Science.gov

Sample records for architecture based medical

  1. Medical nanorobot architecture based on nanobioelectronics.

    PubMed

    Cavalcanti, Adriano; Shirinzadeh, Bijan; Freitas, Robert A; Kretly, Luiz C

    2007-01-01

    This work describes an innovative medical nanorobot architecture based on important discoveries in nanotechnology, integrated circuit patents, and some publications, directly or indirectly related to one of the most challenging new fields of science: molecular machines. Thus, the architecture described in this paper reflects, and is supported by, some remarkable recent achievements and patents in nanoelectronics, wireless communication and power transmission techniques, nanotubes, lithography, biomedical instrumentation, genetics, and photonics. We also describe how medicine can benefit from the joint development of nanodevices which are derived, and which integrate techniques, from artificial intelligence, nanotechnology, and embedded smart sensors. Teleoperated surgical procedures, early disease diagnosis, and pervasive patient monitoring are some possible applications of nanorobots, reflecting progress along a roadmap for the gradual and practical development of nanorobots. To illustrate the described nanorobot architecture, a computational 3D approach with the application of nanorobots for diabetes is simulated using clinical data. Theoretical and practical analysis of system integration modeling is one important aspect for supporting the rapid development in the emerging field of nanotechnology. This provides useful directions for further research and development of medical nanorobotics and suggests a time frame in which nanorobots may be expected to be available for common utilization in therapeutic and medical procedures.

  2. Sensor-based architecture for medical imaging workflow analysis.

    PubMed

    Silva, Luís A Bastião; Campos, Samuel; Costa, Carlos; Oliveira, José Luis

    2014-08-01

    The growing use of computer systems in medical institutions has been generating a tremendous quantity of data. While these data have a critical role in assisting physicians in the clinical practice, the information that can be extracted goes far beyond this utilization. This article proposes a platform capable of assembling multiple data sources within a medical imaging laboratory, through a network of intelligent sensors. The proposed integration framework follows a SOA hybrid architecture based on an information sensor network, capable of collecting information from several sources in medical imaging laboratories. Currently, the system supports three types of sensors: DICOM repository meta-data, network workflows and examination reports. Each sensor is responsible for converting unstructured information from data sources into a common format that will then be semantically indexed in the framework engine. The platform was deployed in the Cardiology department of a central hospital, allowing identification of processes' characteristics and users' behaviours that were unknown before the utilization of this solution.

  3. [Wearable Medical Devices' MCU Selection Analysis Based on the ARM Cortex-MO+ Architecture].

    PubMed

    Wu, Zaoquan; Liu, Mengxing; Qin, Liping; Ye, Shuming; Chen, Hang

    2015-03-01

    According to the characteristics of low cost, high performance, high integration and long battery life of wearable medical devices, the mainstream low-power microcontroller(MCU) series were compared, and came to the conclusion that the MCU series based on ARM Cortex-M0+ architecture were suitable for the development of wearable medical devices. In aspects of power consumption, operational performance, integrated peripherals and cost, the MCU series based on Cortex-M0+ architecture of primary semiconductor companies were compared, aimed at providing the guides of MCU selection for wearable medical devices.

  4. [Development and application of a medical device maintenance information platform based on BS architecture].

    PubMed

    Liu, Shenglin; Zhang, Xutian; Wang, Guohong; Zhang, Qiang

    2012-03-01

    Based on specified demands on medical devices maintenance for clinical engineers and Browser/Server architecture technology, a medical device maintenance information platform was developed, which implemented the following modules such as repair, preventive maintenance, accessories management, training, document, system management and regional cooperation. The characteristics of this system were summarized and application in increase of repair efficiency, improvement of preventive maintenance and cost control was introduced. The application of this platform increases medical device maintenance service level.

  5. Next Generation RFID-Based Medical Service Management System Architecture in Wireless Sensor Network

    NASA Astrophysics Data System (ADS)

    Tolentino, Randy S.; Lee, Kijeong; Kim, Yong-Tae; Park, Gil-Cheol

    Radio Frequency Identification (RFID) and Wireless Sensor Network (WSN) are two important wireless technologies that have wide variety of applications and provide unlimited future potentials most especially in healthcare systems. RFID is used to detect presence and location of objects while WSN is used to sense and monitor the environment. Integrating RFID with WSN not only provides identity and location of an object but also provides information regarding the condition of the object carrying the sensors enabled RFID tag. However, there isn't any flexible and robust communication infrastructure to integrate these devices into an emergency care setting. An efficient wireless communication substrate for medical devices that addresses ad hoc or fixed network formation, naming and discovery, transmission efficiency of data, data security and authentication, as well as filtration and aggregation of vital sign data need to be study and analyze. This paper proposed an efficient next generation architecture for RFID-based medical service management system in WSN that possesses the essential elements of each future medical application that are integrated with existing medical practices and technologies in real-time, remote monitoring, in giving medication, and patient status tracking assisted by embedded wearable wireless sensors which are integrated in wireless sensor network.

  6. Toward a Fault Tolerant Architecture for Vital Medical-Based Wearable Computing.

    PubMed

    Abdali-Mohammadi, Fardin; Bajalan, Vahid; Fathi, Abdolhossein

    2015-12-01

    Advancements in computers and electronic technologies have led to the emergence of a new generation of efficient small intelligent systems. The products of such technologies might include Smartphones and wearable devices, which have attracted the attention of medical applications. These products are used less in critical medical applications because of their resource constraint and failure sensitivity. This is due to the fact that without safety considerations, small-integrated hardware will endanger patients' lives. Therefore, proposing some principals is required to construct wearable systems in healthcare so that the existing concerns are dealt with. Accordingly, this paper proposes an architecture for constructing wearable systems in critical medical applications. The proposed architecture is a three-tier one, supporting data flow from body sensors to cloud. The tiers of this architecture include wearable computers, mobile computing, and mobile cloud computing. One of the features of this architecture is its high possible fault tolerance due to the nature of its components. Moreover, the required protocols are presented to coordinate the components of this architecture. Finally, the reliability of this architecture is assessed by simulating the architecture and its components, and other aspects of the proposed architecture are discussed.

  7. Medical Data Architecture Project Status

    NASA Technical Reports Server (NTRS)

    Krihak, M.; Middour, C.; Lindsey, A.; Marker, N.; Wolfe, S.; Winther, S.; Ronzano, K.; Bolles, D.; Toscano, W.; Shaw, T.

    2017-01-01

    The Medical Data Architecture (MDA) project supports the Exploration Medical Capability (ExMC) risk to minimize or reduce the risk of adverse health outcomes and decrements in performance due to in-flight medical capabilities on human exploration missions. To mitigate this risk, the ExMC MDA project addresses the technical limitations identified in ExMC Gap Med 07: We do not have the capability to comprehensively process medically-relevant information to support medical operations during exploration missions. This gap identifies that the current International Space Station (ISS) medical data management includes a combination of data collection and distribution methods that are minimally integrated with on-board medical devices and systems. Furthermore, there are variety of data sources and methods of data collection. For an exploration mission, the seamless management of such data will enable an increasingly autonomous crew than the current ISS paradigm. The MDA will develop capabilities that support automated data collection, and the necessary functionality and challenges in executing a self-contained medical system that approaches crew health care delivery without assistance from ground support. To attain this goal, the first year of the MDA project focused on reducing technical risk, developing documentation and instituting iterative development processes that established the basis for the first version of MDA software (or Test Bed 1). Test Bed 1 is based on a nominal operations scenario authored by the ExMC Element Scientist. This narrative was decomposed into a Concept of Operations that formed the basis for Test Bed 1 requirements. These requirements were successfully vetted through the MDA Test Bed 1 System Requirements Review, which permitted the MDA project to begin software code development and component integration. This paper highlights the MDA objectives, development processes, and accomplishments, and identifies the fiscal year 2017 milestones and

  8. Nanorobot architecture for medical target identification

    NASA Astrophysics Data System (ADS)

    Cavalcanti, Adriano; Shirinzadeh, Bijan; Freitas, Robert A., Jr.; Hogg, Tad

    2008-01-01

    This work has an innovative approach for the development of nanorobots with sensors for medicine. The nanorobots operate in a virtual environment comparing random, thermal and chemical control techniques. The nanorobot architecture model has nanobioelectronics as the basis for manufacturing integrated system devices with embedded nanobiosensors and actuators, which facilitates its application for medical target identification and drug delivery. The nanorobot interaction with the described workspace shows how time actuation is improved based on sensor capabilities. Therefore, our work addresses the control and the architecture design for developing practical molecular machines. Advances in nanotechnology are enabling manufacturing nanosensors and actuators through nanobioelectronics and biologically inspired devices. Analysis of integrated system modeling is one important aspect for supporting nanotechnology in the fast development towards one of the most challenging new fields of science: molecular machines. The use of 3D simulation can provide interactive tools for addressing nanorobot choices on sensing, hardware architecture design, manufacturing approaches, and control methodology investigation.

  9. SW Architecture for Access to Medical Information for Knowledge Execution

    NASA Astrophysics Data System (ADS)

    Kim, Suntae; Shim, Bingu; Kim, Jeong Ah; Cho, Insook

    Recently, many approaches have been studied to author medical knowledge and verify doctor's diagnosis based on the specified knowledge. During the verification, intensive access to medical information is unavoidable. Also, the access approach should consider modifiability in order to cover diverse medical information from the variety of hospitals. This paper presents an approach to generating query language from medical knowledge, and shows software architecture for accessing medical information from hospitals by executing generated query languages. Implementation of this architecture has been deployed in a hospital of South Korea so that it shows the feasibility of the architecture.

  10. A Medical Image Backup Architecture Based on a NoSQL Database and Cloud Computing Services.

    PubMed

    Santos Simões de Almeida, Luan Henrique; Costa Oliveira, Marcelo

    2015-01-01

    The use of digital systems for storing medical images generates a huge volume of data. Digital images are commonly stored and managed on a Picture Archiving and Communication System (PACS), under the DICOM standard. However, PACS is limited because it is strongly dependent on the server's physical space. Alternatively, Cloud Computing arises as an extensive, low cost, and reconfigurable resource. However, medical images contain patient information that can not be made available in a public cloud. Therefore, a mechanism to anonymize these images is needed. This poster presents a solution for this issue by taking digital images from PACS, converting the information contained in each image file to a NoSQL database, and using cloud computing to store digital images.

  11. Medical Data Architecture Project Capabilities and Design

    NASA Technical Reports Server (NTRS)

    Middour, C.; Krihak, M.; Lindsey, A.; Marker, N.; Wolfe, S.; Winther, S.; Ronzano, K.; Bolles, D.; Toscano, W.; Shaw, T.

    2017-01-01

    Mission constraints will challenge the delivery of medical care on a long-term, deep space exploration mission. This type of mission will be restricted in the availability of medical knowledge, skills, procedures and resources to prevent, diagnose, and treat in-flight medical events. Challenges to providing medical care are anticipated, including resource and resupply constraints, delayed communications and no ability for medical evacuation. The Medical Data Architecture (MDA) project will enable medical care capability in this constrained environment. The first version of the system, called "Test Bed 1," includes capabilities for automated data collection, data storage and data retrieval to provide information to the Crew Medical Officer (CMO). Test Bed 1 seeks to establish a data architecture foundation and develop a scalable data management system through modular design and standardized interfaces. In addition, it will demonstrate to stakeholders the potential for an improved, automated, flow of data to and from the medical system over the current methods employed on the International Space Station (ISS). It integrates a set of external devices, software and processes, and a Subjective, Objective, Assessment, and Plan (SOAP) note commonly used by clinicians. Medical data like electrocardiogram plots, heart rate, skin temperature, respiration rate, medications taken, and more are collected from devices and stored in the Electronic Medical Records (EMR) system, and reported to crew and clinician. Devices integrated include the Astroskin biosensor vest and IMED CARDIAX electrocardiogram (ECG) device with INEED MD ECG Glove, and the NASA-developed Medical Dose Tracker application. The system is designed to be operated as a standalone system, and can be deployed in a variety of environments, from a laptop to a data center. The system is primarily composed of open-source software tools, and is designed to be modular, so new capabilities can be added. The software

  12. Medical image archive node simulation and architecture

    NASA Astrophysics Data System (ADS)

    Chiang, Ted T.; Tang, Yau-Kuo

    1996-05-01

    It is a well known fact that managed care and new treatment technologies are revolutionizing the health care provider world. Community Health Information Network and Computer-based Patient Record projects are underway throughout the United States. More and more hospitals are installing digital, `filmless' radiology (and other imagery) systems. They generate a staggering amount of information around the clock. For example, a typical 500-bed hospital might accumulate more than 5 terabytes of image data in a period of 30 years for conventional x-ray images and digital images such as Magnetic Resonance Imaging and Computer Tomography images. With several hospitals contributing to the archive, the storage required will be in the hundreds of terabytes. Systems for reliable, secure, and inexpensive storage and retrieval of digital medical information do not exist today. In this paper, we present a Medical Image Archive and Distribution Service (MIADS) concept. MIADS is a system shared by individual and community hospitals, laboratories, and doctors' offices that need to store and retrieve medical images. Due to the large volume and complexity of the data, as well as the diversified user access requirement, implementation of the MIADS will be a complex procedure. One of the key challenges to implementing a MIADS is to select a cost-effective, scalable system architecture to meet the ingest/retrieval performance requirements. We have performed an in-depth system engineering study, and developed a sophisticated simulation model to address this key challenge. This paper describes the overall system architecture based on our system engineering study and simulation results. In particular, we will emphasize system scalability and upgradability issues. Furthermore, we will discuss our simulation results in detail. The simulations study the ingest/retrieval performance requirements based on different system configurations and architectures for variables such as workload, tape

  13. A hospital information system based on Common Object Request Broker Architecture (CORBA) for exchanging distributed medical objects--an approach to future environment of sharing healthcare information.

    PubMed

    Ohe, K

    1998-01-01

    Tightly related subsystems in a HIS have to exchange medical data flexibly by the data object rather than by the battery of the data. We developed a CPR subsystem based on Common Object Request Broker Architecture (CORBA) that retrieves and stores clinical information in the object-oriented database via Internet Intra-ORB Protocol (IIOP). The system is hybridized with the legacy HIS applications on the client terminals. We believe that our solution and the experiences will contribute to the future CORBA-based environment in which computerized patient information is shared among hospitals, clinics, and tightly related systems.

  14. Nanorobot Hardware Architecture for Medical Defense.

    PubMed

    Cavalcanti, Adriano; Shirinzadeh, Bijan; Zhang, Mingjun; Kretly, Luiz C

    2008-05-06

    This work presents a new approach with details on the integrated platform and hardware architecture for nanorobots application in epidemic control, which should enable real time in vivo prognosis of biohazard infection. The recent developments in the field of nanoelectronics, with transducers progressively shrinking down to smaller sizes through nanotechnology and carbon nanotubes, are expected to result in innovative biomedical instrumentation possibilities, with new therapies and efficient diagnosis methodologies. The use of integrated systems, smart biosensors, and programmable nanodevices are advancing nanoelectronics, enabling the progressive research and development of molecular machines. It should provide high precision pervasive biomedical monitoring with real time data transmission. The use of nanobioelectronics as embedded systems is the natural pathway towards manufacturing methodology to achieve nanorobot applications out of laboratories sooner as possible. To demonstrate the practical application of medical nanorobotics, a 3D simulation based on clinical data addresses how to integrate communication with nanorobots using RFID, mobile phones, and satellites, applied to long distance ubiquitous surveillance and health monitoring for troops in conflict zones. Therefore, the current model can also be used to prevent and save a population against the case of some targeted epidemic disease.

  15. Nanorobot Hardware Architecture for Medical Defense

    PubMed Central

    Cavalcanti, Adriano; Shirinzadeh, Bijan; Zhang, Mingjun; Kretly, Luiz C.

    2008-01-01

    This work presents a new approach with details on the integrated platform and hardware architecture for nanorobots application in epidemic control, which should enable real time in vivo prognosis of biohazard infection. The recent developments in the field of nanoelectronics, with transducers progressively shrinking down to smaller sizes through nanotechnology and carbon nanotubes, are expected to result in innovative biomedical instrumentation possibilities, with new therapies and efficient diagnosis methodologies. The use of integrated systems, smart biosensors, and programmable nanodevices are advancing nanoelectronics, enabling the progressive research and development of molecular machines. It should provide high precision pervasive biomedical monitoring with real time data transmission. The use of nanobioelectronics as embedded systems is the natural pathway towards manufacturing methodology to achieve nanorobot applications out of laboratories sooner as possible. To demonstrate the practical application of medical nanorobotics, a 3D simulation based on clinical data addresses how to integrate communication with nanorobots using RFID, mobile phones, and satellites, applied to long distance ubiquitous surveillance and health monitoring for troops in conflict zones. Therefore, the current model can also be used to prevent and save a population against the case of some targeted epidemic disease. PMID:27879858

  16. Novel Architecture for supporting medical decision making of different data types based on Fuzzy Cognitive Map Framework.

    PubMed

    Papageorgiou, Elpiniki; Stylios, Chrysostomos; Groumpos, Peter

    2007-01-01

    Medical problems involve different types of variables and data, which have to be processed, analyzed and synthesized in order to reach a decision and/or conclude to a diagnosis. Usually, information and data set are both symbolic and numeric but most of the well-known data analysis methods deal with only one kind of data. Even when fuzzy approaches are considered, which are not depended on the scales of variables, usually only numeric data is considered. The medical decision support methods usually are accessed in only one type of available data. Thus, sophisticated methods have been proposed such as integrated hybrid learning approaches to process symbolic and numeric data for the decision support tasks. Fuzzy Cognitive Maps (FCM) is an efficient modelling method, which is based on human knowledge and experience and it can handle with uncertainty and it is constructed by extracted knowledge in the form of fuzzy rules. The FCM model can be enhanced if a fuzzy rule base (IF-THEN rules) is available. This rule base could be derived by a number of machine learning and knowledge extraction methods. Here it is introduced a hybrid attempt to handle situations with different types of available medical and/or clinical data and with difficulty to handle them for decision support tasks using soft computing techniques.

  17. An architecture for the construction of medical image databases

    NASA Astrophysics Data System (ADS)

    Marchaukoski, Jeroniza N.; Silva, Luciano; Sunye, Marcos S.; Bellon, Olga R. P.

    2003-05-01

    Due to the large volume and density of the medical images data, it is necessary the use of suitable database systems to facilitate their storage and management, interacting with the PACS (Picture Archiving and Communication Systems). This paper presents an architecture designed for acquisition and storage of the extracted data related to medical images, emphasizing the importance of experts in acquisition of consistent data. This work also presents the division of the information contained in the medical images into levels such as: low level, segmentation level, interpretation level, semantic level and related information. The levels work as a basis to the database schema represented by ER (entity relationship). This architecture has been validated by a content-based image retrieval system for Neonatology support.

  18. Flexible medical image management using service-oriented architecture.

    PubMed

    Shaham, Oded; Melament, Alex; Barak-Corren, Yuval; Kostirev, Igor; Shmueli, Noam; Peres, Yardena

    2012-01-01

    Management of medical images increasingly involves the need for integration with a variety of information systems. To address this need, we developed Content Management Offering (CMO), a platform for medical image management supporting interoperability through compliance with standards. CMO is based on the principles of service-oriented architecture, implemented with emphasis on three areas: clarity of business process definition, consolidation of service configuration management, and system scalability. Owing to the flexibility of this platform, a small team is able to accommodate requirements of customers varying in scale and in business needs. We describe two deployments of CMO, highlighting the platform's value to customers. CMO represents a flexible approach to medical image management, which can be applied to a variety of information technology challenges in healthcare and life sciences organizations.

  19. Blackboard architecture for medical image interpretation

    NASA Astrophysics Data System (ADS)

    Davis, Darryl N.; Taylor, Christopher J.

    1991-06-01

    There is a growing interest in using sophisticated knowledge-based systems for biomedical image interpretation. We present a principled attempt to use artificial intelligence methodologies in interpreting lateral skull x-ray images. Such radiographs are routinely used in cephalometric analysis to provide quantitative measurements useful to clinical orthodontists. Manual and interactive methods of analysis are known to be error prone and previous attempts to automate this analysis typically fail to capture the expertise and adaptability required to cope with the variability in biological structure and image quality. An integrated model-based system has been developed which makes use of a blackboard architecture and multiple knowledge sources. A model definition interface allows quantitative models, of feature appearance and location, to be built from examples as well as more qualitative modelling constructs. Visual task definition and blackboard control modules allow task-specific knowledge sources to act on information available to the blackboard in a hypothesise and test reasoning cycle. Further knowledge-based modules include object selection, location hypothesis, intelligent segmentation, and constraint propagation systems. Alternative solutions to given tasks are permitted.

  20. Architecture for Integrated Medical Model Dynamic Probabilistic Risk Assessment

    NASA Technical Reports Server (NTRS)

    Jaworske, D. A.; Myers, J. G.; Goodenow, D.; Young, M.; Arellano, J. D.

    2016-01-01

    Probabilistic Risk Assessment (PRA) is a modeling tool used to predict potential outcomes of a complex system based on a statistical understanding of many initiating events. Utilizing a Monte Carlo method, thousands of instances of the model are considered and outcomes are collected. PRA is considered static, utilizing probabilities alone to calculate outcomes. Dynamic Probabilistic Risk Assessment (dPRA) is an advanced concept where modeling predicts the outcomes of a complex system based not only on the probabilities of many initiating events, but also on a progression of dependencies brought about by progressing down a time line. Events are placed in a single time line, adding each event to a queue, as managed by a planner. Progression down the time line is guided by rules, as managed by a scheduler. The recently developed Integrated Medical Model (IMM) summarizes astronaut health as governed by the probabilities of medical events and mitigation strategies. Managing the software architecture process provides a systematic means of creating, documenting, and communicating a software design early in the development process. The software architecture process begins with establishing requirements and the design is then derived from the requirements.

  1. An Architecture for Continuous Data Quality Monitoring in Medical Centers.

    PubMed

    Endler, Gregor; Schwab, Peter K; Wahl, Andreas M; Tenschert, Johannes; Lenz, Richard

    2015-01-01

    In the medical domain, data quality is very important. Since requirements and data change frequently, continuous and sustainable monitoring and improvement of data quality is necessary. Working together with managers of medical centers, we developed an architecture for a data quality monitoring system. The architecture enables domain experts to adapt the system during runtime to match their specifications using a built-in rule system. It also allows arbitrarily complex analyses to be integrated into the monitoring cycle. We evaluate our architecture by matching its components to the well-known data quality methodology TDQM.

  2. Exploration Clinical Decision Support System: Medical Data Architecture

    NASA Technical Reports Server (NTRS)

    Lindsey, Tony; Shetye, Sandeep; Shaw, Tianna (Editor)

    2016-01-01

    The Exploration Clinical Decision Support (ECDS) System project is intended to enhance the Exploration Medical Capability (ExMC) Element for extended duration, deep-space mission planning in HRP. A major development guideline is the Risk of "Adverse Health Outcomes & Decrements in Performance due to Limitations of In-flight Medical Conditions". ECDS attempts to mitigate that Risk by providing crew-specific health information, actionable insight, crew guidance and advice based on computational algorithmic analysis. The availability of inflight health diagnostic computational methods has been identified as an essential capability for human exploration missions. Inflight electronic health data sources are often heterogeneous, and thus may be isolated or not examined as an aggregate whole. The ECDS System objective provides both a data architecture that collects and manages disparate health data, and an active knowledge system that analyzes health evidence to deliver case-specific advice. A single, cohesive space-ready decision support capability that considers all exploration clinical measurements is not commercially available at present. Hence, this Task is a newly coordinated development effort by which ECDS and its supporting data infrastructure will demonstrate the feasibility of intelligent data mining and predictive modeling as a biomedical diagnostic support mechanism on manned exploration missions. The initial step towards ground and flight demonstrations has been the research and development of both image and clinical text-based computer-aided patient diagnosis. Human anatomical images displaying abnormal/pathological features have been annotated using controlled terminology templates, marked-up, and then stored in compliance with the AIM standard. These images have been filtered and disease characterized based on machine learning of semantic and quantitative feature vectors. The next phase will evaluate disease treatment response via quantitative linear

  3. Space Elevator Base Leg Architecture

    NASA Astrophysics Data System (ADS)

    Swan, C.; Swan, P. A.

    While the Space Elevator stretches for 104,000 kilometers, the region of most concern, from the survival perspective, is 2,500 kms and below. The threats inside this dangerous arena include debris, spacecraft, meteorites, lightening, winds, rogue waves, aircraft, and intentional human acts. Two major questions will be addressed that will influence the overall systems architecture of a Space Elevator. While the deployment phase of the development of the Space Elevator will only have a single ribbon from the surface of the Earth to well beyond the Geosynchronous altitude, a mature Space Elevator must never allow a complete sever of the system. Design approaches, materials selections, international policy development and assembly must ensure that the integrity of the Space Elevator be maintained. The trade space analysis will address the probability of an individual ribbon being severed, the length of time to repair, and the potential for a catastrophic Space Elevator cut. The architecture proposed for the base leg portion will address two questions: Shall there be multiple base legs to 2,500 kms altitude? And Should the anchor be based on land or at sea?

  4. A patient-centric distribution architecture for medical image sharing.

    PubMed

    Constantinescu, Liviu; Kim, Jinman; Kumar, Ashnil; Haraguchi, Daiki; Wen, Lingfeng; Feng, Dagan

    2013-01-01

    Over the past decade, rapid development of imaging technologies has resulted in the introduction of improved imaging devices, such as multi-modality scanners that produce combined positron emission tomography-computed tomography (PET-CT) images. The adoption of picture archiving and communication systems (PACS) in hospitals have dramatically improved the ability to digitally share medical image studies via portable storage, mobile devices and the Internet. This has in turn led to increased productivity, greater flexibility, and improved communication between hospital staff, referring physicians, and outpatients. However, many of these sharing and viewing capabilities are limited to proprietary vendor-specific applications. Furthermore, there are still interoperability and deployment issues which reduce the rate of adoption of such technologies, thus leaving many stakeholders, particularly outpatients and referring physicians, with access to only traditional still images with no ability to view or interpret the data in full. In this paper, we present a distribution architecture for medical image display across numerous devices and media, which uses a preprocessor and an in-built networking framework to improve compatibility and promote greater accessibility of medical data. Our INVOLVE2 system consists of three main software modules: 1) a preprocessor, which collates and converts imaging studies into a compressed and distributable format; 2) a PACS-compatible workflow for self-managing distribution of medical data, e.g. via CD USB, network etc; 3) support for potential mobile and web-based data access. The focus of this study was on cultivating patient-centric care, by allowing outpatient users to comfortably access and interpret their own data. As such, the image viewing software included on our cross-platform CDs was designed with a simple and intuitive user-interface (UI) for use by outpatients and referring physicians. Furthermore, digital image access via

  5. International travel as medical research: architecture and the modern hospital.

    PubMed

    Logan, Cameron; Willis, Julie

    2010-01-01

    The design and development of the modern hospital in Australia had a profound impact on medical practice and research at a variety of levels. Between the late 1920s and the 1950s hospital architects, administrators, and politicians travelled widely in order to review the latest international developments in the hospital field They were motivated by Australia's geographic isolation and a growing concern with how to govern the population at the level of physical health. While not 'medical research' in the conventional sense of the term, this travel was a powerful generator of medical thinking in Australia and has left a rich archival legacy. This paper draws on that archive to demonstrate the ways in which architectural research and international networks of hospital specialists profoundly shaped the provision of medical infrastructure in Australia.

  6. Application of Multiprotocol Medical Imaging Communications and an Extended DICOM WADO Service in a Teleradiology Architecture

    PubMed Central

    Koutelakis, George V.; Anastassopoulos, George K.; Lymberopoulos, Dimitrios K.

    2012-01-01

    Multiprotocol medical imaging communication through the Internet is more flexible than the tight DICOM transfers. This paper introduces a modular multiprotocol teleradiology architecture that integrates DICOM and common Internet services (based on web, FTP, and E-mail) into a unique operational domain. The extended WADO service (a web extension of DICOM) and the other proposed services allow access to all levels of the DICOM information hierarchy as opposed to solely Object level. A lightweight client site is considered adequate, because the server site of the architecture provides clients with service interfaces through the web as well as invulnerable space for temporary storage, called as User Domains, so that users fulfill their applications' tasks. The proposed teleradiology architecture is pilot implemented using mainly Java-based technologies and is evaluated by engineers in collaboration with doctors. The new architecture ensures flexibility in access, user mobility, and enhanced data security. PMID:22489237

  7. Application of Multiprotocol Medical Imaging Communications and an Extended DICOM WADO Service in a Teleradiology Architecture.

    PubMed

    Koutelakis, George V; Anastassopoulos, George K; Lymberopoulos, Dimitrios K

    2012-01-01

    Multiprotocol medical imaging communication through the Internet is more flexible than the tight DICOM transfers. This paper introduces a modular multiprotocol teleradiology architecture that integrates DICOM and common Internet services (based on web, FTP, and E-mail) into a unique operational domain. The extended WADO service (a web extension of DICOM) and the other proposed services allow access to all levels of the DICOM information hierarchy as opposed to solely Object level. A lightweight client site is considered adequate, because the server site of the architecture provides clients with service interfaces through the web as well as invulnerable space for temporary storage, called as User Domains, so that users fulfill their applications' tasks. The proposed teleradiology architecture is pilot implemented using mainly Java-based technologies and is evaluated by engineers in collaboration with doctors. The new architecture ensures flexibility in access, user mobility, and enhanced data security.

  8. Medical Knowledge Bases.

    ERIC Educational Resources Information Center

    Miller, Randolph A.; Giuse, Nunzia B.

    1991-01-01

    Few commonly available, successful computer-based tools exist in medical informatics. Faculty expertise can be included in computer-based medical information systems. Computers allow dynamic recombination of knowledge to answer questions unanswerable with print textbooks. Such systems can also create stronger ties between academic and clinical…

  9. A fully programmable computing architecture for medical ultrasound machines.

    PubMed

    Schneider, Fabio Kurt; Agarwal, Anup; Yoo, Yang Mo; Fukuoka, Tetsuya; Kim, Yongmin

    2010-03-01

    Application-specific ICs have been traditionally used to support the high computational and data rate requirements in medical ultrasound systems, particularly in receive beamforming. Utilizing the previously developed efficient front-end algorithms, in this paper, we present a simple programmable computing architecture, consisting of a field-programmable gate array (FPGA) and a digital signal processor (DSP), to support core ultrasound signal processing. It was found that 97.3% and 51.8% of the FPGA and DSP resources are, respectively, needed to support all the front-end and back-end processing for B-mode imaging with 64 channels and 120 scanlines per frame at 30 frames/s. These results indicate that this programmable architecture can meet the requirements of low- and medium-level ultrasound machines while providing a flexible platform for supporting the development and deployment of new algorithms and emerging clinical applications.

  10. Entropy-based consistent model driven architecture

    NASA Astrophysics Data System (ADS)

    Niepostyn, Stanisław Jerzy

    2016-09-01

    A description of software architecture is a plan of the IT system construction, therefore any architecture gaps affect the overall success of an entire project. The definitions mostly describe software architecture as a set of views which are mutually unrelated, hence potentially inconsistent. Software architecture completeness is also often described in an ambiguous way. As a result most methods of IT systems building comprise many gaps and ambiguities, thus presenting obstacles for software building automation. In this article the consistency and completeness of software architecture are mathematically defined based on calculation of entropy of the architecture description. Following this approach, in this paper we also propose our method of automatic verification of consistency and completeness of the software architecture development method presented in our previous article as Consistent Model Driven Architecture (CMDA). The proposed FBS (Functionality-Behaviour-Structure) entropy-based metric applied in our CMDA approach enables IT architects to decide whether the modelling process is complete and consistent. With this metric, software architects could assess the readiness of undergoing modelling work for the start of IT system building. It even allows them to assess objectively whether the designed software architecture of the IT system could be implemented at all. The overall benefit of such an approach is that it facilitates the preparation of complete and consistent software architecture more effectively as well as it enables assessing and monitoring of the ongoing modelling development status. We demonstrate this with a few industry examples of IT system designs.

  11. New chiral cyclooctatriene-based polycyclic architectures.

    PubMed

    Pieters, Grégory; Gaucher, Anne; Marrot, Jérôme; Maurel, François; Naubron, Jean-Valère; Jean, Marion; Vanthuyne, Nicolas; Crassous, Jeanne; Prim, Damien

    2011-08-19

    The synthesis and properties of new chiral polycyclic architectures that display both helicity and a saddle-type shape are described. The enantiomers have been separated, and their absolute configuration was determined by VCD and ECD. The unprecedented molecular architecture is based on a cyclooctatriene core surrounded by an association of benzo[c]fluorene and ortho-phenylene units.

  12. Options for a lunar base surface architecture

    NASA Technical Reports Server (NTRS)

    Roberts, Barney B.

    1991-01-01

    The analysis of the Space Exploration Initiative architectures involves making definitions of systems engineering designs for the construction of lunar and Mars bases for the support of science, exploration, and resource production on these planets. This paper discusses the results of the Space Resource Utilization Architecture study, which was initiated to develop the technical capability for extracting useful materials from the indigenous resources of the moon and Mars. For the moon, an infrastructure concept of a base is designed which can support a crew of 12. The major phases of the lunar-base development, the systems and the elements involved, and the physical layout and evolution of the base are described.

  13. An architecture for rule based system explanation

    NASA Technical Reports Server (NTRS)

    Fennel, T. R.; Johannes, James D.

    1990-01-01

    A system architecture is presented which incorporate both graphics and text into explanations provided by rule based expert systems. This architecture facilitates explanation of the knowledge base content, the control strategies employed by the system, and the conclusions made by the system. The suggested approach combines hypermedia and inference engine capabilities. Advantages include: closer integration of user interface, explanation system, and knowledge base; the ability to embed links to deeper knowledge underlying the compiled knowledge used in the knowledge base; and allowing for more direct control of explanation depth and duration by the user. User models are suggested to control the type, amount, and order of information presented.

  14. ITOHealth: a multimodal middleware-oriented integrated architecture for discovering medical entities.

    PubMed

    Alor-Hernández, Giner; Sánchez-Cervantes, José Luis; Juárez-Martínez, Ulises; Posada-Gómez, Rubén; Cortes-Robles, Guillermo; Aguilar-Laserre, Alberto

    2012-03-01

    Emergency healthcare is one of the emerging application domains for information services, which requires highly multimodal information services. The time of consuming pre-hospital emergency process is critical. Therefore, the minimization of required time for providing primary care and consultation to patients is one of the crucial factors when trying to improve the healthcare delivery in emergency situations. In this sense, dynamic location of medical entities is a complex process that needs time and it can be critical when a person requires medical attention. This work presents a multimodal location-based system for locating and assigning medical entities called ITOHealth. ITOHealth provides a multimodal middleware-oriented integrated architecture using a service-oriented architecture in order to provide information of medical entities in mobile devices and web browsers with enriched interfaces providing multimodality support. ITOHealth's multimodality is based on the use of Microsoft Agent Characters, the integration of natural language voice to the characters, and multi-language and multi-characters support providing an advantage for users with visual impairments.

  15. An Architecture for Case-Based Learning

    ERIC Educational Resources Information Center

    Cifuentes, Laurent; Mercer, Rene; Alverez, Omar; Bettati, Riccardo

    2010-01-01

    We report on the design, development, implementation, and evaluation of a case-based instructional environment designed for learning network engineering skills for cybersecurity. We describe the societal problem addressed, the theory-based solution, and the preliminary testing and evaluation of that solution. We identify an architecture for…

  16. Design considerations of CareWindows, a Windows 3.0-based graphical front end to a Medical Information Management System using a pass-through-requester architecture.

    PubMed Central

    Ward, R. E.; Purves, T.; Feldman, M.; Schiffman, R. M.; Barry, S.; Christner, M.; Kipa, G.; McCarthy, B. D.; Stiphout, R.

    1991-01-01

    The Care Windows development project demonstrated the feasibility of an approach designed to add the benefits of an event-driven, graphically-oriented user interface to an existing Medical Information Management System (MIMS) without overstepping economic and logistic constraints. The design solution selected for the Care Windows project incorporates three important design features: (1) the effective de-coupling of severs from requesters, permitting the use of an extensive pre-existing library of MIMS servers, (2) the off-loading of program control functions of the requesters to the workstation processor, reducing the load per transaction on central resources and permitting the use of object-oriented development environments available for microcomputers, (3) the selection of a low end, GUI-capable workstation consisting of a PC-compatible personal computer running Microsoft Windows 3.0, and (4) the development of a highly layered, modular workstation application, permitting the development of interchangeable modules to insure portability and adaptability. PMID:1807665

  17. Computer-Based Medical System

    NASA Technical Reports Server (NTRS)

    1998-01-01

    SYMED, Inc., developed a unique electronic medical records and information management system. The S2000 Medical Interactive Care System (MICS) incorporates both a comprehensive and interactive medical care support capability and an extensive array of digital medical reference materials in either text or high resolution graphic form. The system was designed, in cooperation with NASA, to improve the effectiveness and efficiency of physician practices. The S2000 is a MS (Microsoft) Windows based software product which combines electronic forms, medical documents, records management, and features a comprehensive medical information system for medical diagnostic support and treatment. SYMED, Inc. offers access to its medical systems to all companies seeking competitive advantages.

  18. Cloud-based Architecture Capabilities Summary Report

    SciTech Connect

    Vang, Leng; Prescott, Steven R; Smith, Curtis

    2014-09-01

    In collaborating scientific research arena it is important to have an environment where analysts have access to a shared of information documents, software tools and be able to accurately maintain and track historical changes in models. A new cloud-based environment would be accessible remotely from anywhere regardless of computing platforms given that the platform has available of Internet access and proper browser capabilities. Information stored at this environment would be restricted based on user assigned credentials. This report reviews development of a Cloud-based Architecture Capabilities (CAC) as a web portal for PRA tools.

  19. Low Power Adder Based Auditory Filter Architecture

    PubMed Central

    Jayanthi, V. S.

    2014-01-01

    Cochlea devices are powered up with the help of batteries and they should possess long working life to avoid replacing of devices at regular interval of years. Hence the devices with low power consumptions are required. In cochlea devices there are numerous filters, each responsible for frequency variant signals, which helps in identifying speech signals of different audible range. In this paper, multiplierless lookup table (LUT) based auditory filter is implemented. Power aware adder architectures are utilized to add the output samples of the LUT, available at every clock cycle. The design is developed and modeled using Verilog HDL, simulated using Mentor Graphics Model-Sim Simulator, and synthesized using Synopsys Design Compiler tool. The design was mapped to TSMC 65 nm technological node. The standard ASIC design methodology has been adapted to carry out the power analysis. The proposed FIR filter architecture has reduced the leakage power by 15% and increased its performance by 2.76%. PMID:25506073

  20. Low power adder based auditory filter architecture.

    PubMed

    Rahiman, P F Khaleelur; Jayanthi, V S

    2014-01-01

    Cochlea devices are powered up with the help of batteries and they should possess long working life to avoid replacing of devices at regular interval of years. Hence the devices with low power consumptions are required. In cochlea devices there are numerous filters, each responsible for frequency variant signals, which helps in identifying speech signals of different audible range. In this paper, multiplierless lookup table (LUT) based auditory filter is implemented. Power aware adder architectures are utilized to add the output samples of the LUT, available at every clock cycle. The design is developed and modeled using Verilog HDL, simulated using Mentor Graphics Model-Sim Simulator, and synthesized using Synopsys Design Compiler tool. The design was mapped to TSMC 65 nm technological node. The standard ASIC design methodology has been adapted to carry out the power analysis. The proposed FIR filter architecture has reduced the leakage power by 15% and increased its performance by 2.76%.

  1. Options for a lunar base surface architecture

    NASA Technical Reports Server (NTRS)

    Roberts, Barney B.

    1992-01-01

    The Planet Surface Systems Office at the NASA Johnson Space Center has participated in an analysis of the Space Exploration Initiative architectures described in the Synthesis Group report. This effort involves a Systems Engineering and Integration effort to define point designs for evolving lunar and Mars bases that support substantial science, exploration, and resource production objectives. The analysis addresses systems-level designs; element requirements and conceptual designs; assessments of precursor and technology needs; and overall programmatics and schedules. This paper focuses on the results of the study of the Space Resource Utilization Architecture. This architecture develops the capability to extract useful materials from the indigenous resources of the Moon and Mars. On the Moon, a substantial infrastructure is emplaced which can support a crew of up to twelve. Two major process lines are developed: one produces oxygen, ceramics, and metals; the other produces hydrogen, helium, and other volatiles. The Moon is also used for a simulation of a Mars mission. Significant science capabilities are established in conjunction with resource development. Exploration includes remote global surveys and piloted sorties of local and regional areas. Science accommodations include planetary science, astronomy, and biomedical research. Greenhouses are established to provide a substantial amount of food needs.

  2. Options for a lunar base surface architecture

    NASA Astrophysics Data System (ADS)

    Roberts, Barney B.

    1992-02-01

    The Planet Surface Systems Office at the NASA Johnson Space Center has participated in an analysis of the Space Exploration Initiative architectures described in the Synthesis Group report. This effort involves a Systems Engineering and Integration effort to define point designs for evolving lunar and Mars bases that support substantial science, exploration, and resource production objectives. The analysis addresses systems-level designs; element requirements and conceptual designs; assessments of precursor and technology needs; and overall programmatics and schedules. This paper focuses on the results of the study of the Space Resource Utilization Architecture. This architecture develops the capability to extract useful materials from the indigenous resources of the Moon and Mars. On the Moon, a substantial infrastructure is emplaced which can support a crew of up to twelve. Two major process lines are developed: one produces oxygen, ceramics, and metals; the other produces hydrogen, helium, and other volatiles. The Moon is also used for a simulation of a Mars mission. Significant science capabilities are established in conjunction with resource development. Exploration includes remote global surveys and piloted sorties of local and regional areas. Science accommodations include planetary science, astronomy, and biomedical research. Greenhouses are established to provide a substantial amount of food needs.

  3. An Analysis of an Improved Bus-Based Multiprocessor Architecture

    NASA Technical Reports Server (NTRS)

    Ricks, Kenneth G.; Wells, B. Earl

    1998-01-01

    This paper analyses the effectiveness of a hybrid multiprocessing/multicomputing architecture that is based upon a single-board-computer multiprocessor (SBCM) architecture. Based upon empirical analysis using discrete event simulations and Monte Carlo techniques, this hybrid architecture, called the enhanced single-board-computer multiprocessor (ESBCM), is shown to have improved performance and scalability characteristics over current SBCM designs.

  4. A High Performance COTS Based Computer Architecture

    NASA Astrophysics Data System (ADS)

    Patte, Mathieu; Grimoldi, Raoul; Trautner, Roland

    2014-08-01

    Using Commercial Off The Shelf (COTS) electronic components for space applications is a long standing idea. Indeed the difference in processing performance and energy efficiency between radiation hardened components and COTS components is so important that COTS components are very attractive for use in mass and power constrained systems. However using COTS components in space is not straightforward as one must account with the effects of the space environment on the COTS components behavior. In the frame of the ESA funded activity called High Performance COTS Based Computer, Airbus Defense and Space and its subcontractor OHB CGS have developed and prototyped a versatile COTS based architecture for high performance processing. The rest of the paper is organized as follows: in a first section we will start by recapitulating the interests and constraints of using COTS components for space applications; then we will briefly describe existing fault mitigation architectures and present our solution for fault mitigation based on a component called the SmartIO; in the last part of the paper we will describe the prototyping activities executed during the HiP CBC project.

  5. Hybrid Power Management-Based Vehicle Architecture

    NASA Technical Reports Server (NTRS)

    Eichenberg, Dennis J.

    2011-01-01

    Hybrid Power Management (HPM) is the integration of diverse, state-of-the-art power devices in an optimal configuration for space and terrestrial applications (s ee figure). The appropriate application and control of the various power devices significantly improves overall system performance and efficiency. The basic vehicle architecture consists of a primary power source, and possibly other power sources, that provides all power to a common energy storage system that is used to power the drive motors and vehicle accessory systems. This architecture also provides power as an emergency power system. Each component is independent, permitting it to be optimized for its intended purpose. The key element of HPM is the energy storage system. All generated power is sent to the energy storage system, and all loads derive their power from that system. This can significantly reduce the power requirement of the primary power source, while increasing the vehicle reliability. Ultracapacitors are ideal for an HPM-based energy storage system due to their exceptionally long cycle life, high reliability, high efficiency, high power density, and excellent low-temperature performance. Multiple power sources and multiple loads are easily incorporated into an HPM-based vehicle. A gas turbine is a good primary power source because of its high efficiency, high power density, long life, high reliability, and ability to operate on a wide range of fuels. An HPM controller maintains optimal control over each vehicle component. This flexible operating system can be applied to all vehicles to considerably improve vehicle efficiency, reliability, safety, security, and performance. The HPM-based vehicle architecture has many advantages over conventional vehicle architectures. Ultracapacitors have a much longer cycle life than batteries, which greatly improves system reliability, reduces life-of-system costs, and reduces environmental impact as ultracapacitors will probably never need to be

  6. MEDEMAS -Medical Device Management and Maintenance System Architecture

    NASA Astrophysics Data System (ADS)

    Dogan, Ülkü Balcı; Dogan, Mehmet Ugur; Ülgen, Yekta; Özkan, Mehmed

    In the proposed study, a medical device maintenance management system (MEDEMAS) is designed and implemented which provides a data pool of medical devices, the maintenance protocols and other required information for these devices. The system also contains complete repair and maintenance history of a specific device. MEDEMAS creates optimal maintenance schedule for devices and enables the service technician to carry out and report maintenance/repair processes via remote access. Thus predicted future failures are possible to prevent or minimize. Maintenance and repair is essential for patient safety and proper functioning of the medical devices, as it prevents performance decrease of the devices, deterioration of the equipment, and detrimental effects on the health of a patient, the user or other interacting people. The study aims to make the maintenance process more accurate, more efficient, faster and easier to manage and organize; and much less confusing. The accumulated history of medical devices and maintenance personnel helps efficient facility planning.

  7. Efficient 3-D medical image registration using a distributed blackboard architecture.

    PubMed

    Tait, Roger J; Schaefer, Gerald; Hopgood, Adrian A; Zhu, Shao Ying

    2006-01-01

    A major drawback of 3-D medical image registration techniques is the performance bottleneck associated with re-sampling and similarity computation. Such bottlenecks limit registration applications in clinical situations where fast execution times are required and become particularly apparent in the case of registering 3-D data sets. In this paper a novel framework for high performance intensity-based volume registration is presented. Geometric alignment of both reference and sensed volume sets is achieved through a combination of scaling, translation, and rotation. Crucially, resampling and similarity computation is performed intelligently by a set of knowledge sources. The knowledge sources work in parallel and communicate with each other by means of a distributed blackboard architecture. Partitioning of the blackboard is used to balance communication and processing workloads. Large-scale registrations with substantial speedups, when compared with a conventional implementation, have been demonstrated.

  8. Domain tree-based analysis of protein architecture evolution.

    PubMed

    Forslund, Kristoffer; Henricson, Anna; Hollich, Volker; Sonnhammer, Erik L L

    2008-02-01

    Understanding the dynamics behind domain architecture evolution is of great importance to unravel the functions of proteins. Complex architectures have been created throughout evolution by rearrangement and duplication events. An interesting question is how many times a particular architecture has been created, a form of convergent evolution or domain architecture reinvention. Previous studies have approached this issue by comparing architectures found in different species. We wanted to achieve a finer-grained analysis by reconstructing protein architectures on complete domain trees. The prevalence of domain architecture reinvention in 96 genomes was investigated with a novel domain tree-based method that uses maximum parsimony for inferring ancestral protein architectures. Domain architectures were taken from Pfam. To ensure robustness, we applied the method to bootstrap trees and only considered results with strong statistical support. We detected multiple origins for 12.4% of the scored architectures. In a much smaller data set, the subset of completely domain-assigned proteins, the figure was 5.6%. These results indicate that domain architecture reinvention is a much more common phenomenon than previously thought. We also determined which domains are most frequent in multiply created architectures and assessed whether specific functions could be attributed to them. However, no strong functional bias was found in architectures with multiple origins.

  9. High-dynamic-range pixel architectures for diagnostic medical imaging

    NASA Astrophysics Data System (ADS)

    Karim, Karim S.; Yin, Sherman; Nathan, Arokia; Rowlands, John A.

    2004-05-01

    One approach to increase pixel signal-to-noise ratio (SNR) in low noise digital fluoroscopy is to employ in-situ pixel amplification via current-mediated active pixel sensors (C-APS). Experiments reveal a reduction in readout noise and indicate that an a-Si C-APS, coupled together with an established X-ray detection technology such as amorphous selenium (a-Se), can meet the stringent requirements (of < 1000 noise electrons) for digital X-ray fluoroscopy. A challenge with the C-APS circuit is the presence of a small-signal input linearity constraint. While using such a pixel amplifier for real-time fluoroscopy (where the exposure level is small) is feasible, the voltage change at the amplifier input is much higher in chest radiography or mammography due to the larger X-ray exposure levels. The larger input voltage causes the C-APS output to be non-linear thus reducing the pixel dynamic range. In addition, the resulting larger pixel output current causes the external column amplifier to saturate further reducing the pixel dynamic range. In this research, we investigate two alternate amplified pixel architectures that exhibit higher dynamic range. The test pixels are designed and simulated using an a-Si TFT model implemented in Verilog-A and results indicate a linear performance, high dynamic range, and a programmable circuit gain via choice of supply voltage and sampling time. These high dynamic range pixel architectures have the potential to enable a large area, active matrix flat panel imager (AMFPI) to switch instantly between low exposure, fluoroscopic imaging and higher exposure radiographic imaging modes. Lastly, the high dynamic range pixel circuits are suitable for integration with on-panel multiplexers for both gate and data lines, which can further reduce circuit complexity.

  10. Web based aphasia test using service oriented architecture (SOA)

    NASA Astrophysics Data System (ADS)

    Voos, J. A.; Vigliecca, N. S.; Gonzalez, E. A.

    2007-11-01

    Based on an aphasia test for Spanish speakers which analyze the patient's basic resources of verbal communication, a web-enabled software was developed to automate its execution. A clinical database was designed as a complement, in order to evaluate the antecedents (risk factors, pharmacological and medical backgrounds, neurological or psychiatric symptoms, brain injury -anatomical and physiological characteristics, etc) which are necessary to carry out a multi-factor statistical analysis in different samples of patients. The automated test was developed following service oriented architecture and implemented in a web site which contains a tests suite, which would allow both integrating the aphasia test with other neuropsychological instruments and increasing the available site information for scientific research. The test design, the database and the study of its psychometric properties (validity, reliability and objectivity) were made in conjunction with neuropsychological researchers, who participate actively in the software design, based on the patients or other subjects of investigation feedback.

  11. Web-based medical image archive system

    NASA Astrophysics Data System (ADS)

    Suh, Edward B.; Warach, Steven; Cheung, Huey; Wang, Shaohua A.; Tangiral, Phanidral; Luby, Marie; Martino, Robert L.

    2002-05-01

    This paper presents a Web-based medical image archive system in three-tier, client-server architecture for the storage and retrieval of medical image data, as well as patient information and clinical data. The Web-based medical image archive system was designed to meet the need of the National Institute of Neurological Disorders and Stroke for a central image repository to address questions of stroke pathophysiology and imaging biomarkers in stroke clinical trials by analyzing images obtained from a large number of clinical trials conducted by government, academic and pharmaceutical industry researchers. In the database management-tier, we designed the image storage hierarchy to accommodate large binary image data files that the database software can access in parallel. In the middle-tier, a commercial Enterprise Java Bean server and secure Web server manages user access to the image database system. User-friendly Web-interfaces and applet tools are provided in the client-tier for easy access to the image archive system over the Internet. Benchmark test results show that our three-tier image archive system yields fast system response time for uploading, downloading, and querying the image database.

  12. The architecture of evidence-based gynaecology.

    PubMed

    Khan, Khalid S

    2006-10-01

    Modern evidence-based medicine (EBM) and its predecessor 'Medecin d'Observation' both emphasise that potential advances in healthcare must be researched and proven to do more good than harm using the principles of clinical epidemiology before they are incorporated into medical practice. EBM is considered an important advance in improving clinical care in gynaecology but EBM skills have traditionally not been covered in undergraduate or postgraduate education. Therefore there is a perceived need to compile texts on various aspects of gynaecological practice using EBM principles. This is what these two issues of the Best Practice series hope to achieve. The various chapters will provide readers with clinical advice generated from critically appraised information that has been identified as addressing relevant questions.

  13. Citizen Observatories: A Standards Based Architecture

    NASA Astrophysics Data System (ADS)

    Simonis, Ingo

    2015-04-01

    A number of large-scale research projects are currently under way exploring the various components of citizen observatories, e.g. CITI-SENSE (http://www.citi-sense.eu), Citclops (http://citclops.eu), COBWEB (http://cobwebproject.eu), OMNISCIENTIS (http://www.omniscientis.eu), and WeSenseIt (http://www.wesenseit.eu). Common to all projects is the motivation to develop a platform enabling effective participation by citizens in environmental projects, while considering important aspects such as security, privacy, long-term storage and availability, accessibility of raw and processed data and its proper integration into catalogues and international exchange and collaboration systems such as GEOSS or INSPIRE. This paper describes the software architecture implemented for setting up crowdsourcing campaigns using standardized components, interfaces, security features, and distribution capabilities. It illustrates the Citizen Observatory Toolkit, a software suite that allows defining crowdsourcing campaigns, to invite registered and unregistered participants to participate in crowdsourcing campaigns, and to analyze, process, and visualize raw and quality enhanced crowd sourcing data and derived products. The Citizen Observatory Toolkit is not a single software product. Instead, it is a framework of components that are built using internationally adopted standards wherever possible (e.g. OGC standards from Sensor Web Enablement, GeoPackage, and Web Mapping and Processing Services, as well as security and metadata/cataloguing standards), defines profiles of those standards where necessary (e.g. SWE O&M profile, SensorML profile), and implements design decisions based on the motivation to maximize interoperability and reusability of all components. The toolkit contains tools to set up, manage and maintain crowdsourcing campaigns, allows building on-demand apps optimized for the specific sampling focus, supports offline and online sampling modes using modern cell phones with

  14. Implementation of medical monitor system based on networks

    NASA Astrophysics Data System (ADS)

    Yu, Hui; Cao, Yuzhen; Zhang, Lixin; Ding, Mingshi

    2006-11-01

    In this paper, the development trend of medical monitor system is analyzed and portable trend and network function become more and more popular among all kinds of medical monitor devices. The architecture of medical network monitor system solution is provided and design and implementation details of medical monitor terminal, monitor center software, distributed medical database and two kind of medical information terminal are especially discussed. Rabbit3000 system is used in medical monitor terminal to implement security administration of data transfer on network, human-machine interface, power management and DSP interface while DSP chip TMS5402 is used in signal analysis and data compression. Distributed medical database is designed for hospital center according to DICOM information model and HL7 standard. Pocket medical information terminal based on ARM9 embedded platform is also developed to interactive with center database on networks. Two kernels based on WINCE are customized and corresponding terminal software are developed for nurse's routine care and doctor's auxiliary diagnosis. Now invention patent of the monitor terminal is approved and manufacture and clinic test plans are scheduled. Applications for invention patent are also arranged for two medical information terminals.

  15. Application of the medical data warehousing architecture EPIDWARE to epidemiological follow-up: data extraction and transformation.

    PubMed

    Kerkri, E; Quantin, C; Yetongnon, K; Allaert, F A; Dusserre, L

    1999-01-01

    In this paper, we present an application of EPIDWARE, medical data warehousing architecture, to our epidemiological follow-up project. The aim of this project is to extract and regroup information from various information systems for epidemiological studies. We give a description of the requirements of the epidemiological follow-up project such as anonymity of medical data information and data file linkage procedure. We introduce the concept of Data Warehousing Architecture. The particularities of data extraction and transformation are presented and discussed.

  16. Model-Drive Architecture for Agent-Based Systems

    NASA Technical Reports Server (NTRS)

    Gradanin, Denis; Singh, H. Lally; Bohner, Shawn A.; Hinchey, Michael G.

    2004-01-01

    The Model Driven Architecture (MDA) approach uses a platform-independent model to define system functionality, or requirements, using some specification language. The requirements are then translated to a platform-specific model for implementation. An agent architecture based on the human cognitive model of planning, the Cognitive Agent Architecture (Cougaar) is selected for the implementation platform. The resulting Cougaar MDA prescribes certain kinds of models to be used, how those models may be prepared and the relationships of the different kinds of models. Using the existing Cougaar architecture, the level of application composition is elevated from individual components to domain level model specifications in order to generate software artifacts. The software artifacts generation is based on a metamodel. Each component maps to a UML structured component which is then converted into multiple artifacts: Cougaar/Java code, documentation, and test cases.

  17. Case-based medical informatics

    PubMed Central

    Pantazi, Stefan V; Arocha, José F; Moehr, Jochen R

    2004-01-01

    Background The "applied" nature distinguishes applied sciences from theoretical sciences. To emphasize this distinction, we begin with a general, meta-level overview of the scientific endeavor. We introduce the knowledge spectrum and four interconnected modalities of knowledge. In addition to the traditional differentiation between implicit and explicit knowledge we outline the concepts of general and individual knowledge. We connect general knowledge with the "frame problem," a fundamental issue of artificial intelligence, and individual knowledge with another important paradigm of artificial intelligence, case-based reasoning, a method of individual knowledge processing that aims at solving new problems based on the solutions to similar past problems. We outline the fundamental differences between Medical Informatics and theoretical sciences and propose that Medical Informatics research should advance individual knowledge processing (case-based reasoning) and that natural language processing research is an important step towards this goal that may have ethical implications for patient-centered health medicine. Discussion We focus on fundamental aspects of decision-making, which connect human expertise with individual knowledge processing. We continue with a knowledge spectrum perspective on biomedical knowledge and conclude that case-based reasoning is the paradigm that can advance towards personalized healthcare and that can enable the education of patients and providers. We center the discussion on formal methods of knowledge representation around the frame problem. We propose a context-dependent view on the notion of "meaning" and advocate the need for case-based reasoning research and natural language processing. In the context of memory based knowledge processing, pattern recognition, comparison and analogy-making, we conclude that while humans seem to naturally support the case-based reasoning paradigm (memory of past experiences of problem-solving and

  18. A unified architecture for biomedical search engines based on semantic web technologies.

    PubMed

    Jalali, Vahid; Matash Borujerdi, Mohammad Reza

    2011-04-01

    There is a huge growth in the volume of published biomedical research in recent years. Many medical search engines are designed and developed to address the over growing information needs of biomedical experts and curators. Significant progress has been made in utilizing the knowledge embedded in medical ontologies and controlled vocabularies to assist these engines. However, the lack of common architecture for utilized ontologies and overall retrieval process, hampers evaluating different search engines and interoperability between them under unified conditions. In this paper, a unified architecture for medical search engines is introduced. Proposed model contains standard schemas declared in semantic web languages for ontologies and documents used by search engines. Unified models for annotation and retrieval processes are other parts of introduced architecture. A sample search engine is also designed and implemented based on the proposed architecture in this paper. The search engine is evaluated using two test collections and results are reported in terms of precision vs. recall and mean average precision for different approaches used by this search engine.

  19. Model-based engineering for medical-device software.

    PubMed

    Ray, Arnab; Jetley, Raoul; Jones, Paul L; Zhang, Yi

    2010-01-01

    This paper demonstrates the benefits of adopting model-based design techniques for engineering medical device software. By using a patient-controlled analgesic (PCA) infusion pump as a candidate medical device, the authors show how using models to capture design information allows for i) fast and efficient construction of executable device prototypes ii) creation of a standard, reusable baseline software architecture for a particular device family, iii) formal verification of the design against safety requirements, and iv) creation of a safety framework that reduces verification costs for future versions of the device software. 1.

  20. Modeling the Europa Pathfinder avionics system with a model based avionics architecture tool

    NASA Technical Reports Server (NTRS)

    Chau, S.; Traylor, M.; Hall, R.; Whitfield, A.

    2002-01-01

    In order to shorten the avionics architecture development time, the Jet Propulsion Laboratory has developed a model-based architecture simultion tool called the Avionics System Architecture Tool (ASAT).

  1. Multi-provider architecture for cloud outsourcing of medical imaging repositories.

    PubMed

    Godinho, Tiago Marques; Bastião Silva, Luís A; Costa, Carlos; Oliveira, José Luís

    2014-01-01

    Over the last few years, the extended usage of medical imaging procedures has raised the medical community attention towards the optimization of their workflows. More recently, the federation of multiple institutions into a seamless distribution network has brought hope of increased quality healthcare services along with more efficient resource management. As a result, medical institutions are constantly looking for the best infrastructure to deploy their imaging archives. In this scenario, public cloud infrastructures arise as major candidates, as they offer elastic storage space, optimal data availability without great requirements of maintenance costs or IT personnel, in a pay-as-you-go model. However, standard methodologies still do not take full advantage of outsourced archives, namely because their integration with other in-house solutions is troublesome. This document proposes a multi-provider architecture for integration of outsourced archives with in-house PACS resources, taking advantage of foreign providers to store medical imaging studies, without disregarding security. It enables the retrieval of images from multiple archives simultaneously, improving performance, data availability and avoiding the vendor-locking problem. Moreover it enables load balancing and cache techniques.

  2. Systems modeling of space medical support architecture: topological mapping of high level characteristics and constraints.

    PubMed

    Musson, David M; Doyle, Thomas E; Saary, Joan

    2012-01-01

    The challenges associated with providing medical support to astronauts on long duration lunar or planetary missions are significant. Experience to date in space has included short duration missions to the lunar surface and both short and long duration stays on board spacecraft and space stations in low Earth orbit. Live actor, terrestrial analogue setting simulation provides a means of studying multiple aspects of the medical challenges of exploration class space missions, though few if any published models exist upon which to construct systems-simulation test beds. Current proposed and projected moon mission scenarios were analyzed from a systems perspective to construct such a model. A resulting topological mapping of high-level architecture for a reference lunar mission with presumed EVA excursion and international mission partners is presented. High-level descriptions of crew operational autonomy, medical support related to crew-member status, and communication characteristics within and between multiple teams are presented. It is hoped this modeling will help guide future efforts to simulate medical support operations for research purposes, such as in the use of live actor simulations in terrestrial analogue environments.

  3. Knowledge-based architecture for airborne mine and minefield detection

    NASA Astrophysics Data System (ADS)

    Agarwal, Sanjeev; Menon, Deepak; Swonger, C. W.

    2004-09-01

    One of the primary lessons learned from airborne mid-wave infrared (MWIR) based mine and minefield detection research and development over the last few years has been the fact that no single algorithm or static detection architecture is able to meet mine and minefield detection performance specifications. This is true not only because of the highly varied environmental and operational conditions under which an airborne sensor is expected to perform but also due to the highly data dependent nature of sensors and algorithms employed for detection. Attempts to make the algorithms themselves more robust to varying operating conditions have only been partially successful. In this paper, we present a knowledge-based architecture to tackle this challenging problem. The detailed algorithm architecture is discussed for such a mine/minefield detection system, with a description of each functional block and data interface. This dynamic and knowledge-driven architecture will provide more robust mine and minefield detection for a highly multi-modal operating environment. The acquisition of the knowledge for this system is predominantly data driven, incorporating not only the analysis of historical airborne mine and minefield imagery data collection, but also other "all source data" that may be available such as terrain information and time of day. This "all source data" is extremely important and embodies causal information that drives the detection performance. This information is not being used by current detection architectures. Data analysis for knowledge acquisition will facilitate better understanding of the factors that affect the detection performance and will provide insight into areas for improvement for both sensors and algorithms. Important aspects of this knowledge-based architecture, its motivations and the potential gains from its implementation are discussed, and some preliminary results are presented.

  4. Experimental APL system based on a multi-microprocessor architecture

    SciTech Connect

    Sakellardis, U.

    1983-01-01

    After an introduction dealing with the fundamental aspects and main extensions of APL, a programming language based on array operations, the author describes an experimental language, APL 90, which can take advantage of multi-microprocessor architecture to overcome many limitations of standard APL. 5 references.

  5. Efficient architecture for adaptive directional lifting-based wavelet transform

    NASA Astrophysics Data System (ADS)

    Yin, Zan; Zhang, Li; Shi, Guangming

    2010-07-01

    Adaptive direction lifting-based wavelet transform (ADL) has better performance than conventional lifting both in image compression and de-noising. However, no architecture has been proposed to hardware implement it because of its high computational complexity and huge internal memory requirements. In this paper, we propose a four-stage pipelined architecture for 2 Dimensional (2D) ADL with fast computation and high data throughput. The proposed architecture comprises column direction estimation, column lifting, row direction estimation and row lifting which are performed in parallel in a pipeline mode. Since the column processed data is transposed, the row processor can reuse the column processor which can decrease the design complexity. In the lifting step, predict and update are also performed in parallel. For an 8×8 image sub-block, the proposed architecture can finish the ADL forward transform within 78 clock cycles. The architecture is implemented on Xilinx Virtex5 device on which the frequency can achieve 367 MHz. The processed time is 212.5 ns, which can meet the request of real-time system.

  6. Neural network based architectures for aerospace applications

    NASA Technical Reports Server (NTRS)

    Ricart, Richard

    1987-01-01

    A brief history of the field of neural networks research is given and some simple concepts are described. In addition, some neural network based avionics research and development programs are reviewed. The need for the United States Air Force and NASA to assume a leadership role in supporting this technology is stressed.

