75 FR 51479 - Notice of Availability of the Final Environmental Impact Statement for the Chevron Energy...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-20

... (EIS) for the Chevron Energy Solutions/Solar Millennium (CESSM), LLC's Blythe Solar Power Plant (BSPP... project and amend the CDCA Plan to prohibit solar energy projects on the project site. The BLM will take..., LVRWB09B2600] Notice of Availability of the Final Environmental Impact Statement for the Chevron Energy...

75 FR 17762 - Notice of Availability of the Draft Environmental Impact Statement/Staff Assessment for the Solar...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-07

... related to the RSPP by any of the following methods: Web site: http://www.energy.ca.gov/sitingcases/solar..., California Energy Commission, 1516 Ninth Street, MS-15, Sacramento, California 95814. Copies of the Solar... available or unavailable to solar energy projects. The CDCA Plan (1980, as amended), while recognizing the...

CDCA7L and Mechanisms of Increased Male Bias in Glioma

DTIC Science & Technology

2016-05-01

interested in whether NF1 mutations affect the molecular function of CDCA7L and whether sex -specific treatments may be more effective for treating these...astrocyte phenotypes, and catecholamine levels. 2. Keywords Neurofibromatosis type 1 CDCA7L astrocytoma glioblastoma MAO catecholamines sex ...2015 NF Research Symposium as described under (6) Products. We are revising a manuscript based on his findings so far on the sex -specific activity

Synthesis and electromagnetic interference shielding of cellulose-derived carbon aerogels functionalized with α-Fe2O3 and polypyrrole.

PubMed

Wan, Caichao; Li, Jian

2017-04-01

Eco-friendly cellulose-derived carbon aerogels (CDCA) were employed as porous substrate to integrate with α-Fe 2 O 3 and polypyrrole (PPy) via pyrolysis and vapor-phase polymerization. The SEM and TEM observations present that the wrinkled PPy sheets and the α-Fe 2 O 3 nanoparticles were well dispersed in CDCA. The strong interactions (such as hydrogen bonding) between the substrate and the nanomaterials were demonstrated by the FTIR and XPS analysis. When utilized as electromagnetic interference (EMI) shielding materials, the α-Fe 2 O 3 /PPy/CDCA (FPCA) composite has the highest total shielding effectiveness (SE total ) of 39.4dB, about 2.0, 2.9, and 1.3 times that of the acid-treated CDCA (19.3dB), PPy (13.6dB), and α-Fe 2 O 3 /CDCA (29.3dB), respectively. Moreover, the shielding effectiveness due to absorption accounts for 78.2%-84.2% of SE total for FPCA, indicative of the absorption-dominant shielding mechanism contributing to alleviating secondary radiation. These features make the composite a useful alternative candidate for EMI shielding. Copyright © 2017 Elsevier Ltd. All rights reserved.

The Child Dental Control Assessment (CDCA) in youth: reliability, validity and cross-cultural differences.

PubMed

Coolidge, T; Heima, M; Heaton, L J; Nakai, Y; Höskuldsson, O; Smith, T A; Weinstein, P; Milgrom, P

2005-03-01

The Child Dental Control Assessment (CDCA) measures children's preferred control strategies in the dental situation. Three studies are reported, assessing aspects of this instrument in youths from the USA, Japan and Australia. In particular, measurements were made as to the reliability and validity of this instrument in this age group in the three cultures, as well as comparing some results across cultures. These studies used a questionnaire design. Questionnaires (including the CDCA and other measures) were given to youths aged 11-15 in the three cultures. In one culture, youths received the questionnaire twice, to compute test-retest reliability. The measure's reliability and validity were similar to those of other measures. The CDCA behaves similarly to the Revised Iowa Dental Control Index (R-IDCI). Youths in all three cultures showed similar responses, although the Japanese were less likely to endorse items. Internal reliability of the scale ranged from 0.74 to 0.85. Test- retest reliability was 0.74. Participants in the High Desire/Low Predicted classification on the R-IDCI scored higher on the CDCA (t (73) = 2.9, p < .01). In the Japanese and Australian samples the correlation between CDCA and dental fear was 0.29-0.33 (p < .001). The Australian and USA samples scored significantly higher than the Japanese sample (overall F(2,1544) = 383.98, p < .001, followed by Tukey's HSD, p < .001). These results provide evidence for the reliability and validity of the CDCA in youth. It appears to measure the discrepancy between Desired and Predicted Control identified in the Revised Iowa Dental Control Index (R-IDCI). Responses of the youth in all three cultures were similar, indicating common dental control preferences for individuals of this age. However, consistent with cultural values, Japanese youth were less likely to endorse the control strategies. These results underline the need to develop culturally-specific, as well as situationally-specific control measures.

Resource inventory techniques used in the California Desert Conservation Area

NASA Technical Reports Server (NTRS)

Mcleod, R. G.; Johnson, H. B.

1981-01-01

A variety of conventional and remotely sensed data for the 25 million acre California Desert Conservation Area (CDCA) have been integrated and analyzed to estimate range carrying capacity. Multispectral classification was performed on a digital mosaic of ten Landsat frames. Multispectral classes were correlated with low level aerial photography, quantified and aggregated by grazing allotment, land ownership, and slope.

Protoscolicidal effects of chenodeoxycholic acid on protoscoleces of Echinococcus granulosus.

PubMed

Shi, Hongjuan; Lei, Ying; Wang, Bo; Wang, Zhuo; Xing, Guoqiang; Lv, Hailong; Jiang, Yufeng

2016-08-01

Dissemination of protoscoleces-rich fluid during surgical operation for cystic echinococcosis is a major cause of its recurrence. Instillation of a scolicidal agent into hydatid cysts to reduce the risk of spillage of viable protoscoleces is an integral part of the surgical technique employed by many surgeons. In this study, the protoscolicidal effect of chenodeoxycholic acid (CDCA) was investigated. Freshly isolated protoscoleces were subjected to CDCA treatment (500, 1000, 2000, and 3000 μmol/L), and the effects on protoscoleces were investigated with the help of 0.1% eosin staining, electron microscopy, and colorimetric assay of caspase-3 like activity. Dose-dependent mortality of Echinococcus granulosus protoscoleces was observed within a few days of CDCA treatment. The treated protoscoleces showed loss of viability, and morphological changes such as contraction of the soma region, formation of blebs, rostellar disorganization, loss of hooks, destruction of microtriches, and formation of vesicles, lipid droplets, and lamellar bodies. Apoptosis was evident in the treated protoscoleces, as compared to the control group, which were cultivated for nearly 3 months. Our study indicates a therapeutic potential for CDCA as a protoscolicidal agent against E. granulosus. However, further studies are needed to test the long-term effects of CDCA in animal models. Copyright © 2016 Elsevier Inc. All rights reserved.

Metabolism of lithocholic and chenodeoxycholic acids in the squirrel monkey

DOE Office of Scientific and Technical Information (OSTI.GOV)

Suzuki, H.; Hamada, M.; Kato, F.

1985-09-01

Metabolism of lithocholic acid (LCA) and chenodeoxycholic acid (CDCA) was studied in the squirrel monkey to clarify the mechanism of the lack of toxicity of CDCA in this animal. Radioactive LCA was administered to squirrel monkeys with biliary fistula. Most radioactivity was excreted in the bile in the form of unsulfated lithocholyltaurine. The squirrel monkey thus differs from humans and chimpanzees, which efficiently sulfate LCA, and is similar to the rhesus monkey and baboon in that LCA is poorly sulfated. When labeled CDCA was orally administered to squirrel monkeys, less than 20% of the dosed radioactivity was recovered as LCAmore » and its further metabolites in feces over 3 days, indicating that bacterial metabolism of CDCA into LCA is strikingly less than in other animals and in humans. It therefore appears that LCA, known as a hepatotoxic secondary bile acid, is not accumulated in the squirrel monkey, not because of its rapid turnover through sulfation, but because of the low order of its production.« less

Nucleation time of gall bladder bile in gall stone patients: influence of bile acid treatment.

PubMed Central

Sahlin, S; Ahlberg, J; Angelin, B; Reihnér, E; Einarsson, K

1991-01-01

The time required for precipitation of cholesterol crystals (nucleation time, NT) was determined and related to the cholesterol saturation in gall bladder bile of gall stone free subjects (n = 11), patients with pigment stones (n = 3), and patients with cholesterol gall stones (n = 30) undergoing cholecystectomy. Seven of the gall stone patients had been treated with chenodeoxycholic acid (CDCA) and nine with ursodeoxycholic acid (UDCA), 15 mg/kg/day for three weeks before operation. NT was longer in gall stone free subjects (mean, 20 days), patients with pigment stones (14 days) and patients treated with CDCA (24 days) and UDCA (17 days) compared with untreated patients with cholesterol gall stones (1.5 days). In spite of low cholesterol saturation and prolonged NT, and in contrast to those treated with CDCA, four of the nine patients treated with UDCA had cholesterol crystals in their bile. These observations give further support to the concept that the mechanism for inducing gall stone dissolution may be different for CDCA and UDCA. PMID:1773966

Coral Cd/Ca and Mn/Ca records of ENSO variability in the Gulf of California

NASA Astrophysics Data System (ADS)

Carriquiry, J. D.; Villaescusa, J. A.

2010-06-01

We analyzed the trace element ratios Cd/Ca and Mn/Ca in three coral colonies (Porites panamensis (1967-1989), Pavona clivosa (1967-1989) and Pavona gigantea (1979-1989)) from Cabo Pulmo reef, Southern Gulf of California, Mexico, to assess the oceanographic changes caused by El Niño - Southern Oscillation (ENSO) events in the Eastern Tropical North Pacific (ETNP). Interannual variations in the coral Cd/Ca and Mn/Ca ratios showed clear evidence that incorporation of Cd and Mn in the coral skeleton was influenced by ENSO conditions, but the response for each metal was controlled by different processes. The Mn/Ca ratios were significantly higher during ENSO years (p<0.05) relative to non-ENSO years for the three species of coral. In contrast, the Cd/Ca was systematically lower during ENSO years, but the difference was significant (p<0.05) only in Pavona gigantea. A decrease in the incorporation of Cd and a marked increase in Mn indicated strongly reduced vertical mixing in the Gulf of California during the mature phase of El Niño. The oceanic warming during El Niño events produces a relaxation of upwelling and a stabilization of the thermocline, which may act as a physical barrier limiting the transport of Cd from deeper waters into the surface layer. In turn, this oceanic condition can increase the residence time of particulate-Mn in surface waters, allowing an increase in the photo-reduction of particulate-Mn and the release of available Mn into the dissolved phase. These results support the use of Mn/Ca and Cd/Ca ratios in biogenic carbonates as tracers of increases in ocean stratification and trade wind weakening and/or collapse in the ETNP during ENSO episodes.

Coral Cd/Ca and Mn/Ca records of El Niño variability in the Gulf of California

NASA Astrophysics Data System (ADS)

Carriquiry, J. D.; Villaescusa, J. A.

2010-02-01

We analyzed the trace element ratios Cd/Ca and Mn/Ca in three coral colonies (Pavona gigantea, Pavona clivosa and Porites panamensis) from Cabo Pulmo reef, Southern Gulf of California, Mexico, to assess the oceanographic changes caused by El Niño - Southern Oscillation (ENSO) events in the Eastern Tropical North Pacific (ETNP). The interannual variations in the coral Cd/Ca and Mn/Ca ratios show clear evidence that incorporation of Cd and Mn in the coral skeleton are influenced by ENSO conditions, but the response for each metal is controlled by different process. The Mn/Ca ratios were significantly higher during ENSO years (p<0.05) relative to non-ENSO years for the three species of coral. In contrast, the Cd/Ca was systematically lower during ENSO years, but it was significant (p<0.05) only in P. gigantea. The decrease in the incorporation of Cd, and the marked increase in Mn during the mature phase of El Niño indicate strongly reduced vertical mixing in the Gulf of California. The oceanic warming during El Niño events produces a relaxation of upwelling and a stabilization of the thermocline which acts as a physical barrier limiting the transport of Cd from deeper waters into the surface layer. In turn, this oceanic condition can increase the residence time of particulate-Mn in surface waters, which in turn increases the photo-reduction of particulate-Mn and the release of the available Mn into the dissolved phase. These results provide validation for using Mn/Ca and Cd/Ca in biogenic carbonates as tracers of changes in ocean stratification and trade wind weakening and/or collapse in the ETNP during ENSO episodes.

Efficacy of Magnesium Trihydrate of Ursodeoxycholic Acid and Chenodeoxycholic Acid for Gallstone Dissolution: A Prospective Multicenter Trial.

PubMed

Hyun, Jong Jin; Lee, Hong Sik; Kim, Chang Duck; Dong, Seok Ho; Lee, Seung-Ok; Ryu, Ji Kon; Lee, Don Haeng; Jeong, Seok; Kim, Tae Nyeun; Lee, Jin; Koh, Dong Hee; Park, Eun Taek; Lee, In-Seok; Yoo, Byung Moo; Kim, Jin Hong

2015-07-01

Cholecystectomy is necessary for the treatment of symptomatic or complicated gallbladder (GB) stones, but oral litholysis with bile acids is an attractive alternative therapeutic option for asymptomatic or mildly symptomatic patients. This study was conducted to evaluate the efficacy of magnesium trihydrate of ursodeoxycholic acid (UDCA) and chenodeoxycholic acid (CDCA) on gallstone dissolution and to investigate improvements in gallstone-related symptoms. A prospective, multicenter, phase 4 clinical study to determine the efficacy of orally administered magnesium trihydrate of UDCA and CDCA was performed from January 2011 to June 2013. The inclusion criteria were GB stone diameter ≤15 mm, GB ejection fraction ≥50%, radiolucency on plain X-ray, and asymptomatic/mildly symptomatic patients. The patients were prescribed one capsule of magnesium trihydrate of UDCA and CDCA at breakfast and two capsules at bedtime for 6 months. The dissolution rate, response rate, and change in symptom score were evaluated. A total of 237 subjects were enrolled, and 195 subjects completed the treatment. The dissolution rate was 45.1% and the response rate was 47.2% (92/195) after 6 months of administration of magnesium trihydrate of UDCA and CDCA. Only the stone diameter was significantly associated with the response rate. Both the symptom score and the number of patients with symptoms significantly decreased regardless of stone dissolution. Adverse events necessitating discontinuation of the drug, surgery, or endoscopic management occurred in 2.5% (6/237) of patients. Magnesium trihydrate of UDCA and CDCA is a well-tolerated bile acid that showed similar efficacy for gallstone dissolution and improvement of gallstone-related symptoms as that shown in previous studies.

Liver Dysfunction and Phosphatidylinositol-3-Kinase Signalling in Early Sepsis: Experimental Studies in Rodent Models of Peritonitis

PubMed Central

Westermann, Martin; Lambeck, Sandro; Lupp, Amelie; Rudiger, Alain; Dyson, Alex; Carré, Jane E.; Kortgen, Andreas; Krafft, Christoph; Popp, Jürgen; Sponholz, Christoph; Fuhrmann, Valentin; Hilger, Ingrid; Claus, Ralf A.; Riedemann, Niels C.; Wetzker, Reinhard; Singer, Mervyn; Trauner, Michael; Bauer, Michael

2012-01-01

Background Hepatic dysfunction and jaundice are traditionally viewed as late features of sepsis and portend poor outcomes. We hypothesized that changes in liver function occur early in the onset of sepsis, yet pass undetected by standard laboratory tests. Methods and Findings In a long-term rat model of faecal peritonitis, biotransformation and hepatobiliary transport were impaired, depending on subsequent disease severity, as early as 6 h after peritoneal contamination. Phosphatidylinositol-3-kinase (PI3K) signalling was simultaneously induced at this time point. At 15 h there was hepatocellular accumulation of bilirubin, bile acids, and xenobiotics, with disturbed bile acid conjugation and drug metabolism. Cholestasis was preceded by disruption of the bile acid and organic anion transport machinery at the canalicular pole. Inhibitors of PI3K partially prevented cytokine-induced loss of villi in cultured HepG2 cells. Notably, mice lacking the PI3Kγ gene were protected against cholestasis and impaired bile acid conjugation. This was partially confirmed by an increase in plasma bile acids (e.g., chenodeoxycholic acid [CDCA] and taurodeoxycholic acid [TDCA]) observed in 48 patients on the day severe sepsis was diagnosed; unlike bilirubin (area under the receiver-operating curve: 0.59), these bile acids predicted 28-d mortality with high sensitivity and specificity (area under the receiver-operating curve: CDCA: 0.77; TDCA: 0.72; CDCA+TDCA: 0.87). Conclusions Liver dysfunction is an early and commonplace event in the rat model of sepsis studied here; PI3K signalling seems to play a crucial role. All aspects of hepatic biotransformation are affected, with severity relating to subsequent prognosis. Detected changes significantly precede conventional markers and are reflected by early alterations in plasma bile acids. These observations carry important implications for the diagnosis of liver dysfunction and pharmacotherapy in the critically ill. Further clinical work is necessary to extend these concepts into clinical practice. Please see later in the article for the Editors' Summary PMID:23152722

Sensitivity and Specificity of Biochemical Tests for Diagnosis of Intrahepatic Cholestasis of Pregnancy.

PubMed

Jurate, Kondrackiene; Rimantas, Zalinkevicius; Jolanta, Sumskiene; Vladas, Gintautas; Limas, Kupcinskas

2017-01-01

Intrahepatic cholestasis of pregnancy (ICP) is linked with increased risk of fetal complications. An accurate diagnostic test is needed to diagnose this disorder on time. We aimed to assess sensitivity and specificity of laboratory tests used for diagnosis of intrahepatic cholestasis of pregnancy and determine more reliable cut-off values of transaminases. Sixty one symptomatic patients with ICP and 29 healthy pregnant women were included in the retrospective analysis. ICP patients had higher total bile acids (TBA) levels than healthy women (32 vs. 6; P < 0.0001) due to increase in cholic acid (CA) and chenodeoxycholic acid (CDCA). CA/CDCA ratio was significantly higher in ICP patients compared to healthy pregnant women (1.13 vs. 0.68; P < 0.00002). TBA, CA, CDCA and CA/CDCA ratio demonstrate the following sensitivity (94%, 96%, 89%, 71.9%) and specificity (63%, 63%, 59%, 79.3%, respectively) for ICP diagnosis. Lowering cut-off values for ALT (31 U/L) and AST (30 U/L) resulted only in minimal increase of sensitivity to 92.2% vs. 90.1% for ALT and to 92.2%, vs. 90.6% for AST. The present study did not reveal any single specific and sensitive marker for reliable diagnosis of ICP. Establishment of lower cut-off values for transaminases activity might only minimally increase the accuracy of diagnosing ICP.

Mesomorphic properties of multi-arm chenodeoxycholic acid-derived liquid crystals

NASA Astrophysics Data System (ADS)

Dong, Liang; Yao, Miao; Wu, Shuang-jie; Yao, Dan-Shu; Hu, Jian-She; He, Xiao-zhi; Tian, Mei

2017-12-01

Four multi-arm liquid crystals (LCs) based on chenodeoxycholic acid, termed as 2G-PD, 2G-IB, 2G-BD and 5G-GC, respectively, have been synthesised by convergent method, which nematic LC, 6-(4-((4-ethoxybenzoyl)oxy)phenoxy)-6-oxohexanoic acid, was used as side arm, and chenodeoxycholic acid (CDCA) was used as the first core, 1,2-propanediol (PD), isosorbide (IB), 4,4‧-biphenyldiol (BD) and glucose (GC) were used as the second core, respectively. The first generation product, CDCA2EA, displayed cholesteric phase. The second generation products 2G-BD and 5G-GC displayed cholesteric phase, while 2G-PD and 2G-IB exhibited nematic phase. The multi-arm LC, 2G-IB, did not display cholesteric phase although the two cores were all chiral ones. The result indicated that chirality of the second core sometimes made the multi-arm LCs display nematic phase when cholesteric CDCA-derivative were introduced into the second core. Some attention should be paid on molecular conformation besides the introduction of chiral cores for multi-chiral-core LCs to obtain cholesteric phase.

Mineral resource potential map of the Bighorn Mountains Wilderness Study Area (CDCA-217), San Bernardino County, California

USGS Publications Warehouse

Matti, Jonathan C.; Cox, Brett F.; Rodriguez, Eduardo A.; Obi, Curtis M.; Powell, Robert E.; Hinkle, Margaret E.; Griscom, Andrew; Sabine, Charles; Cwick, Gary J.

