Science.gov

Sample records for apres chirurgie bariatrique

  1. Cinétique de la troponine Ic et valeurs seuils pour le diagnostic d'infarctus du myocarde après chirurgie cardiaque sous circulation extracorporelle

    PubMed Central

    Kallel, Samy; Jarraya, Anwar; Ellouze, Maged; Frikha, Imed; Karoui, Abbdelhamid

    2012-01-01

    Introduction L'objectif de ce travail était d’étudier la cinétique de la Troponine Ic (TnIc) après chirurgie cardiaque sous circulation extracorporelle (CEC) et établir des valeurs seuils de TnIc pour le diagnostic d'infarctus du myocarde (IDM) post opératoire. Il s'agissait d'une étude prospective type cohorte observationnelle. Méthodes Nous avons inclus 37 patients âgés de plus de 18 ans proposés pour chirurgie valvulaire ou pontage aorto coronarien sous CEC. Nous avons suivi la cinétique de TnIc par des dosages immunoenzymatique sur mini-vidas® avant et après la CEC, à H4 et H12 postopératoire puis tous les jours les 4 premiers jours. Le cutoff pour le diagnostic d'IDM post opératoire a été défini comme la valeur moyenne de troponine + deux déviations standards des patients indemnes de complications cardiaques. Résultats Les valeurs de TnIc en préopératoire étaient toutes inférieures au seuil de détection de la méthode de dosage (<0,01µg/l). Les valeurs de TnIc augmentent en postopératoire immédiat pour atteindre un maximum à H4 puis diminuent progressivement pour se normaliser après 4 à 5 jours. Les valeurs seuils ont été déterminées pour H0, H4,H12, H24, H48, H72, H96 et ont été respectivement 1.36, 2.58, 3.1, 3.23, 2.13, 1.53, 1.17 pour la chirurgie coronaire et 3.75, 5.39, 4.22, 3.41, 1.65, 1.3 1.19 pour la chirurgie valvulaire. Conclusion La connaissance de la cinétique de TnIc lors de chirurgie cardiaque non compliquée et la fixation de valeur seuil ou Cutoff permet aux cliniciens de distinguer entre dommage myocardique secondaire à la chirurgie et IDM. PMID:23396754

  2. Epidémiologie et facteurs de risque des complications respiratoires majeures après chirurgie de l'aorte abdominale au CHU Ibn Sina, Maroc

    PubMed Central

    Awab, Almahdi; Elahmadi, Brahim; Lamkinsi, Tarik; El Moussaoui, Rachid; El Hijri, Ahmed; Azzouzi, Abderrahim; Alilou, Mustapha

    2013-01-01

    Introduction L'incidence des complications respiratoires postopératoires (CRPO) reste très diversement appréciées selon les critères diagnostiques retenues dans les différentes études, ce qui la fait varier de 5 à plus de 50%. Les CRPO majeurs après chirurgie de l'aorte abdominale sont responsables d'une grande morbi-mortalité pouvant aller jusqu’à 36%, d'une durée d'hospitalisation et d'un coût plus importants. Ainsi dans l'optique d'améliorer notre prise en charge périopératoire de la chirurgie de l'aorte, nous avons décidé de mener une étude pour dresser le profil épidémiologique et déterminer les facteurs de risque des complications respiratoires dans notre contexte Méthodes Il s'agit d'une étude de cohorte rétrospective du mois de Janvier 2007 au mois de décembre 2011 portant sur l'ensemble des patients opérés pour pathologie aortique au bloc opératoire central de l'hôpital Ibn Sina de Rabat, Maroc. Résultats Cent vingt cinq patients ont été inclus dans notre étude, 24 patients ont été opérés pour anévrysme de l'aorte abdominale et 101 patients pour lésion occlusive aortoiliaque. Dans notre série 22 malades soit 17,6% ont présenté une complication respiratoire majeure avec, une reventilation dans 4,8% des cas, une difficulté de sevrage de la ventilation artificielle dans 3,2% des cas, une pneumopathie dans 4% des cas, un syndrome de détresse respiratoire aigue (SDRA) dans 4% des cas et une nécessité de fibroaspiration bronchique dans 1,6% des cas. En analyse univariée: l’âge, la présence d'une BPCO avec dyspnée stade 3 ou 4, la présence d'une anomalie à l'EFR préopératoire, la présence d'un stade avancé (III ou IV) de LOAI et la reprise chirurgicale étaient statistiquement associés à la survenue d'une complication respiratoire postopératoire. En analyse multivariée, seule une anomalie à l'EFR en préopératoire constituait un facteur de risque indépendant de survenue d'une complication

  3. Pronostic visuel et évolution réfractive après chirurgie de la cataracte congénitale avec implantation primaire: étude d'une série de 108 cas

    PubMed Central

    Hafidi, Zouheir; Ibrahimy, Wafaa; Ahid, Samir; Handor, Hanan; Ouafae Cherkaoui, Lalla; Bencherif, Zahid; Laghmari, Mina; Ouazzanni, Btissam; Boutimzine, Noureddine; Daoudi, Rajae

    2013-01-01

    La cataracte congénitale constitue la cause la plus fréquente de cécité évitable chez les enfants. Le but de cette étude est d’évaluer le pronostic réfractif et fonctionnel, des enfants opérés de cataracte congénitale avec implantation. Il s'agit d'une étude rétrospective de 108 enfants, dont 85 cataractes bilatérales, 23 unilatérales opérés entre 2007 et 2011. La réfraction a été mesurée à 1 mois, 3 mois, 6 mois, 1 an, 2 ans, 3 ans et/ou 4 ans en post-opératoire. La meilleure acuité visuelle corrigée, ainsi que l'incidence des complications post-opératoires ont été analysé. L’âge moyen de la chirurgie était de 25 mois avec une durée moyenne de suivi de 3,17 ans. Les complications retrouvées étaient l'inflammation, la prolifération secondaire, et le glaucome. L'acuité visuelle (AV) moyenne corrigée finale était de 5,75/10e pour les formes bilatérales, et de 4,16/10e pour les unilatérales (p = 0,001). Les facteurs de mauvais pronostic retrouvés étaient l’âge tardif de la chirurgie, la densité de la cataracte et la survenue de complications (p = 0,001). L'incidence des complications post-opératoires était significativement plus élevé chez les enfants opérés à un jeune âge (p = 0,001). Les facteurs de mauvais pronostic visuel chez les enfants opérés pour cataracte congénitale avec implantation, sont représentés par le caractère unilatéral de la cataracte, l’âge tardif de la chirurgie, la densité de la cataracte et la survenue de complications post opératoires. PMID:24672622

  4. La chirurgie du diaphragme sous aortique

    PubMed Central

    Moutakiallah, Younes; Maaroufi, Ilham; Aithoussa, Mahdi; Bamous, Mehdi; Abdou, Abdessamad; Atmani, Noureddine; Hatim, Abdedaïm; Amahzoune, Brahim; Bekkali, Youssef El; Boulahya, Abdelatif

    2016-01-01

    Le diaphragme sous aortique se caractérise par une certaine latence clinique et une faible morbi-mortalité. La chirurgie reste le traitement de choix malgré un réel risque de récurrence à long terme. Nous rapportons 18 patients opérés entre Avril 1994 et Mars 2011 pour diaphragme sous aortique d’âge moyen de 18,1±9,7 ans avec 11 patients de sexe masculin. Le diaphragme était de nature fibreuse chez 13 patients et fibro-musculaire chez 5 patients. Tous les patients ont été opérés par résection de diaphragme associée à une myectomie, une plastie aortique, une fermeture de communication interventriculaire et une ligature de canal artériel perméable respectivement chez 3, 3, 2 et 2 patients. La Mortalité opératoire était nulle et sans aucun cas de trouble de conduction postopératoire. Le suivi a duré en moyenne 44,3±36,8 mois sans aucun décès tardif. Deux patients ont présenté une récidive de diaphragme qui a nécessité une réopération avec bonne évolution. La tendance actuelle dans la chirurgie du diaphragme se fait vers des interventions précoces et des résections plus extensives. Cependant, le risque de récidive impose une surveillance échographique systématique et rapprochée. PMID:27516830

  5. La chirurgie réfractive de la cataracte: des technologies novatrices élargissent les choix des patients canadiens.

    PubMed

    Potvin, Richard

    2016-11-01

    La chirurgie de la cataracte a toujours consisté à extraire le cristallin opacifié de l'œil pour le remplacer par une lentille artificielle. Cette intervention rend la vision du patient plus nette, sans pour autant corriger l'erreur de réfraction, c'est-à-dire la nécessité de porter des lunettes ou des lentilles cornéennes après l'opération. Les instruments diagnostiques et chirurgicaux modernes permettent désormais de corriger ces erreurs de réfraction au moment de l'opération, ce qui a fait émerger une nouvelle notion, celle de la chirurgie réfractive de la cataracte. Même si cette correction n'est pas nécessaire sur le plan médical, de nombreux patients se réjouissent de la possibilité de ne plus porter de lunettes ou d'en porter moins après l'opération, même s'ils doivent engager des frais.

  6. Bloc auriculo-ventriculaire post chirurgie cardiaque: à propos de 23 cas

    PubMed Central

    Mouram, Sahar; Fellat, Ibtissam; Cherti, Mohamed

    2014-01-01

    Le bloc auriculo-ventriculaire (BAV) représente une complication non négligeable de la chirurgie cardiaque. Il est responsable de séquelles lourdes et graves compromettant le pronostic de la maladie et conduisant à la mise en place d'un stimulateur cardiaque définitif. Il est primordial d’étudier et de déterminer les différents facteurs prédictifs de BAV post opératoire, son histoire naturelle, son incidence ainsi que le délai exact de la mise en place d'un pacemaker. Notre étude est une étude rétrospective descriptive à propos de 23 patients opérés pour chirurgie cardiaque sous circulation extracorporelle entre octobre 1989 et août 2010 ayant présentés des troubles conductifs auriculo-ventriculaires en post opératoire. Plusieurs facteurs de risque ont été étudiés dans notre série, liés surtout à l'atteinte directe du noeud auriculo-ventriculaire ou à l'ischémie myocardique. Le délai d'apparition du trouble conductif ainsi que le délai d'implantation on été également étudié. Plusieurs facteurs favorisants de survenue de BAV ont été identifiés liés essentiellement au type de la cardiopathie opérée avec une prédominance de la cardiopathie congénitale, d'autres facteurs ont été rapportés notamment la présence d'hypertrophie ventriculaire gauche (HVG) de troubles conductifs en préopératoire, une durée du clampage aortique et de CEC prolongée. La moitié des patients ont présenté un BAV immédiat. Le délai d'implantation par rapport à la date de la découverte du BAV varie dans notre série d'une implantation immédiate après le diagnostic positif (J0) à un délai d'implantation allant jusqu’à 57 jours. Plusieurs facteurs de risques déterminent la survenue de BAV post chirurgie cardiaque, leur connaissance est primordial ainsi que le délai exact de l'implantation du stimulateur cardiaque définitif. PMID:25883725

  7. [Thoughts on the Revue de Chirurgie Plastique (1931-34) and the Revue de Chirurgie Structive (1935-38)].

    PubMed

    Vrebos, J

    2007-08-01

    The history of modern plastic surgery starts when a young, restless ENT man, Dr M. Coelst, started a training in Plastic Surgery with Sebileau in Paris and Joseph in Berlin. This man of vision and far-sighted imagination realized that the separated efforts and publications of so many pioneers, scaterred all over the world, would be lost if not gathered in a scientific journal only devoted to plastic surgery for the benefit of all. This brought him to the idea of establishing, in 1931, at his own initiative, the first international Journal of Plastic Surgery ever published, the Revue de Chirurgie Plastique, fifteen years before the USA Journal Plastic and Reconstructive Surgery and sixteen years before the British Journal of Plastic Surgery. The name of the journal was changed in 1935 to the Revue de Chirurgie Structive. Coelst' Revue was promptly accepted as the leading Journal of Plastic Surgery and all the internationally known plastic Surgeons contributed to it by scientific papers of great value, even today.

  8. U.S. plastic surgeons who contributed to the Revue de Chirurgie Plastique and the Revue de Chirurgie Structive (1931-1938): "Giants" in our specialty.

    PubMed

    Rogers, B O

    1999-01-01

    The Revue de Chirurgie Plastique and the Revue de Chirurgie Structive, Brussels (1931-1938), edited by Maurice Coelst, M.D. from Brussels, were the first, full-fledged medical publications specifically devoted to plastic, reconstructive, and aesthetic surgery. Publishing original articles by J.W. Maliniac, J. Eastman Sheehan, and brief summaries of papers read at plastic surgery societies by C.R. Straatsma, L.A. Peer, G. Aufricht, and other well-known American plastic surgeons, these Revues drew attention to surgeons, most of whom were responsible for organizing the American Society of Plastic and Reconstructive Surgeons in 1931, the same year in which the Revue de Chirurgie Plastique first appeared.

  9. British plastic surgeons who contributed to the Revue de Chirurgie Plastique and the Revue de Chirurgie Structive (1931-1938): "the Big Four" in their Speciality.

    PubMed

    Rogers, B O

    2001-01-01

    The Revue de Chirurgie Plastique and the Revue de Chirurgie Structive, Brussels (1931-1938), edited by Maurice Coelst, M.D. from Brussels, were the first, full-fledged medical publications devoted specifically to plastic, reconstructive, and aesthetic surgery. Publishing original articles by H.D. Gillies, P.T. Kilner, A.H. McIndoe, and R. Mowlem--the "Big Four" as they were known to both English and American plastic surgeons--the Revues drew attention to these four surgeons who were mainly responsible for developing the prestige of English plastic surgery in the early 1930s.

  10. Scientific contributions of U.S. plastic surgeons to the Revue de Chirurgie Plastique and the Revue de Chirurgie Structive, Brussels (1931-1938).

    PubMed

    Vrebos, J

    1999-01-01

    The author emphasizes the close cooperation between U.S. plastic surgeons and the first international journal entirely devoted to plastic surgery, the Revue de Chirurgie Plastique (1931-1934) later to become the Revue de Chirurgie Structive (1935-1938) published under the editorship of Maurice Coelst, M.D. from Brussels. By the accurate recording of original articles, book reviews, proceedings of their annual meetings and summaries in three different languages (English, French, German), the author stresses the intense scientific dynamism and the achievements made by the U.S. pioneers of this new speciality, which really started during World War I.

  11. APR-2 Tropical Cyclone Observations

    NASA Technical Reports Server (NTRS)

    Durden, S. L.; Tanelli, S.

    2011-01-01

    The Second Generation Airborne Precipitation Radar (APR-2) participated in the Genesis and Rapid Intensification Processes (GRIP) experiment in August and September of 2010, collecting a large volume of data in several tropical systems, including Hurricanes Earl and Karl. Additional measurements of tropical cyclone have been made by APR-2 in experiments prior to GRIP (namely, CAMEX-4, NAMMA, TC4); Table 1 lists all the APR-2 tropical cyclone observations. The APR-2 observations consist of the vertical structure of rain reflectivity at 13.4 and 35.6 GHz, and at both co-polarization and crosspolarization, as well as vertical Doppler measurements and crosswind measurements. APR-2 normally flies on the NASA DC-8 aircraft, as in GRIP, collecting data with a downward looking, cross-track scanning geometry. The scan limits are 25 degrees on either side of the aircraft, resulting in a roughly 10-km swath, depending on the aircraft altitude. Details of the APR-2 observation geometry and performance can be found in Sadowy et al. (2003).The multiparameter nature of the APR-2 measurements makes the collection of tropical cyclone measurements valuable for detailed studies of the processes, microphysics and dynamics of tropical cyclones, as well as weaker systems that are associated with tropical cyclone formation. In this paper, we give a brief overview of how the APR-2 data are processed. We also discuss use of the APR-2 cross-track winds to estimate various quantities of interest in in studies of storm intensification. Finally, we show examples of the standard products and derived information.

  12. APR-2 Tropical Cyclone Observations

    NASA Technical Reports Server (NTRS)

    Durden, S. L.; Tanelli, S.

    2011-01-01

    The Second Generation Airborne Precipitation Radar (APR-2) participated in the Genesis and Rapid Intensification Processes (GRIP) experiment in August and September of 2010, collecting a large volume of data in several tropical systems, including Hurricanes Earl and Karl. Additional measurements of tropical cyclone have been made by APR-2 in experiments prior to GRIP (namely, CAMEX-4, NAMMA, TC4); Table 1 lists all the APR-2 tropical cyclone observations. The APR-2 observations consist of the vertical structure of rain reflectivity at 13.4 and 35.6 GHz, and at both co-polarization and crosspolarization, as well as vertical Doppler measurements and crosswind measurements. APR-2 normally flies on the NASA DC-8 aircraft, as in GRIP, collecting data with a downward looking, cross-track scanning geometry. The scan limits are 25 degrees on either side of the aircraft, resulting in a roughly 10-km swath, depending on the aircraft altitude. Details of the APR-2 observation geometry and performance can be found in Sadowy et al. (2003).The multiparameter nature of the APR-2 measurements makes the collection of tropical cyclone measurements valuable for detailed studies of the processes, microphysics and dynamics of tropical cyclones, as well as weaker systems that are associated with tropical cyclone formation. In this paper, we give a brief overview of how the APR-2 data are processed. We also discuss use of the APR-2 cross-track winds to estimate various quantities of interest in in studies of storm intensification. Finally, we show examples of the standard products and derived information.

  13. Antibioprophylaxie dans les chirurgies gynécologiques et obstétricales propres et propres contaminées à l'Hôpital Général de Yaoundé, Cameroun

    PubMed Central

    Ngowa, Jean Dupont Kemfang; Ngassam, Anny; Mbouopda, R Motzebo; Kasia, Jean Marie

    2014-01-01

    Introduction Il s'agira de déterminer l'incidence et les facteurs associés à l'infection post opératoire dans les chirurgies gynécologiques et obstétricales propres et propres contaminées. Méthodes Étude de cohorte prospective axée sur la surveillance de l'infection post opératoire chez les patientes opérées d'une chirurgie gynécologique ou obstétricale propre ou propre contaminée au Service de Gynécologie B de l'Hôpital Général de Yaoundé, après une antibioprophylaxie avec la cefazoline. La période d’étude de 18 mois s'est étalée de janvier 2012 à juin 2013. La surveillance des patientes opérées se poursuivait sur les 30 premiers jours post opératoires. Résultats Au total 211 patientes opérées d'une chirurgie gynécologique ou obstétricale propre ou propre contaminée ont été enrôlées dans cette étude. La moyenne d’âge des patientes était de 35,4 ±10 ans; les chirurgies propres contaminées représentaient 76,3% et les chirurgies propres 23,7%. Nous avons observé au total 06 (2,8%) cas d'infection post opératoire, dont 03 (1,4%) cas d'infection du site opératoire, 02 (0,95%) cas d'infection urinaire et 01(0,47%) cas d'infection pulmonaire. Les variables significativement associées à l'infection post opératoire étaient la durée de la chirurgie (durée moyenne: 126± 89min vs 82± 50 min; p< 0,04) et le diabète (OR. 40,8; IC à 95%. 2,2-749,2; p < 0,000. Conclusion Notre taux d'infection post opératoire global de 2,8% et d'infection du site opératoire de 1,4% vient renforcer les données de la littérature sur l'efficacité de l'antibioprophylaxie dans les chirurgies gynécologiques et obstétricales propres et propres contaminées en milieu africain. Cependant le respect des principes d'asepsie péri opératoire et une sélection précise de la classe de chirurgie devraient être de règle dans notre contexte. PMID:25667685

  14. Respirators: APR Issuer Self Study 33461

    SciTech Connect

    Chochoms, Michael

    2016-07-13

    Respirators: APR Issuer Self-Study (course 33461) is designed to introduce and familiarize employees selected as air-purifying respirator (APR) issuers at Los Alamos National Laboratory (LANL) with the responsibilities, limitations, procedures, and resources for issuing APRs at LANL. The goal is to enable these issuers to consistently provide proper, functioning APRs to authorized users

  15. The scientific contributions of British Plastic Surgeons to the Revue de Chirurgie Plastique and the Revue de Chirurgie Structive, Brussels (1931-1938).

    PubMed

    Vrebos, J

    2001-01-01

    In 1931, Maurice Coelst, M.D. from Brussels started the publication of the first international journal of plastic surgery ever published: the Revue de Chirurgie Plastique (1931-1934), which eventually became the Revue de Chirurgie Structive (1935-1938). In 1936, he established the first European Society of Structive Surgery, which held its first congress in Brussels. Further congresses were held in London in 1937 and in Milan in 1938. It is the collaboration and the participation of British plastic surgeons in this Society, this journal, and these meetings that I want to stress, because I am firmly convinced that these documents fill a gap in the history of Plastic Surgery in Great Britain, since--as far as I know--no detailed information concerning this period was ever published in Plastic Surgery literature.

  16. Réponse radiologique complète d'un hémangiopéricytome méningé après radiothérapie adjuvante à une exérèse incomplète

    PubMed Central

    Bazine, Amine; Ogandaga, Etienne; Dossou, Serpos; Aissa, Abdellah; Oumellal, Jamal; Lalya, Issam; Saidi, Amar; Kebdani, Tayeb; Benjaafar, Noureddine

    2014-01-01

    L'hémangiopéricytome méningé (HM) est une tumeur vasculaire rare qui représente moins de 1% des tumeurs intracrâniennes. Son traitement reste à ce jour mal codifié et n'est basé que sur des données rétrospectives. La place de la radiothérapie adjuvante après chirurgie d'exérèse n'est pas bien établie. Ce présent travail décrit un cas d'HM chez une patiente de 42 ans, traité par chirurgie incomplète et radiothérapie adjuvante, avec réponse radiologique complète notée 1 an après la fin du traitement. PMID:25379118

  17. Résultats de la chirurgie avancée de la cataracte par tunnélisation: à propos de 262 cas réalisés au CHR de Banfora (Burkina Faso)

    PubMed Central

    Djiguimdé, Pierre Windinmanégdé; Diomandé, Ibrahim Abib; Ahnoux-Zabsonré, Ahgbatouhabéba; Koffi, Konan Virgile; Meda, Tierinyê Armand; Diomandé, Gossé François; Sanou, Jerôme; Meda-Hien, Gertude; Sankara, Paté; Meda, Nonfounikoun

    2015-01-01

    La cataracte demeure la première cause de cécité dans les pays en voie de développement posant un problème de santé publique. Le but de cette étude est de faire le bilan d'une activité de chirurgie avancée de la cataracte par la technique dite de « phacoalternative » ou par tunnélisation. Il s'agissait d'une étude prospective de base réalisée au Burkina Faso portant sur la chirurgie de la cataracte par la technique de tunnélisation. L’âge moyen de nos patients atteints de cataracte était de 62,47 ± 12,77 ans avec un sex-ratio de 0,98. La majorité des patients opérés (82,82%) étaient des cultivateurs et des ménagères. L'acuité visuelle de loin était réduite à la perception lumineuse dans 68,70% des cas. La profondeur moyenne de la chambre antérieure était de 2,98 ± 0,53 mm. L’épaisseur moyenne du cristallin était de 3,55 ± 0,75 mm. La longueur axiale moyenne de l’œil de nos patients opérés de la cataracte était de 22,88 ± 0,90 mm. La puissance réfractive moyenne estimée de la cornée était de 43,21 ± 2,03 dioptries chez nos patients. La puissance moyenne estimée de l'implant intra oculaire (IOL) utilisé était de23,11 ± 2,35D. La majorité (79,6%) de nos patients avait une bonne acuité visuelle après la chirurgie de la cataracte par tunnélisation. La chirurgie de la cataracte par tunnélisation est une technique révolutionnaire adaptée aux pays pauvres d'Afrique. Elle permet une lutte efficace à moindre coût contre la cécité par cataracte dans nos régions. La tunnélisation est une technique chirurgicale adaptée pour lutter efficacement contre la cécité due à la cataracte en Afrique. PMID:27022426

  18. Arrêt cardiaque au cours d'une chirurgie de kyste hydatique du foie

    PubMed Central

    Ouzzad, Omar; Kechna, Hicham; Moudden, Mohamed Karim; Chkoura, Khalid; Hanafi, Sidi Mohamed

    2015-01-01

    L'hydatidose est une pathologie fréquente qui reste encore endémique au Maroc. Sa localisation privilégiée est le foie. Son traitement repose essentiellement sur la chirurgie. Celui-ci est parfois incriminé dans la survenue de réactions allergiques sévères pouvant menacer le pronostic vital. Nous rapportons un nouveau cas de réaction anaphylactique sévère de grade IV peropératoire au cours d'une chirurgie de kystes hydatiques multiples du foie. Nous insistons sur la nécessité de sa reconnaissance rapide afin d'instaurer rapidement un traitement efficace. La prévention de cet accident est basée sur des précautions chirurgicales pour éviter les fuites ou les ruptures accidentelles peropératoires des kystes hydatiques. PMID:26664533

  19. From Archiv für Klinische Chirurgie to Langenbeck's Archives of Surgery: 1860-2010.

    PubMed

    Beger, H G

    2010-04-01

    In February 1860, B. Langenbeck, Th. Billroth, and G. Gurlt certified in Berlin with the publisher A. Hirschwald the founding of Archiv für Klinische Chirurgie. The journal published extended reports about application of new and case-proven surgical procedures. Separate sections were dedicated to surgical casuistics and small surgical communications and report of surgical institutions from Germany, Austria, and Switzerland as well as annual statistical reports of hospitals. Beginning with the first issue, the Archive was an international journal with the focus on gastrointestinal, trauma, orthopedic, thyroid, and vascular surgery. A section Achievements and Progress in Surgery referred to published results in national and international medical and surgical journals. Surgeons from Germany contributed strongly to the rise of operative treatment concepts in the second half of the nineteenth century by new surgical procedures, many of them published in the Archiv für Klinische Chirurgie. Since 1923, the German Society of Surgery took Archiv für Klinische Chirurgie as the official journal of the society. Beginning 1950, Langenbeck's published in a separate supplement the proceedings of the annual congress of the German Society of Surgery. A second supplement published since 1972 focused exclusively on reporting of research work presented in the section of Surgical Forum for Experimental and Clinical Surgery. After World War II, Langenbeck's Archiv für Chirurgie gained acceptance as the leading scientific surgical journal in Germany. Since 1998, the concept of Langenbeck's Archiv was completely changed to an English journal with the title Langenbeck's Archives of Surgery. In the last 12 years, Langenbeck's has turned to an international German-surgery-based electronic journal. Langenbeck's Archives of Surgery experienced an increasing international reputation; in 2001, only two non-American journals (British Journal of Surgery and Langenbeck's) belonged to the top

  20. Evaluating SPP/APR Improvement Activities

    ERIC Educational Resources Information Center

    National Early Childhood Technical Assistance Center (NECTAC), 2009

    2009-01-01

    This document is intended to assist State Education Agency (SEA) and Lead Agency (LA) staff and technical assistance providers in designing a meaningful evaluation for the State Performance Plan (SPP)/Annual Performance Report (APR) improvement activities. It provides: (1) information about the relevance of evaluation in the context of improvement…

  1. La chirurgie coronaire sous circulation extra-corporelle chez le patient diabétique

    PubMed Central

    Moutakiallah, Younes; Benzaghmout, Khadija; Aithoussa, Mahdi; Atmani, Nourreddine; Amahzoune, Brahim; Hatim, Abdedaim; Drissi, Mohamed; Benyass, Aatif; ElBekkali, Youssef; Boulahya, Abdelatif

    2014-01-01

    Nous rapportons les résultats de la chirurgie coronaire chez une population de coronariens diabétiques opérés sous circulation extra-corporelle dans le service de chirurgie cardiaque de l'hôpital militaire d'instruction Mohammed V de Rabat. C'est une étude rétrospective menée entre Janvier 2008 et Février 2012 (4 ans), portant sur 103 patients diabétiques consécutifs opérés pour pontage coronaire. L’âge moyen des patients était de 61±8,7ans (37-82ans) avec un sexe ratio (H/F) de 3,9. Tous les patients diabétiques de type 2 et sous traitement anti-diabétique ont été inclus dans cette étude. La sténose du tronc commun gauche était présente chez 26,2% des patients et 53,4% étaient tritronculaires. Quatre-vingt patients (78,6%) étaient insulino-nécessitant, l'Euro-score moyen était de 1,63±1% et le nombre moyen de pontage de 2,3±0,7. Les durées moyennes de la circulation extra-corporelle et du clampage aortique étaient respectivement de 134,4 ± 42 min et 76 ± 28 min. La mortalité hospitalière était de 2 décès (1,9%), les durées moyennes de ventilation artificielle, du séjour en réanimation et du séjour postopératoire étaient respectivement de 7h (5-16h), 48h (42-52h) et 15,6 ± 8,6 jours. Les complications postopératoires étaient l'infarctus du myocarde, l'infection de paroi, la médiastinite et le bas débit cardiaque chez respectivement 1,9%, 10,7%, 3,9% et 1,9% des patients. Il ressort de notre étude, que les facteurs prédictifs d'infection post opératoire étaient la durée de ventilation artificielle (p = 0,002), la durée de la circulation extra-corporelle (p < 0,001) en plus du tabac (p = 0,004) et de l'obésité (p = 0,005). Les patients ont été contactés par téléphone ou lors de la consultation régulière de contrôle. Le taux de suivi a atteint 92,1% et la survie à 2 ans était de 98,9% des patients contrôlés avec une mortalité tardive de 1% avec un décès suite à un accident vasculaire c

  2. Pratique anesthésique à Lubumbashi: indications, types de chirurgie et types de patient

    PubMed Central

    Kabey, Alain Kabey a; Lubanga, Muyumba; Tshamba, Mundongo; Kaut, Mukeng; Kakambal, Kaij; Muteya, Manika; Manzanza, Kilembe; Kalal, Kapend

    2015-01-01

    Introduction Cette étude a pour objectif de décrire la pratique anesthésique dans un pays à faible revenu et où le plateau technique anesthésique est moins équipé. Méthodes Une étude descriptive transversale a été menée durant l'année 2013. L'enquête a concerné les pratiques anesthésiques, les indications chirurgicales et les caractéristiques des malades. L'encodage et l'analyse des données ont été réalisées grâce aux logiciels Epi Info 3.5.3 et Excel 2010. Résultats Nous avons enregistré 2358 patients dont l’âge médian était de 29 + 15 ans, avec 81,5% âgés de 11 à 50 ans. Parmi eux, 67,3% des malades étaient du sexe féminin. Dans ensemble, 62,5% de ces patients étaient pris en charge pour les interventions programmées. L’évaluation du risque anesthésique a montré que 91,9% des patients étaient de la classe ASA I et II. La chirurgie la plus pratiquée était viscérale (46,7%) suivie de la chirurgie gynéco-obstétricale (29,2%). Les différents types d'anesthésie étaient les suivants: anesthésie générale (87,6%), locorégionale (11,8%) et combinée (0,6%). Conclusion La pratique anesthésique dans la population d’étude était dominée par l'anesthésie générale. Les malades étaient au trois quart de sexe féminin et de la classe ASA I et II. Les résultats de cette étude indiquent la nécessité d’évaluer l'issue de cette pratique. La pratique anesthésique à Lubumbashi est tributaire du plateau technique, des compétences du personnel et de l'acceptabilité du type d'anesthésie par les patients. PMID:26523180

  3. Characterization of AprE176, a fibrinolytic enzyme from Bacillus subtilis HK176.

    PubMed

    Jeong, Seon-Ju; Heo, Kyeong; Park, Ji Yeong; Lee, Kang Wook; Park, Jae-Yong; Joo, Sang Hoon; Kim, Jeong Hwan

    2015-01-01

    Bacillus subtilis HK176 with high fibrinolytic activity was isolated from cheonggukjang, a Korean fermented soyfood. A gene, aprE176, encoding the major fibrinolytic enzyme was cloned from B. subtilis HK176 and overexpressed in E. coli BL21(DE3) using plasmid pET26b(+). The specific activity of purified AprE176 was 216.8 ± 5.4 plasmin unit/mg protein and the optimum pH and temperature were pH 8.0 and 40°C, respectively. Error-prone PCR was performed for aprE176, and the PCR products were introduced into E. coli BL21(DE3) after ligation with pET26b(+). Mutants showing enhanced fibrinolytic activities were screened first using skim-milk plates and then fibrin plates. Among the mutants, M179 showed the highest activity on a fibrin plate and it had one amino acid substitution (A176T). The specific activity of M179 was 2.2-fold higher than that of the wild-type enzyme, but the catalytic efficiency (kcat/Km) of M179 was not different from the wild-type enzyme owing to reduced substrate affinity. Interestingly, M179 showed increased thermostability. M179 retained 36% of activity after 5 h at 45°C, whereas AprE176 retained only 11%. Molecular modeling analysis suggested that the 176(th) residue of M179, threonine, was located near the cation-binding site compared with the wild type. This probably caused tight binding of M179 with Ca(2+), which increased the thermostability of M179.

  4. [Georges Mareschal (1658-1736) the founder of the Académie de Chirurgie].

    PubMed

    Peumery, J J

    1996-01-01

    Georges Mareschal born in 1658 was the son of an Irish gentleman serving in the army of Louis XIII: John Marshall ennobled after the battle of Rocroi (1643) with a francisation of his name. He came to Paris in 1677 and worked with a master-surgeon: Le Breton. He went at the Charité hospital in 1684, was received master-surgeon in 1688 and became there chief-surgeon in 1692. He modified and improved lithotomy. After having operated several personalities and king Louis XIV he became his first surgeon in 1703, later "Maître d'Hôtel" in 1706 and was finally ennobled in 1707. He visited regularly sick people belonging to all classes of society in the Versailles area and played a part in the "poisons affair" in 1712. He remained the First Surgeon of Louis XV and received the cross of Saint-Michel order in 1723. He created with La Peyronie a School of Surgery in Paris officialized by patent letters in 1726. With the help of the same collaborator he founded in 1731 the "SociétéAcademique des chirurgiens de Paris" which will become in 1748 the "Académie Royale de Chirurgie" after his death and that of La Peyronie who had been nominated himself First Surgeon.

  5. Inactivation of aprE Gene in Bacillus subtilis 168 by Homologus Recombination

    PubMed Central

    Rabbani, Mohammed; Soleymani, Safoura; Sadeghi, Hamid Mir Mohammad; Soleimani, Narjes; Moazen, Fatemeh

    2014-01-01

    Background One of the most important producers of high quality industrial enzymes is the Gram-positive bacterium, Bacillus subtilis (B. Subtilis). One major limitation that hinders the wide application of B. subtilis is the secretion of high levels of extracellular proteases which degrade the secreted foreign proteins. In this study, homologus recombination technique was used to knock out its protease gene, aprE. Methods The internal segment of the pro-sequence of aprE gene of B. subtilis 168 with a length of 80 bps and its complementary sequence were synthesized and ligated into pUB110 at EcoR1 and XbaI restriction sites. Competent cells of B. subtilis 168 were prepared and transformed by electroporation using Bio Rad gene pulser as explained in the methods section. Transformants carrying the recombinant plasmid were selected for resistance to neomycin. The success of homologous recombination was checked by PCR amplification of the neomycin gene which was part of the vector and did not exist in the genome of B. subtilis 168. The protease activity was measured using the Protease Fluorescent Detection Kit based on the proteolytic hydrolysis of fluorescein isothiocyanate (FITC)–labeled casein-substrate. Results The results demonstrated that aprE gene would not be able to produce further active subtilisin E. The reduction of protease activity also confirmed the efficacy of the induced mutation in this gene. Conclusion It will therefore be a major challenge for future research to identify and modulate quality control systems of B. subtilis which limit the production of high quality protease- sensitive products such as lipase. PMID:25215183

  6. Alkaline serine protease AprE plays an essential role in poly-γ-glutamate production during natto fermentation.

    PubMed

    Kada, Shigeki; Ishikawa, Atsushi; Ohshima, Yoshifumi; Yoshida, Ken-ichi

    2013-01-01

    Natto is a traditional Japanese food made from soybeans fermented by natto starter strains of Bacillus subtilis natto. It has been suggested that extracellular protease activity released by the bacteria are involved in the production of poly-γ-glutamate (γ-PGA) during natto fermentation. One of the natto starters, strain r22, possesses at least seven genes, each of which encoded an extracellular protease orthologous to its counterpart in B. subtilis 168, aprE, bpr, epr, mpr, nprE, vpr, and wprA, but it was found to lack nprB. Inactivating the aprE ortholog alone resulted in a severe decrease in γ-PGA production and in the total extracellular protease activity. The defect in γ-PGA production of the mutant lacking the aprE ortholog was complemented when the medium was supplemented with sufficient glutamate. These results suggest that the alkaline serine protease encoded by aprE plays an indispensable role in supplying materials to produce γ-PGA. On the other hand, simultaneous inactivation of all the protease genes except for aprE did not significantly affect either γ-PGA production or total protease activity.

  7. Soins Aux Brules Apres Un Accident Nucleaire

    PubMed Central

    Bargues, L.; Donat, N.; Jault, P.; Leclerc, T.

    2010-01-01

    Summary Les lésions radiques sont dues le plus souvent à des radio-isotopes utilisés dans l’industrie. L’explosion d’un réacteur nucléaire, les armes nucléaires ou une attaque terroriste constituent un risque d’afflux massif de victimes brûlées. Les radiations ionisantes occasionnent des brûlures thermiques, des syndromes d’irradiation aiguë avec pancytopénie et des signes cutanés retardés. Après une période de latence, des symptômes cutanés apparaissent et leur profondeur est proportionnelle à la dose reçue. Les protocoles habituels de réanimation des brûlés s’appliquent ici. Les soins aux irradiés nécessitent aussi une mesure de l’irradiation et une décontamination par des personnels entraînés. En cas de catastrophe nucléaire, la priorité est d’optimiser les structures existantes et de préserver les moyens pour les patients ayant la plus forte probabilité de survie. Après un accident nucléaire isolé, les difficultés dans les centres de brûlés sont l’évaluation de la profondeur et les techniques chirurgicales de couverture cutanée. La préparation des moyens médicaux et des centres de brûlés est nécessaire pour faire face à la prise en charge de ces brûlures différentes et complexes. PMID:21991218

  8. Place de la chirurgie dans la prise en charge des cancers du sein chez la femme au Centre Hospitalier Universitaire Yalgado Ouedraogo: à propos de 81 cas

    PubMed Central

    Zongo, Nayi; Millogo-Traore, Timonga Françoise Danielle; Bagre, Sidpawalmdé Carine; Bagué, Abdoul-Halim; Ouangre, Edgar; Zida, Maurice; Bambara, Aboubacar; Bambara, Tozoula Augustin; Traoré, Si Simon

    2015-01-01

    Etudier la place de la chirurgie dans la prise en charge des cancers du sein au centre hospitalier universitaire Yalgado Ouédraogo. Nous avons réalisé une étude prospective et descriptive sur dix (10) mois portant sur la place de la chirurgie dans le cancer du sein. Elle a eu pour cadre les services de gynécologie-obstétrique et de chirurgie viscérale et digestive du centre hospitalier universitaire Yalgado Ouédraogo. Ont été pris en compte les indications, les gestes et les résultats de la chirurgie. Nous avons colligé 81 cancers mammaires. Le délai moyen de consultation a été de 14,26 mois. Les tumeurs T3 à T4 représentaient 82,71% des cas. Trente-huit patientes (46,91%) ont été opérées. La chimiothérapie néo adjuvante a été réalisée dans 29,63% des cas. Trente-quatre patientes (41,97%) étaient opérables d'emblée. Il s'agissait de mastectomie selon Madden dans 94,74% des cas et de chirurgie de propreté dans 2 cas (5,26% des cas). Une chimiothérapie adjuvante a été réalisée chez 52,63% des patientes opérées. Des complications à type de lymphocèle ont été notées dans 23,68% des cas. Leur traitement a consisté en des ponctions évacuatrices. Les indications de la chirurgie sont limitées par le retard diagnostique corollaire de stades avancés des cancers du sein. L'absence de la radiothérapie rend délicate la pratique de la chirurgie conservatrice et la mastectomie occupe toujours une place importante. Un diagnostic précoce permettrait d'augmenter les indications chirurgicales. PMID:26848364

  9. 5. Historic American Buildings Survey Roger Sturtevant, Photographer Apr. 5, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Historic American Buildings Survey Roger Sturtevant, Photographer Apr. 5, 1934 JACOB R. GIDDIS AND JOEL A. CUMBACK, MOUNTAIN VIEW CEMETERY, COLUMBIA - Grave Stones, Mountain View Cemetery, Bigler Street, Columbia, Tuolumne County, CA

  10. 12. Historic American Buildings Survey Arthur C. Haskell, Photographer Apr. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Historic American Buildings Survey Arthur C. Haskell, Photographer Apr. 1, 1939 (l) INT.- STAIRWAY, 4th FLOOR, LOOKING SOUTH - M.I.T., Rogers Building, 491 Boylston Street, Boston, Suffolk County, MA

  11. L'endométriose pariétale cicatricielle après césarienne: une entité rare

    PubMed Central

    El Fahssi, Mohammed; Lomdo, Massama; Bounaim, Ahmed; Ali, Abdelmounaim Ait; Sair, Khalid

    2016-01-01

    L'endométriose de la paroi est une entité clinique rare, dont la physiopathologie demeure imprécise. Elle survient le plus souvent après une intervention chirurgicale gynécologique ou obstétricale. Nous rapportons le cas d'une patiente présentant une douleur cyclique, au niveau de la cicatrice de césarienne, Avec à l'examen clinique une masse de 5cm localisée au niveau de la fosse iliaque droite. la tomodensitométrie montre une masse de densité tissulaire de 45mm de grand axe. D'où la décision d'excision large de la lésion dont l’étude anatomopathologique confirme le diagnostic d'endométriose pariétale. Les suites postopératoires étaient simples avec un recul de 20 mois sans récidive de la masse ni de la douleur. A travers notre cas, nous insisterons sur les caractéristiques de cette pathologie, ce qui permettra au praticien de comprendre l'intérêt du diagnostic et de la prise en charge précoce de cette affection ainsi que la possibilité de sa prévention au cours de chaque chirurgie gynécologique ou obstétricale. PMID:27642418

  12. Revision of testing criteria for air cleaning unit of renovated APR-1000 and APR-1400 NPPS.

    PubMed

    Jeong, Seung-Young

    2011-07-01

    Designing Air Cleaning Units (ACU) of an Engineered Safety Feature and normal atmosphere clean-up system at the renovated APR-1000 and APR-1400 NPP, and fuel cycle facilities in Korea, is required to meet the standards of ASME AG-1 (1997), ASME N509/N510 (1989) and KEPIC-MH (2001) to enhance the removal efficiency of aerosols and particulates from the effluents. The revised ACU testing criteria are allowed to use alternative challenge agents of the dioctyl phthalate and Refrigerant-11 for in situ testing of high efficiency particulate air filters and adsorption banks. The operability testing time of engineered safety feature (ESF) trains was changed from 10 h to 15 min. The activated carbon in adsorption banks should undergo laboratory tests at a temperature of 30 °C and relative humidity 95 %. The removal criteria of methyl iodide should be over 99.5 % for ESF and 99 % for normal systems. This paper provides the background of the changed criteria for designing and testing of the ACU system in nuclear facilities.

  13. Les myélopathies cervicarthrosiques: résultat clinique et radiologique de la chirurgie sur une série de 135 patients opérés au service de neurochirurgie CHU Avicenne

    PubMed Central

    Djoubairou, Ben Ousmanou; Nabil, Moussé; Karekezi, Claire; Diawara, Seylan; El Fatemi, Nizar; Gana, Rachid; El Abbadi, Najia; Maaqili, Moulay Rachid

    2014-01-01

    La myélopathie cervicarthrosique est un syndrome clinique en relation avec la diminution des dimensions du canal rachidien, la cervicarthrose est l’étiologie principale après 50 ans. L'objectif du traitement est de rétablir les dimensions du canal rachidien cervical. Le choix de la technique chirurgicale sera guidé par l'analyse des signes cliniques, imageries, pré opératoire en fonction de laquelle sera pratiquée soit la voie antérieure, postérieure, ou exceptionnellement la voie combinée. Notre étude a pour but dans un premier temps d’évaluer à long terme les résultats cliniques et radiologiques de la chirurgie ensuite répondre à cette préoccupation: La lordose cervicale pré opératoire et postopératoire sont t-elles des facteurs de bon pronostic? Nous rapportons une étude rétrospective entre 2000 et 2013 portant sur 135 patients opérés dans notre formation et remplissant les critères inclusions. La collecte des données s'est faite en s'aidant du dossier médical des patients (échelle d'Association des orthopédistes Japonais), Imagerie (Radio, TDM, IRM), mesure de l'angle de courbure rachidienne en pré et postopératoire, ceci dans le but d’évaluer à long terme les résultats clinique et radiologique de la chirurgie. Ont été inclus dans notre étude 135 patients, 82 Hommes (60%), 53 femmes (40%) avec un âge moyen de 52 ans, ayant consulté pour des motifs divers (Névralgies cervicobrachiales, lourdeur des membres, troubles génito-sphinctériens). Soixante cinq patients (48%) ont bénéficié d'un abord antérieur (dissectomie, cloward, somatotomie médiane), 64 patients (47%) ont été opérés par voie postérieure (laminectomie de 1 à 3 niveaux) et 6 patients (5%) ont bénéficié d'un abord combiné dans un délai moyen de 3 mois devant la persistance des symptômes. Le niveau cervical le plus touché était C5C6 suivie de C4C5. L’évolution globale de nos patients était favorable dans 58% des cas, stationnaire

  14. Migration pelvienne de broche guide dans la chirurgie des fractures de hanche: à propos de 3 cas

    PubMed Central

    Guèye, Mohamadou Lamine; Thiam, Ousmane; Touré, Alpha Oumar; Seck, Mamadou; Cissé, Mamadou; Kâ, Ousmane; Dieng, Madieng; Dia, Abderahmane; Touré, Cheikh Tidiane

    2015-01-01

    La migration de matériel d'ostéosynthèse est une complication bien connue du traitement chirurgical des fractures. Toutefois, la migration pelvienne de broche guide dans la chirurgie des fractures de la hanche est un incident rare et potentiellement grave. Nous rapportons 3 observations dans lesquelles on notait une migration de broche guide dans le pelvis lors d'une ostéosynthèse dela hanche de type DHS. L'indication chirurgicale était une fracture per-trochantérienne dans 2 cas et une fracture du col fémoral type 4 de Garden dans 1 cas. Une minilaparotomie permettait d'objectiver une plaie du ligament large gauche et un hématome ligamentaire dans 1 cas, tandis que dans les 2 autres cas, il n'y avait pas de lésion viscérale. L'extraction de la broche a été effectuée dans les 3 cas. Les suites opératoires ont été simples chez tous les patients. PMID:26327949

  15. Les facteurs prédictifs de morbimortalité chez les patients sous ballon de contre pulsion intra-aortique en chirurgie cardiaque

    PubMed Central

    Elahmadi, Brahim; Motiaa, Youssef; Hatim, Abdedaim Elghadbane; Atmani, Noureddine; Moutakillah, Younes; Wahid, Fouad Amal; Elbekkali, Youssef; Houssa, Mahdi Ait; Razine, Rachid; Boulahya, Abdelatif; Drissi, Mohammed

    2015-01-01

    Le ballon de contre pulsion intra-aortique (BCPIA) est fréquemment utilisé en chirurgie cardiaque, comme moyen d'assistance circulatoire en cas de bas débit cardiaque. Il est d'intérêt clinique de déterminer les facteurs pronostiques chez les patients porteurs d'un BCPIA en chirurgie cardiaque, et qui restent un sujet rarement élucidé dans la littérature. L'objectif de notre travail est de déterminer les facteurs prédictifs de morbi-mortalité chez les patients sous ballon de contre pulsion intraortique en périopératoire d'une chirurgie cardiaque. Il s'agit d'une étude rétrospective portant sur l'ensemble des patients opérés en chirurgie cardiaque sous circulation extracorporelle, et ayant bénéficiés de la mise en place d'un ballon de contre pulsion intra-aortique en périopératoire, au service de chirurgie cardiovasculaire de l'Hôpital Militaire Mohamed V de Rabat, entre le mois de janvier 2005 et le mois d'aout 20014. Soixante dix patients ont été inclus dans notre étude. En analyse univariée l'âge, la dyspnée de stade III et IV, l'insuffisance cardiaque, la présence d'un infarctus du myocarde, d'une coronaropathie mono et bitronculaire, les anomalies du doppler de trons supra-aortique et du membre inférieur, le caractère urgent de la chirurgie, la durée de la circulation extracorporelle, l'instabilité hémodynamique postopératoire, le saignement et l'insuffisance rénale postopératoire étaient statistiquement associés à une mortalité postopératoire élevée. La dyskinésie préopératoire et la sortie de circulation extracorporelle sous drogues étaient associées à une morbidité globale élevée. En analyse multi variée, seule l'âge, constituait un facteur de risque indépendant de mortalité dans notre série avec un Odds Ratio (OR): 1,89 ; un Intervalle de Confiance (IC) 95% de (1,52-4,97) et un p =0,045. Au terme de notre étude, le taux de mortalité était de 48,57% et de morbidité globale était de 87,1%. Il

  16. 15 CFR 781.3 - Scope of the APR.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Regulations or APR implement certain obligations of the United States under the Protocol Additional to the Agreement Between the United States of America and the International Atomic Energy Agency Concerning the Application of Safeguards in the United States of America, known as the Additional Protocol. (a) Persons and...

  17. Epiplooplastie médiastinale dans le traitement d'une médiastinite post chirurgie cardiaque: à propos d'un cas

    PubMed Central

    Labsaili, Hicham; Borik, Waseem; Demondion, Pierre; Leprince, Pascal

    2014-01-01

    Nous rapportons le cas d'un patient diabétique et obèse, opéré d'une chirurgie de revascularisation myocardique avec l'utilisation des deux artères mammaires internes comme greffon. L'intervention s'est compliquée d'une médiastinite traitée premièrement à thorax fermé et secondairement par une épiplooplastie. Cette technique reste efficace dans les médiastinites graves et délabrantes. Tout chirurgien cardiaque et digestif doit la connaitre. PMID:25883735

  18. Implementation and Analysis for APR1400 Soft Control System

    SciTech Connect

    2015-07-01

    Due to the rapid advancement of digital technology, the definite technical advantages of digital control system compared to analog control system are accelerating the implementation of advanced distributed digital control system in the nuclear power plant. One of the major advantages of digital control system is the capability of Soft Control System. The design of Soft Control System for Advanced Power Reactor 1400 (APR1400) plant of Man-Machine Interface System (MMIS) is based on full digital technologies to enhance reliability, operability and maintainability. Computer-based compact workstation has been adopted in the APR1400 Main Control Room (MCR) to provide convenient working environment. This paper introduces the approaches and methodologies of Soft Control System for the Advanced Control Room (ACR). This paper also explains major design features for operation and display of the Soft Control System and its implementation to cope with regulatory requirements. (authors)

  19. Récidive après dix ans de tumeur de granulosa de l’ovaire: à propos de deux cas et revue de la littérature

    PubMed Central

    Majdoul, Soufya; Tawfiq, Nezha; Bourhaleb, Zouhour; Naqos, Nora; Taleb, Amina; Bouchbika, Zineb; Benchakroun, Nadia; Jouhadi, Hassan; Sahraoui, Souha; Benider, Abdelatif

    2016-01-01

    Les tumeurs à cellules de la granulosa (TG) de l’ovaire sont des tumeurs rares appartenant au groupe des tumeurs des cordons sexuels et du stroma. Elles représentent 0,6 à 3 % de l’ensemble des tumeurs de l’ovaire et 5 % des tumeurs malignes On distingue deux types: le type juvénile (TGJ) qui se caractérise par son agressivité et le type adulte (TGA) qui est le type le moins agressif et le plus fréquent. Les rechutes de TG de l'ovaire surviennent généralement dans les cinq ans, elles sont rarement sous forme de métastases péritonéales ou locales. Bien que, des options de traitement y compris la chirurgie avec ou sans chimiothérapie et ou radiothérapie ont été rapportés pour le traitement des récidives des TG, il n'y a aucune prise en charge standardisée de récidive de cette maladie. Ici, nous rapportons notre stratégie thérapeutique dans la prise en charge des récidives tardives, après dix ans, de la TG sous forme de carcinose péritonéale pour deux patientes avec une revue de la littérature. PMID:28154722

  20. Review of APR+ Level 2 PSA. Revision 2

    SciTech Connect

    Lehner, John R.; Mubayi, Vinod; Pratt, W. Trevor; Kim, Do Sam; Cho, Yong Jin; Cho, Sang Jin; Kim, In Goo

    2012-02-17

    Brookhaven National Laboratory (BNL) assisted the Korea Institute of Nuclear Safety (KINS) in reviewing the Level 2 Probabilistic Safety Assessment (PSA) of the APR+ Advanced Pressurized Water Reactor (PWR) prepared by the Korea Hydro & Nuclear Power Co., Ltd (KHNP) and KEPCO Engineering & Construction Co., Inc. (KEPCO-E&C). The work described in this report involves a review of the APR+ Level 2 PSA submittal [Ref. 1]. The PSA and, therefore, the review is limited to consideration of accidents initiated by internal events. As part of the review process, the review team also developed three sets of Requests for Additional Information (RAIs). These RAIs were provided to KHNP and KEPCO-E&C for their evaluation and response. This final detailed report documents the review findings for each technical element of the PSA and includes consideration of all of the RAIs made by the reviewers as well as the associated responses. This final report was preceded by an interim report [Ref. 2] that focused on identifying important issues regarding the PSA. In addition, a final meeting on the project was held at BNL on November 21-22, 2011, where BNL and KINS reviewers discussed their preliminary review findings with KHNP and KEPCO-E&C staffs. Additional information obtained during this final meeting was also used to inform the review findings of this final report. The review focused not only on the robustness of the APR+ design to withstand severe accidents, but also on the capability and acceptability of the Level 2 PSA in terms of level of detail and completeness. The Korean nuclear regulatory authorities will decide whether the PSA is acceptable and the BNL review team is providing its comments for KINS consideration. Section 2.0 provides the basis for the BNL review. Section 3.0 presents the review of each technical element of the PSA. Conclusions and a summary are presented in Section 4.0. Section 5.0 contains the references.

  1. Qualité de vie et vécu de la maladie, avant et après hystérectomie vaginale, chez les femmes admises au Centre Hospitalier Universitaire de Brazzaville

    PubMed Central

    Mbongo, Jean Alfred; Mouanga, Alain; Miabaou, Didace Massamba; Nzelie, Aya; Iloki, Léon Hervé

    2016-01-01

    Toute maladie est un mal en soi qu’il faut éradiquer car elle altère souvent de façon significative la qualité de la vie. L’hystérectomie vaginale est indiquée pour les patientes qui présentent certaines affections gynécologiques graves, elle est donc bénéfique mais, peut également avoir une répercussion néfaste sur la qualité de vie de la femme. Ainsi nous avons voulu explorer le vécu de la maladie et de l’hystérectomie vaginale (HV) des femmes avant et après l’intervention chirurgicale. Nous avons effectué une étude prospective qualitative, à recueil clinique sur une période de 12 mois; qui a concerné les femmes, ayant subi une hystérectomie vaginale. Celles n’ayant pas accepté de participer à l’étude, ou n’ayant pas de contact téléphonique n’ont pas été incluses. Pendant la maladie, le vécu des femmes a été: l’inconfort sexuel 26/40 (65%); les saignements génitaux 12/40 (30%); les douleurs pelviennes 13/40 (32,5%). En Post-opératoire, ont été noté les dyspareunies transitoires30/40 (75%) ; les céphalées secondaires à l’anesthésie 4/40 (10%). Le vécu psychologique a été dominé avant l’HV par la peur de la chirurgie chez toutes les patientes, les troubles du sommeil 38/40 (95%), l’angoisse 30 /40(75%), un sentiment de honte lié aux difficultés à accomplir l’acte sexuel en raison du prolapsus 26/40(65%) et/ ou en raison des saignements génitaux, dus au fibrome utérin 14/40(35%). Le sentiment de la perte de féminité était déclaré par 26/40 femmes porteuses de prolapsus utérin (65%), la modification de l’estime de soi 26/40 (65%). Ces appréciations subjectives ont été améliorées avec l’HV, contre balançant la perte de leur organe de reproduction. Aucune information n’a été donnée par les femmes à leurs proches et aux membres de la famille avant la chirurgie, traduisant ainsi leur sentiment de gène ou de honte. L’arrêt des symptômes a été observé dans tous les

  2. Hématome sous dural dorsal compliquant une anesthésie péridurale en chirurgie vasculaire

    PubMed Central

    Elahmadi, Brahim; Awab, Almahdi; El Moussaoui, Rachid; El Hijri, Ahmed; Azzouzi, Abderrahim; Alilou, Mustapha

    2014-01-01

    L'hématome péri médullaire est une complication rare, parfois invalidante de l'anesthésie péridurale. Il survient au décours d'une ponction difficile ou traumatique ou après une mauvaise gestion des anticoagulants. Son diagnostic est difficile parfois retardé. L'imagerie par résonance magnétique reste l'examen de choix. Le traitement est essentiellement chirurgical. Le pronostic dépend de l'importance de l'hématome et des lésions sous jacentes. Nous rapportons l'observation d'un hématome sous dural dorsal, compliquant une anesthésie péridurale en postopératoire d'un pontage aorto-bi fémoral, pour anévrysme de l'aorte abdominal sous rénale. PMID:25426189

  3. Anesthésie d’un greffé cardiaque en chirurgie non cardiaque: à propos d’un cas clinique et revue de la littérature

    PubMed Central

    Nassirou, Oumarou Mahamane Mamane; Jaafari, Abdelhamid; Chlouchi, Abdellatif; Bensghir, Mustapha; Haimeur, Charki

    2016-01-01

    Le nombre et la durée de survie des patients transplantés cardiaque sont en augmentation. Une partie de ces patients se présentent régulièrement pour une chirurgie générale en dehors de la transplantation cardiaque. L’anesthésie chez ces patients peut être difficile en raison des particularités physiologiques du cœur dénervé et de la gestion du traitement immunosuppresseur avec le risque de rejet et d’infection. Nous discutons la prise en charge anesthésique à travers un cas d’un patient âgé de 60 ans transplanté cardiaque devant subir une chirurgie de cure d’éventration abdominale et une revue de la littérature. PMID:28154639

  4. 15 CFR 782.2 - Persons responsible for submitting reports required under the APR.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... reports required under the APR. 782.2 Section 782.2 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE ADDITIONAL... responsible for submitting reports required under the APR. The owner, operator, or senior management official...

  5. Analyse Pharmaceutique de la prescription des antibiotiques au service des brules et chirurgie plastique de l'Hopital Militaire d'Instruction Mohammed V, Maroc

    PubMed Central

    Benziane, H.; Karfo, R.; Siah, S.; Taoufik, J.