  7. A web-services architecture designed for intermittent connectivity to support medical response to disasters.

    PubMed

    Brown, Steve; Griswold, William; Lenert, Leslie A

    2005-01-01

    To support mobile computing systems for first responders at mass casualty sites, as part of the WIISARD (Wireless Internet Information System for Medical Response in Disasters) project, we have developed a data architecture to gracefully handle an environment with frequent network failure and, multiple writers that also supports rapid dissemination of updates that could be critical to the safety of responders. This is accomplished by allowing for a subset of the overall information available in a disaster scene to be cached locally on a responder's device and locally modified with or without network access. When the network is available, the local subset of the model is automatically synchronized with a server that contains the full model, and conflicts are resolved. When changes from a device are committed, the changes are instantly sent to any connected devices where the local subset would be modified by the changes.

  8. Traffic and Driving Simulator Based on Architecture of Interactive Motion

    PubMed Central

    Paz, Alexander; Veeramisti, Naveen; Khaddar, Romesh; de la Fuente-Mella, Hanns; Modorcea, Luiza

    2015-01-01

    This study proposes an architecture for an interactive motion-based traffic simulation environment. In order to enhance modeling realism involving actual human beings, the proposed architecture integrates multiple types of simulation, including: (i) motion-based driving simulation, (ii) pedestrian simulation, (iii) motorcycling and bicycling simulation, and (iv) traffic flow simulation. The architecture has been designed to enable the simulation of the entire network; as a result, the actual driver, pedestrian, and bike rider can navigate anywhere in the system. In addition, the background traffic interacts with the actual human beings. This is accomplished by using a hybrid mesomicroscopic traffic flow simulation modeling approach. The mesoscopic traffic flow simulation model loads the results of a user equilibrium traffic assignment solution and propagates the corresponding traffic through the entire system. The microscopic traffic flow simulation model provides background traffic around the vicinities where actual human beings are navigating the system. The two traffic flow simulation models interact continuously to update system conditions based on the interactions between actual humans and the fully simulated entities. Implementation efforts are currently in progress and some preliminary tests of individual components have been conducted. The implementation of the proposed architecture faces significant challenges ranging from multiplatform and multilanguage integration to multievent communication and coordination. PMID:26491711

  9. Traffic and Driving Simulator Based on Architecture of Interactive Motion.

    PubMed

    Paz, Alexander; Veeramisti, Naveen; Khaddar, Romesh; de la Fuente-Mella, Hanns; Modorcea, Luiza

    2015-01-01

    This study proposes an architecture for an interactive motion-based traffic simulation environment. In order to enhance modeling realism involving actual human beings, the proposed architecture integrates multiple types of simulation, including: (i) motion-based driving simulation, (ii) pedestrian simulation, (iii) motorcycling and bicycling simulation, and (iv) traffic flow simulation. The architecture has been designed to enable the simulation of the entire network; as a result, the actual driver, pedestrian, and bike rider can navigate anywhere in the system. In addition, the background traffic interacts with the actual human beings. This is accomplished by using a hybrid mesomicroscopic traffic flow simulation modeling approach. The mesoscopic traffic flow simulation model loads the results of a user equilibrium traffic assignment solution and propagates the corresponding traffic through the entire system. The microscopic traffic flow simulation model provides background traffic around the vicinities where actual human beings are navigating the system. The two traffic flow simulation models interact continuously to update system conditions based on the interactions between actual humans and the fully simulated entities. Implementation efforts are currently in progress and some preliminary tests of individual components have been conducted. The implementation of the proposed architecture faces significant challenges ranging from multiplatform and multilanguage integration to multievent communication and coordination.

  10. Scalable, distributed data mining using an agent based architecture

    SciTech Connect

    Kargupta, H.; Hamzaoglu, I.; Stafford, B.

    1997-05-01

    Algorithm scalability and the distributed nature of both data and computation deserve serious attention in the context of data mining. This paper presents PADMA (PArallel Data Mining Agents), a parallel agent based system, that makes an effort to address these issues. PADMA contains modules for (1) parallel data accessing operations, (2) parallel hierarchical clustering, and (3) web-based data visualization. This paper describes the general architecture of PADMA and experimental results.

  11. Trust-based information system architecture for personal wellness.

    PubMed

    Ruotsalainen, Pekka; Nykänen, Pirkko; Seppälä, Antto; Blobel, Bernd

    2014-01-01

    Modern eHealth, ubiquitous health and personal wellness systems take place in an unsecure and ubiquitous information space where no predefined trust occurs. This paper presents novel information model and an architecture for trust based privacy management of personal health and wellness information in ubiquitous environment. The architecture enables a person to calculate a dynamic and context-aware trust value for each service provider, and using it to design personal privacy policies for trustworthy use of health and wellness services. For trust calculation a novel set of measurable context-aware and health information-sensitive attributes is developed. The architecture enables a person to manage his or her privacy in ubiquitous environment by formulating context-aware and service provider specific policies. Focus groups and information modelling was used for developing a wellness information model. System analysis method based on sequential steps that enable to combine results of analysis of privacy and trust concerns and the selection of trust and privacy services was used for development of the information system architecture. Its services (e.g. trust calculation, decision support, policy management and policy binding services) and developed attributes enable a person to define situation-aware policies that regulate the way his or her wellness and health information is processed.

  12. Data/knowledge Base Processing Using Optical Associative Architectures

    NASA Astrophysics Data System (ADS)

    Akyokus, Selim

    Optical storage, communication, and processing technologies will have a great impact on the future data/knowledge base processing systems. The use of optics in data/knowledge base processing requires new design methods, architectures, and algorithms to apply the optical technology successfully. In this dissertation, three optical associative architectures are proposed. The basic data element in the proposed systems is a 2-D data page. Pages of database relations are stored in a page-oriented optical mass memory, retrieved, and processed in parallel. The first architecture uses a 1-D optical content addressable memory (OCAM) as the main functional unit. A 1-D OCAM is basically an optical vector-matrix multiplier which works as a CAM due to the spatial coding used for bit matching and masking. A 1-D OCAM can compare a search argument with a data page in parallel. The second architecture uses a 2-D OCAM as a main functional unit. A 2-D OCAM is an optical matrix-matrix multiplier which enables the comparison of a page of search arguments with a data page in parallel and in a single step. This architecture allows the execution of multiple selection and join operations very fast. The third architecture uses an optical perfect shuffle network for data routing and a processing array for performing parallel logic operations. A processing array based on symbolic substitution logic is introduced, and the use of a smart SLM as processing array is discussed. The symbolic substitution rules and algorithms for the implementation of search and bitonic sort operations are given for the proposed system. The implementation of relational database operations: selection, projection, update, deletion, sorting, duplication removal, aggregation functions, join, and set operations are described for the proposed systems, timing equations are developed for each operation, and their performances are analyzed. The proposed architectures take advantage of one-to-one mapping among the physical

  13. Medical image denoising via optimal implementation of non-local means on hybrid parallel architecture.

    PubMed

    Nguyen, Tuan-Anh; Nakib, Amir; Nguyen, Huy-Nam

    2016-06-01

    The Non-local means denoising filter has been established as gold standard for image denoising problem in general and particularly in medical imaging due to its efficiency. However, its computation time limited its applications in real world application, especially in medical imaging. In this paper, a distributed version on parallel hybrid architecture is proposed to solve the computation time problem and a new method to compute the filters' coefficients is also proposed, where we focused on the implementation and the enhancement of filters' parameters via taking the neighborhood of the current voxel more accurately into account. In terms of implementation, our key contribution consists in reducing the number of shared memory accesses. The different tests of the proposed method were performed on the brain-web database for different levels of noise. Performances and the sensitivity were quantified in terms of speedup, peak signal to noise ratio, execution time, the number of floating point operations. The obtained results demonstrate the efficiency of the proposed method. Moreover, the implementation is compared to that of other techniques, recently published in the literature.

  14. Enabling protocol-based medical critiquing.

    PubMed

    Sips, Robert-Jan; Braun, Loes; Roos, Nico

    2006-01-01

    This paper investigates the combination of expert critiquing systems and formal medical protocols. Medical protocols might serve as a suitable basis for an expert critiquing system because of the ongoing acceptance of medical protocols and the rise of both evidence-based practice and evidence-based protocols. A prerequisite for a critiquing system based on medical protocols is the ability to match the actions a physician performs in practice to actions prescribed by a protocol. Previous research has shown that this is quite difficult, due to the fact that computerized systems are unable to handle deviations from a protocol, which are common in the medical domain. Our solution to this problem is based on extracting the intention underlying a physician's action and uses the intention as the basis for matching performed actions to prescribed actions. We propose an algorithm for the intention-based matching process and we evaluate the matching algorithm on 12 cases of hyperbilirubinemia in healthy term newborns.

  15. A Web-based architecture for the intelligent management of chronic patients.

    PubMed Central

    Riva, A.

    1996-01-01

    We describe a distributed architecture for medical informatics applications, based on the World-Wide Web (WWW) environment. After discussing previous experiences in the application of the WWW for medical purposes, we outline the features of a Common Lisp HTTP server designed to provide access to medical informatics applications using a standard Web browser. As an example of application, we describe a system for therapy planning and revision in the field of insulin-dependent diabetes. The system performs automatic data analysis and interpretation and provides advice on possible adjustments to the therapeutic protocol that the patients are following, taking advantage of the network and multimedia capabilities offered by the WWW for user interaction. PMID:8947652

  16. Innovative fiber-laser architecture-based compact wind lidar

    NASA Astrophysics Data System (ADS)

    Prasad, Narasimha S.; Tracy, Allen; Vetorino, Steve; Higgins, Richard; Sibell, Russ

    2016-03-01

    This paper describes an innovative, compact and eyesafe coherent lidar system developed for use in wind and wake vortex sensing applications. This advanced lidar system is field ruggedized with reduced size, weight, and power consumption (SWaP) configured based on an all-fiber and modular architecture. The all-fiber architecture is developed using a fiber seed laser that is coupled to uniquely configured fiber amplifier modules and associated photonic elements including an integrated 3D scanner. The scanner provides user programmable continuous 360 degree azimuth and 180 degree elevation scan angles. The system architecture eliminates free-space beam alignment issues and allows plug and play operation using graphical user interface software modules. Besides its all fiber architecture, the lidar system also provides pulsewidth agility to aid in improving range resolution. Operating at 1.54 microns and with a PRF of up to 20 KHz, the wind lidar is air cooled with overall dimensions of 30" x 46" x 60" and is designed as a Class 1 system. This lidar is capable of measuring wind velocities greater than 120 +/- 0.2 m/s over ranges greater than 10 km and with a range resolution of less than 15 m. This compact and modular system is anticipated to provide mobility, reliability, and ease of field deployment for wind and wake vortex measurements. The current lidar architecture is amenable for trace gas sensing and as such it is being evolved for airborne and space based platforms. In this paper, the key features of wind lidar instrumentation and its functionality are discussed followed by results of recent wind forecast measurements on a wind farm.

  17. A Hybrid Power Management (HPM) Based Vehicle Architecture

    NASA Technical Reports Server (NTRS)

    Eichenberg, Dennis J.

    2011-01-01

    Society desires vehicles with reduced fuel consumption and reduced emissions. This presents a challenge and an opportunity for industry and the government. The NASA John H. Glenn Research Center (GRC) has developed a Hybrid Power Management (HPM) based vehicle architecture for space and terrestrial vehicles. GRC's Electrical and Electromagnetics Branch of the Avionics and Electrical Systems Division initiated the HPM Program for the GRC Technology Transfer and Partnership Office. HPM is the innovative integration of diverse, state-of-the-art power devices in an optimal configuration for space and terrestrial applications. The appropriate application and control of the various power devices significantly improves overall system performance and efficiency. The basic vehicle architecture consists of a primary power source, and possibly other power sources, providing all power to a common energy storage system, which is used to power the drive motors and vehicle accessory systems, as well as provide power as an emergency power system. Each component is independent, permitting it to be optimized for its intended purpose. This flexible vehicle architecture can be applied to all vehicles to considerably improve system efficiency, reliability, safety, security, and performance. This unique vehicle architecture has the potential to alleviate global energy concerns, improve the environment, stimulate the economy, and enable new missions.

  18. Optimizing medical data quality based on multiagent web service framework.

    PubMed

    Wu, Ching-Seh; Khoury, Ibrahim; Shah, Hemant

    2012-07-01

    One of the most important issues in e-healthcare information systems is to optimize the medical data quality extracted from distributed and heterogeneous environments, which can extremely improve diagnostic and treatment decision making. This paper proposes a multiagent web service framework based on service-oriented architecture for the optimization of medical data quality in the e-healthcare information system. Based on the design of the multiagent web service framework, an evolutionary algorithm (EA) for the dynamic optimization of the medical data quality is proposed. The framework consists of two main components; first, an EA will be used to dynamically optimize the composition of medical processes into optimal task sequence according to specific quality attributes. Second, a multiagent framework will be proposed to discover, monitor, and report any inconstancy between the optimized task sequence and the actual medical records. To demonstrate the proposed framework, experimental results for a breast cancer case study are provided. Furthermore, to show the unique performance of our algorithm, a comparison with other works in the literature review will be presented.

  19. Autonomous, Decentralized Grid Architecture: Prosumer-Based Distributed Autonomous Cyber-Physical Architecture for Ultra-Reliable Green Electricity Networks

    SciTech Connect

    2012-01-11

    GENI Project: Georgia Tech is developing a decentralized, autonomous, internet-like control architecture and control software system for the electric power grid. Georgia Tech’s new architecture is based on the emerging concept of electricity prosumers—economically motivated actors that can produce, consume, or store electricity. Under Georgia Tech’s architecture, all of the actors in an energy system are empowered to offer associated energy services based on their capabilities. The actors achieve their sustainability, efficiency, reliability, and economic objectives, while contributing to system-wide reliability and efficiency goals. This is in marked contrast to the current one-way, centralized control paradigm.

  20. Cluster-based architecture for fault-tolerant quantum computation

    SciTech Connect

    Fujii, Keisuke; Yamamoto, Katsuji

    2010-04-15

    We present a detailed description of an architecture for fault-tolerant quantum computation, which is based on the cluster model of encoded qubits. In this cluster-based architecture, concatenated computation is implemented in a quite different way from the usual circuit-based architecture where physical gates are recursively replaced by logical gates with error-correction gadgets. Instead, some relevant cluster states, say fundamental clusters, are recursively constructed through verification and postselection in advance for the higher-level one-way computation, which namely provides error-precorrection of gate operations. A suitable code such as the Steane seven-qubit code is adopted for transversal operations. This concatenated construction of verified fundamental clusters has a simple transversal structure of logical errors, and achieves a high noise threshold {approx}3% for computation by using appropriate verification procedures. Since the postselection is localized within each fundamental cluster with the help of deterministic bare controlled-Z gates without verification, divergence of resources is restrained, which reconciles postselection with scalability.

  1. Cluster-based architecture for fault-tolerant quantum computation

    NASA Astrophysics Data System (ADS)

    Fujii, Keisuke; Yamamoto, Katsuji

    2010-04-01

    We present a detailed description of an architecture for fault-tolerant quantum computation, which is based on the cluster model of encoded qubits. In this cluster-based architecture, concatenated computation is implemented in a quite different way from the usual circuit-based architecture where physical gates are recursively replaced by logical gates with error-correction gadgets. Instead, some relevant cluster states, say fundamental clusters, are recursively constructed through verification and postselection in advance for the higher-level one-way computation, which namely provides error-precorrection of gate operations. A suitable code such as the Steane seven-qubit code is adopted for transversal operations. This concatenated construction of verified fundamental clusters has a simple transversal structure of logical errors, and achieves a high noise threshold ~3% for computation by using appropriate verification procedures. Since the postselection is localized within each fundamental cluster with the help of deterministic bare controlled-Z gates without verification, divergence of resources is restrained, which reconciles postselection with scalability.

  2. Packet Forwarding Scheme Based on Interworking Architecture for Future Internet

    NASA Astrophysics Data System (ADS)

    Kim, Seokhoon; Ryoo, Intae

    This paper introduces a packet forwarding scheme based on interworking architecture that can provide quite a good QoS by minimizing processing delay which is the major part of the timeliness factor in New Generation IP-based networks. Based on path and resource reservation mechanism, the POSIA makes routers on the packet forwarding path synchronize with each other and then forward packets. We have shown that the POSIA outperforms the existing packet forwarding schemes like IntServ, DiffServ and MPLS through computer simulations using OPNET.

  3. An Object-Based Architecture for Biomedical Expert Database Systems

    PubMed Central

    Barsalou, Thierry

    1988-01-01

    Objects play a major role in both database and artificial intelligence research. In this paper, we present a novel architecture for expert database systems that introduces an object-based interface between relational databases and expert systems. We exploit a semantic model of the database structure to map relations automatically into object templates, where each template can be a complex combination of join and projection operations. Moreover, we arrange the templates into object networks that represent different views of the same database. Separate processes instantiate those templates using data from the base relations, cache the resulting instances in main memory, navigate through a given network's objects, and update the database according to changes made at the object layer. In the context of an immunologic-research application, we demonstrate the capabilities of a prototype implementation of the architecture. The resulting model provides enhanced tools for database structuring and manipulation. In addition, this architecture supports efficient bidirectional communication between database and expert systems through the shared object layer.

  4. SIFT - A Component-Based Integration Architecture for Enterprise Analytics

    SciTech Connect

    Thurman, David A.; Almquist, Justin P.; Gorton, Ian; Wynne, Adam S.; Chatterton, Jack

    2007-02-01

    Architectures and technologies for enterprise application integration are relatively mature, resulting in a range of standards-based and proprietary middleware technologies. In the domain of complex analytical applications, integration architectures are not so well understood. Analytical applications such as those used in scientific discovery, emergency response, financial and intelligence analysis exert unique demands on their underlying architecture. These demands make existing integration middleware inappropriate for use in enterprise analytics environments. In this paper we describe SIFT (Scalable Information Fusion and Triage), a platform designed for integrating the various components that comprise enterprise analytics applications. SIFT exploits a common pattern for composing analytical components, and extends an existing messaging platform with dynamic configuration mechanisms and scaling capabilities. We demonstrate the use of SIFT to create a decision support platform for quality control based on large volumes of incoming delivery data. The strengths of the SIFT solution are discussed, and we conclude by describing where further work is required to create a complete solution applicable to a wide range of analytical application domains.

  5. Do Performance-Based Codes Support Universal Design in Architecture?

    PubMed

    Grangaard, Sidse; Frandsen, Anne Kathrine

    2016-01-01

    The research project 'An analysis of the accessibility requirements' studies how Danish architectural firms experience the accessibility requirements of the Danish Building Regulations and it examines their opinions on how future regulative models can support innovative and inclusive design - Universal Design (UD). The empirical material consists of input from six workshops to which all 700 Danish Architectural firms were invited, as well as eight group interviews. The analysis shows that the current prescriptive requirements are criticized for being too homogenous and possibilities for differentiation and zoning are required. Therefore, a majority of professionals are interested in a performance-based model because they think that such a model will support 'accessibility zoning', achieving flexibility because of different levels of accessibility in a building due to its performance. The common understanding of accessibility and UD is directly related to buildings like hospitals and care centers. When the objective is both innovative and inclusive architecture, the request of a performance-based model should be followed up by a knowledge enhancement effort in the building sector. Bloom's taxonomy of educational objectives is suggested as a tool for such a boost. The research project has been financed by the Danish Transport and Construction Agency.

  6. The AI Bus architecture for distributed knowledge-based systems

    NASA Technical Reports Server (NTRS)

    Schultz, Roger D.; Stobie, Iain

    1991-01-01

    The AI Bus architecture is layered, distributed object oriented framework developed to support the requirements of advanced technology programs for an order of magnitude improvement in software costs. The consequent need for highly autonomous computer systems, adaptable to new technology advances over a long lifespan, led to the design of an open architecture and toolbox for building large scale, robust, production quality systems. The AI Bus accommodates a mix of knowledge based and conventional components, running on heterogeneous, distributed real world and testbed environment. The concepts and design is described of the AI Bus architecture and its current implementation status as a Unix C++ library or reusable objects. Each high level semiautonomous agent process consists of a number of knowledge sources together with interagent communication mechanisms based on shared blackboards and message passing acquaintances. Standard interfaces and protocols are followed for combining and validating subsystems. Dynamic probes or demons provide an event driven means for providing active objects with shared access to resources, and each other, while not violating their security.

  7. Reconfigurable architecture for MIMO systems based on CORDIC operators

    NASA Astrophysics Data System (ADS)

    Wang, Hongzhi; Leray, Pierre; Palicot, Jacques

    2006-09-01

    The MIMO system is an attractive technology for wireless 3G/4G systems. In this article we propose the realization on FPGA of a MIMO 'V-BLAST Square Root' algorithm based on a variable number of CORDIC operators. The CORDIC operator is highly suitable for this implementation as it only relies on simple techniques of addition and vector offsets. This square root algorithm architecture is reconfigurable in order to adapt itself to different numbers of antennas and different data rates. The proposed architecture can achieve a data rate of 600 Mbit/s in a Virtex-II FPGA circuit from Xilinx for the MIMO system with QPSK modulation. To cite this article: H. Wang et al., C. R. Physique 7 (2006).

  8. A safety-based decision making architecture for autonomous systems

    NASA Technical Reports Server (NTRS)

    Musto, Joseph C.; Lauderbaugh, L. K.

    1991-01-01

    Engineering systems designed specifically for space applications often exhibit a high level of autonomy in the control and decision-making architecture. As the level of autonomy increases, more emphasis must be placed on assimilating the safety functions normally executed at the hardware level or by human supervisors into the control architecture of the system. The development of a decision-making structure which utilizes information on system safety is detailed. A quantitative measure of system safety, called the safety self-information, is defined. This measure is analogous to the reliability self-information defined by McInroy and Saridis, but includes weighting of task constraints to provide a measure of both reliability and cost. An example is presented in which the safety self-information is used as a decision criterion in a mobile robot controller. The safety self-information is shown to be consistent with the entropy-based Theory of Intelligent Machines defined by Saridis.

  9. GEARS: An Enterprise Architecture Based On Common Ground Services

    NASA Astrophysics Data System (ADS)

    Petersen, S.

    2014-12-01

    Earth observation satellites collect a broad variety of data used in applications that range from weather forecasting to climate monitoring. Within NOAA the National Environmental Satellite Data and Information Service (NESDIS) supports these applications by operating satellites in both geosynchronous and polar orbits. Traditionally NESDIS has acquired and operated its satellites as stand-alone systems with their own command and control, mission management, processing, and distribution systems. As the volume, velocity, veracity, and variety of sensor data and products produced by these systems continues to increase, NESDIS is migrating to a new concept of operation in which it will operate and sustain the ground infrastructure as an integrated Enterprise. Based on a series of common ground services, the Ground Enterprise Architecture System (GEARS) approach promises greater agility, flexibility, and efficiency at reduced cost. This talk describes the new architecture and associated development activities, and presents the results of initial efforts to improve product processing and distribution.

  10. Space-Based Information Infrastructure Architecture for Broadband Services

    NASA Technical Reports Server (NTRS)

    Price, Kent M.; Inukai, Tom; Razdan, Rajendev; Lazeav, Yvonne M.

    1996-01-01

    This study addressed four tasks: (1) identify satellite-addressable information infrastructure markets; (2) perform network analysis for space-based information infrastructure; (3) develop conceptual architectures; and (4) economic assessment of architectures. The report concludes that satellites will have a major role in the national and global information infrastructure, requiring seamless integration between terrestrial and satellite networks. The proposed LEO, MEO, and GEO satellite systems have satellite characteristics that vary widely. They include delay, delay variations, poorer link quality and beam/satellite handover. The barriers against seamless interoperability between satellite and terrestrial networks are discussed. These barriers are the lack of compatible parameters, standards and protocols, which are presently being evaluated and reduced.

  11. Content-Based Medical Image Retrieval

    NASA Astrophysics Data System (ADS)

    Müller, Henning; Deserno, Thomas M.

    This chapter details the necessity for alternative access concepts to the currently mainly text-based methods in medical information retrieval. This need is partly due to the large amount of visual data produced, the increasing variety of medical imaging data and changing user patterns. The stored visual data contain large amounts of unused information that, if well exploited, can help diagnosis, teaching and research. The chapter briefly reviews the history of image retrieval and its general methods before technologies that have been developed in the medical domain are focussed. We also discuss evaluation of medical content-based image retrieval (CBIR) systems and conclude with pointing out their strengths, gaps, and further developments. As examples, the MedGIFT project and the Image Retrieval in Medical Applications (IRMA) framework are presented.

  12. Practical Application of Model-based Programming and State-based Architecture to Space Missions

    NASA Technical Reports Server (NTRS)

    Horvath, Gregory; Ingham, Michel; Chung, Seung; Martin, Oliver; Williams, Brian

    2006-01-01

    A viewgraph presentation to develop models from systems engineers that accomplish mission objectives and manage the health of the system is shown. The topics include: 1) Overview; 2) Motivation; 3) Objective/Vision; 4) Approach; 5) Background: The Mission Data System; 6) Background: State-based Control Architecture System; 7) Background: State Analysis; 8) Overview of State Analysis; 9) Background: MDS Software Frameworks; 10) Background: Model-based Programming; 10) Background: Titan Model-based Executive; 11) Model-based Execution Architecture; 12) Compatibility Analysis of MDS and Titan Architectures; 13) Integrating Model-based Programming and Execution into the Architecture; 14) State Analysis and Modeling; 15) IMU Subsystem State Effects Diagram; 16) Titan Subsystem Model: IMU Health; 17) Integrating Model-based Programming and Execution into the Software IMU; 18) Testing Program; 19) Computationally Tractable State Estimation & Fault Diagnosis; 20) Diagnostic Algorithm Performance; 21) Integration and Test Issues; 22) Demonstrated Benefits; and 23) Next Steps

  13. Cavity-based architecture to preserve quantum coherence and entanglement.

    PubMed

    Man, Zhong-Xiao; Xia, Yun-Jie; Lo Franco, Rosario

    2015-09-09

    Quantum technology relies on the utilization of resources, like quantum coherence and entanglement, which allow quantum information and computation processing. This achievement is however jeopardized by the detrimental effects of the environment surrounding any quantum system, so that finding strategies to protect quantum resources is essential. Non-Markovian and structured environments are useful tools to this aim. Here we show how a simple environmental architecture made of two coupled lossy cavities enables a switch between Markovian and non-Markovian regimes for the dynamics of a qubit embedded in one of the cavity. Furthermore, qubit coherence can be indefinitely preserved if the cavity without qubit is perfect. We then focus on entanglement control of two independent qubits locally subject to such an engineered environment and discuss its feasibility in the framework of circuit quantum electrodynamics. With up-to-date experimental parameters, we show that our architecture allows entanglement lifetimes orders of magnitude longer than the spontaneous lifetime without local cavity couplings. This cavity-based architecture is straightforwardly extendable to many qubits for scalability.

  14. Cavity-based architecture to preserve quantum coherence and entanglement

    NASA Astrophysics Data System (ADS)

    Man, Zhong-Xiao; Xia, Yun-Jie; Lo Franco, Rosario

    2015-09-01

    Quantum technology relies on the utilization of resources, like quantum coherence and entanglement, which allow quantum information and computation processing. This achievement is however jeopardized by the detrimental effects of the environment surrounding any quantum system, so that finding strategies to protect quantum resources is essential. Non-Markovian and structured environments are useful tools to this aim. Here we show how a simple environmental architecture made of two coupled lossy cavities enables a switch between Markovian and non-Markovian regimes for the dynamics of a qubit embedded in one of the cavity. Furthermore, qubit coherence can be indefinitely preserved if the cavity without qubit is perfect. We then focus on entanglement control of two independent qubits locally subject to such an engineered environment and discuss its feasibility in the framework of circuit quantum electrodynamics. With up-to-date experimental parameters, we show that our architecture allows entanglement lifetimes orders of magnitude longer than the spontaneous lifetime without local cavity couplings. This cavity-based architecture is straightforwardly extendable to many qubits for scalability.

  15. Architectures for parallel DSP-based adaptive optics feedback control

    NASA Astrophysics Data System (ADS)

    McCarthy, Daniel F.

    1999-11-01

    We have developed a digital image processing system for real-time digital image processing feedback control of adaptive optics systems and simulation of optical image processing algorithms. The system uses multi-computer architecture to capture data from an imaging device such as a charge coupled device camera, process the image data, and control a spatial light-modulator, typically a liquid crystal modulator or a micro-electro mechanical system. The system is a Windows NT Pentium-based system combined with a commercial off-the-shelf peripheral component interconnect bus multi-processor system. The multi-processor is based on the Analog Devices super Harvard architecture computer (SHARC) processor, and field programmable gate arrays (FPGAs). The SHARCs provide a scalable reconfigurable C language-based digital signal processing (DSP) development environment. The FPGAs are typically used as reprogrammable interface controllers designed to integrate several off-the- shelf and custom imagers and light modulators into the system. The FPGAs can also be used in concert with the SHARCs for implementation of application-specific high-speed DSP algorithms.

  16. FPGA-based architecture for hyperspectral endmember extraction

    NASA Astrophysics Data System (ADS)

    Rosário, João.; Nascimento, José M. P.; Véstias, Mário

    2014-10-01

    Hyperspectral instruments have been incorporated in satellite missions, providing data of high spectral resolution of the Earth. This data can be used in remote sensing applications, such as, target detection, hazard prevention, and monitoring oil spills, among others. In most of these applications, one of the requirements of paramount importance is the ability to give real-time or near real-time response. Recently, onboard processing systems have emerged, in order to overcome the huge amount of data to transfer from the satellite to the ground station, and thus, avoiding delays between hyperspectral image acquisition and its interpretation. For this purpose, compact reconfigurable hardware modules, such as field programmable gate arrays (FPGAs) are widely used. This paper proposes a parallel FPGA-based architecture for endmember's signature extraction. This method based on the Vertex Component Analysis (VCA) has several advantages, namely it is unsupervised, fully automatic, and it works without dimensionality reduction (DR) pre-processing step. The architecture has been designed for a low cost Xilinx Zynq board with a Zynq-7020 SoC FPGA based on the Artix-7 FPGA programmable logic and tested using real hyperspectral data sets collected by the NASA's Airborne Visible Infra-Red Imaging Spectrometer (AVIRIS) over the Cuprite mining district in Nevada. Experimental results indicate that the proposed implementation can achieve real-time processing, while maintaining the methods accuracy, which indicate the potential of the proposed platform to implement high-performance, low cost embedded systems, opening new perspectives for onboard hyperspectral image processing.

  17. Simulation-based medical teaching and learning.

    PubMed

    Al-Elq, Abdulmohsen H

    2010-01-01

    One of the most important steps in curriculum development is the introduction of simulation- based medical teaching and learning. Simulation is a generic term that refers to an artificial representation of a real world process to achieve educational goals through experiential learning. Simulation based medical education is defined as any educational activity that utilizes simulation aides to replicate clinical scenarios. Although medical simulation is relatively new, simulation has been used for a long time in other high risk professions such as aviation. Medical simulation allows the acquisition of clinical skills through deliberate practice rather than an apprentice style of learning. Simulation tools serve as an alternative to real patients. A trainee can make mistakes and learn from them without the fear of harming the patient. There are different types and classification of simulators and their cost vary according to the degree of their resemblance to the reality, or 'fidelity'. Simulation- based learning is expensive. However, it is cost-effective if utilized properly. Medical simulation has been found to enhance clinical competence at the undergraduate and postgraduate levels. It has also been found to have many advantages that can improve patient safety and reduce health care costs through the improvement of the medical provider's competencies. The objective of this narrative review article is to highlight the importance of simulation as a new teaching method in undergraduate and postgraduate education.

  18. A reinforcement learning-based architecture for fuzzy logic control

    NASA Technical Reports Server (NTRS)

    Berenji, Hamid R.

    1992-01-01

    This paper introduces a new method for learning to refine a rule-based fuzzy logic controller. A reinforcement learning technique is used in conjunction with a multilayer neural network model of a fuzzy controller. The approximate reasoning based intelligent control (ARIC) architecture proposed here learns by updating its prediction of the physical system's behavior and fine tunes a control knowledge base. Its theory is related to Sutton's temporal difference (TD) method. Because ARIC has the advantage of using the control knowledge of an experienced operator and fine tuning it through the process of learning, it learns faster than systems that train networks from scratch. The approach is applied to a cart-pole balancing system.

  19. Human friendly architectural design for a small Martian base

    NASA Astrophysics Data System (ADS)

    Kozicki, J.; Kozicka, J.

    2011-12-01

    The manned mission to Mars is expected to last almost three years. A human factor must be taken seriously into account in such a long-term mission. A big comfortable habitat can help to overcome sociopsychological problems, that occur in ICEs (Isolated and Confined Environments). Authors have come forward to this issue and have developed a Martian base design as a human friendly habitat. The project is based on researches of extreme conditions on Mars, architecture in ICEs and contemporary building technologies. The base consists of five modules: a Central Module (CM), an Agriculture Dome (AD), a Residential Dome (RD), a Laboratory Dome (LD) and a Garage (G). Each element has its own functional purpose. The CM is a metal capsule similar to the Reference Mission module (RM, NASA, 1997). Domes are inflatable multilayer structures, which interiors are "open planned". Interiors can be arranged and divided into rooms by using modular partition walls designed by authors.

  20. A knowledge base architecture for distributed knowledge agents

    NASA Technical Reports Server (NTRS)

    Riedesel, Joel; Walls, Bryan

    1990-01-01

    A tuple space based object oriented model for knowledge base representation and interpretation is presented. An architecture for managing distributed knowledge agents is then implemented within the model. The general model is based upon a database implementation of a tuple space. Objects are then defined as an additional layer upon the database. The tuple space may or may not be distributed depending upon the database implementation. A language for representing knowledge and inference strategy is defined whose implementation takes advantage of the tuple space. The general model may then be instantiated in many different forms, each of which may be a distinct knowledge agent. Knowledge agents may communicate using tuple space mechanisms as in the LINDA model as well as using more well known message passing mechanisms. An implementation of the model is presented describing strategies used to keep inference tractable without giving up expressivity. An example applied to a power management and distribution network for Space Station Freedom is given.

  1. Transputer-based architecture for ATM LAN protocol testing

    NASA Astrophysics Data System (ADS)

    Di Concetto, M.; Crocetti, P.; Marino, G.; Merli, E.; Pavesi, M.; Zizza, F.

    1993-10-01

    Local Area Networks (LANs) have completed two generations of development (Ethernet and Token Ring the first, and FDDI and DQDB the second); the large volumes of traffic involved in the emerging multimedia applications, however, lead towards a third generation of LANs. This generation must provide real-time capabilities needed by new services and solve the problems of interworking with ATM-based B-ISDN. Moreover the possibility to vary the subscribed bandwidth with the B-ISDN will be given to the LAN interfaces. This paper focuses on an architecture for protocol testing of a Dynamic Bandwidth Allocation Protocol inserted in a LAN environment based on ATM technology. In fact, the technology of the third LAN generation will be the Asynchronous Transfer Mode solving every interface problem with the public B-ISDN. A testing and debugging environment which checks the implementation of the Dynamic Bandwidth Allocation Protocol at the interface host/LAN- ATM is discussed. The main concepts of the overall system architecture are analyzed, evidencing both software and hardware issues.

  2. Applying XDS for sharing CDA-based medical records

    NASA Astrophysics Data System (ADS)

    Kim, Joong Il; Jang, Bong Mun; Han, Dong Hoon; Yang, Keon Ho; Kang, Won-Suk; Jung, Haijo; Kim, Hee-Joung

    2006-03-01

    Many countries have set long-term objectives for establishing an Electronic Healthcare Records system(EHRs). Various IT Strategies note that integration of EHR systems has a high priority. Because the EHR systems are based on different information models and different technology platforms, one of the key integration problems in the realization of the EHRs for the continuity of patient care, is the inability to share patient records between various institutions. Integrating the Healthcare Enterprise (IHE) committee has defined the detailed implementations of existing standards such as DICOM, HL7, in a publicly available document called the IHE technical framework (IHE-TF). Cross-enterprise document sharing (XDS), one of IHE technical frameworks, is describing how to apply the standards into the information systems for the sharing of medical documents among hospitals. This study aims to design Clinical Document Architecture (CDA) schema based on HL7, and to apply implementation strategies of XDS using this CDA schema.

  3. [WEB-based medical data mining integration].

    PubMed

    Yao, Gang; Zhang, Xiaoxiang; Wang, Huoming

    2014-06-01

    An integration of medical data management system based on WEB and data mining tool is reportedly in this paper. In the application process of this system, web-based medical data mining user sends requests to the server by using client browser with http protocol, the commands are then received by the server and the server calls the data mining tools remote object for data processing, and the results are sent back to the customer browser through the http protocol and presented to the user. In order to prove the feasibility of the proposed solution, the test is done under the NET platform by using SAS and SPSS, and the detail steps are given. By the practical test, it was proved that the web-based data mining tool integration solutions proposed in this paper would have its broad prospects for development, which would open up a new route to the development of medical data mining.

  4. SoC-based architecture for biomedical signal processing.

    PubMed

    Gutiérrez-Rivas, R; Hernández, A; García, J J; Marnane, W

    2015-01-01

    Over the last decades, many algorithms have been proposed for processing biomedical signals. Most of these algorithms have been focused on the elimination of noise and artifacts existing in these signals, so they can be used for automatic monitoring and/or diagnosis applications. With regard to remote monitoring, the use of portable devices often requires a reduced number of resources and power consumption, being necessary to reach a trade-off between the accuracy of algorithms and their computational complexity. This paper presents a SoC (System-on-Chip) architecture, based on a FPGA (Field-Programmable Gate Array) device, suitable for the implementation of biomedical signal processing. The proposal has been successfully validated by implementing an efficient QRS complex detector. The results show that, using a reduced amount of resources, values of sensitivity and positive predictive value above 99.49% are achieved, which make the proposed approach suitable for telemedicine applications.

  5. Services oriented architecture (SOA)-based persistent ISR simulation system

    NASA Astrophysics Data System (ADS)

    Chen, Genshe; Blasch, Erik; Shen, Dan; Chen, Huimin; Pham, Khanh

    2010-04-01

    In the modern networked battlefield, network centric warfare (NCW) scenarios need to interoperate between shared resources and data assets such as sensors, UAVs, satellites, ground vehicles, and command and control (C2/C4I) systems. By linking and fusing platform routing information, sensor exploitation results, and databases (e.g. Geospatial Information Systems [GIS]), the shared situation awareness and mission effectiveness will be improved. Within the information fusion community, various research efforts are looking at open standard approaches to composing the heterogeneous network components under one framework for future modeling and simulation applications. By utilizing the open source services oriented architecture (SOA) based sensor web services, and GIS visualization services, we propose a framework that ensures the fast prototyping of intelligence, surveillance, and reconnaissance (ISR) system simulations to determine an asset mix for a desired mission effectiveness, performance modeling for sensor management and prediction, and user testing of various scenarios.

  6. Branched Macromolecular Architectures for Degradable, Multifunctional Phosphorus-Based Polymers.

    PubMed

    Henke, Helena; Brüggemann, Oliver; Teasdale, Ian

    2017-02-01

    This feature article briefly highlights some of the recent advances in polymers in which phosphorus is an integral part of the backbone, with a focus on the preparation of functional, highly branched, soluble polymers. A comparison is made between the related families of materials polyphosphazenes, phosphazene/phosphorus-based dendrimers and polyphosphoesters. The work described herein shows this to be a rich and burgeoning field, rapidly catching up with organic chemistry in terms of the macromolecular synthetic control and variety of available macromolecular architectures, whilst offering unique property combinations not available with carbon backbones, such as tunable degradation rates, high multi-valency and facile post-polymerization functionalization. As an example of their use in advanced applications, we highlight some investigations into their use as water-soluble drug carriers, whereby in particular the degradability in combination with multivalent nature has made them useful materials, as underlined by some of the recent studies in this area.

  7. Different micromanipulation applications based on common modular control architecture

    NASA Astrophysics Data System (ADS)

    Sipola, Risto; Vallius, Tero; Pudas, Marko; Röning, Juha

    2010-01-01

    This paper validates a previously introduced scalable modular control architecture and shows how it can be used to implement research equipment. The validation is conducted by presenting different kinds of micromanipulation applications that use the architecture. Conditions of the micro-world are very different from those of the macro-world. Adhesive forces are significant compared to gravitational forces when micro-scale objects are manipulated. Manipulation is mainly conducted by automatic control relying on haptic feedback provided by force sensors. The validated architecture is a hierarchical layered hybrid architecture, including a reactive layer and a planner layer. The implementation of the architecture is modular, and the architecture has a lot in common with open architectures. Further, the architecture is extensible, scalable, portable and it enables reuse of modules. These are the qualities that we validate in this paper. To demonstrate the claimed features, we present different applications that require special control in micrometer, millimeter and centimeter scales. These applications include a device that measures cell adhesion, a device that examines properties of thin films, a device that measures adhesion of micro fibers and a device that examines properties of submerged gel produced by bacteria. Finally, we analyze how the architecture is used in these applications.

  8. Extensible knowledge-based architecture for segmenting CT data

    NASA Astrophysics Data System (ADS)

    Brown, Matthew S.; McNitt-Gray, Michael F.; Goldin, Jonathan G.; Aberle, Denise R.

    1998-06-01

    A knowledge-based system has been developed for segmenting computed tomography (CT) images. Its modular architecture includes an anatomical model, image processing engine, inference engine and blackboard. The model contains a priori knowledge of size, shape, X-ray attenuation and relative position of anatomical structures. This knowledge is used to constrain low-level segmentation routines. Model-derived constraints and segmented image objects are both transformed into a common feature space and posted on the blackboard. The inference engine then matches image to model objects, based on the constraints. The transformation to feature space allows the knowledge and image data representations to be independent. Thus a high-level model can be used, with data being stored in a frame-based semantic network. This modularity and explicit representation of knowledge allows for straightforward system extension. We initially demonstrate an application to lung segmentation in thoracic CT, with subsequent extension of the knowledge-base to include tumors within the lung fields. The anatomical model was later augmented to include basic brain anatomy including the skull and blood vessels, to allow automatic segmentation of vascular structures in CT angiograms for 3D rendering and visualization.

  9. Smart sensor-based geospatial architecture for dike monitoring

    NASA Astrophysics Data System (ADS)

    Herle, S.; Becker, R.; Blankenbach, J.

    2016-04-01

    Artificial hydraulic structures like dams or dikes used for water level regulations or flood prevention are continuously under the influence of the weather and variable river regimes. Thus, ongoing monitoring and simulation is crucial in order to determine the inner condition. Potentially life-threatening situations, in extreme case a failure, must be counteracted by all available means. Nowadays flood warning systems rely exclusively on water level forecast without considering the state of the structure itself. Area-covering continuous knowledge of the inner state including time dependent changes increases the capability of recognizing and locating vulnerable spots for early treatment. In case of a predicted breach, advance warning time for alerting affected citizens can be extended. Our approach is composed of smart sensors integrated in a service-oriented geospatial architecture to monitor and simulate artificial hydraulic structures continuously. The sensors observe the inner state of the construction like the soil moisture or the stress and deformation over time but also various external influences like water levels or wind speed. They are interconnected in distributed network architecture by a so-called sensor bus system based on lightweight protocols like Message Queue Telemetry Transport for Sensor Networks (MQTT-SN). These sensor data streams are transferred into an OGC Sensor Web Enablement (SWE) data structure providing high-level geo web services to end users. Bundled with 3rd party geo web services (WMS etc.) powerful processing and simulation tools can be invoked using the Web Processing Service (WPS) standard. Results will be visualized in a geoportal allowing user access to all information.

  10. Architecture-Based Refinements for Secure Computer Systems Design

    DTIC Science & Technology

    2006-01-01

    Government. REFERENCES [1] N. S. Rosa, G. R. R. Justo , and P. R. F. Cunha, “A framework for building non-functional software architectures,” in Proc. 2001 ACM...IWSSD’98), 1998, p. 60. [7] N. S. Rosa, G. R. R. Justo , and P. R. F. Cunha, “Incorporating non- functional requirements into software architectures,” in

  11. Water System Architectures for Moon and Mars Bases

    NASA Technical Reports Server (NTRS)

    Jones, Harry W.; Hodgson, Edward W.; Kliss, Mark H.

    2015-01-01

    Water systems for human bases on the moon and Mars will recycle multiple sources of wastewater. Systems for both the moon and Mars will also store water to support and backup the recycling system. Most water system requirements, such as number of crew, quantity and quality of water supply, presence of gravity, and surface mission duration of 6 or 18 months, will be similar for the moon and Mars. If the water system fails, a crew on the moon can quickly receive spare parts and supplies or return to Earth, but a crew on Mars cannot. A recycling system on the moon can have a reasonable reliability goal, such as only one unrecoverable failure every five years, if there is enough stored water to allow time for attempted repairs and for the crew to return if repair fails. The water system that has been developed and successfully operated on the International Space Station (ISS) could be used on a moon base. To achieve the same high level of crew safety on Mars without an escape option, either the recycling system must have much higher reliability or enough water must be stored to allow the crew to survive the full duration of the Mars surface mission. A three loop water system architecture that separately recycles condensate, wash water, and urine and flush can improve reliability and reduce cost for a Mars base.

  12. The simcyp population based simulator: architecture, implementation, and quality assurance.

    PubMed

    Jamei, Masoud; Marciniak, Steve; Edwards, Duncan; Wragg, Kris; Feng, Kairui; Barnett, Adrian; Rostami-Hodjegan, Amin

    2013-01-01

    Developing a user-friendly platform that can handle a vast number of complex physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) models both for conventional small molecules and larger biologic drugs is a substantial challenge. Over the last decade the Simcyp Population Based Simulator has gained popularity in major pharmaceutical companies (70% of top 40 - in term of R&D spending). Under the Simcyp Consortium guidance, it has evolved from a simple drug-drug interaction tool to a sophisticated and comprehensive Model Based Drug Development (MBDD) platform that covers a broad range of applications spanning from early drug discovery to late drug development. This article provides an update on the latest architectural and implementation developments within the Simulator. Interconnection between peripheral modules, the dynamic model building process and compound and population data handling are all described. The Simcyp Data Management (SDM) system, which contains the system and drug databases, can help with implementing quality standards by seamless integration and tracking of any changes. This also helps with internal approval procedures, validation and auto-testing of the new implemented models and algorithms, an area of high interest to regulatory bodies.

  13. Soft-core processor study for node-based architectures.

    SciTech Connect

    Van Houten, Jonathan Roger; Jarosz, Jason P.; Welch, Benjamin James; Gallegos, Daniel E.; Learn, Mark Walter

    2008-09-01

    Node-based architecture (NBA) designs for future satellite projects hold the promise of decreasing system development time and costs, size, weight, and power and positioning the laboratory to address other emerging mission opportunities quickly. Reconfigurable Field Programmable Gate Array (FPGA) based modules will comprise the core of several of the NBA nodes. Microprocessing capabilities will be necessary with varying degrees of mission-specific performance requirements on these nodes. To enable the flexibility of these reconfigurable nodes, it is advantageous to incorporate the microprocessor into the FPGA itself, either as a hardcore processor built into the FPGA or as a soft-core processor built out of FPGA elements. This document describes the evaluation of three reconfigurable FPGA based processors for use in future NBA systems--two soft cores (MicroBlaze and non-fault-tolerant LEON) and one hard core (PowerPC 405). Two standard performance benchmark applications were developed for each processor. The first, Dhrystone, is a fixed-point operation metric. The second, Whetstone, is a floating-point operation metric. Several trials were run at varying code locations, loop counts, processor speeds, and cache configurations. FPGA resource utilization was recorded for each configuration. Cache configurations impacted the results greatly; for optimal processor efficiency it is necessary to enable caches on the processors. Processor caches carry a penalty; cache error mitigation is necessary when operating in a radiation environment.

  14. [Network-based continuing medical education].

    PubMed

    Romanov, Kalle

    2011-01-01

    Network-based training can provide continuing medical education with methods, whose implementation by means of traditional training is difficult or practically impossible. By virtue of its chronological and geographical flexibility, educational application of the network may provide extra advantage for the trainee and the trainer. Implementation of network-based training is, however, demanding and laborious both technically and pedagogically, whereby organizations should strive for collaboration in organizing the training. In addition, the status of network-based continuing education in relation to the physician's working time should be clearly defined.

  15. Moon-Based Advanced Reusable Transportation Architecture: The MARTA Project

    NASA Astrophysics Data System (ADS)

    Alexander, R.; Bechtel, R.; Chen, T.; Cormier, T.; Kalaver, S.; Kirtas, M.; Lewe, J.-H.; Marcus, L.; Marshall, D.; Medlin, M.; McIntire, J.; Nelson, D.; Remolina, D.; Scott, A.; Weglian, J.; Olds, J.

    2000-01-01

    The Moon-based Advanced Reusable Transportation Architecture (MARTA) Project conducted an in-depth investigation of possible Low Earth Orbit (LEO) to lunar surface transportation systems capable of sending both astronauts and large masses of cargo to the Moon and back. This investigation was conducted from the perspective of a private company operating the transportation system for a profit. The goal of this company was to provide an Internal Rate of Return (IRR) of 25% to its shareholders. The technical aspect of the study began with a wide open design space that included nuclear rockets and tether systems as possible propulsion systems. Based on technical, political, and business considerations, the architecture was quickly narrowed down to a traditional chemical rocket using liquid oxygen and liquid hydrogen. However, three additional technologies were identified for further investigation: aerobraking, in-situ resource utilization (ISRU), and a mass driver on the lunar surface. These three technologies were identified because they reduce the mass of propellant used. Operational costs are the largest expense with propellant cost the largest contributor. ISRU, the production of materials using resources on the Moon, was considered because an Earth to Orbit (ETO) launch cost of 1600 per kilogram made taking propellant from the Earth's surface an expensive proposition. The use of an aerobrake to circularize the orbit of a vehicle coming from the Moon towards Earth eliminated 3, 100 meters per second of velocity change (Delta V), eliminating almost 30% of the 11,200 m/s required for one complete round trip. The use of a mass driver on the lunar surface, in conjunction with an ISRU production facility, would reduce the amount of propellant required by eliminating using propellant to take additional propellant from the lunar surface to Low Lunar Orbit (LLO). However, developing and operating such a system required further study to identify if it was cost effective. The

  16. A generalized locomotion CPG architecture based on oscillatory building blocks.

    PubMed

    Yang, Zhijun; França, Felipe M G

    2003-07-01

    Neural oscillation is one of the most extensively investigated topics of artificial neural networks. Scientific approaches to the functionalities of both natural and artificial intelligences are strongly related to mechanisms underlying oscillatory activities. This paper concerns itself with the assumption of the existence of central pattern generators (CPGs), which are the plausible neural architectures with oscillatory capabilities, and presents a discrete and generalized approach to the functionality of locomotor CPGs of legged animals. Based on scheduling by multiple edge reversal (SMER), a primitive and deterministic distributed algorithm, it is shown how oscillatory building block (OBB) modules can be created and, hence, how OBB-based networks can be formulated as asymmetric Hopfield-like neural networks for the generation of complex coordinated rhythmic patterns observed among pairs of biological motor neurons working during different gait patterns. It is also shown that the resulting Hopfield-like network possesses the property of reproducing the whole spectrum of different gaits intrinsic to the target locomotor CPGs. Although the new approach is not restricted to the understanding of the neurolocomotor system of any particular animal, hexapodal and quadrupedal gait patterns are chosen as illustrations given the wide interest expressed by the ongoing research in the area.

  17. The Pocket Medical Record—Do We Need a Centralized Medical Data Base?

    PubMed Central

    Ash, S. R.; Mertz, S. L.; Robinson, F. C.; Ulrich, D. K.

    1982-01-01

    As an alternative to a centralized, digital medical data base, a physically separate, microprocessor-generated, portable medical record has been developed. The medical information of this data base is processed and emphasized by physicians or nurses during their direct entry with the CNS* program. Implementation of the CNS program in several medical institutions has shown that the portable medical data base is “useful in transfer of medical information between such institutions, and the data base is adaptable to a variety of practice settings.

  18. Actuation mechanisms of carbon nanotube-based architectures

    NASA Astrophysics Data System (ADS)

    Geier, Sebastian; Mahrholz, Thorsten; Wierach, Peter; Sinapius, Michael

    2016-04-01

    State of the art smart materials such as piezo ceramics or electroactive polymers cannot feature both, mechanical stiffness and high active strain. Moreover, properties like low density, high mechanical stiffness and high strain at the same time driven by low energy play an increasingly important role for their future application. Carbon nanotubes (CNT), show this behavior. Their active behavior was observed 1999 the first time using paper-like mats made of CNT. Therefore the CNT-papers are electrical charged within an electrolyte thus forming a double- layer. The measured deflection of CNT material is based on the interaction between the charged high surface area formed by carbon nanotubes and ions provided by the electrolyte. Although CNT-papers have been extensively analyzed as well at the macro-scale as nano-scale there is still no generally accepted theory for the actuation mechanism. This paper focuses on investigations of the actuation mechanisms of CNT-papers in comparison to vertically aligned CNT-arrays. One reason of divergent results found in literature might be attributed to different types of CNT samples. While CNT-papers represent architectures of short CNTs which need to bridge each other to form the dimensions of the sample, the continuous CNTs of the array feature a length of almost 3 mm, along which the experiments are carried out. Both sample types are tested within an actuated tensile test set-up under different conditions. While the CNT-papers are tested in water-based electrolytes with comparably small redox-windows the hydrophobic CNT-arrays are tested in ionic liquids with comparatively larger redox-ranges. Furthermore an in-situ micro tensile test within an SEM is carried out to prove the optimized orientation of the MWCNTs as result of external load. It was found that the performance of CNT-papers strongly depends on the test conditions. However, the CNT-arrays are almost unaffected by the conditions showing active response at negative

  19. An event-based architecture for solving constraint satisfaction problems

    PubMed Central

    Mostafa, Hesham; Müller, Lorenz K.; Indiveri, Giacomo

    2015-01-01

    Constraint satisfaction problems are ubiquitous in many domains. They are typically solved using conventional digital computing architectures that do not reflect the distributed nature of many of these problems, and are thus ill-suited for solving them. Here we present a parallel analogue/digital hardware architecture specifically designed to solve such problems. We cast constraint satisfaction problems as networks of stereotyped nodes that communicate using digital pulses, or events. Each node contains an oscillator implemented using analogue circuits. The non-repeating phase relations among the oscillators drive the exploration of the solution space. We show that this hardware architecture can yield state-of-the-art performance on random SAT problems under reasonable assumptions on the implementation. We present measurements from a prototype electronic chip to demonstrate that a physical implementation of the proposed architecture is robust to practical non-idealities and to validate the theory proposed. PMID:26642827

  20. RAINBOW: Architecture-Based Adaptation of Complex Systems

    DTIC Science & Technology

    2005-04-01

    architectural level. The second problem is to translate architectural repairs into actual system changes. To do this we write a simple table-driven...bandwidth, regardless of the adaptation. Similarly, it is possible to use general probe technology to ameliorate the task of writing probes for particular...it is possible to use existing technologies like ProbeMeister [21] to generate the actual probes, without writing any additional code. 2.3

  1. An architecture for distributed video applications based on declarative networking

    NASA Astrophysics Data System (ADS)

    Wang, Xiping; Gonzales, Cesar; Lobo, Jorge; Calo, Seraphin; Verma, Dinesh

    2012-06-01

    Video surveillance applications are examples of complex distributed coalition tasks. Real-time capture and analysis of image sensor data is one of the most important tasks in a number of military critical decision making scenarios. In complex battlefield situations, there is a need to coordinate the operation of distributed image sensors and the analysis of their data as transmitted over a heterogeneous wireless network where bandwidth, power, and computational capabilities are constrained. There is also a need to automate decision making based on the results of the analysis of video data. Declarative Networking is a promising technology for controlling complex video surveillance applications in this sort of environment. This paper presents a flexible and extensible architecture for deploying distributed video surveillance applications using the declarative networking paradigm, which allows us to dynamically connect and manage distributed image sensors and deploy various modules for the analysis of video data to satisfy a variety of video surveillance requirements. With declarative computing, it becomes possible for us not only to express the program control structure in a declarative fashion, but also to simplify the management of distributed video surveillance applications.

  2. a New Architecture for Intelligent Systems with Logic Based Languages

    NASA Astrophysics Data System (ADS)

    Saini, K. K.; Saini, Sanju

    2008-10-01

    People communicate with each other in sentences that incorporate two kinds of information: propositions about some subject, and metalevel speech acts that specify how the propositional information is used—as an assertion, a command, a question, or a promise. By means of speech acts, a group of people who have different areas of expertise can cooperate and dynamically reconfigure their social interactions to perform tasks and solve problems that would be difficult or impossible for any single individual. This paper proposes a framework for intelligent systems that consist of a variety of specialized components together with logic-based languages that can express propositions and speech acts about those propositions. The result is a system with a dynamically changing architecture that can be reconfigured in various ways: by a human knowledge engineer who specifies a script of speech acts that determine how the components interact; by a planning component that generates the speech acts to redirect the other components; or by a committee of components, which might include human assistants, whose speech acts serve to redirect one another. The components communicate by sending messages to a Linda-like blackboard, in which components accept messages that are either directed to them or that they consider themselves competent to handle.

  3. Design and implementation of web-based mobile electronic medication administration record.

    PubMed

    Hsieh, Sung-Huai; Hou, I-Ching; Cheng, Po-Hsun; Tan, Ching-Ting; Shen, Po-Chao; Hsu, Kai-Ping; Hsieh, Sheau-Ling; Lai, Feipei

    2010-10-01

    Patients' safety is the most essential, critical issue, however, errors can hardly prevent, especially for human faults. In order to reduce the errors caused by human, we construct Electronic Health Records (EHR) in the Health Information System (HIS) to facilitate patients' safety and to improve the quality of medical care. During the medical care processing, all the tasks are based upon physicians' orders. In National Taiwan University Hospital (NTUH), the Electronic Health Record committee proposed a standard of order flows. There are objectives of the standard: first, to enhance medical procedures and enforce hospital policies; secondly, to improve the quality of medical care; third, to collect sufficient, adequate data for EHR in the near future. Among the proposed procedures, NTUH decides to establish a web-based mobile electronic medication administration record (ME-MAR) system. The system, build based on the service-oriented architecture (SOA) as well as embedded the HL7/XML standard, is installed in the Mobile Nursing Carts. It also implement accompany with the advanced techniques like Asynchronous JavaScript and XML (Ajax) or Web services to enhance the system usability. According to researches, it indicates that medication errors are highly proportion to total medical faults. Therefore, we expect the ME-MAR system can reduce medication errors. In addition, we evaluate ME-MAR can assist nurses or healthcare practitioners to administer, manage medication properly. This successful experience of developing the NTUH ME-MAR system can be easily applied to other related system. Meanwhile, the SOA architecture of the system can also be seamless integrated to NTUH or other HIS system.

  4. An ODA-based coder/decoder for multimedia medical documents.

    PubMed Central

    Marti, V.; Navio, J.; Salvador, C. H.; Pulido, N.; Muñoz, A.; Gonzalez, M. A.; Dueñas, A.

    1993-01-01

    This paper describes the prototype of a coder/decoder based on the Open Document Architecture (ODA) standard for management of medical documents, as well as the working environment in which it has been developed. The prototype has been assessed in an X-Windows-equipped workstation with a relational database containing patient folders (text and still images) from the departmental information system of the liver transplantation unit. PMID:8130599

  5. Distributed search engine architecture based on topic specific searches

    NASA Astrophysics Data System (ADS)

    Abudaqqa, Yousra; Patel, Ahmed

    2015-05-01

    Indisputably, search engines (SEs) abound. The monumental growth of users performing online searches on the Web is a contending issue in the contemporary world nowadays. For example, there are tens of billions of searches performed everyday, which typically offer the users many irrelevant results which are time consuming and costly to the user. Based on the afore-going problem it has become a herculean task for existing Web SEs to provide complete, relevant and up-to-date information response to users' search queries. To overcome this problem, we developed the Distributed Search Engine Architecture (DSEA), which is a new means of smart information query and retrieval of the World Wide Web (WWW). In DSEAs, multiple autonomous search engines, owned by different organizations or individuals, cooperate and act as a single search engine. This paper includes the work reported in this research focusing on development of DSEA, based on topic-specific specialised search engines. In DSEA, the results to specific queries could be provided by any of the participating search engines, for which the user is unaware of. The important design goal of using topic-specific search engines in the research is to build systems that can effectively be used by larger number of users simultaneously. Efficient and effective usage with good response is important, because it involves leveraging the vast amount of searched data from the World Wide Web, by categorising it into condensed focused topic -specific results that meet the user's queries. This design model and the development of the DSEA adopt a Service Directory (SD) to route queries towards topic-specific document hosting SEs. It displays the most acceptable performance which is consistent with the requirements of the users. The evaluation results of the model return a very high priority score which is associated with each frequency of a keyword.

  6. Science Possibilities Enabled by the Mars Base Camp Human Exploration Architecture

    NASA Astrophysics Data System (ADS)

    Cichan, T.; Murrow, D. W.; Jolly, S. D.; Bierhaus, E. B.; Clark, B.

    2017-02-01

    The Mars Base Camp architecture study reveals scientific possibilities enabled by a crewed orbital base camp, and that collaborative human and robotic missions should be part of the vision for Mars exploration by 2050.

  7. Exploration Space Suit Architecture: Destination Environmental-Based Technology Development

    NASA Technical Reports Server (NTRS)

    Hill, Terry R.

    2010-01-01

    This paper picks up where EVA Space Suit Architecture: Low Earth Orbit Vs. Moon Vs. Mars (Hill, Johnson, IEEEAC paper #1209) left off in the development of a space suit architecture that is modular in design and interfaces and could be reconfigured to meet the mission or during any given mission depending on the tasks or destination. This paper will walk though the continued development of a space suit system architecture, and how it should evolve to meeting the future exploration EVA needs of the United States space program. In looking forward to future US space exploration and determining how the work performed to date in the CxP and how this would map to a future space suit architecture with maximum re-use of technology and functionality, a series of thought exercises and analysis have provided a strong indication that the CxP space suit architecture is well postured to provide a viable solution for future exploration missions. Through the destination environmental analysis that is presented in this paper, the modular architecture approach provides the lowest mass, lowest mission cost for the protection of the crew given any human mission outside of low Earth orbit. Some of the studies presented here provide a look and validation of the non-environmental design drivers that will become every-increasingly important the further away from Earth humans venture and the longer they are away. Additionally, the analysis demonstrates a logical clustering of design environments that allows a very focused approach to technology prioritization, development and design that will maximize the return on investment independent of any particular program and provide architecture and design solutions for space suit systems in time or ahead of being required for any particular manned flight program in the future. The new approach to space suit design and interface definition the discussion will show how the architecture is very adaptable to programmatic and funding changes with

  8. Developing a Conceptual Architecture for a Generalized Agent-based Modeling Environment (GAME)

    DTIC Science & Technology

    2008-03-01

    possible. A conceptual architecture for a generalized agent- based modeling environment (GAME) based upon design principles from OR/MS systems was created...conceptual architecture for a generalized agent-based modeling environment (GAME) based upon design principles from OR/MS systems was created that...handle the event, and subsequently form the relevant plans. One of these plans will be selected, and either pushed to the top of the current

  9. Collaborative Concept Mapping in a Web-Based Learning Environment: A Pedagogic Experience in Architectural Education.

    ERIC Educational Resources Information Center

    Madrazo, Leandro; Vidal, Jordi

    2002-01-01

    Describes a pedagogical work, carried out within a school of architecture, using a Web-based learning environment to support collaborative understanding of texts on architectural theory. Explains the use of concept maps, creation of a critical vocabulary, exploration of semantic spaces, and knowledge discovery through navigation. (Author/LRW)

  10. Neutron sources based on medical Linac

    NASA Astrophysics Data System (ADS)

    Costa, M.; Durisi, E.; Monti, V.; Visca, L.; Zanini, A.; Giannini, G.

    2016-11-01

    The paper proposes the study of a novel photo-neutron source based on a medical high-energy electron Linac. Previous studies by the authors already demonstrated the possibility to obtain with this technique a thermal neutron flux of the order of 107 cm-2 s-1 . This paper shows possible Linac's setup and a new photo-converter design to reach a thermal neutron flux around 6×107 cm-2 s-1 , keeping a reasonable high quality of the beam with respect to fast neutron and gamma contaminations.

  11. Architecture-Level Dependability Analysis of a Medical Decision Support System

    SciTech Connect

    Pullum, Laura L; Symons, Christopher T; Patton, Robert M; Beckerman, Barbara G

    2010-01-01

    Recent advances in techniques such as image analysis, text analysis and machine learning have shown great potential to assist physicians in detecting and diagnosing health issues in patients. In this paper, we describe the approach and findings of an architecture-level dependability analysis for a mammography decision support system that incorporates these techniques. The goal of the research described in this paper is to provide an initial understanding of the dependability issues, particularly the potential failure modes and severity, in order to identify areas of potential high risk. The results will guide design decisions and provide the basis of a dependability and performance evaluation program.

  12. Synthetic Adhesive Attachment Discs based on Spider Pyriform Silk Architecture

    NASA Astrophysics Data System (ADS)

    Jain, Dharamdeep; Sahni, Vasav; Dhinojwala, Ali

    2014-03-01

    Among the variety of silks produced by spiders, pyriform silk is used in conjunction with the dragline silk to attach webs to different surfaces. Cob weaver spiders employ different architectural patterns to utilize the pyriform silk and form attachment joints with each pattern having a characteristic adhesive performance. The staple pin architecture is a one of the strongest attachment designs employed by spiders to attach their webs. Here we use a synthetic approach to create the a similar patterned architecture attachment discs on aluminum substrate using thermoplastic polyurethane. Measurable pull off forces are generated when the synthetic discs are peeled off a surface. This innovative adhesive strategy can be a source of design in various biomedical applications. Financial Support from National Science Foundation.