1982-01-01

Geological, geochemical, and geophysical evidence, together with a review of historical mining and prospecting activities, suggests that most of the Bighorn Mountains Wilderness Study Area has low potential for the discovery of all types of mineral and energy resources-including precious and base metals, building stone and aggregate, fossil fuels, radioactive-mineral resources, and geothermal resources. Low-grade mineralization has been documented in one small area near Rattlesnake Canyon, and this area has low to moderate potential for future small-scale exploration and development of precious and base metals. Thorium and uranium enrichment have been documented in two small areas in the eastern part of the wilderness study area; these two areas have low to moderate potential for future small-scale exploration and development of radioactive-mineral resources.

OY-TES-1 may regulate the malignant behavior of liver cancer via NANOG, CD9, CCND2 and CDCA3: a bioinformatic analysis combine with RNAi and oligonucleotide microarray.

PubMed

Hu, Qiping; Fu, Jun; Luo, Bin; Huang, Miao; Guo, Wenwen; Lin, Yongda; Xie, Xiaoxun; Xiao, Shaowen

2015-04-01

Given its tumor-specific expression, including liver cancer, OY-TES-1 is a potential molecular marker for the diagnosis and immunotherapy of liver cancers. However, investigations of the mechanisms and the role of OY-TES-1 in liver cancer are rare. In the present study, based on a comprehensive bioinformatic analysis combined with RNA interference (RNAi) and oligonucleotide microarray, we report for the first time that downregulation of OY-TES-1 resulted in significant changes in expression of NANOG, CD9, CCND2 and CDCA3 in the liver cancer cell line BEL-7404. NANOG, CD9, CCND2 and CDCA3 may be involved in cell proliferation, migration, invasion and apoptosis, yet also may be functionally related to each other and OY-TES-1. Among these molecules, we identified that NANOG, containing a Kazal-2 binding motif and homeobox, may be the most likely candidate protein interacting with OY-TES-1 in liver cancer. Thus, the present study may provide important information for further investigation of the roles of OY-TES-1 in liver cancer.

Activation of farnesoid X receptor promotes triglycerides lowering by suppressing phospholipase A2 G12B expression.

PubMed

Liu, Qingli; Yang, Meng; Fu, Xuekun; Liu, Renzhong; Sun, Caijun; Pan, Haobo; Wong, Chi-Wai; Guan, Min

2016-11-15

As a novel mediator of hepatic very low-density lipoproteins (VLDL) secretion, phospholipase A2 G12B (PLA2G12B) is transcriptionally regulated by hepatocyte nuclear factor-4 alpha (HNF-4α). Farnesoid X receptor (FXR) plays a critical role in maintaining bile acids and triglycerides (TG) homeostasis. Here we report that FXR regulates serum TG level in part through PLA2G12B. Activation of FXR by chenodeoxycholic acid (CDCA) or GW4064 significantly decreased PLA2G12B expression in HepG2 cells. PLA2G12B expression was transcriptionally repressed due to an FXR-mediated up-regulation of small heterodimer partner (SHP) which functionally suppresses HNF-4α activity. We found that hepatic PLA2G12B expression was suppressed and serum TG level reduced in high fat diet mice treated with CDCA. Concurrently, CDCA treatment lowered hepatic VLDL-TG secretion. Our data demonstrate that activation of FXR promotes TG lowering, not only by decreasing de novo lipogenesis but also reducing hepatic secretion of TG-rich VLDL particles in part through suppressing PLA2G12B expression. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

A mid-twentieth century reduction in tropical upwelling inferred from coralline trace element proxies

NASA Astrophysics Data System (ADS)

Reuer, Matthew K.; Boyle, Edward A.; Cole, Julia E.

2003-05-01

The Cariaco Basin is an important archive of past climate variability given its response to inter- and extratropical climate forcing and the accumulation of annually laminated sediments within an anoxic water column. This study presents high-resolution surface coral trace element records ( Montastrea annularis and Siderastrea siderea) from Isla Tortuga, Venezuela, located within the upwelling center of this region. A two-fold reduction in Cd/Ca ratios (3.5-1.7 nmol/mol) is observed from 1946 to 1952 with no concurrent shift in Ba/Ca ratios. This reduction agrees with the hydrographic distribution of dissolved cadmium and barium and their expected response to upwelling. Significant anthropogenic variability is also observed from Pb/Ca analysis, observing three lead maxima since 1920. Kinetic control of trace element ratios is inferred from an interspecies comparison of Cd/Ca and Ba/Ca ratios (consistent with the Sr/Ca kinetic artifact), but these artifacts are smaller than the environmental signal and do not explain the Cd/Ca transition. The trace element records agree with historical climate data and differ from sedimentary faunal abundance records, suggesting a linear response to North Atlantic extratropical forcing cannot account for the observed historical variability in this region.

Behavior of atypical amphiphilic molecules

NASA Astrophysics Data System (ADS)

Ko, John

1997-08-01

The physical behavior of several atypical amphiphilic molecules was studied in various environments including micelles, model bilayer membranes, and emulsions. The molecules under investigation were nor-chenodeoxycholic acid (nor-CDCA), ursodeoxycholic acid (UDCA), sphingosine (Sp), sphingosine hydrochloride (SpċHCl), and tetrahydrolipstatin (THL). The bile acids, nor-CDCA and UDCA, were studied using 13C-Nuclear Magnetic Resonance ([13C) -NMR) in micelles of taurocholate and in bilayers of phosphatidylcholine. The pK a values of the bile acids in each environment were determined by [13C) -NMR and are as follows: 6.08 ±.03 for nor-CDCA and 6.27 ±.01 for UDCA in micelles, and 7.04 ± 12 for nor-CDCA and 6.89 ±.05 for UDCA in vesicles. Using line shape analysis, the transbilayer movement rate at 36oC for nor-CDCA and UDCA was calculated to be 580 sec--1 and 409 sec-1, respectively. [13C) -NMR titration of Sp gave pK a values of 9.09 ±.02 in micelles and 9.69 ±.21 in bilayers. Differential scanning calorimetry (DSC) and X-ray diffraction were used to establish the Spċwater and SpċHClċwater phase diagrams. Anhydrous and hydrated samples ranging from 5- 90% water were analyzed. The DSC thermograms traced out the transition temperatures of each molecule while the X- ray diffraction patterns revealed their chain and crystalline lattice packing structures. In general, sphingosine exists as a hydrated crystal with β packing phase below 43oC and melts into an Lα phase. Sphingosine hydrochloride, however, exists as a gel phase (L_beta or /beta/sp') below 42oC that swells to 61% hydration. At low water concentrations (0-64%), a lamellar liquid crystal phase (L_alpha) is formed above the chain melting transition of 42oC. At medium concentration (65%), a Hexagonal I phase is present, and at high water concentrations (66-90%), a micellar phase is present. THL, a specific inhibitor of lipases, was analyzed with [ 13C) -NMR to study its behavior in various environments, ranging from carbon tetrachloride to water to pure triolein. THL was also incorporated into phosphatidylcholine bilayers and into microemulsions of triolein and phosphatidylcholine. [ 13C) -NMR analysis revealed that THL gets incorporated into the surface of vesicles, and into both the surface and core of microemulsion particles.

Mineral resources of the Fort Piute Wilderness Study Area, San Bernardino County, California

USGS Publications Warehouse

Nielson, Jane E.; Frisken, James G.; Jachens, Robert C.; McDonnell, John R.

1987-01-01

The Fort Piute Wilderness Study Area (CDCA-267) is in northeastern San Bernardino County, California, near the boundary between California and Nevada. Mineral surveys were requested for 31,371 acres of the Fort Piute Wilderness Study Area. In this report the area studied is referred to as "the study area". Examination of mines and prospects in the area was accomplished by the U.S. Bureau of Mines in 1981 and 1982. Field investigations of the area were carried out by the U.S. Geological Survey in 1983 and 1985. No mines or prospects, few mining claims, and no identified resources are located within the wilderness study area. Moderate and low potential for gold resources appears limited to outcrops of gneiss and granite exposed along the eastern side of the Piute Range. Available information indicates that there is no potential for energy resources, including oil and gas, uranium, or geothermal, in the study area.

Geochemical studies in the Indian Pass and Picacho Peak Bureau of Land Management Wilderness study areas, imperial county, Southern California

USGS Publications Warehouse

Smith, D.B.; Berger, B.R.; Tosdal, R.M.

1987-01-01

The U.S. Geological Survey has conducted geochemical studies in the Indian Pass (CDCA-355), 124 km2, and Picacho Peak (CDCA-355A), 23 km2, Wilderness Study Areas (WSA's) as part of a program to evaluate the mineral resource potential of designated areas in the California Desert Conservation Area. These two WSA's are of particular interest because they lie within a region which has intermittently produced significant quantities of Au since the mid-1800's, and is currently the site of much exploration activity for additional Au resources. Within a 15-km radius of the WSA's, there is one actively producing gold mine, a major deposit which began production in 1986, and one recently announced discovery. In the reconnaissance geochemical surveys of the two WSA's - 177 ??m (-80 mesh) stream sediments, heavy-mineral concentrates from stream sediments, and rocks were prepared and analyzed. Four areas of possible exploration interest were identified within the WSA's. The first area is characterized by anomalous W and Bi in nonmagnetic heavy-mineral concentrates, and is underlain primarily by the Mesozoic Orocopia Schist which has been intruded by monzogranite of Oligocene age. Alteration and mineralization appear to be localized near the intrusive contact. The mineralized rock at the surface contains secondary Cu and Fe minerals where the monzogranite intrudes the metabasite horizons of the Orocopia Schist and scheelite where the monzogranite intrudes marble within the Orocopia Schist. The second area is characterized by anomalous As, Sb, Ba, B, and Sr in nonmagnetic heavy-mineral concentrates and by anomalous As in - 177 ??m stream sediments. Geologically, this area is underlain by metasedimentary and metavolcanic rocks of Jurassic(?) age; a biotite monzogranite of Jurassic(?) age; and Tertiary volcanic and hypabyssal rocks composed of flows, domes, and tuffs of intermediate to silicic composition. All these rock types are cut by a set of north-south-striking normal faults. The anomalies in the heavy-mineral concentrates are believed to be related to silica-clay alteration observed in the vicinity of some of these faults. ?? 1987.

Trace element evidence for abrupt changes in deep South Atlantic Ocean nutrient and carbonate chemistry across the Mid-Pleistocene Transition

NASA Astrophysics Data System (ADS)

Farmer, J. R.; Hoenisch, B.; Haynes, L.; Kroon, D.; Bell, D. B.; Jung, S.; Seguí, M. J.; Raymo, M. E.; Goldstein, S. L.; Pena, L. D.

2016-12-01

Pleistocene glaciations underwent a profound transition from lower amplitude 40 kyr cycles to high amplitude 100 kyr cycles between 1.2 and 0.8 Ma, an interval termed the Mid-Pleistocene Transition (MPT). While the underlying causes of the MPT are uncertain, previous studies show quasi-contemporaneous reductions in North Atlantic Deep Water (NADW) export1 and glacial atmospheric pCO22 around 0.9 Ma. Although this suggests a possible role for enhanced deep-ocean carbon storage in amplifying climate change across the MPT, few direct records of deep ocean carbonate chemistry exist for this interval to test this hypothesis. Here we present South Atlantic benthic foraminiferal B/Ca and Cd/Ca records from International Ocean Discovery Program Sites 1088, 1264 and 1267 (2.1 to 4.3 km water depth) as part of a larger study of Atlantic-wide changes in deep ocean chemistry and circulation spanning the MPT. Results show an abrupt 15-20% decrease in benthic B/Ca and 40-50% increase in Cd/Ca at 4.3 km depth (Site 1267) between 1.0 and 0.9 Ma. Site 1088, which at 2.1 km depth is sensitive to input of southern-sourced Upper Circumpolar Deep Water, shows a prolonged 25% decrease in B/Ca and 50% increase in Cd/Ca from 1.0 to 0.6 Ma. In contrast, at Site 1264 ( 2.5 km depth within the core of modern NADW) B/Ca and Cd/Ca changes across the MPT are more modest (-5% and +10%, respectively). These observations reflect on the accumulation of regenerated carbon and nutrients in the deep South Atlantic, and varying contributions of northern- and southern-sourced watermasses to each core site. Implications for deep-ocean carbon storage and forcing of the MPT will be discussed. 1Pena, L. and Goldstein, S. (2014), Science 345, 318 2Hönisch, B. et al. (2009), Science 324, 1551

Biliary Bile Acids in Primary Biliary Cirrhosis: Effect of Ursodeoxycholic Acid

PubMed Central

Combes, Burton; Carithers, Robert L.; Maddrey, Willis C.; Munoz, Santiago; Garcia-Tsao, Guadalupe; Bonner, Gregory F.; Boyer, James L.; Luketic, Velimir A.; Shiffman, Mitchell L.; Peters, Marion G.; White, Heather; Zetterman, Rowen K.; Risser, Richard; Rossi, Stephen S.; Hofmann, Alan F.

2014-01-01

Bile acid composition in fasting duodenal bile was assessed at entry and at 2 years in patients with primary biliary cirrhosis (PBC) enrolled in a randomized, double-blind, placebo-controlled trial of ursodeoxycholic acid (UDCA) (10–12 mg/kg/d) taken as a single bedtime dose. Specimens were analyzed by a high-pressure liquid chromatography method that had been validated against gas chromatography. Percent composition in bile (mean ± SD) for 98 patients at entry for cholic (CA), chenodeoxycholic (CDCA), deoxycholic (DCA), lithocholic (LCA), and ursodeoxycholic (UDCA) acids, respectively, were 57.4 ± 18.6, 31.5 ± 15.5, 8.0 ± 9.3, 0.3 ± 1.0, and 0.6 ± 0.9. Values for CA were increased, whereas those for CDCA, DCA, LCA, and UDCA were decreased when compared with values in normal persons. Bile acid composition of the major bile acids did not change after 2 years on placebo medication. By contrast, in patients receiving UDCA for 2 years, bile became enriched with UDCA on average to 40.1%, and significant decreases were noted for CA (to 32.2%) and CDCA (to 19.5%). No change in percent composition was observed for DCA and LCA. Percent composition at entry and changes in composition after 2 years on UDCA were similar in patients with varying severity of PBC. In patients whose bile was not enriched in UDCA (entry and placebo-treated specimens), CA, CDCA, DCA, and the small amount of UDCA found in some of these specimens were conjugated to a greater extent with glycine (52%–64%) than with taurine (36%–48%). Treatment with UDCA caused the proportion of all endogenous bile acids conjugated with glycine to increase to 69% to 78%, while the proportion conjugated with taurine (22%–31%) fell (P < .05). Administered UDCA was also conjugated predominantly with glycine (87%). PMID:10347103

A novel methodology to investigate isotopic biosignatures

NASA Astrophysics Data System (ADS)

Horner, T. J.; Lee, R. B. Y.; Henderson, G. M.; Rickaby, R. E. M.

2012-04-01

An enduring goal of trace metal isotopic studies of Earth History is to find isotopic 'fingerprints' of life or of life's individual physiochemical processes. Generally, such signatures are sought by relating an isotopic effect observed in controlled laboratory conditions or a well-characterized environment to a more complex system or the geological record. However, such an approach is ultimately limited because life exerts numerous isotopic fractionations on any one element so it is hard to dissect the resultant net fractionation into its individual components. Further, different organisms, often with the same apparent cellular function, can express different isotopic fractionation factors. We have used a novel method to investigate the isotopic fractionation associated with a single physiological process-enzyme specific isotopic fractionation. We selected Cd isotopes since only one biological use of Cd is known, CdCA (a Cd/Zn carbonic anhydrase from the coastal diatom T. Weissflogii). Thus, our investigation can also inform the long standing mystery as to why this generally toxic element appears to have a nutrient-like dissolved isotopic and concentration profile in the oceans. We used the pET-15b plasmid to insert the CdCA gene into the E. coli genome. There is no known biochemical function for Cd in E. coli, making it an ideal vector for studying distinct physiological processes within a single organism. The uptake of Cd and associated isotopic fractionation was determined for both normal cells and those expressing CdCA. It was found that whole cells always exhibited a preference for the light isotopes of Cd, regardless of the expression of CdCA; adsorption of Cd to cell surfaces was not seen to cause isotopic fractionation. However, the cleaning procedure employed exerted a strong control on the observed isotopic composition of cells. Using existing protein purification techniques, we measured the Cd isotopic composition of different subcellular fractions of E. coli (e.g. membranes, cytosol, etc.), including the catalytic metal atoms within CdCA. These experiments allow isotopic exchange reactions to be observed in biological systems at an unparalleled resolution, demonstrating that isotopic fractionation can occur, in vivo, on length scales as small as a few Å. We will explore future applications of this technique using the marine geochemistry of Cd as a case study. This experimental approach has great promise for studying the individual isotopic biosignatures of other biochemical reactions, in particular those which may have been active during early Earth History.

Individual bile acids have differential effects on bile acid signaling in mice

DOE Office of Scientific and Technical Information (OSTI.GOV)

Song, Peizhen, E-mail: songacad@gmail.com; Rockwell, Cheryl E., E-mail: rockwelc@msu.edu; Cui, Julia Yue, E-mail: juliacui@uw.edu

2015-02-15

Bile acids (BAs) are known to regulate BA synthesis and transport by the farnesoid X receptor in the liver (FXR-SHP) and intestine (FXR-Fgf15). However, the relative importance of individual BAs in regulating these processes is not known. Therefore, mice were fed various doses of five individual BAs, including cholic acid (CA), chenodeoxycholic acid (CDCA), deoxoycholic acid (DCA), lithocholic acid (LCA), and ursodeoxycholic acid (UDCA) in their diets at various concentrations for one week to increase the concentration of one BA in the enterohepatic circulation. The mRNA of BA synthesis and transporting genes in liver and ileum were quantified. In themore » liver, the mRNA of SHP, which is the prototypical target gene of FXR, increased in mice fed all concentrations of BAs. In the ileum, the mRNA of the intestinal FXR target gene Fgf15 was increased at lower doses and to a higher extent by CA and DCA than by CDCA and LCA. Cyp7a1, the rate-limiting enzyme in BA synthesis, was decreased more by CA and DCA than CDCA and LCA. Cyp8b1, the enzyme that 12-hydroxylates BAs and is thus responsible for the synthesis of CA, was decreased much more by CA and DCA than CDCA and LCA. Surprisingly, neither a decrease in the conjugated BA uptake transporter (Ntcp) nor increase in BA efflux transporter (Bsep) was observed by FXR activation, but an increase in the cholesterol efflux transporter (Abcg5/Abcg8) was observed with FXR activation. Thus in conclusion, CA and DCA are more potent FXR activators than CDCA and LCA when fed to mice, and thus they are more effective in decreasing the expression of the rate limiting gene in BA synthesis Cyp7a1 and the 12-hydroxylation of BAs Cyp8b1, and are also more effective in increasing the expression of Abcg5/Abcg8, which is responsible for biliary cholesterol excretion. However, feeding BAs do not alter the mRNA or protein levels of Ntcp or Bsep, suggesting that the uptake or efflux of BAs is not regulated by FXR at physiological and pharmacological concentrations of BAs. - Highlights: • All four major bile acids in humans activate the FXR in liver and intestine. • These bile acids decreased the mRNA of the bile acid synthetic enzymes Cyp7a1 and Cyp8b1. • These BAs did not alter the mRNA or protein of the conjugated BA transporters (Ntcp and Bsep). • Cholic acid and deoxycholic acid are more potent activators of FXR than chenodeoxycholic acid and lithocholic acid.« less

Bile acid receptor TGR5 overexpression is associated with decreased intestinal mucosal injury and epithelial cell proliferation in obstructive jaundice.

PubMed

Ji, Chen-Guang; Xie, Xiao-Li; Yin, Jie; Qi, Wei; Chen, Lei; Bai, Yun; Wang, Na; Zhao, Dong-Qiang; Jiang, Xiao-Yu; Jiang, Hui-Qing

2017-04-01

Bile acids stimulate intestinal epithelial proliferation in vitro. We sought to investigate the role of the bile acid receptor TGR5 in the protection of intestinal epithelial proliferation in obstructive jaundice. Intestinal tissues and serum samples were obtained from patients with malignant obstructive jaundice and from bile duct ligation (BDL) rats. Intestinal permeability and morphological changes in the intestinal mucosa were observed. The functions of TGR5 in cell proliferation in intestinal epithelial injury were determined by overexpression or knockdown studies in Caco-2 and FHs 74 Int cells pretreated with lipopolysaccharide (LPS). Internal biliary drainage was superior to external biliary drainage in recovering intestinal permeability and mucosal histology in patients with obstructive jaundice. In BDL rats, feeding of chenodeoxycholic acid (CDCA) decreased intestinal mucosa injury. The levels of PCNA, a marker of proliferation, increased in response to CDCA feeding and were paralleled by elevated TGR5 expression. CDCA upregulated TGR5 expression and promoted proliferation in Caco-2 and FHs 74 Int cells pretreated with LPS. Overexpression of TGR5 resulted in increased PCNA, cell viability, EdU incorporation, and the proportion of cells in S phase, whereas knockdown of TGR5 had the opposite effect. Our data indicate that bile acids promote intestinal epithelial cell proliferation and decrease mucosal injury by upregulating TGR5 expression in obstructive jaundice. Copyright © 2016 Elsevier Inc. All rights reserved.