    2011-01-01

    Summary L'infection est longtemps restée la principale cause de mortalité chez le brûlé grave. Ce travail a pour but d'évaluer la prescription des antibiotiques dans notre Service des Brûlés et Chirurgie Plastique, au regard du dossier d'autorisation de mise sur le marché (Résumé des caractéristiques du produit). Tous les patients sous antibiothérapie, au Service des Brûlés et Chirurgie Plastique de l'Hôpital Militaire d'Instruction Mohammed V de Rabat, Maroc, durant la période janvier 2008/mai 2009, ont été inclus. Il s'agit d'une étude rétrospective qui a analysé 41 dossiers de patients. Les antibiotiques utilisés par le service appartiennent à différentes familles. Les plus utilisés sont les bêta-lactamines (65%), glycopeptides (10,5%), aminosides (9%), quinolones (7%) et colistine (4,3%), avec 4,2% pour les autres classes d'antibiotiques (métronidazole 500 mg en perfusion, fluconazole injectable 100 mg/50 ml, rifampicine 600 mg en perfusion, sulfadiazine argentique crème, acide fusidique 2% crème, etc.); 70% des prescriptions sont non documentées. La voie injectable est prépondérante (89%). En tout, 227 ordonnances nominatives d'antibiothérapie ont été analysées: la posologie et les contre-indications ont été respectées par rapport à l'autorisation de mise sur le marché. Trois cas d'interactions médicamenteuses ont été relevés (fluconazole-rifampicine, fluconazole-Saccharomyces boulardii, amikacine-vancomycine). Ce constat montre l'importance de l'analyse pharmaceutique des prescriptions des antibiotiques dans un service utilisant des antibiotiques de la réserve hospitalière, donc actifs mais très toxiques. PMID:22396670

  6. Evaluation de la formation des résidents en chirurgie générale et digestive en Tunisie

    PubMed Central

    Mahmoudi, Ammar; Noomen, Faouzi; Nasr, Mohamed; Zouari, Khadija; Hamdi, Abdelaziz

    2015-01-01

    Introduction De nombreux moyens sont mis à disposition des résidents en chirurgie générale et digestive pour assurer leur formation théorique et pratique. Cependant, le niveau d'utilisation de ces différents outils et leur impact sur la formation des résidents n'ont jamais été évalués. L'objectif de notre étude était d’étudier l’état des lieux des moyens de formation utilisés par les résidents pour évaluer leurs degrés de satisfaction et leurs propositions en vue d'améliorer leur formation. Méthodes Un questionnaire anonyme a été distribué aux résidents de chirurgie générale et digestive de l'année 2012-2013. Ce questionnaire portait sur les caractéristiques démographiques, les ressources pédagogiques, ainsi que le cursus médical et universitaire. Une évaluation de la formation ainsi qu'un recueil des propositions faites en vue d'améliorer leurs formations étaient réalisées. Résultats Cinquante résidents sur 83 ont répondu au questionnaire. L'orientation de carrière la plus fréquente était l'hospitalo-universitaire dans 70% des cas. La pratique quotidienne et l'internet étaient les deux ressources pédagogiques les plus utilisées. La formation chirurgicale était jugée satisfaisante par seulement 10% des répondants. Parmi l'ensemble des propositions faites, l'apprentissage sur simulateur chirurgical, l'existence d'un ouvrage national de référence, et l'institution d'un tutorat par un chirurgien senior recueillaient plus de 80% d'avis favorable. Conclusion La majorité des résidents jugent leur formation non satisfaisante. Une meilleure information sur les ressources déjà existantes, un renforcement du compagnonnage et un accès plus large à un apprentissage sur simulateur chirurgical permettraient de diminuer ce sentiment d'insatisfaction. PMID:26587174

  7. Fuel assembly design for APR1400 with low CBC

    NASA Astrophysics Data System (ADS)

    Hah, Chang Joo

    2015-04-01

    APR 1400 is a PWR (Pressurized Water Reactor) with rated power of 3983 MWth and 241 assemblies. Recently, demand for extremely longer cycle up to 24 months is increasing with challenge of higher critical boron concentration (CBC). In this paper, assembly design method of selecting Gd-rods is introduced to reduce CBC. The purpose of the method is to lower the critical boron concentration of the preliminary core loading pattern (PLP), and consequently to achieve more negative or less positive moderator temperature coefficient (MTC). In this method, both the ratio of the number of low-Gd rod to the number of high-Gd rod (r) and assembly average Gd wt% (w) are the decision variables. The target function is the amount of soluble boron concentration reduction, which can be converted to ΔkTARGET. A set of new designed fuel assembly satisfies an objective function, min [f =∑i (ΔkF A-Δki ) ] , and enables a final loading pattern to reach a target CBC. The constraints required to determine a set of Δk are physically realizable pair, (r,w), and the sum of Δk of new designed assemblies as close to ΔkTARGET as possible. New Gd-bearing assemblies selected based on valid pairs of (r,w) are replaced with existing assemblies in a PLP. This design methodology is applied to Shin-Kori Unit 3 Cycle 1 used as a reference model. CASMO-3/MASTER code is used for depletion calculation. CASMO-3/MASTER calculations with new designed assemblies produce lower CBC than the expected CBC, proving that the proposed method works successful.

  8. Fuel assembly design for APR1400 with low CBC

    SciTech Connect

    Hah, Chang Joo

    2015-04-29

    APR 1400 is a PWR (Pressurized Water Reactor) with rated power of 3983 MWth and 241 assemblies. Recently, demand for extremely longer cycle up to 24 months is increasing with challenge of higher critical boron concentration (CBC). In this paper, assembly design method of selecting Gd-rods is introduced to reduce CBC. The purpose of the method is to lower the critical boron concentration of the preliminary core loading pattern (PLP), and consequently to achieve more negative or less positive moderator temperature coefficient (MTC). In this method, both the ratio of the number of low-Gd rod to the number of high-Gd rod (r) and assembly average Gd wt% (w) are the decision variables. The target function is the amount of soluble boron concentration reduction, which can be converted to Δk{sub TARGET}. A set of new designed fuel assembly satisfies an objective function, min [f=∑{sub i}(Δk{sub FA}−Δk{sub i})], and enables a final loading pattern to reach a target CBC. The constraints required to determine a set of Δk are physically realizable pair, (r,w), and the sum of Δk of new designed assemblies as close to Δk{sub TARGET} as possible. New Gd-bearing assemblies selected based on valid pairs of (r,w) are replaced with existing assemblies in a PLP. This design methodology is applied to Shin-Kori Unit 3 Cycle 1 used as a reference model. CASMO-3/MASTER code is used for depletion calculation. CASMO-3/MASTER calculations with new designed assemblies produce lower CBC than the expected CBC, proving that the proposed method works successful.

  9. 48 CFR 1552.235-76 - Treatment of Confidential Business Information (APR 1996).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...)(APR 1996) (a) The Project Officer (PO) or his/her designee, after a written determination by the... General Counsel for Information Law or his/her designee; and (iii) return the CBI to the PO or...

  10. 15 CFR 782.1 - Overview of reporting requirements under the APR.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE ADDITIONAL PROTOCOL... (see § 782.5 of the APR). In addition, forms may be downloaded from the Internet at http://www.ap.gov....

  11. 15 CFR 782.5 - Where to obtain APR report forms.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE ADDITIONAL PROTOCOL REGULATIONS GENERAL... forms required by the APR may be downloaded from the Internet at http://www.ap.gov. You also may...

  12. 15 CFR 782.1 - Overview of reporting requirements under the APR.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE ADDITIONAL PROTOCOL... (see § 782.5 of the APR). In addition, forms may be downloaded from the Internet at http://www.ap.gov....

  13. 15 CFR 782.5 - Where to obtain APR report forms.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE ADDITIONAL PROTOCOL REGULATIONS GENERAL... forms required by the APR may be downloaded from the Internet at http://www.ap.gov. You also may...

  14. 15 CFR 782.5 - Where to obtain APR report forms.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE ADDITIONAL PROTOCOL REGULATIONS GENERAL... forms required by the APR may be downloaded from the Internet at http://www.ap.gov. You also may...

  15. 15 CFR 782.5 - Where to obtain APR report forms.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE ADDITIONAL PROTOCOL REGULATIONS GENERAL... forms required by the APR may be downloaded from the Internet at http://www.ap.gov. You also may...

  16. 15 CFR 782.1 - Overview of reporting requirements under the APR.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE ADDITIONAL PROTOCOL... (see § 782.5 of the APR). In addition, forms may be downloaded from the Internet at http://www.ap.gov....

  17. 15 CFR 782.1 - Overview of reporting requirements under the APR.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE ADDITIONAL PROTOCOL... (see § 782.5 of the APR). In addition, forms may be downloaded from the Internet at http://www.ap.gov....

  18. 15 CFR 782.1 - Overview of reporting requirements under the APR.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE ADDITIONAL PROTOCOL... (see § 782.5 of the APR). In addition, forms may be downloaded from the Internet at http://www.ap.gov....

  19. 15 CFR 782.5 - Where to obtain APR report forms.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE ADDITIONAL PROTOCOL REGULATIONS GENERAL... forms required by the APR may be downloaded from the Internet at http://www.ap.gov. You also may...

  20. 86. Neg. No. F64, Apr 13, 1930, INTERIORASSEMBLY BUILDING, BODY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    86. Neg. No. F-64, Apr 13, 1930, INTERIOR-ASSEMBLY BUILDING, BODY STORAGE CONVEYOR - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  1. 79. Neg. No. F61A, Apr 13, 1930, INTERIORASSEMBLY BUILDING, BODY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    79. Neg. No. F-61A, Apr 13, 1930, INTERIOR-ASSEMBLY BUILDING, BODY CONSTRUCTION - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  2. 85. Neg. No. F51, Apr 13, 1930, INTERIORASSEMBLY BUILDING, BODY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    85. Neg. No. F-51, Apr 13, 1930, INTERIOR-ASSEMBLY BUILDING, BODY AND CUSHION LINE - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  3. 53. Neg. No. F69, Apr 21, 1930, EXTERIOROFFICE BUILDING, WEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    53. Neg. No. F-69, Apr 21, 1930, EXTERIOR-OFFICE BUILDING, WEST (FRONT) AND NORTH SIDES, OPENING DAY - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  4. 82. Neg. No. F66A, Apr 13, 1930, INTERIORASSEMBLY BUILDING, TRIM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    82. Neg. No. F-66A, Apr 13, 1930, INTERIOR-ASSEMBLY BUILDING, TRIM LINE AND GLASS DEPARTMENTS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  5. 83. Neg. No. F53, Apr 13, 1930, INTERIORASSEMBLY BUILDING, BACK ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    83. Neg. No. F-53, Apr 13, 1930, INTERIOR-ASSEMBLY BUILDING, BACK TRIM LINE - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  6. 90. Neg. No. F59A, Apr 13, 1930, INTERIORASSEMBLY BUILDING, CHASSIS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    90. Neg. No. F-59A, Apr 13, 1930, INTERIOR-ASSEMBLY BUILDING, CHASSIS LINE, LOOKING SOUTH - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  7. Expression and mechanism of regulation of PP2A/Pr65 in ameloblastoma.

    PubMed

    Gao, Xiuqiu; Wang, Guannan; Zhang, Yun-Kai; Zhong, Ming

    2014-06-01

    This study aimed to investigate the expression of PP2A/PR65 protein in ameloblastoma and the molecular mechanisms underlying the regulation of PP2A/PR65. The association between PP2A/PR65 and the clinicopathological characteristics of tumor specimens in ameloblastoma were to provide a theoretical basis for the diagnosis, therapy and prognosis of ameloblastoma. Streptavidin-peroxidase (S-P) immunohistochemical staining was used to detect PP2A/Pr65 expression changes in a total of 68 cases of ameloblastoma, six ameloblastic carcinomas, 21 squamous cell carcinomas and seven normal oral mucosas. Western blot was used to analyze PP2A/PR65 protein expression in 15 cases of ameloblastoma and three cases of normal oral mucosa. Of the 68 cases analyzed, four cases were negative, 25 cases were weakly positive, 20 cases were moderately positive and 19 cases were strongly positive. In six cases of ameloblastic carcinoma, three cases were weak positive, one case was positive, two cases were strongly positive and none were negative. In 21 cases of squamous cell carcinomas, three cases were negative, 17 cases were weakly positive, one case was moderately positive and none were strongly positive. Western blot analysis showed that, PP2A/Pr65 protein expression was lower in ameloblastoma tissue compared with normal oral mucosa. Reduced expression of PP2A/PR65 in ameloblastoma compared with normal oral mucosa indicates that PP2A/PR65 is involved in the occurrence and development of ameloblastoma. Copyright © 2013 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved.

  8. Reliability enhancement of APR + diverse protection system regarding common cause failures

    SciTech Connect

    Oh, Y. G.; Kim, Y. M.; Yim, H. S.; Lee, S. J.

    2012-07-01

    The Advanced Power Reactor Plus (APR +) nuclear power plant design has been developed on the basis of the APR1400 (Advanced Power Reactor 1400 MWe) to further enhance safety and economics. For the mitigation of Anticipated Transients Without Scram (ATWS) as well as Common Cause Failures (CCF) within the Plant Protection System (PPS) and the Emergency Safety Feature - Component Control System (ESF-CCS), several design improvement features have been implemented for the Diverse Protection System (DPS) of the APR + plant. As compared to the APR1400 DPS design, the APR + DPS has been designed to provide the Safety Injection Actuation Signal (SIAS) considering a large break LOCA accident concurrent with the CCF. Additionally several design improvement features, such as channel structure with redundant processing modules, and changes of system communication methods and auto-system test methods, are introduced to enhance the functional reliability of the DPS. Therefore, it is expected that the APR + DPS can provide an enhanced safety and reliability regarding possible CCF in the safety-grade I and C systems as well as the DPS itself. (authors)

  9. APR: A geographic information system based primary router for underground residential distribution design

    SciTech Connect

    Yeh, E.C.; Sumic, Z. |; Venkata, S.S.

    1995-02-01

    This paper presents an automated tool for optimizing the routing of primary cables in underground residential distribution systems (URD). Although initially developed as one of the modules in Puget Sound Power and Light Co.`s automated electrical plant design program, Automated Primary Router (APR) can also be used in standalone mode. APR, implemented in a Geographic Information System (GIS)-based environment, is capable of efficiently accessing and manipulating geographically referenced data from a facilities management system database. It also provides a full-fledged Graphic User Interface, along with on-line visualization and accurate cost estimation to facilitate the design process. APR employs a heuristic search algorithm to find the best primary cable routes either for new residential developments, or for existing URD systems as part of the ongoing cable replacement program. Based on the test results, APR shows significant stability and efficiency in finding the optimal solution for primary cable routing. With this performance, APR can help distribution engineers improve the quality of URD design, producing standardized and economically justifiable primary cable routes. Because geographically referenced design data are digitally stored in the GIS database, APR further increases the reusability and accessibility of the URD design information.

  10. APR: A geographic information system based primary router for underground residential distribution design

    SciTech Connect

    Yeh, E.C.; Sumic, Z. |; Venkata, S.S.

    1994-12-31

    This paper presents an automated tool for optimizing the routing of primary cables in underground residential distribution systems (URD). Although initially developed as on of the modules in Puget Sound Power and Light Co.`s automated electrical plant design program, Automated Primary Router (APR) can also be used in standalone mode. APR, implemented in a Geographic Information System (GIS)-based environment, is capable of efficiently accessing and manipulating geographically referenced data from a facilities management system database. It also provides a full-fledged Graphic User Interface, along with on-line visualization and accurate cost estimation to facilitate the design process. APR employs a heuristic search algorithm to find the best primary cable routes whether for new residential developments, or for existing URD systems as part of the ongoing cable replacement program. Based on the test results, APR shows significant stability and efficiency in finding the optimal solution for primary cable routing. With this performance, APR can help distribution engineers improve the quality of URD design, producing standardized and economically justifiable primary cable routes. Because geographically referenced design data are digitally stored in the GIS database, APR further increases the reusability and accessibility of the URD design information.

  11. Intérêt de la scintigraphie lymphatique et place de la chirurgie dans les chylothorax congénitaux

    PubMed Central

    Methlouthi, Jihène; Mahdhaoui, Nabiha; Bellalah, Manel; Selsabil, Nouir; Hedia, Ayache; Sfar, Raja; Essabah, Habib; Abdellatif, Nouri; Sonia, Nouri; Hassen, Seboui

    2016-01-01

    Le chylothorax est défini par l'accumulation du liquide lymphatique dans la cavité pleurale. Il existe 3 catégories distinctes chez le nouveau-né: les chylothorax congénitaux (CC), les chylothorax malformatifs ou syndromiques (CM) et les chylothorax post-opératoires (CO). Bien que rare, le chylothorax représente la cause la plus fréquente des épanchements pleuraux en période néonatale. Son diagnostic positif est facile par analyse du liquide pleural, mais son mécanisme et surtout l'intégrité du canal thoracique et ses collatérales est parfois difficile à préciser. La lymphoscintigraphie représente l'examen de choix dans le diagnostic etipathogénique. Ce moyen de diagnostic peut être couplé, si possible, au SPECT-CT (single photon emission tomography/computed tomography) permettant de donner des renseignements plus précis, notamment sur le plan anatomique. Sa prise en charge repose sur le drainage du liquide pleural, la suppression des graisses alimentaires et la nutrition parentérale. Le recours à la chirurgie est préconisé devant l'échec du traitement médical. Nous rapportons l'observation d'un nouveau-né porteur d'un chylothorax unilatéral, n'ayant pas répondu au traitement médical. La lymphoscintigraphie avait permis de diagnostiquer le mécanisme étiopathogénique et par conséquent, de guider le traitement chirurgical. PMID:28154676

  12. Examination of uncertainty in late reflood phase behavior of APR1400 LBLOCA

    SciTech Connect

    Sang Won Lee; Han Gon Kim; Seung Jong Oh; Sang Yong Lee

    2004-07-01

    APR1400 is an evolutionary PWR developed in Korea. The ECCS of APR1400 has been improved by adopting 4 safety injection pumps and fluidic devices in safety injection tanks. Also, APR1400 adopted direct vessel injection (DVI) for its ECCS injection: safety injection water is injected into the reactor vessel downcomer directly. The ECCS performance of APR1400 during the double-ended cold leg break LOCA, specially during the late reflood phase, is examined with the KEPRI Realistic Evaluation Methodologies (KREM). The applicability of KREM to the prediction of APR1400 specific thermal hydraulic phenomena in downcomer during the LBLOCA is examined first and the preliminary best estimate analysis is performed for the double-ended cold leg break LOCA. The analysis results show that there is no degradation of core coolability and reheating phenomena during the late reflood phase. All fuel rods are quenched in the early reflood phase during the fluidic devices are active, which shows the effectiveness of the fluidic devices in mitigating the LBLOCA. (authors)

  13. Assistant Personal Robot (APR): Conception and Application of a Tele-Operated Assisted Living Robot.

    PubMed

    Clotet, Eduard; Martínez, Dani; Moreno, Javier; Tresanchez, Marcel; Palacín, Jordi

    2016-04-28

    This paper presents the technical description, mechanical design, electronic components, software implementation and possible applications of a tele-operated mobile robot designed as an assisted living tool. This robotic concept has been named Assistant Personal Robot (or APR for short) and has been designed as a remotely telecontrolled robotic platform built to provide social and assistive services to elderly people and those with impaired mobility. The APR features a fast high-mobility motion system adapted for tele-operation in plain indoor areas, which incorporates a high-priority collision avoidance procedure. This paper presents the mechanical architecture, electrical fundaments and software implementation required in order to develop the main functionalities of an assistive robot. The APR uses a tablet in order to implement the basic peer-to-peer videoconference and tele-operation control combined with a tactile graphic user interface. The paper also presents the development of some applications proposed in the framework of an assisted living robot.

  14. Risk-adjusting acute myocardial infarction mortality: are APR-DRGs the right tool?

    PubMed Central

    Romano, P. S.; Chan, B. K.

    2000-01-01

    OBJECTIVE: To determine if a widely used proprietary risk-adjustment system, APR-DRGs, misadjusts for severity of illness and misclassifies provider performance. DATA SOURCES: (1) Discharge abstracts for 116,174 noninstitutionalized adults with acute myocardial infarction (AMI) admitted to nonfederal California hospitals in 1991-1993; (2) inpatient medical records for a stratified probability sample of 974 patients with AMIs admitted to 30 California hospitals between July 31, 1990 and May 31, 1991. STUDY DESIGN: Using the 1991-1993 data set, we evaluated the predictive performance of APR-DRGs Version 12. Using the 1990/1991 validation sample, we assessed the effect of assigning APR-DRGs based on different sources of ICD-9-CM data. DATA COLLECTION/EXTRACTION METHODS: Trained, blinded coders reabstracted all ICD-9-CM diagnoses and procedures, and established the timing of each diagnosis. APR-DRG Risk of Mortality and Severity of Illness classes were assigned based on (1) all hospital-reported diagnoses, (2) all reabstracted diagnoses, and (3) reabstracted diagnoses present at admission. The outcome variables were 30-day mortality in the 1991-1993 data set and 30-day inpatient mortality in the 1990/1991 validation sample. PRINCIPAL FINDINGS: The APR-DRG Risk of Mortality class was a strong predictor of death (c = .831-.847), but was further enhanced by adding age and sex. Reabstracting diagnoses improved the apparent performance of APR-DRGs (c = .93 versus c = .87), while using only the diagnoses present at admission decreased apparent performance (c = .74). Reabstracting diagnoses had less effect on hospitals' expected mortality rates (r = .83-.85) than using diagnoses present at admission instead of all reabstracted diagnoses (r = .72-.77). There was fair agreement in classifying hospital performance based on these three sets of diagnostic data (K = 0.35-0.38). CONCUSIONS: The APR-DRG Risk of Mortality system is a powerful risk-adjustment tool, largely because it

  15. Molecular genetic analysis of Dichelobacter nodosus proteases AprV2/B2, AprV5/B5 and BprV/B in clinical material from European sheep flocks.

    PubMed

    Stäuble, Anna; Steiner, Adrian; Normand, Lea; Kuhnert, Peter; Frey, Joachim

    2014-01-10

    Dichelobacter nodosus, the etiological agent of ovine footrot, exists both as virulent and as benign strains, which differ in virulence mainly due to subtle differences in the three subtilisin-like proteases AprV2, AprV5 and BprV found in virulent, and AprB2, AprB5 and BprB in benign strains of D. nodosus. Our objective was a molecular genetic epidemiological analysis of the genes of these proteases by direct sequence analysis from clinical material of sheep from herds with and without history of footrot from 4 different European countries. The data reveal the two proteases known as virulent AprV2 and benign AprB2 to correlate fully to the clinical status of the individuals or the footrot history of the herd. In samples taken from affected herds, the aprV2 gene was found as a single allele whereas in samples from unaffected herds several alleles with minor modifications of the aprB2 gene were detected. The different alleles of aprB2 were related to the herds. The aprV5 and aprB5 genes were found in the form of several alleles scattered without distinction between affected and non-affected herds. However, all different alleles of aprV5 and aprB5 encode the same amino acid sequences, indicating the existence of a single protease isoenzyme 5 in both benign and virulent strains. The genes of the basic proteases BprV and BprB also exist as various alleles. However, differences found in samples from affected versus non-affected herds do not reflect the currently known epitopes that are attributed to differences in biochemical activity. The data of the study confirm the prominent role of AprV2 in the virulence of D. nodosus and shed a new light on the presence of the other protease genes and their allelic variants in clinical samples.

  16. Anti-inflammatory and anti-proliferative effect of herbal medicines (APR) in RAW264.7 cells

    PubMed Central

    CHOI, HAN-SEOK; SEO, HYE SOOK; KIM, SOON RE; CHOI, YOUN KYUNG; SHIN, YONG-CHEOL; KO, SEONG-GYU

    2014-01-01

    The objective of the present study was to analyze the effect of a mixture of medicinal plants [Angelica gigas Nakai, Panax ginseng and Rhus verniciflua Stokes (APR)] on lipopolysaccharide (LPS)-induced inflammatory responses in the murine macrophage cell line RAW264.7. Cells were treated with APR and LPS at various concentrations and indicated times. WST assay, trypan blue assay and quantification of activated cells demonstrated that APR suppressed cell proliferation in a dose-dependent manner. APR induced G1 cell cycle arrest and inhibited the LPS-induced phosphorylation of protein kinase B (AKT), extracellular signal-regulated kinase (ERK), mitogen-activated protein kinase (p38) and necrosis factor κB (NF-κB). APR also suppressed nitric oxide synthase isoform (iNOS) and prostaglandin endoperoxide synthase 2 (Cox-2) messenger ribonucleic acid (mRNA) expression induced by LPS. Furthermore, APR decreased LPS-induced intracellular reactive oxygen species (ROS) levels, mitochondrial membrane potential, as well as induced PARP and caspase-3 cleavage, suggesting that APR causes apoptosis. In conclusion, the present study indicated that APR may be advantageous in treating inflammatory disease. PMID:24626965

  17. 23. "GAFFTC 20 APR 60, H65A F106A; ESCAPE SYSTEM RUN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. "G-AFFTC 20 APR 60, H-6-5A F-106A; ESCAPE SYSTEM RUN 5A." Testing the ejection system on a Convair sled. - Edwards Air Force Base, South Base Sled Track, Edwards Air Force Base, North of Avenue B, between 100th & 140th Streets East, Lancaster, Los Angeles County, CA

  18. 15 CFR 781.1 - Definitions of terms used in the Additional Protocol Regulations (APR).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Regulatory Commission. Nuclear fuel cycle-related research and development. Those activities that are...) of the APR for nuclear fuel cycle-related activities subject to these reporting requirements). Reporting Code. A unique identification used for identifying a location where one or more nuclear fuel cycle...

  19. 15 CFR 781.1 - Definitions of terms used in the Additional Protocol Regulations (APR).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Regulatory Commission. Nuclear fuel cycle-related research and development. Those activities that are...) of the APR for nuclear fuel cycle-related activities subject to these reporting requirements). Reporting Code. A unique identification used for identifying a location where one or more nuclear fuel cycle...

  20. 15 CFR 781.1 - Definitions of terms used in the Additional Protocol Regulations (APR).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Regulatory Commission. Nuclear fuel cycle-related research and development. Those activities that are...) of the APR for nuclear fuel cycle-related activities subject to these reporting requirements). Reporting Code. A unique identification used for identifying a location where one or more nuclear fuel cycle...

  1. 15 CFR 781.1 - Definitions of terms used in the Additional Protocol Regulations (APR).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Regulatory Commission. Nuclear fuel cycle-related research and development. Those activities that are...) of the APR for nuclear fuel cycle-related activities subject to these reporting requirements). Reporting Code. A unique identification used for identifying a location where one or more nuclear fuel cycle...

  2. 15 CFR 781.1 - Definitions of terms used in the Additional Protocol Regulations (APR).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Regulatory Commission. Nuclear fuel cycle-related research and development. Those activities that are...) of the APR for nuclear fuel cycle-related activities subject to these reporting requirements). Reporting Code. A unique identification used for identifying a location where one or more nuclear fuel cycle...

  3. 54. Neg. No. F110P, Apr 24, 1931, EXTERIORPRESSED STEEL BUILDING, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    54. Neg. No. F-110P, Apr 24, 1931, EXTERIOR-PRESSED STEEL BUILDING, NORTH AND EAST SIDES, WAREHOUSE IN BACKGROUND, RAILROAD SPUR IN FOREGROUND, BONDERITE TANK AT LEFT - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  4. Using a Classroom Response System to Improve Multiple-Choice Performance in AP[R] Physics

    ERIC Educational Resources Information Center

    Bertrand, Peggy

    2009-01-01

    Participation in rigorous high school courses such as Advanced Placement (AP[R]) Physics increases the likelihood of college success, especially for students who are traditionally underserved. Tackling difficult multiple-choice exams should be part of any AP program because well-constructed multiple-choice questions, such as those on AP exams and…

  5. Privacy Impact Assessment for the TRIO Programs Annual Performance Report (APR) System

    ERIC Educational Resources Information Center

    US Department of Education, 2008

    2008-01-01

    The TRIO Programs Annual Performance Report (APR) System collects individual student records on individuals served by the following Federal TRIO Programs: Upward Bound (which includes regular Upward Bound (UB), Upward Bound Math-Science (UBMS), and Veterans Upward Bound (VUB)); Student Support Services (SSS); and the Ronald E. McNair Post…

  6. Student Access to Advanced Placement[R] (AP[R]) Coursework: Principals' Beliefs and Practices

    ERIC Educational Resources Information Center

    Wood, Steven M.

    2010-01-01

    Advanced Placement[R] (AP[R]) courses provide high school students an opportunity to be exposed to the rigors of college while they are still in high school. Since school policies play a role in the opportunities for students to pursue these courses, educational leaders must be aware of the ways in which their personal beliefs and school practices…

  7. 14 CFR Appendix H to Part 23 - Installation of An Automatic Power Reserve (APR) System

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... failure, transmit signals, actuate fuel controls or power levers on operating engines, including power... power lever position; and (c) That shown to be free of hazardous engine response characteristics when...; (3) Prevent deactivation of the APR by manual adjustment of the power levers following an engine...

  8. 14 CFR Appendix H to Part 23 - Installation of An Automatic Power Reserve (APR) System

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... failure, transmit signals, actuate fuel controls or power levers on operating engines, including power... power lever position; and (c) That shown to be free of hazardous engine response characteristics when...; (3) Prevent deactivation of the APR by manual adjustment of the power levers following an engine...

  9. 14 CFR Appendix H to Part 23 - Installation of An Automatic Power Reserve (APR) System

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... failure, transmit signals, actuate fuel controls or power levers on operating engines, including power... power lever position; and (c) That shown to be free of hazardous engine response characteristics when...; (3) Prevent deactivation of the APR by manual adjustment of the power levers following an engine...

  10. 14 CFR Appendix H to Part 23 - Installation of An Automatic Power Reserve (APR) System

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... failure, transmit signals, actuate fuel controls or power levers on operating engines, including power... power lever position; and (c) That shown to be free of hazardous engine response characteristics when...; (3) Prevent deactivation of the APR by manual adjustment of the power levers following an engine...

  11. 14 CFR Appendix H to Part 23 - Installation of An Automatic Power Reserve (APR) System

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... failure, transmit signals, actuate fuel controls or power levers on operating engines, including power... power lever position; and (c) That shown to be free of hazardous engine response characteristics when...; (3) Prevent deactivation of the APR by manual adjustment of the power levers following an engine...

  12. Categorizing Ice Crystals Using Airborne APR-2 and HVPS Observations during GCPEx

    NASA Astrophysics Data System (ADS)

    Martinez, M., III; Bennartz, R.; Turk, F. J.; Tanelli, S.; Sy, O. O.; Bansemer, A.; Kuo, K. S.

    2014-12-01

    Current and planned millimeter-wave passive and active satellite sensors are proposed for future low Earth-orbiting satellite platforms. For accurate modeling and sensor simulation of ice clouds at these wavelengths, realistic particle shapes and size distributions (PSD) need to be used. During the Jan-Feb 2012 Global Precipitation Measurement (GPM) Cold Season Precipitation Experiment (GCPEx) near Toronto, Canada, the Jet Propulsion Laboratory (JPL) dual-frequency (Ku/Ka-band) Airborne Precipitation Radar (APR-2) flew onboard the NASA DC-8 aircraft. Coordinated flights were carried out with the Univ. of North Dakota Citation aircraft carrying the High Volume Precipitation Spectrometer (HVPS-3), to collect cloud PSD and particle imagery. Selected flights enabled collection of coincident sampling volumes from the APR-2 and the HVPS. This unique dataset enables the scattering properties of the frozen hydrometeors to be modeled using the HVPS-provided particle distributions, and compared with APR-2 observations. The wide variety of fractal-like particle shapes measured in the HVPS data were separated into size bins and presented as 2 dimensional histograms with bins defined by Aspect (As) and Area (Ar) ratio. Individual histograms were previously characterized by the mean As and Ar values, ignoring the preferential linear trend between As and Ar visible for data points within most particle sizes. To facilitate the scattering models, we attempted to partition particles by shape within four size-invariant As and Ar categories. The four unique PSD, created by particle shape segregation, were then used to forward model the Ku and Ka- band radar reflectivities to locate the particle characteristics that provided the best agreement with actual APR-2 observations. In future work, these PSD will be used for passive microwave satellite sensor simulations of cold season precipitation and compared to actual satellite observations.

  13. Multiple Assets Position Determination in a 3-Dimensional Environment Using the APRS Protocol

    DTIC Science & Technology

    2007-09-01

    receiving end, demodulated data from the radio receiver is passed to the radio modem and is converted back to a digital data stream and decoded ...microcontroller parses the converts them into an APRS orwarded to the radio module nd a packet decoder on the a screen. Since it is only a us transmissions... decoded , the information is set to a layers component to be displayed. Below is an image representing various sources being plotted on World Wind

  14. The Alberta Pregnancy Outcomes and Nutrition (APrON) cohort study: rationale and methods.

    PubMed

    Kaplan, Bonnie J; Giesbrecht, Gerald F; Leung, Brenda M Y; Field, Catherine J; Dewey, Deborah; Bell, Rhonda C; Manca, Donna P; O'Beirne, Maeve; Johnston, David W; Pop, Victor J; Singhal, Nalini; Gagnon, Lisa; Bernier, Francois P; Eliasziw, Misha; McCargar, Linda J; Kooistra, Libbe; Farmer, Anna; Cantell, Marja; Goonewardene, Laki; Casey, Linda M; Letourneau, Nicole; Martin, Jonathan W

    2014-01-01

    The Alberta Pregnancy Outcomes and Nutrition (APrON) study is an ongoing prospective cohort study that recruits pregnant women early in pregnancy and, as of 2012, is following up their infants to 3 years of age. It has currently enrolled approximately 5000 Canadians (2000 pregnant women, their offspring and many of their partners). The primary aims of the APrON study were to determine the relationships between maternal nutrient intake and status, before, during and after gestation, and (1) maternal mood; (2) birth and obstetric outcomes; and (3) infant neurodevelopment. We have collected comprehensive maternal nutrition, anthropometric, biological and mental health data at multiple points in the pregnancy and the post-partum period, as well as obstetrical, birth, health and neurodevelopmental outcomes of these pregnancies. The study continues to follow the infants through to 36 months of age. The current report describes the study design and methods, and findings of some pilot work. The APrON study is a significant resource with opportunities for collaboration.

  15. Assistant Personal Robot (APR): Conception and Application of a Tele-Operated Assisted Living Robot

    PubMed Central

    Clotet, Eduard; Martínez, Dani; Moreno, Javier; Tresanchez, Marcel; Palacín, Jordi

    2016-01-01

    This paper presents the technical description, mechanical design, electronic components, software implementation and possible applications of a tele-operated mobile robot designed as an assisted living tool. This robotic concept has been named Assistant Personal Robot (or APR for short) and has been designed as a remotely telecontrolled robotic platform built to provide social and assistive services to elderly people and those with impaired mobility. The APR features a fast high-mobility motion system adapted for tele-operation in plain indoor areas, which incorporates a high-priority collision avoidance procedure. This paper presents the mechanical architecture, electrical fundaments and software implementation required in order to develop the main functionalities of an assistive robot. The APR uses a tablet in order to implement the basic peer-to-peer videoconference and tele-operation control combined with a tactile graphic user interface. The paper also presents the development of some applications proposed in the framework of an assisted living robot. PMID:27136552

  16. Subtilisin Sendai from alkalophilic Bacillus sp.: molecular and enzymatic properties of the enzyme and molecular cloning and characterization of the gene, aprS.

    PubMed

    Yamagata, Y; Isshiki, K; Ichishima, E

    1995-07-01

    We purified a new extracellular serine proteinase (designated subtilisin Sendai) from the culture broth of alkalophilic Bacillus sp. G-825-6, and its properties were characterized. Its optimum pH was at 10.0, when succinyl-L-leucyl-L-leucyl-L-valyl-L-tyrosyl-4-methylcoumaryl-7-amide (Suc-Leu-Leu-Val-Tyr-MCA) was used as a substrate. The substrate specificity of subtilisin Sendai was determined with oxidized insulin B-chain and fluorogenic peptidyl-MCA substrates. The isoelectric point of subtilisin Sendai was over 11.0. The molecular mass of the enzyme was estimated as 28,000 using sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The circular dichroism spectrum of the enzyme was measured, and we discuss the relationship between the secondary structure of the enzyme and alkaline stability at pH 12 in comparison with that of subtilisin NAT. The structural gene (aprS) was cloned and sequenced. The deduced amino acid sequence for the mature protein (269 amino acids) was preceded by a putative signal sequence of 27 residues and a putative pro-sequence of 86 amino acids. The homology of the primary structure for 13 subtilisins was compared. The catalytic triad (Asp32, His64, and Ser221 with the numbering of subtilisin BPN') and the amino acid sequences near these amino acid residues were well conserved. As a special feature, it was observed that there was an extensive number of negatively charged amino acids in the pro-region of subtilisin Sendai and alkaline subtilisins. This was different from those of subtilisin from neutrophiles.

  17. Les complications abdominales associées à la chirurgie cardiaque : à propos d'une expérience chirurgicale contemporaine et examen d'une population opérée sans circulation extracorporelle

    PubMed Central

    Poirier, Brigitte; Baillot, Richard; Bauset, Richard; Dagenais, François; Mathieu, Patrick; Simard, Serge; Dionne, Brigitte; Caouette, Manon; Hould, Frédéric-Simon; Doyle, Daniel; Poirier, Paul

    2003-01-01

    Introduction Pour évaluer l'incidence, les facteurs de risque et la morbidité associés aux complications gastro-intestinales (GI) suite à une chirurgie cardiaque avec ou sans circulation extra-corporelle (CEC), nous avons effectué une étude rétrospective de cohortes dans un hôpital universitaire. Méthodes 11 405 patients adultes répartis en 2 groupes : groupe A (de janvier 1992 à juin 1996, 4657 patients) et groupe B (de juillet 1996 à décembre 2000, 6748 patients). Résultats 134 patients (1,2 %) ont présenté 147 complications. Le pourcentage des événements GI fut identique pour les 2 groupes (groupe A, n = 59/4657 [1,2 %]; groupe B, n = 75/6748 [1,1 %]). Le groupe B était composé de patients plus âgés, obèses, diabétiques ayant une maladie vasculaire cérébrale et périphérique. Les complications les plus fréquentes sont associées à l'œsophage et l'estomac, n = 67/147 (45,5 %). Nous identifions à la suite 10 (6,8 %) cholécystites, 13 (8,8 %) pancréatites, 17 (11,6 %) atteintes ischémiques du grêle et du colon, 12 (8,2 %) colites pseudomembraneuses et 5 (3,4 %) diverticulites. L'ischémie mésentérique est responsable de 11 (37,9 %) des 29 décès; 293 patients ont subi une revascularisation myocardique à cœur battant. Cinq patients (1,7 %) ont présenté des complications GI dont trois avec ischémie viscérale. L'analyse multivariée démontre que l'insuffisance rénale, l'intubation prolongée et l'infection sont associées aux complications GI dans les deux groupes alors que le score de Parsonnet et l'accident vasculaire cérébral apparaissent prédictifs dans le second groupe. Conclusions Ces résultats démontent que le nombre de patients qui présentent des complications GI lors d'une chirurgie cardiaque n'augmente pas malgré le caractère sénescent et la co-morbidité. La chirurgie coronarienne pratiquée sans CEC ne semble pas diminuer l'incidence des complications GI. PMID:12812238

  18. Chirurgie coronaire isolée chez l’octogénaire : Résultats immédiats et analyse du taux de survie et de la qualité de vie à long terme

    PubMed Central

    Bach, Vincent; Tramaille, Sophie; Chavanon, Olivier; Durand, Michel; Noirclerc, Marianne; Vesin, Claire; Porcu, Paolo; Hacini, Rachid; Vanzetto, Gérald; Machecourt, Jacques

    2008-01-01

    HISTORIQUE : Près de trois millions d’octogénaires vivent en France, et ils sont nombreux à présenter une coronaropathie. Par ailleurs, l’espérance de vie à 80 ans semble encore importante. OBJECTIF : Évaluer les résultats d’une chirurgie coronaire chez ces patients. MÉTHODOLOGIE : Nous avons comparé 88 patients octogénaires consécutifs ayant subi un pontage aortocoronarien isolé entre 1996 et 2002 à 165 patients de 60 à 70 ans. Les deux groupes ont été appariés selon les principaux facteurs de risque. Nous avons pris contact avec les patients par téléphone et leur avons fait parvenir un questionnaire sur la qualité de vie. RÉSULTATS : La mortalité opératoire s’élevait à 2,3 % chez les octogénaires, par rapport à 1,2 % chez les 60 à 70 ans (P non significatif). Il y avait plus de bas débit, d’insuffisance rénale aiguë postopératoire et de transfusion chez les octogénaires. La survie à long terme (durée moyenne du suivi de 3,8 ans) était plus élevée chez les 60 à 70 ans : 89,7 % par rapport à 77,9 % (P=0,025). Nous avons constaté quatre facteurs de risque indépendants d’augmentation de la mortalité à long terme; âge, diabète, antécédents d’accident vasculaire cérébral et de transfusion sanguine postopératoire. Enfin, la survie à long terme des octogénaires opérés était significativement plus élevée que celle des octogénaires de la population générale de France, et leur qualité de vie était considérée comme satisfaisante. CONCLUSION : Pour des octogénaires sélectionnés, on peut proposer une chirurgie coronaire isolée, et les résultats à court et à long terme seront comparables à ceux d’une population plus jeune. PMID:18841258

  19. EURAPS at 20 years. A brief history of European Plastic Surgery from the Société Européenne de Chirurgie Structive to the European Association of Plastic Surgeons (EURAPS).

    PubMed

    Mazzola, Riccardo F; Kon, Moshe

    2010-06-01

    By the end of WWI, plastic surgery had reached unexpected heights. The high quality of the work done for soldiers with facial injuries and burns, either as an emergency or as a delayed procedure, demonstrated that this new discipline was honourable, worthwhile and socially crucial, thus deserving official recognition and independence. The establishment of new plastic surgery centres, scientific societies and specialised journals were the key to success for the achievement of this goal. In 1936, the Belgian Maurice Coelst (1894-1963) founded the Société Européenne de Chirurgie Structive, the first supranational society, with the aim of gathering once a year all those interested in this new branch of surgery and favouring confrontation of ideas by showing innovative clinical procedures. The very successful first Congress with a large international participation was held in Brussels, with Coelst as the president, the second in London, in 1937, organised by Kilner and the third in Milano, in 1938, arranged by Sanvenero Rosselli. Even live surgery was performed during the meetings. The beginning of the WWII stopped the Societé's activities, which were never resumed. In the late 1980s, when plastic surgery reached its zenith, the necessity was felt to create a new supranational society, different in its purpose from the existing European Section of IPRAS, later European Society of Plastic Reconstructive and Aesthetic Surgery (ESPRAS), an organisation where all the official European plastic surgery societies merged automatically. The aim was to promote the excellence of plastic surgery in Europe, to furnish an annual forum for the selection of the best scientific works presented at national societies and to stimulate research and education at a European level. Established in 1989, 53 years after the foundation of the Société Européenne de Chirurgie Structive, it was named the European Association of Plastic Surgeons (EURAPS). The first scientific meeting took place

  20. La Greffe de Peau dans le Traitement des Sequelles de la Main Brulee. A Propos de 152 Cas - Experience du Service de Chirurgie Plastique du Centre Hospitalier Universitaire Ibn-Sina, Rabat, Maroc

    PubMed Central

    El Mazouz, S.; Fejjal, N.; Hafidi, J.; Cherkab, L.; Mejjati, H.; Belfqih, R.; Gharib, N.; Abbassi, A.

    2010-01-01

    Summary La main est fréquemment exposée aux brûlures, entraînant des séquelles esthétiques et fonctionnelles. Le traitement de ces séquelles est surtout chirurgical et consiste en la greffe de peau, dont le type dépend de la localisation de la brûlure et du type des séquelles. Dans ce travail rétrospectif, nous rapportons une série de 152 cas de brûlures des mains colligés au service de chirurgie plastique du Centre Hospitalier Universitaire Ibn-Sina de Rabat sur une période de dix ans, allant de 1998 à 2007. Les indications thérapeutiques dépendent du type de séquelles et de la localisation de la brûlure. En tout, 97 patients ont bénéficié d'une greffe cutanée, dont 76% par greffe de peau totale, 21% par greffe de peau demi-épaisse et 3% par peau fine. Les séquelles des brûlures des mains posent un problème thérapeutique majeur, malgré la diversité des procédés chirurgicaux, d'où l'intérêt de la prévention. PMID:21991196

  1. Characterisation of the enzymatic properties of MpAPr1, an aspartic protease secreted by the wine yeast Metschnikowia pulcherrima.

    PubMed

    Theron, Louwrens Wiid; Bely, Marina; Divol, Benoit

    2017-08-01

    MpAPr1, encoding an acid protease from the wine yeast Metschnikowia pulcherrima IWBT Y1123, was previously isolated and shown to display potential activity against casein and grape proteins. However, its characterisation remained partial. MpAPr1 was cloned into the pGAPZαA vector and transformed into Komagataella pastoris X33 for heterologous expression. After verification of activity, the enzyme properties were characterised. Protease activity within the concentrated supernatant was retained over a pH range of 3.0 to 5.0 and between 10 °C and 50 °C. Optimal conditions for protease activity were found at 40 °C and pH 4.5. Activity was mostly unaffected by the presence of metal ions with the exception of Cu(2+) and Ni(2+) . Furthermore, proteolytic activity was retained in the presence of sugar and ethanol. pH and temperature conditions for MpAPr1 expression in K. pastoris were optimised. Purification was achieved by means of cation exchange chromatography and kinetic parameters (Km and Vmax ) were determined. MpAPr1 activity against grape proteins was confirmed, but the extent of the degradation was dependent on the nature of these proteins and the environmental conditions. Overall, the results suggest that MpAPr1 could be applied in food biotechnology processes such as winemaking. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  2. Crystallization of the C-terminal redox domain of the sulfur-assimilatory enzyme APR1 from Arabidopsis thaliana.

    PubMed

    Chen, Fang-Fang; Chang, Yu-Yung; Cho, Chao-Cheng; Hsu, Chun-Hua

    2014-09-01

    Plant-type APS reductase (APR), which catalyzes the reduction of activated sulfate to sulfite in plants, consists of a reductase domain and a C-terminal redox domain showing sequence homology to thioredoxin but possessing the activity of glutaredoxin. In order to understand the structural and biochemical properties of the redox domain of plant-type APS reductase, the C-terminal domain of APR1 (APR1C) from Arabidopsis thaliana was crystallized using the sitting-drop vapour-diffusion method. X-ray diffraction data were collected to a resolution of 2.70 Å on the SPXF beamline BL13B1 at the NSRRC, Taiwan. The crystals belonged to space group P43212 or P41212, with unit-cell parameters a = b = 58.2, c = 86.7 Å. With one molecule per asymmetric unit, the crystal volume per unit protein weight (VM) is 2.64 Å(3) Da(-1), which corresponds to a solvent content of approximately 53.49%. Further structure-based functional studies of APR1C would extend knowledge of the molecular mechanism and regulation of APR.

  3. Après-Coup in French Psychoanalysis: The Long Afterlife of Nachträglichkeit: The First Hundred Years, 1893 to 1993.

    PubMed

    House, Jonathan; Slotnick, Julie

    2015-10-01

    Après-coup finds its origins in Freud's earliest psychoanalytic writings, but it was only half a century ago that French psychoanalysts rediscovered, clarified, and developed the concept and so brought it recognition as an essential Freudian concept. Because the history of après-coup is embedded in the French reading of Freud, this article will give an account of that reading in relation to après-coup.

  4. The X-ray crystal structure of APR-B, an atypical adenosine 5'-phosphosulfate reductase from Physcomitrella patens.

    PubMed

    Stevenson, Clare E M; Hughes, Richard K; McManus, Michael T; Lawson, David M; Kopriva, Stanislav

    2013-11-15

    Sulfonucleotide reductases catalyse the first reductive step of sulfate assimilation. Their substrate specificities generally correlate with the requirement for a [Fe4S4] cluster, where adenosine 5'-phosphosulfate (APS) reductases possess a cluster and 3'-phosphoadenosine 5'-phosphosulfate reductases do not. The exception is the APR-B isoform of APS reductase from the moss Physcomitrella patens, which lacks a cluster. The crystal structure of APR-B, the first for a plant sulfonucleotide reductase, is consistent with a preference for APS. Structural conservation with bacterial APS reductase rules out a structural role for the cluster, but supports the contention that it enhances the activity of conventional APS reductases.

  5. New tools for NTD vaccines: A case study of quality control assays for product development of the human hookworm vaccine Na-APR-1M74.

    PubMed

    Pearson, Mark S; Jariwala, Amar R; Abbenante, Giovanni; Plieskatt, Jordan; Wilson, David; Bottazzi, Maria Elena; Hotez, Peter J; Keegan, Brian; Bethony, Jeffrey M; Loukas, Alex

    2015-01-01

    Na-APR-1(M74) is an aspartic protease that is rendered enzymatically inactive by site-directed mutagenesis and is a candidate antigen component in the Human Hookworm Vaccine. The mutant protease exerts vaccine efficacy by inducing antibodies that neutralize the enzymatic activity of wild type enzyme (Na-APR-1wt) in the gut of the hookworm, thereby depriving the worm of its ability to digest its blood meal. Previously, canines immunized with Na-APR-1(M74) and challenged with Ancylostoma caninum were partially protected against hookworm challenge infection, especially from the loss in hemoglobin observed in control canines and canine immunoglobulin (Ig) G raised against Na-APR-1 was shown to inhibit the enzymatic activity of Na-APR-1 wt in vitro, thereby providing proof of concept of Na-APR-1(M74) as a vaccine antigen. The mutated version, Na-APR-1(M74), was then expressed at the cGMP level using a Nicotiana benthamiana expression system (Fraunhofer, CMB, Delaware, MD), formulated with Alhydrogel®, and used to immunize mice in a dose-ranging study to explore the enzyme-neutralizing capacity of the resulting anti- Na-APR-1(M74) IgG. As little as 0.99 μg of recombinant Na-APR-1(M74) could induce anti Na-APR-1(M74) IgG in mice that were capable of inhibiting Na-APR-1w t-mediated digestion of a peptide substrate by 89%. In the absence of enzymatic activity of Na-APR-1(M74) as a surrogate marker of protein functionality, we developed an assay based on the binding of a quenched fluorescence-labeled inhibitor of aspartic proteases, BODIPY-FL pepstatin A (BDP). Binding of BDP in the active site of Na-APR-1 wt was demonstrated by inhibition of enzymatic activity, and competitive binding with unlabelled pepstatin A. BDP also bound to Na-APR-1(M74) which was assessed by fluorescence polarization, but with an ∼ 50-fold reduction in the dissociation constant. Taken together, these assays comprise a "toolbox" that could be useful for the analyses of Na-APR-1(M74) as it

  6. New tools for NTD vaccines: A case study of quality control assays for product development of the human hookworm vaccine Na-APR-1M74

    PubMed Central

    Pearson, Mark S; Jariwala, Amar R; Abbenante, Giovanni; Plieskatt, Jordan; Wilson, David; Bottazzi, Maria Elena; Hotez, Peter J; Keegan, Brian; Bethony, Jeffrey M; Loukas, Alex

    2015-01-01

    Na-APR-1M74 is an aspartic protease that is rendered enzymatically inactive by site-directed mutagenesis and is a candidate antigen component in the Human Hookworm Vaccine. The mutant protease exerts vaccine efficacy by inducing antibodies that neutralize the enzymatic activity of wild type enzyme (Na-APR-1wt) in the gut of the hookworm, thereby depriving the worm of its ability to digest its blood meal. Previously, canines immunized with Na-APR-1M74 and challenged with Ancylostoma caninum were partially protected against hookworm challenge infection, especially from the loss in hemoglobin observed in control canines and canine immunoglobulin (Ig) G raised against Na-APR-1 was shown to inhibit the enzymatic activity of Na-APR-1wt in vitro, thereby providing proof of concept of Na-APR-1M74 as a vaccine antigen. The mutated version, Na-APR-1M74, was then expressed at the cGMP level using a Nicotiana benthamiana expression system (Fraunhofer, CMB, Delaware, MD), formulated with Alhydrogel®, and used to immunize mice in a dose-ranging study to explore the enzyme-neutralizing capacity of the resulting anti- Na-APR-1M74 IgG. As little as 0.99 μg of recombinant Na-APR-1M74 could induce anti Na-APR-1M74 IgG in mice that were capable of inhibiting Na-APR-1wt-mediated digestion of a peptide substrate by 89%. In the absence of enzymatic activity of Na-APR-1M74 as a surrogate marker of protein functionality, we developed an assay based on the binding of a quenched fluorescence-labeled inhibitor of aspartic proteases, BODIPY-FL pepstatin A (BDP). Binding of BDP in the active site of Na-APR-1wt was demonstrated by inhibition of enzymatic activity, and competitive binding with unlabelled pepstatin A. BDP also bound to Na-APR-1M74 which was assessed by fluorescence polarization, but with an ∼50-fold reduction in the dissociation constant. Taken together, these assays comprise a “toolbox” that could be useful for the analyses of Na-APR-1M74 as it proceeds through the

  7. Molecular analysis of the distribution and phylogeny of dissimilatory adenosine-5'-phosphosulfate reductase-encoding genes (aprBA) among sulfur-oxidizing prokaryotes.

    PubMed

    Meyer, Birte; Kuever, Jan

    2007-10-01

    Dissimilatory adenosine-5'-phosphosulfate (APS) reductase (AprBA) is a key enzyme of the dissimilatory sulfate-reduction pathway. Homologues have been found in photo- and chemotrophic sulfur-oxidizing prokaryotes (SOP), in which they are postulated to operate in the reverse direction, oxidizing sulfite to APS. Newly developed PCR assays allowed the amplification of 92-93 % (2.1-2.3 kb) of the APS reductase locus aprBA. PCR-based screening of 116 taxonomically divergent SOP reference strains revealed a distribution of aprBA restricted to photo- and chemotrophs with strict anaerobic or at least facultative anaerobic lifestyles, including Chlorobiaceae, Chromatiaceae, Thiobacillus, Thiothrix and invertebrate symbionts. In the AprBA-based tree, the SOP diverge into two distantly related phylogenetic lineages, Apr lineages I and II, with the proteins of lineage II (Chlorobiaceae and others) in closer affiliation to the enzymes of the sulfate-reducing prokaryotes (SRP). This clustering is discordant with the dissimilatory sulfite reductase (DsrAB) phylogeny and indicates putative lateral aprBA gene transfer from SRP to the respective SOB lineages. In support of lateral gene transfer (LGT), several beta- and gammaproteobacterial species harbour both aprBA homologues, the DsrAB-congruent 'authentic' and the SRP-related, LGT-derived gene loci, while some relatives possess exclusively the SRP-related apr genes as a possible result of resident gene displacement by the xenologue. The two-gene state might be an intermediate in the replacement of the resident essential gene. Collected genome data demonstrate the correlation between the AprBA tree topology and the composition/arrangement of the apr gene loci (occurrence of qmoABC or aprM genes) from SRP and SOP of lineages I and II. The putative functional role of the SRP-related APS reductases in photo- and chemotrophic SOP is discussed.

  8. Response Time Analysis and Test of Protection System Instrument Channels for APR1400 and OPR1000

    SciTech Connect

    Lee, Chang Jae; Han, Seung; Yun, Jae Hee; Baek, Seung Min; Lee, Sang Jeong

    2015-07-01

    Safety limits are required to maintain the integrity of physical barriers designed to prevent the uncontrolled release of radioactive materials in nuclear power plants. The safety analysis establishes two critical constraints that include an analytical limit in terms of a measured or calculated variable, and a specific time after the analytical limit is reached to begin protective action. Keeping with the nuclear regulations and industry standards, satisfying these two requirements will ensure that the safety limit will not be exceeded during the design basis event, either an anticipated operational occurrence or a postulated accident. Various studies on the setpoint determination methodology for the safety-related instrumentation have been actively performed to ensure that the requirement of the analytical limit is satisfied. In particular, the protection setpoint methodology for the advanced power reactor 1400 (APP1400) and the optimized power reactor 1000 (OPR1000) has been recently developed to cover both the design basis event and the beyond design basis event. The developed setpoint methodology has also been quantitatively validated using specific computer programs and setpoint calculations. However, the safety of nuclear power plants cannot be fully guaranteed by satisfying the requirement of the analytical limit. In spite of the response time verification requirements of nuclear regulations and industry standards, it is hard to find the studies on the systematically integrated methodology regarding the response time evaluation. In cases of APR1400 and OPR1000, the response time analysis for the plant protection system is partially included in the setpoint calculation and the response time test is separately performed via the specific plant procedure. The test technique has a drawback which is the difficulty to demonstrate completeness of timing test. The analysis technique has also a demerit of resulting in extreme times that not actually possible. Thus

  9. The structure of two subgenomic RNAs from human influenza virus A/PR/8/34.

    PubMed Central

    Winter, G; Fields, S; Ratti, G

    1981-01-01

    The nucleotide sequences of two subgenomic RNA segments from influenza virus A/PR/8/34 have been determined by cloning viral cDNA into the vector M13mp7. Sequence analysis was facilitated by a re-cloning strategy which takes advantage of both wild-type and amber derivatives of the M13 vector. The RNA species (444 and 480 nucleotides) contain the 5' and 3' termini of segment 1 and therefore derive by simple internal deletions of this segment. However, these species are not exact copies of the terminal regions of the progenitor segment but contain a few base changes. These differences suggest that after these RNAs have arisen, their sequences can drift, presumably reflecting a lower selective pressure than on the standard RNA segments. PMID:7335495

  10. Use case driven approach to develop simulation model for PCS of APR1400 simulator

    SciTech Connect

    Dong Wook, Kim; Hong Soo, Kim; Hyeon Tae, Kang; Byung Hwan, Bae

    2006-07-01

    The full-scope simulator is being developed to evaluate specific design feature and to support the iterative design and validation in the Man-Machine Interface System (MMIS) design of Advanced Power Reactor (APR) 1400. The simulator consists of process model, control logic model, and MMI for the APR1400 as well as the Power Control System (PCS). In this paper, a use case driven approach is proposed to develop a simulation model for PCS. In this approach, a system is considered from the point of view of its users. User's view of the system is based on interactions with the system and the resultant responses. In use case driven approach, we initially consider the system as a black box and look at its interactions with the users. From these interactions, use cases of the system are identified. Then the system is modeled using these use cases as functions. Lower levels expand the functionalities of each of these use cases. Hence, starting from the topmost level view of the system, we proceeded down to the lowest level (the internal view of the system). The model of the system thus developed is use case driven. This paper will introduce the functionality of the PCS simulation model, including a requirement analysis based on use case and the validation result of development of PCS model. The PCS simulation model using use case will be first used during the full-scope simulator development for nuclear power plant and will be supplied to Shin-Kori 3 and 4 plant. The use case based simulation model development can be useful for the design and implementation of simulation models. (authors)

  11. Épidémiologie des brûlures de la main chez les enfants vus dans le Centre National des Brûlés et de Chirurgie Plastique de Casablanca, Maroc

    PubMed Central

    Rafik, A.; Lahlou, M.; Diouri, M.; Bahechar, N.; Chlihi, A.

