Early allograft dysfunction in liver transplantation with donation after cardiac death donors results in inferior survival.

PubMed

Lee, David D; Singh, Amandeep; Burns, Justin M; Perry, Dana K; Nguyen, Justin H; Taner, C Burcin

2014-12-01

Donation after cardiac death (DCD) liver allografts have been associated with increased morbidity from primary nonfunction, biliary complications, early allograft failure, cost, and mortality. Early allograft dysfunction (EAD) after liver transplantation has been found to be associated with inferior patient and graft survival. In a cohort of 205 consecutive liver-only transplant patients with allografts from DCD donors at a single center, the incidence of EAD was found to be 39.5%. The patient survival rates for those with no EAD and those with EAD at 1, 3, and 5 years were 97% and 89%, 79% and 79%, and 61% and 54%, respectively (P = 0.009). Allograft survival rates for recipients with no EAD and those with EAD at 1, 3, and 5 years were 90% and 75%, 72% and 64%, and 53% and 43%, respectively (P = 0.003). A multivariate analysis demonstrated a significant association between the development of EAD and the cold ischemia time [odds ratio (OR) = 1.26, 95% confidence interval (CI) = 1.01-1.56, P = 0.037] and hepatocellular cancer as a secondary diagnosis in recipients (OR = 2.26, 95% CI = 1.11-4.58, P = 0.025). There was no correlation between EAD and the development of ischemic cholangiopathy. In conclusion, EAD results in inferior patient and graft survival in recipients of DCD liver allografts. Understanding the events that cause EAD and developing preventive or early therapeutic approaches should be the focus of future investigations. © 2014 American Association for the Study of Liver Diseases.

Female-biased attraction of Oriental fruit fly, bactrocera dorsalis (Hendel), to a blend of host fruit volatiles from Terminalia catappa L.

PubMed

Siderhurst, Matthew S; Jang, Eric B

2006-11-01

Coupled gas chromatography-electroantennogram detection (GC-EAD) analysis of volatiles from tropical almond fruit, Terminalia catappa L., revealed 22 compounds that were detected by antennae of oriental fruit fly females, Bactrocera dorsalis (Hendel). Both solid-phase microextraction (SPME) and Porapak Q were used for sampling odors in fruit headspace, with SPME collections producing larger EAD responses from a greater number of compounds. Geranyl acetate and methyl eugenol elicited the largest EAD responses. A synthetic blend containing SPME collected, EAD stimulatory compounds showed female-biased attraction in laboratory wind tunnel bioassays, but heavily male-biased trap captures in a larger olfactometer arena. A nine-component subset of compounds eliciting relatively small EAD responses (EAD minor) and consisting of equal parts ethanol, ethyl acetate, ethyl hexanoate, hexyl acetate, linalyl acetate, ethyl nonanate, nonyl acetate, ethyl cinnamate, and (E)-beta-farnesene, attracted mainly females. This EAD minor blend was as attractive to females and much less attractive to males when compared to torula yeast in field cage experiments using glass McPhail traps. Similar results were obtained with outdoor rotating olfactometer tests in which the EAD minor blend was almost completely inactive for males.

Ajuga decumbens stimulates mesenchymal stem cell differentiation and regenerates cartilage in a rabbit osteoarthritis model

PubMed Central

Sawada, Yoko; Sugimoto, Atsushi; Osaki, Tomohiro; Okamoto, Yoshiharu

2018-01-01

In a previous study by our group, Ajuga decumbens extract (ADE) was demonstrated to decrease the number of osteoclasts in subchondral bone and to have a synergistic effect with glucosamine in improving cartilaginous injuries in a rabbit model of osteoarthritis. In the present study, a concentrate of the useful fraction of ADE, termed extra ADE (EADE), which includes higher concentrations of the active component 20-hydroxyecdysone, was evaluated for its efficacy to accelerate the healing of experimental cartilage injury. Cartilage injuries were surgically induced in rabbits by creating three holes; one in the articular cartilage of the medial trochlea and two in the trochlear sulcus of the distal femur. The rabbits were divided into the following four groups (n=3 in each): Control, ADE (0.5 g/kg), low dosage EADE (0.05 g/kg; low EADE) and high dosage EADE (0.5 g/kg; high EADE). ADE and EADE were dissolved in tap water and each dosage was orally administered every day for 3 weeks. At the end of the experimental period, histological analysis indicated that the cartilage matrix was regenerated in the low and high EADE groups. On counting of cells in the histological specimens, it was determined that the mean number of osteoclasts per 100 osteoblasts in subchondral bone was lower in the high EADE group compared with the control group. Furthermore, the results indicated that treatment with EADE (1–100 µg/ml) stimulated chondrogenic differentiation of mesenchymal stem cells and induced proteoglycan production to a greater extent than the control in vitro. EADE treatment (10 and 100 µg/ml) was also observed to significantly attenuate interleukin-1β-induced prostaglandin E2 production in chondrocytes (P<0.05). In summary, the results of the present study suggest that EADE may have greater curative effects on bone injury compared with the currently used therapeutic ADE. PMID:29725360

Improved electroacoustic dewatering (EAD) belt press for food products. Phase 3, Technical progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-02-01

Battelle`s electroacoustic dewatering (EAD) process improves the performance of mechanical dewatering processes for several food products (such as corn fiber) by superimposing electric and ultrasonic fields. EAD has the potential to save 0.027 to 0.035 quad/yr energy by 1995 in the food processing industry, which consumed 0.15 to 0.18 quad in 1986. This report covers Phase III for demonstrating the EAD prototype on corn wet milling products (corn fiber and gluten); only Task 1 (prototype preparation and planning) was completed. EAD performance was examined in the laboratory; availability of a test site was examined. The single-roll, postdewatering EAD belt pressmore » prototype can accept material predewatered by a screw press, centrifuge, or any other mechanical dewatering device. The two-belt system, utilizing a copper-polymer cathode belt, performed as well as the three-belt system used in Phase II.« less

Biosecurity and the management of emergency animal disease among commercial beef producers in New South Wales and Queensland (Australia).

PubMed

Hernández-Jover, M; Higgins, V; Bryant, M; Rast, L; McShane, C

2016-11-01

Australia places great importance on the prevention and management of emergency animal diseases (EAD), with strict quarantine measures offshore and at the border. Livestock producers are crucial for disease control onshore; however, limited information is available on commercial livestock producers' practices in relation to the management of disease risks. The aims of this paper are to investigate how commercial beef producers in Australia's Northern and Southern beef zones manage EADs and to identify drivers for effective biosecurity and EAD prevention. This paper forms part of a broader mixed methods research project involving an analysis of literature and current policies, qualitative semi-structured interviews with government and industry stakeholders and a cross-sectional study among beef producers. The cross-sectional study used a postal survey (n=182) and face-to-face interviews (n=34) to gather data on beef producers' knowledge and practices on biosecurity and EADs and their communication networks. Findings indicate that producers are uncertain about the roles and responsibilities of stakeholders involved in biosecurity and EAD management. This uncertainty may create confusion about EAD management and impact upon producers' willingness to report animal disease, with over 20% reporting the last veterinary contact more than five years ago and an additional 8.5% who had never contacted a veterinarian. Producers had a generally high awareness of the key sources of animal disease risk and they prioritise herd health planning as part of their everyday practices. Over 40% of producers had limited knowledge of the meaning of EAD; and EAD and biosecurity planning was given a low priority, primarily due to the perceived limited likelihood of an EAD event in Australia and the belief that EAD prevention is primarily the role of government. Only a moderate implementation of biosecurity practices, such as isolating incoming animals, having a single property entry point or keeping visitors' records was reported. If faced with an unusual disease event, most producers would contact their private or government veterinarian; however, in some instances most would also treat themselves and over a third would do nothing. Findings from this study suggest that there is a need for better coordination between stakeholders to encourage a shared biosecurity and EAD understanding and to communicate a consistent message to all stakeholders including producers. Further, there is a need for improving producer awareness of the importance of EAD prevention and biosecurity practices as well as the stakeholders' roles within the broader animal health system. Copyright © 2016 Elsevier B.V. All rights reserved.

A Structure Standard for Archival Context: EAC-CPF Is Here

ERIC Educational Resources Information Center

Dryden, Jean

2010-01-01

The archival community's new descriptive standard, "Encoded Archival Context" for Corporate Bodies, Persons, and Families (EAC-CPF), supports the sharing of descriptions of records creators and is a significant addition to the suite of standards for archival description. EAC-CPF is a data structure standard similar to its older sibling EAD…

Quantum-Chemical Study of the Adsorption of DMMP and Sarin on gamma-Al2O3

DTIC Science & Technology

2007-02-01

In this and in the following section, ∆Eads is not corrected for zero-point vibrational energy ( ZPE ); however, a counterpoise correction for basis set...Ångstroms and the bond angle is in degrees. Values in parentheses are BSSE-corrected (∆Eads C ) results. ∆Eads has not been corrected for ZPE . b 6-31G...sets. The ∆ Eads C values are given in parentheses. No ZPE corrections have been applied. e The basis sets used were 6-311G(df) for Sarin and for the Al

ModelArchiver—A program for facilitating the creation of groundwater model archives

USGS Publications Warehouse

Winston, Richard B.

2018-03-01

ModelArchiver is a program designed to facilitate the creation of groundwater model archives that meet the requirements of the U.S. Geological Survey (USGS) policy (Office of Groundwater Technical Memorandum 2016.02, https://water.usgs.gov/admin/memo/GW/gw2016.02.pdf, https://water.usgs.gov/ogw/policy/gw-model/). ModelArchiver version 1.0 leads the user step-by-step through the process of creating a USGS groundwater model archive. The user specifies the contents of each of the subdirectories within the archive and provides descriptions of the archive contents. Descriptions of some files can be specified automatically using file extensions. Descriptions also can be specified individually. Those descriptions are added to a readme.txt file provided by the user. ModelArchiver moves the content of the archive to the archive folder and compresses some folders into .zip files.As part of the archive, the modeler must create a metadata file describing the archive. The program has a built-in metadata editor and provides links to websites that can aid in creation of the metadata. The built-in metadata editor is also available as a stand-alone program named FgdcMetaEditor version 1.0, which also is described in this report. ModelArchiver updates the metadata file provided by the user with descriptions of the files in the archive. An optional archive list file generated automatically by ModelMuse can streamline the creation of archives by identifying input files, output files, model programs, and ancillary files for inclusion in the archive.

Paradoxical Effects of Sodium-Calcium Exchanger Inhibition on Torsade de Pointes and Early Afterdepolarization in a Heart Failure Rabbit Model.

PubMed

Chang, Po-Cheng; Lu, Yu-Ying; Lee, Hui-Ling; Lin, Shien-Fong; Chu, Yen; Wen, Ming-Shien; Chou, Chung-Chuan

2018-05-03

Calcium homeostasis plays an important role in development of early afterdepolarizations (EADs) and torsade de pointes (TdP). The role of sodium-calcium exchanger (NCX) inhibition in genesis secondary Ca rise and EADs-TdP is still debated. Dual voltage and intracellular Ca optical mapping were conducted in 6 control and 9 failing rabbit hearts. After baseline electrophysiological and optical mapping studies, E4031 was given to simulate long QT syndrome. ORM-10103 was then administrated to examine the electrophysiological effects on EAD-TdP development. E4031 enhanced secondary Ca rise, EADs development and TdP inducibility in both control and failing hearts. The results showed that ORM-10103 reduced premature ventricular beats (PVBs) but was unable to suppress the inducibility of TdP or EADs. The electrophysiological effects of ORM-10103 included prolongation of action potential duration (APD) and increased APD heterogeneity in failing hearts. ORM10103 had a neutral effect on the amplitude of secondary Cai rise in control and HF groups. In this model, most EADs generated from the long-short APD junction area. In conclusion, highly selective NCX inhibition with ORM-10103 reduced PVB burden but was unable to suppress secondary Ca rise, EADs development nor inducibility of TdP. The possible electrophysiological mechanisms include APD prolongation and increased APD heterogeneity.

78 FR 76050 - Airworthiness Directives; EADS CASA (Type Certificate Previously Held by Construcciones...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-16

... Airworthiness Directives; EADS CASA (Type Certificate Previously Held by Construcciones Aeron[aacute]uticas, S.A... Certificate Previously Held by Construcciones Aeron[aacute]uticas, S.A.) Model C-212-CB, C-212-CC, C-212-CD, C... changed paragraph (c) of this AD to remove EADS CASA (Type Certificate previously held by Construcciones...

Property Investigation of Laser Cladded, Laser Melted and Electron Beam Melted Ti-Al6-V4

DTIC Science & Technology

2006-05-01

UNCLASSIFIED/UNLIMITED UNCLASSIFIED/UNLIMITED Figure 3: Examples of electron beam melted net shape parts; powder bed [3]. 1.4 Laser Cladding ...description, www.arcam.com. [4] K.-H. Hermann, S. Orban, S. Nowotny, Laser Cladding of Titanium Alloy Ti6242 to Restore Damaged Blades, Proceedings...Property Investigation of Laser Cladded , Laser Melted and Electron Beam Melted Ti-Al6-V4 Johannes Vlcek EADS Deutschland GmbH Corporate Research

Donor information based prediction of early allograft dysfunction and outcome in liver transplantation.

PubMed

Hoyer, Dieter P; Paul, Andreas; Gallinat, Anja; Molmenti, Ernesto P; Reinhardt, Renate; Minor, Thomas; Saner, Fuat H; Canbay, Ali; Treckmann, Jürgen W; Sotiropoulos, Georgios C; Mathé, Zoltan

2015-01-01

Poor initial graft function was recently newly defined as early allograft dysfunction (EAD) [Olthoff KM, Kulik L, Samstein B, et al. Validation of a current definition of early allograft dysfunction in liver transplant recipients and analysis of risk factors. Liver Transpl 2010; 16: 943]. Aim of this analysis was to evaluate predictive donor information for development of EAD. Six hundred and seventy-eight consecutive adult patients (mean age 51.6 years; 60.3% men) who received a primary liver transplantation (LT) (09/2003-12/2011) were included. Standard donor data were correlated with EAD and outcome by univariable/multivariable logistic regression and Cox proportional hazards to identify prognostic donor factors after adjustment for recipient confounders. Estimates of relevant factors were utilized for construction of a new continuous risk index to develop EAD. 38.7% patients developed EAD. 30-day survival of grafts with and without EAD was 59.8% and 89.7% (P < 0.0001). 30-day survival of patients with and without EAD was 68.5% and 93.1% (P < 0.0001) respectively. Donor body mass index (P = 0.0112), gGT (P = 0.0471), macrosteatosis (P = 0.0006) and cold ischaemia time (CIT) (P = 0.0031) were predictors of EAD. Internal cross validation showed a high predictive value (c-index = 0.622). Early allograft dysfunction correlates with early results of LT and can be predicted by donor data only. The newly introduced risk index potentially optimizes individual decisions to accept/decline high risk organs. Outcome of these organs might be improved by shortening CIT. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Optimization of the propulsion for multistage solid rocket motor launchers

NASA Astrophysics Data System (ADS)

Calabro, M.; Dufour, A.; Macaire, A.

2002-02-01

Some tools focused on a rapid multidisciplinary optimization capability for multistage launch vehicle design were developed at EADS-LV. These tools may be broken down into two categories, those related to propulsion design optimization and a computer code devoted to trajectories and under constraints optimization. Both are linked in order to obtain optimal vehicle design after an iterative process. After a description of the two categories tools, an example of application is given on a small space launcher.

Propulsion Systems

DTIC Science & Technology

2011-03-31

Manual 91 - 710 Vol. 2 ( AFSPCMAN 91 - 710 V2). 8. Astrium EADS. 2010. cs.astrium.eads.net. April. 9. Astrium EADS. 2010. : http...of the High Energy Density Matter (HEDM) Conference. Albuquerque, NM, February 24-27, (Phillips Lab PL-CP- 91 -3003, p. 3 ). 104. Sullivan, D. J...Chapter 3 . DATES COVERED (From - To) 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Chapter 18 - Propulsion Systems 5b. GRANT NUMBER 5c. PROGRAM ELEMENT

An automated approach to detecting signals in electroantennogram data

USGS Publications Warehouse

Slone, D.H.; Sullivan, B.T.

2007-01-01

Coupled gas chromatography/electroantennographic detection (GC-EAD) is a widely used method for identifying insect olfactory stimulants present in mixtures of volatiles, and it can greatly accelerate the identification of insect semiochemicals. In GC-EAD, voltage changes across an insect's antenna are measured while the antenna is exposed to compounds eluting from a gas chromatograph. The antenna thus serves as a selective GC detector whose output can be compared to that of a "general" GC detector, commonly a flame ionization detector. Appropriate interpretation of GC-EAD results requires that olfaction-related voltage changes in the antenna be distinguishable from background noise that arises inevitably from antennal preparations and the GC-EAD-associated hardware. In this paper, we describe and compare mathematical algorithms for discriminating olfaction-generated signals in an EAD trace from background noise. The algorithms amplify signals by recognizing their characteristic shape and wavelength while suppressing unstructured noise. We have found these algorithms to be both powerful and highly discriminatory even when applied to noisy traces where the signals would be difficult to discriminate by eye. This new methodology removes operator bias as a factor in signal identification, can improve realized sensitivity of the EAD system, and reduces the number of runs required to confirm the identity of an olfactory stimulant. ?? 2007 Springer Science+Business Media, LLC.

Psychometric characteristics of the Eating and Appraisal Due to Emotions and Stress Questionnaire and obesity in Mexican university students.

PubMed

Lazarevich, Irina; Irigoyen-Camacho, María Esther; Velazquez-Alva, María del Consuelo; Salinas-Ávila, Jaqueline

2015-06-01

Emotional eating has been defined as eating in a response to negative emotions and it is associated with weight gain. The English version of Eating Appraisal Due to Emotions and Stress Questionnaire (EADES) was developed to assess how individuals use food in order to cope with stress and emotions. To analyze psychometric characteristics of Spanish version of EADES and to identify whether the constructs of EADES were associated with obesity in university students. The EADES (Spanish version) was administered to 232 Mexican university students from 18 to 29 years old. Body Mass Index (BMI) was calculated. A test-retest evaluation was conducted with 75 participants. Cronbach's alpha of EADES was 0.92; the interclass correlation coefficient was 0.88. Regarding BMI and EADES results, the subscale Emotion and Stress Related Eating was significantly associated with obesity (p = 0.026). Through factor analysis of the instrument, three factors were extracted and items that showed factor loading < 0.40 were eliminated. 40 items remained in the questionnaire. With regard to obesity and the 40-items version of the instrument, a statistically significance association was found for the total score (OR = 0.973, p = 0.020) and for the factor Self-confidence related to Emotional Eating component (OR = 0.940, p = 0.026). A good internal consistency and temporal stability of the Spanish version of the instrument were found; the 40-item EADES version was positively associated with obesity. This instrument could be useful in assessing emotional eating. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

A sharp, robust, and quantitative method by liquid chromatography tandem mass spectrometry for the measurement of EAD for acute radiation syndrome and its application.

PubMed

Zhang, Yiwei; Li, Jian; Meng, Zhiyun; Zhu, Xiaoxia; Gan, Hui; Gu, Ruolan; Wu, Zhuona; Zheng, Ying; Wei, Jinbin; Dou, Guifang

2017-06-15

17-Ethinyl-3,17-dihydroxyandrost-5-ene (EAD) is an agent designed for the treatment of acute radiation syndrome (ARS). Given its vital role played in the prevention and mitigation of ARS, the development of a sharp, sensitive and robust liquid chromatography tandem mass spectrometry (LC-MS/MS) method to monitor the metabolism of EAD in vivo was crucial. A new method was constructed and validated for the determination of EAD with the internal standard of androst-5-ene-3β,17β-diol (5-AED). The blood samples were precipitated with methanol, centrifuged, from which the supernatant was separated on UPLC with C18 column and eluted in gradient with acetonitrile and Milli-Q water both containing 0.1% formic acid (FA). Quantification was performed by a triple quadrupole mass spectrometer with electro spray ionization (ESI) in multiple reactive monitoring (MRM) positive mode. A good linearity was obtained with R>0.99 for EAD within its calibration range from 5 to 1000ngmL -1 with a lowest limit of quantification (LLOQ) of 5ngmL -1 . Inter- and intra-day accuracy and precision of three levels of quality control (QC) samples were within the range of 15%, while the LLOQ was within 20%. Samples were stable under the circumstances of the experiments. The method was simple, accurate and robust applied to determine the concentrations of EAD in Wistar rat after a single administration of EAD orally at the dose of 100mgkg -1 . Copyright © 2017 Elsevier B.V. All rights reserved.

A Study of Early Afterdepolarizations in a Model for Human Ventricular Tissue

PubMed Central

Vandersickel, Nele; Kazbanov, Ivan V.; Nuitermans, Anita; Weise, Louis D.; Pandit, Rahul; Panfilov, Alexander V.

2014-01-01

Sudden cardiac death is often caused by cardiac arrhythmias. Recently, special attention has been given to a certain arrhythmogenic condition, the long-QT syndrome, which occurs as a result of genetic mutations or drug toxicity. The underlying mechanisms of arrhythmias, caused by the long-QT syndrome, are not fully understood. However, arrhythmias are often connected to special excitations of cardiac cells, called early afterdepolarizations (EADs), which are depolarizations during the repolarizing phase of the action potential. So far, EADs have been studied mainly in isolated cardiac cells. However, the question on how EADs at the single-cell level can result in fibrillation at the tissue level, especially in human cell models, has not been widely studied yet. In this paper, we study wave patterns that result from single-cell EAD dynamics in a mathematical model for human ventricular cardiac tissue. We induce EADs by modeling experimental conditions which have been shown to evoke EADs at a single-cell level: by an increase of L-type Ca currents and a decrease of the delayed rectifier potassium currents. We show that, at the tissue level and depending on these parameters, three types of abnormal wave patterns emerge. We classify them into two types of spiral fibrillation and one type of oscillatory dynamics. Moreover, we find that the emergent wave patterns can be driven by calcium or sodium currents and we find phase waves in the oscillatory excitation regime. From our simulations we predict that arrhythmias caused by EADs can occur during normal wave propagation and do not require tissue heterogeneities. Experimental verification of our results is possible for experiments at the cell-culture level, where EADs can be induced by an increase of the L-type calcium conductance and by the application of I blockers, and the properties of the emergent patterns can be studied by optical mapping of the voltage and calcium. PMID:24427289

Performance evaluation of the Engineering Analysis and Data Systems (EADS) 2

NASA Technical Reports Server (NTRS)

Debrunner, Linda S.

1994-01-01

The Engineering Analysis and Data System (EADS)II (1) was installed in March 1993 to provide high performance computing for science and engineering at Marshall Space Flight Center (MSFC). EADS II increased the computing capabilities over the existing EADS facility in the areas of throughput and mass storage. EADS II includes a Vector Processor Compute System (VPCS), a Virtual Memory Compute System (CFS), a Common Output System (COS), as well as Image Processing Station, Mini Super Computers, and Intelligent Workstations. These facilities are interconnected by a sophisticated network system. This work considers only the performance of the VPCS and the CFS. The VPCS is a Cray YMP. The CFS is implemented on an RS 6000 using the UniTree Mass Storage System. To better meet the science and engineering computing requirements, EADS II must be monitored, its performance analyzed, and appropriate modifications for performance improvement made. Implementing this approach requires tool(s) to assist in performance monitoring and analysis. In Spring 1994, PerfStat 2.0 was purchased to meet these needs for the VPCS and the CFS. PerfStat(2) is a set of tools that can be used to analyze both historical and real-time performance data. Its flexible design allows significant user customization. The user identifies what data is collected, how it is classified, and how it is displayed for evaluation. Both graphical and tabular displays are supported. The capability of the PerfStat tool was evaluated, appropriate modifications to EADS II to optimize throughput and enhance productivity were suggested and implemented, and the effects of these modifications on the systems performance were observed. In this paper, the PerfStat tool is described, then its use with EADS II is outlined briefly. Next, the evaluation of the VPCS, as well as the modifications made to the system are described. Finally, conclusions are drawn and recommendations for future worked are outlined.

Carvedilol analogue inhibits triggered activities evoked by both early and delayed afterdepolarizations.

PubMed

Maruyama, Mitsunori; Xiao, Jianmin; Zhou, Qiang; Vembaiyan, Kannan; Chua, Su-Kiat; Rubart-von der Lohe, Michael; Lin, Shien-Fong; Back, Thomas G; Chen, S R Wayne; Chen, Peng-Sheng

2013-01-01

Carvedilol and its analogues suppress delayed afterdepolarizations (DADs) and catecholaminergic polymorphic ventricular tachycardias by direct action on the cardiac ryanodine receptor type 2 (RyR2). To test a hypothesis that carvedilol analogue may also prevent triggered activities (TAs) through the suppression of early afterdepolarizations (EADs). Intracellular Ca(2+) and membrane voltage were simultaneously recorded by using optical mapping technique in Langendorff-perfused mouse and rabbit hearts to study the effect of carvedilol analogue VK-II-36, which does not have significant beta-blocking effects. Spontaneous intracellular Ca(2+) elevations (SCaEs) during diastole were induced by rapid ventricular pacing and isoproterenol infusion in intact rabbit ventricles. Systolic and diastolic SCaEs were simultaneously noted in Langendorff-perfused RyR2 R4496(+/-) mouse hearts after creating atrioventricular block. VK-II-36 effectively suppressed SCaEs and eliminated TAs observed in both mouse and rabbit ventricles. We tested the effect of VK-II-36 on EADs by using a rabbit model of acquired long QT syndrome, in which phase 2 and phase 3 EADs were observed in association with systolic SCaEs. VK-II-36 abolished the systolic SCaEs and phase 2 EADs, and greatly decreased the dispersion of repolarization and the amplitude of phase 3 EADs. VK-II-36 completely prevented EAD-mediated TAs in all ventricles studied. A carvedilol analogue, VK-II-36, inhibits ventricular tachyarrhythmias in intact mouse and rabbit ventricles by the suppression of SCaEs, independent of beta-blocking activity. The RyR2 may be a potential target for treating focal ventricular arrhythmias triggered by either EADs or DADs. Copyright © 2013 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

Electroantennographic and behavioral responses of the sphinx moth Manduca sexta to host plant headspace volatiles.

PubMed

Fraser, Ann M; Mechaber, Wendy L; Hildebrand, John G

2003-08-01

Coupled gas chromatography with electroantennographic detection (GC-EAD) using antennae of adult female Manduca sexta was employed to screen for olfactory stimulants present in headspace collections from four species of larval host plants belonging to two families: Solanaceae--Lycopersicon esculentum (tomato), Capiscum annuum (bell pepper), and Datura wrightii; and Martyniaceae--Pronboscideaparviflora. Headspace volatiles were collected from undamaged foliage of potted, living plants. GC-EAD revealed 23 EAD-active compounds, of which 15 were identified by GC-mass spectrometry. Identified compounds included aliphatic, aromatic, and terpenoid compounds bearing a range of functional groups. Nine EAD-active compounds were common to all four host plant species: (Z)-3-hexenyl acetate, nonanal, decanal, phenylacetaldehyde, methyl salicylate, benzyl alcohol, geranyl acetone, (E)-nerolidol, and one unidentified compound. Behavioral responses of female moths to an eight-component synthetic blend of selected tomato headspace volatiles were tested in a laboratory wind tunnel. Females were attracted to the blend. A comparison of responses from antennae of males and females to bell pepper headspace volatiles revealed that males responded to the same suite of volatiles as females, except for (Z)-3-hexenyl benzoate. EAD responses of males also were lower for (Z)-and (E)-nerolidol and one unidentified compound. Electroantennogram EAG dose-response curves for the 15 identified EAD-active volatiles were recorded. At the higher test doses (10-100 microg), female antennae yielded larger EAG responses to terpenoids and to aliphatic and aromatic esters. Male antennae did respond to the higher doses of (Z)-3-hexenyl benzoate, indicating that they can detect this compound. On the basis of ubiquity of the EAD-active volatiles identified to date in host plant headspace collections, we suggest that M. sexta uses a suite of volatiles to locate and identify appropriate host plants.

Atmospheric numerical modeling resource enhancement and model convective parameterization/scale interaction studies

NASA Technical Reports Server (NTRS)

Cushman, Paula P.

1993-01-01

Research will be undertaken in this contract in the area of Modeling Resource and Facilities Enhancement to include computer, technical and educational support to NASA investigators to facilitate model implementation, execution and analysis of output; to provide facilities linking USRA and the NASA/EADS Computer System as well as resident work stations in ESAD; and to provide a centralized location for documentation, archival and dissemination of modeling information pertaining to NASA's program. Additional research will be undertaken in the area of Numerical Model Scale Interaction/Convective Parameterization Studies to include implementation of the comparison of cloud and rain systems and convective-scale processes between the model simulations and what was observed; and to incorporate the findings of these and related research findings in at least two refereed journal articles.

Subject Access Points in the MARC Record and Archival Finding Aid: Enough or Too Many?

ERIC Educational Resources Information Center

Cox, Elizabeth; Czechowski, Leslie

2007-01-01

In this research project, the authors set out to discover the current practice in both the archival and cataloging worlds for usage of access points in descriptive records and to learn how archival descriptive practices fit into long-established library cataloging procedures and practices. A sample of archival finding aids and MARC records at 123…

A Novel Method for In Situ Electromechanical Characterization of Nanoscale Specimens

PubMed Central

Reid, Russell C.; Piqué, Alberto; Kang, Wonmo

2017-01-01

Electrically assisted deformation (EAD) is increasingly being used to improve the formability of metals during processes such as sheet metal rolling and forging. Adoption of this technique is proceeding despite disagreement concerning the underlying mechanism responsible for EAD. The experimental procedure described herein enables a more explicit study compared to previous EAD research by removing thermal effects, which are responsible for disagreement in interpreting previous EAD results. Furthermore, as the procedure described here enables EAD observation in situ and in real time in a transmission electron microscope (TEM), it is superior to existing post-mortem methods that observe EAD effects post-test. Test samples consist of a single crystal copper (SCC) foil having a free-standing tensile test section of nanoscale thickness, fabricated using a combination of laser and ion beam milling. The SCC is mounted to an etched silicon base that provides mechanical support and electrical isolation while serving as a heat sink. Using this geometry, even at high current density (~3,500 A/mm2), the test section experiences a negligible temperature increase (<0.02 °C), thus eliminating Joule heating effects. Monitoring material deformation and identifying the corresponding changes to microstructures, e.g. dislocations, are accomplished by acquiring and analyzing a series of TEM images. Our sample preparation and in situ experiment procedures are robust and versatile as they can be readily utilized to test materials with different microstructures, e.g., single and polycrystalline copper. PMID:28605394

The Archival Photograph and Its Meaning: Formalisms for Modeling Images

ERIC Educational Resources Information Center

Benson, Allen C.

2009-01-01

This article explores ontological principles and their potential applications in the formal description of archival photographs. Current archival descriptive practices are reviewed and the larger question is addressed: do archivists who are engaged in describing photographs need a more formalized system of representation, or do existing encoding…

ISER - Energy Assurance Daily (EAD)

Science.gov Websites

can search online for information and the availability of free customizable news alerts, the EAD is section of the OE website. Download the free adobe acrobat reader to view PDFs You will need the Adobe

Theoretical Study on Nano-Catalyst Burn Rate

DTIC Science & Technology

2014-11-26

the adsorbed system EAP +surface and the adsorption state, with a positive value of Eads being thermodynamically favorable: Eads = (Esurface + EAP ... EAP +surface, (1) The interaction between the TiO2 surfaces and the AP molecules has been analyzed by

Mutations of amino acids in the DNA-recognition domain of Epstein-Barr virus ZEBRA protein alter its sub-nuclear localization and affect formation of replication compartments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Park, Richard; Heston, Lee; Shedd, Duane

ZEBRA, a transcription factor and DNA replication protein encoded by the Epstein-Barr virus (EBV) BZLF1 gene, plays indispensable roles in the EBV lytic cycle. We recently described the phenotypes of 46 single amino acid substitutions introduced into the DNA-recognition region of ZEBRA [Heston, L., El-Guindy, A., Countryman, J., Dela Cruz, C., Delecluse, H.J., and Miller, G. 2006]. The 27 DNA-binding-proficient mutants exhibited distinct defects in their ability to activate expression of the kinetic classes of viral genes. Four phenotypic variants could be discerned: wild-type, defective at activating Rta, defective at activating early genes, and defective at activating late genes. Heremore » we analyze the distribution of ZEBRA within the nucleus and the localization of EA-D (the viral DNA polymerase processivity factor), an indicator of the development of replication compartments, in representatives of each phenotypic group. Plasmids encoding wild-type (WT) and mutant ZEBRA were transfected into 293 cells containing EBV-bacmids. WT ZEBRA protein was diffusely and smoothly distributed throughout the nucleus, sparing nucleoli, and partially recruited to globular replication compartments. EA-D induced by WT ZEBRA was present diffusely in some cells and concentrated in globular replication compartments in other cells. The distribution of ZEBRA and EA-D proteins was identical to WT following transfection of K188R, a mutant with a conservative change. The distribution of S186A mutant ZEBRA protein, defective for activation of Rta and EA-D, was identical to WT, except that the mutant ZEBRA was never found in globular compartments. Co-expression of Rta with S186A mutant rescued diffuse EA-D but not globular replication compartments. The most striking observation was that several mutant ZEBRA proteins defective in activating EA-D (R179A, K181A and A185V) and defective in activating lytic viral DNA replication and late genes (Y180E and K188A) were localized to numerous punctate foci. The speckled appearance of R179A and Y180E was more regular and clearly defined in EBV-positive than in EBV-negative 293 cells. The Y180E late-mutant induced EA-D, but prevented EA-D from localizing to globular replication compartments. These results show that individual amino acids within the basic domain influence localization of the ZEBRA protein and its capacity to induce EA-D to become located in mature viral replication compartments. Furthermore, these mutant ZEBRA proteins delineate several stages in the processes of nuclear re-organization which accompany lytic EBV replication.« less

Concerning Descriptive Standards: A Partnership between Public Archives and Private Collections in Geneva, Switzerland

ERIC Educational Resources Information Center

Roth-Lochner, Barbara; Grange, Didier

2005-01-01

This paper presents the results of a partnership begun in 2002 in the field of archival description between the Geneva City Archives (AVG) and the Manuscripts Department of the Public and University Library of Geneva (BPU). This cooperation has allowed the creation of two computer applications, which share technical and conceptual foundations.…

Effects of temperature and heat waves on emergency department visits and emergency ambulance dispatches in Pudong New Area, China: a time series analysis.

PubMed

Sun, Xiaoming; Sun, Qiao; Yang, Minjuan; Zhou, Xianfeng; Li, Xiaopan; Yu, Aiqing; Geng, Fuhai; Guo, Yuming

2014-10-02

In July 2013, an extended heat episode with extreme high temperature covered Pudong New Area, the largest district in Shanghai. The current study estimates the impacts of temperature and heat waves on emergency department visits (EDV) and emergency ambulance dispatches (EAD) using time-series approaches in Pudong, from 2011 to 2013. An over-dispersed Poisson generalized additive model was used to examine the association between temperature and EDV and EAD. Heat wave effects with different heat wave definitions considering both the intensity and durations were also estimated. Immediate effects of temperature on EDV and EAD were detected, after controlling for trends of time and day of week. The exposure-response relationships showed J-shaped curves with higher threshold temperature of EDV than that of EAD visually. When estimating risk changes on heat days compared with non-heat days using different percentiles of daily mean temperature in definition, EAD showed significant increases while non-significant or even negative associations were found for EDV. Heat wave with intensity above the 90th percentile had 2.62% (95% CI: 1.78%, 3.46%) and 0.95% (95% CI: 0.22%, 1.69%) increases in EDV for a duration of at least 2 days and 3 days respectively. The relative increase of EAD were 4.85% (95% CI: 1.42%, 8.39%) and 3.94% (95% CI: 0.88%, 7.10%). Varied effects of temperature and heat waves on emergency department visits and emergency ambulance dispatches were investigated. This wider view of the health effect of temperature indicated that interventions for both public health education and health services management should be considered in the study region.

The combination of indocyanine green clearance test and model for end-stage liver disease score predicts early graft outcome after liver transplantation.

PubMed

Yunhua, Tang; Weiqiang, Ju; Maogen, Chen; Sai, Yang; Zhiheng, Zhang; Dongping, Wang; Zhiyong, Guo; Xiaoshun, He

2018-06-01

Early allograft dysfunction (EAD) and early postoperative complications are two important clinical endpoints when evaluating clinical outcomes of liver transplantation (LT). We developed and validated two ICGR15-MELD models in 87 liver transplant recipients for predicting EAD and early postoperative complications after LT by incorporating the quantitative liver function tests (ICGR15) into the MELD score. Eighty seven consecutive patients who underwent LT were collected and divided into a training cohort (n = 61) and an internal validation cohort (n = 26). For predicting EAD after LT, the area under curve (AUC) for ICGR15-MELD score was 0.876, with a sensitivity of 92.0% and a specificity of 75.0%, which is better than MELD score or ICGR15 alone. The recipients with a ICGR15-MELD score ≥0.243 have a higher incidence of EAD than those with a ICGR15-MELD score <0.243 (P <0.001). For predicting early postoperative complications, the AUC of ICGR15-MELD score was 0.832, with a sensitivity of 90.9% and a specificity of 71.0%. Those recipients with an ICGR15-MELD score ≥0.098 have a higher incidence of early postoperative complications than those with an ICGR15-MELD score <0.098 (P < 0.001). Finally, application of the two ICGR15-MELD models in the validation cohort still gave good accuracy (AUC, 0.835 and 0.826, respectively) in predicting EAD and early postoperative complications after LT. The combination of quantitative liver function tests (ICGR15) and the preoperative MELD score is a reliable and effective predictor of EAD and early postoperative complications after LT, which is better than MELD score or ICGR15 alone.

Distinguishing neurocognitive deficits in adult patients with NP-C from early onset Alzheimer's dementia.

PubMed

Johnen, Andreas; Pawlowski, Matthias; Duning, Thomas

2018-06-05

Niemann-Pick disease type C (NP-C) is a rare, progressive neurodegenerative disease caused by mutations in the NPC1 or the NPC2 gene. Neurocognitive deficits are common in NP-C, particularly in patients with the adolescent/adult-onset form. As a disease-specific therapy is available, it is important to distinguish clinically between the cognitive profiles in NP-C and primary dementia (e.g., early Alzheimer's disease; eAD). In a prospective observational study, we directly compared the neurocognitive profiles of patients with confirmed NP-C (n = 7) and eAD (n = 15). All patients underwent neurocognitive assessment using dementia screening tests (mini-mental status examination [MMSE] and frontal assessment battery [FAB]) and an extensive battery of tests assessing verbal memory, visuoconstructive abilities, visual memory, executive functions and verbal fluency. Overall cognitive impairment (MMSE) was significantly greater in eAD vs. NP-C (p = 0.010). The frequency of patients classified as cognitively 'impaired' was also significantly greater in eAD vs. NP-C (p = 0.025). Patients with NP-C showed relatively preserved verbal memory, but frequent impairment in visual memory, visuoconstruction, executive functions and in particular, verbal fluency. In the eAD group, a wider profile of more frequent and more severe neurocognitive deficits was seen, primarily featuring severe verbal and visual memory deficits along with major executive impairment. Delayed verbal memory recall was a particularly strong distinguishing factor between the two groups. A combination of detailed yet easy-to-apply neurocognitive tests assessing verbal memory, executive functions and verbal fluency may help distinguish NP-C cases from those with primary dementia due to eAD.

29 CFR 4041.45 - Distress termination notice.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., Single-Employer Plan Termination, with Schedule EA-D, Distress Termination Enrolled Actuary Certification... guaranteed benefits. Unless the enrolled actuary certifies, in the Schedule EA-D filed in accordance with... benefits or benefit liabilities. If the enrolled actuary certifies that the plan is sufficient either for...

29 CFR 4041.45 - Distress termination notice.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., Single-Employer Plan Termination, with Schedule EA-D, Distress Termination Enrolled Actuary Certification... guaranteed benefits. Unless the enrolled actuary certifies, in the Schedule EA-D filed in accordance with... benefits or benefit liabilities. If the enrolled actuary certifies that the plan is sufficient either for...

29 CFR 4041.45 - Distress termination notice.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., Single-Employer Plan Termination, with Schedule EA-D, Distress Termination Enrolled Actuary Certification... guaranteed benefits. Unless the enrolled actuary certifies, in the Schedule EA-D filed in accordance with... benefits or benefit liabilities. If the enrolled actuary certifies that the plan is sufficient either for...

29 CFR 4041.45 - Distress termination notice.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., Single-Employer Plan Termination, with Schedule EA-D, Distress Termination Enrolled Actuary Certification... guaranteed benefits. Unless the enrolled actuary certifies, in the Schedule EA-D filed in accordance with... benefits or benefit liabilities. If the enrolled actuary certifies that the plan is sufficient either for...

29 CFR 4041.45 - Distress termination notice.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., Single-Employer Plan Termination, with Schedule EA-D, Distress Termination Enrolled Actuary Certification... guaranteed benefits. Unless the enrolled actuary certifies, in the Schedule EA-D filed in accordance with... benefits or benefit liabilities. If the enrolled actuary certifies that the plan is sufficient either for...

On Elementary Affective Decisions: To Like Or Not to Like, That Is the Question

PubMed Central

Jacobs, Arthur; Hofmann, Markus J.; Kinder, Annette

2016-01-01

Perhaps the most ubiquitous and basic affective decision of daily life is deciding whether we like or dislike something/somebody, or, in terms of psychological emotion theories, whether the object/subject has positive or negative valence. Indeed, people constantly make such liking decisions within a glimpse and, importantly, often without expecting any obvious benefit or knowing the exact reasons for their judgment. In this paper, we review research on such elementary affective decisions (EADs) that entail no direct overt reward with a special focus on Neurocognitive Poetics and discuss methods and models for investigating the neuronal and cognitive-affective bases of EADs to verbal materials with differing degrees of complexity. In line with evolutionary and appraisal theories of (aesthetic) emotions and data from recent neurocognitive studies, the results of a decision tree modeling approach simulating EADs to single words suggest that a main driving force behind EADs is the extent to which such high-dimensional stimuli are associated with the “basic” emotions joy/happiness and disgust. PMID:27933013

Evaluation of Anthelmintic Resistance and Exhaust Air Dust PCR as a Diagnostic Tool in Mice Enzootically Infected with Aspiculuris tetraptera

PubMed Central

Kapoor, Pratibha; Hayes, Yumiko O; Jarrell, Leslie T; Bellinger, Dwight A; Thomas, Rhiannon D; Lawson, Gregory W; Arkema, Jaclyn D; Fletcher, Craig A; Nielsen, Judith N

2017-01-01

The entry of infectious agents in rodent colonies occurs despite robust sentinel monitoring programs, strict quarantine measures, and stringent biosecurity practices. In light of several outbreaks with Aspiculuris tetraptera in our facilities, we investigated the presence of anthelmintic resistance and the use of exhaust air dust (EAD) PCR for early detection of A. tetraptera infection. To determine anthelmintic resistance, C57BL/6, DBA/2, and NCr nude mice were experimentally inoculated with embryonated A. tetraptera ova harvested from enzootically infected mice, followed by treatment with 150 ppm fenbendazole in feed, 150 ppm fenbendazole plus 5 ppm piperazine in feed, or 2.1 mg/mL piperazine in water for 4 or 8 wk. Regardless of the mouse strain or treatment, no A. tetraptera were recovered at necropsy, indicating the lack of resistance in the worms to anthelmintic treatment. In addition, 10 of 12 DBA/2 positive-control mice cleared the A. tetraptera infection without treatment. To evaluate the feasibility of EAD PCR for A. tetraptera, 69 cages of breeder mice enzootically infected with A. tetraptera were housed on a Tecniplast IVC rack as a field study. On day 0, 56% to 58% of the cages on this rack tested positive for A. tetraptera by PCR and fecal centrifugation flotation (FCF). PCR from EAD swabs became positive for A. tetraptera DNA within 1 wk of placing the above cages on the rack. When these mice were treated with 150 ppm fenbendazole in feed, EAD PCR reverted to pinworm-negative after 1 mo of treatment and remained negative for an additional 8 wk. The ability of EAD PCR to detect few A. tetraptera positive mice was investigated by housing only 6 infected mice on another IVC rack as a field study. The EAD PCR from this rack was positive for A. tetraptera DNA within 1 wk of placing the positive mice on it. These findings demonstrate that fenbendazole is still an effective anthelmintic and that EAD PCR is a rapid, noninvasive assay that may be a useful diagnostic tool for antemortem detection of A. tetraptera infection, in conjunction with fecal PCR and FCF. PMID:28535863

ELECTRICAL AEROSOL DETECTOR (EAD) MEASUREMENTS AT THE ST. LOUIS SUPERSITE

EPA Science Inventory

The Model 3070A Electrical Aerosol Detector (EAD) measures a unique aerosol parameter called total aerosol length. Reported as mm/cm3, aerosol length can be thought of as a number concentration times average diameter, or simply as d1 weighting. This measurement falls between nu...

Distraction, Compression, Extension, and Reduction Combined With Joint Remodeling and Extra-articular Distraction: Description of 2 New Modifications for Its Application in Basilar Invagination and Atlantoaxial Dislocation: Prospective Study in 79 Cases.

PubMed

Chandra, P Sarat; Prabhu, Manik; Goyal, Nishant; Garg, Ajay; Chauhan, Avnish; Sharma, Bhawani Shankar

2015-07-01

Recent strategies for treatment of basilar invagination (BI) and atlantoaxial dislocation (AAD) are based on simultaneous posterior reduction and fixation. To describe new modifications of the procedure distraction, compression, extension, and reduction (DCER), ie, joint remodeling (JRM) and extra-articular distraction (EAD) in patients with "vertical" joints, and to quantify the improvement in joint indices, ie, sagittal inclination (SI), craniocervical tilt (CCT), and coronal inclination. Prospective study (May 2010 to September 2014). Joint indices measured included (normal values): SI (87.15 ± 5.65°), CCT (60.2 ± 9.2°), and coronal inclination (110.3 ± 4.23°). Surgical procedures included DCER alone (performed in SI <100°, group I) or JRM with DCER (in SI: 100-160°, group II), or EAD with DCER in severe BI with almost vertical joints (SI >160°, group III). Seventy-nine patients were selected (mean, 22.5 years of age). All conventional indices improved significantly (P < .001). CCT improved in all groups (P < .01); group I (n = 32): 54 ± 8.7° (preoperative 80.71 ± 12.72°); group II (n = 40): 58 ± 7.0° (preoperative 86.5 ± 14°); group III (n = 7): 62 ± 10.0° (preoperative 104 ± 11.2°). SI improved in both group I and II, P < .01 (cannot be measured in group III). At long-term follow-up (n = 64, 29 ± 8 months, range 12-39 months), the Nurick grade improved to 1.5 ± 0.52 (preoperative: 3.4 ± 0.65; P < .001). DCER seems to be an effective technique in reducing both BI and AAD. JRM and EAD with DCER are useful in moderate to severe BI and AAD (with SI >100°). Joint indices provide useful information for surgical strategy and planning.

Identification by GC-EAD of the two-component trail-following pheromone of Prorhinotermes simplex (Isoptera, Rhinotermitidae, Prorhinotermitinae).

PubMed

Sillam-Dussès, David; Kalinová, Blanka; Jiros, Pavel; Brezinová, Anna; Cvacka, Josef; Hanus, Robert; Sobotník, Jan; Bordereau, Christian; Valterová, Irena

2009-08-01

GC/MS analysis confirmed that neocembrene is the major component of the trail pheromone in the three species of the termite genus Prorhinotermes (P. simplex, P. canalifrons, P. inopinatus). In addition, EAG and GC-EAD experiments with P. simplex strongly suggest that dodecatrienol is a quantitatively minor component but a qualitatively important component of this trail pheromone. Trail-following bioassays confirmed the two-component nature of the trail pheromone. This is the first report of the use of the GC-EAD for the identification of trail pheromone in termites. These original results underline once again the special phylogenetic status of the Prorhinotermitinae among Rhinotermitidae.

78 FR 7262 - Airworthiness Directives; EADS CASA (Type Certificate Previously Held by Construcciones...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-01

... Airworthiness Directives; EADS CASA (Type Certificate Previously Held by Construcciones Aeron[aacute]uticas, S.A... Certificate previously held by Construcciones Aeron[aacute]uticas, S.A.) Model CN-235, CN-235-100, CN-235-200... Certificate previously held by Construcciones Aeron[aacute]uticas, S.A.): Amendment 39- [[Page 7264

An automated approach to detecting signals in electroantennogram data

Treesearch

D.H. Slone; B.T. Sullivan

2007-01-01

Coupled gas chromatography/electroantennographic detection (GC-EAD) is a widely used method for identifying insect olfactory stimulants present in mixtures of volatiles, and it can greatly accelerate the identification of insect semiochemicals. In GC-EAD, voltage changes across an insect's antenna are measured while the antenna is exposed to compounds eluting fi-...

Response of the small hive beetle (Aethina tumida) to a blend of chemicals identified from honeybee (Apis mellifera) volatiles

USDA-ARS?s Scientific Manuscript database

Coupled gas chromatographic-electroantennographic detection (GC-EAD) analyses of Super Q collected worker honey bee volatiles revealed several components that elicited antennal responses by the small hive beetle Aethina tumida. However, GC-MS analysis showed that eight of these EAD-active components...

Development of a host-based semiochemical lure for trapping emerald ash borer (Agrilus planipennis (Coleoptera: Buprestidae)

Treesearch

Damon J. Crook; Ashot Khrimian; Joseph A. Francese; Ivich Fraser; Therese M. Poland; Alan J. Sawyer; Victor C. Mastro

2008-01-01

Bark volatiles from green ash Fraxinus pennsylvanica were tested for electrophysiological activity by Agrilus planipennis using gas chromatographic-electroantennographic detection (GC-EAD) and for behavioral activity using baited purple traps in Michigan. GC-EAD analysis of the headspace volatiles of bark tissue samples from 0...

A Comparison of Descriptive Tagging Practices by Library, Archive and Museum Professionals Using an Inter-Indexing Consistency Approach

ERIC Educational Resources Information Center

Angel, Christine Marie

2012-01-01

This study is a comparison of the descriptive tagging practices among library, archive, and museum professionals using an inter-indexing consistency approach. The first purpose of this study was to determine the extent of the similarities and differences among professional groups when assigning descriptive tags to a wide variety of objects that…

Performance of the engineering analysis and data system 2 common file system

NASA Technical Reports Server (NTRS)

Debrunner, Linda S.

1993-01-01

The Engineering Analysis and Data System (EADS) was used from April 1986 to July 1993 to support large scale scientific and engineering computation (e.g. computational fluid dynamics) at Marshall Space Flight Center. The need for an updated system resulted in a RFP in June 1991, after which a contract was awarded to Cray Grumman. EADS II was installed in February 1993, and by July 1993 most users were migrated. EADS II is a network of heterogeneous computer systems supporting scientific and engineering applications. The Common File System (CFS) is a key component of this system. The CFS provides a seamless, integrated environment to the users of EADS II including both disk and tape storage. UniTree software is used to implement this hierarchical storage management system. The performance of the CFS suffered during the early months of the production system. Several of the performance problems were traced to software bugs which have been corrected. Other problems were associated with hardware. However, the use of NFS in UniTree UCFM software limits the performance of the system. The performance issues related to the CFS have led to a need to develop a greater understanding of the CFS organization. This paper will first describe the EADS II with emphasis on the CFS. Then, a discussion of mass storage systems will be presented, and methods of measuring the performance of the Common File System will be outlined. Finally, areas for further study will be identified and conclusions will be drawn.

Use of FDSS/μCell imaging platform for preclinical cardiac electrophysiology safety screening of compounds in human induced pluripotent stem cell-derived cardiomyocytes.

PubMed

Zeng, Haoyu; Roman, Maria I; Lis, Edward; Lagrutta, Armando; Sannajust, Frederick

2016-01-01

FDSS/μCell is a high-speed acquisition imaging platform (Hamamatsu Ltd., Hamamatsu, Japan) that allows for simultaneous high-throughput reading under controlled conditions. We evaluated the Ca(2+) transients or optical membrane potential changes of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) (iCells) in the presence or absence of 44 pharmacological agents known to interfere with cardiac ion channels (e.g., hERG, IKs, NaV1.5, CaV1.2). We tested two Ca(2+)-sensitive fluorescence dyes (Codex ACTOne® and EarlyTox®) and a membrane potential dye (FLIPR® membrane potential dye). We were able to quantify and report drug-induced early-after depolarizations (EAD)-like waveforms, cardiomyocyte ectopic beats and changes in beating rate from a subgroup of pharmacological agents acting acutely (within a 1-hour period). Cardiovascular drugs, such as dofetilide and d,l-sotalol, exhibited EAD-like signals at 3nM and 10μM, respectively. CNS drugs, such as haloperidol and sertindole, exhibited EAD-like signals and ectopic beats at 30nM and 1μM, respectively. Other drugs, such as astemizole, solifenacin, and moxifloxacin, exhibited similar arrhythmias at 30nM, 3μM and 300μM, respectively. Our data suggest that the membrane potential and intracellular Ca(2+) signal are tightly coupled, supporting the idea that the EAD-like signals reported are the accurate representation of an EAD signal of the cardiac action potential. Finally, the EAD-like Ca(2+) signal was well correlated to clinically-relevant concentrations where Torsade de Pointes (TdPs) arrhythmias were noted in healthy volunteers treated orally with some of the compounds we tested, as reported in PharmaPendium®. Copyright © 2016 Elsevier Inc. All rights reserved.

A score model for the continuous grading of early allograft dysfunction severity.

PubMed

Pareja, Eugenia; Cortes, Miriam; Hervás, David; Mir, José; Valdivieso, Andrés; Castell, José V; Lahoz, Agustín

2015-01-01

Early allograft dysfunction (EAD) dramatically influences graft and patient outcomes. A lack of consensus on an EAD definition hinders comparisons of liver transplant outcomes and management of recipients among and within centers. We sought to develop a model for the quantitative assessment of early allograft function [Model for Early Allograft Function Scoring (MEAF)] after transplantation. A retrospective study including 1026 consecutive liver transplants was performed for MEAF score development. Multivariate data analysis was used to select a small number of postoperative variables that adequately describe EAD. Then, the distribution of these variables was mathematically modeled to assign a score for each actual variable value. A model, based on easily obtainable clinical parameters (ie, alanine aminotransferase, international normalized ratio, and bilirubin) and scoring liver function from 0 to 10, was built. The MEAF score showed a significant association with patient and graft survival at 3-, 6- and 12-month follow-ups. Hepatic steatosis and age for donors; cold/warm ischemia times and postreperfusion syndrome for surgery; and intensive care unit and hospital stays, Model for End-Stage Liver Disease and Child-Pugh scores, body mass index, and fresh frozen plasma transfusions for recipients were factors associated significantly with EAD. The model was satisfactorily validated by its application to an independent set of 200 patients who underwent liver transplantation at a different center. In conclusion, a model for the quantitative assessment of EAD severity has been developed and validated for the first time. The MEAF provides a more accurate graft function assessment than current categorical classifications and may help clinicians to make early enough decisions on retransplantation benefits. Furthermore, the MEAF score is a predictor of recipient and graft survival. The standardization of the criteria used to define EAD may allow reliable comparisons of recipients' treatments and transplant outcomes among and within centers. © 2014 American Association for the Study of Liver Diseases.

Europe’s New Defense Ambitions: Implications for NATO, the US, and Russia

DTIC Science & Technology

2000-04-01

of Moscow’s current constructive attitude is equally unlikely, because its economic and trade ties with the EU region are too valuable for Russia to...19. The Spanish Construcciones Aeronáuticas S. A. (CASA) aerospace group joined the EADS in December 1999. EADS now controls 80 per cent of the

Online Finding Aids with BASYS-Fox in the Bundesarchiv, Germany

ERIC Educational Resources Information Center

Sander, Oliver

2005-01-01

This article discusses the process for the production of online finding aids with BASYS-Fox system and it describes the scope of application of EAD in the Bundesarchiv. In 2000, the project "Presentation of Online Finding Aids with the EAD system" was started at Bundesarchiv. The project was promoted by the German Science Foundation…

Exhaust Air Dust Monitoring is Superior to Soiled Bedding Sentinels for the Detection of Pasteurella pneumotropica in Individually Ventilated Cage Systems.

PubMed

Miller, Manuel; Ritter, Brbel; Zorn, Julia; Brielmeier, Markus

2016-11-01

Reliable detection of unwanted organisms is essential for meaningful health monitoring in experimental animal facilities. Currently, most rodents are housed in IVC systems, which prevent the aerogenic transmission of pathogens between cages. Typically soiled-bedding sentinels (SBS) exposed to soiled bedding collected from a population of animals within an IVC rack are tested as representatives, but infectious agents often go undetected due to inefficient transmission. Pasteurellaceae are among the most prevalent bacterial pathogens isolated from experimental mice, and the failure of SBS to detect these bacteria is well established. In this study, we investigated whether analysis of exhaust air dust (EAD) samples by using a sensitive and specific real-time PCR assay is superior to conventional SBS monitoring for the detection of Pasteurella pneumotropica (Pp) infections. In a rack with a known prevalence of Pp-positive mice, weekly EAD sampling was compared with the classic SBS method over 3 mo. In 6 rounds of testing, with a prevalence of 5 infected mice in each of 7 cages in a rack of 63 cages, EAD PCR detected Pp at every weekly time point; SBS failed to detect Pp in all cases. The minimal prevalence of Pp-infected mice required to obtain a reliable positive result by EAD PCR testing was determined to be 1 in 63 cages. Reliable detection of Pp was achieved after only 1 wk of exposure. Analysis of EAD samples by real-time PCR assay provides a sensitive, simple, and reliable approach for Pp identification in laboratory mice.

Exhaust Air Dust Monitoring is Superior to Soiled Bedding Sentinels for the Detection of Pasteurella pneumotropica in Individually Ventilated Cage Systems

PubMed Central

Miller, Manuel; Ritter, Bärbel; Zorn, Julia; Brielmeier, Markus

2016-01-01

Reliable detection of unwanted organisms is essential for meaningful health monitoring in experimental animal facilities. Currently, most rodents are housed in IVC systems, which prevent the aerogenic transmission of pathogens between cages. Typically soiled-bedding sentinels (SBS) exposed to soiled bedding collected from a population of animals within an IVC rack are tested as representatives, but infectious agents often go undetected due to inefficient transmission. Pasteurellaceae are among the most prevalent bacterial pathogens isolated from experimental mice, and the failure of SBS to detect these bacteria is well established. In this study, we investigated whether analysis of exhaust air dust (EAD) samples by using a sensitive and specific real-time PCR assay is superior to conventional SBS monitoring for the detection of Pasteurella pneumotropica (Pp) infections. In a rack with a known prevalence of Pp-positive mice, weekly EAD sampling was compared with the classic SBS method over 3 mo. In 6 rounds of testing, with a prevalence of 5 infected mice in each of 7 cages in a rack of 63 cages, EAD PCR detected Pp at every weekly time point; SBS failed to detect Pp in all cases. The minimal prevalence of Pp-infected mice required to obtain a reliable positive result by EAD PCR testing was determined to be 1 in 63 cages. Reliable detection of Pp was achieved after only 1 wk of exposure. Analysis of EAD samples by real-time PCR assay provides a sensitive, simple, and reliable approach for Pp identification in laboratory mice. PMID:27931316

Cingulum correlates of cognitive functions in patients with mild cognitive impairment and early Alzheimer's disease: a diffusion spectrum imaging study.

PubMed

Lin, Yi-Cheng; Shih, Yao-Chia; Tseng, Wen-Yih I; Chu, Yu-Hsiu; Wu, Meng-Tien; Chen, Ta-Fu; Tang, Pei-Fang; Chiu, Ming-Jang

2014-05-01

Diffusion spectrum imaging (DSI) of MRI can detect neural fiber tract changes. We investigated integrity of cingulum bundle (CB) in patients with mild cognitive impairment (MCI) and early Alzheimer's disease (EAD) using DSI tractography and explored its relationship with cognitive functions. We recruited 8 patients with MCI, 9 with EAD and 15 healthy controls (HC). All subjects received a battery of neuropsychological tests to access their executive, memory and language functions. We used a 3.0-tesla MRI scanner to obtain T1- and T2-weighted images for anatomy and used a pulsed gradient twice-refocused spin-echo diffusion echo-planar imaging sequence to acquire DSI. Patients with EAD performed significantly poorer than the HC on most tests in executive and memory functions. Significantly smaller general fractional anisotropy (GFA) values were found in the posterior and inferior segments of left CB and of the anterior segment of right CB of the EAD compared with those of the HC. Spearman's correlation on the patient groups showed that GFA values of the posterior segment of the left CB were significantly negatively associated with the time used to complete Color Trails Test Part II and positively correlated with performance of the logical memory and visual reproduction. GFA values of inferior segment of bilateral CB were positively associated with the performance of visual recognition. DSI tractography demonstrates significant preferential degeneration of the CB on the left side in patients with EAD. The location-specific degeneration is associated with corresponding declines in both executive and memory functions.

Metabolomics discloses donor liver biomarkers associated with early allograft dysfunction.

PubMed

Cortes, Miriam; Pareja, Eugenia; García-Cañaveras, Juan C; Donato, M Teresa; Montero, Sandra; Mir, Jose; Castell, José V; Lahoz, Agustín

2014-09-01

Early allograft dysfunction (EAD) dramatically influences graft and patient outcome after orthotopic liver transplantation and its incidence is strongly determined by donor liver quality. Nevertheless, objective biomarkers, which can assess graft quality and anticipate organ function, are still lacking. This study aims to investigate whether there is a preoperative donor liver metabolomic biosignature associated with EAD. A comprehensive metabolomic profiling of 124 donor liver biopsies collected before transplantation was performed by mass spectrometry coupled to liquid chromatography. Donor liver grafts were classified into two groups: showing EAD and immediate graft function (IGF). Multivariate data analysis was used to search for the relationship between the metabolomic profiles present in donor livers before transplantation and their function in recipients. A set of liver graft dysfunction-associated biomarkers was identified. Key changes include significantly increased levels of bile acids, lysophospholipids, phospholipids, sphingomyelins and histidine metabolism products, all suggestive of disrupted lipid homeostasis and altered histidine pathway. Based on these biomarkers, a predictive EAD model was built and further evaluated by assessing 24 independent donor livers, yielding 91% sensitivity and 82% specificity. The model was also successfully challenged by evaluating donor livers showing primary non-function (n=4). A metabolomic biosignature that accurately differentiates donor livers, which later showed EAD or IGF, has been deciphered. The remarkable metabolomic differences between donor livers before transplant can relate to their different quality. The proposed metabolomic approach may become a clinical tool for donor liver quality assessment and for anticipating graft function before transplant. Copyright © 2014 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

Application of electro acoustics for dewatering pharmaceutical sludge

DOE Office of Scientific and Technical Information (OSTI.GOV)

Golla, P.S.; Johnson, H.W.

1992-02-01

Application of electro acoustic principles for dewatering has been developed by Battelle Institute. The Department of Energy, Battelle Institute, and Ashbrook-Simon-Hartley, have jointly developed an Electro Acoustic Dewatering press (EAD press). The EAD press applies a combination of mechanical pressure, electrical current and ultrasonics. This press is utilized after conventional dewatering devices and can remove up to 50% water from filtered sludge cake at a fraction of the cost incurred in existing thermal drying devices. The dominant mechanism of sludge dewatering by EAD press is electro-osmosis due to the application of a direct current field. Electro-osmosis is caused by anmore » electrical double layer of oppositely charged ions formed at the solid liquid interface, which is characterized by zeta potential. The ultrasonic fields help electro-osmosis by consolidation of the filter cake and by release of inaccessible liquid. The EAD press has been tested successfully on a variety of materials including apple pomace, corn gluten, sewage sludge, and coal fines. A three week long full scale trial was conducted successfully at a pharmaceutical industry to determine the application of this technology for dewatering waste activated sludge.« less

Environmental implications of anaerobic digestion for manure management in dairy farms in Mexico: a life cycle perspective.

PubMed

Rivas-García, Pasiano; Botello-Álvarez, José E; Abel Seabra, Joaquim E; da Silva Walter, Arnaldo C; Estrada-Baltazar, Alejandro

2015-01-01

The environmental profile of milk production in Mexico was analysed for three manure management scenarios: fertilization (F), anaerobic digestion (AD) and enhanced anaerobic digestion (EAD). The study used the life cycle assessment (LCA) technique, considering a 'cradle-to-gate' approach. The assessment model was constructed using SimaPro LCA software, and the life cycle impact assessment was performed according to the ReCiPe method. Dairy farms with AD and EAD scenarios were found to exhibit, respectively, 12% and 27% less greenhouse gas emissions, 58% and 31% less terrestrial acidification, and 3% and 18% less freshwater eutrophication than the F scenario. A different trend was observed in the damage to resource availability indicator, as the F scenario presented 6% and 22% less damage than the EAD and AD scenarios, respectively. The magnitude of environmental damage from milk production in the three dairy manure management scenarios, using a general single score indicator, was 0.118, 0.107 and 0.081 Pt/L of milk for the F, AD and EAD scenarios, respectively. These results indicate that manure management systems with anaerobic digestion can improve the environmental profile of each litre of milk produced.

So little source, so much sink: requirements for afterdepolarizations to propagate in tissue.

