAC) for 2009. The past year was one of accomplishment for USAC. USAC implemented a host of advances in operations, infrastructure, and outreach in an effort to continue to improve collection and disbursement of the Universal Service Fund (USF) support and to…

  4. US forest service technical cooperation visit Badia Rangeland and irrigation analysis

    USDA-ARS?s Scientific Manuscript database

    A US Forest Service (USFS) team comprised of a rangeland management advisor, a dryland water resource, and irrigation specialist, and a Middle East program specialist visited Jordan to provide technical assistance to the Ministry of Agriculture-Water Harvesting Directorate (MoA) and the Hashemite Fu...

  5. 77 FR 60986 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-05

    .../2012, Contact: Liana Liu 360-753-9553. EIS No. 20120312, Final EIS, USFS, NV, Geothermal Leasing on the Humboldt-Toiyabe National Forest, To Facilitate the Development and Production of Geothermal Energy, Ely..., Contact: Jerald Weaver 360-378-2223. EIS No. 20120314, Draft EIS, WAPA, WY, Hermosa West Wind Energy...

  6. Introduction

    Treesearch

    Deborah J. Chavez; Patricia C. Winter; James D. Absher

    2008-01-01

    In 1987, the Pacific Southwest Research Station (PSW) of the U.S. Department of Agriculture, Forest Service (USFS), chartered a research work unit to examine outdoor recreation in the wildland-urban interface. The need for the work unit was identified by the four forest supervisors in southern California, from the Angeles National Forest, the Cleveland National Forest...

  7. 77 FR 9652 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-17

    ... Road-Related Impacts to Wildlife, Fish, Soil, and Water Resources and Restoration of 2010 Forest Plan..., Amendment 18A to the Fishery Management Plan for the Snapper-Grouper Fishery of the South Atlantic Region...-9235. EIS No. 20120034, Draft EIS, USFS, CA, Harris Vegetation Management Project, To Improve Forest...

  8. Development and Experimental Verification of a High Resolution, Tunable LIDAR Computer Simulation Model for Atmospheric Laser Remote Sensing

    NASA Astrophysics Data System (ADS)

    Wilcox, William Edward, Jr.

    1995-01-01

    A computer program (LIDAR-PC) and associated atmospheric spectral databases have been developed which accurately simulate the laser remote sensing of the atmosphere and the system performance of a direct-detection Lidar or tunable Differential Absorption Lidar (DIAL) system. This simulation program allows, for the first time, the use of several different large atmospheric spectral databases to be coupled with Lidar parameter simulations on the same computer platform to provide a real-time, interactive, and easy to use design tool for atmospheric Lidar simulation and modeling. LIDAR -PC has been used for a range of different Lidar simulations and compared to experimental Lidar data. In general, the simulations agreed very well with the experimental measurements. In addition, the simulation offered, for the first time, the analysis and comparison of experimental Lidar data to easily determine the range-resolved attenuation coefficient of the atmosphere and the effect of telescope overlap factor. The software and databases operate on an IBM-PC or compatible computer platform, and thus are very useful to the research community for Lidar analysis. The complete Lidar and atmospheric spectral transmission modeling program uses the HITRAN database for high-resolution molecular absorption lines of the atmosphere, the BACKSCAT/LOWTRAN computer databases and models for the effects of aerosol and cloud backscatter and attenuation, and the range-resolved Lidar equation. The program can calculate the Lidar backscattered signal-to-noise for a slant path geometry from space and simulate the effect of high resolution, tunable, single frequency, and moderate line width lasers on the Lidar/DIAL signal. The program was used to model and analyze the experimental Lidar data obtained from several measurements. A fixed wavelength, Ho:YSGG aerosol Lidar (Sugimoto, 1990) developed at USF and a tunable Ho:YSGG DIAL system (Cha, 1991) for measuring atmospheric water vapor at 2.1 μm were analyzed. The simulations agreed very well with the measurements, and also yielded, for the first time, the ability to easily deduce the atmospheric attentuation coefficient, alpha, from the Lidar data. Simulations and analysis of other Lidar measurements included that of a 1.57 mu m OPO aerosol Lidar system developed at USF (Harrell, 1995) and of the NASA LITE (Laser-in-Space Technology Experiment) Lidar recently flown in the Space shuttle. Finally, an extensive series of laboratory experiments were made with the 1.57 μm OPO Lidar system to test calculations of the telescope/laser overlap and the effect of different telescope sizes and designs. The simulations agreed well with the experimental data for the telescope diameter and central obscuration test cases. The LIDAR-PC programs are available on the Internet from the USAF Lidar Home Page Web site, http://www.cas.usf.edu/physics/lidar.html/.

  9. TREEGRAD: a grading program for eastern hardwoods

    Treesearch

    J.W. Stringer; D.W. Cremeans

    1991-01-01

    Assigning tree grades to eastern hardwoods is often a difficult task for neophyte graders. Recently several "dichotomous keys" have been developed for training graders in the USFS hardwood tree grading system. TREEGRAD uses the Tree Grading Algorithm (TGA) for determining grades from defect location data and is designed to be used as a teaching aid.

  10. 5. Photocopy of site plan drawing, with later amendments dhowing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Photocopy of site plan drawing, with later amendments dhowing original USFS building shceduled for removal, Annex moved to present location, and addition to Warehouse (from the U.S. Forest Service, Wenatchee National Forest) Date Unkown - U.S. Forest Service Chelan Ranger Station, 428 West Woodin Avenue, Chelan, Chelan County, WA

  11. Federal Subsidies of Advanced Telecommunications for Schools, Libraries, and Health Care Providers. CBO Papers.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Congressional Budget Office.

    The Telecommunications Act of 1996 directs the Federal Communications Commission (FCC) to include support for advanced telecommunications--such as the Internet and computer networking--for elementary and secondary schools, public libraries, and nonprofit rural health care providers among the Universal Service Fund (USF) mandates. In its plan, the…

  12. Assessing the Usefulness of SAT and ACT Tests in Minority Admissions

    ERIC Educational Resources Information Center

    Micceri, Theodore

    2010-01-01

    This study sought to determine whether the use of standardized test scores contributes any useful information regarding First Time in College (FTIC) students' probable success at USF, using more detailed analysis of underrepresented minorities and women, who Micceri (2009) shows, experience substantial negative bias relative to males and whites on…

  13. 77 FR 21522 - Lake Tahoe Basin Management Unit and Tahoe National Forest, CA; Calpeco 625 and 650 Electrical...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-10

    ... DEPARTMENT OF AGRICULTURE Forest Service Lake Tahoe Basin Management Unit and Tahoe National... hereby given that the USDA Forest Service (USFS), Lake Tahoe Basin Management Unit (LTBMU), together with... reliable electrical transmission system for the north Lake Tahoe area, while accommodating currently...

  14. The Mammoth-June Ecosystem Management Project, Inyo National Forest

    Treesearch

    Connie Millar

    1996-01-01

    The Sierra Nevada Ecosystem Project (SNEP) case-study assessmentof the Mammoth-June Ecosystem Management Project(MJEMP) was undertaken to review and analyze the efficacy of alocal landscape analysis in achieving ecosystem-management objectivesin the Sierra Nevada. Of primary interest to SNEP was applicationof the new U.S. Forest Service (USFS) regional process...

  15. 78 FR 53754 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-30

    ... Everglades Planning Project, Comment Period Ends: 10/15/2013, Contact: Gretchen Ehlinger 904 232-1682. EIS No. 20130251, Final EIS, USFS, MN, BWCAW Non-native Invasive Plant Management Project, Review Period Ends: 10... Project, Comment Period Ends: 10/15/2013, Contact: Pete Gomben 801-999-2182. EIS No. 20130255, Draft EIS...

  16. 77 FR 49792 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-17

    ....epa.gov/compliance/nepa/ . Weekly receipt of Environmental Impact Statements Filed 08/06/2012 Through..., Comment Period Ends: 10/01/2012, Contact: Brian Hasselbach 406-441-3908. EIS No. 20120266, Draft EIS, USFS... Ends: 10/01/2012, Contact: Harold Dyer 719-852-6215. EIS No. 20120267, Draft EIS, USN, VA, Outdoor...

  17. 76 FR 75900 - Notice of Application for Withdrawal Extension and Opportunity for Public Meeting; Wyoming

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-05

    ... of National Forest System land in the Shoshone National Forest from mining in order to protect the... of National Forest System land in the Shoshone National Forest from location and entry under the... of Land Management, Interior. ACTION: Notice. SUMMARY: The United States Forest Service (USFS) has...

  18. 76 FR 45848 - Notice of Application for Withdrawal and Public Meeting; Oregon

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-01

    ... approximately 5,610 acres of National Forest System lands, for a period of 5 years in aid of legislation to... period, the following described National Forest System lands from location and entry under the United... Management, Interior. ACTION: Notice. SUMMARY: The United States Forest Service (USFS) has filed an...

  19. 76 FR 22340 - Further Inquiry Into Tribal Issues Relating to Establishment of a Mobility Fund

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-21

    ... Fund (USF) to create a Mobility Fund which would employ a market-based, reverse auction mechanism to... Into Tribal Issues Relating to Establishment of a Mobility Fund AGENCY: Federal Communications... consideration by the Federal Communication Commission in connection with the proposed creation of a new Mobility...

  20. Second interagency conference on research in the watersheds

    Treesearch

    Kelly Elder; Kate Dwire; Robert Hubbard; Charles Rhoades; Sandra Ryan; Mike Young; Laurie Porth; Mark Dixon; Angue Goodbody

    2006-01-01

    The report comprises papers and abstracts from the Second Interagency Conference on Research in the Watersheds, May 16-18, Coweeta Hydrologic Laboratory, Otto NC. Authors from several agencies (e.g., USDA ARS, US-EPA, USFS) and the private sector contributed papers on topics ranging from new technology and analytical procedures, modeling, and hydrologic responses to...

  1. 77 FR 7152 - Mobility Fund Phase I Auction Scheduled for September 27, 2012; Comment Sought on Competitive...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-10

    ... application deadlines and other dates related to Auction 901 after considering comments provided in response... must file an application for support. Only after review of the application to confirm compliance with... for support to Tribal lands. 7. The USF/ICC Transformation Order established application, performance...

  2. Relationships between harvest of American ginseng and hardwood timber production

    Treesearch

    Stephen P. Prisley; James Chamberlain; Michael McGuffin

    2012-01-01

    The goal of this research was to quantify the relationship between American ginseng (Panax quinquefolius) and timber inventory and harvest. This was done through compilation and analysis of county-level data from public datasets: ginseng harvest data from U.S. Fish and Wildlife Service, US Forest Service (USFS) forest inventory and analysis (FIA)...

  3. Road 151, Santa Fe National Forest : observations, considerations, and recommendations from the Interagency Transportation Assistance Group (TAG)

    DOT National Transportation Integrated Search

    2016-04-18

    This report for the U.S. Forest Service (USFS) documents the observations and findings of a transportation assistance group (TAG) study of Forest Road 151 on the Santa Fe National Forest near Abiquiu, New Mexico. Over the course of a three day site v...

  4. Collaborative Research and Watershed Management for Optimization of Forest Road Best Management Practices

    Treesearch

    Mark S. Riedel; James M. Vose

    2003-01-01

    The Coweeta Hydrologic Laboratory, USFS Southern Research Station, worked with state and local agencies and various organizations to provide guidance and tools to reduce sedimentation and facilitate restoration of the 1900km2 Conasauga River watershed in northern Georgia and southern Tennessee. The Conasauga River has the most diverse aquatic...

  5. 77 FR 62215 - Extension of the Comment Period: The Village at Wolf Creek Access Project Draft Environmental...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-12

    ... DEPARTMENT OF AGRICULTURE Forest Service Extension of the Comment Period: The Village at Wolf Creek Access Project Draft Environmental Impact Statement AGENCY: Forest Service, USDA. ACTION... (USFS), Rio Grande National Forest announces the extension of the comment period for the Village at Wolf...

  6. Recreation visitor research: studies of diversity

    Treesearch

    Deborah J. Chavez; Patricia L. Winter; James D. Absher

    2008-01-01

    In 1987, the Pacific Southwest Research Station (PSW) of the U.S. Department of Agriculture Forest Service (USFS) chartered a research work unit to examine outdoor recreation in the wildland-urban interface. The new work unit was established to address the needs of the increasingly diverse recreation visitors to national forests. The four forest supervisors in southern...

  7. Special Deliveries: Towards a Methodology for Generous Fulfillment of Special Collections Interlibrary Loan Requests

    ERIC Educational Resources Information Center

    Griffin, Melanie; Schmidt, LeEtta

    2017-01-01

    This article explores the implementation of special collections interlibrary loan policies and procedures at the University of South Florida (USF), focusing particularly on the development of policies related to physically loaning published materials, and traces the development of these policies through a pilot project to routinized…

  8. 78 FR 26261 - Connect America Fund; Developing a Unified Intercarrier Compensation Regime

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-06

    ... acts pursuant to its delegated authority to clarify and correct certain rules in response to recent... 51.915 and 51.917, to file data with the Universal Service Administrative Company (USAC), the... consistent with the USF/ICC Transformation Order. IX. Procedural Matters A. Paperwork Reduction Act 33. This...

  9. A multi-scale analysis of streamflow response to changes in evapotranspiration and soil hydrology in the Blue Ridge Mountains

    EPA Science Inventory

    A large amount of research exploring the relationship between watershed forest cover and streamflow quantity has been conducted in the southern Blue Ridge Mountains, particularly in association with the USFS Coweeta Hydrologic Laboratory and the Coweeta LTER. However, a clear ans...

  10. Reproducibility of polycarbonate reference material in toxicity evaluation

    NASA Technical Reports Server (NTRS)

    Hilado, C. J.; Huttlinger, P. A.

    1981-01-01

    A specific lot of bisphenol A polycarbonate has been used for almost four years as the reference material for the NASA-USF-PSC toxicity screening test method. The reproducibility of the test results over this period of time indicate that certain plastics may be more suitable reference materials than the more traditional cellulosic materials.

  11. Risk complexity and the wildland firefighter

    Treesearch

    Ivan Pupulidy

    2012-01-01

    Between 2000 and 2010 the US Forest Service and the Department of the Interior experienced 82 wildland fire fatalities. Our most recent organizational focus has been to eliminate fatalities. The chief of the USFS, in a letter to all employees, asked us to "suspend disbelief" with regard to the concept of a "zero fatality organization". This plea...

  12. Command Performance The USFS presents its annual Termiticide Report for 2014

    Treesearch

    Thomas Shelton; Donald Fye; Juliet Tang; Mark Mankowski

    2015-01-01

    For a termiticide to reach the American market where it's available for purchase by pest management professionals (PMPs), it must be federally registered by the U.S. Environmental Protection Agency (EPA). Chemical manufacturers wishing to register their products as a termiticide submit a registration package to the EPA containing fairly standard, nontarget...

  13. 78 FR 12269 - Wireline Competition Bureau Seeks Updates and Corrections to TelcoMaster Table for Connect...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-22

    ... Competition Bureau Seeks Updates and Corrections to TelcoMaster Table for Connect America Cost Model AGENCY... centers to particular holding companies for purposes of Connect America Phase II implementation. DATES... companies for purposes of Connect America Phase II implementation. 2. The USF/ICC Transformation Order, 76...

  14. Expanding the Use of Online Remote Electron Microscopy in the Classroom to Transform Undergraduate Geoscience Education: Successes and Strategies for Increasing Student and Faculty Engagement

    NASA Astrophysics Data System (ADS)

    Hickey-Vargas, R.; Holbik, S. P.; Ryan, J. G.; MacDonald, J. H., Jr.; Beck, M.

    2015-12-01

    Geoscience faculty at the University of South Florida (USF), Florida Gulf Coast University (FCGU), Valencia College (VC) and Florida International University (FIU) have teamed to construct, test and disseminate geoscience curricula in which microbeam analytical instruments are operated by undergraduates, with data gathered in the classroom in real-time over the internet. Activities have been developed for courses Physical Geology, Oceanography, Earth Materials, Mineralogy/Petrology and Stratigraphy using the Scanning Electron Microscope (SEM) and Electron Probe Microanalyzer (EPMA) housed in the Florida Center for Analytical Electron Microscopy (FCAEM; https://fcaem.fiu.edu) at FIU. Students and faculty send research materials such as polished rock sections and microfossil mounts to FCAEM to be examined during their scheduled class and lab periods. Student control of both decision-making and selection of analytical targets is encouraged. The objective of these activities is to move students from passive learning to active, self-directed inquiry at an early stage in their undergraduate career, while providing access to advanced instruments that are not available at USF, FGCU and VC. These strategies strongly facilitate student interest in undergraduate research making use of these instruments and one positive outcome to date is an increased number of students undertaking independent research projects. Prior research by USF PI Jeff Ryan indicated that various barriers related to instrument access and use hindered interested geoscience faculty in making use of these tools and strategies. In the current project, post-doctoral researcher Dr. Sven Holbik acts as a facilitator, working directly with faculty from other institutions one-on-one to provide initial training and support, including on-site visits to field check classroom technology when needed. Several new educators and institutions will initiate classroom activities using FCAEM instrumentation this Fall.

  15. The Eating Disorder Assessment for DSM-5 (EDA-5): Development and Validation of a Structured Interview for Feeding and Eating Disorders

    PubMed Central

    Sysko, Robyn; Glasofer, Deborah R.; Hildebrandt, Tom; Klimek, Patrycja; Mitchell, James E.; Berg, Kelly C.; Peterson, Carol B.; Wonderlich, Stephen A.; Walsh, B. Timothy

    2016-01-01

    Objective Existing measures for DSM-IV eating disorder diagnoses have notable limitations, and there are important differences between DSM-IV and DSM-5 feeding and eating disorders. This study developed and validated a new semi-structured interview, the Eating Disorders Assessment for DSM-5 (EDA-5). Method Two studies evaluated the utility of the EDA-5. Study 1 compared the diagnostic validity of the EDA-5 to the Eating Disorder Examination (EDE) and evaluated the test-retest reliability of the new measure. Study 2 compared the diagnostic validity of an EDA-5 electronic application (“app”) to clinician interview and self-report assessments. Results In Study 1, the kappa for EDE and EDA-5 eating disorder diagnoses was 0.74 across all diagnoses (n= 64), with a range of κ=0.65 for Other Specified Feeding or Eating Disorder (OSFED)/Unspecified Feeding or Eating Disorder (USFED) to κ=0.90 for Binge Eating Disorder (BED). The EDA-5 test-retest kappa coefficient was 0.87 across diagnoses. For Study 2, clinical interview versus “app” conditions revealed a kappa of 0.83 for all eating disorder diagnoses (n=71). Across individual diagnostic categories, kappas ranged from 0.56 for OSFED/USFED to 0.94 for BN. Discussion High rates of agreement were found between diagnoses by EDA-5 and the EDE, and EDA-5 and clinical interviews. As this study supports the validity of the EDA-5 to generate DSM-5 eating disorders and the reliability of these diagnoses, the EDA-5 may be an option for the assessment of Anorexia Nervosa, Bulimia Nervosa, and BED. Additional research is needed to evaluate the utility of the EDA-5 in assessing DSM-5 feeding disorders. PMID:25639562

  16. 78 FR 72889 - Notice of Public Information Collection(s) Being Reviewed by the Federal Communications...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-04

    ... burden for small business concerns with fewer than 25 employees. The FCC may not conduct or sponsor a... FCC Form 525. Type of Review: Revision of a currently approved collection. Respondents: Business or... Rulemaking, 26 FCC Rcd 17663 (2011) (USF/ICC Transformation Order); see also Connect America Fund et al., WC...

  17. Special Inspector General for Iraq Reconstruction Quarterly Report and Semiannual Report to the United States Congress

    DTIC Science & Technology

    2010-01-30

    Kickback Act and making false statements 7/20/2007 14 months in prison; 2 years supervised release; $6,000 fine; $17,964 restitution Anthony Martin ...usf-iraq.com/news/press-briefings/generals-david- petrae - us-and-ray-odierno-take-media-questions-following-the- establishment-of-united-states-forces

  18. Forest Land Ownership in the Conterminous United States [map

    Treesearch

    Mark D. Nelson; Greg C. Liknes

    2007-01-01

    Patterns of public and private forestland ownership vary across the United States. For example, two-thirds of western forestland is publicly owned, mostly by federal agencies such as the U.S. Forest Service (USFS), Bureau of Land Management, and National Park Service. However, more than 80 percent of eastern forestland is privately owned. Private forestland is further...

  19. Advancing individual tree biomass prediction: assessment and alternatives to the component ratio method

    Treesearch

    Aaron Weiskittel; Jereme Frank; David Walker; Phil Radtke; David Macfarlane; James Westfall

    2015-01-01

    Prediction of forest biomass and carbon is becoming important issues in the United States. However, estimating forest biomass and carbon is difficult and relies on empirically-derived regression equations. Based on recent findings from a national gap analysis and comprehensive assessment of the USDA Forest Service Forest Inventory and Analysis (USFS-FIA) component...

  20. Combining FIA plot data with topographic variables: Are precise locations needed?

    Treesearch

    Stephen P. Prisley; Huei-Jin Wang; Philip J Radtke; John Coulston

    2009-01-01

    Plot data from the USFS FIA program could be combined with terrain variables to attempt to explain how terrain characteristics influence forest growth, species composition, productivity, fire behavior, wildlife habitat, and other phenomena. While some types of analyses using FIA data have been shown to be insensitive to precision of plot locations, it has been...

  1. National forests

    Treesearch

    Linda A. Joyce; Geoffry M. Blate; Jeremy S. Littell; Steven G. McNulty; Constance I. Millar; Susanne C. Moser; Ronald P. Neilson; Kathy O' Halloran; David L. Peterson

    2008-01-01

    The National Forest System (NFS) is composed of 155 national forests (NFs) and 20 national grasslands (NGs), which encompass a wide range of ecosystems, harbor much of the nation’s biodiversity, and provide myriad goods and services. The mission of the U.S. Forest Service (USFS), which manages the NFS, has broadened from water and timber to sustaining ecosystem health...

  2. 75 FR 21036 - Notice of Proposed Withdrawal Extension and Opportunity for Public Meeting; Oregon

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-22

    ...,400 acres of National Forest System land from mining in order to protect the major anadromous fish...: Bureau of Land Management, Interior. ACTION: Notice. SUMMARY: The United States Forest Service (USFS) has..., from location and entry under the United States mining laws (30 U.S.C. ch. 2), for an additional 20...

  3. Transportation Observations, Considerations, and Recommendations for White Mountain National Forest Provided by the Interagency Transportation Assistance Group (TAG) Plymouth, New Hampshire June 27-29, 2007

    DOT National Transportation Integrated Search

    2007-06-27

    Mountain National Forest by the interagency Transportation Assistance Group (TAG) was conducted June 27-29, 2007, on behalf of the U.S. Forest Service (USFS). This TAG report was prepared subsequent to the site visit and documents the conditions obse...

  4. Effects of climate change on recreation in the Northern Rockies Region [Chapter 10

    Treesearch

    Michael S. Hand; Megan Lawson

    2018-01-01

    Outdoor recreation is an important benefit provided by Federally managed and other public lands throughout the Rocky Mountains. National forests in the Forest Service, U.S. Department of Agriculture (USFS) Northern Region and Greater Yellowstone Area (a region hereafter called the Northern Rockies region) have an estimated 13.3 million visits per year; Yellowstone,...

  5. Making Decisions: Using Electronic Data Collection to Re-Envision Reference Services at the USF Tampa Libraries

    ERIC Educational Resources Information Center

    Todorinova, Lily; Huse, Andy; Lewis, Barbara; Torrence, Matt

    2011-01-01

    Declining reference statistics, diminishing human resources, and the desire to be more proactive and embedded in academic departments, prompted the University of South Florida Library to create a taskforce for re-envisioning reference services. The taskforce was charged with examining the staffing patterns at the desk and developing…

  6. The Stephen F. Austin Experimental Forest

    Treesearch

    Cary C. Russell; Ronald E. Thill; David L. Kulhavy

    2002-01-01

    On December 14, 1944, the Seventy-Eighth United States Congress passed a bill that authorized the transfer of 2,560 acres in Nacogdoches County, Texas, to the research branch of the United States Forest Service (USFS). This land became the Stephen F. Austin Experimental Forest (SFAEF) on September 19. 1945. One of eighty-one federal experimental forests and ranges...

  7. CFES--California Fire Economics Simulator: A Computerized System for Wildland Fire Protection Planning

    Treesearch

    Jeremy S. Fried; J. Keith Gilless; Robert E. Martin

    1987-01-01

    The University of California's Department of Forestry and Resource Management, under contract with the California Department of Forestry and Fire Protection, has developed and released the first version of the California Fire Economics Simulator (CFES). The current release is adapted from the Initial Action Assessment component of the USFS's National Fire...

  8. Trends in land and water available for outdoor recreation

    Treesearch

    Lloyd C. Irland; Thomas Rumpf

    1980-01-01

    A data base for assessing the availability of land for outdoor recreation does not exist. Information on related issues such as vandalism, easements, and land posting is scanty. Construction of a data base for assessing land availability should be a high priority for USFS and HCRS, and for SCORP's and the RPA and RCA assessments.

  9. Field validation of Burned Area Reflectance Classification (BARC) products for post fire assessment

    Treesearch

    Andrew T. Hudak; Peter R. Robichaud; Jeffery B. Evans; Jess Clark; Keith Lannom; Penelope Morgan; Carter Stone

    2004-01-01

    The USFS Remote Sensing Applications Center (RSAC) and the USGS EROS Data Center (EDC) produce Burned Area Reflectance Classification (BARC) maps for use by Burned Area Emergency Rehabilitation (BAER) teams in rapid response to wildfires. BAER teams desire maps indicative of soil burn severity, but photosynthetic and nonphotosynthetic vegetation also influences the...

  10. Law enforcement officers in the USDA forest service

    Treesearch

    Deborah J. Chavez; Joanne F. Tynon

    2006-01-01

    This paper reports results fiom the first in a series of studies evaluating perceptions of law enforcement officers (LEOs) in the US Forest Service (USFS). It is a follow-up to previous qualitative studies conducted to learn more about crime and violence in national forests and the impacts on recreation visitation and management, and test key characteristics of success...

  11. Rehabilitating Afghanistan's natural resources

    Treesearch

    George Hernandez

    2011-01-01

    The Soviet Union invaded Afghanistan in late 1979. During the next 23 years, the war between the Mujahideen Resistance and the Soviet forces, the ensuing civil war, and eventual take over by the Taliban caused enormous harm to the natural resources of Afghanistan. In 2003, the USDA Forest Service (USFS) was asked by the USDA Foreign Agricultural Service to provide...

  12. Building Bridges: Perspectives on Partnership and Collaboration from the US Forest Service Tribal Relations Program

    Treesearch

    Michael J. Dockry; Sophia A. Gutterman; Mae A. Davenport

    2017-01-01

    American Indian tribes have inherent rights to national forestland and resources codified in treaties, the US Constitution, statutes, Presidential Executive Orders, and case law. These rights require a government-togovernment relationship between each tribe and the US Forest Service (USFS), which recognizes federal trust responsibilities and tribal sovereignty. This is...

  13. Influences on USFS District Rangers' Decision to Authorize Wildland Fire Use

    Treesearch

    Martha A. Williamson

    2006-01-01

    United States wildland fire policy and program reviews in 1995 and 2000 required reduction of hazardous fuel and recognition of fire as a natural process. Although an existing policy, Wildland Fire Use (WFU), permitted managing natural ignitions to meet resource benefits, most fuel reduction is still achieved through mechanical treatments and prescribed burning....

  14. 77 FR 13319 - Information Collection Being Submitted to the Office of Management and Budget (OMB) for Emergency...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-06

    ...), via fax at 202-395-5167 or via Internet at [email protected] and to Judith B. Herman, Federal Communications Commission, via the Internet at [email protected] . To submit your PRA... waste, fraud and abuse of the Universal Service Fund (USF or Fund). Among other things, the Lifeline...

  15. Role of the U.S. Forest Service: Helping forests, grasslands, and wildlife adapt to shifts in climate

    Treesearch

    Monica S. Tomosy; Frank R. Thompson; Douglas Boyce

    2011-01-01

    This fall, the U.S. Forest Service (USFS) will release a comprehensive new guidebook designed to help managers develop climate adaptation options for National Forests (Peterson et al. 2011, in press). The adaptation process is based on partnerships between local resource managers and scientists working collaboratively to understand potential climate change effects,...

  16. 6. View of HiattStricklin House showing north gable back and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. View of Hiatt-Stricklin House showing north gable back and east side. Note the porches, shsutters and chimney. The shiny squares on the siding are metal pieces to repair woodpecker holes, facing southwest. - Hiatt Property, House, West bank of Woof Creek, 400 feet northwest of intersection of U.S.F.S. Roads 651 & 349, Placerville, Boise County, ID

  17. Chapter 17: Forecasting wildfire suppression expenditures for the United States Forest Service

    Treesearch

    Karen L. Abt; Jeffrey P. Prestemon; Krista Gebert

    2008-01-01

    The wildland fire management organization of the United States Forest Service (USFS) operates under policy and budget legacies that began nearly 100 years ago and a forest fuel situation that is all too current. The confluence of these three factors contributes to increased burning and fire fighting costs for the agency, and increased concern from both the U.S....

  18. Forecasting wildfire suppression expenditures for the United States Forest Service

    Treesearch

    Karen L. Abt; Jeffrey P. Prestemon; Krista Gebert

    2008-01-01

    The wildland fire management organization of the United States Forest Service (USFS) operates under policy and budget legacies that began nearly -100 years ago and a forest fuel situation that is all too current. The confluence of these three factors contributes to increased burning and firefighting costs for the agency, and increased concern from both the U.S....

  19. The soil indicator of forest health in the Forest Inventory and Analysis Program

    Treesearch

    Michael C. Amacher; Charles H. Perry

    2010-01-01

    Montreal Process Criteria and Indicators (MPCI) were established to monitor forest conditions and trends to promote sustainable forest management. The Soil Indicator of forest health was developed and implemented within the USFS Forest Inventory and Analysis (FIA) program to assess condition and trends in forest soil quality in U.S. forests regardless of ownership. The...

  20. Recommendations to the U.S. Forest Service: Alternative Transportation at El Yunque National Forest Provided by the Interagency Transportation Assistance Group (TAG) Rio Grande, Puerto Rico October 15-19, 2007.

    DOT National Transportation Integrated Search

    2007-10-15

    At the request of the U.S. Department of Agriculture Forest Service (USFS), an inter-agency Transportation Assistance Group (TAG) site review of the status of planning and the options for providing alternative transportation at the El Yunque National...

  1. Future Forests Webinar Series, Webinar Proceedings and Summary: Ongoing Research and Management Responses to the Mountain Pine Beetle Outbreak

    Treesearch

    M. Matonis; R. Hubbard; K. Gebert; B. Hahn; C. Regan

    2014-01-01

    The Future Forest Webinar Series facilitated dialogue between scientists and managers about the challenges and opportunities created by the mountain pine beetle (MPB) epidemic. The series consisted of six webinar facilitated by the USFS Rocky Mountain Research Station, the Northern and Rocky Mountain Regions, and the Colorado Forest Restoration Institute. The series...

  2. Beach and Morphology Change Using Lidar

    DTIC Science & Technology

    2016-11-01

    Kelly R. Legault PURPOSE: This Coastal and Hydraulics Engineering Technical Note (CHETN) describes the use of lidar data in conjunction with beach...of Expertise. Beach profile surveys were provided by USACE Jacksonville District (SAJ), University of South Florida (USF), and Coastal Planning...within the limits of this study region include the Pinellas County Shoreline Protection Project (SPP) (USACE SAJ 2010), Tampa Harbor Navigation

  3. An effective assessment protocol for continuous geospatial datasets of forest characteristics using USFS Forest Inventory and Analysis (FIA) data

    Treesearch

    Rachel Riemann; Barry Tyler Wilson; Andrew Lister; Sarah Parks

    2010-01-01

    Geospatial datasets of forest characteristics are modeled representations of real populations on the ground. The continuous spatial character of such datasets provides an incredible source of information at the landscape level for ecosystem research, policy analysis, and planning applications, all of which are critical for addressing current challenges related to...

  4. Fort Valley Experimental Forest-A Century of Research 1908-2008

    Treesearch

    Susan D. Olberding; Margaret M. Moore

    2008-01-01

    One hundred years ago, the USFS began its forest research program in a two-room cabin near Flagstaff, Arizona, with one staff person, Gustaf A. Pearson. The site became known as the Fort Valley Experiment Station and was the first in a national network of research sites developed to address uncertainties regarding the rehabilitation and conservation for forest and...

  5. Fort Valley Experimental Forest-A Century of Research 1908-2008 (P-53)

    Treesearch

    Susan D. Olberding; Margaret M. Moore

    2008-01-01

    One hundred years ago, the USFS began its forest research program in a two-room cabin near Flagstaff, Arizona, with one staff person, Gustaf A. Pearson. The site became known as the Fort Valley Experiment Station and was the first in a national network of research sites developed to address uncertainties regarding the rehabilitation and conservation for forest and...