    2015-01-01

    Summary Les brûlures de la main chez l’enfant constituent une source de séquelles invalidantes. A cet régard, la conservation et la restauration complète de la fonction de la main demeurent le but primordial de la prise en charge. Afin de répertorier les caractéristiques épidémiologiques, cliniques et évolutives des mains brûlées, nous avons réalisé une étude rétrospective étalée sur 4 ans, de janvier 2011 à janvier 2015. Cette étude a permis de colliger les cas de 313 enfants atteints de brûlure de la main vus dans le Centre National des Brulés et de Chirurgie Plastique du CHU Ibn Rochd de Casablanca. La majorité des brûlures touche les enfants de 3 à 6 ans (70% des cas), avec une légère prédominance masculine. La principale cause des brûlures survenant à cet âge est l’ébouillantement. Les brûlures par flamme représentent 33% des cas, celles par électricité 4,5%. Les brûlures chimiques et par contact sont anecdotiques (1 cas chacune). L’accident survient le plus souvent à domicile. Soixante douze pour cent des brûlures ont guéri spontanément. Afin de diminuer l’incidence de ces accidents, une approche préventive faite de sensibilisation et d’éducation devrait faire partie du cursus scolaire. PMID:27777543

  12. The French Advanced Course for Deployment Surgery (ACDS) called Cours Avancé de Chirurgie en Mission Extérieure (CACHIRMEX): history of its development and future prospects.

    PubMed

    Bonnet, Stéphane; Gonzalez, F; Mathieu, L; Boddaert, G; Hornez, E; Bertani, A; Avaro, J-P; Durand, X; Rongieras, F; Balandraud, P; Rigal, S; Pons, F

    2016-10-01

    The composition of a French Forward Surgical Team (FST) has remained constant since its creation in the early 1950s: 12 personnel, including a general and an orthopaedic surgeon. The training of military surgeons, however, has had to evolve to adapt to the growing complexities of modern warfare injuries in the context of increasing subspecialisation within surgery. The Advanced Course for Deployment Surgery (ACDS)-called Cours Avancé de Chirurgie en Mission Extérieure (CACHIRMEX)-has been designed to extend, reinforce and adapt the surgical skill set of the FST that will be deployed. Created in 2007 by the French Military Health Service Academy (Ecole du Val-de-Grâce), this annual course is composed of five modules. The surgical knowledge and skills necessary to manage complex military trauma and give medical support to populations during deployment are provided through a combination of didactic lectures, deployment experience reports and hands-on workshops. The course is now a compulsory component of initial surgical training for junior military surgeons and part of the Continuous Medical Education programme for senior military surgeons. From 2012, the standardised content of the ACDS paved the way for the development of two more team-training courses: the FST and the Special Operation Surgical Team training. The content of this French military original war surgery course is described, emphasising its practical implications and future prospects. The military surgical training needs to be regularly assessed to deliver the best quality of care in an context of evolving modern warfare casualties. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  13. The Relationship between AP[R] Exam Performance and College Outcomes. Research Report No. 2009-4

    ERIC Educational Resources Information Center

    Mattern, Krista D.; Shaw, Emily J.; Xiong, Xinhui

    2009-01-01

    This study focused on the relationship between students' Advanced Placement Program[R] (AP[R]) performance in AP English Language, Biology, Calculus, and U.S. History, and their subsequent college success. For each AP Exam studied, students were divided into three groups according to their AP Exam performance (no AP Exam taken, score of 1 or 2,…

  14. Prenatal transportation alters the acute phase response (APR) of bull calves exposed to a lipopolysaccharide (LPS) challenge

    USDA-ARS?s Scientific Manuscript database

    This study was designed to determine if prenatal transportation influences the acute phase response (APR) to a postnatal Lipopolysaccharide (LPS) challenge. Pregnant Brahman cows (n=96) matched by age and parity were separated into transported (TRANS; n=48; transported for 2 hours on gestational day...

  15. Mimicking acute and chronic stress exposure in naive beef steers alters the acute phase response (APR) associated with vaccination

    USDA-ARS?s Scientific Manuscript database

    This study was designed to determine the effect of an acute versus chronic stress model on the APR associated with vaccination in naïve beef steers. Steers (n=32; 209 +/- 8 kg) were blocked by body weight and assigned to 1 of 3 treatments: 1) Chronic stress (CHR), 0.5 mg/kg body weight dexamethasone...

  16. 48 CFR 1552.235-75 - Access to Toxic Substances Control Act Confidential Business Information (APR 1996).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Access to Toxic Substances Control Act Confidential Business Information (APR 1996). 1552.235-75 Section 1552.235-75 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY CLAUSES AND FORMS SOLICITATION PROVISIONS AND...

  17. 48 CFR 1552.235-75 - Access to Toxic Substances Control Act Confidential Business Information (APR 1996).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Access to Toxic Substances Control Act Confidential Business Information (APR 1996). 1552.235-75 Section 1552.235-75 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY CLAUSES AND FORMS SOLICITATION PROVISIONS AND...

  18. The Relationship between AP[R] Exam Performance and College Outcomes. Research Report No. 2009-4

    ERIC Educational Resources Information Center

    Mattern, Krista D.; Shaw, Emily J.; Xiong, Xinhui

    2009-01-01

    This study focused on the relationship between students' Advanced Placement Program[R] (AP[R]) performance in AP English Language, Biology, Calculus, and U.S. History, and their subsequent college success. For each AP Exam studied, students were divided into three groups according to their AP Exam performance (no AP Exam taken, score of 1 or 2,…

  19. Validating the AP[R] German Language Exam through a Curricular Survey of Third-Year College Language Courses

    ERIC Educational Resources Information Center

    Bischof, Deborah Lokai

    2005-01-01

    Curriculum surveys are used periodically to validate the use of Advanced Place Program[R] (AP[R]) Exams as assessments of skills required for advanced college-level study. In the case of AP German Language, the target level is third-year college language study. This article presents results from a 2003 curriculum survey completed by third-year…

  20. The Experience of Staging Nijinsky's "L'Apres-Midi d'un Faune" in a Higher Education Dance Program

    ERIC Educational Resources Information Center

    Curran, Tina

    2010-01-01

    This study documented the experiences of staging Vaslav Nijinsky's "L'Apres-midi d'un Faune" in a higher education dance program. The ballet was staged from Labanotation. Research questions focused on teaching and learning pedagogy, characterization of the process over time, experiences of the participants and teaching approaches. The project…

  1. 15 CFR 783.3 - Reports containing information determined by BIS not to be required by the APR.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 2 2014-01-01 2014-01-01 false Reports containing information... Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE... § 783.3 Reports containing information determined by BIS not to be required by the APR. If you submit a...

  2. The Experience of Staging Nijinsky's "L'Apres-Midi d'un Faune" in a Higher Education Dance Program

    ERIC Educational Resources Information Center

    Curran, Tina

    2010-01-01

    This study documented the experiences of staging Vaslav Nijinsky's "L'Apres-midi d'un Faune" in a higher education dance program. The ballet was staged from Labanotation. Research questions focused on teaching and learning pedagogy, characterization of the process over time, experiences of the participants and teaching approaches. The project…

  3. Isolation of ara-lac gene fusions in Salmonella typhimurium LT2 by using transducing bacteriophage Mu d (Apr lac).

    PubMed

    Lee, J H; Heffernan, L; Wilcox, G

    1980-09-01

    A specialized Mu transducing phage containing a gene encoding ampicillin resistance and the lac structural genes without the lac promotor [Mu d(apr lac)] has been constructed and used to create gene fusions in Escherichia coli (M. J. Cadadaban and S. N. Cohen, Proc. Natl. Acad. Sci. U.S.A. 76:4530--4533, 1979). Transposition of the Mu d(Apr lac) phage to chromosomal sites can result in lac expression being controlled by a chromosomal promoter. We have constructed an Escherichia coli K-12 strain in which the Mu d(Apr lac) phage is integrated into an F factor. The F+::Mu d(Apr lac) was then transferred by conjugation into a Salmonella typhimurium strain that was sensitive to L-arabinose. Strains containing gene fusions were selected as L-arabinose-resistant colonies after partial induction of the phage. Two classes of ara-lac fusion strains were isolated: (i) araC-lac fusions in which the expression of beta-galactosidase synthesis was constitutuve and not inducible by L-arabinose; and ((ii) fusion of the lac genes to the ara structural genes in which the expression of beta-galatosidase synthesis was induced 263-fold by L-arabinose.

  4. Homology modeling of dissimilatory APS reductases (AprBA) of sulfur-oxidizing and sulfate-reducing prokaryotes.

    PubMed

    Meyer, Birte; Kuever, Jan

    2008-01-30

    The dissimilatory adenosine-5'-phosphosulfate (APS) reductase (cofactors flavin adenine dinucleotide, FAD, and two [4Fe-4S] centers) catalyzes the transformation of APS to sulfite and AMP in sulfate-reducing prokaryotes (SRP); in sulfur-oxidizing bacteria (SOB) it has been suggested to operate in the reverse direction. Recently, the three-dimensional structure of the Archaeoglobus fulgidus enzyme has been determined in different catalytically relevant states providing insights into its reaction cycle. Full-length AprBA sequences from 20 phylogenetically distinct SRP and SOB species were used for homology modeling. In general, the average accuracy of the calculated models was sufficiently good to allow a structural and functional comparison between the beta- and alpha-subunit structures (78.8-99.3% and 89.5-96.8% of the AprB and AprA main chain atoms, respectively, had root mean square deviations below 1 A with respect to the template structures). Besides their overall conformity, the SRP- and SOB-derived models revealed the existence of individual adaptations at the electron-transferring AprB protein surface presumably resulting from docking to different electron donor/acceptor proteins. These structural alterations correlated with the protein phylogeny (three major phylogenetic lineages: (1) SRP including LGT-affected Archaeoglobi and SOB of Apr lineage II, (2) crenarchaeal SRP Caldivirga and Pyrobaculum, and (3) SOB of the distinct Apr lineage I) and the presence of potential APS reductase-interacting redox complexes. The almost identical protein matrices surrounding both [4Fe-4S] clusters, the FAD cofactor, the active site channel and center within the AprB/A models of SRP and SOB point to a highly similar catalytic process of APS reduction/sulfite oxidation independent of the metabolism type the APS reductase is involved in and the species it has been originated from. Based on the comparative models, there are no significant structural differences between

  5. Homology Modeling of Dissimilatory APS Reductases (AprBA) of Sulfur-Oxidizing and Sulfate-Reducing Prokaryotes

    PubMed Central

    Meyer, Birte; Kuever, Jan

    2008-01-01

    Background The dissimilatory adenosine-5′-phosphosulfate (APS) reductase (cofactors flavin adenine dinucleotide, FAD, and two [4Fe-4S] centers) catalyzes the transformation of APS to sulfite and AMP in sulfate-reducing prokaryotes (SRP); in sulfur-oxidizing bacteria (SOB) it has been suggested to operate in the reverse direction. Recently, the three-dimensional structure of the Archaeoglobus fulgidus enzyme has been determined in different catalytically relevant states providing insights into its reaction cycle. Methodology/Principal Findings Full-length AprBA sequences from 20 phylogenetically distinct SRP and SOB species were used for homology modeling. In general, the average accuracy of the calculated models was sufficiently good to allow a structural and functional comparison between the beta- and alpha-subunit structures (78.8–99.3% and 89.5–96.8% of the AprB and AprA main chain atoms, respectively, had root mean square deviations below 1 Å with respect to the template structures). Besides their overall conformity, the SRP- and SOB-derived models revealed the existence of individual adaptations at the electron-transferring AprB protein surface presumably resulting from docking to different electron donor/acceptor proteins. These structural alterations correlated with the protein phylogeny (three major phylogenetic lineages: (1) SRP including LGT-affected Archaeoglobi and SOB of Apr lineage II, (2) crenarchaeal SRP Caldivirga and Pyrobaculum, and (3) SOB of the distinct Apr lineage I) and the presence of potential APS reductase-interacting redox complexes. The almost identical protein matrices surrounding both [4Fe-4S] clusters, the FAD cofactor, the active site channel and center within the AprB/A models of SRP and SOB point to a highly similar catalytic process of APS reduction/sulfite oxidation independent of the metabolism type the APS reductase is involved in and the species it has been originated from. Conclusions Based on the comparative models

  6. General Relativistic Magnetohydrodynamic Simulations of Binary Neutron Star Mergers with the APR4 Equation of State

    NASA Astrophysics Data System (ADS)

    Endrizzi, Andrea; Ciolfi, Riccardo; Giacomazzo, Bruno; Kastaun, Wolfgang; Kawamura, Takumu

    2016-03-01

    We present new results of fully general relativistic magnetohydrodynamic (GRMHD) simulations of binary neutron star (BNS) mergers performed with the Whisky code. All the models use a piecewise polytropic approximation of the APR4 equation of state (EOS) for cold matter, together with a ''hybrid'' part to incorporate thermal effects during the evolution. We consider both equal and unequal-mass models, with total masses such that either a supramassive NS or a black hole (BH) is formed after merger. Each model is evolved with and without a magnetic field initially confined to the stellar interior. We present the different gravitational wave (GW) signals as well as a detailed description of the matter dynamics (magnetic field evolution, ejected mass, post-merger remnant properties, disk mass). Our new simulations provide a further important step in the understanding of these GW sources and their possible connection with the engine of short gamma-ray bursts (both in the ``standard'' and in the ``time-reversal'' scenarios) and with other electromagnetic counterparts.

  7. General relativistic magnetohydrodynamic simulations of binary neutron star mergers with the APR4 equation of state

    NASA Astrophysics Data System (ADS)

    Endrizzi, A.; Ciolfi, R.; Giacomazzo, B.; Kastaun, W.; Kawamura, T.

    2016-08-01

    We present new results of fully general relativistic magnetohydrodynamic simulations of binary neutron star (BNS) mergers performed with the Whisky code. All the models use a piecewise polytropic approximation of the APR4 equation of state for cold matter, together with a ‘hybrid’ part to incorporate thermal effects during the evolution. We consider both equal and unequal-mass models, with total masses such that either a supramassive NS or a black hole is formed after merger. Each model is evolved with and without a magnetic field initially confined to the stellar interior. We present the different gravitational wave (GW) signals as well as a detailed description of the matter dynamics (magnetic field evolution, ejected mass, post-merger remnant/disk properties). Our simulations provide new insights into BNS mergers, the associated GW emission and the possible connection with the engine of short gamma-ray bursts (both in the ‘standard’ and in the ‘time-reversal’ scenarios) and other electromagnetic counterparts.

  8. Modeling of melt retention in EU-APR1400 ex-vessel core catcher

    SciTech Connect

    Granovsky, V. S.; Sulatsky, A. A.; Khabensky, V. B.; Sulatskaya, M. B.; Gusarov, V. V.; Almyashev, V. I.; Komlev, A. A.; Bechta, S.; Kim, Y. S.; Park, R. J.; Kim, H. Y.; Song, J. H.

    2012-07-01

    A core catcher is adopted in the EU-APR1400 reactor design for management and mitigation of severe accidents with reactor core melting. The core catcher concept incorporates a number of engineering solutions used in the catcher designs of European EPR and Russian WER-1000 reactors, such as thin-layer corium spreading for better cooling, retention of the melt in a water-cooled steel vessel, and use of sacrificial material (SM) to control the melt properties. SM is one of the key elements of the catcher design and its performance is critical for melt retention efficiency. This SM consists of oxide components, but the core catcher also includes sacrificial steel which reacts with the metal melt of the molten corium to reduce its temperature. The paper describes the required properties of SM. The melt retention capability of the core catcher can be confirmed by modeling the heat fluxes to the catcher vessel to show that it will not fail. The fulfillment of this requirement is demonstrated on the example of LBLOCA severe accident. Thermal and physicochemical interactions between the oxide and metal melts, interactions of the melts with SM, sacrificial steel and vessel, core catcher external cooling by water and release of non-condensable gases are modeled. (authors)

  9. Acute exercise does not induce an acute phase response (APR) in Standardbred trotters.

    PubMed

    Kristensen, Lena; Buhl, Rikke; Nostell, Katarina; Bak, Lars; Petersen, Ellen; Lindholm, Maria; Jacobsen, Stine

    2014-04-01

    The purpose of the study was to investigate whether acute strenuous exercise (1600- to 2500-m race) would elicit an acute phase response (APR) in Standardbred trotters. Blood levels of several inflammatory markers [serum amyloid A (SAA), haptoglobin, fibrinogen, white blood cell count (WBC), and iron], muscle enzymes [creatinine kinase (CK) and aspartate transaminase (AST)], and hemoglobin were assessed in 58 Standardbred trotters before and after racing. Hemoglobin levels increased and iron levels decreased 12 to 14 h after racing and haptoglobin concentrations, white blood cell counts, and iron levels were decreased 2 and/or 7 d after racing. Concentrations of CK, AST, SAA, and fibrinogen were unaltered in response to racing. Acute strenuous exercise did not elicit an acute phase reaction. The observed acute increase in hemoglobin levels and decreases in haptoglobin and iron levels may have been caused by exercise-induced hemolysis, which indicates that horses might experience a condition similar to athlete's anemia in humans. The pathogenesis and clinical implications of the hematological and blood-biochemical changes elicited by acute exercise in Standardbred trotters in the present study warrant further investigation.

  10. Purification and characterization of a small size protease from Bacillus sp. APR-4.

    PubMed

    Kumar, D; Bhalla, T C

    2004-05-01

    A thermostable extracellular protease of Bacillus sp. APR-4 was purified by size-exclusion and ion-exchange chromatographic methods and its properties were studied. The purified enzyme had a specific activity of 21,000 U/mg of protein and gave single band on SDS/PAGE with a molecular mass of 16.9 KDa. This protease had an optimal pH of 9 and exhibited its highest activity at 60 degrees C. The enzyme activity was inhibited by EDTA, suggesting the presence of metal residue at the active site. Ca2+ (5 mM) had stabilising effect on the activity of protease, but Cu2+ (5 mM) had inhibitory effect. The enzyme exhibited highest specificity towards casein (1%) and had a Km of 26.3 mg/ml and a Vmax of 47.6 U/mg with casein as a substrate. The stability of this enzyme was evaluated in the presence of some organic solvents and the enzyme was stable in methanol, petroleum ether and ethanol. Detergents (Wheel, Farishta) had stimulatory effect on the activity of this enzyme.

  11. Résultats fonctionnels de la chirurgie de la cataracte par phacoalternative avec implantation en chambre postérieure: à propos de 300 cas à Bobo Dioulasso (Burkina Faso)

    PubMed Central

    Diallo, Jean Wenceslas; Meda, Nonfounikoun; Ahnoux-Zabsonre, Ahgbatouhabéba; Yameogo, Claudette; Dolo, Mariam; Sanou, Jérôme; Daboue, Arsène

    2015-01-01

    La cataracte est la première cause de cécité curable dans le monde. Son traitement est chirurgical. Le but de notre travail a été d’évaluer les résultats de la phacoalternative ou la chirurgie de la cataracte à petite incision. Il s'est agi d'une étude transversale descriptive à collecte prospective allant du 1er janvier au 31 septembre 2014, chez des patients âgés d'au moins 40 ans. Les données socio-démographiques, l'acuité visuelle, l'astigmatisme et les complications ont été évalués. Nous avons inclus 300 yeux de 286 patients. L’âge moyen était de 66 ans (écart type 9,93) avec une prédominance masculine de 57,7%. Les co-morbidités étaient dominées par l'hypertension artérielle 30,33% des cas. L'acuité visuelle pré-opératoire était de moins de 1/20è dans 70, 7% des cas. En biométrie, la puissance moyenne était de 21,50 dioptries. L'implant posé a été adéquat dans 60%. Les principales complications per-opératoires étaient le chémosis post-anesthésie 4,67% et l'issue de vitrée moins de 2% des cas. Les complications post opératoires précoces ont été dominées par l’œdème de cornée 26,33%, et les complications tardives par la cataracte secondaire. L'astigmatisme induit était de 1, 12 dioptrie en moyenne (écart type 1,26). Sans correction, les résultats visuels étaient mauvais dans moins de 1%, limites dans 31%, et bons 68% suivants les normes de l'Organisation Mondiale de la Santé. La phacoalternative donne des résultats satisfaisants, avec peu de complications. L'amélioration du plateau technique et la disponibilité d'implants adéquats pourraient les améliorer. PMID:26140073

  12. Anti-Influenza Activity of Betulinic Acid from Zizyphus jujuba on Influenza A/PR/8 Virus

    PubMed Central

    Hong, Eun-Hye; Song, Jae Hyoung; Kang, Kyo Bin; Sung, Sang Hyun; Ko, Hyun-Jeong; Yang, Heejung

    2015-01-01

    Betulinic acid, a pentacyclic triterpene isolated from Jujube tree (Zizyphus jujuba Mill), has been known for a wide range of biological and medicinal properties such as antibacterial, antimalarial, anti-inflammatory, antihelmintic, antinociceptive, and anticancer activities. In the study, we investigated the antiviral activity on influenza A/PR/8 virus infected A549 human lung adenocarcinoma epithelial cell line and C57BL/6 mice. Betulinic acid showed the anti-influenza viral activity at a concentration of 50 μM without a significant cytotoxicity in influenza A/PR/8 virus infected A549 cells. Also, betulinic acid significantly attenuated pulmonary pathology including increased necrosis, numbers of inflammatory cells and pulmonary edema induced by influenza A/PR/8 virus infection compared with vehicle- or oseltamivir-treated mice in vivo model. The down-regulation of IFN-γ level, which is critical for innate and adaptive immunity in viral infection, after treating of betulinic acid in mouse lung. Based on the obtained results, it is suggested that betulinic acid can be the potential therapeutic agent for virus infection via anti-inflammatory activity. PMID:26157551

  13. Diversity of sulfur-cycle prokaryotes in freshwater lake sediments investigated using aprA as the functional marker gene.

    PubMed

    Watanabe, Tomohiro; Kojima, Hisaya; Takano, Yoshinori; Fukui, Manabu

    2013-09-01

    The diversity of sulfate-reducing prokaryotes (SRPs) and sulfur-oxidizing prokaryotes (SOPs) in freshwater lake ecosystems was investigated by cloning and sequencing of the aprA gene, which encodes for a key enzyme in dissimilatory sulfate reduction and sulfur oxidation. To understand their diversity better, the spatial distribution of aprA genes was investigated in sediments collected from six geographically distant lakes in Antarctica and Japan, including a hypersaline lake for comparison. The microbial community compositions of freshwater sediments and a hypersaline sediment showed notable differences. The clones affiliated with Desulfobacteraceae and Desulfobulbaceae were frequently detected in all freshwater lake sediments. The SOP community was mainly composed of four major phylogenetic groups. One of them formed a monophyletic cluster with a sulfur-oxidizing betaproteobacterium, Sulfuricella denitrificans, but the others were not assigned to specific genera. In addition, the AprA sequences, which were not clearly affiliated to either SRP or SOP lineages, dominated the libraries from four freshwater lake sediments. The results showed the wide distribution of some sulfur-cycle prokaryotes across geographical distances and supported the idea that metabolic flexibility is an important feature for SRP survival in low-sulfate environments. Copyright © 2013 Elsevier GmbH. All rights reserved.

  14. Facteurs déterminants le regret après ligature tubaire

    PubMed Central

    Boufettal, Houssine; Mahdaoui, Sakher; Samouh, Naïma

    2014-01-01

    Introduction La ligature tubaire peut générer regret. Le but de cette étude est d’étudier le vécu après la stérilisation ainsi que le regret et ses facteurs de risque. Méthodes Il s'agit d'une étude rétrospective chez 52 femmes stérilisées entre 2004 et 2010. Résultats Vingt cinq (48%) femmes avaient regretté la réalisation de la ligature tubaire. La moyenne d’âge était de 40,5 ans. Le temps consacré aux explications était très court dans tous les cas. Trois quart des femmes n’était pas au courant des complications de la ligature tubaire. Le regret était dû au facteur religieux (23%), aux algies pelviennes (11,5%), au désir d'autres enfants (9,6%) ou à la prise de connaissance d'autres moyens contraceptifs (3,9%). Conclusion Un certains nombre de facteurs de risque de regret de la ligature tubaire sont retrouvés dans la littérature, comme dans notre série, dont l’âge, le désir de procréer, l'information incomplète, le délai de réflexion et le facteur religieux. PMID:25309644

  15. Tabula viva chirurgi: a living surgical document

    PubMed Central

    Swart, Marius J; Joubert, Gina; van den Berg, Jan-Albert; van Zyl, Gert J

    2016-01-01

    Summary Aim: The purpose of this article is to present the results of a private cardiac surgical practice. This information could also serve as a hermeneutical text for new wisdom. Methods: A personal database of 1 750 consecutive patients who had had coronary artery bypass graft (CABG) surgery was statistically analysed. Mortality and major morbidity figures were compared with large registries. Risk factors for postoperative death were determined. Results: Over a period of 12 years, 1 344 (76.8%) males and 406 (23.2%) females were operated on. The observed mortality rate was 3.03% and the expected mortality rate (EuroSCORE) was 3.87%. After stepwise logistic regression, independent risk factors for death were urgency (intra-aortic balloon pump), renal impairment (chronic kidney disease, stage III), re-operation and an additional procedure. Apart from the 53 deaths, another 91 patients had major complications. Conclusion: Mortality and morbidity rates compared favourably with other international registries. Mortality was related to co-morbidities. This outcome contributes to a hermeneutical understanding focusing on new spiritual wisdom and meaning for the surgeon. PMID:27841902

  16. Predictors of exclusive breastfeeding: observations from the Alberta pregnancy outcomes and nutrition (APrON) study

    PubMed Central

    2013-01-01

    Background Despite growing evidence that supports the importance of 6-month exclusive breastfeeding, few Canadian mothers adhere to this, and early weaning onto solids is a common practice. This study assessed infant feeding transitions during the first 6 months postpartum and factors that predicted exclusive breastfeeding to 3 and 6 months. Methods This prospective cohort study was part of the Alberta Pregnancy Outcomes and Nutrition study (APrON). From an initial sample of 600 pregnant women recruited from Edmonton and Calgary, 402 mothers provided complete details at 3 months postpartum; 300 stayed on to provide information at 6 months postpartum. During pregnancy and at 3 and 6 months postpartum, data on maternal and infant socio-demographic, behavior, and feeding were collected. Results Even though there was a high rate of “ever having breastfed” (98.6%), exclusive breastfeeding rates for 3 and 6 months were 54.0% and 15.3%, respectively. After controlling for potential confounders, the study showed that mothers who held post-graduate university degrees were 3.76 times more likely to breastfeed exclusively for 6 months than those without a university degree (95% CI: 1.30-10.92; p = 0.015). In addition, mother of previous children were more likely to breastfeed exclusively for 6 months (OR: 2.21, 95% CI: 1.08-4.52; p = 0.031). Mothers who were in the highest quartile of the Iowa Infant Feeding Attitude Score were 4.29 and 5.40 times more likely to breastfeed exclusively for 3 months (95% CI: 1.31-14.08; p-trend < 0.001) and 6 months (95% CI: 2.75-10.60; P-trend < 0.001), respectively. Conclusions The 6-month exclusive breastfeeding rate in Alberta is considerably below national and international breastfeeding recommendations. Professional advice that focuses on prenatal maternal knowledge, attitudes, and misperceptions may promote adherence to World Health Organization breastfeeding guidelines. Knowing that exclusive breastfeeding

  17. Suivi après le traitement du cancer du sein

    PubMed Central

    Sisler, Jeffrey; Chaput, Geneviève; Sussman, Jonathan; Ozokwelu, Emmanuel

    2016-01-01

    Résumé Objectif Offrir aux médecins de famille un résumé des recommandations fondées sur les données probantes pour guider les soins aux survivantes traitées pour le cancer du sein. Qualité des données Une recherche documentaire a été effectuée dans MEDLINE entre 2000 et 2016 à l’aide des mots-clés anglais suivants : breast cancer, survivorship, follow-up care, aftercare, guidelines et survivorship care plans, en se concentrant sur la revue des lignes directrices publiées récemment par les organismes nationaux de cancérologie. Les données étaient de niveaux I à III. Message principal Les soins aux survivantes comportent 4 facettes : surveillance et dépistage, prise en charge des effets à long terme, promotion de la santé et coordination des soins. La surveillance des récidives ne se traduit que par une mammographie annuelle, et le dépistage d’autres cancers doit suivre les lignes directrices basées sur la population. La prise en charge des effets à long terme du cancer et de son traitement aborde des problèmes courants tels la douleur, la fatigue, le lymphœdème, la détresse et les effets indésirables des médicaments, de même que les préoccupations à long terme comme la santé du cœur et des os. La promotion de la santé met en relief les bienfaits de l’activité chez les survivantes du cancer, avec l’accent mis sur l’activité physique. Les soins aux survivantes sont de meilleure qualité lorsque divers services et professionnels de la santé participent aux soins, et le médecin de famille joue un rôle important dans la coordination des soins. Conclusion Les médecins de famille sont de plus en plus souvent les principaux fournisseurs de soins de suivi après le traitement du cancer du sein. Le cancer du sein doit être considéré comme une affection médicale chronique, même chez les femmes en rémission, et les patientes profitent de la même approche que celle utilisée pour les autres affections chroniques en

  18. Processing of High Resolution, Multiparametric Radar Data for the Airborne Dual-Frequency Precipitation Radar APR-2

    NASA Technical Reports Server (NTRS)

    Tanelli, Simone; Meagher, Jonathan P.; Durden, Stephen L.; Im, Eastwood

    2004-01-01

    Following the successful Precipitation Radar (PR) of the Tropical Rainfall Measuring Mission, a new airborne, 14/35 GHz rain profiling radar, known as Airborne Precipitation Radar - 2 (APR-2), has been developed as a prototype for an advanced, dual-frequency spaceborne radar for a future spaceborne precipitation measurement mission. . This airborne instrument is capable of making simultaneous measurements of rainfall parameters, including co-pol and cross-pol rain reflectivities and vertical Doppler velocities, at 14 and 35 GHz. furthermore, it also features several advanced technologies for performance improvement, including real-time data processing, low-sidelobe dual-frequency pulse compression, and dual-frequency scanning antenna. Since August 2001, APR-2 has been deployed on the NASA P3 and DC8 aircrafts in four experiments including CAMEX-4 and the Wakasa Bay Experiment. Raw radar data are first processed to obtain reflectivity, LDR (linear depolarization ratio), and Doppler velocity measurements. The dataset is then processed iteratively to accurately estimate the true aircraft navigation parameters and to classify the surface return. These intermediate products are then used to refine reflectivity and LDR calibrations (by analyzing clear air ocean surface returns), and to correct Doppler measurements for the aircraft motion. Finally, the the melting layer of precipitation is detected and its boundaries and characteristics are identifIed at the APR-2 range resolution of 30m. The resulting 3D dataset will be used for validation of other airborne and spaceborne instruments, development of multiparametric rain/snow retrieval algorithms and melting layer characterization and statistics.

  19. Processing of High Resolution, Multiparametric Radar Data for the Airborne Dual-Frequency Precipitation Radar APR-2

    NASA Technical Reports Server (NTRS)

    Tanelli, Simone; Meagher, Jonathan P.; Durden, Stephen L.; Im, Eastwood

    2004-01-01

    Following the successful Precipitation Radar (PR) of the Tropical Rainfall Measuring Mission, a new airborne, 14/35 GHz rain profiling radar, known as Airborne Precipitation Radar - 2 (APR-2), has been developed as a prototype for an advanced, dual-frequency spaceborne radar for a future spaceborne precipitation measurement mission. . This airborne instrument is capable of making simultaneous measurements of rainfall parameters, including co-pol and cross-pol rain reflectivities and vertical Doppler velocities, at 14 and 35 GHz. furthermore, it also features several advanced technologies for performance improvement, including real-time data processing, low-sidelobe dual-frequency pulse compression, and dual-frequency scanning antenna. Since August 2001, APR-2 has been deployed on the NASA P3 and DC8 aircrafts in four experiments including CAMEX-4 and the Wakasa Bay Experiment. Raw radar data are first processed to obtain reflectivity, LDR (linear depolarization ratio), and Doppler velocity measurements. The dataset is then processed iteratively to accurately estimate the true aircraft navigation parameters and to classify the surface return. These intermediate products are then used to refine reflectivity and LDR calibrations (by analyzing clear air ocean surface returns), and to correct Doppler measurements for the aircraft motion. Finally, the the melting layer of precipitation is detected and its boundaries and characteristics are identifIed at the APR-2 range resolution of 30m. The resulting 3D dataset will be used for validation of other airborne and spaceborne instruments, development of multiparametric rain/snow retrieval algorithms and melting layer characterization and statistics.

  20. Multi-analytical characterisation of D'Aprés Cormon by José Veloso Salgado

    NASA Astrophysics Data System (ADS)

    Cardeira, A. M.; Longelin, S.; Costa, S.; Candeias, A.; Carvalho, M. L.; Manso, M.

    2014-07-01

    This case study reveals the analytical characterisation carried out on 'D'Aprés Cormon' (1891) by Veloso Salgado, a copy of 'Caïn' (1880) by Fernando Cormon, belonging nowadays to Musée d'Orsay. Infrared Reflectography made in situ revealed underdrawing grid that was used to transpose the original painting to a smaller scale, pictorial style, execution method and retouched/restored areas. In situ EDXRF analysis together with Raman microscopy allowed the identification of gypsum, lead white, titanium white, yellow ochre, vermilion, ultramarine and lamp black. These results provide valuable information about the Salgado's palette and his production technique.

  1. Expression, purification, and characterization of the Necator americanus aspartic protease-1 (Na-APR-1 (M74)) antigen, a component of the bivalent human hookworm vaccine

    PubMed Central

    Seid, Christopher A; Curti, Elena; Jones, R Mark; Hudspeth, Elissa; Rezende, Wanderson; Pollet, Jeroen; Center, Lori; Versteeg, Leroy; Pritchard, Sonya; Musiychuk, Konstantin; Yusibov, Vidadi; Hotez, Peter J; Bottazzi, Maria Elena

    2015-01-01

    Over 400 million people living in the world's poorest developing nations are infected with hookworms, mostly of the genus Necator americanus. A bivalent human hookworm vaccine composed of the Necator americanus Glutathione S-Transferase-1 (Na-GST-1) and the Necator americanus Aspartic Protease-1 (Na-APR-1 (M74)) is currently under development by the Sabin Vaccine Institute Product Development Partnership (Sabin PDP). Both monovalent vaccines are currently in Phase 1 trials. Both Na-GST-1 and Na-APR-1 antigens are expressed as recombinant proteins. While Na-GST-1 was found to express with high yields in Pichia pastoris, the level of expression of Na-APR-1 in this host was too low to be suitable for a manufacturing process. When the tobacco plant Nicotiana benthamiana was evaluated as an expression system, acceptable levels of solubility, yield, and stability were attained. Observed expression levels of Na-APR-1 (M74) using this system are ∼300 mg/kg. Here we describe the achievements and obstacles encountered during process development as well as characterization and stability of the purified Na-APR-1 (M74) protein and formulated vaccine. The expression, purification and analysis of purified Na-APR-1 (M74) protein obtained from representative 5 kg reproducibility runs performed to qualify the Na-APR-1 (M74) production process is also presented. This process has been successfully transferred to a pilot plant and a 50 kg scale manufacturing campaign under current Good Manufacturing Practice (cGMP) has been performed. The 50 kg run has provided a sufficient amount of protein to support the ongoing hookworm vaccine development program of the Sabin PDP. PMID:25905574

  2. Expression, purification, and characterization of the Necator americanus aspartic protease-1 (Na-APR-1 (M74)) antigen, a component of the bivalent human hookworm vaccine.

    PubMed

    Seid, Christopher A; Curti, Elena; Jones, R Mark; Hudspeth, Elissa; Rezende, Wanderson; Pollet, Jeroen; Center, Lori; Versteeg, Leroy; Pritchard, Sonya; Musiychuk, Konstantin; Yusibov, Vidadi; Hotez, Peter J; Bottazzi, Maria Elena

    2015-01-01

    Over 400 million people living in the world's poorest developing nations are infected with hookworms, mostly of the genus Necator americanus. A bivalent human hookworm vaccine composed of the Necator americanus Glutathione S-Transferase-1 (Na-GST-1) and the Necator americanus Aspartic Protease-1 (Na-APR-1 (M74)) is currently under development by the Sabin Vaccine Institute Product Development Partnership (Sabin PDP). Both monovalent vaccines are currently in Phase 1 trials. Both Na-GST-1 and Na-APR-1 antigens are expressed as recombinant proteins. While Na-GST-1 was found to express with high yields in Pichia pastoris, the level of expression of Na-APR-1 in this host was too low to be suitable for a manufacturing process. When the tobacco plant Nicotiana benthamiana was evaluated as an expression system, acceptable levels of solubility, yield, and stability were attained. Observed expression levels of Na-APR-1 (M74) using this system are ∼300 mg/kg. Here we describe the achievements and obstacles encountered during process development as well as characterization and stability of the purified Na-APR-1 (M74) protein and formulated vaccine. The expression, purification and analysis of purified Na-APR-1 (M74) protein obtained from representative 5 kg reproducibility runs performed to qualify the Na-APR-1 (M74) production process is also presented. This process has been successfully transferred to a pilot plant and a 50 kg scale manufacturing campaign under current Good Manufacturing Practice (cGMP) has been performed. The 50 kg run has provided a sufficient amount of protein to support the ongoing hookworm vaccine development program of the Sabin PDP.

  3. The AprV5 Subtilase Is Required for the Optimal Processing of All Three Extracellular Serine Proteases from Dichelobacter nodosus

    PubMed Central

    Han, Xiaoyan; Kennan, Ruth M.; Steer, David L.; Smith, A. Ian; Whisstock, James C.; Rood, Julian I.

    2012-01-01

    Dichelobacter nodosus is the principal causative agent of ovine footrot and its extracellular proteases are major virulence factors. Virulent isolates of D. nodosus secrete three subtilisin-like serine proteases: AprV2, AprV5 and BprV. These enzymes are each synthesized as precursor molecules that include a signal (pre-) peptide, a pro-peptide and a C-terminal extension, which are processed to produce the mature active forms. The function of the C-terminal regions of these proteases and the mechanism of protease processing and secretion are unknown. AprV5 contributes to most of the protease activity secreted by D. nodosus. To understand the role of the C-terminal extension of AprV5, we constructed a series of C-terminal-deletion mutants in D. nodosus by allelic exchange. The proteases present in the resultant mutants and their complemented derivatives were examined by protease zymogram analysis, western blotting and mass spectrometry. The results showed that the C-terminal region of AprV5 is required for the normal expression of protease activity, deletion of this region led to a delay in the processing of these enzymes. D. nodosus is an unusual bacterium in that it produces three closely related extracellular serine proteases. We have now shown that one of these enzymes, AprV5, is responsible for its own maturation, and for the optimal cleavage of AprV2 and BprV, to their mature active forms. These studies have increased our understanding of how this important pathogen processes these virulence-associated extracellular proteases and secretes them into its external environment. PMID:23112874

  4. Characterisation of the Thermostable Protease AprX in Strains of Pseudomonas Fluorescens and Impact on the Shelf-life of Dairy Products: Preliminary Results

    PubMed Central

    Andreani, Nadia Andrea; Carraro, Lisa; Fasolato, Luca; Balzan, Stefania; Lucchini, Rosaria; Novelli, Enrico; Cardazzo, Barbara

    2016-01-01

    Bacterial proteases are involved in food spoilage and shelf-life reduction. Among the bacterial proteases, a predominant role in spoilage of dairy products seems to be played by the thermostable metallo-protease AprX, which is produced by various strains of Pseudomonas fluorescens. Differences in AprX enzyme activity among different strains were highlighted, but the most proteolytic strains were not identified. In this study, the presence of the aprX gene was evaluated in 69 strains isolated from food matrices and 18 reference strains belonging to the P. fluorescens group, which had been previously typed by the multi locus sequence typing method. Subsequently, a subset of reference strains was inoculated in ultra-high temperature milk, and the expression of the aprX gene was evaluated at 22 and 6°C. On the same milk samples, the proteolytic activity was then evaluated through Azocasein and trinitrobenzenesulfonic acid solution assays. Finally, to assess the applicability of the former assay directly on dairy products the proteolityc activity was tested on industrial ricotta samples using the Azocasein assay. These results demonstrate the spread of aprX gene in most strains tested and the applicability of Azocasein assay to monitor the proteolytic activity in dairy products. PMID:28217561

  5. Characterisation of the Thermostable Protease AprX in Strains of Pseudomonas Fluorescens and Impact on the Shelf-life of Dairy Products: Preliminary Results.

    PubMed

    Andreani, Nadia Andrea; Carraro, Lisa; Fasolato, Luca; Balzan, Stefania; Lucchini, Rosaria; Novelli, Enrico; Cardazzo, Barbara

    2016-09-20

    Bacterial proteases are involved in food spoilage and shelf-life reduction. Among the bacterial proteases, a predominant role in spoilage of dairy products seems to be played by the thermostable metallo-protease AprX, which is produced by various strains of Pseudomonas fluorescens. Differences in AprX enzyme activity among different strains were highlighted, but the most proteolytic strains were not identified. In this study, the presence of the aprX gene was evaluated in 69 strains isolated from food matrices and 18 reference strains belonging to the P. fluorescens group, which had been previously typed by the multi locus sequence typing method. Subsequently, a subset of reference strains was inoculated in ultra-high temperature milk, and the expression of the aprX gene was evaluated at 22 and 6°C. On the same milk samples, the proteolytic activity was then evaluated through Azocasein and trinitrobenzenesulfonic acid solution assays. Finally, to assess the applicability of the former assay directly on dairy products the proteolityc activity was tested on industrial ricotta samples using the Azocasein assay. These results demonstrate the spread of aprX gene in most strains tested and the applicability of Azocasein assay to monitor the proteolytic activity in dairy products.

  6. Sulphur flux through the sulphate assimilation pathway is differently controlled by adenosine 5'-phosphosulphate reductase under stress and in transgenic poplar plants overexpressing gamma-ECS, SO, or APR.

    PubMed

    Scheerer, Ursula; Haensch, Robert; Mendel, Ralf R; Kopriva, Stanislav; Rennenberg, Heinz; Herschbach, Cornelia

    2010-01-01

    Sulphate assimilation provides reduced sulphur for the synthesis of cysteine, methionine, and numerous other essential metabolites and secondary compounds. The key step in the pathway is the reduction of activated sulphate, adenosine 5'-phosphosulphate (APS), to sulphite catalysed by APS reductase (APR). In the present study, [(35)S]sulphur flux from external sulphate into glutathione (GSH) and proteins was analysed to check whether APR controls the flux through the sulphate assimilation pathway in poplar roots under some stress conditions and in transgenic poplars. (i) O-Acetylserine (OAS) induced APR activity and the sulphur flux into GSH. (ii) The herbicide Acetochlor induced APR activity and results in a decline of GSH. Thereby the sulphur flux into GSH or protein remained unaffected. (iii) Cd treatment increased APR activity without any changes in sulphur flux but lowered sulphate uptake. Several transgenic poplar plants that were manipulated in sulphur metabolism were also analysed. (i) Transgenic poplar plants that overexpressed the gamma-glutamylcysteine synthetase (gamma-ECS) gene, the enzyme catalysing the key step in GSH formation, showed an increase in sulphur flux into GSH and sulphate uptake when gamma-ECS was targeted to the cytosol, while no changes in sulphur flux were observed when gamma-ECS was targeted to plastids. (ii) No effect on sulphur flux was observed when the sulphite oxidase (SO) gene from Arabidopsis thaliana, which catalyses the back reaction of APR, that is the reaction from sulphite to sulphate, was overexpressed. (iii) When Lemna minor APR was overexpressed in poplar, APR activity increased as expected, but no changes in sulphur flux were observed. For all of these experiments the flux control coefficient for APR was calculated. APR as a controlling step in sulphate assimilation seems obvious under OAS treatment, in gamma-ECS and SO overexpressing poplars. A possible loss of control under certain conditions, that is Cd treatment

  7. Carcinoïde primitif du rein métastasant après 12 ans

    PubMed Central

    Bacha, Dhouha; Lahmar, Ahlem; Gharbi, Lassad; Slama, Sana Ben; Bouraoui, Saadia; Chatti, Samia; Regaya, Sabeh Mzabi

    2016-01-01

    Les carcinoïdes primitifs du rein sont rares avec une centaine de cas rapportés dans la littérature. Sur le plan histologique, il s'agit d'une tumeur bien différenciée dont la morphologie rejoint souvent celle des carcinoïdes dans les autres localisations. Nous rapportons un cas de carcinoïde primitif du rein survenant chez un homme de 41 ans, découvert à la suite de métastases hépatiques. La tumeur était particulière par son architecture tubulo-papillaire, suggérant à tort le diagnostic de carcinome papillaire du rein. Ce diagnostic a été redressé 12 ans après, à la suite de l'apparition d'autres métastases hépatiques, osseuses et pulmonaires. PMID:27217899

  8. 78 FR 14155 - Special Conditions: Learjet Inc., Model LJ-200-1A10 Airplane; Use of Automatic Power Reserve (APR...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-05

    ... Power Reserve (APR), an Automatic Takeoff Thrust Control System (ATTCS), for Go-Around Performance... airplane will have novel or unusual design features associated with utilizing go-around performance credit...: Federal eRegulations Portal: Go to http://www.regulations.gov/ and follow the online instructions for...

  9. Synthesis of Key Points from the OSEP Early Childhood Transition FAQ (SPP/APR Indicators C-8, B-11 and B-12)

    ERIC Educational Resources Information Center

    Diefendorf, M.; Henson, J.; Lucas, A.; Whaley, K.

    2010-01-01

    This document is a synthesis of the key points provided in the Office of Special Education Programs (OSEP) Early Childhood Transition FAQs: SPP/APR indicators C-8 and B-12 released on December 1, 2009. It was developed to assist states with the implementation of effective transition policies and practices. The following is included: (1) Transition…

  10. Effect of surgical castration of bull calves at different stages of maturity with or without analgesia on the acute phase response (APR) and complete blood count (CBC)

    USDA-ARS?s Scientific Manuscript database

    The study objective was to determine if surgical castration at birth or weaning impacts the acute phase response (APR) or complete blood counts (CBC) and whether concurrent administration of an oral analgesic (meloxicam) ameliorates inflammation. Bull calves (n=29) from the University of Arkansas re...

  11. APR-246 (PRIMA-1(MET)) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines.

    PubMed

    Deben, Christophe; Lardon, Filip; Wouters, An; Op de Beeck, Ken; Van den Bossche, Jolien; Jacobs, Julie; Van Der Steen, Nele; Peeters, Marc; Rolfo, Christian; Deschoolmeester, Vanessa; Pauwels, Patrick

    2016-06-01

    APR-246 (PRIMA-1(Met)) is able to bind mutant p53 and restore its normal conformation and function. The compound has also been shown to increase intracellular ROS levels. Importantly, the poly-[ADP-ribose] polymerase-1 (PARP-1) enzyme plays an important role in the repair of ROS-induced DNA damage. We hypothesize that by blocking this repair with the PARP-inhibitor AZD2281 (olaparib), DNA damage would accumulate in the cell leading to massive apoptosis. We observed that APR-246 synergistically enhanced the cytotoxic response of olaparib in TP53 mutant non-small cell lung cancer cell lines, resulting in a strong apoptotic response. In the presence of wild type p53 a G2/M cell cycle block was predominantly observed. NOXA expression levels were significantly increased in a TP53 mutant background, and remained unchanged in the wild type cell line. The combined treatment of APR-246 and olaparib induced cell death that was associated with increased ROS production, accumulation of DNA damage and translocation of p53 to the mitochondria. Out data suggest a promising targeted combination strategy in which the response to olaparib is synergistically enhanced by the addition of APR-246, especially in a TP53 mutant background. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  12. 15 CFR 781.4 - U.S. Government requests for information needed to satisfy the requirements of the APR or the Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 2 2014-01-01 2014-01-01 false U.S. Government requests for information needed to satisfy the requirements of the APR or the Act. 781.4 Section 781.4 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY...

  13. Le don après un décès d'origine cardiocirculatoire au Canada

    PubMed Central

    Shemie, Sam D.; Baker, Andrew J.; Knoll, Greg; Wall, William; Rocker, Graeme; Howes, Daniel; Davidson, Janet; Pagliarello, Joe; Chambers-Evans, Jane; Cockfield, Sandra; Farrell, Catherine; Glannon, Walter; Gourlay, William; Grant, David; Langevin, Stéphan; Wheelock, Brian; Young, Kimberly; Dossetor, John

    2006-01-01

    Résumé Ces recommandations sont le fruit d'un processus multidisciplinaire national ayant duré un an et visant à déterminer si et comment l'on pourrait procéder au don d'organes après un décès d'origine cardiocirculatoire («don après le décès cardiocirculatoire», ou DDC) au Canada. Le forum national organisé en février 2005 a permis aux participants de discuter et d'élaborer des recommandations sur les principes, interventions et pratiques se rapportant au DDC. Les aspects éthiques et juridiques ont été abordés dans les discussions. À la fin du Forum, la majorité des participants ont été favorables à l'implantation de programmes de DDC au Canada. Les participants du Forum ont également convenu qu'il fallait formuler et prôner des valeurs fondamentales pour orienter l'élaboration de programmes et de protocoles basés sur le cadre médical, éthique et juridique établi lors de cette réunion. Même si la possibilité d'un don d'organes et de tissus doit faire partie intégrante des soins de fin de vie, il faut insister sur le fait que le devoir de diligence envers les patients mourants et leurs familles doit demeurer la priorité des équipes soignantes. La complexité et les répercussions profondes du décès sont reconnues et doivent être respectées, de même que les différences personnelles, ethnoculturelles et religieuses face à la mort et au don d'organes. Les décisions d'arrêter le traitement de maintien des fonctions vitales, la prise en charge des derniers moments de la vie et le diagnostic de décès selon des critères cardiocirculatoires doivent être distincts et indépendants des processus de don et transplantation. Ce rapport contient des recommandations destinées aux gestionnaires de program, aux autorités sanitaires régionales et aux instances appelés à élaborer les protocoles de DDC. Les programmes doivent être conçus en fonction des éléments suivants : direction et planification locales, éducation et

  14. Forme précoce du syndrome de Wilkie: complication rare de la chirurgie pour scoliose à propos d’un cas et revue de la littérature

    PubMed Central

    Traore, Mamadou Mour; Leye, Pape Alassane; Bah, Mamadou Diawo; Kinkpe, Charles Valérie Alain; Ndiaye, Pape Ibrahima; Daffe, Mohamed; Toure, Alpha Omar; Kane, Oumar

    2016-01-01

    Le syndrome de la pince aorto-mésentérique est une complication rare pouvant survenir après une correction chirurgicale de scoliose. Les phénomènes de traction verticale de l’artère mésentérique et le rétrécissement de l’angle aorto-mésentérique lors de la correction sont à l’origine de ce syndrome par compression du troisième duodénum. Nous rapportons ici l’observation d’un cas précoce de syndrome de la pince aorto-mésentérique secondaire à une correction chirurgicale d’une scoliose idiopathique chez une fille. Une jeune fille opérée d’une arthrodèse vertébrale postérieure pour une scoliose idiopathique avait présenté au troisième jour postopératoire des vomissements incoercibles avec arrêt des matières et des gaz. Le scanner abdominal réalisé en urgence avait permis le diagnostic d’un syndrome de l’artère mésentérique supérieure. La prise en charge consistait à une mise au repos du tube digestif associé à une nutrition parentérale précoce et une correction des déséquilibres hydroélectrolytiques. Devant l’absence d’amélioration clinique, l’indication opératoire fut posée. L’évolution a été favorable avec des suites opératoires simples et une reprise alimentaire orale à quatrième jour, une sortie à domicile au septième jour postopératoire.Les facteurs favorisants sont les sujets jeunes, de morphotype longiligne avec un faible IMC inférieur à 18.Les signes scannographiques sont une dilatation gastrique importante avec un arrêt net au niveau de 3ème duodénum. La prise en charge est multidisciplinaire étant médicale d’abord et chirurgicale en cas d’échec. Une meilleure connaissance des facteurs prédictifs d’échec du traitement médical permettrait de réduire la durée de séjour hospitalier. PMID:28292053

  15. APR-246/PRIMA-1(MET) rescues epidermal differentiation in skin keratinocytes derived from EEC syndrome patients with p63 mutations.

    PubMed

    Shen, Jinfeng; van den Bogaard, Ellen H; Kouwenhoven, Evelyn N; Bykov, Vladimir J N; Rinne, Tuula; Zhang, Qiang; Tjabringa, Geuranne S; Gilissen, Christian; van Heeringen, Simon J; Schalkwijk, Joost; van Bokhoven, Hans; Wiman, Klas G; Zhou, Huiqing

    2013-02-05

    p53 and p63 share extensive sequence and structure homology. p53 is frequently mutated in cancer, whereas mutations in p63 cause developmental disorders manifested in ectodermal dysplasia, limb defects, and orofacial clefting. We have established primary adult skin keratinocytes from ectrodactyly, ectodermal dysplasia, and cleft lip/palate (EEC) syndrome patients with p63 mutations as an in vitro human model to study the disease mechanism in the skin of EEC patients. We show that these patient keratinocytes cultured either in submerged 2D cultures or in 3D skin equivalents have impaired epidermal differentiation and stratification. Treatment of these patient keratinocytes with the mutant p53-targeting compound APR-246/PRIMA-1(MET) (p53 reactivation and induction of massive apoptosis) that has been successfully tested in a phase I/II clinical trial in cancer patients partially but consistently rescued morphological features and gene expression during epidermal stratification in both 2D and 3D models. This rescue coincides with restoration of p63 target-gene expression. Our data show that EEC patient keratinocytes with p63 mutations can be used for characterization of the abnormal molecular circuitry in patient skin and may open possibilities for the design of novel pharmacological treatment strategies for patients with mutant p63-associated developmental abnormalities.

  16. Régulation de la production, par des cellules endothéliales, de cytokines pro-inflammatoires après irradiation

    NASA Astrophysics Data System (ADS)

    van der Meeren, A.; Lafont, H.; Mathé, D.

    1998-04-01

    Gamma irradiation leads to an increased production of interleukin- (IL)-6 and IL-8 by human endothelial cells. In order to regulate the radio-induced production of these pro-inflammatory cytokines, we used the immunoregulatory cytokines IL-4 and IL-10. These agents were added either before or after a 10 Gy-irradiation. Our results show that it is possible to decrease the radio-induced production of IL-6 and IL-8 with the use of IL-4 and IL-10. Differences in the intensity of the response have been observed according to the time of treatment. The anti-inflammatory potential of both IL-4 and IL-10 was more pronounced when added after irradiation. Après irradiation gamma, des cellules endothéliales humaines ont une production accrue des interleukines (IL-) -6 et -8. Dans le but de réguler la production de ces cytokines pro-inflammatoires, nous avons utilisé des cytokines dites anti-inflammatoires, l'IL-4 et l'IL-10. Ces agents ont été ajoutés soit avant soit après une irradiation de 10Gy. Nos résultats montrent qu'il est possible de diminuer les productions radio-induites d'IL-6 et d'IL-8 par l'IL-4 et l'IL-10. Des différences dans l'intensité de la réponse ont toutefois été observées selon que l'IL-4 ou l'IL-10 ont été ajoutées avant ou après irradiation; leur efficacité anti-inflammatoire étant plus marquée lorsque les cytokines sont ajoutées après l'irradiation.

  17. Antiviral activity of the plant extracts from Thuja orientalis, Aster spathulifolius, and Pinus thunbergii against influenza virus A/PR/8/34.

    PubMed

    Won, Ji-Na; Lee, Seo-Yong; Song, Dae-sub; Poo, Haryoung

    2013-01-01

    Influenza viruses cause significant morbidity and mortality in humans through epidemics or pandemics. Currently, two classes of anti-influenza virus drugs, M2 ion-channel inhibitors (amantadin and rimantadine) and neuraminidase inhibitors (oseltamivir and zanamivir), have been used for the treatment of the influenza virus infection. Since the resistance to these drugs has been reported, the development of a new antiviral agent is necessary. In this study, we examined the antiviral efficacy of the plant extracts against the influenza A/PR/8/34 infection. In vitro, the antiviral activities of the plant extracts were investigated using the cell-based screening. Three plant extracts, Thuja orientalis, Aster spathulifolius, and Pinus thunbergii, were shown to induce a high cell viability rate after the infection with the influenza A/PR/8/34 virus. The antiviral activity of the plant extracts also increased as a function of the concentration of the extracts and these extracts significantly reduced the visible cytopathic effect caused by virus infections. Furthermore, the treatment with T. orientalis was shown to have a stronger inhibitory effect than that with A. spathulifolius or P. thunbergii. These results may suggest that T. orientalis has anti-influenza A/PR/8/34 activity.

  18. PRIMA-1Met/APR-246 displays high antitumor activity in multiple myeloma by induction of p73 and Noxa.

    PubMed

    Saha, Manujendra N; Jiang, Hua; Yang, Yijun; Reece, Donna; Chang, Hong

    2013-11-01

    Targeting p53 by the small-molecule PRIMA-1(Met)/APR-246 has shown promising preclinical activity in various cancer types. However, the mechanism of PRIMA-1(Met)-induced apoptosis is not completely understood and its effect on multiple myeloma cells is unknown. In this study, we evaluated antitumor effect of PRIMA-1(Met) alone or its combination with current antimyeloma agents in multiple myeloma cell lines, patient samples, and a mouse xenograft model. Results of our study showed that PRIMA-1(Met) decreased the viability of multiple myeloma cells irrespective of p53 status, with limited cytotoxicity toward normal hematopoietic cells. Treatment of multiple myeloma cells with PRIMA-1(Met) resulted in induction of apoptosis, inhibition of colony formation, and migration. PRIMA-1(Met) restored wild-type conformation of mutant p53 and induced activation of p73 upregulating Noxa and downregulating Mcl-1 without significant modulation of p53 level. siRNA-mediated silencing of p53 showed a little effect on apoptotic response of PRIMA-1(Met), whereas knockdown of p73 led to substantial attenuation of apoptotic activity in multiple myeloma cells, indicating that PRIMA-1(Met)-induced apoptosis is, at least in part, p73-dependent. Importantly, PRIMA-1(Met) delayed tumor growth and prolonged survival of mice bearing multiple myeloma tumor. Furthermore, combined treatment of PRIMA-1(Met) with dexamethasone or doxorubicin displayed synergistic effects in both multiple myeloma cell lines and primary multiple myeloma samples. Consistent with our in vitro observations, cotreatment with PRIMA-1(Met) and dexamethasone resulted in enhanced antitumor activity in vivo. Our study for the first time shows antimyeloma activity of PRIMA-1(Met) and provides the rationale for its clinical evaluation in patients with multiple myeloma, including the high-risk group with p53 mutation/deletion.