PubMed

Xie, Yuanfang; Sato, Daisuke; Garfinkel, Alan; Qu, Zhilin; Weiss, James N

2010-09-08

How early (EADs) and delayed afterdepolarizations (DADs) overcome electrotonic source-sink mismatches in tissue to trigger premature ventricular complexes remains incompletely understood. To study this question, we used a rabbit ventricular action potential model to simulate tissues in which a central area of contiguous myocytes susceptible to EADs or DADs was surrounded by unsusceptible tissue. In 1D tissue with normal longitudinal conduction velocity (0.55 m/s), the numbers of contiguous susceptible myocytes required for an EAD and a barely suprathreshold DAD to trigger a propagating action potential were 70 and 80, respectively. In 2D tissue, these numbers increased to 6940 and 7854, and in 3D tissue to 696,910 and 817,280. These numbers were significantly decreased by reduced gap junction conductance, simulated fibrosis, reduced repolarization reserve and heart failure electrical remodeling. In conclusion, the source-sink mismatch in well-coupled cardiac tissue powerfully protects the heart from arrhythmias due to sporadic afterdepolarizations. Structural and electrophysiological remodeling decrease these numbers significantly but still require synchronization mechanisms for EADs and DADs to overcome the robust protective effects of source-sink mismatch. Copyright 2010 Biophysical Society. Published by Elsevier Inc. All rights reserved.

DFT study on the adsorption behavior and electronic response of AlN nanotube and nanocage toward toxic halothane gas

NASA Astrophysics Data System (ADS)

Mohammadi, R.; Hosseinian, A.; Khosroshahi, E. Saedi; Edjlali, L.; Vessally, E.

2018-04-01

We have investigated the adsorption of a halothane molecule on the AlN nanotube, and nanocage using density functional theory calculations. We predicted that the halothane molecule tends to be physically adsorbed on the surface of AlN nanotube with adsorption energy (Ead) of -4.2 kcal/mol. The electronic properties of AlN nanotube are not affected by the halothane, and it is not a sensor. But the AlN nanocage is more reactive than the AlN nanotube because of its higher curvature. The halothane tends to be adsorbed on a hexagonal ring, an Alsbnd N bond, and a tetragonal ring of the AlN nanocage. The adsorption ability order is as follows: tetragonal ring (Ead = -14.7 kcal/mol) > Alsbnd N bond (Ead = -12.3 kcal/mol) > hexagonal ring (Ead = -10.1 kcal/mol). When a halothane molecule is adsorbed on the AlN nanocage, its electrical conductivity is increased, demonstrating that it can yield an electronic signal at the presence of this molecule, and can be employed in chemical sensors. The AlN nanocage benefits from a short recovery time of about 58 ms at room temperature.

Effect of myocyte-fibroblast coupling on the onset of pathological dynamics in a model of ventricular tissue

NASA Astrophysics Data System (ADS)

Sridhar, S.; Vandersickel, Nele; Panfilov, Alexander V.

2017-01-01

Managing lethal cardiac arrhythmias is one of the biggest challenges in modern cardiology, and hence it is very important to understand the factors underlying such arrhythmias. While early afterdepolarizations (EAD) of cardiac cells is known to be one such arrhythmogenic factor, the mechanisms underlying the emergence of tissue level arrhythmias from cellular level EADs is not fully understood. Another known arrhythmogenic condition is fibrosis of cardiac tissue that occurs both due to aging and in many types of heart diseases. In this paper we describe the results of a systematic in-silico study, using the TNNP model of human cardiac cells and MacCannell model for (myo)fibroblasts, on the possible effects of diffuse fibrosis on arrhythmias occurring via EADs. We find that depending on the resting potential of fibroblasts (VFR), M-F coupling can either increase or decrease the region of parameters showing EADs. Fibrosis increases the probability of occurrence of arrhythmias after a single focal stimulation and this effect increases with the strength of the M-F coupling. While in our simulations, arrhythmias occur due to fibrosis induced ectopic activity, we do not observe any specific fibrotic pattern that promotes the occurrence of these ectopic sources.

Extraglottic airway devices: technology update.

PubMed

Sharma, Bimla; Sahai, Chand; Sood, Jayashree

2017-01-01

Extraglottic airway devices (EADs) have revolutionized the field of airway management. The invention of the laryngeal mask airway was a game changer, and since then, there have been several innovations to improve the EADs in design, functionality, safety and construction material. These have ranged from changes in the shape of the mask, number of cuffs and material used, like rubber, polyvinylchloride and latex. Phthalates, which were added to the construction material in order to increase device flexibility, were later omitted when this chemical was found to have serious adverse reproductive outcomes. The various designs brought out by numerous companies manufacturing EADs resulted in the addition of several devices to the airway market. These airway devices were put to use, many of them with inadequate or no evidence base regarding their efficacy and safety. To reduce the possibility of compromising the safety of the patient, the Difficult Airway Society (DAS) formed the Airway Device Evaluation Project Team (ADEPT) to strengthen the evidence base for airway equipment and vet the new extraglottic devices. A preuse careful analysis of the design and structure may help in better understanding of the functionality of a particular device. In the meantime, the search for the ideal EAD continues.

Digitized Archival Primary Sources in STEM: A Selected Webliography

ERIC Educational Resources Information Center

Jankowski, Amy

2017-01-01

Accessibility and findability of digitized archival resources can be a challenge, particularly for students or researchers not familiar with archival formats and digital interfaces, which adhere to different descriptive standards than more widely familiar library resources. Numerous aggregate archival collection databases exist, which provide a…

Impairment in proverb interpretation as an executive function deficit in patients with amnestic mild cognitive impairment and early Alzheimer's disease.

PubMed

Leyhe, Thomas; Saur, Ralf; Eschweiler, Gerhard W; Milian, Monika

2011-01-01

Proverb interpretation is assumed to reflect executive functions. We hypothesized that proverb interpretation is impaired in patients with amnestic mild cognitive impairment (aMCI) diagnosed as single-domain impairment by common neuropsychological testing. We compared performance in a proverb interpretation test in single-domain aMCI patients and patients with early Alzheimer's disease (EAD). The groups with aMCI and EAD performed significantly worse than healthy controls. Both patient groups gave concrete answers with a similar frequency. However, patients with EAD tended to give senseless answers more frequently. Our data suggest that in patients diagnosed as single-domain aMCI, deterioration of executive functions is detectable with subtle and appropriate neuropsychological testing. Implementation of these procedures may improve the early prediction of AD.

Cassini/Huygens Program Archive Plan for Science Data

NASA Technical Reports Server (NTRS)

Conners, D.

2000-01-01

The purpose of this document is to describe the Cassini/Huygens science data archive system which includes policy, roles and responsibilities, description of science and supplementary data products or data sets, metadata, documentation, software, and archive schedule and methods for archive transfer to the NASA Planetary Data System (PDS).

Fast steering mirror for laser communication

NASA Astrophysics Data System (ADS)

Langenbach, Harald; Schmid, Manfred

2005-07-01

Future multimedia satellites require communication at large bandwidth which can be achieved by means of optical communication links. TESAT Spacecom is currently developing a Laser Communication Terminal (LCT) for such applications under DLR contract. EADS Astrium is developing and building the mechanisms for Pointing, Acquisition and Tracking (PAT) of the laser beam between two Laser Communication Terminals. Based on this development work the development of mechanism H/W to be flown on TerraSar X is currently under way. After a short description of the general arrangement of the Mechanisms inside the LCT, the paper describes the design of the fast steering mirrors (FSM) reflecting the critical requirements and the solutions how to achieve them.

Using and Distributing Spaceflight Data: The Johnson Space Center Life Sciences Data Archive

NASA Technical Reports Server (NTRS)

Cardenas, J. A.; Buckey, J. C.; Turner, J. N.; White, T. S.; Havelka,J. A.

1995-01-01

Life sciences data collected before, during and after spaceflight are valuable and often irreplaceable. The Johnson Space Center Life is hard to find, and much of the data (e.g. Sciences Data Archive has been designed to provide researchers, engineers, managers and educators interactive access to information about and data from human spaceflight experiments. The archive system consists of a Data Acquisition System, Database Management System, CD-ROM Mastering System and Catalog Information System (CIS). The catalog information system is the heart of the archive. The CIS provides detailed experiment descriptions (both written and as QuickTime movies), hardware descriptions, hardware images, documents, and data. An initial evaluation of the archive at a scientific meeting showed that 88% of those who evaluated the catalog want to use the system when completed. The majority of the evaluators found the archive flexible, satisfying and easy to use. We conclude that the data archive effectively provides key life sciences data to interested users.

Increasing Access to Archival Records in Library Online Public Access Catalogs.

ERIC Educational Resources Information Center

Gilmore, Matthew B.

1988-01-01

Looks at the use of online public access catalogs, the utility of subject and call-number searching, and possible archival applications. The Wallace Archives at the Claremont Colleges is used as an example of the availability of bibliographic descriptions of multiformat archival materials through the library catalog. Sample records and searches…

Clay Tablets to Micro Chips: The Evolution of Archival Practice into the Twenty-First Century.

ERIC Educational Resources Information Center

Hannestad, Stephen E.

1991-01-01

Describes archival concepts and theories and their evolution in recent times. Basic archival functions--appraisal, arrangement, description, reference, preservation, and publication--are introduced. Early applications of automation to archives (including SPINDEX, NARS-5, NARS-A-1, MARC AMC, presNET, CTRACK, PHOTO, and DIARY) and automation trends…

Equivalent air depth: fact or fiction.

PubMed

Berghage, T E; McCraken, T M

1979-12-01

In mixed-gas diving theory, the equivalent air depth (EAD) concept suggests that oxygen does not contribute to the total tissue gas tension and can therefore be disregarded in calculations of the decompression process. The validity of this assumption has been experimentally tested by exposing 365 rats to various partial pressures of oxygen for various lengths of time. If the EAD assumption is correct, under a constant exposure pressure each incremental change in the oxygen partial pressure would produce a corresponding incremental change in pressure reduction tolerance. Results of this study suggest that the EAD concept does not adequately describe the decompression advantages obtained from breathing elevated oxygen partial pressures. The authors suggest that the effects of breathing oxygen vary in a nonlinear fashion across the range from anoxia to oxygen toxicity, and that a simple inert gas replacement concept is no longer tenable.

Impairment in Proverb Interpretation as an Executive Function Deficit in Patients with Amnestic Mild Cognitive Impairment and Early Alzheimer's Disease

PubMed Central

Leyhe, Thomas; Saur, Ralf; Eschweiler, Gerhard W.; Milian, Monika

2011-01-01

Background/Aims Proverb interpretation is assumed to reflect executive functions. We hypothesized that proverb interpretation is impaired in patients with amnestic mild cognitive impairment (aMCI) diagnosed as single-domain impairment by common neuropsychological testing. Methods We compared performance in a proverb interpretation test in single-domain aMCI patients and patients with early Alzheimer's disease (EAD). Results The groups with aMCI and EAD performed significantly worse than healthy controls. Both patient groups gave concrete answers with a similar frequency. However, patients with EAD tended to give senseless answers more frequently. Conclusions Our data suggest that in patients diagnosed as single-domain aMCI, deterioration of executive functions is detectable with subtle and appropriate neuropsychological testing. Implementation of these procedures may improve the early prediction of AD. PMID:22163233

Optimization of Supercomputer Use on EADS II System

NASA Technical Reports Server (NTRS)

Ahmed, Ardsher

1998-01-01

The main objective of this research was to optimize supercomputer use to achieve better throughput and utilization of supercomputers and to help facilitate the movement of non-supercomputing (inappropriate for supercomputer) codes to mid-range systems for better use of Government resources at Marshall Space Flight Center (MSFC). This work involved the survey of architectures available on EADS II and monitoring customer (user) applications running on a CRAY T90 system.

Quarrelsome Committees in U.S. Defense Acquisition: The KC-X Case

DTIC Science & Technology

2014-04-30

close to its original specifications in the RfP published on February 24, 2010. NG-EADS supporters were decidedly negative. Sen. Sessions ( R -AL...party. Thus, for example, the Boeing congressional delegation included Rep. Todd Tiahrt ( R -KS), along with the largely Democratic Washington State...delegation. The congressional EADS supporters included Sen. Jeff Sessions ( R -AL). And political figures stepped up to claim a major role in changing

[Subjective cognitive impairment and Alzheimer's disease: a two year follow up of 51 subjects during two years].

PubMed

Sambuchi, Nathalie; Muraccioli, Isabelle; Alescio-Lautier, Béatrice; Paban, Véronique; Sambuc, Roland; Jouve, Élisabeth; Geda, Yonas Endale; Petersen, Ronald Karl; Michel, Bernard François

2015-12-01

Subjective cognitive impairment (SCI) is defined by a state of subjective complaint, without objective cognitive deterioration. Amnestic mild cognitive impairment (A-MCI), which characterizes a syndrome between normal cognitive aging and early Alzheimer's disease (E-AD), is preceded by A-MCI from many years. SCI expresses a metacognitive impairment. A cohort of 51 subjects [7 normal controls (NC), 28 SCI, 12 A-MCI and 5 E-AD] was followed up during 24 months, with a neuropsychological evaluation each 6 months during 1 year (V1, V2, V3), then 1 year later (V4). Among the 28 SCI, 6 converted to A-MCI at V4 (21.42%), 1 to A-MCI-A at V3, then to E-AD at V4. These results suggest a continuum from SCI to A-MCI, and E-AD. Progressive SCI differed from non-progressive SCI on verbal episodic memory and executive functions tests at the initial examination. MRI showed anterior cingular atrophy in all SCI patients but hippocampal atrophy was only observed in 20 patients. Our results suggest that metacognition impairment is the expression of a dysfunction in the anterior pre-frontal cortex, in correlation with a syndrome of hyper-attention.

Quantitative computed tomography and aerosol morphometry in COPD and alpha1-antitrypsin deficiency.

PubMed

Shaker, S B; Maltbaek, N; Brand, P; Haeussermann, S; Dirksen, A

2005-01-01

Relative area of emphysema below -910 Hounsfield units (RA-910) and 15th percentile density (PD15) are quantitative computed tomography (CT) parameters used in the diagnosis of emphysema. New concepts for noninvasive diagnosis of emphysema are aerosol-derived airway morphometry, which measures effective airspace dimensions (EAD) and aerosol bolus dispersion (ABD). Quantitative CT, ABD and EAD were compared in 20 smokers with chronic obstructive pulmonary disease (COPD) and 22 patients with alpha1-antitrypsin deficiency (AAD) with a similar degree of airway obstruction and reduced diffusion capacity. In both groups, there was a significant correlation between RA-910 and PD15 and pulmonary function tests (PFTs). A significant correlation was also found between EAD, RA-910 and PD15 in the study population as a whole. Upon separation into two groups, the significance disappeared for the smokers with COPD and strengthened for those with AAD, where EAD correlated significantly with RA-910 and PD15. ABD was similar in the two groups and did not correlate with PFT and quantitative CT in either group. In conclusion, based on quantitative computed tomography and aerosol-derived airway morphometry, emphysema was significantly more severe in patients with alpha1-antitrypsin deficiency compared with patients with usual emphysema, despite similar measures of pulmonary function tests.

How Twenty-Five People Shook the Archival World: The Case of Descriptive Standards

ERIC Educational Resources Information Center

Davis, Susan E.

2006-01-01

This study explores the development of the archival profession during the 1980s, a period that experienced rapid change and the adoption of the first descriptive standards. The research focuses on the leadership roles played by individuals acting independently and on behalf of their employing institutions and professional associations in the…

Archive data base and handling system for the Orbiter flying qualities experiment program

NASA Technical Reports Server (NTRS)

Myers, T. T.; Dimarco, R.; Magdaleno, R. E.; Aponso, B. L.

1986-01-01

The OFQ archives data base and handling system assembled as part of the Orbiter Flying Qualities (OFQ) research of the Orbiter Experiments Program (EOX) are described. The purpose of the OFQ archives is to preserve and document shuttle flight data relevant to vehicle dynamics, flight control, and flying qualities in a form that permits maximum use for qualified users. In their complete form, the OFQ archives contain descriptive text (general information about the flight, signal descriptions and units) as well as numerical time history data. Since the shuttle program is so complex, the official data base contains thousands of signals and very complex entries are required to obtain data. The OFQ archives are intended to provide flight phase oriented data subsets with relevant signals which are easily identified for flying qualities research.

Temperature and strain characterization of long period gratings in air guiding fiber

NASA Astrophysics Data System (ADS)

Iadicicco, Agostino; Cutolo, Antonello; Cusano, Andrea; Campopiano, Stefania

2013-05-01

This paper reports on the fabrication of Long Period Gratings (LPGs) in hollow-core air-silica photonic bandgap fibers by using pressure assisted Electrode Arc Discharge (EAD) technique. In particular, the fabrication procedure relies on the combined use of EAD step, to locally heat the HC fiber, and of a static pressure (slightly higher than the external one) inside the fiber holes, to modify the holes. This procedure permits to preserve the holey structure of the host fiber avoiding any hole collapsing and it enables a local effective refractive index change due to the size and shape modifications of core and cladding holes. Periodically repeated EAD treatments permit the fabrication of LPGs based devices in hollow core optical fibers enabling new functionalities hitherto not possible. Here, the experimental fabrication of LPG prototypes with different periods and lengths are discussed. And, the HC-LPGs sensitivity to environmental parameters such as strain and temperature are investigated.

An Invitation to the ALA Archives.

ERIC Educational Resources Information Center

Beckel, Deborah; Brichford, Maynard

1984-01-01

Description of materials found in American Library Association Archives located at University of Illinois highlights 1905 letter defending Melvil Dewey, the 1900 Saguenay River Trip, children's librarians, library education, 1926 visit to President Coolidge by foreign librarians, and the American Library in Mexico. Notes on using the archives are…

Implications of an Economic Recession on European Defense

DTIC Science & Technology

2011-03-10

in the best interest of the U.S. Europe is on the verge of no longer being a credible military partner of the U.S. A new construct that equitably... construction of warships symbolize protectionism at its best. States and defense firms are forced to manage competition on the global market in order...visible firms are EADS and MBDA. EADS was created through the merger of France‟s Aerospatiale Matra, Spain‟s Construcciones Aeronauticas, and Germany

The GNC Measurement System for the Automated Transfer Vehicle

NASA Astrophysics Data System (ADS)

Roux, Y.; da Cunha, P.

The Automated Transfer Vehicle (ATV) is a European Space Agency (ESA) funded spacecraft developed by EADS Space Transportation as prime contractor for the space segment together with major European industrial partners, in the frame of the International Space Station (ISS). Its mission objective is threefold : to supply the station with fret and propellant, to reboost ISS to a higher orbit and to dispose of waste from the station. The ATV first flight, called Jules Verne and planned on 2005, will be the first European Vehicle to perform an orbital rendezvous. The GNC Measurement System (GMS) is the ATV on board function in charge of the measurement data collection and preconditioning for the navigation, guidance and control (GNC) algorithms. The GMS is made up of hardware which are the navigation sensors (with a certain level of hardware redundancy for each of them), and of an on-board software that manages, monitors and performs consistency checks to detect and isolate potential sensor failures. The GMS relies on six kinds of navigation sensors, used during various phases of the mission : the gyrometers assembly (GYRA), the accelerometers assembly (ACCA), the star trackers (STR), the GPS receivers, the telegoniometers (TGM) and the videometers (VDM), the last two being used for the final rendezvous phase. The GMS function is developed by EADS Space Transportation together with other industrial partners: EADS Astrium, EADS Sodern, Laben and Dasa Jena Optronik.

Detecting navigational deficits in cognitive aging and Alzheimer disease using virtual reality

PubMed Central

Cushman, Laura A.; Stein, Karen; Duffy, Charles J.

2008-01-01

Background: Older adults get lost, in many cases because of recognized or incipient Alzheimer disease (AD). In either case, getting lost can be a threat to individual and public safety, as well as to personal autonomy and quality of life. Here we compare our previously described real-world navigation test with a virtual reality (VR) version simulating the same navigational environment. Methods: Quantifying real-world navigational performance is difficult and time-consuming. VR testing is a promising alternative, but it has not been compared with closely corresponding real-world testing in aging and AD. We have studied navigation using both real-world and virtual environments in the same subjects: young normal controls (YNCs, n = 35), older normal controls (ONCs, n = 26), patients with mild cognitive impairment (MCI, n = 12), and patients with early AD (EAD, n = 14). Results: We found close correlations between real-world and virtual navigational deficits that increased across groups from YNC to ONC, to MCI, and to EAD. Analyses of subtest performance showed similar profiles of impairment in real-world and virtual testing in all four subject groups. The ONC, MCI, and EAD subjects all showed greatest difficulty in self-orientation and scene localization tests. MCI and EAD patients also showed impaired verbal recall about both test environments. Conclusions: Virtual environment testing provides a valid assessment of navigational skills. Aging and Alzheimer disease (AD) share the same patterns of difficulty in associating visual scenes and locations, which is complicated in AD by the accompanying loss of verbally mediated navigational capacities. We conclude that virtual navigation testing reveals deficits in aging and AD that are associated with potentially grave risks to our patients and the community. GLOSSARY AD = Alzheimer disease; EAD = early Alzheimer disease; MCI = mild cognitive impairment; MMSE = Mini-Mental State Examination; ONC = older normal control; std. wt. = standardized weight; THSD = Tukey honestly significant difference; VR = virtual reality; YNC = young normal control. PMID:18794491

Confirmatory/release survey of the property at 71 Pearce Avenue (Former EAD Building) in Tonawanda, New York

DOE Office of Scientific and Technical Information (OSTI.GOV)

Salame-Alfie, A.; Alibozek, R.

1995-12-31

EAD Metallurgical, Inc., operated a facility in Tonawanda, New York, in which it utilized Americium 241 (Am-241) for the production of foil sources for use in smoke detectors. EAD was in operation between 1977 and 1983. By 1983, the company started losing money, and decided to relocate to Mexico. Before closing down its Tonawanda operation, however, it was required by the New York State Department of Labor (DOL) to decontaminate its facility to limits specified by DOL. No records of discharges to the sewer system were kept during this decontamination effort. Unsuccessful decontamination efforts by several EAD employees and contractorsmore » left the building contaminated, in particular the concrete floors and walls. To determine the scope of work for the decontamination project, staff from the New York State Departments of Health (DOH) and Environmental Conservation (DEC) conducted a Characterization Survey of the facility in 1993. This survey identified contamination levels of Am-241 in excess of release limits throughout the building, in the soil outside the facility, in pipes for sewage and interior drainage, and in an 8 x 8 x 11 foot sump pit in the building. DOH issued a request for proposals in early 1994 for the decontamination and subsequent decommissioning of the former EAD building, and NES/IES Inc. (NES) was awarded the contract to perform the remediation. DOH`s assignment was to provide an on-site presence to insure the completion of all agreed upon tasks, according to the terms of the contract and work plans submitted by NES. Additionally, the DOH staff acted as a liaison between NES, DOH, DEC and DOL central offices to review, comment and approve all changes or modifications to NES`s approach to the decontamination efforts. The assigned staff was also responsible for conducting confirmatory sampling and surveys of all areas deemed releasable to DOL and DEC criteria by NES.« less

Transient Outward K+ Current (Ito) Underlies the Right Ventricular Initiation of Polymorphic Ventricular Tachycardia in a Transgenic Rabbit Model of Long-QT Syndrome Type 1.

PubMed

Choi, Bum-Rak; Li, Weiyan; Terentyev, Dmitry; Kabakov, Anatoli Y; Zhong, Mingwang; Rees, Colin M; Terentyeva, Radmila; Kim, Tae Yun; Qu, Zhilin; Peng, Xuwen; Karma, Alain; Koren, Gideon

2018-06-01

Sudden death in long-QT syndrome type 1 (LQT1), an inherited disease caused by loss-of-function mutations in KCNQ1, is triggered by early afterdepolarizations (EADs) that initiate polymorphic ventricular tachycardia (pVT). We investigated ionic mechanisms that underlie pVT in LQT1 using a transgenic rabbit model of LQT1. Optical mapping, cellular patch clamping, and computer modeling were used to elucidate the mechanisms of EADs in transgenic LQT1 rabbits. The results showed that shorter action potential duration in the right ventricle (RV) was associated with focal activity during pVT initiation. RV cardiomyocytes demonstrated higher incidence of EADs under 50 nmol/L isoproterenol. Voltage-clamp studies revealed that the transient outward potassium current (I to ) magnitude was 28% greater in RV associated with KChiP2 but with no differences in terms of calcium-cycling kinetics and other sarcolemmal currents. Perfusing with the I to blocker 4-aminopyridine changed the initial focal sites of pVT from the RV to the left ventricle, corroborating the role of I to in pVT initiation. Computer modeling showed that EADs occur preferentially in the RV because of the larger conductance of the slow-inactivating component of I to , which repolarizes the membrane potential sufficiently rapidly to allow reactivation of I Ca,L before I Kr has had sufficient time to activate. I to heterogeneity creates both triggers and an arrhythmogenic substrate in LQT1. In the absence of I Ks , I to interactions with I Ca,L and I Kr promote EADs in the RV while prolonging action potential duration in the left ventricle. This heterogeneity of action potential enhances dispersion of refractoriness and facilitates conduction blocks that initiate pVTs. © 2018 American Heart Association, Inc.

Identification and field evaluation of fermentation volatiles from wine and vinegar that mediate attraction of spotted wing Drosophila, Drosophila suzukii.

PubMed

Cha, Dong H; Adams, Todd; Rogg, Helmuth; Landolt, Peter J

2012-11-01

Previous studies suggest that olfactory cues from damaged and fermented fruits play important roles in resource recognition of polyphagous spotted wing Drosophila flies (SWD), Drosophila suzukii (Matsumura) (Diptera: Drosophilidae). They are attracted to fermented sweet materials, such as decomposing fruits but also wines and vinegars, and to ubiquitous fermentation volatiles, such as acetic acid and ethanol. Gas chromatography coupled with electroantennographic detection (GC-EAD), gas chromatography-mass spectrometry (GC-MS), two-choice laboratory bioassays, and field trapping experiments were used to identify volatile compounds from wine and vinegar that are involved in SWD attraction. In addition to acetic acid and ethanol, consistent EAD responses were obtained for 13 volatile wine compounds and seven volatile vinegar compounds, with all of the vinegar EAD-active compounds also present in wine. In a field trapping experiment, the 9-component vinegar blend and 15-component wine blend were similarly attractive when compared to an acetic acid plus ethanol mixture, but were not as attractive as the wine plus vinegar mixture. In two-choice laboratory bioassays, 7 EAD-active compounds (ethyl acetate, ethyl butyrate, ethyl lactate, 1-hexanol, isoamyl acetate, 2-methylbutyl acetate, and ethyl sorbate), when added singly to the mixture at the same concentrations tested in the field, decreased the attraction of SWD to the mixture of acetic acid and ethanol. The blends composed of the remaining EAD-active chemicals, an 8-component wine blend [acetic acid + ethanol + acetoin + grape butyrate + methionol + isoamyl lactate + 2-phenylethanol + diethyl succinate] and a 5-component vinegar blend [acetic acid + ethanol + acetoin + grape butyrate + 2-phenylethanol] were more attractive than the acetic acid plus ethanol mixture, and as attractive as the wine plus vinegar mixture in both laboratory assays and the field trapping experiment. These results indicate that these volatiles in wine and vinegar are crucial for SWD attraction to fermented materials on which they feed as adults.

A model of cardiac ryanodine receptor gating predicts experimental Ca2+-dynamics and Ca2+-triggered arrhythmia in the long QT syndrome

NASA Astrophysics Data System (ADS)

Wilson, Dan; Ermentrout, Bard; Němec, Jan; Salama, Guy

2017-09-01

Abnormal Ca2+ handling is well-established as the trigger of cardiac arrhythmia in catecholaminergic polymorphic ventricular tachycardia and digoxin toxicity, but its role remains controversial in Torsade de Pointes (TdP), the arrhythmia associated with the long QT syndrome (LQTS). Recent experimental results show that early afterdepolarizations (EADs) that initiate TdP are caused by spontaneous (non-voltage-triggered) Ca2+ release from Ca2+-overloaded sarcoplasmic reticulum (SR) rather than the activation of the L-type Ca2+-channel window current. In bradycardia and long QT type 2 (LQT2), a second, non-voltage triggered cytosolic Ca2+ elevation increases gradually in amplitude, occurs before overt voltage instability, and then precedes the rise of EADs. Here, we used a modified Shannon-Puglisi-Bers model of rabbit ventricular myocytes to reproduce experimental Ca2+ dynamics in bradycardia and LQT2. Abnormal systolic Ca2+-oscillations and EADs caused by SR Ca2+-release are reproduced in a modified 0-dimensional model, where 3 gates in series control the ryanodine receptor (RyR2) conductance. Two gates control RyR2 activation and inactivation and sense cytosolic Ca2+ while a third gate senses luminal junctional SR Ca2+. The model predicts EADs in bradycardia and low extracellular [K+] and cessation of SR Ca2+-release terminate salvos of EADs. Ca2+-waves, systolic cell-synchronous Ca2+-release, and multifocal diastolic Ca2+ release seen in subcellular Ca2+-mapping experiments are observed in the 2-dimensional version of the model. These results support the role of SR Ca2+-overload, abnormal SR Ca2+-release, and the subsequent activation of the electrogenic Na+/Ca2+-exchanger as the mechanism of TdP. The model offers new insights into the genesis of cardiac arrhythmia and new therapeutic strategies.

French Interim MALE UAV Program

DTIC Science & Technology

2003-09-02

MINISTÈRE DE LA DÉFENSE June, 13th 2002 Lcl Monsterleet FAF Staff J. Caron EADS S&DE-ISR FRENCH INTERIM MALE UAV PROGRAM 4 INDUSTRIAL STATUS Report...2003 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE French Interim Male UAV Program 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c...PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) EADS

A Missing PD-L1/PD-1 Coinhibition Regulates Diabetes Induction by Preproinsulin-Specific CD8 T-Cells in an Epitope-Specific Manner

PubMed Central

Schuster, Cornelia; Brosi, Helen; Stifter, Katja; Boehm, Bernhard O.; Schirmbeck, Reinhold

2013-01-01

Coinhibitory PD-1/PD-L1 (B7-H1) interactions provide critical signals for the regulation of autoreactive T-cell responses. We established mouse models, expressing the costimulator molecule B7.1 (CD80) on pancreatic beta cells (RIP-B7.1 tg mice) or are deficient in coinhibitory PD-L1 or PD-1 molecules (PD-L1−/− and PD-1−/− mice), to study induction of preproinsulin (ppins)-specific CD8 T-cell responses and experimental autoimmune diabetes (EAD) by DNA-based immunization. RIP-B7.1 tg mice allowed us to identify two CD8 T-cell specificities: pCI/ppins DNA exclusively induced Kb/A12–21-specific CD8 T-cells and EAD, whereas pCI/ppinsΔA12–21 DNA (encoding ppins without the COOH-terminal A12–21 epitope) elicited Kb/B22–29-specific CD8 T-cells and EAD. Specific expression/processing of mutant ppinsΔA12–21 (but not ppins) in non-beta cells, targeted by intramuscular DNA-injection, thus facilitated induction of Kb/B22–29-specific CD8 T-cells. The A12–21 epitope binds Kb molecules with a very low avidity as compared with B22–29. Interestingly, immunization of coinhibition-deficient PD-L1−/− or PD-1−/− mice with pCI/ppins induced Kb/A12–21-monospecific CD8 T-cells and EAD but injections with pCI/ppinsΔA12–21 did neither recruit Kb/B22–29-specific CD8 T-cells into the pancreatic target tissue nor induce EAD. PpinsΔA12–21/(Kb/B22–29)-mediated EAD was efficiently restored in RIP-B7.1+/PD-L1−/− mice, differing from PD-L1−/− mice only in the tg B7.1 expression in beta cells. Alternatively, an ongoing beta cell destruction and tissue inflammation, initiated by ppins/(Kb/A12–21)-specific CD8 T-cells in pCI/ppins+pCI/ppinsΔA12–21 co-immunized PD-L1−/− mice, facilitated the expansion of ppinsΔA12–21/(Kb/B22–29)-specific CD8 T-cells. CD8 T-cells specific for the high-affinity Kb/B22–29- (but not the low-affinity Kb/A12–21)-epitope thus require stimulatory ´help from beta cells or inflamed islets to expand in PD-L1-deficient mice. The new PD-1/PD-L1 diabetes models may be valuable tools to study under well controlled experimental conditions distinct hierarchies of autoreactive CD8 T-cell responses, which trigger the initial steps of beta cell destruction or emerge during the pathogenic progression of EAD. PMID:23977133

Publications - GMC 407 | Alaska Division of Geological & Geophysical

Science.gov Websites

locations, and archive inventory for 32 near-shore marine sediment Vibracore samples, West Dock Causeway , Drilling procedures, sample descriptions, boring logs, borehole locations, and archive inventory for 32

Acute effect of ambient air pollution on heart failure in Guangzhou, China.

PubMed

Yang, Changyuan; Chen, Ailan; Chen, Renjie; Qi, Yongqing; Ye, Jianjun; Li, Shuangming; Li, Wanglin; Liang, Zijing; Liang, Qing; Guo, Duanqiang; Kan, Haidong; Chen, Xinyu

2014-12-15

Heart failure (HF) is a global public health problem of increasing importance. The association between acute exposure to air pollution and HF has been well established in developed countries, but little evidence was available in developing countries where air pollution levels were much higher. We conducted a time-series study to investigate the short-term association between air pollution and overall emergency ambulance dispatches (EAD) due to HF in Guangzhou, China. Daily data of EAD due to HF from 1 January 2008 to 31 December 2012 were obtained from Guangzhou Emergency Center. We applied the over-dispersed Poisson generalized addictive model to analyze the associations after controlling for the seasonality, day of the week and weather conditions. We identified a total of 3375 EAD for HF. A 10-μg/m(3) increase in the present-day concentrations of particulate matter with an aerodynamic diameter of less than 10 μm, sulfur dioxide and nitrogen dioxide corresponded to increases of 3.54% [95% confidence interval (CI): 1.35%, 5.74%], 5.29% (95% CI: 2.28%, 8.30%) and 4.34% (95% CI: 1.71%, 6.97%) in daily EAD for HF, respectively. The effects of air pollution on acute HF were restricted on the concurrent day and in the cool seasons. Our results provided the first population-based evidence in Mainland China that outdoor air pollution could trigger the exacerbation of HF. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

User interface development and metadata considerations for the Atmospheric Radiation Measurement (ARM) archive

NASA Technical Reports Server (NTRS)

Singley, P. T.; Bell, J. D.; Daugherty, P. F.; Hubbs, C. A.; Tuggle, J. G.

1993-01-01

This paper will discuss user interface development and the structure and use of metadata for the Atmospheric Radiation Measurement (ARM) Archive. The ARM Archive, located at Oak Ridge National Laboratory (ORNL) in Oak Ridge, Tennessee, is the data repository for the U.S. Department of Energy's (DOE's) ARM Project. After a short description of the ARM Project and the ARM Archive's role, we will consider the philosophy and goals, constraints, and prototype implementation of the user interface for the archive. We will also describe the metadata that are stored at the archive and support the user interface.

EAC and the Development of National and European Gateways to Archives

ERIC Educational Resources Information Center

Ottosson, Per-Gunnar

2005-01-01

In the development of gateways to archives there are two different approaches, one focusing on the descriptions of the material and the other on the creators. Search and retrieval with precision and quality require controlled access points and name authority control. National registries of private archives have a long tradition in implementing the…

ESA'S Biomass Mission System And Payload Overview

NASA Astrophysics Data System (ADS)

Arcioni, M.; Bensi, P.; Fois, F.; Gabriele, A.; Heliere, F.; Lin, C. C.; Massotti, L.; Scipal, K.

2013-12-01

Earth Explorers are the backbone of the science and research element of ESA's Living Planet Programme, providing an important contribution to the understanding of the Earth system. Following the User Consultation Meeting held in Graz, Austria on 5-6 March 2013, the Earth Science Advisory Committee (ESAC) has recommended implementing Biomass as the 7th Earth Explorer Mission within the frame of the ESA Earth Observation Envelope Programme. This paper will give an overview of the satellite system and its payload. The system technical description presented here is based on the results of the work performed during parallel Phase A system studies by two industrial consortia led by EADS Astrium Ltd. and Thales Alenia Space Italy. Two implementation concepts (respectively A and B) are described and provide viable options capable of meeting the mission requirements.

ITS data archiving : five-year program description

DOT National Transportation Integrated Search

2000-03-01

The purpose of this document is to explain the need for and elements of a Federal program : addressing the archiving and multi-agency use of data generated from Intelligent : Transportation Systems (ITS) applications. The development of this program ...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shoopman, J. D.

This report documents Livermore Computing (LC) activities in support of ASC L2 milestone 5589: Modernization and Expansion of LLNL Archive Disk Cache, due March 31, 2016. The full text of the milestone is included in Attachment 1. The description of the milestone is: Description: Configuration of archival disk cache systems will be modernized to reduce fragmentation, and new, higher capacity disk subsystems will be deployed. This will enhance archival disk cache capability for ASC archive users, enabling files written to the archives to remain resident on disk for many (6–12) months, regardless of file size. The milestone was completed inmore » three phases. On August 26, 2015 subsystems with 6PB of disk cache were deployed for production use in LLNL’s unclassified HPSS environment. Following that, on September 23, 2015 subsystems with 9 PB of disk cache were deployed for production use in LLNL’s classified HPSS environment. On January 31, 2016, the milestone was fully satisfied when the legacy Data Direct Networks (DDN) archive disk cache subsystems were fully retired from production use in both LLNL’s unclassified and classified HPSS environments, and only the newly deployed systems were in use.« less

ITS data archiving : five-year program description

DOT National Transportation Integrated Search

2000-05-01

The purpose of this document is to explain the need for and elements of a Federal program addressing the archiving and multi-agency use of data generated from Intelligent Transportation Systems (ITS) applications. The development of this program buil...

Anti-Collision Function Design and Performances of the CNES Formation Flying Experiment on the PRISMA Mission

NASA Technical Reports Server (NTRS)

Cayeux, P.; Raballand, F.; Borde, J.; Berges, J.-C.; Meyssignac, B.

2007-01-01

Within the framework of a partnership agreement, EADS ASTRIUM has worked since June 2006 for the CNES formation flying experiment on the PRISMA mission. EADS ASTRIUM is responsible for the anti-collision function. This responsibility covers the design and the development of the function as a Matlab/Simulink library, as well as its functional validation and performance assessment. PRISMA is a technology in-orbit testbed mission from the Swedish National Space Board, mainly devoted to formation flying demonstration. PRISMA is made of two micro-satellites that will be launched in 2009 on a quasi-circular SSO at about 700 km of altitude. The CNES FFIORD experiment embedded on PRISMA aims at flight validating an FFRF sensor designed for formation control, and assessing its performances, in preparation to future formation flying missions such as Simbol X; FFIORD aims as well at validating various typical autonomous rendezvous and formation guidance and control algorithms. This paper presents the principles of the collision avoidance function developed by EADS ASTRIUM for FFIORD; three kinds of maneuvers were implemented and are presented in this paper with their performances.

A Macro Analysis of DoD Logistics Systems. Volume 2. Structure and Analysis of the Air Force Logistics System

DTIC Science & Technology

1977-09-01

performance measures discussed earlier is the "Engine Actuarial Data Summary" (EADS) (AFLC Form 992), compiled from D024F actuarial data. EADS is...3.2,452.3 PlyLWn M"Is, 404.670 432.603 408,553. 413.940 PMiSMA-00023 AF asm -haiw pua-flywa hma tread =100% PTtU94411 "Weul ’A101) 16,839.6 1.6,308.0...Engine Actuarial Data Summary. ENORS - 2ngine Not Operationally Ready, Supply. EOQ Items - Economic Order Quantity Items; i.e., expense-type items, not

Technology and the Transformation of Archival Description

ERIC Educational Resources Information Center

Pitti, Daniel V.

2005-01-01

The emergence of computer and network technologies has presented the archival profession with daunting challenges as well as inspiring opportunities. Archivists have been actively imagining and realizing the application of advanced technologies to their professional functions and activities. Using advanced technologies, archivists have been…

Mission Analysis for the Don Quijote Phase-A Study

NASA Technical Reports Server (NTRS)

Cano, Juan L.; Sanchez, Mariano; Cornara, Stefania; Carnelli, Ian

2007-01-01

The Don Quijote Phase-A study is a definition study funded by ESA and devoted to the analysis of the possibilities to deflect a Near Earth Object (NEO) in the range of 300-800 m diameter. DEIMOS Space S.L. and EADS Astrium have teamed up within this study to form one of the three consortia that have analyzed these aspects for ESA. Target asteroids for the mission are 1989 ML, 2002 AT4 and Apophis. This paper presents the mission analysis activities within the consortium providing: low-thrust interplanetary rendezvous Orbiter trajectories to the target asteroids, ballistic interplanetary trajectories for the Impactor, Orbiter arrival description at the asteroids, Orbiter stable orbits characterization at the asteroid, deflection determination by means of a Radio Science Experiment (RSE) as well as the mission timelines and overall mission scenarios.

Life Sciences Data Archive Scientific Development

NASA Technical Reports Server (NTRS)

Buckey, Jay C., Jr.

1995-01-01

The Life Sciences Data Archive will provide scientists, managers and the general public with access to biomedical data collected before, during and after spaceflight. These data are often irreplaceable and represent a major resource from the space program. For these data to be useful, however, they must be presented with enough supporting information, description and detail so that an interested scientist can understand how, when and why the data were collected. The goal of this contract was to provide a scientific consultant to the archival effort at the NASA-Johnson Space Center. This consultant (Jay C. Buckey, Jr., M.D.) is a scientist, who was a co-investigator on both the Spacelab Life Sciences-1 and Spacelab Life Sciences-2 flights. In addition he was an alternate payload specialist for the Spacelab Life Sciences-2 flight. In this role he trained on all the experiments on the flight and so was familiar with the protocols, hardware and goals of all the experiments on the flight. Many of these experiments were flown on both SLS-1 and SLS-2. This background was useful for the archive, since the first mission to be archived was Spacelab Life Sciences-1. Dr. Buckey worked directly with the archive effort to ensure that the parameters, scientific descriptions, protocols and data sets were accurate and useful.

Mouth development.

PubMed

Chen, Justin; Jacox, Laura A; Saldanha, Francesca; Sive, Hazel

2017-09-01

A mouth is present in all animals, and comprises an opening from the outside into the oral cavity and the beginnings of the digestive tract to allow eating. This review focuses on the earliest steps in mouth formation. In the first half, we conclude that the mouth arose once during evolution. In all animals, the mouth forms from ectoderm and endoderm. A direct association of oral ectoderm and digestive endoderm is present even in triploblastic animals, and in chordates, this region is known as the extreme anterior domain (EAD). Further support for a single origin of the mouth is a conserved set of genes that form a 'mouth gene program' including foxA and otx2. In the second half of this review, we discuss steps involved in vertebrate mouth formation, using the frog Xenopus as a model. The vertebrate mouth derives from oral ectoderm from the anterior neural ridge, pharyngeal endoderm and cranial neural crest (NC). Vertebrates form a mouth by breaking through the body covering in a precise sequence including specification of EAD ectoderm and endoderm as well as NC, formation of a 'pre-mouth array,' basement membrane dissolution, stomodeum formation, and buccopharyngeal membrane perforation. In Xenopus, the EAD is also a craniofacial organizer that guides NC, while reciprocally, the NC signals to the EAD to elicit its morphogenesis into a pre-mouth array. Human mouth anomalies are prevalent and are affected by genetic and environmental factors, with understanding guided in part by use of animal models. WIREs Dev Biol 2017, 6:e275. doi: 10.1002/wdev.275 For further resources related to this article, please visit the WIREs website. © 2017 The Authors. WIREs Developmental Biology published by Wiley Periodicals, Inc.

Early afterdepolarizations promote transmural reentry in ischemic human ventricles with reduced repolarization reserve

PubMed Central

Dutta, Sara; Mincholé, Ana; Zacur, Ernesto; Quinn, T. Alexander; Taggart, Peter; Rodriguez, Blanca

2016-01-01

Aims Acute ischemia is a major cause of sudden arrhythmic death, further promoted by potassium current blockers. Macro-reentry around the ischemic region and early afterdepolarizations (EADs) caused by electrotonic current have been suggested as potential mechanisms in animal and isolated cell studies. However, ventricular and human-specific arrhythmia mechanisms and their modulation by repolarization reserve remain unclear. The goal of this paper is to unravel multiscale mechanisms underlying the modulation of arrhythmic risk by potassium current (IKr) block in human ventricles with acute regional ischemia. Methods and results A human ventricular biophysically-detailed model, with acute regional ischemia is constructed by integrating experimental knowledge on the electrophysiological ionic alterations caused by coronary occlusion. Arrhythmic risk is evaluated by determining the vulnerable window (VW) for reentry following ectopy at the ischemic border zone. Macro-reentry around the ischemic region is the main reentrant mechanism in the ischemic human ventricle with increased repolarization reserve due to the ATP-sensitive potassium current (IK(ATP)) activation. Prolongation of refractoriness by 4% caused by 30% IKr reduction counteracts the establishment of macro-reentry and reduces the VW for reentry (by 23.5%). However, a further decrease in repolarization reserve (50% IKr reduction) is less anti-arrhythmic despite further prolongation of refractoriness. This is due to the establishment of transmural reentry enabled by electrotonically-triggered EADs in the ischemic border zone. EADs are produced by L-type calcium current (ICaL) reactivation due to prolonged low amplitude electrotonic current injected during the repolarization phase. Conclusions Electrotonically-triggered EADs are identified as a potential mechanism facilitating intramural reentry in a regionally-ischemic human ventricles model with reduced repolarization reserve. PMID:26850675

Detecting navigational deficits in cognitive aging and Alzheimer disease using virtual reality.

PubMed

Cushman, Laura A; Stein, Karen; Duffy, Charles J

2008-09-16

Older adults get lost, in many cases because of recognized or incipient Alzheimer disease (AD). In either case, getting lost can be a threat to individual and public safety, as well as to personal autonomy and quality of life. Here we compare our previously described real-world navigation test with a virtual reality (VR) version simulating the same navigational environment. Quantifying real-world navigational performance is difficult and time-consuming. VR testing is a promising alternative, but it has not been compared with closely corresponding real-world testing in aging and AD. We have studied navigation using both real-world and virtual environments in the same subjects: young normal controls (YNCs, n = 35), older normal controls (ONCs, n = 26), patients with mild cognitive impairment (MCI, n = 12), and patients with early AD (EAD, n = 14). We found close correlations between real-world and virtual navigational deficits that increased across groups from YNC to ONC, to MCI, and to EAD. Analyses of subtest performance showed similar profiles of impairment in real-world and virtual testing in all four subject groups. The ONC, MCI, and EAD subjects all showed greatest difficulty in self-orientation and scene localization tests. MCI and EAD patients also showed impaired verbal recall about both test environments. Virtual environment testing provides a valid assessment of navigational skills. Aging and Alzheimer disease (AD) share the same patterns of difficulty in associating visual scenes and locations, which is complicated in AD by the accompanying loss of verbally mediated navigational capacities. We conclude that virtual navigation testing reveals deficits in aging and AD that are associated with potentially grave risks to our patients and the community.

Behavioral and Antennal Responses of Drosophila suzukii (Diptera: Drosophilidae) to Volatiles From Fruit Extracts.

PubMed

Abraham, John; Zhang, Aijun; Angeli, Sergio; Abubeker, Sitra; Michel, Caryn; Feng, Yan; Rodriguez-Saona, Cesar

2015-04-01

Native to Southeast Asia, the spotted wing drosophila, Drosophila suzukii Matsumura (Diptera: Drosophilidae), has become a serious pest of soft-skinned fruit crops since its introduction into North America and Europe in 2008. Current monitoring strategies use baits based on fermentation products; however, to date, no fruit-based volatile blends attractive to this fly have been identified. This is particularly important because females are able to cut into the epicarp of ripening fruit for oviposition. Thus, we conducted studies to: 1) investigate the behavioral responses of adult D. suzukii to volatiles from blueberry, cherry, raspberry, and strawberry fruit extracts; 2) identify the antennally active compounds from the most attractive among the tested extracts (raspberry) using gas chromatography (GC)-mass spectrometry and coupled gas chromatography -electroantennographic detection (GC-EAD); and 3) test a synthetic blend containing the EAD-active compounds identified from raspberry extract on adult attraction. In olfactometer studies, both female and male D. suzukii were attracted to all four fruit extracts. The attractiveness of the fruit extracts ranks as: raspberry ≥ strawberry > blueberry ≥ cherry. GC analyses showed that the fruit extracts emit distinct volatile compounds. In GC-EAD experiments, 11 raspberry extract volatiles consistently elicited antennal responses in D. suzukii. In choice test bioassays, a synthetic EAD-active blend attracted more D. suzukii than a blank control, but was not as attractive as the raspberry extract. To our knowledge, this is the first report of a behaviorally and antennally active blend of host fruit volatiles attractive to D. suzukii, offering promising opportunities for the development of improved monitoring and behaviourally based management tools. © The Authors 2015. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Tales of the Supernatural: A Selected List of Recordings Made in the United States and Placed in the Archive of Folk Culture. Folk Archive Finding Aid.

ERIC Educational Resources Information Center

Delcambre, Angie C., Comp.; And Others

This finding aid is a selected list of supernatural-related narratives recorded in the United States and held in the Archive of Folk Culture of the Library of Congress. Brief descriptions of the recordings are accompanied by identification numbers. Information about listening to or ordering any of the listed recordings is available from the…

Sensing characteristics of long period gratings in hollow core fiber fabricated via electrode arc discharge

NASA Astrophysics Data System (ADS)

Iadicicco, Agostino; Cutolo, A.; Campopiano, Stefania

2014-05-01

This paper reports on the fabrication of Long Period Gratings (LPGs) in hollow-core air-silica photonic bandgap fibers (HC-PCFs) by using pressure assisted Electrode Arc Discharge (EAD) technique. In particular, the fabrication procedure relies on the combined use of EAD step, to locally heat the HC fiber, and of a static pressure (slightly higher than the external one) inside the fiber holes, to modify the holes. Here, the experimental fabrication of LPG prototypes with different periods and lengths are discussed. And, the sensitivity of LPGs in HC-PCF to environmental parameters such as strain, temperature and static pressure are presented and discussed.

The role of electric field in enhancing separation of gas molecules (H2S, CO2, H2O) on VIB modified g-C3N4 (0 0 1)

NASA Astrophysics Data System (ADS)

Wang, Fang; Li, Penghui; Wei, Shiqian; Guo, Jiaxing; Dan, Meng; Zhou, Ying

2018-07-01

In this study, the first-principles calculations were performed to investigate the adsorption behaviors of gas molecules H2S, CO2 and H2O on Cr, Mo and W modified g-C3N4 (0 0 1) surface. The results show that H2S, CO2 and H2O are physically adsorbed on the pristine g-C3N4, while the adsorption becomes chemisorbed due to the introduction of transition metals which significantly improve the interfacial electron transfer and narrow the band gap of g-C3N4 (0 0 1). Furthermore, it is found that the adsorption behaviors can be greatly influenced by the applied electric field. The adsorption energy is generally arranged in the order of Eads(H2S) > Eads(H2O) > Eads(CO2), and W/g-C3N4 (0 0 1) exhibits the best separation capability. The study could provide a versatile approach to selectively capture and separate the mixed gases in the catalytic reactions by controlling the applied intensity of electric field.

Assessment of COTS IR image simulation tools for ATR development

NASA Astrophysics Data System (ADS)

Seidel, Heiko; Stahl, Christoph; Bjerkeli, Frode; Skaaren-Fystro, Paal

2005-05-01

Following the tendency of increased use of imaging sensors in military aircraft, future fighter pilots will need onboard artificial intelligence e.g. ATR for aiding them in image interpretation and target designation. The European Aeronautic Defence and Space Company (EADS) in Germany has developed an advanced method for automatic target recognition (ATR) which is based on adaptive neural networks. This ATR method can assist the crew of military aircraft like the Eurofighter in sensor image monitoring and thereby reduce the workload in the cockpit and increase the mission efficiency. The EADS ATR approach can be adapted for imagery of visual, infrared and SAR sensors because of the training-based classifiers of the ATR method. For the optimal adaptation of these classifiers they have to be trained with appropriate and sufficient image data. The training images must show the target objects from different aspect angles, ranges, environmental conditions, etc. Incomplete training sets lead to a degradation of classifier performance. Additionally, ground truth information i.e. scenario conditions like class type and position of targets is necessary for the optimal adaptation of the ATR method. In Summer 2003, EADS started a cooperation with Kongsberg Defence & Aerospace (KDA) from Norway. The EADS/KDA approach is to provide additional image data sets for training-based ATR through IR image simulation. The joint study aims to investigate the benefits of enhancing incomplete training sets for classifier adaptation by simulated synthetic imagery. EADS/KDA identified the requirements of a commercial-off-the-shelf IR simulation tool capable of delivering appropriate synthetic imagery for ATR development. A market study of available IR simulation tools and suppliers was performed. After that the most promising tool was benchmarked according to several criteria e.g. thermal emission model, sensor model, targets model, non-radiometric image features etc., resulting in a recommendation. The synthetic image data that are used for the investigation are generated using the recommended tool. Within the scope of this study, ATR performance on IR imagery using classifiers trained on real, synthetic and mixed image sets was evaluated. The performance of the adapted classifiers is assessed using recorded IR imagery with known ground-truth and recommendations are given for the use of COTS IR image simulation tools for ATR development.

Bookbinding and the Conservation of Books. A Dictionary of Descriptive Terminology.

ERIC Educational Resources Information Center

Roberts, Matt T.; Etherington, Don

Intended for bookbinders and conservators of library and archival material and for those working in related fields, such as bibliography and librarianship, this dictionary contains definitions for the nomenclature of bookbinding and the conservation of archival material, illustrations of bookbinding equipment and processes, and biographical…

The screwworm eradication data system archives

NASA Technical Reports Server (NTRS)

Barnes, C. M.; Spaulding, R. R.; Giddings, L. E.

1977-01-01

The archives accumulated during 1 year of operation of the Satellite Temperature-Monitoring System during development of the Screwworm Eradication Data System are reported. Brief descriptions of all the kinds of tapes, as well as their potential uses, are presented. Reference is made to other documents that explain the generation of these data.

77 FR 7151 - Privacy Act of 1974: New System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-10

... Outstanding, Total Export Credit loses for last 3 years, Five Largest Export Sales Markets, Description of... litigation; h. By National Archives and Records Administration for record management inspections in its role...-275-02-01-1a approved by National Archives and Records Administration September 27, 2002. System...

Building a Collaborative Position Description Archive as a Community of Practice

ERIC Educational Resources Information Center

Keith, Brian W.; Smith, Bonnie J.; Taylor, Laurie N.

2017-01-01

Analyzing position descriptions provides insights into new and emerging trends, especially as the role of academic and research libraries continues to evolve, and new position types and new ways of organizing work emerge. Personnel officers and other library leaders frequently collaborate by sharing position descriptions in an effort to understand…

STScI Archive Manual, Version 7.0

NASA Astrophysics Data System (ADS)

Padovani, Paolo

1999-06-01

The STScI Archive Manual provides information a user needs to know to access the HST archive via its two user interfaces: StarView and a World Wide Web (WWW) interface. It provides descriptions of the StarView screens used to access information in the database and the format of that information, and introduces the use to the WWW interface. Using the two interfaces, users can search for observations, preview public data, and retrieve data from the archive. Using StarView one can also find calibration reference files and perform detailed association searches. With the WWW interface archive users can access, and obtain information on, all Multimission Archive at Space Telescope (MAST) data, a collection of mainly optical and ultraviolet datasets which include, amongst others, the International Ultraviolet Explorer (IUE) Final Archive. Both interfaces feature a name resolver which simplifies searches based on target name.

Impact of Environmental Pollution on the Preservation of Archives and Records: A RAMP Study.

ERIC Educational Resources Information Center

Pascoe, M. W.

Following a description of the essential chemical and physical structures of most archive documents, this paper examines the various pollutants that can damage these documents and gives their characteristics. The pollutants are categorized as environmental (e.g., smokes, mineral dusts); exterior gas and vapor (e.g., oxygen, water, sulphur…

Astronomical catalog desk reference, 1994 edition

NASA Technical Reports Server (NTRS)

1994-01-01

The Astronomical Catalog Desk Reference is designed to aid astronomers in locating machine readable catalogs in the Astronomical Data Center (ADC) archives. The key reference components of this document are as follows: A listing of shortened titles for all catalogs available from the ADC (includes the name of the lead author and year of publication), brief descriptions of over 300 astronomical catalogs, an index of ADC catalog numbers by subject keyword, and an index of ADC catalog numbers by author. The heart of this document is the set of brief descriptions generated by the ADC staff. The 1994 edition of the Astronomical Catalog Desk Reference contains descriptions for over one third of the catalogs in the ADC archives. Readers are encouraged to refer to this section for concise summaries of those catalogs and their contents.

Kepler Archive Manual

NASA Technical Reports Server (NTRS)

Thompson, Susan E.; Fraquelli, Dorothy; Van Cleve, Jeffrey E.; Caldwell, Douglas A.

2016-01-01

A description of Kepler, its design, performance and operational constraints may be found in the Kepler Instrument Handbook (KIH, Van Cleve Caldwell 2016). A description of Kepler calibration and data processing is described in the Kepler Data Processing Handbook (KDPH, Jenkins et al. 2016; Fanelli et al. 2011). Science users should also consult the special ApJ Letters devoted to early Kepler results and mission design (April 2010, ApJL, Vol. 713 L79-L207). Additional technical details regarding the data processing and data qualities can be found in the Kepler Data Characteristics Handbook (KDCH, Christiansen et al. 2013) and the Data Release Notes (DRN). This archive manual specifically documents the file formats, as they exist for the last data release of Kepler, Data Release 25(KSCI-19065-002). The earlier versions of the archive manual and data release notes act as documentation for the earlier versions of the data files.

A new archival infrastructure for highly-structured astronomical data

NASA Astrophysics Data System (ADS)

Dovgan, Erik; Knapic, Cristina; Sponza, Massimo; Smareglia, Riccardo

2018-03-01

With the advent of the 2020 Radio Astronomy Telescopes era, the amount and format of the radioastronomical data is becoming a massive and performance-critical challenge. Such an evolution of data models and data formats require new data archiving techniques that allow massive and fast storage of data that are at the same time also efficiently processed. A useful expertise for efficient archiviation has been obtained through data archiving of Medicina and Noto Radio Telescopes. The presented archival infrastructure named the Radio Archive stores and handles various formats, such as FITS, MBFITS, and VLBI's XML, which includes description and ancillary files. The modeling and architecture of the archive fulfill all the requirements of both data persistence and easy data discovery and exploitation. The presented archive already complies with the Virtual Observatory directives, therefore future service implementations will also be VO compliant. This article presents the Radio Archive services and tools, from the data acquisition to the end-user data utilization.

Equations for nickel-chromium wire heaters of column transfer lines in gas chromatographic-electroantennographic detection (GC-EAD).

PubMed

Byers, John A

2004-05-30

Heating of chromatographic columns, transfer lines, and other devices is often required in neuroscience research. For example, volatile compounds passing through a capillary column of a gas chromatograph (GC) can be split, with half exiting the instrument through a heated transfer line to an insect antenna or olfactory sensillum for electroantennographic detector (GC-EAD) recordings. The heated transfer line is used to prevent condensation of various chemicals in the capillary that would otherwise occur at room temperature. Construction of such a transfer line heater is described using (80/20%) nickel-chromium heating wire wrapped in a helical coil and powered by a 120/220 V ac rheostat. Algorithms were developed in a computer program to estimate the voltage at which a rheostat should be set to obtain the desired heater temperature for a specific coil. The coil attributes (radius, width, number of loops, or length of each loop) are input by the user, as well as AWG size of heating wire and desired heater temperature. The program calculates total length of wire in the helix, resistance of the wire, amperage used, and the voltage to set the rheostat. A discussion of semiochemical isolation methods using the GC-EAD and bioassays is presented.

Microfilming of the Texas Women: A Celebration of History Exhibit Archives in the Texas Woman's University Library.

ERIC Educational Resources Information Center

Nicewarner, Metta

1988-01-01

Description of the microfilming of a women's studies archive at the Texas Woman's University Library discusses: (1) project background; (2) criteria for equipment purchase; (3) equipment selected; (4) recommended resources; (5) indexing and layout decisions; (6) the filming process; and (7) the pros and cons of in-house microreproduction. (three…

Archiving of HEAO-1 data products and the creation of a general user's guide to the archive

NASA Technical Reports Server (NTRS)

Nousek, John A.

1993-01-01

The activities at Penn State University are described. Initiated at Penn State in Jan. 1989, the goal of this program was to preserve the results of the HEAO-1 mission by transforming the obsolete and disorganized data products into modern and documented forms. The result of this effort was an archive of top level data products, totalling 70 Mbytes; a general User's Guide to the archive, which is attached; and a hardcopy archive containing standardized plots and output of fits made to all the pointing data taken by the HEAO-1 A-2 LED experiment. A more detailed description of these activities is found in the following sections. Accompanying this document is a copy of the User's Guide which may provide additional detail.

Sex pheromone of orange wheat blossom midge, Sitodiplosis mosellana

NASA Astrophysics Data System (ADS)

Gries, Regine; Gries, G.; Khaskin, Grigori; King, Skip; Olfert, Owen; Kaminski, Lori-Ann; Lamb, Robert; Bennett, Robb

Pheromone extract of the female orange wheat blossom midge, Sitodiplosis mosellana (Géhin) (SM) (Diptera: Cecidomyiidae), was analyzed by coupled gas chromatographic-electroantennographic detection (GC-EAD) and GC-mass spectrometry (MS), employing fused silica columns coated with DB-5, DB-210, DB-23 or SP-1000. These analyses revealed a single, EAD-active candidate pheromone which was identified as 2,7-nonanediyl dibutyrate. In experiments in wheat fields in Saskatchewan, traps baited with (2S,7S)-2,7-nonanediyl dibutyrate attracted significant numbers of male SM. The presence of other stereoisomers did not adversely affect trap captures. Facile synthesis of stereoisomeric 2,7-nonanediyl dibutyrate will facilitate the development of pheromone-based monitoring or even control of SM populations.

The European Radiobiology Archives (ERA)--content, structure and use illustrated by an example.

PubMed

Gerber, G B; Wick, R R; Kellerer, A M; Hopewell, J W; Di Majo, V; Dudoignon, N; Gössner, W; Stather, J

2006-01-01

The European Radiobiology Archives (ERA), supported by the European Commission and the European Late Effect Project Group (EULEP), together with the US National Radiobiology Archives (NRA) and the Japanese Radiobiology Archives (JRA) have collected all information still available on long-term animal experiments, including some selected human studies. The archives consist of a database in Microsoft Access, a website, databases of references and information on the use of the database. At present, the archives contain a description of the exposure conditions, animal strains, etc. from approximately 350,000 individuals; data on survival and pathology are available from approximately 200,000 individuals. Care has been taken to render pathological diagnoses compatible among different studies and to allow the lumping of pathological diagnoses into more general classes. 'Forms' in Access with an underlying computer code facilitate the use of the database. This paper describes the structure and content of the archives and illustrates an example for a possible analysis of such data.

Linking multiple biodiversity informatics platforms with Darwin Core Archives

PubMed Central

2014-01-01

Abstract We describe an implementation of the Darwin Core Archive (DwC-A) standard that allows for the exchange of biodiversity information contained within the Scratchpads virtual research environment with external collaborators. Using this single archive file Scratchpad users can expose taxonomies, specimen records, species descriptions and a range of other data to a variety of third-party aggregators and tools (currently Encyclopedia of Life, eMonocot Portal, CartoDB, and the Common Data Model) for secondary use. This paper describes our technical approach to dynamically building and validating Darwin Core Archives for the 600+ Scratchpad user communities, which can be used to serve the diverse data needs of all of our content partners. PMID:24723785

Electroacoustic dewatering of food and other suspensions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, B.C.; Zelinski, M.S.; Criner, C.L.

1989-05-31

The food processing industry is a large user of energy for evaporative drying due to limited effectiveness of conventional mechanical dewatering machines. Battelle's Electroacoustic Dewatering (EAD) process improves the performance of mechanical dewatering machines by superimposing electric and ultrasonic fields. A two phase development program to demonstrate the benefits of EAD was carried out in cooperation with the food processing industry, the National Food Processors Association (NFPA) and two equipment vendors. In Phase I, laboratory scale studies were carried out on a variety of food suspensions. The process was scaled up to small commercial scale in Phase II. The technicalmore » feasibility of EAD for a variety of food materials, without adversely affecting the food properties, was successfully demonstrated during this phase, which is the subject of this report. Two Process Research Units (PRUs) were designed and built through joint efforts between Battelle and two equipment vendors. A 0.5-meter wide belt press was tested on apple mash, corn fiber, and corn gluten at sites provided by two food processors. A high speed citrus juice finisher (a hybrid form of screw press and centrifuge) was tested on orange pulp. These tests were carried out jointly by Battelle, equipment vendors, NFPA, and food processors. The apple and citrus juice products were analyzed by food processors and NFPA. 26 figs., 30 tabs.« less

Theoretical study on the adsorption and relative stability of conformers of L-ascorbic acid on γ - alumina (100) surface

NASA Astrophysics Data System (ADS)

Mozaffari Majd, M.; Dabbagh, H. A.; Farrokhpour, H.; Najafi Chermahini, A.

