76 FR 59502 - Establishment of Class E Airspace; Gordonsville, VA
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-27
... at Gordonsville, VA, to accommodate the new Standard Instrument Approach Procedures serving Gordonsville Municipal Airport. This action enhances the safety and airspace management of Instrument Flight... approach procedures developed for Gordonsville Municipal Airport. This action is necessary for the safety...
76 FR 55232 - Establishment of Class E Airspace; Copperhill, TN
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-07
...) Standard Instrument Approach Procedures serving Martin Campbell Field Airport. This action enhances the safety and airspace management of Instrument Flight Rules (IFR) operations within the National Airspace... Positioning System (GPS) Standard Instrument Approach Procedures developed for Martin Campbell Field Airport...
76 FR 14802 - Establishment of Class E Airspace; Lancaster, NH
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-18
... Standard Instrument Approach Procedure (SIAP) serving the Weeks Medical Center Heliport. This action enhances the safety and airspace management of Instrument Flight Rules (IFR) operations within the National... required to support the special standard instrument approach procedures developed for Weeks Medical Center...
76 FR 14801 - Establishment of Class E Airspace; Colebrook, NH
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-18
... Standard Instrument Approach Procedure (SIAP) serving the Upper Connecticut Valley Hospital Heliport. This action enhances the safety and airspace management of Instrument Flight Rules (IFR) operations within the... approach procedures developed for Upper Connecticut Valley Hospital Heliport. This action is necessary for...
76 FR 52230 - Establishment of Class E Airspace; Forest, VA
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-22
... Instrument Approach Procedures serving New London Airport. This action enhances the safety and airspace management of Instrument Flight Rules (IFR) operations within the National Airspace System. DATES: Effective... to support the new RNAV GPS standard instrument approach procedures developed for New London Airport...
77 FR 19076 - Establishment of Class E Airspace; Marion, AL
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-30
... Instrument Approach Procedures serving Vaiden Field. This action enhances the safety and airspace management... accommodate the new RNAV GPS Standard Instrument Approach Procedures developed for Vaiden Field. This action is necessary for the safety and management of IFR operations at the airport. The FAA has determined...
76 FR 45478 - Proposed Establishment of Class E Airspace; Nahunta, GA
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-29
...) Global Positioning System (GPS) Standard Instrument Approach Procedures serving the Brantley County...) operations within the National Airspace System. DATES: Comments must be received on or before September 12... distribution System, which describes the application procedure. [[Page 45479
76 FR 45479 - Proposed Establishment of Class E Airspace; Bumpass, VA
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-29
...) Global Positioning System (GPS) Standard Instrument Approach Procedures serving Lake Anna Airport. This... within the National Airspace System. DATES: Comments must be received on or before September 12, 2011... distribution System, which describes the application procedure. The Proposal The FAA is considering an...
78 FR 72008 - Establishment of Class E Airspace; Aliceville, AL
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-02
...) Standard Instrument Approach Procedure (SIAP) serving George Downer Airport. This action enhances the safety and management of Instrument Flight Rules (IFR) operations at the airport. DATES: Effective 0901..., providing the controlled airspace required to accommodate the new RNAV (GPS) Standard Instrument Approach...
New Horizons in Organizational Stress Prevention Approaches.
ERIC Educational Resources Information Center
McGaffey, Thomas N.
1978-01-01
Discusses and describes some active Employee Assistance Programs (EAPs). An EAP is a stress intervention program that, when combined with other stress prevention procedures, can serve as an effective base for developing a comprehensive managerial system for combating organizational stress. (Author/IRT)
Procedures for increasing the use of car pools for work trips.
DOT National Transportation Integrated Search
1979-01-01
This report describes methods and techniques that could be used to increase the use of car pools in Virginia. Two approaches are described. The first employs those methods that serve as an incentive for persons to form car pools, such as preferential...
76 FR 34196 - Proposed Establishment of Class E Airspace; Forest, VA
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-13
...) Global Positioning System (GPS) Standard Instrument Approach Procedures serving New London Airport. This action would enhance the safety and airspace management of Instrument Flight Rules (IFR) operations...; Airspace Docket No. 11-AEA-11) and be submitted in triplicate to the Docket Management System (see...
78 FR 14473 - Proposed Establishment of Class E Airspace; Sanibel, FL
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-06
...) Global Positioning System (GPS) special Standard Instrument Approach Procedure (SIAP) serving Sanibel Island Heliport. This action would enhance the safety and airspace management of Instrument Flight Rules...; Airspace Docket No. 12-ASO-18) and be submitted in triplicate to the Docket Management System (see...
78 FR 52111 - Proposed Establishment of Class E Airspace; Aliceville, AL
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-22
... (RNAV) Global Positioning System (GPS) Standard Instrument Approach Procedure (SIAP) serving George Downer Airport. This action would enhance the safety and airspace management of Instrument Flight Rules...; Airspace Docket No. 13-ASO-7) and be submitted in triplicate to the Docket Management System (see ADDRESSES...
78 FR 48080 - Proposed Establishment of Class E Airspace; Magee, MS
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-07
...) Global Positioning System (GPS) Standard Instrument Approach Procedure (SIAP) serving Magee Municipal...) operations within the National Airspace System. DATES: Comments must be received on or before September 23... No. 13-ASO-8) and be submitted in triplicate to the Docket Management System (see ADDRESSES section...
ERIC Educational Resources Information Center
Tasie, George O.
2010-01-01
Total quality management (TQM) strives to improve organizational functioning by carefully studying the interface between an organization's mission, values, vision, policies and procedures, and the consumer that the organization serves. Central to this approach to revitalizing economic institutions is the importance placed on client satisfaction.…
ERIC Educational Resources Information Center
Delisle, Jason
2007-01-01
This report argues that advance appropriations serve no functional purpose for schools, but they create a loss of transparency, comparability, and simplicity in federal education budgeting. It allocates spending before future budgets have been established. The approach was originally used to skirt spending limits and budget procedures in place…
Reforming the Discipline Management Process in Schools: An Alternative Approach to Zero Tolerance
ERIC Educational Resources Information Center
Kajs, Lawrence T.
2006-01-01
There is a need for educational reform of zero tolerance policies in school disciplinary management procedures. Zero tolerance policies are rigid mandates of predetermined consequences for specific student misconduct. Common sense and fairness are not necessarily served by the application of inflexible disciplinary rules that do not address the…
ERIC Educational Resources Information Center
Gürses, Nedim; Demiray, Emine
2009-01-01
In like manner as conventional education and teaching approaches distance education tends to model the same procedures. Indeed, formerly enriched on printed material served as a primary source. However, thanks to the developments in technology and evolution in education, computerised information has made inroads in distance education programmes.…
A Study of the Feasibility of Marketing Programming for Educational R & D Products.
ERIC Educational Resources Information Center
Sikorski, Linda A.; Hutchins, C. L.
This document argues the need for improved procedures for planning educational change. Specifically, it argues for a marketing approach which involves starting with the real needs of a particular population and planning a coordinated set of products and programs to serve those needs. The authors focus on using marketing concepts and techniques to…
ERIC Educational Resources Information Center
Gurses, Nedim; Demiray, Emine
2009-01-01
In like manner as conventional education and teaching approaches distance education tends to model the same procedures. Indeed, formerly enriched on printed material served as a primary source. However, thanks to the developments in technology and evolution in education, computerised information has made inroads in distance education programmes.…
31 CFR 317.3 - Procedure for qualifying and serving as issuing agent.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Procedure for qualifying and serving as issuing agent. 317.3 Section 317.3 Money and Finance: Treasury Regulations Relating to Money and... GOVERNING AGENCIES FOR ISSUE OF UNITED STATES SAVINGS BONDS § 317.3 Procedure for qualifying and serving as...
Adaptive management: Chapter 1
Allen, Craig R.; Garmestani, Ahjond S.; Allen, Craig R.; Garmestani, Ahjond S.
2015-01-01
Adaptive management is an approach to natural resource management that emphasizes learning through management where knowledge is incomplete, and when, despite inherent uncertainty, managers and policymakers must act. Unlike a traditional trial and error approach, adaptive management has explicit structure, including a careful elucidation of goals, identification of alternative management objectives and hypotheses of causation, and procedures for the collection of data followed by evaluation and reiteration. The process is iterative, and serves to reduce uncertainty, build knowledge and improve management over time in a goal-oriented and structured process.
Allen, Craig R.; Garmestani, Ahjond S.
2015-01-01
Adaptive management is an approach to natural resource management that emphasizes learning through management where knowledge is incomplete, and when, despite inherent uncertainty, managers and policymakers must act. Unlike a traditional trial and error approach, adaptive management has explicit structure, including a careful elucidation of goals, identification of alternative management objectives and hypotheses of causation, and procedures for the collection of data followed by evaluation and reiteration. The process is iterative, and serves to reduce uncertainty, build knowledge and improve management over time in a goal-oriented and structured process.
Acquisition Handbook - Update. Comprehensive Approach to Reusable Defensive Software (CARDS)
1994-03-25
designs, and implementation components (source code, test plans, procedures and results, and system/software documentation). This handbook provides a...activities where software components are acquired, evaluated, tested and sometimes modified. In addition to serving as a facility for the acquisition and...systems from such components [1]. Implementation components are at the lowest level and consist of: specifications; detailed designs; code, test
Wannagat, Severin; Loehr, Lena; Lask, Sebastian; Völk, Katharina; Karaköse, Tamer; Özcelik, Cemil; Mügge, Andreas; Wutzler, Alexander
2018-04-01
Catheter ablation is performed under fluoroscopic guidance. Reduction of radiation dose for patients and staff is emphasized by current recommendations. Previous studies have shown that lower operator experience leads to increased radiation dose. On the other hand, less experienced operators may depend even more on fluoroscopic guidance. Our study aimed to evaluate feasibility and efficacy of a non-fluoroscopic approach in different training levels. From January 2017, a near-zero fluoroscopy approach was established in two centers. Four operators (beginner, 1st year fellow, 2nd year fellow, expert) were instructed to perform the complete procedure with the use of a 3-D mapping system without fluoroscopy. A historical cohort that underwent procedures with fluoroscopy use served as control group. Dose area product (DPA), procedure duration, acute procedural success, and complications were compared between the groups and for each operator. Procedures were performed in 157 patients. The first 100 patients underwent procedures with fluoroscopic guidance, the following 57 procedures were performed with the near-zero fluoroscopy approach. The results show a significant reduction in DPA for all operators immediately after implementation of the near-zero fluoroscopy protocol (control 637 ± 611 μGy/m 2 ; beginner 44.1 ± 79.5 μGy/m 2 , p = 0.002; 1st year fellow 24.3 ± 46.4.5 μGy/m 2 , p = 0.001; 2nd year fellow 130.3 ± 233.3 μGy/m 2 , p = 0.003; expert 9.3 ± 37.4 μGy/m 2 , P < 0.001). Procedure duration, acute success, and complications were not significantly different between the groups. Our results show a 90% reduction of DPA shortly after implementation of a near-zero fluoroscopy approach in interventional electrophysiology even in operators in training.
32 CFR 516.77 - Procedures for exemption.
Code of Federal Regulations, 2010 CFR
2010-07-01
... PUBLIC RELATIONS LITIGATION Soldiers Summoned To Serve on State and Local Juries § 516.77 Procedures for exemption. (a) Active duty soldiers served with a summons to serve on a state or local jury will promptly... responsible state or local officials whenever a soldier summoned for jury duty is exempt. The notification...
Navigation errors encountered using weather-mapping radar for helicopter IFR guidance to oil rigs
NASA Technical Reports Server (NTRS)
Phillips, J. D.; Bull, J. S.; Hegarty, D. M.; Dugan, D. C.
1980-01-01
In 1978 a joint NASA-FAA helicopter flight test was conducted to examine the use of weather-mapping radar for IFR guidance during landing approaches to oil rig helipads. The following navigation errors were measured: total system error, radar-range error, radar-bearing error, and flight technical error. Three problem areas were identified: (1) operational problems leading to pilot blunders, (2) poor navigation to the downwind final approach point, and (3) pure homing on final approach. Analysis of these problem areas suggests improvement in the radar equipment, approach procedure, and pilot training, and gives valuable insight into the development of future navigation aids to serve the off-shore oil industry.
Barabasz, Arreed F; Barabasz, Marianne; Watkins, John G
2012-01-01
An abbreviated description of our single-session 5- to 6-hour procedure is provided. In contrast to trauma reframing approaches, such as cognitive processing therapy (CPT) or traditional psychoanalytic interventions, our manualized procedure rapidly demystifies subconscious processes, making them accessible and understandable by the patient. The therapist's supportive ego strength is integrated into the intense repeated emotional and physiological releases of the traumatized ego states. The abreactive component of this 5-phase procedure exhausts the bound-up psychological and physiological reactions but also serves to quickly overcome the trauma and to restructure the personality. The patient becomes empowered to release the trauma memories and to emerge with the ability to be adaptive, assertive, giving, strong, and able to express anger appropriately yet be caring with family/friends.
Hébert, Tiffany Michele; Maleki, Sara; Vasovic, Ljiljana V; Arnold, Jeffrey L; Steinberg, Jacob J; Prystowsky, Michael B
2014-03-01
Pathology residency training programs should aim to teach residents to think beyond the compartmentalized data of specific rotations and synthesize data in order to understand the whole clinical picture when interacting with clinicians. To test a collaborative autopsy procedure at Montefiore Medical Center (Bronx, New York), linking residents and attending physicians from anatomic and clinical pathology in the autopsy process from the initial chart review to the final report. Residents consult with clinical pathology colleagues regarding key clinical laboratory findings during the autopsy. This new procedure serves multiple functions: creating a team-based, mutually beneficial educational experience; actively teaching consultative skills; and facilitating more in-depth analysis of the clinical laboratory findings in autopsies. An initial trial of the team-based autopsy system was done from November 2010 to December 2012. Residents were then surveyed via questionnaire to evaluate the frequency and perceived usefulness of clinical pathology autopsy consultations. Senior residents were the most frequent users of clinical pathology autopsy consultation. The most frequently consulted services were microbiology and chemistry. Eighty-nine percent of the residents found the clinical pathology consultation to be useful in arriving at a final diagnosis and clinicopathologic correlation. The team-based autopsy is a novel approach to integration of anatomic and clinical pathology curricula at the rotation level. Residents using this approach develop a more holistic approach to pathology, better preparing them for meaningful consultative interaction with clinicians. This paradigm shift in training positions us to better serve in our increasing role as arbiters of outcomes measures in accountable care organizations.
Binnie, James
2018-04-01
Although the article by Scott rightly questions the dynamics of the Improving Access to Psychological Therapies system and re-examines the recovery rates, finding quite shocking results, his recommendations are ultimately flawed. There is a strong critique of the diagnostic procedures in Improving Access to Psychological Therapies services, but the answer is not to diagnose more rigorously and to adhere more strictly to a manualised approach to psychotherapy. The opposite may be required. Alternatives to the medical model of distress offer a less stigmatising and more human approach to helping people with their problems. Perhaps psychological therapists and the people they work alongside would be better served by a psychological approach rather than a psychiatric one.
Olsen, J; Spilger, S; Windisch, T
1995-05-01
To determine whether family members of recently deceased emergency department patients would consent to the performance of a cricothyrotomy on the deceased for educational purposes. Prospective study. Suburban tertiary care teaching hospital. Family members of 51 patients older than 18 years who were pronounced dead in the ED from atraumatic causes. Family members were approached by an attending physician for consent to perform a cricothyrotomy as a learning opportunity for physicians on their recently deceased family members. If consent was given, the procedure was performed by an emergency medicine resident physician under the attending physician's supervision. Of 51 deaths, 20 families (39%) consented to postmortem cricothyrotomy, 23 families (45%) refused consent, and 8 families (16%) were too distraught to be approached for consent. All 20 families that consented to the procedure were white, with little representation from other ethnic groups. Although there are difficulties in obtaining consent to perform invasive procedures on the recently deceased in the ED for educational purposes, our study demonstrates that many families will consent to such procedures if adequate information and explanation are provided. The results of this study may not be applicable to institutions serving patients with different cultural and ethnic backgrounds.
The PrOSTE: identifying key components of effective procedural teaching.
McSparron, Jakob I; Ricotta, Daniel N; Moskowitz, Ari; Volpicelli, Frank M; Roberts, David H; Schwartzstein, Richard M; Huang, Grace C
2015-02-01
Novel approaches for faculty development and assessment of procedural teaching skills are needed to improve the procedural education of trainees. The Objective Structured Teaching Exercise (OSTE) entails a simulated encounter in which faculty are observed teaching a standardized student and has been used to evaluate teaching skills. Use of an OSTE to assess the teaching of central venous catheterization has not been reported. The purpose of this study was to develop a procedural OSTE for subclavian central venous catheter (CVC) insertion and to determine specific aspects of procedural teaching associated with improved skills in novices. Critical care faculty/fellows taught a standardized student to insert a CVC in a simulator. We assessed the instructor's teaching skills using rating scales to generate a procedural teaching score. After this encounter, the instructor taught novice medical students to place CVCs in simulators. Novices then independently placed catheters in simulators and were evaluated by trained observers using a checklist. Generalized estimating equations were used to examine the correlation between specific teaching behaviors and the novices' skills in CVC placement. We recruited 10 participants to serve as teachers and 30 preclinical medical students to serve as novice learners. The overall mean procedural teaching score was 85.5 (±15.4). Improved student performance was directly related to the degree to which the teacher "provided positive feedback" (β = 1.53, SE = 0.44, P = 0.001), "offered learner suggestions for improvement" (β = 1.40, SE = 0.35, P < 0.001), and "demonstrated the procedure in a step-by-step manner" (β = 2.50, SE = 0.45, P < 0.001). There was no significant correlation between total scores and student skills (β = 0.06, SE = 0.46, P = 0.18). The OSTE is a standardized method to assess procedural teaching skills. Our findings suggest that specific aspects of procedural teaching should be emphasized to ensure effective transfer of psychomotor skills to trainees.
The purpose of this SOP is to describe the procedures undertaken to convert servings to kilograms for each food item used in the Diet Diary questionnaire. This SOP uses data that have been properly coded and certified with appropriate QA/QC procedures by the University of Arizon...
Assuring long-term reliability of concentrator PV systems
NASA Astrophysics Data System (ADS)
McConnell, R.; Garboushian, V.; Brown, J.; Crawford, C.; Darban, K.; Dutra, D.; Geer, S.; Ghassemian, V.; Gordon, R.; Kinsey, G.; Stone, K.; Turner, G.
2009-08-01
Concentrator PV (CPV) systems have attracted significant interest because these systems incorporate the world's highest efficiency solar cells and they are targeting the lowest cost production of solar electricity for the world's utility markets. Because these systems are just entering solar markets, manufacturers and customers need to assure their reliability for many years of operation. There are three general approaches for assuring CPV reliability: 1) field testing and development over many years leading to improved product designs, 2) testing to internationally accepted qualification standards (especially for new products) and 3) extended reliability tests to identify critical weaknesses in a new component or design. Amonix has been a pioneer in all three of these approaches. Amonix has an internal library of field failure data spanning over 15 years that serves as the basis for its seven generations of CPV systems. An Amonix product served as the test CPV module for the development of the world's first qualification standard completed in March 2001. Amonix staff has served on international standards development committees, such as the International Electrotechnical Commission (IEC), in support of developing CPV standards needed in today's rapidly expanding solar markets. Recently Amonix employed extended reliability test procedures to assure reliability of multijunction solar cell operation in its seventh generation high concentration PV system. This paper will discuss how these three approaches have all contributed to assuring reliability of the Amonix systems.
Berrocal, I; Peix, A; Mut, F; Shaw, L J; Karthikeyan, G; Estrada Lobato, E; Paez, D
2018-05-16
Across Latin American and Caribbean countries, cardiovascular disease and especially ischemic heart disease is currently the main cause of death both in men and in women. For most Latin American and Caribbean countries, public and community health efforts aim to define care strategies which are both clinically and cost effective and promote primary and secondary prevention, resulting in improved patient outcomes. The optimal approach to deal with acute events such as ST-elevation myocardial infarction (STEMI) is a matter of controversy; however, there is an expanding role for assessing residual ischemic burden in STEMI patients following primary percutaneous coronary intervention. Although randomized clinical trials have established the value of staged fractional flow reserve-guided revascularization, the use of noninvasive functional imaging modalities may play a similar role at a much lower cost. For LAC, available stress imaging techniques could be applied to define residual ischemia in the non-infarct related artery and to target revascularization in a staged procedure after primary percutaneous coronary intervention The use of nuclear cardiac imaging, supported by its relatively wide availability, moderate cost, and robust quantitative capabilities, may serve to guide effective care and to reduce subsequent cardiac events in patients with coronary artery disease. This noninvasive approach may avert potential safety issues with repeat and lengthy invasive procedures, and serve as a baseline for subsequent follow-up stress testing following the index STEMI event. This consensus document was devised from an expert panel meeting of the International Atomic Energy Agency, highlighting available evidence with a focus on the utility of stress myocardial perfusion imaging in post-STEMI patients. The document could serve as guidance to the prudent and appropriate use of nuclear imaging for targeting therapeutic management and avoiding unnecessary invasive procedures within Latin American and Caribbean countries, where resources could be scarce. Copyright © 2018. Publicado por Elsevier España, S.L.U.
A System Approach to Navy Medical Education and Training. Appendix 16. Aviation Technician.
1974-08-31
PHYSICAL/EMCTICNAL RESPONSE Tn ITREATMENT/DIAGNOSTIC PROCEDURES 5 IrSERVE/REPOPT SYMPTO4S OF SIDE EFFECTS TO TREATENT/MEOICATION 6 ICHECK TEXTURE OF...SKIN, E.G. DRY, OILY, SCALY 7 ICHECK COLOR OF SKIN, E.G. CYANOSIS, BLANCHING, JAUNPICE, MOTTLING 8 ICHECK TEMPERATURE OF SKIN j 9 IPERFORM...CIRCULATION CHECK, E.G. COLOR, PULSE, TEmPERATUrE OF ISKIN, CAPILLARY RETURN 10 ICHECK SKIN FOR ABNORMAL CONDITIONS, E.G. PPESSURE SORES, IBRUISES, NEEDLE MARKS
Approaches to child protection case management for cases involving people with disabilities.
Lightfoot, Elizabeth B; LaLiberte, Traci L
2006-04-01
This exploratory study examines the delivery of child protection services by county child protection agencies involving cases with a family member with a disability. Telephone surveys were conducted with the directors or their designees of 89% of the child protection agencies in a Midwestern state. Respondents were asked about the policies and/or procedures for approaching cases involving a person with a disability and the barriers and strengths agencies have in serving people with disabilities. Only 6.7% of respondents reported their agency had a written policy related to serving persons with a disability. There were 18 different approaches to serving clients with a disability within child protection, with the most common being informally teaming for information, dual case assignment, and teaming with an outside consultant. Five counties had specialty workers who were experts in both child protection and disability. Barriers reported varied between rural and non-rural counties, with the most important barriers being lack of resources, lack of knowledge regarding disabilities, systems conflicts, and rural issues, such as lack of providers and lack of transportation. Strengths included accessing and coordinating services, individualizing services, good collaboration and creativity. While few county agencies had any written policies, both formal and informal collaboration is happening at the individual level. The lack of standardization in providing services indicates a need for more attention to issues regarding disability within child protection, including more training for workers, the development of models of collaborative case management and the removal of systemic barriers.
Mitchell, Jean M; Carey, Kathleen
2016-02-01
Ambulatory surgery centers (ASCs) are freestanding facilities that specialize in surgical and diagnostic procedures that do not require an overnight stay. While it is generally assumed that ASCs are less costly than hospital outpatient surgery departments, there is sparse empirical evidence regarding their relative production costs. To estimate ASC production costs using financial and claims records for procedures performed by surgery centers that specialize in gastroenterology procedures (colonoscopy and endoscopy). We estimate production costs in ASCs that specialize in gastroenterology procedures using financial cost and patient discharge data from Pennsylvania for the time period 2004-2013. We focus on the 2 primary procedures (colonoscopies and endoscopies) performed at each ASC. We use our estimates to predict average costs for each procedure and then compare predicted costs to Medicare ACS payments for these procedures. Comparisons of the costs of each procedure with 2013 national Medicare ASC payment rates suggest that Medicare payments exceed production costs for both colonoscopy and endoscopy. This study demonstrated that it is feasible to estimate production costs for procedures performed in freestanding surgery centers. The procedure-specific cost estimates can then be compared with ASC payment rates to ascertain if payments are aligned with costs. This approach can serve as an evaluation template for CMS and private insurers who are concerned that ASC facility payments for specific procedures may be excessive.
NOTES: a review of the technical problems encountered and their solutions.
Mintz, Yoav; Horgan, Santiago; Cullen, John; Stuart, David; Falor, Eric; Talamini, Mark A
2008-08-01
Natural orifice translumenal endoscopic surgery (NOTES) is currently investigated and developed worldwide. In the past few years, multiple groups have confronted this challenge. Many technical problems are encountered in this technique due to the currently available tools for this approach. Some of the unique technical problems in NOTES include: blindly performed primary incisions; uncontrolled pneumoperitoneal pressure; no support for the endoscope in the abdominal cavity; inadequate vision; insufficient illumination; limited retraction and exposure; and the complexity of suturing and performing a safe anastomosis. In this paper, we review the problems encountered in NOTES and provide possible temporary solutions. Acute and survival studies were performed on 15 farm pigs. The hybrid technique approach (i.e., endoscopic surgery with the aid of laparoscopic vision) was performed in all cases. Procedures performed included liver biopsies, bilateral tubal ligation, oophprectomy, cholecystectomy, splenectomy and small bowel resection, and anastomosis. All attempted procedures were successfully performed. New methods and techniques were developed to overcome the technical problems. Closure of the gastrotomy was achieved by T-bar sutures and by stapler closure of the stomach incision. Small bowel anastomosis was achieved by the dual-lumen NOTES technique. The hybrid technique serves as a temporary approach to aid in developing the NOTES technique. A rectal or vaginal port of entry enables and facilitates gastrointestinal NOTES by using available laparoscopic instruments. The common operations performed today in the laparoscopic fashion could be probably performed in the NOTES approach. The safety of these procedures, however, is yet to be determined.
Pereira, Keith; Salsamendi, Jason; Fan, Ji
2015-10-01
Recipients of liver transplant are surviving longer as both the surgical procedure and postsurgical care have improved. Despite improvements, serious complications from the procedure remain that significantly affect patient outcome and may result in retransplant. Refractory ascites is one complication, occurring in about 5.6% of transplant recipients. Management of refractory ascites after liver transplant presents a challenge to the multidisciplinary team caring for these patients. We discuss approaches to the diagnosis and treatment of refractory ascites after liver transplant, based on a literature review, with a primary focus on vascular causes. These approaches are illustrated by case examples highlighting our experiences at an academic tertiary medical center. We propose a clinical practice algorithm for optimal endovascular treatment of refractory ascites after liver transplant. The cornerstone of refractory ascites care is diagnosis and treatment of the cause. Vascular causes are not infrequently encountered and, if not treated early, are associated with graft loss and high morbidity and mortality and are major indications for retransplant. For patients with recurrent disease or graft rejection needing large volume paracentesis, the use of a transjugular intrahepatic portosystemic shunt may serve as a bridge to more definitive treatment (retransplant), although it may not be as effective for managing ascites as splenic artery embolization, arguably underused, which is emerging as a potential alternative treatment option. A multidisciplinary strategy for the diagnosis and care of patients with refractory ascites after liver transplant is crucial, with endovascular treatment playing an important role. The aim is for this document to serve as a concise and informative reference to be used by those who may care for patients with this rare yet serious diagnosis.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-17
... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 1 [GC Docket No. 10-44; DA 12-1401] Notice of... . SUPPLEMENTARY INFORMATION: This is a synopsis of the Commission's Public Notice, document DA 12-1401, released... Procedure of Serving Parties in an Electronic Format. The full text of DA [[Page 57036
5 CFR 1203.14 - Serving documents.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 5 Administrative Personnel 3 2014-01-01 2014-01-01 false Serving documents. 1203.14 Section 1203... REVIEW OF RULES AND REGULATIONS OF THE OFFICE OF PERSONNEL MANAGEMENT Procedures for Review § 1203.14 Serving documents. (a) Parties. In every case, the person requesting regulation review must serve a copy...
5 CFR 1203.14 - Serving documents.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 5 Administrative Personnel 3 2011-01-01 2011-01-01 false Serving documents. 1203.14 Section 1203... REVIEW OF RULES AND REGULATIONS OF THE OFFICE OF PERSONNEL MANAGEMENT Procedures for Review § 1203.14 Serving documents. (a) Parties. In every case, the person requesting regulation review must serve a copy...
5 CFR 1203.14 - Serving documents.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 5 Administrative Personnel 3 2012-01-01 2012-01-01 false Serving documents. 1203.14 Section 1203... REVIEW OF RULES AND REGULATIONS OF THE OFFICE OF PERSONNEL MANAGEMENT Procedures for Review § 1203.14 Serving documents. (a) Parties. In every case, the person requesting regulation review must serve a copy...
5 CFR 1203.14 - Serving documents.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 5 Administrative Personnel 3 2013-01-01 2013-01-01 false Serving documents. 1203.14 Section 1203... REVIEW OF RULES AND REGULATIONS OF THE OFFICE OF PERSONNEL MANAGEMENT Procedures for Review § 1203.14 Serving documents. (a) Parties. In every case, the person requesting regulation review must serve a copy...
5 CFR 1203.14 - Serving documents.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Serving documents. 1203.14 Section 1203... REVIEW OF RULES AND REGULATIONS OF THE OFFICE OF PERSONNEL MANAGEMENT Procedures for Review § 1203.14 Serving documents. (a) Parties. In every case, the person requesting regulation review must serve a copy...
Shinbane, Jerold S; Saxon, Leslie A
Advances in imaging technology have led to a paradigm shift from planning of cardiovascular procedures and surgeries requiring the actual patient in a "brick and mortar" hospital to utilization of the digitalized patient in the virtual hospital. Cardiovascular computed tomographic angiography (CCTA) and cardiovascular magnetic resonance (CMR) digitalized 3-D patient representation of individual patient anatomy and physiology serves as an avatar allowing for virtual delineation of the most optimal approaches to cardiovascular procedures and surgeries prior to actual hospitalization. Pre-hospitalization reconstruction and analysis of anatomy and pathophysiology previously only accessible during the actual procedure could potentially limit the intrinsic risks related to time in the operating room, cardiac procedural laboratory and overall hospital environment. Although applications are specific to areas of cardiovascular specialty focus, there are unifying themes related to the utilization of technologies. The virtual patient avatar computer can also be used for procedural planning, computational modeling of anatomy, simulation of predicted therapeutic result, printing of 3-D models, and augmentation of real time procedural performance. Examples of the above techniques are at various stages of development for application to the spectrum of cardiovascular disease processes, including percutaneous, surgical and hybrid minimally invasive interventions. A multidisciplinary approach within medicine and engineering is necessary for creation of robust algorithms for maximal utilization of the virtual patient avatar in the digital medical center. Utilization of the virtual advanced cardiac imaging patient avatar will play an important role in the virtual health care system. Although there has been a rapid proliferation of early data, advanced imaging applications require further assessment and validation of accuracy, reproducibility, standardization, safety, efficacy, quality, cost effectiveness, and overall value to medical care. Copyright © 2018 Society of Cardiovascular Computed Tomography. Published by Elsevier Inc. All rights reserved.
Impact of backwashing procedures on deep bed filtration productivity in drinking water treatment.
Slavik, Irene; Jehmlich, Alexander; Uhl, Wolfgang
2013-10-15
Backwash procedures for deep bed filters were evaluated and compared by means of a new integrated approach based on productivity. For this, different backwash procedures were experimentally evaluated by using a pilot plant for direct filtration. A standard backwash mode as applied in practice served as a reference and effluent turbidity was used as the criterion for filter run termination. The backwash water volumes needed, duration of the filter-to-waste period, time out of operation, total volume discharged and filter run-time were determined and used to calculate average filtration velocity and average productivity. Results for filter run-times, filter backwash volumes, and filter-to-waste volumes showed considerable differences between the backwash procedures. Thus, backwash procedures with additional clear flushing phases were characterised by an increased need for backwash water. However, this additional water consumption could not be compensated by savings during filter ripening. Compared to the reference backwash procedure, filter run-times were longer for both single-media and dual-media filters when air scour and air/water flush were optimised with respect to flow rates and the proportion of air and water. This means that drinking water production time is longer and less water is needed for filter bed cleaning. Also, backwashing with additional clear flushing phases resulted in longer filter run-times before turbidity breakthrough. However, regarding the productivity of the filtration process, it was shown that it was almost the same for all of the backwash procedures investigated in this study. Due to this unexpected finding, the relationships between filter bed cleaning, filter ripening and filtration performance were considered and important conclusions and new approaches for process optimisation and resource savings were derived. Copyright © 2013 Elsevier Ltd. All rights reserved.
The use of observational diaries in in-training evaluation: student perceptions.
Govaerts, Marjan J B; van der Vleuten, Cees P M; Schuwirth, Lambert W T; Muijtjens, Arno M M
2005-08-01
In health science education clinical clerkships serve the twofold purpose of guiding student learning and assessment of performance. Evidently, both formative and summative assessment procedures are needed in clerkship assessment. In-training evaluation (ITE) has the potential to serve both assessment functions. Implementation of effective ITE, however, has been shown to be problematic, partly because integration of assessment functions may have negative consequences for teaching and learning. This study investigates student perceptions of the impact of an integrated assessment approach, seeking to refine criteria for effective ITE. In the curriculum of Maastricht Midwifery School (MMS), clerkship assessment is based on ITE serving both assessment functions. The ITE model is based on principles of extensive work sampling, and frequent documentation of performance. A focus group technique was used to explore student perceptions on the impact of the ITE approach on student learning and supervisor teaching behaviour, and on the usefulness of information for decision making. Results indicate that the assessment approach is effective in guidance of student learning. Furthermore, students consider the frequent performance documentation essential in clerkship grading. Acceptance and effectivity of ITE requires a learning environment which is safe and respectful. Transparency of assessment processes is the key to success. Suggestions for improvement focus on variation in evaluation formats, improvement of feedback (narrative, complete) and student involvement in assessment. ITE can fulfill both its formative and summative purposes when some crucial conditions are taken into account. Careful training of both supervisors and students in the use of ITE for student learning and performance measurement is essential.
The four faces of mass customization.
Gilmore, J H; Pine, B J
1997-01-01
Virtually all executives today recognize the need to provide outstanding service to customers. Focusing on the customer, however, is both an imperative and a potential curse. In their desire to become customer driven, many companies have resorted to inventing new programs and procedures to meet every customer's request. But as customers and their needs grow increasingly diverse, such an approach has become a surefire way to add unnecessary cost and complexity to operations. Companies around the world have embraced mass customization in an attempt to avoid those pitfalls. Readily available information technology and flexible work processes permit them to customize goods or services for individual customers in high volumes at low cost. But many managers have discovered that mass customization itself can produce unnecessary cost and complexity. They are realizing that they did not examine thoroughly enough what kind of customization their customers would value before they plunged ahead. That is understandable. Until now, no framework has existed to help managers determine the type of customization they should pursue. James Gilmore and Joseph Pine provide managers with just such a framework. They have identified four distinct approaches to customization. When designing or redesigning a product, process, or business unit, managers should examine each approach for possible insights into how to serve their customers best. In some cases, a single approach will dominate the design. More often, however, managers will need a mix of some or all of the four approaches to serve their own particular set of customers.
Diffraction phase microscopy realized with an automatic digital pinhole
NASA Astrophysics Data System (ADS)
Zheng, Cheng; Zhou, Renjie; Kuang, Cuifang; Zhao, Guangyuan; Zhang, Zhimin; Liu, Xu
2017-12-01
We report a novel approach to diffraction phase microscopy (DPM) with automatic pinhole alignment. The pinhole, which serves as a spatial low-pass filter to generate a uniform reference beam, is made out of a liquid crystal display (LCD) device that allows for electrical control. We have made DPM more accessible to users, while maintaining high phase measurement sensitivity and accuracy, through exploring low cost optical components and replacing the tedious pinhole alignment process with an automatic pinhole optical alignment procedure. Due to its flexibility in modifying the size and shape, this LCD device serves as a universal filter, requiring no future replacement. Moreover, a graphic user interface for real-time phase imaging has been also developed by using a USB CMOS camera. Experimental results of height maps of beads sample and live red blood cells (RBCs) dynamics are also presented, making this system ready for broad adaption to biological imaging and material metrology.
NHANES Monitoring of Serum 25-Hydroxyvitamin D: A Roundtable Summary123
Yetley, Elizabeth A.; Pfeiffer, Christine M.; Schleicher, Rosemary L.; Phinney, Karen W.; Lacher, David A.; Christakos, Sylvia; Eckfeldt, John H.; Fleet, James C.; Howard, George; Hoofnagle, Andrew N.; Hui, Siu L.; Lensmeyer, Gary L.; Massaro, Joseph; Peacock, Munro; Rosner, Bernard; Wiebe, Donald; Bailey, Regan L.; Coates, Paul M.; Looker, Anne C.; Sempos, Christopher; Johnson, Clifford L.; Picciano, Mary Frances
2010-01-01
A roundtable to discuss monitoring of serum 25-hydroxyvitamin D [25(OH)D] in the NHANES was held in late July 2009. Topics included the following: 1) options for dealing with assay fluctuations in serum 25(OH)D in the NHANES conducted between 1988 and 2006; 2) approaches for transitioning between the RIA used in the NHANES between 1988 and 2006 to the liquid chromatography tandem MS (LC-MS/MS) measurement procedure to be used in NHANES 2007 and later; 3) approaches for integrating the recently available standard reference material for vitamin D in human serum (SRM 972) from the National Institute of Standards and Technology (NIST) into the NHANES; 4) questions regarding whether the C-3 epimer of 25-hydroxyvitamin D3 [3-epi-25(OH)D3] should be measured in NHANES 2007 and later; and 5) identification of research and educational needs. The roundtable experts agreed that the NHANES data needed to be adjusted to control for assay fluctuations and offered several options for addressing this issue. The experts suggested that the LC-MS/MS measurement procedure developed by NIST could serve as a higher order reference measurement procedure. They noted the need for a commutability study for the recently released NIST SRM 972 across a range of measurement procedures. They suggested that federal agencies and professional organizations work with manufacturers to improve the quality and comparability of measurement procedures across all laboratories. The experts noted the preliminary nature of the evidence of the 3-epi-25(OH)D3 but felt that it should be measured in 2007 NHANES and later. PMID:20881084
Nguyen, Nam-Ninh; Srihari, Sriganesh; Leong, Hon Wai; Chong, Ket-Fah
2015-10-01
Determining the entire complement of enzymes and their enzymatic functions is a fundamental step for reconstructing the metabolic network of cells. High quality enzyme annotation helps in enhancing metabolic networks reconstructed from the genome, especially by reducing gaps and increasing the enzyme coverage. Currently, structure-based and network-based approaches can only cover a limited number of enzyme families, and the accuracy of homology-based approaches can be further improved. Bottom-up homology-based approach improves the coverage by rebuilding Hidden Markov Model (HMM) profiles for all known enzymes. However, its clustering procedure relies firmly on BLAST similarity score, ignoring protein domains/patterns, and is sensitive to changes in cut-off thresholds. Here, we use functional domain architecture to score the association between domain families and enzyme families (Domain-Enzyme Association Scoring, DEAS). The DEAS score is used to calculate the similarity between proteins, which is then used in clustering procedure, instead of using sequence similarity score. We improve the enzyme annotation protocol using a stringent classification procedure, and by choosing optimal threshold settings and checking for active sites. Our analysis shows that our stringent protocol EnzDP can cover up to 90% of enzyme families available in Swiss-Prot. It achieves a high accuracy of 94.5% based on five-fold cross-validation. EnzDP outperforms existing methods across several testing scenarios. Thus, EnzDP serves as a reliable automated tool for enzyme annotation and metabolic network reconstruction. Available at: www.comp.nus.edu.sg/~nguyennn/EnzDP .
This procedure summarizes the sample shipping procedures that have been described in the individual NHEXAS sample collection protocols. This procedure serves as a quick reference tool for the field staff when samples are prepared for shipment at the field lab/staging area. For ea...
Interpretation of Do Not Attempt Resuscitation Orders for Children Requiring Anesthesia and Surgery.
Fallat, Mary E; Hardy, Courtney
2018-05-01
This clinical report addresses the topic of pre-existing do not attempt resuscitation or limited resuscitation orders for children and adolescents undergoing anesthesia and surgery. Pertinent considerations for the clinician include the rights of children, decision-making by parents or legally approved representatives, the process of informed consent, and the roles of surgeon and anesthesiologist. A process of re-evaluation of the do not attempt resuscitation orders, called "required reconsideration," should be incorporated into the process of informed consent for surgery and anesthesia, distinguishing between goal-directed and procedure-directed approaches. The child's individual needs are best served by allowing the parent or legally approved representative and involved clinicians to consider whether full resuscitation, limitations based on procedures, or limitations based on goals is most appropriate. Copyright © 2018 by the American Academy of Pediatrics.
Determining procedures for simulation-based training in radiology: a nationwide needs assessment.
Nayahangan, Leizl Joy; Nielsen, Kristina Rue; Albrecht-Beste, Elisabeth; Bachmann Nielsen, Michael; Paltved, Charlotte; Lindorff-Larsen, Karen Gilboe; Nielsen, Bjørn Ulrik; Konge, Lars
2018-06-01
New training modalities such as simulation are widely accepted in radiology; however, development of effective simulation-based training programs is challenging. They are often unstructured and based on convenience or coincidence. The study objective was to perform a nationwide needs assessment to identify and prioritize technical procedures that should be included in a simulation-based curriculum. A needs assessment using the Delphi method was completed among 91 key leaders in radiology. Round 1 identified technical procedures that radiologists should learn. Round 2 explored frequency of procedure, number of radiologists performing the procedure, risk and/or discomfort for patients, and feasibility for simulation. Round 3 was elimination and prioritization of procedures. Response rates were 67 %, 70 % and 66 %, respectively. In Round 1, 22 technical procedures were included. Round 2 resulted in pre-prioritization of procedures. In round 3, 13 procedures were included in the final prioritized list. The three highly prioritized procedures were ultrasound-guided (US) histological biopsy and fine-needle aspiration, US-guided needle puncture and catheter drainage, and basic abdominal ultrasound. A needs assessment identified and prioritized 13 technical procedures to include in a simulation-based curriculum. The list may be used as guide for development of training programs. • Simulation-based training can supplement training on patients in radiology. • Development of simulation-based training should follow a structured approach. • The CAMES Needs Assessment Formula explores needs for simulation training. • A national Delphi study identified and prioritized procedures suitable for simulation training. • The prioritized list serves as guide for development of courses in radiology.
Deib, Gerard; Johnson, Alex; Unberath, Mathias; Yu, Kevin; Andress, Sebastian; Qian, Long; Osgood, Gregory; Navab, Nassir; Hui, Ferdinand; Gailloud, Philippe
2018-05-30
Optical see-through head mounted displays (OST-HMDs) offer a mixed reality (MixR) experience with unhindered procedural site visualization during procedures using high resolution radiographic imaging. This technical note describes our preliminary experience with percutaneous spine procedures utilizing OST-HMD as an alternative to traditional angiography suite monitors. MixR visualization was achieved using the Microsoft HoloLens system. Various spine procedures (vertebroplasty, kyphoplasty, and percutaneous discectomy) were performed on a lumbar spine phantom with commercially available devices. The HMD created a real time MixR environment by superimposing virtual posteroanterior and lateral views onto the interventionalist's field of view. The procedures were filmed from the operator's perspective. Videos were reviewed to assess whether key anatomic landmarks and materials were reliably visualized. Dosimetry and procedural times were recorded. The operator completed a questionnaire following each procedure, detailing benefits, limitations, and visualization mode preferences. Percutaneous vertebroplasty, kyphoplasty, and discectomy procedures were successfully performed using OST-HMD image guidance on a lumbar spine phantom. Dosimetry and procedural time compared favorably with typical procedural times. Conventional and MixR visualization modes were equally effective in providing image guidance, with key anatomic landmarks and materials reliably visualized. This preliminary study demonstrates the feasibility of utilizing OST-HMDs for image guidance in interventional spine procedures. This novel visualization approach may serve as a valuable adjunct tool during minimally invasive percutaneous spine treatment. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
77 FR 23208 - Assessment of Mediation and Arbitration Procedures
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-18
... No. EP 699] Assessment of Mediation and Arbitration Procedures AGENCY: Surface Transportation Board... Mediation and Arbitration Procedures, EP 699 (STB served Mar. 28, 2012),\\1\\ the Surface Transportation Board... favors the resolution of disputes through the use of mediation and arbitration procedures, in lieu of...