  19. Activity of Melaleuca alternifolia (tea tree) oil on Influenza virus A/PR/8: study on the mechanism of action.

    PubMed

    Garozzo, A; Timpanaro, R; Stivala, A; Bisignano, G; Castro, A

    2011-01-01

    Our previous study demonstrated that Melaleuca alternifolia (tea tree) oil (TTO) had an interesting antiviral activity against Influenza A in MDCK cells. In fact, when we tested TTO and some of its components, we found that TTO had an inhibitory effect on influenza virus replication at doses below the cytotoxic dose; terpinen-4-ol, terpinolene, and alfa-terpineol were the main active components. The aim of this study was to investigate the mechanism of action of TTO and its active components against Influenza A/PR/8 virus subtype H1N1 in MDCK cells. None of the test compounds showed virucidal activity nor any protective action for the MDCK cells. Thus, the effect of TTO and its active components on different steps of the replicative cycle of influenza virus was studied by adding the test compounds at various times after infection. These experiments revealed that viral replication was significantly inhibited if TTO was added within 2h of infection, indicating an interference with an early step of the viral replicative cycle of influenza virus. The influence of the compound on the virus adsorption step, studied by the infective center assay, indicated that TTO did not interfere with cellular attachment of the virus. TTO did not inhibit influenza virus neuraminidase activity, as shown by the experiment measuring the amount of 4-methylumbelliferone, cleaved by the influenza virus neuraminidase from the fluorogenic substrate 2'-O-(4-methylumbelliferyl)-N-acetylneuraminic acid. The effect of TTO on acidification of cellular lysosomes was studied by vital staining with acridine orange using bafilomycin A1 as positive control. The treatment of cells with 0.01% (v/v) of TTO at 37°C for 4h before staining inhibited the acridine orange accumulation in acid cytoplasmic vesicles, indicating that TTO could inhibit viral uncoating by an interference with acidification of intralysosomal compartment.

  20. Molecular Analysis of the Diversity of Sulfate-Reducing and Sulfur-Oxidizing Prokaryotes in the Environment, Using aprA as Functional Marker Gene▿ †

    PubMed Central

    Meyer, Birte; Kuever, Jan

    2007-01-01

    The dissimilatory adenosine-5′-phosposulfate reductase is a key enzyme of the microbial sulfate reduction and sulfur oxidation processes. Because the alpha- and beta-subunit-encoding genes, aprBA, are highly conserved among sulfate-reducing and sulfur-oxidizing prokaryotes, they are most suitable for molecular profiling of the microbial community structure of the sulfur cycle in environment. In this study, a new aprA gene-targeting assay using a combination of PCR and denaturing gradient gel electrophoresis is presented. The screening of sulfate-reducing and sulfur-oxidizing reference strains as well as the analyses of environmental DNA from diverse habitats (e.g., microbial mats, invertebrate tissue, marine and estuarine sediments, and filtered hydrothermal water) by the new primer pair revealed an improved microbial diversity coverage and less-pronounced template-to-PCR product bias in direct comparison to those of the previously published primer set (B. Deplancke, K. R. Hristova, H. A. Oakley, V. J. McCracken, R. Aminov, R. I. Mackie, and H. R. Gaskins, Appl. Environ. Microbiol. 66:2166-2174, 2000). The concomitant molecular detection of sulfate-reducing and sulfur-oxidizing prokaryotes was confirmed. The new assay was applied in comparison with the 16S rRNA gene-based analysis to investigate the microbial diversity of the sulfur cycle in sediment, seawater, and manganese crust samples from four study sites in the area of the Lesser Antilles volcanic arc, Caribbean Sea (Caribflux project). The aprA gene-based approach revealed putative sulfur-oxidizing Alphaproteobacteria of chemolithoheterotrophic lifestyle to have been abundant in the nonhydrothermal sediment and water column. In contrast, the sulfur-based microbial community that inhabited the surface of the volcanic manganese crust was more complex, consisting predominantly of putative chemolithoautotrophic sulfur oxidizers of the Betaproteobacteria and Gammaproteobacteria. PMID:17921272

  1. Peut-on réaliser une analgésie péridurale après un blood patch récent?

    PubMed Central

    Chkoura, Khalid; Kechna, Hicham; Loutid, Jaouad; Ouzad, Omar; Hachimi, Moulay Ahmed; Hannafi, Sidi Mohamed

    2015-01-01

    Le blood patch constitue le traitement de référence du syndrome post ponction lombaire. Son efficacité a été démontrée par plusieurs essais randomisés comparant le BPE aux mesures conservatrices et au placebo. Il consiste en l'injection d'une quantité de sang autologue dans l'espace péridurale afin d'obturer la brèche dure-mérienne. La réalisation d'une analgésie péridurale après antécédent de blood patch est possible, malgré la persistance de questions sur les délais de retour à la normal de l'espace péridurale. Nous rapportons un cas où une analgésie péridurale a été réalisée avec succès trois semaines après un blood patch. PMID:26600909

  2. Application of the response surface methodology for optimizing the activity of an aprE-driven gene expression system in Bacillus subtilis.

    PubMed

    El-Helow, E R; Abdel-Fattah, Y R; Ghanem, K M; Mohamad, E A

    2000-10-01

    The major targets for improvement of recombinant expression systems in microbial cells are gene dosage, transcriptional control machinery and, to some extent, translation. Here we show that optimization of fermentation conditions by applying statistically designed, multifactorial experiments offers an additional method for potential enhancement of gene expression systems. A chromosomally encoded fusion between the Bacillus subtilis aprE regulatory region and the E. coli lacZ gene carried by the B. subtilis host cells was used. The 2 x SG sporulation medium was used as a basal medium. Among the 11 fermentation factors we examined, the most significant variables influencing beta-galactosidase expression were statistically elucidated for optimization and included peptone, MgSO4.7H2O, and KCl. The optimum concentrations of these variables were predicted by using a second-order polynomial model fitted to the results obtained by applying the Box-Behnken design, a response surface method. Calculated optimum concentrations were predicted to confer a maximum yield of 2,423.5 beta-galactosidase specific activity units. A verification experiment performed under optimal conditions yielded 96% of the predicted specific activity value with an increase by a factor of almost 5 compared with the results obtained under basal conditions.

  3. Real-Time PCR Quantification and Diversity Analysis of the Functional Genes aprA and dsrA of Sulfate-Reducing Prokaryotes in Marine Sediments of the Peru Continental Margin and the Black Sea.

    PubMed

    Blazejak, Anna; Schippers, Axel

    2011-01-01

    Sulfate-reducing prokaryotes (SRP) are ubiquitous and quantitatively important members in many ecosystems, especially in marine sediments. However their abundance and diversity in subsurface marine sediments is poorly understood. In this study, the abundance and diversity of the functional genes for the enzymes adenosine 5'-phosphosulfate reductase (aprA) and dissimilatory sulfite reductase (dsrA) of SRP in marine sediments of the Peru continental margin and the Black Sea were analyzed, including samples from the deep biosphere (ODP site 1227). For aprA quantification a Q-PCR assay was designed and evaluated. Depth profiles of the aprA and dsrA copy numbers were almost equal for all sites. Gene copy numbers decreased concomitantly with depth from around 10(8)/g sediment close to the sediment surface to less than 10(5)/g sediment at 5 mbsf. The 16S rRNA gene copy numbers of total bacteria were much higher than those of the functional genes at all sediment depths and used to calculate the proportion of SRP to the total Bacteria. The aprA and dsrA copy numbers comprised in average 0.5-1% of the 16S rRNA gene copy numbers of total bacteria in the sediments up to a depth of ca. 40 mbsf. In the zone without detectable sulfate in the pore water from about 40-121 mbsf (Peru margin ODP site 1227), only dsrA (but not aprA) was detected with copy numbers of less than 10(4)/g sediment, comprising ca. 14% of the 16S rRNA gene copy numbers of total bacteria. In this zone, sulfate might be provided for SRP by anaerobic sulfide oxidation. Clone libraries of aprA showed that all isolated sequences originate from SRP showing a close relationship to aprA of characterized species or form a new cluster with only distant relation to aprA of isolated SRP. For dsrA a high diversity was detected, even up to 121 m sediment depth in the deep biosphere.

  4. Real-Time PCR Quantification and Diversity Analysis of the Functional Genes aprA and dsrA of Sulfate-Reducing Prokaryotes in Marine Sediments of the Peru Continental Margin and the Black Sea

    PubMed Central

    Blazejak, Anna; Schippers, Axel

    2011-01-01

    Sulfate-reducing prokaryotes (SRP) are ubiquitous and quantitatively important members in many ecosystems, especially in marine sediments. However their abundance and diversity in subsurface marine sediments is poorly understood. In this study, the abundance and diversity of the functional genes for the enzymes adenosine 5′-phosphosulfate reductase (aprA) and dissimilatory sulfite reductase (dsrA) of SRP in marine sediments of the Peru continental margin and the Black Sea were analyzed, including samples from the deep biosphere (ODP site 1227). For aprA quantification a Q-PCR assay was designed and evaluated. Depth profiles of the aprA and dsrA copy numbers were almost equal for all sites. Gene copy numbers decreased concomitantly with depth from around 108/g sediment close to the sediment surface to less than 105/g sediment at 5 mbsf. The 16S rRNA gene copy numbers of total bacteria were much higher than those of the functional genes at all sediment depths and used to calculate the proportion of SRP to the total Bacteria. The aprA and dsrA copy numbers comprised in average 0.5–1% of the 16S rRNA gene copy numbers of total bacteria in the sediments up to a depth of ca. 40 mbsf. In the zone without detectable sulfate in the pore water from about 40–121 mbsf (Peru margin ODP site 1227), only dsrA (but not aprA) was detected with copy numbers of less than 104/g sediment, comprising ca. 14% of the 16S rRNA gene copy numbers of total bacteria. In this zone, sulfate might be provided for SRP by anaerobic sulfide oxidation. Clone libraries of aprA showed that all isolated sequences originate from SRP showing a close relationship to aprA of characterized species or form a new cluster with only distant relation to aprA of isolated SRP. For dsrA a high diversity was detected, even up to 121 m sediment depth in the deep biosphere. PMID:22203820

  5. Monoclinically distorted perovskites, A{sub 2}ZnTiO{sub 6} (A=Pr, Gd): Rietveld refinement, and dielectric studies

    SciTech Connect

    Das, Nibedita; Nath, Masood A.; Thakur, Gohil S.; Thirumal, M.; Ganguli, Ashok K.

    2015-09-15

    Double perovskite related oxide A{sub 2}ZnTiO{sub 6}A=Pr, Gd were synthesized by the solid state reaction method at 1523 K. The structure and microstructure of the compounds were studied by X-ray, SAED and FESEM. Rietveld refinement of the powder X-ray analysis shows that the compounds crystallizes in monoclinic space group P2{sub 1}/n (a{sup +}b{sup −}b{sup −}) with unit cell parameter √2a{sub p}×√2a{sub p}×2a{sub p} (a=5.5026(1) Å, b=5.6305(1) Å, c=7.8149(1) Å, β=90.02(1)° for Pr{sub 2}ZnTiO{sub 6} and a=5.3621(1) Å, b=5.6565(2) Å, c=7.6779(2) Å and β=90.264(2)° for Gd{sub 2}ZnTiO{sub 6}. Electron diffraction study confirms P2{sub 1}/n symmetry of the oxides. The monoclinic distortion is larger in Gd{sub 2}ZnTiO{sub 6} than Pr{sub 2}ZnTiO{sub 6} which is associated with the tolerance factor and the tilting angle of ZnO{sub 6} and TiO{sub 6} octahedra (ϕ=13.64° for Pr{sub 2}ZnTiO{sub 6} and 16.51° for Gd{sub 2}ZnTiO{sub 6}). The compounds are highly ordered. The charge and size difference between B site cations are the driving force for the ordering of the B′O{sub 6} and B″O{sub 6} octahedra. Pr{sub 2}ZnTiO{sub 6} shows a dielectric constant of 27 and dielectric loss of 0.003 while Gd{sub 2}ZnTiO{sub 6} has a dielectric constant of 17 and dielectric loss of 0.005 measured at 1 MHz. - Graphical abstract: Synthesis of new double perovskite dielectric material with very low dielectric loss. - Highlights: • Synthesis of new monoclinically distorted double perovskite (Pr{sub 2}ZnTiO{sub 6}). • Synthesis of monoclinically distorted double perovskite (Gd{sub 2}ZnTiO{sub 6}). • Selected area electron diffraction study of A{sub 2}ZnTiO{sub 6} (A=Pr, Gd). • Study of dielectric properties of A{sub 2}ZnTiO{sub 6} (A=Pr, Gd)

  6. The LasB Elastase of Pseudomonas aeruginosa Acts in Concert with Alkaline Protease AprA To Prevent Flagellin-Mediated Immune Recognition.

    PubMed

    Casilag, Fiordiligie; Lorenz, Anne; Krueger, Jonas; Klawonn, Frank; Weiss, Siegfried; Häussler, Susanne

    2015-10-26

    The opportunistic pathogen Pseudomonas aeruginosa is capable of establishing severe and persistent infections in various eukaryotic hosts. It encodes a wide array of virulence factors and employs several strategies to evade immune detection. In the present study, we screened the Harvard Medical School transposon mutant library of P. aeruginosa PA14 for bacterial factors that modulate interleukin-8 responses in A549 human airway epithelial cells. We found that in addition to the previously identified alkaline protease AprA, the elastase LasB is capable of degrading exogenous flagellin under calcium-replete conditions and prevents flagellin-mediated immune recognition. Our results indicate that the production of two proteases with anti-flagellin activity provides a failsafe mechanism for P. aeruginosa to ensure the maintenance of protease-dependent immune-modulating functions.

  7. Structure and magnetic properties of new Be-substituted langasites A3Ga3Ge2BeO14 (A=Pr, Nd, and Sm)

    NASA Astrophysics Data System (ADS)

    Sharma, A. Z.; Silverstein, H. J.; Hallas, A. M.; Luke, G. M.; Wiebe, C. R.

    2016-01-01

    Langasites have been studied extensively in past for their functional properties and use in telecommunication. A thorough understanding of their ground state is limited by the difficulty in synthesizing new members belonging to this series due to the formation of competing phases such as the garnets. Three magnetic langasites A3Ga3Ge2BeO14 (A=Pr, Nd, and Sm) and a non-magnetic lattice standard La3Ga3Ge2BeO14 were synthesized using the ceramic method. These were further characterized by X-ray diffraction, magnetization, magnetic susceptibility and heat capacity measurements. All three langasites exhibit net antiferromagnetic interactions at low temperatures and no evidence of long range magnetic ordering was observed down to 0.350 K.

  8. The LasB Elastase of Pseudomonas aeruginosa Acts in Concert with Alkaline Protease AprA To Prevent Flagellin-Mediated Immune Recognition

    PubMed Central

    Casilag, Fiordiligie; Lorenz, Anne; Krueger, Jonas; Klawonn, Frank; Weiss, Siegfried

    2015-01-01

    The opportunistic pathogen Pseudomonas aeruginosa is capable of establishing severe and persistent infections in various eukaryotic hosts. It encodes a wide array of virulence factors and employs several strategies to evade immune detection. In the present study, we screened the Harvard Medical School transposon mutant library of P. aeruginosa PA14 for bacterial factors that modulate interleukin-8 responses in A549 human airway epithelial cells. We found that in addition to the previously identified alkaline protease AprA, the elastase LasB is capable of degrading exogenous flagellin under calcium-replete conditions and prevents flagellin-mediated immune recognition. Our results indicate that the production of two proteases with anti-flagellin activity provides a failsafe mechanism for P. aeruginosa to ensure the maintenance of protease-dependent immune-modulating functions. PMID:26502908

  9. The destiny of an unacknowledged trauma: the deferred retroactive effect of après-coup in the hidden Jewish children of wartime Belgium.

    PubMed

    Fohn, Adeline; Heenen-Wolff, Susann

    2011-02-01

    For almost 45 years, the experience of Jewish children who were hidden during World War II was considered to be of little importance, particularly with respect to what had taken place in the concentration camps. Their very history was ignored in the many accounts of the Holocaust. It was only at the end of the 1980s that their experience began to be thought of as potentially traumatic. In this paper, the authors report on their psychoanalytical research project concerning the psychological outcomes of those experiences that had remained concealed for such an extraordinarily long latency period. The results are based on the analysis of 60 accounts and on psychoanalytically-oriented group work. The authors show that the trauma experienced by those hidden children was triggered by the retroactive effect of a deferred action [après-coup].

  10. The SAMPL5 host-guest challenge: computing binding free energies and enthalpies from explicit solvent simulations by the attach-pull-release (APR) method

    NASA Astrophysics Data System (ADS)

    Yin, Jian; Henriksen, Niel M.; Slochower, David R.; Gilson, Michael K.

    2017-01-01

    The absolute binding free energies and binding enthalpies of twelve host-guest systems in the SAMPL5 blind challenge were computed using our attach-pull-release (APR) approach. This method has previously shown good correlations between experimental and calculated binding data in retrospective studies of cucurbit[7]uril (CB7) and β-cyclodextrin (βCD) systems. In the present work, the computed binding free energies for host octa acid (OA or OAH) and tetra-endo-methyl octa-acid (TEMOA or OAMe) with guests are in good agreement with prospective experimental data, with a coefficient of determination (R2) of 0.8 and root-mean-squared error of 1.7 kcal/mol using the TIP3P water model. The binding enthalpy calculations achieve moderate correlations, with R2 of 0.5 and RMSE of 2.5 kcal/mol, for TIP3P water. Calculations using the newly developed OPC water model also show good performance. Furthermore, the present calculations semi-quantitatively capture the experimental trend of enthalpy-entropy compensation observed, and successfully predict guests with the strongest and weakest binding affinity. The most populated binding poses of all twelve systems, based on clustering analysis of 750 ns molecular dynamics (MD) trajectories, were extracted and analyzed. Computational methods using MD simulations and explicit solvent models in a rigorous statistical thermodynamic framework, like APR, can generate reasonable predictions of binding thermodynamics. Especially with continuing improvement in simulation force fields, such methods hold the promise of making substantial contributions to hit identification and lead optimization in the drug discovery process.

  11. Gangrène de la main après injection accidentelle intra artérielle de floxacilline: à propos d’un cas

    PubMed Central

    Salama, Tarik; Aghoutane, El Mohtadi; Fezzazi, Rédouane El

    2016-01-01

    La floxacilline appartient à la classe des pénicillines bêta lactames. Dans notre contexte elle est très utilisée pour lutter contre les infections à germes Gram positif dont le staphylocoque doré. Cependant son utilisation doit être très prudente car elle n’est pas dénuée de complications. Nous rapportons l’observation d’un garçon de 6 ans opéré pour fracture de l’humérus. L’enfant a été mis sous floxacilline injectable après suspicion d’une infection sur matériel 2 mois après son opération. Le lendemain du début de l’antibiothérapie, l’enfant a présenté une ischémie aigue de la main droite. Il nous a alors été adressé pour prise en charge. Les explorations ont objectivé une obstruction de l’artère radiale. Une aponévrotomie de décharge a été réalisée et une héparinothérapie post opératoire a été démarrée. L’évolution a été marquée par une gangrène de toute la main. A travers cette observation nous voulons sensibiliser le personnel soignant sur le risque de survenue de cette complication désastreuse, et les mesures à prendre pour la prévenir. PMID:28293337

  12. Complete Protection against Influenza Virus H1N1 Strain A/PR/8/34 Challenge in Mice Immunized with Non-Adjuvanted Novirhabdovirus Vaccines

    PubMed Central

    Rouxel, Ronan N.; Mérour, Emilie; Biacchesi, Stéphane; Brémont, Michel

    2016-01-01

    Novirhabdoviruses like Viral Hemorrhagic Septicemia Virus (VHSV) and Infectious Hematopoietic Necrosis Virus (IHNV) are fish-infecting Rhabdoviruses belonging to the Mononegavirales order. By reverse genetics, we previously showed that a recombinant VHSV expressing the West Nile Virus (WNV) E glycoprotein could serve as a vaccine platform against WNV. In the current study, we aimed to evaluate the potential of the Novirhabdovirus platform as a vaccine against influenza virus. Recombinant Novirhabdoviruses, rVHSV-HA and rIHNV-HA, expressing at the viral surface the hemagglutinin HA ectodomain were generated and used to immunized mice. We showed that mice immunized with either, rVHSV-HA or rIHNV-HA, elicited a strong neutralizing antibody response against influenza virus. A complete protection was conferred to the immunized mice when challenged with a lethal dose of influenza H1N1 A/PR/8/34 virus. Furthermore we showed that although acting as inert antigen in mice, since naturally inactivated over 20°C, mice immunized with rVHSV-HA or rIHNV-HA in the absence of adjuvant were also completely protected from a lethal challenge. Novirhabdoviruses platform are of particular interest as vaccines for mammals since they are cost effective to produce, relatively easy to generate and very effective to protect immunized animals. PMID:27711176

  13. Activation of CK1ε by PP2A/PR61ε is required for the initiation of Wnt signaling

    PubMed Central

    Curto, J; Padilla, M; Villarroel, A; Yang, J; de Herreros, AG; Duñach, M

    2016-01-01

    Canonical Wnt signaling induces the stabilization of β-catenin, its translocation to the nucleus and the activation of target promoters. This pathway is initiated by the binding of Wnt ligands to the Frizzled receptor, the association of the LRP5/6 coreceptor and the formation of a complex comprising Dvl-2, Axin and protein kinases CK1α, ε, γ and GSK3. Among these, activation of CK1ε, constitutively bound to LRP5/6 through p120-catenin, is required for the association of the rest of the components. We describe here that CK1ε is activated by the PP2A/PR61ε phosphatase. Binding of Wnt ligands promotes the interaction of LRP5/6-associated CK1ε with Frizzled-bound PR61ε regulatory subunit, facilitating the access of PP2A catalytic subunit to CK1ε and its activation, what enables the recruitment of Dvl-2 to the receptor complex and the initiation of the Wnt pathway. Our results uncover the mechanism of activation of the canonical Wnt pathway by its ligands. PMID:27321178

  14. Fistule artério-urétérale après une pelvectomie antérieure : Complication rare et grave

    PubMed Central

    Zine el abidine, Mohamed Hosni; Hmida, Wissem; Slama, Adel; Hidoussi, Adnene; Jaidane, Mehdi; Ben Sorba, Nabil; Mosbah, Ali Fawzi

    2012-01-01

    Résumé La fistule artério-urétérale (FAU), qui survient immédiatement après une cystectomie, est une complication exceptionnelle et grave. De nos jours, seulement quelques cas sporadiques ont été signalés dans la littérature. Elle se manifeste presque exclusivement par une hématurie brutale, massive et intermittente pouvant être à l’origine d’une instabilité hémodynamique menaçant le pronostic vital du patient à court terme. Son diagnostic doit être fait sans retard. Les explorations radiologiques restent peu spécifiques et peu sensibles et se basent essentiellement sur l’artériographie. Le traitement est non codifié selon l’état général du patient et surtout de la nature de la fistule. Nous décrivons un cas de FAU faisant suite à une pelvectomie antérieure et nous discuterons à l’aide d’une revue de la littérature les aspects diagnostiques, thérapeutiques et pronostiques de cette complication. PMID:23283100

  15. Impaired epithelial differentiation of induced pluripotent stem cells from ectodermal dysplasia-related patients is rescued by the small compound APR-246/PRIMA-1MET.

    PubMed

    Shalom-Feuerstein, Ruby; Serror, Laura; Aberdam, Edith; Müller, Franz-Josef; van Bokhoven, Hans; Wiman, Klas G; Zhou, Huiqing; Aberdam, Daniel; Petit, Isabelle

    2013-02-05

    Ectodermal dysplasia is a group of congenital syndromes affecting a variety of ectodermal derivatives. Among them, ectrodactyly, ectodermal dysplasia, and cleft lip/palate (EEC) syndrome is caused by single point mutations in the p63 gene, which controls epidermal development and homeostasis. Phenotypic defects of the EEC syndrome include skin defects and limbal stem-cell deficiency. In this study, we designed a unique cellular model that recapitulated major embryonic defects related to EEC. Fibroblasts from healthy donors and EEC patients carrying two different point mutations in the DNA binding domain of p63 were reprogrammed into induced pluripotent stem cell (iPSC) lines. EEC-iPSC from both patients showed early ectodermal commitment into K18(+) cells but failed to further differentiate into K14(+) cells (epidermis/limbus) or K3/K12(+) cells (corneal epithelium). APR-246 (PRIMA-1(MET)), a small compound that restores functionality of mutant p53 in human tumor cells, could revert corneal epithelial lineage commitment and reinstate a normal p63-related signaling pathway. This study illustrates the relevance of iPSC for p63 related disorders and paves the way for future therapy of EEC.

  16. Anti-leukaemic effects induced by APR-246 are dependent on induction of oxidative stress and the NFE2L2/HMOX1 axis that can be targeted by PI3K and mTOR inhibitors in acute myeloid leukaemia cells.

    PubMed

    Ali, Dina; Mohammad, Dara K; Mujahed, Huthayfa; Jonson-Videsäter, Kerstin; Nore, Beston; Paul, Christer; Lehmann, Sören

    2016-07-01

    The small molecule APR-246 (PRIMA-1(MET) ) is a novel drug that restores the activity of mutated and unfolded TP53 protein. However, the mechanisms of action and potential off-target effects are not fully understood. Gene expression profiling in TP53 mutant KMB3 acute myeloid leukaemia (AML) cells showed that genes which protected cells from oxidative stress to be the most up-regulated. APR-246 exposure also induced reactive oxygen species (ROS) formation and depleted glutathione in AML cells. The genes most up-regulated by APR-246, confirmed by quantitative real time polymerase chain reaction, were heme oxygenase-1 (HMOX1, also termed HO-1), SLC7A11 and RIT1. Up-regulation of HMOX1, a key regulator of cellular response to ROS, was independent of TP53 mutational status. NFE2L2 (also termed Nrf2), a master regulator of HMOX1 expression, showed transcriptional up-regulation and nuclear translocation by APR-246. Down-regulation of NFE2L2 by siRNA in AML cells significantly increased the antitumoural effects of APR-246. The PI3K inhibitor wortmannin and the mTOR inhibitor rapamycin inhibited APR-246-induced nuclear translocation of NFE2L2 and counteracted the protective cellular responses to APR-246, resulting in synergistic cell killing together with APR-246. In conclusion, ROS induction is important for antileukaemic activities of APR-246 and inhibiting the protective response of the Nrf-2/HMOX1 axis using PI3K inhibitors, enhances the antileukaemic effects. © 2016 John Wiley & Sons Ltd.

  17. A scaling study of the natural circulation flow of the ex-vessel core catcher cooling system of EU-APR1400 for designing a scale-down test facility for design verification

    SciTech Connect

    Rhee, B. W.; Ha, K. S.; Park, R. J.; Song, J. H.; Revankar, S. T.

    2012-07-01

    In this paper a scaling study on the steady state natural circulation flow along the flow path of the ex vessel core catcher cooling system of EU-APR1400 is described, and the scaling criteria for reproducing the same steady state thermalhydraulic characteristics of the natural circulation flow as a prototype core catcher cooling system in the scale-down test facility are derived in terms of the down-comer pipe diameter and orifice resistance. (authors)

  18. Many variable region genes are utilized in the antibody response of BALB/c mice to the influenza virus A/PR/8/34 hemagglutinin.

    PubMed

    Caton, A J; Stark, S E; Kavaler, J; Staudt, L M; Schwartz, D; Gerhard, W

    1991-09-01

    We have examined how many different H chain variable (VH) and kappa-chain variable (Vk) germ-line genes are used in the antibody response to the influenza virus A/PR/8/34 hemagglutinin (PR8 HA), and have assessed how the expression of individual VH and/or Vk genes contributes to the generation of specificity for the HA. A panel of 51 hybridoma antibodies that recognize two antigenic regions on the HA were compared for the sequence of their Ig H and L chain V regions. The hybridomas were obtained from 28 individual BALB/c mice that had been immunized with PR8 under a variety of primary and secondary response immunization protocols. The degree and pattern of sequence similarity suggests that 29 different VH genes drawn from seven different VH gene families, and 25 different Vk genes drawn from 12 different Vk gene families were used in this panel. Based on current estimates of the total numbers of VH and Vk genes in the mouse, this suggests that between 2.5 and 10% of the entire VH and Vk germ-line repertoires were used by these hybridomas. Despite this extensive diversity, some V genes were repetitively identified among these hybridomas, and were most often expressed in the context of specific VH/Vk combinations. Because antibodies that used identical VH/Vk combinations also usually displayed similar reactivity patterns with a panel of mutant viruses, this indicates that VH/Vk pairing can be important in establishing the specificity of antibodies for the HA.

  19. Coadministration of Hedera helix L. Extract Enabled Mice to Overcome Insufficient Protection against Influenza A/PR/8 Virus Infection under Suboptimal Treatment with Oseltamivir

    PubMed Central

    Shim, Aeri; Lee, Bo-Ra; Kwon, Bo-Eun; Song, Hyuk-Hwan; Kim, Yeon-Jeong; Chang, Sun-Young; Jeong, Hyeon Gun; Kim, Jong Geal; Seo, Sang-Uk; Kim, HyunPyo; Kwon, YongSoo; Ko, Hyun-Jeong

    2015-01-01

    Several anti-influenza drugs that reduce disease manifestation exist, and although these drugs provide clinical benefits in infected patients, their efficacy is limited by the emergence of drug-resistant influenza viruses. In the current study, we assessed the therapeutic strategy of enhancing the antiviral efficacy of an existing neuraminidase inhibitor, oseltamivir, by coadministering with the leaf extract from Hedera helix L, commonly known as ivy. Ivy extract has anti-inflammatory, antibacterial, antifungal, and antihelminthic properties. In the present study, we investigated its potential antiviral properties against influenza A/PR/8 (PR8) virus in a mouse model with suboptimal oseltamivir that mimics a poor clinical response to antiviral drug treatment. Suboptimal oseltamivir resulted in insufficient protection against PR8 infection. Oral administration of ivy extract with suboptimal oseltamivir increased the antiviral activity of oseltamivir. Ivy extract and its compounds, particularly hedrasaponin F, significantly reduced the cytopathic effect in PR8-infected A549 cells in the presence of oseltamivir. Compared with oseltamivir treatment alone, coadministration of the fraction of ivy extract that contained the highest proportion of hedrasaponin F with oseltamivir decreased pulmonary inflammation in PR8-infected mice. Inflammatory cytokines and chemokines, including tumor necrosis factor-alpha and chemokine (C-C motif) ligand 2, were reduced by treatment with oseltamivir and the fraction of ivy extract. Analysis of inflammatory cell infiltration in the bronchial alveolar of PR8-infected mice revealed that CD11b+Ly6G+ and CD11b+Ly6Cint cells were recruited after virus infection; coadministration of the ivy extract fraction with oseltamivir reduced infiltration of these inflammatory cells. In a model of suboptimal oseltamivir treatment, coadministration of ivy extract fraction that includes hedrasaponin F increased protection against PR8 infection that could be

  20. Folate, vitamin B12, and vitamin B6 status of a group of high socioeconomic status women in the Alberta Pregnancy Outcomes and Nutrition (APrON) cohort.

    PubMed

    Fayyaz, Faiqa; Wang, Flora; Jacobs, René L; O'Connor, Deborah L; Bell, Rhonda C; Field, Catherine J

    2014-12-01

    Folic acid supplementation and food fortification policies have improved folate status in North American women of child bearing age. Recent studies have reported the possible inadequacy of vitamin B12 and B6 in the etiology of neural tube defects in folate-fortified populations. The aims of this study were to describe folate status and its relationship to supplementation and to assess vitamin B12 and B6 status in a cohort of pregnant women. Supplement intake data were collected in each trimester from the first cohort (n = 599) of the Alberta Pregnancy Outcomes and Nutrition (APrON) study. Red blood cell folate (RBCF) and plasma folate, holotranscobalamin, and pyridoxal 5-phosphate were measured. Overt folate deficiency was rare (3%) but 24% of women in their first trimester had suboptimal RBCF concentration (<906 nmol·L(-1)). The proportion of the cohort in this category declined substantially in second (9%) and third (7%) trimesters. High RBCF (>1360 nmol·L(-1)) was observed in approximately half of the women during each pregnancy trimester. Vitamin B12 and B6 deficiencies were rare (<1% of the cohort). Women consuming folic acid supplements above the upper level had significantly higher RBCF and plasma folate concentrations. In conclusion, the prevalence of vitamin B12 and B6 deficiency was very low. A quarter of the women had suboptimal folate status in the first trimester of pregnancy and over half the women had abnormally high RBCF, suggesting that supplementation during pregnancy is not appropriate in a cohort of women considered to be healthy and a low risk for nutritional deficiencies.

  1. Development of a murine nose-only inhalation model of influenza: comparison of disease caused by instilled and inhaled A/PR/8/34

    PubMed Central

    Bowen, Larry E.; Rivers, Katie; Trombley, John E.; Bohannon, J. Kyle; Li, Shixiong X.; Boydston, Jeremy A.; Eichelberger, Maryna C.

    2012-01-01

    Influenza continues to cause widespread disease and death during winter months. In preclinical studies to evaluate the potential efficacy of drugs and vaccines, influenza challenge virus is usually instilled into the noses of animals in the form of large liquid drops. Since inhalation of aerosolized influenza is commonly associated with human transmission, instillation of challenge virus raises uncertainty about the applicability of results. In order to compare the challenge methods, we established conditions to generate influenza aerosols with a mass median aerodynamic diameter (MMAD) of 1 μm that were delivered to mice in a nose-only inhalation system. In this report, we describe the system and compare the 50% lethal dose (LD50) of instilled and inhaled A/PR/8/34 (PR8) in BALB/c mice. The estimated LD50 for inhaled virus was 8.7 plaque forming units (PFU) and the mean time to death was 7.7 days, whereas the estimated LD50 for instilled virus was 51.6 PFU and the mean time to death was 8.2 days. Our results show that mice are more sensitive to inhaled virus than virus delivered by intranasal instillation. The murine nose-only inhalation model of influenza infection can be used to infect large numbers of animals simultaneously with well-characterized, homogenous PR8 bioaerosol in a controlled and reproducible manner. This model provides the means to evaluate the efficacy of drug and vaccine candidates against the relevant route of challenge, thereby providing data that may better predict clinical outcome. PMID:22919665

  2. ECC Water Film Spreading, ECC Water Bypass and Sweep-out Phenomena in the Downcomer with DVI of APR1400 under LBLOCA

    SciTech Connect

    Lee, Dong Won; No, Hee Cheon; Kim, Han Kon; Oh, Seung Jong

    2002-07-01

    In the present study, several experiments related to the thermal-hydraulic phenomena in downcomer with DVI under LBLOCA (Large Break Loss of Coolant Accident) were carried out using the experimental facility of plane-channel type scaled down as 1/7 ratio of prototype reactor (APR1400). Especially, phenomena such as ECC (Emergency Core Cooling) water entrainment and mixing in the downcomer were focused in the present study. Water film spreading was studied and compared with the full-scaled experiment and the experiment with a 1/7 scaled cylindrical-type test section to see the scaling effect and its curvature effect. It turns out that the curvature effect is negligible and the present modified linear scaling law is more appropriate than the linear scaling law. The water height and the amount of ECC water bypass by onset of sweep-out were measured from the visual observation of sweep-out in the downcomer. From this test, the onset of continuous sweep-out was used to analyze the water height in the downcomer. The amount of ECC water bypass by sweep-out was measured and compared with the UCB and KfK correlations. It is found that the best fit of the data from the present experiment lies between the predictions by the two correlations. ECC water mixing phenomena in downcomer were observed focusing on the ECC water film behavior. From the air and water mixing tests, it is concluded that ECC water bypass fraction is highly dependent on DVI position rather than gas flow rates and ECC water bypass fraction is less than 10% of injection ECC water. From the steam and water mixing tests, it is concluded that ECC bypass fraction with steam injection is under 1.5% and much less than that with an air injection because of the condensation in the downcomer. (authors)

  3. Coadministration of Hedera helix L. Extract Enabled Mice to Overcome Insufficient Protection against Influenza A/PR/8 Virus Infection under Suboptimal Treatment with Oseltamivir.

    PubMed

    Hong, Eun-Hye; Song, Jae-Hyoung; Shim, Aeri; Lee, Bo-Ra; Kwon, Bo-Eun; Song, Hyuk-Hwan; Kim, Yeon-Jeong; Chang, Sun-Young; Jeong, Hyeon Gun; Kim, Jong Geal; Seo, Sang-Uk; Kim, HyunPyo; Kwon, YongSoo; Ko, Hyun-Jeong

    2015-01-01

    Several anti-influenza drugs that reduce disease manifestation exist, and although these drugs provide clinical benefits in infected patients, their efficacy is limited by the emergence of drug-resistant influenza viruses. In the current study, we assessed the therapeutic strategy of enhancing the antiviral efficacy of an existing neuraminidase inhibitor, oseltamivir, by coadministering with the leaf extract from Hedera helix L, commonly known as ivy. Ivy extract has anti-inflammatory, antibacterial, antifungal, and antihelminthic properties. In the present study, we investigated its potential antiviral properties against influenza A/PR/8 (PR8) virus in a mouse model with suboptimal oseltamivir that mimics a poor clinical response to antiviral drug treatment. Suboptimal oseltamivir resulted in insufficient protection against PR8 infection. Oral administration of ivy extract with suboptimal oseltamivir increased the antiviral activity of oseltamivir. Ivy extract and its compounds, particularly hedrasaponin F, significantly reduced the cytopathic effect in PR8-infected A549 cells in the presence of oseltamivir. Compared with oseltamivir treatment alone, coadministration of the fraction of ivy extract that contained the highest proportion of hedrasaponin F with oseltamivir decreased pulmonary inflammation in PR8-infected mice. Inflammatory cytokines and chemokines, including tumor necrosis factor-alpha and chemokine (C-C motif) ligand 2, were reduced by treatment with oseltamivir and the fraction of ivy extract. Analysis of inflammatory cell infiltration in the bronchial alveolar of PR8-infected mice revealed that CD11b+Ly6G+ and CD11b+Ly6Cint cells were recruited after virus infection; coadministration of the ivy extract fraction with oseltamivir reduced infiltration of these inflammatory cells. In a model of suboptimal oseltamivir treatment, coadministration of ivy extract fraction that includes hedrasaponin F increased protection against PR8 infection that could be

  4. Première expérience de l'utilisation du Misoprostol comme soin après avortement (SAA) à Libreville, Gabon

    PubMed Central

    Mayi-Tsonga, Sosthène; Minkobame, Ulysse; Mbila, Arielle; Assoumou, Pamphile; Diop, Ayisha; Winikoff, Beverly

    2014-01-01

    Introduction Une étude a été menée afin de déterminer le taux d'acceptabilité de 400µg de misoprostol par voie sublinguale comme traitement de première intention de l'avortement incomplet et de préciser le taux d'avortement complet ou vacuité utérine. Méthodes Les femmes éligibles avaient un diagnostic clinique d'avortement incomplet avec une taille utérine inférieure à celle d'un utérus de 12 semaines d'aménorrhées (SA). Chacune a reçu 400µg de misoprostol par voie sublinguale. Les femmes ont été revues après une semaine. A J7, celles qui n'avaient pas complètement expulsé ont eu le choix entre une nouvelle consultation de suivi à J14 et la pratique d'une évacuation chirurgicale immédiate. Résultats 145 patientes ont été éligibles et ont toutes accepté la méthode (100%). L’âge moyen était de 25,9 ± 6 ans. A J7, 120 patientes étaient guéries (85,7%). A J14, le taux de réussitea été de 95,7% soit 134 patientes guéries. Les patientes guéries ont déclaré être très satisfaites (57,5%), satisfaites (41,8%) et insatisfaite (0,7%). Au total,128 femmes (95,5%) ont dit être prêtes à utiliser de nouveau le misoprostol comme méthode d’évacuation utérine en cas d'avortement incomplet. Conclusion L’étude démontre que le 400µg misoprostol par voie sublinguale nous permet de prendre en charge d'une manière adéquate l'avortement incomplet surtout dans les pays à faible ressource et notamment dans les structures sanitaires de première ligne ou éloignées. PMID:25469194

  5. Associations between the prevalence of influenza vaccination and patient's knowledge about antibiotics: a cross-sectional study in the framework of the APRES-project in Austria.

    PubMed

    Hoffmann, Kathryn; van Bijnen, Evelien Me; George, Aaron; Kutalek, Ruth; Jirovsky, Elena; Wojczewski, Silvia; Maier, Manfred

    2015-09-29

    This study aimed to identify associations between GP patient's knowledge about the spectrum of effectiveness of antibiotics and the probability of vaccination against influenza. The underlying hypothesis was that individuals with an understanding that antibiotics are ineffective against viruses, common colds, and flu were more likely to be vaccinated than persons lacking this knowledge. This cross-sectional study was conducted within the context of the European APRES project in Austria. Between November 2010 and July 2011, patients were recruited from GP practices to complete questionnaires about their knowledge about antibiotics and their influenza vaccination status. Statistical analyses included subgroup analyses and logistic regression models. Data of 3224 patients was analyzed, demonstrating that patients with better knowledge concerning antibiotics had a significantly higher likelihood of being vaccinated (OR 1.35, CI 95 % 1.18-1.54). While the overall vaccination rate was low (18.6 % in 2009/2010 and 14.0 % in 2010/2011), elderly compared to younger adults (OR 0.06 CI 95 % 0.03-0.13) and healthcare workers (OR 2.24, CI 95 % 1.42-3.54) demonstrated higher likelihood of vaccination. Additionally, female GPs had significantly more vaccinated patients than male GPs (OR 2.90, CI 95 % 1.32-6.40). There has been little prior study on the association between a patient's knowledge of the effectiveness spectrum of antibiotics and influenza vaccination status. Given the public health imperative to increase annual prevalence of influenza vaccination, understanding this educational gap can improve specificity in counseling as well as vaccination rates. Ultimately, we found that those with a better knowledge on about antibiotics had a significantly higher likelihood of being vaccinated. The results of this study demonstrate that vaccination prevalence is associated with patient's knowledge about antibiotics. It can be concluded that one strategy to improve the overall low

  6. Calcul par simulation des paramètres dosimétriques pour le noyau cellulaire après irradiation α in vitro

    NASA Astrophysics Data System (ADS)

    Le Foll, L.; Bailly, I.; Fritsch, P.

    1998-04-01

    Determination of absorbed dose in biological targets after high LET α particules irradiation needs heavy calculations. A softwave has been developed in order to allow everyone to calculate hit probability and absorbed dose. It is particularly adapted to the study of cell cultures irradiated with electrodeposited source or α-beam accelerator. It is based first, on a random generator of α-track homogeneously distributed in 4π, second, on the evaluation of energy loss in the different media along the track and then on a statistical analysis of the results. This method is accurate and low time consuming. The target is either modelised by an ellipsoid or represented by its 3D shape recorded using confocal microscopy. Des calculs dosimétriques complexes sont nécessaires pour l'évaluation des doses délivrées dans des cibles biologiques après irradiation par des particules α de haut TEL. Un logiciel a été développé pour rendre facilement accessible le calcul de la probabilité pour atteindre la cible et de la dose absorbée. il est particulièrement adapté à l'étude des cultures cellulaires irradiées par des sources électrodéposées de radionucléides ou des accélérateurs de particules. Il repose sur un générateur de traces aléatoires, sur une approximation de la perte d'énergie dans les différents milieux traversés et sur une exploitation statistique des résultats obtenus. Cette méthode s'avère précise et rapide. La cible est modélisée par un ellipsoïde ou représentée par son image 3D obtenue en microscopie confocale.

  7. Variability of the SPCZ as detected by a statistical model using thirty years of 3-hrly geostationary IR images in Nov-Apr

    NASA Astrophysics Data System (ADS)

    Magnusdottir, G.; Haffke, C. M.

    2014-12-01

    The mean state, interannual variability, seasonal evolution, intraseasonal and diurnal variability of the SPCZ are quantified using a data set of 3-hourly SPCZ labels, available from 1980 to 2012, Nov-Apr. The SPCZ label is a binary field indicating presence or absence of the SPCZ at each horizontal grid point (½º lon by ½º lat) as a function of time and is based on output of a Bayesian spatiotemporal statistical model that takes in instantaneous data from geostationary satellites. The statistical model is specifically designed to emulate the way a human observer identifies the SPCZ. Results show two distinct parts to the SPCZ, the western tropical part and the eastern subtropical part. For certain time periods, the two parts do not connect. They are oriented quite differently, such that the subtropical part has a steeper meridional slope. The SPCZ is present 50-70% of the time in the tropics from Jan-Mar and is usually anchored to the warm SST distribution of the equatorial west Pacific. The subtropical part of the SPCZ does not have the same sensitivity to the underlying SST distribution and is present more often in Nov-Dec and April than in Jan-Mar when the SST is highest. Diurnal variability in cloud top height within the SPCZ also highlights the two distinct parts of the SPCZ. The tropical part has a diurnal cycle of cloudiness typical of that for the boreal summer ITCZ in the east Pacific whereas that is not the case for the subtropical part. Interannual variability in SPCZ location is strongly associated with ENSO, however no change in overall SPCZ area is associated with ENSO. On the intraseasonal timescale, the MJO has a strong and direct signature in SPCZ location. Panels in the figure below show composites of SPCZ labels, in units of fraction of time present, during each season after the seasonal cycle has been removed. Red (blue) shading indicates areas where the SPCZ is more (less) frequently present in each season compared to the mean. Bold black

  8. A study on the effect of various design parameters on the natural circulation flow rate of the ex-vessel core catcher cooling system of EU-APR1400

    SciTech Connect

    Rhee, B. W.; Ha, K. S.; Park, R. J.; Song, J. H.

    2012-07-01

    In this paper, a study on the effect of various design parameters such as the channel gap width, heat flux distribution, down-comer pipe size and two-phase flow slip ratio on the natural circulation flow rate is performed based on a physical model for a natural circulation flow along the flow path of the ex-vessel core catcher cooling system of an EU-APR1400, and these effects on the natural circulation flow rate are analyzed and compared with the minimum flow rate required for the safe operation of the system. (authors)

  9. Amélioration de la calcinose tumorale de la main droite après para thyroïdectomie chez un hémodialysé chronique

    PubMed Central

    El Maghraoui, Jaouad; Hammou, Mohamed; Kabbali, Nadia; Arrayhani, Mohamed; Houssaini, Tariq Sqalli

    2016-01-01

    Les calcifications des tissus péri articulaires sont fréquentes chez les insuffisants rénaux chroniques en hémodialyse. Nous rapportons le cas d'un hémodialysé chronique depuis 10 ans qui a présenté une calcinose pseudo tumorale isolé à la main droite nettement améliorée après para thyroïdectomie. A travers cette observation, nous montrons l'impact du para thyroïdectomie sur la calcinose pseudo tumorale. PMID:27583094

  10. Complications métaboliques après transplantation rénale à partir du donneur vivant: expérience du CHU Ibn Sina de Rabat

    PubMed Central

    Mouram, Hala; Benamar, Loubna; Ouzeddoune, Naima; Bayahia, Rabia; Ezaitouni, Fatima

    2014-01-01

    La transplantation rénale (TR) constitue le traitement de choix de l'insuffisance rénale chronique terminale. Les complications métaboliques après TR (diabète, dyslipidémie, hyperuricémie, obésité), en grande partie liées au traitement immunosuppresseur, deviennent une préoccupation car elles constituent un facteur de risque de morbimortalité et de perte fonctionnelle du greffon. Le but de notre étude est d’évaluer la fréquence de ces anomalies après TR. Il s'agit d'une étude rétrospective incluant tous les patients ayant bénéficié d'une première TR par donneur vivant (DV) de Juin 1998 à Décembre 2010. Nous avons recensé les données démographiques propres au receveur, le traitement immunosuppresseur après TR. Les paramètres clinico-biologiques recueillis sont (index de masse corporel (IMC), glycémie à jeun, hémoglobine glyquée, CT, C-HDL, C-LDL, TG, acide urique). Soixante dix patients ont été colligés, l’âge moyen est de 36.3 + /-9.6 ans (21 à 62) avec un sex ratio de 0.5. Quinze patients (21.4%) étaient hypertendus avant la TR et 2.9% avaient une néphropathie diabétiques. L’âge moyen du donneur est de 47.5 + /-10.2 ans (20-65). Le traitement immunosuppresseur pendant la phase d'induction était une trithérapie associant corticostéroïdes, anticalcineurines chez tous les patients et mycophénolate mofétil chez 68.6% et azathioprine dans 31.4% des cas. L'IMC moyen était de 24.1 + /-4.0 (16.9 à 37), 33% des patients étaient considérés en surpoids dont 21.8% en obésité. L'hypercholestérolémie, a été retrouvée chez 25 patients soit 36%. Presque la moitié des patients (48.5%) avaient une hyperuricémie. Quatre patients ont développé un diabète après TR soit 6% des cas. La perte du greffon a été notée chez 12 patients et 2 patients sont décédés dont un avec un greffon fonctionnel. En analyse univariée, l'hyperuricémie et la dyslipidémie ont été considérées comme facteur de risque de perte

  11. Influence du débit et de la répartition de dose sur l'incidence des cancers pulmonaires après inhalation d'émetteurs

    NASA Astrophysics Data System (ADS)

    Fritsch, P.; Dudoignon, N.; Morlier, J. P.; Monchaux, G.; Morin, M.

    1998-04-01

    We have discussed experimental results reported on the influence of dose rate and dose distribution on the incidence of lung tumors after inhalation exposure to α emitters. New experiments have been carried out to characterize the range of tumor risk which could vary over more than a factor 20 depending on the α activity of the inhaled particles. Long term effects induced in rats after inhalation of poorly soluble 237NpO2 and industrial PuO2 with a similar granulometry will be compared, the specific activities of which varying within a factor 500. Nous avons rapporté les différentes données expérimentales de cancérogenèse pulmonaire qui montrent une variation du risque d'induction des tumeurs après inhalation de radionucléides émetteurs α selon le débit et la répartition de dose. De nouvelles expérimentations ont été initiées afin de préciser ces variations qui s'étalent sur plus d'un facteur 20. Elles consistent à comparer les effets induits chez le rat après exposition à des aérosols de 237NpO2 et de PuO2 d'origine industrielle peu solubles et de granulométrie analogue dont les activités spécifiques diffèrent d'un facteur 500.

  12. Electrical, magnetic and magnetocaloric properties of polycrystalline Pr0.63A0.07Sr0.3MnO3 (A=Pr, Sm and Bi)

    NASA Astrophysics Data System (ADS)

    Elghoul, A.; Krichene, A.; Boujelben, W.

    2016-11-01

    We studied the effects of the partial substitution (10%) of praseodymium by samarium and bismuth, on the structural, magnetic, magnetocaloric and electrical properties of the Pr0.63A0.07Sr0.3MnO3 (A=Pr, Sm and Bi) manganites prepared using the solid state reaction. Refinement of the X-ray diffraction patterns shows that all our samples are single phase and crystallize in the orthorhombic structure with Pnma space group. Magnetic studies indicate that all the samples exhibit a ferromagnetic-paramagnetic transition with increasing temperature. Curie temperature TC decreases by substitution. M(H) curves indicate the presence of some antiferromagnetic domains in the substituted samples testifying the phase-separated nature of these samples. The magnetic entropy curves -ΔS(T) show a maximum in vicinity of TC. Important values of maximum of -ΔS are recorded for our compounds. For the parent compound, we found 4.59 J/kg K for an applied magnetic field of 2 T at TC=266 K which raises the possibility of using this compound as a magnetic refrigerant. The temperature dependence of the electrical resistivity ρ(T) indicates that all compounds exhibit a metal-insulator transition with increasing temperature. Electrical study suggests the presence of a correlation between electrical and magnetic properties.

  13. [Evaluation of the appropriateness of hospital admissions using the iso-gravity classification systems APR-DRG and Disease Staging and the Italian version of Appropriateness Evaluation Protocol (AEP)].

    PubMed

    D'Andrea, G; Capalbo, G; Volpe, M; Marchetti, M; Vicentini, F; Capelli, G; Cambieri, A; Cicchetti, A; Ricciardi, G; Catananti, C

    2006-01-01

    Our main purpose was to evaluate the organizational appropriateness of admissions made in a university hospital, by comparing two iso-gravity classification systems, APR-DRG and Disease Staging, with the Italian version of AEP (PRUO). Our analysis focused on admissions made in 2001, related to specific Diagnosis Related Groups (DRGs), which, according an Italian Law, would be considered at high risk of inappropriateness, if treated as ordinary admissions. The results obtained by using the 2 classification systems did not show statistically significant differences with respect to the total number of admissions. On the other hand, some DRGs showed statistically significant differences due to different algorithms of attribution of the severity levels used by the two systems. For almost all of the DRGs studied, the AEP-based analysis of a sample of medical records showed an higher number of inappropriate admissions in comparison with the number expected by iso-gravity classification methods. The difference is possibly due to the percentage limits of tolerability fixed by the Law for each DRG. Therefore, the authors suggest an integrated use of the two methods to evaluate organizational appropriateness of hospital admissions.

  14. Landau theory and critical behavior near the ferromagnetic-paramagnetic transition temperature in Pr0.63A0.07Sr0.3MnO3 (A=Pr, Sm and Bi) manganites

    NASA Astrophysics Data System (ADS)

    Elghoul, A.; Krichene, A.; Boujelben, W.

    2017-09-01

    In this work, we are interested in the study of the critical behavior and the Landau theory of Pr0.63A0.07Sr0.3MnO3 (A=Pr, Sm and Bi) compounds. The critical exponents of all our samples were studied using the magnetic field dependent isothermal magnetization around Curie temperature TC, based on various techniques. The validity of our critical exponents is confirmed by the scaling analysis. The study revealed that tricritical mean field model is the best for calculating the critical exponents for all our samples. The substitution of praseodymium by samarium and bismuth does not change the universality class. Using Landau theory, we have confirmed that the magnetic transition around TC is of second-order. An agreement was found between the (-ΔS) values estimated by Landau theory and those obtained using Maxwell relation for a magnetic field equal to 2 T, which shows the validity of this theory for all our compounds. The deviation obtained for bismuth and samarium based samples below TC can be attributed to the existence of some antiferromagnetic domains in the ferromagnetic phase.

  15. Structure and magnetic properties of new Be-substituted langasites A{sub 3}Ga{sub 3}Ge{sub 2}BeO{sub 14} (A=Pr, Nd, and Sm)

    SciTech Connect

    Sharma, A.Z.; Silverstein, H.J.; Hallas, A.M.; Luke, G.M.; Wiebe, C.R.

    2016-01-15

    Langasites have been studied extensively in past for their functional properties and use in telecommunication. A thorough understanding of their ground state is limited by the difficulty in synthesizing new members belonging to this series due to the formation of competing phases such as the garnets. Three magnetic langasites A{sub 3}Ga{sub 3}Ge{sub 2}BeO{sub 14} (A=Pr, Nd, and Sm) and a non-magnetic lattice standard La{sub 3}Ga{sub 3}Ge{sub 2}BeO{sub 14} were synthesized using the ceramic method. These were further characterized by X-ray diffraction, magnetization, magnetic susceptibility and heat capacity measurements. All three langasites exhibit net antiferromagnetic interactions at low temperatures and no evidence of long range magnetic ordering was observed down to 0.350 K. - Graphical abstract: Kagome network formed by the magnetic ions in the new Be-langasites. The ground states of three new members were explored using different physical property measurements such as X-ray diffraction, magnetization, magnetic susceptibility and heat capacity (a–d show refinement patterns for the langasites). These can be added to the list of candidate spin liquid materials. - Highlights: • Four new langasites A{sub 3}Ga{sub 3}Ge{sub 2}BeO{sub 14} (A=La, Pr, Nd, and Sm) were synthesized. • These were characterized using physical and magnetic property measurements. • These langasites exhibit net antiferromagnetic interactions at low temperatures. • No evidence of long range magnetic ordering was observed down to 0.350 K. • Can be potential Spin liquid candidates.

  16. Meteorological Techniques (Revision 26 Apr 2006)

    DTIC Science & Technology

    2003-06-13

    vapor pressure mixes with ambient air at some other temperature and vapor pressure. The technique mixes air from these two sources. It is assumed that...possibility for a microburst event can be incorporated into the forecast. 5. Derechos . Derechos are straight-line winds from severe convective storms. There...are two types of derechos . The first are rapidly propagating segments of an extensive squall line associated with a strong, migratory low-pressure

  17. Senior Noncommissioned Officers’ APR Opinion Survey

    DTIC Science & Technology

    1977-02-01

    in any manner licensing the holder or any other person or corporation, or conveying any rights or permission to manufacture, use, or sell any patented...2 Average Rank Order of Rating Factors ............................... 7 3 Kendal Coefficient of Concordance Values for Rank Ordering of Rating...questionnaire was divided into four sections, The first section (Appendix A, Part I) dealt with demographic and personal information such u age, grade, sex

  18. IRIS Bimonthly Public Meeting (Apr 2014)

    EPA Pesticide Factsheets

    EPA hosted a public meeting/webinar to provide an opportunity for the public to give input and participate in an open discussion regarding several IRIS chemical assessments for Diethyl Phthalate (DEP) and Hexabromocyclododecane (HBCD).