Multi-proxy Reconstructions of Deglacial Variability of Antarctic Intermediate Water Circulation in the Western Tropical Atlantic

NASA Astrophysics Data System (ADS)

Huang, K.; Oppo, D.; Curry, W. B.

2012-12-01

Reconstruction of changes in Antarctic Intermediate Water (AAIW) circulation across the last deglaciation is critical in constraining the links between AAIW and Atlantic Meridional Overturning Circulation (AMOC) and understanding how AAIW influences oceanic heat transport and carbon budget across abrupt climate events. Here we systematically establish in situ calibrations for carbonate saturation state (B/Ca), nutrient (Cd/Ca and δ13C) and watermass proxies (ɛNd) in foraminifera using multicore tops and ambient seawater samples collected from the Demerara Rise, western tropical Atlantic. Through the multi-proxy reconstructions, deglacial variability of intermediate water circulation in the western tropical Atlantic can be further constrained. The reconstructed seawater Cd record from the Demerara Rise sediment core (KNR197-3-46CDH, at 947 m water depth) over the last 21 kyrs suggests reduced presence of AAIW during the cold intervals (LGM, H1 and YD) when AMOC was reduced. Down-core B/Ca record shows elevated intermediate water Δ[CO32-] during these cold intervals, further indicating a weaker influence of AAIW in the western tropical Atlantic. The δ13C record exhibits a pronounced deglacial minimum and a clear decoupling between δ13C and Cd/Ca after the AMOC completely recovered at around 8 kyr BP. This could be due to the carbonate ion effect on benthic Cd/Ca or the influence of organic matter remineralization on benthic δ13C. A new ɛNd record for the last deglaciation will be provided to evaluate the relative proportions of southern and northern waters at this intermediate site in the western tropical Atlantic.

Validation of cooking times and temperatures for thermal inactivation of Yersinia pestis strains KIM5 and CDC-A1122 in irradiated ground beef.

PubMed

Porto-Fett, Anna C S; Juneja, Vijay K; Tamplin, Mark L; Luchansky, John B

2009-03-01

Irradiated ground beef samples (ca. 3-g portions with ca. 25% fat) inoculated with Yersina pestis strain KIM5 (ca. 6.7 log CFU/g) were heated in a circulating water bath stabilized at 48.9, 50, 52.5, 55, 57.5, or 60 degrees C (120, 122, 126.5, 131, 135.5, and 140 degrees F, respectively). Average D-values were 192.17, 34.38, 17.11, 3.87, 1.32, and 0.56 min, respectively, with a corresponding z-value of 4.67 degrees C (8.41 degrees F). In related experiments, irradiated ground beef patties (ca. 95 g per patty with ca. 25% fat) were inoculated with Y. pestis strains KIMS or CDC-A1122 (ca. 6.0 log CFU/g) and cooked on an open-flame gas grill or on a clam-shell type electric grill to internal target temperatures of 48.9, 60, and 71.1 degrees C (120, 140, and 160 degrees F, respectively). For patties cooked on the gas grill, strain KIM5 populations decreased from ca. 6.24 to 4.32, 3.51, and < or = 0.7 log CFU/g at 48.9, 60, and 71.1 degrees C, respectively, and strain CDC-A1122 populations decreased to 3.46 log CFU/g at 48.9 degrees C and to < or = 0.7 log CFU/g at both 60 and 71.1 degrees C. For patties cooked on the clam-shell grill, strain KIM5 populations decreased from ca. 5.96 to 2.53 log CFU/g at 48.9 degrees C and to < or = 0.7 log CFU/g at 60 or 71.1 degrees C, and strain CDC-A1122 populations decreased from ca. 5.98 to < or = 0.7 log CFU/g at all three cooking temperatures. These data confirm that cooking ground beef on an open-flame gas grill or on a clam-shell type electric grill to the temperatures and times recommended by the U.S. Department of Agriculture and the U.S. Food and Drug Administration Food Code, appreciably lessens the likelihood, severity, and/or magnitude of consumer illness if the ground beef were purposefully contaminated even with relatively high levels of Y. pestis.

Mineral resources of the Castle Peaks Wilderness Study Area, San Bernardino County, California

USGS Publications Warehouse

Miller, David A.W.; Frisken, James G.; Jachens, Robert C.; Gese, Diann D.

1986-01-01

The Castle Peaks Wilderness Study Area (CDCA266) comprises approximately 45,000 acres in the northern New York Mountains, San Bernardino County, California. At the request of the Bureau of Land Management, 39,303 acres of the wilderness study area were studied. The area was investigated during 1982-1985 using combined geologic, geochemical, and geophysical methods. are considered preliminarily suitable for wilderness deignation. There are no mineral reserves or identified resources in the study area. Fluorspar, occurring in sparse veins, has moderate resource potential, as do silver and lead in fault zones, and gold and silver in sparse, high-grade veins and fault breccia. Each area of moderate resource potential encompasses less than one square mile. These same commodities have low resource potential in similar occurrences throughout much of the study area. In addition, there is low resource potential for gold in placer deposits, uranium in altered breccia and gouge, and rare-earth elements in pegmatite dikes. There is no resource potential for oil and gas resources over most of the study area, but the potential is unknown along its western margin. In this report, the area studied is referred to"the wilderness study area", or simply "the study area."

The organic solute transporters alpha and beta are induced by hypoxia in human hepatocytes

PubMed Central

Schaffner, Carlos A; Mwinyi, Jessica; Gai, Zhibo; Thasler, Wolfgang E; Eloranta, Jyrki J; Kullak-Ublick, Gerd A

2015-01-01

Background & Aims The organic solute transporters alpha and beta (OSTα-OSTβ) form a heterodimeric transporter located at the basolateral membrane of intestinal epithelial cells and hepatocytes. Liver injury caused by ischaemia-reperfusion, cancer, inflammation or cholestasis can induce a state of hypoxia in hepatocytes. Here, we studied the effect of hypoxia on the expression of OSTα-OSTβ. Methods OSTα-OSTβ expression was measured in Huh7 cells and primary human hepatocytes (PHH) exposed to chenodeoxycholic acid (CDCA), hypoxia or both. OSTα-OSTβ promoter activity was analysed in luciferase reporter gene assays. Binding of hypoxia-inducible factor-1 alpha (HIF-1α) to the OSTα-OSTβ gene promoters was studied in electrophoretic mobility shift assays (EMSA). Results Expression of OSTα and OSTβ increased in PHH under conditions of hypoxia. Exposure of Huh7 cells or PHH to CDCA (50 μM) enhanced the effect of hypoxia on OSTα mRNA levels. In luciferase assays and EMSA, the inducing effect of low oxygen could be assigned to HIF-1α, which binds to hypoxia responsive elements (HRE) in the OSTα and OSTβ gene promoters. Site-directed mutagenesis of either the predicted HRE or the bile acid responsive FXR binding site abolished inducibility of the OSTα promoter, indicating that both elements need to be intact for induction by hypoxia and CDCA. In a rat model of chronic renal failure, the known increase in hepatic OSTα expression was associated with an increase in HIF-1α protein levels. Conclusion OSTα-OSTβ expression is induced by hypoxia. FXR and HIF-1α bind in close proximity to the OSTα gene promoter and produce synergistic effects on OSTα expression. PMID:24703425

Intracellular Cadmium Isotope Fractionation

NASA Astrophysics Data System (ADS)

Horner, T. J.; Lee, R. B.; Henderson, G. M.; Rickaby, R. E.

2011-12-01

Recent stable isotope studies into the biological utilization of transition metals (e.g. Cu, Fe, Zn, Cd) suggest several stepwise cellular processes can fractionate isotopes in both culture and nature. However, the determination of fractionation factors is often unsatisfactory, as significant variability can exist - even between different organisms with the same cellular functions. Thus, it has not been possible to adequately understand the source and mechanisms of metal isotopic fractionation. In order to address this problem, we investigated the biological fractionation of Cd isotopes within genetically-modified bacteria (E. coli). There is currently only one known biological use or requirement of Cd, a Cd/Zn carbonic anhydrase (CdCA, from the marine diatom T. weissfloggii), which we introduce into the E. coli genome. We have also developed a cleaning procedure that allows for the treating of bacteria so as to study the isotopic composition of different cellular components. We find that whole cells always exhibit a preference for uptake of the lighter isotopes of Cd. Notably, whole cells appear to have a similar Cd isotopic composition regardless of the expression of CdCA within the E. coli. However, isotopic fractionation can occur within the genetically modified E. coli during Cd use, such that Cd bound in CdCA can display a distinct isotopic composition compared to the cell as a whole. Thus, the externally observed fractionation is independent of the internal uses of Cd, with the largest Cd isotope fractionation occurring during cross-membrane transport. A general implication of these experiments is that trace metal isotopic fractionation most likely reflects metal transport into biological cells (either actively or passively), rather than relating to expression of specific physiological function and genetic expression of different metalloenzymes.

CDCA7L and Mechanisms of Increased Male Bias in Glioma

DTIC Science & Technology

2017-05-01

described in the previous annual report, these tasks will be replaced by the direct engineering of cells using CRISPR technology. Task 8: Test...knockdown of transcription factors and CRISPR modification of SNPs in transcription factor binding sites. This will help us understand whether

Enteral obeticholic acid promotes intestinal growth in total parenteral nutrition fed neonatal pigs

USDA-ARS?s Scientific Manuscript database

Intestinal atrophy is an adverse outcome associated with prolonged total parenteral nutrition (PN) partly due to disruption of normal enterohepatic circulation of bile acids. Previously we showed that enteral treatment with chenodeoxycholic acid (CDCA), a dual agonist for the nuclear receptor, farne...

Targeted Approaches to Overcoming Endocrine Resistance in Breast Cancer

DTIC Science & Technology

2011-08-01

NM_001012271 BUB1 BUB1 budding uninhibited by benzimidazoles 1 homolog AF053305 CDC20 Cell division cycle 20 homolog BG256659 CDC25B Cell division cycle...by benzimidazoles 1 homolog), BIRC5/ Survivin, CDCA8 (cell division cycle-associated protein 8), AURKB (aurora kinase B), CDC25B (cell division cycle

Targeted Approaches to Overcoming Endocrine Resistance in Breast Cancer

DTIC Science & Technology

2012-08-01

kinase B CD049340 BIRC5 Effector cell peptidase receptor 1 NM_001012271 BUB1 BUB1 budding uninhibited by benzimidazoles 1 homolog AF053305 CDC20 Cell...P ≤ 0.0001). Among these were BUB1 (bud- ding uninhibited by benzimidazoles 1 homolog), BIRC5/ Survivin, CDCA8 (cell division cycle-associated

Simultaneous Determination of Ursodeoxycholic Acid and Chenodeoxycholic Acid in Pharmaceutical Dosage Form by HPLC-UV Detection.

PubMed

Khairy, Mostafa A; Mansour, Fotouh R

2017-01-01

A reversed-phase HPLC method was developed for the simultaneous determination of ursodeoxycholic acid (UDCA) and the epimeric isomer, chenodeoxycholic acid (CDCA), in their synthetic mixtures and in tablet dosage form. The proposed HPLC method uses a C18 column and mobile phase consisting of an acetonitrile-phosphate buffer mixture (pH 2.3, 100 mM; 50 + 50, v/v) at a flow rate of 2.0 mL/min with UV detection at 210 nm. The method was validated according to the International Conference on Harmonization guidelines; and linearity, range, accuracy, precision, robustness, and system suitability were studied. The LOD and LOQ were also calculated and found to be 1.23 and 3.73 μg/mL for UDCA and 0.83 and 2.52 μg/mL for CDCA, respectively. The method was adapted for UHPLC, in which baseline separation was achieved in <2.5 min. The assay results of Ursomix tablets by the developed method were statistically compared with those obtained by the reference method using t- and F-tests, and no significant differences were observed.

Profiling serum bile acid glucuronides in humans: gender divergences, genetic determinants and response to fenofibrate

PubMed Central

Trottier, Jocelyn; Perreault, Martin; Rudkowska, Iwona; Levy, Cynthia; Dallaire-Theroux, Amélie; Verreault, Mélanie; Caron, Patrick; Staels, Bart; Vohl, Marie-Claude; Straka, Robert J.; Barbier, Olivier

2014-01-01

Glucuronidation, catalyzed by UDP-glucuronosyltransferase (UGT) enzymes detoxifies cholestatic bile acids (BAs). We aimed at i) characterizing the circulating BA-glucuronide (-G) pool composition in humans, ii) evaluating how sex and UGT polymorphisms influence this composition, and iii) analyzing the effects of lipid-lowering drug fenofibrate on the circulating BA-G profile in 300 volunteers and 5 cholestatic patients. Eleven BA-Gs were determined in pre- and post-fenofibrate samples. Men exhibited higher BA-G concentrations, and various genotype/BA-G associations were discovered in relevant UGT genes. The chenodeoxycholic acid-3G concentration was associated with the UGT2B7 802C>T polymorphism. Glucuronidation assays confirmed the predominant role of UGT2B7 and UGT1A4 in CDCA-3G formation. Fenofibrate exposure increased the serum levels of 5 BA-G species, including CDCA-3G, and up-regulated expression of UGT1A4, but not UGT2B7, in hepatic cells. This study demonstrates that fenofibrate stimulates BA glucuronidation in humans, and thus reduces bile acid toxicity in the liver. PMID:23756370

Molecular Analysis of Congenital Hypothyroidism in Saudi Arabia: SLC26A7 Mutation Is a Novel Defect in Thyroid Dyshormonogenesis.

PubMed

Zou, Minjing; Alzahrani, Ali S; Al-Odaib, Ali; Alqahtani, Mohammad A; Babiker, Omer; Al-Rijjal, Roua A; BinEssa, Huda A; Kattan, Walaa E; Al-Enezi, Anwar F; Al Qarni, Ali; Al-Faham, Manar S A; Baitei, Essa Y; Alsagheir, Afaf; Meyer, Brian F; Shi, Yufei

2018-05-01

Congenital hypothyroidism (CH) is the most common neonatal endocrine disorder, affecting one in 3000 to 4000 newborns. Since the introduction of a newborn screening program in 1988, more than 300 cases have been identified. The underlying genetic defects have not been systematically studied. To identify the mutation spectrum of CH-causing genes. Fifty-five patients from 47 families were studied by next-generation exome sequencing. Mutations were identified in 52.7% of patients (29 of 55) in the following 11 genes: TG, TPO, DUOX2, SLC26A4, SLC26A7, TSHB, TSHR, NKX2-1, PAX8, CDCA8, and HOXB3. Among 30 patients with thyroid dyshormonogenesis, biallelic TG mutations were found in 12 patients (40%), followed by biallelic mutations in TPO (6.7%), SLC26A7 (6.7%), and DUOX2 (3.3%). Monoallelic SLC26A4 mutations were found in two patients, one of them coexisting with two tandem biallelic deletions in SLC26A7. In 25 patients with thyroid dysgenesis, biallelic mutations in TSHR were found in six patients (24%). Biallelic mutations in TSHB, PAX 8, NKX2-1, or HOXB3 were found once in four different patients. A monoallelic CDCA8 mutation was found in one patient. Most mutations were novel, including three TG, two TSHR, and one each in DUOX2, TPO, SLC26A7, TSHB, NKX2-1, PAX8, CDCA8, and HOXB3. SLC26A7 and HOXB3 were novel genes associated with thyroid dyshormonogenesis and dysgenesis, respectively. TG and TSHR mutations are the most common genetic defects in Saudi patients with CH. The prevalence of other disease-causing mutations is low, reflecting the consanguineous nature of the population. SLC26A7 mutations appear to be associated with thyroid dyshormonogenesis.

76 FR 5396 - Notice of Intent To Prepare an Environmental Impact Statement for the Proposed Rising Tree Wind...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-31

...] Notice of Intent To Prepare an Environmental Impact Statement for the Proposed Rising Tree Wind Farm... on issues and alternatives related to the Rising Tree Wind Farm Draft EIS/EIR and possible CDCA PA by...-megawatt Rising Tree Wind Farm. The proposed project is approximately three miles west of the town of...

Analytical results and sample locality map of heavy-mineral-concentrate and rock samples from the Castle Peaks Wilderness Study Area (CDCA- 266), San Bernardino County, California

USGS Publications Warehouse

Adrian, B.M.; Frisken, J.G.; Malcolm, M.J.; Crock, J.G.

1986-01-01

The report presents water-quality and geohydrologic information for 106 public water-supply wells in Illinois. These wells were sampled during April to December 1984 as part of a pilot program to develop a ground-water observation network in the State. The pilot program was designed to sample single-aquifer wells from three major aquifer systems--(1) sand and gravel, both confined and unconfined; (2) Silurian dolomite; and (3) the Ironton-Galesville deep sandstone. Data are tabulated for water temperature, pH, specific conductance, oxidation-reduction potential, ammonia nitrogen, nitrate + nitrite nitrogen, phosphorus, silica, arsenic, lead, mercury, fluoride, chloride, sulfate, cyanide, phenols, selenium, residue on evaporation at 180 degrees Celsius, alkalinity, calcium, magnesium, sodium, potassium, barium, boron, beryllium, cadmium, chormium, copper, cobalt, iron, aluminum, manganese, nickel, silver, strontium, vanadium, zinc, and selected geohydrologic information.

Analytical results and sample locality map of heavy-mineral- concentrate and rock samples from the Kingston Range Wilderness Study Area (CDCA-222), San Bernardino County, California

USGS Publications Warehouse

Adrian, B.M.; Frisken, J.G.; Malcolm, M.J.; Crock, J.G.; Briggs, P.H.

1986-01-01

During 1984, 60 stream sites were sampled for the presence of Giardia sp. cysts. The sampling sites ranged in elevation from 6 ,000 to 12,000 feet, and were distributed over a distance of more than 200 miles, from the Lake Tahoe basin in the north to Mt. Whitney in the south. Cysts of Giardia were detected in 27 of 78 samples. The number of cysts detected ranged from 1 to 41. Of the 27 samples positive for Giardia, only 1 cyst was detected in each of 10 samples, 2 cysts were detected in each of 8 samples, 3 cysts were detected in each of 3 samples, 4 cysts were detected in each of 2 samples, and 5, 6, 14, and 41 cysts were detected in 1 sample each. (USGS)

[Rapid identification of two new isomers in bear bile powder by LC-Q-TOF-MS combined with PCC oxidation].

PubMed

Jian, Long-Hai; Hu, Chun; Yu, Hong; Wang, Ke; Ji, Shen

2013-07-01

A rapid method of Liquid chromatography-quadrupole time-of-flight mass spectrometry (LC-Q-TOF-MS) combined with pyridinium chlorochromate (PCC) oxidation has been developed to determine chemical structures of two novel isomers in bear bile powder. Derivatives of ursodeoxycholic acid (UDCA) and chenodeoxycholic acid (CDCA) were semi-synthesized by PCC oxidation, then were analyzed by LC-Q-TOF-MS. Separation was carried out on a reverse column with the mobile phase of acetonitrile-0.1% formic acid (45:55). The data of Q-TOF-MS was acquired by MS, MS/MS, positive and negative modes. Since UDCA and CDCA were stereochemical isomeric at an alcohol position, two oxidation products were same and have been confirmed by LC-Q-TOF-MS. Other two products were also determined based on the PCC oxidation theory. Samples of bear bile powder were dissolved by methanol and measured by LC-Q-TOF-MS. Two unknown peaks were found and identified by matching their retention times and accurate mass spectra ions with PCC oxidation productS. Finally, the structures of two new bile acids in bear bile powder were confirmed as 3alpha-hydroxy-7-oxo-5beta-cholanic acid, 7alpha-hydroxy-3-oxo-5beta-cholanic acid, respectively.

Mineral resources of the Turtle Mountains Wilderness Study Area, San Bernardino County, California

USGS Publications Warehouse

Howard, Keith A.; Nielson, Jane E.; Simpson, Robert W.; Hazlett, Richard W.; Alminas, Henry V.; Nakata, John K.; McDonnell, John R.