A Functional Analytic Approach To Computer-Interactive Mathematics
2005-01-01
Following a pretest, 11 participants who were naive with regard to various algebraic and trigonometric transformations received an introductory lecture regarding the fundamentals of the rectangular coordinate system. Following the lecture, they took part in a computer-interactive matching-to-sample procedure in which they received training on particular formula-to-formula and formula-to-graph relations as these formulas pertain to reflections and vertical and horizontal shifts. In training A-B, standard formulas served as samples and factored formulas served as comparisons. In training B-C, factored formulas served as samples and graphs served as comparisons. Subsequently, the program assessed for mutually entailed B-A and C-B relations as well as combinatorially entailed C-A and A-C relations. After all participants demonstrated mutual entailment and combinatorial entailment, we employed a test of novel relations to assess 40 different and complex variations of the original training formulas and their respective graphs. Six of 10 participants who completed training demonstrated perfect or near-perfect performance in identifying novel formula-to-graph relations. Three of the 4 participants who made more than three incorrect responses during the assessment of novel relations showed some commonality among their error patterns. Derived transfer of stimulus control using mathematical relations is discussed. PMID:15898471
A functional analytic approach to computer-interactive mathematics.
Ninness, Chris; Rumph, Robin; McCuller, Glen; Harrison, Carol; Ford, Angela M; Ninness, Sharon K
2005-01-01
Following a pretest, 11 participants who were naive with regard to various algebraic and trigonometric transformations received an introductory lecture regarding the fundamentals of the rectangular coordinate system. Following the lecture, they took part in a computer-interactive matching-to-sample procedure in which they received training on particular formula-to-formula and formula-to-graph relations as these formulas pertain to reflections and vertical and horizontal shifts. In training A-B, standard formulas served as samples and factored formulas served as comparisons. In training B-C, factored formulas served as samples and graphs served as comparisons. Subsequently, the program assessed for mutually entailed B-A and C-B relations as well as combinatorially entailed C-A and A-C relations. After all participants demonstrated mutual entailment and combinatorial entailment, we employed a test of novel relations to assess 40 different and complex variations of the original training formulas and their respective graphs. Six of 10 participants who completed training demonstrated perfect or near-perfect performance in identifying novel formula-to-graph relations. Three of the 4 participants who made more than three incorrect responses during the assessment of novel relations showed some commonality among their error patterns. Derived transfer of stimulus control using mathematical relations is discussed.
ERIC Educational Resources Information Center
Frasier, James E.; Stanton, William
This publication reports the development of the vocational-technical resource consortia in Ohio and identifies the operational procedures associated with successful programs. Five exemplary consortia were studied in some depth; however, data were obtained from all of the 23 consortia in the state. The research indicates that the consortium is an…
[Family medicine and functional somatic syndromes].
Nago, Naoki
2009-09-01
Between psychosomatic medicine and psychiatry, FSS (functional somatic syndromes) patients are often visiting a family doctor. For FSS, the role of family physicians is large, but the family physicians are not required for the role of diagnosis and treatment of FSS. Rather, appropriate referral to a specialist to exclude organic disease is important and a role as the coordinator is large to the patient to refuse a psychiatric consultation. To serve as a role for such coordination, a family physician has to response the patient's emotional side and focus on the construction of the doctor-patient relationship and response. I also think of structuralism medicine approach to describe disease from the meta-level as a new procedure to the patient. This approach consists of 4 components, 'entity', 'phenomenon', 'words', and 'I'. This may be a useful approach to family physicians who coordinate the overall for FSS patients' management.
Pharmacology Goes Concept-Based: Course Design, Implementation, and Evaluation.
Lanz, Amelia; Davis, Rebecca G
Although concept-based curricula are frequently discussed in the nursing education literature, little information exists to guide the development of a concept-based pharmacology course. Traditionally, nursing pharmacology courses are taught with an emphasis on drug class where a prototype drug serves as an exemplar. When transitioning pharmacology to a concept-based course, special considerations are in order. How can educators successfully integrate essential pharmacological content into a curriculum structured around nursing concepts? This article presents one approach to the design and implementation of a concept-based undergraduate pharmacology course. Planning methods, supportive teaching strategies, and course evaluation procedures are discussed.
NASA Astrophysics Data System (ADS)
Mulsow, C.
2012-07-01
The paper describes the determination of the percentage area of bitumen on partly covered aggregate. This task is a typical issue in material testing in road construction. The asphalt components bitumen and aggregate are subjected to defined mechanical stress in the presence of water in order to test the affine properties of the components. The degree to which the bitumen separates from the aggregate surface serves as an indicator for the quality of the affinity. Until now, examiners have been judging the coverage degree of samples by visual rating. Several research projects attempted to replace the error-prone subjective assessment by automatic procedures. These procedures analyse the different chromaticities of aggregate and bitumen in RGB images. However, these approaches as a whole are not reliable enough because of the rather specific requirements that are made on the environmental conditions when the picture is taken (illumination, exclusion of extraneous light) and also on the lab assistant (manual definition of training areas, management of camera and illumination parameters). Moreover, the analysis is not suitable for all types of rock because of the necessary difference in colour between bitumen and aggregate (e.g. dark rock samples). Contrary to previous approaches, the new multi-directional reflectance measurements use the different surface characteristics of bitumen and aggregate instead of the chromaticities as separation criteria. These differences are made visible by directional lighting with a laser. The diffuse reflection from the aggregate surface and the directional reflection from the optically smoother bitumen produce definitely distinguishable brightnesses in the image. Thus the colour of the material is of no significance. The approach was used in a procedure and assessed. The paper presents the method itself, approaches for the elimination of reflections and first results. Moreover, the measuring principle is compared with existing procedures and benefits and drawbacks are outlined.
Condition Number Regularized Covariance Estimation*
Won, Joong-Ho; Lim, Johan; Kim, Seung-Jean; Rajaratnam, Bala
2012-01-01
Estimation of high-dimensional covariance matrices is known to be a difficult problem, has many applications, and is of current interest to the larger statistics community. In many applications including so-called the “large p small n” setting, the estimate of the covariance matrix is required to be not only invertible, but also well-conditioned. Although many regularization schemes attempt to do this, none of them address the ill-conditioning problem directly. In this paper, we propose a maximum likelihood approach, with the direct goal of obtaining a well-conditioned estimator. No sparsity assumption on either the covariance matrix or its inverse are are imposed, thus making our procedure more widely applicable. We demonstrate that the proposed regularization scheme is computationally efficient, yields a type of Steinian shrinkage estimator, and has a natural Bayesian interpretation. We investigate the theoretical properties of the regularized covariance estimator comprehensively, including its regularization path, and proceed to develop an approach that adaptively determines the level of regularization that is required. Finally, we demonstrate the performance of the regularized estimator in decision-theoretic comparisons and in the financial portfolio optimization setting. The proposed approach has desirable properties, and can serve as a competitive procedure, especially when the sample size is small and when a well-conditioned estimator is required. PMID:23730197
Condition Number Regularized Covariance Estimation.
Won, Joong-Ho; Lim, Johan; Kim, Seung-Jean; Rajaratnam, Bala
2013-06-01
Estimation of high-dimensional covariance matrices is known to be a difficult problem, has many applications, and is of current interest to the larger statistics community. In many applications including so-called the "large p small n " setting, the estimate of the covariance matrix is required to be not only invertible, but also well-conditioned. Although many regularization schemes attempt to do this, none of them address the ill-conditioning problem directly. In this paper, we propose a maximum likelihood approach, with the direct goal of obtaining a well-conditioned estimator. No sparsity assumption on either the covariance matrix or its inverse are are imposed, thus making our procedure more widely applicable. We demonstrate that the proposed regularization scheme is computationally efficient, yields a type of Steinian shrinkage estimator, and has a natural Bayesian interpretation. We investigate the theoretical properties of the regularized covariance estimator comprehensively, including its regularization path, and proceed to develop an approach that adaptively determines the level of regularization that is required. Finally, we demonstrate the performance of the regularized estimator in decision-theoretic comparisons and in the financial portfolio optimization setting. The proposed approach has desirable properties, and can serve as a competitive procedure, especially when the sample size is small and when a well-conditioned estimator is required.
7 CFR 1794.41 - Document requirements.
Code of Federal Regulations, 2010 CFR
2010-01-01
... addresses all applicable environmental issues, the ER will normally serve as RUS' EA. However, RUS reserves... AGRICULTURE (CONTINUED) ENVIRONMENTAL POLICIES AND PROCEDURES Procedure for Environmental Assessments § 1794...
32 CFR 105.10 - SARC and SAPR VA procedures.
Code of Federal Regulations, 2014 CFR
2014-07-01
... CIVILIAN SEXUAL ASSAULT PREVENTION AND RESPONSE PROGRAM PROCEDURES § 105.10 SARC and SAPR VA procedures. (a) SARC procedures. The SARC shall: (1) Serve as the single point of contact to coordinate sexual assault response when a sexual assault is reported. All SARCs shall be authorized to perform VA duties in...
32 CFR 105.10 - SARC and SAPR VA procedures.
Code of Federal Regulations, 2013 CFR
2013-07-01
... CIVILIAN SEXUAL ASSAULT PREVENTION AND RESPONSE PROGRAM PROCEDURES § 105.10 SARC and SAPR VA procedures. (a) SARC procedures. The SARC shall: (1) Serve as the single point of contact to coordinate sexual assault response when a sexual assault is reported. All SARCs shall be authorized to perform VA duties in...
49 CFR 1503.421 - Streamlined civil penalty procedures for certain security violations.
Code of Federal Regulations, 2010 CFR
2010-10-01
... PROCEDURAL RULES INVESTIGATIVE AND ENFORCEMENT PROCEDURES Assessment of Civil Penalties by TSA § 1503.421 Streamlined civil penalty procedures for certain security violations. (a) Notice of violation. TSA, at the... violations described in the section and as otherwise provided by the Administrator. TSA may serve a Notice of...
14 CFR 1263.108 - Procedure in the event of an adverse ruling.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Procedure in the event of an adverse ruling. 1263.108 Section 1263.108 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION DEMAND FOR INFORMATION OR TESTIMONY SERVED ON AGENCY EMPLOYEES; PROCEDURES § 1263.108 Procedure in the event...
14 CFR 1263.108 - Procedure in the event of an adverse ruling.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Procedure in the event of an adverse ruling. 1263.108 Section 1263.108 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION DEMAND FOR INFORMATION OR TESTIMONY SERVED ON AGENCY EMPLOYEES; PROCEDURES § 1263.108 Procedure in the event...
14 CFR 1263.108 - Procedure in the event of an adverse ruling.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Procedure in the event of an adverse ruling. 1263.108 Section 1263.108 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION DEMAND FOR INFORMATION OR TESTIMONY SERVED ON AGENCY EMPLOYEES; PROCEDURES § 1263.108 Procedure in the event...
14 CFR 1263.108 - Procedure in the event of an adverse ruling.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Procedure in the event of an adverse ruling. 1263.108 Section 1263.108 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION DEMAND FOR INFORMATION OR TESTIMONY SERVED ON AGENCY EMPLOYEES; PROCEDURES § 1263.108 Procedure in the event...
77 FR 7237 - Railroad Cost Recovery Procedures-Productivity Adjustment
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-10
... Cost Recovery Procedures--Productivity Adjustment AGENCY: Surface Transportation Board. ACTION: Proposed railroad cost recovery procedures productivity adjustment. SUMMARY: In a decision served on... productivity for the 2006-2010 (5-year) averaging period. This represents a 0.6% decrease over the average for...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Goke, Sarah Hayes; Elliott, Nathan Ryan
The Sandia National Laboratories’ Internal Dosimetry Technical Basis Manual is intended to provide extended technical discussion and justification of the internal dosimetry program at SNL. It serves to record the approach to evaluating internal doses from radiobioassay data, and where appropriate, from workplace monitoring data per the Department of Energy Internal Dosimetry Program Guide DOE G 441.1C. The discussion contained herein is directed primarily to current and future SNL internal dosimetrists. In an effort to conserve space in the TBM and avoid duplication, it contains numerous references providing an entry point into the internal dosimetry literature relevant to this program.more » The TBM is not intended to act as a policy or procedure statement, but will supplement the information normally found in procedures or policy documents. The internal dosimetry program outlined in this manual is intended to meet the requirements of Federal Rule 10CFR835 for monitoring the workplace and for assessing internal radiation doses to workers.« less
Allanson, Paul; Petrie, Dennis
2013-01-01
The usual starting point for understanding changes in income-related health inequality (IRHI) over time has been regression-based decomposition procedures for the health concentration index. However the reliance on repeated cross-sectional analysis for this purpose prevents both the appropriate specification of the health function as a dynamic model and the identification of important determinants of the transition processes underlying IRHI changes such as those relating to mortality. This paper overcomes these limitations by developing alternative longitudinal procedures to analyse the role of health determinants in driving changes in IRHI through both morbidity changes and mortality, with our dynamic modelling framework also serving to identify their contribution to long-run or structural IRHI. The approach is illustrated by an empirical analysis of the causes of the increase in IRHI in Great Britain between 1999 and 2004. PMID:24036199
78 FR 10262 - Railroad Cost Recovery Procedures-Productivity Adjustment
Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-13
... Cost Recovery Procedures--Productivity Adjustment AGENCY: Surface Transportation Board, DOT. ACTION: Proposed railroad cost recovery procedures productivity adjustment. SUMMARY: In a decision served on... productivity for the 2007-2011 (5-year) averaging period. This represents a 0.1% increase over the average for...
75 FR 5170 - Railroad Cost Recovery Procedures-Productivity Adjustment
Federal Register 2010, 2011, 2012, 2013, 2014
2010-02-01
...)] Railroad Cost Recovery Procedures--Productivity Adjustment AGENCY: Surface Transportation Board, DOT. ACTION: Proposed Railroad Cost Recovery Procedures Productivity Adjustment. SUMMARY: In a decision served... railroad productivity for the 2004-2008 (5-year) averaging period. This is a decline of 0.5 of a percentage...
43 CFR 4.801 - Suspension of rules.
Code of Federal Regulations, 2011 CFR
2011-10-01
... Special Procedural Rules Applicable to Practice and Procedure for Hearings, Decisions, and Administrative... determination that no party will be unduly prejudiced and the ends of justice will thereby be served. ...
43 CFR 4.801 - Suspension of rules.
Code of Federal Regulations, 2014 CFR
2014-10-01
... Special Procedural Rules Applicable to Practice and Procedure for Hearings, Decisions, and Administrative... determination that no party will be unduly prejudiced and the ends of justice will thereby be served. ...
43 CFR 4.801 - Suspension of rules.
Code of Federal Regulations, 2013 CFR
2013-10-01
... Special Procedural Rules Applicable to Practice and Procedure for Hearings, Decisions, and Administrative... determination that no party will be unduly prejudiced and the ends of justice will thereby be served. ...
43 CFR 4.801 - Suspension of rules.
Code of Federal Regulations, 2012 CFR
2012-10-01
... Special Procedural Rules Applicable to Practice and Procedure for Hearings, Decisions, and Administrative... determination that no party will be unduly prejudiced and the ends of justice will thereby be served. ...
Multifactor Screener in OPEN: Scoring Procedures & Results
Scoring procedures were developed to convert a respondent's screener responses to estimates of individual dietary intake for percentage energy from fat, grams of fiber, and servings of fruits and vegetables.
Modeling of Stone-impact Resistance of Monolithic Glass Ply Using Continuum Damage Mechanics
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sun, Xin; Khaleel, Mohammad A.; Davies, Richard W.
2005-04-01
We study the stone-impact resistance of a monolithic glass ply using a combined experimental and computational approach. Instrumented stone impact tests were first carried out in controlled environment. Explicit finite element analyses were then used to simulate the interactions of the indentor and the glass layer during the impact event, and a continuum damage mechanics (CDM) model was used to describe the constitutive behavior of glass. The experimentally measured strain histories for low velocity impact served as validation of the modeling procedures. Next, stair-stepping impact experiments were performed with two indentor sizes on two glass ply thickness, and the testmore » results were used to calibrate the critical stress parameters used in the CDM constitutive model. The purpose of this study is to establish the modeling procedures and the CDM critical stress parameters under impact loading conditions. The modeling procedures and the CDM model will be used in our future studies to predict through-thickness damage evolution patterns for different laminated windshield designs in automotive applications.« less
15 CFR 904.244 - Production of documents and inspection.
Code of Federal Regulations, 2011 CFR
2011-01-01
... (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS CIVIL PROCEDURES Hearing and Appeal Procedures Discovery § 904.244 Production of documents and inspection. (a... the request is served. (b) Procedure. The request must set forth: (1) The items to be produced or...
15 CFR 904.244 - Production of documents and inspection.
Code of Federal Regulations, 2010 CFR
2010-01-01
... (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS CIVIL PROCEDURES Hearing and Appeal Procedures Discovery § 904.244 Production of documents and inspection. (a... the request is served. (b) Procedure. The request must set forth: (1) The items to be produced or...
75 FR 16575 - Railroad Cost Recovery Procedures-Productivity Adjustment
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-01
...)] Railroad Cost Recovery Procedures--Productivity Adjustment AGENCY: Surface Transportation Board. ACTION: Adoption of a railroad cost recovery procedures productivity adjustment. SUMMARY: By decision served on February 1, 2010, the Board proposed to adopt 1.010 (1.0% per year) as the 2008 productivity adjustment, as...
25 CFR 700.313 - Evidence and procedure.
Code of Federal Regulations, 2011 CFR
2011-04-01
... relevant evidence; (4) Take depositions or have depositions taken when the ends of justice would be served... conferences for the settlement or simplification of the issues; (7) Dispose of procedural requests or similar...
25 CFR 700.313 - Evidence and procedure.
Code of Federal Regulations, 2012 CFR
2012-04-01
... relevant evidence; (4) Take depositions or have depositions taken when the ends of justice would be served... conferences for the settlement or simplification of the issues; (7) Dispose of procedural requests or similar...
25 CFR 700.313 - Evidence and procedure.
Code of Federal Regulations, 2010 CFR
2010-04-01
... relevant evidence; (4) Take depositions or have depositions taken when the ends of justice would be served... conferences for the settlement or simplification of the issues; (7) Dispose of procedural requests or similar...
25 CFR 700.313 - Evidence and procedure.
Code of Federal Regulations, 2013 CFR
2013-04-01
... relevant evidence; (4) Take depositions or have depositions taken when the ends of justice would be served... conferences for the settlement or simplification of the issues; (7) Dispose of procedural requests or similar...
Kołodziej, Łukasz; Bohatyrewicz, Andrzej; Kedzierski, Michał; Kotrych, Daniel
2008-01-01
The authors reviewed their results of tibiotalocalcaneal arthrodesis by retrograde intramedullary nail as a salvage procedure in treatment of the most severe squeal of talar, calcanear, ankle and pilon fractures in twelve patients. Their average age was 55 years. The average follow up ranged from 8 to 25 months. Patients were assessed by AOFAS hindfoot scale and patient satisfaction. The arthrodesis was performed via lateral, transfibular approach. Solid fusion was achieved in all but one patient. In four patients final foot position was not an optimal one for hindfoot arthrodesis. 15 months after surgery a below knee amputation was performed in one patient because of limb ischemia due to posttraumatic lesion of booth tibialis anterior and posterior arteries. Nail construct allows to perform an intrafragmentry compression between bone ends what enhances bone healing and fusion but in some cases nail introducing must be accompanied by osteotomies or pseudoarthrosis resection. The transfibular, lateral approach is extremely useful in exploration of talocalcaneal ant talocrulaljoints. Resection of lateral malleolus reduces soft tissue tension and serve as a source of bone grafts, necessary in many reconstructive procedure.
Bolin, B. Levi; Singleton, Destiny L.; Akins, Chana K.
2014-01-01
Pavlovian drug discrimination (DD) procedures demonstrate that interoceptive drug stimuli may come to control behavior by informing the status of conditional relationships between stimuli and outcomes. This technique may provide insight into processes that contribute to drug-seeking, relapse, and other maladaptive behaviors associated with drug abuse. The purpose of the current research was to establish a model of Pavlovian DD in male Japanese quail. A Pavlovian conditioning procedure was used such that 3.0 mg/kg methamphetamine served as a feature positive stimulus for brief periods of visual access to a female quail and approach behavior was measured. After acquisition training, generalization tests were conducted with cocaine, nicotine, and haloperidol under extinction conditions. SCH 23390 was used to investigate the involvement of the dopamine D1 receptor subtype in the methamphetamine discriminative stimulus. Results showed that cocaine fully substituted for methamphetamine but nicotine only partially substituted for methamphetamine in quail. Haloperidol dose-dependently decreased approach behavior. Pretreatment with SCH 23390 modestly attenuated the methamphetamine discrimination suggesting that the D1 receptor subtype may be involved in the discriminative stimulus effects of methamphetamine. The findings are discussed in relation to drug abuse and associated negative health consequences. PMID:24965811
Unpredictable drug shortages: an ethical framework for short-term rationing in hospitals.
Rosoff, Philip M
2012-01-01
Periodic and unexpected shortages of drugs, biologics, and even medical devices have become commonplace in the United States. When shortages occur, hospitals and clinics need to decide how to ration their available stock. When such situations arise, institutions can choose from several different allocation schemes, such as first-come, first-served, a lottery, or a more rational and calculated approach. While the first two approaches sound reasonable at first glance, there are a number of problems associated with them, including the inability to make fine, individual patient-centered decisions. They also do not discriminate between what kinds of patients and what types of uses may be more deserving or reasonable than others. In this article I outline an ethically acceptable procedure for rationing drugs during a shortage in which demand outstrips supply.
Krishnaraj, R Navanietha; Chandran, Saravanan; Pal, Parimal; Berchmans, Sheela
2013-12-01
There is an immense interest among the researchers to identify new herbicides which are effective against the herbs without affecting the environment. In this work, photosynthetic pigments are used as the ligands to predict their herbicidal activity. The enzyme 5-enolpyruvylshikimate-3-phosphate (EPSP) synthase is a good target for the herbicides. Homology modeling of the target enzyme is done using Modeler 9.11 and the model is validated. Docking studies were performed with AutoDock Vina algorithm to predict the binding of the natural pigments such as β-carotene, chlorophyll a, chlorophyll b, phycoerythrin and phycocyanin to the target. β-carotene, phycoerythrin and phycocyanin have higher binding energies indicating the herbicidal activity of the pigments. This work reports a procedure to screen herbicides with computational molecular approach. These pigments will serve as potential bioherbicides in the future.
Analysis of longitudinal "time series" data in toxicology.
Cox, C; Cory-Slechta, D A
1987-02-01
Studies focusing on chronic toxicity or on the time course of toxicant effect often involve repeated measurements or longitudinal observations of endpoints of interest. Experimental design considerations frequently necessitate between-group comparisons of the resulting trends. Typically, procedures such as the repeated-measures analysis of variance have been used for statistical analysis, even though the required assumptions may not be satisfied in some circumstances. This paper describes an alternative analytical approach which summarizes curvilinear trends by fitting cubic orthogonal polynomials to individual profiles of effect. The resulting regression coefficients serve as quantitative descriptors which can be subjected to group significance testing. Randomization tests based on medians are proposed to provide a comparison of treatment and control groups. Examples from the behavioral toxicology literature are considered, and the results are compared to more traditional approaches, such as repeated-measures analysis of variance.
Large Animal Models of an In Vivo Bioreactor for Engineering Vascularized Bone.
Akar, Banu; Tatara, Alexander M; Sutradhar, Alok; Hsiao, Hui-Yi; Miller, Michael; Cheng, Ming-Huei; Mikos, Antonios G; Brey, Eric M
2018-04-12
Reconstruction of large skeletal defects is challenging due to the requirement for large volumes of donor tissue and the often complex surgical procedures. Tissue engineering has the potential to serve as a new source of tissue for bone reconstruction, but current techniques are often limited in regards to the size and complexity of tissue that can be formed. Building tissue using an in vivo bioreactor approach may enable the production of appropriate amounts of specialized tissue, while reducing issues of donor site morbidity and infection. Large animals are required to screen and optimize new strategies for growing clinically appropriate volumes of tissues in vivo. In this article, we review both ovine and porcine models that serve as models of the technique proposed for clinical engineering of bone tissue in vivo. Recent findings are discussed with these systems, as well as description of next steps required for using these models, to develop clinically applicable tissue engineering applications.
Cognition and procedure representational requirements for predictive human performance models
NASA Technical Reports Server (NTRS)
Corker, K.
1992-01-01
Models and modeling environments for human performance are becoming significant contributors to early system design and analysis procedures. Issues of levels of automation, physical environment, informational environment, and manning requirements are being addressed by such man/machine analysis systems. The research reported here investigates the close interaction between models of human cognition and models that described procedural performance. We describe a methodology for the decomposition of aircrew procedures that supports interaction with models of cognition on the basis of procedures observed; that serves to identify cockpit/avionics information sources and crew information requirements; and that provides the structure to support methods for function allocation among crew and aiding systems. Our approach is to develop an object-oriented, modular, executable software representation of the aircrew, the aircraft, and the procedures necessary to satisfy flight-phase goals. We then encode in a time-based language, taxonomies of the conceptual, relational, and procedural constraints among the cockpit avionics and control system and the aircrew. We have designed and implemented a goals/procedures hierarchic representation sufficient to describe procedural flow in the cockpit. We then execute the procedural representation in simulation software and calculate the values of the flight instruments, aircraft state variables and crew resources using the constraints available from the relationship taxonomies. The system provides a flexible, extensible, manipulative and executable representation of aircrew and procedures that is generally applicable to crew/procedure task-analysis. The representation supports developed methods of intent inference, and is extensible to include issues of information requirements and functional allocation. We are attempting to link the procedural representation to models of cognitive functions to establish several intent inference methods including procedural backtracking with concurrent search, temporal reasoning, and constraint checking for partial ordering of procedures. Finally, the representation is being linked to models of human decision making processes that include heuristic, propositional and prescriptive judgement models that are sensitive to the procedural content in which the valuative functions are being performed.
Using field inversion to quantify functional errors in turbulence closures
NASA Astrophysics Data System (ADS)
Singh, Anand Pratap; Duraisamy, Karthik
2016-04-01
A data-informed approach is presented with the objective of quantifying errors and uncertainties in the functional forms of turbulence closure models. The approach creates modeling information from higher-fidelity simulations and experimental data. Specifically, a Bayesian formalism is adopted to infer discrepancies in the source terms of transport equations. A key enabling idea is the transformation of the functional inversion procedure (which is inherently infinite-dimensional) into a finite-dimensional problem in which the distribution of the unknown function is estimated at discrete mesh locations in the computational domain. This allows for the use of an efficient adjoint-driven inversion procedure. The output of the inversion is a full-field of discrepancy that provides hitherto inaccessible modeling information. The utility of the approach is demonstrated by applying it to a number of problems including channel flow, shock-boundary layer interactions, and flows with curvature and separation. In all these cases, the posterior model correlates well with the data. Furthermore, it is shown that even if limited data (such as surface pressures) are used, the accuracy of the inferred solution is improved over the entire computational domain. The results suggest that, by directly addressing the connection between physical data and model discrepancies, the field inversion approach materially enhances the value of computational and experimental data for model improvement. The resulting information can be used by the modeler as a guiding tool to design more accurate model forms, or serve as input to machine learning algorithms to directly replace deficient modeling terms.
We performed the following steps with the NHIS 2005 Cancer Control Supplement dietary data to estimate the individual's intake of servings of fruits and vegetables, fiber, added sugar, calcium, and servings of dairy.
21 CFR 10.19 - Waiver, suspension, or modification of procedural requirements.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Waiver, suspension, or modification of procedural... modification of procedural requirements. The Commissioner or a presiding officer may, either voluntarily or at... hearing if no participant will be prejudiced, the ends of justice will thereby be served, and the action...
30 CFR 44.22 - Administrative law judges; powers and duties.
Code of Federal Regulations, 2014 CFR
2014-07-01
... ends of justice would be served; (5) To provide for discovery and determine its scope; (6) To regulate... procedural requests; (8) To hold conferences for settlement or simplification of issues by consent of the... record of the hearing. (d) Referral to Federal Rules of Civil Procedure and Evidence. On any procedural...
21 CFR 10.19 - Waiver, suspension, or modification of procedural requirements.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Waiver, suspension, or modification of procedural... modification of procedural requirements. The Commissioner or a presiding officer may, either voluntarily or at... hearing if no participant will be prejudiced, the ends of justice will thereby be served, and the action...
21 CFR 10.19 - Waiver, suspension, or modification of procedural requirements.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Waiver, suspension, or modification of procedural... modification of procedural requirements. The Commissioner or a presiding officer may, either voluntarily or at... hearing if no participant will be prejudiced, the ends of justice will thereby be served, and the action...
21 CFR 10.19 - Waiver, suspension, or modification of procedural requirements.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Waiver, suspension, or modification of procedural... modification of procedural requirements. The Commissioner or a presiding officer may, either voluntarily or at... hearing if no participant will be prejudiced, the ends of justice will thereby be served, and the action...
21 CFR 10.19 - Waiver, suspension, or modification of procedural requirements.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Waiver, suspension, or modification of procedural... modification of procedural requirements. The Commissioner or a presiding officer may, either voluntarily or at... hearing if no participant will be prejudiced, the ends of justice will thereby be served, and the action...
30 CFR 44.22 - Administrative law judges; powers and duties.
Code of Federal Regulations, 2012 CFR
2012-07-01
... ends of justice would be served; (5) To provide for discovery and determine its scope; (6) To regulate... procedural requests; (8) To hold conferences for settlement or simplification of issues by consent of the... record of the hearing. (d) Referral to Federal Rules of Civil Procedure and Evidence. On any procedural...
Data Input for Publishers. State-of-the-Art Report.
ERIC Educational Resources Information Center
Buckland, Lawrence F.
Intended to serve as a guide for selecting the most suitable automated method for preparing and sending papers for publication, this report briefly describes data entry and editing procedures available from one publisher (Inforonics) and provides an estimate of processing costs for each procedure. The procedures, arranged in order of increasing…
This procedure describes in detail the rules and regulations governing the proper use and maintenance of laboratory notebooks. The purpose of laboratory notebooks was to provide a permanent legal record of experimental procedures and results. Thus, the laboratory notebook served ...
Federal Assistance for Programs Serving the Handicapped. Third Edition.
ERIC Educational Resources Information Center
Office of Human Development (DHEW), Washington, DC. Office for Handicapped Individuals.
The guide presents information on more than 200 federally assisted programs serving the handicapped. Information on uses and restrictions, types of assistance, eligibility requirements; application procedures, appropriations, program accomplishments, enabling legislation, and contact persons are listed for programs receiving four types of…
Sliding to predict: vision-based beating heart motion estimation by modeling temporal interactions.
Aviles-Rivero, Angelica I; Alsaleh, Samar M; Casals, Alicia
2018-03-01
Technical advancements have been part of modern medical solutions as they promote better surgical alternatives that serve to the benefit of patients. Particularly with cardiovascular surgeries, robotic surgical systems enable surgeons to perform delicate procedures on a beating heart, avoiding the complications of cardiac arrest. This advantage comes with the price of having to deal with a dynamic target which presents technical challenges for the surgical system. In this work, we propose a solution for cardiac motion estimation. Our estimation approach uses a variational framework that guarantees preservation of the complex anatomy of the heart. An advantage of our approach is that it takes into account different disturbances, such as specular reflections and occlusion events. This is achieved by performing a preprocessing step that eliminates the specular highlights and a predicting step, based on a conditional restricted Boltzmann machine, that recovers missing information caused by partial occlusions. We carried out exhaustive experimentations on two datasets, one from a phantom and the other from an in vivo procedure. The results show that our visual approach reaches an average minima in the order of magnitude of [Formula: see text] while preserving the heart's anatomical structure and providing stable values for the Jacobian determinant ranging from 0.917 to 1.015. We also show that our specular elimination approach reaches an accuracy of 99% compared to a ground truth. In terms of prediction, our approach compared favorably against two well-known predictors, NARX and EKF, giving the lowest average RMSE of 0.071. Our approach avoids the risks of using mechanical stabilizers and can also be effective for acquiring the motion of organs other than the heart, such as the lung or other deformable objects.
Merging spatially variant physical process models under an optimized systems dynamics framework.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cain, William O.; Lowry, Thomas Stephen; Pierce, Suzanne A.
The complexity of water resource issues, its interconnectedness to other systems, and the involvement of competing stakeholders often overwhelm decision-makers and inhibit the creation of clear management strategies. While a range of modeling tools and procedures exist to address these problems, they tend to be case specific and generally emphasize either a quantitative and overly analytic approach or present a qualitative dialogue-based approach lacking the ability to fully explore consequences of different policy decisions. The integration of these two approaches is needed to drive toward final decisions and engender effective outcomes. Given these limitations, the Computer Assisted Dispute Resolution systemmore » (CADRe) was developed to aid in stakeholder inclusive resource planning. This modeling and negotiation system uniquely addresses resource concerns by developing a spatially varying system dynamics model as well as innovative global optimization search techniques to maximize outcomes from participatory dialogues. Ultimately, the core system architecture of CADRe also serves as the cornerstone upon which key scientific innovation and challenges can be addressed.« less
MacLeod, Colin; Grafton, Ben
2016-11-01
In this review of research concerning anxiety-linked attentional bias, we seek to illustrate a general principle that we contend applies across the breadth of experimental psychopathology. Specifically, we highlight how maintenance of a clear distinction between process and procedure serves to enhance the advancement of knowledge and understanding, while failure to maintain this distinction can foster confusion and misconception. We show how such clear differentiation has permitted the continuous refinement of assessment procedures, in ways that have led to growing confidence in the existence of the putative attentional bias process of interest, and also increasing understanding of its nature. In contrast, we show how a failure to consistently differentiate between process and procedure has contributed to confusion concerning whether or not attentional bias modification reliably alters anxiety vulnerability and dysfunction. As we demonstrate, such confusion can be avoided by distinguishing the process of attentional bias modification from the procedures that have been employed with the intention of evoking this target process. Such an approach reveals that procedures adopted with the intention of eliciting the attentional bias modification process do not always do so, but that successful evocation of the attentional bias modification process quite reliably alters anxiety symptomatology. We consider some of the specific implications for future research concerning attentional bias modification, while also pointing to the broader implications for experimental psychopathology research in general. Copyright © 2016 Elsevier Ltd. All rights reserved.
Condensing Raman spectrum for single-cell phenotype analysis.
Sun, Shiwei; Wang, Xuetao; Gao, Xin; Ren, Lihui; Su, Xiaoquan; Bu, Dongbo; Ning, Kang
2015-01-01
In recent years, high throughput and non-invasive Raman spectrometry technique has matured as an effective approach to identification of individual cells by species, even in complex, mixed populations. Raman profiling is an appealing optical microscopic method to achieve this. To fully utilize Raman proling for single-cell analysis, an extensive understanding of Raman spectra is necessary to answer questions such as which filtering methodologies are effective for pre-processing of Raman spectra, what strains can be distinguished by Raman spectra, and what features serve best as Raman-based biomarkers for single-cells, etc. In this work, we have proposed an approach called rDisc to discretize the original Raman spectrum into only a few (usually less than 20) representative peaks (Raman shifts). The approach has advantages in removing noises, and condensing the original spectrum. In particular, effective signal processing procedures were designed to eliminate noise, utilising wavelet transform denoising, baseline correction, and signal normalization. In the discretizing process, representative peaks were selected to signicantly decrease the Raman data size. More importantly, the selected peaks are chosen as suitable to serve as key biological markers to differentiate species and other cellular features. Additionally, the classication performance of discretized spectra was found to be comparable to full spectrum having more than 1000 Raman shifts. Overall, the discretized spectrum needs about 5storage space of a full spectrum and the processing speed is considerably faster. This makes rDisc clearly superior to other methods for single-cell classication.
NASA Astrophysics Data System (ADS)
Dizerens, Céline; Hüsler, Fabia; Wunderle, Stefan
2016-04-01
The spatial and temporal variability of snow cover has a significant impact on climate and environment and is of great socio-economic importance for the European Alps. Satellite remote sensing data is widely used to study snow cover variability and can provide spatially comprehensive information on snow cover extent. However, cloud cover strongly impedes the surface view and hence limits the number of useful snow observations. Outdoor webcam images not only offer unique potential for complementing satellite-derived snow retrieval under cloudy conditions but could also serve as a reference for improved validation of satellite-based approaches. Thousands of webcams are currently connected to the Internet and deliver freely available images with high temporal and spatial resolutions. To exploit the untapped potential of these webcams, a semi-automatic procedure was developed to generate snow cover maps based on webcam images. We used daily webcam images of the Swiss alpine region to apply, improve, and extend existing approaches dealing with the positioning of photographs within a terrain model, appropriate georectification, and the automatic snow classification of such photographs. In this presentation, we provide an overview of the implemented procedure and demonstrate how our registration approach automatically resolves the orientation of a webcam by using a high-resolution digital elevation model and the webcam's position. This allows snow-classified pixels of webcam images to be related to their real-world coordinates. We present several examples of resulting snow cover maps, which have the same resolution as the digital elevation model and indicate whether each grid cell is snow-covered, snow-free, or not visible from webcams' positions. The procedure is expected to work under almost any weather condition and demonstrates the feasibility of using webcams for the retrieval of high-resolution snow cover information.
Consensus building for interlaboratory studies, key comparisons, and meta-analysis
NASA Astrophysics Data System (ADS)
Koepke, Amanda; Lafarge, Thomas; Possolo, Antonio; Toman, Blaza
2017-06-01
Interlaboratory studies in measurement science, including key comparisons, and meta-analyses in several fields, including medicine, serve to intercompare measurement results obtained independently, and typically produce a consensus value for the common measurand that blends the values measured by the participants. Since interlaboratory studies and meta-analyses reveal and quantify differences between measured values, regardless of the underlying causes for such differences, they also provide so-called ‘top-down’ evaluations of measurement uncertainty. Measured values are often substantially over-dispersed by comparison with their individual, stated uncertainties, thus suggesting the existence of yet unrecognized sources of uncertainty (dark uncertainty). We contrast two different approaches to take dark uncertainty into account both in the computation of consensus values and in the evaluation of the associated uncertainty, which have traditionally been preferred by different scientific communities. One inflates the stated uncertainties by a multiplicative factor. The other adds laboratory-specific ‘effects’ to the value of the measurand. After distinguishing what we call recipe-based and model-based approaches to data reductions in interlaboratory studies, we state six guiding principles that should inform such reductions. These principles favor model-based approaches that expose and facilitate the critical assessment of validating assumptions, and give preeminence to substantive criteria to determine which measurement results to include, and which to exclude, as opposed to purely statistical considerations, and also how to weigh them. Following an overview of maximum likelihood methods, three general purpose procedures for data reduction are described in detail, including explanations of how the consensus value and degrees of equivalence are computed, and the associated uncertainty evaluated: the DerSimonian-Laird procedure; a hierarchical Bayesian procedure; and the Linear Pool. These three procedures have been implemented and made widely accessible in a Web-based application (NIST Consensus Builder). We illustrate principles, statistical models, and data reduction procedures in four examples: (i) the measurement of the Newtonian constant of gravitation; (ii) the measurement of the half-lives of radioactive isotopes of caesium and strontium; (iii) the comparison of two alternative treatments for carotid artery stenosis; and (iv) a key comparison where the measurand was the calibration factor of a radio-frequency power sensor.
Network-Based Management Procedures.
ERIC Educational Resources Information Center
Buckner, Allen L.
Network-based management procedures serve as valuable aids in organizational management, achievement of objectives, problem solving, and decisionmaking. Network techniques especially applicable to educational management systems are the program evaluation and review technique (PERT) and the critical path method (CPM). Other network charting…
A New Maximum Likelihood Approach for Free Energy Profile Construction from Molecular Simulations
Lee, Tai-Sung; Radak, Brian K.; Pabis, Anna; York, Darrin M.
2013-01-01
A novel variational method for construction of free energy profiles from molecular simulation data is presented. The variational free energy profile (VFEP) method uses the maximum likelihood principle applied to the global free energy profile based on the entire set of simulation data (e.g from multiple biased simulations) that spans the free energy surface. The new method addresses common obstacles in two major problems usually observed in traditional methods for estimating free energy surfaces: the need for overlap in the re-weighting procedure and the problem of data representation. Test cases demonstrate that VFEP outperforms other methods in terms of the amount and sparsity of the data needed to construct the overall free energy profiles. For typical chemical reactions, only ~5 windows and ~20-35 independent data points per window are sufficient to obtain an overall qualitatively correct free energy profile with sampling errors an order of magnitude smaller than the free energy barrier. The proposed approach thus provides a feasible mechanism to quickly construct the global free energy profile and identify free energy barriers and basins in free energy simulations via a robust, variational procedure that determines an analytic representation of the free energy profile without the requirement of numerically unstable histograms or binning procedures. It can serve as a new framework for biased simulations and is suitable to be used together with other methods to tackle with the free energy estimation problem. PMID:23457427
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Procedure when a demand is issued in a legal proceeding involving the United States. 1263.102 Section 1263.102 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION DEMAND FOR INFORMATION OR TESTIMONY SERVED ON AGENCY EMPLOYEES; PROCEDURES...
A Robust Adaptive Autonomous Approach to Optimal Experimental Design
NASA Astrophysics Data System (ADS)
Gu, Hairong
Experimentation is the fundamental tool of scientific inquiries to understand the laws governing the nature and human behaviors. Many complex real-world experimental scenarios, particularly in quest of prediction accuracy, often encounter difficulties to conduct experiments using an existing experimental procedure for the following two reasons. First, the existing experimental procedures require a parametric model to serve as the proxy of the latent data structure or data-generating mechanism at the beginning of an experiment. However, for those experimental scenarios of concern, a sound model is often unavailable before an experiment. Second, those experimental scenarios usually contain a large number of design variables, which potentially leads to a lengthy and costly data collection cycle. Incompetently, the existing experimental procedures are unable to optimize large-scale experiments so as to minimize the experimental length and cost. Facing the two challenges in those experimental scenarios, the aim of the present study is to develop a new experimental procedure that allows an experiment to be conducted without the assumption of a parametric model while still achieving satisfactory prediction, and performs optimization of experimental designs to improve the efficiency of an experiment. The new experimental procedure developed in the present study is named robust adaptive autonomous system (RAAS). RAAS is a procedure for sequential experiments composed of multiple experimental trials, which performs function estimation, variable selection, reverse prediction and design optimization on each trial. Directly addressing the challenges in those experimental scenarios of concern, function estimation and variable selection are performed by data-driven modeling methods to generate a predictive model from data collected during the course of an experiment, thus exempting the requirement of a parametric model at the beginning of an experiment; design optimization is performed to select experimental designs on the fly of an experiment based on their usefulness so that fewest designs are needed to reach useful inferential conclusions. Technically, function estimation is realized by Bayesian P-splines, variable selection is realized by Bayesian spike-and-slab prior, reverse prediction is realized by grid-search and design optimization is realized by the concepts of active learning. The present study demonstrated that RAAS achieves statistical robustness by making accurate predictions without the assumption of a parametric model serving as the proxy of latent data structure while the existing procedures can draw poor statistical inferences if a misspecified model is assumed; RAAS also achieves inferential efficiency by taking fewer designs to acquire useful statistical inferences than non-optimal procedures. Thus, RAAS is expected to be a principled solution to real-world experimental scenarios pursuing robust prediction and efficient experimentation.
NASA Astrophysics Data System (ADS)
Sudin, Azila M.; Sufahani, Suliadi
2018-04-01
Secondary school student need to eat a well nutritious and healthy food that gives enough supplements for improvement, safeguarding and rebuilding the human body. In addition, with legitimate supplement, it can keep any undesirable diseases and infections. At this moment, medicinal disclosure demonstrates that by expending very much adjusted nutritious sustenance, it can anticipate and decrease the dangers of certain illness. Menu organizers, nutritionist and dietitians faced with mind boggling undertakings and inconveniences obstacles to grow human wellbeing. Serving more beneficial meal is a noteworthy step towards accomplishing one of the objectives for this study. However reorganizing a nutritious and well balanced menu by hand is difficult, insufficient and time consuming. The target of this study is to build up a mathematical technique for menu scheduling that fulfill the whole supplement prerequisite for secondary school student, reduce processing time, minimize the budget and furthermore serve assortment type of food consistently. It additionally gives the adaptability for the cook to change any favored menu even after the ideal arrangement and optimal solution has been acquired. A recalculation procedure will be performed in light of the ideal arrangement. The data was obtained from the Ministry of Health Malaysian and school specialists. The model was solved by using Binary Programming and “Delete-Reshuffle-Reoptimize Algorithm”.
Analgesics as Reinforcers with Chronic Pain: Evidence from Operant Studies
Ewan, Eric E.; Martin, Thomas J.
