A high SFDR 6-bit 20-MS/s SAR ADC based on time-domain comparator
NASA Astrophysics Data System (ADS)
Xue, Han; Hua, Fan; Qi, Wei; Huazhong, Yang
2013-08-01
This paper presents a 6-bit 20-MS/s high spurious-free dynamic range (SFDR) and low power successive approximation register analog to digital converter (SAR ADC) for the radio-frequency (RF) transceiver front-end, especially for wireless sensor network (WSN) applications. This ADC adopts the modified common-centroid symmetry layout and the successive approximation register reset circuit to improve the linearity and dynamic range. Prototyped in a 0.18-μm 1P6M CMOS technology, the ADC performs a peak SFDR of 55.32 dB and effective number of bits (ENOB) of 5.1 bit for 10 MS/s. At the sample rate of 20 MS/s and the Nyquist input frequency, the 47.39-dB SFDR and 4.6-ENOB are achieved. The differential nonlinearity (DNL) is less than 0.83 LSB and the integral nonlinearity (INL) is less than 0.82 LSB. The experimental results indicate that this SAR ADC consumes a total of 522 μW power and occupies 0.98 mm2.
Fusion method of SAR and optical images for urban object extraction
NASA Astrophysics Data System (ADS)
Jia, Yonghong; Blum, Rick S.; Li, Fangfang
2007-11-01
A new image fusion method of SAR, Panchromatic (Pan) and multispectral (MS) data is proposed. First of all, SAR texture is extracted by ratioing the despeckled SAR image to its low pass approximation, and is used to modulate high pass details extracted from the available Pan image by means of the á trous wavelet decomposition. Then, high pass details modulated with the texture is applied to obtain the fusion product by HPFM (High pass Filter-based Modulation) fusion method. A set of image data including co-registered Landsat TM, ENVISAT SAR and SPOT Pan is used for the experiment. The results demonstrate accurate spectral preservation on vegetated regions, bare soil, and also on textured areas (buildings and road network) where SAR texture information enhances the fusion product, and the proposed approach is effective for image interpret and classification.
17 CFR 274.101 - Form N-SAR, semi-annual report of registered investment companies.
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In-pixel conversion with a 10 bit SAR ADC for next generation X-ray FELs
NASA Astrophysics Data System (ADS)
Lodola, L.; Batignani, G.; Benkechkache, M. A.; Bettarini, S.; Casarosa, G.; Comotti, D.; Dalla Betta, G. F.; Fabris, L.; Forti, F.; Grassi, M.; Latreche, S.; Malcovati, P.; Manghisoni, M.; Mendicino, R.; Morsani, F.; Paladino, A.; Pancheri, L.; Paoloni, E.; Ratti, L.; Re, V.; Rizzo, G.; Traversi, G.; Vacchi, C.; Verzellesi, G.; Xu, H.
2016-07-01
This work presents the design of an interleaved Successive Approximation Register (SAR) ADC, part of the readout channel for the PixFEL detector. The PixFEL project aims at substantially advancing the state-of-the-art in the field of 2D X-ray imaging for applications at the next generation Free Electron Laser (FEL) facilities. For this purpose, the collaboration is developing the fundamental microelectronic building blocks for the readout channel. This work focuses on the design of the ADC carried out in a 65 nm CMOS technology. To obtain a good tradeoff between power consumption, conversion speed and area occupation, an interleaved SAR ADC architecture was adopted.
Koppa, Santosh; Mohandesi, Manouchehr; John, Eugene
2016-12-01
Power consumption is one of the key design constraints in biomedical devices such as pacemakers that are powered by small non rechargeable batteries over their entire life time. In these systems, Analog to Digital Convertors (ADCs) are used as interface between analog world and digital domain and play a key role. In this paper we present the design of an 8-bit Charge Redistribution Successive Approximation Register (CR-SAR) analog to digital converter in standard TSMC 0.18μm CMOS technology for low power and low data rate devices such as pacemakers. The 8-bit optimized CR-SAR ADC achieves low power of less than 250nW with conversion rate of 1KB/s. This ADC achieves integral nonlinearity (INL) and differential nonlinearity (DNL) less than 0.22 least significant bit (LSB) and less than 0.04 LSB respectively as compared to the standard requirement for the INL and DNL errors to be less than 0.5 LSB. The designed ADC operates at 1V supply voltage converting input ranging from 0V to 250mV.
Perkins, David Nikolaus; Gonzales, Antonio I
2014-04-08
A set of co-registered coherent change detection (CCD) products is produced from a set of temporally separated synthetic aperture radar (SAR) images of a target scene. A plurality of transformations are determined, which transformations are respectively for transforming a plurality of the SAR images to a predetermined image coordinate system. The transformations are used to create, from a set of CCD products produced from the set of SAR images, a corresponding set of co-registered CCD products.
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2011-04-01
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Kim, Min-Kyu; Hong, Seong-Kwan; Kwon, Oh-Kyong
2015-12-26
This paper presents a fast multiple sampling method for low-noise CMOS image sensor (CIS) applications with column-parallel successive approximation register analog-to-digital converters (SAR ADCs). The 12-bit SAR ADC using the proposed multiple sampling method decreases the A/D conversion time by repeatedly converting a pixel output to 4-bit after the first 12-bit A/D conversion, reducing noise of the CIS by one over the square root of the number of samplings. The area of the 12-bit SAR ADC is reduced by using a 10-bit capacitor digital-to-analog converter (DAC) with four scaled reference voltages. In addition, a simple up/down counter-based digital processing logic is proposed to perform complex calculations for multiple sampling and digital correlated double sampling. To verify the proposed multiple sampling method, a 256 × 128 pixel array CIS with 12-bit SAR ADCs was fabricated using 0.18 μm CMOS process. The measurement results shows that the proposed multiple sampling method reduces each A/D conversion time from 1.2 μs to 0.45 μs and random noise from 848.3 μV to 270.4 μV, achieving a dynamic range of 68.1 dB and an SNR of 39.2 dB.
High power-efficient asynchronous SAR ADC for IoT devices
NASA Astrophysics Data System (ADS)
Zhang, Beichen; Yao, Bingbing; Liu, Liyuan; Liu, Jian; Wu, Nanjian
2017-10-01
This paper presents a power-efficient 100-MS/s, 10-bit asynchronous successive approximation register (SAR) ADC. It includes an on-chip reference buffer and the total power dissipation is 6.8 mW. To achieve high performance with high power-efficiency in the proposed ADC, bootstrapped switch, redundancy, set-and-down switching approach, dynamic comparator and dynamic logic techniques are employed. The prototype was fabricated using 65 nm standard CMOS technology. At a 1.2-V supply and 100 MS/s, the ADC achieves an SNDR of 56.2 dB and a SFDR of 65.1 dB. The ADC core consumes only 3.1 mW, resulting in a figure of merit (FOM) of 30.27 fJ/conversionstep and occupies an active area of only 0.009 mm2.
Kim, Min-Kyu; Hong, Seong-Kwan; Kwon, Oh-Kyong
2015-01-01
This paper presents a fast multiple sampling method for low-noise CMOS image sensor (CIS) applications with column-parallel successive approximation register analog-to-digital converters (SAR ADCs). The 12-bit SAR ADC using the proposed multiple sampling method decreases the A/D conversion time by repeatedly converting a pixel output to 4-bit after the first 12-bit A/D conversion, reducing noise of the CIS by one over the square root of the number of samplings. The area of the 12-bit SAR ADC is reduced by using a 10-bit capacitor digital-to-analog converter (DAC) with four scaled reference voltages. In addition, a simple up/down counter-based digital processing logic is proposed to perform complex calculations for multiple sampling and digital correlated double sampling. To verify the proposed multiple sampling method, a 256 × 128 pixel array CIS with 12-bit SAR ADCs was fabricated using 0.18 μm CMOS process. The measurement results shows that the proposed multiple sampling method reduces each A/D conversion time from 1.2 μs to 0.45 μs and random noise from 848.3 μV to 270.4 μV, achieving a dynamic range of 68.1 dB and an SNR of 39.2 dB. PMID:26712765
Registration of interferometric SAR images
NASA Technical Reports Server (NTRS)
Lin, Qian; Vesecky, John F.; Zebker, Howard A.
1992-01-01
Interferometric synthetic aperture radar (INSAR) is a new way of performing topography mapping. Among the factors critical to mapping accuracy is the registration of the complex SAR images from repeated orbits. A new algorithm for registering interferometric SAR images is presented. A new figure of merit, the average fluctuation function of the phase difference image, is proposed to evaluate the fringe pattern quality. The process of adjusting the registration parameters according to the fringe pattern quality is optimized through a downhill simplex minimization algorithm. The results of applying the proposed algorithm to register two pairs of Seasat SAR images with a short baseline (75 m) and a long baseline (500 m) are shown. It is found that the average fluctuation function is a very stable measure of fringe pattern quality allowing very accurate registration.
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2010-04-01
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42 CFR 73.0 - Applicability and related requirements.
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2013-10-01
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2014-10-01
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Synthetic aperture radar/LANDSAT MSS image registration
NASA Technical Reports Server (NTRS)
Maurer, H. E. (Editor); Oberholtzer, J. D. (Editor); Anuta, P. E. (Editor)
1979-01-01
Algorithms and procedures necessary to merge aircraft synthetic aperture radar (SAR) and LANDSAT multispectral scanner (MSS) imagery were determined. The design of a SAR/LANDSAT data merging system was developed. Aircraft SAR images were registered to the corresponding LANDSAT MSS scenes and were the subject of experimental investigations. Results indicate that the registration of SAR imagery with LANDSAT MSS imagery is feasible from a technical viewpoint, and useful from an information-content viewpoint.
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Two-step single slope/SAR ADC with error correction for CMOS image sensor.
Tang, Fang; Bermak, Amine; Amira, Abbes; Amor Benammar, Mohieddine; He, Debiao; Zhao, Xiaojin
2014-01-01
Conventional two-step ADC for CMOS image sensor requires full resolution noise performance in the first stage single slope ADC, leading to high power consumption and large chip area. This paper presents an 11-bit two-step single slope/successive approximation register (SAR) ADC scheme for CMOS image sensor applications. The first stage single slope ADC generates a 3-bit data and 1 redundant bit. The redundant bit is combined with the following 8-bit SAR ADC output code using a proposed error correction algorithm. Instead of requiring full resolution noise performance, the first stage single slope circuit of the proposed ADC can tolerate up to 3.125% quantization noise. With the proposed error correction mechanism, the power consumption and chip area of the single slope ADC are significantly reduced. The prototype ADC is fabricated using 0.18 μ m CMOS technology. The chip area of the proposed ADC is 7 μ m × 500 μ m. The measurement results show that the energy efficiency figure-of-merit (FOM) of the proposed ADC core is only 125 pJ/sample under 1.4 V power supply and the chip area efficiency is 84 k μ m(2) · cycles/sample.
SARS-related perceptions in Hong Kong.
Lau, Joseph T F; Yang, Xilin; Pang, Ellie; Tsui, H Y; Wong, Eric; Wing, Yun Kwok
2005-03-01
To understand different aspects of community responses related to severe acute respiratory syndrome (SARS), 2 population-based, random telephone surveys were conducted in June 2003 and January 2004 in Hong Kong. More than 70% of respondents would avoid visiting hospitals or mainland China to avoid contracting SARS. Most respondents believed that SARS could be transmitted through droplets, fomites, sewage, and animals. More than 90% believed that public health measures were efficacious means of prevention; 40.4% believed that SARS would resurge in Hong Kong; and approximately equals 70% would then wear masks in public places. High percentages of respondents felt helpless, horrified, and apprehensive because of SARS. Approximately 16% showed signs of posttraumatic symptoms, and approximately equals 40% perceived increased stress in family or work settings. The general public in Hong Kong has been very vigilant about SARS but needs to be more psychologically prepared to face a resurgence of the epidemic.
NASA Astrophysics Data System (ADS)
Liu, Wei; Wei, Tingcun; Li, Bo; Yang, Lifeng; Xue, Feifei; Hu, Yongcai
2016-05-01
This paper presents a 12-bit 1 MS/s successive approximation register-analog to digital converter (SAR-ADC) for the 32-channel front-end electronics of CZT-based PET imaging system. To reduce the capacitance mismatch, instead of the fractional capacitor, the unit capacitor is used as the bridge capacitor in the split-capacitor digital to analog converter (DAC) circuit. In addition, in order to eliminate the periodical DNL errors of -1 LSB which often exists in the SAR-ADC using the charge-redistributed DAC, a calibration algorithm is proposed and verified by the experiments. The proposed 12-bit 1 MS/s SAR-ADC is designed and implemented using a 0.35 μm CMOS technology, it occupies only an active area of 986×956 μm2. The measurement results show that, at the power supply of 3.3/5.0 V and the sampling rate of 1 MS/s, the ADC with calibration has a signal-to-noise-and-distortion ratio (SINAD) of 67.98 dB, the power dissipation of 5 mW, and a figure of merit (FOM) of 2.44 pJ/conv.-step. This ADC is with the features of high accuracy, low power and small layout area, it is especially suitable to the one-chip integration of the front-end readout electronics.
NASA Astrophysics Data System (ADS)
Xue, F.; Gao, W.; Duan, Y.; Zheng, R.; Hu, Y.
2018-02-01
This paper presents a 12-bit pipelined successive approximation register (SAR) ADC for CZT-based hard X-ray Imager. The proposed ADC is comprised of a first-stage 6-bit SAR-based Multiplying Digital Analog Converter (MDAC) and a second-stage 8-bit SAR ADC. A novel MDAC architecture using Vcm-based Switching method is employed to maximize the energy efficiency and improve the linearity of the ADC. Moreover, the unit-capacitor array instead of the binary-weighted capacitor array is adopted to improve the conversion speed and linearity of the ADC in the first-stage MDAC. In addition, a new layout design method for the binary-weighted capacitor array is proposed to reduce the capacitor mismatches and make the routing become easier and less-time-consuming. Finally, several radiation-hardened-by-design technologies are adopted in the layout design against space radiation effects. The prototype chip was fabricated in 0.18 μm mixed-signal 1.8V/3.3V process and operated at 1.8 V supply. The chip occupies a core area of only 0.58 mm2. The proposed pipelined SAR ADC achieves a peak signal-to-noise-and-distortion ratio (SNDR) of 66.7 dB and a peak spurious-free dynamic range (SFDR) of 78.6 dB at 10 MS/s sampling rate and consumes 10 mW. The figure of merit (FOM) of the proposed ADC is 0.56 pJ/conversion-step.
SAR/LANDSAT image registration study
NASA Technical Reports Server (NTRS)
Murphrey, S. W. (Principal Investigator)
1978-01-01
The author has identified the following significant results. Temporal registration of synthetic aperture radar data with LANDSAT-MSS data is both feasible (from a technical standpoint) and useful (from an information-content viewpoint). The greatest difficulty in registering aircraft SAR data to corrected LANDSAT-MSS data is control-point location. The differences in SAR and MSS data impact the selection of features that will serve as a good control points. The SAR and MSS data are unsuitable for automatic computer correlation of digital control-point data. The gray-level data can not be compared by the computer because of the different response characteristics of the MSS and SAR images.
Linear Approximation SAR Azimuth Processing Study
NASA Technical Reports Server (NTRS)
Lindquist, R. B.; Masnaghetti, R. K.; Belland, E.; Hance, H. V.; Weis, W. G.
1979-01-01
A segmented linear approximation of the quadratic phase function that is used to focus the synthetic antenna of a SAR was studied. Ideal focusing, using a quadratic varying phase focusing function during the time radar target histories are gathered, requires a large number of complex multiplications. These can be largely eliminated by using linear approximation techniques. The result is a reduced processor size and chip count relative to ideally focussed processing and a correspondingly increased feasibility for spaceworthy implementation. A preliminary design and sizing for a spaceworthy linear approximation SAR azimuth processor meeting requirements similar to those of the SEASAT-A SAR was developed. The study resulted in a design with approximately 1500 IC's, 1.2 cubic feet of volume, and 350 watts of power for a single look, 4000 range cell azimuth processor with 25 meters resolution.
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SEMICONDUCTOR INTEGRATED CIRCUITS A 10-bit 200-kS/s SAR ADC IP core for a touch screen SoC
NASA Astrophysics Data System (ADS)
Xingyuan, Tong; Yintang, Yang; Zhangming, Zhu; Wenfang, Sheng
2010-10-01
Based on a 5 MSBs (most-significant-bits)-plus-5 LSBs (least-significant-bits) C-R hybrid D/A conversion and low-offset pseudo-differential comparison approach, with capacitor array axially symmetric layout topology and resistor string low gradient mismatch placement method, an 8-channel 10-bit 200-kS/s SAR ADC (successive-approximation-register analog-to-digital converter) IP core for a touch screen SoC (system-on-chip) is implemented in a 0.18 μm 1P5M CMOS logic process. Design considerations for the touch screen SAR ADC are included. With a 1.8 V power supply, the DNL (differential non-linearity) and INL (integral non-linearity) of this converter are measured to be about 0.32 LSB and 0.81 LSB respectively. With an input frequency of 91 kHz at 200-kS/s sampling rate, the spurious-free dynamic range and effective-number-of-bits are measured to be 63.2 dB and 9.15 bits respectively, and the power is about 136 μW. This converter occupies an area of about 0.08 mm2. The design results show that it is very suitable for touch screen SoC applications.
Software For Tie-Point Registration Of SAR Data
NASA Technical Reports Server (NTRS)
Rignot, Eric; Dubois, Pascale; Okonek, Sharon; Van Zyl, Jacob; Burnette, Fred; Borgeaud, Maurice
1995-01-01
SAR-REG software package registers synthetic-aperture-radar (SAR) image data to common reference frame based on manual tie-pointing. Image data can be in binary, integer, floating-point, or AIRSAR compressed format. For example, with map of soil characteristics, vegetation map, digital elevation map, or SPOT multispectral image, as long as user can generate binary image to be used by tie-pointing routine and data are available in one of the previously mentioned formats. Written in FORTRAN 77.
Wivell, Charles E.; Olmsted, Coert; Steinwand, Daniel R.; Taylor, Christopher
1993-01-01
Because the pixel location in a line of Synthetic Aperture Radar (SAR) image data is directly related to the distance the pixel is from the radar, terrain elevations cause large displacement errors in the geo-referenced location of the pixel. This is especially true for radar systems with small angles between the nadir and look vectors. Thus, to geo-register a SAR image accurately, the terrain of the area must be taken into account. (Curlander et al., 1987; Kwok et al., 1987, Schreier et al., 1990; Wivell et al., 1992). As part of the 1992 National Aeronautics and Space Administration's Earth Observing System Version 0 activities, a prototype SAR geocod-. ing and terrain correction system was developed at the US. Geological Survey's (USGS) E~os Data Center (EDC) in Sioux Falls, South Dakota. Using this system with 3-arc-second digital elevation models (DEMs) mosaicked at the ED^ Alaska Field Office, 21 ERS-I s.4~ scenes acquired at the Alaska SAR Facility were automatically geocoded, terrain corrected, and mosaicked. The geo-registered scenes were mosaicked using a simple concatenation.
de Wilde, Adriaan H; Falzarano, Darryl; Zevenhoven-Dobbe, Jessika C; Beugeling, Corrine; Fett, Craig; Martellaro, Cynthia; Posthuma, Clara C; Feldmann, Heinz; Perlman, Stanley; Snijder, Eric J
2017-01-15
Currently, there is no registered treatment for infections with emerging zoonotic coronaviruses like SARS- and MERS-coronavirus. We here report that in cultured cells low-micromolar concentrations of alisporivir, a non-immunosuppressive cyclosporin A-analog, inhibit the replication of four different coronaviruses, including MERS- and SARS-coronavirus. Ribavirin was found to further potentiate the antiviral effect of alisporivir in these cell culture-based infection models, but this combination treatment was unable to improve the outcome of SARS-CoV infection in a mouse model. Nevertheless, our data provide a basis to further explore the potential of Cyp inhibitors as host-directed, broad-spectrum inhibitors of coronavirus replication. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.
Deformation of Copahue volcano: Inversion of InSAR data using a genetic algorithm
NASA Astrophysics Data System (ADS)
Velez, Maria Laura; Euillades, Pablo; Caselli, Alberto; Blanco, Mauro; Díaz, Jose Martínez
2011-04-01
The Copahue volcano is one of the most active volcanoes in Argentina with eruptions having been reported as recently as 1992, 1995 and 2000. A deformation analysis using the Differential Synthetic Aperture Radar technique (DInSAR) was performed on Copahue-Caviahue Volcanic Complex (CCVC) from Envisat radar images between 2002 and 2007. A deformation rate of approximately 2 cm/yr was calculated, located mostly on the north-eastern flank of Copahue volcano, and assumed to be constant during the period of the interferograms. The geometry of the source responsible for the deformation was evaluated from an inversion of the mean velocity deformation measurements using two different models based on pressure sources embedded in an elastic homogeneous half-space. A genetic algorithm was applied as an optimization tool to find the best fit source. Results from inverse modelling indicate that a source located beneath the volcano edifice at a mean depth of 4 km is producing a volume change of approximately 0.0015 km/yr. This source was analysed considering the available studies of the area, and a conceptual model of the volcanic-hydrothermal system was designed. The source of deformation is related to a depressurisation of the system that results from the release of magmatic fluids across the boundary between the brittle and plastic domains. These leakages are considered to be responsible for the weak phreatic eruptions recently registered at the Copahue volcano.
Confirmation of quasi-static approximation in SAR evaluation for a wireless power transfer system.
Hirata, Akimasa; Ito, Fumihiro; Laakso, Ilkka
2013-09-07
The present study discusses the applicability of the magneto-quasi-static approximation to the calculation of the specific absorption rate (SAR) in a cylindrical model for a wireless power transfer system. Resonant coils with different parameters were considered in the 10 MHz band. A two-step quasi-static method that is comprised of the method of moments and the scalar-potential finite-difference methods is applied, which can consider the effects of electric and magnetic fields on the induced SAR separately. From our computational results, the SARs obtained from our quasi-static method are found to be in good agreement with full-wave analysis for different positions of the cylindrical model relative to the wireless power transfer system, confirming the applicability of the quasi-static approximation in the 10 MHz band. The SAR induced by the external electric field is found to be marginal as compared to that induced by the magnetic field. Thus, the dosimetry for the external magnetic field, which may be marginally perturbed by the presence of biological tissue, is confirmed to be essential for SAR compliance in the 10 MHz band or lower. This confirmation also suggests that the current in the coil rather than the transferred power is essential for SAR compliance.
Vibrational Spectra of Cryogenic Peptide Ions Using H_2 Predissociation Spectroscopy
NASA Astrophysics Data System (ADS)
Leavitt, Christopher M.; Wolk, Arron B.; Kamrath, Michael Z.; Garand, Etienne; Johnson, Mark A.; van Stipdonk, Michael J.
2011-06-01
H_2 predissociation spectroscopy was used to collect the vibrational spectra of the model protonated peptides, GlyGly, GlySar, SarGly and SarSar (Gly=glycine and Sar=sarcosine). H_2 molecules were condensed onto protonated peptide ions in a quadrupole ion trap cooled to approximately 10 K. The resulting spectra yielded clearly resolved vibrational transitions throughout the mid IR region, 600-4200 Cm-1, with linewidths of approximately 6 Cm-1. Protonation nominally occurred on the amino terminus giving rise to an intramolecular H-bond between the protonated amine and the neighboring amide oxygen. The sarcosine containing peptides incorporate a methyl group onto either the amino group or the amide nitrogen causing the peptide backbone to adopt a different structure, resulting in the shifts in the amide I and II bands and the N-H stretches.
Picosecond Resolution Time-to-Digital Converter Using Gm-C Integrator and SAR-ADC
NASA Astrophysics Data System (ADS)
Xu, Zule; Miyahara, Masaya; Matsuzawa, Akira
2014-04-01
A picosecond resolution time-to-digital converter (TDC) is presented. The resolution of a conventional delay chain TDC is limited by the delay of a logic buffer. Various types of recent TDCs are successful in breaking this limitation, but they require a significant calibration effort to achieve picosecond resolution with a sufficient linear range. To address these issues, we propose a simple method to break the resolution limitation without any calibration: a Gm-C integrator followed by a successive approximation register analog-to-digital converter (SAR-ADC). This translates the time interval into charge, and then the charge is quantized. A prototype chip was fabricated in 90 nm CMOS. The measurement results reveal a 1 ps resolution, a -0.6/0.7 LSB differential nonlinearity (DNL), a -1.1/2.3 LSB integral nonlinearity (INL), and a 9-bit range. The measured 11.74 ps single-shot precision is caused by the noise of the integrator. We analyze the noise of the integrator and propose an improved front-end circuit to reduce this noise. The proposal is verified by simulations showing the maximum single-shot precision is less than 1 ps. The proposed front-end circuit can also diminish the mismatch effects.
Findlay, R P; Dimbylow, P J
2006-05-07
Finite-difference time-domain (FDTD) calculations have been performed to investigate the frequency dependence of the specific energy absorption rate (SAR) in a seated voxel model of the human body. The seated model was derived from NORMAN (NORmalized MAN), an anatomically realistic voxel phantom in the standing posture with arms to the side. Exposure conditions included both vertically and horizontally polarized plane wave electric fields between 10 MHz and 3 GHz. The resolution of the voxel model was 4 mm for frequencies up to 360 MHz and 2 mm for calculations in the higher frequency range. The reduction in voxel size permitted the calculation of SAR at these higher frequencies using the FDTD method. SAR values have been calculated for the seated adult phantom and scaled versions representing 10-, 5- and 1-year-old children under isolated and grounded conditions. These scaled models do not exactly reproduce the dimensions and anatomy of children, but represent good geometric information for a seated child. Results show that, when the field is vertically polarized, the sitting position causes a second, smaller resonance condition not seen in resonance curves for the phantom in the standing posture. This occurs at approximately 130 MHz for the adult model when grounded. Partial-body SAR calculations indicate that the upper and lower regions of the body have their own resonant frequency at approximately 120 MHz and approximately 160 MHz, respectively, when the grounded adult model is orientated in the sitting position. These combine to produce this second resonance peak in the whole-body averaged SAR values calculated. Two resonance peaks also occur for the sitting posture when the incident electric field is horizontally polarized. For the adult model, the peaks in the whole-body averaged SAR occur at approximately 180 and approximately 600 MHz. These peaks are due to resonance in the arms and feet, respectively. Layer absorption plots and colour images of SAR in individual voxels show the specific regions in which the seated human body absorbs the incident field. External electric field values required to produce the ICNIRP basic restrictions were derived from SAR calculations and compared with ICNIRP reference levels. This comparison shows that the reference levels provide a conservative estimate of the ICNIRP whole-body averaged SAR restriction, with the exception of the region above 1.4 GHz for the scaled 1-year-old model.
NASA Technical Reports Server (NTRS)
Curlander, John C.; Kwok, Ronald; Pang, Shirley S.; Pang, Amy A.
1990-01-01
Spaceborne synthetic-aperture-radar (SAR) images useful for mapping of planets and investigations in Earth sciences. Produces multiframe mosaic by combining images along ground track, in adjacent cross-track swaths, or in ascending and descending passes. Images registered with geocoded maps such as ones produced by MAPJTC (NPO-17718), required as input. Minimal intervention by operator required. MOSK implemented on DEC VAX 11/785 computer running VMS 4.5. Most subroutines in FORTRAN, but three in MAXL and one in APAL.
NASA Technical Reports Server (NTRS)
Hall, D. K.; Ormsby, J. P.
1983-01-01
Three Seasat synthetic aperture radar (SAR) and three Landsat multispectral scanner subsystem (MSS) scenes of three areas of Alaska were analyzed for hydrological information. The areas were: the Dease Inlet in northern Alaska and its oriented or thaw lakes, the Ruth and Tokositna valley glaciers in south central Alaska, and the Malaspina piedmont glacier on Alaska's southern coast. Results for the first area showed that the location and identification of some older remnant lake basins were more easily determined in the registered data using an MSS/SAR overlay than in either SAR or MSS data alone. Separately, both SAR and MSS data were useful for determination of surging glaciers based on their distinctive medial moraines, and Landsat data were useful for locating the glacier firn zone. For the Malaspina Glacier scenes, the SAR data were useful for locating heavily crevassed ice beneath glacial debris, and Landsat provided data concerning the extent of the debris overlying the glacier.
78 FR 44983 - Submission for OMB Review; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-25
..., approximately 14.25 hours in preparing and filing reports on Form N-SAR and that the total hour burden for all..., Washington, DC 20549-0213. Extension: Form N-SAR. OMB Control No. 3235-0330, SEC File No. 270-292. Notice is... Office of Management and Budget (``OMB'') for extension and approval. Form N-SAR (OMB Control No. 3235...
75 FR 57305 - Submission for OMB Review; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-20
..., approximately 14.31 hours in preparing and filing reports on Form N-SAR and that the total hour burden for all..., Washington, DC 20549-0213. Extension: Form N-SAR, SEC File No. 270-292, OMB Control No. 3235-0330. Notice is... Office of Management and Budget (``OMB'') for extension and approval. Form N-SAR (OMB Control No. 3235...
FDTD simulations to assess the performance of CFMA-434 applicators for superficial hyperthermia.
Kok, H Petra; De Greef, Martijn; Correia, Davi; Vörding, Paul J Zum Vörde Sive; Van Stam, Gerard; Gelvich, Edward A; Bel, Arjan; Crezee, Johannes
2009-01-01
Contact flexible microstrip applicators (CFMA), operating at 434 MHz, are applied at the Academic Medical Center (AMC) for superficial hyperthermia (e.g. chest wall recurrences and melanoma). This paper investigates the performance of CFMA, evaluating the stability of the specific absorption rate (SAR) distribution, effective heating depth (EHD) and effective field size (EFS) under different conditions. Simulations were performed using finite differences and were compared to existing measurement data, performed using a rectangular phantom with a superficial fat-equivalent layer of 1 cm and filled with saline solution. The electrode plates of the applicators measure approximately 7 x 20, 29 x 21 and 20 x 29 cm(2). Bolus thickness varied between 1 and 2 cm. The impact of the presence of possible air layers between the rubber frame and the electrodes on the SAR distribution was investigated. The EHD was approximately 1.4 cm and the EFS ranged between approximately 60 and approximately 300 cm(2), depending on the applicator type. Both measurements and simulations showed a split-up of the SAR focus with a 2 cm water bolus. The extent and location of air layers has a strong influence on the shape and size of the iso-SAR contours with a value higher than 50%, but the impact on EFS and EHD is limited. Simulations, confirmed by measurements, showed that the presence of air between the rubber and the electrodes changes the iso-SAR contours, but the impact on the EFS and EHD is limited.
Jo, Min-Jeong; Jung, Hyung-Sup; Yun, Sang-Ho
2017-07-14
We reconstructed the three-dimensional (3D) surface displacement field of the 24 August 2014 M6.0 South Napa earthquake using SAR data from the Italian Space Agency's COSMO-SkyMed and the European Space Agency's Sentinel-1A satellites. Along-track and cross-track displacements produced with conventional SAR interferometry (InSAR) and multiple-aperture SAR interferometry (MAI) techniques were integrated to retrieve the east, north, and up components of surface deformation. The resulting 3D displacement maps clearly delineated the right-lateral shear motion of the fault rupture with a maximum surface displacement of approximately 45 cm along the fault's strike, showing the east and north components of the trace particularly clearly. These maps also suggested a better-constrained model for the South Napa earthquake. We determined a strike of approximately 338° and dip of 85° by applying the Okada dislocation model considering a single patch with a homogeneous slip motion. Using the distributed slip model obtained by a linear solution, we estimated that a peak slip of approximately 1.7 m occurred around 4 km depth from the surface. 3D modelling using the retrieved 3D maps helps clarify the fault's nature and thus characterize its behaviour.
2008-10-01
resolution orthophoto and LiDAR datasets, as well as for the vegetation modeling conducted for SAR FAR mitigation. 3.4.4 Navigation Systems An Applanix A...these accuracies. By registering eight cardinal pass-direction images per tile to the orthophotography and to each other, the horizontal error in... orthophoto image, which successfully increased the HSI image resolution to 0.25-m. 22 Table 4. SAR Performance Data. Type of Performance
Superpixel edges for boundary detection
Moya, Mary M.; Koch, Mark W.
2016-07-12
Various embodiments presented herein relate to identifying one or more edges in a synthetic aperture radar (SAR) image comprising a plurality of superpixels. Superpixels sharing an edge (or boundary) can be identified and one or more properties of the shared superpixels can be compared to determine whether the superpixels form the same or two different features. Where the superpixels form the same feature the edge is identified as an internal edge. Where the superpixels form two different features, the edge is identified as an external edge. Based upon classification of the superpixels, the external edge can be further determined to form part of a roof, wall, etc. The superpixels can be formed from a speckle-reduced SAR image product formed from a registered stack of SAR images, which is further segmented into a plurality of superpixels. The edge identification process is applied to the SAR image comprising the superpixels and edges.
Rapid Disaster Analysis based on Remote Sensing: A Case Study about the Tohoku Tsunami Disaster 2011
NASA Astrophysics Data System (ADS)
Yang, C. H.; Soergel, U.; Lanaras, Ch.; Baltsavias, E.; Cho, K.; Remondino, F.; Wakabayashi, H.
2014-09-01
In this study, we present first results of RAPIDMAP, a project funded by European Union in a framework aiming to foster the cooperation of European countries with Japan in R&D. The main objective of RAPIDMAP is to construct a Decision Support System (DSS) based on remote sensing data and WebGIS technologies, where users can easily access real-time information assisting with disaster analysis. In this paper, we present a case study of the Tohoku Tsunami Disaster 2011. We address two approaches namely change detection based on SAR data and co-registration of optical and SAR satellite images. With respect to SAR data, our efforts are subdivided into three parts: (1) initial coarse change detection for entire area, (2) flood area detection, and (3) linearfeature change detection. The investigations are based on pre- and post-event TerraSAR-X images. In (1), two pre- and post-event TerraSAR-X images are accurately co-registered and radiometrically calibrated. Data are fused in a false-color image that provides a quick and rough overview of potential changes, which is useful for initial decision making and identifying areas worthwhile to be analysed further in more depth. However, a bunch of inevitable false alarms appear within the scene caused by speckle, temporal decorrelation, co-registration inaccuracy and so on. In (2), the post-event TerraSAR-X data are used to extract the flood area by using thresholding and morphological approaches. The validated result indicates that using SAR data combining with suitable morphological approaches is a quick and effective way to detect flood area. Except for usage of SAR data, the false-color image composed of optical images are also used to detect flood area for further exploration in this part. In (3), Curvelet filtering is applied in the difference image of pre- and post-event TerraSAR-X images not only to suppress false alarms of irregular-features, but also to enhance the change signals of linear-features (e.g. buildings) in settlements. Afterwards, thresholding is exploited to extract the linear-feature changes. In rapid mapping of disasters various sensors are often employed, including optical and SAR, since they provide complementary information. Such data needs to be analyzed in an integrated fashion and the results from each dataset should be integrated in a GIS with a common coordinate reference system. Thus, if no orthoimages can be generated, the images should be co-registered employing matching of common features. We present results of co-registration between optical (FORMOSAT-2) and TerraSAR-X images based on different matching methods, and also techniques for detecting and eliminating matching errors.
A low-power small-area ADC array for IRFPA readout
NASA Astrophysics Data System (ADS)
Zhong, Shengyou; Yao, Libin
2013-09-01
The readout integrated circuit (ROIC) is a bridge between the infrared focal plane array (IRFPA) and image processing circuit in an infrared imaging system. The ROIC is the first part of signal processing circuit and connected to detectors directly, so its performance will greatly affect the detector or even the whole imaging system performance. With the development of CMOS technologies, it's possible to digitalize the signal inside the ROIC and develop the digital ROIC. Digital ROIC can reduce complexity of the whole system and improve the system reliability. More importantly, it can accommodate variety of digital signal processing techniques which the traditional analog ROIC cannot achieve. The analog to digital converter (ADC) is the most important building block in the digital ROIC. The requirements for ADCs inside the ROIC are low power, high dynamic range and small area. In this paper we propose an RC hybrid Successive Approximation Register (SAR) ADC as the column ADC for digital ROIC. In our proposed ADC structure, a resistor ladder is used to generate several voltages. The proposed RC hybrid structure not only reduces the area of capacitor array but also releases requirement for capacitor array matching. Theory analysis and simulation show RC hybrid SAR ADC is suitable for ADC array applications
Implementation of integrated circuit and design of SAR ADC for fully implantable hearing aids.
Kim, Jong Hoon; Lee, Jyung Hyun; Cho, Jin-Ho
2017-07-20
The hearing impaired population has been increasing; many people suffer from hearing problems. To deal with this difficulty, various types of hearing aids are being rapidly developed. In particular, fully implantable hearing aids are being actively studied to improve the performance of existing hearing aids and to reduce the stigma of hearing loss patients. It has to be of small size and low-power consumption for easy implantation and long-term use. The objective of the study was to implement a small size and low-power consumption successive approximation register analog-to-digital converter (SAR ADC) for fully implantable hearing aids. The ADC was selected as the SAR ADC because its analog circuit components are less required by the feedback circuit of the SAR ADC than the sigma-delta ADC which is conventionally used in hearing aids, and it has advantages in the area and power consumption. So, the circuit of SAR ADC is designed considering the speech region of humans because the objective is to deliver the speech signals of humans to hearing loss patients. If the switch of sample and hold works in the on/off positions, the charge injection and clock feedthrough are produced by a parasitic capacitor. These problems affect the linearity of the hold voltage, and as a result, an error of the bit conversion is generated. In order to solve the problem, a CMOS switch that consists of NMOS and PMOS was used, and it reduces the charge injection because the charge carriers in the NMOS and PMOS have inversed polarity. So, 16 bit conversion is performed before the occurrence of the Least Significant Bit (LSB) error. In order to minimize the offset voltage and power consumption of the designed comparator, we designed a preamplifier with current mirror. Therefore, the power consumption was reduced by the power control switch used in the comparator. The layout of the designed SAR ADC was performed by Virtuoso Layout Editor (Cadence, USA). In the layout result, the size of the designed SAR ADC occupied 124.9 μm × 152.1 μm. The circuit verification was performed by layout versus schematic (LVS) and design rule check (DRC) which are provided by Calibre (Mentor Graphics, USA), and it was confirmed that there was no error. The designed SAR ADC was implemented in SMIC 180 nm CMOS technology. The operation of the manufactured SAR ADC was confirmed by using an oscilloscope. The SAR ADC output was measured using a distortion meter (HM 8027), when applying pure tone sounds of 94 dB SPL at 500, 800, and 1600 Hz regions. As a result, the THD performance of the proposed chip was satisfied with the ANSI. s3. 22. 2003 standard. We proposed a low-power 16-bit 32 kHz SAR ADC for fully implantable hearing aids. The manufactured SAR ADC based on this design was confirmed to have advantages in power consumption and size through the comparison with the conventional ADC. Therefore, the manufactured SAR ADC is expected to be used in the implantable medical device field and speech signal processing field, which require small size and low power consumption.
Agile waveforms for joint SAR-GMTI processing
NASA Astrophysics Data System (ADS)
Jaroszewski, Steven; Corbeil, Allan; McMurray, Stephen; Majumder, Uttam; Bell, Mark R.; Corbeil, Jeffrey; Minardi, Michael
2016-05-01
Wideband radar waveforms that employ spread-spectrum techniques were investigated and experimentally tested. The waveforms combine bi-phase coding with a traditional LFM chirp and are applicable to joint SAR-GMTI processing. After de-spreading, the received signals can be processed to support simultaneous GMTI and high resolution SAR imaging missions by airborne radars. The spread spectrum coding techniques can provide nearly orthogonal waveforms and offer enhanced operations in some environments by distributing the transmitted energy over a large instantaneous bandwidth. The LFM component offers the desired Doppler tolerance. In this paper, the waveforms are formulated and a shift-register approach for de-spreading the received signals is described. Hardware loop-back testing has shown the feasibility of using these waveforms in experimental radar test bed.
SARS-related Perceptions in Hong Kong
Yang, Xilin; Pang, Ellie; Tsui, H.Y.; Wong, Eric; Wing, Yun Kwok
2005-01-01
To understand different aspects of community responses related to severe acute respiratory syndrome (SARS), 2 population-based, random telephone surveys were conducted in June 2003 and January 2004 in Hong Kong. More than 70% of respondents would avoid visiting hospitals or mainland China to avoid contracting SARS. Most respondents believed that SARS could be transmitted through droplets, fomites, sewage, and animals. More than 90% believed that public health measures were efficacious means of prevention; 40.4% believed that SARS would resurge in Hong Kong; and ≈70% would then wear masks in public places. High percentages of respondents felt helpless, horrified, and apprehensive because of SARS. Approximately 16% showed signs of posttraumatic symptoms, and ≈40% perceived increased stress in family or work settings. The general public in Hong Kong has been very vigilant about SARS but needs to be more psychologically prepared to face a resurgence of the epidemic. PMID:15757557
SARS: caring for patients in Hong Kong.
Chung, Betty Pui Man; Wong, Thomas Kwok Shing; Suen, Esther Suk Bing; Chung, Joanne Wai Yee
2005-04-01
To explore in depth the experiences of nurses' caring for SARS patients in Hong Kong. Severe Acute Respiratory Syndrome (SARS) dramatically demonstrates the global havoc that can be wreaked by a newly emerging infectious disease. The current literature either has a predominantly biomedical focus or deals with the psychological impact on healthcare workers. Published studies on the lived experience of nurses caring for SARS patients are currently lacking. A phenomenological design. Using methods consistent with Husserl's philosophy, eight Registered Nurses working in three regional hospitals in Hong Kong were invited to participate in sharing their lived experience of caring for SARS patients and data were analysed using Colaizzi's approach. The three major themes explicated were: the various emotions experienced in caring for SARS patients, the concept of uncertainty and revisiting the 'taken for granted' features of nursing. These themes, when taken together, describe the essence of the voyage undertaken by nurses who cared for SARS patients during the outbreak. The findings of this study indicate that extensive and ongoing support is needed to prepare and enable nurses to care for SARS patients during a crisis and make it easier for nurses to deal with the various uncertainties. The essence of caring for SARS patients is highlighted in this study. The experience of caring for SARS patients prompts nurses to find meaning in their experience(s), and to develop knowledge and attitudes on how best to care for patients and prepare for a new crisis in the future. This paper considers a more in-depth understanding of the lived experience of nurses during the crisis and the relevance of this perspective for education and support of nurses.
LUCAS(™)2 in Danish Search and Rescue Helicopters.
Winther, Kasper; Bleeg, René Christian
2016-01-01
Prehospital resuscitation is often challenging. Giving uninterrupted and effective compressions is relatively impossible during transportation. In 2012, The Royal Danish Air Force received a donation of 8 mechanical chest compression devices (LUCAS(™)2; Physio-Control/Jolife AB, Lund, Sweden) to be used onboard the Danish search and rescue (SAR) helicopters. The scope of this investigation was to establish whether or not mechanical chest compression devices should be considered a necessity onboard the Danish SAR helicopters. Data were compiled from SAR medical journals. From the data collected, observations were made as to when LUCAS(™)2 was used and what diagnosis the SAR physician made. One thousand ninety missions were registered in the 24-month research period, and LUCAS(™)2 was used in 25 missions. Cardiac emergencies amounted for 25% of the missions. The Danish SAR helicopters retrieved 33 drowned/hypothermic patients during the research period, and the LUCAS(™)2 was used in 11 of the patients requiring resuscitation. The LUCAS(™)2 was frequently used during other emergencies like sudden cardiac arrest. Cardiac emergencies were the predominant type of mission. LUCAS(™)2 is now considered mandatory on Danish SAR helicopters. Copyright © 2016 Air Medical Journal Associates. Published by Elsevier Inc. All rights reserved.
A Reconfigurable Readout Integrated Circuit for Heterogeneous Display-Based Multi-Sensor Systems
Park, Kyeonghwan; Kim, Seung Mok; Eom, Won-Jin; Kim, Jae Joon
2017-01-01
This paper presents a reconfigurable multi-sensor interface and its readout integrated circuit (ROIC) for display-based multi-sensor systems, which builds up multi-sensor functions by utilizing touch screen panels. In addition to inherent touch detection, physiological and environmental sensor interfaces are incorporated. The reconfigurable feature is effectively implemented by proposing two basis readout topologies of amplifier-based and oscillator-based circuits. For noise-immune design against various noises from inherent human-touch operations, an alternate-sampling error-correction scheme is proposed and integrated inside the ROIC, achieving a 12-bit resolution of successive approximation register (SAR) of analog-to-digital conversion without additional calibrations. A ROIC prototype that includes the whole proposed functions and data converters was fabricated in a 0.18 μm complementary metal oxide semiconductor (CMOS) process, and its feasibility was experimentally verified to support multiple heterogeneous sensing functions of touch, electrocardiogram, body impedance, and environmental sensors. PMID:28368355
A Reconfigurable Readout Integrated Circuit for Heterogeneous Display-Based Multi-Sensor Systems.
Park, Kyeonghwan; Kim, Seung Mok; Eom, Won-Jin; Kim, Jae Joon
2017-04-03
This paper presents a reconfigurable multi-sensor interface and its readout integrated circuit (ROIC) for display-based multi-sensor systems, which builds up multi-sensor functions by utilizing touch screen panels. In addition to inherent touch detection, physiological and environmental sensor interfaces are incorporated. The reconfigurable feature is effectively implemented by proposing two basis readout topologies of amplifier-based and oscillator-based circuits. For noise-immune design against various noises from inherent human-touch operations, an alternate-sampling error-correction scheme is proposed and integrated inside the ROIC, achieving a 12-bit resolution of successive approximation register (SAR) of analog-to-digital conversion without additional calibrations. A ROIC prototype that includes the whole proposed functions and data converters was fabricated in a 0.18 μm complementary metal oxide semiconductor (CMOS) process, and its feasibility was experimentally verified to support multiple heterogeneous sensing functions of touch, electrocardiogram, body impedance, and environmental sensors.
Choi, Subin; Park, Kyeonghwan; Lee, Seungwook; Lim, Yeongjin; Oh, Byungjoo; Chae, Hee Young; Park, Chan Sam; Shin, Heugjoo; Kim, Jae Joon
2018-03-02
This paper presents a resolution-reconfigurable wide-range resistive sensor readout interface for wireless multi-gas monitoring applications that displays results on a smartphone. Three types of sensing resolutions were selected to minimize processing power consumption, and a dual-mode front-end structure was proposed to support the detection of a variety of hazardous gases with wide range of characteristic resistance. The readout integrated circuit (ROIC) was fabricated in a 0.18 μm CMOS process to provide three reconfigurable data conversions that correspond to a low-power resistance-to-digital converter (RDC), a 12-bit successive approximation register (SAR) analog-to-digital converter (ADC), and a 16-bit delta-sigma modulator. For functional feasibility, a wireless sensor system prototype that included in-house microelectromechanical (MEMS) sensing devices and commercial device products was manufactured and experimentally verified to detect a variety of hazardous gases.
Lim, Byoung-Gyun; Woo, Jea-Choon; Lee, Hee-Young; Kim, Young-Soo
2008-01-01
Synthetic wideband waveforms (SWW) combine a stepped frequency CW waveform and a chirp signal waveform to achieve high range resolution without requiring a large bandwidth or the consequent very high sampling rate. If an efficient algorithm like the range-Doppler algorithm (RDA) is used to acquire the SAR images for synthetic wideband signals, errors occur due to approximations, so the images may not show the best possible result. This paper proposes a modified subpulse SAR processing algorithm for synthetic wideband signals which is based on RDA. An experiment with an automobile-based SAR system showed that the proposed algorithm is quite accurate with a considerable improvement in resolution and quality of the obtained SAR image. PMID:27873984
Building detection in SAR imagery
DOE Office of Scientific and Technical Information (OSTI.GOV)
Steinbach, Ryan Matthew
Current techniques for building detection in Synthetic Aperture Radar (SAR) imagery can be computationally expensive and/or enforce stringent requirements for data acquisition. I present two techniques that are effective and efficient at determining an approximate building location. This approximate location can be used to extract a portion of the SAR image to then perform a more robust detection. The proposed techniques assume that for the desired image, bright lines and shadows, SAR artifact effects, are approximately labeled. These labels are enhanced and utilized to locate buildings, only if the related bright lines and shadows can be grouped. In order tomore » find which of the bright lines and shadows are related, all of the bright lines are connected to all of the shadows. This allows the problem to be solved from a connected graph viewpoint, where the nodes are the bright lines and shadows and the arcs are the connections between bright lines and shadows. For the first technique, constraints based on angle of depression and the relationship between connected bright lines and shadows are applied to remove unrelated arcs. The second technique calculates weights for the connections and then performs a series of increasingly relaxed hard and soft thresholds. This results in groups of various levels on their validity. Once the related bright lines and shadows are grouped, their locations are combined to provide an approximate building location. Experimental results demonstrate the outcome of the two techniques. The two techniques are compared and discussed.« less
Burcher, E; Warner, F J
1998-06-01
In this study, we have used radioligand binding and functional techniques to investigate tachykinin receptors in the small intestine of the cane toad Bufo marinus. The radioligand [125I]Bolton-Hunter [Sar9,Met(O2)11]substance P (selective at mammalian NK-1 receptors) showed no specific binding. Specific binding of [125I]Bolton-Hunter substance P ([125I]BHSP) was saturable, of high affinity (Kd 0.3 nM) and was inhibited by SP (IC50 0.64 nM) > ranakinin approximately neurokinin A (NKA) > or = SP(5-11) > or = neuropeptide gamma > or = scyliorhinin II > scyliorhinin I > or = [Sar9]-SP > or = neurokinin B approximately physalaemin approximately carassin > SP(7-11) approximately eledoisin > or = SP(4-11) approximately SP(6-11). Binding was also inhibited by Gpp[NH]p > or = GTPgammaS > App[NH]p, indicating a G-protein coupled receptor. The order of potency of tachykinins and analogues in contracting the isolated lower small intestine was carassin (EC50 1.4 nM) > eledoisin approximately SP > or = physalaemin > or = ranakinin > SP(6-11) > scyliorhinin II > or = neuropeptide gamma > neurokinin B approximately NKA approximately scyliorhinin I > or = SP(4-11) > or = SP(5-11) > [Sar9]SP > SP(7-11). In both studies, the selective mammalian NK-1, NK-2 and NK-3 receptor agonists [Sar9,Met(O2)11]SP, [Lys5,Me-Leu9,Nle10]NKA(4-10) and senktide were weak or ineffective. There was a strong positive correlation between the pD2 and pIC50 values for mammalian tachykinins and analogues (r = 0.907), but not for the non-mammalian tachykinins, which were all full agonists but variable binding competitors. [Sar9,Met(O2)11]-SP(pD2 5.7) was approximately 25-fold less potent as an agonist than [Sar9]SP, which was itself 25-fold weaker than SP. Responses to SP were significantly reduced (n = 8, P<0.001) by the antagonist [D-Arg1,D-Trp7,9,Leu11]-SP (spantide; 1 microM). Highly selective NK-1 receptor antagonists including CP 99994 and GR 82334 (both 1 microM) were ineffective in both functional and binding studies. Tetrodotoxin (1 microM) did not inhibit contractile responses to SP, NKA and senktide. In summary, this study has shown the presence of one or more tachykinin receptor in the toad intestine. The binding site recognised by [125I]BHSP prefers SP and ranakinin. This toad "NK-1-like receptor" differs from the mammalian NK-1 receptor in having a low affinity for all mammalian NK-1 selective ligands, including antagonists. For some non-mammalian peptides, their high potency as contractile agonists relative to their poor binding affinity suggests the existence of other tachykinin receptors in the toad small intestine.
Multifrequency synthetic aperture radar antenna comparison study. [for remote sensing
NASA Technical Reports Server (NTRS)
Blevins, B. A.
1983-01-01
Three multifrequency, dual polarization SAR antenna designs are reviewed. The SAR antenna design specifications were for a "straw man' SAR which would approximate the requirements for projected shuttle-based SAR's. Therefore, the physical dimensions were constrained to be compatible with the space shuttle. The electrical specifications were similar to those of SIR-A and SIR-B with the addition of dual polarization and the addition of C and X band operation. Early in the antenna design considerations, three candidate technologies emerged as having promise. They were: (1) microstrip patch planar array antennas, (2) slotted waveguide planar array antennas, and (3) open-ended waveguide planar array antennas.
Oil Spill detection off the eastern coast of India using Sentinel-1 dual polarimeteric SAR imagery
NASA Astrophysics Data System (ADS)
De, S.; Bhattacharya, A.; Gautam, R.
2017-12-01
Among the various Earth observing sensors, the spaceborne Polarimetric Synthetic Aperture Radar (PolSAR) is considered as one of the most flexible and has been widely used in disaster response applications due to its all-weather illumination independent capability. Sentinel-1 is a two-satellite constellation with a C-band polarimetric Synthetic Aperture Radar (PolSAR) sensor, which provides global coverage with a 12-day repeat cycle in the same acquisition geometry, and the possibility of a 3-day repeat imaging in independent geometry, making it ideal for operational geodynamic monitoring. The proposed study aims to detect changes in polarimetric parameters associated with an oil spill event occurred off the coast of Ennore, Tamil Nadu, India (13.228° N Lon: 80.363° E ) on 28 January 2017. The initial spill covered an area of approximately 7.26 sq. km, spreading to an area of 12.56 sq. km. in a single day. The spread was mainly attributed to the strong shore parallel southerly current. To this end, two PolSAR images were used from before and after the event acquired on 17 and 29 January 2017, respectively in dual-polarimetric (VV,VH) interferometric wide swath mode and with same acquisition geometry. The images are first calibrated, co-registered and terrain corrected to make them comparable in a geo-coordinate framework. A refined Lee speckle filter is applied with a 5x5 window to reduce the influence of coherent speckle. The pair of images are then used to generate a hellinger distance based change index corresponding to each polarimetric channel. The indices are then applied as input to a Convolutional Neural Network (CNN) with the objective of discriminating the areas corresponding to changes due to the oil spill, movement of ships, rough ocean surface etc. The final result is a binary change detection map of the oil spill area. The results obtained were compared with that obtained by survey of the affected oil spill area by the Integrated Coastal and Marine Area Management (ICMAM) Project. A close agreement was found with the results of our SAR-image based classification technique and that published in the event report by the same agency.
Detection of moving humans in UHF wideband SAR
NASA Astrophysics Data System (ADS)
Sjögren, Thomas K.; Ulander, Lars M. H.; Frölind, Per-Olov; Gustavsson, Anders; Stenström, Gunnar; Jonsson, Tommy
2014-06-01
In this paper, experimental results for UHF wideband SAR imaging of humans on an open field and inside a forest is presented. The results show ability to detect the humans and suggest possible ways to improve the results. In the experiment, single channel wideband SAR mode of the UHF UWB system LORA developed by Swedish Defence Research Agency (FOI). The wideband SAR mode used in the experiment was from 220 to 450 MHz, thus with a fractional bandwidth of 0.68. Three humans walking and one stationary were available in the scene with one of the walking humans in the forest. The signature of the human in the forest appeared on the field, due to azimuth shift from the positive range speed component. One human on the field and the one in the forest had approximately the same speed and walking direction. The signatures in the SAR image were compared as a function of integration time based on focusing using the average relative speed of these given by GPS logs. A signal processing gain was obtained for the human in forest until approximately 15 s and 35 s for the human on the field. This difference is likely explained by uneven terrain and trees in the way, causing a non-straight walking path.
Monitoring Building Deformation with InSAR: Experiments and Validation.
Yang, Kui; Yan, Li; Huang, Guoman; Chen, Chu; Wu, Zhengpeng
2016-12-20
Synthetic Aperture Radar Interferometry (InSAR) techniques are increasingly applied for monitoring land subsidence. The advantages of InSAR include high accuracy and the ability to cover large areas; nevertheless, research validating the use of InSAR on building deformation is limited. In this paper, we test the monitoring capability of the InSAR in experiments using two landmark buildings; the Bohai Building and the China Theater, located in Tianjin, China. They were selected as real examples to compare InSAR and leveling approaches for building deformation. Ten TerraSAR-X images spanning half a year were used in Permanent Scatterer InSAR processing. These extracted InSAR results were processed considering the diversity in both direction and spatial distribution, and were compared with true leveling values in both Ordinary Least Squares (OLS) regression and measurement of error analyses. The detailed experimental results for the Bohai Building and the China Theater showed a high correlation between InSAR results and the leveling values. At the same time, the two Root Mean Square Error (RMSE) indexes had values of approximately 1 mm. These analyses show that a millimeter level of accuracy can be achieved by means of InSAR technique when measuring building deformation. We discuss the differences in accuracy between OLS regression and measurement of error analyses, and compare the accuracy index of leveling in order to propose InSAR accuracy levels appropriate for monitoring buildings deformation. After assessing the advantages and limitations of InSAR techniques in monitoring buildings, further applications are evaluated.
Robust Ground Target Detection by SAR and IR Sensor Fusion Using Adaboost-Based Feature Selection
Kim, Sungho; Song, Woo-Jin; Kim, So-Hyun
2016-01-01
Long-range ground targets are difficult to detect in a noisy cluttered environment using either synthetic aperture radar (SAR) images or infrared (IR) images. SAR-based detectors can provide a high detection rate with a high false alarm rate to background scatter noise. IR-based approaches can detect hot targets but are affected strongly by the weather conditions. This paper proposes a novel target detection method by decision-level SAR and IR fusion using an Adaboost-based machine learning scheme to achieve a high detection rate and low false alarm rate. The proposed method consists of individual detection, registration, and fusion architecture. This paper presents a single framework of a SAR and IR target detection method using modified Boolean map visual theory (modBMVT) and feature-selection based fusion. Previous methods applied different algorithms to detect SAR and IR targets because of the different physical image characteristics. One method that is optimized for IR target detection produces unsuccessful results in SAR target detection. This study examined the image characteristics and proposed a unified SAR and IR target detection method by inserting a median local average filter (MLAF, pre-filter) and an asymmetric morphological closing filter (AMCF, post-filter) into the BMVT. The original BMVT was optimized to detect small infrared targets. The proposed modBMVT can remove the thermal and scatter noise by the MLAF and detect extended targets by attaching the AMCF after the BMVT. Heterogeneous SAR and IR images were registered automatically using the proposed RANdom SAmple Region Consensus (RANSARC)-based homography optimization after a brute-force correspondence search using the detected target centers and regions. The final targets were detected by feature-selection based sensor fusion using Adaboost. The proposed method showed good SAR and IR target detection performance through feature selection-based decision fusion on a synthetic database generated by OKTAL-SE. PMID:27447635
Robust Ground Target Detection by SAR and IR Sensor Fusion Using Adaboost-Based Feature Selection.
Kim, Sungho; Song, Woo-Jin; Kim, So-Hyun
2016-07-19
Long-range ground targets are difficult to detect in a noisy cluttered environment using either synthetic aperture radar (SAR) images or infrared (IR) images. SAR-based detectors can provide a high detection rate with a high false alarm rate to background scatter noise. IR-based approaches can detect hot targets but are affected strongly by the weather conditions. This paper proposes a novel target detection method by decision-level SAR and IR fusion using an Adaboost-based machine learning scheme to achieve a high detection rate and low false alarm rate. The proposed method consists of individual detection, registration, and fusion architecture. This paper presents a single framework of a SAR and IR target detection method using modified Boolean map visual theory (modBMVT) and feature-selection based fusion. Previous methods applied different algorithms to detect SAR and IR targets because of the different physical image characteristics. One method that is optimized for IR target detection produces unsuccessful results in SAR target detection. This study examined the image characteristics and proposed a unified SAR and IR target detection method by inserting a median local average filter (MLAF, pre-filter) and an asymmetric morphological closing filter (AMCF, post-filter) into the BMVT. The original BMVT was optimized to detect small infrared targets. The proposed modBMVT can remove the thermal and scatter noise by the MLAF and detect extended targets by attaching the AMCF after the BMVT. Heterogeneous SAR and IR images were registered automatically using the proposed RANdom SAmple Region Consensus (RANSARC)-based homography optimization after a brute-force correspondence search using the detected target centers and regions. The final targets were detected by feature-selection based sensor fusion using Adaboost. The proposed method showed good SAR and IR target detection performance through feature selection-based decision fusion on a synthetic database generated by OKTAL-SE.
DUSTER: demonstration of an integrated LWIR-VNIR-SAR imaging system
NASA Astrophysics Data System (ADS)
Wilson, Michael L.; Linne von Berg, Dale; Kruer, Melvin; Holt, Niel; Anderson, Scott A.; Long, David G.; Margulis, Yuly
2008-04-01
The Naval Research Laboratory (NRL) and Space Dynamics Laboratory (SDL) are executing a joint effort, DUSTER (Deployable Unmanned System for Targeting, Exploitation, and Reconnaissance), to develop and test a new tactical sensor system specifically designed for Tier II UAVs. The system is composed of two coupled near-real-time sensors: EyePod (VNIR/LWIR ball gimbal) and NuSAR (L-band synthetic aperture radar). EyePod consists of a jitter-stabilized LWIR sensor coupled with a dual focal-length optical system and a bore-sighted high-resolution VNIR sensor. The dual focal-length design coupled with precision pointing an step-stare capabilities enable EyePod to conduct wide-area survey and high resolution inspection missions from a single flight pass. NuSAR is being developed with partners Brigham Young University (BYU) and Artemis, Inc and consists of a wideband L-band SAR capable of large area survey and embedded real-time image formation. Both sensors employ standard Ethernet interfaces and provide geo-registered NITFS output imagery. In the fall of 2007, field tests were conducted with both sensors, results of which will be presented.
SAR/multispectral image fusion for the detection of environmental hazards with a GIS
NASA Astrophysics Data System (ADS)
Errico, Angela; Angelino, Cesario Vincenzo; Cicala, Luca; Podobinski, Dominik P.; Persechino, Giuseppe; Ferrara, Claudia; Lega, Massimiliano; Vallario, Andrea; Parente, Claudio; Masi, Giuseppe; Gaetano, Raffaele; Scarpa, Giuseppe; Amitrano, Donato; Ruello, Giuseppe; Verdoliva, Luisa; Poggi, Giovanni
2014-10-01
In this paper we propose a GIS-based methodology, using optical and SAR remote sensing data, together with more conventional sources, for the detection of small cattle breeding areas, potentially responsible of hazardous littering. This specific environmental problem is very relevant for the Caserta area, in southern Italy, where many small buffalo breeding farms exist which are not even known to the productive activity register, and are not easily monitored and surveyed. Experiments on a test area, with available specific ground truth, prove that the proposed systems is characterized by very large detection probability and negligible false alarm rate.
Investigation of ionospheric effects on SAR Interferometry (InSAR): A case study of Hong Kong
NASA Astrophysics Data System (ADS)
Zhu, Wu; Ding, Xiao-Li; Jung, Hyung-Sup; Zhang, Qin; Zhang, Bo-Chen; Qu, Wei
2016-08-01
Synthetic Aperture Radar Interferometry (InSAR) has demonstrated its potential for high-density spatial mapping of ground displacement associated with earthquakes, volcanoes, and other geologic processes. However, this technique may be affected by the ionosphere, which can result in the distortions of Synthetic Aperture Radar (SAR) images, phases, and polarization. Moreover, ionospheric effect has become and is becoming further significant with the increasing interest in low-frequency SAR systems, limiting the further development of InSAR technique. Although some research has been carried out, thorough analysis of ionospheric influence on true SAR imagery is still limited. Based on this background, this study performs a thorough investigation of ionospheric effect on InSAR through processing L-band ALOS-1/PALSAR-1 images and dual-frequency Global Positioning System (GPS) data over Hong Kong, where the phenomenon of ionospheric irregularities often occurs. The result shows that the small-scale ionospheric irregularities can cause the azimuth pixel shifts and phase advance errors on interferograms. Meanwhile, it is found that these two effects result in the stripe-shaped features in InSAR images. The direction of the stripe-shaped effects keep approximately constant in space for our InSAR dataset. Moreover, the GPS-derived rate of total electron content change index (ROTI), an index to reflect the level of ionospheric disturbances, may be a useful indicator for predicting the ionospheric effect for SAR images. This finding can help us evaluate the quality of SAR images when considering the ionospheric effect.
ERIC Educational Resources Information Center
Hubert, Lawrence; Arabie, Phipps; Meulman, Jacqueline
1998-01-01
Introduces a method for fitting order-constrained matrices that satisfy the strongly anti-Robinson restrictions (SAR). The method permits a representation of the fitted values in a (least-squares) SAR approximating matrix as lengths of paths in a graph. The approach is illustrated with a published proximity matrix. (SLD)
Hu, Hongbo; Li, Li; Kao, Richard Y; Kou, Binbin; Wang, Zhanguo; Zhang, Liang; Zhang, Huiyuan; Hao, Zhiyong; Tsui, Wayne H; Ni, Anping; Cui, Lianxian; Fan, Baoxing; Guo, Feng; Rao, Shuan; Jiang, Chengyu; Li, Qian; Sun, Manji; He, Wei; Liu, Gang
2005-01-01
A 10-mer overlapping peptide library has been synthesized for screening and identification of linear B-cell epitopes of severe acute respiratory syndrome associated coronavirus (SARS-CoV), which spanned the major structural proteins of SARS-CoV. One hundred and eleven candidate peptides were positive according to the result of PEPscan, which were assembled into 22 longer peptides. Five of these peptides showed high cross-immunoreactivities (approximately 66.7 to 90.5%) to SARS convalescent patients' sera from the severest epidemic regions of the China mainland. Most interestingly, S(471-503), a peptide located at the receptor binding domain (RBD) of SARS-CoV, could specifically block the binding between the RBD and angiotensin-converting enzyme 2, resulting in the inhibition of SARS-CoV entrance into host cells in vitro. The study demonstrated that S(471-503) peptide was a potential immunoantigen for the development of peptide-based vaccine or a candidate for further drug evaluation against the SARS-CoV virus-cell fusion.
Monitoring Building Deformation with InSAR: Experiments and Validation
Yang, Kui; Yan, Li; Huang, Guoman; Chen, Chu; Wu, Zhengpeng
2016-01-01
Synthetic Aperture Radar Interferometry (InSAR) techniques are increasingly applied for monitoring land subsidence. The advantages of InSAR include high accuracy and the ability to cover large areas; nevertheless, research validating the use of InSAR on building deformation is limited. In this paper, we test the monitoring capability of the InSAR in experiments using two landmark buildings; the Bohai Building and the China Theater, located in Tianjin, China. They were selected as real examples to compare InSAR and leveling approaches for building deformation. Ten TerraSAR-X images spanning half a year were used in Permanent Scatterer InSAR processing. These extracted InSAR results were processed considering the diversity in both direction and spatial distribution, and were compared with true leveling values in both Ordinary Least Squares (OLS) regression and measurement of error analyses. The detailed experimental results for the Bohai Building and the China Theater showed a high correlation between InSAR results and the leveling values. At the same time, the two Root Mean Square Error (RMSE) indexes had values of approximately 1 mm. These analyses show that a millimeter level of accuracy can be achieved by means of InSAR technique when measuring building deformation. We discuss the differences in accuracy between OLS regression and measurement of error analyses, and compare the accuracy index of leveling in order to propose InSAR accuracy levels appropriate for monitoring buildings deformation. After assessing the advantages and limitations of InSAR techniques in monitoring buildings, further applications are evaluated. PMID:27999403
Zhou, Rui; Sun, Jinping; Hu, Yuxin; Qi, Yaolong
2018-01-31
Synthetic aperture radar (SAR) equipped on the hypersonic air vehicle in near space has many advantages over the conventional airborne SAR. However, its high-speed maneuvering characteristics with curved trajectory result in serious range migration, and exacerbate the contradiction between the high resolution and wide swath. To solve this problem, this paper establishes the imaging geometrical model matched with the flight trajectory of the hypersonic platform and the multichannel azimuth sampling model based on the displaced phase center antenna (DPCA) technology. Furthermore, based on the multichannel signal reconstruction theory, a more efficient spectrum reconstruction model using discrete Fourier transform is proposed to obtain the azimuth uniform sampling data. Due to the high complexity of the slant range model, it is difficult to deduce the processing algorithm for SAR imaging. Thus, an approximate range model is derived based on the minimax criterion, and the optimal second-order approximate coefficients of cosine function are obtained using the two-population coevolutionary algorithm. On this basis, aiming at the problem that the traditional Omega-K algorithm cannot compensate the residual phase with the difficulty of Stolt mapping along the range frequency axis, this paper proposes an Exact Transfer Function (ETF) algorithm for SAR imaging, and presents a method of range division to achieve wide swath imaging. Simulation results verify the effectiveness of the ETF imaging algorithm.
Zhou, Rui; Hu, Yuxin; Qi, Yaolong
2018-01-01
Synthetic aperture radar (SAR) equipped on the hypersonic air vehicle in near space has many advantages over the conventional airborne SAR. However, its high-speed maneuvering characteristics with curved trajectory result in serious range migration, and exacerbate the contradiction between the high resolution and wide swath. To solve this problem, this paper establishes the imaging geometrical model matched with the flight trajectory of the hypersonic platform and the multichannel azimuth sampling model based on the displaced phase center antenna (DPCA) technology. Furthermore, based on the multichannel signal reconstruction theory, a more efficient spectrum reconstruction model using discrete Fourier transform is proposed to obtain the azimuth uniform sampling data. Due to the high complexity of the slant range model, it is difficult to deduce the processing algorithm for SAR imaging. Thus, an approximate range model is derived based on the minimax criterion, and the optimal second-order approximate coefficients of cosine function are obtained using the two-population coevolutionary algorithm. On this basis, aiming at the problem that the traditional Omega-K algorithm cannot compensate the residual phase with the difficulty of Stolt mapping along the range frequency axis, this paper proposes an Exact Transfer Function (ETF) algorithm for SAR imaging, and presents a method of range division to achieve wide swath imaging. Simulation results verify the effectiveness of the ETF imaging algorithm. PMID:29385059
Synthetic aperture radar image formation for the moving-target and near-field bistatic cases
NASA Astrophysics Data System (ADS)
Ding, Yu
This dissertation addresses topics in two areas of synthetic aperture radar (SAR) image formation: time-frequency based SAR imaging of moving targets and a fast backprojection (BP) algorithm for near-field bistatic SAR imaging. SAR imaging of a moving target is a challenging task due to unknown motion of the target. We approach this problem in a theoretical way, by analyzing the Wigner-Ville distribution (WVD) based SAR imaging technique. We derive approximate closed-form expressions for the point-target response of the SAR imaging system, which quantify the image resolution, and show how the blurring in conventional SAR imaging can be eliminated, while the target shift still remains. Our analyses lead to accurate prediction of the target position in the reconstructed images. The derived expressions also enable us to further study additional aspects of WVD-based SAR imaging. Bistatic SAR imaging is more involved than the monostatic SAR case, because of the separation of the transmitter and the receiver, and possibly the changing bistatic geometry. For near-field bistatic SAR imaging, we develop a novel fast BP algorithm, motivated by a newly proposed fast BP algorithm in computer tomography. First we show that the BP algorithm is the spatial-domain counterpart of the benchmark o -- k algorithm in bistatic SAR imaging, yet it avoids the frequency-domain interpolation in the o -- k algorithm, which may cause artifacts in the reconstructed image. We then derive the band-limited property for BP methods in both monostatic and bistatic SAR imaging, which is the basis for developing the fast BP algorithm. We compare our algorithm with other frequency-domain based algorithms, and show that it achieves better reconstructed image quality, while having the same computational complexity as that of the frequency-domain based algorithms.
Lee, W M; Gelvich, E A; van der Baan, P; Mazokhin, V N; van Rhoon, G C
2004-09-01
The electrical performance of the CFMA-12 operating at 433 MHz is assessed under laboratory conditions using a RF network analyser. From measurements of the scattering parameters of the CFMA-12 on both a multi-layered muscle- and fat/muscle-equivalent phantom, the optimal water bolus thickness, at which the transfer of the energy to the phantom configuration is maximal, is determined to be approximately 1 cm. The SAR distribution of the CFMA-12 in a multi-layered muscle-equivalent phantom is characterized using Schottky diode sheets and a TVS-600 IR camera. From the SAR measurements using the Schottky diode sheets it is shown that the contribution of the E(x) component to the SAR (SAR(x)) is maximal 7% of the contribution of the E(y)component to the SAR (SAR(y)) at different layers in both phantom configurations. The complete SAR distribution (SAR(tot)) at different depths is measured using the power pulse technique. From these measurements, it can be seen that SAR(y)at a depth of 0 cm in the muscle-equivalent phantom represents up to 80% of SAR(tot). At 1 and 2 cm depth, SAR(y) is up to 95% of SAR(tot). Therefore, in homogeneous muscle-equivalent phantoms, E(y) is the largest E-field component and measurement of SAR(y) distribution is sufficient to characterize SAR-steering performance of the CFMA-12. SAR steering measurements at 1 cm depth in the muscle-equivalent phantom show that the SAR maximum varies by 40% (1 SD) around the average value of 38.8 W kg(-1) (range 10-65 W kg(-1)) between single antenna elements. The effective fieldsize (E(50)) varies by 14% (1 SD) around the average value of 19.1 cm(2).
NASA Astrophysics Data System (ADS)
Lahiri, B. B.; Ranoo, Surojit; Philip, John
2017-11-01
Magnetic fluid hyperthermia (MFH) is becoming a viable cancer treatment methodology where the alternating magnetic field induced heating of magnetic fluid is utilized for ablating the cancerous cells or making them more susceptible to the conventional treatments. The heating efficiency in MFH is quantified in terms of specific absorption rate (SAR), which is defined as the heating power generated per unit mass. In majority of the experimental studies, SAR is evaluated from the temperature rise curves, obtained under non-adiabatic experimental conditions, which is prone to various thermodynamic uncertainties. A proper understanding of the experimental uncertainties and its remedies is a prerequisite for obtaining accurate and reproducible SAR. Here, we study the thermodynamic uncertainties associated with peripheral heating, delayed heating, heat loss from the sample and spatial variation in the temperature profile within the sample. Using first order approximations, an adiabatic reconstruction protocol for the measured temperature rise curves is developed for SAR estimation, which is found to be in good agreement with those obtained from the computationally intense slope corrected method. Our experimental findings clearly show that the peripheral and delayed heating are due to radiation heat transfer from the heating coils and slower response time of the sensor, respectively. Our results suggest that the peripheral heating is linearly proportional to the sample area to volume ratio and coil temperature. It is also observed that peripheral heating decreases in presence of a non-magnetic insulating shielding. The delayed heating is found to contribute up to ~25% uncertainties in SAR values. As the SAR values are very sensitive to the initial slope determination method, explicit mention of the range of linear regression analysis is appropriate to reproduce the results. The effect of sample volume to area ratio on linear heat loss rate is systematically studied and the results are compared using a lumped system thermal model. The various uncertainties involved in SAR estimation are categorized as material uncertainties, thermodynamic uncertainties and parametric uncertainties. The adiabatic reconstruction is found to decrease the uncertainties in SAR measurement by approximately three times. Additionally, a set of experimental guidelines for accurate SAR estimation using adiabatic reconstruction protocol is also recommended. These results warrant a universal experimental and data analysis protocol for SAR measurements during field induced heating of magnetic fluids under non-adiabatic conditions.
Modeling Wetland Vegetation using Polarimetric SAR
NASA Technical Reports Server (NTRS)
Slatton, K. Clint; Crawford, Melba M.; Gibeaut, James C.; Gutierrez, Roberto O.
1996-01-01
A three-year project to study small-scale topographic changes and relict geomorphic features on barrier islands using synthetic aperture radar (SAR) is described. A study area on the Texas coast consisting of Galveston Island and Bolivar Peninsula was overflown by the NASA/JPL DC 8 AIRSAR in April 1995. Data was acquired in the fully polarimetric mode using C-, L-, and P-bands and in the TOPSAR configuration with C- and L-bands in interferometric mode. The study area will be overflown again in late spring 1996. The data will be registered to global positioning system (GPS) surveyed points to form high resolution digital elevation models (DEM) and then analyzed to investigate possible topographic changes.
Novel active signal compression in low-noise analog readout at future X-ray FEL facilities
NASA Astrophysics Data System (ADS)
Manghisoni, M.; Comotti, D.; Gaioni, L.; Lodola, L.; Ratti, L.; Re, V.; Traversi, G.; Vacchi, C.
2015-04-01
This work presents the design of a low-noise front-end implementing a novel active signal compression technique. This feature can be exploited in the design of analog readout channels for application to the next generation free electron laser (FEL) experiments. The readout architecture includes the low-noise charge sensitive amplifier (CSA) with dynamic signal compression, a time variant shaper used to process the signal at the preamplifier output and a 10-bit successive approximation register (SAR) analog-to-digital converter (ADC). The channel will be operated in such a way to cope with the high frame rate (exceeding 1 MHz) foreseen for future XFEL machines. The choice of a 65 nm CMOS technology has been made in order to include all the building blocks in the target pixel pitch of 100 μm. This work has been carried out in the frame of the PixFEL Project funded by the Istituto Nazionale di Fisica Nucleare (INFN), Italy.
Identifying Corresponding Patches in SAR and Optical Images With a Pseudo-Siamese CNN
NASA Astrophysics Data System (ADS)
Hughes, Lloyd H.; Schmitt, Michael; Mou, Lichao; Wang, Yuanyuan; Zhu, Xiao Xiang
2018-05-01
In this letter, we propose a pseudo-siamese convolutional neural network (CNN) architecture that enables to solve the task of identifying corresponding patches in very-high-resolution (VHR) optical and synthetic aperture radar (SAR) remote sensing imagery. Using eight convolutional layers each in two parallel network streams, a fully connected layer for the fusion of the features learned in each stream, and a loss function based on binary cross-entropy, we achieve a one-hot indication if two patches correspond or not. The network is trained and tested on an automatically generated dataset that is based on a deterministic alignment of SAR and optical imagery via previously reconstructed and subsequently co-registered 3D point clouds. The satellite images, from which the patches comprising our dataset are extracted, show a complex urban scene containing many elevated objects (i.e. buildings), thus providing one of the most difficult experimental environments. The achieved results show that the network is able to predict corresponding patches with high accuracy, thus indicating great potential for further development towards a generalized multi-sensor key-point matching procedure. Index Terms-synthetic aperture radar (SAR), optical imagery, data fusion, deep learning, convolutional neural networks (CNN), image matching, deep matching
SARS-CoV and Emergent Coronaviruses: Viral Determinants of Interspecies Transmission
Bolles, Meagan; Donaldson, Eric; Baric, Ralph
2011-01-01
Most new emerging viruses are derived from strains circulating in zoonotic reservoirs. Coronaviruses, which had an established potential for cross-species transmission within domesticated animals, suddenly became relevant with the unexpected emergence of the highly pathogenic human SARS-CoV strain from zoonotic reservoirs in 2002. SARS-CoV infected approximately 8000 people worldwide before public health measures halted the epidemic. Supported by robust time-ordered sequence variation, structural biology, well-characterized patient pools, and biological data, the emergence of SARS-CoV represents one of the best studied natural models of viral disease emergence from zoonotic sources. This review article summarizes previous and more recent advances into the molecular and structural characteristics, with particular emphasis on host-receptor interactions, that drove this remarkable virus disease outbreak in human populations. PMID:22180768
SAR Imaging through the Earth’s Ionosphere
2013-11-06
or, otherwise, if polarimetry puts too high of a demand on storage, downlink capacity, etc.), then the approach based on the Faraday rotation is not...reflected fields for both are the same in the first Born approximation. Modern practical applications of radar polarimetry employ different empirical and...Fruneau, and J.-P. Rudant. Classification of tropical vegetation using multifrequency partial SAR polarimetry . IEEE Geoscience and Remote Sensing Letters
Evaluation of SAR in a human body model due to wireless power transmission in the 10 MHz band.