1988-01-01

At the request of the U.S. Bureau of Land Management, approximately 105,200 acres of the Turtle Mountains Wilderness Study Area (CDCA-307) were evaluated for mineral resources (known) and resource potential (undiscovered). In this report, the area studied is referred to as "the wilderness study area" or simply "the study area"; any reference to the Turtle Mountain Wilderness Study Area refers only to that part of the wilderness study area for which a mineral survey was requested by the U.S. Bureau of Land Management.The wilderness study area is in southeastern San Bernardino County, Calif. Gold, silver, copper, and lead have been mined within and adjacent to the study area. Copper-zinc-silver-gold mineral occurrences are found in the southern part and gold-silver mineral occurrences are found in the northern part of the study area; identified low- to moderate-grade gold-silver resources occur adjacent to the study area along the western boundary. Six areas in the south-central and northwestern parts of the study area have high resource potential, two broad areas have moderate resource potential, and part of the southwest corner has low resource potential for lode gold, silver, and associated copper, lead, zinc, molybdenum, and tungsten. Alluvium locally within one of these areas has moderate resource potential for placer gold and silver, and the entire area has low resource potential for placer gold and silver. There is low resource potential for perlite, ornamental stone (onyx marble and opal), manganese, uranium and thorium, pegmatite minerals, and oil and gas within the study area. Sand and gravel are abundant but are readily available outside the wilderness study area.

Profiling of urinary bile acids in piglets by a combination of enzymatic deconjugation and targeted LC-MRM-MS[S

PubMed Central

Fang, Nianbai; Yu, Shanggong; Adams, Sean H.; Ronis, Martin J. J.; Badger, Thomas M.

2016-01-01

We present a method using a combination of enzymatic deconjugation and targeted LC-multiple reaction monitoring (MRM)-MS analysis for analyzing all common bile acids (BAs) in piglet urine, and in particular, for detecting conjugated BAs either in the absence of their standards, or when present in low concentrations. Initially, before enzymatic deconjugation, 19 unconjugated BAs (FBAs) were detected where the total concentration of the detected FBAs was 9.90 μmol/l. Sixty-seven conjugated BAs were identified by LC-MRM-MS analysis before and after enzymatic deconjugation. Four enzymatic assays were used to deconjugate the BA conjugates. FBAs in urine after cholylglycine hydrolase/sulfatase treatment were 33.40 μmol/l, indicating the urinary BAs were comprised of 29.75% FBAs and 70.25% conjugated BAs in single and multiple conjugated forms. For the conjugates in single form, released FBAs from cholylglycine hydrolase deconjugation indicated that the conjugates with amino acids were 14.54% of urinary BAs, 16.27% glycosidic conjugates were found by β-glucuronidase treatment, and sulfatase with glucuronidase inhibitor treatment liberated FBAs that constituted 16.67% of urinary BAs. Notably, chenodeoxycholic acid (CDCA) was initially detected only in trace amounts in urine, but was found at significant levels after the enzymatic assays above. These results support that CDCA is a precursor of γ-muricholic acid in BA biosynthesis in piglets. PMID:27538824

Serum bile acid level and fatty acid composition in Chinese children with non-alcoholic fatty liver disease.

PubMed

Lu, Li Ping; Wan, Yan Ping; Xun, Peng Cheng; Zhou, Ke Jun; Chen, Cheng; Cheng, Si Yang; Zhang, Min Zhong; Wu, Chun Hua; Lin, Wei Wei; Jiang, Ying; Feng, Hai Xia; Wang, Jia Lu; He, Ka; Cai, Wei

2017-08-01

To determine serum bile acid (BA) and fatty acid (FA) profiles in Chinese children with non-alcoholic fatty liver disease (NAFLD). A total 76 children aged 4-17 years were categorized into three groups according to the presence and absence of as well as the severity of NAFLD, that is, non-NAFLD (control), mild and moderate to severe NAFLD groups, respectively, based on their liver ultrasonography findings. Serum BA and FA profiles were quantified separately by mass spectrometry and gas chromatography. General linear models were performed to assess the differences among the groups. After adjusted for potential confounders, children with NAFLD had higher levels of chenodeoxycholic acid (CDCA), unconjugated primary BAs (CDCA + cholic acid) but lower levels of deoxycholic acid (DCA), taurodeoxycholic acid (TDCA), glycodeoxycholic acid (GDCA), total DCA (DCA + TDCA + GDCA), glycolithocholic acid (GLCA) and total lithocholic acid (GLCA + taurolithocholic acid) than children without NAFLD. As for FAs, children with mild and moderate to severe NAFLD had higher levels of n-7 monounsaturated FA. Circulating BA and FA profiles may change in children with NAFLD. Further studies are needed to determine their associations and to understand the underlying mechanism of action. © 2017 Chinese Medical Association Shanghai Branch, Chinese Society of Gastroenterology, Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine and John Wiley & Sons Australia, Ltd.

Profiling of urinary bile acids in piglets by a combination of enzymatic deconjugation and targeted LC-MRM-MS.

PubMed

Fang, Nianbai; Yu, Shanggong; Adams, Sean H; Ronis, Martin J J; Badger, Thomas M

2016-10-01

We present a method using a combination of enzymatic deconjugation and targeted LC-multiple reaction monitoring (MRM)-MS analysis for analyzing all common bile acids (BAs) in piglet urine, and in particular, for detecting conjugated BAs either in the absence of their standards, or when present in low concentrations. Initially, before enzymatic deconjugation, 19 unconjugated BAs (FBAs) were detected where the total concentration of the detected FBAs was 9.90 μmol/l. Sixty-seven conjugated BAs were identified by LC-MRM-MS analysis before and after enzymatic deconjugation. Four enzymatic assays were used to deconjugate the BA conjugates. FBAs in urine after cholylglycine hydrolase/sulfatase treatment were 33.40 μmol/l, indicating the urinary BAs were comprised of 29.75% FBAs and 70.25% conjugated BAs in single and multiple conjugated forms. For the conjugates in single form, released FBAs from cholylglycine hydrolase deconjugation indicated that the conjugates with amino acids were 14.54% of urinary BAs, 16.27% glycosidic conjugates were found by β-glucuronidase treatment, and sulfatase with glucuronidase inhibitor treatment liberated FBAs that constituted 16.67% of urinary BAs. Notably, chenodeoxycholic acid (CDCA) was initially detected only in trace amounts in urine, but was found at significant levels after the enzymatic assays above. These results support that CDCA is a precursor of γ-muricholic acid in BA biosynthesis in piglets. Copyright © 2016 by the American Society for Biochemistry and Molecular Biology, Inc.

Establishment of HLA-DR4 Transgenic Mice for the Identification of CD4+ T Cell Epitopes of Tumor-Associated Antigens

PubMed Central

Harada, Kumiko; Michibata, Yayoi; Tsukamoto, Hirotake; Senju, Satoru; Tomita, Yusuke; Yuno, Akira; Hirayama, Masatoshi; Abu Sayem, Mohammad; Takeda, Naoki; Shibuya, Isao; Sogo, Shinji; Fujiki, Fumihiro; Sugiyama, Haruo; Eto, Masatoshi; Nishimura, Yasuharu

2013-01-01

Reports have shown that activation of tumor-specific CD4+ helper T (Th) cells is crucial for effective anti-tumor immunity and identification of Th-cell epitopes is critical for peptide vaccine-based cancer immunotherapy. Although computer algorithms are available to predict peptides with high binding affinity to a specific HLA class II molecule, the ability of those peptides to induce Th-cell responses must be evaluated. We have established HLA-DR4 (HLA-DRA*01:01/HLA-DRB1*04:05) transgenic mice (Tgm), since this HLA-DR allele is most frequent (13.6%) in Japanese population, to evaluate HLA-DR4-restricted Th-cell responses to tumor-associated antigen (TAA)-derived peptides predicted to bind to HLA-DR4. To avoid weak binding between mouse CD4 and HLA-DR4, Tgm were designed to express chimeric HLA-DR4/I-Ed, where I-Ed α1 and β1 domains were replaced with those from HLA-DR4. Th cells isolated from Tgm immunized with adjuvant and HLA-DR4-binding cytomegalovirus-derived peptide proliferated when stimulated with peptide-pulsed HLA-DR4-transduced mouse L cells, indicating chimeric HLA-DR4/I-Ed has equivalent antigen presenting capacity to HLA-DR4. Immunization with CDCA155-78 peptide, a computer algorithm-predicted HLA-DR4-binding peptide derived from TAA CDCA1, successfully induced Th-cell responses in Tgm, while immunization of HLA-DR4-binding Wilms' tumor 1 antigen-derived peptide with identical amino acid sequence to mouse ortholog failed. This was overcome by using peptide-pulsed syngeneic bone marrow-derived dendritic cells (BM-DC) followed by immunization with peptide/CFA booster. BM-DC-based immunization of KIF20A494-517 peptide from another TAA KIF20A, with an almost identical HLA-binding core amino acid sequence to mouse ortholog, successfully induced Th-cell responses in Tgm. Notably, both CDCA155-78 and KIF20A494-517 peptides induced human Th-cell responses in PBMCs from HLA-DR4-positive donors. Finally, an HLA-DR4 binding DEPDC1191-213 peptide from a new TAA DEPDC1 overexpressed in bladder cancer induced strong Th-cell responses both in Tgm and in PBMCs from an HLA-DR4-positive donor. Thus, the HLA-DR4 Tgm combined with computer algorithm was useful for preliminary screening of candidate peptides for vaccination. PMID:24386437

Silicate Weathering and Carbon Cycle Controls on the Oligocene-Miocene Transition Glaciation

NASA Astrophysics Data System (ADS)

Stewart, Joseph A.; James, Rachael H.; Anand, Pallavi; Wilson, Paul A.

2017-10-01

Changes in both silicate weathering rates and organic carbon burial have been proposed as drivers of the transient "Mi-1" glaciation event at the Oligocene-Miocene transition (OMT; 23 Ma). However, detailed geochemical proxy data are required to test these hypotheses. Here we present records of Li/Ca, Mg/Ca, Cd/Ca, U/Ca, δ18O, δ13C, and shell weight in planktonic foraminifera from marine sediments spanning the OMT in the equatorial Atlantic Ocean. Li/Ca values increase by 1 μmol/mol across this interval. We interpret this to indicate an 20% increase in silicate weathering rates, which would have lowered atmospheric CO2, potentially forcing the Antarctic glaciation 23 Ma. δ13C of thermocline dwelling planktonic foraminifera track the global increase in seawater δ13C across the OMT and during the Mi-1 event, hence supporting a hypothesized global increase in organic carbon burial rates. High δ13C previously measured in epipelagic planktonic foraminifera and high Cd/Ca ratios during Mi-1 are interpreted to represent locally enhanced primary productivity, stimulated by increased nutrients supply to surface waters. The fingerprint of high export production and associated organic carbon burial at this site is found in reduced bottom water oxygenation (inferred from high foraminiferal U/Ca) and enhanced respiratory dissolution of carbonates, characterized by reduced foraminiferal shell weight. Replication of our results elsewhere would strengthen the case that weathering-induced CO2 sequestration preconditioned climate for Antarctic ice sheet growth across the OMT, and increased burial of organic carbon acted as a feedback that intensified cooling at this time.

A solid-phase extraction procedure coupled to 1H NMR, with chemometric analysis, to seek reliable markers of the botanical origin of honey.

PubMed

Beretta, Giangiacomo; Caneva, Enrico; Regazzoni, Luca; Bakhtyari, Nazanin Golbamaki; Maffei Facino, Roberto

2008-07-14

The aim of this work was to establish an analytical method for identifying the botanical origin of honey, as an alternative to conventional melissopalynological, organoleptic and instrumental methods (gas-chromatography coupled to mass spectrometry (GC-MS), high-performance liquid chromatography HPLC). The procedure is based on the (1)H nuclear magnetic resonance (NMR) profile coupled, when necessary, with electrospray ionisation-mass spectrometry (ESI-MS) and two-dimensional NMR analyses of solid-phase extraction (SPE)-purified honey samples, followed by chemometric analyses. Extracts of 44 commercial Italian honeys from 20 different botanical sources were analyzed. Honeydew, chestnut and linden honeys showed constant, specific, well-resolved resonances, suitable for use as markers of origin. Honeydew honey contained the typical resonances of an aliphatic component, very likely deriving from the plant phloem sap or excreted into it by sap-sucking aphids. Chestnut honey contained the typical signals of kynurenic acid and some structurally related metabolite. In linden honey the (1)H NMR profile gave strong signals attributable to the mono-terpene derivative cyclohexa-1,3-diene-1-carboxylic acid (CDCA) and to its 1-O-beta-gentiobiosyl ester (CDCA-GBE). These markers were not detectable in the other honeys, except for the less common nectar honey from rosa mosqueta. We compared and analyzed the data by multivariate techniques. Principal component analysis found different clusters of honeys based on the presence of these specific markers. The results, although obviously only preliminary, suggest that the (1)H NMR profile (with HPLC-MS analysis when necessary) can be used as a reference framework for identifying the botanical origin of honey.

Ursodeoxycholic acid attenuates colonic epithelial secretory function

PubMed Central

Kelly, Orlaith B; Mroz, Magdalena S; Ward, Joseph B J; Colliva, Carolina; Scharl, Michael; Pellicciari, Roberto; Gilmer, John F; Fallon, Padraic G; Hofmann, Alan F; Roda, Aldo; Murray, Frank E; Keely, Stephen J

2013-01-01

Dihydroxy bile acids, such as chenodeoxycholic acid (CDCA), are well known to promote colonic fluid and electrolyte secretion, thereby causing diarrhoea associated with bile acid malabsorption. However, CDCA is rapidly metabolised by colonic bacteria to ursodeoxycholic acid (UDCA), the effects of which on epithelial transport are poorly characterised. Here, we investigated the role of UDCA in the regulation of colonic epithelial secretion. Cl− secretion was measured across voltage-clamped monolayers of T84 cells and muscle-stripped sections of mouse or human colon. Cell surface biotinylation was used to assess abundance/surface expression of transport proteins. Acute (15 min) treatment of T84 cells with bilateral UDCA attenuated Cl− secretory responses to the Ca2+ and cAMP-dependent secretagogues carbachol (CCh) and forskolin (FSK) to 14.0 ± 3.8 and 40.2 ± 7.4% of controls, respectively (n= 18, P < 0.001). Investigation of the molecular targets involved revealed that UDCA acts by inhibiting Na+/K+-ATPase activity and basolateral K+ channel currents, without altering their cell surface expression. In contrast, intraperitoneal administration of UDCA (25 mg kg−1) to mice enhanced agonist-induced colonic secretory responses, an effect we hypothesised to be due to bacterial metabolism of UDCA to lithocholic acid (LCA). Accordingly, LCA (50–200 μm) enhanced agonist-induced secretory responses in vitro and a metabolically stable UDCA analogue, 6α-methyl-UDCA, exerted anti-secretory actions in vitro and in vivo. In conclusion, UDCA exerts direct anti-secretory actions on colonic epithelial cells and metabolically stable derivatives of the bile acid may offer a new approach for treating intestinal diseases associated with diarrhoea. PMID:23507881

Ursodeoxycholic acid inhibits overexpression of P-glycoprotein induced by doxorubicin in HepG2 cells.

PubMed

Komori, Yuki; Arisawa, Sakiko; Takai, Miho; Yokoyama, Kunihiro; Honda, Minako; Hayashi, Kazuhiko; Ishigami, Masatoshi; Katano, Yoshiaki; Goto, Hidemi; Ueyama, Jun; Ishikawa, Tetsuya; Wakusawa, Shinya

2014-02-05

The hepatoprotective action of ursodeoxycholic acid (UDCA) was previously suggested to be partially dependent on its antioxidative effect. Doxorubicin (DOX) and reactive oxygen species have also been implicated in the overexpression of P-glycoprotein (P-gp), which is encoded by the MDR1 gene and causes antitumor multidrug resistance. In the present study, we assessed the effects of UDCA on the expression of MDR1 mRNA, P-gp, and intracellular reactive oxygen species levels in DOX-treated HepG2 cells and compared them to those of other bile acids. DOX-induced increases in reactive oxygen species levels and the expression of MDR1 mRNA were inhibited by N-acetylcysteine, an antioxidant, and the DOX-induced increase in reactive oxygen species levels and DOX-induced overexpression of MDR1 mRNA and P-gp were inhibited by UDCA. Cells treated with UDCA showed improved rhodamine 123 uptake, which was decreased in cells treated with DOX alone. Moreover, cells exposed to DOX for 24h combined with UDCA accumulated more DOX than that of cells treated with DOX alone. Thus, UDCA may have inhibited the overexpression of P-gp by suppressing DOX-induced reactive oxygen species production. Chenodeoxycholic acid (CDCA) also exhibited these effects, whereas deoxycholic acid and litocholic acid were ineffective. In conclusion, UDCA and CDCA had an inhibitory effect on the induction of P-gp expression and reactive oxygen species by DOX in HepG2 cells. The administration of UDCA may be beneficial due to its ability to prevent the overexpression of reactive oxygen species and acquisition of multidrug resistance in hepatocellular carcinoma cells. Copyright © 2013 Elsevier B.V. All rights reserved.

Use of biocidal products (insect sprays and electro-vaporizer) in indoor areas--exposure scenarios and exposure modeling.

PubMed

Berger-Preiss, Edith; Koch, Wolfgang; Gerling, Susanne; Kock, Heiko; Appel, Klaus E

2009-09-01

Five commercially available insect sprays were applied in a model room. Spraying was performed in accordance with the manufacturers' instructions and in an overdosed manner in order to simulate worst-case conditions or an unforeseeable misuse. In addition, we examined electro-vaporizers. The Respicon aerosol monitoring system was applied to determine inhalation exposure. During normal spraying (10 seconds) and during the following 2-3 minutes, exposure concentrations ranged from 70 to 590 microg/m3 for the pyrethroids tetramethrin, d-phenothrin, cyfluthrin, bioallethrin, and the pyrethrins. Calculated inhalable doses were 2-16 microg. A concentration of approximately 850 microg chlorpyrifos/m(3) (inhalable dose: approximately 20 microg) was determined when the "Contra insect fly spray" was applied. Highest exposure concentrations (1100-2100 microg/m3) were measured for piperonyl butoxide (PBO), corresponding to an inhalation intake of 30-60microg. When simulating worst-case conditions, exposure concentrations of 200-3400microg/m3 and inhalable doses of 10-210microg were determined for the various active substances. Highest concentrations (4800-8000 microg/m3) were measured for PBO (inhalable: 290-480 microg). By applying the electro-vaporizer "Nexa Lotte" plug-in mosquito killer concentrations for d-allethrin were in the range of 5-12microg/m3 and 0.5-2 microg/m3 for PBO while with the "Paral" plug-in mosquito killer concentrations of 0.4-5microg/m3 for pyrethrins and 1-7 microg/m3 for PBO were measured. Potential dermal exposures were determined using exposure pads. Between 80 and 1000microg active substance (tetramethrin, phenothrin, cyfluthrin, bioallethrin, pyrethrins, chlorpyrifos) were deposited on the clothing of the total body surface area of the spray user. Highest levels (up to 3000 microg) were determined for PBO. Worst-case uses of the sprays led to 5-9 times higher concentrations. Also a 2-hour stay nearby an operating electro-vaporizer led to a contamination of the clothing (total amounts on the whole body were 450 microg d-allethrin and 50 microg PBO for "Nexa Lotte" plug-in mosquito killer and 80 microg pyrethrins and 190 microg PBO for "Paral" plug-in mosquito killer). Human biomonitoring data revealed urine concentrations of the metabolite (E)-trans-chrysanthemum dicarboxylic acid ((E)-trans-CDCA) between 1.7 microg/l and 7.1 microg/l after 5 minutes of exposure to the different sprays. Also the use of electro-vaporizers led to (E)-trans-CDCA concentrations in the urine in the range of 1.0 microg/l to 6.2 microg/l (1-3 hours exposure period). The exposure data presented can be used for performing human risk assessment when these biocidal products were applied indoors. The airborne concentrations of the non-volatile active chemical compounds could be predicted from first principles using a deterministic exposure model (SprayExpo).