  6. Effects of climate change on ecosystem services in the Northern Rockies Region [Chapter 11

    Treesearch

    Travis Warziniack; Megan Lawson; S. Karen Dante-Wood

    2018-01-01

    In this chapter, we focus on the ecosystem services provided to people who visit, live adjacent to, or otherwise benefit from natural resources on public lands. Communities in the Forest Service, U.S. Department of Agriculture (USFS) Northern Region and the Greater Yellowstone Area (GYA), hereafter called the Northern Rockies region, are highly dependent on ecosystem...

  7. The North Fork of Caspar Creek: a cooperative venture between CDF and USFS

    Treesearch

    Pete Cafferata

    1984-01-01

    The Caspar Creek Watershed Study on JDSF has taken a new direction in the last two years, as our work progresses towards full instrumentation of the North Fork phase. When most of the equipment has been installed by the end of the summer, this 1195-acre watershed will become the most intensively sampled drainage ever studied by hydrologists.

  8. Releases of natural enemies in Hawaii since 1980 for classical biological control of weeds

    Treesearch

    P. Conant; J. N. Garcia; M. T. Johnson; W. T. Nagamine; C. K. Hirayama; G. P. Markin; R. L. Hill

    2013-01-01

    A comprehensive review of biological control of weeds in Hawaii was last published in 1992, covering 74 natural enemy species released from 1902 through 1980. The present review summarizes releases of 21 natural enemies targeting seven invasive weeds from 1981 to 2010. These projects were carried out by Hawaii Department of Agriculture (HDOA), USDA Forest Service (USFS...

  9. Pennsylvania's experiences with microbial control of the gypsy moth

    Treesearch

    James O. Nichols

    1985-01-01

    Pennsylvania's first experience with using Bt on insect control occurred in 1964. For the next 17 years, various projects were conducted, in cooperation with the USFS and industry, in an effort to secure operational status of Bt for gypsy moth suppression. This point was reached in 1982, and the Governor was convinced that the time was right to convert most gypsy...

  10. Designing economic impact assessments for USFS wildfire programs

    Treesearch

    Karen L. Abt; Robert J. Jr. Huggett; Thomas P. Holmes

    2008-01-01

    As often happens in the wake of a series of extreme fire seasons, such as those in 2000, 2002 and 2003, federal wildfire policy is being scrutinized and recommendations regarding changes both large and small are prevalent (Stephens and Ruth 2005, Busenberg 2004, Dellasalla et al. 2004, Dombeck et al. 2004). It is common practice for increases in acres burned and in...

  11. A century of cooperation: The Fort Valley Experimental Forest and the Coconino National Forest in Flagstaff

    Treesearch

    Susan D. Olberding; Karen Malis-Clark; Peter J. Pilles; Dennis Lund

    2008-01-01

    This poster presents the continuing cooperative relationship between the Fort Valley Experimental Forest (FVEF), Coconino National Forest (CNF), USFS Region 3, and the long-term partnerships with the Museum of the Northern Arizona and the NAU School of Forestry.Fort Valley was initially named the Coconino Experiment Station and funds were channeled...

  12. A century of cooperation: The Fort Valley Experimental Forest and the Coconino National Forest in Flagstaff (P-53)

    Treesearch

    Susan D. Olberding; Karen Malis-Clark; Peter J. Pilles; Dennis Lund

    2008-01-01

    This poster presents the continuing cooperative relationship between the Fort Valley Experimental Forest (FVEF), Coconino National Forest (CNF), USFS Region 3, and the long-term partnerships with the Museum of the Northern Arizona and the NAU School of Forestry. Fort Valley was initially named the Coconino Experiment Station and funds were channeled...

  13. A Search for TRUTH in Student Responses to Selected Survey Items. AIR 1993 Annual Forum Paper.

    ERIC Educational Resources Information Center

    Takalkar, Pradnya; And Others

    This study compared 4,594 student responses from three different surveys of incoming students at the University of South Florida (USF) with data from Florida's State University System (SUS) admissions files to determine what proportion of error occurs in the survey responses. Specifically, the study investigated the amount of measurement error in…

  14. Focusing on Success: Examples of How the Universal Service Fund Is Helping Schools and Libraries around the Country

    ERIC Educational Resources Information Center

    Universal Service Administrative Company, 2007

    2007-01-01

    This report shows how Universal Service Fund support for schools and libraries is used by school districts and libraries around the country. Highlighted are approximately 190 success stories of program participants that have come to rely on the USF to expand educational opportunities for students through better use of telecommunications technology…

  15. A tool to analyze environmental impacts of roads on forest watersheds

    Treesearch

    Ajay Prasad

    2007-01-01

    The construction and use of forest roads can have impacts on geomorphic processes and erosion patterns in forested basins. Analyzing these impacts will help forest managers to effectively manage road and road drainage system and hence minimize the negative impacts of forest roads. To manage forest roads effectively the USDA Forest Service (USFS) has developed a road...

  16. Sensitivity of Landsat image-derived burn severity indices to immediate post-fire effects

    Treesearch

    A. T. Hudak; S. Lewis; P. Robichaud; P. Morgan; M. Bobbitt; L. Lentile; A. Smith; Z. Holden; J. Clark; R. McKinley

    2006-01-01

    The USFS Remote Sensing Applications Center (RSAC) and the USGS Center for Earth Resources Observation and Science (EROS) produce Burned Area Reflectance Classification (BARC) maps as a rapid, preliminary indication of burn severity on large wildfire events. Currently the preferred burn severity index is the delta Normalized Burn Ratio (dNBR), which requires NBR values...

  17. Characterizing large airtanker use in United States fire management

    Treesearch

    Crystal S. Stonesifer; Matthew P. Thompson; Dave Calkin; Charles W. McHugh

    2015-01-01

    The appropriate role of large airtankers (LATs) in federal fire suppression in the United States has been the source of much debate and discussion in recent years as the U.S. Forest Service (USFS) has faced impending decisions about how best to address an aging fleet of contracted aircraft. Questions of fleet efficiency are complicated by inadequacies in historical...

  18. Historic and Contemporary Land Use in Southwestern Grassland Ecosystems

    Treesearch

    Carol Raish

    2004-01-01

    This chapter encompasses the lands of the Southwest as defined by Region 3 of the USDA Forest Service (USFS): Arizona, New Mexico, and portions of western Oklahoma and the Texas Panhandle. I examine human use and modification of the grasslands/rangelands of this region, with an emphasis on those areas managed by the Forest Service. Because the majority of publications...

  19. Forest Inventory and Analysis National Data Quality Assessment Report for 2000 to 2003

    Treesearch

    James E. Pollard; James A. Westfall; Paul L. Patterson; David L. Gartner; Mark Hansen; Olaf Kuegler

    2006-01-01

    The Forest Inventory and Analysis program (FIA) is the key USDA Forest Service (USFS) program that provides the information needed to assess the status and trends in the environmental quality of the Nation's forests. The goal of the FIA Quality Assurance (QA) program is to provide a framework to assure the production of complete, accurate and unbiased forest...

  20. Forest and range research on the "Wild Bill Plots" (1927-2007)

    Treesearch

    Daniel C. Laughlin; Margaret M. Moore

    2008-01-01

    In 1927, the Fort Valley Experimental Forest initiated a range-timber reproduction study. The study was one of the first attempts to experimentally isolate the agents responsible for injury to ponderosa pine regeneration, and at the same time assess the impacts of livestock grazing on herbaceous vegetation. The study was conducted on the USFS range allotments northwest...

  1. Forest and range research on the "Wild Bill Plots" (1927-2007) (P-53)

    Treesearch

    Daniel C. Laughlin; Margaret M. Moore

    2008-01-01

    In 1927, the Fort Valley Experimental Forest initiated a range-timber reproduction study. The study was one of the first attempts to experimentally isolate the agents responsible for injury to ponderosa pine regeneration, and at the same time assess the impacts of livestock grazing on herbaceous vegetation. The study was conducted on the USFS range allotments northwest...

  2. CTUIR Grande Ronde River Basin Watershed Restoration Program McCoy Creek/McIntyre Creek Road Crossing, 1996-1998 Progress Report.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Childs, Allen B.

    1999-07-01

    This Annual Report provides a detailed overview of watershed restoration accomplishments achieved by the Confederated Tribes of the Umatilla Indian Reservation (CTUIR) and project partners in the Upper Grande Ronde River Basin under contract with the Bonneville Power Administration (BPA) during the period July 1, 1997 through June 30, 1998. The Contract Agreement entitled McCoy Meadows Watershed Restoration Project (Project No.96-83-01) includes habitat restoration planning, design, and implementation in two project areas--the McCoy Meadows Ranch located in the Meadow, McCoy, and McIntyre Creek subbasins on private land and the Mainstem Grande Ronde River Habitat Enhancement Project located on private andmore » National Forest System lands near Bird Tract Springs along the Grande Ronde River. During the contract period, the CTUIR and partners (Mark and Lorna Tipperman, landowners), Oregon Department of Environmental Quality (ODEQ), U.S. Environmental Protection Agency (EPA), Oregon Department of Fish and Wildlife (ODFW), and Natural Resource Conservation Service (NRCS) initiated phase 1 construction of the McCoy Meadows Restoration Project. Phase 1 involved reintroduction of a segment of McCoy Creek from its existing channelized configuration into a historic meander channel. Project efforts included bioengineering and tree/shrub planting and protection, transporting salvaged cottonwood tree boles and limbs from offsite source to the project area for utilization by resident beaver populations for forage and dam construction materials, relocation of existing BPA/ODFW riparian corridor fencing to outer edges of meadow floodplain, establishment of pre-project photo points, and coordination of other monitoring and evaluation efforts being led by other project partners including groundwater monitoring wells, channel cross sections, water quality monitoring stations, juvenile population sampling index sites, redd surveys, and habitat surveys. Project activities also included coordination with the U.S. Forest Service, Wallowa-Whitman National Forest, LaGrande Ranger District (USFS) on the Forest Road 2137 (McIntyre Road) Relocation and Obliteration Project and the McCoy Creek crossing. The USFS completed engineering designs under the cooperative effort for the McCoy Creek crossing. Project activities accomplished on the Upper Mainstem Large Wood Addition Project included placement of approximately 120 whole trees to enhance instream structural diversity, pool habitat quality, streambank stability, and improved floodplain morphology. Project activities accomplished on the Mainstem Grande Ronde Habitat Enhancement Project included coordination with landowners (Shauna Musgrove of Cuhna Ranches, Dean Stone, and the Wallowa-Whitman National Forest, LaGrande Ranger District) to develop a habitat enhancement/restoration project opportunity along a 3 mile section of the mainstem Grande Ronde River and major tributaries including the lower reaches of Bear Creek and Jordan Creek. Upon securing an agreement with the landowners, project partners including the CTUIR, ODFW, NRCS, and USFS initiated development of project objectives and site-specific designs. By June 1998, project designs were completed and preparations nearly complete to initiate onsite project construction.« less

  3. U.S. Forest Service Research and Development (USFS R/D) national science strategy on White Nose Syndrome (WNS)

    Treesearch

    Sybill Amelon; Robert T. Brooks; Jessie Glaeser; Megan Friggens; Daniel Lindner; Susan C. Loeb; Ann Lynch; Drew Minnis; Roger Perry; Mary M. Rowland; Monica Tomosy; Ted Weller

    2012-01-01

    The National Plan for Assisting States, Federal Agencies, and Tribes in Managing White-Nose Syndrome in Bats (National WNS Plan), is a document prepared jointly by the U.S. Departments of the Interior, Agriculture, and Defense, along with the Association of Fish and Wildlife Agencies. This document provides a strategic framework for the investigation and management of...

  4. 75 FR 56979 - Central Electric Power Cooperative, Inc.: Notice of Intent To Hold a Public Scoping Meeting and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-17

    ... issue a special use permit for the proposal. RUS is the lead agency conducting the EIS, and the USFS... refined as part of the EIS scoping process and will be addressed in the EIS. Public health and safety, environmental impacts, and engineering aspects of the proposal will be considered in the EIS. RUS is the lead...

  5. Assessment of soil disturbance in forests of the interior Columbia River basin: a critique

    Treesearch

    Richard E. Miller; James D. McIver; Steven W. Howes; William B. Gaeuman

    2010-01-01

    We present results and inferences from 15 soil-monitoring projects by the USDA Forest Service (USFS) after logging in the interior Columbia River basin. Details and comments about each project are provided in separate appendixes. In general, application of past protocols overestimated the percentage of “detrimentally” disturbed soil in harvested units. Based on this...

  6. Universal Service Fund: Background and Options for Reform

    DTIC Science & Technology

    2010-03-11

    pursues violators and initiates enforcement actions including notices of liability, suspensions , consent decrees, and debarments .46 The Department...series of measures to safeguard the USF to deter fraud, waste, and abuse. Included in the measures taken are those that extend the debarment rules...three years) and sanctions for criminal and civil violations beyond the Schools and Libraries Program to cover all four programs; tighten rules

  7. Effects of Climate Change on Cultural Resources in the Northern Rockies Region [Chapter 12

    Treesearch

    Carl M. Davis

    2018-01-01

    People have inhabited the Northern Rocky Mountains of the United States since the close of the last Pleistocene glacial period, some 14,000 years B.P. (Fagan 1990; Meltzer 2009). Evidence of this ancient and more recent human occupation is found throughout the Forest Service, U.S. Department of Agriculture (USFS) Northern Region and the Greater Yellowstone Area,...

  8. Integrating ecosystem services into national Forest Service policy and operations

    Treesearch

    Robert Deal; Lisa Fong; Erin Phelps; Emily Weidner; Jonas Epstein; Tommie Herbert; Mary Snieckus; Nikola Smith; Tania Ellersick; Greg Arthaud

    2017-01-01

    The ecosystem services concept describes the many benefits people receive from nature. It highlights the importance of managing public and private lands sustainably to ensure these benefits continue into the future, and it closely aligns with the U.S. Forest Service (USFS) mission to “sustain the health, diversity, and productivity of the Nation’s forests and...

  9. Welcome - TampaBay.WaterAtlas.org

    Science.gov Websites

    An edition of: WaterAtlas.orgPresented By: USF Water Institute Choose a Water Atlas Charlotte Harbor NEP Water Atlas Hillsborough County Water Atlas Lake County Water Atlas Manatee County Water Atlas Orange County Water Atlas Pinellas County Water Atlas Polk County Water Atlas Sarasota County Water Atlas

  10. The development of landscape-scale ecological units and their application to the greater Huachuca Mountains fire planning process

    Treesearch

    Larry E. Laing; David Gori; James T. Jones

    2005-01-01

    The multi-partner Greater Huachuca Mountains fire planning effort involves over 500,000 acres of public and private lands. This large area supports distinct landscapes that have evolved with fire. Utilizing GIS as a tool, the United States Forest Service (USFS), General Ecosystem Survey (GES), and Natural Resources Conservation Service (NRCS) State Soil Geographic...

  11. Carbon stocks on forestland of the United States, with emphasis on USDA Forest Service ownership

    Treesearch

    Linda S. Heath; James E. Smith; Christopher W. Woodall; David L. Azuma; Karen L. Waddell

    2011-01-01

    The U.S. Department of Agriculture Forest Service (USFS) manages one-fifth of the area of forestland in the United States. The Forest Service Roadmap for responding to climate change identified assessing and managing carbon stocks and change as a major element of its plan. This study presents methods and results of estimating current forest carbon stocks and change in...

  12. Involving the public in restoring the role of fire in the longleaf pine ecosystem of Upland Island Wilderness

    Treesearch

    Brian P. Oswald; Ike McWhorter; Penny. Whisenant

    2011-01-01

    The 13,250-acre Upland Island Wilderness (UIW) in Texas was established in 1984 and is managed by the United States Forest Service (USFS). Historically, portions of it consisted of open and diverse longleaf pine (Pinus palustris) ecosystems which depend on frequent, low-intensity surface fires. As in many other relatively small wilderness areas, the...

  13. Carbon stocks on forestland of the United States, with emphaisis on USDA Forest Service ownership

    Treesearch

    Linda S. Heath; James E. Smith; Christopher W. Woodall; Dave Azuma; Karen L. Waddell

    2011-01-01

    The U.S. Department of Agriculture Forest Service (USFS) manages one-fifth of the area of forestland in the United States. The Forest Service Roadmap for responding to climate change identified assessing and managing carbon stocks and change as a major element of its plan. This study presents methods and results of estimating current forest carbon stocks and change in...

  14. The Fundamental Chemistry and Physics of Munitions under Extreme Conditions

    DTIC Science & Technology

    2011-02-01

    I. I. Oleynik, S. V. Zybin, and C. T. White, “Density Functional Theory Calculations of Solid Nitromethane under Hydrostatic and Uniaxial...White (NRL), Ivan Oleynik (USF): anisotropic nonlinear elasticity and equations of states of crystalline EM (PETN, RDX, HMX, TATB, nitromethane ...and nitromethane ;  Aidan Thompson (SNL): shock-to-detonation transition in PETN and CL-20;  Ronnie Kosloff (Hebrew University of Jerusalem

  15. Mission Command: Retooling the Leadership Paradigm for Homeland Security Crisis Response?

    DTIC Science & Technology

    2015-03-01

    security crisis management. While, there is some literature regarding the efforts by the USFS and the federal wildland firefighting community towards...psychologically stressful and potentially overwhelming. The need to communicate and cooperate with other agencies in a crisis places added...environment where formal hierarchies and tightly controlled plans may become irrelevant in a crisis . Grant and De Waard examined the communication

  16. Mapping timing, extent, type and magnitude of disturbances across the national forest system, 1990–2011

    Treesearch

    Alexander Hernandez; Sean P. Healey; Chenquan Huang; R. Douglas Ramsey

    2015-01-01

    As part of the U.S. Forest Service (USFS), National Forest System (NFS) comprehensive plan for carbon monitoring, a detailed temporal mapping of forest disturbances across all National Forests in the United States has been conducted. A long-term annual time series of data layers that show the timing, extent, type, and magnitude of disturbance beginning in 1990 and...

  17. Nonpoint Source Discharge Control on Non-Builtup Military Lands: Compliance Background Analysis Through October 1999

    DTIC Science & Technology

    2000-08-01

    management for NPS. The State nonpoint Source Task Force coordinates joint watershed management efforts with SCS, USFS, BLM. Intense grazing and...nonpoint source water pollution discharges from unimproved lands, particularly military lands. Increasing emphasis at national and state levels on...lands, particularly military lands. Increasing emphasis at national and state levels on controlling pollutant discharges from nonpoint sources and

  18. An Attempt to Identify Comparatively Supportive and Non-Supportive Environments for Underrepresented Minorities and Females in SUS Colleges of Engineering

    ERIC Educational Resources Information Center

    Micceri, Theodore

    2005-01-01

    This study sought to determine whether consistent differences in enrollment and graduation among different racial/ethnic and sex groups occur at different colleges of Engineering in the Florida State University System (SUS). Analyses were limited to the major institutions (UF, FSU, USF, UCF, FAU, FIU) with the addition of FAMU due to a high…

  19. How useful is LiDAR in establishing a stream gauging network in a tropical experimental forest

    Treesearch

    Boris Poff; Daniel G. Neary; Gregory P. Asner

    2008-01-01

    In the late summer of 2007 the Institute for Pacific Islands Forestry (IPIF), which is part of the US Forest Service Pacific Southwestern Research Station, asked the USFS Rocky Mountain Research Station's (RMRS) Air, Water and Aquatic Program's (AWA) Southwest Watershed Science Team for assistance in the establishing baseline data in the initial phase of a...

  20. Transportation Observations, Considerations, and Recommendations relative to the Colorado Front Range Provided by the Interagency Transportation Assistance Group (TAG) / Alternative Transportation in Parks and Public Lands (ATPPL) Program, Lakewood, CO, J

    DOT National Transportation Integrated Search

    2007-07-24

    A review of the transportation in the Front Range region of Colorado by the inter-agency : Transportation Assistance Group (TAG) was conducted July 24-26, 2007, on behalf of : the U.S. Department of Agriculture Forest Service (USFS) in cooperation wi...

  1. Clarifying details on a 1930s-era pine-hardwood stand in Arkansas

    Treesearch

    Don C.  Bragg

    2015-01-01

    Data from recently discovered daily-work logs of US Forest Service (USFS) researcher Russell R. Reynolds enabled me to clarify a study I published a decade ago on a 1930s-vintage unmanaged, second-growth Pinus (pine)–hardwood stand in southeastern Arkansas. Though still too vague to reveal every detail, Reynolds’ work logs confirmed a number of...

  2. Estimates of carbon stored in harvested wood products from the United States Forest Service Northern Region, 1906-2010

    Treesearch

    Keith D. Stockmann; Nathaniel M. Anderson; Kenneth E. Skog; Sean P. Healey; Dan R. Loeffler; Greg Jones; James F. Morrison

    2012-01-01

    Global forests capture and store significant amounts of CO2 through photosynthesis. When carbon is removed from forests through harvest, a portion of the harvested carbon is stored in wood products, often for many decades. The United States Forest Service (USFS) and other agencies are interested in accurately accounting for carbon flux associated with harvested wood...

  3. Estimates of carbon stored in harvested wood products from United States Forest Service Rocky Mountain Region, 1906-2012

    Treesearch

    Keith Stockmann; Nathaniel Anderson; Jesse Young; Ken Skog; Sean Healey; Dan Loeffler; Edward Butler; J. Greg Jones; James Morrison

    2014-01-01

    Global forests capture and store significant amounts of carbon through photosynthesis. When carbon is removed from forests through harvest, a portion of the harvested carbon is stored in wood products, often for many decades. The United States Forest Service (USFS) and other agencies are interested in accurately accounting for carbon flux associated with harvested wood...

  4. Estimates of carbon stored in harvested wood products from United States Forest Service Pacific Northwest Region, 1909-2012

    Treesearch

    Edward Butler; Keith Stockmann; Nathaniel Anderson; Ken Skog; Sean Healey; Dan Loeffler; J. Greg Jones; James Morrison; Jesse Young

    2014-01-01

    Global forests capture and store significant amounts of carbon through photosynthesis. When carbon is removed from forests through harvest, a portion of the harvested carbon is stored in wood products, often for many decades. The United States Forest Service (USFS) and other agencies are interested in accurately accounting for carbon flux associated with harvested wood...

  5. Estimates of carbon stored in harvested wood products from United States Forest Service Northern Region, 1906-2012

    Treesearch

    Keith Stockmann; Nathaniel Anderson; Jesse Young; Ken Skog; Sean Healey; Dan Loeffler; Edward Butler; J. Greg Jones; James Morrison

    2014-01-01

    Global forests capture and store significant amounts of carbon through photosynthesis. When carbon is removed from forests through harvest, a portion of the harvested carbon is stored in wood products, often for many decades. The United States Forest Service (USFS) and other agencies are interested in accurately accounting for carbon flux associated with harvested wood...

  6. Estimates of carbon stored in harvested wood products from United States Forest Service Eastern Region, 1911-2012

    Treesearch

    Dan Loeffler; Nathaniel Anderson; Keith Stockmann; Ken Skog; Sean Healey; J. Greg Jones; James Morrison; Jesse Young

    2014-01-01

    Global forests capture and store significant amounts of carbon through photosynthesis. When carbon is removed from forests through harvest, a portion of the harvested carbon is stored in wood products, often for many decades. The United States Forest Service (USFS) and other agencies are interested in accurately accounting for carbon flux associated with harvested wood...

  7. Estimates of carbon stored in harvested wood products from United States Forest Service Intermountain Region, 1911-2012

    Treesearch

    Keith Stockmann; Nathaniel Anderson; Jesse Young; Ken Skog; Sean Healey; Dan Loeffler; Edward Butler; J. Greg Jones; James Morrison

    2014-01-01

    Global forests capture and store significant amounts of carbon through photosynthesis. When carbon is removed from forests through harvest, a portion of the harvested carbon is stored in wood products, often for many decades. The United States Forest Service (USFS) and other agencies are interested in accurately accounting for carbon flux associated with harvested wood...

  8. Environmental accounting of natural capital and ecosystem services for the US National Forest System

    Treesearch

    Elliot T. Campbell; Mark T. Brown; NO-VALUE

    2012-01-01

    The National Forests of the United States encompass 192.7 million acres (78 million hectares) of land, which is nearly five percent of the total land area of the nation. These lands are managed by the US Forest Service (USFS) for multiple uses, including extraction of timber, production of fossil fuels and minerals, public recreation, and the preservation of...

  9. Estimates of carbon stored in harvested wood products from United States Forest Service Alaska Region, 1910-2012

    Treesearch

    Dan Loeffler; Nathaniel Anderson; Keith Stockmann; Ken Skog; Sean Healey; J. Greg Jones; James Morrison; Jesse Young

    2014-01-01

    Global forests capture and store significant amounts of carbon through photosynthesis. When carbon is removed from forests through harvest, a portion of the harvested carbon is stored in wood products, often for many decades. The United States Forest Service (USFS) and other agencies are interested in accurately accounting for carbon flux associated with harvested wood...

  10. Estimates of carbon stored in harvested wood products from United States Forest Service Pacific Southwest Region, 1909-2012

    Treesearch

    Keith Stockmann; Nathaniel Anderson; Jesse Young; Ken Skog; Sean Healey; Dan Loeffler; Edward Butler; J. Greg Jones; James Morrison

    2014-01-01

    Global forests capture and store significant amounts of carbon through photosynthesis. When carbon is removed from forests through harvest, a portion of the harvested carbon is stored in wood products, often for many decades. The United States Forest Service (USFS) and other agencies are interested in accurately accounting for carbon flux associated with harvested wood...

  11. Estimates of carbon stored in harvested wood products from United States Forest Service Southwestern Region, 1909-2012

    Treesearch

    Edward Butler; Keith Stockmann; Nathaniel Anderson; Jesse Young; Ken Skog; Sean Healey; Dan Loeffler; J. Greg Jones; James Morrison

    2014-01-01

    Global forests capture and store significant amounts of carbon through photosynthesis. When carbon is removed from forests through harvest, a portion of the harvested carbon is stored in wood products, often for many decades. The United States Forest Service (USFS) and other agencies are interested in accurately accounting for carbon flux associated with harvested wood...

  12. Estimates of carbon stored in harvested wood products from United States Forest Service Southern Region, 1911-2012

    Treesearch

    Dan Loeffler; Nathaniel Anderson; Keith Stockmann; Ken Skog; Sean Healey; J. Greg Jones; James Morrison; Jesse Young

    2014-01-01

    Global forests capture and store significant amounts of carbon through photosynthesis. When carbon is removed from forests through harvest, a portion of the harvested carbon is stored in wood products, often for many decades. The United States Forest Service (USFS) and other agencies are interested in accurately accounting for carbon flux associated with harvested wood...

  13. Lake and bulk sampling chemistry, NADP, and IMPROVE air quality data analysis on the Bridger-Teton National Forest (USFS Region 4)

    Treesearch

    Jill Grenon; Terry Svalberg; Ted Porwoll; Mark Story

    2010-01-01

    Air quality monitoring data from several programs in and around the Bridger-Teton (B-T) National Forest - National Atmospheric Deposition Program (NADP), longterm lake monitoring, long-term bulk precipitation monitoring (both snow and rain), and Interagency Monitoring of Protected Visual Environments (IMPROVE) - were analyzed in this report. Trends were analyzed using...

  14. Radiotelemetry Tracking at Lake Conway, Florida.

    DTIC Science & Technology

    1982-08-01

    USF) initiated a study to evaluate the impact of the introduced white amur on the resident herpetofaunal community . A major part of this effort was...initiated a study to determine the impact of the introduced white amur on the resident herpetofaunal community (Godley, in preparation). A major part of...42. Analysis of the project funding schedule indicated that herpetofaunal radiotagging would be economically feasible only if the existing mobile

  15. Preliminary results from a survey of U.S. Forest Service wildfire managers' attitudes toward aviation personnel exposure and risk

    Treesearch

    Matthew Wibbenmeyer; Michael Hand; David Calkin

    2012-01-01

    The U.S. Department of Agriculture, Forest Service (USFS) has, in recent years, increasingly emphasized the importance of safety to its employees, but wildfire management remains a risky endeavor. While wildfire management decisions affecting safety and exposure of firefighters to the wildland fire environment may be aided by decision support tools such the Wildfire...

  16. An Intercomparison of Large-Extent Tree Canopy Cover Geospatial Datasets

    NASA Astrophysics Data System (ADS)

    Bender, S.; Liknes, G.; Ruefenacht, B.; Reynolds, J.; Miller, W. P.

    2017-12-01

    As a member of the Multi-Resolution Land Characteristics Consortium (MRLC), the U.S. Forest Service (USFS) is responsible for producing and maintaining the tree canopy cover (TCC) component of the National Land Cover Database (NLCD). The NLCD-TCC data are available for the conterminous United States (CONUS), coastal Alaska, Hawai'i, Puerto Rico, and the U.S. Virgin Islands. The most recent official version of the NLCD-TCC data is based primarily on reference data from 2010-2011 and is part of the multi-component 2011 version of the NLCD. NLCD data are updated on a five-year cycle. The USFS is currently producing the next official version (2016) of the NLCD-TCC data for the United States, and it will be made publicly-available in early 2018. In this presentation, we describe the model inputs, modeling methods, and tools used to produce the 30-m NLCD-TCC data. Several tree cover datasets at 30-m, as well as datasets at finer resolution, have become available in recent years due to advancements in earth observation data and their availability, computing, and sensors. We compare multiple tree cover datasets that have similar resolution to the NLCD-TCC data. We also aggregate the tree class from fine-resolution land cover datasets to a percent canopy value on a 30-m pixel, in order to compare the fine-resolution datasets to the datasets created directly from 30-m Landsat data. The extent of the tree canopy cover datasets included in the study ranges from global and national to the state level. Preliminary investigation of multiple tree cover datasets over the CONUS indicates a high amount of spatial variability. For example, in a comparison of the NLCD-TCC and the Global Land Cover Facility's Landsat Tree Cover Continuous Fields (2010) data by MRLC mapping zones, the zone-level root mean-square deviation ranges from 2% to 39% (mean=17%, median=15%). The analysis outcomes are expected to inform USFS decisions with regard to the next cycle (2021) of NLCD-TCC production.

  17. Relative impact of previous disturbance history on the likelihood of additional disturbance in the Northern United States Forest Service USFS Region

    NASA Astrophysics Data System (ADS)

    Hernandez, A. J.

    2015-12-01

    The Landsat archive is increasingly being used to detect trends in the occurrence of forest disturbance. Beyond information about the amount of area affected, forest managers need to know if and how disturbance regimes change. The National Forest System (NFS) has developed a comprehensive plan for carbon monitoring that requires a detailed temporal mapping of forest disturbances across 75 million hectares. A long-term annual time series that shows the timing, extent, and type of disturbance beginning in 1990 and ending in 2011 has been prepared for several USFS Regions, including the Northern Region. Our mapping starts with an automated detection of annual disturbances using a time series of historical Landsat imagery. Automated detections are meticulously inspected, corrected and labeled using various USFS ancillary datasets. The resulting maps of verified disturbance show the timing and types are fires, harvests, insect activity, disease, and abiotic (wind, drought, avalanche) damage. Also, the magnitude of each change event is modeled in terms of the proportion of canopy cover lost. The sequence of disturbances for every pixel since 1990 has been consistently mapped and is available across the entirety of NFS. Our datasets contain sufficient information to describe the frequency of stand replacement, as well as how often disturbance results in only a partial loss of canopy. This information provides empirical insight into how an initial disturbance may predispose a stand to further disturbance, and it also show a climatic signal in the occurrence of processes such as fire and insect epidemics. Thus, we have the information to model the likelihood of occurrence of certain disturbances after a given event (i.e. if we have a fire in the past what does that do to the likelihood of occurrence of insects in the future). Here, we explore if previous disturbance history is a reliable predictor of additional disturbance in the future and we present results of applying logistic regression to obtain predicted probabilities of occurrence of additional disturbance types. We describe responses in additional disturbance and prominent trends for each major forest type.

  18. Empirical Succession Mapping and Data Assimilation to Constrain Demographic Processes in an Ecosystem Model

    NASA Astrophysics Data System (ADS)

    Kelly, R.; Andrews, T.; Dietze, M.

    2015-12-01

    Shifts in ecological communities in response to environmental change have implications for biodiversity, ecosystem function, and feedbacks to global climate change. Community composition is fundamentally the product of demography, but demographic processes are simplified or missing altogether in many ecosystem, Earth system, and species distribution models. This limitation arises in part because demographic data are noisy and difficult to synthesize. As a consequence, demographic processes are challenging to formulate in models in the first place, and to verify and constrain with data thereafter. Here, we used a novel analysis of the USFS Forest Inventory Analysis to improve the representation of demography in an ecosystem model. First, we created an Empirical Succession Mapping (ESM) based on ~1 million individual tree observations from the eastern U.S. to identify broad demographic patterns related to forest succession and disturbance. We used results from this analysis to guide reformulation of the Ecosystem Demography model (ED), an existing forest simulator with explicit tree demography. Results from the ESM reveal a coherent, cyclic pattern of change in temperate forest tree size and density over the eastern U.S. The ESM captures key ecological processes including succession, self-thinning, and gap-filling, and quantifies the typical trajectory of these processes as a function of tree size and stand density. Recruitment is most rapid in early-successional stands with low density and mean diameter, but slows as stand density increases; mean diameter increases until thinning promotes recruitment of small-diameter trees. Strikingly, the upper bound of size-density space that emerges in the ESM conforms closely to the self-thinning power law often observed in ecology. The ED model obeys this same overall size-density boundary, but overestimates plot-level growth, mortality, and fecundity rates, leading to unrealistic emergent demographic patterns. In particular, the current ED formulation cannot capture steady state dynamics evident in the ESM. Ongoing efforts are aimed at reformulating ED to more closely approach overall forest dynamics evident in the ESM, and then assimilating inventory data to constrain model parameters and initial conditions.