2017-11-01

The adsorption energies (Eads) and relative stabilities of selected conformers of the most stable tautomer of L-ascorbic acid (vitamin C) on the dehydroxylated γ-alumina (100) surface were calculated in both gas phase and solvent (water) using the density functional theory (DFT) method. The selected conformers were related to the different rotational angles of OH groups of L-ascorbic acid. The conformational analysis of bare tautomer in both gas and water showed that the conformer No.20 (conf. 20) and 13 (conf. 13) with the dihedral angles of H15sbnd O10sbnd C11sbnd C9 (-73°) and H20sbnd O19sbnd C9sbnd C11 (-135°) were the most stable and unstable conformers, respectively. The performed calculations in the presence of surface showed that the interaction of the conformers with the surface changes their relative stabilities and structures in both gas phase and water. The Ead of each conformer was calculated and it was determined that conf. 8 and conf. 16 have the highest value of Ead in the gas phase (-62.56 kcal/mol) and water (-54.44 kcal/mol), respectively. The optimized structure of each conformer on the surface and the number of hydrogen bonds between it and surface along with their bond lengths were determined.

Daily ambient temperature and renal colic incidence in Guangzhou, China: a time-series analysis

NASA Astrophysics Data System (ADS)

Yang, Changyuan; Chen, Xinyu; Chen, Renjie; Cai, Jing; Meng, Xia; Wan, Yue; Kan, Haidong

2016-08-01

Few previous studies have examined the association between temperature and renal colic in developing regions, especially in China, the largest developing country in the world. We collected daily emergency ambulance dispatches (EADs) for renal colic from Guangzhou Emergency Center from 1 January 2008 to 31 December 2012. We used a distributed-lag nonlinear model in addition to the over-dispersed generalized additive model to investigate the association between daily ambient temperature and renal colic incidence after controlling for seasonality, humidity, public holidays, and day of the week. We identified 3158 EADs for renal colic during the study period. This exposure-response curve was almost flat when the temperature was low and moderate and elevated when the temperature increased over 21 °C. For heat-related effects, the significant risk occurred on the concurrent day and diminished until lag day 7. The cumulative relative risk of hot temperatures (90th percentile) and extremely hot temperatures (99th percentile) over lag days 0-7 was 1.92 (95 % confidence interval, 1.21, 3.05) and 2.45 (95 % confidence interval, 1.50, 3.99) compared with the reference temperature of 21 °C. This time-series analysis in Guangzhou, China, suggested a nonlinear and lagged association between high outdoor temperatures and daily EADs for renal colic. Our findings might have important public health significance to prevent renal colic.

Cuticular hydrocarbons as sex pheromone of the bee Colletes cunicularius and the key to its mimicry by the sexually deceptive orchid, Ophrys exaltata.

PubMed

Mant, Jim; Brändli, Christoph; Vereecken, Nicolas J; Schulz, Claudia M; Francke, Wittko; Schiestl, Florian P

2005-08-01

Male Colletes cunicularius bees pollinate the orchid, Ophrys exaltata, after being sexually deceived by the orchid's odor-mimicry of the female bee's sex pheromone. We detected biologically active volatiles of C. cunicularius by using gas chromatographic-electroantennographic detection (GC-EAD) with simultaneous flame ionization detection. After identification of the target compounds by coupled gas chromatography mass spectrometry (GC-MS), we performed behavioral tests using synthetic blends of the active components. We detected 22 EAD active compounds in cuticular extracts of C. cunicularius females. Blends of straight chain, odd-numbered alkanes and (Z)-7-alkenes with 21-29 carbon atoms constituted the major biologically active compounds. Alkenes were the key compounds releasing mating behavior, especially those with (Z)-7 unsaturation. Comparison of patterns of bee volatiles with those of O. exaltata subsp. archipelagi revealed that all EAD-active compounds were also found in extracts of orchid labella. Previous studies of the mating behavior in C. cunicularius showed linalool to be an important attractant for patrolling males. We confirmed this with synthetic linalool but found that it rarely elicited copulatory behavior, in accordance with previous studies. A blend of active cuticular compounds with linalool elicited both attraction and copulation behavior in patrolling males. Thus, linalool appears to function as a long-range attractant, whereas cuticular hydrocarbons are necessary for inducing short-range mating behavior.

Project Atlas Field Definitions | NOAA Gulf Spill Restoration

Science.gov Websites

Archive Home Project Atlas Field Definitions Project Atlas Field Definitions Field Definition Project Title The Project Title as listed in the Final Early Restoration Plan and Environmental Assessment (FERP /EA). General Information: Project Description Narrative description of the project. General

Epidemiology of multiple sclerosis in US veterans: VII. Risk factors for MS.

PubMed

Kurtzke, J F; Page, W F

1997-01-01

In previous papers of this series, we explored the epidemiology of MS, examining the effects of race, sex, geography, latitude and climate, migration, age at onset, population ancestry, and individual ethnicity on the risk of MS, using an unusually large cohort of MS cases and pre-illness matched controls comprising US veterans of World War II (WWII) and the Korean Conflict (KC). In this paper, we examine primarily the effect of other factors on the risk of MS in this cohort and their relation to those previously studied. We found here that latitude tier of residence at entry into active duty (EAD), years of education, and socioeconomic class (coded from occupation) were similarly associated with MS risk among white men, black men, and white women. Higher levels of each factor showed increased MS risk. Multivariate analyses indicated that for white male WWII subjects an urban address, 9 or more years of education, uncorrected visual acuity less than 20/20 at EAD, a more northern latitude, and a higher proportion of the subject's EAD state population reporting Swedish ancestry each significantly increased the risk of MS. White male KC subjects showed roughly the same patterns, except that uncorrected visual acuity less than 20/20 was associated with lower MS risk (ancestry/ethnicity was not studied). For black male WWII and KC subjects combined, a similar analysis (omitting ancestry/ethnicity) showed that only latitude at EAD and 9 or more years of education were independently associated with a significantly higher MS risk, and for WWII plus KC white women (also without ancestry/ethnicity), only latitude was a significant risk factor in these multivariate analyses. The smaller number of subjects, especially in these last two groups, limited the power to detect statistically significant risks in these last analyses. Similarities to white men of WWII in univariate analyses for all other groups suggest that findings for the former would otherwise apply to the latter. Although the interpretations of these associations may be obscure, in addition to geography, age, sex, and race, per se, higher socioeconomic status is significantly associated with higher MS risk in black and white men and in white women in the United States.

Evaluation of the acute electrophysiologic effects of intravenous dronedarone, an amiodarone-like agent, with special emphasis on ventricular repolarization and acquired torsade de pointes arrhythmias.

PubMed

Verduyn, S C; Vos, M A; Leunissen, H D; van Opstal, J M; Wellens, H J

1999-02-01

In the anesthetized dog with complete chronic AV block (CAVB), we evaluated and compared the acute electrophysiologic effects of dronedarone i.v. (Dron, 2 times 2.5 mg/kg/10 min) and amiodarone i.v. (Amio, 2 times 5 mg/kg/10 min). This canine model with a high sensitivity for acquired torsade de pointes (TdP) provides an ideal substrate to evaluate ventricular repolarization abnormalities. Six ECG leads and two endocardial monophasic action potential (MAP) recordings in the left and right ventricle (LV and RV) were simultaneously recorded to measure QT time, action-potential duration (APD), interventricular dispersion (deltaAPD = LV(APD) - RV(APD)), early afterdepolarizations (EADs), ectopic beats (EBs), and TdP. Measurements were made at the spontaneous idioventricular rhythm (IVR) and 1,000-ms steady-state pacing. To investigate its short-term, antiarrhythmic properties, Dron was given after almokalant (0.12 mg/kg)-induced TdP. Furthermore, in another set of experiments, oral Dron (20 mg/kg, b.i.d) was given for 3 weeks to conscious CAVB dogs. Dron, i.v., shortened ventricular repolarization (QT, 435 +/- 60 to 360 +/- 55; LV(APD) 395 +/- 75 to 335 +/- 60 ms; p < 0.05), whereas IVR and ventricular effective refractory period (VERP, 225 +/- 30 to 230 +/- 30 ms) remained similar. Therefore the VERP/QT ratio increased (0.55 +/- 0.04 to 0.61 +/- 0.03; p < 0.05). Similar results were obtained with Amio, i.v.. Almokalant-induced TdP was characterized by an increased repolarization duration, deltaAPD, and EADs. Dron, i.v., suppressed the EADs, EBs, and TdP by a reduction and homogenization of repolarization (LV(APD), 505 +/- 110 to 455 +/- 80 ms, and deltaAPD, 110 +/- 55 to 65 +/- 40 ms). Long-term oral Dron increased the PP interval, CL-IVR, and QT(c) time. In contrast to oral treatment, Dron i.v. shortens ventricular repolarization parameters, resulting in suppression of EAD-dependent acquired TdP. The increased VERP/QT ratio after Dron i.v. may indicate an important second antiarrhythmic property.

Sensitive skin is highly frequent in extrinsic atopic dermatitis and correlates with disease severity markers but not necessarily with skin barrier impairment.

PubMed

Yatagai, Tsuyoshi; Shimauchi, Takatoshi; Yamaguchi, Hayato; Sakabe, Jun-Ichi; Aoshima, Masahiro; Ikeya, Shigeki; Tatsuno, Kazuki; Fujiyama, Toshiharu; Ito, Taisuke; Ojima, Toshiyuki; Tokura, Yoshiki

2018-01-01

Sensitive skin is a condition of cutaneous hypersensitivity to environmental factors. Lactic acid stinging test (LAST) is commonly used to assess sensitive skin and composed of four distinct sensations (pain, burning sensation, itch, and crawly feeling). A link between sensitive skin and barrier dysfunction has been proposed in atopic dermatitis (AD) patients. However, clinical and laboratory factors that are associated with sensitive skin remain unelucidated. To investigate relationship between sensitive skin and AD-associated markers. Forty-two Japanese AD patients and 10 healthy subjects (HS) were enrolled. AD patients were divided into extrinsic (EAD; high IgE levels) and intrinsic (IAD; normal IgE levels) types. We conducted 1% LAST by assessing the four distinct sensations and calculated the frequencies of sensitive skin in EAD, IAD, and HS. We also performed clinical AD-related tests, including transepidermal water loss (TEWL), visual analogue scale (VAS) of pruritus, and quality of life, and measured laboratory markers, including blood levels of IgE, CCL17/TARC, lactate dehydrogenase (LDH) and eosinophil counts, and concentration levels of serum Th1/Th2 cytokines. Filaggrin (FLG) mutations were examined in 21 patients. These values were subjected to correlation analyses with each of the four sensation elements. According to the standard criteria for LAST positivity, the frequencies of LAST-positive subjects were 54.8% and 10.0% in AD and HS, respectively (P=0.014). EAD patients showed a significantly (P=0.026) higher frequency of positive LAST (65.6%) than did IAD patients (20.0%). Among the four LAST sensation elements, the crawly feeling and pain scores positively correlated with VAS of pruritus, total serum IgE, mite-specific IgE, CCL17/TARC, and/or LDH. There was no association of the LAST scores with serum Th1/Th2 cytokine levels. Notably, neither TEWL nor FLG mutations correlated with LAST positivity or any sensation scores. The frequency of sensitive skin is higher in EAD than in IAD. Sensitive skin is associated with AD severity, but not necessarily with barrier condition. Copyright © 2017 Japanese Society for Investigative Dermatology. Published by Elsevier B.V. All rights reserved.

Analysis of plasmid-mediated quinolone resistance genes in clinical isolates of the tribe Proteeae from Argentina: First report of qnrD in the Americas.

PubMed

Albornoz, Ezequiel; Lucero, Celeste; Romero, Genara; Rapoport, Melina; Guerriero, Leonor; Andres, Patricia; Galas, Marcelo; Corso, Alejandra; Petroni, Alejandro

2014-12-01

To analyse the occurrence and prevalence of plasmid-mediated quinolone resistance (PMQR) genes in the tribe Proteeae, 81 isolates (65 Proteus spp., 12 Morganella morganii and 4 Providencia stuartii) consecutively collected in 66 hospitals belonging to the WHONET-Argentina Resistance Surveillance Network were studied. Of the 81 isolates, 50 (62%) were susceptible to quinolones [43/65 (66%) Proteus spp. and 7/12 (58%) M. morganii). The remaining 31 isolates (22 Proteus spp., 5 M. morganii and all P. stuartii) showed high-level resistance to nalidixic acid (NAL) and decreased susceptibility or resistance to ciprofloxacin. All NAL-resistant isolates harboured mutations associated with quinolone resistance (MAQRs) in both gyrA (S83I/R) and parC (S80I/R), and some also had MAQRs in gyrB (S464Y/F). The unique PMQR gene detected was qnrD, which was found in 2/81 isolates (Proteus mirabilis Q1084 and Proteus vulgaris Q5169), giving a prevalence of 2.5% in Proteeae. These two isolates were from different geographical regions and both harboured MAQRs in gyrA and parC. The qnrD genes were located on the related plasmids pEAD1-1 (2683bp) and pEAD1-2 (2669bp). Plasmid pEAD1-1 was 100% identical to pCGH15 and differed in only three nucleotides from pDIJ09-518a, which were previously found in clinical isolates of P. mirabilis (China) and Providencia rettgeri (France), respectively, whilst pEAD1-2 was not previously described. The extended-spectrum β-lactamase CTX-M-2 was found in 27% (22/81) of the isolates and was significantly associated with quinolone resistance but not with qnrD (only P. mirabilis Q1084 expressed CTX-M-2). This is the first report of qnrD in the Americas. Copyright © 2014 International Society for Chemotherapy of Infection and Cancer. Published by Elsevier Ltd. All rights reserved.

NASA's Planetary Data System: Support for the Delivery of Derived Data Sets at the Atmospheres Node

NASA Astrophysics Data System (ADS)

Chanover, Nancy J.; Beebe, Reta; Neakrase, Lynn; Huber, Lyle; Rees, Shannon; Hornung, Danae

2015-11-01

NASA’s Planetary Data System is charged with archiving electronic data products from NASA planetary missions that are sponsored by NASA’s Science Mission Directorate. This archive, currently organized by science disciplines, uses standards for describing and storing data that are designed to enable future scientists who are unfamiliar with the original experiments to analyze the data, and to do this using a variety of computer platforms, with no additional support. These standards address the data structure, description contents, and media design. The new requirement in the NASA ROSES-2015 Research Announcement to include a Data Management Plan will result in an increase in the number of derived data sets that are being delivered to the PDS. These data sets may come from the Planetary Data Archiving, Restoration and Tools (PDART) program, other Data Analysis Programs (DAPs) or be volunteered by individuals who are publishing the results of their analysis. In response to this increase, the PDS Atmospheres Node is developing a set of guidelines and user tools to make the process of archiving these derived data products more efficient. Here we provide a description of Atmospheres Node resources, including a letter of support for the proposal stage, a communication schedule for the planned archive effort, product label samples and templates in extensible markup language (XML), documentation templates, and validation tools necessary for producing a PDS4-compliant derived data bundle(s) efficiently and accurately.

Hydra multiple head star sensor and its in-flight self-calibration of optical heads alignment

NASA Astrophysics Data System (ADS)

Majewski, L.; Blarre, L.; Perrimon, N.; Kocher, Y.; Martinez, P. E.; Dussy, S.

2017-11-01

HYDRA is EADS SODERN new product line of APS-based autonomous star trackers. The baseline is a multiple head sensor made of three separated optical heads and one electronic unit. Actually the concept which was chosen offers more than three single-head star trackers working independently. Since HYDRA merges all fields of view the result is a more accurate, more robust and completely autonomous multiple-head sensor, releasing the AOCS from the need to manage the outputs of independent single-head star trackers. Specific to the multiple head architecture and the underlying data fusion, is the calibration of the relative alignments between the sensor optical heads. The performance of the sensor is related to its estimation of such alignments. HYDRA design is first reminded in this paper along with simplification it can bring at system level (AOCS). Then self-calibration of optical heads alignment is highlighted through descriptions and simulation results, thus demonstrating the performances of a key part of HYDRA multiple-head concept.

The Planetary Data System Web Catalog Interface--Another Use of the Planetary Data System Data Model

NASA Technical Reports Server (NTRS)

Hughes, S.; Bernath, A.

1995-01-01

The Planetary Data System Data Model consists of a set of standardized descriptions of entities within the Planetary Science Community. These can be real entities in the space exploration domain such as spacecraft, instruments, and targets; conceptual entities such as data sets, archive volumes, and data dictionaries; or the archive data products such as individual images, spectrum, series, and qubes.

Design and development of the 2m resolution camera for ROCSAT-2

NASA Astrophysics Data System (ADS)

Uguen, Gilbert; Luquet, Philippe; Chassat, François

2017-11-01

EADS-Astrium has recently completed the development of a 2m-resolution camera, so-called RSI (Remote Sensing Instrument), for the small-satellite ROCSAT-2, which is the second component of the long-term space program of the Republic of China. The National Space Program Office of Taïwan selected EADS-Astrium as the Prime Contractor for the development of the spacecraft, including the bus and the main instrument RSI. The main challenges for the RSI development were: - to introduce innovative technologies in order to meet the high performance requirements while achieving the design simplicity necessary for the mission (low mass, low power) - to have a development approach and verification compatible with the very tight development schedule This paper describes the instrument design together with the development and verification logic that were implemented to successfully meet these objectives.

In situ electron microscopy studies of electromechanical behavior in metals at the nanoscale using a novel microdevice-based system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kang, Wonmo, E-mail: wonmo.kang.ctr.ks@nrl.navy.mil; Beniam, Iyoel; Qidwai, Siddiq M.

Electrically assisted deformation (EAD) is an emerging technique to enhance formability of metals by applying an electric current through them. Despite its increasing importance in manufacturing applications, there is still an unresolved debate on the nature of the fundamental deformation mechanisms underlying EAD, mainly between electroplasticity (non-thermal effects) and resistive heating (thermal effects). This status is due to two critical challenges: (1) a lack of experimental techniques to directly observe fundamental mechanisms of material deformation during EAD, and (2) intrinsic coupling between electric current and Joule heating giving rise to unwanted thermally activated mechanisms. To overcome these challenges, we havemore » developed a microdevice-based electromechanical testing system (MEMTS) to characterize nanoscale metal specimens in transmission electron microscopy (TEM). Our studies reveal that MEMTS eliminates the effect of Joule heating on material deformation, a critical advantage over macroscopic experiments, owing to its unique scale. For example, a negligible change in temperature (<0.02 °C) is predicted at ∼3500 A/mm{sup 2}. Utilizing the attractive features of MEMTS, we have directly investigated potential electron-dislocation interactions in single crystal copper (SCC) specimens that are simultaneously subjected to uniaxial loading and electric current density up to 5000 A/mm{sup 2}. Our in situ TEM studies indicate that for SCC, electroplasticity does not play a key role as no differences in dislocation activities, such as depinning and movement, are observed.« less

Adsorption energies and prefactor determination for CH3OH adsorption on graphite.

PubMed

Doronin, M; Bertin, M; Michaut, X; Philippe, L; Fillion, J-H

2015-08-28

In this paper, we have studied adsorption and thermal desorption of methanol CH3OH on graphite surface, with the specific aim to derive from experimental data quantitative parameters that govern the desorption, namely, adsorption energy Eads and prefactor ν of the Polanyi-Wigner law. In low coverage regime, these two values are interconnected and usually the experiments can be reproduced with any couple (Eads, ν), which makes intercomparison between studies difficult since the results depend on the extraction method. Here, we use a method for determining independently the average adsorption energy and a prefactor value that works over a large range of incident methanol coverage, from a limited set of desorption curves performed at different heating rates. In the low coverage regime the procedure is based on a first order kinetic law, and considers an adsorption energy distribution which is not expected to vary with the applied heating rate. In the case of CH3OH multilayers, Eads is determined as 430 meV with a prefactor of 5 × 10(14) s(-1). For CH3OH submonolayers on graphite, adsorption energy of 470 ± 30 meV and a prefactor of (8 ± 3) × 10(16) s(-1) have been found. These last values, which do not change between 0.09 ML and 1 ML initial coverage, suggest that the methanol molecules form island-like structure on the graphite even at low coverage.

Early Learnings from the National Library of New Zealand's National Digital Heritage Archive Project

ERIC Educational Resources Information Center

Knight, Steve

2010-01-01

Purpose: The purpose of this paper is to provide a brief description of the digital preservation programme at the National Library of New Zealand. Design/methodology/approach: Following a description of the legislative and strategic context for digital preservation in New Zealand, details are provided of the system for the National Digital…

Semi-automated Data Set Submission Work Flow for Archival with the ORNL DAAC

NASA Astrophysics Data System (ADS)

Wright, D.; Beaty, T.; Cook, R. B.; Devarakonda, R.; Eby, P.; Heinz, S. L.; Hook, L. A.; McMurry, B. F.; Shanafield, H. A.; Sill, D.; Santhana Vannan, S.; Wei, Y.

2013-12-01

The ORNL DAAC archives and publishes, free of charge, data and information relevant to biogeochemical, ecological, and environmental processes. The ORNL DAAC primarily archives data produced by NASA's Terrestrial Ecology Program; however, any data that are pertinent to the biogeochemical and ecological community are of interest. The data set submission process to the ORNL DAAC has been recently updated and semi-automated to provide a consistent data provider experience and to create a uniform data product. The data archived at the ORNL DAAC must be well formatted, self-descriptive, and documented, as well as referenced in a peer-reviewed publication. If the ORNL DAAC is the appropriate archive for a data set, the data provider will be sent an email with several URL links to guide them through the submission process. The data provider will be asked to fill out a short online form to help the ORNL DAAC staff better understand the data set. These questions cover information about the data set, a description of the data set, temporal and spatial characteristics of the data set, and how the data were prepared and delivered. The questionnaire is generic and has been designed to gather input on the various diverse data sets the ORNL DAAC archives. A data upload module and metadata editor further guide the data provider through the submission process. For submission purposes, a complete data set includes data files, document(s) describing data, supplemental files, metadata record(s), and an online form. There are five major functions the ORNL DAAC performs during the process of archiving data: 1) Ingestion is the ORNL DAAC side of submission; data are checked, metadata records are compiled, and files are converted to archival formats. 2) Metadata records and data set documentation made searchable and the data set is given a permanent URL. 3) The data set is published, assigned a DOI, and advertised. 4) The data set is provided long-term post-project support. 5) Stewardship of data ensures the data are stored on state of the art computer systems with reliable backups.

SPASE: The Connection Among Solar and Space Physics Data Centers

NASA Technical Reports Server (NTRS)

Thieman, James R.; King, Todd A.; Roberts, D. Aaron

2011-01-01

The Space Physics Archive Search and Extract (SPASE) project is an international collaboration among Heliophysics (solar and space physics) groups concerned with data acquisition and archiving. Within this community there are a variety of old and new data centers, resident archives, "virtual observatories", etc. acquiring, holding, and distributing data. A researcher interested in finding data of value for his or her study faces a complex data environment. The SPASE group has simplified the search for data through the development of the SPASE Data Model as a common method to describe data sets in the various archives. The data model is an XML-based schema and is now in operational use. There are both positives and negatives to this approach. The advantage is the common metadata language enabling wide-ranging searches across the archives, but it is difficult to inspire the data holders to spend the time necessary to describe their data using the Model. Software tools have helped, but the main motivational factor is wide-ranging use of the standard by the community. The use is expanding, but there are still other groups who could benefit from adopting SPASE. The SPASE Data Model is also being expanded in the sense of providing the means for more detailed description of data sets with the aim of enabling more automated ingestion and use of the data through detailed format descriptions. We will discuss the present state of SPASE usage and how we foresee development in the future. The evolution is based on a number of lessons learned - some unique to Heliophysics, but many common to the various data disciplines.

Fallon, Nevada FORGE Distinct Element Reservoir Modeling

DOE Data Explorer

Blankenship, Doug; Pettitt, Will; Riahi, Azadeh; Hazzard, Jim; Blanksma, Derrick

2018-03-12

Archive containing input/output data for distinct element reservoir modeling for Fallon FORGE. Models created using 3DEC, InSite, and in-house Python algorithms (ITASCA). List of archived files follows; please see 'Modeling Metadata.pdf' (included as a resource below) for additional file descriptions. Data sources include regional geochemical model, well positions and geometry, principal stress field, capability for hydraulic fractures, capability for hydro-shearing, reservoir geomechanical model-stimulation into multiple zones, modeled thermal behavior during circulation, and microseismicity.

NASA participation in the 1980 PEPE/NEROS project: Data archive

NASA Technical Reports Server (NTRS)

Brewer, D. A.; Remsberg, E. E.; Loar, G. R.; Bendura, R. J.

1982-01-01

Eight experimental air quality measurement systems were investigated during July and August 1980 as part of the EPA PEPE/NEROS fiel measurement program. Data from those efforts have been entered into an archive that may be accessed by other researchers. The data sets consists of airborne measurements of regional mixed layer heights and aerosol and ozone distributions as well as point measurements of meteorological parameters and ozone obtained during diurnal transitions in the planetary boundary layer. This report gives a discussion of each measurement system, a preliminary assessment of data quality, a description of the archive format for each data set, and a summary of several proposed scientific studies which will utilize these data.

Discovery and Biochemical Characterization of PlyP56, PlyN74, and PlyTB40—Bacillus Specific Endolysins

PubMed Central

Etobayeva, Irina; Linden, Sara B.; Alem, Farhang; Rizkalla, Lucas; Temple, Louise; Hakami, Ramin M.

2018-01-01

Three Bacillus bacteriophage-derived endolysins, designated PlyP56, PlyN74, and PlyTB40, were identified, cloned, purified, and characterized for their antimicrobial properties. Sequence alignment reveals these endolysins have an N-terminal enzymatically active domain (EAD) linked to a C-terminal cell wall binding domain (CBD). PlyP56 has a Peptidase_M15_4/VanY superfamily EAD with a conserved metal binding motif and displays biological dependence on divalent ions for activity. In contrast, PlyN74 and PlyTB40 have T7 lysozyme-type Amidase_2 and carboxypeptidase T-type Amidase_3 EADs, respectively, which are members of the MurNAc-LAA superfamily, but are not homologs and thus do not have a shared protein fold. All three endolysins contain similar SH3-family CBDs. Although minor host range differences were noted, all three endolysins show relatively broad antimicrobial activity against members of the Bacillus cereus sensu lato group with the highest lytic activity against B. cereus ATCC 4342. Characterization studies determined the optimal lytic activity for these enzymes was at physiological pH (pH 7.0–8.0), over a broad temperature range (4–55 °C), and at low concentrations of NaCl (<50 mM). Direct comparison of lytic activity shows the PlyP56 enzyme to be twice as effective at lysing the cell wall peptidoglycan as PlyN74 or PlyTB40, suggesting PlyP56 is a good candidate for further antimicrobial development as well as bioengineering studies. PMID:29883383

Pediatric Donor to Adult Recipients in Donation After Cardiac Death Liver Transplantation: A Single-Center Experience.

PubMed

Lan, C; Song, J L; Yan, L N; Yang, J Y; Wen, T F; Li, B; Xu, M Q

The impact of using liver allografts from donors who are younger than 14 years at the time of donation after cardiac death (DCD) liver transplantation in terms of early allograft dysfunction (EAD) and graft survival is undefined. To determine if adults undergoing DCD liver transplantation who receive a graft from a donor age younger than or equal to 13 years have similar outcomes to recipients of organs from older than 18-year-old donors. Records from adult patients undergoing DCD liver transplantation between March 2012 and December 2015 who received whole grafts from donors after cardiac death were reviewed. Patients with donors younger than or equal to 13 years (group 1) and older than 18 years (group 2) were compared for EAD rates, hepatic artery thrombosis (HAT), and graft survival. Records of 60 DCD liver transplantation patients were analyzed. The 90-day and 1-year graft survival rate of both groups was 90% versus 96% (P = .427) and 80% versus 84% (P = .668), respectively. The EAD rates of groups 1 and 2 were 30% versus 34% (P = .806). The incidence of HAT was 20% in group 1 compared with 12% in group 2 (P = .610). Also, 0.7% < graft to recipient weight ratio (GRWR) <0.8% was also usable for pediatric donor to adult recipients. Whole liver grafts from donors younger than or equal to 13 years can potentially be used in selected size-matched (GRWR >0.7%) DCD adult recipients. Copyright © 2017 Elsevier Inc. All rights reserved.

Transient hyperglycemia during liver transplantation does not affect the early graft function.

PubMed

Blasi, Annabel; Beltran, Joan; Martin, Nuria; Martinez-Pallí, Graciela; Lozano, Juan J; Balust, Jaume; Torrents, Abigail; Taura, Pilar

2015-01-01

Background and rationale for the study. Hyperglycemia after graft reperfusion is a consistent finding in liver transplantation (LT) that remains poorly studied. We aim to describe its appearance in LT recipients of different types of grafts and its relation to the graft function. 436 LT recipients of donors after brain death (DBD), donors after cardiac death (DCD), and familial amyloidotic polyneuropathy (FAP) donors were reviewed. Serum glucose was measured at baseline, during the anhepatic phase, after graft reperfusion, and at the end of surgery. Early graft dysfunction (EAD) was assessed by Olthoff criteria. Caspase-3, IFN-γ, IL1β, and IL6 gene expression were measured in liver biopsy. The highest increase in glucose levels after reperfusion was observed in FAP LT recipients and the lowest in DCD LT recipients. Glucose level during the anhepatic phase was the only modifiable predictive variable of hyperglycemia after reperfusion. No relation was found between hyperglycemia after reperfusion and EAD. However, recipients with the highest glucose levels after reperfusion tended to achieve the best glucose control at the end of surgery and those who were unable to control the glucose value after reperfusion showed EAD more frequently. The highest levels of caspase-3 were found in recipients with the lowest glucose values after reperfusion. In conclusion, glucose levels increased after graft reperfusion to a different extent according to the donor type. Contrary to general belief, transient hyperglycemia after reperfusion does not appear to impact negatively on the liver graft function and could even be suggested as a marker of graft quality.

Host Plant Species Differentiation in a Polyphagous Moth: Olfaction is Enough.

PubMed

Conchou, Lucie; Anderson, Peter; Birgersson, Göran

2017-08-01

Polyphagous herbivorous insects need to discriminate suitable from unsuitable host plants in complex plant communities. While studies on the olfactory system of monophagous herbivores have revealed close adaptations to their host plant's characteristic volatiles, such adaptive fine-tuning is not possible when a large diversity of plants is suitable. Instead, the available literature on polyphagous herbivore preferences suggests a higher level of plasticity, and a bias towards previously experienced plant species. It is therefore necessary to take into account the diversity of plant odors that polyphagous herbivores encounter in the wild in order to unravel the olfactory basis of their host plant choice behaviour. In this study we show that a polyphagous moth, Spodoptera littoralis, has the sensory ability to distinguish five host plant species using olfaction alone, this being a prerequisite to the ability to make a choice. We have used gas chromatography mass spectrometry (GC-MS) and gas chromatography electroantennographic detection (GC-EAD) in order to describe host plant odor profiles as perceived by S. littoralis. We find that each plant emits specific combinations and proportions of GC-EAD active volatiles, leading to statistically distinct profiles. In addition, at least four of these plants show GC-EAD active compound proportions that are conserved across individual plants, a characteristic that enables insects to act upon previous olfactory experiences during host plant choice. By identifying the volatiles involved in olfactory differentiation of alternative host plants by Spodoptera littoralis, we set the groundwork for deeper investigations of how olfactory perceptions translate into behaviour in polyphagous herbivores.

Triggered Firing and Atrial Fibrillation in Transgenic Mice With Selective Atrial Fibrosis Induced by Overexpression of TGF-β1

PubMed Central

Choi, Eue-Keun; Chang, Po-Cheng; Lee, Young-Soo; Lin, Shien-Fong; Zhu, Wuqiang; Maruyama, Mitsunori; Fishbein, Michael C.; Chen, Zhenhui; der Lohe, Michael Rubart-von; Field, Loren J.; Chen, Peng-Sheng

2013-01-01

Background Calcium transient triggered firing (CTTF) is induced by large intracellular calcium (Cai) transient and short action potential duration (APD). We hypothesized that CTTF underlies the mechanisms of early afterdepolarization (EAD) and spontaneous recurrent atrial fibrillation (AF) in transgenic (Tx) mice with overexpression of transforming growth factor β1 (TGF-β1). Methods and Results MHC-TGFcys33ser Tx mice develop atrial fibrosis because of elevated levels of TGF-β1. We studied membrane potential and Cai transients of isolated superfused atria from Tx and wild-type (Wt) littermates. Short APD and persistently elevated Cai transients promoted spontaneous repetitive EADs, triggered activity and spontaneous AF after cessation of burst pacing in Tx but not Wt atria (39% vs. 0%, P=0.008). We were able to map optically 4 episodes of spontaneous AF re-initiation. All first and second beats of spontaneous AF originated from the right atrium (4/4, 100%), which is more severely fibrotic than the left atrium. Ryanodine and thapsigargin inhibited spontaneous re-initiation of AF in all 7 Tx atria tested. Western blotting showed no significant changes of calsequestrin or sarco/endoplasmic reticulum Ca2+-ATPase 2a. Conclusions Spontaneous AF may occur in the Tx atrium because of CTTF, characterized by APD shortening, prolonged Cai transient, EAD and triggered activity. Inhibition of Ca2+ release from the sarcoplasmic reticulum suppressed spontaneous AF. Our results indicate that CTTF is an important arrhythmogenic mechanism in TGF-β1 Tx atria. PMID:22447020

[Posterior decompression of the craniovertebral junction in syringomyelia combined with Chiari-1 malformation in children].

PubMed

Sanakoeva, A V; Korshunov, A E; Kadyrov, Sh U; Khukhlaeva, E A; Kushel', Yu V

to develop the algorithm for defining the amount of posterior decompression of the craniovertebral junction in children with syringomyelia combined with Chiari-1 malformation. Sixty eight children with syringomyelia and Chiari-1 malformation, under age of 18 years, underwent posterior decompression of the craniovertebral junction (PDCVJ) in the period from January 2001 to June 2016. Seven (10%) patients underwent extradural decompression (EDD), 16 (24%) patients underwent extra-arachnoid duraplasty (EAD), 25 (37%) patients underwent intra-arachnoid dissection (IAD) and duraplasty, and 20 (29%) patients underwent PDCVJ and placement of a fourth ventricle-subarachnoid shunt. Clinical improvement occurred in 85% of patients, and stabilization was observed in 11% of patients. Syringomyelia regressed in 78% of cases. There were no complications associated with EDD; however, re-operation was required in 3 (43%) cases. In the case of EAD, treatment results were satisfactory in 11 (79%) patients; re-operation was required in 2 (12.5%) cases; there were no complications in the early postoperative period. The highest complication rate of 6 (30%) cases was associated with shunt placement and duraplasty. However, long-term results in this group of patients were satisfactory in 16 (94%) cases, and MRI-based positive changes were observed in 100% of cases. According to our analysis, EAD is the method of choice for PDCVJ in children with syringomyelia and Chiari-1 malformation without myelopathy symptoms. In the presence of myelopathy symptoms, intra-arachnoid dissection (with or without shunting) is an acceptable alternative. To our opinion, the use of EDD in syringomyelia is unadvisable.

Liver Transplantation and Donor Body Mass Index >30: Use or Refuse?

PubMed

Andert, Anne; Becker, Niklas; Ulmer, Florian; Schöning, Wenzel; Hein, Marc; Rimek, Alexandra; Neumann, Ulf; Schmeding, Maximilian

2016-03-31

Organ shortage is a major problem in liver transplantation. The use of extended criteria donors has become the most important strategy for increasing the donor pool. However, the role of donor body mass index has not yet been thoroughly investigated. The aim of our study was to compare outcomes after liver transplantation in patients who received a liver from a donor with a BMI <30, 30-39, and ≥40, with special regard to the incidence of early allograft dysfunction (EAD) and primary non-function (PNF). One hundred and sixty-three patients who underwent liver transplantation at the University Hospital Aachen between June 2010 and January 2014 were included in this analysis. The outcome of liver transplantation was evaluated by the 30-day and 1-year patient and graft survival rates and the incidences of post-reperfusion syndrome (PRS), EAD, and PNF. The BMI 30-39 group had a higher incidence of EAD than the BMI <30 and BMI ≥40 groups. We observed 5 cases of PNF in the BMI <30 group. The incidence of acute renal failure was significantly higher in the BMI 30-39 and BMI ≥40 groups than in the BMI <30 group. Patient and graft survival did not differ significantly among the 3 groups. Based on the findings of this study, grafts from obese donors with a BMI >30 can be safely transplanted. Therefore, the donor pool can be enlarged to include such obese donors without a negative impact on the long-term patient outcome after liver transplantation.

Extra-articular deformities in arthritic knees-a grueling challenge for arthroplasty surgeons: An evidence-based update

PubMed Central

Khanna, Vishesh; Sambandam, Senthil N.; Ashraf, Munis; Mounasamy, Varatharaj

2018-01-01

Critical to the success of a total knee arthroplasty (TKA) is the anatomical alignment. This may appear as a challenge in an extra-articular deformity (EAD) that may be inherent in certain people or result from fracture malunion, congenital disorders, nutritional, metabolic and infective causes. This appraisal aimed at providing the reader with an up-todate overview of the research carried out on, and existent evidence of EAD correction while planning a TKA. We reviewed the current English literature on TKA in extra-articular knee deformities. Among the published data, a common initial approach of mandatory clinical and radiological assessment emerges as an obligatory step while handling cases with EAD. While several methods of managing the deformity and arthritis have been described, a broad division into intra-articular and extra-articular means can be deciphered. The relatively old-school, yet reliable thought process of extra-articular correction allows an all-inclusive restoration of alignment with the inherent complications related to the necessary osteotomy. A cohort of younger and more venturesome surgeons seem inclined towards performing navigated, intra-articular correction for mild to moderate and sometimes, severe deformities. The crux of the matter lies is obtaining a well-balanced knee without violating the all-important cruciates. Restoring the patient’s ambulatory status seems sooner with the intra-articular methods which are also more precise in determining the axes and while removing minimum bone. Greatest satisfaction is accomplished in those with less grotesque, rotationallyaligned knees while meticulously balancing soft-tissues and encouraging earlier weightbearing. PMID:29564077

GORGONA - the characteristic of the software system.

NASA Astrophysics Data System (ADS)

Artim, M.; Zejda, M.

A description of the new software system is given. The GORGONA system is established to the processing, making and administration of archives of periodic variable stars observations, observers and observed variable stars.

75 FR 65383 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-Telemanagement Forum

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-22

..., CA; Compunet Services, Inc., Stockbridge, GA; Cordys, Putten, THE NETHERLANDS; Cosmo Bulgaria Mobile... Inc. to Cloud.com , Cupertino, CA; Globul to Cosmo Bulgaria Mobile EAD(GloBul), Sofia, BULGARIA; CTBC...

Coexistence of Bilirubin ≥10 mg/dL and Prothrombin Time-International Normalized Ratio ≥1.6 on Day 7: A Strong Predictor of Early Graft Loss After Living Donor Liver Transplantation.

PubMed

Okamura, Yusuke; Yagi, Shintaro; Sato, Toshiya; Hata, Koichiro; Ogawa, Eri; Yoshizawa, Atsushi; Kamo, Naoko; Yamashiki, Noriyo; Okajima, Hideaki; Kaido, Toshimi; Uemoto, Shinji

2018-03-01

Early allograft dysfunction (EAD) defined by serum total bilirubin (TB) of 10 mg/dL or greater or prothrombin time-international normalized ratio (PT-INR) of 1.6 or greater on postoperative day 7 (POD 7) or aminotransferase greater than 2000 IU/L within the first week, is associated with early graft loss after deceased-donor liver transplantation. We aimed to determine the prognostic impact of the EAD definition in living-donor liver transplantation (LDLT). We analyzed the validity of the EAD definition and its impact on early graft survival in 260 adult recipients who underwent primary LDLT. Eighty-four (32.3%) patients met the EAD criteria; 59 (22.7%) and 46 (17.7%) patients had TB of 10 mg/dL or greater and PT-INR of 1.6 or greater on POD 7, respectively, and 22 (8.5%) patients satisfied both criteria. Graft survival differed significantly when stratified according to TB of 10 mg/dL or greater and PT-INR of 1.6 or greater (P < 0.0001). PT-INR of 1.6 or greater resulted in higher graft mortality (risk ratio [RR], 3.87; P < 0.0001 at 90 days; RR, 2.97; P < 0.0001 at 180 days), as did TB of 10 mg/dL or greater (RR, 1.89; P = 0.027 at 90 days; RR, 1.91; P = 0.006 at 180 days). Coexistence of TB of 10 mg/dL or greater and PT-INR of 1.6 or greater was strongly associated with early graft loss (59.1%, RR, 6.97 at 90 days; 68.2%; RR, 5.75 at 180 days). In Cox regression analysis, PT-INR of 1.6 or greater and TB of 10 mg/dL or greater on POD 7 were significant risk factors for early graft loss (hazard ratio, 4.10; 95% confidence interval, 2.35-7.18; P < 0.0001, and hazard ratio, 2.43; 95% confidence interval, 1.39-4.24; P = 0.0018, respectively). TB of 10 mg/dL or greater and/or PT-INR of 1.6 or greater on POD 7 predicted early graft loss after LDLT, and their coexistence worsened patient outcomes.

Protein Data Bank Japan (PDBj): maintaining a structural data archive and resource description framework format

PubMed Central

Kinjo, Akira R.; Suzuki, Hirofumi; Yamashita, Reiko; Ikegawa, Yasuyo; Kudou, Takahiro; Igarashi, Reiko; Kengaku, Yumiko; Cho, Hasumi; Standley, Daron M.; Nakagawa, Atsushi; Nakamura, Haruki

2012-01-01

The Protein Data Bank Japan (PDBj, http://pdbj.org) is a member of the worldwide Protein Data Bank (wwPDB) and accepts and processes the deposited data of experimentally determined macromolecular structures. While maintaining the archive in collaboration with other wwPDB partners, PDBj also provides a wide range of services and tools for analyzing structures and functions of proteins, which are summarized in this article. To enhance the interoperability of the PDB data, we have recently developed PDB/RDF, PDB data in the Resource Description Framework (RDF) format, along with its ontology in the Web Ontology Language (OWL) based on the PDB mmCIF Exchange Dictionary. Being in the standard format for the Semantic Web, the PDB/RDF data provide a means to integrate the PDB with other biological information resources. PMID:21976737

A Complete Public Archive for the Einstein Imaging Proportional Counter

NASA Technical Reports Server (NTRS)

Helfand, David J.

1996-01-01

Consistent with our proposal to the Astrophysics Data Program in 1992, we have completed the design, construction, documentation, and distribution of a flexible and complete archive of the data collected by the Einstein Imaging Proportional Counter. Along with software and data delivered to the High Energy Astrophysics Science Archive Research Center at Goddard Space Flight Center, we have compiled and, where appropriate, published catalogs of point sources, soft sources, hard sources, extended sources, and transient flares detected in the database along with extensive analyses of the instrument's backgrounds and other anomalies. We include in this document a brief summary of the archive's functionality, a description of the scientific catalogs and other results, a bibliography of publications supported in whole or in part under this contract, and a list of personnel whose pre- and post-doctoral education consisted in part in participation in this project.

Image acquisition unit for the Mayo/IBM PACS project

NASA Astrophysics Data System (ADS)

Reardon, Frank J.; Salutz, James R.

1991-07-01

The Mayo Clinic and IBM Rochester, Minnesota, have jointly developed a picture archiving, distribution and viewing system for use with Mayo's CT and MRI imaging modalities. Images are retrieved from the modalities and sent over the Mayo city-wide token ring network to optical storage subsystems for archiving, and to server subsystems for viewing on image review stations. Images may also be retrieved from archive and transmitted back to the modalities. The subsystems that interface to the modalities and communicate to the other components of the system are termed Image Acquisition Units (LAUs). The IAUs are IBM Personal System/2 (PS/2) computers with specially developed software. They operate independently in a network of cooperative subsystems and communicate with the modalities, archive subsystems, image review server subsystems, and a central subsystem that maintains information about the content and location of images. This paper provides a detailed description of the function and design of the Image Acquisition Units.

Aero/fluids database system

NASA Technical Reports Server (NTRS)

Reardon, John E.; Violett, Duane L., Jr.

1991-01-01

The AFAS Database System was developed to provide the basic structure of a comprehensive database system for the Marshall Space Flight Center (MSFC) Structures and Dynamics Laboratory Aerophysics Division. The system is intended to handle all of the Aerophysics Division Test Facilities as well as data from other sources. The system was written for the DEC VAX family of computers in FORTRAN-77 and utilizes the VMS indexed file system and screen management routines. Various aspects of the system are covered, including a description of the user interface, lists of all code structure elements, descriptions of the file structures, a description of the security system operation, a detailed description of the data retrieval tasks, a description of the session log, and a description of the archival system.

ADVANCED REMOTE SENSING MONITORING OF MINE WASTE

EPA Science Inventory

The OEI-EAD and NERL-ESD have been cooperating on development of monitoring technologies and research to better use remote sensor-derived information and to ultimately disseminate that information to users. This work has focused on NASA'S airborne advanced remote sensor systems ...

The SPASE Data Model for Heliophysics Data: Is it Working?

NASA Technical Reports Server (NTRS)

Thieman, James; King, Todd; Roberts, Aaron

2011-01-01

The Space Physics Archive Search and Extract (SPASE) Data Model was developed to provide a metadata standard for describing Heliophysics (Space and Solar Physics) data within that science discipline. The SPASE Data Model has matured over the many years of its creation and is presently represented by Version 2.2.1. Information about SPASE can be obtained from the website group.org. The Data Model defines terms and values as well as the relationships between them in order to describe the data resources in the Heliophysics data environment. This data environment is quite complex, consisting of Virtual Observatories, Resident Archives, Data Providers, Partnering Data Centers, Services, Final Archives, and a Deep Archive. SPASE is the metadata language standard intended to permeate the complexity and provide a common method of obtaining and understanding data. Is it working in this capacity? SPASE has been used to describe a wide range of data. Examples range from ground-based magnetometer data to interplanetary satellite measurements to space weather model results. Has it achieved the goal of making the data easier to find and use? To find data of interest it is necessary that all the data of importance be described using the SPASE Data Model. Within the part of the data community associated with NASA (supported through NASA funding) there are obligations to use SPASE and (0 describe the old and new data using the SPASE XML schema. Although this pan of the community is not near 100% compliance with the mandate, there is good progress being made and the goal should be reachable in the future. Outside of the NASA data community there is still work to be done to convince the international community that SPASE descriptions are w011h the cost of their generation. Some of these groups such as Cluster, HELlO, GAIA, NOAA/NGDe. CSSDP, VSTO, SuperMAG, and IUGONET have agreed to use SPASE. but there are still other groups of importance that need (0 be reached. It is also assumed that the terminology is sufficiently broad and the descriptions are sufficiently complete that researchers needing data of a specific type or from a specific period can find and acquire what they need. A valid SPASE description can be very brief or very thorough depending on the willingness of the author to spend the time necessary to make the description useful. There is evidence that users are finding what they need through the SPASE descriptions, and this standard is a big step forward in Heliophysics data location. Does SPASE make it easier to use the data once they are found,) Thorough descriptions of data using SPASE can describe the data down to the level of individual parameters and exactly how the data are organized and stored. Should the SPASE data descriptions be written in such a way that they can be automatically ingested and understood by software tools'? Heliophysics instruments are becoming morc versatile all the time and the complexity of the data makes it tedious and time consuming to write SPASE descriptions with this level of sophistication even with the improvement of the tools used to generate the descriptions. Is it better to just write human-readable descriptions of the data at the parameter level or to refer to references that provide this information? This is a debate that is presently taking place and software is being developed to test what is possible.

Using the Stereotype Content Model to examine group depictions in Fascism: An Archival Approach.

PubMed

Durante, Federica; Volpato, Chiara; Fiske, Susan T

2010-04-01

The Stereotype Content Model (SCM) suggests potentially universal intergroup depictions. If universal, they should apply across history in archival data. Bridging this gap, we examined social groups descriptions during Italy's Fascist era. In Study 1, articles published in a Fascist magazine- La Difesa della Razza -were content analyzed, and results submitted to correspondence analysis. Admiration prejudice depicted ingroups; envious and contemptuous prejudices depicted specific outgroups, generally in line with SCM predictions. No paternalistic prejudice appeared; historical reasons might explain this finding. Results also fit the recently developed BIAS Map of behavioral consequences. In Study 2, ninety-six undergraduates rated the content-analysis traits on warmth and competence, without knowing their origin. They corroborated SCM's interpretations of the archival data.

Food addiction, orthorexia, and food-related stress among dietetics students.

PubMed

Grammatikopoulou, Maria G; Gkiouras, Konstantinos; Markaki, Anastasia; Theodoridis, Xenophon; Tsakiri, Vasiliki; Mavridis, Pantelis; Dardavessis, Theodore; Chourdakis, Michael

2018-05-19

Health sciences, and in particular Nutrition and Dietetics students, have been shown to exhibit an increased prevalence of disordered eating. The aim of the present cross-sectional study was to evaluate other specified feeding and eating disorders (OSFEDs), including stress-related eating, food addiction, and orthorexia, in relation to the dietary intake, among nutrition/dietetics students. A total of 176 undergraduate students from a Department of Nutrition and Dietetics, in Greece, participated in the study. Dietary intake was recorded, and the prevalence of Eating and Appraisal Due to Emotion and Stress (EADES), food addiction (with the modified Yale Food Addition scale mYFAS), and orthorexia were assessed. Chi-square and t tests were performed between sexes, orthorexic and non-orthorexic students, as well as between food-addicted and non-addicted participants. Multiple linear regression analysis assessed relationships between energy intake, BMI or waist circumference, and the food-related psychometric scales. Among participating students, 4.5% had food addiction and 68.2% demonstrated orthorexia. No differences were observed between men and women, concerning the prevalence of food addiction and orthorexia, the sum of mYFAS symptoms, or individual EADES factors. Orthorexic students exhibited increased BMI, reduced energy, and saturated fat intake. In addition, orthorexic men consumed more vegetables. Multiple linear regression analysis revealed that orthorexic behavior was associated with increased BMI, waist circumference and energy intake. Lower BMI was associated with increasing ability to cope with emotion-and-stress-related eating and increasing appraisal of ability and resources to cope with emotions and stress. Emotion-and-stress-related eating was negatively associated with BMI. Appraisal of ability and resources to cope with emotions and stress was associated with the energy intake. Finally, age was positively correlated with the appraisal of outside stressors/influences, indicating increased ability to cope with outside stressors among older students. The study shows that despite the suggested interventions, the problem of OSFEDs among nutrition and dietetics students is still valid. Regular screening, counseling, and education is needed to reduce its prevalence. Level V, cross-sectional descriptive study.

76 FR 21225 - Documents Acceptable for Employment Eligibility Verification

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-15

... identity and employment authorization documents (EADs) and receipts that employees may present to employers... \\1\\ (hereinafter collectively referred to as ``employer(s)'') are required to verify the identity and... as acceptable for establishing identity and employment authorization. The employer must examine the...

75 FR 81424 - Airworthiness Directives; Sikorsky Aircraft Corporation (Sikorsky) Model S76A, B, and C Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-28

.... The EAD requires inspecting the LITEF Attitude Heading and Reference System (AHRS) unit of the...: Model S-76A, B, and C helicopters, with LITEF LCR-100, Attitude Heading and Reference System (AHRS) Unit...

Managing an Archive of Images

NASA Technical Reports Server (NTRS)

Andres, Vince; Walter, David; Hallal, Charles; Jones, Helene; Callac, Chris

2004-01-01

The SSC Multimedia Archive is an automated electronic system to manage images, acquired both by film and digital cameras, for the Public Affairs Office (PAO) at Stennis Space Center (SSC). Previously, the image archive was based on film photography and utilized a manual system that, by today s standards, had become inefficient and expensive. Now, the SSC Multimedia Archive, based on a server at SSC, contains both catalogs and images for pictures taken both digitally and with a traditional, film-based camera, along with metadata about each image. After a "shoot," a photographer downloads the images into the database. Members of the PAO can use a Web-based application to search, view and retrieve images, approve images for publication, and view and edit metadata associated with the images. Approved images are archived and cross-referenced with appropriate descriptions and information. Security is provided by allowing administrators to explicitly grant access privileges to personnel to only access components of the system that they need to (i.e., allow only photographers to upload images, only PAO designated employees may approve images).

The Planck Telescope reflectors

NASA Astrophysics Data System (ADS)

Stute, Thomas

2004-09-01

The mechanical division of EADS-Astrium GmbH, Friedrichshafen is currently engaged with the development, manufacturing and testing of the advanced dimensionally stable composite reflectors for the ESA satellite borne telescope Planck. The objective of the ESA mission Planck is to analyse the first light that filled the universe, the cosmic microwave background radiation. Under contract of the Danish Space Research Institute and ESA EADS-Astrium GmbH is developing the all CFRP primary and secondary reflectors for the 1.5-metre telescope which is the main instrument of the Planck satellite. The operational frequency ranges from to 25 GHz to 1000 GHz. The demanding high contour accuracy and surface roughness requirements are met. The design provides the extreme dimensional stability required by the cryogenic operational environment at around 40 K. The elliptical off-axis reflectors display a classical lightweight sandwich design with CFRP core and facesheets. Isostatic mounts provide the interfaces to the telescope structure. Protected VDA provides the reflecting surface. The manufacturing is performed at the Friedrichshafen premises of EADS-Space Transportation GmbH, the former Dornier composite workshops. Advanced manufacturing technologies like true angle lay-up by CNC fibre placement and filament winding are utilized. The protected coating is applied at the CAHA facilities at the Calar Alto Observatory, Spain. The exhaustive environmental testing is performed at the facilities of IABG, Munich (mechanical testing) and for the cryo-optical tests at CSL Liege. The project is in advanced state with both Qualification Models being under environmental testing. The flight models will be delivered in 2004. The paper gives an overview over the requirements and the main structural features how these requirements are met. Special production aspects and available test results are reported.

Availability of human induced pluripotent stem cell-derived cardiomyocytes in assessment of drug potential for QT prolongation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nozaki, Yumiko, E-mail: yumiko-nozaki@ds-pharma.co.jp; Honda, Yayoi, E-mail: yayoi-honda@ds-pharma.co.jp; Tsujimoto, Shinji, E-mail: shinji-tsujimoto@ds-pharma.co.jp

2014-07-01

Field potential duration (FPD) in human-induced pluripotent stem cell-derived cardiomyocytes (hiPS-CMs), which can express QT interval in an electrocardiogram, is reported to be a useful tool to predict K{sup +} channel and Ca{sup 2+} channel blocker effects on QT interval. However, there is no report showing that this technique can be used to predict multichannel blocker potential for QT prolongation. The aim of this study is to show that FPD from MEA (Multielectrode array) of hiPS-CMs can detect QT prolongation induced by multichannel blockers. hiPS-CMs were seeded onto MEA and FPD was measured for 2 min every 10 min formore » 30 min after drug exposure for the vehicle and each drug concentration. I{sub Kr} and I{sub Ks} blockers concentration-dependently prolonged corrected FPD (FPDc), whereas Ca{sup 2+} channel blockers concentration-dependently shortened FPDc. Also, the multichannel blockers Amiodarone, Paroxetine, Terfenadine and Citalopram prolonged FPDc in a concentration dependent manner. Finally, the I{sub Kr} blockers, Terfenadine and Citalopram, which are reported to cause Torsade de Pointes (TdP) in clinical practice, produced early afterdepolarization (EAD). hiPS-CMs using MEA system and FPDc can predict the effects of drug candidates on QT interval. This study also shows that this assay can help detect EAD for drugs with TdP potential. - Highlights: • We focused on hiPS-CMs to replace in vitro assays in preclinical screening studies. • hiPS-CMs FPD is useful as an indicator to predict drug potential for QT prolongation. • MEA assay can help detect EAD for drugs with TdP potentials. • MEA assay in hiPS-CMs is useful for accurately predicting drug TdP risk in humans.« less

Astrium Technological Roadmaps for the Next Generation of Launchers Challenges

NASA Astrophysics Data System (ADS)

Larnac, Guy

2014-06-01

Main requirement on Ariane 6 are robustness, overall ownership cost and environmental impacts. To be able to meet these requirements it's mandatory to modify our usual way of working and to think the development and qualification of technologies differently. Airbus Defence and Space in the domain of materials, technologies and structures proposes a vision which address these points declined at different level:- Selection of key metallic and composite technologies to reduce drastically the cost of manufacturing,- Implementation of robust and economical way of assembly, promoting adhesive bonding and innovative technologies- Introducing virtual testing approach coupled with advanced methods and process simulation- Introduction of in-line monitoring to reduce cost of control- Implementation of the design for environment methodology with life cycle analysis to support the choice of technologies and materials- Development of EADS common materials to get benefice of aeronautic supply chain and communalitiesTo be efficient it seems evident and mandatory to develop all these approaches in an integrated and coordinated way. Advanced technologies and methodologies are supported by a strong network of collaboration enabling the integration of upstream ideas and concepts. This network is not only focused on low TRL level. Within EADS divisions intensive collaboration is deployed in order to get synergies. On the other side it's also mandatory for reliability and obsolescence issues to take care and master the supply chain.Additive layer manufacturing and thermoplastic based composite are directly concerned by this problematic. We present how, in the domain of materials and structures, aeronautic materials are considered first and how the mechanism of common qualification shared within EADS is now developed.This vision is being implemented within Airbus Defence and Space, described and reported through roadmaps. These roadmaps are the core of Airbus defence and Space strategies for the incoming years.

Low proarrhythmic potential of citalopram and escitalopram in contrast to haloperidol in an experimental whole-heart model.

PubMed

Frommeyer, Gerrit; Brücher, Benedict; von der Ahe, Henning; Kaese, Sven; Dechering, Dirk G; Kochhäuser, Simon; Bogossian, Harilaos; Milberg, Peter; Eckardt, Lars

2016-10-05

In several case reports proarrhythmic effects of citalopram and escitalopram have been reported. Systematic analyses on prorarrhythmic effects of these drugs are not yet available. The aim of the present study was to investigate if application of citalopram, escitalopram or haloperidol provokes polymorphic ventricular tachycardia in a sensitive model of proarrhythmia. In isolated rabbit hearts monophasic action potentials and ECG showed a significant QT-prolongation after application of citalopram (2µM: +47ms, 4µM: +56ms, P<0.05) accompanied by an increase of action potential duration (APD) but not dispersion of repolarization. Reduced potassium concentration in bradycardic AV-blocked hearts provoked early afterdepolarizations (EAD) in 2 of 12 hearts but no polymorphic ventricular tachycardia (pVT). Application of escitalopram also increased QT-interval (2µM: +3ms, 4µM: +30ms, P<0.05) and APD without effects on dispersion. 3 of 10 hearts showed EAD and pVT in 2 of 10 hearts (32 episodes). The results were compared to 12 rabbits treated with haloperidol which led to an increase in QT-interval (1µM:+62ms; 2µM:+96ms; P<0.01), APD and dispersion (1µM:+15ms, 2µM:+40ms; P<0.01) and induced EAD in all 12 and pVT in 10 of 12 hearts (152 episodes). Citalopram and escitalopram demonstrated a rather safe electrophysiologic profile despite significant QT prolongation. In contrast, haloperidol led to significant increase of dispersion of repolarization while this parameter remained stable under the influence of citalopram or escitalopram. These results imply that application of citalopram or escitalopram is not as proarrhythmic as some case reports might suggest while haloperidol is torsadogenic. Copyright © 2016 Elsevier B.V. All rights reserved.

Nature of adsorption on TiC(111) investigated with density-functional calculations

NASA Astrophysics Data System (ADS)

Ruberto, Carlo; Lundqvist, Bengt I.

2007-06-01

Extensive density-functional calculations are performed for chemisorption of atoms in the three first periods (H, B, C, N, O, F, Al, Si, P, S, and Cl) on the polar TiC(111) surface. Calculations are also performed for O on TiC(001), for full O(1×1) monolayer on TiC(111), as well as for bulk TiC and for the clean TiC(111) and (001) surfaces. Detailed results concerning atomic structures, energetics, and electronic structures are presented. For the bulk and the clean surfaces, previous results are confirmed. In addition, detailed results are given on the presence of C-C bonds in the bulk and at the surface, as well as on the presence of a Ti-based surface resonance (TiSR) at the Fermi level and of C-based surface resonances (CSR’s) in the lower part of the surface upper valence band. For the adsorption, adsorption energies Eads and relaxed geometries are presented, showing great variations characterized by pyramid-shaped Eads trends within each period. An extraordinarily strong chemisorption is found for the O atom, 8.8eV /adatom. On the basis of the calculated electronic structures, a concerted-coupling model for the chemisorption is proposed, in which two different types of adatom-substrate interactions work together to provide the obtained strong chemisorption: (i) adatom-TiSR and (ii) adatom-CSR’s. This model is used to successfully describe the essential features of the calculated Eads trends. The fundamental nature of this model, based on the Newns-Anderson model, should make it apt for general application to transition-metal carbides and nitrides and for predictive purposes in technological applications, such as cutting-tool multilayer coatings and MAX phases.

Methyl 2-(methylthio)benzoate: A sex attractant for the June beetles, Phyllophaga tristis and P. apicata

USDA-ARS?s Scientific Manuscript database

Male antennae of Phyllophaga tristis (Fabricius) (Coleoptera: Scarabaeidae: Melolonthinae) were tested using a coupled gas chromatograph-electroantennogram detector (GC-EAD) system for electrophysiological responses to five sex pheromones identified from other Phyllophaga species including L-valine ...

75 FR 68185 - Airworthiness Directives; EADS CASA (Type Certificate Previously Held by Construcciones...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-05

... CFR Part 39 Air transportation, Aircraft, Aviation safety, Incorporation by reference, Safety... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 39 [Docket No. FAA-2010...: Federal Aviation Administration (FAA), Department of Transportation (DOT). ACTION: Final rule. SUMMARY: We...

The 3.5-m all-SiC telescope for SPICA

NASA Astrophysics Data System (ADS)

Toulemont, Yves; Breysse, Jacques; Pierot, Dominique; Sein, Emmanuel; Nakagawa, Takao; Kaneda, Hidehiro; Onaka, Takashi; Hirabayashi, Masayuki; Narasaki, Katsuhiro; Sakuta, Hironobu; Miura, Shinji

2004-10-01

Placed on the L2 Lagrangian point, the Space Infrared Telescope for Cosmology and Astrophysics (SPICA) will operate in the 5 to 200 μm wavelength range, at 4.5K. The large aperture telescope (3.5m diameter in a single piece) requires a strong manufacturing mastering, associated with high technical performances. The background acquired by EADS-Astrium (France) on the 3.5m Silicone Carbide Herschel Telescope is a key for the success of the SPICA development. EADS-Astrium has been awarded by the Japan Aerospace Exploration Agency (JAXA) and Sumitomo Heavy Industries to assess the feasibility of the 3.5m all SiC telescope through a design phase contract. The Telescope driving requirements are the large diameter of 3.5m especially critical for the manufacturing aspects, and the Wave Front Error which has to be kept below 350nm rms over a large temperature range from ambient to the operational temperature of 4.5K which requires a strong mastering of the distortions.

Male scent-marking pheromone of Bombus ardens ardens (Hymenoptera; Apidae) attracts both conspecific queens and males

NASA Astrophysics Data System (ADS)

Kubo, Ryohei; Harano, Ken-ichi; Ono, Masato

2017-10-01

To explore the role of the volatiles emitted from male labial gland (LG) of the bumblebee Bombus ardens ardens, we investigated the responses of virgin queens and males to volatiles using a gas chromatography-electroantennographic detector (GC-EAD) system and Y-tube olfactometer. GC-EAD analysis revealed that citronellol, the main compound detected in the male LG, caused clear electrophysiological responses in the antennae of B. a. ardens virgin queens and males although two minor compounds elicited antennal responses when applied in a high concentration. Behavioral tests using a Y-tube olfactometer showed that queens and males were significantly attracted to both LG extracts and citronellol more than to the solvent alone. This is the first study to demonstrate that citronellol as a major compound of male scent-marking pheromone in B. a. ardens functions as a sex attractant for queens. The results also suggest that this compound has another function as a trail marker used by males.

NAOMI instrument: a product line of compact and versatile cameras designed for high resolution missions in Earth observation

NASA Astrophysics Data System (ADS)

Luquet, Ph.; Chikouche, A.; Benbouzid, A. B.; Arnoux, J. J.; Chinal, E.; Massol, C.; Rouchit, P.; De Zotti, S.

2017-11-01

EADS Astrium is currently developing a new product line of compact and versatile instruments for high resolution missions in Earth Observation. First version has been developed in the frame of the ALSAT-2 contract awarded by the Algerian Space Agency (ASAL) to EADS Astrium. The Silicon Carbide Korsch-type telescope coupled with a multilines detector array offers a 2.5 m GSD in PAN band at Nadir @ 680 km altitude (10 m GSD in the four multispectral bands) with a 17.5 km swath width. This compact camera - 340 (W) x 460 (L) x 510 (H) mm3, 13 kg - is embarked on a Myriade-type small platform. The electronics unit accommodates video, housekeeping, and thermal control functions and also a 64 Gbit mass memory. Two satellites are developed; the first one is planned to be launched on mid 2009. Several other versions of the instrument have already been defined with enhanced resolution or/and larger field of view.