Reconstruction of an Integrated Genome-Scale Co-Expression Network Reveals Key Modules Involved in Lung Adenocarcinoma

PubMed Central

Hosseini Ashtiani, Saman; Moeini, Ali; Nowzari-Dalini, Abbas; Masoudi-Nejad, Ali

2013-01-01

Our goal of this study was to reconstruct a “genome-scale co-expression network” and find important modules in lung adenocarcinoma so that we could identify the genes involved in lung adenocarcinoma. We integrated gene mutation, GWAS, CGH, array-CGH and SNP array data in order to identify important genes and loci in genome-scale. Afterwards, on the basis of the identified genes a co-expression network was reconstructed from the co-expression data. The reconstructed network was named “genome-scale co-expression network”. As the next step, 23 key modules were disclosed through clustering. In this study a number of genes have been identified for the first time to be implicated in lung adenocarcinoma by analyzing the modules. The genes EGFR, PIK3CA, TAF15, XIAP, VAPB, Appl1, Rab5a, ARF4, CLPTM1L, SP4, ZNF124, LPP, FOXP1, SOX18, MSX2, NFE2L2, SMARCC1, TRA2B, CBX3, PRPF6, ATP6V1C1, MYBBP1A, MACF1, GRM2, TBXA2R, PRKAR2A, PTK2, PGF and MYO10 are among the genes that belong to modules 1 and 22. All these genes, being implicated in at least one of the phenomena, namely cell survival, proliferation and metastasis, have an over-expression pattern similar to that of EGFR. In few modules, the genes such as CCNA2 (Cyclin A2), CCNB2 (Cyclin B2), CDK1, CDK5, CDC27, CDCA5, CDCA8, ASPM, BUB1, KIF15, KIF2C, NEK2, NUSAP1, PRC1, SMC4, SYCE2, TFDP1, CDC42 and ARHGEF9 are present that play a crucial role in cell cycle progression. In addition to the mentioned genes, there are some other genes (i.e. DLGAP5, BIRC5, PSMD2, Src, TTK, SENP2, PSMD2, DOK2, FUS and etc.) in the modules. PMID:23874428

Reconstruction of an integrated genome-scale co-expression network reveals key modules involved in lung adenocarcinoma.

PubMed

Bidkhori, Gholamreza; Narimani, Zahra; Hosseini Ashtiani, Saman; Moeini, Ali; Nowzari-Dalini, Abbas; Masoudi-Nejad, Ali

2013-01-01

Our goal of this study was to reconstruct a "genome-scale co-expression network" and find important modules in lung adenocarcinoma so that we could identify the genes involved in lung adenocarcinoma. We integrated gene mutation, GWAS, CGH, array-CGH and SNP array data in order to identify important genes and loci in genome-scale. Afterwards, on the basis of the identified genes a co-expression network was reconstructed from the co-expression data. The reconstructed network was named "genome-scale co-expression network". As the next step, 23 key modules were disclosed through clustering. In this study a number of genes have been identified for the first time to be implicated in lung adenocarcinoma by analyzing the modules. The genes EGFR, PIK3CA, TAF15, XIAP, VAPB, Appl1, Rab5a, ARF4, CLPTM1L, SP4, ZNF124, LPP, FOXP1, SOX18, MSX2, NFE2L2, SMARCC1, TRA2B, CBX3, PRPF6, ATP6V1C1, MYBBP1A, MACF1, GRM2, TBXA2R, PRKAR2A, PTK2, PGF and MYO10 are among the genes that belong to modules 1 and 22. All these genes, being implicated in at least one of the phenomena, namely cell survival, proliferation and metastasis, have an over-expression pattern similar to that of EGFR. In few modules, the genes such as CCNA2 (Cyclin A2), CCNB2 (Cyclin B2), CDK1, CDK5, CDC27, CDCA5, CDCA8, ASPM, BUB1, KIF15, KIF2C, NEK2, NUSAP1, PRC1, SMC4, SYCE2, TFDP1, CDC42 and ARHGEF9 are present that play a crucial role in cell cycle progression. In addition to the mentioned genes, there are some other genes (i.e. DLGAP5, BIRC5, PSMD2, Src, TTK, SENP2, PSMD2, DOK2, FUS and etc.) in the modules.

Comparison on Response and Dissolution Rates Between Ursodeoxycholic Acid Alone or in Combination With Chenodeoxycholic Acid for Gallstone Dissolution According to Stone Density on CT Scan: Strobe Compliant Observation Study.

PubMed

Lee, Jae Min; Hyun, Jong Jin; Choi, In Young; Yeom, Suk Keu; Kim, Seung Young; Jung, Sung Woo; Jung, Young Kul; Koo, Ja Seol; Yim, Hyung Joon; Lee, Hong Sik; Lee, Sang Woo; Kim, Chang Duck

2015-12-01

Medical dissolution of gallstone is usually performed on radiolucent gallstones in a functioning gallbladder. However, absence of visible gallstone on plain abdominal x-ray does not always preclude calcification. This study aims to compare the response and dissolution rates between ursodeoxycholic acid (UDCA) alone or in combination with chenodeoxycholic acid (CDCA) according to stone density on computed tomography (CT) scan. A total of 126 patients underwent dissolution therapy with either UDCA alone or combination of CDCA and UDCA (CNU) from December 2010 to March 2014 at Korea University Ansan Hospital. In the end, 81 patients (CNU group = 44, UDCA group = 37) completed dissolution therapy for 6 months. Dissolution rate (percentage reduction in the gallstone volume) and response to therapy (complete dissolution or partial dissolution defined as reduction in stone volume of >50%) were compared between the 2 groups. Dissolution and response rates of sludge was also compared between the 2 groups. The overall response rate was 50.6% (CNU group 43.2% vs UDCA group 59.5%, P = 0.14), and the overall dissolution rate was 48.34% (CNU group 41.5% vs UDCA group 56.5%, P = 0.13). When analyzed according to stone density, response rate was 33.3%, 87.1%, 30.0%, and 6.2% for hypodense, isodense, hyperdense, and calcified stones, respectively. Response rate (85.7% vs 88.2%, P = 0.83) and dissolution rate (81.01% vs 85.38%, P = 0.17) of isodense stones were similar between CNU and UDCA group. When only sludge was considered, the overall response rate was 87.5% (CNU group 71.4% vs UDCA group 94.1%, P = 0.19), and the overall dissolution rate was 85.42% (CNU group 67.9% vs UDCA group 92.7%, P = 0.23). Patients with isodense gallstones and sludge showed much better response to dissolution therapy with CNU and UDCA showing comparable efficacy. Therefore, CT scan should be performed before medication therapy if stone dissolution is intended.

Auction development for the price-based electric power industry

NASA Astrophysics Data System (ADS)

Dekrajangpetch, Somgiat

The restructuring of the electric power industry is to move away from the cost-based monopolistic environment of the past to the priced-based competitive environment. As the electric power industry is restructuring in many places, there are still many problems that need to be solved. The work in this dissertation contributes to solve some of the electric power auction problems. The majority of this work is aimed to help develop good markets. A LaGrangian relaxation (LR) Centralized Daily Commitment Auction (CDCA) has been implemented. It has been shown that the solution might not be optimal nor fair to some generation companies (GENCOs) when identical or similar generating units participate in a LR CDCA based auction. Supporting information for bidding strategies on how to change unit data to enhance the chances of bid acceptance has been developed. The majority of this work is based on Single Period Commodity Auction (SPCA). Alternative structures for the SPCA are outlined. Whether the optimal solution is degenerated is investigated. Good pricing criteria are summarized and the pricing method following good pricing criteria is developed. Electricity is generally considered as a homogeneous product. When availability level is used as additional characteristic to distinct electricity, electricity can be considered a heterogeneous product. The procedure to trade electricity as a heterogeneous product is developed. The SPCA is formulated as a linear program. The basic IPLP algorithm has been extended so that sensitivity analysis can be performed as in the simplex method. Sensitivity analysis is used to determine market reach. Additionally, sensitivity analysis is used in combination with the investigation of historical auction results to provide raw data for power system expansion. Market power is a critical issue in electric power deregulation. Firms with market power have an advantage over other competitor firms in terms of market reach. Various approaches to determine market power and market reach are to be investigated. How firms can acquire additional customers or additional transactions, given the auction results, is to be investigated. Additionally, how firms can utilize their market power to enhance their chances of success is to be investigated.

Mineral resources of the Whipple Mountains and Whipple Mountains Addition Wilderness Study Areas, San Bernardino County, California

USGS Publications Warehouse

Marsh, Sherman P.; Raines, Gary L.; Diggles, Michael F.; Howard, Keith A.; Simpson, Robert W.; Hoover, Donald B.; Ridenour, James; Moyle, Phillip R.; Willett, Spencee L.

1988-01-01

At the request of the U.S. Bureau of Land Management, approximately 85,100 acres of the Whipple Mountains Wilderness Study Area (CDCA-312) and 1,380 acres of the Whipple Mountains Addition Wilderness Study Area (AZ-050-010) were evaluated for identified mineral resources (known) and mineral resource potential (undiscovered). In this report, the Whipple Mountains and Whipple Mountains Addition Wilderness Study Areas are referred to as simply "the study area." Most of the mines and prospects with identified resources in the Whipple Mountains Wilderness Study Area are within areas designated as having mineral resource potential. The area in and around the Turk Silver mine and the Lucky Green group and the area near the northwest boundary of the study area have high mineral resource potential for copper, lead, zinc, gold, and silver. An area along the west boundary of the study area has moderate resource potential for copper lead, zinc, gold, and silver. An area in the east adjacent to the Whipple Mountains Addition Wilderness Study Area has moderate resource potential for copper, gold, and silver resources. One area on the north boundary and one on the southeast boundary of the study area have low mineral resource potential for copper, lead, zinc, gold, and silver. Two areas, one on the north boundary and one inside the east boundary of the study area, have moderate resource potential for manganese. A small area inside the south boundary of the study area has high resource potential for decorative building stone, and the entire study area has low resource potential for sand and gravel and other rock products suitable for construction. Two areas in the eastern part of the study area have low resource potential for uranium. There is no resource potential for oil and gas or geothermal resources in the Whipple Mountains Wilderness Study Area. Sites within the Whipple Mountains Wilderness Study Area with identified resources of copper, gold, silver, manganese and (or) decorative building stone are located at the Stewart mine, New American Eagle mine, Turk Silver mine, Twin Lode mine, decorative stone property, Lucky Green group, Blue Cloud mine, Nickel Plate mine, Crescent mine, Quadrangle Copper group, and the Copper Basin mine. The Whipple Mountains Addition Wilderness Study Area has moderate resource potential for copper, gold, and silver resources and low resource potential for sand and gravel and other rock products. There is no resource potential for oil and gas or for geothermal energy in the Whipple Mountains Addition Wilderness Study Area. Although there are no identified resources in the Whipple Mountains Addition Wilderness Study Area, sites within and immediately adjacent warrant further study because of gold assays from widespread, numerous samples.

The geochemistry of redox sensitive trace metals in sediments

NASA Astrophysics Data System (ADS)

Morford, Jennifer L.; Emerson, Steven

1999-06-01

We analyzed the redox sensitive elements V, Mo, U, Re and Cd in surface sediments from the Northwest African margin, the U.S. Northwest margin and the Arabian Sea to determine their response under a range of redox conditions. Where oxygen penetrates 1 cm or less into the sediments, Mo and V diffuse to the overlying water as Mn is reduced and remobilized. Authigenic enrichments of U, Re and Cd are evident under these redox conditions. With the onset of sulfate reduction, all of the metals accumulate authigenically with Re being by far the most enriched. General trends in authigenic metal accumulation are described by calculating authigenic fluxes for the 3 main redox regimes: oxic, reducing where oxygen penetrates ≤1 cm, and anoxic conditions. Using a simple diagenesis model and global estimates of organic carbon rain rate and bottom water oxygen concentrations, we calculate the area of sediments below 1000 m water depth in which oxygen penetration is ≤1 cm to be 4% of the ocean floor. We conclude that sediments where oxygen penetrates ≤1 cm release Mn, V and Mo to seawater at rates of 140%-260%, 60%-150% and 5%-10% of their respective riverine fluxes, using the authigenic metal concentrations and accumulation rates from this work and other literature. These sediments are sinks for Re, Cd and U, with burial fluxes of 70%-140%, 30%-80% and 20%-40%, respectively, of their dissolved riverine inputs. We modeled the sensitivity of the response of seawater Re, Cd and V concentrations to changes in the area of reducing sediments where oxygen penetrates ≤1 cm. Our analysis suggests a negligible change in seawater Re concentration, whereas seawater concentrations of Cd and V could have decreased and increased, respectively, by 5%-10% over 20 kyr if the area of reducing sediments increased by a factor of 2 and by 10%-20% if the area increased by a factor of 3. The concentration variations for a factor of 2 increase in the area of reducing sediments are at about the level of uncertainty of Cd/Ca and V/Ca ratios observed in foraminifera shells over the last 40 kyr. This implies that the area of reducing sediments in the ocean deeper than 1000 m (4%) has not been greater than twice the present value in the recent past.

The impact of human activities on sediments of San Francisco Bay, California: an overview

USGS Publications Warehouse

van Geen, Alexander; Luoma, Samuel N.

1999-01-01

This note introduces a set of eight papers devoted to a detailed study of two sediment cores from San Francisco Bay with an overview of the region and a chronology of human activities. Data used in this study to constrain the range of sediment ages at different depths include , and  concentrations in the sediment and the  age of shell fragments. In order of first detectable appearance in the record, the indicators of contamination that were analyzed include PAHs>Hg>Ag, Cu, Pb, Zn>DDT, PCB>foraminiferal Cd/Ca. This study also documents a large memory effect for estuarine contamination caused by sediment mixing and resuspension. Once an estuary such as San Francisco Bay has been contaminated, decades must pass before contaminant levels in surface sediment will return to background levels, even if external contaminant inputs have been entirely eliminated.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Das, Amitabh, E-mail: amitabhdas.kn@gmail.com; Chai, Jin Choul, E-mail: jincchai@gmail.com; Jung, Kyoung Hwa, E-mail: khjung2@gmail.com

JMJD2A is a lysine trimethyl-specific histone demethylase that is highly expressed in a variety of tumours. The role of JMJD2A in tumour progression remains unclear. The objectives of this study were to identify JMJD2A-regulated genes and understand the function of JMJD2A in p53-null neuroectodermal stem cells (p53{sup −/−} NE-4Cs). We determined the effect of LPS as a model of inflammation in p53{sup −/−} NE-4Cs and investigated whether the epigenetic modifier JMJD2A alter the expression of tumourigenic inflammatory genes. Global gene expression was measured in JMJD2A knockdown (kd) p53{sup −/−} NE-4Cs and in LPS-stimulated JMJD2A-kd p53{sup −/−} NE-4C cells. JMJD2A attenuationmore » significantly down-regulated genes were Cdca2, Ccnd2, Ccnd1, Crebbp, IL6rα, and Stat3 related with cell cycle, proliferation, and inflammatory-disease responses. Importantly, some tumour-suppressor genes including Dapk3, Timp2 and TFPI were significantly up-regulated but were not affected by silencing of the JMJD2B. Furthermore, we confirmed the attenuation of JMJD2A also down-regulated Cdca2, Ccnd2, Crebbp, and Rest in primary NSCs isolated from the forebrains of E15 embryos of C57/BL6J mice with effective p53 inhibitor pifithrin-α (PFT-α). Transcription factor (TF) motif analysis revealed known binding patterns for CDC5, MYC, and CREB, as well as three novel motifs in JMJD2A-regulated genes. IPA established molecular networks. The molecular network signatures and functional gene-expression profiling data from this study warrants further investigation as an effective therapeutic target, and studies to elucidate the molecular mechanism of JMJD2A-kd-dependent effects in neuroectodermal stem cells should be performed. - Highlights: • Significant up-regulation of epigenetic modifier JMJD2A mRNA upon LPS treatment. • Inhibition of JMJD2A attenuated key inflammatory and tumourigenic genes. • Establishing IPA based functional genomics in JMJD2A-attenuated p53{sup −/−} NE4C cells. • Finding JMJD2A-based molecular targets and crucial pathways in p53{sup −/−} NE4C cells.« less

Influences of different land use spatial control schemes on farmland conversion and urban development.

PubMed

Zhou, Min; Tan, Shukui; Zhang, Lu

2015-01-01

Land use planning is always officially implemented as an effective tool to control urban development and protect farmland. However, its impact on land use change remains untested in China. Using a case study of Hang-Jia-Hu region, the main objective of this paper was to investigate the influence of different land use spatial control schemes on farmland conversion and urban development. Comparisons of farmland conversion and urban development patterns between the urban planning area and the non-urban planning area were characterized by using remote sensing, geographical information systems, and landscape metrics. Results indicated that farmland conversion in the non-urban planning area was more intensive than that in the urban planning area, and that farmland patterns was more fragmented in the non-urban planning area. Built-up land patterns in the non-urban planning area showed a trend of aggregation, while those in the urban planning area had a dual trend of fragmentation and aggregation. Existing built-up areas had less influence on built-up land sprawl in the non-urban planning area than that in the urban planning area. Built-up land sprawl in the form of continuous development in the urban planning area led to farmland conversion; and in the non-urban planning area, built-up land sprawl in the form of leapfrogging development resulted in farmland areal declines and fragmentation. We argued that it is a basic requirement to integrate land use plans in urban and non-urban planning areas for land use planning and management.

Influences of Different Land Use Spatial Control Schemes on Farmland Conversion and Urban Development

PubMed Central

Zhou, Min; Tan, Shukui; Zhang, Lu

2015-01-01

Land use planning is always officially implemented as an effective tool to control urban development and protect farmland. However, its impact on land use change remains untested in China. Using a case study of Hang-Jia-Hu region, the main objective of this paper was to investigate the influence of different land use spatial control schemes on farmland conversion and urban development. Comparisons of farmland conversion and urban development patterns between the urban planning area and the non-urban planning area were characterized by using remote sensing, geographical information systems, and landscape metrics. Results indicated that farmland conversion in the non-urban planning area was more intensive than that in the urban planning area, and that farmland patterns was more fragmented in the non-urban planning area. Built-up land patterns in the non-urban planning area showed a trend of aggregation, while those in the urban planning area had a dual trend of fragmentation and aggregation. Existing built-up areas had less influence on built-up land sprawl in the non-urban planning area than that in the urban planning area. Built-up land sprawl in the form of continuous development in the urban planning area led to farmland conversion; and in the non-urban planning area, built-up land sprawl in the form of leapfrogging development resulted in farmland areal declines and fragmentation. We argued that it is a basic requirement to integrate land use plans in urban and non-urban planning areas for land use planning and management. PMID:25915897

33 CFR 103.510 - Area Maritime Security (AMS) Plan review and approval.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Area Maritime Security (AMS) Plan... HOMELAND SECURITY MARITIME SECURITY MARITIME SECURITY: AREA MARITIME SECURITY Area Maritime Security (AMS) Plan § 103.510 Area Maritime Security (AMS) Plan review and approval. Each AMS Plan will be submitted...

Induction of long-lived room temperature phosphorescence of carbon dots by water in hydrogen-bonded matrices.

PubMed

Li, Qijun; Zhou, Ming; Yang, Mingyang; Yang, Qingfeng; Zhang, Zhixun; Shi, Jing

2018-02-21

Phosphorescence shows great potential for application in bioimaging and ion detection because of its long-lived luminescence and high signal-to-noise ratio, but establishing phosphorescence emission in aqueous environments remains a challenge. Herein, we present a general design strategy that effectively promotes phosphorescence by utilising water molecules to construct hydrogen-bonded networks between carbon dots (CDs) and cyanuric acid (CA). Interestingly, water molecules not only cause no phosphorescence quenching but also greatly enhance the phosphorescence emission. This enhancement behaviour can be explained by the fact that the highly ordered bound water on the CA particle surface can construct robust bridge-like hydrogen-bonded networks between the CDs and CA, which not only effectively rigidifies the C=O bonds of the CDs but also greatly enhances the rigidity of the entire system. In addition, the CD-CA suspension exhibits a high phosphorescence lifetime (687 ms) and is successfully applied in ion detection based on its visible phosphorescence.

JPO2/CDCA7L and LEDGF/p75 Are Novel Mediators of PI3K/AKT Signaling and Aggressive Phenotypes in Medulloblastoma.