Laakso, Ilkka; Tsuchida, Shogo; Hirata, Akimasa; Kamimura, Yoshitsugu
2012-08-07
This study discusses a computational method for calculating the specific absorption rate (SAR) due to a wireless power transmission system in the 10 MHz frequency band. A two-step quasi-static method comprised of the method of moments and the scalar potential finite-difference method are proposed. The applicability of the quasi-static approximation for localized exposure in this frequency band is discussed by comparing the SAR in a lossy dielectric cylinder computed with a full-wave electromagnetic analysis and the quasi-static approximation. From the computational results, the input impedance of the resonant coils was affected by the existence of the cylinder. On the other hand, the magnetic field distribution in free space and considering the cylinder and an impedance matching circuit were in good agreement; the maximum difference in the amplitude of the magnetic field was 4.8%. For a cylinder-coil distance of 10 mm, the difference between the peak 10 g averaged SAR in the cylinder computed with the full-wave electromagnetic method and our quasi-static method was 7.8%. These results suggest that the quasi-static approach is applicable for conducting the dosimetry of wireless power transmission in the 10 MHz band. With our two-step quasi-static method, the SAR in the anatomically based model was computed for different exposure scenarios. From those computations, the allowable input power satisfying the limit of a peak 10 g averaged SAR of 2.0 W kg(-1) was 830 W in the worst case exposure scenario with a coil positioned at a distance of 30 mm from the chest.
Li, Ling; Gu, Jiang; Shi, Xicheng; Gong, Encong; Li, Xingwang; Shao, Hongquan; Shi, Xueying; Jiang, Huijun; Gao, Xiaoqiang; Cheng, Daiyun; Guo, Lizhu; Wang, Hao; Shi, Xiaohong; Wang, Peizhi; Zhang, Qianying; Shen, Bing
2005-09-15
During the outbreak of the emergent severe acute respiratory syndrome (SARS) infection, >30% of the approximately 8000 infected persons were health care workers. The highly infectious nature of SARS coronavirus (SARS-CoV) compelled our pathologists to consider biosafety issues in the autopsy room and for tissue processing procedures. A specially designed biosafety level 3 (BSL-3) autopsy laboratory was constructed and divided into a clean area, a semicontaminated area, a contaminated area, and 2 buffer zones. High-efficiency particulate air filters were placed in the air supply and exhaust systems. Laminar air flow was from the clean areas to the less clean areas. The negative pressures of the contaminated, semicontaminated, and clean areas were approximately -50 pa, -25 pa, and -5 pa, respectively. Personal protective equipment, including gas mask, impermeable protective clothing, and 3 layers of gloves worn during autopsies; the equipment was decontaminated before it was allowed to exit the facility. Strict BSL-3 practices were followed. When a given concentration of particulate sarin simulant was introduced into the contaminated area, it could not be detected in either the semicontaminated area or clean area, and particles >0.3 microm in size were not detected in the exhaust air. A total of 16 complete postmortem examinations for probable and suspected SARS were performed during a 2-month period. Of these, 7 reported confirmed cases of SARS. None of the 23 pathologists and technicians who participated in these autopsies was infected with SARS-CoV. Our experience suggests that BSL-3 laboratory operating principles should be among the special requirements for performing autopsies of contaminated bodies and that they can safeguard the clinicians and the environment involved in these procedures.
Hirata, Akimasa; Yanase, Kazuya; Laakso, Ilkka; Chan, Kwok Hung; Fujiwara, Osamu; Nagaoka, Tomoaki; Watanabe, Soichi; Conil, Emmanuelle; Wiart, Joe
2012-12-21
According to the international guidelines, the whole-body averaged specific absorption rate (WBA-SAR) is used as a metric of basic restriction for radio-frequency whole-body exposure. It is well known that the WBA-SAR largely depends on the frequency of the incident wave for a given incident power density. The frequency at which the WBA-SAR becomes maximal is called the 'resonance frequency'. Our previous study proposed a scheme for estimating the WBA-SAR at this resonance frequency based on an analogy between the power absorption characteristic of human models in free space and that of a dipole antenna. However, a scheme for estimating the WBA-SAR in a grounded human has not been discussed sufficiently, even though the WBA-SAR in a grounded human is larger than that in an ungrounded human. In this study, with the use of the finite-difference time-domain method, the grounded condition is confirmed to be the worst-case exposure for human body models in a standing posture. Then, WBA-SARs in grounded human models are calculated at their respective resonant frequencies. A formula for estimating the WBA-SAR of a human standing on the ground is proposed based on an analogy with a quarter-wavelength monopole antenna. First, homogenized human body models are shown to provide the conservative WBA-SAR as compared with anatomically based models. Based on the formula proposed here, the WBA-SARs in grounded human models are approximately 10% larger than those in free space. The variability of the WBA-SAR was shown to be ±30% even for humans of the same age, which is caused by the body shape.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-29
..., Federal Register notice they may be inspected, between 10 a.m. and 4 p.m., in the FinCEN reading room in...-Filing, which is provided free of charge, offers streamlined BSA information submission; faster routing... suspicious activity report (SAR) was received; Feedback reports to filers; Faster acknowledgement to money...
Pascazio, Vito; Schirinzi, Gilda
2002-01-01
In this paper, a technique that is able to reconstruct highly sloped and discontinuous terrain height profiles, starting from multifrequency wrapped phase acquired by interferometric synthetic aperture radar (SAR) systems, is presented. We propose an innovative unwrapping method, based on a maximum likelihood estimation technique, which uses multifrequency independent phase data, obtained by filtering the interferometric SAR raw data pair through nonoverlapping band-pass filters, and approximating the unknown surface by means of local planes. Since the method does not exploit the phase gradient, it assures the uniqueness of the solution, even in the case of highly sloped or piecewise continuous elevation patterns with strong discontinuities.
Lundgren, Paul; Lu, Zhong
2006-01-01
We analyzed RADARSAT-1 synthetic aperture radar (SAR) data to compute interferometric SAR (InSAR) images of surface deformation at Uzon caldera, Kamchatka, Russia. From 2000 to 2003 approximately 0.15 m of inflation occurred at Uzon caldera, extending beneath adjacent Kikhpinych volcano. This contrasts with InSAR data showing no significant deformation during either the 1999 to 2000, or 2003 to 2004, time periods. We performed three sets of numerical source inversions to fit InSAR data from three different swaths spanning 2000 to 2003. The preferred source model is an irregularly shaped, pressurized crack, dipping ∼20° to the NW, 4 km below the surface. The geometry of this solution is similar to the upper boundary of the geologically inferred magma chamber. Extension of the surface deformation and source to adjacent Kikhpinych volcano, without an eruption, suggests that the deformation is more likely of hydrothermal origin, possibly driven by recharge of the magma chamber.
NASA Astrophysics Data System (ADS)
Mirzaee, S.; Motagh, M.; Akbari, B.
2017-05-01
Shabkola is a village located in Mazandaran province of northern Iran that suffers from the mass movement happening in the upstream. Deforestation and changes to land use are the main reasons for the soil instability in this region, which together with steep slope, relatively high precipitation rate and natural erosion has led to such a condition. The area of mass movement is approximately 90 hectares which is a big threat for people living in the region. In this study, we have utilized two different geodetic techniques including InSAR time-series analysis and GPS measurements to assess slope stability in Shabkola. The SAR dataset includes 19 ALOS/PALSAR images spanning from July 2007 to February 2011 while GPS observations are collected in 5 campaigns from September 2011 to May 2014. Displacement as much as approximately 11.7 m in slope direction was detected by GPS observations for the 2011-2014 time period. Most of the slope geometry is in north-south direction, for which the sensitivity of InSAR for displacement detection is low. However, ALOS PALSAR data analysis revealed a previously unknown landslide, covered by dense vegetation in the northern part of main Shabkola landslide, showing line-of-sight velocity of approximately 2cm/year in the time period 2007-2011.
Lew, R; Geraghty, D P; Drapeau, G; Regoli, D; Burcher, E
1990-08-02
The selective tachykinin agonist [Sar9,Met(O2)11]substance P (Sar-SP) was radioiodinated with [125I]Bolton-Hunter reagent and the product [125I]Bolton-Hunter-[Sar9,Met(O)2)11]SP (BHSar-SP) purified using reverse phase HPLC. Autoradiographic studies showed dense specific binding of BHSar-SP over the rat submandibular gland and over several regions in rat brain, with very low nonspecific binding, identical with the pattern of binding sites seen in a parallel study with [125I]Bolton-Hunter SP (BHSP). In homogenate binding experiments, BHSar-SP bound with high affinity to a single site in membranes from rat brain (KD 261 pM) and rat submandibular gland (KD 105 pM). Comparative values for BHSP were 495 and 456 pM, i.e. of two and four fold lower affinity than BHSar-SP. Association of BHSar-SP to membranes from brain (k+1 3.7 x 10(9) M-1 min-1) was faster than to membranes from salivary gland (k+1 5.6 x 10(8) M-1 min-1). In competition studies, BHSar-SP was displaced from salivary gland membranes by substance P (SP) approximately physalaemin greater than or equal to Sar-SP approximately SP-(3-11) greater than SP-(5-11) much greater than neurokinin A (NKA) approximately eledoisin = kassinin = SP-methyl ester greater than or equal to neurokinin B (NKB) much greater than [Nle10]NKA-(4-10) greater than [MePhe7]NKB-(4-10). In brain membranes, the rank potency order was SP greater than Sar-SP greater than or equal to physalaemin greater than SP-(3-11) greater than SP-(5-11) greater than NKA greater than or equal to eledoisin much greater than NKB greater than kassinin greater than SP-methyl ester: however [MePhe7]NKB-(4-10) and [Nle10]NKA-(4-10) were ineffective competitors at concentrations up to 1 microM. Both binding patterns are consistent with BHSar-SP binding to an NK1 site. With the exception of SP, Sar-SP, SP-(3-11) and physalaemin, all competitors were 5 to 54 times less potent at BHSar-SP binding sites in brain than in salivary gland. These data reveal some differences in characteristics of NK1 binding sites in brain and submandibular gland. Although of higher affinity, BHSar-SP does not appear greatly more selective than BHSP in its ability to define NK1 binding sites.
Techniques in processing multi-frequency multi-polarization spaceborne SAR data
NASA Technical Reports Server (NTRS)
Curlander, John C.; Chang, C. Y.
1991-01-01
This paper presents the algorithm design of the SIR-C ground data processor, with emphasis on the unique elements involved in the production of registered multifrequency polarimetric data products. A quick-look processing algorithm used for generation of low-resolution browse image products and estimation of echo signal parameters is also presented. Specifically the discussion covers: (1) azimuth reference function generation to produce registered polarimetric imagery; (2) geometric rectification to accommondate cross-track and along-track Doppler drifts; (3) multilook filtering designed to generate output imagery with a uniform resolution; and (4) efficient coding to compress the polarimetric image data for distribution.
Witteman, Holly O; Bouck, Zachary; Bravo, Caroline A; Desveaux, Laura; Llovet, Diego; Presseau, Justin; Saragosa, Marianne; Taljaard, Monica; Umar, Shama; Grimshaw, Jeremy M; Tinmouth, Jill; Ivers, Noah M
2018-01-01
Background Cancer Care Ontario’s Screening Activity Report (SAR) is an online audit and feedback tool designed to help primary care physicians in Ontario, Canada, identify patients who are overdue for cancer screening or have abnormal results requiring follow-up. Use of the SAR is associated with increased screening rates. To encourage SAR use, Cancer Care Ontario sends monthly emails to registered primary care physicians announcing that updated data are available. However, analytics reveal that 50% of email recipients do not open the email and less than 7% click the embedded link to log in to their report. Objective The goal of the study is to determine whether rewritten emails result in increased log-ins. This manuscript describes how different user- and theory-informed messages intended to improve the impact of the monthly emails will be experimentally tested and how a process evaluation will explore why and how any effects observed were (or were not) achieved. Methods A user-centered approach was used to rewrite the content of the monthly email, including messages operationalizing 3 behavior change techniques: anticipated regret, material incentive (behavior), and problem solving. A pragmatic, 2x2x2 factorial experiment within a multiphase optimization strategy will test the redesigned emails with an embedded qualitative process evaluation to understand how and why the emails may or may not have worked. Trial outcomes will be ascertained using routinely collected administrative data. Physicians will be recruited for semistructured interviews using convenience and snowball sampling. Results As of April 2017, 5576 primary care physicians across the province of Ontario, Canada, had voluntarily registered for the SAR, and in so doing, signed up to receive the monthly email updates. From May to August 2017 participants received the redesigned monthly emails with content specific to their allocated experimental condition prompting use of the SAR. We have not yet begun analyses. Conclusions This study will inform how to communicate effectively with primary care providers by email and identify which behavior change techniques tested are most effective at encouraging engagement with an audit and feedback report. Trial Registration ClinicalTrials.gov NCT03124316; https://clinicaltrials.gov/ct2/show/NCT03124316 (Archived by WebCite at http://www.webcitation.org/6w2MqDWGu) PMID:29453190
InSAR Monitoring of Landslides using RADARSAT and Alos
NASA Astrophysics Data System (ADS)
Singhroy, V.; Pierre-Jean, A.; Pavlic, G.
2009-05-01
We present the results of InSAR monitoring of several landslides using RADARDAT, and ALOS satellites. InSAR techniques are increasingly being used in slope stability assessment. Our research has shown that differential InSAR and coherent target monitoring techniques using field corner reflectors are useful to monitor landslide activity along strategic transportation and energy corridors. The Mackenzie Valley in northern Canada is experiencing one of the highest rates on mean annual air temperature for any region in Canada, thereby triggering melting in the permafrost, which results in active layer detachment slides. There are approximately 2000 landslides along the proposed Mackenzie Valley pipeline route. In addition, the Trans Canada Highway in the Canadian Rockies are affected by several rock avalanches and slow retrogressive slides. The ALOS PALSAR InSAR results show that we can observe deformation on both vegetated and exposed rock areas on the Little Smokey slide and the Frank Slide. RADARSAT-1 InSAR images indicate the different level of activity of the slopes (large and small) during different periods of the year. RADARSAT-2 is providing the high resolution rapid revisit capabilities needed to continuously monitor these active slopes along Canadian strategic energy and transportation corridors. The information produced by our InSAR activity maps on various landslides are used to realign the pipeline route in sensitive permafrost areas, and to install slope stability measures along the Trans-Canada and Provincial Highways. Using these different satellites we are able to develop guidelines for more reliable uses of these SAR missions Keywords: InSAR, landslides, RADARSAT, ALOS .
A data compression technique for synthetic aperture radar images
NASA Technical Reports Server (NTRS)
Frost, V. S.; Minden, G. J.
1986-01-01
A data compression technique is developed for synthetic aperture radar (SAR) imagery. The technique is based on an SAR image model and is designed to preserve the local statistics in the image by an adaptive variable rate modification of block truncation coding (BTC). A data rate of approximately 1.6 bit/pixel is achieved with the technique while maintaining the image quality and cultural (pointlike) targets. The algorithm requires no large data storage and is computationally simple.
NASA Astrophysics Data System (ADS)
Hammann, Mark Gregory
The fusion of electro-optical (EO) multi-spectral satellite imagery with Synthetic Aperture Radar (SAR) data was explored with the working hypothesis that the addition of multi-band SAR will increase the land-cover (LC) classification accuracy compared to EO alone. Three satellite sources for SAR imagery were used: X-band from TerraSAR-X, C-band from RADARSAT-2, and L-band from PALSAR. Images from the RapidEye satellites were the source of the EO imagery. Imagery from the GeoEye-1 and WorldView-2 satellites aided the selection of ground truth. Three study areas were chosen: Wad Medani, Sudan; Campinas, Brazil; and Fresno- Kings Counties, USA. EO imagery were radiometrically calibrated, atmospherically compensated, orthorectifed, co-registered, and clipped to a common area of interest (AOI). SAR imagery were radiometrically calibrated, and geometrically corrected for terrain and incidence angle by converting to ground range and Sigma Naught (?0). The original SAR HH data were included in the fused image stack after despeckling with a 3x3 Enhanced Lee filter. The variance and Gray-Level-Co-occurrence Matrix (GLCM) texture measures of contrast, entropy, and correlation were derived from the non-despeckled SAR HH bands. Data fusion was done with layer stacking and all data were resampled to a common spatial resolution. The Support Vector Machine (SVM) decision rule was used for the supervised classifications. Similar LC classes were identified and tested for each study area. For Wad Medani, nine classes were tested: low and medium intensity urban, sparse forest, water, barren ground, and four agriculture classes (fallow, bare agricultural ground, green crops, and orchards). For Campinas, Brazil, five generic classes were tested: urban, agriculture, forest, water, and barren ground. For the Fresno-Kings Counties location 11 classes were studied: three generic classes (urban, water, barren land), and eight specific crops. In all cases the addition of SAR to EO resulted in higher overall classification accuracies. In many cases using more than a single SAR band also improved the classification accuracy. There was no single best SAR band for all cases; for specific study areas or LC classes, different SAR bands were better. For Wad Medani, the overall accuracy increased nearly 25% over EO by using all three SAR bands and GLCM texture. For Campinas, the improvement over EO was 4.3%; the large areas of vegetation were classified by EO with good accuracy. At Fresno-Kings Counties, EO+SAR fusion improved the overall classification accuracy by 7%. For times or regions where EO is not available due to extended cloud cover, classification with SAR is often the only option; note that SAR alone typically results in lower classification accuracies than when using EO or EO-SAR fusion. Fusion of EO and SAR was especially important to improve the separability of orchards from other crops, and separating urban areas with buildings from bare soil; those classes are difficult to accurately separate with EO. The outcome of this dissertation contributes to the understanding of the benefits of combining data from EO imagery with different SAR bands and SAR derived texture data to identify different LC classes. In times of increased public and private budget constraints and industry consolidation, this dissertation provides insight as to which band packages could be most useful for increased accuracy in LC classification.
Sedimentary Environments Mapping in the Yellow Sea Using TanDEM-X and Optic Satellites
NASA Astrophysics Data System (ADS)
Ryu, J. H.; Lee, Y. K.; Kim, S. W.
2017-12-01
Due to land reclamation and dredging, 57% of China's coastal wetlands have disappeared since the 1950s, and the total area of tidal flats in South Korea decreased from approximately 2,800km2 in 1990 to 2392km2 in 2005(Qiu, 2011 and MLTM, 2010). Intertidal DEM and sedimentary facies are useful for understanding intertidal functions and monitoring their response to natural and anthropogenic actions. Highly accurate intertidal DEMs with 5-m resolution were generated based on the TanDEM-X interferometric SAR (InSAR) technique because TanDEM-X allows the acquisition of the coherent InSAR pairs with no time lag or approximately 10-second temporal baseline between master and slave SAR image. We successfully generated intertidal zone DEMs with 5-7-m spatial resolutions and interferometric height accuracies better than 0.15 m for three representative tidal flats on the west coast of the Korean Peninsula and one site of chinese coastal region in the Yellow Sea. Surface sediment classification based on remotely sensed data must circumspectly consider an effective critical grain size, water content, local topography, and intertidal structures. The earlier studies have some limitation that the classification map is not considered to analysis various environmental conditions. Therefore, the purpose of this study was minutely to mapping the surface sedimentary facies by analyzing the tidal channel, topography with multi-sensor remotely sensed data and in-situ data.
An RF dosimeter for independent SAR measurement in MRI scanners
DOE Office of Scientific and Technical Information (OSTI.GOV)
Qian, Di; Bottomley, Paul A.; El-Sharkawy, AbdEl-Monem M.
2013-12-15
Purpose: The monitoring and management of radio frequency (RF) exposure is critical for ensuring magnetic resonance imaging (MRI) safety. Commercial MRI scanners can overestimate specific absorption rates (SAR) and improperly restrict clinical MRI scans or the application of new MRI sequences, while underestimation of SAR can lead to tissue heating and thermal injury. Accurate scanner-independent RF dosimetry is essential for measuring actual exposure when SAR is critical for ensuring regulatory compliance and MRI safety, for establishing RF exposure while evaluating interventional leads and devices, and for routine MRI quality assessment by medical physicists. However, at present there are no scanner-independentmore » SAR dosimeters. Methods: An SAR dosimeter with an RF transducer comprises two orthogonal, rectangular copper loops and a spherical MRI phantom. The transducer is placed in the magnet bore and calibrated to approximate the resistive loading of the scanner's whole-body birdcage RF coil for human subjects in Philips, GE and Siemens 3 tesla (3T) MRI scanners. The transducer loop reactances are adjusted to minimize interference with the transmit RF field (B{sub 1}) at the MRI frequency. Power from the RF transducer is sampled with a high dynamic range power monitor and recorded on a computer. The deposited power is calibrated and tested on eight different MRI scanners. Whole-body absorbed power vs weight and body mass index (BMI) is measured directly on 26 subjects. Results: A single linear calibration curve sufficed for RF dosimetry at 127.8 MHz on three different Philips and three GE 3T MRI scanners. An RF dosimeter operating at 123.2 MHz on two Siemens 3T scanners required a separate transducer and a slightly different calibration curve. Measurement accuracy was ∼3%. With the torso landmarked at the xiphoid, human adult whole‑body absorbed power varied approximately linearly with patient weight and BMI. This indicates that whole-body torso SAR is on average independent of the imaging subject, albeit with fluctuations. Conclusions: Our 3T RF dosimeter and transducers accurately measure RF exposure in body-equivalent loads and provide scanner-independent assessments of whole-body RF power deposition for establishing safety compliance useful for MRI sequence and device testing.« less
Mobile phone types and SAR characteristics of the human brain.
Lee, Ae-Kyoung; Hong, Seon-Eui; Kwon, Jong-Hwa; Choi, Hyung-Do; Cardis, Elisabeth
2017-04-07
Mobile phones differ in terms of their operating frequency, outer shape, and form and location of the antennae, all of which affect the spatial distributions of their electromagnetic field and the level of electromagnetic absorption in the human head or brain. For this paper, the specific absorption rate (SAR) was calculated for four anatomical head models at different ages using 11 numerical phone models of different shapes and antenna configurations. The 11 models represent phone types accounting for around 86% of the approximately 1400 commercial phone models released into the Korean market since 2002. Seven of the phone models selected have an internal dual-band antenna, and the remaining four possess an external antenna. Each model was intended to generate an average absorption level equivalent to that of the same type of commercial phone model operating at the maximum available output power. The 1 g peak spatial SAR and ipsilateral and contralateral brain-averaged SARs were reported for all 11 phone models. The effects of the phone type, phone position, operating frequency, and age of head models on the brain SAR were comprehensively determined.
Mobile phone types and SAR characteristics of the human brain
NASA Astrophysics Data System (ADS)
Lee, Ae-Kyoung; Hong, Seon-Eui; Kwon, Jong-Hwa; Choi, Hyung-Do; Cardis, Elisabeth
2017-04-01
Mobile phones differ in terms of their operating frequency, outer shape, and form and location of the antennae, all of which affect the spatial distributions of their electromagnetic field and the level of electromagnetic absorption in the human head or brain. For this paper, the specific absorption rate (SAR) was calculated for four anatomical head models at different ages using 11 numerical phone models of different shapes and antenna configurations. The 11 models represent phone types accounting for around 86% of the approximately 1400 commercial phone models released into the Korean market since 2002. Seven of the phone models selected have an internal dual-band antenna, and the remaining four possess an external antenna. Each model was intended to generate an average absorption level equivalent to that of the same type of commercial phone model operating at the maximum available output power. The 1 g peak spatial SAR and ipsilateral and contralateral brain-averaged SARs were reported for all 11 phone models. The effects of the phone type, phone position, operating frequency, and age of head models on the brain SAR were comprehensively determined.
Merging of an EET CInSAR DEM with the SRTM DEM
NASA Astrophysics Data System (ADS)
Wegmuller, Urs; Wiesmann, Andreas; Santoro, Maurizio
2010-03-01
Cross-interferometry (CInSAR) using ERS-2 and ENVISAT ASAR SAR data acquired in the ERS like mode IS2 at VV-polarization with perpendicular baselines of approximately 2 kilometers permits generation of digital elevation models (DEMs). Thanks to the long perpendicular baselines CInSAR has a good potential to generate accurate DEMs over relatively flat terrain. Over sloped terrain the topographic phase gradients get very high and the signals decorrelate if the carrier frequency difference and the baseline effects do not compensate any more. As a result phase unwrapping gets very difficult so that often no reliable solution is obtained for hilly terrain, resulting in DEMs with significant spatial gaps.Spatial gaps in ERS-2 ENVISAT Tandem (EET) CInSAR DEMs over hilly terrain are clearly an important limitation to the utility of these DEMs. On the other hand the high quality achieved over relatively flat terrain is of high interest. As an attempt to significantly improve the utility of the "good information" contained in the CInSAR DEM we developed a methodology to merge a CInSAR DEM with another available DEM, e.g. the SRTM DEM.The methodology was applied to an area in California, USA, including relatively flat terrain belonging to the Mohave desert as well as hilly to mountainous terrain of the San Gabriel and Tehachapi Mountains.
SAR11 Bacteria: The Most Abundant Plankton in the Oceans.
Giovannoni, Stephen J
2017-01-03
SAR11 is a group of small, carbon-oxidizing bacteria that reach a global estimated population size of 2.4×10 28 cells-approximately 25% of all plankton. They are found throughout the oceans but reach their largest numbers in stratified, oligotrophic gyres, which are an expanding habitat in the warming oceans. SAR11 likely had a Precambrian origin and, over geological time, evolved into the niche of harvesting labile, low-molecular-weight dissolved organic matter (DOM). SAR11 cells are minimal in size and complexity, a phenomenon known as streamlining that is thought to benefit them by lowering the material costs of replication and maximizing transport functions that are essential to competition at ultralow nutrient concentrations. One of the surprises in SAR11 metabolism is their ability to both oxidize and produce a variety of volatile organic compounds that can diffuse into the atmosphere. SAR11 cells divide slowly and lack many forms of regulation commonly used by bacterial cells to adjust to changing environmental conditions. As a result of genome reduction, they require an unusual range of nutrients, which leads to complex biochemical interactions with other plankton. The study of SAR11 is providing insight into the biogeochemistry of labile DOM and is affecting microbiology beyond marine science by providing a model for understanding the evolution and function of streamlined cells.
Solé, D; Ivancevich, J C; Borges, M S; Coelho, M A; Rosário, N A; Ardusso, L; Bernd, L A G
2012-01-01
To identify the main clinical manifestations, triggers, and treatment of severe allergic reactions (SAR) in children and adolescents (n=191, up to 18 years of age) seen by allergologists and registered in the Online Latin American Survey of Anaphylaxis (OLASA). 53.0% of the patients were males and the aetiological agent was identified in 85.5% of them as follows: foods (36.1%), drugs (27.7%), and insect stings (26.2%). The most common symptoms during an acute episode were cutaneous (94.2%), and respiratory (78.5%). Most patients were treated in emergency setting, yet only 34.6% received parenteral epinephrine and 14.3% had to be hospitalised. Cutaneous symptoms ranked the order of clinical presentation of SAR. Food was the main triggering agent in the younger cases and insect sting and drugs in the adolescents. Treatment provided for SAR was not appropriate. It is necessary to improve educational programmes in order to enhance the knowledge on this potentially fatal emergency. Copyright © 2011 SEICAP. Published by Elsevier Espana. All rights reserved.
Song, Haryong; Park, Yunjong; Kim, Hyungseup; Cho, Dong-Il Dan; Ko, Hyoungho
2015-10-14
Capacitive sensing schemes are widely used for various microsensors; however, such microsensors suffer from severe parasitic capacitance problems. This paper presents a fully integrated low-noise readout circuit with automatic offset cancellation loop (AOCL) for capacitive microsensors. The output offsets of the capacitive sensing chain due to the parasitic capacitances and process variations are automatically removed using AOCL. The AOCL generates electrically equivalent offset capacitance and enables charge-domain fine calibration using a 10-bit R-2R digital-to-analog converter, charge-transfer switches, and a charge-storing capacitor. The AOCL cancels the unwanted offset by binary-search algorithm based on 10-bit successive approximation register (SAR) logic. The chip is implemented using 0.18 μm complementary metal-oxide-semiconductor (CMOS) process with an active area of 1.76 mm². The power consumption is 220 μW with 3.3 V supply. The input parasitic capacitances within the range of -250 fF to 250 fF can be cancelled out automatically, and the required calibration time is lower than 10 ms.
Song, Haryong; Park, Yunjong; Kim, Hyungseup; Cho, Dong-il Dan; Ko, Hyoungho
2015-01-01
Capacitive sensing schemes are widely used for various microsensors; however, such microsensors suffer from severe parasitic capacitance problems. This paper presents a fully integrated low-noise readout circuit with automatic offset cancellation loop (AOCL) for capacitive microsensors. The output offsets of the capacitive sensing chain due to the parasitic capacitances and process variations are automatically removed using AOCL. The AOCL generates electrically equivalent offset capacitance and enables charge-domain fine calibration using a 10-bit R-2R digital-to-analog converter, charge-transfer switches, and a charge-storing capacitor. The AOCL cancels the unwanted offset by binary-search algorithm based on 10-bit successive approximation register (SAR) logic. The chip is implemented using 0.18 μm complementary metal-oxide-semiconductor (CMOS) process with an active area of 1.76 mm2. The power consumption is 220 μW with 3.3 V supply. The input parasitic capacitances within the range of −250 fF to 250 fF can be cancelled out automatically, and the required calibration time is lower than 10 ms. PMID:26473877
Comparison of four moderate-size earthquakes in southern California using seismology and InSAR
Mellors, R.J.; Magistrale, H.; Earle, P.; Cogbill, A.H.
2004-01-01
Source parameters determined from interferometric synthetic aperture radar (InSAR) measurements and from seismic data are compared from four moderate-size (less than M 6) earthquakes in southern California. The goal is to verify approximate detection capabilities of InSAR, assess differences in the results, and test how the two results can be reconciled. First, we calculated the expected surface deformation from all earthquakes greater than magnitude 4 in areas with available InSAR data (347 events). A search for deformation from the events in the interferograms yielded four possible events with magnitudes less than 6. The search for deformation was based on a visual inspection as well as cross-correlation in two dimensions between the measured signal and the expected signal. A grid-search algorithm was then used to estimate focal mechanism and depth from the InSAR data. The results were compared with locations and focal mechanisms from published catalogs. An independent relocation using seismic data was also performed. The seismic locations fell within the area of the expected rupture zone for the three events that show clear surface deformation. Therefore, the technique shows the capability to resolve locations with high accuracy and is applicable worldwide. The depths determined by InSAR agree with well-constrained seismic locations determined in a 3D velocity model. Depth control for well-imaged shallow events using InSAR data is good, and better than the seismic constraints in some cases. A major difficulty for InSAR analysis is the poor temporal coverage of InSAR data, which may make it impossible to distinguish deformation due to different earthquakes at the same location.
Yu, Dong; Zhang, Ruoyu; Liu, Qian
2012-09-01
To investigate the influence of dentures on electromagnetic energy absorption during the daily use of a mobile phone, a high-resolution head phantom based on the Visible Chinese Human dataset was reconstructed. Simulations on phantoms with various dentures were performed by using the finite-difference time-domain method with a 0.47 wavelength dipole antenna and a mobile phone model as radiation sources at 900 and 1800 MHz. The Specific energy Absorption Rate (SAR) values including 1 and 10 g average SAR values were assessed. When the metallic dental crowns with resonance lengths of approximately one-third to one-half wavelength in the tissue nearby are parallel to the radiation source, up to 121.6% relative enhancement for 1 g average SAR and 17.1% relative enhancement for 10 g average SAR are observed due to the resonance effect in energy absorption. When the radiation sources operate in the normal configuration, the 10 g average SAR values are still in compliance with the basic restrictions established by the Institute of Electrical and Electronic Engineers (IEEE) and the International Commission on Non-Ionizing Radiation Protection (ICNIRP), indicating that the safety limits will not be challenged by the usage of dentures. Copyright © 2012 Wiley Periodicals, Inc.
Monitoring of landslide deformation based on the coherent targets of high resolution InSAR data
NASA Astrophysics Data System (ADS)
Fan, Jinghui; Xia, Ye; Zhao, Hongli; Li, Man; Wang, Yi; Guo, Xiaofang; Tu, Pengfei; Liu, Guang; Lin, Hao
2014-05-01
Landslides are a kind of typical natural disaster in China, which pose serious threats to civil lives, property and living environment. Therefore, the identification, monitoring and prevention of landslides have been considered as a long-term geological work for the public welfare. In this article, 8 TerraSAR-X high resolution strip-map mode images, acquired in the period from January to March 2012 and covering Fanjinping landslide in Zigui county, Hubei province, were used to test the usability in monitoring the deformation of single landslide. The results of two-pass DInSAR sketched the region and the shape of the deformation field of Fanjiaping landslide. Corner reflectors' linear deformation rate using CRInSAR method could be approximately validated by the in-situ GPS measurements. From the coherent pixels' linear deformation rate map, it was inferred that the deformation could be more obvious in the tail of the Muyubao landslide while the lowest frontier of this landslide might prevent the slide. Due to its shorter revisiting period and high bandwidth,,the high resolution TerraSAR-X images can keep better coherence than previous satellite SAR data in the test area and provide basic guarantee to monitor the deformation of single landslides.
Extreme Magnetosphere-Ionosphere Coupling at the Plasmapause: a - In-A Bright SAR Arc
NASA Astrophysics Data System (ADS)
Baumgardner, J.; Wroten, J.; Semeter, J.; Mendillo, M.; Kozyra, J.
2007-05-01
Heat conduction from the ring current - plasmapause interaction region generates high electron temperature within the ionosphere that drive stable auroral red (SAR) arc emission at 6300 A. On the night of 29 October 1991, a SAR arc was observed using an all-sky imager and meridional imaging spectrograph at Millstone Hill. At xxxx UT, the SAR arc was south of Millstone at approximate L = 2 and reached emission levels of 13,000 rayleighs (R). Over two solar cycle of imaging observations have been made at Millstone Hill, and SAR arc brightness levels (excluding this event) averaged ~ 500 R. Simultaneous observations using the incoherent scatter radar (ISR), a DMSP satellite pass, the MSIS neutral atmosphere and SAR arc modeling using the Rees and Roble formalism succeeded in simulations of the observed emission. The reason for the unusual brightness was not the extreme temperatures achieved (and therefore heat conduction input), but the fact that the end of the plasmapause field line where the elevated Te values were measured did not occur in the ionospheric trough, but equatorward of it, thereby having far more ambient electrons to heat and subsequently collide with atomic oxygen. This unusual spatial geometry probably resulted from unusual convection patterns early in a superstorm scenario.
NASA Astrophysics Data System (ADS)
Sheveleva, Natalya G.; Itigilova, Mydygma Ts.; Chananbaator, Ayushcuren
2017-03-01
Data on zooplankton from 13 high-mountain lakes of East Siberia have shown that the Holarctic copepod Cyclops scutifer Sars, 1863 dominates among crustaceans. In July, its abundance comprised 64%-98% of the total plankton fauna in the pelagial of these lakes, approximately 30% in the littoral zone and 10% in small northern thermokarst lakes. Biometric measurements and morphological descriptions based on scanning microscope images are supplemented by the data on its geographic distribution and phenology.
Polishchuk, A V; Vodka, M V; Belyavskaya, N A; Khomochkin, A P; Zolotareva, E K
2016-01-01
The effects of simulated acid rain (SAR) on the ultrastructure and functional parameters of the photosynthetic apparatus were studied using 14-day-old pea leaves as test system. Pea plants were sprayed with an aqueous solution containing NaNO₃(0.2 mM) and Na₂SO₄(0.2 mM) (pH 5.6, a control variant), or with the same solution, which was acidified to pH 2.5 (acid variant). Functional characteristics were determined by chlorophyll fluorescence analysis. Acid rain application caused reduction in the efficiency of the photosynthetic electron transport by 25%, which was accompanied by an increase by 85% in the quantum yield of thermal dissipation of excess light quanta. Ultrastructural changes in chloroplast were registered by transmission electron microscopy (TEM) after two days of the SAR-treatment of pea leaves. In this case, the changes in the structure of grana, heterogeneity of thylakoids packaging in granum, namely, the increase of intra-thylakoid gaps and thickness of granal thylakoids compared to the control were found. The migration of protein complexes in thylakoid membranes of chloroplasts isolated from leaves treated with SAR was suppressed. It was shown also that carbonic anhydrase activity was inhibited in chloroplast preparations isolated from SAR-treated pea leaves. We proposed a hypothesis on the possible inactivation of thylakoid carbonic anhydrase under SAR and its involvement in the inhibition of photochemical activity of chloroplasts. The data obtained allows to suggest that acid rains negatively affect the photosynthetic apparatus disrupting the membrane system of chloroplast.
Airborne Multi-Band SAR in the Arctic
NASA Astrophysics Data System (ADS)
Gardner, J. M.; Brozena, J. M.; Liang, R.; Ball, D.; Holt, B.; Thomson, J.
2016-12-01
As one component of the Office of Naval Research supported Sea State Departmental Research Initiative during October of 2015 the Naval Research Laboratory flew an ultrawide-band, low-frequency, polarimetric SAR over the southward advancing sea ice in Beaufort Sea. The flights were coordinated with the research team aboard the R/V Sikuliaq working near and in the advancing pack ice. The majority of the SAR data were collected with the L-Band sensor (1000-1500 MHz) from an altitude of 10,000', providing a useful swath 6 km wide with 75o and 25 o angles of incidence at the inner and outer edge of the swath respectively. Some data were also collected with the P-Band SAR (215-915 MHz). The extremely large bandwidths allowed for formation of image pixels as small as 30 cm, however, we selected 60 cm pixel size to reduce image speckle. The separate polarimetric images are calibrated to one pixel to allow for calculations such as polarimetric decompositions that require the images to be well aligned. Both frequencies are useful particularly for the detection of ridges and areas of deformed ice. There are advantages and disadvantages to airborne SAR imagery compared to satellites. The chief advantages being the enormous allowable bandwidth leading to very fine range resolution, and the ability to fly arbitrary trajectories on demand. The latter permits specific areas to be imaged at a given time with a specified illumination direction. An area can even be illuminated from all directions by flying a circular trajectory around the target area. This captures ice features that are sensitive to illumination direction such as cracks, sastrugi orientation, and ridges. The disadvantages include variation of intensity across the swath with range and incidence angle. In addition to the SAR data, we collected photogrammetric imagery from a DSS-439, scanning lidar from a Riegl Q560 and surface brightness temperatures from a KT-19. However, since all of these sensors are nadir pointing, and some restricted to relatively low-altitude, it was difficult to obtain data co-registered with the SAR. At this meeting we will present some initial results from the SAR imagery, including differentiation of young, thin, and older ice features, and comparisons with satellite SAR with L-band and C-band frequencies.
Retrospective analysis of RF heating measurements of passive medical implants.
Song, Ting; Xu, Zhiheng; Iacono, Maria Ida; Angelone, Leonardo M; Rajan, Sunder
2018-05-09
The test reports for the RF-induced heating of metallic devices of hundreds of medical implants have been provided to the U.S. Food and Drug Administration as a part of premarket submissions. The main purpose of this study is to perform a retrospective analysis of the RF-induced heating data provided in the reports to analyze the trends and correlate them with implant geometric characteristics. The ASTM-based RF heating test reports from 86 premarket U.S. Food and Drug Administration submissions were reviewed by three U.S. Food and Drug Administration reviewers. From each test report, the dimensions and RF-induced heating values for a given whole-body (WB) specific absorption rate (SAR) and local background (LB) SAR were extracted and analyzed. The data from 56 stents were analyzed as a subset to further understand heating trends and length dependence. For a given WB SAR, the LB/WB SAR ratio varied significantly across the test labs, from 2.3 to 11.3. There was an increasing trend on the temperature change per LB SAR with device length. The maximum heating for stents occurred at lengths of approximately 100 mm at 3 T, and beyond 150 mm at 1.5 T. Differences in the LB/WB SAR ratios across testing labs and various MRI scanners could lead to inconsistent WB SAR labeling. Magnetic resonance (MR) conditional labeling based on WB SAR should be derived from a conservative estimate of global LB/WB ratios. Published 2018. This article is a U.S. Government work and is in the public domain in the USA.
Investigation of Land Subsidence using ALOS PALSAR data: a case study in Mentougou (Beijing, China)
NASA Astrophysics Data System (ADS)
Chen, Jianping; Xiang, Jie; Xie, Shuai; Liu, Jing; Tarolli, Paolo
2017-04-01
Mining activities have been documented for centuries in Mentougou, and land subsidence resulting from mining operations has already been known over the past few decades. However, there has been ongoing concern that excessive groundwater extraction may lead to further subsidence. Therefore it is critical to map the land cover changes to understand the actual impact of these activities. So, the land cover changes from 2006 to 2011 were examined based on multi-source remote sensing imageries( including ALOS and landsat-7) by using object-oriented classifications combined with a decision tree and retrospective approaches. Also, land subsidence in Mentougou between 2006 and 2011 has been mapped using the interferometric synthetic aperture radar (InSAR) time-series analysis with the ALOS L-band SAR data. We processed 14 ascending SAR images during May 2006 to July 2011. Comparison of InSAR measurements with the land cover changes and pre-existing faults suggest that mining activities is the main cause of land subsidence. The land subsidence observed from InSAR data are approximately up to 15 mm/year in open-pit mining area and up to 24 mm/year in underground mining areas. The InSAR result are validated by the ground survey data in several areas, and the comparison between the InSAR result with the mining schedule showed there were some correlations between them. The result underline the potential use of InSAR measurements to provide better investigation for land subsidence, and also suggest that the most influential factors for land subsidence is underground coal mine.
Source-Type Inversion of the September 03, 2017 DPRK Nuclear Test
NASA Astrophysics Data System (ADS)
Dreger, D. S.; Ichinose, G.; Wang, T.
2017-12-01
On September 3, 2017, the DPRK announced a nuclear test at their Punggye-ri site. This explosion registered a mb 6.3, and was well recorded by global and regional seismic networks. We apply the source-type inversion method (e.g. Ford et al., 2012; Nayak and Dreger, 2015), and the MDJ2 seismic velocity model (Ford et al., 2009) to invert low frequency (0.02 to 0.05 Hz) complete three-component waveforms, and first-motion polarities to map the goodness of fit in source-type space. We have used waveform data from the New China Digital Seismic Network (BJT, HIA, MDJ), Korean Seismic Network (TJN), and the Global Seismograph Network (INCN, MAJO). From this analysis, the event discriminates as an explosion. For a pure explosion model, we find a scalar seismic moment of 5.77e+16 Nm (Mw 5.1), however this model fails to fit the large Love waves registered on the transverse components. The best fitting complete solution finds a total moment of 8.90e+16 Nm (Mw 5.2) that is decomposed as 53% isotropic, 40% double-couple, and 7% CLVD, although the range of isotropic moment from the source-type analysis indicates that it could be as high as 60-80%. The isotropic moment in the source-type inversion is 4.75e16 Nm (Mw 5.05). Assuming elastic moduli from model MDJ2 the explosion cavity radius is approximately 51m, and the yield estimated using Denny and Johnson (1991) is 246kt. Approximately 8.5 minutes after the blast a second seismic event was registered, which is best characterized as a vertically closing horizontal crack, perhaps representing the partial collapse of the blast cavity, and/or a service tunnel. The total moment of the collapse is 3.34e+16 Nm (Mw 4.95). The volumetric moment of the collapse is 1.91e+16 Nm, approximately 1/3 to 1/2 of the explosive moment. German TerraSAR-X observations of deformation (Wang et al., 2017) reveal large radial outward motions consistent with expected deformation for an explosive source, but lack significant vertical motions above the shot point. Forward elastic half-space modeling of the static deformation field indicates that the combination of the explosion and collapse explains the observed deformation to first order. We will present these results as well as a two-step inversion of the explosion in an attempt to better resolve the nature of the non-isotropic radiation of the event.
Paulides, Margarethus M; Bakker, Jurriaan F; van Rhoon, Gerard C
2007-06-01
To experimentally verify the feasibility of focused heating in the neck region by an array of two rings of six electromagnetic antennas. We also measured the dynamic specific absorption rate (SAR) steering possibilities of this setup and compared these SAR patterns to simulations. Using a specially constructed laboratory prototype head-and-neck applicator, including a neck-mimicking cylindrical muscle phantom, we performed SAR measurements by electric field, Schottky-diode sheet measurements and, using the power-pulse technique, by fiberoptic thermometry and infrared thermography. Using phase steering, we also steered the SAR distribution in radial and axial directions. All measured distributions were compared with the predictions by a finite-difference time-domain-based electromagnetic simulator. A central 50% iso-SAR focus of 35 +/- 3 mm in diameter and about 100 +/- 15 mm in length was obtained for all investigated settings. Furthermore, this SAR focus could be steered toward the desired location in the radial and axial directions with an accuracy of approximately 5 mm. The SAR distributions as measured by all three experimental methods were well predicted by the simulations. The results of our study have shown that focused heating in the neck is feasible and that this focus can be effectively steered in the radial and axial directions. For quality assurance measurements, we believe that the Schottky-diode sheet provides the best compromise among effort, speed, and accuracy, although a more specific and improved design is warranted.
Clinical Description of a Completed Outbreak of SARS in Vietnam, February–May, 2003
Vu, Hoang Thu; Leitmeyer, Katrin C.; Le, Dang Ha; Miller, Megge J.; Nguyen, Quang Hien; Uyeki, Timothy M.; Reynolds, Mary G.; Aagesen, Jesper; Nicholson, Karl G.; Vu, Quang Huy; Bach, Huy Anh
2004-01-01
We investigated the clinical manifestations and course of all probable severe acute respiratory syndrome (SARS) patients in the Vietnam outbreak. Probable SARS cases were defined by using the revised World Health Organization criteria. We systematically reviewed medical records and undertook descriptive statistical analyses. All 62 patients were hospitalized. On admission, the most prominent symptoms were malaise (82.3%) and fever (79.0%). Cough, chest pain, and shortness of breath were present in approximately one quarter of the patients; 79.0% had lymphopenia; 40.3% had thrombocytopenia; 19.4% had leukopenia; and 75.8% showed changes on chest radiograph. Fever developed on the first day of illness onset, and both respiratory symptoms and radiographic changes occurred on day 4. On average, maximal radiographic changes were observed on day 10, and fevers subsided by day 13. Symptoms on admission were nonspecific, although fever, malaise, and lymphopenia were common. The complications of SARS included invasive intubation and ventilation (11.3%) and death (9.7%). PMID:15030707
Liu, Xilin; Zhang, Milin; Richardson, Andrew G; Lucas, Timothy H; Van der Spiegel, Jan
2017-08-01
This paper presents a bidirectional brain machine interface (BMI) microsystem designed for closed-loop neuroscience research, especially experiments in freely behaving animals. The system-on-chip (SoC) consists of 16-channel neural recording front-ends, neural feature extraction units, 16-channel programmable neural stimulator back-ends, in-channel programmable closed-loop controllers, global analog-digital converters (ADC), and peripheral circuits. The proposed neural feature extraction units includes 1) an ultra low-power neural energy extraction unit enabling a 64-step natural logarithmic domain frequency tuning, and 2) a current-mode action potential (AP) detection unit with time-amplitude window discriminator. A programmable proportional-integral-derivative (PID) controller has been integrated in each channel enabling a various of closed-loop operations. The implemented ADCs include a 10-bit voltage-mode successive approximation register (SAR) ADC for the digitization of the neural feature outputs and/or local field potential (LFP) outputs, and an 8-bit current-mode SAR ADC for the digitization of the action potential outputs. The multi-mode stimulator can be programmed to perform monopolar or bipolar, symmetrical or asymmetrical charge balanced stimulation with a maximum current of 4 mA in an arbitrary channel configuration. The chip has been fabricated in 0.18 μ m CMOS technology, occupying a silicon area of 3.7 mm 2 . The chip dissipates 56 μW/ch on average. General purpose low-power microcontroller with Bluetooth module are integrated in the system to provide wireless link and SoC configuration. Methods, circuit techniques and system topology proposed in this work can be used in a wide range of relevant neurophysiology research, especially closed-loop BMI experiments.
Vegetation canopy discrimination and biomass assessment using multipolarized airborne SAR
NASA Technical Reports Server (NTRS)
Ulaby, F. T.; Dobson, M. C.; Held, D. N.
1985-01-01
Multipolarized airborne Synthetic Aperture Radar (SAR) data were acquired over a largely agricultural test site near Macomb, Illinois, in conjunction with the Shuttle Imaging Radar (SIR-B) experiment in October 1984. The NASA/JPL L-band SAR operating at 1.225 GHz made a series of daily overflights with azimuth view angles both parallel and orthogonal to those of SIR-B. The SAR data was digitally recorded in the quadpolarization configuration. An extensive set of ground measurements were obtained throughout the test site and include biophysical and soil measurements of approximately 400 agricultural fields. Preliminary evaluation of some of the airborne SAR imagery indicates a great potential for crop discrimination and assessment of canopy condition. False color composites constructed from the combination of three linear polarizations (HH, VV, and HV) were found to be clearly superior to any single polarization for purposes of crop classification. In addition, an image constructed using the HH return to modulate intensity and the phase difference between HH and VV returns to modulate chroma indicates a clear capability for assessment of canopy height and/or biomass. In particular, corn fields heavily damaged by infestations of corn borer are readily distinguished from noninfested fields.
Maintenance of biodiversity on islands.
Chisholm, Ryan A; Fung, Tak; Chimalakonda, Deepthi; O'Dwyer, James P
2016-04-27
MacArthur and Wilson's theory of island biogeography predicts that island species richness should increase with island area. This prediction generally holds among large islands, but among small islands species richness often varies independently of island area, producing the so-called 'small-island effect' and an overall biphasic species-area relationship (SAR). Here, we develop a unified theory that explains the biphasic island SAR. Our theory's key postulate is that as island area increases, the total number of immigrants increases faster than niche diversity. A parsimonious mechanistic model approximating these processes reproduces a biphasic SAR and provides excellent fits to 100 archipelago datasets. In the light of our theory, the biphasic island SAR can be interpreted as arising from a transition from a niche-structured regime on small islands to a colonization-extinction balance regime on large islands. The first regime is characteristic of classic deterministic niche theories; the second regime is characteristic of stochastic theories including the theory of island biogeography and neutral theory. The data furthermore confirm our theory's key prediction that the transition between the two SAR regimes should occur at smaller areas, where immigration is stronger (i.e. for taxa that are better dispersers and for archipelagos that are less isolated). © 2016 The Author(s).
NASA Astrophysics Data System (ADS)
Yang, Jiaqi; Li, Ting; Yu, Mingyuan; Zhang, Shuangshuang; Lin, Fujiang; He, Lin
2017-08-01
This paper analyzes the power consumption and delay mechanisms of the successive-approximation (SA) logic of a typical asynchronous SAR ADC, and provides strategies to reduce both of them. Following these strategies, a unique direct-pass SA logic is proposed based on a full-swing once-triggered DFF and a self-locking tri-state gate. The unnecessary internal switching power of a typical TSPC DFF, which is commonly used in the SA logic, is avoided. The delay of the ready detector as well as the sequencer is removed from the critical path. A prototype SAR ADC based on the proposed SA logic is fabricated in 130 nm CMOS. It achieves a peak SNDR of 56.3 dB at 1.2 V supply and 65 MS/s sampling rate, and has a total power consumption of 555 μW, while the digital part consumes only 203 μW. Project supported by the National Natural Science Foundation of China (Nos. 61204033, 61331015), the Fundamental Research Funds for the Central Universities (No. WK2100230015), and the Funds of Science and Technology on Analog Integrated Circuit Laboratory (No. 9140C090111150C09041).
NASA Astrophysics Data System (ADS)
Ji, Lingyun; Wang, Qingliang; Xu, Jing; Ji, Cunwei
2017-03-01
On July 11, 1995, an Mw 6.8 earthquake struck eastern Myanmar near the Chinese border; hereafter referred to as the 1995 Myanmar-China earthquake. Coseismic surface displacements associated with this event are identified from JERS-1 (Japanese Earth Resources Satellite-1) SAR (Synthetic Aperture Radar) images. The largest relative displacement reached 60 cm in the line-of-sight direction. We speculate that a previously unrecognized dextral strike-slip subvertical fault striking NW-SE was responsible for this event. The coseismic slip distribution on the fault planes is inverted based on the InSAR-derived deformation. The results indicate that the fault slip was confined to two lobes. The maximum slip reached approximately 2.5 m at a depth of 5 km in the northwestern part of the focal region. The inverted geodetic moment was approximately Mw = 6.69, which is consistent with seismological results. The 1995 Myanmar-China earthquake is one of the largest recorded earthquakes that has occurred around the "bookshelf faulting" system between the Sagaing fault in Myanmar and the Red River fault in southwestern China.
Vaisson, Gratianne; Witteman, Holly O; Bouck, Zachary; Bravo, Caroline A; Desveaux, Laura; Llovet, Diego; Presseau, Justin; Saragosa, Marianne; Taljaard, Monica; Umar, Shama; Grimshaw, Jeremy M; Tinmouth, Jill; Ivers, Noah M
2018-02-16
Cancer Care Ontario's Screening Activity Report (SAR) is an online audit and feedback tool designed to help primary care physicians in Ontario, Canada, identify patients who are overdue for cancer screening or have abnormal results requiring follow-up. Use of the SAR is associated with increased screening rates. To encourage SAR use, Cancer Care Ontario sends monthly emails to registered primary care physicians announcing that updated data are available. However, analytics reveal that 50% of email recipients do not open the email and less than 7% click the embedded link to log in to their report. The goal of the study is to determine whether rewritten emails result in increased log-ins. This manuscript describes how different user- and theory-informed messages intended to improve the impact of the monthly emails will be experimentally tested and how a process evaluation will explore why and how any effects observed were (or were not) achieved. A user-centered approach was used to rewrite the content of the monthly email, including messages operationalizing 3 behavior change techniques: anticipated regret, material incentive (behavior), and problem solving. A pragmatic, 2x2x2 factorial experiment within a multiphase optimization strategy will test the redesigned emails with an embedded qualitative process evaluation to understand how and why the emails may or may not have worked. Trial outcomes will be ascertained using routinely collected administrative data. Physicians will be recruited for semistructured interviews using convenience and snowball sampling. As of April 2017, 5576 primary care physicians across the province of Ontario, Canada, had voluntarily registered for the SAR, and in so doing, signed up to receive the monthly email updates. From May to August 2017 participants received the redesigned monthly emails with content specific to their allocated experimental condition prompting use of the SAR. We have not yet begun analyses. This study will inform how to communicate effectively with primary care providers by email and identify which behavior change techniques tested are most effective at encouraging engagement with an audit and feedback report. ClinicalTrials.gov NCT03124316; https://clinicaltrials.gov/ct2/show/NCT03124316 (Archived by WebCite at http://www.webcitation.org/6w2MqDWGu). ©Gratianne Vaisson, Holly O Witteman, Zachary Bouck, Caroline A Bravo, Laura Desveaux, Diego Llovet, Justin Presseau, Marianne Saragosa, Monica Taljaard, Shama Umar, Jeremy M Grimshaw, Jill Tinmouth, Noah M Ivers. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 16.02.2018.
The Born approximation, multiple scattering, and the butterfly algorithm
NASA Astrophysics Data System (ADS)
Martinez, Alejandro F.
Radar works by focusing a beam of light and seeing how long it takes to reflect. To see a large region the beam is pointed in different directions. The focus of the beam depends on the size of the antenna (called an aperture). Synthetic aperture radar (SAR) works by moving the antenna through some region of space. A fundamental assumption in SAR is that waves only bounce once. Several imaging algorithms have been designed using that assumption. The scattering process can be described by iterations of a badly behaving integral. Recently a method for efficiently evaluating these types of integrals has been developed. We will give a detailed implementation of this algorithm and apply it to study the multiple scattering effects in SAR using target estimates from single scattering algorithms.
NASA Astrophysics Data System (ADS)
Sterzai, P.; Mancini, F.; Corazzato, C.; D Agata, C.; Diolaiuti, G.
2003-04-01
Aiming at reconstructing superficial velocity and volumetric variations of alpine glaciers, SAR interferometry (InSAR) technique is, for the first time in Italy, applied jointly with the glaciological classic field methods. This methodology with its quantitative results provides, together with other space geodesy techniques like GPS, some fundamental elements for the estimation of the climate forcing and the evaluation of the future glacier trend. InSAR is usually applied to antarctic glaciers and to other wide extralpine glaciers, detectable by the SAR orbits; in the Italian Alps, the limited surface area of the glaciers and the deformation of radar images due to strong relief effect, reduce the applicability of this tecnique. The chosen glacier is suitable for this kind of study both for its large size and for the many field data collected and available for the interferometric results validation. Forni Glacier is the largest valley glacier in the Italian Alps and represents a good example of long term monitoring of a valley glacier in the Central Alps. It is a north facing valley glacier formed by 3 ice streams, located in Italian Lombardy Alps (46 23 50 N, 10 35 00 E). In 2002 its area was approximately 13 km2, extending from 2500 to 3684 m a.s.l., with a maximum width of approximately 7500 m and a maximum length of about 5000 m. Available data include mass-balance measurements on the glacier tongue (from the hydrological year 1992-1993 up to now), frontal variations data from 1925 up to now, topographical profiling by means of GPS techniques and profiles of the glacier bed by geoelectrical surveys (VES) (Guglielmin et alii, 1995) and by seismic surveys (Merlanti et alii, 2001). In order to apply radar interferometry on this glacier eight ERS SAR RAW images have been purchased, in addition to the Digital Elevation Model from IGM (Geographic Military Institute), and repeat pass interferometry used. Combining the different passes, differential interferograms are computed and velocity map obtained. The validation of interferometric data was possible comparing them with the field glaciological data obtained by GPS velocity surveys in the years 1992-1993 (Vittuari and Smiraglia, unpublished) and 1996-1997, which resulted of about 20m/y. The InSAR results give further contributions in the estimation of the velocity field of Forni Glacier for a deeper understanding of the different flow lines of the glacier. Problems related to relief effect, loss of coherence, geometry of satellite imagery and geocoding, are also discussed.
Impact of quarantine on the 2003 SARS outbreak: a retrospective modeling study.
Hsieh, Ying-Hen; King, Chwan-Chuan; Chen, Cathy W S; Ho, Mei-Shang; Hsu, Sze-Bi; Wu, Yi-Chun
2007-02-21
During the 2003 Severe Acute Respiratory Syndrome (SARS) outbreak, traditional intervention measures such as quarantine and border control were found to be useful in containing the outbreak. We used laboratory verified SARS case data and the detailed quarantine data in Taiwan, where over 150,000 people were quarantined during the 2003 outbreak, to formulate a mathematical model which incorporates Level A quarantine (of potentially exposed contacts of suspected SARS patients) and Level B quarantine (of travelers arriving at borders from SARS affected areas) implemented in Taiwan during the outbreak. We obtain the average case fatality ratio and the daily quarantine rate for the Taiwan outbreak. Model simulations is utilized to show that Level A quarantine prevented approximately 461 additional SARS cases and 62 additional deaths, while the effect of Level B quarantine was comparatively minor, yielding only around 5% reduction of cases and deaths. The combined impact of the two levels of quarantine had reduced the case number and deaths by almost a half. The results demonstrate how modeling can be useful in qualitative evaluation of the impact of traditional intervention measures for newly emerging infectious diseases outbreak when there is inadequate information on the characteristics and clinical features of the new disease-measures which could become particularly important with the looming threat of global flu pandemic possibly caused by a novel mutating flu strain, including that of avian variety.
Detecting and monitoring UCG subsidence with InSAR
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mellors, R J; Foxall, W; Yang, X
2012-03-23
The use of interferometric synthetic aperture radar (InSAR) to measure surface subsidence caused by Underground Coal Gasification (UCG) is tested. InSAR is a remote sensing technique that uses Synthetic Aperture Radar images to make spatial images of surface deformation and may be deployed from satellite or an airplane. With current commercial satellite data, the technique works best in areas with little vegetation or farming activity. UCG subsidence is generally caused by roof collapse, which adversely affects UCG operations due to gas loss and is therefore important to monitor. Previous studies have demonstrated the usefulness of InSAR in measuring surface subsidencemore » related to coal mining and surface deformation caused by a coal mining roof collapse in Crandall Canyon, Utah is imaged as a proof-of-concept. InSAR data is collected and processed over three known UCG operations including two pilot plants (Majuba, South Africa and Wulanchabu, China) and an operational plant (Angren, Uzbekistan). A clear f eature showing approximately 7 cm of subsidence is observed in the UCG field in Angren. Subsidence is not observed in the other two areas, which produce from deeper coal seams and processed a smaller volume. The results show that in some cases, InSAR is a useful tool to image UCG related subsidence. Data from newer satellites and improved algorithms will improve effectiveness.« less
NASA Astrophysics Data System (ADS)
Nikolov, Hristo; Atanasova, Mila
2017-10-01
One of the key input parameters in obtaining end products from SAR data is the DEM used during their processing. This holds true especially when persistent scatterers InSAR method should be applied for example to study slow moving landslides or subsidence. Since nowadays most of the raw SAR data are of space borne origin for their correct processing to high precision products for relatively small areas with centimeter accuracy a DEM taking into account the particularities of the local topography is needed. Most of the DEMs used by the SAR processing software such as SRTM or ASTER are obtained by the same type of instrument and present some disagreements with height information acquired by leveling measurements or other geodetic means. This was the motivation for initiating this research - to prove the need of creating and using local DEM in SAR data processing at small scale and to check what the magnitude of the discrepancy between final InSAR products is in both cases where SRTM/ASTER and local DEM has been used. In addition investigated were two scenarios for SAR data processing - one with small baseline between image pairs and one having large baseline image pairs - in order to find out in which case local DEM has bigger impact. In course of this study two reference areas were considered - Bankya village near Sofia (SW region of Bulgaria) and Mirovo salt extraction site (NE region of Bulgaria). The reason those areas were selected lies in the high number of landslides registered and monitored by the competent authorities in the mentioned locations. The significance of the results obtained is witnessed by the fact that both sites we used have been included as reference sites for Bulgaria in the PanGeo EU funded project dealing with delivering information regarding ground instability geohazard as areas prone to subsidence of natural and manmade origin. In the said project largest part of the information has been extracted from Envisat SAR data, but now this information could be supplemented by adding such from Sentinel-1 derived by us. During this research two local DEMs have been extracted from the tiles including the areas of investigation, one using SRTM data and one from ASTER, and after this procedure both were compared to the DEM gathered by leveling measurements. Finally conclusions are drawn and a direction for future research steps is provided.
a High Precision dem Extraction Method Based on Insar Data
NASA Astrophysics Data System (ADS)
Wang, Xinshuang; Liu, Lingling; Shi, Xiaoliang; Huang, Xitao; Geng, Wei
2018-04-01
In the 13th Five-Year Plan for Geoinformatics Business, it is proposed that the new InSAR technology should be applied to surveying and mapping production, which will become the innovation driving force of geoinformatics industry. This paper will study closely around the new outline of surveying and mapping and then achieve the TerraSAR/TanDEM data of Bin County in Shaanxi Province in X band. The studying steps are as follows; Firstly, the baseline is estimated from the orbital data; Secondly, the interferometric pairs of SAR image are accurately registered; Thirdly, the interferogram is generated; Fourth, the interferometric correlation information is estimated and the flat-earth phase is removed. In order to solve the phase noise and the discontinuity phase existing in the interferometric image of phase, a GAMMA adaptive filtering method is adopted. Aiming at the "hole" problem of missing data in low coherent area, the interpolation method of low coherent area mask is used to assist the phase unwrapping. Then, the accuracy of the interferometric baseline is estimated from the ground control points. Finally, 1 : 50000 DEM is generated, and the existing DEM data is used to verify the accuracy through statistical analysis. The research results show that the improved InSAR data processing method in this paper can obtain the high-precision DEM of the study area, exactly the same with the topography of reference DEM. The R2 can reach to 0.9648, showing a strong positive correlation.
Techniques and Tools for Estimating Ionospheric Effects in Interferometric and Polarimetric SAR Data
NASA Technical Reports Server (NTRS)
Rosen, P.; Lavalle, M.; Pi, X.; Buckley, S.; Szeliga, W.; Zebker, H.; Gurrola, E.
2011-01-01
The InSAR Scientific Computing Environment (ISCE) is a flexible, extensible software tool designed for the end-to-end processing and analysis of synthetic aperture radar data. ISCE inherits the core of the ROI_PAC interferometric tool, but contains improvements at all levels of the radar processing chain, including a modular and extensible architecture, new focusing approach, better geocoding of the data, handling of multi-polarization data, radiometric calibration, and estimation and correction of ionospheric effects. In this paper we describe the characteristics of ISCE with emphasis on the ionospheric modules. To detect ionospheric anomalies, ISCE implements the Faraday rotation method using quadpolarimetric images, and the split-spectrum technique using interferometric single-, dual- and quad-polarimetric images. The ability to generate co-registered time series of quad-polarimetric images makes ISCE also an ideal tool to be used for polarimetric-interferometric radar applications.
Properties of knotted ring polymers. I. Equilibrium dimensions.
Mansfield, Marc L; Douglas, Jack F
2010-07-28
We report calculations on three classes of knotted ring polymers: (1) simple-cubic lattice self-avoiding rings (SARs), (2) "true" theta-state rings, i.e., SARs generated on the simple-cubic lattice with an attractive nearest-neighbor contact potential (theta-SARs), and (3) ideal, Gaussian rings. Extrapolations to large polymerization index N imply knot localization in all three classes of chains. Extrapolations of our data are also consistent with conjectures found in the literature which state that (1) R(g)-->AN(nu) asymptotically for ensembles of random knots restricted to any particular knot state, including the unknot; (2) A is universal across knot types for any given class of flexible chains; and (3) nu is equal to the standard self-avoiding walk (SAW) exponent (congruent with 0.588) for all three classes of chains (SARs, theta-SARs, and ideal rings). However, current computer technology is inadequate to directly sample the asymptotic domain, so that we remain in a crossover scaling regime for all accessible values of N. We also observe that R(g) approximately p(-0.27), where p is the "rope length" of the maximally inflated knot. This scaling relation holds in the crossover regime, but we argue that it is unlikely to extend into the asymptotic scaling regime where knots become localized.
Tie Points Extraction for SAR Images Based on Differential Constraints
NASA Astrophysics Data System (ADS)
Xiong, X.; Jin, G.; Xu, Q.; Zhang, H.
2018-04-01
Automatically extracting tie points (TPs) on large-size synthetic aperture radar (SAR) images is still challenging because the efficiency and correct ratio of the image matching need to be improved. This paper proposes an automatic TPs extraction method based on differential constraints for large-size SAR images obtained from approximately parallel tracks, between which the relative geometric distortions are small in azimuth direction and large in range direction. Image pyramids are built firstly, and then corresponding layers of pyramids are matched from the top to the bottom. In the process, the similarity is measured by the normalized cross correlation (NCC) algorithm, which is calculated from a rectangular window with the long side parallel to the azimuth direction. False matches are removed by the differential constrained random sample consensus (DC-RANSAC) algorithm, which appends strong constraints in azimuth direction and weak constraints in range direction. Matching points in the lower pyramid images are predicted with the local bilinear transformation model in range direction. Experiments performed on ENVISAT ASAR and Chinese airborne SAR images validated the efficiency, correct ratio and accuracy of the proposed method.
A modified sparse reconstruction method for three-dimensional synthetic aperture radar image
NASA Astrophysics Data System (ADS)
Zhang, Ziqiang; Ji, Kefeng; Song, Haibo; Zou, Huanxin
2018-03-01
There is an increasing interest in three-dimensional Synthetic Aperture Radar (3-D SAR) imaging from observed sparse scattering data. However, the existing 3-D sparse imaging method requires large computing times and storage capacity. In this paper, we propose a modified method for the sparse 3-D SAR imaging. The method processes the collection of noisy SAR measurements, usually collected over nonlinear flight paths, and outputs 3-D SAR imagery. Firstly, the 3-D sparse reconstruction problem is transformed into a series of 2-D slices reconstruction problem by range compression. Then the slices are reconstructed by the modified SL0 (smoothed l0 norm) reconstruction algorithm. The improved algorithm uses hyperbolic tangent function instead of the Gaussian function to approximate the l0 norm and uses the Newton direction instead of the steepest descent direction, which can speed up the convergence rate of the SL0 algorithm. Finally, numerical simulation results are given to demonstrate the effectiveness of the proposed algorithm. It is shown that our method, compared with existing 3-D sparse imaging method, performs better in reconstruction quality and the reconstruction time.
Mount Etna InSAR Time Series Animation
2012-02-06
This animation depicts a time-series of ground deformation at Mount Etna Volcano between 1992 and 2001. The deformation results from changes in the volume of a shallow chamber centered approximately 5 km 3 miles below sea level.
Wainwright, P R
2003-10-07
Of the biological effects of human exposure to radiofrequency and microwave radiation, the best-established are those due to elevation of tissue temperature. To prevent harmful levels of heating, restrictions have been proposed on the specific absorption rate (SAR). However, the relationship between SAR and temperature rise is not an invariant, since not only the heat capacity but also the efficiency of heat dissipation varies between different tissues and exposure scenarios. For small enough SAR, the relationship is linear and may be characterized by a 'heating factor' deltaT/SAR. Under whole-body irradiation the SAR may be particularly high in the ankles due to the concentration of current flowing through a relatively small cross-sectional area. In a previous paper, the author has presented calculations of the SAR distribution in a human leg in the high frequency (HF) band. In this paper, the heating factor for this situation is derived using a finite element approximation of the Pennes bioheat equation. The sensitivity of the results to different blood perfusion rates is investigated, and a simple local thermoregulatory model is applied. Both time-dependent and steady-state solutions are considered. Results confirm the appropriateness of the ICNIRP reference level of 100 mA on current through the leg, but suggest that at higher currents significant thermoregulatory adjustments to muscle blood flow will occur.
Software for Generating Strip Maps from SAR Data
NASA Technical Reports Server (NTRS)
Hensley, Scott; Michel, Thierry; Madsen, Soren; Chapin, Elaine; Rodriguez, Ernesto
2004-01-01
Jurassicprok is a computer program that generates strip-map digital elevation models and other data products from raw data acquired by an airborne synthetic-aperture radar (SAR) system. This software can process data from a variety of airborne SAR systems but is designed especially for the GeoSAR system, which is a dual-frequency (P- and X-band), single-pass interferometric SAR system for measuring elevation both at the bare ground surface and top of the vegetation canopy. Jurassicprok is a modified version of software developed previously for airborne-interferometric- SAR applications. The modifications were made to accommodate P-band interferometric processing, remove approximations that are not generally valid, and reduce processor-induced mapping errors to the centimeter level. Major additions and other improvements over the prior software include the following: a) A new, highly efficient multi-stage-modified wave-domain processing algorithm for accurately motion compensating ultra-wideband data; b) Adaptive regridding algorithms based on estimated noise and actual measured topography to reduce noise while maintaining spatial resolution; c) Exact expressions for height determination from interferogram data; d) Fully calibrated volumetric correlation data based on rigorous removal of geometric and signal-to-noise decorrelation terms; e) Strip range-Doppler image output in user-specified Doppler coordinates; f) An improved phase-unwrapping and absolute-phase-determination algorithm; g) A more flexible user interface with many additional processing options; h) Increased interferogram filtering options; and i) Ability to use disk space instead of random- access memory for some processing steps.
Successive Over-Relaxation Technique for High-Performance Blind Image Deconvolution
2015-06-08
deconvolution, space surveillance, Gauss - Seidel iteration 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT SAR 18, NUMBER OF PAGES 5...sensible approximate solutions to the ill-posed nonlinear inverse problem. These solutions are addresses as fixed points of the iteration which consists in...alternating approximations (AA) for the object and for the PSF performed with a prescribed number of inner iterative descents from trivial (zero
Accurate numerical forward model for optimal retracking of SIRAL2 SAR echoes over open ocean
NASA Astrophysics Data System (ADS)
Phalippou, L.; Demeestere, F.
2011-12-01
The SAR mode of SIRAL-2 on board Cryosat-2 has been designed to measure primarily sea-ice and continental ice (Wingham et al. 2005). In 2005, K. Raney (KR, 2005) pointed out the improvements brought by SAR altimeter for open ocean. KR results were mostly based on 'rule of thumb' considerations on speckle noise reduction due to the higher PRF and to speckle decorrelation after SAR processing. In 2007, Phalippou and Enjolras (PE,2007) provided the theoretical background for optimal retracking of SAR echoes over ocean with a focus on the forward modelling of the power-waveforms. The accuracies of geophysical parameters (range, significant wave heights, and backscattering coefficient) retrieved from SAR altimeter data were derived accounting for SAR echo shape and speckle noise accurate modelling. The step forward to optimal retracking using numerical forward model (NFM) was also pointed out. NFM of the power waveform avoids analytical approximation, a warranty to minimise the geophysical dependent biases in the retrieval. NFM have been used for many years, in operational meteorology in particular, for retrieving temperature and humidity profiles from IR and microwave radiometers as the radiative transfer function is complex (Eyre, 1989). So far this technique was not used in the field of ocean conventional altimetry as analytical models (e.g. Brown's model for instance) were found to give sufficient accuracy. However, although NFM seems desirable even for conventional nadir altimetry, it becomes inevitable if one wish to process SAR altimeter data as the transfer function is too complex to be approximated by a simple analytical function. This was clearly demonstrated in PE 2007. The paper describes the background to SAR data retracking over open ocean. Since PE 2007 improvements have been brought to the forward model and it is shown that the altimeter on-ground and in flight characterisation (e.g antenna pattern range impulse response, azimuth impulse response, altimeter transfer function) can be accurately accounted for, in order to minimise the systematic errors in the retrieval. The paper presents the retrieval of range and SWH for several Cryosat 2 orbits arcs, spanning different sea state conditions. The retrieval results are found to be in excellent agreement with the noise expectations derived from the Cramer-Rao bounds (see PE 2007.). The improvement upon conventional Low Resolution mode is about a factor of two in range. Improvements in SWH accuracy is also discussed. Comparisons with the MSL and conventional LRM-like retracking is also shown. Finally, the paper will give some insights for future oceanic altimetry missions. References : Wingham et al., 2005 : CryoSat: A mission to determine the fluctuations in Earth's land and marine ice fields. Advances in Space Research 37 (2006) 841-871 Raney, R.K. 2005 : Resolution and precision ofa delayDoppler Radar Altimeter, Proc IEEE OCEANS 2005. Phalippou L, V. Enjolras 2007 : Re-tracking of SAR altimeter ocean power waveforms and related accuracies of Sea surface Height, significant wave height and wind speed. Proc IEEE IGARSS 2007. Eyre, J. 1989 : Inversion of cloudy satellite radiances by non linear estimation : Theory and simulation for TOVS. Quaterly Journal of the Royal Meteorological Society, 115, pp1001-1026.
SAR by Oxime-Containing Peptide Libraries: Application to Tsg101 Ligand Optimization
Liu, Fa; Stephen, Andrew G.; Waheed, Abdul A.; Aman, M. Javad; Freed, Eric O.; Fisher, Robert J.; Burke, Terrence R.
2008-01-01
HIV-1 viral assembly requires a direct interaction between a Pro-Thr-Ala-Pro (“PTAP”) motif in the viral protein Gag-p6 and the cellular endosomal sorting factor Tsg101. In an effort to develop competitive inhibitors of this interaction, an SAR study was conducted based on the application of post solid-phase oxime formation involving the sequential insertion of aminooxy-containing residues within a nonamer parent peptide followed by reaction with libraries of aldehydes. Approximately 15–20-fold enhancement in binding affinity was achieved by this approach. PMID:18655064
A Low Power Digital Accumulation Technique for Digital-Domain CMOS TDI Image Sensor.
Yu, Changwei; Nie, Kaiming; Xu, Jiangtao; Gao, Jing
2016-09-23
In this paper, an accumulation technique suitable for digital domain CMOS time delay integration (TDI) image sensors is proposed to reduce power consumption without degrading the rate of imaging. In terms of the slight variations of quantization codes among different pixel exposures towards the same object, the pixel array is divided into two groups: one is for coarse quantization of high bits only, and the other one is for fine quantization of low bits. Then, the complete quantization codes are composed of both results from the coarse-and-fine quantization. The equivalent operation comparably reduces the total required bit numbers of the quantization. In the 0.18 µm CMOS process, two versions of 16-stage digital domain CMOS TDI image sensor chains based on a 10-bit successive approximate register (SAR) analog-to-digital converter (ADC), with and without the proposed technique, are designed. The simulation results show that the average power consumption of slices of the two versions are 6 . 47 × 10 - 8 J/line and 7 . 4 × 10 - 8 J/line, respectively. Meanwhile, the linearity of the two versions are 99.74% and 99.99%, respectively.
Observation of melt onset on multiyear Arctic sea ice using the ERS 1 synthetic aperture radar
NASA Technical Reports Server (NTRS)
Winebrenner, D. P.; Nelson, E. D.; Colony, R.; West, R. D.
1994-01-01
We present nearly coincident observations of backscattering from the Earth Remote-Sensing Satellite (ERS) 1 synthetic aperture radar (SAR) and of near-surface temperature from six drifting buoys in the Beaufort Sea, showing that the onset of melting in snow on multiyear sea ice is clearly detectable in the SAR data. Melt onset is marked by a clean, steep decrease in the backscattering cross section of multiyear ice at 5.3 GHz and VV polarization. We investigate the scattering physics responsible for the signature change and find that the cross section decrease is due solely to the appearance of liquid water in the snow cover overlying the ice. A thin layer of moist snow is sufficient to cause the observed decrease. We present a prototype algorithm to estimate the date of melt onset using the ERS 1 SAR and apply the algorithm first to the SAR data for which we have corresponding buoy temperatures. The melt onset dates estimated by the SAR algorithm agree with those obtained independently from the temperature data to within 4 days or less, with the exception of one case in which temperatures oscillated about 0 C for several weeks. Lastly, we apply the algorithm to the entire ERS 1 SAR data record acquired by the Alaska SAR Facility for the Beaufort Sea north of 73 deg N during the spring of 1992, to produce a map of the dates of melt onset over an area roughly 1000 km on a side. The progression of melt onset is primarily poleward but shows a weak meridional dependence at latitudes of approximately 76 deg-77 deg N. Melting begins in the southern part of the study region on June 13 and by June 20 has progressed to the northermost part of the region.
Jappar, Dilara; Wu, Shu-Pei; Hu, Yongjun
2010-01-01
The purpose of this study was to evaluate the role, relevance, and regional dependence of peptide transporter (PEPT) 1 expression and function in mouse intestines using the model dipeptide glycylsarcosine (GlySar). After isolating specific intestinal segments, in situ single-pass perfusions were performed in wild-type and Pept1 knockout mice. The permeability of [3H]GlySar was measured as a function of perfusate pH, dipeptide concentration, potential inhibitors, and intestinal segment, along with PEPT1 mRNA and protein. We found the permeability of GlySar to be saturable (Km = 5.7 mM), pH-dependent (maximal value at pH 5.5), and specific for PEPT1; other peptide transporters, such as PHT1 and PHT2, were not involved, as judged by the lack of GlySar inhibition by excess concentrations of histidine. GlySar permeabilities were comparable in the duodenum and jejunum of wild-type mice but were much larger than that in ileum (approximately 2-fold). A PEPT1-mediated permeability was not observed for GlySar in the colon of wild-type mice (<10% residual uptake compared to proximal small intestine). Moreover, GlySar permeabilities were very low and not different in the duodenum, jejunum, ileum, and colon of Pept1 knockout mice. Functional activity of intestinal PEPT1 was confirmed by real-time polymerase chain reaction and immunoblot analyses. Our findings suggest that a loss of PEPT1 activity (e.g., due to polymorphisms, disease, or drug interactions) should have a major effect in reducing the intestinal absorption of di-/tripeptides, peptidomimetics, and peptide-like drugs. PMID:20660104
Detection and tracking of a low energy swell system off the U.S. East Coast with the Seasat SAR
NASA Technical Reports Server (NTRS)
Beal, R. C.
1980-01-01
It is noted that on the morning of September 28, 1978, at 1520 GMT, Seasat approached the East Coast of the U.S. with the 100 km swath of its synthetic aperture radar (SAR) running approximately parallel to the coast but displayed eastward by about 20 km. This pass is analyzed and the following conclusions are drawn: (1) the SAR can successfully detect low-energy swell systems with wave heights under 1 m (actually 0.65 + or - 0.25 m); (2) the refraction of low-energy but well-organized swells deriving from changes in the local depth of the ocean is clearly detectable in both wavelength and direction; and (3) the complexity of the ocean spectrum (whether composed of more than one system or spread in direction and wave number) appears to have little bearing on the threshold detection limits.