A systems approach to the policy-level risk assessment of exotic animal diseases: network model and application to classical swine fever.

PubMed

Delgado, João; Pollard, Simon; Snary, Emma; Black, Edgar; Prpich, George; Longhurst, Phil

2013-08-01

Exotic animal diseases (EADs) are characterized by their capacity to spread global distances, causing impacts on animal health and welfare with significant economic consequences. We offer a critique of current import risk analysis approaches employed in the EAD field, focusing on their capacity to assess complex systems at a policy level. To address the shortcomings identified, we propose a novel method providing a systematic analysis of the likelihood of a disease incursion, developed by reference to the multibarrier system employed for the United Kingdom. We apply the network model to a policy-level risk assessment of classical swine fever (CSF), a notifiable animal disease caused by the CSF virus. In doing so, we document and discuss a sequence of analyses that describe system vulnerabilities and reveal the critical control points (CCPs) for intervention, reducing the likelihood of U.K. pig herds being exposed to the CSF virus. © 2012 Society for Risk Analysis.

LANDSAT-D data format control book. Volume 6, appendix G: GSFC HDT-AM inventory tape (GHIT-AM)

NASA Technical Reports Server (NTRS)

1981-01-01

The data format specifications of the Goddard HDT inventory tapes (GHITS), which accompany shipments of archival digital multispectral scanner image data (HDT-AM tapes), are defined. The GHIT is a nine-track, 1600-BPI tape which conforms to the ANSI standard and serves as an inventory and description of the image data included in the shipment. The archival MSS tapes (HDT-AMs) contain radiometrically corrected but geometrically uncorrected image data plus certain ancillary data necessary to perform the geometric corrections.

Using the Stereotype Content Model to examine group depictions in Fascism: An Archival Approach

PubMed Central

Durante, Federica; Volpato, Chiara; Fiske, Susan T.

2013-01-01

The Stereotype Content Model (SCM) suggests potentially universal intergroup depictions. If universal, they should apply across history in archival data. Bridging this gap, we examined social groups descriptions during Italy’s Fascist era. In Study 1, articles published in a Fascist magazine— La Difesa della Razza —were content analyzed, and results submitted to correspondence analysis. Admiration prejudice depicted ingroups; envious and contemptuous prejudices depicted specific outgroups, generally in line with SCM predictions. No paternalistic prejudice appeared; historical reasons might explain this finding. Results also fit the recently developed BIAS Map of behavioral consequences. In Study 2, ninety-six undergraduates rated the content-analysis traits on warmth and competence, without knowing their origin. They corroborated SCM’s interpretations of the archival data. PMID:24403646

78 FR 1866 - Extension and Redesignation of South Sudan for Temporary Protected Status

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-09

... DEPARTMENT OF HOMELAND SECURITY U.S. Citizenship and Immigration Services [CIS No. 2527-12; DHS... Protected Status AGENCY: U.S. Citizenship and Immigration Services, Department of Homeland Security. ACTION... of their Employment Authorization Documents (EADs) with U.S. Citizenship and Immigration Services...

I-95/I-395 HOV restriction study : volume 1 : summary report

DOT National Transportation Integrated Search

1999-02-01

The I-95/I-395 High Occupancy Vehicle (HOV) facility is a reversible two-lane freeway, about 27 miles long, between the southern terminus at Dumfries near Route 234 and the northern terminus between Route 27 and Eads Street in Arlington. Beyond this ...

Beta Testing of Persistent Passive Acoustic Monitors

DTIC Science & Technology

2012-10-01

three platforms provide the capability to work over a wide range of spatial and temporal scales. Hardware and software integration of the DMONs in...closely with Richard M. Ead (Sensors and Sonar Systems Department, Naval Undersea Warfare Center, NUWC Code 1535), Ted Ioannides (PS 4013) and Dave

77 FR 37790 - Airworthiness Directives; Eurocopter Deutschland GmbH Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-25

... Airworthiness Directives; Eurocopter Deutschland GmbH Helicopters AGENCY: Federal Aviation Administration (FAA... Eurocopter Deutschland GmbH (ECD) Model EC135 helicopters. The existing EAD, which was previously sent to all... new airworthiness directive (AD): 2012-11-02 Eurocopter Deutschland GmbH: Amendment 39-17065; Docket...

Description of the F-16XL Geometry and Computational Grids Used in CAWAPI

NASA Technical Reports Server (NTRS)

Boelens, O. J.; Badcock, K. J.; Gortz, S.; Morton, S.; Fritz, W.; Karman, S. L., Jr.; Michal, T.; Lamar, J. E.

2009-01-01

The objective of the Cranked-Arrow Wing Aerodynamics Project International (CAWAPI) was to allow a comprehensive validation of Computational Fluid Dynamics methods against the CAWAP flight database. A major part of this work involved the generation of high-quality computational grids. Prior to the grid generation an IGES file containing the air-tight geometry of the F-16XL aircraft was generated by a cooperation of the CAWAPI partners. Based on this geometry description both structured and unstructured grids have been generated. The baseline structured (multi-block) grid (and a family of derived grids) has been generated by the National Aerospace Laboratory NLR. Although the algorithms used by NLR had become available just before CAWAPI and thus only a limited experience with their application to such a complex configuration had been gained, a grid of good quality was generated well within four weeks. This time compared favourably with that required to produce the unstructured grids in CAWAPI. The baseline all-tetrahedral and hybrid unstructured grids has been generated at NASA Langley Research Center and the USAFA, respectively. To provide more geometrical resolution, trimmed unstructured grids have been generated at EADS-MAS, the UTSimCenter, Boeing Phantom Works and KTH/FOI. All grids generated within the framework of CAWAPI will be discussed in the article. Both results obtained on the structured grids and the unstructured grids showed a significant improvement in agreement with flight test data in comparison with those obtained on the structured multi-block grid used during CAWAP.

Performance characterization of the EarthCARE BBR Detectors

NASA Astrophysics Data System (ADS)

Proulx, C.; Allard, M.; Pope, T.; Tremblay, B.; Williamson, F.; Julien, C.; Larouche, C.; Delderfield, J.; Parker, D.

2017-11-01

The Broadband Radiometer (BBR) is an instrument being developed for the ESA EarthCARE satellite. The BBR instrument objective is to provide measurements of the reflected short-wave (0.25-4.0 μm) and emitted long-wave (4.0-50 μm) top of the atmosphere (TOA) radiance over three along-track views (forward, nadir and backward). The instrument has three fixed telescopes, one for each view, each containing a broadband detector. The BBR instrument is led by SEA in the UK with RAL responsible for the BBR optics unit (OU) while EADS Astrium is the EarthCARE prime contractor. A detailed description of the instrument is provided in [1]. The BBR detectors consist in three dedicated assemblies under the responsibility of INO. The detectors development started in 2008 and led to the design and implementation of a new gold black deposition facility at INO [2], in parallel with the preliminary and detailed design phases of the detector assemblies. As of today, two breadboard models and one engineering model have been delivered to RAL. In the BBR OU each detector mechanically interfaces with the telescope and electrically with the front-end electronics (FEE). The detectors' development is now at the Critical Design Review (CDR) level. This paper first provides a description of the detector design along with its principles of operation. It further presents and discusses measurement and analysis results for the performance characterization of the engineering model in the context of the applicable requirements. Detector-level qualification planning is finally discussed.

Radio data archiving system

NASA Astrophysics Data System (ADS)

Knapic, C.; Zanichelli, A.; Dovgan, E.; Nanni, M.; Stagni, M.; Righini, S.; Sponza, M.; Bedosti, F.; Orlati, A.; Smareglia, R.

2016-07-01

Radio Astronomical Data models are becoming very complex since the huge possible range of instrumental configurations available with the modern Radio Telescopes. What in the past was the last frontiers of data formats in terms of efficiency and flexibility is now evolving with new strategies and methodologies enabling the persistence of a very complex, hierarchical and multi-purpose information. Such an evolution of data models and data formats require new data archiving techniques in order to guarantee data preservation following the directives of Open Archival Information System and the International Virtual Observatory Alliance for data sharing and publication. Currently, various formats (FITS, MBFITS, VLBI's XML description files and ancillary files) of data acquired with the Medicina and Noto Radio Telescopes can be stored and handled by a common Radio Archive, that is planned to be released to the (inter)national community by the end of 2016. This state-of-the-art archiving system for radio astronomical data aims at delegating as much as possible to the software setting how and where the descriptors (metadata) are saved, while the users perform user-friendly queries translated by the web interface into complex interrogations on the database to retrieve data. In such a way, the Archive is ready to be Virtual Observatory compliant and as much as possible user-friendly.

A description of sexual offending committed by Canadian teachers.

PubMed

Moulden, Heather M; Firestone, Philip; Kingston, Drew A; Wexler, Audrey F

2010-07-01

The aim of this investigation was to describe teachers who sexually offend against youth and the circumstances related to these offenses. Archival Violent Crime Linkage Analysis System reports were obtained from the Royal Canadian Mounted Police, and demographic and criminal characteristics for the offender, as well as information about the victim and offense, were selected for analyses. A descriptive approach was used to analyze the qualitative reports for a group of 113 Canadian sexual offenders between 1995 and 2002. The results provide a description of adult male teachers who offended within their position of trust as well as offense and victim characteristics.

Handbook of sensor technical characteristics

NASA Astrophysics Data System (ADS)

Tanner, S.

1982-07-01

Space and terrestrial applications remote sensor systems are described. Each sensor is presented separately. Information is included on its objectives, description, technical characteristics, data products obtained, data archives location, period of operation, and measurement and potential derived parameters. Each sensor is cross indexed.

History Sources on the Internet.

ERIC Educational Resources Information Center

Fink, Kenneth D.

This paper provides descriptions of key online history resources useful to teachers, librarians, and other education professionals. Highlights include: primary sources on the Internet; archives; Online Public Access Catalogs (OPACs); the American Historical Association (AHA) Web site; state and federal government resources; business history…

Handbook of sensor technical characteristics

NASA Technical Reports Server (NTRS)

Tanner, S.

1982-01-01

Space and terrestrial applications remote sensor systems are described. Each sensor is presented separately. Information is included on its objectives, description, technical characteristics, data products obtained, data archives location, period of operation, and measurement and potential derived parameters. Each sensor is cross indexed.

75 FR 67383 - Extension of the Designation of Somalia for Temporary Protected Status

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-02

... DEPARTMENT OF HOMELAND SECURITY U.S. Citizenship and Immigration Services [CIS No. 2497-99; DHS... Status AGENCY: U.S. Citizenship and Immigration Services, Department of Homeland Security (DHS). ACTION... extension of their employment authorization documents (EADs) with U.S. Citizenship and Immigration Services...

Engineer Analysis of the Light Infantry Division (ELID). Volume 1

DTIC Science & Technology

1986-12-01

m 5. Forward logistics protection a. FARP b. Brigade petroleum, oil , and lubricant (POL) berms P P *Positlon may not be dug in if...battalion in order to complete all of the squad and equipment corabat- essencial requirements. With Che adrittion of the EAD force, there is a large

New Patterns of Collaboration and Rivalry in the US and European Defense and Aerospace Industries

DTIC Science & Technology

2009-08-19

of DaimlerChrysler Aerospace (DASA) of Germany, Aerospatiale Matra of France, and Construcciones Aeronauticas S.A. (CASA) of Spain. Its statutory...of the Cobham company of the UK) at its Bridgeport, West Virginia, plant. EADS also anticipates constructing a facility near the Sargent-Fletcher

76 FR 65995 - Airworthiness Directives; EADS CASA (Type Certificate Previously Held by Construcciones...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-25

... invite comments on the overall regulatory, economic, environmental, and energy aspects of this proposed... Customer Services (ICS), Technical Services, Avenida de Arag[oacute]n 404, 28022 Madrid, Spain; telephone... not have a significant economic impact, positive or negative, on a substantial number of small...

77 FR 64053 - Airworthiness Directives; EADS CASA (Type Certificate Previously Held by Construcciones...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-18

... regulatory, economic, environmental, and energy aspects of this proposed AD. We will consider all comments... Customer Services (ICS), Technical Services, Avenida de Arag[oacute]n 404, 28022 Madrid, Spain; telephone... not have a significant economic impact, positive or negative, on a substantial number of small...

Aerospace Materials and Process Technology Reinvestment Workshop Held in Dayton, Ohio on 18-19 May 1993.

DTIC Science & Technology

1993-05-19

The Laboratories Theory, Modeling and Simulation , • ATP Characterization J Education and Human Resources • MTC Facilities -- NBSR and CNRF MISSION...34 Automiated System for Composite Analysis (ASCA).Y -Basis for usefri(eadly numerical methods to describe composite laminates and predict ?heir response

Unmanned Surface and Underwater Vehicles

DTIC Science & Technology

2007-07-03

applications of such platforms that already exist or are discussed in literature. TNO report I TNO-DV 2006 A455 117/120 9 References [ 11 ... 11 1.1 R eading instructions... 11 2 Research on the context of different types of UVs ............................................. 13 2.1 D efi nition of U V s

Restoration of Apollo Data by the Lunar Data Project/PDS Lunar Data Node: An Update

NASA Technical Reports Server (NTRS)

Williams, David R.; Hills, H. Kent; Taylor, Patrick T.; Grayzeck, Edwin J.; Guinness, Edward A.

2016-01-01

The Apollo 11, 12, and 14 through 17 missions orbited and landed on the Moon, carrying scientific instruments that returned data from all phases of the missions, included long-lived Apollo Lunar Surface Experiments Packages (ALSEPs) deployed by the astronauts on the lunar surface. Much of these data were never archived, and some of the archived data were on media and in formats that are outmoded, or were deposited with little or no useful documentation to aid outside users. This is particularly true of the ALSEP data returned autonomously for many years after the Apollo missions ended. The purpose of the Lunar Data Project and the Planetary Data System (PDS) Lunar Data Node is to take data collections already archived at the NASA Space Science Data Coordinated Archive (NSSDCA) and prepare them for archiving through PDS, and to locate lunar data that were never archived, bring them into NSSDCA, and then archive them through PDS. Preparing these data for archiving involves reading the data from the original media, be it magnetic tape, microfilm, microfiche, or hard-copy document, converting the outmoded, often binary, formats when necessary, putting them into a standard digital form accepted by PDS, collecting the necessary ancillary data and documentation (metadata) to ensure that the data are usable and well-described, summarizing the metadata in documentation to be included in the data set, adding other information such as references, mission and instrument descriptions, contact information, and related documentation, and packaging the results in a PDS-compliant data set. The data set is then validated and reviewed by a group of external scientists as part of the PDS final archive process. We present a status report on some of the data sets that we are processing.

Ames Life Science Data Archive: Translational Rodent Research at Ames

NASA Technical Reports Server (NTRS)

Wood, Alan E.; French, Alison J.; Ngaotheppitak, Ratana; Leung, Dorothy M.; Vargas, Roxana S.; Maese, Chris; Stewart, Helen

2014-01-01

The Life Science Data Archive (LSDA) office at Ames is responsible for collecting, curating, distributing and maintaining information pertaining to animal and plant experiments conducted in low earth orbit aboard various space vehicles from 1965 to present. The LSDA will soon be archiving data and tissues samples collected on the next generation of commercial vehicles; e.g., SpaceX & Cygnus Commercial Cargo Craft. To date over 375 rodent flight experiments with translational application have been archived by the Ames LSDA office. This knowledge base of fundamental research can be used to understand mechanisms that affect higher organisms in microgravity and help define additional research whose results could lead the way to closing gaps identified by the Human Research Program (HRP). This poster will highlight Ames contribution to the existing knowledge base and how the LSDA can be a resource to help answer the questions surrounding human health in long duration space exploration. In addition, it will illustrate how this body of knowledge was utilized to further our understanding of how space flight affects the human system and the ability to develop countermeasures that negate the deleterious effects of space flight. The Ames Life Sciences Data Archive (ALSDA) includes current descriptions of over 700 experiments conducted aboard the Shuttle, International Space Station (ISS), NASA/MIR, Bion/Cosmos, Gemini, Biosatellites, Apollo, Skylab, Russian Foton, and ground bed rest studies. Research areas cover Behavior and Performance, Bone and Calcium Physiology, Cardiovascular Physiology, Cell and Molecular Biology, Chronobiology, Developmental Biology, Endocrinology, Environmental Monitoring, Gastrointestinal Physiology, Hematology, Immunology, Life Support System, Metabolism and Nutrition, Microbiology, Muscle Physiology, Neurophysiology, Pharmacology, Plant Biology, Pulmonary Physiology, Radiation Biology, Renal, Fluid and Electrolyte Physiology, and Toxicology. These experiment descriptions and data can be accessed online via the public LSDA website (http://lsda.jsc.nasa.gov) and information can be requested via the Data Request form at http://lsda.jsc.nasa.gov/common/dataRequest/dataRequest.aspx or by contacting the ALSDA Office at: Alison.J.French@nasa.gov

National Weather- RFC Development Management

Science.gov Websites

Map News Organization Search NWS ALL NOAA Go RFC Development Management Presentations Projects & ; Plans RFC Development Program RFC Archive Database Documentation Outline Workshops Contact Us resources and services. Description Graphic The RFC Development Management component of the Office of

MXA: a customizable HDF5-based data format for multi-dimensional data sets

NASA Astrophysics Data System (ADS)

Jackson, M.; Simmons, J. P.; De Graef, M.

2010-09-01

A new digital file format is proposed for the long-term archival storage of experimental data sets generated by serial sectioning instruments. The format is known as the multi-dimensional eXtensible Archive (MXA) format and is based on the public domain Hierarchical Data Format (HDF5). The MXA data model, its description by means of an eXtensible Markup Language (XML) file with associated Document Type Definition (DTD) are described in detail. The public domain MXA package is available through a dedicated web site (mxa.web.cmu.edu), along with implementation details and example data files.

Representation of viruses in the remediated PDB archive

PubMed Central

Lawson, Catherine L.; Dutta, Shuchismita; Westbrook, John D.; Henrick, Kim; Berman, Helen M.

2008-01-01

A new scheme has been devised to represent viruses and other biological assemblies with regular noncrystallographic symmetry in the Protein Data Bank (PDB). The scheme describes existing and anticipated PDB entries of this type using generalized descriptions of deposited and experimental coordinate frames, symmetry and frame transformations. A simplified notation has been adopted to express the symmetry generation of assemblies from deposited coordinates and matrix operations describing the required point, helical or crystallographic symmetry. Complete correct information for building full assemblies, subassemblies and crystal asymmetric units of all virus entries is now available in the remediated PDB archive. PMID:18645236

Detailed description of the Mayo/IBM PACS

NASA Astrophysics Data System (ADS)

Gehring, Dale G.; Persons, Kenneth R.; Rothman, Melvyn L.; Salutz, James R.; Morin, Richard L.

1991-07-01

The Mayo Clinic and IBM/Rochester have jointly developed a picture archiving system (PACS) for use with Mayo's MRI and Neuro-CT imaging modalities. The system was developed to replace the imaging system's vendor-supplied magnetic tape archiving capability. The system consists of seven MR imagers and nine CT scanners, each interfaced to the PACS via IBM Personal System/2(tm) (PS/2) computers, which act as gateways from the imaging modality to the PACS network. The PAC system operates on the token-ring component of Mayo's city-wide local area network. Also on the PACS network are four optical storage subsystems used for image archival, three optical subsystems used for image retrieval, an IBM Application System/400(tm) (AS/400) computer used for database management and multiple PS/2-based image display systems and their image servers.

SPASE 2010 - Providing Access to the Heliophysics Data Environment

NASA Astrophysics Data System (ADS)

Thieman, J. R.; King, T. A.; Roberts, D.; Spase Consortium

2010-12-01

The Heliophysics division of NASA has adopted the Space Physics Archive Search and Extract (SPASE) Data Model for use within the Heliophysics Data Environment which is composed of virtual observatories, value-added services, resident and active archives, and other data providers. The SPASE Data Model has also been adopted by Japan's Inter-university Upper atmosphere Global Observation NETwork (IUGONET), NOAA's National Geophysics Data Center (NGDC), and the Canadian Space Science Data Portal (CSSDP). Europe's HELIO project harvests information from SPASE descriptions of resources as does Planetary Plasma Interactions (PPI) Node of NASA's Planetary Data System (PDS). All of the data sets in the Heliophysics Data Environment are intended to be described by the Space Physics Archive Search and Extract (SPASE) Data Model. Many have already been described in this way. The current version of the SPASE Data Model (2.2.0) may be found on the SPASE web site at http://www.spase-group.org SPASE data set descriptions are not as difficult to create as it might seem. Help is available in both the documentation and the many tools created to support SPASE description creators. There are now a number of very experienced users who are willing to help as well. The SPASE consortium has advanced to the next step in the odyssey to achieve well coordinated federation of resource providers by designing and implementing a set of core services to facilitate the exchange of metadata and delivery of data packages. An example is the registry service shown at http://vmo.igpp.ucla.edu/registry SPASE also incorporates new technologies that are useful to the overall effort, such as cloud storage. A review of the advances, uses of the SPASE data model, and role of services in a federated environment is presented.

Dynamic Data Management Based on Archival Process Integration at the Centre for Environmental Data Archival

NASA Astrophysics Data System (ADS)

Conway, Esther; Waterfall, Alison; Pepler, Sam; Newey, Charles

2015-04-01

In this paper we decribe a business process modelling approach to the integration of exisiting archival activities. We provide a high level overview of existing practice and discuss how procedures can be extended and supported through the description of preservation state. The aim of which is to faciliate the dynamic controlled management of scientific data through its lifecycle. The main types of archival processes considered are: • Management processes that govern the operation of an archive. These management processes include archival governance (preservation state management, selection of archival candidates and strategic management) . • Operational processes that constitute the core activities of the archive which maintain the value of research assets. These operational processes are the acquisition, ingestion, deletion, generation of metadata and preservation actvities, • Supporting processes, which include planning, risk analysis and monitoring of the community/preservation environment. We then proceed by describing the feasability testing of extended risk management and planning procedures which integrate current practices. This was done through the CEDA Archival Format Audit which inspected British Atmospherics Data Centre and National Earth Observation Data Centre Archival holdings. These holdings are extensive, comprising of around 2PB of data and 137 million individual files which were analysed and characterised in terms of format based risk. We are then able to present an overview of the risk burden faced by a large scale archive attempting to maintain the usability of heterogeneous environmental data sets. We conclude by presenting a dynamic data management information model that is capable of describing the preservation state of archival holdings throughout the data lifecycle. We provide discussion of the following core model entities and their relationships: • Aspirational entities, which include Data Entity definitions and their associated Preservation Objectives. • Risk entities, which act as drivers for change within the data lifecycle. These include Acquisitional Risks, Technical Risks, Strategic Risks and External Risks • Plan entities, which detail the actions to bring about change within an archive. These include Acquisition Plans, Preservation Plans and Monitoring plans • The Result entities describe the successful outcomes of the executed plans. These include Acquisitions, Mitigations and Accepted Risks.

Catalog Descriptions Using VOTable Files

NASA Astrophysics Data System (ADS)

Thompson, R.; Levay, K.; Kimball, T.; White, R.

2008-08-01

Additional information is frequently required to describe database table contents and make it understandable to users. For this reason, the Multimission Archive at Space Telescope (MAST) creates Òdescription filesÓ for each table/catalog. After trying various XML and CSV formats, we finally chose VOTable. These files are easy to update via an HTML form, easily read using an XML parser such as (in our case) the PHP5 SimpleXML extension, and have found multiple uses in our data access/retrieval process.

Data Recovery from SCATHA Satellite

NASA Technical Reports Server (NTRS)

Fennell, J. F.; Boyd, G. M.; Redding, M. T.; McNab, M. C.

1997-01-01

This document gives a brief description of the SCATHA (P78-2) satellite and consolidates into one location information relevant to the generation of the SCATHA Summary Data parameters for the European Space Agency (ESA), under ESTEC Contract No. 11006/94/NL/CC, and the National Aeronautics and Space Administration (NASA), under Grant No. NAGW-414 1. Included are descriptions of the instruments from which the Summary Data parameters are generated, their derivation, and archival. Any questions pertaining to the Summary Data parameters should be directed to Dr. Joseph Fennell.

SAM 2 data user's guide

NASA Technical Reports Server (NTRS)

Chu, W. P.; Osborn, M. T.; Mcmaster, L. R.

1988-01-01

This document is intended to serve as a guide to the use of the data products from the Stratospheric Aerosol Measurement (SAM) 2 experiment for scientific investigations of polar stratospheric aerosols. Included is a detailed description of the Beta and Aerosol Number Density Archive Tape (BANAT), which is the SAM 2 data product containing the aerosol extinction data available for these investigations. Also included are brief descriptions of the instrument operation, data collection, processing and validation, and some of the scientific analyses conducted to date.

Academic Advising and Gender Communication

ERIC Educational Resources Information Center

Nemeth, Sean

2017-01-01

Purpose: The purpose of this correlational study was to identify whether there are differences in student satisfaction scores in academic advisement gender pairings in an undergraduate university setting. Methodology: This study was a descriptive correlational research study utilizing archival survey data. The collected data consisted of numeric…

Application of conductive polymer analysis for wood and woody plant identifications

Treesearch

A. Dan Wilson; D.G. Lester; Charisse S. Oberle

2005-01-01

An electronic aroma detection (EAD) technology known as conductive polymer analysis (CPA) was evaluated as a means of identifying and discriminating woody samples of angiosperms and gymnosperms using an analytical instrument (electronic nose) that characterizes the aroma profiles of volatiles released from excised wood into sampled headspace. The instrument measures...

77 FR 5998 - Airworthiness Directives; EADS CASA (Type Certificate Previously Held by Construcciones...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-07

...-1091; Directorate Identifier 2011-NM-037-AD; Amendment 39-16916; AD 2012-01-04] RIN 2120-AA64... contains the NPRM 2011-1091 (76 FR 65995, October 25, 2011), the regulatory evaluation, any comments.... Docket No. FAA-2011-1091; Directorate Identifier 2011-NM-037-AD. (a) Effective Date This airworthiness...

Identification of host fruit volatiles from snowberry (Symphoricarpos albus), attractive to Rhagoletis zephyria flies from Western United States

USDA-ARS?s Scientific Manuscript database

Gas chromatography coupled with electroantennogram detection (GC-EAD) was used to identify volatiles from the fruit of Snowberry, Symphoricarpos albus laevigatus, as key attractants for Rhagoletis zephyria flies reared from snowberry fruit. A nine-component blend containing 3-methylbutan-1-ol (3%), ...

Funding Education: Developing a Method of Allocation for Improvement

ERIC Educational Resources Information Center

BenDavid-Hadar, Iris

2018-01-01

Purpose: Resource allocation is a key policy instrument that affects the educational achievement distribution (EAD). The literature on methods of allocation is focused mainly on equity issues. The purpose of this paper is to develop a composite funding formula, which adds to the equity-based element (i.e. a needs-based element compensating for…

Digital Competence Model of Distance Learning Students

ERIC Educational Resources Information Center

da Silva, Ketia Kellen A.; Behar, Patricia A.

2017-01-01

This article presents the development of a digital competency model of Distance Learning (DL) students in Brazil called CompDigAl_EAD. The following topics were addressed in this study: Educational Competences, Digital Competences, and Distance Learning students. The model was developed between 2015 and 2016 and is being validated in 2017. It was…

78 FR 49235 - Airworthiness Directives; EADS CASA (Type Certificate Previously Held by Construcciones...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-13

... invite comments on the overall regulatory, economic, environmental, and energy aspects of this proposed..., 28022 Madrid, Spain; telephone +34 91 585 55 84; fax +34 91 585 55 05; email [email protected] economic impact, positive or negative, on a substantial number of small entities under the criteria of the...

Multiculturalism Is D(r)ead in Europe

ERIC Educational Resources Information Center

Bajrektarevic, Anis

2014-01-01

There is a claim currently circulating the European Union (EU), both cynical and misleading: "multiculturalism is dead in Europe". No wonder, as the conglomerate of nation-states/EU has silently handed over one of its most important debates--that of European identity--to the left and right wing parties, recently followed by several…

Implementation of a Compiler for the Functional Programming Language PHI.

DTIC Science & Technology

1987-06-01

Chapter Three. 8 his acceptance speech for the 1977 ACM Turing Award, Backus criticized traditional programming languages and programming styles. He went... Knn "mfrn ~ i ptr ->type =type; :.f (f~ead :=NULL) { -st alreaay ex-s~ tracer f head; wnile (tracer->iink - NU:LL) rdent of >-sl tracer = : racer- Iik

Identification of mosquito repellent odours from Ocimum forskolei.

PubMed

Dekker, Teun; Ignell, Rickard; Ghebru, Maedot; Glinwood, Robert; Hopkins, Richard

2011-09-22

Native mosquito repellent plants have a good potential for integrated mosquito control in local settings. Ocimum forskolei, Lamiaceae, is used in Eritrea as a spatial mosquito repellent inside houses, either through crushing fresh plants or burning dry plants. We verified whether active repellent compounds could be identified using gas-chromatography coupled electroantennogram recordings (GC-EAD) with headspace extracts of crushed plants. EAD active compounds included (R)-(-)-linalool, (S)-(+)-1-octen-3-ol, trans-caryophyllene, naphthalene, methyl salicylate, (R)-(-)-α-copaene, methyl cinnamate and (E)-ocimene. Of these compounds (R)-(-)-linalool, methyl cinnamate and methyl salicylate reduced landing of female Aedes aegypti on human skin-odor baited tubes. The latter two are novel mosquito repellent compounds. The identification of mosquito repellent compounds contributes to deciphering the mechanisms underlying repulsion, supporting the rational design of novel repellents. The three mosquito repellent compounds identified in this study are structurally dissimilar, which may indicate involvement of different sensory neurons in repulsion. Repulsion may well be enhanced through combining different repellent plants (or their synthetic mimics), and can be a locally sustainable part in mosquito control efforts.

Identification of mosquito repellent odours from Ocimum forskolei

PubMed Central

2011-01-01

Background Native mosquito repellent plants have a good potential for integrated mosquito control in local settings. Ocimum forskolei, Lamiaceae, is used in Eritrea as a spatial mosquito repellent inside houses, either through crushing fresh plants or burning dry plants. We verified whether active repellent compounds could be identified using gas-chromatography coupled electroantennogram recordings (GC-EAD) with headspace extracts of crushed plants. Results EAD active compounds included (R)-(-)-linalool, (S)-(+)-1-octen-3-ol, trans-caryophyllene, naphthalene, methyl salicylate, (R)-(-)-α-copaene, methyl cinnamate and (E)-ocimene. Of these compounds (R)-(-)-linalool, methyl cinnamate and methyl salicylate reduced landing of female Aedes aegypti on human skin-odor baited tubes. The latter two are novel mosquito repellent compounds. Conclusions The identification of mosquito repellent compounds contributes to deciphering the mechanisms underlying repulsion, supporting the rational design of novel repellents. The three mosquito repellent compounds identified in this study are structurally dissimilar, which may indicate involvement of different sensory neurons in repulsion. Repulsion may well be enhanced through combining different repellent plants (or their synthetic mimics), and can be a locally sustainable part in mosquito control efforts. PMID:21936953

Using Network Analysis to Characterize Biogeographic Data in a Community Archive

NASA Astrophysics Data System (ADS)

Wellman, T. P.; Bristol, S.

2017-12-01

Informative measures are needed to evaluate and compare data from multiple providers in a community-driven data archive. This study explores insights from network theory and other descriptive and inferential statistics to examine data content and application across an assemblage of publically available biogeographic data sets. The data are archived in ScienceBase, a collaborative catalog of scientific data supported by the U.S Geological Survey to enhance scientific inquiry and acuity. In gaining understanding through this investigation and other scientific venues our goal is to improve scientific insight and data use across a spectrum of scientific applications. Network analysis is a tool to reveal patterns of non-trivial topological features in the data that do not exhibit complete regularity or randomness. In this work, network analyses are used to explore shared events and dependencies between measures of data content and application derived from metadata and catalog information and measures relevant to biogeographic study. Descriptive statistical tools are used to explore relations between network analysis properties, while inferential statistics are used to evaluate the degree of confidence in these assessments. Network analyses have been used successfully in related fields to examine social awareness of scientific issues, taxonomic structures of biological organisms, and ecosystem resilience to environmental change. Use of network analysis also shows promising potential to identify relationships in biogeographic data that inform programmatic goals and scientific interests.

Flight Validation of the Thermal Propellant Gauging Method used at EADS Astrium

NASA Astrophysics Data System (ADS)

Dandaleix, L.; Ounougha, L.; Jallade, S.

2004-10-01

EADS Astrium recently met a major milestone in the field of propellant gauging with the first reorbitation of an Eurostar tanks equipped satellite. It proved successful determining the remaining available propellant mass for spacecraft displacement beyond the customer specified graveyard orbit; thus demonstrating its expertness in Propellant Gauging in correlation with tank residual mass minimization. A critical parameter in satellite operational planning is indeed the accurate knowledge of the on-board remaining propellant mass; basically for the commercial telecommunication missions, where it is the major criterion for lifetime maximization. To provide an accurate and reliable process for measurement of this propellant mass throughout lifetime, EADS Astrium uses a Combination of two independent techniques: The Dead Reckoning Method (maximum accuracy at BOL), based on thrusters flow rate prediction &the Thermal Propellant Gauging Technique, deriving the propellant mass from the tank thermal capacity (Absolute gauging method, with increasing accuracy along lifetime). Then, the present article shows the recent flight validation of the Gauging method obtained for Eurostar E2000 propellant tanks including the validation of the different thermodynamic models. ABBREVIATIONS &ACRONYMS BOL, MOL, EOL: Beginning, Middle &End of Life Cempty: Empty tank thermal inertia [J/K] Chelium: Helium thermal inertia [J/K] Cpropellant: Propellant thermal inertia [J/K] Ct = C1+C2: Total tank thermal inertia (Subscript for upper node and for lower node) [J/K] CPS: Combined Propulsion System DR: Dead Reckoning FM: Flight Model LAE: Liquid Apogee Engine lsb: Least significant byte M0: TPGS Uncertainty component linked to Cempty mox, mfuel: Propellant mass of oxidiser &fuel [kg] Pox, Pfuel: Pressure of oxidiser &fuel [bar] PTA: Propellant Tank Assembly Q: Heater power [W] Qox, Qfuel: Mass flow rate of oxidiser &fuel [kg/s] RCT: Reaction Control Thrusters T0: Spacecraft platform equilibrium temperature TPGS: Thermal Propellant Gauging Software TPGT: Thermal Propellant Gauging Technique T1i: Internal thermal gradients [K] T2i: External thermal gradients [K] Ï 1: Internal thermal characteristic time [s] 2: External thermal characteristic time [s

Effects of interleukin-8 on estradiol and progesterone production by bovine granulosa cells from large follicles and progesterone production by luteinizing granulosa cells in culture.

PubMed

Shimizu, Takashi; Kaji, Ayami; Murayama, Chiaki; Magata, Fumie; Shirasuna, Koumei; Wakamiya, Kaori; Okuda, Kiyoshi; Miyamoto, Akio

2012-01-01

Interleukin 8 (IL-8) is a chemoattractant involved in the recruitment and activation of neutrophils and is associated with the ovulate process. We examined the possible role of IL-8 in steroid production by bovine granulosa cells before and after ovulation. The concentration of IL-8 in the follicular fluid of estrogen-active dominant (EAD) and pre-ovulatory follicles (POF) was higher than that of small follicles (SF). CXCR1 mRNA expression was higher in the granulosa cells of EAD and POF than that of SF. In contrast, CXCR2 mRNA expression was lower in granulosa cells of EAD and POF than in SF. IL-8 inhibited estradiol (E2) production in follicle-stimulating hormone (FSH)-treated granulosa cells at 48 h of culture. IL-8 also suppressed CYP19A1 mRNA expression in FSH-treated granulosa cells. IL-8 stimulated progesterone (P4) production in luteinizing hormone (LH)-treated granulosa cells at 48 h of culture. Although IL-8 did not alter the expression of genes associated with P4 production, it induced StAR protein expression in LH-treated granulosa cells. The expression of CXCR1 mRNA in corpus luteum (CL) did not change during the luteal phase. In contrast, the expression of CXCR2 mRNA in middle CL was significantly higher than in early and regression CL during the luteal phase. In luteinizing granulosa cells, an in vitro model of granulosa cell luteinization, CXCR2 mRNA expression was downregulated, whereas CXCR1 mRNA expression was unchanged. IL-8 also stimulated P4 production in luteinizing granulosa cells. These data provide evidence that IL-8 functions not only as a chemokine, but also act as a regulator of steroid synthesis in granulosa cells to promote luteinization after ovulation. Copyright © 2011 Elsevier Ltd. All rights reserved.

Viking Seismometer PDS Archive Dataset

NASA Astrophysics Data System (ADS)

Lorenz, R. D.

2016-12-01

The Viking Lander 2 seismometer operated successfully for over 500 Sols on the Martian surface, recording at least one likely candidate Marsquake. The Viking mission, in an era when data handling hardware (both on board and on the ground) was limited in capability, predated modern planetary data archiving, and ad-hoc repositories of the data, and the very low-level record at NSSDC, were neither convenient to process nor well-known. In an effort supported by the NASA Mars Data Analysis Program, we have converted the bulk of the Viking dataset (namely the 49,000 and 270,000 records made in High- and Event- modes at 20 and 1 Hz respectively) into a simple ASCII table format. Additionally, since wind-generated lander motion is a major component of the signal, contemporaneous meteorological data are included in summary records to facilitate correlation. These datasets are being archived at the PDS Geosciences Node. In addition to brief instrument and dataset descriptions, the archive includes code snippets in the freely-available language 'R' to demonstrate plotting and analysis. Further, we present examples of lander-generated noise, associated with the sampler arm, instrument dumps and other mechanical operations.

Effects of early afterdepolarizations on excitation patterns in an accurate model of the human ventricles

PubMed Central

Seemann, Gunnar; Panfilov, Alexander V.; Vandersickel, Nele

2017-01-01

Early Afterdepolarizations, EADs, are defined as the reversal of the action potential before completion of the repolarization phase, which can result in ectopic beats. However, the series of mechanisms of EADs leading to these ectopic beats and related cardiac arrhythmias are not well understood. Therefore, we aimed to investigate the influence of this single cell behavior on the whole heart level. For this study we used a modified version of the Ten Tusscher-Panfilov model of human ventricular cells (TP06) which we implemented in a 3D ventricle model including realistic fiber orientations. To increase the likelihood of EAD formation at the single cell level, we reduced the repolarization reserve (RR) by reducing the rapid delayed rectifier Potassium current and raising the L-type Calcium current. Varying these parameters defined a 2D parametric space where different excitation patterns could be classified. Depending on the initial conditions, by either exciting the ventricles with a spiral formation or burst pacing protocol, we found multiple different spatio-temporal excitation patterns. The spiral formation protocol resulted in the categorization of a stable spiral (S), a meandering spiral (MS), a spiral break-up regime (SB), spiral fibrillation type B (B), spiral fibrillation type A (A) and an oscillatory excitation type (O). The last three patterns are a 3D generalization of previously found patterns in 2D. First, the spiral fibrillation type B showed waves determined by a chaotic bi-excitable regime, i.e. mediated by both Sodium and Calcium waves at the same time and in same tissue settings. In the parameter region governed by the B pattern, single cells were able to repolarize completely and different (spiral) waves chaotically burst into each other without finishing a 360 degree rotation. Second, spiral fibrillation type A patterns consisted of multiple small rotating spirals. Single cells failed to repolarize to the resting membrane potential hence prohibiting the Sodium channel gates to recover. Accordingly, we found that Calcium waves mediated these patterns. Third, a further reduction of the RR resulted in a more exotic parameter regime whereby the individual cells behaved independently as oscillators. The patterns arose due to a phase-shift of different oscillators as disconnection of the cells resulted in continuation of the patterns. For all patterns, we computed realistic 9 lead ECGs by including a torso model. The B and A type pattern exposed the behavior of Ventricular Tachycardia (VT). We conclude that EADs at the single cell level can result in different types of cardiac fibrillation at the tissue and 3D ventricle level. PMID:29216239

A basis for a visual language for describing, archiving and analyzing functional models of complex biological systems

PubMed Central

Cook, Daniel L; Farley, Joel F; Tapscott, Stephen J

2001-01-01

Background: We propose that a computerized, internet-based graphical description language for systems biology will be essential for describing, archiving and analyzing complex problems of biological function in health and disease. Results: We outline here a conceptual basis for designing such a language and describe BioD, a prototype language that we have used to explore the utility and feasibility of this approach to functional biology. Using example models, we demonstrate that a rather limited lexicon of icons and arrows suffices to describe complex cell-biological systems as discrete models that can be posted and linked on the internet. Conclusions: Given available computer and internet technology, BioD may be implemented as an extensible, multidisciplinary language that can be used to archive functional systems knowledge and be extended to support both qualitative and quantitative functional analysis. PMID:11305940

Automated search and retrieval of information from imaged documents using optical correlation techniques

NASA Astrophysics Data System (ADS)

Stalcup, Bruce W.; Dennis, Phillip W.; Dydyk, Robert B.

1999-10-01

Litton PRC and Litton Data Systems Division are developing a system, the Imaged Document Optical Correlation and Conversion System (IDOCCS), to provide a total solution to the problem of managing and retrieving textual and graphic information from imaged document archives. At the heart of IDOCCS, optical correlation technology provides the search and retrieval of information from imaged documents. IDOCCS can be used to rapidly search for key words or phrases within the imaged document archives. In addition, IDOCCS can automatically compare an input document with the archived database to determine if it is a duplicate, thereby reducing the overall resources required to maintain and access the document database. Embedded graphics on imaged pages can also be exploited; e.g., imaged documents containing an agency's seal or logo can be singled out. In this paper, we present a description of IDOCCS as well as preliminary performance results and theoretical projections.

The MAO NASU Plate Archive Database. Current Status and Perspectives

NASA Astrophysics Data System (ADS)

Pakuliak, L. K.; Sergeeva, T. P.

2006-04-01

The preliminary online version of the database of the MAO NASU plate archive is constructed on the basis of the relational database management system MySQL and permits an easy supplement of database with new collections of astronegatives, provides a high flexibility in constructing SQL-queries for data search optimization, PHP Basic Authorization protected access to administrative interface and wide range of search parameters. The current status of the database will be reported and the brief description of the search engine and means of the database integrity support will be given. Methods and means of the data verification and tasks for the further development will be discussed.

Two Models for Implementing Senior Mentor Programs in Academic Medical Settings

ERIC Educational Resources Information Center

Corwin, Sara J.; Bates, Tovah; Cohan, Mary; Bragg, Dawn S.; Roberts, Ellen

2007-01-01

This paper compares two models of undergraduate geriatric medical education utilizing senior mentoring programs. Descriptive, comparative multiple-case study was employed analyzing program documents, archival records, and focus group data. Themes were compared for similarities and differences between the two program models. Findings indicate that…

Developing Data Resources for the 21st Century : New Uses for Archived Intelligent Transportation Systems (ITS) Transit Data

DOT National Transportation Integrated Search

2003-08-01

This report is broken into four sections. Section 1 provides a very brief description of transit in early American cities, describes the second generation of transit and the role of government planning and concludes with the third generation of trans...

Re-Imagining Archival Display: Creating User-Friendly Finding Aids

ERIC Educational Resources Information Center

Daines, J. Gordon, III; Nimer, Cory L.

2011-01-01

This article examines how finding aids are structured and delivered, considering alternative approaches. It suggests that single-level displays, those that present a single component of a multilevel description to users at a time, have the potential to transform the delivery and display of collection information while improving the user…

Gulf Coast Ecosystem Restoration Task Force Meeting and Public Listening

Science.gov Websites

Data Media & News Publications Press Releases Story Archive Home Gulf Coast Ecosystem Restoration Task Force Meeting and Public Listening Session Gulf Coast Ecosystem Restoration Task Force Meeting and Title: Gulf Coast Ecosystem Restoration Task Force Meeting and Public Listening SessionDescription: The

Documentation and Development. Experience in Algeria

ERIC Educational Resources Information Center

Tchuigoua, J. Founou

1972-01-01

A description of the activities of the Documentation, Library and Archives Department of the Algiers Chamber of Commerce and Industry, which is run by a small staff on a modest budget, provides documentation services for the staff of the Chamber of Commerce and also assists other centers in Algeria. (Author)

Mistreatment in Assisted Living Facilities: Complaints, Substantiations, and Risk Factors

ERIC Educational Resources Information Center

Phillips, Linda R.; Guo, Guifang

2011-01-01

Purpose of the Study: Use archived public data from Arizona to explore relationships among selected institutional and resident risk and situation-specific factors and complaints and substantiated allegations of various types of mistreatment in assisted living facilities (ALFs). Design and Methods: An exploratory/descriptive 2-group design was…

Digitized Special Collections and Multiple User Groups

ERIC Educational Resources Information Center

Gueguen, Gretchen

2010-01-01

Many organizations have evolved since their early attempts to mount digital exhibits on the Web and are experimenting with ways to increase the scale of their digitized collections by utilizing archival finding aid description rather than resource-intensive collections and exhibits. This article examines usability research to predict how such…

78 FR 68688 - Airworthiness Directives; EADS CASA (Type Certificate Previously Held by Construcciones...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-15

... fuel transfer system. We are issuing this AD to detect and correct damage to certain fuel booster pumps... problem with the fuel transfer system. The results of the subsequent investigation revealed damage on the... was prompted by a report of an in-flight problem with the fuel transfer system. We are issuing this AD...

Evaluate, Analyze, Describe (EAD): Confronting Underlying Issues of Racism and Other Prejudices for Effective Intercultural Communication

ERIC Educational Resources Information Center

Velasco, Daniel

2015-01-01

Racism and other prejudices have hindered efforts to diversify and further many fields, including education, psychology, politics, law, and healthcare (Race for Opportunity, 2010). Although there are many ways to combat these prejudices, intercultural communication continues to be a vital component in assisting individuals and groups with valuing…

78 FR 73742 - Airworthiness Directives; EADS CASA (Type Certificate Previously Held by Construcciones...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-09

... received by the closing date and may amend this proposed AD based on those comments. We will post all... provide. We will also post a report summarizing each substantive verbal contact we receive about this... for operation in the United States. Pursuant to our bilateral agreement with the State of Design...

Synthetic studies toward 7-epi-sesquithujene, bicyclic sesquiterpene antennally active to emerald ash borer

USDA-ARS?s Scientific Manuscript database

Emerald ash borer, Agrilus planipennis, is an invasive beetle that has been causing extensive mortality of ash trees since arriving in North America in 2002. 7-epi-Sesquithujene (1) is produced by stressed ash and elicits a strong EAD response on the emerald ash borer antennae. In the course of ma...

The NATO STO Task Group AVT-201 on Extended Assessment of Stability and Control Prediction Methods for NATO Air Vehicles

DTIC Science & Technology

2014-06-20

concentrated on SACCON. The planform and section profiles were defined in cooperation between DLR and EADS -MAS during the early stages of AVT-161. DLR...however most predictions were made as first-order temporal predictions. Given the highly unsteady flow fields observed by the experiments, unsteady

75 FR 37339 - Airworthiness Directives; EADS CASA (Type Certificate Previously Held by Construcciones...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-29

..., Avenida de Arag[oacute]n 404, 28022 Madrid, Spain; telephone +34 91 585 55 84; fax +34 91 585 55 05; e... the beginning of your comments. We specifically invite comments on the overall regulatory, economic, environmental, and energy aspects of this proposed AD. We will consider all comments received by the closing...

ESDORA: A Data Archive Infrastructure Using Digital Object Model and Open Source Frameworks

NASA Astrophysics Data System (ADS)

Shrestha, Biva; Pan, Jerry; Green, Jim; Palanisamy, Giriprakash; Wei, Yaxing; Lenhardt, W.; Cook, R. Bob; Wilson, B. E.; Leggott, M.

2011-12-01

There are an array of challenges associated with preserving, managing, and using contemporary scientific data. Large volume, multiple formats and data services, and the lack of a coherent mechanism for metadata/data management are some of the common issues across data centers. It is often difficult to preserve the data history and lineage information, along with other descriptive metadata, hindering the true science value for the archived data products. In this project, we use digital object abstraction architecture as the information/knowledge framework to address these challenges. We have used the following open-source frameworks: Fedora-Commons Repository, Drupal Content Management System, Islandora (Drupal Module) and Apache Solr Search Engine. The system is an active archive infrastructure for Earth Science data resources, which include ingestion, archiving, distribution, and discovery functionalities. We use an ingestion workflow to ingest the data and metadata, where many different aspects of data descriptions (including structured and non-structured metadata) are reviewed. The data and metadata are published after reviewing multiple times. They are staged during the reviewing phase. Each digital object is encoded in XML for long-term preservation of the content and relations among the digital items. The software architecture provides a flexible, modularized framework for adding pluggable user-oriented functionality. Solr is used to enable word search as well as faceted search. A home grown spatial search module is plugged in to allow user to make a spatial selection in a map view. A RDF semantic store within the Fedora-Commons Repository is used for storing information on data lineage, dissemination services, and text-based metadata. We use the semantic notion "isViewerFor" to register internally or externally referenced URLs, which are rendered within the same web browser when possible. With appropriate mapping of content into digital objects, many different data descriptions, including structured metadata, data history, auditing trails, are captured and coupled with the data content. The semantic store provides a foundation for possible further utilizations, including provide full-fledged Earth Science ontology for data interpretation or lineage tracking. Datasets from the NASA-sponsored Oak Ridge National Laboratory Distributed Active Archive Center (ORNL DAAC) as well as from the Synthesis Thematic Data Center (MAST-DC) are used in a testing deployment with the system. The testing deployment allows us to validate the features and values described here for the integrated system, which will be presented here. Overall, we believe that the integrated system is valid, reusable data archive software that provides digital stewardship for Earth Sciences data content, now and in the future. References: [1] Devarakonda, Ranjeet, and Harold Shanafield. "Drupal: Collaborative framework for science research." Collaboration Technologies and Systems (CTS), 2011 International Conference on. IEEE, 2011. [2] Devarakonda, Ranjeet, et al. "Semantic search integration to climate data." Collaboration Technologies and Systems (CTS), 2014 International Conference on. IEEE, 2014.

Hgis and Archive Researches: a Tool for the Study of the Ancient Mill Channel of Cesena (italy)

NASA Astrophysics Data System (ADS)

Bitelli, G.; Bartolini, F.; Gatta, G.

2016-06-01

The present study aims to demonstrate the usefulness of GIS to support archive searches and historical studies (e.g. related to industrial archaeology), in the case of an ancient channel for mill powering near Cesena (Emilia-Romagna, Italy), whose history is weaved together with the history of the Compagnia dei Molini di Cesena mill company, the most ancient limited company in Italy. Several historical maps (about 40 sheets in total) inherent the studied area and 80 archive documents (drawings, photos, specifications, administrative acts, newspaper articles), over a period of more than 600 years, were collected. Once digitized, historical maps were analysed, georeferenced and mosaicked where necessary. Subsequently, in all the maps the channel with its four mills and the Savio river were vectorized. All the additional archive documents were digitized, catalogued and stored. Using the QGIS open source platform, a Historical GIS was created, encompassing the current cartographic base and all historical maps, with their vectorized elements; each archive document was linked to the proper historical map, so that the document can be immediately retrieved and visualized. In such a HGIS, the maps form the base for a spatial and temporal navigation, facilitated by a specific interface; the external documents linked to them complete the description of the represented elements. This simple and interactive tool offers a new approach to archive searches, as it allows reconstruction in space and time of the evolution of the ancient channel and the history of this important mill company.

Beginning with the Particular: Reimagining Professional Development as a Feminist Practice

ERIC Educational Resources Information Center

Schultz, Katherine

2011-01-01

This article analyzes the work of a long-term network of teachers, the Philadelphia Teachers Learning Cooperative, with a focus on their descriptive practices. Drawing on three years of ethnographic documentation of weekly meetings and a historical archive of meetings over 30 years, I characterize the teachers' knowledge about teaching and…

A Description of Sexual Offending Committed by Canadian Teachers

ERIC Educational Resources Information Center

Moulden, Heather M.; Firestone, Philip; Kingston, Drew A.; Wexler, Audrey F.

2010-01-01

The aim of this investigation was to describe teachers who sexually offend against youth and the circumstances related to these offenses. Archival Violent Crime Linkage Analysis System reports were obtained from the Royal Canadian Mounted Police, and demographic and criminal characteristics for the offender, as well as information about the victim…

Louisiana Public Scoping Meeting | NOAA Gulf Spill Restoration

Science.gov Websites

Archive Home Louisiana Public Scoping Meeting Louisiana Public Scoping Meeting share Posted on February 28 , 2011 | Assessment and Early Restoration Restoration Area Title: Louisiana Public Scoping Meeting Location: Belle Chasse, LA Start Time: 18:30 Description: As part of the public scoping process, the co

"The BFG" and the Spaghetti Book Club: A Case Study of Children as Critics

ERIC Educational Resources Information Center

Hoffman, A. Robin

2010-01-01

Situated at the intersections of ethnography, childhood studies, literary studies, and education research, this reception study seeks to access real children's responses to a particular text, and to offer empirical description of actual reading experiences. Survey data is generated by taking advantage of an online resource: an archive of…

Underachievement in Primary Grade Students: A Review of Kindergarten Enrollment and DIBELS Scores

ERIC Educational Resources Information Center

Rice, Shawnik Marie

2013-01-01

Student underachievement in kindergarten through Grade 3 continues to be a challenge in the Philadelphia School District. The purpose of this quantitative descriptive correlation study was to examine, using record archives from one Philadelphia school, whether there is a relationship between (a) reading achievement scores for the Dynamic…

Sentence-Based Metadata: An Approach and Tool for Viewing Database Designs.

ERIC Educational Resources Information Center

Boyle, John M.; Gunge, Jakob; Bryden, John; Librowski, Kaz; Hanna, Hsin-Yi

2002-01-01

Describes MARS (Museum Archive Retrieval System), a research tool which enables organizations to exchange digital images and documents by means of a common thesaurus structure, and merge the descriptive data and metadata of their collections. Highlights include theoretical basis; searching the MARS database; and examples in European museums.…

Man-computer Inactive Data Access System (McIDAS). [design, development, fabrication, and testing

NASA Technical Reports Server (NTRS)

1973-01-01

A technical description is given of the effort to design, develop, fabricate, and test the two dimensional data processing system, McIDAS. The system has three basic sections: an access and data archive section, a control section, and a display section. Areas reported include hardware, system software, and applications software.

NUWUVI: A Southern Paiute History.

ERIC Educational Resources Information Center

Inter-Tribal Council of Nevada, Reno.

The first in a series of four histories of native Nevadans, this volume presents the story of the Southern Paiutes, or Nuwuvi. Based on interviews with tribal members and research conducted at numerous archives and record centers, the history begins with a description of the ancient culture and territory of the many Nuwuvi bands that lived,…

Building Community Around Hydrologic Data Models Within CUAHSI

NASA Astrophysics Data System (ADS)

Maidment, D.

2007-12-01

The Consortium of Universities for the Advancement of Hydrologic Science, Inc (CUAHSI) has a Hydrologic Information Systems project which aims to provide better data access and capacity for data synthesis for the nation's water information, both that collected by academic investigators and that collected by water agencies. These data include observations of streamflow, water quality, groundwater levels, weather and climate and aquatic biology. Each water agency or research investigator has a unique method of formatting their data (syntactic heterogeneity) and describing their variables (semantic heterogeneity). The result is a large agglomeration of data in many formats and descriptions whose full content is hard to interpret and analyze. CUAHSI is helping to resolve syntactic heterogeneity through the development of WaterML, a standard XML markup language for communicating water observations data through web services, and a standard relational database structure for archiving data called the Observations Data Model. Variables in these data archiving and communicating systems are indexed against a controlled vocabulary of descriptive terms to provide the capacity to synthesize common data types from disparate data sources.

Integrated Nuclear and Conventional Theater Warfare Simulation (INWARS) Documentation. Part IV. User’s Manual Component. Volume III. EAD C2I Inputs.

DTIC Science & Technology

1980-02-08

hours 0 Input Format: Integer b. Creatina Rescource Allocation Blocks The creation of a specific resource allocation block as a directive component is...is directed. 0 Range: N/A . Input Format: INT/NUC/CHM b. Creatina Employment Packages An employment package block has the structure portrayed in Figure

Southern pine beetle, Dendroctonus frontalis, antennal and behavioral responses to nonhost leaf and bark volatiles

Treesearch

William Shepherd; Brian Sullivan

2013-01-01

A growing body of evidence suggests that bark beetles detect and avoid release points of volatile compounds associated with nonhost species, and thus such nonhost volatiles may have potential utility in the management of bark beetles. We used a coupled gas chromatograph-electroantennographic detector (GC-EAD) to assay the olfactory sensitivity of the southern pine...

From to : Nicknames, Play and Identity on Internet Relay Chat.

ERIC Educational Resources Information Center

Bechar-Israeli, Haya

1995-01-01

Examines nicknames of Internet Relay Chat (IRC) users, whose identities are condensed into a single line which states their nicknames, the electronic address, and a slogan or the users' real names. Demonstrates that although people play games with their nicknames, the nicknames they choose are an inherent part of their Net identity and their…

EAD in the Department of Special Collections and Western Manuscripts at the Bodleian Library, United Kingdom

ERIC Educational Resources Information Center

Webb, Mike

2005-01-01

The strategy for conversion to electronic cataloguing of western manuscripts in the Bodleian Library has been to a large extent determined by circumstances--the size and variety of the manuscript collections, the existence of detailed published catalogues for the earlier collections, the availability of funds for specific purposes, and, above all,…

Fibre optics in the SMOS mission

NASA Astrophysics Data System (ADS)

Kudielka, K.; Benito-Hernández, F. J.; Rits, W.; Martin-Neira, M.

2017-11-01

Launched on November 2nd, 2009, SMOS (Soil Moisture, Ocean Salinity) is the second Earth Explorer Opportunity mission developed as part of ESA's Living Planet Programme. It demonstrates a completely new type of instrument - a large, deployable synthetic-aperture microwave radiometer [1]. RUAG Space, Switzerland, as a subcontractor of EADS Astrium, Spain, has provided the instrument's fibreoptic harness, which interconnects the central data processor with all 69 microwave receivers, as well as 12 auxiliary units on board. For reasons explained in Section 3, SMOS is the first European mission extensively using both fibre-optic clock distribution and data transmission in space. In Section 2, we present an overview of the scientific goals of SMOS, and describe the payload's basic function. There from we derive the rationale and the design of the fibre-optic harness (Section 3). In Section 4 all development, manufacturing, and test activities are summarised, which culminated in the successful delivery of all flight units to EADS Astrium by October 2006. We present the major test results obtained with the flight harness (Section 5), and conclude with a short summary of the higher-level activities, which lead to successful launch and commissioning of the SMOS satellite (Section 6).

Structure, dynamics and movement patterns of the Australian pig industry.

PubMed

East, I J; Davis, J; Sergeant, E S G; Garner, M G

2014-03-01

To assess management practices and movement patterns that could influence the establishment and spread of exotic animal diseases (EAD) in pigs in Australia. A literature review of published information and a telephone survey of 370 pig producers owning >10 pigs who were registered with the PigPass national vendor declaration scheme. The movement and marketing patterns of Australian pig producers interviewed were divided into two groups based predominantly on the size of the herd. Major pig producers maintain closed herds, use artificial insemination and market direct to abattoirs. Smaller producers continue to purchase from saleyards and market to other farms, abattoirs and through saleyards in an apparently opportunistic fashion. The role of saleyards in the Australian pig industry continues to decline, with 92% of all pigs marketed directly from farm to abattoir. This survey described movement patterns that will assist in modelling the potential spread of EAD in the Australian pig industry. Continued movement towards vertical integration and closed herds in the Australian pig industry effectively divides the industry into a number of compartments that mitigate against the widespread dissemination of disease to farms adopting these practices. © 2014 Australian Veterinary Association.

Phase-Shifted Eccentric Core Fiber Bragg Grating Fabricated by Electric Arc Discharge for Directional Bending Measurement.

PubMed

Ouyang, Yang; Liu, Jianxia; Xu, Xiaofeng; Zhao, Yujia; Zhou, Ai

2018-04-11

A phase-shifted eccentric core fiber Bragg grating (PS-ECFBG) fabricated by electric arc discharge (EAD) is presented and demonstrated. It is composed of a fraction of eccentric core fiber fusion spliced in between two pieces of commercial single mode fibers, where a PS-FBG was written. The EAD in this work could flexibly change the amount of phase-shift by changing the discharge number or discharge duration. Because of the offset location of the eccentric core and the ultra-narrow resonant peak of the PS-ECFBG, it has a higher accuracy for measuring the directional bend. The elongation and compression of the eccentric core keep the magnitude of phase shift still unchanged during the bending process. The bending sensitivities of the PS-ECFBG at two opposite most sensitive directions are 57.4 pm/m -1 and -51.5 pm/m -1 , respectively. Besides, the PS-ECFBG has the potential to be a tunable narrow bandpass filter, which has a wider bi-directional adjustable range because of the bending responses. The strain and temperature sensitivities of the PS-ECFBG are experimentally measured as well, which are 0.70 pm/με and 8.85 pm/°C, respectively.

EBI metagenomics--a new resource for the analysis and archiving of metagenomic data.

PubMed

Hunter, Sarah; Corbett, Matthew; Denise, Hubert; Fraser, Matthew; Gonzalez-Beltran, Alejandra; Hunter, Christopher; Jones, Philip; Leinonen, Rasko; McAnulla, Craig; Maguire, Eamonn; Maslen, John; Mitchell, Alex; Nuka, Gift; Oisel, Arnaud; Pesseat, Sebastien; Radhakrishnan, Rajesh; Rocca-Serra, Philippe; Scheremetjew, Maxim; Sterk, Peter; Vaughan, Daniel; Cochrane, Guy; Field, Dawn; Sansone, Susanna-Assunta

2014-01-01

Metagenomics is a relatively recently established but rapidly expanding field that uses high-throughput next-generation sequencing technologies to characterize the microbial communities inhabiting different ecosystems (including oceans, lakes, soil, tundra, plants and body sites). Metagenomics brings with it a number of challenges, including the management, analysis, storage and sharing of data. In response to these challenges, we have developed a new metagenomics resource (http://www.ebi.ac.uk/metagenomics/) that allows users to easily submit raw nucleotide reads for functional and taxonomic analysis by a state-of-the-art pipeline, and have them automatically stored (together with descriptive, standards-compliant metadata) in the European Nucleotide Archive.

EOS MLS Science Data Processing System: A Description of Architecture and Capabilities

NASA Technical Reports Server (NTRS)

Cuddy, David T.; Echeverri, Mark D.; Wagner, Paul A.; Hanzel, Audrey T.; Fuller, Ryan A.

2006-01-01

This paper describes the architecture and capabilities of the Science Data Processing System (SDPS) for the EOS MLS. The SDPS consists of two major components--the Science Computing Facility and the Science Investigator-led Processing System. The Science Computing Facility provides the facilities for the EOS MLS Science Team to perform the functions of scientific algorithm development, processing software development, quality control of data products, and scientific analyses. The Science Investigator-led Processing System processes and reprocesses the science data for the entire mission and delivers the data products to the Science Computing Facility and to the Goddard Space Flight Center Earth Science Distributed Active Archive Center, which archives and distributes the standard science products.

EBI metagenomics—a new resource for the analysis and archiving of metagenomic data

PubMed Central

Hunter, Sarah; Corbett, Matthew; Denise, Hubert; Fraser, Matthew; Gonzalez-Beltran, Alejandra; Hunter, Christopher; Jones, Philip; Leinonen, Rasko; McAnulla, Craig; Maguire, Eamonn; Maslen, John; Mitchell, Alex; Nuka, Gift; Oisel, Arnaud; Pesseat, Sebastien; Radhakrishnan, Rajesh; Rocca-Serra, Philippe; Scheremetjew, Maxim; Sterk, Peter; Vaughan, Daniel; Cochrane, Guy; Field, Dawn; Sansone, Susanna-Assunta

2014-01-01

Metagenomics is a relatively recently established but rapidly expanding field that uses high-throughput next-generation sequencing technologies to characterize the microbial communities inhabiting different ecosystems (including oceans, lakes, soil, tundra, plants and body sites). Metagenomics brings with it a number of challenges, including the management, analysis, storage and sharing of data. In response to these challenges, we have developed a new metagenomics resource (http://www.ebi.ac.uk/metagenomics/) that allows users to easily submit raw nucleotide reads for functional and taxonomic analysis by a state-of-the-art pipeline, and have them automatically stored (together with descriptive, standards-compliant metadata) in the European Nucleotide Archive. PMID:24165880

Archive of sediment data from vibracores collected in 2010 offshore of the Mississippi barrier islands

USGS Publications Warehouse

Kelso, Kyle W.; Flocks, James G.

2015-01-01

Selection of the core site locations was based on geophysical surveys conducted around the islands from 2008 to 2010. The surveys, using acoustic systems to image and interpret the nearsurface stratigraphy, were conducted to investigate the geologic controls on island evolution. This data series serves as an archive of sediment data collected from August to September 2010, offshore of the Mississippi barrier islands. Data products, including descriptive core logs, core photographs, results of sediment grain-size analyses, sample location maps, and geographic information system (GIS) data files with accompanying formal Federal Geographic Data Committee (FDGC) metadata can be downloaded from the data products and downloads page.