  19. Tomographie par coherence optique pour le guidage de chirurgies minimalement invasives du rachis

    NASA Astrophysics Data System (ADS)

    Beaudette, Kathy

    Adolescent idiopathic scoliosis is a complex 3D deformity of the spine which requires surgical intervention in severe cases of the condition. The existing corrective procedure of scoliosis is very invasive; it involves a long incision and a large instrumentation, in addition to the fusion of a section of the spine. To improve postoperative conditions and to preserve patients' spinal flexibility, novel fusionless surgical approaches involving growth modulation are under investigation. With this objective in mind, a multidisciplinary team from École Polytechnique of Montreal and Sainte-Justine University Hospital Research Center is developing a surgical technique based on the insertion of micro-staples between vertebral growth plates and corresponding intervertebral disks. Each micro-staple passively modulates the vertebral growth on the convex side of the scoliotic curvature. This modulation modifies vertebral geometry which, for scoliotic patients, presents a wedging deformity. The modulation induced by these devices could lead to the correction of the curvature of the spine. This innovative procedure would preserve the flexibility of the spine as well as the health of intervertebral disks, in addition to being compatible with minimally invasive approaches. However, to be efficient, the micro-staples must be placed at the junction between the growth plate and the disk with a sub-millimeter precision. An intraoperative guiding system is therefore required to ensure the success of the intervention. Optical coherence tomography (OCT) is a promising candidate for this application. OCT is based on low-coherence interferometry and provides cross-sectional images with a resolution about 10 μm for a depth of 2 to 3 mm. This technique allows for the real-time acquisition of images and is compatible with endoscopy, thereby showing a potential for the intraoperative guidance of minimally invasive surgeries (MIS) of the spine. The main objective of this master's project is therefore to evaluate the possibility of using OCT to localize as well as identify spinal structures (such as growth plates, osseous tissue, intervertebral disks and connective tissue) and to guide the insertion of micro-staples. To attain this objective, an OCT handheld probe was designed and developed according to the surgical constraints of MIS performed by thoracoscopy (through the thorax). This probe has an external diameter of 17 mm and is 30 cm long. Coupled with a fibered interferometer, the axial and lateral resolutions of the probe are of 16 and 27 μm respectively. The OCT probe was used in vivo during an open surgery on a porcine model. Different tissues within the operative window (lung, muscles, osseous tissues and intervertebral disk) were imaged during the procedure. These preliminary in vivo tests demonstrated that the probe is capable of identifying different types of tissue with a good sensitivity and an adequate penetration depth. These results also showed that a visual inspection of the in vivo OCT images alone is not sufficient to localize the growth plates on the vertebrae. An ex vivo study using porcine vertebrae was therefore performed to identify quantitative markers in order to facilitate the interpretation of in vivo OCT images. OCT images were initially compared to corresponding histological sections. The ensuing results showed that the connective tissue layer presents a band pattern due to the birefringence properties of the collagen-rich tissue. The intervertebral disk was also shown to have a characteristic lamellar structure on OCT images. Lastly, within growth plate and osseous tissue locations, the OCT signal decay is monotonic, but with different attenuation coefficients (different slopes). Relative attenuation coefficients were therefore measured for each tissue (growth plate, osseous tissue, connective tissue and intervertebral disk) on several specimens and were compared. These results showed that growth plates present an average relative attenuation coefficient statistically different from the other tissues. An automatic growth plate segmentation algorithm was then developed and tested. The algorithm was applied to images from an ex vivo specimen of a porcine vertebra and successfully identified most of the growth plate (> 75%) amidst the osseous tissue of the vertebral body and the intervertebral disk. This master's project shows that OCT presents contrast, resolution and penetration depth that are sufficient for the identification of musculoskeletal structures of the spine. It is thus reasonable to believe that, ultimately, OCT could be used for the intraoperative guiding of the insertion of micro-staples during corrective surgeries of scoliosis.

  20. Application de la méthode de Laue refocalisée à haute énergie à l'étude des mécanismes de recristallisation après déformation à froid de métaux CFC

    NASA Astrophysics Data System (ADS)

    Chauveau, Th.; Gerber, Ph.; Bastie, P.; Hamelin, B.; Tarasiuk, J.; Bacroix, B.

    2002-07-01

    In order to determine the kinetics of recystallization process, the Laue diffraction method is apllied here on cold rolled and recrystallized copper materials. Firts, the results obtained from reflexion X-ray diffraction texture measurements are presented. It is shown that the both techniques are complementar, and that the transmission Laue method presents some advantadges. Some previous hypotheses are verified in this work. Especially, the Cube orientation \\{100\\} <001> loses during recrystallization its advantadge of growth, which implies the development of a mixed “deformed-recrystallized” texture at the end of the process. The nucleation step determines the final recrystallized texture. La méthode de Laue haute énergie est appliquée ici dans le but de déterminer les cinétiques de recristallisation de matériaux cuivre après laminages à froid et recuits interrompus. Après présentation des résultats obtenus par mesures classiques en réflexion, une comparaison est effectuée entre les deux techniques permettant de rendre compte des avantages certains qu'offrent des mesures en transmission et de la complémentarité des deux techniques utilisées. Quelques hypothèses sur les mécanismes régissant le processus de recristallisation sont ainsi vérifiées. Au tout début du processus de recristallisation, il a clairement été mis en évidence une perte de l'avantage de croissance des germes d'orientation Cube \\{100\\} <001> au profit des composantes constituant la texture de déformation. Dans ce type de processus, n'est préférentielle que l'étape de germination, dans le sens où elle détermine la texture finale après recristallisation.

  1. Analyse par diffraction des neutrons des déformations résiduelles dans un alliage de zirconium après un chargement thermomécanique

    NASA Astrophysics Data System (ADS)

    Letouzé, N.; Brenner, R.; Béchade, J. L.; Castelnau, O.; Mathon, M. H.; Bacroix, B.

    2002-07-01

    After a thermomechanical loading, it resides within a polycrystalline material an heterogeneous elastic strain field resulting from accommodation of the plastic and/or thermal local deformations. X-rays or neutrons diffraction makes it possible to quantify the average strain and their fluctuations within the diffracting volume (displacement and broadening of the line profil). When measurements are taken in volume (neutrons in our case) on a massive sample containing a large number of grains, they can be compared precisely with the results of homogenisation methods. Indeed, they are, as well as diffraction, a statistical method to analysis local mechanical fields. Moreover, they give access not only to the average mechanical fields by family of orientation (first order moment), but also to the heterogeneity of these fields (second order moment) on the same family and thus by extension on a diffracting volume. We have the results obtained on Zircaloy-4 having undergone a creep in traction at 400^{circ}C, which validates the methodology of comparison between measurements and the simulation carried out with a model of nonlinear homogenisation (self-coherent type affine in thermoelastoviscoplasticity) via the “residual strain map”. Après un chargement thermomécanique, il réside au sein d'un matériau polycristallin un champ de déformation élastique hétérogène issu de l'accommodation des déformations locales plastiques et/ou thermiques. La diffraction des rayons X ou des neutrons permet de quantifier les déformations moyennes et leurs fluctuations au sein du volume diffractant (déplacement et élargissement de la raie de diffraction). Lorsque les mesures sont effectuées en volume (neutrons dans notre cas) sur un échantillon massif contenant un grand nombre de grains, elles peuvent être comparées précisément aux résultats des méthodes d'homogénéisation. En effet, ils sont, au même titre que la diffraction, une méthode statistique d'analyse des

  2. General geology, geophysics, and seismicity of northwest Alabama. Technical report Apr 79-Apr 80

    SciTech Connect

    Kidd, J.T.

    1980-06-01

    The Geological survey of Alabama and the U.S. Nuclear Regulatory Commission are making a study of the general geology, geophysics, and seismicity of that area in northwest Alabama that is located within a 200-mile radius of New Madrid, Missouri. Rocks exposed in the study area and penetrated in the subsurface range in age from Cambrian to Holocene. Numerous faults and folds have been reported in rocks as old as possible Precambrian and as young as possibly the Cretaceous. Geophysical surveys in the study area show several anomalies. Of particular interest is the apparent shared location between a large gravity anomaly and a low geothermal gradient anomaly. Seismic data indicate the area is in a zone of negligible to moderate seismic risk but two earthquakes have been reported. Maximum earthquake intensities recorded for the study area based on all historical earthquakes affecting Alabama between 1811-1977 range from 4 to 7 (Modified Mercalli).

  3. Protocols for evaluating oxidant mechanisms for urban and regional models. Rept. for Apr 89-Apr 92

    SciTech Connect

    Jeffries, H.E.; Gery, M.W.; Carter, W.P.L.

    1992-06-01

    Procedures have been developed for evaluating chemical kinetics mechanisms that are candidates for use in urban and regional air quality simulation models. To accomplish the goal, a task force of experimentalists and modelers was assembled to address issues related to developing protocols for evaluating mechanisms against smog chamber data. The efforts of the task force were scrutinized in two workshops attended by national and international experts on smog chamber experimentation and model development. Based on the work undertaken by the task force and the input received from the committee of experts, a protocol was formulated that involves testing mechanisms against a standard data base of smog chamber experiments. The protocol describes the types and number of chamber experiments that should be used in the evaluation and how the evaluation should be conducted.

  4. Surface-Based Observations of Contrail Occurrence Over the US, Apr. 1993 to Apr. 1994

    NASA Technical Reports Server (NTRS)

    Minnis, Patrick; Ayers, J. Kirk; Weaver, Steven P.

    1997-01-01

    Surface observers stationed at 19 U.S. Air Force Bases and Army Air Stations recorded the daytime occurrence of contrails and cloud fraction on an hourly basis for the period April 1993 through April 1994. Each observation uses one of four main categories to report contrails as unobserved, non-persistent, persistent, and indeterminate. Additional classification includes the co-occurrence of cirrus with each report. The data cover much of the continental U.S. including locations near major commercial air routes. The mean annual frequency of occurrence in unobstructed viewing conditions is 13 percent for these sites. Contrail occurrence varied substantially with location and season. Most contrails occurred during the winter months and least during the summer with a pronounced minimum during July. Although nocturnal observations are not available, it appears that the contrails have a diurnal variation that peaks during mid morning over most areas. Contrails were most often observed in areas near major commercial air corridors and least often over areas far removed from the heaviest air traffic. A significant correlation exists between mean contrail frequency and aircraft fuel usage above 7 km suggesting predictive potential for assessing future contrail effects on climate.

  5. Lymphangiome kystique cervico-thoracique: à propos d’un cas

    PubMed Central

    Nadour, Karim; Moujahid, Mountassir

    2016-01-01

    Les lymphangiomes kystiques cervico-thoraciques sont des tumeurs bénignes rares, ils proviendraient d'une séquestration du sac lymphatique embryonnaire qui se remplirait progressivement de liquide lymphatique. Le diagnostic est évoqué par la clinique (tuméfaction latéro-cervicale) et l'imagerie (échographie et tomodensitométrie), puis confirmé par l'histologie après la chirurgie qui constitue la base du traitement. Nous rapportons un cas de lymphangiome kystique cervico-thoracique avec une revue de la littérature. PMID:28292151

  6. [What is the benefit of salt reduction on blood pressure? Assessment of the Cochrane Review: Effect of longer-term modest salt reduction on blood pressure. He FJ, Li J, Macgregor GA. Cochrane Database Syst Rev. 2013 Apr 30;4:CD004937].

    PubMed

    Caldeira, Daniel; Vaz-Carneiro, António; Costa, João

    2013-01-01

    No presente artigo avaliamos e comentamos a Revisão Sistemática da Cochrane “Effect of longer-term modest salt reduction on blood pressure. Cochrane Database Syst Rev. 2013 Apr 30;4:CD004937”.Questão Clinica: Qual o impacto a longo prazo (≥ 4 semanas) da restrição moderada de ingestão de sal na pressão arterial.Conclusões: Esta revisão sistemática concluiu que a restrição moderada de ingestão de sal (redução média -4,4 g por dia) diminuide forma significativa a pressão arterial (PA) em indivíduos normotensos (-2,42 mmHg PA sistólica; -1,00 mmHg PA diastólica) ou com hipertensão arterial (-5,39 mmHg PA sistólica; -2,82 mmHg PA diastólica). Verificaram-se ligeiros aumentos da actividade da renina plasmática, aldosterona e norepinefrina. Contudo, não se identificaram alterações significativas do perfil lipídico.

  7. Complications inattendues de la chirurgie: deux cas de brûlure par plaque de bistouri électrique

    PubMed Central

    Diop, B.; Sy, A.; Ba, P.A.; MBaye, B.; Wane, Y.; Sarre, S.M.

    2016-01-01

    Summary Les risques d’accidents électriques sont une réalité dans les blocs opératoires avec le nombre croissant d’équipements électriques, électroniques et de liquides inflammables utilisés. Le bistouri électrique demeure le dispositif le plus utilisé pour son effet électrochirurgical de coagulation ou section tissulaire. Lorsque qu’elle est défectueuse ou mal placée sur une surface réduite de la peau, la plaque du bistouri peut être à l’origine de brûlure cutanée classiquement profonde, de cicatrisation lente. Elle ajoute à l’affection initiale une surmorbidité iatrogène, inattendue, aux conséquences dévastatrices pour le patient, le chirurgien et parfois la structure hospitalière. Nous rapportons deux cas de brûlure cutanée par plaque de bistouri survenue en peropératoire lors de l’utilisation du bistouri électrique en mode monopolaire et discutons les aspects étiologiques, cliniques et préventifs. PMID:28289364

  8. Semiannual Report: Apr 1, 2010 - Sept 30, 2010

    EPA Pesticide Factsheets

    Semiannual Report #EPA-350-R-10-005, Nov, 2010. The OIG will do its best to help the Agency address the nation’s critical environmental challenges by ensuring that Agency funds are properly expended to safeguard human health and the environment.

  9. Semiannual Report: Apr 1, 2003 - Sept 30, 2003

    EPA Pesticide Factsheets

    Semiannual Report #EPA-350-K-03-002, Nov, 2003. We recently issued a major report examining how EPA responded to the crisis at the World Trade Center following the terrorist attacks on September 11, 2001.

  10. WFC3/UVIS EPER CTE Cycles Aug 2009 - Apr 2016

    NASA Astrophysics Data System (ADS)

    Khandrika, H.; Baggett, S.; Bowers, A.

    2016-05-01

    This report summarizes the changes in Charge Transfer Efficiency (CTE) as determined by the Extended Pixel Edge Response (EPER) method. The results are derived from data acquired during Cycle 17 through Cycle 22 (August 2009-present). The EPER method uses large overscan regions obtained via a non-standard readout mode to measure CTE trails as a function of distance from the last row of illuminated science pixels. The CTE decline is steepest at the lowest signal values (160 e- signal level) and more shallow at the highest signal levels (5000 e-). We measure the evolution of CTE since the installation of WFC3; over 7 years the CTE has degraded by 0.07% for the lowest illumination level.

  11. Asteroid Lightcurve Analysis at the Danhenge Observatory Apr - Aug 2011

    NASA Astrophysics Data System (ADS)

    Coley, Daniel

    2012-01-01

    The lightcurves for three main-belt asteroids, 1413 Roucarie, 3385 Bronnina, and 39890 Bobstephens. All observations were taken from the DanHenge Observatory, one of 13 observatories at Goat Mountain Astronomical Research Station (GMARS - MPC G79).

  12. WFC3/UVIS Read Noise Aug 2009 - Apr 2017

    NASA Astrophysics Data System (ADS)

    Khandrika, H.

    2017-06-01

    This report updates the study of the WFC3/UVIS read noise using data taken over a period from August 2009 to June of 2017. The read noise was measured using full-frame UVIS bias images and computed over the main CCD image area. Overall the read noise has increased by 0.06 to 0.075 e- (a 2%-2.6% increase since 2010 - 0.01 electrons per year) and the trends remain linear with no deviations or sudden changes. The increases in read noise are an indirect measure of the CTE degradation as well as the growth in the number of hot pixels.

  13. Semiannual Report: Apr 1, 2011 - Sept 30, 2011

    EPA Pesticide Factsheets

    Semiannual Report #EPA-350-R-11-036, Nov, 2011. We have made great progress and I look forward to fulfilling the new Office of Inspector General vision of being the best in public service and oversight for a better environment tomorrow.

  14. Semiannual Report: Apr 1, 2009 - Sept 30, 2009

    EPA Pesticide Factsheets

    Semiannual Report #EPA-350-R-09-036, Nov, 2009. The OIG took numerous steps during the past semiannual reporting period to help the EPA properly and efficiently spend the $7.2 billion it has received under the American Recovery & Reinvestment Act of 2009.

  15. Semiannual Report: Apr 1, 2012 - Sept 30, 2012

    EPA Pesticide Factsheets

    Semiannual Report #EPA‐350‐R‐12‐003, Nov, 2012. Our work will continue to add value and assist the Agency in accomplishing its mission of safeguarding the health of the American people and protecting the environment.

  16. CSB Semiannual Report: Apr 1, 2012 - Sept 30, 2012

    EPA Pesticide Factsheets

    Nov 2012. This CSB Semiannual Report contains the results of our work related to the U.S. Chemical Safety and Hazard Investigation Board (CSB) for the reporting period April 1, 2012, through Sept 30, 2012.

  17. Semiannual Report: Apr 1, 2007 - Sept 30, 2007

    EPA Pesticide Factsheets

    Semiannual Report #EPA-350-R-07-003, Nov, 2007. This semiannual report includes details on these and other issues, including investigations that resulted in payments to the Federal Government and criminal, civil, or administrative actions.

  18. Semiannual Report: Apr 1, 2005 - Sept 30, 2005

    EPA Pesticide Factsheets

    Semiannual Report #EPA-350-R-05-003, Dec, 2005. We look forward to the challenges ahead as EPA and the Nation continue the effort to rebuild the Gulf States region and to safeguard our environment for us and for the generations that follow.

  19. Compendium of Unimplemented Recommendations: Apr 1, 2010 - Sept 30, 2010

    EPA Pesticide Factsheets

    Compendium #11-N-0006, Oct 26, 2010. This Compendium, issued in conjunction with the Semiannual Report to Congress and as a separate document to EPA leadership, is part of the OIG’s followup strategy to promote robust internal controls.

  20. FORMAL REPORT NO. 1, 1 APR-30 SEP 65.

    DTIC Science & Technology

    PROTON BEAMS), (*RADIATION EFFECTS, RADIOBIOLOGY, PRIMATES, MICE , EYE, BRAIN, WHOLE BODY IRRADIATION, RADIATION DOSAGE, DOSIMETERS, ROTATION, EXPOSURE(PHYSIOLOGY), TEST EQUIPMENT, INSTRUMENTATION, CYCLOTRONS.

  1. LANDSAT 2 world standard catalog, 1 Jan. - 30 Apr. 1978

    NASA Technical Reports Server (NTRS)

    1978-01-01

    The World Standard Catalog lists imagery acquired by LANDSAT 2 which has been processed and input to the data files during the referenced months. Data, such as cloud cover and image quality, are given for each scene. The microfilm roll and frame on which the scene may be found is also given.

  2. Semiannual Report: Apr 1, 1998 - Sept 30, 1998

    EPA Pesticide Factsheets

    Semiannual Report #EPA-350-R-98-004, Nov, 1998. We look forward to working with the Administrator, Agency managers, Congress, and EPA's various stakeholders to help ensure that EPA delivers the maximum in environmental and health benefits to the public.

  3. Semiannual Report: Apr 1, 2006 - Sept 30, 2006

    EPA Pesticide Factsheets

    Semiannual Report #EPA-350-R-06-005, Oct, 2006. This semiannual report includes details on these and other issues, including a number of investigations that resulted in payments to the Federal government and criminal, civil, or administrative actions.

  4. Introduction: neuropsychological assessment après Luria.

    PubMed

    Tupper, D E

    1999-06-01

    Neuropsychological assessment since Alexander R. Luria's death in 1977 has demonstrated increased sophistication and advancement, and a number of models or approaches to neuropsychological assessment are available worldwide today. This article reviews, in the context of this special issue, Luria's influence on the further development of neuropsychological assessment approaches and methods. Contemporary approaches are summarized and contrasted, and a discussion of neo-Lurian adaptations and extensions of his neuropsychological model is presented. Brief comments about the succeeding articles in this issue help to demonstrate the wide influence sustained by Luria's ideas in various regions of the world.

  5. Exercise Limitation Imposed by an Approved Air Purifying Respirator (APR)

    DTIC Science & Technology

    2010-05-01

    mentioned that they did not have enough time to inhale, that inspiratory muscles were fatigued, that they got out of rhythm with their breathing and...frequency, tidal volume, respiratory duty cycle, mask pressure, resistive effort (WOB/VT), minute ventilation (VE), peak inspiratory flow (Vi peak), rate...and VO2 at end running endurance decreased 15 to 18%. Because required inspiratory pressures from laminar and turbulent flow were so high at the

  6. 2nd Generation Airborne Precipitation Radar (APR-2)

    NASA Technical Reports Server (NTRS)

    Durden, S.; Tanelli, S.; Haddad, Z.; Im, E.

    2012-01-01

    Dual-frequency operation with Ku-band (13.4 GHz) and Ka-band (35.6 GHz). Geometry and frequencies chosen to simulate GPM radar. Measures reflectivity at co- and cross-polarizations, and Doppler. Range resolution is approx. 60 m. Horizontal resolution at surface is approx. 1 km. Reflectivity calibration is within 1.5 dB, based on 10 deg sigmaO at Ku-band and Mie scattering calculations in light rain at Ka-band. LDR measurements are OK to near -20 dB; LDR lower than this is likely contaminated by system cross-polarization isolation. Velocity is motion-corrected total Doppler, including particle fall speed. Aliasing can be seen in some places; can usually be dealiased with an algorithm. .

  7. 15 CFR 740.16 - Additional permissive reexports (APR).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Supplement No. 1 to part 740), other than North Korea and the commodity being reexported is controlled for... Africa, South Korea, Spain, Sweden, Switzerland, Turkey, and the United Kingdom if: (i) Such cameras are...

  8. 15 CFR 740.16 - Additional permissive reexports (APR).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... North Korea and the commodity being reexported is controlled for national security reasons. (b..., South Korea, Spain, Sweden, Switzerland, Turkey, and the United Kingdom if: (i) Such cameras are fully...

  9. 15 CFR 740.16 - Additional permissive reexports (APR).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... North Korea and the commodity being reexported is controlled for national security reasons. (b..., South Korea, Spain, Sweden, Switzerland, Turkey, and the United Kingdom if: (i) Such cameras are fully...

  10. 15 CFR 740.16 - Additional permissive reexports (APR).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Supplement No. 1 to part 740), other than North Korea and the commodity being reexported is controlled for... Africa, South Korea, Spain, Sweden, Switzerland, Turkey, and the United Kingdom if: (i) Such cameras are...

  11. 15 CFR 740.16 - Additional permissive reexports (APR).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... supplement No. 1 to part 740), other than North Korea and the commodity being reexported is controlled for... Africa, South Korea, Spain, Sweden, Switzerland, Turkey, and the United Kingdom if: (i) Such cameras are...

  12. Compendium of Unimplemented Recommendations: Apr 1, 2014 - Sept 30, 2014

    EPA Pesticide Factsheets

    Compendium #15-N-0008, Oct 31, 2014. The OIG identified the unimplemented recommendations based on their significance, material impact, and status in the EPA’s Management Audit Tracking System, as well as through OIG review.

  13. Data report for the Northeast Residential Experiment Station, Apr. 1982

    NASA Astrophysics Data System (ADS)

    Russell, M. C.; Raghuraman, P.; Mahoney, P. C.

    1982-06-01

    Physical performance data obtained from photovoltaic energy systems under test at the Northeast Residential Experiment Station (NE RES) in Concord, Massachusetts, are tabulated for the month of April 1982. Five prototype residential photovoltaic systems are under test at the NE RES, each consisting of a roof mounted array sized to meet at least 50% of the annual electrical demand of an energy conserving house, and an enclosed structure to house the remainder of the photovoltaic system equipment, test instrumentation, and work space. Each system is grid connected. In addition, one full sized PV residence, the Carlisle House, is also being monitored in Carlisle, Massachusetts. The features of the systems and of the houses, are briefly summarized, and the monthly performance of the monitored houses, PV systems, and meteorological data is tabulated. Also tabulated is hourly information for an average day of the month including data on the monitored houses and prototype systems data. Data include energy consumption, array and inverter outputs, energy supplied to and by the utility, solar array panel temperatures, and total tilt insolation. Also included are tables that present the hypothetical energy exchange between the system and the utility if each prototype system supplied energy to each monitored house. These data are also graphed, as well as the duration of time for which the load had a specific value.

  14. Compendium of Unimplemented Recommendations: Apr 1, 2013 - Sept 30, 2013

    EPA Pesticide Factsheets

    Compendium #14-N-0016, Nov 15, 2013. The OIG identified the unimplemented recommendations listed in this Compendium based on their significance, material impact, and status in the EPA’s Management Audit Tracking System.

  15. Semiannual Report: Apr 1, 2015 - Sept 30, 2015

    EPA Pesticide Factsheets

    Semiannual Report #EPA-350-R-15-002, Nov, 2015. During this period, witnesses from the EPA OIG testified at congressional hearings, and the OIG produced reports in response to congressional requests, demonstrating their continued interest in our work.

  16. 2nd Generation Airborne Precipitation Radar (APR-2)

    NASA Technical Reports Server (NTRS)

    Durden, S.; Tanelli, S.; Haddad, Z.; Im, E.

    2012-01-01

    Dual-frequency operation with Ku-band (13.4 GHz) and Ka-band (35.6 GHz). Geometry and frequencies chosen to simulate GPM radar. Measures reflectivity at co- and cross-polarizations, and Doppler. Range resolution is approx. 60 m. Horizontal resolution at surface is approx. 1 km. Reflectivity calibration is within 1.5 dB, based on 10 deg sigmaO at Ku-band and Mie scattering calculations in light rain at Ka-band. LDR measurements are OK to near -20 dB; LDR lower than this is likely contaminated by system cross-polarization isolation. Velocity is motion-corrected total Doppler, including particle fall speed. Aliasing can be seen in some places; can usually be dealiased with an algorithm. .

  17. Tumeur à cellules de Sertoli-Leydig de l’ovaire: à propos d’un cas chez une jeune fille de 22 ans

    PubMed Central

    Moussa, Diallo; Aziz, Diouf Abdoul; Niassy, Diallo Astou Coly; Espérence, Koulimaya Cyre; Youssou, Niang; Charles, Moreau Jean; Alassane, Diouf

    2016-01-01

    Les tumeurs à cellules de Sertoli et Leydig sont des tumeurs sécrétantes rares du mésenchyme et des cordons sexuels. Cependant elles constituent l’une des tumeurs le souvent responsables de syndrome de virilisation. La certitude diagnostique est histologique après la chirurgie et il n’ y'a pas de signe échographie spécifique malgré la forte présomption clinique. Le pronostic comme la plupart des néoplasies est lié au degré de différenciation cellulaire et la présence d’éléments hétérologue en leur sein. L’objectif de notre travail était de rapporter un authentique syndrome de virilisation chez une jeune fille de 22 ans secondaire à une tumeur non épithéliale de l’ovaire à cellule de Sertoli et à cellule de Leydig. Les formes peu différenciées des tumeurs de Sertoli-Leydig ont un potentiel de malignité non négligeable. Le traitement est chirurgical, la chimiothérapie par association de sels de platine et de taxanes constitue un adjuvant intéressant. Le pronostic après la chirurgie est dominé par des récidives. PMID:28154727

  18. Reduction of hexachloroethane and carbon tetrachloride at surfaces of biotite, vermiculite, pyrite, and marcasite. Book chapter Apr 88-Apr 90

    SciTech Connect

    Kriegman-King, M.R.; Reinhard, M.

    1991-01-01

    Contamination of groundwater resources by halogenated compounds spurred the formation of a national program to clean up hazardous waste sites across the United States. Compounds such as carbon tetrachloride (CTET), chloroform (CF), and hexachloroethane (HCA) are a few of the chemicals which have been proposed to be 'characteristic' hazardous wastes to be included in the toxic contaminant leachate potential (TCLP) test. Consequently, chemical and biological transformation pathways are being studied to aid in understanding the fate of these contaminants in groundwater environments and to apply the processes occurring naturally in groundwater environments to remediation technologies. Environmental factors significantly affect the transformation rates and the pathways of halogenated aliphatic compounds. The authors have studied the transformation of tetrachloromethane (CTET), and hexachloroethane (HCA) in homogenous and heterogenous systems designed to simulate groundwater and sediment conditions. The laboratory studies were aimed at (1) identifying the sediment components which may act as reducing components and (2) quantifying the environmental factors which govern the transformation rates. Both model and natural systems were studied. Their data indicate that the humic acid fraction in combination with sulfide and Fe(2+) may promote transformation rates. Similarly, surfaces of sheet silicates, such as biotite and vermiculite, were found to promote degradation of CTET and perchloroethylene, respectively.

  19. Probability of people survival in a nuclear weapon blast environment. Final report 17 Apr 79-24 Apr 80

    SciTech Connect

    Longinow, A.

    1980-05-01

    This study was concerned with predicting the probability of survival of people located in personnel shelters when subjected to the blast effects produced by the detonation of a 1-MT weapon near the ground surface. Personnel shelters analyzed re buried or with the roof slab at grade. The roof slab is the weakest structural component. Its partial or total collapse results in casualties. When the shelter is thus breached, casualties can also be produced by the blast loading when overpressures are sufficiently high. The analysis formulated predicts the probability of roof slab survival when subjected to an airblast loading. Probability of people survival against slab collapse is estimated based on the fraction of shelter area unaffected by collapse. Probability of survival against blast pressure entering the shelter area is determined using available casualty data. Results are combined to yield the probability of survival against both effects. The analysis considers the variability of selected geometric parameters of the roof slab, material properties and airblast parameters.

  20. Etude de la microstructure d'un acier 316 titane apres vieillissement et apres irradiation aux neutrons

    NASA Astrophysics Data System (ADS)

    Brun, G.; Le Naour, J.; Vouillon, M.

    1981-10-01

    La précipitation qui se produit lors de vieillissements de longue durée entre 450 et 700°C dans un acier 316 Ti soit hypertrempé soit écroui, a été étudiée en couplant les techniques de microscopic électronique et de microanalyse X. Pour les cas expérimentaux étudiés, les résultats obtenus montrent que la composition des carbures M 23C 6 et des phases σ, Laves et χ est peu sensible aux conditions de vieillissement et dépend également peu de l'état structural initial. Leur teneur en éléments principaux de l'alliage est d'ailleurs voisine de celle des phases précipitées dans l'acier non stabilisé. Excepté les carbures de type M 6C, toutes ces phases ont une teneur en nickel inférieure à celle de la matrice. Les premiers rérultats obtenus sur des matériaux irradiés aux neutrons montrent que la précipitation sous flux est différente de celle qui se produit dans l'acier vieilli. Les phases γ' et G ainsi que les carbures riches en nickel ont été observés. L'attention a été attirée sur le fait qu'il n'y a pas de corrélation simple entre la vitesse de gonflement et la teneuer résiduelle en nickel de la matrice.

  1. Trace and potentially toxic elements associated with uranium deposits in South Texas. Final report Apr 77-Apr 79

    SciTech Connect

    Henry, C.D.; Kapadia, R.R.

    1983-01-01

    The environmentally sensitive trace elements molybdenum, arsenic, and selenium are concentrated with uranium in ore deposits in South Texas. Cattle grazing in some pastures in mining areas have contracted molybdenosis, a cattle disease resulting from an imbalance of molybdenum and copper. To determine natural concentrations of the elements in soils in the South Texas area and to evaluate possible effects of mining on adjacent agricultural land, two sets of soil samples were collected and analyzed for molybdenum, arsenic, selenium, and copper. Results of the random sampling show that the different geologic formations have different characteristic trace element concentrations. Comparison of molybdenum and copper concentrations in soils and grasses and theoretical considerations of the availability to plants of molybdenum and copper in soils suggest that forage in much of the area studied could have anomalously low copper/molybdenum ratios--low enough to induce molybdenosis in cattle.

  2. Cancers du sein bilatéraux synchrones et grossesse a l'institut Joliot Curie de Dakar (Sénégal)

    PubMed Central

    Zongo, Nayi; Sawadogo, Yobi Alexis; Some, Some Ollo Roland; Bagre, Sidpawalmdé Carine; Ka, Sidy; Diouf, Doudou; Dieng, Mamadou Moustapha; Gaye, Papa Macoumba; Dem, Ahmadou

    2016-01-01

    Décrire notre stratégie diagnostique et thérapeutique dans les cancers du sein bilatéraux synchrones pendant la grossesse. L’âge gestationnel au moment du diagnostic du cancer était respectivement de 7; 21 et 25 semaines. Il s'agissait de stade IV et IIIA respectivement dans deux et un cas. Elles ont toutes bénéficié d'une chimiothérapie dans deux cas pendant la grossesse (6TEC et 3AC) et dans un cas après l'accouchement. Une mastectomie bilatérale a été réalisée dans un cas. Une patiente est décédée. Les autres étaient vivantes mais toutes métastatiques. Une hypotrophie fœtale a été notée dans un cas. Le diagnostic du cancer est tardif dans cette association. La chirurgie est faisable et le type de chirurgie serait seulement fonction du stade du cancer. La chimiothérapie est possible avec moins de complications fœtales aux deux derniers trimestres. PMID:27279967

  3. Bases anatomiques des lésions de l’artère pudendale externe lors de la chirurgie des varices du membre pelvien

    PubMed Central

    Gaye, Magaye; Ndiaye, Assane; Dieng, Papa Adama; Ndiaye, Aynina; Ba, Papa Salmane; Diatta, Souleymane; Ciss, Amadou Gabriel; Ndoye, Jean Marc Ndiaga; Diop, Mamadou; Ndiaye, Abdoulaye; Ndiaye, Mouhamadou; Dia, Abdarahmane

    2016-01-01

    Introduction L’artère pudendale externe est une branche collatérale de l’artère fémorale commune qui est destinée à la vascularisation du pénis ou du clitoris. Ses rapports avec la crosse de la grande veine saphène et de ses afférences, dans le trigone fémoral, sont très étroits. Cette situation fait qu’elle est souvent lésée lors de la crossectomie et de l’éveinage de la grande veine saphène. Ces lésions peuvent être à l’origine d’une dysfonction sexuelle. Méthodes Il s’agit d’une dissection de 22 régions inguinales chez 13 hommes et 9 femmes qui ont bénéficié d’un abord chirurgical du trigone fémoral. La distribution et les rapports de l’artère pudendale externe par rapport à la crosse de la grande veine saphène sont étudiés. Résultats L’artère pudendale externe unique est la plus fréquente. Toutes les artères pudendales externes ont pour origine l’artère fémorale commune. Le rapport le plus fréquent est le sous croisement de la crosse de la grande veine saphène par une artère pudendale externe unique. Par ailleurs, on a un précroisement, un croisement alterné et des rapports avec la veine fémorale commune et des afférences de la crosse de la grande veine saphène. Certaines techniques chirurgicales exposent plus ou moins à une lésion de l’artère pudendale externe. Conclusion Ce travail confirme les données antérieures mais montre encore quelques particularités sur les rapports entre la crosse de la grande veine saphène et l’artère pudendale externe. PMID:27795794

  4. Refractive Surgery: New Techniques and Usability for Military Personnel (La chirurgie refractive: Nouvelles techniques et leur application pour le personnel militaire)

    DTIC Science & Technology

    2012-11-01

    targeted, even in the absence of cataract formation, to correct refractive error. The risk profile of intraocular procedures is different than corneal...change the refractive power. If the natural lens is not opaque with cataract , this procedure is termed ‘clear lens extraction’. Generally, such...cystoid macular edema. The long-term risk of cataract progression and corneal decompensation (loss of the cornea’s ability to regulate its own water

  5. Laparoscopic antireflux surgery: comparative study of Nissen, Nissen-Rossetti, and Toupet fundoplication. Société Française de Chirurgie Laparoscopique.

    PubMed

    Pessaux, P; Arnaud, J P; Ghavami, B; Flament, J B; Trebuchet, G; Meyer, C; Huten, N; Champault, G

    2000-11-01

    The aim of this retrospective study was to compare the results of Nissen, Nissen-Rossetti, and Toupet laparoscopic fundoplication in terms of gastroesophageal reflux disease (GERD). From 1992 to 1996, 1,470 laparoscopic fundoplications were performed using one of three procedures: Nissen (n = 655), Nissen-Rossetti (n = 423), and Toupet (n = 392). Preoperative checkup included esophagogastroduodenoscopy in 1,437 patients (97. 7%), esophageal manometry in 934 patients (63.5%), and 24-h pH-metry in 799 patients (54.3%). The results were estimated at 1 month, 3 months, and 2 years. Patients unable to visit the hospital center were contacted by telephone. The three groups were quite similar regarding demographic data such as age, gender, preoperative clinical symptoms, and duration of GERD. One death (0.07%) occurred. At 3 months, there were no differences among the three groups concerning conversion, morbidity, dysphagia, early reintervention, or postoperative length of stay. The length of surgery was more important in the Toupet procedure. In the Nissen group, there were fewer Visick grade I patients but more Visick grade III patients. At 2 years, the recurrence and reintervention rates were similar. The overall residual severe dysphagia rate was 0.35% (n = 5). In the Nissen group, there were fewer Visick grade I patients but more in Visick grade II patients. There was no difference in Visick grade III and IV among the groups. More than 90% of the patients were satisfied (Visick I + Visick II), with no significant difference among the three groups. The results of this study do not differ significantly from the data reported in the literature, suggesting such surgical techniques are effective and well tolerated, and that both can be properly used in the treatment of GERD.

  6. [Life and work of the surgeon Ernst von Bergmann (1836-1907), long-term editor of the "Zentralblatt für Chirurgie"].

    PubMed

    Zimmermann, M

    2000-01-01

    Ernst von Bergmann (* December 16, 1836 at Riga- [symbol: see text] March 25, 1907 at Wiesbaden) was one of the most famous and successful surgeons in Europe at the end of the 19th century. Having passed his medical education at the University of Dorpat/Latvia he did his doctorate on a pharmacological subject and habilitated as a young assistant already in 1863 with a well-founded experimental study on animals to the question of fat embolism. The voluntary participation as medical officer in three wars (1866, 1870/71, 1877/78) gave him the qualification to express important logistic conditions for the case of vast numbers of wounded soldiers, to demand an increased deployment of better trained ancillary and nursing staff as well as to establish a modified procedure for the treatment of gunshot wounds, particulary of the joints and the skull. In his position as regular professor and head of the surgical department at the Universities of Dorpat (1871-1878), Würzburg (1878-1882) and Berlin (1882-1907) he redressed quickly architectural and infrastructural mismanagements despite of complex obstacles, spoke up for a diversified education of the students he has been entrusted with, supported untiringly the career path of his collaborators and published a huge number of internationally approved scientific articles. In addition to his very time-consuming clinical activities, which even took him to the highest social classes, von Bergmann became initiator of the surgical asepsis and developed operative methods valid up to this day in traumatology, abdominal, tumour and, above all, in neurological surgery. Being member or chairman of different medical associations and editor of prestigious periodicals, he started an effective post-graduate training for interested colleagues and arranged the first qualified exhaustive rescue service in the German capital.

  7. La trochantérite tuberculeuse, un diagnostic souvent difficile

    PubMed Central

    Mhammdi, Younes; Boufettal, Moncef; Kharmaz, Mohamed; Lahlou, Abdou; Mahfoud, Mustapha; EL Bardouni, Ahmed; Berrada, Mohamed Saleh

    2016-01-01

    La trochantérite tuberculeuse est une affection rare (<2% des tuberculoses ostéo-articulaires), même en pays à forte endémie, elle est caractérisée par une symptomatologie insidieuse rendant souvent son diagnostic tardif. Les auteurs rapportent une série de 9 cas, le diagnostic a été posé sur des études bactériologiques et histologiques après un bilan d'imagerie (échographie, IRM, TDM). Le traitement de cette affection est médical (antibiothérapie antituberculeuse), et la chirurgie ne trouve sa place qu'en cas de complications et permet d'améliorer l’évolution. PMID:27279938

  8. L'hémangiopéricytome méningé: une tumeur intracrânienne rare - à propos d'un cas

    PubMed Central

    Errachdi, Amal; Asabbane, Amal; Epala, Brice Nkoua; Hemmich, Mariem; Kabbali, Naoual; Diakité, Adama; Kebdani, Tayeb; Benjaafar, Noureddine

    2014-01-01

    L'hémangiopéricytomeméningé intracrânien est une tumeur rare qui représente moins de 1% des tumeurs cérébrales. Son aspect radiologique peut être trompeur et faire porter à tort le diagnostic de méningiome. Le diagnostic de confirmation est histologique. Le traitement repose sur la chirurgie et la radiothérapie. L’évolution après traitement est caractérisée par la fréquence des récidives et des métastases à distance, imposant un suivi prolongé. Nous rapportons l'observation d'un patient présentant un hémangiopéricytome intracrânien dont l’évolution était marquée par l'absence de récidive à 4 ans de suivi. PMID:25170367

  9. Tumeur phyllode chez une jeune adolescente de 12 ans: à propos d’un cas et revue de la littérature

    PubMed Central

    Issara, Karima; Houjami, Majdouline; Sahraoui, Souha; Bouchbika, Zineb; Benchakroun, Nadia; Jouhadi, Hassan; Tawfiq, Nezha; Benider, Abdellatif

    2016-01-01

    Les tumeurs phyllodes du sein sont des tumeurs très rares et restent exceptionnelles chez les enfants et les adolescents, leurs traitement est basé sur la chirurgie et la radiothérapie, avec un bon pronostic. Nous rapportons le cas d'une adolescente âgée de 12 ans, qui s'est présentée pour une masse du sein gauche. Le diagnoctic d'une tumeur phyllode a été retenu après bilan et histologie. Le traitement a consisté en une tumorectomie large sans traitement adjuvant ; avec une bonne évolution à un recul de deux ans. PMID:28154712

  10. Paragangliome rétropéritonéal non secrétant: une cause rare d'occlusion intestinale haute

    PubMed Central

    Soufi, Mehdi; Benamr, Said; Chad, Bouziane

    2014-01-01

    Les paragangliomes sont des tumeurs neuroendocrines rares diagnostiquées le plus souvent chez le jeune adulte. Nous rapportons le cas rare d'une jeune femme de 20 ans présentant un paragangliome rétropéritonéal situé sur la face antérolatérale de l'aorte et comprimant l'angle duodéno-jéjunal responsable d'un syndrome subocclusif haut. Dans les formes non sécrétantes, la symptomatologie est souvent déroutante. Le diagnostic n'est généralement fait qu'après examen histologique de la pièce de résection. Le traitement de choix repose sur une chirurgie carcinologique intégrant une concertation multidisciplinaire. PMID:25469205

  11. Papillome inversé: étude rétrospective à propos de 22 cas

    PubMed Central

    Chihani, Mehdi; Nadour, Karim; Touati, Mohamed; Darouassi, Youssef; Ammar, Haddou; Bouaity, Brahim

    2014-01-01

    Le papillome inversé est une tumeur bénigne naso-sinusienne rare, marquée par une forte agressivité locale, un taux élevé de récidive après chirurgie et un risque imprévisible d'association à un carcinome épidermoïde. Il s'agit d'une étude rétrospective de 22 cas de papillome inversé, colligés entre janvier 2000 et décembre 2012 au service d'oto-rhino-laryngologie et chirurgie cervico-faciale de l'hôpital militaire Avicenne de Marrakech. L'objectif de ce travail est d’étudier le profil épidémiologique, clinique, endoscopique, radiologique, thérapeutique et évolutif du papillome inversé. Le sex-ratio a été de 3,7 en faveur du sexe masculin avec une moyenne d’âge de 44 ans et un pic de fréquence entre la quatrième et la cinquième décade. Les symptômes cliniques ont été dominés par l'obstruction nasale. Le bilan radiologique faisant appel au couple TDM et IRM naso-sinusiennes constitue un moyen essentiel pour le diagnostic positif et dans choix de la technique opératoire. La voie vestibulaire sous labiale de Rouge Denker a été utilisée chez 4 patients, 12 patients ont bénéficié d'une chirurgie endoscopique endonasale et 6 patients d'une combinaison des deux voies précédentes. Cinq patients ont eu une récidive du papillome inversé, après un délai moyen de 26 mois. PMID:25161752

  12. Chronic effects of JP-8 jet-fuel exposure on the lungs. Annual report, 1 Apr 91-1 Apr 92

    SciTech Connect

    Witten, M.L.

    1992-04-23

    This research has resulted in four separate projects. The first was the exposure of Fischer 344 rats to JP-8 jet fuel for 7 or 28 days. This exposure resulted in changes in pulmonary function and lung chemical mediators, specifically Substance P, after 28 days of exposure. The second project dealt with blocking the increase in SP in these rats by a pretreatment regimen with capsaicin before jet fuel exposure. Capsaicin caused a further increase in lung permeability and a million-fold increase in airway sensitivity to histamine after the 7-day jet fuel exposure. The third project dealt with the effects of a 7-day jet fuel exposure in congenic mice who are deficient in the inducibility of the aryl hydrocarbon hydroxylase enzyme. These mice are relatively resistant to the effects of jet fuel-induced lung injury. The fourth project investigated the effects of the jet fuel exposure on secondary organs, specifically the liver, spleen, and kidneys. There were pathological differences in the liver, spleen, and kidneys between the 7-day jet fuel exposure group and baseline controls. However, some of these differences were not apparent in the 28-day exposure group, possibly indicating compensatory mechanisms to the exposure.

  13. Lead detection and mapping with reference to relationships between scale, sensor characteristics, surface conditions, and atmospheric properties. Annual report, 15 Apr 91-14 Apr 92

    SciTech Connect

    Key, J.; Stone, R.S.; Maslanik, J.A.; Ellefsen, E.

    1992-04-20

    During the first two years of the project, empirical studies of scale relationships in the retrieval of sea ice lead statistics have been undertaken, as have modeling investigations of atmospheric influences on the satellite signal. Additionally, we have developed statistical models that describe the scaling properties of leads. The empirical studies have been based primarily on comparisons within and between Landsat and AVHRR imagery, while the atmospheric models have been specific to the AVHRR. Submarine sonar data have been used in the statistical model development. Specific accomplishments to date include: The parameterizations of clouds, haze, and atmospheric chemical constituents in the LOWTRAN 7 radiative transfer model have been reviewed. Atmospheric temperature and humidity profiles for the arctic have been constructed from Soviet ice island data and are being used in the model. Resampling methods have been tested on simulated, AVHRR, and Landsat images, as have the effects of digital enhancements. Procedures for the retrieval of lead statistics have been developed and applied to Landsat imagery successively degraded to more coarse resolutions.

  14. Radio-chimiothérapie adjuvante des adénocarcinomes gastriques: à propos de 34 cas et d'une revue de la literature

    PubMed Central

    James, Laurianne; Dossou, Sepos; Bellfiq, Sarah; Irigo, Joëlle; Ogandaga, Etienne; Mouden, Karima; Loughmari, Saïda; Filali, Dounia; El Majjaoui, Sanaa; Kebdani, Tayeb; Ahid, Samir; Benjafaar, Nourredine

    2014-01-01

    Notre étude consistera en l’évaluation du pronostic des patients porteurs d'un adénocarcinome gastrique opérés et traités par radio-chimiothérapie adjuvante en technique conformationnelle. Entre Janvier 2007 et Décembre 2011, 34 patients ont reçu après une chirurgie radicale (R0 ou R1), un à trois cycles de 5-Fluoro-uracile associé à de l'Elvorine en adjuvant, suivi d'une radio-chimiothérapie selon le même protocole à la dose de 45Gy, puis de deux cycles de chimiothérapie à un mois d'intervalle après la radio-chimiothérapie concomitante. Dans le groupe d’étude, il y avait 34 patients d’âge médian 50 ans (47-58), avec un sexe ratio (H/F) de 2,4. Une chirurgie de type R1 a été réalisée dans 26,5% des cas, et 53% des patients étaient de stade III-IV. Le rapport nombres de ganglions positifs, sur nombre de ganglions prélevés étaient > 0,4 dans 26,5% des cas. Durant le traitement mené à terme, une neutropénie de grade III a été observée chez quatre patients, avec des troubles digestifs (nausées, vomissement, ou diarrhée) de grade I/II dans la majorité des cas. Après un suivi médian de 20 mois, 70,6% des patients étaient en survie sans rechute, et 29,4% ont présenté une récidive métastatique; la survie globale à 5 ans était de 35,4% et la survie sans progression de 58,7%. La radio-chimiothérapie concomitante postopératoire pourrait être un régime efficace et sûre chez les patients ayant bénéficié d'une gastrectomie à visée curative dans le cancer de l'estomac localement avancé. PMID:25709728

  15. Novel optoelectronic devices; Proceedings of the Meeting, The Hague, Netherlands, Mar. 31-Apr. 2, 1987

    NASA Technical Reports Server (NTRS)

    Adams, Michael J. (Editor)

    1987-01-01

    The present conference on novel optoelectronics discusses topics in the state-of-the-art in this field in the Netherlands, quantum wells, integrated optics, nonlinear optical devices and fiber-optic-based devices, ultrafast optics, and nonlinear optics and optical bistability. Attention is given to the production of fiber-optics for telecommunications by means of PCVD, lifetime broadening in quantum wells, nonlinear multiple quantum well waveguide devices, tunable single-wavelength lasers, an Si integrated waveguiding polarimeter, and an electrooptic light modulator using long-range surface plasmons. Also discussed are backward-wave couplers and reflectors, a wavelength-selective all-fiber switching matrix, the impact of ultrafast optics in high-speed electronics, the physics of low energy optical switching, and all-optical logical elements for optical processing.

  16. Race to the Top. Massachusetts. State-Reported APR: Year One

    ERIC Educational Resources Information Center

    US Department of Education, 2012

    2012-01-01

    This paper describes Massachusetts' progress in implementing a comprehensive and coherent approach to education reform from the time of application through June 30, 2011. In particular, it highlights key accomplishments over the reporting period in the four reform areas: standards and assessments, data systems to support instruction, great…

  17. Race to the Top. District of Columbia. State-Reported APR: Year One

    ERIC Educational Resources Information Center

    US Department of Education, 2012

    2012-01-01

    This paper describes the District of Columbia's progress in implementing a comprehensive and coherent approach to education reform from the time of application through June 30, 2011. In particular, this report highlights key accomplishments over the reporting period in the four reform areas: standards and assessments, data systems to support…

  18. The Port Moresby-Solomons Operation and the Allied Reaction, 27 Apr - 11 May 1942

    DTIC Science & Technology

    2012-01-01

    started their attack, giving most of their attention to Lexington. Yorktown received one bomb hit, but Lexington was struck by two tor- pedoes and two...bombers, and thirty tor- pedo bombers) and 1,074 men; the Allies lost sixty-six aircraft and 543 men.235 One Japanese large carrier was heavily damaged

  19. Symposium on Electromagnetic Launcher Technology, 5th, Sandestin, FL, Apr. 3-5, 1990, Proceedings

    NASA Astrophysics Data System (ADS)

    Gooden, Clarence E.

    1991-01-01

    The present conference on electromagnetic accelerators (EMAs) and railguns (RGs) discusses active-current management for four-rail RGs, the design of a compulsator-drive 60-caliber RG, EMA studies with augmented rails, muzzle-shunt augmentation of conventional RGs, effect of in-bore gas on RG performance, the distributed-energy store RG, plasma diagnostics for high power ignitron development, a review of EMA armature research, RG hybrid armatures, a new solid-armature design concept, and the electrodynamics of RG plasma armatures. Also discussed is RG modeling at speed using three-dimensional finite elements, power supply technology for EMAs, rotating machine power supplies for next-generation EMAs, advanced EMA power supplies with magnetic-flux compression, metal-to-metal switches for large currents, lightweight high-effiency energy-storage transformers, hypervelocity projectile development for EMAs, structural design issues for EMA projectiles, stiff RGs, a reinforced Al conductor for cryogenic applications, mass-stabilized projectile designs for EMA launch, indictively-commutated coilguns, an actively switched pulsed induction accelerator, a plasma gun-augmented electrothermal accelerator, a symmetrical rail accelerator, and a travelling-wave synchronous coil gun.

  20. International Instrumentation Symposium, 38th, Las Vegas, NV, Apr. 26-30, 1992, Proceedings

    NASA Astrophysics Data System (ADS)

    The present volume on aerospace instrumentation discusses computer applications, blast and shock, implementation of the Clean Air Act amendments, and thermal systems. Attention is given to measurement uncertainty/flow measurement, data acquisition and processing, force/acceleration/motion measurements, and hypersonics/reentry vehicle systems. Topics addressed include wind tunnels, real time systems, and pressure effects. Also discussed are a distributed data and control system for space simulation and thermal testing a stepwise shockwave velocity determinator, computer tracking and decision making, the use of silicon diodes for detecting the liquid-vapor interface in hydrogen, and practical methods for analysis of uncertainty propagation.

  1. Race to the Top. Georgia. State-Reported APR: Year One

    ERIC Educational Resources Information Center

    US Department of Education, 2012

    2012-01-01

    This paper describe Georgia's progress in implementing a comprehensive and coherent approach to education reform from the time of application through June 30, 2011. In particular, it highlights key accomplishments over the reporting period in the four reform areas: standards and assessments, data systems to support instruction, great teachers and…

  2. Advances in optical structure systems; Proceedings of the Meeting, Orlando, FL, Apr. 16-19, 1990

    NASA Astrophysics Data System (ADS)

    Breakwell, John; Genberg, Victor L.; Krumweide, Gary C.

    Various papers on advances in optical structure systems are presented. Individual topics addressed include: beam pathlength optimization, thermal stress in glass/metal bond with PR 1578 adhesive, structural and optical properties for typical solid mirror shapes, parametric study of spinning polygon mirror deformations, simulation of small structures-optics-controls system, spatial PSDs of optical structures due to random vibration, mountings for a four-meter glass mirror, fast-steering mirrors in optical control systems, adaptive state estimation for control of flexible structures, surface control techniques for large segmented mirrors, two-time-scale control designs for large flexible structures, closed-loop dynamic shape control of a flexible beam. Also discussed are: inertially referenced pointing for body-fixed payloads, sensor blending line-of-sight stabilization, controls/optics/structures simulation development, transfer functions for piezoelectric control of a flexible beam, active control experiments for large-optics vibration alleviation, composite structures for a large-optical test bed, graphite/epoxy composite mirror for beam-steering applications, composite structures for optical-mirror applications, thin carbon-fiber prepregs for dimensionally critical structures.

  3. Sensor fusion III; Proceedings of the Meeting, Orlando, FL, Apr. 19, 20, 1990

    SciTech Connect

    Harney, R.C.

    1990-01-01

    Multisensor image segmentation algorithms, scene descriptions from radar and infrared images, and combination of evidences with dependency information in distributed sensor systems are discussed. Preference voting for sensor fusion, a simulation-based test bed for data-association algorithms, receiver operating characteristics for various sensor fusion schemes, and adaptive multisensor change detection are analyzed. A tree-structured sensor fusion architecture for distributed sensor networks and performance modeling of multisensor networks is covered, along with components for sensor fusion systems, including high-precision line-of-sight stabilization for a 1-m space telescope with onboard image processing. The continuous mode of operation of a space-time light modulator is addressed, as well as an embedded knowledge-based system for automatic target recognition and multisensor data fusion for mine detection.

  4. Design study of small efficient cryocoolers. Final technical report 14 Apr-11 Sep 80

    SciTech Connect

    Sereny, A.; Daniels, A.

    1980-11-01

    A triple-expansion Stirling-cycle refrigerator driven by a linear mechanism was the configuration selected to best meet the requirements of this Phase I design study for a small, low-power, light-weight, efficient, closed-cycle cryocooler. The specifications for the cooling of superconductive magnetometers require the cryogenic refrigerator to operate at 10 degrees K or less with a heat load of 50 mW, have an electrical input power not exceeding 250 W, and have minimum mechanical motion and magnetic signatures. The results of this design study indicate that the 50 mW of refrigeration at 10 degrees K with a maximum power input of 250 W can be readily met with a free-displacer, free-piston system. Three problem areas were identified and analyzed, viz., the lead regenerator matrix, piston seals, and output-temperature fluctuations. An analysis was also made of the magnetic effects of mechanical motion. This report concludes with an outline of the proposed efforts for a Phase II program.

  5. Infrared detectors and focal plane arrays; Proceedings of the Meeting, Orlando, FL, Apr. 18, 19, 1990

    NASA Astrophysics Data System (ADS)

    Dereniak, Eustace L.; Sampson, Robert E.

    1990-09-01

    The papers contained in this volume provide an overview of recent advances and the current state of developments in the field of infrared detectors and focal plane arrays. Topics discussed include nickel silicide Schottky-barrier detectors for short-wavelength infrared applications; high performance PtSi linear and focal plane arrays; and multispectral band Schottky-barrier IRSSD for remote-sensing applications. Papers are also presented on the performance of an Insi hybrid focal array; characterization of IR focal plane test stations; GaAs CCD readout for engineered bandgap detectors; and fire detection system for aircraft cargo bays.

  6. Engineer: The Professional Bulletin of Army Engineers, Jan-Apr 2010

    DTIC Science & Technology

    2010-04-01

    do not necessarily reflect of- ficial U.S. Army positions and do not change or supersede information in other U.S. Army publications. Use of news ...Diana M. Holland 18 Engineers Build Capacity in Stability Operations By Colonel Jeffrey R. Eckstein 21 Army Training Support Enterprise: A New Paradigm...turnout of enlisted engineer leaders at ENFORCE 2010. It’s a great opportunity to rekindle old friendships and create new ones. Our experiences over

  7. Race to the Top. New York. State-Reported APR: Year One

    ERIC Educational Resources Information Center

    US Department of Education, 2012

    2012-01-01

    This paper describes New York's progress in implementing a comprehensive and coherent approach to education reform from the time of application through June 30, 2011. In particular, this report highlights key accomplishments over the reporting period in the four reform areas: standards and assessments, data systems to support instruction, great…

  8. AIAA Dynamics Specialists Conference, Dallas, TX, Apr. 16, 17, 1992, Technical Papers

    SciTech Connect

    Not Available

    1992-01-01

    This conference presents papers in the fields of spacecraft dynamics, the control of structures, the active flexible wing, flutter characteristics, and rotary-wing aeroelasticity. Also considered are control-structure interaction, unsteady aerodynamics, fixed-wing aeroelasticity, structural dynamics systems, and CSI-sensors and actuators.

  9. Earth and atmospheric remote sensing; Proceedings of the Meeting, Orlando, FL, Apr. 2-4, 1991

    NASA Technical Reports Server (NTRS)

    Curran, Robert J. (Editor); Smith, James A. (Editor); Watson, Ken (Editor)

    1991-01-01

    The papers presented in this volume address the technical aspects of earth and atmospheric remote sensing. Topics discussed include spaceborne and ground-based applications of laser remote sensing, advanced applications of lasers in remote sensing, laser ranging applications, data analysis and systems for biospheric processes, measurements for biospheric processes, and remote sensing for geology and geophysics. Papers are presented on a space-qualified laser transmitter for lidar applications, solid state lasers for planetary exploration, automated band selection for multispectral meteorological applications, aerospace remote sensing of natural water organics, and remote sensing of volcanic ash hazards to aircraft.

  10. The 8th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2012

    2012-01-01

    In classrooms around the country, AP (Advanced Placement) teachers are preparing students for tomorrow by teaching them how to think and learn today. AP students learn to construct solid arguments, test theories, and see many sides of an issue--the kind of thinking that solves tough problems both in and outside the classroom, in college and…

  11. USSR Report, Political and Sociological Affairs, Peoples of Asia and Africa, No. 2, Mar - Apr 1985.

    DTIC Science & Technology

    1985-08-30

    today. The stereotype of the unhurried Arab sheikh enjoying the joys of life in the desert or in Western casinos while his incomes from oil are...surmounting of ideas of the primitive state of African peoples which has been taking place in the last decade and Eurocentrism in the approach to dividing

  12. Analysis of Parent Survey Data Addressing Part B SPP/APR Indicator #8--2012

    ERIC Educational Resources Information Center

    Penfield, Randall D.

    2012-01-01

    In accordance with federal reporting requirements mandated by the U.S. Department of Education, Office of Special Education Programs (OSEP) under the Individuals with Disabilities Education Act, the Bureau of Indian Education (BIE) must report annually on 20 performance indicators related to the provision of special education services to children…

  13. Analysis of Parent Survey Data Addressing Part B SPP/APR Indicator #8--2011

    ERIC Educational Resources Information Center

    Penfield, Randall D.