  19. Quantifying multi-dimensional functional trait spaces of trees: empirical versus theoretical approaches

    NASA Astrophysics Data System (ADS)

    Ogle, K.; Fell, M.; Barber, J. J.

    2016-12-01

    Empirical, field studies of plant functional traits have revealed important trade-offs among pairs or triplets of traits, such as the leaf (LES) and wood (WES) economics spectra. Trade-offs include correlations between leaf longevity (LL) vs specific leaf area (SLA), LL vs mass-specific leaf respiration rate (RmL), SLA vs RmL, and resistance to breakage vs wood density. Ordination analyses (e.g., PCA) show groupings of traits that tend to align with different life-history strategies or taxonomic groups. It is unclear, however, what underlies such trade-offs and emergent spectra. Do they arise from inherent physiological constraints on growth, or are they more reflective of environmental filtering? The relative importance of these mechanisms has implications for predicting biogeochemical cycling, which is influenced by trait distributions of the plant community. We address this question using an individual-based model of tree growth (ACGCA) to quantify the theoretical trait space of trees that emerges from physiological constraints. ACGCA's inputs include 32 physiological, anatomical, and allometric traits, many of which are related to the LES and WES. We fit ACGCA to 1.6 million USFS FIA observations of tree diameters and heights to obtain vectors of trait values that produce realistic growth, and we explored the structure of this trait space. No notable correlations emerged among the 496 trait pairs, but stepwise regressions revealed complicated multi-variate structure: e.g., relationships between pairs of traits (e.g., RmL and SLA) are governed by other traits (e.g., LL, radiation-use efficiency [RUE]). We also simulated growth under various canopy gap scenarios that impose varying degrees of environmental filtering to explore the multi-dimensional trait space (hypervolume) of trees that died vs survived. The centroid and volume of the hypervolumes differed among dead and live trees, especially under gap conditions leading to low mortality. Traits most predictive of tree-level mortality were maximum tree height, RUE, xylem conducting area, and branch turn-over rate. We are using these hypervolumes as priors to an emulator that approximates the ACGCA, which we are fitting to the FIA data to quantify species-specific trait spectra and to explore factors giving rise to species differences.

  20. The use of a behavioral response system in the USF/NASA toxicity screening test method

    NASA Technical Reports Server (NTRS)

    Hilado, C. J.; Cumming, H. J.; Packham, S. C.

    1977-01-01

    Relative toxicity data on the pyrolysis effluents from bisphenol A polycarbonate and wool fabric were obtained, based on visual observations of the behavior of free-moving mice and on an avoidance response behavioral paradigm of restrained rats monitored by an instrumented behavioral system. The initial experiments show an essentially 1:1 correlation between the two systems with regard to first signs of incapacitation, collapse, and death from pyrolysis effluents from polycarbonate. It is hypothesized that similarly good correlations between these two systems might exist for other materials exhibiting predominantly carbon monoxide mechanisms of intoxication. This hypothesis needs to be confirmed, however, by additional experiments. Data with wool fabric exhibited greater variability with both procedures, indicating possibly different mechanisms of intoxication for wool as compared with bisphenol A polycarbonate.

  1. High level activity of the mouse CCAAT/enhancer binding protein (C/EBP alpha) gene promoter involves autoregulation and several ubiquitous transcription factors.

    PubMed Central

    Legraverend, C; Antonson, P; Flodby, P; Xanthopoulos, K G

    1993-01-01

    The promoter region of the mouse CCAAT-Enhancer Binding Protein (C/EBP alpha) gene is capable of directing high levels of expression of reporter constructs in various cell lines, albeit even in cells that do not express their endogenous C/EBP alpha gene. To understand the molecular mechanisms underlying this ubiquitous expression, we have characterized the promoter region of the mouse C/EBP alpha gene by a variety of in vitro and in vivo methods. We show that three sites related in sequence to USF, BTE and C/EBP binding sites and present in promoter region -350/+3, are recognized by proteins from rat liver nuclear extracts. The sequence of the C/EBP alpha promoter that includes the USF binding site is also capable of forming stable complexes with purified Myc+Max heterodimers and mutation of this site drastically reduces transcription of C/EBP alpha promoter luciferase constructs both in liver and non liver cell lines. In addition, we identify three novel protein-binding sites two of which display similarity to NF-1 and a NF kappa B binding sites. The region located between nucleotides -197 and -178 forms several heat-stable complexes with liver nuclear proteins in vitro which are recognized mainly by antibodies specific for C/EBP alpha. Furthermore, transient expression of C/EBP alpha and to a lesser extent C/EBP beta expression vectors, results in transactivation of a cotransfected C/EBP alpha promoter-luciferase reporter construct. These experiments support the notion that the C/EBP alpha gene is regulated by C/EBP alpha but other C/EBP-related proteins may also be involved. Images PMID:8493090

  2. Analysis of Variables to Predict First Year Persistence Using Logistic Regression Analysis at the University of South Florida: Model v2.0

    ERIC Educational Resources Information Center

    Herreid, Charlene H.; Miller, Thomas E.

    2009-01-01

    This article is the fourth in a series of articles describing an attrition prediction and intervention project at the University of South Florida (USF) in Tampa. In this article, the researchers describe the updated version of the prediction model. The original model was developed from a sample of about 900 First Time in College (FTIC) students…

  3. A synthesis of five nationwide studies: perceptions of law enforcement and investigations in the USDA Forest Service

    Treesearch

    Deborah J. Chavez; Joanne F. Tynon

    2009-01-01

    This is the synthesis of a series of studies to evaluate perceptions of U.S. Department of Agriculture Forest Service (USFS) law enforcement and investigations (LEI). Five groups were evaluated: four groups of employees from different positions within LEI, and a group of customers of LEI, the line officers of the National Forest System (NFS). The groups responded to...

  4. Stakeholders' relationships with the USDA Forest Service at the Spruce Knob-Seneca Rocks National Recreation Area, West Virginia

    Treesearch

    Katherine A. Thompson; Chad D. Pierskalla; Steven W. Selin

    2007-01-01

    The Spruce Knob-Seneca Rocks National Recreation Area (NRA) is developing a collaborative management plan. To develop a public involvement strategy, it is necessary to assess the social conditions in the area. The purpose of this study was to determine the relationship local stakeholders in the NRA have with the USDA Forest Service (USFS) with regard to the...

  5. The 2014 tanana inventory pilot: A USFS-NASA partnership to leverage advanced remote sensing technologies for forest inventory

    Treesearch

    Hans-Erik Andersen; Chad Babcock; Robert Pattison; Bruce Cook; Doug Morton; Andrew Finley

    2015-01-01

    Interior Alaska (approx. 112 million forested acres in size) is the last remaining forested area within the United States where the Forest Inventory and Analysis (FIA) program is not currently implemented. A joint NASA-FIA inventory pilot project was carried out in 2014 to increase familiarity with interior Alaska logistics and evaluate the utility of state-of-the-art...

  6. NLCD tree canopy cover (TCC) maps of the contiguous United States and coastal Alaska

    Treesearch

    Robert Benton; Bonnie Ruefenacht; Vicky Johnson; Tanushree Biswas; Craig Baker; Mark Finco; Kevin Megown; John Coulston; Ken Winterberger; Mark Riley

    2015-01-01

    A tree canopy cover (TCC) map is one of three elements in the National Land Cover Database (NLCD) 2011 suite of nationwide geospatial data layers. In 2010, the USDA Forest Service (USFS) committed to creating the TCC layer as a member of the Multi-Resolution Land Cover (MRLC) consortium. A general methodology for creating the TCC layer was reported at the 2012 FIA...

  7. Forest service contributions to the national land cover database (NLCD): Tree Canopy Cover Production

    Treesearch

    Bonnie Ruefenacht; Robert Benton; Vicky Johnson; Tanushree Biswas; Craig Baker; Mark Finco; Kevin Megown; John Coulston; Ken Winterberger; Mark Riley

    2015-01-01

    A tree canopy cover (TCC) layer is one of three elements in the National Land Cover Database (NLCD) 2011 suite of nationwide geospatial data layers. In 2010, the USDA Forest Service (USFS) committed to creating the TCC layer as a member of the Multi-Resolution Land Cover (MRLC) consortium. A general methodology for creating the TCC layer was reported at the 2012 FIA...

  8. Soil Quality as an Indicator of Forest Health: an Overview and Initial Results from the USFS Forest Inventory and Analysis Soil Indicator Program

    Treesearch

    Katherine O' Neill; Michael Amacher; Craig Palmer; Barbara Conkling; Greg C. Liknes

    2003-01-01

    The Montreal Process was formed in 1994 to develop an internationally agreed upon set of criteria and indicators for the conservation and sustainable management of temperate and boreal forests. In response to this effort, the USDA Forest Service Forest Inventory and Analysis (FIA) and Forest Health Monitonhg (FHM) programs implemented a national soil monitoring program...

  9. Learn from the burn: The High Park Fire 5 years later

    Treesearch

    Sue Miller; Charles Rhodes; Pete Robichaud; Sandra Ryan; Jen Kovecses; Carl Chambers; Sara Rathburn; Jared Heath; Stephanie Kampf; Codie Wilson; Dan Brogan; Brad Piehl; Mary Ellen Miller; John Giordanengo; Erin Berryman; Monique Rocca

    2017-01-01

    It has been 5 years since the High Park Fire burned over 85,000 acres in Northern Colorado, causing extensive property damage, loss of life, and severe impacts to the water quality of the Poudre River. In the fall of 2016, a conference was organized by the USFS Rocky Mountain Research Station and the Coalition for the Poudre River Watershed to discuss what has been...

  10. Two for the Price of One: Integration of NEPA and NHPA Procedures

    DTIC Science & Technology

    2013-09-01

    Air Force Base AFI Air Force Instruction AFPD Air Force Policy Directive AR Army Regulation AT/FP Anti-Terrorism/Force Protection BLM Bureau of...Magnuson-Stevens Fishery Conservation and Management Act NASA National Aeronautics and Space Administration NEPA National Environmental Policy Act...example, the US Forest Service (USFS), US Fish and Wildlife Service (FWS), and Bureau of Land Management ( BLM ) have programs which create military

  11. Regional and forest-level estimates of carbon stored in harvested wood products from the United States Forest Service Northern Region, 1906-2010

    Treesearch

    N. Anderson; J. Young; K. Stockmann; K. Skog; S. Healey; D. Loeffler; J.G. Jones; J. Morrison

    2013-01-01

    Global forests capture and store significant amounts of CO2 through photosynthesis. When carbon is removed from forests through harvest, a portion of the harvested carbon is stored in wood products, often for many decades. The United States Forest Service (USFS) and other agencies are interested in accurately accounting for carbon flux associated with harvested wood...

  12. Quest for safer skies: Modeling golden eagles and wind energy to reduce turbine risk

    Treesearch

    Todd Katzner; Tricia Miller; Scott Stoleson

    2014-01-01

    In a patch of sky above Pennsylvania, a golden eagle moves languidly, never flapping but passing quickly as it cruises southward on a cushion of air. It is migrating to its wintering grounds after a season of breeding in Quebec. As part of a team studying eagles on a daily basis—a project supported by the U.S. Forest Service (USFS), West Virginia University,...

  13. Different fire-climate relationships on forested and non-forested landscapes in the Sierra Nevada ecoregion

    USGS Publications Warehouse

    Keeley, Jon E.; Syphard, Alexandra D.

    2015-01-01

    In the California Sierra Nevada region, increased fire activity over the last 50 years has only occurred in the higher-elevation forests on US Forest Service (USFS) lands, and is not characteristic of the lower-elevation grasslands, woodlands and shrublands on state responsibility lands (Cal Fire). Increased fire activity on USFS lands was correlated with warmer and drier springs. Although this is consistent with recent global warming, we found an equally strong relationship between fire activity and climate in the first half of the 20th century. At lower elevations, warmer and drier conditions were not strongly tied to fire activity over the last 90 years, although prior-year precipitation was significant. It is hypothesised that the fire–climate relationship in forests is determined by climatic effects on spring and summer fuel moisture, with hotter and drier springs leading to a longer fire season and more extensive burning. In contrast, future fire activity in the foothills may be more dependent on rainfall patterns and their effect on the herbaceous fuel load. We predict spring and summer warming will have a significant impact on future fire regimes, primarily in higher-elevation forests. Lower elevation ecosystems are likely to be affected as much by global changes that directly involve land-use patterns as by climate change.

  14. Selecting sagebrush seed sources for restoration in a variable climate: ecophysiological variation among genotypes

    USGS Publications Warehouse

    Germino, Matthew J.

    2012-01-01

    Big sagebrush (Artemisia tridentata) communities dominate a large fraction of the United States and provide critical habitat for a number of wildlife species of concern. Loss of big sagebrush due to fire followed by poor restoration success continues to reduce ecological potential of this ecosystem type, particularly in the Great Basin. Choice of appropriate seed sources for restoration efforts is currently unguided due to knowledge gaps on genetic variation and local adaptation as they relate to a changing landscape. We are assessing ecophysiological responses of big sagebrush to climate variation, comparing plants that germinated from ~20 geographically distinct populations of each of the three subspecies of big sagebrush. Seedlings were previously planted into common gardens by US Forest Service collaborators Drs. B. Richardson and N. Shaw, (USFS Rocky Mountain Research Station, Provo, Utah and Boise, Idaho) as part of the Great Basin Native Plant Selection and Increase Project. Seed sources spanned all states in the conterminous Western United States. Germination, establishment, growth and ecophysiological responses are being linked to genomics and foliar palatability. New information is being produced to aid choice of appropriate seed sources by Bureau of Land Management and USFS field offices when they are planning seed acquisitions for emergency post-fire rehabilitation projects while considering climate variability and wildlife needs.

  15. Forest Fire Mapping

    NASA Technical Reports Server (NTRS)

    1990-01-01

    The Fire Logistics Airborne Mapping Equipment (FLAME) system, mounted in a twin-engine and airplane operated by the U.S. Forest Service (USFS) of the U.S. Department of Agriculture (USDA), is an airborne instrument for detecting and pinpointing forest fires that might escape ground detection. The FLAME equipment rack includes the operator interface, a video monitor, the system's control panel and film output. FLAME's fire detection sensor is an infrared line scanner system that identifies fire boundaries. Sensor's information is correlated with the aircraft's position and altitude at the time the infrared imagery is acquired to fix the fire's location on a map. System can be sent to a fire locale anywhere in the U.S. at the request of a regional forester. USFS felt a need for a more advanced system to deliver timely fire information to fire management personnel in the decade of the 1990s. The Jet Propulsion Laboratory (JPL) conducted a study, jointly sponsored by NASA and USDA, on what advanced technologies might be employed to produce an end-to-end thermal infrared fire detection and mapping system. That led to initiation of the Firefly system, currently in development at JPL and targeted for operational service beginning in 1992. Firefly will employ satellite-reference position fixing and provide performance superior to FLAME.

  16. Mapping of forest disturbance magnitudes across the US National Forest System

    NASA Astrophysics Data System (ADS)

    Hernandez, A. J.; Healey, S. P.; Ramsey, R. D.; McGinty, C.; Garrard, C.; Lu, N.; Huang, C.

    2013-12-01

    A precise record in conjunction with ongoing monitoring of carbon pools constitutes essentials inputs for the continuous modernization of an ever- dynamic science such as climate change. This is particularly important in forested ecosystems for which accurate field archives are available and can be used in combination with historic satellite imagery to obtain spatially explicit estimates of several indicators that can be used in the assessment of said carbon pools. Many forest disturbance processes limit storage of carbon in forested ecosystems and thereby reduce those systems' capacity to mitigate changes in the global climate system. A component of the US National Forest System's (NFS) comprehensive plan for carbon monitoring includes accounting for mapped disturbances, such as fires, harvests, and insect activity. A long-term time series of maps that show the timing, extent, type, and magnitude of disturbances going back to 1990 has been prepared for the United States Forest Service (USFS) Northern Region, and is currently under preparation for the rest of the NFS regions covering more than 75 million hectares. Our mapping approach starts with an automated initial detection of annual disturbances using imagery captured within the growing season from the Landsat archive. Through a meticulous process, the initial detections are then visually inspected, manually corrected and labeled using various USFS ancillary datasets and Google Earth high-resolution historic imagery. We prepared multitemporal models of percent canopy cover and live tree carbon (T/ha) that were calibrated with extensive (in excess of 2000 locations) field data from the US Forest Service Forest Inventory and Analysis program (FIA). The models were then applied to all the years of the radiometrically corrected and normalized Landsat time series in order to provide annual spatially explicit estimates of the magnitude of change in terms of these two attributes. Our results provide objective, widely interpretable estimates of per-year disturbance effects across large areas. Different stakeholders (scientists, managers, policymakers) should benefit from this broad survey of disturbance processes affecting US federal forests over the last 20 years.

  17. The Roles of a Visual Literacy Component in Middle School Language Arts Curricula: A Case Study with At-Risk Students and Their Teachers.

    ERIC Educational Resources Information Center

    Kohl, Virginia; Dressler, Becky; Hoback, John

    As a co-author of the GEAR-UP (Gaining Early Awareness and Readiness for Undergraduate Programs) grant proposal to the Department of Education in 1999, the primary author (Kohl) of this paper is in her third year of working at Franklin Middle School, which largely serves at-risk minority students through the University of South Florida (USF),…

  18. A century of avian research on USFS Experimental Forests and Ranges: Introduction to the special section on long-term avian research on Experimental Forests and Ranges

    Treesearch

    Monica Tomosy; Scott H. Stoleson; David I. King

    2011-01-01

    In August of 2009 a symposium was convened at the 127th Stated Meeting of the American Ornithologist's Union in Philadelphia, Pennsylvania to commemorate the 100th anniversary of the nationwide system of Experimental Forests and Ranges (EFRs) established by the US Forest Service in 1909. Fifteen scientists from across the United States and the Caribbean gathered...

  19. Relationships between fire danger and the daily number and daily growth of active incidents burning in the northern Rocky Mountains, USA

    Treesearch

    Patrick H. Freeborn; Mark A. Cochrane; W. Matt Jolly

    2015-01-01

    Daily National Fire Danger Rating System (NFDRS) indices are typically associated with the number and final size of newly discovered fires, or averaged over time and associated with the likelihood and total burned area of large fires. Herein we used a decade (2003-12) of NFDRS indices and US Forest Service (USFS) fire reports to examine daily relationships between fire...

  20. Estimates of carbon stored in harvested wood products from United States Forest Service's Sierra Nevada Bio-Regional Assessment Area of the Pacific Southwest Region, 1909-2012

    Treesearch

    Keith Stockmann; Nathaniel Anderson; Jesse Young; Ken Skog; Sean Healey; Dan Loeffler; Edward Butler; J. Greg Jones; James Morrison

    2014-01-01

    Global forests capture and store significant amounts of carbon through photosynthesis. When carbon is removed from forests through harvest, a portion of the harvested carbon is stored in wood products, often for many decades. The United States Forest Service (USFS) and other agencies are interested in accurately accounting for carbon flux associated with harvested wood...

  1. Use of Knowledge Base Systems (EMDS) in Strategic and Tactical Forest Planning

    NASA Astrophysics Data System (ADS)

    Jensen, M. E.; Reynolds, K.; Stockmann, K.

    2008-12-01

    The USDA Forest Service 2008 Planning Rule requires Forest plans to provide a strategic vision for maintaining the sustainability of ecological, economic, and social systems across USFS lands through the identification of desired conditions and objectives. In this paper we show how knowledge-based systems can be efficiently used to evaluate disparate natural resource information to assess desired conditions and related objectives in Forest planning. We use the Ecosystem Management Decision Support (EMDS) system (http://www.institute.redlands.edu/emds/), which facilitates development of both logic-based models for evaluating ecosystem sustainability (desired conditions) and decision models to identify priority areas for integrated landscape restoration (objectives). The study area for our analysis spans 1,057 subwatersheds within western Montana and northern Idaho. Results of our study suggest that knowledge-based systems such as EMDS are well suited to both strategic and tactical planning and that the following points merit consideration in future National Forest (and other land management) planning efforts: 1) Logic models provide a consistent, transparent, and reproducible method for evaluating broad propositions about ecosystem sustainability such as: are watershed integrity, ecosystem and species diversity, social opportunities, and economic integrity in good shape across a planning area? The ability to evaluate such propositions in a formal logic framework also allows users the opportunity to evaluate statistical changes in outcomes over time, which could be very useful for regional and national reporting purposes and for addressing litigation; 2) The use of logic and decision models in strategic and tactical Forest planning provides a repository for expert knowledge (corporate memory) that is critical to the evaluation and management of ecosystem sustainability over time. This is especially true for the USFS and other federal resource agencies, which are likely to experience rapid turnover in tenured resource specialist positions within the next five years due to retirements; 3) Use of logic model output in decision models is an efficient method for synthesizing the typically large amounts of information needed to support integrated landscape restoration. Moreover, use of logic and decision models to design customized scenarios for integrated landscape restoration, as we have demonstrated with EMDS, offers substantial improvements to traditional GIS-based procedures such as suitability analysis. To our knowledge, this study represents the first attempt to link evaluations of desired conditions for ecosystem sustainability in strategic planning to tactical planning regarding the location of subwatersheds that best meet the objectives of integrated landscape restoration. The basic knowledge-based approach implemented in EMDS, with its logic (NetWeaver) and decision (Criterion Decision Plus) engines, is well suited both to multi-scale strategic planning and to multi-resource tactical planning.

  2. Smokey the Bear Toy floating in the Node 1

    NASA Image and Video Library

    2012-08-03

    ISS032-E-011664 (3 Aug. 2012) --- Smokey Bear floats freely in the hatchway of the International Space Station’s Destiny laboratory. On May 15, 2012, Smokey traveled aboard the Soyuz spacecraft with NASA astronaut Joe Acaba and Russian cosmonauts Gennady Padalka and Sergei Revin to the space station. As a recognized symbol for wildland fire prevention, his presence on the orbiting complex also highlights the many areas of active space station research related to Earth observations, plant growth and combustion and materials sciences, as well as existing spinoff technologies in these areas. NASA, the U.S. Forest Service (USFS) and the Texas Forest Service are teaming up to celebrate Smokey's 68th birthday Aug. 9 at NASA's Johnson Space Center in Houston.

  3. Smokey the Bear Toy floating in the Node 1

    NASA Image and Video Library

    2012-08-03

    ISS032-E-011666 (3 Aug. 2012) --- Smokey Bear floats freely in the hatchway of the International Space Station’s Destiny laboratory. On May 15, 2012, Smokey traveled aboard the Soyuz spacecraft with NASA astronaut Joe Acaba and Russian cosmonauts Gennady Padalka and Sergei Revin to the space station. As a recognized symbol for wildland fire prevention, his presence on the orbiting complex also highlights the many areas of active space station research related to Earth observations, plant growth and combustion and materials sciences, as well as existing spinoff technologies in these areas. NASA, the U.S. Forest Service (USFS) and the Texas Forest Service are teaming up to celebrate Smokey's 68th birthday Aug. 9 at NASA's Johnson Space Center in Houston.

  4. Smokey the Bear Toy in the Node 1

    NASA Image and Video Library

    2012-08-03

    ISS032-E-011662 (3 Aug. 2012) --- Smokey Bear floats freely in the Unity node of the International Space Station. On May 15, 2012, Smokey traveled aboard the Soyuz spacecraft with NASA astronaut Joe Acaba and Russian cosmonauts Gennady Padalka and Sergei Revin to the space station. As a recognized symbol for wildland fire prevention, his presence on the orbiting complex also highlights the many areas of active space station research related to Earth observations, plant growth and combustion and materials sciences, as well as existing spinoff technologies in these areas. NASA, the U.S. Forest Service (USFS) and the Texas Forest Service are teaming up to celebrate Smokey's 68th birthday Aug. 9 at NASA's Johnson Space Center in Houston.

  5. Smokey the Bear Toy in the Node 1

    NASA Image and Video Library

    2012-08-03

    ISS032-E-011654 (3 Aug. 2012) --- Smokey Bear floats freely near crew insignias placed in the Unity node of the International Space Station. On May 15, 2012, Smokey traveled aboard the Soyuz spacecraft with NASA astronaut Joe Acaba and Russian cosmonauts Gennady Padalka and Sergei Revin to the space station. As a recognized symbol for wildland fire prevention, his presence on the orbiting complex also highlights the many areas of active space station research related to Earth observations, plant growth and combustion and materials sciences, as well as existing spinoff technologies in these areas. NASA, the U.S. Forest Service (USFS) and the Texas Forest Service are teaming up to celebrate Smokey's 68th birthday Aug. 9 at NASA's Johnson Space Center in Houston.

  6. Role of MODIS Vegetation Phenology Products in the U.S. for Warn Early Warning System for Forest Threats

    NASA Technical Reports Server (NTRS)

    Spruce, Joseph; Hargrove, William; Norman, Steve; Gasser, Gerald; Smoot, James; Kuper, Philip

    2012-01-01

    U.S. forests occupy approx 751 million acres (approx 1/3 of total land). Several abiotic and biotic damage agents disturb, damage, kill, and/or threaten these forests. Regionally extensive forest disturbances can also threaten human life and property, bio-diversity and water supplies. timely regional forest disturbance monitoring products are needed to aid forest health management work at finer scales. daily MODIS data provide a means to monitor regional forest disturbances on a weekly basis, leveraging vegetation phenology. In response, the USFS and NASA began collaborating in 2006 to develop a Near Real Time (NRT) forest monitoring capability, based on MODIS NDVI data, as part of a national forest threat Early Warning System (EWS).

  7. Simulations of Potential Runout and Deposition of the Ferguson Rockslide, Merced River Canyon, California

    USGS Publications Warehouse

    Denlinger, Roger P.

    2007-01-01

    INTRODUCTION An active rockslide in Merced River Canyon was first noticed on April 29, 2006 when a few rocks rolled onto Highway 140 between mileposts 103 and 104, compromising traffic on this highway and signaling the onset of renewed activity of the Ferguson rockslide. State highway 140 is one of the main entrances to Yosemite National Park and is the primary road for large commercial trucks access into the park from the west. Continued rockslide activity during 2006 built a large talus cone that covered the highway and encroached into the Merced River below it. Observations by the US Forest Service (USFS), the California Department of Transportation (CALTRANS), and the U.S. Geological Survey (USGS) confirm that the rockslide remained active through 2006 and represents a potential threat to traffic along the rerouted highway as well as to recreational users of the Merced River in the runout path below the rockslide. Delineation of the hazards posed by the Ferguson rockslide is a necessary prerequisite to mitigating them. Field observations of the rockslide, shown in the photo of Figure 1, have constrained the geometry and structure of the slide mass (Beck, 2006; Gallegos and DeGraff, 2006). Based on initial estimates by geologists from USFS, CALTRANS and the USGS, the rockslide, active in 2006 and 2007, has an area of approximately 40,000 square meters and a volume of approximately 800,000 cubic meters. Structural mapping suggests that the motion of the slide is translational along a planar bed, and that differential motion of the slide from the toe to the headwall has resulted in formation of large tension cracks that transect the slide across the slope (Beck, 2006). These indications of persistent movement were confirmed during 2006 and 2007 by GPS measurements made by the USGS at three points on the rockslide (Rick LaHusen, USGS, written communication). The larger of these cracks divide the slide into regions that moved at different rates in 2006, with the toe of the rockslide moving five to ten times faster than the middle portion or headwall part of the slide. Downslope of the main rockslide mass, a talus slope consist in of angular blocks ranging in size from 0.1 to greater than 10 meters (Gallegos and DeGraff, 2006), buries Highway 140. Both the main rockslide and the talus consist of angular blocks ranging in size from 0.1 to more than 10 meters and are composed of highly fractured phyllite, slate, and chert from the Phyllite and Chert of Hite Cove (Bateman and Krauskopf, 1987). The purpose of this report is to assess the hazard posed by the Ferguson rockslide by simulating the runout and deposition of a portion of the slide if rapid failure occurs. As discussed by Gallegos and DeGraf (2006), a runout analysis is needed to delineate slide hazards. The report is restricted to calculations of potential runout and does not address the likelihood of rapid failure. Based on discussions with Allan Gallegos (USFS), two end-member initial slide volumes were chosen: (1) the toe of the slide along boundaries defined by Tim Beck (CALTRANS) in (Beck, 2006), and (2) the entire sliding rock mass, again along boundaries defined by Tim Beck. The simulated runout of these volumes during rapid failure uses granular flow mechanics developed by Iverson (1997) and the model developed by Denliner and Iverson, (2004). This model has been thoroughly tested against experimental data and provides plausible, defensible results.

  8. South Fork Flathead Watershed Westslope Cutthroat Trout Conservation Program, Annual Report 2002.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Grisak, Grant; Marotz, Brian

    2003-06-01

    In 1999, Montana Fish, Wildlife & Parks (MFWP) began a program aimed at conserving the genetically pure populations of westslope cutthroat trout in the South Fork Flathead River drainage. The objective of this program is to eliminate all of the exotic and hybrid trout that threaten the genetically pure westslope cutthroat populations in the South Fork Flathead. The exotic and hybrid trout populations occur in several headwater lakes and their outflow streams. In 2001 MFWP released a draft environmental assessment, pursuant to the Montana Environmental Policy Act (MEPA), that addressed the use of motorized equipment to deliver personnel and materialsmore » to some of these lakes in the Bob Marshall and Great Bear Wildernesses (Grisak 2001). After a 30-day public comment period, MFWP determined that the complexity of issues was too great and warranted a more detailed analysis. These issues included transportation options for personnel, equipment and materials, the use of motorized equipment in wilderness, fish removal methods, fish stocking, and the status and distribution of amphibian populations in the project area. Because the program also involves the U.S. Forest Service (USFS) and Bonneville Power Administration (BPA), the environmental analysis needs to comply with the National Environmental Policy Act (NEPA). In October 2001, pursuant to NEPA, MFWP, along with the USFS and BPA initiated an environmental assessment to address these issues. In June 2002, the three agencies determined that the scope of these issues warranted an Environmental Impact Statement. This specialist report describes the logistical, technical and biological issues associated with this project and provides an analysis of options for fish removal, transportation and fish stocking. It further analyzes issues and concerns associated with amphibian populations and creating new domesticated stocks of westslope cutthroat trout. Finally, this document provides a description of each lake, the best method of fish removal that would achieve the goals of the project, logistics for carrying out the fish removal, and the immediate management direction for each lake following fish removal. The USFS is preparing a specialist report detailing land management issues that relate to National Forest, designated Hiking Areas, and Wilderness. Information from these two documents will be used by BPA to prepare an Environmental Impact Statement.« less

  9. Automated system for smoke dispersion prediction due to wild fires in Alaska

    NASA Astrophysics Data System (ADS)

    Kulchitsky, A.; Stuefer, M.; Higbie, L.; Newby, G.

    2007-12-01

    Community climate models have enabled development of specific environmental forecast systems. The University of Alaska (UAF) smoke group was created to adapt a smoke forecast system to the Alaska region. The US Forest Service (USFS) Missoula Fire Science Lab had developed a smoke forecast system based on the Weather Research and Forecasting (WRF) Model including chemistry (WRF/Chem). Following the successful experience of USFS, which runs their model operationally for the contiguous U.S., we develop a similar system for Alaska in collaboration with scientists from the USFS Missoula Fire Science Lab. Wildfires are a significant source of air pollution in Alaska because the climate and vegetation favor annual summer fires that burn huge areas. Extreme cases occurred in 2004, when an area larger than Maryland (more than 25000~km2) burned. Small smoke particles with a diameter less than 10~μm can penetrate deep into lungs causing health problems. Smoke also creates a severe restriction to air transport and has tremendous economical effect. The smoke dispersion and forecast system for Alaska was developed at the Geophysical Institute (GI) and the Arctic Region Supercomputing Center (ARSC), both at University of Alaska Fairbanks (UAF). They will help the public and plan activities a few days in advance to avoid dangerous smoke exposure. The availability of modern high performance supercomputers at ARSC allows us to create and run high-resolution, WRF-based smoke dispersion forecast for the entire State of Alaska. The core of the system is a Python program that manages the independent pieces. Our adapted Alaska system performs the following steps \\begin{itemize} Calculate the medium-resolution weather forecast using WRF/Met. Adapt the near real-time satellite-derived wildfire location and extent data that are received via direct broadcast from UAF's "Geographic Information Network of Alaska" (GINA) Calculate fuel moisture using WRF forecasts and National Fire Danger Rating System (NFDRS) fuel maps Calculate smoke emission components using a first order fire emission model Model the smoke plume rise yielding a vertically distribution that accounts for one-dimensional (vertical) concentrations of smoke constituents in the atmosphere above the fire Run WRF/Chem at high resolution for the forecast Use standard graphical tools to provide accessible smoke dispersion The system run twice each day at ARSC. The results will be freely available from a dedicated wildfire smoke web portal at ARSC.