  13. Neural architecture design based on extreme learning machine.

    PubMed

    Bueno-Crespo, Andrés; García-Laencina, Pedro J; Sancho-Gómez, José-Luis

    2013-12-01

    Selection of the optimal neural architecture to solve a pattern classification problem entails to choose the relevant input units, the number of hidden neurons and its corresponding interconnection weights. This problem has been widely studied in many research works but their solutions usually involve excessive computational cost in most of the problems and they do not provide a unique solution. This paper proposes a new technique to efficiently design the MultiLayer Perceptron (MLP) architecture for classification using the Extreme Learning Machine (ELM) algorithm. The proposed method provides a high generalization capability and a unique solution for the architecture design. Moreover, the selected final network only retains those input connections that are relevant for the classification task. Experimental results show these advantages.

  14. Practical Application of Model-based Programming and State-based Architecture to Space Missions

    NASA Technical Reports Server (NTRS)

    Horvath, Gregory A.; Ingham, Michel D.; Chung, Seung; Martin, Oliver; Williams, Brian

    2006-01-01

    Innovative systems and software engineering solutions are required to meet the increasingly challenging demands of deep-space robotic missions. While recent advances in the development of an integrated systems and software engineering approach have begun to address some of these issues, they are still at the core highly manual and, therefore, error-prone. This paper describes a task aimed at infusing MIT's model-based executive, Titan, into JPL's Mission Data System (MDS), a unified state-based architecture, systems engineering process, and supporting software framework. Results of the task are presented, including a discussion of the benefits and challenges associated with integrating mature model-based programming techniques and technologies into a rigorously-defined domain specific architecture.

  15. Supporting diagnosis and treatment in medical care based on Big Data processing.

    PubMed

    Lupşe, Oana-Sorina; Crişan-Vida, Mihaela; Stoicu-Tivadar, Lăcrămioara; Bernard, Elena

    2014-01-01

    With information and data in all domains growing every day, it is difficult to manage and extract useful knowledge for specific situations. This paper presents an integrated system architecture to support the activity in the Ob-Gin departments with further developments in using new technology to manage Big Data processing - using Google BigQuery - in the medical domain. The data collected and processed with Google BigQuery results from different sources: two Obstetrics & Gynaecology Departments, the TreatSuggest application - an application for suggesting treatments, and a home foetal surveillance system. Data is uploaded in Google BigQuery from Bega Hospital Timişoara, Romania. The analysed data is useful for the medical staff, researchers and statisticians from public health domain. The current work describes the technological architecture and its processing possibilities that in the future will be proved based on quality criteria to lead to a better decision process in diagnosis and public health.

  16. MediAgent: a WWW-based scalable and self-learning medical search engine.

    PubMed Central

    Tay, J.; Ke, S.; Lun, K. C.

    1998-01-01

    Searching for medical information on the Internet can be tedious and frustrating due to the number of irrelevant entries returned from generic search engines. We have developed MediAgent, a scalable search engine that aims to deliver a web-based medical search solution which is focused, exhaustive and able to keep improving its databases. The software package can run off a single low-end system and be scaled into a client-server, distributed computing architecture for high-end needs. This scalable architecture boosts MediAgent's handling capacity to tens of millions of web pages. In addition to large volume handling, MediAgent is designed to be manageable. All subsystems are not only highly configurable, but also support remote, interactive management and monitoring by the system administrator. PMID:9929289

  17. [Looking for evidence-based medical informatics].

    PubMed

    Coiera, Enrico

    2016-03-01

    e-Health is experiencing a difficult time. On the one side, the forecast is for a bright digital health future created by precision medicine and smart devices. On the other hand, most large scale e-health projects struggle to make a difference and are often controversial. Both futures fail because they are not evidence-based. Medical informatics should follow the example of evidence-based medicine, i.e. conduct rigorous research that gives us evidence to solve real world problems, synthesise that evidence and then apply it strictly. We already have the tools for creating a different universe. What we need is evidence, will, a culture of learning, and hard work.

  18. Extracting clinical information to support medical decision based on standards.

    PubMed

    Gomoi, Valentin; Vida, Mihaela; Stoicu-Tivadar, Lăcrămioara; Stoicu-Tivadar, Vasile

    2011-01-01

    The paper presents a method connecting medical databases to a medical decision system, and describes a service created to extract the necessary information that is transferred based on standards. The medical decision can be improved based on many inputs from different medical locations. The developed solution is described for a concrete case concerning the management for chronic pelvic pain, based on the information retrieved from diverse healthcare databases.

  19. Developing a Systematic Architecture Approach for Designing an Enhanced Electronic Medical Record (EEMR) System

    ERIC Educational Resources Information Center

    Aldukheil, Maher A.

    2013-01-01

    The Healthcare industry is characterized by its complexity in delivering care to the patients. Accordingly, healthcare organizations adopt and implement Information Technology (IT) solutions to manage complexity, improve quality of care, and transform to a fully integrated and digitized environment. Electronic Medical Records (EMR), which is…

  20. Architecture-Based Reliability Analysis of Web Services

    ERIC Educational Resources Information Center

    Rahmani, Cobra Mariam

    2012-01-01

    In a Service Oriented Architecture (SOA), the hierarchical complexity of Web Services (WS) and their interactions with the underlying Application Server (AS) create new challenges in providing a realistic estimate of WS performance and reliability. The current approaches often treat the entire WS environment as a black-box. Thus, the sensitivity…

  1. Exploratory Inquiry: Disparate Air Force Base Area Network Architectures

    DTIC Science & Technology

    2005-03-01

    Lieutenant Jamie Sharkey conducted a thesis on the key issues pertaining to Air Force enterprise architecture management. Discussion of...experience in fixed and tactical communications. His first duty station was McGuire AFB, New Jersey followed by assignments to Spangdahlem AB, Germany; the

  2. A CSP-Based Agent Modeling Framework for the Cougaar Agent-Based Architecture

    NASA Technical Reports Server (NTRS)

    Gracanin, Denis; Singh, H. Lally; Eltoweissy, Mohamed; Hinchey, Michael G.; Bohner, Shawn A.

    2005-01-01

    Cognitive Agent Architecture (Cougaar) is a Java-based architecture for large-scale distributed agent-based applications. A Cougaar agent is an autonomous software entity with behaviors that represent a real-world entity (e.g., a business process). A Cougaar-based Model Driven Architecture approach, currently under development, uses a description of system's functionality (requirements) to automatically implement the system in Cougaar. The Communicating Sequential Processes (CSP) formalism is used for the formal validation of the generated system. Two main agent components, a blackboard and a plugin, are modeled as CSP processes. A set of channels represents communications between the blackboard and individual plugins. The blackboard is represented as a CSP process that communicates with every agent in the collection. The developed CSP-based Cougaar modeling framework provides a starting point for a more complete formal verification of the automatically generated Cougaar code. Currently it is used to verify the behavior of an individual agent in terms of CSP properties and to analyze the corresponding Cougaar society.

  3. A VLSI Architecture for Output Probability Computations of HMM-Based Recognition Systems with Store-Based Block Parallel Processing

    NASA Astrophysics Data System (ADS)

    Nakamura, Kazuhiro; Yamamoto, Masatoshi; Takagi, Kazuyoshi; Takagi, Naofumi

    In this paper, a fast and memory-efficient VLSI architecture for output probability computations of continuous Hidden Markov Models (HMMs) is presented. These computations are the most time-consuming part of HMM-based recognition systems. High-speed VLSI architectures with small registers and low-power dissipation are required for the development of mobile embedded systems with capable human interfaces. We demonstrate store-based block parallel processing (StoreBPP) for output probability computations and present a VLSI architecture that supports it. When the number of HMM states is adequate for accurate recognition, compared with conventional stream-based block parallel processing (StreamBPP) architectures, the proposed architecture requires fewer registers and processing elements and less processing time. The processing elements used in the StreamBPP architecture are identical to those used in the StoreBPP architecture. From a VLSI architectural viewpoint, a comparison shows the efficiency of the proposed architecture through efficient use of registers for storing input feature vectors and intermediate results during computation.

  4. Simulation-based medical education in pediatrics.

    PubMed

    Lopreiato, Joseph O; Sawyer, Taylor

    2015-01-01

    The use of simulation-based medical education (SBME) in pediatrics has grown rapidly over the past 2 decades and is expected to continue to grow. Similar to other instructional formats used in medical education, SBME is an instructional methodology that facilitates learning. Successful use of SBME in pediatrics requires attention to basic educational principles, including the incorporation of clear learning objectives. To facilitate learning during simulation the psychological safety of the participants must be ensured, and when done correctly, SBME is a powerful tool to enhance patient safety in pediatrics. Here we provide an overview of SBME in pediatrics and review key topics in the field. We first review the tools of the trade and examine various types of simulators used in pediatric SBME, including human patient simulators, task trainers, standardized patients, and virtual reality simulation. Then we explore several uses of simulation that have been shown to lead to effective learning, including curriculum integration, feedback and debriefing, deliberate practice, mastery learning, and range of difficulty and clinical variation. Examples of how these practices have been successfully used in pediatrics are provided. Finally, we discuss the future of pediatric SBME. As a community, pediatric simulation educators and researchers have been a leading force in the advancement of simulation in medicine. As the use of SBME in pediatrics expands, we hope this perspective will serve as a guide for those interested in improving the state of pediatric SBME.

  5. Local alignment tool based on Hadoop framework and GPU architecture.

    PubMed

    Hung, Che-Lun; Hua, Guan-Jie

    2014-01-01

    With the rapid growth of next generation sequencing technologies, such as Slex, more and more data have been discovered and published. To analyze such huge data the computational performance is an important issue. Recently, many tools, such as SOAP, have been implemented on Hadoop and GPU parallel computing architectures. BLASTP is an important tool, implemented on GPU architectures, for biologists to compare protein sequences. To deal with the big biology data, it is hard to rely on single GPU. Therefore, we implement a distributed BLASTP by combining Hadoop and multi-GPUs. The experimental results present that the proposed method can improve the performance of BLASTP on single GPU, and also it can achieve high availability and fault tolerance.

  6. Task-Based Crowd Simulation for Heterogeneous Architectures

    SciTech Connect

    Perez, Hugo; Rudomin, Isaac; Ayguade, Eduard

    2016-01-01

    Industry trends in the coming years imply the availability of cluster computing with hundreds to thousands of cores per chip, as well as the use of accelerators. Programming presents a challenge due to this heterogeneous architecture; thus, using novel programming models that facilitate this process is necessary. In this chapter, the case of simulation and visualization of crowds is presented. The authors analyze and compare the use of two programming models: OmpSs and CUDA. OmpSs allows to take advantage of all the resources available per node by combining the CPU and GPU while automatically taking care of memory management, scheduling, communications and synchronization. Experimental results obtained from Fermi, Kepler and Maxwell GPU architectures are presented, and the different modes used for visualizing the results are described, as well.

  7. An Agent-Based Architecture for Generating Interactive Stories

    DTIC Science & Technology

    2002-09-01

    Mateas, 1997], [Blumberg, 1996], [Hayes-Roth et al., 1996] and [Rickel et al., 2001]. However, the body of work on developing systems where the...without detailed planning. The underlying agent architecture centers around a mind- body design. The mind is the implementation of a social-psychological...external inputs and stimuli, controls the agents decisions and provides input to the body . The body is the expression of the actions selected by

  8. Case-Based Tutoring from a Medical Knowledge Base

    PubMed Central

    Chin, Homer L.

    1988-01-01

    The past decade has seen the emergence of programs that make use of large knowledge bases to assist physicians in diagnosis within the general field of internal medicine. One such program, Internist-I, contains knowledge about over 600 diseases, covering a significant proportion of internal medicine. This paper describes the process of converting a subset of this knowledge base--in the area of cardiovascular diseases--into a probabilistic format, and the use of this resulting knowledge base to teach medical diagnostic knowledge. The system (called KBSimulator--for Knowledge-Based patient Simulator) generates simulated patient cases and uses these cases as a focal point from which to teach medical knowledge. It interacts with the student in a mixed-initiative fashion, presenting patients for the student to diagnose, and allowing the student to obtain further information on his/her own initiative in the context of that patient case. The system scores the student, and uses these scores to form a rudimentary model of the student. This resulting model of the student is then used to direct the generation of subsequent patient cases. This project demonstrates the feasibility of building an intelligent, flexible instructional system that uses a knowledge base constructed primarily for medical diagnosis.

  9. An Indoor Monitoring System for Ambient Assisted Living Based on Internet of Things Architecture

    PubMed Central

    Marques, Gonçalo; Pitarma, Rui

    2016-01-01

    The study of systems and architectures for ambient assisted living (AAL) is undoubtedly a topic of great relevance given the aging of the world population. The AAL technologies are designed to meet the needs of the aging population in order to maintain their independence as long as possible. As people typically spend more than 90% of their time in indoor environments, indoor air quality (iAQ) is perceived as an imperative variable to be controlled for the inhabitants’ wellbeing and comfort. Advances in networking, sensors, and embedded devices have made it possible to monitor and provide assistance to people in their homes. The continuous technological advancements make it possible to build smart objects with great capabilities for sensing and connecting several possible advancements in ambient assisted living systems architectures. Indoor environments are characterized by several pollutant sources. Most of the monitoring frameworks instantly accessible are exceptionally costly and only permit the gathering of arbitrary examples. iAQ is an indoor air quality system based on an Internet of Things paradigm that incorporates in its construction Arduino, ESP8266, and XBee technologies for processing and data transmission and micro sensors for data acquisition. It also allows access to data collected through web access and through a mobile application in real time, and this data can be accessed by doctors in order to support medical diagnostics. Five smaller scale sensors of natural parameters (air temperature, moistness, carbon monoxide, carbon dioxide, and glow) were utilized. Different sensors can be included to check for particular contamination. The results reveal that the system can give a viable indoor air quality appraisal in order to anticipate technical interventions for improving indoor air quality. Indeed indoor air quality might be distinctively contrasted with what is normal for a quality living environment. PMID:27869682

  10. An Indoor Monitoring System for Ambient Assisted Living Based on Internet of Things Architecture.

    PubMed

    Marques, Gonçalo; Pitarma, Rui

    2016-11-17

    The study of systems and architectures for ambient assisted living (AAL) is undoubtedly a topic of great relevance given the aging of the world population. The AAL technologies are designed to meet the needs of the aging population in order to maintain their independence as long as possible. As people typically spend more than 90% of their time in indoor environments, indoor air quality (iAQ) is perceived as an imperative variable to be controlled for the inhabitants' wellbeing and comfort. Advances in networking, sensors, and embedded devices have made it possible to monitor and provide assistance to people in their homes. The continuous technological advancements make it possible to build smart objects with great capabilities for sensing and connecting several possible advancements in ambient assisted living systems architectures. Indoor environments are characterized by several pollutant sources. Most of the monitoring frameworks instantly accessible are exceptionally costly and only permit the gathering of arbitrary examples. iAQ is an indoor air quality system based on an Internet of Things paradigm that incorporates in its construction Arduino, ESP8266, and XBee technologies for processing and data transmission and micro sensors for data acquisition. It also allows access to data collected through web access and through a mobile application in real time, and this data can be accessed by doctors in order to support medical diagnostics. Five smaller scale sensors of natural parameters (air temperature, moistness, carbon monoxide, carbon dioxide, and glow) were utilized. Different sensors can be included to check for particular contamination. The results reveal that the system can give a viable indoor air quality appraisal in order to anticipate technical interventions for improving indoor air quality. Indeed indoor air quality might be distinctively contrasted with what is normal for a quality living environment.

  11. WebMIRS: web-based medical information retrieval system

    NASA Astrophysics Data System (ADS)

    Long, L. Rodney; Pillemer, Stanley R.; Lawrence, Reva C.; Goh, Gin-Hua; Neve, Leif; Thoma, George R.

    1997-12-01

    At the Lister Hill National Center for Biomedical Communications, a research and development division of the National Library of Medicine (NLM), we are developing a prototype multimedia database system to provide World Wide Web access to biomedical databases. WebMIRS (Web-based Medical Information Retrieval System) will allow access to databases containing text and images and will allow database query by standard SQL, by image content, or by a combination of the two. The system is being developed in the form of Java applets, which will communicate with the Informix DBMS on an NLM Sun workstation running the Solaris operating system. The system architecture will allow access from any hardware platform, which supports a Java-enabled Web browser, such as Netscape or Internet Explorer. Initial databases will include data from two national health surveys conducted by the National Center for Health Statistics (NCHS), and will include x-ray images from those surveys. In addition to describing in- house research in database access systems, this paper describes ongoing work toward querying by image content. Image content search capability will include capability to search for x-ray images similar to an input image with respect to vertebral morphometry used to characterize features such as fractures and disc space narrowing.

  12. Dynamic DICOM configuration in a service-oriented medical device architecture.

    PubMed

    Schlamelcher, Jan; Onken, Michael; Eichelberg, Marco; Hein, Andreas

    2015-08-01

    A surgical intervention raises additional requirements to a medical device network, be it security concerns or the demand for just-in-time integration of an additional devices. The German national flagship project OR.NET aims to satisfy these requirements by defining, implementing and validating an integration solution for safe and dynamic networking. This work presents an approach to incorporate imaging related medical devices into a dynamic plug and play operating room (OR) network utilizing the existing Digital Imaging and Communications in Medicine (DICOM) protocol. The presented approach was created as part of the OR.NET project to realize the integration of DICOM devices into the developed infrastructure, both in regard to newly created DICOM devices with direct support of the OR.NET protocol and the integration of existing DICOM devices (e.g. image archives) employing a gateway. Preliminary evaluation results indicate that the approach is viable and that no critical transmission delays are introduced by the prototypical gateway implementation.

  13. [Consistent presentation of medical images based on CPI integration profile].

    PubMed

    Jiang, Tao; An, Ji-ye; Chen, Zhong-yong; Lu, Xu-dong; Duan, Hui-long

    2007-11-01

    Because of different display parameters and other factors, digital medical images present different display states in different section offices of a hospital. Based on CPI integration profile of IHE, this paper implements the consistent presentation of medical images, and it is helpful for doctors to carry out medical treatments of teamwork.

  14. RRAM-based parallel computing architecture using k-nearest neighbor classification for pattern recognition.

    PubMed

    Jiang, Yuning; Kang, Jinfeng; Wang, Xinan

    2017-03-24

    Resistive switching memory (RRAM) is considered as one of the most promising devices for parallel computing solutions that may overcome the von Neumann bottleneck of today's electronic systems. However, the existing RRAM-based parallel computing architectures suffer from practical problems such as device variations and extra computing circuits. In this work, we propose a novel parallel computing architecture for pattern recognition by implementing k-nearest neighbor classification on metal-oxide RRAM crossbar arrays. Metal-oxide RRAM with gradual RESET behaviors is chosen as both the storage and computing components. The proposed architecture is tested by the MNIST database. High speed (~100 ns per example) and high recognition accuracy (97.05%) are obtained. The influence of several non-ideal device properties is also discussed, and it turns out that the proposed architecture shows great tolerance to device variations. This work paves a new way to achieve RRAM-based parallel computing hardware systems with high performance.

  15. Developing image-based electronic patient records for collaborative medical applications

    NASA Astrophysics Data System (ADS)

    Zhang, Jianguo; Sun, Jianyong; Yong, Yuanyuan; Chen, Xiaomeng; Yu, Fenghai; Zhang, Xiaoyan; Lian, Ping; Sun, Kun; Huang, H. K.

    2004-04-01

    We developed a Web-based system to interactively display image-based electronic patient records (EPR) for intranet and Internet collaborative medical applications. The system consists of four major components: EPR DICOM gateway (EPR-GW), Image-based EPR repository server (EPR-Server), Web Server and EPR DICOM viewer (EPR-Viewer). We have successfully used this system two times for the teleconsultation on Severe acute respiratory syndrome (SARS) in Shanghai Xinhua Hospital and Shanghai Infection Hospital. During the consultation, both the physicians in infection control area and the experts outside the control area could interactively study, manipulate and navigate the EPR of the SARS patients to make more precise diagnosis on images with this system assisting. This presentation gave a new approach to create and manage image-based EPR from actual patient records, and also presented a way to use Web technology and DICOM standard to build an open architecture for collaborative medical applications.

  16. Developing an Evaluation Method for Middleware-Based Software Architectures of Airborne Mission Systems

    DTIC Science & Technology

    2007-07-01

    documented using an architecture knowledge management tool also developed at NICTA. 31 DSTO-TR-2204 9. References [Ali- Babar & Gorton 2004] [Ali... Babar et al. 2005] [Allen et al. 2002] [Bachmann et al. 2003] [Barbacci et al. 1995] [Bass et al. 2003] [Basse/al. 2001] [Bengstsson et al. 2004...Boehm&In 1996] [CORBA 2006] [Clements et al. 2001] Ali- Babar , M. & Gorton, I. (2004) Comparison of Scenario-Based Software Architecture

  17. Security mechanism based on Hospital Authentication Server for secure application of implantable medical devices.

    PubMed

    Park, Chang-Seop

    2014-01-01

    After two recent security attacks against implantable medical devices (IMDs) have been reported, the privacy and security risks of IMDs have been widely recognized in the medical device market and research community, since the malfunctioning of IMDs might endanger the patient's life. During the last few years, a lot of researches have been carried out to address the security-related issues of IMDs, including privacy, safety, and accessibility issues. A physician accesses IMD through an external device called a programmer, for diagnosis and treatment. Hence, cryptographic key management between IMD and programmer is important to enforce a strict access control. In this paper, a new security architecture for the security of IMDs is proposed, based on a 3-Tier security model, where the programmer interacts with a Hospital Authentication Server, to get permissions to access IMDs. The proposed security architecture greatly simplifies the key management between IMDs and programmers. Also proposed is a security mechanism to guarantee the authenticity of the patient data collected from IMD and the nonrepudiation of the physician's treatment based on it. The proposed architecture and mechanism are analyzed and compared with several previous works, in terms of security and performance.

  18. Security Mechanism Based on Hospital Authentication Server for Secure Application of Implantable Medical Devices

    PubMed Central

    2014-01-01

    After two recent security attacks against implantable medical devices (IMDs) have been reported, the privacy and security risks of IMDs have been widely recognized in the medical device market and research community, since the malfunctioning of IMDs might endanger the patient's life. During the last few years, a lot of researches have been carried out to address the security-related issues of IMDs, including privacy, safety, and accessibility issues. A physician accesses IMD through an external device called a programmer, for diagnosis and treatment. Hence, cryptographic key management between IMD and programmer is important to enforce a strict access control. In this paper, a new security architecture for the security of IMDs is proposed, based on a 3-Tier security model, where the programmer interacts with a Hospital Authentication Server, to get permissions to access IMDs. The proposed security architecture greatly simplifies the key management between IMDs and programmers. Also proposed is a security mechanism to guarantee the authenticity of the patient data collected from IMD and the nonrepudiation of the physician's treatment based on it. The proposed architecture and mechanism are analyzed and compared with several previous works, in terms of security and performance. PMID:25276797

  19. Rapid architecture alternative modeling (RAAM): A framework for capability-based analysis of system of systems architectures

    NASA Astrophysics Data System (ADS)

    Iacobucci, Joseph V.

    problem domain by establishing an effective means to communicate the semantics from the RAAM framework. These techniques make it possible to include diverse multi-metric models within the RAAM framework in addition to system and operational level trades. A canonical example was used to explore the uses of the methodology. The canonical example contains all of the features of a full system of systems architecture analysis study but uses fewer tasks and systems. Using RAAM with the canonical example it was possible to consider both system and operational level trades in the same analysis. Once the methodology had been tested with the canonical example, a Suppression of Enemy Air Defenses (SEAD) capability model was developed. Due to the sensitive nature of analyses on that subject, notional data was developed. The notional data has similar trends and properties to realistic Suppression of Enemy Air Defenses data. RAAM was shown to be traceable and provided a mechanism for a unified treatment of a variety of metrics. The SEAD capability model demonstrated lower computer runtimes and reduced model creation complexity as compared to methods currently in use. To determine the usefulness of the implementation of the methodology on current computing hardware, RAAM was tested with system of system architecture studies of different sizes. This was necessary since system of systems may be called upon to accomplish thousands of tasks. It has been clearly demonstrated that RAAM is able to enumerate and evaluate the types of large, complex design spaces usually encountered in capability based design, oftentimes providing the ability to efficiently search the entire decision space. The core algorithms for generation and evaluation of alternatives scale linearly with expected problem sizes. The SEAD capability model outputs prompted the discovery a new issue, the data storage and manipulation requirements for an analysis. Two strategies were developed to counter large data sizes, the use

  20. Argument-based medical ethics: a formal tool for critically appraising the normative medical ethics literature.

    PubMed

    McCullough, Laurence B; Coverdale, John H; Chervenak, Frank A

    2004-10-01

    Although there are critical appraisal tools for other genres of the medical literature, there currently is no formal tool for physicians to use in their critical appraisal of the normative medical ethics literature. We present a formal assessment tool for the critical appraisal of the normative medical ethics literature that incorporates the intellectual standards of argument-based medical ethics and evidence-based medicine. We draw on the intellectual standards of argument-based ethics, ethical analysis and argument, and the literature on evidence-based medicine. The tool involves 4 questions about normative medical ethics papers: (1) Does the article address a focused ethics question? (2) Are the arguments that support the results of the article valid? (3) What are the results? (4) Will the results help me in clinical practice? Obstetrician-gynecologists can use this tool to appraise the normative literature of ethics in obstetrics and gynecology formally.

  1. Architecture and System Engineering Development Study of Space-Based Satellite Networks for NASA Missions

    NASA Technical Reports Server (NTRS)

    Ivancic, William D.

    2003-01-01

    Traditional NASA missions, both near Earth and deep space, have been stovepipe in nature and point-to-point in architecture. Recently, NASA and others have conceptualized missions that required space-based networking. The notion of networks in space is a drastic shift in thinking and requires entirely new architectures, radio systems (antennas, modems, and media access), and possibly even new protocols. A full system engineering approach for some key mission architectures will occur that considers issues such as the science being performed, stationkeeping, antenna size, contact time, data rates, radio-link power requirements, media access techniques, and appropriate networking and transport protocols. This report highlights preliminary architecture concepts and key technologies that will be investigated.

  2. A Low Cost VLSI Architecture for Spike Sorting Based on Feature Extraction with Peak Search

    PubMed Central

    Chang, Yuan-Jyun; Hwang, Wen-Jyi; Chen, Chih-Chang

    2016-01-01

    The goal of this paper is to present a novel VLSI architecture for spike sorting with high classification accuracy, low area costs and low power consumption. A novel feature extraction algorithm with low computational complexities is proposed for the design of the architecture. In the feature extraction algorithm, a spike is separated into two portions based on its peak value. The area of each portion is then used as a feature. The algorithm is simple to implement and less susceptible to noise interference. Based on the algorithm, a novel architecture capable of identifying peak values and computing spike areas concurrently is proposed. To further accelerate the computation, a spike can be divided into a number of segments for the local feature computation. The local features are subsequently merged with the global ones by a simple hardware circuit. The architecture can also be easily operated in conjunction with the circuits for commonly-used spike detection algorithms, such as the Non-linear Energy Operator (NEO). The architecture has been implemented by an Application-Specific Integrated Circuit (ASIC) with 90-nm technology. Comparisons to the existing works show that the proposed architecture is well suited for real-time multi-channel spike detection and feature extraction requiring low hardware area costs, low power consumption and high classification accuracy. PMID:27941631

  3. Developing a competency-based medical education curriculum for the core basic medical sciences in an African Medical School

    PubMed Central

    Olopade, Funmilayo Eniola; Adaramoye, Oluwatosin Adekunle; Raji, Yinusa; Fasola, Abiodun Olubayo; Olapade-Olaopa, Emiola Oluwabunmi

    2016-01-01

    The College of Medicine of the University of Ibadan recently revised its MBBS and BDS curricula to a competency-based medical education method of instruction. This paper reports the process of revising the methods of instruction and assessment in the core basic medical sciences directed at producing medical and dental graduates with a sound knowledge of the subjects sufficient for medical and dental practice and for future postgraduate efforts in the field or related disciplines. The health needs of the community and views of stakeholders in the Ibadan medical and dental schools were determined, and the “old” curriculum was reviewed. This process was directed at identifying the strengths and weaknesses of the old curricula and the newer competences required for modern-day medical/dental practice. The admission criteria and processes and the learning methods of the students were also studied. At the end of the review, an integrated, system-based, community-oriented, person-centered, and competency-driven curriculum was produced and approved for implementation. Four sets of students have been admitted into the curriculum. There have been challenges to the implementation process, but these have been overcome by continuous faculty development and reorientation programs for the nonteaching staff and students. Two sets of students have crossed over to the clinical school, and the consensus among the clinical teachers is that their knowledge and application of the basic medical sciences are satisfactory. The Ibadan medical and dental schools are implementing their competency-based medical education curricula successfully. The modifications to the teaching and assessment of the core basic medical science subjects have resulted in improved learning and performance at the final examinations. PMID:27486351

  4. Architecture Design of Healthcare Software-as-a-Service Platform for Cloud-Based Clinical Decision Support Service

    PubMed Central

    Oh, Sungyoung; Cha, Jieun; Ji, Myungkyu; Kang, Hyekyung; Kim, Seok; Heo, Eunyoung; Han, Jong Soo; Kang, Hyunggoo; Chae, Hoseok; Hwang, Hee

    2015-01-01

    Objectives To design a cloud computing-based Healthcare Software-as-a-Service (SaaS) Platform (HSP) for delivering healthcare information services with low cost, high clinical value, and high usability. Methods We analyzed the architecture requirements of an HSP, including the interface, business services, cloud SaaS, quality attributes, privacy and security, and multi-lingual capacity. For cloud-based SaaS services, we focused on Clinical Decision Service (CDS) content services, basic functional services, and mobile services. Microsoft's Azure cloud computing for Infrastructure-as-a-Service (IaaS) and Platform-as-a-Service (PaaS) was used. Results The functional and software views of an HSP were designed in a layered architecture. External systems can be interfaced with the HSP using SOAP and REST/JSON. The multi-tenancy model of the HSP was designed as a shared database, with a separate schema for each tenant through a single application, although healthcare data can be physically located on a cloud or in a hospital, depending on regulations. The CDS services were categorized into rule-based services for medications, alert registration services, and knowledge services. Conclusions We expect that cloud-based HSPs will allow small and mid-sized hospitals, in addition to large-sized hospitals, to adopt information infrastructures and health information technology with low system operation and maintenance costs. PMID:25995962

  5. A component-based, distributed object services architecture for a clinical workstation.

    PubMed Central

    Chueh, H. C.; Raila, W. F.; Pappas, J. J.; Ford, M.; Zatsman, P.; Tu, J.; Barnett, G. O.

    1996-01-01

    Attention to an architectural framework in the development of clinical applications can promote reusability of both legacy systems as well as newly designed software. We describe one approach to an architecture for a clinical workstation application which is based on a critical middle tier of distributed object-oriented services. This tier of network-based services provides flexibility in the creation of both the user interface and the database tiers. We developed a clinical workstation for ambulatory care using this architecture, defining a number of core services including those for vocabulary, patient index, documents, charting, security, and encounter management. These services can be implemented through proprietary or more standard distributed object interfaces such as CORBA and OLE. Services are accessed over the network by a collection of user interface components which can be mixed and matched to form a variety of interface styles. These services have also been reused with several applications based on World Wide Web browser interfaces. PMID:8947744

  6. A VLSI Architecture with Multiple Fast Store-Based Block Parallel Processing for Output Probability and Likelihood Score Computations in HMM-Based Isolated Word Recognition

    NASA Astrophysics Data System (ADS)

    Nakamura, Kazuhiro; Shimazaki, Ryo; Yamamoto, Masatoshi; Takagi, Kazuyoshi; Takagi, Naofumi

    This paper presents a memory-efficient VLSI architecture for output probability computations (OPCs) of continuous hidden Markov models (HMMs) and likelihood score computations (LSCs). These computations are the most time consuming part of HMM-based isolated word recognition systems. We demonstrate multiple fast store-based block parallel processing (MultipleFastStoreBPP) for OPCs and LSCs and present a VLSI architecture that supports it. Compared with conventional fast store-based block parallel processing (FastStoreBPP) and stream-based block parallel processing (StreamBPP) architectures, the proposed architecture requires fewer registers and less processing time. The processing elements (PEs) used in the FastStoreBPP and StreamBPP architectures are identical to those used in the MultipleFastStoreBPP architecture. From a VLSI architectural viewpoint, a comparison shows that the proposed architecture is an improvement over the others, through efficient use of PEs and registers for storing input feature vectors.

  7. Rule-based graph theory to enable exploration of the space system architecture design space

    NASA Astrophysics Data System (ADS)

    Arney, Dale Curtis

    network flow problems in the past, where nodes represent physical locations and edges represent the means by which information or vehicles travel between those locations. In space system architecting, expressing the physical locations (low-Earth orbit, low-lunar orbit, etc.) and steady states (interplanetary trajectory) as nodes and the different means of moving between the nodes (propulsive maneuvers, etc.) as edges formulates a mathematical representation of this design space. The selection of a given system architecture using graph theory entails defining the paths that the systems take through the space system architecture graph. A path through the graph is defined as a list of edges that are traversed, which in turn defines functions performed by the system. A structure to compactly represent this information is a matrix, called the system map, in which the column indices are associated with the systems that exist and row indices are associated with the edges, or functions, to which each system has access. Several contributions have been added to the state of the art in space system architecture analysis. The framework adds the capability to rapidly explore the design space without the need to limit trade options or the need for user interaction during the exploration process. The unique mathematical representation of a system architecture, through the use of the adjacency, incidence, and system map matrices, enables automated design space exploration using stochastic optimization processes. The innovative rule-based graph traversal algorithm ensures functional feasibility of each system architecture that is analyzed, and the automatic generation of the system hierarchy eliminates the need for the user to manually determine the relationships between systems during or before the design space exploration process. Finally, the rapid evaluation of system architectures for various mission types enables analysis of the system architecture design space for multiple

  8. A Service-Oriented Healthcare Message Alerting Architecture in an Asia Medical Center: A Case Study

    PubMed Central

    Cheng, Po-Hsun; Lai, Feipei; Lai, Jin-Shin

    2009-01-01

    This paper illustrates how our development team has used some information technologies to let physicians obtain an instant abnormal laboratory result report for critical patient care services. We have implemented a healthcare message alerting system (HMAS) on a healthcare short message service (HSMS) engine and the distributed healthcare-oriented service environment (DiHOSE) in the National Taiwan University Hospital (NTUH). The HSMS engine has a general interface for all applications which could easily send any kind of alerting messages. Fundamentally, the DiHOSE uses HL7 standard formats to process the information exchange behaviors and can be flexibly extended for reasonable user requirements. The disease surveillance subsystem is an integral part of NTUH new hospital information system which is based on DiHOSE and the disease surveillance subsystem would send alerting messages through the HSMS engine. The latest cell phone message alerting subsystem, a case study, in NTUH proved that the DiHOSE could integrate the user required functions without much work. We concluded that both HSMS and DiHOSE can generalize and extend application demands efficiently. PMID:19578465

  9. A privacy authentication scheme based on cloud for medical environment.

    PubMed

    Chen, Chin-Ling; Yang, Tsai-Tung; Chiang, Mao-Lun; Shih, Tzay-Farn

    2014-11-01

    With the rapid development of the information technology, the health care technologies already became matured. Such as electronic medical records that can be easily stored. However, how to get medical resources more convenient is currently concerning issue. In spite of many literatures discussed about medical systems, these literatures should face many security challenges. The most important issue is patients' privacy. Therefore, we propose a privacy authentication scheme based on cloud environment. In our scheme, we use mobile device's characteristics, allowing peoples to use medical resources on the cloud environment to find medical advice conveniently. The digital signature is used to ensure the security of the medical information that is certified by the medical department in our proposed scheme.

  10. Competency-based medical education in two Sub-Saharan African medical schools

    PubMed Central

    Kiguli-Malwadde, Elsie; Olapade-Olaopa, E Oluwabunmi; Kiguli, Sarah; Chen, Candice; Sewankambo, Nelson K; Ogunniyi, Adesola O; Mukwaya, Solome; Omaswa, Francis

    2014-01-01

    Background Relatively little has been written on Medical Education in Sub-Saharan Africa, although there are over 170 medical schools in the region. A number of initiatives have been started to support medical education in the region to improve quality and quantity of medical graduates. These initiatives have led to curricular changes in the region, one of which is the introduction of Competency-Based Medical Education (CBME). Institutional reviews This paper presents two medical schools, Makerere University College of Health Sciences and College of Medicine, University of Ibadan, which successfully implemented CBME. The processes of curriculum revision are described and common themes are highlighted. Both schools used similar processes in developing their CBME curricula, with early and significant stakeholder involvement. Competencies were determined taking into consideration each country’s health and education systems. Final competency domains were similar between the two schools. Both schools established medical education departments to support their new curricula. New teaching methodologies and assessment methods were needed to support CBME, requiring investments in faculty training. Both schools received external funding to support CBME development and implementation. Conclusion CBME has emerged as an important change in medical education in Sub-Saharan Africa with schools adopting it as an approach to transformative medical education. Makerere University and the University of Ibadan have successfully adopted CBME and show that CBME can be implemented even for the low-resourced countries in Africa, supported by external investments to address the human resources gap. PMID:25525404

  11. Two RFID-based solutions for secure inpatient medication administration.

    PubMed

    Yen, Yi-Chung; Lo, Nai-Wei; Wu, Tzong-Chen

    2012-10-01

    Medication error can easily cause serious health damage to inpatients in hospital. Consequently, the whole society has to spend huge amount of extra resources for additional therapies and medication on those affected inpatients. In order to prevent medication errors, secure inpatient medication administration system is required in a hospital. Using RFID technology, such administration system provides automated medication verification for inpatient's medicine doses and generates corresponding medication evidence, which may be audited later for medical dispute. Recently, Peris-Lopez et al. (Int. J. Med. Inform., 2011) proposed an IS-RFID system to enhance inpatient medication safety. Nevertheless, IS-RFID system does not detect the denial of proof attack efficiently and the generated medication evidence cannot defend against counterfeit evidence generated from the hospital. That is, the hospital possesses enough privilege from the design of IS-RFID system to modify generated medication evidence whenever it is necessary. Hence, we design two lightweight RFID-based solutions for secure inpatient medication administration, one for online verification environment and the other for offline validation situation, to achieve system security on evidence generation and provide early detection on denial of proof attack.

  12. Peer-to-Peer JXTA Architecture for Continuing Mobile Medical Education Incorporated in Rural Public Health Centers

    PubMed Central

    Rajasekaran, Rajkumar; Iyengar, Nallani Chackravatula Sriman Narayana

    2013-01-01

    Objectives: Mobile technology helps to improve continuing medical education; this includes all aspects of public health care as well as keeping one’s knowledge up-to-date. The program of continuing medical and health education is intertwined with mobile health technology, which forms an imperative component of national strategies in health. Continuing mobile medical education (CMME) programs are designed to ensure that all medical and health-care professionals stay up-to-date with the knowledge required through mobile JXTA to appraise modernized strategies so as to achieve national goals of health-care information distribution. Methods: In this study, a 20-item questionnaire was distributed to 280 health professionals practicing traditional training learning methodologies (180 nurses, 60 doctors, and 40 health inspectors) in 25 rural hospitals. Among the 83% respondents, 56% are eager to take new learning methodologies as part of their evaluation, which is considered for promotion to higher grades, increments, or as part of their work-related activities. Results: The proposed model was executed in five public health centers in which nurses and health inspectors registered in the JXTA network were referred to the record peer group by administrators. A mobile training program on immunization was conducted through the ADVT, with the lectures delivered on their mobiles. Credits are given after taking the course and completing an evaluation test. The system is faster compared with traditional learning. Conclusion: Medical knowledge management and mobile-streaming application support the CMME system through JXTA. The mobile system includes online lectures and practice quizzes, as well as assignments and interactions with health professionals. Evaluation and assessments are done online and credits certificates are provided based on the score the student obtains. The acceptance of mobile JXTA peer-to-peer learning has created a drastic change in learning methods among

  13. Design and characterization of electron beam focusing for X-ray generation in novel medical imaging architecture

    SciTech Connect

    Bogdan Neculaes, V. Zou, Yun; Zavodszky, Peter; Inzinna, Louis; Zhang, Xi; Conway, Kenneth; Caiafa, Antonio; Frutschy, Kristopher; Waters, William; De Man, Bruno

    2014-05-15

    A novel electron beam focusing scheme for medical X-ray sources is described in this paper. Most vacuum based medical X-ray sources today employ a tungsten filament operated in temperature limited regime, with electrostatic focusing tabs for limited range beam optics. This paper presents the electron beam optics designed for the first distributed X-ray source in the world for Computed Tomography (CT) applications. This distributed source includes 32 electron beamlets in a common vacuum chamber, with 32 circular dispenser cathodes operated in space charge limited regime, where the initial circular beam is transformed into an elliptical beam before being collected at the anode. The electron beam optics designed and validated here are at the heart of the first Inverse Geometry CT system, with potential benefits in terms of improved image quality and dramatic X-ray dose reduction for the patient.

  14. Design and characterization of electron beam focusing for X-ray generation in novel medical imaging architecture.

    PubMed

    Bogdan Neculaes, V; Zou, Yun; Zavodszky, Peter; Inzinna, Louis; Zhang, Xi; Conway, Kenneth; Caiafa, Antonio; Frutschy, Kristopher; Waters, William; De Man, Bruno

    2014-05-01

    A novel electron beam focusing scheme for medical X-ray sources is described in this paper. Most vacuum based medical X-ray sources today employ a tungsten filament operated in temperature limited regime, with electrostatic focusing tabs for limited range beam optics. This paper presents the electron beam optics designed for the first distributed X-ray source in the world for Computed Tomography (CT) applications. This distributed source includes 32 electron beamlets in a common vacuum chamber, with 32 circular dispenser cathodes operated in space charge limited regime, where the initial circular beam is transformed into an elliptical beam before being collected at the anode. The electron beam optics designed and validated here are at the heart of the first Inverse Geometry CT system, with potential benefits in terms of improved image quality and dramatic X-ray dose reduction for the patient.

  15. The directing effect of linking units on building microporous architecture in tetraphenyladmantane-based poly(Schiff base) networks.

    PubMed

    Li, Guiyang; Zhang, Biao; Yan, Jun; Wang, Zhonggang

    2014-02-21

    Tetraphenyladamantane-based porous poly(Schiff base)s with BET surface area (>1000 m(2) g(-1)), CO2 uptake (15 wt%, 273 K/1 bar) and H2 uptake (1.26 wt%, 77 K/1 bar) were synthesized. The structure-directing effect of isomers of phenyl diamines on building porous architecture was investigated.

  16. A cloud-based medical image repository

    NASA Astrophysics Data System (ADS)

    Maeder, Anthony J.; Planitz, Birgit M.; El Rifai, Diaa

    2012-02-01

    Many widely used digital medical image collections have been established but these are generally used as raw data sources without related image analysis toolsets. Providing associated functionality to allow specific types of operations to be performed on these images has proved beneficial in some cases (e.g. brain image registration and atlases). However, toolset development to provide generic image analysis functions on medical images has tended to be ad hoc, with Open Source options proliferating (e.g. ITK). Our Automated Medical Image Collection Annotation (AMICA) system is both an image repository, to which the research community can contribute image datasets, and a search/retrieval system that uses automated image annotation. AMICA was designed for the Windows Azure platform to leverage the flexibility and scalability of the cloud. It is intended that AMICA will expand beyond its initial pilot implementation (for brain CT, MR images) to accommodate a wide range of modalities and anatomical regions. This initiative aims to contribute to advances in clinical research by permitting a broader use and reuse of medical image data than is currently attainable. For example, cohort studies for cases with particular physiological or phenotypical profiles will be able to source and include enough cases to provide high statistical power, allowing more individualised risk factors to be assessed and thus allowing screening and staging processes to be optimised. Also, education, training and credentialing of clinicians in image interpretation, will be more effective because it will be possible to select instances of images with specific visual aspects, or correspond to types of cases where reading performance improvement is desirable.

  17. Towards a State Based Control Architecture for Large Telescopes: Laying a Foundation at the VLT

    NASA Technical Reports Server (NTRS)

    Karban, R.; Kornweibel, N.; Dvorak, D.; Ingham, M.; Wagner, D.

    2011-01-01

    Large telescopes are characterized by a high level of distribution of control-related tasks and will feature diverse data flow patterns and large ranges of sampling frequencies; there will often be no single, fixed server-client relationship between the control tasks. the architecture is also challenged by the task of integrating heterogeneous subsystems which will be delivered by multiple different contractors. Due to the high number of distributed components, the control system needs to effectively detect errors and faults, impede their propagation, and accurately mitigate them in the shortest time possible, enabling the service to be restored. The presented Data-Driven Architecture is based on a decentralized approach with an end-to-end integration of disparate, independently developed software components. These components employ a high-performance standards-based communication middle-ware infrastructure, based on the Data Distribution Service. A set of rules and principles, based on JPL's State Analysis method and architecture, are use to constrain component-to component interactions, where the Control System and System Under Control are clearly separated. State Analysis provide a model-based process for capturing system and software requirements and design, greatly reducing the gap between the requirements on software specified by systems engineers and the implementation by software engineers. The method and architecture has been field tested at the Very Large Telescope, where it has been integrated into an operational system.

  18. Pax permanent Martian base: Space architecture for the first human habitation on Mars, volume 5

    NASA Technical Reports Server (NTRS)

    Huebner-Moths, Janis; Fieber, Joseph P.; Rebholz, Patrick J.; Paruleski, Kerry L.; Moore, Gary T. (Editor)

    1992-01-01

    America at the Threshold: Report of the Synthesis Group on America's Space Exploration Initiative (the 'Synthesis Report,' sometimes called the Stafford Report after its astronaut chair, published in 1991) recommended that NASA explore what it called four 'architectures,' i.e., four different scenarios for habitation on Mars. The Advanced Design Program in Space Architecture at the University of Wisconsin-Milwaukee supported this report and two of its scenarios--'Architecture 1' and 'Architecture 4'--during the spring of 1992. This report investigates the implications of different mission scenarios, the Martian environment, supporting technologies, and especially human factors and environment-behavior considerations for the design of the first permanent Martian base. The report is comprised of sections on mission analysis, implications of the Martian atmosphere and geologic environment, development of habitability design requirements based on environment-behavior and human factors research, and a full design proposed (concept design and design development) for the first permanent Martian base and habitat. The design is presented in terms of a base site plan, master plan based on a Mars direct scenario phased through IOC, and design development details of a complete Martian habitat for 18 crew members including all laboratory, mission control, and crew support spaces.

  19. Healing Medical Architecture

    DTIC Science & Technology

    2007-11-02

    build high-rise buildings, although the technique was already known to them (pre-existence of Babylonian ziggurats, Egyptian pyramids, etc.). They had...utilizing low-rise buildings and open-air activities. According to Greek mythology Apollo, the god of sun and music was the physician of the 12 gods

  20. SMS-Based Medical Diagnostic Telemetry Data Transmission Protocol for Medical Sensors

    PubMed Central

    Townsend, Ben; Abawajy, Jemal; Kim, Tai-Hoon

    2011-01-01

    People with special medical monitoring needs can, these days, be sent home and remotely monitored through the use of data logging medical sensors and a transmission base-station. While this can improve quality of life by allowing the patient to spend most of their time at home, most current technologies rely on hardwired landline technology or expensive mobile data transmissions to transmit data to a medical facility. The aim of this paper is to investigate and develop an approach to increase the freedom of a monitored patient and decrease costs by utilising mobile technologies and SMS messaging to transmit data from patient to medico. To this end, we evaluated the capabilities of SMS and propose a generic communications protocol which can work within the constraints of the SMS format, but provide the necessary redundancy and robustness to be used for the transmission of non-critical medical telemetry from data logging medical sensors. PMID:22163845

  1. Emerging medical informatics with case-based reasoning for aiding clinical decision in multi-agent system.

    PubMed

    Shen, Ying; Colloc, Joël; Jacquet-Andrieu, Armelle; Lei, Kai

    2015-08-01

    This research aims to depict the methodological steps and tools about the combined operation of case-based reasoning (CBR) and multi-agent system (MAS) to expose the ontological application in the field of clinical decision support. The multi-agent architecture works for the consideration of the whole cycle of clinical decision-making adaptable to many medical aspects such as the diagnosis, prognosis, treatment, therapeutic monitoring of gastric cancer. In the multi-agent architecture, the ontological agent type employs the domain knowledge to ease the extraction of similar clinical cases and provide treatment suggestions to patients and physicians. Ontological agent is used for the extension of domain hierarchy and the interpretation of input requests. Case-based reasoning memorizes and restores experience data for solving similar problems, with the help of matching approach and defined interfaces of ontologies. A typical case is developed to illustrate the implementation of the knowledge acquisition and restitution of medical experts.

  2. Content-based management service for medical videos.

    PubMed

    Mendi, Engin; Bayrak, Coskun; Cecen, Songul; Ermisoglu, Emre

    2013-01-01

    Development of health information technology has had a dramatic impact to improve the efficiency and quality of medical care. Developing interoperable health information systems for healthcare providers has the potential to improve the quality and equitability of patient-centered healthcare. In this article, we describe an automated content-based medical video analysis and management service that provides convenience and ease in accessing the relevant medical video content without sequential scanning. The system facilitates effective temporal video segmentation and content-based visual information retrieval that enable a more reliable understanding of medical video content. The system is implemented as a Web- and mobile-based service and has the potential to offer a knowledge-sharing platform for the purpose of efficient medical video content access.

  3. Evolving the Web-Based Distributed SI/PDO Architecture for High-Performance Visualization

    SciTech Connect

    HOLMES,VICTOR P.; LINEBARGER,JOHN M.; MILLER,DAVID J.; VANDEWART,RUTHE LYNN; CROWLEY,CHARLES P.

    2000-08-16

    The Simulation Intranet/Product Database Operator (SI/PDO) project has developed a Web-based distributed object architecture for high performance scientific simulation. A Web-based Java interface guides designers through the design and analysis cycle via solid and analytical modeling, meshing, finite element simulation, and various forms of visualization. The SI/PDO architecture has evolved in steps towards satisfying Sandia's long-term goal of providing an end-to-end set of services for high fidelity full physics simulations in a high-performance, distributed, and distance computing environment. This paper describes the continuing evolution of the architecture to provide high-performance visualization services. Extensions to the SI/PDO architecture allow web access to visualization tools that run on MP systems. This architecture makes these tools more easily accessible by providing web-based interfaces and by shielding the user from the details of these computing environments. The design is a multi-tier architecture, where the Java-based GUI tier runs on a web browser and provides image display and control functions. The computation tier runs on MP machines. The middle tiers provide custom communication with MP machines, remote file selection, remote launching of services, load balancing, and machine selection. The architecture allows middleware of various types (CORBA, COM, RMI, sockets, etc.) to connect the tiers depending upon the situation. Testing of constantly developing visualization tools can be done in an environment where there are only two tiers which both run on desktop machines. This allows fast testing turnaround and does not use compute cycles on high-performance machines. Once the code and interfaces are tested, they are moved to high-performance machines, and new tiers are added to handle the problems of using these machines. Uniform interfaces are used throughout the tiers to allow this flexibility. Experiments test the appropriate level of

  4. A high-throughput readout architecture based on PCI-Express Gen3 and DirectGMA technology

    NASA Astrophysics Data System (ADS)

    Rota, L.; Vogelgesang, M.; Ardila Perez, L. E.; Caselle, M.; Chilingaryan, S.; Dritschler, T.; Zilio, N.; Kopmann, A.; Balzer, M.; Weber, M.

    2016-02-01

    Modern physics experiments produce multi-GB/s data rates. Fast data links and high performance computing stages are required for continuous data acquisition and processing. Because of their intrinsic parallelism and computational power, GPUs emerged as an ideal solution to process this data in high performance computing applications. In this paper we present a high-throughput platform based on direct FPGA-GPU communication. The architecture consists of a Direct Memory Access (DMA) engine compatible with the Xilinx PCI-Express core, a Linux driver for register access, and high- level software to manage direct memory transfers using AMD's DirectGMA technology. Measurements with a Gen3 x8 link show a throughput of 6.4 GB/s for transfers to GPU memory and 6.6 GB/s to system memory. We also assess the possibility of using the architecture in low latency systems: preliminary measurements show a round-trip latency as low as 1 μs for data transfers to system memory, while the additional latency introduced by OpenCL scheduling is the current limitation for GPU based systems. Our implementation is suitable for real-time DAQ system applications ranging from photon science and medical imaging to High Energy Physics (HEP) systems.

  5. A competency-based longitudinal core curriculum in medical neuroscience.

    PubMed

    Merlin, Lisa R; Horak, Holli A; Milligan, Tracey A; Kraakevik, Jeff A; Ali, Imran I

    2014-07-29

    Current medical educational theory encourages the development of competency-based curricula. The Accreditation Council for Graduate Medical Education's 6 core competencies for resident education (medical knowledge, patient care, professionalism, interpersonal and communication skills, practice-based learning, and systems-based practice) have been embraced by medical schools as the building blocks necessary for becoming a competent licensed physician. Many medical schools are therefore changing their educational approach to an integrated model in which students demonstrate incremental acquisition and mastery of all competencies as they progress through medical school. Challenges to medical schools include integration of preclinical and clinical studies as well as development of learning objectives and assessment measures for each competency. The Undergraduate Education Subcommittee (UES) of the American Academy of Neurology (AAN) assembled a group of neuroscience educators to outline a longitudinal competency-based curriculum in medical neuroscience encompassing both preclinical and clinical coursework. In development of this curriculum, the committee reviewed United States Medical Licensing Examination content outlines, Liaison Committee on Medical Education requirements, prior AAN-mandated core curricula for basic neuroscience and clinical neurology, and survey responses from educators in US medical schools. The newly recommended curriculum provides an outline of learning objectives for each of the 6 competencies, listing each learning objective in active terms. Documentation of experiences is emphasized, and assessment measures are suggested to demonstrate adequate achievement in each competency. These guidelines, widely vetted and approved by the UES membership, aspire to be both useful as a stand-alone curriculum and also provide a framework for neuroscience educators who wish to develop a more detailed focus in certain areas of study.

  6. Wavelet-Based Adaptive Solvers on Multi-core Architectures for the Simulation of Complex Systems

    NASA Astrophysics Data System (ADS)

    Rossinelli, Diego; Bergdorf, Michael; Hejazialhosseini, Babak; Koumoutsakos, Petros

    We build wavelet-based adaptive numerical methods for the simulation of advection dominated flows that develop multiple spatial scales, with an emphasis on fluid mechanics problems. Wavelet based adaptivity is inherently sequential and in this work we demonstrate that these numerical methods can be implemented in software that is capable of harnessing the capabilities of multi-core architectures while maintaining their computational efficiency. Recent designs in frameworks for multi-core software development allow us to rethink parallelism as task-based, where parallel tasks are specified and automatically mapped into physical threads. This way of exposing parallelism enables the parallelization of algorithms that were considered inherently sequential, such as wavelet-based adaptive simulations. In this paper we present a framework that combines wavelet-based adaptivity with the task-based parallelism. We demonstrate good scaling performance obtained by simulating diverse physical systems on different multi-core and SMP architectures using up to 16 cores.

  7. A surface systems architecture for an evolutionary lunar base

    NASA Technical Reports Server (NTRS)

    Roberts, Barney B.; Pieniazek, Lester A.

    1990-01-01

    The NASA Office of Exploration has completed a Systems Engineering and Integration effort to define a point design for an evolving lunar base that supports substantial science, exploration, and resource production objectives. This study addressed systems level design; element requirements and conceptual designs; assessments of precursor and technology needs, and operations concepts. The central base is assumed to be located equatorially on the lunar nearside north of the crater Moltke in Mare Tranquillitatis. The study considers an aggressive case with three main phases. The initial Man-Tended Phase establishes basic enabling facilities that include a modular habitat that periodically houses a crew of four. During the Experimental Phase the base becomes permanently manned with the construction of a larger habitat that provides augmented workshop and laboratory volumes and housing for crew. The Operational Phase expands base capabilities to a substantially mature level while reducing reliance on earth.

  8. A federated schema-based middleware architecture for hospital information systems.

    PubMed

    Hasselbring, W

    1997-01-01

    An important concern in distributed hospital information systems is the integration of information across heterogeneous subsystems. Consistent data replication is a central problem to be solved in this domain. The specific requirements and problems for integration of information within hospitals are discussed and a middleware architecture which has been designed according to these requirements is presented. Communication servers are often deployed in hospitals to connect heterogeneous subsystems. This paper discusses some problems with this approach and presents a federated schema-based middleware architecture as an alternative solution for propagation of information updates across heterogeneous subsystems within hospitals.

  9. Architectural, Mechanical, Electrical, Plumbing, and Site Documents Associated with Sustainability Base, N232

    NASA Technical Reports Server (NTRS)

    Grymes, Rosalind A.; Martin, Rodney Alexander; Dianati, Soheila

    2016-01-01

    These files contain more precise and accurate representations of the architectural, mechanical, electrical, plumbing, and site information pertaining to Sustainability Base, aka Collaborative Support Facility, aka N232. These supersede the 'bid' drawings released in STI 8112 previously. They are useful for NASA researchers and collaborators in modeling the performance characteristics of the facility. Otherwise, they do not contain new data.

  10. Distributed computing architecture for image-based wavefront sensing and 2D FFTs

    NASA Astrophysics Data System (ADS)

    Smith, Jeffrey S.; Dean, Bruce H.; Haghani, Shadan

    2006-06-01

    Image-based wavefront sensing provides significant advantages over interferometric-based wavefront sensors such as optical design simplicity and stability. However, the image-based approach is computationally intensive, and therefore, applications utilizing the image-based approach gain substantial benefits using specialized high-performance computing architectures. The development and testing of these computing architectures are essential to missions such as James Webb Space Telescope (JWST), Terrestrial Planet Finder-Coronagraph (TPF-C and CorSpec), and the Spherical Primary Optical Telescope (SPOT). The algorithms implemented on these specialized computing architectures make use of numerous two-dimensional Fast Fourier Transforms (FFTs) which necessitate an all-to-all communication when applied on a distributed computational architecture. Several solutions for distributed computing are presented with an emphasis on a 64 Node cluster of digital signal processors (DSPs) and multiple DSP field programmable gate arrays (FPGAs), offering a novel application of low-diameter graph theory. Timing results and performance analysis are presented. The solutions offered could be applied to other computationally complex all-to-all communication problems.

  11. ESPA-Based Multiple Satellite Architecture for Mars Science and Exploration

    NASA Astrophysics Data System (ADS)

    Lo, A. S.; Griffin, K.; Hanson, M.; Lee, G.

    2012-06-01

    We propose a LCROSS-based approach, enabled by ts innovative use of the ESPA ring. Exploiting this architecture for Mars mission can use the upcoming Mars launch opportunities to inject multiple satellites that can support the wide range of NASA’s goals.

  12. Compiling for Novel Scratch Pad Memory based Multicore Architectures for Extreme Scale Computing

    SciTech Connect

    Shrivastava, Aviral

    2016-02-05

    The objective of this proposal is to develop tools and techniques (in the compiler) to manage data of a task and communication among tasks on the scratch pad memory (SPM) of the core, so that any application (a set of tasks) can be executed efficiently on an SPM based manycore architecture.

  13. Distributed Computing Architecture for Image-Based Wavefront Sensing and 2 D FFTs

    NASA Technical Reports Server (NTRS)

    Smith, Jeffrey S.; Dean, Bruce H.; Haghani, Shadan

    2006-01-01

    Image-based wavefront sensing (WFS) provides significant advantages over interferometric-based wavefi-ont sensors such as optical design simplicity and stability. However, the image-based approach is computational intensive, and therefore, specialized high-performance computing architectures are required in applications utilizing the image-based approach. The development and testing of these high-performance computing architectures are essential to such missions as James Webb Space Telescope (JWST), Terrestial Planet Finder-Coronagraph (TPF-C and CorSpec), and Spherical Primary Optical Telescope (SPOT). The development of these specialized computing architectures require numerous two-dimensional Fourier Transforms, which necessitate an all-to-all communication when applied on a distributed computational architecture. Several solutions for distributed computing are presented with an emphasis on a 64 Node cluster of DSPs, multiple DSP FPGAs, and an application of low-diameter graph theory. Timing results and performance analysis will be presented. The solutions offered could be applied to other all-to-all communication and scientifically computationally complex problems.

  14. An Autonomous Mobile Agent-Based Distributed Learning Architecture: A Proposal and Analytical Analysis

    ERIC Educational Resources Information Center

    Ahmed, Iftikhar; Sadeq, Muhammad Jafar

    2006-01-01

    Current distance learning systems are increasingly packing highly data-intensive contents on servers, resulting in the congestion of network and server resources at peak service times. A distributed learning system based on faded information field (FIF) architecture that employs mobile agents (MAs) has been proposed and simulated in this work. The…

  15. Architecture, Design, and Development of an HTML/JavaScript Web-Based Group Support System.

    ERIC Educational Resources Information Center

    Romano, Nicholas C., Jr.; Nunamaker, Jay F., Jr.; Briggs, Robert O.; Vogel, Douglas R.

    1998-01-01

    Examines the need for virtual workspaces and describes the architecture, design, and development of GroupSystems for the World Wide Web (GSWeb), an HTML/JavaScript Web-based Group Support System (GSS). GSWeb, an application interface similar to a Graphical User Interface (GUI), is currently used by teams around the world and relies on user…

  16. Exploration Space Suit Architecture and Destination Environmental-Based Technology Development

    NASA Technical Reports Server (NTRS)

    Hill, Terry R.; McFarland, Shane M.; Korona, F. Adam

    2013-01-01

    This paper continues forward where EVA Space Suit Architecture: Low Earth Orbit Vs. Moon Vs. Mars left off in the development of a space suit architecture that is modular in design and could be reconfigured prior to launch or during any given mission depending on the tasks or destination. This space suit system architecture and technologies required based on human exploration (EVA) destinations will be discussed, and how these systems should evolve to meet the future exploration EVA needs of the US human space flight program. A series of exercises and analyses provided a strong indication that the Constellation Program space suit architecture, with its maximum reuse of technology and functionality across a range of mission profiles and destinations, is postured to provide a viable solution for future space exploration missions. The destination environmental analysis demonstrates that the modular architecture approach could provide the lowest mass and mission cost for the protection of the crew, given any human mission outside of low-Earth orbit. Additionally, some of the high-level trades presented here provide a review of the environmental and nonenvironmental design drivers that will become increasingly important as humans venture farther from Earth. The presentation of destination environmental data demonstrates a logical clustering of destination design environments that allows a focused approach to technology prioritization, development, and design that will maximize the return on investment, largely independent of any particular design reference mission.

  17. Exploration Space Suit Architecture and Destination Environmental-Based Technology Development

    NASA Technical Reports Server (NTRS)

    Hill, Terry R.; McFarland, Shane M.; Korona, F. Adam

    2013-01-01

    This paper continues forward where EVA Space Suit Architecture: Low Earth Orbit Vs. Moon Vs. Mars1 left off in the development of a space suit architecture that is modular in design and could be reconfigured prior to launch or during any given mission depending on the tasks or destination. This paper addresses the space suit system architecture and technologies required based on human exploration (EVA) destinations, and describes how these systems should evolve to meet the future exploration EVA needs of the US human space flight program. A series of exercises and analyses provided a strong indication that the Constellation Program space suit architecture, with its maximum reuse of technology and functionality across a range of mission profiles and destinations, is postured to provide a viable solution for future space exploration missions. The destination environmental analysis demonstrates that the modular architecture approach could provide the lowest mass and mission cost for the protection of the crew, given any human mission outside of low-Earth orbit. Additionally, some of the high-level trades presented here provide a review of the environmental and non-environmental design drivers that will become increasingly important as humans venture farther from Earth. This paper demonstrates a logical clustering of destination design environments that allows a focused approach to technology prioritization, development, and design that will maximize the return on investment, largely independent of any particular design reference mission.

  18. A subsumptive, hierarchical, and distributed vision-based architecture for smart robotics.

    PubMed

    DeSouza, Guilherme N; Kak, Avinash C

    2004-10-01

    We present a distributed vision-based architecture for smart robotics that is composed of multiple control loops, each with a specialized level of competence. Our architecture is subsumptive and hierarchical, in the sense that each control loop can add to the competence level of the loops below, and in the sense that the loops can present a coarse-to-fine gradation with respect to vision sensing. At the coarsest level, the processing of sensory information enables a robot to become aware of the approximate location of an object in its field of view. On the other hand, at the finest end, the processing of stereo information enables a robot to determine more precisely the position and orientation of an object in the coordinate frame of the robot. The processing in each module of the control loops is completely independent and it can be performed at its own rate. A control Arbitrator ranks the results of each loop according to certain confidence indices, which are derived solely from the sensory information. This architecture has clear advantages regarding overall performance of the system, which is not affected by the "slowest link," and regarding fault tolerance, since faults in one module does not affect the other modules. At this time we are able to demonstrate the utility of the architecture for stereoscopic visual servoing. The architecture has also been applied to mobile robot navigation and can easily be extended to tasks such as "assembly-on-the-fly."

  19. Novel ring-based architecture for TWDM-PON with high reliability and flexible extensibility

    NASA Astrophysics Data System (ADS)

    Xiong, Yu; Sun, Peng; Li, Zhiqiang

    2017-02-01

    Time and wavelength division multiplexed passive optical network (TWDM-PON) was determined as a primary solution to NG-PON2 by the full service access network (FSAN) in 2012. Since then, TWDM-PON has been applied to a wider set of applications, including those that are outage sensitive and expansion flexible. So the protection techniques with reliability and flexibility should be studied to address the above needs. In this paper, we propose a novel ring-based architecture for TWDM-PON. The architecture can provide reliable ring protection scheme against a fiber fault occurring on main ring (MR), sub-ring (SR) or last mile ring (LMR). In addition, we exploit the extended node (EN) to realize the network expansion conveniently and smoothly for the flexible extensibility. Thus, more remote nodes(RNs) and optical network units (ONUs) could access this architecture through EN. Moreover, in order to further improve reliability of the network, we design the 1:1 protection scheme against the connected fiber fault between RN and EN. The results show that the proposed architecture has a recovery time of 17 ms under protection mode and the reliability of the network is also illustrated to be greatly improved compared to the network without protection. As the number of ONUs increases, the average cost of each ONU could be gradually reduced. Finally, the simulations verify the feasibility of the architecture.