The SAMI Galaxy Survey: A prototype data archive for Big Science exploration

NASA Astrophysics Data System (ADS)

Konstantopoulos, I. S.; Green, A. W.; Foster, C.; Scott, N.; Allen, J. T.; Fogarty, L. M. R.; Lorente, N. P. F.; Sweet, S. M.; Hopkins, A. M.; Bland-Hawthorn, J.; Bryant, J. J.; Croom, S. M.; Goodwin, M.; Lawrence, J. S.; Owers, M. S.; Richards, S. N.

2015-11-01

We describe the data archive and database for the SAMI Galaxy Survey, an ongoing observational program that will cover ≈3400 galaxies with integral-field (spatially-resolved) spectroscopy. Amounting to some three million spectra, this is the largest sample of its kind to date. The data archive and built-in query engine use the versatile Hierarchical Data Format (HDF5), which precludes the need for external metadata tables and hence the setup and maintenance overhead those carry. The code produces simple outputs that can easily be translated to plots and tables, and the combination of these tools makes for a light system that can handle heavy data. This article acts as a contextual companion to the SAMI Survey Database source code repository, samiDB, which is freely available online and written entirely in Python. We also discuss the decisions related to the selection of tools and the creation of data visualisation modules. It is our aim that the work presented in this article-descriptions, rationale, and source code-will be of use to scientists looking to set up a maintenance-light data archive for a Big Science data load.

The Hopkins Ultraviolet Telescope: The Final Archive

NASA Astrophysics Data System (ADS)

Dixon, William V.; Blair, William P.; Kruk, Jeffrey W.; Romelfanger, Mary L.

2013-04-01

The Hopkins Ultraviolet Telescope (HUT) was a 0.9 m telescope and moderate-resolution (Δλ = 3 Å) far-ultraviolet (820-1850 Å) spectrograph that flew twice on the space shuttle, in 1990 December (Astro-1, STS-35) and 1995 March (Astro-2, STS-67). The resulting spectra were originally archived in a nonstandard format that lacked important descriptive metadata. To increase their utility, we have modified the original data-reduction software to produce a new and more user-friendly data product, a time-tagged photon list similar in format to the Intermediate Data Files (IDFs) produced by the Far Ultraviolet Spectroscopic Explorer calibration pipeline. We have transferred all relevant pointing and instrument-status information from locally-archived science and engineering databases into new FITS header keywords for each data set. Using this new pipeline, we have reprocessed the entire HUT archive from both missions, producing a new set of calibrated spectral products in a modern FITS format that is fully compliant with Virtual Observatory requirements. For each exposure, we have generated quick-look plots of the fully-calibrated spectrum and associated pointing history information. Finally, we have retrieved from our archives HUT TV guider images, which provide information on aperture positioning relative to guide stars, and converted them into FITS-format image files. All of these new data products are available in the new HUT section of the Mikulski Archive for Space Telescopes (MAST), along with historical and reference documents from both missions. In this article, we document the improved data-processing steps applied to the data and show examples of the new data products.

The Hopkins Ultraviolet Telescope: The Final Archive

NASA Technical Reports Server (NTRS)

Dixon, William V.; Blair, William P.; Kruk, Jeffrey W.; Romelfanger, Mary L.

2013-01-01

The Hopkins Ultraviolet Telescope (HUT) was a 0.9 m telescope and moderate-resolution (Delta)lambda equals 3 A) far-ultraviolet (820-1850 Å) spectrograph that flew twice on the space shuttle, in 1990 December (Astro-1, STS-35) and 1995 March (Astro-2, STS-67). The resulting spectra were originally archived in a nonstandard format that lacked important descriptive metadata. To increase their utility, we have modified the original datareduction software to produce a new and more user-friendly data product, a time-tagged photon list similar in format to the Intermediate Data Files (IDFs) produced by the Far Ultraviolet Spectroscopic Explorer calibration pipeline. We have transferred all relevant pointing and instrument-status information from locally-archived science and engineering databases into new FITS header keywords for each data set. Using this new pipeline, we have reprocessed the entire HUT archive from both missions, producing a new set of calibrated spectral products in a modern FITS format that is fully compliant with Virtual Observatory requirements. For each exposure, we have generated quicklook plots of the fully-calibrated spectrum and associated pointing history information. Finally, we have retrieved from our archives HUT TV guider images, which provide information on aperture positioning relative to guide stars, and converted them into FITS-format image files. All of these new data products are available in the new HUT section of the Mikulski Archive for Space Telescopes (MAST), along with historical and reference documents from both missions. In this article, we document the improved data-processing steps applied to the data and show examples of the new data products.

Recent advances and plans in processing and geocoding of SAR data at the DFD

NASA Technical Reports Server (NTRS)

Noack, W.

1993-01-01

Because of the needs of future projects like ENVISAT and the experiences made with the current operational ERS-1 facilities, a radical change in the synthetic aperture radar (SAR) processing scenarios can be predicted for the next years. At the German PAF several new developments were initialized which are driven mainly either by user needs or by system and operational constraints ('lessons learned'). At the end there will be a major simplification and uniformation of all used computer systems. Especially the following changes are likely to be implemented at the German PAF: transcription before archiving, processing of all standard products with high throughput directly at the receiving stations, processing of special 'high-valued' products at the PAF, usage of a single type of processor hardware, implementation of a large and fast on-line data archive, and improved and unified fast data network between the processing and archiving facilities. A short description of the current operational SAR facilities as well as the future implementations are given.

Method and system for the diagnosis of disease using retinal image content and an archive of diagnosed human patient data

DOEpatents

Tobin, Kenneth W; Karnowski, Thomas P; Chaum, Edward

2013-08-06

A method for diagnosing diseases having retinal manifestations including retinal pathologies includes the steps of providing a CBIR system including an archive of stored digital retinal photography images and diagnosed patient data corresponding to the retinal photography images, the stored images each indexed in a CBIR database using a plurality of feature vectors, the feature vectors corresponding to distinct descriptive characteristics of the stored images. A query image of the retina of a patient is obtained. Using image processing, regions or structures in the query image are identified. The regions or structures are then described using the plurality of feature vectors. At least one relevant stored image from the archive based on similarity to the regions or structures is retrieved, and an eye disease or a disease having retinal manifestations in the patient is diagnosed based on the diagnosed patient data associated with the relevant stored image(s).

Superfund Public Information System (SPIS), June 1998 (on CD-ROM). Data file

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-06-01

The Superfund Public Information System (SPIS) on CD-ROM contains Superfund data for the United States Environmental Protection Agency. The Superfund data is a collection of four databases, CERCLIS, Archive (NFRAP), RODS, and NPL Sites. Descriptions of these databases and CD contents are listed below. The FolioViews browse and retrieval engine is used as a graphical interface to the data. Users can access simple queries and can do complex searching on key words or fields. In addition, context sensitive help, a Superfund process overview, and an integrated data dictionary are available. RODS is the Records Of Decision System. RODS is usedmore » to track site clean-ups under the Superfund program to justify the type of treatment chosen at each site. RODS contains information on technology justification, site history, community participation, enforcement activities, site characteristics, scope and role of response action, and remedy. Explanation of Significant Differences (ESDs) are also available on the CD. CERCLIS is the Comprehensive Environmental Response, Compensation, and Liability Information System. It is the official repository for all Superfund site and incident data. It contains comprehensive information on hazardous waste sites, site inspections, preliminary assessments, and remedial status. The system is sponsored by the EPA`s Office of Emergency and Remedial Response, Information Management Center. Archive (NFRAP) consists of hazardous waste sites that have no further remedial action planned; only basic identifying information is provided for archive sites. The sites found in the Archive database were originally in the CERCLIS database, but were removed beginning in the fall of 1995. NPL sites (available online) are fact sheets that describe the location and history of Superfund sites. Included are descriptions of the most recent activities and past actions at the sites that have contributed to the contamination. Population estimates, land usages, and nearby resources give background on the local setting surrounding a site.« less

Creating Pathways for Low-Skill Adults: Lessons for Community and Technical Colleges from a Statewide Longitudinal Study

ERIC Educational Resources Information Center

Perry, Carol A.

2012-01-01

The purpose of this study was to examine the educational experiences and outcomes of low-skill adults in West Virginia's community and technical colleges, providing a more detailed profile of these students. Data for the variables were obtained from archival databases through a cooperative agreement between state agencies. Descriptive statistics…

Web-Resources for Astronomical Data in the Ultraviolet

NASA Astrophysics Data System (ADS)

Sachkov, M. E.; Malkov, O. Yu.

2017-12-01

In this paper we describe databases of space projects that are operating or have operated in the ultraviolet spectral region. We give brief descriptions and links to major sources for UV data on the web: archives, space mission sites, databases, catalogues. We pay special attention to the World Space Observatory—Ultraviolet mission that will be launched in 2021.

Preservation and Access to Manuscript Collections of the Czech National Library.

ERIC Educational Resources Information Center

Karen, Vladimir; Psohlavec, Stanislav

In 1996, the Czech National Library started a large-scale digitization of its extensive and invaluable collection of historical manuscripts and printed books. Each page of the selected documents is scanned using a high-resolution, full-color digital camera, processed, and archived on a CD-ROM disk. HTML coded description is added to the entire…

Toward a Model of Journal Economics in the Language Sciences. LINCS Project Document Series.

ERIC Educational Resources Information Center

Berg, Sanford; Campion, Douglas

This study outlines some considerations for an economic model of the scientific journal market. The model provides an explanation of journal market structure and the dynamics of market behavior, as well as a description of journal market development. Three types of periodicals are discussed: (1) primary, archival journals serving a current…

Working Together More than Alone: Students' Evolving Perceptions of Self and Community within a Four-Year Educational Administration Doctoral Cohort

ERIC Educational Resources Information Center

Ford, Lance; Vaughn, Courtney

2011-01-01

School administrators rarely have the opportunity to confer and share their challenges with colleagues. To address this problem in 2005 the Educational Administration Department (EAD) at Central University (a Midwestern PhD granting institution located in a thriving city of about 100,00 people) created a virtual/local doctoral cohort for 14 school…

The Transatlantic Defense Industrial Base: Restructuring Scenarios and Their Implications

DTIC Science & Technology

2005-04-01

construction of a transatlantic defense sector are tangible, but significant obstacles may accelerate the formation of a bipolar industrial base. While market...electronics powerhouse. Four months later, this combined entity merged with Dasa to form European Aeronautic Defence and Space Company (EADS). Construcciones ...producers, and aircraft engine makers, there is little left to consolidate within Europe. Directions des Constructions Navales (DCN), the French shipmaker

Environmental Affective Dispositions Scale (EADS): The Study of Validity and Reliability and Adaptation to Turkish

ERIC Educational Resources Information Center

Fettahlioglu, Pinar; Timur, Serkan; Timur, Betül

2016-01-01

The aim of this study is to conduct a research under circumstances of Turkey about the validity and reliability of the Affective Tendencies towards Environmental Scale prepared by Yavetz, Goldman and Pe'er (2009). The translation of this scale to Turkish was done by the researchers and language specialists. And then, the scale was evaluated by the…

Particulate air pollution induces arrhythmia via oxidative stress and calcium calmodulin kinase II activation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Jin-Bae; Kim, Changsoo; Choi, Eunmi

2012-02-15

Ambient particulate matter (PM) can increase the incidence of arrhythmia. However, the arrhythmogenic mechanism of PM is poorly understood. This study investigated the arrhythmogenic mechanism of PM. In Sprague–Dawley rats, QT interval was increased from 115.0 ± 14.0 to 142.1 ± 18.4 ms (p = 0.02) after endotracheal exposure of DEP (200 μg/ml for 30 min, n = 5). Ventricular premature contractions were more frequently observed after DEP exposure (100%) than baseline (20%, p = 0.04). These effects were prevented by pretreatment of N-acetylcysteine (NAC, 5 mmol/L, n = 3). In 12 Langendorff-perfused rat hearts, DEP infusion of 12.5 μg/mlmore » for 20 min prolonged action potential duration (APD) at only left ventricular base increasing apicobasal repolarization gradients. Spontaneous early afterdepolarization (EAD) and ventricular tachycardia (VT) were observed in 8 (67%) and 6 (50%) hearts, respectively, versus no spontaneous triggered activity or VT in any hearts before DEP infusion. DEP-induced APD prolongation, EAD and VT were successfully prevented with NAC (5 mmol/L, n = 5), nifedipine (10 μmol/L, n = 5), and active Ca{sup 2+}/calmodulin-dependent protein kinase II (CaMKII) blockade, KN 93 (1 μmol/L, n = 5), but not by thapsigargin (200 nmol/L) plus ryanodine (10 μmol/L, n = 5) and inactive CaMKII blockade, KN 92 (1 μmol/L, n = 5). In neonatal rat cardiomyocytes, DEP provoked ROS generation in dose dependant manner. DEP (12.5 μg/ml) induced apoptosis, and this effect was prevented by NAC and KN 93. Thus, this study shows that in vivo and vitro exposure of PM induced APD prolongation, EAD and ventricular arrhythmia. These effects might be caused by oxidative stress and CaMKII activation. -- Highlights: ► The ambient PM consistently prolonged repolarization. ► The ambient PM induced triggered activity and ventricular arrhythmia. ► These effects were prevented by antioxidants, I{sub CaL} blockade and CaMKII blockade. ► The ambient PM can induce arrhythmia via oxidative stress and activation of CaMKII.« less

Identification (GC and GC-MS) of unsaturated acetates in Elasmopalpus lignosellus and their biological activity (GC-EAD and EAG).

PubMed

Jham, Gulab N; da Silva, Alexsandro A; Lima, Eraldo R; Viana, Paulo

2005-02-01

Two insect colonies of Elasmopalpus lignosellus were reared in our laboratory, the first being initiated from pupae obtained from a cornfield in the region of Sete Lagoas, Minas Gerais and the second from a cornfield in the region of Goiânia, Goiás. From the two colonies, two extracts were prepared from the pheromone glands of virgin E. lignosellus females. The extract obtained from the first colony was designated as extract 1 while the extract obtained from the second colony was designated as extract 2. Extract 1 was analyzed by gas chromatography-mass spectrometry (GC-MS) with (Z)-9-hexadecenyl acetate [(Z)-9-HDA] and (Z)-11-hexadecenyl acetate [(Z)-11-HDA] being identified and confirmed by the formation of DMDS derivatives. In addition, a third acetate, which could be either (E)-8-hexadecenyl acetate [(E)-8-HDA] or (E)-9-hexadecenyl acetate [(E)-9-HDA] was detected by GC-MS. Extract 2 was analyzed by gas chromatography (GC) and gas chromatography-electroannetography (GC-EAD) revealing the presence of (Z)-11-HDA and (Z)-9-TDA. In addition, the same compounds elicited a response with the E. lignosellus male antenna obtained from the second insect colony. Electroantennography (EAG) screening with the male E. lignosellus antenna (obtained from the second insect colony) was conducted with the 23 possible tetradecenyl acetates (TDA) and 22 hexadecenyl acetates (HDA) as standards. Out of the 23 TDA isomers evaluated, only (Z)-9-TDA elicited a response and out of the 22 HDA [(Z) and (E) isomers gamma2 to delta13] evaluated only (Z)-11-HDA elicited a response. The acetate compositions of two extracts obtained from insects originating from the two states (Minas Gerais and Goiás) of Brazil were different from one another as well as from that obtained from insects in Tifton, GA, USA. The bioactivity data (GC-EAD) of the extract 2 differed from those reported for the Tifton, GA, USA population. These data suggest polymorphism in relation to the insect populations found in Brazil and in the USA. The possibility of the existence of an E. lignosellus sub-species cannot be ruled out.

Serologic response to Epstein-Barr virus antigens in patients with systemic lupus erythematosus: a controlled study.

PubMed

Esen, Bahar Artım; Yılmaz, Gülden; Uzun, Sami; Ozdamar, Melda; Aksözek, Alper; Kamalı, Sevil; Türkoğlu, Salih; Gül, Ahmet; Ocal, Lale; Aral, Orhan; Inanç, Murat

2012-01-01

Previous studies showed a link between systemic lupus erythematosus (SLE) and Epstein-Barr virus (EBV) infection. We sought to determine the features of serologic response to EBV in SLE patients and whether this response differs from those of systemic sclerosis (SSc) and primary antiphospholipid syndrome (PAPS) patients as well as healthy individuals. Sera from 198 consecutive SLE patients have been tested to detect IgG antibodies to EA/D, EBNA-1, VCA P18 and for comparison, cytomegalovirus (CMV) using commercially available ELISA kits (Trinity Biotech, USA). Forty-six SSc patients and 38 PAPS patients were enrolled as diseased control groups and sixty-five individuals as healthy controls. Significantly more SLE (54%, P = 0.001, OR 5.77, 95% CI 2.8-11.6), SSc (41.3%, P = 0.005, OR 3.4, 95% CI 1.4-8.2) and PAPS sera (36.8%, P = 0.023, OR 2.86, 95% CI 1.14-7.22) reacted against EA/D than healthy controls (16.9%). The mean age of anti-EA/D-positive SLE patients was significantly higher, and their disease duration was longer compared to anti-EA/D-negative SLE patients (41 ± 14 vs. 33.8 ± 10.8 years, P < 0.001 and 100 ± 73 vs. 71 ± 62 months, P = 0.003). In SLE patients, EA/D reactivity was associated with Raynaud's phenomenon and the presence of any anti-ENA antibodies. Although it did not reach a statistical significance, anti-EBNA-1 reactivity was slightly lower in patients with SLE. The frequency of anti-CMV Ig G positivity was found significantly higher in SLE patients (100%) when compared to patients with SSc (95.7%), PAPS (94.7%) and healthy controls (95.4%) (P = 0.035, P = 0.025 and P = 0.015 respectively). Our results support the proposed link between EBV and SLE. The finding that SSc and PAPS patients also have increased frequency of anti-EA/D response has revealed that this immune interaction may not be unique to patients with SLE, and there may be a common mechanism involving EBV in these autoimmune diseases.

Optical system for the Protein Crystallisation Diagnostics Facility (PCDF) on board the ISS

NASA Astrophysics Data System (ADS)

Joannes, Luc; Dupont, Olivier; Dewandel, Jean-Luc; Ligot, Renaud; Algrain, Hervé

2004-06-01

The Protein Crystallisation Diagnostic Facility (PCDF) is a multi-user facility to study the protein crystallisation under the conditions of micro-gravity onboard the International Space Station (ISS) Columbus facility. Large size protein crystals will growth under reduced gravity in thermally controlled reactors. A combination of diagnostic tools like video system, microscope, interferometer, and light scattering device shall help to understand the growth phenomena. Common methods of protein crystallisation shall be performed in PCDF: Dialysis where the protein solution and the salt solution are separated by a semi-permeable membrane. Extended Length Dialysis Batch where the saturation to get crystals is achieved by changing the concentration of the protein in the sample liquid. The overall ESA project is leaded by EADS Space Transportation, Friedrichshafen, Germany. Lambda-X is responsible for the Optical System (OS), with Verhaert Design and Development as sub-contractor for the mechanical design. The OS includes different compact parts: Original illumination systems based on LEDs of difference colours; Quantitative Mach-Zehnder interferometers to measure the concentration distribution around crystals; Imaging assemblies to visualize the protein volume with different field of views. The paper concentrates on the description of each part, and in particular on the imaging assembly which allow switching from one field of view to another by passive elements only.

Computer system design description for SY-101 hydrogen mitigation test project data acquisition and control system (DACS-1)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ermi, A.M.

1997-05-01

Description of the Proposed Activity/REPORTABLE OCCURRENCE or PIAB: This ECN changes the computer systems design description support document describing the computers system used to control, monitor and archive the processes and outputs associated with the Hydrogen Mitigation Test Pump installed in SY-101. There is no new activity or procedure associated with the updating of this reference document. The updating of this computer system design description maintains an agreed upon documentation program initiated within the test program and carried into operations at time of turnover to maintain configuration control as outlined by design authority practicing guidelines. There are no new crediblemore » failure modes associated with the updating of information in a support description document. The failure analysis of each change was reviewed at the time of implementation of the Systems Change Request for all the processes changed. This document simply provides a history of implementation and current system status.« less

Representation of viruses in the remediated PDB archive

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lawson, Catherine L., E-mail: cathy.lawson@rutgers.edu; Dutta, Shuchismita; Westbrook, John D.

2008-08-01

A new data model for PDB entries of viruses and other biological assemblies with regular noncrystallographic symmetry is described. A new scheme has been devised to represent viruses and other biological assemblies with regular noncrystallographic symmetry in the Protein Data Bank (PDB). The scheme describes existing and anticipated PDB entries of this type using generalized descriptions of deposited and experimental coordinate frames, symmetry and frame transformations. A simplified notation has been adopted to express the symmetry generation of assemblies from deposited coordinates and matrix operations describing the required point, helical or crystallographic symmetry. Complete correct information for building full assemblies,more » subassemblies and crystal asymmetric units of all virus entries is now available in the remediated PDB archive.« less

Conversion of a traditional image archive into an image resource on compact disc.

PubMed Central

Andrew, S M; Benbow, E W

1997-01-01

The conversion of a traditional archive of pathology images was organised on 35 mm slides into a database of images stored on compact disc (CD-ROM), and textual descriptions were added to each image record. Students on a didactic pathology course found this resource useful as an aid to revision, despite relative computer illiteracy, and it is anticipated that students on a new problem based learning course, which incorporates experience with information technology, will benefit even more readily when they use the database as an educational resource. A text and image database on CD-ROM can be updated repeatedly, and the content manipulated to reflect the content and style of the courses it supports. Images PMID:9306931

The long hold: Storing data at the National Archives

NASA Technical Reports Server (NTRS)

Thibodeau, Kenneth

1991-01-01

A description of the information collection and storage needs of the National Archives and Records Administration (NARA) is presented. The unique situation of NARA is detailed. Two aspects which make the issue of obsolescence especially complex and costly are dealing with incoherent data and satisfying unknown and unknowable requirements. The data is incoherent because it comes from a wide range of independent sources, covers unrelated subjects, and is organized and encoded in ways that are not only not controlled but often unknown until received. NARA's mission to preserve and provide access to records with enduring value makes NARA, in effect, the agent of future generations. NARA's responsibility to the future places itself is a perpetual quandary of devotion to serving needs which are unknown.

A user`s guide to LUGSAN II. A computer program to calculate and archive lug and sway brace loads for aircraft-carried stores

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dunn, W.N.

1998-03-01

LUG and Sway brace ANalysis (LUGSAN) II is an analysis and database computer program that is designed to calculate store lug and sway brace loads for aircraft captive carriage. LUGSAN II combines the rigid body dynamics code, SWAY85, with a Macintosh Hypercard database to function both as an analysis and archival system. This report describes the LUGSAN II application program, which operates on the Macintosh System (Hypercard 2.2 or later) and includes function descriptions, layout examples, and sample sessions. Although this report is primarily a user`s manual, a brief overview of the LUGSAN II computer code is included with suggestedmore » resources for programmers.« less

Mass-storage management for distributed image/video archives

NASA Astrophysics Data System (ADS)

Franchi, Santina; Guarda, Roberto; Prampolini, Franco

1993-04-01

The realization of image/video database requires a specific design for both database structures and mass storage management. This issue has addressed the project of the digital image/video database system that has been designed at IBM SEMEA Scientific & Technical Solution Center. Proper database structures have been defined to catalog image/video coding technique with the related parameters, and the description of image/video contents. User workstations and servers are distributed along a local area network. Image/video files are not managed directly by the DBMS server. Because of their wide size, they are stored outside the database on network devices. The database contains the pointers to the image/video files and the description of the storage devices. The system can use different kinds of storage media, organized in a hierarchical structure. Three levels of functions are available to manage the storage resources. The functions of the lower level provide media management. They allow it to catalog devices and to modify device status and device network location. The medium level manages image/video files on a physical basis. It manages file migration between high capacity media and low access time media. The functions of the upper level work on image/video file on a logical basis, as they archive, move and copy image/video data selected by user defined queries. These functions are used to support the implementation of a storage management strategy. The database information about characteristics of both storage devices and coding techniques are used by the third level functions to fit delivery/visualization requirements and to reduce archiving costs.

ARCUS Internet Media Archive (IMA): A Resource for Outreach and Education

NASA Astrophysics Data System (ADS)

Polly, Z.; Warnick, W. K.; Polly, J.

2008-12-01

The ARCUS Internet Media Archive (IMA) is a collection of photos, graphics, videos, and presentations about the Arctic that are shared through the Internet. It provides the arctic research community and the public at large with a centralized location where images and video pertaining to polar research can be browsed and retrieved for a variety of uses. The IMA currently contains almost 6,500 publicly accessible photos, including 4,000 photos from the National Science Foundation funded Teachers and Researchers Exploring and Collaborating (TREC, now PolarTREC) program, an educational research experience in which K-12 teachers participate in arctic research as a pathway to improving science education. The IMA also includes 450 video files, 270 audio files, nearly 100 graphics and logos, 28 presentations, and approximately 10,000 additional resources that are being prepared for public access. The contents of this archive are organized by file type, contributor's name, event, or by organization, with each photo or file accompanied by information on content, contributor source, and usage requirements. All the files are key-worded and all information, including file name and description, is completely searchable. ARCUS plans to continue to improve and expand the IMA with a particular focus on providing graphics depicting key arctic research results and findings as well as edited video archives of relevant scientific community meetings. To submit files or for more information and to view the ARCUS Internet Media Archive, please go to: http://media.arcus.org or email photo@arcus.org.

ARCUS Internet Media Archive (IMA): A Window Into the Arctic - An Online Resource for Education and Outreach

NASA Astrophysics Data System (ADS)

Buxbaum, T. M.; Warnick, W. K.; Polly, B.; Hueffer, L. J.; Behr, S. A.

2006-12-01

The ARCUS Internet Media Archive (IMA) is a collection of photos, graphics, videos, and presentations about the Arctic that are shared through the Internet. It provides the arctic research community and the public at large with a centralized location where images and video pertaining to polar research can be browsed and retrieved for a variety of uses. The IMA currently contains almost 5,000 publicly accessible photos, including 3,000 photos from the National Science Foundation funded Teachers and Researchers Exploring and Collaborating (TREC) program, an educational research experience in which K-12 teachers participate in arctic research as a pathway to improving science education. The IMA also includes 360 video files, 260 audio files, and approximately 8,000 additional resources that are being prepared for public access. The contents of this archive are organized by file type, contributor's name, event, or by organization, with each photo or file accompanied by information on content, contributor source, and usage requirements. All the files are keyworded and all information, including file name and description, is completely searchable. ARCUS plans to continue to improve and expand the IMA with a particular focus on providing graphics depicting key arctic research results and findings as well as edited video archives of relevant scientific community meetings.

MAXIECPC: Theoretical Background and Descriptive Research on General Statistics, Frequency Words and Keywords

ERIC Educational Resources Information Center

Calzada Pérez, María

2013-01-01

The present paper revolves around MaxiECPC, one of the various sub-corpora that make up ECPC (the European Comparable and Parallel Corpora), an electronic archive of speeches delivered at different parliaments (i.e. the European Parliament-EP; the Spanish Congreso de los Diputados-CD; and the British House of Commons-HC) from 1996 to 2009. In…

Fallon, Nevada FORGE Thermal-Hydrological-Mechanical Models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blankenship, Doug; Sonnenthal, Eric

Archive contains thermal-mechanical simulation input/output files. Included are files which fall into the following categories: ( 1 ) Spreadsheets with various input parameter calculations ( 2 ) Final Simulation Inputs ( 3 ) Native-State Thermal-Hydrological Model Input File Folders ( 4 ) Native-State Thermal-Hydrological-Mechanical Model Input Files ( 5 ) THM Model Stimulation Cases See 'File Descriptions.xlsx' resource below for additional information on individual files.

Guide to the Records Relating to Science and Technology in the British Public Record Office: A RAMP Study.

ERIC Educational Resources Information Center

Jubb, Michael

Prepared under contract with the International Council on Archives (ICA), this guide provides descriptions of all classes of public records held by the British Public Record Office (PRO) which are likely to contain scientific or technical information. The PRO is responsible for keeping and making available to the public those records of the…

Sediment data collected in 2013 from the northern Chandeleur Islands, Louisiana

USGS Publications Warehouse

Buster, Noreen A.; Kelso, Kyle W.; Bernier, Julie C.; Flocks, James G.; Miselis, Jennifer L.; DeWitt, Nancy T.

2014-01-01

This data series serves as an archive of sediment data collected in July 2013 from the Chandeleur Islands sand berm and adjacent barrier-island environments. Data products include descriptive core logs, core photographs and x-radiographs, results of sediment grain-size analyses, sample location maps, and Geographic Information System data files with accompanying formal Federal Geographic Data Committee metadata.

The Archives of the Department of Terrestrial Magnetism: Documenting 100 Years of Carnegie Science

NASA Astrophysics Data System (ADS)

Hardy, S. J.

2005-12-01

The archives of the Department of Terrestrial Magnetism (DTM) of the Carnegie Institution of Washington document more than a century of geophysical and astronomical investigations. Primary source materials available for historical research include field and laboratory notebooks, equipment designs, plans for observatories and research vessels, scientists' correspondence, and thousands of expedition and instrument photographs. Yet despite its history, DTM long lacked a systematic approach to managing its documentary heritage. A preliminary records survey conducted in 2001 identified more than 1,000 linear feet of historically-valuable records languishing in dusty, poorly-accessible storerooms. Intellectual control at that time was minimal. With support from the National Historical Publications and Records Commission, the "Carnegie Legacy Project" was initiated in 2003 to preserve, organize, and facilitate access to DTM's archival records, as well as those of the Carnegie Institution's administrative headquarters and Geophysical Laboratory. Professional archivists were hired to process the 100-year backlog of records. Policies and procedures were established to ensure that all work conformed to national archival standards. Records were appraised, organized, and rehoused in acid-free containers, and finding aids were created for the project web site. Standardized descriptions of each collection were contributed to the WorldCat bibliographic database and the AIP International Catalog of Sources for History of Physics. Historic photographs and documents were digitized for online exhibitions to raise awareness of the archives among researchers and the general public. The success of the Legacy Project depended on collaboration between archivists, librarians, historians, data specialists, and scientists. This presentation will discuss key aspects (funding, staffing, preservation, access, outreach) of the Legacy Project and is aimed at personnel in observatories, research institutes, and other organizations interested in establishing their own archival programs.

76 FR 53324 - Airworthiness Directives; Agusta S.p.A. Model A109A, A109A II, A109C, and A109K2 Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-26

... Airworthiness Directives; Agusta S.p.A. Model A109A, A109A II, A109C, and A109K2 Helicopters AGENCY: Federal... helicopters. That EAD currently requires inspecting the main rotor scissor fitting assembly to determine if... helicopter. DATES: Effective September 12, 2011. The incorporation by reference of certain publications...

NATO Standardization and Licensing Policy - Exploratory Phase. Volume 2. Main Report

DTIC Science & Technology

1976-11-30

issued under this section, every person who engages in the business of manufacturing, exporting, or importing arms, ammunition, or implements of... Wiliiam C. Pettijohn, Consultant Arthur Tyler Port, Consultant George M. Sr.ead, Jr. and Hoagland, MacLachlan & Co., Inc., Subcontractor 8...support in obtaining interviews with busy officials. The views and judgments expressed in this report are those of the authors and do not

Proceedings of the Conference of the International Group for the Psychology of Mathematics Education (30th, Prague, Czech Republic, July 16-21, 2006). Volume 3

ERIC Educational Resources Information Center

Novotna, Jarmila, Ed.; Moraova, Hana, Ed.; Kratka, Magdalena, Ed.; Stehlikova, Nad'a, Ed.

2006-01-01

This document contains the third volume of the proceedings of the 30th Conference of the International Group for the Psychology of Mathematics Education. Conference presentations are centered around the theme "Mathematics at the Centre." This volume features 60 research reports by presenters with last names beginning between Ead and Kou:…

Helium High Pressure Tanks at EADS Space Transportation New Technology with Thermoplastic Liner

DTIC Science & Technology

2005-07-13

l’art actuel pour l’application d’un liner thermoplastique sur le réservoir hélium 300 litres pour le lanceur ARIANE 5, réservoir actuellement réalisé à...L à liner thermoplastique ont complètement démontré le respect aux exigences majeures demandées pour le lanceur A5. Ces travaux finalisent la phase

Lipidomics comparing DCD and DBD liver allografts uncovers lysophospholipids elevated in recipients undergoing early allograft dysfunction.

PubMed

Xu, Jin; Casas-Ferreira, Ana M; Ma, Yun; Sen, Arundhuti; Kim, Min; Proitsi, Petroula; Shkodra, Maltina; Tena, Maria; Srinivasan, Parthi; Heaton, Nigel; Jassem, Wayel; Legido-Quigley, Cristina

2015-12-04

Finding specific biomarkers of liver damage in clinical evaluations could increase the pool of available organs for transplantation. Lipids are key regulators in cell necrosis and hence this study hypothesised that lipid levels could be altered in organs suffering severe ischemia. Matched pre- and post-transplant biopsies from donation after circulatory death (DCD, n = 36, mean warm ischemia time = 2 min) and donation after brain death (DBD, n = 76, warm ischemia time = none) were collected. Lipidomic discovery and multivariate analysis (MVA) were applied. Afterwards, univariate analysis and clinical associations were conducted for selected lipids differentiating between these two groups. MVA grouped DCD vs. DBD (p = 6.20 × 10(-12)) and 12 phospholipids were selected for intact lipid measurements. Two lysophosphatidylcholines, LysoPC (16:0) and LysoPC (18:0), showed higher levels in DCD at pre-transplantation (q < 0.01). Lysophosphatidylcholines were associated with aspartate aminotransferase (AST) 14-day post-transplantation (q < 0.05) and were more abundant in recipients undergoing early allograft dysfunction (EAD) (p < 0.05). A receiver-operating characteristics (ROC) curve combining both lipid levels predicted EAD with 82% accuracy. These findings suggest that LysoPC (16:0) and LysoPC (18:0) might have a role in signalling liver tissue damage due to warm ischemia before transplantation.

Bulk-surface relationship of an electronic structure for high-throughput screening of metal oxide catalysts

NASA Astrophysics Data System (ADS)

Kweun, Joshua Minwoo; Li, Chenzhe; Zheng, Yongping; Cho, Maenghyo; Kim, Yoon Young; Cho, Kyeongjae

2016-05-01

Designing metal-oxides consisting of earth-abundant elements has been a crucial issue to replace precious metal catalysts. To achieve efficient screening of metal-oxide catalysts via bulk descriptors rather than surface descriptors, we investigated the relationship between the electronic structure of bulk and that of the surface for lanthanum-based perovskite oxides, LaMO3 (M = Ti, V, Cr, Mn, Fe, Co, Ni, Cu). Through density functional theory calculations, we examined the d-band occupancy of the bulk and surface transition-metal atoms (nBulk and nSurf) and the adsorption energy of an oxygen atom (Eads) on (001), (110), and (111) surfaces. For the (001) surface, we observed strong correlation between the nBulk and nSurf with an R-squared value over 94%, and the result was interpreted in terms of ligand field splitting and antibonding/bonding level splitting. Moreover, the Eads on the surfaces was highly correlated with the nBulk with an R-squared value of more than 94%, and different surface relaxations could be explained by the bulk electronic structure (e.g., LaMnO3 vs. LaTiO3). These results suggest that a bulk-derived descriptor such as nBulk can be used to screen metal-oxide catalysts.

Person-Based Versus Generalized Impulsivity Disinhibition in Frontotemporal Dementia and Alzheimer Disease.

PubMed

Paholpak, Pongsatorn; Carr, Andrew R; Barsuglia, Joseph P; Barrows, Robin J; Jimenez, Elvira; Lee, Grace J; Mendez, Mario F

2016-09-19

While much disinhibition in dementia results from generalized impulsivity, in behavioral variant frontotemporal dementia (bvFTD) disinhibition may also result from impaired social cognition. To deconstruct disinhibition and its neural correlates in bvFTD vs. early-onset Alzheimer's disease (eAD). Caregivers of 16 bvFTD and 21 matched-eAD patients completed the Frontal Systems Behavior Scale disinhibition items. The disinhibition items were further categorized into (1) "person-based" subscale which predominantly associated with violating social propriety and personal boundary and (2) "generalized-impulsivity" subscale which included nonspecific impulsive acts. Subscale scores were correlated with grey matter volumes from tensor-based morphometry on magnetic resonance images. In comparison to the eAD patients, the bvFTD patients developed greater person-based disinhibition (P < 0.001) but comparable generalized impulsivity. Severity of person-based disinhibition significantly correlated with the left anterior superior temporal sulcus (STS), and generalized-impulsivity correlated with the right orbitofrontal cortex (OFC) and the left anterior temporal lobe (aTL). Person-based disinhibition was predominant in bvFTD and correlated with the left STS. In both dementia, violations of social propriety and personal boundaries involved fronto-parieto-temporal network of Theory of Mind, whereas nonspecific disinhibition involved the OFC and aTL. © The Author(s) 2016.

Productive infection of Epstein-Barr virus (EBV) in EBV-genome-positive epithelial cell lines (GT38 and GT39) derived from gastric tissues.

PubMed

Takasaka, N; Tajima, M; Okinaga, K; Satoh, Y; Hoshikawa, Y; Katsumoto, T; Kurata, T; Sairenji, T

1998-08-01

We characterized the expression of Epstein-Barr virus (EBV) on two epithelial cell lines, GT38 and GT39, derived from human gastric tissues. The EBV nuclear antigen (EBNA) was detected in all cells of both cell lines. The EBV immediate-early BZLF 1 protein (ZEBRA), the early antigen diffuse component (EA-D), and one of the EBV envelope proteins (gp350/220) were expressed spontaneously in small proportions in the cells. EBNA 1, EBNA2, latent membrane protein 1, ZEBRA, and EA-D molecules were then observed by Western blotting in the cells. The lytic cycle was enhanced with treatment with 12-O-tetradecanoylphorbol-13-acetate (TPA) or n-butyrate. The virus particles were observed in the TPA treated GT38 cells by electron microscopy. Infectious EBV was detected with the transformation of cord blood lymphocytes and also with the induction of early antigen to Raji cells by the supernatants of both cells lines. A major single and minor multiple fused terminal fragments and a ladder of smaller fragments of the EBV genome were detected with a Xhol probe in both cell lines. These epithelial cells lines and viruses will be useful in studying their association with EBV in gastric epithelial cells.

Fabrication of arc-induced long-period gratings in different silica fibers

NASA Astrophysics Data System (ADS)

Ranjan, Rajeev; Esposito, Flavio; Campopiano, Stefania; Iadicicco, Agostino

2017-05-01

In this work, we report on recent results about the fabrication of Long Period Gratings (LPGs) in different single mode optical fibers, by means of Electric Arc Discharge (EAD) technique. In particular, the results are related to three optical fibers with different doping elements, i.e.: standard telecommunication Ge-doped SMF28, highly photosensitive B/Gecodoped PS1250/1500, and P-doped P-SM-5 fibers. EAD leads to a point-by-point LPG inscription, due to localized tapering of the transversal size of the core and cladding regions along the fiber, and to changes of the silica refractive index due to the stress relaxation induced by local hot spots. Here, we take into consideration both standard and unconventional silica fibers and the aim of the work is to identify an appropriate "recipe" for each fiber, for manufacturing LPGs with strong and narrow attenuation bands (depth higher than 25 dB) and trivial power losses (<0.5 dB). Indeed, a proper combination of arc power and duration, as well as fiber tension, allows for the appropriate core and cladding modulation and thus for the desired LPGs spectral features. The sensitivity characteristics towards surrounding refractive index (SRI) and temperature changes of these LPGs are also investigated, highlighting the effects of different kind of doping.

Text-to-phonemic transcription and parsing into mono-syllables of English text

NASA Astrophysics Data System (ADS)

Jusgir Mullick, Yugal; Agrawal, S. S.; Tayal, Smita; Goswami, Manisha

2004-05-01

The present paper describes a program that converts the English text (entered through the normal computer keyboard) into its phonemic representation and then parses it into mono-syllables. For every letter a set of context based rules is defined in lexical order. A default rule is also defined separately for each letter. Beginning from the first letter of the word the rules are checked and the most appropriate rule is applied on the letter to find its actual orthographic representation. If no matching rule is found, then the default rule is applied. Current rule sets the next position to be analyzed. Proceeding in the same manner orthographic representation for each word can be found. For example, ``reading'' is represented as ``rEdiNX'' by applying the following rules: r-->r move 1 position ahead ead-->Ed move 3 position ahead i-->i move 1 position ahead ng-->NX move 2 position ahead, i.e., end of word. The phonemic representations obtained from the above procedure are parsed to get mono-syllabic representation for various combinations such as CVC, CVCC, CV, CVCVC, etc. For example, the above phonemic representation will be parsed as rEdiNX---> /rE/ /diNX/. This study is a part of developing TTS for Indian English.

Towards Data Repository Interoperability: The Data Conservancy Data Packaging Specification

NASA Astrophysics Data System (ADS)

DiLauro, T.; Duerr, R.; Thessen, A. E.; Rippin, M.; Pralle, B.; Choudhury, G. S.

2013-12-01

A modern data archive must support a variety of functions and services for a broad set of stakeholders over a variety of content. Data producers need to deposit this content; data consumers need to find and access it; journal publishers need to link to and from it; funders need to ensure that it is protected and its value enhanced; research institutions need to track it; and the archive itself needs to manage and preserve it. But there is not an optimal information model that supports all of these tasks. The attributes needed to manage format transformations for long-term preservation are different from, for example, those needed to understand provenance relationships among the various entities modeled in the archive. Exposing all possible properties to every function burdens users and makes it difficult to maintain a separation of concerns among the functional components. The Data Conservancy Software (DCS) manages these overlapping information needs by defining strict interfaces between components and providing mappers between the layers of the architecture. Still, work remains to make deposit more intuitive. Currently, depositing content into a DCS instance requires either very simple objects (e.g., one file equals one data item), significant manual effort, or detailed knowledge of DCS-internal data model serializations. And if one were to deposit that content into another type of archive, it would be necessary to repeat this effort. To allow data producers and consumers to interact with data in a more natural manner, the Data Conservancy[1] is developing a packaging approach that eases this burden and allows a semantic overlay atop the directory/folder and file metaphor that is more familiar. The standards-based packaging scheme augments the payload and validation capabilities of Bagit[2] with the relationship and resource description capabilities of the Open Archives Initiative (OAI) Object Reuse and Exchange (ORE)[3] model. In the absence of the ORE resource description, the DCS instance will be able to provide default mappings for the directories and files within the package payload and enable support for deposited content at a lower level of service. Internally, the DCS will map these hybrid package serializations to its own internal business objects and their properties. Thus, this approach is highly extensible, as other packaging formats could be mapped in a similar manner. In addition, this scheme supports establishing the fixity of the payload while still supporting update of the semantic overlay data. This allows a data producer with scarce resources or an archivist who acquires a researcher's data to package the data for deposit with the intention of augmenting the resource description in the future. The Data Conservancy is partnering with the Sustainable Environment Actionable Data[4] project to test the interoperability of this new packaging mechanism. [1] Data Conservancy: http://dataconservancy.org/ [2] BagIt: https://datatracker.ietf.org/doc/draft-kunze-bagit/ [3] OAI-ORE: http://www.openarchives.org/ore/1.0/ [4] SEAD: http://sead-data.net/

An XML-based Generic Tool for Information Retrieval in Solar Databases

NASA Astrophysics Data System (ADS)

Scholl, Isabelle F.; Legay, Eric; Linsolas, Romain

This paper presents the current architecture of the `Solar Web Project' now in its development phase. This tool will provide scientists interested in solar data with a single web-based interface for browsing distributed and heterogeneous catalogs of solar observations. The main goal is to have a generic application that can be easily extended to new sets of data or to new missions with a low level of maintenance. It is developed with Java and XML is used as a powerful configuration language. The server, independent of any database scheme, can communicate with a client (the user interface) and several local or remote archive access systems (such as existing web pages, ftp sites or SQL databases). Archive access systems are externally described in XML files. The user interface is also dynamically generated from an XML file containing the window building rules and a simplified database description. This project is developed at MEDOC (Multi-Experiment Data and Operations Centre), located at the Institut d'Astrophysique Spatiale (Orsay, France). Successful tests have been conducted with other solar archive access systems.

Extracting scientific articles from a large digital archive: BioStor and the Biodiversity Heritage Library

PubMed Central

2011-01-01

Background The Biodiversity Heritage Library (BHL) is a large digital archive of legacy biological literature, comprising over 31 million pages scanned from books, monographs, and journals. During the digitisation process basic metadata about the scanned items is recorded, but not article-level metadata. Given that the article is the standard unit of citation, this makes it difficult to locate cited literature in BHL. Adding the ability to easily find articles in BHL would greatly enhance the value of the archive. Description A service was developed to locate articles in BHL based on matching article metadata to BHL metadata using approximate string matching, regular expressions, and string alignment. This article locating service is exposed as a standard OpenURL resolver on the BioStor web site http://biostor.org/openurl/. This resolver can be used on the web, or called by bibliographic tools that support OpenURL. Conclusions BioStor provides tools for extracting, annotating, and visualising articles from the Biodiversity Heritage Library. BioStor is available from http://biostor.org/. PMID:21605356

Policy Windows, Public Opinion, and Policy Ideas: The Evolution of No Child Left Behind

ERIC Educational Resources Information Center

Jaiani, Vasil; Whitford, Andrew B.

2011-01-01

Purpose: The purpose of this paper is to examine the policy process that led to the passage of the No Child Left Behind (NCLB) Act in the United States and the Bush Administration's role in this process. Design/methodology/approach: The research design is historical and archival. A description of the NCLB Act is given and the major provisions and…

The DMSP Space Weather Sensors Data Archive Listing (1982-2013) and File Formats Descriptions

DTIC Science & Technology

2014-08-01

environment sensors including the auroral particle spectrometer (SSJ), the fluxgate magnetometer (SSM), the topside thermal plasma monitor (SSIES... Fluxgate Magnetometer (SSM) for the Defense Meteorological Satellite Program (DMSP) Block 5D-2, Flight 7, Instrument Papers, AFGL-TR-84-0225; ADA155229...Flux) SSM The fluxgate magnetometer . (Special Sensor, Magnetometer ) SSULI The ultraviolet limb imager SSUSI The ultraviolet spectrographic imager

Peacetime Military Engagement: A Framework for Policy Criteria

DTIC Science & Technology

1993-08-01

policy of Military Cooperation Program to use some enggin n ha ce ogeraions b i military resources on the domestic front to ead suld focusimiltaeresous...authority deals with the need for greater handle the industrial base problems that arise flexibility in the effective use of the increasing when defense...Current efforts in the that U.S. industrial mobilization for major, DoD are largely being directed at removing that sustained warfare is unlikely. A

Why did Poland Choose the F-16

DTIC Science & Technology

2007-06-01

study then outlines the financial construct of the three bids, to include economic issues and pressures from the U.S., French, and Swedish governments...multipliers) 1 EADS Construcciones Aeronáuticas (Spain) Delivery of C295M transport aircraft for Polish Air Force 28 Aug 2001 $212.04M 2 GEIE Eurptorp...cooperation in, among others, ship construction , and steel industry, as well as assistance in road management and maintenance.”79 The Swedish (Saab

Defense Science Board 2005 Summer Study on Transformation: A Progress Assessment. Volume 2. Supporting Reports

DTIC Science & Technology

2006-04-01

Banking Mr. Robert Luby, IBM Dr. Robert Lucky, Telcordia Technologies Mr. William Lynn, Raytheon Mr. Dave Oliver, EADS North America GOVERNMENT...MAY 2005 Central Command (CENTCOM) COL Peter Zielinski CENTCOM Office of Force Transformation (OFT) Review of COCOM Experimentation COL Richard...for Defense Analyses Mr. Patrick McCarthy, U.S. Joint Forces Command Mr. Stephen Moore, U.S. Joint Forces Command MAY 10, 2005 COL Peter Zielinski

Adapt

NASA Astrophysics Data System (ADS)

Bargatze, L. F.

2015-12-01

Active Data Archive Product Tracking (ADAPT) is a collection of software routines that permits one to generate XML metadata files to describe and register data products in support of the NASA Heliophysics Virtual Observatory VxO effort. ADAPT is also a philosophy. The ADAPT concept is to use any and all available metadata associated with scientific data to produce XML metadata descriptions in a consistent, uniform, and organized fashion to provide blanket access to the full complement of data stored on a targeted data server. In this poster, we present an application of ADAPT to describe all of the data products that are stored by using the Common Data File (CDF) format served out by the CDAWEB and SPDF data servers hosted at the NASA Goddard Space Flight Center. These data servers are the primary repositories for NASA Heliophysics data. For this purpose, the ADAPT routines have been used to generate data resource descriptions by using an XML schema named Space Physics Archive, Search, and Extract (SPASE). SPASE is the designated standard for documenting Heliophysics data products, as adopted by the Heliophysics Data and Model Consortium. The set of SPASE XML resource descriptions produced by ADAPT includes high-level descriptions of numerical data products, display data products, or catalogs and also includes low-level "Granule" descriptions. A SPASE Granule is effectively a universal access metadata resource; a Granule associates an individual data file (e.g. a CDF file) with a "parent" high-level data resource description, assigns a resource identifier to the file, and lists the corresponding assess URL(s). The CDAWEB and SPDF file systems were queried to provide the input required by the ADAPT software to create an initial set of SPASE metadata resource descriptions. Then, the CDAWEB and SPDF data repositories were queried subsequently on a nightly basis and the CDF file lists were checked for any changes such as the occurrence of new, modified, or deleted files, or the addition of new or the deletion of old data products. Next, ADAPT routines analyzed the query results and issued updates to the metadata stored in the UCLA CDAWEB and SPDF metadata registries. In this way, the SPASE metadata registries generated by ADAPT can be relied on to provide up to date and complete access to Heliophysics CDF data resources on a daily basis.

Documenting of Geologic Field Activities in Real-Time in Four Dimensions: Apollo 17 as a Case Study for Terrestrial Analogues and Future Exploration

NASA Technical Reports Server (NTRS)

Feist, B.; Bleacher, J. E.; Petro, N. E.; Niles, P. B.

2018-01-01

During the Apollo exploration of the lunar surface, thousands of still images, 16 mm videos, TV footage, samples, and surface experiments were captured and collected. In addition, observations and descriptions of what was observed was radioed to Mission Control as part of standard communications and subsequently transcribed. The archive of this material represents perhaps the best recorded set of geologic field campaigns and will serve as the example of how to conduct field work on other planetary bodies for decades to come. However, that archive of material exists in disparate locations and formats with varying levels of completeness, making it not easily cross-referenceable. While video and audio exist for the missions, it is not time synchronized, and images taken during the missions are not time or location tagged. Sample data, while robust, is not easily available in a context of where the samples were collected, their descriptions by the astronauts are not connected to them, or the video footage of their collection (if available). A more than five year undertaking to reconstruct and reconcile the Apollo 17 mission archive, from launch through splashdown, has generated an integrated record of the entire mission, resulting in searchable, synchronized image, voice, and video data, with geologic context provided at the time each sample was collected. Through www.apollo17.org the documentation of the field investigation conducted by the Apollo 17 crew is presented in chronologic sequence, with additional context provided by high-resolution Lunar Reconnaissance Orbiter Camera (LROC) Narrow Angle Camera (NAC) images and a corresponding digital terrain model (DTM) of the Taurus-Littrow Valley.

Imaged document information location and extraction using an optical correlator

NASA Astrophysics Data System (ADS)

Stalcup, Bruce W.; Dennis, Phillip W.; Dydyk, Robert B.

1999-12-01

Today, the paper document is fast becoming a thing of the past. With the rapid development of fast, inexpensive computing and storage devices, many government and private organizations are archiving their documents in electronic form (e.g., personnel records, medical records, patents, etc.). Many of these organizations are converting their paper archives to electronic images, which are then stored in a computer database. Because of this, there is a need to efficiently organize this data into comprehensive and accessible information resources and provide for rapid access to the information contained within these imaged documents. To meet this need, Litton PRC and Litton Data Systems Division are developing a system, the Imaged Document Optical Correlation and Conversion System (IDOCCS), to provide a total solution to the problem of managing and retrieving textual and graphic information from imaged document archives. At the heart of IDOCCS, optical correlation technology provide a means for the search and retrieval of information from imaged documents. IDOCCS can be used to rapidly search for key words or phrases within the imaged document archives and has the potential to determine the types of languages contained within a document. In addition, IDOCCS can automatically compare an input document with the archived database to determine if it is a duplicate, thereby reducing the overall resources required to maintain and access the document database. Embedded graphics on imaged pages can also be exploited, e.g., imaged documents containing an agency's seal or logo can be singled out. In this paper, we present a description of IDOCCS as well as preliminary performance results and theoretical projections.

The human-induced pluripotent stem cell initiative—data resources for cellular genetics

PubMed Central

Streeter, Ian; Harrison, Peter W.; Faulconbridge, Adam; Flicek, Paul; Parkinson, Helen; Clarke, Laura

2017-01-01

The Human Induced Pluripotent Stem Cell Initiative (HipSci) isf establishing a large catalogue of human iPSC lines, arguably the most well characterized collection to date. The HipSci portal enables researchers to choose the right cell line for their experiment, and makes HipSci's rich catalogue of assay data easy to discover and reuse. Each cell line has genomic, transcriptomic, proteomic and cellular phenotyping data. Data are deposited in the appropriate EMBL-EBI archives, including the European Nucleotide Archive (ENA), European Genome-phenome Archive (EGA), ArrayExpress and PRoteomics IDEntifications (PRIDE) databases. The project will make 500 cell lines from healthy individuals, and from 150 patients with rare genetic diseases; these will be available through the European Collection of Authenticated Cell Cultures (ECACC). As of August 2016, 238 cell lines are available for purchase. Project data is presented through the HipSci data portal (http://www.hipsci.org/lines) and is downloadable from the associated FTP site (ftp://ftp.hipsci.ebi.ac.uk/vol1/ftp). The data portal presents a summary matrix of the HipSci cell lines, showing available data types. Each line has its own page containing descriptive metadata, quality information, and links to archived assay data. Analysis results are also available in a Track Hub, allowing visualization in the context of public genomic annotations (http://www.hipsci.org/data/trackhubs). PMID:27733501

Description of data on the Nimbus 7 LIMS map archive tape: Water vapor and nitrogen dioxide

NASA Technical Reports Server (NTRS)

Haggard, Kenneth V.; Marshall, B. T.; Kurzeja, Robert J.; Remsberg, Ellis E.; Russell, James M., III

1988-01-01

Described is the process by which the analysis of the Limb Infrared Monitor of the Stratosphere (LIMS) experiment data were used to produce estimates of synoptic maps of water vapor and nitrogen dioxide. In addition to a detailed description of the analysis procedure, also discussed are several interesting features in the data which are used to demonstrate how the analysis procedure produced the final maps and how one can estimate the uncertainties in the maps. In addition, features in the analysis are noted that would influence how one might use, or interpret, the results. These include subjects such as smoothing and the interpretation of wave components.

Descriptive Biomarkers for Assessing Breast Cancer Risk

DTIC Science & Technology

2011-10-01

studies are being conducted with the archived milk samples. 15. SUBJECT TERMS Breast milk; recruitment; promoter hypermethylation; RASSF1, GSTP1 ...difference between the two populations is the greater number of outlier scores in the Biopsy Group, particularly for GSTP1 . This might be expected given...Biopsy and Reference Groups. The percentage of outlier scores is significantly greater in the Biopsy Group than in the Reference Group for GSTP1

Novel Developments in Organonitrogen Fluorine Chemistry from Carbon- Nitrogen

DTIC Science & Technology

1991-11-21

alkan- imines (R.FC-NBr, P.R CF3. C2 F5, n-C3F7, CF2CI. CCI3). Photolyuis of the perfluorinated N-bromo compounds af- fords the novel perfluoroazines...physical properties. Alternative and improved I syntheses of three compounds are also reported. The perfluorinated N-haloimines, CF 2-NX (X = F, Cl...ihenakaif e anibokn i ls eatv ncephl ndncepii sbTitutionths reactions ead toetdsrutrso a variety of novelrgni compounds . Ofseilitrsoaftedaiiie

An Interactive Activation Model of the Effect of Context in Perception. Part I.

DTIC Science & Technology

1980-05-15

interested in word perception (Adams, 1979; Estes, 1975; LaBerge & Samuels, 1974; Johnston & McClelland, in press; McClelland, 1976). Our model differs from... LaBerge , D., & Samuels, S. Toward a theory of automatic information process- ing in -eading. Cognitive Psychology, 1974, 6, 293-323. Levin, J. A...Frederick Hayes-Roth I DR. ALBERT STEVENS Stanford University The lad Corporation BOLT BRINEX 4 NEWMAN, INC. Stanford, CA 94305 1700 Main Street 50

Growth and Metabolism of Three Introduced Summersed Plant Species in Relation to the Influences of Temperature and Light.

DTIC Science & Technology

1980-10-01

Hydrilla Photosynthesis TRAcr (camae, ai toevm it o neeemvo ead entit by block rnn&er) Under controlled experimental conditions, the influences of...five levels ranging between 161 and 32"C. Growth considerations included morphology, bio- mass, and nutrition. Photosynthesis , respiration, and CO𔃻...and promoted a com- pression of the growth cycle. The relationship between photosynthesis and respiration (P:R) was appreciably reduced by senescence

Heaviest Satcom: Inmarsat's Business Propelled to New Heights by Extra Aerojet Solid Motors on Atlas V

NASA Technical Reports Server (NTRS)

Covault, Craig

2005-01-01

The first EADS/Astrium Inmarsat 4, the largest commercial communications satellite ever launched, has completed four maneuvers to reach geosynchronous orbit where it has deployed its 30 X 40-ft. elliptical reflector and solar arrays spanning 148 ft. The 13,183-1b. spacecraft was launched Mar. 11 from Cape Canavera1 on the most powerful version to date of the Lockheed Martin International Launch Services (ILS) Atlas V.

Department of the Army Justification of Estimates for Fiscal Year 1983 Submitted to Congress February 1982. Part 5 (Other), Part 6 (National Guard Equipment) and Part 7 (PEMA).

DTIC Science & Technology

1982-02-01

JUST1ICTIOI OFI ZB URSM The major cat"ories of vhI"es Included im the request ms Tactical Veicles - $1039.7 miim for dolly so, trailers. smitrala e ead trucks...will provide a hybrid analog and Oigital capability to support the transition to the future systems. The program provides for automated operation

Delay-Doppler Radar Imaging

DTIC Science & Technology

1986-11-30

fwkhmn- 2 I rman = fwjhmr/confac sign-sq = sigmar * sigmar t- 0* t d ;1’r 0 1PI (t ype .eq. 0) THEN wjr i t e t tou t,2 0 r-ead (ttin, 10) twod im le::ttou...confac ":" = S gma.e*si gmae * c = s.._--i.mab*s i gmab _=.::os. .eq. 1) THEN Z, = .sigmab/ sigmar )/(2*pix) 1 C.8*xi2 END I F ,9 0 i = , mgdmt DO ??5 J

Two compounds in bed bug feces are sufficient to elicit off-host aggregation by bed bugs, Cimex lectularius.

PubMed

Olson, Joelle F; Vers, Leonard M Ver; Moon, Roger D; Kells, Stephen A

2017-01-01

After feeding, bed bugs aggregate in cracks and crevices near a host. Aggregation and arrestment are mediated by tactile and chemical stimuli associated with the bugs' feces and exuviae. Volatiles derived from fecally stained filter papers were analyzed by solid-phase microextraction (SPME) and evaluated using a multichoice behavioral assay to determine their impact on bed bug aggregation. In addition, crude fecal extracts were collected in methanol, analyzed by gas chromatography coupled with electroantennogram detection (GC-EAD) and mass spectrometry (GC-MS) and evaluated in open-air multichoice behavioral assays. The SPME method was used to detect (E)-2-hexenal and (E)-2-octenal in heated bed bug feces. The presence of these two volatile components did not affect aggregation. Analysis of the crude fecal extracts revealed several semi-volatile nitrogenous compounds, a carboxylic acid and a sulfur-based compound. Adult antennae responded to compounds eluted from three regions of the crude extract using GC-EAD. A combination of two compounds, dimethyl trisulfide and methyldiethanolamine, resulted in aggregation responses equivalent to the original crude extract. Bed bug aggregation is mediated by semi-volatile compounds derived from fecal extracts, and two compounds are sufficient to elicit aggregation. The two compounds identified here could be used to enhance the effectiveness of insecticidal applications or improve monitoring techniques. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

Sequential detection of different antigens induced by Epstein-Barr virus and herpes simplex virus in the same Western blot by using dual antibody probes.

PubMed

Lin, J C; Pagano, J S

1986-08-01

A dual antibody probing technique that permitted a color-coded identification of polypeptides representing different classes of Epstein-Barr virus (EBV) antigens as well as differentiation of the polypeptides induced by different herpesviruses in the same Western blot was developed. When the nitrocellulose sheet was probed first with monoclonal antibody against EBV early antigen diffuse component (EA-D) and then stained with 4-chloro-1-naphthol, four polypeptides specific for EA-D were identified by purple bands. Subsequently, the same nitrocellulose sheet was reprobed with human serum containing antibodies against EBV early antigen, viral capsid antigen, and nuclear antigen and stained with 3,3'-diaminobenzidine. Several brown bands corresponding to early, viral capsid, and nuclear antigen polypeptides were detected. The dual antibody probing technique was used in an analysis to differentiate polypeptides resulting from either EBV or herpes simplex virus infection, either in cells infected by individual virus or in a cell line dually infected by both viruses. On the basis of different colored bands in different lanes of the same gel, 20 polypeptides with molecular weights ranging from 31,000 to 165,000 were identified as herpes simplex virus-specific proteins. These results suggested that the dual antibody probing technique may be applicable in clinical diagnosis for detecting antigens and antibodies derived from different pathogens.

Comprehensive characterisation of atmospheric aerosols in Budapest, Hungary: physicochemical properties of inorganic species

NASA Astrophysics Data System (ADS)

Salma, Imre; Maenhaut, Willy; Zemplén-Papp, Éva; Záray, Gyula

As part of an air pollution project in Budapest, aerosol samples were collected by stacked filter units and cascade impactors at an urban background site, two downtown sites, and within a road tunnel in field campaigns conducted in 1996, 1998 and 1999. Some criteria pollutants were also measured at one of the downtown sites. The aerosol samples were analysed by one or more of the following methods: instrumental neutron activation analysis, particle-induced X-ray emission analysis, a light reflection technique, gravimetry, thermal profiling carbon analysis and capillary electrophoresis. The quantities measured or derived include atmospheric concentrations of elements (from Na to U), of particulate matter, of black and elemental carbon, and total carbonaceous fraction, of some ionic species (e.g., nitrate and sulphate) in the fine ( <2 μm equivalent aerodynamic diameter, EAD) or in both coarse (10- 2 μm EAD) and fine size fractions, atmospheric concentrations of NO, NO 2, SO 2, CO and total suspended particulate matter, and meteorological parameters. The analytical results were used for characterisation of the concentration levels, elemental composition, time trends, enrichment of and relationships among the aerosol species in coarse and fine size fractions, for studying their fine-to-coarse concentration ratios, spatial and temporal variability, for determining detailed elemental mass size distributions, and for examining the extent of chemical mass closure.

An investigation of care-based vs. rule-based morality in frontotemporal dementia, Alzheimer's disease, and healthy controls.

PubMed

Carr, Andrew R; Paholpak, Pongsatorn; Daianu, Madelaine; Fong, Sylvia S; Mather, Michelle; Jimenez, Elvira E; Thompson, Paul; Mendez, Mario F

2015-11-01

Behavioral changes in dementia, especially behavioral variant frontotemporal dementia (bvFTD), may result in alterations in moral reasoning. Investigators have not clarified whether these alterations reflect differential impairment of care-based vs. rule-based moral behavior. This study investigated 18 bvFTD patients, 22 early onset Alzheimer's disease (eAD) patients, and 20 healthy age-matched controls on care-based and rule-based items from the Moral Behavioral Inventory and the Social Norms Questionnaire, neuropsychological measures, and magnetic resonance imaging (MRI) regions of interest. There were significant group differences with the bvFTD patients rating care-based morality transgressions less severely than the eAD group and rule-based moral behavioral transgressions more severely than controls. Across groups, higher care-based morality ratings correlated with phonemic fluency on neuropsychological tests, whereas higher rule-based morality ratings correlated with increased difficulty set-shifting and learning new rules to tasks. On neuroimaging, severe care-based reasoning correlated with cortical volume in right anterior temporal lobe, and rule-based reasoning correlated with decreased cortical volume in the right orbitofrontal cortex. Together, these findings suggest that frontotemporal disease decreases care-based morality and facilitates rule-based morality possibly from disturbed contextual abstraction and set-shifting. Future research can examine whether frontal lobe disorders and bvFTD result in a shift from empathic morality to the strong adherence to conventional rules. Published by Elsevier Ltd.

An Investigation of Care-Based vs. Rule-Based Morality in Frontotemporal Dementia, Alzheimer’s Disease, and Healthy Controls

PubMed Central

Carr, Andrew R.; Paholpak, Pongsatorn; Daianu, Madelaine; Fong, Sylvia S.; Mather, Michelle; Jimenez, Elvira E.; Thompson, Paul; Mendez, Mario F.