  10. Coordinating the IUCN red list of North American tree species: a special session at the USFS gene conservation of tree species workshop

    Treesearch

    Murphy Westwood; Anne Frances; Gary Man; David Pivorunas; Kevin M. Potter

    2017-01-01

    Conservation status assessments are a valuable tool for the management and protection of rare and endangered species. Categorizing and defining rarity, threats, and population trends is often the first step toward understanding and documenting the health of the world’s plant diversity. Having up to date conservation status assessments for all of North America’s native...

  11. Bridging the gap between data analysis and data collection in FIA and forest monitoring globally: successes, research findings, and lessons learned from the Western US and Southeast Asia

    Treesearch

    Leif Mortenson

    2015-01-01

    Globally, national forest inventories (NFI) require a large work force typically consisting of multiple teams spread across multiple locations in order to successfully capture a given nation’s forest resources. This is true of the Forest Inventory and Analysis (FIA) program in the US and in many inventories in developing countries that are supported by USFS...

  12. Evaluation of Planning for Fish and Wildlife at Corps of Engineers Reservoirs, Allegheny Reservoir Project, Pennsylvania.

    DTIC Science & Technology

    1982-09-01

    hunters presently reside within known drawing dis- tance of the project area. To this number ay be added approximately 64,000 unlicensed children and...approximately 770,000 licensed fishermen and about 260,000 unlicensed children and retired adults who fish. Depending upon the quality of the project...Allegheny National Forest, USFS, porn . Comm., 1981). Average annual warnuater angling man-day use on Allegheny Lake was esti- mated at approximately 166,700

  13. Ending the U.S. War in Iraq: The Final Transition, Operational Maneuver, and Disestablishment of United States Forces-Iraq

    DTIC Science & Technology

    2013-01-01

    management survey and ensure that all databases (military and contracted civilian), key leader engagement logs, assistance project files, and other...Princeton University Press, 2000; Michael I. Handel, War Termination—A Critical Survey , Jeru- salem: Hebrew University, 1978; Jane Holl Lute, From the...DoS did not plan to install permanent and more costly security measures.133 Security surveys undertaken collaboratively by USF-I and multiple

  14. Nuclear criticality safety evaluation of SRS 9971 shipping package

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vescovi, P.J.

    1993-02-01

    This evaluation is requested to revise the criticality evaluation used to generate Chapter 6 (Criticality Evaluation) of the Safety Analysis Report for Packaging (SARP) for shipment Of UO{sub 3} product from the Uranium Solidification Facility (USF) in the SRS 9971 shipping package. The pertinent document requesting this evaluation is included as Attachment I. The results of the evaluation are given in Attachment II which is written as Chapter 6 of a NRC format SARP.

  15. Soil, environmental, and watershed measurements in support of carbon cycling studies in northwestern Mississippi

    USGS Publications Warehouse

    Huntington, T.G.; Harden, J.W.; Dabney, S.M.; Marion, D.A.; Alonso, C.; Sharpe, J.M.; Fries, T.L.

    1998-01-01

    Measurements including soil respiration, soil moisture, soil temperature, and carbon export in suspended sediments from small watersheds were recorded at several field sites in northwestern Mississippi in support of hillslope process studies associated with the U.S. Geological Survey's Mississippi Basin Carbon Project (MBCP). These measurements were made to provide information about carbon cycling in agricultural and forest ecosystems to understand the potential role of erosion and deposition in the sequestration of soil organic carbon in upland soils. The question of whether soil erosion and burial constitutes an important net sink of atmospheric carbon dioxide is one hypothesis that the MBCP is evaluating to better understand carbon cycling and climate change. This report contains discussion of methods used and presents data for the period December 1996 through March 1998. Included in the report are ancillary data provided by the U.S. Department of Agriculture (USDA) ARS National Sedimentation Laboratory and U.S. Forest Service (USFS) Center for Bottomland Hardwoods Research on rainfall, runoff, sediment yield, forest biomass and grain yield. Together with the data collected by the USGS these data permit the construction of carbon budgets and the calibration of models of soil organic matter dynamics and sediment transport and deposition. The U.S. Geological Survey (USGS) has established cooperative agreements with the USDA and USFS to facilitate collaborative research at research sites in northwestern Mississippi.

  16. Non-Traditional Education: Modalities and Implications for Higher Education.

    ERIC Educational Resources Information Center

    Ash, Barbara F.

    Nontraditional approaches in higher education are discussed, with attention to: (1) economic and philosophical reasons for nontraditional education; (2) future thrusts; (3) nontraditional instructional modalities; and (4) the implications for higher education of the extensive use of nontraditional approaches. It is suggested that nontraditional…

  17. Chromatin insulator elements: establishing barriers to set heterochromatin boundaries.

    PubMed

    Barkess, Gráinne; West, Adam G

    2012-02-01

    Epigenomic profiling has revealed that substantial portions of genomes in higher eukaryotes are organized into extensive domains of transcriptionally repressive chromatin. The boundaries of repressive chromatin domains can be fixed by DNA elements known as barrier insulators, to both shield neighboring gene expression and to maintain the integrity of chromosomal silencing. Here, we examine the current progress in identifying vertebrate barrier elements and their binding factors. We overview the design of the reporter assays used to define enhancer-blocking and barrier insulators. We look at the mechanisms vertebrate barrier proteins, such as USF1 and VEZF1, employ to counteract Polycomb- and heterochromatin-associated repression. We also undertake a critical analysis of whether CTCF could also act as a barrier protein. There is good evidence that barrier elements in vertebrates can form repressive chromatin domain boundaries. Future studies will determine whether barriers are frequently used to define repressive domain boundaries in vertebrates.

  18. Innovative Method for Developing a Helium Pressurant Tank Suitable for the Upper Stage Flight Experiment

    NASA Technical Reports Server (NTRS)

    DeLay, Tom K.; Munafo, Paul (Technical Monitor)

    2001-01-01

    The AFRL USFE project is an experimental test bed for new propulsion technologies. It will utilize ambient temperature fuel and oxidizers (Kerosene and Hydrogen peroxide). The system is pressure fed, not pump fed, and will utilize a helium pressurant tank to drive the system. Mr. DeLay has developed a method for cost effectively producing a unique, large pressurant tank that is not commercially available. The pressure vessel is a layered composite structure with an electroformed metallic permeation barrier. The design/process is scalable and easily adaptable to different configurations with minimal cost in tooling development 1/3 scale tanks have already been fabricated and are scheduled for testing. The full-scale pressure vessel (50" diameter) design will be refined based on the performance of the sub-scale tank. The pressure vessels have been designed to operate at 6,000 psi. a PV/W of 1.92 million is anticipated.

  19. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Salasovich, James; LoVullo, David; Kandt, Alicen

    This report summarizes results from the energy efficiency, water efficiency, and renewable energy site assessment of the Mendenhall Glacier Visitor Center and site in Juneau, Alaska. The assessment is an American Society of Heating, Refrigerating, and Air-Conditioning Engineers Level 2 audit and meets Energy Independence and Security Act requirements. A team led by the U.S. Department of Energy's National Renewable Energy Laboratory conducted the assessment with U.S. Forest Service personnel August 19-20, 2015, as part of ongoing efforts by USFS to reduce energy and water use.

  20. Flash fire propensity of materials

    NASA Technical Reports Server (NTRS)

    Hilado, C. J.; Cumming, H. J.

    1977-01-01

    Flash fire test results on 86 materials, evaluated using the USF flash fire screening test, are presented. The materials which appear least prone to flash fires are PVC, polyphenylene oxide and sulfide, and polyether and polyaryl sulfone; these did not produce flash fires under these particular test conditions. The principal value of these screening tests at the present time is in identifying materials which appear prone to flash fires, and in identifying which formulations of a generic material are more or less prone to flash fires.

  1. Nuclear criticality safety evaluation of SRS 9971 shipping package. [SRS (Savannah River Site)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vescovi, P.J.

    1993-02-01

    This evaluation is requested to revise the criticality evaluation used to generate Chapter 6 (Criticality Evaluation) of the Safety Analysis Report for Packaging (SARP) for shipment Of UO[sub 3] product from the Uranium Solidification Facility (USF) in the SRS 9971 shipping package. The pertinent document requesting this evaluation is included as Attachment I. The results of the evaluation are given in Attachment II which is written as Chapter 6 of a NRC format SARP.

  2. Interpreting forest biome productivity and cover utilizing nested scales of image resolution and biogeographical analysis

    NASA Technical Reports Server (NTRS)

    Iverson, Louis R.; Cook, Elizabeth A.; Graham, Robin L.; Olson, Jerry S.; Frank, Thomas D.; Ying, KE

    1988-01-01

    The objective was to relate spectral imagery of varying resolution with ground-based data on forest productivity and cover, and to create models to predict regional estimates of forest productivity and cover with a quantifiable degree of accuracy. A three stage approach was outlined. In the first stage, a model was developed relating forest cover or productivity to TM surface reflectance values (TM/FOREST models). The TM/FOREST models were more accurate when biogeographic information regarding the landscape was either used to stratigy the landscape into more homogeneous units or incorporated directly into the TM/FOREST model. In the second stage, AVHRR/FOREST models that predicted forest cover and productivity on the basis of AVHRR band values were developed. The AVHRR/FOREST models had statistical properties similar to or better than those of the TM/FOREST models. In the third stage, the regional predictions were compared with the independent U.S. Forest Service (USFS) data. To do this regional forest cover and forest productivity maps were created using AVHRR scenes and the AVHRR/FOREST models. From the maps the county values of forest productivity and cover were calculated. It is apparent that the landscape has a strong influence on the success of the approach. An approach of using nested scales of imagery in conjunction with ground-based data can be successful in generating regional estimates of variables that are functionally related to some variable a sensor can detect.

  3. Different historical fire–climate patterns in California

    USGS Publications Warehouse

    Keeley, Jon E.; Syphard, Alexandra D.

    2017-01-01

    The relationship between annual variation in area burned and seasonal temperatures and precipitation was investigated for the major climate divisions in California. Historical analyses showed marked differences in fires on montane and foothill landscapes. Based on roughly a century of data, there are five important lessons on fire–climate relationships in California: (1) seasonal variations in temperature appear to have had minimal influence on area burned in the lower elevation, mostly non-forested, landscapes; (2) temperature has been a significant factor in controlling fire activity in higher elevation montane forests, but this varied greatly with season – winter and autumn temperatures showed no significant effect, whereas spring and summer temperatures were important determinants of area burned; (3) current season precipitation has been a strong controller of fire activity in forests, with drier years resulting in greater area burned on most United States Forest Service (USFS) lands in the state, but the effect of current-year precipitation was decidedly less on lower elevation California Department of Forestry and Fire Protection lands; (4) in largely grass-dominated foothills and valleys the magnitude of prior-year rainfall was positively tied to area burned in the following year, and we hypothesise that this is tied to greater fuel volume in the year following high rainfall. In the southern part of the state this effect has become stronger in recent decades and this likely is due to accelerated type conversion from shrubland to grassland in the latter part of the 20th century; (5) the strongest fire–climate models were on USFS lands in the Sierra Nevada Mountains, and these explained 42–52% of the variation in area burned; however, the models changed over time, with winter and spring precipitation being the primary drivers in the first half of the 20th century, but replaced by spring and summer temperatures after 1960.

  4. Upper-Stage Flight Experiment

    NASA Technical Reports Server (NTRS)

    Anderson, W. E.; Boxwell, R.; Crockett, D. V.; Ross, R.; Lewis, T.; McNeal, C.; Verdarame, K.

    1999-01-01

    For propulsion applications that require that the propellants are storable for long periods, have a high density impulse, and are environmentally clean and non-toxic, the best choice is a combination of high-concentration hydrogen peroxide (High Test Peroxide, or HTP) and a liquid hydrocarbon (LHC) fuel. The HTP/LHC combination is suitable for low-cost launch vehicles, space taxi and space maneuvering vehicles, and kick stages. Orbital Sciences Corporation is under contract with the NASA Marshall Space Flight Center in cooperation with the Air Force Research Lab to design, develop and demonstrate a new low-cost liquid upper stage based on HTP and JP-8. The Upper Stage Flight Experiment (USFE) focuses on key technologies necessary to demonstrate the operation of an inherently simple propulsion system with an innovative, state-of-the-art structure. Two key low-cost vehicle elements will be demonstrated - a 10,000 lbf thrust engine and an integrated composite tank structure. The suborbital flight test of the USFE is scheduled for 2001. Preceding the flight tests are two major series of ground tests at NASA Stennis Space Center and a subscale tank development program to identify compatible composite materials and to verify their compatibility over long periods of time. The ground tests include a thrust chamber development test series and an integrated stage test. This paper summarizes the results from the first phase of the thrust chamber development tests and the results to date from the tank material compatibility tests. Engine and tank configurations that meet the goals of the program are described.

  5. Ocean Sciences as a Foundation for Curriculum Design

    NASA Astrophysics Data System (ADS)

    Rakhmenkulova, I.; Gorshkalev, S.; Odriozola, A.; Dominguez, A.; Greely, T.; Pyrtle, A.; Keiper, T.; Watkins, J.

    2005-05-01

    The GK-12 OCEANS program is an initiative of the National Science Foundation (NSF). This program provides marine science graduate students within the College of Marine Science, USF, weekly interactions with K-12 teachers and students in Pinellas County schools with the overall purpose of enhancing the quality and effectiveness of science teaching. The GK-12 OCEANS program provides hands-on and minds-on ocean science learning inquiries. Campbell Park Elementary is a Marine Science attractor school designed to provide a child-centered approach to learning that integrates marine science activities into the daily curriculum while meeting the required state education standards. In 2003-04 a GK-12 Fellow helped third and fourth grade teachers design new teaching curricula that integrated ocean sciences. The current 2004-04 Fellow and teachers are implementing the new curriculum, assessing feasibility and impact on students' learning. One characteristic of the new curriculum includes several field trips to local natural settings during which students have the opportunity to collect data the way scientists do, and use real scientific instruments and approaches. The information collected is then used in different activities within the classroom. These activities encourage the students to use inquiry as the basis of their learning experience, in which the application of scientific thinking and methods are keys. This process also requires the students to apply skills from other disciplines such as writing, reading, and math. Towards the end of the school year the students have the opportunity to highlight their accomplishments through two projects, 1) a hall display of different ocean zones, which includes habitat characteristics and species adaptations, and 2) a marine science experiment presented at the school science fair. The results and accomplishments from the implementation of these new curricula will be presented at the conference.

  6. The Simulations of Wildland Fire Smoke PM25 in the NWS Air Quality Forecasting Systems

    NASA Astrophysics Data System (ADS)

    Huang, H. C.; Pan, L.; McQueen, J.; Lee, P.; ONeill, S. M.; Ruminski, M.; Shafran, P.; Huang, J.; Stajner, I.; Upadhayay, S.; Larkin, N. K.

    2017-12-01

    The increase of wildland fire intensity and frequency in the United States (U.S.) has led to property loss, human fatality, and poor air quality due to elevated particulate matters and surface ozone concentrations. The NOAA/National Weather Service (NWS) built the National Air Quality Forecast Capability (NAQFC) based on the U.S. Environmental Protection Agency (EPA) Community Multi-scale Air Quality (CMAQ) Modeling System driven by the NCEP North American Mesoscale Forecast System meteorology to provide ozone and fine particulate matter (PM2.5) forecast guidance publicly. State and local forecasters use the NWS air quality forecast guidance to issue air quality alerts in their area. The NAQFC PM2.5 predictions include emissions from anthropogenic and biogenic sources, as well as natural sources such as dust storms and wildland fires. The wildland fire emission inputs to the NAQFC is derived from the NOAA National Environmental Satellite, Data, and Information Service Hazard Mapping System fire and smoke detection product and the emission module of the U.S. Forest Service (USFS) BlueSky Smoke Modeling Framework. Wildland fires are unpredictable and can be ignited by natural causes such as lightning or be human-caused. It is extremely difficult to predict future occurrences and behavior of wildland fires, as is the available bio-fuel to be burned for real-time air quality predictions. Assumptions of future day's wildland fire behavior often have to be made from older observed wildland fire information. The comparisons between the NAQFC modeled PM2.5 and the EPA AirNow surface observation show that large errors in PM2.5 prediction can occur if fire smoke emissions are sometimes placed at the wrong location and/or time. A configuration of NAQFC CMAQ-system to re-run previous 24 hours, during which wildland fires were observed from satellites has been included recently. This study focuses on the effort performed to minimize the error in NAQFC PM2.5 predictions resulting from incorporating fire smoke emissions into the NAQFC from a recently updated newer version of USFS BlueSky system. This study will show how new approaches has improved the PM2.5 predictions at both nearby and downstream areas from fire sources. Furthermore, Environment and Climate Change Canada (ECCC) fire emissions data are being tested.

  7. Grid-Independent Large-Eddy Simulation in Turbulent Channel Flow using Three-Dimensional Explicit Filtering

    NASA Technical Reports Server (NTRS)

    Gullbrand, Jessica

    2003-01-01

    In this paper, turbulence-closure models are evaluated using the 'true' LES approach in turbulent channel flow. The study is an extension of the work presented by Gullbrand (2001), where fourth-order commutative filter functions are applied in three dimensions in a fourth-order finite-difference code. The true LES solution is the grid-independent solution to the filtered governing equations. The solution is obtained by keeping the filter width constant while the computational grid is refined. As the grid is refined, the solution converges towards the true LES solution. The true LES solution will depend on the filter width used, but will be independent of the grid resolution. In traditional LES, because the filter is implicit and directly connected to the grid spacing, the solution converges towards a direct numerical simulation (DNS) as the grid is refined, and not towards the solution of the filtered Navier-Stokes equations. The effect of turbulence-closure models is therefore difficult to determine in traditional LES because, as the grid is refined, more turbulence length scales are resolved and less influence from the models is expected. In contrast, in the true LES formulation, the explicit filter eliminates all scales that are smaller than the filter cutoff, regardless of the grid resolution. This ensures that the resolved length-scales do not vary as the grid resolution is changed. In true LES, the cell size must be smaller than or equal to the cutoff length scale of the filter function. The turbulence-closure models investigated are the dynamic Smagorinsky model (DSM), the dynamic mixed model (DMM), and the dynamic reconstruction model (DRM). These turbulence models were previously studied using two-dimensional explicit filtering in turbulent channel flow by Gullbrand & Chow (2002). The DSM by Germano et al. (1991) is used as the USFS model in all the simulations. This enables evaluation of different reconstruction models for the RSFS stresses. The DMM consists of the scale-similarity model (SSM) by Bardina et al. (1983), which is an RSFS model, in linear combination with the DSM. In the DRM, the RSFS stresses are modeled by using an estimate of the unfiltered velocity in the unclosed term, while the USFS stresses are modeled by the DSM. The DSM and the DMM are two commonly used turbulence-closure models, while the DRM is a more recent model.

  8. Transcriptional regulation of hepatic lipogenesis.

    PubMed

    Wang, Yuhui; Viscarra, Jose; Kim, Sun-Joong; Sul, Hei Sook

    2015-11-01

    Fatty acid and fat synthesis in the liver is a highly regulated metabolic pathway that is important for very low-density lipoprotein (VLDL) production and thus energy distribution to other tissues. Having common features at their promoter regions, lipogenic genes are coordinately regulated at the transcriptional level. Transcription factors, such as upstream stimulatory factors (USFs), sterol regulatory element-binding protein 1C (SREBP1C), liver X receptors (LXRs) and carbohydrate-responsive element-binding protein (ChREBP) have crucial roles in this process. Recently, insights have been gained into the signalling pathways that regulate these transcription factors. After feeding, high blood glucose and insulin levels activate lipogenic genes through several pathways, including the DNA-dependent protein kinase (DNA-PK), atypical protein kinase C (aPKC) and AKT-mTOR pathways. These pathways control the post-translational modifications of transcription factors and co-regulators, such as phosphorylation, acetylation or ubiquitylation, that affect their function, stability and/or localization. Dysregulation of lipogenesis can contribute to hepatosteatosis, which is associated with obesity and insulin resistance.

  9. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Petrosky, Charles E.; Holubetz, Terry B.

    The Idaho Department of Fish and Game has been monitoring and evaluating existing and proposed habitat improvement projects for steelhead (Salmo gairdneri) and chinook salmon (Oncorhynchus tshawytscha) in the Clearwater and Salmon River drainages over the last four years. Projects included in the evaluation are funded by, or proposed for funding by, the Bonneville Power Administration (BPA) under the Northwest Power Planning Act as off-site mitigation for downstream hydropower development on the Snake and Columbia rivers. A mitigation record is being developed to use increased smolt production at full seeding as the best measure of benefit from a habitat enhancementmore » project. Determination of full benefit from a project depends on presence of adequate numbers of fish to document actual increases in fish production. The depressed nature of upriver anadromous stocks have precluded attainment of full benefit of any habitat project in Idaho. Partial benefit will be credited to the mitigation record in the interim period of run restoration. According to the BPA Work Plan, project implementors have the primary responsibility for measuring physical habitat and estimating habitat change. To date, Idaho habitat projects have been implemented primarily by the US Forest Service (USFS). The Shoshone-Bannock Tribes (SBT) have sponsored three projects (Bear Valley Mine, Yankee Fork, and the proposed East Fork Salmon River projects). IDFG implemented two barrier-removal projects (Johnson Creek and Boulder Creek) that the USFS was unable to sponsor at that time. The role of IDFG in physical habitat monitoring is primarily to link habitat quality and habitat change to changes in actual, or potential, fish production. Individual papers were processed separately for the data base.« less

  10. Using commercial software products for atmospheric remote sensing

    NASA Astrophysics Data System (ADS)

    Kristl, Joseph A.; Tibaudo, Cheryl; Tang, Kuilian; Schroeder, John W.

    2002-02-01

    The Ontar Corporation (www.Ontar.com) has developed several products for atmospheric remote sensing to calculate radiative transport, atmospheric transmission, and sensor performance in both the normal atmosphere and the atmosphere disturbed by battlefield conditions of smoke, dust, explosives and turbulence. These products include: PcModWin: Uses the USAF standard MODTRAN model to compute the atmospheric transmission and radiance at medium spectral resolution (2 cm-1) from the ultraviolet/visible into the infrared and microwave regions of the spectrum. It can be used for any geometry and atmospheric conditions such as aerosols, clouds and rain. PcLnWin: Uses the USAF standard FASCOD model to compute atmospheric transmission and emission at high (line-by-line) spectral resolution using the HITRAN 2000 database. It can be used over the same spectrum from the UV/visible into the infrared and microwave regions of the spectrum. HitranPC: Computes the absolute high (line-by-line) spectral resolution transmission spectrum of the atmosphere for different temperatures and pressures. HitranPC is a user-friendly program developed by the University of South Florida (USF) and uses the international standard molecular spectroscopic database, HITRAN. LidarPC: A computer program to calculate the Laser Radar/L&n Equation for hard targets and atmospheric backscatter using manual input atmospheric parameters or HitranPC and BETASPEC - transmission and backscatter calculations of the atmosphere. Also developed by the University of South Florida (USF). PcEosael: is a library of programs that mathematically describe aspects of electromagnetic propagation in battlefield environments. 25 modules are connected but can be exercised individually. Covers eight general categories of atmospheric effects, including gases, aerosols and laser propagation. Based on codes developed by the Army Research Lab. NVTherm: NVTherm models parallel scan, serial scan, and staring thermal imagers that operate in the mid and far infrared spectral bands (3 to 12 micrometers wavelength). It predicts the Minimum Resolvable Temperature Difference (MRTD) or just MRT) that can be discriminated by a human when using a thermal imager. NVTherm also predicts the target acquisition range performance likely to be achieved using the sensor.

  11. Use of Bedrock and Geomorphic Mapping Compilations in Assessing Geologic Hazards at Recreation Sites on National Forests in NW California

    NASA Astrophysics Data System (ADS)

    de La Fuente, J. A.; Bell, A.; Elder, D.; Mowery, R.; Mikulovsky, R.; Klingel, H.; Stevens, M.

    2010-12-01

    Geologic hazards on US Forest Service lands have a long history of producing catastrophic events. In 1890 (prior to the establishment of the Forest Service), the China Mine landslide buried a miner’s camp along the Trinity River in NW California, killing a number of miners. An earthquake in southwestern Montana triggered a massive landslide which killed 28 people in a US Forest Service campground in 1959. In 1980, Mount St. Helens erupted in Oregon, killing 57 people. Debris flows from a winter storm in 2003 on the burned hillslopes of the San Bernardino National Forest in California killed 14 people at the St. Sophia youth Camp. A rockfall in the summer of 2009 in Lassen National Park killed a 9 year old boy. The most recent catastrophe occurred on June 11, 2010 when 20 people died in a flash flood at the Albert Pike Campground on the Ouachita National Forest. These and other disasters point out the need for geologic hazard mapping and assessments on the National Forests. The US Forest Service (USFS) is currently assessing geologic hazards in the Northern Province of USFS Region 5 (Pacific Southwest Region), which includes the Klamath, Mendocino, Shasta-Trinity, and Six Rivers National Forests. The most common geologic hazards (relatively short return intervals) in this area include landslides, rock falls, debris flows, flooding, temporary dam failures (landslide or woody debris), naturally occurring hazardous materials, (asbestos radon, etc), and rarely, karst subsidence. Seismic and volcanic hazards are also important at longer return intervals. This assessment will be conducted in three phases, and is patterned after a process developed by Region 8 of the US Forest Service. The first phase is a reconnaissance level assessment based on existing information such as spatial databases, aerial photos, Digital Elevation Models, State of California Alquist-Priolo Earthquake Fault Zone maps, previous investigations and anecdotal accounts of past events. The bedrock coverage is a compilation of the best available mapping for all National Forests in California. The geomorphic coverage includes features such as active and dormant landslides, alluvial fans, headwall basins, glacial features, and valley inner gorge. Criteria will be developed which utilize elements of this data to evaluate geologic hazards in the vicinity of developed recreation sites. The second phase will be conducted later and involves site specific analyses focusing on areas identified as higher hazard in the first phase, along with verification and updating of phase 1 findings. The third phase will complete any site level geologic or hydrologic investigations, and wrap up the hazard assessment process. A summary report with hazard maps and recommendations will be prepared at the end of each phase. The overriding goal of this project is to provide sound geologic information to managers so they can use a science-based approach in recognizing and managing geologic hazards at recreation sites.

  12. Social Models: Blueprints or Processes?

    ERIC Educational Resources Information Center

    Little, Graham R.

    1981-01-01

    Discusses the nature and implications of two different models for societal planning: (1) the problem-solving process approach based on Karl Popper; and (2) the goal-setting "blueprint" approach based on Karl Marx. (DC)

  13. The complete sequence and promoter activity of the human A-raf-1 gene (ARAF1)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lee, J.E.; Beck, T.W.; Brennscheidt, U.

    1994-03-01

    The raf proto-oncogenes encode cytoplasmic protein serine/threonine kinases, which play a critical role in cell growth and development. One of these, A-raf-1 (human gene symbol, ARAF1), which is predominantly expressed in mouse urogenital tissues, has been mapped to an evolutionarily conserved linkage group composed of ARAF1, SYN1, TIMP, and properdin located at human chromosome Xp11.2. The authors have isolated human genomic DNA clones containing the expressed gene (ARAF1) on the X chromosome and a pseudogene (ARAF2) on chromosome 7p12-q11.21. Analysis of the nucleotide sequence from the ARAF1 genomic clones demonstrated that it consists of 16 exons encoded by minimally 10,776more » nucleotides. The major transcriptional start site (+1) was determined by RNase protection and primer extension assays. Promoter activity was confirmed by functional assays using DNA fragments fused to a CAT reporter gene. The ARAF1 minimal promoter, located between nucleotides -59 and +93, has a low G + C content and lacks consensus TATA and Inr sequences but shows sequence similarity at position -1 to the E box that is known to interact with USF and TFII-I transcription factors. 65 refs., 7 figs., 1 tab.« less

  14. A Systems Approach to Diagnostic Prescriptive Instruction.

    ERIC Educational Resources Information Center

    Kozma, Robert B.; And Others

    This five-part document presents three approaches to research on instructional improvement, with the final two sections concentrating on problems and implications for diagnostic prescriptive instruction. Part 1 reviews comparative instructional effectiveness studies. Part 2 discusses the Trait-Treatment Interaction Approach (TTI) which is…

  15. A Multi-stakeholder Approach to Moving Beyond Tree Mortality in the Sierra Nevada

    NASA Astrophysics Data System (ADS)

    Balachowski, J.; Buluc, L.; Fischer, C.; Ko, J.; Ostoja, S.

    2017-12-01

    The US Forest Service has estimated that 102 million trees have died in California since 2010. This die off event has been attributed to the combined effects of historical land management practices, fire suppression, insect outbreaks, and climate-related stressors. This tree mortality event represents the largest and most significant ecological disturbance in California in centuries, if not longer. Both scientists and managers recognize the need to rethink our approach to forest management in the face of a changing climate and increasingly frequent, uncharacteristically large wildfires, while budgets and staffing capacity continue to decrease. Addressing the uncertainly in managing under climate change with fewer financial resources will require multiple partners and stakeholders—including federal and state agencies, local governments, and non-governmental organizations—to work together to identify common goals and paths moving forward. The USDA California Climate Hub and USFS Region 5 convened a symposium on drought and tree mortality in July 2017. With nearly 170 attendees across a wide range of sectors, the event provided a meaningful opportunity for reflection, analysis, and consideration of next steps. Among the outcomes of this symposium was the identification of areas in which our capacity for individual and synergistic action is stronger, and those in which it is lacking that will thus require additional attention and effort. From this symposium, which included a series of smaller, stakeholder and partner working groups, we collectively identified research and information needs, possible policy adjustments, future management actions, and funding needs and opportunities. Here, we present these findings and suggest approaches for addressing the current tree mortality event based on the shared interests of multiple, diverse stakeholder groups.

  16. THE NEIGHBORHOOD YOUTH CORPS AND THE COMMUNITY, AN EXPLORATORY STUDY OF THE IMPLICATIONS OF A FEDERAL ANTI-POVERTY PROGRAM FOR MILWAUKEE, WISCONSIN.

    ERIC Educational Resources Information Center

    CARO, FRANCIS G.

    TWO APPROACHES WERE USED IN STUDYING THE EFFECTS OF THE NEIGHBORHOOD YOUTH CORPS (NYC) ON MILWAUKEE, WISCONSIN -- (1) IMPLICATIONS FOR THE INTERNAL AND EXTERNAL OPERATIONS OF ORGANIZATIONS INVOLVED IN ITS WORK FLOW, AND (2) IMPLICATIONS FOR SPECIFIC PROBLEMS IN THE YOUTH AND POVERTY AREAS (SCHOOL ATTENDANCE AND ACHIEVEMENT, JUVENILE DELINQUENCY,…

  17. 78 FR 40497 - Notice of Availability of the Final Environmental Impact Statement/Environmental Impact Report...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-05

    ...In accordance with the National Environmental Policy Act of 1969, as amended (NEPA); the Federal Land Policy and Management Act of 1976, as amended; and the California Environmental Quality Act of 1970 (CEQA), the Bureau of Land Management (BLM), the United States Forest Service (USFS), and the Great Basin Unified Air Pollution Control District (GBUAPCD), a California State agency, have prepared a Final Environmental Impact Statement (EIS)/Environmental Impact Report (EIR) for the proposed Casa Diablo IV Geothermal Development Project near the town of Mammoth Lakes in Mono County, California, and by this notice are announcing its availability.

  18. Studies with the USF/NASA toxicity screening test method - Exercise wheels and oxygen replenishment

    NASA Technical Reports Server (NTRS)

    Hilado, C. J.; Cumming, H. J.

    1977-01-01

    Continuing efforts to improve the University of San Francisco/NASA toxicity screening test method have included the addition of exercise wheels to provide a different measure of incapacitation, and oxygen replenishment to offset any effect of oxygen depletion by the test animals. The addition of exercise wheels limited the number of animals in each test and doubled the required number of tests without any significant improvement in reproducibility. Oxygen replenishment appears to have an effect on survival in the last 5 minutes of the 30-minute test, but the effect is expected to be similar for most materials.

  19. Assessing MODIS-based Products and Techniques for Detecting Gypsy Moth Defoliation

    NASA Technical Reports Server (NTRS)

    Spruce, Joseph P.; Hargrove, William; Smoot, James C.; Prados, Don; McKellip, Rodney; Sader, Steven A.; Gasser, Jerry; May, George

    2008-01-01

    The project showed potential of MODIS and VIIRS time series data for contributing defoliation detection products to the USFS forest threat early warning system. This study yielded the first satellite-based wall-to-wall 2001 gypsy moth defoliation map for the study area. Initial results led to follow-on work to map 2007 gypsy moth defoliation over the eastern United States (in progress). MODIS-based defoliation maps offer promise for aiding aerial sketch maps either in planning surveys and/or adjusting acreage estimates of annual defoliation. More work still needs to be done to assess potential of technology for "now casts"of defoliation.

  20. The Developmental Dialectical Approach to Child Abuse & Neglect.

    ERIC Educational Resources Information Center

    Pakizegi, B.