  20. Empirical mode decomposition of digital mammograms for the statistical based characterization of architectural distortion.

    PubMed

    Zyout, Imad; Togneri, Roberto

    2015-01-01

    Among the different and common mammographic signs of the early-stage breast cancer, the architectural distortion is the most difficult to be identified. In this paper, we propose a new multiscale statistical texture analysis to characterize the presence of architectural distortion by distinguishing between textural patterns of architectural distortion and normal breast parenchyma. The proposed approach, firstly, applies the bidimensional empirical mode decomposition algorithm to decompose each mammographic region of interest into a set of adaptive and data-driven two-dimensional intrinsic mode functions (IMF) layers that capture details or high-frequency oscillations of the input image. Then, a model-based approach is applied to IMF histograms to acquire the first order statistics. The normalized entropy measure is also computed from each IMF and used as a complementary textural feature for the recognition of architectural distortion patterns. For evaluating the proposed AD characterization approach, we used a mammographic dataset of 187 true positive regions (i.e. depicting architectural distortion) and 887 true negative (normal parenchyma) regions, extracted from the DDSM database. Using the proposed multiscale textural features and the nonlinear support vector machine classifier, the best classification performance, in terms of the area under the receiver operating characteristic curve (or Az value), achieved was 0.88.

  1. A hybrid layer-multiplexing and pipeline architecture for efficient FPGA-based multilayer neural network

    NASA Astrophysics Data System (ADS)

    Dong, Yiping; Li, Ce; Lin, Zhen; Watanabe, Takahiro

    This paper presents a novel architecture for an FPGA-based implementation of multilayer Artificial Neural Network (ANN), which integrates both the layer-multiplexing and pipeline architecture. Given a kind of FPGA to be used, the proposed method aims at enhancing the efficiency of resource usage of the FPGA and improving the forward speed at the module level, so that a larger ANN can be implemented on traditional FPGAs and also a high performance is achieved. Usually FPGA board is not changed for every applications, thus, we need not mind about the usage of it if the application can be implemented within the resource limitation. We developed a new mapping method from ANN schematic to FPGA by using this hybrid architecture, and also developed an algorithm to automatically determine the architecture by optimizing the application specific neural network topology. The experimental results show that the proposed architecture can produce a very compact circuit for multilayer ANN to meet resource limitation of a given FPGA. Furthermore, higher performance is obtained as compared with conventional methods.

  2. A real-time CORBA based system architecture for robot assisted craniofacial surgery.

    PubMed

    Pernozzoli, A; Burghart, C; Brief, J; Hassfeld, S; Raczkowsky, J; Mühling, J; Rembold, U; Wörn, H

    2000-01-01

    We present the concept of a system architecture for the computer aided craniofacial surgery. The architecture is based on CORBA, an industrial standard specification for the development of distributed applications. Our concept includes a fundamental behaviour oriented communication model and some fundamental software safety considerations. We've developed a standard library for the integration of new services and devices into our system architecture. It decreases development time noticeably. We tested the performance and usability of our concept on an evaluation set up consisting of a surgery robot system, an infrared navigation system, a force-torque sensor and a visualisation software, obtaining excellent results. Future work will consist in the integration of further devices and the extension of our safety concept. An accurate clinical evaluation will take place continuously.

  3. A common network architecture efficiently implements a variety of sparsity-based inference problems.

    PubMed

    Charles, Adam S; Garrigues, Pierre; Rozell, Christopher J

    2012-12-01

    The sparse coding hypothesis has generated significant interest in the computational and theoretical neuroscience communities, but there remain open questions about the exact quantitative form of the sparsity penalty and the implementation of such a coding rule in neurally plausible architectures. The main contribution of this work is to show that a wide variety of sparsity-based probabilistic inference problems proposed in the signal processing and statistics literatures can be implemented exactly in the common network architecture known as the locally competitive algorithm (LCA). Among the cost functions we examine are approximate l(p) norms (0 ≤ p ≤ 2), modified l(p)-norms, block-l1 norms, and reweighted algorithms. Of particular interest is that we show significantly increased performance in reweighted l1 algorithms by inferring all parameters jointly in a dynamical system rather than using an iterative approach native to digital computational architectures.

  4. Analysis of a Smartphone-Based Architecture with Multiple Mobility Sensors for Fall Detection

    PubMed Central

    Santoyo-Ramón, Jose Antonio; Cano-García, Jose Manuel

    2016-01-01

    During the last years, many research efforts have been devoted to the definition of Fall Detection Systems (FDSs) that benefit from the inherent computing, communication and sensing capabilities of smartphones. However, employing a smartphone as the unique sensor in a FDS application entails several disadvantages as long as an accurate characterization of the patient’s mobility may force to transport this personal device on an unnatural position. This paper presents a smartphone-based architecture for the automatic detection of falls. The system incorporates a set of small sensing motes that can communicate with the smartphone to help in the fall detection decision. The deployed architecture is systematically evaluated in a testbed with experimental users in order to determine the number and positions of the sensors that optimize the effectiveness of the FDS, as well as to assess the most convenient role of the smartphone in the architecture. PMID:27930736

  5. Remote operation of robotics systems using WLAN- and CORBA-based architecture

    NASA Astrophysics Data System (ADS)

    Tikanmaki, Antti; Riekki, Jukka P.; Roning, Juha

    2003-10-01

    Our work describes generic solutions for controlling various different robots through IEEE 802.11b Wireless LAN. Our goals have been to develop a remote-operating architecture for robots with different configurations of sensors and actuators, as well as, controlling multiple robots through a wireless network. Our earlier development work on network-distributed control architecture for mobile robots provides a suitable platform for remote operation. In CORBA based architecture, new sensors or actuators, and new automatic functionality are easy to append. In addition to functionality, we have been developing user interfaces that contain generally useful components for multiple purposes and a possibility to control different shapes of robots and multiple robots at the same time. As a basic idea, the user interface should always be easily customizable, platform portable and require only a minimum amount of installation packages.

  6. Building a logical EHR architecture based on ISO 13606 standard and semantic web technologies.

    PubMed

    Santos, Marcelo R; Bax, Marcello P; Kalra, Dipak

    2010-01-01

    Among the existing patterns of EHR interoperability, the ISO 13606 standard is an important consideration. It is believed that the use of this norm, in conjunction with semantic technologies, may aid in the construction of a robust architecture, keeping in mind the challenges of semantic interoperability. The objective of this paper is to present a proposal for an EHR architecture, based on ISO 13606 and on the utilization of semantic technologies, for a real EHR scenario. In order to accomplish that, a real EHR scenario is described, as well as its main interoperability requirements and a candidate architecture is proposed to solve the presented challenges of interoperability. The ability of the ISO 13606 EHR reference model to accommodate the scenario was highlighted, together with the support provided by the use of the ontology specification languages--RDF and OWL--in respect to the maintenance of a controlled vocabulary.

  7. The Design of a Fault-Tolerant COTS-Based Bus Architecture for Space Applications

    NASA Technical Reports Server (NTRS)

    Chau, Savio N.; Alkalai, Leon; Tai, Ann T.

    2000-01-01

    The high-performance, scalability and miniaturization requirements together with the power, mass and cost constraints mandate the use of commercial-off-the-shelf (COTS) components and standards in the X2000 avionics system architecture for deep-space missions. In this paper, we report our experiences and findings on the design of an IEEE 1394 compliant fault-tolerant COTS-based bus architecture. While the COTS standard IEEE 1394 adequately supports power management, high performance and scalability, its topological criteria impose restrictions on fault tolerance realization. To circumvent the difficulties, we derive a "stack-tree" topology that not only complies with the IEEE 1394 standard but also facilitates fault tolerance realization in a spaceborne system with limited dedicated resource redundancies. Moreover, by exploiting pertinent standard features of the 1394 interface which are not purposely designed for fault tolerance, we devise a comprehensive set of fault detection mechanisms to support the fault-tolerant bus architecture.

  8. Medical library service in a community-based medical school: a case study in South Dakota.

    PubMed Central

    Brennen, P W; Boilard, D W

    1981-01-01

    The historical background of community-based medical schools is described with emphasis on the experiences of the University of South Dakota Lommen Health Sciences Library. The steps undertaken by the library to meet Liaison Committee for Medical Education accreditation standards required for a full four-year, M.D.-degree granting institution are outlined. The governance structure of the participating Libraries of the Affiliated Teaching Hospitals Council is described. Special problems and their solutions are discussed in the context of providing service to a medical school which is decentralized on a statewide basis. PMID:7470677

  9. Medical library service in a community-based medical school: a case study in South Dakota.

    PubMed

    Brennen, P W; Boilard, D W

    1981-01-01

    The historical background of community-based medical schools is described with emphasis on the experiences of the University of South Dakota Lommen Health Sciences Library. The steps undertaken by the library to meet Liaison Committee for Medical Education accreditation standards required for a full four-year, M.D.-degree granting institution are outlined. The governance structure of the participating Libraries of the Affiliated Teaching Hospitals Council is described. Special problems and their solutions are discussed in the context of providing service to a medical school which is decentralized on a statewide basis.

  10. High-speed VMEbus-based analog neurocomputing architecture for image classification

    NASA Astrophysics Data System (ADS)

    Tran, Mua D.; Duong, Tuan A.; Tawel, Raoul; Daud, Taher; Thakoor, Anilkumar P.

    1995-04-01

    To fully exploit the real-time computational capabilities of neural networks (NN) -- as applied to image processing applications -- a high performance VMEbus based analog neurocomputing architecture (VMENA) is developed. The inherent parallelism of an analog VLSI NN embodiment enables a fully parallel and hence high speed and high-throughput hardware implementation of NN architectures. The VMEbus interface is specifically chosen to overcome the limited bandwidth of the PC host computer industrial standard architecture (ISA) bus. The NN board is built around cascadable VLSI NN chips (32 X 32 synapse chips and 32 X 32 neuron/synapse composite chips) for a total of 64 neurons and over 8 K synapses. Under software control, the system architecture could be flexibly reconfigured from feedback to feedforward and vice versa, and once selected, the NN topology (i.e. the number of neurons per input, hidden, and output layer and the number of layers) could be carved out from the set of neuron and synapse resources. An efficient hardware-in-the-loop cascade backpropagation (CBP) learning algorithm is implemented on the hardware. This supervised learning algorithm allows the network architecture to dynamically evolve by adding hidden neurons while modulating their synaptic weights using standard gradient-descent backpropagation. As a demonstration, the NN hardware system is applied to a computationally intensive map-data classification problem. Training sets ranging in size from 50 to 2500 pixels are utilized to train the network, and the best result for the hardware-in-the-loop learning is found to be comparable to the best result of the software NN simulation. Once trained, the VMENA subsystem is capable of processing at approximately 75,000 feedforward passes/second, resulting in over twofold computational throughput improvement relative to the ISAbus based neural network architecture.

  11. Hybrid architecture for encoded measurement-based quantum computation

    PubMed Central

    Zwerger, M.; Briegel, H. J.; Dür, W.

    2014-01-01

    We present a hybrid scheme for quantum computation that combines the modular structure of elementary building blocks used in the circuit model with the advantages of a measurement-based approach to quantum computation. We show how to construct optimal resource states of minimal size to implement elementary building blocks for encoded quantum computation in a measurement-based way, including states for error correction and encoded gates. The performance of the scheme is determined by the quality of the resource states, where within the considered error model a threshold of the order of 10% local noise per particle for fault-tolerant quantum computation and quantum communication. PMID:24946906

  12. [Evidence-based management of medical disposable materials].

    PubMed

    Yang, Hai

    2009-03-01

    Evidence-based management of medical disposable materials pays attention to collect evidence comprehensively and systematically, accumulate and create evidence through its own work and also evaluate evidence strictly. This can be used as a function to guide out job. Medical disposable materials evidence system contains product register qualification, product quality certification, supplier's behavior, internal and external communication evidence. Managers can find different ways in creating and using evidence referring to specific inside and outside condition. Evidence-based management can help accelerating the development of management of medical disposable materials from traditional experience pattern to a systematic and scientific pattern. It also has the very important meaning to improve medical quality, control the unreasonable growth of medical expense and make purchase and supply chain be more efficient.

  13. Exploration Space Suit Architecture and Destination Environmental-Based Technology Development

    NASA Technical Reports Server (NTRS)

    Hill, Terry R.; Korona, F. Adam; McFarland, Shane

    2012-01-01

    This paper continues forward where EVA Space Suit Architecture: Low Earth Orbit Vs. Moon Vs. Mars [1] left off in the development of a space suit architecture that is modular in design and could be reconfigured prior to launch or during any given mission depending on the tasks or destination. This paper will address the space suit system architecture and technologies required based upon human exploration extravehicular activity (EVA) destinations, and describe how they should evolve to meet the future exploration EVA needs of the US human space flight program.1, 2, 3 In looking forward to future US space exploration to a space suit architecture with maximum reuse of technology and functionality across a range of mission profiles and destinations, a series of exercises and analyses have provided a strong indication that the Constellation Program (CxP) space suit architecture is postured to provide a viable solution for future exploration missions4. The destination environmental analysis presented in this paper demonstrates that the modular architecture approach could provide the lowest mass and mission cost for the protection of the crew given any human mission outside of low-Earth orbit (LEO). Additionally, some of the high-level trades presented here provide a review of the environmental and non-environmental design drivers that will become increasingly important the farther away from Earth humans venture. This paper demonstrates a logical clustering of destination design environments that allows a focused approach to technology prioritization, development, and design that will maximize the return on investment, independent of any particular program, and provide architecture and design solutions for space suit systems in time or ahead of need dates for any particular crewed flight program in the future. The approach to space suit design and interface definition discussion will show how the architecture is very adaptable to programmatic and funding changes with

  14. Agent-based modeling supporting the migration of registry systems to grid based architectures.

    PubMed

    Cryer, Martin E; Frey, Lewis

    2009-03-01

    With the increasing age and cost of operation of the existing NCI SEER platform core technologies, such essential resources in the fight against cancer as these will eventually have to be migrated to Grid based systems. In order to model this migration, a simulation is proposed based upon an agent modeling technology. This modeling technique allows for simulation of complex and distributed services provided by a large scale Grid computing platform such as the caBIG(™) project's caGRID. In order to investigate such a migration to a Grid based platform technology, this paper proposes using agent-based modeling simulations to predict the performance of current and Grid configurations of the NCI SEER system integrated with the existing translational opportunities afforded by caGRID. The model illustrates how the use of Grid technology can potentially improve system response time as systems under test are scaled. In modeling SEER nodes accessing multiple registry silos, we show that the performance of SEER applications re-implemented in a Grid native manner exhibits a nearly constant user response time with increasing numbers of distributed registry silos, compared with the current application architecture which exhibits a linear increase in response time for increasing numbers of silos.

  15. Product Lifecycle Management Architecture: A Model Based Systems Engineering Analysis.

    SciTech Connect

    Noonan, Nicholas James

    2015-07-01

    This report is an analysis of the Product Lifecycle Management (PLM) program. The analysis is centered on a need statement generated by a Nuclear Weapons (NW) customer. The need statement captured in this report creates an opportunity for the PLM to provide a robust service as a solution. Lifecycles for both the NW and PLM are analyzed using Model Based System Engineering (MBSE).

  16. Power and area-optimised Carry-Select Adder architecture for standard cell-based design

    NASA Astrophysics Data System (ADS)

    Shanmugam, Muthukumar; Choi, GoangSeog

    2015-08-01

    A Carry-Select Adder (CSA) is one of the most suitable adders for high-speed applications, but the power and area penalties are greater, because it requires a double Ripple-Carry Adder (RCA) structure corresponding to carry inputs 0 and 1. Current low-power and low-area techniques are not suitable for a standard cell-based design which is one of the widely adopted design methodologies. Our work proposes two simple optimised architectures suitable for standard cell-based designs. A simple decision logic that replaces the RCA for Carry input 1 in a conventional CSA is proposed. One of the proposed architectures reduces power and area significantly with a small delay penalty compared to the existing techniques. Another proposed architecture improves the speed of operation and reduces the power and area considerably. The first one is more suitable for high-speed arithmetic in battery-operated applications where there is a trade-off between speed and power, while the other one is suitable for high-performance applications which also require area and power optimisation. The proposed architectures were implemented in TSMC 0.18um CMOS technology, and compared with conventional Square Root Carry-Select Adders and an existing standard cell-based design.

  17. Building a prototype of a Martian base in Poland, an architectural design overview and progress report

    NASA Astrophysics Data System (ADS)

    Kozicki, Janek

    This talk focuses on recent advances in the construction of a prototype 1000 m2 Martian out-post for 8 inhabitants. The architectural design for such a Martian base has been presented previously on COSPAR 2008, the presentation being entitled ,,Architectural design proposal for a Martian base to continue NASA Mars Design Reference Mission". The presentation was welcomed with warm interest by various institutions, some of which offered help in building a prototype such as providing the building site or funding. This year's oral presentation will focus on a progress report and will briefly describe the architectural design. The architectural design is inspired by terrestrial pneumatic architecture. It has small volume, can be easily transported and provides a large habitable space. An architectural solution analo-gous to a terrestrial house with a studio and a workshop was assumed. The spatial placement of the following zones was carefully considered: residential, agricultural and science, as well as garage and workshop. Further attention was paid to transportation routes and a control and communications center. The issues of a life support system, energy, food, water and waste recycling were also discussed. This Martian base was designed to be crewed by a team of eight people to stay on Mars for at least one and a half year. An Open Plan architectural solution was assumed, with a high level of modularity. Walls of standardized sizes with zip-fasteners allow free rearrangement of the interior to adapt to a new situation. The prototype of such a Polish-origin Martian outpost will be used in a manner similar to MDRS or FMARS but to a larger extent. The prototype's design itself will be tested and corrected to achieve a design which can be used on Mars. The procedure of unfolding the pneumatic modules and floor leveling will be tested. The 1000 m2 interior will be used for various simulation exercises: socio-psychological testing, interior arrangement experiments

  18. The design of a CORBA-based PACS in three-tier architecture

    NASA Astrophysics Data System (ADS)

    Li, Zhuo; Wu, Lingda; Wei, Yingmei; Xie, Hongwei

    2005-04-01

    In the past the most of the traditional PACS adopt two-tier Client/Server architecture based on DICOM network in china. However, with the developments of PACS that becomes more large-scale and distributed, the traditional PACS architecture has a lot of weaknesses. To overcome these shortcomings, this paper presents a CORBA-based PACS in three-tier architecture which consists of the application-tier, the middle-tier and the DICOM data-tier. In application-tier, the upper applications can use the service offered from the middle-tier through the application interface. In middle-tier, the characteristic service of PACS, which are extracted from the traditional PACS, are wrapped in service components plug in the ORB software bus. For the data exchange in CORBA-based implementation, the middleware uses IIOP to call service components through the ORB then to return the results to the application-tier. The CORBA object services are responsible for the object location, creation, implementation and destruction, etc. In DICOM data-tier, DICOM image modalities and DICOM databases provide DICOM data for the middle-tier through DICOM image access service. Furthermore, a design of DICOM image access service, which accesses DICOM data and shields the middle-tier from the complexities of DICOM data structure and DIMSE protocol, is presented in this paper. After referred to the CIAS (Clinical Image Access Service) specification defined by OMG, a simplified IDL interface of DICOM image access service is also described. The CORBA-based PACS architecture is an open architecture allowing for the scalability and the interconnectivity & interoperability.

  19. Medication Safety During Pregnancy: Improving Evidence-Based Practice.

    PubMed

    Sinclair, Susan M; Miller, Richard K; Chambers, Christina; Cooper, Elizabeth M

    2016-01-01

    Nearly 90% of women in the United States have taken medications during pregnancy. Medication exposures during pregnancy can result in adverse pregnancy and neonatal outcomes including birth defects, fetal loss, intrauterine growth restriction, prematurity, and longer-term neurodevelopmental outcomes. Advising pregnant women about the safety of medication use during pregnancy is complicated by a lack of data necessary to engage the woman in an informed discussion. Routinely, health care providers turn to the package insert, yet this information can be incomplete and can be based entirely on animal studies. Often, adequate safety data are not available. In a busy clinical setting, health care providers need to be able to quickly locate the most up-to-date information in order to counsel pregnant women concerned about medication exposure. Deciding where to locate the best available information is difficult, particularly when the needed information does not exist. Pregnancy registries are initiated to obtain more data about the safety of specific medication exposures during pregnancy; however, these studies are slow to produce meaningful information, and when they do, the information may not be readily available in a published form. Health care providers have valuable data in their everyday practice that can expand the knowledge base about medication safety during pregnancy. This review aims to discuss the limitations of the package insert regarding medication safety during pregnancy, highlight additional resources available to health care providers to inform practice, and communicate the importance of pregnancy registries for expanding knowledge about medication safety during pregnancy.

  20. A survey of GPU-based medical image computing techniques.

    PubMed

    Shi, Lin; Liu, Wen; Zhang, Heye; Xie, Yongming; Wang, Defeng

    2012-09-01

    Medical imaging currently plays a crucial role throughout the entire clinical applications from medical scientific research to diagnostics and treatment planning. However, medical imaging procedures are often computationally demanding due to the large three-dimensional (3D) medical datasets to process in practical clinical applications. With the rapidly enhancing performances of graphics processors, improved programming support, and excellent price-to-performance ratio, the graphics processing unit (GPU) has emerged as a competitive parallel computing platform for computationally expensive and demanding tasks in a wide range of medical image applications. The major purpose of this survey is to provide a comprehensive reference source for the starters or researchers involved in GPU-based medical image processing. Within this survey, the continuous advancement of GPU computing is reviewed and the existing traditional applications in three areas of medical image processing, namely, segmentation, registration and visualization, are surveyed. The potential advantages and associated challenges of current GPU-based medical imaging are also discussed to inspire future applications in medicine.

  1. Reagent-based, modular, tandem Michael approach for obtaining different indoline alkaloid-inspired polycyclic architectures.

    PubMed

    Brochu, Jean-Louis; Prakesch, Michael; Enright, Gary D; Leek, Donald M; Arya, Prabhat

    2008-01-01

    A modular, reagent-based approach to obtain different indoline alkaloid-inspired, tetracyclic architectures is developed. With the use of TBSOTf as a Lewis acid, we report here a tandem Michael-based approach that led to the synthesis of a diastereomeric mixture of tetracyclic derivatives with two additional six-membered rings. By simply changing the Lewis acid to TMSOTf, we were able to obtain a different tetracyclic compound having additional functionalized 5- and 7-membered rings with complete stereocontrol.

  2. The Architecture of Information Fusion System Ingreenhouse Wireless Sensor Network Based on Multi-Agent

    NASA Astrophysics Data System (ADS)

    Zhu, Wenting; Chen, Ming

    In view of current unprogressive situation of factory breeding in aquaculture, this article designed a standardized, informationized and intelligentized aquaculture system, proposed a information fusion architecture based on multi-agent in greenhouse wireless sensor network (GWSN), and researched mainly the structural characteristic of the four-classed information fusion based on distributed multi-agent and the method to construct the structure inside of every agent.

  3. One-dimension-based spatially ordered architectures for solar energy conversion.

    PubMed

    Liu, Siqi; Tang, Zi-Rong; Sun, Yugang; Colmenares, Juan Carlos; Xu, Yi-Jun

    2015-08-07

    The severe consequences of fossil fuel consumption have resulted in a need for alternative sustainable sources of energy. Conversion and storage of solar energy via a renewable method, such as photocatalysis, holds great promise as such an alternative. One-dimensional (1D) nanostructures have gained attention in solar energy conversion because they have a long axis to absorb incident sunlight yet a short radial distance for separation of photogenerated charge carriers. In particular, well-ordered spatially high dimensional architectures based on 1D nanostructures with well-defined facets or anisotropic shapes offer an exciting opportunity for bridging the gap between 1D nanostructures and the micro and macro world, providing a platform for integration of nanostructures on a larger and more manageable scale into high-performance solar energy conversion applications. In this review, we focus on the progress of photocatalytic solar energy conversion over controlled one-dimension-based spatially ordered architecture hybrids. Assembly and classification of these novel architectures are summarized, and we discuss the opportunity and future direction of integration of 1D materials into high-dimensional, spatially organized architectures, with a perspective toward improved collective performance in various artificial photoredox applications.

  4. RRAM-based parallel computing architecture using k-nearest neighbor classification for pattern recognition

    PubMed Central

    Jiang, Yuning; Kang, Jinfeng; Wang, Xinan

    2017-01-01

    Resistive switching memory (RRAM) is considered as one of the most promising devices for parallel computing solutions that may overcome the von Neumann bottleneck of today’s electronic systems. However, the existing RRAM-based parallel computing architectures suffer from practical problems such as device variations and extra computing circuits. In this work, we propose a novel parallel computing architecture for pattern recognition by implementing k-nearest neighbor classification on metal-oxide RRAM crossbar arrays. Metal-oxide RRAM with gradual RESET behaviors is chosen as both the storage and computing components. The proposed architecture is tested by the MNIST database. High speed (~100 ns per example) and high recognition accuracy (97.05%) are obtained. The influence of several non-ideal device properties is also discussed, and it turns out that the proposed architecture shows great tolerance to device variations. This work paves a new way to achieve RRAM-based parallel computing hardware systems with high performance. PMID:28338069

  5. The Setting is the Service: How the Architecture of Sober Living Residences Supports Community Based Recovery.

    PubMed

    Wittman, Fried; Jee, Babette; Polcin, Douglas L; Henderson, Diane

    2014-07-01

    The architecture of residential recovery settings is an important silent partner in the alcohol/drug recovery field. The settings significantly support or hinder recovery experiences of residents, and shape community reactions to the presence of sober living houses (SLH) in ordinary neighborhoods. Grounded in the principles of Alcoholics Anonymous, the SLH provides residents with settings designed to support peer based recovery; further, these settings operate in a community context that insists on sobriety and strongly encourages attendance at 12-step meetings. Little formal research has been conducted to show how architectural features of the recovery setting - building appearance, spatial layouts, furnishings and finishes, policies for use of the facilities, physical care and maintenance of the property, neighborhood features, aspects of location in the city - function to promote (or retard) recovery, and to build (or detract from) community support. This paper uses a case-study approach to analyze the architecture of a community-based residential recovery service that has demonstrated successful recovery outcomes for its residents, is popular in its community, and has achieved state-wide recognition. The Environmental Pattern Language (Alexander, Ishikawa, & Silverstein, 1977) is used to analyze its architecture in a format that can be tested, critiqued, and adapted for use by similar programs in many communities, providing a model for replication and further research.

  6. Addressing fundamental architectural challenges of an activity-based intelligence and advanced analytics (ABIAA) system

    NASA Astrophysics Data System (ADS)

    Yager, Kevin; Albert, Thomas; Brower, Bernard V.; Pellechia, Matthew F.

    2015-06-01

    The domain of Geospatial Intelligence Analysis is rapidly shifting toward a new paradigm of Activity Based Intelligence (ABI) and information-based Tipping and Cueing. General requirements for an advanced ABIAA system present significant challenges in architectural design, computing resources, data volumes, workflow efficiency, data mining and analysis algorithms, and database structures. These sophisticated ABI software systems must include advanced algorithms that automatically flag activities of interest in less time and within larger data volumes than can be processed by human analysts. In doing this, they must also maintain the geospatial accuracy necessary for cross-correlation of multi-intelligence data sources. Historically, serial architectural workflows have been employed in ABIAA system design for tasking, collection, processing, exploitation, and dissemination. These simpler architectures may produce implementations that solve short term requirements; however, they have serious limitations that preclude them from being used effectively in an automated ABIAA system with multiple data sources. This paper discusses modern ABIAA architectural considerations providing an overview of an advanced ABIAA system and comparisons to legacy systems. It concludes with a recommended strategy and incremental approach to the research, development, and construction of a fully automated ABIAA system.

  7. RRAM-based parallel computing architecture using k-nearest neighbor classification for pattern recognition

    NASA Astrophysics Data System (ADS)

    Jiang, Yuning; Kang, Jinfeng; Wang, Xinan

    2017-03-01

    Resistive switching memory (RRAM) is considered as one of the most promising devices for parallel computing solutions that may overcome the von Neumann bottleneck of today’s electronic systems. However, the existing RRAM-based parallel computing architectures suffer from practical problems such as device variations and extra computing circuits. In this work, we propose a novel parallel computing architecture for pattern recognition by implementing k-nearest neighbor classification on metal-oxide RRAM crossbar arrays. Metal-oxide RRAM with gradual RESET behaviors is chosen as both the storage and computing components. The proposed architecture is tested by the MNIST database. High speed (~100 ns per example) and high recognition accuracy (97.05%) are obtained. The influence of several non-ideal device properties is also discussed, and it turns out that the proposed architecture shows great tolerance to device variations. This work paves a new way to achieve RRAM-based parallel computing hardware systems with high performance.

  8. The Setting is the Service: How the Architecture of Sober Living Residences Supports Community Based Recovery

    PubMed Central

    Wittman, Fried; Jee, Babette; Polcin, Douglas L.; Henderson, Diane

    2014-01-01

    The architecture of residential recovery settings is an important silent partner in the alcohol/drug recovery field. The settings significantly support or hinder recovery experiences of residents, and shape community reactions to the presence of sober living houses (SLH) in ordinary neighborhoods. Grounded in the principles of Alcoholics Anonymous, the SLH provides residents with settings designed to support peer based recovery; further, these settings operate in a community context that insists on sobriety and strongly encourages attendance at 12-step meetings. Little formal research has been conducted to show how architectural features of the recovery setting – building appearance, spatial layouts, furnishings and finishes, policies for use of the facilities, physical care and maintenance of the property, neighborhood features, aspects of location in the city – function to promote (or retard) recovery, and to build (or detract from) community support. This paper uses a case-study approach to analyze the architecture of a community-based residential recovery service that has demonstrated successful recovery outcomes for its residents, is popular in its community, and has achieved state-wide recognition. The Environmental Pattern Language (Alexander, Ishikawa, & Silverstein, 1977) is used to analyze its architecture in a format that can be tested, critiqued, and adapted for use by similar programs in many communities, providing a model for replication and further research. PMID:25328377

  9. An Architecture for Intelligent Systems Based on Smart Sensors

    NASA Technical Reports Server (NTRS)

    Schmalzel, John; Figueroa, Fernando; Morris, Jon; Mandayam, Shreekanth; Polikar, Robi

    2004-01-01

    Based on requirements for a next-generation rocket test facility, elements of a prototype Intelligent Rocket Test Facility (IRTF) have been implemented. A key component is distributed smart sensor elements integrated using a knowledgeware environment. One of the specific goals is to imbue sensors with the intelligence needed to perform self diagnosis of health and to participate in a hierarchy of health determination at sensor, process, and system levels. The preliminary results provide the basis for future advanced development and validation using rocket test stand facilities at Stennis Space Center (SSC). We have identified issues important to further development of health-enabled networks, which should be of interest to others working with smart sensors and intelligent health management systems.

  10. Development of a power protection system using an agent based architecture

    SciTech Connect

    Wong, S.K.; Kalam, A.

    1995-12-31

    This paper presents an approach to the development of a system for the design, analysis and assessment of power protection schemes. The system aims to assist the protection experts in automating their work and aids them in diagnosing, planning and remembering. The system could also be used as a teaching or training tool for the inexperienced fresh graduates in the field. Protection for power system can be viewed as a sum of coordinated protective devices located in the various parts of a power system. The design of protection schemes depends on the configuration of the system, the specifications the system must meet and the constraints that must be satisfied. Selecting and setting the appropriate relays and protective devices are no easy tasks and require skill, experience, heuristics and common sense knowledge. This paper presents a generic architecture based on multi agent paradigm and introduces a novel approach in the development of an intelligent system. It uses distributed problem solving technique and integrates different reasoning methodologies such as case based, rule based and explanation based. The architecture of the system is based on an object oriented paradigm and utilizes a multi knowledge representation scheme in a case based framework. Part of the system which has been implemented in an object oriented environment shows a promising and convincing demonstration of the system`s architecture and approach.

  11. From Cases to Projects in Problem-Based Medical Education

    ERIC Educational Resources Information Center

    Stentoft, Diana; Duroux, Meg; Fink, Trine; Emmersen, Jeppe

    2014-01-01

    Problem-based learning (PBL) based on patient cases has become a well-established worldwide educational approach in medical education. Recent studies indicate that case-based PBL when used throughout an entire curriculum may develop into a counter-productive routine for students as well as teachers. Consequently, there is a need to develop PBL…

  12. Architectures for a Space-based Gravitational-Wave Observatory

    NASA Astrophysics Data System (ADS)

    Stebbins, Robin

    2015-04-01

    The European Space Agency (ESA) selected the science theme, the ``Gravitational Universe,'' for the third large mission opportunity, known as L3, under its Cosmic Vision Programme. The planned launch date is 2034. ESA is considering a 20% participation by an international partner, and NASA's Astrophysics Division has begun negotiating a NASA role. We have studied the design consequences of a NASA contribution, evaluated the science benefits and identified the technology requirements for hardware that could be delivered by NASA. The European community proposed a strawman mission concept, called eLISA, having two measurement arms, derived from the well studied LISA (Laser Interferometer Space Antenna) concept. The US community is promoting a mission concept known as SGO Mid (Space-based Gravitational-wave Observatory Mid-sized), a three arm LISA-like concept. If NASA were to partner with ESA, the eLISA concept could be transformed to SGO Mid by the addition of a third arm, thereby augmenting science, reducing risk and reducing non-recurring engineering costs. The characteristics of the mission concepts and the relative science performance of eLISA, SGO Mid and LISA are described.

  13. Fractal-based image texture analysis of trabecular bone architecture.

    PubMed

    Jiang, C; Pitt, R E; Bertram, J E; Aneshansley, D J

    1999-07-01

    Fractal-based image analysis methods are investigated to extract textural features related to the anisotropic structure of trabecular bone from the X-ray images of cubic bone specimens. Three methods are used to quantify image textural features: power spectrum, Minkowski dimension and mean intercept length. The global fractal dimension is used to describe the overall roughness of the image texture. The anisotropic features formed by the trabeculae are characterised by a fabric ellipse, whose orientation and eccentricity reflect the textural anisotropy of the image. Tests of these methods with synthetic images of known fractal dimension show that the Minkowski dimension provides a more accurate and consistent estimation of global fractal dimension. Tests on bone x-ray (eccentricity range 0.25-0.80) images indicate that the Minkowski dimension is more sensitive to the changes in textural orientation. The results suggest that the Minkowski dimension is a better measure for characterising trabecular bone anisotropy in the x-ray images of thick specimens.

  14. Novel photonic bandgap based architectures for quantum computers and networks

    NASA Astrophysics Data System (ADS)

    Guney, Durdu

    All of the approaches for quantum information processing have their own advantages, but unfortunately also their own drawbacks. Ideally, one would merge the most attractive features of those different approaches in a single technology. We envision that large-scale photonic crystal (PC) integrated circuits and fibers could be the basis for robust and compact quantum circuits and processors of the next generation quantum computers and networking devices. Cavity QED, solid-state, and (non)linear optical models for computing, and optical fiber approach for communications are the most promising candidates to be improved through this novel technology. In our work, we consider both digital and analog quantum computing. In the digital domain, we first perform gate-level analysis. To achieve this task, we solve the Jaynes-Cummings Hamiltonian with time-dependent coupling parameters under the dipole and rotating-wave approximations for a 3D PC single-mode cavity with a sufficiently high Q-factor. We then exploit the results to show how to create a maximally entangled state of two atoms and how to implement several quantum logic gates: a dual-rail Hadamard gate, a dual-rail NOT gate, and a SWAP gate. In all of these operations, we synchronize atoms, as opposed to previous studies with PCs. The method has the potential for extension to N-atom entanglement, universal quantum logic operations, and the implementation of other useful, cavity QED-based quantum information processing tasks. In the next part of the digital domain, we study circuit-level implementations. We design and simulate an integrated teleportation and readout circuit on a single PC chip. The readout part of our device can not only be used on its own but can also be integrated with other compatible optical circuits to achieve atomic state detection. Further improvement of the device in terms of compactness and robustness is possible by integrating with sources and detectors in the optical regime. In the analog

  15. Implementing a commercial rule base as a medication order safety net.

    PubMed

    Reichley, Richard M; Seaton, Terry L; Resetar, Ervina; Micek, Scott T; Scott, Karen L; Fraser, Victoria J; Dunagan, W Claiborne; Bailey, Thomas C

    2005-01-01

    A commercial rule base (Cerner Multum) was used to identify medication orders exceeding recommended dosage limits at five hospitals within BJC HealthCare, an integrated health care system. During initial testing, clinical pharmacists determined that there was an excessive number of nuisance and clinically insignificant alerts, with an overall alert rate of 9.2%. A method for customizing the commercial rule base was implemented to increase rule specificity for problematic rules. The system was subsequently deployed at two facilities and achieved alert rates of less than 1%. Pharmacists screened these alerts and contacted ordering physicians in 21% of cases. Physicians made therapeutic changes in response to 38% of alerts presented to them. By applying simple techniques to customize rules, commercial rule bases can be used to rapidly deploy a safety net to screen drug orders for excessive dosages, while preserving the rule architecture for later implementations of more finely tuned clinical decision support.

  16. Software architecture for multi-bed FDK-based reconstruction in X-ray CT scanners.

    PubMed

    Abella, M; Vaquero, J J; Sisniega, A; Pascau, J; Udías, A; García, V; Vidal, I; Desco, M

    2012-08-01

    Most small-animal X-ray computed tomography (CT) scanners are based on cone-beam geometry with a flat-panel detector orbiting in a circular trajectory. Image reconstruction in these systems is usually performed by approximate methods based on the algorithm proposed by Feldkamp et al. (FDK). Besides the implementation of the reconstruction algorithm itself, in order to design a real system it is necessary to take into account numerous issues so as to obtain the best quality images from the acquired data. This work presents a comprehensive, novel software architecture for small-animal CT scanners based on cone-beam geometry with circular scanning trajectory. The proposed architecture covers all the steps from the system calibration to the volume reconstruction and conversion into Hounsfield units. It includes an efficient implementation of an FDK-based reconstruction algorithm that takes advantage of system symmetries and allows for parallel reconstruction using a multiprocessor computer. Strategies for calibration and artifact correction are discussed to justify the strategies adopted. New procedures for multi-bed misalignment, beam-hardening, and Housfield units calibration are proposed. Experiments with phantoms and real data showed the suitability of the proposed software architecture for an X-ray small animal CT based on cone-beam geometry.

  17. Competency-based medical education: theory to practice.

    PubMed

    Frank, Jason R; Snell, Linda S; Cate, Olle Ten; Holmboe, Eric S; Carraccio, Carol; Swing, Susan R; Harris, Peter; Glasgow, Nicholas J; Campbell, Craig; Dath, Deepak; Harden, Ronald M; Iobst, William; Long, Donlin M; Mungroo, Rani; Richardson, Denyse L; Sherbino, Jonathan; Silver, Ivan; Taber, Sarah; Talbot, Martin; Harris, Kenneth A

    2010-01-01

    Although competency-based medical education (CBME) has attracted renewed interest in recent years among educators and policy-makers in the health care professions, there is little agreement on many aspects of this paradigm. We convened a unique partnership - the International CBME Collaborators - to examine conceptual issues and current debates in CBME. We engaged in a multi-stage group process and held a consensus conference with the aim of reviewing the scholarly literature of competency-based medical education, identifying controversies in need of clarification, proposing definitions and concepts that could be useful to educators across many jurisdictions, and exploring future directions for this approach to preparing health professionals. In this paper, we describe the evolution of CBME from the outcomes movement in the 20th century to a renewed approach that, focused on accountability and curricular outcomes and organized around competencies, promotes greater learner-centredness and de-emphasizes time-based curricular design. In this paradigm, competence and related terms are redefined to emphasize their multi-dimensional, dynamic, developmental, and contextual nature. CBME therefore has significant implications for the planning of medical curricula and will have an important impact in reshaping the enterprise of medical education. We elaborate on this emerging CBME approach and its related concepts, and invite medical educators everywhere to enter into further dialogue about the promise and the potential perils of competency-based medical curricula for the 21st century.

  18. An Architecture for Automated Fire Detection Early Warning System Based on Geoprocessing Service Composition

    NASA Astrophysics Data System (ADS)

    Samadzadegan, F.; Saber, M.; Zahmatkesh, H.; Joze Ghazi Khanlou, H.

    2013-09-01

    Rapidly discovering, sharing, integrating and applying geospatial information are key issues in the domain of emergency response and disaster management. Due to the distributed nature of data and processing resources in disaster management, utilizing a Service Oriented Architecture (SOA) to take advantages of workflow of services provides an efficient, flexible and reliable implementations to encounter different hazardous situation. The implementation specification of the Web Processing Service (WPS) has guided geospatial data processing in a Service Oriented Architecture (SOA) platform to become a widely accepted solution for processing remotely sensed data on the web. This paper presents an architecture design based on OGC web services for automated workflow for acquisition, processing remotely sensed data, detecting fire and sending notifications to the authorities. A basic architecture and its building blocks for an automated fire detection early warning system are represented using web-based processing of remote sensing imageries utilizing MODIS data. A composition of WPS processes is proposed as a WPS service to extract fire events from MODIS data. Subsequently, the paper highlights the role of WPS as a middleware interface in the domain of geospatial web service technology that can be used to invoke a large variety of geoprocessing operations and chaining of other web services as an engine of composition. The applicability of proposed architecture by a real world fire event detection and notification use case is evaluated. A GeoPortal client with open-source software was developed to manage data, metadata, processes, and authorities. Investigating feasibility and benefits of proposed framework shows that this framework can be used for wide area of geospatial applications specially disaster management and environmental monitoring.

  19. Sleep Architecture as Correlate and Predictor of Symptoms and Impairment in Inter-episode Bipolar Disorder: Taking on the Challenge of Medication Effects

    PubMed Central

    Eidelman, Polina; Talbot, Lisa S.; Gruber, June; Hairston, Ilana; Harvey, Allison G.

    2010-01-01

    This study was designed to clarify the association between inter-episode bipolar disorder and sleep architecture. Participants completed a baseline symptom and sleep assessment and, 3 months later, an assessment of symptoms and impairment. The effects of psychiatric medications on sleep architecture were also considered. Participants included 22 adults with bipolar I or II (inter-episode) and 22 non-psychiatric controls. The sleep assessment was conducted at the Sleep and Psychological Disorders Laboratory at the University of California, Berkeley. Follow-up assessments 3 months later were conducted over the phone. Results indicate that, at the sleep assessment, bipolar participants exhibited greater REM density than control participants with no other group differences in sleep architecture. Sleep architecture was not correlated with concurrent mood symptoms in either group. In the bipolar group, duration of the first REM period and Slow Wave Sleep (SWS) amount were positively correlated with manic symptoms and impairment at 3 months, while REM density was positively correlated with depressive symptoms and impairment at 3 months. The amount of Stage 2 sleep was negatively correlated with manic symptoms and impairment at 3 months. In contrast, for the control group, REM density was negatively correlated with impairment at 3 months. SWS and Stage 2 sleep were not correlated with symptoms or impairment. Study findings suggest that inter-episode REM sleep, SWS and Stage 2 sleep are correlated with future manic and depressive symptoms and impairment in bipolar disorder. This is consistent with the proposition that sleep architecture may be a mechanism of illness maintenance in bipolar disorder. PMID:20408930

  20. Lunar Outpost Life Support Architecture Study Based on a High-Mobility Exploration Scenario

    NASA Technical Reports Server (NTRS)

    Lange, Kevin E.; Anderson, Molly S.

    2010-01-01

    This paper presents results of a life support architecture study based on a 2009 NASA lunar surface exploration scenario known as Scenario 12. The study focuses on the assembly complete outpost configuration and includes pressurized rovers as part of a distributed outpost architecture in both stand-alone and integrated configurations. A range of life support architectures are examined reflecting different levels of closure and distributed functionality. Monte Carlo simulations are used to assess the sensitivity of results to volatile high-impact mission variables, including the quantity of residual Lander oxygen and hydrogen propellants available for scavenging, the fraction of crew time away from the outpost on excursions, total extravehicular activity hours, and habitat leakage. Surpluses or deficits of water and oxygen are reported for each architecture, along with fixed and 10-year total equivalent system mass estimates relative to a reference case. System robustness is discussed in terms of the probability of no water or oxygen resupply as determined from the Monte Carlo simulations.

  1. Distributed Scheduling Architecture for Multi-Center Time-Based Metering

    NASA Technical Reports Server (NTRS)

    Landry, Steven; Farley, Todd; Foster, John; Green, Steve; Hoang, Ty; Wong, Gregory L.

    2003-01-01

    The Traffic Management Advisor (TMA) is an air traffic control automation system currently in use in seven Air Route Traffic Control Centers (ARTCCs) to enable time based metering to busy airports within their airspace. However, this system is limited to operation within a single ARTCC, within about a 200 nautical mile radius of the airport, and on relatively simple streams of traffic. The need for coordinated metering within a greater (300+ nautical mile) radius of an airport, on streams of traffic with significant branching, and across ARTCC boundaries, has been identified. Early tests revealed that TMA could not simply be scaled up to handle such a problem. Instead, a loosely coupled hierarchy of schedules, in which constraints from downstream schedules are passed upstream, is required. Such an architecture reduces the reliance on distant projections of arrival times, making schedules robust to changes in sequence and to additions of aircraft (such as aircraft departing inside the system s scheduling horizon). This architecture is also scaleable, easily reconfigurable, and can be networked together. As such, it can be adapted for use in any size or configuration of airspace and with any number of airports delivering restrictions. An implementation of this distributed scheduling architecture is currently undergoing testing in the TMA-Multi Center system. This paper describes the architecture and its motivation.

  2. Automated detection method for architectural distortion areas on mammograms based on morphological processing and surface analysis

    NASA Astrophysics Data System (ADS)

    Ichikawa, Tetsuko; Matsubara, Tomoko; Hara, Takeshi; Fujita, Hiroshi; Endo, Tokiko; Iwase, Takuji

    2004-05-01

    As well as mass and microcalcification, architectural distortion is a very important finding for the early detection of breast cancer via mammograms, and such distortions can be classified into three typical types: spiculation, retraction, and distortion. The purpose of this work is to develop an automatic method for detecting areas of architectural distortion with spiculation. The suspect areas are detected by concentration indexes of line-structures extracted by using mean curvature. After that, discrimination analysis of nine features is employed for the classifications of true and false positives. The employed features are the size, the mean pixel value, the mean concentration index, the mean isotropic index, the contrast, and four other features based on the power spectrum. As a result of this work, the accuracy of the classification was 76% and the sensitivity was 80% with 0.9 false positives per image in our database in regard to spiculation. It was concluded that our method was effective in detectiong the area of architectural distortion; however, some architectural distortions were not detected accurately because of the size, the density, or the different appearance of the distorted areas.

  3. Agent-Oriented Privacy-Based Information Brokering Architecture for Healthcare Environments

    PubMed Central

    Masaud-Wahaishi, Abdulmutalib; Ghenniwa, Hamada

    2009-01-01

    Healthcare industry is facing a major reform at all levels—locally, regionally, nationally, and internationally. Healthcare services and systems become very complex and comprise of a vast number of components (software systems, doctors, patients, etc.) that are characterized by shared, distributed and heterogeneous information sources with varieties of clinical and other settings. The challenge now faced with decision making, and management of care is to operate effectively in order to meet the information needs of healthcare personnel. Currently, researchers, developers, and systems engineers are working toward achieving better efficiency and quality of service in various sectors of healthcare, such as hospital management, patient care, and treatment. This paper presents a novel information brokering architecture that supports privacy-based information gathering in healthcare. Architecturally, the brokering is viewed as a layer of services where a brokering service is modeled as an agent with a specific architecture and interaction protocol that are appropriate to serve various requests. Within the context of brokering, we model privacy in terms of the entities ability to hide or reveal information related to its identities, requests, and/or capabilities. A prototype of the proposed architecture has been implemented to support information-gathering capabilities in healthcare environments using FIPA-complaint platform JADE. PMID:19325918

  4. OPWUMP: An Architecture for Online Predicting in WUM-Based Personalization System

    NASA Astrophysics Data System (ADS)

    Jalali, Mehrdad; Mustapha, Norwati; Sulaiman, Md Nasir B.; Mamat, Ali

    The Internet is one of the fastest growing areas of intelligence gathering. During their navigation web users leave many records of their activity. This huge amount of data can be a useful source of knowledge. Sophisticated mining processes are needed for this knowledge to be extracted, understood and used. Web Usage Mining (WUM) systems are specifically designed to carry out this task by analyzing the data representing usage data about a particular Web Site. WUM can model user behavior and, therefore, to forecast their future movements. Online prediction is one web usage mining application. However, the accuracy of the prediction and classification in the current architecture of predicting users' future requests systems can not still satisfy users especially in Huge Web sites. To provide online prediction efficiently, we develop an architecture for online predicting in WUM-based personalization system (OPWUMP).This article advances an architecture of Web usage mining for enhancing accuracy of classification by interaction between classification, evaluation, current user activates and user profile in online phase of this architecture.

  5. Towards computerizing intensive care sedation guidelines: design of a rule-based architecture for automated execution of clinical guidelines

    PubMed Central

    2010-01-01

    Background Computerized ICUs rely on software services to convey the medical condition of their patients as well as assisting the staff in taking treatment decisions. Such services are useful for following clinical guidelines quickly and accurately. However, the development of services is often time-consuming and error-prone. Consequently, many care-related activities are still conducted based on manually constructed guidelines. These are often ambiguous, which leads to unnecessary variations in treatments and costs. The goal of this paper is to present a semi-automatic verification and translation framework capable of turning manually constructed diagrams into ready-to-use programs. This framework combines the strengths of the manual and service-oriented approaches while decreasing their disadvantages. The aim is to close the gap in communication between the IT and the medical domain. This leads to a less time-consuming and error-prone development phase and a shorter clinical evaluation phase. Methods A framework is proposed that semi-automatically translates a clinical guideline, expressed as an XML-based flow chart, into a Drools Rule Flow by employing semantic technologies such as ontologies and SWRL. An overview of the architecture is given and all the technology choices are thoroughly motivated. Finally, it is shown how this framework can be integrated into a service-oriented architecture (SOA). Results The applicability of the Drools Rule language to express clinical guidelines is evaluated by translating an example guideline, namely the sedation protocol used for the anaesthetization of patients, to a Drools Rule Flow and executing and deploying this Rule-based application as a part of a SOA. The results show that the performance of Drools is comparable to other technologies such as Web Services and increases with the number of decision nodes present in the Rule Flow. Most delays are introduced by loading the Rule Flows. Conclusions The framework is an

  6. Product-based Safety Certification for Medical Devices Embedded Software.

    PubMed

    Neto, José Augusto; Figueiredo Damásio, Jemerson; Monthaler, Paul; Morais, Misael

    2015-01-01

    Worldwide medical device embedded software certification practices are currently focused on manufacturing best practices. In Brazil, the national regulatory agency does not hold a local certification process for software-intensive medical devices and admits international certification (e.g. FDA and CE) from local and international industry to operate in the Brazilian health care market. We present here a product-based certification process as a candidate process to support the Brazilian regulatory agency ANVISA in medical device software regulation. Center of Strategic Technology for Healthcare (NUTES) medical device embedded software certification is based on a solid safety quality model and has been tested with reasonable success against the Class I risk device Generic Infusion Pump (GIP).

  7. An improved FCM medical image segmentation algorithm based on MMTD.

    PubMed

    Zhou, Ningning; Yang, Tingting; Zhang, Shaobai

    2014-01-01

    Image segmentation plays an important role in medical image processing. Fuzzy c-means (FCM) is one of the popular clustering algorithms for medical image segmentation. But FCM is highly vulnerable to noise due to not considering the spatial information in image segmentation. This paper introduces medium mathematics system which is employed to process fuzzy information for image segmentation. It establishes the medium similarity measure based on the measure of medium truth degree (MMTD) and uses the correlation of the pixel and its neighbors to define the medium membership function. An improved FCM medical image segmentation algorithm based on MMTD which takes some spatial features into account is proposed in this paper. The experimental results show that the proposed algorithm is more antinoise than the standard FCM, with more certainty and less fuzziness. This will lead to its practicable and effective applications in medical image segmentation.

  8. Two RFID-based solutions to enhance inpatient medication safety.

    PubMed

    Chien, Hung-Yu; Yang, Chia-Chuan; Wu, Tzong-Chen; Lee, Chin-Feng

    2011-06-01

    Owing to the low cost and convenience of identifying an object without physical contact, Radio Frequency Identification (RFID) systems provide innovative, promising and efficient applications in many domains. An RFID grouping protocol is a protocol that allows an off-line verifier to collect and verify the evidence of two or more tags simultaneously present. Recently, Huang and Ku (J. Med. Syst, 2009) proposed an efficient grouping protocol to enhance medication safety for inpatients based on low-cost tags. However, the Huang-Ku scheme is not secure; an attacker can easily make up fake grouping records to cheat the verifier. This weakness would seriously endanger the safety of inpatient medication safety. This paper will show the weaknesses, and then propose two RFID-based solutions to enhance medication safety for two different scenarios. The proposed schemes are practical, secure and efficient for medication applications.

  9. A grid-based model for integration of distributed medical databases.

    PubMed

    Luo, Yongxing; Jiang, Lijun; Zhuang, Tian-ge

    2009-12-01

    Grid has emerged recently as an integration infrastructure for sharing and coordinated use of diverse resources in dynamic, distributed environment. In this paper, we present a prototype system for integration of heterogeneous medical databases based on Grid technology, which can provide a uniform access interface and efficient query mechanism to different medical databases. After presenting the architecture of the prototype system that employs corresponding Grid services and middleware technologies, we make an analysis on its basic functional components including OGSA-DAI, metadata model, transaction management, and query processing in detail, which cooperate with each other to enable uniform accessing and seamless integration of the underlying heterogeneous medical databases. Then, we test effectiveness and performance of the system through a query instance, analyze the experiment result, and make a discussion on some issues relating to practical medical applications. Although the prototype system has been carried out and tested in a simulated hospital information environment at present, the underlying principles are applicable to practical applications.

  10. SpaceWire- Based Control System Architecture for the Lightweight Advanced Robotic Arm Demonstrator [LARAD

    NASA Astrophysics Data System (ADS)

    Rucinski, Marek; Coates, Adam; Montano, Giuseppe; Allouis, Elie; Jameux, David

    2015-09-01

    The Lightweight Advanced Robotic Arm Demonstrator (LARAD) is a state-of-the-art, two-meter long robotic arm for planetary surface exploration currently being developed by a UK consortium led by Airbus Defence and Space Ltd under contract to the UK Space Agency (CREST-2 programme). LARAD has a modular design, which allows for experimentation with different electronics and control software. The control system architecture includes the on-board computer, control software and firmware, and the communication infrastructure (e.g. data links, switches) connecting on-board computer(s), sensors, actuators and the end-effector. The purpose of the control system is to operate the arm according to pre-defined performance requirements, monitoring its behaviour in real-time and performing safing/recovery actions in case of faults. This paper reports on the results of a recent study about the feasibility of the development and integration of a novel control system architecture for LARAD fully based on the SpaceWire protocol. The current control system architecture is based on the combination of two communication protocols, Ethernet and CAN. The new SpaceWire-based control system will allow for improved monitoring and telecommanding performance thanks to higher communication data rate, allowing for the adoption of advanced control schemes, potentially based on multiple vision sensors, and for the handling of sophisticated end-effectors that require fine control, such as science payloads or robotic hands.

  11. Home medical monitoring network based on embedded technology

    NASA Astrophysics Data System (ADS)

    Liu, Guozhong; Deng, Wenyi; Yan, Bixi; Lv, Naiguang

    2006-11-01

    Remote medical monitoring network for long-term monitoring of physiological variables would be helpful for recovery of patients as people are monitored at more comfortable conditions. Furthermore, long-term monitoring would be beneficial to investigate slowly developing deterioration in wellness status of a subject and provide medical treatment as soon as possible. The home monitor runs on an embedded microcomputer Rabbit3000 and interfaces with different medical monitoring module through serial ports. The network based on asymmetric digital subscriber line (ADSL) or local area network (LAN) is established and a client - server model, each embedded home medical monitor is client and the monitoring center is the server, is applied to the system design. The client is able to provide its information to the server when client's request of connection to the server is permitted. The monitoring center focuses on the management of the communications, the acquisition of medical data, and the visualization and analysis of the data, etc. Diagnosing model of sleep apnea syndrome is built basing on ECG, heart rate, respiration wave, blood pressure, oxygen saturation, air temperature of mouth cavity or nasal cavity, so sleep status can be analyzed by physiological data acquired as people in sleep. Remote medical monitoring network based on embedded micro Internetworking technology have advantages of lower price, convenience and feasibility, which have been tested by the prototype.

  12. Automated UMLS-based comparison of medical forms.

    PubMed

    Dugas, Martin; Fritz, Fleur; Krumm, Rainer; Breil, Bernhard

    2013-01-01

    Medical forms are very heterogeneous: on a European scale there are thousands of data items in several hundred different systems. To enable data exchange for clinical care and research purposes there is a need to develop interoperable documentation systems with harmonized forms for data capture. A prerequisite in this harmonization process is comparison of forms. So far--to our knowledge--an automated method for comparison of medical forms is not available. A form contains a list of data items with corresponding medical concepts. An automatic comparison needs data types, item names and especially item with these unique concept codes from medical terminologies. The scope of the proposed method is a comparison of these items by comparing their concept codes (coded in UMLS). Each data item is represented by item name, concept code and value domain. Two items are called identical, if item name, concept code and value domain are the same. Two items are called matching, if only concept code and value domain are the same. Two items are called similar, if their concept codes are the same, but the value domains are different. Based on these definitions an open-source implementation for automated comparison of medical forms in ODM format with UMLS-based semantic annotations was developed. It is available as package compareODM from http://cran.r-project.org. To evaluate this method, it was applied to a set of 7 real medical forms with 285 data items from a large public ODM repository with forms for different medical purposes (research, quality management, routine care). Comparison results were visualized with grid images and dendrograms. Automated comparison of semantically annotated medical forms is feasible. Dendrograms allow a view on clustered similar forms. The approach is scalable for a large set of real medical forms.

  13. Integration of Evidence Based Medicine into a Medical Curriculum

    PubMed Central

    Tamim, H M; Ferwana, M; Al Banyan, E; Al Alwan, I; Hajeer, AH

    2009-01-01

    The College of Medicine at King Saud bin Abdulaziz University for Health Sciences (KSAU-HS) was established in January 2004. The four-year curriculum was based on the Problem Based Learning (PBL) format and involved the web-based graduate medical program adopted from the University of Sydney, Australia. At KSAU-HS, one additional semester was added to the beginning of this curriculum to prepare the students in English language skills, PBL, Information Technology and Evidence Based Medicine (EBM). EBM is part of the Personal and Professional Development (PPD) theme of the medical curriculum and is integrated into each stage of the medical curriculum. These modifications of the University of Sydney curriculum are presented here as a model of EBM integration into a college of medicine curriculum. PMID:20165529

  14. An end-to-end communications architecture for condition-based maintenance applications

    NASA Astrophysics Data System (ADS)

    Kroculick, Joseph

    2014-06-01

    This paper explores challenges in implementing an end-to-end communications architecture for Condition-Based Maintenance Plus (CBM+) data transmission which aligns with the Army's Network Modernization Strategy. The Army's Network Modernization strategy is based on rolling out network capabilities which connect the smallest unit and Soldier level to enterprise systems. CBM+ is a continuous improvement initiative over the life cycle of a weapon system or equipment to improve the reliability and maintenance effectiveness of Department of Defense (DoD) systems. CBM+ depends on the collection, processing and transport of large volumes of data. An important capability that enables CBM+ is an end-to-end network architecture that enables data to be uploaded from the platform at the tactical level to enterprise data analysis tools. To connect end-to-end maintenance processes in the Army's supply chain, a CBM+ network capability can be developed from available network capabilities.

  15. Operations Assessment of Launch Vehicle Architectures using Activity Based Cost Models

    NASA Technical Reports Server (NTRS)

    Ruiz-Torres, Alex J.; McCleskey, Carey

    2000-01-01

    The growing emphasis on affordability for space transportation systems requires the assessment of new space vehicles for all life cycle activities, from design and development, through manufacturing and operations. This paper addresses the operational assessment of launch vehicles, focusing on modeling the ground support requirements of a vehicle architecture, and estimating the resulting costs and flight rate. This paper proposes the use of Activity Based Costing (ABC) modeling for this assessment. The model uses expert knowledge to determine the activities, the activity times and the activity costs based on vehicle design characteristics. The approach provides several advantages to current approaches to vehicle architecture assessment including easier validation and allowing vehicle designers to understand the cost and cycle time drivers.

  16. Ultra-Fast Data-Mining Hardware Architecture Based on Stochastic Computing

    PubMed Central

    Oliver, Antoni; Alomar, Miquel L.

    2015-01-01

    Minimal hardware implementations able to cope with the processing of large amounts of data in reasonable times are highly desired in our information-driven society. In this work we review the application of stochastic computing to probabilistic-based pattern-recognition analysis of huge database sets. The proposed technique consists in the hardware implementation of a parallel architecture implementing a similarity search of data with respect to different pre-stored categories. We design pulse-based stochastic-logic blocks to obtain an efficient pattern recognition system. The proposed architecture speeds up the screening process of huge databases by a factor of 7 when compared to a conventional digital implementation using the same hardware area. PMID:25955274

  17. WebGIS based community services architecture by griddization managements and crowdsourcing services

    NASA Astrophysics Data System (ADS)

    Wang, Haiyin; Wan, Jianhua; Zeng, Zhe; Zhou, Shengchuan

    2016-11-01

    Along with the fast economic development of cities, rapid urbanization, population surge, in China, the social community service mechanisms need to be rationalized and the policy standards need to be unified, which results in various types of conflicts and challenges for community services of government. Based on the WebGIS technology, the article provides a community service architecture by gridding management and crowdsourcing service. The WEBGIS service architecture includes two parts: the cloud part and the mobile part. The cloud part refers to community service centres, which can instantaneously response the emergency, visualize the scene of the emergency, and analyse the data from the emergency. The mobile part refers to the mobile terminal, which can call the centre, report the event, collect data and verify the feedback. This WebGIS based community service systems for Huangdao District of Qingdao, were awarded the “2015’ national innovation of social governance case of typical cases”.

  18. Ultra-fast data-mining hardware architecture based on stochastic computing.

    PubMed

    Morro, Antoni; Canals, Vincent; Oliver, Antoni; Alomar, Miquel L; Rossello, Josep L

    2015-01-01

    Minimal hardware implementations able to cope with the processing of large amounts of data in reasonable times are highly desired in our information-driven society. In this work we review the application of stochastic computing to probabilistic-based pattern-recognition analysis of huge database sets. The proposed technique consists in the hardware implementation of a parallel architecture implementing a similarity search of data with respect to different pre-stored categories. We design pulse-based stochastic-logic blocks to obtain an efficient pattern recognition system. The proposed architecture speeds up the screening process of huge databases by a factor of 7 when compared to a conventional digital implementation using the same hardware area.

  19. [Web-based support system for medical device maintenance].

    PubMed

    Zhao, Jinhai; Hou, Wensheng; Chen, Haiyan; Tang, Wei; Wang, Yihui

    2015-01-01

    A Web-based technology system was put forward aiming at the actual problems of the long maintenance cycle and the difficulties of the maintenance and repairing of medical equipments. Based on analysis of platform system structure and function, using the key technologies such as search engine, BBS, knowledge base and etc, a platform for medical equipment service technician to use by online or offline was designed. The platform provides users with knowledge services and interactive services, enabling users to get a more ideal solution.

  20. Estimating and Measuring Application Latency of Typical Distributed Interactive Simulation (DIS)-Based Simulation Architecture

    DTIC Science & Technology

    2013-03-01

    analysis of state space consistency using a Petri net model (Hodson, 2009). 21 Figure 3: Producer, Network, and Consumer Models by Hodson...used a Petri net model to simulate a consumer/producer system to characterize the age of the state data. This research effort will use actual 24...software architecture, which is based on Hodson’s analysis of state space consistency using Petri net (Hodson, 2009). Figure 4: Multithreaded

  1. The middleware architecture supports heterogeneous network systems for module-based personal robot system

    NASA Astrophysics Data System (ADS)

    Choo, Seongho; Li, Vitaly; Choi, Dong Hee; Jung, Gi Deck; Park, Hong Seong; Ryuh, Youngsun

    2005-12-01

    On developing the personal robot system presently, the internal architecture is every module those occupy separated functions are connected through heterogeneous network system. This module-based architecture supports specialization and division of labor at not only designing but also implementation, as an effect of this architecture, it can reduce developing times and costs for modules. Furthermore, because every module is connected among other modules through network systems, we can get easy integrations and synergy effect to apply advanced mutual functions by co-working some modules. In this architecture, one of the most important technologies is the network middleware that takes charge communications among each modules connected through heterogeneous networks systems. The network middleware acts as the human nerve system inside of personal robot system; it relays, transmits, and translates information appropriately between modules that are similar to human organizations. The network middleware supports various hardware platform, heterogeneous network systems (Ethernet, Wireless LAN, USB, IEEE 1394, CAN, CDMA-SMS, RS-232C). This paper discussed some mechanisms about our network middleware to intercommunication and routing among modules, methods for real-time data communication and fault-tolerant network service. There have designed and implemented a layered network middleware scheme, distributed routing management, network monitoring/notification technology on heterogeneous networks for these goals. The main theme is how to make routing information in our network middleware. Additionally, with this routing information table, we appended some features. Now we are designing, making a new version network middleware (we call 'OO M/W') that can support object-oriented operation, also are updating program sources itself for object-oriented architecture. It is lighter, faster, and can support more operation systems and heterogeneous network systems, but other general

  2. Lidar detection of underwater objects using a neuro-SVM-based architecture.

    PubMed

    Mitra, Vikramjit; Wang, Chia-Jiu; Banerjee, Satarupa

    2006-05-01

    This paper presents a neural network architecture using a support vector machine (SVM) as an inference engine (IE) for classification of light detection and ranging (Lidar) data. Lidar data gives a sequence of laser backscatter intensities obtained from laser shots generated from an airborne object at various altitudes above the earth surface. Lidar data is pre-filtered to remove high frequency noise. As the Lidar shots are taken from above the earth surface, it has some air backscatter information, which is of no importance for detecting underwater objects. Because of these, the air backscatter information is eliminated from the data and a segment of this data is subsequently selected to extract features for classification. This is then encoded using linear predictive coding (LPC) and polynomial approximation. The coefficients thus generated are used as inputs to the two branches of a parallel neural architecture. The decisions obtained from the two branches are vector multiplied and the result is fed to an SVM-based IE that presents the final inference. Two parallel neural architectures using multilayer perception (MLP) and hybrid radial basis function (HRBF) are considered in this paper. The proposed structure fits the Lidar data classification task well due to the inherent classification efficiency of neural networks and accurate decision-making capability of SVM. A Bayesian classifier and a quadratic classifier were considered for the Lidar data classification task but they failed to offer high prediction accuracy. Furthermore, a single-layered artificial neural network (ANN) classifier was also considered and it failed to offer good accuracy. The parallel ANN architecture proposed in this paper offers high prediction accuracy (98.9%) and is found to be the most suitable architecture for the proposed task of Lidar data classification.