    2011-01-01

    In accordance with federal reporting requirements mandated by the U.S. Department of Education, Office of Special Education Programs (OSEP) under the Individuals with Disabilities Education Act, the Bureau of Indian Education (BIE) must report annually on 20 performance indicators related to the provision of special education services to children…

  14. Analysis of Parent Survey Data Addressing Part B SPP/APR Indicator #8--2013

    ERIC Educational Resources Information Center

    Penfield, Randall D.

    2013-01-01

    In accordance with federal reporting requirements mandated by the U.S. Department of Education, Office of Special Education Programs (OSEP) under the Individuals with Disabilities Education Act, the Bureau of Indian Education (BIE) must report annually on 20 performance indicators related to the provision of special education services to children…

  15. Visual information processing; Proceedings of the Meeting, Orlando, FL, Apr. 20-22, 1992

    NASA Technical Reports Server (NTRS)

    Huck, Friedrich O. (Editor); Juday, Richard D. (Editor)

    1992-01-01

    Topics discussed in these proceedings include nonlinear processing and communications; feature extraction and recognition; image gathering, interpolation, and restoration; image coding; and wavelet transform. Papers are presented on noise reduction for signals from nonlinear systems; driving nonlinear systems with chaotic signals; edge detection and image segmentation of space scenes using fractal analyses; a vision system for telerobotic operation; a fidelity analysis of image gathering, interpolation, and restoration; restoration of images degraded by motion; and information, entropy, and fidelity in visual communication. Attention is also given to image coding methods and their assessment, hybrid JPEG/recursive block coding of images, modified wavelets that accommodate causality, modified wavelet transform for unbiased frequency representation, and continuous wavelet transform of one-dimensional signals by Fourier filtering.

  16. 48 CFR 1552.235-79 - Release of contractor confidential business information (APR 1996).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    .... 7401 et seq.); the Federal Water Pollution Control Act (33 U.S.C.1251 et seq.); the Safe Drinking Water... employees engaged in information systems analysis, development, operation, and maintenance, including...

  17. Military Review: The Professional Journal of the U.S. Army, Mar-Apr 2011

    DTIC Science & Technology

    2011-04-01

    instability.37 Approximately 18 percent of Mexicans live in poverty in terms of access to food , while 47 percent live in poverty with respect to...35. 13. K.D. Gott (2006), Breaking the Mold : Tanks in the Cities (Fort Leavenworth, KS: Combat Studies Institute Press), 97. 14. Donn Starry, “U.S...cordite smell , blasts, rifle cracks, screams, and camaraderie, knowing that some among them will lose limbs or bleed out. They don’t need a

  18. Ventilation host and risk area techniques. Final report Aug 80-Apr 82

    SciTech Connect

    York, S.B. III; Reeves, R.J.; Wallace, R.J.

    1982-04-01

    This study consisted of an investigation into several aspects of providing ventilation in counterforce risk- and host-area shelter facilities. Ventilation concepts, including the characteristics of methods for providing ventilation and the shelter characteristics affecting ventilation, were reviewed. Ventilation kit requirements were developed as a function of shelter ventilating characteristics. In defining ventilation kit requirements, optimal ventilation kit deployment (so as to minimize the number of devices required per shelter story) was assumed. Data derived from the NSS-CRP Master File and from a sample of NSS shelter facilities were employed to define the ventilating characteristics of the shelter facilities in each counterforce risk and host county. These data then were used along with pertinent counterforce risk- and host-area characteristics (shelter requirements and zonal ventilation requirements) to estimate the ventilation kit requirements by county, counterforce area, and FEMA Region. Estimates were computed under both 'best case' and 'worst case' assumptions. Under the 'best case' assumption, wind driven ventilation could deliver 8,692 cfm to any aboveground story. No shelter story could be adequately ventilated by wind-driven ventilation under the 'worst case' assumption. In computing the ventilation kit requirements, the numbers of shelter stories requiring no ventilation devices, only Kearny pumps, only PVKs, and combinations of Kearny pumps and PVKs were compiled.

  19. Method development study for APR cartridge evaluation in fire overhaul exposures.

    PubMed

    Anthony, T Renée; Joggerst, Philip; James, Leonard; Burgess, Jefferey L; Leonard, Stephen S; Shogren, Elizabeth S

    2007-11-01

    In the US, firefighters do not typically wear respiratory protection during overhaul activities, although fitting multi-gas or chemical, biological, radiological and nuclear cartridges to supplied air respirator facepieces has been proposed to reduce exposures. This work developed a method to evaluate the effectiveness of respirator cartridges in smoke that represents overhaul exposures to residential fires. Chamber and penetration concentrations were measured for 91 contaminants, including aldehydes, polynuclear aromatic hydrocarbons, hydrocarbons and methyl isothiocyanate, along with total and respirable particulates. These laboratory tests generated concentrations in the range of field-reported exposures from overhaul activities. With limited tests, no styrene, benzene, acrolein or particulates were detected in air filtered by the respirator cartridge, yet other compounds were detected penetrating the respirator. Because of the complexity of smoke, an exposure index was determined for challenge and filtered air to determine the relative risk of the aggregate exposure to respiratory irritants. The primary contributors to the irritant exposure index in air filtered by the respirator were formaldehyde and acetaldehyde, with total hydrocarbons contributing only 1% to the irritant index. Respirator cartridges were adequate to minimize firefighter exposures to aggregate respiratory irritants if the American Conference of Governmental Industrial Hygienists ceiling limit for formaldehyde is used (0.3 ppm) but not if National Institute for Occupational Safety and Health Recommended Exposure Limit (NIOSH REL) (0.1 ppm) is used, where three of five concentrations in filtered air exceeded the NIOSH REL. Respirator certification allows 1 ppm of formaldehyde to pass through it when challenged at 100 ppm, which may not adequately protect workers to current short-term exposure/ceiling limits. The method developed here recommends specific contaminants to measure in future work (formaldehyde, acrolein, acetaldehyde, naphthalene, benzene, total hydrocarbons as toluene and particulate mass) along with inclusion of additional irritant gases and hydrogen cyanide to fully evaluate whether air-purifying respirators reduce exposures to the aggregate gases/vapors present in overhaul activities.

  20. Modeling of HF propagation and heating in the ionosphere. Final report, Apr 89-Nov 91

    SciTech Connect

    Hinkel, D.; Shoucri, M.; Smith, T.; Wagner, T.

    1992-02-01

    The purpose of the program of research reported here is to develop and demonstrate a realistic numerical model for self-consistent ionospheric propagation and heating of powerful frequency (HF) waves by conjoining existing, separate numerical models for high frequency wave propagation and ionospheric transport. A comprehensive numerical implementation of plasma geometric optics has been enhanced and adapted to the problem of self-consistent ionospheric propagation of high power, high frequency radar signals. The emphasis in this work is on the realistic and rigorous description of the propagation waves so that geometric and spectral characteristics of nonlinear ionospheric effects can be predicted in detail. The plasma geometric optics code has been used in conjunction with an ionospheric transport code to determine self-consistently the HF radiation field and quasilinear modifications of ionospheric plasma properties due to ohmic dissipation of the HF radiation. This allows detailed study of nonlinear phenomena such as beam self-focusing formation of large-scale density cavities and striations, and induced wave ducting. Overviews of the theory underlying the existing models of radiation propagation and ohmic power deposition are given, and enhancements to these models are described. New results achieved using the enhanced models are shown and the treatment of a self-consistent propagation and heating problem is presented.

  1. Advanced techniques for array processing. Final report, 1 Mar 89-30 Apr 91

    SciTech Connect

    Friedlander, B.

    1991-05-30

    Array processing technology is expected to be a key element in communication systems designed for the crowded and hostile environment of the future battlefield. While advanced array processing techniques have been under development for some time, their practical use has been very limited. This project addressed some of the issues which need to be resolved for a successful transition of these promising techniques from theory into practice. The main problem which was studied was that of finding the directions of multiple co-channel transmitters from measurements collected by an antenna array. Two key issues related to high-resolution direction finding were addressed: effects of system calibration errors, and effects of correlation between the received signals due to multipath propagation. A number of useful theoretical performance analysis results were derived, and computationally efficient direction estimation algorithms were developed. These results include: self-calibration techniques for antenna arrays, sensitivity analysis for high-resolution direction finding, extensions of the root-MUSIC algorithm to arbitrary arrays and to arrays with polarization diversity, and new techniques for direction finding in the presence of multipath based on array interpolation. (Author)

  2. APR1400 LBLOCA uncertainty quantification by Monte Carlo method and comparison with Wilks' formula

    SciTech Connect

    Hwang, M.; Bae, S.; Chung, B. D.

    2012-07-01

    An analysis of the uncertainty quantification for the PWR LBLOCA by the Monte Carlo calculation has been performed and compared with the tolerance level determined by Wilks' formula. The uncertainty range and distribution of each input parameter associated with the LBLOCA accident were determined by the PIRT results from the BEMUSE project. The Monte-Carlo method shows that the 95. percentile PCT value can be obtained reliably with a 95% confidence level using the Wilks' formula. The extra margin by the Wilks' formula over the true 95. percentile PCT by the Monte-Carlo method was rather large. Even using the 3 rd order formula, the calculated value using the Wilks' formula is nearly 100 K over the true value. It is shown that, with the ever increasing computational capability, the Monte-Carlo method is accessible for the nuclear power plant safety analysis within a realistic time frame. (authors)

  3. Space Congress, 29th, Cocoa Beach, FL, Apr. 21-24, 1992, Proceedings

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The present volume on the quest for new frontiers in space discusses weather impacts on space operations, planning for the performance of future space bases, a new guidance and control unit for the Titan IV vehicle, and nondestructive evaluation of Shuttle Columbia tiles. Attention is given to Space Shuttle payload accommodations and trends in customer demands, a generic propellants transfer unit, making space part of general education, space station on-orbit solar array loads during assembly, and dimensional stability of the attitude reference assembly on SSF. Topics addressed include National Launch System payload accommodations and launch operations, the integrated factory/launch site processing concept, Pioneer 10 interstellar studies, and the role of advanced nuclear propulsion systems in precursor interstellar missions. Also discussed are legal challenges in realizing interstellar initiatives, Mars transportation system synthesis, and NASA's commercial space program.

  4. Flows of selected hazardous materials by rail. Final report for Sep 87-Apr 91

    SciTech Connect

    Beier, F.; Church, R.; Zebe, P.; Frev, J.

    1991-05-01

    The report is a review of hazardous materials rail traffic in the continental United States. It focuses on the year 1986, a relatively typical recent year in which an estimated total of 1,477 million net tons of freight was moved by rail. Of this, 63 million net tons, or four percent of the total, were hazardous materials. The report is designed to characterize the flow of selected hazardous materials and show their geographical distribution. It focusses on materials that (1) have large tonnages moving by rail, such as Products of Refining, (2) are regarded as especially dangerous, such as Products That May Be Toxic by Inhalation, or (3) have been recently designated as hazardous materials, such as molten or liquid sulphur. Its scope includes national, state and Business Economic Areas (BEAs) rail traffic. The purpose of the report is to help those in government and industry who are interested in the flows of hazardous materials see how these materials are geographically distributed by rail.

  5. Carbon monoxide monitor for automobile passenger compartment. Final report, Jul 90-Apr 91

    SciTech Connect

    Grace, R.; Guzman, A.; Portnoff, M.; Purta, D.

    1991-07-01

    The document reports the results of the study conducted by the Carnegie Mellon Research Institute (CMRI) to evaluate its recently developed metal oxide semiconductor (MOS) gas sensor technology for applications in the automobile environment. The specific use of the technology is for a low-cost carbon monoxide (CO) monitor to be placed in the automobile compartment to protect the driver and passengers. The approach followed in the study was first, to define the physical and chemical characteristics of the vehicle's compartment and the surrounding environment; second, to evaluate the effects of these environments on the MOS sensor performance in terms of sensitivity, selectivity and stability. The comparison of the chemical environment with MOS sensor data previously collected by CMRI, revealed the feasibility of the technology for CO monitoring in cars and other highway vehicles. Preliminary designs of the sensor chip, filter and electronics are presented in the document.

  6. Applications of artificial intelligence VI; Proceedings of the Meeting, Orlando, FL, Apr. 4-6, 1988

    SciTech Connect

    Trivedi, M.M.

    1988-01-01

    Papers are presented on architectures for AI applications, schemes for image understanding, knowledge-based systems, image segmentation and analysis, expert systems, and uncertainty management. Also considered are computational vision, syntactic learning, three-dimensional vision schemes involving shape recovery and analysis, computer vision models and applications, and parallel architectures. Other topics include path planning, robotic systems, target detection and image understanding, natural language systems, and knowledge acquisition and representation.

  7. Thermosense XIII; Proceedings of the Meeting, Orlando, FL, Apr. 3-5, 1991

    NASA Astrophysics Data System (ADS)

    Baird, George S.

    The present conference on thermosensing technologies discusses topics in predictive maintenance, architectural and structural applications, product and processing applications, material diagnostics, and laboratory researches. Attention is given to IR thermography for pipeline leak detection, thermal analyses of masonry block buildings during construction, thermography for electronic component lifetime prediction, time-resolved videothermography, and vibrothermographic-thermoelastic NDE of advanced composites. Also discussed are pulse-video thermography, time-resolved IR radiometry, quantitative thermal gradient imaging, automated image processing of IR thermography, and algorithms for IR pyrometry.

  8. Research, development, and demonstration of algal production raceway (APR) systems for the production of hydrocarbon resources

    SciTech Connect

    Laws, E.A.

    1984-02-01

    A fractional factorial experimental design was used to determine the maximum production and photosynthetic efficiency that could be achieved in shallow algal mass culture systems (SAMCS) of the marine diatom Phaeodactylum tricornutum. Dilution rate and CO/sub 2/ supply were found to be the most important system parameters. Maximum production was found to be about 25 g dry wt m/sup -2/d/sup -1/. This production corresponded to a photosynthetic efficiency of 5.6%. These figures are 50 to 100% better than the production rates achieved in earlier P. tricornutum cultures using conventional culture techniques. The results are consistent with a theoretical model of the impact of the flashing light effect on algal mass culture production. This model predicts that at the typical irradiances in Hawaii, full utilization of the flashing light effect should enhance production by 70% to over 200%. It was concluded that the use of foil arrays in the experimental flume creates systematic vertical mixing on a time scale suitable for utilizing the flashing light effect. Production of P. tricornutum culture is probably limited by temperature. P. tricornutum cannot survive at temperatures in excess of 25/sup 0/C in outdoor mass cultures. Growth of mesophilic species in the temperature range 30 to 35/sup 0/C may well result in even higher production than that achieved with P. tricornutum.

  9. The 7th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2011

    2011-01-01

    This report shows how well educators across the United States have increased access to the types of rich academic experiences that prepare students for success in college. By combining national, state and AP (Advanced Placement) data, this report provides educators and policymakers with information they can use to celebrate their successes,…

  10. Fibre optics '90; Proceedings of the Meeting, London, England, Apr. 24-26, 1990

    NASA Astrophysics Data System (ADS)

    McGeehin, P.

    The present conference on fiber optics emphasizes the use of components, devices, and materials for hostile environments, and also encompasses applications of optoelectronics in sensors, communications, 'white light' interferometry, the properties of monomode optical fibers, and coherent optical systems. Specific issues addressed include erbium-doped fiber amplifiers in communications, the use of optical amplification in communication, optical fibers in the adverse space environment, the effects of temperature variations on loose-tube and tight-buffered optical fiber cables, and radiation effects in polarization-maintaining fibers. Also addressed are methods to test the effects of high-ionizing-radiation dose rates on optical fiber data links, sensors for meteorological data acquisition, sensor technology for smart structure development, radiative ignition by loose agglomerates of fine fibers, and a multipurpose evanescent mode-coupling-based device.

  11. The 8th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2012

    2012-01-01

    In classrooms around the country, AP (Advanced Placement) teachers are preparing students for tomorrow by teaching them how to think and learn today. AP students learn to construct solid arguments, test theories, and see many sides of an issue--the kind of thinking that solves tough problems both in and outside the classroom, in college and…

  12. Remote sensing of atmospheric chemistry; Proceedings of the Meeting, Orlando, FL, Apr. 1-3, 1991

    NASA Technical Reports Server (NTRS)

    Mcelroy, James L. (Editor); Mcneal, Robert J. (Editor)

    1991-01-01

    The present volume on remote sensing of atmospheric chemistry discusses special remote sensing space observations and field experiments to study chemical change in the atmosphere, network monitoring for detection of stratospheric chemical change, stratospheric chemistry studies, and the combining of model, in situ, and remote sensing in atmospheric chemistry. Attention is given to the measurement of tropospheric carbon monoxide using gas filter radiometers, long-path differential absorption measurements of tropospheric molecules, air quality monitoring with the differential optical absorption spectrometer, and a characterization of tropospheric methane through space-based remote sensing. Topics addressed include microwave limb sounder experiments for UARS and EOS, an overview of the spectroscopy of the atmosphere using an FIR emission experiment, the detection of stratospheric ozone trends by ground-based microwave observations, and a FIR Fabry-Perot spectrometer for OH measurements.

  13. Race to the Top. Rhode Island. State-Reported APR: Year One

    ERIC Educational Resources Information Center

    US Department of Education, 2012

    2012-01-01

    This paper describes Rhode Island's progress in implementing a comprehensive and coherent approach to education reform from the time of application through June 30, 2011. In particular, this report highlights key accomplishments over the reporting period in the four reform areas: standards and assessments, data systems to support instruction,…

  14. Space Congress, 26th, Cocoa Beach, FL, Apr. 25-28, 1989, Proceedings

    SciTech Connect

    Not Available

    1989-01-01

    The papers presented in this volume provide an overview of new programs in space research, including a new beginning for the manned space flight, a rebirth of expendable vehicles, and commercialization of space exploration. Topics discussed include the next generation of STS, national space programs, space enterprise development, commercial space transportation, technology benefits, and the international aspect of Space Station. Attention is also given to state initiatives in space, launch responsiveness, offshore space launch developments, and Shuttle and Space Station scientific payloads and their role in the next generation.

  15. Optical pattern recognition III; Proceedings of the Meeting, Orlando, FL, Apr. 21, 22, 1992

    NASA Technical Reports Server (NTRS)

    Casasent, David P. (Editor); Chao, Tien-Hsin (Editor)

    1992-01-01

    Consideration is given to transitioning of optical processing into systems (TOPS), optical correlator hardware, phase-only optical correlation filters, optical distortion-invariant correlation filters, and optical neural networks. Particular attention is given to a test target for optical correlators, a TOPS electronic warfare channelizer program, a portable video-rate optical correlator, a joint transform correlator employing electron trapping materials, a novelty filtered optical correlator using a photorefractive crystal, a comparison of correlation performance of smart ternary phase-amplitude filters with gray-scale and binary input scenes, real-time distortion-tolerant composite filters for automatic target identification, landscaping the correlation surface, fast designing of a circular harmonic filter using simulated annealing, feature-based correlation filters for distortion invariance, automatic target recognition using a feature-based optical neural network, and a holographic inner-product processor for pattern recognition.

  16. Light water reactor safety research program. Volume 12: quarterly report, Apr-Jun 79

    SciTech Connect

    Berman, M.

    1980-05-01

    This report summarizes the progress of the Light Water Reactor Safety Research Program during the 2nd quarter of 1979. Specifically, the report summarizes progress in five major areas of research. They are: (1) the molten core/concrete interactions study; (2) steam explosion research phenomena; (3) statistical LOCA analysis; (4) UHI model development; (5) two-phase jet loads.

  17. Thin film technologies II; Proceedings of the Meeting, Innsbruck, Austria, Apr. 15-17, 1986

    NASA Astrophysics Data System (ADS)

    Jacobsson, J. Roland

    1986-01-01

    Papers are presented on automated optical coating processes and thin film production with an optical thickness monitoring system; the ultrasonic precision cleaning of optical components prior to and after vacuum coating; a wideband antireflection coating design by the random search approach; a computer-aided design of thin film optical coatings; subjective and objective methods for surface inspection; and micro/ultramicro hardness measurements with insulating films. Topics discussed include optical absorption in amorphous semiconductor films; the optical properties of thin silicide layers; laser damage to optical coatings; and light scattering and characterization of thin films; ion and photon-beam assisted deposition of thin films; and low temperature photo-CVD silicon nitride characterization. Consideration is given to the measurement of absorption in thin films using laser calorimetry; coherence loss due to thin film interface roughness; the performance of sputter deposited multilayer X-ray mirrors; and the stability of hard coating filters.

  18. Iowa. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  19. Alaska. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  20. Ohio. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  1. Maryland. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  2. Pennsylvania. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  3. West Virginia. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  4. Virginia. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  5. Florida. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  6. Delaware. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  7. Rhode Island. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  8. District of Columbia. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  9. Oregon. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  10. Colorado. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  11. Louisiana. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  12. Wisconsin. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  13. South Carolina. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  14. New Mexico. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  15. New Jersey. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  16. Vermont. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  17. Minnesota. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  18. South Dakota. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  19. Race to the Top. Florida. State-Reported APR: Year One

    ERIC Educational Resources Information Center

    US Department of Education, 2012

    2012-01-01

    This paper describes Florida's progress in implementing a comprehensive and coherent approach to education reform from the time of application through June 30, 2011. In particular, it highlights key accomplishments over the reporting period in the four reform areas: standards and assessments, data systems to support instruction, great teachers and…

  20. LANL Water Protection Status Report - FY12 3rd Qtr. (Apr thru Jun 2012)

    SciTech Connect

    Douglass, Craig R.

    2012-07-12

    Continued monitoring of the Buckman Direct Diversion and Los Alamos County Water Supply Wells; Groundwater Protection - Continued implementation of the Interim Facility-Wide Groundwater Monitoring Plan (IFGMP); Surface Water Protection - Continued protection of surface water through implementation of the Individual Stormwater Permit (IP); Buckman Early Notification System operability at 100% per MOU Requirements.

  1. Maine. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  2. New York. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  3. North Dakota. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  4. Nebraska. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  5. Washington. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  6. Connecticut. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  7. Mississippi. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  8. Missouri. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  9. Nevada. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  10. Michigan. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  11. Indiana. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  12. Massachusetts. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  13. Kansas. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  14. Montana. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  15. Oklahoma. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  16. Utah. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  17. Arizona. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  18. California. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  19. Hawaii. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  20. Tennessee. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  1. Kentucky. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  2. Wyoming. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  3. North Carolina. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  4. Illinois. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  5. Alabama. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  6. New Hampshire. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  7. Georgia. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  8. Texas. State Supplement. The 10th Annual AP[R] Report to the Nation

    ERIC Educational Resources Information Center

    College Board, 2014

    2014-01-01

    This report provides educators and policymakers with information they can use to celebrate their successes, understand their unique challenges, and set meaningful goals to increase opportunity for all students. It is important to note that while AP® Exams are valid measures of students' content mastery of college-level studies in specific academic…

  9. Atmospheric processes in reaction of Northern Sumatra Earthquake sequence Dec 2004-Apr 2005

    NASA Astrophysics Data System (ADS)

    Ouzounov, D.; Pulinets, S.; Cervone, G.; Singh, R.; Taylor, P.

    2005-05-01

    This work describes our first results in analyzing data from different and independent sources ûemitted long-wavelength radiation (OLR), surface latent heat flux (SHLF) and GPS Total Electron Content (TEC) collected from ground based (GPS) and satellite TIR (thermal infra-red) data sources (NOAA/AVHRR, MODIS). We found atmosphere and ionosphere anomalies one week prior to both the Sumatra-Andaman Islands earthquake (Dec 26, 2004) and M 8.7 - Northern Sumatra, March 28, 2005. We analyzed 118 days of data from December 1, 2004 through April 1, 2005 for the area (0°-10°,north latitude and 90°-100° east longitude) which included 125 earthquakes with M>5.5. Recent analysis of the continuous OLR from the Earth surface indicates anomalous variations (on top of the atmosphere) prior to a number of medium to large earthquakes. In the case of M 9.0 - Sumatra-Andaman Islands event, compared to the reference fields for the months of December between 2001 and 2004, we found strongly OLR anomalous +80 W/m2 signals (two sigma) along the epicentral area on Dec 21, 2004 five days before the event. In the case of M8.7 March 28, 2005 anomalues signatures over the epicenter appears on March 26 is much weaker (only +20W/m2) and have a different topology. Anomalous values of SHLF associated with M9.0 - Sumatra-Andaman Islands were found on Dec 22, 2005 (SLHF +280Wm2) and less intensity on Mar 23, 2005 (SLHF +180Wm2). Ionospheric variations (GPS/TEC) associated with the Northern Sumatra events were determine by five Regional GPS network stations (COCO, BAKO, NTUS, HYDE and BAST2). For every station time series of the vertical TEC (VTEC) were computed together with correlation with the Dst index. On December 22, four days prior to the M9.0 quake GPS/TEC data reach the monthly maximum for COCO with minor DST activity. For the M 8.7-March 28 event, the increased values of GPS/TEC were observed during four days (March 22-25) in quiet geomagnetic background. Our results need additional validation and the could be explained within the framework of a model of Lithosphere-Atmosphere-Ionosphere coupling, supporting the hypothesis of a relationship between a thermodynamic processes produced by increasing tectonic stresses in the Earth's crust and attendant electro-chemical interactions between the crust and the atmosphere/ionosphere.

  10. Annual Performance Report. FFY 2012. Revised Clarification April 30, 2014. APR Template-Part B.

    ERIC Educational Resources Information Center

    Bureau of Indian Education, 2014

    2014-01-01

    During school year (SY) 2012-2013, the Bureau of Indian Education (BIE) continued its efforts to improve the validity and reliability of data reporting. BIE data collections are dependent on school level entry (self-reporting) into the Native American Student Information System (NASIS) or into the BIE's Academic Report (formerly the BIEs…

  11. USSR Report, Military Affairs, Foreign Military Review, No. 4, Apr 1986

    DTIC Science & Technology

    1986-11-13

    School (Ypenberg) trains senior officers for work in staff positions in Air Force commands and units. Officers of the rank of major, are accepted to...the school , and the course of study is two years. The Korolev Cadet School (Schaarsbergen). Non-commissioned officers are trained at it for specialties...services (the rear, administration, etc.). The Air Force’s Electronic-Technical School (Deelen) trains specialists in the operations of the missile

  12. Remote sensing; Proceedings of the Meeting, Orlando, FL, Apr. 3, 4, 1986

    NASA Technical Reports Server (NTRS)

    Menzies, Robert T. (Editor)

    1986-01-01

    Advances in optical technology for remote sensing are discussed in reviews and reports of recent experimental investigations. Topics examined include industrial applications, laser diagnostics for combustion research, laser remote sensing for ranging and altimetry, and imaging systems for terrestrial remote sensing from space. Consideration is given to LIF in forensic diagnostics, time-resolved laser-induced-breakdown spectrometry for rapid analysis of alloys, CARS in practical combustion environments, airborne inertial surveying using laser tracking and profiling techniques, earth-resources instrumentation for the EOS polar platform of the Space Station, and the SAR for EOS.

  13. Race to the Top. Ohio. State-Reported APR: Year One

    ERIC Educational Resources Information Center

    US Department of Education, 2012

    2012-01-01

    This paper describes Ohio's progress in implementing a comprehensive and coherent approach to education reform from the time of application through June 30, 2011. The sections presented in this report highlight key accomplishments made by Ohio to implement a comprehensive and coherent approach to education reform over the reporting period in the…

  14. Race to the Top. Hawaii. State-Reported APR: Year One

    ERIC Educational Resources Information Center

    US Department of Education, 2012

    2012-01-01

    This paper describes Hawaii's progress in implementing a comprehensive and coherent approach to education reform from the time of application through June 30, 2011. In particular, it highlights key accomplishments over the reporting period in the four reform areas: standards and assessments, data systems to support instruction, great teachers and…

  15. AFRRI reports, second quarter 1992. Rept. for Apr-Jul 92

    SciTech Connect

    Not Available

    1992-07-01

    This report includes the following topics: Short and long courses of ofloxacin therapy of Klebsiella pneumoniae sepsis following irradiation, Possible 'accelerated striatal aging' induced by 56Fe heavy-particle irradiation: Implications for manned space flights, Modulation of mortality by tissue trauma and sepsis in mice after radiation injury, Cytokine therapy in canine and primate models of radiation-induced marrow aplasia, Comparison of behavioral and radioprotective effects of WR-2721 and WR-3689, Energy transfer mechanisms in DNA: Relationship to energy deposition in sub-microscopic volumes, Role of interleukin 6 (IL-6) in protection from lethal irradiation and in endocrine responses to IL-1 and tumor necrosis factor, Effects on enhancing hemopoietic reconstitution and increasing survival following exposure to ionizing radiation, and Radioprotection of hematopoietic tissues in mice by lipoic acid.

  16. Infrared readout electronics; Proceedings of the Meeting, Orlando, FL, Apr. 21, 22, 1992

    NASA Technical Reports Server (NTRS)

    Fossum, Eric R. (Editor)

    1992-01-01

    The present volume on IR readout electronics discusses cryogenic readout using silicon devices, cryogenic readout using III-V and LTS devices, multiplexers for higher temperatures, and focal-plane signal processing electronics. Attention is given to the optimization of cryogenic CMOS processes for sub-10-K applications, cryogenic measurements of aerojet GaAs n-JFETs, inP-based heterostructure device technology for ultracold readout applications, and a three-terminal semiconductor-superconductor transimpedance amplifier. Topics addressed include unfulfilled needs in IR astronomy focal-plane readout electronics, IR readout integrated circuit technology for tactical missile systems, and radiation-hardened 10-bit A/D for FPA signal processing. Also discussed are the implementation of a noise reduction circuit for spaceflight IR spectrometers, a real-time processor for staring receivers, and a fiber-optic link design for INMOS transputers.

  17. Investigation of laser-induced retinal damage. Annual report, 1 Apr 91-31 Mar 92

    SciTech Connect

    Glickman, R.D.; Lam, K.W.

    1992-04-22

    Laser-induced, photooxidative damage in ocular tissue was studied with a quantitative assay using high performance liquid chromatography (HPLC) to separate oxidized and reduced ascorbic acid in exposed tissue components. We demonstrated that ascorbic acid, incubated with whole, bovine retinal pigment epithelial (RPE) cells, was oxidized when the reaction mixture was exposed to the output of an argon-ion continuous wave laser The amount of ascorbic acid oxidized was proportional to the irradiance of the sample, and the reaction was wavelength-dependent, with short-wavelength visible light more effective than long-wavelengths in driving the, reaction. The photosensitizing activity was associated with the RPE melanin pigment granules, and was not lost after disrupting or heating the RPE cells. Because melanin was known to form free radicals when illuminated, we hypothesized that ascorbic acid detoxified the light-activated melanin free radicals while being itself oxidized in process. If the supply of reduced ascorbic acid were exhausted, however, the activated melanin could have been the source of tissue-damaging radicals. This model was consistent with a photochemical damage mechanism involving light-activated melanin.

  18. Space Congress, 27th, Cocoa Beach, FL, Apr. 24-27, 1990, Proceedings

    SciTech Connect

    Not Available

    1990-01-01

    The present symposium on aeronautics and space encompasses DOD research and development, science payloads, small microgravity carriers, the Space Station, technology payloads and robotics, commercial initiatives, STS derivatives, space exploration, and DOD space operations. Specific issues addressed include the use of AI to meet space requirements, the Astronauts Laboratory Smart Structures/Skins Program, the Advanced Liquid Feed Experiment, an overview of the Spacelab program, the Autonomous Microgravity Industrial Carrier Initiative, and the Space Station requirements and transportation options for a lunar outpost. Also addressed are a sensor-data display for telerobotic systems, the Pegasus and Taurus launch vehicles, evolutionary transportation concepts, the upgrade of the Space Shuttle avionics, space education, orbiting security sentinels, and technologies for improving launch-vehicle responsiveness.

  19. Pathfinder, v6 n2, Mar/Apr 2008. Strengthening NGA Partnerships Around the World

    DTIC Science & Technology

    2008-04-01

    earthquake measuring 8.0 on the Richter scale destroyed much of Ica , a town in southern Peru . NGA provided Nicaragua with commercial imagery iden...Caribbean. Other products mitigated fires in Mexico, floods in Panama, and earthquakes in Peru . Requests originated from both U.S. representatives in the...as well as NGA’s regional offices in Guatemala, which covers Central America and the Caribbean, and in Peru , which also covers Bolivia and Ecuador

  20. 78 FR 2684 - Notice of Proposed Information Collection for Public Comment: Annual Progress Report (APR) for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-14

    ... appropriate automated collection techniques or other forms of information technology; e.g., permitting... (SRO) Program. Estimation of the total number of hours needed to prepare the information collection...,250 responses x 1,680 minutes = 91,000 hours per annum) + AHAR with Automated Software Report (425...

  1. Space Electrochemical Research and Technology Conference, 2nd, Cleveland, OH, Apr. 11-13, 1989, Proceedings

    NASA Astrophysics Data System (ADS)

    O'Donnell, Patricia M.

    1990-02-01

    Attention is given to topics of advanced concepts, hydrogen-oxygen fuel cells and electrolyzers, nickel electrodes, and advanced rechargeable batteries. Papers are presented on human exploration mission studies, advanced rechargeable sodium batteries with novel cathodes, advanced double-layer capacitors, recent advances in solid-polymer electrolyte fuel cell technology with low platinum loading electrodes, electrocatalysts for oxygen electrodes in fuel cells and water electrolyzers for space applications, and the corrosion testing of candidates for the alkaline fuel cell cathode. Other papers are on a structural comparison of nickel electodes and precursor phases, the application of electrochemical impedance spectroscopy for characterizing the degradation of Ni(OH)2/NiOOH electrodes, advances in lightweight nickel electrode technology, multimission nickel-hydrogen battery cell for the 1990s, a sodium-sulfur battery flight experiment definition study, and advances in ambient-temperature secondary lithium cells.

  2. Smart battery controller for lithium/sulfur dioxide batteries. Technical report, Jan 89-Apr 91

    SciTech Connect

    Atwater, T.; Bard, A.; Testa, B.; Shader, W.

    1992-08-01

    Each year, the U.S. Army purchases millions of lithium sulfur dioxide batteries for use in portable electronics equipment. Because of their superior rate capability and service life over a wide variety of conditions, lithium batteries are the power source of choice for military equipment. There is no convenient method of determining the available energy remaining in partially used lithium batteries; hence, users do not take full advantage of all the available battery energy. Currently, users replace batteries before each mission, which leads to premature disposal, and results in the waste of millions of dollars in battery energy every year. Another problem of the lithium battery is that it is necessary to ensure complete discharge of the cells when the useful life of the battery has been expended, or when a hazardous condition exists; a hazardous condition may result in one or more of the cells venting. The Electronics Technology and Devices Laboratory has developed a working prototype of a smart battery controller (SBC) that addresses these problems.

  3. Visual information processing II; Proceedings of the Meeting, Orlando, FL, Apr. 14-16, 1993

    NASA Technical Reports Server (NTRS)

    Huck, Friedrich O. (Editor); Juday, Richard D. (Editor)

    1993-01-01

    Various papers on visual information processing are presented. Individual topics addressed include: aliasing as noise, satellite image processing using a hammering neural network, edge-detetion method using visual perception, adaptive vector median filters, design of a reading test for low-vision image warping, spatial transformation architectures, automatic image-enhancement method, redundancy reduction in image coding, lossless gray-scale image compression by predictive GDF, information efficiency in visual communication, optimizing JPEG quantization matrices for different applications, use of forward error correction to maintain image fidelity, effect of peanoscanning on image compression. Also discussed are: computer vision for autonomous robotics in space, optical processor for zero-crossing edge detection, fractal-based image edge detection, simulation of the neon spreading effect by bandpass filtering, wavelet transform (WT) on parallel SIMD architectures, nonseparable 2D wavelet image representation, adaptive image halftoning based on WT, wavelet analysis of global warming, use of the WT for signal detection, perfect reconstruction two-channel rational filter banks, N-wavelet coding for pattern classification, simulation of image of natural objects, number-theoretic coding for iconic systems.

  4. Investigation of electron attachment in polyatomic molecules. Final report 1 Apr 77-31 Mar 80

    SciTech Connect

    Dowell, J.T.

    1980-05-30

    Electron attachment to polyatomic molecules was studied using molecular beams of variable temperature crossed with an electron of high energy resolution. Species investigated include sulfur hexafluoride, molybdenum hexafluoride, and tungsten oxide polymers. New results were obtained in sulfur hexafluoride demonstrating importance of internal energy for the dissociative attachment in molybdenum hexafluoride. Tungsten oxide vapor exhibits both monomer and dimer negative ion formation near zero energy, apparently from dissociative attachment to the trimer.

  5. Project CHECO Southeast Asia Report. Airlift to Besieged Areas, 7 Apr-31 Aug 72

    DTIC Science & Technology

    1973-12-07

    operating elements, the commander of the 374th TAW stated that mass formation airdrop demonstrations (e.g., BRASS m STRIKE and BRAVE SHIELD given to joint...navigator who used the data to make corrections on his own CARP computations. (# In another measure instituted to improve the overall results, the...The proposal, in the form of a Combat Required I Operational Capability ( CROC ) 26-72, called for the VNAF C-47 and C-123 aircraft to be replaced by two

  6. Weaving the astronomy web. Proceedings. Conference, Strasbourg (France), 6 - 7 Apr 1995.

    NASA Astrophysics Data System (ADS)

    The following topics were dealt with: the Electronic Astrophysical Journal Letters project; astronomical information infrastructure; electronic publication; data distribution; dynamic form generation and image map techniques; on-line image archive; library services; Astrophysics Data System; solar information; HST and ESO archives; digital sky surveys; WWW interfaces and access; databases and astronomical resources; astronomical catalogues; multimedia astronomy using CD-ROMs; and observing applications.

  7. Remote sensing; Proceedings of the Meeting, Orlando, FL, Apr. 3, 4, 1986

    NASA Technical Reports Server (NTRS)

    Menzies, Robert T. (Editor)

    1986-01-01

    Advances in optical technology for remote sensing are discussed in reviews and reports of recent experimental investigations. Topics examined include industrial applications, laser diagnostics for combustion research, laser remote sensing for ranging and altimetry, and imaging systems for terrestrial remote sensing from space. Consideration is given to LIF in forensic diagnostics, time-resolved laser-induced-breakdown spectrometry for rapid analysis of alloys, CARS in practical combustion environments, airborne inertial surveying using laser tracking and profiling techniques, earth-resources instrumentation for the EOS polar platform of the Space Station, and the SAR for EOS.

  8. Williamson Home, Ipswich, Mass. solar-energy-system performance evaluation, Nov. 1981 - Apr. 1982

    NASA Astrophysics Data System (ADS)

    Cramer, M.

    1982-06-01

    Data on solar water and space heating systems are given. The Williamson Home in Massachusetts is a single family residence whose active-solar-energy system is designed to supply 47% of the space heating and 91% of the hot water. The system is equipped with 339 square feet of flat plate collectors, a 240-cubic-foot rock bin for storage, a propane-gas furnace and a 100-gallon propane gas hot water tank for auxiliary heating. Monthly performance data are tabulated for the overall system and for the collector, hot water, and space heating subsystems. Also tabulated are solar coefficients of performance, solar operating energy, energy savings, and weather conditions. Also given is a graph of collector array efficiency versus the difference between the inlet water and ambient temperatures divided by insolation. System operation is illustrated by graphs of typical insolation data and outside ambient and indoor temperatures, collector operating periods and inlet/outlet temperatures, and typical storage and distribution temperatures versus time for a typical day. The system operating sequence and solar energy utilization and losses are also graphed.

  9. Méningite après rachianesthésie

    PubMed Central

    Mouchrif, Issam; Berdaii, Adnane; Labib, Ismail; Harrandou, Moustapha

    2016-01-01

    Les méningites sont des complications rares mais graves des anesthésies péridurales et des rachianesthésies. Les méningites bactériennes sont essentiellement dues à des cocci à Gram positif, ce qui sous-entend une contamination exogène pouvant être le témoin d'une faute d'asepsie. L’évolution est le plus souvent favorable sous traitement, mais au prix d'un accroissement des dépenses de santé et parfois d'importantes séquelles neurologiques. Nous présentons un cas de méningite bactérienne au décours d'une rachianesthésie effectué pour césarienne. PMID:27642477

  10. GOES Animation of the Tornadoes from Apr. 27-28, 2014

    NASA Image and Video Library

    This animation of NOAA's GOES-East satellite data shows the development and movement of the weather system that spawned tornadoes affecting seven central and southern U.S. states on April 27-28, 20...

  11. Hydrogen-fueled scramjet investigation. Final report, Feb 87-Apr 90

    SciTech Connect

    Peschke, W.T.; Barber, T.J.; Chiappetta, L.; Anderson, T.J.; Eckerle, W.J.

    1991-02-01

    This report documents an experimental and analytical study of the supersonic mixing and combustion processes associated with a free-shear layer. A specific objective comprised quantifying the effects on the mixing and combustion processes of pressure gradients associated with the production of shock waves in the flowfield. An experiment was conducted in a generic supersonic combustion configuration that incorporated the essential characteristics of scramjet combustors currently being considered for flight application. The objective of the analytical effort was to evaluate mixing and combustion models in state-of-the-art computational fluid dynamics (CFD) codes. The experiments provided accurate data used to formulate code input conditions and to evaluate codes that were formulated for application in current high-speed propulsion design activities. Species concentration, total and static temperature, and pitot pressure profiles were measured in a shear layer experiment in which gaseous hydrogen was injected tangentially into a Mach 3 (nominal) vitiated air stream. In this experiment, hydrogen was injected adjacent to the upperwall of the test section. A nonintrusive optical diagnostic technique was used in conjunction with intrusive probing to define the flowfield initial conditions and to characterize the detailed features of the flowfield subsequent to hydrogen injection and combustion.

  12. Applications of artificial intelligence IX; Proceedings of the Meeting, Orlando, FL, Apr. 2-4, 1991

    SciTech Connect

    Trivedi, M.M.

    1991-01-01

    The present conference discusses expert systems, object-detection techniques, planning and scheduling, image-analysis methods, knowledge-based systems, robot vision systems, AI-based diagnosis methods, design environment and tools for intelligent robots, and mobile robots. Also discussed are intelligent robot architectures, machine/computer vision applications, knowledge-acquisition and knowledge-based system verification, three-dimensional robot vision, image modeling, synthesis, and evaluation, applications of neural networks, hardware architectures for AI, planning robotic tasks, the representation and machine comprehension of natural language, and 3D textured vision systems.

  13. Solvent-emissions reduction study at Newark AFB, Ohio. Final report, Aug 88-Apr 89

    SciTech Connect

    Ayer, J.; Wolbach, C.D.

    1990-05-01

    The objective of this effort was to collect baseline Freon emissions data, and subsequently recommend potential emission control alternatives to minimize Freon emissions that result from routine maintenance and repair operations conducted at Newark AFB, Ohio. Newark AFB, Ohio, uses a number of solvents to clean and maintain electronic guidance devices. The solvent most often used in this application is 1,1,2-trichloro-1,2,2-trifluoroethane, a solvent commonly known by the DuPont Company trademark Freon 113TM (hereafter referred to as Freon). Newark AFB purchases large quantities of Freon (nearly 600,000 pounds annually), and in previous years, lost nearly all of it (555,000 pounds) as unrecovered Freon vapor. Freon is one of a general class of chemicals known as chlorofluorocarbons (CFCs). Scientific evidence strongly suggests that CFC emissions are responsible for the depletion of the protective ozone layer surrounding the earth's atmosphere. For this reason, the U.S. air Force must reduce and eventually eliminate CFC emissions from Air Force facilities. Several steps have been taken to reduce the quantity of Freon emitted from the more than 100 emission point sources at Newark AFB. For example, the recovery of solvent vapors emitted from more than half of the point sources at the facility is achieved with limited success by the use of two carbon adsorption (CA) systems.

  14. The Lower Solar Atmosphere During the WHI Campaign (20 Apr-16 May 2008)

    NASA Technical Reports Server (NTRS)

    Sterling, Alphonse

    2009-01-01

    The Whole Heliospheric Interval (WHI) period of 20 March - 16 April had a "quiet side" of the Sun, and an "active side," with three ARs. At least two of the ARs produced CMEs, but there were several events that may have been "confined eruptions" from these regions too. Examining the magnetic environment of the erupting regions gives insight into the onset and dynamics of the eruptions. Several of the CMEs can be traced back to likely disk sources, but several unmatched cases still remain. More work is needed to sort through these points.

  15. Subregional variability in Missouri tornado statistics. Technical report Apr 77-Jun 79

    SciTech Connect

    Jamison, S.W.; Darkow, G.L.

    1981-11-01

    The reality of subregional variability in tornado occurrence density as evidenced in the county to county variability in Missouri is examined. Reported tornadoes for the period from 1916 through 1975 were used. Demographic and geographic factors known to impact on tornado reporting efficiencies and accuracies are related to county tornado report densities by step-wise multiple linear regression techniques. The analysis suggests that over 75 percent of the county to county apparent variability in reported tornado densities in Missouri is explainable in terms of variability in population density, other related demographic variables and regional scale geographic factors.

  16. Applications of artificial intelligence III; Proceedings of the Meeting, Orlando, FL, Apr. 1-3, 1986

    SciTech Connect

    Gilmore, J.F.

    1986-01-01

    Papers are presented on expert systems for such functions as model management, the labeling segment in FLIR imagery, and on-board fault monitoring and diagnosis; procedures for analyzing and interpreting images; and knowledge-based systems for planning, ship identification, fault-identification systems, design issues, interpretation of signal images, and electronic circuit-diagram interpretation. Topics discussed include image procesing, heuristic systems, and knowledge presentation. Consideration is given to pattern recognition, robotics, and a number of artificial intelligence applications.

  17. Visual information processing; Proceedings of the Meeting, Orlando, FL, Apr. 20-22, 1992

    NASA Technical Reports Server (NTRS)

    Huck, Friedrich O. (Editor); Juday, Richard D. (Editor)

    1992-01-01

    Topics discussed in these proceedings include nonlinear processing and communications; feature extraction and recognition; image gathering, interpolation, and restoration; image coding; and wavelet transform. Papers are presented on noise reduction for signals from nonlinear systems; driving nonlinear systems with chaotic signals; edge detection and image segmentation of space scenes using fractal analyses; a vision system for telerobotic operation; a fidelity analysis of image gathering, interpolation, and restoration; restoration of images degraded by motion; and information, entropy, and fidelity in visual communication. Attention is also given to image coding methods and their assessment, hybrid JPEG/recursive block coding of images, modified wavelets that accommodate causality, modified wavelet transform for unbiased frequency representation, and continuous wavelet transform of one-dimensional signals by Fourier filtering.

  18. Grazing incidence optics; Proceedings of the Meeting, Orlando, FL, Apr. 3, 4, 1986

    NASA Technical Reports Server (NTRS)

    Osantowski, John F. (Editor); Van Speybroeck, Leon (Editor)

    1986-01-01

    Papers are presented on the diffraction-limited performance of grazing incidence optical systems; transverse ray aberrations of Wolter type 1 telescopes; hybrid X-ray telescope systems; surface characterization of grazing incidence optics in the extreme UV and X-ray regions; and the surface roughness properties of synchrotron radiation optics. Topics discussed include the simulation of free-abrasive grinding of grazing incidence mirrors with vertical-honing and flexible blades; mirrors for the Extreme Ultraviolet Explorer; the design and development of conical X-ray imaging mirrors; thermal loading considerations for synchrotron radiation mirrors; and grazing incidence optics for synchrotron radiation insertion-device beams. Consideration is given to the interpretation of glancing incidence scattering measurements; damage processes in short wavelength coated FEL optics; the replication of grain incidence optics; and the assembly and alignment of the Technology Mirror Assembly.

  19. Space Congress, 28th, Cocoa Beach, FL, Apr. 23-26, 1991, Proceedings

    NASA Astrophysics Data System (ADS)

    1991-11-01

    The present conference on aerospace developments and issues encompasses interstellar and space-exploration initiatives, commercial space development, science payloads, space shuttle derivatives, space education, and Space Station activities. Specific issues addressed include magnetic shielding for interplanetary spacecraft, a launch-site comparison between the earth, moon, and Mars, the Spacehab approach, commercial infrastructure participation in the Space Station Freedom (SSF), the science uses of tethered satellites in low planetary orbits, and enabling life-sciences research on the SSF. Also addressed are simulations of shuttle and derivative-vehicle processing, daily operations that support the Global Positioning System, the utilization of common pressured modules on the SSF, the development of ground- and space-based laser systems, the crisis in human capital, and the automated servicing of scientific payloads aboard orbiting laboratories.

  20. Space Congress, 27th, Cocoa Beach, FL, Apr. 24-27, 1990, Proceedings

    NASA Technical Reports Server (NTRS)

    1990-01-01

    The present symposium on aeronautics and space encompasses DOD research and development, science payloads, small microgravity carriers, the Space Station, technology payloads and robotics, commercial initiatives, STS derivatives, space exploration, and DOD space operations. Specific issues addressed include the use of AI to meet space requirements, the Astronauts Laboratory Smart Structures/Skins Program, the Advanced Liquid Feed Experiment, an overview of the Spacelab program, the Autonomous Microgravity Industrial Carrier Initiative, and the Space Station requirements and transportation options for a lunar outpost. Also addressed are a sensor-data display for telerobotic systems, the Pegasus and Taurus launch vehicles, evolutionary transportation concepts, the upgrade of the Space Shuttle avionics, space education, orbiting security sentinels, and technologies for improving launch-vehicle responsiveness.

  1. Space Congress, 29th, Cocoa Beach, FL, Apr. 21-24, 1992, Proceedings

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The present volume on the quest for new frontiers in space discusses weather impacts on space operations, planning for the performance of future space bases, a new guidance and control unit for the Titan IV vehicle, and nondestructive evaluation of Shuttle Columbia tiles. Attention is given to Space Shuttle payload accommodations and trends in customer demands, a generic propellants transfer unit, making space part of general education, space station on-orbit solar array loads during assembly, and dimensional stability of the attitude reference assembly on SSF. Topics addressed include National Launch System payload accommodations and launch operations, the integrated factory/launch site processing concept, Pioneer 10 interstellar studies, and the role of advanced nuclear propulsion systems in precursor interstellar missions. Also discussed are legal challenges in realizing interstellar initiatives, Mars transportation system synthesis, and NASA's commercial space program.

  2. Space Congress, 29th, Cocoa Beach, FL, Apr. 21-24, 1992, Proceedings

    NASA Astrophysics Data System (ADS)

    The present volume on the quest for new frontiers in space discusses weather impacts on space operations, planning for the performance of future space bases, a new guidance and control unit for the Titan IV vehicle, and nondestructive evaluation of Shuttle Columbia tiles. Attention is given to Space Shuttle payload accommodations and trends in customer demands, a generic propellants transfer unit, making space part of general education, space station on-orbit solar array loads during assembly, and dimensional stability of the attitude reference assembly on SSF. Topics addressed include National Launch System payload accommodations and launch operations, the integrated factory/launch site processing concept, Pioneer 10 interstellar studies, and the role of advanced nuclear propulsion systems in precursor interstellar missions. Also discussed are legal challenges in realizing interstellar initiatives, Mars transportation system synthesis, and NASA's commercial space program. (For individual items see A93-25277 to A93-25313)

  3. Race to the Top. Delaware. State-Reported APR: Year One

    ERIC Educational Resources Information Center

    US Department of Education, 2012

    2012-01-01

    This paper describes Delaware's progress in implementing a comprehensive and coherent approach to education reform from the time of application through June 30, 2011. In particular, it highlights key accomplishments over the reporting period in the four reform areas: standards and assessments, data systems to support instruction, great teachers…

  4. Atmospheric propagation and remote sensing; Proceedings of the Meeting, Orlando, FL, Apr. 21-23, 1992

    SciTech Connect

    Kohnle, A.; Miller, W.B.

    1992-01-01

    Topics addressed include modeling aerosol extinction in a coastal environment, a specific marine boundary layer aerosol model, light scattering of fractal aerosol aggregates using a T-matrix method, a lidar inversion technique using total attenuation and the lidar system constant, a comparison of two retrieval methods for ground reflectance, a two-wavelength lidar inversion technique, and conceptual design of a spaceborne radar for rain and cloud sensing. Also discussed are an energy balance model for imagery and electromagnetic propagation, short-exposure imaging of nonisoplanatic objects through turbulence, atmospheric modeling with an intent of training a neural net wavefront sensor, effect of random layers on atmospheric propagation, atmospheric effects on laser radar performance at 2 microns, the adjacency-blurring effect of scenes modeled by the radiosity method, atmospheric transmittance measurements of CO2 and near-IR laser radiation over 8.6 km, and a comparison of turbulence modulation transfer function (MTF) and aerosol MTF.

  5. International Instrumentation Symposium, 38th, Las Vegas, NV, Apr. 26-30, 1992, Proceedings

    SciTech Connect

    Not Available

    1992-01-01

    The present volume on aerospace instrumentation discusses computer applications, blast and shock, implementation of the Clean Air Act amendments, and thermal systems. Attention is given to measurement uncertainty/flow measurement, data acquisition and processing, force/acceleration/motion measurements, and hypersonics/reentry vehicle systems. Topics addressed include wind tunnels, real time systems, and pressure effects. Also discussed are a distributed data and control system for space simulation and thermal testing a stepwise shockwave velocity determinator, computer tracking and decision making, the use of silicon diodes for detecting the liquid-vapor interface in hydrogen, and practical methods for analysis of uncertainty propagation.

  6. Energy-conserving coating - pigment research. Final report, Sep 88-Apr 91

    SciTech Connect

    Novinson, T.

    1991-05-01

    This report documents research into novel experimental paints made from color-reversible pigments. These pigments are of two types: Photochromic and thermochromic. The first group changes color on exposure to light, and the second changes color when subjected to a change in temperature. If successfully incorporated into a coating and applied to walls and roofs, these pigments could reduce heating and cooling costs by presenting a more absorbent color in the winter and a more reflective color in the summer.

  7. Novel optoelectronic devices; Proceedings of the Meeting, The Hague, Netherlands, Mar. 31-Apr. 2, 1987

    NASA Technical Reports Server (NTRS)

    Adams, Michael J. (Editor)

    1987-01-01

    The present conference on novel optoelectronics discusses topics in the state-of-the-art in this field in the Netherlands, quantum wells, integrated optics, nonlinear optical devices and fiber-optic-based devices, ultrafast optics, and nonlinear optics and optical bistability. Attention is given to the production of fiber-optics for telecommunications by means of PCVD, lifetime broadening in quantum wells, nonlinear multiple quantum well waveguide devices, tunable single-wavelength lasers, an Si integrated waveguiding polarimeter, and an electrooptic light modulator using long-range surface plasmons. Also discussed are backward-wave couplers and reflectors, a wavelength-selective all-fiber switching matrix, the impact of ultrafast optics in high-speed electronics, the physics of low energy optical switching, and all-optical logical elements for optical processing.

  8. Applications of artificial intelligence VIII; Proceedings of the Meeting, Orlando, FL, Apr. 17-19, 1990

    SciTech Connect

    Trivedi, M.M.

    1990-01-01

    The present conference on applications of artificial intelligence (AI) encompasses computer vision, knowledge acquisition and representation, model-based vision, neural networks, robot planning, knowledge-based systems, path planning, image analysis, AI in aerospace systems, and semiconductor manufacturing systems. Specific issues addressed include object detection using scale space, nonmonotonic scene interpretation, 3D object reconstruction from multiple stereo views, recognition via alignment using aspect models, target detection in a neural-network environment, the optimization of precedence-constraint robot assembly sequences, and free-space representations for robot-path planning. Also addressed are an edge-detection method, an approach to elemental task learning, issues in building intelligent grasping systems, an oral task-oriented dialogue for air-traffic controller training, and the experimental optimization of the neuronlike network applied for the processing of moving images.

  9. Data structures and target classification; Proceedings of the Meeting, Orlando, FL, Apr. 1, 2, 1991

    NASA Astrophysics Data System (ADS)

    Libby, Vibeke

    1991-08-01

    The present conference discusses topics in multisensor fusion and signal processing, data structures in distributed environments, computational methods and architectures, and automatic target recognition. Attention is given to the adaptive selection of sensors, multisensor imagery fusion based on target motion, multisensor imaging technology for airborne surveillance, optimal topology communications networks, scanning strategies for target detection, VLSI fuzzy-logic controller design, an optical pattern recognizer, radar-based target recognition techniques, and algorithms for radar clutter statistical classification.

  10. Time-dependent gravity in southern California, May 1974 - Apr 1979

    NASA Technical Reports Server (NTRS)

    Whitcomb, J. H.; Franzen, W. O.; Given, J. W.; Pechman, J. C.; Ruff, L. J.

    1979-01-01

    Gravity measurements were coordinated with the long baseline three dimensional geodetic measurements of the Astronomical Radio Interferometric Earth Surveying project which used radio interferometry with extra-galactic radio sources. Gravity data from 28 of the stations had a single reading standard deviation of 11 microgal which gives a relative single determination between stations a standard deviation of 16 microgal. The largest gravity variation observed, 80 microgal, correlated with nearby waterwell variations and with smoothed rainfall. Smoothed rainfall data appeared to be a good indicator of the qualitative response of gravity to changing groundwater levels at other suprasediment stations, but frequent measurement of gravity at a station was essential until the quantitative calibration of the station's response to groundwater variations was accomplished.

  11. 78 FR 37531 - Agency Information Collection Activities; Comment Request; Annual Performance Reporting (APR...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-21

    ...); Advanced Rehabilitation Research Training Projects (ARRTs); Model Systems (including spinal cord injury, traumatic brain injury, and burn centers); Disability and Rehabilitation Research Projects (DRRPs...

  12. Race to the Top. Maryland. State-Reported APR: Year One

    ERIC Educational Resources Information Center

    US Department of Education, 2012

    2012-01-01

    This paper describes Maryland's progress in implementing a comprehensive and coherent approach to education reform from the time of application through June 30, 2011. In particular, this report highlights key accomplishments over the reporting period in the four reform areas: standards and assessments, data systems to support instruction, great…

  13. Race to the Top. Tennessee. State-Reported APR: Year One

    ERIC Educational Resources Information Center

    US Department of Education, 2012

    2012-01-01

    This paper describes Tennessee's progress in implementing a comprehensive and coherent approach to education reform from the time of application through June 30, 2011. In particular, this report highlights key accomplishments over the reporting period in the four reform areas: standards and assessments, data systems to support instruction, great…

  14. Visual information processing II; Proceedings of the Meeting, Orlando, FL, Apr. 14-16, 1993

    NASA Technical Reports Server (NTRS)

    Huck, Friedrich O. (Editor); Juday, Richard D. (Editor)

    1993-01-01

    Various papers on visual information processing are presented. Individual topics addressed include: aliasing as noise, satellite image processing using a hammering neural network, edge-detetion method using visual perception, adaptive vector median filters, design of a reading test for low-vision image warping, spatial transformation architectures, automatic image-enhancement method, redundancy reduction in image coding, lossless gray-scale image compression by predictive GDF, information efficiency in visual communication, optimizing JPEG quantization matrices for different applications, use of forward error correction to maintain image fidelity, effect of peanoscanning on image compression. Also discussed are: computer vision for autonomous robotics in space, optical processor for zero-crossing edge detection, fractal-based image edge detection, simulation of the neon spreading effect by bandpass filtering, wavelet transform (WT) on parallel SIMD architectures, nonseparable 2D wavelet image representation, adaptive image halftoning based on WT, wavelet analysis of global warming, use of the WT for signal detection, perfect reconstruction two-channel rational filter banks, N-wavelet coding for pattern classification, simulation of image of natural objects, number-theoretic coding for iconic systems.