    A developmental dialectical approach to understanding and working with lower and middle class damaged parents--those identified as abusive and neglectful--has specific features and implications. The approach suggests that (1) the personality characteristics and interpersonal relations of parents are inseparable from their social conditions; (2)…

  1. Potential of VIIRS Time Series Data for Aiding the USDA Forest Service Early Warning System for Forest Health Threats: A Gypsy Moth Defoliation Case Study

    NASA Technical Reports Server (NTRS)

    Spruce, Joseph P.; Ryan, Robert E.; Smoot, James; Kuper, Phillip; Prados, Donald; Russell, Jeffrey; Ross, Kenton; Gasser, Gerald; Sader, Steven; McKellip, Rodney

    2007-01-01

    This report details one of three experiments performed during FY 2007 for the NASA RPC (Rapid Prototyping Capability) at Stennis Space Center. This RPC experiment assesses the potential of VIIRS (Visible/Infrared Imager/Radiometer Suite) and MODIS (Moderate Resolution Imaging Spectroradiometer) data for detecting and monitoring forest defoliation from the non-native Eurasian gypsy moth (Lymantria dispar). The intent of the RPC experiment was to assess the degree to which VIIRS data can provide forest disturbance monitoring information as an input to a forest threat EWS (Early Warning System) as compared to the level of information that can be obtained from MODIS data. The USDA Forest Service (USFS) plans to use MODIS products for generating broad-scaled, regional monitoring products as input to an EWS for forest health threat assessment. NASA SSC is helping the USFS to evaluate and integrate currently available satellite remote sensing technologies and data products for the EWS, including the use of MODIS products for regional monitoring of forest disturbance. Gypsy moth defoliation of the mid-Appalachian highland region was selected as a case study. Gypsy moth is one of eight major forest insect threats listed in the Healthy Forest Restoration Act (HFRA) of 2003; the gypsy moth threatens eastern U.S. hardwood forests, which are also a concern highlighted in the HFRA of 2003. This region was selected for the project because extensive gypsy moth defoliation occurred there over multiple years during the MODIS operational period. This RPC experiment is relevant to several nationally important mapping applications, including agricultural efficiency, coastal management, ecological forecasting, disaster management, and carbon management. In this experiment, MODIS data and VIIRS data simulated from MODIS were assessed for their ability to contribute broad, regional geospatial information on gypsy moth defoliation. Landsat and ASTER (Advanced Spaceborne Thermal Emission and Reflection Radiometer) data were used to assess the quality of gypsy moth defoliation mapping products derived from MODIS data and from simulated VIIRS data. The project focused on use of data from MODIS Terra as opposed to MODIS Aqua mainly because only MODIS Terra data was collected during 2000 and 2001-years with comparatively high amounts of gypsy moth defoliation within the study area. The project assessed the quality of VIIRS data simulation products. Hyperion data was employed to assess the quality of MODIS-based VIIRS simulation datasets using image correlation analysis techniques. The ART (Application Research Toolbox) software was used for data simulation. Correlation analysis between MODIS-simulated VIIRS data and Hyperion-simulated VIIRS data for red, NIR (near-infrared), and NDVI (Normalized Difference Vegetation Index) image data products collectively indicate that useful, effective VIIRS simulations can be produced using Hyperion and MODIS data sources. The r(exp 2) for red, NIR, and NDVI products were 0.56, 0.63, and 0.62, respectively, indicating a moderately high correlation between the 2 data sources. Temporal decorrelation from different data acquisition times and image misregistration may have lowered correlation results. The RPC experiment also generated MODIS-based time series data products using the TSPT (Time Series Product Tool) software. Time series of simulated VIIRS NDVI products were produced at approximately 400-meter resolution GSD (Ground Sampling Distance) at nadir for comparison to MODIS NDVI products at either 250- or 500-meter GSD. The project also computed MODIS (MOD02) NDMI (Normalized Difference Moisture Index) products at 500-meter GSD for comparison to NDVI-based products. For each year during 2000-2006, MODIS and VIIRS (simulated from MOD02) time series were computed during the peak gypsy moth defoliation time frame in the study area (approximately June 10 through July 27). Gypsy moth defoliation mapping products from simated VIIRS and MOD02 time series were produced using multiple methods, including image classification and change detection via image differencing. The latter enabled an automated defoliation detection product computed using percent change in maximum NDVI for a peak defoliation period during 2001 compared to maximum NDVI across the entire 2000-2006 time frame. Final gypsy moth defoliation mapping products were assessed for accuracy using randomly sampled locations found on available geospatial reference data (Landsat and ASTER data in conjunction with defoliation map data from the USFS). Extensive gypsy moth defoliation patches were evident on screen displays of multitemporal color composites derived from MODIS data and from simulated VIIRS vegetation index data. Such defoliation was particularly evident for 2001, although widespread denuded forests were also seen for 2000 and 2003. These visualizations were validated using aforementioned reference data. Defoliation patches were visible on displays of MODIS-based NDVI and NDMI data. The viewing of apparent defoliation patches on all of these products necessitated adoption of a specialized temporal data processing method (e.g., maximum NDVI during the peak defoliation time frame). The frequency of cloud cover necessitated this approach. Multitemporal simulated VIIRS and MODIS Terra data both produced effective general classifications of defoliated forest versus other land cover. For 2001, the MOD02-simulated VIIRS 400-meter NDVI classification produced a similar yet slightly lower overall accuracy (87.28 percent with 0.72 Kappa) than the MOD02 250-meter NDVI classification (88.44 percent with 0.75 Kappa). The MOD13 250-meter NDVI classification had a lower overall accuracy (79.13 percent) and a much lower Kappa (0.46). The report discusses accuracy assessment results in much more detail, comparing overall classification and individual class accuracy statistics for simulated VIIRS 400-meter NDVI, MOD02 250-meter NDVI, MOD02-500 meter NDVI, MOD13 250-meter NDVI, and MOD02 500-meter NDMI classifications. Automated defoliation detection products from simulated VIIRS and MOD02 data for 2001 also yielded similar, relatively high overall classification accuracy (85.55 percent for the VIIRS 400-meter NDVI versus 87.28 percent for the MOD02 250-meter NDVI). In contrast, the USFS aerial sketch map of gypsy moth defoliation showed a lower overall classification accuracy at 73.64 percent. The overall classification Kappa values were also similar for the VIIRS (approximately 0.67 Kappa) versus the MOD02 (approximately 0.72 Kappa) automated defoliation detection product, which were much higher than the values exhibited by the USFS sketch map product (overall Kappa of approximately 0.47). The report provides additional details on the accuracy of automated gypsy moth defoliation detection products compared with USFS sketch maps. The results suggest that VIIRS data can be effectively simulated from MODIS data and that VIIRS data will produce gypsy moth defoliation mapping products that are similar to MODIS-based products. The results of the RPC experiment indicate that VIIRS and MODIS data products have good potential for integration into the forest threat EWS. The accuracy assessment was performed only for 2001 because of time constraints and a relative scarcity of cloud-free Landsat and ASTER data for the peak defoliation period of the other years in the 2000-2006 time series. Additional work should be performed to assess the accuracy of gypsy moth defoliation detection products for additional years.The study area (mid-Appalachian highlands) and application (gypsy moth forest defoliation) are not necessarily representative of all forested regions and of all forest threat disturbance agents. Additional work should be performed on other inland and coastal regions as well as for other major forest threats.

  2. When is success not satisfying? Integrating regulatory focus and approach/avoidance motivation theories to explain the relation between core self-evaluation and job satisfaction.

    PubMed

    Ferris, D Lance; Johnson, Russell E; Rosen, Christopher C; Djurdjevic, Emilija; Chang, Chu-Hsiang Daisy; Tan, James A

    2013-03-01

    Integrating implications from regulatory focus and approach/avoidance motivation theories, we present a framework wherein motivational orientations toward positive (approach motivation orientation) or negative (avoidance motivation orientation) stimuli interact with workplace success to mediate the relation of core self-evaluation (CSE) with job satisfaction. Using data collected from supervisor-subordinate dyads (Sample 1) and time-lagged data (Sample 2), we found that the results from two studies indicated that the interaction of workplace success and avoidance motivation orientation mediated relations of CSE with job satisfaction. Although approach motivation orientation did not interact with workplace success, it did mediate the CSE-job satisfaction relation on its own. Implications for the CSE and approach/avoidance literatures are discussed.

  3. Historical reconstructions of California wildfires vary by data source

    USGS Publications Warehouse

    Syphard, Alexandra D.; Keeley, Jon E.

    2016-01-01

    Historical data are essential for understanding how fire activity responds to different drivers. It is important that the source of data is commensurate with the spatial and temporal scale of the question addressed, but fire history databases are derived from different sources with different restrictions. In California, a frequently used fire history dataset is the State of California Fire and Resource Assessment Program (FRAP) fire history database, which circumscribes fire perimeters at a relatively fine scale. It includes large fires on both state and federal lands but only covers fires that were mapped or had other spatially explicit data. A different database is the state and federal governments’ annual reports of all fires. They are more complete than the FRAP database but are only spatially explicit to the level of county (California Department of Forestry and Fire Protection – Cal Fire) or forest (United States Forest Service – USFS). We found substantial differences between the FRAP database and the annual summaries, with the largest and most consistent discrepancy being in fire frequency. The FRAP database missed the majority of fires and is thus a poor indicator of fire frequency or indicators of ignition sources. The FRAP database is also deficient in area burned, especially before 1950. Even in contemporary records, the huge number of smaller fires not included in the FRAP database account for substantial cumulative differences in area burned. Wildfires in California account for nearly half of the western United States fire suppression budget. Therefore, the conclusions about data discrepancies and the implications for fire research are of broad importance.

  4. A Derived Relations Analysis of Approach-Avoidance Conflict: Implications for the Behavioral Analysis of Human Anxiety

    ERIC Educational Resources Information Center

    Gannon, Steven; Roche, Bryan; Kanter, Jonathan W.; Forsyth, John P.; Linehan, Conor

    2011-01-01

    The current article reports two experiments designed to examine the effects of creating competing approach and avoidance response functions for 2 stimuli that participate in the same derived stimulus relation. Experiment 1 involved establishing each of 2 distinct members (i.e., B1 and D1) of the same 1-node equivalence relation (A-B-C-D) as a…

  5. Meta-Analysis of Land Use / Land Cover Change Factors in the Conterminous US and Prediction of Potential Working Timberlands in the US South from FIA Inventory Plots and NLCD Cover Maps

    NASA Astrophysics Data System (ADS)

    Jeuck, James A.

    This dissertation consists of research projects related to forest land use / land cover (LULC): (1) factors predicting LULC change and (2) methodology to predict particular forest use, or "potential working timberland" (PWT), from current forms of land data. The first project resulted in a published paper, a meta-analysis of 64 econometric models from 47 studies predicting forest land use changes. The response variables, representing some form of forest land change, were organized into four groups: forest conversion to agriculture (F2A), forestland to development (F2D), forestland to non-forested (F2NF) and undeveloped (including forestland) to developed (U2D) land. Over 250 independent econometric variables were identified, from 21 F2A models, 21 F2D models, 12 F2NF models, and 10 U2D models. These variables were organized into a hierarchy of 119 independent variable groups, 15 categories, and 4 econometric drivers suitable for conducting simple vote count statistics. Vote counts were summarized at the independent variable group level and formed into ratios estimating the predictive success of each variable group. Two ratio estimates were developed based on (1) proportion of times independent variables successfully achieved statistical significance (p ≤0.10), and (2) proportion of times independent variables successfully met the original researchers'expectations. In F2D models, popular independent variables such as population, income, and urban proximity often achieved statistical significance. In F2A models, popular independent variables such as forest and agricultural rents and costs, governmental programs, and site quality often achieved statistical significance. In U2D models, successful independent variables included urban rents and costs, zoning issues concerning forestland loss, site quality, urban proximity, population, and income. F2NF models high success variables were found to be agricultural rents, site quality, population, and income. This meta-analysis provides insight into the general success of econometric independent variables for future forest use or cover change research. The second part of this dissertation developed a method for predicting area estimates and spatial distribution of PWT in the US South. This technique determined land use from USFS Forest Inventory and Analysis (FIA) and land cover from the National Land Cover Database (NLCD). Three dependent variable forms (DV Forms) were derived from the FIA data: DV Form 1, timberland, other; DV Form 2, short timberland, tall timberland, agriculture, other; and DV Form 3, short hardwood (HW) timberland, tall HW timberland, short softwood (SW) timberland, tall SW timberland, agriculture, other. The prediction accuracy of each DV Form was investigated using both random forest model and logistic regression model specifications and data optimization techniques. Model verification employing a "leave-group-out" Monte Carlo simulation determined the selection of a stratified version of the random forest model using one-year NLCD observations with an overall accuracy of 0.53-0.94. The lower accuracy side of the range was when predictions were made from an aggregated NLCD land cover class "grass_shrub". The selected model specification was run using 2011 NLCD and the other predictor variables to produce three levels of timberland prediction and probability maps for the US South. Spatial masks removed areas unlikely to be working forests (protected and urbanized lands) resulting in PWT maps. The area of the resulting maps compared well with USFS area estimates and masked PWT maps and had an 8-11% reduction of the USFS timberland estimate for the US South compared to the DV Form. Change analysis of the 2011 NLCD to PWT showed (1) the majority of the short timberland came from NLCD grass_shrub; (2) the majority of NLCD grass_shrub predicted into tall timberland, and (3) NLCD grass_shrub was more strongly associated with timberland in the Coastal Plain. Resulting map products provide practical analytical tools for those interested in studying the area and distribution of PWT in the US South.

  6. In vivo regulation of the heme oxygenase-1 gene in humanized transgenic mice

    PubMed Central

    Kim, Junghyun; Zarjou, Abolfazl; Traylor, Amie M.; Bolisetty, Subhashini; Jaimes, Edgar A.; Hull, Travis D.; George, James F.; Mikhail, Fady M.; Agarwal, Anupam

    2012-01-01

    Heme oxygenase-1 (HO-1) catalyzes the rate-limiting step in heme degradation producing equimolar amounts of carbon monoxide, iron, and biliverdin. Induction of HO-1 is a beneficial response to tissue injury in diverse animal models of diseases including acute kidney injury. In vitro analysis has shown that the human HO-1 gene is transcriptionally regulated by changes in chromatin conformation but whether such control occurs in vivo is not known. To enable such analysis, we generated transgenic mice, harboring an 87-kb bacterial artificial chromosome expressing human HO-1 mRNA and protein and bred these mice with HO-1 knockout mice to generate humanized BAC transgenic mice. This successfully rescued the phenotype of the knockout mice including reduced birth rates, tissue iron overload, splenomegaly, anemia, leukocytosis, dendritic cell abnormalities and survival after acute kidney injury induced by rhabdomyolysis or cisplatin nephrotoxicity. Transcription factors such as USF1/2, JunB, Sp1, and CTCF were found to associate with regulatory regions of the human HO-1 gene in the kidney following rhabdomyolysis. Chromosome Conformation Capture and ChIP-loop assays confirmed this in the formation of chromatin looping in vivo. Thus, these bacterial artificial chromosome humanized HO-1 mice are a valuable model to study the human HO-1 gene providing insight to the in vivo architecture of the gene in acute kidney injury and other diseases. PMID:22495295

  7. Response of Florida shelf ecosystems to climate change: from macro to micro scales

    USGS Publications Warehouse

    Robbins, Lisa; Raabe, Ellen

    2010-01-01

    U.S. Geological Survey (USGS) research in St. Petersburg, Fla., is focusing attention on marine environments of the Florida shelf at three levels, from regional to estuarine to the individual organism. The USGS is partnering on this project with the Florida Department of Agriculture and Consumer Services (DACS), National Oceanic and Atmospheric Administration (NOAA), and the University of South Florida (USF) in marine studies. The specific goals of these combined efforts are an improved understanding of the effects of ocean acidification on regional carbonate processes, changes in individual estuaries, and organism-level response. This understanding will assist in developing appropriate Federal, State, and local management responses to climate change in coastal areas.

  8. Utilizing multi-sensor fire detections to map fires in the United States

    USGS Publications Warehouse

    Howard, Stephen M.; Picotte, Joshua J.; Coan, Michael

    2014-01-01

    In 2006, the Monitoring Trends in Burn Severity (MTBS) project began a cooperative effort between the US Forest Service (USFS) and the U.S.Geological Survey (USGS) to map and assess burn severity all large fires that have occurred in the United States since 1984. Using Landsat imagery, MTBS is mandated to map wildfire and prescribed fire that meet specific size criteria: greater than 1000 acres in the west and 500 acres in the east, regardless of ownership. Relying mostly on federal and state fire occurrence records, over 15,300 individual fires have been mapped. While mapping recorded fires, an additional 2,700 “unknown” or undocumented fires were discovered and assessed. It has become apparent that there are perhaps thousands of undocumented fires in the US that are yet to be mapped. Fire occurrence records alone are inadequate if MTBS is to provide a comprehensive accounting of fire across the US. Additionally, the sheer number of fires to assess has overwhelmed current manual procedures. To address these problems, the National Aeronautics and Space Administration (NASA) Applied Sciences Program is helping to fund the efforts of the USGS and its MTBS partners (USFS, National Park Service) to develop, and implement a system to automatically identify fires using satellite data. In near real time, USGS will combine active fire satellite detections from MODIS, AVHRR and GOES satellites with Landsat acquisitions. Newly acquired Landsat imagery will be routinely scanned to identify freshly burned area pixels, derive an initial perimeter and tag the burned area with the satellite date and time of detection. Landsat imagery from the early archive will be scanned to identify undocumented fires. Additional automated fire assessment processes will be developed. The USGS will develop these processes using open source software packages in order to provide freely available tools to local land managers providing them with the capability to assess fires at the local level.

  9. Numerical modeling of laboratory-scale surface-to-crown fire transition

    NASA Astrophysics Data System (ADS)

    Castle, Drew Clayton

    Understanding the conditions leading to the transition of fire spread from a surface fuel to an elevated (crown) fuel is critical to effective fire risk assessment and management. Surface fires that successfully transition to crown fires can be very difficult to suppress, potentially leading to damages in the natural and built environments. This is relevant to chaparral shrub lands which are common throughout parts of the Southwest U.S. and represent a significant part of the wildland urban interface. The ability of the Wildland-Urban Interface Fire Dynamic Simulator (WFDS) to model surface-to-crown fire transition was evaluated through comparison to laboratory experiments. The WFDS model is being developed by the U.S. Forest Service (USFS) and the National Institute of Standards and Technology. The experiments were conducted at the USFS Forest Fire Laboratory in Riverside, California. The experiments measured the ignition of chamise (Adenostoma fasciculatum) crown fuel held above a surface fire spreading through excelsior fuel. Cases with different crown fuel bulk densities, crown fuel base heights, and imposed wind speeds were considered. Cold-flow simulations yielded wind speed profiles that closely matched the experimental measurements. Next, fire simulations with only the surface fuel were conducted to verify the rate of spread while factors such as substrate properties were varied. Finally, simulations with both a surface fuel and a crown fuel were completed. Examination of specific surface fire characteristics (rate of spread, flame angle, etc.) and the corresponding experimental surface fire behavior provided a basis for comparison of the factors most responsible for transition from a surface fire to the raised fuel ignition. The rate of spread was determined by tracking the flame in the Smokeview animations using a tool developed for tracking an actual flame in a video. WFDS simulations produced results in both surface fire spread and raised fuel bed ignition which closely matched the trends reported in the laboratory experiments.

  10. Utilizing Multi-Sensor Fire Detections to Map Fires in the United States

    NASA Astrophysics Data System (ADS)

    Howard, S. M.; Picotte, J. J.; Coan, M. J.

    2014-11-01

    In 2006, the Monitoring Trends in Burn Severity (MTBS) project began a cooperative effort between the US Forest Service (USFS) and the U.S.Geological Survey (USGS) to map and assess burn severity all large fires that have occurred in the United States since 1984. Using Landsat imagery, MTBS is mandated to map wildfire and prescribed fire that meet specific size criteria: greater than 1000 acres in the west and 500 acres in the east, regardless of ownership. Relying mostly on federal and state fire occurrence records, over 15,300 individual fires have been mapped. While mapping recorded fires, an additional 2,700 "unknown" or undocumented fires were discovered and assessed. It has become apparent that there are perhaps thousands of undocumented fires in the US that are yet to be mapped. Fire occurrence records alone are inadequate if MTBS is to provide a comprehensive accounting of fire across the US. Additionally, the sheer number of fires to assess has overwhelmed current manual procedures. To address these problems, the National Aeronautics and Space Administration (NASA) Applied Sciences Program is helping to fund the efforts of the USGS and its MTBS partners (USFS, National Park Service) to develop, and implement a system to automatically identify fires using satellite data. In near real time, USGS will combine active fire satellite detections from MODIS, AVHRR and GOES satellites with Landsat acquisitions. Newly acquired Landsat imagery will be routinely scanned to identify freshly burned area pixels, derive an initial perimeter and tag the burned area with the satellite date and time of detection. Landsat imagery from the early archive will be scanned to identify undocumented fires. Additional automated fire assessment processes will be developed. The USGS will develop these processes using open source software packages in order to provide freely available tools to local land managers providing them with the capability to assess fires at the local level.

  11. Job Enrichment: Evaluation with Implications for Air Force Job Redesign. Interim Report, 1 January 1975-30 April 1977.

    ERIC Educational Resources Information Center

    Watson, Thomas W.; Zumbro, Patrick A.

    The main text of this report consists of a review and evaluation of job enrichment as an approach to job redesign, with implications for Air Force research and application. In addition, two appendixes are included: the first, a supplemental historical discussion; the second, a ninety-six-item annotated bibliography. Specific objectives are to…

  12. Implications of DSM-5 for Health Care Organizations and Mental Health Policy.

    PubMed

    Castillo, Richard J; Guo, Kristina L

    2016-01-01

    The American Psychiatric Association (APA) has made major changes in the way mental illness is conceptualized, assessed, and diagnosed in its new diagnostic manual, the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), published in 2013, and has far reaching implications for health care organizations and mental health policy. This paper reviews the four new principles in DSM-5: 1) A spectrum (also called "dimensional") approach to the definition of mental illness; 2) recognition of the role played by environmental risk factors related to stress and trauma in predisposing, precipitating, and perpetuating mental illness; 3) cultural relativism in diagnosis and treatment of mental illness; and 4) recognizing the adverse effects of psychiatric medications on patients. Each of these four principles will be addressed in detail. In addition, four major implications for health care organizations and mental health policy are identified as: 1) prevention; 2) client-centered psychiatry; 3) mental health workers retraining; and 4) medical insurance reform. We conclude that DSM- 5's new approach to diagnosis and treatment of mental illness will have profound implications for health care organizations and mental health policy, indicating a greater emphasis on prevention and cure rather than long-term management of symptoms.

  13. Characterizing Wildfire Regimes and Risk in the USA

    NASA Astrophysics Data System (ADS)

    Malamud, B. D.; Millington, J. D.; Perry, G. L.

    2004-12-01

    Over the last decade, high profile wildfires have resulted in numerous fatalities and loss of infrastructure. Wildfires also have a significant impact on climate and ecosystems, with recent authors emphasizing the need for regional-level examinations of wildfire-regime dynamics and change, and the factors driving them. With implications for hazard management, climate studies, and ecosystem research, there is therefore significant interest in appropriate analysis of historical wildfire databases. Insightful studies using wildfire database statistics exist, but are often hampered by the low spatial and/or temporal resolution of their datasets. In this paper, we use a high-resolution dataset consisting of 88,855 USFS wildfires over the time period 1970--2000, and consider wildfire occurrence across the conterminous USA as a function of ecoregion (land units classified by climate, vegetation, and topography), ignition source (anthropogenic vs. lightning), and decade (1970--1979, 1980--1989, 1990--1999). We find that for the conterminous USA (a) wildfires exhibit robust frequency-area power-law behavior in 17 different ecoregions, (b) normalized power-law exponents may be used to compare the scaling of wildfire burned areas between regions, (c) power-law exponents change systematically from east to west, (d) wildfires in 75% of the conterminous USA (particularly the east) have higher power-law exponents for anthropogenic vs. lightning ignition sources, and (e) recurrence intervals for wildfires of a given burned area or larger for each ecoregion can be assessed, allowing for the classification of wildfire regimes for probabilistic hazard estimation in the same vein as is now used for earthquakes. By examining wildfire statistics in a spatially and temporally explicit manner, we are able to present resultant wildfire regime summary statistics and conclusions, along with a probabilistic hazard assessment of wildfire risk at the ecoregion division level across the conterminous USA.

  14. Harmonic regression of Landsat time series for modeling attributes from national forest inventory data

    NASA Astrophysics Data System (ADS)

    Wilson, Barry T.; Knight, Joseph F.; McRoberts, Ronald E.

    2018-03-01

    Imagery from the Landsat Program has been used frequently as a source of auxiliary data for modeling land cover, as well as a variety of attributes associated with tree cover. With ready access to all scenes in the archive since 2008 due to the USGS Landsat Data Policy, new approaches to deriving such auxiliary data from dense Landsat time series are required. Several methods have previously been developed for use with finer temporal resolution imagery (e.g. AVHRR and MODIS), including image compositing and harmonic regression using Fourier series. The manuscript presents a study, using Minnesota, USA during the years 2009-2013 as the study area and timeframe. The study examined the relative predictive power of land cover models, in particular those related to tree cover, using predictor variables based solely on composite imagery versus those using estimated harmonic regression coefficients. The study used two common non-parametric modeling approaches (i.e. k-nearest neighbors and random forests) for fitting classification and regression models of multiple attributes measured on USFS Forest Inventory and Analysis plots using all available Landsat imagery for the study area and timeframe. The estimated Fourier coefficients developed by harmonic regression of tasseled cap transformation time series data were shown to be correlated with land cover, including tree cover. Regression models using estimated Fourier coefficients as predictor variables showed a two- to threefold increase in explained variance for a small set of continuous response variables, relative to comparable models using monthly image composites. Similarly, the overall accuracies of classification models using the estimated Fourier coefficients were approximately 10-20 percentage points higher than the models using the image composites, with corresponding individual class accuracies between six and 45 percentage points higher.

  15. Smokey the Bear Toy floating in ISS Hatchway

    NASA Image and Video Library

    2012-08-03

    ISS032-E-011678 (3 Aug. 2012) --- Smokey Bear floats freely near a hatchway on the International Space Station. On May 15, 2012, Smokey traveled aboard the Soyuz spacecraft with NASA astronaut Joe Acaba and Russian cosmonauts Gennady Padalka and Sergei Revin to the space station. As a recognized symbol for wildland fire prevention, his presence on the orbiting complex also highlights the many areas of active space station research related to Earth observations, plant growth and combustion and materials sciences, as well as existing spinoff technologies in these areas. NASA, the U.S. Forest Service (USFS) and the Texas Forest Service are teaming up to celebrate Smokey's 68th birthday Aug. 9 at NASA's Johnson Space Center in Houston.

  16. Satellite Ka-band propagation measurements in Florida

    NASA Technical Reports Server (NTRS)

    Helmken, Henry; Henning, Rudolf

    1995-01-01

    Commercial growth of interactive, high data rate communication systems is expected to focus on the use of the Ka-band (20/30 GHz) radio spectrum. The ability to form narrow spot beams and the attendant small diameter antennas are attractive features to designers of mobile aeronautical and ground based satellite communication systems. However, Ka-band is strongly affected by weather, particularly rain, and hence systems designs may require a significant link margin for reliable operations. Perhaps the most stressing area in North America, weatherwise, is the Florida sub-tropical climatic region. As part of the NASA Advanced Communications Technology Satellite (ACTS) propagation measurements program, beacon and radiometer data have been recorded since December 1993 at the University of South Florida (USF), Tampa, Florida.

  17. A genomewide survey of basic helix–loop–helix factors in Drosophila

    PubMed Central

    Moore, Adrian W.; Barbel, Sandra; Jan, Lily Yeh; Jan, Yuh Nung

    2000-01-01

    The basic helix–loop–helix (bHLH) transcription factors play important roles in the specification of tissue type during the development of animals. We have used the information contained in the recently published genomic sequence of Drosophila melanogaster to identify 12 additional bHLH proteins. By sequence analysis we have assigned these proteins to families defined by Atonal, Hairy-Enhancer of Split, Hand, p48, Mesp, MYC/USF, and the bHLH-Per, Arnt, Sim (PAS) domain. In addition, one single protein represents a unique family of bHLH proteins. mRNA in situ analysis demonstrates that the genes encoding these proteins are expressed in several tissue types but are particularly concentrated in the developing nervous system and mesoderm. PMID:10973473

  18. High-Resolution Forest Carbon Monitoring and Modeling: Continued Prototype Development and Deployment Across The Tri-state Area (MD, PA, DE), USA

    NASA Astrophysics Data System (ADS)

    Hurtt, G. C.; Birdsey, R.; Campbell, E.; Dolan, K. A.; Dubayah, R.; Escobar, V. M.; Finley, A. O.; Flanagan, S.; Huang, W.; Johnson, K.; Lister, A.; ONeil-Dunne, J.; Sepulveda Carlo, E.; Zhao, M.

    2017-12-01

    Local, national and international programs have increasing need for precise and accurate estimates of forest carbon and structure to support greenhouse gas reduction plans, climate initiatives, and other international climate treaty frameworks. In 2010 Congress directed NASA to initiate research towards the development of Carbon Monitoring Systems (CMS). In response, our team has worked to develop a robust, replicable framework to produce maps of high-resolution carbon stocks and future carbon sequestration potential. High-resolution (30m) maps of carbon stocks and uncertainty were produced by linking national 1m-resolution imagery and existing wall-to-wall airborne lidar to spatially explicit in-situ field observations such as the USFS Forest Inventory and Analysis (FIA) network. These same data, characterizing forest extent and vertical structure, were used to drive a prognostic ecosystem model to predict carbon fluxes and carbon sequestration potential at unprecedented spatial resolution and scale (90m), more than 100,000 times the spatial resolution of standard global models. Through project development, the domain of this research has expanded from two counties in MD (2,181 km2), to the entire state (32,133 km2), to the tri-state region of MD, PA, and DE (157,868 km2), covering forests in four major USDA ecological providences (Eastern Broadleaf, Northeastern Mixed, Outer Coastal Plain, and Central Appalachian). Across the region, we estimate 694 Tg C (14 DE, 113 MD, 567 PA) in above ground biomass, and estimate a carbon sequestration potential more than twice that amount. Empirical biomass products enhance existing approaches though high resolution accounting for trees outside traditional forest maps. Modeling products move beyond traditional MRV, and map future afforestation and reforestation potential for carbon at local actionable spatial scales. These products are relevant to multiple stakeholder needs in the region as discussed through the Tri-sate Working Group, and are actively being used to inform the state of MD's Greenhouse Gas Reduction Act. The approach is scalable, and provides a protoype framework for application in other domains and for future spaceborne lidar missions.

  19. Contribution of National near Real Time MODIS Forest Maximum Percentage NDVI Change Products to the U.S. ForWarn System

    NASA Technical Reports Server (NTRS)

    Spruce, Joseph P.; Hargrove, William; Gasser, Gerald; Smoot, James; Kuper, Philip D.

    2012-01-01

    This presentation reviews the development, integration, and testing of Near Real Time (NRT) MODIS forest % maximum NDVI change products resident to the USDA Forest Service (USFS) ForWarn System. ForWarn is an Early Warning System (EWS) tool for detection and tracking of regionally evident forest change, which includes the U.S. Forest Change Assessment Viewer (FCAV) (a publically available on-line geospatial data viewer for visualizing and assessing the context of this apparent forest change). NASA Stennis Space Center (SSC) is working collaboratively with the USFS, ORNL, and USGS to contribute MODIS forest change products to ForWarn. These change products compare current NDVI derived from expedited eMODIS data, to historical NDVI products derived from MODIS MOD13 data. A new suite of forest change products are computed every 8 days and posted to the ForWarn system; this includes three different forest change products computed using three different historical baselines: 1) previous year; 2) previous three years; and 3) all previous years in the MODIS record going back to 2000. The change product inputs are maximum value NDVI that are composited across a 24 day interval and refreshed every 8 days so that resulting images for the conterminous U.S. are predominantly cloud-free yet still retain temporally relevant fresh information on changes in forest canopy greenness. These forest change products are computed at the native nominal resolution of the input reflectance bands at 231.66 meters, which equates to approx 5.4 hectares or 13.3 acres per pixel. The Time Series Product Tool, a MATLAB-based software package developed at NASA SSC, is used to temporally process, fuse, reduce noise, interpolate data voids, and re-aggregate the historical NDVI into 24 day composites, and then custom MATLAB scripts are used to temporally process the eMODIS NDVIs so that they are in synch with the historical NDVI products. Prior to posting, an in-house snow mask classification product is computed for the current compositing period and integrated into the change images to account for snow related NDVI drops. The supplemental snow classification product was needed because other available QA cloud/snow mask typically underestimates snow cover. MODIS true and false color composites were also computed from eMODIS reflectance data and the true color RGBs are also posted on ForWarn?s FCAV; this data is used for assessing apparent occasional quality issues on the change products due to residual unmasked cloud cover. New forest change products are posted with typical latencies of 1-2 days after the last input eMODIS data collection date for a given 24 day compositing period.