Accuracy improvement of the ice flow rate measurements on Antarctic ice sheet by DInSAR method
NASA Astrophysics Data System (ADS)
Shiramizu, Kaoru; Doi, Koichiro; Aoyama, Yuichi
2015-04-01
DInSAR (Differential Interferometric Synthetic Aperture Radar) is an effective tool to measure the flow rate of slow flowing ice streams on Antarctic ice sheet with high resolution. In the flow rate measurement by DInSAR method, we use Digital Elevation Model (DEM) at two times in the estimating process. At first, we use it to remove topographic fringes from InSAR images. And then, it is used to project obtained displacements along Line-Of-Sight (LOS) direction to the actual flow direction. ASTER-GDEM widely-used for InSAR prosessing of the data of polar region has a lot of errors especially in the inland ice sheet area. Thus the errors yield irregular flow rates and directions. Therefore, quality of DEM has a substantial influence on the ice flow rate measurement. In this study, we created a new DEM (resolution 10m; hereinafter referred to as PRISM-DEM) based on ALOS/PRISM images, and compared PRISM-DEM and ASTER-GDEM. The study area is around Skallen, 90km south from Syowa Station, in the southern part of Sôya Coast, East Antarctica. For making DInSAR images, we used ALOS/PALSAR data of 13 pairs (Path633, Row 571-572), observed during the period from November 23, 2007 through January 16, 2011. PRISM-DEM covering the PALSAR scene was created from nadir and backward view images of ALOS/PRISM (Observation date: 2009/1/18) by applying stereo processing with a digital mapping equipment, and then the automatically created a primary DEM was corrected manually to make a final DEM. The number of irregular values of actual ice flow rate was reduced by applying PRISM-DEM compared with that by applying ASTER-GDEM. Additionally, an averaged displacement of approximately 0.5cm was obtained by applying PRISM-DEM over outcrop area, where no crustal displacement considered to occur during the recurrence period of ALOS/PALSAR (46days), while an averaged displacement of approximately 1.65 cm was observed by applying ASTER-GDEM. Since displacements over outcrop area are considered to be apparent ones, the average could be a measure of flow rate estimation accuracy by DInSAR. Therefore, it is concluded that the accuracy of the ice flow rate measurement can be improved by using PRISM-DEM. In this presentation, we will show the results of the estimated flow rate of ice streams in the region of interest, and discuss the additional accuracy improvement of this method.
Large-scale time-series InSAR analysis of the Sacramento-San Joaquin delta subsidence using UAVSAR
NASA Astrophysics Data System (ADS)
Bekaert, D. P.; Jones, C. E.; An, K.; Huang, M. H.
2016-12-01
The Sacramento-San Joaquin delta (Delta) contains more than 1700 km of levees that protect various reclaimed lands from flooding. Most of the delta is experiencing subsidence at rates that can exceed 5 cm/yr locally, and which can affect the structural integrity of the levees. In-situ and airborne LIDAR monitoring of this extensive levee network is expensive, making Interferometric Synthetic Aperture Radar (InSAR) an attractive, cost-effective alternative that can provide uniform and consistent monitoring. InSAR has proven to be a powerful technique to study surface displacements at high accuracy (few mm/year), over large regions (up to 250 km wide swaths), and at a high spatial resolution (up to a meter). However widespread usage of InSAR, particularly within the application community, is challenged by several technical issues, the most significant of which are decorrelation noise introduced by a change of scattering properties (e.g., moisture and vegetation), and noise due to variation in atmospheric properties between different SAR acquisitions (i.e., tropospheric delay). These effects are particularly limiting in the rural/agricultural setting of the Delta. We demonstrate the usage of InSAR for spatially comprehensive subsidence monitoring both at the scale of the levees and at a scale that captures the intra-island variability. The study uses data collected over a period of six years (2009-2015) with NASA's Uninhabited Aerial Vehicle Synthetic Aperture Radar (UAVSAR) instrument, which is the prototype airborne instrument for the NISAR mission. We mitigate atmospheric noise by estimating a correction from state-of-the-art weather models, and reduce decorrelation noise by utilizing L-band SAR and using advanced time-series InSAR processing methods. Our analysis includes nine UAVSAR flight lines that cover altogether an area of approximately 8500 km2, including the Delta and the surrounding areas.
NASA Astrophysics Data System (ADS)
Kobayashi, T.; Yarai, H.; Morishita, Y.; Kawamoto, S.; Fujiwara, S.; Nakano, T.
2016-12-01
We report ground displacement associated with the 2016 Kumamoto Earthquake obtained by ALOS-2 SAR and GNSS data. For the SAR analyses, we applied InSAR, MAI, and pixel offset methods, which has successfully provided a 3D displacement field showing the widely- and locally-distributed deformation. The obtained displacement field shows clear displacement boundaries linearly along the Futagawa, the Hinagu, and the Denokuchi faults across which the sign of displacement component turns to be opposite, suggesting that the fault ruptures occurred there. Our fault model for the main shock suggests that the main rupture occurred on the Futagawa fault with a right-lateral motion including a slight normal fault motion. Due to the normal faulting movement, the northern side of the active fault subsides with approximately 2 m. The rupture on the Futagawa fault extends into the Aso caldera with slightly shifting the position northward. Of note, the fault plane oppositely dips toward southeast. It may be a conjugate fault against the main fault. In the western side of the Futagawa fault, the slip on the Hinagu fault, in which the Mj6.5 and Mj6.4 foreshocks occurred with a pure right-lateral motion, is also deeply involved with the main shock. This fault rupture released the amount of approximately 30 percent of the total seismic moment. The hypocenter is determined near the fault and its focal mechanism is consistent with the estimated slip motion of this fault plane, maybe suggesting that the rupture started at this fault and proceeded toward the Futagawa fault eastward. Acknowledgements: ALOS-2 data were provided from the Earthquake Working Group under a cooperative research contract with JAXA (Japan Aerospace Exploration Agency). The ownership of ALOS-2 data belongs to JAXA.
Estimating Velocities of Glaciers Using Sentinel-1 SAR Imagery
NASA Astrophysics Data System (ADS)
Gens, R.; Arnoult, K., Jr.; Friedl, P.; Vijay, S.; Braun, M.; Meyer, F. J.; Gracheva, V.; Hogenson, K.
2017-12-01
In an international collaborative effort, software has been developed to estimate the velocities of glaciers by using Sentinel-1 Synthetic Aperture Radar (SAR) imagery. The technique, initially designed by the University of Erlangen-Nuremberg (FAU), has been previously used to quantify spatial and temporal variabilities in the velocities of surging glaciers in the Pakistan Karakoram. The software estimates surface velocities by first co-registering image pairs to sub-pixel precision and then by estimating local offsets based on cross-correlation. The Alaska Satellite Facility (ASF) at the University of Alaska Fairbanks (UAF) has modified the software to make it more robust and also capable of migration into the Amazon Cloud. Additionally, ASF has implemented a prototype that offers the glacier tracking processing flow as a subscription service as part of its Hybrid Pluggable Processing Pipeline (HyP3). Since the software is co-located with ASF's cloud-based Sentinel-1 archive, processing of large data volumes is now more efficient and cost effective. Velocity maps are estimated for Single Look Complex (SLC) SAR image pairs and a digital elevation model (DEM) of the local topography. A time series of these velocity maps then allows the long-term monitoring of these glaciers. Due to the all-weather capabilities and the dense coverage of Sentinel-1 data, the results are complementary to optically generated ones. Together with the products from the Global Land Ice Velocity Extraction project (GoLIVE) derived from Landsat 8 data, glacier speeds can be monitored more comprehensively. Examples from Sentinel-1 SAR-derived results are presented along with optical results for the same glaciers.
Rapid Flood Map Generation from Spaceborne SAR Observations
NASA Astrophysics Data System (ADS)
Yun, S. H.; Liang, C.; Manipon, G.; Jung, J.; Gurrola, E. M.; Owen, S. E.; Hua, H.; Agram, P. S.; Webb, F.; Sacco, G. F.; Rosen, P. A.; Simons, M.
2016-12-01
The Advanced Rapid Imaging and Analysis (ARIA) team has responded to the January 2016 US Midwest Floods along the Mississippi River. Daily teleconferences with FEMA, NOAA, NGA, and USGS, provided information on precipitation and flood crest migration, based on which we coordinated with the Japanese Aerospace Exploration Agency (JAXA) through NASA headquarters for JAXA's ALOS-2 timely tasking over two paths. We produced flood extent maps using ALOS-2 SM3 mode Level 1.5 data that were provided through the International Charter and stored at the US Geological Survey's Hazards Data Distribution System (HDDS) archive. On January 6, the first four frames (70 km x 240 km) were acquired, which included the City of Memphis. We registered post-event SAR images to pre-event images, applied radiometric calibration, took a logarithm of the ratio of the two images. Two thresholds were applied to represent flooded areas that became open water (colored in blue) and flooded areas with tall vegetation (colored in red). The second path was acquired on January 11 further down along the Mississippi River. Seven frames (70 km x 420 km) were acquired and flood maps were created in the similar fashion. The maps were delivered to the FEMA as well as posted on ARIA's public website. The FEMA stated that SAR provides inspection priority for optical imagery and ground response. The ALOS-2 data and the products have been a very important source of information during this response as the flood crest has moved down stream. The SAR data continue to be an important resource during times when optical observations are often not useful. In close collaboration with FEMA and USGS, we also work on other flood events including June 2016 China Floods using European Space Agency's (ESA's) Sentienl-1 data, to produce flood extent maps and identify algorithmic needs and ARIA system's requirements to automate and rapidly produce and deliver flood maps for future events. With the addition of Sentinel-1B satellite, the composite expected wait time until a SAR satellite to fly over a flooded area became smaller than 12 hours. With more SAR missions, such as SAOCOM, RADARSAT Constellation, Sentinel-1C/D, ALOS-3, and NISAR, SAR data are becoming more useful for rapid mapping of devastating floods, which are becoming more frequent and more severe around the world.
Using InSAR Remote Sensing Technology to Analyze 3 Basin Aquifer Recharge Areas in Phoenix, Arizona
NASA Astrophysics Data System (ADS)
Smilovsky, D.; Rucker, M. L.
2016-12-01
Land subsidence due to pumping-induced groundwater decline has been well documented in alluviual basins in southern Arizona. Beginning in 2002, satellite-based interferometric synthetic aperture radar (InSAR) began to document post-1992 subsidence across these basins. Several basin aquifer recharge projects using water delivered by the Central Arizona Project (CAP) also began in the early 2000s. Reversal of land subsidence (elastic rebound) associated with recharge is evident in InSAR results across these basins. Projects with rebound documented using InSAR include the Tonopah Desert Recharge Project (permitted 150,000 [ac-ft/yr] starting in 2006) located 40 miles west of Phoenix, and the Hieroglyphic Mountains Recharge Project (permitted 35,000 ac-ft/yr starting in 2003) located several miles north of McMicken Dam in the West Salt River Valley. The Superstition Mountains Recharge Project (ultimate permitting of 85,000 ac-ft/yr, completed in 2011), located at Queen Creek in the East Salt River Valley, has also begun to develop a clear InSAR signature feature. Groundwater level index wells up to several miles downstream from these recharge facilities have indicated groundwater level recoveries of about 70 to 200 feet in the time corresponding to the InSAR studies. Resulting elastic rebound of ground surface elevations due to reduction of effective stresses in the compressible basin alluvium is a function of the effective stress change, the basin alluvium elastic moduli, and the thickness of the effected compressible basin alluvium. The areas and magnitudes of effective stress unloading are indicated from the rebound documented using InSAR. The volumes of aquifer recharge are anticipated to be related to the volumes of InSAR-derived rebound. It is also anticipated that estimates of large-scale horizontal hydraulic conductivity may be approximately verified by areas of ground surface rebound, and gradients driving groundwater flow may be inferred from magnitudes of rebound. These concepts are tested using documented recharge volumes, water level records at index wells, and concurrent InSAR results at the Tonopah and Hieroglyphic Mountains Recharge Projects, and basin alluvium moduli derived from subsidence studies associated with rehabilitation of McMicken Dam.
NASA Astrophysics Data System (ADS)
Bigdeli, Behnaz; Pahlavani, Parham
2017-01-01
Interpretation of synthetic aperture radar (SAR) data processing is difficult because the geometry and spectral range of SAR are different from optical imagery. Consequently, SAR imaging can be a complementary data to multispectral (MS) optical remote sensing techniques because it does not depend on solar illumination and weather conditions. This study presents a multisensor fusion of SAR and MS data based on the use of classification and regression tree (CART) and support vector machine (SVM) through a decision fusion system. First, different feature extraction strategies were applied on SAR and MS data to produce more spectral and textural information. To overcome the redundancy and correlation between features, an intrinsic dimension estimation method based on noise-whitened Harsanyi, Farrand, and Chang determines the proper dimension of the features. Then, principal component analysis and independent component analysis were utilized on stacked feature space of two data. Afterward, SVM and CART classified each reduced feature space. Finally, a fusion strategy was utilized to fuse the classification results. To show the effectiveness of the proposed methodology, single classification on each data was compared to the obtained results. A coregistered Radarsat-2 and WorldView-2 data set from San Francisco, USA, was available to examine the effectiveness of the proposed method. The results show that combinations of SAR data with optical sensor based on the proposed methodology improve the classification results for most of the classes. The proposed fusion method provided approximately 93.24% and 95.44% for two different areas of the data.
A general rough-surface inversion algorithm: Theory and application to SAR data
NASA Technical Reports Server (NTRS)
Moghaddam, M.
1993-01-01
Rough-surface inversion has significant applications in interpretation of SAR data obtained over bare soil surfaces and agricultural lands. Due to the sparsity of data and the large pixel size in SAR applications, it is not feasible to carry out inversions based on numerical scattering models. The alternative is to use parameter estimation techniques based on approximate analytical or empirical models. Hence, there are two issues to be addressed, namely, what model to choose and what estimation algorithm to apply. Here, a small perturbation model (SPM) is used to express the backscattering coefficients of the rough surface in terms of three surface parameters. The algorithm used to estimate these parameters is based on a nonlinear least-squares criterion. The least-squares optimization methods are widely used in estimation theory, but the distinguishing factor for SAR applications is incorporating the stochastic nature of both the unknown parameters and the data into formulation, which will be discussed in detail. The algorithm is tested with synthetic data, and several Newton-type least-squares minimization methods are discussed to compare their convergence characteristics. Finally, the algorithm is applied to multifrequency polarimetric SAR data obtained over some bare soil and agricultural fields. Results will be shown and compared to ground-truth measurements obtained from these areas. The strength of this general approach to inversion of SAR data is that it can be easily modified for use with any scattering model without changing any of the inversion steps. Note also that, for the same reason it is not limited to inversion of rough surfaces, and can be applied to any parameterized scattering process.
NASA Astrophysics Data System (ADS)
Hu, Jinyan; Li, Li; Yang, Yunfeng
2017-06-01
The hierarchical and successive approximate registration method of non-rigid medical image based on the thin-plate splines is proposed in the paper. There are two major novelties in the proposed method. First, the hierarchical registration based on Wavelet transform is used. The approximate image of Wavelet transform is selected as the registered object. Second, the successive approximation registration method is used to accomplish the non-rigid medical images registration, i.e. the local regions of the couple images are registered roughly based on the thin-plate splines, then, the current rough registration result is selected as the object to be registered in the following registration procedure. Experiments show that the proposed method is effective in the registration process of the non-rigid medical images.
SAR in human head model due to resonant wireless power transfer system.
Zhang, Chao; Liu, Guoqiang; Li, Yanhong; Song, Xianjin
2016-04-29
Efficient mid-range wireless power transfer between transmitter and the receiver has been achieved based on the magnetic resonant coupling method. The influence of electromagnetic field on the human body due to resonant wireless power transfer system (RWPT) should be taken into account during the design process of the system. To analyze the transfer performance of the RWPT system and the change rules of the specific absorption rate (SAR) in the human head model due to the RWPT system. The circuit-field coupling method for a RWPT system with consideration of the displacement current was presented. The relationship between the spiral coil parameters and transfer performance was studied. The SAR in the human head model was calculated under two different exposure conditions. A system with output power higher than 10 W at 0.2 m distance operating at a frequency of approximately 1 MHz was designed. The FEM simulation results show the peak SAR value is below the safety limit which appeared when the human head model is in front of the transmitter. The simulation results agreed well with the experimental results, which verified the validity of the analysis and design.
Interferometric synthetic aperture radar imagery of the Gulf Stream
NASA Technical Reports Server (NTRS)
Ainsworth, T. L.; Cannella, M. E.; Jansen, R. W.; Chubb, S. R.; Carande, R. E.; Foley, E. W.; Goldstein, R. M.; Valenzuela, G. R.
1993-01-01
The advent of interferometric synthetic aperture radar (INSAR) imagery brought to the ocean remote sensing field techniques used in radio astronomy. Whilst details of the interferometry differ between the two fields, the basic idea is the same: Use the phase information arising from positional differences of the radar receivers and/or transmitters to probe remote structures. The interferometric image is formed from two complex synthetic aperture radar (SAR) images. These two images are of the same area but separated in time. Typically the time between these images is very short -- approximately 50 msec for the L-band AIRSAR (Airborne SAR). During this short period the radar scatterers on the ocean surface do not have time to significantly decorrelate. Hence the two SAR images will have the same amplitude, since both obtain the radar backscatter from essentially the same object. Although the ocean surface structure does not significantly decorrelate in 50 msec, surface features do have time to move. It is precisely the translation of scattering features across the ocean surface which gives rise to phase differences between the two SAR images. This phase difference is directly proportional to the range velocity of surface scatterers. The constant of proportionality is dependent upon the interferometric mode of operation.
Assessment of specific energy absorption rate (SAR) in the head from a TETRA handset.
Dimbylow, Peter; Khalid, Mohammed; Mann, Simon
2003-12-07
Finite-difference time-domain (FDTD) calculations of the specific energy absorption rate (SAR) from a representative TETRA handset have been performed in an anatomically realistic model of the head. TETRA (Terrestrial Trunked Radio) is a modern digital private mobile radio system designed to meet the requirements of professional users, such as the police and fire brigade. The current frequency allocations in the UK are 380-385 MHz and 390-395 MHz for the public sector network. A comprehensive set of calculations of SAR in the head was performed for positions of the handset in front of the face and at both sides of the head. The representative TETRA handset considered. operating at 1 W in normal use, will show compliance with both the ICNIRP occupational and public exposure restrictions. The handset with a monopole antenna operating at 3 W in normal use will show compliance with both the ICNIRP occupational and public exposure restrictions. The handset with a helical antenna operating at 3 W in normal use will show compliance with the ICNIRP occupational exposure restriction but will be over the public exposure restriction by up to approximately 50% if kept in the position of maximum SAR for 6 min continuously.
Land subsidence in the Yangtze River Delta, China revealed from multi-frequency SAR Interferometry
NASA Astrophysics Data System (ADS)
Li, Zhenhong; Motagh, Mahdi; Yu, Jun; Gong, Xulong; Wu, Jianqiang; Zhu, Yefei; Chen, Huogen; Zhang, Dengming; Xu, Yulin
2014-05-01
Land subsidence is a major worldwide hazard, and its principal causes are subsurface fluid withdrawal, drainage of organic soils, sinkholes, underground mining, hydrocompaction, thawing permafrost, and natural consolidation. Land subsidence causes many problems including: damage to public facilities such as bridges, roads, railroads, electric power lines, underground pipes; damage to private and public buildings; and in some cases of low-lying land, can increase the risk of coastal flooding from storm surges and rising sea-levels. In China, approximately 48600 km2 of land, an area roughly 30 times of the size of the Greater London, has subsided (nearly 50 cities across 16 provinces), and the annual direct economic loss is estimated to be more than RMB 100 million (~12 million). It is believed that the Suzhou-Wuxi-Changzhou region within the Yangtze River Delta is the most severely affected area for subsidence hazards in China. With its global coverage and all-weather imaging capability, Interferometric SAR (InSAR) is revolutionizing our ability to image the Earth's surface and the evolution of its shape over time. In this paper, an advanced InSAR time series technique, InSAR TS + AEM, has been employed to analysed ERS (C-band), Envisat (C-band) and TerraSAR-X (X-band) data collected over the Suzhou-Wuxi-Changzhou region during the period from 1992 to 2013. Validation with precise levelling and GPS data suggest: (1) the accuracy of the InSAR-derived mean velocity measurements is 1-3 mm/yr; (2) InSAR-derived displacements agreed with precise levelling with root mean square errors around 5 mm. It is evident that InSAR TS + AEM can be used to image the evolution of deformation patterns in the Suzhou-Wuxi-Changzhou region over time: the maximum mean velocity decreased from ~12 cm/yr during the period of 1992-1993 to ~2 cm/yr in 2003-2013. This is believed to be a result of the prohibition of groundwater use carried out by Jiangsu provincial government. The combination of multi-frequency SAR datasets allows a long record (~20 years) of historic deformation to be measured over a large region. Ultimately this should help inform land managers in assessing land subsidence and planning appropriate remedial measures.
Bacterial diversity in the oxygen minimum zone of the eastern tropical South Pacific.
Stevens, Heike; Ulloa, Osvaldo
2008-05-01
The structure and diversity of bacterial communities associated with the oxygen minimum zone (OMZ) of the eastern tropical South Pacific was studied through phylogenetic analysis. Clone libraries of 16S rRNA gene fragments were constructed using environmental DNA collected from the OMZ (60 m and 200 m), the sea surface (10 m), and the deep oxycline (450 m). At the class level, the majority of sequences affiliated to the gamma- (53.7%) and alpha-Proteobacteria (19.7%), and to the Bacteroidetes (11.2%). A vertical partitioning of the bacterial communities was observed, with main differences between the suboxic OMZ and the more oxygenated surface and deep oxycline waters. At the surface, the microbial community was predominantly characterized by SAR86, Loktanella and unclassified Flavobacteriaceae, whereas the deeper layer was dominated by Sulfitobacter and unclassified Alteromonadaceae. In the OMZ, major constituents affiliated to the marine SAR11 clade and to thiotrophic gamma-symbionts (25% of all sequences), a group not commonly found in pelagic waters. Sequences affiliating to the phylum Chloroflexi, to the AGG47 and SAR202 clades, to the delta-Proteobacteria, to the Acidobacteria, and to the 'anammox group' of the Planctomycetes were found exclusively in the OMZ. The bacterial richness in the OMZ was higher than in the oxic surface and deeper oxycline, as revealed by rarefaction analysis and the Chao1 richness estimator (surface: 45 +/- 8, deeper oxycline: 76 +/- 26; OMZ (60 m): 97 +/- 33, OMZ (200 m): 109 +/- 31). OMZ bacterial diversity indices (Fisher's: approximately 30 +/- 5, Shannon's: approximately 3.31, inverse Simpson's: approximately 20) were similar to those found in other pelagic marine environments. Thus, our results indicate a distinct and diverse bacterial community within the OMZ, with presumably novel and yet uncultivated bacterial lineages.
On the use of InSAR technology to assess land subsidence in Jakarta coastal flood plain
NASA Astrophysics Data System (ADS)
Koudogbo, Fifame; Duro, Javier; Garcia Robles, Javier; Arnaud, Alain; Abidin, Hasanuddin Z.
2014-05-01
Jakarta is the capital of Indonesia and is home to approximately 10 million people on the coast of the Java Sea. It is situated on the northern coastal alluvial plane of Java which shares boundaries with West Java Province in the south and in the east, and with Banten Province in the west. The Capital District of Jakarta (DKI) sits in the lowest lying areas of the basin. Its topography varies, with the northern part just meters above current sea level and lying on a flood plain. Subsequently, this portion of the city frequently floods. The southern part of the city is hilly. Thirteen major rivers flow through Jakarta to the Java Sea. The Ciliwung River is the most significant river and divides the city West to East. In the last three decades, urban growing of Jakarta has been very fast in sectors as industry, trade, transportation, real estate, among others. This exponential development has caused several environmental issues; land subsidence is one of them. Subsidence in Jakarta has been known since the early part of the 20th century. It is mainly due to groundwater extraction, the fast development (construction load), soil natural consolidation and tectonics. Evidence of land subsidence exists through monitoring with GPS, level surveys and InSAR investigations. InSAR states for "Interferometric Synthetic Aperture Radar". Its principle is based on comparing the distance between the satellite and the ground in consecutive satellite passes over the same area on the Earth's surface. Radar satellites images record, with very high precision, the distance travelled by the radar signal that is emitted by the satellite is registered. When this distance is compared through time, InSAR technology can provide highly accurate ground deformation measurements. ALTAMIRA INFORMATION, company specialized in ground motion monitoring, has developed GlobalSARTM, which combines several processing techniques and algorithms based on InSAR technology, to achieve ground motion measurements with millimetric precision and high accuracy. World Bank studies conservatively estimate land subsidence in Jakarta occurring at an average rate of 5 cm per year, and in some areas, over 1 meters was already observed. Recent studies of land subsidence found that while typical subsidence rates were 7.5-10 cm a year, in localized areas of North Jakarta subsidence in the range 15-25 cm a year was occurring, which if sustained, would result in them sinking to 4 to 5 meters below sea level by 2025. Land subsidence will require major interventions, including increased pumping, dikes and most likely introducing major infrastructure investment for sea defense. With the increasing prevalence of Earth Observation, the World Bank and the European Space Agency have set up a partnership that aims at highlighting the potential of EO information to support the monitoring and management of World Bank projects. In this framework ALTAMIRA INFORMATION has assessed land subsidence in Jakarta. Impressive results have been obtained by providing high resolution measurements which can help in improving the characterization of the subsidence mechanisms.
Locating and defining underground goaf caused by coal mining from space-borne SAR interferometry
NASA Astrophysics Data System (ADS)
Yang, Zefa; Li, Zhiwei; Zhu, Jianjun; Yi, Huiwei; Feng, Guangcai; Hu, Jun; Wu, Lixin; Preusse, Alex; Wang, Yunjia; Papst, Markus
2018-01-01
It is crucial to locate underground goafs (i.e., mined-out areas) resulting from coal mining and define their spatial dimensions for effectively controlling the induced damages and geohazards. Traditional geophysical techniques for locating and defining underground goafs, however, are ground-based, labour-consuming and costly. This paper presents a novel space-based method for locating and defining the underground goaf caused by coal extraction using Interferometric Synthetic Aperture Radar (InSAR) techniques. As the coal mining-induced goaf is often a cuboid-shaped void and eight critical geometric parameters (i.e., length, width, height, inclined angle, azimuth angle, mining depth, and two central geodetic coordinates) are capable of locating and defining this underground space, the proposed method reduces to determine the eight geometric parameters from InSAR observations. Therefore, it first applies the Probability Integral Method (PIM), a widely used model for mining-induced deformation prediction, to construct a functional relationship between the eight geometric parameters and the InSAR-derived surface deformation. Next, the method estimates these geometric parameters from the InSAR-derived deformation observations using a hybrid simulated annealing and genetic algorithm. Finally, the proposed method was tested with both simulated and two real data sets. The results demonstrate that the estimated geometric parameters of the goafs are accurate and compatible overall, with averaged relative errors of approximately 2.1% and 8.1% being observed for the simulated and the real data experiments, respectively. Owing to the advantages of the InSAR observations, the proposed method provides a non-contact, convenient and practical method for economically locating and defining underground goafs in a large spatial area from space.
Findlay, R P; Dimbylow, P J
2009-04-21
If an antenna is located close to a person, the electric and magnetic fields produced by the antenna will vary in the region occupied by the human body. To obtain a mean value of the field for comparison with reference levels, the Institute of Electrical and Electronic Engineers (IEEE) and International Commission on Non-Ionizing Radiation Protection (ICNIRP) recommend spatially averaging the squares of the field strength over the height the body. This study attempts to assess the validity and accuracy of spatial averaging when used for half-wave dipoles at frequencies between 65 MHz and 2 GHz and distances of lambda/2, lambda/4 and lambda/8 from the body. The differences between mean electric field values calculated using ten field measurements and that of the true averaged value were approximately 15% in the 600 MHz to 2 GHz range. The results presented suggest that the use of modern survey equipment, which takes hundreds rather than tens of measurements, is advisable to arrive at a sufficiently accurate mean field value. Whole-body averaged and peak localized SAR values, normalized to calculated spatially averaged fields, were calculated for the NORMAN voxel phantom. It was found that the reference levels were conservative for all whole-body SAR values, but not for localized SAR, particularly in the 1-2 GHz region when the dipole was positioned very close to the body. However, if the maximum field is used for normalization of calculated SAR as opposed to the lower spatially averaged value, the reference levels provide a conservative estimate of the localized SAR basic restriction for all frequencies studied.
Søndergaard, Helle Bach; Brodin, Birger; Nielsen, Carsten Uhd
2008-06-01
The purpose of this work was to investigate the apical uptake and transepithelial transport of Gly-Sar along with the expression of the di-/tripeptide transporters hPEPT1 and hPEPT2 in human Calu-3 bronchial epithelial cells. The apical Gly-Sar uptake rate in Calu-3 cells followed Michaelis-Menten kinetics with a Km value of 1.3 +/- 0.3 mM and a Vmax value of 0.60 +/- 0.06 nmol cm(-2) min(-1). Transepithelial apical to basolateral transport of 50 microM [3H]-labelled Gly-Sar across the Calu-3 cell monolayer was pH-dependent. The Gly-Sar flux was significantly reduced in the presence of delta-aminolevulinic acid (2.5 mM), cephalexin (25 mM), and captopril (25 mM; p < 0.05, n = 3). Reverse transcriptase polymerase chain reaction (RT-PCR) revealed the presence of both hPEPT1 and hPEPT2 mRNA in the Calu-3 cells. These findings were confirmed in healthy human bronchial cDNA. Restriction-endonuclease analysis identified hPEPT2 in Calu-3 cells to be the hPEPT2*1 haplotype. Western blotting demonstrated expression of the hPEPT1 protein (approximately 80 kDa), and the immunolabel was mainly localized in the apical membrane as judged by immunolocalization studies using confocal laser scanning microscopy (CLSM). This work presents for the first time hPEPT1 and hPEPT2*1 expression in human Calu-3 cells. Surprisingly, the results indicate that Gly-Sar uptake and transport in Calu-3 cells are hPEPT1-mediated rather than hPEPT2-mediated.
Register of hydrogen technology experts
NASA Technical Reports Server (NTRS)
Ludtke, P. R.
1975-01-01
This register presents the names of approximately 235 individuals who are considered experts, or very knowledgeable, in various fields of technology related to hydrogen. Approximately 90 organizations are represented. Each person is listed by organizational affiliation, address, and principal area of expertise. The criteria for selection of names for the register are extensive experience in a given field of work, participation in or supervision of relevant research programs, contributions to the literature, or being recognized as an expert in a particular field. The purpose of the register is to present, in easy form, sources of dependable information regarding highly technical areas of hydrogen technology, with particular emphasis on safety. The register includes two indexes: an alphabetical listing of the experts and an alphabetical listing of the organizations with which they are affiliated.
Ship Signatures in RADARSAT-1 ScanSAR Narrow B Imagery: Analysis with AISLive Data
2007-03-01
desired target subscene contains image border “airballs” (i.e., the zero padded region around the image); • Multi-Signature Target Masking – A...of figures Figure 1. Histogram of latencies from AIS broadcast times by the originating vessels to the AISLive snapshot acquistion time for the... zero -th approximation, and first approximation courses are , , , and , respectively. The path length is a function of: a) the offset totalD iC fC
AIRSAR Web-Based Data Processing
NASA Technical Reports Server (NTRS)
Chu, Anhua; Van Zyl, Jakob; Kim, Yunjin; Hensley, Scott; Lou, Yunling; Madsen, Soren; Chapman, Bruce; Imel, David; Durden, Stephen; Tung, Wayne
2007-01-01
The AIRSAR automated, Web-based data processing and distribution system is an integrated, end-to-end synthetic aperture radar (SAR) processing system. Designed to function under limited resources and rigorous demands, AIRSAR eliminates operational errors and provides for paperless archiving. Also, it provides a yearly tune-up of the processor on flight missions, as well as quality assurance with new radar modes and anomalous data compensation. The software fully integrates a Web-based SAR data-user request subsystem, a data processing system to automatically generate co-registered multi-frequency images from both polarimetric and interferometric data collection modes in 80/40/20 MHz bandwidth, an automated verification quality assurance subsystem, and an automatic data distribution system for use in the remote-sensor community. Features include Survey Automation Processing in which the software can automatically generate a quick-look image from an entire 90-GB SAR raw data 32-MB/s tape overnight without operator intervention. Also, the software allows product ordering and distribution via a Web-based user request system. To make AIRSAR more user friendly, it has been designed to let users search by entering the desired mission flight line (Missions Searching), or to search for any mission flight line by entering the desired latitude and longitude (Map Searching). For precision image automation processing, the software generates the products according to each data processing request stored in the database via a Queue management system. Users are able to have automatic generation of coregistered multi-frequency images as the software generates polarimetric and/or interferometric SAR data processing in ground and/or slant projection according to user processing requests for one of the 12 radar modes.
SARS-CoV replicates in primary human alveolar type II cell cultures but not in type I-like cells
Mossel, Eric C.; Wang, Jieru; Jeffers, Scott; Edeen, Karen E.; Wang, Shuanglin; Cosgrove, Gregory P.; Funk, C. Joel; Manzer, Rizwan; Miura, Tanya A.; Pearson, Leonard D.; Holmes, Kathryn V.; Mason, Robert J.
2008-01-01
Severe acute respiratory syndrome (SARS) is a disease characterized by diffuse alveolar damage. We isolated alveolar type II cells and maintained them in a highly differentiated state. Type II cell cultures supported SARS-CoV replication as evidenced by RT-PCR detection of viral subgenomic RNA and an increase in virus titer. Virus titers were maximal by 24 hours and peaked at approximately 105 pfu/mL. Two cell types within the cultures were infected. One cell type was type II cells, which were positive for SP-A, SP-C, cytokeratin, a type II cell-specific monoclonal antibody, and Ep-CAM. The other cell type was composed of spindle-shaped cells that were positive for vimentin and collagen III and likely fibroblasts. Viral replication was not detected in type I-like cells or macrophages. Hence, differentiated adult human alveolar type II cells were infectible but alveolar type I-like cells and alveolar macrophages did not support productive infection. PMID:18022664
Evolution of Nonlinear Internal Waves in China Seas
NASA Technical Reports Server (NTRS)
Liu, Antony K.; Hsu, Ming-K.; Liang, Nai K.
1997-01-01
Synthetic Aperture Radar (SAR) images from ERS-I have been used to study the characteristics of internal waves of Taiwan in the East China Sea, and east of Hainan Island in the South China Sea. Rank-ordered packets of internal solitons propagating shoreward from the edge of the continental shelf were observed in the SAR images. Based on the assumption of a semidiurnal tidal origin, the wave speed can be estimated and is consistent with the internal wave theory. By using the SAR images and hydrographic data, internal waves of elevation have been identified in shallow water due to a thicker mixed layer as compared with the bottom layer on the continental shelf. The generation mechanism includes the influences of the tide and the Kuroshio intrusion across the continental shelf for the formations of elevation internal waves. The effects of water depth on the evolution of solitons and wave packets are modeled by nonlinear Kortweg-deVries (KdV) type equation and linked to satellite image observations. The numerical calculations of internal wave evolution on the continental shelf have been performed and compared with the SAR observations. For a case of depression waves in deep water, the solitons first disintegrate into dispersive wave trains and then evolve to a packet of elevation waves in the shallow water area after they pass through a turning point of approximately equal layer depths has been observed in the SAR image and simulated by numerical model.
Pre-2014 mudslides at Oso revealed by InSAR and multi-source DEM analysis
NASA Astrophysics Data System (ADS)
Kim, J. W.; Lu, Z.; QU, F.
2014-12-01
The landslide is a process that results in the downward and outward movement of slope-reshaping materials including rocks and soils and annually causes the loss of approximately $3.5 billion and tens of casualties in the United States. The 2014 Oso mudslide was an extreme event costing nearly 40 deaths and damaging civilian properties. Landslides are often unpredictable, but in many cases, catastrophic events are repetitive. Historic record in the Oso mudslide site indicates that there have been serial events in decades, though the extent of sliding events varied from time to time. In our study, the combination of multi-source DEMs, InSAR, and time-series InSAR analysis has enabled to characterize the Oso mudslide. InSAR results from ALOS PALSAR show that there was no significant deformation between mid-2006 and 2011. The combination of time-series InSAR analysis and old-dated DEM indicated revealed topographic changes associated the 2006 sliding event, which is confirmed by the difference of multiple LiDAR DEMs. Precipitation and discharge measurements before the 2006 and 2014 landslide events did not exhibit extremely anomalous records, suggesting the precipitation is not the controlling factor in determining the sliding events at Oso. The lack of surface deformation during 2006-2011 and weak correlation between the precipitation and the sliding event, suggest other factors (such as porosity) might play a critical role on the run-away events at this Oso and other similar landslides.
NASA Astrophysics Data System (ADS)
Lavalle, M.; Ahmed, R.
2014-12-01
Mapping forest structure and aboveground biomass globally is a major challenge that the remote sensing community has been facing for decades. Radar backscatter is sensitive to biomass only up to a certain amount (about 150 tons/ha at L-band and 300 tons/ha at P-band), whereas lidar remote sensing is strongly limited by poor spatial coverage. In recent years radar interferometry, including its extension to polarimetric radar interferometry (PolInSAR), has emerged as a new technique to overcome the limitations of radar backscatter. The idea of PolInSAR is to use jointly interferometric and polarimetric radar techniques to separate different scattering mechanisms and retrieve the vertical structure of forests. The advantage is to map ecosystem structure continuously over large areas and independently of cloud coverage. Experiments have shown that forest height - an important proxy for biomass - can be estimated using PolInSAR with accuracy between 15% and 20% at plot level. At AGU we will review the state-of-art of repeat-pass PolInSAR for biomass mapping, including its potential and limitations, and discuss how merging lidar data with PolInSAR data can be beneficial not only for product cross-validation but also for achieving better estimation of ecosystem properties over large areas. In particular, lidar data are expected to aid the inversion of PolInSAR models by providing (1) better identification of ground under the canopy, (2) approximate information of canopy structure in limited areas, and (3) maximum tree height useful for mapping PolInSAR temporal decorrelation. We will show our tree height and biomass maps using PolInSAR L-band JPL/UAVSAR data collected in tropical and temperate forests, and P-band ONERA/TROPISAR data acquired in French Guiana. LVIS lidar data will be used, as well as SRTM data, field measurements and inventory data to support our study. The use of two different radar frequencies and repeat-pass JPL UAVSAR data will offer also the opportunity to compare our results with the new airborne P-band ECOSAR and L-band DBSAR instruments developed at the NASA Goddard Space Flight Center.
From local to national scale DInSAR analysis for the comprehension of Earth's surface dynamics.
NASA Astrophysics Data System (ADS)
De Luca, Claudio; Casu, Francesco; Manunta, Michele; Zinno, Ivana; lanari, Riccardo
2017-04-01
Earth Observation techniques can be very helpful for the estimation of several sources of ground deformation due to their characteristics of large spatial coverage, high resolution and cost effectiveness. In this scenario, Differential Synthetic Aperture Radar Interferometry (DInSAR) is one of the most effective methodologies for its capability to generate spatially dense deformation maps with centimeter to millimeter accuracy. DInSAR exploits the phase difference (interferogram) between SAR image pairs relevant to acquisitions gathered at different times, but with the same illumination geometry and from sufficiently close flight tracks, whose separation is typically referred to as baseline. Among several, the SBAS algorithm is one of the most used DInSAR approaches and it is aimed at generating displacement time series at a multi-scale level by exploiting a set of small baseline interferograms. SBAS, and generally DInSAR, has taken benefit from the large availability of spaceborne SAR data collected along years by several satellite systems, with particular regard to the European ERS and ENVISAT sensors, which have acquired SAR images worldwide during approximately 20 years. While the application of SBAS to ERS and ENVISAT data at local scale is widely testified, very few examples involving those archives for analysis at huge spatial scale are available in literature. This is mainly due to the required processing power (in terms of CPUs, memory and storage) and the limited availability of automatic processing procedures (unsupervised tools), which are mandatory requirements for obtaining displacement results in a time effective way. Accordingly, in this work we present a methodology for generating the Vertical and Horizontal (East-West) components of Earth's surface deformation at very large (national/continental) spatial scale. In particular, it relies on the availability of a set of SAR data collected over an Area of Interest (AoI), which could be some hundreds of thousands of square kilometers wide, from ascending and descending orbits. The exploited SAR data are processed, on a local basis, through the Parallel SBAS (P-SBAS) approach thus generating the displacement time series and the corresponding mean deformation velocity maps. Subsequently, starting from the so generated DInSAR results, the proposed methodology lays on a proper mosaicking procedure to finally retrieve the mean velocity maps of the Vertical and Horizontal (East-West) deformation components relevant to the overall AoI. This technique permits to account for possible regional trends (tectonics trend) not easily detectable by the local scale DInSAR analyses. We tested the proposed methodology with the ENVISAT ASAR archives that have been acquired, from ascending and descending orbits, over California (US), covering an area of about 100.000 km2. The presented methodology can be easily applied also to other SAR satellite data. Above all, it is particularly suitable to deal with the very large data flow provided by the Sentinel-1 constellation, which collects data with a global coverage policy and an acquisition mode specifically designed for interferometric applications.
Episodic inflation of Akutan volcano, Alaska revealed from GPS and InSAR time series
NASA Astrophysics Data System (ADS)
DeGrandpre, K.; Lu, Z.; Wang, T.
2016-12-01
Akutan volcano is one of the most active volcanoes located long the Aleutian arc. At least 27 eruptions have been noted since 1790 and an intense swarm of volcano-tectonic earthquakes occurred in 1996. Surface deformation after the 1996 earthquake sequence has been studied using GPS and Interferometric Synthetic Aperture Radar (InSAR) separately, yet models created from these datasets require different mechanisms to produce the observed surface deformation: an inflating Mogi source results in the best approximation of displacement observed from GPS data, whereas an opening dyke is the best fit to deformation measured from InSAR. A recent study using seismic data revealed complex magmatic structures beneath the caldera, suggesting that the surface deformation may reflect more complicated mechanisms that cannot be estimated using one type of data alone. Here we integrate the surface deformation measured from GPS and InSAR to better understand the magma plumbing system beneath Akutan volcano. GPS time-series at 12 stations from 2006 to 2016 were analyzed, and two transient episodes of inflation in 2008 and 2014 were detected. These GPS stations are, however, too sparse to reveal the spatial distribution of the surface deformation. In order to better define the spatial extent of this inflation four tracks of Envisat data acquired during 2003-2010 and one track of TerraSAR-X data acquired from 2010 to 2016 were processed to produce high-resolution maps of surface deformation. These deformation maps show a consistently uplifting area on the northwestern flank of the volcano. We inverted for the source parameters required to produce the inflation using GPS, InSAR, and a dataset of GPS and InSAR measurements combined, to find that a deep Mogi source below a shallow dyke fit these datasets best. From the TerraSAR-X data, we were also able to measure the subsidence inside the summit caldera due to fumarole activity to be as high as 10 mm/yr. The complex spatial and temporal deformation patterns observed using GPS and InSAR at Akutan volcano imply that the magma plumbing system beneath the island inflates episodically from both deep and shallow sources of varying geometry which is responsible for the uplift observed in 2008 and 2014, but has yet led to an eruption.
PFM2: a 32 × 32 processor for X-ray diffraction imaging at FELs
NASA Astrophysics Data System (ADS)
Manghisoni, M.; Fabris, L.; Re, V.; Traversi, G.; Ratti, L.; Grassi, M.; Lodola, L.; Malcovati, P.; Vacchi, C.; Pancheri, L.; Benkechcache, M. E. A.; Dalla Betta, G.-F.; Xu, H.; Verzellesi, G.; Ronchin, S.; Boscardin, M.; Batignani, G.; Bettarini, S.; Casarosa, G.; Forti, F.; Giorgi, M.; Paladino, A.; Paoloni, E.; Rizzo, G.; Morsani, F.
2016-11-01
This work is concerned with the design of a readout chip for application to experiments at the next generation X-ray Free Electron Lasers (FEL). The ASIC, named PixFEL Matrix (PFM2), has been designed in a 65 nm CMOS technology and consists of 32 × 32 pixels. Each cell covers an area of 110 × 110 μm2 and includes a low-noise charge sensitive amplifier (CSA) with dynamic signal compression, a time-variant shaper used to process the preamplifier output signal, a 10-bit successive approximation register (SAR) analog-to-digital converter (ADC) and digital circuitry for channel control and data readout. Two different solutions for the readout channel, based on different versions of the time-variant filter, have been integrated in the chip. Both solutions can be operated in such a way to cope with the high frame rate (exceeding 1 MHz) foreseen for future X-ray FEL machines. The ASIC will be bump bonded to a slim/active edge pixel sensor to form the first demonstrator for the PixFEL X-ray imager. This work has been carried out in the frame of the PixFEL project funded by Istituto Nazionale di Fisica Nucleare (INFN), Italy.
Register of experts for information on mechanics of structural failure
NASA Technical Reports Server (NTRS)
Carpenter, J. L., Jr.; Moya, N.
1973-01-01
A list of approximately 150 experts from approximately 60 organizations who have published results of theoretical and/or experimental research related to six problem areas in the mechanics of structural failure is presented. Each author included is listed by organizational affiliation, address and principal field of expertise. The initial criteria for the selection of names for the register are recent contributions to the literature, participation in or support of relevant research programs, and referral by peers. The purpose of the register is to present, in easy reference form, sources for dependable information regarding failure modes and mechanisms of aerospace structures. The Register includes two indexes: an alphabetical listing of the experts and an alphabetical listing of the organizations with whom they are affiliated.
Lagrangian-based Backtracking of Oil Spill Dynamics from SAR Images: Application to Montara Case
NASA Astrophysics Data System (ADS)
Gautama, Budhi Gunadharma; Mercier, Gregoire; Fablet, Ronan; Longepe, Nicolas
2016-08-01
Within the framework of INDESO project (Infrastructure Development Space Oceanography), we address the issue of oilspill and aim at developing an operational SAR- based system for monitoring this issue in Indonesian waters from space. In this work, we focus on the backtrack- ing of an oilspill detected from SAR observations. As a case-study, we consider one large oil spill event that happened in Indonesian waters in 2009, referred to as the Montara oilspill. On 21 August 2009, the Montara Wellhead Platform had an uncontrolled release of hydrocarbons from one of the platform wells. It was estimated that 400 barrels (or approximately 64 tonnes) of crude oil were being lost per day. The uncontrolled release continued until 3 November 2009 and response operations continued until 3 December 2009. In this work, we develop a Langragian analysis and associated numerical inversion tools with a view to further analyzing the oil spread due to the Montara Wellhead Platform. Our model relies on a 2D Lagrangian transport model developed by CLS (Collecte Localisation Satellite). Our model involves four main parameters : the weights of wind- related and current-related advection, the origin and the duration of the oil leakage. Given SAR oilspill detections, we propose a numerical inversion of the parameters of the Lagrangian model, so that the simulated drift match the SAR observations of the oil spill. We demonstrate the relevance of the proposed model and numerical scheme for the Montara oilspill and further discuss their operational interest for the space-based oilspill backtracking and forecasting.
High-accuracy single-pass InSAR DEM for large-scale flood hazard applications
NASA Astrophysics Data System (ADS)
Schumann, G.; Faherty, D.; Moller, D.
2017-12-01
In this study, we used a unique opportunity of the GLISTIN-A (NASA airborne mission designed to characterizing the cryosphere) track to Greenland to acquire a high-resolution InSAR DEM of a large area in the Red River of the North Basin (north of Grand Forks, ND, USA), which is a very flood-vulnerable valley, particularly in spring time due to increased soil moisture content near state of saturation and/or, typical for this region, snowmelt. Having an InSAR DEM that meets flood inundation modeling and mapping requirements comparable to LiDAR, would demonstrate great application potential of new radar technology for national agencies with an operational flood forecasting mandate and also local state governments active in flood event prediction, disaster response and mitigation. Specifically, we derived a bare-earth DEM in SAR geometry by first removing the inherent far range bias related to airborne operation, which at the more typical large-scale DEM resolution of 30 m has a sensor accuracy of plus or minus 2.5 cm. Subsequently, an intelligent classifier based on informed relationships between InSAR height, intensity and correlation was used to distinguish between bare-earth, roads or embankments, buildings and tall vegetation in order to facilitate the creation of a bare-earth DEM that would meet the requirements for accurate floodplain inundation mapping. Using state-of-the-art LiDAR terrain data, we demonstrate that capability by achieving a root mean squared error of approximately 25 cm and further illustrating its applicability to flood modeling.
Yamazaki, Masaru; Ideta, Takahiro; Kudo, Sadahiro; Nakazawa, Masami
2016-06-01
In magnetic resonance imaging (MRI), when radiofrequency (RF) is irradiated to a subject with metallic implant, it can generate heat by RF irradiation. Recently 3 T MRI scanner has spread widely and imaging for any regions of whole body has been conducted. However specific absorption rate (SAR) of 3 T MRI becomes approximately four times as much as the 1.5 T, which can significantly affect the heat generation of metallic implants. So, we evaluated RF heating of artificial hip joints in different shapes and materials in 1.5 T and 3 T MRI. Three types of artificial hip joints made of stainless alloy, titanium alloy and cobalt chrome alloy were embedded in the human body-equivalent phantom respectively and their temperature change were measured for twenty minutes by 1.5 T and 3 T MRI. The maximum temperature rise was observed at the bottom head in all of three types of artificial hip joints, the rise being 12°C for stainless alloy, 11.9°C for titanium alloy and 6.1°C for cobalt chrome alloy in 1.5 T. The temperature rise depended on SAR and the increase of SAR had a good linear relationship with the temperature rise. It was found from the result that the RF heating of metallic implants can take place in various kinds of material and the increase of SAR has a good linear relationship with the temperature rise. This experience shows that reduction of SAR can decrease temperature of metallic implants.
Register of experts for information on mechanics of structural failure
NASA Technical Reports Server (NTRS)
Carpenter, J. L., Jr.; Stuhrke, W. F.
1975-01-01
This register is comprised of a list of approximately 300 experts from approximately 90 organizations who have published results of theoretical and/or experimental research related to six problem areas in the mechanics of structural failure: (1) life prediction for structural materials, (2) fracture toughness testing, (3) fracture mechanics analysis; (4) hydrogen embrittlement; (5) protective coatings; and (6) composite materials. The criteria for the selection of names for the register are recent contributions to the literature, participation in or support of relevant research programs, and referral by peers. Each author included is listed by organizational affiliation, address, and principal field of expertise. The purpose of the register is to present, in easy reference form, sources for dependable information regarding failure modes and mechanisms of aerospace structures. The register includes two indexes; an alphabetical listing of the experts and an alphabetical listing of the organizations with whom they are affiliated.
Chan, Sophia S C; So, Winnie K W; Wong, David C N; Lee, Angel C K; Tiwari, Agnes
2007-09-01
The outbreak of severe acute respiratory syndrome (SARS) in Hong Kong posed many challenges for health promotion activities among a group of older adults with low socio-economic status (SES). With concerns that this vulnerable group could be at higher risk of contracting the disease or spreading it to others, the implementation of health promotion activities appropriate to this group was considered to be essential during the epidemic. To assess the effectiveness of delivering a telephone health education programme dealing with anxiety levels, and knowledge and practice of measures to prevent transmission of SARS among a group of older adults with low SES. Pretest/posttest design. Subjects were recruited from registered members of a government subsidized social service center in Hong Kong and living in low-cost housing estates. The eligibility criteria were: (1) aged 55 or above; (2) able to speak Cantonese; (3) no hearing impairment, and (4) reachable by telephone. Of the 295 eligible subjects, 122 older adults completed the whole study. The interviewers approached all eligible subjects by telephone during the period of 15-25 May 2003. After obtaining the participants' verbal consent, the interviewer collected baseline data by use of a questionnaire and implemented a health education programme. A follow-up telephone call was made a week later using the same questionnaire. The level of anxiety was lowered (t=3.28, p<0.001), and knowledge regarding the transmission routes of droplets (p<0.001) and urine and feces (p<0.01) were improved after the intervention. Although statistical significant difference was found in the practice of identified preventive measures before and after intervention, influence on behavioral changes needed further exploration. The telephone health education seemed to be effective in relieving anxiety and improving knowledge of the main transmission routes of SARS in this group, but not the practice of preventing SARS. Telephone contact appears to be a practical way of providing health education to vulnerable groups when face-to-face measure is not feasible and may be useful in raising health awareness during future outbreaks of emerging infections.
Ionospheric effects on synthetic aperture radar at VHF
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fitzgerald, T.J.
1997-02-01
Synthetic aperture radars (SAR) operated from airplanes have been used at VHF because of their enhanced foliage and ground penetration compared to radars operated at UHF. A satellite-borne VHF SAR would have considerable utility but in order to operate with high resolution it would have to use both a large relative bandwidth and a large aperture. The presence of the ionosphere in the propagation path of the radar will cause a deterioration of the imaging because of dispersion over the bandwidth and group path changes in the imaged area over the collection aperture. In this paper we present calculations ofmore » the effects of a deterministic ionosphere on SAR imaging for a radar operated with a 100 MHz bandwidth centered at 250 MHz and over an angular aperture of 23{degrees}. The ionosphere induces a point spread function with an approximate half-width of 150 m in the slant-range direction and of 25 m in the cross-range direction compared to the nominal resolution of 1.5 m in both directions.« less
Uncertainty of InSAR velocity fields for measuring long-wavelength displacement
NASA Astrophysics Data System (ADS)
Fattahi, H.; Amelung, F.
2014-12-01
Long-wavelength artifacts in InSAR data are the main limitation to measure long-wavelength displacement; they are traditionally attributed mainly to the inaccuracy of the satellite orbits (orbital errors). However, most satellites are precisely tracked resulting in uncertainties of orbits of 2-10 cm. Orbits of these satellites are thus precise enough to obtain precise velocity fields with uncertainties better than 1 mm/yr/100 km for older satellites (e.g. Envisat) and better than 0.2 mm/yr/100 km for modern satellites (e.g. TerraSAR-X and Sentinel-1) [Fattahi & Amelung, 2014]. Such accurate velocity fields are achievable if long-wavelength artifacts from sources other than orbital errors are identified and corrected for. We present a modified Small Baseline approach to measure long-wavelength deformation and evaluate the uncertainty of these measurements. We use a redundant network of interferograms for detection and correction of unwrapping errors to ensure the unbiased estimation of phase history. We distinguish between different sources of long-wavelength artifacts and correct those introduced by atmospheric delay, topographic residuals, timing errors, processing approximations and hardware issues. We evaluate the uncertainty of the velocity fields using a covariance matrix with the contributions from orbital errors and residual atmospheric delay. For contributions from the orbital errors we consider the standard deviation of velocity gradients in range and azimuth directions as a function of orbital uncertainty. For contributions from the residual atmospheric delay we use several approaches including the structure functions of InSAR time-series epochs, the predicted delay from numerical weather models and estimated wet delay from optical imagery. We validate this InSAR approach for measuring long-wavelength deformation by comparing InSAR velocity fields over ~500 km long swath across the southern San Andreas fault system with independent GPS velocities and examine the estimated uncertainties in several non-deforming areas. We show the efficiency of the approach to study the continental deformation across the Chaman fault system at the western Indian plate boundary. Ref: Fattahi, H., & Amelung, F., (2014), InSAR uncertainty due to orbital errors, Geophys, J. Int (in press).
InSAR Scientific Computing Environment - The Home Stretch
NASA Astrophysics Data System (ADS)
Rosen, P. A.; Gurrola, E. M.; Sacco, G.; Zebker, H. A.
2011-12-01
The Interferometric Synthetic Aperture Radar (InSAR) Scientific Computing Environment (ISCE) is a software development effort in its third and final year within the NASA Advanced Information Systems and Technology program. The ISCE is a new computing environment for geodetic image processing for InSAR sensors enabling scientists to reduce measurements directly from radar satellites to new geophysical products with relative ease. The environment can serve as the core of a centralized processing center to bring Level-0 raw radar data up to Level-3 data products, but is adaptable to alternative processing approaches for science users interested in new and different ways to exploit mission data. Upcoming international SAR missions will deliver data of unprecedented quantity and quality, making possible global-scale studies in climate research, natural hazards, and Earth's ecosystem. The InSAR Scientific Computing Environment has the functionality to become a key element in processing data from NASA's proposed DESDynI mission into higher level data products, supporting a new class of analyses that take advantage of the long time and large spatial scales of these new data. At the core of ISCE is a new set of efficient and accurate InSAR algorithms. These algorithms are placed into an object-oriented, flexible, extensible software package that is informed by modern programming methods, including rigorous componentization of processing codes, abstraction and generalization of data models. The environment is designed to easily allow user contributions, enabling an open source community to extend the framework into the indefinite future. ISCE supports data from nearly all of the available satellite platforms, including ERS, EnviSAT, Radarsat-1, Radarsat-2, ALOS, TerraSAR-X, and Cosmo-SkyMed. The code applies a number of parallelization techniques and sensible approximations for speed. It is configured to work on modern linux-based computers with gcc compilers and python. ISCE is now a complete, functional package, under configuration management, and with extensive documentation and tested use cases appropriate to geodetic imaging applications. The software has been tested with canonical simulated radar data ("point targets") as well as with a variety of existing satellite data, cross-compared with other software packages. Its extensibility has already been proven by the straightforward addition of polarimetric processing and calibration, and derived filtering and estimation routines associated with polarimetry that supplement the original InSAR geodetic functionality. As of October 2011, the software is available for non-commercial use through UNAVCO's WinSAR consortium.
Integrated Shoreline Extraction Approach with Use of Rasat MS and SENTINEL-1A SAR Images
NASA Astrophysics Data System (ADS)
Demir, N.; Oy, S.; Erdem, F.; Şeker, D. Z.; Bayram, B.
2017-09-01
Shorelines are complex ecosystems and highly important socio-economic environments. They may change rapidly due to both natural and human-induced effects. Determination of movements along the shoreline and monitoring of the changes are essential for coastline management, modeling of sediment transportation and decision support systems. Remote sensing provides an opportunity to obtain rapid, up-to-date and reliable information for monitoring of shoreline. In this study, approximately 120 km of Antalya-Kemer shoreline which is under the threat of erosion, deposition, increasing of inhabitants and urbanization and touristic hotels, has been selected as the study area. In the study, RASAT pansharpened and SENTINEL-1A SAR images have been used to implement proposed shoreline extraction methods. The main motivation of this study is to combine the land/water body segmentation results of both RASAT MS and SENTINEL-1A SAR images to improve the quality of the results. The initial land/water body segmentation has been obtained using RASAT image by means of Random Forest classification method. This result has been used as training data set to define fuzzy parameters for shoreline extraction from SENTINEL-1A SAR image. Obtained results have been compared with the manually digitized shoreline. The accuracy assessment has been performed by calculating perpendicular distances between reference data and extracted shoreline by proposed method. As a result, the mean difference has been calculated around 1 pixel.
NASA Astrophysics Data System (ADS)
Liu, Shuanglong; Vorobyova, Ivetta; Park, Ryan; Conti, Peter S.
2017-10-01
Introduction: 64Cu-BaBaSar-RGD2 is a positron emission radiotracer taken up by integrin αvβ3, which is overexpressed in many malignancies. The aim of this study was to evaluate the biodistribution of 64Cu-BaBaSar-RGD2 in a non-human primate with positron emission tomography and to estimate the absorbed doses in major organs for human. Materials and methods: Whole-body PET imaging was done in a Siemens Biograph scanner in a male macaque monkey. After an i.v. injection of 13.1–19.7 MBq/kg of 64Cu-BaBaSar-RGD2, whole body scan was collected for a total duration of 180 min. Attenuation and scatter corrections were applied to reconstruction of the whole-body emission scan. After image reconstruction, three-dimensional volumes of interest (VOI) were hand-drawn on the PET transaxial or coronal slices of the frame where the organ was most conspicuous. Time-activity curves for each VOI were obtained, and residence time of each organ was calculated by integration of the time-activity curves. Human absorbed doses were estimated using the standard human model in OLINDA/EXM software. Results: Injection of 64Cu-BaBaSar-RGD2 was well tolerated in the macaque monkey, with no serious tracer-related adverse events observed. 64Cu-BaBaSar-RGD2 was cleared rapidly from the blood pool, with a 12.1-min biological half-time. Increased 64Cu-BaBaSar-RGD2 uptake was observed in the kidneys, and bladder, with mean percentage injected dose (ID%) values at 1 h after injection approximately 35.50 ± 6.47 and 36.89 ± 5.48, respectively. The calculated effective dose was 15.30 ± 2.21 µSv/MBq, and the kidneys had the highest absorbed dose at 108.43 ± 16.41 µGy/MBq using the non-voiding model. For an injected activity of 925 MBq 64Cu for human, the effective dose would be 14.2 ± 2.1 mSv. Discussion: Due to the limitation of the monkey number, we evaluated 64Cu-BaBaSar-RGD2 in the same monkey of three imaging sessions. Measured absorbed doses and effective doses of 64Cu-BaBaSar-RGD2 are comparable to other reported RGD-derived radiopharmaceuticals labeled with 64Cu and 18F. Therefore, 64Cu-BaBaSar-RGD2 can be safely injected into humans for studying integrin αvβ3 expression non-invasively.
NASA Astrophysics Data System (ADS)
Liorni, I.; Parazzini, M.; Varsier, N.; Hadjem, A.; Ravazzani, P.; Wiart, J.
2016-04-01
So far, the assessment of the exposure of children, in the ages 0-2 years old, to relatively new radio-frequency (RF) technologies, such as tablets and femtocells, remains an open issue. This study aims to analyse the exposure of a one year-old child to these two sources, tablets and femtocells, operating in uplink (tablet) and downlink (femtocell) modes, respectively. In detail, a realistic model of an infant has been used to model separately the exposures due to (i) a 3G tablet emitting at the frequency of 1940 MHz (uplink mode) placed close to the body and (ii) a 3G femtocell emitting at 2100 MHz (downlink mode) placed at a distance of at least 1 m from the infant body. For both RF sources, the input power was set to 250 mW. The variability of the exposure due to the variation of the position of the RF sources with respect to the infant body has been studied by stochastic dosimetry, based on polynomial chaos to build surrogate models of both whole-body and tissue specific absorption rate (SAR), which makes it easy and quick to investigate the exposure in a full range of possible positions of the sources. The major outcomes of the study are: (1) the maximum values of the whole-body SAR (WB SAR) have been found to be 9.5 mW kg-1 in uplink mode and 65 μW kg-1 in downlink mode, i.e. within the limits of the ICNIRP 1998 Guidelines; (2) in both uplink and downlink mode the highest SAR values were approximately found in the same tissues, i.e. in the skin, eye and penis for the whole-tissue SAR and in the bone, skin and muscle for the peak SAR; (3) the change in the position of both the 3G tablet and the 3G femtocell significantly influences the infant exposure.
NASA Astrophysics Data System (ADS)
McAlpin, D. B.; Meyer, F. J.; Lu, Z.; Beget, J. E.
2014-12-01
Augustine Island is a small, 8x11 km island in South Central Alaska's lower Cook Inlet. It is approximately 280 km southwest of Anchorage, and occupied entirely by its namesake Augustine Volcano. At Augustine Volcano, SAR data suitable for interferometry is available from 1992 to 2005, from March 2006 to April 2007, and from July 2007 to October 2010. Its last two eruptive episodes, in 1986 and 2006, resulted in substantial pyroclastic flow deposits (PFDs) on the Volcano's north flank. Earlier InSAR analyses of the area, from 1992-1999, identified local subsidence, but no volcano-wide deformation indicative of magma-chamber evacuation. In contrast to previous studies, we use InSAR data to determine a range of geophysical parameters for PFDs emplaced during the Augustine's two most recent eruption cycles. Based on InSAR measurements between 1992 and 2010, we reconstruct the deformation behavior of PFDs emplaced during Augustine's last two eruption cycles. Using a combination of InSAR measurements and modeling, we determine the thickness and long-term deformation of overlaying pyroclastic flow deposits emplaced in 1986 and 2006. Consistent with previous observations of pyroclastic flows, we found that the PFDs on Augustine Island rapidly subsided after emplacement due to an initial compaction of the material. We determined the length of this initial settling period and measured the compaction rate. Subsequent to this initial rapid subsidence, we found that PFD deformation slowed to a more persistent, linear, long-term rate, related to cooling of the deposits. We established that the deposits' contraction rate is linearly related to their thickness and measured the contraction rate. Finally, a study of long term coherence properties of the Augustine PFDs showed remarkable stability of the surface over long time periods. This information provides clues on the structural properties and composition of the emplaced material.
Influence of the external DEM on PS-InSAR processing and results on Northern Appennine slopes
NASA Astrophysics Data System (ADS)
Bayer, B.; Schmidt, D. A.; Simoni, A.
2014-12-01
We present an InSAR analysis of slow moving landslide in the Northern Appennines, Italy, and assess the dependencies on the choice of DEM. In recent years, advanced processing techniques for synthetic aperture radar interferometry (InSAR) have been applied to measure slope movements. The persistent scatterers (PS-InSAR) approach is probably the most widely used and some codes are now available in the public domain. The Stanford method of Persistent Scatterers (StamPS) has been successfully used to analyze landslide areas. One problematic step in the processing chain is the choice of an external DEM that is used to model and remove the topographic phase in a series of interferograms in order to obtain the phase contribution caused by surface deformation. The choice is not trivial, because the PS InSAR results differ significantly in terms of PS identification, positioning, and the resulting deformation signal. We use four different DEMs to process a set of 18 ASAR (Envisat) scenes over a mountain area (~350 km2) of the Northern Appennines of Italy, using StamPS. Slow-moving landslides control the evolution of the landscape and cover approximately 30% of the territory. Our focus in this presentation is to evaluate the influence of DEM resolution and accuracy by comparing PS-InSAR results. On an areal basis, we perform a statistical analysis of displacement time-series to make the comparison. We also consider two case studies to illustrate the differences in terms of PS identification, number and estimated displacements. It is clearly shown that DEM accuracy positively influences the number of PS, while line-of-sight rates differ from case to case and can result in deformation signals that are difficult to interpret. We also take advantage of statistical tools to analyze the obtained time-series datasets for the whole study area. Results indicate differences in the style and amount of displacement that can be related to the accuracy of the employed DEM.
Liorni, I; Parazzini, M; Varsier, N; Hadjem, A; Ravazzani, P; Wiart, J
2016-04-21
So far, the assessment of the exposure of children, in the ages 0-2 years old, to relatively new radio-frequency (RF) technologies, such as tablets and femtocells, remains an open issue. This study aims to analyse the exposure of a one year-old child to these two sources, tablets and femtocells, operating in uplink (tablet) and downlink (femtocell) modes, respectively. In detail, a realistic model of an infant has been used to model separately the exposures due to (i) a 3G tablet emitting at the frequency of 1940 MHz (uplink mode) placed close to the body and (ii) a 3G femtocell emitting at 2100 MHz (downlink mode) placed at a distance of at least 1 m from the infant body. For both RF sources, the input power was set to 250 mW. The variability of the exposure due to the variation of the position of the RF sources with respect to the infant body has been studied by stochastic dosimetry, based on polynomial chaos to build surrogate models of both whole-body and tissue specific absorption rate (SAR), which makes it easy and quick to investigate the exposure in a full range of possible positions of the sources. The major outcomes of the study are: (1) the maximum values of the whole-body SAR (WB SAR) have been found to be 9.5 mW kg(-1) in uplink mode and 65 μW kg(-1) in downlink mode, i.e. within the limits of the ICNIRP 1998 Guidelines; (2) in both uplink and downlink mode the highest SAR values were approximately found in the same tissues, i.e. in the skin, eye and penis for the whole-tissue SAR and in the bone, skin and muscle for the peak SAR; (3) the change in the position of both the 3G tablet and the 3G femtocell significantly influences the infant exposure.
Depth varying rupture properties during the 2015 Mw 7.8 Gorkha (Nepal) earthquake
NASA Astrophysics Data System (ADS)
Yue, Han; Simons, Mark; Duputel, Zacharie; Jiang, Junle; Fielding, Eric; Liang, Cunren; Owen, Susan; Moore, Angelyn; Riel, Bryan; Ampuero, Jean Paul; Samsonov, Sergey V.
2017-09-01
On April 25th 2015, the Mw 7.8 Gorkha (Nepal) earthquake ruptured a portion of the Main Himalayan Thrust underlying Kathmandu and surrounding regions. We develop kinematic slip models of the Gorkha earthquake using both a regularized multi-time-window (MTW) approach and an unsmoothed Bayesian formulation, constrained by static and high rate GPS observations, synthetic aperture radar (SAR) offset images, interferometric SAR (InSAR), and teleseismic body wave records. These models indicate that Kathmandu is located near the updip limit of fault slip and approximately 20 km south of the centroid of fault slip. Fault slip propagated unilaterally along-strike in an ESE direction for approximately 140 km with a 60 km cross-strike extent. The deeper portions of the fault are characterized by a larger ratio of high frequency (0.03-0.2 Hz) to low frequency slip than the shallower portions. From both the MTW and Bayesian results, we can resolve depth variations in slip characteristics, with higher slip roughness, higher rupture velocity, longer rise time and higher complexity of subfault source time functions in the deeper extents of the rupture. The depth varying nature of rupture characteristics suggests that the up-dip portions are characterized by relatively continuous rupture, while the down-dip portions may be better characterized by a cascaded rupture. The rupture behavior and the tectonic setting indicate that the earthquake may have ruptured both fully seismically locked and a deeper transitional portions of the collision interface, analogous to what has been seen in major subduction zone earthquakes.
Structural Health Monitoring of Railway Transition Zones Using Satellite Radar Data.
Wang, Haoyu; Chang, Ling; Markine, Valeri
2018-01-31
Transition zones in railway tracks are locations with considerable changes in the rail-supporting structure. Typically, they are located near engineering structures, such as bridges, culverts and tunnels. In such locations, severe differential settlements often occur due to the different material properties and structure behavior. Without timely maintenance, the differential settlement may lead to the damage of track components and loss of passenger's comfort. To ensure the safety of railway operations and reduce the maintenance costs, it is necessary to consecutively monitor the structural health condition of the transition zones in an economical manner and detect the changes at an early stage. However, using the current in situ monitoring of transition zones is hard to achieve this goal, because most in situ techniques (e.g., track-measuring coaches) are labor-consuming and usually not frequently performed (approximately twice a year in the Netherlands). To tackle the limitations of the in situ techniques, a Satellite Synthetic Aperture Radar (InSAR) system is presented in this paper, which provides a potential solution for a consecutive structural health monitoring of transition zones with bi-/tri-weekly data update and mm-level precision. To demonstrate the feasibility of the InSAR system for monitoring transition zones, a transition zone is tested. The results show that the differential settlement in the transition zone and the settlement rate can be observed and detected by the InSAR measurements. Moreover, the InSAR results are cross-validated against measurements obtained using a measuring coach and a Digital Image Correlation (DIC) device. The results of the three measuring techniques show a good correlation, which proves the applicability of InSAR for the structural health monitoring of transition zones in railway track.
Structural Health Monitoring of Railway Transition Zones Using Satellite Radar Data
Chang, Ling; Markine, Valeri
2018-01-01
Transition zones in railway tracks are locations with considerable changes in the rail-supporting structure. Typically, they are located near engineering structures, such as bridges, culverts and tunnels. In such locations, severe differential settlements often occur due to the different material properties and structure behavior. Without timely maintenance, the differential settlement may lead to the damage of track components and loss of passenger’s comfort. To ensure the safety of railway operations and reduce the maintenance costs, it is necessary to consecutively monitor the structural health condition of the transition zones in an economical manner and detect the changes at an early stage. However, using the current in situ monitoring of transition zones is hard to achieve this goal, because most in situ techniques (e.g., track-measuring coaches) are labor-consuming and usually not frequently performed (approximately twice a year in the Netherlands). To tackle the limitations of the in situ techniques, a Satellite Synthetic Aperture Radar (InSAR) system is presented in this paper, which provides a potential solution for a consecutive structural health monitoring of transition zones with bi-/tri-weekly data update and mm-level precision. To demonstrate the feasibility of the InSAR system for monitoring transition zones, a transition zone is tested. The results show that the differential settlement in the transition zone and the settlement rate can be observed and detected by the InSAR measurements. Moreover, the InSAR results are cross-validated against measurements obtained using a measuring coach and a Digital Image Correlation (DIC) device. The results of the three measuring techniques show a good correlation, which proves the applicability of InSAR for the structural health monitoring of transition zones in railway track. PMID:29385070
Campbell-Washburn, Adrienne E; Rogers, Toby; Stine, Annette M; Khan, Jaffar M; Ramasawmy, Rajiv; Schenke, William H; McGuirt, Delaney R; Mazal, Jonathan R; Grant, Laurie P; Grant, Elena K; Herzka, Daniel A; Lederman, Robert J
2018-06-21
Cardiovascular magnetic resonance (CMR) fluoroscopy allows for simultaneous measurement of cardiac function, flow and chamber pressure during diagnostic heart catheterization. To date, commercial metallic guidewires were considered contraindicated during CMR fluoroscopy due to concerns over radiofrequency (RF)-induced heating. The inability to use metallic guidewires hampers catheter navigation in patients with challenging anatomy. Here we use low specific absorption rate (SAR) imaging from gradient echo spiral acquisitions and a commercial nitinol guidewire for CMR fluoroscopy right heart catheterization in patients. The low-SAR imaging protocol used a reduced flip angle gradient echo acquisition (10° vs 45°) and a longer repetition time (TR) spiral readout (10 ms vs 2.98 ms). Temperature was measured in vitro in the ASTM 2182 gel phantom and post-mortem animal experiments to ensure freedom from heating with the selected guidewire (150 cm × 0.035″ angled-tip nitinol Terumo Glidewire). Seven patients underwent CMR fluoroscopy catheterization. Time to enter each chamber (superior vena cava, main pulmonary artery, and each branch pulmonary artery) was recorded and device visibility and confidence in catheter and guidewire position were scored on a Likert-type scale. Negligible heating (< 0.07°C) was observed under all in vitro conditions using this guidewire and imaging approach. In patients, chamber entry was successful in 100% of attempts with a guidewire compared to 94% without a guidewire, with failures to reach the branch pulmonary arteries. Time-to-enter each chamber was similar (p=NS) for the two approaches. The guidewire imparted useful catheter shaft conspicuity and enabled interactive modification of catheter shaft stiffness, however, the guidewire tip visibility was poor. Under specific conditions, trained operators can apply low-SAR imaging and using a specific fully-insulated metallic nitinol guidewire (150 cm × 0.035" Terumo Glidewire) to augment clinical CMR fluoroscopy right heart catheterization. Clinicaltrials.gov NCT03152773 , registered May 15, 2017.
Preliminary studies: far-field microwave dosimetric measurements of a full-scale model of man.
Olsen, R G
1979-12-01
Measurements of microwave heating were made in a full-size, upright human model. The 75-Kg model, composed of electrically simulated muscle, was placed in the far-zone of a standard-gain horn inside an absorber-lined chamber. Pulsed energy at 1.29 GHz was obtained from a military radar transmitter (AN/TPS-1G) and produced radiation at 6-14 mW/cm2 average power density at the location of the model. Microwave heating at the front surface was measured at nine locations on the phantom. Measurements at several depths within the phantom were also made at a central location to gain information on the depth-of-penetration of the microwave energy. Results of the frontal surface measurements and of the penetration study permitted a calculation of the approximate whole-body average specific absorption rate (SAR) when the model's long axis was parallel to the E-field vector. For a normalized power density of 1 mW/cm2 at a frequency of 1.29 GHz, the whole-body average SAR approximated 0.03 W/Kg. This result agrees well with theoretical predictions based on absorption in prolate spheroidal models of man.
Unsupervised DInSAR processing chain for multi-scale displacement analysis
NASA Astrophysics Data System (ADS)
Casu, Francesco; Manunta, Michele
2016-04-01
Earth Observation techniques can be very helpful for the estimation of several sources of ground deformation due to their characteristics of large spatial coverage, high resolution and cost effectiveness. In this scenario, Differential Synthetic Aperture Radar Interferometry (DInSAR) is one of the most effective methodologies for its capability to generate spatially dense deformation maps at both global and local spatial scale, with centimeter to millimeter accuracy. DInSAR exploits the phase difference (interferogram) between SAR image pairs relevant to acquisitions gathered at different times, but with the same illumination geometry and from sufficiently close flight tracks, whose separation is typically referred to as baseline. Among several, the SBAS algorithm is one of the most used DInSAR approaches and it is aimed at generating displacement time series at a multi-scale level by exploiting a set of small baseline interferograms. SBAS, and generally DInSAR, has taken benefit from the large availability of spaceborne SAR data collected along years by several satellite systems, with particular regard to the European ERS and ENVISAT sensors, which have acquired SAR images worldwide during approximately 20 years. Moreover, since 2014 the new generation of Copernicus Sentinel satellites has started to acquire data with a short revisit time (12 days) and a global coverage policy, thus flooding the scientific EO community with an unprecedent amount of data. To efficiently manage such amount of data, proper processing facilities (as those coming from the emerging Cloud Computing technologies) have to be used, as well as novel algorithms aimed at their efficient exploitation have to be developed. In this work we present a set of results achieved by exploiting a recently proposed implementation of the SBAS algorithm, namely Parallel-SBAS (P-SBAS), which allows us to effectively process, in an unsupervised way and in a limited time frame, a huge number of SAR images, thus leading to the generation of Interferometric products for both global and local scale displacement analysis. Among several examples, we will show a wide displacement SBAS processing, carried out over the southern California, during which the whole ascending ENVISAT data set of more than 740 images has been fully processed on a Cloud Computing environment in less than 9 hours, leading to the generation of a displacement map of about 150,000 square kilometres. The P-SBAS characteristics allowed also us to integrate the algorithm within the ESA Geohazard Exploitation Platform (GEP), which is based on the use of GRID and Cloud Computing facilities, thus making freely available to the EO community a web tool for massive and systematic interferometric displacement time series generation. This work has been partially supported by: the Italian MIUR under the RITMARE project; the CNR-DPC agreement and the ESA GEP project.
The protective effects of ginsenosides on human erythrocytes against hemin-induced hemolysis.
Li, Guo-Xiang; Liu, Zai-Qun
2008-03-01
Panax ginseng has been used in traditional Chinese medicine to enhance stamina and capacity to deal with fatigue and physical stress. Many reports have been devoted to the effects of ginsenosides on many in vitro or in vivo experimental systems. The major aim of this work is to investigate the protective effects of 12 individual ginsenosides including Rb1, Rb3, Rc, Rd, Re, Rg1, Rg2, Rg3, Rh1, Rh2, R1 and pseudoginsenoside F11, together with the central structures of aforementioned ginsenosides, 20(S)-protopanaxadiol (PD) and 20(S)-protopanaxatriol (PT), on hemin-induced hemolysis of human erythrocytes. This is because hemin can induce hemolysis by accelerating the potassium leakage, dissociating skeletal proteins and prohibiting some enzymes in the membrane of erythrocyte. Thus, the structure-activity-relationship (SAR) between ginsenosides and protective effects has been screened in this in vitro experimental system. It is found that Rh2 and Rg3 intensify hemolysis in the presence of hemin, and initiate hemolysis even in the absence of hemin. All the other ginsenosides protect human erythrocytes against hemin-induced hemolysis more or less. The overall sequence is Rc>Rd>Re approximately Rb1>Rg1 approximately Rh1>Rb3 approximately Rg2 approximately R1 approximately F11 approximately PT. In addition, the protective effects of PD and PT have been detected, and found that PD promotes hemolysis appreciably, whereas PT protects erythrocytes efficiently. Moreover, the protective effects of PT ginsenosides are similar to PT itself, and the protective effects of PD ginsenosides vary remarkably, demonstrating that the positions of the sugar moieties make the protective activities of ginsenosides complicated. Especially, sugar moiety at 20-position is critical for PD ginsenosides to inhibit hemolysis, whereas hydroxyl group at 3-position is important for PT ginsenosides. The present result may be useful for understanding the SAR of ginsenosides.
On the estimation of the worst-case implant-induced RF-heating in multi-channel MRI.