  3. Development of Network-based Communications Architectures for Future NASA Missions

    NASA Technical Reports Server (NTRS)

    Slywczak, Richard A.

    2007-01-01

    Since the Vision for Space Exploration (VSE) announcement, NASA has been developing a communications infrastructure that combines existing terrestrial techniques with newer concepts and capabilities. The overall goal is to develop a flexible, modular, and extensible architecture that leverages and enhances terrestrial networking technologies that can either be directly applied or modified for the space regime. In addition, where existing technologies leaves gaps, new technologies must be developed. An example includes dynamic routing that accounts for constrained power and bandwidth environments. Using these enhanced technologies, NASA can develop nodes that provide characteristics, such as routing, store and forward, and access-on-demand capabilities. But with the development of the new infrastructure, challenges and obstacles will arise. The current communications infrastructure has been developed on a mission-by-mission basis rather than an end-to-end approach; this has led to a greater ground infrastructure, but has not encouraged communications between space-based assets. This alone provides one of the key challenges that NASA must encounter. With the development of the new Crew Exploration Vehicle (CEV), NASA has the opportunity to provide an integration path for the new vehicles and provide standards for their development. Some of the newer capabilities these vehicles could include are routing, security, and Software Defined Radios (SDRs). To meet these needs, the NASA/Glenn Research Center s (GRC) Network Emulation Laboratory (NEL) has been using both simulation and emulation to study and evaluate these architectures. These techniques provide options to NASA that directly impact architecture development. This paper identifies components of the infrastructure that play a pivotal role in the new NASA architecture, develops a scheme using simulation and emulation for testing these architectures and demonstrates how NASA can strengthen the new infrastructure by

  4. Problem-Based Learning Case Writing in Medical Science.

    ERIC Educational Resources Information Center

    Agbor-Baiyee, William

    It is common practice in problem-based learning for students to solve cases developed by faculty. Rare is the practice of creating learning environments in which students construct their own cases. This paper examines the design and implementation of a 15-week problem-based learning writing course for graduate students in medical science. The…

  5. Teaching Evidence-based Medical Care: Description and Evaluation.

    ERIC Educational Resources Information Center

    Grad, Roland; Macaulay, Ann C.; Warner, Michelle

    2001-01-01

    Describes and evaluates a teaching initiative in evidence-based medical care in McGill University's family practice residency program. Discusses results of pre- and post-course self-assessments by students, which indicated significant increases in skill at formulating clinical questions and searching for evidence-based answers, appraising reviews,…

  6. Lunar Outpost Life Support Architecture Study Based on a High Mobility Exploration Scenario

    NASA Technical Reports Server (NTRS)

    Lange, Kevin E.; Anderson, Molly S.

    2009-01-01

    As scenarios for lunar surface exploration and habitation continue to evolve within NASA s Constellation program, so must studies of optimal life support system architectures and technologies. This paper presents results of a life support architecture study based on a 2009 NASA scenario known as Scenario 12. Scenario 12 represents a consolidation of ideas from earlier NASA scenarios and includes an outpost near the Lunar South Pole comprised of three larger fixed surface elements and four attached pressurized rovers. The scenario places a high emphasis on surface mobility, with planning assuming that all four crewmembers spend roughly 50% of the time away from the outpost on 3-14 day excursions in two of the pressurized rovers. Some of the larger elements can also be mobilized for longer duration excursions. This emphasis on mobility poses a significant challenge for a regenerative life support system in terms of cost-effective waste collection and resource recovery across multiple elements, including rovers with very constrained infrastructure resources. The current study considers pressurized rovers as part of a distributed outpost life support architecture in both stand-alone and integrated configurations. A range of architectures are examined reflecting different levels of closure and distributed functionality. Different lander propellant scavenging options are also considered involving either initial conversion of residual oxygen and hydrogen propellants to water or initial direct oxygen scavenging. Monte Carlo simulations are used to assess the sensitivity of results to volatile high-impact mission variables, including the quantity of residual lander propellants available for scavenging, the fraction of crew time away from the outpost on excursions, total extravehicular activity hours, and habitat leakage. Architectures are evaluated by estimating surpluses or deficits of water and oxygen per 180-day mission and differences in fixed and 10-year

  7. Efficiency and Scalability of Barrier Synchronization on NoC Based Many-core Architectures

    SciTech Connect

    Villa, Oreste; Palermo, Gianluca; Silvano, Cristina

    2008-10-18

    Interconnects based on Networks-on-Chip are an appealing solution to address future microprocessor designs where, very likely, hundreds of cores will be connected on a single chip. A fundamental role in highly parallelized applications running on many-core architectures will be played by barrier primitives used to synchronize the execution of parallel processes. This paper focuses on the analysis of the efficiency and scalability of different barrier implementations in many-core architectures based on NoCs. Several message passing barrier implementations based on four algorithms (all-to-all, master-slave, butterfly and tree) have been implemented and evaluated for a single-chip target architecture composed of a variable number of cores (from 4 to 128) and different network topologies (mesh, torus, ring, clustered-ring and fat-tree). Using a cycle-accurate simulator, we show the scalability of each barrier for every NoC topology, analyzing and comparing theoretical with real behaviors. We observed that some barrier algorithms, when implemented in hardware or software, show a different scaling behavior with respect to those theoretically expected. We evaluate the efficiency of each combination topology-barrier, demonstrating that, in many cases, simple network topologies can be more efficient than complex and highly connected topologies.

  8. SAL: a language for developing an agent-based architecture for mobile robots

    NASA Astrophysics Data System (ADS)

    Lim, Willie Y.; Verzulli, Joe

    1993-05-01

    SAL (the SmartyCat Agent Language) is a language being developed for programming SmartyCat, our mobile robot. SmartyCat's underlying software architecture is agent-based. At the lowest level, the robot sensors and actuators are controlled by agents (viz., the sensing and acting agents, respectively). SAL provides the constructs for organizing these agents into many structures. In particular, SAL supports the subsumption architecture approach. At higher levels of abstraction, SAL can be used for writing programs based on Minsky's Society of Mind paradigm. Structurally, a SAL program is a graph, where the nodes are software modules called agents, and the arcs represent abstract communication links between agents. In SAL, an agent is a CLOS object with input and output ports. Input ports are used for presenting data from the outside world (i.e., other agents) to the agent. Data are presented to the outside world by the agent through its output ports. The main body of the SAL code for the agent specifies the computation or the action performed by the agent. This paper describes how SAL is being used for implementing the agent-based SmartyCat software architecture on a Cybermotion K2A platform.

  9. Characterization of Model-Based Reasoning Strategies for Use in IVHM Architectures

    NASA Technical Reports Server (NTRS)

    Poll, Scott; Iverson, David; Patterson-Hine, Ann

    2003-01-01

    Open architectures are gaining popularity for Integrated Vehicle Health Management (IVHM) applications due to the diversity of subsystem health monitoring strategies in use and the need to integrate a variety of techniques at the system health management level. The basic concept of an open architecture suggests that whatever monitoring or reasoning strategy a subsystem wishes to deploy, the system architecture will support the needs of that subsystem and will be capable of transmitting subsystem health status across subsystem boundaries and up to the system level for system-wide fault identification and diagnosis. There is a need to understand the capabilities of various reasoning engines and how they, coupled with intelligent monitoring techniques, can support fault detection and system level fault management. Researchers in IVHM at NASA Ames Research Center are supporting the development of an IVHM system for liquefying-fuel hybrid rockets. In the initial stage of this project, a few readily available reasoning engines were studied to assess candidate technologies for application in next generation launch systems. Three tools representing the spectrum of model-based reasoning approaches, from a quantitative simulation based approach to a graph-based fault propagation technique, were applied to model the behavior of the Hybrid Combustion Facility testbed at Ames. This paper summarizes the characterization of the modeling process for each of the techniques.

  10. The Nomad Explorer assembly assist vehicle: An architecture for rapid global extraterrestrial base infrastructure establishment

    NASA Technical Reports Server (NTRS)

    Thangavelu, Madhu

    1994-01-01

    Traditional concepts of lunar bases describe scenarios where components of the bases are landed on the lunar surface, one at a time, and then put together to form a complete stationary lunar habitat. Recently, some concepts have described the advantages of operating a mobile or 'roving' lunar base. Such a base vastly improves the exploration range from a primary lunar base. Roving bases would also allow the crew to first deploy, test, operationally certify, and then regularly maintain, service, and evolve long life-cycle facilities like observatories or other science payload platforms that are operated far apart from each other across the extraterrestrial surface. The Nomad Explorer is such a mobile lunar base. This paper describes the architectural program of the Nomad Explorer, its advantages over a stationary lunar base, and some of the embedded system concepts which help the roving base to speedily establish a global extraterrestrial infrastructure. A number of modular autonomous logistics landers will carry deployable or erectable payloads, service, and logistically resupply the Nomad Explorer at regular intercepts along the traverse. Starting with the deployment of science experiments and telecommunication networks, and the manned emplacement of a variety of remote outposts using a unique EVA Bell system that enhances manned EVA, the Nomad Explorer architecture suggests the capability for a rapid global development of the extraterrestrial body. The Moon and Mars are candidates for this 'mission oriented' strategy. The lunar case is emphasized in this paper.

  11. Evidence-Based Heart Failure Medications and Cognition

    PubMed Central

    Bratzke, Lisa C.; Moser, Debra K.; Pelter, Michele M.; Paul, Steven M.; Nesbitt, Thomas S.; Cooper, Lawton S.; Dracup, Kathleen A.

    2014-01-01

    Background The etiology of cognitive impairment in heart failure (HF) is controversial and likely multifactorial. Physicians may hesitate to prescribe evidence-based HF medication because of concerns related to potential negative changes in cognition among a population that is already frequently impaired. We conducted a study to determine if prescription of evidence-based HF medications (specifically, beta-blockers, angiotensin-converting enzyme inhibitors, angiotensin-receptor blocking agents, diuretics, and aldosterone inhibitors) was associated with cognition in a large HF sample. Methods Six-hundred and twelve patients completed baseline data collection for the Rural Education to improve OuTcomEs in Heart Failure clinical trial (REMOTE-HF), including information about medications. Global cognition was evaluated using the Mini-Cog. Results The sample mean age was 66-years old (SD 13 years), 58% were male, 89% Caucasian. Global cognitive impairment was identified in 206 (34%) of the 612 patients. Prescription of evidence-based HF medications was not related to global cognitive impairment in this sample. This relationship was maintained even after adjusting for potential confounders (e.g. age, education, and comorbid burden). Conclusion Prescription of evidence-based HF medications is not related to low scores of a measure of global cognitive function in rural patients with HF. PMID:25419943

  12. An Architecture and Supporting Environment of Service-Oriented Computing Based-On Context Awareness

    NASA Astrophysics Data System (ADS)

    Ma, Tianxiao; Wu, Gang; Huang, Jun

    Service-oriented computing (SOC) is emerging to be an important computing paradigm of the next future. Based on context awareness, this paper proposes an architecture of SOC. A definition of the context in open environments such as Internet is given, which is based on ontology. The paper also proposes a supporting environment for the context-aware SOC, which focus on services on-demand composition and context-awareness evolving. A reference implementation of the supporting environment based on OSGi[11] is given at last.

  13. Tele-medical imaging conference system based on the Web.

    PubMed

    Choi, Heung-Kook; Park, Se-Myung; Kang, Jae-Hyo; Kim, Sang-Kyoon; Choi, Hang-Mook

    2002-06-01

    In this paper, a medical imaging conference system is presented, which is carried out in the Web environment using the distributed object technique, CORBA. Independent of platforms and different developing languages, the CORBA-based medical imaging conference system is very powerful for system development, extension and maintenance. With this Web client/server, one could easily execute a medical imaging conference using Applets on the Web. The Java language, which is object-oriented and independent of platforms, has the advantage of free usage wherever the Web browser is. By using the proposed system, we envisage being able to open a tele-conference using medical images, e.g. CT, MRI, X-ray etc., easily and effectively among remote hospitals.

  14. Curing neurophobia in medical schools: evidence-based strategies

    PubMed Central

    Abushouk, Abdelrahman Ibrahim; Duc, Nguyen Minh

    2016-01-01

    Medical students often perceive neurology as the most difficult medical specialty. This perception is described as ‘neurophobia’ in the medical literature. Several studies have cited poor teaching, complex examination, and separation of basic and clinical sciences as major factors in the development of neurophobia. These negative perceptions can have serious implications, such as decreasing the students’ desire to consider neurology as a future career and increasing referrals from other specialists to avoid dealing with neurological conditions. Faced with increasing demands of healthcare systems and the global burden of neurological conditions, there is a rising need for further research and innovative strategies to improve students’ perceptions of clinical neurology. This review discusses evidence-based recommendations and educational interventions to cure neurophobia in medical education. PMID:27680578

  15. Web-based medical facilitators in medical tourism: the third party in decision-making.

    PubMed

    Wagle, Suchitra

    2013-01-01

    The emergence of web-based medical tourism facilitators (MTFs) has added a new dimension to the phenomenon of cross-border travel. These facilitators are crucial connectors between foreign patients and host countries. They help patients navigate countries, doctors and specialties. However, little attention has been paid to the authenticity of information displayed on the facilitators' web portals, and whether they follow ethical guidelines and standards. This paper analyses the available information on MTF portals from an ethics perspective. It compares 208 facilitators across 47 countries for the services offered. Data were collected from the databases of the Medical Tourism Association and World Medical Resources. India was the most common destination country linked to 81 facilitators. The five countries with the maximum number of facilitators were the USA, the UK, India, Canada and Poland. This paper identifies concerns regarding the information displayed about patients' safety, and the maintenance of confidentiality. There is a need to develop ethical standards for this field.

  16. Graphene-based macroscopic assemblies and architectures: an emerging material system.

    PubMed

    Cong, Huai-Ping; Chen, Jia-Fu; Yu, Shu-Hong

    2014-11-07

    Due to the outstanding physicochemical properties arising from its truly two-dimensional (2D) planar structure with a single-atom thickness, graphene exhibits great potential for use in sensors, catalysts, electrodes, and in biological applications, etc. With further developments in the theoretical understanding and assembly techniques, graphene should enable great changes both in scientific research and practical industrial applications. By the look of development, it is of fundamental and practical significance to translate the novel physical and chemical properties of individual graphene nanosheets into the macroscale by the assembly of graphene building blocks into macroscopic architectures with structural specialities and functional novelties. The combined features of a 2D planar structure and abundant functional groups of graphene oxide (GO) should provide great possibilities for the assembly of GO nanosheets into macroscopic architectures with different macroscaled shapes through various assembly techniques under different bonding interactions. Moreover, macroscopic graphene frameworks can be used as ideal scaffolds for the incorporation of functional materials to offset the shortage of pure graphene in the specific desired functionality. The advantages of light weight, supra-flexibility, large surface area, tough mechanical strength, and high electrical conductivity guarantee graphene-based architectures wide application fields. This critical review mainly addresses recent advances in the design and fabrication of graphene-based macroscopic assemblies and architectures and their potential applications. Herein, we first provide overviews of the functional macroscopic graphene materials from three aspects, i.e., 1D graphene fibers/ribbons, 2D graphene films/papers, 3D network-structured graphene monoliths, and their composite counterparts with either polymers or nano-objects. Then, we present the promising potential applications of graphene-based macroscopic

  17. Medical Device Integration Model Based on the Internet of Things

    PubMed Central

    Hao, Aiyu; Wang, Ling

    2015-01-01

    At present, hospitals in our country have basically established the HIS system, which manages registration, treatment, and charge, among many others, of patients. During treatment, patients need to use medical devices repeatedly to acquire all sorts of inspection data. Currently, the output data of the medical devices are often manually input into information system, which is easy to get wrong or easy to cause mismatches between inspection reports and patients. For some small hospitals of which information construction is still relatively weak, the information generated by the devices is still presented in the form of paper reports. When doctors or patients want to have access to the data at a given time again, they can only look at the paper files. Data integration between medical devices has long been a difficult problem for the medical information system, because the data from medical devices are lack of mandatory unified global standards and have outstanding heterogeneity of devices. In order to protect their own interests, manufacturers use special protocols, etc., thus causing medical decices to still be the "lonely island" of hospital information system. Besides, unfocused application of the data will lead to failure to achieve a reasonable distribution of medical resources. With the deepening of IT construction in hospitals, medical information systems will be bound to develop towards mobile applications, intelligent analysis, and interconnection and interworking, on the premise that there is an effective medical device integration (MDI) technology. To this end, this paper presents a MDI model based on the Internet of Things (IoT). Through abstract classification, this model is able to extract the common characteristics of the devices, resolve the heterogeneous differences between them, and employ a unified protocol to integrate data between devices. And by the IoT technology, it realizes interconnection network of devices and conducts associate matching

  18. Medical Device Integration Model Based on the Internet of Things.

    PubMed

    Hao, Aiyu; Wang, Ling

    2015-01-01

    At present, hospitals in our country have basically established the HIS system, which manages registration, treatment, and charge, among many others, of patients. During treatment, patients need to use medical devices repeatedly to acquire all sorts of inspection data. Currently, the output data of the medical devices are often manually input into information system, which is easy to get wrong or easy to cause mismatches between inspection reports and patients. For some small hospitals of which information construction is still relatively weak, the information generated by the devices is still presented in the form of paper reports. When doctors or patients want to have access to the data at a given time again, they can only look at the paper files. Data integration between medical devices has long been a difficult problem for the medical information system, because the data from medical devices are lack of mandatory unified global standards and have outstanding heterogeneity of devices. In order to protect their own interests, manufacturers use special protocols, etc., thus causing medical decices to still be the "lonely island" of hospital information system. Besides, unfocused application of the data will lead to failure to achieve a reasonable distribution of medical resources. With the deepening of IT construction in hospitals, medical information systems will be bound to develop towards mobile applications, intelligent analysis, and interconnection and interworking, on the premise that there is an effective medical device integration (MDI) technology. To this end, this paper presents a MDI model based on the Internet of Things (IoT). Through abstract classification, this model is able to extract the common characteristics of the devices, resolve the heterogeneous differences between them, and employ a unified protocol to integrate data between devices. And by the IoT technology, it realizes interconnection network of devices and conducts associate matching

  19. Case-based seminars in medical ethics education: how medical students define and discuss moral problems.

    PubMed

    Donaldson, Thomas M; Fistein, Elizabeth; Dunn, Michael

    2010-12-01

    Discussion of real cases encountered by medical students has been advocated as a component of medical ethics education. Suggested benefits include: a focus on the actual problems that medical students confront; active learner involvement; and facilitation of an exploration of the meaning of their own values in relation to professional behaviour. However, the approach may also carry risks: students may focus too narrowly on particular clinical topics or show a preference for discussing legal problems that may appear to have clearer solutions. Teaching may therefore omit areas generally considered to be important components of the curriculum. In this paper, the authors present an analysis of the moral problems raised by medical students in response to a request to describe ethically problematic cases they had encountered during two clinical attachments, for the purpose of educational discussion at case-based seminars. We discuss the problems raised and compare the content of the cases to the UK Consensus Statement on core content of learning. The authors also describe the approaches that the students used to undertake an initial analysis of the problems raised, and consider possible implications for the development of medical ethics education.

  20. A hypermedia-based medical records management system.

    PubMed

    Laforest, F; Frénot, S; Flory, A

    1998-01-01

    This article presents a new way to manage computerized medical records, based on a totally-hypermedia system. As a matter of fact, the classical use of a database limits the necessary variability of the medical record, in function of both the patient profile and the care practitioner habits. The system we propose is based on a hospital Intranet, and on the XML language. This language allows the definition of semantic tags in hyperdocuments, and thus information retrieval is ensured through semantic tags indexation.

  1. Desiderata for Healthcare Integrated Data Repositories Based on Architectural Comparison of Three Public Repositories

    PubMed Central

    Huser, Vojtech; Cimino, James J.

    2013-01-01

    Integrated data repositories (IDRs) are indispensable tools for numerous biomedical research studies. We compare three large IDRs (Informatics for Integrating Biology and the Bedside (i2b2), HMO Research Network’s Virtual Data Warehouse (VDW) and Observational Medical Outcomes Partnership (OMOP) repository) in order to identify common architectural features that enable efficient storage and organization of large amounts of clinical data. We define three high-level classes of underlying data storage models and we analyze each repository using this classification. We look at how a set of sample facts is represented in each repository and conclude with a list of desiderata for IDRs that deal with the information storage model, terminology model, data integration and value-sets management. PMID:24551366

  2. A healthcare management system for Turkey based on a service-oriented architecture.

    PubMed

    Herand, Deniz; Gürder, Filiz; Taşkin, Harun; Yuksel, Emre Nuri

    2013-09-01

    The current Turkish healthcare management system has a structure that is extremely inordinate, cumbersome and inflexible. Furthermore, this structure has no common point of view and thus has no interoperability and responds slowly to innovations. The purpose of this study is to show that using which methods can the Turkish healthcare management system provide a structure that could be more modern, more flexible and more quick to respond to innovations and changes taking advantage of the benefits given by a service-oriented architecture (SOA). In this paper, the Turkish healthcare management system is chosen to be examined since Turkey is considered as one of the Third World countries and the information architecture of the existing healthcare management system of Turkey has not yet been configured with SOA, which is a contemporary innovative approach and should provide the base architecture of the new solution. The innovation of this study is the symbiosis of two main integration approaches, SOA and Health Level 7 (HL7), for integrating divergent healthcare information systems. A model is developed which is based on SOA and enables obtaining a healthcare management system having the SSF standards (HSSP Service Specification Framework) developed by the framework of the HSSP (Healthcare Services Specification Project) under the leadership of HL7 and the Object Management Group.

  3. The architecture of an event correlation service for adaptive middleware-based applications

    SciTech Connect

    Liu, Yan; Gorton, Ian; Lee, Vinh Kah

    2008-12-01

    Loosely coupled component communication driven by events is a key mechanism for building middleware- based applications that must achieve reliable qualities of service in an adaptive manner. In such a system, events that encapsulate state snapshots of a running system are generated by monitoring components. Hence, an event correlation service is necessary for correlating monitored events from multiple sources. The requirements for the event correlation raise two challenges: to seamlessly integrate event correlation services with other services and applications; and to provide reliable event management with minimal delay. This paper describes our experience in the design and implementation of an event correlation service. The design encompasses an event correlator and an event proxy that are integrated with an architecture for adaptive middleware components. The implementation utilizes the common-based event (CBE) specification and stateful Web service technologies to support the deployment of the event correlation service in a distributed architecture. We evaluate the performance of the overall solution in a test bed and present the results in terms of the trade-off between the flexibility and the performance overhead of the architecture

  4. Bio-signal analysis system design with support vector machines based on cloud computing service architecture.

    PubMed

    Shen, Chia-Ping; Chen, Wei-Hsin; Chen, Jia-Ming; Hsu, Kai-Ping; Lin, Jeng-Wei; Chiu, Ming-Jang; Chen, Chi-Huang; Lai, Feipei

    2010-01-01

    Today, many bio-signals such as Electroencephalography (EEG) are recorded in digital format. It is an emerging research area of analyzing these digital bio-signals to extract useful health information in biomedical engineering. In this paper, a bio-signal analyzing cloud computing architecture, called BACCA, is proposed. The system has been designed with the purpose of seamless integration into the National Taiwan University Health Information System. Based on the concept of. NET Service Oriented Architecture, the system integrates heterogeneous platforms, protocols, as well as applications. In this system, we add modern analytic functions such as approximated entropy and adaptive support vector machine (SVM). It is shown that the overall accuracy of EEG bio-signal analysis has increased to nearly 98% for different data sets, including open-source and clinical data sets.

  5. Architectural Analysis of Systems Based on the Publisher-Subscriber Style

    NASA Technical Reports Server (NTRS)

    Ganesun, Dharmalingam; Lindvall, Mikael; Ruley, Lamont; Wiegand, Robert; Ly, Vuong; Tsui, Tina

    2010-01-01

    Architectural styles impose constraints on both the topology and the interaction behavior of involved parties. In this paper, we propose an approach for analyzing implemented systems based on the publisher-subscriber architectural style. From the style definition, we derive a set of reusable questions and show that some of them can be answered statically whereas others are best answered using dynamic analysis. The paper explains how the results of static analysis can be used to orchestrate dynamic analysis. The proposed method was successfully applied on the NASA's Goddard Mission Services Evolution Center (GMSEC) software product line. The results show that the GMSEC has a) a novel reusable vendor-independent middleware abstraction layer that allows the NASA's missions to configure the middleware of interest without changing the publishers' or subscribers' source code, and b) some high priority bugs due to behavioral discrepancies, which were eluded during testing and code reviews, among different implementations of the same APIs for different vendors.

  6. A Web of Things-Based Emerging Sensor Network Architecture for Smart Control Systems.

    PubMed

    Khan, Murad; Silva, Bhagya Nathali; Han, Kijun

    2017-02-09

    The Web of Things (WoT) plays an important role in the representation of the objects connected to the Internet of Things in a more transparent and effective way. Thus, it enables seamless and ubiquitous web communication between users and the smart things. Considering the importance of WoT, we propose a WoT-based emerging sensor network (WoT-ESN), which collects data from sensors, routes sensor data to the web, and integrate smart things into the web employing a representational state transfer (REST) architecture. A smart home scenario is introduced to evaluate the proposed WoT-ESN architecture. The smart home scenario is tested through computer simulation of the energy consumption of various household appliances, device discovery, and response time performance. The simulation results show that the proposed scheme significantly optimizes the energy consumption of the household appliances and the response time of the appliances.

  7. Providing conceptual framework support for distributed Web-based simulation within the high-level architecture

    NASA Astrophysics Data System (ADS)

    Page, Ernest H.; Griffin, Sean P.; Rother, S. L.

    1998-08-01

    Web-based simulation, a subject of increasing interest to both simulation researchers and practitioners, has the potential to significantly influence the application and availability of simulation as a problem-solving technique. Web technologies also portend cost-effective distributed modeling and simulation. These applications will require solutions to the systems interoperability problem similar to the DoD High Level Architecture (HLA). The suitability of the HLA to serve 'mainstream' simulation is examined.Approaches for incorporating discrete event simulation conceptual frameworks within the HLA are described and ongoing research in this area noted. Issues raised include a discussion of the appropriate roles for a simulation-support language and a simulation-support architecture.

  8. A Web of Things-Based Emerging Sensor Network Architecture for Smart Control Systems

    PubMed Central

    Khan, Murad; Silva, Bhagya Nathali; Han, Kijun

    2017-01-01

    The Web of Things (WoT) plays an important role in the representation of the objects connected to the Internet of Things in a more transparent and effective way. Thus, it enables seamless and ubiquitous web communication between users and the smart things. Considering the importance of WoT, we propose a WoT-based emerging sensor network (WoT-ESN), which collects data from sensors, routes sensor data to the web, and integrate smart things into the web employing a representational state transfer (REST) architecture. A smart home scenario is introduced to evaluate the proposed WoT-ESN architecture. The smart home scenario is tested through computer simulation of the energy consumption of various household appliances, device discovery, and response time performance. The simulation results show that the proposed scheme significantly optimizes the energy consumption of the household appliances and the response time of the appliances.  PMID:28208787

  9. Usage based indicators to assess the impact of scholarly works: architecture and method

    DOEpatents

    Bollen, Johan [Santa Fe, NM; Van De Sompel, Herbert [Santa Fe, NM

    2012-03-13

    Although recording of usage data is common in scholarly information services, its exploitation for the creation of value-added services remains limited due to concerns regarding, among others, user privacy, data validity, and the lack of accepted standards for the representation, sharing and aggregation of usage data. A technical, standards-based architecture for sharing usage information is presented. In this architecture, OpenURL-compliant linking servers aggregate usage information of a specific user community as it navigates the distributed information environment that it has access to. This usage information is made OAI-PMH harvestable so that usage information exposed by many linking servers can be aggregated to facilitate the creation of value-added services with a reach beyond that of a single community or a single information service.

  10. A Supply Chain Architecture Based on Multi-agent Systems to Support Decentralized Collaborative Processes

    NASA Astrophysics Data System (ADS)

    Hernández, Jorge E.; Poler, Raúl; Mula, Josefa

    In a supply chain management context, the enterprise architecture concept to efficiently support the collaborative processes among the supply chain members involved has been evolving. Each supply chain has an organizational structure that describes the hierarchical relationships among its members, ranging from centralized to decentralized organizations. From a decentralized perspective, each supply chain member is able to identify collaborative and non collaborative partners and the kind of information to be exchanged to support negotiation processes. The same concepts of organizational structure and negotiation rules can be applied to a multi-agent system. This paper proposes a novel supply chain architecture to support decentralized collaborative processes in supply chains by considering a multi-agent-based system modeling approach.

  11. Phased Array-Fed Reflector (PAFR) Antenna Architectures for Space-Based Sensors

    NASA Technical Reports Server (NTRS)

    Cooley, Michael E.

    2014-01-01

    Communication link and target ranges for satellite communications (SATCOM) and space-based sensors (e.g. radars) vary from approximately 1000 km (for LEO satellites) to 35,800 km (for GEO satellites). At these long ranges, large antenna gains are required and legacy payloads have usually employed large reflectors with single beams that are either fixed or mechanically steered. For many applications, there are inherent limitations that are associated with the use of these legacy antennas/payloads. Hybrid antenna designs using Phased Array Fed Reflectors (PAFRs) provide a compromise between reflectors and Direct Radiating phased Arrays (DRAs). PAFRs provide many of the performance benefits of DRAs while utilizing much smaller, lower cost (feed) arrays. The primary limitation associated with hybrid PAFR architectures is electronic scan range; approximately +/-5 to +/- 10 degrees is typical, but this range depends on many factors. For LEO applications, the earth FOV is approximately +/-55 degrees which is well beyond the range of electronic scanning for PAFRs. However, for some LEO missions, limited scanning is sufficient or the CONOPS and space vehicle designs can be developed to incorporate a combination mechanical slewing and electronic scanning. In this paper, we review, compare and contrast various PAFR architectures with a focus on their general applicability to space missions. We compare the RF performance of various PAFR architectures and describe key hardware design and implementation trades. Space-based PAFR designs are highly multi-disciplinary and we briefly address key hardware engineering design areas. Finally, we briefly describe two PAFR antenna architectures that have been developed at Northrop Grumman.

  12. [P.A.I.S., a personal medical information system. A comprehensive medical knowledge base].

    PubMed

    Münch, E

    1994-06-01

    The electronic medical knowledge data base DOPIS is a compliation of knowledge from various special fields of medicine. Using uniform nomenclature, the data are presented on demand as they would be in a book chapter. Concise updates can be performed at low cost. The primary structure of the concept is the division of medical knowledge into data banks on diagnosis, literature, medication and pharmacology, as well as so-called electronic textbooks. All data banks and electronic textbooks are connected associatively. Visual information is obtained via the image data bank connected to the diagnosis data bank and the electronic books. Moreover, DOPIS has an integrated patient findings system, as well as an image processing and archiving system with research values enabling research functions. The diagnosis and literature data banks can be modified by the user or author, or fed with their own data (a so-called Expert System Shell). For authors from special fields working on the project, an extra Medical Electronic Publishing System has been developed and made available for the electronic textbooks. The model for the knowledge data base has been developed in the field of ENT, the programme implemented and initially ENT data have been stored.

  13. Data Parallel Bin-Based Indexing for Answering Queries on Multi-Core Architectures

    SciTech Connect

    Gosink, Luke; Wu, Kesheng; Bethel, E. Wes; Owens, John D.; Joy, Kenneth I.

    2009-06-02

    The multi-core trend in CPUs and general purpose graphics processing units (GPUs) offers new opportunities for the database community. The increase of cores at exponential rates is likely to affect virtually every server and client in the coming decade, and presents database management systems with a huge, compelling disruption that will radically change how processing is done. This paper presents a new parallel indexing data structure for answering queries that takes full advantage of the increasing thread-level parallelism emerging in multi-core architectures. In our approach, our Data Parallel Bin-based Index Strategy (DP-BIS) first bins the base data, and then partitions and stores the values in each bin as a separate, bin-based data cluster. In answering a query, the procedures for examining the bin numbers and the bin-based data clusters offer the maximum possible level of concurrency; each record is evaluated by a single thread and all threads are processed simultaneously in parallel. We implement and demonstrate the effectiveness of DP-BIS on two multi-core architectures: a multi-core CPU and a GPU. The concurrency afforded by DP-BIS allows us to fully utilize the thread-level parallelism provided by each architecture--for example, our GPU-based DP-BIS implementation simultaneously evaluates over 12,000 records with an equivalent number of concurrently executing threads. In comparing DP-BIS's performance across these architectures, we show that the GPU-based DP-BIS implementation requires significantly less computation time to answer a query than the CPU-based implementation. We also demonstrate in our analysis that DP-BIS provides better overall performance than the commonly utilized CPU and GPU-based projection index. Finally, due to data encoding, we show that DP-BIS accesses significantly smaller amounts of data than index strategies that operate solely on a column's base data; this smaller data footprint is critical for parallel processors that possess

  14. Architectural design proposal for a Martian base to continue NASA Mars Design Reference Mission

    NASA Astrophysics Data System (ADS)

    Kozicki, Janek

    The issue of extraterrestrial bases has recently been a very vivid one. There are orbital stations currently existing and humans will travel to Mars around 2030. They will need stations established there, which will provide them the proper living conditions. Firstly, it might be a small module brought from Earth (e.g. NASA Mars Design Reference Mission module (DRM)), in later stages equivalents of Earth houses may be built from local resources. The goal of this paper is to propose an architectural design for an intermediate stage — for a larger habitable unit transported from Earth. It is inspired by terrestrial portable architecture ideas. A pneumatic structure requires small volume during transportation. However, it provides large habitable space after deployment. It is designed for transport by DRM transportation module and its deployment is considerable easy and brief. An architectural solution analogous to a terrestrial house with a studio and a workshop was assumed. Its form was a result of technical and environmental limitations, and the need for an ergonomic interior. The spatial placement of following zones was carefully considered: residential, agricultural and science, as well as a garage with a workshop, transportation routes, and a control and communication center. The issues of Life Support System, energy, food, water and waste recycling were also discussed. This Martian base was designed to be crewed by a team of eight people to stay on Mars for at least 1.5 year. An Open Plan architectural solution was assumed in pneumatic modules, with a high level of modularity. Walls of standardized sizes with zip-fasteners allow free rearrangement of the interior to adapt to a new situation (e.g. damage of one of the pneumatic modules or a psychological ,,need of a change"). The architectural design focuses on ergonomic and psychological aspects of longer stay in hostile Martian environment. This solution provides Martian crew with a comfortable habitable

  15. Performance optimization of web-based medical simulation.

    PubMed

    Halic, Tansel; Ahn, Woojin; De, Suvranu

    2013-01-01

    This paper presents a technique for performance optimization of multimodal interactive web-based medical simulation. A web-based simulation framework is promising for easy access and wide dissemination of medical simulation. However, the real-time performance of the simulation highly depends on hardware capability on the client side. Providing consistent simulation in different hardware is critical for reliable medical simulation. This paper proposes a non-linear mixed integer programming model to optimize the performance of visualization and physics computation while considering hardware capability and application specific constraints. The optimization model identifies and parameterizes the rendering and computing capabilities of the client hardware using an exploratory proxy code. The parameters are utilized to determine the optimized simulation conditions including texture sizes, mesh sizes and canvas resolution. The test results show that the optimization model not only achieves a desired frame per second but also resolves visual artifacts due to low performance hardware.

  16. Medical image compression algorithm based on wavelet transform

    NASA Astrophysics Data System (ADS)

    Chen, Minghong; Zhang, Guoping; Wan, Wei; Liu, Minmin

    2005-02-01

    With rapid development of electronic imaging and multimedia technology, the telemedicine is applied to modern medical servings in the hospital. Digital medical image is characterized by high resolution, high precision and vast data. The optimized compression algorithm can alleviate restriction in the transmission speed and data storage. This paper describes the characteristics of human vision system based on the physiology structure, and analyses the characteristics of medical image in the telemedicine, then it brings forward an optimized compression algorithm based on wavelet zerotree. After the image is smoothed, it is decomposed with the haar filters. Then the wavelet coefficients are quantified adaptively. Therefore, we can maximize efficiency of compression and achieve better subjective visual image. This algorithm can be applied to image transmission in the telemedicine. In the end, we examined the feasibility of this algorithm with an image transmission experiment in the network.

  17. Designing protein-based biomaterials for medical applications.

    PubMed

    Gagner, Jennifer E; Kim, Wookhyun; Chaikof, Elliot L

    2014-04-01

    Biomaterials produced by nature have been honed through billions of years, evolving exquisitely precise structure-function relationships that scientists strive to emulate. Advances in genetic engineering have facilitated extensive investigations to determine how changes in even a single peptide within a protein sequence can produce biomaterials with unique thermal, mechanical and biological properties. Elastin, a naturally occurring protein polymer, serves as a model protein to determine the relationship between specific structural elements and desirable material characteristics. The modular, repetitive nature of the protein facilitates the formation of well-defined secondary structures with the ability to self-assemble into complex three-dimensional architectures on a variety of length scales. Furthermore, many opportunities exist to incorporate other protein-based motifs and inorganic materials into recombinant protein-based materials, extending the range and usefulness of these materials in potential biomedical applications. Elastin-like polypeptides (ELPs) can be assembled into 3-D architectures with precise control over payload encapsulation, mechanical and thermal properties, as well as unique functionalization opportunities through both genetic and enzymatic means. An overview of current protein-based materials, their properties and uses in biomedicine will be provided, with a focus on the advantages of ELPs. Applications of these biomaterials as imaging and therapeutic delivery agents will be discussed. Finally, broader implications and future directions of these materials as diagnostic and therapeutic systems will be explored.

  18. Designing Protein-Based Biomaterials for Medical Applications

    PubMed Central

    Gagner, Jennifer E.; Kim, Wookhyun; Chaikof, Elliot L.

    2013-01-01

    Biomaterials produced by nature have been honed through billions of years, evolving exquisitely precise structure-function relationships that scientists strive to emulate. Advances in genetic engineering have facilitated extensive investigations to determine how changes in even a single peptide within a protein sequence can produce biomaterials with unique thermal, mechanical and biological properties. Elastin, a naturally occurring protein polymer, serves as a model protein to determine the relationship between specific structural elements and desirable material characteristics. The modular, repetitive nature of the protein facilitates the formation of well-defined secondary structures with the ability to self-assemble into complex three-dimensional architectures on a variety of length scales. Furthermore, many opportunities exist to incorporate other protein-based motifs and inorganic materials into recombinant protein-based materials, extending the range and usefulness of these materials in potential biomedical applications. Elastin-like polypeptides can be assembled into 3D architectures with precise control over payload encapsulation, mechanical and thermal properties, as well as unique functionalization opportunities through both genetic and enzymatic means. An overview of current protein-based materials, their properties and uses in biomedicine will be provided, with a focus on the advantages of elastin-like polypeptides. Applications of these biomaterials as imaging and therapeutic delivery agents will be discussed. Finally, broader implications and future directions of these materials as diagnostic and therapeutic systems will be explored. PMID:24121196

  19. An Efficient Cloud Computing-Based Architecture for Freight System Application in China Railway

    NASA Astrophysics Data System (ADS)

    Zhang, Baopeng; Zhang, Ning; Li, Honghui; Liu, Feng; Miao, Kai

    Cloud computing is a new network computing paradigm of distributed application environment. It utilizes the computing resource and storage resource to dynamically provide on-demand service for users. The distribution and parallel characters of cloud computing can leverage the railway freight system. We implement a cloud computing-based architecture for freight system application, which explores the Tashi and Hadoop for virtual resource management and MapReduce-based search technology. We propose the semantic model and setup configuration parameter by experiment, and develop the prototype system for freight search and tracking.

  20. A proposed architecture for a satellite-based mobile communications network - The lowest three layers

    NASA Technical Reports Server (NTRS)

    Yan, T. Y.; Naderi, F. M.

    1986-01-01

    Architecture for a commercial mobile satellite network is proposed. The mobile satellite system (MSS) is composed of a network management center, mobile terminals, base stations, and gateways; the functions of each component are described. The satellite is a 'bent pipe' that performs frequency translations, and it has multiple UHF beams. The development of the MSS design based on the seven-layer open system interconnection model is examined. Consideration is given to the functions of the physical, data link, and network layers and the integrated adaptive mobile access protocol.

  1. Implementation methods of medical image sharing for collaborative health care based on IHE XDS-I profile

    PubMed Central

    Zhang, Jianguo; Zhang, Kai; Yang, Yuanyuan; Sun, Jianyong; Ling, Tonghui; Wang, Mingqing; Bak, Peter

    2015-01-01

    Abstract. IHE XDS-I profile proposes an architecture model for cross-enterprise medical image sharing, but there are only a few clinical implementations reported. Here, we investigate three pilot studies based on the IHE XDS-I profile to see whether we can use this architecture as a foundation for image sharing solutions in a variety of health-care settings. The first pilot study was image sharing for cross-enterprise health care with federated integration, which was implemented in Huadong Hospital and Shanghai Sixth People’s Hospital within the Shanghai Shen-Kang Hospital Management Center; the second pilot study was XDS-I–based patient-controlled image sharing solution, which was implemented by the Radiological Society of North America (RSNA) team in the USA; and the third pilot study was collaborative imaging diagnosis with electronic health-care record integration in regional health care, which was implemented in two districts in Shanghai. In order to support these pilot studies, we designed and developed new image access methods, components, and data models such as RAD-69/WADO hybrid image retrieval, RSNA clearinghouse, and extension of metadata definitions in both the submission set and the cross-enterprise document sharing (XDS) registry. We identified several key issues that impact the implementation of XDS-I in practical applications, and conclude that the IHE XDS-I profile is a theoretically good architecture and a useful foundation for medical image sharing solutions across multiple regional health-care providers. PMID:26835497

  2. Three-Dimensional Medical Image Analysis Using Local Dynamic Algorithm Selection on a Multiple-Instruction, Multiple-Data Architecture

    DTIC Science & Technology

    1989-01-01

    J. and Brown, Susan E. SPECT Single-Photon Emission Computed Tomography: A Primer. New York, New York: The Society of Nuclear Medicine, 1986. [Eri84...Rigid Objects," Computer Graphics, vol. 17, no. 3, pp. 65-69, July 1983. 457 [Fuc85] Fuchs, Henry; Goldfeather, Jack; Hultquist, Jeff P.; Spach, Susan ...Hay87] Hayes, John P.; Mudge, Trevor N.; Stout, Quentin F.; Colley Stephen; and Palmer, John. "Architecture of a Hypercube Supercomputer," Hypercube

  3. Architecture effects on multivalent interactions by polypeptide-based multivalent ligands

    NASA Astrophysics Data System (ADS)

    Liu, Shuang

    Multivalent interactions are characterized by the simultaneous binding between multiple ligands and multiple binding sites, either in solutions or at interfaces. In biological systems, most multivalent interactions occur between protein receptors and carbohydrate ligands through hydrogen-bonding and hydrophobic interactions. Compared with weak affinity binding between one ligand and one binding site, i.e. monovalent interaction, multivalent interactioins provide greater avidity and specificity, and therefore play unique roles in a broad range of biological activities. Moreover, the studies of multivalent interactions are also essential for producing effective inhibitors and effectors of biological processes that could have important therapeutic applications. Synthetic multivalent ligands have been designed to mimic the biological functions of natural multivalent interactions, and various types of scaffolds have been used to display multiple ligands, including small molecules, linear polymers, dendrimers, nanoparticle surfaces, monolayer surfaces and liposomes. Studies have shown that multivalent interactions can be highly affected by various architectural parameters of these multivalent ligands, including ligand identities, valencies, spacing, ligand densities, nature of linker arms, scaffold length and scaffold conformation. Most of these multivalent ligands are chemically synthesized and have limitations of controlling over sequence and conformation, which is a barrier for mimicking ordered and controlled natural biological systems. Therefore, multivalent ligands with precisely controlled architecture are required for improved structure-function relationship studies. Protein engineering methods with subsequent chemical coupling of ligands provide significant advantages of controlling over backbone conformation and functional group placement, and therefore have been used to synthesize recombinant protein-based materials with desired properties similar to natural

  4. [Evidence based medicine. A new paradigm for medical practice].

    PubMed

    Carneiro, A V

    1998-01-01

    Modern medical practice is an ever-changing process, and the doctor's need for information has been partially met by continuous medical education (CME) activities. It has been shown that CME activities have not prevented clinical knowledge, as well as medical practice, from deteriorating with time. When faced with the need to get the most recent and relevant information possible, the busy clinician has two major problems: most of the published medical literature is either irrelevant or not useful; and there is little time to read it. Evidence-based medicine constitutes a new paradigm for medical practice in the sense that it tries to transform clinical problems into well formulated clinical questions, selecting and critically appraising scientific evidence with predefined and rigorous rules. It combines the expertise of the individual clinician with the best external evidence from clinical research for rational, ethical and efficacious practice. Evidence-based medicine can be taught and practiced by physicians with different degrees of autonomy, with several subspecialties, working in the hospital or in outpatient clinics, alone or in groups.

  5. Medical education practice-based research networks: Facilitating collaborative research

    PubMed Central

    Schwartz, Alan; Young, Robin; Hicks, Patricia J.; APPD LEARN, For

    2016-01-01

    Abstract Background: Research networks formalize and institutionalize multi-site collaborations by establishing an infrastructure that enables network members to participate in research, propose new studies, and exploit study data to move the field forward. Although practice-based clinical research networks are now widespread, medical education research networks are rapidly emerging. Aims: In this article, we offer a definition of the medical education practice-based research network, a brief description of networks in existence in July 2014 and their features, and a more detailed case study of the emergence and early growth of one such network, the Association of Pediatric Program Directors Longitudinal Educational Assessment Research Network (APPD LEARN). Methods: We searched for extant networks through peer-reviewed literature and the world-wide web. Results: We identified 15 research networks in medical education founded since 2002 with membership ranging from 8 to 120 programs. Most focus on graduate medical education in primary care or emergency medicine specialties. Conclusions: We offer four recommendations for the further development and spread of medical education research networks: increasing faculty development, obtaining central resources, studying networks themselves, and developing networks of networks. PMID:25319404

  6. Content-based retrieval of medical images with relative entropy

    NASA Astrophysics Data System (ADS)

    Moshfeghi, Mehran; Saiz, Craig; Yu, Hua

    2004-04-01

    Medical image databases are growing at a rapid rate because of the increase in digital medical imaging modalities and the deployment of Picture Archiving and Communication Systems (PACS), Electronic Medical Records (EMR) and telemedicine applications. There is growing research interest in Content-Based Image Retrieval (CBIR) of medical images from such digital archives. A new distance function for CBIR is presented for measuring the similarity between two images. The distance function is a variant of relative entropy, or the Kullback-Liebler distance. The new distance is the sum of the relative entropy of the two images to each other. The latter is a symmetric non-negative function and is only zero when the two images have identical probability distributions. This method has been implemented in a prototype system and has been applied to a database of medical images. Initial results demonstrate improvements over L1-norm and L2-norm histogram matching. The method is computationally simple since it does not require image segmentation. It is invariant to translation, rotation and scaling. The method has also been extended to support retrieval based on Region-Of-Interest (ROI) queries.

  7. Efficient Graph Based Assembly of Short-Read Sequences on Hybrid Core Architecture

    SciTech Connect

    Sczyrba, Alex; Pratap, Abhishek; Canon, Shane; Han, James; Copeland, Alex; Wang, Zhong; Brewer, Tony; Soper, David; D'Jamoos, Mike; Collins, Kirby; Vacek, George

    2011-03-22

    Advanced architectures can deliver dramatically increased throughput for genomics and proteomics applications, reducing time-to-completion in some cases from days to minutes. One such architecture, hybrid-core computing, marries a traditional x86 environment with a reconfigurable coprocessor, based on field programmable gate array (FPGA) technology. In addition to higher throughput, increased performance can fundamentally improve research quality by allowing more accurate, previously impractical approaches. We will discuss the approach used by Convey?s de Bruijn graph constructor for short-read, de-novo assembly. Bioinformatics applications that have random access patterns to large memory spaces, such as graph-based algorithms, experience memory performance limitations on cache-based x86 servers. Convey?s highly parallel memory subsystem allows application-specific logic to simultaneously access 8192 individual words in memory, significantly increasing effective memory bandwidth over cache-based memory systems. Many algorithms, such as Velvet and other de Bruijn graph based, short-read, de-novo assemblers, can greatly benefit from this type of memory architecture. Furthermore, small data type operations (four nucleotides can be represented in two bits) make more efficient use of logic gates than the data types dictated by conventional programming models.JGI is comparing the performance of Convey?s graph constructor and Velvet on both synthetic and real data. We will present preliminary results on memory usage and run time metrics for various data sets with different sizes, from small microbial and fungal genomes to very large cow rumen metagenome. For genomes with references we will also present assembly quality comparisons between the two assemblers.

  8. A High-Throughput, Adaptive FFT Architecture for FPGA-Based Space-Borne Data Processors

    NASA Technical Reports Server (NTRS)

    Nguyen, Kayla; Zheng, Jason; He, Yutao; Shah, Biren

    2010-01-01

    Historically, computationally-intensive data processing for space-borne instruments has heavily relied on ground-based computing resources. But with recent advances in functional densities of Field-Programmable Gate-Arrays (FPGAs), there has been an increasing desire to shift more processing on-board; therefore relaxing the downlink data bandwidth requirements. Fast Fourier Transforms (FFTs) are commonly used building blocks for data processing applications, with a growing need to increase the FFT block size. Many existing FFT architectures have mainly emphasized on low power consumption or resource usage; but as the block size of the FFT grows, the throughput is often compromised first. In addition to power and resource constraints, space-borne digital systems are also limited to a small set of space-qualified memory elements, which typically lag behind the commercially available counterparts in capacity and bandwidth. The bandwidth limitation of the external memory creates a bottleneck for a large, high-throughput FFT design with large block size. In this paper, we present the Multi-Pass Wide Kernel FFT (MPWK-FFT) architecture for a moderately large block size (32K) with considerations to power consumption and resource usage, as well as throughput. We will also show that the architecture can be easily adapted for different FFT block sizes with different throughput and power requirements. The result is completely contained within an FPGA without relying on external memories. Implementation results are summarized.

  9. Virtues-Based Advice for Beginning Medical Students

    ERIC Educational Resources Information Center

    Coverdale, John H.

    2007-01-01

    Objective: The goals of this article are to present a framework, based on John Gregory's (1724-1773) concept of professionalism, for advising beginning medical students about what is important to training and to the practice of medicine. Method: The author presents Gregory's concept of professionalism with an emphasis on the related virtues.…

  10. Task-based Learning (TBL) in Undergraduate Medical Education.

    ERIC Educational Resources Information Center

    Virjo, Irma; Holmberg-Marttila, Doris; Mattila, Kari

    2001-01-01

    Describes task-based learning (TBL), a study module for fourth-year medical students (n=85), and experiences with implementing it at the University of Tampere in Finland. Indicates that this method works and that it leads to learning. Students evaluate their skills connected with a general practitioner's work in health center hospitals as better…

  11. Emergency Medical Technician. Competency Based Education Curriculum. Student Material.

    ERIC Educational Resources Information Center

    Spotts, Sue Ann

    Beginning with an introductory handbook, this competency-based curriculum contains 13 modules for an 81-hour secondary- or postsecondary-level course for Emergency Medical Technician (EMT). Introductory materials include module component descriptions and information for administering an EMT training program, such as an instructor's schedule, list…

  12. Geant4-based Monte Carlo simulations on GPU for medical applications.

    PubMed

    Bert, Julien; Perez-Ponce, Hector; El Bitar, Ziad; Jan, Sébastien; Boursier, Yannick; Vintache, Damien; Bonissent, Alain; Morel, Christian; Brasse, David; Visvikis, Dimitris

    2013-08-21

    Monte Carlo simulation (MCS) plays a key role in medical applications, especially for emission tomography and radiotherapy. However MCS is also associated with long calculation times that prevent its use in routine clinical practice. Recently, graphics processing units (GPU) became in many domains a low cost alternative for the acquisition of high computational power. The objective of this work was to develop an efficient framework for the implementation of MCS on GPU architectures. Geant4 was chosen as the MCS engine given the large variety of physics processes available for targeting different medical imaging and radiotherapy applications. In addition, Geant4 is the MCS engine behind GATE which is actually the most popular medical applications' simulation platform. We propose the definition of a global strategy and associated structures for such a GPU based simulation implementation. Different photon and electron physics effects are resolved on the fly directly on GPU without any approximations with respect to Geant4. Validations have shown equivalence in the underlying photon and electron physics processes between the Geant4 and the GPU codes with a speedup factor of 80-90. More clinically realistic simulations in emission and transmission imaging led to acceleration factors of 400-800 respectively compared to corresponding GATE simulations.

  13. Effectiveness of Team-Based Learning in teaching Medical Genetics to Medical Undergraduates

    PubMed Central

    Ismail, Noor Akmal Shareela

    2016-01-01

    This study explores the experience of both learners and a teacher during a team-based learning (TBL) session. TBL involves active learning that allows medical students to utilise their visual, auditory, writing and kinetic learning styles in order to strengthen their knowledge and retain it for longer, which is important with regard to applying basic sciences in clinical settings. This pilot study explored the effectiveness of TBL in learning medical genetics, and its potential to replace conventional lectures. First-year medical students (n = 194) studying at Universiti Kebangsaan, Malaysia, during 2014/2015 were selected to participate in this study. The topic of ‘Mutation and Mutation Analysis’ was selected, and the principles of TBL were adhered to during the study. It was found that the students’ performance in a group readiness test was better than in individual readiness tests. The effectiveness of TBL was further shown in the examination, during which the marks obtained were tremendously improved. Collective commentaries from both the learners and the teacher recommended TBL as another useful tool in learning medical genetics. Implementation strategies should be advanced for the benefit of future learners and teachers. PMID:27547118

  14. Effectiveness of Team-Based Learning in teaching Medical Genetics to Medical Undergraduates.

    PubMed

    Ismail, Noor Akmal Shareela

    2016-03-01

    This study explores the experience of both learners and a teacher during a team-based learning (TBL) session. TBL involves active learning that allows medical students to utilise their visual, auditory, writing and kinetic learning styles in order to strengthen their knowledge and retain it for longer, which is important with regard to applying basic sciences in clinical settings. This pilot study explored the effectiveness of TBL in learning medical genetics, and its potential to replace conventional lectures. First-year medical students (n = 194) studying at Universiti Kebangsaan, Malaysia, during 2014/2015 were selected to participate in this study. The topic of 'Mutation and Mutation Analysis' was selected, and the principles of TBL were adhered to during the study. It was found that the students' performance in a group readiness test was better than in individual readiness tests. The effectiveness of TBL was further shown in the examination, during which the marks obtained were tremendously improved. Collective commentaries from both the learners and the teacher recommended TBL as another useful tool in learning medical genetics. Implementation strategies should be advanced for the benefit of future learners and teachers.

  15. Applying representational state transfer (REST) architecture to archetype-based electronic health record systems

    PubMed Central

    2013-01-01

    Background The openEHR project and the closely related ISO 13606 standard have defined structures supporting the content of Electronic Health Records (EHRs). However, there is not yet any finalized openEHR specification of a service interface to aid application developers in creating, accessing, and storing the EHR content. The aim of this paper is to explore how the Representational State Transfer (REST) architectural style can be used as a basis for a platform-independent, HTTP-based openEHR service interface. Associated benefits and tradeoffs of such a design are also explored. Results The main contribution is the formalization of the openEHR storage, retrieval, and version-handling semantics and related services into an implementable HTTP-based service interface. The modular design makes it possible to prototype, test, replicate, distribute, cache, and load-balance the system using ordinary web technology. Other contributions are approaches to query and retrieval of the EHR content that takes caching, logging, and distribution into account. Triggering on EHR change events is also explored. A final contribution is an open source openEHR implementation using the above-mentioned approaches to create LiU EEE, an educational EHR environment intended to help newcomers and developers experiment with and learn about the archetype-based EHR approach and enable rapid prototyping. Conclusions Using REST addressed many architectural concerns in a successful way, but an additional messaging component was needed to address some architectural aspects. Many of our approaches are likely of value to other archetype-based EHR implementations and may contribute to associated service model specifications. PMID:23656624

  16. Setting Standards for Medically-Based Running Analysis

    PubMed Central

    Vincent, Heather K.; Herman, Daniel C.; Lear-Barnes, Leslie; Barnes, Robert; Chen, Cong; Greenberg, Scott; Vincent, Kevin R.

    2015-01-01

    Setting standards for medically based running analyses is necessary to ensure that runners receive a high-quality service from practitioners. Medical and training history, physical and functional tests, and motion analysis of running at self-selected and faster speeds are key features of a comprehensive analysis. Self-reported history and movement symmetry are critical factors that require follow-up therapy or long-term management. Pain or injury is typically the result of a functional deficit above or below the site along the kinematic chain. PMID:25014394

  17. Profile-based Retrieval of Records in Medical Databases

    PubMed Central

    Kementsietsidis, Anastasios; Lim, Lipyeow; Wang, Min

    2009-01-01

    Ontologies establish relationships between different terms, yet their potential in querying has not yet been fully realized. In this paper, we study the problem of ontology-supported profile-based retrieval of medical records. We present an algorithm that provides two independent techniques (used in isolation or in unison) to address the shortcomings of existing keyword-based retrieval solutions, and provide an implementation and experiments to illustrate the merits of our approach. PMID:20351871

  18. A model for critiquing based on automated medical records.

    PubMed

    van der Lei, J; Musen, M A

    1991-08-01

    We describe the design of a critiquing system, HyperCritic, that relies on automated medical records for its data input. The purpose of the system is to advise general practitioners who are treating patients who have hypertension. HyperCritic has access to the data stored in a primary-care information system that supports a fully automated medical record. Hyper-Critic relies on data in the automated medical record to critique the management of hypertensive patients, avoiding a consultation-style interaction with the user. The first step in the critiquing process involves the interpretation of the medical record in an attempt to discover the physician's actions and decisions. After detecting the relevant events in the medical record, HyperCritic views the task of critiquing as the assignment of critiquing statements to these patient-specific events. Critiquing statements are defined as recommendations involving one or more suggestions for possible modifications in the actions of the physician. The core of the model underlying HyperCritic is that the process of generating the critiquing statements is viewed as the application of a limited set of abstract critiquing tasks. We distinguish four categories of critiquing tasks: preparation tasks, selection tasks, monitoring tasks, and responding tasks. The execution of these critiquing tasks requires specific medical factual knowledge. This factual knowledge is separated from the critiquing tasks and is stored in a medical fact base. The principal advantage demonstrated by HyperCritic is the adaption of a domain-independent critiquing structure. We show how this domain-independent critiquing structure can be used to facilitate knowledge acquisition and maintenance of the system.

  19. Medical image segmentation based on SLIC superpixels model

    NASA Astrophysics Data System (ADS)

    Chen, Xiang-ting; Zhang, Fan; Zhang, Ruo-ya

    2017-01-01

    Medical imaging has been widely used in clinical practice. It is an important basis for medical experts to diagnose the disease. However, medical images have many unstable factors such as complex imaging mechanism, the target displacement will cause constructed defect and the partial volume effect will lead to error and equipment wear, which increases the complexity of subsequent image processing greatly. The segmentation algorithm which based on SLIC (Simple Linear Iterative Clustering, SLIC) superpixels is used to eliminate the influence of constructed defect and noise by means of the feature similarity in the preprocessing stage. At the same time, excellent clustering effect can reduce the complexity of the algorithm extremely, which provides an effective basis for the rapid diagnosis of experts.

  20. Frame semantics-based study of verbs across medical genres.

    PubMed

    Wandji Tchami, Ornella; L'Homme, Marie-Claude; Grabar, Natalia

    2014-01-01

    The field of medicine gathers actors with different levels of expertise. These actors must interact, although their mutual understanding is not always completely successful. We propose to study corpora (with high and low levels of expertise) in order to observe their specificities. More specifically, we perform a contrastive analysis of verbs, and of the syntactic and semantic features of their participants, based on the Frame Semantics framework and the methodology implemented in FrameNet. In order to achieve this, we use an existing medical terminology to automatically annotate the semantics classes of participants of verbs, which we assume are indicative of semantics roles. Our results indicate that verbs show similar or very close semantics in some contexts, while in other contexts they behave differently. These results are important for studying the understanding of medical information by patients and for improving the communication between patients and medical doctors.

  1. CRFs based de-identification of medical records

    PubMed Central

    He, Bin; Guan, Yi; Cheng, Jianyi; Cen, Keting; Hua, Wenlan

    2016-01-01

    De-identification is a shared task of the 2014 i2b2/UTHealth challenge. The purpose of this task is to remove protected health information (PHI) from medical records. In this paper, we propose a novel de-identifier, WI-deId, based on conditional random fields (CRFs). A preprocessing module, which tokenizes the medical records using regular expressions and an off-the-shelf tokenizer, is introduced, and three groups of features are extracted to train the de-identifier model. The experiment shows that our system is effective in the de-identification of medical records, achieving a micro-F1 of 0.9232 at the i2b2 strict entity evaluation level. PMID:26315662

  2. A Hierarchical Control Architecture for a PEBB-Based ILC Marx Modulator

    SciTech Connect

    Macken, K.; Burkhart, C.; Larsen, R.; Nguyen, M.N.; Olsen, J.; /SLAC

    2011-12-15

    The idea of building power conversion systems around Power Electronic Building Blocks (PEBBs) was initiated by the U.S. Office of Naval Research in the mid 1990s. A PEBB-based design approach is advantageous in terms of power density, modularity, reliability, and serviceability. It is obvious that this approach has much appeal for pulsed power conversion including the International Linear Collider (ILC) klystron modulator application. A hierarchical control architecture has the inherent capability to support the integration of PEBBs. This has already been successfully demonstrated in a number of industrial applications in the recent past. This paper outlines the underlying concepts of a hierarchical control architecture for a PEBB-based Marx-topology ILC klystron modulator. The control in PEBB-based power conversion systems can be functionally partitioned into (three) hierarchical layers; system layer, application layer, and PEBB layer. This has been adopted here. Based on such a hierarchical partition, the interfaces are clearly identified and defined and, consequently, are easily characterised. A conceptual design of the hardware manager, executing low-level hardware oriented tasks, is detailed. In addition, the idea of prognostics is briefly discussed.

  3. A UML-based ontology for describing hospital information system architectures.

    PubMed

    Winter, A; Brigl, B; Wendt, T

    2001-01-01

    To control the heterogeneity inherent to hospital information systems the information management needs appropriate hospital information systems modeling methods or techniques. This paper shows that, for several reasons, available modeling approaches are not able to answer relevant questions of information management. To overcome this major deficiency we offer an UML-based ontology for describing hospital information systems architectures. This ontology views at three layers: the domain layer, the logical tool layer, and the physical tool layer, and defines the relevant components. The relations between these components, especially between components of different layers make the answering of our information management questions possible.

  4. Orion Flight Test 1 Architecture: Observed Benefits of a Model Based Engineering Approach

    NASA Technical Reports Server (NTRS)

    Simpson, Kimberly A.; Sindiy, Oleg V.; McVittie, Thomas I.

    2012-01-01

    This paper details how a NASA-led team is using a model-based systems engineering approach to capture, analyze and communicate the end-to-end information system architecture supporting the first unmanned orbital flight of the Orion Multi-Purpose Crew Exploration Vehicle. Along with a brief overview of the approach and its products, the paper focuses on the observed program-level benefits, challenges, and lessons learned; all of which may be applied to improve system engineering tasks for characteristically similarly challenges

  5. Architecture optimization of nanobridge-based field-programmable gate array and its evaluation

    NASA Astrophysics Data System (ADS)

    Bai, Xu; Sakamoto, Toshitsugu; Tsuji, Yukihide; Miyamura, Makoto; Morioka, Ayuka; Nebashi, Ryusuke; Tada, Munehiro; Banno, Naoki; Okamoto, Koichiro; Iguchi, Noriyuki; Hada, Hiromitsu; Sugibayashi, Tadahiko

    2017-04-01

    Logic cell architecture on nanobridge-based field-programmable gate array (NB-FPGA) is investigated in terms of cell area and signal delay. Area-delay product is minimized when the cluster size is 4 and the segment length is 4, because of small area and small capacitance of nanobridge (NB). 1.34× logic density improvement and 15% energy saving, compared to the previous NB-FPGA with cluster size = 2, are demonstrated by implementing an application of a lightweight block cipher.