2013-01-01
Previously preclinical pain research has focused on simple behavioral endpoints to assess the efficacy of analgesics in acute and chronic pain models, primarily reflexive withdrawal from an applied mechanical or thermal stimulus. However recent research has been aimed at investigating other behavioral states in the presence of pain, including spontaneous, non-elicited pain. One approach is to investigate the reinforcing effects of analgesics in animals with experimental pain, which should serve as reinforcers by virtue of their ability to alleviate the relevant subjective states induced by pain. The gold standard for assessing drug reinforcement is generally accepted to be drug self-administration, and this review highlights the ability of drugs to serve as reinforcers in animals with experimental neuropathic pain, and the extent to which this behavior is altered in chronic pain states. Additionally, intracranial self-stimulation is an operant procedure that has been used extensively to study drug reinforcement mechanisms and the manner in which neuropathic pain alters the ability of drugs to serve as reinforcers in this paradigm will also be discussed. Drug self-administration and intracranial self-stimulation have promise as tools to investigate behavioral effects of analgesics in animals with chronic pain, particularly regarding the mechanisms through which these drugs motivate consumption in a chronic pain state. PMID:23973302
A novel intra-operative, high-resolution atrial mapping approach.
Yaksh, Ameeta; van der Does, Lisette J M E; Kik, Charles; Knops, Paul; Oei, Frans B S; van de Woestijne, Pieter C; Bekkers, Jos A; Bogers, Ad J J C; Allessie, Maurits A; de Groot, Natasja M S
2015-12-01
A new technique is demonstrated for extensive high-resolution intra-operative atrial mapping that will facilitate the localization of atrial fibrillation (AF) sources and identification of the substrate perpetuating AF. Prior to the start of extra-corporal circulation, a 8 × 24-electrode array (2-mm inter-electrode distance) is placed subsequently on all the right and left epicardial atrial sites, including Bachmann's bundle, for recording of unipolar electrograms during sinus rhythm and (induced) AF. AF is induced by high-frequency pacing at the right atrial free wall. A pacemaker wire stitched to the right atrium serves as a reference signal. The indifferent pole is connected to a steal wire fixed to subcutaneous tissue. Electrograms are recorded by a computerized mapping system and, after amplification (gain 1000), filtering (bandwidth 0.5-400 Hz), sampling (1 kHz) and analogue to digital conversion (16 bits), automatically stored on hard disk. During the mapping procedure, real-time visualization secures electrogram quality. Analysis will be performed offline. This technique was performed in 168 patients of 18 years and older, with coronary and/or structural heart disease, with or without AF, electively scheduled for cardiac surgery and a ventricular ejection fraction above 40 %. The mean duration of the entire mapping procedure including preparation time was 9 ± 2 min. Complications related to the mapping procedure during or after cardiac surgery were not observed. We introduce the first epicardial atrial mapping approach with a high resolution of ≥1728 recording sites which can be performed in a procedure time of only 9±2 mins. This mapping technique can potentially identify areas responsible for initiation and persistence of AF and hopefully can individualize both diagnosis and therapy of AF.
Tandem catalysis for the preparation of cylindrical polypeptide brushes.
Rhodes, Allison J; Deming, Timothy J
2012-11-28
Here, we report a method for synthesis of cylindrical copolypeptide brushes via N-carboxyanhydride (NCA) polymerization utilizing a new tandem catalysis approach that allows preparation of brushes with controlled segment lengths in a straightforward, one-pot procedure requiring no intermediate isolation or purification steps. To obtain high-density brush copolypeptides, we used a "grafting from" approach where alloc-α-aminoamide groups were installed onto the side chains of NCAs to serve as masked initiators. These groups were inert during cobalt-initiated NCA polymerization and gave allyloxycarbonyl-α-aminoamide-substituted polypeptide main chains. The alloc-α-aminoamide groups were then activated in situ using nickel to generate initiators for growth of side-chain brush segments. This use of stepwise tandem cobalt and nickel catalysis was found to be an efficient method for preparation of high-chain-density, cylindrical copolypeptide brushes, where both the main chains and side chains can be prepared with controlled segment lengths.
Fedotchev, A I
2010-01-01
The perspective approach to non-pharmacological correction of the stress induced functional disorders in humans, based on the double negative feedback from patient's EEG was validated and experimentally tested. The approach implies a simultaneous use of narrow frequency EEG-oscillators, characteristic for each patient and recorded in real time span, in two independent contours of negative feedback--traditional contour of adaptive biomanagement and additional contour of resonance stimulation. In the last the signals of negative feedback from individual narrow frequency EEG oscillators are not recognized by the subject, but serve for an automatic modulation of the parameters of the sensory impact. Was shown that due to combination of active (conscious perception) and passive (automatic modulation) use of signals of negative feedback from narrow frequency EEG components of the patient, opens a possibility of considerable increase of efficiency of the procedures of EEG biomanagement.
Optical authentication based on moiré effect of nonlinear gratings in phase space
NASA Astrophysics Data System (ADS)
Liao, Meihua; He, Wenqi; Wu, Jiachen; Lu, Dajiang; Liu, Xiaoli; Peng, Xiang
2015-12-01
An optical authentication scheme based on the moiré effect of nonlinear gratings in phase space is proposed. According to the phase function relationship of the moiré effect in phase space, an arbitrary authentication image can be encoded into two nonlinear gratings which serve as the authentication lock (AL) and the authentication key (AK). The AL is stored in the authentication system while the AK is assigned to the authorized user. The authentication procedure can be performed using an optoelectronic approach, while the design process is accomplished by a digital approach. Furthermore, this optical authentication scheme can be extended for multiple users with different security levels. The proposed scheme can not only verify the legality of a user identity, but can also discriminate and control the security levels of legal users. Theoretical analysis and simulation experiments are provided to verify the feasibility and effectiveness of the proposed scheme.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 10 Energy 4 2012-01-01 2012-01-01 false Service. 501.6 Section 501.6 Energy DEPARTMENT OF ENERGY (CONTINUED) ALTERNATE FUELS ADMINISTRATIVE PROCEDURES AND SANCTIONS General Provisions § 501.6 Service. (a) DOE will serve all orders, notices interpretations or other documents that it is required to serve...
37 CFR 205.13 - Complaints served on the Register of Copyrights pursuant to 17 U.S.C. 411(a).
Code of Federal Regulations, 2010 CFR
2010-07-01
... Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT OFFICE AND PROCEDURES LEGAL PROCESSES Service of Process § 205.13 Complaints served on the Register of Copyrights pursuant to 17 U.S.C. 411(a). When an...
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 4 2010-01-01 2010-01-01 false Service. 501.6 Section 501.6 Energy DEPARTMENT OF ENERGY (CONTINUED) ALTERNATE FUELS ADMINISTRATIVE PROCEDURES AND SANCTIONS General Provisions § 501.6 Service. (a) DOE will serve all orders, notices interpretations or other documents that it is required to serve...
Code of Federal Regulations, 2010 CFR
2010-07-01
... Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED... Secretary determines that different policies or procedures would better serve the objectives of the Act, such policies or procedures may be modified upon appropriate notice to any persons affected by the...
A novel approach to EPID-based 3D volumetric dosimetry for IMRT and VMAT QA
NASA Astrophysics Data System (ADS)
Alhazmi, Abdulaziz; Gianoli, Chiara; Neppl, Sebastian; Martins, Juliana; Veloza, Stella; Podesta, Mark; Verhaegen, Frank; Reiner, Michael; Belka, Claus; Parodi, Katia
2018-06-01
Intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) are relatively complex treatment delivery techniques and require quality assurance (QA) procedures. Pre-treatment dosimetric verification represents a fundamental QA procedure in daily clinical routine in radiation therapy. The purpose of this study is to develop an EPID-based approach to reconstruct a 3D dose distribution as imparted to a virtual cylindrical water phantom to be used for plan-specific pre-treatment dosimetric verification for IMRT and VMAT plans. For each depth, the planar 2D dose distributions acquired in air were back-projected and convolved by depth-specific scatter and attenuation kernels. The kernels were obtained by making use of scatter and attenuation models to iteratively estimate the parameters from a set of reference measurements. The derived parameters served as a look-up table for reconstruction of arbitrary measurements. The summation of the reconstructed 3D dose distributions resulted in the integrated 3D dose distribution of the treatment delivery. The accuracy of the proposed approach was validated in clinical IMRT and VMAT plans by means of gamma evaluation, comparing the reconstructed 3D dose distributions with Octavius measurement. The comparison was carried out using (3%, 3 mm) criteria scoring 99% and 96% passing rates for IMRT and VMAT, respectively. An accuracy comparable to the one of the commercial device for 3D volumetric dosimetry was demonstrated. In addition, five IMRT and five VMAT were validated against the 3D dose calculation performed by the TPS in a water phantom using the same passing rate criteria. The median passing rates within the ten treatment plans was 97.3%, whereas the lowest was 95%. Besides, the reconstructed 3D distribution is obtained without predictions relying on forward dose calculation and without external phantom or dosimetric devices. Thus, the approach provides a fully automated, fast and easy QA procedure for plan-specific pre-treatment dosimetric verification.
Cross-infection risks associated with current procedures for using high-speed dental handpieces.
Lewis, D L; Boe, R K
1992-01-01
When a dye solution used to simulate patient material was either injected into high-speed dental handpiece (drill) waterlines or applied to the equipment externally, internal air turbine chambers became contaminated. These chambers served as a reservoir of the material, which was slowly dislodged by air expelled during subsequent handpiece operation and which was diluted by water spray used for cooling the drilling surface. Considering the fact that patient materials could reside in internal parts of the equipment that are not usually disinfected and that the material may be subsequently sprayed into cuts and abrasions in the oral cavity, the common approach to reprocessing handpieces (external wiping in combination with flushing) may pose unacceptably high risks to those individuals treated soon after infected patients. Therefore, unless reliable data on cross-infection frequencies are obtained and prove it unnecessary, heat-treating high-speed handpieces between each patient should be considered an essential component of standard procedures whenever universal precautions are practiced in dentistry. PMID:1537909
TAS: A Transonic Aircraft/Store flow field prediction code
NASA Technical Reports Server (NTRS)
Thompson, D. S.
1983-01-01
A numerical procedure has been developed that has the capability to predict the transonic flow field around an aircraft with an arbitrarily located, separated store. The TAS code, the product of a joint General Dynamics/NASA ARC/AFWAL research and development program, will serve as the basis for a comprehensive predictive method for aircraft with arbitrary store loadings. This report described the numerical procedures employed to simulate the flow field around a configuration of this type. The validity of TAS code predictions is established by comparison with existing experimental data. In addition, future areas of development of the code are outlined. A brief description of code utilization is also given in the Appendix. The aircraft/store configuration is simulated using a mesh embedding approach. The computational domain is discretized by three meshes: (1) a planform-oriented wing/body fine mesh, (2) a cylindrical store mesh, and (3) a global Cartesian crude mesh. This embedded mesh scheme enables simulation of stores with fins of arbitrary angular orientation.
Health systems: changes in hospital efficiency and profitability.
Büchner, Vera Antonia; Hinz, Vera; Schreyögg, Jonas
2016-06-01
This study investigates potential changes in hospital performance after health system entry, while differentiating between hospital technical and cost efficiency and hospital profitability. In the first stage we obtained (bootstrapped) data envelopment analysis (DEA) efficiency scores. Then, genetic matching is used as a novel matching procedure in this context along with a difference-in-difference approach within a panel regression framework. With the genetic matching procedure, independent and health system hospitals are matched along a number of environmental and organizational characteristics. The results show that health system entry increases hospital technical and cost efficiency by between 0.6 and 3.4 % in four alternative post-entry periods, indicating that health system entry has not a transitory but rather a permanent effect on hospital efficiency. Regarding hospital profitability, the results reveal an increase in hospital profitability only 1 year after health system entry, and the estimations suggest that this effect is a transitional phenomenon. Overall, health system entry may serve as an appropriate management instrument for decision makers to increase hospital performance.
Effectively Transforming IMC Flight into VMC Flight: An SVS Case Study
NASA Technical Reports Server (NTRS)
Glaab, Louis J.; Hughes, Monic F.; Parrish, Russell V.; Takallu, Mohammad A.
2006-01-01
A flight-test experiment was conducted using the NASA LaRC Cessna 206 aircraft. Four primary flight and navigation display concepts, including baseline and Synthetic Vision System (SVS) concepts, were evaluated in the local area of Roanoke Virginia Airport, flying visual and instrument approach procedures. A total of 19 pilots, from 3 pilot groups reflecting the diverse piloting skills of the GA population, served as evaluation pilots. Multi-variable Discriminant Analysis was applied to three carefully selected and markedly different operating conditions with conventional instrumentation to provide an extension of traditional analysis methods as well as provide an assessment of the effectiveness of SVS displays to effectively transform IMC flight into VMC flight.
Aircraft electromagnetic compatibility
NASA Technical Reports Server (NTRS)
Clarke, Clifton A.; Larsen, William E.
1987-01-01
Illustrated are aircraft architecture, electromagnetic interference environments, electromagnetic compatibility protection techniques, program specifications, tasks, and verification and validation procedures. The environment of 400 Hz power, electrical transients, and radio frequency fields are portrayed and related to thresholds of avionics electronics. Five layers of protection for avionics are defined. Recognition is given to some present day electromagnetic compatibility weaknesses and issues which serve to reemphasize the importance of EMC verification of equipment and parts, and their ultimate EMC validation on the aircraft. Proven standards of grounding, bonding, shielding, wiring, and packaging are laid out to help provide a foundation for a comprehensive approach to successful future aircraft design and an understanding of cost effective EMC in an aircraft setting.
Improved Cryopreservation of Human Umbilical Vein Endothelial Cells: A Systematic Approach
NASA Astrophysics Data System (ADS)
Sultani, A. Billal; Marquez-Curtis, Leah A.; Elliott, Janet A. W.; McGann, Locksley E.
2016-10-01
Cryopreservation of human umbilical vein endothelial cells (HUVECs) facilitated their commercial availability for use in vascular biology, tissue engineering and drug delivery research; however, the key variables in HUVEC cryopreservation have not been comprehensively studied. HUVECs are typically cryopreserved by cooling at 1 °C/min in the presence of 10% dimethyl sulfoxide (DMSO). We applied interrupted slow cooling (graded freezing) and interrupted rapid cooling with a hold time (two-step freezing) to identify where in the cooling process cryoinjury to HUVECs occurs. We found that linear cooling at 1 °C/min resulted in higher membrane integrities than linear cooling at 0.2 °C/min or nonlinear two-step freezing. DMSO addition procedures and compositions were also investigated. By combining hydroxyethyl starch with DMSO, HUVEC viability after cryopreservation was improved compared to measured viabilities of commercially available cryopreserved HUVECs and viabilities for HUVEC cryopreservation studies reported in the literature. Furthermore, HUVECs cryopreserved using our improved procedure showed high tube forming capability in a post-thaw angiogenesis assay, a standard indicator of endothelial cell function. As well as presenting superior cryopreservation procedures for HUVECs, the methods developed here can serve as a model to optimize the cryopreservation of other cells.
49 CFR 511.32 - Written interrogatories to parties.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 6 2010-10-01 2010-10-01 false Written interrogatories to parties. 511.32 Section... Process § 511.32 Written interrogatories to parties. (a) Availability; procedures for use. Any party may serve upon any other party written interrogatories to be answered by the party served or, if the party...
77 FR 66443 - Renewal of the Defense Health Board
Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-05
... an annual basis according to DoD policy and procedures. Board members who are not full-time or permanent part-time Federal employees shall be appointed to serve as experts and consultants under the... exception of travel and per diem for official travel, Board members shall serve without compensation. The...
Pediatric Integrative Medicine Approaches to Attention Deficit Hyperactivity Disorder (ADHD)
Esparham, Anna; Evans, Randall G.; Wagner, Leigh E.; Drisko, Jeanne A.
2014-01-01
Attention deficit hyperactivity disorder (ADHD) is the most common neuropsychiatric disorder in children and is increasing in prevalence. There has also been a related increase in prescribing stimulant medication despite some controversy whether ADHD medication makes a lasting difference in school performance or achievement. Families who are apprehensive about side effects and with concerns for efficacy of medication pursue integrative medicine as an alternative or adjunct to pharmacologic and cognitive behavioral treatment approaches. Integrative medicine incorporates evidence-based medicine, both conventional and complementary and alternative therapies, to deliver personalized care to the patient, emphasizing diet, nutrients, gut health, and environmental influences as a means to decrease symptoms associated with chronic disorders. Pediatric integrative medicine practitioners are increasing in number throughout the United States because of improvement in patient health outcomes. However, limited funding and poor research design interfere with generalizable treatment approaches utilizing integrative medicine. The use of research designs originally intended for drugs and procedures are not suitable for many integrative medicine approaches. This article serves to highlight integrative medicine approaches in use today for children with ADHD, including dietary therapies, nutritional supplements, environmental hygiene, and neurofeedback. PMID:27417475
Guy, Elizabeth Glenn; Fletcher, Paul J
2014-06-01
Nicotine enhances approach toward and operant responding for conditioned stimuli (CSs), but the effect of exposure during different phases of Pavlovian incentive learning on these measures remains to be determined. These studies examined the effects of administering nicotine early, late or throughout Pavlovian conditioning trials on discriminated approach behavior, nicotine-enhanced responding for conditioned reinforcement, extinction, and the reinstatement of responding for conditioned reinforcement. We also tested the effect of nicotine on approach to a lever-CS in a Pavlovian autoshaping procedure and for this CS to serve as a conditioned reinforcer. Thirsty rats were exposed to 13 conditioning sessions where a light/tone CS was paired with the delivery of water. Nicotine was administered either prior to the first or last seven sessions, or throughout the entire conditioning procedure. Responding for conditioned reinforcement, extinction, and the reinstatement of responding by the stimulus and nicotine were compared across exposure groups. Separately, the effects of nicotine on conditioned approach toward a lever-CS during autoshaping, and responding for that CS as a conditioned reinforcer, were examined. Nicotine exposure was necessary for nicotine-enhanced responding for conditioned reinforcement and the ability for nicotine and the stimulus to additively reinstate responding on the reinforced lever. Nicotine increased contacts with a lever-CS during autoshaping, and removal of nicotine abolished this effect. Prior nicotine exposure was necessary for nicotine-enhanced responding reinforced by the lever. Enhancements in the motivating properties of CSs by nicotine occur independently from duration and timing effects of nicotine exposure during conditioning.
Multivariate Cluster Analysis.
ERIC Educational Resources Information Center
McRae, Douglas J.
Procedures for grouping students into homogeneous subsets have long interested educational researchers. The research reported in this paper is an investigation of a set of objective grouping procedures based on multivariate analysis considerations. Four multivariate functions that might serve as criteria for adequate grouping are given and…
Code of Federal Regulations, 2010 CFR
2010-10-01
... MARITIME COMMISSION GENERAL AND ADMINISTRATIVE PROVISIONS RULES OF PRACTICE AND PROCEDURE Formal Procedure... of the administrative law judge, notices of review, and Commission decisions shall be served by the administrative law judge or the Commission. All other pleadings, documents and filings shall, when tendered to...
Code of Federal Regulations, 2010 CFR
2010-04-01
... § 350.3 Procedure. (a) Service of legal process brought for the enforcement of an individual's... General Counsel is effectively served with legal process relating to an individual's legal obligation to... under the social security minimum guaranty provision of the Railroad Retirement Act. (c) Included with...
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Procedures. 32.1004 Section 32.1004 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING... performance-based payments are contract financing, events or criteria shall not serve as a vehicle to reward...
29 CFR 2.24 - Procedure in the event of an adverse ruling.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 29 Labor 1 2014-07-01 2013-07-01 true Procedure in the event of an adverse ruling. 2.24 Section 2.24 Labor Office of the Secretary of Labor GENERAL REGULATIONS Employees Served With Subpoenas § 2.24 Procedure in the event of an adverse ruling. If the court or other authority declines to stay the effect of...
Pattern Recognition in Optical Remote Sensing Data Processing
NASA Astrophysics Data System (ADS)
Kozoderov, Vladimir; Kondranin, Timofei; Dmitriev, Egor; Kamentsev, Vladimir
Computational procedures of the land surface biophysical parameters retrieval imply that modeling techniques are available of the outgoing radiation description together with monitoring techniques of remote sensing data processing using registered radiances between the related optical sensors and the land surface objects called “patterns”. Pattern recognition techniques are a valuable approach to the processing of remote sensing data for images of the land surface - atmosphere system. Many simplified codes of the direct and inverse problems of atmospheric optics are considered applicable for the imagery processing of low and middle spatial resolution. Unless the authors are not interested in the accuracy of the final information products, they utilize these standard procedures. The emerging necessity of processing data of high spectral and spatial resolution given by imaging spectrometers puts forward the newly defined pattern recognition techniques. The proposed tools of using different types of classifiers combined with the parameter retrieval procedures for the forested environment are maintained to have much wider applications as compared with the image features and object shapes extraction, which relates to photometry and geometry in pixel-level reflectance representation of the forested land cover. The pixel fraction and reflectance of “end-members” (sunlit forest canopy, sunlit background and shaded background for a particular view and solar illumination angle) are only a part in the listed techniques. It is assumed that each pixel views collections of the individual forest trees and the pixel-level reflectance can thus be computed as a linear mixture of sunlit tree tops, sunlit background (or understory) and shadows. Instead of these photometry and geometry constraints, the improved models are developed of the functional description of outgoing spectral radiation, in which such parameters of the forest canopy like the vegetation biomass density for particular forest species and age are embedded. This permits us to calculate the relationships between the registered radiances and the biomass densities (the direct problem of atmospheric optics). The next stage is to find solutions of this problem as cross-sections of the related curves in the multi-dimensional space given by the parameters of these models (the inverse problem). The typical solutions may not be mathematically unique and the computational procedure is undertaken to their regularization by finding minima of the functional called “the energy for the particular class of forests”. The relevant optimization procedures serve to identify the likelihood between any registered set of data and the theoretical distributions as well as to regularize the solution by employing the derivative functions characterizing the neighborhood of the pixels for the related classes. As a result, we have elaborated a rigorous approach to optimize spectral channels based on searching their most informative sets by combining the channels and finding correlations between them. A successive addition method is used with the calculation of the total probability error. The step up method consists in fixing the level of the probability error that is not improved by further adding the channels in the calculation scheme of the pattern recognition. The best distinguishable classes are recognized at the first stage of this procedure. The analytical technique called “cross-validation” is used at its second stage. This procedure is in removing some data before the classifier training begins employing, for instance, the known “leaving-out-one” strategy. This strategy serves to explain the accuracy category additionally to the standard confusion matrix between the modeling approach and the available ground-based observations, once the employed validation map may not be perfect or needs renewal. Such cross-validation carried out for ensembles of airborne data from the imaging spectrometer produced in Russia enables to conclude that the forest classes on a test area are separated with high accuracy. The proposed approach is recommended to account for the needed set of ground-based measurements during field campaigns for the validation purposes of remote sensing data processing and for the retrieval procedures of such parameters of forests like Net Primary Productivity with an ensured accuracy that results from the described here computational procedures.
The Fruit & Vegetable Screener in the 2000 California Health Interview Survey: Scoring Procedures
Scoring procedures were developed to convert the individual respondent's screener responses to estimates of individual dietary intake for servings of fruits and vegetables using USDA's 1994-96 Continuing Survey of Food Intakes of Individuals (CSFII 94-96) dietary recall data.
7 CFR 220.11 - Reimbursement procedures.
Code of Federal Regulations, 2010 CFR
2010-01-01
... AGRICULTURE CHILD NUTRITION PROGRAMS SCHOOL BREAKFAST PROGRAM § 220.11 Reimbursement procedures. (a) To be... by FNS, the Claim for Reimbursement for any month shall include only breakfasts served in that month... Lunch Program and the School Breakfast Program, the State agency or FNSRO, where applicable, may...
7 CFR 220.11 - Reimbursement procedures.
Code of Federal Regulations, 2011 CFR
2011-01-01
... AGRICULTURE CHILD NUTRITION PROGRAMS SCHOOL BREAKFAST PROGRAM § 220.11 Reimbursement procedures. (a) To be... by FNS, the Claim for Reimbursement for any month shall include only breakfasts served in that month... Lunch Program and the School Breakfast Program, the State agency or FNSRO, where applicable, may...
Diet Screener in the 2005 CHIS: Scoring Procedures
Scoring procedures were developed to convert the individual respondent's screener responses to estimates of individual dietary intake for servings of fruits and vegetables and teaspoons of added sugar using USDA's 1994-96 Continuing Survey of Food Intakes of Individuals (CSFII 94-96) dietary recall data.
47 CFR 2.915 - Grant of application.
Code of Federal Regulations, 2012 CFR
2012-10-01
... RULES AND REGULATIONS Equipment Authorization Procedures Application Procedures for Equipment... officially notice, that: (1) The equipment is capable of complying with pertinent technical standards of the rule part(s) under which it is to be operated; and, (2) A grant of the application would serve the...
47 CFR 2.915 - Grant of application.
Code of Federal Regulations, 2010 CFR
2010-10-01
... RULES AND REGULATIONS Equipment Authorization Procedures Application Procedures for Equipment... officially notice, that: (1) The equipment is capable of complying with pertinent technical standards of the rule part(s) under which it is to be operated; and, (2) A grant of the application would serve the...
Handbook on: Rights, Responsibilities, Procedures.
ERIC Educational Resources Information Center
Illinois State Dept. of Rehabilitation Services, Springfield.
This handbook presents policies and procedures that affect three schools operated by the Illinois Department of Rehabilitation Services to serve students with disabilities: the Illinois Center for Rehabilitation and Education-Roosevelt, Illinois School for the Deaf, and the Illinois School for the Visually Impaired. The handbook includes…
[Civil, criminal and ethical liability of medical doctors].
Udelsmann, Artur
2002-01-01
In the last years doctors have been the target of a growing number of civil, criminal law suits, as well as ethical procedures. Medicine is a widely targeted career, not only owing to its inherent risks, but also owing to a mistaken approach of the Judiciary Power about the obligations of medical doctors. Decisions of the Medical Board in ethical procedures have an impact in civil and criminal justice and therefore should be followed closely. The purpose of this review is to provide a wide view from a doctor-lawyer perspective of cases involving civil, criminal liability of anesthesiologists as well as ethical procedures against them, in an effort to make them comprehensible to doctors. After a brief historical introduction civil liability foundations and legal articles are examined. Responsibilities of doctors, hospitals and health insurance providers are discussed separately, as well as reparation mechanisms. Crimes possible to occur during medical practice and respective penalties are described; the direct relationship between crime and civil reparation is demonstrated. The administrative nature of ethical procedure is described, emphasizing that the legal character of its penalties often serve as grounds for civil and criminal justice decisions. Prevention is still the best medicine. Good medical practice and a good medical-patient relationship are still the best ways to minimize lawsuits and their repercussions. Doctors should have some knowledge of juridical mechanisms in lawsuits and ethical procedures, but should not take defense initiatives without prior consultation of an attorney. Civil, criminal and ethical liability of physicians.
Automated use of mutagenesis data in structure prediction.
Nanda, Vikas; DeGrado, William F
2005-05-15
In the absence of experimental structural determination, numerous methods are available to indirectly predict or probe the structure of a target molecule. Genetic modification of a protein sequence is a powerful tool for identifying key residues involved in binding reactions or protein stability. Mutagenesis data is usually incorporated into the modeling process either through manual inspection of model compatibility with empirical data, or through the generation of geometric constraints linking sensitive residues to a binding interface. We present an approach derived from statistical studies of lattice models for introducing mutation information directly into the fitness score. The approach takes into account the phenotype of mutation (neutral or disruptive) and calculates the energy for a given structure over an ensemble of sequences. The structure prediction procedure searches for the optimal conformation where neutral sequences either have no impact or improve stability and disruptive sequences reduce stability relative to wild type. We examine three types of sequence ensembles: information from saturation mutagenesis, scanning mutagenesis, and homologous proteins. Incorporating multiple sequences into a statistical ensemble serves to energetically separate the native state and misfolded structures. As a result, the prediction of structure with a poor force field is sufficiently enhanced by mutational information to improve accuracy. Furthermore, by separating misfolded conformations from the target score, the ensemble energy serves to speed up conformational search algorithms such as Monte Carlo-based methods. Copyright 2005 Wiley-Liss, Inc.
Preventing Student Expulsions through Policies, and Procedures for At-Risk Students
ERIC Educational Resources Information Center
Smith, Michael Dale
2012-01-01
Staff members working at alternative schools must use best practices to effectively serve at-risk students and reduce expulsion rates. Expulsion is directly linked to high school dropout rates, with subsequent social costs. Today's alternative schools serve at-risk students who exhibit problematic behaviors, providing them an opportunity to…
49 CFR 1503.413 - Notice of Proposed Civil Penalty.
Code of Federal Regulations, 2010 CFR
2010-10-01
... AND ENFORCEMENT PROCEDURES Assessment of Civil Penalties by TSA § 1503.413 Notice of Proposed Civil Penalty. (a) Issuance. TSA may initiate a civil penalty action under this section by serving a Notice of Proposed Civil Penalty on the person charged with a violation of a TSA requirement. TSA will serve the...
Don't Guess About Drugs When You Can Have the Facts.
ERIC Educational Resources Information Center
National Inst. of Mental Health (DHEW), Bethesda, MD.
This catalogue serves two purposes. First, it outlines the general activities and materials in the National Institute of Mental Health anti-drug campaign. Second, it serves as an order form for materials that are currently available and describes the special procedures which have been established to facilitate distribution. Both radio and…
Can counterproductive work behaviors be productive? CWB as emotion-focused coping.
Krischer, Mindy M; Penney, Lisa M; Hunter, Emily M
2010-04-01
The goal of our study was to determine whether some forms of counterproductive work behavior (CWB) may serve to benefit employees. Building on the stressor-strain framework and theories of coping, we investigated whether two forms of CWB, production deviance and withdrawal, serve as a means of coping to mitigate the impact of low distributive and procedural justice on emotional exhaustion. Results from a survey of 295 employed persons from around the United States suggest that production deviance and withdrawal may benefit employees by reducing emotional exhaustion in the face of low distributive justice but not necessarily low procedural justice. Copyright 2010 APA, all rights reserved.
10 CFR 824.10 - Hearing Officer.
Code of Federal Regulations, 2013 CFR
2013-01-01
... OF ENERGY PROCEDURAL RULES FOR THE ASSESSMENT OF CIVIL PENALTIES FOR CLASSIFIED INFORMATION SECURITY... when the ends of justice would be served; (g) Conducts the hearing in a manner which is fair and... parties; (i) Disposes of procedural requests or similar matters; (j) Requires production of documents; and...
10 CFR 824.10 - Hearing Officer.
Code of Federal Regulations, 2010 CFR
2010-01-01
... OF ENERGY PROCEDURAL RULES FOR THE ASSESSMENT OF CIVIL PENALTIES FOR CLASSIFIED INFORMATION SECURITY... when the ends of justice would be served; (g) Conducts the hearing in a manner which is fair and... parties; (i) Disposes of procedural requests or similar matters; (j) Requires production of documents; and...
10 CFR 824.10 - Hearing Officer.
Code of Federal Regulations, 2014 CFR
2014-01-01
... OF ENERGY PROCEDURAL RULES FOR THE ASSESSMENT OF CIVIL PENALTIES FOR CLASSIFIED INFORMATION SECURITY... when the ends of justice would be served; (g) Conducts the hearing in a manner which is fair and... parties; (i) Disposes of procedural requests or similar matters; (j) Requires production of documents; and...
10 CFR 824.10 - Hearing Officer.
Code of Federal Regulations, 2012 CFR
2012-01-01
... OF ENERGY PROCEDURAL RULES FOR THE ASSESSMENT OF CIVIL PENALTIES FOR CLASSIFIED INFORMATION SECURITY... when the ends of justice would be served; (g) Conducts the hearing in a manner which is fair and... parties; (i) Disposes of procedural requests or similar matters; (j) Requires production of documents; and...
Cour, F; Vidart, A
2016-07-01
The never ending debate over the surgical approach of genital prolapse repair (abdominal versus vaginal route) is as passionate as ever. The available literature may support a multidisciplinary analysis of our expert daily practice. Our purpose was to define selection criteria for surgical approach between abdominal and vaginal route in the management of genital prolapse by reviewing the literature. Systematically review of the literature concerning comparative anatomical and functionnal results of surgery of pelvic organ prolaps by vaginal or abdominal route. We were confronted to the lack of data in the literature, with few prospective randomized comparative studies. Many limitations were identified such as small populations in the studies, no description of sub-population, multiplicity of surgical procedures. Moreover, vaginal route was compared to sacral colpopexy by open abdominal approach, whereas laparoscopic sacrocolpopexy is now recommended. Only one prospective randomized comparative trial assessed laparoscopic sacrocolpopexy and vaginal approach, in which was used a mesh withdrawn from the market. The lack of available randomized trials makes it impossible to define HAS compliant guidelines on this topic. However, selection criteria for each surgical approach and technique were drawn from experts' advices. © 2016 Published by Elsevier Masson SAS. © 2016 Elsevier Masson SAS. Tous droits réservés.
Casting a Wider Net: Data Driven Discovery of Proxies for Target Diagnoses
Ramljak, Dusan; Davey, Adam; Uversky, Alexey; Roychoudhury, Shoumik; Obradovic, Zoran
2015-01-01
Background: The Hospital Readmissions Reduction Program (HRRP) introduced in October 2012 as part of the Affordable Care Act (ACA), ties hospital reimbursement rates to adjusted 30-day readmissions and mortality performance for a small set of target diagnoses. There is growing concern and emerging evidence that use of a small set of target diagnoses to establish reimbursement rates can lead to unstable results that are susceptible to manipulation (gaming) by hospitals. Methods: We propose a novel approach to identifying co-occurring diagnoses and procedures that can themselves serve as a proxy indicator of the target diagnosis. The proposed approach constructs a Markov Blanket that allows a high level of performance, in terms of predictive accuracy and scalability, along with interpretability of obtained results. In order to scale to a large number of co-occuring diagnoses (features) and hospital discharge records (samples), our approach begins with Google’s PageRank algorithm and exploits the stability of obtained results to rank the contribution of each diagnosis/procedure in terms of presence in a Markov Blanket for outcome prediction. Results: Presence of target diagnoses acute myocardial infarction (AMI), congestive heart failure (CHF), pneumonia (PN), and Sepsis in hospital discharge records for Medicare and Medicaid patients in California and New York state hospitals (2009–2011), were predicted using models trained on a subset of California state hospitals (2003–2008). Using repeated holdout evaluation, we used ~30,000,000 hospital discharge records and analyzed the stability of the proposed approach. Model performance was measured using the Area Under the ROC Curve (AUC) metric, and importance and contribution of single features to the final result. The results varied from AUC=0.68 (with SE<1e-4) for PN on cross validation datasets to AUC=0.94, with (SE<1e-7) for Sepsis on California hospitals (2009 – 2011), while the stability of features was consistently better with more training data for each target diagnosis. Prediction accuracy for considered target diagnoses approaches or exceeds accuracy estimates for discharge record data. Conclusions: This paper presents a novel approach to identifying a small subset of relevant diagnoses and procedures that approximate the Markov Blanket for target diagnoses. Accuracy and interpretability of results demonstrate the potential of our approach. PMID:26958243
78 FR 47047 - Proposed Policy for Discontinuance of Certain Instrument Approach Procedures
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-02
... procedures. Localizer procedures. TACAN procedures. Standard Instrument Arrivals (STARs). Standard Instrument... Policy for Discontinuance of Certain Instrument Approach Procedures AGENCY: Federal Aviation... facilitates the introduction of area navigation (RNAV) instrument approach procedures over the past decade...
Potential and limitations of webcam images for snow cover monitoring in the Swiss Alps
NASA Astrophysics Data System (ADS)
Dizerens, Céline; Hüsler, Fabia; Wunderle, Stefan
2017-04-01
In Switzerland, several thousands of outdoor webcams are currently connected to the Internet. They deliver freely available images that can be used to analyze snow cover variability on a high spatio-temporal resolution. To make use of this big data source, we have implemented a webcam-based snow cover mapping procedure, which allows to almost automatically derive snow cover maps from such webcam images. As there is mostly no information about the webcams and its parameters available, our registration approach automatically resolves these parameters (camera orientation, principal point, field of view) by using an estimate of the webcams position, the mountain silhouette, and a high-resolution digital elevation model (DEM). Combined with an automatic snow classification and an image alignment using SIFT features, our procedure can be applied to arbitrary images to generate snow cover maps with a minimum of effort. Resulting snow cover maps have the same resolution as the digital elevation model and indicate whether each grid cell is snow-covered, snow-free, or hidden from webcams' positions. Up to now, we processed images of about 290 webcams from our archive, and evaluated images of 20 webcams using manually selected ground control points (GCPs) to evaluate the mapping accuracy of our procedure. We present methodological limitations and ongoing improvements, show some applications of our snow cover maps, and demonstrate that webcams not only offer a great opportunity to complement satellite-derived snow retrieval under cloudy conditions, but also serve as a reference for improved validation of satellite-based approaches.
Qualitative research: comments and controversies.
Schutz, R W
1989-03-01
Larry Locke's timely and well-written introduction to qualitative research procedures will undoubtedly serve its purpose. It makes us reassess our traditional beliefs and practices, educates us on the rudiments of qualitative methodology, and, hopefully, makes us more tolerant and appreciative of alternate ways of conducting research. Although Locke focuses his paper on pedagogical research issues, it is important to realize that many other sub-disciplines within the general field of physical education also utilize qualitative procedures. For example, 10 years ago Martens (1979) called for a paradigm shift in sport psychology by appealing to researchers to abandon their labs and to embark on naturalistic field studies. While North American sport psychologists, and psychologists in general, have been slow to formalize qualitative techniques, the European psychology community has been much more active (e.g., Ashworth, Giorgi, & de Koning, 1986). Perhaps Locke's article will encourage researchers in all our sub-disciplines to consider the utility of qualitative research. Hopefully, readers will treat Locke's article as an introduction to the broad area of qualitative research and not as a rigorous set of procedures for conducting participant observation research in school physical education studies. Additionally, it must be recognized that there are other approaches and other applications, that the area has its critics and its unresolved methodological problems, and that qualitative research does not necessarily exclude the application of formalized data analyses. Keeping these issues in mind, the addition of qualitative approaches to our repetoire of research methodologies can only enhance the quality of research in physical education and exercise and sport science.
14 CFR 16.201 - Notice and order of hearing.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 16.201 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PROCEDURAL... hearing will issue and serve on the respondent and complainant a hearing order. The hearing order will set..., and other authorities; (3) The issues to be decided; (4) Such rules of procedure as may be necessary...
14 CFR 16.201 - Notice and order of hearing.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 16.201 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PROCEDURAL... hearing will issue and serve on the respondent and complainant a hearing order. The hearing order will set..., and other authorities; (3) The issues to be decided; (4) Such rules of procedure as may be necessary...
14 CFR 16.201 - Notice and order of hearing.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 16.201 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PROCEDURAL... hearing will issue and serve on the respondent and complainant a hearing order. The hearing order will set..., and other authorities; (3) The issues to be decided; (4) Such rules of procedure as may be necessary...
Procedures of Operation at Cranbrook Central Library.
ERIC Educational Resources Information Center
Cranbrook Institutions, Bloomfield Hills, MI. Central Library.
This manual outlines the ordering, cataloging and classification, and processing procedures for books, periodicals, government documents, and non-book materials for a central library serving three schools--a co-ed elementary school and separate junior-senior high schools for boys and girls--and four special libraries--a fine and rare books…
14 CFR 13.226 - Public disclosure of evidence.
Code of Federal Regulations, 2011 CFR
2011-01-01
... PROCEDURAL RULES INVESTIGATIVE AND ENFORCEMENT PROCEDURES Rules of Practice in FAA Civil Penalty Actions § 13... information in the record by filing a written motion to withhold specific information with the administrative law judge and serving a copy of the motion on each party. The party shall state the specific grounds...
14 CFR 13.226 - Public disclosure of evidence.
Code of Federal Regulations, 2010 CFR
2010-01-01
... PROCEDURAL RULES INVESTIGATIVE AND ENFORCEMENT PROCEDURES Rules of Practice in FAA Civil Penalty Actions § 13... information in the record by filing a written motion to withhold specific information with the administrative law judge and serving a copy of the motion on each party. The party shall state the specific grounds...
5 CFR 1201.111 - Initial decision by judge.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Initial decision by judge. 1201.111... PRACTICES AND PROCEDURES Procedures for Appellate Cases Final Decisions § 1201.111 Initial decision by judge. (a) The judge will prepare an initial decision after the record closes, and will serve that decision...
Code of Federal Regulations, 2010 CFR
2010-07-01
... chooses to use the cohort approach in its project, serve under the program's early intervention component... cohort approach in its project, serve under the program's early intervention component? A Partnership, or a State that chooses to use a cohort approach in its GEAR UP early intervention component, must...
Code of Federal Regulations, 2013 CFR
2013-07-01
... chooses to use the cohort approach in its project, serve under the program's early intervention component... chooses to use the cohort approach in its project, serve under the program's early intervention component? A Partnership, or a State that chooses to use a cohort approach in its GEAR UP early intervention...
Code of Federal Regulations, 2012 CFR
2012-07-01
... chooses to use the cohort approach in its project, serve under the program's early intervention component... chooses to use the cohort approach in its project, serve under the program's early intervention component? A Partnership, or a State that chooses to use a cohort approach in its GEAR UP early intervention...
Code of Federal Regulations, 2014 CFR
2014-07-01
... chooses to use the cohort approach in its project, serve under the program's early intervention component... chooses to use the cohort approach in its project, serve under the program's early intervention component? A Partnership, or a State that chooses to use a cohort approach in its GEAR UP early intervention...
Code of Federal Regulations, 2011 CFR
2011-07-01
... chooses to use the cohort approach in its project, serve under the program's early intervention component... chooses to use the cohort approach in its project, serve under the program's early intervention component? A Partnership, or a State that chooses to use a cohort approach in its GEAR UP early intervention...
Aftershock identification problem via the nearest-neighbor analysis for marked point processes
NASA Astrophysics Data System (ADS)
Gabrielov, A.; Zaliapin, I.; Wong, H.; Keilis-Borok, V.
2007-12-01
The centennial observations on the world seismicity have revealed a wide variety of clustering phenomena that unfold in the space-time-energy domain and provide most reliable information about the earthquake dynamics. However, there is neither a unifying theory nor a convenient statistical apparatus that would naturally account for the different types of seismic clustering. In this talk we present a theoretical framework for nearest-neighbor analysis of marked processes and obtain new results on hierarchical approach to studying seismic clustering introduced by Baiesi and Paczuski (2004). Recall that under this approach one defines an asymmetric distance D in space-time-energy domain such that the nearest-neighbor spanning graph with respect to D becomes a time- oriented tree. We demonstrate how this approach can be used to detect earthquake clustering. We apply our analysis to the observed seismicity of California and synthetic catalogs from ETAS model and show that the earthquake clustering part is statistically different from the homogeneous part. This finding may serve as a basis for an objective aftershock identification procedure.
5 CFR 297.402 - Disclosure pursuant to a compulsory legal process served on the Office.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Disclosure pursuant to a compulsory legal process served on the Office. 297.402 Section 297.402 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PRIVACY PROCEDURES FOR PERSONNEL RECORDS Disclosure of Records § 297.402 Disclosure pursuant to a compulsory...
12 CFR 908.26 - Service of papers.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 12 Banks and Banking 7 2011-01-01 2011-01-01 false Service of papers. 908.26 Section 908.26 Banks... RULES OF PRACTICE AND PROCEDURE IN HEARINGS ON THE RECORD General Rules § 908.26 Service of papers. (a) By the parties. Except as otherwise provided, a party filing papers or serving a subpoena shall serve...
12 CFR 908.26 - Service of papers.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Service of papers. 908.26 Section 908.26 Banks... RULES OF PRACTICE AND PROCEDURE IN HEARINGS ON THE RECORD General Rules § 908.26 Service of papers. (a) By the parties. Except as otherwise provided, a party filing papers or serving a subpoena shall serve...
Emerging applications of nanoparticles for lung cancer diagnosis and therapy
NASA Astrophysics Data System (ADS)
Sukumar, Uday Kumar; Bhushan, Bharat; Dubey, Poornima; Matai, Ishita; Sachdev, Abhay; Packirisamy, Gopinath
2013-07-01
Lung cancer is by far the leading cause of cancer-related mortality worldwide, most of them being active tobacco smokers. Non small cell lung cancer accounts for around 85% to 90% of deaths, whereas the rest is contributed by small cell lung cancer. The extreme lethality of lung cancer arises due to lack of suitable diagnostic procedures for early detection of lung cancer and ineffective conventional therapeutic strategies. In course with desperate attempts to address these issues independently, a multifunctional nanotherapeutic or diagnostic system is being sought as a favorable solution. The manifestation of physiochemical properties of such nanoscale systems is tuned favorably to come up with a versatile cancer cell targeted diagnostic and therapeutic system. Apart from this, the aspect of being at nanoscale by itself confers the system with an advantage of passive accumulation at the site of tumor. This review provides a broad perspective of three major subclasses of such nanoscale therapeutic and diagnostic systems which include polymeric nanoparticles-based approaches, metal nanoparticles-based approaches, and bio-nanoparticles-based approaches. This review work also serves the purpose of gaining an insight into the pros and cons of each of these approaches with a prospective improvement in lung cancer therapeutics and diagnostics.