Córcoles, Juan; Zastrow, Earl; Kuster, Niels
2017-06-21
The increasing use of multiple radiofrequency (RF) transmit channels in magnetic resonance imaging (MRI) systems makes it necessary to rigorously assess the risk of RF-induced heating. This risk is especially aggravated with inclusions of medical implants within the body. The worst-case RF-heating scenario is achieved when the local tissue deposition in the at-risk region (generally in the vicinity of the implant electrodes) reaches its maximum value while MRI exposure is compliant with predefined general specific absorption rate (SAR) limits or power requirements. This work first reviews the common approach to estimate the worst-case RF-induced heating in multi-channel MRI environment, based on the maximization of the ratio of two Hermitian forms by solving a generalized eigenvalue problem. It is then shown that the common approach is not rigorous and may lead to an underestimation of the worst-case RF-heating scenario when there is a large number of RF transmit channels and there exist multiple SAR or power constraints to be satisfied. Finally, this work derives a rigorous SAR-based formulation to estimate a preferable worst-case scenario, which is solved by casting a semidefinite programming relaxation of this original non-convex problem, whose solution closely approximates the true worst-case including all SAR constraints. Numerical results for 2, 4, 8, 16, and 32 RF channels in a 3T-MRI volume coil for a patient with a deep-brain stimulator under a head imaging exposure are provided as illustrative examples.
On the estimation of the worst-case implant-induced RF-heating in multi-channel MRI
NASA Astrophysics Data System (ADS)
Córcoles, Juan; Zastrow, Earl; Kuster, Niels
2017-06-01
The increasing use of multiple radiofrequency (RF) transmit channels in magnetic resonance imaging (MRI) systems makes it necessary to rigorously assess the risk of RF-induced heating. This risk is especially aggravated with inclusions of medical implants within the body. The worst-case RF-heating scenario is achieved when the local tissue deposition in the at-risk region (generally in the vicinity of the implant electrodes) reaches its maximum value while MRI exposure is compliant with predefined general specific absorption rate (SAR) limits or power requirements. This work first reviews the common approach to estimate the worst-case RF-induced heating in multi-channel MRI environment, based on the maximization of the ratio of two Hermitian forms by solving a generalized eigenvalue problem. It is then shown that the common approach is not rigorous and may lead to an underestimation of the worst-case RF-heating scenario when there is a large number of RF transmit channels and there exist multiple SAR or power constraints to be satisfied. Finally, this work derives a rigorous SAR-based formulation to estimate a preferable worst-case scenario, which is solved by casting a semidefinite programming relaxation of this original non-convex problem, whose solution closely approximates the true worst-case including all SAR constraints. Numerical results for 2, 4, 8, 16, and 32 RF channels in a 3T-MRI volume coil for a patient with a deep-brain stimulator under a head imaging exposure are provided as illustrative examples.
NASA Astrophysics Data System (ADS)
Conway, B. D.
2013-12-01
The Green Valley land subsidence feature is located in southern Arizona, approximately 20 miles south of the Tucson metropolitan area within the town of Sahuarita. Groundwater levels fluctuate as much as 110 feet annually, caused by seasonal pumping demands of a nearby pecan orchard. Recent Arizona Department of Water Resources (ADWR) InSAR data and GNSS survey data reveal that seasonal land subsidence and subsequent uplift are occurring as a direct result of seasonal groundwater level fluctuations. Data from a nearby ADWR transducer shows that the groundwater level begins to decline around middle to late February, dropping as much as 110 feet by the end of June. Groundwater levels generally remain somewhat stable until the middle of October, when the groundwater level begins to rise. Groundwater levels will rise as much as 110 feet by the middle of February; a complete 12-month recovery. ADWR InSAR and GNSS survey data show that land subsidence occurs from February until May followed by a stable period, then uplift occurs from October to February. The Green Valley land subsidence feature is a dynamic hydrogeological system that requires continued deformation monitoring using both InSAR and GNSS data. Radarsat-2 Interferograms that illustrate both seasonal subsidence and uplift. Surveyed elevation and groundwater level change data that document how seasonal groundwater fluctuations result in seasonal land subsidence and uplift.
Validation of Distributed Soil Moisture: Airborne Polarimetric SAR vs. Ground-based Sensor Networks
NASA Astrophysics Data System (ADS)
Jagdhuber, T.; Kohling, M.; Hajnsek, I.; Montzka, C.; Papathanassiou, K. P.
2012-04-01
The knowledge of spatially distributed soil moisture is highly desirable for an enhanced hydrological modeling in terms of flood prevention and for yield optimization in combination with precision farming. Especially in mid-latitudes, the growing agricultural vegetation results in an increasing soil coverage along the crop cycle. For a remote sensing approach, this vegetation influence has to be separated from the soil contribution within the resolution cell to extract the actual soil moisture. Therefore a hybrid decomposition was developed for estimation of soil moisture under vegetation cover using fully polarimetric SAR data. The novel polarimetric decomposition combines a model-based decomposition, separating the volume component from the ground components, with an eigen-based decomposition of the two ground components into a surface and a dihedral scattering contribution. Hence, this hybrid decomposition, which is based on [1,2], establishes an innovative way to retrieve soil moisture under vegetation. The developed inversion algorithm for soil moisture under vegetation cover is applied on fully polarimetric data of the TERENO campaign, conducted in May and June 2011 for the Rur catchment within the Eifel/Lower Rhine Valley Observatory. The fully polarimetric SAR data were acquired in high spatial resolution (range: 1.92m, azimuth: 0.6m) by DLR's novel F-SAR sensor at L-band. The inverted soil moisture product from the airborne SAR data is validated with corresponding distributed ground measurements for a quality assessment of the developed algorithm. The in situ measurements were obtained on the one hand by mobile FDR probes from agricultural fields near the towns of Merzenhausen and Selhausen incorporating different crop types and on the other hand by distributed wireless sensor networks (SoilNet clusters) from a grassland test site (near the town of Rollesbroich) and from a forest stand (within the Wüstebach sub-catchment). Each SoilNet cluster incorporates around 150 wireless measuring devices on a grid of approximately 30ha for distributed soil moisture sensing. Finally, the comparison of both distributed soil moisture products results in a discussion on potentials and limitations for obtaining soil moisture under vegetation cover with high resolution fully polarimetric SAR. [1] S.R. Cloude, Polarisation: applications in remote sensing. Oxford, Oxford University Press, 2010. [2] Jagdhuber, T., Hajnsek, I., Papathanassiou, K.P. and Bronstert, A.: A Hybrid Decomposition for Soil Moisture Estimation under Vegetation Cover Using Polarimetric SAR. Proc. of the 5th International Workshop on Science and Applications of SAR Polarimetry and Polarimetric Interferometry, ESA-ESRIN, Frascati, Italy, January 24-28, 2011, p.1-6.
NASA Astrophysics Data System (ADS)
Zhao, Dezheng; Qu, Chunyan; Shan, Xinjian; Gong, Wenyu; Zhang, Yingfeng; Zhang, Guohong
2018-02-01
On 8 August 2017, a Ms7.0 earthquake stroke the city of Jiuzhaigou, Sichuan, China. The Jiuzhaigou earthquake occurred on a buried fault in the vicinity of three well-known active faults and this event offers a unique opportunity to study tectonic structures in the epicentral region and stress transferring. Here we present coseismic displacement field maps for this earthquake using descending and ascending Sentinel-1A Interferometric Synthetic Aperture Radar (InSAR) data. Deformation covered an area of approximately 50 × 50 km, with a maximum line-of-sight (LOS) displacement of 22 cm in ascending and 14 cm in descending observations on the west side of the source fault. Based on InSAR and Global Positioning System (GPS) measurements, both separately and jointly, we constructed a one-segment model to invert the coseismic slip distribution and dip angle of this event. Our final fault slip model suggests that slip was concentrated at an upper depth of 15 km; there was a maximum slip of 1.3 m and the rupture was dominated by a left-lateral strike-slip motion. The inverted geodetic moment was approximately 6.75 × 1018 Nm, corresponding to a moment magnitude of Mw6.5, consistent with seismological results. The calculated static Coulomb stress changes indicate that most aftershocks occurred in stress increasing zones caused by the mainshock rupture; the Jiuzhaigou earthquake has brought the western part of the Tazang fault 0.1-0.4 MPa closer to failure, indicating an increasing seismic hazard in this region. The Coulomb stress changes caused by the 2008 Mw7.8 Wenchuan earthquake suggest that stress loading from this event acted as a trigger for the Jiuzhaigou earthquake.
ERIC Educational Resources Information Center
Spratley, Ernell; Johnson, Ayah; Sochalski, Julie; Fritz, Marshall; Spencer, William
The characteristics, education, employment patterns, salaries, job satisfaction, and other characteristics of registered nurses (RNs) across the United States were examined in a national survey. Of the initial sample of approximately 54,000 of the nation's more than 3,066,000 licensed RNs, 35,579 RNs (72%) submitted usable responses. From 1980 to…
SAR data for river ice monitoring. How to meet requirements?
NASA Astrophysics Data System (ADS)
Łoś, Helena; Osińska-Skotak, Katarzyna; Pluto-Kossakowska, Joanna
2017-04-01
Although river ice is a natural element of rivers regime it can lead to severe problems such as winter floods or damages of bridges and bank revetments. Services that monitor river ice condition are still often based on field observation. For several year, however, Earth observation data have become of a great interest, especially SAR images, which allows to observe ice and river condition independently of clouds and sunlight. One of requirements of an effective monitoring system is frequent and regular data acquisition. To help to meet this requirement we assessed an impact of selected SAR data parameters into automatic ice types identification. Presented work consists of two parts. The first one focuses on comparison of C-band and X-band data in terms of the main ice type detection. The second part contains an analysis of polarisation reduction from quad-pol to dual-pol data. As the main element of data processing we chose the supervised classification with maximum likelihood algorithm adapted to Wishart distribution. The classification was preceded by statistical analysis of radar signal obtained for selected ice types including separability measures. Two river were selected as areas of interest - the Peace River in Canada and the Vistula in Poland. The results shows that using data registered in both bands similar accuracy of classification into main ice types can be obtain. Differences appear with details e.g. thin initial ice. Classification results obtained from quad-pol and dual-pol data were similar while four classes were selected. With six classes, however, differences between polarisation types have been noticed.
InSAR Monitoring of Surface Deformation in Alberta's Oil Sands
NASA Astrophysics Data System (ADS)
Pearse, J.; Singhroy, V.; Li, J.; Samsonov, S. V.; Shipman, T.; Froese, C. R.
2013-05-01
Alberta's oil sands are among the world's largest deposits of crude oil, and more than 80% of it is too deep to mine, so unconventional in-situ methods are used for extraction. Most in situ extraction techniques, such as Steam-Assisted Gravity Drainage (SAGD), use steam injection to reduce the viscosity of the bitumen, allowing it to flow into wells to be pumped to the surface. As part of the oil sands safety and environmental monitoring program, the energy regulator uses satellite radar to monitor surface deformation associated with in-situ oil extraction. The dense vegetation and sparse infrastructure in the boreal forest of northern Alberta make InSAR monitoring a challenge; however, we have found that surface heave associated with steam injection can be detected using traditional differential InSAR. Infrastructure and installed corner reflectors also allow us to use persistent scatterer methods to obtain time histories of deformation at individual sites. We have collected and processed several tracks of RADARSAT-2 data over a broad area of the oil sands, and have detected surface deformation signals of approximately 2-3 cm per year, with time series that correlate strongly with monthly SAGD steam injection volumes.
Tomographic Imaging of a Forested Area By Airborne Multi-Baseline P-Band SAR.
Frey, Othmar; Morsdorf, Felix; Meier, Erich
2008-09-24
In recent years, various attempts have been undertaken to obtain information about the structure of forested areas from multi-baseline synthetic aperture radar data. Tomographic processing of such data has been demonstrated for airborne L-band data but the quality of the focused tomographic images is limited by several factors. In particular, the common Fourierbased focusing methods are susceptible to irregular and sparse sampling, two problems, that are unavoidable in case of multi-pass, multi-baseline SAR data acquired by an airborne system. In this paper, a tomographic focusing method based on the time-domain back-projection algorithm is proposed, which maintains the geometric relationship between the original sensor positions and the imaged target and is therefore able to cope with irregular sampling without introducing any approximations with respect to the geometry. The tomographic focusing quality is assessed by analysing the impulse response of simulated point targets and an in-scene corner reflector. And, in particular, several tomographic slices of a volume representing a forested area are given. The respective P-band tomographic data set consisting of eleven flight tracks has been acquired by the airborne E-SAR sensor of the German Aerospace Center (DLR).
Lee, Hyun; Mittal, Anuradha; Patel, Kavankumar; Gatuz, Joseph L; Truong, Lena; Torres, Jaime; Mulhearn, Debbie C; Johnson, Michael E
2014-01-01
We have used a combination of virtual screening (VS) and high-throughput screening (HTS) techniques to identify novel, non-peptidic small molecule inhibitors against human SARS-CoV 3CLpro. A structure-based VS approach integrating docking and pharmacophore based methods was employed to computationally screen 621,000 compounds from the ZINC library. The screening protocol was validated using known 3CLpro inhibitors and was optimized for speed, improved selectivity, and for accommodating receptor flexibility. Subsequently, a fluorescence-based enzymatic HTS assay was developed and optimized to experimentally screen approximately 41,000 compounds from four structurally diverse libraries chosen mainly based on the VS results. False positives from initial HTS hits were eliminated by a secondary orthogonal binding analysis using surface plasmon resonance (SPR). The campaign identified a reversible small molecule inhibitor exhibiting mixed-type inhibition with a K(i) value of 11.1 μM. Together, these results validate our protocols as suitable approaches to screen virtual and chemical libraries, and the newly identified compound reported in our study represents a promising structural scaffold to pursue for further SARS-CoV 3CLpro inhibitor development. Copyright © 2013. Published by Elsevier Ltd.
Vasco, D. W.; Rutqvist, Jonny; Ferretti, Alessandro; ...
2013-06-07
In this study, we resolve deformation at The Geysers Geothermal Field using two distinct sets of interferometric synthetic aperture radar (InSAR) data. The first set of observations utilize archived European Space Agency C-band synthetic aperture radar data from 1992 through 1999 to image the long-term and large-scale subsidence at The Geysers. The peak range velocity of approximately 50 mm/year agrees with previous estimates from leveling and global positioning system observations. Data from a second set of measurements, acquired by TerraSAR-X satellites, extend from May 2011 until April 2012 and overlap the C-band data spatially but not temporally. These X-band data,more » analyzed using a combined permanent and distributed scatterer algorithm, provide a higher density of scatterers (1122 per square kilometer) than do the C-band data (12 per square kilometer). The TerraSAR-X observations resolve 1 to 2 cm of deformation due to water injection into a Northwest Geysers enhanced geothermal system well, initiated on October 2011. Lastly, the temporal variation of the deformation is compatible with estimates from coupled numerical modeling.« less
YSAR: a compact low-cost synthetic aperture radar
NASA Astrophysics Data System (ADS)
Thompson, Douglas G.; Arnold, David V.; Long, David G.; Miner, Gayle F.; Karlinsey, Thomas W.; Robertson, Adam E.
1997-09-01
The Brigham Young University Synthetic Aperture Radar (YSAR) is a compact, inexpensive SAR system which can be flown on a small aircraft. The system has exhibited a resolution of approximately 0.8 m by 0.8 m in test flights in calm conditions. YSAR has been used to collect data over archeological sites in Israel. Using a relatively low frequency (2.1 GHz), we hope to be able to identify walls or other archeological features to assist in excavation. A large data set of radar and photographic data have been collected over sites at Tel Safi, Qumran, Tel Micnah, and the Zippori National Forest in Israel. We show sample images from the archeological data. We are currently working on improved autofocus algorithms for this data and are developing a small, low-cost interferometric SAR system (YINSAR) for operation from a small aircraft.
Modeling of SAR returns from a red pine stand
NASA Technical Reports Server (NTRS)
Lang, R. H.; Kilic, O.; Chauhan, N. S.; Ranson, J.
1992-01-01
Bright P-band radar returns from red pine forests have been observed on synthetic aperture radar (SAR) images in Bangor, Maine. A plot of red pine trees was selected for the characterization and modeling to understand the cause of the high P-band returns. The red pine stand under study consisted of mature trees. Diameter at breast height (DBH) measurements were made to determine stand density as a function of tree diameter. Soil moisture and bulk density measurements were taken along with ground rough surface profiles. Detailed biomass measurements of the needles, shoots, branches, and trunks were also taken. These site statistics have been used in a distorted Born approximation model of the forest. Computations indicate that the direct-reflected or the double-bounce contributions from the ground are responsible for the high observed P-band returns for HH polarization.
Satellite radar interferometry measures deformation at Okmok Volcano
Lu, Zhong; Mann, Dorte; Freymueller, Jeff
1998-01-01
The center of the Okmok caldera in Alaska subsided 140 cm as a result of its February– April 1997 eruption, according to satellite data from ERS-1 and ERS-2 synthetic aperture radar (SAR) interferometry. The inferred deflationary source was located 2.7 km beneath the approximate center of the caldera using a point source deflation model. Researchers believe this source is a magma chamber about 5 km from the eruptive source vent. During the 3 years before the eruption, the center of the caldera uplifted by about 23 cm, which researchers believe was a pre-emptive inflation of the magma chamber. Scientists say such measurements demonstrate that radar interferometry is a promising spaceborne technique for monitoring remote volcanoes. Frequent, routine acquisition of images with SAR interferometry could make near realtime monitoring at such volcanoes the rule, aiding in eruption forecasting.
Slip-rate measurements on the Karakorum Fault may imply secular variations in fault motion.
Chevalier, M-L; Ryerson, F J; Tapponnier, P; Finkel, R C; Van Der Woerd, J; Haibing, Li; Qing, Liu
2005-01-21
Beryllium-10 surface exposure dating of offset moraines on one branch of the Karakorum Fault west of the Gar basin yields a long-term (140- to 20-thousand-year) right-lateral slip rate of approximately 10.7 +/- 0.7 millimeters per year. This rate is 10 times larger than that inferred from recent InSAR analyses ( approximately 1 +/- 3 millimeters per year) that span approximately 8 years and sample all branches of the fault. The difference in slip-rate determinations suggests that large rate fluctuations may exist over centennial or millennial time scales. Such fluctuations would be consistent with mechanical coupling between the seismogenic, brittle-creep, and ductile shear sections of faults that reach deep into the crust.
ERIC Educational Resources Information Center
Pooyan, Abdullah; And Others
Turnover rates for nurses are among the highest for all professional employees. This study investigated the potential predictors of registered nurses' intention to quit. Survey questionnaires were mailed to a population of 779 registered nurses from two hospitals in North Dakota. Approximately 4 weeks later, usable responses were received from 353…
Analysis of Ground Displacements in Taipei Area by Using High Resolution X-band SAR Interferometry
NASA Astrophysics Data System (ADS)
Tung, H.; Chen, H. Y.; Hu, J. C.
2014-12-01
Located at the northern part of Taiwan, Taipei is the most densely populated city and the center of politic, economic, and culture of this island. North of the Taipei basin, the active Tatun volcano group with the eruptive potential to devastate the entire Taipei is only 15 km away from the capital Taipei. Furthermore, the active Shanchiao fault located in the western margin of Taipei basin. Therefore, it is not only an interesting scientific topic but also a strong social impact to better understand the assessment and mitigation of geological hazard in the metropolitan Taipei city. In this study, we use 12 high resolution X-band SAR images from the new generation COSMO-SkyMed (CSK) constellation for associating with leveling and GPS data to monitor surface deformation around the Shanchiao fault and the Tatun volcano group. The stripmap mode of CSK SAR images provides spatial resolution of 3 m x 3 m, which is one order of magnitude better than the previous available satellite SAR data. Furthermore, the more frequent revisit of the same Area of Interest (AOI) of the present X-band missions provides massive datasets to avoid the baseline limitation and temporal decorrelation to improve the temporal resolution of deformation in time series. After transferring the GPS vectors and leveling data to the LOS direction by referring to continuous GPS station BANC, the R square between PS velocities and GPS velocities is approximate to 0.9, which indicates the high reliability of our PSInSAR result. In addition, the well-fitting profiles between leveling data and PSInSAR result along two leveling routes both demonstrate that the significant deformation gradient mainly occurs along the Shanchiao fault. The severe land subsidence area is located in the western part of Taipei basin just next to the Shanchiao fault with a maximum of SRD rate of 30 mm/yr. However, the severe subsidence area, Wuku, is also one industrial area in Taipei which could be attributed to anthropogenic effect. In the future, we will use all available images to monitor the temporal and spatial variation in deformation to better understand the activity of the Shanchiao fault.
Enhancing the Accessibility and Utility of UAVSAR L-band SAR Data
NASA Astrophysics Data System (ADS)
Atwood, D.; Arko, S. A.; Gens, R.; Sanches, R. R.
2011-12-01
The UAVSAR instrument, developed at NASA Jet Propulsion Lab, is a reconfigurable L-band, quad-polarimetric Synthetic Aperture Radar (SAR) developed specifically for repeat-track differential interferometry (InSAR). It offers resolution of approximately 5m and swaths greater than 16 km. Although designed to be flown aboard a UAV (Uninhabited Aerial Vehicle), it is currently being flown aboard a Gulfstream III in an ambitious set of campaigns around the world. The current archive from 2009 contains data from more than 100 missions from North America, Central America, the Caribbean, and Greenland. Compared with most SAR data from satellites, UAVSAR offers higher resolution, full-polarimetry, and an impressive noise floor. For scientists, these datasets present wonderful opportunities for understanding Earth processes and developing new algorithms for information extraction. Yet despite the diverse range of coverage, UAVSAR is still relatively under-utilized. In its capacity as the NASA SAR DAAC, the Alaska Satellite Facility (ASF) is interested in expanding recognition of this data and serving data products that can be readily downloaded into a Geographic Information System (GIS) environment. Two hurdles exist: one is the large size of the data products and the second is the format of the data. The data volumes are in excess of several GB; presenting slow downloads and overwhelming many software programs. Secondly, while the data is appropriately formatted for expert users, it may prove challenging for scientists who have not previously worked with SAR. This paper will address ways that ASF is working to reduce data volume while maintaining the integrity of the data. At the same time, the creation of value-added products that permit immediate visualization in a GIS environment will be described. Conversion of the UAVSAR polarimetric data to radiometrically terrain-corrected Pauli images in a GeoTIFF format will permit researchers to understand the scattering mechanisms that characterize various land cover classes in their study areas. Specific examples of UAVSAR polarimetric classifications will be used to demonstrate the benefit of the UAVSAR products for Earth science projects.
Monitoring a boreal wildfire using multi-temporal Radarsat-1 intensity and coherence images
Rykhus, Russell P.; Lu, Zhong
2011-01-01
Twenty-five C-band Radarsat-1 synthetic aperture radar (SAR) images acquired from the summer of 2002 to the summer of 2005 are used to map a 2003 boreal wildfire (B346) in the Yukon Flats National Wildlife Refuge, Alaska under conditions of near-persistent cloud cover. Our analysis is primarily based on the 15 SAR scenes acquired during arctic growing seasons. The Radarsat-1 intensity data are used to map the onset and progression of the fire, and interferometric coherence images are used to qualify burn severity and monitor post-fire recovery. We base our analysis of the fire on three test sites, two from within the fire and one unburned site. The B346 fire increased backscattered intensity values for the two burn study sites by approximately 5–6 dB and substantially reduced coherence from background levels of approximately 0.8 in unburned background forested areas to approximately 0.2 in the burned area. Using ancillary vegetation information from the National Land Cover Database (NLCD) and information on burn severity from Normalized Burn Ratio (NBR) data, we conclude that burn site 2 was more severely burned than burn site 1 and that C-band interferometric coherence data are useful for mapping landscape changes due to fire. Differences in burn severity and topography are determined to be the likely reasons for the observed differences in post-fire intensity and coherence trends between burn sites.
Space Radar Image of Kliuchevskoi, Russia
NASA Technical Reports Server (NTRS)
1994-01-01
This is an X-band seasonal image of the Maly Semlyachik volcano, which is part of the Karymsky volcano group on Kamchatka peninsula, Russia. The image is centered at 54.2 degrees north latitude and 159.6 degrees east longitude. This image was acquired by the Spaceborne Imaging Radar-C and X-band Synthetic Aperture Radar (SIR-C/X-SAR) aboard the space shuttle Endeavour on April 9, 1994, during the first flight of the radar system, and on September 30, 1994, during the second flight. The image channels have been assigned the following colors: red corresponds to data acquired on April 9; green corresponds to data acquired on September 30; and blue corresponds to the ratio between data from April 9 and September 30, 1994. Kamchatka is twice as large as England, Scotland and Wales combined and is home to approximately 470,000 residents. The region is characterized by a chain of volcanoes stretching 800 kilometers (500 miles) across the countryside. Many of the volcanoes, including the active Maly Semlyachik volcano in this image, have erupted during this century. But the most active period in creating the three characteristic craters of this volcano goes back 20,000, 12,000 and 2,000 years ago. The highest summit of the oldest crater reaches about 1,560 meters (1,650 feet). The radar images reveal the geological structures of craters and lava flows in order to improve scientists' knowledge of these sometimes vigorously active volcanoes. This seasonal composite also highlights the ecological differences that have occurred between April and October 1994. In April the whole area was snow-covered and, at the coast, an ice sheet extended approximately 5 kilometers (3 miles) into the sea. The area shown surrounding the volcano is covered by low vegetation much like scrub. Kamchatka also has extensive forests, which belong to the northern frontier of Taiga, the boreal forest ecosystem. This region plays an important role in the world's carbon cycle. Trees require 60 years to mature in Kamchatka's 120-day growing season. The forest industry is managing these forests and practicing selective cutting to allow younger trees time to grow and reseed. X-SAR images will aid in mapping these deforested areas and in encouraging further recultivation efforts. Spaceborne Imaging Radar-C and X-band Synthetic Aperture Radar (SIR-C/X-SAR) is part of NASA's Mission to Planet Earth. The radars illuminate Earth with microwaves, allowing detailed observations at any time, regardless of weather or sunlight conditions. SIR-C/X-SAR uses three microwave wavelengths: L-band (24 cm), C-band (6 cm) and X-band (3 cm). The multi-frequency data will be used by the international scientific community to better understand the global environment and how it is changing. The SIR-C/X-SAR data, complemented by aircraft and ground studies, will give scientists clearer insights into those environmental changes which are caused by nature and those changes which are induced by human activity. SIR-C was developed by NASA's Jet Propulsion Laboratory. X-SAR was developed by the Dornier and Alenia Spazio companies for the German space agency, Deutsche Agentur fuer Raumfahrtange-legenheiten (DARA), and the Italian space agency, Agenzia Spaziale Italiana (ASI), with the Deutsche Forschungsanstalt fuer Luft und Raumfahrt e.V.(DLR), the major partner in science, operations and data processing of X-SAR.
Lau, Susanna K. P.; Feng, Yun; Chen, Honglin; Luk, Hayes K. H.; Yang, Wei-Hong; Li, Kenneth S. M.; Zhang, Yu-Zhen; Huang, Yi; Song, Zhi-Zhong; Chow, Wang-Ngai; Fan, Rachel Y. Y.; Ahmed, Syed Shakeel; Yeung, Hazel C.; Lam, Carol S. F.; Cai, Jian-Piao; Wong, Samson S. Y.; Chan, Jasper F. W.; Yuen, Kwok-Yung
2015-01-01
ABSTRACT Despite the identification of horseshoe bats as the reservoir of severe acute respiratory syndrome (SARS)-related coronaviruses (SARSr-CoVs), the origin of SARS-CoV ORF8, which contains the 29-nucleotide signature deletion among human strains, remains obscure. Although two SARS-related Rhinolophus sinicus bat CoVs (SARSr-Rs-BatCoVs) previously detected in Chinese horseshoe bats (Rhinolophus sinicus) in Yunnan, RsSHC014 and Rs3367, possessed 95% genome identities to human and civet SARSr-CoVs, their ORF8 protein exhibited only 32.2 to 33% amino acid identities to that of human/civet SARSr-CoVs. To elucidate the origin of SARS-CoV ORF8, we sampled 348 bats of various species in Yunnan, among which diverse alphacoronaviruses and betacoronaviruses, including potentially novel CoVs, were identified, with some showing potential interspecies transmission. The genomes of two betacoronaviruses, SARSr-Rf-BatCoV YNLF_31C and YNLF_34C, from greater horseshoe bats (Rhinolophus ferrumequinum), possessed 93% nucleotide identities to human/civet SARSr-CoV genomes. Although these two betacoronaviruses displayed lower similarities than SARSr-Rs-BatCoV RsSHC014 and Rs3367 in S protein to civet SARSr-CoVs, their ORF8 proteins demonstrated exceptionally high (80.4 to 81.3%) amino acid identities to that of human/civet SARSr-CoVs, compared to SARSr-BatCoVs from other horseshoe bats (23.2 to 37.3%). Potential recombination events were identified around ORF8 between SARSr-Rf-BatCoVs and SARSr-Rs-BatCoVs, leading to the generation of civet SARSr-CoVs. The expression of ORF8 subgenomic mRNA suggested that the ORF8 protein may be functional in SARSr-Rf-BatCoVs. The high Ka/Ks ratio among human SARS-CoVs compared to that among SARSr-BatCoVs supported that ORF8 is under strong positive selection during animal-to-human transmission. Molecular clock analysis using ORF1ab showed that SARSr-Rf-BatCoV YNLF_31C and YNLF_34C diverged from civet/human SARSr-CoVs in approximately 1990. SARS-CoV ORF8 originated from SARSr-CoVs of greater horseshoe bats through recombination, which may be important for animal-to-human transmission. IMPORTANCE Although horseshoe bats are the primary reservoir of SARS-related coronaviruses (SARSr-CoVs), it is still unclear how these bat viruses have evolved to cross the species barrier to infect civets and humans. Most human SARS-CoV epidemic strains contain a signature 29-nucleotide deletion in ORF8, compared to civet SARSr-CoVs, suggesting that ORF8 may be important for interspecies transmission. However, the origin of SARS-CoV ORF8 remains obscure. In particular, SARSr-Rs-BatCoVs from Chinese horseshoe bats (Rhinolophus sinicus) exhibited <40% amino acid identities to human/civet SARS-CoV in the ORF8 protein. We detected diverse alphacoronaviruses and betacoronaviruses among various bat species in Yunnan, China, including two SARSr-Rf-BatCoVs from greater horseshoe bats that possessed ORF8 proteins with exceptionally high amino acid identities to that of human/civet SARSr-CoVs. We demonstrated recombination events around ORF8 between SARSr-Rf-BatCoVs and SARSr-Rs-BatCoVs, leading to the generation of civet SARSr-CoVs. Our findings offer insight into the evolutionary origin of SARS-CoV ORF8 protein, which was likely acquired from SARSr-CoVs of greater horseshoe bats through recombination. PMID:26269185
Lau, Susanna K P; Feng, Yun; Chen, Honglin; Luk, Hayes K H; Yang, Wei-Hong; Li, Kenneth S M; Zhang, Yu-Zhen; Huang, Yi; Song, Zhi-Zhong; Chow, Wang-Ngai; Fan, Rachel Y Y; Ahmed, Syed Shakeel; Yeung, Hazel C; Lam, Carol S F; Cai, Jian-Piao; Wong, Samson S Y; Chan, Jasper F W; Yuen, Kwok-Yung; Zhang, Hai-Lin; Woo, Patrick C Y
2015-10-01
Despite the identification of horseshoe bats as the reservoir of severe acute respiratory syndrome (SARS)-related coronaviruses (SARSr-CoVs), the origin of SARS-CoV ORF8, which contains the 29-nucleotide signature deletion among human strains, remains obscure. Although two SARS-related Rhinolophus sinicus bat CoVs (SARSr-Rs-BatCoVs) previously detected in Chinese horseshoe bats (Rhinolophus sinicus) in Yunnan, RsSHC014 and Rs3367, possessed 95% genome identities to human and civet SARSr-CoVs, their ORF8 protein exhibited only 32.2 to 33% amino acid identities to that of human/civet SARSr-CoVs. To elucidate the origin of SARS-CoV ORF8, we sampled 348 bats of various species in Yunnan, among which diverse alphacoronaviruses and betacoronaviruses, including potentially novel CoVs, were identified, with some showing potential interspecies transmission. The genomes of two betacoronaviruses, SARSr-Rf-BatCoV YNLF_31C and YNLF_34C, from greater horseshoe bats (Rhinolophus ferrumequinum), possessed 93% nucleotide identities to human/civet SARSr-CoV genomes. Although these two betacoronaviruses displayed lower similarities than SARSr-Rs-BatCoV RsSHC014 and Rs3367 in S protein to civet SARSr-CoVs, their ORF8 proteins demonstrated exceptionally high (80.4 to 81.3%) amino acid identities to that of human/civet SARSr-CoVs, compared to SARSr-BatCoVs from other horseshoe bats (23.2 to 37.3%). Potential recombination events were identified around ORF8 between SARSr-Rf-BatCoVs and SARSr-Rs-BatCoVs, leading to the generation of civet SARSr-CoVs. The expression of ORF8 subgenomic mRNA suggested that the ORF8 protein may be functional in SARSr-Rf-BatCoVs. The high Ka/Ks ratio among human SARS-CoVs compared to that among SARSr-BatCoVs supported that ORF8 is under strong positive selection during animal-to-human transmission. Molecular clock analysis using ORF1ab showed that SARSr-Rf-BatCoV YNLF_31C and YNLF_34C diverged from civet/human SARSr-CoVs in approximately 1990. SARS-CoV ORF8 originated from SARSr-CoVs of greater horseshoe bats through recombination, which may be important for animal-to-human transmission. Although horseshoe bats are the primary reservoir of SARS-related coronaviruses (SARSr-CoVs), it is still unclear how these bat viruses have evolved to cross the species barrier to infect civets and humans. Most human SARS-CoV epidemic strains contain a signature 29-nucleotide deletion in ORF8, compared to civet SARSr-CoVs, suggesting that ORF8 may be important for interspecies transmission. However, the origin of SARS-CoV ORF8 remains obscure. In particular, SARSr-Rs-BatCoVs from Chinese horseshoe bats (Rhinolophus sinicus) exhibited <40% amino acid identities to human/civet SARS-CoV in the ORF8 protein. We detected diverse alphacoronaviruses and betacoronaviruses among various bat species in Yunnan, China, including two SARSr-Rf-BatCoVs from greater horseshoe bats that possessed ORF8 proteins with exceptionally high amino acid identities to that of human/civet SARSr-CoVs. We demonstrated recombination events around ORF8 between SARSr-Rf-BatCoVs and SARSr-Rs-BatCoVs, leading to the generation of civet SARSr-CoVs. Our findings offer insight into the evolutionary origin of SARS-CoV ORF8 protein, which was likely acquired from SARSr-CoVs of greater horseshoe bats through recombination. Copyright © 2015, American Society for Microbiology. All Rights Reserved.
Mutational dynamics of the SARS coronavirus in cell culture and human populations isolated in 2003
Vega, Vinsensius B; Ruan, Yijun; Liu, Jianjun; Lee, Wah Heng; Wei, Chia Lin; Se-Thoe, Su Yun; Tang, Kin Fai; Zhang, Tao; Kolatkar, Prasanna R; Ooi, Eng Eong; Ling, Ai Ee; Stanton, Lawrence W; Long, Philip M; Liu, Edison T
2004-01-01
Background The SARS coronavirus is the etiologic agent for the epidemic of the Severe Acute Respiratory Syndrome. The recent emergence of this new pathogen, the careful tracing of its transmission patterns, and the ability to propagate in culture allows the exploration of the mutational dynamics of the SARS-CoV in human populations. Methods We sequenced complete SARS-CoV genomes taken from primary human tissues (SIN3408, SIN3725V, SIN3765V), cultured isolates (SIN848, SIN846, SIN842, SIN845, SIN847, SIN849, SIN850, SIN852, SIN3408L), and five consecutive Vero cell passages (SIN2774_P1, SIN2774_P2, SIN2774_P3, SIN2774_P4, SIN2774_P5) arising from SIN2774 isolate. These represented individual patient samples, serial in vitro passages in cell culture, and paired human and cell culture isolates. Employing a refined mutation filtering scheme and constant mutation rate model, the mutation rates were estimated and the possible date of emergence was calculated. Phylogenetic analysis was used to uncover molecular relationships between the isolates. Results Close examination of whole genome sequence of 54 SARS-CoV isolates identified before 14th October 2003, including 22 from patients in Singapore, revealed the mutations engendered during human-to-Vero and Vero-to-human transmission as well as in multiple Vero cell passages in order to refine our analysis of human-to-human transmission. Though co-infection by different quasipecies in individual tissue samples is observed, the in vitro mutation rate of the SARS-CoV in Vero cell passage is negligible. The in vivo mutation rate, however, is consistent with estimates of other RNA viruses at approximately 5.7 × 10-6 nucleotide substitutions per site per day (0.17 mutations per genome per day), or two mutations per human passage (adjusted R-square = 0.4014). Using the immediate Hotel M contact isolates as roots, we observed that the SARS epidemic has generated four major genetic groups that are geographically associated: two Singapore isolates, one Taiwan isolate, and one North China isolate which appears most closely related to the putative SARS-CoV isolated from a palm civet. Non-synonymous mutations are centered in non-essential ORFs especially in structural and antigenic genes such as the S and M proteins, but these mutations did not distinguish the geographical groupings. However, no non-synonymous mutations were found in the 3CLpro and the polymerase genes. Conclusions Our results show that the SARS-CoV is well adapted to growth in culture and did not appear to undergo specific selection in human populations. We further assessed that the putative origin of the SARS epidemic was in late October 2002 which is consistent with a recent estimate using cases from China. The greater sequence divergence in the structural and antigenic proteins and consistent deletions in the 3' – most portion of the viral genome suggest that certain selection pressures are interacting with the functional nature of these validated and putative ORFs. PMID:15347429
Review: Endogenously Produced Volatiles for In Vitro Toxicity Testing Using Cell Lines
Due to the approximately 86,000 chemicals registered under the Toxic Substances Control Act and increasing ethical concerns regarding animal testing, it is not economically or technically feasible to screen every registered chemical for toxicity using animal-based toxicity assays...
Sunohara, Tetsu; Hirata, Akimasa; Laakso, Ilkka; Onishi, Teruo
2014-07-21
This study investigates the specific absorption rate (SAR) and the in situ electric field in anatomically based human models for the magnetic field from an inductive wireless power transfer system developed on the basis of the specifications of the wireless power consortium. The transfer system consists of two induction coils covered by magnetic sheets. Both the waiting and charging conditions are considered. The transfer frequency considered in this study is 140 kHz, which is within the range where the magneto-quasi-static approximation is valid. The SAR and in situ electric field in the chest and arm of the models are calculated by numerically solving the scalar potential finite difference equation. The electromagnetic modelling of the coils in the wireless power transfer system is verified by comparing the computed and measured magnetic field distributions. The results indicate that the peak value of the SAR averaged over a 10 g of tissue and that of the in situ electric field are 72 nW kg(-1) and 91 mV m(-1) for a transmitted power of 1 W, Consequently, the maximum allowable transmitted powers satisfying the exposure limits of the SAR (2 W kg(-1)) and the in situ electric field (18.9 V m(-1)) are found to be 28 MW and 43 kW. The computational results show that the in situ electric field in the chest is the most restrictive factor when compliance with the wireless power transfer system is evaluated according to international guidelines.
Tropical forest plantation biomass estimation using RADARSAT-SAR and TM data of south china
NASA Astrophysics Data System (ADS)
Wang, Chenli; Niu, Zheng; Gu, Xiaoping; Guo, Zhixing; Cong, Pifu
2005-10-01
Forest biomass is one of the most important parameters for global carbon stock model yet can only be estimated with great uncertainties. Remote sensing, especially SAR data can offers the possibility of providing relatively accurate forest biomass estimations at a lower cost than inventory in study tropical forest. The goal of this research was to compare the sensitivity of forest biomass to Landsat TM and RADARSAT-SAR data and to assess the efficiency of NDVI, EVI and other vegetation indices in study forest biomass based on the field survey date and GIS in south china. Based on vegetation indices and factor analysis, multiple regression and neural networks were developed for biomass estimation for each species of the plantation. For each species, the better relationships between the biomass predicted and that measured from field survey was obtained with a neural network developed for the species. The relationship between predicted and measured biomass derived from vegetation indices differed between species. This study concludes that single band and many vegetation indices are weakly correlated with selected forest biomass. RADARSAT-SAR Backscatter coefficient has a relatively good logarithmic correlation with forest biomass, but neither TM spectral bands nor vegetation indices alone are sufficient to establish an efficient model for biomass estimation due to the saturation of bands and vegetation indices, multiple regression models that consist of spectral and environment variables improve biomass estimation performance. Comparing with TM, a relatively well estimation result can be achieved by RADARSAT-SAR, but all had limitations in tropical forest biomass estimation. The estimation results obtained are not accurate enough for forest management purposes at the forest stand level. However, the approximate volume estimates derived by the method can be useful in areas where no other forest information is available. Therefore, this paper provides a better understanding of relationships of remote sensing data and forest stand parameters used in forest parameter estimation models.
Attenuation of Selected Emerging Contaminants During River Transport
NASA Astrophysics Data System (ADS)
Reinhard, M.; Gross, B.; Hadeler, A.
2002-12-01
The ubiquitous occurrence of emerging (non-regulated) contaminants in the aquatic environment is of concern because some of these chemicals are biologically active at low concentrations and a potential threat to wildlife and human health.. Emerging contaminants include a diverse range of chemicals, including pharmaceuticals, natural and synthetic hormones and industrial surfactants, such as alkylphenol ethoxylates (APEO) and their metabolites. To address the ecotoxicological impact of these chemicals, it is necessary to know their sources, removal efficiencies during wastewater treatment, and their behavior in the environment. In this study, the fate of selected emerging contaminants in the Santa Ana River (SAR) in Southern California was investigated. The SAR originates in the San Bernardino Mountains and flows 80 miles into the Pacific Ocean. The SAR flow stems mainly from storm runoff, wastewater treatment effluents and several other minor sources. During the dry season, SAR flow is dominated by effluent from public wastewater treatment plants. Input into the SAR was studied by analyzing samples from four major treatment plants that employ different tertiary treatment processes. To assess the fate during river water transport and during wetland treatment, samples from six sites along the river were analyzed. Effluent samples were analyzed every two months, river water every four months. River samples were taken considering the flow velocity, which is approximately 1 mile per hour. The analytical method involves solid-phase extraction using C-18 cartridges and extraction of three fractions. Samples were analyzed with and without further derivatization using GC/MS and GC/MS/MS. Results indicate significant contaminant removal during river transport, presumably by photochemical oxidation. Within a distance of nine miles, pharmaceuticals, plasticizers, flame retardants, APEOs and metabolites were attenuated with removal rates ranging from 76% for a flame retardant to up to 97% for some APEO metabolites. The two pharmaceuticals gemfibrozil and ibuprofen were attenuated by more than 90%. Whether photochemical transformations are mainly responsible for the observed removals remains to be investigated.
NASA Astrophysics Data System (ADS)
Liu, L.; Jiang, L.; Sun, Y.; Wang, H.
2014-12-01
Surge-type glaciers are very important to understanding of glacier dynamics and mass balance. They generally experience well-defined cyclical non-steady flow, with alternation between short active phases (months to years) and a longer quiescent phase (years to decades). Previous studies reported that most of surge-type glaciers in the High Asian Mountain were detected in the Himalayas and Karakoram, however, few studies were carried out in the central Tibetan Plateau (TP). This study is focused on identification and characteristics of surge-type glaciers by using satellite InSAR technique on the Puruogangri Ice Field (PIF) in the central TP, the largest modern ice field over the TP. Firstly, a very high-resolution DEM was retrieved by applying bi-static InSAR to a pair of TerraSAR-X/Tandem-X data in 2012, then elevation changes were estimated by subtracting SRTM-X DEM (2000) from it. Secondly, bi-temporal surface velocities were measured by D-InSAR technique with a pair of ERS tandem data in 1996 and a pair of ALOS PALSAR data in 2009. The preliminary results of elevation changes show that a significant thickness increase of approximate 70 meters was detected at terminus of the glacier (WGMS id: 5Z213E0012) between 2000 and 2012. In particular, an analysis of glacier elevation changes with altitude exhibits that this glacier experienced a surging before 2012. Moreover, the results of surface velocity demonstrate that the ice-flow velocity amplitude of this glacier was relatively slow with average values of about 3.5 m/yr in 1996 and 3.0 m/yr in 2009. A synergistic analysis of the changes in elevation and velocity infers that the glacier surge event might occur between 1996 and 2009. But at the present we could not make sure of its exactly active and quiescent phase, and further studies are required.
Soil conservation applications with C-band SAR
NASA Technical Reports Server (NTRS)
Brisco, B.; Brown, R. J.; Naunheimer, J.; Bedard, D.
1992-01-01
Soil conservation programs are becoming more important as the growing human population exerts greater pressure on this non-renewable resource. Indeed, soil degradation affects approximately 10 percent of Canada's agricultural land with an estimated loss of 6,000 hectares of topsoil annually from Ontario farmland alone. Soil loss not only affects agricultural productivity but also decreases water quality and can lead to siltation problems. Thus, there is a growing demand for soil conservation programs and a need to develop an effective monitoring system. Topography and soil type information can easily be handled within a geographic information system (GIS). Information about vegetative cover type and surface roughness, which both experience considerable temporal change, can be obtained from remote sensing techniques. For further development of the technology to produce an operational soil conservation monitoring system, an experiment was conducted in Oxford County, Ontario which investigated the separability of fall surface cover type using C-band Synthetic Aperture Radar (SAR) data.
Auroral LSTIDs and SAR Arc Occurrences in Northern California During Geomagnetic Storms
NASA Astrophysics Data System (ADS)
Bhatt, A.; Kendall, E. A.
2015-12-01
A 630nm allsky imager has been operated for two years in northern California at the Hat Creek Radio Observatory. F-region airglow data captured by the imager ranges from approximately L=1.7 -2.7. Since installation of the imager several geomagnetic storms have occurred with varying intensities. Two main manifestations of the geomagnetic storms are observed in the 630 nm airglow data: large-scale traveling ionospheric disturbances that are launched from the auroral zone and Stable Auroral Red (SAR) arcs during more intense geomagnetic storms. We will present a statistical analysis of these storm-time phenomena in northern California for the past eighteen months. This imager is part of a larger all-sky imaging network across the continental United States, termed MANGO (Midlatitude All-sky-imaging Network for Geophysical Observations). Where available, we will add data from networked imagers located at similar L-shell in other states as well.
Healthy life expectancy in Hong Kong Special Administrative Region of China.
Law, C. K.; Yip, P. S. F.
2003-01-01
Sullivan's method and a regression model were used to calculate healthy life expectancy (HALE) for men and women in Hong Kong Special Administrative Region (Hong Kong SAR) of China. These methods need estimates of the prevalence and information on disability distributions of 109 diseases and HALE for 191 countries by age, sex and region of the world from the WHO's health assessment of 2000. The population of Hong Kong SAR has one of the highest healthy life expectancies in the world. Sullivan's method gives higher estimates than the classic linear regression method. Although Sullivan's method accurately calculates the influence of disease prevalence within small areas and regions, the regression method can approximate HALE for all economies for which information on life expectancy is available. This paper identifies some problems of the two methods and discusses the accuracy of estimates of HALE that rely on data from the WHO assessment. PMID:12640475
Multisensor comparison of ice concentration estimates in the marginal ice zone
NASA Technical Reports Server (NTRS)
Burns, B. A.; Cavalieri, D. J.; Gloersen, P.; Keller, M. R.; Campbell, W. J.
1987-01-01
Aircraft remote sensing data collected during the 1984 summer Marginal Ice Zone Experiment in the Fram Strait are used to compare ice concentration estimates derived from synthetic aperture radar (SAR) imagery, passive microwave imagery at several frequencies, aerial photography, and spectral photometer data. The comparison is carried out not only to evaluate SAR performance against more established techniques but also to investigate how ice surface conditions, imaging geometry, and choice of algorithm parameters affect estimates made by each sensor.Active and passive microwave sensor estimates of ice concentration derived using similar algorithms show an rms difference of 13 percent. Agreement between each microwave sensor and near-simultaneous aerial photography is approximately the same (14 percent). The availability of high-resolution microwave imagery makes it possible to ascribe the discrepancies in the concentration estimates to variations in ice surface signatures in the scene.
NASA Astrophysics Data System (ADS)
Walker, David M.; Allingham, David; Lee, Heung Wing Joseph; Small, Michael
2010-02-01
Small world network models have been effective in capturing the variable behaviour of reported case data of the SARS coronavirus outbreak in Hong Kong during 2003. Simulations of these models have previously been realized using informed “guesses” of the proposed model parameters and tested for consistency with the reported data by surrogate analysis. In this paper we attempt to provide statistically rigorous parameter distributions using Approximate Bayesian Computation sampling methods. We find that such sampling schemes are a useful framework for fitting parameters of stochastic small world network models where simulation of the system is straightforward but expressing a likelihood is cumbersome.
Advanced InSAR imaging for dune mapping
NASA Astrophysics Data System (ADS)
Havivi, Shiran; August, Yitzhak; Blumberg, Dan G.; Rotman, Stanley R.
2015-04-01
Aeolian morphologies are formed in the presence of sufficient wind energy and available particles. These processes occur naturally or are further enhanced or reduced by human intervention. The dimensions of change are dependent primarily on the wind energy and surface properties. Since the 1970's, remote sensing imagery both optical and radar, are used for documentation and interpretation of the geomorphologic changes of sand dunes. Remote sensing studies of Aeolian morphologies is mostly useful to document major changes, yet, subtle changes, occurring in a period of days or months in scales of centimeters, are very difficult to detect in imagery. Interferometric Synthetic Aperture Radar (InSAR) is an imaging technique for measuring Earth's surface topography and deformation. InSAR images are produced by measuring the radar phase difference between two separated antennas that view the same surface area. Classical InSAR is based on high coherence between two images or more. The output (interferogram) can show subtle changes with an accuracy of several millimeters to centimeters. Very little work has been done on measuring or identifying the changes in dunes using InSAR. The reason is that dunes tend to be less coherent than firm, stable, surfaces. This research aims to demonstrate how interferometric decorrelation, or, coherence change detection, can be used for identifying dune instability. We hypothesize and demonstrate that the loss of radar coherence over time on dunes can be used as an indication of the dune's instability. When SAR images are acquired at sufficiently close intervals one can measure the time it takes to lose coherence and associate this time with geomorphic stability. To achieve our goals, the Nitzanim coastal dunes along the Mediterranean, 40 km south of Tel-Aviv, Israel, were chosen as a case study. The dunes in this area are of varying levels of stability and vegetation cover and have been monitored meteorologically, geomorphologically and extensively in the field. High resolution TerraSAR-X (TSX) images, covering the entire research area were acquired for the period of October 2011 to July 2012 (15 images in total). All images were co-registreted, the first image was used as the master image. A coherence index was calculated for all the images. Analysis was performed in GIS software. The results display minor changes (coherence index in range of 0.4-0.65) on dune crests depending on the dune location relative to its distance from the sea and distance from the city. In addition, field results indicate erosion / deposition of sand in a cumulatively amount of approximately 30mm annually. The results of this study confirm that it is possible to monitor subtle changes in dunes and to identify dune stability or instability, only by the use of SAR images.
Investigating subsidence at volcanoes in northern California using InSAR
NASA Astrophysics Data System (ADS)
Parker, A. L.; Biggs, J.; Annen, C.; Lu, Z.
2013-12-01
Both Medicine Lake Volcano (MLV) and Lassen Volcanic Center (LVC), northern CA, show signs of subsidence at rates of ~1 cm/yr. Leveling and campaign GPS measurements show that MLV has subsided at a constant rate for over 50 years, making the geodetic history of this volcano unique in both its duration and continuity. Here, we summarise and build upon the existing geodetic records at MLV and LVC, using interferometric synthetic aperture radar (InSAR) to extend the time-series of deformation measurements to 2011. We also use the improved spatial resolution of InSAR measurements to investigate causes of long-term subsidence, providing new insight into magmatic storage conditions at MLV and the timescales of deformation due to cooling and crystallization. A large InSAR dataset has been acquired for the volcanoes of northern CA, but application of the data has been limited by extensive noise and incoherence. We analyse multiple datasets from MLV and LVC and, with the use of multi-temporal InSAR analysis methods (noise-based stacking, π-RATE and StaMPS), demonstrate how InSAR may be used more successfully as a monitoring tool in this region. By comparing InSAR results for MLV to past geodetic studies, we demonstrate that subsidence is on going at ~1 cm/yr with no detectable change in rate. We find that the best fitting source geometry to InSAR data is a sill approximated by a horizontal penny-shaped crack, with radius 2 km and depth 11 km, undergoing volume loss at a rate of -0.0022 km3/yr. We discuss possible source mechanisms of long-term subsidence, investigating volume loss due to cooling and crystallization of an intrusion. We calculate the temperature, melt fraction and volume loss of an intrusion over time using petrological information and a numerical thermal model of heat loss by conduction. The geometry of the intrusion is based upon the depth and radius of the penny-shaped crack model. We run simulations for a range of thicknesses between that of a single intrusion (~50 m) and that of the larger column of intrusive material thought to exist beneath the edifice (~7000 m). Using constraints from the geodetic record, we identify a range of sills with volumes < 10 km3 that can account for the deformation recorded at MLV. We use these models to discuss the timing of intrusion and forecast the total duration of cooling. These processes are also significant at LVC and other Cascade volcanoes, where hydrothermal activity is likely to be driven by heat from magmatic intrusions and the exsolution of volatiles that occurs during cooling and crystallization.
A Preliminary Assessment of the S-3A SRAL Performances in SAR Mode
NASA Astrophysics Data System (ADS)
Dinardo, Salvatore; Scharroo, Remko; Bonekamp, Hans; Lucas, Bruno; Loddo, Carolina; Benveniste, Jerome
2016-08-01
The present work aims to assess and characterize the S3-A SRAL Altimeter performance in closed-loop tracking mode and in open ocean conditions. We have processed the Sentinel-3 SAR data products from L0 until L2 using an adaptation of the ESRIN GPOD CryoSat-2 Processor SARvatore.During the Delay-Doppler processing, we have chosen to activate the range zero-padding option.The L2 altimetric geophysical parameters, that are to be validated, are the sea surface height above the ellipsoid (SSH), sea level anomaly (SLA), the significant wave height (SWH) and wind speed (U10), all estimated at 20 Hz.The orbit files are the POD MOE, while the geo- corrections are extracted from the RADS database.In order to assess the accuracy of the wave&wind products, we have been using an ocean wave&wind speed model output (wind speed at 10 meter high above the sea surface) from the ECMWF.We have made a first order approximation of the sea state bias as -4.7% of the SWH.In order to assess the precision performance of SRAL SAR mode, we compute the level of instrumental noise (range, wave height and wind speed) for different conditions of sea state.
ASAR images a diverse set of deformation patterns at Kilauea volcano, Hawai'i
Poland, Michael P.
2007-01-01
Since 2003, 27 independent look angles have been acquired by ENVISAT’s Advanced Synthetic Aperture Radar (ASAR) instrument over the island of Hawai`i, allowing for the formation of thousands of interferograms showing deformation of the ground surface. On Kīlauea volcano, a transition from minor to broad-scale summit inflation was observed by interferograms that span 2003 to 2006. In addition, radar interferometry (InSAR) observations of Kīlauea led to the discovery of several previously unknown areas of localized subsidence in the caldera and along the volcano’s east rift zone. These features are probably caused by the cooling and contraction of accumulated lavas. After November 2005, a surface instability near the point that lava entered the ocean on the south flank of Kīlauea was observed in interferograms. The motion is most likely a result of unbuttressing of a portion of the coast following the collapse of a large lava delta in November 2005. InSAR data can also be used to map lava flow development over time, providing ~30 m spatial resolution maps at approximately monthly intervals. Future applications of InSAR to Kīlauea will probably result in more discoveries and insights, both as the style of volcano deformation changes and as data from new instruments are acquired.
New insights into earthquake precursors from InSAR.
Moro, Marco; Saroli, Michele; Stramondo, Salvatore; Bignami, Christian; Albano, Matteo; Falcucci, Emanuela; Gori, Stefano; Doglioni, Carlo; Polcari, Marco; Tallini, Marco; Macerola, Luca; Novali, Fabrizio; Costantini, Mario; Malvarosa, Fabio; Wegmüller, Urs
2017-09-20
We measured ground displacements before and after the 2009 L'Aquila earthquake using multi-temporal InSAR techniques to identify seismic precursor signals. We estimated the ground deformation and its temporal evolution by exploiting a large dataset of SAR imagery that spans seventy-two months before and sixteen months after the mainshock. These satellite data show that up to 15 mm of subsidence occurred beginning three years before the mainshock. This deformation occurred within two Quaternary basins that are located close to the epicentral area and are filled with sediments hosting multi-layer aquifers. After the earthquake, the same basins experienced up to 12 mm of uplift over approximately nine months. Before the earthquake, the rocks at depth dilated, and fractures opened. Consequently, fluids migrated into the dilated volume, thereby lowering the groundwater table in the carbonate hydrostructures and in the hydrologically connected multi-layer aquifers within the basins. This process caused the elastic consolidation of the fine-grained sediments within the basins, resulting in the detected subsidence. After the earthquake, the fractures closed, and the deep fluids were squeezed out. The pre-seismic ground displacements were then recovered because the groundwater table rose and natural recharge of the shallow multi-layer aquifers occurred, which caused the observed uplift.
Asplund, Kjell; Hulter Åsberg, Kerstin; Appelros, Peter; Bjarne, Daniela; Eriksson, Marie; Johansson, Asa; Jonsson, Fredrik; Norrving, Bo; Stegmayr, Birgitta; Terént, Andreas; Wallin, Sari; Wester, Per-Olov
2011-04-01
Riks-Stroke, the Swedish Stroke Register, is the world's longest-running national stroke quality register (established in 1994) and includes all 76 hospitals in Sweden admitting acute stroke patients. The development and maintenance of this sustainable national register is described. Riks-Stroke includes information on the quality of care during the acute phase, rehabilitation and secondary prevention of stroke, as well as data on community support. Riks-Stroke is unique among stroke quality registers in that patients are followed during the first year after stroke. The data collected describe processes, and medical and patient-reported outcome measurements. The register embraces most of the dimensions of health-care quality (evidence-based, safe, provided in time, distributed fairly and patient oriented). Annually, approximately 25,000 patients are included. In 2009, approximately 320,000 patients had been accumulated (mean age 76-years). The register is estimated to cover 82% of all stroke patients treated in Swedish hospitals. Among critical issues when building a national stroke quality register, the delicate balance between simplicity and comprehensiveness is emphasised. Future developments include direct transfer of data from digital medical records to Riks-Stroke and comprehensive strategies to use the information collected to rapidly implement new evidence-based techniques and to eliminate outdated methods in stroke care. It is possible to establish a sustainable quality register for stroke at the national level covering all hospitals admitting acute stroke patients. Riks-Stroke is fulfilling its main goals to support continuous quality improvement of Swedish stroke services and serve as an instrument for following up national stroke guidelines. © 2010 The Authors. International Journal of Stroke © 2010 World Stroke Organization.
Kim, Hyungseup; Park, Yunjong; Ko, Youngwoon; Mun, Yeongjin; Lee, Sangmin; Ko, Hyoungho
2018-01-01
Wearable healthcare systems require measurements from electrocardiograms (ECGs) and photoplethysmograms (PPGs), and the blood pressure of the user. The pulse transit time (PTT) can be calculated by measuring the ECG and PPG simultaneously. Continuous-time blood pressure without using an air cuff can be estimated by using the PTT. This paper presents a biosignal acquisition integrated circuit (IC) that can simultaneously measure the ECG and PPG for wearable healthcare applications. Included in this biosignal acquisition circuit are a voltage mode instrumentation amplifier (IA) for ECG acquisition and a current mode transimpedance amplifier for PPG acquisition. The analog outputs from the ECG and PPG channels are muxed and converted to digital signals using 12-bit successive approximation register (SAR) analog-to-digital converter (ADC). The proposed IC is fabricated by using a standard 0.18 μm CMOS process with an active area of 14.44 mm2. The total current consumption for the multichannel IC is 327 μA with a 3.3 V supply. The measured input referred noise of ECG readout channel is 1.3 μVRMS with a bandwidth of 0.5 Hz to 100 Hz. And the measured input referred current noise of the PPG readout channel is 0.122 nA/√Hz with a bandwidth of 0.5 Hz to 100 Hz. The proposed IC, which is implemented using various circuit techniques, can measure ECG and PPG signals simultaneously to calculate the PTT for wearable healthcare applications.
Minimally-Invasive Neural Interface for Distributed Wireless Electrocorticogram Recording Systems
Chang, Sun-Il
2018-01-01
This paper presents a minimally-invasive neural interface for distributed wireless electrocorticogram (ECoG) recording systems. The proposed interface equips all necessary components for ECoG recording, such as the high performance front-end integrated circuits, a fabricated flexible microelectrode array, and wireless communication inside a miniaturized custom-made platform. The multiple units of the interface systems can be deployed to cover a broad range of the target brain region and transmit signals via a built-in intra-skin communication (ISCOM) module. The core integrated circuit (IC) consists of 16-channel, low-power push-pull double-gated preamplifiers, in-channel successive approximation register analog-to-digital converters (SAR ADC) with a single-clocked bootstrapping switch and a time-delayed control unit, an ISCOM module for wireless data transfer through the skin instead of a power-hungry RF wireless transmitter, and a monolithic voltage/current reference generator to support the aforementioned analog and mixed-signal circuit blocks. The IC was fabricated using 250 nm CMOS processes in an area of 3.2 × 0.9 mm2 and achieved the low-power operation of 2.5 µW per channel. Input-referred noise was measured as 5.62 µVrms for 10 Hz to 10 kHz and ENOB of 7.21 at 31.25 kS/s. The implemented system successfully recorded multi-channel neural activities in vivo from a primate and demonstrated modular expandability using the ISCOM with power consumption of 160 µW. PMID:29342103
Minimally-Invasive Neural Interface for Distributed Wireless Electrocorticogram Recording Systems.
Chang, Sun-Il; Park, Sung-Yun; Yoon, Euisik
2018-01-17
This paper presents a minimally-invasive neural interface for distributed wireless electrocorticogram (ECoG) recording systems. The proposed interface equips all necessary components for ECoG recording, such as the high performance front-end integrated circuits, a fabricated flexible microelectrode array, and wireless communication inside a miniaturized custom-made platform. The multiple units of the interface systems can be deployed to cover a broad range of the target brain region and transmit signals via a built-in intra-skin communication (ISCOM) module. The core integrated circuit (IC) consists of 16-channel, low-power push-pull double-gated preamplifiers, in-channel successive approximation register analog-to-digital converters (SAR ADC) with a single-clocked bootstrapping switch and a time-delayed control unit, an ISCOM module for wireless data transfer through the skin instead of a power-hungry RF wireless transmitter, and a monolithic voltage/current reference generator to support the aforementioned analog and mixed-signal circuit blocks. The IC was fabricated using 250 nm CMOS processes in an area of 3.2 × 0.9 mm² and achieved the low-power operation of 2.5 µW per channel. Input-referred noise was measured as 5.62 µV rms for 10 Hz to 10 kHz and ENOB of 7.21 at 31.25 kS/s. The implemented system successfully recorded multi-channel neural activities in vivo from a primate and demonstrated modular expandability using the ISCOM with power consumption of 160 µW.
Monitoring change in the Bering Glacier region, Alaska: Using Landsat TM and ERS-1 imagery
DOE Office of Scientific and Technical Information (OSTI.GOV)
Payne, J.F.; Coffeen, M.; Macleod, R.D.
1997-06-01
The Bering Glacier is the largest (5,180 km{sup 2}) and longest (191 km) glacier in continental North America. This glacier is one of about 200 temperate glaciers in the Alaska/Canada region that are known to surge. Surges at the Bering Glacier typically occur on a 20-30 year cycle. The objective of this project was to extract information regarding the position of the terminus of the glacier from historic aerial photography, early 20{sup th} century ground photography, Landsat Thematic Mapper (TM) satellite data, and European Space Agency, Synthetic Aperture RADAR (ERS-1 SAR) data and integrate it into a single digital databasemore » that would lend itself to change detection analysis. ERS-1 SAR data was acquired from six dates between 1992-95 and was terrain corrected and co-registered A single Landsat TM image from June 1991 was used as the base image for classifying land cover types. Historic locations of the glacier terminus were generated using traditional photo interpretation techniques from aerial and ground photography. The result of this platform combination, along with the historical data, is providing land managers with the unique opportunity to generate complete assessments of glacial movement this century and determine land cover changes which may impact wildlife and recreational opportunities.« less
12 CFR 563.180 - Suspicious Activity Reports and other reports and statements.
Code of Federal Regulations, 2013 CFR
2013-01-01
....C. 1813(u) and 1818(b)(9)). (iii) SAR means a Suspicious Activity Report. (3) SARs required. A... action. (11) Obtaining SARs. A savings association or service corporation may obtain SARs and the...) Confidentiality of SARs. A SAR, and any information that would reveal the existence of a SAR, are confidential...
12 CFR 563.180 - Suspicious Activity Reports and other reports and statements.
Code of Federal Regulations, 2014 CFR
2014-01-01
....C. 1813(u) and 1818(b)(9)). (iii) SAR means a Suspicious Activity Report. (3) SARs required. A... action. (11) Obtaining SARs. A savings association or service corporation may obtain SARs and the...) Confidentiality of SARs. A SAR, and any information that would reveal the existence of a SAR, are confidential...
12 CFR 563.180 - Suspicious Activity Reports and other reports and statements.
Code of Federal Regulations, 2012 CFR
2012-01-01
....C. 1813(u) and 1818(b)(9)). (iii) SAR means a Suspicious Activity Report. (3) SARs required. A... action. (11) Obtaining SARs. A savings association or service corporation may obtain SARs and the...) Confidentiality of SARs. A SAR, and any information that would reveal the existence of a SAR, are confidential...
Ice Types in the Beaufort Sea, Alaska
NASA Technical Reports Server (NTRS)
2003-01-01
Determining the amount and type of sea ice in the polar oceans is crucial to improving our knowledge and understanding of polar weather and long term climate fluctuations. These views from two satellite remote sensing instruments; the synthetic aperture radar (SAR) on board the RADARSAT satellite and the Multi-angle Imaging SpectroRadiometer (MISR), illustrate different methods that may be used to assess sea ice type. Sea ice in the Beaufort Sea off the north coast of Alaska was classified and mapped in these concurrent images acquired March 19, 2001 and mapped to the same geographic area.To identify sea ice types, the National Oceanic and Atmospheric Administration (NOAA) National Ice Center constructs ice charts using several data sources including RADARSAT SAR images such as the one shown at left. SAR classifies sea ice types primarily by how the surface and subsurface roughness influence radar backscatter. In the SAR image, white lines delineate different sea ice zones as identified by the National Ice Center. Regions of mostly multi-year ice (A) are separated from regions with large amounts of first year and younger ice (B-D), and the dashed white line at bottom marks the coastline. In general, sea ice types that exhibit increased radar backscatter appear bright in SAR and are identified as rougher, older ice types. Younger, smoother ice types appear dark to SAR. Near the top of the SAR image, however, red arrows point to bright areas in which large, crystalline 'frost flowers' have formed on young, thin ice, causing this young ice type to exhibit an increased radar backscatter. Frost flowers are strongly backscattering at radar wavelengths (cm) due to both surface roughness and the high salinity of frost flowers, which causes them to be highly reflective to radar energy.Surface roughness is also registered by MISR, although the roughness observed is at a different spatial scale. Older, rougher ice areas are predominantly backward scattering to the MISR cameras, whereas younger, smoother ice types are predominantly forward scattering. The MISR map at right was generated using a statistical classification routine (called ISODATA) and analyzed using ice charts from the National Ice Center. Five classes of sea ice were found based upon the classification of MISR angular data. These are described, based on interpretation of the SAR image, by the image key. Very smooth ice areas that are predominantly forward scattering are colored red. Frost flowers are largely smooth to the MISR visible band sensor and are mapped as forward scattering. Areas mapped as blue are predominantly backward scattering, and the other three classes have statistically distinct angular signatures and fall within the middle of the forward/backward scattering continuum. Some areas that may be first year or younger ice between the multi year ice floes are not discernible to SAR, illustrating how MISR potentially can make a unique contribution to sea ice mapping.The Multi-angle Imaging SpectroRadiometer observes the daylit Earth continuously and every 9 days views the entire globe between 82 degrees north and 82 degrees south latitude. This data product was generated from a portion of the imagery acquired during Terra orbit 6663. The MISR image has been cropped to include an area that is 200 kilometers wide, and utilizes data from blocks 30 to 33 within World Reference System-2 path 71.MISR was built and is managed by NASA's Jet Propulsion Laboratory,Pasadena, CA, for NASA's Office of Earth Science, Washington, DC. The Terra satellite is managed by NASA's Goddard Space Flight Center, Greenbelt, MD. JPL is a division of the California Institute of Technology.NASA Astrophysics Data System (ADS)
Mayorga Torres, Tannia
2014-05-01
Using DInSAR as a tool to detect unstable terrain areas in an Andes region in Ecuador (South America) 1. INTRODUCTION Monitoring landslides is a mandatory task in charge on the National Institute of Geological Research (INIGEMM) in Ecuador. It is a small country, supposedly will be faster doing monitoring, but what about its geographic characteristics? Lamentably, due to human and financial resources is not possible to put monitoring systems in unstable terrain areas. However, getting ALOS data to accessible price and using open source software to produce interferograms, could be a first step to know steep areas covered by vegetation and where mass movements are not visible. Under this statement, this study is part of the final research in a master study developed at CONAE during 2009-2011, with oral defense in August 2013. As a new technique used in Ecuador, the study processed radar data from ERS-1/2 and ALOS sensor PALSAR for getting differential interferograms, using ROI_PAC software. Stacking DInSAR is applied to get an average of displacement that indicates uplift and subsidence in the whole radar scene that covers two provinces in the Andes region. 2. PROBLEM Mass movements are present in the whole territory, independently of their magnitude and dynamic (slow or fast), they are a latent threat in winter season specially. There are registers of monitoring, such as two GPS's campaigns and artisanal extensometers, which are used to contrast with DInSAR results. However, the campaigns are shorter and extensometers are no trust on all. 3. METHODOLOGY Methodology has four phases of development: (1) Pre-processing of RAW data; (2) Processing of RAW data in ROI_PAC; (3) Post-processing for getting interferograms in units of cm per year; (4) Analysis of the results and comparison with ground truth. Sandwell & Price (1998) proposed Stacking technique to increase the fringes and decrease errors due to the atmosphere, to average several interferograms. L band penetrates deeper into vegetation cover than C band (Raucoules et al., 2007). The study processed ERS with descending orbit and ALOS with ascending orbit, due to the availability of data. Ferretti et al. (2007) said that ERS looks to the right and a slope mainly oriented to the west could have foreshortening effect in ascending orbit. Wei & Sandwell (2010) mention that ALOS in ascending orbit identifies vertical mass movements along fault systems; however, descending data has better geometry to measure mass movements. The study has fewer scenes in descending orbit. For further work, ALOS 2 will let to have more data in descending orbit. 4. CENTRAL CONCLUSIONS For mass movement having high-resolution radar is the best option; however, this data is not useful on all due to cover vegetation. Characterizing mass movements in Ecuador in necessary to put monitoring systems to avoid economic and human lost. Processing ERS and ALOS data was very useful because penetration band results were clearly identified in coherence masks. The result of Stacking DInSAR did not show clearly fringes, indeed the amount of interferograms were no enough for this technique. Researching other DInSAR techniques is necessary due to the singular characteristics of Ecuador. 5. REFERENCES Ferretti Alessandro, Monti-Guarnieri Andrea, Prati Claudio, Rocca Fabio, Massonnet Didier (2007). InSAR Principles: Guidelines for SAR Interferometry Processing and Interpretation (TM-19, Febrero 2007). K. Fletcher, Agencia Espacial Europea Publicaciones. ESTEC. Postbus 2009. 2200 AG Noordwijk. The Netherlands. Raucoules Daniel, Colesanti Carlo, Carnec Claudie (2007). "Use of SAR interferometry for detecting and assessing ground subsidence." C. R. Geoscience 339(289-302): 14. Sandwell David T., Price Evelyn J. (1998). "Phase gradient approach to stacking interferograms." Journal of Geophysical Research 103(N. B12): 30, 183-30, 204. Wei Meng, Sandwell David T (2010). "Decorrelation of L-Band and C-Band Interferometry Over Vegetated Areas in California." Geoscience and Remote Sensing 48(7): 11
False-color L-band image of Manaus region of Brazil
1994-04-13
STS059-S-068 (13 April 1994) --- This false-color L-Band image of the Manaus region of Brazil was acquired by the Spaceborne Imaging Radar-C and X-Band Synthetic Aperture Radar (SIR-C/X-SAR) aboard the Space Shuttle Endeavour on orbit 46 of the mission. The area shown is approximately 8 kilometers by 40 kilometers (5 by 25 miles). At the top of the image are the Solimoes and Rio Negro Rivers just before they combine at Manaus to form the Amazon River. The image is centered at about 3 degrees south latitude, and 61 degrees west longitude. The false colors are created by displaying three L-Band polarization channels; red areas correspond to high backscatter at HH polarization, while green areas exhibit high backscatter at HV polarization. Blue areas show low returns at VV polarization; hence the bright blue colors of the smooth river surfaces. Using this color scheme, green areas in the image are heavily forested, while blue areas are either cleared forest or open water. The yellow and red areas are flooded forest. Between Rio Solimoes and Rio Negro a road can be seen running from some cleared areas (visible as blue rectangles north of Rio Solimoes) north towards a tributary of Rio Negro. SIR-C/X-SAR is part of NASA's Mission to Planet Earth (MTPE). SIR-C/X-SAR radars illuminate Earth with microwaves allowing detailed observations at any time, regardless of weather or sunlight conditions. SIR-C/X-SAR uses three microwave wavelengths: L-Band (24 cm), C-Band (6 cm), and X-Band (3 cm). The multi-frequency data will be used by the international scientific community to better understand the global environment and how it is changing. The SIR-C/X-SAR data, complemented by aircraft and ground studies, will give scientists clearer insights into those environmental changes which are caused by nature and those changes which are induced by human activity. SIR-C was developed by NASA's Jet Propulsion Laboratory (JPL). X-SAR was developed by the Dornire and Alenia Spazio Companies for the German Space Agency, Deutsche Agentur fuer Raumfahrtangelegenheiten (DARA), and the Italian Space Agency, Agenzia Spaziale Italiana (ASI). JPL Photo ID: P-43895
Hu, Xie; Wang, Teng; Pierson, Thomas C.; Lu, Zhong; Kim, Jin-Woo; Cecere, Thomas H.
2016-01-01
Detection of slow or limited landslide movement within broad areas of forested terrain has long been problematic, particularly for the Cascade landslide complex (Washington) located along the Columbia River Gorge. Although parts of the landslide complex have been found reactivated in recent years, the timing and magnitude of motion have not been systematically monitored or interpreted. Here we apply novel time-series strategies to study the spatial distribution and temporal behavior of the landslide movement between 2007 and 2011 using InSAR images from two overlapping L-band ALOS PALSAR-1 satellite tracks. Our results show that the reactivated part has moved approximately 700 mm downslope during the 4-year observation period, while other parts of the landslide complex have generally remained stable. However, we also detect about 300 mm of seasonal downslope creep in a terrain block upslope of the Cascade landslide complex—terrain previously thought to be stable. The temporal oscillation of the seasonal movement can be correlated with precipitation, implying that seasonal movement here is hydrology-driven. The seasonal movement also has a frequency similar to GPS-derived regional ground oscillations due to mass loading by stored rainfall and subsequent rebound but with much smaller magnitude, suggesting different hydrological loading effects. From the time-series amplitude information on terrain upslope of the headscarp, we also re-evaluate the incipient motion related to the 2008 Greenleaf Basin rock avalanche, not previously recognized by traditional SAR/InSAR methods. The approach used in this study can be used to identify active landslides in forested terrain, to track the seasonal movement of landslides, and to identify previously unknown landslide hazards.
Rezai, Ali R; Finelli, Daniel; Nyenhuis, John A; Hrdlicka, Greg; Tkach, Jean; Sharan, Ashwini; Rugieri, Paul; Stypulkowski, Paul H; Shellock, Frank G
2002-03-01
To assess magnetic resonance imaging (MRI)-related heating for a neurostimulation system (Activa Tremor Control System, Medtronic, Minneapolis, MN) used for chronic deep brain stimulation (DBS). Different configurations were evaluated for bilateral neurostimulators (Soletra Model 7426), extensions, and leads to assess worst-case and clinically relevant positioning scenarios. In vitro testing was performed using a 1.5-T/64-MHz MR system and a gel-filled phantom designed to approximate the head and upper torso of a human subject. MRI was conducted using the transmit/receive body and transmit/receive head radio frequency (RF) coils. Various levels of RF energy were applied with the transmit/receive body (whole-body averaged specific absorption rate (SAR); range, 0.98-3.90 W/kg) and transmit/receive head (whole-body averaged SAR; range, 0.07-0.24 W/kg) coils. A fluoroptic thermometry system was used to record temperatures at multiple locations before (1 minute) and during (15 minutes) MRI. Using the body RF coil, the highest temperature changes ranged from 2.5 degrees-25.3 degrees C. Using the head RF coil, the highest temperature changes ranged from 2.3 degrees-7.1 degrees C.Thus, these findings indicated that substantial heating occurs under certain conditions, while others produce relatively minor, physiologically inconsequential temperature increases. The temperature increases were dependent on the type of RF coil, level of SAR used, and how the lead wires were positioned. Notably, the use of clinically relevant positioning techniques for the neurostimulation system and low SARs commonly used for imaging the brain generated little heating. Based on this information, MR safety guidelines are provided. These observations are restricted to the tested neurostimulation system.
Ohtani, Shin; Ushiyama, Akira; Maeda, Machiko; Hattori, Kenji; Kunugita, Naoki; Wang, Jianqing; Ishii, Kazuyuki
2016-01-01
We investigated the thermal effects of radiofrequency electromagnetic fields (RF-EMFs) on the variation in core temperature and gene expression of some stress markers in rats. Sprague-Dawley rats were exposed to 2.14 GHz wideband code division multiple access (W-CDMA) RF signals at a whole-body averaged specific absorption rate (WBA-SAR) of 4 W/kg, which causes behavioral disruption in laboratory animals, and 0.4 W/kg, which is the limit for the occupational exposure set by the International Commission on Non-Ionizing Radiation Protection guideline. It is important to understand the possible in vivo effects derived from RF-EMF exposures at these intensities. Because of inadequate data on real-time core temperature analyses using free-moving animal and the association between stress and thermal effects of RF-EMF exposure, we analyzed the core body temperature under nonanesthetic condition during RF-EMF exposure. The results revealed that the core temperature increased by approximately 1.5°C compared with the baseline and reached a plateau till the end of RF-EMF exposure. Furthermore, we analyzed the gene expression of heat-shock proteins (Hsp) and heat-shock transcription factors (Hsf) family after RF-EMF exposure. At WBA-SAR of 4 W/kg, some Hsp and Hsf gene expression levels were significantly upregulated in the cerebral cortex and cerebellum following exposure for 6 hr/day but were not upregulated after exposure for 3 hr/day. On the other hand, there was no significant change in the core temperature and gene expression at WBA-SAR of 0.4 W/kg. Thus, 2.14-GHz RF-EMF exposure at WBA-SAR of 4 W/kg induced increases in the core temperature and upregulation of some stress markers, particularly in the cerebellum.
(abstract) Monitoring the Freeze/Thaw Transitions in Taiga Forests Using ERS-1 SAR
NASA Technical Reports Server (NTRS)
Rignot, E.; Williams, C.; Donald, K. Mc; Way, J. B.; Zimmerman, R.; Viereck, L.
1994-01-01
Automated recording stations have been installed at the Bonanza Creek Experimental Forest, a Long Term Ecological Research (LTER) site located near Fairbanks, Alaska, in a forest stand of the Tanana River floodplain underlain by discontinuous permafrost. These stations provide a continuous record of dielectric constant and temperature of tree trunks, and soil moisture and temperature profiles down to the root zone. Along with the weather stations deployed at the same location, these measurements provide a continuous record of the environmental and phenologic conditions of the forest during a complete seasonal cycle. At the same time, ERS-1 SAR imaged the study site repeatedly from space to provide radar backscatter measurements of the forest approximately three times a month. Here, we examine the temporal dynamic of ERS-1 SAR measurements in relation with the changing environmental and phenologic state of the forest canopy and of the forest ground layers during the winter/spring and fall/winter transitions of 1992 and 1993. During these transitions, we examine whether changes in radar backscatter observed by ERS-1 may be related to freezing or thawing of the soil and vegetation in order to determine the start and end of the growing season for the forest. The results of this analysis are used in turn to determine whether similar changes are observed over larger regions. Mosaics of SAR data generated along three different North-South Alaskan ERS-1 transects that intercept with our study site are used in combination with hourly air temperature and daily precipitation rates gathered at airport weather stations by the National Weather Service. Results obtained using ERS-1 data collected from January 1992 to mid-1993 will be discussed.