  6. Physics-based deformable organisms for medical image analysis

    NASA Astrophysics Data System (ADS)

    Hamarneh, Ghassan; McIntosh, Chris

    2005-04-01

    Previously, "Deformable organisms" were introduced as a novel paradigm for medical image analysis that uses artificial life modelling concepts. Deformable organisms were designed to complement the classical bottom-up deformable models methodologies (geometrical and physical layers), with top-down intelligent deformation control mechanisms (behavioral and cognitive layers). However, a true physical layer was absent and in order to complete medical image segmentation tasks, deformable organisms relied on pure geometry-based shape deformations guided by sensory data, prior structural knowledge, and expert-generated schedules of behaviors. In this paper we introduce the use of physics-based shape deformations within the deformable organisms framework yielding additional robustness by allowing intuitive real-time user guidance and interaction when necessary. We present the results of applying our physics-based deformable organisms, with an underlying dynamic spring-mass mesh model, to segmenting and labelling the corpus callosum in 2D midsagittal magnetic resonance images.

  7. Impact of PharmaNet-Based Admission Medication Reconciliation on Best Possible Medication Histories for Warfarin

    PubMed Central

    Au, Debbie; Wu, Hilary; San, Cindy; Chua, Doson; Su, Victoria; Kirkwood, Allison

    2016-01-01

    Background Inaccurate documentation of medication histories may lead to medication discrepancies during hospital admissions. Obtaining a best possible medication history (BPMH) for warfarin can be challenging because of frequent dosage changes and nonspecific directions of use (e.g., “take as directed”). On February 27, 2012, the study hospital implemented an admission medication reconciliation (MedRec) process using a form that compiled the most recent 6 months of outpatient prescription dispensing history from a provincial electronic database called PharmaNet. It was unclear whether admission MedRec had improved the process of obtaining warfarin BPMHs and the quality of their documentation. Objective To compare the rates of complete warfarin BPMH documentation before and after implementation of PharmaNet-based admission MedRec. Methods A single-centre, retrospective chart review was conducted using the health records of patients receiving warfarin who were admitted to the hospital’s Internal Medicine service before and after implementation of admission MedRec. The study periods were October 1, 2009, to February 26, 2012, and February 27, 2012, to July 31, 2014, respectively. The primary outcome was the rate of complete warfarin BPMH documentation during each period. Results Data were recorded for 100 patients in the pre-implementation phase and 100 patients in the post-implementation phase. The rates of complete warfarin BPMH documentation were 65% and 84% in these 2 phases, respectively (p = 0.002). Conclusion Implementation of PharmaNet-based admission MedRec was associated with a statistically significant increase in the rate of complete warfarin BPMH documentation. PMID:27826152

  8. Readout architecture based on the use of Silicon PhotoMultiplier (SiPM, or MMPC)

    NASA Astrophysics Data System (ADS)

    Marteau, J.; Carlus, B.; Gardien, S.; Girerd, C.; Ianigro, J.-C.; Montorio, J.-L.; Gibert, D.; Nicollin, F.

    2012-04-01

    The DIAPHANE project is pluri-disciplinary collaboration between particle physicists and geophysicists to perform the tomography of large geological structure mainly devoted to the study of active volcanoes. The detector used for this tomography, hereafter referred to as telescope, uses a standard, robust, cost-effective and well-known technology based on solid plastic scintillator readout by photomultiplier(s). The first generation of those telescopes, presently running in the Mont-Terri underground laboratory (St-Ursanne, Switzerland) and on the active volcano of La Soufrière (Guadeloupe, Lesser Antilles, France), uses Hamamatsu H8804-200mod photomultipliers. We present an upgrade of the readout architecture based on the use of Silicon PhotoMultiplier (SiPM, or MMPC) which allows to simplify the optical connections w.r.t. the present design and to benefit from the high photo-dectection efficiency of the SiPM. To ensure an effective increase in the muon detection efficiency one has to optimize the first trigger level and find the best compromise between photostatistics and the tails of the dark noise contributions. Several readout architectures, based or not on dedicated ASICs, are discussed and compared in this article.

  9. Cool Apps: Building Cryospheric Data Applications With Standards-Based Service Oriented Architecture

    NASA Astrophysics Data System (ADS)

    Collins, J. A.; Truslove, I.; Billingsley, B. W.; Oldenburg, J.; Brodzik, M.; Lewis, S.; Liu, M.

    2012-12-01

    The National Snow and Ice Data Center (NSIDC) holds a large collection of cryospheric data, and is involved in a number of informatics research and development projects aimed at improving the discoverability and accessibility of these data. To develop high-quality software in a timely manner, we have adopted a Service-Oriented Architecture (SOA) approach for our core technical infrastructure development. Data services at NSIDC are internally exposed to other tools and applications through standards-based service interfaces. These standards include OAI-PMH (Open Archives Initiative Protocol for Metadata Harvesting), various OGC (Open Geospatial Consortium) standards including WMS (Web Map Service) and WFS (Web Feature Service), ESIP (Federation of Earth Sciences Information Partners) OpenSearch, and NSIDC-specific RESTful services. By taking a standards-based approach, we are able to use off-the-shelf tools and libraries to consume, translate and broker these data services, and thus develop applications faster. Additionally, by exposing public interfaces to these services we provide valuable data services to technical collaborators; for example, NASA Reverb (http://reverb.echo.nasa.gov) uses NSIDC's WMS services. Our latest generation of web applications consume these data services directly. The most complete example of this is the Operation IceBridge Data Portal (http://nsidc.org/icebridge/portal) which depends on many of the aforementioned services, and clearly exhibits many of the advantages of building applications atop a service-oriented architecture. This presentation outlines the architectural approach and components and open standards and protocols adopted at NSIDC, demonstrates the interactions and uses of public and internal service interfaces currently powering applications including the IceBridge Data Portal, and outlines the benefits and challenges of this approach.

  10. Geriatrics in medical students’ curricula: questionnaire-based analysis

    PubMed Central

    2014-01-01

    Background Demographic development is accompanied by an increasingly aging society. Concerning medical education, the treatment of older people as well as the scientific research and exploration of ageing aspects in the coming years need to be considered. Aim of the study was to ascertain medical students’ knowledge, interest, and attitudes regarding older patients and geriatric medicine. Methods Each participant completed a self-designed questionnaire. This questionnaire was based on three validated internationally recognised questionnaires (“Facts on Aging Quiz – FAQ”, “Expectations Regarding Aging – ERA” and the “Aging Semantic Differential – ASD”). The inquiry and survey were performed at the beginning of the summer term in 2012 at the University of Regensburg Medical School. Results A total of n = 184/253 (72.7%) students participated in this survey. The results of the FAQ 25+ showed that respondents were able to answer an average of M = 20.4 of 36 questions (56.7%) correctly (Median, Md = 21; SD ±6.1). The personal attitudes and expectations of ageing averaged M = 41.2 points on the Likert-scale that ranged from 0 to 100 (Md = 40.4; SD ±13.7). Respondents’ attitudes towards the elderly (ASD 24) averaged M = 3.5 points on the Likert-scale (range 1–7, Md 3.6, SD ±0.8). Conclusions In our investigation, medical students’ knowledge of ageing was comparable to previous surveys. Attitudes and expectations of ageing were more positive compared to previous studies. Overall, medical students expect markedly high cognitive capacities towards older people that can actively prevent cognitive impairment. However, medical students’ personal interest in medicine of ageing and older people seems to be rather slight. PMID:25062568

  11. Problem-based learning in continuing medical education

    PubMed Central

    Al-Azri, Hilal; Ratnapalan, Savithiri

    2014-01-01

    Abstract Objective To investigate the effects of problem-based learning (PBL) in continuing medical education. Data sources PubMed, MEDLINE, EMBASE, CINAHL, and ERIC databases were searched for randomized controlled trials published in English from January 2001 to May 2011 using key words problem-based learning, practice-based, self-directed, learner-centered, and active learning, combined with continuing medical education, continuing professional development, post professional, postgraduate, and adult learning. Study selection Randomized controlled trials that described the effects of PBL on knowledge enhancement, performance improvement, participants’ satisfaction, or patients’ health outcomes were selected for analysis. Synthesis Fifteen studies were included in this review: 4 involved postgraduate trainee doctors, 10 involved practising physicians, and 1 had both groups. Online learning was used in 7 studies. Among postgraduate trainees PBL showed no significant differences in knowledge gain compared with lectures or non–case-based learning. In continuing education, PBL showed no significant difference in knowledge gain when compared with other methods. Several studies did not provide an educational intervention for the control group. Physician performance improvement showed an upward trend in groups participating in PBL, but no significant differences were noted in health outcomes. Conclusion Online PBL is a useful method of delivering continuing medical education. There is limited evidence that PBL in continuing education would enhance physicians’ performance or improve health outcomes. PMID:24522680

  12. Box Architecture.

    ERIC Educational Resources Information Center

    Ham, Jan

    1998-01-01

    Project offers grades 3-8 students hands-on design practice creating built environments to solve a society-based architectural problem. Students plan buildings, draw floor plans, and make scale models of the structures that are then used in related interdisciplinary activities. (Author)

  13. Intention-based critiquing of guideline-oriented medical care.

    PubMed

    Advani, A; Lo, K; Shahar, Y

    1998-01-01

    We present a methodology and tool for providing retrospective review and critiquing of guideline-based medical care given to patients. We show how our guideline representation language, Asbru, which supports the use of physicians intentions in addition to physician's actions, allows us to compare the care given to a patient at the level of the intention to treat in addition to the more detailed plan carried out. We have developed an algorithm based on this representation for retrospective quality assessment of guideline-based care. Our method takes the physician's and institution's preferences and policies into account in explaining or justifying physician deviations from the recommendations of a guideline.

  14. Model-Based Engine Control Architecture with an Extended Kalman Filter

    NASA Technical Reports Server (NTRS)

    Csank, Jeffrey T.; Connolly, Joseph W.

    2016-01-01

    This paper discusses the design and implementation of an extended Kalman filter (EKF) for model-based engine control (MBEC). Previously proposed MBEC architectures feature an optimal tuner Kalman Filter (OTKF) to produce estimates of both unmeasured engine parameters and estimates for the health of the engine. The success of this approach relies on the accuracy of the linear model and the ability of the optimal tuner to update its tuner estimates based on only a few sensors. Advances in computer processing are making it possible to replace the piece-wise linear model, developed off-line, with an on-board nonlinear model running in real-time. This will reduce the estimation errors associated with the linearization process, and is typically referred to as an extended Kalman filter. The nonlinear extended Kalman filter approach is applied to the Commercial Modular Aero-Propulsion System Simulation 40,000 (C-MAPSS40k) and compared to the previously proposed MBEC architecture. The results show that the EKF reduces the estimation error, especially during transient operation.

  15. Model-Based Engine Control Architecture with an Extended Kalman Filter

    NASA Technical Reports Server (NTRS)

    Csank, Jeffrey T.; Connolly, Joseph W.

    2016-01-01

    This paper discusses the design and implementation of an extended Kalman filter (EKF) for model-based engine control (MBEC). Previously proposed MBEC architectures feature an optimal tuner Kalman Filter (OTKF) to produce estimates of both unmeasured engine parameters and estimates for the health of the engine. The success of this approach relies on the accuracy of the linear model and the ability of the optimal tuner to update its tuner estimates based on only a few sensors. Advances in computer processing are making it possible to replace the piece-wise linear model, developed off-line, with an on-board nonlinear model running in real-time. This will reduce the estimation errors associated with the linearization process, and is typically referred to as an extended Kalman filter. The non-linear extended Kalman filter approach is applied to the Commercial Modular Aero-Propulsion System Simulation 40,000 (C-MAPSS40k) and compared to the previously proposed MBEC architecture. The results show that the EKF reduces the estimation error, especially during transient operation.

  16. Evaluation of Cache-based Superscalar and Cacheless Vector Architectures for Scientific Computations

    NASA Technical Reports Server (NTRS)

    Oliker, Leonid; Carter, Jonathan; Shalf, John; Skinner, David; Ethier, Stephane; Biswas, Rupak; Djomehri, Jahed; VanderWijngaart, Rob

    2003-01-01

    The growing gap between sustained and peak performance for scientific applications has become a well-known problem in high performance computing. The recent development of parallel vector systems offers the potential to bridge this gap for a significant number of computational science codes and deliver a substantial increase in computing capabilities. This paper examines the intranode performance of the NEC SX6 vector processor and the cache-based IBM Power3/4 superscalar architectures across a number of key scientific computing areas. First, we present the performance of a microbenchmark suite that examines a full spectrum of low-level machine characteristics. Next, we study the behavior of the NAS Parallel Benchmarks using some simple optimizations. Finally, we evaluate the perfor- mance of several numerical codes from key scientific computing domains. Overall results demonstrate that the SX6 achieves high performance on a large fraction of our application suite and in many cases significantly outperforms the RISC-based architectures. However, certain classes of applications are not easily amenable to vectorization and would likely require extensive reengineering of both algorithm and implementation to utilize the SX6 effectively.

  17. Photosensitive-polyimide based method for fabricating various neural electrode architectures.

    PubMed

    Kato, Yasuhiro X; Furukawa, Shigeto; Samejima, Kazuyuki; Hironaka, Naoyuki; Kashino, Makio

    2012-01-01

    An extensive photosensitive-polyimide (PSPI)-based method for designing and fabricating various neural electrode architectures was developed. The method aims to broaden the design flexibility and expand the fabrication capability for neural electrodes to improve the quality of recorded signals and integrate other functions. After characterizing PSPI's properties for micromachining processes, we successfully designed and fabricated various neural electrodes even on a non-flat substrate using only one PSPI as an insulation material and without the time-consuming dry etching processes. The fabricated neural electrodes were an electrocorticogram (ECoG) electrode, a mesh intracortical electrode with a unique lattice-like mesh structure to fixate neural tissue, and a guide cannula electrode with recording microelectrodes placed on the curved surface of a guide cannula as a microdialysis probe. In vivo neural recordings using anesthetized rats demonstrated that these electrodes can be used to record neural activities repeatedly without any breakage and mechanical failures, which potentially promises stable recordings for long periods of time. These successes make us believe that this PSPI-based fabrication is a powerful method, permitting flexible design, and easy optimization of electrode architectures for a variety of electrophysiological experimental research with improved neural recording performance.

  18. The Emergence of Agent-Based Technology as an Architectural Component of Serious Games

    NASA Technical Reports Server (NTRS)

    Phillips, Mark; Scolaro, Jackie; Scolaro, Daniel

    2010-01-01

    The evolution of games as an alternative to traditional simulations in the military context has been gathering momentum over the past five years, even though the exploration of their use in the serious sense has been ongoing since the mid-nineties. Much of the focus has been on the aesthetics of the visuals provided by the core game engine as well as the artistry provided by talented development teams to produce not only breathtaking artwork, but highly immersive game play. Consideration of game technology is now so much a part of the modeling and simulation landscape that it is becoming difficult to distinguish traditional simulation solutions from game-based approaches. But games have yet to provide the much needed interactive free play that has been the domain of semi-autonomous forces (SAF). The component-based middleware architecture that game engines provide promises a great deal in terms of options for the integration of agent solutions to support the development of non-player characters that engage the human player without the deterministic nature of scripted behaviors. However, there are a number of hard-learned lessons on the modeling and simulation side of the equation that game developers have yet to learn, such as: correlation of heterogeneous systems, scalability of both terrain and numbers of non-player entities, and the bi-directional nature of simulation to game interaction provided by Distributed Interactive Simulation (DIS) and High Level Architecture (HLA).

  19. Evaluation of cache-based superscalar and cacheless vector architectures for scientific computations

    SciTech Connect

    Oliker, Leonid; Canning, Andrew; Carter, Jonathan; Shalf, John; Skinner, David; Ethier, Stephane; Biswas, Rupak; Djomehri, Jahed; Van der Wijngaart, Rob

    2003-05-01

    The growing gap between sustained and peak performance for scientific applications is a well-known problem in high end computing. The recent development of parallel vector systems offers the potential to bridge this gap for many computational science codes and deliver a substantial increase in computing capabilities. This paper examines the intranode performance of the NEC SX-6 vector processor and the cache-based IBM Power3/4 superscalar architectures across a number of scientific computing areas. First, we present the performance of a microbenchmark suite that examines low-level machine characteristics. Next, we study the behavior of the NAS Parallel Benchmarks. Finally, we evaluate the performance of several scientific computing codes. Results demonstrate that the SX-6 achieves high performance on a large fraction of our applications and often significantly out performs the cache-based architectures. However, certain applications are not easily amenable to vectorization and would re quire extensive algorithm and implementation reengineering to utilize the SX-6 effectively.

  20. An architecture for integrating distributed and cooperating knowledge-based Air Force decision aids

    NASA Technical Reports Server (NTRS)

    Nugent, Richard O.; Tucker, Richard W.

    1988-01-01

    MITRE has been developing a Knowledge-Based Battle Management Testbed for evaluating the viability of integrating independently-developed knowledge-based decision aids in the Air Force tactical domain. The primary goal for the testbed architecture is to permit a new system to be added to a testbed with little change to the system's software. Each system that connects to the testbed network declares that it can provide a number of services to other systems. When a system wants to use another system's service, it does not address the server system by name, but instead transmits a request to the testbed network asking for a particular service to be performed. A key component of the testbed architecture is a common database which uses a relational database management system (RDBMS). The RDBMS provides a database update notification service to requesting systems. Normally, each system is expected to monitor data relations of interest to it. Alternatively, a system may broadcast an announcement message to inform other systems that an event of potential interest has occurred. Current research is aimed at dealing with issues resulting from integration efforts, such as dealing with potential mismatches of each system's assumptions about the common database, decentralizing network control, and coordinating multiple agents.

  1. A top-down manner-based DCNN architecture for semantic image segmentation

    PubMed Central

    Qiao, Kai; Chen, Jian; Wang, Linyuan; Zeng, Lei

    2017-01-01

    Given their powerful feature representation for recognition, deep convolutional neural networks (DCNNs) have been driving rapid advances in high-level computer vision tasks. However, their performance in semantic image segmentation is still not satisfactory. Based on the analysis of visual mechanism, we conclude that DCNNs in a bottom-up manner are not enough, because semantic image segmentation task requires not only recognition but also visual attention capability. In the study, superpixels containing visual attention information are introduced in a top-down manner, and an extensible architecture is proposed to improve the segmentation results of current DCNN-based methods. We employ the current state-of-the-art fully convolutional network (FCN) and FCN with conditional random field (DeepLab-CRF) as baselines to validate our architecture. Experimental results of the PASCAL VOC segmentation task qualitatively show that coarse edges and error segmentation results are well improved. We also quantitatively obtain about 2%-3% intersection over union (IOU) accuracy improvement on the PASCAL VOC 2011 and 2012 test sets. PMID:28339486

  2. Historic Building Information Modelling - Adding intelligence to laser and image based surveys of European classical architecture

    NASA Astrophysics Data System (ADS)

    Murphy, Maurice; McGovern, Eugene; Pavia, Sara

    2013-02-01

    Historic Building Information Modelling (HBIM) is a novel prototype library of parametric objects, based on historic architectural data and a system of cross platform programmes for mapping parametric objects onto point cloud and image survey data. The HBIM process begins with remote collection of survey data using a terrestrial laser scanner combined with digital photo modelling. The next stage involves the design and construction of a parametric library of objects, which are based on the manuscripts ranging from Vitruvius to 18th century architectural pattern books. In building parametric objects, the problem of file format and exchange of data has been overcome within the BIM ArchiCAD software platform by using geometric descriptive language (GDL). The plotting of parametric objects onto the laser scan surveys as building components to create or form the entire building is the final stage in the reverse engineering process. The final HBIM product is the creation of full 3D models including detail behind the object's surface concerning its methods of construction and material make-up. The resultant HBIM can automatically create cut sections, details and schedules in addition to the orthographic projections and 3D models (wire frame or textured) for both the analysis and conservation of historic objects, structures and environments.

  3. Medical marijuana patient counseling points for health care professionals based on trends in the medical uses, efficacy, and adverse effects of cannabis-based pharmaceutical drugs.

    PubMed

    Parmar, Jayesh R; Forrest, Benjamin D; Freeman, Robert A

    2016-01-01

    The purpose of this report is to present a review of the medical uses, efficacy, and adverse effects of the three approved cannabis-based medications and ingested marijuana. A literature review was conducted utilizing key search terms: dronabinol, nabilone, nabiximols, cannabis, marijuana, smoke, efficacy, toxicity, cancer, multiple sclerosis, nausea, vomiting, appetite, pain, glaucoma, and side effects. Abstracts of the included literature were reviewed, analyzed, and organized to identify the strength of evidence in medical use, efficacy, and adverse effects of the approved cannabis-based medications and medical marijuana. A total of 68 abstracts were included for review. Dronabinol's (Marinol) most common medical uses include weight gain, chemotherapy-induced nausea and vomiting (CINV), and neuropathic pain. Nabiximol's (Sativex) most common medical uses include spasticity in multiple sclerosis (MS) and neuropathic pain. Nabilone's (Cesamet) most common medical uses include CINV and neuropathic pain. Smoked marijuana's most common medical uses include neuropathic pain and glaucoma. Orally ingested marijuana's most common medical uses include improving sleep, reducing neuropathic pain, and seizure control in MS. In general, all of these agents share similar medical uses. The reported adverse effects of the three cannabis-based medications and marijuana show a major trend in central nervous system (CNS)-related adverse effects along with cardiovascular and respiratory related adverse effects. Marijuana shares similar medical uses with the approved cannabis-based medications dronabinol (Marinol), nabiximols (Sativex), and nabilone (Cesamet), but the efficacy of marijuana for these medical uses has not been fully determined due to limited and conflicting literature. Medical marijuana also has similar adverse effects as the FDA-approved cannabis-based medications mainly consisting of CNS related adverse effects but also including cardiovascular and respiratory

  4. Mobile phone middleware architecture for energy and context awareness in location-based services.

    PubMed

    Galeana-Zapién, Hiram; Torres-Huitzil, César; Rubio-Loyola, Javier

    2014-12-10

    The disruptive innovation of smartphone technology has enabled the development of mobile sensing applications leveraged on specialized sensors embedded in the device. These novel mobile phone applications rely on advanced sensor information processes, which mainly involve raw data acquisition, feature extraction, data interpretation and transmission. However, the continuous accessing of sensing resources to acquire sensor data in smartphones is still very expensive in terms of energy, particularly due to the periodic use of power-intensive sensors, such as the Global Positioning System (GPS) receiver. The key underlying idea to design energy-efficient schemes is to control the duty cycle of the GPS receiver. However, adapting the sensing rate based on dynamic context changes through a flexible middleware has received little attention in the literature. In this paper, we propose a novel modular middleware architecture and runtime environment to directly interface with application programming interfaces (APIs) and embedded sensors in order to manage the duty cycle process based on energy and context aspects. The proposed solution has been implemented in the Android software stack. It allows continuous location tracking in a timely manner and in a transparent way to the user. It also enables the deployment of sensing policies to appropriately control the sampling rate based on both energy and perceived context. We validate the proposed solution taking into account a reference location-based service (LBS) architecture. A cloud-based storage service along with online mobility analysis tools have been used to store and access sensed data. Experimental measurements demonstrate the feasibility and efficiency of our middleware, in terms of energy and location resolution.

  5. Architecture and methods for UAV-based heterogeneous sensor network applications

    NASA Astrophysics Data System (ADS)

    Antonio, Pedro; Caputo, Davide; Gandelli, Alessandro; Grimaccia, Francesco; Mussetta, Marco

    2012-09-01

    Wireless sensor netwoks (WSN) employ miniaturized devices which integrate sensing, processing, and communication capabilities. In this paper an innovative mobile platform for heterogeneous sensor networks is presented, combined with adaptive methods to optimize the communication architecture for novel potential applications even in coastal and marine environment monitoring. In fact, in the near future, WSN data collection could be performed by UAV platforms which can be a sink for ground sensors layer, acting essentially as a mobile gateway. In order to maximize the system performances and the network lifespan, the authors propose a recently developed hybrid technique based on evolutionary algorithms. This procedure is here applied to optimize the communication energy consumption in WSN by selecting the optimal multi-hop routing schemes, with a suitable hybridization of different routing criteria. The proposed approach can be potentially extended and applied to ongoing research projects focused on UAV-based remote sensing of the ocean, sea ice, coastal waters, and large water regions.

  6. Experimental characterization of a new multicasting node architecture based on space splitters and wavelength converters

    NASA Astrophysics Data System (ADS)

    He, Hao; Su, Yikai; Hu, Peigang; Hu, Weisheng

    2005-11-01

    IPTV-based broadband services such as interactive multimedia and video conferencing are considered as promising revenue-adding services, and multicast is proven to be a good supplier to support these applications for its reduced consumption of network bandwidth. Generally there are two approaches to implement optical layer multicast. One is space-domain multicast using space-splitter which is low cost but has wavelength continuity constraint, the other is frequency-domain multicast using wavelength converter which resolves the wavelength continuity but with high costs. A new multicasting node which adopts both space-domain multicast and frequency-domain multicast is recently discussed. In this paper we present an experimental demonstration of the new multicasting node architecture based on space splitters and wavelength converters, measurements to characterize such a node are provided.

  7. Memory Size Reduction Technique of SDF IFFT Architecture for OFDM-Based Applications

    NASA Astrophysics Data System (ADS)

    Jang, In-Gul; Cho, Kyung-Ju; Kim, Yong-Eun; Chung, Jin-Gyun

    In this paper, to reduce the memory size requirements of IFFT for OFDM-based applications, we propose a new IFFT design technique based on a combined integer mapping of three IFFT input signals: modulated data, pilot and null signals. The proposed method focuses on reducing the size of memory cells in the first two stages of the single-path delay feedback (SDF) IFFT architectures since the first two stages require 75% of the total memory cells. By simulations of 2048-point IFFT design for cognitive radio systems, it is shown that the proposed IFFT design method achieves more than 13% reduction in gate count and 11% reduction in power consumption compared with conventional IFFT design.

  8. Managing medical and insurance information through a smart-card-based information system.

    PubMed

    Lambrinoudakis, C; Gritzalis, S

    2000-08-01

    The continuously increased mobility of patients and doctors, in conjunction with the existence of medical groups consisting of private doctors, general practitioners, hospitals, medical centers, and insurance companies, pose significant difficulties on the management of patients' medical data. Inevitably this affects the quality of the health care services provided. The evolving smart card technology can be utilized for the implementation of a secure portable electronic medical record, carried by the patient herself/himself. In addition to the medical data, insurance information can be stored in the smart card thus facilitating the creation of an "intelligent system" supporting the efficient management of patient's data. In this paper we present the main architectural and functional characteristics of such a system. We also highlight how the security features offered by smart cards can be exploited in order to ensure confidentiality and integrity of the medical data stored in the patient cards.

  9. A method of image multi-resolution processing based on FPGA + DSP architecture

    NASA Astrophysics Data System (ADS)

    Peng, Xiaohan; Zhong, Sheng; Lu, Hongqiang

    2015-10-01

    In real-time image processing, with the improvement of resolution and frame rate of camera imaging, not only the requirement of processing capacity is improving, but also the requirement of the optimization of process is improving. With regards to the FPGA + DSP architecture image processing system, there are three common methods to overcome the challenge above. The first is using higher performance DSP. For example, DSP with higher core frequency or with more cores can be used. The second is optimizing the processing method, make the algorithm to accomplish the same processing results but spend less time. Last but not least, pre-processing in the FPGA can make the image processing more efficient. A method of multi-resolution pre-processing by FPGA based on FPGA + DSP architecture is proposed here. It takes advantage of built-in first in first out (FIFO) and external synchronous dynamic random access memory (SDRAM) to buffer the images which come from image detector, and provides down-sampled images or cut-down images for DSP flexibly and efficiently according to the request parameters sent by DSP. DSP can thus get the degraded image instead of the whole image to process, shortening the processing time and transmission time greatly. The method results in alleviating the burden of image processing of DSP and also solving the problem of single method of image resolution reduction cannot meet the requirements of image processing task of DSP.

  10. Experimenting with an Evolving Ground/Space-based Software Architecture to Enable Sensor Webs

    NASA Technical Reports Server (NTRS)

    mandl, Daniel; Frye, Stuart

    2005-01-01

    A series of ongoing experiments are being conducted at the NASA Goddard Space Flight Center to explore integrated ground and space-based software architectures enabling sensor webs. A sensor web, as defined by Steve Talabac at NASA Goddard Space Flight Center(GSFC), is a coherent set of distributed nodes interconnected by a communications fabric, that collectively behave as a single, dynamically adaptive, observing system. The nodes can be comprised of satellites, ground instruments, computing nodes etc. Sensor web capability requires autonomous management of constellation resources. This becomes progressively more important as more and more satellites share resource, such as communication channels and ground station,s while automatically coordinating their activities. There have been five ongoing activities which include an effort to standardize a set of middleware. This paper will describe one set of activities using the Earth Observing 1 satellite, which used a variety of ground and flight software along with other satellites and ground sensors to prototype a sensor web. This activity allowed us to explore where the difficulties that occur in the assembly of sensor webs given today s technology. We will present an overview of the software system architecture, some key experiments and lessons learned to facilitate better sensor webs in the future.

  11. A single-board NMR spectrometer based on a software defined radio architecture

    NASA Astrophysics Data System (ADS)

    Tang, Weinan; Wang, Weimin

    2011-01-01

    A single-board software defined radio (SDR) spectrometer for nuclear magnetic resonance (NMR) is presented. The SDR-based architecture, realized by combining a single field programmable gate array (FPGA) and a digital signal processor (DSP) with peripheral radio frequency (RF) front-end circuits, makes the spectrometer compact and reconfigurable. The DSP, working as a pulse programmer, communicates with a personal computer via a USB interface and controls the FPGA through a parallel port. The FPGA accomplishes digital processing tasks such as a numerically controlled oscillator (NCO), digital down converter (DDC) and gradient waveform generator. The NCO, with agile control of phase, frequency and amplitude, is part of a direct digital synthesizer that is used to generate an RF pulse. The DDC performs quadrature demodulation, multistage low-pass filtering and gain adjustment to produce a bandpass signal (receiver bandwidth from 3.9 kHz to 10 MHz). The gradient waveform generator is capable of outputting shaped gradient pulse waveforms and supports eddy-current compensation. The spectrometer directly acquires an NMR signal up to 30 MHz in the case of baseband sampling and is suitable for low-field (<0.7 T) application. Due to the featured SDR architecture, this prototype has flexible add-on ability and is expected to be suitable for portable NMR systems.

  12. A terabit capacity passive polymer optical backplane based on a novel meshed waveguide architecture

    NASA Astrophysics Data System (ADS)

    Beals, J.; Bamiedakis, N.; Wonfor, A.; Penty, R. V.; White, I. H.; Degroot, J. V.; Hueston, K.; Clapp, T. V.; Glick, M.

    2009-06-01

    An optical backplane based on a meshed polymer waveguide architecture enabling high-speed board-to-board optical interconnection is presented. This planar array of multimode polymer waveguides can provide passive strictly non-blocking links between server line cards fitted with optical transmitter and receiver arrays. This architecture offers a scalable and low-cost solution to the bandwidth limitations faced by electrical backplanes and is suitable for PCB integration. The reported backplane demonstrator uses a matrix of 100 waveguides each capable of 10 Gb/s operation to interconnect 10 cards for a total capacity of a terabit per second aggregate data rate in multicast mode. Characterisation of the backplane demonstrator reveals low link losses of 2 to 8 dB for a multimode fibre input and crosstalk values below -35 dB. Error free data transmission at 10 Gb/s is achieved with a power penalty of only 0.2 dB at a bit-error-rate of 10-9. Additionally, lossless operation of a Gigabit Ethernet link over the backplane is achieved even when using the worst-case highest loss links.

  13. Phylogeny-based developmental analyses illuminate evolution of inflorescence architectures in dogwoods (Cornus s. l., Cornaceae).

    PubMed

    Feng, Chun-Miao; Xiang, Qiu-Yun Jenny; Franks, Robert G

    2011-08-01

    • Inflorescence architecture is important to angiosperm reproduction, but our knowledge of the developmental basis underlying the evolution of inflorescence architectures is limited. Using a phylogeny-based comparative analysis of developmental pathways, we tested the long-standing hypothesis that umbel evolved from elongated inflorescences by suppression of inflorescence branches, while head evolved from umbels by suppression of pedicels. • The developmental pathways of six species of Cornus producing different inflorescence types were characterized by scanning electron microscopy (SEM) and histological analysis. Critical developmental events were traced over the molecular phylogeny to identify evolutionary changes leading to the formation of umbels and heads using methods accounting for evolutionary time and phylogenetic uncertainty. • We defined 24 developmental events describing the developmental progression of the different inflorescence types. The evolutionary transition from paniculate cymes to umbels and heads required alterations of seven developmental events occurring at different evolutionary times. • Our results indicate that heads and umbels evolved independently in Cornus from elongated forms via an umbellate dichasium ancestor and this process involved several independent changes. Our findings shed novel insights into head and umbel evolution concealed by outer morphology. Our work illustrates the importance of combining developmental and phylogenetic data to better define morphological evolutionary processes.

  14. New FPSoC-based architecture for efficient FSBM motion estimation processing in video standards

    NASA Astrophysics Data System (ADS)

    Canals, J. A.; Martínez, M. A.; Ballester, F. J.; Mora, A.

    2007-05-01

    Due to the timing constraints in real time video encoding, hardware accelerator cores are used for video compression. System on Chip (SoC) designing tools offer a complex microprocessor system designing methodologies with an easy Intellectual Property (IP) core integration. This paper presents a PowerPC-based SoC with a motion-estimation accelerator core attached to the system bus. Motion-estimation (ME) algorithms are the most critical part in video compression due to the huge amount of data transfers and processing time. The main goal of our proposed architecture is to minimize the amount of memory accesses, thus exploiting the bandwidth of a direct memory connection. This architecture has been developed using Xilinx XPS, a SoC platforms design tool. The results show that our system is able to process the integer pixel full search block matching (FSBM) motion-estimation process and interframe mode decision of a QCIF frame (176*144 pixels), using a 48*48 pixel searching window, with an embedded PPC in a Xilinx Virtex-4 FPGA running at 100 MHz, in 1.5 ms, 4.5 % of the total processing time at 30 fps.

  15. Field-programmable lab-on-a-chip based on microelectrode dot array architecture.

    PubMed

    Wang, Gary; Teng, Daniel; Lai, Yi-Tse; Lu, Yi-Wen; Ho, Yingchieh; Lee, Chen-Yi

    2014-09-01

    The fundamentals of electrowetting-on-dielectric (EWOD) digital microfluidics are very strong: advantageous capability in the manipulation of fluids, small test volumes, precise dynamic control and detection, and microscale systems. These advantages are very important for future biochip developments, but the development of EWOD microfluidics has been hindered by the absence of: integrated detector technology, standard commercial components, on-chip sample preparation, standard manufacturing technology and end-to-end system integration. A field-programmable lab-on-a-chip (FPLOC) system based on microelectrode dot array (MEDA) architecture is presented in this research. The MEDA architecture proposes a standard EWOD microfluidic component called 'microelectrode cell', which can be dynamically configured into microfluidic components to perform microfluidic operations of the biochip. A proof-of-concept prototype FPLOC, containing a 30 × 30 MEDA, was developed by using generic integrated circuits computer aided design tools, and it was manufactured with standard low-voltage complementary metal-oxide-semiconductor technology, which allows smooth on-chip integration of microfluidics and microelectronics. By integrating 900 droplet detection circuits into microelectrode cells, the FPLOC has achieved large-scale integration of microfluidics and microelectronics. Compared to the full-custom and bottom-up design methods, the FPLOC provides hierarchical top-down design approach, field-programmability and dynamic manipulations of droplets for advanced microfluidic operations.

  16. Medical applications of model-based dynamic thermography

    NASA Astrophysics Data System (ADS)

    Nowakowski, Antoni; Kaczmarek, Mariusz; Ruminski, Jacek; Hryciuk, Marcin; Renkielska, Alicja; Grudzinski, Jacek; Siebert, Janusz; Jagielak, Dariusz; Rogowski, Jan; Roszak, Krzysztof; Stojek, Wojciech

    2001-03-01

    The proposal to use active thermography in medical diagnostics is promising in some applications concerning investigation of directly accessible parts of the human body. The combination of dynamic thermograms with thermal models of investigated structures gives attractive possibility to make internal structure reconstruction basing on different thermal properties of biological tissues. Measurements of temperature distribution synchronized with external light excitation allow registration of dynamic changes of local temperature dependent on heat exchange conditions. Preliminary results of active thermography applications in medicine are discussed. For skin and under- skin tissues an equivalent thermal model may be determined. For the assumed model its effective parameters may be reconstructed basing on the results of transient thermal processes. For known thermal diffusivity and conductivity of specific tissues the local thickness of a two or three layer structure may be calculated. Results of some medical cases as well as reference data of in vivo study on animals are presented. The method was also applied to evaluate the state of the human heart during the open chest cardio-surgical interventions. Reference studies of evoked heart infarct in pigs are referred, too. We see the proposed new in medical applications technique as a promising diagnostic tool. It is a fully non-invasive, clean, handy, fast and affordable method giving not only qualitative view of investigated surfaces but also an objective quantitative measurement result, accurate enough for many applications including fast screening of affected tissues.

  17. [Peculiarities of problem-based learning in medical education].

    PubMed

    Sveikauskas, Vaclovas

    2005-01-01

    In most Western universities at the end of the 20th century and at the beginning of the 21st problem-based learning is treated as a new direction of didactics or as challenge to traditional study system. Some Western researchers name problem-based learning as the method which most corresponds to the goals of modern medical education. When implementing the system of problem-based learning into traditional study systems, the junction problems can be conditioned by work principles of teacher performing tutor's functions and a traditional one. Student-oriented teaching conditions the junction between traditional approach, which emphasizes student's dependence on a teacher as information source and modern one stressing student's freedom when choosing the values of education and responsibility for his/her learning. On integrating the content of various subjects, junction problems are conditioned by disappearance of classical borders between separate subjects. When emphasizing the solution of problems in study programs, transition from the teaching concentrated on separate subject studies to the studies based on systemic problem solution can cause junction problems. Realizing the study program content oriented to community, the junction can be conditioned by insufficient openness of university to society, as, first of all, one has to train not only students and teachers but also society for new interaction with university as an institution that realizes health study program. The objective of the article is to reveal the peculiarities of problem-based learning when realizing the aims of medical education.

  18. Viscoelastic Properties and Morphology of Mumio-based Medicated Hydrogels

    NASA Astrophysics Data System (ADS)

    Zandraa, Oyunchimeg; Jelínková, Lenka; Roy, Niladri; Sáha, Tomáš; Kitano, Takeshi; Saha, Nabanita

    2011-07-01

    Novel medicated hydrogels were prepared (by moist heat treatment) with PVA, agar, mumio, mare's milk (MM), seabuckthorn oil (SB oil) and salicylic acid (SA) for wound dressing/healing application. Scanning electron micrographs (SEM) show highly porous structure of these hydrogels. The swelling behaviour of the hydrogels in physiological solution displays remarkable liquid absorption property. The knowledge obtained from rheological investigations of these-systems may be highly useful for the characterization of the newly developed topical formulations. In the present study, an oscillation frequency sweep test was used for the evaluation of storage modulus (G'), loss modulus (G″), and complex viscosity (η*) of five different formulations, over an angular frequency range from 0.1 to 100 rad.s-1. The influence of healing agents and swelling effect on the rheological properties of mumio-based medicated hydrogels was investigated to judge its application on uneven surface of body.

  19. Shape-based interactive three-dimensional medical image segmentation

    NASA Astrophysics Data System (ADS)

    Hinshaw, Kevin P.; Brinkley, James F.

    1997-04-01

    Accurate image segmentation continues to be one of the biggest challenges in medical image analysis. Simple, low- level vision techniques have had limited success in this domain because of the visual complexity of medical images. This paper presents a 3-D shape model that uses prior knowledge of an object's structure to guide the search for its boundaries. The shape model has been incorporated into scanner, an interactive software package for image segmentation. We describe a graphical user interface that was developed for finding the surface of the brain and explain how the 3-D model assists with the segmentation process. Preliminary experiments show that with this shape- based approach, a low-resolution boundary for a surface can be found with two-thirds less work for the user than with a comparable manual method.

  20. A Cloud Computing Based Patient Centric Medical Information System

    NASA Astrophysics Data System (ADS)

    Agarwal, Ankur; Henehan, Nathan; Somashekarappa, Vivek; Pandya, A. S.; Kalva, Hari; Furht, Borko

    This chapter discusses an emerging concept of a cloud computing based Patient Centric Medical Information System framework that will allow various authorized users to securely access patient records from various Care Delivery Organizations (CDOs) such as hospitals, urgent care centers, doctors, laboratories, imaging centers among others, from any location. Such a system must seamlessly integrate all patient records including images such as CT-SCANS and MRI'S which can easily be accessed from any location and reviewed by any authorized user. In such a scenario the storage and transmission of medical records will have be conducted in a totally secure and safe environment with a very high standard of data integrity, protecting patient privacy and complying with all Health Insurance Portability and Accountability Act (HIPAA) regulations.

  1. An Enhanced Biometric Based Authentication with Key-Agreement Protocol for Multi-Server Architecture Based on Elliptic Curve Cryptography.

    PubMed

    Reddy, Alavalapati Goutham; Das, Ashok Kumar; Odelu, Vanga; Yoo, Kee-Young

    2016-01-01

    Biometric based authentication protocols for multi-server architectures have gained momentum in recent times due to advancements in wireless technologies and associated constraints. Lu et al. recently proposed a robust biometric based authentication with key agreement protocol for a multi-server environment using smart cards. They claimed that their protocol is efficient and resistant to prominent security attacks. The careful investigation of this paper proves that Lu et al.'s protocol does not provide user anonymity, perfect forward secrecy and is susceptible to server and user impersonation attacks, man-in-middle attacks and clock synchronization problems. In addition, this paper proposes an enhanced biometric based authentication with key-agreement protocol for multi-server architecture based on elliptic curve cryptography using smartcards. We proved that the proposed protocol achieves mutual authentication using Burrows-Abadi-Needham (BAN) logic. The formal security of the proposed protocol is verified using the AVISPA (Automated Validation of Internet Security Protocols and Applications) tool to show that our protocol can withstand active and passive attacks. The formal and informal security analyses and performance analysis demonstrates that the proposed protocol is robust and efficient compared to Lu et al.'s protocol and existing similar protocols.

  2. An Enhanced Biometric Based Authentication with Key-Agreement Protocol for Multi-Server Architecture Based on Elliptic Curve Cryptography

    PubMed Central

    Reddy, Alavalapati Goutham; Das, Ashok Kumar; Odelu, Vanga; Yoo, Kee-Young

    2016-01-01

    Biometric based authentication protocols for multi-server architectures have gained momentum in recent times due to advancements in wireless technologies and associated constraints. Lu et al. recently proposed a robust biometric based authentication with key agreement protocol for a multi-server environment using smart cards. They claimed that their protocol is efficient and resistant to prominent security attacks. The careful investigation of this paper proves that Lu et al.’s protocol does not provide user anonymity, perfect forward secrecy and is susceptible to server and user impersonation attacks, man-in-middle attacks and clock synchronization problems. In addition, this paper proposes an enhanced biometric based authentication with key-agreement protocol for multi-server architecture based on elliptic curve cryptography using smartcards. We proved that the proposed protocol achieves mutual authentication using Burrows-Abadi-Needham (BAN) logic. The formal security of the proposed protocol is verified using the AVISPA (Automated Validation of Internet Security Protocols and Applications) tool to show that our protocol can withstand active and passive attacks. The formal and informal security analyses and performance analysis demonstrates that the proposed protocol is robust and efficient compared to Lu et al.’s protocol and existing similar protocols. PMID:27163786

  3. Architectural Choices and Challenges of Integrating Electronic Patient Questionnaires into the Electronic Medical Record to Support Patient-Centered Care

    PubMed Central

    Moore, Barbara J; Gaehde, Stephan; Curtis, Clayton

    2008-01-01

    Strategies to deliver guideline-concordant, patient-centered care during office visits sometimes impose conflicting demands on clinicians. One way to help relieve time-constrained visits and to improve the patient-centeredness of care may be through patients electronically self-reporting data that flow automatically into an EMR note for clinician confirmation or editing, relieving physicians of some data entry and rote history-gathering tasks, thus freeing up time to allow clinicians to focus on significant issues and patient concerns while also increasing the likelihood that necessary data are gathered and available for decision-making. We developed a prototype to enable such data gathering and integration into the EMR. The lack of consistent provision of interfaces by vendors for sending data into EMRs and the idiosyncrasies of any particular EMR in the context of a particular organization’s IT infrastructure and policies pose architectural choices and challenges that healthcare organizations embarking on such IT projects may need to consider. PMID:18999024

  4. Architecture for Improving Terrestrial Logistics Based on the Web of Things

    PubMed Central

    Castro, Miguel; Jara, Antonio J.; Skarmeta, Antonio

    2012-01-01

    Technological advances for improving supply chain efficiency present three key challenges for managing goods: tracking, tracing and monitoring (TTM), in order to satisfy the requirements for products such as perishable goods where the European Legislations requires them to ship within a prescribed temperature range to ensure freshness and suitability for consumption. The proposed system integrates RFID for tracking and tracing through a distributed architecture developed for heavy goods vehicles, and the sensors embedded in the SunSPOT platform for monitoring the goods transported based on the concept of the Internet of Things. This paper presents how the Internet of Things is integrated for improving terrestrial logistics offering a comprehensive and flexible architecture, with high scalability, according to the specific needs for reaching an item-level continuous monitoring solution. The major contribution from this work is the optimization of the Embedded Web Services based on RESTful (Web of Things) for the access to TTM services at any time during the transportation of goods. Specifically, it has been extended the monitoring patterns such as observe and blockwise transfer for the requirements from the continuous conditional monitoring, and for the transfer of full inventories and partial ones based on conditional queries. In definitive, this work presents an evolution of the previous TTM solutions, which were limited to trailer identification and environment monitoring, to a solution which is able to provide an exhaustive item-level monitoring, required for several use cases. This exhaustive monitoring has required new communication capabilities through the Web of Things, which has been optimized with the use and improvement of a set of communications patterns. PMID:22778657

  5. Cool Apps: Building Cryospheric Data Applications with Standards-Based Service Oriented Architecture

    NASA Astrophysics Data System (ADS)

    Oldenburg, J.; Truslove, I.; Collins, J. A.; Liu, M.; Lewis, S.; Brodzik, M.

    2012-12-01

    The National Snow and Ice Data Center (NSIDC) holds a large collection of cryospheric data, and is involved in a number of informatics research and development projects aimed at improving the discoverability and accessibility of these data. To develop high- quality software in a timely manner, we have adopted a Service- Oriented Architecture (SOA) approach for our core technical infrastructure development. Data services at NSIDC are internally exposed to other tools and applications through standards-based service interfaces. These standards include OAI-PMH (Open Archives Initiative Protocol for Metadata Harvesting), various OGC (Open Geospatial Consortium) standards including WMS (Web Map Service) and WFS (Web Feature Service), ESIP (Federation of Earth Sciences Information Partners) OpenSearch, and NSIDC-defined service endpoints which follow a RESTful architecture. By taking a standards-based approach, we are able to use off-the-shelf tools and libraries to consume, translate and broker these data services, and thus develop applications faster. Additionally, by exposing public interfaces to these services we provide valuable data services to technical collaborators; for example, NASA Reverb (http://reverb.echo.nasa.gov) uses NSIDC's WMS services. Our latest generation of web applications consume these data services directly. The most complete example of this is the Operation IceBridge Data Portal (http://nsidc.org/icebridge/ portal) which depends on many of the aforementioned services, retrieving data in several ways. The maps it displays are obtained through the use of WMS and WFS protocols from a MapServer instance hosted at NSIDC. Links to the scientific data collected on Operation IceBridge campaigns are obtained through ESIP OpenSearch requests service providers that encapsulate our metadata databases. These standards-based web services are also developed at NSIDC and are designed to be used independently of the Portal. This poster provides a visual

  6. Architecture for improving terrestrial logistics based on the Web of Things.

    PubMed

    Castro, Miguel; Jara, Antonio J; Skarmeta, Antonio

    2012-01-01

    Technological advances for improving supply chain efficiency present three key challenges for managing goods: tracking, tracing and monitoring (TTM), in order to satisfy the requirements for products such as perishable goods where the European Legislations requires them to ship within a prescribed temperature range to ensure freshness and suitability for consumption. The proposed system integrates RFID for tracking and tracing through a distributed architecture developed for heavy goods vehicles, and the sensors embedded in the SunSPOT platform for monitoring the goods transported based on the concept of the Internet of Things. This paper presents how the Internet of Things is integrated for improving terrestrial logistics offering a comprehensive and flexible architecture, with high scalability, according to the specific needs for reaching an item-level continuous monitoring solution. The major contribution from this work is the optimization of the Embedded Web Services based on RESTful (Web of Things) for the access to TTM services at any time during the transportation of goods. Specifically, it has been extended the monitoring patterns such as observe and blockwise transfer for the requirements from the continuous conditional monitoring, and for the transfer of full inventories and partial ones based on conditional queries. In definitive, this work presents an evolution of the previous TTM solutions, which were limited to trailer identification and environment monitoring, to a solution which is able to provide an exhaustive item-level monitoring, required for several use cases. This exhaustive monitoring has required new communication capabilities through the Web of Things, which has been optimized with the use and improvement of a set of communications patterns.

  7. Model-Based Systems Engineering for Capturing Mission Architecture System Processes with an Application Case Study - Orion Flight Test 1

    NASA Technical Reports Server (NTRS)

    Bonanne, Kevin H.

    2011-01-01

    Model-based Systems Engineering (MBSE) is an emerging methodology that can be leveraged to enhance many system development processes. MBSE allows for the centralization of an architecture description that would otherwise be stored in various locations and formats, thus simplifying communication among the project stakeholders, inducing commonality in representation, and expediting report generation. This paper outlines the MBSE approach taken to capture the processes of two different, but related, architectures by employing the Systems Modeling Language (SysML) as a standard for architecture description and the modeling tool MagicDraw. The overarching goal of this study was to demonstrate the effectiveness of MBSE as a means of capturing and designing a mission systems architecture. The first portion of the project focused on capturing the necessary system engineering activities that occur when designing, developing, and deploying a mission systems architecture for a space mission. The second part applies activities from the first to an application problem - the system engineering of the Orion Flight Test 1 (OFT-1) End-to-End Information System (EEIS). By modeling the activities required to create a space mission architecture and then implementing those activities in an application problem, the utility of MBSE as an approach to systems engineering can be demonstrated.

  8. The Digital Anatomist Distributed Framework and Its Applications to Knowledge-based Medical Imaging

    PubMed Central

    Brinkley, James F.; Rosse, Cornelius

    1997-01-01

    Abstract The domain of medical imaging is anatomy. Therefore, anatomic knowledge should be a rational basis for organizing and analyzing images. The goals of the Digital Anatomist Program at the University of Washington include the development of an anatomically based software framework for organizing, analyzing, visualizing and utilizing biomedical information. The framework is based on representations for both spatial and symbolic anatomic knowledge, and is being implemented in a distributed architecture in which multiple client programs on the Internet are used to update and access an expanding set of anatomical information resources. The development of this framework is driven by several practical applications, including symbolic anatomic reasoning, knowledge based image segmentation, anatomy information retrieval, and functional brain mapping. Since each of these areas involves many difficult image processing issues, our research strategy is an evolutionary one, in which applications are developed somewhat independently, and partial solutions are integrated in a piecemeal fashion, using the network as the substrate. This approach assumes that networks of interacting components can synergistically work together to solve problems larger than either could solve on its own. Each of the individual projects is described, along with evaluations that show that the individual components are solving the problems they were designed for, and are beginning to interact with each other in a synergistic manner. We argue that this synergy will increase, not only within our own group, but also among groups as the Internet matures, and that an anatomic knowledge base will be a useful means for fostering these interactions. PMID:9147337

  9. ARCHITECT: The architecture-based technology evaluation and capability tradeoff method

    NASA Astrophysics Data System (ADS)

    Griendling, Kelly A.

    The use of architectures for the design, development, and documentation of system-of-systems engineering has become a common practice in recent years. This practice became mandatory in the defense industry in 2004 when the Department of Defense Architecture Framework (DoDAF) Promulgation Memo mandated that all Department of Defense (DoD) architectures must be DoDAF compliant. Despite this mandate, there has been significant confusion and a lack of consistency in the creation and the use of the architecture products. Products are typically created as static documents used for communication and documentation purposes that are difficult to change and do not support engineering design activities and acquisition decision making. At the same time, acquisition guidance has been recently reformed to move from the bottom-up approach of the Requirements Generation System (RGS) to the top-down approach mandated by the Joint Capabilities Integration and Devel- opment System (JCIDS), which requires the use of DoDAF to support acquisition. Defense agencies have had difficulty adjusting to this new policy, and are struggling to determine how to meet new acquisition requirements. This research has developed the Architecture-based Technology Evaluation and Capability Tradeoff (ARCHITECT) Methodology to respond to these challenges and address concerns raised about the defense acquisition process, particularly the time required to implement parts of the process, the need to evaluate solutions across capability and mission areas, and the need to use a rigorous, traceable, repeatable method that utilizes modeling and simulation to better substantiate early-phase acquisition decisions. The objective is to create a capability-based systems engineering methodology for the early phases of design and acquisition (specifically Pre-Milestone A activities) which improves agility in defense acquisition by (1) streamlining the development of key elements of JCIDS and DoDAF, (2) moving the

  10. Rotorcraft-based emergency medical services in the Caribbean Basin

    NASA Technical Reports Server (NTRS)

    Smith, R. W.; Alton, L. R.

    1987-01-01

    There is a pressing need for improved health care in general and emergency health care in particular throughout the Caribbean Basin. The importance of rotorcraft as an integral part of the needed system of emergency medical care in the region was investigated. Many of the larger countries in the region currently have the needed infrastructure to implement a national system of rotorcraft-based emergency medical centers within their borders. By helping to establish a system of rotorcraft based health care centers in strategic locations in the Lesser Antilles, the U.S. can assist the islands of the region by demonstrating the concept and establishing a potential training site for the other larger countries of the region. There is sufficient demand for rotorcraft based emergency health care within the Lesser Antilles to locate one center on the island of Puerto Rico and another one of the southern-most islands. With the use of fixed wing aircraft or long range helicopters, the two rotorcraft based centers could provide the region with rapid and efficient emergency health care. The superior speed and range of the XV-15 Tilt Rotor aircraft make it an attractive possibility for emergency transport and rescue in this region.

  11. Anatomy that must be taught to a medical undergraduate: an interview-based survey in an Indian medical school.

    PubMed

    Nayak, Satheesha; Ramnarayan, K; Somayaji, S N

    2005-07-01

    Confusion still exists about the anatomy to be taught to the medical undergraduate. We did an interview-based survey at the Melaka Manipal Medical College in Manipal, India, to try to evaluate the quantum of anatomy that should be taught to the medical undergraduate. The results suggest that excluding trivia and making anatomy more clinically oriented would be advantageous. A hybrid approach to anatomy including both problem-based learning and discipline-based curricula would be a better option than the regional or systemic approaches.

  12. Perspective: Competency-based medical education: a defense against the four horsemen of the medical education apocalypse.

    PubMed

    Albanese, Mark; Mejicano, George; Gruppen, Larry

    2008-12-01

    Medical education is facing a convergence of challenges that the authors characterize as the four horsemen of the medical education apocalypse: teaching patient shortages, teacher shortages, conflicting systems, and financial problems. Rapidly expanding class sizes and new medical schools are coming online as medical student access to teaching patients is becoming increasingly difficult because of the decreasing length and increasing intensity of hospital stays, concerns about patient safety, patients who are stressed for time, teaching physician shortages and needs for increasing productivity from those who remain, and increasing emphasis on translational research. Further, medical education is facing reductions in funding from all sources, just as it is mounting its first major expansion in 40 years. The authors contend that medical education is on the verge of crisis and that little outside assistance is forthcoming. If medical education is to avoid a catastrophic decline, it will need to take steps to reinvent itself and make optimum use of all available resources. Curriculum materials developed nationally, increased reliance on simulation and standardized patient experiences, and adoption of quality-control methods such as competency-based education are suggested as ways to keep medical education vital in an environment that is increasingly preoccupied with fending off the four horsemen. The authors conclude with a call for a national dialogue about how the medical education community can address the problems represented by the four horsemen, and they offer some potential ways to maintain the vitality of medical education in the face of such overwhelming problems.

  13. A similarity-based data warehousing environment for medical images.

    PubMed

    Teixeira, Jefferson William; Annibal, Luana Peixoto; Felipe, Joaquim Cezar; Ciferri, Ricardo Rodrigues; Ciferri, Cristina Dutra de Aguiar

    2015-11-01

    A core issue of the decision-making process in the medical field is to support the execution of analytical (OLAP) similarity queries over images in data warehousing environments. In this paper, we focus on this issue. We propose imageDWE, a non-conventional data warehousing environment that enables the storage of intrinsic features taken from medical images in a data warehouse and supports OLAP similarity queries over them. To comply with this goal, we introduce the concept of perceptual layer, which is an abstraction used to represent an image dataset according to a given feature descriptor in order to enable similarity search. Based on this concept, we propose the imageDW, an extended data warehouse with dimension tables specifically designed to support one or more perceptual layers. We also detail how to build an imageDW and how to load image data into it. Furthermore, we show how to process OLAP similarity queries composed of a conventional predicate and a similarity search predicate that encompasses the specification of one or more perceptual layers. Moreover, we introduce an index technique to improve the OLAP query processing over images. We carried out performance tests over a data warehouse environment that consolidated medical images from exams of several modalities. The results demonstrated the feasibility and efficiency of our proposed imageDWE to manage images and to process OLAP similarity queries. The results also demonstrated that the use of the proposed index technique guaranteed a great improvement in query processing.

  14. Simulation of Si:P spin-based quantum computer architecture

    SciTech Connect

    Chang Yiachung; Fang Angbo

    2008-11-07

    We present realistic simulation for single and double phosphorous donors in a silicon-based quantum computer design by solving a valley-orbit coupled effective-mass equation for describing phosphorous donors in strained silicon quantum well (QW). Using a generalized unrestricted Hartree-Fock method, we solve the two-electron effective-mass equation with quantum well confinement and realistic gate potentials. The effects of QW width, gate voltages, donor separation, and donor position shift on the lowest singlet and triplet energies and their charge distributions for a neighboring donor pair in the quantum computer(QC) architecture are analyzed. The gate tunability are defined and evaluated for a typical QC design. Estimates are obtained for the duration of spin half-swap gate operation.

  15. Enhanced Engine Performance During Emergency Operation Using a Model-Based Engine Control Architecture

    NASA Technical Reports Server (NTRS)

    Csank, Jeffrey T.; Connolly, Joseph W.

    2016-01-01

    This paper discusses the design and application of model-based engine control (MBEC) for use during emergency operation of the aircraft. The MBEC methodology is applied to the Commercial Modular Aero-Propulsion System Simulation 40k (CMAPSS40k) and features an optimal tuner Kalman Filter (OTKF) to estimate unmeasured engine parameters, which can then be used for control. During an emergency scenario, normally-conservative engine operating limits may be relaxed to increase the performance of the engine and overall survivability of the aircraft; this comes at the cost of additional risk of an engine failure. The MBEC architecture offers the advantage of estimating key engine parameters that are not directly measureable. Estimating the unknown parameters allows for tighter control over these parameters, and on the level of risk the engine will operate at. This will allow the engine to achieve better performance than possible when operating to more conservative limits on a related, measurable parameter.

  16. Enhanced Engine Performance During Emergency Operation Using a Model-Based Engine Control Architecture

    NASA Technical Reports Server (NTRS)

    Csank, Jeffrey T.; Connolly, Joseph W.

    2015-01-01

    This paper discusses the design and application of model-based engine control (MBEC) for use during emergency operation of the aircraft. The MBEC methodology is applied to the Commercial Modular Aero-Propulsion System Simulation 40,000 (CMAPSS40,000) and features an optimal tuner Kalman Filter (OTKF) to estimate unmeasured engine parameters, which can then be used for control. During an emergency scenario, normally-conservative engine operating limits may be relaxed to increase the performance of the engine and overall survivability of the aircraft; this comes at the cost of additional risk of an engine failure. The MBEC architecture offers the advantage of estimating key engine parameters that are not directly measureable. Estimating the unknown parameters allows for tighter control over these parameters, and on the level of risk the engine will operate at. This will allow the engine to achieve better performance than possible when operating to more conservative limits on a related, measurable parameter.

  17. A conceptual framework to design a dimensional model based on the HL7 Clinical Document Architecture.

    PubMed

    Pecoraro, Fabrizio; Luzi, Daniela; Ricci, Fabrizio L

    2014-01-01

    This paper proposes a conceptual framework to design a dimensional model based on the HL7 Clinical Document Architecture (CDA) standard. The adoption of this framework can represent a possible solution to facilitate the integration of heterogeneous information systems in a clinical data warehouse. This can simplify the Extract, Transform and Load (ETL) procedures that are considered the most time-consuming and expensive part of the data warehouse development process. The paper describes the main activities to be carried out to design the dimensional model outlining the main advantages in the application of the proposed framework. The feasibility of our approach is also demonstrated providing a case study to define clinical indicators for quality assessment.

  18. Design and Performance Evaluation of Optical Ethernet Switching Architecture with Liquid Crystal on Silicon-Based Beam-Steering Technology

    NASA Astrophysics Data System (ADS)

    Cheng, Yuh-Jiuh; Chou, H.-H.; Shiau, Yhi; Cheng, Shu-Ying

    2016-07-01

    A non-blocking optical Ethernet switching architecture with liquid crystal on a silicon-based beam-steering switch and optical output buffer strategies are proposed. For preserving service packet sequencing and fairness of routing sequence, priority and round-robin algorithms are adopted at the optical output buffer in this research. Four methods were used to implement tunable fiber delay modules for the optical output buffers to handle Ethernet packets with variable bit-rates. The results reported are based on the simulations performed to evaluate the proposed switching architecture with traffic analysis under a traffic model captured from a real-core network.

  19. Optical Flow in a Smart Sensor Based on Hybrid Analog-Digital Architecture

    PubMed Central

    Guzmán, Pablo; Díaz, Javier; Agís, Rodrigo; Ros, Eduardo

    2010-01-01

    The purpose of this study is to develop a motion sensor (delivering optical flow estimations) using a platform that includes the sensor itself, focal plane processing resources, and co-processing resources on a general purpose embedded processor. All this is implemented on a single device as a SoC (System-on-a-Chip). Optical flow is the 2-D projection into the camera plane of the 3-D motion information presented at the world scenario. This motion representation is widespread well-known and applied in the science community to solve a wide variety of problems. Most applications based on motion estimation require work in real-time; hence, this restriction must be taken into account. In this paper, we show an efficient approach to estimate the motion velocity vectors with an architecture based on a focal plane processor combined on-chip with a 32 bits NIOS II processor. Our approach relies on the simplification of the original optical flow model and its efficient implementation in a platform that combines an analog (focal-plane) and digital (NIOS II) processor. The system is fully functional and is organized in different stages where the early processing (focal plane) stage is mainly focus to pre-process the input image stream to reduce the computational cost in the post-processing (NIOS II) stage. We present the employed co-design techniques and analyze this novel architecture. We evaluate the system’s performance and accuracy with respect to the different proposed approaches described in the literature. We also discuss the advantages of the proposed approach as well as the degree of efficiency which can be obtained from the focal plane processing capabilities of the system. The final outcome is a low cost smart sensor for optical flow computation with real-time performance and reduced power consumption that can be used for very diverse application domains. PMID:22319283

  20. Ground Optical Signal Processing Architecture for Contributing SSA Space Based Sensor Data

    NASA Astrophysics Data System (ADS)

    Koblick, D.; Klug, M.; Goldsmith, A.; Flewelling, B.; Jah, M.; Shanks, J.; Piña, R.

    2014-09-01

    The main objective of the DARPA program Orbit Outlook (O^2) is to improve the metric tracking and detection performance of the Space Situational Network (SSN) by adding a diverse low-cost network of contributing sensors to the Space Situational Awareness (SSA) mission. In order to accomplish this objective, not only must a sensor be in constant communication with a planning and scheduling system to process tasking requests, there must be an underlying framework to provide useful data products, such as angles only measurements. Existing optical signal processing implementations such as the Optical Processing Architecture at Lincoln (OPAL) are capable of converting mission data collections to angles only observations, but may be difficult for many users to obtain, support, and customize for low-cost missions and demonstration programs. The Ground Optical Signal Processing Architecture (GOSPA) will ingest raw imagery and telemetry data from a space based electro optical sensor and perform a background removal process to remove anomalous pixels, interpolate over bad pixels, and dominant temporal noise. After background removal, the streak end points and target centroids are located using a corner detection algorithm developed by Air Force Research Laboratory. These identified streak locations are then fused with the corresponding spacecraft telemetry data to determine the Right Ascension and Declination measurements with respect to time. To demonstrate the performance of GOSPA, non-rate tracking collections against a satellite in Geosynchronous Orbit are simulated from a visible optical imaging sensor in a polar Low Earth Orbit. Stars, noise and bad pixels are added to the simulated images based on look angles and sensor parameters. These collections are run through the GOSPA framework to provide angles- only measurements to the Air Force Research Laboratory Constrained Admissible Region Multiple Hypothesis Filter (CAR-MHF) in which an Initial Orbit Determination is

  1. Mapping Rule-Based And Stochastic Constraints To Connection Architectures: Implication For Hierarchical Image Processing

    NASA Astrophysics Data System (ADS)

    Miller, Michael I.; Roysam, Badrinath; Smith, Kurt R.