Whitmore, Henschke, and Hilaris: The reorientation of prostate brachytherapy (1970-1987).
Aronowitz, Jesse N
2012-01-01
Urologists had performed prostate brachytherapy for decades before New York's Memorial Hospital retropubic program. This paper explores the contribution of Willet Whitmore, Ulrich Henschke, Basil Hilaris, and Memorial's physicists to the evolution of the procedure. Literature review and interviews with program participants. More than 1000 retropubic implants were performed at Memorial between 1970 and 1987. Unlike previous efforts, Memorial's program benefited from the participation of three disciplines in its conception and execution. Memorial's retropubic program was a collaboration of urologists, radiation therapists, and physicists. Their approach focused greater attention on dosimetry and radiation safety, and served as a template for subsequent prostate brachytherapy programs. Copyright © 2012 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.
A quantitative witness for Greenberger-Horne-Zeilinger entanglement.
Eltschka, Christopher; Siewert, Jens
2012-01-01
Along with the vast progress in experimental quantum technologies there is an increasing demand for the quantification of entanglement between three or more quantum systems. Theory still does not provide adequate tools for this purpose. The objective is, besides the quest for exact results, to develop operational methods that allow for efficient entanglement quantification. Here we put forward an analytical approach that serves both these goals. We provide a simple procedure to quantify Greenberger-Horne-Zeilinger-type multipartite entanglement in arbitrary three-qubit states. For two qubits this method is equivalent to Wootters' seminal result for the concurrence. It establishes a close link between entanglement quantification and entanglement detection by witnesses, and can be generalised both to higher dimensions and to more than three parties.
Imaging of dynamic ion signaling during root gravitropism.
Monshausen, Gabriele B
2015-01-01
Gravitropic signaling is a complex process that requires the coordinated action of multiple cell types and tissues. Ca(2+) and pH signaling are key components of gravitropic signaling cascades and can serve as useful markers to dissect the molecular machinery mediating plant gravitropism. To monitor dynamic ion signaling, imaging approaches combining fluorescent ion sensors and confocal fluorescence microscopy are employed, which allow the visualization of pH and Ca(2+) changes at the level of entire tissues, while also providing high spatiotemporal resolution. Here, I describe procedures to prepare Arabidopsis seedlings for live cell imaging and to convert a microscope for vertical stage fluorescence microscopy. With this imaging system, ion signaling can be monitored during all phases of the root gravitropic response.
Surface-water quality-assurance plan for the U.S. Geological Survey Washington Water Science Center
Mastin, Mark C.
2016-02-19
This Surface-Water Quality-Assurance Plan documents the standards, policies, and procedures used by the U.S. Geological Survey Washington Water Science Center (WAWSC) for activities related to the collection, processing, storage, analysis, and publication of surface-water data. This plan serves as a guide to all WAWSC personnel involved in surface-water data activities, and changes as the needs and requirements of the WAWSC change. Regular updates to this plan represent an integral part of the quality-assurance process. In the WAWSC, direct oversight and responsibility by the hydrographer(s) assigned to a surface-water station, combined with team approaches in all work efforts, assure highquality data, analyses, reviews, and reports for cooperating agencies and the public.
Polyadenylation state microarray (PASTA) analysis.
Beilharz, Traude H; Preiss, Thomas
2011-01-01
Nearly all eukaryotic mRNAs terminate in a poly(A) tail that serves important roles in mRNA utilization. In the cytoplasm, the poly(A) tail promotes both mRNA stability and translation, and these functions are frequently regulated through changes in tail length. To identify the scope of poly(A) tail length control in a transcriptome, we developed the polyadenylation state microarray (PASTA) method. It involves the purification of mRNA based on poly(A) tail length using thermal elution from poly(U) sepharose, followed by microarray analysis of the resulting fractions. In this chapter we detail our PASTA approach and describe some methods for bulk and mRNA-specific poly(A) tail length measurements of use to monitor the procedure and independently verify the microarray data.
A quantitative witness for Greenberger-Horne-Zeilinger entanglement
Eltschka, Christopher; Siewert, Jens
2012-01-01
Along with the vast progress in experimental quantum technologies there is an increasing demand for the quantification of entanglement between three or more quantum systems. Theory still does not provide adequate tools for this purpose. The objective is, besides the quest for exact results, to develop operational methods that allow for efficient entanglement quantification. Here we put forward an analytical approach that serves both these goals. We provide a simple procedure to quantify Greenberger-Horne-Zeilinger–type multipartite entanglement in arbitrary three-qubit states. For two qubits this method is equivalent to Wootters' seminal result for the concurrence. It establishes a close link between entanglement quantification and entanglement detection by witnesses, and can be generalised both to higher dimensions and to more than three parties. PMID:23267431
The impact of health care provider market served on health care channel relationships.
Smith, M F; Pirog, S F
1990-01-01
A conceptual framework is provided in which manufacturer-wholesaler relationships are addressed in the context of the health care provider segment served by the wholesaler. A study of the medical supply channel demonstrates how the particular market served by the wholesaler shapes the manufacturer-wholesaler relationship along the behavioral dimensions of manifest conflict, coercion, satisfaction and openness of communications. The health care provider segment served was found to have a significant impact on these dimensions. The results of this research suggest that channel member strategies, policies and operating procedures must account for variations in input (supply) and output (market) environments.
Wang, Chun-Neng; Hsu, Hao-Chun; Wang, Cheng-Chun; Lee, Tzu-Kuei; Kuo, Yan-Fu
2015-01-01
The quantification of floral shape variations is difficult because flower structures are both diverse and complex. Traditionally, floral shape variations are quantified using the qualitative and linear measurements of two-dimensional (2D) images. The 2D images cannot adequately describe flower structures, and thus lead to unsatisfactory discrimination of the flower shape. This study aimed to acquire three-dimensional (3D) images by using microcomputed tomography (μCT) and to examine the floral shape variations by using geometric morphometrics (GM). To demonstrate the advantages of the 3D-μCT-GM approach, we applied the approach to a second-generation population of florist's gloxinia (Sinningia speciosa) crossed from parents of zygomorphic and actinomorphic flowers. The flowers in the population considerably vary in size and shape, thereby served as good materials to test the applicability of the proposed phenotyping approach. Procedures were developed to acquire 3D volumetric flower images using a μCT scanner, to segment the flower regions from the background, and to select homologous characteristic points (i.e., landmarks) from the flower images for the subsequent GM analysis. The procedures identified 95 landmarks for each flower and thus improved the capability of describing and illustrating the flower shapes, compared with typically lower number of landmarks in 2D analyses. The GM analysis demonstrated that flower opening and dorsoventral symmetry were the principal shape variations of the flowers. The degrees of flower opening and corolla asymmetry were then subsequently quantified directly from the 3D flower images. The 3D-μCT-GM approach revealed shape variations that could not be identified using typical 2D approaches and accurately quantified the flower traits that presented a challenge in 2D images. The approach opens new avenues to investigate floral shape variations.
13 CFR 121.1103 - What are the procedures for appealing a NAICS code designation?
Code of Federal Regulations, 2010 CFR
2010-01-01
... appealing a NAICS code designation? 121.1103 Section 121.1103 Business Credit and Assistance SMALL BUSINESS... Determinations and Naics Code Designations § 121.1103 What are the procedures for appealing a NAICS code... code designation and applicable size standard must be served and filed within 10 calendar days after...
29 CFR 417.6 - Powers of Administrative Law Judge.
Code of Federal Regulations, 2014 CFR
2014-07-01
... whenever the ends of justice would be served thereby; (f) To regulate the course of the hearing; (g) To... dispose of procedural requests or other matters; (i) To limit the number of witnesses at hearings, or... reschedule hearings for good cause shown; (l) To consider and decide procedural matters; (m) To take any...
29 CFR 417.6 - Powers of Administrative Law Judge.
Code of Federal Regulations, 2011 CFR
2011-07-01
... whenever the ends of justice would be served thereby; (f) To regulate the course of the hearing; (g) To... dispose of procedural requests or other matters; (i) To limit the number of witnesses at hearings, or... reschedule hearings for good cause shown; (l) To consider and decide procedural matters; (m) To take any...
29 CFR 417.6 - Powers of Administrative Law Judge.
Code of Federal Regulations, 2012 CFR
2012-07-01
... whenever the ends of justice would be served thereby; (f) To regulate the course of the hearing; (g) To... dispose of procedural requests or other matters; (i) To limit the number of witnesses at hearings, or... reschedule hearings for good cause shown; (l) To consider and decide procedural matters; (m) To take any...
29 CFR 417.6 - Powers of Administrative Law Judge.
Code of Federal Regulations, 2013 CFR
2013-07-01
... whenever the ends of justice would be served thereby; (f) To regulate the course of the hearing; (g) To... dispose of procedural requests or other matters; (i) To limit the number of witnesses at hearings, or... reschedule hearings for good cause shown; (l) To consider and decide procedural matters; (m) To take any...
TESTING AND EVALUATION IN THE BIOLOGICAL SCIENCES.
ERIC Educational Resources Information Center
NELSON, CLARENCE H.
THIS REPORT OF THE CUEBS PANEL ON EDUCATION AND TESTING SERVES AS A RESOURCE FOR THE INSTRUCTOR PREPARING COURSE EXAMINATIONS. THE MAJOR TOPICS DISCUSSED ARE (1) THE PROCEDURES IN PREPARING AN ACHIEVEMENT TEST, (2) THE CATEGORIZATION AND CODING OF TEST ITEMS, AND (3) THE ADVANTAGES AND LIMITATIONS OF VARIOUS TESTING PROCEDURES. OVER 1300 OBJECTIVE…
20 CFR 802.304 - Purpose of oral argument.
Code of Federal Regulations, 2010 CFR
2010-04-01
....304 Employees' Benefits BENEFITS REVIEW BOARD, DEPARTMENT OF LABOR RULES OF PRACTICE AND PROCEDURE Procedure for Review Oral Argument Before the Board § 802.304 Purpose of oral argument. Oral argument may be...; or (b) When in the interests of justice oral argument will serve to assist the Board in carrying out...
Introducing Statistical Inference to Biology Students through Bootstrapping and Randomization
ERIC Educational Resources Information Center
Lock, Robin H.; Lock, Patti Frazer
2008-01-01
Bootstrap methods and randomization tests are increasingly being used as alternatives to standard statistical procedures in biology. They also serve as an effective introduction to the key ideas of statistical inference in introductory courses for biology students. We discuss the use of such simulation based procedures in an integrated curriculum…
Oregon Graduation Requirements: Guidelines for Record Keeping Procedures and Sample Forms.
ERIC Educational Resources Information Center
Oregon State Dept. of Education, Salem.
These guidelines and sample forms for record keeping are intended to serve as a supplement to Oregon Graduation Requirements, Administrative Guidelines (Section 1), which was published in September 1973. The purposes of the guidelines and sample forms are to outline various record-keeping procedures and to provide sample forms that districts may…
ERIC Educational Resources Information Center
Adamson, Martin; And Others
Intended for use by curriculum committees or individuals charged with responsibility for the selection of provincially authorized learning resources, this document contains guidelines and procedures intended to serve as minimum standard requirements for the provincial evaluation and selection of learning resources. Learning resources are defined…
Scoring procedures were developed to convert a respondent's screener responses to estimates of individual dietary intake for percentage energy from fat, grams of fiber, and servings of fruits and vegetables, using USDA's 1994-96 Continuing Survey of Food Intakes of Individuals (CSFII 94-96) dietary recall data.
Documentation for the 2003-04 Schools and Staffing Survey. NCES 2007-337
ERIC Educational Resources Information Center
Tourkin, Steven C.; Warner, Toni; Parmer, Randall; Cole, Cornette; Jackson, Betty; Zukerberg, Andrew; Cox, Shawna; Soderberg, Andrew
2007-01-01
This report serves as the survey documentation for the design and implementation of the 2003-04 Schools and Staffing Survey. Topics covered include the sample design, survey methodology, data collection procedures, data processing, response rates, imputation procedures, weighting and variance estimation, review of the quality of data, the types of…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-19
... proposed to support the Charlotte Optimization of Airspace and Procedures in a Metroplex (OAPM) project.... 11-2A, Notice of Proposed Rulemaking Distribution System, which describes the application procedure... corridors serving the Charlotte area and would enhance the efficiency of the National Airspace System in the...
32 CFR 156.4 - Responsibilities.
Code of Federal Regulations, 2014 CFR
2014-07-01
..., training, and awareness support to the DoD PSP. (5) Serve as the primary contact between DoD, the Red Cross... for contracts and agreements that require non-DoD personnel to adhere to personnel security procedures... administrative due process procedures of the DoD PSP. (2) Perform functions relating to the DoD PSP including the...
15 CFR 904.206 - Pleadings, motions, and service.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Pleadings, motions, and service. 904... PROCEDURES Hearing and Appeal Procedures General § 904.206 Pleadings, motions, and service. (a) The original of all pleadings and documents must be filed with the Judge and a copy served upon the ALJ Docketing...
ERIC Educational Resources Information Center
Library of Congress, Washington, DC. National Library Service for the Blind and Physically Handicapped.
Using a question and answer format, this report provides answers to a wide variety of questions and requests about National Library Service policies and procedures, planning and development, reading materials, equipment, and publication services of concern to librarians serving these user groups. Questions directed to guest speakers and panelists…
ERIC Educational Resources Information Center
Saul, Janet; Audage, Natalie C.
2007-01-01
Youth-serving organizations strive to create a safe environment for youth, employees, and volunteers so that youth can grow, learn, and have fun. Part of creating a safe environment is making sure that youth are not harmed in any way while participating in organization-sponsored activities. One risk in any organization working directly with youth…
NASA Astrophysics Data System (ADS)
Steelman, Toddi A.; Dumond, Melissa Elefante
2009-03-01
In the United States, the common interest often is conceived as a by-product of the pluralist, interest-group-driven democratic process. Special interests dominate in many political arenas. Consequently, we have lost the language, vocabulary, and ability to talk about the common interest. The way to reverse this trend is to develop and practice with new tools that allow us to articulate what we mean by the common interest in specific contexts. In this article, we leveraged the literature on procedural, substantive, and pragmatic decision making to illustrate how they work together to demonstrate whether and how the common interest was served in three case studies of Healthy Forests Restoration Act implementation on the Apache-Sitgreaves National Forest in Arizona. In two of the cases we found that the common interest was mostly served, while in the third case it was not. Our results raise questions about the ability of procedural criteria or substantive criteria alone to determine effectiveness in decision making. When evaluated together they provide a more complete understanding of how the common interest is or is not served.
Evaluation of environmental aspects significance in ISO 14001.
Põder, Tõnis
2006-05-01
The methodological framework set by standards ISO 14001 and ISO 14004 gives only general principles for environmental aspects assessment, which is regarded as one of the most critical stages of implementing environmental management system. In Estonia, about 100 organizations have been certified to the ISO 14001. Experience obtained from numerous companies has demonstrated that limited transparency and reproducibility of the assessment process serves as a common shortcoming. Despite rather complicated assessment schemes sometimes used, the evaluation procedures have been largely based on subjective judgments because of ill-defined and inadequate assessment criteria. A comparison with some similar studies in other countries indicates a general nature of observed inconsistencies. The diversity of approaches to the aspects' assessment in concept literature and to the related problems has been discussed. The general structure of basic assessment criteria, compatible with environmental impact assessment and environmental risk analysis has also been outlined. Based on this general structure, the article presents a tiered approach to help organize the assessment in a more consistent manner.
Schencking, Martin; Sönnichsen, Andreas; Bassüner, Susanne; Redaelli, Marcus
2015-01-01
There is limited valid data available on CAM procedures for chronic joint and neuropathic pain in primary care in Germany. Indiviual CAM qualifications of the general practitioners (GPs) and the potential of cost reduction through CAM treatment are almost unknown. The aim of this pilot trial preceding the main study is to examine the survey mode, to estimate the response rate by GPs with or without an additional qualification for CAM, and to identify the status quo in therapeutic approaches for chronic pain disorders in primary care. This is a cross-sectional study with an ex post facto design among German GPs consisting of 2 parts: In a first step, a pilot trial precedes the main study targeting 200 GPs with and 200 GPs without additional qualification in CAM in a selected region. The results of the CUPCIG study comprise the distribution of pain types treated in primary care practices, the GPs' attitude toward complementary pain therapy, pharmacological or CAM treatment, the estimate of cost reduction through CAM treatment of pain, the application of diverse CAM procedures, and biographical data. The CUPCIG study serves to compile pain therapy approaches in primary care in Germany with respect to the individual CAM expertise of the GPs. © 2015 S. Karger GmbH, Freiburg.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Trément, Sébastien; Rousseau, Bernard, E-mail: bernard.rousseau@u-psud.fr; Schnell, Benoît
2014-04-07
We apply operational procedures available in the literature to the construction of coarse-grained conservative and friction forces for use in dissipative particle dynamics (DPD) simulations. The full procedure rely on a bottom-up approach: large molecular dynamics trajectories of n-pentane and n-decane modeled with an anisotropic united atom model serve as input for the force field generation. As a consequence, the coarse-grained model is expected to reproduce at least semi-quantitatively structural and dynamical properties of the underlying atomistic model. Two different coarse-graining levels are studied, corresponding to five and ten carbon atoms per DPD bead. The influence of the coarse-graining levelmore » on the generated force fields contributions, namely, the conservative and the friction part, is discussed. It is shown that the coarse-grained model of n-pentane correctly reproduces self-diffusion and viscosity coefficients of real n-pentane, while the fully coarse-grained model for n-decane at ambient temperature over-predicts diffusion by a factor of 2. However, when the n-pentane coarse-grained model is used as a building block for larger molecule (e.g., n-decane as a two blobs model), a much better agreement with experimental data is obtained, suggesting that the force field constructed is transferable to large macro-molecular systems.« less
Analytical approximations to the dynamics of an array of coupled DC SQUIDs
NASA Astrophysics Data System (ADS)
Berggren, Susan; Palacios, Antonio
2014-04-01
Coupled dynamical systems that operate near the onset of a bifurcation can lead, under certain conditions, to strong signal amplification effects. Over the past years we have studied this generic feature on a wide range of systems, including: magnetic and electric fields sensors, gyroscopic devices, and arrays of loops of superconducting quantum interference devices, also known as SQUIDs. In this work, we consider an array of SQUID loops connected in series as a case study to derive asymptotic analytical approximations to the exact solutions through perturbation analysis. Two approaches are considered. First, a straightforward expansion in which the non-linear parameter related to the inductance of the DC SQUID is treated as the small perturbation parameter. Second, a more accurate procedure that considers the SQUID phase dynamics as non-uniform motion on a circle. This second procedure is readily extended to the series array and it could serve as a mathematical framework to find approximate solutions to related complex systems with high-dimensionality. To the best of our knowledge, an approximate analytical solutions to an array of SQUIDs has not been reported yet in the literature.
Miller, P L; Frawley, S J; Sayward, F G; Yasnoff, W A; Duncan, L; Fleming, D W
1997-06-01
IMM/Serve is a computer program which implements the clinical guidelines for childhood immunization. IMM/Serve accepts as input a child's immunization history. It then indicates which vaccinations are due and which vaccinations should be scheduled next. The clinical guidelines for immunization are quite complex and are modified quite frequently. As a result, it is important that IMM/Serve's knowledge be represented in a format that facilitates the maintenance of that knowledge as the field evolves over time. To achieve this goal, IMM/Serve uses four representations for different parts of its knowledge base: (1) Immunization forecasting parameters that specify the minimum ages and wait-intervals for each dose are stored in tabular form. (2) The clinical logic that determines which set of forecasting parameters applies for a particular patient in each vaccine series is represented using if-then rules. (3) The temporal logic that combines dates, ages, and intervals to calculate recommended dates, is expressed procedurally. (4) The screening logic that checks each previous dose for validity is performed using a decision table that combines minimum ages and wait intervals with a small amount of clinical logic. A knowledge maintenance tool, IMM/Def, has been developed to help maintain the rule-based logic. The paper describes the design of IMM/Serve and the rationale and role of the different forms of knowledge used.
NASA Astrophysics Data System (ADS)
Mccann, A. R.; Cardace, D.; Carnevale, D.
2011-12-01
The role of technology is an increasingly important resource in preparing students for the future. The Internet is a widely accessible tool. Technology has also made us more connected, allowing constant communication and instantaneous data sharing. Public utilities such as those found on the web, including blogs, are a means to convey scientific research in rapid, useful ways. This tool is ideal for newly emerging fields, allowing up-to-date collaboration and referencing of ongoing studies, as well as bringing students virtually into the field or laboratory through videos, pictures, and records of project work. Astrobiology is a high interest topic, integrating geology, chemistry, biology, and physics. Terrestrial Mars analog environments are compelling in that they shed light on unusual opportunities for diverse life in settings beyond Earth. For this study, the analog site locality is at the University of California-Davis McLaughlin Natural Reserve in the Coast Range Ophiolite, a portion of actively serpentinizing, uplifted oceanic material in northern California (see companion poster, McCann et al., Mineralogy of Surface Serpentinite Outcrops in the Coast Range Ophiolite: Implications for the Deep Biosphere and Astrobiology). Our research objective is to monitor the activity taking place within the subsurface biosphere through an interdisciplinary approach involving biogeochemists, microbiologists, organic geochemists, and geologists. The study of serpentinization with astrobiological ground-truthing is a relatively new and promising field. Scientific field procedures are constantly being modified as they are applied. In order to better collaborate study efforts, a daily field journal is being written, recording ideas, discussions, procedures, problems, solutions, and results. It serves as an informal report, including pictures and video clips of the field activity. The journal is maintained as an online blog for ease of use and accessibility, as well as public comment. Its secondary purpose is to serve as a resource oriented toward high school science classrooms interested in cutting edge scientific endeavors. Included are video interviews of each participating scientist, covering topics such as professional background, past studies, their parts in the ongoing project and what they hope to gain through this research. By piecing together the various scientific approaches with the procedural field work, I am simplifying the massive amount of details involved between proposing a project and having a presentable result. As a high school student, the enormity of research possibilities can be in awe-inspiring contrast with the precision of the end result. This blog is interlocking the important components of our field campaign so that the audience will understand better the tasks involved in the field of scientific research. It not only will bring clarity and realism to the scientific process, but will serve to convey the passion and life involved in the research by the people that love what they do.
Development of a robust space power system decision model
NASA Astrophysics Data System (ADS)
Chew, Gilbert; Pelaccio, Dennis G.; Jacobs, Mark; Stancati, Michael; Cataldo, Robert
2001-02-01
NASA continues to evaluate power systems to support human exploration of the Moon and Mars. The system(s) would address all power needs of surface bases and on-board power for space transfer vehicles. Prior studies have examined both solar and nuclear-based alternatives with respect to individual issues such as sizing or cost. What has not been addressed is a comprehensive look at the risks and benefits of the options that could serve as the analytical framework to support a system choice that best serves the needs of the exploration program. This paper describes the SAIC developed Space Power System Decision Model, which uses a formal Two-step Analytical Hierarchy Process (TAHP) methodology that is used in the decision-making process to clearly distinguish candidate power systems in terms of benefits, safety, and risk. TAHP is a decision making process based on the Analytical Hierarchy Process, which employs a hierarchic approach of structuring decision factors by weights, and relatively ranks system design options on a consistent basis. This decision process also includes a level of data gathering and organization that produces a consistent, well-documented assessment, from which the capability of each power system option to meet top-level goals can be prioritized. The model defined on this effort focuses on the comparative assessment candidate power system options for Mars surface application(s). This paper describes the principles of this approach, the assessment criteria and weighting procedures, and the tools to capture and assess the expert knowledge associated with space power system evaluation. .
NASA Astrophysics Data System (ADS)
Perruchoud, David; Pisotta, Iolanda; Carda, Stefano; Murray, Micah M.; Ionta, Silvio
2016-08-01
Objective. Brain-machine interfaces (BMIs) re-establish communication channels between the nervous system and an external device. The use of BMI technology has generated significant developments in rehabilitative medicine, promising new ways to restore lost sensory-motor functions. However and despite high-caliber basic research, only a few prototypes have successfully left the laboratory and are currently home-deployed. Approach. The failure of this laboratory-to-user transfer likely relates to the absence of BMI solutions for providing naturalistic feedback about the consequences of the BMI’s actions. To overcome this limitation, nowadays cutting-edge BMI advances are guided by the principle of biomimicry; i.e. the artificial reproduction of normal neural mechanisms. Main results. Here, we focus on the importance of somatosensory feedback in BMIs devoted to reproducing movements with the goal of serving as a reference framework for future research on innovative rehabilitation procedures. First, we address the correspondence between users’ needs and BMI solutions. Then, we describe the main features of invasive and non-invasive BMIs, including their degree of biomimicry and respective advantages and drawbacks. Furthermore, we explore the prevalent approaches for providing quasi-natural sensory feedback in BMI settings. Finally, we cover special situations that can promote biomimicry and we present the future directions in basic research and clinical applications. Significance. The continued incorporation of biomimetic features into the design of BMIs will surely serve to further ameliorate the realism of BMIs, as well as tremendously improve their actuation, acceptance, and use.
NASA Astrophysics Data System (ADS)
Prideaux, Brendan; Atkinson, Sally J.; Carolan, Vikki A.; Morton, Jacqueline; Clench, Malcolm R.
2007-02-01
Aspects of the indirect examination of xenobiotic distribution on the surface of and within skin sections by imaging matrix assisted laser desorption ionisation mass spectrometry (MALDI-MS) have been examined. A solvent assisted blotting technique previously developed for the examination of the absorption of agrochemicals into leaves has been examined for the analysis of the distribution of hydrocortisone on the surface of skin. It was found that by careful control of the extraction and blotting procedure an 80-fold sensitivity improvement could by obtained over dry blotting with only 10% lateral diffusion of the image. However, in contrast it was found that the use of a hydrophobic blotting membrane was more suitable for the examination of the transdermal absorption of the pesticide chlorpyrifos. The potential of incorporating a derivatisation step into the solvent assisted blotting procedure was investigated by blotting isocyanate treated skin onto a methanol soaked blotting membrane. This served the dual purpose of derivatising the isocyanate to a stable substituted urea derivative and extracting it from the skin. Preliminary data indicate that this approach may have some merit for field sampling for such compound and clearly derivatisation also offers the potential for sensitivity enhancements. Finally, the use of principal components analysis with an ion species specific normalisation procedure is proposed to identify regions of drug treated skin where the ion abundance of the compound of interest is low.
Huang, Erich P; Wang, Xiao-Feng; Choudhury, Kingshuk Roy; McShane, Lisa M; Gönen, Mithat; Ye, Jingjing; Buckler, Andrew J; Kinahan, Paul E; Reeves, Anthony P; Jackson, Edward F; Guimaraes, Alexander R; Zahlmann, Gudrun
2015-02-01
Medical imaging serves many roles in patient care and the drug approval process, including assessing treatment response and guiding treatment decisions. These roles often involve a quantitative imaging biomarker, an objectively measured characteristic of the underlying anatomic structure or biochemical process derived from medical images. Before a quantitative imaging biomarker is accepted for use in such roles, the imaging procedure to acquire it must undergo evaluation of its technical performance, which entails assessment of performance metrics such as repeatability and reproducibility of the quantitative imaging biomarker. Ideally, this evaluation will involve quantitative summaries of results from multiple studies to overcome limitations due to the typically small sample sizes of technical performance studies and/or to include a broader range of clinical settings and patient populations. This paper is a review of meta-analysis procedures for such an evaluation, including identification of suitable studies, statistical methodology to evaluate and summarize the performance metrics, and complete and transparent reporting of the results. This review addresses challenges typical of meta-analyses of technical performance, particularly small study sizes, which often causes violations of assumptions underlying standard meta-analysis techniques. Alternative approaches to address these difficulties are also presented; simulation studies indicate that they outperform standard techniques when some studies are small. The meta-analysis procedures presented are also applied to actual [18F]-fluorodeoxyglucose positron emission tomography (FDG-PET) test-retest repeatability data for illustrative purposes. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.
Huang, Erich P; Wang, Xiao-Feng; Choudhury, Kingshuk Roy; McShane, Lisa M; Gönen, Mithat; Ye, Jingjing; Buckler, Andrew J; Kinahan, Paul E; Reeves, Anthony P; Jackson, Edward F; Guimaraes, Alexander R; Zahlmann, Gudrun
2017-01-01
Medical imaging serves many roles in patient care and the drug approval process, including assessing treatment response and guiding treatment decisions. These roles often involve a quantitative imaging biomarker, an objectively measured characteristic of the underlying anatomic structure or biochemical process derived from medical images. Before a quantitative imaging biomarker is accepted for use in such roles, the imaging procedure to acquire it must undergo evaluation of its technical performance, which entails assessment of performance metrics such as repeatability and reproducibility of the quantitative imaging biomarker. Ideally, this evaluation will involve quantitative summaries of results from multiple studies to overcome limitations due to the typically small sample sizes of technical performance studies and/or to include a broader range of clinical settings and patient populations. This paper is a review of meta-analysis procedures for such an evaluation, including identification of suitable studies, statistical methodology to evaluate and summarize the performance metrics, and complete and transparent reporting of the results. This review addresses challenges typical of meta-analyses of technical performance, particularly small study sizes, which often causes violations of assumptions underlying standard meta-analysis techniques. Alternative approaches to address these difficulties are also presented; simulation studies indicate that they outperform standard techniques when some studies are small. The meta-analysis procedures presented are also applied to actual [18F]-fluorodeoxyglucose positron emission tomography (FDG-PET) test–retest repeatability data for illustrative purposes. PMID:24872353
ERIC Educational Resources Information Center
Humphreys, Michael S.; And Others
1989-01-01
An associative theory of memory is proposed to serve as a counterexample to claims that dissociations among episodic, semantic, and procedural memory tasks necessitate separate memory systems. The theory is based on task analyses of matching (recognition and familiarity judgments), retrieval (cued recall), and production (free association). (TJH)
ERIC Educational Resources Information Center
Kangas, Brian D.; Branch, Marc N.
2012-01-01
The effects of cocaine were examined under a titrating-delay matching-to-sample procedure. In this procedure, the delay between sample stimulus offset and comparison stimuli onset adjusts as a function of the subject's performance. Specifically, matches increase the delay and mismatches decrease the delay. Titrated delay values served as the…
Ramapo College of New Jersey Handbook for Professional Staff, 1975-1976.
ERIC Educational Resources Information Center
Ramapo Coll. of New Jersey, Mahwah.
While the faculty handbook of Ramapo College is not intended to give complete and detailed information about all of the college's policies and procedures, it is intended to serve as a guide to the administrative and academic regulations, procedures, and obligations as of 1975-76. Sections are: (1) organization and governance, containing general…
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Procedure when a demand is issued in a legal proceeding involving the United States. 1263.102 Section 1263.102 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION DEMAND FOR INFORMATION OR TESTIMONY SERVED ON AGENCY EMPLOYEES...
2016-12-16
We are revising our rules so that more of our procedures at the hearing and Appeals Council levels of our administrative review process are consistent nationwide. We anticipate that these nationally consistent procedures will enable us to administer our disability programs more efficiently and better serve the public.
12 CFR 308.11 - Service of papers.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 12 Banks and Banking 4 2011-01-01 2011-01-01 false Service of papers. 308.11 Section 308.11 Banks... AND PROCEDURE Uniform Rules of Practice and Procedure § 308.11 Service of papers. (a) By the parties. Except as otherwise provided, a party filing papers shall serve a copy upon the counsel of record for all...
12 CFR 308.11 - Service of papers.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Service of papers. 308.11 Section 308.11 Banks... AND PROCEDURE Uniform Rules of Practice and Procedure § 308.11 Service of papers. (a) By the parties. Except as otherwise provided, a party filing papers shall serve a copy upon the counsel of record for all...
17 CFR 201.151 - Filing of papers with the Commission: Procedure.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false Filing of papers with the... COMMISSION RULES OF PRACTICE Rules of Practice General Rules § 201.151 Filing of papers with the Commission: Procedure. (a) When to file. All papers required to be served by a party upon any person shall be filed...
NASA Astrophysics Data System (ADS)
Jurecka, Miroslawa; Niedzielski, Tomasz
2017-04-01
The objective of the approach presented in this paper is to demonstrate a potential of using the combination of two GIS-based models - mobility model and ring model - for delineating a region above which an Unmanned Aerial Vehicle (UAV) should fly to support the Search and Rescue (SAR) activities. The procedure is based on two concepts, both describing a possible distance/path that lost person could travel from the initial planning point (being either the point last seen, or point last known). The first approach (the ring model) takes into account the crow's flight distance traveled by a lost person and its probability distribution. The second concept (the mobility model) is based on the estimated travel speed and the associated features of the geographical environment of the search area. In contrast to the ring model covering global (hence more general) SAR perspective, the mobility model represents regional viewpoint by taking into consideration local impedance. Both models working together can serve well as a starting point for the UAV flight planning to strengthen the SAR procedures. We present the method of combining the two above-mentioned models in order to delineate UAVs flight region and increase the Probability of Success for future SAR missions. The procedure is a part of a larger Search and Rescue (SAR) system which is being developed at the University of Wrocław, Poland (research project no. IP2014 032773 financed by the Ministry of Science and Higher Education of Poland). The mobility and ring models have been applied to the Polish territory, and they act in concert to provide the UAV operator with the optimal search region. This is attained in real time so that the UAV-based SAR mission can be initiated quickly.
Lukanova, M; Miteva, I; Gorgioski, S; Popov, I
2008-01-01
To determine the trend in application of the basic therapeutical procedures in the most common gynaecological diseases combined or not with chronic pelvic pain /CPP/. In the prospective study conducted in the Gynaecological Clinic at the Department of Obstetrics and Gynaecology, MU-Pleven in the period 01.03.2004-01.07.2007, 1356 women with leiomyomatosis /L/, endometriosis /E/, adenomyosis /A/, pelvic congestion syndrome /PCS/, Allen-Masters syndrome /AMS/, pelvic inflammatory disease /PID/ and adhaesion syndrome /AS/, were included in it. They were grouped according to their age, type of disease, presence of CPP, type of therapeutical procedure and histological verification of the condition. For the purpose of the study the following methods were used: documentary method, R-AFS classification of E, inquiry method-by a questionnaire /form/, based on instruments for pain assessment, accepted worldwide. The highest frequency was determined for L, E and A, and AS. In the majority of the total number of consecutively admitted patients with those diseases an operative intervention was done, and almost one-sixth of women underwent conservative treatment. The same trend was observed in patients with chronic pain symptomatic, regarding their operative and conservative management. Histological verification of the condition was closely related with etiological reason and diagnostic approach. A balance between conservative and operative treatment should be set in the basis of therapeutical management, consistent with modern diagnostic procedures. Determination of the trend in treatment of women with CPP will lead to falling off of indiscriminate application of operative methods prior to exact diagnostic specification and setting of multidisciplinary approach. That will serve as a background for the future conduct to that group of patients.
ERIC Educational Resources Information Center
Caldwell, Stacy Lynette
2010-01-01
Students served in juvenile correctional school settings often arrive with histories of trauma, aversive educational experiences, low achievement, and other severe risk factors that impeded psychosocial development, educational progress, and occupational outcomes. Schools serving adjudicated youth must address a higher percentage of severe…
Trushkowsky, Richard; Arias, David Montalvo; David, Steven
Prior to initiating any treatment, it is necessary to visualize the desired outcomes. It then becomes possible to formulate the steps required to achieve this result. Digital Smile Design (DSD) utilizes patient input and information gathered through diagnostic procedures to create an esthetic treatment scheme. In the case presented here, the NYUCD Esthetic Evaluation Form, intraoral and extraoral photographs, mounted diagnostic casts, physical examination, and radiographs were the diagnostic modalities. The gathered information served as a starting point for a wax-up and intraoral mock-up. This case report demonstrates how the DSD served as a template for crown lengthening procedures and design of the final porcelain veneer restorations.
14 CFR Appendix A to Part 65 - Aircraft Dispatcher Courses
Code of Federal Regulations, 2014 CFR
2014-01-01
... school. For the latest technological advancements refer to the Practical Test Standards as published by.... Instrument Approach Procedures. (1) Transition Procedures. (2) Precision Approach Procedures. (3) Non-precision Approach Procedures. (4) Minimums and the relationship to weather. G. Special Navigation and...
14 CFR Appendix A to Part 65 - Aircraft Dispatcher Courses
Code of Federal Regulations, 2013 CFR
2013-01-01
... school. For the latest technological advancements refer to the Practical Test Standards as published by.... Instrument Approach Procedures. (1) Transition Procedures. (2) Precision Approach Procedures. (3) Non-precision Approach Procedures. (4) Minimums and the relationship to weather. G. Special Navigation and...
14 CFR Appendix A to Part 65 - Aircraft Dispatcher Courses
Code of Federal Regulations, 2010 CFR
2010-01-01
... school. For the latest technological advancements refer to the Practical Test Standards as published by.... Instrument Approach Procedures. (1) Transition Procedures. (2) Precision Approach Procedures. (3) Non-precision Approach Procedures. (4) Minimums and the relationship to weather. G. Special Navigation and...
14 CFR Appendix A to Part 65 - Aircraft Dispatcher Courses
Code of Federal Regulations, 2012 CFR
2012-01-01
... school. For the latest technological advancements refer to the Practical Test Standards as published by.... Instrument Approach Procedures. (1) Transition Procedures. (2) Precision Approach Procedures. (3) Non-precision Approach Procedures. (4) Minimums and the relationship to weather. G. Special Navigation and...
14 CFR Appendix A to Part 65 - Aircraft Dispatcher Courses
Code of Federal Regulations, 2011 CFR
2011-01-01
... school. For the latest technological advancements refer to the Practical Test Standards as published by.... Instrument Approach Procedures. (1) Transition Procedures. (2) Precision Approach Procedures. (3) Non-precision Approach Procedures. (4) Minimums and the relationship to weather. G. Special Navigation and...
Carbon Dioxide-Mediated C(sp3)-H Arylation of Amine Substrates.
Kapoor, Mohit; Liu, Daniel; Young, Michael C
2018-05-25
Elaborating amines via C-H functionalization has been an important area of research over the past decade but has generally relied on an added directing group or sterically hindered amine approach. Since free-amine-directed C(sp 3 )-H activation is still primarily limited to cyclization reactions and to improve the sustainability and reaction scope of amine-based C-H activation, we present a strategy using CO 2 in the form of dry ice that facilitates intermolecular C-H arylation. This methodology has been used to enable an operationally simple procedure whereby 1° and 2° aliphatic amines can be arylated selectively at their γ-C-H positions. In addition to potentially serving as a directing group, CO 2 has also been demonstrated to curtail the oxidation of sensitive amine substrates.
Wind-tunnel based definition of the AFE aerothermodynamic environment. [Aeroassist Flight Experiment
NASA Technical Reports Server (NTRS)
Miller, Charles G.; Wells, W. L.
1992-01-01
The Aeroassist Flight Experiment (AFE), scheduled to be performed in 1994, will serve as a precursor for aeroassisted space transfer vehicles (ASTV's) and is representative of entry concepts being considered for missions to Mars. Rationale for the AFE is reviewed briefly as are the various experiments carried aboard the vehicle. The approach used to determine hypersonic aerodynamic and aerothermodynamic characteristics over a wide range of simulation parameters in ground-based facilities is presented. Facilities, instrumentation and test procedures employed in the establishment of the data base are discussed. Measurements illustrating the effects of hypersonic simulation parameters, particularly normal-shock density ratio (an important parameter for hypersonic blunt bodies), and attitude on aerodynamic and aerothermodynamic characteristics are presented, and predictions from computational fluid dynamic (CFD) computer codes are compared with measurement.
Thoracostomy tubes: A comprehensive review of complications and related topics
Kwiatt, Michael; Tarbox, Abigail; Seamon, Mark J.; Swaroop, Mamta; Cipolla, James; Allen, Charles; Hallenbeck, Stacinoel; Davido, H. Tracy; Lindsey, David E.; Doraiswamy, Vijay A.; Galwankar, Sagar; Tulman, David; Latchana, Nicholas; Papadimos, Thomas J.; Cook, Charles H.; Stawicki, Stanislaw P.
2014-01-01
Tube thoracostomy (TT) placement belongs among the most commonly performed procedures. Despite many benefits of TT drainage, potential for significant morbidity and mortality exists. Abdominal or thoracic injury, fistula formation and vascular trauma are among the most serious, but more common complications such as recurrent pneumothorax, insertion site infection and nonfunctioning or malpositioned TT also represent a significant source of morbidity and treatment cost. Awareness of potential complications and familiarity with associated preventive, diagnostic and treatment strategies are fundamental to satisfactory patient outcomes. This review focuses on chest tube complications and related topics, with emphasis on prevention and problem-oriented approaches to diagnosis and treatment. The authors hope that this manuscript will serve as a valuable foundation for those who wish to become adept at the management of chest tubes. PMID:25024942
Surface-Water Quality-Assurance Plan for the Tallahassee Office, U.S. Geological Survey
Tomlinson, Stewart A.
2006-01-01
This Tallahassee Office Surface-Water Quality-Assurance Plan documents the standards, policies, and procedures used by the Tallahassee Office for activities related to the collection, processing, storage, analysis, and publication of surface-water data. This plan serves as a guide to all Tallahassee Office personnel involved in surface-water data activities, and changes as the needs and requirements of the Tallahassee Office, Florida Integrated Science Center, and Water Discipline change. Reg-ular updates to this Plan represent an integral part of the quality-assurance process. In the Tallahassee Office, direct oversight and responsibility by the employee(s) assigned to a surface-water station, combined with team approaches in all work efforts, assure high-quality data, analyses, reviews, and reports for cooperating agencies and the public.
An Enriched Shell Finite Element for Progressive Damage Simulation in Composite Laminates
NASA Technical Reports Server (NTRS)
McElroy, Mark W.
2016-01-01
A formulation is presented for an enriched shell nite element capable of progressive damage simulation in composite laminates. The element uses a discrete adaptive splitting approach for damage representation that allows for a straightforward model creation procedure based on an initially low delity mesh. The enriched element is veri ed for Mode I, Mode II, and mixed Mode I/II delamination simulation using numerical benchmark data. Experimental validation is performed using test data from a delamination-migration experiment. Good correlation was found between the enriched shell element model results and the numerical and experimental data sets. The work presented in this paper is meant to serve as a rst milestone in the enriched element's development with an ultimate goal of simulating three-dimensional progressive damage processes in multidirectional laminates.
14 CFR 91.1069 - Flight crew: Instrument proficiency check requirements.
Code of Federal Regulations, 2010 CFR
2010-01-01
... procedures. The instrument approach procedure or procedures must include at least one straight-in approach... conducted to published minimums for that procedure. (d) The instrument proficiency checks required by... emergencies, and standard instrument approaches involving navigational facilities which that pilot is to be...
14 CFR 91.1069 - Flight crew: Instrument proficiency check requirements.
Code of Federal Regulations, 2011 CFR
2011-01-01
... procedures. The instrument approach procedure or procedures must include at least one straight-in approach... conducted to published minimums for that procedure. (d) The instrument proficiency checks required by... emergencies, and standard instrument approaches involving navigational facilities which that pilot is to be...
Oral cancer screening: serum Raman spectroscopic approach
NASA Astrophysics Data System (ADS)
Sahu, Aditi K.; Dhoot, Suyash; Singh, Amandeep; Sawant, Sharada S.; Nandakumar, Nikhila; Talathi-Desai, Sneha; Garud, Mandavi; Pagare, Sandeep; Srivastava, Sanjeeva; Nair, Sudhir; Chaturvedi, Pankaj; Murali Krishna, C.
2015-11-01
Serum Raman spectroscopy (RS) has previously shown potential in oral cancer diagnosis and recurrence prediction. To evaluate the potential of serum RS in oral cancer screening, premalignant and cancer-specific detection was explored in the present study using 328 subjects belonging to healthy controls, premalignant, disease controls, and oral cancer groups. Spectra were acquired using a Raman microprobe. Spectral findings suggest changes in amino acids, lipids, protein, DNA, and β-carotene across the groups. A patient-wise approach was employed for data analysis using principal component linear discriminant analysis. In the first step, the classification among premalignant, disease control (nonoral cancer), oral cancer, and normal samples was evaluated in binary classification models. Thereafter, two screening-friendly classification approaches were explored to further evaluate the clinical utility of serum RS: a single four-group model and normal versus abnormal followed by determining the type of abnormality model. Results demonstrate the feasibility of premalignant and specific cancer detection. The normal versus abnormal model yields better sensitivity and specificity rates of 64 and 80% these rates are comparable to standard screening approaches. Prospectively, as the current screening procedure of visual inspection is useful mainly for high-risk populations, serum RS may serve as a useful adjunct for early and specific detection of oral precancers and cancer.