Röschmann, P
1987-01-01
This study presents experimental results about the effective depth of penetration and about the radiofrequency (rf) power absorption in humans as a function of frequency. The frequency range investigated covers 10 up to 220 MHz. For the main part, the results were derived from bench measurements of the quality factor Q, and of the resonance frequency shift due to the loading of the coil. Different types of head-, body-, and surface coils were investigated loaded with volunteers or metallic phantoms. For spin-echo imaging at 2 T (85 MHz), the local specific absorption rate (SAR) was found to be approximately equal to 0.05 W/kg using a pi pulse of 1-ms duration and pulse repetition time TR = 1 s. Measurements of the quality factor Q as a function of frequency show that the SAR depends upon the frequency f according to approximately f2.15. The effective depth of rf penetration as derived drops from 17 cm at 85 MHz to 7 cm at 220 MHz. Head imaging with B1 penetrating from practically all sides into the object should be possible up to 220 MHz (5 T) with SAR values staying within the local limit of 2 W/kg as set by the FDA. Whole-body imaging of large subjects as well as surface coil imaging is depth limited above 100-MHz frequency. Perturbation methods are applied in order to separate the total rf power deposition in the patient into dielectric and magnetic contributions. The observed effects due to interactions of rf magnetic fields with biological tissue contradict predictions based on homogeneous tissue models. A refined tissue model with regions of high electrical conductivity, subdivided by quasi-insulating adipose layers, provides a rationale for a better understanding of the underlying processes. At frequencies below 100 MHz, the rf power deposition in patients is apparently more evenly distributed over the exposed body volume than currently assumed.
Computational dosimetry for grounded and ungrounded human models due to contact current
NASA Astrophysics Data System (ADS)
Chan, Kwok Hung; Hattori, Junya; Laakso, Ilkka; Hirata, Akimasa; Taki, Masao
2013-08-01
This study presents the computational dosimetry of contact currents for grounded and ungrounded human models. The uncertainty of the quasi-static (QS) approximation of the in situ electric field induced in a grounded/ungrounded human body due to the contact current is first estimated. Different scenarios of cylindrical and anatomical human body models are considered, and the results are compared with the full-wave analysis. In the QS analysis, the induced field in the grounded cylindrical model is calculated by the QS finite-difference time-domain (QS-FDTD) method, and compared with the analytical solution. Because no analytical solution is available for the grounded/ungrounded anatomical human body model, the results of the QS-FDTD method are then compared with those of the conventional FDTD method. The upper frequency limit for the QS approximation in the contact current dosimetry is found to be 3 MHz, with a relative local error of less than 10%. The error increases above this frequency, which can be attributed to the neglect of the displacement current. The QS or conventional FDTD method is used for the dosimetry of induced electric field and/or specific absorption rate (SAR) for a contact current injected into the index finger of a human body model in the frequency range from 10 Hz to 100 MHz. The in situ electric fields or SAR are compared with the basic restrictions in the international guidelines/standards. The maximum electric field or the 99th percentile value of the electric fields appear not only in the fat and muscle tissues of the finger, but also around the wrist, forearm, and the upper arm. Some discrepancies are observed between the basic restrictions for the electric field and SAR and the reference levels for the contact current, especially in the extremities. These discrepancies are shown by an equation that relates the current density, tissue conductivity, and induced electric field in the finger with a cross-sectional area of 1 cm2.
NASA Astrophysics Data System (ADS)
Marino, Armando; Hajnsek, Irena
2015-04-01
In this work, the solution of quadratic forms with special application to polarimetric and interferometric covariance matrices is investigated. An analytical solution for the integral of a single quadratic form is derived. Additionally, the integral of the Pol-InSAR coherence (expressed as combination of quadratic forms) is investigated. An approximation for such integral is proposed and defined as Trace coherence. Such approximation is tested on real data to verify that the error is acceptable. The trace coherence can be used for tackle problems related to change detection. Moreover, the use of the Trace coherence in model inversion (as for the RVoG three stage inversion) will be investigated in the future.
InSAR time series analysis of ALOS-2 ScanSAR data and its implications for NISAR
NASA Astrophysics Data System (ADS)
Liang, C.; Liu, Z.; Fielding, E. J.; Huang, M. H.; Burgmann, R.
2017-12-01
The JAXA's ALOS-2 mission was launched on May 24, 2014. It operates at L-band and can acquire data in multiple modes. ScanSAR is the main operational mode and has a 350 km swath, somewhat larger than the 250 km swath of the SweepSAR mode planned for the NASA-ISRO SAR (NISAR) mission. ALOS-2 has been acquiring a wealth of L-band InSAR data. These data are of particular value in areas of dense vegetation and high relief. The InSAR technical development for ALOS-2 also enables the preparation for the upcoming NISAR mission. We have been developing advanced InSAR processing techniques for ALOS-2 over the past two years. Here, we report the important issues for doing InSAR time series analysis using ALOS-2 ScanSAR data. First, we present ionospheric correction techniques for both regular ScanSAR InSAR and MAI (multiple aperture InSAR) ScanSAR InSAR. We demonstrate the large-scale ionospheric signals in the ScanSAR interferograms. They can be well mitigated by the correction techniques. Second, based on our technical development of burst-by-burst InSAR processing for ALOS-2 ScanSAR data, we find that the azimuth Frequency Modulation (FM) rate error is an important issue not only for MAI, but also for regular InSAR time series analysis. We identify phase errors caused by azimuth FM rate errors during the focusing process of ALOS-2 product. The consequence is mostly a range ramp in the InSAR time series result. This error exists in all of the time series results we have processed. We present the correction techniques for this error following a theoretical analysis. After corrections, we present high quality ALOS-2 ScanSAR InSAR time series results in a number of areas. The development for ALOS-2 can provide important implications for NISAR mission. For example, we find that in most cases the relative azimuth shift caused by ionosphere can be as large as 4 m in a large area imaged by ScanSAR. This azimuth shift is half of the 8 m azimuth resolution of the SweepSAR mode planned for NISAR, which implies that a good coregistration strategy for NISAR's SweepSAR mode is geometrical coregistration followed by MAI or spectral diversity analysis. Besides, our development also provides implications for the processing and system parameter requirements of NISAR, such as the accuracy requirement of azimuth FM rate and range timing.
Studies of ice sheet hydrology using SAR
NASA Technical Reports Server (NTRS)
Bindschadler, R. A.; Vornberger, P. L.
1989-01-01
Analysis of SAR data of the Greenland ice sheet in summer and winter suggest the use of SAR to monitor the temporal hydrology of ice sheets. Comparisons of each SAR data set with summer Landsat TM imagery show an areal-positive correlation with summer SAR data and a negative correlation with winter SAR data. It is proposed that the summer SAR data are most sensitive to the variable concentrations of free water in the surface snow and that the winter SAR data indicate variations in snow grain size.
Chen, Chuan; Zhang, Xu; Shang, Fei; Sun, Haipeng; Sun, Baolin; Xue, Ting
2015-08-01
Staphylococcus aureus is an important Gram-positive pathogen responsible for numerous diseases ranging from localized skin infections to life-threatening systemic infections. The virulence of S. aureus is essentially determined by a wide spectrum of factors, including cell wall-associated proteins and secreted toxins that are precisely controlled in response to environmental changes. GGDEF domain protein from Staphylococcus (GdpS) is the only conserved staphylococcal GGDEF domain protein that is involved not in c-di-GMP synthesis but in the virulence regulation of S. aureus NCTC8325. Our previous study showed that the inactivation of gdpS generates an extensive change of virulence factors together with, in particular, a major Spa (protein A) surface protein. As reported, sarS is a direct positive regulator of spa. The decreased transcript levels of sarS in the gdpS mutant compared with the parental NCTC8325 strain suggest that gdpS affects spa through interaction with sarS. In this study, site mutation and complementary experiments showed that the translation product of gdpS was not involved in the regulation of transcript levels of sarS. We found that gdpS functioned through direct RNA-RNA base pairing with the 5' untranslated region (5'UTR) of sarS mRNA and that a putative 18-nucleotide region played a significant role in the regulatory process. Furthermore, the mRNA half-life analysis of sarS in the gdpS mutant showed that gdpS positively regulates the mRNA levels of sarS by contributing to the stabilization of sarS mRNA, suggesting that gdpS mRNA may regulate spa expression in an RNA-dependent pathway. Copyright © 2015, American Society for Microbiology. All Rights Reserved.
Liu, Ye V.; Massare, Michael J.; Barnard, Dale L.; Kort, Thomas; Nathan, Margret; Wang, Lei; Smith, Gale
2011-01-01
SARS-CoV was the cause of the global pandemic in 2003 that infected over 8000 people in 8 months. Vaccines against SARS are still not available. We developed a novel method to produce high levels of a recombinant SARS virus-like particles (VLPs) vaccine containing the SARS spike (S) protein and the influenza M1 protein using the baculovirus insect cell expression system. These chimeric SARS VLPs have a similar size and morphology to the wild type SARS-CoV. We tested the immunogenicity and protective efficacy of purified chimeric SARS VLPs and full length SARS S protein vaccines in a mouse lethal challenge model. The SARS VLP vaccine, containing 0.8 μg of SARS S protein, completely protected mice from death when administered intramuscular (IM) or intranasal (IN) routes in the absence of an adjuvant. Likewise, the SARS VLP vaccine, containing 4 μg of S protein without adjuvant, reduced lung virus titer to below detectable level, protected mice from weight loss, and elicited a high level of neutralizing antibodies against SARS-CoV. Sf9 cell-produced full length purified SARS S protein was also an effective vaccine against SARS-CoV but only when co-administered IM with aluminum hydroxide. SARS-CoV VLPs are highly immunogenic and induce neutralizing antibodies and provide protection against lethal challenge. Sf9 cell-based VLP vaccines are a potential tool to provide protection against novel pandemic agents. PMID:21762752
NASA Astrophysics Data System (ADS)
Bignami, C.; Moro, M.; Saroli, M.; Stramondo, S.; Albano, M.; Falcucci, E.; Gori, S.; Doglioni, C.; Polcari, M.; Tallini, M.; Macerola, L.; Novali, F.; Costantini, M.; Malvarosa, F.; Wegmüller, U.
2017-12-01
In modern seismology, the identification of earthquake precursors is one of the most important issue to investigate on. Precursor indicators based on the use of updated and most satellite advanced geodetic techniques such as GPS and SAR interferometry, have not been conclusively identified so far. However, the latest progress in terms of new satellite missions and processing algorithms may bring this goal closer. Here we present evidence of ground deformation signals preceding the 2009 L'Aquila earthquake, which have been observed using multi-temporal InSAR techniques. We exploited a wide dataset from RADARSAT2, ENVISAT and COSMO-SkyMed missions to derive mean velocity and ground acceleration maps of the epicentral area, for a time span of approximately 6 years before the earthquake and about one year after the earthquake. The maps of ground accelerations before the mainshock, have allowed the identification of two peculiar displacement patterns, well localized in two Quaternary basins, close to the focal volume of the seismic event (Mw 6.3) that hit the city of L'Aquila on 6 April 2009. In these two regions, a significant subsidence began approximately three years before the earthquake, reaching a value of about 1.5 cm, and persisted until the earthquake. Conversely, in the post-seismic phase, the two basins showed an uplift, with velocities approximately of 5 to 18 mm/yr. The deep knowledge of the geological, hydrogeological and geotechnical setting of the area has provided a plausible explanation of the observed phenomenon. The two Quaternary basins are filled with sediments that host multi-layer aquifers that are hydrologically connected with the neighbouring carbonatic hydrostructures. Before the earthquake, the rocks at depth have dilated and fractures opened. Consequently, fluids have migrated into the dilated volume causing the lowering the groundwater table in the carbonate hydrostructures and in the hydrologically connected multi-layer aquifers within the two basins. Thus, the consolidation of the fine-grained sediments within the basins have occurred, causing the detected subsidence. After the earthquake, the fractures have closed, the deep fluids were squeezed out, and the pre-seismic subsidence was recovered because of the rise of the groundwater table, thus causing the observed uplift.
Observation of high-resolution wind fields and offshore wind turbine wakes using TerraSAR-X imagery
NASA Astrophysics Data System (ADS)
Gies, Tobias; Jacobsen, Sven; Lehner, Susanne; Pleskachevsky, Andrey
2014-05-01
1. Introduction Numerous large-scale offshore wind farms have been built in European waters and play an important role in providing renewable energy. Therefore, knowledge of behavior of wakes, induced by large wind turbines and their impact on wind power output is important. The spatial variation of offshore wind turbine wake is very complex, depending on wind speed, wind direction, ambient atmospheric turbulence and atmospheric stability. In this study we demonstrate the application of X-band TerraSAR-X (TS-X) data with high spatial resolution for studies on wind turbine wakes in the near and far field of the offshore wind farm Alpha Ventus, located in the North Sea. Two cases which different weather conditions and different wake pattern as observed in the TS-X image are presented. 2. Methods The space-borne synthetic aperture radar (SAR) is a unique sensor that provides two-dimensional information on the ocean surface. Due to their high resolution, daylight and weather independency and global coverage, SARs are particularly suitable for many ocean and coastal applications. SAR images reveal wind variations on small scales and thus represent a valuable means in detailed wind-field analysis. The general principle of imaging turbine wakes is that the reduced wind speed downstream of offshore wind farms modulates the sea surface roughness, which in turn changes the Normalized Radar Cross Section (NRCS, denoted by σ0) in the SAR image and makes the wake visible. In this study we present two cases at the offshore wind farm Alpha Ventus to investigate turbine-induced wakes and the retrieved sea surface wind field. Using the wind streaks, visible in the TS-X image and the shadow behind the offshore wind farm, induced by turbine wake, the sea surface wind direction is derived and subsequently the sea surface wind speed is calculated using the latest generation of wind field algorithm XMOD2. 3. Case study alpha ventus Alpha Ventus is located approximately 45 km from the coast of Borkum, Germany, and consists of twelve 5-Megawatt wind power turbines. The retrieved results are validated by comparing with QuikSCAT measurements, the results of the German Weather Service (DWD) atmospheric model and in-situ measurements of wind speed and wind direction, obtained from the research platform FiNO1, installed 400 m west of Alpha Ventus. 4. Conclusion In the presented case study we quantify the wake characteristics of wake length, wake width, maximum velocity de?cit, wake merging and wake meandering. We show that SAR has the capability to map the sea surface two-dimensionally in high spatial resolution which provides a unique opportunity to observe spatial characteristics of offshore wind turbine wakes. The SAR derived information can support offshore wind farming with respect to optimal siting and design and help to estimate their effects on the environment.
SAR matrices: automated extraction of information-rich SAR tables from large compound data sets.
Wassermann, Anne Mai; Haebel, Peter; Weskamp, Nils; Bajorath, Jürgen
2012-07-23
We introduce the SAR matrix data structure that is designed to elucidate SAR patterns produced by groups of structurally related active compounds, which are extracted from large data sets. SAR matrices are systematically generated and sorted on the basis of SAR information content. Matrix generation is computationally efficient and enables processing of large compound sets. The matrix format is reminiscent of SAR tables, and SAR patterns revealed by different categories of matrices are easily interpretable. The structural organization underlying matrix formation is more flexible than standard R-group decomposition schemes. Hence, the resulting matrices capture SAR information in a comprehensive manner.
SARS Grid--an AG-based disease management and collaborative platform.
Hung, Shu-Hui; Hung, Tsung-Chieh; Juang, Jer-Nan
2006-01-01
This paper describes the development of the NCHC's Severe Acute Respiratory Syndrome (SARS) Grid project-An Access Grid (AG)-based disease management and collaborative platform that allowed for SARS patient's medical data to be dynamically shared and discussed between hospitals and doctors using AG's video teleconferencing (VTC) capabilities. During the height of the SARS epidemic in Asia, SARS Grid and the SARShope website significantly curved the spread of SARS by helping doctors manage the in-hospital and in-home care of quarantined SARS patients through medical data exchange and the monitoring of the patient's symptoms. Now that the SARS epidemic has ended, the primary function of the SARS Grid project is that of a web-based informatics tool to increase pubic awareness of SARS and other epidemic diseases. Additionally, the SARS Grid project can be viewed and further studied as an outstanding model of epidemic disease prevention and/or containment.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Buchanan, Rebecca A.; Skalski, John R.
2007-12-07
In 2005, the University of Washington developed a new statistical model to analyze the combined juvenile and adult detection histories of PIT-tagged salmon migrating through the Federal Columbia River Power System (FCRPS). This model, implemented by software Program ROSTER (River-Ocean Survival and Transportation Effects Routine), has been used to estimate survival and transportation effects on large temporal and spatial scales for PIT-tagged hatchery spring and summer Chinook salmon and steelhead released in the Snake River Basin from 1996 to 2003. Those results are reported here. Annual estimates of the smolt-to-adult return ratio (SAR), juvenile inriver survival from Lower Granite tomore » Bonneville, the ocean return probability from Bonneville to Bonneville, and adult upriver survival from Bonneville to Lower Granite are reported. Annual estimates of transport-inriver (T/I) ratios and differential post-Bonneville mortality (D) are reported on both a systemwide basis, incorporating all transport dams analyzed, and a dam-specific basis. Transportation effects are estimated only for dams where at least 5,000 tagged smolts were transported from a given upstream release group. Because few tagged hatchery steelhead were transported in these years, no transportation effects are estimated for steelhead. Performance measures include age-1-ocean adult returns for steelhead, but not for Chinook salmon. Annual estimates of SAR from Lower Granite back to Lower Granite averaged 0.71% with a standard error (SE) of 0.18% for spring Chinook salmon from the Snake River Basin for tagged groups released from 1996 through 2003, omitting age-1-ocean (jack) returns. For summer Chinook salmon from the Snake River Basin, the estimates of annual SAR averaged 1.15% (SE=0.31%). Only for the release years 1999 and 2000 did the Chinook SAR approach the target value of 2%, identified by the NPCC as the minimum SAR necessary for recovery. Annual estimates of SAR for hatchery steelhead from the Snake River Basin averaged 0.45% (SE=0.11%), including age-1-ocean returns, for release years 1996 through 2003. For release years when the ocean return probability from Bonneville back to Bonneville could be estimated (i.e., 1999 through 2003), it was estimated that on average approximately 86% of the total integrated mortality for nontransported, tagged hatchery spring and summer Chinook, and 74% for steelhead, occurred during the ocean life stage (i.e., from Bonneville to Bonneville). This suggests that additional monitoring and research efforts should include the ocean and estuary environment. Annual estimates of the systemwide T/I are weighted averages of the dam-specific T/I ratios for each transport dam (with {ge} 5,000 tagged fish transported), weighted by the probabilities of being transported at each dam. The systemwide T/I compares the observed SAR under the existing transportation system with the expected SAR if the transportation system had not been operated. Estimates of 1.0 indicate that the systemwide transportation program has no effect on SAR, while estimates > 1.0 indicate that the transportation program increases SAR. Excluding the 2001 release group, the geometric mean of the systemwide T/I estimates for hatchery spring Chinook salmon from the Snake River Basin was 1.15 (SE=0.03) for release years 1997 through 2003. The geometric mean of the systemwide T/I estimates for hatchery summer Chinook salmon from the Snake River Basin was 1.28 (SE=0.13) for release years 1997 through 2000 and 2003. Estimates were much higher for the 2001 release groups. These estimates reflect transportation from Lower Granite and/or Little Goose for most release years, depending on the number of tagged smolts actually transported at each dam during each release year. Differential post-Bonneville mortality (D) is the ratio of post-Bonneville survival to Lower Granite Dam of transported fish to that of nontransported ('inriver') fish. Excluding the 2001 release year, the geometric mean of the D estimates for hatchery spring Chinook salmon from the Snake River Basin was 1.00 (SE=0.09) for release years 1997 through 2003. For hatchery summer Chinook salmon from the Snake River Basin, the geometric mean of the D estimates was 1.32 (SE=0.27) for release years 1997 through 2000 and 2003. These estimates reflect transportation from Lower Granite and/or Little Goose, depending on the number of tagged smolts actually transported at each dam during each release year. Approximately half the point estimates of D for both spring and summer Chinook salmon were 1.0 or greater, indicating that for those release groups, transported fish did not have lower ocean and adult survival than nontransported fish. For those years with estimates of D < 1.0, the systemwide T/I estimates were always {ge} 1.0, indicating that despite lower ocean and adult survival of transported fish, transportation did not lower SAR overall.« less
12 CFR 21.11 - Suspicious Activity Report.
Code of Federal Regulations, 2014 CFR
2014-01-01
... Activity Report. (c) SARs required. A national bank shall file a SAR with the appropriate Federal law... supervisory action. (j) Obtaining SARs. A national bank may obtain SARs and the Instructions from the appropriate OCC District Office listed in 12 CFR part 4. (k) Confidentiality of SARs. A SAR, and any...
12 CFR 21.11 - Suspicious Activity Report.
Code of Federal Regulations, 2013 CFR
2013-01-01
... Activity Report. (c) SARs required. A national bank shall file a SAR with the appropriate Federal law... supervisory action. (j) Obtaining SARs. A national bank may obtain SARs and the Instructions from the appropriate OCC District Office listed in 12 CFR part 4. (k) Confidentiality of SARs. A SAR, and any...
Controlling Data Collection to Support SAR Image Rotation
Doerry, Armin W.; Cordaro, J. Thomas; Burns, Bryan L.
2008-10-14
A desired rotation of a synthetic aperture radar (SAR) image can be facilitated by adjusting a SAR data collection operation based on the desired rotation. The SAR data collected by the adjusted SAR data collection operation can be efficiently exploited to form therefrom a SAR image having the desired rotational orientation.
NASA Astrophysics Data System (ADS)
Cao, N.; Lee, H.; Zaugg, E.; Shrestha, R. L.; Carter, W. E.; Glennie, C. L.; Wang, G.; Lu, Z.; Diaz, J. C. F.
2016-12-01
Synthetic aperture radar (SAR) interferometry (InSAR) is a technique which uses two or more SAR images of the same area to estimate landscape topography or ground surface displacement. Differential InSAR (DInSAR) is capable of measuring ground displacements at the millimeter level, but a major drawback of traditional DInSAR is that only the deformation along the line-of-sight direction can be detected. Because most of the current spaceborne SAR systems have near-polar, sun-synchronous orbits, deformation measurements in the South-North direction are limited (except for polar regions). Compared with spaceborne SAR, airborne SAR systems have the advantages of flexible scanning geometry and revisit time, high spatial resolution, and no ionospheric distortion. In this study, we present a case study of the Slumgullion landslide conducted in July 2015 to assess an airborne SAR system known as ARTEMIS SlimSAR, which is a compact, modular, and multi-frequency radar system. The Slumgullion landslide, located in the San Juan Mountains near Lake City, Colorado is a long-term slow moving landslide that moves downhill continuously. For this study, the L-band SlimSAR was installed and data were collected on July 3, 7, and 10 and processed using the time-domain backprojection algorithm. GPS surveys and spaceborne DInSAR analysis using COSMO-SkyMed images were also conducted to verify the performance of the airborne SAR system. The airborne DInSAR results showed satisfying agreement with the GPS and spaceborne DInSAR results. The root mean square of the differences between the SlimSAR, and GPS and satellite derived velocities, were 0.6 mm/day, and 0.9 mm/day, respectively. A 3-D deformation map over Slumgullion landslide was generated, which displayed distinct correlation between the landslide motion and topography. This study also indicated that the primary source of the error for the SlimSAR system is the trajectory turbulences of the aircraft. The effect of the trajectory turbulences is analyzed and several possible solutions are proposed to improve the airborne SAR performance. In the long run, an improved airborne SAR system will open avenues for differential interferometry to be used in scientific studies and commercial applications previously prohibited by orbital constraints of spaceborne SAR.
Radar properties of the Huygens Landing Site on Titan
NASA Astrophysics Data System (ADS)
Lorenz, Ralph; Cassini RADAR Team
2006-09-01
The Huygens landing site on Titan was not expected to be observed with SAR imaging by the Cassini RADAR until late in the nominal tour. However, better-than-expected performance, permitting operation at higher altitudes and thus over longer times than originally anticipated, has permitted two observations of the landing site. The first was an extension to the 5-beam SAR swath on T8 (October 2005) from altitudes of 4000km to 5000km ; the second was an experimental observation at an altitude range of 10,000km-13,000km using custom pointing and SAR-processing only the central high-gain beam. The latter 'experimental' observation opens a new capability (see also the abstract by West et al) for observing targets of interest with a resolution of approximately 1-2km. Here we compare the two images, which have slightly different incidence angles and look azimuths, noting correlations and differences. These can also be compared with the optical image mosaic from the Huygens descent imager DISR. Some correlations exist (notably the two prominent dark lines - linear sand dunes) but there are many differences. Additional information on the radar properties of the landing site can be derived from the Huygens radar altimeter, and the intensity of the probe's radio signal received as Cassini set on the horizon, a fortuitous bistatic scattering experiment.
Zheng, Minxue; Fukuyama, Kaoru; Sanga-Ngoie, Kazadi
2013-12-31
Spatial variation and temporal changes in ground subsidence over the Nobi Plain, Central Japan, are assessed using GIS techniques and ground level measurements data taken over this area since the 1970s. Notwithstanding the general slowing trend observed in ground subsidence over the plains, we have detected ground rise at some locations, more likely due to the ground expansion because of recovering groundwater levels and the tilting of the Nobi land mass. The problem of non-availability of upper-air meteorological information, especially the 3-dimensional water vapor distribution, during the JERS-1 observational period (1992-1998) was solved by applying the AWC (analog weather charts) method onto the high-precision GPV-MSM (Grid Point Value of Meso-Scale Model) water-vapor data to find the latter's matching meteorological data. From the selected JERS-1 interferometry pair and the matching GPV-MSM meteorological data, the atmospheric path delay generated by water vapor inhomogeneity was then quantitatively evaluated. A highly uniform spatial distribution of the atmospheric delay, with a maximum deviation of approximately 38 mm in its horizontal distribution was found over the Plain. This confirms the effectiveness of using GPV-MSM data for SAR differential interferometric analysis, and sheds thus some new light on the possibility of improving InSAR analysis results for land subsidence applications.
Zheng, Minxue; Fukuyama, Kaoru; Sanga-Ngoie, Kazadi
2014-01-01
Spatial variation and temporal changes in ground subsidence over the Nobi Plain, Central Japan, are assessed using GIS techniques and ground level measurements data taken over this area since the 1970s. Notwithstanding the general slowing trend observed in ground subsidence over the plains, we have detected ground rise at some locations, more likely due to the ground expansion because of recovering groundwater levels and the tilting of the Nobi land mass. The problem of non-availability of upper-air meteorological information, especially the 3-dimensional water vapor distribution, during the JERS-1 observational period (1992–1998) was solved by applying the AWC (analog weather charts) method onto the high-precision GPV-MSM (Grid Point Value of Meso-Scale Model) water-vapor data to find the latter's matching meteorological data. From the selected JERS-1 interferometry pair and the matching GPV-MSM meteorological data, the atmospheric path delay generated by water vapor inhomogeneity was then quantitatively evaluated. A highly uniform spatial distribution of the atmospheric delay, with a maximum deviation of approximately 38 mm in its horizontal distribution was found over the Plain. This confirms the effectiveness of using GPV-MSM data for SAR differential interferometric analysis, and sheds thus some new light on the possibility of improving InSAR analysis results for land subsidence applications. PMID:24385028
12 CFR 21.11 - Suspicious Activity Report.
Code of Federal Regulations, 2011 CFR
2011-01-01
... Activity Report on the form prescribed by the OCC. (c) SARs required. A national bank shall file a SAR with... supervisory action. (j) Obtaining SARs. A national bank may obtain SARs and the Instructions from the appropriate OCC District Office listed in 12 CFR part 4. (k) Confidentiality of SARs. SARs are confidential...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Simmons, Graham, E-mail: gsimmons@bloodsystems.or; Bertram, Stephanie; Glowacka, Ilona
Severe acute respiratory syndrome coronavirus (SARS-CoV) poses a considerable threat to human health. Activation of the viral spike (S)-protein by host cell proteases is essential for viral infectivity. However, the cleavage sites in SARS-S and the protease(s) activating SARS-S are incompletely defined. We found that R667 was dispensable for SARS-S-driven virus-cell fusion and for SARS-S-activation by trypsin and cathepsin L in a virus-virus fusion assay. Mutation T760R, which optimizes the minimal furin consensus motif 758-RXXR-762, and furin overexpression augmented SARS-S activity, but did not result in detectable SARS-S cleavage. Finally, SARS-S-driven cell-cell fusion was independent of cathepsin L, a proteasemore » essential for virus-cell fusion. Instead, a so far unknown leupeptin-sensitive host cell protease activated cellular SARS-S for fusion with target cells expressing high levels of ACE2. Thus, different host cell proteases activate SARS-S for virus-cell and cell-cell fusion and SARS-S cleavage at R667 and 758-RXXR-762 can be dispensable for SARS-S activation.« less
12 CFR 208.62 - Suspicious activity reports.
Code of Federal Regulations, 2011 CFR
2011-01-01
.... (c) SARs required. A member bank shall file a SAR with the appropriate Federal law enforcement... SARs. SARs are confidential. Any member bank subpoenaed or otherwise requested to disclose a SAR or the...
12 CFR 208.62 - Suspicious activity reports.
Code of Federal Regulations, 2012 CFR
2012-01-01
.... (c) SARs required. A member bank shall file a SAR with the appropriate Federal law enforcement... SARs. SARs are confidential. Any member bank subpoenaed or otherwise requested to disclose a SAR or the...
Investigation of Lithospheric Structure in Mongolia: Insights from Insar Observations and Modelling
NASA Astrophysics Data System (ADS)
Jing, Z.; Bihong, F.; Pilong, S.; Qiang, G.
2017-09-01
The western Mongolia is a seismically active intracontinental region, with ongoing tectonic deformation and widespread seismicity related to the far-field effects of India-Eurasia collision. During the 20th century, four earthquakes with the magnitude larger than 8 occurred in the western Mongolia and its surrounding regions, providing a unique opportunity to study the geodynamics of intracontinental tectonic deformations. The 1957 magnitude 8.3 Gobi-Altai earthquake is one of the largest seismic events. The deformation pattern of rupture zone associated with this earthquake is complex, involving left-lateral strike-slip and reverse dip-slip faulting on several distinct geological structures in a 264 × 40 km wide zone. To understand the relationship between the observed postseismic surface deformation and the rheological structure of the upper lithosphere, Interferometric Synthetic Aperture Radar (InSAR) data are used to study the 1957 earthquake. Then we developed a postseismic model in a spherical, radially layered elastic-viscoelastic Earth based on InSAR results, and further analysed the dominant contribution to the surface deformation. This work is important for understanding not only the regional tectonics, but also the structure and dynamics of the lithosphere. SAR data were acquired from the ERS1/2 and Envisat from 1996 to 2010. Using the Repeat Orbit Interferometry Package (ROI_PAC), 124 postseismic interferograms are produced on four adjacent tracks. By stacking these interferograms, the maximum InSAR line-of-sight deformation rate along the Gobi-Altai fault zone is obtained. The main results are as follows: (1) The maximum InSAR line-of-sight deformation velocity along this large fault zone is about 6 mm/yr; (2) The modelled surface deformation suggests that the viscoelastic relaxation is the most reasonable mechanism to explain the observed surface motion; (3) The optimal model cover the Gobi-Altai seismogenic thickness is 10 km; (4) The lower bound of Maxwell viscosity of lower crust and upper mantle is approximately 9 × 1019 Pa s, and the Maxwell relaxation time corresponding to this viscosity is 95.13 years.
NASA Astrophysics Data System (ADS)
Xu, Guangyu; Xu, Caijun; Wen, Yangmao
2018-04-01
New satellites are now revealing InSAR-based surface deformation within a week after natural hazard events. Quick hazard responses will be more publically accessible and provide information to responding agencies. Here we used Sentinel-1 interferometric synthetic aperture radar (InSAR) data to investigate coseismic deformation associated with the 2017 Sangsefid earthquake, which occurred in the southeast margin of the Kopeh Dagh fault system. The ascending and descending interferograms indicate thrust-dominated slip, with the maximum line-of-sight displacement of 10.5 and 13.7 cm, respectively. The detailed slip-distribution of the 2017 Sangsefid Mw6.1 earthquake inferred from geodetic data is presented here for the first time. Although the InSAR interferograms themselves do not uniquely constrain what the primary slip surface is, we infer that the source fault dips to southwest by analyzing the 2.5 D displacement field decomposed from the InSAR observations. The determined uniform slip fault model shows that the dip angle of the seimogenic fault is approximately 40°, with a strike of 120° except for a narrower fault width than that predicted by the empirical scaling law. We suggest that geometric complexities near the Kopeh Dagh fault system obstruct the rupture propagation, resulting in high slip occurred within a small area and much higher stress drop than global estimates. The InSAR-determined moment is 1.71 × 1018 Nm with a shear modulus of 3.32 × 1010 N/m2, equivalent to Mw 6.12, which is consistent with seismological results. The finite fault model (the west-dipping fault plane) reveals that the peak slip of 0.90 m occurred at a depth of 6.3 km, with substantial slip at a depth of 4-10 km and a near-uniform slip of 0.1 m at a depth of 0-2.5 km. We suggest that the Sangsefid earthquake occurred on an unknown blind reverse fault dipping southwest, which can also be recognised through observing the long-term surface effects due to the existence of the blind fault.
Combined DEM Extration Method from StereoSAR and InSAR
NASA Astrophysics Data System (ADS)
Zhao, Z.; Zhang, J. X.; Duan, M. Y.; Huang, G. M.; Yang, S. C.
2015-06-01
A pair of SAR images acquired from different positions can be used to generate digital elevation model (DEM). Two techniques exploiting this characteristic have been introduced: stereo SAR and interferometric SAR. They permit to recover the third dimension (topography) and, at the same time, to identify the absolute position (geolocation) of pixels included in the imaged area, thus allowing the generation of DEMs. In this paper, StereoSAR and InSAR combined adjustment model are constructed, and unify DEM extraction from InSAR and StereoSAR into the same coordinate system, and then improve three dimensional positioning accuracy of the target. We assume that there are four images 1, 2, 3 and 4. One pair of SAR images 1,2 meet the required conditions for InSAR technology, while the other pair of SAR images 3,4 can form stereo image pairs. The phase model is based on InSAR rigorous imaging geometric model. The master image 1 and the slave image 2 will be used in InSAR processing, but the slave image 2 is only used in the course of establishment, and the pixels of the slave image 2 are relevant to the corresponding pixels of the master image 1 through image coregistration coefficient, and it calculates the corresponding phase. It doesn't require the slave image in the construction of the phase model. In Range-Doppler (RD) model, the range equation and Doppler equation are a function of target geolocation, while in the phase equation, the phase is also a function of target geolocation. We exploit combined adjustment model to deviation of target geolocation, thus the problem of target solution is changed to solve three unkonwns through seven equations. The model was tested for DEM extraction under spaceborne InSAR and StereoSAR data and compared with InSAR and StereoSAR methods respectively. The results showed that the model delivered a better performance on experimental imagery and can be used for DEM extraction applications.
NASA Astrophysics Data System (ADS)
de Michele, M.; Raucoules, D.; Rohmer, J.; Loschetter, A.; Raffard, D.; Le Gallo, Y.
2013-12-01
A prerequisite to the large scale industrial development of CO2 Capture and geological Storage is the demonstration that the storage is both efficient and safe. In this context, precise uplift/subsidence monitoring techniques constitute a key component of any CO2 storage risk management. Space-borne Differential SAR (Synthetic Aperture Radar) interferometry is a promising monitoring technique. It can provide valuable information on vertical positions of a set of scatterer undergoing surface deformation induced by volumetric changes through time and space caused by CO2 injection in deep aquifers. To what extent ? To date, InSAR techniques have been successfully used in a variety of case-studies involving the measure of surface deformation caused by subsurface fluid withdrawal / injection. For instance, groundwater flow characterization in complex aquifers systems, oil / gas field characterization, verification of enhanced oil recovery efficiency, monitoring of seasonal gas storage. The successful use of InSAR is strictly related to the favourable scattering conditions in terms of spatial distribution of targets and their temporal stability. In arid regions, natural radar scatterers density can be very high, exceeding 1,000 per square km. But future onshore industrial-scale CO2 storage sites are planned in more complex land-covers such as agricultural or vegetated terrains. Those terrains are characterized by poor to moderate radar scatterers density, which decrease the detection limits of the space-borne interferometric technique. The present study discusses the limits and constraints of advanced InSAR techniques applied to deformation measurements associated with CO2 injection/storage into deep aquifers in the presence of agricultural and vegetated land-covers. We explore different options to enhance the measurement performances of InSAR techniques. As a first option, we propose to optimize the deployment of a network of 'artificial' scatterers, i.e. corner reflectors (artificial devices installed on ground to provide high backscatter to the radar signal) to complement the existing 'natural' network. The methodology is iterative and adaptive to the spatial and temporal extent of the detectable deforming region. We take into account the need of a change in sensors characteristics (for a very long term monitoring 10-50 years) that could result in a need of re-organisation of the network. Our discussion is supported by the estimates of the expected spatio-temporal evolution of surface vertical displacements caused by CO2 injection at depth by combining the approximate analytical solutions for pressure build-up during CO2 injection in deep aquifers and the poro-elastic behaviour of the reservoir under injection. As second option, we then review different advanced InSAR algorithms that could improve the displacement measurements using natural scatterers over vegetated areas.
Space Radar Image of Mammoth, California
NASA Technical Reports Server (NTRS)
1999-01-01
This image is a false-color composite of the Mammoth Mountain area in the Sierra Nevada Mountains, California. The image is centered at 37.6 degrees north latitude and 119.0 degrees west longitude. The area is approximately 11.5 kilometers by 78.3 kilometers (7.2 by 48.7 miles) in size. The image was acquired by the Spaceborne Imaging Radar-C and X-Synthetic Aperture Radar (SIR-C/X-SAR) aboard space shuttle Endeavour on its 40th orbit, April 11, 1994. The city of Mammoth Lakes is visible in the bottom right portion of the scene. In this color representation, red is C-band HV-polarization, green is C-band VV-polarization and blue is the ratio of C-band VV to C-band HV. Blue areas are lakes or slopes facing away from the radar illumination. Yellow represents areas of dry, old snow as well as slopes facing directly the radar illumination. At the time of the SIR-C overflight, the sky conditions were partially cloudy, with low and cold air temperatures. Total snow depth is about 1 to 1.5 meters (3 to 5 feet). The current snow accumulation is only about 40 percent of the average for the season. The most recent snowfall in the area covered the entire area with about 30 centimeters (14 inches) of fresh dry snow. Above 3,000 meters (10,000 feet) elevation the snowpack is dry. Below that elevation, the snowpack has a layered structure. Snow hydrologists are using SIR-C/X-SAR data to determine both the quantity of water held by seasonal snowpack and the amount of snow melting. SIR-C/X-SAR radars illuminate Earth with microwaves allowing detailed observations at any time, regardless of weather or sunlight conditions. SIR-C/X-SAR uses three microwave wavelengths: L-band (24 cm), C-band (6 cm)and X-band (3 cm). The multi-frequency data will be used by the international scientific community to better understand the global environment and how it is changing. The SIR-C/X-SAR data, in conjunction with aircraft and ground studies, will give scientists clearer insights into those environmental changes which are caused by nature and those changes which are induced by human activity. SIR-C was developed by NASA's Jet Propulsion Laboratory. X-SAR was developed by the Dornier and Alenia Spazio companies for the German space agency, Deutsche Agentur fuer Raumfahrtangelegenheiten (DARA), and the Italian space agency, Agenzia Spaziale Italiana (ASI) with the Deutsche Forschungsanstalt fur Luft und Raumfahrt e.v. (DLR), the major partner in science, operation and data processing of X-SAR.
Bertram, Stephanie; Glowacka, Ilona; Müller, Marcel A.; Lavender, Hayley; Gnirss, Kerstin; Nehlmeier, Inga; Niemeyer, Daniela; He, Yuxian; Simmons, Graham; Drosten, Christian; Soilleux, Elizabeth J.; Jahn, Olaf; Steffen, Imke; Pöhlmann, Stefan
2011-01-01
The highly pathogenic severe acute respiratory syndrome coronavirus (SARS-CoV) poses a constant threat to human health. The viral spike protein (SARS-S) mediates host cell entry and is a potential target for antiviral intervention. Activation of SARS-S by host cell proteases is essential for SARS-CoV infectivity but remains incompletely understood. Here, we analyzed the role of the type II transmembrane serine proteases (TTSPs) human airway trypsin-like protease (HAT) and transmembrane protease, serine 2 (TMPRSS2), in SARS-S activation. We found that HAT activates SARS-S in the context of surrogate systems and authentic SARS-CoV infection and is coexpressed with the viral receptor angiotensin-converting enzyme 2 (ACE2) in bronchial epithelial cells and pneumocytes. HAT cleaved SARS-S at R667, as determined by mutagenesis and mass spectrometry, and activated SARS-S for cell-cell fusion in cis and trans, while the related pulmonary protease TMPRSS2 cleaved SARS-S at multiple sites and activated SARS-S only in trans. However, TMPRSS2 but not HAT expression rendered SARS-S-driven virus-cell fusion independent of cathepsin activity, indicating that HAT and TMPRSS2 activate SARS-S differentially. Collectively, our results show that HAT cleaves and activates SARS-S and might support viral spread in patients. PMID:21994442
UAVSAR Active Electronically-Scanned Array
NASA Technical Reports Server (NTRS)
Sadowy, Gregory; Brown, Kyle; Chamberlain, Neil; Figueroa, Harry; Fisher, Charlie; Grando, Maurio; Hamilton, Gary; Vorperian, Vatche; Zawadzki, Mark
2010-01-01
The Uninhabited Airborne Vehicle Synthetic Aperture Radar (UAVSAR) L-band (1.2-1.3 GHz) repeat pass, interferometric synthetic aperture radar (InSAR) used for Earth science applications. Using complex radar images collected during separate passes on time scales of hours to years, changes in surface topography can be measured. The repeat-pass InSAR technique requires that the radar look angle be approximately the same on successive passes. Due to variations in aircraft attitude between passes, antenna beam steering is required to replicate the radar look angle. This paper describes an active, electronically steered array (AESA) that provides beam steering capability in the antenna azimuth plane. The array contains 24 transmit/receive modules generating 2800 W of radiated power and is capable of pulse-to-pulse beam steering and polarization agility. Designed for high reliability as well as serviceability, all array electronics are contained in single 178cm x 62cm x 12 cm air-cooled panel suitable for operation up 60,000 ft altitude.
Grid infrastructure for automatic processing of SAR data for flood applications
NASA Astrophysics Data System (ADS)
Kussul, Natalia; Skakun, Serhiy; Shelestov, Andrii
2010-05-01
More and more geosciences applications are being put on to the Grids. Due to the complexity of geosciences applications that is caused by complex workflow, the use of computationally intensive environmental models, the need of management and integration of heterogeneous data sets, Grid offers solutions to tackle these problems. Many geosciences applications, especially those related to the disaster management and mitigations require the geospatial services to be delivered in proper time. For example, information on flooded areas should be provided to corresponding organizations (local authorities, civil protection agencies, UN agencies etc.) no more than in 24 h to be able to effectively allocate resources required to mitigate the disaster. Therefore, providing infrastructure and services that will enable automatic generation of products based on the integration of heterogeneous data represents the tasks of great importance. In this paper we present Grid infrastructure for automatic processing of synthetic-aperture radar (SAR) satellite images to derive flood products. In particular, we use SAR data acquired by ESA's ENVSAT satellite, and neural networks to derive flood extent. The data are provided in operational mode from ESA rolling archive (within ESA Category-1 grant). We developed a portal that is based on OpenLayers frameworks and provides access point to the developed services. Through the portal the user can define geographical region and search for the required data. Upon selection of data sets a workflow is automatically generated and executed on the resources of Grid infrastructure. For workflow execution and management we use Karajan language. The workflow of SAR data processing consists of the following steps: image calibration, image orthorectification, image processing with neural networks, topographic effects removal, geocoding and transformation to lat/long projection, and visualisation. These steps are executed by different software, and can be executed by different resources of the Grid system. The resulting geospatial services are available in various OGC standards such as KML and WMS. Currently, the Grid infrastructure integrates the resources of several geographically distributed organizations, in particular: Space Research Institute NASU-NSAU (Ukraine) with deployed computational and storage nodes based on Globus Toolkit 4 (htpp://www.globus.org) and gLite 3 (http://glite.web.cern.ch) middleware, access to geospatial data and a Grid portal; Institute of Cybernetics of NASU (Ukraine) with deployed computational and storage nodes (SCIT-1/2/3 clusters) based on Globus Toolkit 4 middleware and access to computational resources (approximately 500 processors); Center of Earth Observation and Digital Earth Chinese Academy of Sciences (CEODE-CAS, China) with deployed computational nodes based on Globus Toolkit 4 middleware and access to geospatial data (approximately 16 processors). We are currently adding new geospatial services based on optical satellite data, namely MODIS. This work is carried out jointly with the CEODE-CAS. Using workflow patterns that were developed for SAR data processing we are building new workflows for optical data processing.
Exposure to vinyl chloride and angiosarcoma of the liver: a report of the register of cases.
Forman, D; Bennett, B; Stafford, J; Doll, R
1985-11-01
The Association of Plastic Manufacturers in Europe maintains a register of all cases of angiosarcoma of the liver (ASL) resulting from exposure to vinyl chloride monomer (VCM). This register has recorded all known VCM related cases of the disease worldwide that have been histologically confirmed. Although likely to be incomplete, it is the most comprehensive tabulation of such cases available and, by the end of 1984, 118 men had been registered. The information from analysis of the cases currently on the register is used to make an approximate projection of the number of cases to be expected in the future. The conclusion from this projection is that the industry is reaching the halfway stage in the appearance of VCM related ASL.
Exposure to vinyl chloride and angiosarcoma of the liver: a report of the register of cases.
Forman, D; Bennett, B; Stafford, J; Doll, R
1985-01-01
The Association of Plastic Manufacturers in Europe maintains a register of all cases of angiosarcoma of the liver (ASL) resulting from exposure to vinyl chloride monomer (VCM). This register has recorded all known VCM related cases of the disease worldwide that have been histologically confirmed. Although likely to be incomplete, it is the most comprehensive tabulation of such cases available and, by the end of 1984, 118 men had been registered. The information from analysis of the cases currently on the register is used to make an approximate projection of the number of cases to be expected in the future. The conclusion from this projection is that the industry is reaching the halfway stage in the appearance of VCM related ASL. PMID:4063218
Cameron, Mark J; Kelvin, Alyson A; Leon, Alberto J; Cameron, Cheryl M; Ran, Longsi; Xu, Luoling; Chu, Yong-Kyu; Danesh, Ali; Fang, Yuan; Li, Qianjun; Anderson, Austin; Couch, Ronald C; Paquette, Stephane G; Fomukong, Ndingsa G; Kistner, Otfried; Lauchart, Manfred; Rowe, Thomas; Harrod, Kevin S; Jonsson, Colleen B; Kelvin, David J
2012-01-01
In terms of its highly pathogenic nature, there remains a significant need to further define the immune pathology of SARS-coronavirus (SARS-CoV) infection, as well as identify correlates of immunity to help develop vaccines for severe coronaviral infections. Here we use a SARS-CoV infection-reinfection ferret model and a functional genomics approach to gain insight into SARS immunopathogenesis and to identify correlates of immune protection during SARS-CoV-challenge in ferrets previously infected with SARS-CoV or immunized with a SARS virus vaccine. We identified gene expression signatures in the lungs of ferrets associated with primary immune responses to SARS-CoV infection and in ferrets that received an identical second inoculum. Acute SARS-CoV infection prompted coordinated innate immune responses that were dominated by antiviral IFN response gene (IRG) expression. Reinfected ferrets, however, lacked the integrated expression of IRGs that was prevalent during acute infection. The expression of specific IRGs was also absent upon challenge in ferrets immunized with an inactivated, Al(OH)(3)-adjuvanted whole virus SARS vaccine candidate that protected them against SARS-CoV infection in the lungs. Lack of IFN-mediated immune enhancement in infected ferrets that were previously inoculated with, or vaccinated against, SARS-CoV revealed 9 IRG correlates of protective immunity. This data provides insight into the molecular pathogenesis of SARS-CoV and SARS-like-CoV infections and is an important resource for the development of CoV antiviral therapeutics and vaccines.
Serology of severe acute respiratory syndrome: implications for surveillance and outcome.
Chen, Xinchun; Zhou, Boping; Li, Meizhong; Liang, Xiaorong; Wang, Huosheng; Yang, Guilin; Wang, Hui; Le, Xiaohua
2004-04-01
Severe acute respiratory syndrome (SARS) is a novel infectious disease. No information is currently available on host-specific immunity against the SARS coronavirus (CoV), and detailed characteristics of the epidemiology of SARS CoV infection have not been identified. ELISA was used to detect antibody to SARS CoV. Reverse-transcriptase polymerase chain reaction was used to detect SARS CoV RNA. T cells in peripheral blood of patients were quantified by flow cytometry. Of 36 patients with probable SARS CoV infection, 30 (83.3%) were positive for IgG antibody to SARS CoV; in contrast, only 3 of 48 patients with suspected SARS CoV infection, 0 of 112 patients with fever but without SARS, and 0 of 96 healthy control individuals were positive for it. IgG antibody to SARS CoV was first detected between day 5 and day 47 after onset of illness (mean +/- SD, 18.7+/-10.4). Detection of antibody to SARS CoV is useful in the diagnosis of SARS; however, at the incubation and initial phases of the illness, serological assay is of little value, because of late seroconversion in most patients.
Statistical properties of superactive regions during solar cycles 19-23
NASA Astrophysics Data System (ADS)
Chen, A. Q.; Wang, J. X.; Li, J. W.; Feynman, J.; Zhang, J.
2011-10-01
Context. Each solar activity cycle is characterized by a small number of superactive regions (SARs) that produce the most violent of space weather events with the greatest disastrous influence on our living environment. Aims: We aim to re-parameterize the SARs and study the latitudinal and longitudinal distributions of SARs. Methods: We select 45 SARs in solar cycles 21-23, according to the following four parameters: 1) the maximum area of sunspot group, 2) the soft X-ray flare index, 3) the 10.7 cm radio peak flux, and 4) the variation in the total solar irradiance. Another 120 SARs given by previous studies of solar cycles 19-23 are also included. The latitudinal and longitudinal distributions of the 165 SARs in both the Carrington frame and the dynamic reference frame during solar cycles 19-23 are studied statistically. Results: Our results indicate that these 45 SARs produced 44% of all the X class X-ray flares during solar cycles 21-23, and that all the SARs are likely to produce a very fast CME. The latitudinal distributions of SARs display the Maunder butterfly diagrams and SARs occur preferentially in the maximum period of each solar cycle. Northern hemisphere SARs dominated in solar cycles 19 and 20 and southern hemisphere SARs dominated in solar cycles 21 and 22. In solar cycle 23, however, SARs occurred about equally in each hemisphere. There are two active longitudes in both the northern and southern hemispheres, about 160°-200° apart. Applying the improved dynamic reference frame to SARs, we find that SARs rotate faster than the Carrington rate and there is no significant difference between the two hemispheres. The synodic periods are 27.19 days and 27.25 days for the northern and southern hemispheres, respectively. The longitudinal distribution of SARs is significantly non-axisymmetric and about 75% SARs occurred near two active longitudes with half widths of 45°. Appendix A is available in electronic form at http://www.aanda.org
Creating a national register of childhood type 1 diabetes using routinely collected hospital data.
Hodgson, Susan; Beale, Linda; Parslow, Roger C; Feltbower, Richard G; Jarup, Lars
2012-05-01
There is no national register of childhood type 1 diabetes mellitus for England. Our aim was to assess the feasibility of using routine hospital admissions data as a surrogate for a childhood diabetes register across England, and to create a geographically referenced childhood diabetes dataset for use in epidemiologic studies and health service research. Hospital Episodes Statistics data for England from April 1992 to March 2006 referring to a type 1 diabetes diagnosis in 0-14 yr olds were cleaned to approximate an incident dataset. The cleaned data were validated against regional population-based register data, available for Yorkshire and the area of the former Oxford Regional Health Authority. There were 32 665 unique cases of type 1 and type unknown diabetes over the study period. The hospital-derived data improved in quality over time (91% concordance with regional register data over the period 2000-2006 vs. 52% concordance over the period 1992-1999), and data quality was better for younger (0-9 yr) (86.5% concordance with regional register data) than older cases (10-14 yr). Overall incidence was 24.99 (95% confidence interval 24.71-25.26) per 100 000. Basic trends in age distribution, seasonality of onset, and incidence matched well with previously reported findings. We were able to create a surrogate register of childhood diabetes based on national hospital admissions data, containing approximately 2300 cases/yr, and geo-coded to a high resolution. For younger cases (0-9 yr) and more recent years (from 2000) these data will be a useful resource for epidemiological studies exploring the determinants of childhood diabetes. © 2011 John Wiley & Sons A/S.
Flood extent and water level estimation from SAR using data-model integration
NASA Astrophysics Data System (ADS)
Ajadi, O. A.; Meyer, F. J.
2017-12-01
Synthetic Aperture Radar (SAR) images have long been recognized as a valuable data source for flood mapping. Compared to other sources, SAR's weather and illumination independence and large area coverage at high spatial resolution supports reliable, frequent, and detailed observations of developing flood events. Accordingly, SAR has the potential to greatly aid in the near real-time monitoring of natural hazards, such as flood detection, if combined with automated image processing. This research works towards increasing the reliability and temporal sampling of SAR-derived flood hazard information by integrating information from multiple SAR sensors and SAR modalities (images and Interferometric SAR (InSAR) coherence) and by combining SAR-derived change detection information with hydrologic and hydraulic flood forecast models. First, the combination of multi-temporal SAR intensity images and coherence information for generating flood extent maps is introduced. The application of least-squares estimation integrates flood information from multiple SAR sensors, thus increasing the temporal sampling. SAR-based flood extent information will be combined with a Digital Elevation Model (DEM) to reduce false alarms and to estimate water depth and flood volume. The SAR-based flood extent map is assimilated into the Hydrologic Engineering Center River Analysis System (Hec-RAS) model to aid in hydraulic model calibration. The developed technology is improving the accuracy of flood information by exploiting information from data and models. It also provides enhanced flood information to decision-makers supporting the response to flood extent and improving emergency relief efforts.
Memory T cell responses targeting the SARS coronavirus persist up to 11 years post-infection.
Ng, Oi-Wing; Chia, Adeline; Tan, Anthony T; Jadi, Ramesh S; Leong, Hoe Nam; Bertoletti, Antonio; Tan, Yee-Joo
2016-04-12
Severe acute respiratory syndrome (SARS) is a highly contagious infectious disease which first emerged in late 2002, caused by a then novel human coronavirus, SARS coronavirus (SARS-CoV). The virus is believed to have originated from bats and transmitted to human through intermediate animals such as civet cats. The re-emergence of SARS-CoV remains a valid concern due to the continual persistence of zoonotic SARS-CoVs and SARS-like CoVs (SL-CoVs) in bat reservoirs. In this study, the screening for the presence of SARS-specific T cells in a cohort of three SARS-recovered individuals at 9 and 11 years post-infection was carried out, and all memory T cell responses detected target the SARS-CoV structural proteins. Two CD8(+) T cell responses targeting the SARS-CoV membrane (M) and nucleocapsid (N) proteins were characterized by determining their HLA restriction and minimal T cell epitope regions. Furthermore, these responses were found to persist up to 11 years post-infection. An absence of cross-reactivity of these CD8(+) T cell responses against the newly-emerged Middle East respiratory syndrome coronavirus (MERS-CoV) was also demonstrated. The knowledge of the persistence of SARS-specific celullar immunity targeting the viral structural proteins in SARS-recovered individuals is important in the design and development of SARS vaccines, which are currently unavailable. Copyright © 2016 Elsevier Ltd. All rights reserved.
Local SAR in Parallel Transmission Pulse Design
Lee, Joonsung; Gebhardt, Matthias; Wald, Lawrence L.; Adalsteinsson, Elfar
2011-01-01
The management of local and global power deposition in human subjects (Specific Absorption Rate, SAR) is a fundamental constraint to the application of parallel transmission (pTx) systems. Even though the pTx and single channel have to meet the same SAR requirements, the complex behavior of the spatial distribution of local SAR for transmission arrays poses problems that are not encountered in conventional single-channel systems and places additional requirements on pTx RF pulse design. We propose a pTx pulse design method which builds on recent work to capture the spatial distribution of local SAR in numerical tissue models in a compressed parameterization in order to incorporate local SAR constraints within computation times that accommodate pTx pulse design during an in vivo MRI scan. Additionally, the algorithm yields a Protocol-specific Ultimate Peak in Local SAR (PUPiL SAR), which is shown to bound the achievable peak local SAR for a given excitation profile fidelity. The performance of the approach was demonstrated using a numerical human head model and a 7T eight-channel transmit array. The method reduced peak local 10g SAR by 14–66% for slice-selective pTx excitations and 2D selective pTx excitations compared to a pTx pulse design constrained only by global SAR. The primary tradeoff incurred for reducing peak local SAR was an increase in global SAR, up to 34% for the evaluated examples, which is favorable in cases where local SAR constraints dominate the pulse applications. PMID:22083594
Adaptation of existing infrared technologies to unanticipated applications
NASA Astrophysics Data System (ADS)
Peng, Philip
2005-01-01
Radiation thermometry is just but one of many applications, both potential and realized, of infrared technology. During the SARS (Severe Acute Respiratory Syndromes) global crisis in 2003, the technology was utilized as a preliminary screening method for infected persons as a defense against a major outbreak, as the primary symptom of this disease is elevated body temperature. ATC timely developed a product designed specifically for mass volume crowd screening of febrile individuals. For this application, the machine must register temperature of subjects rapidly and efficiently, with a certain degree of accuracy, and function for extended periods of time. The equipment must be safe to use, easily deployed, and function with minimum maintenance needed. The ATIR-303 model satisfies all of the above and other pre-requisite conditions amicably. Studies on the correlation between the maximum temperature registered among individual's facial features, as measured under the conditions of usage, and the core temperature of individuals were performed. The results demonstrated that ATIR-303 is very suitable for this application. Other applications of the infrared technology in various areas, like medical diagnosis, non-destructive testing, security, search and rescue, and others, are also interest areas of ATC. The progress ATC has achieved in these areas is presented also.
ERIC Educational Resources Information Center
Gilpatrick, Eleanor
To secure information about the characteristics of the practical nurse population and their opinions about registered nurse preparation, questionnaires were distributed to 2,923 practical nurses employed by the New York City Municipal Hospitals. Usable questionnaires numbered 2,361 or 81 percent of the employed PN population. Approximately 9…
NASA Technical Reports Server (NTRS)
Wu, S. T.
1983-01-01
Data acquired by synthetic aperture radar (SAR) and LANDSAT multispectral scanner (MSS) were processed and analyzed to derive forest-related resources inventory information. The SAR data were acquired by using the NASA aircraft X-band SAR with linear (HH, VV) and cross (HV, VH) polarizations and the SEASAT L-band SAR. After data processing and data quality examination, the three polarization (HH, HV, and VV) data from the aircraft X-band SAR were used in conjunction with LANDSAT MSS for multisensor data classification. The results of accuracy evaluation for the SAR, MSS and SAR/MSS data using supervised classification show that the SAR-only data set contains low classification accuracy for several land cover classes. However, the SAR/MSS data show that significant improvement in classification accuracy is obtained for all eight land cover classes. These results suggest the usefulness of using combined SAR/MSS data for forest-related cover mapping. The SAR data also detect several small special surface features that are not detectable by MSS data.
Regla-Nava, Jose A.; Jimenez-Guardeño, Jose M.; Nieto-Torres, Jose L.; Gallagher, Thomas M.; Enjuanes, Luis; DeDiego, Marta L.
2013-01-01
Infection of conventional mice with a mouse adapted (MA15) severe acute respiratory syndrome (SARS) coronavirus (CoV) reproduces many aspects of human SARS such as pathological changes in lung, viremia, neutrophilia, and lethality. However, established mouse cell lines highly susceptible to mouse-adapted SARS-CoV infection are not available. In this work, efficiently transfectable mouse cell lines stably expressing the murine SARS-CoV receptor angiotensin converting enzyme 2 (ACE2) have been generated. These cells yielded high SARS-CoV-MA15 titers and also served as excellent tools for plaque assays. In addition, in these cell lines, SARS-CoV-MA15 induced the expression of proinflammatory cytokines and IFN-β, mimicking what has been observed in experimental animal models infected with SARS-CoV and SARS patients. These cell lines are valuable tools to perform in vitro studies in a mouse cell system that reflects the species used for in vivo studies of SARS-CoV-MA15 pathogenesis. PMID:23911968
Mathematical modeling and SAR simulation multifunction SAR technology efforts
NASA Technical Reports Server (NTRS)
Griffin, C. R.; Estes, J. M.
1981-01-01
The orbital SAR (synthetic aperture radar) simulation data was used in several simulation efforts directed toward advanced SAR development. Efforts toward simulating an operational radar, simulation of antenna polarization effects, and simulation of SAR images at serveral different wavelengths are discussed. Avenues for improvements in the orbital SAR simulation and its application to the development of advanced digital radar data processing schemes are indicated.
Deng, J-F; Olowokure, B; Kaydos-Daniels, S C; Chang, H-J; Barwick, R S; Lee, M-L; Deng, C-Y; Factor, S H; Chiang, C-E; Maloney, S A
2006-01-01
In June 2003, Taiwan introduced a severe acute respiratory syndrome (SARS) telephone hotline service to provide concerned callers with rapid access to information, advice and appropriate referral where necessary. This paper reports an evaluation of the knowledge, attitude, practices and sources of information relating to SARS among physicians who staffed the SARS fever hotline service. A retrospective survey was conducted using a self-administered postal questionnaire. Participants were physicians who staffed a SARS hotline during the SARS epidemic in Taipei, Taiwan from June 1 to 10, 2003. A response rate of 83% was obtained. All respondents knew the causative agent of SARS, and knowledge regarding SARS features and preventive practices was good. However, only 54% of respondents knew the incubation period of SARS. Hospital guidelines and news media were the major information sources. In responding to two case scenarios most physicians were likely to triage callers at high risk of SARS appropriately, but not callers at low risk. Less than half of all respondents answered both scenarios correctly. The results obtained suggest that knowledge of SARS was generally good although obtained from both medical and non-medical sources. Specific knowledge was however lacking in certain areas and this affected the ability to appropriately triage callers. Standardized education and assessment of prior knowledge of SARS could improve the ability of physicians to triage callers in future outbreaks.
Mitigating illumination gradients in a SAR image based on the image data and antenna beam pattern
Doerry, Armin W.
2013-04-30
Illumination gradients in a synthetic aperture radar (SAR) image of a target can be mitigated by determining a correction for pixel values associated with the SAR image. This correction is determined based on information indicative of a beam pattern used by a SAR antenna apparatus to illuminate the target, and also based on the pixel values associated with the SAR image. The correction is applied to the pixel values associated with the SAR image to produce corrected pixel values that define a corrected SAR image.
Evaluation of the operational SAR based Baltic sea ice concentration products
NASA Astrophysics Data System (ADS)
Karvonen, Juha
Sea ice concentration is an important ice parameter both for weather and climate modeling and sea ice navigation. We have developed an fully automated algorithm for sea ice concentration retrieval using dual-polarized ScanSAR wide mode RADARSAT-2 data. RADARSAT-2 is a C-band SAR instrument enabling dual-polarized acquisition in ScanSAR mode. The swath width for the RADARSAT-2 ScanSAR mode is about 500 km, making it very suitable for operational sea ice monitoring. The polarization combination used in our concentration estimation is HH/HV. The SAR data is first preprocessed, the preprocessing consists of geo-rectification to Mercator projection, incidence angle correction fro both the polarization channels. and SAR mosaicking. After preprocessing a segmentation is performed for the SAR mosaics, and some single-channel and dual-channel features are computed for each SAR segment. Finally the SAR concentration is estimated based on these segment-wise features. The algorithm is similar as introduced in Karvonen 2014. The ice concentration is computed daily using a daily RADARSAT-2 SAR mosaic as its input, and it thus gives the concentration estimated at each Baltic Sea location based on the most recent SAR data at the location. The algorithm has been run in an operational test mode since January 2014. We present evaluation of the SAR-based concentration estimates for the Baltic ice season 2014 by comparing the SAR results with gridded the Finnish Ice Service ice charts and ice concentration estimates from a radiometer algorithm (AMSR-2 Bootstrap algorithm results). References: J. Karvonen, Baltic Sea Ice Concentration Estimation Based on C-Band Dual-Polarized SAR Data, IEEE Transactions on Geoscience and Remote Sensing, in press, DOI: 10.1109/TGRS.2013.2290331, 2014.
Siu, Judy Yuen-Man
2016-06-01
Although SARS had been with a controversial topic for a decade at the time of this study, numerous SARS survivors had not yet physically, psychologically or socially recovered from the aftermath of SARS. Among chronically ill patients, the use of complementary and alternative medicine (CAM) is reported to be widespread. However, extremely little is known about the use of CAM by SARS survivors in the post-SARS period and even less is known about how the use of CAM is related to the unpleasant social and medical-treatment experiences of SARS survivors, their eagerness to re-establish social networks, and their awareness to prepare for future epidemics. To investigate the motivations for practising tai chi among SARS survivors in post-SARS Hong Kong. Using a qualitative approach, I conducted individual semi-structured interviews with 35 SARS survivors, who were purposively sampled from a tai chi class of a SARS-patient self-help group in Hong Kong. Health concerns and social experiences motivated the participants to practise tai chi in post-SARS Hong Kong. Experiencing health deterioration in relation to SARS-associated sequelae, coping with unpleasant experiences during follow-up biomedical treatments, a desire to regain an active role in recovery and rehabilitation, overcoming SARS-associated stigmas by establishing a new social network and preparing for potential future stigmatization and discrimination were the key motivators for them. The participants practised tai chi not only because they sought to improve their health but also because it provided a crucial social function and meaning to them. © 2014 John Wiley & Sons Ltd.
Gas-Phase Molecular Probe For High Throughput Screening
The U.S. EPA is responsible for evaluating the effects of approximately 80,000 chemicals registered for use in the USA. In addition, approximately 1,000 chemicals are added to this list each year. Due to the vast number of chemicals, it is impossible to conduct traditional toxi...
Synthetic Aperture Radar (SAR) data processing
NASA Technical Reports Server (NTRS)
Beckner, F. L.; Ahr, H. A.; Ausherman, D. A.; Cutrona, L. J.; Francisco, S.; Harrison, R. E.; Heuser, J. S.; Jordan, R. L.; Justus, J.; Manning, B.
1978-01-01
The available and optimal methods for generating SAR imagery for NASA applications were identified. The SAR image quality and data processing requirements associated with these applications were studied. Mathematical operations and algorithms required to process sensor data into SAR imagery were defined. The architecture of SAR image formation processors was discussed, and technology necessary to implement the SAR data processors used in both general purpose and dedicated imaging systems was addressed.
Space Radar Image of Colima Volcano, Jalisco, Mexico
NASA Technical Reports Server (NTRS)
1994-01-01
This is an image of the Colima volcano in Jalisco, Mexico, a vigorously active volcano that erupted as recently as July 1994. The eruption partially destroyed a lava dome at the summit and deposited a new layer of ash on the volcano's southern slopes. Surrounding communities face a continuing threat of ash falls and volcanic mudflows from the volcano, which has been designated one of 15 high-risk volcanoes for scientific study during the next decade. This image was acquired by the Spaceborne Imaging Radar-C and X-band Synthetic Aperture Radar (SIR-C/X-SAR) aboard the space shuttle Endeavour on its 24th orbit on October 1, 1994. The image is centered at 19.4 degrees north latitude, 103.7 degrees west longitude. The area shown is approximately 35.7 kilometers by 37.5 kilometers (22 miles by 23 miles). This single-frequency, multi-polarized SIR-C image shows: red as L-band horizontally transmitted and received; green as L-band horizontally transmitted and vertically received; and blue as the ratio of the two channels. The summit area appears orange and the recent deposits fill the valleys along the south and southwest slopes. Observations from space are helping scientists understand the behavior of dangerous volcanoes and will be used to mitigate the effects of future eruptions on surrounding populations. Spaceborne Imaging Radar-C and X-band Synthetic Aperture Radar (SIR-C/X-SAR) is part of NASA's Mission to Planet Earth. The radars illuminate Earth with microwaves, allowing detailed observations at any time, regardless of weather or sunlight conditions. SIR-C/X-SAR uses three microwave wavelengths: the L-band (24 cm), the C-band (6 cm) and the X-band (3 cm). The multi-frequency data will be used by the international scientific community to better understand the global environment and how it is changing. The SIR-C/X-SAR data, complemented by aircraft and ground studies, will give scientists clearer insights into those environmental changes which are caused by nature and those changes which are induced by human activity. SIR-C was developed by NASA's Jet Propulsion Laboratory. X-SAR was developed by the Dornier and Alenia Spazio companies for the German space agency, Deutsche Agentur fuer Raumfahrtangelegenheiten (DARA), and the Italian space agency, Agenzia Spaziale Italiana (ASI), with the Deutsche Forschungsanstalt fuer Luft und Raumfahrt e.V.(DLR), the major partner in science, operations and data processing of X-SAR.
Tsallis non-additive entropy and natural time analysis of seismicity
NASA Astrophysics Data System (ADS)
Sarlis, N. V.; Skordas, E. S.; Varotsos, P.
2017-12-01
Within the context of Tsallis non-additive entropy [1] statistical mechanics -in the frame of which kappa distributions arise [2,3]- a derivation of the Gutenberg-Richter (GR) law of seismicity has been proposed [4,5]. Such an analysis leads to a generalized GR law [6,7] which is applied here to the earthquakes in Japan and California. These seismic data are also studied in natural time [6] revealing that although some properties of seismicity may be recovered by the non-additive entropy approach, temporal correlations between successive earthquake magnitudes should be also taken into account [6,8]. The importance of such correlations is strengthened by the observation of periods of long range correlated earthquake magnitude time series [9] a few months before all earthquakes of magnitude 7.6 or larger in the entire Japanese area from 1 January 1984 to 11 March 2011 (the day of the magnitude 9.0 Tohoku-Oki earthquake) almost simultaneously with characteristic order parameter variations of seismicity [10]. These variations appear approximately when low frequency abnormal changes of the electric and magnetic field of the Earth (less than around 1Hz) are recorded [11] before strong earthquakes as the magnitude 9.0 Tohoku-Oki earthquake in Japan in 2011 [12]. 1. C Tsallis, J Stat Phys 52 (1988) 479 2. G Livadiotis, and D J McComas, J Geophys Res 114 (2009) A11105 3. G Livadiotis, Kappa Distributions. (Elsevier, Amsterdam) 2017. doi: 10.1016/B978-0-12-804638-8.01001-9 4. O Sotolongo-Costa, A Posadas, Phys Rev Lett 92 (2004) 048501 5. R Silva, G França, C Vilar, J Alcaniz, Phys Rev E 73 (2006) 026102 6. N Sarlis, E Skordas, P Varotsos, Phys Rev E 82 (2010) 021110 7. L Telesca, Bull Seismol Soc Am 102 (2012) 886-891 8. P Varotsos, N Sarlis, E Skordas, Natural Time Analysis: The new view of time. (Springer, Berlin) 2011. doi: 10.1007/978-3-642-16449-1 9. P Varotsos, N Sarlis, E Skordas, J Geophys Res Space Physics 119 (2014) 9192. 10. N Sarlis, E Skordas, P Varotsos, T Nagao, M Kamogawa, H Tanaka, S Uyeda, Proc Natl Acad Sci USA 110 (2013) 13734. 11. P Varotsos, N Sarlis, E Skordas, M Lazaridou-Varotsos, Earthq Sci 30 (2017) doi: 10.1007/s11589-017-0189-0 12. P Varotsos, N Sarlis, E Skordas, Earthq Sci 30 (2017) doi: 10.1007/s11589-017-0182-7
Elert, J; Kendall, S A; Larsson, B; Månsson, B; Gerdle, B
2001-06-01
To investigate if muscle tension according to the surface electromyogram (EMG) of the shoulder flexors is increased in consecutive patients with fibromyalgia (FM) or chronic whiplash associated disorders (WAD). A total of 59 consecutive patients with FM (n = 36) or chronic WAD (n = 23) performed 100 maximal isokinetic contractions combined with surface electromyography of the trapezius and infraspinatus. A randomized group of pain-free female (n = 27) subjects served as control group. Peak torque initially (Pti) and absolute and relative peak torque at endurance level (PTe, PTer) were registered as output variables, together with the EMG level of unnecessary muscle tension, i.e., the signal amplitude ratio (SAR). The patient groups had a higher level of unnecessary tension initially and at the endurance level. The patients had lower absolute output (PTi and PTe), but the relative levels (PTer) did not differ comparing all 3 groups. Subjects with FM had significantly higher body mass index (BMI) than the other groups. BMI did not influence the SAR but correlated positively with PTi. The results confirmed earlier findings that groups of patients with chronic pain have increased muscle tension and decreased output during dynamic activity compared to pain-free controls. However, the results indicated there is heterogeneity within groups of patients with the same chronic pain disorder and that not all patients with chronic pain have increased muscle tension.
NASA Astrophysics Data System (ADS)
Solaro, Giuseppe; Bonano, Manuela; Manzo, Mariarosaria
2016-04-01
The North Anatolian Fault (NAF) is one of the most active faults worldwide, extending approximately 1,200 km from Eastern Turkey to the Northern Aegean Sea. During the 20th century series of damaging earthquakes occurred along the NAF, generally propagated westward towards Istanbul; the last one occurred in 1999 at Izmit, a city 80 km away from Istanbul. Within this scenario, the FP7 MARsite project (New Directions in Seismic Hazard assessment through Focused Earth Observation in Marmara Supersite), supported by EU, intends to collect, share and integrate multidisciplinary data (seismologic, geochemical, surveying, satellite, etc.) in order to carry out assessment, mitigation and management of seismic risk in the region of the Sea of Marmara. In the framework of the MARsite project, we performed the analysis and monitoring of the surface deformation affecting the Istanbul mega city by exploiting the large archives of X-band satellite SAR data, made available through the Supersites Initiatives, and by processing them via the advanced multi-temporal and multi-scale InSAR technique, known as the Small BAseline Subset (SBAS) approach. In particular, we applied the SBAS technique to a dataset of 101 SAR images acquired by the TerraSAR-X constellation of the German Space Agency (DLR) over descending orbits and spanning the November 2010 - August 2014 time interval. From,these images, we generated 312 differential interferograms with a maximum spatial separation (perpendicular baseline) between the acquisition orbits of about 500 m., that were used to generate, via the SBAS approach, mean deformation velocity map and corresponding ground time series of the investigated area. The performed InSAR analysis reveals a generalized stability over the Istanbul area, except for some localized displacements, related to subsidence and slope instability phenomena. In particular, we identified: (i) a displacement pattern related to the Istanbul airport, showing a mostly linear deformation trend with a velocity of about 1 cm/yr, although a slowdown effect is observed starting from early 2014, and (ii) a subsidence phenomenon in correspondence to Miniaturk park with a mean velocity value of about 1.5 cm/yr. Moreover, by benefiting from the recent launch of the C-band Sentinel-1A (S1A) satellite (April 2014), developed within the European Commission Copernicus Programme, we performed a more recent InSAR analysis of the Istanbul mega city and its surroundings by exploiting datasets collected during the October 2014 - December 2015 time interval. In such a way, we are able to investigate possible changes in the spatial and temporal deformation rates of the detected displacements over time with the aim to improve the comprehension of the deformation processes already occurred and/or occurring in this area. The obtained results, generated within the MARsite project, are expected to be available to scientific community through the Geohazards Exploitation Platform (GEP), an ESA platform aimed at supporting the exploitation of satellite EO data for geohazards, to be fully compliant with some of the major issues of the Supersites Initiative, as well as to foster the InSAR data sharing within a wider scientific community.
12 CFR 390.355 - Suspicious Activity Reports and other reports and statements.
Code of Federal Regulations, 2012 CFR
2012-01-01
... Activity Report on the form prescribed by the FDIC. (3) SARs required. A State savings association shall... to supervisory action. (11) Obtaining SARs. A State savings association may obtain SARs and the... SARs. SARs are confidential. Any institution or person subpoenaed or otherwise requested to disclose a...
12 CFR 390.355 - Suspicious Activity Reports and other reports and statements.
Code of Federal Regulations, 2013 CFR
2013-01-01
... Activity Report on the form prescribed by the FDIC. (3) SARs required. A State savings association shall... to supervisory action. (11) Obtaining SARs. A State savings association may obtain SARs and the... SARs. SARs are confidential. Any institution or person subpoenaed or otherwise requested to disclose a...
12 CFR 390.355 - Suspicious Activity Reports and other reports and statements.
Code of Federal Regulations, 2014 CFR
2014-01-01
... Activity Report on the form prescribed by the FDIC. (3) SARs required. A State savings association shall... to supervisory action. (11) Obtaining SARs. A State savings association may obtain SARs and the... SARs. SARs are confidential. Any institution or person subpoenaed or otherwise requested to disclose a...
Regla-Nava, Jose A; Jimenez-Guardeño, Jose M; Nieto-Torres, Jose L; Gallagher, Thomas M; Enjuanes, Luis; DeDiego, Marta L
2013-11-01
Infection of conventional mice with a mouse adapted (MA15) severe acute respiratory syndrome (SARS) coronavirus (CoV) reproduces many aspects of human SARS such as pathological changes in lung, viremia, neutrophilia, and lethality. However, established mouse cell lines highly susceptible to mouse-adapted SARS-CoV infection are not available. In this work, efficiently transfectable mouse cell lines stably expressing the murine SARS-CoV receptor angiotensin converting enzyme 2 (ACE2) have been generated. These cells yielded high SARS-CoV-MA15 titers and also served as excellent tools for plaque assays. In addition, in these cell lines, SARS-CoV-MA15 induced the expression of proinflammatory cytokines and IFN-β, mimicking what has been observed in experimental animal models infected with SARS-CoV and SARS patients. These cell lines are valuable tools to perform in vitro studies in a mouse cell system that reflects the species used for in vivo studies of SARS-CoV-MA15 pathogenesis. Copyright © 2013 Elsevier B.V. All rights reserved.
SAR-based change detection using hypothesis testing and Markov random field modelling
NASA Astrophysics Data System (ADS)
Cao, W.; Martinis, S.
2015-04-01
The objective of this study is to automatically detect changed areas caused by natural disasters from bi-temporal co-registered and calibrated TerraSAR-X data. The technique in this paper consists of two steps: Firstly, an automatic coarse detection step is applied based on a statistical hypothesis test for initializing the classification. The original analytical formula as proposed in the constant false alarm rate (CFAR) edge detector is reviewed and rewritten in a compact form of the incomplete beta function, which is a builtin routine in commercial scientific software such as MATLAB and IDL. Secondly, a post-classification step is introduced to optimize the noisy classification result in the previous step. Generally, an optimization problem can be formulated as a Markov random field (MRF) on which the quality of a classification is measured by an energy function. The optimal classification based on the MRF is related to the lowest energy value. Previous studies provide methods for the optimization problem using MRFs, such as the iterated conditional modes (ICM) algorithm. Recently, a novel algorithm was presented based on graph-cut theory. This method transforms a MRF to an equivalent graph and solves the optimization problem by a max-flow/min-cut algorithm on the graph. In this study this graph-cut algorithm is applied iteratively to improve the coarse classification. At each iteration the parameters of the energy function for the current classification are set by the logarithmic probability density function (PDF). The relevant parameters are estimated by the method of logarithmic cumulants (MoLC). Experiments are performed using two flood events in Germany and Australia in 2011 and a forest fire on La Palma in 2009 using pre- and post-event TerraSAR-X data. The results show convincing coarse classifications and considerable improvement by the graph-cut post-classification step.