PubMed

Chan, Tiffany Sin Yu; Hawkins, Cynthia; Krieger, Jonathan R; McGlade, C Jane; Huang, Annie

2016-05-01

Substantial evidence links Myc-PI3K/AKT signaling to the most aggressive subtype of medulloblastoma and this axis in medulloblastoma therapy. In this study, we advance understanding of how Myc-PI3K/AKT signaling contributes to this malignancy, specifically, in identifying the Myc-interacting protein JPO2 and its partner binding protein LEDGF/p75 as critical modulators of PI3K/AKT signaling and metastasis in medulloblastoma. JPO2 overexpression induced metastatic medulloblastoma in vivo through two synergistic feed-forward regulatory circuits involving LEDGF/p75 and AKT that promote metastatic phenotypes in this setting. Overall, our findings highlight two novel prometastatic loci in medulloblastoma and point to the JPO2:LEDGF/p75 protein complex as a potentially new targetable component of PI3K/AKT signaling in medulloblastoma. Cancer Res; 76(9); 2802-12. ©2016 AACR. ©2016 American Association for Cancer Research.

Role of metal mixtures (Ca, Cu and Pb) on Cd bioaccumulation and phytochelatin production by Chlamydomonas reinhardtii.

PubMed

Abboud, Pauline; Wilkinson, Kevin J

2013-08-01

The goal of the study was to determine whether metal uptake and biological effects could be predicted by free ion concentrations when organisms were exposed to Cd and a second metal. Bioaccumulation and algal phytochelatin (PC) concentrations were determined for Chlamydomonas reinhardtii following a 6-h exposure. Bioaccumulation results, after six hours of exposure, showed that Cd uptake decreased in the presence of relatively high concentrations of Ca, Cu and Pb, however, Cd bioaccumulation increased in the presence of ca. equimolar concentrations of Cu. A good correlation was observed between the production of PCs and the amount of metals bioaccumulated for the binary mixtures of Cd-Pb and Cd-Cu, but not the Cd-Ca mixture. Overall, the results suggested that, in the case of mixtures, bioaccumulated metal rather than free ion concentrations would be a better predictor of biological effect. Copyright © 2013 Elsevier Ltd. All rights reserved.

Ursodeoxycholic acid increases low-density lipoprotein binding, uptake and degradation in isolated hamster hepatocytes.

PubMed Central

Bouscarel, B; Fromm, H; Ceryak, S; Cassidy, M M

1991-01-01

Ursodeoxycholic acid (UDCA), in contrast to both chenodeoxycholic acid (CDCA), its 7 alpha-epimer, and lithocholic acid, enhanced receptor-dependent low-density lipoprotein (LDL) uptake and degradation in isolated hamster hepatocytes. The increase in cell-associated LDL was time- and concentration-dependent, with a maximum effect observed at approx. 60 min with 1 mM-UDCA. This increase was not associated with a detergent effect of UDCA, as no significant modifications were observed either in the cellular release of lactate dehydrogenase or in Trypan Blue exclusion. The effect of UDCA was not due to a modification of the LDL particle, but rather was receptor-related. UDCA (1 mM) maximally increased the number of 125I-LDL-binding sites (Bmax.) by 35%, from 176 to 240 ng/mg of protein, without a significant modification of the binding affinity. Furthermore, following proteolytic degradation of the LDL receptor with Pronase, specific LDL binding decreased to the level of non-specific binding, and the effect of UDCA was abolished. Conversely, the trihydroxy 7 beta-hydroxy bile acid ursocholic acid and its 7 alpha-epimer, cholic acid, induced a significant decrease in LDL binding by approx. 15%. The C23 analogue of UDCA (nor-UDCA) and CDCA did not affect LDL binding. On the other hand, UDCA conjugated with either glycine (GUDCA) or taurine (TUDCA), increased LDL binding to the same extent as did the free bile acid. The half maximum time (t1/2) to reach the full effect was 1-2 min for UDCA and TUDCA, while GUDCA had a much slower t1/2 of 8.3 min. Ketoconazole (50 microM), an antifungal agent, increased LDL binding, but this effect was not additive when tested in the presence of 0.7 mM-UDCA. The results of the studies indicate that, in isolated hamster hepatocytes, the UDCA-induced increase in receptor-dependent LDL binding and uptake represents a direct effect of this bile acid. The action of the bile acid is closely related to its specific structural conformation, since UDCA and its conjugates are the only bile acids shown to express this ability thus far. However, certain agents other than bile acids, such as ketoconazole, have a similar effect. Finally, the studies suggest that the recruitment of LDL receptors from a latent pool in the hepatocellular membrane may be the mechanism by which UDCA exerts its direct effect. Images Fig. 6. PMID:1764022

Allspice and Clove As Source of Triterpene Acids Activating the G Protein-Coupled Bile Acid Receptor TGR5

PubMed Central

Ladurner, Angela; Zehl, Martin; Grienke, Ulrike; Hofstadler, Christoph; Faur, Nadina; Pereira, Fátima C.; Berry, David; Dirsch, Verena M.; Rollinger, Judith M.

2017-01-01

Worldwide, metabolic diseases such as obesity and type 2 diabetes have reached epidemic proportions. A major regulator of metabolic processes that gained interest in recent years is the bile acid receptor TGR5 (Takeda G protein-coupled receptor 5). This G protein-coupled membrane receptor can be found predominantly in the intestine, where it is mainly responsible for the secretion of the incretins glucagon-like peptide 1 (GLP-1) and peptide YY (PYY). The aim of this study was (i) to identify plant extracts with TGR5-activating potential, (ii) to narrow down their activity to the responsible constituents, and (iii) to assess whether the intestinal microbiota produces transformed metabolites with a different activity profile. Chenodeoxycholic acid (CDCA) served as positive control for both, the applied cell-based luciferase reporter gene assay for TGR5 activity and the biotransformation assay using mouse fecal slurry. The suitability of the workflow was demonstrated by the biotransformation of CDCA to lithocholic acid resulting in a distinct increase in TGR5 activity. Based on a traditional Tibetan formula, 19 plant extracts were selected and investigated for TGR5 activation. Extracts from the commonly used spices Syzygium aromaticum (SaroE, clove), Pimenta dioica (PdioE, allspice), and Kaempferia galanga (KgalE, aromatic ginger) significantly increased TGR5 activity. After biotransformation, only KgalE showed significant differences in its metabolite profile, which, however, did not alter its TGR5 activity compared to non-transformed KgalE. UHPLC-HRMS (high-resolution mass spectrometry) analysis revealed triterpene acids (TTAs) as the main constituents of the extracts SaroE and PdioE. Identification and quantification of TTAs in these two extracts as well as comparison of their TGR5 activity with reconstituted TTA mixtures allowed the attribution of the TGR5 activity to TTAs. EC50s were determined for the main TTAs, i.e., oleanolic acid (2.2 ± 1.6 μM), ursolic acid (1.1 ± 0.2 μM), as well as for the hitherto unknown TGR5 activators corosolic acid (0.5 ± 1.0 μM) and maslinic acid (3.7 ± 0.7 μM). In conclusion, extracts of clove, allspice, and aromatic ginger activate TGR5, which might play a pivotal role in their therapeutic use for the treatment of metabolic diseases. Moreover, the TGR5 activation of SaroE and PdioE could be pinpointed solely to TTAs. PMID:28769799

Areas of Indian Country Covered by the EPA Plan

EPA Pesticide Factsheets

Areas of Indian country covered by the EPA Plan for certification are those that are not covered by another EPA-approved certification plan.Most areas are NOT covered by an EPA-approved plan, so this new plan would apply to most locations.

78 FR 63481 - Therapeutic Area Standards Initiative Project Plan; Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-24

...] Therapeutic Area Standards Initiative Project Plan; Availability AGENCY: Food and Drug Administration, HHS... Therapeutic Area Standards Initiative Project Plan. This therapeutic area (TA) Project Plan will be the primary document for guiding all major aspects of FDA's multi-year initiative to develop and implement TA...

40 CFR 52.123 - Approval status.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Urban Planning Area for O3. (e) The Administrator finds that the plan does not satisfy all the... pollutants listed in this paragraph. (1) Maricopa County Urban Planning Area for CO and TSP. (2) [Reserved... TSP, the portion of the Tucson TSP Air Planning Area falling both within the area described by...

40 CFR 52.123 - Approval status.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Urban Planning Area for O3. (e) The Administrator finds that the plan does not satisfy all the... pollutants listed in this paragraph. (1) Maricopa County Urban Planning Area for CO and TSP. (2) [Reserved... TSP, the portion of the Tucson TSP Air Planning Area falling both within the area described by...

Montana rest area plan

DOT National Transportation Integrated Search

1999-12-01

Montana first developed a rest area plan in 1985; however, that plan no longer adequately sported decisions related to longe-range policy issues. Hence this docment represents a comprehensive effort to update rest area planning for Montana. A three p...

76 FR 33341 - Notice of Intent to prepare a Resource Management Plan for the West Eugene Wetlands Planning Area...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-08

....HAG11-0203] Notice of Intent to prepare a Resource Management Plan for the West Eugene Wetlands Planning... Planning Area and by this notice is announcing the beginning of the scoping process to solicit public comments and identify issues. The West Eugene Wetlands Planning Area comprises approximately 1,340 acres of...

7 CFR 275.18 - Project area/management unit corrective action plan.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 4 2010-01-01 2010-01-01 false Project area/management unit corrective action plan... SYSTEM Corrective Action § 275.18 Project area/management unit corrective action plan. (a) The State agency shall ensure that corrective action plans are prepared at the project area/management unit level...

7 CFR 275.18 - Project area/management unit corrective action plan.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 4 2013-01-01 2013-01-01 false Project area/management unit corrective action plan... SYSTEM Corrective Action § 275.18 Project area/management unit corrective action plan. (a) The State agency shall ensure that corrective action plans are prepared at the project area/management unit level...

7 CFR 275.18 - Project area/management unit corrective action plan.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 4 2014-01-01 2014-01-01 false Project area/management unit corrective action plan... SYSTEM Corrective Action § 275.18 Project area/management unit corrective action plan. (a) The State agency shall ensure that corrective action plans are prepared at the project area/management unit level...

7 CFR 275.18 - Project area/management unit corrective action plan.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 4 2011-01-01 2011-01-01 false Project area/management unit corrective action plan... SYSTEM Corrective Action § 275.18 Project area/management unit corrective action plan. (a) The State agency shall ensure that corrective action plans are prepared at the project area/management unit level...

7 CFR 275.18 - Project area/management unit corrective action plan.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 4 2012-01-01 2012-01-01 false Project area/management unit corrective action plan... SYSTEM Corrective Action § 275.18 Project area/management unit corrective action plan. (a) The State agency shall ensure that corrective action plans are prepared at the project area/management unit level...

Evaluation of the ADOT small area transportation studies and planning assistance for rural areas programs.

DOT National Transportation Integrated Search

2014-03-01

The Planning Assistance for Rural Areas (PARA) program, sponsored by the Arizona Department of Transportations : (ADOT) Multimodal Planning Division (MPD), dedicates funding and staff to conduct multimodal transportation planning : studies for loc...

75 FR 63139 - Approval and Promulgation of Implementation Plans-Maricopa County (Phoenix) PM-10 Nonattainment...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-14

... Promulgation of Implementation Plans--Maricopa County (Phoenix) PM-10 Nonattainment Area; Serious Area Plan for... implementation plan (SIP) revisions submitted by the State of Arizona to meet, among other requirements, section... (Maricopa area). Specifically, EPA proposed to disapprove provisions of the 189(d) plan because they do not...

18 CFR 141.51 - FERC Form No. 714, Annual Electric Balancing Authority Area and Planning Area Report.

Code of Federal Regulations, 2011 CFR

2011-04-01

..., Annual Electric Balancing Authority Area and Planning Area Report. 141.51 Section 141.51 Conservation of...) § 141.51 FERC Form No. 714, Annual Electric Balancing Authority Area and Planning Area Report. (a) Who... Policies Act, 16 U.S.C. 2602, operating a balancing authority area, and any group of electric utilities...

18 CFR 141.51 - FERC Form No. 714, Annual Electric Balancing Authority Area and Planning Area Report.

Code of Federal Regulations, 2013 CFR

2013-04-01

..., Annual Electric Balancing Authority Area and Planning Area Report. 141.51 Section 141.51 Conservation of...) § 141.51 FERC Form No. 714, Annual Electric Balancing Authority Area and Planning Area Report. (a) Who... Policies Act, 16 U.S.C. 2602, operating a balancing authority area, and any group of electric utilities...

18 CFR 141.51 - FERC Form No. 714, Annual Electric Balancing Authority Area and Planning Area Report.

Code of Federal Regulations, 2012 CFR

2012-04-01

..., Annual Electric Balancing Authority Area and Planning Area Report. 141.51 Section 141.51 Conservation of...) § 141.51 FERC Form No. 714, Annual Electric Balancing Authority Area and Planning Area Report. (a) Who... Policies Act, 16 U.S.C. 2602, operating a balancing authority area, and any group of electric utilities...

18 CFR 141.51 - FERC Form No. 714, Annual Electric Balancing Authority Area and Planning Area Report.

Code of Federal Regulations, 2010 CFR

2010-04-01

..., Annual Electric Balancing Authority Area and Planning Area Report. 141.51 Section 141.51 Conservation of...) § 141.51 FERC Form No. 714, Annual Electric Balancing Authority Area and Planning Area Report. (a) Who... Policies Act, 16 U.S.C. 2602, operating a balancing authority area, and any group of electric utilities...

18 CFR 141.51 - FERC Form No. 714, Annual Electric Balancing Authority Area and Planning Area Report.

Code of Federal Regulations, 2014 CFR

2014-04-01

..., Annual Electric Balancing Authority Area and Planning Area Report. 141.51 Section 141.51 Conservation of...) § 141.51 FERC Form No. 714, Annual Electric Balancing Authority Area and Planning Area Report. (a) Who... Policies Act, 16 U.S.C. 2602, operating a balancing authority area, and any group of electric utilities...

33 CFR 103.510 - Area Maritime Security (AMS) Plan review and approval.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Area Maritime Security (AMS) Plan review and approval. 103.510 Section 103.510 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF...) Plan § 103.510 Area Maritime Security (AMS) Plan review and approval. Each AMS Plan will be submitted...

77 FR 74508 - Notice of Availability of the Draft Resource Management Plan Amendment, Draft Environmental...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-14

... Statement for the Ring of Fire Resource Management Plan--Haines Planning Area, Alaska AGENCY: Bureau of Land.../Draft Environmental Impact Statement (EIS) for the Ring of Fire RMP for the Haines Planning Area and by... Fire RMP-- Haines Planning Area Amendment by any of the following methods: Email: [email protected

75 FR 17950 - Notice of Intent To Prepare Amendments to the Southeastern Oregon Resource Management Plan (RMP...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-08

... Office, 100 Oregon St., Vale, Oregon 97918. You may submit comments on issues and planning criteria... the Southeastern Oregon and Lakeview planning areas. The two planning areas are located in Malheur... in the Southeastern Oregon planning area and approximately 3.2 million acres of public land in the...

Wilderness fire management planning guide

Treesearch

William C. Fischer

1984-01-01

Outlines a procedure for fire management planning for parks; wilderness areas; and other wild, natural, or essentially undeveloped areas. Discusses background and philosophy of wilderness fire management, planning concepts, planning elements, and planning methods.

Area Community College and Area Vocational School Construction.

ERIC Educational Resources Information Center

Iowa State Dept. of Public Instruction, Des Moines.

The purpose of this guideline is to assist in the planning process, to encourage good school plant design, and to serve as criteria in the evaluation of area community college and area vocational school plans. It is divided into the following five sections--(1) area plant planning, (2) area sites, (3) physical facilities, (4) service systems, and…

Strategic planning in Brazilian protected areas: Uses and adjustments.

PubMed

Barreto, Cristiane Gomes; Drummond, José Augusto L

2017-09-15

Management plans for protected areas commonly use strategic planning tools in their drafting. It is proposed that the adequate use of the instruments of planning and management of protected areas can improve their strategic competitiveness, providing greater financial and administrative independence, enabling them to be economically sustainable organizations. This study evaluated the application of concepts and strategy formulation, strategy principles and competitiveness, organizational diagnosis, strategic maps, scenarios, and other strategic planning instruments used for conservation management in Brazil. 25 management plans of 25 different protected areas were selected and studied, with special attention to the indicators used in each plan. Results indicate that there is a high suitability for the application of SP tools to the universe of protected areas, although management plans did not take full advantage of these tools. We also found that the broader use of these tools did not guarantee greater managerial effectiveness. We suggest that other governance variables beyond planning strategies must be improved, to ensure a better performance of protected areas. Copyright © 2017 Elsevier Ltd. All rights reserved.

More choice in health insurance marketplaces may reduce the value of the subsidies available to low-income enrollees.

PubMed

Taylor, Erin A; Saltzman, Evan; Bauhoff, Sebastian; Pacula, Rosalie L; Eibner, Christine

2015-01-01

Federal subsidies available to enrollees in health insurance Marketplaces are pegged to the premium of the second-lowest-cost silver plan available in each rating area (as defined by each state). People who qualify for the subsidy contribute a percentage of their income to purchase coverage, and the federal government covers the remaining cost up to the price of that premium. Because the number of plans offered and plan premiums vary substantially across rating areas, the effective value of the subsidy may vary geographically. We found that the availability of more plans in a rating area was associated with lower premiums but higher deductibles for enrollees in the second-lowest-cost silver plan. In rating areas with more than twenty plans, the average deductible in the second-lowest-cost silver plan was nearly $1,000 higher than it was in rating areas with fewer than thirteen plans. Because premium costs for second-lowest-cost silver plans are capped, deductibles may be a more salient measure of plan value for enrollees than premiums are. Greater standardization of plans or an alternative approach to calculating the subsidy could provide a more consistent benefit to enrollees across various rating areas. Project HOPE—The People-to-People Health Foundation, Inc.

7 CFR 4284.630 - Other considerations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 1940 of this title. Applications for technical assistance or planning projects are generally excluded... within their plans the important environmental factors within the planning area and the potential environmental impacts of the plan on the planning area, as well as the alternative planning strategies that were...

A study on the use of near-infrared spectroscopy for the rapid quantification of major compounds in Tanreqing injection

NASA Astrophysics Data System (ADS)

Li, Wenlong; Cheng, Zhiwei; Wang, Yuefei; Qu, Haibin

2013-01-01

In this paper we describe the strategy used in the development and validation of a near infrared spectroscopy method for the rapid determination of baicalin, chlorogenic acid, ursodeoxycholic acid (UDCA), chenodeoxycholic acid (CDCA), and the total solid contents (TSCs) in the Tanreqing injection. To increase the representativeness of calibration sample set, a concentrating-diluting method was adopted to artificially prepare samples. Partial least square regression (PLSR) was used to establish calibration models, with which the five quality indicators can be determined with satisfied accuracy and repeatability. In addition, the slope/bias (S/B) method was used for the models transfer between two different types of NIR instruments from the same manufacturer, which is contributing to enlarge the application range of the established models. With the presented method, a great deal of time, effort and money can be saved when large amounts of Tanreqing injection samples need to be analyzed in a relatively short period of time, which is of great significance to the traditional Chinese medicine (TCM) industries.

Further evidence for a link between Late Pleistocene North Atlantic surface temperatures and North Atlantic deep-water production

NASA Astrophysics Data System (ADS)

Boyle, Edward A.; Rosener, Paula

1990-10-01

Reduced surface temperatures, salinity and North Atlantic Deep-Water (NADW) formation rate may be mechanistically linked. Previous studies have demonstrated the co-occurrence of lowered high-latitude T and NADW during glacial maxima and the brief ( t 1000 yr) Younger Dryas cooling event 10,500 years ago. This behavior also appears as a feature of a recent coupled ocean/atmosphere general circulation model. Here, it is shown that rapid fluctuations in North Atlantic surface temperatures (as indicated by variations from 7 to 22% left-cooling N. pachyderma) during oxygen isotope stage 3 also may be linked to fluctuations in deep-water chemistry (as indicated by benthic Cd/Ca variations from 0.080 to 0.120 μmol. mol. -1). Two complete cycles in both properties are observed in 30 cm of sediment; bioturbation modeling suggests that the true extrema are muted and that the reproducibility of replicate analyses is primarily limited by the sampling statistics of bioturbated mixrure. The current evidence raises the question of whether NADW is regulated by a "switch" or by a "valve".

Millennial-Scale Variability in the Indian Monsoon and Links to Ocean Circulation

NASA Astrophysics Data System (ADS)

DeLong, K. A.; Came, R. E.; Johnson, J. E.; Giosan, L.