ERIC Educational Resources Information Center
Patterson, Lotsee
This manual resulted from a 2-year project to improve, develop, and expand public library and information services to American Indians and Alaska Natives. Designed to serve as a guide for tribal and community librarians who may lack professional training, the manual offers descriptions of library services, procedures, and management issues. An…
ERIC Educational Resources Information Center
Dauenhauer, Brian D.; Keating, Xiaofen D.; Lambdin, Dolly
2018-01-01
Purpose: This study aimed to conduct an in-depth investigation into physical education data sources and collection procedures in a district that was awarded a Physical Education Program (PEP) grant. Method: A qualitative, multi-site case study was conducted in which a single school district was the overarching case and eight schools served as…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-07
... governmental entities participating under 10 CFR 2.315(c), must be filed in accordance with the NRC E-Filing rule (72 FR 49139, August 28, 2007). The E-Filing process requires participants to submit and serve all... procedures described below. To comply with the procedural requirements of E-Filing, at least ten 10 days...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-10
... governmental entities participating under 10 CFR 2.315(c), must be filed in accordance with the NRC E-Filing rule (72 FR 49139, August 28, 2007). The E-Filing process requires participants to submit and serve all... accordance with the procedures described below. To comply with the procedural requirements of E-Filing, at...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-21
... governmental entities participating under 10 CFR 2.315(c), must be filed in accordance with the NRC E-Filing rule (72 FR 49139, August 28, 2007). The E-Filing process requires participants to submit and serve all... procedures described below. To comply with the procedural requirements of E-Filing, at least ten (10) days...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-11
... governmental entities participating under 10 CFR 2.315(c), must be filed in accordance with the NRC E-Filing rule (72 FR 49139, August 28, 2007). The E-Filing process requires participants to submit and serve all... procedures described below. To comply with the procedural requirements of E-Filing, at least ten (10) days...
Evaluating the Effects of a Video Prompt in a System of Least Prompts Procedure
ERIC Educational Resources Information Center
Smith, Katie A.; Ayres, Kevin M.; Mechling, Linda C.; Alexander, Jennifer L.; Mataras, Theologia K.; Shepley, Sally B.
2015-01-01
The purpose of this study was to evaluate the effects of a system of least prompts procedure with a video prompt serving as the model in teaching office tasks to three high school students with moderate intellectual disability. A multiple probe across behaviors design replicated across participants was used to evaluate the intervention. The…
Code of Federal Regulations, 2010 CFR
2010-07-01
... PROCESSES Service of Process § 205.12 Process served on the Register of Copyrights or an employee in his or... and mode of service. (d) The Office will accept service of process for an employee only when the legal... procedure. Service of process in this case is inadequate when made only on the General Counsel. An employee...
NASA Technical Reports Server (NTRS)
Perry, J. L.
2017-01-01
Contamination of a crewed spacecraft's cabin environment leading to environmental control and life support system (ECLSS) functional capability and operational margin degradation or loss can have an adverse effect on NASA's space exploration mission figures of merit-safety, mission success, effectiveness, and affordability. The role of evaluating the ECLSS's compatibility and cabin environmental impact as a key component of pass trace contaminant control is presented and the technical approach is described in the context of implementing NASA's safety and mission success objectives. Assessment examples are presented for a variety of chemicals used in vehicle systems and experiment hardware for the International Space Station program. The ECLSS compatibility and cabin environmental impact assessment approach, which can be applied to any crewed spacecraft development and operational effort, can provide guidance to crewed spacecraft system and payload developers relative to design criteria assigned ECLSS compatibility and cabin environmental impact ratings can be used by payload and system developers as criteria for ensuring adequate physical and operational containment. In additional to serving as an aid for guiding containment design, the assessments can guide flight rule and procedure development toward protecting the ECLSS as well as approaches for contamination event remediation.
Spectrometric microbiological analyzer
NASA Astrophysics Data System (ADS)
Schlager, Kenneth J.; Meissner, Ken E.
1996-04-01
Currently, there are four general approaches to microbiological analysis, i.e., the detection, identification and quantification of micro-organisms: (1) Traditional culturing and staining procedures, metabolic fermentations and visual morphological characteristics; (2) Immunological approaches employing microbe-specific antibodies; (3) Biotechnical techniques employing DNA probes and related genetic engineering methods; and (4) Physical measurement techniques based on the biophysical properties of micro-organisms. This paper describes an instrumentation development in the fourth of the above categories, physical measurement, that uses a combination of fluorometric and light scatter spectra to detect and identify micro-organisms at the species level. A major advantage of this approach is the rapid turnaround possible in medical diagnostic or water testing applications. Fluorometric spectra serve to define the biochemical characteristics of the microbe, and light scatter spectra the size and shape morphology. Together, the two spectra define a 'fingerprint' for each species of microbe for detection, identification and quantification purposes. A prototype instrument has been developed and tested under NASA sponsorship based on fluorometric spectra alone. This instrument demonstrated identification and quantification capabilities at the species level. The paper reports on test results using this instrument, and the benefits of employing a combination of fluorometric and light scatter spectra.
45 CFR 155.210 - Navigator program standards.
Code of Federal Regulations, 2013 CFR
2013-10-01
... underserved and vulnerable populations; (ii) Eligibility and enrollment rules and procedures; (iii) The range... population being served by the Exchange, including individuals with limited English proficiency, and ensure...
A method of setting limits for the purpose of quality assurance
NASA Astrophysics Data System (ADS)
Sanghangthum, Taweap; Suriyapee, Sivalee; Kim, Gwe-Ya; Pawlicki, Todd
2013-10-01
The result from any assurance measurement needs to be checked against some limits for acceptability. There are two types of limits; those that define clinical acceptability (action limits) and those that are meant to serve as a warning that the measurement is close to the action limits (tolerance limits). Currently, there is no standard procedure to set these limits. In this work, we propose an operational procedure to set tolerance limits and action limits. The approach to establish the limits is based on techniques of quality engineering using control charts and a process capability index. The method is different for tolerance limits and action limits with action limits being categorized into those that are specified and unspecified. The procedure is to first ensure process control using the I-MR control charts. Then, the tolerance limits are set equal to the control chart limits on the I chart. Action limits are determined using the Cpm process capability index with the requirements that the process must be in-control. The limits from the proposed procedure are compared to an existing or conventional method. Four examples are investigated: two of volumetric modulated arc therapy (VMAT) point dose quality assurance (QA) and two of routine linear accelerator output QA. The tolerance limits range from about 6% larger to 9% smaller than conventional action limits for VMAT QA cases. For the linac output QA, tolerance limits are about 60% smaller than conventional action limits. The operational procedure describe in this work is based on established quality management tools and will provide a systematic guide to set up tolerance and action limits for different equipment and processes.
14 CFR 97.3 - Symbols and terms used in procedures.
Code of Federal Regulations, 2010 CFR
2010-01-01
... established on the intermediate course or final approach course. (2) Initial approach altitude is the altitude (or altitudes, in high altitude procedure) prescribed for the initial approach segment of an...: Speed 166 knots or more. Approach procedure segments for which altitudes (minimum altitudes, unless...
14 CFR 97.3 - Symbols and terms used in procedures.
Code of Federal Regulations, 2011 CFR
2011-01-01
... established on the intermediate course or final approach course. (2) Initial approach altitude is the altitude (or altitudes, in high altitude procedure) prescribed for the initial approach segment of an...: Speed 166 knots or more. Approach procedure segments for which altitudes (minimum altitudes, unless...
Examining Recall Memory in Infancy and Early Childhood Using the Elicited Imitation Paradigm.
Lukowski, Angela F; Milojevich, Helen M
2016-04-28
The ability to recall the past allows us to report on details of previous experiences, from the everyday to the significant. Because recall memory is commonly assessed using verbal report paradigms in adults, studying the development of this ability in preverbal infants and children proved challenging. Over the past 30 years, researchers have developed a non-verbal means of assessing recall memory known as the elicited or deferred imitation paradigm. In one variant of the procedure, participants are presented with novel three-dimensional stimuli for a brief baseline period before a researcher demonstrates a series of actions that culminate in an end- or goal-state. The participant is allowed to imitate the demonstrated actions immediately, after a delay, or both. Recall performance is then compared to baseline or to performance on novel control sequences presented at the same session; memory can be assessed for the individual target actions and the order in which they were completed. This procedure is an accepted analogue to the verbal report techniques used with adults, and it has served to establish a solid foundation of the nature of recall memory in infancy and early childhood. In addition, the elicited or deferred imitation procedure has been modified and adapted to answer questions relevant to other aspects of cognitive functioning. The broad utility and application of imitation paradigms is discussed, along with limitations of the approach and directions for future research.
14 CFR 121.567 - Instrument approach procedures and IFR landing minimums.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Instrument approach procedures and IFR landing minimums. 121.567 Section 121.567 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... approach at an airport except in accordance with IFR weather minimums and instrument approach procedures...
14 CFR 121.567 - Instrument approach procedures and IFR landing minimums.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Instrument approach procedures and IFR landing minimums. 121.567 Section 121.567 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... approach at an airport except in accordance with IFR weather minimums and instrument approach procedures...
14 CFR 121.567 - Instrument approach procedures and IFR landing minimums.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Instrument approach procedures and IFR landing minimums. 121.567 Section 121.567 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... approach at an airport except in accordance with IFR weather minimums and instrument approach procedures...
14 CFR 121.567 - Instrument approach procedures and IFR landing minimums.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Instrument approach procedures and IFR landing minimums. 121.567 Section 121.567 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... approach at an airport except in accordance with IFR weather minimums and instrument approach procedures...
14 CFR 121.567 - Instrument approach procedures and IFR landing minimums.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Instrument approach procedures and IFR landing minimums. 121.567 Section 121.567 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... approach at an airport except in accordance with IFR weather minimums and instrument approach procedures...
A Decade of Experience With the Primary Pull-Through for Hirschsprung Disease in the Newborn Period
Teitelbaum, Daniel H.; Cilley, Robert E.; Sherman, Neil J.; Bliss, David; Uitvlugt, Neal D.; Renaud, Elizabeth J.; Kirstioglu, Irfan; Bengston, Tamara; Coran, Arnold G.
2000-01-01
Objective To determine whether use of a primary pull-through would result in equivalent perioperative and long-term complications compared with the two-stage approach. Summary Background Data During the past decade, the authors have advanced the use of a primary pull-through for Hirschsprung disease in the newborn, and preliminary results have suggested excellent outcomes. Methods From May 1989 through September 1999, 78 infants underwent a primary endorectal pull-through (ERPT) procedure at four pediatric surgical sites. Data were collected from medical records and a parental telephone interview (if the child was older than 3 years) to assess stooling patterns. A similar group of patients treated in a two-stage fashion served as a historical control. Results Mean age at the time of ERPT was 17.8 days of life. Comparing primary ERPT with a two-stage approach showed a trend toward a higher incidence of enterocolitis in the primary ERPT group compared with those with a two-stage approach (42.0% vs. 22.0%). Other complications were either lower in the primary ERPT group or similar, including rate of soiling and development of a bowel obstruction. Median number of stools per day was two at a mean follow-up of 4.1 ± 2.5 years, with 83% having three or fewer stools per day. Conclusions Performance of a primary ERPT for Hirschsprung disease in the newborn is an excellent option. Results were comparable to those of the two-stage procedure. The greater incidence of enterocolitis appears to be due to a lower threshold in diagnosing enterocolitis in more recent years. PMID:10973387
45 CFR 155.210 - Navigator program standards.
Code of Federal Regulations, 2012 CFR
2012-10-01
... underserved and vulnerable populations; (ii) Eligibility and enrollment rules and procedures; (iii) The range... manner that is culturally and linguistically appropriate to the needs of the population being served by...
1981-09-01
centers (OACCs), while units serving oceanic and domestic CTAs are area control centers ( ACCa ). Flight information centers (FICs) provide the non-ATC...Shanwick OACC, and also might be applied by the Santa Maria and Reykjavik ACCa . An alternative procedure permits the inclusion of altitude or time...OACCs), while units serving oceanic and domestic CTAs are area control centers ( ACCa ). Although control centers generally have responsibility for total
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 22 2010-07-01 2010-07-01 false What procedures allow the Administrator to object to a proposed small system variance or overturn a granted small system variance for a public water system serving 3,300 or fewer persons? 142.311 Section 142.311 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER...
Xiping Wang; Marko Teder; James Wacker
2013-01-01
This paper reports an in situ inspection project conducted on heavy timber structures of a century-old industrial building at a paper manufacturing facility. A nondestructive inspection procedure was employed to evaluate the true condition of the heavy timbers that serve as the main framing structure of the building. The on-site investigation involved monitoring of the...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-31
... entities participating under 10 CFR 2.315(c), must be filed in accordance with the NRC E-Filing rule (72 FR 49139; August 28, 2007). The E-Filing process requires participants to submit and serve all adjudicatory... procedures described below. To comply with the procedural requirements of E-Filing, at least 10 days prior to...
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 23 2014-07-01 2014-07-01 false What procedures allow the Administrator to object to a proposed small system variance or overturn a granted small system variance for a public water system serving 3,300 or fewer persons? 142.311 Section 142.311 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER...
Ho, Sirikit; Lukacs, Zoltan; Hoffmann, Georg F; Lindner, Martin; Wetter, Thomas
2007-07-01
In newborn screening with tandem mass spectrometry, multiple intermediary metabolites are quantified in a single analytical run for the diagnosis of fatty-acid oxidation disorders, organic acidurias, and aminoacidurias. Published diagnostic criteria for these disorders normally incorporate a primary metabolic marker combined with secondary markers, often analyte ratios, for which the markers have been chosen to reflect metabolic pathway deviations. We applied a procedure to extract new markers and diagnostic criteria for newborn screening to the data of newborns with confirmed medium-chain acyl-CoA dehydrogenase deficiency (MCADD) and a control group from the newborn screening program, Heidelberg, Germany. We validated the results with external data of the screening center in Hamburg, Germany. We extracted new markers by performing a systematic search for analyte combinations (features) with high discriminatory performance for MCADD. To select feature thresholds, we applied automated procedures to separate controls and cases on the basis of the feature values. Finally, we built classifiers from these new markers to serve as diagnostic criteria in screening for MCADD. On the basis of chi(2) scores, we identified approximately 800 of >628,000 new analyte combinations with superior discriminatory performance compared with the best published combinations. Classifiers built with the new features achieved diagnostic sensitivities and specificities approaching 100%. Feature construction methods provide ways to disclose information hidden in the set of measured analytes. Other diagnostic tasks based on high-dimensional metabolic data might also profit from this approach.
[The hybrid operating room. Home of high-end intraoperative imaging].
Gebhard, F; Riepl, C; Richter, P; Liebold, A; Gorki, H; Wirtz, R; König, R; Wilde, F; Schramm, A; Kraus, M
2012-02-01
A hybrid operating room must serve the medical needs of different highly specialized disciplines. It integrates interventional techniques for cardiovascular procedures and allows operations in the field of orthopaedic surgery, neurosurgery and maxillofacial surgery. The integration of all steps such as planning, documentation and the procedure itself saves time and precious resources. The best available imaging devices and user interfaces reduce the need for extensive personnel in the OR and facilitate new minimally invasive procedures. The immediate possibility of postoperative control images in CT-like quality enables the surgeon to react to problems during the same procedure without the need for later revision.
Evaluating North Carolina Food Pantry Food Safety-Related Operating Procedures.
Chaifetz, Ashley; Chapman, Benjamin
2015-11-01
Almost one in seven American households were food insecure in 2012, experiencing difficulty in providing enough food for all family members due to a lack of resources. Food pantries assist a food-insecure population through emergency food provision, but there is a paucity of information on the food safety-related operating procedures used in the pantries. Food pantries operate in a variable regulatory landscape; in some jurisdictions, they are treated equivalent to restaurants, while in others, they operate outside of inspection regimes. By using a mixed methods approach to catalog the standard operating procedures related to food in 105 food pantries from 12 North Carolina counties, we evaluated their potential impact on food safety. Data collected through interviews with pantry managers were supplemented with observed food safety practices scored against a modified version of the North Carolina Food Establishment Inspection Report. Pantries partnered with organized food bank networks were compared with those that operated independently. In this exploratory research, additional comparisons were examined for pantries in metropolitan areas versus nonmetropolitan areas and pantries with managers who had received food safety training versus managers who had not. The results provide a snapshot of how North Carolina food pantries operate and document risk mitigation strategies for foodborne illness for the vulnerable populations they serve. Data analysis reveals gaps in food safety knowledge and practice, indicating that pantries would benefit from more effective food safety training, especially focusing on formalizing risk management strategies. In addition, new tools, procedures, or policy interventions might improve information actualization by food pantry personnel.
A manual therapy and exercise approach to meralgia paresthetica in pregnancy: a case report
Skaggs, Clayton D.; Winchester, Brett A.; Vianin, Michael; Prather, Heidi
2006-01-01
Abstract Objective To present a case of a pregnant patient with meralgia paresthetica who improved using manual therapy and exercise procedures. Clinical Features A 22-year-old patient in the sixteenth week of pregnancy had low back pain, bilateral anterolateral thigh paresthesia and groin pain for a duration of 1 month. She had no motor deficits in either lower extremity and her reflexes were intact. As a standard clinic procedure, a battery of functional tests were performed including: active straight leg raise, long dorsal ligament test, and the pelvic pain provocation procedure. Based on her clinical history and physical responses to the aforementioned functional tests, the diagnosis of meralgia paresthetica was deduced. Intervention and Outcome Treatment was provided at 6 visits over a 6-week period where the patient underwent evaluation, manual intervention, and exercise prescription. Active Release Technique (ART) was performed to the restricted right sacroiliac (SIJ) complex and quadratus lumborum muscles. ART and post-isometric relaxation were applied to the illiopsoas muscles. The home exercise program consisted of pelvic/low back mobility, stabilization and relaxation exercises. After 6 treatments, the patient reported complete resolution of low back pain and left lower extremity symptoms and a 90% improvement in the right thigh symptoms. At her one-year follow-up, the patient reported no further complications and the absence of pain. Conclusions Manual therapy and exercises may serve as an effective treatment protocol for pregnant patients experiencing low back pain complicated by paresthesia. Because these conservative procedures offer a low-risk intervention, additional clinical studies are warranted to further study this treatment. PMID:19674679
Who is a cardiologist: Usurpers spawn?
Mishra, Sundeep
2015-01-01
Cerebrovascular disease is the number one killer worldwide. It is increasing in epidemic proportion in developing countries as well, including India. Trained cardiologists are few and scattered in urban areas and there exists a huge shortage of personnel in clinical arena of cardiology specialty. The problem is manifest not only in diagnostics but also in treatment. This space is appropriated by a large number of clinical professionals posing as true cardiologists. Thus, currently there is a critical need to define who can be called a cardiologist and who can be accorded the privilege to treat and even perform interventional procedures. Further, the only credible way to fill this gap is to increase the infrastructure, the staff and the number of teaching, academic hospitals so that there could be an increase in the number of trained cardiologists. Alternate approach to dilute the educational, skill, and experience requirements of the physicians so that more can qualify to be called as cardiologists is likely to be counter-productive since this approach will lead to dilution in the quality of cardiologists which will consequently lead to dilution in the quality of health-care delivery. Further, the irony of matter is that while the pool of cardiologist is increased with the plea of serving rural areas, the hard reality is that very few if any of these so-called trained physicians ever serve the rural area. Thus, it is in this context the tendency to follow the second course should be firmly resisted as also the need to define “who is a cardiologist.” PMID:26702675
Preformed titanium cranioplasty after resection of skull base meningiomas - a technical note.
Schebesch, Karl-Michael; Höhne, Julius; Gassner, Holger G; Brawanski, Alexander
2013-12-01
Meningiomas of the fronto-basal skull are difficult to manage as the treatment usually includes extensive resection of the lesion, consecutive reconstruction of the meninges and of the skull. Especially after removal of spheno-orbital and sphenoid-wing meningiomas, the cosmetic result is of utmost importance. In this technical note, we present our institutional approach in the treatment of skull base meningiomas, focussing on the reconstruction of the neurocranium with individually preformed titanium cranioplasty (CRANIOTOP(®), CL Instruments, Germany). Two female patients (40 years, 64 years) are presented. Both patients presented with skull base lesions suggestive of meningiomas. The preoperative thin-sliced CT scan was processed to generate a 3D-model of the skull. On it, the resection was mapped and following a simulated resection, the cranioplasty was manufactured. Intra-operatively, the titanium plate served as a template for the skull resection and was implanted after microsurgical tumour removal, consecutively. The cosmetic result was excellent. Immediate postoperative CT scan revealed accurate fitting and complete tumour removal. Control Magnetic Resonance Imaging (MRI) within 12 weeks was possible without any artifacts. The comprehensive approach described indicates only one surgical procedure for tumour removal and for reconstruction of the skull. The titanium plate served as an exact template for complete resection of the osseous parts of the tumour. Cosmetic outcome was excellent and control MRI was possible post operatively. CRANIOTOP(®) cranioplasty is a safe and practical tool for reconstruction of the skull after meningioma surgery. Copyright © 2013 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.
Procedure for extraction of disparate data from maps into computerized data bases
NASA Technical Reports Server (NTRS)
Junkin, B. G.
1979-01-01
A procedure is presented for extracting disparate sources of data from geographic maps and for the conversion of these data into a suitable format for processing on a computer-oriented information system. Several graphic digitizing considerations are included and related to the NASA Earth Resources Laboratory's Digitizer System. Current operating procedures for the Digitizer System are given in a simplified and logical manner. The report serves as a guide to those organizations interested in converting map-based data by using a comparable map digitizing system.
Software design for automated assembly of truss structures
NASA Technical Reports Server (NTRS)
Herstrom, Catherine L.; Grantham, Carolyn; Allen, Cheryl L.; Doggett, William R.; Will, Ralph W.
1992-01-01
Concern over the limited intravehicular activity time has increased the interest in performing in-space assembly and construction operations with automated robotic systems. A technique being considered at LaRC is a supervised-autonomy approach, which can be monitored by an Earth-based supervisor that intervenes only when the automated system encounters a problem. A test-bed to support evaluation of the hardware and software requirements for supervised-autonomy assembly methods was developed. This report describes the design of the software system necessary to support the assembly process. The software is hierarchical and supports both automated assembly operations and supervisor error-recovery procedures, including the capability to pause and reverse any operation. The software design serves as a model for the development of software for more sophisticated automated systems and as a test-bed for evaluation of new concepts and hardware components.
Czaplicki, Jerzy; Cornélissen, Germaine; Halberg, Franz
2009-01-01
Summary Transyears in biology have been documented thus far by the extended cosinor approach, including linear-nonlinear rhythmometry. We here confirm the existence of transyears by simulated annealing, a method originally developed for a much broader use, but described and introduced herein for validating its application to time series. The method is illustrated both on an artificial test case with known components and on biological data. We provide a table comparing results by the two methods and trust that the procedure will serve the budding sciences of chronobiology (the study of mechanisms underlying biological time structure), chronomics (the mapping of time structures in and around us), and chronobioethics, using the foregoing disciplines to add to concern for illnesses of individuals, and to budding focus on diseases of nations and civilizations. PMID:20414480
Problem of data quality and the limitations of the infrastructure approach
NASA Astrophysics Data System (ADS)
Behlen, Fred M.; Sayre, Richard E.; Rackus, Edward; Ye, Dingzhong
1998-07-01
The 'Infrastructure Approach' is a PACS implementation methodology wherein the archive, network and information systems interfaces are acquired first, and workstations are installed later. The approach allows building a history of archived image data, so that most prior examinations are available in digital form when workstations are deployed. A limitation of the Infrastructure Approach is that the deferred use of digital image data defeats many data quality management functions that are provided automatically by human mechanisms when data is immediately used for the completion of clinical tasks. If the digital data is used solely for archiving while reports are interpreted from film, the radiologist serves only as a check against lost films, and another person must be designated as responsible for the quality of the digital data. Data from the Radiology Information System and the PACS were analyzed to assess the nature and frequency of system and data quality errors. The error level was found to be acceptable if supported by auditing and error resolution procedures requiring additional staff time, and in any case was better than the loss rate of a hardcopy film archive. It is concluded that the problem of data quality compromises but does not negate the value of the Infrastructure Approach. The Infrastructure Approach should best be employed only to a limited extent, and that any phased PACS implementation should have a substantial complement of workstations dedicated to softcopy interpretation for at least some applications, and with full deployment following not long thereafter.
General Aviation Flight Test of Advanced Operations Enabled by Synthetic Vision
NASA Technical Reports Server (NTRS)
Glaab, Louis J.; Hughhes, Monica F.; Parrish, Russell V.; Takallu, Mohammad A.
2014-01-01
A flight test was performed to compare the use of three advanced primary flight and navigation display concepts to a baseline, round-dial concept to assess the potential for advanced operations. The displays were evaluated during visual and instrument approach procedures including an advanced instrument approach resembling a visual airport traffic pattern. Nineteen pilots from three pilot groups, reflecting the diverse piloting skills of the General Aviation pilot population, served as evaluation subjects. The experiment had two thrusts: 1) an examination of the capabilities of low-time (i.e., <400 hours), non-instrument-rated pilots to perform nominal instrument approaches, and 2) an exploration of potential advanced Visual Meteorological Conditions (VMC)-like approaches in Instrument Meteorological Conditions (IMC). Within this context, advanced display concepts are considered to include integrated navigation and primary flight displays with either aircraft attitude flight directors or Highway In The Sky (HITS) guidance with and without a synthetic depiction of the external visuals (i.e., synthetic vision). Relative to the first thrust, the results indicate that using an advanced display concept, as tested herein, low-time, non-instrument-rated pilots can exhibit flight-technical performance, subjective workload and situation awareness ratings as good as or better than high-time Instrument Flight Rules (IFR)-rated pilots using Baseline Round Dials for a nominal IMC approach. For the second thrust, the results indicate advanced VMC-like approaches are feasible in IMC, for all pilot groups tested for only the Synthetic Vision System (SVS) advanced display concept.
Assessment of Proficiency and Competency in Laboratory Animal Biomethodologies
Clifford, Paula; Melfi, Natasha; Bogdanske, John; Johnson, Elizabeth J; Kehler, James; Baran, Szczepan W
2013-01-01
Personnel working with laboratory animals are required by laws and guidelines to be trained and qualified to perform biomethodologic procedures. The assessment of competency and proficiency is a vital component of a laboratory animal training program, because this process confirms that the trainees have met the learning objectives for a particular procedure. The approach toward qualification assessment differs between organizations because laws and guidelines do not outline how the assessment should be performed or which methods and tools should be used. Assessment of clinical and surgical medicine has received considerable attention over the last few decades and has progressed from simple subjective methods to well-defined and objective methods of assessing competency. Although biomethodology competency and proficiency assessment is discussed in the literature, a standard and objective assessment method has not yet been developed. The development and implementation of an objective and standardized biomethodologic assessment program can serve as a tool to improve standards, ensure consistent training, and decrease research variables yet ensure animal welfare. Here we review the definition and goals of training and assessment, review assessment methods, and propose a method to develop a standard and objective assessment program for the laboratory animal science field, particularly training departments and IACUC. PMID:24351758
A novel procedure for the identification of chaos in complex biological systems
NASA Astrophysics Data System (ADS)
Bazeia, D.; Pereira, M. B. P. N.; Brito, A. V.; Oliveira, B. F. De; Ramos, J. G. G. S.
2017-03-01
We demonstrate the presence of chaos in stochastic simulations that are widely used to study biodiversity in nature. The investigation deals with a set of three distinct species that evolve according to the standard rules of mobility, reproduction and predation, with predation following the cyclic rules of the popular rock, paper and scissors game. The study uncovers the possibility to distinguish between time evolutions that start from slightly different initial states, guided by the Hamming distance which heuristically unveils the chaotic behavior. The finding opens up a quantitative approach that relates the correlation length to the average density of maxima of a typical species, and an ensemble of stochastic simulations is implemented to support the procedure. The main result of the work shows how a single and simple experimental realization that counts the density of maxima associated with the chaotic evolution of the species serves to infer its correlation length. We use the result to investigate others distinct complex systems, one dealing with a set of differential equations that can be used to model a diversity of natural and artificial chaotic systems, and another one, focusing on the ocean water level.
Synchronous exfoliation and assembly of graphene on 3D Ni(OH)2 for supercapacitors.
Ma, Liguo; Zheng, Maojun; Liu, Shaohua; Li, Qiang; You, Yuxiu; Wang, Faze; Ma, Li; Shen, Wenzhong
2016-11-08
Nowadays, new approaches to fabricate high-performance electrode materials are of vital importance in the renewable energy field. Here, we present a facile synthesis procedure of 3D Ni(OH) 2 /graphene hybrids for supercapacitors via synchronous electrochemical-assisted exfoliation and assembly of graphene on 3D Ni(OH) 2 networks. With the assistance of an electric field, the electrochemically exfoliated high-quality graphene can be readily, uniformly assembled on the surfaces of 3D Ni(OH) 2 . When serving as electrode materials for supercapacitors, the resulting 3D Ni(OH) 2 /graphene composites exhibited excellent specific capacitance (263 mF cm -2 at 2 mA cm -2 ), remarkable rate capability and super-long cycle life (retention of 94.1% even after 10 000 continuous charge-discharge cycles), which may be attributed to their highly porous, stable 3D architecture as well as uniform, firm anchoring of ultrathin graphene on their surfaces. Therefore, our approach provides a facile strategy for the large-scale synthesis of high-quality graphene based composites towards various applications.
Chai, Chen; Wong, Yiik Diew; Wang, Xuesong
2017-07-01
This paper proposes a simulation-based approach to estimate safety impact of driver cognitive failures and driving errors. Fuzzy Logic, which involves linguistic terms and uncertainty, is incorporated with Cellular Automata model to simulate decision-making process of right-turn filtering movement at signalized intersections. Simulation experiments are conducted to estimate the relationships between cognitive failures and driving errors with safety performance. Simulation results show Different types of cognitive failures are found to have varied relationship with driving errors and safety performance. For right-turn filtering movement, cognitive failures are more likely to result in driving errors with denser conflicting traffic stream. Moreover, different driving errors are found to have different safety impacts. The study serves to provide a novel approach to linguistically assess cognitions and replicate decision-making procedures of the individual driver. Compare to crash analysis, the proposed FCA model allows quantitative estimation of particular cognitive failures, and the impact of cognitions on driving errors and safety performance. Copyright © 2017 Elsevier Ltd. All rights reserved.
A new lumped-parameter model for flow in unsaturated dual-porosity media
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zimmerman, Robert W.; Hadgu, Teklu; Bodvarsson, Gudmundur S.
A new lumped-parameter approach to simulating unsaturated flow processes in dual-porosity media such as fractured rocks or aggregated soils is presented. Fluid flow between the fracture network and the matrix blocks is described by a non-linear equation that relates the imbibition rate to the local difference in liquid-phase pressure between the fractures and the matrix blocks. Unlike a Warren-Root-type equation, this equation is accurate in both the early and late time regimes. The fracture/matrix interflow equation has been incorporated into an existing unsaturated flow simulator, to serve as a source/sink term for fracture gridblocks. Flow processes are then simulated usingmore » only fracture gridblocks in the computational grid. This new lumped-parameter approach has been tested on two problems involving transient flow in fractured/porous media, and compared with simulations performed using explicit discretization of the matrix blocks. The new procedure seems to accurately simulate flow processes in unsaturated fractured rocks, and typically requires an order of magnitude less computational time than do simulations using fully-discretized matrix blocks. [References: 37]« less
NASA Astrophysics Data System (ADS)
Wu, Qiang; Zhou, Wanfang; Wang, Jinhua; Xie, Shuhan
2009-05-01
Groundwater inrush is a geohazard that can significantly impact safe operations of the coal mines in China. Its occurrence is controlled by many factors and processes are often not amenable to mathematical expressions. To evaluate the water inrush risk, Professor Wu and his colleagues have proposed the vulnerability index approach by coupling the artificial neural network (ANN) and geographic information system (GIS). The detailed procedures of using this innovative approach are shown in a case study. Firstly, the powerful spatial data analysis functions of GIS was used to establish the thematic layer of each of the main factors that control the water inrush, and then to choose the training sample on the thematic layer with the ANN-BP Arithmetic. Secondly, the ANN evaluation model of the water inrush was established to determine the threshold value for each risk level with a histogram of the water inrush vulnerability index. As a result, the mine area was divided into four regions with different vulnerability levels and they served as the general guidelines for the mine operations.
Labeling Biomolecules with Radiorhenium - a Review of the Bifunctional Chelators
Liu, Guozheng; Hnatowich, Donald J.
2007-01-01
For radiotherapy, biomolecules such as intact antibodies, antibody fragments, peptides, DNAs and other oligomers have all been labeled with radiorhenium (186Re and 188Re). Three different approaches have been employed that may be referred to as direct, indirect and integral labeling. Direct labeling applies to proteins and involves the initial reduction of endogenous disulfide bridges to provide chelation sites. Indirect labeling can apply to most biomolecules and involves the initial attachment of an exogenous chelator. Finally, integral labeling is a special case applying only to small molecules in which the metallic radionuclide serves to link two parts of a biomolecule together in forming the labeled complex. While the number of varieties for the direct and integral radiolabeling approaches is rather limited, a fairly large and diverse number of chelators have been reported in the case of indirect labeling. Our objective herein is to provide an overview of the various chelators that have been used in the indirect labeling of biomolecules with radiorhenium, including details on the labeling procedures, the stability of the radiolabel and, where possible, the influence of the label on biological properties. PMID:17504162
Code of Federal Regulations, 2010 CFR
2010-04-01
... evidence; (d) take or cause depositions to be taken whenever the ends of justice would be served thereby... the issues by consent of the parties; (g) dispose of procedural requests or similar matters; (h...
Code of Federal Regulations, 2014 CFR
2014-04-01
... evidence; (d) take or cause depositions to be taken whenever the ends of justice would be served thereby... the issues by consent of the parties; (g) dispose of procedural requests or similar matters; (h...
Code of Federal Regulations, 2012 CFR
2012-04-01
... evidence; (d) take or cause depositions to be taken whenever the ends of justice would be served thereby... the issues by consent of the parties; (g) dispose of procedural requests or similar matters; (h...
Code of Federal Regulations, 2013 CFR
2013-04-01
... evidence; (d) take or cause depositions to be taken whenever the ends of justice would be served thereby... the issues by consent of the parties; (g) dispose of procedural requests or similar matters; (h...
Code of Federal Regulations, 2011 CFR
2011-04-01
... evidence; (d) take or cause depositions to be taken whenever the ends of justice would be served thereby... the issues by consent of the parties; (g) dispose of procedural requests or similar matters; (h...
32 CFR 865.3 - Application procedures.
Code of Federal Regulations, 2010 CFR
2010-07-01
... member served. (2) The member's social security number or Air Force service number. (3) The applicant's.... Applicants may withdraw an application at any time before the Board's decision. Withdrawal does not stay the...
78 FR 32085 - Amendment of Class E Airspace; Eureka, NV
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-29
... instrument approach procedures at the airport. This improves the safety and management of Instrument Flight... aircraft using the RNAV (GPS) standard instrument approach procedures at Eureka Airport. Class E airspace...) standard instrument approach procedures at the airport. Additional controlled airspace extending upward...
75 FR 62457 - Establishment of Class E Airspace; Port Clarence, AK
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-12
... airstrip and has developed a military-use instrument approach procedure. This instrument approach procedure... Class E airspace for air traffic management of Instrument Flight Rules (IFR) operations. DATES... published in the notice of proposed rulemaking. The establishment of an instrument approach procedure...
DOT National Transportation Integrated Search
2008-06-01
This report serves as a comprehensive guide to traffic signal timing and documents the tasks completed in association with its : development. The focus of this document is on traffic signal control principles, practices, and procedures. It describes ...
Monitoring Air Quality with Leaf Yeasts.
ERIC Educational Resources Information Center
Richardson, D. H. S.; And Others
1985-01-01
Proposes that leaf yeast serve as quick, inexpensive, and effective techniques for monitoring air quality. Outlines procedures and provides suggestions for data analysis. Includes results from sample school groups who employed this technique. (ML)
13 CFR 120.810 - Applications for certification as a CDC.
Code of Federal Regulations, 2010 CFR
2010-01-01
... LOANS Development Company Loan Program (504) Certification Procedures to Become A Cdc § 120.810... District Office serving the jurisdiction in which the applicant has or proposes to locate its headquarters...
The CIPM list of recommended frequency standard values: guidelines and procedures
NASA Astrophysics Data System (ADS)
Riehle, Fritz; Gill, Patrick; Arias, Felicitas; Robertsson, Lennart
2018-04-01
A list of standard reference frequency values (LoF) of quantum transitions from the microwave to the optical regime has been recommended by the International Committee for Weights and Measures (Comité international des poids et mesures, CIPM) for use in basic research, technology, and for the metrology of time, frequency and length. The CIPM LoF contains entries that are recommended as secondary representations of the second in the International System of Units, and entries that can be used to serve as realizations of the definition of the metre. The historical perspective that led to the CIPM LoF is outlined. Procedures have been developed for updating existing, and validating new, entries into the CIPM LoF. The CIPM LoF might serve as an entry for a future redefinition of the second by an optical transition.
Manpower and Personnel Requirements Determination Methodologies (MANPERS).
1984-12-01
Landing Ship Dock ( LSD -4) propulsion system 3. Advanced Light Weight Torpedo 4. A new destroyer class (DDGX) 5. Undergraduate Jet Flight Training System...The pragmatic norm considers a theory acceptable to the extent it serves the scientific purpose for which it was designed. F -14 Shaw and Costanzo (1970...invalidated. * The usual procedure is revision either of procedures or theoretical * structure. Shaw and Costanzo (1970) further specified five desirable (but
Analysis of Chitin in Contaminated Fuels
1975-09-01
medium (12) Glucosamine hydrochloride (Iml = 8.6 mg glucosamine ). Store frozen at -IOOC. 2. Procedure. a. Take at least 10 bottles (bottle dimensions are...DISCUSSION 6. Discussion 5 V CONCLUSIONS 7. Conclusions 5 :1IBLIOGRAPHY 7 APIYFNDIX - Analytical Procedure for the Determination of Chitin As Glucosamine 8...concentration of the aminosugar. Chitin, a polymer of glucosamine . is present in the cell wall of most fungi3 and, thus, if determined quantitatively serves to
[Benefit assessment of operative interventions from the perspective of surgical research].
Hüttner, F J; Ulrich, A; Mihaljevic, A L; Probst, P; Rossion, I; Diener, Markus K
2015-03-01
The benefit assessment of surgical procedures serves as the basis for the concept of evidence-based surgery. However, especially in the field of surgery, many interventions are lacking assessment in high-quality clinical trials. Therefore, a well-structured benefit assessment of surgical interventions in the future is imperative. Considering the different perspectives, e.g. of the patients, surgeons, industry or health care investors, the implications of the benefits and risks of a procedure can differ significantly. Researchers have to abide by different regulations, depending on the type of intervention being evaluated in a surgical trial. Furthermore, the benefit assessment of surgical procedures poses specific challenges, from the choice of a relevant endpoint to issues concerning the standardization of the interventions and the impact of learning curves. The IDEAL concept, which was established by a group of international experts in 2009, serves as a framework for the future development and assessment of innovations in the field of surgery. For example, the SDGC (Study Center of the German Society of Surgery) and CHIR-Net (Surgical Studies Network) indicate that such collaborations of clinicians and methodologists can lead to the creation of a qualified structure for the effective benefit assessment of surgical procedures. In the future, the aforementioned evidence gaps must be eliminated and innovations evaluated efficiently by the work of such networks.
Risher, D W; Zhang, X; Kostarczyk, E; Gokin, A P; Honda, C N; Giesler, G J
1997-04-25
We developed a relatively inexpensive method for stereotaxic placement of electrodes or needles in the brains of monkeys. Steel balls were affixed to the skulls of monkeys. These balls served as fiducial markers and were also used as points at which the monkey's skull was held in a modified stereotaxic apparatus. Computed tomography (CT) was used to establish the location of an injection target with respect to the fiducial markers. A computer program related the CT coordinates to stereotaxic coordinates. These were used to direct an electrode marker toward a target in the hypothalamus. With the marker left in place, the monkey was removed from the stereotaxic frame and a second CT scan was performed. Corrections for errors in marker placement were made and retrograde tracers were injected. This procedure was found to be more accurate and reliable than conventional stereotaxic procedures. The accuracy and repeatability of the technique were also established using a phantom model of a monkey's skull. Two important advantages of this method are that animals can be repeatedly placed into the stereotaxic frame in precisely the same position and that there are many opportunities during the procedure to check for and correct errors.
Lievens, Filip; Sackett, Paul R
2017-01-01
Past reviews and meta-analyses typically conceptualized and examined selection procedures as holistic entities. We draw on the product design literature to propose a modular approach as a complementary perspective to conceptualizing selection procedures. A modular approach means that a product is broken down into its key underlying components. Therefore, we start by presenting a modular framework that identifies the important measurement components of selection procedures. Next, we adopt this modular lens for reviewing the available evidence regarding each of these components in terms of affecting validity, subgroup differences, and applicant perceptions, as well as for identifying new research directions. As a complement to the historical focus on holistic selection procedures, we posit that the theoretical contributions of a modular approach include improved insight into the isolated workings of the different components underlying selection procedures and greater theoretical connectivity among different selection procedures and their literatures. We also outline how organizations can put a modular approach into operation to increase the variety in selection procedures and to enhance the flexibility in designing them. Overall, we believe that a modular perspective on selection procedures will provide the impetus for programmatic and theory-driven research on the different measurement components of selection procedures. (PsycINFO Database Record (c) 2017 APA, all rights reserved).
ERIC Educational Resources Information Center
Rosen-Reynoso, Myra; Kwan, Ngai; Blackburn, Nerlie; Sotnik, Paula; Manyibe, Edward O.; Moore, Corey L.
2017-01-01
Purpose: To describe the experience of implementing a collaborative model for research mentorship across various minority-serving institutions, specifically, historically Black colleges/universities (HBCUs), Hispanic-serving institutions (HSIs), and American Indian tribal colleges/universities (AITCUs). Methods: The peer-to-peer mentor research…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-27
...On September 14, 2011, the U.S. Department of Energy (DOE) issued a notice of proposed rulemaking (NOPR) to amend the test procedures for general service fluorescent lamps (GSFLs), general service incandescent lamps (GSILs), and incandescent reflector lamps (IRLs). That proposed rulemaking serves as the basis for today's action. DOE is amending its test procedures for GSFLs and GSILs established under the Energy Policy and Conservation Act (EPCA). DOE is not amending in this final rule the existing test procedure for IRLs established under EPCA. For GSFLs and GSILs, DOE is updating several references to the industry standards referenced in DOE's test procedures. DOE is also establishing a lamp lifetime test procedure for GSILs. These test procedures also provide the protocols upon which the Federal Trade Commission bases its energy guide label for these products. DOE's review of the GSFL, GSIL, and IRL test procedures fulfills the EPCA requirement that DOE review test procedures for all covered products at least once every seven years.
DOT National Transportation Integrated Search
2008-06-01
This report serves as a comprehensive guide to traffic signal timing and documents the tasks completed in association with its development. The focus of this document is on traffic signal control principles, practices, and procedures. It describes th...
16 CFR § 1502.20 - Authority of presiding officer.
Code of Federal Regulations, 2013 CFR
2013-01-01
... for filing pleadings; (j) Rule on motions and other procedural matters; (k) Rule on motions for... the presiding officer determines that no party will be prejudiced, the ends of justice will be served...
Code of Federal Regulations, 2010 CFR
2010-07-01
... default judgment cites alleged procedural irregularities in the proceeding below and not the merits of the... a hearing shall not be deemed to be a waiver of the right to be served with a copy of the...
30 CFR 75.900-3 - Testing, examination, and maintenance of circuit breakers; procedures.
Code of Federal Regulations, 2010 CFR
2010-07-01
... current circuits serving three-phase alternating current equipment and their auxiliary devices shall be... Underground Low- and Medium-Voltage Alternating Current Circuits § 75.900-3 Testing, examination, and...
30 CFR 77.900-1 - Testing, examination, and maintenance of circuit breakers; procedures.
Code of Federal Regulations, 2011 CFR
2011-07-01
... protecting low- and medium-voltage circuits serving portable or mobile three-phase alternating current... AND SURFACE WORK AREAS OF UNDERGROUND COAL MINES Low- and Medium-Voltage Alternating Current Circuits...
30 CFR 77.900-1 - Testing, examination, and maintenance of circuit breakers; procedures.
Code of Federal Regulations, 2010 CFR
2010-07-01
... protecting low- and medium-voltage circuits serving portable or mobile three-phase alternating current... AND SURFACE WORK AREAS OF UNDERGROUND COAL MINES Low- and Medium-Voltage Alternating Current Circuits...