Antibody-dependent SARS coronavirus infection is mediated by antibodies against spike proteins.
Wang, Sheng-Fan; Tseng, Sung-Pin; Yen, Chia-Hung; Yang, Jyh-Yuan; Tsao, Ching-Han; Shen, Chun-Wei; Chen, Kuan-Hsuan; Liu, Fu-Tong; Liu, Wu-Tse; Chen, Yi-Ming Arthur; Huang, Jason C
2014-08-22
The severe acute respiratory syndrome coronavirus (SARS-CoV) still carries the potential for reemergence, therefore efforts are being made to create a vaccine as a prophylactic strategy for control and prevention. Antibody-dependent enhancement (ADE) is a mechanism through which dengue viruses, feline coronaviruses, and HIV viruses take advantage of anti-viral humoral immune responses to infect host target cells. Here we describe our observations of SARS-CoV using ADE to enhance the infectivity of a HL-CZ human promonocyte cell line. Quantitative-PCR and immunofluorescence staining results indicate that SARS-CoV is capable of replication in HL-CZ cells, and of displaying virus-induced cytopathic effects and increased levels of TNF-α, IL-4 and IL-6 two days post-infection. According to flow cytometry data, the HL-CZ cells also expressed angiotensin converting enzyme 2 (ACE2, a SARS-CoV receptor) and higher levels of the FcγRII receptor. We found that higher concentrations of anti-sera against SARS-CoV neutralized SARS-CoV infection, while highly diluted anti-sera significantly increased SARS-CoV infection and induced higher levels of apoptosis. Results from infectivity assays indicate that SARS-CoV ADE is primarily mediated by diluted antibodies against envelope spike proteins rather than nucleocapsid proteins. We also generated monoclonal antibodies against SARS-CoV spike proteins and observed that most of them promoted SARS-CoV infection. Combined, our results suggest that antibodies against SARS-CoV spike proteins may trigger ADE effects. The data raise new questions regarding a potential SARS-CoV vaccine, while shedding light on mechanisms involved in SARS pathogenesis. Copyright © 2014 Elsevier Inc. All rights reserved.
Functional Flow and Event-Driven Methods for Predicting System Performance
2015-09-01
The thesis process was difficult and at times painful , but the modeling applications were something that I thoroughly enjoyed working through and...21. 2. SAR Mission initiates; SAR Assets conduct search but no objects of interest are found; SAR assets continue to scan but OSC aborts mission...be related to the SAR, so the OSC aborts mission and all Assets RTB. 45 4. SAR Mission initiates; SAR Assets conduct search and find an object of
2004-03-03
JPL Researcher Bruce Chapman at an AirSAR station aboard NASA's DC-8 flying laboratory during the AirSAR 2004 campaign. AirSAR 2004 is a three-week expedition by an international team of scientists that will use an all-weather imaging tool, called the Airborne Synthetic Aperture Radar (AirSAR), in a mission ranging from the tropical rain forests of Central America to frigid Antarctica.
Yeo, Desmond TB; Wang, Zhangwei; Loew, Wolfgang; Vogel, Mika W; Hancu, Ileana
2011-01-01
Purpose To use EM simulations to study the effects of body type, landmark position, and RF body coil type on peak local SAR in 3T MRI. Materials and Methods Numerically computed peak local SAR for four human body models (HBMs) in three landmark positions (head, heart, pelvic) were compared for a high-pass birdcage and a transverse electromagnetic 3T body coil. Local SAR values were normalized to the IEC whole-body average SAR limit of 2.0 W/kg for normal scan mode. Results Local SAR distributions were highly variable. Consistent with previous reports, the peak local SAR values generally occurred in the neck-shoulder area, near rungs, or between tissues of greatly differing electrical properties. The HBM type significantly influenced the peak local SAR, with stockier HBMs, extending extremities towards rungs, displaying the highest SAR. There was also a trend for higher peak SAR in the head-centric and heart-centric positions. The impact of the coil-types studied was not statistically significant. Conclusion The large variability in peak local SAR indicates the need to include more than one HBM or landmark position when evaluating safety of body coils. It is recommended that a HBM with arms near the rungs be included, to create physically realizable high-SAR scenarios. PMID:21509880
Computerized ionospheric tomography based on geosynchronous SAR
NASA Astrophysics Data System (ADS)
Hu, Cheng; Tian, Ye; Dong, Xichao; Wang, Rui; Long, Teng
2017-02-01
Computerized ionospheric tomography (CIT) based on spaceborne synthetic aperture radar (SAR) is an emerging technique to construct the three-dimensional (3-D) image of ionosphere. The current studies are all based on the Low Earth Orbit synthetic aperture radar (LEO SAR) which is limited by long repeat period and small coverage. In this paper, a novel ionospheric 3-D CIT technique based on geosynchronous SAR (GEO SAR) is put forward. First, several influences of complex atmospheric environment on GEO SAR focusing are detailedly analyzed, including background ionosphere and multiple scattering effects (induced by turbulent ionosphere), tropospheric effects, and random noises. Then the corresponding GEO SAR signal model is constructed with consideration of the temporal-variant background ionosphere within the GEO SAR long integration time (typically 100 s to 1000 s level). Concurrently, an accurate total electron content (TEC) retrieval method based on GEO SAR data is put forward through subband division in range and subaperture division in azimuth, obtaining variant TEC value with respect to the azimuth time. The processing steps of GEO SAR CIT are given and discussed. Owing to the short repeat period and large coverage area, GEO SAR CIT has potentials of covering the specific space continuously and completely and resultantly has excellent real-time performance. Finally, the TEC retrieval and GEO SAR CIT construction are performed by employing a numerical study based on the meteorological data. The feasibility and correctness of the proposed methods are verified.
Terrain Measurement with SAR/InSAR
NASA Astrophysics Data System (ADS)
Li, Deren; Liao, Mingsheng; Balz, Timo; Zhang, Lu; Yang, Tianliang
2016-08-01
Terrain measurement and surface motion estimation are the most important applications for commercial and scientific SAR missions. In Dragon-3, we worked on these applications, especially regarding DEM generation, surface motion estimation with SAR time- series for urban subsidence monitoring and landslide motion estimation, as well as developing tomographic SAR processing methods in urban areas.
Excretion and detection of SARS coronavirus and its nucleic acid from digestive system
Wang, Xin-Wei; Li, Jin-Song; Guo, Ting-Kai; Zhen, Bei; Kong, Qing-Xin; Yi, Bin; Li, Zhong; Song, Nong; Jin, Min; Wu, Xiao-Ming; Xiao, Wen-Jun; Zhu, Xiu-Mei; Gu, Chang-Qing; Yin, Jing; Wei, Wei; Yao, Wei; Liu, Chao; Li, Jian-Feng; Ou, Guo-Rong; Wang, Min-Nian; Fang, Tong-Yu; Wang, Gui-Jie; Qiu, Yao-Hui; Wu, Huai-Huan; Chao, Fu-Huan; Li, Jun-Wen
2005-01-01
AIM: To study whether severe acute respiratory syndrome coronavirus (SARS-CoV) could be excreted from digestive system. METHODS: Cell culture and semi-nested RT-PCR were used to detect SARS-CoV and its RNA from 21 stool and urine samples, and a kind of electropositive filter media particles was used to concentrate the virus in 10 sewage samples from two hospitals receiving SARS patients in Beijing in China. RESULTS: It was demonstrated that there was no live SARS-CoV in all samples collected, but the RNA of SARS-CoV could be detected in seven stool samples from SARS patients with any one of the symptoms of fever, malaise, cough, or dyspnea, in 10 sewage samples before disinfection and 3 samples after disinfection from the two hospitals. The RNA could not be detected in urine and stool samples from patients recovered from SARS. CONCLUSION: Nucleic acid of SARS-CoV can be excreted through the stool of patients into sewage system, and the possibility of SARS-CoV transmitting through digestive system cannot be excluded. PMID:16038039
Improvement of the Accuracy of InSAR Image Co-Registration Based On Tie Points - A Review.
Zou, Weibao; Li, Yan; Li, Zhilin; Ding, Xiaoli
2009-01-01
Interferometric Synthetic Aperture Radar (InSAR) is a new measurement technology, making use of the phase information contained in the Synthetic Aperture Radar (SAR) images. InSAR has been recognized as a potential tool for the generation of digital elevation models (DEMs) and the measurement of ground surface deformations. However, many critical factors affect the quality of InSAR data and limit its applications. One of the factors is InSAR data processing, which consists of image co-registration, interferogram generation, phase unwrapping and geocoding. The co-registration of InSAR images is the first step and dramatically influences the accuracy of InSAR products. In this paper, the principle and processing procedures of InSAR techniques are reviewed. One of important factors, tie points, to be considered in the improvement of the accuracy of InSAR image co-registration are emphatically reviewed, such as interval of tie points, extraction of feature points, window size for tie point matching and the measurement for the quality of an interferogram.
Improvement of the Accuracy of InSAR Image Co-Registration Based On Tie Points – A Review
Zou, Weibao; Li, Yan; Li, Zhilin; Ding, Xiaoli
2009-01-01
Interferometric Synthetic Aperture Radar (InSAR) is a new measurement technology, making use of the phase information contained in the Synthetic Aperture Radar (SAR) images. InSAR has been recognized as a potential tool for the generation of digital elevation models (DEMs) and the measurement of ground surface deformations. However, many critical factors affect the quality of InSAR data and limit its applications. One of the factors is InSAR data processing, which consists of image co-registration, interferogram generation, phase unwrapping and geocoding. The co-registration of InSAR images is the first step and dramatically influences the accuracy of InSAR products. In this paper, the principle and processing procedures of InSAR techniques are reviewed. One of important factors, tie points, to be considered in the improvement of the accuracy of InSAR image co-registration are emphatically reviewed, such as interval of tie points, extraction of feature points, window size for tie point matching and the measurement for the quality of an interferogram. PMID:22399966
He, Biao; Zhang, Yuzhen; Xu, Lin; Yang, Weihong; Yang, Fanli; Feng, Yun; Xia, Lele; Zhou, Jihua; Zhen, Weibin; Feng, Ye; Guo, Huancheng
2014-01-01
ABSTRACT Although many severe acute respiratory syndrome-like coronaviruses (SARS-like CoVs) have been identified in bats in China, Europe, and Africa, most have a genetic organization significantly distinct from human/civet SARS CoVs in the receptor-binding domain (RBD), which mediates receptor binding and determines the host spectrum, resulting in their failure to cause human infections and making them unlikely progenitors of human/civet SARS CoVs. Here, a viral metagenomic analysis of 268 bat rectal swabs collected from four counties in Yunnan Province has identified hundreds of sequences relating to alpha- and betacoronaviruses. Phylogenetic analysis based on a conserved region of the RNA-dependent RNA polymerase gene revealed that alphacoronaviruses had diversities with some obvious differences from those reported previously. Full genomic analysis of a new SARS-like CoV from Baoshan (LYRa11) showed that it was 29,805 nucleotides (nt) in length with 13 open reading frames (ORFs), sharing 91% nucleotide identity with human/civet SARS CoVs and the most recently reported SARS-like CoV Rs3367, while sharing 89% with other bat SARS-like CoVs. Notably, it showed the highest sequence identity with the S gene of SARS CoVs and Rs3367, especially in the RBD region. Antigenic analysis showed that the S1 domain of LYRa11 could be efficiently recognized by SARS-convalescent human serum, indicating that LYRa11 is a novel virus antigenically close to SARS CoV. Recombination analyses indicate that LYRa11 is likely a recombinant descended from parental lineages that had evolved into a number of bat SARS-like CoVs. IMPORTANCE Although many severe acute respiratory syndrome-like coronaviruses (SARS-like CoVs) have been discovered in bats worldwide, there are significant different genic structures, particularly in the S1 domain, which are responsible for host tropism determination, between bat SARS-like CoVs and human SARS CoVs, indicating that most reported bat SARS-like CoVs are not the progenitors of human SARS CoV. We have identified diverse alphacoronaviruses and a close relative (LYRa11) to SARS CoV in bats collected in Yunnan, China. Further analysis showed that alpha- and betacoronaviruses have different circulation and transmission dynamics in bat populations. Notably, full genomic sequencing and antigenic study demonstrated that LYRa11 is phylogenetically and antigenically closely related to SARS CoV. Recombination analyses indicate that LYRa11 is a recombinant from certain bat SARS-like CoVs circulating in Yunnan Province. PMID:24719429
The effect of coating on heat generation properties of Iron oxide nanoparticles
NASA Astrophysics Data System (ADS)
Yuan, Yuan
Magnetic nanoparticles have attracted more and more attention for their potential application as heating agents in cancer hyperthermia. The effectiveness of cancer hyperthermia can be increased by using particles that have a higher heat generation rate, quantified by specific absorption rate (SAR), at a smaller applied field. In order to optimize the functionality of nanoparticles as heating agents, it is essential to have a comprehensive understanding of factors that may influence SAR including coating and aggregation. In all biomedical applications, the magnetic particles are coated with surfactants and polymers to enhance biocompatibility, prevent agglomeration and add functionality. Coatings may profoundly influence particles' clustering behavior and magnetic properties. Yet its effect on the heat generation rate of the nanoparticles has been scarcely investigated. In this context, a systematic investigation was carried out in this dissertation in order to understand the impact of the surface coating of magnetic nanoparticles on their heat generation rate. The study also includes investigation of normal nerve cell viability in presence of biofunctionalized magnetic nanoparticles with and without exposure to magnetic heating. Commercially available suspensions of iron oxide nanoparticles with a diameter of approximately 10 nm and different coatings relevant to biomedical applications such as aminosilane, carboxymethyl-dextran, protein A, biotin were extensively characterized. First of all, magnetic phase reduction of magnetite nanoparticles was examined by studying the discrepancy between the volume fraction of magnetic phase calculated from magnetization curve and the magnetic core concentration obtained from Tiron chelation test. The findings indicated that coatings might interact with the surface atoms of the magnetic core and form a magnetically disordered layer reducing the total amount of the magnetic phase. Secondly, the impact of coating and aggregation on magnetic properties and heat generation rate of magnetic nanoparticles was investigated by comparing the experimental and predicted SAR. For this purpose, AC magnetic susceptibility of suspensions was measured and also calculated by Debye model. Both were used to predict SAR and then compare it to the measured SAR. Poor agreement was found when the predictions were based on the Debye model, which neglects dipolar interactions between nanoparticles within aggregations. For uncoated and amine-functionalized particles (with aggregations) experimental SAR was found to agree relatively well with predicted SAR using experimental susceptibility values, which is expected to capture magnetic losses. For biotin and protein A coated nanoparticles (both having large, asymmetric clusters), the experimental SAR of both samples was found to be higher than the SAR predicted with experimental susceptibility. This unexpected discrepancy was attributed in part to friction loss associated with the partial rotation of clusters. This hypothesis was confirmed by examining the temperature increasing rate of particles embeded in hydrogel with different stiffness. At last, the properties of magnetic nanoparticles dispersed in DI water, Neurobasal (NB), or astrocyte culture media were studied. The aminosilane coated nanoparticles that dispersed in astrocyte culture media presented highest susceptibility and SAR compared to that suspended in DI water or NB, which was attributed to its highest aggregation size and magnetization phase concentration. However, for starch coated nanoparticles, samples prepared in either media showed similar magnetic and heating properties. The cell studies started with investigation of the response of primary cortical neurons to magnetite nanoparticles with aminosilane, starch and polydimethylamine coatings. It was found that polydimethylamine functionalized nanoparticles induce cell death at all concentrations and complete removal of plasma membrane. Aminosilane and starch-coated particles affected metabolic activities only at higher concentrations while leaving the membrane intact. The iron oxide nanoparticle with aminosilane coating were then used to further study the response of neurons and astrocytes to local heat generated by magnetic nanoparticles. The culture results show that heating does not affect viability of neurons but influence the viability of astrocytes independent of final temperature.
Severe acute respiratory syndrome (SARS)
SARS; Respiratory failure - SARS ... Complications may include: Respiratory failure Liver failure Heart failure ... 366. McIntosh K, Perlman S. Coronaviruses, including severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). ...
Satellite SAR geocoding with refined RPC model
NASA Astrophysics Data System (ADS)
Zhang, Lu; Balz, Timo; Liao, Mingsheng
2012-04-01
Recent studies have proved that the Rational Polynomial Camera (RPC) model is able to act as a reliable replacement of the rigorous Range-Doppler (RD) model for the geometric processing of satellite SAR datasets. But its capability in absolute geolocation of SAR images has not been evaluated quantitatively. Therefore, in this article the problems of error analysis and refinement of SAR RPC model are primarily investigated to improve the absolute accuracy of SAR geolocation. Range propagation delay and azimuth timing error are identified as two major error sources for SAR geolocation. An approach based on SAR image simulation and real-to-simulated image matching is developed to estimate and correct these two errors. Afterwards a refined RPC model can be built from the error-corrected RD model and then used in satellite SAR geocoding. Three experiments with different settings are designed and conducted to comprehensively evaluate the accuracies of SAR geolocation with both ordinary and refined RPC models. All the experimental results demonstrate that with RPC model refinement the absolute location accuracies of geocoded SAR images can be improved significantly, particularly in Easting direction. In another experiment the computation efficiencies of SAR geocoding with both RD and RPC models are compared quantitatively. The results show that by using the RPC model such efficiency can be remarkably improved by at least 16 times. In addition the problem of DEM data selection for SAR image simulation in RPC model refinement is studied by a comparative experiment. The results reveal that the best choice should be using the proper DEM datasets of spatial resolution comparable to that of the SAR images.
Local SAR in parallel transmission pulse design.
Lee, Joonsung; Gebhardt, Matthias; Wald, Lawrence L; Adalsteinsson, Elfar
2012-06-01
The management of local and global power deposition in human subjects (specific absorption rate, SAR) is a fundamental constraint to the application of parallel transmission (pTx) systems. Even though the pTx and single channel have to meet the same SAR requirements, the complex behavior of the spatial distribution of local SAR for transmission arrays poses problems that are not encountered in conventional single-channel systems and places additional requirements on pTx radio frequency pulse design. We propose a pTx pulse design method which builds on recent work to capture the spatial distribution of local SAR in numerical tissue models in a compressed parameterization in order to incorporate local SAR constraints within computation times that accommodate pTx pulse design during an in vivo magnetic resonance imaging scan. Additionally, the algorithm yields a protocol-specific ultimate peak in local SAR, which is shown to bound the achievable peak local SAR for a given excitation profile fidelity. The performance of the approach was demonstrated using a numerical human head model and a 7 Tesla eight-channel transmit array. The method reduced peak local 10 g SAR by 14-66% for slice-selective pTx excitations and 2D selective pTx excitations compared to a pTx pulse design constrained only by global SAR. The primary tradeoff incurred for reducing peak local SAR was an increase in global SAR, up to 34% for the evaluated examples, which is favorable in cases where local SAR constraints dominate the pulse applications. Copyright © 2011 Wiley Periodicals, Inc.
Autofocus algorithm for curvilinear SAR imaging
NASA Astrophysics Data System (ADS)
Bleszynski, E.; Bleszynski, M.; Jaroszewicz, T.
2012-05-01
We describe an approach to autofocusing for large apertures on curved SAR trajectories. It is a phase-gradient type method in which phase corrections compensating trajectory perturbations are estimated not directly from the image itself, but rather on the basis of partial" SAR data { functions of the slow and fast times { recon- structed (by an appropriate forward-projection procedure) from windowed scene patches, of sizes comparable to distances between distinct targets or localized features of the scene. The resulting partial data" can be shown to contain the same information on the phase perturbations as that in the original data, provided the frequencies of the perturbations do not exceed a quantity proportional to the patch size. The algorithm uses as input a sequence of conventional scene images based on moderate-size subapertures constituting the full aperture for which the phase corrections are to be determined. The subaperture images are formed with pixel sizes comparable to the range resolution which, for the optimal subaperture size, should be also approximately equal the cross-range resolution. The method does not restrict the size or shape of the synthetic aperture and can be incorporated in the data collection process in persistent sensing scenarios. The algorithm has been tested on the publicly available set of GOTCHA data, intentionally corrupted by random-walk-type trajectory uctuations (a possible model of errors caused by imprecise inertial navigation system readings) of maximum frequencies compatible with the selected patch size. It was able to eciently remove image corruption for apertures of sizes up to 360 degrees.
Effects of field orientation during 700-MHz radiofrequency irradiation of rats
DOE Office of Scientific and Technical Information (OSTI.GOV)
Frei, M.R.; Jauchem, J.R.; Padilla, J.M.
1989-01-01
Ketamine-anesthetized Sprague-Dawley rats were exposed to far-field 700-MHz continuous-wave radiofrequency radiation (RFR) in both E and H orientations. Irradiation was conducted at whole-body average specific absorption rates (SARs) of 9.2 and 13.0 W/kg (E and H, respectively) that resulted in approximately equivalent colonic specific heating rates (SHRs). Exposures were performed to repeatedly increase colonic temperature by 1 deg C (38.5 to 39.5 deg C). Tympanic, tail, left and right subcutaneous (toward and away from RFR source), and colonic temperatures, arterial blood pressure, and respiratory rate were continuously recorded. In spite of equivalent colonic SHRs and the reduced E-orientation average SAR,more » the right subcutaneous, tympanic, and tail SARs, SHRs and absolute temperature increases were significantly greater in E than in H orientation. The cooling rate at all monitoring sites was also significantly greater in E than in H orientation. Heart rate and mean arterial blood pressure significantly increased during irradiation; however, changer between orientations were not different. Respiratory rate significantly increased during irradiation in H, but not in E orientation. These results indicate that during resonant frequency irradiation, differences occur in the pattern of heat deposition between E- and H-orientation exposure. When compared with previous investigations performed at supraresonant frequencies, the lower level of cardiovascular change in this study was probably related to the lower periphery-to-core thermal gradient.« less
Effects of field orientation during 700-MHz radiofrequency irradiation of rats
DOE Office of Scientific and Technical Information (OSTI.GOV)
Frei, M.R.; Jauchem, J.R.; Padilla, J.M.
1989-01-01
Ketamine-anesthetized Sprague-Dawley rats were exposed to far-field 700-MHz continuous-wave radiofrequency radiation (RFR) in both E and H orientations. Irradiation was conducted at whole-body average specific absorption rates (SARs) of 9.2 and 13.0 W/kg (E and H, respectively) that resulted in approximately equivalent colonic specific heating rates (SHRs). Exposures were performed to repeatedly increase colonic temperature by 1 degree C (38.5 to 39.5 degrees C). Tympanic, tail, left and right subcutaneous (toward and away from RFR source), and colonic temperatures, arterial blood pressure, and respiratory rate were continuously recorded. In spite of equivalent colonic SHRs and the reduced E-orientation average SAR,more » the right subcutaneous, tympanic, and tail SARs, SHRs and absolute temperature increases were significantly greater in E than in H orientation. The cooling rate at all monitoring sites was also significantly greater in E than in H orientation. Heart rate and mean arterial blood pressure significantly increased during irradiation; however, changes between orientations were not different. Respiratory rate significantly increased during irradiation in H, but not in E orientation. These results indicate that during resonant frequency irradiation, differences occur in the pattern of heat deposition between E- and H-orientation exposure. When compared with previous investigations performed at supraresonant frequencies, the lower level of cardiovascular change in this study was probably related to the lower periphery-to-core thermal gradient.« less
2004-03-03
JPL Researcher Tim Miller at the primary AirSAR station aboard NASA's DC-8 flying laboratory during the AirSAR 2004 campaign. AirSAR 2004 is a three-week expedition by an international team of scientists that will use an all-weather imaging tool, called the Airborne Synthetic Aperture Radar (AirSAR), in a mission ranging from the tropical rain forests of Central America to frigid Antarctica.
Radar transponder apparatus and signal processing technique
Axline, Jr., Robert M.; Sloan, George R.; Spalding, Richard E.
1996-01-01
An active, phase-coded, time-grating transponder and a synthetic-aperture radar (SAR) and signal processor means, in combination, allow the recognition and location of the transponder (tag) in the SAR image and allow communication of information messages from the transponder to the SAR. The SAR is an illuminating radar having special processing modifications in an image-formation processor to receive an echo from a remote transponder, after the transponder receives and retransmits the SAR illuminations, and to enhance the transponder's echo relative to surrounding ground clutter by recognizing special transponder modulations from phase-shifted from the transponder retransmissions. The remote radio-frequency tag also transmits information to the SAR through a single antenna that also serves to receive the SAR illuminations. Unique tag-modulation and SAR signal processing techniques, in combination, allow the detection and precise geographical location of the tag through the reduction of interfering signals from ground clutter, and allow communication of environmental and status information from said tag to be communicated to said SAR.
Radar transponder apparatus and signal processing technique
Axline, R.M. Jr.; Sloan, G.R.; Spalding, R.E.
1996-01-23
An active, phase-coded, time-grating transponder and a synthetic-aperture radar (SAR) and signal processor means, in combination, allow the recognition and location of the transponder (tag) in the SAR image and allow communication of information messages from the transponder to the SAR. The SAR is an illuminating radar having special processing modifications in an image-formation processor to receive an echo from a remote transponder, after the transponder receives and retransmits the SAR illuminations, and to enhance the transponder`s echo relative to surrounding ground clutter by recognizing special transponder modulations from phase-shifted from the transponder retransmissions. The remote radio-frequency tag also transmits information to the SAR through a single antenna that also serves to receive the SAR illuminations. Unique tag-modulation and SAR signal processing techniques, in combination, allow the detection and precise geographical location of the tag through the reduction of interfering signals from ground clutter, and allow communication of environmental and status information from said tag to be communicated to said SAR. 4 figs.
Development of chemical inhibitors of the SARS coronavirus: viral helicase as a potential target.
Keum, Young-Sam; Jeong, Yong-Joo
2012-11-15
Severe acute respiratory syndrome (SARS) was the first pandemic in the 21st century to claim more than 700 lives worldwide. However, effective anti-SARS vaccines or medications are currently unavailable despite being desperately needed to adequately prepare for a possible SARS outbreak. SARS is caused by a novel coronavirus, and one of its components, a viral helicase, is emerging as a promising target for the development of chemical SARS inhibitors. In the following review, we describe the characterization, family classification, and kinetic movement mechanisms of the SARS coronavirus (SCV) helicase-nsP13. We also discuss the recent progress in the identification of novel chemical inhibitors of nsP13 in the context of our recent discovery of the strong inhibition of the SARS helicase by natural flavonoids, myricetin and scutellarein. These compounds will serve as important resources for the future development of anti-SARS medications. Copyright © 2012 Elsevier Inc. All rights reserved.
Cross-calibration between airborne SAR sensors
NASA Technical Reports Server (NTRS)
Zink, Manfred; Olivier, Philippe; Freeman, Anthony
1993-01-01
As Synthetic Aperture Radar (SAR) system performance and experience in SAR signature evaluation increase, quantitative analysis becomes more and more important. Such analyses require an absolute radiometric calibration of the complete SAR system. To keep the expenditure on calibration of future multichannel and multisensor remote sensing systems (e.g., X-SAR/SIR-C) within a tolerable level, data from different tracks and different sensors (channels) must be cross calibrated. The 1989 joint E-SAR/DC-8 SAR calibration campaign gave a first opportunity for such an experiment, including cross sensor and cross track calibration. A basic requirement for successful cross calibration is the stability of the SAR systems. The calibration parameters derived from different tracks and the polarimetric properties of the uncalibrated data are used to describe this stability. Quality criteria for a successful cross calibration are the agreement of alpha degree values and the consistency of radar cross sections of equally sized corner reflectors. Channel imbalance and cross talk provide additional quality in case of the polarimetric DC-8 SAR.
NASA Astrophysics Data System (ADS)
Oliver-Cabrera, T.; Wdowinski, S.; Kruse, S.
2016-12-01
Central Florida's thick carbonate deposits and hydrological conditions make the area prone to sinkhole development. Sinkhole collapse is a major geologic hazard, threatening human life and causing substantial damage to property. Detecting sinkhole deformation before a collapse is a difficult task, due to small and typically unnoticeable surface changes. Most techniques used to map sinkholes, such as ground penetrating radar, require ground contact and are practical for localized (typically 2D, tens to hundreds of meters) surveys but not for broad study areas. In this study we use Persistent Scatterer (PS) time series analysis of Interferometric Synthetic Aperture Radar (InSAR), which is a very useful technique for detecting localized deformation while covering vast areas. We acquired SAR images over four locations in central Florida in order to detect possible pre-collapse or slow subsidence surface movements. The data used in this study were acquired by TerraSAR-X and COSMO-SkyMed satellites with pixel resolutions ranging between 25cm and 2m. To date, we have obtained four datasets, each of 25-30 acquisitions, covering a period of roughly one year over a total of roughly 2200 km2. We also installed two corner reflectors over a subsiding sinkhole located in an open vegetated area, to provide strong scattering and improve coherence over that particular location. We generate PS time series for each of the four datasets. Preliminary results show localized deformation at several houses and commercial buildings in several locations. Deforming areas vary in size from approximately 10mx20m of a single house to 60mx60m for a commercial building. On site ground penetrating radar surveys will be performed in these areas to verify their relationship to possible sinkhole activities. Our results also confirm that the corner reflectors improved PS detection over low coherence areas.
Context-sensitive design and human interaction principles for usable, useful, and adoptable radars
NASA Astrophysics Data System (ADS)
McNamara, Laura A.; Klein, Laura M.
2016-05-01
The evolution of exquisitely sensitive Synthetic Aperture Radar (SAR) systems is positioning this technology for use in time-critical environments, such as search-and-rescue missions and improvised explosive device (IED) detection. SAR systems should be playing a keystone role in the United States' Intelligence, Surveillance, and Reconnaissance activities. Yet many in the SAR community see missed opportunities for incorporating SAR into existing remote sensing data collection and analysis challenges. Drawing on several years' of field research with SAR engineering and operational teams, this paper examines the human and organizational factors that mitigate against the adoption and use of SAR for tactical ISR and operational support. We suggest that SAR has a design problem, and that context-sensitive, human and organizational design frameworks are required if the community is to realize SAR's tactical potential.
Further SEASAT SAR coastal ocean wave analysis
NASA Technical Reports Server (NTRS)
Kasischke, E. S.; Shuchman, R. A.; Meadows, G. A.; Jackson, P. L.; Tseng, Y.
1981-01-01
Analysis techniques used to exploit SEASAT synthetic aperture radar (SAR) data of gravity waves are discussed and the SEASAT SAR's ability to monitor large scale variations in gravity wave fields in both deep and shallow water is evaluated. The SAR analysis techniques investigated included motion compensation adjustments and the semicausal model for spectral analysis of SAR wave data. It was determined that spectra generated from fast Fourier transform analysis (FFT) of SAR wave data were not significantly altered when either range telerotation adjustments or azimuth focus shifts were used during processing of the SAR signal histories, indicating that SEASAT imagery of gravity waves is not significantly improved or degraded by motion compensation adjustments. Evaluation of the semicausal (SC) model using SEASAT SAR data from Rev. 974 indicates that the SC spectral estimates were not significantly better than the FFT results.
Lack of SARS transmission and U.S. SARS case-patient.
Peck, Angela J; Newbern, E Claire; Feikin, Daniel R; Issakbaeva, Elmira T; Park, Benjamin J; Fehr, Jason; LaMonte, Ashley C; Le, Thong P; Burger, Terry L; Rhodes, Luther V; Weltman, Andre; Erdman, Dean; Ksiazek, Thomas G; Lingappa, Jairam R
2004-02-01
In early April 2003, severe acute respiratory syndrome (SARS) was diagnosed in a Pennsylvania resident after his exposure to persons with SARS in Toronto, Canada. To identify contacts of the case-patient and evaluate the risk for SARS transmission, a detailed epidemiologic investigation was performed. On the basis of this investigation, 26 persons (17 healthcare workers, 4 household contacts, and 5 others) were identified as having had close contact with this case-patient before infection-control practices were implemented. Laboratory evaluation of clinical specimens showed no evidence of transmission of SARS-associated coronavirus (SARS-CoV) infection to any close contact of this patient. This investigation documents that, under certain circumstances, SARS-CoV is not readily transmitted to close contacts, despite ample unprotected exposures. Improving the understanding of risk factors for transmission will help focus public health control measures.
The Membrane Dynamics of Pexophagy Are Influenced by Sar1p in Pichia pastoris
Schroder, Laura A.; Ortiz, Michael V.
2008-01-01
Several Sec proteins including a guanosine diphosphate/guanosine triphosphate exchange factor for Sar1p have been implicated in autophagy. In this study, we investigated the role of Sar1p in pexophagy by expressing dominant-negative mutant forms of Sar1p in Pichia pastoris. When expressing sar1pT34N or sar1pH79G, starvation-induced autophagy, glucose-induced micropexophagy, and ethanol-induced macropexophagy are dramatically suppressed. These Sar1p mutants did not affect the initiation or expansion of the sequestering membranes nor the trafficking of Atg11p and Atg9p to these membranes during micropexophagy. However, the lipidation of Atg8p and assembly of the micropexophagic membrane apparatus, which are essential to complete the incorporation of the peroxisomes into the degradative vacuole, were inhibited when either Sar1p mutant protein was expressed. During macropexophagy, the expression of sar1pT34N inhibited the formation of the pexophagosome, whereas sar1pH79G suppressed the delivery of the peroxisome from the pexophagosome to the vacuole. The pexophagosome contained Atg8p in wild-type cells, but in cells expressing sar1pH79G these organelles contain both Atg8p and endoplasmic reticulum components as visualized by DsRFP-HDEL. Our results demonstrate key roles for Sar1p in both micro- and macropexophagy. PMID:18768759
Surface vimentin is critical for the cell entry of SARS-CoV.
Yu, Yvonne Ting-Chun; Chien, Ssu-Chia; Chen, I-Yin; Lai, Chia-Tsen; Tsay, Yeou-Guang; Chang, Shin C; Chang, Ming-Fu
2016-01-22
Severe acute respiratory syndrome coronavirus (SARS-CoV) caused a global panic due to its high morbidity and mortality during 2002 and 2003. Soon after the deadly disease outbreak, the angiotensin-converting enzyme 2 (ACE2) was identified as a functional cellular receptor in vitro and in vivo for SARS-CoV spike protein. However, ACE2 solely is not sufficient to allow host cells to become susceptible to SARS-CoV infection, and other host factors may be involved in SARS-CoV spike protein-ACE2 complex. A host intracellular filamentous cytoskeletal protein vimentin was identified by immunoprecipitation and LC-MS/MS analysis following chemical cross-linking on Vero E6 cells that were pre-incubated with the SARS-CoV spike protein. Moreover, flow cytometry data demonstrated an increase of the cell surface vimentin level by 16.5 % after SARS-CoV permissive Vero E6 cells were treated with SARS-CoV virus-like particles (VLPs). A direct interaction between SARS-CoV spike protein and host surface vimentin was further confirmed by far-Western blotting. In addition, antibody neutralization assay and shRNA knockdown experiments indicated a vital role of vimentin in cell binding and uptake of SARS-CoV VLPs and the viral spike protein. A direct interaction between vimentin and SARS-CoV spike protein during viral entry was observed. Vimentin is a putative anti-viral drug target for preventing/reducing the susceptibility to SARS-CoV infection.
Space Radar Image of Colombian Volcano
NASA Technical Reports Server (NTRS)
1999-01-01
This is a radar image of a little known volcano in northern Colombia. The image was acquired on orbit 80 of space shuttle Endeavour on April 14, 1994, by the Spaceborne Imaging Radar C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR). The volcano near the center of the image is located at 5.6 degrees north latitude, 75.0 degrees west longitude, about 100 kilometers (65 miles) southeast of Medellin, Colombia. The conspicuous dark spot is a lake at the bottom of an approximately 3-kilometer-wide (1.9-mile) volcanic collapse depression or caldera. A cone-shaped peak on the bottom left (northeast rim) of the caldera appears to have been the source for a flow of material into the caldera. This is the northern-most known volcano in South America and because of its youthful appearance, should be considered dormant rather than extinct. The volcano's existence confirms a fracture zone proposed in 1985 as the northern boundary of volcanism in the Andes. The SIR-C/X-SAR image reveals another, older caldera further south in Colombia, along another proposed fracture zone. Although relatively conspicuous, these volcanoes have escaped widespread recognition because of frequent cloud cover that hinders remote sensing imaging in visible wavelengths. Four separate volcanoes in the Northern Andes nations ofColombia and Ecuador have been active during the last 10 years, killing more than 25,000 people, including scientists who were monitoring the volcanic activity. Detection and monitoring of volcanoes from space provides a safe way to investigate volcanism. The recognition of previously unknown volcanoes is important for hazard evaluations because a number of major eruptions this century have occurred at mountains that were not previously recognized as volcanoes. Spaceborne Imaging Radar-C and X-band Synthetic Aperture Radar (SIR-C/X-SAR) is part of NASA's Mission to Planet Earth. The radars illuminate Earth with microwaves allowing detailed observations at any time, regardless of weather or sunlight conditions. SIR-C/X-SAR uses three microwave wavelengths: L-band (24 cm), C-band (6 cm) and X-band (3 cm). The multi-frequency data will be used by the international scientific community to better understand the global environment and how it is changing. The SIR-C/X-SAR data, complemented by aircraft and ground studies, will give scientists clearer insights into those environmental changes which are caused by nature and those changes which are induced by human activity. SIR-C was developed by NASA's Jet Propulsion Laboratory. X-SAR was developed by the Dornier and Alenia Spazio companiesfor the German space agency, Deutsche Agentur fuer Raumfahrtange-legenheiten (DARA), and the Italian space agency,Agenzia SpazialeItaliana (ASI), with the Deutsche Forschungsanstalt fuer Luft undRaumfahrt e.v.(DLR), the major partner in science,operations, and data processing of X-SAR.
Three frequency false color image of Flevoland, the Netherlands
1994-04-18
STS059-S-086 (18 April 1994) --- This is a three-frequency false-color image of Flevoland, the Netherlands, centered at 52.4 degrees north latitude, and 5.4 degrees east longitude. This image was acquired by the Spaceborne Imaging Radar-C and X-Band Synthetic Aperture Radar (SIR-C/X-SAR) aboard the Space Shuttle Endeavour on April 14, 1994. It was produced by combining data from the X-Band, C-Band and L-Band radar's. The area shown is approximately 25 by 28 kilometers (15 1/2 by 17 1/2 miles). Flevoland, which fills the lower two-thirds of the image, is a very flat area that is made up of reclaimed land that is used for agriculture and forestry. At the top of the image, across the canal from Flevoland, is an older forest shown in red; the city of Harderwijk is shown in white on the shore of the canal. At this time of the year, the agricultural fields are bare soil, and they show up in this images in blue. The changes in the brightness of the blue areas are equal to the changes in roughness. The dark blue areas are water and the small dots in the canal are boats. This SIR-C/X-SAR supersite is being used for both calibration and agricultural studies. Several soil and crop ground-truth studies will be conducted during the Shuttle flight. In addition, about 10 calibration devices and 10 corner reflectors have been deployed to calibrate and monitor the radar signal. One of these transponders can be seen as a bright star in the lower right quadrant of the image. This false-color image was made using L-Band total power in the red channel, C-Band total power in the green channel, and X-Band VV polarization in the blue channel. SIR-C/X-SAR is part of NASA's Mission to Planet Earth (MTPE). SIR-C/X-SAR radars illuminate Earth with microwaves allowing detailed observations at any time, regardless of weather or sunlight conditions. SIR-C/X-SAR uses three microwave wavelengths: L-Band (24 cm), C-Band (6 cm), and X-Band (3 cm). The multi-frequency data will be used by the international scientific community to better understand the global environment and how it is changing. The SIR-C/X-SAR data, complemented by aircraft and ground studies, will give scientists clearer insights into those environmental changes which are caused by nature and those changes which are induced by human activity. SIR-C was developed by NASA's Jet Propulsion Laboratory (JPL). X-SAR was developed by the Dornire and Alenia Spazio Companies for the German Space Agency, Deutsche Agentur fuer Raumfahrtangelegenheiten (DARA), and the Italian Space Agency, Agenzia Spaziale Italiana (ASI). JPL Photo ID: P-43941
False-color composite of Oetztal, Austria
1994-04-13
STS059-S-072 (13 April 1994) --- This image is a false-color composite of Oetztal, Austria located in the Central Alps, centered at 46.8 degrees north latitude, and 10.70 degrees east longitude, at the border between Switzerland (top), Italy (left) and Austria (right and bottom). The area shown is 50 kilometers (30 miles) south of Innsbruck, Austria. This image was acquired by the Spaceborne Imaging Radar-C and X-Band Synthetic Aperture Radar (SIR-C/X-SAR) aboard the Space Shuttle Endeavour on its 14th orbit. Oetztal is a SIR-C/X-SAR hydrology supersite. Approximately one quarter of this image is covered by glaciers, the largest of which, Gepatschferner, is visible as a triangular yellow patch in the center of the scene. The summits of the main peaks reach elevations between 3,500 and 3,768 meters (11,500 and 12,362 feet) above sea level. The tongues of the glaciers are descending from elevated plateaus down into narrow valleys which were formed during the last ice age. This color image was produced in C-Band using multi-polarization information (Red=CHV, Green=CVV, Blue=CVV/CHV). The blue areas are lakes (Gepatsch Dam at center right; Lake Muta at top right) and glacier ice. The yellow areas are slopes facing the radar and areas of dry snow. Purple corresponds to slopes facing away from the radar. Yellow in the valley bottom corresponds to tree covered areas. There is 30 to 50 centimeters (12 to 20 inches) of dry, fresh snow on the glaciers, and about 10 centimeters (4 inches) in the valley at the city of Vent, Austria (center). At these data were taken, the weather was cold, with snow and thick fog. The entire area would appear white to an optical sensor because it is all covered under a winter snowpack. Researchers are interested in Oetztal because knowing how glaciers shrink and grow over time is an important indication of climatic change. SIR-C/X-SAR is part of NASA's Mission to Planet Earth (MTPE). SIR-C/X-SAR radars illuminate Earth with microwaves allowing detailed observations at any time, regardless of weather or sunlight conditions. SIR-C/X-SAR uses three microwave wavelengths: L-Band (24 cm), C-Band (6 cm), and X-Band (3 cm). The multi-frequency data will be used by the international scientific community to better understand the global environment and how it is changing. The SIR-C/X-SAR data, complemented by aircraft and ground studies, will give scientists clearer insights into those environmental changes which are caused by nature and those changes which are induced by human activity. SIR-C was developed by NASA's Jet Propulsion Laboratory (JPL). X-SAR was developed by the Dornire and Alenia Spazio Companies for the German Space Agency, Deutsche Agentur fuer Raumfahrtangelegenheiten (DARA), and the Italian Space Agency, Agenzia Spaziale Italiana (ASI). JPL Photo ID: P-43890
Space Radar Image of Flevoland, Netherlands
NASA Technical Reports Server (NTRS)
1999-01-01
This is a three-frequency false color image of Flevoland, The Netherlands, centered at 52.4 degrees north latitude, 5.4 degrees east longitude. This image was acquired by the Spaceborne Imaging Radar-C and X-Band Synthetic Aperture Radar (SIR-C/X-SAR) aboard space shuttle Endeavour on April 14, 1994. It was produced by combining data from the X-band, C-band and L-band radars. The area shown is approximately 25 kilometers by 28 kilometers (15-1/2 by 17-1/2 miles). Flevoland, which fills the lower two-thirds of the image, is a very flat area that is made up of reclaimed land that is used for agriculture and forestry. At the top of the image, across the canal from Flevoland, is an older forest shown in red; the city of Harderwijk is shown in white on the shore of the canal. At this time of the year, the agricultural fields are bare soil, and they show up in this image in blue. The changes in the brightness of the blue areas are equal to the changes in roughness. The dark blue areas are water and the small dots in the canal are boats. This SIR-C/X-SAR supersite is being used for both calibration and agricultural studies. Several soil and crop ground-truth studies will be conducted during the shuttle flight. In addition, about 10calibration devices and 10 corner reflectors have been deployed to calibrate and monitor the radar signal. One of these transponders can be seen as a bright star in the lower right quadrant of the image. This false-color image was made using L-band total power in the red channel, C-band total power in the green channel, and X-band VV polarization in the blue channel. Spaceborne Imaging Radar-C and X-Synthetic Aperture Radar (SIR-C/X-SAR) is part of NASA's Mission to Planet Earth. The radars illuminate Earth with microwaves allowing detailed observations at any time, regardless of weather or sunlight conditions. SIR-C/X-SAR uses three microwave wavelengths: L-band (24 cm), C-band (6 cm) and X-band (3 cm). The multi-frequency data will be used by the international scientific community to better understand the global environment and how it is changing. The SIR-C/X-SAR data, complemented by aircraft and ground studies, will give scientists clearer insights into those environmental changes which are caused by nature and those changes which are induced by human activity. SIR-C was developed by NASA's Jet Propulsion Laboratory. X-SAR was developed by the Dornier and Alenia Spazio companies for the German space agency, Deutsche Agentur fuer Raumfahrtangelegenheiten (DARA), and the Italian space agency, Agenzia Spaziale Italiana (ASI), with the Deutsche Forschungsanstalt fuer Luft und Raumfahrte.v. (DLR), the major partner in science, operations and data processing of X-SAR.Cai, Hancheng; Li, Zibo; Huang, Chiun-Wei; Park, Ryan; Shahinian, Anthony H; Conti, Peter S
2010-01-01
Stable attachment of (64)Cu(2+) to a targeting molecule usually requires the use of a bifunctional chelator (BFC). Sarcophagine (Sar) ligands rapidly coordinate (64)Cu(2+) within the multiple macrocyclic rings comprising the cage structure under mild conditions, providing high stability in vivo. Previously, we have designed a new versatile cage-like BFC Sar ligand, 4-((8-amino-3,6,10,13,16,19-hexaazabicyclo[6.6.6]icosane-1-ylamino)methyl)benzoic acid (AmBaSar), for (64)Cu radiopharmaceuticals. Here we report the improved synthesis of AmBaSar, (64)Cu(2+) labeling conditions and its biological evaluation compared with the known BFC 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid (DOTA). The AmBaSar was synthesized in four steps starting from (1,8-diamine-Sar) cobalt(III) pentachloride ([Co(DiAmSar)]Cl(5)) using an improved synthetic method. The AmBaSar was labeled with (64)Cu(2+) in pH 5.0 ammonium acetate buffer solution at room temperature, followed by analysis and purification with HPLC. The in vitro stability of (64)Cu-AmBaSar complex was evaluated in phosphate buffered saline (PBS), fetal bovine serum and mouse blood. The microPET imaging and biodistribution studies of (64)Cu-AmBaSar were performed in Balb/c mice, and the results were compared with (64)Cu-DOTA. The AmBaSar was readily prepared and characterized by MS and (1)H NMR. The radiochemical yield of (64)Cu-AmBaSar was >or=98% after 30 min of incubation at 25 degrees C. The (64)Cu-AmBaSar complex was analyzed and purified by HPLC with a retention time of 17.9 min. The radiochemical purity of (64)Cu-AmBaSar was more than 97% after 26 h of incubation in PBS or serum. The biological evaluation of (64)Cu-AmBaSar in normal mouse demonstrated renal clearance as the primary mode of excretion, with improved stability in vivo compared to (64)Cu-DOTA. The new cage-like BFC AmBaSar was prepared using a simplified synthetic method. The (64)Cu-AmBaSar complex could be obtained rapidly with high radiochemical yield (>/=98%) under mild conditions. In vitro and in vivo evaluation of AmBaSar demonstrated its promising potential for preparation of (64)Cu radiopharmaceuticals. Copyright 2010. Published by Elsevier Inc.
Polarimetric SAR image classification based on discriminative dictionary learning model
NASA Astrophysics Data System (ADS)
Sang, Cheng Wei; Sun, Hong
2018-03-01
Polarimetric SAR (PolSAR) image classification is one of the important applications of PolSAR remote sensing. It is a difficult high-dimension nonlinear mapping problem, the sparse representations based on learning overcomplete dictionary have shown great potential to solve such problem. The overcomplete dictionary plays an important role in PolSAR image classification, however for PolSAR image complex scenes, features shared by different classes will weaken the discrimination of learned dictionary, so as to degrade classification performance. In this paper, we propose a novel overcomplete dictionary learning model to enhance the discrimination of dictionary. The learned overcomplete dictionary by the proposed model is more discriminative and very suitable for PolSAR classification.
SAR image registration based on Susan algorithm
NASA Astrophysics Data System (ADS)
Wang, Chun-bo; Fu, Shao-hua; Wei, Zhong-yi
2011-10-01
Synthetic Aperture Radar (SAR) is an active remote sensing system which can be installed on aircraft, satellite and other carriers with the advantages of all day and night and all-weather ability. It is the important problem that how to deal with SAR and extract information reasonably and efficiently. Particularly SAR image geometric correction is the bottleneck to impede the application of SAR. In this paper we introduces image registration and the Susan algorithm knowledge firstly, then introduces the process of SAR image registration based on Susan algorithm and finally presents experimental results of SAR image registration. The Experiment shows that this method is effective and applicable, no matter from calculating the time or from the calculation accuracy.
Processor architecture for airborne SAR systems
NASA Technical Reports Server (NTRS)
Glass, C. M.
1983-01-01
Digital processors for spaceborne imaging radars and application of the technology developed for airborne SAR systems are considered. Transferring algorithms and implementation techniques from airborne to spaceborne SAR processors offers obvious advantages. The following topics are discussed: (1) a quantification of the differences in processing algorithms for airborne and spaceborne SARs; and (2) an overview of three processors for airborne SAR systems.
2004-03-10
School children from Punta Arenas, Chile, talk with Dr. David Imel, an AirSAR scientist from NASA JPL, during AirSAR 2004. AirSAR 2004 is a three-week expedition by an international team of scientists that uses an all-weather imaging tool, called the Airborne Synthetic Aperture Radar (AirSAR) which is located onboard NASA's DC-8 airborne laboratory. Scientists from many parts of the world including NASA's Jet Propulsion Laboratory are combining ground research done in several areas in Central and South America with NASA's AirSAR technology to improve and expand on the quality of research they are able to conduct. In South America and Antarctica, AirSAR collected imagery and data to help determine the contribution of Southern Hemisphere glaciers to sea level rise due to climate change. In Patagonia, researchers found this contribution had more than doubled from 1995 to 2000, compared to the previous 25 years. AirSAR data will make it possible to determine whether that trend is continuing or accelerating. AirSAR will also provide reliable information on ice shelf thickness to measure the contribution of the glaciers to sea level.
NASA Technical Reports Server (NTRS)
Rignot, E.; Chellappa, R.
1993-01-01
We present a maximum a posteriori (MAP) classifier for classifying multifrequency, multilook, single polarization SAR intensity data into regions or ensembles of pixels of homogeneous and similar radar backscatter characteristics. A model for the prior joint distribution of the multifrequency SAR intensity data is combined with a Markov random field for representing the interactions between region labels to obtain an expression for the posterior distribution of the region labels given the multifrequency SAR observations. The maximization of the posterior distribution yields Bayes's optimum region labeling or classification of the SAR data or its MAP estimate. The performance of the MAP classifier is evaluated by using computer-simulated multilook SAR intensity data as a function of the parameters in the classification process. Multilook SAR intensity data are shown to yield higher classification accuracies than one-look SAR complex amplitude data. The MAP classifier is extended to the case in which the radar backscatter from the remotely sensed surface varies within the SAR image because of incidence angle effects. The results obtained illustrate the practicality of the method for combining SAR intensity observations acquired at two different frequencies and for improving classification accuracy of SAR data.
Receptor-binding domain as a target for developing SARS vaccines.
Zhu, Xiaojie; Liu, Qi; Du, Lanying; Lu, Lu; Jiang, Shibo
2013-08-01
A decade ago, severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) caused a global pandemic with a mortality rate of 10%. Reports of recent outbreaks of a SARS-like disease caused by Middle East respiratory syndrome coronavirus (MERS-CoV) have raised serious concerns of a possible reemergence of SARS-CoV, either by laboratory escape or the presence of a natural reservoir. Therefore, the development of effective and safe SARS vaccines is still needed. Based on our previous studies, we believe that the receptor-binding domain (RBD) in the S1 subunit of the SARS-CoV spike (S) protein is the most important target for developing a SARS vaccine. In particular, RBD of S protein contains the critical neutralizing domain (CND), which is able to induce highly potent neutralizing antibody response and cross-protection against divergent SARS-CoV strains. Furthermore, a RBD-based subunit vaccine is expected to be safer than other vaccines that may induce Th2-type immunopathology. This review will discuss key advances in the development of RBD-based SARS vaccines and the possibility of using a similar strategy to develop vaccines against MERS-CoV.
Glowacka, Ilona; Bertram, Stephanie; Müller, Marcel A.; Allen, Paul; Soilleux, Elizabeth; Pfefferle, Susanne; Steffen, Imke; Tsegaye, Theodros Solomon; He, Yuxian; Gnirss, Kerstin; Niemeyer, Daniela; Schneider, Heike; Drosten, Christian; Pöhlmann, Stefan
2011-01-01
The spike (S) protein of the severe acute respiratory syndrome coronavirus (SARS-CoV) can be proteolytically activated by cathepsins B and L upon viral uptake into target cell endosomes. In contrast, it is largely unknown whether host cell proteases located in the secretory pathway of infected cells and/or on the surface of target cells can cleave SARS S. We along with others could previously show that the type II transmembrane protease TMPRSS2 activates the influenza virus hemagglutinin and the human metapneumovirus F protein by cleavage. Here, we assessed whether SARS S is proteolytically processed by TMPRSS2. Western blot analysis revealed that SARS S was cleaved into several fragments upon coexpression of TMPRSS2 (cis-cleavage) and upon contact between SARS S-expressing cells and TMPRSS2-positive cells (trans-cleavage). cis-cleavage resulted in release of SARS S fragments into the cellular supernatant and in inhibition of antibody-mediated neutralization, most likely because SARS S fragments function as antibody decoys. trans-cleavage activated SARS S on effector cells for fusion with target cells and allowed efficient SARS S-driven viral entry into targets treated with a lysosomotropic agent or a cathepsin inhibitor. Finally, ACE2, the cellular receptor for SARS-CoV, and TMPRSS2 were found to be coexpressed by type II pneumocytes, which represent important viral target cells, suggesting that SARS S is cleaved by TMPRSS2 in the lung of SARS-CoV-infected individuals. In summary, we show that TMPRSS2 might promote viral spread and pathogenesis by diminishing viral recognition by neutralizing antibodies and by activating SARS S for cell-cell and virus-cell fusion. PMID:21325420
Seng, S L; Lim, P S; Ng, M Y; Wong, H B; Emmanuel, S C
2004-09-01
The study aimed to assess the effectiveness of massive SARS public education effort on SARS awareness and the conduct of those suspected of having SARS. Five hundred and ninety-three respondents attending the National Healthcare Group Polyclinics (NHGP) participated in the survey from 9 to 13 June 2003. Associations between awareness of SARS symptoms and (i) first action to be taken and (ii) mode of transportation used, if the respondent was suspected of having SARS, were analysed using Chi-square or Fisher's exact tests. Logistic regression was performed to adjust for relevant covariates. The majority (92.7%) of the respondents were aware of SARS symptoms. Television (91.6%), newspaper (65.2%) and radio (30.4%) formed the top 3 sources of information on SARS. Slightly more than half (51.6%) of those who suspect themselves of having SARS would choose to visit their primary health care doctors, while 22.7% of the respondents would go to Tan Tock Seng Hospital (TTSH). If they suspected themselves to have SARS, most (84.9%) of the 578 respondents would react appropriately by taking the SARS ambulance or driving themselves to TTSH. However, 60 respondents would nonetheless take public transport to TTSH [by taxi 8.5%, mass rapid transit (MRT) or bus 1.9%]. In particular, the retired with lower educational levels were likely to be oblivious both to the symptoms of SARS and the possible consequences of travelling by inappropriate transport. Despite more than 2 months of intensive SARS public education in Singapore, there remain important gaps in knowledge and appropriate behaviour that have to be bridged.
Segmentation of oil spills in SAR images by using discriminant cuts
NASA Astrophysics Data System (ADS)
Ding, Xianwen; Zou, Xiaolin
2018-02-01
The discriminant cut is used to segment the oil spills in synthetic aperture radar (SAR) images. The proposed approach is a region-based one, which is able to capture and utilize spatial information in SAR images. The real SAR images, i.e. ALOS-1 PALSAR and Sentinel-1 SAR images were collected and used to validate the accuracy of the proposed approach for oil spill segmentation in SAR images. The accuracy of the proposed approach is higher than that of the fuzzy C-means classification method.
Air pollution and case fatality of SARS in the People's Republic of China: an ecologic study
Cui, Yan; Zhang, Zuo-Feng; Froines, John; Zhao, Jinkou; Wang, Hua; Yu, Shun-Zhang; Detels, Roger
2003-01-01
Background Severe acute respiratory syndrome (SARS) has claimed 349 lives with 5,327 probable cases reported in mainland China since November 2002. SARS case fatality has varied across geographical areas, which might be partially explained by air pollution level. Methods Publicly accessible data on SARS morbidity and mortality were utilized in the data analysis. Air pollution was evaluated by air pollution index (API) derived from the concentrations of particulate matter, sulfur dioxide, nitrogen dioxide, carbon monoxide and ground-level ozone. Ecologic analysis was conducted to explore the association and correlation between air pollution and SARS case fatality via model fitting. Partially ecologic studies were performed to assess the effects of long-term and short-term exposures on the risk of dying from SARS. Results Ecologic analysis conducted among 5 regions with 100 or more SARS cases showed that case fatality rate increased with the increment of API (case fatality = - 0.063 + 0.001 * API). Partially ecologic study based on short-term exposure demonstrated that SARS patients from regions with moderate APIs had an 84% increased risk of dying from SARS compared to those from regions with low APIs (RR = 1.84, 95% CI: 1.41–2.40). Similarly, SARS patients from regions with high APIs were twice as likely to die from SARS compared to those from regions with low APIs. (RR = 2.18, 95% CI: 1.31–3.65). Partially ecologic analysis based on long-term exposure to ambient air pollution showed the similar association. Conclusion Our studies demonstrated a positive association between air pollution and SARS case fatality in Chinese population by utilizing publicly accessible data on SARS statistics and air pollution indices. Although ecologic fallacy and uncontrolled confounding effect might have biased the results, the possibility of a detrimental effect of air pollution on the prognosis of SARS patients deserves further investigation. PMID:14629774
NASA Astrophysics Data System (ADS)
Martínez-Búrdalo, M.; Martín, A.; Anguiano, M.; Villar, R.
2004-01-01
In this paper, the specific absorption rate (SAR) in scaled human head models is analysed to study possible differences between SAR in the heads of adults and children and for assessment of compliance with the international safety guidelines, while using a mobile phone. The finite-difference time-domain method (FDTD) has been used for calculating SAR values for models of both children and adults, at 900 and 1800 MHz. Maximum 1 g averaged SAR (SAR1 g) and maximum 10 g averaged SAR (SAR10 g) have been calculated in adults and scaled head models for comparison and assessment of compliance with ANSI/IEEE and European guidelines. Results show that peak SAR1 g and peak SAR10 g all trend downwards with decreasing head size but as head size decreases, the percentage of energy absorbed in the brain increases. So, higher SAR in children's brains can be expected depending on whether the thickness of their skulls and surrounding tissues actually depends on age. The SAR in eyes of different sizes, as a critical organ, has also been studied and very similar distributions for the full size and the scaled models have been obtained. Standard limits can only be exceeded in the unpractical situation where the antenna is located at a very short distance in front of the eye.
O'Keefe, Barry R.; Giomarelli, Barbara; Barnard, Dale L.; Shenoy, Shilpa R.; Chan, Paul K. S.; McMahon, James B.; Palmer, Kenneth E.; Barnett, Brian W.; Meyerholz, David K.; Wohlford-Lenane, Christine L.; McCray, Paul B.
2010-01-01
Viruses of the family Coronaviridae have recently emerged through zoonotic transmission to become serious human pathogens. The pathogenic agent responsible for severe acute respiratory syndrome (SARS), the SARS coronavirus (SARS-CoV), is a member of this large family of positive-strand RNA viruses that cause a spectrum of disease in humans, other mammals, and birds. Since the publicized outbreaks of SARS in China and Canada in 2002-2003, significant efforts successfully identified the causative agent, host cell receptor(s), and many of the pathogenic mechanisms underlying SARS. With this greater understanding of SARS-CoV biology, many researchers have sought to identify agents for the treatment of SARS. Here we report the utility of the potent antiviral protein griffithsin (GRFT) in the prevention of SARS-CoV infection both in vitro and in vivo. We also show that GRFT specifically binds to the SARS-CoV spike glycoprotein and inhibits viral entry. In addition, we report the activity of GRFT against a variety of additional coronaviruses that infect humans, other mammals, and birds. Finally, we show that GRFT treatment has a positive effect on morbidity and mortality in a lethal infection model using a mouse-adapted SARS-CoV and also specifically inhibits deleterious aspects of the host immunological response to SARS infection in mammals. PMID:20032190
NASA Astrophysics Data System (ADS)
Changyong, Dou; Huadong, Guo; Chunming, Han; yuquan, Liu; Xijuan, Yue; Yinghui, Zhao
2014-03-01
Raw signal simulation is a useful tool for the system design, mission planning, processing algorithm testing, and inversion algorithm design of Synthetic Aperture Radar (SAR). Due to the wide and high frequent variation of aircraft's trajectory and attitude, and the low accuracy of the Position and Orientation System (POS)'s recording data, it's difficult to quantitatively study the sensitivity of the key parameters, i.e., the baseline length and inclination, absolute phase and the orientation of the antennas etc., of the airborne Interferometric SAR (InSAR) system, resulting in challenges for its applications. Furthermore, the imprecise estimation of the installation offset between the Global Positioning System (GPS), Inertial Measurement Unit (IMU) and the InSAR antennas compounds the issue. An airborne interferometric SAR (InSAR) simulation based on the rigorous geometric model and real navigation data is proposed in this paper, providing a way for quantitatively studying the key parameters and for evaluating the effect from the parameters on the applications of airborne InSAR, as photogrammetric mapping, high-resolution Digital Elevation Model (DEM) generation, and surface deformation by Differential InSAR technology, etc. The simulation can also provide reference for the optimal design of the InSAR system and the improvement of InSAR data processing technologies such as motion compensation, imaging, image co-registration, and application parameter retrieval, etc.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wahl, D.E.; Jakowatz, C.V. Jr.; Ghiglia, D.C.
1991-01-01
Autofocus methods in SAR and self-survey techniques in SONAR have a common mathematical basis in that they both involve estimation and correction of phase errors introduced by sensor position uncertainties. Time delay estimation and correlation methods have been shown to be effective in solving the self-survey problem for towed SONAR arrays. Since it can be shown that platform motion errors introduce similar time-delay estimation problems in SAR imaging, the question arises as to whether such techniques could be effectively employed for autofocus of SAR imagery. With a simple mathematical model for motion errors in SAR, we will show why suchmore » correlation/time-delay techniques are not nearly as effective as established SAR autofocus algorithms such as phase gradient autofocus or sub-aperture based methods. This analysis forms an important bridge between signal processing methodologies for SAR and SONAR. 5 refs., 4 figs.« less
A New SAR Image Segmentation Algorithm for the Detection of Target and Shadow Regions
Huang, Shiqi; Huang, Wenzhun; Zhang, Ting
2016-01-01
The most distinctive characteristic of synthetic aperture radar (SAR) is that it can acquire data under all weather conditions and at all times. However, its coherent imaging mechanism introduces a great deal of speckle noise into SAR images, which makes the segmentation of target and shadow regions in SAR images very difficult. This paper proposes a new SAR image segmentation method based on wavelet decomposition and a constant false alarm rate (WD-CFAR). The WD-CFAR algorithm not only is insensitive to the speckle noise in SAR images but also can segment target and shadow regions simultaneously, and it is also able to effectively segment SAR images with a low signal-to-clutter ratio (SCR). Experiments were performed to assess the performance of the new algorithm on various SAR images. The experimental results show that the proposed method is effective and feasible and possesses good characteristics for general application. PMID:27924935
Anti–SARS-CoV Immunoglobulin G in Healthcare Workers, Guangzhou, China
Lu, Ci-Yong; Wong, Tze-Wai; Ling, Wen-Hua; Lin, Zhong-Ning; Hao, Yuan-Tao; Liu, Qing; Fang, Ji-Qian; He, Yun; Luo, Fu-Tian; Jing, Jin; Ling, Li; Ma, Xiang; Liu, Yi-Min; Chen, Gui-Hua; Huang, Jian; Jiang, Yuan-Sen; Jiang, Wen-Qi; Zou, He-Qun; Yan, Guang-Mei
2005-01-01
To determine the prevalence of inapparent infection with severe acute respiratory syndrome (SARS) among healthcare workers, we performed a serosurvey to test for immunoglobulin (Ig) G antibodies to the SARS coronavirus (SARS-CoV) among 1,147 healthcare workers in 3 hospitals that admitted SARS patients in mid-May 2003. Among them were 90 healthcare workers with SARS. As a reference group, 709 healthcare workers who worked in 2 hospitals that never admitted any SARS patients were similarly tested. The seroprevalence rate was 88.9% (80/90) for healthcare workers with SARS and 1.4% (15/1,057) for healthcare workers who were apparently healthy. The seroprevalence in the reference group was 0.4% (3/709). These findings suggest that inapparent infection is uncommon. Low level of immunity among unaffected healthcare workers reinforces the need for adequate personal protection and other infection control measures in hospitals to prevent future epidemics. PMID:15705328
A New SAR Image Segmentation Algorithm for the Detection of Target and Shadow Regions.
Huang, Shiqi; Huang, Wenzhun; Zhang, Ting
2016-12-07
The most distinctive characteristic of synthetic aperture radar (SAR) is that it can acquire data under all weather conditions and at all times. However, its coherent imaging mechanism introduces a great deal of speckle noise into SAR images, which makes the segmentation of target and shadow regions in SAR images very difficult. This paper proposes a new SAR image segmentation method based on wavelet decomposition and a constant false alarm rate (WD-CFAR). The WD-CFAR algorithm not only is insensitive to the speckle noise in SAR images but also can segment target and shadow regions simultaneously, and it is also able to effectively segment SAR images with a low signal-to-clutter ratio (SCR). Experiments were performed to assess the performance of the new algorithm on various SAR images. The experimental results show that the proposed method is effective and feasible and possesses good characteristics for general application.
SARS-CoV Infection in a Restaurant from Palm Civet
Wang, Ming; Yan, Meiying; Xu, Huifang; Liang, Weili; Kan, Biao; Zheng, Bojian; Chen, Honglin; Zheng, Han; Xu, Yanmei; Zhang, Enmin; Wang, Hongxia; Ye, Jingrong; Li, Guichang; Li, Machao; Cui, Zhigang; Liu, Yu-Fei; Guo, Rong-Tong; Liu, Xiao-Ning; Zhan, Liu-Hua; Zhou, Duan-Hua; Zhao, Ailan; Hai, Rong; Yu, Dongzhen; Guan, Yi
2005-01-01
Epidemiologic investigations showed that 2 of 4 patients with severe acute respiratory syndrome (SARS) identified in the winter of 2003–2004 were a waitress at a restaurant in Guangzhou, China, that served palm civets as food and a customer who ate in the restaurant a short distance from animal cages. All 6 palm civets at the restaurant were positive for SARS-associated coronavirus (SARS-CoV). Partial spike (S) gene sequences of SARS-CoV from the 2 patients were identical to 4 of 5 S gene viral sequences from palm civets. Phylogenetic analysis showed that SARS-CoV from palm civets in the restaurant was most closely related to animal isolates. SARS cases at the restaurant were the result of recent interspecies transfer from the putative palm civet reservoir, and not the result of continued circulation of SARS-CoV in the human population. PMID:16485471
SARS-CoV infection in a restaurant from palm civet.
Wang, Ming; Yan, Meiying; Xu, Huifang; Liang, Weili; Kan, Biao; Zheng, Bojian; Chen, Honglin; Zheng, Han; Xu, Yanmei; Zhang, Enmin; Wang, Hongxia; Ye, Jingrong; Li, Guichang; Li, Machao; Cui, Zhigang; Liu, Yu-Fei; Guo, Rong-Tong; Liu, Xiao-Ning; Zhan, Liu-Hua; Zhou, Duan-Hua; Zhao, Ailan; Hai, Rong; Yu, Dongzhen; Guan, Yi; Xu, Jianguo
2005-12-01
Epidemiologic investigations showed that 2 of 4 patients with severe acute respiratory syndrome (SARS) identified in the winter of 2003-2004 were a waitresss at a restaurant in Guangzhou, China, that served palm civets as food and a customer who ate in the restaurant ashort distance from animal cages. All 6 palm civets at the restaurant were positive for SARS-associated coronavirus (SARS-CoV). Partial spike (S) gene sequences of SARS-CoV from the 2 patients were identical to 4 of 5 Sgene viral sequences from palm civets. Phylogenetic analysis showed that SARS-CoV from palm civets in the restaurant was most closely related to animal isolates. SARS cases at the restaurant were the result of recent interspecies transfer from the putative palm civet reservoir, and not the result of continued circulation of SARS-CoV in the human population.
Kitabatake, Masahiro; Inoue, Shingo; Yasui, Fumihiko; Yokochi, Shoji; Arai, Masaaki; Morita, Kouichi; Shida, Hisatoshi; Kidokoro, Minoru; Murai, Fukashi; Le, Mai Quynh; Mizuno, Kyosuke; Matsushima, Kouji; Kohara, Michinori
2007-01-08
A vaccine for severe acute respiratory syndrome (SARS) is being intensively pursued against its re-emergence. We generated a SARS coronavirus (SARS-CoV) spike protein-expressing recombinant vaccinia virus (RVV-S) using highly attenuated strain LC16m8. Intradermal administration of RVV-S into rabbits induced neutralizing (NT) antibodies against SARS-CoV 1 week after administration and the NT titer reached 1:1000 after boost immunization with RVV-S. Significantly, NT antibodies against SARS-CoV were induced by administration of RVV-S to rabbits that had been pre-immunized with LC16m8. RVV-S can induce NT antibodies against SARS-CoV despite the presence of NT antibodies against VV. These results suggest that RVV-S may be a powerful SARS vaccine, including in patients previously immunized with the smallpox vaccine.
PRF Ambiguity Detrmination for Radarsat ScanSAR System
NASA Technical Reports Server (NTRS)
Jin, Michael Y.
1998-01-01
PRF ambiguity is a potential problem for a spaceborne SAR operated at high frequencies. For a strip mode SAR, there were several approaches to solve this problem. This paper, however, addresses PRF ambiguity determination algorithms suitable for a burst mode SAR system such as the Radarsat ScanSAR. The candidate algorithms include the wavelength diversity algorithm, range look cross correlation algorithm, and multi-PRF algorithm.
Method for removing RFI from SAR images
Doerry, Armin W.
2003-08-19
A method of removing RFI from a SAR by comparing two SAR images on a pixel by pixel basis and selecting the pixel with the lower magnitude to form a composite image. One SAR image is the conventional image produced by the SAR. The other image is created from phase-history data which has been filtered to have the frequency bands containing the RFI removed.
NASA Astrophysics Data System (ADS)
Yague-Martinez, N.; Fielding, E. J.; Haghshenas-Haghighi, M.; Cong, X.; Motagh, M.
2014-12-01
This presentation will address the 24 September 2013 Mw 7.7 Balochistan Earthquake in western Pakistan from the point of view of interferometric processing algorithms of wide-swath TerraSAR-X ScanSAR images. The algorithms are also valid for TOPS acquisition mode, the operational mode of the Sentinel-1A ESA satellite that was successfully launched in April 2014. Spectral properties of burst-mode data and an overview of the interferometric processing steps of burst-mode acquisitions, emphasizing the importance of the co-registration stage, will be provided. A co-registration approach based on incoherent cross-correlation will be presented and applied to seismic scenarios. Moreover geodynamic corrections due to differential atmospheric path delay and differential solid Earth tides are considered to achieve accuracy in the order of several centimeters. We previously derived a 3D displacement map using cross-correlation techniques applied to optical images from Landsat-8 satellite and TerraSAR-X ScanSAR amplitude images. The Landsat-8 cross-correlation measurements cover two horizontal directions, and the TerraSAR-X displacements include both horizontal along-track and slant-range (radar line-of-sight) measurements that are sensitive to vertical and horizontal deformation. It will be justified that the co-seismic displacement map from TerraSAR-X ScanSAR data may be contaminated by postseismic deformation due to the fact that the post-seismic acquisition took place one month after the main shock, confirmed in part by a TerraSAR-X stripmap interferogram (processed with conventional InSAR) covering part of the area starting on 27 September 2013. We have arranged the acquisition of a burst-synchronized stack of TerraSAR-X ScanSAR images over the affected area after the earthquake. It will be possible to apply interferometry to these data to measure the lower magnitude of the expected postseismic displacements. The processing of single interferograms will be discussed. A quicklook of the wrapped differential TerraSAR-X ScanSAR co-seismic interferogram is provided in the attachment (range coverage is 100 km by using 4 subswaths).
Seismic rupture process of the 2010 Haiti Earthquake (Mw7.0) inferred from seismic and SAR data
NASA Astrophysics Data System (ADS)
Santos, Rúben; Caldeira, Bento; Borges, José; Bezzeghoud, Mourad
2013-04-01
On January 12th 2010 at 21:53, the Port-au-Prince - Haiti region was struck by an Mw7 earthquake, the second most deadly of the history. The last seismic significant events in the region occurred in November 1751 and June 1770 [1]. Geodetic and geological studies, previous to the 2010 earthquake [2] have warned to the potential of the destructive seismic events in that region and this event has confirmed those warnings. Some aspects of the source of this earthquake are nonconsensual. There is no agreement in the mechanism of rupture or correlation with the fault that should have it generated [3]. In order to better understand the complexity of this rupture, we combined several techniques and data of different nature. We used teleseismic body-wave and Synthetic Aperture Radar data (SAR) based on the following methodology: 1) analysis of the rupture process directivity [4] to determine the velocity and direction of rupture; 2) teleseismic body-wave inversion to obtain the spatiotemporal fault slip distribution and a detailed rupture model; 3) near field surface deformation modeling using the calculated seismic rupture model and compared with the measured deformation field using SAR data of sensor Advanced Land Observing Satellite - Phased Array L-band SAR (ALOS-PALSAR). The combined application of seismic and geodetic data reveals a complex rupture that spread during approximately 12s mainly from WNW to ESE with average velocity of 2,5km/s, on a north-dipping fault plane. Two main asperities are obtained: the first (and largest) occurs within the first ~ 5sec and extends for approximately 6km around the hypocenter; the second one, that happens in the remaining 6s, covers a near surface rectangular strip with about 12km long by 3km wide. The first asperity is compatible with a left lateral strike-slip motion with a small reverse component; the mechanism of second asperity is predominantly reverse. The obtained rupture process allows modeling a coseismic deformation which is in agreement with the deformation field measured by InSAR. [1] Bakun W, Flores C, Brink U, 2012 Significant Earthquakes on the Enriquillo Fault System, Hispaniola, 1500-2010: Implications for Seismic Hazard. Bul. Seis. Soc. of America, 102(1):18-30. [2] Dixon, T. et al., 1998. Relative motion between the Caribbean and North American plates and related boundary zone deformation based on a decade of GPS observations. J. Geophys. Res. 103, 15157-15182. [3] Mercier de Lépinay, B., Deschamps, A., Klingelhoefer, F., Mazabraud, Y., Delouis, B., Clouard, V., Hello Y., Crozon, J., Marcaillou, B., Graindorge, D., Vallée M., Perrot, J., Bouin, M., Saurel, J., Charvis, Philippe, C. and St-Louis, 2011. The 2010 Haiti earthquake: A complex fault pattern constrained by seismologic and tectonic observations, Geoph. Res. Let., 30, L22305 [4] Caldeira B, Bezzeghoud M, Borges JF., 2009 DIRDOP: a directivity approach to determining the seismic rupture velocity vector. J. of Seis.. 2009;14(3):565-600.
Infectivity of severe acute respiratory syndrome during its incubation period.
Zeng, Guang; Xie, Shu-Yun; Li, Qin; Ou, Jian-Ming
2009-12-01
To evaluate the infectivity of severe acute respiratory syndrome (SARS) during its incubation period by investigating chains of transmission and individuals isolated for medical observation with a view to providing scientific evidence for updating protocols of medical isolation. Individuals related with the two SARS chains of transmission in Beijing in 2003 and a group of individuals isolated for medical observation in Haidian district of Beijing during the SARS outbreak were selected as subjects of study. Contactors with SARS patients and those with symptom development following the contacts were investigated via questionnaire. Serum samples were collected from super transmitters and tested for SARS-CoV antibody by neutralization test and enzyme linked immunosorbent assay (ELISA). A total of 1112 contactors were investigated in three surveys. Of them, 669 had a history of close contact with symptomatic SARS patients, 101 developed symptoms with a rate of 15.1%, 363 had a history of close contact with patients in their incubation period, none of whom developed symptoms (0%). Serum samples were collected from 32 highly-exposed individuals, of whom 13 developing SARS symptoms after contact had serum samples positive for SARS-CoV antibody. Samples collected from the asymptomatic contactors were all negative for SARS-CoV antibody. SARS cases are infectious only during their symptomatic period and are non-infectious during the incubation period. Isolation for medical observation should be placed for individuals who are in close contact with symptomatic SARS patients. The results of our study are of decisive significance for the Ministry of Health to the definition of SARS close contactor.
Land subsidence monitoring in central Taiwan by using PS-InSAR technique
NASA Astrophysics Data System (ADS)
Hu, J.-C.; Tung, H.; Huang, M.-H.
2009-04-01
Ground subsidence induced by heavy withdrawal of underground water has resulted in environmental hazard and potential risk in Taiwan, particularly in the Choushui River alluvial fan where the Yunlin section of the Taiwan High Speed Rail had been constructed. The Yunlin County located in the southwestern coastal region of Taiwan is one of the most counties with serious land subsidence because of the agricultural needs. Yunlin County is one of the important agricultural production regions located in the southwestern coastal region of Taiwan where the irrigated area is up to 123,000 hectares and agricultural water consumption reaches approximate 90 percents of all available water resources in the Choshui River Basin. Moreover, since there is no sufficient surface water supplied, groundwater becomes a vital resource for every water consumption targets. Seasonal effects of land subsidence occurring in the study area had been estimated using a regression analysis of a series of weekly GPS height solutions. These results demonstrated the average rate of ground subsidence in this area over the period of 1995-2001 was 3 cm/yr. Based on data collected at the piezometer, the variation of land subsidence rate appears to be associated with an unstable underground water level, which drop gradually during winter and either remains constant or rises during summer time. Consequently, land subsidence rates vary considerably from 1.5 cm/yr for the summer time to 9.0 cm/yr for the winter time. In addition, anthropogenic ground subsidence due to massive pumping of groundwater is one of problems in Taiwan. In this study, we represented a both stacking D-InSAR and PS-InSAR results deduced from 1996-1999 time spans for monitoring of land subsidence in this area. Both D-InSAR and PS-InSAR results show the Baojhou, Tuku Township and northern Mailiao reveal a maximum subsidence rate of about 6 cm/yr along LOS and the Taishi Township located on the coastal area reveals a subsidence rate of 1.6 cm/yr, which is quite coincident with precise leveling result. These two results have proven that the effective reduction of labor and cost could be achieved by using this technique on monitoring land subsidence in Yunlin County.