  20. Psychological Contracts and Their Implications for Commitment: A Feature-Based Approach

    ERIC Educational Resources Information Center

    McInnis, Kate J.; Meyer, John P.; Feldman, Susan

    2009-01-01

    Two studies were conducted to examine the link between employee perceptions of the psychological contract and their affective and normative commitments to the organization. The authors adapt a new approach to the study of psychological contracts by developing a generalizable measure of "contract features" (e.g., scope; time frame). In Study 1…

  1. Reconstructive Memory: A Non-Traditional Approach to Assessing Young Children's Intelligence.

    ERIC Educational Resources Information Center

    Cocking, Rodney R.; And Others

    Implications are discussed for new instrument development by way of a methodological study which used a task allowing one to focus upon: (1) a non-verbal approach; (2) memory functions; (3) a variety of mnemonics that children use in information retrieval; and (4) a non-traditional procedure supported by psychological and developmental research. A…

  2. Privacy and social implications of distinct sensing approaches to implementing smart homes for older adults.

    PubMed

    Demiris, George

    2009-01-01

    Two distinct approaches to smart home design, namely Distributed Direct Sensing (DDS) and Infrastructure Mediated Sensing (IMS), have distinguishing features and implications resulting from their implementation. These two distinct smart home approaches have not been directly compared pertaining to their technical performance or their acceptance by the end users. It is also unclear what the perceived privacy and obtrusiveness concerns are when it comes to the implementation of these two different approaches in homes. The study presented here aimed to evaluate acceptance of these two sensing approaches by older adults and assess the perceived privacy and obtrusiveness concerns and ultimately define their social implications.

  3. Perceiving outgroup members as unresponsive: implications for approach-related emotions, intentions, and behavior.

    PubMed

    Butz, David A; Plant, E Ashby

    2006-12-01

    In 2 studies, the authors investigated the determinants of anger and approach-related intentions and behavior toward outgroup members in interracial interactions. In Study 1, White and Black participants who were led to believe that their interracial interaction partner was not open to an upcoming interaction reported heightened anger and approach-related intentions concerning the interaction, including viewing their partner as hostile, intending to ask sensitive race-relevant questions during the interaction, and planning to blame the partner if the interaction went poorly. Results of Study 2 showed that White participants who received negative feedback about their Black partner's openness to interracial interactions behaved in a hostile manner toward their interaction partner. The findings are discussed in terms of their implications for the quality of interracial interactions. (c) 2006 APA, all rights reserved.

  4. Upper Stage Flight Experiment 10K Engine Design and Test Results

    NASA Technical Reports Server (NTRS)

    Ross, R.; Morgan, D.; Crockett, D.; Martinez, L.; Anderson, W.; McNeal, C.

    2000-01-01

    A 10,000 lbf thrust chamber was developed for the Upper Stage Flight Experiment (USFE). This thrust chamber uses hydrogen peroxide/JP-8 oxidizer/fuel combination. The thrust chamber comprises an oxidizer dome and manifold, catalyst bed assembly, fuel injector, and chamber/nozzle assembly. Testing of the engine was done at NASA's Stennis Space Center (SSC) to verify its performance and life for future upper stage or Reusable Launch Vehicle applications. Various combinations of silver screen catalyst beds, fuel injectors, and combustion chambers were tested. Results of the tests showed high C* efficiencies (97% - 100%) and vacuum specific impulses of 275 - 298 seconds. With fuel film cooling, heating rates were low enough that the silica/quartz phenolic throat experienced minimal erosion. Mission derived requirements were met, along with a perfect safety record.

  5. Relative toxicity of pyrolysis products of some materials used in home furnishings

    NASA Technical Reports Server (NTRS)

    Hilado, C. J.; Furst, A.

    1976-01-01

    Seventy samples of cushioning and upholstery materials used in home furnishings were evaluated for relative toxicity by means of the USF/NASA toxicity screening test. The materials were variably toxic under pyrolysis conditions, and this test appeared suitable for discriminating among them on the bases of time to incapacitation and time to death. The addition of fire retardants to these materials to comply with flammability regulations either had no significant effect on toxicity, or resulted in a reduction in relative toxicity. The modification of materials to comply with California upholstered furniture flammability regulations appears to have resulted in desirable limitations on toxicity. Fifty percent of the 70 materials tested caused incapacitation earlier than did the materials in compliance, and 30 percent caused death earlier.

  6. Dataset of timberland variables used to assess forest conditions in two Southeastern United States' fuelsheds

    DOE PAGES

    Parish, Esther S.; Dale, Virginia H.; Tobin, Emma; ...

    2017-05-27

    The data presented in this article are related to the research article entitled “How is wood-based pellet production affecting forest conditions in the southeastern United States?” (Dale et al., 2017). This article describes how United States Forest Service (USFS) Forest Inventory and Analysis (FIA) data from multiple state inventories were aggregated and used to extract ten annual timberland variables for trend analysis in two case study bioenergy fuelshed areas. This dataset is made publically available to enable critical or extended analyses of changes in forest conditions, either for the fuelshed areas supplying the ports of Savannah, Georgia and Chesapeake, Virginia,more » or for other southeastern US forested areas contributing biomass to the export wood pellet industry.« less

  7. Before-and-After LIDAR Images from 2014 King Fire in El Dorado National Forest

    NASA Image and Video Library

    2015-04-09

    New maps of two recent California megafires that combine unique data sets from the U.S. Forest Service and NASA's Jet Propulsion Laboratory in Pasadena, California, are answering some of the urgent questions that follow a huge wildfire. These before-and-after USFS LIght Detection And Ranging (LIDAR) images from the 2014 King fire region in El Dorado National Forest, California are among new maps. They show a small section of the Rubicon River drainage basin, where fire damage was severe. Blue indicates ground level; lighter colors are higher. A road -- bordered by dense trees in the before image at left -- and part of a bridge are in the center, with the bridge appearing green. http://photojournal.jpl.nasa.gov/catalog/PIA19360

  8. Dataset of timberland variables used to assess forest conditions in two Southeastern United States' fuelsheds

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Parish, Esther S.; Dale, Virginia H.; Tobin, Emma

    The data presented in this article are related to the research article entitled “How is wood-based pellet production affecting forest conditions in the southeastern United States?” (Dale et al., 2017). This article describes how United States Forest Service (USFS) Forest Inventory and Analysis (FIA) data from multiple state inventories were aggregated and used to extract ten annual timberland variables for trend analysis in two case study bioenergy fuelshed areas. This dataset is made publically available to enable critical or extended analyses of changes in forest conditions, either for the fuelshed areas supplying the ports of Savannah, Georgia and Chesapeake, Virginia,more » or for other southeastern US forested areas contributing biomass to the export wood pellet industry.« less

  9. Stratton Sagebrush Hydrology Study Area: An annotated bibliography of research conducted 1968-1990

    USGS Publications Warehouse

    Burgess, Leah M.; Schoenecker, Kathryn A.

    2004-01-01

    This annotated bibliography provides an overview of research projects conducted on the Stratton Sagebrush Hydrology Study Area (Stratton) since its designation as such in 1967. Sources include the Rocky Mountain Forest and Range Experiment Station records storage room, Laramie, Wyoming, the USGS and USFS online reference libraries, and scientific journal databases at the University of Wyoming and Colorado State University. This annotated bibliography summarizes publications from research conducted at Stratton during the prime of its tenure as a research lab from 1968 to 1990. In addition, an appendix is included that catalogues all data on file at the Rocky Mountain Forest and Range Experiment Station in Laramie, Wyoming. Each file folder was searched and its contents recorded here for the researcher seeking original data sets, charts, photographs and records.

  10. Apprentissage de l'expression orale en autonomie. Implications de l'approche fonctionelle (Learning Oral Expression in Independent Study. Implications of the Functional Approach). Melanges pedagogiques.

    ERIC Educational Resources Information Center

    Abe, D.; And Others

    Within the CRAPEL autonomous learning scheme, modular material is being developed for communicative oral expression. The purpose of this material is twofold: (1) to enable the learner to define his or her own needs in communicative terms, that is, to analyse a situation in terms of communicative acts needed in a given situation, the relationships…

  11. Interim report on the scientific investigations in the Animas River watershed, Colorado to facilitate remediation decisions by the U.S. Bureau of Land Management and the U.S. Forest Service, March 29, 2000 meeting, Denver, Colorado

    USGS Publications Warehouse

    ,

    2000-01-01

    INTRODUCTION The joint U.S. Department of the Interior and U.S. Department of Agriculture Abandoned Mine Lands Initiative (AMLI) was developed as a collaborative effort between the Federal land management agencies (FLMA, that is the U.S. Bureau of Land Management and the U.S. Forest Service) and the U.S. Geological Survey (USGS) in 1996. The stated goal of the AML Initiative was to develop a strategy for gathering and communicating the scientific information needed to develop effective and cost-efficient remediation of abandoned mines within the framework of a watershed. Four primary objectives of the AMLI are to: 1. Provide the scientific information needed (in the short-term) by the FLMAs to make decisions related to the design and implementation of cleanup actions, 2. Develop a multi-disciplined, multi-division approach that integrates geologic, hydrologic, geochemical and ecological information into a knowledge base for sound decision making, 3. Transfer technologies developed within the scientific programs of the USGS to the field and demonstrate their suitability to solve real, practical problems, and 4. Establish working relationships among involved members of land management and regulatory agencies within the framework of a watershed approach to the cleanup of abandoned mines. Long-term process-based research, including development of analytical tools, is recognized as being critical to the long-term success in remediating watersheds impacted by historical mining activities (AML 5-year plan, http://amli.usgs.gov/amli). In a meeting of Federal agencies (U.S. Bureau of Land Management [BLM], U.S. Bureau of Reclamation [BOR], U.S. National Park Service [NPS], U.S. Forest Service [USFS], the U.S. Environmental Protection Agency [EPA], the U.S. Fish and Wildlife Service [F&WS]), and State agencies (Colorado Division of Public Health and Environment, Colorado Division of Mines and Geology), several watersheds were examined within the state whose water quality was presumed to be impacted by historical mining activities. The Animas River watershed (fig. 1) was selected by the State and Federal agencies as one of two watersheds in the U.S. to be studied in detail by the USGS in the AML Initiative. Beginning in October 1997, each of the four Divisions of the USGS (Water Resources, Geologic, Biological Resources, and National Mapping) initiated a collaborative integrated science study of the watershed. Funds were provided from USGS base funding to each of the four Divisions in response to the priorities set by Congressional action and within the flexibility provided by the budgetary framework funding individual research programs. The AML Initiative provides for a five-year focused scientific effort in the two watersheds with final synthesis of the scientific results from each to be published in 2001. Publications are released on the AML web site on a regular basis (http://amli.usgs.gov/amli). On March 29, 2000, the USGS hosted a meeting for the BLM and USFS to discuss remediation options that were under consideration for the summer of 2000. The purpose of this report is to provide an overview of the scientific rational provided by the USGS to meet objective one above, and to summarize our preliminary interpretations of our data. Additional information from sites on private lands have been collected by the State of Colorado, EPA, and the ARSG. Unfortunately, these data have not been fully supplied to the USGS so our conclusions are based only upon our data. These interpretations provide science-based constraints on possible remediation options to be considered by the FLMA, the State, and local property owners in the Animas River watershed. The report is presented in outline format to facilitate discussion of remediation options at the March 29, 2000 meeting. Not all historical mining sites within the watershed are on public lands. This should not be construed to be a final report of the USGS

  12. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Caly, Leon; Kassouf, Vicki T.; Moseley, Gregory W.

    Nuclear import of the accessory protein Vpr is central to infection by human immunodeficiency virus (HIV). We previously identified the Vpr F72L mutation in a HIV-infected, long-term non-progressor, showing that it resulted in reduced Vpr nuclear accumulation and altered cytoplasmic localisation. Here we demonstrate for the first time that the effects of nuclear accumulation of the F72L mutation are due to impairment of microtubule-dependent-enhancement of Vpr nuclear import. We use high resolution imaging approaches including fluorescence recovery after photobleaching and other approaches to document interaction between Vpr and the dynein light chain protein, DYNLT1, and impaired interaction of the F72Lmore » mutant with DYNLT1. The results implicate MTs/DYNLT1 as drivers of Vpr nuclear import and HIV infection, with important therapeutic implications. - Highlights: • HIV-1 Vpr utilizes the microtubule network to traffic towards the nucleus. • Mechanism relies on interaction between Vpr and dynein light chain protein DYNLT1. • Long-term non-progressor derived mutation (F72L) impairs this interaction. • Key residues in the vicinity of F72 contribute to interaction with DYNLT1.« less

  13. Spatial geologic data model for the Gunnison, Grand Mesa, Uncompahgre National Forests mineral assessment area, southwestern Colorado and digital data for the Leadville, Montrose, Durango, and Colorado parts of the Grand Junction, Moab, and Cortez 1 degree x 2 degrees geologic maps

    USGS Publications Warehouse

    Day, W.C.; Green, G.N.; Knepper, D.H.; Phillips, R.C.

    1999-01-01

    The digital geologic and geographic information system (GIS) data presented here were prepared to aid in Grand Mesa, Uncompahgre, Gunnison National Forest (GMUG) mineral resource assessment Project studies by the U.S. Geological Survey Mineral Resource Program. The goals of the GMUG Project is to provide mineral resource data and an assessment for undiscovered mineral resources in U.S. Forest Service (USFS) and Bureau of Land Management (BLM) lands in southwestern Colorado. The Project area covers a large region in southwestern Colorado that is bounded by latitudes 37o 45’ to 39o 30’ north and longitudes 106o to 109o west. The study area is covered by all or parts of six 1o x2o topographic and quadrangle geologic maps, which include geologic maps for the Leadville (Tweto and others, 1978), Montrose (Tweto and others, 1976), Durango (Steven and others, 1974), Grand Junction (Cashion, 1973), Moab (Williams, 1976), and Cortez (Haynes and others, 1972) quadrangles. These geologic maps were used inasmuch as a complete remapping and compilation effort for this study area was beyond the scope of the Project.

  14. Introduction to the Special Series: Current Directions for Measuring Parenting Constructs to Inform Prevention Science.

    PubMed

    Lindhiem, Oliver; Shaffer, Anne

    2017-04-01

    Parenting behaviors are multifaceted and dynamic and therefore challenging to quantify. Measurement methods have critical implications for study results, particularly for prevention trials designed to modify parenting behaviors. Although multiple approaches can complement one another and contribute to a more complete understanding of prevention trials, the assumptions and implications of each approach are not always clearly addressed. Greater attention to the measurement of complex constructs such as parenting is needed to advance the field of prevention science. This series examines the challenges of measuring changes in parenting behaviors in the context of prevention trials. All manuscripts in the special series address measurement issues and make practical recommendations for prevention researchers. Manuscripts in this special series include (1) empirical studies that demonstrate novel measurement approaches, (2) re-analyses of prevention trial outcome data directly comparing and contrasting two or more methods, and (3) a statistical primer and practical guide to analyzing proportion data.

  15. Assessing Threats of School Violence: Implications for Counselors

    ERIC Educational Resources Information Center

    Daniels, Jeffrey A.

    2002-01-01

    The author describes important considerations when assessing students' threats made at schools. In a recent article, M. Reddy et al. (2001) presented 4 approaches to assessing the risk of school violence. They submitted important issues and problems with 3 commonly used approaches and suggested a 4th approach as an alternative. Implications for…

  16. Anger is an approach-related affect: evidence and implications.

    PubMed

    Carver, Charles S; Harmon-Jones, Eddie

    2009-03-01

    The authors review a range of evidence concerning the motivational underpinnings of anger as an affect, with particular reference to the relationship between anger and anxiety or fear. The evidence supports the view that anger relates to an appetitive or approach motivational system, whereas anxiety relates to an aversive or avoidance motivational system. This evidence appears to have 2 implications. One implication concerns the nature of anterior cortical asymmetry effects. The evidence suggests that such asymmetry reflects direction of motivational engagement (approach vs. withdrawal) rather than affective valence. The other implication concerns the idea that affects form a purely positive dimension and a purely negative dimension, which reflect the operation of appetitive and aversive motivational systems, respectively. The evidence reviewed does not support that view. The evidence is, however, consistent with a discrete-emotions view (which does not rely on dimensionality) and with an alternative dimensional approach. (c) 2009 APA, all rights reserved.

  17. Effects of climate change on ecological disturbance in the Northern Rockies Region [Chapter 8

    USGS Publications Warehouse

    Loehman, Rachel A.; Bentz, Barbara J.; DeNitto, Gregg A.; Keane, Robert E.; Manning, Mary E.; Duncan, Jacob P.; Egan, Joel M.; Jackson, Marcus B.; Kegley, Sandra; Lockman, I. Blakey; Pearson, Dean E.; Powell, James A.; Shelly, Steve; Steed, Brytten E.; Zambino, Paul J.

    2018-01-01

    This chapter describes the ecology of important disturbance regimes in the Forest Service, U.S. Department of Agriculture (USFS) Northern Region and the Greater Yellowstone Area, hereafter called the Northern Rockies region, and potential shifts in these regimes as a consequence of observed and projected climate change. The term disturbance regime describes the general temporal and spatial characteristics of a disturbance agent - insect, disease, fire, weather, even human activity - and the effects of that agent on the landscape (table 8.1). More specifically, a disturbance regime is the cumulative effect of multiple disturbance events over space and time (Keane 2013). Disturbances disrupt an ecosystem, community, or population structure and change elements of the biological environment, physical environment, or both (White and Pickett 1985). The resulting shifting mosaic of diverse ecological patterns and structures in turn affects future patterns of disturbance, in a reciprocal, linked relationship that shapes the fundamental character of landscapes and ecosystems. Disturbance creates and maintains biological diversity in the form of shifting, heterogeneous mosaics of diverse communities and habitats across a landscape (McKinney and Drake 1998), and biodiversity is generally highest when disturbance is neither too rare nor too frequent on the landscape (Grime 1973).

  18. Thayer Lake Hydropower Development -- Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Matousek, Mark

    The Thayer Lake Hydropower Development (THLD) has been under study since the late 1970’s as Angoon explored opportunities to provide lower cost renewable power to the Community and avoid the high cost of diesel generation. Kootznoowoo Inc. (Kootznoowoo), the tribal corporation for Angoon’s current and past residents, was provided the rights by Congress to develop a hydropower project within the Admiralty Island National Monument. This grant (DE-EE0002504) by the Department of Energy’s (DOE’s) Office of Indian Energy and a matching grant from the Alaska Energy Authority (AEA) were provided to Kootznoowoo to enable the design, engineering and permitting of thismore » hydropower project on Thayer Creek. Prior to the grant, the USFS had performed a final environmental impact statement (FEIS) and issued a Record of Decision (ROD) in 2009 for a 1.2 MW hydropower project on Thayer Creek that would Angoon’s needs with substantial excess capacity for growth. Kootznoowoo hired Alaska Power & Telephone (AP&T) in 2013 to manage this project and oversee its development. AP&T and its subcontractors under Kootznoowoo’s guidance performed several activities, aligned with the task plan defined in the grant.« less

  19. Mechanisms of the gabapentinoids and α 2 δ-1 calcium channel subunit in neuropathic pain.

    PubMed

    Patel, Ryan; Dickenson, Anthony H

    2016-04-01

    The gabapentinoid drugs gabapentin and pregabalin are key front-line therapies for various neuropathies of peripheral and central origin. Originally designed as analogs of GABA, the gabapentinoids bind to the α 2 δ-1 and α 2 δ-2 auxiliary subunits of calcium channels, though only the former has been implicated in the development of neuropathy in animal models. Transgenic approaches also identify α 2 δ-1 as key in mediating the analgesic effects of gabapentinoids, however the precise molecular mechanisms remain unclear. Here we review the current understanding of the pathophysiological role of the α 2 δ-1 subunit, the mechanisms of analgesic action of gabapentinoid drugs and implications for efficacy in the clinic. Despite widespread use, the number needed to treat for gabapentin and pregabalin averages from 3 to 8 across neuropathies. The failure to treat large numbers of patients adequately necessitates a novel approach to treatment selection. Stratifying patients by sensory profiles may imply common underlying mechanisms, and a greater understanding of these mechanisms could lead to more direct targeting of gabapentinoids.

  20. Inflammatory Role of Macrophage Xanthine Oxidoreductase in Pulmonary Hypertension: Implications for Novel Therapeutic Approaches

    DTIC Science & Technology

    2015-10-01

    Lung Inflammation, Uric Acid, Chronic Obstructive Pulmonary Disease, Mononuclear Phagocyte , Monosodium Urate, XOR WT, XOR KO, Wistar Kyoto, Pulmonary...0451 Annual Report (Year 1) 4 Mononuclear Phagocyte XOR Activity and Superoxide Generation Were Reduced by

  1. Self-perception of oral health in non-institutionalised elderly of Piracicaba city, Brazil.

    PubMed

    Esmeriz, Cláudia E C; Meneghim, Marcelo C; Ambrosano, Gláucia M B

    2012-06-01

    To associate the self-perception of oral health with sociodemographic, clinical, quality of life and geriatric depression, evaluating what influence in the self-perception of the elderly and the importance to the oral health.   The current demographic transition and poor oral health of the elderly deserves particular attention, especially the impact of oral health on the quality of life. In this cross-sectional study, we evaluated 371 elderly, aged 60 years or more, adscript to Health Family Units, Piracicaba city, Brazil. Clinically, the indexes decayed missing filled teeth (DMFT), CPI and Use/Need of Prosthesis (WHO/99) were used and evaluated by means of instruments such as the self-perceived oral health [geriatric oral health assessment index (GOHAI)], quality of life (SF-36) and geriatric depression (Geriatric Depression Scale). The statistical analyses were carried out by means of univariate analysis of chi-square and Fisher's exact (α = 0.05) and multiple logistic regression analysis. The mean age was 67.35 (2.8), with a mean DMFT of 28.5 (4.8) and a positive GOHAI score (>30). Most were women (63.3%), between 60 and 70 years (72.2%), married (60.4%), had just the elementary school (75.5%) education. Around 80% used some removable prosthetic. The results were associated with characteristics of self-perception of oral health and were significative of schooling (OR = 2.46) and the emotional aspects of quality of life (OR = 0.30). Over 20% of the sample had traits of depression, and these results were statistically significant (OR = 1.65) when associated with the GOHAI scores. Educational and emotional aspects and geriatric depression are factors that influence the positive self-perception of oral health of elderly people of Piracicaba USFs. These results represent that education, feelings and behaviours deserve special attention in their oral health, thereby approaching the self-perception of real dental condition. © 2011 The Gerodontology Society and John Wiley & Sons A/S.

  2. DOE Office of Scientific and Technical Information (OSTI.GOV)

    F. Robert Tabita

    The ocean/atmosphere interface is the major conduit for the entry of atmospheric CO2 into oceanic carbon pools that can lead to sequestration or recycled release. The surface layers of the temperate and tropical oceans are often too oligotrophic to result in significant primary production that might lead to carbon sequestration. However, nutrient-rich river plumes can alter the primary production schemes of oligotrophic ocean basins, resulting in increased phytoplankton biomass and carbon fixation. The ultimate goal of this proposal is to understand these carbon cycling processes in major river plumes from the molecular processes involved in biological DIC uptake to contributionmore » to basin-wide production and potential sequestration. Our research efforts include a field component to answer the questions raised concerning DIC in plumes entering ocean basins and an intensive genomics approach to understanding these processes on the cellular level using genomic fragments obtained from plume biota. This project is actually composed of 3 separate PI-initiated projects, including projects at the University of South Florida (USF) College of Marine Science, the University of Puerto Rico, and The Ohio State University. This report concerns research conducted at The Ohio State University and studies performed in collaboration with USF. In order to understand what might occur in the field, two model sysytems were studied in the laboratory. Carbon fixation in the unicellular cyanobacterium Synechococcus sp Strain PCC 7002 took place mainly through the CBB pathway. Nitrogen nutrition in cyanobacteria is regulated by NtcA, a transcriptional regulatory protein. We show that the rubisco activity and gene (rbcL) expression were not affected when cells were exposed to prolonged periods of nitrogen stress, however cells appear to use intracellular nitrogen reserves during nitrogen starvation. Transcripts of the global transcriptional regulator NtcA are expressed under nitrogen starved and nitrogen replete (nitrate or ammonia) growth conditions, with slight decrease in transcription in the presence of ammonia. These results suggest that intracellular levels of NtcA do not directly affect carbon metabolism. Gene expression of the other nitrogen regulatory signal transducer, encoded by glnB was also studied. The glnB gene was highly transcribed in nitrogen-limited cells compared to nitrogen depleted growth conditions. Therefore in the cyanobacterium Synechococcus sp PCC 7002, nitrogen does not affect the metabolic potential and carbon fixation. The NtcA regulator behaved differently and studies indicate that the product of the ntcA gene (NtcA) has an indirect effect on ca rbon assimilation and the genes involved in the carbon concentrating mechanism of strain 7002. The product of the ccmM gene plays an important role in carboxysome assembly and inorganic carbon transport within the cell. We hypothesized that under nitrogen limiting conditions the transcriptional regulator NtcA binds at the region upstream of ccmM, near the transcription start site, and blocks the transcription of ccmM. This hypothesis was experimentally proven. In another study, with USF researchers, we performed experiments in situ on RubisCO espression. To determine the relationship between expression of the major gene in carbon fixation, we evaluated rbcL mRNA abundance using novel quantitative PCR assays, phytoplankton cell analyses, photophysiological parameters, and pCO2 in and around the Mississippi River plume (MRP) in the Gulf of Mexico. Lower salinity (30–32) stations were dominated by rbcL mRNA concentrations from heterokonts; i.e., diatoms and pelagophytes, which were at least an order of magnitude greater than haptophytes, a-Synechococcus or high-light Prochlorococcus. However, rbcL transcript abundances were similar among these groups at oligotrophic stations (salinity 34–36). Diatom cell counts and heterokont rbcL RNA showed a strong negative correlation to seawater pCO2. While Prochlorococcus cells did not exhibit a large difference between low and high pCO2 water, Prochlorococcus rbcL RNA concentrations had a strong positive correlation to pCO2, suggesting a very low level of RuBisCO RNA transcription among Prochlorococcus in the plume waters, possibly due to their relatively poor carbon concentrating mechanisms (CCMs). These results provide molecular evidence that diatom/pelagophyte productivity is largely responsible for the large CO2 drawdown occurring in the MRP, based on the cooccurrence of elevated RuBisCO gene transcript concentrations from this group and reduced seawater pCO2 levels. This may partly be due to efficient CCMs that enable heterokont eukaryotes such as diatoms to continue fixing CO2 in the face of strong CO2 drawdown. This work represents the first attempt to relate in situ microbial gene expression to contemporaneous CO2 flux measurements in the ocean.« less

  3. Tourette Syndrome: A Review and Educational Implications.

    ERIC Educational Resources Information Center

    Bauer, Anne M.; Shea, Thomas M.

    1984-01-01

    Tourette Syndrome, a condition characterized by involuntary muscular and verbal tics, is defined, its course described, incidence noted (possibly 1.6 percent of the population), etiology considered (from viewpoints of psychogenic and organic theories), treatment (primarily pharmaceutical therapy) discussed, and educational approaches examined.…

  4. Ecosystem Consequences of Prolonged Ozone Pollution in the Southern Sierra Nevada

    NASA Astrophysics Data System (ADS)

    Cousins, S.; Battles, J. J.; Cisneros, R.; Esperanza, A.; Swenson, D.

    2015-12-01

    While acute O3 exposure is widely known to damage plant tissues, the chronic effects on long lived organisms such as trees remain unclear. In the southern Sierra Nevada, O3 pollution has afflicted pine-dominated forests for over 40 years. Here we report the results of a long-term study of O3 impact on tree injury, growth, and mortality. Our study employed a network of forest plots along a gradient of O3 pollution with recurring measurements from 1991-2012. Over the same period and locations, summer O3 was monitored via partnership with USNPS and USFS, making this one of the longest known ecosystem studies of O3 pollution and its effects. We found that exposure at the most polluted sites declined 33%, from a W126 index of 20.12 ppm-hrs in 1992 to 13.5 ppm-hrs in 2012. The severity of foliar pollution damage at these sites also declined, from 43.9 on the 0-100 Ozone Injury Index (OII) scale to 34.2, a drop of 22%. At locations with lower O3 exposure, damage declined from OII of 16.9 to 9.2. Mean annual tree mortality rates over the 20 year period, calculated with a profile likelihood approach, were 0.5%/yr (95% CI 0.3 to 0.8 %/yr). This rate is similar to that of healthy canopy trees in similar unpolluted stands. However, low and declining tree growth rates reveal possible ecosystem impacts of prolonged exposure to pollution. Across affected sites, mean relative growth rates were 1.1%/yr in 1991-2000, and just 0.9%/yr in 2000-2011, a decline of 15.6% in the second decade. Initial analyses suggest that tree damage is positively correlated with June-October O3, as indicated by previous studies. Further analysis will explore the drivers of ecosystem impacts and roles of other natural and anthropogenic stressors, including variation in climatic water deficit. Understanding the consequences of prolonged O3 exposure on both individual trees and complex forest ecosystems helps identify the hidden environmental costs of tropospheric O3 and potential benefits of cleaner air.

  5. Dissecting Daily and Circadian Expression Rhythms of Clock-Controlled Genes in Human Blood.

    PubMed

    Lech, Karolina; Ackermann, Katrin; Revell, Victoria L; Lao, Oscar; Skene, Debra J; Kayser, Manfred

    2016-02-01

    The identification and investigation of novel clock-controlled genes (CCGs) has been conducted thus far mainly in model organisms such as nocturnal rodents, with limited information in humans. Here, we aimed to characterize daily and circadian expression rhythms of CCGs in human peripheral blood during a sleep/sleep deprivation (S/SD) study and a constant routine (CR) study. Blood expression levels of 9 candidate CCGs (SREBF1, TRIB1, USF1, THRA1, SIRT1, STAT3, CAPRIN1, MKNK2, and ROCK2), were measured across 48 h in 12 participants in the S/SD study and across 33 h in 12 participants in the CR study. Statistically significant rhythms in expression were observed for STAT3, SREBF1, TRIB1, and THRA1 in samples from both the S/SD and the CR studies, indicating that their rhythmicity is driven by the endogenous clock. The MKNK2 gene was significantly rhythmic in the S/SD but not the CR study, which implies its exogenously driven rhythmic expression. In addition, we confirmed the circadian expression of PER1, PER3, and REV-ERBα in the CR study samples, while BMAL1 and HSPA1B were not significantly rhythmic in the CR samples; all 5 genes previously showed significant expression in the S/SD study samples. Overall, our results demonstrate that rhythmic expression patterns of clock and selected clock-controlled genes in human blood cells are in part determined by exogenous factors (sleep and fasting state) and in part by the endogenous circadian timing system. Knowledge of the exogenous and endogenous regulation of gene expression rhythms is needed prior to the selection of potential candidate marker genes for future applications in medical and forensic settings. © 2015 The Author(s).

  6. World-View Entrapment: Moral-Ethical Implications for Gifted Education.

    ERIC Educational Resources Information Center

    Ambrose, Don

    2000-01-01

    This article explores the moral-ethical implications of the mechanistic world view and related issues such as technological determinism, social Darwinism, and androcentrism. It finds that educational approaches reinforced by the mechanistic world view include positivistic approaches to curriculum, instruction, and research. Recommendations for…

  7. National-scale aboveground biomass geostatistical mapping with FIA inventory and GLAS data: Preparation for sparsely sampled lidar assisted forest inventory

    NASA Astrophysics Data System (ADS)

    Babcock, C. R.; Finley, A. O.; Andersen, H. E.; Moskal, L. M.; Morton, D. C.; Cook, B.; Nelson, R.

    2017-12-01

    Upcoming satellite lidar missions, such as GEDI and IceSat-2, are designed to collect laser altimetry data from space for narrow bands along orbital tracts. As a result lidar metric sets derived from these sources will not be of complete spatial coverage. This lack of complete coverage, or sparsity, means traditional regression approaches that consider lidar metrics as explanatory variables (without error) cannot be used to generate wall-to-wall maps of forest inventory variables. We implement a coregionalization framework to jointly model sparsely sampled lidar information and point-referenced forest variable measurements to create wall-to-wall maps with full probabilistic uncertainty quantification of all inputs. We inform the model with USFS Forest Inventory and Analysis (FIA) in-situ forest measurements and GLAS lidar data to spatially predict aboveground forest biomass (AGB) across the contiguous US. We cast our model within a Bayesian hierarchical framework to better model complex space-varying correlation structures among the lidar metrics and FIA data, which yields improved prediction and uncertainty assessment. To circumvent computational difficulties that arise when fitting complex geostatistical models to massive datasets, we use a Nearest Neighbor Gaussian process (NNGP) prior. Results indicate that a coregionalization modeling approach to leveraging sampled lidar data to improve AGB estimation is effective. Further, fitting the coregionalization model within a Bayesian mode of inference allows for AGB quantification across scales ranging from individual pixel estimates of AGB density to total AGB for the continental US with uncertainty. The coregionalization framework examined here is directly applicable to future spaceborne lidar acquisitions from GEDI and IceSat-2. Pairing these lidar sources with the extensive FIA forest monitoring plot network using a joint prediction framework, such as the coregionalization model explored here, offers the potential to improve forest AGB accounting certainty and provide maps for post-model fitting analysis of the spatial distribution of AGB.