30 CFR 75.900-3 - Testing, examination, and maintenance of circuit breakers; procedures.
Code of Federal Regulations, 2011 CFR
2011-07-01
... current circuits serving three-phase alternating current equipment and their auxiliary devices shall be... Underground Low- and Medium-Voltage Alternating Current Circuits § 75.900-3 Testing, examination, and...
Design and evaluation of instrument approach procedure charts
DOT National Transportation Integrated Search
1993-01-01
A new format for instrument approach procedure : charts has been designed. Special attention was paid to : improving the readability of communication frequencies, : approach course heading and missed approach instructions. : Selected components of th...
Vision based flight procedure stereo display system
NASA Astrophysics Data System (ADS)
Shen, Xiaoyun; Wan, Di; Ma, Lan; He, Yuncheng
2008-03-01
A virtual reality flight procedure vision system is introduced in this paper. The digital flight map database is established based on the Geographic Information System (GIS) and high definitions satellite remote sensing photos. The flight approaching area database is established through computer 3D modeling system and GIS. The area texture is generated from the remote sensing photos and aerial photographs in various level of detail. According to the flight approaching procedure, the flight navigation information is linked to the database. The flight approaching area vision can be dynamic displayed according to the designed flight procedure. The flight approaching area images are rendered in 2 channels, one for left eye images and the others for right eye images. Through the polarized stereoscopic projection system, the pilots and aircrew can get the vivid 3D vision of the flight destination approaching area. Take the use of this system in pilots preflight preparation procedure, the aircrew can get more vivid information along the flight destination approaching area. This system can improve the aviator's self-confidence before he carries out the flight mission, accordingly, the flight safety is improved. This system is also useful in validate the visual flight procedure design, and it helps to the flight procedure design.
Tewari, Satyendra; Sharma, Naveen; Kapoor, Aditya; Syal, Sanjeev Kumar; Kumar, Sudeep; Garg, Naveen; Goel, Pravin K
2013-01-01
With the increasing prevalence of coronary artery disease, percutaneous coronary artery procedures have become even more important. Our study has compared transradial to transfemoral artery approach for coronary procedures in Indian population. Comparison of transradial and transfemoral artery approach for percutaneous coronary procedures. 26,238 patients, who underwent percutaneous coronary artery procedures, were divided into two groups depending upon transradial and transfemoral artery approach and compared for the various demographic and clinical characteristics, risk factors profile, vascular access and procedural details. 26,238 patients underwent percutaneous coronary procedures at our center. 81% were male and 19% were female. 55.65% and 44.35% procedures were done through transfemoral and transradial approach, respectively. 17,417 (66.38%) coronary angiographies were done, out of which 53.92% were transradial and 46.08% were transfemoral procedures. 8821 (33.62%) Percutaneous Transluminal Coronary Angioplasty (PTCA) were done, out of which 25.46% and 74.54% were done through transradial and transfemoral approach, respectively. Mean fluoroscopy time was 4.40 ± 3.55 min for transradial and 3.30 ± 3.66 min for transfemoral CAG (p < 0.001). For PTCA mean fluoroscopy time was 13.53 ± 2.53 min for transradial and 12.61 ± 9.524 min for transfemoral PTCA (p < 0.001). Minor and major procedure related complications and total duration of hospital stay were lower in transradial as compared to transfemoral group. The number of percutaneous transradial procedures have increased significantly with reduced complication rates and comparable success rate to transfemoral approach, along with the additional benefits to patient in terms of patient comfort, preference and reduced cost of health delivery. Copyright © 2013 Cardiological Society of India. Published by Elsevier B.V. All rights reserved.
Huo, Zhimin; Summers, Ronald M.; Paquerault, Sophie; Lo, Joseph; Hoffmeister, Jeffrey; Armato, Samuel G.; Freedman, Matthew T.; Lin, Jesse; Ben Lo, Shih-Chung; Petrick, Nicholas; Sahiner, Berkman; Fryd, David; Yoshida, Hiroyuki; Chan, Heang-Ping
2013-01-01
Computer-aided detection/diagnosis (CAD) is increasingly used for decision support by clinicians for detection and interpretation of diseases. However, there are no quality assurance (QA) requirements for CAD in clinical use at present. QA of CAD is important so that end users can be made aware of changes in CAD performance both due to intentional or unintentional causes. In addition, end-user training is critical to prevent improper use of CAD, which could potentially result in lower overall clinical performance. Research on QA of CAD and user training are limited to date. The purpose of this paper is to bring attention to these issues, inform the readers of the opinions of the members of the American Association of Physicists in Medicine (AAPM) CAD subcommittee, and thus stimulate further discussion in the CAD community on these topics. The recommendations in this paper are intended to be work items for AAPM task groups that will be formed to address QA and user training issues on CAD in the future. The work items may serve as a framework for the discussion and eventual design of detailed QA and training procedures for physicists and users of CAD. Some of the recommendations are considered by the subcommittee to be reasonably easy and practical and can be implemented immediately by the end users; others are considered to be “best practice” approaches, which may require significant effort, additional tools, and proper training to implement. The eventual standardization of the requirements of QA procedures for CAD will have to be determined through consensus from members of the CAD community, and user training may require support of professional societies. It is expected that high-quality CAD and proper use of CAD could allow these systems to achieve their true potential, thus benefiting both the patients and the clinicians, and may bring about more widespread clinical use of CAD for many other diseases and applications. It is hoped that the awareness of the need for appropriate CAD QA and user training will stimulate new ideas and approaches for implementing such procedures efficiently and effectively as well as funding opportunities to fulfill such critical efforts. PMID:23822459
National Center for Standards and Certification Information: Service and programs
NASA Technical Reports Server (NTRS)
Overman, Joanne
1994-01-01
The National Center for Standards and Certification Information (NCSCI) provides information on U.S., foreign and international voluntary standards, government regulations, and conformity assessment procedures for non-agricultural products. The Center serves as a referral service and focal point in the United States for information on standards and standards-related information. NCSCI staff respond to inquiries, maintain a reference collection of standards and standards-related documents, and serve as the U.S. inquiry point for information to and from foreign countries.
Proposal for an Evaluation Method for the Performance of Work Procedures.
Mohammed, Mouda; Mébarek, Djebabra; Wafa, Boulagouas; Makhlouf, Chati
2016-12-01
Noncompliance of operators with work procedures is a recurrent problem. This human behavior has been said to be situational and studied by many different approaches (ergonomic and others), which consider the noncompliance with work procedures to be obvious and seek to analyze its causes as well as consequences. The object of the proposed method is to solve this problem by focusing on the performance of work procedures and ensuring improved performance on a continuous basis. This study has multiple results: (1) assessment of the work procedures' performance by a multicriteria approach; (2) the use of a continuous improvement approach as a framework for the sustainability of the assessment method of work procedures' performance; and (3) adaptation of the Stop-Card as a facilitator support for continuous improvement of work procedures. The proposed method emphasizes to put in value the inputs of continuous improvement of the work procedures in relation with the conventional approaches which adopt the obvious evidence of the noncompliance to the working procedures and seek to analyze the cause-effect relationships related to this unacceptable phenomenon, especially in strategic industry.
Intrasystem Analysis Program (IAP) Structural Design Study.
1981-06-01
accuracy constraints, and user competence . This report is designed to serve as a guide in con- structing procedures and identifying those aspects of the...parameters. 3.3.3 Userability The term "Userability" refers here to the level of competence assumed for an IAP analyst in need of a procedure. There...media the wires pass through is homogeneous along the length of the wires. Under these assumptions the wave propagation is predominantly tranverse
NASA Technical Reports Server (NTRS)
Gonzalez, Guillermo A.; Lucy, Melvin H.; Massie, Jeffrey J.
2013-01-01
The NASA Langley Research Center, Engineering Directorate, Electronic System Branch, is responsible for providing pyrotechnic support capabilities to Langley Research Center unmanned flight and ground test projects. These capabilities include device selection, procurement, testing, problem solving, firing system design, fabrication and testing; ground support equipment design, fabrication and testing; checkout procedures and procedure?s training to pyro technicians. This technical memorandum will serve as a guideline for the design, fabrication and testing of electropyrotechnic firing systems. The guidelines will discuss the entire process beginning with requirements definition and ending with development and execution.
14 CFR 97.3 - Symbols and terms used in procedures.
Code of Federal Regulations, 2014 CFR
2014-01-01
... procedures means helicopter procedures, with applicable minimums as prescribed in § 97.35. Helicopters may... above a designated helicopter landing area elevation used for helicopter instrument approach procedures... highest terrain/surface within a 5,200-foot radius of the missed approach point used in helicopter...
14 CFR 97.3 - Symbols and terms used in procedures.
Code of Federal Regulations, 2012 CFR
2012-01-01
... procedures means helicopter procedures, with applicable minimums as prescribed in § 97.35. Helicopters may... above a designated helicopter landing area elevation used for helicopter instrument approach procedures... highest terrain/surface within a 5,200-foot radius of the missed approach point used in helicopter...
14 CFR 97.3 - Symbols and terms used in procedures.
Code of Federal Regulations, 2013 CFR
2013-01-01
... procedures means helicopter procedures, with applicable minimums as prescribed in § 97.35. Helicopters may... above a designated helicopter landing area elevation used for helicopter instrument approach procedures... highest terrain/surface within a 5,200-foot radius of the missed approach point used in helicopter...
Laser scanning cytometry for automation of the micronucleus assay
Darzynkiewicz, Zbigniew; Smolewski, Piotr; Holden, Elena; Luther, Ed; Henriksen, Mel; François, Maxime; Leifert, Wayne; Fenech, Michael
2011-01-01
Laser scanning cytometry (LSC) provides a novel approach for automated scoring of micronuclei (MN) in different types of mammalian cells, serving as a biomarker of genotoxicity and mutagenicity. In this review, we discuss the advances to date in measuring MN in cell lines, buccal cells and erythrocytes, describe the advantages and outline potential challenges of this distinctive approach of analysis of nuclear anomalies. The use of multiple laser wavelengths in LSC and the high dynamic range of fluorescence and absorption detection allow simultaneous measurement of multiple cellular and nuclear features such as cytoplasmic area, nuclear area, DNA content and density of nuclei and MN, protein content and density of cytoplasm as well as other features using molecular probes. This high-content analysis approach allows the cells of interest to be identified (e.g. binucleated cells in cytokinesis-blocked cultures) and MN scored specifically in them. MN assays in cell lines (e.g. the CHO cell MN assay) using LSC are increasingly used in routine toxicology screening. More high-content MN assays and the expansion of MN analysis by LSC to other models (i.e. exfoliated cells, dermal cell models, etc.) hold great promise for robust and exciting developments in MN assay automation as a high-content high-throughput analysis procedure. PMID:21164197
Jasensky, Joshua; Swain, Jason E
2013-10-01
Embryo imaging has long been a critical tool for in vitro fertilization laboratories, aiding in morphological assessment of embryos, which remains the primary tool for embryo selection. With the recent emergence of clinically applicable real-time imaging systems to assess embryo morphokinetics, a renewed interest has emerged regarding noninvasive methods to assess gamete and embryo development as a means of inferring quality. Several studies exist that utilize novel imaging techniques to visualize or quantify intracellular components of gametes and embryos with the intent of correlating localization of organelles or molecular constitution with quality or outcome. However, the safety of these approaches varies due to the potential detrimental impact of light exposure or other variables. Along with complexity of equipment and cost, these drawbacks currently limit clinical application of these novel microscopes and imaging techniques. However, as evidenced by clinical incorporation of some real-time imaging devices as well as use of polarized microscopy, some of these imaging approaches may prove to be useful. This review summarizes the existing literature on novel imaging approaches utilized to examine gametes and embryos. Refinement of some of these imaging systems may permit clinical application and serve as a means to offer new, noninvasive selection tools to improve outcomes for various assisted reproductive technology procedures.
Dynamic alarm response procedures
DOE Office of Scientific and Technical Information (OSTI.GOV)
Martin, J.; Gordon, P.; Fitch, K.
2006-07-01
The Dynamic Alarm Response Procedure (DARP) system provides a robust, Web-based alternative to existing hard-copy alarm response procedures. This paperless system improves performance by eliminating time wasted looking up paper procedures by number, looking up plant process values and equipment and component status at graphical display or panels, and maintenance of the procedures. Because it is a Web-based system, it is platform independent. DARP's can be served from any Web server that supports CGI scripting, such as Apache{sup R}, IIS{sup R}, TclHTTPD, and others. DARP pages can be viewed in any Web browser that supports Javascript and Scalable Vector Graphicsmore » (SVG), such as Netscape{sup R}, Microsoft Internet Explorer{sup R}, Mozilla Firefox{sup R}, Opera{sup R}, and others. (authors)« less
ERIC Educational Resources Information Center
Hoffman, Jessica A.; Agrawal, Tara; Carter, Sonia; Grinder, AnnMarie; Castaneda-Sceppa, Carmen
2012-01-01
One approach to halting the childhood obesity epidemic has been the modification of foods available to children during the school day. In recent years there has been an increased focus on obesity prevention efforts among children ages birth to 5 and the role of child care settings in prevention efforts. Head Start serves as an important venue for…
A Boltzmann machine for the organization of intelligent machines
NASA Technical Reports Server (NTRS)
Moed, Michael C.; Saridis, George N.
1989-01-01
In the present technological society, there is a major need to build machines that would execute intelligent tasks operating in uncertain environments with minimum interaction with a human operator. Although some designers have built smart robots, utilizing heuristic ideas, there is no systematic approach to design such machines in an engineering manner. Recently, cross-disciplinary research from the fields of computers, systems AI and information theory has served to set the foundations of the emerging area of the design of intelligent machines. Since 1977 Saridis has been developing an approach, defined as Hierarchical Intelligent Control, designed to organize, coordinate and execute anthropomorphic tasks by a machine with minimum interaction with a human operator. This approach utilizes analytical (probabilistic) models to describe and control the various functions of the intelligent machine structured by the intuitively defined principle of Increasing Precision with Decreasing Intelligence (IPDI) (Saridis 1979). This principle, even though resembles the managerial structure of organizational systems (Levis 1988), has been derived on an analytic basis by Saridis (1988). The purpose is to derive analytically a Boltzmann machine suitable for optimal connection of nodes in a neural net (Fahlman, Hinton, Sejnowski, 1985). Then this machine will serve to search for the optimal design of the organization level of an intelligent machine. In order to accomplish this, some mathematical theory of the intelligent machines will be first outlined. Then some definitions of the variables associated with the principle, like machine intelligence, machine knowledge, and precision will be made (Saridis, Valavanis 1988). Then a procedure to establish the Boltzmann machine on an analytic basis will be presented and illustrated by an example in designing the organization level of an Intelligent Machine. A new search technique, the Modified Genetic Algorithm, is presented and proved to converge to the minimum of a cost function. Finally, simulations will show the effectiveness of a variety of search techniques for the intelligent machine.
1998-05-01
Coverage Probability with a Random Optimization Procedure: An Artificial Neural Network Approach by Biing T. Guan, George Z. Gertner, and Alan B...Modeling Training Site Vegetation Coverage Probability with a Random Optimizing Procedure: An Artificial Neural Network Approach 6. AUTHOR(S) Biing...coverage based on past coverage. Approach A literature survey was conducted to identify artificial neural network analysis techniques applicable for
Examining Recall Memory in Infancy and Early Childhood Using the Elicited Imitation Paradigm
Lukowski, Angela F.; Milojevich, Helen M.
2016-01-01
The ability to recall the past allows us to report on details of previous experiences, from the everyday to the significant. Because recall memory is commonly assessed using verbal report paradigms in adults, studying the development of this ability in preverbal infants and children proved challenging. Over the past 30 years, researchers have developed a non-verbal means of assessing recall memory known as the elicited or deferred imitation paradigm. In one variant of the procedure, participants are presented with novel three-dimensional stimuli for a brief baseline period before a researcher demonstrates a series of actions that culminate in an end- or goal-state. The participant is allowed to imitate the demonstrated actions immediately, after a delay, or both. Recall performance is then compared to baseline or to performance on novel control sequences presented at the same session; memory can be assessed for the individual target actions and the order in which they were completed. This procedure is an accepted analogue to the verbal report techniques used with adults, and it has served to establish a solid foundation of the nature of recall memory in infancy and early childhood. In addition, the elicited or deferred imitation procedure has been modified and adapted to answer questions relevant to other aspects of cognitive functioning. The broad utility and application of imitation paradigms is discussed, along with limitations of the approach and directions for future research. PMID:27167994
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wild, M.; Rouhani, S.
1995-02-01
A typical site investigation entails extensive sampling and monitoring. In the past, sampling plans have been designed on purely ad hoc bases, leading to significant expenditures and, in some cases, collection of redundant information. In many instances, sampling costs exceed the true worth of the collected data. The US Environmental Protection Agency (EPA) therefore has advocated the use of geostatistics to provide a logical framework for sampling and analysis of environmental data. Geostatistical methodology uses statistical techniques for the spatial analysis of a variety of earth-related data. The use of geostatistics was developed by the mining industry to estimate oremore » concentrations. The same procedure is effective in quantifying environmental contaminants in soils for risk assessments. Unlike classical statistical techniques, geostatistics offers procedures to incorporate the underlying spatial structure of the investigated field. Sample points spaced close together tend to be more similar than samples spaced further apart. This can guide sampling strategies and determine complex contaminant distributions. Geostatistic techniques can be used to evaluate site conditions on the basis of regular, irregular, random and even spatially biased samples. In most environmental investigations, it is desirable to concentrate sampling in areas of known or suspected contamination. The rigorous mathematical procedures of geostatistics allow for accurate estimates at unsampled locations, potentially reducing sampling requirements. The use of geostatistics serves as a decision-aiding and planning tool and can significantly reduce short-term site assessment costs, long-term sampling and monitoring needs, as well as lead to more accurate and realistic remedial design criteria.« less
ASCCP Colposcopy Standards: How Do We Perform Colposcopy? Implications for Establishing Standards.
Waxman, Alan G; Conageski, Christine; Silver, Michelle I; Tedeschi, Candice; Stier, Elizabeth A; Apgar, Barbara; Huh, Warner K; Wentzensen, Nicolas; Massad, L Stewart; Khan, Michelle J; Mayeaux, Edward J; Einstein, Mark H; Schiffman, Mark H; Guido, Richard S
2017-10-01
The American Society for Colposcopy and Cervical Pathology (ASCCP) Colposcopy Standards recommendations address the role of and approach to colposcopy and biopsy for cervical cancer prevention in the United States. The recommendations were developed by an expert working group appointed by ASCCP's Board of Directors. Working group 3 defined colposcopy procedure guidelines for minimum and comprehensive colposcopy practice and evaluated the use of colposcopy adjuncts. The working group performed a systematic literature review to identify best practices in colposcopy methodology and to evaluate the use of available colposcopy adjuncts. The literature provided little evidence to support specific elements of the procedure. The working group, therefore, implemented a national survey of current and recent ASCCP members to evaluate common elements of the colposcopy examination. The findings of this survey were modified by expert consensus from the ASCCP Colposcopy Standards Committee members to create guidelines for performing colposcopy. The draft recommendations were posted online for public comment and presented at an open session of the International Federation for Cervical Pathology and Colposcopy 2017 World Congress for further comment. All comments were considered in the development of final recommendations. Minimum and comprehensive colposcopy practice guidelines were developed. These guidelines represent recommended practice in all parts of the examination including the following: precolposcopy evaluation, performing the procedure, documentation of findings, biopsy practice, and postprocedure follow-up. These guidelines are intended to serve as a guide to standardize colposcopy across the United States.
Esch, Jesse J; Shah, Pinak B; Cockrill, Barbara A; Farber, Harrison W; Landzberg, Michael J; Mehra, Mandeep R; Mullen, Mary P; Opotowsky, Alexander R; Waxman, Aaron B; Lock, James E; Marshall, Audrey C
2013-04-01
Patients with severe pulmonary arterial hypertension (PAH) face significant morbidity and death as a consequence of progressive right heart failure. Surgical shunt placement between the left PA and descending aorta (Potts shunt) appears promising for PAH palliation in children; however, surgical mortality is likely to be unacceptably high in adults with PAH. We describe a technique for transcatheter Potts shunt (TPS) creation by fluoroscopically guided retrograde needle perforation of the descending aorta at the site of apposition to the left PA to create a tract for deployment of a covered stent between these vessels. This covered stent-anchored by the vessel walls and surrounding tissue-serves as the shunt. TPS creation was considered in 7 patients and performed in 4. The procedure was technically successful in 3 patients; 1 patient died during the procedure as a result of uncontrolled hemothorax. One acute survivor, critically ill at the time of TPS creation, later died of comorbidities. The 2 mid-term survivors (follow-up of 10 and 4 months) are well at home, with symptomatic improvement and no late complications. The 3 candidate patients in whom the procedure was not performed died within 1 month of consideration, underscoring the tenuous nature of this population. TPS creation is feasible and may offer symptomatic relief to select patients with refractory PAH. Further study of this innovative approach is warranted. Copyright © 2013 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.
Duhé, Abby F; Gilmore, L Anne; Burton, Jeffrey H; Martin, Corby K; Redman, Leanne M
2016-07-01
Infant formula is a major source of nutrition for infants, with more than half of all infants in the United States consuming infant formula exclusively or in combination with breast milk. The energy in infant powdered formula is derived from the powder and not the water, making it necessary to develop methods that can accurately estimate the amount of powder used before reconstitution. Our aim was to assess the use of the Remote Food Photography Method to accurately estimate the weight of infant powdered formula before reconstitution among the standard serving sizes. For each serving size (1 scoop, 2 scoops, 3 scoops, and 4 scoops), a set of seven test bottles and photographs were prepared as follow: recommended gram weight of powdered formula of the respective serving size by the manufacturer; three bottles and photographs containing 15%, 10%, and 5% less powdered formula than recommended; and three bottles and photographs containing 5%, 10%, and 15% more powdered formula than recommended (n=28). Ratio estimates of the test photographs as compared to standard photographs were obtained using standard Remote Food Photography Method analysis procedures. The ratio estimates and the US Department of Agriculture data tables were used to generate food and nutrient information to provide the Remote Food Photography Method estimates. Equivalence testing using the two one-sided t tests approach was used to determine equivalence between the actual gram weights and the Remote Food Photography Method estimated weights for all samples, within each serving size, and within underprepared and overprepared bottles. For all bottles, the gram weights estimated by the Remote Food Photography Method were within 5% equivalence bounds with a slight underestimation of 0.05 g (90% CI -0.49 to 0.40; P<0.001) and mean percent error ranging between 0.32% and 1.58% among the four serving sizes. The maximum observed mean error was an overestimation of 1.58% of powdered formula by the Remote Food Photography Method under controlled laboratory conditions, indicating that the Remote Food Photography Method accurately estimated infant powdered formula. Copyright © 2016 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.
Duhé, Abby F.; Gilmore, L. Anne; Burton, Jeffrey H.; Martin, Corby K.; Redman, Leanne M.
2016-01-01
Background Infant formula is a major source of nutrition for infants with over half of all infants in the United States consuming infant formula exclusively or in combination with breast milk. The energy in infant powdered formula is derived from the powder and not the water making it necessary to develop methods that can accurately estimate the amount of powder used prior to reconstitution. Objective To assess the use of the Remote Food Photography Method (RFPM) to accurately estimate the weight of infant powdered formula before reconstitution among the standard serving sizes. Methods For each serving size (1-scoop, 2-scoop, 3-scoop, and 4-scoop), a set of seven test bottles and photographs were prepared including the recommended gram weight of powdered formula of the respective serving size by the manufacturer, three bottles and photographs containing 15%, 10%, and 5% less powdered formula than recommended, and three bottles and photographs containing 5%, 10%, and 15% more powdered formula than recommended (n=28). Ratio estimates of the test photographs as compared to standard photographs were obtained using standard RFPM analysis procedures. The ratio estimates and the United States Department of Agriculture (USDA) data tables were used to generate food and nutrient information to provide the RFPM estimates. Statistical Analyses Performed Equivalence testing using the two one-sided t- test (TOST) approach was used to determine equivalence between the actual gram weights and the RFPM estimated weights for all samples, within each serving size, and within under-prepared and over-prepared bottles. Results For all bottles, the gram weights estimated by the RFPM were within 5% equivalence bounds with a slight under-estimation of 0.05 g (90% CI [−0.49, 0.40]; p<0.001) and mean percent error ranging between 0.32% and 1.58% among the four serving sizes. Conclusion The maximum observed mean error was an overestimation of 1.58% of powdered formula by the RFPM under controlled laboratory conditions indicating that the RFPM accurately estimated infant powdered formula. PMID:26947889
Method for Estimating Patronage of Demand Responsive Transportation Systems
DOT National Transportation Integrated Search
1977-12-01
This study has developed a method for estimating patronage of demand responsive transportation (DRT) systems. This procedure requires as inputs a description of the intended service area, current work trip patterns, characteristics of the served popu...
16 CFR 1502.20 - Authority of presiding officer.
Code of Federal Regulations, 2014 CFR
2014-01-01
... pleadings; (j) Rule on motions and other procedural matters; (k) Rule on motions for summary decision under... determines that no party will be prejudiced, the ends of justice will be served, and the action is in...
16 CFR 1502.20 - Authority of presiding officer.
Code of Federal Regulations, 2011 CFR
2011-01-01
... pleadings; (j) Rule on motions and other procedural matters; (k) Rule on motions for summary decision under... determines that no party will be prejudiced, the ends of justice will be served, and the action is in...
21 CFR 12.70 - Authority of presiding officer.
Code of Federal Regulations, 2010 CFR
2010-04-01
... other procedural matters; (k) Rule on motions for summary decision under § 12.93; (l) Conduct the... party will be prejudiced, the ends of justice will be served, and the action is in accordance with law...
21 CFR 12.70 - Authority of presiding officer.
Code of Federal Regulations, 2013 CFR
2013-04-01
... other procedural matters; (k) Rule on motions for summary decision under § 12.93; (l) Conduct the... party will be prejudiced, the ends of justice will be served, and the action is in accordance with law...
21 CFR 12.70 - Authority of presiding officer.
Code of Federal Regulations, 2014 CFR
2014-04-01
... other procedural matters; (k) Rule on motions for summary decision under § 12.93; (l) Conduct the... party will be prejudiced, the ends of justice will be served, and the action is in accordance with law...
21 CFR 12.70 - Authority of presiding officer.
Code of Federal Regulations, 2012 CFR
2012-04-01
... other procedural matters; (k) Rule on motions for summary decision under § 12.93; (l) Conduct the... party will be prejudiced, the ends of justice will be served, and the action is in accordance with law...
16 CFR 1502.20 - Authority of presiding officer.
Code of Federal Regulations, 2010 CFR
2010-01-01
... pleadings; (j) Rule on motions and other procedural matters; (k) Rule on motions for summary decision under... determines that no party will be prejudiced, the ends of justice will be served, and the action is in...
16 CFR 1502.20 - Authority of presiding officer.
Code of Federal Regulations, 2012 CFR
2012-01-01
... pleadings; (j) Rule on motions and other procedural matters; (k) Rule on motions for summary decision under... determines that no party will be prejudiced, the ends of justice will be served, and the action is in...
ERIC Educational Resources Information Center
Aieta, Joseph F.
1987-01-01
This article illustrates how questions from elementary finance can serve as motivation for studying high order powers, roots, and exponential functions using Logo procedures. A second discussion addresses a relatively unknown algorithm for the trigonometric exponential and hyperbolic functions. (PK)
Use of Laboratory-Supplied Natural Gas in Breakthrough Phenomena.
ERIC Educational Resources Information Center
Eiceman, G. A.; And Others
1985-01-01
Natural gas from regular commercial lines contains enough carbon-8 and above hydrocarbon contaminants to serve as a satisfactory sample for breakthrough experiments. Procedures used, typical results obtained, and theoretical background information are provided. (JN)
Madnani, Nina A; Khan, Kaleem J
2012-01-01
The nail as an anatomic structure protects the terminal phalanx of the digit from injury. Historically, it has served as a tool for protection and for survival. As civilizations developed, it attained the additional function of adornment. Nail beautification is a big industry today, with various nail cosmetics available, ranging from nail hardeners, polishes, extensions, artificial/sculpted nails, and nail decorations. Adverse events may occur either during the nail-grooming procedure or as a reaction to the individual components of the nail cosmetics. This holds true for both the client and the nail technician. Typically, any of the procedures involves several steps and a series of products. Separate "nail-bars" have been set up dedicated to serve women and men interested in nail beautification. This article attempts to comprehensively inform and educate the dermatologist on the services offered, the products used, and the possible/potential adverse effects related to nail-grooming and nail cosmetics.
Zovko, Monika; Kiefer, Markus
2013-02-01
According to classical theories, automatic processes operate independently of attention. Recent evidence, however, shows that masked visuomotor priming, an example of an automatic process, depends on attention to visual form versus semantics. In a continuation of this approach, we probed feature-specific attention within the perceptual domain and tested in two event-related potential (ERP) studies whether masked visuomotor priming in a shape decision task specifically depends on attentional sensitization of visual pathways for shape in contrast to color. Prior to the masked priming procedure, a shape or a color decision task served to induce corresponding task sets. ERP analyses revealed visuomotor priming effects over the occipitoparietal scalp only after the shape, but not after the color induction task. Thus, top-down control coordinates automatic processing streams in congruency with higher-level goals even at a fine-grained level. Copyright © 2012 Society for Psychophysiological Research.
Fedorova, Galina F; Menshov, Valery A; Trofimov, Alexey V; Vasil'ev, Rostislav F
2009-10-01
The general approach disclosed herein opens the new possibilities of exploiting the oxidation processes followed by chemiluminescence (CL) emission for the assessment of an antioxidant potential of natural lipid materials and enables determination of the amount and strength of lipid-borne antioxidants in one experiment. The reliability of the analytical procedure is completely unaffected by an inevitable entering of oxidizable lipid portions into the probe chemiluminescent mixture, which is exemplarily illustrated for the case of vegetable oils which served as sources of antioxidant-containing lipids. As a matter of fact, the difference in the effective radical-scavenging rate constants, determined for the antioxidative constituents of the sunflower and corn oils, perfectly matches the distinction of their qualitative tocopherol contents. In addition to the antiradical activity of lipid samples, the antioxidant potential of the latter may be modified by their influence on hydroperoxide stability, as it has been also demonstrated in the present work.
Lee, Kyung Hwa; Seo, Sang Won; Lim, Tae Sung; Kim, Eun Joo; Kim, Byeong Chae; Kim, Yeshin; Lee, Ho Won; Jeon, Jae Pil; Shim, Sung Mi; Na, Duk L; Huh, Gi Yeong; Lee, Min Cheol; Suh, Yeon Lim
2017-09-01
To obtain an in-depth understanding of brain diseases, including neurodegenerative diseases, psychiatric illnesses, and neoplasms, scientific approach and verification using postmortem human brain tissue with or without disease are essential. Compared to other countries that have run brain banks for decades, South Korea has limited experience with brain banking; nationwide brain banks started only recently. The goal of this study is to provide provisional guidelines for brain autopsy for hospitals and institutes that have not accumulated sufficient expertise. We hope that these provisional guidelines will serve as a useful reference for pathologists and clinicians who are involved and interested in the brain bank system. Also, we anticipate updating the provisional guidelines in the future based on collected data and further experience with the practice of brain autopsy in South Korea. © Copyright: Yonsei University College of Medicine 2017.
van Veldhuizen, Remmers; Delespaul, Philippe; Kroon, Hans; Mulder, Niels
2015-01-01
This article is a response to Nordén and Norlander's 'Absence of Positive Results for Flexible Assertive Community Treatment. What is the next approach?'[1], in which they assert that 'at present [there is] no evidence for Flexible ACT and… that RACT might be able to provide new impulses and new vitality to the treatment mode of ACT'. We question their analyses and conclusions. We clarify Flexible ACT, referring to the Flexible Assertive Community Treatment Manual (van Veldhuizen, 2013) [2] to rectify misconceptions. We discuss Nordén and Norlander's interpretation of research on Flexible ACT. The fact that too little research has been done and that there are insufficient positive results cannot serve as a reason to propagate RACT. However, the Resource Group method does provide inspiration for working with clients to involve their networks more effectively in Flexible ACT.
Industry liaison section implementation plan
NASA Technical Reports Server (NTRS)
Lakowske, Stephen
1990-01-01
The Industry Liaison Section is a new function of the Army/NASA Aircrew-Aircraft Integration (AAAI) Program that is intended to bridge an existing gap between Government developers (including contractors) and outside organizations who are potential users of products and services developed by the AAAI Program. Currently in its sixth year, the Program is experiencing considerable pull from industry and other government organizations to disseminate products. Since the AAAI Program's charter is exploratory and research in nature, and satisfying proper dissemination requirements is in conflict with the rapid prototyping approach utilized by the design team, the AAAI Program has elected to create an Industry Liaison Section (ILS) to serve as the Program's technology transfer focal point. The process by which the ILS may be established, organized and managed is described, including the baseline organizational structure, duties, functions, authority, responsibilities, relations and policies and procedures relevant to the conduct of the ILS.
Improvement of Productivity in TIG Welding Plant by Equipment Design in Orbit
NASA Astrophysics Data System (ADS)
Gnanavel, C.; Saravanan, R.; Chandrasekaran, M.; Jayakanth, J. J.
2017-03-01
Measurements and improvements are very indispensable task at all levels of management. Here some samples are, at operator level: Measuring operating parameters to ensure OEE (Overall Equipment Effectiveness) and measuring Q components performance to ensure quality, at supervisory level: measuring operator’s performance to ensure labour utility at managerial level: production and productivity measurements and at top level capital and capacity utilization. An often accepted statement is “Improvement is impossible without measurement”. Measurements often referred as observation. The case study was conducted at Government Boiler factory in India. The scientific approach followed for indentifying non value added activities. Personalised new equipment designed and installed to achieve productivity improvement of 85% for a day. The new equipment can serve 360o around its axis hence it simplified loading and unloading procedures as well as reduce their times and ensured effective space and time.
Malone, Ruth E; Yerger, Valerie B; McGruder, Carol; Froelicher, Erika
2006-11-01
Community-based participatory research (CBPR) addresses the social justice dimensions of health disparities by engaging marginalized communities, building capacity for action, and encouraging more egalitarian relationships between researchers and communities. CBPR may challenge institutionalized academic practices and the understandings that inform institutional review board deliberations and, indirectly, prioritize particular kinds of research. We present our attempt to study, as part of a CBPR partnership, cigarette sales practices in an inner-city community. We use critical and communitarian perspectives to examine the implications of the refusal of the university institutional review board (in this case, the University of California, San Francisco) to approve the study. CBPR requires expanding ethical discourse beyond the procedural, principle-based approaches common in biomedical research settings. The current ethics culture of academia may sometimes serve to protect institutional power at the expense of community empowerment.
van Veldhuizen, Remmers; Delespaul, Philippe; Kroon, Hans; Mulder, Niels
2015-01-01
This article is a response to Nordén and Norlander’s ‘Absence of Positive Results for Flexible Assertive Community Treatment. What is the next approach?’[1], in which they assert that ‘at present [there is] no evidence for Flexible ACT and… that RACT might be able to provide new impulses and new vitality to the treatment mode of ACT’. We question their analyses and conclusions. We clarify Flexible ACT, referring to the Flexible Assertive Community Treatment Manual (van Veldhuizen, 2013) [2] to rectify misconceptions. We discuss Nordén and Norlander’s interpretation of research on Flexible ACT. The fact that too little research has been done and that there are insufficient positive results cannot serve as a reason to propagate RACT. However, the Resource Group method does provide inspiration for working with clients to involve their networks more effectively in Flexible ACT. PMID:25767558
TURNING IT UPSIDE DOWN: AREAS OF PRESERVED COGNITIVE FUNCTION IN SCHIZOPHRENIA
Gold, James M.; Hahn, Britta; Strauss, Gregory P.; Waltz, James A.
2013-01-01
Patients with schizophrenia demonstrate marked impairments on most clinical neuropsychological tests. These findings suggest that patients suffer from a generalized form of cognitive impairment, with little evidence of spared performance documented in several large meta-analytic reviews of the clinical literature. In contrast, we review evidence for relative sparing of aspects of attention, procedural memory, and emotional processing observed in studies that have employed experimental approaches adapted from the cognitive and affective neuroscience literature. These islands of preserved performance suggest that the cognitive deficits in schizophrenia are not as general as they appear to be when assayed with clinical neuropsychological methods. The apparent contradiction in findings across methods may offer important clues about the nature of cognitive impairment in schizophrenia. The documentation of preserved cognitive function in schizophrenia may serve to sharpen hypotheses about the biological mechanisms that are implicated in the illness. PMID:19452280
Application of the Athlete's Performance Passport for Doping Control: A Case Report.
Iljukov, Sergei; Bermon, Stephane; Schumacher, Yorck O
2018-01-01
The efficient use of testing resources is a key issue in the fight against doping. The longitudinal tracking of sporting performances to identify unusual improvements possibly caused by doping, so-called "athlete's performance passport" (APP) is a new concept to improve targeted anti-doping testing. In fact, unusual performances by an athlete would trigger a more thorough testing program. In the present case report, performance data is modeled using the critical power concept for a group of athletes based on their past performances. By these means, an athlete with unusual deviations from his predicted performances was identified. Subsequent target testing using blood testing and the athlete biological passport resulted in an anti-doping rule violation procedure and suspension of the athlete. This case demonstrates the feasibility of the APP approach where athlete's performance is monitored and might serve as an example for the practical implementation of the method.
Application of the Athlete's Performance Passport for Doping Control: A Case Report
Iljukov, Sergei; Bermon, Stephane; Schumacher, Yorck O.
2018-01-01
The efficient use of testing resources is a key issue in the fight against doping. The longitudinal tracking of sporting performances to identify unusual improvements possibly caused by doping, so-called “athlete's performance passport” (APP) is a new concept to improve targeted anti-doping testing. In fact, unusual performances by an athlete would trigger a more thorough testing program. In the present case report, performance data is modeled using the critical power concept for a group of athletes based on their past performances. By these means, an athlete with unusual deviations from his predicted performances was identified. Subsequent target testing using blood testing and the athlete biological passport resulted in an anti-doping rule violation procedure and suspension of the athlete. This case demonstrates the feasibility of the APP approach where athlete's performance is monitored and might serve as an example for the practical implementation of the method. PMID:29651247
Some aspects of modeling hydrocarbon oxidation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gal, D.; Botar, L.; Danoczy, E.
1981-01-01
A modeling procedure for the study of hydrocarbon oxidation is suggested, and its effectiveness for the oxidation of ethylbenzene is demonstrated. As a first step in modeling, systematization involves compilation of possible mechanisms. Then, by introduction of the concept of kinetic communication, the chaotic set of possible mechanisms is systematized into a network. Experimentation serves both as feedback to the systematic arrangement of information and source of new information. Kinetic treatment of the possible mechanism has been accomplished by two different approaches: by classical inductive calculations starting with a small mechanism and using kinetic approximations, and by computer simulation. Themore » authors have compiled a so-called Main Contributory Mechanism, involving processes - within the possible mechanism - which contribute basically to the formation and consumption of the intermediates, to the consumption of the starting compounds and to the formation of the end products. 24 refs.« less
Casting technology for ODS steels - the internal oxidation approach
NASA Astrophysics Data System (ADS)
Miran, S.; Franke, P.; Möslang, A.; Seifert, H. J.
2017-07-01
The formation of stainless ODS steel by internal oxidation of as-cast steel has been investigated. An alloy (Fe-16Cr-0.2Al-0.05Y, wt.%) was embedded in a (VO/V2O3) powder mixture serving as an oxygen activity buffer and heat treated at 1450 °C for 20 h. After this procedure no oxide scale was present on the surface of the sample but a zone of internal oxidation with a depth of about 2000 μm was formed in its interior. The precipitates within this zone consisted of two types of oxides. Discrete aluminium oxide particles with a size of a few micrometres were formed in outer regions of the specimen. Finer aluminium-yttrium oxides with a size of some hundred nanometres were mainly precipitated in inner regions of the sample. The results can be considered as a promising step towards an alternative production route for ODS steels.
Process improvement program evolves into compliance program at an integrated delivery system.
Tyk, R C; Hylton, P G
1998-09-01
An integrated delivery system discovered questionable practices when it undertook a process-improvement initiative for its revenue-to-cash cycle. These discoveries served as a wake-up call to the organization that it needed to develop a comprehensive corporate compliance program. The organization engaged legal counsel to help it establish such a program. A corporate compliance officer was hired, and a compliance committee was set up. They worked with counsel to develop the structure and substance of the program and establish a corporate code of conduct that became a part of the organization's policies and procedures. Teams were formed in various areas of the organization to review compliance-related activities and suggest improvements. Clinical and nonclinical staff attended mandatory educational sessions about the program. By approaching compliance systematically, the organization has put itself in an excellent position to avoid fraudulent and abusive activities- and the government scrutiny they invite.
Short-Chain Polysaccharide Analysis in Ethanol-Water Solutions.
Yan, Xun
2017-07-01
This study demonstrates that short-chain polysaccharides, or oligosaccharides, could be sufficiently separated with hydrophilic interaction LC (HILIC) conditions and quantified by evaporative light-scattering detection (ELSD). The multianalyte calibration approach improved the efficiency of calibrating the nonlinear detector response. The method allowed easy quantification of short-chain carbohydrates. Using the HILIC method, the oligosaccharide solubility and its profile in water/alcohol solutions at room temperature were able to be quantified. The results showed that the polysaccharide solubility in ethanol-water solutions decreased as ethanol content increased. The results also showed oligosaccharides to have minimal solubility in pure ethanol. In a saturated maltodextrin ethanol (80%) solution, oligosaccharide components with a degree of polymerization >12 were practically insoluble and contributed less than 0.2% to the total solute dry weight. The HILIC-ELSD method allows for the identification and quantification of low-MW carbohydrates individually and served as an alternative method to current gel permeation chromatography procedures.
NASA Astrophysics Data System (ADS)
Mihálka, Zsuzsanna É.; Surján, Péter R.
2017-12-01
The method of analytic continuation is applied to estimate eigenvalues of linear operators from finite order results of perturbation theory even in cases when the latter is divergent. Given a finite number of terms E(k ),k =1 ,2 ,⋯M resulting from a Rayleigh-Schrödinger perturbation calculation, scaling these numbers by μk (μ being the perturbation parameter) we form the sum E (μ ) =∑kμkE(k ) for small μ values for which the finite series is convergent to a certain numerical accuracy. Extrapolating the function E (μ ) to μ =1 yields an estimation of the exact solution of the problem. For divergent series, this procedure may serve as resummation tool provided the perturbation problem has a nonzero radius of convergence. As illustrations, we treat the anharmonic (quartic) oscillator and an example from the many-electron correlation problem.
Preparation, Characterization and Application of Optical Switch Probes.
Petchprayoon, Chutima; Marriott, Gerard
2010-08-01
Optical switches represent a new class of molecular probe with applications in high contrast imaging and optical manipulation of protein interactions. Small molecule, organic optical switches based on nitrospirobenzopyran (NitroBIPS) and their reactive derivatives and conjugates undergo efficient, rapid and reversible, orthogonal optically-driven transitions between a colorless spiro (SP) state and a colored merocyanine (MC) state. The excited MC-state also emits fluorescence, which serves as readout of the state of the switch. Defined optical perturbations of SP and MC generate a defined waveform of MC-fluorescence that can be isolated against unmodulated background signals by using a digital optical lock-in detection approach or to control specific dipolar interactions on proteins. The protocols describe general procedures for the synthesis and spectroscopic characterization of NitroBIPS and specifically labeled conjugates along with methods for the manipulation of dipolar interactions on proteins and imaging of the MC-state of NitroBIPS within living cells.
Patel, Nishant; Chick, Jeffrey Forris Beecham; Gemmete, Joseph J; Castle, Jordan C; Dasika, Narasimham; Saad, Wael E; Srinivasa, Ravi N
2018-05-01
The objective of our study was to report the technique, complications, and clinical outcomes of interventional radiology-operated cholecystoscopy with stone removal for the management of symptomatic cholelithiasis. Ten (77%) men and three (23%) women (mean age, 65 years) with symptomatic cholelithiasis underwent cholecystostomy followed by interventional radiology-operated cholecystoscopy with stone removal. Major comorbidities precluding cholecystectomy included prior cardiac, pulmonary, or abdominal surgery; cirrhosis; sepsis with hyponatremia; seizure disorder; developmental delay; and cholecystoduodenal fistula. Cholecystostomy access, time between cholecystostomy and cholecystoscopy, endoscopic and fragmentation devices used, technical success, procedure time, fluoroscopy time, complications, length of hospital stay, time between cholecystoscopy and cholecystostomy removal, follow-up, and acute cholecystitis recurrence were recorded. Eleven (85%) patients underwent transhepatic cholecystostomy, and two (15%) patients underwent transperitoneal cholecystostomy. The mean time from cholecystostomy to cholecystoscopy was 151 days. Flexible endoscopy was used in eight (62%) patients, rigid endoscopy in three (23%), and both flexible and rigid in two (15%). Electrohydraulic lithotripsy was used in eight procedures, nitinol baskets in seven, ultrasonic lithotripsy in two, and percutaneous thrombectomy devices in one. Primary technical success was achieved in 11 (85%) patients, and secondary technical success was achieved in 13 (100%) patients. The mean procedure time was 164 minutes, and the mean number of procedures required to clear all gallstones was 1. One (8%) patient developed acute pancreatitis, and one (8%) patient died of gastrointestinal hemorrhage. The median hospital length of stay after cholecystoscopy was 1 day for postoperative monitoring. The mean time between cholecystoscopy and cholecystostomy removal was 39 days. One (8%) patient developed recurrent acute cholecystitis 1095 days after cholecystoscopy. Interventional radiology-operated cholecystoscopy may serve as an effective method for percutaneous gallstone removal in patients with multiple comorbidities precluding cholecystectomy.