NASA Astrophysics Data System (ADS)
Frodella, William; Pazzi, Veronica; Morelli, Stefano; Salvatici, Teresa; Fanti, Riccardo
2017-04-01
Between October 31st and November 2nd 2010 the whole Veneto region (north-eastern Italy) was hit by heavy and persistent rainfall, which diffusely triggered floods and slope failures. In this framework on November 4th 2010 a detrital mass, approximately 225.000 m3 in volume, detached from the lowermost sector of the Mt. Rotolon landslide cover (located in the Vicentine Pre-Alps, upper Agno River Valley), channelizing within the Rotolon Creek riverbed and evolving into a highly mobile debris flow. The latter phenomena, characterized by a 3 km travel distance, damaged many hydraulic works, putting at high risk bridges and local roads located along the creek banks, together with the population of both the town of Recoaro Terme and the villages of Maltaure, Turcati and Parlati. Starting from the beginning of the emergency phase, the Civil Protection system was activated, involving the National Civil Protection Department, Veneto Region and local administrations personnel and technicians, as well as research centers. On December 8th 2010 a local scale monitoring system, based on a ground based interferometric radar (GB-InSAR), was implemented in order to evaluate the slope deformation pattern evolution in correspondence of the debris flow detachment sector, with the final aim of assessing the landslide residual risk and manage the emergency phase. Accurate geomorphological field surveys were also carried out, in order to study the landslide morphological features as to improve the radar data interpretation. The radar system acquired in continuous GB-InSAR data, such as displacement maps and time series of 10 selected monitoring points, which were uploaded via LAN network on a dedicated Web-based interface, shared with the technical stakeholders and decision makers involved in the emergency management and allowing for a near real time data routine visualization. This paper describes the outcomes of a 2 years GB-InSAR monitoring campaign (December 2010-November 2012), reporting the various applications of GB-InSAR data for monitoring, mapping and emergency management activities, in order to provide a rapid and easy communication of the results to the involved technicians and civil protection personnel, for a better understanding of the landslide phenomena and decision making process in a critical landslide scenario.
Shearn, Rylan; Halse, Stuart; Koenders, Annette; Schön, Isa; Martens, Koen
2014-10-23
In this paper, we redescribe six species of the genus Ilyodromus Sars, 1894: I, stanleyanus (King, 1855), I. varrovillius (King, 1855), I. smaragdinus Sars, 1894, I. obtusus Sars, 1894, I. substriatus Sars, 1894 and I. viridulus (Brady, 1886) using materials stored in the Oslo museum (Norway) and (re-) described by G.O. Sars. For each species examined, we have identified a number of additional diagnostic characters to those used by Sars and earlier authors. In particular, the length of setae, claws and segments of the antennule, antenna, sixth limb, and caudal ramus appear to be important for species delineation in the genus, as does the internal structure of the valves.
2004-03-03
Personnel viewing AirSAR hardware while touring the outside of NASA's DC-8 during a stop-off on the AirSAR 2004 Mesoamerica campaign, L-R: Fernando Gutierrez, Costa Rican Minister of Science and Technology(MICIT); NASA Administrator Sean O'Keefe; Dr. Gahssem Asrar, NASA Associate Administrator for Earth Science Enterprises; JPL scientist Bruce Chapman; and Craig Dobson, NASA Program Manager for AirSAR. AirSAR 2004 Mesoamerica is a three-week expedition by an international team of scientists that will use an all-weather imaging tool, called the Airborne Synthetic Aperture Radar (AirSAR), in a mission ranging from the tropical rain forests of Central America to frigid Antarctica.
Risk Factors for SARS among Persons without Known Contact with SARS Patients, Beijing, China
Wu, Jiang; Xu, Fujie; Zhou, Weigong; Feikin, Daniel R.; Lin, Chang-Ying; He, Xiong; Zhu, Zonghan; Liang, Wannian; Chin, Daniel P.
2004-01-01
Most cases of severe acute respiratory syndrome (SARS) have occurred in close contacts of SARS patients. However, in Beijing, a large proportion of SARS cases occurred in persons without such contact. We conducted a case-control study in Beijing that compared exposures of 94 unlinked, probable SARS patients with those of 281 community-based controls matched for age group and sex. Case-patients were more likely than controls to have chronic medical conditions or to have visited fever clinics (clinics at which possible SARS patients were separated from other patients), eaten outside the home, or taken taxis frequently. The use of masks was strongly protective. Among 31 case-patients for whom convalescent-phase (>21 days) sera were available, 26% had immunoglobulin G to SARS-associated coronavirus. Our finding that clinical SARS was associated with visits to fever clinics supports Beijing’s strategy of closing clinics with poor infection-control measures. Our finding that mask use lowered the risk for disease supports the community’s use of this strategy. PMID:15030685
Yasui, Fumihiko; Kohara, Michinori; Kitabatake, Masahiro; Nishiwaki, Tetsu; Fujii, Hideki; Tateno, Chise; Yoneda, Misako; Morita, Kouichi; Matsushima, Kouji; Koyasu, Shigeo; Kai, Chieko
2014-04-01
While the 2002-2003 outbreak of severe acute respiratory syndrome (SARS) resulted in 774 deaths, patients who were affected with mild pulmonary symptoms successfully recovered. The objective of the present work was to identify, using SARS coronavirus (SARS-CoV) mouse infection models, immune factors responsible for clearing of the virus. The elimination of pulmonary SARS-CoV infection required the activation of B cells by CD4(+) T cells. Furthermore, passive immunization (post-infection) with homologous (murine) anti-SARS-CoV antiserum showed greater elimination efficacy against SARS-CoV than that with heterologous (rabbit) antiserum, despite the use of equivalent titers of neutralizing antibodies. This distinction was mediated by mouse phagocytic cells (monocyte-derived infiltrating macrophages and partially alveolar macrophages, but not neutrophils), as demonstrated both by adoptive transfer from donors and by immunological depletion of selected cell types. These results indicate that the cooperation of anti-SARS-CoV antibodies and phagocytic cells plays an important role in the elimination of SARS-CoV. Copyright © 2014 Elsevier Inc. All rights reserved.
A unified theory of stable auroral red arc formation at the plasmapause
NASA Technical Reports Server (NTRS)
Cornwall, J. M.; Coroniti, F. V.; Thorne, R. M.
1970-01-01
A theory is proposed that SAR-arcs are generated at the plasmapause as a consequence of the turbulent dissipation of ring current energy. During the recovery phase of a geomagnetic storm, the plasmapause expands outward into the symmetric ring current. When the cold plasma densities reach about 100/cu cm, ring current protons become unstable and generate intense ion cyclotron wave turbulence in a narrow region 1/2 earth radius wide (just inside the plasmapause). Approximately one-half of the ring current energy is dissipated into wave turbulence which in turn is absorbed through a Landau resonant interaction with plasma spheric electrons. The combined thermal heat flux to the ionosphere due to Landau absorption of the wave energy and proton-electron Coulomb dissipation is sufficient to drive SAR-arcs at the observed intensities. It is predicted that the arcs should be localized to a narrow latitudinal range just within the stormtime plasmapause. They should occur at all local times and persist for the 10 to 20 hour duration of the plasma-pause expansion.
Differential nuclear scaffold/matrix attachment marks expressed genes.
Linnemann, Amelia K; Platts, Adrian E; Krawetz, Stephen A
2009-02-15
It is well established that nuclear architecture plays a key role in poising regions of the genome for transcription. This may be achieved using scaffold/matrix attachment regions (S/MARs) that establish loop domains. However, the relationship between changes in the physical structure of the genome as mediated by attachment to the nuclear scaffold/matrix and gene expression is not clearly understood. To define the role of S/MARs in organizing our genome and to resolve the often contradictory loci-specific studies, we have surveyed the S/MARs in HeLa S3 cells on human chromosomes 14-18 by array comparative genomic hybridization. Comparison of LIS (lithium 3,5-diiodosalicylate) extraction to identify SARs and 2 m NaCl extraction to identify MARs revealed that approximately one-half of the sites were in common. The results presented in this study suggest that SARs 5' of a gene are associated with transcript presence whereas MARs contained within a gene are associated with silenced genes. The varied functions of the S/MARs as revealed by the different extraction methods highlights their unique functional contribution.
Differential nuclear scaffold/matrix attachment marks expressed genes†
Linnemann, Amelia K.; Platts, Adrian E.; Krawetz, Stephen A.
2009-01-01
It is well established that nuclear architecture plays a key role in poising regions of the genome for transcription. This may be achieved using scaffold/matrix attachment regions (S/MARs) that establish loop domains. However, the relationship between changes in the physical structure of the genome as mediated by attachment to the nuclear scaffold/matrix and gene expression is not clearly understood. To define the role of S/MARs in organizing our genome and to resolve the often contradictory loci-specific studies, we have surveyed the S/MARs in HeLa S3 cells on human chromosomes 14–18 by array comparative genomic hybridization. Comparison of LIS (lithium 3,5-diiodosalicylate) extraction to identify SARs and 2 m NaCl extraction to identify MARs revealed that approximately one-half of the sites were in common. The results presented in this study suggest that SARs 5′ of a gene are associated with transcript presence whereas MARs contained within a gene are associated with silenced genes. The varied functions of the S/MARs as revealed by the different extraction methods highlights their unique functional contribution. PMID:19017725
Bawden, Gerald W.; Johnson, Michaela R.; Kasmarek, Mark C.; Brandt, Justin; Middleton, Clifton S.
2012-01-01
The interferograms show that the area of historical subsidence in downtown Houston along the Houston Ship Channel has stabilized and that recent subsidence occurs farther west and north of Galveston Bay. Three areas of recent subsidence were delineated along a broad arcuate (bowshaped) feature from Spring, Tex., southwest to Cypress, Tex., and south to Sugar Land, Tex., with subsidence rates ranging from 15 millimeters per year (mm/yr) to greater than 60 mm/yr. Multiyear interferograms near Seabrook, Tex., within the historical subsidence area and nearby Galveston Bay, show several fringes of subsidence (approximately 85 millimeters from January 1996 to December 1997) in the area; however it is difficult to determine the subsidence magnitude near Seabrook because many of the InSAR fringes were truncated or ill-defined. Horizontal and vertical GPS data throughout the area support the InSAR measured subsidence rates and extent. The subsidence rates for a few GPS stations northwest of Houston began to decrease in 2007, which may indicate that subsidence may be decreasing in these areas.
Marjanović, Marko; Kralj, Marijeta; Supek, Fran; Frkanec, Leo; Piantanida, Ivo; Smuc, Tomislav; Tusek-Bozić, Ljerka
2007-03-08
The present paper demonstrates the antiproliferative ability and structure-activity relationships (SAR) of 14 crown and aza-crown ether analogues on five tumor-cell types. The most active compounds were di-tert-butyldicyclohexano-18-crown-6 (3), which exhibited cytotoxicity in the submicromolar range, and di-tert-butyldibenzo-18-crown-6 (5) (IC50 values of approximately 2 microM). Also, 3 and 5 induced marked influence on the cell cycle phase distribution--strong G1 arrest, followed by the induction of apoptosis. A computational SAR modeling effort offers insight into possible mechanisms of crown ether biological activity, presumably involving penetration into cell membranes, and points out structural features of molecules important for this activity. The results reveal that crown ethers possess marked tumor-cell growth inhibitory activity, the extent of which depends on the characteristics of the hydrophilic macrocylic cavity and the surrounding hydrophobic ring. Our work supports the hypothesis that crown ether compounds inhibit tumor-cell growth by disrupting potassium ion homeostasis, which in turn leads to cell cycle perturbations and apoptosis.
Tang, Patrick; Louie, Marie; Richardson, Susan E.; Smieja, Marek; Simor, Andrew E.; Jamieson, Frances; Fearon, Margaret; Poutanen, Susan M.; Mazzulli, Tony; Tellier, Raymond; Mahony, James; Loeb, Mark; Petrich, Astrid; Chernesky, Max; McGeer, Allison; Low, Donald E.; Phillips, Elizabeth; Jones, Steven; Bastien, Nathalie; Li, Yan; Dick, Daryl; Grolla, Allen; Fernando, Lisa; Booth, Timothy F.; Henry, Bonnie; Rachlis, Anita R.; Matukas, Larissa M.; Rose, David B.; Lovinsky, Reena; Walmsley, Sharon; Gold, Wayne L.; Krajden, Sigmund
2004-01-01
Background An outbreak of severe acute respiratory syndrome (SARS) began in Canada in February 2003. The initial diagnosis of SARS was based on clinical and epidemiological criteria. During the outbreak, molecular and serologic tests for the SARS-associated coronavirus (SARS-CoV) became available. However, without a “gold standard,” it was impossible to determine the usefulness of these tests. We describe how these tests were used during the first phase of the SARS outbreak in Toronto and offer some recommendations that may be useful if SARS returns. Methods We examined the results of all diagnostic laboratory tests used in 117 patients admitted to hospitals in Toronto who met the Health Canada criteria for suspect or probable SARS. Focusing on tests for SARS-CoV, we attempted to determine the optimal specimen types and timing of specimen collection. Results Diagnostic test results for SARS-CoV were available for 110 of the 117 patients. SARS-CoV was detected by means of reverse-transcriptase polymerase chain reaction (RT-PCR) in at least one specimen in 59 (54.1%) of 109 patients. Serologic test results of convalescent samples were positive in 50 (96.2%) of 52 patients for whom paired serum samples were collected during the acute and convalescent phases of the illness. Of the 110 patients, 78 (70.9%) had specimens that tested positive by means of RT-PCR, serologic testing or both methods. The proportion of RT-PCR test results that were positive was similar between patients who met the criteria for suspect SARS (50.8%, 95% confidence interval [CI] 38.4%–63.2%) and those who met the criteria for probable SARS (58.0%, 95% CI 44.2%–70.7%). SARS-CoV was detected in nasopharyngeal swabs in 33 (32.4%) of 102 patients, in stool specimens in 19 (63.3%) of 30 patients, and in specimens from the lower respiratory tract in 10 (58.8%) of 17 patients. Interpretation These findings suggest that the rapid diagnostic tests in use at the time of the initial outbreak lack sufficient sensitivity to be used clinically to rule out SARS. As tests for SARS-CoV continue to be optimized, evaluation of the clinical presentation and elucidation of a contact history must remain the cornerstone of SARS diagnosis. In patients with SARS, specimens taken from the lower respiratory tract and stool samples test positive by means of RT-PCR more often than do samples taken from other areas. PMID:14707219
5. SWITCH TOWER AND JUNCTION OF S.A.R. #1 & S.A.R. ...
5. SWITCH TOWER AND JUNCTION OF S.A.R. #1 & S.A.R. #2 TRANSMISSION LINES, MARCH 7, 1916. SCE drawing no. 4932. - Santa Ana River Hydroelectric System, Transmission Lines, Redlands, San Bernardino County, CA
NASA Astrophysics Data System (ADS)
Gomez, Jaime; Pastena, Max; Bierens, Laurens
2013-08-01
MiniSAR is a Dutch program focused on the development of a commercial smallsat featuring a SAR instrument, led by SSBV as prime contractor. In this paper an Instrument Electronics (IEL) system concept to meet the MiniSAR demands is presented. This system has several specificities wrt similar initiatives in the European space industry, driven by our main requirement: keep it small.
Earth Studies Using L-band Synthetic Aperture Radar
NASA Technical Reports Server (NTRS)
Rosen, Paul A.
1999-01-01
L-band SAR has played an important role in studies of the Earth by revealing the nature of the larger-scale (decimeter) surface features. JERS-1, by supplying multi-seasonal coverage of the much of the earth, has demonstrated the importance of L-band SARs. Future L-band SARs such as ALOS and LightSAR will pave the way for science missions that use SAR instruments. As technology develops to enable lower cost SAR instruments, missions will evolve to each have a unique science focus. International coordination of multi-parameter constellations and campaigns will maximize science return.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Karr, T.J.
The SAR energy-aperture product limit is extended to multi-beam SARS, Spotlight and moving spotlight SARS. This fundamental limit bounds the tradeoff between energy and antenna size. The kinematic relations between design variables such as platform speed, pulse repetition frequency, beam width and area rate are analyzed in a unified framework applicable to a wide variety of SARs including strip maps, spotlights, vermer arrays and multi-beam SARS, both scanning and swept-beam. Then the energy-aperture product limit is derived from the signal-to noise requirement and the kinematic constraints. The derivation clarifies impact of multiple beams and spotlighting on SAR performance.
Anti-SARS coronavirus agents: a patent review (2008 - present).
Kumar, Vathan; Jung, Young-Sik; Liang, Po-Huang
2013-10-01
A novel coronavirus (CoV), unlike previous typical human coronaviruses (HCoVs), was identified as causative agent for severe acute respiratory syndrome (SARS). SARS first surfaced as a pandemic in late 2002 and originated in southern China. SARS-CoV rapidly spread to > 30 countries by 2003, infecting nearly 8,000 people and causing around 800 fatalities. After 10 years of silence, a 2012 report alarmed researchers about the emergence of a new strain of CoV causing SARS-like disease. To combat SARS, scientists applied for patents on various therapeutic agents, including small-molecule inhibitors targeting the essential proteases, helicase and other proteins of the virus, natural products, approved drugs, molecules binding to the virus, neutralizing antibodies, vaccines, anti-sense RNA, siRNA and ribozyme against SARS-CoV. In this article, the patents published from 2008 to the present for the new therapeutics that could potentially be used in the prophylaxis and treatment of SARS are reviewed. The therapeutic interventions or prophylaxis discussed in this review seems to offer promising solutions to tackle SARS. Rather than being complacent about the results, we should envisage how to transform them into drug candidates that may be useful in combating SARS and related viral infections in the future.
NASA Astrophysics Data System (ADS)
Yazıcı, Birsen; Son, Il-Young; Cagri Yanik, H.
2018-05-01
This paper introduces a new and novel radar interferometry based on Doppler synthetic aperture radar (Doppler-SAR) paradigm. Conventional SAR interferometry relies on wideband transmitted waveforms to obtain high range resolution. Topography of a surface is directly related to the range difference between two antennas configured at different positions. Doppler-SAR is a novel imaging modality that uses ultra-narrowband continuous waves (UNCW). It takes advantage of high resolution Doppler information provided by UNCWs to form high resolution SAR images. We introduce the theory of Doppler-SAR interferometry. We derive an interferometric phase model and develop the equations of height mapping. Unlike conventional SAR interferometry, we show that the topography of a scene is related to the difference in Doppler frequency between two antennas configured at different velocities. While the conventional SAR interferometry uses range, Doppler and Doppler due to interferometric phase in height mapping; Doppler-SAR interferometry uses Doppler, Doppler-rate and Doppler-rate due to interferometric phase in height mapping. We demonstrate our theory in numerical simulations. Doppler-SAR interferometry offers the advantages of long-range, robust, environmentally friendly operations; low-power, low-cost, lightweight systems suitable for low-payload platforms, such as micro-satellites; and passive applications using sources of opportunity transmitting UNCW.
Interferometric synthetic aperture radar: Building tomorrow's tools today
Lu, Zhong
2006-01-01
A synthetic aperture radar (SAR) system transmits electromagnetic (EM) waves at a wavelength that can range from a few millimeters to tens of centimeters. The radar wave propagates through the atmosphere and interacts with the Earth’s surface. Part of the energy is reflected back to the SAR system and recorded. Using a sophisticated image processing technique, called SAR processing (Curlander and McDonough, 1991), both the intensity and phase of the reflected (or backscattered) signal of each ground resolution element (a few meters to tens of meters) can be calculated in the form of a complex-valued SAR image representing the reflectivity of the ground surface. The amplitude or intensity of the SAR image is determined primarily by terrain slope, surface roughness, and dielectric constants, whereas the phase of the SAR image is determined primarily by the distance between the satellite antenna and the ground targets, slowing of the signal by the atmosphere, and the interaction of EM waves with ground surface. Interferometric SAR (InSAR) imaging, a recently developed remote sensing technique, utilizes the interaction of EM waves, referred to as interference, to measure precise distances. Very simply, InSAR involves the use of two or more SAR images of the same area to extract landscape topography and its deformation patterns.
NASA Astrophysics Data System (ADS)
Chen, Jingyi; Knight, Rosemary; Zebker, Howard A.; Schreüder, Willem A.
2016-05-01
Interferometric Synthetic Aperture Radar (InSAR), a remote sensing technique for measuring centimeter-level surface deformation, is used to estimate hydraulic head in the confined aquifer of the San Luis Valley (SLV), Colorado. Reconstructing head measurements from InSAR in agricultural regions can be difficult, as InSAR phase data are often decorrelated due to vegetation growth. Analysis of 17 L-band ALOS PALSAR scenes, acquired between January 2007 and March 2011, demonstrates that comprehensive InSAR deformation measurements can be recovered over the vegetated groundwater basin with an improved processing strategy. Local skeletal storage coefficients and time delays between the head change and deformation are estimated through a joint InSAR-well data analysis. InSAR subsidence estimates are transformed to head changes with finer temporal and spatial resolution than is possible using existing well records alone. Both InSAR and well data suggest that little long-term water-storage loss occurred in the SLV over the study period and that inelastic compaction was negligible. The seasonal head variations derived from InSAR are consistent with the existing well data at most locations where confined aquifer pumping activity dominates. Our results demonstrate the advantages of InSAR measurements for basin-wide characterization of aquifer storage properties and groundwater levels over agricultural regions.
A multi-channel instrumentation system for biosignal recording.
Yu, Hong; Li, Pengfei; Xiao, Zhiming; Peng, Chung-Ching; Bashirullah, Rizwan
2008-01-01
This paper reports a highly integrated battery operated multi-channel instrumentation system intended for physiological signal recording. The mixed signal IC has been fabricated in standard 0.5microm 5V 3M-2P CMOS process and features 32 instrumentation amplifiers, four 8b SAR ADCs, a wireless power interface with Li-ion battery charger, low power bidirectional telemetry and FSM controller with power gating control for improved energy efficiency. The chip measures 3.2mm by 4.8mm and dissipates approximately 2.1mW when fully operational.
Space Radar Image of Altona, Manitoba, Canada
NASA Technical Reports Server (NTRS)
1994-01-01
This is an X-band seasonal image of the Altona test site in Manitoba, Canada, about 80 kilometers (50 miles) south of Winnipeg. The image is centered at approximately 49 degrees north latitude and 97.5 degrees west longitude. This image was acquired by the Spaceborne Imaging Radar-C and X-band Synthetic Aperture Radar (SIR-C/X-SAR) aboard the space shuttle Endeavour on April 11, 1994, during the first flight of the radar system, and on October 2, 1994, during the second flight of SIR-C/X-SAR. The image channels have the following color assignments: red represents data acquired on April 11, 1994; green represents data acquired on October 2, 1994; blue represents the ratio of the two data sets. The test site is located in the Red River Basin and is characterized by rich farmland where a variety of crops are grown, including wheat, barley, canola, corn, sunflowers and sugar beets. This SIR-C/X-SAR research site is applying radar remote sensing to study the characteristics of vegetation and soil moisture. The seasonal comparison between the April and October 1994 data show the dramatic differences between surface conditions on the two dates. At the time of the April acquisition, almost all agricultural fields were bare and soil moisture levels were high. In October, however, soils were drier and while most crops had been harvested, some standing vegetation was still present. The areas which are cyan in color are dark in April and bright in October. These represent fields of standing biomass (amount of vegetation in a specified area) and the differences in brightness within these cyan fields represent differences in vegetation type. The very bright fields in October represent standing broadleaf crops such as corn, which had not yet been harvested. Other standing vegetation which has less biomass, such as hay and grain fields, are less bright. The magenta indicates bare soil surfaces which were wetter (brighter) in April than in October. The variations in brightness of the magenta indicate differences in the degree of soil moisture change and differences in surface roughness. This seasonal composite demonstrates the sensitivity of radar to changes in agricultural surface conditions such as soil moisture, tillage, cropping and harvesting. Spaceborne Imaging Radar-C and X-band Synthetic Aperture Radar (SIR-C/X-SAR) is part of NASA's Mission to Planet Earth. The radars illuminate Earth with microwaves, allowing detailed observations at any time, regardless of weather or sunlight conditions. SIR-C/X-SAR uses three microwave wavelengths: L-band (24 cm), C-band (6 cm) and X-band (3 cm). The multi-frequency data will be used by the international scientific community to better understand the global environment and how it is changing. The SIR-C/X-SAR data, complemented by aircraft and ground studies, will give scientists clearer insights into those environmental changes which are caused by nature and those changes which are induced by human activity. SIR-C was developed by NASA's Jet Propulsion Laboratory. X-SAR was developed by the Dornier and Alenia Spazio companies for the German space agency, Deutsche Agentur fuer Raumfahrtangelegenheiten (DARA), and the Italian space agency, Agenzia Spaziale Italiana (ASI), with the Deutsche Forschungsanstalt fuer Luft und Raumfahrt e.V.(DLR), the major partner in science, operations and data processing of X-SAR.
Space Radar Image of Manaus region of Brazil
NASA Technical Reports Server (NTRS)
1994-01-01
These L-band images of the Manaus region of Brazil were acquired by the Spaceborne Imaging Radar-C and X-band Synthetic Aperture Radar (SIR-C/X-SAR) aboard the space shuttle Endeavour. The left image was acquired on April 12, 1994, and the middle image was acquired on October 3, 1994. The area shown is approximately 8 kilometers by 40 kilometers (5 miles by 25 miles). The two large rivers in this image, the Rio Negro (top) and the Rio Solimoes (bottom), combine at Manaus (west of the image) to form the Amazon River. The image is centered at about 3 degrees south latitude and 61 degrees west longitude. North is toward the top left of the images. The differences in brightness between the images reflect changes in the scattering of the radar channel. In this case, the changes are indicative of flooding. A flooded forest has a higher backscatter at L-band (horizontally transmitted and received) than an unflooded river. The extent of the flooding is much greater in the April image than in the October image, and corresponds to the annual, 10-meter (33-foot) rise and fall of the Amazon River. A third image at right shows the change in the April and October images and was created by determining which areas had significant decreases in the intensity of radar returns. These areas, which appear blue on the third image at right, show the dramatic decrease in the extent of flooded forest, as the level of the Amazon River falls. The flooded forest is a vital habitat for fish and floating meadows are an important source of atmospheric methane. This demonstrates the capability of SIR-C/X-SAR to study important environmental changes that are impossible to see with optical sensors over regions such as the Amazon, where frequent cloud cover and dense forest canopies obscure monitoring of floods. Field studies by boat, on foot and in low-flying aircraft by the University of California at Santa Barbara, in collaboration with Brazil's Instituto Nacional de Pesguisas Estaciais, during the first and second flights of the SIR-C/X-SAR system have validated the interpretation of the radar images. Spaceborne Imaging Radar-C and X-band Synthetic Aperture Radar (SIR-C/X-SAR) is part of NASA's Mission to Planet Earth. The radars illuminate Earth with microwaves, allowing detailed observations at any time, regardless of weather or sunlight conditions. SIR-C/X-SAR uses three microwave wavelengths: L-band (24 cm), C-band (6 cm) and X-band (3 cm). The multi-frequency data will be used by the international scientific community to better understand the global environment and how it is changing. The SIR-C/X-SAR data, complemented by aircraft and ground studies, will give scientists clearer insights into those environmental changes which are caused by nature and those changes which are induced by human activity. SIR-C was developed by NASA's Jet Propulsion Laboratory. X-SAR was developed by the Dornier and Alenia Spazio companies for the German space agency, Deutsche Agentur fuer Raumfahrtangelegenheiten (DARA), and the Italian space agency, Agenzia Spaziale Italiana (ASI), with the Deutsche Forschungsanstalt fuer Luft und Raumfahrt e.V.(DLR), the major partner in science, operations and data processing of X-SAR.
Bernsdorff, Friederike; Döring, Anne-Christin; Gruner, Katrin; Schuck, Stefan; Bräutigam, Andrea; Zeier, Jürgen
2016-01-01
We investigated the relationships of the two immune-regulatory plant metabolites, salicylic acid (SA) and pipecolic acid (Pip), in the establishment of plant systemic acquired resistance (SAR), SAR-associated defense priming, and basal immunity. Using SA-deficient sid2, Pip-deficient ald1, and sid2 ald1 plants deficient in both SA and Pip, we show that SA and Pip act both independently from each other and synergistically in Arabidopsis thaliana basal immunity to Pseudomonas syringae. Transcriptome analyses reveal that SAR establishment in Arabidopsis is characterized by a strong transcriptional response systemically induced in the foliage that prepares plants for future pathogen attack by preactivating multiple stages of defense signaling and that SA accumulation upon SAR activation leads to the downregulation of photosynthesis and attenuated jasmonate responses systemically within the plant. Whereas systemic Pip elevations are indispensable for SAR and necessary for virtually the whole transcriptional SAR response, a moderate but significant SA-independent component of SAR activation and SAR gene expression is revealed. During SAR, Pip orchestrates SA-dependent and SA-independent priming of pathogen responses in a FLAVIN-DEPENDENT-MONOOXYGENASE1 (FMO1)-dependent manner. We conclude that a Pip/FMO1 signaling module acts as an indispensable switch for the activation of SAR and associated defense priming events and that SA amplifies Pip-triggered responses to different degrees in the distal tissue of SAR-activated plants. PMID:26672068
Local region power spectrum-based unfocused ship detection method in synthetic aperture radar images
NASA Astrophysics Data System (ADS)
Wei, Xiangfei; Wang, Xiaoqing; Chong, Jinsong
2018-01-01
Ships on synthetic aperture radar (SAR) images will be severely defocused and their energy will disperse into numerous resolution cells under long SAR integration time. Therefore, the image intensity of ships is weak and sometimes even overwhelmed by sea clutter on SAR image. Consequently, it is hard to detect the ships from SAR intensity images. A ship detection method based on local region power spectrum of SAR complex image is proposed. Although the energies of the ships are dispersed on SAR intensity images, their spectral energies are rather concentrated or will cause the power spectra of local areas of SAR images to deviate from that of sea surface background. Therefore, the key idea of the proposed method is to detect ships via the power spectra distortion of local areas of SAR images. The local region power spectrum of a moving target on SAR image is analyzed and the way to obtain the detection threshold through the probability density function (pdf) of the power spectrum is illustrated. Numerical P- and L-band airborne SAR ocean data are utilized and the detection results are also illustrated. Results show that the proposed method can well detect the unfocused ships, with a detection rate of 93.6% and a false-alarm rate of 8.6%. Moreover, by comparing with some other algorithms, it indicates that the proposed method performs better under long SAR integration time. Finally, the applicability of the proposed method and the way of parameters selection are also discussed.
Bernsdorff, Friederike; Döring, Anne-Christin; Gruner, Katrin; Schuck, Stefan; Bräutigam, Andrea; Zeier, Jürgen
2016-01-01
We investigated the relationships of the two immune-regulatory plant metabolites, salicylic acid (SA) and pipecolic acid (Pip), in the establishment of plant systemic acquired resistance (SAR), SAR-associated defense priming, and basal immunity. Using SA-deficient sid2, Pip-deficient ald1, and sid2 ald1 plants deficient in both SA and Pip, we show that SA and Pip act both independently from each other and synergistically in Arabidopsis thaliana basal immunity to Pseudomonas syringae. Transcriptome analyses reveal that SAR establishment in Arabidopsis is characterized by a strong transcriptional response systemically induced in the foliage that prepares plants for future pathogen attack by preactivating multiple stages of defense signaling and that SA accumulation upon SAR activation leads to the downregulation of photosynthesis and attenuated jasmonate responses systemically within the plant. Whereas systemic Pip elevations are indispensable for SAR and necessary for virtually the whole transcriptional SAR response, a moderate but significant SA-independent component of SAR activation and SAR gene expression is revealed. During SAR, Pip orchestrates SA-dependent and SA-independent priming of pathogen responses in a FLAVIN-DEPENDENT-MONOOXYGENASE1 (FMO1)-dependent manner. We conclude that a Pip/FMO1 signaling module acts as an indispensable switch for the activation of SAR and associated defense priming events and that SA amplifies Pip-triggered responses to different degrees in the distal tissue of SAR-activated plants. © 2016 American Society of Plant Biologists. All rights reserved.
Integration of SAR and AIS for ship detection and identification
NASA Astrophysics Data System (ADS)
Yang, Chan-Su; Kim, Tae-Ho
2012-06-01
This abstract describes the preliminary design concept for an integration system of SAR and AIS data. SAR sensors are used to acquire image data over large coverage area either through the space borne or airborne platforms in UTC. AIS reports should also obtained on the same date as of the SAR acquisition for the purpose to perform integration test. Once both data reports are obtained, one need to match the timings of AIS data acquisition over the SAR image acquisition time with consideration of local time & boundary to extract the closest time signal from AIS report in order to know the AIS based ship positions, but still one cannot be able to distinguish which ships have the AIS transponder after projection of AIS based position onto the SAR image acquisition boundary. As far as integration is concerned, the ship dead-reckoning concept is most important forecasted position which provides the AIS based ship position at the time of SAR image acquisition and also provides the hints for azimuth shift which occurred in SAR image for the case of moving ships which moves in the direction perpendicular to the direction of flight path. Unknown ship's DR estimation is to be carried out based on the initial positions, speed and course over ground, which has already been shorted out from AIS reports, during the step of time matching. This DR based ship's position will be the candidate element for searching the SAR based ship targets for the purpose of identification & matching within the certain boundary around DR. The searching method is performed by means of estimation of minimum distance from ship's DR to SAR based ship position, and once it determines, so the candidate element will look for matching like ship size match of DR based ship's dimension wrt SAR based ship's edge, there may be some error during the matching with SAR based ship edges with actual ship's hull design as per the longitudinal and transverse axis size information obtained from the AIS reports due to blurring effect in SAR based ship signatures, once the conditions are satisfied, candidate element will move & shift over the SAR based ship signature target with the minimum displacement and it is known to be the azimuth shift compensation and this overall methodology are known to be integration of AIS report data over the SAR image acquisition boundary with assessment of time matching. The expected result may provide the good accuracy of the SAR and AIS contact position along with dimension and classification of ships over SAR image. There may be possibilities of matching speed and course from candidate element with SAR based ship signature, but still the challenges are presents in front of us that to estimation of speed and course by means of SAR data, if it may be possible so the expected final result may be more accurate as due to extra matching effects and the results may be used for the near real time performance for ship identification with help of integrated system design based on SAR and AIS data reports.
NASA Astrophysics Data System (ADS)
Montazeri, Sina; Gisinger, Christoph; Eineder, Michael; Zhu, Xiao xiang
2018-05-01
Geodetic stereo Synthetic Aperture Radar (SAR) is capable of absolute three-dimensional localization of natural Persistent Scatterer (PS)s which allows for Ground Control Point (GCP) generation using only SAR data. The prerequisite for the method to achieve high precision results is the correct detection of common scatterers in SAR images acquired from different viewing geometries. In this contribution, we describe three strategies for automatic detection of identical targets in SAR images of urban areas taken from different orbit tracks. Moreover, a complete work-flow for automatic generation of large number of GCPs using SAR data is presented and its applicability is shown by exploiting TerraSAR-X (TS-X) high resolution spotlight images over the city of Oulu, Finland and a test site in Berlin, Germany.
Low-SAR metamaterial-inspired printed monopole antenna
NASA Astrophysics Data System (ADS)
Hossain, M. I.; Faruque, M. R. I.; Islam, M. T.; Ali, M. T.
2017-01-01
In this paper, a low-SAR metamaterial-embedded planar monopole antenna is introduced for a wireless communication system. A printed monopole antenna is designed for modern mobile, which operates in GSM, UMTS, LTE, WLAN, and Bluetooth frequency bands. A metamaterial structure is designed to use in the mobile handset with a multi-band printed monopole antenna. The finite integration technique of the CST microwave studio is used in this study. The measurement of antenna performances is taken in an anechoic chamber, and the SAR values are measured using COMOSAR system. The results indicate that metamaterial structure leads to reduce SAR without affecting antenna performance significantly. According to the measured results, the metamaterial attachment leads to reduce 87.7% peak SAR, 68.2% 1-g SAR, and 46.78% 10-g SAR compared to antenna without metamaterial.
Satellite on-board real-time SAR processor prototype
NASA Astrophysics Data System (ADS)
Bergeron, Alain; Doucet, Michel; Harnisch, Bernd; Suess, Martin; Marchese, Linda; Bourqui, Pascal; Desnoyers, Nicholas; Legros, Mathieu; Guillot, Ludovic; Mercier, Luc; Châteauneuf, François
2017-11-01
A Compact Real-Time Optronic SAR Processor has been successfully developed and tested up to a Technology Readiness Level of 4 (TRL4), the breadboard validation in a laboratory environment. SAR, or Synthetic Aperture Radar, is an active system allowing day and night imaging independent of the cloud coverage of the planet. The SAR raw data is a set of complex data for range and azimuth, which cannot be compressed. Specifically, for planetary missions and unmanned aerial vehicle (UAV) systems with limited communication data rates this is a clear disadvantage. SAR images are typically processed electronically applying dedicated Fourier transformations. This, however, can also be performed optically in real-time. Originally the first SAR images were optically processed. The optical Fourier processor architecture provides inherent parallel computing capabilities allowing real-time SAR data processing and thus the ability for compression and strongly reduced communication bandwidth requirements for the satellite. SAR signal return data are in general complex data. Both amplitude and phase must be combined optically in the SAR processor for each range and azimuth pixel. Amplitude and phase are generated by dedicated spatial light modulators and superimposed by an optical relay set-up. The spatial light modulators display the full complex raw data information over a two-dimensional format, one for the azimuth and one for the range. Since the entire signal history is displayed at once, the processor operates in parallel yielding real-time performances, i.e. without resulting bottleneck. Processing of both azimuth and range information is performed in a single pass. This paper focuses on the onboard capabilities of the compact optical SAR processor prototype that allows in-orbit processing of SAR images. Examples of processed ENVISAT ASAR images are presented. Various SAR processor parameters such as processing capabilities, image quality (point target analysis), weight and size are reviewed.
The effect of severe acute respiratory syndrome (SARS) on emergency airway management.
Wong, Evelyn; Ho, Khoy Kheng
2006-07-01
From early March 2003 to late May 2003, severe acute respiratory syndrome (SARS) was detected in Singapore. The increase in workload and new infection control procedures were thought to affect resuscitation and airway management. Our aim was to study the effects of wearing of personal protective equipment (PPE) and powered air-purifying respirator (PAPR) and the restriction in the number of resuscitation personnel on airway management during the SARS crisis. Data was collected prospectively through an ongoing emergency airway registry. The data was divided into three periods: (1) before PPE was instituted from 1 November 2002 to 31 March 2003; (2) during SARS (when PPE use was mandatory) from 1 April to 31 July 2003; (3) post-SARs (when PPE use was non-mandatory but encouraged) from 1 August to 31 March 2004. There was no change in patient demographics during the three periods. There were significant increases in the proportion of resuscitation cases and airway interventions during the SARS period compared to the pre-SARS period. The resident medical officer intubation rate decreased from 45.1% pre-SARS to 35.2% during SARS and 17.7% post-SARS. The complication rates were 10.5%, 9.9% and 9.4% in periods 1-3, respectively. Restriction in the number of healthcare staff attending to each patient may have influenced the department's decision to allow only the most confident or experienced personnel to manage the airway. The exposure of junior medical officers in emergency airway management during SARS and the immediate post-SARS period was decreased. This trend should be monitored further and intervention may be necessary should it continue to decline.
The integration of Human Factors (HF) in the SAR process training course text
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ryan, T.G.
1995-03-01
This text provides the technical basis for a two-day course on human factors (HF), as applied to the Safety Analysis Report (SAR) process. The overall objective of this text and course is to: provide the participant with a working knowledge of human factors-related requirements, suggestions for doing a human safety analysis applying a graded approach, and an ability to demonstrate using the results of the human safety analysis, that human factors elements as defined by DOE (human factors engineering, procedures, training, oversight, staffing, qualifications), can support wherever necessary, nuclear safety commitments in the SAR. More specifically, the objectives of themore » text and course are: (1) To provide the SAR preparer with general guidelines for doing HE within the context of a graded approach for the SAR; (2) To sensitize DOE facility managers and staff, safety analysts and SAR preparers, independent reviewers, and DOE reviewers and regulators, to DOE Order 5480.23 requirements for HE in the SAR; (3) To provide managers, analysts, reviewers and regulators with a working knowledge of HE concepts and techniques within the context of a graded approach for the SAR, and (4) To provide SAR managers and DOE reviewers and regulators with general guidelines for monitoring and coordinating the work of preparers of HE inputs throughout the SAR process, and for making decisions regarding the safety relevance of HE inputs to the SAR. As a ready reference for implementing the human factors requirements of DOE Order 5480.22 and DOE Standard 3009-94, this course text and accompanying two-day course are intended for all persons who are involved in the SAR.« less
Concatenated shift registers generating maximally spaced phase shifts of PN-sequences
NASA Technical Reports Server (NTRS)
Hurd, W. J.; Welch, L. R.
1977-01-01
A large class of linearly concatenated shift registers is shown to generate approximately maximally spaced phase shifts of pn-sequences, for use in pseudorandom number generation. A constructive method is presented for finding members of this class, for almost all degrees for which primitive trinomials exist. The sequences which result are not normally characterized by trinomial recursions, which is desirable since trinomial sequences can have some undesirable randomness properties.
2004-08-01
of Female Rodent Carcinogens PRINCIPAL INVESTIGATOR: Albert R. Cunningham, Ph.D. CONTRACTING ORGANIZATION : Louisiana State University, Baton Rouge... non -carcinogen) and molecular fragments as SAR descriptors. Therefore, this seemed a reasonable substitute SAR approach for MCASE. However, upon... target site summary (15) we developed a SAR learning set of 100 compounds shown to induce breast cancer in rat. The cat- SAR program develops SAR
23. OVERVIEW OF SAR3 AREA, SHOWING CORNER OF SAR3 WITH ...
23. OVERVIEW OF SAR-3 AREA, SHOWING CORNER OF SAR-3 WITH TAILRACE, ADMINISTRATIVE OFFICE, TOILET SHED, AND RETAINING WALLS AT FORMER EMPLOYEE HOUSING SITE. VIEW TO SOUTHEAST. PANORAMA 1/2. - Santa Ana River Hydroelectric System, Redlands, San Bernardino County, CA
NASA Technical Reports Server (NTRS)
Evans, D. L. (Editor); Apel, J.; Arvidson, R.; Bindschadler, R.; Carsey, F.; Dozier, J.; Jezek, K.; Kasischke, E.; Li, F.; Melack, J.
1995-01-01
This report provides a context in which questions put forth by NASA's Office of Mission to Planet Earth (OMPTE) regarding the next steps in spaceborne synthetic aperture radar (SAR) science and technology can be addressed. It summarizes the state-of-the-art in theory, experimental design, technology, data analysis, and utilization of SAR data for studies of the Earth, and describes potential new applications. The report is divided into five science chapters and a technology assessment. The chapters summarize the value of existing SAR data and currently planned SAR systems, and identify gaps in observational capabilities needing to be filled to address the scientific questions. Cases where SAR provides complementary data to other (non-SAR) measurement techniques are also described. The chapter on technology assessment outlines SAR technology development which is critical not only to NASA's providing societally relevant geophysical parameters but to maintaining competitiveness in SAR technology, and promoting economic development.
What InSAR time-series methods are best suited for the Ecuadorian volcanoes
NASA Astrophysics Data System (ADS)
Mirzaee, S.; Amelung, F.
2017-12-01
Ground displacement measurements from stacks of SAR images obtained using interferometric time-series approaches play an increasingly important role for volcanic hazard assessment. The inflation of the ground surface can indicate that magma ascends to shallower levels and that a volcano gets ready for an eruption. Commonly used InSAR time-series approaches include Small Baseline (SB), Persistent Scatter InSAR (PSI) and SqueeSAR methods but it remains unclear which approach is best suited for volcanic environments. On this poster we present InSAR deformation measurements for the active volcanoes of Ecuador (Cotopaxi, Tungurahua and Pichincha) using a variety of INSAR time-series methods. We discuss the pros and cons of each method given the available data stacks (TerraSAR-X, Cosmo-Skymed and Sentinel-1) in an effort to design a comprehensive observation strategy for the Ecuadorian volcanoes. SAR data are provided in the framework of the Group on Earth Observation's Ecuadorian Volcano Geohazard Supersite.
T-cell immunity of SARS-CoV: Implications for vaccine development against MERS-CoV.
Liu, William J; Zhao, Min; Liu, Kefang; Xu, Kun; Wong, Gary; Tan, Wenjie; Gao, George F
2017-01-01
Over 12 years have elapsed since severe acute respiratory syndrome (SARS) triggered the first global alert for coronavirus infections. Virus transmission in humans was quickly halted by public health measures and human infections of SARS coronavirus (SARS-CoV) have not been observed since. However, other coronaviruses still pose a continuous threat to human health, as exemplified by the recent emergence of Middle East respiratory syndrome (MERS) in humans. The work on SARS-CoV widens our knowledge on the epidemiology, pathophysiology and immunology of coronaviruses and may shed light on MERS coronavirus (MERS-CoV). It has been confirmed that T-cell immunity plays an important role in recovery from SARS-CoV infection. Herein, we summarize T-cell immunological studies of SARS-CoV and discuss the potential cross-reactivity of the SARS-CoV-specific immunity against MERS-CoV, which may provide useful recommendations for the development of broad-spectrum vaccines against coronavirus infections. Copyright © 2016 Elsevier B.V. All rights reserved.
Altered Lipid Metabolism in Recovered SARS Patients Twelve Years after Infection.
Wu, Qi; Zhou, Lina; Sun, Xin; Yan, Zhongfang; Hu, Chunxiu; Wu, Junping; Xu, Long; Li, Xue; Liu, Huiling; Yin, Peiyuan; Li, Kuan; Zhao, Jieyu; Li, Yanli; Wang, Xiaolin; Li, Yu; Zhang, Qiuyang; Xu, Guowang; Chen, Huaiyong
2017-08-22
Severe acute respiratory syndrome-coronavirus (SARS-CoV) and SARS-like coronavirus are a potential threat to global health. However, reviews of the long-term effects of clinical treatments in SARS patients are lacking. Here a total of 25 recovered SARS patients were recruited 12 years after infection. Clinical questionnaire responses and examination findings indicated that the patients had experienced various diseases, including lung susceptibility to infections, tumors, cardiovascular disorders, and abnormal glucose metabolism. As compared to healthy controls, metabolomic analyses identified significant differences in the serum metabolomes of SARS survivors. The most significant metabolic disruptions were the comprehensive increase of phosphatidylinositol and lysophospha tidylinositol levels in recovered SARS patients, which coincided with the effect of methylprednisolone administration investigated further in the steroid treated non-SARS patients with severe pneumonia. These results suggested that high-dose pulses of methylprednisolone might cause long-term systemic damage associated with serum metabolic alterations. The present study provided information for an improved understanding of coronavirus-associated pathologies, which might permit further optimization of clinical treatments.
Roh, Changhyun
2012-01-01
Hundreds of million people worldwide have been infected with severe acute respiratory syndrome (SARS), and the rate of global death from SARS has remarkably increased. Hence, the development of efficient drug treatments for the biological effects of SARS is highly needed. We have previously shown that quantum dots (QDs)-conjugated RNA oligonucleotide is sensitive to the specific recognition of the SARS-associated coronavirus (SARS-CoV) nucleocapsid (N) protein. In this study, we found that a designed biochip could analyze inhibitors of the SARS-CoV N protein using nanoparticle-based RNA oligonucleotide. Among the polyphenolic compounds examined, (-)-catechin gallate and (-)-gallocatechin gallate demonstrated a remarkable inhibition activity on SARS-CoV N protein. (-)-catechin gallate and (-)-gallocatechin gallate attenuated the binding affinity in a concentrated manner as evidenced by QDs-conjugated RNA oligonucleotide on a designed biochip. At a concentration of 0.05 μg mL(-1), (-)-catechin gallate and (-)-gallocatechin gallate showed more than 40% inhibition activity on a nanoparticle-based RNA oligonucleotide biochip system.
The Alaska SAR processor - Operations and control
NASA Technical Reports Server (NTRS)
Carande, Richard E.
1989-01-01
The Alaska SAR (synthetic-aperture radar) Facility (ASF) will be capable of receiving, processing, archiving, and producing a variety of SAR image products from three satellite-borne SARs: E-ERS-1 (ESA), J-ERS-1 (NASDA) and Radarsat (Canada). Crucial to the success of the ASF is the Alaska SAR processor (ASP), which will be capable of processing over 200 100-km x 100-km (Seasat-like) frames per day from the raw SAR data, at a ground resolution of about 30 m x 30 m. The processed imagery is of high geometric and radiometric accuracy, and is geolocated to within 500 m. Special-purpose hardware has been designed to execute a SAR processing algorithm to achieve this performance. This hardware is currently undergoing acceptance testing for delivery to the University of Alaska. Particular attention has been devoted to making the operations semi-automated and to providing a friendly operator interface via a computer workstation. The operations and control of the Alaska SAR processor are described.
Beyond SARS: ethnic community organization's role in public health -- a Toronto experience.
Weizhen Dong
2008-12-01
The SARS outbreak in Toronto was a public health crisis. It was particularly frightening to the Chinese-Canadians, because of the origin of the deadly disease. The Chinese-Canadian community organizations launched various activities to help the Chinese-Canadians as well as other Asian-Canadian communities to fight against SARS and its social side-effects. From launching the SARS Supporting Line, distributing health promotional material, disseminating SARS related information, paying tribute to frontline health workers, and promoting local business, to fundraising for SARS related research; they played an active role in easing the public's anxiety, especially for the Chinese-Canadians in the great Toronto area. The culturally diverse population brought problems as well as solutions. Ethnic groups have expertise in almost all areas, including people with leadership skills. The Toronto Chinese community's experience in combating SARS is a good example. The Chinese-Canadian community organizations' activities during the SARS outbreak demonstrate that ethnic minority organizations can play an important role in public health, especially in a public health crisis, and beyond.
NASA Astrophysics Data System (ADS)
Lavender, Samantha; Haria, Kajal; Cooksley, Geraint; Farman, Alex; Beaton, Thomas
2016-08-01
The aim was to understand a future market for NovaSAR-S, with a particular focus on flood mapping, through developing a simple Synthetic Aperture Radar (SAR) simulator that can be used in advance of NovaSAR-S data becoming available.The return signal was determined from a combination of a terrain or elevation model, Envisat S-Band Radar Altimeter (RA)-2, Landsat and CORINE land cover information; allowing for a simulation of a SAR image that's influenced by both the geometry and surface type. The test sites correspond to data from the 2014 AirSAR campaign, and validation is performed by using AirSAR together with Envisat Advanced (ASAR) and Advanced Land Observing Satellite "Daichi" (ALOS) Phased Array type L-Band Synthetic Aperture Radar (PALSAR) data.It's envisaged that the resulting simulated data, and the simulator, will not only aid early understanding of NovaSAR-S, but will also aid the development of flood mapping applications.
Evaluation of Airborne l- Band Multi-Baseline Pol-Insar for dem Extraction Beneath Forest Canopy
NASA Astrophysics Data System (ADS)
Li, W. M.; Chen, E. X.; Li, Z. Y.; Jiang, C.; Jia, Y.
2018-04-01
DEM beneath forest canopy is difficult to extract with optical stereo pairs, InSAR and Pol-InSAR techniques. Tomographic SAR (TomoSAR) based on different penetration and view angles could reflect vertical structure and ground structure. This paper aims at evaluating the possibility of TomoSAR for underlying DEM extraction. Airborne L-band repeat-pass Pol-InSAR collected in BioSAR 2008 campaign was applied to reconstruct the 3D structure of forest. And sum of kronecker product and algebraic synthesis algorithm were used to extract ground structure, and phase linking algorithm was applied to estimate ground phase. Then Goldstein cut-branch approach was used to unwrap the phases and then estimated underlying DEM. The average difference between the extracted underlying DEM and Lidar DEM is about 3.39 m in our test site. And the result indicates that it is possible for underlying DEM estimation with airborne L-band repeat-pass TomoSAR technique.
NASA Astrophysics Data System (ADS)
Liu, Chunhui; Zhang, Duona; Zhao, Xintao
2018-03-01
Saliency detection in synthetic aperture radar (SAR) images is a difficult problem. This paper proposed a multitask saliency detection (MSD) model for the saliency detection task of SAR images. We extract four features of the SAR image, which include the intensity, orientation, uniqueness, and global contrast, as the input of the MSD model. The saliency map is generated by the multitask sparsity pursuit, which integrates the multiple features collaboratively. Detection of different scale features is also taken into consideration. Subjective and objective evaluation of the MSD model verifies its effectiveness. Based on the saliency maps obtained by the MSD model, we apply the saliency map of the SAR image to the SAR and color optical image fusion. The experimental results of real data show that the saliency map obtained by the MSD model helps to improve the fusion effect, and the salient areas in the SAR image can be highlighted in the fusion results.
Study of Ground Subsidence in North West Houston using GPS, LiDAR and InSAR techniques
NASA Astrophysics Data System (ADS)
Karacay, A.; Khan, S. D.
2012-12-01
Land subsidence can be caused by natural or human activities, such as carbonate dissolution, extraction of material from mines, soil compaction and fluid withdrawal. This phenomenon affects many cities around the world, such as Nagoya-Japan, Venice-Italy, San Joaquin Valley and Long Beach in California. Recent work by Engelkemeir et al, (2010), suggested that subsidence occurred as high as 5.6 cm/year in northwest Houston. The processes that may contribute to land subsidence in the Houston-Galveston area includes faulting, soil compaction, salt tectonic, water pumping and hydrocarbon extraction. This study aims to assess the possible role of water pumping on subsidence. Northwest Houston has two aquifer systems, the Evangeline and Chicot aquifers that dip in the southeast direction. The effect of water pumping on subsidence from these two aquifers was monitored using InSAR, GPS and LiDAR data. The data from eleven GPS stations were processed using Online Positioning User Service (OPUS) of National Geodetic Survey (NGS). Three of these GPS stations are Continuously Operating Reference Stations (CORS) and eight are Port-A-Measure (PAM) sites. All the GPS data were obtained from Harris-Galveston Subsidence District (HGSD). CORS sites were used as reference stations for processing GPS data from the PAM stations. GPS data show that subsidence rate in northwest Houston decreased to approximately 2 cm/year. In addition, the surface deformation is also estimated using Light Detection and Ranging (LiDAR) technique. For this purpose, raw LiDAR (LAS-Long ASCII Standart) files of 2001 and 2008 were processed. The subsidence rate near the Hockley Fault was calculated by applying zonal statistics method on LiDAR data which shows about 10 cm of subsidence in nine years. This result is supported by processed GPS data from PAM site 48 that show subsidence rate of 1.3 cm/yr. For the InSAR (Interferometric Synthetic Aperture Radar) technique, an image pair of PALSAR (The Phased Array type L-band Synthetic Aperture Radar) for 2008 was processed using Sarscape ENVI. The result demonstrates both uplift (approximately 5 mm near the Tomball salt dome) and subsidence (approximately 5.3 mm on the west part of Tomball region). In order to improve results, other image pairs from PALSAR, ERS1/2 and ENVISAT are being processed to monitor surface changes before and after 2000. Changes of groundwater level in the study area were observed, in order to distinguish the amount of land subsidence caused by groundwater withdrawal. The groundwater historical observation data were taken from The USGS National Water Information System (NWIS). The results of the groundwater level between 1990 and 2011 show approximately 0.5 m per year of water decline in the study area. Results of these complementary techniques will help in assessing the possible role of the water pumping from the subsurface on the subsidence in the area.
STS-68 radar image: Glasgow, Missouri
1994-10-07
STS068-S-055 (7 October 1994) --- This is a false-color L-Band image of an area near Glasgow, Missouri, centered at about 39.2 degrees north latitude and 92.8 degrees west longitude. The image was acquired using the L-Band radar channel (horizontally transmitted and received and horizontally transmitted and vertically received) polarization's combined. The data were acquired by the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) aboard the Space Shuttle Endeavour on orbit 50 on October 3, 1994. The area shown is approximately 37 by 25 kilometers (23 by 16 miles). The radar data, coupled with pre-flood aerial photography and satellite data and post-flood topographic and field data, are being used to evaluate changes associated with levee breaks in land forms, where deposits formed during the widespread flooding in 1993 along the Missouri and Mississippi Rivers. The distinct radar scattering properties of farmland, sand fields and scoured areas will be used to inventory flood plains along the Missouri River and determine the processes by which these areas return to preflood conditions. The image shows one such levee break near Glasgow, Missouri. In the upper center of the radar image, below the bend of the river, is a region covered by several meters of sand, shown as dark regions. West (left) of the dark areas, a gap in the levee tree canopy shows the area where the levee failed. Radar data such as these can help scientists more accurately assess the potential for future flooding in this region and how that might impact surrounding communities. Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) is part of NASA's Mission to Planet Earth. The radars illuminate Earth with microwaves, allowing detailed observations at any time, regardless of weather or sunlight conditions. SIR-C/X-SAR uses the three microwave wavelengths: the L-Band (24 centimeters), C-Band (6 centimeters) and X-Band (3 centimeters). The multi-frequency data will be used by the international scientific community to better understand the global environment and how it is changing. The SIR-C/X-SAR data, complemented by aircraft and ground studies, will give scientists clearer insights into those environmental changes which are caused by nature and those changes which are induced by human activity. SIR-C was developed by NASA's Jet Propulsion Laboratory (JPL). X-SAR was developed by the Dornier and Alenia Spazio companies for the German space agency, Deutsche Agentur fuer Raumfahrtangelegenheiten (DARA), and the Italian space agency, Agenzia Spaziale Italiana (ASI), with the Deutsche Forschungsanstalt fuer Luft und Raumfahrt e.v. (DLR), the major partner in science, operations and data processing of X-SAR. (P-44734)
NASA Astrophysics Data System (ADS)
Azza, Gorrab; Zribi, Mehrez; Baghdadi, Nicolas; Mougenot, Bernard; Boulet, Gilles; Lili-Chabaane, Zohra
2015-04-01
Mapping surface soil moisture with meter-scale spatial resolution is appropriate for multi- domains particularly hydrology and agronomy. It allows water resources and irrigation management decisions, drought monitoring and validation of multi-hydrological water balance models. In the last years, various studies have demonstrated the large potential of radar remote sensing data, mainly from C frequency band, to retrieve soil moisture. However, the accuracy of the soil moisture estimation, by inversing backscattering radar coefficients (σ°), is affected by the influence of surface roughness and vegetation biomass contributions. In recent years, different empirical, semi empirical and physical approaches are developed for bare soil conditions, to estimate accurately spatial soil moisture variability. In this study, we propose an approach based on the change detection method for the retrieval of surface soil moisture at a higher spatial resolution. The proposal algorithm combines multi-temporal X-band SAR images (TerraSAR-X) with different continuous thetaprobe measurements. Seven thetaprobe stations are installed at different depths over the central semi arid region of Tunisia (9°23' - 10°17' E, 35° 1'-35°55' N). They cover approximately the entire of our study site and provide regional scale information. Ground data were collected over agricultural bare soil fields simultaneously to various TerraSAR-X data acquired during 2013-2014 and 2014-2015. More than fourteen test fields were selected for each spatial acquisition campaign, with variations in soil texture and in surface soil roughness. For each date, we considered the volumetric water content with thetaprobe instrument and gravimetric sampling; we measured also the roughness parameters with pin profilor. To retrieve soil moisture from X-band SAR data, we analyzed statistically the sensitivity between radar measurements and ground soil moisture derived from permanent thetaprobe stations. Our analyses are applied over bare soil class identified from an optical image SPOT / HRV acquired in the same period of the measurements. Results have shown linear relationship for the radar signals as a function of volumetric soil moisture with high sensitivity about 0.21 dB/vol%. For estimation of change in soil moisture, we considered two options: On the first one, we applied the change detection approach between successive radar images (∆σ°) assuming unchanged soil roughness effects. Our soil moisture retrieval algorithm was validated on the basis of comparisons between estimated and in situ soil moisture measurements over test fields. Using this option, results have shown an accuracy (RMSE) of about 4.8 %. Secondly, we corrected the sensitivity of the radar backscatter images to the surface roughness variability. Results have shown a reduction of the difference between the retrieved soil moisture and ground measurements with an RMSE about 3.7%.
Emergency product generation for disaster management using RISAT and DMSAR quick look SAR processors
NASA Astrophysics Data System (ADS)
Desai, Nilesh; Sharma, Ritesh; Kumar, Saravana; Misra, Tapan; Gujraty, Virendra; Rana, SurinderSingh
2006-12-01
Since last few years, ISRO has embarked upon the development of two complex Synthetic Aperture Radar (SAR) missions, viz. Spaceborne Radar Imaging Satellite (RISAT) and Airborne SAR for Disaster Mangement (DMSAR), as a capacity building measure under country's Disaster Management Support (DMS) Program, for estimating the extent of damage over large areas (~75 Km) and also assess the effectiveness of the relief measures undertaken during natural disasters such as cyclones, epidemics, earthquakes, floods and landslides, forest fires, crop diseases etc. Synthetic Aperture Radar (SAR) has an unique role to play in mapping and monitoring of large areas affected by natural disasters especially floods, owing to its unique capability to see through clouds as well as all-weather imaging capability. The generation of SAR images with quick turn around time is very essential to meet the above DMS objectives. Thus the development of SAR Processors, for these two SAR systems poses considerable challenges and design efforts. Considering the growing user demand and inevitable necessity for a full-fledged high throughput processor, to process SAR data and generate image in real or near-real time, the design and development of a generic SAR Processor has been taken up and evolved, which will meet the SAR processing requirements for both Airborne and Spaceborne SAR systems. This hardware SAR processor is being built, to the extent possible, using only Commercial-Off-The-Shelf (COTS) DSP and other hardware plug-in modules on a Compact PCI (cPCI) platform. Thus, the major thrust has been on working out Multi-processor Digital Signal Processor (DSP) architecture and algorithm development and optimization rather than hardware design and fabrication. For DMSAR, this generic SAR Processor operates as a Quick Look SAR Processor (QLP) on-board the aircraft to produce real time full swath DMSAR images and as a ground based Near-Real Time high precision full swath Processor (NRTP). It will generate full-swath (6 to 75 Kms) DMSAR images in 1m / 3m / 5m / 10m / 30m resolution SAR operating modes. For RISAT mission, this generic Quick Look SAR Processor will be mainly used for browse product generation at NRSA-Shadnagar (SAN) ground receive station. RISAT QLP/NRTP is also proposed to provide an alternative emergency SAR product generation chain. For this, the S/C aux data appended in Onboard SAR Frame Format (x, y, z, x', y', z', roll, pitch, yaw) and predicted orbit from previous days Orbit Determination data will be used. The QLP / NRTP will produce ground range images in real / near real time. For emergency data product generation, additional Off-line tasks like geo-tagging, masking, QC etc needs to be performed on the processed image. The QLP / NRTP would generate geo-tagged images from the annotation data available from the SAR P/L data itself. Since the orbit & attitude information are taken as it is, the location accuracy will be poorer compared to the product generated using ADIF, where smoothened attitude and orbit are made available. Additional tasks like masking, output formatting and Quality checking of the data product will be carried out at Balanagar, NRSA after the image annotated data from QLP / NRTP is sent to Balanagar. The necessary interfaces to the QLP/NRTP for Emergency product generation are also being worked out. As is widely acknowledged, QLP/NRTP for RISAT and DMSAR is an ambitious effort and the technology of future. It is expected that by the middle of next decade, the next generation SAR missions worldwide will have onboard SAR Processors of varying capabilities and generate SAR Data products and Information products onboard instead of SAR raw data. Thus, it is also envisaged that these activities related to QLP/NRTP implementation for RISAT ground segment and DMSAR will be a significant step which will directly feed into the development of onboard real time processing systems for ISRO's future space borne SAR missions. This paper describes the design requirements, configuration details and salient features, apart from highlighting the utility of these Quick Look SAR processors for RISAT and DMSAR, for generation of emergency products for Disaster management.
NASA Astrophysics Data System (ADS)
Notti, Davide; Calò, Fabiana; Cigna, Francesca; Manunta, Michele; Herrera, Gerardo; Berti, Matteo; Meisina, Claudia; Tapete, Deodato; Zucca, Francesco
2015-11-01
Recent advances in multi-temporal Differential Synthetic Aperture Radar (SAR) Interferometry (DInSAR) have greatly improved our capability to monitor geological processes. Ground motion studies using DInSAR require both the availability of good quality input data and rigorous approaches to exploit the retrieved Time Series (TS) at their full potential. In this work we present a methodology for DInSAR TS analysis, with particular focus on landslides and subsidence phenomena. The proposed methodology consists of three main steps: (1) pre-processing, i.e., assessment of a SAR Dataset Quality Index (SDQI) (2) post-processing, i.e., application of empirical/stochastic methods to improve the TS quality, and (3) trend analysis, i.e., comparative implementation of methodologies for automatic TS analysis. Tests were carried out on TS datasets retrieved from processing of SAR imagery acquired by different radar sensors (i.e., ERS-1/2 SAR, RADARSAT-1, ENVISAT ASAR, ALOS PALSAR, TerraSAR-X, COSMO-SkyMed) using advanced DInSAR techniques (i.e., SqueeSAR™, PSInSAR™, SPN and SBAS). The obtained values of SDQI are discussed against the technical parameters of each data stack (e.g., radar band, number of SAR scenes, temporal coverage, revisiting time), the retrieved coverage of the DInSAR results, and the constraints related to the characterization of the investigated geological processes. Empirical and stochastic approaches were used to demonstrate how the quality of the TS can be improved after the SAR processing, and examples are discussed to mitigate phase unwrapping errors, and remove regional trends, noise and anomalies. Performance assessment of recently developed methods of trend analysis (i.e., PS-Time, Deviation Index and velocity TS) was conducted on two selected study areas in Northern Italy affected by land subsidence and landslides. Results show that the automatic detection of motion trends enhances the interpretation of DInSAR data, since it provides an objective picture of the deformation behaviour recorded through TS and therefore contributes to the understanding of the on-going geological processes.
3D Tomographic SAR Imaging in Densely Vegetated Mountainous Rural Areas in China and Sweden
NASA Astrophysics Data System (ADS)
Feng, L.; Muller, J. P., , Prof
2017-12-01
3D SAR Tomography (TomoSAR) and 4D SAR Differential Tomography (Diff-TomoSAR) exploit multi-baseline SAR data stacks to create an important new innovation of SAR Interferometry, to unscramble complex scenes with multiple scatterers mapped into the same SAR cell. In addition to this 3-D shape reconstruction and deformation solution in complex urban/infrastructure areas, and recent cryospheric ice investigations, emerging tomographic remote sensing applications include forest applications, e.g. tree height and biomass estimation, sub-canopy topographic mapping, and even search, rescue and surveillance. However, these scenes are characterized by temporal decorrelation of scatterers, orbital, tropospheric and ionospheric phase distortion and an open issue regarding possible height blurring and accuracy losses for TomoSAR applications particularly in densely vegetated mountainous rural areas. Thus, it is important to develop solutions for temporal decorrelation, orbital, tropospheric and ionospheric phase distortion.We report here on 3D imaging (especially in vertical layers) over densely vegetated mountainous rural areas using 3-D SAR imaging (SAR tomography) derived from data stacks of X-band COSMO-SkyMed Spotlight and L band ALOS-1 PALSAR data stacks over Dujiangyan Dam, Sichuan, China and L and P band airborne SAR data (BioSAR 2008 - ESA) in the Krycklan river catchment, Northern Sweden. The new TanDEM-X 12m DEM is used to assist co - registration of all the data stacks over China first. Then, atmospheric correction is being assessed using weather model data such as ERA-I, MERRA, MERRA-2, WRF; linear phase-topography correction and MODIS spectrometer correction will be compared and ionospheric correction methods are discussed to remove tropospheric and ionospheric delay. Then the new TomoSAR method with the TanDEM-X 12m DEM is described to obtain the number of scatterers inside each pixel, the scattering amplitude and phase of each scatterer and finally extract tomograms (imaging), their 3D positions and motion parameters (deformation). A progress report will be shown on these different aspects.This work is partially supported by the CSC and UCL MAPS Dean prize through a PhD studentship at UCL-MSSL.
Qiu, Qingyan; Wu, Jianping; Liang, Guohua; Liu, Juxiu; Chu, Guowei; Zhou, Guoyi; Zhang, Deqiang
2015-05-01
Acid rain is an environmental problem of increasing concern in China. In this study, a laboratory leaching column experiment with acid forest soil was set up to investigate the responses of soil and soil solution chemistry to simulated acid rain (SAR). Five pH levels of SAR were set: 2.5, 3.0, 3.5, 4.0, and 4.5 (as a control, CK). The results showed that soil acidification would occur when the pH of SAR was ≤3.5. The concentrations of NO₃(-)and Ca(2+) in the soil increased significantly when the pH of SAR fell 3.5. The concentration of SO₄(2-) in the soil increased significantly when the pH of SAR was <4.0. The effects of SAR on soil solution chemistry became increasingly apparent as the experiment proceeded (except for Na(+) and dissolved organic carbon (DOC)). The net exports of NO₃(-), SO₄(2-), Mg(2+), and Ca(2+) increased about 42-86% under pH 2.5 treatment as compared to CK. The Ca(2+) was sensitive to SAR, and the soil could release Ca(2+) through mineral weathering to mitigate soil acidification. The concentration of exchangeable Al(3+) in the soil increased with increasing the acidity of SAR. The releases of soluble Al and Fe were SAR pH dependent, and their net exports under pH 2.5 treatment were 19.6 and 5.5 times, respectively, higher than that under CK. The net export of DOC was reduced by 12-29% under SAR treatments as compared to CK. Our results indicate the chemical constituents in the soil are more sensitive to SAR than those in the soil solution, and the effects of SAR on soil solution chemistry depend not only on the intensity of SAR but also on the duration of SAR addition. The soil and soil solution chemistry in this region may not be affected by current precipitation (pH≈4.5) in short term, but the soil and soil leachate chemistry may change dramatically if the pH of precipitation were below 3.5 and 3.0, respectively.
NASA Astrophysics Data System (ADS)
Arvelyna, Yessy; Oshima, Masaki
2005-01-01
This paper studies the effect of internal wave in the Lombok Strait to chlorophyll distribution in the surrounded areas using ERS SAR, ASTER, SeaWiFS and AVHRR-NOAA images data during 1996-2004 periods. The observation results shows that the internal waves were propagated to the south and the north of strait and mostly occurred during transitional season from dry to wet and wet season (rainy season) between September to December when the layers are strongly stratified. Wavelet transform of image using Meyer wavelet analysis is applied for internal wave detection in ERS SAR and ASTER images, for symmetric extension of data at the image boundaries, to prevent discontinuities by a periodic wrapping of data in fast algorithm and space-saving code. Internal wave created elongated pattern in detail and approximation of image from level 2 to 5 and retained value between 2-4.59 times compared to sea surface, provided accuracy in classification over than 80%. In segmentation process, the Canny edge detector is applied on the approximation image at level two to derive internal wave signature in image. The proposed method can extract the internal wave signature, maintain the continuity of crest line while reduce small strikes from noise. The segmentation result, i.e. the length between crest and trough, is used to compute the internal wave induced current using Korteweg-de Vries (KdV) equation. On ERS SAR data contains surface signature of internal wave (2001/8/20), we calculated that internal wave propagation speed was 1.2 m/s and internal wave induced current was 0.56 m/s, respectively. From the observation of ERS SAR and SeaWiFS images data, we found out that the distribution of maximum chlorophyll area at southern coastline off Bali Island when strong internal wave induced current occurred in south of the Lombok Strait was distributed further to westward, i.e. from 9.25°-10.25°LS, 115°-116.25°SE to 8.8°-10.7°LS, 114.5°-116°SE, and surface chlorophyll concentration near coastal area, i.e. area 8.8°-9.25° LS, 114.5°-115°SE, increased. The preliminary result of this study concludes that the internal waves presumably affect chlorophyll distribution to westward (from 9.25°-10.25°LS, 115°-116.25°SE to 8.8°-10.7°LS, 114.5°-116°SE) in the south coast off Bali Island and increase surface chlorophyll concentration near coastal area (8.8°-9.25° LS, 114.5°-115°SE).
An Adaptive Ship Detection Scheme for Spaceborne SAR Imagery
Leng, Xiangguang; Ji, Kefeng; Zhou, Shilin; Xing, Xiangwei; Zou, Huanxin
2016-01-01
With the rapid development of spaceborne synthetic aperture radar (SAR) and the increasing need of ship detection, research on adaptive ship detection in spaceborne SAR imagery is of great importance. Focusing on practical problems of ship detection, this paper presents a highly adaptive ship detection scheme for spaceborne SAR imagery. It is able to process a wide range of sensors, imaging modes and resolutions. Two main stages are identified in this paper, namely: ship candidate detection and ship discrimination. Firstly, this paper proposes an adaptive land masking method using ship size and pixel size. Secondly, taking into account the imaging mode, incidence angle, and polarization channel of SAR imagery, it implements adaptive ship candidate detection in spaceborne SAR imagery by applying different strategies to different resolution SAR images. Finally, aiming at different types of typical false alarms, this paper proposes a comprehensive ship discrimination method in spaceborne SAR imagery based on confidence level and complexity analysis. Experimental results based on RADARSAT-1, RADARSAT-2, TerraSAR-X, RS-1, and RS-3 images demonstrate that the adaptive scheme proposed in this paper is able to detect ship targets in a fast, efficient and robust way. PMID:27563902
Effect of Antenna Pointing Errors on SAR Imaging Considering the Change of the Point Target Location
NASA Astrophysics Data System (ADS)
Zhang, Xin; Liu, Shijie; Yu, Haifeng; Tong, Xiaohua; Huang, Guoman
2018-04-01
Towards spaceborne spotlight SAR, the antenna is regulated by the SAR system with specific regularity, so the shaking of the internal mechanism is inevitable. Moreover, external environment also has an effect on the stability of SAR platform. Both of them will cause the jitter of the SAR platform attitude. The platform attitude instability will introduce antenna pointing error on both the azimuth and range directions, and influence the acquisition of SAR original data and ultimate imaging quality. In this paper, the relations between the antenna pointing errors and the three-axis attitude errors are deduced, then the relations between spaceborne spotlight SAR imaging of the point target and antenna pointing errors are analysed based on the paired echo theory, meanwhile, the change of the azimuth antenna gain is considered as the spotlight SAR platform moves ahead. The simulation experiments manifest the effects on spotlight SAR imaging caused by antenna pointing errors are related to the target location, that is, the pointing errors of the antenna beam will severely influence the area far away from the scene centre of azimuth direction in the illuminated scene.
Understanding the T cell immune response in SARS coronavirus infection
Janice Oh, Hsueh-Ling; Ken-En Gan, Samuel; Bertoletti, Antonio; Tan, Yee-Joo
2012-01-01
The severe acute respiratory syndrome (SARS) epidemic started in late 2002 and swiftly spread across 5 continents with a mortality rate of around 10%. Although the epidemic was eventually controlled through the implementation of strict quarantine measures, there continues a need to investigate the SARS coronavirus (SARS-CoV) and develop interventions should it re-emerge. Numerous studies have shown that neutralizing antibodies against the virus can be found in patients infected with SARS-CoV within days upon the onset of illness and lasting up to several months. In contrast, there is little data on the kinetics of T cell responses during SARS-CoV infection and little is known about their role in the recovery process. However, recent studies in mice suggest the importance of T cells in viral clearance during SARS-CoV infection. Moreover, a growing number of studies have investigated the memory T cell responses in recovered SARS patients. This review covers the available literature on the emerging importance of T cell responses in SARS-CoV infection, particularly on the mapping of cytotoxic T lymphocyte (CTL) epitopes, longevity, polyfunctionality and human leukocyte antigen (HLA) association as well as their potential implications on treatment and vaccine development. PMID:26038429
Understanding the T cell immune response in SARS coronavirus infection.
Janice Oh, Hsueh-Ling; Ken-En Gan, Samuel; Bertoletti, Antonio; Tan, Yee-Joo
2012-09-01
The severe acute respiratory syndrome (SARS) epidemic started in late 2002 and swiftly spread across 5 continents with a mortality rate of around 10%. Although the epidemic was eventually controlled through the implementation of strict quarantine measures, there continues a need to investigate the SARS coronavirus (SARS-CoV) and develop interventions should it re-emerge. Numerous studies have shown that neutralizing antibodies against the virus can be found in patients infected with SARS-CoV within days upon the onset of illness and lasting up to several months. In contrast, there is little data on the kinetics of T cell responses during SARS-CoV infection and little is known about their role in the recovery process. However, recent studies in mice suggest the importance of T cells in viral clearance during SARS-CoV infection. Moreover, a growing number of studies have investigated the memory T cell responses in recovered SARS patients. This review covers the available literature on the emerging importance of T cell responses in SARS-CoV infection, particularly on the mapping of cytotoxic T lymphocyte (CTL) epitopes, longevity, polyfunctionality and human leukocyte antigen (HLA) association as well as their potential implications on treatment and vaccine development.
Radar image and data fusion for natural hazards characterisation
Lu, Zhong; Dzurisin, Daniel; Jung, Hyung-Sup; Zhang, Jixian; Zhang, Yonghong
2010-01-01
Fusion of synthetic aperture radar (SAR) images through interferometric, polarimetric and tomographic processing provides an all - weather imaging capability to characterise and monitor various natural hazards. This article outlines interferometric synthetic aperture radar (InSAR) processing and products and their utility for natural hazards characterisation, provides an overview of the techniques and applications related to fusion of SAR/InSAR images with optical and other images and highlights the emerging SAR fusion technologies. In addition to providing precise land - surface digital elevation maps, SAR - derived imaging products can map millimetre - scale elevation changes driven by volcanic, seismic and hydrogeologic processes, by landslides and wildfires and other natural hazards. With products derived from the fusion of SAR and other images, scientists can monitor the progress of flooding, estimate water storage changes in wetlands for improved hydrological modelling predictions and assessments of future flood impacts and map vegetation structure on a global scale and monitor its changes due to such processes as fire, volcanic eruption and deforestation. With the availability of SAR images in near real - time from multiple satellites in the near future, the fusion of SAR images with other images and data is playing an increasingly important role in understanding and forecasting natural hazards.
Interferometric synthetic aperture radar (InSAR)—its past, present and future
Lu, Zhong; Kwoun, Oh-Ig; Rykhus, R.P.
2007-01-01
Very simply, interferometric synthetic aperture radar (InSAR) involves the use of two or more synthetic aperture radar (SAR) images of the same area to extract landscape topography and its deformation patterns. A SAR system transmits electromagnetic waves at a wavelength that can range from a few millimeters to tens of centimeters and therefore can operate during day and night under all-weather conditions. Using SAR processing technique (Curlander and McDonough, 1991), both the intensity and phase of the reflected (or backscattered) radar signal of each ground resolution element (a few meters to tens of meters) can be calculated in the form of a complex-valued SAR image that represents the reflectivity of the ground surface. The amplitude or intensity of the SAR image is determined primarily by terrain slope, surface roughness, and dielectric constants, whereas the phase of the SAR image is determined primarily by the distance between the satellite antenna and the ground targets. InSAR imaging utilizes the interaction of electromagnetic waves, referred to as interference, to measure precise distances between the satellite antenna and ground resolution elements to derive landscape topography and its subtle change in elevation.
SARS-associated Coronavirus Transmitted from Human to Pig
Chen, Weijun; Yan, Minghua; Yang, Ling; Ding, Boliang; He, Bo; Wang, Yingzhen; Liu, Xiuli; Liu, Chenhui; Zhu, Hui; You, Bo; Huang, Shengyong; Zhang, Jiangguo; Mu, Feng; Xiang, Zhao; Feng, Xiaoli; Wen, Jie; Fang, Jianqiu; Yu, Jun; Yang, Huanming
2005-01-01
Severe acute respiratory syndrome–associated coronavirus (SARS-CoV) was isolated from a pig during a survey for possible routes of viral transmission after a SARS epidemic. Sequence and epidemiology analyses suggested that the pig was infected by a SARS-CoV of human origin. PMID:15757562
12 CFR 163.180 - Suspicious Activity Reports and other reports and statements.
Code of Federal Regulations, 2014 CFR
2014-01-01
... Suspicious Activity Report. (3) SARs required. A savings association or service corporation shall file a SAR... other institution-affiliated parties to supervisory action. (11) Obtaining SARs. A savings association or service corporation may obtain SARs and the instructions from the appropriate Federal banking...
12 CFR 163.180 - Suspicious Activity Reports and other reports and statements.
Code of Federal Regulations, 2013 CFR
2013-01-01
... Suspicious Activity Report. (3) SARs required. A savings association or service corporation shall file a SAR... other institution-affiliated parties to supervisory action. (11) Obtaining SARs. A savings association or service corporation may obtain SARs and the instructions from the appropriate Federal banking...
12 CFR 163.180 - Suspicious Activity Reports and other reports and statements.
Code of Federal Regulations, 2012 CFR
2012-01-01
... Suspicious Activity Report. (3) SARs required. A savings association or service corporation shall file a SAR... other institution-affiliated parties to supervisory action. (11) Obtaining SARs. A savings association or service corporation may obtain SARs and the instructions from the appropriate Federal banking...