    1988-10-01

    Essential to the solution of ill posed problems in vision and image processing is the need to use object constraints in the reconstruction. While Bayesian methods have shown the greatest promise, a fundamental difficulty has persisted in that many of the available constraints are in the form of deterministic rules rather than as probability distributions and are thus not readily incorporated as Bayesian priors. In this paper, we propose a general method for mapping a large class of rule-based constraints to their equivalent stochastic Gibbs' distribution representation. This mapping allows us to solve stochastic estimation problems over rule-generated constraint spaces within a Bayesian framework. As part of this approach we derive a method based on Langevin's stochastic differential equation and a regularization technique based on the classical autologistic transfer function that allows us to update every site simultaneously regardless of the neighbourhood structure. This allows us to implement a completely parallel method for generating the constraint sets corresponding to the regular grammar languages on massively parallel networks. We illustrate these ideas by formulating the image reconstruction problem based on a hierarchy of rule-based and stochastic constraints, and derive a fully parallelestimator structure. We also present results computed on the AMT DAP500 massively parallel digital computer, a mesh-connected 32x32 array of processing elements which are configured in a Single-Instruction, Multiple Data stream architecture.

  2. Silicon based nano-architectures for high power lithium-ion battery anodes

    NASA Astrophysics Data System (ADS)

    Krishnan, Rahul

    Lithium-ion batteries have now become an inseparable part of modern day society as the power source for several portable electronics like cell phones, digital cameras and laptops. Their high energy density compared with other electrochemical battery systems has been their most attractive feature. This has lead to a great interest in developing lithium-ion batteries for hybrid and all-electric vehicles. Eventually such vehicles will help drastically reduce the carbon footprint making the environment cleaner and healthier. In spite of their high energy density, Li-ion batteries are known to have poor power densities. This forms a major limitation in their deployment as a power source on vehicles. Electric vehicles need power sources that can provide both high energy and power densities. This requires the development of anode, cathode and electrolyte materials that would transform the capabilities of existing Li-ion batteries. Among anode materials silicon has received great attention because of its very large theoretical capacity of ˜4200 mAh/g based on the alloy Li22Si5. It should be noted that storage of charge in the anode occurs through the alloying of Li with the host anode material. However, the large specific capacity of silicon also results in a ˜400% volume expansion which could lead to pulverization and delamination reducing the cycle life of the electrode. These failure processes are exacerbated at high rates making it extremely difficult to use silicon for high-power Li-ion battery anodes. The major research thrust supporting this Ph.D. thesis involved exploring silicon based nano-architectures that would provide high energy and power densities over a long cycle life. The key technique used to design different nano-architectures was DC Magnetron sputtering with oblique angle deposition. The main development of this research was a functionally strain graded Carbon-Aluminum-Silicon nanoscoop architecture for high-power Li-ion battery anodes. This

  3. Medical respiratory monitoring sensors based on microbend fiber loss

    NASA Astrophysics Data System (ADS)

    Zhao, Yong; Zhouxiao, Liuting; Yang, Jian; Li, Xianjing

    2016-11-01

    In this work, a medical respiratory monitoring sensor based on the microbend effect of optical fiber on light transmission is proposed. The microbend effect of multimode optical fiber is analyzed theoretically using optical theory. A respiratory signal modulator with a "sandwich" microbender structure is designed enabling the noninvasive real-time monitoring. In vitro testing showed that the proposed sensor has excellent following characteristics and can automatically discern respiratory condition, the signal-to-noise ratio can be better than 28dB.

  4. Medical Command and Control in Sea-Based Operations

    DTIC Science & Technology

    2006-01-01

    AND CONTROL IN SEA-BASED OPERATIONS Captain Arthur M. Smith, MC, U.S. Navy Reserve (Retired), and Captain Harold R. Bohman, MC, U.S. Navy Medical...Operation Desert Storm: Full Army Capability Not Achieved, GAO/NSIAD 92-175 (Washington, D.C.: 1992), p. 47. See also Arthur M. Smith, “Integrated...September 1976), pp. 694–703; Ron R. Rozin and Y. Kleinman , “Surgical Priorities of Abdominal Wounded in a Combat Situation,” Journal of Trauma 27, no. 6

  5. A Comprehensive Computer-Based Medical Information System

    PubMed Central

    David, Sidney S.

    1977-01-01

    A comupter-based medical information system has been developed for patient care and clinical investigation. It is implemented on a large digital computer and employs techniques consistent with general purpose commercially available data management systems. It has been in operation since 1971 and contains the records of approximately 1600 patients. Incoming data are received from patients and clinical staff utilizing specialized forms. A wide diversity of output, including summaries, searches and statistics are provided. The system enhances the quality of care provided to patients, optimizes physician time spent on clinical management, improves many aspects of the supporting research, and is applicable to other areas of medicine.

  6. Detectors based on silicon photomultiplier arrays for medical imaging applications

    SciTech Connect

    Llosa, G.; Barrio, J.; Cabello, J.; Lacasta, C.; Oliver, J. F.; Stankova, V.; Solaz, C.

    2011-07-01

    Silicon photomultipliers (SiPMs) have experienced a fast development and are now employed in different research fields. The availability of 2D arrays that provide information of the interaction position in the detector has had a high interest for medical imaging. Continuous crystals combined with segmented photodetectors can provide higher efficiency than pixellated crystals and very high spatial resolution. The IRIS group at IFIC is working on the development of detector heads based on continuous crystals coupled to SiPM arrays for different applications, including a small animal PET scanner in collaboration with the Univ. of Pisa and INFN Pisa, and a Compton telescope for dose monitoring in hadron therapy. (authors)

  7. Evidence-based Mobile Medical Applications in Diabetes.

    PubMed

    Drincic, Andjela; Prahalad, Priya; Greenwood, Deborah; Klonoff, David C

    2016-12-01

    This article reviews mobile medical applications that are commercially available in the United States or European Union (EU) and are (1) associated with published data of clinical outcomes in the peer-reviewed literature during the past 5 years, (2) cleared by the US Food and Drug Administration (FDA) in the United States, or (3) a recipient of a CE (Conformité Européenne) mark by the EU. Many of these applications have been shown to positively affect outcomes in the short term, but long-term studies are needed. Until more data are available, consumers and professionals can consider guidance based on FDA/CE status.

  8. Model-based segmentation of medical imagery by matching distributions.

    PubMed

    Freedman, Daniel; Radke, Richard J; Zhang, Tao; Jeong, Yongwon; Lovelock, D Michael; Chen, George T Y

    2005-03-01

    The segmentation of deformable objects from three-dimensional (3-D) images is an important and challenging problem, especially in the context of medical imagery. We present a new segmentation algorithm based on matching probability distributions of photometric variables that incorporates learned shape and appearance models for the objects of interest. The main innovation over similar approaches is that there is no need to compute a pixelwise correspondence between the model and the image. This allows for a fast, principled algorithm. We present promising results on difficult imagery for 3-D computed tomography images of the male pelvis for the purpose of image-guided radiotherapy of the prostate.

  9. Development of copper based drugs, radiopharmaceuticals and medical materials.

    PubMed

    Szymański, Paweł; Frączek, Tomasz; Markowicz, Magdalena; Mikiciuk-Olasik, Elżbieta

    2012-12-01

    Copper is one of the most interesting elements for various biomedical applications. Copper compounds show vast array of biological actions, including anti-inflammatory, anti-proliferative, biocidal and other. It also offers a selection of radioisotopes, suitable for nuclear imaging and radiotherapy. Quick progress in nanotechnology opened new possibilities for design of copper based drugs and medical materials. To date, copper has not found many uses in medicine, but number of ongoing research, as well as preclinical and clinical studies, will most likely lead to many novel applications of copper in the near future.

  10. Intention-based critiquing of guideline-oriented medical care.

    PubMed Central

    Advani, A.; Lo, K.; Shahar, Y.

    1998-01-01

    We present a methodology and tool for providing retrospective review and critiquing of guideline-based medical care given to patients. We show how our guideline representation language, Asbru, which supports the use of physicians intentions in addition to physician's actions, allows us to compare the care given to a patient at the level of the intention to treat in addition to the more detailed plan carried out. We have developed an algorithm based on this representation for retrospective quality assessment of guideline-based care. Our method takes the physician's and institution's preferences and policies into account in explaining or justifying physician deviations from the recommendations of a guideline. Images Figure 3 PMID:9929266

  11. Informatics-based Medical Procedure Assistance during Space Missions

    PubMed Central

    Iyengar, M S; Carruth, T N; Florez-Arango, J; Dunn, K

    2008-01-01

    Currently, paper-based and/or electronic together with telecommunications links to Earth-based physicians are used to assist astronaut crews perform diagnosis and treatment of medical conditions during space travel. However, these have limitations, especially during long duration missions in which telecommunications to earth-based physicians can be delayed. We describe an experimental technology called GuideView in which clinical guidelines are presented in a structured, interactive, multi-modal format and, in each step, clinical instructions are provided simultaneously in voice, text, pictures video or animations. An example application of the system to diagnosis and treatment of space Decompression Sickness is presented. Astronauts performing space walks from the International Space Station are at risk for decompression sickness because the atmospheric pressure of the Extra-vehicular Activity space- suit is significantly less that that of the interior of the Station. PMID:19048089

  12. Web-Based Architecture to Enable Compute-Intensive CAD Tools and Multi-user Synchronization in Teleradiology

    NASA Astrophysics Data System (ADS)

    Mehta, Neville; Kompalli, Suryaprakash; Chaudhary, Vipin

    Teleradiology is the electronic transmission of radiological patient images, such as x-rays, CT, or MR across multiple locations. The goal could be interpretation, consultation, or medical records keeping. Information technology solutions have enabled electronic records and their associated benefits are evident in health care today. However, salient aspects of collaborative interfaces, and computer assisted diagnostic (CAD) tools are yet to be integrated into workflow designs. The Computer Assisted Diagnostics and Interventions (CADI) group at the University at Buffalo has developed an architecture that facilitates web-enabled use of CAD tools, along with the novel concept of synchronized collaboration. The architecture can support multiple teleradiology applications and case studies are presented here.

  13. Terpyridine-based metallo-supramolecular architectures: From structure to function

    NASA Astrophysics Data System (ADS)

    El-batal, Hany

    The research and applications of functional materials continue to grow rapidly in order to match the materials and energy needs of an increasing population. In this regard, perylene is a stable, organic material that possesses a rich chemistry and unique chemical, physical, and electronic properties. The molecular organization into predesigned geometries such as: cages, dendrimers, macrocycles and polymers, can add a profound enhancement to the material functional characteristics. At the heart of metallosupramolecular chemistry, tpy-M-tpy binding is a pivotal tool to construct complex and functional architectures. This dissertation reviews the chemical, structural, physical, and electrochemical properties of perylene with an emphasize on its metallosupramolecular chemistry. The synthesis of perylene-containing bis-, tetra kis-, and hexakis-terpyridine ligands along with their corresponding heteroleptic complexes was achieved. These high molecular weight nano-dendritic architectures were characterized using 1H NMR, 13C NMR, COSY, and ESI-MS. These complexes exhibit broad absorption spectra (250-625 nm) and high molar absorption coefficients that are proportional to the number of photoactive units. The synthesis of supramolecular dyes based on motifs connected to perylene-core either in bay- or peri-positions was demonastrated. The structures of these materials were confirmed using a combination of 1H NMR, 13C NMR, COSY, ESI-MS, and their electrochemical properties were studied via Cyclic Voltametry. These dyes were utilized as active ingredients for DSSCs, of which the photovoltaic properties were described. Fluorescent cyclic metallosupramolecular architectures were obtained via mediated self-assembly of two aminobisterpyridine containing perylene ligands that were synthesized in a multistep procedure, the chemical structure and purity of both ligands and complexes were assured using a combination of 1H NMR, 13C NMR, COSY, and ESI-MS. DOSY was utilized to

  14. An optimized web-based approach for collaborative stereoscopic medical visualization

    PubMed Central

    Kaspar, Mathias; Parsad, Nigel M; Silverstein, Jonathan C

    2013-01-01

    Objective Medical visualization tools have traditionally been constrained to tethered imaging workstations or proprietary client viewers, typically part of hospital radiology systems. To improve accessibility to real-time, remote, interactive, stereoscopic visualization and to enable collaboration among multiple viewing locations, we developed an open source approach requiring only a standard web browser with no added client-side software. Materials and Methods Our collaborative, web-based, stereoscopic, visualization system, CoWebViz, has been used successfully for the past 2 years at the University of Chicago to teach immersive virtual anatomy classes. It is a server application that streams server-side visualization applications to client front-ends, comprised solely of a standard web browser with no added software. Results We describe optimization considerations, usability, and performance results, which make CoWebViz practical for broad clinical use. We clarify technical advances including: enhanced threaded architecture, optimized visualization distribution algorithms, a wide range of supported stereoscopic presentation technologies, and the salient theoretical and empirical network parameters that affect our web-based visualization approach. Discussion The implementations demonstrate usability and performance benefits of a simple web-based approach for complex clinical visualization scenarios. Using this approach overcomes technical challenges that require third-party web browser plug-ins, resulting in the most lightweight client. Conclusions Compared to special software and hardware deployments, unmodified web browsers enhance remote user accessibility to interactive medical visualization. Whereas local hardware and software deployments may provide better interactivity than remote applications, our implementation demonstrates that a simplified, stable, client approach using standard web browsers is sufficient for high quality three

  15. An architecture for the autonomous generation of preference-based trajectories

    NASA Astrophysics Data System (ADS)

    Lennon, Jamie

    Numerous techniques exist to optimize aircraft and spacecraft trajectories over cost functions that include terms such as fuel, time, and separation from obstacles. Relative weighting factors can dramatically alter solution characteristics, and engineers often must manually adjust either cost weights or the trajectory itself to obtain desirable solutions. Further, when humans and robots work together, or when humans task robots, they may express their performance expectations in a "fuzzy" natural language fashion, or else as an uncertain range of more or less acceptable values. This work describes a software architecture which accepts both fuzzy linguistic and hard numeric constraints on trajectory performance and, using a trajectory generator provided by the user, automatically constructs trajectories to meet these specifications as closely as possible. The system respects hard constraints imposed by system dynamics or by the user, and will not let the user's preferences interfere with the system and user needs. The architecture's evaluation agent translates these requirements into cost functional weights expected to produce the desired motion characteristics. The quality of the resulting full-state trajectory is then evaluated based on a set of computed trajectory features compared to the specified constraints. If constraints are not met, the cost functional weights are adjusted according to precomputed heuristic equations. Heuristics are not generated in an ad hoc fashion, but are instead the result of a systematic testing of the simulated system under a range of simple conditions. The system is tested in a 2DOF linear and a 6DOF nonlinear domain with a variety of constraints and in the presence of obstacles. Results show that the system consistently meets all hard numeric constraints placed on the trajectory. Desired characteristics are often attainable or else, in those cases where they are discounted in favor of the hard constraints, failed by small margins

  16. The development of microbatteries based on three-dimensional architectures for autonomous micro devices

    NASA Astrophysics Data System (ADS)

    Min, Hong-Seok

    2007-12-01

    The goal of fabricating three-dimensional (3D) microbatteries is to improve upon the performance of 2D microbatteries or thin-film batteries by reconfiguring existing materials in a more advanced architecture. 3D battery architectures offer a new approach for miniaturized power sources. These batteries are designed to have a small areal foot print and yet provide sufficient power and energy density to operate autonomous MEMS devices. The more convenient approaches for fabricating such batteries are based on micromachining techniques such as electrodeposition of high aspect ratio metal rods in an array configuration. Three types of three-dimensional microbatteries were fabricated and characterized: Ni-Zn, zinc-air, and Ag-Zn. These different types of microbatteries use different chemistries but all have the common feature of an out-of-plane array of micro-post electrodes. A 3D Ni-Zn microbattery was fabricated and demonstrated proper charge-discharge behavior for the first few cycles. The development of 3D zinc-air microbattery showed high discharge capability under various discharge conditions. Furthermore, performance of 3D zinc-air microbattery was demonstrated by successfully powering an electronic device. During discharge, the 3D zinc-air microbattery exhibited an electrode reaction which formed hollow ZnO electrodes by the Kirkendall effect. This electrode reaction strongly supports the functionality of the 3D microbattery. The fabrication of the Ag-Zn microbattery was accomplished by Ag electrode formation, separator coating, and Zn sedimentation. Due to imperfections in the separator coating, the 3D Ag-Zn microbattery had electrical shorts.

  17. An efficient neural network based method for medical image segmentation.

    PubMed

    Torbati, Nima; Ayatollahi, Ahmad; Kermani, Ali

    2014-01-01

    The aim of this research is to propose a new neural network based method for medical image segmentation. Firstly, a modified self-organizing map (SOM) network, named moving average SOM (MA-SOM), is utilized to segment medical images. After the initial segmentation stage, a merging process is designed to connect the objects of a joint cluster together. A two-dimensional (2D) discrete wavelet transform (DWT) is used to build the input feature space of the network. The experimental results show that MA-SOM is robust to noise and it determines the input image pattern properly. The segmentation results of breast ultrasound images (BUS) demonstrate that there is a significant correlation between the tumor region selected by a physician and the tumor region segmented by our proposed method. In addition, the proposed method segments X-ray computerized tomography (CT) and magnetic resonance (MR) head images much better than the incremental supervised neural network (ISNN) and SOM-based methods.

  18. RMAIS: RFID-based medication Adherence Intelligence System.

    PubMed

    McCall, Corey; Maynes, Branden; Zou, Cliff C; Zhang, Ning J

    2010-01-01

    There has been compelling evidence that outpatients, especially those who are elderly or taking multiple complexly scheduled drugs, are not taking their medicines as directed, leading to unnecessary disease progression, complications, functional disabilities, lower quality of life, and even mortality. Existing technologies for monitoring and improving drug adherence are either costly or too complicated for general patients to use. In this paper, we introduce the detailed design and the complete prototype of a marketable Radio-Frequency Identification (RFID)-based Medication Adherence Intelligence System (RMAIS) that can be conveniently used at a residential home by ordinary patients. RMAIS is designed to maintain patients' independence and enable them to take multiple daily medicine dosages of the right amount at the right time. The system is patient-centered and user-friendly by reminding a patient of the prescribed time for medication and dispensing it in a fully automatic and fool-proof way. This is achieved mainly due to its novel design of a motorized rotation platform and the smooth integration of a scale, an RFID reader, and the rotation platform. In addition, this system has an Internet-based notification function that is used to alert the patient when it is time to take medicine as well as report deviations from the prescribed schedule to the primary care physicians or pharmacists.

  19. Infrared laser-based sensing in medical applications

    NASA Astrophysics Data System (ADS)

    Sigrist, Markus W.; Bartlome, Richard; Gianella, Michele

    2010-01-01

    Laser-spectroscopic applications in medicine increase in importance. We present two medical applications of laser-based analyses of trace gases. The analysis of exhaled breath concerns the determination of the D/H isotope ratio after intake of a small amount of heavy water. The D/H isotope ratio can be used to deduce the total body water weight and lays the foundation for many other laser-based clinical applications. An elevated D/H ratio could be monitored in breath samples up to 30 days after ingestion of only 5 ml of D2O. A second example concerns the analysis of surgical smoke produced in minimally invasive laparoscopic surgery with electroknives. The quantitative determination of harmless and hazardous compounds down to the ppm level is demonstrated. A specific example is the presence of sevoflurane at concentrations of 80 to 300 ppm, an anesthetic, which to our knowledge is measured for the first time in an abdominal cavity.

  20. Blind forensics in medical imaging based on Tchebichef image moments.

    PubMed

    Huang, H; Coatrieux, G; Shu, H Z; Luo, L M; Roux, Ch

    2011-01-01

    In this paper, we present a blind forensic approach for the detection of global image modifications like filtering, lossy compression, scaling and so on. It is based on a new set of image features we proposed, called Histogram statistics of Reorganized Block-based Tchebichef moments (HRBT) features, and which are used as input of a set of classifiers we learned to discriminate tampered images from original ones. In this article, we compare the performances of our features with others proposed schemes from the literature in application to different medical image modalities (MRI, X-Ray …). Experimental results show that our HRBT features perform well and in some cases better than other features.

  1. Physics-based shape deformations for medical image analysis

    NASA Astrophysics Data System (ADS)

    Hamarneh, Ghassan; McInerney, Tim

    2003-05-01

    Powerful, flexible shape models of anatomical structures are required for robust, automatic analysis of medical images. In this paper we investigate a physics-based shape representation and deformation method in an effort to meet these requirements. Using a medial-based spring-mass mesh model, shape deformations are produced via the application of external forces or internal spring actuation. The range of deformations includes bulging, stretching, bending, and tapering at different locations, scales, and with varying amplitudes. Springs are actuated either by applying deformation operators or by activating statistical modes of variation obtained via a hierarchical regional principal component analysis. We demonstrate results on both synthetic data and on a spring-mass model of the corpus callosum, obtained from 2D mid-sagittal brain Magnetic Resonance (MR) Images.

  2. Compression-based aggregation model for medical web services.

    PubMed

    Al-Shammary, Dhiah; Khalil, Ibrahim

    2010-01-01

    Many organizations such as hospitals have adopted Cloud Web services in applying their network services to avoid investing heavily computing infrastructure. SOAP (Simple Object Access Protocol) is the basic communication protocol of Cloud Web services that is XML based protocol. Generally,Web services often suffer congestions and bottlenecks as a result of the high network traffic that is caused by the large XML overhead size. At the same time, the massive load on Cloud Web services in terms of the large demand of client requests has resulted in the same problem. In this paper, two XML-aware aggregation techniques that are based on exploiting the compression concepts are proposed in order to aggregate the medical Web messages and achieve higher message size reduction.

  3. Novel Space-based Solar Power Technologies and Architectures for Earth and Beyond

    NASA Technical Reports Server (NTRS)

    Howell, Joe T.; Fikes, John C.; O'Neill, Mark J.

    2005-01-01

    Research, development and studies of novel space-based solar power systems, technologies and architectures for Earth and beyond are needed to reduce the cost of clean electrical power for terrestrial use and to provide a stepping stone for providing an abundance of power in space, i.e., manufacturing facilities, tourist facilities, delivery of power between objects in space, and between space and surface sites. The architectures, technologies and systems needed for space to Earth applications may also be used for in-space applications. Advances in key technologies, i.e., power generation, power management and distribution, power beaming and conversion of beamed power are needed to achieve the objectives of both terrestrial and extraterrestrial applications. Power beaming or wireless power transmission (WPT) can involve lasers or microwaves along with the associated power interfaces. Microwave and laser transmission techniques have been studied with several promising approaches to safe and efficient WPT identified. These investigations have included microwave phased array transmitters, as well as laser transmission and associated optics. There is a need to produce "proof-of-concept" validation of critical WPT technologies for both the near-term, as well as far-term applications. Investments may be harvested in near-term beam safe demonstrations of commercial WPT applications. Receiving sites (users) include ground-based stations for terrestrial electrical power, orbital sites to provide power for satellites and other platforms, future space elevator systems, space vehicle propulsion, and space to surface sites. This paper briefly discusses achieving a promising approach to the solar power generation and beamed power conversion. The approach is based on a unique high-power solar concentrator array called Stretched Lens Array (SLA) for both solar power generation and beamed power conversion. Since both versions (solar and laser) of SLA use many identical components

  4. A Client-Server Architecture for an Instructional Environment Based on Computer Networks and the Internet.

    ERIC Educational Resources Information Center

    Guidon, Jacques; Pierre, Samuel

    1996-01-01

    Discusses the use of computers in education and training and proposes a client-server architecture for an experimental computer environment as an approach to a virtual classroom. Highlights include the World Wide Web and client software, document delivery, hardware architecture, and Internet resources and services. (Author/LRW)

  5. ARCHITECTURE OF PLANETARY SYSTEMS BASED ON KEPLER DATA: NUMBER OF PLANETS AND COPLANARITY

    SciTech Connect

    Fang, Julia; Margot, Jean-Luc

    2012-12-20

    We investigated the underlying architecture of planetary systems by deriving the distribution of planet multiplicity (number of planets) and the distribution of orbital inclinations based on the sample of planet candidates discovered by the Kepler mission. The scope of our study included solar-like stars and planets with orbital periods less than 200 days and with radii between 1.5 and 30 Earth radii, and was based on Kepler planet candidates detected during Quarters 1-6. We created models of planetary systems with different distributions of planet multiplicity and inclinations, simulated observations of these systems by Kepler, and compared the properties of the transits of detectable objects to actual Kepler planet detections. Specifically, we compared with both the Kepler sample's transit numbers and normalized transit duration ratios in order to determine each model's goodness of fit. We did not include any constraints from radial velocity surveys. Based on our best-fit models, 75%-80% of planetary systems have one or two planets with orbital periods less than 200 days. In addition, over 85% of planets have orbital inclinations less than 3 Degree-Sign (relative to a common reference plane). This high degree of coplanarity is comparable to that seen in our solar system. These results have implications for planet formation and evolution theories. Low inclinations are consistent with planets forming in a protoplanetary disk, followed by evolution without significant and lasting perturbations from other bodies capable of increasing inclinations.

  6. Knowledge base and sensor bus messaging service architecture for critical tsunami warning and decision-support

    NASA Astrophysics Data System (ADS)

    Sabeur, Z. A.; Wächter, J.; Middleton, S. E.; Zlatev, Z.; Häner, R.; Hammitzsch, M.; Loewe, P.

    2012-04-01

    The intelligent management of large volumes of environmental monitoring data for early tsunami warning requires the deployment of robust and scalable service oriented infrastructure that is supported by an agile knowledge-base for critical decision-support In the TRIDEC project (TRIDEC 2010-2013), a sensor observation service bus of the TRIDEC system is being developed for the advancement of complex tsunami event processing and management. Further, a dedicated TRIDEC system knowledge-base is being implemented to enable on-demand access to semantically rich OGC SWE compliant hydrodynamic observations and operationally oriented meta-information to multiple subscribers. TRIDEC decision support requires a scalable and agile real-time processing architecture which enables fast response to evolving subscribers requirements as the tsunami crisis develops. This is also achieved with the support of intelligent processing services which specialise in multi-level fusion methods with relevance feedback and deep learning. The TRIDEC knowledge base development work coupled with that of the generic sensor bus platform shall be presented to demonstrate advanced decision-support with situation awareness in context of tsunami early warning and crisis management.

  7. A GIS-based simulation architecture and prototype for realistic spectral scene generation of vegetated areas

    NASA Astrophysics Data System (ADS)

    Fink, Christopher E.; Moulton, Joseph R., Jr.; Ortalano, Michael; Helmsen, John; Soiguine, Alexander; Kaplan, Raymond; Seng, William; Haren, Raymond E.

    2004-08-01

    Vehicles concealed in highly cluttered, vegetated scene environments pose significant challenges for passive sensor systems and algorithms. System analysts working hyperspectral exploitation research require an at-aperture simulation capability that allows them to reliably investigate beyond the highly-limited scenarios that expensive field data sets afford. To be useful to the analyst, such a simulation should address the following requirements: (1) the ability to easily generate scene representations for arbitrary Earth regions of tactical interest; (2) the ability to represent scene components, like terrain, trees and bushes, to an extremely high spatial resolution for calculation of accurate multiple spectral reflections, occlusions and shadowing; (3) the ability to stimulate the 3D scene with realistic natural spectral irradiances for arbitrary 3D model atmospheres; (4) the ability to appropriately integrate constantly improving, rigorous thermal, spectral signature and atmospheric propagation models; (5) the ability to efficiently render at-aperture hyperspectral data sets in a reasonable run-time. Herein the authors describe their work toward a comprehensive ray-tracer-based simulation architecture and prototype capability that addresses these requirements. They describe their development of a GIS-based toolset for database generation, tools for 3D vegetated terrain-model development, and a prototype raytracer-based spectral scene generator.

  8. Image-Based Modeling Techniques for Architectural Heritage 3d Digitalization: Limits and Potentialities

    NASA Astrophysics Data System (ADS)

    Santagati, C.; Inzerillo, L.; Di Paola, F.

    2013-07-01

    3D reconstruction from images has undergone a revolution in the last few years. Computer vision techniques use photographs from data set collection to rapidly build detailed 3D models. The simultaneous applications of different algorithms (MVS), the different techniques of image matching, feature extracting and mesh optimization are inside an active field of research in computer vision. The results are promising: the obtained models are beginning to challenge the precision of laser-based reconstructions. Among all the possibilities we can mainly distinguish desktop and web-based packages. Those last ones offer the opportunity to exploit the power of cloud computing in order to carry out a semi-automatic data processing, thus allowing the user to fulfill other tasks on its computer; whereas desktop systems employ too much processing time and hard heavy approaches. Computer vision researchers have explored many applications to verify the visual accuracy of 3D model but the approaches to verify metric accuracy are few and no one is on Autodesk 123D Catch applied on Architectural Heritage Documentation. Our approach to this challenging problem is to compare the 3Dmodels by Autodesk 123D Catch and 3D models by terrestrial LIDAR considering different object size, from the detail (capitals, moldings, bases) to large scale buildings for practitioner purpose.

  9. Underlying Architecture of Planetary Systems Based on Kepler Data: Number of Planets and Coplanarity

    NASA Astrophysics Data System (ADS)

    Fang, Julia; Margot, J. L.

    2012-10-01

    We investigated the underlying architecture of planetary systems by deriving the distribution of planet multiplicity (number of planets) and the distribution of orbital inclinations based on the sample of planet candidates discovered by the Kepler mission. The scope of our study included solar-like stars and planets with orbital periods less than 200 days and with radii between 1.5 and 30 Earth radii, and was based on Kepler planet candidates detected during Quarters 1 through 6. Our analysis improves on previous work by including all available quarters, extending to 200-day periods, and fitting models to observables such as normalized transit duration ratios that contain information on mutual orbital inclinations; these improvements lend to a deeper investigation of the intrinsic distributions of planetary systems. We created models of planetary systems with different distributions of planet multiplicity and orbital inclinations, simulated observations of these systems by Kepler, and compared the number and properties of the transits of detectable objects to actual Kepler planet detections. Based on the underlying distributions of our best-fit models, 75-80% of planetary systems have 1 or 2 planets with orbital periods less than 200 days. In addition, over 85% of planets have orbital inclinations less than 3 degrees. This high degree of coplanarity is comparable to that seen in our Solar System, with the exception of Mercury. These results provide important constraints and insights into theories of planet formation and evolution.

  10. A Model-Based Study of On-Board Data Processing Architecture for Balloon-Borne Aurora Observation

    NASA Technical Reports Server (NTRS)

    Lim, Chester

    2011-01-01

    This paper discusses an application of ISAAC design methodology to a balloon-borne payload electronic system for aurora observation. The methodology is composed of two phases, high level design and low level implementation, the focus of this paper is on the high level design. This paper puts the system architecture in the context of a balloon based application but it can be generalized to any airborne/space-borne application. The system architecture includes a front-end detector, its corresponding data processing unit, and a controller. VisualSim has been used to perform modeling and simulations to explore the entire design space, finding optimal solutions that meet system requirements.

  11. Functional architectures based on self-assembly of bio-inspired dipeptides: Structure modulation and its photoelectronic applications.

    PubMed

    Chen, Chengjun; Liu, Kai; Li, Junbai; Yan, Xuehai

    2015-11-01

    Getting inspiration from nature and further developing functional architectures provides an effective way to design innovative materials and systems. Among bio-inspired materials, dipeptides and its self-assembled architectures with functionalities have recently been the subject of intensive studies. However, there is still a great challenge to explore its applications likely due to the lack of effective adaptation of their self-assembled structures as well as a lack of understanding of the self-assembly mechanisms. In this context, taking diphenylalanine (FF, a core recognition motif for molecular self-assembly of the Alzheimer's β-amyloid polypeptides) as a model of bio-inspired dipeptides, recent strategies on modulation of dipeptide-based architectures were introduced with regard to both covalent (architectures modulation by coupling functional groups) and non-covalent ways (controlled architectures by different assembly pathways). Then, applications are highlighted in some newly emerging fields of innovative photoelectronic devices and materials, such as artificial photosynthetic systems for renewable solar energy storage and renewable optical waveguiding materials for optoelectronic devices. At last, the challenges and future perspectives of these bio-inspired dipeptides are also addressed.

  12. Context predictor based sparse sensing technique and smart transmission architecture for IoT enabled remote health monitoring applications.

    PubMed

    Sai Kiran, M P R; Rajalakshmi, P; Acharyya, Amit

    2014-01-01

    In hyperconnectivity scenario, managing the amount of data acquired from sensors in the Body Area Networks (BANs) is one of the major issues. In this paper we propose an on-chip context predictor based sparse sensing technology with smart transmission architecture which makes use of confidence interval calculation from the features that present in the data, thereby achieving statistical guarantee. The proposed architecture uses intelligent sparse sensing, which eradicates the collection of redundant data, thereby reducing the amount of data generated. For the performance analysis, we considered ECG data acquisition and transmission system. The proposed architecture when applied on the data collected from 10 patients reduces the duty cycle of the sensing unit to 27.99%, by achieving an energy saving of 72% and the mean deviation of sampled data from the original data is 2%.

  13. Introducing keytagging, a novel technique for the protection of medical image-based tests.

    PubMed

    Rubio, Óscar J; Alesanco, Álvaro; García, José

    2015-08-01

    This paper introduces keytagging, a novel technique to protect medical image-based tests by implementing image authentication, integrity control and location of tampered areas, private captioning with role-based access control, traceability and copyright protection. It relies on the association of tags (binary data strings) to stable, semistable or volatile features of the image, whose access keys (called keytags) depend on both the image and the tag content. Unlike watermarking, this technique can associate information to the most stable features of the image without distortion. Thus, this method preserves the clinical content of the image without the need for assessment, prevents eavesdropping and collusion attacks, and obtains a substantial capacity-robustness tradeoff with simple operations. The evaluation of this technique, involving images of different sizes from various acquisition modalities and image modifications that are typical in the medical context, demonstrates that all the aforementioned security measures can be implemented simultaneously and that the algorithm presents good scalability. In addition to this, keytags can be protected with standard Cryptographic Message Syntax and the keytagging process can be easily combined with JPEG2000 compression since both share the same wavelet transform. This reduces the delays for associating keytags and retrieving the corresponding tags to implement the aforementioned measures to only ≃30 and ≃90ms respectively. As a result, keytags can be seamlessly integrated within DICOM, reducing delays and bandwidth when the image test is updated and shared in secure architectures where different users cooperate, e.g. physicians who interpret the test, clinicians caring for the patient and researchers.

  14. Drug-related problems associated with self-medication and medication guided by prescription: A pharmacy-based survey

    PubMed Central

    Panda, Abinash; Pradhan, Supriya; Mohapatra, Gurukrushna; Mohapatra, Jigyansa

    2016-01-01

    Objectives: The objective of this study is to identify and compare the nature of the drug-related problems (DRPs) associated with self-medication and non-self-medication (drug use guided by a prescription). Materials and Methods: The cross-sectional, observational study was conducted on 1100 adult participants at a convenience sample of six retail private pharmacy counters. The data collection form was based on the Pharmaceutical Care Network Europe version 6.2 classification for DRPs. Descriptive statistics was used to represent the prevalence of DRPs. Chi-square test was used to find out the association between the type of medication and DRPs. Odds ratio (OR) with confidence interval (CI) was computed to find the factors determining the occurrence of DRPs. P < 0.05 was considered to be statistically significant. Data were analyzed using SPSS version 16.0. Results: The prevalence of self-medication was 18.72%. The prevalence of DRPs was 17.36%. In the self-medication group, the prevalence of DRPs was high (40.78%) as compared to the non-self-medication group (11.97%). DRP related to inappropriate drug dosing was observed in 44.83% and 40.45% subjects in self-medication and non-self-medication group, respectively (P < 0.001). The subjects in the self-medication group were about 5 times likely to have a DRP (OR: 5.06, CI: 3.59-7.14, P < 0.001). Conclusions: Self-medication is associated with a higher risk of various DRPs. Since retail pharmacy outlet is often the first point of contact between the patient and the health care system in a developing country, interventions like drug information activities at the retail pharmacy is likely to bring down the DRPs associated with self-medication. PMID:27721536

  15. A PSO-based rule extractor for medical diagnosis.

    PubMed

    Hsieh, Yi-Zeng; Su, Mu-Chun; Wang, Pa-Chun

    2014-06-01

    One of the major bottlenecks in applying conventional neural networks to the medical field is that it is very difficult to interpret, in a physically meaningful way, because the learned knowledge is numerically encoded in the trained synaptic weights. In one of our previous works, we proposed a class of Hyper-Rectangular Composite Neural Networks (HRCNNs) of which synaptic weights can be interpreted as a set of crisp If-Then rules; however, a trained HRCNN may result in some ineffective If-Then rules which can only justify very few positive examples (i.e., poor generalization). This motivated us to propose a PSO-based Fuzzy Hyper-Rectangular Composite Neural Network (PFHRCNN) which applies particle swarm optimization (PSO) to trim the rules generated by a trained HRCNN while the recognition performance will not be degraded or even be improved. The performance of the proposed PFHRCNN is demonstrated on three benchmark medical databases including liver disorders data set, the breast cancer data set and the Parkinson's disease data set.

  16. Internet-based survey on medical manga in Japan.

    PubMed

    Kishi, Yukiko; Matsumura, Tomoko; Murishige, Naoko; Kodama, Yuko; Hatanaka, Nobuyo; Takita, Morihito; Sakamoto, Kenjiro; Hamaki, Tamae; Kusumi, Eiji; Kobayashi, Kazuhiko; Yuji, Koichiro; Narimatsu, Hiroto; Kami, Masahiro

    2011-10-01

    The more manga (Japanese graphic novels) communicate medical information, the more people are likely to be influenced by manga. We investigated through an Internet search using Google the characteristics of medical manga published in Japan, defined as those in which the main character is a medical professional and that occur in a medical setting. As of December 2008, 173 medical manga had been published. For a period of time after the first medical manga by Osamu Tezuka in 1970, the number of publications maintained a steady level, but increased rapidly in the mid 1980s. The professions of the protagonist were 134 doctors, 19 nurses, 3 dentists, 3 medical students, and 1 nursing student. Although the main character was mostly a doctor, manga featuring paramedical professionals have increased since 1990s. Medical manga may be a powerful tool for increasing the awareness of the public regarding medicine.

  17. Evaluating Learning among Undergraduate Medical Students in Schools with Traditional and Problem-Based Curricula

    ERIC Educational Resources Information Center

    Meo, Sultan Ayoub

    2013-01-01

    This study aimed to assess knowledge and skills in a respiratory physiology course in traditional versus problem-based learning (PBL) groups in two different medical schools. Two different undergraduate medical schools were selected for this study. The first medical school followed the traditional [lecture-based learning (LBL)] curriculum, and the…

  18. The Human Brainnetome Atlas: A New Brain Atlas Based on Connectional Architecture.

    PubMed

    Fan, Lingzhong; Li, Hai; Zhuo, Junjie; Zhang, Yu; Wang, Jiaojian; Chen, Liangfu; Yang, Zhengyi; Chu, Congying; Xie, Sangma; Laird, Angela R; Fox, Peter T; Eickhoff, Simon B; Yu, Chunshui; Jiang, Tianzi

    2016-08-01

    The human brain atlases that allow correlating brain anatomy with psychological and cognitive functions are in transition from ex vivo histology-based printed atlases to digital brain maps providing multimodal in vivo information. Many current human brain atlases cover only specific structures, lack fine-grained parcellations, and fail to provide functionally important connectivity information. Using noninvasive multimodal neuroimaging techniques, we designed a connectivity-based parcellation framework that identifies the subdivisions of the entire human brain, revealing the in vivo connectivity architecture. The resulting human Brainnetome Atlas, with 210 cortical and 36 subcortical subregions, provides a fine-grained, cross-validated atlas and contains information on both anatomical and functional connections. Additionally, we further mapped the delineated structures to mental processes by reference to the BrainMap database. It thus provides an objective and stable starting point from which to explore the complex relationships between structure, connectivity, and function, and eventually improves understanding of how the human brain works. The human Brainnetome Atlas will be made freely available for download at http://atlas.brainnetome.org, so that whole brain parcellations, connections, and functional data will be readily available for researchers to use in their investigations into healthy and pathological states.

  19. Classifier models and architectures for EEG-based neonatal seizure detection.

    PubMed

    Greene, B R; Marnane, W P; Lightbody, G; Reilly, R B; Boylan, G B

    2008-10-01

    Neonatal seizures are the most common neurological emergency in the neonatal period and are associated with a poor long-term outcome. Early detection and treatment may improve prognosis. This paper aims to develop an optimal set of parameters and a comprehensive scheme for patient-independent multi-channel EEG-based neonatal seizure detection. We employed a dataset containing 411 neonatal seizures. The dataset consists of multi-channel EEG recordings with a mean duration of 14.8 h from 17 neonatal patients. Early-integration and late-integration classifier architectures were considered for the combination of information across EEG channels. Three classifier models based on linear discriminants, quadratic discriminants and regularized discriminants were employed. Furthermore, the effect of electrode montage was considered. The best performing seizure detection system was found to be an early integration configuration employing a regularized discriminant classifier model. A referential EEG montage was found to outperform the more standard bipolar electrode montage for automated neonatal seizure detection. A cross-fold validation estimate of the classifier performance for the best performing system yielded 81.03% of seizures correctly detected with a false detection rate of 3.82%. With post-processing, the false detection rate was reduced to 1.30% with 59.49% of seizures correctly detected. These results represent a comprehensive illustration that robust reliable patient-independent neonatal seizure detection is possible using multi-channel EEG.

  20. Model-Driven Methodology for Rapid Deployment of Smart Spaces Based on Resource-Oriented Architectures

    PubMed Central

    Corredor, Iván; Bernardos, Ana M.; Iglesias, Josué; Casar, José R.

    2012-01-01

    Advances in electronics nowadays facilitate the design of smart spaces based on physical mash-ups of sensor and actuator devices. At the same time, software paradigms such as Internet of Things (IoT) and Web of Things (WoT) are motivating the creation of technology to support the development and deployment of web-enabled embedded sensor and actuator devices with two major objectives: (i) to integrate sensing and actuating functionalities into everyday objects, and (ii) to easily allow a diversity of devices to plug into the Internet. Currently, developers who are applying this Internet-oriented approach need to have solid understanding about specific platforms and web technologies. In order to alleviate this development process, this research proposes a Resource-Oriented and Ontology-Driven Development (ROOD) methodology based on the Model Driven Architecture (MDA). This methodology aims at enabling the development of smart spaces through a set of modeling tools and semantic technologies that support the definition of the smart space and the automatic generation of code at hardware level. ROOD feasibility is demonstrated by building an adaptive health monitoring service for a Smart Gym. PMID:23012544

  1. Lightweight filter architecture for energy efficient mobile vehicle localization based on a distributed acoustic sensor network.

    PubMed

    Kim, Keonwook

    2013-08-23

    The generic properties of an acoustic signal provide numerous benefits for localization by applying energy-based methods over a deployed wireless sensor network (WSN). However, the signal generated by a stationary target utilizes a significant amount of bandwidth and power in the system without providing further position information. For vehicle localization, this paper proposes a novel proximity velocity vector estimator (PVVE) node architecture in order to capture the energy from a moving vehicle and reject the signal from motionless automobiles around the WSN node. A cascade structure between analog envelope detector and digital exponential smoothing filter presents the velocity vector-sensitive output with low analog circuit and digital computation complexity. The optimal parameters in the exponential smoothing filter are obtained by analytical and mathematical methods for maximum variation over the vehicle speed. For stationary targets, the derived simulation based on the acoustic field parameters demonstrates that the system significantly reduces the communication requirements with low complexity and can be expected to extend the operation time considerably.

  2. A novel architecture for information retrieval system based on semantic web

    NASA Astrophysics Data System (ADS)

    Zhang, Hui

    2011-12-01

    Nowadays, the web has enabled an explosive growth of information sharing (there are currently over 4 billion pages covering most areas of human endeavor) so that the web has faced a new challenge of information overhead. The challenge that is now before us is not only to help people locating relevant information precisely but also to access and aggregate a variety of information from different resources automatically. Current web document are in human-oriented formats and they are suitable for the presentation, but machines cannot understand the meaning of document. To address this issue, Berners-Lee proposed a concept of semantic web. With semantic web technology, web information can be understood and processed by machine. It provides new possibilities for automatic web information processing. A main problem of semantic web information retrieval is that when these is not enough knowledge to such information retrieval system, the system will return to a large of no sense result to uses due to a huge amount of information results. In this paper, we present the architecture of information based on semantic web. In addiction, our systems employ the inference Engine to check whether the query should pose to Keyword-based Search Engine or should pose to the Semantic Search Engine.

  3. Model-driven methodology for rapid deployment of smart spaces based on resource-oriented architectures.

    PubMed

    Corredor, Iván; Bernardos, Ana M; Iglesias, Josué; Casar, José R

    2012-01-01

    Advances in electronics nowadays facilitate the design of smart spaces based on physical mash-ups of sensor and actuator devices. At the same time, software paradigms such as Internet of Things (IoT) and Web of Things (WoT) are motivating the creation of technology to support the development and deployment of web-enabled embedded sensor and actuator devices with two major objectives: (i) to integrate sensing and actuating functionalities into everyday objects, and (ii) to easily allow a diversity of devices to plug into the Internet. Currently, developers who are applying this Internet-oriented approach need to have solid understanding about specific platforms and web technologies. In order to alleviate this development process, this research proposes a Resource-Oriented and Ontology-Driven Development (ROOD) methodology based on the Model Driven Architecture (MDA). This methodology aims at enabling the development of smart spaces through a set of modeling tools and semantic technologies that support the definition of the smart space and the automatic generation of code at hardware level. ROOD feasibility is demonstrated by building an adaptive health monitoring service for a Smart Gym.

  4. Low-power coprocessor for Haar-like feature extraction with pixel-based pipelined architecture

    NASA Astrophysics Data System (ADS)

    Luo, Aiwen; An, Fengwei; Fujita, Yuki; Zhang, Xiangyu; Chen, Lei; Jürgen Mattausch, Hans

    2017-04-01

    Intelligent analysis of image and video data requires image-feature extraction as an important processing capability for machine-vision realization. A coprocessor with pixel-based pipeline (CFEPP) architecture is developed for real-time Haar-like cell-based feature extraction. Synchronization with the image sensor’s pixel frequency and immediate usage of each input pixel for the feature-construction process avoids the dependence on memory-intensive conventional strategies like integral-image construction or frame buffers. One 180 nm CMOS prototype can extract the 1680-dimensional Haar-like feature vectors, applied in the speeded up robust features (SURF) scheme, using an on-chip memory of only 96 kb (kilobit). Additionally, a low power dissipation of only 43.45 mW at 1.8 V supply voltage is achieved during VGA video procession at 120 MHz frequency with more than 325 fps. The Haar-like feature-extraction coprocessor is further evaluated by the practical application of vehicle recognition, achieving the expected high accuracy which is comparable to previous work.

  5. Optimizing transformations of stencil operations for parallel cache-based architectures

    SciTech Connect

    Bassetti, F.; Davis, K.

    1999-06-28

    This paper describes a new technique for optimizing serial and parallel stencil- and stencil-like operations for cache-based architectures. This technique takes advantage of the semantic knowledge implicity in stencil-like computations. The technique is implemented as a source-to-source program transformation; because of its specificity it could not be expected of a conventional compiler. Empirical results demonstrate a uniform factor of two speedup. The experiments clearly show the benefits of this technique to be a consequence, as intended, of the reduction in cache misses. The test codes are based on a 5-point stencil obtained by the discretization of the Poisson equation and applied to a two-dimensional uniform grid using the Jacobi method as an iterative solver. Results are presented for a 1-D tiling for a single processor, and in parallel using 1-D data partition. For the parallel case both blocking and non-blocking communication are tested. The same scheme of experiments has bee n performed for the 2-D tiling case. However, for the parallel case the 2-D partitioning is not discussed here, so the parallel case handled for 2-D is 2-D tiling with 1-D data partitioning.

  6. Simulink-Based Simulation Architecture for Evaluating Controls for Aerospace Vehicles (SAREC-ASV)

    NASA Technical Reports Server (NTRS)

    Christhilf, David m.; Bacon, Barton J.

    2006-01-01

    The Simulation Architecture for Evaluating Controls for Aerospace Vehicles (SAREC-ASV) is a Simulink-based approach to providing an engineering quality desktop simulation capability for finding trim solutions, extracting linear models for vehicle analysis and control law development, and generating open-loop and closed-loop time history responses for control system evaluation. It represents a useful level of maturity rather than a finished product. The layout is hierarchical and supports concurrent component development and validation, with support from the Concurrent Versions System (CVS) software management tool. Real Time Workshop (RTW) is used to generate pre-compiled code for substantial component modules, and templates permit switching seamlessly between original Simulink and code compiled for various platforms. Two previous limitations are addressed. Turn around time for incorporating tabular model components was improved through auto-generation of required Simulink diagrams based on data received in XML format. The layout was modified to exploit a Simulink "compile once, evaluate multiple times" capability for zero elapsed time for use in trimming and linearizing. Trim is achieved through a Graphical User Interface (GUI) with a narrow, script definable interface to the vehicle model which facilitates incorporating new models.

  7. The Human Brainnetome Atlas: A New Brain Atlas Based on Connectional Architecture

    PubMed Central

    Fan, Lingzhong; Li, Hai; Zhuo, Junjie; Zhang, Yu; Wang, Jiaojian; Chen, Liangfu; Yang, Zhengyi; Chu, Congying; Xie, Sangma; Laird, Angela R.; Fox, Peter T.; Eickhoff, Simon B.; Yu, Chunshui; Jiang, Tianzi

    2016-01-01

    The human brain atlases that allow correlating brain anatomy with psychological and cognitive functions are in transition from ex vivo histology-based printed atlases to digital brain maps providing multimodal in vivo information. Many current human brain atlases cover only specific structures, lack fine-grained parcellations, and fail to provide functionally important connectivity information. Using noninvasive multimodal neuroimaging techniques, we designed a connectivity-based parcellation framework that identifies the subdivisions of the entire human brain, revealing the in vivo connectivity architecture. The resulting human Brainnetome Atlas, with 210 cortical and 36 subcortical subregions, provides a fine-grained, cross-validated atlas and contains information on both anatomical and functional connections. Additionally, we further mapped the delineated structures to mental processes by reference to the BrainMap database. It thus provides an objective and stable starting point from which to explore the complex relationships between structure, connectivity, and function, and eventually improves understanding of how the human brain works. The human Brainnetome Atlas will be made freely available for download at http://atlas.brainnetome.org, so that whole brain parcellations, connections, and functional data will be readily available for researchers to use in their investigations into healthy and pathological states. PMID:27230218

  8. Lightweight Filter Architecture for Energy Efficient Mobile Vehicle Localization Based on a Distributed Acoustic Sensor Network

    PubMed Central

    Kim, Keonwook

    2013-01-01

    The generic properties of an acoustic signal provide numerous benefits for localization by applying energy-based methods over a deployed wireless sensor network (WSN). However, the signal generated by a stationary target utilizes a significant amount of bandwidth and power in the system without providing further position information. For vehicle localization, this paper proposes a novel proximity velocity vector estimator (PVVE) node architecture in order to capture the energy from a moving vehicle and reject the signal from motionless automobiles around the WSN node. A cascade structure between analog envelope detector and digital exponential smoothing filter presents the velocity vector-sensitive output with low analog circuit and digital computation complexity. The optimal parameters in the exponential smoothing filter are obtained by analytical and mathematical methods for maximum variation over the vehicle speed. For stationary targets, the derived simulation based on the acoustic field parameters demonstrates that the system significantly reduces the communication requirements with low complexity and can be expected to extend the operation time considerably. PMID:23979482

  9. Compute unified device architecture (CUDA)-based parallelization of WRF Kessler cloud microphysics scheme

    NASA Astrophysics Data System (ADS)

    Mielikainen, Jarno; Huang, Bormin; Wang, Jun; Allen Huang, H.-L.; Goldberg, Mitchell D.

    2013-03-01

    In recent years, graphics processing units (GPUs) have emerged as a low-cost, low-power and a very high performance alternative to conventional central processing units (CPUs). The latest GPUs offer a speedup of two-to-three orders of magnitude over CPU for various science and engineering applications. The Weather Research and Forecasting (WRF) model is the latest-generation numerical weather prediction model. It has been designed to serve both operational forecasting and atmospheric research needs. It proves useful for a broad spectrum of applications for domain scales ranging from meters to hundreds of kilometers. WRF computes an approximate solution to the differential equations which govern the air motion of the whole atmosphere. Kessler microphysics module in WRF is a simple warm cloud scheme that includes water vapor, cloud water and rain. Microphysics processes which are modeled are rain production, fall and evaporation. The accretion and auto-conversion of cloud water processes are also included along with the production of cloud water from condensation. In this paper, we develop an efficient WRF Kessler microphysics scheme which runs on Graphics Processing Units (GPUs) using the NVIDIA Compute Unified Device Architecture (CUDA). The GPU-based implementation of Kessler microphysics scheme achieves a significant speedup of 70× over its CPU based single-threaded counterpart. When a 4 GPU system is used, we achieve an overall speedup of 132× as compared to the single thread CPU version.

  10. Implementation of an embedded image-based tracker in a distributed architecture

    NASA Astrophysics Data System (ADS)

    Schacht, Julie R.; Stephan, Larisa

    2002-07-01

    A major purpose of targeting systems is to ease operator workload by keeping the line of sight (LOS) pointed on a designated target. Our airborne electro-optic targeting system uses the latest technology to accomplish this end. If the latitude, longitude and altitude (geo-position) of a stationary ground target are known in advance, this system can use the aircraft's GPS-aided inertial navigation system to keep the LOS pointed at the target. If the operator wants to point at a target whose geo-position is unknown, this system can compute latitude, longitude and altitude using LOS attitude and range. The role of the image-based tracker in this system is to track airborne or moving ground targets and to compensate for drift and other limitations of geo-point for stationary ground targets. The algorithms implemented in our targeting system are not only processing intensive, but also diverse, incorporating a variety of information from numerous sources in order to provide the operator with the best LOS control solution for a given scenario. This, balanced against the low latency requirements of a real-time control system, has resulted in a software design that spans four separate processor boards. We present the implementation of a successful real-time embedded image-based tracker on a distributed architecture.

  11. Architecture for a Web-based clinical information system that keeps the design open and the access closed.

    PubMed

    Cimino, J J; Sengupta, S; Clayton, P D; Patel, V L; Kushniruk, A; Huang, X

    1998-01-01

    We are developing the Patient Clinical Information System (PatCIS) project at Columbia-Presbyterian Medical Center to provide patients with access to health information, including their own medical records (permitting them to contribute selected aspects to the record), educational materials and automated decision support. The architecture of the system allows for multiple, independent components which make use of central services for managing security and usage logging functions. The design accommodates a variety of data entry, data display and decision support tools and provides facilities for tracking system usage and questionnaires. The user interface minimizes hypertext-related disorientation and cognitive overload; our success in this regard is the subject of on-going evaluation.

  12. A Data Base for Curriculum Design in Medical Ethics.

    ERIC Educational Resources Information Center

    Tiberius, Richard G.; Cleave-Hogg, Doreen

    1984-01-01

    A study to provide information about medical students' prior knowledge of and attitudes toward medical ethics is reported. A questionnaire was administered to 845 entering medical students at the University of Toronto. The results support the need for a course that requires thinking rather than rote memory. (Author/MLW)

  13. A WPS Based Architecture for Climate Data Analytic Services (CDAS) at NASA

    NASA Astrophysics Data System (ADS)

    Maxwell, T. P.; McInerney, M.; Duffy, D.; Carriere, L.; Potter, G. L.; Doutriaux, C.

    2015-12-01

    Faced with unprecedented growth in the Big Data domain of climate science, NASA has developed the Climate Data Analytic Services (CDAS) framework. This framework enables scientists to execute trusted and tested analysis operations in a high performance environment close to the massive data stores at NASA. The data is accessed in standard (NetCDF, HDF, etc.) formats in a POSIX file system and processed using trusted climate data analysis tools (ESMF, CDAT, NCO, etc.). The framework is structured as a set of interacting modules allowing maximal flexibility in deployment choices. The current set of module managers include: Staging Manager: Runs the computation locally on the WPS server or remotely using tools such as celery or SLURM. Compute Engine Manager: Runs the computation serially or distributed over nodes using a parallelization framework such as celery or spark. Decomposition Manger: Manages strategies for distributing the data over nodes. Data Manager: Handles the import of domain data from long term storage and manages the in-memory and disk-based caching architectures. Kernel manager: A kernel is an encapsulated computational unit which executes a processor's compute task. Each kernel is implemented in python exploiting existing analysis packages (e.g. CDAT) and is compatible with all CDAS compute engines and decompositions. CDAS services are accessed via a WPS API being developed in collaboration with the ESGF Compute Working Team to support server-side analytics for ESGF. The API can be executed using either direct web service calls, a python script or application, or a javascript-based web application. Client packages in python or javascript contain everything needed to make CDAS requests. The CDAS architecture brings together the tools, data storage, and high-performance computing required for timely analysis of large-scale data sets, where the data resides, to ultimately produce societal benefits. It is is currently deployed at NASA in support of the

  14. Architecture for Knowledge-Based and Federated Search of Online Clinical Evidence

    PubMed Central

    Walther, Martin; Nguyen, Ken; Lovell, Nigel H

    2005-01-01

    Background It is increasingly difficult for clinicians to keep up-to-date with the rapidly growing biomedical literature. Online evidence retrieval methods are now seen as a core tool to support evidence-based health practice. However, standard search engine technology is not designed to manage the many different types of evidence sources that are available or to handle the very different information needs of various clinical groups, who often work in widely different settings. Objectives The objectives of this paper are (1) to describe the design considerations and system architecture of a wrapper-mediator approach to federate search system design, including the use of knowledge-based, meta-search filters, and (2) to analyze the implications of system design choices on performance measurements. Methods A trial was performed to evaluate the technical performance of a federated evidence retrieval system, which provided access to eight distinct online resources, including e-journals, PubMed, and electronic guidelines. The Quick Clinical system architecture utilized a universal query language to reformulate queries internally and utilized meta-search filters to optimize search strategies across resources. We recruited 227 family physicians from across Australia who used the system to retrieve evidence in a routine clinical setting over a 4-week period. The total search time for a query was recorded, along with the duration of individual queries sent to different online resources. Results Clinicians performed 1662 searches over the trial. The average search duration was 4.9 ± 3.2 s (N = 1662 searches). Mean search duration to the individual sources was between 0.05 s and 4.55 s. Average system time (ie, system overhead) was 0.12 s. Conclusions The relatively small system overhead compared to the average time it takes to perform a search for an individual source shows that the system achieves a good trade-off between performance and reliability. Furthermore, despite

  15. Feasibility of performing space surveillance tasks with a proposed space-based optical architecture

    NASA Astrophysics Data System (ADS)

    Flohrer, Tim; Krag, Holger; Klinkrad, Heiner; Schildknecht, Thomas

    Under ESA contract an industrial consortium including Aboa Space Research Oy (ASRO), the Astronomical Institute of the University of Bern (AIUB), and the Dutch National Aerospace Laboratory (NLR), proposed the observation concept, developed a suitable sensor architecture, and assessed the performance of a space-based optical (SBO) telescope in 2005. The goal of the SBO instrumentation was to analyse how the existing knowledge gap in the space debris population in the millimetre and centimetre regime may be closed by means of a passive op-tical instrument. SBO was requested to provide statistical information on the space debris population, in terms of number of objects and size distribution. The SBO was considered to be a cost-efficient instrumentation of 20 cm aperture and 6 deg field-of-view with flexible integration requirements. It should be possible to integrate the SBO easily as a secondary payload on satellites launched into low-Earth orbits (LEO), or into geostationary orbit (GEO). Thus the selected mission concept only allowed for fix-mounted telescopes, and the pointing direction could be requested freely. It was shown in the performance analysis that the statistical information on small-sized space debris can only be collected if the observation ranges are comparatively small. Two of the most promising concepts were to observe objects in LEO from a sensor placed into a sun-synchronous LEO, while objects in GEO should be observed from a GEO satellite. Since 2007 ESA focuses space surveillance and tracking activities in the Space Situational Awareness (SSA) preparatory program. Ground-based radars and optical telescopes are stud-ied for the build-up and to maintenance of a catalogue of objects. In this paper we analyse how the SBO architecture could contribute to the space surveillance tasks survey and tracking. We assume that the SBO instrumentation is placed into a circular sun-synchronous orbit at 800 km altitude. We discuss the observation conditions of

  16. Improving Workplace-Based Learning for Undergraduate Medical Students.

    PubMed

    Sajjad, Madiha; Mahboob, Usman

    2015-01-01

    Workplace-based learning is considered as one of the most effective way of translating medical theory into clinical practice. Although employed traditionally at postgraduate level, this strategy can be used in undergraduate students coming for clerkships in clinical departments. There are many challenges to workplace learning such as, unfavorable physical environment, lack of interest by clinical staff and teachers, and lack of student motivation. Clinical teachers can help bridge this gap and improve workplace learning through individual and collaborative team effort. Knowledge of various educational theories and principles and their application at workplace can enhance student learning and motivation, for which faculty development is much needed. Different teaching and learning activities can be used and tailored according to the clinical setting. Active reflection by students and constructive feedback from the clinicians forms the backbone of effective workplace learning.

  17. Problem-based learning in medical school: A student's perspective.

    PubMed

    Chang, Bliss J

    2016-12-01

    Problem-based learning (PBL) has been a concept in existence for decades yet its implementation in medical student education is limited. Considering the nature of a physician's work, PBL is a logical step towards developing students' abilities to synthesize and integrate foundational concepts into clinical medicine. Harvard's recently redesigned Pathways curriculum has shifted almost exclusively towards PBL in its one-year preclinical curriculum. This piece provides my thoughts, both derived from my own reflections as well as conversations and observations of my peers, on the effectiveness, advantages, and disadvantages of a PBL curriculum. All in all, the feelings of my peers and I regarding PBL has been overwhelmingly positive despite potential areas of improvement and continued fine-tuning.

  18. A Sustainable Architecture for Lunar Resource Prospecting from an EML-based Exploration Platform

    NASA Astrophysics Data System (ADS)

    Klaus, K.; Post, K.; Lawrence, S. J.

    2012-12-01

    Introduction - We present a point of departure architecture for prospecting for Lunar Resources from an Exploration Platform at the Earth - Moon Lagrange points. Included in our study are launch vehicle, cis-lunar transportation architecture, habitat requirements and utilization, lander/rover concepts and sample return. Different transfer design techniques can be explored by mission designers, testing various propulsive systems, maneuvers, rendezvous, and other in-space and surface operations. Understanding the availability of high and low energy trajectory transfer options opens up the possibility of exploring the human and logistics support mission design space and deriving solutions never before contemplated. For sample return missions from the lunar surface, low-energy transfers could be utilized between EML platform and the surface as well as return of samples to EML-based spacecraft. Human Habitation at the Exploration Platform - Telerobotic and telepresence capabilities are considered by the agency to be "grand challenges" for space technology. While human visits to the lunar surface provide optimal opportunities for field geologic exploration, on-orbit telerobotics may provide attractive early opportunities for geologic exploration, resource prospecting, and other precursor activities in advance of human exploration campaigns and ISRU processing. The Exploration Platform provides a perfect port for a small lander which could be refueled and used for multiple missions including sample return. The EVA and robotic capabilities of the EML Exploration Platform allow the lander to be serviced both internally and externally, based on operational requirements. The placement of the platform at an EML point allows the lander to access any site on the lunar surface, thus providing the global lunar surface access that is commonly understood to be required in order to enable a robust lunar exploration program. Designing the sample return lander for low

  19. A Secure ECC-based RFID Mutual Authentication Protocol to Enhance Patient Medication Safety.

    PubMed

    Jin, Chunhua; Xu, Chunxiang; Zhang, Xiaojun; Li, Fagen

    2016-01-01

    Patient medication safety is an important issue in patient medication systems. In order to prevent medication errors, integrating Radio Frequency Identification (RFID) technology into automated patient medication systems is required in hospitals. Based on RFID technology, such systems can provide medical evidence for patients' prescriptions and medicine doses, etc. Due to the mutual authentication between the medication server and the tag, RFID authentication scheme is the best choice for automated patient medication systems. In this paper, we present a RFID mutual authentication scheme based on elliptic curve cryptography (ECC) to enhance patient medication safety. Our scheme can achieve security requirements and overcome various attacks existing in other schemes. In addition, our scheme has better performance in terms of computational cost and communication overhead. Therefore, the proposed scheme is well suitable for patient medication systems.

  20. Integrating a modern knowledge-based system architecture with a legacy VA database: the ATHENA and EON projects at Stanford.

    PubMed

    Advani, A; Tu, S; O'Connor, M; Coleman, R; Goldstein, M K; Musen, M

    1999-01-01

    We present a methodology and database mediator tool for integrating modern knowledge-based systems, such as the Stanford EON architecture for automated guideline-based decision-support, with legacy databases, such as the Veterans Health Information Systems & Technology Architecture (VISTA) systems, which are used nation-wide. Specifically, we discuss designs for database integration in ATHENA, a system for hypertension care based on EON, at the VA Palo Alto Health Care System. We describe a new database mediator that affords the EON system both physical and logical data independence from the legacy VA database. We found that to achieve our design goals, the mediator requires two separate mapping levels and must itself involve a knowledge-based component.