2015-01-01

Behavioral changes in dementia, especially behavioral variant frontotemporal dementia (bvFTD), may result in alterations in moral reasoning. Investigators have not clarified whether these alterations reflect differential impairment of care-based vs. rule-based moral behavior. This study investigated 18 bvFTD patients, 22 early onset Alzheimer’s disease (eAD) patients, and 20 healthy age-matched controls on care-based and rule-based items from the Moral Behavioral Inventory and the Social Norms Questionnaire, neuropsychological measures, and magnetic resonance imaging (MRI) regions of interest. There were significant group differences with the bvFTD patients rating care-based morality transgressions less severely than the eAD group and rule-based moral behavioral transgressions more severely than controls. Across groups, higher care-based morality ratings correlated with phonemic fluency on neuropsychological tests, whereas higher rule-based morality ratings correlated with increased difficulty set-shifting and learning new rules to tasks. On neuroimaging, severe care-based reasoning correlated with cortical volume in right anterior temporal lobe, and rule-based reasoning correlated with decreased cortical volume in the right orbitofrontal cortex. Together, these findings suggest that frontotemporal disease decreases care-based morality and facilitates rule-based morality possibly from disturbed contextual abstraction and set-shifting. Future research can examine whether frontal lobe disorders and bvFTD result in a shift from empathic morality to the strong adherence to conventional rules. PMID:26432341

THE NEW ONLINE METADATA EDITOR FOR GENERATING STRUCTURED METADATA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Devarakonda, Ranjeet; Shrestha, Biva; Palanisamy, Giri

Nobody is better suited to describe data than the scientist who created it. This description about a data is called Metadata. In general terms, Metadata represents the who, what, when, where, why and how of the dataset [1]. eXtensible Markup Language (XML) is the preferred output format for metadata, as it makes it portable and, more importantly, suitable for system discoverability. The newly developed ORNL Metadata Editor (OME) is a Web-based tool that allows users to create and maintain XML files containing key information, or metadata, about the research. Metadata include information about the specific projects, parameters, time periods, andmore » locations associated with the data. Such information helps put the research findings in context. In addition, the metadata produced using OME will allow other researchers to find these data via Metadata clearinghouses like Mercury [2][4]. OME is part of ORNL s Mercury software fleet [2][3]. It was jointly developed to support projects funded by the United States Geological Survey (USGS), U.S. Department of Energy (DOE), National Aeronautics and Space Administration (NASA) and National Oceanic and Atmospheric Administration (NOAA). OME s architecture provides a customizable interface to support project-specific requirements. Using this new architecture, the ORNL team developed OME instances for USGS s Core Science Analytics, Synthesis, and Libraries (CSAS&L), DOE s Next Generation Ecosystem Experiments (NGEE) and Atmospheric Radiation Measurement (ARM) Program, and the international Surface Ocean Carbon Dioxide ATlas (SOCAT). Researchers simply use the ORNL Metadata Editor to enter relevant metadata into a Web-based form. From the information on the form, the Metadata Editor can create an XML file on the server that the editor is installed or to the user s personal computer. Researchers can also use the ORNL Metadata Editor to modify existing XML metadata files. As an example, an NGEE Arctic scientist use OME to register their datasets to the NGEE data archive and allows the NGEE archive to publish these datasets via a data search portal (http://ngee.ornl.gov/data). These highly descriptive metadata created using OME allows the Archive to enable advanced data search options using keyword, geo-spatial, temporal and ontology filters. Similarly, ARM OME allows scientists or principal investigators (PIs) to submit their data products to the ARM data archive. How would OME help Big Data Centers like the Oak Ridge National Laboratory Distributed Active Archive Center (ORNL DAAC)? The ORNL DAAC is one of NASA s Earth Observing System Data and Information System (EOSDIS) data centers managed by the Earth Science Data and Information System (ESDIS) Project. The ORNL DAAC archives data produced by NASA's Terrestrial Ecology Program. The DAAC provides data and information relevant to biogeochemical dynamics, ecological data, and environmental processes, critical for understanding the dynamics relating to the biological, geological, and chemical components of the Earth's environment. Typically data produced, archived and analyzed is at a scale of multiple petabytes, which makes the discoverability of the data very challenging. Without proper metadata associated with the data, it is difficult to find the data you are looking for and equally difficult to use and understand the data. OME will allow data centers like the NGEE and ORNL DAAC to produce meaningful, high quality, standards-based, descriptive information about their data products in-turn helping with the data discoverability and interoperability. Useful Links: USGS OME: http://mercury.ornl.gov/OME/ NGEE OME: http://ngee-arctic.ornl.gov/ngeemetadata/ ARM OME: http://archive2.ornl.gov/armome/ Contact: Ranjeet Devarakonda (devarakondar@ornl.gov) References: [1] Federal Geographic Data Committee. Content standard for digital geospatial metadata. Federal Geographic Data Committee, 1998. [2] Devarakonda, Ranjeet, et al. "Mercury: reusable metadata management, data discovery and access system." Earth Science Informatics 3.1-2 (2010): 87-94. [3] Wilson, B. E., Palanisamy, G., Devarakonda, R., Rhyne, B. T., Lindsley, C., & Green, J. (2010). Mercury Toolset for Spatiotemporal Metadata. [4] Pouchard, L. C., Branstetter, M. L., Cook, R. B., Devarakonda, R., Green, J., Palanisamy, G., ... & Noy, N. F. (2013). A Linked Science investigation: enhancing climate change data discovery with semantic technologies. Earth science informatics, 6(3), 175-185.« less

Cluster Ion Spectrometry (CIS) Data Archiving in the CAA

NASA Astrophysics Data System (ADS)

Dandouras, I. S.; Barthe, A.; Penou, E.; Brunato, S.; Reme, H.; Kistler, L. M.; Blagau, A.; Facsko, G.; Kronberg, E.; Laakso, H. E.

2009-12-01

The Cluster Active Archive (CAA) aims at preserving the four Cluster spacecraft data, so that they are usable in the long-term by the scientific community as well as by the instrument team PIs and Co-Is. This implies that the data are filed together with the descriptive and documentary elements making it possible to select and interpret them. The CIS (Cluster Ion Spectrometry) experiment is a comprehensive ionic plasma spectrometry package onboard the four Cluster spacecraft, capable of obtaining full three-dimensional ion distributions (about 0 to 40 keV/e) with a time resolution of one spacecraft spin (4 sec) and with mass-per-charge composition determination. The CIS package consists of two different instruments, a Hot Ion Analyser (HIA) and a time-of-flight ion Composition Distribution Function (CODIF) analyser. For the archival of the CIS data a multi-level approach has been adopted. The CAA archival includes processed raw data (Level 1 data), moments of the ion distribution functions (Level 2 data), and calibrated high-resolution data in a variety of physical units (Level 3 data). The latter are 3-D ion distribution functions and 2-D pitch-angle distributions. In addition, a software package has been developed to allow the CAA user to interactively calculate partial or total moments of the ion distributions. Instrument cross-calibration has been an important activity in preparing the data for archival. The CIS data archive includes also experiment documentation, graphical products for browsing through the data, and data caveats. In addition, data quality indexes are under preparation, to help the user. Given the complexity of an ion spectrometer, and the variety of its operational modes, each one being optimised for a different magnetospheric region or measurement objective, consultation of the data caveats by the end user will always be a necessary step in the data analysis.

Between Oais and Agile a Dynamic Data Management Approach

NASA Astrophysics Data System (ADS)

Bennett, V. L.; Conway, E. A.; Waterfall, A. M.; Pepler, S.

2015-12-01

In this paper we decribe an approach to the integration of existing archival activities which lies between compliance with the more rigid OAIS/TRAC standards and a more flexible "Agile" approach to the curation and preservation of Earth Observation data. We provide a high level overview of existing practice and discuss how these procedures can be extended and supported through the description of preservation state. The aim of which is to facilitate the dynamic controlled management of scientific data through its lifecycle. While processes are considered they are not statically defined but rather driven by human interactions in the form of risk management/review procedure that produce actionable plans, which are responsive to change. We then proceed by describing the feasibility testing of extended risk management and planning procedures which integrate current practices. This was done through the CEDA Archival Format Audit which inspected British Atmospheric Data Centre and NERC Earth Observation Data Centre Archival holdings. These holdings are extensive, comprising of around 2 Petabytes of data and 137 million individual files, which were analysed and characterised in terms of format, based risk. We are then able to present an overview of the format based risk burden faced by a large scale archive attempting to maintain the usability of heterogeneous environmental data sets We continue by presenting a dynamic data management information model and provide discussion of the following core model entities and their relationships: Aspirational entities, which include Data Entity definitions and their associated Preservation Objectives. Risk entities, which act as drivers for change within the data lifecycle. These include Acquisitional Risks, Technical Risks, Strategic Risks and External Risks Plan entities, which detail the actions to bring about change within an archive. These include Acquisition Plans, Preservation Plans and Monitoring plans which support responsive interactions with the community. The Result entities describe the outcomes of the plans. This includes Acquisitions. Mitigations and Accepted Risks. With risk acceptance permitting imperfect but functional solutions that can be realistically supported within an archives resource levels

Anti-Epstein-Barr virus antibodies in Beijing during 2013-2017: What we have found in the different patients.

PubMed

Cui, Jingtao; Yan, Wenjuan; Xu, Shaoxia; Wang, Qiaofeng; Zhang, Weihong; Liu, Wenjing; Ni, Anping

2018-01-01

Epstein-Barr virus (EBV) is associated with nasopharyngeal carcinoma (NPC) which is prevalent in South China, and its association with systemic lupus erythematosus (SLE) or other autoimmune diseases has not been studied in the mainland of China. The EBV serological tests have been performed on patients with various diseases or manifestations for years at our institution and their values need to be evaluated. For routine medical purposes, anti-EB viral capsid antigen (VCA) IgG, IgA and IgM antibodies, anti-EBV diffuse early antigen (EA-D) IgA antibodies, and anti-EBV nuclear antigen-1(EBNA-1) IgG antibodies were tested with commercial enzyme-linked immunosorbent assay (ELISA) in patients visiting Peking Union Medical College Hospital between 2013 and 2017. The test results were analyzed in this retrospective study. There were a total of 11122 serum samples available to be tested in the study. As indicators of past EBV infection, the prevalence of VCA-IgG/EBNA1-IgG were 66.6%/58.5%, 84.3%/78.8%, 92.9%/87.0% and 98.5%/95.4% in patients aged under 5 years, 6-10 years, 11-20 years and 21-30 years old, respectively, and these values maintained at this highest rate as age increased further. The prevalence of VCA-IgM, as a parameter of acute EBV infection, was 14.6%, 10.2%, 10.4%, 6.3% and 3.1% in patients aged under 5 years, 6-10 years,11-20 years, 21-30 years, 31-40 years old, respectively, and decreased to 2%~3% in older patients. Patients with elevated serum liver enzymes were more likely to have a higher prevalence of EA/D IgA antibody (P < 0.01) and young patients (≤30 years) with lymphadenopathy were more likely to have higher prevalence of VCA-IgM antibody (P < 0.01). The prevalence of VCA-IgA and EAD-IgA were 87.0% and 59.2% in NPC patients, respectively, and both were significantly higher (P < 0.001) than that in non-NPC patients. The prevalence of VCA-IgA was 45.4% and 25.6% in SLE patients and patients with other autoimmune diseases, respectively, which were significantly (P < 0.001) and mildly (P = 0.039) higher than their controls. In pediatric SLE patients between 6 and10 years old, the prevalence of VCA-IgG, VCA-IgA and EBNA1-IgG was 100%, 59.5% and 100%, respectively, all being significantly higher than the age (6-10y) related controls (P< 0.01). In the 705 cerebral spinal fluid (CSF) specimens, VCA-IgG, VCA-IgM, VCA-IgA and EAD-IgA were found to be positive in 12.1%, 0.15%, 0.25% and 0.25%, respectively. There were 157 paired specimens (CSF and serum were collected simultaneously) and VCA-IgG was identified as positive in 12.7% of the CSF and 100% of the serum specimens. Around 98% of Chinese patients were infected with EBV before 30 years of age and the highest rate of acute EBV infection were observed in patients under 5 years old. EBV infection was found to be associated with elevated serum liver enzymes, NPC and SLE. Acute anti-EBV antibody was valued for young patients with lymphadenopathy but limited value for CNS neuropathy.

ARCUS Internet Media Archive (IMA): A Window into the Arctic - An Online Resource For Education and Outreach

NASA Astrophysics Data System (ADS)

Buxbaum, T. M.; Warnick, W. K.; Polly, B.; Breen, K. J.

2007-12-01

The ARCUS Internet Media Archive (IMA) is a collection of photos, graphics, videos, and presentations about the Arctic and Antarctic that are shared through the Internet. It provides the polar research community and the public at large with a centralized location where images and video pertaining to polar research can be browsed and retrieved for a variety of uses. The IMA currently contains almost 6,500 publicly accessible photos, including 4,000 photos from the National Science Foundation (NSF) funded Teachers and Researchers Exploring and Collaborating (TREC) program, an educational research experience in which K-12 teachers participate in arctic research as a pathway to improving science education. The IMA is also the future home of all electronic media from the NSF funded PolarTREC program, a continuation of TREC that now takes place in both the Arctic and Antarctic. The IMA includes 450 video files, 270 audio files, nearly 100 graphics and logos, 28 presentations, and approximately 10,000 additional resources that are being prepared for public access. The contents of this archive are organized by file type, photographer's name, event, or by organization, with each photo or file accompanied by information on content, contributor source, and usage requirements. All the files are keyworded and all information, including file name and description, is completely searchable. ARCUS plans to continue to improve and expand the IMA with a particular focus on providing graphics depicting key arctic research results and findings as well as edited video archives of relevant scientific community meetings. To submit files or for more information and to view the ARCUS Internet Media Archive, please go to: http://media.arcus.org or email photo@arcus.org.

Superfund Public Information System (SPIS), January 1999

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1999-01-01

The Superfund Public Information System (SPIS) on CD-ROM contains Superfund data for the United States Environmental Protection Agency. The Superfund data is a collection of three databases: Records of Decision (RODS); Comprehensive Environmental, Response, Compensation, and Liability Information System (CERCLIS); and Archive (NFRAP). Descriptions of these databases and CD contents are listed below. Data content: The CD contains the complete text of the official ROD documents signed and issued by EPA from fiscal years 1982--1996; 147 RODs for fiscal year 1997; and seven RODs for fiscal year 1998. The CD also contains 89 Explanation of Significant Difference (ESD) documents, asmore » well as 48 ROD Amendments. CERCLIS and Archive (NFRAP) data is through January 19, 1999. RODS is the Records Of Decision System. RODS is used to track site clean-ups under the Superfund program to justify the type of treatment chosen at each site. RODS contains information on technology justification, site history, community participation, enforcement activities, site characteristics, scope and role of response action, and remedy. Explanation of Significant Differences (ESDs) are also available on the CD. CERCLIS is the Comprehensive Environmental Response, Compensation, and Liability Information System. It is the official repository for all Superfund site and incident data. It contains comprehensive information on hazardous waste sites, site inspections, preliminary assessments, and remedial status. The system is sponsored by the EPA`s Office of Emergency and Remedial Response, Information Management Center. Archive (NFRAP) consists of hazardous waste sites that have no further remedial action planned; only basic identifying information is provided for archive sites. The sites found in the Archive database were originally in the CERCLIS database, but were removed beginning in the fall of 1995.« less

SPINS: standardized protein NMR storage. A data dictionary and object-oriented relational database for archiving protein NMR spectra.

PubMed

Baran, Michael C; Moseley, Hunter N B; Sahota, Gurmukh; Montelione, Gaetano T

2002-10-01

Modern protein NMR spectroscopy laboratories have a rapidly growing need for an easily queried local archival system of raw experimental NMR datasets. SPINS (Standardized ProteIn Nmr Storage) is an object-oriented relational database that provides facilities for high-volume NMR data archival, organization of analyses, and dissemination of results to the public domain by automatic preparation of the header files required for submission of data to the BioMagResBank (BMRB). The current version of SPINS coordinates the process from data collection to BMRB deposition of raw NMR data by standardizing and integrating the storage and retrieval of these data in a local laboratory file system. Additional facilities include a data mining query tool, graphical database administration tools, and a NMRStar v2. 1.1 file generator. SPINS also includes a user-friendly internet-based graphical user interface, which is optionally integrated with Varian VNMR NMR data collection software. This paper provides an overview of the data model underlying the SPINS database system, a description of its implementation in Oracle, and an outline of future plans for the SPINS project.

Global data bases on distribution, characteristics and methane emission of natural wetlands: Documentation of archived data tape

NASA Technical Reports Server (NTRS)

Matthews, Elaine

1989-01-01

Global digital data bases on the distribution and environmental characteristics of natural wetlands, compiled by Matthews and Fung (1987), were archived for public use. These data bases were developed to evaluate the role of wetlands in the annual emission of methane from terrestrial sources. Five global 1 deg latitude by 1 deg longitude arrays are included on the archived tape. The arrays are: (1) wetland data source, (2) wetland type, (3) fractional inundation, (4) vegetation type, and (5) soil type. The first three data bases on wetland locations were published by Matthews and Fung (1987). The last two arrays contain ancillary information about these wetland locations: vegetation type is from the data of Matthews (1983) and soil type from the data of Zobler (1986). Users should consult original publications for complete discussion of the data bases. This short paper is designed only to document the tape, and briefly explain the data sets and their initial application to estimating the annual emission of methane from natural wetlands. Included is information about array characteristics such as dimensions, read formats, record lengths, blocksizes and value ranges, and descriptions and translation tables for the individual data bases.

Half-century archives of occupational medical data on French nuclear workers: a dusty warehouse or gold mine for epidemiological research?

PubMed

Garsi, Jerome-Philippe; Samson, Eric; Chablais, Laetitia; Zhivin, Sergey; Niogret, Christine; Laurier, Dominique; Guseva Canu, Irina

2014-12-01

This article discusses the availability and completeness of medical data on workers from the AREVA NC Pierrelatte nuclear plant and their possible use in epidemiological research on cardiovascular and metabolic disorders related to internal exposure to uranium. We created a computer database from files on 394 eligible workers included in an ongoing nested case-control study from a larger cohort of 2897 French nuclear workers. For each worker, we collected records of previous employment, job positions, job descriptions, medical visits, and blood test results from medical history. The dataset counts 9,471 medical examinations and 12,735 blood test results. For almost all of the parameters relevant for research on cardiovascular risk, data completeness and availability is over 90%, but it varies with time and improves in the latest time period. In the absence of biobanks, collecting and computerising available good-quality occupational medicine archive data constitutes a valuable alternative for epidemiological and aetiological research in occupational health. Biobanks rarely contain biological samples over an entire worker's carrier and medical data from nuclear industry archives might make up for unavailable biomarkers that could provide information on cardiovascular and metabolic diseases.

Recent developments of advanced structures for space optics at Astrium, Germany

NASA Astrophysics Data System (ADS)

Stute, Thomas; Wulz, Georg; Scheulen, Dietmar

2003-12-01

The mechanical division of EADS Astrium GmbH, Friedrichshafen Germany, the former Dornier Satellitensystem GmbH is currently engaged with the development, manufacturing and testing of three different advanced dimensionally stable composite and ceramic material structures for satellite borne optics: -CFRP Camera Structure -Planck Telescope Reflectors -NIRSpec Optical Bench Breadboard for James Web Space Telescope The paper gives an overview over the requirements and the main structural features how these requirements are met. Special production aspects and available test results are reported.

Temporal Evolution of the LIBS Spectrum of Aluminum Metal in Different Bath Gases

DTIC Science & Technology

2004-12-01

emission from . A lens was pl e ter (Catalina Scientific Corp., Tucson, AZ) fitted with a gated mera echnology Com., Model D 8-03) was used to m...Single Pulse Laser Ablati 1999 Amoruso, S. Modeling of UV-Pulsed Laser Ablation of Silicon. Appl. Phys. A 1999, 69 323. 17. Saramdaev, E. V...TR CODE ST D 20640-5035 R BLDG 600 MD 20640-5035 FARE CTR R GUIRGUIS EAD MD 20640-5035 E WARFARE CTR LOGY DEPT J HARPER 640

Space Shuttle Main Engine structural analysis and data reduction/evaluation. Volume 3A: High pressure oxidizer turbo-pump preburner pump housing stress analysis report

NASA Technical Reports Server (NTRS)

Shannon, Robert V., Jr.

1989-01-01

The model generation and structural analysis performed for the High Pressure Oxidizer Turbopump (HPOTP) preburner pump volute housing located on the main pump end of the HPOTP in the space shuttle main engine are summarized. An ANSYS finite element model of the volute housing was built and executed. A static structural analysis was performed on the Engineering Analysis and Data System (EADS) Cray-XMP supercomputer

Contributions to the Data on Theoretical Metallurgy. 3. The Free Energies of Vaporization and Vapor Pressures of Inorganic Substances

DTIC Science & Technology

1935-01-01

109ead-------------59 Vapor-pressure table ----------- 110 Lithium -------------------- 63 Bibliography ----------------- 115 Acceson orj NYTIS CRAMI ti...852-926*) have measured the vapor pressure of lithium in the liquid state, and Ruff and Jobannsen (32~4) have stated that the boili point is above...the results of th~e three investigations on ii u{id lithium do not agree, some arbitrar choice must be made. V this case, the data of Hartmann and

Market Dominance, Efficiency, Innovation, and Globalization: A Case Study of the Tanker Competition Between Boeing and Northrop Grumman/EADS

DTIC Science & Technology

2008-04-23

corporate practices in the post- Enron world, to more up-to- date and open government procurement practices. These trends have resulted in the coalescence of...significant risks to the global community • Shift toward more transparent processes both in corporate practices in the post- Enron world and in government ...is losing its traditional edge; and (d) the desire to have an open and fair government procurement process in which all parties are able to

Design, Development and Validation of the Eurostar 3000 Large Propellant Tank

NASA Astrophysics Data System (ADS)

Autric, J.-M.; Catherall, D.; Figues, C.; Brockhoff, T.; Lafranconi, R.

2004-10-01

EADS Astrium has undertaken the design and development of an enlarged propellant tank for its high modular Eurostar 3000 telecom satellites platform. The design and development activities included fracture, stress and functional analysis, the manufacturing of development models for the propellant management device, the qualification of new manufacturing processes and the optimization of the design with respect to the main requirements. The successful design and development-testing phase has allowed starting the manufacturing of the qualification model.

The Coast Artillery Journal. Volume 91, Number 4, July-August 1948

DTIC Science & Technology

1948-08-01

The development of completely automatic control systems was suspended in 1945 because of the critical manpower shortage and scarcity of materials...the three years I spent o\\’erseas. During the fall of 1942, a few weeks before the im’asion of Africa, the armv assembled in Fort 1\\1eade about sixty...from June 1945 to April 1947. University af Washington: James E. l\\laran of Centralia, \\,vashington. Cadet Moran is majoring in History . During the war

Surfacing Rescue Container Concept Design for Trident Submarines

DTIC Science & Technology

2009-05-08

crew of their decompression obligation and will give undersea medical officers (UMO) on land the information they need to treat the crew upon arrival...ard . B ead boa ) Ba wit to ntly ora sa en s o is d OX ld er s h ule los is e v of t . L ec pu tin tte hin ad a te fety den f s to ma t...Technical Information Service, 1970. [34] SURVIVEX 2003, Exercise Tests Disabled Submarine Survival. Horn, Wayne G. 1, s.l. : Undersea Warfare

An Expansion of Glider Observation STrategies to Systematically Transmit and Analyze Preferred Waypoints of Underwater Gliders

DTIC Science & Technology

2015-01-01

exercis ead over time i e rendezvous C function. nformation ne that set of po antify the relat are combined to as a morpho runs independ rs. EMPath a...Glider pilots do not use the temporal waypoint estimate from GOST in their control of the glider; waypoints are simply treated as a sequence of points...glider pilots’ interpretation of points as only sequential instead of temporal will eliminate this as a hindrance to the system’s use. Further

Re-entry Flight Experiments Lessons Learned - The Atmospheric Reentry Demonstrator ARD

DTIC Science & Technology

2007-06-01

civilian cooperative program was managed by Aerospatiale – Lanceurs Stratégiques et Spatiaux (now EADS – SPACE Transportation) as prime contractor. The...of an Al-alloy structure protected on the cone by Norcoat 62250 FI cork tiles and on the heat-shield by Aleastrasil silica-phenolic tiles (Figure 3... structure of the flight data points are meaningful even if the absolute Kp level is doubtful. Figure 19 shows CFD comparisons at Mach 10. The real gas

Antecedents and Consequences of Choice.

DTIC Science & Technology

1981-04-01

ADAO97 738 VIRGINIA POLYTECHNIC INST AND STATE UNIV BLACKSBURG F/A 5/10I -A077 ANTECEDENTS AND CONSEQUENCES OF CHOICE.(U) A PR 81 L C PERIMUTER...1. REOR W ..... T ATO PAGE EAD iNSTRUCTiONS 4. TITL. , O PC OF REPORT A PERIOD COVERED( Antecedents and Consequences of Choic Final rN t 7. NTR,_C...sense of control has motivational consequences which may enhance performance on a variety of tasks .lost researchers in this field recognize that the

BKCASE(TM) Body of Knowledge and Curriculum to Advance Systems Engineering

DTIC Science & Technology

2010-04-28

Lawson, Lawson Konsult AB, Sweden Johann Amsenga, Eclipse RDC, South Africa Alex Lee , Defence Science and Technology Agency, Singapore Erik Aslaksen...Engineering Division, US Tim Ferris, University of South Australia and INCOSE, Australia Jean-Claude Roussel, EADS, France Kevin Forsberg, Center for...Systems Management and INCOSE, US Sven-Olaf Schulze, Berner & Mattner Systemtechnik GmbH, Germany Richard Freeman, Air Force Center for Systems

Navy Quality of Life and Reenlistment.

DTIC Science & Technology

1981-11-01

Problema with Unique Solution,- 20 pp., Jun 1976, 234-253) AD AOSS 536 AD AO SYSpp 223 pp 213 Mengel . Marc. *StOdetlc Mechanics of Moleoloion thloule... Mengel . Marc. ’Fluctuations In Systeme with Multiple Steady lesecttons.’ 21 pp.. Jan 1978. AD AD%6 227 Stetes. Application to Landmaster Equations,’ 12 pp...Qirrot Mengel , bee ead QuenAw*, Gould D.. ’Ilop aleam of a 0Ias~ Facing oer movet and Busanss Learsa presented by Slverlsto Normal Oe as Offet CIrcle

Less is More: Pooling and Sharing of European Military Capabilities in the Past and Present

DTIC Science & Technology

2012-06-01

defense of allied countries are interests, among others, that should be protected.” Jacques Chirac, speech at Landivisiau-l’Ile Longue/ Brest , 19...in the EU’s Common Security and Defence Policy (CSDP) is a comfortable situation that allows Paris to rely on the Franco-German leadership...management jobs from Germany to France. He publicly demanded that „In all current reorganization of EADS, we should stick to the original idea: a fair

The human-induced pluripotent stem cell initiative-data resources for cellular genetics.

PubMed

Streeter, Ian; Harrison, Peter W; Faulconbridge, Adam; Flicek, Paul; Parkinson, Helen; Clarke, Laura

2017-01-04

The Human Induced Pluripotent Stem Cell Initiative (HipSci) isf establishing a large catalogue of human iPSC lines, arguably the most well characterized collection to date. The HipSci portal enables researchers to choose the right cell line for their experiment, and makes HipSci's rich catalogue of assay data easy to discover and reuse. Each cell line has genomic, transcriptomic, proteomic and cellular phenotyping data. Data are deposited in the appropriate EMBL-EBI archives, including the European Nucleotide Archive (ENA), European Genome-phenome Archive (EGA), ArrayExpress and PRoteomics IDEntifications (PRIDE) databases. The project will make 500 cell lines from healthy individuals, and from 150 patients with rare genetic diseases; these will be available through the European Collection of Authenticated Cell Cultures (ECACC). As of August 2016, 238 cell lines are available for purchase. Project data is presented through the HipSci data portal (http://www.hipsci.org/lines) and is downloadable from the associated FTP site (ftp://ftp.hipsci.ebi.ac.uk/vol1/ftp). The data portal presents a summary matrix of the HipSci cell lines, showing available data types. Each line has its own page containing descriptive metadata, quality information, and links to archived assay data. Analysis results are also available in a Track Hub, allowing visualization in the context of public genomic annotations (http://www.hipsci.org/data/trackhubs). © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

ILRS Website Update

NASA Technical Reports Server (NTRS)

Noll, Carey E.; Torrence, Mark H.; Pollack, Nathan H.; Tyahla, Lori J.

2013-01-01

The ILRS website, http://ilrs.gsfc.nasa.gov, is the central source of information for all aspects of the service. The website provides information on the organization and operation of the ILRS and descriptions of ILRS components data, and products. Furthermore, the website provides an entry point to the archive of these data products available through the data centers. Links are provided to extensive information on the ILRS network stations including performance assesments and data quality evaluations. Descriptions of suported satellite missions (current, future, and past) are provided to aid in station acquisition and data analysis. The website was reently redesigned. Content was reviewed during the update process, ensuring information is current and useful. This poster will provide specific examples of key sections, applicaitons, and webpages.

The archives of the glacier survey of the Austrian Alpine Club

NASA Astrophysics Data System (ADS)

Fischer, Andrea; Bendler, Gebhard

2016-04-01

The archive of the Austrian Alpine Club holds masses of material on glaciers and their former extent. The material includes descriptions and sketches of the summits conquered by early mountaineers, mapping campaigns and data from early scientific expeditions as well as data on glacier length change. To date a large proportion of the glaciological information in the material has not been catalogued or analysed. As cold ice, containing relevant climate information, might still exist at the highest peaks of Austria, a pilot project was started to collect some of the data of two test sites in Tyrol, in Silvretta and Ötztal Alps, to reveal former summit shapes and glacier tongue positions. Additional information on the number and position of crevasses as well as firn extent is often evident from the material. Challenging tasks not yet tackled are compiling a catalogue of the material and defining an analysis scheme.

PsychVACS: a system for asynchronous telepsychiatry.

PubMed

Odor, Alberto; Yellowlees, Peter; Hilty, Donald; Parish, Michelle Burke; Nafiz, Najia; Iosif, Ana-Maria

2011-05-01

To describe the technical development of an asynchronous telepsychiatry application, the Psychiatric Video Archiving and Communication System. A client-server application was developed in Visual Basic.Net with Microsoft(®) SQL database as the backend. It includes the capability of storing video-recorded psychiatric interviews and manages the workflow of the system with automated messaging. Psychiatric Video Archiving and Communication System has been used to conduct the first ever series of asynchronous telepsychiatry consultations worldwide. A review of the software application and the process as part of this project has led to a number of improvements that are being implemented in the next version, which is being written in Java. This is the first description of the use of video recorded data in an asynchronous telemedicine application. Primary care providers and consulting psychiatrists have found it easy to work with and a valuable resource to increase the availability of psychiatric consultation in remote rural locations.

Thermonuclear Propaganda: Presentations of Nuclear Strategy in the Early Atomic Age

DTIC Science & Technology

2014-06-01

comics .17 One scholar of atomic culture noted the ambiguity of the duality of the atomic age as a central tenant to building the “most powerful of all...2004). 18 Ferenc Morton Szasz, Atomic Comics : Cartoonists Confront the Nuclear World (Reno, NV: University of Nevada Press, 2012), 135. 19 Ibid...research.archives.gov/description/36952. 28 Osgood, Total Cold War; Szasz, Atomic Comics ; Zeman and Amundson, Atomic Culture, 3-4. 10 the most modern

Olfactory response of Anastrepha striata (Diptera: Tephritidae) to guava and sweet orange volatiles.

PubMed

Diaz-Santiz, Edvin; Rojas, Julio C; Cruz-López, Leopoldo; Hernández, Emilio; Malo, Edi A

2016-10-01

The behavioral responses of virgin and mated female Anastrepha striata Schiner (Diptera: Tephritidae) to guava (Psidium guajava L.) or sweet orange (Citrus sinensis L.) were evaluated separately using multilure traps in two-choice tests in field cages. The results showed that flies were more attracted to guava and sweet orange volatiles than to control (unbaited trap). The physiological state (virgin or mated) of females did not affect their attraction to the fruit volatiles. Combined analysis of gas chromatography coupled with electroantennography (GC-EAD) of volatile extracts of both fruits showed that 1 and 6 compounds from orange and guava, respectively elicited repeatable antennal responses from mated females. The EAD active compounds in guava volatile extracts were identified by gas chromatography-mass spectrometry (GC-MS) as ethyl butyrate, (Z)-3-hexenol, hexanol, ethyl hexanoate, hexyl acetate, and ethyl octanoate. Linalool was identified as the only antennal active compound in sweet orange extracts. In field cage tests, there were no significant differences between the number of mated flies captured by the traps baited with guava extracts and the number caught by traps baited with the 6-component blend that was formulated according to the relative proportions in the guava extracts. Similar results occurred when synthetic linalool was evaluated against orange extracts. From a practical point of view, the compounds identified in this study could be used for monitoring A. striata populations. © 2015 Institute of Zoology, Chinese Academy of Sciences.

Focal plane AIT sequence: evolution from HRG-Spot 5 to Pleiades HR

NASA Astrophysics Data System (ADS)

Le Goff, Roland; Pranyies, Pascal; Toubhans, Isabelle

2017-11-01

Optical and geometrical image qualities of Focal Planes, for "push-broom" high resolution remote sensing satellites, require the implementation of specific means and methods for the AIT sequence. Indeed the geometric performances of the focal plane mainly axial focusing and transverse registration, are duly obtained on the basis of adjustment, setting and measurement of optical and CCD components with an accuracy of a few microns. Since the end of the 1970s, EADS-SODERN has developed a series of detection units for earth observation instruments like SPOT and Helios. And EADS-SODERN is now responsible for the development of the Pleiades High Resolution Focal Plane assembly. This paper presents the AIT sequences. We introduce all the efforts, innovative solutions and improvements made on the assembly facilities to match the technical evolutions and breakthrough of the Pleiades HR FP concept in comparison with the previous High Resolution Geometric SPOT 5 Focal Plane. The main evolution drivers are the implementation of strip filters and the realization of 400 mm continuous retinas. For Pleiades HR AIT sequence, three specific integration and measuring benches, corresponding with the different assembly stages, are used: a 3-D non-contact measurement machine for the assembly of detection module, a 3-D measurement machine for mirror integration on the main Focal Plane SiC structure, and a 3-D geometric coordinates control bench to focus detection module lines and to ensure they are well registered together.

Interrelationships Between Aerosol Characteristics and Light Scattering During Late-winter in a Eastern Mediterranean Arid Environment

NASA Technical Reports Server (NTRS)

Ichoku, C.; Andreae, M. O.; Meixner, F. X.; Schebeske, G.; Formenti, P.; Maenhaut, W.; Cafmeyer, J.; Ptasinski, J.; Karnieli, A.; Orlovsky, L.

1999-01-01

An intensive field campaign involving measurement of various aerosol physical, chemical, and radiative properties was conducted at Sde Boker in the Negev Desert of Israel, from 18 February to 15 March 1997. Nephelometer measurements gave average background scattering coefficient values of about 25 M/m at 550 nm wavelength, but strong dust events caused the value of this parameter to rise up to about 800 M/m Backscattering fractions did not depend on aerosol loading, and generally fell in the range of 0.1 to 0.25, comparable to values reported for marine and Arctic environments. Chemical analysis of the aerosol revealed that, in the coarse size range (2 - 10 micrometer equivalent aerodynamic diameter (EAD)), calcium (Ca) was by far the most abundant element followed by silicon (Si), both of which are indicators for mineral dust. In the fine size fraction (< 2 micrometers EAD), sulfur (S) generally was the dominant element, except during high dust episodes when Ca and Si were again the most abundant. Furthermore, fine black carbon (BC) correlates with S, suggesting that they may have originated from the same sources or source regions. An indication of the short-term effect of aerosol loading on radiative forcing was provided by measurements of global and diffuse solar radiation, which showed that during high turbidity periods (strong dust events) almost all of the solar radiation reaching the area is scattered or absorbed.

Interrelationships between aerosol characteristics and light scattering during late winter in an Eastern Mediterranean arid environment

NASA Astrophysics Data System (ADS)

Ichoku, Charles; Andreae, Meinrat O.; Andreae, Tracey W.; Meixner, Franz X.; Schebeske, Guenther; Formenti, Paola; Maenhaut, Willy; Cafmeyer, Jan; Ptasinski, Jacek; Karnieli, Arnon; Orlovsky, Leah

1999-10-01

An intensive field campaign involving measurement of various aerosol physical, chemical, and radiative properties was conducted at Sde Boker (also written as Sede Boqer) in the Negev Desert of Israel, from 18 February to 15 March 1997. Nephelometer measurements gave average background scattering coefficient values of about 25 Mm-1 at 550 nm wavelength, but strong dust events caused the value of this parameter to rise up to about 800 Mm-1. Backscattering fractions did not depend on aerosol loading and generally fell in the range of 0.1 to 0.25, comparable to values reported for marine and Arctic environments. Chemical analysis of the aerosol revealed that in the coarse size range (2-10 μm equivalent aerodynamic diameter (EAD)), calcium (Ca) was by far the most abundant element followed by silicon (Si), both of which are indicators for mineral dust. In the fine size fraction (<2 μm EAD), sulfur (S) generally was the dominant element, except during high dust episodes when Ca and Si were again the most abundant. Furthermore, fine black carbon (BC) correlates with S, suggesting that they may have originated from the same sources or source regions. An indication of the short-term effect of aerosol loading on radiative forcing was provided by measurements of global and diffuse solar radiation, which showed that during high-turbidity periods (strong dust events), almost all of the solar radiation reaching the area is scattered or absorbed.

Distinct gene-specific mechanisms of arrhythmia revealed by cardiac gene transfer of two long QT disease genes, HERG and KCNE1.

PubMed

Hoppe, U C; Marbán, E; Johns, D C

2001-04-24

The long QT syndrome (LQTS) is a heritable disorder that predisposes to sudden cardiac death. LQTS is caused by mutations in ion channel genes including HERG and KCNE1, but the precise mechanisms remain unclear. To clarify this situation we injected adenoviral vectors expressing wild-type or LQT mutants of HERG and KCNE1 into guinea pig myocardium. End points at 48-72 h included electrophysiology in isolated myocytes and electrocardiography in vivo. HERG increased the rapid component, I(Kr), of the delayed rectifier current, thereby accelerating repolarization, increasing refractoriness, and diminishing beat-to-beat action potential variability. Conversely, HERG-G628S suppressed I(Kr) without significantly delaying repolarization. Nevertheless, HERG-G628S abbreviated refractoriness and increased beat-to-beat variability, leading to early afterdepolarizations (EADs). KCNE1 increased the slow component of the delayed rectifier, I(Ks), without clear phenotypic sequelae. In contrast, KCNE1-D76N suppressed I(Ks) and markedly slowed repolarization, leading to frequent EADs and electrocardiographic QT prolongation. Thus, the two genes predispose to sudden death by distinct mechanisms: the KCNE1 mutant flagrantly undermines cardiac repolarization, and HERG-G628S subtly facilitates the genesis and propagation of premature beats. Our ability to produce electrocardiographic long QT in vivo with a clinical KCNE1 mutation demonstrates the utility of somatic gene transfer in creating genotype-specific disease models.

Reusable Boosters in a European-Russian Perspective

NASA Astrophysics Data System (ADS)

Deneu, François; Ramiandrasoa, Fabienne

2002-01-01

In 2001, EADS and Khrunichev SRPSC have initiated and carried out a working group devoted to the analysis of potential common studies and developments in the field of space activities. This working group came up with several propositions of interest, among which, the use of reusable boosters issued from Khrunichev previous design appeared to be promising when applied to heavy type launchers. Although the results required to be confirmed by detailed studies prior to final conclusions, preliminary studies have shown the interest of Ariane 5 configurations using such reusable booster in view of reducing the specific and launch cost as well as potentially increasing the performance. In November 2001, EADS and KHRUNICHEV SRPSC have started a study on an Ariane 5 plus reusable boosters configuration. This study aims at obtaining a better understanding of the advantages and drawbacks attached to such a use. Technical feasibility is more in depth analysed, with all recurring and not recurring aspects (including launch infrastructure modifications). Programmatic aspects are also addressed in order to better assess potential economic advantages and unavoidable drawbacks. Beyond that the identification of what could be, for western Europe and Russian players, an efficient and pay- off industrial organisation, is also a study theme of importance. This papers intends to present the main results achieved within this study and the propositions for the future which are likely to provide western Europe and Russia with stronger positions in the competitive field of launch business.

Theory of Mind and social reserve: Alternative hypothesis of progressive Theory of Mind decay during different stages of Alzheimer's disease.

PubMed

Fliss, Rafika; Le Gall, Didier; Etcharry-Bouyx, Frédérique; Chauviré, Valérie; Desgranges, Béatrice; Allain, Philippe

2016-01-01

Although Theory of Mind (ToM) is thought to be impaired in Alzheimer's disease (AD), it remains unclear whether this impairment is linked to the level of task complexity, the heterogeneity of the studied patients, or the implication of executive dysfunctions. To elucidate this point, 42 AD patients, divided into two subgroups [moderate AD (mAD) patients (n = 19) and early AD (eAD) patients (n = 23)], and 23 matched healthy older subjects (HO) were enrolled. All participants were given (1) a false-belief task (cognitive ToM), (2) a revised version of the "Reading the Mind in the Eyes" test (affective ToM), and (3) a composite task designed to assess ToM abilities with minimal cognitive demands. Participants were also given executive tasks assessing inhibition, shifting, and updating processes. We observed a significant impairment of cognitive and composite ToM abilities in eAD patients compared with mAD patients. There was no impairment of affective ToM. Stepwise regression revealed that measures of global efficiency and executive functions (EFs) were the best predictors of progressive decay of ToM scores. These results indicate that cognitive aspects of ToM are more sensitive to AD progression than affective tasks. They also show that ToM abilities are more affected by dementia severity than by task complexity. One explanation of our results is the presence of compensatory mechanisms (social reserve) in AD.

Long-term Science Data Curation Using a Digital Object Model and Open-Source Frameworks

NASA Astrophysics Data System (ADS)

Pan, J.; Lenhardt, W.; Wilson, B. E.; Palanisamy, G.; Cook, R. B.

2010-12-01

Scientific digital content, including Earth Science observations and model output, has become more heterogeneous in format and more distributed across the Internet. In addition, data and metadata are becoming necessarily linked internally and externally on the Web. As a result, such content has become more difficult for providers to manage and preserve and for users to locate, understand, and consume. Specifically, it is increasingly harder to deliver relevant metadata and data processing lineage information along with the actual content consistently. Readme files, data quality information, production provenance, and other descriptive metadata are often separated in the storage level as well as in the data search and retrieval interfaces available to a user. Critical archival metadata, such as auditing trails and integrity checks, are often even more difficult for users to access, if they exist at all. We investigate the use of several open-source software frameworks to address these challenges. We use Fedora Commons Framework and its digital object abstraction as the repository, Drupal CMS as the user-interface, and the Islandora module as the connector from Drupal to Fedora Repository. With the digital object model, metadata of data description and data provenance can be associated with data content in a formal manner, so are external references and other arbitrary auxiliary information. Changes are formally audited on an object, and digital contents are versioned and have checksums automatically computed. Further, relationships among objects are formally expressed with RDF triples. Data replication, recovery, metadata export are supported with standard protocols, such as OAI-PMH. We provide a tentative comparative analysis of the chosen software stack with the Open Archival Information System (OAIS) reference model, along with our initial results with the existing terrestrial ecology data collections at NASA’s ORNL Distributed Active Archive Center for Biogeochemical Dynamics (ORNL DAAC).

PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus.

PubMed

Mellado-Gil, José Manuel; Jiménez-Moreno, Carmen María; Martin-Montalvo, Alejandro; Alvarez-Mercado, Ana Isabel; Fuente-Martin, Esther; Cobo-Vuilleumier, Nadia; Lorenzo, Petra Isabel; Bru-Tari, Eva; Herrera-Gómez, Irene de Gracia; López-Noriega, Livia; Pérez-Florido, Javier; Santoyo-López, Javier; Spyrantis, Andreas; Meda, Paolo; Boehm, Bernhard O; Quesada, Ivan; Gauthier, Benoit R

2016-04-01

A strategy to enhance pancreatic islet functional beta cell mass (BCM) while restraining inflammation, through the manipulation of molecular and cellular targets, would provide a means to counteract the deteriorating glycaemic control associated with diabetes mellitus. The aims of the current study were to investigate the therapeutic potential of such a target, the islet-enriched and diabetes-linked transcription factor paired box 4 (PAX4), to restrain experimental autoimmune diabetes (EAD) in the RIP-B7.1 mouse model background and to characterise putative cellular mechanisms associated with preserved BCM. Two groups of RIP-B7.1 mice were genetically engineered to: (1) conditionally express either PAX4 (BPTL) or its diabetes-linked mutant variant R129W (mutBPTL) using doxycycline (DOX); and (2) constitutively express luciferase in beta cells through the use of RIP. Mice were treated or not with DOX, and EAD was induced by immunisation with a murine preproinsulin II cDNA expression plasmid. The development of hyperglycaemia was monitored for up to 4 weeks following immunisation and alterations in the BCM were assessed weekly by non-invasive in vivo bioluminescence intensity (BLI). In parallel, BCM, islet cell proliferation and apoptosis were evaluated by immunocytochemistry. Alterations in PAX4- and PAX4R129W-mediated islet gene expression were investigated by microarray profiling. PAX4 preservation of endoplasmic reticulum (ER) homeostasis was assessed using thapsigargin, electron microscopy and intracellular calcium measurements. PAX4 overexpression blunted EAD, whereas the diabetes-linked mutant variant PAX4R129W did not convey protection. PAX4-expressing islets exhibited reduced insulitis and decreased beta cell apoptosis, correlating with diminished DNA damage and increased islet cell proliferation. Microarray profiling revealed that PAX4 but not PAX4R129W targeted expression of genes implicated in cell cycle and ER homeostasis. Consistent with the latter, islets overexpressing PAX4 were protected against thapsigargin-mediated ER-stress-related apoptosis. Luminal swelling associated with ER stress induced by thapsigargin was rescued in PAX4-overexpressing beta cells, correlating with preserved cytosolic calcium oscillations in response to glucose. In contrast, RNA interference mediated repression of PAX4-sensitised MIN6 cells to thapsigargin cell death. The coordinated regulation of distinct cellular pathways particularly related to ER homeostasis by PAX4 not achieved by the mutant variant PAX4R129W alleviates beta cell degeneration and protects against diabetes mellitus. The raw data for the RNA microarray described herein are accessible in the Gene Expression Omnibus database under accession number GSE62846.

Catalog of earthquake hypocenters at Alaskan volcanoes: January 1 through December 31, 2006

USGS Publications Warehouse

Dixon, James P.; Stihler, Scott D.; Power, John A.; Searcy, Cheryl

2008-01-01

Between January 1 and December 31, 2006, AVO located 8,666 earthquakes of which 7,783 occurred on or near the 33 volcanoes monitored within Alaska. Monitoring highlights in 2006 include: an eruption of Augustine Volcano, a volcanic-tectonic earthquake swarm at Mount Martin, elevated seismicity and volcanic unrest at Fourpeaked Mountain, and elevated seismicity and low-level tremor at Mount Veniaminof and Korovin Volcano. A new seismic subnetwork was installed on Fourpeaked Mountain. This catalog includes: (1) descriptions and locations of seismic instrumentation deployed in the field during 2006, (2) a description of earthquake detection, recording, analysis, and data archival systems, (3) a description of seismic velocity models used for earthquake locations, (4) a summary of earthquakes located in 2006, and (5) an accompanying UNIX tar-file with a summary of earthquake origin times, hypocenters, magnitudes, phase arrival times, location quality statistics, daily station usage statistics, and all files used to determine the earthquake locations in 2006.

Laser radar system for obstacle avoidance

NASA Astrophysics Data System (ADS)

Bers, Karlheinz; Schulz, Karl R.; Armbruster, Walter

2005-09-01

The threat of hostile surveillance and weapon systems require military aircraft to fly under extreme conditions such as low altitude, high speed, poor visibility and incomplete terrain information. The probability of collision with natural and man-made obstacles during such contour missions is high if detection capability is restricted to conventional vision aids. Forward-looking scanning laser radars which are build by the EADS company and presently being flight tested and evaluated at German proving grounds, provide a possible solution, having a large field of view, high angular and range resolution, a high pulse repetition rate, and sufficient pulse energy to register returns from objects at distances of military relevance with a high hit-and-detect probability. The development of advanced 3d-scene analysis algorithms had increased the recognition probability and reduced the false alarm rate by using more readily recognizable objects such as terrain, poles, pylons, trees, etc. to generate a parametric description of the terrain surface as well as the class, position, orientation, size and shape of all objects in the scene. The sensor system and the implemented algorithms can be used for other applications such as terrain following, autonomous obstacle avoidance, and automatic target recognition. This paper describes different 3D-imaging ladar sensors with unique system architecture but different components matched for different military application. Emphasis is laid on an obstacle warning system with a high probability of detection of thin wires, the real time processing of the measured range image data, obstacle classification und visualization.

On detecting variables using ROTSE-IIId archival data

NASA Astrophysics Data System (ADS)

Yesilyaprak, C.; Yerli, S. K.; Aksaker, N.; Gucsav, B. B.; Kiziloglu, U.; Dikicioglu, E.; Coker, D.; Aydin, E.; Ozeren, F. F.

ROTSE (Robotic Optical Transient Search Experiment) telescopes can also be used for variable star detection. As explained in the system description tep{2003PASP..115..132A}, they have a good sky coverage and they allow a fast data acquisition. The optical magnitude range varies between 7^m to 19^m. Thirty percent of the telescope time of north-eastern leg of the network, namely ROTSE-IIId (located at TUBITAK National Observatory, Bakirlitepe, Turkey http://www.tug.tubitak.gov.tr/) is owned by Turkish researchers. Since its first light (May 2004) considerably a large amount of data has been collected (around 2 TB) from the Turkish time and roughly one million objects have been identified from the reduced data. A robust pipeline has been constructed to discover new variables, transients and planetary nebulae from this archival data. In the detection process, different statistical methods were applied to the archive. We have detected thousands of variable stars by applying roughly four different tests to light curve of each star. In this work a summary of the pipeline is presented. It uses a high performance computing (HPC) algorithm which performs inhomogeneous ensemble photometry of the data on a 36 core cluster. This study is supported by TUBITAK (Scientific and Technological Research Council of Turkey) with the grant number TBAG-108T475.

Structural and Functional Concepts in Current Mouse Phenotyping and Archiving Facilities

PubMed Central

Kollmus, Heike; Post, Rainer; Brielmeier, Markus; Fernández, Julia; Fuchs, Helmut; McKerlie, Colin; Montoliu, Lluis; Otaegui, Pedro J; Rebelo, Manuel; Riedesel, Hermann; Ruberte, Jesús; Sedlacek, Radislav; de Angelis, Martin Hrabě; Schughart, Klaus

2012-01-01

Collecting and analyzing available information on the building plans, concepts, and workflow from existing animal facilities is an essential prerequisite for most centers that are planning and designing the construction of a new animal experimental research unit. Here, we have collected and analyzed such information in the context of the European project Infrafrontier, which aims to develop a common European infrastructure for high-throughput systemic phenotyping, archiving, and dissemination of mouse models. A team of experts visited 9 research facilities and 3 commercial breeders in Europe, Canada, the United States, and Singapore. During the visits, detailed data of each facility were collected and subsequently represented in standardized floor plans and descriptive tables. These data showed that because the local needs of scientists and their projects, property issues, and national and regional laws require very specific solutions, a common strategy for the construction of such facilities does not exist. However, several basic concepts were apparent that can be described by standardized floor plans showing the principle functional units and their interconnection. Here, we provide detailed information of how individual facilities addressed their specific needs by using different concepts of connecting the principle units. Our analysis likely will be valuable to research centers that are planning to design new mouse phenotyping and archiving facilities. PMID:23043807

Description of interventions is under-reported in physical therapy clinical trials.

PubMed

Hariohm, K; Jeyanthi, S; Kumar, J Saravan; Prakash, V

Amongst several barriers to the application of quality clinical evidence and clinical guidelines into routine daily practice, poor description of interventions reported in clinical trials has received less attention. Although some studies have investigated the completeness of descriptions of non-pharmacological interventions in randomized trials, studies that exclusively analyzed physical therapy interventions reported in published trials are scarce. To evaluate the quality of descriptions of interventions in both experimental and control groups in randomized controlled trials published in four core physical therapy journals. We included all randomized controlled trials published from the Physical Therapy Journal, Journal of Physiotherapy, Clinical Rehabilitation, and Archives of Physical Medicine and Rehabilitation between June 2012 and December 2013. Each randomized controlled trial (RCT) was analyzed and coded for description of interventions using the checklist developed by Schroter et al. Out of 100 RCTs selected, only 35 RCTs (35%) fully described the interventions in both the intervention and control groups. Control group interventions were poorly described in the remaining RCTs (65%). Interventions, especially in the control group, are poorly described in the clinical trials published in leading physical therapy journals. A complete description of the intervention in a published report is crucial for physical therapists to be able to use the intervention in clinical practice. Copyright © 2017 Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia. Publicado por Elsevier Editora Ltda. All rights reserved.

DNA Master File of Ground-Shock, Air-Blast, and Structure-Response Data. Volume 1. Archive Description and User’s Information

DTIC Science & Technology

1975-11-01

FLAT. MINE THROW I at NTS was a 120-ton ammonium nitrate / fuel oil (ANFO) shot, buried in alluvium, that was designed to be correlated to the...885 577L) Takahashl, S.K. Buried Fuel Capsule — Comparison of Three-Dimensional Computer Data with Experimental Data, NCEL TR-798. Port Hueneme: Naval...Perrone ATTN: Technical Library ATTN: Code 464, Jacob L. Warner Of f icer-in-Charge Civil Engineering Laboratory Naval Construction Battalion

Defense Meteorological Satellite Program - Special Sensor J5 (SSJ5) Sensor Number 16 (SN16) Calibration Report

DTIC Science & Technology

2016-07-18

Research Laboratory Space Vehicles Directorate 3550 Aberdeen Avenue SE Kirtland AFB, NM 87117-5776 8. PERFORMING ORGANIZATION REPORT NUMBER AFRL -RV...Satellite Program Space Weather Sensors (1 Dec 2000 – 30 Nov 2014), AFRL -RV-PS-TR-2016-0053, Air Force Research Laboratory, Kirtland AFB, NM, Jan 2015. [2...Archive Listing (1982-2013) and File Formats Descriptions, AFRL -RV-PR-TR-2014-0174, Air Force Research Laboratory, Kirtland AFB, NM, Aug 2014. [3

Identification and Evaluation of Submerged Anomalies, Mobile Harbor, Alabama.

DTIC Science & Technology

1984-10-01

Bay Waters , 1864-1865 APPENDIX B: Description of Maps in National ill Archives Collection V LIST OF FIGURES Figure Page cover Torpedo Raft in Mobile Bay...Anomaly D-E 51 13 Magnetometer Chart, Anomaly F 53 14 Sketch of Steel Wreckage Found at Anomaly F 54 15 Approaches to Mobile City by Water (Merrill...Osage (1863-65) 84 30 CSS Albemarle, Prototype for the Huntsville 86 31 Magnolia, CSA-Utilized Vessel 109 32 Approaches to Mobile City by Water (1864

International Data Archive

DTIC Science & Technology

1971-01-01

ARBOR, MICHIGAN A8104 © y Technical Progress Report // 4 1 January through 30 June 1971 ooO\\ Prepared in connection with research supported by...34? SSr^ ^ IRA ^ WEIS data from Janu- y . 1^66 though The data and source of each item is included in the analytic deck Also included is a descriptive...WEIGHTED, WEIGHTED, CHINESE: EXrrtA-SYSTEM ALL SIDES IN QUARREL BXTHA-nEGIONAL EXTRA-SYSTEH EXTRAS EG 10NAL (!1 EMB ER) E X T H A. J Y S T

[Karl Sudhoff].

PubMed

Kästner, Ingrid

2013-01-01

In 1914, from 6th May to 18th October, the International Exposition of book Industry and Graphic Arts (BUGRA) took place in Leipzig, then the world capital of books. Karl Sudhoff, director of the Leipzig Institute of the History of Medicine, was appointed by the executive committee of the BURGA to organize the special exhibition "Three Millennia of Graphic Arts in the Service of Science". The paper shows, following Sudhoff's own descriptions and new archival sources, the conceptual design and the contents of this exposition set up by Sudhoff.

Toward a Theory of Military Involvement in National Development in Underdeveloped Countries

DTIC Science & Technology

1984-06-01

shall assist in the collection of feces for use as fertilizers and garbage. (6). Units are required to raise livestock. 17). Units shall assist...disciplined army like the PLA which gives unquestioned obedience to: the political leadership can easily perform lowly manual tasks like collecting feces ...5,979.7 cayazs 70 avail, data 5.979.7 21ce 179C2n8 c~.vas %.o avail. eetc 17 9~. Live.;t ock 8,777 kheadS 2,472 heads 119349 , Chicken 100,940 I eads No

Low Cost Expendable TWT Amplifier for ECM.

DTIC Science & Technology

1976-08-01

Figure Tit le Page 4 1 43 Proposed Low Cost TWT 90 44 “T” Shaped Tapered Helix 91 45 Coupled Helix Input 92 46 SImulated Helix by L—C Circuit 94 47...asylTuietric mode even if the helices are syninetrical in phase and amplitude at the input. In a broadband TWT , this l eads to power holes in the f...The 1-Shaped helix was fi rst descri bed by L. Winslow , as an alternative to notching support rods in high power TWT ’ s to Increase interactive

Surfacing Rescue Container Concept Design for Trident Submarines

DTIC Science & Technology

2009-06-01

crew of their decompression obligation and will give undersea medical officers (UMO) on land the information they need to treat the crew upon arrival...ard . B ead boa ) Ba wit to ntly ora sa en s o is d OX ld er s h ule los is e v of t . L ec pu tin tte hin ad a te fety den f s to ma t...Information Service, 1970. [34] SURVIVEX 2003, Exercise Tests Disabled Submarine Survival. Horn, Wayne G. 1, s.l. : Undersea Warfare, 2003, Vol. 6, pp

Draft Environmental Statement/Environmental Impact Report. North Bay Aqueduct (Phase II Facilities) Solano County, California.

DTIC Science & Technology

1981-06-01

be Blow-off pipes in urban areas will be required to "clear" Cache Slough for the fenced to screen them from children , intake would be approximately...tip of Grand numbers of school-aged children . Island southeast of the intake locations. This disposal site, which would probably be best reached by...ind shel I h eads to Porno , Cent ral Wiat un , Wappo :in(I ’e()Ll! litrn Ma idu groups (Davis, 1974 :34-35). of the most distinctive asp~ect.,- of

Scientometric Analysis of the Journals of the Academy of Medical Sciences in Bosnia and Herzegovina

PubMed Central

Masic, Izet; Begic, Edin; Zunic, Lejla

2016-01-01

Introduction: Currently in Bosnia and Herzegovina there are 25 journals in the field of biomedicine, 6 of them are indexed in Medline/PubMed base (Medical Archives, Materia Socio-Medica, Acta Informatica Medica, Acta Medica Academica, Bosnian Journal of Basic Medical Sciences (BJBMS) and Medical Glasnik), and one (BJBMS) is indexed in Science Citation Index Expanded (SCIE)/Web of Science base. Aim: The aim of this study was to show the scope of work of the journals that were published by Academy of Medical Sciences of Bosnia and Herzegovina - Medical Archives, Materia Socio-Medica and Acta Informatica Medica. Material and Methods: The research presents a meta-analysis of three journals, or their issues, during the calendar year 2015 (retrospective and descriptive character). Results: During 2015 calendar year a total of 286 articles were published (in Medical Archives 104 (36.3%), in Materia Socio-Medica 99 (34.6%), and in Acta Informatica Medica 83 (29%)). Original articles are present in the highest number in all three journals (in Medical Archives 80.7%, in Materia Socio Medica 77.7%, and in Acta Informatica Medica 68.6%). In Medical Archives, 90.3% of the articles were related to the field of clinical medicine. In Materia Socio-Medica, the domain of clinical medicine and public health was the most represented. Preclinical areas are most frequent in Acta Informatica Medica. The period of 50-60 days for a decision on the admission of article is most common in all three journals, with trend of shortening of that period. Articles came from 19 countries, mostly from Bosnia and Herzegovina, then from Iran, Kosovo, Saudi Arabia and Greece. Conclusion: In Medical Archives original articles in the field of clinical medicine (usually internal and surgical disciplines) are most often present, and that is the case in last four years. The number of articles in Materia Socio-Medica and Acta Informatica Medica is growing from year to year. In Materia Socio-Medica there is a trend of growth of articles in the field of public health, while the most common articles in Acta Informatica Medica are about medical informatics. PMID:27041805

Scientometric Analysis of the Journals of the Academy of Medical Sciences in Bosnia and Herzegovina.

PubMed

Masic, Izet; Begic, Edin; Zunic, Lejla

2016-02-01

Currently in Bosnia and Herzegovina there are 25 journals in the field of biomedicine, 6 of them are indexed in Medline/PubMed base (Medical Archives, Materia Socio-Medica, Acta Informatica Medica, Acta Medica Academica, Bosnian Journal of Basic Medical Sciences (BJBMS) and Medical Glasnik), and one (BJBMS) is indexed in Science Citation Index Expanded (SCIE)/Web of Science base. The aim of this study was to show the scope of work of the journals that were published by Academy of Medical Sciences of Bosnia and Herzegovina - Medical Archives, Materia Socio-Medica and Acta Informatica Medica. The research presents a meta-analysis of three journals, or their issues, during the calendar year 2015 (retrospective and descriptive character). During 2015 calendar year a total of 286 articles were published (in Medical Archives 104 (36.3%), in Materia Socio-Medica 99 (34.6%), and in Acta Informatica Medica 83 (29%)). Original articles are present in the highest number in all three journals (in Medical Archives 80.7%, in Materia Socio Medica 77.7%, and in Acta Informatica Medica 68.6%). In Medical Archives, 90.3% of the articles were related to the field of clinical medicine. In Materia Socio-Medica, the domain of clinical medicine and public health was the most represented. Preclinical areas are most frequent in Acta Informatica Medica. The period of 50-60 days for a decision on the admission of article is most common in all three journals, with trend of shortening of that period. Articles came from 19 countries, mostly from Bosnia and Herzegovina, then from Iran, Kosovo, Saudi Arabia and Greece. In Medical Archives original articles in the field of clinical medicine (usually internal and surgical disciplines) are most often present, and that is the case in last four years. The number of articles in Materia Socio-Medica and Acta Informatica Medica is growing from year to year. In Materia Socio-Medica there is a trend of growth of articles in the field of public health, while the most common articles in Acta Informatica Medica are about medical informatics.

Environmental resources of selected areas of Hawaii: Cultural environment and aesthetic resources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Trettin, L.D.; Petrich, C.H.; Saulsbury, J.W.

This report has been prepared to make available and archive the background scientific data and related information collected on the cultural environment and aesthetic resources during the preparation of the environmental impact statement (EIS) for Phases 3 and 4 of the Hawaii Geothermal Project (HGP) as defined by the state of Hawaii in its April 1989 proposal to Congress. The cultural environment in the Geothermal Resource Zone (GRZ) and associated study area consists of Native Hawaiian cultural and religious practices and both Native Hawaiian and non-Native Hawaiian cultural resources. This report consists of three sections: (1) a description of Nativemore » Hawaiian cultural and religious rights, practices, and values; (2) a description of historic, prehistoric, and traditional Native Hawaiian sites; and (3) a description of other (non-native) sites that could be affected by development in the study area. Within each section, the level of descriptive detail varies according to the information currently available. The description of the cultural environment is most specific in its coverage of the Geothermal Resource Subzones in the Puna District of the island of Hawaii and the study area of South Maui. Ethnographic and archaeological reports by Cultural Advocacy Network Developing Options and International Archaeological Research Institute, Inc., respectively, supplement the descriptions of these two areas with new information collected specifically for this study. Less detailed descriptions of additional study areas on Oahu, Maui, Molokai, and the island of Hawaii are based on existing archaeological surveys.« less

Use of Archival Sources to Improve Water-Related Hazard Assessments at Volcán de Agua, Guatemala

NASA Astrophysics Data System (ADS)

Hutchison, A. A.; Cashman, K. V.; Rust, A.; Williams, C. A.

2013-12-01

This interdisciplinary study focuses on the use of archival sources from the 18th Century Spanish Empire to develop a greater understanding of mudflow trigger mechanisms at Volcán de Agua in Guatemala. Currently, hazard assessments of debris flows at Volcán de Agua are largely based on studies of analogous events, such as the mudflow at Casita Volcano in 1998 caused by excessive rainfall generated by Hurricane Mitch. A preliminary investigation of Spanish archival sources, however, indicates that a damaging mudflow from the volcano in 1717 may have been triggered by activity at the neighbouring Volcán de Fuego. A VEI 4 eruption of Fuego in late August 1717 was followed by 33 days of localized 'retumbos' and then a major local earthquake with accompanying mudflows from several 'bocas' on the southwest flank of Agua. Of particular importance for this study is an archival source from Archivos Generales de Centro América (AGCA) that consists of a series of letters, petitions and witness statements that were written and gathered following the catastrophic events of 1717. Their purpose was to argue for royal permission to relocate the capital city, which at the time was located on the lower flanks of Volcán de Agua. Within these documents there are accounts of steaming 'avenidas' of water with sulphurous smells, and quantitative descriptions that suggest fissure formation related to volcanic activity at Volcán de Fuego. Clear evidence for volcano-tectonic activity at the time, combined with the fact there is no mention of rainfall in the documents, suggest that outbursts of mud from Agua's south flank may have been caused by a volcanic perturbation of a hydrothermal system. This single example suggests that further analysis of archival documents will provide a more accurate and robust assessment of water related hazards at Volcán de Agua than currently exists.