20. OVERVIEW OF SAR3 COMPLEX, SHOWING FORMER RESIDENTIAL AREA, SAR3 ...
20. OVERVIEW OF SAR-3 COMPLEX, SHOWING FORMER RESIDENTIAL AREA, SAR-3 SWITCH RACK, MAINTENANCE YARD, AND GREENSPOT BRIDGE. NOTE ALSO LARGE PIPE CONDUCTING TAILRACE WATER INTO IRRIGATION SYSTEM. VIEW TO SOUTHWEST. - Santa Ana River Hydroelectric System, Redlands, San Bernardino County, CA
Analysis of Wind and Sea State in SAR data of Hurricanes
NASA Astrophysics Data System (ADS)
Hoja, D.; Schulz-Stellenfleth, J.; Lehner, S.; Horstmann, J.
2003-04-01
Spaceborne synthetic aperture radar (SAR) is still the only instrument providing directional ocean wave and in addition surface wind information on a global and continuous basis. Operating in ASAR wave mode ENVISAT, launched in 2002, provides 10 km x 5 km SAR images every 100 km along the orbit. These SAR data continue and expand the SAR era of the European Remote Sensing satellites ERS-1 and ERS-2, which have acquired similar SAR data since 1991 on a global basis. To not only use the official ERS SAR wave mode product, which consists only of the SAR image power spectrum, but also the full SAR image information a subset of 27 days globally distributed ERS-2 SAR raw data were processed to single look complex SAR imagettes using the BSAR processor developed at the German Aerospace Center. These data have the same format as the official ESA product for ENVISAT ASAR wave mode data. This subset of 34,000 ERS-2 SAR imagettes was used to develop and validate algorithms for wind and wave retrieval, which are also applicable to ENVISAT ASAR wave mode data. The time frame of the dataset covers several tropical cyclones in the Atlantic Ocean of which hurricane Fran has been investigated in detail together with additional data available from scatterometers, buoys and weather centers. Hurricane Fran was active from August 23 to September 8, 1996. During this time, hurricane Fran developed near the African coast and progressed over the North Atlantic Ocean. Landfall occurred on September 5, 1996 at the coast of North Carolina, USA. Fran was part of a whole series of tropical cyclones travelling about the same course in a short time. The wind is extracted from SAR imagery and compared to results of the numerical model output provided by the European Center for Medium-Range Weather Forecast (ECMWF) and co-located ERS-2 scatterometer measurements. The Swell and wind sea systems generated by the tropical cyclones are measured using SAR cross spectra and a newly developed partitioning technique. For each component wave system (partition) spectral parameters like wavelength and wave propagation direction are calculated and compared to numerical model output provided by ECMWF. The progression of the tropical cyclones is presented and it is described, how the hurricanes are portrayed in the SAR data. The response of waves to fast turning winds is analyzed. Conclusions are drawn about the wave model forecast in hurricane situations using satellite wave mode data. Keywords: Hurricanes, SAR, ocean winds, ocean waves, wind sea and swell
NASA Technical Reports Server (NTRS)
Rincon, Rafael F.; Fatoyinbo, Temilola; Ranson, K. Jon; Osmanoglu, Batuhan; Sun, Guoqing; Deshpande, Manohar D.; Perrine, Martin L.; Du Toit, Cornelis F.; Bonds, Quenton; Beck, Jaclyn;
2014-01-01
EcoSAR is a new synthetic aperture radar (SAR) instrument being developed at the NASA/ Goddard Space Flight Center (GSFC) for the polarimetric and interferometric measurements of ecosystem structure and biomass. The instrument uses a phased-array beamforming architecture and supports full polarimetric measurements and single pass interferometry. This Instrument development is part of NASA's Earth Science Technology Office Instrument Incubator Program (ESTO IIP).
Reinke, Lennart Michel; Hartleib, Anika; Nehlmeier, Inga; Gierer, Stefanie; Hoffmann, Markus; Hofmann-Winkler, Heike; Winkler, Michael
2017-01-01
The spike (S) protein of severe acute respiratory syndrome coronavirus (SARS-CoV) mediates viral entry into target cells. Cleavage and activation of SARS S by a host cell protease is essential for infectious viral entry and the responsible enzymes are potential targets for antiviral intervention. The type II transmembrane serine protease TMPRSS2 cleaves and activates SARS S in cell culture and potentially also in the infected host. Here, we investigated which determinants in SARS S control cleavage and activation by TMPRSS2. We found that SARS S residue R667, a previously identified trypsin cleavage site, is also required for S protein cleavage by TMPRSS2. The cleavage fragments produced by trypsin and TMPRSS2 differed in their decoration with N-glycans, suggesting that these proteases cleave different SARS S glycoforms. Although R667 was required for SARS S cleavage by TMPRSS2, this residue was dispensable for TMPRSS2-mediated S protein activation. Conversely, residue R797, previously reported to be required for SARS S activation by trypsin, was dispensable for S protein cleavage but required for S protein activation by TMPRSS2. Collectively, these results show that different residues in SARS S control cleavage and activation by TMPRSS2, suggesting that these processes are more complex than initially appreciated. PMID:28636671
Reinke, Lennart Michel; Spiegel, Martin; Plegge, Teresa; Hartleib, Anika; Nehlmeier, Inga; Gierer, Stefanie; Hoffmann, Markus; Hofmann-Winkler, Heike; Winkler, Michael; Pöhlmann, Stefan
2017-01-01
The spike (S) protein of severe acute respiratory syndrome coronavirus (SARS-CoV) mediates viral entry into target cells. Cleavage and activation of SARS S by a host cell protease is essential for infectious viral entry and the responsible enzymes are potential targets for antiviral intervention. The type II transmembrane serine protease TMPRSS2 cleaves and activates SARS S in cell culture and potentially also in the infected host. Here, we investigated which determinants in SARS S control cleavage and activation by TMPRSS2. We found that SARS S residue R667, a previously identified trypsin cleavage site, is also required for S protein cleavage by TMPRSS2. The cleavage fragments produced by trypsin and TMPRSS2 differed in their decoration with N-glycans, suggesting that these proteases cleave different SARS S glycoforms. Although R667 was required for SARS S cleavage by TMPRSS2, this residue was dispensable for TMPRSS2-mediated S protein activation. Conversely, residue R797, previously reported to be required for SARS S activation by trypsin, was dispensable for S protein cleavage but required for S protein activation by TMPRSS2. Collectively, these results show that different residues in SARS S control cleavage and activation by TMPRSS2, suggesting that these processes are more complex than initially appreciated.
NASA Astrophysics Data System (ADS)
Canters, R. A. M.; Franckena, M.; van der Zee, J.; van Rhoon, G. C.
2011-01-01
During deep hyperthermia treatment, patient pain complaints due to heating are common when maximizing power. Hence, there exists a good rationale to investigate whether the locations of predicted SAR peaks by hyperthermia treatment planning (HTP) are correlated with the locations of patient pain during treatment. A retrospective analysis was performed, using the treatment reports of 35 patients treated with deep hyperthermia controlled by extensive treatment planning. For various SAR indicators, the average distance from a SAR peak to a patient discomfort location was calculated, for each complaint. The investigated V0.1 closest (i.e. the part of the 0.1th SAR percentile closest to the patient complaint) performed the best, and leads to an average distance between the SAR peak and the complaint location of 3.9 cm. Other SAR indicators produced average distances that were all above 10 cm. Further, the predicted SAR peak location with V0.1 provides a 77% match with the region of complaint. The current study demonstrates that HTP is able to provide a global indication of the regions where hotspots during treatment will most likely occur. Further development of this technology is necessary in order to use HTP as a valuable toll for objective and advanced SAR steering. The latter is especially valid for applications that enable 3D SAR steering.
Martin, Adrian; Schiavi, Emanuele; Eryaman, Yigitcan; Herraiz, Joaquin L; Gagoski, Borjan; Adalsteinsson, Elfar; Wald, Lawrence L; Guerin, Bastien
2016-06-01
A new framework for the design of parallel transmit (pTx) pulses is presented introducing constraints for local and global specific absorption rate (SAR) in the presence of errors in the radiofrequency (RF) transmit chain. The first step is the design of a pTx RF pulse with explicit constraints for global and local SAR. Then, the worst possible SAR associated with that pulse due to RF transmission errors ("worst-case SAR") is calculated. Finally, this information is used to re-calculate the pulse with lower SAR constraints, iterating this procedure until its worst-case SAR is within safety limits. Analysis of an actual pTx RF transmit chain revealed amplitude errors as high as 8% (20%) and phase errors above 3° (15°) for spokes (spiral) pulses. Simulations show that using the proposed framework, pulses can be designed with controlled "worst-case SAR" in the presence of errors of this magnitude at minor cost of the excitation profile quality. Our worst-case SAR-constrained pTx design strategy yields pulses with local and global SAR within the safety limits even in the presence of RF transmission errors. This strategy is a natural way to incorporate SAR safety factors in the design of pTx pulses. Magn Reson Med 75:2493-2504, 2016. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.
Cynomolgus Macaque as an Animal Model for Severe Acute Respiratory Syndrome
Lawler, James V; Endy, Timothy P; Hensley, Lisa E; Garrison, Aura; Fritz, Elizabeth A; Lesar, May; Baric, Ralph S; Kulesh, David A; Norwood, David A; Wasieloski, Leonard P; Ulrich, Melanie P; Slezak, Tom R; Vitalis, Elizabeth; Huggins, John W; Jahrling, Peter B; Paragas, Jason
2006-01-01
Background The emergence of severe acute respiratory syndrome (SARS) in 2002 and 2003 affected global health and caused major economic disruption. Adequate animal models are required to study the underlying pathogenesis of SARS-associated coronavirus (SARS-CoV) infection and to develop effective vaccines and therapeutics. We report the first findings of measurable clinical disease in nonhuman primates (NHPs) infected with SARS-CoV. Methods and Findings In order to characterize clinically relevant parameters of SARS-CoV infection in NHPs, we infected cynomolgus macaques with SARS-CoV in three groups: Group I was infected in the nares and bronchus, group II in the nares and conjunctiva, and group III intravenously. Nonhuman primates in groups I and II developed mild to moderate symptomatic illness. All NHPs demonstrated evidence of viral replication and developed neutralizing antibodies. Chest radiographs from several animals in groups I and II revealed unifocal or multifocal pneumonia that peaked between days 8 and 10 postinfection. Clinical laboratory tests were not significantly changed. Overall, inoculation by a mucosal route produced more prominent disease than did intravenous inoculation. Half of the group I animals were infected with a recombinant infectious clone SARS-CoV derived from the SARS-CoV Urbani strain. This infectious clone produced disease indistinguishable from wild-type Urbani strain. Conclusions SARS-CoV infection of cynomolgus macaques did not reproduce the severe illness seen in the majority of adult human cases of SARS; however, our results suggest similarities to the milder syndrome of SARS-CoV infection characteristically seen in young children. PMID:16605302
17 CFR 229.402 - (Item 402) Executive compensation.
Code of Federal Regulations, 2014 CFR
2014-04-01
... rights (“SARs”) refers to SARs payable in cash or stock, including SARs payable in cash or stock at the... without tandem SARs (including awards that subsequently have been transferred), the aggregate grant date..., the registrant has adjusted or amended the exercise price of options or SARs previously awarded to a...
78 FR 3399 - Draft 2012 Marine Mammal Stock Assessment Reports
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-16
... mammal stock assessment reports (SARs) in accordance with the Marine Mammal Protection Act, and solicited public comment on draft 2012 SARs. Subsequently, SARs for ten stocks of marine mammals in the Atlantic... solicits public comments on revised draft 2012 SARs for these ten stocks. DATES: Comments must be received...
77 FR 24205 - Proposed Agency Information Collection Activities; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-23
... 1818(s). SARs are exempt from Freedom of Information Act (FOIA) disclosure by 31 U.S.C. 5319 and FIOA... a transaction that is the subject of a SAR. Finally, information contained in SARs may be exempt... transactions. To fulfill these requirements, supervised banking organizations file SARs. Law enforcement...
75 FR 46912 - Draft 2010 Marine Mammal Stock Assessment Reports
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-04
... reviewed the Alaska, Atlantic, and Pacific regional marine mammal stock assessment reports (SARs) in accordance with the Marine Mammal Protection Act. SARs for marine mammals in the Alaska, Atlantic, and... SARs. DATES: Comments must be received by November 2, 2010. ADDRESSES: The 2010 draft SARs, summaries...
SARS Risk Perception, Knowledge, Precautions, and Information Sources, the Netherlands
Aro, Arja R.; Oenema, Anke; de Zwart, Onno; Richardus, Jan Hendrik; Bishop, George D.
2004-01-01
Severe acute respiratory syndrome (SARS)–related risk perceptions, knowledge, precautionary actions, and information sources were studied in the Netherlands during the 2003 SARS outbreak. Although respondents were highly aware of the SARS outbreak, the outbreak did not result in unnecessary precautionary actions or fears. PMID:15496256
10 CFR 72.214 - List of approved spent fuel storage casks.
Code of Federal Regulations, 2012 CFR
2012-01-01
... specified in their Certificates of Compliance. Certificate Number: 1000 SAR Submitted by: General Nuclear Systems, Inc. SAR Title: Topical Safety Analysis Report for the Castor V/21 Cask Independent Spent Fuel... Model Number: CASTOR V/21 Certificate Number: 1002 SAR Submitted by: Nuclear Assurance Corporation SAR...
10 CFR 72.214 - List of approved spent fuel storage casks.
Code of Federal Regulations, 2014 CFR
2014-01-01
... specified in their Certificates of Compliance. Certificate Number: 1000 SAR Submitted by: General Nuclear Systems, Inc. SAR Title: Topical Safety Analysis Report for the Castor V/21 Cask Independent Spent Fuel... Model Number: CASTOR V/21 Certificate Number: 1002 SAR Submitted by: Nuclear Assurance Corporation SAR...
10 CFR 72.214 - List of approved spent fuel storage casks.
Code of Federal Regulations, 2013 CFR
2013-01-01
... specified in their Certificates of Compliance. Certificate Number: 1000 SAR Submitted by: General Nuclear Systems, Inc. SAR Title: Topical Safety Analysis Report for the Castor V/21 Cask Independent Spent Fuel... Model Number: CASTOR V/21 Certificate Number: 1002 SAR Submitted by: Nuclear Assurance Corporation SAR...
Card, Marcella L; Gomez-Alvarez, Vicente; Lee, Wen-Hsiung; Lynch, David G; Orentas, Nerija S; Lee, Mari Titcombe; Wong, Edmund M; Boethling, Robert S
2017-03-22
Chemical property estimation is a key component in many industrial, academic, and regulatory activities, including in the risk assessment associated with the approximately 1000 new chemical pre-manufacture notices the United States Environmental Protection Agency (US EPA) receives annually. The US EPA evaluates fate, exposure and toxicity under the 1976 Toxic Substances Control Act (amended by the 2016 Frank R. Lautenberg Chemical Safety for the 21 st Century Act), which does not require test data with new chemical applications. Though the submission of data is not required, the US EPA has, over the past 40 years, occasionally received chemical-specific data with pre-manufacture notices. The US EPA has been actively using this and publicly available data to develop and refine predictive computerized models, most of which are housed in EPI Suite™, to estimate chemical properties used in the risk assessment of new chemicals. The US EPA develops and uses models based on (quantitative) structure-activity relationships ([Q]SARs) to estimate critical parameters. As in any evolving field, (Q)SARs have experienced successes, suffered failures, and responded to emerging trends. Correlations of a chemical structure with its properties or biological activity were first demonstrated in the late 19 th century and today have been encapsulated in a myriad of quantitative and qualitative SARs. The development and proliferation of the personal computer in the late 20 th century gave rise to a quickly increasing number of property estimation models, and continually improved computing power and connectivity among researchers via the internet are enabling the development of increasingly complex models.
Ji, Lingyun; Lu, Zhong; Dzurisin, Daniel; Senyukov, Sergey
2013-01-01
Interferometric synthetic aperture radar (InSAR) images reveal a pre-eruption deformation signal at Kizimen volcano, Kamchatka, Russia, where an ongoing eruption began in mid-November, 2010. The previous eruption of this basaltic andesite-to-dacite stratovolcano occurred in 1927–1928. InSAR images from both ascending and descending orbital passes of Envisat and ALOS PALSAR satellites show as much as 6 cm of line-of-sight shortening from September 2008 to September 2010 in a broad area centered at Kizimen. About 20 cm of opening of a nearly vertical dike provides an adequate fit to the surface deformation pattern. The model dike is approximately 14 km long, 10 km high, centered 13 km beneath Kizimen, and strikes NE–SW. Time-series analysis of multi-temporal interferograms indicates that (1) intrusion started sometime between late 2008 and July 2009, (2) continued at a nearly constant rate, and (3) resulted in a volume expansion of 3.2 × 107 m3 by September 2010, i.e., about two months before the onset of the 2010 eruption. Earthquakes located above the tip of the dike accompanied the intrusion. Eventually, magma pressure in the dike exceeded the confining strength of the host rock, triggering the 2010 eruption. Our results provide insight into the intrusion process that preceded an explosive eruption at a Pacific Rim stratovolcano following nearly a century of quiescence, and therefore have implications for monitoring and hazards assessment at similar volcanoes elsewhere.
NASA Astrophysics Data System (ADS)
La Marra, Daniele; Poland, Michael P.; Acocella, Valerio; Battaglia, Maurizio; Miklius, Asta
2016-04-01
Geodesy allows detecting the deformation of volcanoes, thus understanding magmatic processes. This becomes particularly efficient when time series are available and volcanoes can be monitored on the mean-term (decades), and not only during a specific event. Here we exploit the SBAS technique, using SAR images from ENVISAT (descending and ascending orbits; 2003 - 2010) and COSMO-SkyMed (descending and ascending orbits; 2012 - 2014), to study a decade of deformation at Mauna Loa (Hawaii). These data are merged time series data from 24 continuously operating GPS stations, which allows us to calibrate the InSAR time series. Our results show a long-term inflation of the volcano from 2003 to 2014, reaching a peak of ~11 cm/yr on the summit area between mid-2004 to mid-2005 and then slowing down. Within this frame, we were able to identify five main periods with approximately linear deformation behavior. The inversion of the deformation data in the first four periods suggests the repeated, though not constant, intrusion of one or more dikes below the summit caldera and the upper Southwest Rift Zone. Moreover, the dike intrusion coincides with minor acceleration of flank slip. Such a behavior is distinctive and, with the exception of the nearby Kilauea, has not been observed at any other volcano on the mean term. It is proposed that continuous, even though not constant flank instability of the SE flank may promote semi-continuous intrusions in a volcano with a ready magma supply.
Munday, John S; Thomson, Neroli; Dunowska, Magda; Knight, Cameron G; Laurie, Rebecca E; Hills, Simon
2015-06-12
Feline sarcoids are rare mesenchymal neoplasms of domestic and exotic cats. Previous studies have consistently detected short DNA sequences from a papillomavirus (PV), designated feline sarcoid-associated papillomavirus (FeSarPV), in these neoplasms. The FeSarPV sequence has never been detected in any non-sarcoid sample from cats but has been amplified from the skin of cattle suggesting that feline sarcoids are caused by cross-species infection by a bovine papillomavirus (BPV). The aim of the present study was to determine the genome of the PV that contains the FeSarPV sequence. Using the circular nature of PV DNA, four specifically designed 'outward facing' primers were used to amplify two approximately 4,000 bp DNA segments from a feline sarcoid. The two PCR products were sequenced using next generation sequencing and the full genome of the PV, consisting 7,966 bp, was assembled and analysed. Phylogenetic analysis revealed the PV was closely related to the species 4 delta BPVs-1, -2, and -13, but distantly related to any carnivoran PV genus. These results are consistent with feline sarcoids being caused by a BPV type and we propose a classification of BPV-14 for this novel PV. Initial analysis suggests that, like other delta BPVs, the BPV-14 E5 protein could cause mesenchymal proliferation by binding to the platelet derived growth factor beta receptor. Interestingly BPV-14 has not been detected in any equine sarcoid suggesting that BPV-14 has a host range that is limited to bovids and felids. Copyright © 2015 Elsevier B.V. All rights reserved.
Guérin, Bastien; Stockmann, Jason P; Baboli, Mehran; Torrado-Carvajal, Angel; Stenger, Andrew V; Wald, Lawrence L
2016-08-01
To design parallel transmission spokes pulses with time-shifted profiles for joint mitigation of intensity variations due to B1+ effects, signal loss due to through-plane dephasing, and the specific absorption rate (SAR) at 7T. We derived a slice-averaged small tip angle (SA-STA) approximation of the magnetization signal at echo time that depends on the B1+ transmit profiles, the through-slice B0 gradient and the amplitude and time-shifts of the spoke waveforms. We minimize a magnitude least-squares objective based on this signal equation using a fast interior-point approach with analytical expressions of the Jacobian and Hessian. Our algorithm runs in less than three minutes for the design of two-spoke pulses subject to hundreds of local SAR constraints. On a B0/B1+ head phantom, joint optimization of the channel-dependent time-shifts and spoke amplitudes allowed signal recovery in high-B0 regions at no increase of SAR. Although the method creates uniform magnetization profiles (ie, uniform intensity), the flip angle varies across the image, which makes it ill-suited to T1-weighted applications. The SA-STA approach presented in this study is best suited to T2*-weighted applications with long echo times that require signal recovery around high B0 regions. Magn Reson Med 76:540-554, 2016. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.
NASA Astrophysics Data System (ADS)
Triggiani, M.; Refice, A.; Capolongo, D.; Bovenga, F.; Caldara, M.
2009-04-01
We present results of an experiment aimed at detecting possible displacements due to subsidence in the coastal area of the Tavoliere plain, Puglia Region, in Southern Italy, through analysis of remotely sensed data. The Tavoliere is the second largest Italian plain. Its coastal area, between the urban centers of Manfredonia and Barletta, is composed of a 50 km long sandy beach (Manfredonia gulf), linking the Gargano massif at north with the Murge plateau in the south-east. Both areas belong to the carbonate Mesozoic Apulian platform. The current configuration of the Gulf was reached recently, as a consequence of the Holocene sea level rise. During the Neolithic age the plain was occupied by an elongated lagoon (Salpi Lagoon) [1]. During the 2nd century B.C., alluvial deposition caused the lagoon to be separated into two basins: the so-called Salpi lake at south and the Salso lake at north. To cope with the increasing demand of arable lands and with the necessity to make unhealthy areas accessible to humans, some reclaims were accomplished by diverting and channelling the rivers crossing the Tavoliere plain, and by levelling dune belts. At present, the beach is separated by low artificial dunes from the areas already reclaimed and intensely cultivated or exploited as evaporation basin for salt production. In the last decades, the coastal area has been retreating due to a reduction in sediment input necessary for coastal equilibrium. The levelling of dunes and the decrease of fluvial turbid discharge due to dam constructions are probably the cause of this deficit in sediment supply. During highly intense hydrodynamic and meteorological events, sea waters often penetrate deeply inland, flooding intensively cultivated areas. These events are occurring with growing frequency and rates. They are an indication of the possibility that those areas are subject to subsidence at a faster rate in comparison to the surroundings. An example is the salt marsh located inland of the tourist sea village "Ippocampo". Here, unpublished studies based on ground data indicate average subsidence rates of the order of 0.20 mm/y in the last 125 ka for the inland area next to the village. More recently, height maps issued by the Italian Military Geographic Institute (IGM) in the 1950s report heights a.s.l. of the order of a few m. Observing that today the area is practically at sea level, an average subsidence of the order of tens of mm/y can be inferred for the last 50 years. To gain insight into the recent evolution of these phenomena, we investigate vertical movements on the coastal Tavoliere area through multitemporal differential Interferometric synthetic aperture radar (DInSAR) techniques. We use a persistent scatterers interferometry (PSI) processing methodology [2] to estimate subsidence displacement rates from long temporal series of SAR acquisitions. PSI techniques, first developed at POLIMI [3], allow to retrieve phase information from stacks of co-registered SAR interferograms spanning many years and taken from different directions with large baselines, by restricting the analysis to selected image pixels containing single objects with strong radar backscatter returns. Exploiting the high temporal stability of radar returns from these targets, it is possible to correct the images from spurious phase contributions such as atmospheric phase artefacts and errors in the digital elevation models used to account for topographic InSAR phase. Such stable objects typically coincide with man-made features, so successful applications of PSI techniques are mainly reported over urban centers. We processed a total of 105 SAR images acquired from the ERS-1/2 and ENVISAT satellites, organized in 3 stacks related to both descending (50 ERS-1/2 scenes) and ascending (25 ERS-1/2 and 30 ENVISAT scenes) acquisition geometries. The acquisitions refer to the temporal periods from 1995 to 2000 (ERS) and 2003 to 2008 (ENVISAT), respectively, with a temporal repetition frequency of roughly 1 acquisition every 35 days. The 3 stacks, covering approximately the same ground area centred on the Tavoliere coastal plain, were processed independently. Reliable phase measurements were obtained over small urban centers and anthropogenic features scattered along the coast. Results from all 3 stacks indicate the presence of displacements occurring through the entire temporal interval of observation. In particular, displacements appear spatially organized as a subsidence "bowl" centered approximately around the area of Zapponeta, with maximum subsidence rates exceeding 20 mm/y. The detected displacements appear consistent with the average rates deduced heuristically from analysis of the environmental settings as exposed above. Moreover, they also qualitatively agree with other investigations performed using analogous techniques and data over the region (e.g. [4]). Possible interpretation of these results can be attempted by considering that the area has been repeatedly subject to reclaiming through filling, and that the deposited sediments are most exposed to compaction. Moreover, the area is subject to intense water extraction, which further enhances the effects of sediment compaction. Validation of the obtained measurements is in progress through extended data analysis and in situ activities. However, these preliminary analyses and comparisons between InSAR and ground data hint to the possible presence of two co-existing subsidence phenomena in the area: a natural subsidence due to tectonics or isostatic rebound, with slow subsidence effects occurring over geologic time scales, with an additional, more pronounced subsidence phenomenon on the recent sediment deposits due to sediment compaction under lithostatic loading, and an anthropogenic local, accelerated subsidence on the lowest areas, due to intensive draining mostly for irrigation purposes, which adds to recent land remediation actions to cause a worrisome lowering of the water table in the area. References [1] F. Boenzi, M. Caldara, M. Moresi, L. Pennetta 2002, "History of the Salpi lagoon-sabhka (Manfredonia Gulf, Italy)". Il Quaternario, 14, 93-104. 2001 [2] F. Bovenga, A. Refice, R. Nutricato, L. Guerriero, M.T. Chiaradia, "SPINUA: a flexible processing chain for ERS / ENVISAT long term interferometry", Proceedings of ESA-ENVISAT Symposium, Salzburg, Austria, 6-10 September, 2004. [3] Ferretti, A., Prati, C., Rocca, F. "Permanent Scatterers in SAR Interferometry". IEEE Transactions on Geoscience and Remote Sensing 39, 8-20, 2001. [4] S. Salvi, S. Atzori, C.A. Brunori, F. Doumaz, G.P. Ricciardi, G. Solaro, S. Stramondo, C. Tolomei, R. Lanari, A. Pepe, A. Ferretti, S. Cespa, "The VELISAR initiative for the measurement of ground velocity in italian seismogenic areas", EGU General Assembly, Wien, Austria, 15-20 April, 2007.
Wu, Chung-Yu; Cheng, Cheng-Hsiang; Chen, Zhi-Xin
2018-06-01
In this paper, a 16-channel analog front-end (AFE) electrocorticography signal acquisition circuit for a closed-loop seizure control system is presented. It is composed of 16 input protection circuits, 16 auto-reset chopper-stabilized capacitive-coupled instrumentation amplifiers (AR-CSCCIA) with bandpass filters, 16 programmable transconductance gain amplifiers, a multiplexer, a transimpedance amplifier, and a 128-kS/s 10-bit delta-modulated successive-approximation-register analog-to-digital converter (SAR ADC). In closed-loop seizure control system applications, the stimulator shares the same electrode with the AFE amplifier for effective suppression of epileptic seizures. To prevent from overstress in MOS devices caused by high stimulation voltage, an input protection circuit with a high-voltage-tolerant switch is proposed for the AFE amplifier. Moreover, low input-referred noise is achieved by using the chopper modulation technique in the AR-CSCCIA. To reduce the undesired effects of chopper modulation, an improved offset reduction loop is proposed to reduce the output offset generated by input chopper mismatches. The digital ripple reduction loop is also used to reduce the chopper ripple. The fabricated AFE amplifier has 49.1-/59.4-/67.9-dB programmable gain and 2.02-μVrms input referred noise in a bandwidth of 0.59-117 Hz. The measured power consumption of the AFE amplifier is 3.26 μW per channel, and the noise efficiency factor is 3.36. The in vivo animal test has been successfully performed to verify the functions. It is shown that the proposed AFE acquisition circuit is suitable for implantable closed-loop seizure control systems.
Design of a CMOS readout circuit on ultra-thin flexible silicon chip for printed strain gauges
NASA Astrophysics Data System (ADS)
Elsobky, Mourad; Mahsereci, Yigit; Keck, Jürgen; Richter, Harald; Burghartz, Joachim N.
2017-09-01
Flexible electronics represents an emerging technology with features enabling several new applications such as wearable electronics and bendable displays. Precise and high-performance sensors readout chips are crucial for high quality flexible electronic products. In this work, the design of a CMOS readout circuit for an array of printed strain gauges is presented. The ultra-thin readout chip and the printed sensors are combined on a thin Benzocyclobutene/Polyimide (BCB/PI) substrate to form a Hybrid System-in-Foil (HySiF), which is used as an electronic skin for robotic applications. Each strain gauge utilizes a Wheatstone bridge circuit, where four Aerosol Jet® printed meander-shaped resistors form a full-bridge topology. The readout chip amplifies the output voltage difference (about 5 mV full-scale swing) of the strain gauge. One challenge during the sensor interface circuit design is to compensate for the relatively large dc offset (about 30 mV at 1 mA) in the bridge output voltage so that the amplified signal span matches the input range of an analog-to-digital converter (ADC). The circuit design uses the 0. 5 µm mixed-signal GATEFORESTTM technology. In order to achieve the mechanical flexibility, the chip fabrication is based on either back thinned wafers or the ChipFilmTM technology, which enables the manufacturing of silicon chips with a thickness of about 20 µm. The implemented readout chip uses a supply of 5 V and includes a 5-bit digital-to-analog converter (DAC), a differential difference amplifier (DDA), and a 10-bit successive approximation register (SAR) ADC. The circuit is simulated across process, supply and temperature corners and the simulation results indicate excellent performance in terms of circuit stability and linearity.
Applications of SAR Interferometry in Earth and Environmental Science Research
Zhou, Xiaobing; Chang, Ni-Bin; Li, Shusun
2009-01-01
This paper provides a review of the progress in regard to the InSAR remote sensing technique and its applications in earth and environmental sciences, especially in the past decade. Basic principles, factors, limits, InSAR sensors, available software packages for the generation of InSAR interferograms were summarized to support future applications. Emphasis was placed on the applications of InSAR in seismology, volcanology, land subsidence/uplift, landslide, glaciology, hydrology, and forestry sciences. It ends with a discussion of future research directions. PMID:22573992
Forest Structure Retrieval From EcoSAR P-Band Single-Pass Interferometry
NASA Technical Reports Server (NTRS)
Osmanoglu, Batuhan; Rincon, Rafael; Lee, Seung Kuk; Fatoyinbo, Temilola; Bollian, Tobias
2017-01-01
EcoSAR is a single-pass (dual antenna) digital beamforming, P-band radar system that is designed for remote sensing of dense forest structure. Forest structure retrievals require the measurement related to the vertical dimension, for which several techniques have been developed over the years. These techniques use polarimetric and interferometric aspects of the SAR data, which can be collected using EcoSAR. In this paper we describe EcoSAR system in light of its interferometric capabilities and investigate forest structure retrieval techniques.
Severe Acute Respiratory Syndrome–associated Coronavirus Infection
Ip, Margaret; Ng, KC; Wu, Alan; Lee, Nelson; Rainer, Timothy H.; Joynt, Gavin M.; Sung, Joseph J. Y.; Tam, John S.
2003-01-01
Whether severe acute respiratory syndrome–associated coronavirus (SARS-CoV) infection can be asymptomatic is unclear. We examined the seroprevalence of SARS-CoV among 674 healthcare workers from a hospital in which a SARS outbreak had occurred. A total of 353 (52%) experienced mild self-limiting illnesses, and 321 (48%) were asymptomatic throughout the course of these observations. None of these healthcare workers had antibody to SARS CoV, indicating that subclinical or mild infection attributable to SARS CoV in adults is rare. PMID:14718090
Applications of SAR Interferometry in Earth and Environmental Science Research.
Zhou, Xiaobing; Chang, Ni-Bin; Li, Shusun
2009-01-01
This paper provides a review of the progress in regard to the InSAR remote sensing technique and its applications in earth and environmental sciences, especially in the past decade. Basic principles, factors, limits, InSAR sensors, available software packages for the generation of InSAR interferograms were summarized to support future applications. Emphasis was placed on the applications of InSAR in seismology, volcanology, land subsidence/uplift, landslide, glaciology, hydrology, and forestry sciences. It ends with a discussion of future research directions.
Shearlet-based edge detection: flame fronts and tidal flats
NASA Astrophysics Data System (ADS)
King, Emily J.; Reisenhofer, Rafael; Kiefer, Johannes; Lim, Wang-Q.; Li, Zhen; Heygster, Georg
2015-09-01
Shearlets are wavelet-like systems which are better suited for handling geometric features in multi-dimensional data than traditional wavelets. A novel method for edge and line detection which is in the spirit of phase congruency but is based on a complex shearlet transform will be presented. This approach to detection yields an approximate tangent direction of detected discontinuities as a byproduct of the computation, which then yields local curvature estimates. Two applications of the edge detection method will be discussed. First, the tracking and classification of flame fronts is a critical component of research in technical thermodynamics. Quite often, the flame fronts are transient or weak and the images are noisy. The standard methods used in the field for the detection of flame fronts do not handle such data well. Fortunately, using the shearlet-based edge measure yields good results as well as an accurate approximation of local curvature. Furthermore, a modification of the method will yield line detection, which is important for certain imaging modalities. Second, the Wadden tidal flats are a biodiverse region along the North Sea coast. One approach to surveying the delicate region and tracking the topographical changes is to use pre-existing Synthetic Aperture Radar (SAR) images. Unfortunately, SAR data suffers from multiplicative noise as well as sensitivity to environmental factors. The first large-scale mapping project of that type showed good results but only with a tremendous amount of manual interaction because there are many edges in the data which are not boundaries of the tidal flats but are edges of features like fields or islands. Preliminary results will be presented.
Investigation of the Capability of Compact Polarimetric SAR Interferometry to Estimate Forest Height
NASA Astrophysics Data System (ADS)
Zhang, Hong; Xie, Lei; Wang, Chao; Chen, Jiehong
2013-08-01
The main objective of this paper is to investigate the capability of compact Polarimetric SAR Interferometry (C-PolInSAR) on forest height estimation. For this, the pseudo fully polarimetric interferomteric (F-PolInSAR) covariance matrix is firstly reconstructed, then the three- stage inversion algorithm, hybrid algorithm, Music and Capon algorithm are applied to both C-PolInSAR covariance matrix and pseudo F-PolInSAR covariance matrix. The availability of forest height estimation is demonstrated using L-band data generated by simulator PolSARProSim and X-band airborne data acquired by East China Research Institute of Electronic Engineering, China Electronics Technology Group Corporation.
Advanced Antenna Design for NASA's EcoSAR Instrument
NASA Technical Reports Server (NTRS)
Du Toit, Cornelis F.; Deshpande, Manohar; Rincon, Rafael F.
2016-01-01
Advanced antenna arrays were designed for NASA's EcoSAR airborne radar instrument. EcoSAR is a beamforming synthetic aperture radar instrument designed to make polarimetric and "single pass" interferometric measurements of Earth surface parameters. EcoSAR's operational requirements of a 435MHz center frequency with up to 200MHz bandwidth, dual polarization, high cross-polarization isolation (> 30 dB), +/- 45deg beam scan range and antenna form-factor constraints imposed stringent requirements on the antenna design. The EcoSAR project successfully developed, characterized, and tested two array antennas in an anechoic chamber. EcoSAR's first airborne campaign conducted in the spring of 2014 generated rich data sets of scientific and engineering value, demonstrating the successful operation of the antennas.
Real-Time Reverse Transcription–Polymerase Chain Reaction Assay for SARS-associated Coronavirus
Emery, Shannon L.; Bowen, Michael D.; Newton, Bruce R.; Winchell, Jonas M.; Meyer, Richard F.; Tong, Suxiang; Cook, Byron T.; Holloway, Brian P.; McCaustland, Karen A.; Rota, Paul A.; Bankamp, Bettina; Lowe, Luis E.; Ksiazek, Tom G.; Bellini, William J.; Anderson, Larry J.
2004-01-01
A real-time reverse transcription–polymerase chain reaction (RT-PCR) assay was developed to rapidly detect the severe acute respiratory syndrome–associated coronavirus (SARS-CoV). The assay, based on multiple primer and probe sets located in different regions of the SARS-CoV genome, could discriminate SARS-CoV from other human and animal coronaviruses with a potential detection limit of <10 genomic copies per reaction. The real-time RT-PCR assay was more sensitive than a conventional RT-PCR assay or culture isolation and proved suitable to detect SARS-CoV in clinical specimens. Application of this assay will aid in diagnosing SARS-CoV infection. PMID:15030703
Leivonen, Susanna; Voutilainen, Arja; Hinkka-Yli-Salomäki, Susanna; Timonen-Soivio, Laura; Chudal, Roshan; Gissler, Mika; Huttunen, Jukka; Sourander, Andre
2014-09-01
The aim of this study was to describe the characteristics and incidence rates of diagnosed tic disorders in the Finnish Hospital Discharge Register, including changing incidence rates between 1991 and 2010. We also aimed to validate the diagnoses of Tourette's syndrome recorded in the register. Children born between January 1, 1991 and December 31, 2010, who were diagnosed with tic disorders, were identified from the Finnish Hospital Discharge Register (n = 3003). We studied the validity of the Tourette's syndrome diagnoses by reviewing the medical charts of 88 children born since 1997 and carrying out telephone interviews with 55 of their guardians. The incidence rates of all diagnosed tic disorders increased during the study period. A comorbid diagnosis of hyperkinetic disorder diagnosis was recorded in 28.2% of the children with Tourette's syndrome, and the validity of the register-based Tourette's syndrome diagnosis was approximately 95%. This is the first nationwide study to demonstrate the increasing incidence of all register-based tic disorder diagnoses. The validity of the Tourette's syndrome diagnoses in the Finnish Hospital Discharge Register was good, and the data provided are suitable for use in further register-based studies of tic disorders. ©2014 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.
Spaceborne SAR Imaging Algorithm for Coherence Optimized.
Qiu, Zhiwei; Yue, Jianping; Wang, Xueqin; Yue, Shun
2016-01-01
This paper proposes SAR imaging algorithm with largest coherence based on the existing SAR imaging algorithm. The basic idea of SAR imaging algorithm in imaging processing is that output signal can have maximum signal-to-noise ratio (SNR) by using the optimal imaging parameters. Traditional imaging algorithm can acquire the best focusing effect, but would bring the decoherence phenomenon in subsequent interference process. Algorithm proposed in this paper is that SAR echo adopts consistent imaging parameters in focusing processing. Although the SNR of the output signal is reduced slightly, their coherence is ensured greatly, and finally the interferogram with high quality is obtained. In this paper, two scenes of Envisat ASAR data in Zhangbei are employed to conduct experiment for this algorithm. Compared with the interferogram from the traditional algorithm, the results show that this algorithm is more suitable for SAR interferometry (InSAR) research and application.
Spaceborne SAR Imaging Algorithm for Coherence Optimized
Qiu, Zhiwei; Yue, Jianping; Wang, Xueqin; Yue, Shun
2016-01-01
This paper proposes SAR imaging algorithm with largest coherence based on the existing SAR imaging algorithm. The basic idea of SAR imaging algorithm in imaging processing is that output signal can have maximum signal-to-noise ratio (SNR) by using the optimal imaging parameters. Traditional imaging algorithm can acquire the best focusing effect, but would bring the decoherence phenomenon in subsequent interference process. Algorithm proposed in this paper is that SAR echo adopts consistent imaging parameters in focusing processing. Although the SNR of the output signal is reduced slightly, their coherence is ensured greatly, and finally the interferogram with high quality is obtained. In this paper, two scenes of Envisat ASAR data in Zhangbei are employed to conduct experiment for this algorithm. Compared with the interferogram from the traditional algorithm, the results show that this algorithm is more suitable for SAR interferometry (InSAR) research and application. PMID:26871446
NASA Astrophysics Data System (ADS)
Costantini, Mario; Francioni, Elena; Trillo, Francesco; Minati, Federico; Margottini, Claudio; Spizzichino, Daniele; Trigila, Alessandro; Iadanza, Carla
2017-04-01
Archaeological sites and cultural heritage are considered as critical assets for the society, representing not only the history of region or a culture, but also contributing to create a common identity of people living in a certain region. In this view, it is becoming more and more urgent to preserve them from climate changes effect and in general from their degradation. These structures are usually just as precious as fragile: remote sensing technology can be useful to monitor these treasures. In this work, we will focus on ground deformation measurements obtained by satellite SAR interferometry and on the methodology adopted and implemented in order to use the results operatively for conservation policies in a Italian archaeological site. The analysis is based on the processing of COSMO-SkyMed Himage data by the e-GEOS proprietary Persistent Scatterer Pair (PSP) SAR interferometry technology. The PSP technique is a proven SAR interferometry technology characterized by the fact of exploiting in the processing only the relative properties between close points (pairs) in order to overcome atmospheric artefacts (which are one of the main problems of SAR interferometry). Validations analyses [Costantini et al. 2015] settled that this technique applied to COSMO-SkyMed Himage data is able to retrieve very dense (except of course on vegetated or cultivated areas) millimetric deformation measurements with sub-metric localization. Considering the limitations of all the interferometric techniques, in particular the fact that the measurement are along the line of sight (LOS) and the geometric distortions, in order to obtain the maximum information from interferometric analysis, both ascending and descending geometry have been used. The ascending analysis allows selecting measurements points over the top and, approximately, South-West part of the structures, while the descending one over the top and the South-East part of the structures. The interferometric techniques needs to use a stack of SAR images to separate the deformation phase contributions from other spurious components (atmospheric, orbital, etc.). Historical/reference analyses of the period 2011-2014 have been performed to obtain such deformations and to have a start point for the next updates. In fact, starting from the reference analyses the deformation monitoring has then continued with monthly updates of the PSP analysis with new COSMO-SkyMed acquisitions both in ascending and descending geometry. In addition to this traditional monitoring service, the satellite interferometry analysis has been realized over specific time frame that have been selected on the bases of some important events (damages to structures, collapses, works etc.) and the analysis have been correlated with additional site information as weather conditions, critical meteorological events, historical information of the site, etc. The objective is to find a nominal behaviour of the site in response to critical events and/or related to natural degradation of infrastructures in order to prevent damages and guide maintenance activities. The first results of this cross correlated analysis showed that some deformation phenomena are identifiable by SAR satellite interferometric analysis and it has also been possible to validate them on field through a direct survey.
Severe Acute Respiratory Syndrome (SARS) Prevention in Taiwan
ERIC Educational Resources Information Center
Liu, Hsueh-Erh
2004-01-01
Severe Acute Respiratory Syndrome (SARS) is a newly identified respiratory disease that threatened Taiwan between April 14 and July 5, 2003. Chang Gung University experienced various SARS-related episodes, such as the postponement of classes for 7 days, the reporting of probable SARS cases, and the isolation of students under Level A and B…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-19
...)(1), 625, 1844(c), 3105(c)(2), 3106(a), and 1818(s). SARs are exempt from Freedom of Information Act... of a SAR. Finally, information contained in SARs may be exempt from certain disclosure and other..., supervised banking organizations file SARs. Law enforcement agencies use the information submitted on the...
ERIC Educational Resources Information Center
Lau, Joseph T. F.; Yang, Xilin; Wong, Eric; Tsui, H. Y.
2006-01-01
The study investigated the general population's perceived infectivity of asymptomatic and recovered severe acute respiratory syndrome (SARS) patients and factors associated with avoidance and discriminatory attitudes, including demographic background, SARS-related perceptions and emotional response to the SARS epidemic. A population-based survey…
King, Chwan-Chuan; Chen, Cathy W. S.; Ho, Mei-Shang; Lee, Jen-Yu; Liu, Feng-Chi; Wu, Yi-Chun
2005-01-01
During the 2003 outbreak of severe acute respiratory syndrome (SARS) in Taiwan, >150,000 persons were quarantined, 24 of whom were later found to have laboratory-confirmed SARS-coronavirus (SARS-CoV) infection. Since no evidence exists that SARS-CoV is infective before the onset of symptoms and the quarantined persons were exposed but not symptomatic, we thought the quarantine's effectiveness should be investigated. Using the Taiwan quarantine data, we found that the onset-to-diagnosis time of previously quarantined confirmed case-patients was significantly shortened compared to that for those who had not been quarantined. Thus, quarantine for SARS in Taiwan screened potentially infective persons for swift diagnosis and hospitalization after onset, thereby indirectly reducing infections. Full-scale quarantine measures implemented on April 28 led to a significant improvement in onset-to-diagnosis time of all SARS patients, regardless of previous quarantine status. We discuss the temporal effects of quarantine measures and other interventions on detection and isolation as well as the potential usefulness of quarantine in faster identification of persons with SARS and in improving isolation measures. PMID:15752447
SARS Surveillance during Emergency Public Health Response, United States, March–July 2003
Brooks, John T.; Van Beneden, Chris; Parashar, Umesh D.; Griffin, Patricia M.; Anderson, Larry J.; Bellini, William J.; Benson, Robert F.; Erdman, Dean D.; Klimov, Alexander; Ksiazek, Thomas G.; Peret, Teresa C.T.; Talkington, Deborah F.; Thacker, W. Lanier; Tondella, Maria L.; Sampson, Jacquelyn S.; Hightower, Allen W.; Nordenberg, Dale F.; Plikaytis, Brian D.; Khan, Ali S.; Rosenstein, Nancy E.; Treadwell, Tracee A.; Whitney, Cynthia G.; Fiore, Anthony E.; Durant, Tonji M.; Perz, Joseph F.; Wasley, Annemarie; Feikin, Daniel; Herndon, Joy L.; Bower, William A.; Kilbourn, Barbara W.; Levy, Deborah A.; Coronado, Victor G.; Buffington, Joanna; Dykewicz, Clare A.; Khabbaz, Rima F.; Chamberland, Mary E.
2004-01-01
In response to the emergence of severe acute respiratory syndrome (SARS), the United States established national surveillance using a sensitive case definition incorporating clinical, epidemiologic, and laboratory criteria. Of 1,460 unexplained respiratory illnesses reported by state and local health departments to the Centers for Disease Control and Prevention from March 17 to July 30, 2003, a total of 398 (27%) met clinical and epidemiologic SARS case criteria. Of these, 72 (18%) were probable cases with radiographic evidence of pneumonia. Eight (2%) were laboratory-confirmed SARS-coronavirus (SARS-CoV) infections, 206 (52%) were SARS-CoV negative, and 184 (46%) had undetermined SARS-CoV status because of missing convalescent-phase serum specimens. Thirty-one percent (124/398) of case-patients were hospitalized; none died. Travel was the most common epidemiologic link (329/398, 83%), and mainland China was the affected area most commonly visited. One case of possible household transmission was reported, and no laboratory-confirmed infections occurred among healthcare workers. Successes and limitations of this emergency surveillance can guide preparations for future outbreaks of SARS or respiratory diseases of unknown etiology. PMID:15030681
Multisensor analysis of hydrologic features with emphasis on the Seasat SAR
NASA Technical Reports Server (NTRS)
Foster, J. L.; Hall, D. K.
1981-01-01
Synthetic aperture radar (SAR) imagery of the Wind River Range area in Wyoming is compared with visible and near-infrared imagery of the same area. Data from the Seasat L-Band SAR and an aircraft X-Band SAR are compared with Landsat Return Beam Vidicon (RBV) visible data and near-infrared aerial photography and topographic maps of the same area. It is noted that visible and near-infrared data provide more information than the SAR data when conditions are the most favorable. The SAR penetrates clouds and snow, however, and data can be acquired day or night. Drainage density detail is good on SAR imagery because individual streams show up well owing to riparian vegetation; this causes higher radar reflections which result from the 'rough' surface which vegetation creates. In the winter image, the X-Band radar data show high returns because of cracks on the lake ice surfaces. High returns can also be seen in the L-Band SAR imagery of the lakes due to ripples on the surface induced by wind. It is concluded that the use of multispectral data would optimize analysis of hydrologic features.
SARS-CoV Regulates Immune Function-Related Gene Expression in Human Monocytic Cells
Hu, Wanchung; Yen, Yu-Ting; Singh, Sher; Kao, Chuan-Liang
2012-01-01
Abstract Severe acute respiratory syndrome (SARS) is characterized by acute respiratory distress syndrome (ARDS) and pulmonary fibrosis, and monocytes/macrophages are the key players in the pathogenesis of SARS. In this study, we compared the transcriptional profiles of SARS coronavirus (SARS-CoV)-infected monocytic cells against that infected by coronavirus 229E (CoV-229E). Total RNA was extracted from infected DC-SIGN-transfected monocytes (THP-1-DC-SIGN) at 6 and 24 h after infection, and the gene expression was profiled in oligonucleotide-based microarrays. Analysis of immune-related gene expression profiles showed that at 24 h after SARS-CoV infection: (1) IFN-α/β-inducible and cathepsin/proteasome genes were downregulated; (2) hypoxia/hyperoxia-related genes were upregulated; and (3) TLR/TLR-signaling, cytokine/cytokine receptor-related, chemokine/chemokine receptor-related, lysosome-related, MHC/chaperon-related, and fibrosis-related genes were differentially regulated. These results elucidate that SARS-CoV infection regulates immune-related genes in monocytes/macrophages, which may be important to the pathogenesis of SARS. PMID:22876772
Analysis of Spatiotemporal Characteristics of Pandemic SARS Spread in Mainland China.
Cao, Chunxiang; Chen, Wei; Zheng, Sheng; Zhao, Jian; Wang, Jinfeng; Cao, Wuchun
2016-01-01
Severe acute respiratory syndrome (SARS) is one of the most severe emerging infectious diseases of the 21st century so far. SARS caused a pandemic that spread throughout mainland China for 7 months, infecting 5318 persons in 194 administrative regions. Using detailed mainland China epidemiological data, we study spatiotemporal aspects of this person-to-person contagious disease and simulate its spatiotemporal transmission dynamics via the Bayesian Maximum Entropy (BME) method. The BME reveals that SARS outbreaks show autocorrelation within certain spatial and temporal distances. We use BME to fit a theoretical covariance model that has a sine hole spatial component and exponential temporal component and obtain the weights of geographical and temporal autocorrelation factors. Using the covariance model, SARS dynamics were estimated and simulated under the most probable conditions. Our study suggests that SARS transmission varies in its epidemiological characteristics and SARS outbreak distributions exhibit palpable clusters on both spatial and temporal scales. In addition, the BME modelling demonstrates that SARS transmission features are affected by spatial heterogeneity, so we analyze potential causes. This may benefit epidemiological control of pandemic infectious diseases.
Pillaiyar, Thanigaimalai; Manickam, Manoj; Namasivayam, Vigneshwaran; Hayashi, Yoshio; Jung, Sang-Hun
2016-07-28
Severe acute respiratory syndrome (SARS) is caused by a newly emerged coronavirus that infected more than 8000 individuals and resulted in more than 800 (10-15%) fatalities in 2003. The causative agent of SARS has been identified as a novel human coronavirus (SARS-CoV), and its viral protease, SARS-CoV 3CL(pro), has been shown to be essential for replication and has hence been recognized as a potent drug target for SARS infection. Currently, there is no effective treatment for this epidemic despite the intensive research that has been undertaken since 2003 (over 3500 publications). This perspective focuses on the status of various efficacious anti-SARS-CoV 3CL(pro) chemotherapies discovered during the last 12 years (2003-2015) from all sources, including laboratory synthetic methods, natural products, and virtual screening. We describe here mainly peptidomimetic and small molecule inhibitors of SARS-CoV 3CL(pro). Attempts have been made to provide a complete description of the structural features and binding modes of these inhibitors under many conditions.
Analysis of Spatiotemporal Characteristics of Pandemic SARS Spread in Mainland China
Cao, Chunxiang; Zheng, Sheng; Zhao, Jian; Wang, Jinfeng; Cao, Wuchun
2016-01-01
Severe acute respiratory syndrome (SARS) is one of the most severe emerging infectious diseases of the 21st century so far. SARS caused a pandemic that spread throughout mainland China for 7 months, infecting 5318 persons in 194 administrative regions. Using detailed mainland China epidemiological data, we study spatiotemporal aspects of this person-to-person contagious disease and simulate its spatiotemporal transmission dynamics via the Bayesian Maximum Entropy (BME) method. The BME reveals that SARS outbreaks show autocorrelation within certain spatial and temporal distances. We use BME to fit a theoretical covariance model that has a sine hole spatial component and exponential temporal component and obtain the weights of geographical and temporal autocorrelation factors. Using the covariance model, SARS dynamics were estimated and simulated under the most probable conditions. Our study suggests that SARS transmission varies in its epidemiological characteristics and SARS outbreak distributions exhibit palpable clusters on both spatial and temporal scales. In addition, the BME modelling demonstrates that SARS transmission features are affected by spatial heterogeneity, so we analyze potential causes. This may benefit epidemiological control of pandemic infectious diseases. PMID:27597972
SARS-CoV regulates immune function-related gene expression in human monocytic cells.
Hu, Wanchung; Yen, Yu-Ting; Singh, Sher; Kao, Chuan-Liang; Wu-Hsieh, Betty A
2012-08-01
Severe acute respiratory syndrome (SARS) is characterized by acute respiratory distress syndrome (ARDS) and pulmonary fibrosis, and monocytes/macrophages are the key players in the pathogenesis of SARS. In this study, we compared the transcriptional profiles of SARS coronavirus (SARS-CoV)-infected monocytic cells against that infected by coronavirus 229E (CoV-229E). Total RNA was extracted from infected DC-SIGN-transfected monocytes (THP-1-DC-SIGN) at 6 and 24 h after infection, and the gene expression was profiled in oligonucleotide-based microarrays. Analysis of immune-related gene expression profiles showed that at 24 h after SARS-CoV infection: (1) IFN-α/β-inducible and cathepsin/proteasome genes were downregulated; (2) hypoxia/hyperoxia-related genes were upregulated; and (3) TLR/TLR-signaling, cytokine/cytokine receptor-related, chemokine/chemokine receptor-related, lysosome-related, MHC/chaperon-related, and fibrosis-related genes were differentially regulated. These results elucidate that SARS-CoV infection regulates immune-related genes in monocytes/macrophages, which may be important to the pathogenesis of SARS.
A discussion on the use of X-band SAR images in marine applications
NASA Astrophysics Data System (ADS)
Schiavulli, D.; Sorrentino, A.; Migliaccio, M.
2012-10-01
The Synthetic Aperture Radar (SAR) is able to generate images of the sea surface that can be exploited to extract geophysical information of environmental interest. In order to enhance the operational use of these data in the marine applications the revisit time is to be improved. This goal can be achieved by using SAR virtual or real constellations and/or exploiting new antenna technologies that allow huge swath and fine resolution. Within this framework, the presence of the Italian and German X-band SAR constellations is of special interest while the new SAR technologies are not nowadays operated. Although SAR images are considered to be independent of weather conditions, this is only partially true at higher frequencies, e.g. X-band. In fact, observations can present signature corresponding to high intensity precipitating clouds, i.e. rain cells. Further, ScanSAR images may be characterized by the presence of processing artifacts, called scalloping, that corrupt image interpretation. In this paper we review these key facts that are at the basis of an effective use of X-band SAR images for marine applications.
New Ground Truth Capability from InSAR Time Series Analysis
DOE Office of Scientific and Technical Information (OSTI.GOV)
Buckley, S; Vincent, P; Yang, D
2005-07-13
We demonstrate that next-generation interferometric synthetic aperture radar (InSAR) processing techniques applied to existing data provide rich InSAR ground truth content for exploitation in seismic source identification. InSAR time series analyses utilize tens of interferograms and can be implemented in different ways. In one such approach, conventional InSAR displacement maps are inverted in a final post-processing step. Alternatively, computationally intensive data reduction can be performed with specialized InSAR processing algorithms. The typical final result of these approaches is a synthesized set of cumulative displacement maps. Examples from our recent work demonstrate that these InSAR processing techniques can provide appealing newmore » ground truth capabilities. We construct movies showing the areal and temporal evolution of deformation associated with previous nuclear tests. In other analyses, we extract time histories of centimeter-scale surface displacement associated with tunneling. The potential exists to identify millimeter per year surface movements when sufficient data exists for InSAR techniques to isolate and remove phase signatures associated with digital elevation model errors and the atmosphere.« less
NASA Astrophysics Data System (ADS)
Kayastha, Shilva; Kunimoto, Ryo; Horvath, Dragos; Varnek, Alexandre; Bajorath, Jürgen
2017-11-01
The analysis of structure-activity relationships (SARs) becomes rather challenging when large and heterogeneous compound data sets are studied. In such cases, many different compounds and their activities need to be compared, which quickly goes beyond the capacity of subjective assessments. For a comprehensive large-scale exploration of SARs, computational analysis and visualization methods are required. Herein, we introduce a two-layered SAR visualization scheme specifically designed for increasingly large compound data sets. The approach combines a new compound pair-based variant of generative topographic mapping (GTM), a machine learning approach for nonlinear mapping, with chemical space networks (CSNs). The GTM component provides a global view of the activity landscapes of large compound data sets, in which informative local SAR environments are identified, augmented by a numerical SAR scoring scheme. Prioritized local SAR regions are then projected into CSNs that resolve these regions at the level of individual compounds and their relationships. Analysis of CSNs makes it possible to distinguish between regions having different SAR characteristics and select compound subsets that are rich in SAR information.
2004-03-10
L to R; NASA Dryden Mission Manager Walter Klein (in tan flight suit), JPL AirSAR Scientist Tim Miller, and Mission Manager David Bushman briefing press in Santiago, Chile, for NASA's AirSAR 2004 mission. AirSAR 2004 is a three-week expedition by an international team of scientists that uses an all-weather imaging tool, called the Airborne Synthetic Aperture Radar (AirSAR) which is located onboard NASA's DC-8 airborne laboratory. Scientists from many parts of the world including NASA's Jet Propulsion Laboratory are combining ground research done in several areas in Central and South America with NASA's AirSAR technology to improve and expand on the quality of research they are able to conduct. In South America and Antarctica, AirSAR collected imagery and data to help determine the contribution of Southern Hemisphere glaciers to sea level rise due to climate change. In Patagonia, researchers found this contribution had more than doubled from 1995 to 2000, compared to the previous 25 years. AirSAR data will make it possible to determine whether that trend is continuing or accelerating. AirSAR will also provide reliable information on ice shelf thickness to measure the contribution of the glaciers to sea level.
Late summer sea ice segmentation with multi-polarisation SAR features in C- and X-band
NASA Astrophysics Data System (ADS)
Fors, A. S.; Brekke, C.; Doulgeris, A. P.; Eltoft, T.; Renner, A. H. H.; Gerland, S.
2015-09-01
In this study we investigate the potential of sea ice segmentation by C- and X-band multi-polarisation synthetic aperture radar (SAR) features during late summer. Five high-resolution satellite SAR scenes were recorded in the Fram Strait covering iceberg-fast first-year and old sea ice during a week with air temperatures varying around zero degrees Celsius. In situ data consisting of sea ice thickness, surface roughness and aerial photographs were collected during a helicopter flight at the site. Six polarimetric SAR features were extracted for each of the scenes. The ability of the individual SAR features to discriminate between sea ice types and their temporally consistency were examined. All SAR features were found to add value to sea ice type discrimination. Relative kurtosis, geometric brightness, cross-polarisation ratio and co-polarisation correlation angle were found to be temporally consistent in the investigated period, while co-polarisation ratio and co-polarisation correlation magnitude were found to be temporally inconsistent. An automatic feature-based segmentation algorithm was tested both for a full SAR feature set, and for a reduced SAR feature set limited to temporally consistent features. In general, the algorithm produces a good late summer sea ice segmentation. Excluding temporally inconsistent SAR features improved the segmentation at air temperatures above zero degrees Celcius.
How change of public transportation usage reveals fear of the SARS virus in a city.
Wang, Kuo-Ying
2014-01-01
The outbreaks of the severe acute respiratory syndrome (SARS) epidemic in 2003 resulted in unprecedented impacts on people's daily life. One of the most significant impacts to people is the fear of contacting the SARS virus while engaging daily routine activity. Here we use data from daily underground ridership in Taipei City and daily reported new SARS cases in Taiwan to model the dynamics of the public fear of the SARS virus during the wax and wane of the SARS period. We found that for each reported new SARS case there is an immediate loss of about 1200 underground ridership (the fresh fear). These daily loss rates dissipate to the following days with an e-folding time of about 28 days, reflecting the public perception on the risk of contacting SARS virus when traveling with the underground system (the residual fear). About 50% of daily ridership was lost during the peak of the 2003 SARS period, compared with the loss of 80% daily ridership during the closure of the underground system after Typhoon Nari, the loss of 50-70% ridership due to the closure of the governmental offices and schools during typhoon periods, and the loss of 60% daily ridership during Chinese New Year holidays.
Monoterpenes Support Systemic Acquired Resistance within and between Plants
Ghirardo, Andrea; Knappe, Claudia; Koch, Kerstin; Dey, Sanjukta; Parker, Jane E.
2017-01-01
This study investigates the role of volatile organic compounds in systemic acquired resistance (SAR), a salicylic acid (SA)-associated, broad-spectrum immune response in systemic, healthy tissues of locally infected plants. Gas chromatography coupled to mass spectrometry analyses of SAR-related emissions of wild-type and non-SAR-signal-producing mutant plants associated SAR with monoterpene emissions. Headspace exposure of Arabidopsis thaliana to a mixture of the bicyclic monoterpenes α-pinene and β-pinene induced defense, accumulation of reactive oxygen species, and expression of SA- and SAR-related genes, including the SAR regulatory AZELAIC ACID INDUCED1 (AZI1) gene and three of its paralogs. Pinene-induced resistance was dependent on SA biosynthesis and signaling and on AZI1. Arabidopsis geranylgeranyl reductase1 mutants with reduced monoterpene biosynthesis were SAR-defective but mounted normal local resistance and methyl salicylate-induced defense responses, suggesting that monoterpenes act in parallel with SA. The volatile emissions from SAR signal-emitting plants induced defense in neighboring plants, and this was associated with the presence of α-pinene, β-pinene, and camphene in the emissions of the “sender” plants. Our data suggest that monoterpenes, particularly pinenes, promote SAR, acting through ROS and AZI1, and likely function as infochemicals in plant-to-plant signaling, thus allowing defense signal propagation between neighboring plants. PMID:28536145
SAR11 bacteria linked to ocean anoxia and nitrogen loss
Tsementzi, Despina; Wu, Jieying; Deutsch, Samuel; Nath, Sangeeta; Rodriguez-R, Luis M; Burns, Andrew S.; Ranjan, Piyush; Sarode, Neha; Malmstrom, Rex R.; Padilla, Cory C.; Stone, Benjamin K.; Bristow, Laura A.; Larsen, Morten; Glass, Jennifer B.; Thamdrup, Bo; Woyke, Tanja; Konstantinidis, Konstantinos T.; Stewart, Frank J.
2016-01-01
Summary Bacteria of the SAR11 clade constitute up to one half of all microbial cells in the oxygen-rich surface ocean. DNA sequences from SAR11 are also abundant in oxygen minimum zones (OMZs) where oxygen falls below detection and anaerobic microbes play important roles in converting bioavailable nitrogen to N2 gas. Evidence for anaerobic metabolism in SAR11 has not yet been observed, and the question of how these bacteria contribute to OMZ biogeochemical cycling is unanswered. Here, we identify the metabolic basis for SAR11 activity in anoxic ocean waters. Genomic analysis of single cells from the world’s largest OMZ revealed diverse and previously uncharacterized SAR11 lineages that peak in abundance at anoxic depths, but are largely undetectable in oxygen-rich ocean regions. OMZ SAR11 contain adaptations to low oxygen, including genes for respiratory nitrate reductases (Nar). SAR11 nar genes were experimentally verified to encode proteins catalyzing the nitrite-producing first step of denitrification and constituted ~40% of all OMZ nar transcripts, with transcription peaking in the zone of maximum nitrate reduction rates. These results redefine the ecological niche of Earth’s most abundant organismal group and suggest an important contribution of SAR11 to nitrite production in OMZs, and thus to pathways of ocean nitrogen loss. PMID:27487207
How Change of Public Transportation Usage Reveals Fear of the SARS Virus in a City
Wang, Kuo-Ying
2014-01-01
The outbreaks of the severe acute respiratory syndrome (SARS) epidemic in 2003 resulted in unprecedented impacts on people's daily life. One of the most significant impacts to people is the fear of contacting the SARS virus while engaging daily routine activity. Here we use data from daily underground ridership in Taipei City and daily reported new SARS cases in Taiwan to model the dynamics of the public fear of the SARS virus during the wax and wane of the SARS period. We found that for each reported new SARS case there is an immediate loss of about 1200 underground ridership (the fresh fear). These daily loss rates dissipate to the following days with an e-folding time of about 28 days, reflecting the public perception on the risk of contacting SARS virus when traveling with the underground system (the residual fear). About 50% of daily ridership was lost during the peak of the 2003 SARS period, compared with the loss of 80% daily ridership during the closure of the underground system after Typhoon Nari, the loss of 50–70% ridership due to the closure of the governmental offices and schools during typhoon periods, and the loss of 60% daily ridership during Chinese New Year holidays. PMID:24647278
de Zwart, Onno; Veldhuijzen, Irene K; Elam, Gillian; Aro, Arja R; Abraham, Thomas; Bishop, George D; Voeten, Hélène A C M; Richardus, Jan Hendrik; Brug, Johannes
2009-01-01
To study the levels of perceived threat, perceived severity, perceived vulnerability, response efficacy, and self-efficacy for severe acute respiratory syndrome (SARS) and eight other diseases in five European and three Asian countries. A computer-assisted phone survey was conducted among 3,436 respondents. The questionnaire focused on perceived threat, vulnerability, severity, response efficacy, and self-efficacy related to SARS and eight other diseases. Perceived threat of SARS in case of an outbreak in the country was higher than that of other diseases. Perceived vulnerability of SARS was at an intermediate level and perceived severity was high compared to other diseases. Perceived threat for SARS varied between countries in Europe and Asia with a higher perceived severity of SARS in Europe and a higher perceived vulnerability in Asia. Response efficacy and self-efficacy for SARS were higher in Asia compared to Europe. In multiple linear regression analyses, country was strongly associated with perceived threat. The relatively high perceived threat for SARS indicates that it is seen as a public health risk and offers a basis for communication in case of an outbreak. The strong association between perceived threat and country and different regional patterns require further research.
Phakthanakanok, Krongsakda; Ratanakhanokchai, Khanok; Kyu, Khin Lay; Sompornpisut, Pornthep; Watts, Aaron; Pinitglang, Surapong
2009-01-01
Background SARS coronavirus main proteinase (SARS CoVMpro) is an important enzyme for the replication of Severe Acute Respiratory Syndrome virus. The active site region of SARS CoVMpro is divided into 8 subsites. Understanding the binding mode of SARS CoVMpro with a specific substrate is useful and contributes to structural-based drug design. The purpose of this research is to investigate the binding mode between the SARS CoVMpro and two octapeptides, especially in the region of the S3 subsite, through a molecular docking and molecular dynamics (MD) simulation approach. Results The one turn α-helix chain (residues 47–54) of the SARS CoVMpro was directly involved in the induced-fit model of the enzyme-substrate complex. The S3 subsite of the enzyme had a negatively charged region due to the presence of Glu47. During MD simulations, Glu47 of the enzyme was shown to play a key role in electrostatic bonding with the P3Lys of the octapeptide. Conclusion MD simulations were carried out on the SARS CoVMpro-octapeptide complex. The hypothesis proposed that Glu47 of SARS CoVMpro is an important residue in the S3 subsite and is involved in binding with P3Lys of the octapeptide. PMID:19208150
Web-GIS-based SARS epidemic situation visualization
NASA Astrophysics Data System (ADS)
Lu, Xiaolin
2004-03-01
In order to research, perform statistical analysis and broadcast the information of SARS epidemic situation according to the relevant spatial position, this paper proposed a unified global visualization information platform for SARS epidemic situation based on Web-GIS and scientific virtualization technology. To setup the unified global visual information platform, the architecture of Web-GIS based interoperable information system is adopted to enable public report SARS virus information to health cure center visually by using the web visualization technology. A GIS java applet is used to visualize the relationship between spatial graphical data and virus distribution, and other web based graphics figures such as curves, bars, maps and multi-dimensional figures are used to visualize the relationship between SARS virus tendency with time, patient number or locations. The platform is designed to display the SARS information in real time, simulate visually for real epidemic situation and offer an analyzing tools for health department and the policy-making government department to support the decision-making for preventing against the SARS epidemic virus. It could be used to analyze the virus condition through visualized graphics interface, isolate the areas of virus source, and control the virus condition within shortest time. It could be applied to the visualization field of SARS preventing systems for SARS information broadcasting, data management, statistical analysis, and decision supporting.
NASA Technical Reports Server (NTRS)
Chapman, Bruce; Celi, Jorge; Hamilton, Steve; McDonald, Kyle
2013-01-01
UAVSAR, NASA's airborne Synthetic Aperture Radar (SAR), conducted an extended observational campaign in Central and South America in March 2013, primarily related to volcanic deformations along the Andean Mountain Range but also including a large number of flights studying other scientific phenomena. During this campaign, the L-Band SAR collected data over the Napo River in Ecuador. The objectives of this experiment were to acquire polarimetric and interferometric L-Band SAR data over an inundated tropical forest in Ecuador simultaneously with on-the-ground field work ascertaining the extent of inundation, and to then derive from this data a quantitative estimate for the error in the SAR-derived inundation extent. In this paper, we will first describe the processing and preliminary analysis of the SAR data. The polarimetric SAR data will be classified by land cover and inundation state. The interferometric SAR data will be used to identify those areas where change in inundation extent occurred, and to measure the change in water level between two observations separated by a week. Second, we will describe the collection of the field estimates of inundation, and have preliminary comparisons of inundation extent measured in the field field versus that estimated from the SAR data.
Segmentation of Polarimetric SAR Images Usig Wavelet Transformation and Texture Features
NASA Astrophysics Data System (ADS)
Rezaeian, A.; Homayouni, S.; Safari, A.
2015-12-01
Polarimetric Synthetic Aperture Radar (PolSAR) sensors can collect useful observations from earth's surfaces and phenomena for various remote sensing applications, such as land cover mapping, change and target detection. These data can be acquired without the limitations of weather conditions, sun illumination and dust particles. As result, SAR images, and in particular Polarimetric SAR (PolSAR) are powerful tools for various environmental applications. Unlike the optical images, SAR images suffer from the unavoidable speckle, which causes the segmentation of this data difficult. In this paper, we use the wavelet transformation for segmentation of PolSAR images. Our proposed method is based on the multi-resolution analysis of texture features is based on wavelet transformation. Here, we use the information of gray level value and the information of texture. First, we produce coherency or covariance matrices and then generate span image from them. In the next step of proposed method is texture feature extraction from sub-bands is generated from discrete wavelet transform (DWT). Finally, PolSAR image are segmented using clustering methods as fuzzy c-means (FCM) and k-means clustering. We have applied the proposed methodology to full polarimetric SAR images acquired by the Uninhabited Aerial Vehicle Synthetic Aperture Radar (UAVSAR) L-band system, during July, in 2012 over an agricultural area in Winnipeg, Canada.
Li, D; Wu, N; Yao, H; Bader, A; Brockmeyer, Norbert H; Altmeyer, P
2005-03-29
Severe acute respiratory syndrome (SARS) is a novel infectious disease which is characterized by an overaggressive immune response. Chemokines are important inflammatory mediators and regulate disease due to viral infection. In previous study, we found that SARS-CoV has the ability to replicate in mononuclear cells. In present work, we sought to characterize the replication of SARS-CoV at the presence of RANTES in THP-1 cells. To determine whether RANTES play an role in the process of SARS, THP-1 cells were incubated with heat-inactivated SARS-CoV and ELISA was used to test RANTES levels in the supernatants; Then the effect of dexamethasone on the induced secretion was evaluated. Real-time PCR was used to investigate the effort of RANTES on the replication of SARS-CoV in vitro. Macrophages, induced by THP-1 cells, were used as cell model. Inactive SARS-CoV could induce THP-1 cells secret RANTES and this increase effect could not be suppressed by DXM. RANTES itself could inhibit the replication of SARS-CoV in THP-1 cells when it was added into the culture before or at the same time with the virus; No inhibition effect was shown when RANTES were added into the culture after SARS-CoV infected the cells.
Guérin, Bastien; Setsompop, Kawin; Ye, Huihui; Poser, Benedikt A; Stenger, Andrew V; Wald, Lawrence L
2015-05-01
To design parallel transmit (pTx) simultaneous multislice (SMS) spokes pulses with explicit control for peak power and local and global specific absorption rate (SAR). We design SMS pTx least-squares and magnitude least squares spokes pulses while constraining local SAR using the virtual observation points (VOPs) compression of SAR matrices. We evaluate our approach in simulations of a head (7T) and a body (3T) coil with eight channels arranged in two z-rows. For many of our simulations, control of average power by Tikhonov regularization of the SMS pTx spokes pulse design yielded pulses that violated hardware and SAR safety limits. On the other hand, control of peak power alone yielded pulses that violated local SAR limits. Pulses optimized with control of both local SAR and peak power satisfied all constraints and therefore had the best excitation performance under limited power and SAR constraints. These results extend our previous results for single slice pTx excitations but are more pronounced because of the large power demands and SAR of SMS pulses. Explicit control of local SAR and peak power is required to generate optimal SMS pTx excitations satisfying both the system's hardware limits and regulatory safety limits. © 2014 Wiley Periodicals, Inc.
Neufeld, Esra; Gosselin, Marie-Christine; Murbach, Manuel; Christ, Andreas; Cabot, Eugenia; Kuster, Niels
2011-08-07
Multi-transmit coils are increasingly being employed in high-field magnetic resonance imaging, along with a growing interest in multi-transmit body coils. However, they can lead to an increase in whole-body and local specific absorption rate (SAR) compared to conventional body coils excited in circular polarization for the same total incident input power. In this study, the maximum increase of SAR for three significantly different human anatomies is investigated for a large 3 T (128 MHz) multi-transmit body coil using numerical simulations and a (generalized) eigenvalue-based approach. The results demonstrate that the increase of SAR strongly depends on the anatomy. For the three models and normalization to the sum of the rung currents squared, the whole-body averaged SAR increases by up to a factor of 1.6 compared to conventional excitation and the peak spatial SAR (averaged over any 10 cm(3) of tissue) by up to 13.4. For some locations the local averaged SAR goes up as much as 800 times (130 when looking only at regions where it is above 1% of the peak spatial SAR). The ratio of the peak spatial SAR to the whole-body SAR increases by a factor of up to 47 and can reach values above 800. Due to the potentially much larger power deposition, additional, preferably patient-specific, considerations are necessary to avoid injuries by such systems.
Calibration and Validation of Airborne InSAR Geometric Model
NASA Astrophysics Data System (ADS)
Chunming, Han; huadong, Guo; Xijuan, Yue; Changyong, Dou; Mingming, Song; Yanbing, Zhang
2014-03-01
The image registration or geo-coding is a very important step for many applications of airborne interferometric Synthetic Aperture Radar (InSAR), especially for those involving Digital Surface Model (DSM) generation, which requires an accurate knowledge of the geometry of the InSAR system. While the trajectory and attitude instabilities of the aircraft introduce severe distortions in three dimensional (3-D) geometric model. The 3-D geometrical model of an airborne SAR image depends on the SAR processor itself. Working at squinted model, i.e., with an offset angle (squint angle) of the radar beam from broadside direction, the aircraft motion instabilities may produce distortions in airborne InSAR geometric relationship, which, if not properly being compensated for during SAR imaging, may damage the image registration. The determination of locations of the SAR image depends on the irradiated topography and the exact knowledge of all signal delays: range delay and chirp delay (being adjusted by the radar operator) and internal delays which are unknown a priori. Hence, in order to obtain reliable results, these parameters must be properly calibrated. An Airborne InSAR mapping system has been developed by the Institute of Remote Sensing and Digital Earth (RADI), Chinese Academy of Sciences (CAS) to acquire three-dimensional geo-spatial data with high resolution and accuracy. To test the performance of the InSAR system, the Validation/Calibration (Val/Cal) campaign has carried out in Sichun province, south-west China, whose results will be reported in this paper.
Dynamics of Kilauea's Magmatic System Imaged Using a Joint Analysis of Geodetic and Seismic Data
NASA Astrophysics Data System (ADS)
Wauthier, C.; Roman, D. C.; Poland, M. P.; Fukushima, Y.; Hooper, A. J.
2012-12-01
Nowadays, Interferometric Synthetic Aperture Radar (InSAR) is commonly used to study a wide range of active volcanic areas. InSAR provides high-spatial-resolution measurements of surface deformation with centimeter-scale accuracy. At Kilauea Volcano, Hawai'i, InSAR shows complex processes that are not well constrained by GPS data (which have relatively poor spatial resolution). However, GPS data have higher temporal resolution than InSAR data. Both datasets are thus complementary. To overcome some of the limitations of conventional InSAR, which are mainly induced by temporal decorrelation, topographic, orbital and atmospheric delays, a Multi-Temporal InSAR (MT-InSAR) approach can be used. MT-InSAR techniques involve the processing of multiple SAR acquisitions over the same area. Two classes of MT-InSAR algorithms are defined: the persistent scatterers (PS) and small baseline (SBAS) methods. Each method is designed for a specific type of scattering mechanism. A PS pixel is a pixel in which a single scatterer dominates, while the contributions from other scatterers are negligible. A SBAS pixel is a pixel that includes distributed scatterers, which have a phase with little decorrelation over short time periods. Here, we apply the "StaMPS" ("Stanford Method for Permanent Scatterers") technique, which incorporates both a PS and SBAS approach, on ENVISAT and ALOS datasets acquired from 2003 to 2010 at Kilauea. In particular, we focus our InSAR analysis on the time period before the June 2007 "Father's Day" dike intrusion and eruption, and also incorporate seismic and GPS data in our models. Our goal is to identify any precursors to the Father's Day event within Kilauea's summit magma system, east rift zone, and/or southwest rift zone.
Xiong, P; Zeng, X; Song, M S; Jia, S W; Zhong, M H; Xiao, L L; Lan, W; Cai, C; Wu, X W; Gong, F L; Wang, W
2008-02-01
Severe acute respiratory syndrome (SARS), caused by infection with a novel coronavirus (SARS-CoV), was the first major novel infectious disease at the beginning of the 21st century, with China especially affected. SARS was characterized by high infectivity, morbidity and mortality, and the confined pattern of the disease spreading among the countries of South-East and East Asia suggested the existence of susceptible factor(s) in these populations. Studies in the populations of Hong Kong and Taiwan showed an association of human leucocyte antigen (HLA) polymorphisms with the development and/or severity of SARS, respectively. The aim of the present study was to define the genotypic patterns of HLA-A, -B and -DRB1 loci in SARS patients and a co-resident population of Guangdong province, southern China, where the first SARS case was reported. The samples comprised 95 cases of recovered SARS patients and 403 unrelated healthy controls. HLA -A, -B and -DRB1 alleles were genotyped using polymerase chain reaction with sequence-specific primers. The severity of the disease was assessed according to the history of lung infiltration, usage of assisted ventilation and occurrence of lymphocytopenia. Although the allelic frequencies of A23, A34, B60, DRB1*12 in the SARS group were slightly higher, and A33, -B58 and -B61 were lower than in the controls, no statistical significance was found when the Pc value was considered. Similarly, no association of HLA alleles with the severity of the disease was detected. Thus, variations in the major histocompatibility complex are unlikely to have contributed significantly to either the susceptibility or the severity of SARS in the population of Guangdong.