Hou, Juzhi; Huang, Yongsong; Brodsky, Corynn; Alexandre, Marcelo R; McNichol, Ann P; King, John W; Hu, Feng Sheng; Shen, Ji
2010-09-01
The reliability of chronology is a prerequisite for meaningful paleoclimate reconstructions from sedimentary archives. The conventional approach of radiocarbon dating bulk organic carbon in lake sediments is often hampered by the old carbon effect, i.e., the assimilation of ancient dissolved inorganic carbon (DIC) derived from carbonate bedrocks or other sources. Therefore, radiocarbon dating is ideally performed on organic compounds derived from land plants that use atmospheric CO(2) and rapidly delivered to sediments. We demonstrate that lignin phenols isolated from lake sediments using reversed phase high performance liquid chromatography (HPLC) can serve as effective (14)C dating materials for establishing chronology during the late Quaternary. We developed a procedure to purify lignin phenols, building upon a published method. By isolating lignin from standard wood reference substances, we show that our method yields pure lignin phenols and consistent ages as the consensus ages and that our procedure does not introduce radiocarbon contamination. We further demonstrate that lignin phenol ages are compatible with varve counted and macrofossil dated sediment horizons in Steel Lake and Fayetteville Green Lake. Applying the new method to lake sediment cores from Lake Qinghai demonstrates that lignin phenol ages in Lake Qinghai are consistently younger than bulk total organic carbon (TOC) ages which are contaminated by old carbon effect. We also show that the age offset between lignin and bulk organic carbon differs at different Lake Qinghai sedimentary horizons, suggesting a variable hard water effect at different times and that a uniform age correction throughout the core is inappropriate.
NASA Astrophysics Data System (ADS)
Belfort, Benjamin; Weill, Sylvain; Lehmann, François
2017-07-01
A novel, non-invasive imaging technique is proposed that determines 2D maps of water content in unsaturated porous media. This method directly relates digitally measured intensities to the water content of the porous medium. This method requires the classical image analysis steps, i.e., normalization, filtering, background subtraction, scaling and calibration. The main advantages of this approach are that no calibration experiment is needed, because calibration curve relating water content and reflected light intensities is established during the main monitoring phase of each experiment and that no tracer or dye is injected into the flow tank. The procedure enables effective processing of a large number of photographs and thus produces 2D water content maps at high temporal resolution. A drainage/imbibition experiment in a 2D flow tank with inner dimensions of 40 cm × 14 cm × 6 cm (L × W × D) is carried out to validate the methodology. The accuracy of the proposed approach is assessed using a statistical framework to perform an error analysis and numerical simulations with a state-of-the-art computational code that solves the Richards' equation. Comparison of the cumulative mass leaving and entering the flow tank and water content maps produced by the photographic measurement technique and the numerical simulations demonstrate the efficiency and high accuracy of the proposed method for investigating vadose zone flow processes. Finally, the photometric procedure has been developed expressly for its extension to heterogeneous media. Other processes may be investigated through different laboratory experiments which will serve as benchmark for numerical codes validation.
Pelliccia, Francesco; Trani, Carlo; Biondi-Zoccai, Giuseppe G L; Nazzaro, Marco; Berni, Andrea; Patti, Giuseppe; Patrizi, Roberto; Pironi, Bruno; Mazzarotto, Pietro; Gioffrè, Gaetano; Speciale, Giulio; Pristipino, Christian
2012-09-15
It remains undefined if transradial coronary angiography from a right or left radial arterial approach differs in real-world practice. To address this issue, we performed a subanalysis of the PREVAIL study. The PREVAIL study was a prospective, multicenter, observational survey of unselected consecutive patients undergoing invasive cardiovascular procedures over a 1-month observation period, specifically aimed at assessing the outcomes of radial approach in the contemporary real world. The choice of arterial approach was left to the discretion of the operator. Prespecified end points of this subanalysis were procedural characteristics. Of 1,052 patients consecutively enrolled, 509 patients underwent transradial catheterization, 304 with a right radial and 205 with a left radial approach. Procedural success rates were similar between the 2 groups. Compared to the left radial group, the right radial group had longer procedure duration (46 ± 29 vs 33 ± 24 minutes, p <0.0001) and fluoroscopy time (765 ± 787 vs 533 ± 502, p <0.0001). At multivariate analysis, including a parsimonious propensity score for the choice of left radial approach, duration of procedure (beta coefficient 11.38, p <0.001) and total dose-area product (beta coefficient 11.38, p <0.001) were independently associated with the choice of the left radial artery approach. The operator's proficiency in right/left radial approach did not influence study results. In conclusion, right and left radial approaches are feasible and effective to perform percutaneous procedures. In the contemporary real world, however, the left radial route is associated with shorter procedures and lower radiologic exposure than the right radial approach, independently of an operator's proficiency. Copyright © 2012 Elsevier Inc. All rights reserved.
McMaster, Hope Seib; LeardMann, Cynthia A; Speigle, Steven; Dillman, Don A
2017-04-26
Previous research has found that a "web-push" approach to data collection, which involves contacting people by mail to request an Internet survey response while withholding a paper response option until later in the contact process, consistently achieves lower response rates than a "paper-only" approach, whereby all respondents are contacted and requested to respond by mail. An experiment was designed, as part of the Millennium Cohort Family Study, to compare response rates, sample representativeness, and cost between a web-push and a paper-only approach; each approach comprised 3 stages of mail contacts. The invited sample (n = 4,935) consisted of spouses married to U.S. Service members, who had been serving in the military between 2 and 5 years as of October, 2011. The web-push methodology produced a significantly higher response rate, 32.8% compared to 27.8%. Each of the 3 stages of postal contact significantly contributed to response for both treatments with 87.1% of the web-push responses received over the Internet. The per-respondent cost of the paper-only treatment was almost 40% higher than the web-push treatment group. Analyses revealed no meaningfully significant differences between treatment groups in representation. These results provide evidence that a web-push methodology is more effective and less expensive than a paper-only approach among young military spouses, perhaps due to their heavy reliance on the internet, and we suggest that this approach may be more effective with the general population as they become more uniformly internet savvy.
ERIC Educational Resources Information Center
Nestel, Debra; Kneebone, Roger; Nolan, Carmel; Akhtar, Kash; Darzi, Ara
2011-01-01
Assessment of clinical skills is a critical element of undergraduate medical education. We compare a traditional approach to procedural skills assessment--the Objective Structured Clinical Examination (OSCE) with the Integrated Performance Procedural Instrument (IPPI). In both approaches, students work through "stations" or…
ERIC Educational Resources Information Center
Burnim, Ira A.
This book presents recommended policies and procedural safeguards for programs serving infants, toddlers and their families under Part H of the Education of the Handicapped Act. Policies are presented in five chapters covering: (1) consent to assessment, evaluation and services; (2) notice of parents' rights and of proposed actions; (3) right to…
Use of Metallic Endosseous Implants as a Tooth Substitute.
1979-06-01
exposed in the oral cavity and placed in function with the opposing dentition iBACKGROUND The development of a dental implant that will serve as a...contract year was spent in testing the dental implant as a single tooth replacement. The ultimate goal of this implant study was to develop a free-standing...to read and sign an informed consent form. SURGICAL PROCEDURES The dental implant was inserted into the edentulous area using the exact procedures as
Narouze, Samer N; Provenzano, David; Peng, Philip; Eichenberger, Urs; Lee, Sang Chul; Nicholls, Barry; Moriggl, Bernhard
2012-01-01
The use of ultrasound in pain medicine for interventional axial, nonaxial, and musculoskeletal pain procedures is rapidly evolving and growing. Because of the lack of specialty-specific guidelines for ultrasonography in pain medicine, an international collaborative effort consisting of members of the Special Interest Group on Ultrasonography in Pain Medicine from the American Society of Regional Anesthesia and Pain Medicine, the European Society of Regional Anaesthesia and Pain Therapy, and the Asian Australasian Federation of Pain Societies developed the following recommendations for education and training in ultrasound-guided interventional pain procedures. The purpose of these recommendations is to define the required skills for performing ultrasound-guided pain procedures, the processes for appropriate education, and training and quality improvement. Training algorithms are outlined for practice- and fellowship-based pathways. The previously published American Society of Regional Anesthesia and Pain Medicine and European Society of Regional Anaesthesia and Pain Therapy education and teaching recommendations for ultrasound-guided regional anesthesia served as a foundation for the pain medicine recommendations. Although the decision to grant ultrasound privileges occurs at the institutional level, the committee recommends that the training guidelines outlined in this document serve as the foundation for educational training and the advancement of the practice of ultrasonography in pain medicine.
7 CFR 249.24 - Data safeguarding procedures.
Code of Federal Regulations, 2012 CFR
2012-01-01
... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) Miscellaneous Provisions... authority) that administer food, nutrition, or other assistance programs that serve persons categorically...
7 CFR 249.24 - Data safeguarding procedures.
Code of Federal Regulations, 2014 CFR
2014-01-01
... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) Miscellaneous Provisions... authority) that administer food, nutrition, or other assistance programs that serve persons categorically...
7 CFR 249.24 - Data safeguarding procedures.
Code of Federal Regulations, 2013 CFR
2013-01-01
... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) Miscellaneous Provisions... authority) that administer food, nutrition, or other assistance programs that serve persons categorically...
7 CFR 249.24 - Data safeguarding procedures.
Code of Federal Regulations, 2011 CFR
2011-01-01
... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SENIOR FARMERS' MARKET NUTRITION PROGRAM (SFMNP) Miscellaneous Provisions... authority) that administer food, nutrition, or other assistance programs that serve persons categorically...
78 FR 77354 - Procedural Rules To Permit Parties To File and Serve Documents Electronically
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-23
... by handwriting his or her signature. For documents filed by electronic transmission, a party may sign... transmission. A party or representative of the party shall sign a document by handwriting his signature. (2...
42 CFR 493.1804 - General considerations.
Code of Federal Regulations, 2010 CFR
2010-10-01
...) To protect all individuals served by laboratories against substandard testing of specimens. (2) To safeguard the general public against health and safety hazards that might result from laboratory activities... (CONTINUED) STANDARDS AND CERTIFICATION LABORATORY REQUIREMENTS Enforcement Procedures § 493.1804 General...
Holographic Imaging In Dense Artificial Fog
NASA Technical Reports Server (NTRS)
Liu, Hua-Kuang; Marzwell, Neville
1996-01-01
Artificial fog serves as volume-projection medium for display of three-dimensional image. Projection technique enables display of images for variety of purposes, possibly including entertainment, indoor and outdoor advertising, medical diagnostics and image representations for surgical procedures, and education.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Orendorff, Christopher; Lamb, Joshua; Steele, Leigh Anna Marie
This report describes recommended abuse testing procedures for rechargeable energy storage systems (RESSs) for electric vehicles. This report serves as a revision to the FreedomCAR Electrical Energy Storage System Abuse Test Manual for Electric and Hybrid Electric Vehicle Applications (SAND2005-3123).
NASA Astrophysics Data System (ADS)
Pedersen, G. B. M.
2016-02-01
A new object-oriented approach is developed to classify glaciovolcanic landforms (Procedure A) and their landform elements boundaries (Procedure B). It utilizes the principle that glaciovolcanic edifices are geomorphometrically distinct from lava shields and plains (Pedersen and Grosse, 2014), and the approach is tested on data from Reykjanes Peninsula, Iceland. The outlined procedures utilize slope and profile curvature attribute maps (20 m/pixel) and the classified results are evaluated quantitatively through error matrix maps (Procedure A) and visual inspection (Procedure B). In procedure A, the highest obtained accuracy is 94.1%, but even simple mapping procedures provide good results (> 90% accuracy). Successful classification of glaciovolcanic landform element boundaries (Procedure B) is also achieved and this technique has the potential to delineate the transition from intraglacial to subaerial volcanic activity in orthographic view. This object-oriented approach based on geomorphometry overcomes issues with vegetation cover, which has been typically problematic for classification schemes utilizing spectral data. Furthermore, it handles complex edifice outlines well and is easily incorporated into a GIS environment, where results can be edited or fused with other mapping results. The approach outlined here is designed to map glaciovolcanic edifices within the Icelandic neovolcanic zone but may also be applied to similar subaerial or submarine volcanic settings, where steep volcanic edifices are surrounded by flat plains.
Predicting a future lifetime through Box-Cox transformation.
Yang, Z
1999-09-01
In predicting a future lifetime based on a sample of past lifetimes, the Box-Cox transformation method provides a simple and unified procedure that is shown in this article to meet or often outperform the corresponding frequentist solution in terms of coverage probability and average length of prediction intervals. Kullback-Leibler information and second-order asymptotic expansion are used to justify the Box-Cox procedure. Extensive Monte Carlo simulations are also performed to evaluate the small sample behavior of the procedure. Certain popular lifetime distributions, such as Weibull, inverse Gaussian and Birnbaum-Saunders are served as illustrative examples. One important advantage of the Box-Cox procedure lies in its easy extension to linear model predictions where the exact frequentist solutions are often not available.
[Autoshaping of a button-push response and eye movement in human subjects].
Kimura, H; Fukui, I; Inaki, K
1990-12-01
Two experiments were conducted with human subjects to investigate the similarities and differences between animal and human behaviors under autoshaping procedures. In these experiments, light served as CS, and display on TV served as US. Whether the pushing button response or gazing response to CS could be obtained in human subjects under Pavlovian conditioning procedure was examined. In Experiment 1, uninstructed naive subjects were placed in a room containing a push-button and a TV display. Within the experimental sessions, the push-button was lit for 8 s as CS, and then paired with the display of a soft pornographic program on TV for 10 s. The result indicated that the modeling of pushing button promoted the increase of response probability among the subjects. The trials conducted after the rest period indicated an increase of response probability. In Experiment 2, a 4 cm square translucent panel was lit for 20 s as CS, and then paired with the display of a computer graphic picture on TV for 8 s as US. Some subjects started gazing at the CS for several seconds. These results indicated that some subjects could acquire the gazing response under the autoshaping procedure.
Motor Imagery and Tennis Serve Performance: The External Focus Efficacy
Guillot, Aymeric; Desliens, Simon; Rouyer, Christelle; Rogowski, Isabelle
2013-01-01
There is now ample evidence that motor imagery (MI) contributes to enhance motor performance. Previous research also demonstrated that directing athletes’ attention to the effects of their movements on the environment is more effective than focusing on the action per se. The present study aimed therefore at evaluating whether adopting an external focus during MI contributes to enhance tennis serve performance. Twelve high-level young tennis players were included in a test-retest procedure. The effects of regular training were first evaluated. Then, players were subjected to a MI intervention during which they mentally focused on ball trajectory and specifically visualized the space above the net where the serve can be successfully hit. Serve performance was evaluated during both a validated serve test and a real match. The main results showed a significant increase in accuracy and velocity during the ecological serve test after MI practice, as well as a significant improvement in successful first serves and won points during the match. Present data therefore confirmed the efficacy of MI in combination of physical practice to improve tennis serve performance, and further provided evidence that it is feasible to adopt external attentional focus during MI. Practical applications are discussed. Key Points Motor imagery contributes to enhance tennis serve performance. Data provided evidence of the benefits of adopting an external focus of attention during imagery. Results showed significant improvement in successful first serves and won points during a real match. PMID:24149813
2017-06-01
able. If the autopilot is engaged on the INAV controlling solution side and the CDI source is changed to set up for the approach , the NAV mode...release. Distribution is unlimited. PROOF-OF-CONCEPT PART-TASK TRAINER TO ENHANCE SITUATION AWARENESS FOR INSTRUMENT APPROACH PROCEDURES IN AVIATION...CONCEPT PART-TASK TRAINER TO ENHANCE SITUATION AWARENESS FOR INSTRUMENT APPROACH PROCEDURES IN AVIATION DOMAIN 5. FUNDING NUMBERS 6. AUTHOR(S
Tewari, Satyendra; Sharma, Naveen; Kapoor, Aditya; Syal, Sanjeev Kumar; Kumar, Sudeep; Garg, Naveen; Goel, Pravin K.
2013-01-01
Background With the increasing prevalence of coronary artery disease, percutaneous coronary artery procedures have become even more important. Our study has compared transradial to transfemoral artery approach for coronary procedures in Indian population. Aims and objective Comparison of transradial and transfemoral artery approach for percutaneous coronary procedures. Material & methods 26,238 patients, who underwent percutaneous coronary artery procedures, were divided into two groups depending upon transradial and transfemoral artery approach and compared for the various demographic and clinical characteristics, risk factors profile, vascular access and procedural details. Results 26,238 patients underwent percutaneous coronary procedures at our center. 81% were male and 19% were female. 55.65% and 44.35% procedures were done through transfemoral and transradial approach, respectively. 17,417 (66.38%) coronary angiographies were done, out of which 53.92% were transradial and 46.08% were transfemoral procedures. 8821 (33.62%) Percutaneous Transluminal Coronary Angioplasty (PTCA) were done, out of which 25.46% and 74.54% were done through transradial and transfemoral approach, respectively. Mean fluoroscopy time was 4.40 ± 3.55 min for transradial and 3.30 ± 3.66 min for transfemoral CAG (p < 0.001). For PTCA mean fluoroscopy time was 13.53 ± 2.53 min for transradial and 12.61 ± 9.524 min for transfemoral PTCA (p < 0.001). Minor and major procedure related complications and total duration of hospital stay were lower in transradial as compared to transfemoral group. Conclusion The number of percutaneous transradial procedures have increased significantly with reduced complication rates and comparable success rate to transfemoral approach, along with the additional benefits to patient in terms of patient comfort, preference and reduced cost of health delivery. PMID:23992998
NASA Astrophysics Data System (ADS)
Liu, Chaoqun; Chen, Zhaowei; Wang, Zhenzhen; Li, Wei; Ju, Enguo; Yan, Zhengqing; Liu, Zhen; Ren, Jinsong; Qu, Xiaogang
2016-06-01
As a novel technique, photochemical internalization (PCI) has been employed as a new approach to overcome endo/lysosomal restriction, which is one of the main difficulties in both drug and gene delivery. However, the complicated synthesis procedure (usually requiring the self-assembly of polymers, photosensitizers and cargos) and payload specificity greatly limit its further application. In this paper, we employ a highly fluorescent graphitic hollow carbon nitride nanosphere (GHCNS) to simultaneously serve as a PCI photosensitizer, an imaging agent and a drug carrier. The surface modification of GHCNS with multifunctional polysaccharide hyaluronic acid (HA) endows the system with colloidal stability, biocompatibility and cancer cell targeting ability. After CD44 receptor-mediated endocytosis, the nanosystem is embedded in endo/lysosomal vesicles and HA could be specially degraded by hyaluronidase (Hyal), inducing open pores. In the following, with visible light illumination, GHCNS could produce ROS that effectively induced lipid peroxidation and caused endo/lysosomal membrane break, accelerating the cytoplasmic release of the drug in the targeted and irradiated cells. As a result, significantly increased therapeutic potency and specificity against cancer cells could be achieved.As a novel technique, photochemical internalization (PCI) has been employed as a new approach to overcome endo/lysosomal restriction, which is one of the main difficulties in both drug and gene delivery. However, the complicated synthesis procedure (usually requiring the self-assembly of polymers, photosensitizers and cargos) and payload specificity greatly limit its further application. In this paper, we employ a highly fluorescent graphitic hollow carbon nitride nanosphere (GHCNS) to simultaneously serve as a PCI photosensitizer, an imaging agent and a drug carrier. The surface modification of GHCNS with multifunctional polysaccharide hyaluronic acid (HA) endows the system with colloidal stability, biocompatibility and cancer cell targeting ability. After CD44 receptor-mediated endocytosis, the nanosystem is embedded in endo/lysosomal vesicles and HA could be specially degraded by hyaluronidase (Hyal), inducing open pores. In the following, with visible light illumination, GHCNS could produce ROS that effectively induced lipid peroxidation and caused endo/lysosomal membrane break, accelerating the cytoplasmic release of the drug in the targeted and irradiated cells. As a result, significantly increased therapeutic potency and specificity against cancer cells could be achieved. Electronic supplementary information (ESI) available. See DOI: 10.1039/c5nr07719b
A modal parameter extraction procedure applicable to linear time-invariant dynamic systems
NASA Technical Reports Server (NTRS)
Kurdila, A. J.; Craig, R. R., Jr.
1985-01-01
Modal analysis has emerged as a valuable tool in many phases of the engineering design process. Complex vibration and acoustic problems in new designs can often be remedied through use of the method. Moreover, the technique has been used to enhance the conceptual understanding of structures by serving to verify analytical models. A new modal parameter estimation procedure is presented. The technique is applicable to linear, time-invariant systems and accommodates multiple input excitations. In order to provide a background for the derivation of the method, some modal parameter extraction procedures currently in use are described. Key features implemented in the new technique are elaborated upon.
Medical expert witness litmus.
Jones, James W; McCullough, Laurence B
2012-08-01
Several years ago, Dr G. Breaking was the foremost proponent of a new surgical procedure, which was named after him. At a recent national meeting, he discussed a paper that modified the procedure and criticized the presenter's revisions as dangerous--risking increased paralysis. GB's unedited comments were published last month in the specialty's leading journal. Today, an attorney called the office representing a surgical patient who suffered paralysis after undergoing the modified procedure. GB has unremittingly avoided involvement in litigation. The plaintiff's attorney asks him to serve as an expert witness against the surgeon. What should GB do? Copyright © 2012 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved.
SilMush: A procedure for modeling of the geochemical evolution of silicic magmas and granitic rocks
NASA Astrophysics Data System (ADS)
Hertogen, Jan; Mareels, Joyce
2016-07-01
A boundary layer crystallization modeling program is presented that specifically addresses the chemical fractionation in silicic magma systems and the solidification of plutonic bodies. The model is a Langmuir (1989) type approach and does not invoke crystal settling in high-viscosity silicic melts. The primary aim is to model a granitic rock as a congealed crystal-liquid mush, and to integrate major element and trace element modeling. The procedure allows for some exploratory investigation of the exsolution of H2O-fluids and of the fluid/melt partitioning of trace elements. The procedure is implemented as a collection of subroutines for the MS Excel spreadsheet environment and is coded in the Visual Basic for Applications (VBA) language. To increase the flexibility of the modeling, the procedure is based on discrete numeric process simulation rather than on solution of continuous differential equations. The program is applied to a study of the geochemical variation within and among three granitic units (Senones, Natzwiller, Kagenfels) from the Variscan Northern Vosges Massif, France. The three units cover the compositional range from monzogranite, over syenogranite to alkali-feldspar granite. An extensive set of new major element and trace element data is presented. Special attention is paid to the essential role of accessory minerals in the fractionation of the Rare Earth Elements. The crystallization model is able to reproduce the essential major and trace element variation trends in the data sets of the three separate granitic plutons. The Kagenfels alkali-feldspar leucogranite couples very limited variation in major element composition to a considerable and complex variation of trace elements. The modeling results can serve as a guide for the reconstruction of the emplacement sequence of petrographically distinct units. Although the modeling procedure essentially deals with geochemical fractionation within a single pluton, the modeling results bring up a number of questions about the petrogenetic relationships among parental magmas of nearly coeval granitic units emplaced in close proximity.
When is good, good enough? Methodological pragmatism for sustainable guideline development.
Browman, George P; Somerfield, Mark R; Lyman, Gary H; Brouwers, Melissa C
2015-03-06
Continuous escalation in methodological and procedural rigor for evidence-based processes in guideline development is associated with increasing costs and production delays that threaten sustainability. While health research methodologists are appropriately responsible for promoting increasing rigor in guideline development, guideline sponsors are responsible for funding such processes. This paper acknowledges that other stakeholders in addition to methodologists should be more involved in negotiating trade-offs between methodological procedures and efficiency in guideline production to produce guidelines that are 'good enough' to be trustworthy and affordable under specific circumstances. The argument for reasonable methodological compromise to meet practical circumstances is consistent with current implicit methodological practice. This paper proposes a conceptual tool as a framework to be used by different stakeholders in negotiating, and explicitly reporting, reasonable compromises for trustworthy as well as cost-worthy guidelines. The framework helps fill a transparency gap in how methodological choices in guideline development are made. The principle, 'when good is good enough' can serve as a basis for this approach. The conceptual tool 'Efficiency-Validity Methodological Continuum' acknowledges trade-offs between validity and efficiency in evidence-based guideline development and allows for negotiation, guided by methodologists, of reasonable methodological compromises among stakeholders. Collaboration among guideline stakeholders in the development process is necessary if evidence-based guideline development is to be sustainable.
Implementing a Paid Leave Policy for Graduate Students at UW - Madison: The Student Perspective
NASA Astrophysics Data System (ADS)
Gosnell, Natalie M.
2013-01-01
In 2010 the University of Wisconsin - Madison Astronomy Department developed and implemented a departmental paid leave policy for our graduate students, even though the university lacks a campus-wide policy and cannot provide institutional funding for such programs. This policy includes 12 weeks of paid leave in event of a medical emergency or chronic medical condition, as well as paid parental leave for both male and female graduate research assistants. (The policy in its entirety can be found at http://www.astro.wisc.edu/grad-students/policies-procedures/medical-and-family-leave-policy.) This is the first of two presentations describing our policy implementation using a "bottom-up" approach, beginning with the graduate students. I will present the perspective of the graduate students who led the effort and will discuss the steps we took to put our policy in place, from the conception of the plan to the full implementation. These steps included identifying faculty allies, becoming knowledgeable about university policies and resources, involving department staff, and anticipating procedural and bureaucratic hurdles in order to come up with creative solutions in advance. Although each individual institution and department's path to implementing a similar plan will be unique, we hope the methods used to implement our policy at UW - Madison may serve as an example.
Determination of Dacarbazine Φ-Order Photokinetics, Quantum Yields, and Potential for Actinometry.
Maafi, Mounir; Lee, Lok-Yan
2015-10-01
The characterization of drugs' photodegradation kinetics is more accurately achieved by means of the recently developed Φ-order kinetics than by the zero-, first-, and/or second-order classical treatments. The photodegradation of anti-cancer dacarbazine (DBZ) in ethanol has been investigated and found to obey Φ-order kinetics when subjected to continuous and monochromatic irradiation of various wavelengths. Its photochemical efficiency was proven to be wavelength dependent in the 220-350 nm range, undergoing a 50-fold increase. Albeit this variation was well defined by a sigmoid pattern, the overall photoreactivity of DBZ was proven to depend also on the contributions of reactants and experimental attributes. The usefulness of DBZ to serve as a drug-actinometer has been investigated using the mathematical framework of Φ-order kinetics. It has been shown that DBZ in ethanol can represent a good candidate for reliable actinometry in the range 270-350 nm. A detailed and easy-to-implement procedure has been proposed for DBZ actinometry. This procedure could advantageously be implemented prior to the determination of the photodegradation quantum yields. This approach might be found useful for the development of many drug actinometers as alternatives to quinine hydrochloride. © 2015 Wiley Periodicals, Inc. and the American Pharmacists Association.
Pratap, Kunal; Singh, Vijay Pal
2016-03-01
There is a current need for a change in the attitudes of researchers toward the care and use of experimental animals in India. This could be achieved through improvements in the provision of training, to further the integration of the Three Rs concept into scientific research and into the regulations of the Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA). A survey was performed after participants undertook the Federation of European Laboratory Animal Science Associations (FELASA) Category C-based course on Laboratory Animal Science (in 2013 and 2015). It revealed that the participants subsequently employed, in their future research, the practical and theoretical Three Rs approaches that they had learned. This is of great importance in terms of animal welfare, and also serves to benefit their research outcomes extensively. All the lectures, hands-on practical sessions and supplementary elements of the courses, which also involved the handling of small animals and procedures with live animals, were well appreciated by the participants. Insight into developments in practical handling and welfare procedures, norms, directives, and ethical use of laboratory animals in research, was also provided, through the comparison of results from the 2013 and 2015 post-course surveys. 2016 FRAME.
28 CFR 42.406 - Data and information collection.
Code of Federal Regulations, 2014 CFR
2014-07-01
... Section 42.406 Judicial Administration DEPARTMENT OF JUSTICE NONDISCRIMINATION; EQUAL EMPLOYMENT OPPORTUNITY; POLICIES AND PROCEDURES Coordination of Enforcement of Non-discrimination in Federally Assisted... such services on the basis of prohibited discrimination; (2) The population eligible to be served by...
Functional Communication Training
ERIC Educational Resources Information Center
Durand, V. Mark; Moskowitz, Lauren
2015-01-01
Thirty years ago, the first experimental demonstration was published showing that educators could improve significant challenging behavior in children with disabilities by replacing these behaviors with forms of communication that served the same purpose, a procedure called functional communication training (FCT). Since the publication of that…
24 CFR 570.416 - Hispanic-serving institutions work study program.
Code of Federal Regulations, 2012 CFR
2012-04-01
... to, students with disabilities and students who are Black, American Indian/Alaska Native, Hispanic... establish recruitment procedures that identify eligible economically disadvantaged and minority students... providing assistance to economically disadvantaged and minority students who participate in a work study...
24 CFR 570.416 - Hispanic-serving institutions work study program.
Code of Federal Regulations, 2011 CFR
2011-04-01
... to, students with disabilities and students who are Black, American Indian/Alaska Native, Hispanic... establish recruitment procedures that identify eligible economically disadvantaged and minority students... providing assistance to economically disadvantaged and minority students who participate in a work study...
24 CFR 570.416 - Hispanic-serving institutions work study program.
Code of Federal Regulations, 2013 CFR
2013-04-01
... to, students with disabilities and students who are Black, American Indian/Alaska Native, Hispanic... establish recruitment procedures that identify eligible economically disadvantaged and minority students... providing assistance to economically disadvantaged and minority students who participate in a work study...
24 CFR 570.416 - Hispanic-serving institutions work study program.
Code of Federal Regulations, 2014 CFR
2014-04-01
... to, students with disabilities and students who are Black, American Indian/Alaska Native, Hispanic... establish recruitment procedures that identify eligible economically disadvantaged and minority students... providing assistance to economically disadvantaged and minority students who participate in a work study...
Ability Grouping in Physical Education.
ERIC Educational Resources Information Center
Kneer, Marian E.
1982-01-01
Psychomotor ability differences in students are a result of innate motor ability, fitness, neurologic development, psychology, experience, and students' interests and goals. Models and procedures for serving students with ability differences, in the areas of ability identification, curriculum development, and instruction, are described. (CJ)
Design of Quiet Rotorcraft Approach Trajectories
NASA Technical Reports Server (NTRS)
Padula, Sharon L.; Burley, Casey L.; Boyd, D. Douglas, Jr.; Marcolini, Michael A.
2009-01-01
A optimization procedure for identifying quiet rotorcraft approach trajectories is proposed and demonstrated. The procedure employs a multi-objective genetic algorithm in order to reduce noise and create approach paths that will be acceptable to pilots and passengers. The concept is demonstrated by application to two different helicopters. The optimized paths are compared with one another and to a standard 6-deg approach path. The two demonstration cases validate the optimization procedure but highlight the need for improved noise prediction techniques and for additional rotorcraft acoustic data sets.
[Anatomical strategies of Henle trunk in laparoscopic right hemi-colectomy for right colon cancer].
Feng, Bo; Yan, Xialin; Zhang, Sen; Xue, Pei; He, Zirui; Zheng, Minhua
2017-06-25
The advancement of laparoscopic surgery serves as a trigger for better understanding of the vascular structure at the inferior border of the pancreas, especially Henle trunk. Henle trunk was first found as convergence to superior mesenteric vein (SMV) conjoined by sub-right colon vein (SRCV) and right gastroepiploic vein (RGEV), but decades later, anterior superior pancreatic duodenal vein (ASPDV) was described as another conjoint vein of Henle trunk. These tributaries are the basic elements of Henle trunk in early years' study. A proper surgical procedure for Henle trunk can significantly reduce the complications of radical right hemi-colectomy (Japanese D3 resection and European complete mesocolic excision, CME). There are four variations of Henle trunk according to the colic venous tributaries that consists the anatomic variations in transverse colon posterior space(TRCPS). These variations are like "fingerprint and pattern" of CME. The recognition and extension of the TRCS is the key to the dissection of Henle trunk in laparoscopic right hemi-colectomy. Our medical center proposed four feasible approaches for extension:(1) hybrid medial approach; (2) completely medial approach; (3)completely medial access by "page-turning" approach; (4) completely medial approach along RCV. Mostly, RCV ended in Henle trunk, and completely medial approach along RCV is efficient to identify the Henle trunk in CME. We suggest dissecting the inferior margin of pancreas along SMV in a bottom-to-top fashion, followed by the dissection of middle colic vessels to reveal the root of Henle trunk. And it's better to dissect Henle trunk by branch rather than at its root for safety. Here, we describe the anatomic characters of Henles trunk, the surgical approach and strategies of Henle trunk in laparoscopic surgery.
Procedures for precap visual inspection
NASA Technical Reports Server (NTRS)
1984-01-01
Screening procedures for the final precap visual inspection of microcircuits used in electronic system components are described as an aid in training personnel unfamiliar with microcircuits. Processing techniques used in industry for the manufacture of monolithic and hybrid components are presented and imperfections that may be encountered during this inspection are discussed. Problem areas such as scratches, voids, adhesions, and wire bonding are illustrated by photomicrographs. This guide can serve as an effective tool in training personnel to perform precap visual inspections efficiently and reliably.
NASA Technical Reports Server (NTRS)
Malin, J. T.; Carnes, J. G. (Principal Investigator)
1981-01-01
The U.S. corn and soybeans exploratory experiment is described which consisted of evaluations of two technology components of a production forecasting system: classification procedures (crop labeling and proportion estimation at the level of a sampling unit) and sampling and aggregation procedures. The results from the labeling evaluations indicate that the corn and soybeans labeling procedure works very well in the U.S. corn belt with full season (after tasseling) LANDSAT data. The procedure should be readily adaptable to corn and soybeans labeling required for subsequent exploratory experiments or pilot tests. The machine classification procedures evaluated in this experiment were not effective in improving the proportion estimates. The corn proportions produced by the machine procedures had a large bias when the bias correction was not performed. This bias was caused by the manner in which the machine procedures handled spectrally impure pixels. The simulation test indicated that the weighted aggregation procedure performed quite well. Although further work can be done to improve both the simulation tests and the aggregation procedure, the results of this test show that the procedure should serve as a useful baseline procedure in future exploratory experiments and pilot tests.
Materials and processing approaches for foundry-compatible transient electronics.
Chang, Jan-Kai; Fang, Hui; Bower, Christopher A; Song, Enming; Yu, Xinge; Rogers, John A
2017-07-11
Foundry-based routes to transient silicon electronic devices have the potential to serve as the manufacturing basis for "green" electronic devices, biodegradable implants, hardware secure data storage systems, and unrecoverable remote devices. This article introduces materials and processing approaches that enable state-of-the-art silicon complementary metal-oxide-semiconductor (CMOS) foundries to be leveraged for high-performance, water-soluble forms of electronics. The key elements are ( i ) collections of biodegradable electronic materials (e.g., silicon, tungsten, silicon nitride, silicon dioxide) and device architectures that are compatible with manufacturing procedures currently used in the integrated circuit industry, ( ii ) release schemes and transfer printing methods for integration of multiple ultrathin components formed in this way onto biodegradable polymer substrates, and ( iii ) planarization and metallization techniques to yield interconnected and fully functional systems. Various CMOS devices and circuit elements created in this fashion and detailed measurements of their electrical characteristics highlight the capabilities. Accelerated dissolution studies in aqueous environments reveal the chemical kinetics associated with the underlying transient behaviors. The results demonstrate the technical feasibility for using foundry-based routes to sophisticated forms of transient electronic devices, with functional capabilities and cost structures that could support diverse applications in the biomedical, military, industrial, and consumer industries.
Robotic radical prostatectomy: present and future.
Bianco, Fernando J
2011-10-01
The last 10 years have witnessed unprecedented evolution regarding de surgical removal of the prostate gland. Laparoscopic radical prostatectomy broke the open paradigm and started to generate great excitement and expectations. Shortly however, robot-assisted, laparoscopic - Robotic Surgery - emerged to address a fundamental pitfall of prostate laparoscopic surgery: execution reproducibility. Today, robotic assisted laparoscopic prostatectomy is the most used surgical approach to remove the prostate gland. Consistent advantages of this technique are: a shorter convalescent state, marked decrease in blood loss and in experienced hands, shorter average surgical times. Importantly it served to highlight the importance of outcomes as ultimate judge of a procedure success. The data suggest equivalency in long-term functional and oncological outcomes, while clear advantages in the short run: perioperative outcomes with patient rapid return to productive state. That said, the major challenge for robotic surgeons still remains: establish a paradigm that breaks with the tradition and prevents biased reporting due to technology and marketing enthusiasm, but rather takes a critical approach based in prospective, controlled, randomize clinical trials. If the latter objective is reached, urologic robotic surgeons will deliver counseling based on clinical evidence delivering major progress for our Urology field.
NASA Astrophysics Data System (ADS)
Tian, J.; Krauß, T.; d'Angelo, P.
2017-05-01
Automatic rooftop extraction is one of the most challenging problems in remote sensing image analysis. Classical 2D image processing techniques are expensive due to the high amount of features required to locate buildings. This problem can be avoided when 3D information is available. In this paper, we show how to fuse the spectral and height information of stereo imagery to achieve an efficient and robust rooftop extraction. In the first step, the digital terrain model (DTM) and in turn the normalized digital surface model (nDSM) is generated by using a newly step-edge approach. In the second step, the initial building locations and rooftop boundaries are derived by removing the low-level pixels and high-level pixels with higher probability to be trees and shadows. This boundary is then served as the initial level set function, which is further refined to fit the best possible boundaries through distance regularized level-set curve evolution. During the fitting procedure, the edge-based active contour model is adopted and implemented by using the edges indicators extracted from panchromatic image. The performance of the proposed approach is tested by using the WorldView-2 satellite data captured over Munich.
Materials and processing approaches for foundry-compatible transient electronics
NASA Astrophysics Data System (ADS)
Chang, Jan-Kai; Fang, Hui; Bower, Christopher A.; Song, Enming; Yu, Xinge; Rogers, John A.
2017-07-01
Foundry-based routes to transient silicon electronic devices have the potential to serve as the manufacturing basis for “green” electronic devices, biodegradable implants, hardware secure data storage systems, and unrecoverable remote devices. This article introduces materials and processing approaches that enable state-of-the-art silicon complementary metal-oxide-semiconductor (CMOS) foundries to be leveraged for high-performance, water-soluble forms of electronics. The key elements are (i) collections of biodegradable electronic materials (e.g., silicon, tungsten, silicon nitride, silicon dioxide) and device architectures that are compatible with manufacturing procedures currently used in the integrated circuit industry, (ii) release schemes and transfer printing methods for integration of multiple ultrathin components formed in this way onto biodegradable polymer substrates, and (iii) planarization and metallization techniques to yield interconnected and fully functional systems. Various CMOS devices and circuit elements created in this fashion and detailed measurements of their electrical characteristics highlight the capabilities. Accelerated dissolution studies in aqueous environments reveal the chemical kinetics associated with the underlying transient behaviors. The results demonstrate the technical feasibility for using foundry-based routes to sophisticated forms of transient electronic devices, with functional capabilities and cost structures that could support diverse applications in the biomedical, military, industrial, and consumer industries.
Computational Planning in Facial Surgery.
Zachow, Stefan
2015-10-01
This article reflects the research of the last two decades in computational planning for cranio-maxillofacial surgery. Model-guided and computer-assisted surgery planning has tremendously developed due to ever increasing computational capabilities. Simulators for education, planning, and training of surgery are often compared with flight simulators, where maneuvers are also trained to reduce a possible risk of failure. Meanwhile, digital patient models can be derived from medical image data with astonishing accuracy and thus can serve for model surgery to derive a surgical template model that represents the envisaged result. Computerized surgical planning approaches, however, are often still explorative, meaning that a surgeon tries to find a therapeutic concept based on his or her expertise using computational tools that are mimicking real procedures. Future perspectives of an improved computerized planning may be that surgical objectives will be generated algorithmically by employing mathematical modeling, simulation, and optimization techniques. Planning systems thus act as intelligent decision support systems. However, surgeons can still use the existing tools to vary the proposed approach, but they mainly focus on how to transfer objectives into reality. Such a development may result in a paradigm shift for future surgery planning. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
NASA Astrophysics Data System (ADS)
Wu, Qiang; Liu, Yuanzhang; Liu, Donghai; Zhou, Wanfang
2011-09-01
Floor water inrush represents a geohazard that can pose significant threat to safe operations for instance in coal mines in China and elsewhere. Its occurrence is controlled by many factors, and the processes are often not amenable to mathematical expressions. To evaluate the water inrush risk, the paper proposes the vulnerability index approach by coupling the analytic hierarchy process (AHP) and geographic information system (GIS). The detailed procedures of using this innovative approach are shown in a case study in China (Donghuantuo Coal Mine). The powerful spatial data analysis functions of GIS was used to establish the thematic layer of each of the six factors that control the water inrush, and the contribution weights of each factor was determined with the AHP method. The established AHP evaluation model was used to determine the threshold value for each risk level with a histogram of the water inrush vulnerability index. As a result, the mine area was divided into five regions with different vulnerability levels which served as general guidelines for the mine operations. The prediction results were further corroborated with the actual mining data, and the evaluation result is satisfactory.
Implementation of Satellite Techniques in the Air Transport
NASA Astrophysics Data System (ADS)
Fellner, Andrzej; Jafernik, Henryk
2016-06-01
The article shows process of the implementation satellite systems in Polish aviation which contributed to accomplishment Performance-Based Navigation (PBN) concept. Since 1991 authors have introduced Satellite Navigation Equipment in Polish Air Forces. The studies and researches provide to the Polish Air Force alternative approaches, modernize their navigation and landing systems and achieve compatibility with systems of the North Atlantic Treaty Organization (NATO) and International Civil Aviation Organization (ICAO). Acquired experience, conducted military tests and obtained results enabled to take up work scientifically - research in the environment of the civil aviation. Therefore in 2008 there has been launched cooperation with Polish Air Navigation Services Agency (PANSA). Thanks to cooperation, there have been compiled and fulfilled three fundamental international projects: EGNOS APV MIELEC (EGNOS Introduction in European Eastern Region - APV Mielec), HEDGE (Helicopters Deploy GNSS in Europe), SHERPA (Support ad-Hoc to Eastern Region Pre-operational in GNSS). The successful completion of these projects enabled implementation 21 procedures of the RNAV GNSS final approach at Polish airports, contributing to the implementation of PBN in Poland as well as ICAO resolution A37-11. Results of conducted research which served for the implementation of satellite techniques in the air transport constitute the meaning of this material.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pereira, Keith, E-mail: keithjppereira@gmail.com; Baker, Reginald, E-mail: rbaker@med.miami.edu; Salsamendi, Jason
Transjugular intrahepatic portosystemic shunts (TIPS) have evolved as an effective and durable nonsurgical option in the treatment of portal hypertension (PH). It has been shown to improve survival in decompensated cirrhosis and may also serve as a bridge to liver transplantation. In spite of the technical improvements in the procedure, problems occur with the shunt which jeopardizes effective treatment of the PH. Appropriate management is vital to ensure the longevity of the conduit. Shunt revision techniques include endovascular revision techniques and new shunt creation or, in the appropriate patients, alternative/rescue therapies. The ability of interventional radiologists to restore adequate TIPSmore » function has enormous implications for quality of life with palliation, morbidity/mortality related to variceal bleeding and survival if transplant candidates can live long enough to receive a new liver. As such, it is imperative that these treatment strategies are understood and employed when these patients are encountered. In this review, the restoration of appropriate shunt function using various techniques will be discussed as they apply to a variety of clinical scenarios, based on literature. In addition, illustrative case examples highlighting our experience at an academic tertiary medical center will be included. It is the intent to have this document serve as a concise and informative reference to be used by those who may encounter patients with suboptimal functioning TIPS.« less
Pereira, Keith; Baker, Reginald; Salsamendi, Jason; Doshi, Mehul; Kably, Issam; Bhatia, Shivank
2016-05-01
Transjugular intrahepatic portosystemic shunts (TIPS) have evolved as an effective and durable nonsurgical option in the treatment of portal hypertension (PH). It has been shown to improve survival in decompensated cirrhosis and may also serve as a bridge to liver transplantation. In spite of the technical improvements in the procedure, problems occur with the shunt which jeopardizes effective treatment of the PH. Appropriate management is vital to ensure the longevity of the conduit. Shunt revision techniques include endovascular revision techniques and new shunt creation or, in the appropriate patients, alternative/rescue therapies. The ability of interventional radiologists to restore adequate TIPS function has enormous implications for quality of life with palliation, morbidity/mortality related to variceal bleeding and survival if transplant candidates can live long enough to receive a new liver. As such, it is imperative that these treatment strategies are understood and employed when these patients are encountered. In this review, the restoration of appropriate shunt function using various techniques will be discussed as they apply to a variety of clinical scenarios, based on literature. In addition, illustrative case examples highlighting our experience at an academic tertiary medical center will be included. It is the intent to have this document serve as a concise and informative reference to be used by those who may encounter patients with suboptimal functioning TIPS.