2014-12-01

Millennial-scale variability in the Indian monsoon was temporally linked to changes in global ocean circulation during the last glacial period, as evidenced by planktic-benthic foraminiferal stable isotope and trace element results from an intermediate depth sediment core from the northwestern Bay of Bengal. Paired planktic foraminiferal Mg/Ca and δ18Oc constrain sea surface temperatures and isolate millennial-scale variations in the δ18O of surface waters (δ18Osw), which resulted from changes in river runoff in the northwestern Bay. Concurrently with low δ18Osw events, benthic foraminiferal δ13C decreased, suggesting an increased influence of an aged water mass at this intermediate depth site during the low salinity events. Benthic foraminiferal Cd/Ca results support the identification of this water mass as aged Glacial Antarctic Intermediate Water (GAAIW). Lagged correlation analysis (r= 0.41) indicates that changes in subsurface properties led changes in surface properties by an average of 380 years. The implication is that Southern Hemisphere climate exerted a controlling influence on the Indian monsoon during the last glacial period.

42 CFR 422.54 - Continuation of enrollment for MA local plans.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 3 2010-10-01 2010-10-01 false Continuation of enrollment for MA local plans. 422... Enrollment § 422.54 Continuation of enrollment for MA local plans. (a) Definition. Continuation area means an additional area (outside the service area) within which the MA organization offering a local plan furnishes...

42 CFR 422.54 - Continuation of enrollment for MA local plans.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 3 2011-10-01 2011-10-01 false Continuation of enrollment for MA local plans. 422... Enrollment § 422.54 Continuation of enrollment for MA local plans. (a) Definition. Continuation area means an additional area (outside the service area) within which the MA organization offering a local plan furnishes...

10 CFR 63.161 - Emergency plan for the geologic repository operations area through permanent closure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Emergency plan for the geologic repository operations area... OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Emergency Planning Criteria § 63.161 Emergency plan for the geologic repository operations area through permanent...

Study on the methods of rational analysis about the area of the Planning of Sea Usage of Regional Construction

NASA Astrophysics Data System (ADS)

Ya-Juan, Li; Tian-Yu, Mao; Mingjing-Tian

2018-03-01

The Planning of Sea Usage of Regional Construction is a new area, and the rational analysis about the area of which is one of its difficulties. Based on “Urban land classification and land use planning and construction standards”, the land use control index method study the rationality of the sea usage area of the whole region, by accumulating for specific land use indicators for each land type within the planning area. This paper, takeing the project named “caofeidian integrated service area” for example, make a little study on the land use control index method used by the sea usage demonstration of the planning of sea usage of regional construction. The study will be good for improving the technical methods of rational analysis about the area of the planning of sea usage of regional construction.

Transportation planning performance measures : final report.

DOT National Transportation Integrated Search

2005-10-01

Oregon transportation plans, including the statewide Oregon Transportation Plan, and current regional transportation plans for the Portland, Salem, Eugene, and Medford metropolitan areas, contain some policy areas that are not adequately addressed by...

30 CFR 219.417 - How will MMS disburse qualified OCS revenues to the coastal political subdivisions if, during any...

Code of Federal Regulations, 2011 CFR

2011-07-01

... in the 181 Area in the Eastern Gulf of Mexico Planning Area? 219.417 Section 219.417 Mineral... Mexico Planning Area? If, during any fiscal year, there are no applicable leased tracts in the 181 Area in the Eastern Gulf of Mexico Planning Area, MMS will disburse funds to the coastal political...

Performance-based planning for small metropolitan areas

DOT National Transportation Integrated Search

2015-01-31

This report provides insights on effective practices in performance based planning by Metropolitan Planning Organizations (MPOs) that plan for Urbanized Areas with populations less than 200,000. It references existing best practices research on perfo...

30 CFR 519.417 - How will BOEM calculate the percentage allocation of qualified OCS revenues to the coastal...

Code of Federal Regulations, 2012 CFR

2012-07-01

... are no applicable leased tracts in the 181 Area in the Eastern Gulf of Mexico Planning Area? 519.417... the Eastern Gulf of Mexico Planning Area? If, during any fiscal year, there are no applicable leased tracts in the 181 Area in the Eastern Gulf of Mexico Planning Area, BOEM will calculate the percentage...

30 CFR 519.417 - How will BOEM calculate the percentage allocation of qualified OCS revenues to the coastal...

Code of Federal Regulations, 2013 CFR

2013-07-01

... are no applicable leased tracts in the 181 Area in the Eastern Gulf of Mexico Planning Area? 519.417... the Eastern Gulf of Mexico Planning Area? If, during any fiscal year, there are no applicable leased tracts in the 181 Area in the Eastern Gulf of Mexico Planning Area, BOEM will calculate the percentage...

30 CFR 519.417 - How will BOEM calculate the percentage allocation of qualified OCS revenues to the coastal...

Code of Federal Regulations, 2014 CFR

2014-07-01

... are no applicable leased tracts in the 181 Area in the Eastern Gulf of Mexico Planning Area? 519.417... the Eastern Gulf of Mexico Planning Area? If, during any fiscal year, there are no applicable leased tracts in the 181 Area in the Eastern Gulf of Mexico Planning Area, BOEM will calculate the percentage...

33 CFR 103.500 - General.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MARITIME SECURITY MARITIME SECURITY: AREA MARITIME SECURITY Area Maritime Security (AMS) Plan § 103.500 General. (a) The Area Maritime... with the National Maritime Transportation Security Plan and the National Transportation Security Plan...

EPA Brownfields Area-Wide Planning Recipients Selected for FY13 Grant Funding

EPA Pesticide Factsheets

EPA has selected the following entities as Brownfields Area-Wide Planning grant recipients. These recipients will work with their local community members, other stakeholders and project partners to develop an area-wide plan and implementation strategy for

75 FR 36023 - Approval and Promulgation of Implementation Plans; Designation of Areas for Air Quality Planning...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-24

... a Maintenance Plan, Including a Contingency Plan, for the Area Under Section 175a of the CAA 1. An.... Contingency Provisions That EPA Deems Necessary to Promptly Correct Any Violation of the NAAQS That Occurs... available control measures, and contingency measures) no longer applies for so long as the area continues to...

142. ARAIII General plan of GCRE area, including electrical distribution ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

142. ARA-III General plan of GCRE area, including electrical distribution plan for power and lighting. Includes detail of floodlight and security lighting poles and fixtures. Aerojet-general 880-area/GCRE-406-1. Date: February 1958. Ineel index code no. 063-0406-00-013-102539. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

Low Impact Development Master Plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Loftin, Samuel R.

This project creates a Low Impact Development (LID) Master Plan to guide and prioritize future development of LID projects at Los Alamos National Laboratory (LANL or the Laboratory). The LID Master Plan applies to developed areas across the Laboratory and focuses on identifying opportunities for storm water quality and hydrological improvements in the heavily urbanized areas of Technical Areas 03, 35 and 53. The LID Master Plan is organized to allow the addition of LID projects for other technical areas as time and funds allow in the future.

Wilmington Area Planning Council, New Castle County, Delaware and Cecil County, Maryland : a performance-based approach to integrating congestion management into the metropolitan planning process

DOT National Transportation Integrated Search

2009-04-01

The Wilmington Area Planning Council takes an objectives-driven, performance-based approach to its metropolitan transportation planning, including paying special attention to integrating its Congestion Management Process into its planning efforts. Th...

Rural planning organizations--their role in transportation planning and project development in Texas : technical report.

DOT National Transportation Integrated Search

2010-10-01

While a formal planning and programming process is established for urbanized areas through Metropolitan : Planning Organizations, no similar requirement has been established for rural areas. Currently, under the : Safe, Accountable, Flexible, Efficie...

78 FR 52485 - Revisions to the Arizona State Implementation Plan, Maricopa County Area

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-23

...] Revisions to the Arizona State Implementation Plan, Maricopa County Area AGENCY: Environmental Protection... County Area portion of the Arizona State Implementation Plan (SIP). These revisions concern particulate matter (PM) emissions from fugitive dust sources. We are approving local statutes that regulate these...

40 CFR 300.212 - Area response drills.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 29 2013-07-01 2013-07-01 false Area response drills. 300.212 Section... PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS NATIONAL OIL AND HAZARDOUS SUBSTANCES POLLUTION CONTINGENCY PLAN Planning and Preparedness § 300.212 Area response drills. The OSC periodically shall conduct...

40 CFR 300.212 - Area response drills.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 29 2012-07-01 2012-07-01 false Area response drills. 300.212 Section... PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS NATIONAL OIL AND HAZARDOUS SUBSTANCES POLLUTION CONTINGENCY PLAN Planning and Preparedness § 300.212 Area response drills. The OSC periodically shall conduct...

78 FR 19523 - General Management Plan, Draft Environmental Impact Statement, Lake Meredith National Recreation...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-01

... Management Plan, Draft Environmental Impact Statement, Lake Meredith National Recreation Area and Alibates... Management Plan, Lake Meredith National Recreation Area and Alibates Flint Quarries National Monument, Texas... management alternatives for Lake Meredith National Recreation Area and three management alternatives for...

12 CFR 25.27 - Strategic plan.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Strategic plan. 25.27 Section 25.27 Banks and... DEPOSIT PRODUCTION REGULATIONS Regulations Standards for Assessing Performance § 25.27 Strategic plan. (a... assessment area(s) under a strategic plan if: (1) The bank has submitted the plan to the OCC as provided for...

The Greater Southern Area Health Service Tobacco Control Plan 2006-2009.

PubMed

Gow, Andrew J; Weir, Kylie M; Marich, Andrew J N

2008-01-01

In response to the NSW Tobacco Action Plan 2005-2009, Greater Southern Area Health Service (GSAHS) has developed a local plan. This short report describes how activities promoted in the state plan were prioritised and six outcomes identified as the focus for the GSAHS Tobacco Control Plan 2006-2009.

76 FR 3652 - Dog Management Plan/Environmental Impact Statement, Golden Gate National Recreation Area, California

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-20

... DEPARTMENT OF THE INTERIOR National Park Service [8145-8B90-SZM] Dog Management Plan/Environmental...: Notice of Availability of a Draft Environmental Impact Statement for the Dog Management Plan, Golden Gate... the Dog Management Plan (Draft Plan/EIS), Golden Gate National Recreation Area (GGNRA), California...

76 FR 22917 - Dog Management Plan/Draft Environmental Impact Statement, Golden Gate National Recreation Area...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-25

... DEPARTMENT OF THE INTERIOR National Park Service [NPS-PWR-PWRO--0315-696; 8145-8B90-SZM] Dog... Impact Statement/Dog Management Plan, Golden Gate National Recreation Area. SUMMARY: The National Park Service has prepared a Draft Dog Management Plan and Environmental Impact Statement (Plan/DEIS). The Plan...

77 FR 30320 - General Management Plan/Environmental Impact Statement, Ross Lake National Recreation Area, North...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-22

... Management Plan/Environmental Impact Statement, Ross Lake National Recreation Area, North Cascades National... Impact Statement for the new General Management Plan (GMP) for Ross Lake National Recreation Area, part... Wilderness Act of 1988. The full range of foreseeable environmental consequences from implementing the...

75 FR 1010 - Environmental Impact Statement: Sherburne and Stearns Counties, MN

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-07

... of 10th Street South and north of Interstate 94 in the St. Cloud Metropolitan Area, Sherburne and... Transportation Planning Manager, St. Cloud Area Planning Organization, 1040 County Road Four, St. Cloud.... Cloud Area Planning Organization and Stearns and Sherburne Counties, has terminated the Tier I EIS...

A rapid decision sampling plan for implementing area-wide management of the red palm weevil, Rhynchophorus ferrugineus, in coconut plantations of India.

PubMed

Faleiro, J R; Ashok Kumar, J

2008-01-01

The red palm weevil Rhynchophorus ferrugineus Olivier (Curculionidae/Rhynchophoridae/Dryophthoridae) is a lethal pest of young coconut palms, Cocos nucifera L. (Arecales: Arecaceae), with a highly aggregated population distribution pattern. R. ferrugineus is managed in several coconut growing countries using area-wide pheromone based programmes that need a substantial commitment of funds over a period of time. Often, decisions to implement area-wide management of R. ferrugineus are based on pheromone trap captures in surveillance traps and or infestation reports. Implementing area-wide management of this pest on the basis of such data can be inaccurate, as it may either under or over estimate the pest intensity in the field. This study presents sampling plans for rapid and accurate classification of R. ferrugineus infestation in coconut plantations of India by inspecting palms to detect infestation in a sequence until a decision to either implement or not to initiate area-wide management of R. ferrugineus can be made. The sampling plans are based on a common aggregation index of 3.45, assumed action threshold values of either 1.0 (plan A) or 0.5 (plan B) per cent infested palms and a risk factor of making the wrong decision set at 0.05. Using plans A and B, if the cumulative number of infested palms in a young 1 hectare coconut plantation is zero out of 150 palms for both plans, then area-wide management is not required, while on the other hand, if the cumulative number of infested palms for the same area is 6 (plan A), or 5 (plan B), then area-wide management of R. ferrugineus is essential. The proposed sampling plans are efficient tools in decision making, particularly at very low and high levels of infestation and can also be used to assess the performance of R. ferrugineus IPM programmes that are in progress. These plans not only save time and money as only a small area needs to be sampled to arrive at a correct decision, but are also efficient in rating the infestation level accurately.

Sex education and family planning services for young adults: alternative urban strategies in Mexico.

PubMed

Townsend, J W; Diaz de May, E; Sepúlveda, Y; Santos de Garza, Y; Rosenhouse, S

1987-01-01

In Mexico, youth face difficulties in obtaining reliable information on sex education and family planning through existing community programs. Two alternative strategies to provide these services are being tested in poor urban areas of Monterrey. In one experimental area, Integrated Youth Centers were established, which provide sex education and family planning services as well as counseling, academic tutoring, and recreational activities. In another area, trained young adults and community counselors work through informal networks to provide sex education and family planning information. Both utilization and the cost of these services are examined in the context of plans for expanding coverage in Mexico-U.S. border areas.

Williamsport Area Community College Long Range Planning: The Long Range Plan, Update 1987.

ERIC Educational Resources Information Center

Williamsport Area Community Coll., PA.

This update to Williamsport Area Community College's (WACC's) 1984-89 long-range plan offers a status report on each of the plan's 78 objectives, reassigns responsibility for specific objectives to make the plan responsive to the current organizational structure of the college, and offers 11 new objectives for the 1986-87 academic year. After…

Planning protected areas network that are relevant today and under future climate change is possible: the case of Atlantic Forest endemic birds.

PubMed

Vale, Mariana M; Souza, Thiago V; Alves, Maria Alice S; Crouzeilles, Renato

2018-01-01

A key strategy in biodiversity conservation is the establishment of protected areas. In the future, however, the redistribution of species in response to ongoing climate change is likely to affect species' representativeness in those areas. Here we quantify the effectiveness of planning protected areas network to represent 151 birds endemic to the Brazilian Atlantic Forest hotspot, under current and future climate change conditions for 2050. We combined environmental niche modeling and systematic conservation planning using both a county and a regional level planning strategy. We recognized the conflict between biodiversity conservation and economic development, including socio-economic targets (as opposed to biological only) and using planning units that are meaningful for policy-makers. We estimated an average contraction of 29,500 km 2 in environmentally suitable areas for birds, representing 52% of currently suitable areas. Still, the most cost-effective solution represented almost all target species, requiring only ca. 10% of the Atlantic Forest counties to achieve that representativeness, independent of strategy. More than 50% of these counties were selected both in the current and future planned networks, representing >83% of the species. Our results indicate that: (i) planning protected areas network currently can be useful to represent species under climate change; (ii) the overlapped planning units in the best solution for both current and future conditions can be considered as "no regret" areas; (iii) priority counties are spread throughout the biome, providing specific guidance wherever the possibility of creating protected area arises; and (iv) decisions can occur at different administrative spheres (Federal, State or County) as we found quite similar numerical solutions using either county or regional level strategies.

Planning protected areas network that are relevant today and under future climate change is possible: the case of Atlantic Forest endemic birds

PubMed Central

Souza, Thiago V.; Alves, Maria Alice S.; Crouzeilles, Renato

2018-01-01

Background A key strategy in biodiversity conservation is the establishment of protected areas. In the future, however, the redistribution of species in response to ongoing climate change is likely to affect species’ representativeness in those areas. Here we quantify the effectiveness of planning protected areas network to represent 151 birds endemic to the Brazilian Atlantic Forest hotspot, under current and future climate change conditions for 2050. Methods We combined environmental niche modeling and systematic conservation planning using both a county and a regional level planning strategy. We recognized the conflict between biodiversity conservation and economic development, including socio-economic targets (as opposed to biological only) and using planning units that are meaningful for policy-makers. Results We estimated an average contraction of 29,500 km2 in environmentally suitable areas for birds, representing 52% of currently suitable areas. Still, the most cost-effective solution represented almost all target species, requiring only ca. 10% of the Atlantic Forest counties to achieve that representativeness, independent of strategy. More than 50% of these counties were selected both in the current and future planned networks, representing >83% of the species. Discussion Our results indicate that: (i) planning protected areas network currently can be useful to represent species under climate change; (ii) the overlapped planning units in the best solution for both current and future conditions can be considered as “no regret” areas; (iii) priority counties are spread throughout the biome, providing specific guidance wherever the possibility of creating protected area arises; and (iv) decisions can occur at different administrative spheres (Federal, State or County) as we found quite similar numerical solutions using either county or regional level strategies. PMID:29844952

Comprehensive Planning.

ERIC Educational Resources Information Center

Pavlenko, Victor V.

Comprehensive planning, defined as the work of those who engage in efforts, within a delimited geographic area, to identify and order the physical, social, and economic relationships of that area, is discussed in the four sections of this paper. Section I, Introduction, describes what "planning" and "comprehensive planning" are. In Section II, Why…

Short-range transit plan for the Phoenix urbanized area : fiscal years 1982-1986

DOT National Transportation Integrated Search

1981-07-21

Report presents the FY 1980-81 update of the Phoenix, Arizona, urbanized area Short Range Transit Plan. It describes a five-year plan to guide improvements of the public transportation sytem. Planning aspects of the report will be incorporated into t...

Planning a Fieldhouse.

ERIC Educational Resources Information Center

North Carolina State Dept. of Public Instruction, Raleigh. Div. of School Planning.

Area design, plan diagrams, and planning procedures for athletic fieldhouses adopted by North Carolina schools are recommended in this guide. The fieldhouse, generally a separate building accommodating the football team, is used by other teams of both sexes during their sports season. Location should be near play areas and planned for building…

42 CFR 422.54 - Continuation of enrollment for MA local plans.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 3 2013-10-01 2013-10-01 false Continuation of enrollment for MA local plans. 422..., and Enrollment § 422.54 Continuation of enrollment for MA local plans. (a) Definition. Continuation area means an additional area (outside the service area) within which the MA organization offering a...

42 CFR 422.54 - Continuation of enrollment for MA local plans.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 3 2012-10-01 2012-10-01 false Continuation of enrollment for MA local plans. 422..., and Enrollment § 422.54 Continuation of enrollment for MA local plans. (a) Definition. Continuation area means an additional area (outside the service area) within which the MA organization offering a...

42 CFR 422.54 - Continuation of enrollment for MA local plans.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 3 2014-10-01 2014-10-01 false Continuation of enrollment for MA local plans. 422..., and Enrollment § 422.54 Continuation of enrollment for MA local plans. (a) Definition. Continuation area means an additional area (outside the service area) within which the MA organization offering a...

50 CFR Figure 1 to Subpart E of... - Sitka Local Area Management Plan

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Sitka Local Area Management Plan 1 Figure 1 to Subpart E of Part 300 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES... Part 300—Sitka Local Area Management Plan ER18JY05.000 ...

50 CFR Figure 1 to Subpart E of... - Sitka Local Area Management Plan

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Sitka Local Area Management Plan 1 Figure 1 to Subpart E of Part 300 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED ACTIVITIES... Part 300—Sitka Local Area Management Plan ER18JY05.000 ...

75 FR 57186 - Approval and Promulgation of Implementation Plans and Designations of Areas for Air Quality...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-20

... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R04-OAR-2010-0203-201035; FRL-9202-9] Approval and Promulgation of Implementation Plans and Designations of Areas for Air Quality Planning Purposes... determination that the Birmingham, Alabama, nonattainment area has attained the 24-hour fine particulate matter...

40 CFR 52.63 - PM10 State Implementation Plan development in group II areas.

Code of Federal Regulations, 2014 CFR

2014-07-01

... development in group II areas. 52.63 Section 52.63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Alabama § 52.63 PM10 State Implementation Plan development in group II areas. On March 15, 1989, the State submitted a...

40 CFR 52.881 - PM10 State implementation plan development in group II areas.

Code of Federal Regulations, 2012 CFR

2012-07-01

... development in group II areas. 52.881 Section 52.881 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Kansas § 52.881 PM10 State implementation plan development in group II areas. The state has submitted a committal SIP for...