  8. My genes made me do it? The implications of behavioural genetics for responsibility and blame.

    PubMed

    Levitt, Mairi; Manson, Neil

    2007-03-01

    The idea of individual responsibility for action is central to our conception of what it is to be a person. Behavioural genetic research may seem to call into question the idea of individual responsibility with possible implications for the criminal justice system. These implications will depend on the understandings of the various agencies and professional groups involved in responding to violent and anti-social behaviour, and, the result of negotiations between them over resulting practice. The paper considers two kinds of approaches to the question of responsibility and 'criminal genes' arising from a sociological and philosophical perspective respectively. One is to consider the social context and possible practical implications of research into 'criminal genes' which will later be examined through interviews and discussions with a range of experts including lawyers and social workers. A second and different kind of approach is to ask whether the findings of behavioural genetics ought to have implications for attributions of responsibility. Issues of genetic influence are central to both approaches.

  9. Decision Analysis: Engineering Science or Clinical Art

    DTIC Science & Technology

    1979-11-01

    TECHNICAL REPORT TR 79-2-97 DECISION ANALYSIS: ENGINEERING SCIENCE OR CLINICAL ART ? by Dennis M. Buede Prepared for Defense Advanced Research...APPLICATIONS OF THE ENGINEER- ING SCIENCE AND CLINICAL ART EXTREMES 9 3.1 Applications of the Engineering Science Approach 9 3.1.1 Mexican electrical...DISCUSSION 29 4.1 Engineering Science versus Clinical Art : A Characterization of When Each is Most Attractive 30 4.2 The Implications of the Engineering

  10. Intercultural Counselling and Assessment: Global Perspectives.

    ERIC Educational Resources Information Center

    Samuda, Ronald J., Ed.; Wolfgang, Aaron, Ed.

    This book concerning the need for more appropriate approaches to intercultural counseling in counselor training includes these articles: (1) "Comparative Immigration Patterns in the U.S., Australia and Canada: Social and Educational Implications" (R. J. Samuda); (2) "Theories of Counselling: A Comparative Analysis" (C. E.…

  11. Conceptualizing and Assessing Self-Enhancement Bias: A Componential Approach

    PubMed Central

    Kwan, Virginia S. Y.; Kuang, Lu Lu; John, Oliver P.; Robins, Richard W.

    2014-01-01

    Four studies implemented a componential approach to assessing self-enhancement and contrasted this approach with 2 earlier ones: social comparison (comparing self-ratings with ratings of others) and self-insight (comparing self-ratings with ratings by others). In Study 1, the authors varied the traits being rated to identify conditions that lead to more or less similarity between approaches. In Study 2, the authors examined the effects of acquaintance on the conditions identified in Study 1. In Study 3, the authors showed that using rankings renders the self-insight approach equivalent to the component-based approach but also has limitations in assessing self-enhancement. In Study 4, the authors compared the social-comparison and the component-based approaches in terms of their psychological implications; the relation between self-enhancement and adjustment depended on the self-enhancement approach used, and the positive-adjustment correlates of the social-comparison approach disappeared when the confounding influence of the target effect was controlled. PMID:18505318

  12. Potential Implications of Approaches to Climate Change on the Clean Water Rule Definition of "Waters of the United States".

    PubMed

    Faust, Derek R; Moore, Matthew T; Emison, Gerald Andrews; Rush, Scott A

    2016-05-01

    The 1972 Clean Water Act was passed to protect chemical, physical, and biological integrity of United States' waters. The U.S. Environmental Protection Agency and U.S. Army Corps of Engineers codified a new "waters of the United States" rule on June 29, 2015, because several Supreme Court case decisions caused confusion with the existing rule. Climate change could affect this rule through connectivity between groundwater and surface waters; floodplain waters and the 100-year floodplain; changes in jurisdictional status; and sea level rise on coastal ecosystems. Four approaches are discussed for handling these implications: (1) "Wait and see"; (2) changes to the rule; (3) use guidance documents; (4) Congress statutorily defining "waters of the United States." The approach chosen should be legally defensible and achieved in a timely fashion to provide protection to "waters of the United States" in proactive consideration of scientifically documented effects of climate change on aquatic ecosystems.

  13. Positively Influencing Gifted Education Policy

    ERIC Educational Resources Information Center

    Plucker, Jonathan A.

    2012-01-01

    The approach proposed by Subotnik, Olszewski-Kubilius, and Worrell (2011) has significant implications for the field of gifted education, many of which would increase advocates' ability to achieve success when working with policy makers. This commentary explores those implications and examines how the proposed approach can be integrated within the…

  14. Energizing the future: New battery technology a reality today

    NASA Astrophysics Data System (ADS)

    Chase, Henry; Bitterly, Jack; Federici, Al

    1997-04-01

    The U.S. Flywheel Systems' flywheel energy storage system could be the answer to a critical question: How do we replace conventional chemical batteries with a more-efficient system that lasts longer and is non-polluting? The new product, which has a virtually unlimited life expectancy, has a storage capacity four times greater per pound than conventional chemical batteries. USFS designed and built each component of the system—from the specially wound carbon fiber wheel, the magnetic bearing, the motor/generator, and the electronic control. The flywheel is designed to spin at speeds up to 100,000 rpm and deliver about 50 horsepower using a proprietary high-speed, high-power-density motor/generator that is the size of a typical coffee mug. Some of the important markets and applications for the flywheel storage system include electric vehicles, back-up power supply, peak power smoothing, satellite energy storage systems, and locomotive power.

  15. Burn severity mapping in Australia 2009

    USGS Publications Warehouse

    McKinley, Randy; Clark, J.; Lecker, Jennifer

    2012-01-01

    In 2009, the Victoria Department of Sustainability and Environment estimated approximately 430,000 hectares of Victoria Australia were burned by numerous bushfires. Burned Area Emergency Response (BAER) teams from the United States were deployed to Victoria to assist local fire managers. The U.S. Geological Survey Earth Resources Observation and Science Center (USGS/EROS) and U.S. Forest Service Remote Sensing Applications Center (USFS/RSAC) aided the support effort by providing satellite-derived "soil burn severity " maps for over 280,000 burned hectares. In the United States, BAER teams are assembled to make rapid assessments of burned lands to identify potential hazards to public health and property. An early step in the assessment process is the creation of a soil burn severity map used to identify hazard areas and prioritize treatment locations. These maps are developed primarily using Landsat satellite imagery and the differenced Normalized Burn Ratio (dNBR) algorithm.

  16. NASA's Applied Sciences: Natural Disasters Program

    NASA Technical Reports Server (NTRS)

    Kessler, Jason L.

    2010-01-01

    Fully utilize current and near-term airborne and spaceborne assets and capabilities. NASA spaceborne instruments are for research but can be applied to natural disaster response as appropriate. NASA airborne instruments can be targeted specifically for disaster response. Could impact research programs. Better flow of information improves disaster response. Catalog capability, product, applicable disaster, points of contact. Ownership needs to come from the highest level of NASA - unpredictable and irregular nature of disasters requires contingency funding for disaster response. Build-in transfer of applicable natural disaster research capabilities to operational functionality at other agencies (e.g., USFS, NOAA, FEMA...) at the outset, whenever possible. For the Decadal Survey Missions, opportunities exist to identify needs and requirements early in the mission design process. Need to understand additional needs and commitments for meeting the needs of the disaster community. Opportunity to maximize disaster response and mitigation from the Decadal Survey Missions. Additional needs or capabilities may require agency contributions.

  17. Using Landsat to Diagnose Trends in Disturbance Magnitude Across the National Forest System

    NASA Astrophysics Data System (ADS)

    Hernandez, A. J.; Healey, S. P.; Stehman, S. V.; Ramsey, R. D.

    2014-12-01

    The Landsat archive is increasingly being used to detect trends in the occurrence of forest disturbance. Beyond information about the amount of area affected, forest managers need to know if and how disturbance severity is changing. For example, the United States National Forest System (NFS) has developed a comprehensive plan for carbon monitoring, which requires a detailed temporal mapping of forest disturbance magnitudes across 75 million hectares. To meet this need, we have prepared multitemporal models of percent canopy cover that were calibrated with extensive field data from the USFS Forest Inventory and Analysis Program (FIA). By applying these models to pre- and post-event Landsat images at the site of known disturbances, we develop maps showing first-order estimates of disturbance magnitude on the basis of cover removal. However, validation activities consistently show that these initial estimates under-estimate disturbance magnitude. We have developed an approach, which quantifies this under-prediction at the landscape level and uses empirical validation data to adjust change magnitude estimates derived from initial disturbance maps. In an assessment of adjusted magnitude trends of NFS' Northern Region from 1990 to the present, we observed significant declines since 1990 (p < .01) in harvest magnitude, likely related to known reduction of clearcutting practices in the region. Fire, conversely, did not show strongly significant trends in magnitude, despite an increase in the overall area affected. As Landsat is used to provide increasingly precise maps of the timing and location of historical forest disturbance, a logical next step is to use the archive to generate widely interpretable and objective estimates of disturbance magnitude.

  18. Implications of Climate Change for State Bioassessment Programs and Approaches to Account for Effects (Final Report)

    EPA Science Inventory

    EPA announced the availability of the final report, Implications of Climate Change for State Bioassessment Programs and Approaches to Account for Effects. This report uses biological data collected by four states in wadeable rivers and streams to examine the components ...

  19. Qualitative Audience Research: Toward an Integrative Approach to Reception.

    ERIC Educational Resources Information Center

    Jensen, Klaus Bruhn

    1987-01-01

    Analyzes research about the mass communication audience and describes a theoretical and methodological framework for further empirical studies. Discusses the (1) explanatory value of qualitative research; (2) social and cultural implications of the reception process, with special reference to television; and (3) applications and social relevance…

  20. Mars Global Surveyor Data Analysis Program. Origins of Small Volcanic Cones: Eruption Mechanisms and Implications for Water on Mars

    NASA Technical Reports Server (NTRS)

    Fagents, Sarah A.; Greeley, Ronald; Thordarson, Thorvaldur

    2002-01-01

    The goal of the proposed work was to determine the origins of small volcanic cones observed in Mars Global Surveyor (MGS) data, and their implications for regolith ice stores and magma volatile contents. For this 1-year study, our approach involved a combination of: Quantitative morphologic analysis and interpretation of Mars Orbiter Camera (MOC) and Mars Orbiter Laser Altimeter (MOLA) data; Numerical modeling of eruption processes responsible for producing the observed features; Fieldwork on terrestrial analogs in Iceland. Following this approach, this study succeeded in furthering our understanding of (i) the spatial and temporal distribution of near-surface water ice, as defined by the distribution and sizes of rootless volcanic cones ("pseudocraters"), and (ii) the properties, eruption conditions, and volatile contents of magmas producing primary vent cones.

  1. The Management of the Enrichment Curriculum in Public "Madrasah Aliyah 1 Unggulan" Tulungagung Indonesia

    ERIC Educational Resources Information Center

    Manab, Abdul

    2015-01-01

    The objective of this research is to examine: 1) the background in doing the curriculum enrichment; 2) the stages in managing the curriculum enrichment, and 3) the implications and the management of the curriculum enrichment. It is qualitative and naturalistic in nature with a case-study approach and, an interpretative analysis was made on the…

  2. A mechanism to derive more truthful willingness to accept values for renewable energy systems.

    PubMed

    Radmehr, Mehrshad; Willis, Ken; Metcalf, Hugh

    2018-01-01

    This paper examines and compares households' willingness to accept (WTA)/willingness to pay (WTP) ratio for solar power equipment on their premises through both a novel experimental approach and conventional techniques. The experimental approach was administered by using a Becker-DeGroot-Marschak method and cheap talk, with open-ended questions of WTA/WTP. The results were quite striking. The ratio for the incentivised approach was 1.08:1; whereas for the conventional approach it was 3.5:1. The findings suggest that the hypothesis that WTP equals WTA cannot be rejected for the incentivised mechanism, and it appears to control for the individual's strategic behaviour bias as a treatment against over-estimating WTA and under-estimating WTP. The findings also provide some policy implications for Northern Cyprus: the government can set lower financial incentives to increase the solar power installed capacity on the island.

  3. Constraints on the Observation of Partial Match Costs: Implications for Transfer-Appropriate Processing Approaches to Immediate Priming

    ERIC Educational Resources Information Center

    Leboe, Jason P.; Leboe, Launa C.; Milliken, Bruce

    2010-01-01

    According to a transfer-appropriate processing framework, immediate priming costs arise from a match between a prime and probe event on 1 dimension and a difference between those 2 events on some other dimension (i.e., a partial match). In Experiment 1, the authors used a Stroop priming procedure to generate 6 variants of partial match, yet only 1…

  4. Nanoparticle Based Galectin-1 Gene Silencing, Implications in Methamphetamine Regulation of HIV-1 Infection in Monocyte Derived Macrophages

    PubMed Central

    Law, Wing Cheung; Mahajan, Supriya D.; Aalinkeel, Ravikumar; Nair, Bindukumar; Sykes, Donald E.; Yong, Ken-Tye; Hui, Rui; Prasad, Paras N.; Schwartz, Stanley A.

    2012-01-01

    Galectin-1, an adhesion molecule, is expressed in macrophages and implicated in human immunodeficiency virus (HIV-1) viral adsorption. In this study, we investigated the effects of methamphetamine on galectin-1 production in human monocyte derived macrophages (MDM) and the role of galectin-1 in methamphetamine potentiation of HIV-1 infection. Herein we show that levels of galectin-1 gene and protein expression are significantly increased by meth-amphetamine. Furthermore, concomitant incubation of MDM with galectin-1 and methamphetamine facilitates HIV-1 infection compared to galectin-1 alone or methamphetamine alone. We utilized a nanotechnology approach that uses gold nanorod (GNR)-galectin-1 siRNA complexes (nanoplexes) to inhibit gene expression for galectin-1. Nanoplexes significantly silenced gene expression for galectin-1 and reversed the effects of methamphetamine on galectin-1 gene expression. Moreover, the effects of methamphetamine on HIV-1 infection were attenuated in the presence of the nanoplex in MDM. PMID:22689223

  5. Human-Centered Systems Analysis of Aircraft Separation from Adverse Weather: Implications for Icing Remote Sensing

    NASA Technical Reports Server (NTRS)

    Vigeant-Langlois, Laurence; Hansman, R. John, Jr.

    2003-01-01

    The objective of this project was to propose a means to improve aviation weather information, training procedures based on a human-centered systems approach. Methodology: cognitive analysis of pilot's tasks; trajectory-based approach to weather information; contingency planning support; and implications for improving weather information.

  6. Learning Styles. What Research Says to the Teacher Series.

    ERIC Educational Resources Information Center

    Reiff, Judith C.

    This monograph reviews several approaches for describing learning styles and the instructional implications of an emphasis on learning styles for teachers. Several reasons for the importance of understanding individual learning styles are provided; such understanding leads to: (1) reduction of teacher and student frustration; (2) higher student…

  7. On Dual Processing and Heuristic Approaches to Moral Cognition

    ERIC Educational Resources Information Center

    Lapsley, Daniel K.; Hill, Patrick L.

    2008-01-01

    We examine the implications of dual-processing theories of cognition for the moral domain, with particular emphasis upon "System 1" theories: the Social Intuitionist Model (Haidt), moral heuristics (Sunstein), fast-and-frugal moral heuristics (Gigerenzer), schema accessibility (Lapsley & Narvaez) and moral expertise (Narvaez). We argue that these…

  8. Toilet Training, Cueing, Praise, and Self-Cleaning in the Treatment of Classroom Encopresis: A Case Study.

    ERIC Educational Resources Information Center

    Dixon, Joe W.; Saudargas, Richard A.

    1980-01-01

    Reports a successful method of teaching toileting procedures to a young elementary student. Implications discussed for school psychologists were: (1) handling intervention through a consultation model; (2) using the simplest approach before attempting more powerful procedures; and (3) attempting treatment despite previously unsuccessful…

  9. Six Acts of Miscognition: Implications for Art Education

    ERIC Educational Resources Information Center

    Tavin, Kevin M.

    2010-01-01

    Employing Lacanian theory as a necessary supplement to contemporary approaches in art education, this article provides a critique and response to art education discourse around "cognition." This response unfolds in six acts: (1) Unknown knowledge, (2) Unmeant knowledge, (3) Missing metaphors, (4) Stupidity, (5) Symptoms and sinthomes, and (6)…

  10. From Quality Assurance to Quality Enhancement in the European Higher Education Area

    ERIC Educational Resources Information Center

    Gvaramadze, Irakli

    2008-01-01

    This article focuses on recent trends in quality assurance initiatives, analyses how the European Higher Education Area promotes quality enhancement mechanisms and their implications for quality cultures in universities. It presents and discusses two approaches towards quality enhancement both at the institutional and programme level: 1. Quality…

  11. A Person-Oriented Approach: Methods for Today and Methods for Tomorrow

    ERIC Educational Resources Information Center

    Bergman, Lars R.; El-Khouri, Bassam M.

    2003-01-01

    Methodological implications of a person-oriented, holistic-interactionistic perspective in research on individual development are outlined, desirable properties of a mathematical model of a phenomenon are discussed, and selected methods for carrying out person-oriented research are briefly overviewed. These methods are: (1) the classificatory…

  12. Monitoring Fires from Space: a case study in transitioning from research to applications

    NASA Astrophysics Data System (ADS)

    Justice, C. O.; Giglio, L.; Vadrevu, K. P.; Csiszar, I. A.; Schroeder, W.; Davies, D.

    2012-12-01

    This paper discusses the heritage and relationships between science and applications in the context of global satellite-based fire monitoring. The development of algorithms for satellite-based fire detection has been supported primarily by NASA for the polar orbiters with a global focus, and initially by NOAA and more recently by EUMETSAT for the geostationary satellites, with a regional focus. As the feasibility and importance of space-based fire monitoring was recognized, satellite missions were designed to include fire detection capabilities. As a result, the algorithms and accuracy of the detections have improved. Due to the role of fire in the Earth System and its relevance to society, at each step in the development of the sensing capability the research has made a transition into fire-related applications to such an extent that there is now broad use of these data worldwide. The origin of the polar-orbiting satellite fire detection capability was with the AVHRR sensor beginning in the early 1980s, but was transformed with the launch of the EOS MODIS instruments, which included sensor characteristics specifically for fire detection. NASA gave considerable emphasis on the accuracy assessment of the fire detection and the development of fire characterization and burned area products from MODIS. Collaboration between the MODIS Fire Team and the RSAC USFS, initiated in the context of the Montana wildfires of 2001, prompted the development of a Rapid Response System for fire data and eventually led to operational use of MODIS data by the USFS for strategic fire monitoring. Building on this success, the Fire Information for Resource Management Systems (FIRMS) project was funded by NASA Applications to further develop products and services for the fire information community. The FIRMS was developed as a web-based geospatial tool, offering a range of geospatial data services, including SMS text messaging and is now widely used. This system, developed in the research domain, has now been successfully moved to an operational home at the UN FAO, as the Global Fire Information Management System (GFIMS). With a view to operational data continuity, the Suomi-NPP/JPSS VIIRS system was also designed with a fire detection capability, and is providing promising results for fire monitoring both from the standard operational production system and experimental product enhancements. International coordination on fire observations and outreach has been successfully developed under the GOFC GOLD program.

  13. The Role of Dietary Protein and Fat in Glycaemic Control in Type 1 Diabetes: Implications for Intensive Diabetes Management.

    PubMed

    Paterson, Megan; Bell, Kirstine J; O'Connell, Susan M; Smart, Carmel E; Shafat, Amir; King, Bruce

    2015-09-01

    A primary focus of the management of type 1 diabetes has been on matching prandial insulin therapy with carbohydrate amount consumed. However, even with the introduction of more flexible intensive insulin regimes, people with type 1 diabetes still struggle to achieve optimal glycaemic control. More recently, dietary fat and protein have been recognised as having a significant impact on postprandial blood glucose levels. Fat and protein independently increase the postprandial glucose excursions and together their effect is additive. This article reviews how the fat and protein in a meal impact the postprandial glycaemic response and discusses practical approaches to managing this in clinical practice. These insights have significant implications for patient education, mealtime insulin dose calculations and dosing strategies.

  14. Motivation modulates the effect of approach on implicit preferences.

    PubMed

    Zogmaister, Cristina; Perugini, Marco; Richetin, Juliette

    2016-08-01

    With three studies, we investigated whether motivational states can modulate the formation of implicit preferences. In Study 1, participants played a video game in which they repeatedly approached one of two similar beverages, while disregarding the other. A subsequent implicit preference for the target beverage emerged, which increased with participants' thirst. In Study 2, participants approached one brand of potato chips while avoiding the other: Conceptually replicating the moderation observed in Study 1, the implicit preference for the approached brand increased with the number of hours from last food intake. In Study 3, we experimentally manipulated hunger, and the moderation effect emerged again, with hungry participants displaying a higher implicit preference for the approached brand, as compared to satiated participants. In the three studies, the moderation effect was not paralleled in explicit preferences although the latter were affected by the preference inducing manipulation. Theoretical implications and open questions are discussed.

  15. Transfemoral transcatheter aortic valve insertion-related intraoperative morbidity: Implications of the minimalist approach.

    PubMed

    Greason, Kevin L; Pochettino, Alberto; Sandhu, Gurpreet S; King, Katherine S; Holmes, David R

    2016-04-01

    Transfemoral transcatheter aortic valve insertion may be performed in a catheterization laboratory (ie, the minimalist approach). It seems reasonable when considering this approach to avoid it in patients at risk for intraoperative morbidity that would require surgical intervention. We hypothesized that it would be possible to associate baseline characteristics with such morbidity, which would help heart teams select patients for the minimalist approach. We reviewed the records of 215 consecutive patients who underwent transfemoral transcatheter aortic valve insertion with a current commercially available device from November 2008 through July 2015. Demographic characteristics of the patients included a mean age of 78.9 ± 10.6 years, female sex in 73 patients (34.0%), and a mean Society of Thoracic Surgeons predicted risk of mortality of 8.7% ± 5.4%. Valve prostheses were balloon-expandable in 126 patients (58.6%) and self-expanding in 89 patients (41.4%). Significant intraoperative morbidity occurred in 22 patients (10.2%) and included major vascular injury in 12 patients (5.6%), hemodynamic compromise requiring cardiopulmonary bypass support in 4 patients (1.9%), cardiac tamponade requiring intervention in 3 patients (1.4%), ventricular valve embolization in 2 patients (0.9%), and inability to obtain percutaneous access requiring open vascular access in 1 patient (0.5%). Intraoperative morbidity was similarly distributed across all valve types (P = .556) and sheath sizes (P = .369). There were no baseline patient characteristics predictive of intraoperative morbidity. Patient and valve characteristics are not predictive of significant intraoperative morbidity during transfemoral transcatheter aortic valve insertion. The finding has implications for patient selection for the minimalist approach. Copyright © 2016 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.

  16. Lead discovery and chemical biology approaches targeting the ubiquitin proteasome system.

    PubMed

    Akinjiyan, Favour A; Carbonneau, Seth; Ross, Nathan T

    2017-10-15

    Protein degradation is critical for proteostasis, and the addition of polyubiquitin chains to a substrate is necessary for its recognition by the 26S proteasome. Therapeutic intervention in the ubiquitin proteasome system has implications ranging from cancer to neurodegeneration. Novel screening methods and chemical biology tools for targeting E1-activating, E2-conjugating and deubiquitinating enzymes will be discussed in this review. Approaches for targeting E3 ligase-substrate interactions as well as the proteasome will also be covered, with a focus on recently described approaches. Copyright © 2017. Published by Elsevier Ltd.

  17. Spatial distribution of diesel transit bus emissions and urban populations: implications of coincidence and scale on exposure.

    PubMed

    Gouge, Brian; Ries, Francis J; Dowlatabadi, Hadi

    2010-09-15

    Macroscale emissions modeling approaches have been widely applied in impact assessments of mobile source emissions. However, these approaches poorly characterize the spatial distribution of emissions and have been shown to underestimate emissions of some pollutants. To quantify the implications of these limitations on exposure assessments, CO, NO(X), and HC emissions from diesel transit buses were estimated at 50 m intervals along a bus rapid transit route using a microscale emissions modeling approach. The impacted population around the route was estimated using census, pedestrian count and transit ridership data. Emissions exhibited significant spatial variability. In intervals near major intersections and bus stops, emissions were 1.6-3.0 times higher than average. The coincidence of these emission hot spots and peaks in pedestrian populations resulted in a 20-40% increase in exposure compared to estimates that assumed homogeneous spatial distributions of emissions and/or populations along the route. An additional 19-30% increase in exposure resulted from the underestimate of CO and NO(X) emissions by macroscale modeling approaches. The results of this study indicate that macroscale modeling approaches underestimate exposure due to poor characterization of the influence of vehicle activity on the spatial distribution of emissions and total emissions.

  18. [MATCHE: Management Approach to Teaching Consumer and Homemaking Education.] Consumer Approach Strand: Textiles and Clothing. Module I-D-4: Applications and Implications of New Technology in Textiles and Clothing.

    ERIC Educational Resources Information Center

    Joseph, Marjory

    This competency-based preservice home economics teacher education module on applications and implications of new technology in textiles and clothing is the fourth in a set of four modules on consumer education related to textiles and clothing. (This set is part of a larger series of sixty-seven modules on the Management Approach to Teaching…

  19. Evaluation of improved land use and canopy representation in ...

    EPA Pesticide Factsheets

    Biogenic volatile organic compounds (BVOC) participate in reactions that can lead to secondarily formed ozone and particulate matter (PM) impacting air quality and climate. BVOC emissions are important inputs to chemical transport models applied on local to global scales but considerable uncertainty remains in the representation of canopy parameterizations and emission algorithms from different vegetation species. The Biogenic Emission Inventory System (BEIS) has been used to support both scientific and regulatory model assessments for ozone and PM. Here we describe a new version of BEIS which includes updated input vegetation data and canopy model formulation for estimating leaf temperature and vegetation data on estimated BVOC. The Biogenic Emission Landuse Database (BELD) was revised to incorporate land use data from the Moderate Resolution Imaging Spectroradiometer (MODIS) land product and 2006 National Land Cover Database (NLCD) land coverage. Vegetation species data are based on the US Forest Service (USFS) Forest Inventory and Analysis (FIA) version 5.1 for 2002–2013 and US Department of Agriculture (USDA) 2007 census of agriculture data. This update results in generally higher BVOC emissions throughout California compared with the previous version of BEIS. Baseline and updated BVOC emission estimates are used in Community Multiscale Air Quality (CMAQ) Model simulations with 4 km grid resolution and evaluated with measurements of isoprene and monoterp

  20. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hutchinson, Kenneth

    To perform remedial vegetation management for keeping vegetation a safe distance away from electric power facilities and controlling noxious weeds within a section of BPA's Big Eddy-Ostrander Transmission Corridor. During a site review conducted in late fall of 2001, the inspector observed various species of hardwood trees resprouted from stumps. The new vegetative growth encroached on the required “Minimum Safe Distance” between the top of vegetation and the conductor cables. The management action is necessary to reduce the current and potential future hazards that tall-growing vegetation poses to transmission conductors. In addition, BPA will include weed control as part ofmore » their remedial vegetation management action. Noxious weeds occur within the corridor. Under a 1999 Executive Order, all federal agencies are required to detect and control noxious weeds. In addition, BPA is required under the 1990 amendment to the Noxious Weed Act (7 USC 2801-2814) to manage undesirable plants on federal land. Also, the Bonneville Power Administration (BPA) has responsibility to manage noxious weeds under the Transmission System Vegetation Management Program Final Environmental Impact Statement (FEIS).1 State statutes and regulations also mandate action by BPA and the USFS to control noxious weeds. The Oregon Department of Agriculture (ODA) has requested that agencies aggressively control these weeds before additional spread occurs.« less

  1. Near-Real-Time Earth Observation Data Supporting Wildfire Management

    NASA Astrophysics Data System (ADS)

    Ambrosia, V. G.; Zajkowski, T.; Quayle, B.

    2013-12-01

    During disaster events, the most critical element needed by responding personnel and management teams is situational intelligence / awareness. During rapidly-evolving events such as wildfires, the need for timely information is critical to save lives, property and resources. The wildfire management agencies in the US rely heavily on remote sensing information both from airborne platforms as well as from orbital assets. The ability to readily have information from those systems, not just data, is critical to effective control and damage mitigation. NASA has been collaborating with the USFS to mature and operationalize various asset-information capabilities to effect improved knowledge of fire-prone areas, monitor wildfire events in real-time, assess effectiveness of fire management strategies, and provide rapid, post-fire assessment for recovery operations. Specific examples of near-real-time remote sensing asset utility include daily MODIS data employed to assess fire potential / wildfire hazard areas, and national-scale hot-spot detection, airborne thermal sensor collected during wildfire events to effect management strategies, EO-1 ALI 'pointable' satellite sensor data to assess fire-retardant application effectiveness, and Landsat 8 and other sensor data to derive burn severity indices for post-fire remediation work. These cases of where near-real-time data is used operationally during the previous few fire seasons will be presented.

  2. A highly sensitive magnetic biosensor for detection and quantification of anticancer drugs tagged to superparamagnetic nanoparticles

    NASA Astrophysics Data System (ADS)

    Wingo, J.; Devkota, J.; Mai, T. T. T.; Nguyen, X. P.; Mukherjee, P.; Srikanth, H.; Phan, M. H.; Vietnam Academy of Science and Technology Collaboration; University of South Florida Team

    2014-03-01

    A precise detection of low concentrations of biomolecules attached to magnetic nanoparticles in complex biological systems is a challenging task and requires biosensors with improved sensitivity. Here, we present a highly sensitive magnetic biosensor based on the magneto-reactance (MX) effect of a Co65Fe4Ni2Si15B14 amorphous ribbon with nanohole-patterned surface for detection and quantification of anticancer drugs (Curcumin) tagged to Fe3O4 nanoparticles. The detection and quantification of Curcumin were assessed by the change in MX of the ribbon subject to varying concentrations of the functionalized Fe3O4 nanoparticles. A high capacity of the MX-based biosensor in quantitative analysis of the nanoparticles was achieved in the range of 0 - 50 ng/ml, beyond which the detection sensitivity (η) remained unchanged. The η of the biosensor reached an extremely high value of 30%, which is about 4-5 times higher than that of a magneto-impedance (MI) based biosensor. This biosensor is well suited for detection of low-concentration magnetic biomarkers in biological systems. This work was supported by was supported by the Florida Cluster for Advanced Smart Sensor Technologies, USAMRMC (Grant # W81XWH-07-1-0708), and the NSF-funded REU program at the USF.

  3. Space Station Human Factors Research Review. Volume 1: EVA Research and Development

    NASA Technical Reports Server (NTRS)

    Cohen, Marc M. (Editor); Vykukal, H. C. (Editor)

    1988-01-01

    An overview is presented of extravehicular activity (EVA) research and development activities at Ames. The majority of the program was devoted to presentations by the three contractors working in parallel on the EVA System Phase A Study, focusing on Implications for Man-Systems Design. Overhead visuals are included for a mission results summary, space station EVA requirements and interface accommodations summary, human productivity study cross-task coordination, and advanced EVAS Phase A study implications for man-systems design. Articles are also included on subsea approach to work systems development and advanced EVA system design requirements.

  4. The ecosystem approach to health is a promising strategy in international development: lessons from Japan and Laos.

    PubMed

    Asakura, Takashi; Mallee, Hein; Tomokawa, Sachi; Moji, Kazuhiko; Kobayashi, Jun

    2015-02-16

    An ecological perspective was prominently present in the health promotion movement in the 1980s, but this seems to have faded. The burden of disease the developing world is facing cannot be addressed solely by reductionist approaches. Holistic approaches are called for that recognize the fundamentally interdependent nature of health and other societal, developmental, and ecosystem related factors in human communities. An ecosystem approach to human health (ecohealth) provides a good starting point to explore these interdependencies. Development assistance is often based on the assumption that developed countries can serve as models for developing ones. Japan has provided lavish assistance to Laos for example, much of it going to the development of transport networks. However, there is little sign that there is an awareness of the potentially negative environmental and health impacts of this assistance. We argue that the health consequences of environmental degradation are not always understood, and that developing countries need to consider these issues. The ecohealth approach is useful when exploring this issue. We highlight three implications of the ecohealth approach: (1) The WHO definition of health as a state of complete physical, mental and social well-being emphasized that health is more than the absence of disease. However, because this approach may involve an unattainable goal, we suggest that health should be defined in the ecosystem context, and the goal should be to attain acceptable and sustainable levels of health through enabling people to realize decent livelihoods, and to pursue their life purpose; (2) The increasing interconnectedness of ecosystems in a globalizing world requires an ethical approach that considers human responsibility for the global biosphere. Here, ecohealth could be a countervailing force to our excessive concentration on economy and technology; and (3) If ecohealth is to become a positive agent of change in the global health promotion movement, it will have to find a secure place in the educational curriculum. This article presents a brief case study of Japan's development assistance to Laos, and its environmental and health implications, as an illustration of the ecohealth approach. We highlight three implications of the ecohealth perspective.