  15. ONRASIA Scientific Information Bulletin. Volume 17, Number 2, Apr-Jun 1992

    DTIC Science & Technology

    1992-06-01

    points he made were (1) direct practices." Drs. Yasunori Baba and such as "DNA" or " lasers " reflected investment is much greater than imag- Ikujiro Nonaka...high technological interest. inversion is hard to achieve. 45 SIB 17 (2) 92 (4) Focused ion beam (FIB) etching for micromachining and FIB- S. Ashok...and Learning Functions 7. Basic Study on Free Electron Laser Oscillation 3. Biological Energy Conversion 8. I ligh-Field Pulsed Superconducting Magnet

  16. Space Congress, 25th, Cocoa Beach, FL, Apr. 26-29, 1988, Proceedings

    SciTech Connect

    Not Available

    1988-01-01

    Papers are presented dealing with commercial aspects of space, space business, robotics, space station technologies, artificial intelligence applications in space, lunar and Mars exploration concepts, launch vehicles, and systems automation. Topics covered include ground processing of experiments conducted in space, the development of a commercial expendable launch vehicle industry, a small LEO satellite bus, epitaxial thin film growth in space, development of space enterprise, negotiating governmental contracts, robots in Shuttle hardware, telerobotic Space Station applications, simulation of an articulated transporter/manipulator system, welding the Space Station common module prototype, modeling the environment of the Man Tended Free Flyer, and Space Station rapid sample return. Ground operations support by AI, expert system prototype developments, Mars mission profile options and opportunities, launch vehicle operations analyses, space launch systems resiliency, model-based reasoning for knowledge-based software project management, technology advances for Space Shuttle processing, real-time fault management for large-scale systems, information systems for Shuttle processing, orbiter maneuvering vehicle support to the Space Station, and hydrogen-air-steam combustion regimes in large volumes are also discussed.

  17. 15 CFR 781.2 - Purposes of the Additional Protocol and APR.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... to additional information about civil nuclear and nuclear-related items, materials, and activities and with physical access to reportable locations where nuclear facilities, materials, or ores are located (to ensure the absence of undeclared nuclear material and activities) and to other reportable...

  18. 15 CFR 781.2 - Purposes of the Additional Protocol and APR.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... to additional information about civil nuclear and nuclear-related items, materials, and activities and with physical access to reportable locations where nuclear facilities, materials, or ores are located (to ensure the absence of undeclared nuclear material and activities) and to other reportable...

  19. Les Cicatrices Retractiles Post-Brulures Du Membre Inferieur Chez L’Enfant

    PubMed Central

    Sankale, A.A.; Manyacka Ma Nyemb, P.; Coulibaly, N.F.; Ndiaye, A.; Ndoye, M.

    2010-01-01

    Summary Il s'agit d'une étude faisant ressortir les aspects épidémiologiques, cliniques et thérapeutiques des séquelles de brûlures du membre inférieur chez l'enfant, à propos de 42 cas colligés au service de chirurgie infantile de l'Hôpital Aristide Le Dantec (Sénégal). L'âge moyen retrouvé est de 5 ans et 3 mois, et le sex-ratio garçons/filles de 1,8/1. La brûlure thermique est causée par une flamme dans 33% des cas, par un liquide chaud dans 21% des cas, et par des braises dans 21% des cas. Les cicatrices rétractiles intéressent le genou et le creux poplité dans 47% des cas et le pied dans 45% des cas. Elles sont bilatérales dans 21% des cas, et concernent une autre localisation associée dans 21% des cas. Quant aux brides, 21% ont bénéficié d'une chirurgie, avec un délai moyen de 3 ans et 2 mois après la brûlure. Cette procédure chirurgicale consiste en une plastie en Z dans 91% des cas, à laquelle est associée une greffe de peau dans 54% des cas. Une rééducation fonctionnelle est pratiquée chez 54% des opérés. Parallèlement aux données de la littérature, nos résultats montrent que l'optimisation de la prise en charge passe par une meilleure prévention des accidents domestiques et une bonne codification thérapeutique. PMID:21991202

  20. Oncoplastie avec conservation mammaire dans le traitement du cancer du sein: à propos de 16 cas

    PubMed Central

    Bouzoubaa, Wail; Laadioui, Meryam; Jayi, Sofia; Alaoui, Fatime Zahra Fdili; Bouguern, Hakima; Chaara, Hikmat; Melhouf, Moulay Abdelilah

    2015-01-01

    Le cancer du sein est actuellement le cancer le plus fréquent chez la femme, et pose un véritable problème diagnostique et thérapeutique. Le dépistage des lésions à un stade de plus en plus précoce, a permis une extension des indications du traitement conservateur radiochirurgical, qui était initialement limitées aux tumeurs de moins de 3 cm, unifocales, non inflammatoires. Par ailleurs, l'utilisation de traitements préopératoires permet d’étendre les indications du traitement conservateur à des tumeurs plus volumineuses. Parallèlement à cette extension des indications de conservation mammaire, on a observé le développement de nouvelles approches thérapeutiques notamment la chirurgie oncoplastique, technique du ganglion sentinelle et chirurgie stéréotaxique, dont les résultats initiaux sont très encouragent. A travers cette étude réalisée dans le service de gynécologie et obstétrique II du CHU HASSAN II de FES au MAROC, après l'analyse rétrospective de 16 patientes traitées par traitement conservateur et oncoplastie, nous avons voulus montrer notre aptitude a réalisé ses techniques chirurgicales et a bien prendre en charge ces patientes, mais aussi évaluer ces techniques en termes de résultat carcinologique et de résultat esthétique, aussi en terme de survie globale, survie sans métastase et en termes de récidive locale entre les plasties mammaires et les traitements usuels: mastectomie et traitement conservateur classique. PMID:26430477

  1. Anesthésie pour prothése totale de la hanche: à propos de 50 cas

    PubMed Central

    Serghini, Issam; Qamouss, Youssef; Zoubir, Mohamed; Lalaoui, Jaafar Salim; Koulali, Idrissi Khalid; Boughalem, Mohamed

    2015-01-01

    La chirurgie de la prothèse totale de la hanche (PTH) est une chirurgie fonctionnelle qui consiste en un remplacement d'une articulation endommagée afin d'améliorer la qualité de vie du patient. L'anesthésie pour PTH exige une préparation rigoureuse à l'intervention, la consultation d'anesthésie sera donc la clef de cette réussite. Nous avons réalisé une étude rétrospective concernant 60 arthroplasties totales de la hanche implantées chez 50 patients adultes, colligée au sevice de Traumatologie et de chirurgie orthopédique à l'Hôpital Militaire Avicenne de Marrakech sur une période étalée de Janvier 2010 au Décembre 2012. Nous avons évalué la prise en charge anesthésique: pré, per et postopératoire des patients opérés pour une PTH. La moyenne d’âge était de 56,5 ans, le sex-ratio était de 1,63 en faveur des hommes. L'indication prédominante était la coxarthrose primitive. L'anesthésie générale était la technique anesthésique la plus utilisée (66% des cas), l'intubation difficile était rencontrée chez 6% de nos patients. La durée moyenne de l'acte chirurgical était de 114 +/- 25,33 mn. 12% de nos patients ont présenté une hypotension artérielle peropératoire. L'incidence de la transfusion homologue perop était de 14%. Nous avons noté 08 cas de complications postop: 03 cas d'infection de la PTH 15 jours après l'intervention, 03 cas de descellement aseptique, 01 cas de luxation de PTH et 01 cas de descellement septique avec un recul moyen de 54 mois. PMID:27047619

  2. La radiothérapie du cancer de l'endomètre: expérience de l'institut national d'oncologie à propos de 52 cas

    PubMed Central

    Mezouri, Imane; Berhili, Soufiane; Mouhajir, Nawal; Bellefqih, Sara; Elkacemi, Hanan; Kebdani, Tayeb; Benjaafar, Noureddine

    2016-01-01

    Le cancer de l'endomètre est le cancer gynécologique le plus fréquent en occident. Il concerne principalement les femmes ménopausées. L'objectif de notre travail est de rapporter l'expérience du service de radiothérapie à l'Institut National d'Oncologie (INO) dans la prise en charge du cancer de l'endomètre. Nous avons analysé rétrospectivement 52 cas de cancer de l'endomètre traités dans le service de radiothérapie de l'INO entre 2007 à 2009. Les données collectées à partir des dossiers médicaux de nos patientes concernaient les aspects épidémiologiques, cliniques, thérapeutiques et évolutifs de ce cancer. La médiane d’âge des patientes était de 57 ans, 87% étaient ménopausées. Le délai moyen de consultation était de six mois. Le maitre symptôme était des métrorragies chez 51 patientes. Le diagnostic histologique a été porté sur un curetage biopsique de l'endomètre dans 51% des cas. L'examen anatomopathologique a montré un adénocarcinome endométrioïde dans 92% des cas. Après le bilan, 27% des patientes étaient stade I, 30% stade II, 20% stade III et 1% stade IVA selon la classification de la Fédération Internationale de Gynécologie Obstétrique (FIGO). Après la chirurgie, 51% des patientes ont reçu une radiothérapie externe. La dose délivrée était de 46 Gray (Gy). Une curiethérapie du fond vaginal a été délivrée chez toutes les patientes. Sur le plan évolutif, 83% des patientes étaient toujours suivies en situation de bon contrôle de leur maladie, 8% ont eu une récidive locorégionale et 4% avaient des métastases à distance. Ainsi, le cancer de l'endomètre est un cancer dont le traitement repose sur la chirurgie. La radiothérapie est le traitement adjuvant principal. PMID:27279969

  3. Les sepsis intra-abdominaux diffus post-operatoires: aspects épidémiologiques, diagnostiques et thérapeutiques au Service de Chirurgie Générale du CHU Aristide Le Dantec de Dakar

    PubMed Central

    Touré, Alpha Oumar; Cissé, Mamadou; Ka, Ibrahima; Dieng, Madieng; Konaté, Ibrahima; Ka, Ousmane; Touré, Cheikh Tidiane

    2014-01-01

    Les sepsis intra-abdominaux diffus postopératoires (SIADPO) ont encore une fréquence alarmante. Ils mettent rapidement en cause l'intégrité des grandes fonctions. Le but de cette étude était d’évaluer leur prise en charge. Il s'agissait d'une étude rétrospective descriptive sur 10 ans (janvier 2000 à décembre 2009) portant sur 45 cas de SIADPO. Nous avons étudié les aspects épidémiologiques, diagnostiques, thérapeutiques et pronostiques. Il s'agissait de 45 cas dont 25 hommes et 20 femmes avec un sex-ratio de 1,25. L’âge moyen des patients était de 34 ans avec des extrêmes de 20 et 70 ans. Le SIADPO survenait au décours d'une intervention septique en urgence dans 68,8% des cas. Le délai moyen de diagnostic était de 10 jours. Les signes cliniques étaient dominés par les troubles du transit (80%), la douleur abdominale (77,7%), la fièvre (66,7%), le météorisme abdominal (33%). Une hyperleucocytose a été retrouvée dans 60% des cas. Le liquide intra-abdominal était polymicrobien. Tous les patients ont bénéficié d'une laparotomie xipho-pubienne dans les 72 heures. Nous avons noté 82,2% de péritonites secondaires notamment post-opératoires et 17,8% de péritonites persistantes. Les étiologies étaient dominées par le lâchage de suture digestive ou gynécologique (66,7% des cas). La stomie digestive a été le geste le plus fréquemment réalisé (41%). La guérison est survenue chez 75,5%. La morbidité opératoire était de 42% faite de suppuration pariétale (10 cas), de fistule entérocutanée (6 cas), d’éviscération (2 cas). La mortalité était de 24,5% en rapport avec le retard diagnostique et les défaillances multi-viscérales. Les interventions septiques en urgence sont les plus grandes pourvoyeuses de SIADPO. La mortalité reste encore élevée en rapport avec la défaillance viscérale. La précocité du diagnostic et de la réintervention conditionnent ainsi le pronostic. PMID:25161748

  4. Kyste hydatique de la rate: à propos d'un cas

    PubMed Central

    Oumar, Touré Alpha; Ibrahima, Kâ; Sitor, Sarr Ibrahima; Mamadou, Cissé; Ibrahima, Konaté; Ousmane, Kâ; Madieng, Dieng; Abdarahmane, Dia; Tidiane, Touré Cheikh

    2013-01-01

    Le kyste hydatique de la rate est une affection rare en Afrique sub-saharienne. Il arrive en 3ème position après celui du foie et du poumon. Le traitement est essentiellement chirurgical en dehors d'un traitement médical ayant prouvé son efficacité. Nous rapportons le 1er cas pris en charge au Service de Chirurgie Générale du CHU Le Dantec à Dakar. Il s'agit d'un patient de 33 ans, originaire de Mauritanie, sans antécédent particulier qui nous a été adressé pour prise en charge d'un kyste splénique de découverte fortuite à l’échographie lors d'un bilan de routine avec sérologie hydatique positive à Eccinochoccus granulosa. L'examen clinique était sans particularité. La biologie retrouvait une thrombopénie à 88000 plaquettes/mm3. Le scanner montrait des kystes spléniques avec calcifications occupant plus de la moitié du parenchyme splénique. Il a bénéficié d'une splénectomie totale dont les suites ont été simples. Aucune particularité n’était notée après un suivi d'un an. Le kyste hydatique splénique est rare. Le traitement est chirurgical qu'il soit radical ou conservateur avec de bons résultats. PMID:23717708

  5. Hernie obturatrice étranglée: à propos de deux cas

    PubMed Central

    Younes, Aggouri; Hossam, Benhammane; Issam, Yazough; Imane, Toughrai; Said, Ait Laalim; Karim, Ibn Majdoub; Khalid, Mazaz

    2015-01-01

    La hernie obturatrice (HO) est rare. Elle est à l'origine de 0,2 à 1,6% des occlusions mécaniques de l'intestin grêle avec un taux de mortalité et morbidité après chirurgie est respectivement de 35 et 18%. Nous rapportons le cas de deux patientes chez qui le diagnostic de HO étranglée est établie dans le cadre du bilan d'une occlusion. La HO est une entité dont le diagnostic préopératoire est difficile en raison de la faible spécificité clinique. L'examen tomodensitométrique semble être une aide majeure au diagnostic étiologique. Mais une fois le diagnostic d'occlusion posé, une intervention en urgence permettra d'en préciser l’étiologie et d'en réaliser le traitement. Tout retard thérapeutique majore la mortalité et la morbidité. PMID:26113912

  6. Kyste hydatique mammaire primitive

    PubMed Central

    Boufettal, Houssine; Samouh, Naïma

    2015-01-01

    La localisation mammaire du kyste hydatique est exceptionnelle. De ce fait, le diagnostic est difficile avant l'examen anatomopathologique. Nous rapportons une observation d'un cas de kyste hydatique du sein chez une femme de 32 ans, qui consultait pour un nodule du sein, dont l'imagerie montrait une lésion en rétro-aréolaire du sein gauche, homogène, ovalaire et de contours réguliers. L'examen anatomopathologique objectivait un kyste hydatique à localisation mammaire. Les suites opératoires étaient simples. L'hydatidose est une maladie ubiquitaire, pouvant atteindre tous les organes. Le diagnostic peut être évoqué devant une masse kystique du sein avec des aspects très évocateurs à l'imagerie. La confirmation du diagnostic n'est confirmée qu'après une cytoponction ou une chirurgie d'exérèse qui réalise le traitement de cette pathologique. La négativité du bilan d'extension hydatique permet de retenir une localisation primitive de l’échinococcose. PMID:26185575

  7. Récidive de mélanome malin unguéal achromique: à propos d'un cas

    PubMed Central

    Benyass, Youssef; Chafry, Bouchaib; Koufagued, Kaldadak; Bouabid, Salim; Benchebba, Driss; Chagar, Belkacem

    2015-01-01

    Le mélanome malin unguéal représente 1,8 à 8,1% des mélanomes malins cutanés. Sa prise en charge s'adresse aujourd'hui aux praticiens de différentes spécialités. L'acte chirurgical initial est une étape incontournable du traitement curatif. La biopsie de la lésion doit être complète, afin de déterminer de façon exacte la profondeur de l'envahissement en cas de malignité. Nous rapportons un cas de mélanome malin achromique à localisation unguéal chez une femme. La chirurgie initiale consistait en une amputation transphalangienne proximale. L’évolution après deux ans était marquée par une récidive avec extension vers le carpe. Ayant subie une reprise chirurgicale avec une exérèse large. Le traitement des récidives est palliatif et vise à apporter un confort de vie au patient. Le principe du traitement fait appel à l'exérèse chirurgicale des lésions. Des alternatives thérapeutiques sont à l’étude. PMID:26977229

  8. Léiomyosarcome du pancréas: une tumeur de mauvais pronostic - cas clinique et revue de la littérature

    PubMed Central

    Laalim, Said Ait; Hijri, Fatim Zahra; Kamaoui, Imane; Hassani, Karim Ibn Majdoub; Toughai, Imane; Mazaz, Khalid

    2012-01-01

    Le léiomyosarcome (LMS) primitif du pancréas est une tumeur mésenchymateuse rare (0,1% des tumeurs pancréatiques), seulement 47 cas ont été publiés la littérature depuis 1951. Le diagnostique est basée sur l’immunohistochimie. C’est une tumeur très agressive et souvent découverte à un stade avancé. Nous rapportant le cas d’un patient de 40 ans qui présentait un léiomyosarcome primitif du pancréas de la queue du pancréas avec envahissement de la rate et la partie gauche du colon transverse. Une spléno-pancréatectomie caudale carcinologique avec une colectomie segmentaire était réalisée. Des nodules péritonéaux ont apparus 2 mois après l’intervention au niveau du site opératoire et le paient est décédé 3 mois en postopératoire. Le LMS primitif du pancréas doit être évoqués devant les volumineuses tumeurs du pancréas. Une chirurgie carcinologique est le seul traitement curatif. Le pronostic de ces tumeurs est mauvais et la médiane de survie de ces tumeurs ne dépasse pas 2 ans. PMID:23024830

  9. Electrical-shock prevention. Volume 1. Protection of maintenance personnel. Open file report 6 Apr 81-8 Dec 82

    SciTech Connect

    Morley, L.A.; Novak, T.; Trutt, F.C.

    1982-12-08

    The overall objective of this research was to investigate the application, economic, and safety considerations of electrical-shock prevention techniques applied to surface and underground mines. Volume I of this four-volume report is primarily concerned with the protection of maintenance personnel. The scope of the work is specified, electrical shock is defined, and needed ground-fault relay characteristics to prevent ventricular fibrillation are established. This is followed by an analysis of ac systems, a comparison of these systems with respect to body currents, the advantages and disadvantages of the various ground-fault protection techniques, and an analysis of dc systems for off-track vehicles. Summaries and synopses of each of the three remaining volumes are included.

  10. Heat Flow and Magnetization in the Oceanic Lithosphere. Ph.D. ThesisSemiannual Report, Nov. 1987 - Apr. 1988

    NASA Technical Reports Server (NTRS)

    Hayling, Kjell Lennart

    1988-01-01

    Two aspects of the processing and interpretation of satellite measurements of the geomagnetic field are described. One deals with the extraction of the part of the geomagnetic field that originates from sources in the earth's atmosphere. The other investigates the possibility of using the thermal state of the oceanic lithosphere to further constrain modelling and interpretation of magnetic anomalies. It is shown that some of the magnetic signal in crustal anomaly maps can be an artifact of the mathematical algorithms that have been used to separate the crustal field from the observed data. Strong magnetic anomalies can be distorted but are probably real, but weak magnetic anomalies can arise from leakage of power from short wavelengths, and will also appear in anomaly maps as repetitions of the strong crustal anomaly. The distortion and the ghost anomalies follow the magnetic dip lines in a way that is similar to actual MAGSAT anomaly fields. This phenomenon will also affect the lower degree spherical harmonic terms in the power spectrum of the crustal field. A model of the magnetic properties of the oceanic crust that has been derived from direct measurements of the rock magnetic properties of oceanic rocks is presented. The average intensity of magnetization in the oceanic crust is not strong enough to explain magnetic anomalies observed over oceanic areas. This is the case for both near surface observations (ship and aeromagnetic data) and satellite altitude observations. It is shown that magnetic sources in the part of the upper mantle that is situated above the Curie isotherm, if sufficiently strong, can produce satellite magnetic anomalies that are comparable to MAGSAT data. The method developed for the study of depth to the Curie isotherm and magnetic anomalies can also be used in inverse modelling of satellite magnetic anomalies when the model is to be adjusted with an annihilator.

  11. Gesellschaft fuer angewandte Mathematik und Mechanik, Scientific Annual Meeting, Universitaet Dortmund, West Germany, Apr. 1-4, 1986, Reports

    NASA Astrophysics Data System (ADS)

    Various papers on applied mathematics and mechanics are presented. The general topics addressed include: mechanics of fluids; numerical treatment of differential equations; optimization, decision theory, stochastics, and insurance mathematics; applied analysis and mathematical physics; and numerical analysis.

  12. New instrumental technique for the analysis of high-energy-content fuels. Final report, Apr-Dec 86

    SciTech Connect

    Hutte, R.

    1990-07-01

    The technical effort described herein was directed at determining the feasibility of using the Redox Chemiluminescence Detector (RCD) for the selective detection of cycloalkanes and antioxidants in jet fuels. Three catalysts (gold, palladium, and platinum) were prepared and evaluated at several reaction temperatures. The gold catalyst at 300 deg C produced the best selectivity for cycloalkanes (40:1 for hexane and 3:1 for nonane). As temperature was increased, however, the selectivity for cycloalkanes decreased. The palladium and platinum catalysts did not demonstrate adequate selectivity under the examined test conditions. Overall, the metal catalysts examined in this study did not exhibit sufficient selectivity to permit detection of cycloalkanes versus acyclic alkanes. The selectivity of the RCD for easily oxidized compounds (eg. phenols) versus hexane was typically 104 to 106. (JS)

  13. Reflective and refractive optical materials for earth and space applications; Proceedings of the Meeting, Orlando, FL, Apr. 4, 5, 1991

    SciTech Connect

    Riedl, M.J.; Hale, R.R.; Parsonage, T.B.

    1991-01-01

    The present conference discusses beryllium mirror design and fabrication, production of aspheric beryllium optical surfaces by HIP consolidation, the control of thermally induced porosity for the fabrication of beryllium optics, fine-grained beryllium optical coatings, light-absorbing beryllium baffle materials, and advanced broadband baffle materials. Also discussed are radiation-resistant optical glasses, a catalog of IR and cryooptical properties of selected materials, durable metal-dielectric mirror coatings, the optical stability of diffuse reflectance materials, and optical filters for space applications.

  14. Characterization, propagation, and simulation of infrared scenes; Proceedings of the Meeting, Orlando, FL, Apr. 16-20, 1990

    NASA Astrophysics Data System (ADS)

    Watkins, Wendell R.; Zegel, Ferdinand H.; Triplett, Milton J.

    1990-09-01

    Various papers on the characterization, propagation, and simulation of IR scenes are presented. Individual topics addressed include: total radiant exitance measurements, absolute measurement of diffuse and specular reflectance using an FTIR spectrometer with an integrating sphere, fundamental limits in temperature estimation, incorporating the BRDF into an IR scene-generation system, characterizing IR dynamic response for foliage backgrounds, modeling sea surface effects in FLIR performance codes, automated imaging IR seeker performance evaluation system, generation of signature data bases with fast codes, background measurements using the NPS-IRST system. Also discussed are: naval ocean IR background analysis, camouflage simulation and effectiveness assessment for the individual soldier, discussion of IR scene generators, multiwavelength Scophony IR scene projector, LBIR target generator and calibrator for preflight seeker tests, dual-mode hardware-in-the-loop simulation facility, development of the IR blackbody source of gravity-type heat pipe and study of its characteristic.

  15. OER/APR (Officer Effectiveness Report/Airman Performance Report) Administration: A Guide for Unit Level Monitors

    DTIC Science & Technology

    1985-04-01

    personnel action is generated and submitted to the CBPO which changes a member’s reporting official. Tn the case of Captain David T. Bent (refer to Figure...the Skills to work immediato and toughi problems--with outstanding results. ~’otential plus. I’e’s ready now--promote to colonel. Aggressive and

  16. 78 FR 17223 - Notice of Submission of Proposed Information Collection to OMB: Annual Progress Report (APR) for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-20

    ... requirements. This information assists HUD in understanding homeless clients and service needs at the local... information assists HUD in understanding homeless clients and service needs at the local level. HUD also uses...

  17. Proceedings of Tunnel Detection Symposium on Subsurface Exploration Technology (4th) held in Golden, Colorado on 26 - 29 Apr 1993

    DTIC Science & Technology

    1993-04-29

    characteristics such as intuition, telepathy , ESP, PSI, subconscious creativity and the likz. "Don’t do it Ruskey," they told me, "give them nuts and bolts." Nuts...basic shape of the homogeneous media response ( i.e. the primary wave). The synthetic waveforms 72 show good conformance with the field data. The minor...as a fracture halo surrounding the tunnel which is unaccounted for in the simulation. Figure 5 shows a suite of synthetic waveforms for an air tilled

  18. Microbial degradation of alkylbenzenes under sulfate-reducing and methanogenic conditions. Final report, May 89-Apr 91

    SciTech Connect

    Beller, H.R.; Edwards, E.A.; Grbic-Galic, D.; Reinhard, M.

    1991-07-01

    Aquifer solids and soils obtained from various hydrocarbon-contaminated sites were used to investigate the ability of indigenous microorganisms to degrade monoaromatic hydrocarbons under strictly anaerobic conditions. In anaerobic microcosms inoculated with fuel-contaminated soil from the Patuxent River site, toluene degradation occurred concomitantly with sulfate reduction and ferric iron reduction. Similar results were obtained with suspended enrichments derived from the microcosms. Stoichiometric data and other observations suggested that sulfate reduction was closely linked to toluene degradation, whereas iron reduction was a secondary, potentially abiotic, reaction between ferric iron and biogenic hydrogen sulfide. The presence of millimolar concentrations of amorphous Fe(OH)3 in Patuxent River microcosms and enrichments either greatly facilitated the onset of toluene degradation or accelerated the rate once degradation had begun. Fermentative/methanogenic microcosms and enrichments that degraded toluene and o-xylene without added exogenous electron acceptors (except CO2) were developed from creosote-contaminated Pensacola samples. The microcosms initially underwent an acclimation lag of several months; however, once the degradation of aromatic hydrocarbons was initiated, it proceeded at a relatively rapid rate, and it was complete (resulting in mineralization to CO2 and CH4). Benzene, ethylbenzene, and p-xylene were not degraded.

  19. La participation des parents a l'ecole primaire trente ans apres: un objectif encore a atteindre

    NASA Astrophysics Data System (ADS)

    Salomon, Anne; Comeau, Judith

    1998-03-01

    This study examines the perceptions which teachers, head teachers and parents have of the participation of parents in the running of primary schools. While participation has been widely advocated (in North America, Europe and Africa), it appears that there are still tensions between the school and the family. The study shows that parents who are members of school councils state that they favour participation while teachers express some doubts on the positive aspects. Headteachers are more convinced, however. A number of variables help to differentiate the results, such as environment (rural, semi-urban or urban), and the sub-group to which the respondents belong (parents who are members or non-members of school councils, and teachers of different grades). The discussion considers the need for dialogue and consideration of each person's position in the interest of creating conditions favourable to children's development.

  20. Evaluation of electrodialysis for chronic acid recovery and purification at Corpus Christi Army Depot. Final report, Oct 89-Apr 91

    SciTech Connect

    Davis, J.S.

    1991-09-01

    A large quantity of hazardous waste is generated during the maintenance, repair, and overhaul of a wide variety of military equipment at Army depots. Some of this waste is generated by the use of chromic acid solutions for chromium electroplating and the application and removal of chromate conversion coatings. Hazardous waste results when metal contamination builds up in the solutions to such a degree that the solutions must be disposed of as hazardous waste. Removal of this metal contamination should result in a lengthened bath life and reduced hazardous wate generation. As part of its pollution abatement and environmental control mission, the U.S. Army Toxic and Hazardous Materials Agency (USATHAMA) is pursuing R and D projects to assist depots in meeting the Army goal of a 50 percent reduction in hazardous waste by the end of 1992 compared with 1985 baseline levels. In one project, USATHAMA purchased, installed, operated, and evaluated an electrodialysis system on two chromic acid process solutions at Corpus Christi Army Depot (CCAD) in Corpus Christi, Texas. The objective of this task was to evaluate the system's ability to remove metal contamination and oxidize trivalent chromium (an impurity) to hexavalent chromium (chromic acid).

  1. Composite materials: Testing and design. Volume 9; Proceedings of the Ninth Symposium, Sparks, NV, Apr. 27-29, 1988

    SciTech Connect

    Garbo, S.P.

    1990-01-01

    This volume discusses topics on structural considerations and analysis of composite materials, delamination initiation and growth analysis, and damage mechanisms and test procedures. Papers are presented on certification testing methodology for fighter hybrid structure, the impact damage and residual strength analysis of composite panels with bonded stiffeners, and a failure analysis of bolted joints in composite laminates. Attention is given to the mechanics of instability-related delamination growth; delamination fracture between adhesive and adherends in bonded joints; matrix toughness, long-term behavior, and damage tolerance of notched graphite fiber-reinforced comoposite materials; and analytical and experimental investigations of composites using vibrothermography. Other papers are on the loading-rate sensitivity of open-hole composite specimens in compression, a failure criterion evaluation for composite materials, and experimental investigations and a model proposal on damage mechanisms in a reinforced carbon-carbon composite.

  2. Transonic aerodynamics of dense gases. M.S. Thesis - Virginia Polytechnic Inst. and State Univ., Apr. 1990

    NASA Technical Reports Server (NTRS)

    Morren, Sybil Huang

    1991-01-01

    Transonic flow of dense gases for two-dimensional, steady-state, flow over a NACA 0012 airfoil was predicted analytically. The computer code used to model the dense gas behavior was a modified version of Jameson's FL052 airfoil code. The modifications to the code enabled modeling the dense gas behavior near the saturated vapor curve and critical pressure region where the fundamental derivative, Gamma, is negative. This negative Gamma region is of interest because the nonclassical gas behavior such as formation and propagation of expansion shocks, and the disintegration of inadmissible compression shocks may exist. The results indicated that dense gases with undisturbed thermodynamic states in the negative Gamma region show a significant reduction in the extent of the transonic regime as compared to that predicted by the perfect gas theory. The results support existing theories and predictions of the nonclassical, dense gas behavior from previous investigations.

  3. Margin for In-Vessel Retention in the APR1400 - VESTA and SCDAP/RELAP5-3D Analyses

    SciTech Connect

    Joy Rempe; D. Knudson

    2004-12-01

    If cooling is inadequate during a reactor accident, a significant amount of core material could become molten and relocate to the lower head of the reactor vessel, as happened in the Three Mile Island Unit 2 (TMI-2) accident. If it is possible to ensure that the lower head remains intact so that relocated core materials are retained within the vessel, the enhanced safety associated with such plants can reduce concerns about containment failure and associated risk. For example, the enhanced safety of the Westinghouse Advanced 600 MWe pressurized water reactor (PWR) (AP600), which relied upon external reactor vessel cooling (ERVC) for in-vessel retention (IVR), resulted in the U.S. Nuclear Regulatory Commission (USNRC) approving the design without requiring certain conventional features common to existing light water reactors (LWRs). IVR of core melt is therefore a key severe accident management strategy adopted by some operating nuclear power plants and proposed for some advanced LWRs. However, it is not clear that currently proposed ERVC without additional enhancements could provide sufficient heat removal for higher-power reactors (up to 1500 MWe). Hence, a three-year, United States (U.S.) -Korean International Nuclear Energy Research Initiative (INERI) project was initiated in which the Idaho National Engineering and Environmental Laboratory (INEEL), Seoul National University (SNU), Pennsylvania State University (PSU), and the Korean Atomic Energy Research Institute (KAERI) explored options, such as enhanced ERVC performance and an enhanced in-vessel core catcher (IVCC), that have the potential to ensure that IVR is feasible for higher power reactors.

  4. Fugitive emission testing at the Kosovo coal gasification plant. Final task report Apr 79-Sep 81. [Yugoslavia

    SciTech Connect

    Honerkamp, R.L.; Dalrymple, D.A.

    1983-06-01

    The report summarizes results of a test program to characterize fugitive emissions from the Kosovo coal gasification plant in Yugoslavia, a test program implemented by the EPA in response to a need for representative data on the potential environmental impacts of Lurgi coal gasification technology. Major objectives of the fugitive emissions assessment were to: (1) determine the frequency of leak occurrence, (2) measure leak rates from leak sources, (3) estimate total fugitive emissions from leakage, and (4) compare the results to other fugitive emission test data. Study results show similarities to results of fugitive emission testing in U.S. oil refineries and organic chemical plants.

  5. Applications of artificial intelligence X: Machine vision and robotics; Proceedings of the Meeting, Orlando, FL, Apr. 22-24, 1992

    SciTech Connect

    Bowyer, K.W.

    1992-01-01

    Various papers on artificial intelligence in machine vision and robotics are presented. The general topics addressed include: design of a robot head, machine vision inspection techniques, segmentation of fused range and intensity imagery, parallel and VLSI architectures for machine vision, comparison of range image segmentation algorithms, state of the art in postcanny edge detection, simulation and visualization environments for autonomous robots, exploration of recognition by components representation and matching, reactive robotic control strategies, image processing techniques.

  6. Advanced development of diagnostics for non-ideal blast flows. Technical report 1 Apr 89-1 Jun 91

    SciTech Connect

    Modarress, D.; Hoeft, T.

    1992-07-01

    Investigations of non-ideal airblast are performed at the Ernst Mach Institute in a shock tube that simulates a radiation-induced thermal layer. Visualization techniques were adequate for overall study of the flow, but did not provide the detailed data for validation of computer codes. Under this contract three tasks were performed to provide needed data. The first task was to develop a software package for analysis of interferogram fringes. This package translates fringes shift due to the presence of helium into densities over the image area. This package was installed at EMI. The second task was to evaluate and test techniques for direct time-varying measurement of gas species concentration. Absorption spectroscopy of NO2 was selected to be used, but had corrosion problems and was abandoned. As a replacement, filtered Rayleigh scattering from Freon gas was identified. The third task was to fabricate and install a multi-location laser Doppler velocimeter system for the shock tube. This unit was installed in the shock tube and preliminary velocity measurements of flow over a rough surface were made.

  7. Design, Implementation and Validation of the Three-Wheel Holonomic Motion System of the Assistant Personal Robot (APR).

    PubMed

    Moreno, Javier; Clotet, Eduard; Lupiañez, Ruben; Tresanchez, Marcel; Martínez, Dani; Pallejà, Tomàs; Casanovas, Jordi; Palacín, Jordi

    2016-10-10

    This paper presents the design, implementation and validation of the three-wheel holonomic motion system of a mobile robot designed to operate in homes. The holonomic motion system is described in terms of mechanical design and electronic control. The paper analyzes the kinematics of the motion system and validates the estimation of the trajectory comparing the displacement estimated with the internal odometry of the motors and the displacement estimated with a SLAM procedure based on LIDAR information. Results obtained in different experiments have shown a difference on less than 30 mm between the position estimated with the SLAM and odometry, and a difference in the angular orientation of the mobile robot lower than 5° in absolute displacements up to 1000 mm.

  8. Digital and optical shape representation and pattern recognition; Proceedings of the Meeting, Orlando, FL, Apr. 4-6, 1988

    NASA Technical Reports Server (NTRS)

    Juday, Richard D. (Editor)

    1988-01-01

    The present conference discusses topics in pattern-recognition correlator architectures, digital stereo systems, geometric image transformations and their applications, topics in pattern recognition, filter algorithms, object detection and classification, shape representation techniques, and model-based object recognition methods. Attention is given to edge-enhancement preprocessing using liquid crystal TVs, massively-parallel optical data base management, three-dimensional sensing with polar exponential sensor arrays, the optical processing of imaging spectrometer data, hybrid associative memories and metric data models, the representation of shape primitives in neural networks, and the Monte Carlo estimation of moment invariants for pattern recognition.

  9. Nicotinic cholinergic receptors in rat brain. Annual report No. 3, 1 May 85-30 Apr 86

    SciTech Connect

    Kellar, K.J.

    1986-05-01

    We have compared the characteristics of the recognition sites for 3(H)acetylcholine and 3H(-)nicotine in rat brain and found that the pharmacology, distribution, disulfide bond requirement, and regulation by chronic administration of nicotine and soman are identical. From these studies we conclude that 3Hacetylcholine and 3H(-)nicotine recognize the same recognition site which has the characteristics expected of a nicotinic cholinergic receptor. We have also determined that 3Hacetylcholine of high specific radioactivity (80 Ci/mmol) is an excellent ligand with which to study muscarinic receptors that have high affinity for agonists. These receptors may represent a subtype of muscarinic receptors found in brain, heart, glands, an some smooth muscle. (JS)

  10. Computing Science and Statistics: Proceedings of the Symposium on Interface, 21-24 Apr 1991, Seattle, WA

    DTIC Science & Technology

    1991-01-01

    Finally ity for a scalar parameter. Technical Report a generic computer program has been developed for #9003, University of Toronto. 146 A.C.M. Wong... REPORT TYPE AND DATES COVERED 1 1992 Final 15 Mar 91- 14 Mar 92 4. TITLE AND SUBTITLE S. FUNDING NUMBERS Computing Science and Statistics, Interface󈨟... Generalization through Minimal Networks with Application to Forecasting Andreas S. Weigend and David E. Rumelhart, Stanford University XXIX. COMPUTATIONAL

  11. Sensors and sensor systems for guidance and navigation II; Proceedings of the Meeting, Orlando, FL, Apr. 22, 23, 1992

    NASA Astrophysics Data System (ADS)

    Welch, Sharon S.

    Topics discussed in this volume include aircraft guidance and navigation, optics for visual guidance of aircraft, spacecraft and missile guidance and navigation, lidar and ladar systems, microdevices, gyroscopes, cockpit displays, and automotive displays. Papers are presented on optical processing for range and attitude determination, aircraft collision avoidance using a statistical decision theory, a scanning laser aircraft surveillance system for carrier flight operations, star sensor simulation for astroinertial guidance and navigation, autonomous millimeter-wave radar guidance systems, and a 1.32-micron long-range solid state imaging ladar. Attention is also given to a microfabricated magnetometer using Young's modulus changes in magnetoelastic materials, an integrated microgyroscope, a pulsed diode ring laser gyroscope, self-scanned polysilicon active-matrix liquid-crystal displays, the history and development of coated contrast enhancement filters for cockpit displays, and the effect of the display configuration on the attentional sampling performance. (For individual items see A93-28152 to A93-28176, A93-28178 to A93-28180)

  12. Annual Performance Report. Bureau of Indian Education FFY 2011. Revised Clarification, May 17, 2013. APR Template-Part B

    ERIC Educational Resources Information Center

    Bureau of Indian Education, 2013

    2013-01-01

    During SY 2011-2012, the Bureau of Indian Education (BIE) continued their efforts to improve the validity and reliability of data reporting. BIE data collections are dependent on school level entry (self-reporting) into the Native American Student Information System (NASIS) or into the BIE's Annual Report from the schools. In addition, data…

  13. Measuring ocean waves from space; Proceedings of the Symposium, Johns Hopkins University, Laurel, MD, Apr. 15-17, 1986

    NASA Technical Reports Server (NTRS)

    Beal, Robert C. (Editor)

    1987-01-01

    Papers are presented on ocean-wave prediction; the quasi-universal form of the spectra of wind-generated gravity waves at different stages of their development; the limitations of the spectral measurements and observations of the group structure of surface waves; the effect of swell on the growth of wind wave; operational wave forecasting; ocean-wave models, and seakeeping using directional wave spectra. Consideration is given to microwave measurements of the ocean-wave directional spectra; SIR research; estimating wave energy spectra from SAR imagery, with the radar ocean-wave spectrometer, and SIR-B; the wave-measurement capabilities of the surface contour radar and the airborne oceanographic lidar; and SIR-B ocean-wave enhancement with fast-Fourier transform techniques. Topics discussed include wave-current interaction; the design and applicability of Spectrasat; the need for a global wave monitoring system; the age and source of ocean swell observed in Hurricane Josephine; and the use of satellite technology for insulin treatment.

  14. Wear of materials; Proceedings of the 9th International Conference, San Francisco, CA, Apr. 13-16, 1993

    NASA Astrophysics Data System (ADS)

    Ludema, Ken

    1993-04-01

    Various papers on friction, lubrication, and wear are presented. Some of the topics addressed are: machinability of steels and titanium alloys under lubrication, friction behavior of ceramic fiber-reinforced aluminum metal-matrix composites against a 440 C steel counterface, combined effect of speed and humidity on the wear and friction of silicon nitride, role of indentation fracture in free abrasive machining of ceramics, solid-particle erosion of in situ reinforced Si3N4, effects of microstructure on the wear transition of zirconia-toughened alumina, gross slip criteria in fretting, tribological behavior of unidirectional graphite-epoxy and carbon-PEEK composites. Also discussed are: failure of poly (ether ether ketone) in high speed contacts, tribological behavior of blends of polyether ether ketone and polyether imide, increasing wear resistance in polymer-based composites using radiation-modified polymeric additives, wear deformation of ordered Fe-Al intermetallic alloys, tribological stability of metallic materials at elevated temperatures, friction and wear of self-lubricating composites at temperatures to 450 C in vacuum, micromechanics of MoS2 lubrication, wear of selected materials and composites sliding against MoS2 films, wear reduction by pyrolytic carbon on tribosurfaces.

  15. Sensors and sensor systems for guidance and navigation II; Proceedings of the Meeting, Orlando, FL, Apr. 22, 23, 1992

    NASA Technical Reports Server (NTRS)

    Welch, Sharon S. (Editor)

    1992-01-01

    Topics discussed in this volume include aircraft guidance and navigation, optics for visual guidance of aircraft, spacecraft and missile guidance and navigation, lidar and ladar systems, microdevices, gyroscopes, cockpit displays, and automotive displays. Papers are presented on optical processing for range and attitude determination, aircraft collision avoidance using a statistical decision theory, a scanning laser aircraft surveillance system for carrier flight operations, star sensor simulation for astroinertial guidance and navigation, autonomous millimeter-wave radar guidance systems, and a 1.32-micron long-range solid state imaging ladar. Attention is also given to a microfabricated magnetometer using Young's modulus changes in magnetoelastic materials, an integrated microgyroscope, a pulsed diode ring laser gyroscope, self-scanned polysilicon active-matrix liquid-crystal displays, the history and development of coated contrast enhancement filters for cockpit displays, and the effect of the display configuration on the attentional sampling performance.

  16. Waste reduction for electroless nickel-plating solutions at U. S. Army depots. Final report, Oct 91-Apr 92

    SciTech Connect

    Davis, J.S.

    1992-06-10

    Waste minimization is one of the most pressing environmental issues currently facing U.S. Army depots. The U.S. Army Toxic and Hazardous Materials Agency (USATHAMA) conducts research and development to support Army depots in implementing technologies to reduce waste generation. The Joint Depot Environmental Panel (JDEP) identified electroless nickel (EN) plating, which is currently used at Corpus Christi Army Depot (CCAD), Red River Army Depot (RRAD), and Sacramento Army Depot (SAAD) as a target for waste minimization research. This report presents the results of an evaluation conducted by USA regarding minimizing waste from EN-plating operations. The objective of this evaluation was to formulate recommendations for depots regarding implementation of waste minimization technologies. This evaluation was performed through site visits, a literature search, and discussions with vendors of EN processes and decontamination technologies.

  17. Infrared imaging systems: Design, analysis, modeling, and testing II; Proceedings of the Meeting, Orlando, FL, Apr. 3-5, 1991

    NASA Astrophysics Data System (ADS)

    Holst, Gerald C.

    Topics addressed include MTF characteristics of a Scophony scene projector, design of an athermalized three-field-of-view infrared sensor, a 3D analysis framework and measurement methodology for imaging system noise, effects of phasing on MRT target visibility, a multisensor analysis tool, a computer simulation of stairing-array thermal imagers, and a validated CCD camera model. Also discussed are an end-to-end model for detection performance evaluation against scenario-specific targets, Wiener-matrix image restoration beyond tha sampling passband, thermal signature training for military observers, reporting data for arrays with many elements, determination of FLIR LOS stabilization errors, fixed-pattern-noise cancellation in linear pyro arrays, a SPRITE detector characterization through impulse response testing, sine wave measurements of SPRITE detector MTF.

  18. 75 FR 44847 - Proposed Collection; Comment Request for Forms 943, 943-PR, 943-A, and 943A-PR

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-29

    .../or continuing information collections, as required by the Paperwork Reduction Act of 1995, Public Law..., Employer's Annual Tax Return for Agricultural Employees, 943-PR, Planilla Para La Declarcion Anual De La Contribucion Federal Del Patrono De Empleados Agricolas, 943-A, Agricultural Employer's Record of Federal Tax...

  19. 78 FR 47051 - Proposed Collection; Comment Request for Forms 943, 943-PR, 943-A, and 943A-PR

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-02

    ... Law 104-13 (44 U.S.C. 3506(c)(2)(A)). Currently, the IRS is soliciting comments concerning Forms 943, Employer's Annual Tax Return for Agricultural Employees, 943-PR, Planilla Para La Declarcion Anual De La Contribucion Federal Del Patrono De Empleados Agricolas, 943-A, Agricultural Employer's Record of Federal Tax...

  20. Superconductivity applications for infrared and microwave devices; Proceedings of the Meeting, Orlando, FL, Apr. 19, 20, 1990

    NASA Technical Reports Server (NTRS)

    Bhasin, Kul B. (Editor); Heinen, Vernon O. (Editor)

    1990-01-01

    Various papers on superconductivity applications for IR and microwave devices are presented. The individual topics addressed include: pulsed laser deposition of Tl-Ca-Ba-Cu-O films, patterning of high-Tc superconducting thin films on Si substrates, IR spectra and the energy gap in thin film YBa2Cu3O(7-delta), high-temperature superconducting thin film microwave circuits, novel filter implementation utilizing HTS materials, high-temperature superconductor antenna investigations, high-Tc superconducting IR detectors, high-Tc superconducting IR detectors from Y-Ba-Cu-O thin films, Y-Ba-Cu0-O thin films as high-speed IR detectors, fabrication of a high-Tc superconducting bolometer, transition-edge microbolometer, photoresponse of YBa2Cu3O(7-delta) granular and epitaxial superconducting thin films, fast IR response of YBCO thin films, kinetic inductance effects in high-Tc microstrip circuits at microwave frequencies.

  1. Superconductivity applications for infrared and microwave devices II; Proceedings of the Meeting, Orlando, FL, Apr. 4, 5, 1991

    NASA Technical Reports Server (NTRS)

    Heinen, Vernon O. (Editor); Bhasin, Kul B. (Editor)

    1991-01-01

    Topics discussed include thin-film technology, microwave transmission lines and resonators, microwave devices and circuits, infrared detectors and bolometers, and superconducting junctions. Papers are presented on possible enhancement in bolometric response using free-standing film of YBa2Cu3O(x), aging and surface instability in high-Tc superconductors, epitaxial Tl2Ba2CaCu2O8 thin films on LaAlO3 and their microwave device properties, the performance of stripline resonators using sputtered YBCO films, and a coplanar waveguide microwave filter of YBa2Cu3O7. Attention is also given to the performance characteristics of Y-Ba-Cu-O microwave superconducting detectors, high-Tc bolometer developments for planetary missions, infrared detectors from YBaCuO thin films, high-temperature superconductor junction technology, and submillimeter receiver components using superconducting tunnel junctions.

  2. ACQUISITION AND RETENTION OF CROSS-CULTURAL INTERACTION SKILLS THROUGH SELF-CONFRONTATION. FINAL REPORT APR 1965-SEP 1965.

    ERIC Educational Resources Information Center

    EACHUS, HERBERT T.; KING, PHILIP H.

    AN EXPERIMENT TESTED THE RELATIVE EFFECTIVENESS OF TWO TECHNIQUES FOR TRAINING UNITED STATES AIR FORCE MILITARY ADVISORS IN CROSS CULTURAL COMMUNICATION SKILLS. RETENTION OF SKILLS OVER TIME AND EFFECTS OF ATTITUDE ON LEARNING WERE ALSO STUDIED. SUBJECTS PLAYED THE ROLE OF AN AIR FORCE CAPTAIN INTERACTING WITH A FOREIGN COUNTERPART, PLAYED BY A…

  3. Future European and Japanese remote-sensing sensors and programs; Proceedings of the Meeting, Orlando, FL, Apr. 1, 2, 1991

    SciTech Connect

    Slater, P.N.

    1991-01-01

    Consideration is given to the METEOSAT second-generation program, the ESA earth observation polar platform program, a new satellite for a climatology study in the tropics, a medium-resolution imaging spectrometer, a Michelson interferometer for passive atmosphere sounding, an optical mapping instrument, an optical sensor system for Japanese earth resources satellite 1, a synthetic aperture radar of JERS-1, an ocean color and temperature scanner for Advanced Earth-Observing Satellite (ADEOS), an interferometric monitor for greenhouse gasses for ADEOS. Attention is also given to Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) for EOS-A, short-wave infrared subsystem design status of ASTER, ASTER calibration concept, Japanese polar orbit platform program, and airborne and spaceborne thermal multispectral remote sensing.

  4. Granular activated carbon adsorption and fluid-bed reactivation at Manchester, New Hampshire. Final report Mar 77-Apr 82

    SciTech Connect

    Kittredge, D.; Beaurivage, R.; Paris, D.

    1983-10-01

    Treatment performances of virgin and reactivated GAC were evaluated during three reactivation-exhaustion cycles by measuring total organic carbon (TOC), trihalomethanes (THM), and trihalomethane formation potential (THMFP). GAC adsorptive capacity was measured using traditional test parameters including iodine number, molasses decolorizing index, BET, and pore-size distribution. The GAC was reactivated on-site by a 500 lb/hr fluidized-bed unit. Results of this study demonstrated that onsite reactivation was a cost-effective method of restoring the adsorptive properties of spent GAC. During a 10-month period, more than 1.8 million lb of GAC was reactivated at a total cost of less than 22 cents/lb as compared with a delivered cost of 61.5 cents/lb for virgin GAC. The average total carbon loss resulting from transportation and reactivation was 11.5% by volume.

  5. Space Electrochemical Research and Technology Conference, 3rd, NASA Lewis Research Center, Cleveland, OH, Apr. 9, 10, 1991, Proceedings

    NASA Technical Reports Server (NTRS)

    Warshay, Marvin (Editor)

    1991-01-01

    The proceedings of NASA's third Space Electrochemical Research and Technology (SERT) conference are presented. The objective of the conference was to assess the present status and general thrust of research and development in those areas of electrochemical technology required to enable NASA missions in the next century. The conference provided a forum for the exchange of ideas and opinions of those actively involved in the field, in order to define new opportunities for the application of electrochemical processes in future NASA missions. Papers were presented in three technical areas: the electrochemical interface, the next generation in aerospace batteries and fuel cells, and electrochemistry for nonenergy storage applications.

  6. Copper Mountain Conference on Multigrid Methods, 4th, Copper Mountain, CO, Apr. 9-14, 1989, Proceedings

    SciTech Connect

    Mandel, J. Mccormick, S.F.; Farhat, C.; Dendy, J.E. Jr.; Lonsdale, G.

    1989-01-01

    Recent advances in multigrid methods (MGMs) for the numerical solution of fluid-dynamics problems are discussed in reviews and reports. Topics addressed include MGMs for nonconforming finite elements, a parallel MGM algorithm, an MGM-like semiiterative algorithm for the massively parallel solution of large-scale finite-element systems, multilevel convergence acceleration for viscous and turbulent transonic flows computed with a cell-vertex method, and domain-reduction methods. Consideration is given to MGMs for first-order systems, MGMs for the compressible Navier-Stokes equations, an MGM-based solution technique for incompressible flow, a parallel MGM for data-driven multiprocessor systems, MGMs for the Euler equations, parallel MGM algorithms and computer vision applications, and a comparison of Crank-Nicolson and waveform-relaxation MGMs on a hypercube computer.

  7. On-site treatment of creosote and pentachlorophenal sludges and contaminated soil. Research report, Jan 88-Apr 90

    SciTech Connect

    McGinnis, G.D.; Borazjani, H.; Pope, D.F.; Strobel, D.A.; McFarland, L.K.

    1991-05-01

    Information is presented for quantitative evaluation of treatment potential for creosote and pentachlorophenol (PCP) wood treating contaminants in soil systems. The study was conducted in three phases: (1) Characterization, (2) treatability screening and (3) field evaluation. Data generated in phases 1 and 2 were discussed in a previous EPA Report (EPA/-600/2-88-055). The report provides review of data generated during phases 1 and 2 plus discussion of data generated during the two-year field evaluation study. Results from the three-phase study indicated that creosote contaminants, i.e., polycyclic aromatic hydrocarbon (PAH) compounds, and PCP are subject to degradation in soil systems; loading rates and previous exposure of site soil to particular contaminants were identified as important factors in determining rates of transformation for a particular site. Although populations of PAH and PCP acclimated organisms increased markedly when these compounds were applied to test soils, no correlation was found between microbial population levels and transformation rates for specific compounds of concern. Migration of compounds of interest was negligible except in a highly sandy soil from one of the eight sites for which column leaching studies were conducted.

  8. Calibration of passive remote observing optical and microwave instrumentation; Proceedings of the Meeting, Orlando, FL, Apr. 3-5, 1991

    NASA Technical Reports Server (NTRS)

    Guenther, Bruce W. (Editor)

    1991-01-01

    Various papers on the calibration of passive remote observing optical and microwave instrumentation are presented. Individual topics addressed include: on-board calibration device for a wide field-of-view instrument, calibration for the medium-resolution imaging spectrometer, cryogenic radiometers and intensity-stabilized lasers for EOS radiometric calibrations, radiometric stability of the Shuttle-borne solar backscatter ultraviolet spectrometer, ratioing radiometer for use with a solar diffuser, requirements of a solar diffuser and measurements of some candidate materials, reflectance stability analysis of Spectralon diffuse calibration panels, stray light effects on calibrations using a solar diffuser, radiometric calibration of SPOT 23 HRVs, surface and aerosol models for use in radiative transfer codes. Also addressed are: calibrated intercepts for solar radiometers used in remote sensor calibration, radiometric calibration of an airborne multispectral scanner, in-flight calibration of a helicopter-mounted Daedalus multispectral scanner, technique for improving the calibration of large-area sphere sources, remote colorimetry and its applications, spatial sampling errors for a satellite-borne scanning radiometer, calibration of EOS multispectral imaging sensors and solar irradiance variability.

  9. 48 CFR 1552.235-75 - Access to Toxic Substances Control Act Confidential Business Information (APR 1996).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... handling CBI while working under the contract will be required to follow the procedures contained in the security manual entitled “TSCA Confidential Business Information Security Manual.” These procedures include...

  10. Truck design optimization project. Phase II: Type II Truck test results report. Technical report Apr-Dec 80

    SciTech Connect

    Peacock, R.A.; Gibson, D.W.

    1981-12-01

    The purpose of the Type II Truck Test Program was to obtain performance data on several Type II (or premium) freight car trucks in order to characterize their operational behavior. Data were acquired in the performance regimes of curve negotiation, lateral stability, trackability, and ride quality. Tests were also conducted to obtain rolling resistance data as part of the fuel consumption study. Data on the Longitudinal coupler forces were used to compare the relative ability of various trucks to reduce rolling resistance and flanging forces, thus improving fuel consumption. The test program was designed to provide direct comparison measurements, wherever possible, with the Type I Truck tested earlier in TDOP Phase II. Seven Type II trucks were tested over the same test zones used during Type I testing. This report documents the changes to the instrumentation and equipment developed for Type I testing which were made for testing Type II trucks. Descriptions of the testing of each truck are presented, as are the procedures for data acquisition and reduction. Additionally, the report contains five appendices: Wheelset Calibration Data, Bearing Adapter Calibration Data, Type II Truck Test Plan and Procedure, Data Reduction Equations, and Transducer Location Measurement Data. The performance data gathered during testing will be used to formulate performance specifications for Type II trucks.

  11. Applications of artificial intelligence X: Knowledge-based systems; Proceedings of the Meeting, Orlando, FL, Apr. 22-24, 1992

    SciTech Connect

    Biswas, G. )

    1992-01-01

    The present conference discusses cognitive mapping as a knowledge-engineering tool, inconsistency checking, abductive signal interpretation for NDE, hypotheticodeductive diagnoses, a parallel architecture for a multiple-input fuzzy logic controller, fuzzy-concept formation, and a case-associative mobile-robot planning system. Also considered are symbolic planning with metric time, the acquisition of teleological descriptions, genetic algorithm learning of scheduling heuristics, dynamical networks for pattern recognition, and an automated AI-based designer of electrical distribution systems.

  12. Computer modelling in crystal growth from the melt; Proceedings of the First NATO Workshop, Parma, Italy, Apr. 6, 7, 1989

    NASA Astrophysics Data System (ADS)

    Mueller, G.; Hurle, D. T. J.; Wenzl, H.

    1989-09-01

    This volume includes papers on three-dimensional time-dependent modeling of the Marangoni convection in zone melting configurations for GaAs, the real-time modeling and adaptive control of Czochralski growth, species transport in magnetic field Gzochralski growth, and Czochralski growth of silicon under an axial magnetic field. Consideration is also given to the effect of a shaped magnetic field on Czochralski silicon growth, a numerical analysis of heat transfer in LEC growth of GaAs, temperature and stress-field calculations in indium phosphide during LEC growth, and a numerical method for reducing stress level in GaAs crystals. Other papers are on a numerical simulation of oscillatory convection in semiconductor melts, linear and nonlinear analysis of the Hadley circulation, and the influence of the Prandtl number on laminar natural convection in a cylinder caused by g-jitter.

  13. Vingt ans après (Twenty years after). Comment on "Disentangling DNA molecules" by Alexander Vologodskii

    NASA Astrophysics Data System (ADS)

    Grosberg, Alexander Y.