  1. The P-Mesh: A Commodity-based Scalable Network Architecture for Clusters

    NASA Technical Reports Server (NTRS)

    Nitzberg, Bill; Kuszmaul, Chris; Stockdale, Ian; Becker, Jeff; Jiang, John; Wong, Parkson; Tweten, David (Technical Monitor)

    1998-01-01

    We designed a new network architecture, the P-Mesh which combines the scalability and fault resilience of a torus with the performance of a switch. We compare the scalability, performance, and cost of the hub, switch, torus, tree, and P-Mesh architectures. The latter three are capable of scaling to thousands of nodes, however, the torus has severe performance limitations with that many processors. The tree and P-Mesh have similar latency, bandwidth, and bisection bandwidth, but the P-Mesh outperforms the switch architecture (a lower bound for tree performance) on 16-node NAB Parallel Benchmark tests by up to 23%, and costs 40% less. Further, the P-Mesh has better fault resilience characteristics. The P-Mesh architecture trades increased management overhead for lower cost, and is a good bridging technology while the price of tree uplinks is expensive.

  2. Medical Image Fusion Based on Feature Extraction and Sparse Representation

    PubMed Central

    Wei, Gao; Zongxi, Song

    2017-01-01

    As a novel multiscale geometric analysis tool, sparse representation has shown many advantages over the conventional image representation methods. However, the standard sparse representation does not take intrinsic structure and its time complexity into consideration. In this paper, a new fusion mechanism for multimodal medical images based on sparse representation and decision map is proposed to deal with these problems simultaneously. Three decision maps are designed including structure information map (SM) and energy information map (EM) as well as structure and energy map (SEM) to make the results reserve more energy and edge information. SM contains the local structure feature captured by the Laplacian of a Gaussian (LOG) and EM contains the energy and energy distribution feature detected by the mean square deviation. The decision map is added to the normal sparse representation based method to improve the speed of the algorithm. Proposed approach also improves the quality of the fused results by enhancing the contrast and reserving more structure and energy information from the source images. The experiment results of 36 groups of CT/MR, MR-T1/MR-T2, and CT/PET images demonstrate that the method based on SR and SEM outperforms five state-of-the-art methods. PMID:28321246

  3. Usalpharma: a cloud-based architecture to support quality assurance training processes in health area using virtual worlds.

    PubMed

    García-Peñalvo, Francisco J; Cruz-Benito, Juan; Maderuelo, Cristina; Pérez-Blanco, Jonás Samuel; Martín-Suárez, Ana

    2014-01-01

    This paper discusses how cloud-based architectures can extend and enhance the functionality of the training environments based on virtual worlds and how, from this cloud perspective, we can provide support to analysis of training processes in the area of health, specifically in the field of training processes in quality assurance for pharmaceutical laboratories, presenting a tool for data retrieval and analysis that allows facing the knowledge discovery in the happenings inside the virtual worlds.

  4. All-optical cross-bar network architecture using TOAD based interferometric switch and designing of reconfigurable logic unit

    NASA Astrophysics Data System (ADS)

    Chattopadhyay, Tanay

    2011-12-01

    The design of all-optical 2 × 2 Terahertz Optical Asymmetric Demultiplexer (TOAD) based interferometric switch is proposed and described in this manuscript. Numerical simulation has been done to achieve the performance of the switch. Using this 2 × 2 TOAD based switch, cross-bar network architecture is designed. A reconfigurable logic unit is also proposed in this manuscript, which can perform 16-Boolean logical operations.

  5. Usalpharma: A Cloud-Based Architecture to Support Quality Assurance Training Processes in Health Area Using Virtual Worlds

    PubMed Central

    García-Peñalvo, Francisco J.; Pérez-Blanco, Jonás Samuel; Martín-Suárez, Ana

    2014-01-01

    This paper discusses how cloud-based architectures can extend and enhance the functionality of the training environments based on virtual worlds and how, from this cloud perspective, we can provide support to analysis of training processes in the area of health, specifically in the field of training processes in quality assurance for pharmaceutical laboratories, presenting a tool for data retrieval and analysis that allows facing the knowledge discovery in the happenings inside the virtual worlds. PMID:24778593

  6. Architectural Blueprint for Plate Boundary Observatories based on interoperable Data Management Platforms

    NASA Astrophysics Data System (ADS)

    Kerschke, D. I.; Häner, R.; Schurr, B.; Oncken, O.; Wächter, J.

    2014-12-01

    Interoperable data management platforms play an increasing role in the advancement of knowledge and technology in many scientific disciplines. Through high quality services they support the establishment of efficient and innovative research environments. Well-designed research environments can facilitate the sustainable utilization, exchange, and re-use of scientific data and functionality by using standardized community models. Together with innovative 3D/4D visualization, these concepts provide added value in improving scientific knowledge-gain, even across the boundaries of disciplines. A project benefiting from the added value is the Integrated Plate boundary Observatory in Chile (IPOC). IPOC is a European-South American network to study earthquakes and deformation at the Chilean continental margin and to monitor the plate boundary system for capturing an anticipated great earthquake in a seismic gap. In contrast to conventional observatories that monitor individual signals only, IPOC captures a large range of different processes through various observation methods (e.g., seismographs, GPS, magneto-telluric sensors, creep-meter, accelerometer, InSAR). For IPOC a conceptual design has been devised that comprises an architectural blueprint for a data management platform based on common and standardized data models, protocols, and encodings as well as on an exclusive use of Free and Open Source Software (FOSS) including visualization components. Following the principles of event-driven service-oriented architectures, the design enables novel processes by sharing and re-using functionality and information on the basis of innovative data mining and data fusion technologies. This platform can help to improve the understanding of the physical processes underlying plate deformations as well as the natural hazards induced by them. Through the use of standards, this blueprint can not only be facilitated for other plate observing systems (e.g., the European Plate

  7. Industry Standard Notation for Architecture-Centric Model-Based Engineering

    DTIC Science & Technology

    2010-01-20

    Bruce Lewis (AMRDEC SED) served as subcommittee chair, with Peter Feiler (SEI) as technical lead and author of the language. AADL incorporates concepts...underlying runtime system [ Feiler 09]. A number of recent studies have identified this problem and recommended a paradigm shift towards architecture-centric...AVSI 09] Feiler P. H., Hansson J., de Niz D., & Wrage L. System Architecture Virtual Integration: An Industrial Case Study (CMU/SEI-2009-TR-017

  8. Computer aided diagnosis based on medical image processing and artificial intelligence methods

    NASA Astrophysics Data System (ADS)

    Stoitsis, John; Valavanis, Ioannis; Mougiakakou, Stavroula G.; Golemati, Spyretta; Nikita, Alexandra; Nikita, Konstantina S.

    2006-12-01

    Advances in imaging technology and computer science have greatly enhanced interpretation of medical images, and contributed to early diagnosis. The typical architecture of a Computer Aided Diagnosis (CAD) system includes image pre-processing, definition of region(s) of interest, features extraction and selection, and classification. In this paper, the principles of CAD systems design and development are demonstrated by means of two examples. The first one focuses on the differentiation between symptomatic and asymptomatic carotid atheromatous plaques. For each plaque, a vector of texture and motion features was estimated, which was then reduced to the most robust ones by means of ANalysis of VAriance (ANOVA). Using fuzzy c-means, the features were then clustered into two classes. Clustering performances of 74%, 79%, and 84% were achieved for texture only, motion only, and combinations of texture and motion features, respectively. The second CAD system presented in this paper supports the diagnosis of focal liver lesions and is able to characterize liver tissue from Computed Tomography (CT) images as normal, hepatic cyst, hemangioma, and hepatocellular carcinoma. Five texture feature sets were extracted for each lesion, while a genetic algorithm based feature selection method was applied to identify the most robust features. The selected feature set was fed into an ensemble of neural network classifiers. The achieved classification performance was 100%, 93.75% and 90.63% in the training, validation and testing set, respectively. It is concluded that computerized analysis of medical images in combination with artificial intelligence can be used in clinical practice and may contribute to more efficient diagnosis.

  9. Status and progress of the novel photon detectors based on THGEM and hybrid MPGD architectures

    NASA Astrophysics Data System (ADS)

    Alexeev, M.; Birsa, R.; Bradamante, F.; Bressan, A.; Büchele, M.; Chiosso, M.; Ciliberti, P.; Dalla Torre, S.; Dasgupta, S.; Denisov, O.; Duic, V.; Finger, M.; Finger, M.; Fischer, H.; Giorgi, M.; Gobbo, B.; Gregori, M.; Herrmann, F.; Königsmann, K.; Levorato, S.; Maggiora, A.; Martin, A.; Menon, G.; Novakova, K.; Novy, J.; Panzieri, D.; Pereira, F. A.; Santos, C. A.; Sbrizzai, G.; Schiavon, P.; Schopferer, S.; Slunecka, M.; Sozzi, F.; Steiger, L.; Sulc, M.; Takekawa, S.; Tessarotto, F.; Veloso, J. F. C. A.

    2014-12-01

    We are developing large size THick GEM (THGEM)-based detectors of single photons, mainly meant for Cherenkov imaging applications. The R&D programme includes the complete characterisation of the THGEM electron multipliers, the study of the aspects related to the detection of single photons and the engineering towards large size detector prototypes. Our most recent achievements include dedicated studies concerning the ion backflow to the photocathode; relevant progress in the engineering aspects, in particularly related to the production of large-size THGEMs, where the strict correlation between the local gain-value and the local thickness-value has been demonstrated and a 300×300 mm2 active area detector has been successfully operated at the CERN PS T10 test beam; the introduction of a new hybrid detector architecture, offering promising performance, which is formed by a THGEM layer which acts both as photocathode and pre-amplification device, followed by a MICROMEGAS (MM) multiplication stage. We report about the general status of the R&D programme and, in detail, about the recent progress.

  10. Compact SPAD-Based Pixel Architectures for Time-Resolved Image Sensors

    PubMed Central

    Perenzoni, Matteo; Pancheri, Lucio; Stoppa, David

    2016-01-01

    This paper reviews the state of the art of single-photon avalanche diode (SPAD) image sensors for time-resolved imaging. The focus of the paper is on pixel architectures featuring small pixel size (<25 μm) and high fill factor (>20%) as a key enabling technology for the successful implementation of high spatial resolution SPAD-based image sensors. A summary of the main CMOS SPAD implementations, their characteristics and integration challenges, is provided from the perspective of targeting large pixel arrays, where one of the key drivers is the spatial uniformity. The main analog techniques aimed at time-gated photon counting and photon timestamping suitable for compact and low-power pixels are critically discussed. The main features of these solutions are the adoption of analog counting techniques and time-to-analog conversion, in NMOS-only pixels. Reliable quantum-limited single-photon counting, self-referenced analog-to-digital conversion, time gating down to 0.75 ns and timestamping with 368 ps jitter are achieved. PMID:27223284

  11. Self assembled pseudo double helix architecture and anion sensing behavior of a coumarin based ICT probe

    NASA Astrophysics Data System (ADS)

    Upadhyay, K. K.; Mishra, Rakesh K.; Kumar, Ajit; Zhao, Jianzhang; Prasad, Rajendra

    2010-01-01

    The X-ray diffraction (XRD) studies of a coumarin based hydrazone (receptor 1) have revealed self assembled pseudo double helix architecture involving closed shell O---O interactions besides other supramolecular interactions. The receptor (1) an intramolecular charge transfer (ICT) probe detected acetate, benzoate and dihydrogenphosphate through naked-eye in DMSO. The 1:1 stoichiometry was confirmed for all the anions. The 1H NMR studies indicated classical and non-classical hydrogen bonding through -NH and Ar-H protons of the receptor, respectively, during recognition process of the acetate through receptor (1). The theoretical studies through density functional theory (DFT) using B3LYP exchange functional with the basis set 6-311G∗∗ supported the UV-vis and 1H NMR studies. The time dependent density functional theory (TDDFT) computations of UV-vis excitations for the receptor (1) and receptor-acetate complex agreed well with our experimental findings. The cyclic voltammetric studies also supported formation of receptor-acetate complex.

  12. Aligned Silk-Based 3D Architectures for Contact Guidance in Tissue Engineering

    PubMed Central

    Oliveira, A.L.; Sun, L.; Kim, H. J.; Hu, X.; Rice, W.; Kluge, J.; Reis, R. L.; Kaplan, D. L.

    2011-01-01

    An important challenge in the biomaterials field is to mimic the structure of functional tissues via cell and extracellular matrix (ECM) alignment and anisotropy. Toward this goal, silk-based scaffolds resembling bone lamellar structure were developed using a freeze-drying technique. The structure could be controlled directly by solute concentration and freezing parameters, resulting in lamellar scaffolds with regular morphology. Different post-treatments were investigated to induce water stability, such as methanol, water annealing and steam sterilization. The resulting structures exhibited significant differences in terms of morphological integrity, structure and mechanical properties. the lamellar thicknesses were around ~2,6 μm for the methanol treated scaffolds and ~5,8 μm for water-annealed. These values are in the range of the reported for human lamellar bone. Human bone marrow-derived mesenchymal stem cells (hMSCs) were seeded on these silk fibroin lamellar scaffolds and grown under osteogenic conditions to assess the effect of the microstructure on cell behaviour. Collagen in the newly deposited ECM, was found aligned along the lamellar architectures. In the case of methanol treated lamellar structures the hMSCs were able to migrate into the interior of the scaffolds producing a multilamellar hybrid construct. The present morphology constitutes a useful pattern onto which hMSCs cells attach and proliferate for guided formation of a highly oriented extracellular matrix. PMID:22202909

  13. Motion-sensor fusion-based gesture recognition and its VLSI architecture design for mobile devices

    NASA Astrophysics Data System (ADS)

    Zhu, Wenping; Liu, Leibo; Yin, Shouyi; Hu, Siqi; Tang, Eugene Y.; Wei, Shaojun

    2014-05-01

    With the rapid proliferation of smartphones and tablets, various embedded sensors are incorporated into these platforms to enable multimodal human-computer interfaces. Gesture recognition, as an intuitive interaction approach, has been extensively explored in the mobile computing community. However, most gesture recognition implementations by now are all user-dependent and only rely on accelerometer. In order to achieve competitive accuracy, users are required to hold the devices in predefined manner during the operation. In this paper, a high-accuracy human gesture recognition system is proposed based on multiple motion sensor fusion. Furthermore, to reduce the energy overhead resulted from frequent sensor sampling and data processing, a high energy-efficient VLSI architecture implemented on a Xilinx Virtex-5 FPGA board is also proposed. Compared with the pure software implementation, approximately 45 times speed-up is achieved while operating at 20 MHz. The experiments show that the average accuracy for 10 gestures achieves 93.98% for user-independent case and 96.14% for user-dependent case when subjects hold the device randomly during completing the specified gestures. Although a few percent lower than the conventional best result, it still provides competitive accuracy acceptable for practical usage. Most importantly, the proposed system allows users to hold the device randomly during operating the predefined gestures, which substantially enhances the user experience.

  14. Security Analysis of DTN Architecture and Bundle Protocol Specification for Space-Based Networks

    NASA Technical Reports Server (NTRS)

    Ivancic, William D.

    2009-01-01

    A Delay-Tolerant Network (DTN) Architecture (Request for Comment, RFC-4838) and Bundle Protocol Specification, RFC-5050, have been proposed for space and terrestrial networks. Additional security specifications have been provided via the Bundle Security Specification (currently a work in progress as an Internet Research Task Force internet-draft) and, for link-layer protocols applicable to Space networks, the Licklider Transport Protocol Security Extensions. This document provides a security analysis of the current DTN RFCs and proposed security related internet drafts with a focus on space-based communication networks, which is a rather restricted subset of DTN networks. Note, the original focus and motivation of DTN work was for the Interplanetary Internet . This document does not address general store-and-forward network overlays, just the current work being done by the Internet Research Task Force (IRTF) and the Consultative Committee for Space Data Systems (CCSDS) Space Internetworking Services Area (SIS) - DTN working group under the DTN and Bundle umbrellas. However, much of the analysis is relevant to general store-and-forward overlays.

  15. Reflective off-axis point-diffraction interferometer based on Michelson architecture

    NASA Astrophysics Data System (ADS)

    Bai, Hongyi; Guo, Lili; Zhong, Zhi; Shan, Mingguang; Zhang, Yabin

    2015-02-01

    A reflective off-axis point-diffraction interferometer based on Michelson architecture is built to measure static and dynamic quantitative phase in a single shot. The interferometer is constructed by a beam-splitter, a pinhole mirror, a reflective mirror and two lenses to build a 4f optical system. The pinhole mirror is used as a low-pass spatial filter to generate reference wave. By tilting the reflective mirror, a small angle is created between the object beam and the reference beam to enable an off-axis interferogram. To reconstruct an interferogram with a few fringes, Kreis Fourier method is used to recovery the specimen phase. Using a plano-convex cylinder lens and an evaporative alcohol drop as the specimens, experiments are run to verify the effectiveness and robustness with this interferometer. Experimental results show that this interferometer has not only simple setup and good anti-interference performance, but also good real-time ability, which makes it suitable for dynamic phase measurement.

  16. Implementation and design of a teleoperation system based on a VMEBUS/68020 pipelined architecture

    NASA Technical Reports Server (NTRS)

    Lee, Thomas S.

    1989-01-01

    A pipelined control design and architecture for a force-feedback teleoperation system that is being implemented at the Jet Propulsion Laboratory and which will be integrated with the autonomous portion of the testbed to achieve share control is described. At the local site, the operator sees real-time force/torque displays and moves two 6-degree of freedom (dof) force-reflecting hand-controllers as his hands feel the contact force/torques generated at the remote site where the robots interact with the environment. He also uses a graphical user menu to monitor robot states and specify system options. The teleoperation software is written in the C language and runs on MC68020-based processor boards in the VME chassis, which utilizes a real-time operating system; the hardware is configured to realize a four-stage pipeline configuration. The environment is very flexible, such that the system can easily be configured as a stand-alone facility for performing independent research in human factors, force control, and time-delayed systems.

  17. Architectural design of a ground-based deep-space optical reception antenna

    NASA Technical Reports Server (NTRS)

    Kerr, E. L.

    1989-01-01

    An architectural design of a ground-based antenna (telescope) for receiving optical communications from deep space is presented. Physical and optical parameters, and their effect on the performance and cost considerations, are described. The channel capacity of the antenna is 100 kbits/s from Saturn and 5 Mbits/s from Mars. A novel sunshade is designed to permit optical communication even when the deep-space laser source is as close to the sun as 12 deg. Inserts in the tubes of the sunshade permit operations at solar elongations as small as 6 or 3 deg. The Nd:YAG source laser and the Fraunhofer filter (a narrow-band predetection optical filter) are tuned to match the Doppler shifts of the source and background. A typical Saturn-to-earth data link can reduce its source power requirement from 8.2 W to 2 W of laser output by employing a Fraunhofer filter instead of a conventional multilayer dielectric filter.

  18. A confocal microscopy-based atlas of tissue architecture in the tapeworm Hymenolepis diminuta.

    PubMed

    Rozario, Tania; Newmark, Phillip A

    2015-11-01

    Tapeworms are pervasive and globally distributed parasites that infect millions of humans and livestock every year, and are the causative agents of two of the 17 neglected tropical diseases prioritized by the World Health Organization. Studies of tapeworm biology and pathology are often encumbered by the complex life cycles of disease-relevant tapeworm species that infect hosts such as foxes, dogs, cattle, pigs, and humans. Thus, studies of laboratory models can help overcome the practical, ethical, and cost-related difficulties faced by tapeworm parasitologists. The rat intestinal tapeworm Hymenolepis diminuta is easily reared in the laboratory and has the potential to enable modern molecular-based experiments that will greatly contribute to our understanding of multiple aspects of tapeworm biology, such as growth and reproduction. As part of our efforts to develop molecular tools for experiments on H. diminuta, we have characterized a battery of lectins, antibodies, and common stains that label different tapeworm tissues and organ structures. Using confocal microscopy, we have assembled an "atlas" of H. diminuta organ architecture that will be a useful resource for helminthologists. The methodologies we describe will facilitate characterization of loss-of-function perturbations using H. diminuta. This toolkit will enable a greater understanding of fundamental tapeworm biology that may elucidate new therapeutic targets toward the eradication of these parasites.

  19. VLSI design of an RSA encryption/decryption chip using systolic array based architecture

    NASA Astrophysics Data System (ADS)

    Sun, Chi-Chia; Lin, Bor-Shing; Jan, Gene Eu; Lin, Jheng-Yi

    2016-09-01

    This article presents the VLSI design of a configurable RSA public key cryptosystem supporting the 512-bit, 1024-bit and 2048-bit based on Montgomery algorithm achieving comparable clock cycles of current relevant works but with smaller die size. We use binary method for the modular exponentiation and adopt Montgomery algorithm for the modular multiplication to simplify computational complexity, which, together with the systolic array concept for electric circuit designs effectively, lower the die size. The main architecture of the chip consists of four functional blocks, namely input/output modules, registers module, arithmetic module and control module. We applied the concept of systolic array to design the RSA encryption/decryption chip by using VHDL hardware language and verified using the TSMC/CIC 0.35 m 1P4 M technology. The die area of the 2048-bit RSA chip without the DFT is 3.9 × 3.9 mm2 (4.58 × 4.58 mm2 with DFT). Its average baud rate can reach 10.84 kbps under a 100 MHz clock.

  20. A Data System Architecture for Measurement Based Systems: Precipitation Processing System

    NASA Technical Reports Server (NTRS)

    Stocker, Erich Franz

    2003-01-01

    NASA s Earth Science Enterprise (ESE) is changing focus from single satellite missions to measurement oriented programs. An example of this paradigm shift is the Global Precipitation Measurement (GPM) project. GPM is conceptualized as a rolling-wave of measurement possibilities all focused on the key precipitation parameter. In response to this shift to measurement programs and also integral to the ESE s new strategy for processing and management its data, a measurement based approach is also critical for data processing system that support measurement programs like GPM. This paper provides an overview of the paradigm shift from mission to measurement. It also presents a summary of the ESE s new strategy for its data systems. Building on this background the paper details the architectural, design and implementation aspects of the Precipitation Processing System (PPS). The PPS is an evolution of a single point system developed for the Tropical Rainfall Measurement Mission to a generic precipitation data system. The paper provides the context within which PPS will support the GPM program.

  1. Polyhomologation based on in situ generated boron-thexyl-silaboracyclic initiating sites: a novel strategy towards the synthesis of polyethylene-based complex architectures.

    PubMed

    Zhang, Zhen; Zhang, Hefeng; Gnanou, Yves; Hadjichristidis, Nikos

    2015-06-21

    A novel strategy, based on the in situ generated boron-thexyl-silaboracyclic initiating sites for the polyhomologation of dimethylsulfoxonium methylide, has been developed for the synthesis of complex polyethylene-based architectures. As examples, the synthesis of a 4-arm polyethylene star, three (polystyrene)(polyethylene)2 3-miktoarm stars and a PE-branched double graft copolymer is given.

  2. Advanced ESPI-based medical instruments for otolaryngology

    NASA Astrophysics Data System (ADS)

    Castracane, James; Conerty, M.; Cacace, Anthony T.; Gardner, Glendon M.; Miller, Mitchell B.; Parnes, Steven M.

    1993-05-01

    Optical fibers have long been used for visual inspection inside the human body for medical diagnoses and treatment. By making use of sophisticated optical interferometric and ultra- small imaging techniques, combined with automated image processing, it is possible to extract significantly increased information for more accurate medical diagnoses. With support from NIH under the SBIR program, we have been developing a range of such instruments. One of these supported by the NIDCD is capable of providing detailed spatial information on the vibratory response of the tympanic membrane (TM). This instrument involves the examination of the TM by means of high speed electronic speckle pattern interferometry (ESPI). This provides a real time view of the vibration patterns of the TM for clinical diagnosis. This Interferometric Otoscope consists of mode conserving fiber optics, miniature diode lasers and high speed solid state detector arrays. We present the current status of the research including holography and ESPI of TM models and excised temporal bone preparations. A second instrument, also developed with support from NIDCD, is for application to the larynx. This system is also ESPI based but will incorporate features for direct vocal cord (VC) examination. By careful examination of the vibratory response of the VC during phonation, the characteristics of the mucosal wave may be examined. Adynamic regions of the cords can signal the start of lesions or cysts. Results of surgery can be evaluated in a quantitative manner. The design of a clinical prototype and preliminary electro-optic experiments on excised larynges and VC models will be presented.

  3. Intelligent technique for knowledge reuse of dental medical records based on case-based reasoning.

    PubMed

    Gu, Dong-Xiao; Liang, Chang-Yong; Li, Xing-Guo; Yang, Shan-Lin; Zhang, Pei

    2010-04-01

    With the rapid development of both information technology and the management of modern medical regulation, the generation of medical records tends to be increasingly intelligent. In this paper, Case-Based Reasoning is applied to the process of generating records of dental cases. Based on the analysis of the features of dental records, a case base is constructed. A mixed case retrieval method (FAIES) is proposed for the knowledge reuse of dental records by adopting Fuzzy Mathematics, which improves similarity algorithm based on Euclidian-Lagrangian Distance, and PULL & PUSH weight adjustment strategy. Finally, an intelligent system of dental cases generation (CBR-DENT) is constructed. The effectiveness of the system, the efficiency of the retrieval method, the extent of adaptation and the adaptation efficiency are tested using the constructed case base. It is demonstrated that FAIES is very effective in terms of reducing the time of writing medical records and improving the efficiency and quality. FAIES is also proven to be an effective aid for diagnoses and provides a new idea for the management of medical records and its applications.

  4. Architecture For The Optimization Of A Machining Process In Real Time Through Rule-Based Expert System

    NASA Astrophysics Data System (ADS)

    Serrano, Rafael; González, Luis Carlos; Martín, Francisco Jesús

    2009-11-01

    Under the project SENSOR-IA which has had financial funding from the Order of Incentives to the Regional Technology Centers of the Counsil of Innovation, Science and Enterprise of Andalusia, an architecture for the optimization of a machining process in real time through rule-based expert system has been developed. The architecture consists of an acquisition system and sensor data processing engine (SATD) from an expert system (SE) rule-based which communicates with the SATD. The SE has been designed as an inference engine with an algorithm for effective action, using a modus ponens rule model of goal-oriented rules.The pilot test demonstrated that it is possible to govern in real time the machining process based on rules contained in a SE. The tests have been done with approximated rules. Future work includes an exhaustive collection of data with different tool materials and geometries in a database to extract more precise rules.

  5. Texture based feature extraction methods for content based medical image retrieval systems.

    PubMed

    Ergen, Burhan; Baykara, Muhammet

    2014-01-01

    The developments of content based image retrieval (CBIR) systems used for image archiving are continued and one of the important research topics. Although some studies have been presented general image achieving, proposed CBIR systems for archiving of medical images are not very efficient. In presented study, it is examined the retrieval efficiency rate of spatial methods used for feature extraction for medical image retrieval systems. The investigated algorithms in this study depend on gray level co-occurrence matrix (GLCM), gray level run length matrix (GLRLM), and Gabor wavelet accepted as spatial methods. In the experiments, the database is built including hundreds of medical images such as brain, lung, sinus, and bone. The results obtained in this study shows that queries based on statistics obtained from GLCM are satisfied. However, it is observed that Gabor Wavelet has been the most effective and accurate method.

  6. Rapid EHR development and implementation using web and cloud-based architecture in a large home health and hospice organization.

    PubMed

    Weaver, Charlotte A; Teenier, Pamela

    2014-01-01

    Health care organizations have long been limited to a small number of major vendors in their selection of an electronic health record (EHR) system in the national and international marketplace. These major EHR vendors have in common base systems that are decades old, are built in antiquated programming languages, use outdated server architecture, and are based on inflexible data models [1,2]. The option to upgrade their technology to keep pace with the power of new web-based architecture, programming tools and cloud servers is not easily undertaken due to large client bases, development costs and risk [3]. This paper presents the decade-long efforts of a large national provider of home health and hospice care to select an EHR product, failing that to build their own and failing that initiative to go back into the market in 2012. The decade time delay had allowed new technologies and more nimble vendors to enter the market. Partnering with a new start-up company doing web and cloud based architecture for the home health and hospice market, made it possible to build, test and implement an operational and point of care system in 264 home health locations across 40 states and three time zones in the United States. This option of "starting over" with the new web and cloud technologies may be posing a next generation of new EHR vendors that retells the Blackberry replacement by iPhone story in healthcare.

  7. Knowledge-based topographic feature extraction in medical images

    NASA Astrophysics Data System (ADS)

    Qian, JianZhong; Khair, Mohammad M.

    1995-08-01

    Diagnostic medical imaging often contains variations of patient anatomies, camera mispositioning, or other imperfect imaging condiitons. These variations contribute to uncertainty about shapes and boundaries of objects in images. As the results sometimes image features, such as traditional edges, may not be identified reliably and completely. We describe a knowledge based system that is able to reason about such uncertainties and use partial and locally ambiguous information to infer about shapes and lcoation of objects in an image. The system uses directional topographic features (DTFS), such as ridges and valleys, labeled from the underlying intensity surface to correlate to the intrinsic anatomical information. By using domain specific knowledge, the reasoning system can deduce significant anatomical landmarks based upon these DTFS, and can cope with uncertainties and fill in missing information. A succession of levels of representation for visual information and an active process of uncertain reasoning about this visual information are employed to realiably achieve the goal of image analysis. These landmarks can then be used in localization of anatomy of interest, image registration, or other clinical processing. The successful application of this system to a large set of planar cardiac images of nuclear medicine studies has demonstrated its efficiency and accuracy.

  8. Architectural Effects on Solution Self-Assembly of Poly(3-hexylthiophene)-Based Graft Copolymers.

    PubMed

    Kim, Youngkwon; Kim, Hyeong Jun; Kim, Jin-Seong; Hayward, Ryan C; Kim, Bumjoon J

    2017-01-25

    While solution assembly of conjugated block copolymers has been widely used to produce long 1-D nanowires (NWs), it remains a great challenge to provide a higher level of control over structure and function of the NWs. Herein, for the first time, we report the solution assembly of graft copolymers containing a conjugated polymer backbone in a selective solvent and demonstrate that their self-assembly behaviors can be manipulated by the molecular structures of the graft copolymers. A series of poly(3-hexylthiophene)-graft-poly(2-vinylpyridine) (P3HT-g-P2VP) copolymers was designed with two different architectural parameters: grafting fraction (fg) and molecular weight of P2VP chains (Mn,P2VP) on the P3HT backbone. Interestingly, crystallization of the P3HT-g-P2VP copolymers was systematically modulated by changes in fg and Mn,P2VP, thus allowing for control of the growth kinetics and curvatures of solution-assembled NWs. When Mn,P2VP (4.4 to 15.1 kg/mol) or fg (2.8 to 9.2%) of the P3HT-g-P2VP polymers was increased, the crystallinity of the copolymers was reduced significantly. Steric hindrance from the grafted P2VP chains apparently modified the growth of NWs, leading to shorter NWs with a greater degree of curvature for graft copolymers with more hindrance. Therefore, we envision that such conjugated chain-based graft copolymers can be versatile building blocks for producing NWs with controlled length and shape, which can be important for tailoring the optical and electrical properties of NW-based devices.

  9. Active on-demand service method based on event-driven architecture for geospatial data retrieval

    NASA Astrophysics Data System (ADS)

    Fan, Minghu; Fan, Hong; Chen, Nengcheng; Chen, Zeqiang; Du, Wu

    2013-07-01

    Timely on-demand access to geospatial data is necessary for environmental observation and disaster response. However, traditional service methods for acquiring geospatial data are inefficient and cumbersome, which is not beneficial for timely data acquisition. In these service methods, data are obtained and published by managers and are then left to users to discover and to retrieve them. To solve this problem, we propose an event-driven active on-demand data service method, for which a prototype based on sensor web technologies is demonstrated. First, we select a subset of observed properties as the attributes of an observation event of a data service system. Event-filtering technologies are then employed to find the data desired by users. Finally, the data that meet the subscription requirement are pushed to subscribers on time. The aims of the implementation of the method are to test the suitability of the observation and measurement (O&M) profile for Earth observation and OGC event pattern markup language (EML) specification. We determined the attributes of observation events according to the requirement of the data service and encoded observation event information using the OGC Observations and Measurements specification. We encoded the information under filtering conditions using the OGC Event Pattern Markup Language specification. We implemented a data service method that is based on event-driven architecture via a combination of some sensor web enablement services. Finally, we verified the feasibility of the method using MODIS data from the forest fires that occurred on February 7, 2009, in Victoria, Australia. The results show that the proposed method can achieve actively pushing the desired data to subscribers in the shortest possible time. O&M profiles for Earth observation and EML are suitable for the metadata encoding of observation events and the encoding of subscription information respectively. They match well for the data service in the system.

  10. Architectural concepts of Martian bases built: of domes, around greenhouses and into slopes -the human aspect and the technology

    NASA Astrophysics Data System (ADS)

    Kozicki, Janek; Kozicka, Joanna

    Human missions to Mars are a special kind of space missions due to their long duration. The human aspect of such missions becomes as important as the technological one. The need for a human friendly and comfortable habitat arises. Studies of human behavior in ICEs have shown that larger groups of people mean a lower occurrence of conflicts. However, for a larger crew a larger habitat has to be designed -a Martian base. The research deals with psychological, sociological and technological aspects influencing the architectural design of a Martian Base. Extreme conditions present on Mars demand a partic-ular approach to technological and architectural design. To reduce the cost of building a bigger habitat, low cost solutions have been inquired into. A series of analyses has been performed to identify the best architectural solutions for a Martian base. A review of existing technologies and extreme condition habitats (both terrestrial and extraterrestrial) has revealed solutions that are the most reliable and efficient ones. Additionally, innovative technologies have been analyzed in search of the best candidates for actual base construction. Low cost solutions have been prioritized in the process. An in-depth study of architectural problems inherent in the design of a Martian base has resulted in a number of guidelines for the architect. The main ones are introduced in this review. Based on them, several concepts have been drafted as examples of user-friendly and aesthetically pleasing habitats. They are discussed in the following order: habitats made of domes, those built around greenhouses and those situated in sloping terrain. One of them is presented in detail, including interior design.

  11. Model-based system-of-systems engineering for space-based command, control, communication, and information architecture design

    NASA Astrophysics Data System (ADS)

    Sindiy, Oleg V.

    This dissertation presents a model-based system-of-systems engineering (SoSE) approach as a design philosophy for architecting in system-of-systems (SoS) problems. SoS refers to a special class of systems in which numerous systems with operational and managerial independence interact to generate new capabilities that satisfy societal needs. Design decisions are more complicated in a SoS setting. A revised Process Model for SoSE is presented to support three phases in SoS architecting: defining the scope of the design problem, abstracting key descriptors and their interrelations in a conceptual model, and implementing computer-based simulations for architectural analyses. The Process Model enables improved decision support considering multiple SoS features and develops computational models capable of highlighting configurations of organizational, policy, financial, operational, and/or technical features. Further, processes for verification and validation of SoS models and simulations are also important due to potential impact on critical decision-making and, thus, are addressed. Two research questions frame the research efforts described in this dissertation. The first concerns how the four key sources of SoS complexity---heterogeneity of systems, connectivity structure, multi-layer interactions, and the evolutionary nature---influence the formulation of SoS models and simulations, trade space, and solution performance and structure evaluation metrics. The second question pertains to the implementation of SoSE architecting processes to inform decision-making for a subset of SoS problems concerning the design of information exchange services in space-based operations domain. These questions motivate and guide the dissertation's contributions. A formal methodology for drawing relationships within a multi-dimensional trade space, forming simulation case studies from applications of candidate architecture solutions to a campaign of notional mission use cases, and

  12. [Research on medical instrument information integration technology based on IHE PCD].

    PubMed

    Zheng, Jianli; Liao, Yun; Yang, Yongyong

    2014-06-01

    Integrating medical instruments with medical information systems becomes more and more important in healthcare industry. To make medical instruments without standard communication interface possess the capability of interoperating and sharing information with medical information systems, we developed a medical instrument integration gateway based on Integrating the Healthcare Enterprise Patient Care Device (IHE PCD) integration profiles in this research. The core component is an integration engine which is implemented according to integration profiles and Health Level Seven (HL7) messages defined in IHE PCD. Working with instrument specific Javascripts, the engine transforms medical instrument data into HL7 ORU message. This research enables medical instruments to interoperate and exchange medical data with information systems in a standardized way, and is valuable for medical instrument integration, especially for traditional instruments.

  13. A Community-Based Approach for Integrating Geriatrics and Gerontology into Undergraduate Medical Education

    ERIC Educational Resources Information Center

    Martinez, Iveris L.; Mora, Jorge Camilo

    2012-01-01

    Medical school accreditation requirements require educational opportunities in geriatrics. Twenty-six minimum graduating competencies in geriatrics have recently been identified for medical students. The authors describe how these competencies are being integrated into a new medical curriculum through coursework and community-based experiences.…

  14. Medical Students' Experiences with Addicted Patients: A Web-Based Survey

    ERIC Educational Resources Information Center

    Midmer, Deana; Kahan, Meldon; Wilson, Lynn

    2008-01-01

    Project CREATE was an initiative to strengthen undergraduate medical education in addictions. As part of a needs assessment, forty-six medical students at Ontario's five medical schools completed a bi-weekly, interactive web-based survey about addiction-related learning events. In all, 704 unique events were recorded, for an average of 16.7…

  15. An image based information system - Architecture for correlating satellite and topological data bases

    NASA Technical Reports Server (NTRS)

    Bryant, N. A.; Zobrist, A. L.

    1978-01-01

    The paper describes the development of an image based information system and its use to process a Landsat thematic map showing land use or land cover in conjunction with a census tract polygon file to produce a tabulation of land use acreages per census tract. The system permits the efficient cross-tabulation of two or more geo-coded data sets, thereby setting the stage for the practical implementation of models of diffusion processes or cellular transformation. Characteristics of geographic information systems are considered, and functional requirements, such as data management, geocoding, image data management, and data analysis are discussed. The system is described, and the potentialities of its use are examined.

  16. Race-based medical mistrust, medication beliefs and HIV treatment adherence: test of a mediation model in people living with HIV/AIDS.

    PubMed

    Kalichman, Seth C; Eaton, Lisa; Kalichman, Moira O; Grebler, Tama; Merely, Cynthia; Welles, Brandi

    2016-12-01

    Race-based medical mistrust significantly predicts non-adherence to antiretroviral therapy (ART) in people living with HIV. The current study builds on previous research that shows beliefs about medication necessity (i.e., "My medicines protect me from becoming worse") and concerns (i.e., "Having to take my medicines worries me") mediate the association between race-based medical mistrust and medication adherence. Racial and ethnic minority men and women living with HIV and receiving ART (N = 178) in a southern US city completed computerized measures of demographic and health characteristics, telephone interviews of race-based medical mistrust and medication beliefs, and unannounced phone-based pill counts for ART adherence. Multiple mediation modeling showed that medical mistrust is related to medication necessity and concerns beliefs and ART adherence. Furthermore, medication necessity beliefs predicted ART adherence. The indirect effect of medical mistrust on adherence through medication necessity beliefs was also significant. Results confirm that medication necessity beliefs, although not concerns beliefs, mediate the association between medical mistrust and ART adherence. Medication necessity beliefs offer a viable target for interventions to improve ART adherence in the context of mistrust that patients may have for medical providers and health care systems.

  17. Adaptive Software Architecture Based on Confident HCI for the Deployment of Sensitive Services in Smart Homes

    PubMed Central

    Vega-Barbas, Mario; Pau, Iván; Martín-Ruiz, María Luisa; Seoane, Fernando

    2015-01-01

    Smart spaces foster the development of natural and appropriate forms of human-computer interaction by taking advantage of home customization. The interaction potential of the Smart Home, which is a special type of smart space, is of particular interest in fields in which the acceptance of new technologies is limited and restrictive. The integration of smart home design patterns with sensitive solutions can increase user acceptance. In this paper, we present the main challenges that have been identified in the literature for the successful deployment of sensitive services (e.g., telemedicine and assistive services) in smart spaces and a software architecture that models the functionalities of a Smart Home platform that are required to maintain and support such sensitive services. This architecture emphasizes user interaction as a key concept to facilitate the acceptance of sensitive services by end-users and utilizes activity theory to support its innovative design. The application of activity theory to the architecture eases the handling of novel concepts, such as understanding of the system by patients at home or the affordability of assistive services. Finally, we provide a proof-of-concept implementation of the architecture and compare the results with other architectures from the literature. PMID:25815449

  18. Adaptive software architecture based on confident HCI for the deployment of sensitive services in Smart Homes.

    PubMed

    Vega-Barbas, Mario; Pau, Iván; Martín-Ruiz, María Luisa; Seoane, Fernando

    2015-03-25

    Smart spaces foster the development of natural and appropriate forms of human-computer interaction by taking advantage of home customization. The interaction potential of the Smart Home, which is a special type of smart space, is of particular interest in fields in which the acceptance of new technologies is limited and restrictive. The integration of smart home design patterns with sensitive solutions can increase user acceptance. In this paper, we present the main challenges that have been identified in the literature for the successful deployment of sensitive services (e.g., telemedicine and assistive services) in smart spaces and a software architecture that models the functionalities of a Smart Home platform that are required to maintain and support such sensitive services. This architecture emphasizes user interaction as a key concept to facilitate the acceptance of sensitive services by end-users and utilizes activity theory to support its innovative design. The application of activity theory to the architecture eases the handling of novel concepts, such as understanding of the system by patients at home or the affordability of assistive services. Finally, we provide a proof-of-concept implementation of the architecture and compare the results with other architectures from the literature.

  19. Advanced Information Processing System (AIPS)-based fault tolerant avionics architecture for launch vehicles

    NASA Technical Reports Server (NTRS)

    Lala, Jaynarayan H.; Harper, Richard E.; Jaskowiak, Kenneth R.; Rosch, Gene; Alger, Linda S.; Schor, Andrei L.

    1990-01-01

    An avionics architecture for the advanced launch system (ALS) that uses validated hardware and software building blocks developed under the advanced information processing system program is presented. The AIPS for ALS architecture defined is preliminary, and reliability requirements can be met by the AIPS hardware and software building blocks that are built using the state-of-the-art technology available in the 1992-93 time frame. The level of detail in the architecture definition reflects the level of detail available in the ALS requirements. As the avionics requirements are refined, the architecture can also be refined and defined in greater detail with the help of analysis and simulation tools. A useful methodology is demonstrated for investigating the impact of the avionics suite to the recurring cost of the ALS. It is shown that allowing the vehicle to launch with selected detected failures can potentially reduce the recurring launch costs. A comparative analysis shows that validated fault-tolerant avionics built out of Class B parts can result in lower life-cycle-cost in comparison to simplex avionics built out of Class S parts or other redundant architectures.

  20. Parallel implementation of high-speed, phase diverse atmospheric turbulence compensation method on a neural network-based architecture

    NASA Astrophysics Data System (ADS)

    Arrasmith, William W.; Sullivan, Sean F.

    2008-04-01

    Phase diversity imaging methods work well in removing atmospheric turbulence and some system effects from predominantly near-field imaging systems. However, phase diversity approaches can be computationally intensive and slow. We present a recently adapted, high-speed phase diversity method using a conventional, software-based neural network paradigm. This phase-diversity method has the advantage of eliminating many time consuming, computationally heavy calculations and directly estimates the optical transfer function from the entrance pupil phases or phase differences. Additionally, this method is more accurate than conventional Zernike-based, phase diversity approaches and lends itself to implementation on parallel software or hardware architectures. We use computer simulation to demonstrate how this high-speed, phase diverse imaging method can be implemented on a parallel, highspeed, neural network-based architecture-specifically the Cellular Neural Network (CNN). The CNN architecture was chosen as a representative, neural network-based processing environment because 1) the CNN can be implemented in 2-D or 3-D processing schemes, 2) it can be implemented in hardware or software, 3) recent 2-D implementations of CNN technology have shown a 3 orders of magnitude superiority in speed, area, or power over equivalent digital representations, and 4) a complete development environment exists. We also provide a short discussion on processing speed.

  1. Developing a Community Based Pre-College Medical Science Collaborative.

    ERIC Educational Resources Information Center

    Shagam, Janet Yagoda

    Designed to assist secondary and post-secondary educators develop community interactive science programs, this manual describes steps undertaken at New Mexico's Albuquerque Technical Vocational Institute to develop pre-college medical science programs that encourage local high school students to consider the college's medical technology program.…

  2. All-optical arithmetic unit with the help of terahertz-optical-asymmetric-demultiplexer-based tree architecture

    NASA Astrophysics Data System (ADS)

    Gayen, Dilip Kumar; Nath Roy, Jitendra

    2008-03-01

    An all-optical arithmetic unit with the help of terahertz-optical-asymmetric-demultiplexer (TOAD)-based tree architecture is proposed. We describe the all-optical arithmetic unit by using a set of all-optical multiplexer, all-optical full-adder, and optical switch. The all-optical arithmetic unit can be used to perform a fast central processor unit using optical hardware components. We have tried to exploit the advantages of both optical tree architecture and TOAD-based switch to design an integrated all-optical circuit that can perform binary addition, addition with carry, subtract with borrow, subtract (2's complement), double, increment, decrement, and transfer operations.

  3. Designing of a risk assessment architecture to analyze potential risks from space weather to space and ground based assets

    NASA Astrophysics Data System (ADS)

    Sattar, Erum

    2016-07-01

    Today's world is more vulnerable to space weather due to ever increased advance and costly space technology deployed in space and on ground. The space weather has a natural potential of posing harmful effects on space and ground based assets and on astronaut's life. This global challenge of space weather essentially demands global and regional preparedness to develop its situational awareness, analyzing risks and devise possible mitigation procedures. Considering risk mitigation architecture as inevitable for all scientific missions, this paper focuses to develop a risk assessment architecture for the space environment and to map its utility in identifying and analyzing potential risks to space and ground based assets from space weather in the South Asia region. Different risk assessment tools will be studied and would conclude in the most effective tool or strategy that may help to develop our capability in identifying, protecting and mitigating from the devastating effects of the space weather.

  4. Feasibility of performing space surveillance tasks with a proposed space-based optical architecture

    NASA Astrophysics Data System (ADS)

    Flohrer, T.; Krag, H.; Klinkrad, H.; Schildknecht, T.

    2011-03-01

    Under ESA contract an industrial consortium including Aboa Space Research Oy (ASRO), the Astronomical Institute of the University of Bern (AIUB), and the Dutch National Aerospace Laboratory (NLR), proposed the observation concept, developed a suitable sensor architecture, and assessed the performance of a space-based optical (SBO) telescope in 2005. The goal of the SBO study was to analyse how the existing knowledge gap in the space debris population in the millimetre and centimetre regime may be closed by means of a passive optical instrument. The SBO instrument was requested to provide statistical information on the space debris population in terms of number of objects and size distribution. The SBO instrument was considered to be a cost-efficient with 20 cm aperture and 6° field-of-view and having flexible integration requirements. It should be possible to integrate the SBO instrument easily as a secondary payload on satellites launched into low-Earth orbits (LEO), or into geostationary orbit (GEO). Thus the selected mission concept only allowed for fix-mounted telescopes, and the pointing direction could be requested freely. Since 2007 ESA focuses space surveillance and tracking activities in the Space Situational Awareness (SSA) preparatory program. Ground-based radars and optical telescopes are studied for the build-up and maintenance of a catalogue of objects. In this paper we analyse how the proposed SBO architecture could contribute to the space surveillance tasks survey and tracking. We assume that the SBO instrumentation is placed into a circular sun-synchronous orbit at 800 km altitude. We discuss the observation conditions of objects at higher altitude, and select an orbit close to the terminator plane. A pointing of the sensor orthogonal to the orbital plane with optimal elevation slightly in positive direction (0° and +5°) is found optimal for accessing the entire GEO regime within one day, implying a very good coverage of controlled objects in

  5. Connecting Requirements to Architecture and Analysis via Model-Based Systems Engineering

    NASA Technical Reports Server (NTRS)

    Cole, Bjorn F.; Jenkins, J. Steven

    2015-01-01

    In traditional systems engineering practice, architecture, concept development, and requirements development are related but still separate activities. Concepts for operation, key technical approaches, and related proofs of concept are developed. These inform the formulation of an architecture at multiple levels, starting with the overall system composition and functionality and progressing into more detail. As this formulation is done, a parallel activity develops a set of English statements that constrain solutions. These requirements are often called "shall statements" since they are formulated to use "shall." The separation of requirements from design is exacerbated by well-meaning tools like the Dynamic Object-Oriented Requirements System (DOORS) that remained separated from engineering design tools. With the Europa Clipper project, efforts are being taken to change the requirements development approach from a separate activity to one intimately embedded in formulation effort. This paper presents a modeling approach and related tooling to generate English requirement statements from constraints embedded in architecture definition.

  6. Coastal Ocean Observing Network - Open Source Architecture for Data Management and Web-Based Data Services

    NASA Astrophysics Data System (ADS)

    Pattabhi Rama Rao, E.; Venkat Shesu, R.; Udaya Bhaskar, T. V. S.

    2012-07-01

    The observations from the oceans are the backbone for any kind of operational services, viz. potential fishing zone advisory services, ocean state forecast, storm surges, cyclones, monsoon variability, tsunami, etc. Though it is important to monitor open Ocean, it is equally important to acquire sufficient data in the coastal ocean through coastal ocean observing systems for re-analysis, analysis and forecast of coastal ocean by assimilating different ocean variables, especially sub-surface information; validation of remote sensing data, ocean and atmosphere model/analysis and to understand the processes related to air-sea interaction and ocean physics. Accurate information and forecast of the state of the coastal ocean at different time scales is vital for the wellbeing of the coastal population as well as for the socio-economic development of the country through shipping, offshore oil and energy etc. Considering the importance of ocean observations in terms of understanding our ocean environment and utilize them for operational oceanography, a large number of platforms were deployed in the Indian Ocean including coastal observatories, to acquire data on ocean variables in and around Indian Seas. The coastal observation network includes HF Radars, wave rider buoys, sea level gauges, etc. The surface meteorological and oceanographic data generated by these observing networks are being translated into ocean information services through analysis and modelling. Centralized data management system is a critical component in providing timely delivery of Ocean information and advisory services. In this paper, we describe about the development of open-source architecture for real-time data reception from the coastal observation network, processing, quality control, database generation and web-based data services that includes on-line data visualization and data downloads by various means.

  7. Mapping the genomic architecture of adaptive traits with interspecific introgressive origin: a coalescent-based approach.

    PubMed

    Hejase, Hussein A; Liu, Kevin J

    2016-01-11

    Recent studies of eukaryotes including human and Neandertal, mice, and butterflies have highlighted the major role that interspecific introgression has played in adaptive trait evolution. A common question arises in each case: what is the genomic architecture of the introgressed traits? One common approach that can be used to address this question is association mapping, which looks for genotypic markers that have significant statistical association with a trait. It is well understood that sample relatedness can be a confounding factor in association mapping studies if not properly accounted for. Introgression and other evolutionary processes (e.g., incomplete lineage sorting) typically introduce variation among local genealogies, which can also differ from global sample structure measured across all genomic loci. In contrast, state-of-the-art association mapping methods assume fixed sample relatedness across the genome, which can lead to spurious inference. We therefore propose a new association mapping method called Coal-Map, which uses coalescent-based models to capture local genealogical variation alongside global sample structure. Using simulated and empirical data reflecting a range of evolutionary scenarios, we compare the performance of Coal-Map against EIGENSTRAT, a leading association mapping method in terms of its popularity, power, and type I error control. Our empirical data makes use of hundreds of mouse genomes for which adaptive interspecific introgression has recently been described. We found that Coal-Map's performance is comparable or better than EIGENSTRAT in terms of statistical power and false positive rate. Coal-Map's performance advantage was greatest on model conditions that most closely resembled empirically observed scenarios of adaptive introgression. These conditions had: (1) causal SNPs contained in one or a few introgressed genomic loci and (2) varying rates of gene flow - from high rates to very low rates where incomplete lineage

  8. Toward an Integrated Executable Architecture and M&S Based Analysis for Counter Terrorism and Homeland Security

    DTIC Science & Technology

    2006-09-01

    SV-5) r ti l ctivity ( - ) t t ti tri ( - ) SV-7 System Performance (MOPs)t rf r ( ) Capability MetricScenario in SE • Reach • Range...construct. Executable Architecture, a Capability Management methodology, provides the means to conduct dynamic analysis of a system, and is emerging as a...vehicle (UAV) focused to locate the radiological source, and by comparing the performance of these assets in terms of various capability based

  9. Achieving Better Buying Power through Acquisition of Open Architecture Software Systems for Web-Based and Mobile Devices

    DTIC Science & Technology

    2015-05-01

    seeking ways to reduce acquisition cost and effort through shared development/use of common OA software system components (proprietary/ open source Apps...Government) open source software  and others Emerging challenges in achieving BBP via OA Web/mobile software systems  Acquisition program managers/staff...Achieving Better Buying Power through Acquisition of Open Architecture Software Systems for Web-Based and Mobile Devices Walt Scacchi and Thomas

  10. Medical smart textiles based on fiber optic technology: an overview.

    PubMed

    Massaroni, Carlo; Saccomandi, Paola; Schena, Emiliano

    2015-04-13

    The growing interest in the development of smart textiles for medical applications is driven by the aim to increase the mobility of patients who need a continuous monitoring of such physiological parameters. At the same time, the use of fiber optic sensors (FOSs) is gaining large acceptance as an alternative to traditional electrical and mechanical sensors for the monitoring of thermal and mechanical parameters. The potential impact of FOSs is related to their good metrological properties, their small size and their flexibility, as well as to their immunity from electromagnetic field. Their main advantage is the possibility to use textile based on fiber optic in a magnetic resonance imaging environment, where standard electronic sensors cannot be employed. This last feature makes FOSs suitable for monitoring biological parameters (e.g., respiratory and heartbeat monitoring) during magnetic resonance procedures. Research interest in combining FOSs and textiles into a single structure to develop wearable sensors is rapidly growing. In this review we provide an overview of the state-of-the-art of textiles, which use FOSs for monitoring of mechanical parameters of physiological interest. In particular we briefly describe the working principle of FOSs employed in this field and their relevant advantages and disadvantages. Also reviewed are their applications for the monitoring of mechanical parameters of physiological interest.

  11. Iris-based medical analysis by geometric deformation features.

    PubMed

    Ma, Lin; Zhang, D; Li, Naimin; Cai, Yan; Zuo, Wangmeng; Wang, Kuanguan

    2013-01-01

    Iris analysis studies the relationship between human health and changes in the anatomy of the iris. Apart from the fact that iris recognition focuses on modeling the overall structure of the iris, iris diagnosis emphasizes the detecting and analyzing of local variations in the characteristics of irises. This paper focuses on studying the geometrical structure changes in irises that are caused by gastrointestinal diseases, and on measuring the observable deformations in the geometrical structures of irises that are related to roundness, diameter and other geometric forms of the pupil and the collarette. Pupil and collarette based features are defined and extracted. A series of experiments are implemented on our experimental pathological iris database, including manual clustering of both normal and pathological iris images, manual classification by non-specialists, manual classification by individuals with a medical background, classification ability verification for the proposed features, and disease recognition by applying the proposed features. The results prove the effectiveness and clinical diagnostic significance of the proposed features and a reliable recognition performance for automatic disease diagnosis. Our research results offer a novel systematic perspective for iridology studies and promote the progress of both theoretical and practical work in iris diagnosis.

  12. Medical Smart Textiles Based on Fiber Optic Technology: An Overview

    PubMed Central

    Massaroni, Carlo; Saccomandi, Paola; Schena, Emiliano

    2015-01-01

    The growing interest in the development of smart textiles for medical applications is driven by the aim to increase the mobility of patients who need a continuous monitoring of such physiological parameters. At the same time, the use of fiber optic sensors (FOSs) is gaining large acceptance as an alternative to traditional electrical and mechanical sensors for the monitoring of thermal and mechanical parameters. The potential impact of FOSs is related to their good metrological properties, their small size and their flexibility, as well as to their immunity from electromagnetic field. Their main advantage is the possibility to use textile based on fiber optic in a magnetic resonance imaging environment, where standard electronic sensors cannot be employed. This last feature makes FOSs suitable for monitoring biological parameters (e.g., respiratory and heartbeat monitoring) during magnetic resonance procedures. Research interest in combining FOSs and textiles into a single structure to develop wearable sensors is rapidly growing. In this review we provide an overview of the state-of-the-art of textiles, which use FOSs for monitoring of mechanical parameters of physiological interest. In particular we briefly describe the working principle of FOSs employed in this field and their relevant advantages and disadvantages. Also reviewed are their applications for the monitoring of mechanical parameters of physiological interest. PMID:25871010

  13. Radiation-Based Medical Imaging Techniques: An Overview

    NASA Astrophysics Data System (ADS)

    Prior, John O.; Lecoq, Paul

    This chapter will present an overview of two radiation-based medical imaging techniques using radiopharmaceuticals used in nuclear medicine/molecular imaging, namely, single-photon emission computed tomography (SPECT) and positron emission tomography (PET). The relative merits in terms of radiation sensitivity and image resolution of SPECT and PET will be compared to the main conventional radiologic modalities that are computed tomography (CT) and magnetic resonance (MR) imaging. Differences in terms of temporal resolution will also be outlined, as well as the other similarities and dissimilarities of these two techniques, including their latest and upcoming multimodality combination. The main clinical applications are briefly described and examples of specific SPECT and PET radiopharmaceuticals are listed. SPECT and PET imaging will be then further detailed in the two subsequent chapters describing in greater depth the basics and future trends of each technique (see Chaps. 37, "SPECT Imaging: Basics and New Trends" 10.1007/978-3-642-13271-1_37 and 38, "PET Imaging: Basics and New Trends" 10.1007/978-3-642-13271-1_38.

  14. Architectural design for a low cost FPGA-based traffic signal detection system in vehicles

    NASA Astrophysics Data System (ADS)

    López, Ignacio; Salvador, Rubén; Alarcón, Jaime; Moreno, Félix

    2007-05-01

    In this paper we propose an architecture for an embedded traffic signal detection system. Development of Advanced Driver Assistance Systems (ADAS) is one of the major trends of research in automotion nowadays. Examples of past and ongoing projects in the field are CHAMELEON ("Pre-Crash Application all around the vehicle" IST 1999-10108), PREVENT (Preventive and Active Safety Applications, FP6-507075, http://www.prevent-ip.org/) and AVRT in the US (Advanced Vision-Radar Threat Detection (AVRT): A Pre-Crash Detection and Active Safety System). It can be observed a major interest in systems for real-time analysis of complex driving scenarios, evaluating risk and anticipating collisions. The system will use a low cost CCD camera on the dashboard facing the road. The images will be processed by an Altera Cyclone family FPGA. The board does median and Sobel filtering of the incoming frames at PAL rate, and analyzes them for several categories of signals. The result is conveyed to the driver. The scarce resources provided by the hardware require an architecture developed for optimal use. The system will use a combination of neural networks and an adapted blackboard architecture. Several neural networks will be used in sequence for image analysis, by reconfiguring a single, generic hardware neural network in the FPGA. This generic network is optimized for speed, in order to admit several executions within the frame rate. The sequence will follow the execution cycle of the blackboard architecture. The global, blackboard architecture being developed and the hardware architecture for the generic, reconfigurable FPGA perceptron will be explained in this paper. The project is still at an early stage. However, some hardware implementation results are already available and will be offered in the paper.

  15. A Novel Approach to Noise-Filtering Based on a Gain-Scheduling Neural Network Architecture

    NASA Technical Reports Server (NTRS)

    Troudet, T.; Merrill, W.

    1994-01-01

    A gain-scheduling neural network architecture is proposed to enhance the noise-filtering efficiency of feedforward neural networks, in terms of both nominal performance and robustness. The synergistic benefits of the proposed architecture are demonstrated and discussed in the context of the noise-filtering of signals that are typically encountered in aerospace control systems. The synthesis of such a gain-scheduled neurofiltering provides the robustness of linear filtering, while preserving the nominal performance advantage of conventional nonlinear neurofiltering. Quantitative performance and robustness evaluations are provided for the signal processing of pitch rate responses to typical pilot command inputs for a modern fighter aircraft model.

  16. Flexible architecture of data acquisition firmware based on multi-behaviors finite state machine

    NASA Astrophysics Data System (ADS)

    Arpaia, Pasquale; Cimmino, Pasquale

    2016-11-01

    A flexible firmware architecture for different kinds of data acquisition systems, ranging from high-precision bench instruments to low-cost wireless transducers networks, is presented. The key component is a multi-behaviors finite state machine, easily configurable to both low- and high-performance requirements, to diverse operating systems, as well as to on-line and batch measurement algorithms. The proposed solution was validated experimentally on three case studies with data acquisition architectures: (i) concentrated, in a high-precision instrument for magnetic measurements at CERN, (ii) decentralized, for telemedicine remote monitoring of patients at home, and (iii) distributed, for remote monitoring of building's energy loss.

  17. A Standards-Based Architecture Proposal for Integrating Patient mHealth Apps to Electronic Health Record Systems

    PubMed Central

    Fontelo, P.; Rossi, E.; Ackerman, MJ

    2015-01-01

    Summary Background Mobile health Applications (mHealth Apps) are opening the way to patients’ responsible and active involvement with their own healthcare management. However, apart from Apps allowing patient’s access to their electronic health records (EHRs), mHealth Apps are currently developed as dedicated “island systems”. Objective Although much work has been done on patient’s access to EHRs, transfer of information from mHealth Apps to EHR systems is still low. This study proposes a standards-based architecture that can be adopted by mHealth Apps to exchange information with EHRs to support better quality of care. Methods Following the definition of requirements for the EHR/mHealth App information exchange recently proposed, and after reviewing current standards, we designed the architecture for EHR/mHealth App integration. Then, as a case study, we modeled a system based on the proposed architecture aimed to support home monitoring for congestive heart failure patients. We simulated such process using, on the EHR side, OpenMRS, an open source longitudinal EHR and, on the mHealth App side, the iOS platform. Results The integration architecture was based on the bi-directional exchange of standard documents (clinical document architecture rel2 – CDA2). In the process, the clinician “prescribes” the home monitoring procedures by creating a CDA2 prescription in the EHR that is sent, encrypted and de-identified, to the mHealth App to create the monitoring calendar. At the scheduled time, the App alerts the patient to start the monitoring. After the measurements are done, the App generates a structured CDA2-compliant monitoring report and sends it to the EHR, thus avoiding local storage. Conclusions The proposed architecture, even if validated only in a simulation environment, represents a step forward in the integration of personal mHealth Apps into the larger health-IT ecosystem, allowing the bi-directional data exchange between patients and

  18. ARC-VM: An architecture real options complexity-based valuation methodology for military systems-of-systems acquisitions

    NASA Astrophysics Data System (ADS)

    Domercant, Jean Charles

    The combination of today's national security environment and mandated acquisition policies makes it necessary for military systems to interoperate with each other to greater degrees. This growing interdependency results in complex Systems-of-Systems (SoS) that only continue to grow in complexity to meet evolving capability needs. Thus, timely and affordable acquisition becomes more difficult, especially in the face of mounting budgetary pressures. To counter this, architecting principles must be applied to SoS design. The research objective is to develop an Architecture Real Options Complexity-Based Valuation Methodology (ARC-VM) suitable for acquisition-level decision making, where there is a stated desire for more informed tradeoffs between cost, schedule, and performance during the early phases of design. First, a framework is introduced to measure architecture complexity as it directly relates to military SoS. Development of the framework draws upon a diverse set of disciplines, including Complexity Science, software architecting, measurement theory, and utility theory. Next, a Real Options based valuation strategy is developed using techniques established for financial stock options that have recently been adapted for use in business and engineering decisions. The derived complexity measure provides architects with an objective measure of complexity that focuses on relevant complex system attributes. These attributes are related to the organization and distribution of SoS functionality and the sharing and processing of resources. The use of Real Options provides the necessary conceptual and visual framework to quantifiably and traceably combine measured architecture complexity, time-valued performance levels, as well as programmatic risks and uncertainties. An example suppression of enemy air defenses (SEAD) capability demonstrates the development and usefulness of the resulting architecture complexity & Real Options based valuation methodology. Different

  19. A Competency-Based Clinical Chemistry Course for the Associate Degree Medical Laboratory Technician Graduate in a Medical Technology Baccalaureate Program.

    ERIC Educational Resources Information Center

    Buccelli, Pamela

    Presented is a project that developed a competency-based clinical chemistry course for associate degree medical laboratory technicians (MLT) in a medical technology (MT) baccalaureate program. Content of the course was based upon competencies expected of medical technologists at career-entry as defined in the statements adopted in 1976 by the…

  20. Wavelet Packets-Based Blind Watermarking for Medical Image Management

    PubMed Central

    Mostafa, Salwa A.K.; El-sheimy, Naser; Tolba, A.S.; Abdelkader, F.M.; Elhindy, Hisham M.

    2010-01-01

    The last decade has witnessed an explosive use of medical images and Electronics Patient Record (EPR) in the healthcare sector for facilitating the sharing of patient information and exchange between networked hospitals and healthcare centers. To guarantee the security, authenticity and management of medical images and information through storage and distribution, the watermarking techniques are growing to protect the medical healthcare information. This paper presents a technique for embedding the EPR information in the medical image to save storage space and transmission overheads and to guarantee security of the shared data. In this paper a new method for protecting the patient information in which the information is embedded as a watermark in the discrete wavelet packet transform (DWPT) of the medical image using the hospital logo as a reference image. The patient information is coded by an error correcting code (ECC), BCH code, to enhance the robustness of the proposed method. The scheme is blind so that the EPR can be extracted from the medical image without the need of the original image. Therefore, this proposed technique is useful in telemedicine applications. Performance of the proposed method was tested using four modalities of medical images; MRA, MRI, Radiological, and CT. Experimental results showed no visible difference between the watermarked and the original image. Moreover, the proposed watermarking method is robust against a wide range of attacks such as JPEG coding, Gaussian noise addition, histogram equalization, gamma correction, contrast adjustment, and sharpen filter and rotation. PMID:20700520