Application of XML to Journal Table Archiving

NASA Astrophysics Data System (ADS)

Shaya, E. J.; Blackwell, J. H.; Gass, J. E.; Kargatis, V. E.; Schneider, G. L.; Weiland, J. L.; Borne, K. D.; White, R. A.; Cheung, C. Y.

1998-12-01

The Astronomical Data Center (ADC) at the NASA Goddard Space Flight Center is a major archive for machine-readable astronomical data tables. Many ADC tables are derived from published journal articles. Article tables are reformatted to be machine-readable and documentation is crafted to facilitate proper reuse by researchers. The recent switch of journals to web based electronic format has resulted in the generation of large amounts of tabular data that could be captured into machine-readable archive format at fairly low cost. The large data flow of the tables from all major North American astronomical journals (a factor of 100 greater than the present rate at the ADC) necessitates the development of rigorous standards for the exchange of data between researchers, publishers, and the archives. We have selected a suitable markup language that can fully describe the large variety of astronomical information contained in ADC tables. The eXtensible Markup Language XML is a powerful internet-ready documentation format for data. It provides a precise and clear data description language that is both machine- and human-readable. It is rapidly becoming the standard format for business and information transactions on the internet and it is an ideal common metadata exchange format. By labelling, or "marking up", all elements of the information content, documents are created that computers can easily parse. An XML archive can easily and automatically be maintained, ingested into standard databases or custom software, and even totally restructured whenever necessary. Structuring astronomical data into XML format will enable efficient and focused search capabilities via off-the-shelf software. The ADC is investigating XML's expanded hyperlinking power to enhance connectivity within the ADC data/metadata and developing XSL display scripts to enhance display of astronomical data. The ADC XML Definition Type Document can be viewed at http://messier.gsfc.nasa.gov/dtdhtml/DTD-TREE.html

EOS Data Products Handbook. Volume 2

NASA Technical Reports Server (NTRS)

Parkinson, Claire L. (Editor); Greenstone, Reynold (Editor); Closs, James (Technical Monitor)

2000-01-01

The EOS Data Products Handbook provides brief descriptions of the data products that will be produced from a range of missions of the Earth Observing System (EOS) and associated projects. Volume 1, originally published in 1997, covers the Tropical Rainfall Measuring Mission (TRMM), the Terra mission (formerly named EOS AM-1), and the Data Assimilation System, while this volume, Volume 2, covers the Active Cavity Radiometer Irradiance Monitor Satellite (ACRIMSAT), Aqua, Jason-1, Landsat 7, Meteor 3M/Stratospheric Aerosol and Gas Experiment III (SAGE III). the Quick Scatterometer (QuikScat), the Quick Total Ozone Mapping Spectrometer (Quik-TOMS), and the Vegetation Canopy Lidar (VCL) missions. Volume 2 follows closely the format of Volume 1, providing a list of products and an introduction and overview descriptions of the instruments and data processing, all introductory to the core of the book, which presents the individual data product descriptions, organized into 11 topical chapters. The product descriptions are followed by five appendices, which provide contact information for the EOS data centers that will be archiving and distributing the data sets, contact information for the science points of contact for the data products, references, acronyms and abbreviations, and a data products index.

Acquired Smell? Mature Females of the Common Green Bottle Fly Shift Semiochemical Preferences from Feces Feeding Sites to Carrion Oviposition Sites.

PubMed

Brodie, Bekka S; Babcock, Tamara; Gries, Regine; Benn, Arlan; Gries, Gerhard

2016-01-01

We investigated foraging decisions by adult females of the common green bottle fly, Lucilia sericata, in accordance with their physiological state. When we gave female flies a choice between visually occluded, fresh canine feces (feeding site) and a CO2-euthanized rat (carrion oviposition site), 3-d-old "protein-starved" females responded equally well to feces and carrion, whereas protein-fed gravid females with mature oocytes responded only to carrion, indicating resource preferences based on a fly's physiological state. Dimethyl trisulfide (DMTS) is known to attract gravid L. sericata females to carrion. Therefore, we analyzed headspace from canine feces by gas chromatographic-electroantennographic detection (GC-EAD) and GC/mass spectrometry. In bioassays, of the 17 fecal odorants that elicited GC-EAD responses from fly antennae, a blend of indole and one or more of the alcohols phenol, m-/p-cresol and 1-octen-3-ol proved as attractive to flies as canine feces. Unlike young females, gravid females need to locate carrion for oviposition and distinguish between fresh and aging carrion, the latter possibly detrimental to offspring. Gravid female L. sericata accomplish this task, in part, by responding to trace amounts of DMTS emanating from fresh carrion and by discriminating against carrion as soon it begins to produce appreciable amounts of indole, which is also the second-most abundant semiochemical in fresh canine feces, and apparently serves as an indicator of food rather than oviposition resources. Our results emphasize the importance of studying foraging choices by flies in accordance with their physiological stage.

Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD).

PubMed

Khoury, Paneez; Akuthota, Praveen; Ackerman, Steven J; Arron, Joseph R; Bochner, Bruce S; Collins, Margaret H; Kahn, Jean-Emmanuel; Fulkerson, Patricia C; Gleich, Gerald J; Gopal-Srivastava, Rashmi; Jacobsen, Elizabeth A; Leiferman, Kristen M; Francesca, Levi-Schaffer; Mathur, Sameer K; Minnicozzi, Michael; Prussin, Calman; Rothenberg, Marc E; Roufosse, Florence; Sable, Kathleen; Simon, Dagmar; Simon, Hans-Uwe; Spencer, Lisa A; Steinfeld, Jonathan; Wardlaw, Andrew J; Wechsler, Michael E; Weller, Peter F; Klion, Amy D

2018-04-19

Eosinophil-associated diseases (EADs) are rare, heterogeneous disorders characterized by the presence of eosinophils in tissues and/or peripheral blood resulting in immunopathology. The heterogeneity of tissue involvement, lack of sufficient animal models, technical challenges in working with eosinophils, and lack of standardized histopathologic approaches have hampered progress in basic research. Additionally, clinical trials and drug development for rare EADs are limited by the lack of primary and surrogate endpoints, biomarkers, and validated patient-reported outcomes. Researchers with expertise in eosinophil biology and eosinophil-related diseases reviewed the state of current eosinophil research, resources, progress, and unmet needs in the field since the 2012 meeting of the NIH Taskforce on the Research of Eosinophil-Associated Diseases (TREAD). RE-TREAD focused on gaps in basic science, translational, and clinical research on eosinophils and eosinophil-related pathogenesis. Improved recapitulation of human eosinophil biology and pathogenesis in murine models was felt to be of importance. Characterization of eosinophil phenotypes, the role of eosinophil subsets in tissues, identification of biomarkers of eosinophil activation and tissue load, and a better understanding of the role of eosinophils in human disease were prioritized. Finally, an unmet need for tools for use in clinical trials was emphasized. Histopathologic scoring, patient- and clinician-reported outcomes, and appropriate coding were deemed of paramount importance for research collaborations, drug development, and approval by regulatory agencies. Further exploration of the eosinophil genome, epigenome, and proteome was also encouraged. Although progress has been made since 2012, unmet needs in eosinophil research remain a priority. ©2018 Society for Leukocyte Biology.

Ultra Low-Cost Radar

NASA Astrophysics Data System (ADS)

Davies, P.; da Silva Curiel, A.; Eves, S.; Sweeting, M.; Thompson, A.; Hall, D.

From early 2003, Surrey Satellite Technology Limited (SSTL), together with its partners from Algeria, Nigeria and Turkey, has operated the Disaster Monitoring Constellation (DMC). During this period we have demonstrated the utility of a low-cost satellite system that uses optical sensors and is capable of providing daily imaging globally. For example, DMC data has been used operationally in the relief work in Darfur and following the Asian Tsunami. In addition to the use of the DMC to support disasters, the DMC has also been extensively used by the consortium members in support of national imaging needs and some residual system capacity has been provided to commercial customers. In the same timeframe, EADS Astrium Ltd has developed the technologies needed to implement the low-cost radar satellites of the MicroSAR range of synthetic aperture radar (SAR) satellites. EADS Astrium Ltd and SSTL are now looking to combine their expertises in low cost space technology and extend the capability of the DMC constellation by including a complementary small satellite radar sensor. The product of this activity is a satellite design that strikes an appropriate balance between revisit frequency and resolution. Hence, by comparison with other small satellite SAR concepts, the satellite described in this paper will provide broader area coverage at spatial resolutions in the region of 10 - 15m. Most significantly, perhaps, as a result of the specific cost targets imposed at the beginning of the design process, the satellite can provide this level of performance at a lower cost than other comparable space-based radar systems and significantly lower than larger, more performant, space-based radar systems.

The human Nav1.5 F1486 deletion associated with long QT syndrome leads to impaired sodium channel inactivation and reduced lidocaine sensitivity

PubMed Central

Song, Weihua; Xiao, Yucheng; Chen, Hanying; Ashpole, Nicole M; Piekarz, Andrew D; Ma, Peilin; Hudmon, Andy; Cummins, Theodore R; Shou, Weinian

2012-01-01

The deletion of phenylalanine 1486 (F1486del) in the human cardiac voltage-gated sodium channel (hNav1.5) is associated with fatal long QT (LQT) syndrome. In this study we determined how F1486del impairs the functional properties of hNav1.5 and alters action potential firing in heterologous expression systems (human embryonic kidney (HEK) 293 cells) and their native cardiomyocyte background. Cells expressing hNav1.5-F1486del exhibited a loss-of-function alteration, reflected by an 80% reduction of peak current density, and several gain-of-function alterations, including reduced channel inactivation, enlarged window current, substantial augmentation of persistent late sodium current and an increase in ramp current. We also observed substantial action potential duration (APD) prolongation and prominent early afterdepolarizations (EADs) in neonatal cardiomyocytes expressing the F1486del channels, as well as in computer simulations of myocyte activity. In addition, lidocaine sensitivity was dramatically reduced, which probably contributed to the poor therapeutic outcome observed in the patient carrying the hNav1.5-F1486del mutation. Therefore, despite the significant reduction in peak current density, the F1486del mutation also leads to substantial gain-of-function alterations that are sufficient to cause APD prolongation and EADs, the predominant characteristic of LQTs. These data demonstrate that hNav1.5 mutations can have complex functional consequences and highlight the importance of identifying the specific molecular defect when evaluating potential treatments for individuals with prolonged QT intervals. PMID:22826127

Conductive indium-tin oxidenanowire and nanotube arrays made by electrochemically assisted deposition in template membranes: switching between wire and tube growth modes by surface chemical modification of the template

NASA Astrophysics Data System (ADS)

Kovtyukhova, Nina I.; Mallouk, Thomas E.

2011-04-01

Tin-doped indium hydroxide (InSnOH) nanowires (NWs) and nanotubes (NTs) were grown from acidic aqueous solutions of inorganic precursors in a simple one-step electrochemically assisted deposition (EAD) process inside Au-plugged anodic aluminium oxide and polycarbonatemembranes. When the membranes were used without any pre-treatment, InSnOH crystals nucleated on the both the Au-cathode and pore wall surfaces. By adjusting the surface chemistry of Au or the pore walls, it was possible to switch between NW and NT growth modes. InSnOH was converted into indiumtin oxide (ITO) by annealing the InSnOH-filled membranes at 300 °C. The resulting wires and tubes were characterized by field emission scanning electron microscopy, transmission electron microscopy, X-ray and electron diffraction, Auger electron spectroscopy and electrical conductivity measurements. InSnOH and ITO NWs and NTs consisted of ~25-50 nm in size crystalline grains with the cubic crystal structures of In(OH)3 and In2O3, respectively, and showed essentially the same morphological features as planar ITO films made by the same method. Separate tin oxide/hydroxide phases were not observed by any of the characterization methods. After heating in air at 600 °C, the ITO NWs had resistivity on the order of 10°Ω cm. EAD is an inexpensive and scalable solution-based technique, and allows one to grow dense arrays of vertically aligned, crystalline and conductive ITO NWs and NTs.

Ambient particulate matter air pollution associated with acute respiratory distress syndrome in Guangzhou, China.

PubMed

Lin, Hualiang; Tao, Jun; Kan, Haidong; Qian, Zhengmin; Chen, Ailan; Du, Yaodong; Liu, Tao; Zhang, Yonghui; Qi, Yongqing; Ye, Jianjun; Li, Shuangming; Li, Wanglin; Xiao, Jianpeng; Zeng, Weilin; Li, Xing; Stamatakis, Katherine A; Chen, Xinyu; Ma, Wenjun

2018-04-30

Limited evidence exists concerning the impact of particulate pollution on acute respiratory distress syndrome (ARDS). We examined the effects of particulate pollution on emergency ambulance dispatches (EAD) for ARDS in Guangzhou, China. Daily air pollution concentrations for PM 10 , PM 2.5 , and PM 1 , as well as PM 2.5 chemical compositions, were available from a central air monitoring station. The association between incident ARDS and air pollution on the concurrent and previous 5 days was estimated by an over-dispersed Poisson generalized additive model controlling for meteorological factors, temporal trends, public holidays and day of the week. We identified a total of 17,002 EADs for ARDS during the study period. There were significant associations between concentrations of PM 10 , PM 2.5 , PM 1, and ARDS; corresponding excess risk (ER) for an interquartile range IQR increase in 1-day lagged concentration was 5.45% [95% confidence interval (CI): 1.70%, 9.33%] for PM 10 (45.4 μg/m 3 ), 4.71% (95% CI: 1.09%, 8.46%) for PM 2.5 (31.5 μg/m 3 ), and 4.45% (95% CI: 0.81%, 8.23%) for PM 1 (28.8 μg/m 3 ), respectively. For PM 2.5 chemical compositions, we found that OC, EC, sulfate and ammonium were significantly associated with ARDS. The observed effects remained even after adjusting for potentially confounding factors. This study suggests that PM 10 , PM 2.5, and PM 1 , as well as chemical constituents from combustion and secondary aerosols might be important triggers of ARDS in Guangzhou.

The changes of potassium currents in rabbit ventricle with healed myocardial infarction.

PubMed

Liu, Nian; Niu, Huiyan; Li, Yang; Zhang, Cuntai; Zhou, Qiang; Ruan, Yanfei; Pu, Jun; Lu, Zaiying

2004-01-01

To elucidate the mechanism of arrhythmia in healed myocardial infarction (HMI), the changes of action potential duration (APD), transient outward potassium current (Ito), delayed rectifier potassium current (IK) and inward rectifier potassium current (IK1) of left ventricular myocytes in non-infarcted zone of HMI were investigated. Rabbits were randomly assigned into two groups: HMI group, in which animals were subjected to thoracotomy and ligation of the circumflex coronary and sham-operated group, in which rabbits underwent thoracotomy but no conorary ligation. 3 months after the operation, the whole myocyte patch clamp technique was used to record APD, Ito, IK, and IK1 of ventricular myocytes in non-infarcted zone. Our results showed that the membrane capacitance was larger in HMI group than in sham-operated group. Action potential duration was significantly lengthened in HMI group and early afterdepolarization (EAD) appeared in HMI group. The densities of Ito, I(K, tail), and IK1 were reduced significantly in HMI group, from 6.72 +/- 0.42 pA/pF, 1.54 +/- 0.13 pA/pF and 25.6 +/- 2.6 pA/pF in sham-operated group to 4.03 +/- 0.33 pA/pF, 1.14 +/- 0.11 pA/pF and 17.6 +/- 2.3 pA/pF, respectively. It is concluded that the reduced densities of Ito, I(K, tail) and IK1 in ventricular myocytes of non-infarcted zone in HMI were responsible for the prolongation of APD and the presentation of EAD which played important roles in the development of malignant arrhythmia in HMI.

Campaign to counter a deteriorating consumer market: Philip Morris's Project Sunrise.

PubMed

Givel, M

2013-02-01

From 1997 to 2000, Philip Morris implemented Project Sunrise. This paper discusses the impact of this project on national and Philip Morris's cigarette unit sales, public opinion about smoking and secondhand tobacco smoke, and national prevalence trends for tobacco use. A qualitative archival content analysis of Project Sunrise from 1997 to 2000, and a descriptive statistical analysis of cigarette unit sales and operating profits, acceptability of smoking and secondhand tobacco smoke, and national prevalence trends for tobacco use from 1996 to 2006. Qualitative data sources related to Project Sunrise found on WebCat, Pubmed.com, LexisNexis Academic and Philip Morris's website, and archived tobacco industry documents were analysed using NVivo Version 9.0. A descriptive statistical analysis of cigarette unit sales, public opinion about smoking and secondhand tobacco smoke, and national prevalence trends for tobacco use was undertaken. Project Sunrise was a high-level strategic corporate plan to maintain profits that included four possible scenarios resulting in seven interwoven strategies. However, national prevalence rates for tobacco use declined, sales of national and Philip Morris cigarettes declined, operating profits remained at substantially lower levels after 2000 from 2001 to 2006, and a large majority of Americans agreed that there were significant health dangers associated with smoking and secondhand tobacco smoke. The impact of Project Sunrise, including countering the anti-tobacco movement, was less than successful in the USA. Copyright © 2012 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

Intoxicated witnesses and suspects: an archival analysis of their involvement in criminal case processing.

PubMed

Palmer, Francesca T; Flowe, Heather D; Takarangi, Melanie K T; Humphries, Joyce E

2013-02-01

Research about intoxicated witnesses and criminal suspects is surprisingly limited, considering the police believe that they are quite ubiquitous. In the present study, we assessed the involvement of intoxicated witnesses and suspects in the investigation of rape, robbery, and assault crimes by analyzing cases that were referred by the police to a prosecutor's office. Results indicated that intoxicated witnesses and suspects played an appreciable role in criminal investigations: Intoxicated witnesses were just as likely as sober ones to provide a description of the culprit and to take an identification test, suggesting criminal investigators treat intoxicated and sober witnesses similarly. Moreover, intoxicated suspects typically admitted to the police that they had consumed alcohol and/or drugs, and they were usually arrested on the same day as the crime. This archival analysis highlights the many ways in which alcohol impacts testimony during criminal investigations and underscores the need for additional research to investigate best practices for obtaining testimony from intoxicated witnesses and suspects.

[Manuscript "Many different remedies for headache treatment" from the archives of Sinj Friary].

PubMed

Kujundzic, Nikola; Glibota, Milan; Inic, Suzana

2011-01-01

Manuscripts containing collections of folk recipes for treatment of deseases were written mostly by Catholic priests especially Franciscians in Croatia in the past centuries. They were used as manuals for preparation of remedies and gave directions for their use. These writtings provide valuble data for etnographers and historians of ethnomedicine. The paper describes the manuscript "Many different remedies for headache treatment" written by unknown author probably in 18. century in Sinj, Dalmatia. The manuscript was found in the archives of Sinj Friary. The collection contains 16 recipes for headache treatment. Materia medica of the manuscript is composed of drugs of plant origin. Valuable information is given about the folk names for medicinal plants as well as descriptions of the ways of preparing remedies. Latin as well as contemporaly croatian names are attributed to the plants species mentioned in the manuscript. Use of the plants for treatment of the specific deseases were compared with their use in modern fitotherapy.

The metagenomic data life-cycle: standards and best practices

PubMed Central

ten Hoopen, Petra; Finn, Robert D.; Bongo, Lars Ailo; Corre, Erwan; Meyer, Folker; Mitchell, Alex; Pelletier, Eric; Pesole, Graziano; Santamaria, Monica; Willassen, Nils Peder

2017-01-01

Abstract Metagenomics data analyses from independent studies can only be compared if the analysis workflows are described in a harmonized way. In this overview, we have mapped the landscape of data standards available for the description of essential steps in metagenomics: (i) material sampling, (ii) material sequencing, (iii) data analysis, and (iv) data archiving and publishing. Taking examples from marine research, we summarize essential variables used to describe material sampling processes and sequencing procedures in a metagenomics experiment. These aspects of metagenomics dataset generation have been to some extent addressed by the scientific community, but greater awareness and adoption is still needed. We emphasize the lack of standards relating to reporting how metagenomics datasets are analysed and how the metagenomics data analysis outputs should be archived and published. We propose best practice as a foundation for a community standard to enable reproducibility and better sharing of metagenomics datasets, leading ultimately to greater metagenomics data reuse and repurposing. PMID:28637310

VO-Dance an IVOA tools to easy publish data into VO and it's extension on planetology request

NASA Astrophysics Data System (ADS)

Smareglia, R.; Capria, M. T.; Molinaro, M.

2012-09-01

Data publishing through the self standing portals can be joined to VO resource publishing, i.e. astronomical resources deployed through VO compliant services. Since the IVOA (International Virtual Observatory Alliance) provides many protocols and standards for the various data flavors (images, spectra, catalogues … ), and since the data center has as a goal to grow up in number of hosted archives and services providing, the idea arose to find a way to easily deploy and maintain VO resources. VO-Dance is a java web application developed at IA2 that addresses this idea creating, in a dynamical way, VO resources out of database tables or views. It is structured to be potentially DBMS and platform independent and consists of 3 main tokens, an internal DB to store resources description and model metadata information, a restful web application to deploy the resources to the VO community. It's extension to planetology request is under study to best effort INAF software development and archive efficiency.

Consideration of the effect for enhancing the disaster prevention awareness by visualization of the tsunami lore

NASA Astrophysics Data System (ADS)

Chiharu, M.

2017-12-01

One effective measure for enhancing the residents' disaster prevention awareness is to know the natural hazard which has occurred in the past at residence. Mie Disaster Mitigation Center had released the digital archive for promoting an understanding of disaster prevention on April 28, 2015. This archive is recording the past disaster information as digital catalog. An effective contribution to enhancement of the inhabitants' disaster prevention awareness is expected. It includes the following contents (1) The interview with disaster victim (the 1944 Tonankai Earthquake, The Ise Bay Typhoon and so on) (2) The information on "monument of Tsunami" (3) The description of disaster on the local history material (the school history books, municipal history books, and so on). These contents are being dropped on a map and it is being shown clearly geographically. For all age groups, this way makes it easy to understand that the past disaster information relates to their residence address.

J. M. Despréaux' lichens from the Canary Islands and West Africa: an account of a 19th century collection found in an English archive.

PubMed

Aguirre-Hudson, Begoña; Whitworth, Isabella; Spooner, Brian M

2011-01-01

This is an historical and descriptive account of 28 herbarium specimens, 27 lichens and an alga, found in the archives of Charles Chalcraft, a descendant of the Bedford family, who were dye manufacturers in Leeds, England, in the 19th century. The lichens comprise 13 different morphotypes collected in the Canary Islands and West Africa by the French botanist J. M. Despréaux between 1833 and 1839. The collections include samples of "Roccella fuciformis", "R. phycopsis" and "R. tinctoria" (including the fertile morphotype "R. canariensis"), "Ramalina crispatula" and "R. cupularis", two distinct morphotypes of "Sticta", "S. canariensis" and "S. dufouri", "Physconia enteroxantha", "Pseudevernia furfuracea var. ceratea" and "Pseudocyphellaria argyracea". The herbarium also includes authentic material of "Parmotrema tinctorum" and a probable syntype of "Seirophora scorigena". Most of these species are known as a source of the purple dye orchil, which was used to dye silk and wool.

Data Integration Using SOAP in the VSO

NASA Astrophysics Data System (ADS)

Tian, K. Q.; Bogart, R. S.; Davey, A.; Dimitoglou, G.; Gurman, J. B.; Hill, F.; Martens, P. C.; Wampler, S.

2003-05-01

The Virtual Solar Observatory (VSO) project has implemented a time interval search for all four participating data archives. The back-end query services are implemented as web services, and are accessible via SOAP. SOAP (Simple Object Access Protocol) defines an RPC (Remote Procedure Call) mechanism that employs HTTP as its transport and encodes the client-server interactions (request and response messages) in XML (eXtensible Markup Language) documents. In addition to its core function of identifying relevant datasets in the local archive, the SOAP server at each data provider acts as a "wrapper" that maps descriptions in an abstract data model to those in the provider-specific data model, and vice versa. It is in this way that VSO integrates heterogeneous data services and allows access to them using a common interface. Our experience with SOAP has been fruitful. It has proven to be a better alternative to traditional web access methods, namely POST and GET, because of its flexibility and interoperability.

Agile based "Semi-"Automated Data ingest process : ORNL DAAC example

NASA Astrophysics Data System (ADS)

Santhana Vannan, S. K.; Beaty, T.; Cook, R. B.; Devarakonda, R.; Hook, L.; Wei, Y.; Wright, D.

2015-12-01

The ORNL DAAC archives and publishes data and information relevant to biogeochemical, ecological, and environmental processes. The data archived at the ORNL DAAC must be well formatted, self-descriptive, and documented, as well as referenced in a peer-reviewed publication. The ORNL DAAC ingest team curates diverse data sets from multiple data providers simultaneously. To streamline the ingest process, the data set submission process at the ORNL DAAC has been recently updated to use an agile process and a semi-automated workflow system has been developed to provide a consistent data provider experience and to create a uniform data product. The goals of semi-automated agile ingest process are to: 1.Provide the ability to track a data set from acceptance to publication 2. Automate steps that can be automated to improve efficiencies and reduce redundancy 3.Update legacy ingest infrastructure 4.Provide a centralized system to manage the various aspects of ingest. This talk will cover the agile methodology, workflow, and tools developed through this system.

The metagenomic data life-cycle: standards and best practices

DOE Office of Scientific and Technical Information (OSTI.GOV)

ten Hoopen, Petra; Finn, Robert D.; Bongo, Lars Ailo

Metagenomics data analyses from independent studies can only be compared if the analysis workflows are described in a harmonised way. In this overview, we have mapped the landscape of data standards available for the description of essential steps in metagenomics: (1) material sampling, (2) material sequencing (3) data analysis and (4) data archiving & publishing. Taking examples from marine research, we summarise essential variables used to describe material sampling processes and sequencing procedures in a metagenomics experiment. These aspects of metagenomics dataset generation have been to some extent addressed by the scientific community but greater awareness and adoption is stillmore » needed. We emphasise the lack of standards relating to reporting how metagenomics datasets are analysed and how the metagenomics data analysis outputs should be archived and published. We propose best practice as a foundation for a community standard to enable reproducibility and better sharing of metagenomics datasets, leading ultimately to greater metagenomics data reuse and repurposing.« less

Description of data on the Nimbus 7 LIMS map archive tape: Temperature and geopotential height

NASA Technical Reports Server (NTRS)

Haggard, K. V.; Remsberg, E. E.; Grose, W. L.; Russell, J. M., III; Marshall, B. T.; Lingenfelser, G.

1986-01-01

The process by which the analysis of the Limb Infared Monitor of the Stratosphere (LIMS) experiment data were used to produce estimates of synoptic maps of temperature and geopotential height is described. In addition to a detailed description of the analysis procedure, several interesting features in the data are discussed and these features are used to demonstrate how the analysis procedure produced the final maps and how one can estimate the uncertainties in the maps. In addition, features in the analysis are noted that would influence how one might use, or interpret, the results. These include subjects such as smoothing and the interpretation of wave components. While some suggestions are made for an improved analysis of the data, it is shown that, in general, the maps are an excellent estimation of the synoptic fields.

The design of a petabyte archive and distribution system for the NASA ECS project

NASA Technical Reports Server (NTRS)

Caulk, Parris M.

1994-01-01

The NASA EOS Data and Information System (EOSDIS) Core System (ECS) will contain one of the largest data management systems ever built - the ECS Science and Data Processing System (SDPS). SDPS is designed to support long term Global Change Research by acquiring, producing, and storing earth science data, and by providing efficient means for accessing and manipulating that data. The first two releases of SDPS, Release A and Release B, will be operational in 1997 and 1998, respectively. Release B will be deployed at eight Distributed Active Archiving Centers (DAAC's). Individual DAAC's will archive different collections of earth science data, and will vary in archive capacity. The storage and management of these data collections is the responsibility of the SDPS Data Server subsystem. It is anticipated that by the year 2001, the Data Server subsystem at the Goddard DAAC must support a near-line data storage capacity of one petabyte. The development of SDPS is a system integration effort in which COTS products will be used in favor of custom components in very possible way. Some software and hardware capabilities required to meet ECS data volume and storage management requirements beyond 1999 are not yet supported by available COTS products. The ECS project will not undertake major custom development efforts to provide these capabilities. Instead, SDPS and its Data Server subsystem are designed to support initial implementations with current products, and provide an evolutionary framework that facilitates the introduction of advanced COTS products as they become available. This paper provides a high-level description of the Data Server subsystem design from a COTS integration standpoint, and discussed some of the major issues driving the design. The paper focuses on features of the design that will make the system scalable and adaptable to changing technologies.

Testing the Archivas Cluster (Arc) for Ozone Monitoring Instrument (OMI) Scientific Data Storage

NASA Technical Reports Server (NTRS)

Tilmes, Curt

2005-01-01

The Ozone Monitoring Instrument (OMI) launched on NASA's Aura Spacecraft, the third of the major platforms of the EOS program on July 15,2004. In addition to the long term archive and distribution of the data from OM1 through the Goddard Earth Science Distributed Active Archive Center (GESDAAC), we are evaluating other archive mechanisms that can archive the data in a more immediately available method where it can be used for futher data production and analysis. In 2004, Archivas, Inc. was selected by NASA s Small Business Innovative Research (SBIR) program for the development of their Archivas Cluster (ArC) product. Arc is an online disk based system utilizing self-management and automation on a Linux cluster. Its goal is to produce a low cost solution coupled with the ease of management. The OM1 project is an application partner of the SBIR program, and has deployed a small cluster (5TB) based on the beta Archwas software. We performed extensive testing of the unit using production OM1 data since launch. In 2005, Archivas, Inc. was funded in SBIR Phase II for further development, which will include testing scalability with the deployment of a larger (35TB) cluster at Goddard. We plan to include Arc in the OM1 Team Leader Computing Facility (TLCF) hosting OM1 data for direct access and analysis by the OMI Science Team. This presentation will include a brief technical description of the Archivas Cluster, a summary of the SBIR Phase I beta testing results, and an overview of the OMI ground data processing architecture including its interaction with the Phase II Archivas Cluster and hosting of OMI data for the scientists.

Improving Access to NASA Earth Science Data through Collaborative Metadata Curation

NASA Astrophysics Data System (ADS)

Sisco, A. W.; Bugbee, K.; Shum, D.; Baynes, K.; Dixon, V.; Ramachandran, R.

2017-12-01

The NASA-developed Common Metadata Repository (CMR) is a high-performance metadata system that currently catalogs over 375 million Earth science metadata records. It serves as the authoritative metadata management system of NASA's Earth Observing System Data and Information System (EOSDIS), enabling NASA Earth science data to be discovered and accessed by a worldwide user community. The size of the EOSDIS data archive is steadily increasing, and the ability to manage and query this archive depends on the input of high quality metadata to the CMR. Metadata that does not provide adequate descriptive information diminishes the CMR's ability to effectively find and serve data to users. To address this issue, an innovative and collaborative review process is underway to systematically improve the completeness, consistency, and accuracy of metadata for approximately 7,000 data sets archived by NASA's twelve EOSDIS data centers, or Distributed Active Archive Centers (DAACs). The process involves automated and manual metadata assessment of both collection and granule records by a team of Earth science data specialists at NASA Marshall Space Flight Center. The team communicates results to DAAC personnel, who then make revisions and reingest improved metadata into the CMR. Implementation of this process relies on a network of interdisciplinary collaborators leveraging a variety of communication platforms and long-range planning strategies. Curating metadata at this scale and resolving metadata issues through community consensus improves the CMR's ability to serve current and future users and also introduces best practices for stewarding the next generation of Earth Observing System data. This presentation will detail the metadata curation process, its outcomes thus far, and also share the status of ongoing curation activities.

NASA's Long-Term Archive (LTA) of ICESat Data at the National Snow and Ice Data Center (NSIDC)

NASA Astrophysics Data System (ADS)

Fowler, D. K.; Moses, J. F.; Dimarzio, J. P.; Webster, D.

2011-12-01

Data Stewardship, preservation, and reproducibility are becoming principal parts of a data manager's work. In an era of distributed data and information systems, where the host location ought to be transparent to the internet user, it is of vital importance that organizations make a commitment to both current and long-term goals of data management and the preservation of scientific data. NASA's EOS Data and Information System (EOSDIS) is a distributed system of discipline-specific archives and mission-specific science data processing facilities. Satellite missions and instruments go through a lifecycle that involves pre-launch calibration, on-orbit data acquisition and product generation, and final reprocessing. Data products and descriptions flow to the archives for distribution on a regular basis during the active part of the mission. However there is additional information from the product generation and science teams needed to ensure the observations will be useful for long term climate studies. Examples include ancillary input datasets, product generation software, and production history as developed by the team during the course of product generation. These data and information will need to be archived after product data processing is completed. Using inputs from the USGCRP Workshop on Long Term Archive Requirements (1998), discussions with EOS instrument teams, and input from the 2011 ESIPS Federation meeting, NASA is developing a set of Earth science data and information content requirements for long term preservation that will ultimately be used for all the EOS missions as they come to completion. Since the ICESat/GLAS mission is one of the first to come to an end, NASA and NSIDC are preparing for long-term support of the ICESat mission data now. For a long-term archive, it is imperative that there is sufficient information about how products were prepared in order to convince future researchers that the scientific results are accurate, understandable, useable, and reproducible. Our experience suggests data centers know what to preserve in most cases, i.e., the processing algorithms along with the Level 0 or Level 1a input and ancillary products used to create the higher-level products will be archived and made available to users. In other cases the data centers must seek guidance from the science team, e.g., for pre-launch, calibration/validation, and test data. All these data are an important part of product provenance, contributing to and helping establish the integrity of the scientific observations for long term climate studies. In this presentation we will describe application of information content requirements, guidance from the ICESat/GLAS Science Team and the flow of additional information from the ICESat Science team and Science Investigator-Led Processing System to the Distributed Active Archive Center.

THE CDF ARCHIVE: HERSCHEL PACS AND SPIRE SPECTROSCOPIC DATA PIPELINE AND PRODUCTS FOR PROTOSTARS AND YOUNG STELLAR OBJECTS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Green, Joel D.; Yang, Yao-Lun; II, Neal J. Evans

2016-03-15

We present the COPS-DIGIT-FOOSH (CDF) Herschel spectroscopy data product archive, and related ancillary data products, along with data fidelity assessments, and a user-created archive in collaboration with the Herschel-PACS and SPIRE ICC groups. Our products include datacubes, contour maps, automated line fitting results, and best 1D spectra products for all protostellar and disk sources observed with PACS in RangeScan mode for two observing programs: the DIGIT Open Time Key Program (KPOT-nevans-1 and SDP-nevans-1; PI: N. Evans), and the FOOSH Open Time Program (OT1-jgreen02-2; PI: J. Green). In addition, we provide our best SPIRE-FTS spectroscopic products for the COPS Open Time Program (OT2-jgreen02-6;more » PI: J. Green) and FOOSH sources. We include details of data processing, descriptions of output products, and tests of their reliability for user applications. We identify the parts of the data set to be used with caution. The resulting absolute flux calibration has improved in almost all cases. Compared to previous reductions, the resulting rotational temperatures and numbers of CO molecules have changed substantially in some sources. On average, however, the rotational temperatures have not changed substantially (<2%), but the number of warm (T{sub rot} ∼ 300 K) CO molecules has increased by about 18%.« less

The CDF Archive: Herschel PACS and SPIRE Spectroscopic Data Pipeline and Products for Protostars and Young Stellar Objects

NASA Astrophysics Data System (ADS)

Green, Joel D.; Yang, Yao-Lun; Evans, Neal J., II; Karska, Agata; Herczeg, Gregory; van Dishoeck, Ewine F.; Lee, Jeong-Eun; Larson, Rebecca L.; Bouwman, Jeroen

2016-03-01

We present the COPS-DIGIT-FOOSH (CDF) Herschel spectroscopy data product archive, and related ancillary data products, along with data fidelity assessments, and a user-created archive in collaboration with the Herschel-PACS and SPIRE ICC groups. Our products include datacubes, contour maps, automated line fitting results, and best 1D spectra products for all protostellar and disk sources observed with PACS in RangeScan mode for two observing programs: the DIGIT Open Time Key Program (KPOT_nevans1 and SDP_nevans_1; PI: N. Evans), and the FOOSH Open Time Program (OT1_jgreen02_2; PI: J. Green). In addition, we provide our best SPIRE-FTS spectroscopic products for the COPS Open Time Program (OT2_jgreen02_6; PI: J. Green) and FOOSH sources. We include details of data processing, descriptions of output products, and tests of their reliability for user applications. We identify the parts of the data set to be used with caution. The resulting absolute flux calibration has improved in almost all cases. Compared to previous reductions, the resulting rotational temperatures and numbers of CO molecules have changed substantially in some sources. On average, however, the rotational temperatures have not changed substantially (<2%), but the number of warm (Trot ∼ 300 K) CO molecules has increased by about 18%.

Supporting the Use of GPM-GV Field Campaign Data Beyond Project Scientists

NASA Astrophysics Data System (ADS)

Weigel, A. M.; Smith, D. K.; Sinclair, L.; Bugbee, K.

2017-12-01

The Global Precipitation Measurement (GPM) Mission Ground Validation (GV) consisted of a collection of field campaigns at various locations focusing on particular aspects of precipitation. Data collected during the GPM-GV are necessary for better understanding the instruments and algorithms used to monitor water resources, study the global hydrologic cycle, understand climate variability, and improve weather prediction. The GPM-GV field campaign data have been archived at the NASA Global Hydrology Resource Center (GHRC) Distributed Achive Archive Center (DAAC). These data consist of a heterogeneous collection of observations that require careful handling, full descriptive user guides, and helpful instructions for data use. These actions are part of the data archival process. In addition, the GHRC focuses on expanding the use of GPM-GV data beyond the validation and instrument researchers that participated in the field campaigns. To accomplish this, GHRC ties together the similarities and differences between the various field campaigns with the goal of improving user documents to be more easily read by those outside the field of research. In this poster, the authors will describe the GPM-GV datasets, discuss data use among the broader community, outline the types of problems/issues with these datasets, demonstrate what tools support data visualization and use, and highlight the outreach materials developed to educate both younger and general audiences about the data.

Ultra-High-Modulus Graphite-Epoxy Conical Shell Development. Supplement

DTIC Science & Technology

1979-04-01

934 (0/±45/90)8 t = o.040 T - 300/934 MS124815 CRES HELICOIL O. 190-32 TiffiEAD, 3 DIA · NOM. LG. Install per MS33537 Oirnensions are inches...1613 psi avg 325F critu 1384 psi avg 3 -29 0.5 i ’ I 2.0 DIA • .. - -..-.! 0.75 DIA . + LOAD t LOAD THREAD Dimensions are inches. STEEL...THiCK T-300/934 (Ol!. 45/90Jsc T-300/934 [ 0/:!::. 45/90]5 t := 0.040 MS124815 CRES HEUCOIL I I I I ’ ’ I I ~ ;, 0 . 190-32 WREAD, 3 DIA

BKCASE (trademark): Body of Knowledge and Curriculum to Advance Systems Engineering

DTIC Science & Technology

2010-10-01

Association Francaise d‘lingeniere Systeme, France Tim  Ferris University of South Australia, Australia Kevin Forsberg Center for Systems Management US 7... Lee Defence Science and Technology Agency,  Singapore Ray Madachy Naval Postgraduate School, US James Martin Aerospace Corporation US    ,  Greg...Pyster Stevens Institute of Technology, US Garry Roedler Lockheed Martin, US Jean‐Claude Roussel EADS, France 9/2010 Sven‐Olaf Schulze Berner & Mattner

Why and how Mastering an Incremental and Iterative Software Development Process

NASA Astrophysics Data System (ADS)

Dubuc, François; Guichoux, Bernard; Cormery, Patrick; Mescam, Jean Christophe

2004-06-01

One of the key issues regularly mentioned in the current software crisis of the space domain is related to the software development process that must be performed while the system definition is not yet frozen. This is especially true for complex systems like launchers or space vehicles.Several more or less mature solutions are under study by EADS SPACE Transportation and are going to be presented in this paper. The basic principle is to develop the software through an iterative and incremental process instead of the classical waterfall approach, with the following advantages:- It permits systematic management and incorporation of requirements changes over the development cycle with a minimal cost. As far as possible the most dimensioning requirements are analyzed and developed in priority for validating very early the architecture concept without the details.- A software prototype is very quickly available. It improves the communication between system and software teams, as it enables to check very early and efficiently the common understanding of the system requirements.- It allows the software team to complete a whole development cycle very early, and thus to become quickly familiar with the software development environment (methodology, technology, tools...). This is particularly important when the team is new, or when the environment has changed since the previous development. Anyhow, it improves a lot the learning curve of the software team.These advantages seem very attractive, but mastering efficiently an iterative development process is not so easy and induces a lot of difficulties such as:- How to freeze one configuration of the system definition as a development baseline, while most of thesystem requirements are completely and naturally unstable?- How to distinguish stable/unstable and dimensioning/standard requirements?- How to plan the development of each increment?- How to link classical waterfall development milestones with an iterative approach: when should theclassical reviews be performed: Software Specification Review? Preliminary Design Review? CriticalDesign Review? Code Review? Etc...Several solutions envisaged or already deployed by EADS SPACE Transportation will be presented, both from a methodological and technological point of view:- How the MELANIE EADS ST internal methodology improves the concurrent engineering activitiesbetween GNC, software and simulation teams in a very iterative and reactive way.- How the CMM approach can help by better formalizing Requirements Management and Planningprocesses.- How the Automatic Code Generation with "certified" tools (SCADE) can still dramatically shorten thedevelopment cycle.Then the presentation will conclude by showing an evaluation of the cost and planning reduction based on a pilot application by comparing figures on two similar projects: one with the classical waterfall process, the other one with an iterative and incremental approach.

["... and of course my views have become more independent"--Friedrich Ratzel's letters to Ernst Haeckel, his mentor and academic colleague].

PubMed

Zigman, Peter M

2009-01-01

This article for the first time provides an edition and commentary of the letters of Friedrich Ratzel to his older colleague, teacher and mentor, Ernst Haeckel, which are kept in the archive of the Ernst-Haeckel-House (memorial museum) in Jena. Altogether fifteen letters and one postcard are presented. Haeckel's letters to Ratzel are considered to be lost. The edition is prefaced with a detailed description of Ratzel's life, career and work, as a part of the edition.

WCRP surface radiation budget shortwave data product description, version 1.1

NASA Technical Reports Server (NTRS)

Whitlock, C. H.; Charlock, T. P.; Staylor, W. F.; Pinker, R. T.; Laszlo, I.; Dipasquale, R. C.; Ritchey, N. A.

1993-01-01

Shortwave radiative fluxes which reach the Earth's surface are key elements that influence both atmospheric and oceanic circulation. The World Climate Research Program has established the Surface Radiation Budget climatology project with the ultimate goal of determining the various components of the surface radiation budget from satellite data on a global scale. This report describes the first global product that is being produced and archived as part of that effort. The interested user can obtain the monthly global data sets free of charge using e-mail procedures.

GLAS Long-Term Archive: Preservation and Stewardship for a Vital Earth Observing Mission

NASA Astrophysics Data System (ADS)

Fowler, D. K.; Moses, J. F.; Zwally, J.; Schutz, B. E.; Hancock, D.; McAllister, M.; Webster, D.; Bond, C.

2012-12-01

Data Stewardship, preservation, and reproducibility are fast becoming principal parts of a data manager's work. In an era of distributed data and information systems, it is of vital importance that organizations make a commitment to both current and long-term goals of data management and the preservation of scientific data. Satellite missions and instruments go through a lifecycle that involves pre-launch calibration, on-orbit data acquisition and product generation, and final reprocessing. Data products and descriptions flow to the archives for distribution on a regular basis during the active part of the mission. However there is additional information from the product generation and science teams needed to ensure the observations will be useful for long term climate studies. Examples include ancillary input datasets, product generation software, and production history as developed by the team during the course of product generation. These data and information will need to be archived after product data processing is completed. NASA has developed a set of Earth science data and information content requirements for long term preservation that is being used for all the EOS missions as they come to completion. Since the ICESat/GLAS mission was one of the first to end, NASA and NSIDC, in collaboration with the science team, are collecting data, software, and documentation, preparing for long-term support of the ICESat mission. For a long-term archive, it is imperative to preserve sufficient information about how products were prepared in order to ensure future researchers that the scientific results are accurate, understandable, and useable. Our experience suggests data centers know what to preserve in most cases. That is, the processing algorithms along with the Level 0 or Level 1a input and ancillary products used to create the higher-level products will be archived and made available to users. In other cases, such as pre-launch, calibration/validation, and test data, the data centers must seek guidance from the science team. All these data are essential for product provenance, contributing to and helping establish the integrity of the scientific observations for long term climate studies. In this presentation we will describe application of information gathering with guidance from the ICESat/GLAS Science Team, and the flow of additional information from the ICESat Science team and Science Investigator-Led Processing System to the NSIDC Distributed Active Archive Center. This presentation will also cover how we envision user support through the years of the Long-Term Archive.

Anxiety, stress and depression in family caregivers of the mentally ill.

PubMed

Cabral, Lídia; Duarte, João; Ferreira, Manuela; dos Santos, Carlos

2014-11-01

The current policy guidelines on mental health aim to keep the mentally ill within the community, with the development of social support, including families, hence the emergence of the role of the family caregiver. To identify socio-demographic variables influencing anxiety, depression and stress for the informal caregivers of the mentally ill; to determine the influence of family background variables on caregiver anxiety, depression and stress; to analyse the relationship between social support and caregiver overload with caregiver anxiety, depression and stress. Cross-sectional, descriptive and correlational study with 104 caregivers, mostly female (62.5%), aged between 22 and 77 years with a mean age of 52.03 years. The following were used as instruments: the Family Apgar Scale; the Satisfaction with Social Support Scale (ESSS); the Caregiver Overload Scale (ESC); the Anxiety, Depression and Stress Scales (EADS-21). We found that females have higher rates (P<.05) of anxiety, depression and stress; participants with less education have more anxiety than those with higher and secondary education (P=.001); caregivers living in rural areas have higher levels of depression (P=.044) and stress (P=.041); those who perceive belonging to families with marked dysfunctions have higher levels of depression (P=.0.001) and stress (P=.000); the higher the overload, the higher the levels of anxiety (P=.002), depression and stress (P=.000). I tis necessary to develop strategies for local and community intervention to promote mental health and prevent mental illness. Copyright © 2014 Elsevier España, S.L.U. All rights reserved.

Use of data description languages in the interchange of data

NASA Technical Reports Server (NTRS)

Pignede, M.; Real-Planells, B.; Smith, S. R.

1994-01-01

The Consultative Committee for Space Data Systems (CCSDS) is developing Standards for the interchange of information between systems, including those operating under different environments. The objective is to perform the interchange automatically, i.e. in a computer interpretable manner. One aspect of the concept developed by CCSDS is the use of a separate data description to specify the data being transferred. Using the description, data can then be automatically parsed by the receiving computer. With a suitably expressive Data Description Language (DDL), data formats of arbitrary complexity can be handled. The advantages of this approach are: (1) that the description need only be written and distributed once to all users, and (2) new software does not need to be written for each new format, provided generic tools are available to support writing and interpretation of descriptions and the associated data instances. Consequently, the effort of 'hard coding' each new format is avoided and problems of integrating multiple implementations of a given format by different users are avoided. The approach is applicable in any context where computer parsable description of data could enhance efficiency (e.g. within a spacecraft control system, a data delivery system or an archive). The CCSDS have identified several candidate DDL's: EAST (Extended Ada Subset), TSDN (Transfer Syntax Data Notation) and MADEL (Modified ASN.1 as a Data Description Language -- a DDL based on the Abstract Syntax Notation One - ASN.1 - specified in the ISO/IEC 8824). This paper concentrates on ESA's development of MADEL. ESA have also developed a 'proof of concept' prototype of the required support tools, implemented on a PC under MS-DOS, which has successfully demonstrated the feasibility of the approach, including the capability within an application of retrieving and displaying particular data elements, given its MADEL description (i.e. a data description written in MADEL). This paper outlines the work done to date and assesses the applicability of this modified ASN.1 as a DDL. The feasibility of the approach is illustrated with several examples.

Description of Selected Algorithms and Implementation Details of a Concept-Demonstration Aircraft VOrtex Spacing System (AVOSS)

NASA Technical Reports Server (NTRS)

Hinton, David A.

2001-01-01

A ground-based system has been developed to demonstrate the feasibility of automating the process of collecting relevant weather data, predicting wake vortex behavior from a data base of aircraft, prescribing safe wake vortex spacing criteria, estimating system benefit, and comparing predicted and observed wake vortex behavior. This report describes many of the system algorithms, features, limitations, and lessons learned, as well as suggested system improvements. The system has demonstrated concept feasibility and the potential for airport benefit. Significant opportunities exist however for improved system robustness and optimization. A condensed version of the development lab book is provided along with samples of key input and output file types. This report is intended to document the technical development process and system architecture, and to augment archived internal documents that provide detailed descriptions of software and file formats.

A Data Quality Filter for PMU Measurements: Description, Experience, and Examples

DOE Office of Scientific and Technical Information (OSTI.GOV)

Follum, James D.; Amidan, Brett G.

Networks of phasor measurement units (PMUs) continue to grow, and along with them, the amount of data available for analysis. With so much data, it is impractical to identify and remove poor quality data manually. The data quality filter described in this paper was developed for use with the Data Integrity and Situation Awareness Tool (DISAT), which analyzes PMU data to identify anomalous system behavior. The filter operates based only on the information included in the data files, without supervisory control and data acquisition (SCADA) data, state estimator values, or system topology information. Measurements are compared to preselected thresholds tomore » determine if they are reliable. Along with the filter's description, examples of data quality issues from application of the filter to nine months of archived PMU data are provided. The paper is intended to aid the reader in recognizing and properly addressing data quality issues in PMU data.« less

Protein Data Bank Japan (PDBj): updated user interfaces, resource description framework, analysis tools for large structures

PubMed Central

Kinjo, Akira R.; Bekker, Gert-Jan; Suzuki, Hirofumi; Tsuchiya, Yuko; Kawabata, Takeshi; Ikegawa, Yasuyo; Nakamura, Haruki

2017-01-01

The Protein Data Bank Japan (PDBj, http://pdbj.org), a member of the worldwide Protein Data Bank (wwPDB), accepts and processes the deposited data of experimentally determined macromolecular structures. While maintaining the archive in collaboration with other wwPDB partners, PDBj also provides a wide range of services and tools for analyzing structures and functions of proteins. We herein outline the updated web user interfaces together with RESTful web services and the backend relational database that support the former. To enhance the interoperability of the PDB data, we have previously developed PDB/RDF, PDB data in the Resource Description Framework (RDF) format, which is now a wwPDB standard called wwPDB/RDF. We have enhanced the connectivity of the wwPDB/RDF data by incorporating various external data resources. Services for searching, comparing and analyzing the ever-increasing large structures determined by hybrid methods are also described. PMID:27789697

MECDAS: A distributed data acquisition system for experiments at MAMI

NASA Astrophysics Data System (ADS)

Krygier, K. W.; Merle, K.

1994-02-01

For the coincidence experiments with the three spectrometer setup at MAMI an experiment control and data acquisition system has been built and was put successfully into final operation in 1992. MECDAS is designed as a distributed system using communication via Ethernet and optical links. As the front end, VME bus systems are used for real time purposes and direct hardware access via CAMAC, Fastbus or VMEbus. RISC workstations running UNIX are used for monitoring, data archiving and online and offline analysis of the experiment. MECDAS consists of several fixed programs and libraries, but large parts of readout and analysis can be configured by the user. Experiment specific configuration files are used to generate efficient and powerful code well adapted to special problems without additional programming. The experiment description is added to the raw collection of partially analyzed data to get self-descriptive data files.

Carbon monoxide effects on human ventricle action potential assessed by mathematical simulations

PubMed Central

Trenor, Beatriz; Cardona, Karen; Saiz, Javier; Rajamani, Sridharan; Belardinelli, Luiz; Giles, Wayne R.

2013-01-01

Carbon monoxide (CO) that is produced in a number of different mammalian tissues is now known to have significant effects on the cardiovascular system. These include: (i) vasodilation, (ii) changes in heart rate and strength of contractions, and (iii) modulation of autonomic nervous system input to both the primary pacemaker and the working myocardium. Excessive CO in the environment is toxic and can initiate or mediate life threatening cardiac rhythm disturbances. Recent reports link these ventricular arrhythmias to an increase in the slowly inactivating, or “late” component of the Na+ current in the mammalian heart. The main goal of this paper is to explore the basis of this pro-arrhythmic capability of CO by incorporating changes in CO-induced ion channel activity with intracellular signaling pathways in the mammalian heart. To do this, a quite well-documented mathematical model of the action potential and intracellular calcium transient in the human ventricular myocyte has been employed. In silico iterations based on this model provide a useful first step in illustrating the cellular electrophysiological consequences of CO that have been reported from mammalian heart experiments. Specifically, when the Grandi et al. model of the human ventricular action potential is utilized, and after the Na+ and Ca2+ currents in a single myocyte are modified based on the experimental literature, early after-depolarization (EAD) rhythm disturbances appear, and important elements of the underlying causes of these EADs are revealed/illustrated. Our modified mathematical model of the human ventricular action potential also provides a convenient digital platform for designing future experimental work and relating these changes in cellular cardiac electrophysiology to emerging clinical and epidemiological data on CO toxicity. PMID:24146650

Electrostatic interaction between an enzyme and electrodes in the electric double layer examined in a view of direct electron transfer-type bioelectrocatalysis.

PubMed

Sugimoto, Yu; Kitazumi, Yuki; Tsujimura, Seiya; Shirai, Osamu; Yamamoto, Masahiro; Kano, Kenji

2015-01-15

Effects of the electrode poential on the activity of an adsorbed enzyme has been examined by using copper efflux oxidase (CueO) as a model enzyme and by monitoring direct electron transfer (DET)-type bioelectrocatalysis of oxygen reduction. CueO adsorbed on bare Au electrodes at around the point of zero charge (E(pzc)) shows the highest DET activity, and the activity decreases as the adsorption potential (E(ad); at which the enzyme adsorbs) is far from E(pzc). We propose a model to explain the phenomena in which the electrostatic interaction between the enzyme and electrodes in the electric double layer affects the orientation and the stability of the adsorbed enzyme. The self-assembled monolayer of butanethiol on Au electrodes decreases the electric field in the outside of the inner Helmholtz plane and drastically diminishes the E(ad) dependence of the DET activity of CueO. When CueO is adsorbed on bare Au electrodes under open circuit potential and then is held at hold potentials (E(ho)) more positive than E(pzc), the DET activity of the CueO rapidly decreases with the hold time. The strong electric field with positive surface charge density on the metallic electrode (σ(M)) leads to fatal denaturation of the adsorbed CueO. Such denaturation effect is not so serious at E(ho)

Controlling equine influenza: policy networks and decision-making during the 2007 Australian equine influenza outbreak.

PubMed

Schemann, K; Gillespie, J A; Toribio, J-A L M L; Ward, M P; Dhand, N K

2014-10-01

Rapid, evidence-based decision-making is critical during a disease outbreak response; however, compliance by stakeholders is necessary to ensure that such decisions are effective - especially if the response depends on voluntary action. This mixed method study evaluated technical policy decision-making processes during the 2007 outbreak of equine influenza in Australia by identifying and analysing the stakeholder network involved and the factors driving policy decision-making. The study started with a review of the outbreak literature and published policy documents. This identified six policy issues regarding policy modifications or differing interpretations by different state agencies. Data on factors influencing the decision-making process for these six issues and on stakeholder interaction were collected using a pre-tested, semi-structured questionnaire. Face-to-face interviews were conducted with 24 individuals representing 12 industry and government organizations. Quantitative data were analysed using social network analysis. Qualitative data were coded and patterns matched to test a pre-determined general theory using a method called theory-oriented process-tracing. Results revealed that technical policy decisions were framed by social, political, financial, strategic and operational considerations. Industry stakeholders had influence through formal pre-existing channels, yet specific gaps in stakeholder interaction were overcome by reactive alliances formed during the outbreak response but outside the established system. Overall, the crisis management system and response were seen as positive, and 75-100% of individuals interviewed were supportive of, had interest in and considered the outcome as good for the majority of policy decisions, yet only 46-75% of those interviewed considered that they had influence on these decisions. Training to increase awareness and knowledge of emergency animal diseases (EADs) and response systems will improve stakeholder participation in emergency disease management and preparedness for future EAD incursions. © 2012 Blackwell Verlag GmbH.

A density functional theory computational study of adsorption of Di-Meta-Cyano Azobenzene molecules on Si (111) surfaces

NASA Astrophysics Data System (ADS)

Motevalli, Benyamin; Taherifar, Neda; Wu, Bisheng; Tang, Wenxin; Liu, Jefferson Zhe

2017-11-01

The adsorption of di-meta-cyano azobenzene (DMC) cis and trans isomers on non-passivated and passivated Si (111) (7 × 7) surfaces is studied using density functional theory (DFT) calculations. Our results reveal that on the non-passivated surface the 12 Si adatoms are accessible to form chemical bonds with DMC molecules. Interestingly, the trans isomer forms two chemical bonds near the corner hole atom in Si (111) (7 × 7) surface, which is not observed in the widely studied metallic surfaces. The DMC isomers show significant structural distortion in the chemisorption case. The strong chemical bonds (and high bonding energy) could be detrimental to conformation switching between these two isomers under external stimuli. The physisorption case is also examined. Monte Carlo (MC) simulations with empirical force fields were employed to search about 106 different adsorption positions and DMC molecule orientations to identify the stable adsorption sites (up to six). The DFT-PBE and DFT-D2 calculations were then carried out to obtain the relaxed atomistic structures and accurate adsorption energy. We find that it is imperative to take van der Waals (vdW) interaction into account in DFT calculations. Our results show that the adsorption sites generally are encompassed by either the Si adatoms or the passivated H atoms, which could enhance the long-range dispersion interaction between DMC molecules and Si surfaces. The molecular structures of both isomers remain unchanged compared with gas phase. The obtained adsorption energy results ΔEads are moderate (0.2-0.8 eV). At some adsorption sites on the passivated surface, both isomers have similar moderate ΔEads (0.4-0.6 eV), implying promises of molecular switching that should be examined in experiments.

Emission of Volatile Compounds from Apple Plants Infested with Pandemis heparana Larvae, Antennal Response of Conspecific Adults, and Preliminary Field Trial.

PubMed

Giacomuzzi, Valentino; Cappellin, Luca; Khomenko, Iuliia; Biasioli, Franco; Schütz, Stefan; Tasin, Marco; Knight, Alan L; Angeli, Sergio

2016-12-01

This study investigated the volatile emission from apple (Malus x domestica Borkh., cv. Golden Delicious) foliage that was either intact, mechanically-damaged, or exposed to larval feeding by Pandemis heparana (Denis and Schiffermüller) (Lepidoptera: Tortricidae). Volatiles were collected by closed-loop-stripping-analysis and characterized by gas chromatography-mass spectrometry in three time periods: after 1 h and again 24 and 48 h later. Volatiles for all treatments also were monitored continuously over a 72-h period by the use of proton transfer reaction - time of flight-mass spectrometry (PTR-ToF-MS). In addition, the volatile samples were analyzed by gas chromatography-electroantennographic detection (GC-EAD) using male and female antennae of P. heparana. Twelve compounds were detected from intact foliage compared with 23 from mechanically-damaged, and 30 from P. heparana-infested foliage. Interestingly, six compounds were released only by P. heparana-infested foliage. The emission dynamics of many compounds measured by PTR-ToF-MS showed striking differences according to the timing of herbivory and the circadian cycle. For example, the emission of green leaf volatiles began shortly after the start of herbivory, and increased over time independently from the light-dark cycle. Conversely, the emission of terpenes and aromatic compounds showed a several-hour delay in response to herbivory, and followed a diurnal rhythm. Methanol was the only identified volatile showing a nocturnal rhythm. Consistent GC-EAD responses were found for sixteen compounds, including five aromatic ones. A field trial in Sweden demonstrated that benzyl alcohol, 2-phenylethanol, phenylacetonitrile, and indole lures placed in traps were not attractive to Pandemis spp. adults, but 2-phenylethanol and phenylacetonitrile when used in combination with acetic acid were attractive to both sexes.

Trends in statistical methods in articles published in Archives of Plastic Surgery between 2012 and 2017.

PubMed

Han, Kyunghwa; Jung, Inkyung

2018-05-01

This review article presents an assessment of trends in statistical methods and an evaluation of their appropriateness in articles published in the Archives of Plastic Surgery (APS) from 2012 to 2017. We reviewed 388 original articles published in APS between 2012 and 2017. We categorized the articles that used statistical methods according to the type of statistical method, the number of statistical methods, and the type of statistical software used. We checked whether there were errors in the description of statistical methods and results. A total of 230 articles (59.3%) published in APS between 2012 and 2017 used one or more statistical method. Within these articles, there were 261 applications of statistical methods with continuous or ordinal outcomes, and 139 applications of statistical methods with categorical outcome. The Pearson chi-square test (17.4%) and the Mann-Whitney U test (14.4%) were the most frequently used methods. Errors in describing statistical methods and results were found in 133 of the 230 articles (57.8%). Inadequate description of P-values was the most common error (39.1%). Among the 230 articles that used statistical methods, 71.7% provided details about the statistical software programs used for the analyses. SPSS was predominantly used in the articles that presented statistical analyses. We found that the use of statistical methods in APS has increased over the last 6 years. It seems that researchers have been paying more attention to the proper use of statistics in recent years. It is expected that these positive trends will continue in APS.

CHAWS user`s guide: System description and standard operating procedures, Lexington-Blue Grass Army Depot

DOE Office of Scientific and Technical Information (OSTI.GOV)

Martins, S.A.; Shinn, J.H.

1993-05-01

The Chemical Hazard Warning System (CHAWS) is designed to collect meteorological data and to display, in real time, the dispersion of hazardous chemicals that may result from an accidental release. Meteorological sensors have been placed strategically around the Lexington-Blue Grass Army Depot and are used to calculate direction and hazard distance for the release. Based on these data, arrows depicting the release direction and distance traveled are graphically displayed on a computer screen showing a site map of the facility. The objectives of CHAWS are as follows: To determine the trajectory of the center of mass of released material frommore » the measured wind field; to calculate the dispersion of the released material based on the measured lateral turbulence intensity (sigma theta); to determine the height of the mixing zone by measurement of the inversion height and wind profiles up to an altitude of about 1 km at sites that have SODAR units installed; to archive meteorological data for potential use in climatological descriptions for emergency planning; to archive air-quality data for preparation of compliance reports; and to provide access to the data for near real time hazard analysis purposes. CHAWS sites are located at the Pine Bluff Arsenal, Arkansas, Edgewood area of Aberdeen Proving Ground, Maryland, Tooele Depot, Utah, Lexington-Blue Grass Depot, Kentucky, and Johnston Island in the Pacific. The systems vary between sites with different features and various types of hardware. The basic system, however, is the same. Nonetheless, we have tailored the manuals to the equipment found at each site.« less

WIFIRE Data Model and Catalog for Wildfire Data and Tools

NASA Astrophysics Data System (ADS)

Altintas, I.; Crawl, D.; Cowart, C.; Gupta, A.; Block, J.; de Callafon, R.

2014-12-01

The WIFIRE project (wifire.ucsd.edu) is building an end-to-end cyberinfrastructure for real-time and data-driven simulation, prediction and visualization of wildfire behavior. WIFIRE may be used by wildfire management authorities in the future to predict wildfire rate of spread and direction, and assess the effectiveness of high-density sensor networks in improving fire and weather predictions. WIFIRE has created a data model for wildfire resources including sensed and archived data, sensors, satellites, cameras, modeling tools, workflows and social information including Twitter feeds. This data model and associated wildfire resource catalog includes a detailed description of the HPWREN sensor network, SDG&E's Mesonet, and NASA MODIS. In addition, the WIFIRE data-model describes how to integrate the data from multiple heterogeneous sources to provide detailed fire-related information. The data catalog describes 'Observables' captured by each instrument using multiple ontologies including OGC SensorML and NASA SWEET. Observables include measurements such as wind speed, air temperature, and relative humidity, as well as their accuracy and resolution. We have implemented a REST service for publishing to and querying from the catalog using Web Application Description Language (WADL). We are creating web-based user interfaces and mobile device Apps that use the REST interface for dissemination to wildfire modeling community and project partners covering academic, private, and government laboratories while generating value to emergency officials and the general public. Additionally, the Kepler scientific workflow system is instrumented to interact with this data catalog to access real-time streaming and archived wildfire data and stream it into dynamic data-driven wildfire models at scale.

Habitat diversity in the Northeastern Gulf of Mexico: Selected video clips from the Gulfstream Natural Gas Pipeline digital archive

USGS Publications Warehouse

Raabe, Ellen A.; D'Anjou, Robert; Pope, Domonique K.; Robbins, Lisa L.