    2016-09-01

    The effect of DNA topology simplification by type II topoisomerase enzymes was discovered experimentally by Rybenkov et al. [1] 20 years ago - which motivates me to borrow the title for this comment from Alexandre Dumas [2]. Ever since the original discovery, the effect keeps entertaining theorists - but the most surprising fact is that the original experiment was never repeated, let alone improved. I do not understand why it is so. In my opinion, there is an acute need of new experiments, not only repeating the original measurements, but also examining numerous other aspects of the phenomenon. In this sense, the review [3] by Vologodskii, one of the original discoverers, is both timely and important. In his review, Vologodskii concentrates on what I would call mechanical aspect of the problem - how bent are T- and G-segments, what kinds of juxtaposition are relevant, etc. The importance of these issues notwithstanding, I want to complement this approach, and to consider in greater detail the thermodynamics of the process. My main points are as follows: action of topo II enzyme violates detailed balance for DNA, leading to circular currents and dissipation (which is indeed quite a common occurrence in many living systems). These currents are potentially observable, and dissipation measurable, which should challenge experimenters. The main goal of this comment is to show how general phenomenological point of view allows to formulate theoretical prediction for the energy dissipation rate.

  14. Nicotinic cholinergic receptors in rat brain. Annual report No. 1, 1 May 83-30 Apr 84

    SciTech Connect

    Kellar, K.J.

    1984-06-02

    We have examined the molecular bond requirements of 3Hacetylcholine 3HACh nicotinic binding sites in rat brain. Reduction of disulfide bonds in vitro with the reducing agent dithiothreitol (DTT) resulted in a decrease in the number of 3HACh binding sites that could be measured, but the affinity of the remaining sites was unaltered. The effect of DTT was concentration-dependent, and it was reversed by reoxidation of the reduced disulfide bonds, with 5,5-dithiobis-2-nitrobenzoic acid. The reversibility of the DTT effect was prevented by p-chloromercuribenzoic acid, which forms thiol complexes with exposed sulfhydryl groups. The data indicate that disulfide bonds at or near the 3HACh recognition site are critical for binding of acetylcholine.

  15. Applications of artificial intelligence 1993: Machine vision and robotics; Proceedings of the Meeting, Orlando, FL, Apr. 14-16, 1993

    SciTech Connect

    Boyer, K.L.; Stark, L.

    1993-01-01

    Various levels of machine vision and robotics are addressed, including object recognition, image feature extraction, active vision, stereo and matching, range image acquisition and analysis, sensor models, motion and path planning, and software environments. Papers are presented on integration of geometric and nongeometric attributes for fast object recognition, a four-degree-of-freedom robot head for active computer vision, shape reconstruction from shading with perspective projection, fast extraction of planar surfaces from range images, and real-time reconstruction and rendering of three-dimensional occupancy maps.

  16. Thematic Conference on Geologic Remote Sensing, 8th, Denver, CO, Apr. 29-May 2, 1991, Proceedings. Vols. 1 & 2

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The proceedings contain papers discussing the state-of-the-art exploration, engineering, and environmental applications of geologic remote sensing, along with the research and development activities aimed at increasing the future capabilities of this technology. The following topics are addressed: spectral geology, U.S. and international hydrocarbon exporation, radar and thermal infrared remote sensing, engineering geology and hydrogeology, mineral exploration, remote sensing for marine and environmental applications, image processing and analysis, geobotanical remote sensing, and data integration and geographic information systems. Particular attention is given to spectral alteration mapping with imaging spectrometers, mapping the coastal plain of the Congo with airborne digital radar, applications of remote sensing techniques to the assessment of dam safety, remote sensing of ferric iron minerals as guides for gold exploration, principal component analysis for alteration mappping, and the application of remote sensing techniques for gold prospecting in the north Fujian province.

  17. Assessment of combined effects of blast and fire on personnel survivability. Final report 3 Apr 7-31 Jan 81

    SciTech Connect

    Longinow, A.; Waterman, T.E.; Takata, A.N.

    1982-06-01

    The objective of the study described was (1) to perform a preliminary analysis of hazards to sheltered personnel in a blast-fire environment produced by the detonation of a 1 MT nuclear weapon near the ground surface, and (2) to lay the basic ground work for developing a consistent, formal methodology for estimating the probability of people survival in a blast-fire environment.

  18. Noninvasive determination of respiratory ozone absorption: Development of a fast-responding ozone analyzer. Research report, Jun 88-Apr 90

    SciTech Connect

    Ultman, J.S.; Ben-Jebria, A.

    1991-01-01

    An ozone analyzer and an ozone bolus generator were developed and tested for future use in noninvasive measurements of ozone absorption along the human respiratory tract using the bolus-response technique. The analyzer, based on the chemiluminescent reaction of ozone with 2-methyl-2-butene, is sufficiently rapid and sensitive to measure changes in ozone concentration during a four-second breathing period at quiet respiratory flowrates of 300 mL/sec in human subjects. Its performance characteristics include a 90 percent step-response time of 110 msec, a linear calibration from 0.03 to 10 ppm ozone, a signal-to-noise ratio of 30 at 0.5 ppm ozone, and a minimum detection limit of 0.017 ppm ozone. The ozone bolus generator can produce single boluses containing as little as 0.35 micro g ozone in a volume of 19 mL, with a peak ozone fraction of up to 4 ppm. The analyzer and bolus generator were tested in bolus-response experiments at steady air flowrates of 50 to 200 mL/sec in excised pig and sheep tracheas. Twenty-five to 50 percent of the ozone introduced into the trachea was absorbed. Analysis of the mathematical moments of the bolus input and response curves and comparison to predictions of a diffusion theory indicate that ozone absorption is limited by diffusion processes in the airway lumen.

  19. Conference on Semi-Insulating III-V Materials (2nd), held 19-21 Apr 82, Evian (France),

    DTIC Science & Technology

    1983-02-28

    Dist Special 19. KEY WORDS (Continue on reverse side If neceary mud Identity by block numb ) Semiconductor devices Field effect transitors Integrated...Sun Tongnien (Hebei Semiconductor pit density. The W Research Institute, People’swith the etch ites of w Republic of China), and a compre-was...of impurities in touched on the topic of residual III-V semiconductors . The boron impurities in undoped GaAs, techniques discussed included a topic

  20. Long-term monitoring of the earth's radiation budget; Proceedings of the Meeting, Orlando, FL, Apr. 17, 18, 1990

    NASA Technical Reports Server (NTRS)

    Barkstrom, Bruce R. (Editor)

    1990-01-01

    The uses of the broadband flux measurements as well as the improvements in the Earth Radiation Budget Experiment in instrumentation and data reduction are summarized. Scientific uses of earth-radiation budget data are discussed, along with a perspective on the instrumentation giving a new foundation for studies of the radiation budget, with emphasis on calibration and long-term stability. Cloud identification and angular modeling are covered including angular dependence models for radiance to flux conversion and the pattern recognition of clouds and ice in polar regions. The surface-radiation budget and atmospheric radiative flux divergence from the Clouds and Earth Radiant Energy System are covered, and time dependence of the earth's radiation fields, determination of the outgoing longwave radiation and its diurnal variations are considered.

  1. Digital and optical shape representation and pattern recognition; Proceedings of the Meeting, Orlando, FL, Apr. 4-6, 1988

    SciTech Connect

    Juday, R.D.

    1988-01-01

    The present conference discusses topics in pattern-recognition correlator architectures, digital stereo systems, geometric image transformations and their applications, topics in pattern recognition, filter algorithms, object detection and classification, shape representation techniques, and model-based object recognition methods. Attention is given to edge-enhancement preprocessing using liquid crystal TVs, massively-parallel optical data base management, three-dimensional sensing with polar exponential sensor arrays, the optical processing of imaging spectrometer data, hybrid associative memories and metric data models, the representation of shape primitives in neural networks, and the Monte Carlo estimation of moment invariants for pattern recognition.

  2. ACQUISITION AND RETENTION OF CROSS-CULTURAL INTERACTION SKILLS THROUGH SELF-CONFRONTATION. FINAL REPORT APR 1965-SEP 1965.

    ERIC Educational Resources Information Center

    EACHUS, HERBERT T.; KING, PHILIP H.

    AN EXPERIMENT TESTED THE RELATIVE EFFECTIVENESS OF TWO TECHNIQUES FOR TRAINING UNITED STATES AIR FORCE MILITARY ADVISORS IN CROSS CULTURAL COMMUNICATION SKILLS. RETENTION OF SKILLS OVER TIME AND EFFECTS OF ATTITUDE ON LEARNING WERE ALSO STUDIED. SUBJECTS PLAYED THE ROLE OF AN AIR FORCE CAPTAIN INTERACTING WITH A FOREIGN COUNTERPART, PLAYED BY A…

  3. Metal matrix composites: Testing, analysis, and failure modes; Proceedings of the Symposium, Sparks, NV, Apr. 25, 26, 1988

    NASA Technical Reports Server (NTRS)

    Johnson, W. S. (Editor)

    1989-01-01

    The present conference discusses the tension and compression testing of MMCs, the measurement of advanced composites' thermal expansion, plasticity theory for fiber-reinforced composites, a deformation analysis of boron/aluminum specimens by moire interferometry, strength prediction methods for MMCs, and the analysis of notched MMCs under tensile loading. Also discussed are techniques for the mechanical and thermal testing of Ti3Al/SCS-6 MMCs, damage initiation and growth in fiber-reinforced MMCs, the shear testing of MMCs, the crack growth and fracture of continuous fiber-reinforced MMCs in view of analytical and experimental results, and MMC fiber-matrix interface failures.

  4. Surface-crack growth: Models, experiments, and structures; Proceedings of the Symposium, Sparks, NV, Apr. 25, 1988

    NASA Technical Reports Server (NTRS)

    Reuter, Walter G. (Editor); Underwood, John H. (Editor); Newman, James C., Jr. (Editor)

    1990-01-01

    The present volume on surface-crack growth modeling, experimental methods, and structures, discusses elastoplastic behavior, the fracture analysis of three-dimensional bodies with surface cracks, optical measurements of free-surface effects on natural surfaces and through cracks, an optical and finite-element investigation of a plastically deformed surface flaw under tension, fracture behavior prediction for rapidly loaded surface-cracked specimens, and surface cracks in thick laminated fiber composite plates. Also discussed are a novel study procedure for crack initiation and growth in thermal fatigue testing, the growth of surface cracks under fatigue and monotonically increasing load, the subcritical growth of a surface flaw, surface crack propagation in notched and unnotched rods, and theoretical and experimental analyses of surface cracks in weldments.

  5. Certain effects of plasma jetting across and along magnetic fields. Final report 1 Dec 77-30 Apr 81

    SciTech Connect

    Sperling, J.L.; Krall, N.A.

    1981-04-30

    We examine certain plasma effects associated with plasma jetting across and along magnetic field lines during the early-time phase of high-altitude nuclear events. It is shown that plasma jetting across the magnetic field may lead to prompt striations at higher altitudes (well in excess of four hundred kilometers) following a STARFISH type of nuclear burst. Superthermal ions with velocities less than the maximum velocity can participate in the striation formation. It is also demonstrated that ions and electrons travelling along magnetic field lines can be pitch angle scattered by waves through a cyclotron resonance process. An example is presented which shows that ion-cyclotron resistivity caused by interaction with Alfven waves can slow the motion of oxygen ions along magnetic field lines following a nuclear burst. The implication of cyclotron resistivity is that high-energy particles deposit their energy closer to their source than would otherwise be predicted.

  6. APRES Measurement of Highly Overdoped Bi_2Sr_2CaCu_2O_8+δ - Fermi Liquid-like?

    NASA Astrophysics Data System (ADS)

    Yusof, Zikri; Wells, B. O.; Valla, T.; Fedorov, A. V.; Johnson, P. D.; Li, Q.; Gu, G. D.; Koshizuka, N.; Kendziora, C.; Jian, Sha; Hinks, D. G.

    2001-03-01

    We present results from the study of a highly overdoped Bi_2Sr_2CaCu_2O_8+ δ (Bi2212) with a T_c=51K using high resolution angle-resolved photoemission spectroscopy (ARPES). These results will be compared to those from the lower doped cuprates, and also a 2D metal Mo(110) surface state. This overdoped cuprate shows properties that are different than the optimally and underdoped Bi2212. The temperature dependent spectra near the (π,0) point show the presence of the sharp peak well above T_c. Along the nodal direction, there is no noticeable change in the band dispersion below and above T_c. From the data, we obtain both the real and imaginary parts of the self-energy. The overall results show that this overdoped cuprate appears to be more Fermi Liquid-like than the optimally and underdoped ones. However, these overdoped spectra are not easily understood as FL when compared to the Mo(110) spectra. We discuss the experimental results which show that this overdoped Bi2212 has characteristics that fall in between the metallic Mo(110) and the optimally/underdoped cuprates. Work supported in part by Dept. of Energy under contract number DE-AC02-98CH10886, DE-FG02-00ER45801, DOE-BES W-31-109-ENG-38, and in part by the New Energy and Industrial Technology Development Organization, Australia.

  7. Design, Implementation and Validation of the Three-Wheel Holonomic Motion System of the Assistant Personal Robot (APR)

    PubMed Central

    Moreno, Javier; Clotet, Eduard; Lupiañez, Ruben; Tresanchez, Marcel; Martínez, Dani; Pallejà, Tomàs; Casanovas, Jordi; Palacín, Jordi

    2016-01-01

    This paper presents the design, implementation and validation of the three-wheel holonomic motion system of a mobile robot designed to operate in homes. The holonomic motion system is described in terms of mechanical design and electronic control. The paper analyzes the kinematics of the motion system and validates the estimation of the trajectory comparing the displacement estimated with the internal odometry of the motors and the displacement estimated with a SLAM procedure based on LIDAR information. Results obtained in different experiments have shown a difference on less than 30 mm between the position estimated with the SLAM and odometry, and a difference in the angular orientation of the mobile robot lower than 5° in absolute displacements up to 1000 mm. PMID:27735857

  8. Orbital mechanics and mission design; Proceedings of the AAS/NASA International Symposium, Greenbelt, MD, Apr. 24-27, 1989

    NASA Technical Reports Server (NTRS)

    Teles, Jerome (Editor)

    1989-01-01

    The present conference discusses topics in LEO mechanics, the earth-sun-moon orbital regime, space navigation, and lunar and planetary missions. Attention is given to an improved technique for passive eccentricity control, H-I launch vehicle mission planning, glideslope approaches, the control of Space Station-based tethered systems, rendezvous operations in GEO, launch-window expansion and trajectory correction for the First Lunar Swingby, the nature of lunar gravity assists, and the numerical determination of libration-point trajectories with solar exclusion zone-avoiding out-of-plane maneuvers. Also discussed are the interferometric tracking of multiple spacecraft, an improved determination of Martian satellite orbits, the Magellan Venus Mapping Mission, the Mars Rover Sample Return Mission, round-trip trajectories for manned Mars exploration, advanced missions using fusion propulsion, Vesta trajectories and navigation, and Voyager interstellar mission design.

  9. Intoxication mortelle après ingestion accidentelle de xylocaine visqueuse à 2% chez une jeune enfant.

    PubMed

    Nisse, P; Lhermitte, M; Dherbecourt, V; Fourier, C; Leclerc, F; Houdret, N; Mathieu-Nolf, M

    2002-01-01

    We report a case of fatal intoxication with 2% viscous lidocaine. A 18 month old infant was admitted after malaise and cardiorespiratory arrest at home. He was resuscitated, then seizures appeared before arrival at the hospital. Treatment was symptomatic, including cardiorespiratory resuscitation and administration of anticonvulsants. Identification of lidocaine and its metabolite monoethylglycinexylidide (MEGX) MEGX was performed after organic extraction by High Performance Liquid Chromatography (HPLC) with Diode Array Detection (DAD); the serum concentrations, determined by Fluorescence Polarisation Immuno Assay (FPIA), were : 1,1 μg / ml for lidocaine and 0,94 μg / ml for MEGX (H+7) and 0,30 μg / ml for the lidocaine (Day+1). Neurotoxic manifestations appear at lower concentrations than cardiotoxic symptoms which are correlated with plasma levels of lidocaine. The toxic symptoms begin with headache, hallucinations, seizure, coma, respiratory arrest and circulatory collapse. The toxic symptoms can persist even after the decrease of lidocaine concentration under therapeutic levels. There is no antidote and acute lidocaine toxicity is managed with supportive therapy (diazepam for seizures, intubation, chronotropic agents). Considering the gravity of these poisonings which remain rare, the 2% viscous lidocaine prescription is forbidden for children under 6 years old.

  10. Real-time image processing II; Proceedings of the Meeting, Orlando, FL, Apr. 16-18, 1990

    NASA Technical Reports Server (NTRS)

    Juday, Richard D. (Editor)

    1990-01-01

    The present conference discusses topics in the fields of feature extraction and implementation, filter and correlation algorithms, optical correlators, high-level algorithms, and digital image processing for ranging and remote driving. Attention is given to a nonlinear filter derived from topological image features, IR image segmentation through iterative thresholding, orthogonal subspaces for correlation masking, composite filter trees and image recognition via binary search, and features of matrix-coherent optical image processing. Also discussed are multitarget tracking via hybrid joint transform correlator, binary joint Fourier transform correlator considerations, global image processing operations on parallel architectures, real-time implementation of a differential range finder, and real-time binocular stereo range and motion detection.

  11. High power lasers and their industrial applications; Proceedings of the Meeting, Innsbruck, Austria, Apr. 15-18, 1986

    NASA Astrophysics Data System (ADS)

    Schuoecker, Dieter

    1986-01-01

    Papers are presented on the discharge behavior of an RF excited high power CO2 laser at different excitation frequencies; high power CO2 lasers for materials processing; a semiconductive preionization technique; high power Nd lasers for industrial applications; high power light transmission in optical waveguides; beam delivery systems for high power lasers; and quality control for high power CO2 laser optics. Topics discussed include the monitoring of laser material processes; measuring the quality of high power laser beams; the physics of laser material processing; metal precision drilling with lasers; and the evolution of microstructure for laser clad Fe-Cr-Mn-C alloys. Consideration is given to robotic manipulation for laser processing; laser cutting; the use of the laser versus the electron beam in welding the surface treatments; high power laser safety; and laser protective filters for the visible and near-IR spectrum.

  12. Surface-crack growth: Models, experiments, and structures; Proceedings of the Symposium, Sparks, NV, Apr. 25, 1988

    NASA Technical Reports Server (NTRS)

    Reuter, Walter G. (Editor); Underwood, John H. (Editor); Newman, James C., Jr. (Editor)

    1990-01-01

    The present volume on surface-crack growth modeling, experimental methods, and structures, discusses elastoplastic behavior, the fracture analysis of three-dimensional bodies with surface cracks, optical measurements of free-surface effects on natural surfaces and through cracks, an optical and finite-element investigation of a plastically deformed surface flaw under tension, fracture behavior prediction for rapidly loaded surface-cracked specimens, and surface cracks in thick laminated fiber composite plates. Also discussed are a novel study procedure for crack initiation and growth in thermal fatigue testing, the growth of surface cracks under fatigue and monotonically increasing load, the subcritical growth of a surface flaw, surface crack propagation in notched and unnotched rods, and theoretical and experimental analyses of surface cracks in weldments.

  13. Metal matrix composites: Testing, analysis, and failure modes; Proceedings of the Symposium, Sparks, NV, Apr. 25, 26, 1988

    NASA Technical Reports Server (NTRS)

    Johnson, W. S. (Editor)

    1989-01-01

    The present conference discusses the tension and compression testing of MMCs, the measurement of advanced composites' thermal expansion, plasticity theory for fiber-reinforced composites, a deformation analysis of boron/aluminum specimens by moire interferometry, strength prediction methods for MMCs, and the analysis of notched MMCs under tensile loading. Also discussed are techniques for the mechanical and thermal testing of Ti3Al/SCS-6 MMCs, damage initiation and growth in fiber-reinforced MMCs, the shear testing of MMCs, the crack growth and fracture of continuous fiber-reinforced MMCs in view of analytical and experimental results, and MMC fiber-matrix interface failures.

  14. Thematic Conference on Geologic Remote Sensing, 8th, Denver, CO, Apr. 29-May 2, 1991, Proceedings. Vols. 1 2

    SciTech Connect

    Not Available

    1991-01-01

    The proceedings contain papers discussing the state-of-the-art exploration, engineering, and environmental applications of geologic remote sensing, along with the research and development activities aimed at increasing the future capabilities of this technology. The following topics are addressed: spectral geology, US and international hydrocarbon exporation, radar and thermal infrared remote sensing, engineering geology and hydrogeology, mineral exploration, remote sensing for marine and environmental applications, image processing and analysis, geobotanical remote sensing, and data integration and geographic information systems. Particular attention is given to spectral alteration mapping with imaging spectrometers, mapping the coastal plain of the Congo with airborne digital radar, applications of remote sensing techniques to the assessment of dam safety, remote sensing of ferric iron minerals as guides for gold exploration, principal component analysis for alteration mappping, and the application of remote sensing techniques for gold prospecting in the north Fujian province.

  15. Hybrid image and signal processing II; Proceedings of the Meeting, Orlando, FL, Apr. 18-20, 1990

    SciTech Connect

    Casasent, D.P.; Tescher, A.G.

    1990-01-01

    The present conference discusses topics in the research fields of multisensor recognition and tracking, optical correlators and pattern recognition, optical processing applications, phase-only filters, digital signal processing techniques, and neural nets for image processing. Attention is given to multisensor data fusion for multitarget tracking, fast digital phase detection using SAWs, miniature hybrid optical correlators, shape representations by Gabor expansion, and a digital optoelectronic computer for textual pattern matching. Also discussed are feature detection and enhancement by a rotating kernel min-max transformation, a phase-phase implementation of optical correlators, the use of directional consistency with Sobel edge detectors, image-pattern algorithms using neural networks, assembly line inspection using neural networks, and image deconvolution by nonlinear techniques in the Fourier domain.

  16. Multichip modules; Proceedings of the 2nd International Conference and Exhibition, Denver, CO, Apr. 14-16, 1993

    NASA Astrophysics Data System (ADS)

    Consideration is given to multichip packaging in IBM; strength, ductility, and fatigue life of Al thin films; the evaluation of a multichip module (MCM) thermal design tool; using MCM technology to enhance the development of electronic control modules; the sequential process advantage in MCM-L construction; a novel solution for MCM-L utilizing surface laminar circuit and flip chip technology; development of a miniaturized MCM valve driver; and an elastomeric connector for MCM and test applications. Attention is also given to mixed wire bond, TAB, and flip chip interconnections on multilayer ceramic MCMs; advanced design and modeling for manufacturability of a hybrid package; multilevel thin film packaging technology at IBM; MCM applications for Hughes Military processors; regional competitive analysis of the global MCM industry infrastructure; and development and assembly of a 40 MHz MCM-L based DSP and fast static RAM MCM.

  17. Excrétion rénale des ions divalents après homotransplantation rénale

    PubMed Central

    Cartier, F.; Popovtzer, M. M.; Robinette, J.; Pinggera, W. F.; Halgrimson, C. G.; Starzl, T. E.

    2010-01-01

    RÉSUMÉ L’élimination rénale des ions divalents, celle du Na et du K, ont été étudiées de façon comparative dans les suites immédiates de l’homotransplantation rénale chez 6 patients. Durant la période initiale polyurique (> 3ml/mn), le taux d’excrétion du Ca filtré (Cca/Ccr), du Mg, du P, du Na et du K, est élevé et il existe une corrélation étroite et quasi constante entre l’élimination du Ca, du Mg et du Na ; la corrélation n’est pas constante entre l’élimination du Na et du K, du Mg et du K. Pendant les deux jours suivants, le taux d’excrétion diminue, sauf pour le P ; il existe encore une corrélation entre l’excrétion du Ca, du Mg et du Na, non entre celle du Na et du K, du Mg et du K. L’excrétion du Ca l’emporte sur celle du Na au cours de la première période, non au cours de la seconde. A la lumière de ces données, on envisage l’intervention possible de divers facteurs, tels l’inflation hydrosique et l’hyperazotémie préalables, l’ischémie rénale contemporaine de la transplantation, les effets de la dénervation rénale, du traitement cortisonique, de l’hyperparathyroïdie et ceux des modifications circulatoires rénales. PMID:4574592

  18. Examining interrater reliability and validity of a paediatric cardiopulmonary physiotherapy discharge tool.

    PubMed

    Lati, Jamil; Pellow, Vanessa; Sproule, Jeannine; Brooks, Dina; Ellerton, Cindy

    2014-01-01

    Objectif : Déterminer la fiabilité entre évaluateurs des six questions contenues dans le questionnaire sur le départ du service de physiothérapie cardiopulmonaire (PTC) pédiatrique qui détermine six éléments critiques dont les physiothérapeutes doivent tenir compte lorsqu'il s'agit de déterminer si un patient en pédiatrie est prêt à quitter le service de PTC après une chirurgie thoracique, cardiaque ou au haut de l'abdomen: saturation en oxygène, mobilité, rétention des sécrétions, préparation du départ, auscultation et signes de détresse respiratoire. Méthodes : Deux évaluateurs désignés ont évalué au total 33 patients en pédiatrie (âgés de 2 à <19 ans) qui ont reçu au moins une journée de PTC à la suite d'une chirurgie cardiaque, thoracique ou au haut de l'abdomen au moyen du questionnaire sur le départ du service de PTC pédiatrique. Les deux évaluateurs ont évalué chaque patient à moins de quatre heures d'intervalle. Résultats : Les six questions du questionnaire sur le départ du service de PTC pédiatrique ont révélé la convergence suivante à la suite d'une analyse kappa: saturation en oxygène, excellente (κ=0,80); mobilité, importante (κ=0,62); dégagement des sécrétions, modéré (κ=0,39); préparation du départ, moyenne (κ=0,37); et auscultation et détresse respiratoire, médiocre (κ=0,24 et κ=−0,08, respectivement). Conclusion : Plusieurs des questions du questionnaire sur le départ du service de PTC pédiatrique démontrent une bonne fiabilité entre évaluateurs. L'outil est prêt à soumettre à d'autres tests psychométriques et en particulier des tests de validité.

  19. Understanding approaches to balance assessment in physical therapy practice for elderly inpatients of a rehabilitation hospital.

    PubMed

    Gervais, Tanner; Burling, Nicole; Krull, Justin; Lugg, Carrie; Lung, Maria; Straus, Sharon; Jaglal, Susan; Sibley, Kathryn M

    2014-01-01

    Objectif : L'équilibre constitue un facteur modifiable critique de risque de chutes chez les adultes âgés. Cette étude visait à déterminer les outils utilisés en physiothérapie pour évaluer l'équilibre en pratique clinique et les éléments constituants de l'équilibre évalués au moyen de mesures normalisées ou autres. Méthodes : On a procédé à un examen rétrospectif des dossiers de 250 patients âgés de 65 ans et plus qui ont suivi une réadaptation en service interne après avoir reçu un diagnostic clinique associé à une déficience de l'équilibre (accident vasculaire cérébral, problèmes de l'appareil locomoteur, amputation d'un membre inférieur, déconditionnement et chirurgie cardiaque) à un hôpital de réadaptation de l'Ontario. Résultats : Tous les patients ont fait l'objet d'au moins une évaluation comportant un volet équilibre. On a pris des mesures normalisées de l'équilibre chez 73 % des patients : le test chronométré lever-marcher (48 %) et le test d'équilibre de Berg (36 %) ont servi le plus souvent pour cette évaluation. Les stratégies de mouvement réactifs et le traitement cognitif ont été les éléments de l'équilibre évalués le moins souvent. L'équilibre a été évalué le moins souvent chez les personnes qui avaient subi une chirurgie cardiaque. Conclusions : Il existe une variation importante au niveau de l'évaluation de l'équilibre et les données indiquent qu'il n'est pas tenu compte également de tous les éléments pertinents. Les recherches à venir dans d'autres contextes cliniques devraient inclure les évaluations d'autres professionnels de la santé afin de permettre de comprendre plus complètement les procédures actuelles d'évaluation de l'équilibre.

  20. La pubalgie du sportif: mise au point à propos d'une étude rétrospective de 128 joueurs

    PubMed Central

    Mahmoudi, Ammar; Frioui, Samia; Jemni, Sonia; Khachnaoui, Faycel; Dahmene, Younes

    2015-01-01

    La pubalgie du sportif de haut niveau représente une entité nosologique à part entière, tant en raison du mécanisme à l'origine de la pathologie que des lésions objectivables au niveau de la paroi abdominale. C'est un syndrome douloureux de la région inguino-pubienne qui touche particulièrement les footballeurs. Son étiologie est attribuée à la répétition de mouvements des membres inférieurs et du tronc associant rotation et adduction forcées. Son incidence est nettement plus élevée chez les hommes. Après avoir écarté une pathologie d'organe, le patient devrait bénéficier tout au début de son traitement conservateur d'une IRM afin d'effectuer un bilan lésionnel complet qui, selon les situations, permet d’écourter le traitement conservateur et de proposer un traitement chirurgical optimal. Le traitement doit être résolument conservateur pendant 3 mois. La rééducation est le plus souvent le traitement de première intention. Les patients présentant une persistance des symptômes sont candidats à la chirurgie. L'intervention de Nesovic est le traitement de choix chez les sportifs de haut niveau et qui permet, dans la très grande majorité des cas, une reprise sans aucune limitation de l'activité sportive antérieure. La technique de Bassini semble être moins lourde que celle de Nesovic, puisqu'elle est moins invasive. Une prise en charge multidisciplinaire centrée sur l'athlète avant et après l'intervention permet un retour aux activités physiques après quelques mois. Nous rapportons l'expérience de la prise en charge de 128 joueurs opérés selon la technique de Bassini et nous comparons nos résultats avec celles de la littérature. PMID:26966484

  1. Le dermatofibrosarcome de Darier et Ferrand, une tumeur cutanée particulière: à propos de 32 cas et revue de la littérature

    PubMed Central

    Elamrani, Driss; Droussi, Hatim; Boukind, Samira; Elatiqi, Keltoum; Dlimi, Meriem; Benchamkha, Yassine; Ettalbi, Saloua

    2014-01-01

    Le dermatofibrosarcome (DFS) est une tumeur fibreuse de la peau, de croissance lente, à très haut risque de récidive locale, mais à potentiel métastatique faible. A partir d'une étude rétrospective étalée sur une période de 5 ans (décembre 2008 - décembre 2013), nous avons analysé les caractéristiques épidémiologiques et cliniques, le délai de diagnostic, le type de thérapeutique et le devenir de 32 patients présentant des tumeurs de Darier et Ferrand histologiquement prouvées. Parmi les 32 patients, 10 se sont présentés initialement au service pour une récidive tumorale. Une discrète prédominance masculine a été notée. Les DFS touchent préférentiellement l'adulte jeune. Le délai diagnostique observé est en moyenne de 4 ans. Le tronc est la localisation préférentielle (60%), suivi par les extrémités proximales (30%). Les 32 patients ont été traités par exérèse chirurgicale avec une marge de 5cm en surface, emportant en profondeur une barrière anatomique saine. La couverture de la perte de substance (PDS) a été réalisée après confirmation anatomopathologique du caractère carcinologique de l'exérèse, et a fait appel à différents moyens allant de la greffe cutanée aux lambeaux musculo –cutanés libres. L’évolution a été marquée par la survenue d'une récidive tumorale chez 8 patients (3 cas parmi les tumeurs vues en première intention et 5 cas parmi les tumeurs vues en récidive) et les résultats ont été jugés satisfaisants sur le plan esthétique et fonctionnel. Le DFS de Darier et Ferrand est une tumeur dont le pronostic et le risque évolutif sont principalement liés au délai diagnostic et la qualité de la première exérèse. Le diagnostic tardif, rend difficile la chirurgie d'exérèse et de reconstruction Les possibilités de guérison en cas de chirurgie primaire bien conduite sont significativement supérieures à celles d'une chirurgie de rattrapage. L'amélioration du pronostic passe par

  2. La ténorraphie percutanée dans les ruptures fraîches du tendon calcanéen: à propos de 67 cas

    PubMed Central

    Bessam, Aman; Hassani, Zouhir Ameziane; Kharmaz, Mohamed; Steinmetz, Alain

    2014-01-01

    La rupture du tendon calcanéen est une des lésions les plus fréquentes en pathologie du sport, les deux options thérapeutiques classiques sont le traitement orthopédique et la chirurgie à ciel ouvert. Dans le but de minimiser ces complications, des techniques mini-invasives de ténorraphie percutanée ont été proposées dont les résultats sont encourageants. Il s'agit d'une étude rétrospective d'une série de cas de rupture sous cutanée du tendon d'Achille s’étalant de Avril 2005 au Juin 2012 concernant 67 patients; 11 femmes et 56 hommes avec un âge moyen de 41 ans. La cause principale était un accident de sport dans 45 cas. Le diagnostic était évident à l'examen chez tous les patients. Dans deux cas il s'agissait d'une rerupture survenant à 1 et 5 ans d'un traitement orthopédique. Dans un cas il s'agissait d'une rerupture survenant après une ténorraphie percutanée. Dans deux cas il s'agissait d'une rupture sur tendinopathie chronique. Tous les patients avaient bénéficié d'une radio de la cheville qui avait montré une horizontalisation du calcanéum chez 5 patients et surtout elle n'avait pas montré de fracture associée, alors que 15 patients avaient bénéficié d'une échographie qui a confirmé le diagnostic. Tous les patients avaient été opérés dans un délai de moins de 48 heures Une ténorraphie percutanée a été pratiqué chez tous les patients. Le recul moyen est de 43 mois, trois patients ont été perdus de vue Nous avons noté une reprise des activités professionnelle effective en moyen 90 jours après l'intervention et celle des activités sportive à 6 mois en moyenne L’état cutané local a été jugée bon dans 63 cas. Par ailleurs les complications ont été marquées par un seul cas d'infection ayant nécessité une reprise chirurgical a été noté mise à plat, trois cas de rerupture repris par suture à ciel ouvert, un cas d'algodystrophie et un cas de tendinopathie Il n'y a eu aucune complication

  3. Afflux massif de brûlés : la doctrine française de triage en temps de paix

    PubMed Central

    Bargues, L.; Fall, M.M.

    2015-01-01

    Summary Les situations de catastrophe impliquant un grand nombre de brûlés peuvent survenir à tout moment après un incendie, une attaque terroriste, une explosion industrielle ou un accident de transport. Les différentes sociétés internationales de brûlologie ont publié des recommandations sur la préparation à l’afflux massif de brûlés. La Société Française d’Étude et de Traitement des Brûlés (SFETB) propose le triage des victimes selon la Surface Cutanée Brûlée (SCB), l’inhalation de fumées et les lésions traumatiques associées. Ce plan cherche à catégoriser les victimes et à attribuer à chaque patient un lit adapté à ses besoins thérapeutiques (centre des brûlés, réanimation médicale ou chirurgicale, service d’urgences, chirurgie, poste de triage). Les Services d’Aide Médicale Urgente (SAMU) sont au coeur du dispositif : premiers soins, poste Médical Avancé (pMA), régulation, triage et transport, renfort en matériel dans l’hôpital de proximité. Un plan catastrophe pour brûlés doit être adapté aux capacités hospitalières du pays. PMID:26668563

  4. L'endométriose de la paroi abdominale: à propos d'un cas rare

    PubMed Central

    Jayi, Sofia; Laadioui, Meriem; Bouguern, Hakima; Chaara, Hikmat; Melhouf, Aabdelilah

    2013-01-01

    L'endométriose de la paroi est une entité clinique rare, dont la physiopathologie demeure imprécise. Elle survient le plus souvent après une intervention chirurgicale gynécologique ou obstétricale. Nous rapportons le cas d'une patiente présentant une douleur cyclique, au niveau de la cicatrice de césarienne. Avec à l'examen clinique une masse de 3 cm localisée au niveau de la fosse iliaque droite. L'échographie-doppler a objectivé une image d'allure tissulaire, polylobée, à vascularisation centrale, mesurant 32/16 mm, évoquent une masse endométriosique ou une tumeur des parties molles. D'où la décision d'excision de la lésion, au cours de laquelle on a découvert une masse dure de 3/2 cm, en sous aponévrotique accolée au muscle grand droit de l'abdomen. L'étude anatomopathologique a confirmé le diagnostic d'endométriose pariétale. Les suites postopératoires étaient simples avec un recul de 2 ans et demie sans récidive de la masse ni de la douleur. A travers notre cas, nous insisterons sur les caractéristiques de cette pathologie notamment pronostic, ce qui permettra au praticien de comprendre l'intérêt du diagnostic et prise en charge précoce de cette entité - pour laquelle on ne pense jamais assez devant une masse pariétale - et de sa prévention au cours de chaque chirurgie gynécologique ou obstétricale. PMID:24171068

  5. Schwannome benin primitif retrovesical: une tumeur très rare à propos d'un cas

    PubMed Central

    Beddouche, Ali; Fahsi, Othemane; Kallat, Adil; El Bote, Hicham; Ziani, Idriss; El Sayegh, Hachem; Iken, Ali; Benslimane, Lounis; Nouini, Yassine

    2016-01-01

    Le schwannome est une tumeur le plus souvent bénigne, d'origine nerveuse se développant à partir des cellules de la gaine de Schwann. C'est une tumeur très rare tant par sa fréquence que par sa localisation rétrovésicale. L'examen anatomopathologique et immunohistochimique confirme le type histologique ainsi que le caractère bénin ou malin du schwannome. En raison des récidives, et du risque de transformation maligne, l'exérèse doit être complète. Nous rapportons le cas d'un patient âgé de 39 ans, admis pour une douleur pelvienne chronique à type de pesanteur, des signes irritatifs du bas appareil urinaire, et des troubles de transit. L'imagerie (échographie, TDM, IRM) a révélé la présence d'une masse pelvienne rétrovésicale, à paroi fine, latéralisée à gauche, mesurant 68x70x70 mm, exerçant un effet de masse sur la vessie et le sigmoïde. L'intervention chirurgicale menée par une laparotomie médiane a permis l'exérèse d'une masse retrovésicale bien encapsulée. L'examen anatomopathologique et immunohistochimique ont conclu à un schwannome bénin. La récidive et la transformation maligne bien que rare après chirurgie impose une surveillance post opératoire clinique et tomodensitométrique annuelle. PMID:27217902

  6. Prise en charge et résultats fonctionnels des cataractes traumatiques dans la région centrale du Togo

    PubMed Central

    Saa, Kassoula Batomaguela Nonon; Maneh, Nidain; Vonor, Kokou; Banla, Mèba; Sounouvou, Ignace; Alaglo, Kossi; Balo, Komi Patrice

    2016-01-01

    Introduction La cataracte traumatique est une affection grave, car pouvant être à l’origine de la baisse visuelle partielle ou totale. Le but de notre travail a été d'apprécier les résultats fonctionnels post opératoires des cataractes traumatiques opérées dans la région Centrale du Togo. Méthodes Il s’agissait d’une étude rétrospective basée sur l’analyse des dossiers des patients ayant bénéficié d’une prise en charge chirurgicale pour cataracte traumatique en stratégie avancée et en poste fixe entre le 1er janvier 2009 et le 30 juin 2011. Résultats Sur un total de 1086 cas de cataracte opérés au cours cette période, 131 (12,06%) étaient d’origine traumatique. La moyenne d’âge était de 30,01 ±16,61 ans avec des extrêmes de 5 et 70 ans 85% des patients ont bénéficié d’une implantation avec 66% de bons et moyens résultats après correction au premier jour postopératoire selon la classification de l’OMS. Après deux mois de suivi, 85% des patients revus présentaient une acuité visuelle supérieure à 3/10. Conclusion Malgré les progrès de la micro chirurgie oculaire, celle de la cataracte traumatique demeure d’accès difficile à la fois pour le patient que pour le praticien surtout dans les pays en développement. Pour ces raisons la priorité doit être donnée à la prévention des traumatismes oculaires. PMID:28292070

  7. Plasmocytome solitaire osseux: expérience de l'institut national d'oncologie de Rabat (INO)

    PubMed Central

    Diakité, Adama; Nouni, Karima; Bellefqih, Sara; Kebdani, Tayeb; Benjaafar, Noureddine

    2014-01-01

    Nous évaluerons les aspects diagnostiques, thérapeutiques et évolutifs du plasmocytome solitaire osseux dans notre structure. Il s'agit d'une revue rétrospective portant sur 11 patients suivis et traités dans le Service de Radiothérapie de l'Institut National d'Oncologie de Rabat pour un plasmocytome solitaire osseux entre janvier 1999 et décembre 2009. L’âge moyen de nos patients était de 53 ans (19-79 ans). La douleur était le signe révélateur le plus fréquent. Le siège des lésions était rachidien dans 4cas, nasosinusien dans 2cas, orbitaire dans 1 cas, costal dans 1 cas, presternal dans 1 cas, sellaire dans 1 cas et sacré dans 1 cas. Tous les malades ont reçu une radiothérapie. Cette irradiation était délivrée seule dans 8 cas (73%) ou associée à la chirurgie (laminectomie) dans 3 cas (27%). La dose moyenne de la radiothérapie était de 44 Gy (30 à 60 Gy) et celle-ci a été délivrée par un appareil de télécobalthérapie ou un accélérateur linéaire. La durée moyenne de suivi était de 78 mois (38-118 mois). Le contrôle local, défini par une stabilité radiologique, a été obtenu chez 7 des 11 malades (87%). Un patient a évolué vers un myélome multiple après un délai de 8 mois. La radiothérapie constitue un traitement efficace du plasmocytome osseux solitaire. Le pronostic est affecté par l’évolution vers le myélome multiple, ce qui justifie une surveillance rigoureuse après traitement et suggère une réflexion sur la place exacte de la chimiothérapie. PMID:25392726

  8. Le mélanome malin: une tumeur rare des fosses nasales - à propos d'une série de 10 cas

    PubMed Central

    Errachdi, Amal; Epala, Brice Nkoua; Asabbane, Amal; Kabbali, Naoual; Hemmich, Mariem; Kebdani, Tayeb; Benjaafar, Noureddine

    2014-01-01

    Le mélanome malin des fosses nasales est une tumeur rare mais très agressive, de traitement complexe et de pronostic défavorable. Son traitement relève en principe d'une prise en charge essentiellement chirurgicale complétée par une radiothérapie. L'objectif de ce travail est de rapporter les caractéristiques cliniques, thérapeutiques et évolutives des mélanomes des fosses nasales. Nous avons analysé rétrospectivement 10 cas de mélanomes des fosses nasales suivis à l'institut national d'oncologie de Rabat. La rhinoscopie avec biopsie a permis la confirmation histologique du diagnostic de mélanome. Le bilan d'extension comprenait une tomodensitométrie ou imagerie par résonnance magnétique du massif facial, une radiographie thoracique et une échographie abdominale. Dans notre série, l’âge médian était de 67.5 ans, avec une prédominance féminine (7femmes et 3hommes). Le délai médian de découverte était de 6 mois. Deux patients étaient métastatiques d'emblée, et toutes les tumeurs étaient localement avancées au moment du diagnostic. Sept patients ont été opérés avec des limites chirurgicales envahies dans 2 cas et 3 patients étaient inopérables. 2 patients ont été irradiés après la chirurgie et 2 patients ont reçu une chimiothérapie arrêtée au moment de la progression. Deux patients ont récidivé après traitement, et un patient était en mauvais état général et a bénéficié uniquement de soins palliatifs. Tous les patients sont décédés avec un délai médian de survie de 12 mois. Le mélanome malin muqueux des fosses nasales, bien que rare, demeure une pathologie de pronostic défavorable et pose des problèmes de prise en charge. PMID:25404963

  9. L'intervention de Castaing dans le traitement chirurgical de l'instabilité chronique latérale de la cheville (à propos d'une série continue de 52 cas)

    PubMed Central

    Boukhris, Jalal; Mojib, Rifi; Mezghani, Sami; Jaeger, Jean Henri

    2014-01-01

    L'instabilité chronique de la cheville est l'une des évolutions possibles dans l'histoire naturelle de l'entorse aigüe de cheville. Elle représente 10% à 30% des séquelles d'entorses. Le traitement chirurgical est réservé aux patients ayant une instabilité de cheville persistante après rééducation à l'origine d'une gêne invalidante. La technique de ligamentoplastie utilisant le court fibulaire selon Castaing est la plus répondue en France. La simplicité du geste et ses bons résultats nous ont incités à poursuivre cette voie. Il s'agit d´une étude rétrospective à propos de 52 patients ayant bénéficié d'une ligamentoplastie au court fibulaire selon Castaing entre Janvier 2000 et Décembre 2010. Le recul minimum était d'un an. L’évaluation des patients reposait sur le score de Karlson et le “Ankle score” Molander et Olerud. Les patients sont satisfaits ou très satisfaits de l'intervention dans 80% des cas revus. Les résultats fonctionnels de nos patients sont comparables à ceux publiés dans la littérature. Le prélèvement du transplant du court fibulaire ne semble pas avoir de retentissement sur la stabilité de la cheville. Les patients conservent une éversion du pied satisfaisante avec une force comparable au côté opposé. L’évolution arthrosique de la cheville ne semble pas significative après cette chirurgie. Le point faible de notre étude est le nombre des patients perdus de vue, cela est lié à la jeunesse de la population opérée et au recrutement du service d'envergure nationale. PMID:25469182

  10. Applications of artificial intelligence 1993: Knowledge-based systems in aerospace and industry; Proceedings of the Meeting, Orlando, FL, Apr. 13-15, 1993

    NASA Technical Reports Server (NTRS)

    Fayyad, Usama M. (Editor); Uthurusamy, Ramasamy (Editor)

    1993-01-01

    The present volume on applications of artificial intelligence with regard to knowledge-based systems in aerospace and industry discusses machine learning and clustering, expert systems and optimization techniques, monitoring and diagnosis, and automated design and expert systems. Attention is given to the integration of AI reasoning systems and hardware description languages, care-based reasoning, knowledge, retrieval, and training systems, and scheduling and planning. Topics addressed include the preprocessing of remotely sensed data for efficient analysis and classification, autonomous agents as air combat simulation adversaries, intelligent data presentation for real-time spacecraft monitoring, and an integrated reasoner for diagnosis in satellite control. Also discussed are a knowledge-based system for the design of heat exchangers, reuse of design information for model-based diagnosis, automatic compilation of expert systems, and a case-based approach to handling aircraft malfunctions.

  11. 20 ans après: a second mutation in MAOA identified by targeted high-throughput sequencing in a family with altered behavior and cognition

    PubMed Central

    Piton, Amélie; Poquet, Hélène; Redin, Claire; Masurel, Alice; Lauer, Julia; Muller, Jean; Thevenon, Julien; Herenger, Yvan; Chancenotte, Sophie; Bonnet, Marlène; Pinoit, Jean-Michel; Huet, Frédéric; Thauvin-Robinet, Christel; Jaeger, Anne-Sophie; Le Gras, Stéphanie; Jost, Bernard; Gérard, Bénédicte; Peoc'h, Katell; Launay, Jean-Marie; Faivre, Laurence; Mandel, Jean-Louis

    2014-01-01

    Intellectual disability (ID) is characterized by an extraordinary genetic heterogeneity, with >250 genes that have been implicated in monogenic forms of ID. Because this complexity precluded systematic testing for mutations and because clinical features are often non-specific, for some of these genes only few cases or families have been unambiguously documented. It is the case of the X-linked gene encoding monoamine oxidase A (MAOA), for which only one nonsense mutation has been identified in Brunner syndrome, characterized in a single family by mild non-dysmorphic ID and impulsive, violent and aggressive behaviors. We have performed targeted high-throughput sequencing of 220 genes, including MAOA, in patients with undiagnosed ID. We identified a c.797_798delinsTT (p.C266F) missense mutation in MAOA in a boy with autism spectrum disorder, attention deficit and autoaggressive behavior. Two maternal uncles carry the mutation and have severe ID, with a history of maltreatment in early childhood. This novel missense mutation decreases MAOA enzymatic activity, leading to abnormal levels of urinary monoamines. The identification of this new point mutation confirms, for the first time since 1993, the monogenic implication of the MAOA gene in ID of various degrees, autism and behavioral disturbances. The variable expressivity of the mutation observed in male patients of this family may involve gene–environment interactions, and the identification of a perturbation in monoamine metabolism should be taken into account when prescribing psychoactive drugs in such patients. PMID:24169519

  12. 20 ans après: a second mutation in MAOA identified by targeted high-throughput sequencing in a family with altered behavior and cognition.

    PubMed

    Piton, Amélie; Poquet, Hélène; Redin, Claire; Masurel, Alice; Lauer, Julia; Muller, Jean; Thevenon, Julien; Herenger, Yvan; Chancenotte, Sophie; Bonnet, Marlène; Pinoit, Jean-Michel; Huet, Frédéric; Thauvin-Robinet, Christel; Jaeger, Anne-Sophie; Le Gras, Stéphanie; Jost, Bernard; Gérard, Bénédicte; Peoc'h, Katell; Launay, Jean-Marie; Faivre, Laurence; Mandel, Jean-Louis

    2014-06-01

    Intellectual disability (ID) is characterized by an extraordinary genetic heterogeneity, with >250 genes that have been implicated in monogenic forms of ID. Because this complexity precluded systematic testing for mutations and because clinical features are often non-specific, for some of these genes only few cases or families have been unambiguously documented. It is the case of the X-linked gene encoding monoamine oxidase A (MAOA), for which only one nonsense mutation has been identified in Brunner syndrome, characterized in a single family by mild non-dysmorphic ID and impulsive, violent and aggressive behaviors. We have performed targeted high-throughput sequencing of 220 genes, including MAOA, in patients with undiagnosed ID. We identified a c.797_798delinsTT (p.C266F) missense mutation in MAOA in a boy with autism spectrum disorder, attention deficit and autoaggressive behavior. Two maternal uncles carry the mutation and have severe ID, with a history of maltreatment in early childhood. This novel missense mutation decreases MAOA enzymatic activity, leading to abnormal levels of urinary monoamines. The identification of this new point mutation confirms, for the first time since 1993, the monogenic implication of the MAOA gene in ID of various degrees, autism and behavioral disturbances. The variable expressivity of the mutation observed in male patients of this family may involve gene-environment interactions, and the identification of a perturbation in monoamine metabolism should be taken into account when prescribing psychoactive drugs in such patients.

  13. PESC '88 - Annual IEEE Power Electronics Specialists Conference, 19th, Doshisha University, Kyoto, Japan, Apr. 11-14, 1988, Record. Volumes 1 & 2

    NASA Astrophysics Data System (ADS)

    Recent advances in electric-power conditioning techniques and devices are discussed in reviews and reports. Topics addressed include high-frequency resonant converters, control of inverters and converters, device simulation, magnetic energy storage, converter topologies, servo motor control, high-power converters, superconductive energy storage, machine control strategies, and power-electronics modeling and analysis. Consideration is given to analysis of power-train elements, vector control for induction motors, power conversion techniques, magnetic and capacitive components, harmonic and reactive power compensation, and inverter-converters for ac motor drives.

  14. Developments in theoretical and applied mechanics. Volume 14; Proceedings of the Fourteenth Southeastern Conference on Theoretical and Applied Mechanics, Biloxi, MS, Apr. 18, 19, 1988

    SciTech Connect

    Wang, S.S.Y.; Hackett, R.M.; Deleeuw, S.L.; Smith, A.M.

    1988-01-01

    The conference presents papers on computational fluid dynamics, coastal hydrodynamics, hydraulics, fluid mechanics, biomechanics, materials, structural mechanics, plates and shells, and numerical methods. Topics include unsteady transonic airfoil computation using implicit Euler scheme on body-fixed grid, the numerical simulation of the vertical flow over a round-edged double-delta wing, MHD modeling of solar active phenomena via numerical methods, and recent developments in turbulent flow. Consideration is also given to modeling of the dynamic sea surface with satellite altimeter signals, the wave structure in unsteady flows past a flat plate in a rotating medium, equivalent systems for variable stiffness plates, and higher order theories for thick transversely isotropic cylindrical shells.

  15. The effects of winglets on low aspect ratio wings at supersonic Mach numbers. M.S. Thesis Report Feb. 1989 - Apr. 1991

    NASA Technical Reports Server (NTRS)

    Keenan, James A.; Kuhlman, John M.

    1991-01-01

    A computational study was conducted on two wings, of aspect ratios 1.244 and 1.865, each having 65 degree leading edge sweep angles, to determine the effects of nonplanar winglets at supersonic Mach numbers. A Mach number of 1.62 was selected as the design value. The winglets studied were parametrically varied in alignment, length, sweep, camber, thickness, and dihedral angle to determine which geometry had the best predicted performance. For the computational analysis, an available Euler marching technique was used. The results indicated that the possibility existed for wing-winglet geometries to equal the performance of wing-alone bodies in supersonic flows with both bodies having the same semispan. The first wing with winglet used NACA 1402 airfoils for the base wing and was shown to have lift-to-pressure drag ratios within 0.136 percent to 0.360 percent of the NACA 1402 wing-alone. The other base wing was a natural flow wing which was previously designed specifically for a Mach number of 1.62. The results obtained showed that the natural wing-alone had a slightly higher lift-to-pressure drag than the natural wing with winglets.

  16. Monolithic microwave integrated circuits for sensors, radar, and communications systems; Proceedings of the Meeting, Orlando, FL, Apr. 2-4, 1991

    NASA Technical Reports Server (NTRS)

    Leonard, Regis F. (Editor); Bhasin, Kul B. (Editor)

    1991-01-01

    Consideration is given to MMICs for airborne phased arrays, monolithic GaAs integrated circuit millimeter wave imaging sensors, accurate design of multiport low-noise MMICs up to 20 GHz, an ultralinear low-noise amplifier technology for space communications, variable-gain MMIC module for space applications, a high-efficiency dual-band power amplifier for radar applications, a high-density circuit approach for low-cost MMIC circuits, coplanar SIMMWIC circuits, recent advances in monolithic phased arrays, and system-level integrated circuit development for phased-array antenna applications. Consideration is also given to performance enhancement in future communications satellites with MMIC technology insertion, application of Ka-band MMIC technology for an Orbiter/ACTS communications experiment, a space-based millimeter wave debris tracking radar, low-noise high-yield octave-band feedback amplifiers to 20 GHz, quasi-optical MESFET VCOs, and a high-dynamic-range mixer using novel balun structure.

  17. Étude des anomalies chromosomiques après radiothérapie chez des patients traités pour lymphome malin non-Hodgkinien

    NASA Astrophysics Data System (ADS)

    Mahe, M. A.; André, M. J.; Moyon, E.; Le Mevel, A.; Soubeyran, P.; Hamidou, M.; Milpied, N.; Bourdin, S.; Cuillière, J. C.; Chatal, J. F.

    1998-04-01

    Structural chromosome defects were evaluated in the lymphocytes of 30 patients (pts) who had undergone radiotherapy for non Hodgkin's lymphoma (NHL). Twelve had received 20 Grays (Gy) over the abdomen (group I), 12 whole body irradiation at 1.5 Gy (group II) and 6 whole body irradiation at 15 Gy (group III). A cohort of 468 unirradiated pts served as controls. For the irradiated group, 7% of cells had aberrations compared to 0.4% in controls {P <10-6}. The frequency of abnormal cells was statistically higher in group I (12%) than in group II (3.5%) and III (2.5%) . In group I, frequency of aberrations was statistically higher in pts who had additionnal extra-abdominal involved field irradiation, those with evolutive NHL and those receiving chemotherapy at the time of the cytogenetic analysis. Les aberrations chromosomiques ont ,été, mesurées sur les lymphocytes de 30 patients (pts) irradiés pour lymphome malin non-hodgkinien (LNH) selon 3 modalités : 20 Grays (Gy) sur l'abdomen (groupe I : 12 pts), Irradiation corporelle totale 1,5 Gy (groupe II : 12 pts), ou 15 Gy (groupe III : 6 pts). Une population non irradiée de 468 pts a servi de témoin. Dans le groupe irradié, 7 % des cellules présentaient des anomalies contre 0,4 % dans le groupe témoin {P <10-6}. Les aberrations ,étaient statistiquement plus nombreuses dans le groupe I (12 % des cellules) que dans les groupes II (3,5 %) et III (2,5 %). Dans le groupe I, les anomalies , étaient statistiquement plus fréquentes chez les pts ayant eu une irradiation localisée extra-abdominale en complément de celle de l'abdomen ainsi que chez ceux en rechute de leur LNH et ceux recevant une chimiothérapie lors de l',étude cytogénétique.

  18. Proceedings of the Symposium on Scanning Antennas (4th) held on 21-22 Apr 1952 at the Naval Research Laboratory, Washington, DC

    DTIC Science & Technology

    1952-07-18

    misstateöients are due to the shortcoming of the tränscripjion processes . :^ The success of this program required the efforts of many people, We are grateful to... process which was relatively inexpensive. The shaft which supported the Inner cone was purposely made hollo« to take ä s&vagulde feed line, The...fpcal; length then s»" = oc„ 0=-^«s>and|Mp^in| , - (is) RX iiMag .« .. _~*r. _ -5’rt> - -•*- 1« ,p""’ *•’ « SV-^JV

  19. AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics and Materials Conference, 33rd, Dallas, TX, Apr. 13-15, 1992, Technical Papers. Pt. 4 - Structural dynamics II

    SciTech Connect

    Not Available

    1992-01-01

    The present conference discusses composites damage tolerance, shell and cylinder buckling, computational structural mechanics, adaptive structures, structural risk and reliability, the analysis of composite structures, the thermal analysis of structures, the finite-element analysis of rotorcraft vibration, spacecraft dynamics, and rotor aeroelasticity. Also discussed are rotorcraft dynamics, structural damping, control analyses and control experiments, dynamic methods, experimental dynamics and testing, composite structural dynamics and damage, aeroelasticity, future directions in flight mechanics and structures, rotorcraft aeroelasticity, dynamics applications, unsteady aerodynamics, eigensolution methods, nonlinear dynamics, sensitivity analysis and topology optimization, shape optimization, modeling of material behavior, and ceramic-matrix composites.

  20. AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics and Materials Conference, 33rd, Dallas, TX, Apr. 13-15, 1992, Technical Papers. Pt. 3 - Structural dynamics I

    SciTech Connect

    Not Available

    1992-01-01

    The present conference on structural dynamics encompasses finite-element analyses of rotorcraft vibration, spacecraft dynamics, dynamic analyses, rotor aeroelasticity, rotorcraft dynamics, damping, control analysis and experiments, and experimental dynamics and testing. Specific issues addressed include NASA/industry design-analysis methods for vibrations, controlling a large flexible structure to mimic a rigid one, the dynamic response of rapidly heated space structures, interval prediction in structural dynamic analysis, mode localization in computer disk drives, and a discrete transfer-matrix method for rotating beams. Also addressed are the dynamics of axially moving continua on an elastic foundation, stiffness and stress in a fluid-filled circular diaphragm, linear structure control by the modal force technique, directional filters for sensing 1D structural dynamics, and an adaptive multilevel substructuring method for efficient modeling of complex structures.