  5. An Enterprising Approach to Regional Growth: Implications for Policy and the Role of VET--Support Document

    ERIC Educational Resources Information Center

    Garlick, Steve; Taylor, Michael; Plummer, Paul

    2007-01-01

    "An Enterprising Approach to Regional Growth: Implications for Policy and the Role of Vocational Education and Training" explores patterns of regional economic growth in Australia over the period 1984 to 2002 with the aim of identifying the drivers of variation in regional growth; the research also aimed to identify regional…

  6. A Genetic Approach to Identifying Signal Transduction Mechanisms Initiated by Receptors for TGF-B-Related Factors.

    DTIC Science & Technology

    1998-10-01

    resistant to TGF-ß-induced growth arrest suggest that both types of receptors are required for signaling (Boyd and Massague, 1989; Laiho et ah, 1990...II in TGF-ß- resistant cell mutants implicates both receptor types in signal transduction. J. Biol. Chem. 265, 18518-18524. Lechleider, R. J., de...I-1 « -J AD GRANT NUMBER DAMD17-94-J-4339 TITLE: A Genetic Approach to Identifying Signal Transduction Mechanisms Initiated by Receptors

  7. Discovery and structure-activity relationship of oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B.

    PubMed

    Liu, Gang; Szczepankiewicz, Bruce G; Pei, Zhonghua; Janowick, David A; Xin, Zhili; Hajduk, Philip J; Abad-Zapatero, Cele; Liang, Heng; Hutchins, Charles W; Fesik, Stephen W; Ballaron, Steve J; Stashko, Mike A; Lubben, Tom; Mika, Amanda K; Zinker, Bradley A; Trevillyan, James M; Jirousek, Michael R

    2003-05-22

    Protein Tyrosine phosphatase 1B (PTP1B) has been implicated as a key negative regulator of both insulin and leptin signaling pathways. Using an NMR-based screening approach with 15N- and 13C-labeled PTP1B, we have identified 2,3-dimethylphenyloxalylaminobenzoic acid (1) as a general, reversible, and competitive PTPase inhibitor. Structure-based approach guided by X-ray crystallography facilitated the development of 1 into a novel series of potent and selective PTP1B inhibitors occupying both the catalytic site and a portion of the noncatalytic, second phosphotyrosine binding site. Interestingly, oral biovailability has been observed in rats for some compounds. Furthermore, we demonstrated in vivo plasma glucose lowering effects with compound 12d in ob/ob mice.

  8. Variations in aseptic technique and implications for infection control.

    PubMed

    Aziz, Anne Marie

    Healthcare-acquired infections (HAIs) are a serious concern, costing the NHS 1 billion pounds a year and causing 5000 deaths annually despite increased funding. A contributing factor is the variety of aseptic techniques in use in different hospitals and even within a single hospital. These cause problems for healthcare workers as well as increasing the risk of HAI. This article examines a number of traditional approaches to aseptic technique, highlighting their differences and the implications for infection control. It concludes that improvement in aseptic technique could be achieved by implementation of a single unified approach to aseptic technique that can be standardized and audited annually, such as the aseptic non-touch technique (ANTT), which has been recommended for adoption throughout the UK. It ends with suggestions for measures that could be introduced and strengthened to improve aseptic technique, and ultimately reduce the rate of HAI.

  9. Attributes for MRB_E2RF1 Catchments by Major River Basins in the Conterminous United States: NLCD 2001 Imperviousness

    USGS Publications Warehouse

    Wieczorek, Michael; LaMotte, Andrew E.

    2010-01-01

    This tabular data set represents the mean percent impervious surface from the Imperviousness Layer of the National Land Cover Dataset 2001, (LaMotte and Wieczorek, 2010), compiled for every MRB_E2RF1 catchment of selected Major River Basins (MRBs, Crawford and others, 2006). The source data set represents imperviousness for the conterminous United States for 2001. The Imperviousness Layer of the National Land Cover Data Set for 2001 was produced through a cooperative project conducted by the Multi-Resolution Land Characteristics (MRLC) Consortium. The MRLC Consortium is a partnership of Federal agencies (http://www.mrlc.gov), consisting of the U.S. Geological Survey (USGS), the National Oceanic and Atmospheric Administration (NOAA), the U.S. Environmental Protection Agency (USEPA), the U.S. Department of Agriculture (USDA), the U.S. Forest Service (USFS), the National Park Service (NPS), the U.S. Fish and Wildlife Service (USFWS), the Bureau of Land Management (BLM), and the USDA Natural Resources Conservation Service (NRCS). The MRB_E2RF1 catchments are based on a modified version of the U.S. Environmental Protection Agency's (USEPA) ERF1_2 and include enhancements to support national and regional-scale surface-water quality modeling (Nolan and others, 2002;Brakebill and others, 2011). Data were compiled for every MRB_E2RF1 catchment for the conterminous United States covering New England and Mid-Atlantic (MRB1), South Atlantic-Gulf and Tennessee (MRB2), the Great Lakes, Ohio, Upper Mississippi, and Souris-Red-Rainy (MRB3), the Missouri (MRB4), the Lower Mississippi, Arkansas-White-Red, and Texas-Gulf (MRB5), the Rio Grande, Colorado, and the Great basin (MRB6), the Pacific Northwest (MRB7) river basins, and California (MRB8).

  10. Attributes for MRB_E2RF1 Catchments by Major River Basins in the Conterminous United States: NLCD 2001 Tree Canopy

    USGS Publications Warehouse

    Wieczorek, Michael; LaMotte, Andrew E.

    2010-01-01

    This tabular data set represents the mean percent tree canopy from the Canopy Layer of the National Land Cover Dataset 2001 (LaMotte and Wieczorek, 2010), compiled for every MRB_E2RF1 catchment of Major River Basins (MRBs, Crawford and others, 2006). The source data set represents tree canopy percentage for the conterminous United States for 2001. The Canopy Layer of the National Land Cover Data Set for 2001 was produced through a cooperative project conducted by the Multi-Resolution Land Characteristics (MRLC) Consortium. The MRLC Consortium is a partnership of Federal agencies (http://www.mrlc.gov), consisting of the U.S. Geological Survey (USGS), the National Oceanic and Atmospheric Administration (NOAA), the U.S. Environmental Protection Agency (USEPA), the U.S. Department of Agriculture (USDA), the U.S. Forest Service (USFS), the National Park Service (NPS), the U.S. Fish and Wildlife Service (USFWS), the Bureau of Land Management (BLM), and the USDA Natural Resources Conservation Service (NRCS). The MRB_E2RF1 catchments are based on a modified version of the U.S. Environmental Protection Agency's (USEPA) ERF1_2 and include enhancements to support national and regional-scale surface-water quality modeling (Nolan and others, 2002; Brakebill and others, 2011). Data were compiled for every MRB_E2RF1 catchment for the conterminous United States covering New England and Mid-Atlantic (MRB1), South Atlantic-Gulf and Tennessee (MRB2), the Great Lakes, Ohio, Upper Mississippi, and Souris-Red-Rainy (MRB3), the Missouri (MRB4), the Lower Mississippi, Arkansas-White-Red, and Texas-Gulf (MRB5), the Rio Grande, Colorado, and the Great basin (MRB6), the Pacific Northwest (MRB7) river basins, and California (MRB8).

  11. Asset Literacy Following Stroke: Implications for Disaster Resilience.

    PubMed

    O'Sullivan, Tracey L; Fahim, Christine; Gagnon, Elizabeth

    2017-10-17

    The World Stroke Organization "1 in 6" campaign aims to raise awareness that 1 in 6 persons will experience a stroke during their lifetime. With aging populations and improved survival rates, an increased number of survivors live with functional limitations and require supportive care. This has important implications for implementing an all-of-society approach to disaster risk reduction. In this study, we explore the assets that stroke survivors and caregivers consider useful in supporting their capacity to manage routine activities and independent living and to respond to a disaster. Transcripts from interviews with stroke survivors and caregivers were analyzed by use of content analysis. Assets were categorized into 4 classes: social, physical, energy, and personal characteristics and are presented as a household map. Emergent themes suggested that understanding how to mobilize assets is complicated yet essential for building resilience. Household resilience requires people have self-efficacy and motivation to move from awareness to action. The findings informed development of a conceptual model of asset literacy and household resilience following stroke. Interventions to enhance asset literacy can support an all-of-society approach to disaster risk reduction through awareness, empowerment, participation, innovation, and engagement. (Disaster Med Public Health Preparedness. 2017;page 1 of 9).

  12. The Case for a Market Consciousness in Continuing Education: Implications for Long-Range Curriculum Planning.

    ERIC Educational Resources Information Center

    Frandson, Phillip E.

    1981-01-01

    Provides a conceptual outline of marketing strategies that includes a Flexnerian approach to curriculum development. Concentrates on (1) the medical profession, especially the individual physician, and (2) the nation's large universities, with their science centers and medical schools. (Available from University of California Press, Berkeley, CA…

  13. Ten Commonalities of Suicide and Some Implications for Public Policy.

    ERIC Educational Resources Information Center

    Shneidman, Edwin S.

    This paper describes 10 common characteristics of suicide that pertain to suicide committed at any age. Each characteristic is defined and analyzed, with specific approaches to treatment identified. The 10 characteristics, based on clinical experience and the relevant work of others, are listed. The commonalities discussed include: (1) the common…

  14. The Neural Mechanisms of Word Order Processing Revisited: Electrophysiological Evidence from Japanese

    ERIC Educational Resources Information Center

    Wolff, Susann; Schlesewsky, Matthias; Hirotani, Masako; Bornkessel-Schlesewsky, Ina

    2008-01-01

    We present two ERP studies on the processing of word order variations in Japanese, a language that is suited to shedding further light on the implications of word order freedom for neurocognitive approaches to sentence comprehension. Experiment 1 used auditory presentation and revealed that initial accusative objects elicit increased processing…

  15. A Second Look at Maslow's Hierarchy of Basic Needs.

    ERIC Educational Resources Information Center

    White, Charles M.

    Implications of Maslow's Need Hierarchy are considered in this paper, along with possible qualifications to the suggested structure and potential effects of superimposing relative deprivation theory onto the hierarchy as an approach to adult education. The interfacing of needs and alternative structurings is discussed in terms of two theories: (1)…

  16. Learning Science by Engaging Religion: A Novel Two-Course Approach for Biology Majors

    ERIC Educational Resources Information Center

    Eisen, Arri; Huang, Junjian

    2014-01-01

    Many issues in science create individual and societal tensions with important implications outside the classroom. We describe one model that directly addresses such tensions by integrating science and religion in two parallel, integrated courses for science majors. Evaluation of the goals of the project--(1) providing students with strategies to…

  17. Language and Literacy in Workplace Education: Learning at Work. Language in Social Life Series.

    ERIC Educational Resources Information Center

    Mawer, Giselle; Fletcher, Lee; McCall, Julia; O'Grady, Catherine; Ong, Bee Jong

    Interweaving theory and commentary with case studies, this book explores a multifaceted approach to workplace education that develops workers' skills and integrates learning, language, and cross-cultural issues into work, communication, and management practices. Chapter 1 explores the changing world of work and implications for workforce skill…

  18. Telecommunications Technology and the Socialization of Black Americans: Issues, Concerns and Possibilities.

    ERIC Educational Resources Information Center

    Johnson, Robert C., III

    A study was made to explore and to assess the understanding and perceptions of communications technology held by the lay black community and black professional educators and to examine the implications of their perceptions and understanding for social policy. The methodological approach consisted of a: (1) black educational historiography; (2)…

  19. Lipopolysaccharide-induced early response genes in bovine peripheral blood mononuclear cells implicate GLG1/E-selectin as a key ligand–receptor interaction

    USDA-ARS?s Scientific Manuscript database

    This study uses a systems biology approach, integrating global gene expression information and knowledge of the regulatory events in cells to identify transcription networks controlling peripheral blood mononuclear cells’ (PBMCs) immune response to lipopolysaccharide (LPS) and to identify the molecu...

  20. Profiling Environmental Chemicals for Activity in the Antioxidant Response Element Signaling Pathway Using a High-Throughput Screening Approach

    EPA Science Inventory

    1 ABSTRACT 2 3 BACKGROUND: Oxidative stress has been implicated in the pathogenesis of a variety 4 of diseases ranging from cancer to neurodegeneration, highlighti.ng the need to identify 5 chemicals that can induce this effect. The antioxidant response element (ARE)...

  1. A multi-scale analysis of streamflow response to changes in evapotranspiration and soil hydrology in the Blue Ridge Mountains (Invited)

    NASA Astrophysics Data System (ADS)

    Price, K.; Jackson, C. R.

    2013-12-01

    A large amount of research exploring the relationship between watershed forest cover and streamflow quantity has been conducted in the southern Blue Ridge Mountains, particularly in association with the USFS Coweeta Hydrologic Laboratory and the Coweeta LTER. However, a clear answer to the question ';How does changing tree cover influence runoff?' has not yet emerged for guidance of policy and management. The southern Blue Ridge is the source of water reaching much of the drought-sensitive Southeastern US, and a firmer understanding of the complexities of this issue is critical for water resources management for millions of people and diverse aquatic habitats. When this question has been explored in mesoscale systems (10s to 100s km2), results indicate that watersheds with greater forest cover have greater baseflow. Associated work has shown that hydraulic conductivities in forest soils are nearly an order of magnitude greater than lawn and pasture soils in this region. Our interpretation has been that in these mesoscale systems, the compaction of soil associated with forest conversion to other land uses has played a bigger role than related changes in evapotranspiration (ET) in shaping watershed dynamics and the overall water budget. Particular influence has been seen in baseflows, we posit, due to reduced infiltration and recharge. However, nearly a century of research in small experimental watersheds at Coweeta has shown that forest ET substantially reduces streamflows, including baseflows, when soils are not substantially altered. At this smaller scale of observations, details of forest composition and species water use variability have been thoroughly considered, while in the mesoscale studies 'forest cover' is treated as regionally uniform. Current small-scale work at Coweeta has shown that hemlock decline and subsequent replacement with other species has changed the magnitude and seasonality of ET, which is detectible in streamflow quantity and timing. Here, we attempt to resolve the seemingly conflicting results from experimental watershed and mesoscale studies, and consider the implications for even larger systems more directly linked to policy and management. A singular focus on streamflow quantities ignores broader water quality considerations related to forest management and conversion. We explore the idea that the pronounced control of precipitation variability on streamflow variability in this region confounds the inference of the relative importance of other influences, such as ET and soil hydraulics, particularly at moderate levels of disturbance. We also consider the complexities of heterogeneous land use and geomorphology, which are inevitably encountered in larger watersheds. Finally, we suggest preliminary guidance and future research approaches to provide information to policy and management on the sensitivity of various systems to forest removal or species conversion, across a range of spatial scales.

  2. A Quantitative Corpus-Based Approach to English Spatial Particles: Conceptual Symmetry and Its Pedagogical Implications

    ERIC Educational Resources Information Center

    Chen, Alvin Cheng-Hsien

    2014-01-01

    The present study aims to investigate how conceptual symmetry plays a role in the use of spatial particles in English and to further examine its pedagogical implications via a corpus-based evaluation of the course books in senior high schools in Taiwan. More specifically, we adopt a quantitative corpus-based approach to investigate whether bipolar…

  3. An Intervention in Literacy in Three Pacific Nations: Implications of a Context Specific Approach to Co-Design

    ERIC Educational Resources Information Center

    Jesson, Rebecca N.; Spratt, Rebecca

    2017-01-01

    In this paper, we consider the implications of a commitment to acknowledging the role of context within a research practice partnership. We outline the approach to doing so within a design-based research intervention with 42 schools across three Pacific Island countries to improve literacy learning and language development. In doing so, the paper…

  4. The hydrologic implications of alternative prioritizations of landscape-scale geographically isolated wetlands conservation

    NASA Astrophysics Data System (ADS)

    Evenson, G. R.; Golden, H. E.; Lane, C.; Mclaughlin, D. L.; D'Amico, E.

    2016-12-01

    Geographically isolated wetlands (GIWs), defined as upland embedded wetlands, provide an array of ecosystem goods and services. Wetland conservation efforts aim to protect GIWs in the face of continued threats from anthropogenic activities. Given limited conservation resources, there is a critical need for methods capable of evaluating the watershed-scale hydrologic implications of alternative approaches to GIW conservation. Further, there is a need for methods that quantify the watershed-scale aggregate effects of GIWs to determine their regulatory status within the United States. We applied the Soil and Water Assessment Tool (SWAT), a popular watershed-scale hydrologic model, to represent the 1,700 km2 Pipestem Creek watershed in North Dakota, USA. We modified the model to incorporate an improved representation of GIW hydrologic processes via hydrologic response unit (HRU) redefinition and modifications to the model source code. We then used the model to evaluate the hydrologic effects of alternative approaches to GIW conservation prioritization by simulating the destruction/removal of GIWs by sub-classes defined by their relative position within the simulated fill-spill GIW network and their surface area characteristics. We evaluated the alternative conservation approaches as impacting (1) simulated streamflow at the Pipestem Creek watershed outlet; (2) simulated water-levels within the GIWs; and (3) simulated hydrologic connections between the GIWs. Our approach to modifying SWAT and evaluating alternative GIW conservation strategies may be replicated in different watersheds and physiographic regions to aid the development of GIW conservation priorities.

  5. Improving self-management of type 1 and type 2 diabetes.

    PubMed

    Phillips, Anne

    2016-01-06

    Diabetes is an increasingly common life-long condition, which has significant physical, psychological and behavioural implications for individuals. Self-management of type 1 and type 2 diabetes can be complex and challenging. A collaborative approach to care, between healthcare professionals and patients, is essential to promote self-management skills and knowledge to help patients engage in shared decision making and manage any difficulties associated with a diagnosis of diabetes.

  6. Advancement of Latent Trait Theory.

    DTIC Science & Technology

    1988-02-01

    if I am the principal investigator, I find it practically impossible to include and systematize all the important findings and implications within a...methods are described in [1.21. Two important features of the principal investigator’s approach are the following. (1) It does not assume any specific...were described in the preceding chapter, the maximum likelihood estimate 0 of ability 0 , and also f of the transformed ability r play important roles

  7. VEZF1 Elements Mediate Protection from DNA Methylation

    PubMed Central

    Strogantsev, Ruslan; Gaszner, Miklos; Hair, Alan; Felsenfeld, Gary; West, Adam G.

    2010-01-01

    There is growing consensus that genome organization and long-range gene regulation involves partitioning of the genome into domains of distinct epigenetic chromatin states. Chromatin insulator or barrier elements are key components of these processes as they can establish boundaries between chromatin states. The ability of elements such as the paradigm β-globin HS4 insulator to block the range of enhancers or the spread of repressive histone modifications is well established. Here we have addressed the hypothesis that a barrier element in vertebrates should be capable of defending a gene from silencing by DNA methylation. Using an established stable reporter gene system, we find that HS4 acts specifically to protect a gene promoter from de novo DNA methylation. Notably, protection from methylation can occur in the absence of histone acetylation or transcription. There is a division of labor at HS4; the sequences that mediate protection from methylation are separable from those that mediate CTCF-dependent enhancer blocking and USF-dependent histone modification recruitment. The zinc finger protein VEZF1 was purified as the factor that specifically interacts with the methylation protection elements. VEZF1 is a candidate CpG island protection factor as the G-rich sequences bound by VEZF1 are frequently found at CpG island promoters. Indeed, we show that VEZF1 elements are sufficient to mediate demethylation and protection of the APRT CpG island promoter from DNA methylation. We propose that many barrier elements in vertebrates will prevent DNA methylation in addition to blocking the propagation of repressive histone modifications, as either process is sufficient to direct the establishment of an epigenetically stable silent chromatin state. PMID:20062523

  8. Attributes for MRB_E2RF1 Catchments by Major River Basins in the Conterminous United States: NLCD 2001 Land Use and Land Cover

    USGS Publications Warehouse

    Wieczorek, Michael; LaMotte, Andrew E.

    2010-01-01

    This tabular data set represents the estimated area of land use and land cover from the National Land Cover Dataset 2001 (LaMotte, 2008), compiled for every MRB_E2RF1 catchment of the Major River Basins (MRBs, Crawford and others, 2006). The source data set represents land use and land cover for the conterminous United States for 2001. The National Land Cover Data Set for 2001 was produced through a cooperative project conducted by the Multi-Resolution Land Characteristics (MRLC) Consortium. The MRLC Consortium is a partnership of Federal agencies (http://www.mrlc.gov), consisting of the U.S. Geological Survey (USGS), the National Oceanic and Atmospheric Administration (NOAA), the U.S. Environmental Protection Agency (USEPA), the U.S. Department of Agriculture (USDA), the U.S. Forest Service (USFS), the National Park Service (NPS), the U.S. Fish and Wildlife Service (USFWS), the Bureau of Land Management (BLM), and the USDA Natural Resources Conservation Service (NRCS). The MRB_E2RF1 catchments are based on a modified version of the U.S. Environmental Protection Agency's (USEPA) ERF1_2 and include enhancements to support national and regional-scale surface-water quality modeling (Nolan and others, 2002; Brakebill and others, 2011). Data were compiled for every MRB_E2RF1 catchment for the conterminous United States covering the South Atlantic-Gulf and Tennessee (MRB2), the Great Lakes, Ohio, Upper Mississippi, and Souris-Red-Rainy (MRB3), the Missouri (MRB4), the Lower Mississippi, Arkansas-White-Red, and Texas-Gulf (MRB5) and the Pacific Northwest (MRB7) river basins.

  9. Theory and Methodology in Researching Emotions in Education

    ERIC Educational Resources Information Center

    Zembylas, Michalinos

    2007-01-01

    Differing theoretical approaches to the study of emotions are presented: emotions as private (psychodynamic approaches); emotions as sociocultural phenomena (social constructionist approaches); and a third perspective (interactionist approaches) transcending these two. These approaches have important methodological implications in studying…

  10. Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium.

    PubMed

    Hohman, Timothy J; Bush, William S; Jiang, Lan; Brown-Gentry, Kristin D; Torstenson, Eric S; Dudek, Scott M; Mukherjee, Shubhabrata; Naj, Adam; Kunkle, Brian W; Ritchie, Marylyn D; Martin, Eden R; Schellenberg, Gerard D; Mayeux, Richard; Farrer, Lindsay A; Pericak-Vance, Margaret A; Haines, Jonathan L; Thornton-Wells, Tricia A

    2016-02-01

    Late-onset Alzheimer disease (AD) has a complex genetic etiology, involving locus heterogeneity, polygenic inheritance, and gene-gene interactions; however, the investigation of interactions in recent genome-wide association studies has been limited. We used a biological knowledge-driven approach to evaluate gene-gene interactions for consistency across 13 data sets from the Alzheimer Disease Genetics Consortium. Fifteen single nucleotide polymorphism (SNP)-SNP pairs within 3 gene-gene combinations were identified: SIRT1 × ABCB1, PSAP × PEBP4, and GRIN2B × ADRA1A. In addition, we extend a previously identified interaction from an endophenotype analysis between RYR3 × CACNA1C. Finally, post hoc gene expression analyses of the implicated SNPs further implicate SIRT1 and ABCB1, and implicate CDH23 which was most recently identified as an AD risk locus in an epigenetic analysis of AD. The observed interactions in this article highlight ways in which genotypic variation related to disease may depend on the genetic context in which it occurs. Further, our results highlight the utility of evaluating genetic interactions to explain additional variance in AD risk and identify novel molecular mechanisms of AD pathogenesis. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. A muscle-specific knockout implicates nuclear receptor coactivator MED1 in the regulation of glucose and energy metabolism.

    PubMed

    Chen, Wei; Zhang, Xiaoting; Birsoy, Kivanc; Roeder, Robert G

    2010-06-01

    As conventional transcriptional factors that are activated in diverse signaling pathways, nuclear receptors play important roles in many physiological processes that include energy homeostasis. The MED1 subunit of the Mediator coactivator complex plays a broad role in nuclear receptor-mediated transcription by anchoring the Mediator complex to diverse promoter-bound nuclear receptors. Given the significant role of skeletal muscle, in part through the action of nuclear receptors, in glucose and fatty acid metabolism, we generated skeletal muscle-specific Med1 knockout mice. Importantly, these mice show enhanced insulin sensitivity and improved glucose tolerance as well as resistance to high-fat diet-induced obesity. Furthermore, the white muscle of these mice exhibits increased mitochondrial density and expression of genes specific to type I and type IIA fibers, indicating a fast-to-slow fiber switch, as well as markedly increased expression of the brown adipose tissue-specific UCP-1 and Cidea genes that are involved in respiratory uncoupling. These dramatic results implicate MED1 as a powerful suppressor in skeletal muscle of genetic programs implicated in energy expenditure and raise the significant possibility of therapeutical approaches for metabolic syndromes and muscle diseases through modulation of MED1-nuclear receptor interactions.

  12. Women at Midlife: Implications for Theories of Women's Adult Development.

    ERIC Educational Resources Information Center

    Lippert, Laurel

    1997-01-01

    Discusses research on midlife transitions in women and its implications for theories of women's adult development. Presents findings on menopause, the postparental period, and the roles of women at midlife. Offers several theoretical approaches in light of research findings and makes recommendations for future research. Suggests implications for…

  13. The CARIACO Ocean Time-Series: two decades of oceanographic observations to understand linkages between biogeochemistry, ecology, and long-term environmental variability.

    NASA Astrophysics Data System (ADS)

    Lorenzoni, L.; Muller-Karger, F. E.; Rueda-Roa, D. T.; Thunell, R.; Scranton, M. I.; Taylor, G. T.; benitez-Nelson, C. R.; Montes, E.; Astor, Y. M.; Rojas, J.

    2016-02-01

    The CARIACO Ocean Time-Series project, located in the Cariaco Basin off the coast of Venezuela, seeks to understand relationships between hydrography, primary production, community composition, microbial activity, particle fluxes, and element cycling in the water column, and how variations in these processes are preserved in sediments accumulating in this anoxic basin. CARIACO uses autonomous and shipboard measurements to understand ecological and biogeochemical changes and how these relate to regional and global climatic/ocean variability. CARIACO is a model for national ocean observing programs in Central/South America, and has been developed as a community facility platform with open access to all data (http://imars.marine.usf.edu/cariaco). Research resulting from this program has contributed to knowledge about the decomposition and cycling of particles, the biological pump, and to our understanding of the ecology and oceanography of oxygen minimum zones. Despite this basin being anoxic below 250m, remineralization rates of organic matter are comparable to those in well oxygenated waters. A dynamic microbial community significantly influences carbon and nutrient biogeochemical cycling throughout the water column. Since 1995, declining particulate organic carbon fluxes have been measured throughout the water column using sediment traps, likely in response to declining Chl-a concentrations and smaller phytoplankton which have replaced the larger taxa over the past decade. This community shift appears to be caused by regional changes in the physical regime. CARIACO also recorded marked long-term changes in surface and deep DIC in response to a combination of factors including surface water warming. The observations of CARIACO highlight the importance of a sustained, holistic approach to studying biodiversity, ecology and the marine carbon cycle to predict potential impacts of climate change on the ocean's ecosystem services and carbon sequestration efficiency.

  14. Acceptable health and priority weighting: Discussing a reference-level approach using sufficientarian reasoning.

    PubMed

    Wouters, S; van Exel, N J A; Rohde, K I M; Vromen, J J; Brouwer, W B F

    2017-05-01

    Health care systems are challenged in allocating scarce health care resources, which are typically insufficient to fulfil all health care wants and needs. One criterion for priority setting may be the 'acceptable health' approach, which suggests that society may want to assign higher priority to health benefits in people with "unacceptable" than in people with "acceptable" health. A level of acceptable health then serves as a reference point for priority setting. Empirical research has indicated that people may be able and willing to define health states as "unacceptable" or "acceptable", but little attention has been given to the normative implications of evaluating health benefits in relation to a reference level of acceptable health. The current paper aims to address this gap by relating insights from the distributive justice literature, i.e. the sufficientarian literature, to the acceptable health approach, as we argue that these approaches are related. We specifically focus on the implications of an 'acceptability' approach for priority weighting of health benefits, derived from sufficientarian reasoning and debates, and assess the moral implications of such weighting. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Psychosocial stress and cardiovascular disease. Part 3: Clinical and policy implications of research on the transcendental meditation program.

    PubMed

    Walton, Kenneth G; Schneider, Robert H; Salerno, John W; Nidich, Sanford I

    2005-01-01

    Cardiovascular disease (CVD) remains the leading cause of death in the United States today and a major contributor to total health care costs. Psychosocial stress has been implicated in CVD, and psychosocial approaches to primary and secondary prevention are gaining research support. This third article in the series on psychosocial stress and CVD continues the evaluation of one such approach, the Maharishi Transcendental Meditation program, a psychophysiological approach from the Vedic tradition that is systematically taught by qualified teachers throughout the world. Evidence suggests not only that this program can provide benefits in prevention but also that it may reduce CVD-related and other health care expenses. On the basis of data from the studies available to date, the Transcendental Meditation program may be responsible for reductions of 80% or greater in medical insurance claims and payments to physicians. This article evaluates the implications of research on the Transcendental Meditation program for health care policy and for large-scale clinical implementation of the program. The Transcendental Meditation program can be used by individuals of any ethnic or cultural background, and compliance with the practice regimen is generally high. The main steps necessary for wider adoption appear to be: (1) educating health care providers and patients about the nature and expected benefits of the program, and (2) adjustments in public policies at the state and national levels to allow this program to be included in private and public health insurance plans.

  16. Bolzano`s Approach to the Paradoxes of Infinity: Implications for Teaching

    NASA Astrophysics Data System (ADS)

    Waldegg, Guillermina

    2005-08-01

    In this paper we analyze excerpts of Paradoxes of the Infinite, the posthumous work of Bernard Bolzano (1781-1848), in order to show that Georg Cantor‘s (1845-1918) approach to the problem of defining actual mathematical infinity is not the most natural. In fact, Bolzano‘s approach to the paradoxes of infinity is more intuitive, while remaining internally coherent. Bolzano‘s approach, however, had limitations. We discuss implications for teaching, which include a better understanding of the responses of students to situations involving actual mathematical infinity, for it is possible to draw a kind of parallel between these responses and Bolzano‘s reasoning.

  17. The stress-reward-mentalizing model of depression: An integrative developmental cascade approach to child and adolescent depressive disorder based on the research domain criteria (RDoC) approach.

    PubMed

    Luyten, Patrick; Fonagy, Peter

    2017-10-09

    The Research Domain Criteria (RDoC) propose a much-needed change in approach to the study of vulnerability factors implicated in mental disorders, shifting away from a categorical, disease-oriented model to a dimensional approach that focuses on underlying systems implicated in psychopathology. In this paper we illustrate this approach with a focus on the emergence of depression in childhood and adolescence. Based on evolutionary biological and developmental psychopathology considerations, we present an integrative developmental cascade model of depression that essentially suggests that depression emerges out of a three-pronged series of interacting impairments in the domains of stress regulation, reward, and mentalizing. We discuss the relation of these impairments to the five domains proposed by RDoC. We also focus on how this model may explain in large part the marked comorbidity of depression with other psychiatric disorders, as well as with functional somatic and somatic disorders. Limitations of this theoretical approach are discussed, as well as implications for the development, evaluation, and dissemination of interventions aimed at preventing or treating depression. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Approach--avoidance motivation and information processing: a cross-cultural analysis.

    PubMed

    Hamamura, Takeshi; Meijer, Zita; Heine, Steven J; Kamaya, Kengo; Hori, Izumi

    2009-04-01

    Much recent research suggests that North Americans more frequently experience approach motivations and East Asians more frequently experience avoidance motivations. The current research explores some cognitive implications of this cultural difference. North Americans should be more attentive to approach-oriented information, whereas East Asians should be more attentive to avoidance-oriented information. Three studies confirmed this hypothesis. When asked to recall information framed in either approach or avoidance terms, a predicted interaction between culture and information frame was observed (Study 1 and 2). Moreover, analyses of consumer book reviews found that among reviews that were rated as helpful, approach-focused content was more prevalent in American reviews compared to Japanese reviews, in which avoidance-focused content was more prevalent (Study 3). Findings from the current research add to the growing literature of cross-cultural research on approach-avoidance motivations.

  19. ALK and ROS1 as targeted therapy paradigms and clinical implications to overcome crizotinib resistance

    PubMed Central

    Li, Nan; Zhang, Yong; Jing, Pengyu; Chang, Ning; Wu, Jianxiong; Ren, Xinling; Zhang, Jian

    2016-01-01

    During the past decade, more than 10 targetable oncogenic driver genes have been validated in non-small cell lung cancer (NSCLC). Anaplastic lymphoma kinase (ALK) and ROS1 kinase are two new driver genes implicated in ALK- and ROS1-rearranged NSCLC. Inhibition of ALK and ROS1 by crizotinib has been reported to be highly effective and well tolerated in these patients. However, resistance to crizotinib emerges years after treatment, and increasing efforts have been made to overcome this issue. Here, we review the biology of ALK and ROS1 and their roles in cancer progression. We also summarize the ongoing and completed clinical trials validating ALK and ROS1 as targets for cancer treatment. In the last section of the review, we will discuss the molecular mechanisms of crizotinib resistance and focus approaches to overcome it. This review describes an exciting new area of research and may provide new insights for targeted cancer therapies. PMID:26802023

  20. Financial Implications of the Extended School Year.

    ERIC Educational Resources Information Center

    San Diego Unified School District, CA. Administrative Research Dept.

    This report considers the costs of three types of extended school year programs--all modifications of the quarter system--and compares these costs to the regular program. Compared against the traditional approach are: (1) a quarter system in which students attend three quarters a year and are off one quarter, meaning that 75% of all students are…

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