2011-01-01

This project combines underwater video with maps and descriptions to illustrate diverse seafloor habitats from Tampa Bay, Florida, to Mobile Bay, Alabama. A swath of seafloor was surveyed with underwater video to 100 meters (m) water depth in 1999 and 2000 as part of the Gulfstream Natural Gas System Survey. The U.S. Geological Survey (USGS) in St. Petersburg, Florida, in cooperation with Eckerd College and the Florida Department of Environmental Protection (FDEP), produced an archive of analog-to-digital underwater movies. Representative clips of seafloor habitats were selected from hundreds of hours of underwater footage. The locations of video clips were mapped to show the distribution of habitat and habitat transitions. The numerous benthic habitats in the northeastern Gulf of Mexico play a vital role in the region's economy, providing essential resources for tourism, natural gas, recreational water sports (fishing, boating, scuba diving), materials, fresh food, energy, a source of sand for beach renourishment, and more. These submerged natural resources are important to the economy but are often invisible to the general public. This product provides a glimpse of the seafloor with sample underwater video, maps, and habitat descriptions. It was developed to depict the range and location of seafloor habitats in the region but is limited by depth and by the survey track. It should not be viewed as comprehensive, but rather as a point of departure for inquiries and appreciation of marine resources and seafloor habitats. Further information is provided in the Resources section.

Experiences with making diffraction image data available: what metadata do we need to archive?

PubMed

Kroon-Batenburg, Loes M J; Helliwell, John R

2014-10-01

Recently, the IUCr (International Union of Crystallography) initiated the formation of a Diffraction Data Deposition Working Group with the aim of developing standards for the representation of raw diffraction data associated with the publication of structural papers. Archiving of raw data serves several goals: to improve the record of science, to verify the reproducibility and to allow detailed checks of scientific data, safeguarding against fraud and to allow reanalysis with future improved techniques. A means of studying this issue is to submit exemplar publications with associated raw data and metadata. In a recent study of the binding of cisplatin and carboplatin to histidine in lysozyme crystals under several conditions, the possible effects of the equipment and X-ray diffraction data-processing software on the occupancies and B factors of the bound Pt compounds were compared. Initially, 35.3 GB of data were transferred from Manchester to Utrecht to be processed with EVAL. A detailed description and discussion of the availability of metadata was published in a paper that was linked to a local raw data archive at Utrecht University and also mirrored at the TARDIS raw diffraction data archive in Australia. By making these raw diffraction data sets available with the article, it is possible for the diffraction community to make their own evaluation. This led to one of the authors of XDS (K. Diederichs) to re-integrate the data from crystals that supposedly solely contained bound carboplatin, resulting in the analysis of partially occupied chlorine anomalous electron densities near the Pt-binding sites and the use of several criteria to more carefully assess the diffraction resolution limit. General arguments for archiving raw data, the possibilities of doing so and the requirement of resources are discussed. The problems associated with a partially unknown experimental setup, which preferably should be available as metadata, is discussed. Current thoughts on data compression are summarized, which could be a solution especially for pixel-device data sets with fine slicing that may otherwise present an unmanageable amount of data.

An archiving system for Planetary Mapping Data - Availability of derived information and knowledge in Planetary Science!

NASA Astrophysics Data System (ADS)

Nass, A.

2017-12-01

Since the late 1950s a huge number of planetary missions started to explore our solar system. The data resulting from this robotic exploration and remote sensing varies in data type, resolution and target. After data preprocessing, and referencing, the released data are available for the community on different portals and archiving systems, e.g. PDS or PSA. One major usage for these data is mapping, i.e. the extraction and filtering of information by combining and visualizing different kind of base data. Mapping itself is conducted either for mission planning (e.g. identification of landing site) or fundamental research (e.g. reconstruction of surface). The mapping results for mission planning are directly managed within the mission teams. The derived data for fundamental research - also describable as maps, diagrams, or analysis results - are mainly project-based and exclusively available in scientific papers. Within the last year, first steps have been taken to ensure a sustainable use of these derived data by finding an archiving system comparable to the data portals, i.e. reusable, well-documented, and sustainable. For the implementation three tasks are essential. Two tasks have been treated in the past 1. Comparability and interoperability has been made possible by standardized recommendations for visual, textual, and structural description of mapping data. 2. Interoperability between users, information- and graphic systems is possible by templates and guidelines for digital GIS-based mapping. These two steps are adapted e.g. within recent mapping projects for the Dawn mission. The third task hasn`t been implemented thus far: Establishing an easily detectable and accessible platform that holds already acquired information and published mapping results for future investigations or mapping projects. An archive like this would support the scientific community significantly by a constant rise of knowledge and understanding based on recent discussions within Information Science and Management, and Data Warehousing. This contribution describes the necessary map archive components that have to be considered for an efficient establishment and user-oriented accessibility. It will be described how already existing developments could be used, and which components will have to be developed yet.

VO for Education: Archive Prototype

NASA Astrophysics Data System (ADS)

Ramella, M.; Iafrate, G.; De Marco, M.; Molinaro, M.; Knapic, C.; Smareglia, R.; Cepparo, F.

2014-05-01

The number of remote control telescopes dedicated to education is increasing in many countries, leading to correspondingly larger and larger amount of stored educational data that are usually available only to local observers. Here we present the project for a new infrastructure that will allow teachers using educational telescopes to archive their data and easily publish them within the Virtual Observatory (VO) avoiding the complexity of professional tools. Students and teachers anywhere will be able to access these data with obvious benefits for the realization of grander scale collaborative projects. Educational VO data will also be an important resource for teachers not having direct access to any educational telescopes. We will use the educational telescope at our observatory in Trieste as a prototype for the future VO educational data archive resource. The publishing infrastructure will include: user authentication, content and curation validation, data validation and ingestion, VO compliant resource generation. All of these parts will be performed by means of server side applications accessible through a web graphical user interface (web GUI). Apart from user registration, that will be validated by a natural person responsible for the archive (after having verified the reliability of the user and inspected one or more test files), all the subsequent steps will be automated. This means that at the very first data submission through the webGUI, a complete resource including archive and published VO service will be generated, ready to be registered to the VO. The efforts required to the registered user will consist only in describing herself/himself at registration step and submitting the data she/he selects for publishing after each observation sessions. The infrastructure will be file format independent and the underlying data model will use a minimal set of standard VO keywords, some of which will be specific for outreach and education, possibly including VO field identification (astronomy, planetary science, solar physics). The VO published resource description will be suggested such as to allow selective access to educational data by VO aware tools, differentiating them from professional data while treating them with the same procedures, protocols and tools. The whole system will be very flexible, scalable and with the objective to leave as less work as possible to humans.

Reproducible computational biology experiments with SED-ML--the Simulation Experiment Description Markup Language.

PubMed

Waltemath, Dagmar; Adams, Richard; Bergmann, Frank T; Hucka, Michael; Kolpakov, Fedor; Miller, Andrew K; Moraru, Ion I; Nickerson, David; Sahle, Sven; Snoep, Jacky L; Le Novère, Nicolas

2011-12-15

The increasing use of computational simulation experiments to inform modern biological research creates new challenges to annotate, archive, share and reproduce such experiments. The recently published Minimum Information About a Simulation Experiment (MIASE) proposes a minimal set of information that should be provided to allow the reproduction of simulation experiments among users and software tools. In this article, we present the Simulation Experiment Description Markup Language (SED-ML). SED-ML encodes in a computer-readable exchange format the information required by MIASE to enable reproduction of simulation experiments. It has been developed as a community project and it is defined in a detailed technical specification and additionally provides an XML schema. The version of SED-ML described in this publication is Level 1 Version 1. It covers the description of the most frequent type of simulation experiments in the area, namely time course simulations. SED-ML documents specify which models to use in an experiment, modifications to apply on the models before using them, which simulation procedures to run on each model, what analysis results to output, and how the results should be presented. These descriptions are independent of the underlying model implementation. SED-ML is a software-independent format for encoding the description of simulation experiments; it is not specific to particular simulation tools. Here, we demonstrate that with the growing software support for SED-ML we can effectively exchange executable simulation descriptions. With SED-ML, software can exchange simulation experiment descriptions, enabling the validation and reuse of simulation experiments in different tools. Authors of papers reporting simulation experiments can make their simulation protocols available for other scientists to reproduce the results. Because SED-ML is agnostic about exact modeling language(s) used, experiments covering models from different fields of research can be accurately described and combined.

SPSS and SAS procedures for estimating indirect effects in simple mediation models.

PubMed

Preacher, Kristopher J; Hayes, Andrew F

2004-11-01

Researchers often conduct mediation analysis in order to indirectly assess the effect of a proposed cause on some outcome through a proposed mediator. The utility of mediation analysis stems from its ability to go beyond the merely descriptive to a more functional understanding of the relationships among variables. A necessary component of mediation is a statistically and practically significant indirect effect. Although mediation hypotheses are frequently explored in psychological research, formal significance tests of indirect effects are rarely conducted. After a brief overview of mediation, we argue the importance of directly testing the significance of indirect effects and provide SPSS and SAS macros that facilitate estimation of the indirect effect with a normal theory approach and a bootstrap approach to obtaining confidence intervals, as well as the traditional approach advocated by Baron and Kenny (1986). We hope that this discussion and the macros will enhance the frequency of formal mediation tests in the psychology literature. Electronic copies of these macros may be downloaded from the Psychonomic Society's Web archive at www.psychonomic.org/archive/.

Disaster management and the critical thinking skills of local emergency managers: correlations with age, gender, education, and years in occupation.

PubMed

Peerbolte, Stacy L; Collins, Matthew Lloyd

2013-01-01

Emergency managers must be able to think critically in order to identify and anticipate situations, solve problems, make judgements and decisions effectively and efficiently, and assume and manage risk. Heretofore, a critical thinking skills assessment of local emergency managers had yet to be conducted that tested for correlations among age, gender, education, and years in occupation. An exploratory descriptive research design, using the Watson-Glaser Critical Thinking Appraisal-Short Form (WGCTA-S), was employed to determine the extent to which a sample of 54 local emergency managers demonstrated the critical thinking skills associated with the ability to assume and manage risk as compared to the critical thinking scores of a group of 4,790 peer-level managers drawn from an archival WGCTA-S database. This exploratory design suggests that the local emergency managers, surveyed in this study, had lower WGCTA-S critical thinking scores than their equivalents in the archival database with the exception of those in the high education and high experience group. © 2013 The Author(s). Journal compilation © Overseas Development Institute, 2013.

On-line access to remote sensing data with the satellite-data information system (ISIS)

NASA Astrophysics Data System (ADS)

Strunz, G.; Lotz-Iwen, H.-J.

1994-08-01

The German Remote Sensing Data Center (DFD) is developing the satellite-data information system ISIS as central interface for users to access Earth observation data. ISIS has been designed to support international scientific research as well as operational applications by offering online database access via public networks, and is integrated in the international activities dedicated to catalogue and archive interoperability. A prototype of ISIS is already in use within the German Processing and Archiving Facility for ERS-1 for the storage and retrieval of digital SAR quicklook products and for the Radarmap of Germany. An operational status of the system is envisaged for the launch of ERS-2. The paper in hand describes the underlying concepts of ISIS and the recent state of realization. It explains the overall structure of the system and the functionality of each of its components. Emphasis is put on the description of the advisory system, the catalogue retrieval, and the online access and transfer of image data. Finally, the integration into a future global environmental data network is outlined.

Big heart data: advancing health informatics through data sharing in cardiovascular imaging.

PubMed

Suinesiaputra, Avan; Medrano-Gracia, Pau; Cowan, Brett R; Young, Alistair A

2015-07-01

The burden of heart disease is rapidly worsening due to the increasing prevalence of obesity and diabetes. Data sharing and open database resources for heart health informatics are important for advancing our understanding of cardiovascular function, disease progression and therapeutics. Data sharing enables valuable information, often obtained at considerable expense and effort, to be reused beyond the specific objectives of the original study. Many government funding agencies and journal publishers are requiring data reuse, and are providing mechanisms for data curation and archival. Tools and infrastructure are available to archive anonymous data from a wide range of studies, from descriptive epidemiological data to gigabytes of imaging data. Meta-analyses can be performed to combine raw data from disparate studies to obtain unique comparisons or to enhance statistical power. Open benchmark datasets are invaluable for validating data analysis algorithms and objectively comparing results. This review provides a rationale for increased data sharing and surveys recent progress in the cardiovascular domain. We also highlight the potential of recent large cardiovascular epidemiological studies enabling collaborative efforts to facilitate data sharing, algorithms benchmarking, disease modeling and statistical atlases.

Eponymous Instruments in Orthopaedic Surgery

PubMed Central

Buraimoh, M. Ayodele; Liu, Jane Z.; Sundberg, Stephen B.; Mott, Michael P.

2017-01-01

Abstract Every day surgeons call for instruments devised by surgeon trailblazers. This article aims to give an account of commonly used eponymous instruments in orthopaedic surgery, focusing on the original intent of their designers in order to inform how we use them today. We searched PubMed, the archives of longstanding medical journals, Google, the Internet Archive, and the HathiTrust Digital Library for information regarding the inventors and the developments of 7 instruments: the Steinmann pin, Bovie electrocautery, Metzenbaum scissors, Freer elevator, Cobb periosteal elevator, Kocher clamp, and Verbrugge bone holding forceps. A combination of ingenuity, necessity, circumstance and collaboration produced the inventions of the surgical tools numbered in our review. In some cases, surgical instruments were improvements of already existing technologies. The indications and applications of the orthopaedic devices have changed little. Meanwhile, instruments originally developed for other specialties have been adapted for our use. Although some argue for a transition from eponymous to descriptive terms in medicine, there is value in recognizing those who revolutionized surgical techniques and instrumentation. Through history, we have an opportunity to be inspired and to better understand our tools. PMID:28852360

DOE Office of Scientific and Technical Information (OSTI.GOV)

Palanisamy, Giri

The U.S. Department of Energy (DOE)’s Atmospheric Radiation Measurement (ARM) Climate Research Facility performs routine in situ and remote-sensing observations to provide a detailed and accurate description of the Earth atmosphere in diverse climate regimes. The result is a huge archive of diverse data sets containing observational and derived data, currently accumulating at a rate of 30 terabytes (TB) of data and 150,000 different files per month (http://www.archive.arm.gov/stats/). Continuing the current processing while scaling this to even larger sizes is extremely important to the ARM Facility and requires consistent metadata and data standards. The standards described in this document willmore » enable development of automated analysis and discovery tools for the ever growing data volumes. It will enable consistent analysis of the multiyear data, allow for development of automated monitoring and data health status tools, and allow future capabilities of delivering data on demand that can be tailored explicitly for the user needs. This analysis ability will only be possible if the data follows a minimum set of standards. This document proposes a hierarchy of required and recommended standards.« less

Earth-System Scales of Biodiversity Variability in Shallow Continental Margin Seafloor Ecosystems

NASA Astrophysics Data System (ADS)

Moffitt, S. E.; White, S. M.; Hill, T. M.; Kennett, J.

2015-12-01

High-resolution paleoceanographic sedimentary sequences allow for the description of ecosystem sensitivity to earth-system scales of climate and oceanographic change. Such archives from Santa Barbara Basin, California record the ecological consequences to seafloor ecosystems of climate-forced shifts in the California Current Oxygen Minimum Zone (OMZ). Here we use core MV0508-20JPC dated to 735,000±5,000 years ago (Marine Isotope Stage 18) as a "floating window" of millennial-scale ecological variability. For this investigation, previously published archives of planktonic δ18O (Globigerina bulloides) record stadial and interstadial oscillations in surface ocean temperature. Core MV0508-20JPC is an intermittently laminated archive, strongly influenced by the California Current OMZ, with continuously preserved benthic foraminifera and discontinuously preserved micro-invertebrates, including ophiuroids, echinoderms, ostracods, gastropods, bivalves and scaphopods. Multivariate statistical approaches, such as ordinations and cluster analyses, describe climate-driven changes in both foraminiferal and micro-invertebrate assemblages. Statistical ordinations illustrate that the shallow continental margin seafloor underwent predictable phase-shifts in oxygenation and biodiversity across stadial and interstadial events. A narrow suite of severely hypoxic taxa characterized foraminiferal communities from laminated intervals, including Bolivina tumida, Globobulimina spp., and Nonionella stella. Foraminiferal communities from bioturbated intervals are diverse and >60% similar to each other, and they are associated with echinoderm, ostracod and mollusc fossils. As with climate shifts in the latest Quaternary, there is a sensitive benthic ecosystem response in mid-Pleistocene continental margins to climatically related changes in OMZ strength.

Candidate Insect Repellent AI3-35713-aGa N-Pentylvaleramide

DTIC Science & Technology

1976-10-19

0 Io -44 0 0 ON . w *0. 4) L0 0 ~ -- 0t, M- N 41 M , y ) *4Ur 0 f E0 4) MN 4) O.* r U 4J404 Ul~ r, eo 0 r. a.O~U f- n AN 1. ) 41$44 r. 4 0 -. ) MJ N ...TOPICAL HAZARD EVALUATION . , OF CANDIDATE INSECT REPELLENT AI3-35713-aGa N -PENTYLVALERAMIDE STUDY NO. 51-0802-77 AUGUST 1975 - AUGUST 1976 Approved...CLASSIFICATION DO’ THIS PAGE (Wlhet Der. Znftro* REPORT DOCUMENTATION PAGE EA~D N RM 1. REPORT NUMBER 2. GOVT ACCESSION No. 3. RECIPIENT’S CATALOG NUMBER 51

The Longhorn Array Database (LAD): An Open-Source, MIAME compliant implementation of the Stanford Microarray Database (SMD)

PubMed Central

Killion, Patrick J; Sherlock, Gavin; Iyer, Vishwanath R

2003-01-01

Background The power of microarray analysis can be realized only if data is systematically archived and linked to biological annotations as well as analysis algorithms. Description The Longhorn Array Database (LAD) is a MIAME compliant microarray database that operates on PostgreSQL and Linux. It is a fully open source version of the Stanford Microarray Database (SMD), one of the largest microarray databases. LAD is available at Conclusions Our development of LAD provides a simple, free, open, reliable and proven solution for storage and analysis of two-color microarray data. PMID:12930545

Formalized description and construction of semantic dictionary of graphic-text spatial relationship

NASA Astrophysics Data System (ADS)

Sun, Yizhong; Xue, Xiaolei; Zhao, Xiaoqin

2008-10-01

Graphic and text are two major elements in exhibiting of the results of urban planning and land administration. In combination, they convey the complex relationship resulting from spatial analysis and decision-making. Accurately interpreting and representing these relationships are important steps towards an intelligent GIS for urban planning. This paper employs concept-hierarchy-tree to formalize graphic-text relationships through a framework of spatial object lexicon, spatial relationship lexicon, restriction lexicon, applied pattern base, and word segmentation rule base. The methodology is further verified and shown effective on several urban planning archives.

The NASA ADS Abstract Service and the Distributed Astronomy Digital Library [and] Project Soup: Comparing Evaluations of Digital Collection Efforts [and] Cross-Organizational Access Management: A Digital Library Authentication and Authorization Architecture [and] BibRelEx: Exploring Bibliographic Databases by Visualization of Annotated Content-based Relations [and] Semantics-Sensitive Retrieval for Digital Picture Libraries [and] Encoded Archival Description: An Introduction and Overview.

ERIC Educational Resources Information Center

Kurtz, Michael J.; Eichorn, Guenther; Accomazzi, Alberto; Grant, Carolyn S.; Demleitner, Markus; Murray, Stephen S.; Jones, Michael L. W.; Gay, Geri K.; Rieger, Robert H.; Millman, David; Bruggemann-Klein, Anne; Klein, Rolf; Landgraf, Britta; Wang, James Ze; Li, Jia; Chan, Desmond; Wiederhold, Gio; Pitti, Daniel V.

1999-01-01

Includes six articles that discuss a digital library for astronomy; comparing evaluations of digital collection efforts; cross-organizational access management of Web-based resources; searching scientific bibliographic databases based on content-based relations between documents; semantics-sensitive retrieval for digital picture libraries; and…

Improved Data Access From the Northern California Earthquake Data Center

NASA Astrophysics Data System (ADS)

Neuhauser, D.; Oppenheimer, D.; Zuzlewski, S.; Klein, F.; Jensen, E.; Gee, L.; Murray, M.; Romanowicz, B.

2002-12-01

The NCEDC is a joint project of the UC Berkeley Seismological Laboratory and the USGS Menlo Park to provide a long-term archive and distribution center for geophysical data for northern California. Most data are available via the Web at http://quake.geo.berkeley.edu and research accounts are available for access to specialized datasets. Current efforts continue to expand the available datasets, enhance distribution methods, and to provide rapid access to all datasets. The NCEDC archives continuous and event-based seismic and geophysical time-series data from the BDSN, the USGS NCSN, the UNR Seismic Network, the Parkfield HRSN, and the Calpine/Unocal Geysers network. In collaboration with the USGS, the NCEDC has archived a total of 887 channels from 139 sites of the "USGS low-frequency" geophysical network (UL), including data from strainmeters, creep meters, magnetometers, water well levels, and tiltmeters. There are 336 active continuous data channels that are updated at the NCEDC on a daily basis. Geodetic data from the BARD network of over 40 continuously recording GPS sites are archived at the NCEDC in both raw and RINEX format. The NCEDC is the primary archive for survey-mode GPS and other geodetic data collected in northern California by the USGS, universities, and other agencies. All of the BARD data and GPS data archived from USGS Menlo Park surveys are now available through the GPS Seamless Archive Centers (GSAC), and by FTP directly from the NCEDC. Virtually all time-series data at the NCEDC are now available in SEED with complete instrument responses. Assembling, verifying, and maintaining the response information for these networks is a huge task, and is accomplished through the collaborative efforts of the NCEDC and the contributing agencies. Until recently, the NCSN waveform data were available only through research accounts and special request methods due to incomplete instrument responses. In the last year, the USGS compiled the necessary descriptions for for both historic and current NCSN instrumentation. The NCEDC and USGS jointly developed a procedure to create and maintain the hardware attributes and instrument responses at the NCEDC for the 3500 NCSN channels. As a result, the NCSN waveform data can now be distributed in SEED format. The NCEDC provides access to waveform data through Web forms, email requests, and programming interfaces. The SeismiQuery Web interface provides information about data holdings. NetDC allows users to retrieve inventory information, instrument responses, and waveforms in SEED format. STP provides both a Web and programming interface to retrieve data in SEED or other user-friendly formats. Through the newly formed California Integrated Seismic Network, we are working with the SCEDC to provide unified access to California earthquake data.

OceanNOMADS: Real-time and retrospective access to operational U.S. ocean prediction products

NASA Astrophysics Data System (ADS)

Harding, J. M.; Cross, S. L.; Bub, F.; Ji, M.

2011-12-01

The National Oceanic and Atmospheric Administration (NOAA) National Operational Model Archive and Distribution System (NOMADS) provides both real-time and archived atmospheric model output from servers at the National Centers for Environmental Prediction (NCEP) and National Climatic Data Center (NCDC) respectively (http://nomads.ncep.noaa.gov/txt_descriptions/marRutledge-1.pdf). The NOAA National Ocean Data Center (NODC) with NCEP is developing a complementary capability called OceanNOMADS for operational ocean prediction models. An NCEP ftp server currently provides real-time ocean forecast output (http://www.opc.ncep.noaa.gov/newNCOM/NCOM_currents.shtml) with retrospective access through NODC. A joint effort between the Northern Gulf Institute (NGI; a NOAA Cooperative Institute) and the NOAA National Coastal Data Development Center (NCDDC; a division of NODC) created the developmental version of the retrospective OceanNOMADS capability (http://www.northerngulfinstitute.org/edac/ocean_nomads.php) under the NGI Ecosystem Data Assembly Center (EDAC) project (http://www.northerngulfinstitute.org/edac/). Complementary funding support for the developmental OceanNOMADS from U.S. Integrated Ocean Observing System (IOOS) through the Southeastern University Research Association (SURA) Model Testbed (http://testbed.sura.org/) this past year provided NODC the analogue that facilitated the creation of an NCDDC production version of OceanNOMADS (http://www.ncddc.noaa.gov/ocean-nomads/). Access tool development and storage of initial archival data sets occur on the NGI/NCDDC developmental servers with transition to NODC/NCCDC production servers as the model archives mature and operational space and distribution capability grow. Navy operational global ocean forecast subsets for U.S waters comprise the initial ocean prediction fields resident on the NCDDC production server. The NGI/NCDDC developmental server currently includes the Naval Research Laboratory Inter-America Seas Nowcast/Forecast System over the Gulf of Mexico from 2004-Mar 2011, the operational Naval Oceanographic Office (NAVOCEANO) regional USEast ocean nowcast/forecast system from early 2009 to present, and the NAVOCEANO operational regional AMSEAS (Gulf of Mexico/Caribbean) ocean nowcast/forecast system from its inception 25 June 2010 to present. AMSEAS provided one of the real-time ocean forecast products accessed by NOAA's Office of Response and Restoration from the NGI/NCDDC developmental OceanNOMADS during the Deep Water Horizon oil spill last year. The developmental server also includes archived, real-time Navy coastal forecast products off coastal Japan in support of U.S./Japanese joint efforts following the 2011 tsunami. Real-time NAVOCEANO output from regional prediction systems off Southern California and around Hawaii, currently available on the NCEP ftp server, are scheduled for archival on the developmental OceanNOMADS by late 2011 along with the next generation Navy/NOAA global ocean prediction output. Accession and archival of additional regions is planned as server capacities increase.

Real Option Cost Vulnerability Analysis of Electrical Infrastructure

NASA Astrophysics Data System (ADS)

Prime, Thomas; Knight, Phil

2015-04-01

Critical infrastructure such as electricity substations are vulnerable to various geo-hazards that arise from climate change. These geo-hazards range from increased vegetation growth to increased temperatures and flood inundation. Of all the identified geo-hazards, coastal flooding has the greatest impact, but to date has had a low probability of occurring. However, in the face of climate change, coastal flooding is likely to occur more often due to extreme water levels being experienced more frequently due to sea-level rise (SLR). Knowing what impact coastal flooding will have now and in the future on critical infrastructure such as electrical substations is important for long-term management. Using a flood inundation model, present day and future flood events have been simulated, from 1 in 1 year events up to 1 in 10,000 year events. The modelling makes an integrated assessment of impact by using sea-level and surge to simulate a storm tide. The geographical area the model covers is part of the Northwest UK coastline with a range of urban and rural areas. The ensemble of flood maps generated allows the identification of critical infrastructure exposed to coastal flooding. Vulnerability has be assessed using an Estimated Annual Damage (EAD) value. Sampling SLR annual probability distributions produces a projected "pathway" for SLR up to 2100. EAD is then calculated using a relationship derived from the flood model. Repeating the sampling process allows a distribution of EAD up to 2100 to be produced. These values are discounted to present day values using an appropriate discount rate. If the cost of building and maintain defences is also removed from this a Net Present Value (NPV) of building the defences can be calculated. This distribution of NPV can be used as part of a cost modelling process involving Real Options, A real option is the right but not obligation to undertake investment decisions. In terms of investment in critical infrastructure resilience this means that a real option can be deferred or exercised depending on the climate future that has been realised. The real option value is defined as the maximum positive NPV value that is found across the range of potential SLR "futures". Real Options add value in that flood defences may not be built when there is real value in doing so. The cost modelling output is in the form of an accessible database that has detailed real option values varying spatially across the model domain (for each critical infrastructure) and temporally up to 2100. The analysis has shown that in 2100, 8.2% of the substations analysed have a greater than a 1 in 2 chance of exercising the real option to build flood defences against coastal flooding. The cost modelling tool and flood maps that have been developed will help stakeholders in deciding where and when to invest in mitigating against coastal flooding.

Soil archives of a Fluvisol: Subsurface analysis and soil history of the medieval city centre of Vlaardingen, the Netherlands - an integral approach

NASA Astrophysics Data System (ADS)

Kluiving, Sjoerd; De Ridder, Tim; Van Dasselaar, Marcel; Roozen, Stan; Prins, Maarten; Van Mourik, Jan

2016-04-01

In Medieval times the city of Vlaardingen (the Netherlands) was strategically located on the confluence of three rivers, the Meuse, the Merwede and the Vlaarding. A church of early 8th century was already located here. In a short period of time Vlaardingen developed into an international trading place, the most important place in the former county of Holland. Starting from the 11th century the river Meuse threatened to flood the settlement. These floods have been registered in the archives of the fluvisol and were recognised in a multidisciplinary sedimentary analysis of these archives. To secure the future of this vulnerable soil archive currently an extensive interdisciplinary research (76 mechanical drill holes, grain size analysis (GSA), thermo-gravimetric analysis (TGA), archaeological remains, soil analysis, dating methods, micromorphology, and microfauna has started in 2011 to gain knowledge on the sedimentological and pedological subsurface of the mound as well as on the well-preserved nature of the archaeological evidence. Pedogenic features are recorded with soil descriptive, micromorphological and geochemical (XRF) analysis. The soil sequence of 5 meters thickness exhibits a complex mix of 'natural' as well as 'anthropogenic layering' and initial soil formation that enables to make a distinction for relatively stable periods between periods with active sedimentation. In this paper the results of this large-scale project are demonstrated in a number of cross-sections with interrelated geological, pedological and archaeological stratification. Distinction between natural and anthropogenic layering is made on the occurrence of chemical elements phosphor and potassium. A series of four stratigraphic / sedimentary units record the period before and after the flooding disaster. Given the many archaeological remnants and features present in the lower units, we assume that the medieval landscape was drowned while it was inhabited in the 12th century AD. After a final drowning phase in the 13th century, as a reaction to it, inhabitants started to raise the surface.

Family archives as a source of information about past hydrometeorological extremes in Southern Moravia (Czech Republic)

NASA Astrophysics Data System (ADS)

Chromá, Kateřina

2014-05-01

Meteorological and hydrological extremes (hydrometeorological extremes - HMEs) cause great material damage or even loss of human lives in the present time, as well as it was in the past. For the study of their temporal and spatial variability in periods with only natural forcing factors in comparison with those combining also anthropogenic effects it is essential to have the longest possible series of HMEs. In the Czech Lands (recently the Czech Republic), systematic meteorological and hydrological observations started generally in the latter half of the 19th century. Therefore, in order to create long-term series of such extremes, it is necessary to search for other sources of information. There exist different types of documentary evidence used in historical climatology and hydrology, represented by various sources such as annals, chronicles, diaries, private letters, newspapers etc. Besides them, institutional documentary evidence (of economic and administrative character) has particular importance (e.g. taxation records). Documents in family archives represent further promising source of data related to HMEs. The documents kept by the most important lord families in Moravia (e.g. Liechtensteins, Dietrichsteins) are located in Moravian Land Archives in Brno. Besides data about family members, industrial and agricultural business, military questions, travelling and social events, they contain direct or indirect information about HMEs. It concerns descriptions of catastrophic phenomena on the particular demesne (mainly with respect to damage) as well as correspondence related to tax reductions (i.e. they can overlap with taxation records of particular estates). This contribution shows the potential of family archives as a source of information about HMEs, up to now only rarely used, which may extend our knowledge about them. Several examples of such documents are presented. The study is a part of the research project "Hydrometeorological extremes in Southern Moravia derived from documentary evidence" supported by the Grant Agency of the Czech Republic, reg. no. 13-19831S.

The Golosiiv on-line plate archive database, management and maintenance

NASA Astrophysics Data System (ADS)

Pakuliak, L.; Sergeeva, T.

2007-08-01

We intend to create online version of the database of the MAO NASU plate archive as VO-compatible structures in accordance with principles, developed by the International Virtual Observatory Alliance in order to make them available for world astronomical community. The online version of the log-book database is constructed by means of MySQL+PHP. Data management system provides a user with user interface, gives a capability of detailed traditional form-filling radial search of plates, obtaining some auxiliary sampling, the listing of each collection and permits to browse the detail descriptions of collections. The administrative tool allows database administrator the data correction, enhancement with new data sets and control of the integrity and consistence of the database as a whole. The VO-compatible database is currently constructing under the demands and in the accordance with principles of international data archives and has to be strongly generalized in order to provide a possibility of data mining by means of standard interfaces and to be the best fitted to the demands of WFPDB Group for databases of the plate catalogues. On-going enhancements of database toward the WFPDB bring the problem of the verification of data to the forefront, as it demands the high degree of data reliability. The process of data verification is practically endless and inseparable from data management owing to a diversity of data errors nature, that means to a variety of ploys of their identification and fixing. The current status of MAO NASU glass archive forces the activity in both directions simultaneously: the enhancement of log-book database with new sets of observational data as well as generalized database creation and the cross-identification between them. The VO-compatible version of the database is supplying with digitized data of plates obtained with MicroTek ScanMaker 9800 XL TMA. The scanning procedure is not total but is conducted selectively in the frames of special projects.

Experiences with making diffraction image data available: what metadata do we need to archive?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kroon-Batenburg, Loes M. J., E-mail: l.m.j.kroon-batenburg@uu.nl; Helliwell, John R.; Utrecht University, Padualaan 8, 3584 CH Utrecht

A local raw ‘diffraction data images’ archive was made available and some data sets were retrieved and reprocessed, which led to analysis of the anomalous difference densities of two partially occupied Cl atoms in cisplatin as well as a re-evaluation of the resolution cutoff in these diffraction data. General questions on storing raw data are discussed. It is also demonstrated that often one needs unambiguous prior knowledge to read the (binary) detector format and the setup of goniometer geometries. Recently, the IUCr (International Union of Crystallography) initiated the formation of a Diffraction Data Deposition Working Group with the aim ofmore » developing standards for the representation of raw diffraction data associated with the publication of structural papers. Archiving of raw data serves several goals: to improve the record of science, to verify the reproducibility and to allow detailed checks of scientific data, safeguarding against fraud and to allow reanalysis with future improved techniques. A means of studying this issue is to submit exemplar publications with associated raw data and metadata. In a recent study of the binding of cisplatin and carboplatin to histidine in lysozyme crystals under several conditions, the possible effects of the equipment and X-ray diffraction data-processing software on the occupancies and B factors of the bound Pt compounds were compared. Initially, 35.3 GB of data were transferred from Manchester to Utrecht to be processed with EVAL. A detailed description and discussion of the availability of metadata was published in a paper that was linked to a local raw data archive at Utrecht University and also mirrored at the TARDIS raw diffraction data archive in Australia. By making these raw diffraction data sets available with the article, it is possible for the diffraction community to make their own evaluation. This led to one of the authors of XDS (K. Diederichs) to re-integrate the data from crystals that supposedly solely contained bound carboplatin, resulting in the analysis of partially occupied chlorine anomalous electron densities near the Pt-binding sites and the use of several criteria to more carefully assess the diffraction resolution limit. General arguments for archiving raw data, the possibilities of doing so and the requirement of resources are discussed. The problems associated with a partially unknown experimental setup, which preferably should be available as metadata, is discussed. Current thoughts on data compression are summarized, which could be a solution especially for pixel-device data sets with fine slicing that may otherwise present an unmanageable amount of data.« less

Content-based image retrieval in medical applications for picture archiving and communication systems

NASA Astrophysics Data System (ADS)

Lehmann, Thomas M.; Guld, Mark O.; Thies, Christian; Fischer, Benedikt; Keysers, Daniel; Kohnen, Michael; Schubert, Henning; Wein, Berthold B.

2003-05-01

Picture archiving and communication systems (PACS) aim to efficiently provide the radiologists with all images in a suitable quality for diagnosis. Modern standards for digital imaging and communication in medicine (DICOM) comprise alphanumerical descriptions of study, patient, and technical parameters. Currently, this is the only information used to select relevant images within PACS. Since textual descriptions insufficiently describe the great variety of details in medical images, content-based image retrieval (CBIR) is expected to have a strong impact when integrated into PACS. However, existing CBIR approaches usually are limited to a distinct modality, organ, or diagnostic study. In this state-of-the-art report, we present first results implementing a general approach to content-based image retrieval in medical applications (IRMA) and discuss its integration into PACS environments. Usually, a PACS consists of a DICOM image server and several DICOM-compliant workstations, which are used by radiologists for reading the images and reporting the findings. Basic IRMA components are the relational database, the scheduler, and the web server, which all may be installed on the DICOM image server, and the IRMA daemons running on distributed machines, e.g., the radiologists" workstations. These workstations can also host the web-based front-ends of IRMA applications. Integrating CBIR and PACS, a special focus is put on (a) location and access transparency for data, methods, and experiments, (b) replication transparency for methods in development, (c) concurrency transparency for job processing and feature extraction, (d) system transparency at method implementation time, and (e) job distribution transparency when issuing a query. Transparent integration will have a certain impact on diagnostic quality supporting both evidence-based medicine and case-based reasoning.

Space environment data storage and access: lessons learned and recommendations for the future

NASA Astrophysics Data System (ADS)

Evans, Hugh; Heynderickx, Daniel

2012-07-01

With the ever increasing volume of space environment data available at present and planned for the near future, the demands on data storage and access methods are increasing as well. In addition, continued access to historical, archived data remains crucial. On the basis of many years of experience, the authors identify the following issues as important for continued and efficient handling of datasets now and in the future: The huge data volumes currently or very soon avaiable from a number of space missions will limi direct Internet download access to even relatively short epoch ranges of data. Therefore, data providers should establish or extend standardised data (post-) processing services so that only data query results should be downloaded. Although a single standardised data format will in all likelihood remain utopia, data providers should at least include extensive metadata with their data products, according to established standards and practices (e.g. ISTP, SPASE). Standardisation of (sets of) metadata greatly facilitates data mining and querying. The use of SQL database storage should be considered instead of, or in parallel with, classic storage of data files. The use of SQL does away with having to handle file parsing and processing, while at the same time standard access protocols can be used to (remotely) connect to such data repositories. Many data holdings are still lacking in extensive descriptions of data provenance (e.g. instrument description), content and format. Unfortunately, detailed data information is usually rejected by scientific and technical journals. Re-processing of historical archived datasets into modern formats, making them easily available and usable, is urgently required, as knowledge is being lost. A global data directory has still not been achieved; policy makers should enforce stricter rules for "broadcasting" dataset information.

Advisory Committee on human radiation experiments. Final report, Supplemental Volume 2. Sources and documentation

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

This volume and its appendixes supplement the Advisory Committee`s final report by reporting how we went about looking for information concerning human radiation experiments and intentional releases, a description of what we found and where we found it, and a finding aid for the information that we collected. This volume begins with an overview of federal records, including general descriptions of the types of records that have been useful and how the federal government handles these records. This is followed by an agency-by-agency account of the discovery process and descriptions of the records reviewed, together with instructions on how tomore » obtain further information from those agencies. There is also a description of other sources of information that have been important, including institutional records, print resources, and nonprint media and interviews. The third part contains brief accounts of ACHRE`s two major contemporary survey projects (these are described in greater detail in the final report and another supplemental volume) and other research activities. The final section describes how the ACHRE information-nation collections were managed and the records that ACHRE created in the course of its work; this constitutes a general finding aid for the materials deposited with the National Archives. The appendices provide brief references to federal records reviewed, descriptions of the accessions that comprise the ACHRE Research Document Collection, and descriptions of the documents selected for individual treatment. Also included are an account of the documentation available for ACHRE meetings, brief abstracts of the almost 4,000 experiments individually described by ACHRE staff, a full bibliography of secondary sources used, and other information.« less

Repairable-conditionally repairable damage model based on dual Poisson processes.

PubMed

Lind, B K; Persson, L M; Edgren, M R; Hedlöf, I; Brahme, A

2003-09-01

The advent of intensity-modulated radiation therapy makes it increasingly important to model the response accurately when large volumes of normal tissues are irradiated by controlled graded dose distributions aimed at maximizing tumor cure and minimizing normal tissue toxicity. The cell survival model proposed here is very useful and flexible for accurate description of the response of healthy tissues as well as tumors in classical and truly radiobiologically optimized radiation therapy. The repairable-conditionally repairable (RCR) model distinguishes between two different types of damage, namely the potentially repairable, which may also be lethal, i.e. if unrepaired or misrepaired, and the conditionally repairable, which may be repaired or may lead to apoptosis if it has not been repaired correctly. When potentially repairable damage is being repaired, for example by nonhomologous end joining, conditionally repairable damage may require in addition a high-fidelity correction by homologous repair. The induction of both types of damage is assumed to be described by Poisson statistics. The resultant cell survival expression has the unique ability to fit most experimental data well at low doses (the initial hypersensitive range), intermediate doses (on the shoulder of the survival curve), and high doses (on the quasi-exponential region of the survival curve). The complete Poisson expression can be approximated well by a simple bi-exponential cell survival expression, S(D) = e(-aD) + bDe(-cD), where the first term describes the survival of undamaged cells and the last term represents survival after complete repair of sublethal damage. The bi-exponential expression makes it easy to derive D(0), D(q), n and alpha, beta values to facilitate comparison with classical cell survival models.

The BepiColombo Spacecraft: The Mercury Transfer Module Structure Qualification Test Campaign Description

NASA Astrophysics Data System (ADS)

Martin Zurdo, M. J.

2012-07-01

The BepiColombo is a space mission to Mercury (ESA in cooperation with Japan Aerospace Exploration Agency). The spacecraft consist of three different structures: two orbiters responsible for the scientific mission (MPO and MMO) and one service module, Mercury Transfer Module (MTM), which provides propulsion and services during the journey to Mercury. Taking into account only the MTM structure, the companies involved are ASTRIUM GERMANY acting as the prime contractor and ASTRIUM UK acting as the co- prime contractor company. EADS CASA Espacio (ECE) in Spain is the company responsible for the final design, manufacturing and qualification of the MTM structure. The test campaign specimen is the MTM core structure, which corresponds to the central cone with the structure floors, shear panels and tank support structure. This test campaign qualifies the primary load path and its primary interfaces; the rest of the MTM structure is qualified by system level vibration test. In order to qualify the MTM structure, three different kinds of qualification tests have been performed: stiffness test, global strength test and local tests in different specific areas. The most relevant test during the campaign is the global strength test case, in which several external loads are introduced (different interfaces) simulating the load introduction for a selected critical flight case. There are two important items in the qualification test campaign: 1. The instrumentation of the structure, with two main functions: to control the specimen under test loads, and to demonstrate the qualification of the structure. 2. The set-up structure, designed by ECE to allow the correct load introduction on each testing case during the whole test campaign. This paper describes the MTM structure test campaign from the definition of the loads applied in each test to the qualification of the complete structure.

Fermilab Today - Related Content

Science.gov Websites

Fermilab Today Related Content Subscribe | Contact Fermilab Today | Archive | Classifieds Search Experiment Profiles Current Archive Current Fermilab Today Archive of 2015 Archive of 2014 Archive of 2013 Archive of 2012 Archive of 2011 Archive of 2010 Archive of 2009 Archive of 2008 Archive of 2007 Archive of

Gains in efficiency and scientific potential of continental climate reconstruction provided by the LRC LacCore Facility, University of Minnesota

NASA Astrophysics Data System (ADS)

Noren, A.; Brady, K.; Myrbo, A.; Ito, E.

2007-12-01

Lacustrine sediment cores comprise an integral archive for the determination of continental paleoclimate, for their potentially high temporal resolution and for their ability to resolve spatial variability in climate across vast sections of the globe. Researchers studying these archives now have a large, nationally-funded, public facility dedicated to the support of their efforts. The LRC LacCore Facility, funded by NSF and the University of Minnesota, provides free or low-cost assistance to any portion of research projects, depending on the specific needs of the project. A large collection of field equipment (site survey equipment, coring devices, boats/platforms, water sampling devices) for nearly any lacustrine setting is available for rental, and Livingstone-type corers and drive rods may be purchased. LacCore staff can accompany field expeditions to operate these devices and curate samples, or provide training prior to device rental. The Facility maintains strong connections to experienced shipping agents and customs brokers, which vastly improves transport and importation of samples. In the lab, high-end instrumentation (e.g., multisensor loggers, high-resolution digital linescan cameras) provides a baseline of fundamental analyses before any sample material is consumed. LacCore staff provide support and training in lithological description, including smear-slide, XRD, and SEM analyses. The LRC botanical macrofossil reference collection is a valuable resource for both core description and detailed macrofossil analysis. Dedicated equipment and space for various subsample analyses streamlines these endeavors; subsamples for several analyses may be submitted for preparation or analysis by Facility technicians for a fee (e.g., carbon and sulfur coulometry, grain size, pollen sample preparation and analysis, charcoal, biogenic silica, LOI, freeze drying). The National Lacustrine Core Repository now curates ~9km of sediment cores from expeditions around the world, and stores metadata and analytical data for all cores processed at the facility. Any researcher may submit sample requests for material in archived cores. Supplies for field (e.g., polycarbonate pipe, endcaps), lab (e.g., sample containers, pollen sample spike), and curation (e.g., D-tubes) are sold at cost. In collaboration with facility users, staff continually develop new equipment, supplies, and procedures as needed in order to provide the best and most comprehensive set of services to the research community.

Introducing a short version of the physical self description questionnaire: new strategies, short-form evaluative criteria, and applications of factor analyses.

PubMed

Marsh, Herbert W; Martin, Andrew J; Jackson, Susan

2010-08-01

Based on the Physical Self Description Questionnaire (PSDQ) normative archive (n = 1,607 Australian adolescents), 40 of 70 items were selected to construct a new short form (PSDQ-S). The PSDQ-S was evaluated in a new cross-validation sample of 708 Australian adolescents and four additional samples: 349 Australian elite-athlete adolescents, 986 Spanish adolescents, 395 Israeli university students, 760 Australian older adults. Across these six groups, the 11 PSDQ-S factors had consistently high reliabilities and invariant factor structures. Study 1, using a missing-by-design variation of multigroup invariance tests, showed invariance across 40 PSDQ-S items and 70 PSDQ items. Study 2 demonstrated factorial invariance over a 1-year interval (test-retest correlations .57-.90; Mdn = .77), and good convergent and discriminant validity in relation to time. Study 3 showed good and nearly identical support for convergent and discriminant validity of PSDQ and PSDQ-S responses in relation to two other physical self-concept instruments.

Climate Science Performance, Data and Productivity on Titan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mayer, Benjamin W; Worley, Patrick H; Gaddis, Abigail L

2015-01-01

Climate Science models are flagship codes for the largest of high performance computing (HPC) resources, both in visibility, with the newly launched Department of Energy (DOE) Accelerated Climate Model for Energy (ACME) effort, and in terms of significant fractions of system usage. The performance of the DOE ACME model is captured with application level timers and examined through a sizeable run archive. Performance and variability of compute, queue time and ancillary services are examined. As Climate Science advances in the use of HPC resources there has been an increase in the required human and data systems to achieve programs goals.more » A description of current workflow processes (hardware, software, human) and planned automation of the workflow, along with historical and projected data in motion and at rest data usage, are detailed. The combination of these two topics motivates a description of future systems requirements for DOE Climate Modeling efforts, focusing on the growth of data storage and network and disk bandwidth required to handle data at an acceptable rate.« less

ILRS Website Redesign

NASA Technical Reports Server (NTRS)

Noll, C.; Lee, L.; Torrence, M.

2011-01-01

The International Laser Ranging Service (ILRS) website, http://ilrs.gsfc.nasa.gov, is the central source of information for all aspects of the service. The website provides information on the organization and operation of ILRS and descriptions of ILRS components, data, and products. Furthermore, the website and provides an entry point to the archive of these data and products available through the data centers. Links are provided to extensive information on the ILRS network stations including performance assessments and data quality evaluations. Descriptions of supported satellite missions (current, future, and past) are provided to aid in station acquisition and data analysis. The current format for the ILRS website has been in use since the early years of the service. Starting in 2010, the ILRS Central Bureau began efforts to redesign the look and feel for the website. The update will allow for a review of the contents, ensuring information is current and useful. This poster will detail the proposed design including specific examples of key sections and webpages.

The Gene Expression Omnibus Database.

PubMed

Clough, Emily; Barrett, Tanya

2016-01-01

The Gene Expression Omnibus (GEO) database is an international public repository that archives and freely distributes high-throughput gene expression and other functional genomics data sets. Created in 2000 as a worldwide resource for gene expression studies, GEO has evolved with rapidly changing technologies and now accepts high-throughput data for many other data applications, including those that examine genome methylation, chromatin structure, and genome-protein interactions. GEO supports community-derived reporting standards that specify provision of several critical study elements including raw data, processed data, and descriptive metadata. The database not only provides access to data for tens of thousands of studies, but also offers various Web-based tools and strategies that enable users to locate data relevant to their specific interests, as well as to visualize and analyze the data. This chapter includes detailed descriptions of methods to query and download GEO data and use the analysis and visualization tools. The GEO homepage is at http://www.ncbi.nlm.nih.gov/geo/.

The Gene Expression Omnibus database

PubMed Central

Clough, Emily; Barrett, Tanya

2016-01-01

The Gene Expression Omnibus (GEO) database is an international public repository that archives and freely distributes high-throughput gene expression and other functional genomics data sets. Created in 2000 as a worldwide resource for gene expression studies, GEO has evolved with rapidly changing technologies and now accepts high-throughput data for many other data applications, including those that examine genome methylation, chromatin structure, and genome–protein interactions. GEO supports community-derived reporting standards that specify provision of several critical study elements including raw data, processed data, and descriptive metadata. The database not only provides access to data for tens of thousands of studies, but also offers various Web-based tools and strategies that enable users to locate data relevant to their specific interests, as well as to visualize and analyze the data. This chapter includes detailed descriptions of methods to query and download GEO data and use the analysis and visualization tools. The GEO homepage is at http://www.ncbi.nlm.nih.gov/geo/. PMID:27008011

A Prototype Publishing Registry for the Virtual Observatory

NASA Astrophysics Data System (ADS)

Williamson, R.; Plante, R.

2004-07-01

In the Virtual Observatory (VO), a registry helps users locate resources, such as data and services, in a distributed environment. A general framework for VO registries is now under development within the International Virtual Observatory Alliance (IVOA) Registry Working Group. We present a prototype of one component of this framework: the publishing registry. The publishing registry allows data providers to expose metadata descriptions of their resources to the VO environment. Searchable registries can harvest the metadata from many publishing registries and make them searchable by users. We have developed a prototype publishing registry that data providers can install at their sites to publish their resources. The descriptions are exposed using the Open Archive Initiative (OAI) Protocol for Metadata Harvesting. Automating the input of metadata into registries is critical when a provider wishes to describe many resources. We illustrate various strategies for such automation, both currently in use and planned for the future. We also describe how future versions of the registry can adapt automatically to evolving metadata schemas for describing resources.

BAPA Database: a Landslide Inventory in the Principality of Asturias (NW Spain) by Using Press Archives and Free Cartographic Servers

NASA Astrophysics Data System (ADS)

Valenzuela, P.; Domínguez-Cuesta, M. J.; Jiménez-Sánchez, M.; Mora García, M. A.

2015-12-01

Due to its geological and climatic conditions, landslides are very common and widespread phenomena in the Principality of Asturias (NW of Spain), causing economic losses and, sometimes, human victims. In this scenario, temporal prediction of instabilities becomes particularly important. Although previous knowledge indicates that rainfall is the main trigger, the lack of data hinders the proper temporal forecast of landslides in the region. To resolve this deficiency, a new landslide inventory is being developed: the BAPA (Base de datos de Argayos del Principado de Asturias-Principality of Asturias Landslide Database). Data collection is mainly performed through the gathering of local newspaper archives, with special emphasis on the registration of spatial and temporal information. Moreover, a BAPA App and a BAPA website (http://geol.uniovi.es/BAPA) have been developed to easily obtain additional information from authorities and private individuals. Presently, dataset covers the period 1980-2015, registering more than 2000 individual landslide events. Fifty-two per cent of the records provide accurate dates, showing the usefulness of press archives as temporal records. The use of free cartographic servers, such as Google Maps, Google Street View and Iberpix (Government of Spain), combined with the spatial descriptions and photographs contained in the press releases, makes it possible to determine the exact location in fifty-eight per cent of the records. Field work performed to date has allowed the validation of the methodology proposed to obtain spatial data. In addition, BAPA database contain information about: source, typology of landslides, triggers, damages and costs.

Installation Restoration Program. Phase 1. Records Search, Hazardous Materials Disposal Sites, Eglin AFB, Florida

DTIC Science & Technology

1981-10-01

Okaloosa Co. 3-12 Crestview South Quadrangle, Florida-Okaloosa Co. -13 Mossy ead Quadrangle, Florida-Walton Co 3-14 E-1 EGUN AFB 4,h aa V, WRAMATIO...I) Um AYPM hIN1DS SP * So". AM T 0 Tou A is a O I. h E-2 ES ENGINEERING -SCIENCE V%777-7NN7 .7-7 EGUN AFB 0.4 .m ... (1) WMg LAN DOSAMU *Y* CO u...r Oumm *p S(S Ann~ Il~~O 0*aAMa 2-3 ES ENGINEER ING - SCIENCE EGUN AFB %Tt MAR ESTHER * : . . - . - ~ - ~ r W R G H T L A N D F I L L 3 SITE 0296

JWST Full-Scale Model on Display in Germany

NASA Image and Video Library

2010-03-10

JWST Full-Scale Model on Display. A full-scale model of the James Webb Space Telescope was built by the prime contractor, Northrop Grumman, to provide a better understanding of the size, scale and complexity of this satellite. The model is constructed mainly of aluminum and steel, weighs 12,000 lb., and is approximately 80 feet long, 40 feet wide and 40 feet tall. The model requires 2 trucks to ship it and assembly takes a crew of 12 approximately four days. This model has travelled to a few sites since 2005. The photographs below were taken at some of its destinations. The model is pictured here in Munich, Germany Credit: EADS Astrium

JWST Full-Scale Model on Display in Germany

NASA Image and Video Library

2017-12-08

JWST Full-Scale Model on Display. A full-scale model of the James Webb Space Telescope was built by the prime contractor, Northrop Grumman, to provide a better understanding of the size, scale and complexity of this satellite. The model is constructed mainly of aluminum and steel, weighs 12,000 lb., and is approximately 80 feet long, 40 feet wide and 40 feet tall. The model requires 2 trucks to ship it and assembly takes a crew of 12 approximately four days. This model has travelled to a few sites since 2005. The photographs below were taken at some of its destinations. The model is pictured here in Munich, Germany Credit: EADS Astrium

Further Studies of Thunderstorm Conditions Affecting Flight Operations: Turbulence

DTIC Science & Technology

1949-03-01

3^——- flft).^--.’""-. *I-ÄB&H*- i:S*£9: II HiEAD-Q^ AfFf ERS J" , AI;R WEA| HER: SEsmoM •HEADQUARTERS;— AIR T/SATHER SERVICE ’ Andrews...Sams gsagagj IlliilJss akSfepftirg -r-jf*’^«sSPa^=^?L^? «-^^as^«^äs*^^i^s8ä«^ fc -i^^-rr*^i^s^^^^g^^S^^S^^Sa?^^^^^g^^^^^^^a -33- . f 2£SggÖ...measured at various duriag Ohio operations, 194 ?’. " Draft Yalue JISE^S- Flight Altitude (thousands of fest) 5 48« J£BS) I gJ " 1 U I 29-JJ

AUTOCASK (AUTOmatic Generation of 3-D CASK models). A microcomputer based system for shipping cask design review analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gerhard, M.A.; Sommer, S.C.

1995-04-01

AUTOCASK (AUTOmatic Generation of 3-D CASK models) is a microcomputer-based system of computer programs and databases developed at the Lawrence Livermore National Laboratory (LLNL) for the structural analysis of shipping casks for radioactive material. Model specification is performed on the microcomputer, and the analyses are performed on an engineering workstation or mainframe computer. AUTOCASK is based on 80386/80486 compatible microcomputers. The system is composed of a series of menus, input programs, display programs, a mesh generation program, and archive programs. All data is entered through fill-in-the-blank input screens that contain descriptive data requests.

Observations of Comets and Eclipses in the Andes

NASA Astrophysics Data System (ADS)

Ziółkowski, Mariusz

There is no doubt that the Incas possessed a system for observing and interpreting unusual astronomical phenomena, such as eclipses or comets. References to it, however, are scarce, often of anecdotal nature and are not collected into any coherent "Inca observation catalog". The best documented of such events is the "Ataw Wallpa's comet", seen in Cajamarca in July of 1533 and the solar eclipse, that in 1543, prevented conquistador Lucas Martínez from discovering the rich silver mines in northern Chile. Archived descriptions of the Andean population's reaction to these phenomena indicate that they were treated as extremely important omens, that should not, under any circumstances, be ignored.

An overview of the catalog manager

NASA Technical Reports Server (NTRS)

Irani, Frederick M.

1986-01-01

The Catalog Manager (CM) is being used at the Goddard Space Flight Center in conjunction with the Land Analysis System (LAS) running under the Transportable Applications Executive (TAE). CM maintains a catalog of file names for all users of the LAS system. The catalog provides a cross-reference between TAE user file names and fully qualified host-file names. It also maintains information about the content and status of each file. A brief history of CM development is given and a description of naming conventions, catalog structure and file attributes, and archive/retrieve capabilities is presented. General user operation and the LAS user scenario are also discussed.

The ERESE Project: Interfacing with the ERDA Digital Archive and ERR Reference Database in EarthRef.org

NASA Astrophysics Data System (ADS)

Koppers, A. A.; Staudigel, H.; Mills, H.; Keller, M.; Wallace, A.; Bachman, N.; Helly, J.; Helly, M.; Miller, S. P.; Massell Symons, C.

2004-12-01

To bridge the gap between Earth science teachers, librarians, scientists and data archive managers, we have started the ERESE project that will create, archive and make available "Enduring Resources in Earth Science Education" through information technology (IT) portals. In the first phase of this National Science Digital Library (NSDL) project, we are focusing on the development of these ERESE resources for middle and high school teachers to be used in lesson plans with "plate tectonics" and "magnetics" as their main theme. In this presentation, we will show how these new ERESE resources are being generated, how they can be uploaded via online web wizards, how they are archived, how we make them available via the EarthRef.org Digital Archive (ERDA) and Reference Database (ERR), and how they relate to the SIOExplorer database containing data objects for all seagoing cruises carried out by the Scripps Institution of Oceanography. The EarthRef.org web resource uses the vision of a "general description" of the Earth as a geological system to provide an IT infrastructure for the Earth sciences. This emphasizes the marriage of the "scientific process" (and its results) with an educational cyber-infrastructure for teaching Earth sciences, on any level, from middle school to college and graduate levels. Eight different databases reside under EarthRef.org from which ERDA holds any digital object that has been uploaded by other scientists, teachers and students for free, while the ERR holds more than 80,000 publications. For more than 1,500 of these publications, this latter database makes available for downloading JPG/PDF images of the abstracts, data tables, methods and appendices, together with their digitized contents in Microsoft Word and Excel format. Both holdings are being used to store the ERESE objects that are being generated by a group of undergraduate students majoring in Environmental Systems (ESYS) program at the UCSD with an emphasis on the Earth Sciences. These students perform library and internet research in order to design and generate these "Enduring Resources in Earth Science Education" that they test by closely interacting with the research faculty at the Scripps Institution of Oceanography. Typical ERESE resources can be diagrams, model cartoons, maps, data sets for analyses, and glossary items and essays to explain certain Earth Science concepts and are ready to be used in the classroom.

Data Management and Archiving - a Long Process

NASA Astrophysics Data System (ADS)

Gebauer, Petra; Bertelmann, Roland; Hasler, Tim; Kirchner, Ingo; Klump, Jens; Mettig, Nora; Peters-Kottig, Wolfgang; Rusch, Beate; Ulbricht, Damian

2014-05-01

Implementing policies for research data management to the end of data archiving at university institutions takes a long time. Even though, especially in geosciences, most of the scientists are familiar to analyze different sorts of data, to present statistical results and to write publications sometimes based on big data records, only some of them manage their data in a standardized manner. Much more often they have learned how to measure and to generate large volumes of data than to document these measurements and to preserve them for the future. Changing staff and limited funding make this work more difficult, but it is essential in a progressively developing digital and networked world. Results from the project EWIG (Translates to: Developing workflow components for long-term archiving of research data in geosciences), funded by Deutsche Forschungsgemeinschaft, will help on these theme. Together with the project partners Deutsches GeoForschungsZentrum Potsdam and Konrad-Zuse-Zentrum für Informationstechnik Berlin a workflow to transfer continuously recorded data from a meteorological city monitoring network into a long-term archive was developed. This workflow includes quality assurance of the data as well as description of metadata and using tools to prepare data packages for long term archiving. It will be an exemplary model for other institutions working with similar data. The development of this workflow is closely intertwined with the educational curriculum at the Institut für Meteorologie. Designing modules to run quality checks for meteorological time series of data measured every minute and preparing metadata are tasks in actual bachelor theses. Students will also test the usability of the generated working environment. Based on these experiences a practical guideline for integrating research data management in curricula will be one of the results of this project, for postgraduates as well as for younger students. Especially at the beginning of the scientific career it is necessary to become familiar with all issues concerning data management. The outcomes of EWIG are intended to be generic enough to be easily adopted by other institutions. University lectures in meteorology were started to teach future scientific generations right from the start how to deal with all sorts of different data in a transparent way. The progress of the project EWIG can be followed on the web via ewig.gfz-potsdam.de

Nimbus-7 Total Ozone Mapping Spectrometer (TOMS) Data Products User's Guide

NASA Technical Reports Server (NTRS)

McPeters, Richard D.; Bhartia, P. K.; Krueger, Arlin J.; Herman, Jay R.; Schlesinger, Barry M.; Wellemeyer, Charles G.; Seftor, Colin J.; Jaross, Glen; Taylor, Steven L.; Swissler, Tom;

New York Chapter History of Military Medicine Award. U.S. Army medical helicopters in the Korean War.

PubMed

Driscoll, R S

2001-04-01

Medical evacuation helicopters are taken for granted in today's military. However, the first use of helicopters for this purpose in the Korean War was not done intentionally but as a result of the necessity of moving patients rapidly over difficult Korean terrain and of the early ebbing of the main battle line. The objective of this essay is to increase the historical awareness of military medical evacuation helicopters in the Korean War during this 50th anniversary year. By describing the many challenges and experiences encountered in implementing the use of helicopters for evacuation, the reader will appreciate how a technology developed for another use helped in the success of evacuating nearly 22,000 patients while contributing to establishing a mortality rate of wounded of 2.4%. The preparation to write this essay included archival research of historical reports, records, and oral histories from the archives of the U.S. Army Center for Military History. Additionally, a search of journal articles written during and after the Korean War was conducted. The result is a comprehensive description of the use of medical evacuation helicopters in the Korean War.

A spatio-temporal landslide inventory for the NW of Spain: BAPA database

NASA Astrophysics Data System (ADS)

Valenzuela, Pablo; Domínguez-Cuesta, María José; Mora García, Manuel Antonio; Jiménez-Sánchez, Montserrat

2017-09-01

A landslide database has been created for the Principality of Asturias, NW Spain: the BAPA (Base de datos de Argayos del Principado de Asturias - Principality of Asturias Landslide Database). Data collection is mainly performed through searching local newspaper archives. Moreover, a BAPA App and a BAPA website (http://geol.uniovi.es/BAPA) have been developed to obtain additional information from citizens and institutions. Presently, the dataset covers the period 1980-2015, recording 2063 individual landslides. The use of free cartographic servers, such as Google Maps, Google Street View and Iberpix (Government of Spain), combined with the spatial descriptions and pictures contained in the press news, makes it possible to assess different levels of spatial accuracy. In the database, 59% of the records show an exact spatial location, and 51% of the records provided accurate dates, showing the usefulness of press archives as temporal records. Thus, 32% of the landslides show the highest spatial and temporal accuracy levels. The database also gathers information about the type and characteristics of the landslides, the triggering factors and the damage and costs caused. Field work was conducted to validate the methodology used in assessing the spatial location, temporal occurrence and characteristics of the landslides.

Reproducible computational biology experiments with SED-ML - The Simulation Experiment Description Markup Language

PubMed Central

2011-01-01

Background The increasing use of computational simulation experiments to inform modern biological research creates new challenges to annotate, archive, share and reproduce such experiments. The recently published Minimum Information About a Simulation Experiment (MIASE) proposes a minimal set of information that should be provided to allow the reproduction of simulation experiments among users and software tools. Results In this article, we present the Simulation Experiment Description Markup Language (SED-ML). SED-ML encodes in a computer-readable exchange format the information required by MIASE to enable reproduction of simulation experiments. It has been developed as a community project and it is defined in a detailed technical specification and additionally provides an XML schema. The version of SED-ML described in this publication is Level 1 Version 1. It covers the description of the most frequent type of simulation experiments in the area, namely time course simulations. SED-ML documents specify which models to use in an experiment, modifications to apply on the models before using them, which simulation procedures to run on each model, what analysis results to output, and how the results should be presented. These descriptions are independent of the underlying model implementation. SED-ML is a software-independent format for encoding the description of simulation experiments; it is not specific to particular simulation tools. Here, we demonstrate that with the growing software support for SED-ML we can effectively exchange executable simulation descriptions. Conclusions With SED-ML, software can exchange simulation experiment descriptions, enabling the validation and reuse of simulation experiments in different tools. Authors of papers reporting simulation experiments can make their simulation protocols available for other scientists to reproduce the results. Because SED-ML is agnostic about exact modeling language(s) used, experiments covering models from different fields of research can be accurately described and combined. PMID:22172142

Fermilab History and Archives Project | Norman F. Ramsey

Science.gov Websites

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