NASA Astrophysics Data System (ADS)
Sundari, I. P.; Mariana, D.; Sjoraida, D. F.
2018-03-01
This study examines the performance of the local representative members in serving and channeling people’s aspiration in Sumedang Regency, Indonesia. How the elected members serve their constituents and how they consider the people’s rights were the questions to be answered in this study. The study used a qualitative approach to get the natural settings in which there are many behaviors and events occurred. This study also uses an institutional theory (institutionalism), because the theory could lead the researchers to find the structure, regulation and institutional procedures which could have a significant impact on a public policy and cannot be ignored in policy analysis. This study found that to carry out their functions as elected representatives, the members of the provincial parliament always make themselves available for the community. In doing so, the members of the provincial parliament, among others, absorb and collect the constituents’ aspiration through regular working visits; accommodate and follow up the aspirations and complaints; morally and politically provide accountability to the constituencies. In addition, to receive complaints coming to the local parliament’s office, public aspiration was also obtained in working visits on a regular basis by the members of local parliament in Sumedang as their own region at recess time. In terms of rights, all the services were conducted to fulfill them. Even so, some people still doubt the veracity of such works.
Troeltzsch, Markus; Messlinger, Karl; Brodine, Brian; Gassling, Volker; Troeltzsch, Matthias
2014-10-01
To investigate the efficacy of conservative dental treatment (occlusal splint and pharmacologic therapy) and invasive therapy (prosthetic restorations) in the treatment of tension-type headache (TTH). The study sample was composed of 70 patients who presented with symptomatic TTH and were assigned to three treatment groups according to their treatment needs. Group A (30 patients): a conservative treatment protocol with a combination of an occlusal splint and analgesic and muscle relaxant medication. Group B (10 patients): invasive prosthodontic procedures. Group C (30 patients): patients who refused any type of treatment but consented to the study served as a control group. Pain quality was measured with the Headache Impact Test (HIT-6). The statistical analysis was performed with the Wilcoxon rank test (P≤.05). Conservative treatment with splints and analgesic medication and invasive treatment by prosthetic rehabilitation relieved the TTH symptoms. The patients who received treatment experienced a significant reduction in their discomfort after 6 months (P≤.01), whereas the patients who refused therapy remained, on average, at the same pain level (P≤.117). In group A, the HIT-6 score was reduced for 26 patients, and in group B for 8 patients. In group C a reduction of HIT-6 scores was observed in 10 patients. Conservative or invasive occlusal adjustments may serve as a useful tool in the treatment of TTH.
Investigation of approach slab and its settlement for roads and bridges.
DOT National Transportation Integrated Search
2014-01-01
Approach slabs serve as a transitional system between an approach road and a bridge. Settlement of bridge approach slabs and their : supporting backfill has been experienced by more than ten Departments of Transportation throughout the United States....
A Predental Career Program in a Postgraduate Institution.
ERIC Educational Resources Information Center
Jensen, Oivind Ekman; Brunette, Phyllis M.
1982-01-01
A program is described that provides potential dental school applicants with realistic exposure to dentistry, in cooperation with undergraduate career counseling offices. High school and college students serve as volunteer assistants in three different functions (instrument sterilization, miscellaneous office procedures, and actual dental…
46 CFR 502.204 - Depositions upon written interrogatories.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 9 2011-10-01 2011-10-01 false Depositions upon written interrogatories. 502.204... PRACTICE AND PROCEDURE Depositions, Written Interrogatories, and Discovery § 502.204 Depositions upon written interrogatories. (a) Serving interrogatories; notice. A party desiring to take the deposition of...
46 CFR 502.204 - Depositions upon written interrogatories.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 9 2010-10-01 2010-10-01 false Depositions upon written interrogatories. 502.204... PRACTICE AND PROCEDURE Depositions, Written Interrogatories, and Discovery § 502.204 Depositions upon written interrogatories. (a) Serving interrogatories; notice. A party desiring to take the deposition of...
Code of Federal Regulations, 2011 CFR
2011-04-01
... 23 Highways 1 2011-04-01 2011-04-01 false Standards. 630.404 Section 630.404 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS PRECONSTRUCTION PROCEDURES Geodetic Markers § 630.404 Standards. (a) Highway purposes may best be served by the establishment...
Strategies for effective roundabout approach speed reduction : final report.
DOT National Transportation Integrated Search
2017-05-01
Appropriate deceleration on approaches to roundabouts is primarily accomplished through the use of applicable geometric design principles; however, traffic control devices (specifically signing and markings on the approach) also serve a vital role in...
Santika, Otte; Fahmida, Umi; Ferguson, Elaine L
2009-01-01
Effective population-specific, food-based complementary feeding recommendations (CFR) are required to combat micronutrient deficiencies. To facilitate their formulation, a modeling approach was recently developed. However, it has not yet been used in practice. This study therefore aimed to use this approach to develop CFR for 9- to 11-mo-old Indonesian infants and to identify nutrients that will likely remain low in their diets. The CFR were developed using a 4-phase approach based on linear and goal programming. Model parameters were defined using dietary data collected in a cross-sectional survey of 9- to 11-mo-old infants (n = 100) living in the Bogor District, West-Java, Indonesia and a market survey of 3 local markets. Results showed theoretical iron requirements could not be achieved using local food sources (highest level achievable, 63% of recommendations) and adequate levels of iron, niacin, zinc, and calcium were difficult to achieve. Fortified foods, meatballs, chicken liver, eggs, tempe-tofu, banana, and spinach were the best local food sources to improve dietary quality. The final CFR were: breast-feed on demand, provide 3 meals/d, of which 1 is a fortified infant cereal; > or = 5 servings/wk of tempe/tofu; > or = 3 servings/wk of animal-source foods, of which 2 servings/wk are chicken liver; vegetables, daily; snacks, 2 times/d, including > or = 2 servings/wk of banana; and > or = 4 servings/wk of fortified-biscuits. Results showed that the approach can be used to objectively formulate population-specific CFR and identify key problem nutrients to strengthen nutrition program planning and policy decisions. Before recommending these CFR, their long-term acceptability, affordability, and effectiveness should be assessed.
Kornowski, R; Fuchs, S; Tio, F O; Pierre, A; Epstein, S E; Leon, M B
1999-12-01
Direct myocardial injection of therapeutic agents has been explored as a new method for myocardial revascularization. The integration of a 3D electromechanical mapping catheter with a retractable injection needle should allow for intramyocardial injection to identified sites, obviating the need for open heart surgery. This study assessed the procedural safety and performance characteristics of a novel guided catheter-based transendocardial injection system. The electromagnetic guidance system was coupled with a retrievable 27G needle for left ventricular endocardial injection. Using this system, we injected, transendocardially, methylene-blue (MB) dye tracer at a volume of 0.1 or 0.2 ml per injection in eight normal pigs. Animals were sacrificed acutely, at 1, 3, and 7 days (two animal in each time). Three animals served as controls. The injections were followed by coronary angiography and echocardiogram to assess possible ventricular or coronary perforation and wall motion abnormalities. CK-MB levels were measured up to 24 hr following the procedure. The animals were sacrificed at the assigned time for gross and histopathology evaluation. A total of 101 injections were made in all regions of the heart except the apex and the mitral valve. No animal died as a result of the mapping or injection procedures. Vital signs did not change relative to baseline after the mapping and injection procedures. CK-MB values did not increase over time and there was no evidence of sustained arrhythmia or hemodynamic compromise. There was no evidence of left ventricular or coronary perforation, global or regional wall motion abnormalities, or hemopericardium. On histologic evaluation, the estimated volume of tissue staining was greater than the volume of the injected MB dye due to dispersion of the injectate in the interstitial and intracellular fluid compartments. It is concluded that using this magnetic guidance catheter-based navigational system, it is feasible and safe to perform the transendocardial injection procedure. Thus, if it is determined that direct intramyocardial injection of drugs is a valid therapeutic strategy, this approach offers a clear advantage over surgically based transepicardial injection procedures. Cathet. Cardiovasc. Intervent. 48:447-453, 1999. Copyright 1999 Wiley-Liss, Inc.
Innovation in neurosurgery: less than IDEAL? A systematic review.
Muskens, I S; Diederen, S J H; Senders, J T; Zamanipoor Najafabadi, A H; van Furth, W R; May, A M; Smith, T R; Bredenoord, A L; Broekman, M L D
2017-10-01
Surgical innovation is different from the introduction of novel pharmaceuticals. To help address this, in 2009 the IDEAL Collaboration (Idea, Development, Exploration, Assessment, Long-term follow-up) introduced the five-stage framework for surgical innovation. To evaluate the framework feasibility for novel neurosurgical procedure introduction, two innovative surgical procedures were examined: the endoscopic endonasal approach for skull base meningiomas (EEMS) and the WovenEndobridge (WEB device) for endovascular treatment of intracranial aneurysms. The published literature on EEMS and WEB devices was systematically reviewed. Identified studies were classified according to the IDEAL framework stage. Next, studies were evaluated for possible categorization according to the IDEAL framework. Five hundred seventy-six papers describing EEMS were identified of which 26 papers were included. No prospective studies were identified, and no studies reported on ethical approval or patient informed consent for the innovative procedure. Therefore, no clinical studies could be categorized according to the IDEAL Framework. For WEB devices, 6229 articles were screened of which 21 were included. In contrast to EEMS, two studies were categorized as 2a and two as 2b. The results of this systematic review demonstrate that both EEMS and WEB devices were not introduced according to the (later developed in the case of EEMS) IDEAL framework. Elements of the framework such as informed consent, ethical approval, and rigorous outcomes reporting are important and could serve to improve the quality of neurosurgical research. Alternative study designs and the use of big data could be useful modifications of the IDEAL framework for innovation in neurosurgery.
Li, Shasha; Liu, Xingang; Zhu, Yulong; Dong, Fengshou; Xu, Jun; Li, Minmin; Zheng, Yongquan
2014-09-05
An effective method for the quantification of fluxapyroxad and its three metabolites in soils, sediment and sludge was developed using ultrahigh performance chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS). Both the extraction and clean-up steps of the QuEChERS procedure were optimised using a chemometric tool, which was expected to facilitate the rapid analysis with minimal procedures. Several operating parameters (MeCN/acetic acid ratio in the extraction solution (i.e., acetic acid percentage), water volume, extraction time, PSA amount, C18 amount, and GCB amount) were investigated using a Plackett-Burman (P-B) screening design. Afterward, the significant factors (acetic acid percentage, water volume, and PSA amount) obtained were optimised using central composite design (CCD) combined with the desirability function (DF) to determine the optimum experimental conditions. The optimised procedure provides high-level linearity for all studied compounds with correlation coefficients ranging between 0.9972 and 0.9999. The detection limits were in the range of 0.1 to 1.0μg/kg and the limits of quantitation (LOQs) were between 0.5 and 3.4μg/kg with relative standard deviations (RSD) between 2.3% and 9.6% (n=6). Therefore, the developed protocol can serve as a simple and sensitive tool for monitoring fluxapyroxad and its three metabolites in soil, sediment and sludge samples. Copyright © 2014 Elsevier B.V. All rights reserved.
The war on drugs in sport: a perspective from the front-line.
Mendoza, John
2002-07-01
Recent international developments have served to solidify the international approach to doping in sport. The development of the World Anti-Doping Agency (WADA) has resulted in new, coordinated efforts to address this important sport issue. An array of new efforts and initiatives has been initiated by the new agency. The Sydney and Salt Lake City Olympics were characterized by intensive efforts to minimize doping. The antidoping environment is evolving rapidly, and several profoundly important developments will take place in the immediate future. To outline the challenges, opportunities, and changing circumstances of the current antidoping environment so that sport medicine practitioners might understand the context in which a variety of new initiatives and approaches will develop. At the same time, to ensure that practitioners understand the importance of appropriately developed and delivered antidoping policies, programs, and procedures, and the need for their harmonization. To ensure that sport medicine practitioners appreciate the need for a comprehensive approach to doping control, i.e., programs that include much more than drug testing. A review of relevant policy documents derived from a variety of sport and antidoping organizations; selected references drawn from MEDLINE; and materials prepared by colleagues drawn from the international antidoping community. The increased global effort to address doping is welcome. It will require that several critical issues be addressed that will test the resolve of all involved.
Code of Federal Regulations, 2010 CFR
2010-10-01
... affirmative defenses or counterclaims, as appropriate. One copy of the answer will be served by the Department... Lands: Interior Office of the Secretary of the Interior DEPARTMENT HEARINGS AND APPEALS PROCEDURES... requirements of a complaint, although no particular form or formality is required. Letter size paper should be...
Code of Federal Regulations, 2010 CFR
2010-07-01
... serve as the focal point for all health promotion program issues and to integrate the activities of the... prevention and cessation, physical fitness, nutrition, stress management, alcohol and drug abuse, and early.... (v) As part of routine physical and dental examinations and at other appropriate times, health care...
24 CFR 26.21 - Written interrogatories.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Written interrogatories. 26.21... Development HEARING PROCEDURES Hearings Before Hearing Officers Discovery § 26.21 Written interrogatories. (a) Service of interrogatories. Any party may serve upon any other party written interrogatories, not to...
ERIC Educational Resources Information Center
Guth, Douglas J.
2018-01-01
Community college students are faced with a variety of complex procedures and decisions, from navigating financial aid applications and lengthy course lists, all the while determining how these immediate choices will serve their long-term educational goals. For many individuals either thinking about community college or already enrolled, these…
Code of Federal Regulations, 2010 CFR
2010-10-01
... FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE Wireless Radio Services Applications and... the rule(s) would not be served or would be frustrated by application to the instant case, and that a... factual circumstances of the instant case, application of the rule(s) would be inequitable, unduly...
NASA Technical Reports Server (NTRS)
Nyiri, L. K.; Toth, G. M.
1976-01-01
Model reactions based on chemical, enzymatic or cellular conversion of D glucose into d gluconic acid are designed to unequivocally define the advantages of microgravity on reaction mechanisms, mass-transfers and separation of organic chemicals and to serve as procedures to test the performance characteristics of space bioprocessing equipment.
32 CFR 2800.4 - General information.
Code of Federal Regulations, 2010 CFR
2010-07-01
... STATES SECURITY PROCEDURES § 2800.4 General information. (a) Staff Security Officer/Top Secret Control... Staff Security Officer will serve as Top Secret Control Officer and Assistant Top Secret Control Officer... responsible for the overall supervision of the Top Secret Control program. They will maintain positive control...
45 CFR 81.114 - Expeditious treatment.
Code of Federal Regulations, 2010 CFR
2010-10-01
... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION PRACTICE AND PROCEDURE FOR... presiding officer are deemed communications on the merits, and are improper except when forwarded from parties to a proceeding and served upon all other parties thereto. Such communications should be in the...
32 CFR 1901.41 - Establishment of appeals structure.
Code of Federal Regulations, 2014 CFR
2014-07-01
... HRPB is the Director, Information Management. The Chair may request interested parties to participate.... The ARP is composed of the Director, Information Management, who serves as its Chair; the Information... of Information Act. Their membership, authority, and rules of procedure are as follows. (b...
32 CFR 1901.41 - Establishment of appeals structure.
Code of Federal Regulations, 2012 CFR
2012-07-01
... HRPB is the Director, Information Management. The Chair may request interested parties to participate.... The ARP is composed of the Director, Information Management, who serves as its Chair; the Information... of Information Act. Their membership, authority, and rules of procedure are as follows. (b...
Observing Community Residences.
ERIC Educational Resources Information Center
Taylor, Steven J.; Bogdan, Robert
The document offers guidelines effectively monitoring the quality of care provided in community residences serving people with disabilities. An initial section offers suggestions on observation and evaluation procedures. The remainder of the document lists possible questions to be asked in 19 areas: location, building and yard, relations with the…
24 CFR 200.227 - Multifamily Participation Review Committee.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Multifamily Participation Review... Requirements Previous Participation Review and Clearance Procedure § 200.227 Multifamily Participation Review Committee. (a) Members. (1) The Director, Office of Lender Activities and Land Sales Registration serves as...
Computerized Financial Reporting Based on GAAP.
ERIC Educational Resources Information Center
Tikkanen, Stan; Liljeberg, Burt
1983-01-01
Describes the statewide computerized system developed in Minnesota following the 1976 enactment of the Uniform Financial Accounting and Reporting Standards (UFARS) law. UFARS includes provisions for an advisory council responsible for recommending accounting and reporting procedures, and seven data processing centers to serve all 560 Minnesota…
Roth, V
1991-01-01
Although the number of students with both learning disability and hearing impairment (LDHI) currently enrolled in secondary and postsecondary programs has not been precisely determined, it is clear that these students are currently receiving inadequate assessment and support in many institutions. The best route for serving these students would seem to be collaborative efforts between deaf educators and learning disabilities specialists, yet serious gaps exist between these two professions in regard to interpretation of laws governing special services, training of professionals, and locations of educational programs. The difficulties of developing collaborative work have been compounded by controversies within each field and the heterogeneity of the populations served by both disciplines. Those interested in creating good LDHI assessments should begin by considering the qualifications needed by those conducting evaluation procedures. The inadequacies of current formal assessment devices for this population need to be recognized; informal procedures, such as teacher observation and curriculum-based assessments, are still some of the best tools available for identification and educational planning.
NASA Technical Reports Server (NTRS)
Bai, Haowei; Atiquzzaman, Mohammed; Ivancic, William
2001-01-01
Currently there are two approaches to provide Quality of Service (QoS) in the next generation Internet: An early one is the Integrated Services (IntServ) with the goal of allowing end-to-end QoS to be provided to applications; the other one is the Differentiated Services (DiffServ) architecture providing QoS in the backbone. In this context, a DiffServ network may be viewed as a network element in the total end-to-end path. The objective of this paper is to investigate the possibility of providing end-to-end QoS when IntServ runs over DiffServ backbone in the next generation Internet. Our results show that the QoS requirements of IntServ applications can be successfully achieved when IntServ traffic is mapped to the DiffServ domain in next generation Internet.
NASA Technical Reports Server (NTRS)
Bai, Haowei; Atiquzzaman, Mohammed; Ivancic, William
2001-01-01
Currently there are two approaches to provide Quality of Service (QoS) in the next generation Internet: An early one is the Integrated Services (IntServ) with the goal of allowing end-to-end QoS to be provided to applications; the other one is the Differentiated Services (DiffServ) architecture providing QoS in the backbone. In this context, a DiffServ network may be viewed as a network element in the total end-to-end path. The objective of this paper is to investigate the possibility of providing end-to-end QoS when IntServ runs over DiffServ backbone in the next generation Internet. Our results show that the QoS requirements of IntServ applications can be successfully achieved when IntServ traffic is mapped to the DiffServ domain in next generation Internet.
Choi, Yeon-Ju; Son, Wonsoo; Park, Ki-Su
2016-01-01
Objective This study used the intradural procedural time to assess the overall technical difficulty involved in surgically clipping an unruptured middle cerebral artery (MCA) aneurysm via a pterional or superciliary approach. The clinical and radiological variables affecting the intradural procedural time were investigated, and the intradural procedural time compared between a superciliary keyhole approach and a pterional approach. Methods During a 5.5-year period, patients with a single MCA aneurysm were enrolled in this retrospective study. The selection criteria for a superciliary keyhole approach included : 1) maximum diameter of the unruptured MCA aneurysm <15 mm, 2) neck diameter of the MCA aneurysm <10 mm, and 3) aneurysm location involving the sphenoidal or horizontal segment of MCA (M1) segment and MCA bifurcation, excluding aneurysms distal to the MCA genu. Meanwhile, the control comparison group included patients with the same selection criteria as for a superciliary approach, yet who preferred a pterional approach to avoid a postoperative facial wound or due to preoperative skin trouble in the supraorbital area. To determine the variables affecting the intradural procedural time, a multiple regression analysis was performed using such data as the patient age and gender, maximum aneurysm diameter, aneurysm neck diameter, and length of the pre-aneurysm M1 segment. In addition, the intradural procedural times were compared between the superciliary and pterional patient groups, along with the other variables. Results A total of 160 patients underwent a superciliary (n=124) or pterional (n=36) approach for an unruptured MCA aneurysm. In the multiple regression analysis, an increase in the diameter of the aneurysm neck (p<0.001) was identified as a statistically significant factor increasing the intradural procedural time. A Pearson correlation analysis also showed a positive correlation (r=0.340) between the neck diameter and the intradural procedural time. When comparing the superciliary and pterional groups, no statistically significant between-group difference was found in terms of the intradural procedural time reflecting the technical difficulty (mean±standard deviation : 29.8±13.0 min versus 27.7±9.6 min). Conclusion A superciliary keyhole approach can be a useful alternative to a pterional approach for an unruptured MCA aneurysm with a maximum diameter <15 mm and neck diameter <10 mm, representing no more of a technical challenge. For both surgical approaches, the technical difficulty increases along with the neck diameter of the MCA aneurysm. PMID:27847568
NASA Astrophysics Data System (ADS)
Razavi, S.; Gupta, H. V.
2014-12-01
Sensitivity analysis (SA) is an important paradigm in the context of Earth System model development and application, and provides a powerful tool that serves several essential functions in modelling practice, including 1) Uncertainty Apportionment - attribution of total uncertainty to different uncertainty sources, 2) Assessment of Similarity - diagnostic testing and evaluation of similarities between the functioning of the model and the real system, 3) Factor and Model Reduction - identification of non-influential factors and/or insensitive components of model structure, and 4) Factor Interdependence - investigation of the nature and strength of interactions between the factors, and the degree to which factors intensify, cancel, or compensate for the effects of each other. A variety of sensitivity analysis approaches have been proposed, each of which formally characterizes a different "intuitive" understanding of what is meant by the "sensitivity" of one or more model responses to its dependent factors (such as model parameters or forcings). These approaches are based on different philosophies and theoretical definitions of sensitivity, and range from simple local derivatives and one-factor-at-a-time procedures to rigorous variance-based (Sobol-type) approaches. In general, each approach focuses on, and identifies, different features and properties of the model response and may therefore lead to different (even conflicting) conclusions about the underlying sensitivity. This presentation revisits the theoretical basis for sensitivity analysis, and critically evaluates existing approaches so as to demonstrate their flaws and shortcomings. With this background, we discuss several important properties of response surfaces that are associated with the understanding and interpretation of sensitivity. Finally, a new approach towards global sensitivity assessment is developed that is consistent with important properties of Earth System model response surfaces.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Suzuoka, Daiki; Takahashi, Hideaki, E-mail: hideaki@m.tohoku.ac.jp; Morita, Akihiro
2014-04-07
We developed a perturbation approach to compute solvation free energy Δμ within the framework of QM (quantum mechanical)/MM (molecular mechanical) method combined with a theory of energy representation (QM/MM-ER). The energy shift η of the whole system due to the electronic polarization of the solute is evaluated using the second-order perturbation theory (PT2), where the electric field formed by surrounding solvent molecules is treated as the perturbation to the electronic Hamiltonian of the isolated solute. The point of our approach is that the energy shift η, thus obtained, is to be adopted for a novel energy coordinate of the distributionmore » functions which serve as fundamental variables in the free energy functional developed in our previous work. The most time-consuming part in the QM/MM-ER simulation can be, thus, avoided without serious loss of accuracy. For our benchmark set of molecules, it is demonstrated that the PT2 approach coupled with QM/MM-ER gives hydration free energies in excellent agreements with those given by the conventional method utilizing the Kohn-Sham SCF procedure except for a few molecules in the benchmark set. A variant of the approach is also proposed to deal with such difficulties associated with the problematic systems. The present approach is also advantageous to parallel implementations. We examined the parallel efficiency of our PT2 code on multi-core processors and found that the speedup increases almost linearly with respect to the number of cores. Thus, it was demonstrated that QM/MM-ER coupled with PT2 deserves practical applications to systems of interest.« less
Ethics in American health 1: ethical approaches to health policy.
Ruger, Jennifer Prah
2008-10-01
I trace the evolution of ethical approaches to health policy in the United States and examine a number of critical unresolved issues pertaining to the current set of frameworks. Several themes emerge. First, fair procedures claim more attention than substantive and procedural principles. Second, in the case of public deliberation, more focus has been placed on factors such as procedural mechanisms than on understanding how individuals and groups value different aspects of health and agree on health-related decisions. Third, the nation needs workable frameworks to guide collective choices about valuable social ends and their trade-offs; purely procedural strategies are limited in illuminating overarching health policy and ethics questions. There is a need to integrate consequential and procedural approaches to health ethics and policy.
Reconditioning of Batteries on the International Space Station
NASA Technical Reports Server (NTRS)
Hajela, Gyan; Cohen, Fred; Dalton, Penni
2004-01-01
Primary source of electric power for the International Space Station (ISS) is the photovoltaic module (PVM). At assembly complete stage, the ISS will be served by 4 PVMs. Each PVM contains two independent power channels such that one failure will result in loss of only one power channel. During early stages of assembly, the ISS is served by only one PVM designated as P6. Solar arrays are used to convert solar flux into electrical power. Nickel hydrogen batteries are used to store electrical power for use during periods when the solar input is not adequate to support channel loads. Batteries are operated per established procedures that ensure that they are maintained within specified temperature limits, charge current is controlled to conform to a specified charge profile, and battery voltages are maintained within specified limits. Both power channels on the PVM P6 have been operating flawlessly since December 2000 with 100 percent power availability. All components, including batteries, are monitored regularly to ensure that they are operating within specified limits and to trend their wear out and age effects. The paper briefly describes the battery trend data. Batteries have started to show some effects of aging and a battery reconditioning procedure is being evaluated at this time. Reconditioning is expected to reduce cell voltage divergence and provide data that can be used to update the state of charge (SOC) computation in the software to account for battery age. During reconditioning, each battery, one at a time, will be discharged per a specified procedure and then returned to a full state of charge. The paper describes the reconditioning procedure and the expected benefits. The reconditioning procedures have been thoroughly coordinated by all affected technical teams and approved by all required boards. The reconditioning is tentatively scheduled for September 2004.
Code of Federal Regulations, 2010 CFR
2010-01-01
... should not serve any one meat alternate or form of meat (for example, ground, diced, pieces) more than..., children in kindergarten through grade six are offered vegetables/fruits in minimum daily servings plus an...
Decolonizing Hispanic-Serving Institutions: A Framework for Organizing
ERIC Educational Resources Information Center
Garcia, Gina Ann
2018-01-01
Hispanic-serving institutions (HSIs) should realign their organizational approach in order to liberate themselves and their students. As colonized institutions enrolling colonized people, HSIs must recognize their history of colonialism before moving toward an organizational model grounded in decolonization. "The Organizational Framework for…
A framework for assessing the adequacy and effectiveness of software development methodologies
NASA Technical Reports Server (NTRS)
Arthur, James D.; Nance, Richard E.
1990-01-01
Tools, techniques, environments, and methodologies dominate the software engineering literature, but relatively little research in the evaluation of methodologies is evident. This work reports an initial attempt to develop a procedural approach to evaluating software development methodologies. Prominent in this approach are: (1) an explication of the role of a methodology in the software development process; (2) the development of a procedure based on linkages among objectives, principles, and attributes; and (3) the establishment of a basis for reduction of the subjective nature of the evaluation through the introduction of properties. An application of the evaluation procedure to two Navy methodologies has provided consistent results that demonstrate the utility and versatility of the evaluation procedure. Current research efforts focus on the continued refinement of the evaluation procedure through the identification and integration of product quality indicators reflective of attribute presence, and the validation of metrics supporting the measure of those indicators. The consequent refinement of the evaluation procedure offers promise of a flexible approach that admits to change as the field of knowledge matures. In conclusion, the procedural approach presented in this paper represents a promising path toward the end goal of objectively evaluating software engineering methodologies.
78 FR 33265 - Proposed Establishment of Class E Airspace; Umatilla, FL
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-04
...) Global Positioning System (GPS) Standard Instrument Approach Procedures at Umatilla Municipal Airport... (GPS) standard instrument approach procedures for Umatilla Municipal Airport. Controlled airspace...
Surrogate decision making: do we have to trade off accuracy and procedural satisfaction?
Frey, Renato; Hertwig, Ralph; Herzog, Stefan M
2014-02-01
Making surrogate decisions on behalf of incapacitated patients can raise difficult questions for relatives, physicians, and society. Previous research has focused on the accuracy of surrogate decisions (i.e., the proportion of correctly inferred preferences). Less attention has been paid to the procedural satisfaction that patients' surrogates and patients attribute to specific approaches to making surrogate decisions. The objective was to investigate hypothetical patients' and surrogates' procedural satisfaction with specific approaches to making surrogate decisions and whether implementing these preferences would lead to tradeoffs between procedural satisfaction and accuracy. Study 1 investigated procedural satisfaction by assigning participants (618 in a mixed-age but relatively young online sample and 50 in an older offline sample) to the roles of hypothetical surrogates or patients. Study 2 (involving 64 real multigenerational families with a total of 253 participants) investigated accuracy using 24 medical scenarios. Hypothetical patients and surrogates had closely aligned preferences: Procedural satisfaction was highest with a patient-designated surrogate, followed by shared surrogate decision-making approaches and legally assigned surrogates. These approaches did not differ substantially in accuracy. Limitations are that participants' preferences regarding existing and novel approaches to making surrogate decisions can only be elicited under hypothetical conditions. Next to decision making by patient-designated surrogates, shared surrogate decision making is the preferred approach among patients and surrogates alike. This approach appears to impose no tradeoff between procedural satisfaction and accuracy. Therefore, shared decision making should be further studied in representative samples of the general population, and if people's preferences prove to be robust, they deserve to be weighted more strongly in legal frameworks in addition to patient-designated surrogates.
Support for the Development of Technological Innovations: Promoting Responsible Social Uses.
Legault, Georges A; Verchère, Céline; Patenaude, Johane
2018-04-01
How can technological development, economic development, and the claims from society be reconciled? How should responsible innovation be promoted? The "responsible social uses" approach proposed here was devised with these considerations in view. In this article, a support procedure for promoting responsible social uses (RSU) is set out and presented. First, the context in which this procedure emerged, which incorporates features of both the user-experience approach and that of ethical acceptability in technological development, is specified. Next, the characteristic features of the procedure are presented, that is, its purpose, fundamental orientation, and component parts as experimented by partners. Third, the RSU approach is compared with other support approaches and considered in term of how each approach assumes responsible innovation. Briefly, the RSU procedure is a way of addressing the issue of responsible innovation through an effective integration of social concerns.
Outcomes of transcatheter aortic valve replacement using a minimalist approach.
Gurevich, Sergey; Oestreich, Brett; Kelly, Rosemary F; Mbai, Mackenzie; Bertog, Stefan; Ringsred, Karen; Lawton, Annette; Thooft, Brenda; Wagner, Julie; Garcia, Santiago
2018-03-01
Transcatheter Aortic Valve Replacement (TAVR) is increasingly performed using a minimalist approach under monitored anesthesia care (MAC). The safety of this approach remains controversial and adoption has been low in the US. The study cohort was comprised of 130 patients (98% male) who underwent TAVR between 4/2015 and 4/2017 at the Minneapolis VA. We compared the outcomes of 81 patients who underwent TAVR using a standard approach (standard TAVR) and 49 who underwent TAVR using a minimalist approach (minimalist TAVR). Outcome measures included device and procedural success, procedural efficiency, length of intensive care unit (ICU) and hospital stay, procedural complications and hospital readmissions. Mean age was 80 (±9) years and median (IQR) STS score was 5 (4-6). Access included transfemoral (n = 111, 85%) and alternative (n = 19, 15%). Minimalist TAVR was associated with reduced procedural time: median 101 min (IQR: 78-135) versus 127 min (IQR: 97-182, p = 0.03), fluoroscopy time: median 18 min (IQR: 12-26) versus 24 min (IQR: 16-38), p = 0.001), contrast volume 90 ml (IQR: 70-120 ml) versus 140 ml (IQR: 86-213 ml, p < 0.001). A minimalistic approach to TAVR is associated with improved procedural efficiency and reduced length of stay without compromising procedural success or clinical outcomes. Published by Elsevier Inc.
Resource Document for the Design of Electronic Instrument Approach Procedure Displays
DOT National Transportation Integrated Search
1995-03-01
Instrument approach procedure (IAP) charts play a large role in contributing to the success or failure of approaches and : landings. Paper IAP charts have been criticized for excessive clutter, for text sizes that are too small to read, and : for ina...
DOT National Transportation Integrated Search
1992-02-01
Instrument approach procedure (IAP) charts are often cluttered and confusing. The quantified effects of chart design : changes on information transfer are needed by chart manufacturers to make changes uhich will enhance information transfer : and hum...
Procedures for Selecting Items for Computerized Adaptive Tests.
ERIC Educational Resources Information Center
Kingsbury, G. Gage; Zara, Anthony R.
1989-01-01
Several classical approaches and alternative approaches to item selection for computerized adaptive testing (CAT) are reviewed and compared. The study also describes procedures for constrained CAT that may be added to classical item selection approaches to allow them to be used for applied testing. (TJH)
Interpretive Management: What General Managers Can Learn from Design.
ERIC Educational Resources Information Center
Lester, Richard K.; Piore, Michael J.; Malek, Kamal M.
1998-01-01
An analytical management approach reflects a traditional perspective and an interpretive approach involves a perspective suited to rapidly changing, unpredictable markets. Both approaches are valid, but each serves different purposes and calls for different strategies and skills. (JOW)
76 FR 60706 - Practices and Procedures
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-30
... publication of nonprecedential Orders will serve the goal of openness in the Board's decision-making by giving... that the Board may issue a final decision and, when appropriate, order a date for compliance with that decision. The Board received comments concerning this interim rule from two individuals. The first...
43 CFR 2450.4 - Protests: Initial classification decision.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Protests: Initial classification decision... CLASSIFICATION SYSTEM Petition-Application Procedures § 2450.4 Protests: Initial classification decision. (a) For a period of 30 days after the proposed classification decision has been served upon the parties...
Code of Federal Regulations, 2013 CFR
2013-07-01
... AND COMMAND SPONSORED FAMILY MEMBERS § 589.2 Policy. (a) This part (chapter) implements procedural... well as to their command sponsored family members. (b) DODD 5525.9 requires DoD cooperation with courts... DoD employees serving outside the United States, as well as their command sponsored family members...
Code of Federal Regulations, 2012 CFR
2012-07-01
... AND COMMAND SPONSORED FAMILY MEMBERS § 589.2 Policy. (a) This part (chapter) implements procedural... well as to their command sponsored family members. (b) DODD 5525.9 requires DoD cooperation with courts... DoD employees serving outside the United States, as well as their command sponsored family members...
Code of Federal Regulations, 2014 CFR
2014-07-01
... AND COMMAND SPONSORED FAMILY MEMBERS § 589.2 Policy. (a) This part (chapter) implements procedural... well as to their command sponsored family members. (b) DODD 5525.9 requires DoD cooperation with courts... DoD employees serving outside the United States, as well as their command sponsored family members...
Code of Federal Regulations, 2012 CFR
2012-07-01
.... (i) No person because of race, color, creed, sex, age, disability, or national origin shall be... that serve as the legal basis for the creation of Boy Scouts organizations (including Boy Scouts, Cub... Boy Scouts or their official affiliates; Boy Scouts activities on DoD installations; or sponsorship of...
Code of Federal Regulations, 2014 CFR
2014-07-01
.... (i) No person because of race, color, creed, sex, age, disability, or national origin shall be... that serve as the legal basis for the creation of Boy Scouts organizations (including Boy Scouts, Cub... Boy Scouts or their official affiliates; Boy Scouts activities on DoD installations; or sponsorship of...
Code of Federal Regulations, 2013 CFR
2013-07-01
.... (i) No person because of race, color, creed, sex, age, disability, or national origin shall be... that serve as the legal basis for the creation of Boy Scouts organizations (including Boy Scouts, Cub... Boy Scouts or their official affiliates; Boy Scouts activities on DoD installations; or sponsorship of...
Code of Federal Regulations, 2011 CFR
2011-07-01
.... (i) No person because of race, color, creed, sex, age, disability, or national origin shall be... that serve as the legal basis for the creation of Boy Scouts organizations (including Boy Scouts, Cub... Boy Scouts or their official affiliates; Boy Scouts activities on DoD installations; or sponsorship of...
Code of Federal Regulations, 2010 CFR
2010-07-01
.... (i) No person because of race, color, creed, sex, age, disability, or national origin shall be... that serve as the legal basis for the creation of Boy Scouts organizations (including Boy Scouts, Cub... Boy Scouts or their official affiliates; Boy Scouts activities on DoD installations; or sponsorship of...
34 CFR 303.23 - Service coordination (case management).
Code of Federal Regulations, 2011 CFR
2011-07-01
... appropriate services and situations necessary to benefit the development of each child being served for the... INFANTS AND TODDLERS WITH DISABILITIES General Purpose, Eligibility, and Other General Provisions § 303.23... child eligible under this part and the child's family to receive the rights, procedural safeguards, and...
34 CFR 303.23 - Service coordination (case management).
Code of Federal Regulations, 2010 CFR
2010-07-01
... appropriate services and situations necessary to benefit the development of each child being served for the... INFANTS AND TODDLERS WITH DISABILITIES General Purpose, Eligibility, and Other General Provisions § 303.23... child eligible under this part and the child's family to receive the rights, procedural safeguards, and...
STANDARD EVALUATION PROCEDURES FOR SUBMITTED DEVELOPMENTAL NEUROTOXICITY DATA
As a NAFTA-inspired multi-governmental initiative, experts from the US EPA (Office of Research and Development, Office of Pesticide Program, or OPP) and the PMRA (Pest Management Regulatory Agency) of Health Canada formed a working group to create a document that would serve as a...
Serving Students with or At-Risk for Emotional and Behavior Disorders: Future Challenges.
ERIC Educational Resources Information Center
Lane, Kathleen Lynne L.; Gresham, Frank M.; O'Shaughnessy, Tam E.
2002-01-01
Four challenges in the emotional/behavioral disorders field are discussed: implementation of empirically validated screening procedures; better understanding of the curriculum and instruction currently used to educate students with emotional disturbances; investigation of the relationship between underachievement and externalizing behaviors; and…
Code of Federal Regulations, 2010 CFR
2010-01-01
... PROCEEDINGS UNDER RESEARCH, PROMOTION, AND INFORMATION PROGRAMS Rules of Practice and Procedure Governing... interest in the outcome of a proceeding shall serve as judge in such proceeding. (b) Power of judge... shall have power to: (1) Rule upon motions and requests; (2) Change the time and place of hearings, and...
77 FR 39572 - Assessment of Mediation and Arbitration Procedures
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-03
... making changes to the Board's existing rules and establishing new rules. The Board also sought input.... SUMMARY: In a decision served on March 28, 2012, the Surface Transportation Board (Board) proposed... hearing time to call attention to the points they believe are particularly important. Witnesses should...
5 CFR 1216.204 - Service of requests or demands.
Code of Federal Regulations, 2010 CFR
2010-01-01
... Section 1216.204 Administrative Personnel MERIT SYSTEMS PROTECTION BOARD ORGANIZATION AND PROCEDURES TESTIMONY BY MSPB EMPLOYEES RELATING TO OFFICIAL INFORMATION AND PRODUCTION OF OFFICIAL RECORDS IN LEGAL... served on the Clerk of the Board, U.S. Merit Systems Protection Board, 1615 M Street, NW., Washington, DC...
Sense of Justice in School and Civic Attitudes
ERIC Educational Resources Information Center
Resh, Nura; Sabbagh, Clara
2014-01-01
Contending that justice experiences in school serve as a hidden curriculum that conveys messages about the wider society and impact student attitudes and behavior, we investigate the effects of students' sense of distributive and (school) procedural justice on democratic-related attitudes: liberal democratic orientation (civil rights), social…
32 CFR 231.8 - Procedures-overseas credit unions.
Code of Federal Regulations, 2012 CFR
2012-07-01
... geographic franchise. (2) The extension of credit union service overseas is encouraged consistent with the... geographic franchise with a specific field of membership, the Secretary of the Military Department (or... geographic franchises assigned to credit unions serving DoD overseas installations. (ii) Where there is no Do...
32 CFR 231.8 - Procedures-overseas credit unions.
Code of Federal Regulations, 2010 CFR
2010-07-01
... geographic franchise. (2) The extension of credit union service overseas is encouraged consistent with the... geographic franchise with a specific field of membership, the Secretary of the Military Department (or... geographic franchises assigned to credit unions serving DoD overseas installations. (ii) Where there is no Do...
32 CFR 231.8 - Procedures-overseas credit unions.
Code of Federal Regulations, 2013 CFR
2013-07-01
... geographic franchise. (2) The extension of credit union service overseas is encouraged consistent with the... geographic franchise with a specific field of membership, the Secretary of the Military Department (or... geographic franchises assigned to credit unions serving DoD overseas installations. (ii) Where there is no Do...
32 CFR 231.8 - Procedures-overseas credit unions.
Code of Federal Regulations, 2014 CFR
2014-07-01
... geographic franchise. (2) The extension of credit union service overseas is encouraged consistent with the... geographic franchise with a specific field of membership, the Secretary of the Military Department (or... geographic franchises assigned to credit unions serving DoD overseas installations. (ii) Where there is no Do...
32 CFR 231.8 - Procedures-overseas credit unions.
Code of Federal Regulations, 2011 CFR
2011-07-01
... geographic franchise. (2) The extension of credit union service overseas is encouraged consistent with the... geographic franchise with a specific field of membership, the Secretary of the Military Department (or... geographic franchises assigned to credit unions serving DoD overseas installations. (ii) Where there is no Do...
Surfing Global Change: Negotiating Sustainable Solutions
ERIC Educational Resources Information Center
Ahamer, Gilbert
2006-01-01
SURFING GLOBAL CHANGE (SGC) serves as a procedural shell for attaining sustainable solutions for any interdisciplinary issue and is intended for use in advanced university courses. The participants' activities evolve through five levels from individual argumentation to molding one's own views for the "common good." The paradigm of…
77 FR 33663 - Practices and Procedures
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-07
... some jurisdictional elements may be established by making nonfrivolous allegations. The U.S. Court of... date on which documents are served'') and unclear, since ``service'' is defined as the ``process of... agency need not prove the elements of its case, and the appellant may not raise other affirmative...
Code of Federal Regulations, 2011 CFR
2011-04-01
... PROCEDURES Hearings Before Hearing Officers Pleadings and Motions § 26.13 Complaint. (a) Respondent. A complaint shall be served upon the party against whom an administrative action is taken, who shall be called... administrative action is based. The grounds set forth in the complaint may not contain allegations beyond the...
29 CFR 1978.114 - District court jurisdiction of retaliation complaints under STAA.
Code of Federal Regulations, 2011 CFR
2011-07-01
..., and the Associate Solicitor for Occupational Safety and Health. The complainant must file and serve a... STAA. 1978.114 Section 1978.114 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF RETALIATION...
Financial Management in the Strategic Systems Project Office.
SSPO, the largest program office in the Navy and in existence for over 20 years, has perfected time tested financial management procedures which may...serve as a model for the student of program management. This report presents an overview of the SSPO financial management concepts and general
Discretionary Grants Administration Manual.
ERIC Educational Resources Information Center
Office of Human Development Services (DHHS), Washington, DC.
This manual sets forth applicable administrative policies and procedures to recipients of discretionary project grants or cooperative agreements awarded by program offices in the Office of Human Development Services (HDS). It is intended to serve as a basic reference for project directors and business officers of recipient organizations who are…
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-05
... interested persons about important policies, procedures, and registration related decisions, and serve to...: Richard P. Dumas, Pesticide Re- evaluation Division, Office of Pesticide Programs, Environmental... applicability of this action to a particular entity, consult the person listed under FOR FURTHER INFORMATION...
Code of Federal Regulations, 2010 CFR
2010-04-01
... PROCEDURES Geodetic Markers § 630.404 Standards. (a) Highway purposes may best be served by the establishment... than one kilometer. These requirements may be waived only with the approval of the Administrator. (b... permanent points, preferably within the right-of-way but at points where their use does not introduce...