40 CFR 52.63 - PM10 State Implementation Plan development in group II areas.

Code of Federal Regulations, 2010 CFR

2010-07-01

... development in group II areas. 52.63 Section 52.63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Alabama § 52.63 PM10 State Implementation Plan development in group II areas. On March 15, 1989, the State submitted a...

40 CFR 52.63 - PM10 State Implementation Plan development in group II areas.

Code of Federal Regulations, 2011 CFR

2011-07-01

... development in group II areas. 52.63 Section 52.63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Alabama § 52.63 PM10 State Implementation Plan development in group II areas. On March 15, 1989, the State submitted a...

40 CFR 52.935 - PM10 State implementation plan development in group II areas.

Code of Federal Regulations, 2010 CFR

2010-07-01

... development in group II areas. 52.935 Section 52.935 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Kentucky § 52.935 PM10 State implementation plan development in group II areas. On July 7, 1988, the State submitted a...

76 FR 31239 - Approval and Promulgation of Implementation Plans and Designations of Areas for Air Quality...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-31

... 40 CFR 52.1004(c), suspends the requirements for this area to submit an attainment demonstration... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R04-OAR-2011-0084-201135; FRL- 9312-5] Approval and Promulgation of Implementation Plans and Designations of Areas for Air Quality Planning...

40 CFR 52.935 - PM10 State implementation plan development in group II areas.

Code of Federal Regulations, 2014 CFR

2014-07-01

... development in group II areas. 52.935 Section 52.935 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Kentucky § 52.935 PM10 State implementation plan development in group II areas. On July 7, 1988, the State submitted a...

40 CFR 52.935 - PM10 State implementation plan development in group II areas.

Code of Federal Regulations, 2013 CFR

2013-07-01

... development in group II areas. 52.935 Section 52.935 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Kentucky § 52.935 PM10 State implementation plan development in group II areas. On July 7, 1988, the State submitted a...

40 CFR 52.881 - PM10 State implementation plan development in group II areas.

Code of Federal Regulations, 2010 CFR

2010-07-01

... development in group II areas. 52.881 Section 52.881 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Kansas § 52.881 PM10 State implementation plan development in group II areas. The state has submitted a committal SIP for...

40 CFR 52.935 - PM10 State implementation plan development in group II areas.

Code of Federal Regulations, 2011 CFR

2011-07-01

... development in group II areas. 52.935 Section 52.935 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Kentucky § 52.935 PM10 State implementation plan development in group II areas. On July 7, 1988, the State submitted a...

40 CFR 52.881 - PM10 State implementation plan development in group II areas.

Code of Federal Regulations, 2011 CFR

2011-07-01

... development in group II areas. 52.881 Section 52.881 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Kansas § 52.881 PM10 State implementation plan development in group II areas. The state has submitted a committal SIP for...

40 CFR 52.881 - PM10 State implementation plan development in group II areas.

Code of Federal Regulations, 2014 CFR

2014-07-01

... development in group II areas. 52.881 Section 52.881 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Kansas § 52.881 PM10 State implementation plan development in group II areas. The state has submitted a committal SIP for...

40 CFR 52.63 - PM10 State Implementation Plan development in group II areas.

Code of Federal Regulations, 2012 CFR

2012-07-01

... development in group II areas. 52.63 Section 52.63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Alabama § 52.63 PM10 State Implementation Plan development in group II areas. On March 15, 1989, the State submitted a...

40 CFR 52.63 - PM10 State Implementation Plan development in group II areas.

Code of Federal Regulations, 2013 CFR

2013-07-01

... development in group II areas. 52.63 Section 52.63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Alabama § 52.63 PM10 State Implementation Plan development in group II areas. On March 15, 1989, the State submitted a...

40 CFR 52.881 - PM10 State implementation plan development in group II areas.

Code of Federal Regulations, 2013 CFR

2013-07-01

... development in group II areas. 52.881 Section 52.881 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Kansas § 52.881 PM10 State implementation plan development in group II areas. The state has submitted a committal SIP for...

40 CFR 52.935 - PM10 State implementation plan development in group II areas.

Code of Federal Regulations, 2012 CFR

2012-07-01

... development in group II areas. 52.935 Section 52.935 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Kentucky § 52.935 PM10 State implementation plan development in group II areas. On July 7, 1988, the State submitted a...

75 FR 27286 - McKelvie Geographic Area Range Allotment Management Planning on the Samuel R. McKelvie National...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-14

... range allotment management planning on the McKelvie Geographic Area, Samuel R. McKelvie National Forest... DEPARTMENT OF AGRICULTURE Forest Service McKelvie Geographic Area Range Allotment Management Planning on the Samuel R. McKelvie National Forest, Bessey Ranger District in Nebraska AGENCY: Forest...

78 FR 33230 - Approval and Promulgation of Implementation Plans and Designation of Areas for Air Quality...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-04

...'') section 110(k)(3), EPA is approving a maintenance plan for the 1997 8-hour ozone standard (``San Diego 8-hour maintenance plan'') for the San Diego County 1997 ozone nonattainment area (``San Diego 8-hour... maintenance plan is included in a document titled Redesignation Request and Maintenance Plan for the 1997...

77 FR 38399 - Approval and Promulgation of Implementation Plans; Arizona; Nogales PM10

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-27

...EPA is proposing to approve a state implementation plan revision submitted by the Arizona Department of Environmental Quality to address the moderate area PM10, particulate matter with an aerodynamic diameter of less than or equal to a nominal ten micrometers, planning requirements for the Nogales nonattainment area. Consistent with this proposal, EPA is also proposing to approve the following plan elements as meeting the requirements of the Clean Air Act: the Nogales nonattainment area 2008 and 2011 emission inventories; the demonstration that the Nogales nonattainment area is attaining the National Ambient Air Quality Standard for PM10, but for international emissions sources in Nogales, Mexico; the demonstration that reasonably available control measures sufficient to meet the standard have been implemented in the nonattainment area; the reasonable further progress demonstration; the demonstration that implementation of measures beyond those needed for attainment meet the contingency measure requirement; and, the motor vehicle emissions budget for the purposes of determining the conformity of transportation plans, programs, and projects with this PM10 plan.

77 FR 73560 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia; Redesignation of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-11

... the Area. The maintenance plan includes an insignificance determination for the on-road motor vehicle... redesignation. The maintenance plan includes an insignificance determination for the on-road motor vehicle...) Nonattainment Area to Attainment and Approval of the Associated Maintenance Plan AGENCY: Environmental...

14 CFR 93.335 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES Washington, DC Metropolitan Area Special Flight Rules Area § 93.335 Definitions. For purposes of this subpart— DC FRZ flight plan is a flight plan filed... the DC FRZ. This flight plan is separate and distinct from a standard VFR flight plan, and does not...

45 CFR 1321.17 - Content of State plan.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION ON AGING, OLDER AMERICANS PROGRAMS GRANTS TO STATE AND COMMUNITY PROGRAMS ON AGING State Agency Responsibilities § 1321.17 Content of State plan. To... each planning and service area and of area agencies on aging designated for each planning and service...

45 CFR 1321.17 - Content of State plan.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION ON AGING, OLDER AMERICANS PROGRAMS GRANTS TO STATE AND COMMUNITY PROGRAMS ON AGING State Agency Responsibilities § 1321.17 Content of State plan. To... each planning and service area and of area agencies on aging designated for each planning and service...

45 CFR 1321.17 - Content of State plan.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION ON AGING, OLDER AMERICANS PROGRAMS GRANTS TO STATE AND COMMUNITY PROGRAMS ON AGING State Agency Responsibilities § 1321.17 Content of State plan. To... each planning and service area and of area agencies on aging designated for each planning and service...

78 FR 55093 - Dog Management Plan, Supplemental Environmental Impact Statement, Golden Gate National Recreation...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-09

....YP0000] Dog Management Plan, Supplemental Environmental Impact Statement, Golden Gate National Recreation... the Dog Management Plan (Plan/SEIS), Golden Gate National Recreation Area (GGNRA), California. Current dog management in the park is based on a number of factors. Areas included in the GGNRA Citizens...

7 CFR 1940.959 - Area plan.

Code of Federal Regulations, 2010 CFR

2010-01-01

... area. (b) An inventory and assessment of the human resources of the area, including, but not limited to... the plan; and (5) An analysis of the human needs of the area, the resources in the area available to... specialized job training in the area and the extent to which the training needs of the area are not being met...

Updating the transportation plans in Virginia's small urban areas.

DOT National Transportation Integrated Search

1987-01-01

The Transportation Planning Division (TPD) of the Virginia Department of Transportation is responsible for developing transportation plans for areas in the state having a population greater than 3,500. Although transportation forecasting procedures f...

76 FR 36873 - Approval and Promulgation of Implementation Plans and Designations of Areas for Air Quality...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-23

... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R04-OAR-2010-1036-201138; FRL-9322-4] Approval and Promulgation of Implementation Plans and Designations of Areas for Air Quality Planning Purposes... Atlanta, Georgia 1997 8-hour ozone nonattainment area has attained the 1997 8- hour ozone national ambient...

76 FR 18650 - Approval and Promulgation of Implementation Plans and Designations of Areas for Air Quality...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-05

... determination, in accordance with 40 CFR 52.1004(c), suspends the requirements for this area to submit an... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R04-OAR-2010-0798-201048; FRL-9288-8] Approval and Promulgation of Implementation Plans and Designations of Areas for Air Quality Planning Purposes...

76 FR 31858 - Approval and Promulgation of Implementation Plans and Designations of Areas for Air Quality...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-02

... accordance with 40 CFR 52.1004(c), suspends the requirements for this area to submit an attainment... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R04-OAR-2011-0055-201136; FRL-9313-8] Approval and Promulgation of Implementation Plans and Designations of Areas for Air Quality Planning Purposes...

76 FR 6812 - Proposed Shiloh III Wind Plant Project, Solano County, CA; Proposed Habitat Conservation Plan and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-08

... turbines and associated facilities and access roads, maintenance of the wind turbines and associated... Area). The Plan Area is adjacent to existing energy-producing facilities, most notably wind turbine.../California Independent System Operator power grid. Up to 59 wind turbines would be built in the Plan Area...

77 FR 51568 - Outer Continental Shelf, Gulf of Mexico, Oil and Gas Lease Sales, Western Planning Area Lease...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-24

... Western Planning Area (WPA) Lease Sale 233 and Central Planning Area (CPA) Lease Sale 231 (WPA/CPA... is reopening the scoping comment period. DATES: Scoping comments for this Draft WPA/CPA Supplemental...-opening of the scoping process for the WPA/CPA Supplemental EIS. Throughout the scoping process, Federal...

A Rapid Decision Sampling Plan for Implementing Area—Wide Management of the Red Palm Weevil, Rhynchophorus ferrugineus, in Coconut Plantations of India

PubMed Central

Faleiro, J. R.; Ashok Kumar, J.

2008-01-01

The red palm weevil Rhynchophorus ferrugineus Olivier (Curculionidae/Rhynchophoridae/Dryophthoridae) is a lethal pest of young coconut palms, Cocos nucifera L. (Arecales: Arecaceae), with a highly aggregated population distribution pattern. R. ferrugineus is managed in several coconut growing countries using area-wide pheromone based programmes that need a substantial commitment of funds over a period of time. Often, decisions to implement area-wide management of R. ferrugineus are based on pheromone trap captures in surveillance traps and or infestation reports. Implementing area-wide management of this pest on the basis of such data can be inaccurate, as it may either under or over estimate the pest intensity in the field. This study presents sampling plans for rapid and accurate classification of R. ferrugineus infestation in coconut plantations of India by inspecting palms to detect infestation in a sequence until a decision to either implement or not to initiate area-wide management of R. ferrugineus can be made. The sampling plans are based on a common aggregation index of 3.45, assumed action threshold values of either 1.0 (plan A) or 0.5 (plan B) per cent infested palms and a risk factor of making the wrong decision set at 0.05. Using plans A and B, if the cummulative number of infested palms in a young 1 hectare coconut plantation is zero out of 150 palms for both plans, then area-wide management is not required, while on the other hand, if the cummulative number of infested palms for the same area is 6 (plan A), or 5 (plan B), then area-wide management of R. ferrugineus is essential. The proposed sampling plans are efficient tools in decision making, particularly at very low and high levels of infestation and can also be used to assess the performance of R. ferrugineus IPM programmes that are in progress. These plans not only save time and money as only a small area needs to be sampled to arrive at a correct decision, but are also efficient in rating the infestation level accurately. PMID:20337561

The impact of family planning on primary school enrolment in sub-national areas within 25 African countries.

PubMed

Longwe, Abiba; Smits, Jeroen

2013-06-01

We study how the availability and use of family planning services in African countries influences the family planning situation of households and through this the educational participation of young children. A district panel dataset is used for 441 urban and rural areas within 233 districts of 25 countries. Path analysis shows that a decrease in the number of births is associated with an increase in educational participation in the area. The number of births is negatively associated with acceptance, knowledge and actual use of contraceptives in the area. As reversed causality and selection bias seem unlikely, the identified relationship probably is at least partially causal. Hence, investments in family planning services in poor areas are not only important because they allow women to plan their births better, but also because they may lead to higher primary enrolment rates and thus contribute to the region's future economic growth.

Structural dynamics division research and technology accomplishments for FY 1993 and plans for FY 1994

NASA Technical Reports Server (NTRS)

Wynne, Eleanor C.

1994-01-01

The purpose is to present the Structural Dynamics Division's research accomplishments for F.Y. 1993 and research plans for F.Y. 1994. The work under each Branch (technical area) is described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to 5-year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

Structural dynamics division research and technology accomplishments for FY 1989 and plans for FY 1990

NASA Technical Reports Server (NTRS)

Smith, Jacqueline G.; Gardner, James E.

1990-01-01

The purpose is to present the Structural Dynamics Division's research accomplishments for FY 1989 and research plans for FY 1990. The work under each Branch (technical area) is described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to five year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

Loads and aeroelasticity division research and technology accomplishments for FY 1985 and plans for FY 1986

NASA Technical Reports Server (NTRS)

Gardner, J. E.; Dixon, S. C.

1986-01-01

The Langley Research Center Loads and Aeroelasticity Division's research accomplishments for FY85 and research plans for FY86 are presented. The rk under each branch (technical area) will be described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to five year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

Loads and Aeroelasticity Division research and technology accomplishments for FY 1986 and plans for FY 1987

NASA Technical Reports Server (NTRS)

Gardner, James E.; Dixon, S. C.

1987-01-01

The Loads and Aeroelasticity Division's research accomplishments for FY 86 and research plans for FY 87 are presented. The work under each Branch (technical area) is described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to five year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

77 FR 69409 - Approval and Promulgation of Implementation Plans and Designation of Areas for Air Quality...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-19

...-road motor vehicle insignificance finding that is included as part of Kentucky's maintenance plan for... Plan (SIP) revision containing a maintenance plan for the Kentucky portion of the Huntington-Ashland...-Ashland Area. EPA is also proposing to approve the on-road motor vehicle insignificance finding for direct...

76 FR 56220 - Draft Environmental Impact Statement for General Management Plan for Golden Gate National...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-12

... Environmental Impact Statement for General Management Plan for Golden Gate National Recreation Area and Muir... Management Plan for Golden Gate National Recreation Area and Muir Woods National Monument. SUMMARY: In accord... Environmental Impact Statement (Draft EIS) for the updating the General Management Plan (GMP) for Golden Gate...

75 FR 1543 - Approval and Promulgation of Implementation Plans; Puerto Rico; Guaynabo PM10

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-12

...] Approval and Promulgation of Implementation Plans; Puerto Rico; Guaynabo PM 10 Limited Maintenance Plan and... approving the Limited Maintenance Plan for the Municipality of Guaynabo nonattainment area in Puerto Rico and the request by the Commonwealth of Puerto Rico to redesignate the area from nonattainment to...

40 CFR 52.1392 - Federal Implementation Plan for the Billings/Laurel Area.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 4 2013-07-01 2013-07-01 false Federal Implementation Plan for the Billings/Laurel Area. 52.1392 Section 52.1392 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Montana § 52.1392 Federal Implementation Plan for...

40 CFR 52.1392 - Federal Implementation Plan for the Billings/Laurel Area.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 4 2012-07-01 2012-07-01 false Federal Implementation Plan for the Billings/Laurel Area. 52.1392 Section 52.1392 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Montana § 52.1392 Federal Implementation Plan for...

40 CFR 52.1392 - Federal Implementation Plan for the Billings/Laurel Area.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 4 2014-07-01 2014-07-01 false Federal Implementation Plan for the Billings/Laurel Area. 52.1392 Section 52.1392 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Montana § 52.1392 Federal Implementation Plan for...

40 CFR 52.1392 - Federal Implementation Plan for the Billings/Laurel Area.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 4 2011-07-01 2011-07-01 false Federal Implementation Plan for the Billings/Laurel Area. 52.1392 Section 52.1392 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Montana § 52.1392 Federal Implementation Plan for...

Planning for Excellence: A Case Model in a Large Urban Community College District.

ERIC Educational Resources Information Center

Brown, Grace Carolyn

The strategy-oriented planning process used at Cuyahoga Community College (CCC) is described in this paper. After providing background on CCC, its enrollments, service area, annual fiscal responsibility, and long commitment to educational planning, the paper identifies five key areas for planning in the coming decades: (1) technological…

140. ARAIII Grading and drainage plan showing plot plan, including ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

140. ARA-III Grading and drainage plan showing plot plan, including berms around waste storage tank and fuel oil storage tank. Aerojet-general 880-area-GCRE-101-1. Date: February 1958. Ineel index code no. 063-0101-00-013-102507. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

78 FR 4341 - Approval and Promulgation of Implementation Plans and Designation of Areas for Air Quality...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-22

... Alabama Department of Environmental Management (ADEM), Air Division, to redesignate the Birmingham fine... implementation plan (SIP) to include the 1997 Annual PM 2.5 maintenance plan for the Birmingham Area that... action also approves the 2009 emissions inventory submitted with the maintenance plan. DATES: Effective...

78 FR 5306 - Approval and Promulgation of Implementation Plans and Designation of Areas for Air Quality...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-25

... the Alabama Department of Environmental Management (ADEM), Air Division, to redesignate the Birmingham... implementation plan (SIP) to include the 2006 24-hour PM 2.5 maintenance plan for the Birmingham Area that... action also approves the 2009 emissions inventory submitted with the maintenance plan. DATES: Effective...

76 FR 5078 - Approval and Promulgation of Air Quality Implementation Plans: Tennessee; Approval of Section 110...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-28

...) Maintenance Plan for the 1997 8-Hour Ozone Standards for the Nashville, TN, Area AGENCY: Environmental... Tennessee State Implementation Plan (SIP) concerning the maintenance plan addressing the 1997 8-hour ozone standards for the Nashville, Tennessee 1997 8-hour ozone maintenance area, which is comprised of Davidson...

33 CFR 155.4040 - Response times for each salvage and marine firefighting service.

Code of Federal Regulations, 2014 CFR

2014-07-01

... within the inland waters or the nearshore or offshore area, you must submit in writing, in your plan, the... identified in your response plan for areas OCONUS. (c) Table 155.4040(c) provides additional amplifying... on scene. vii) Salvage plan Plan completed and submitted to Incident Commander/Unified Command. (viii...

33 CFR 155.4040 - Response times for each salvage and marine firefighting service.

Code of Federal Regulations, 2012 CFR

2012-07-01

... within the inland waters or the nearshore or offshore area, you must submit in writing, in your plan, the... identified in your response plan for areas OCONUS. (c) Table 155.4040(c) provides additional amplifying... on scene. vii) Salvage plan Plan completed and submitted to Incident Commander/Unified Command. (viii...

33 CFR 155.4040 - Response times for each salvage and marine firefighting service.

Code of Federal Regulations, 2013 CFR

2013-07-01

... within the inland waters or the nearshore or offshore area, you must submit in writing, in your plan, the... identified in your response plan for areas OCONUS. (c) Table 155.4040(c) provides additional amplifying... on scene. vii) Salvage plan Plan completed and submitted to Incident Commander/Unified Command. (viii...

12 CFR 563b.105 - What information must I include in my business plan?

Code of Federal Regulations, 2010 CFR

2010-01-01

... achieve your planned deployment of conversion proceeds in your proposed market areas, and how your... lending needs in your proposed market areas. OTS strongly discourages business plans that provide for a... properly managed leverage strategy. (3) The risks associated with your plan for deployment of conversion...

75 FR 77655 - Notice of Proposed Supplementary Rules for Public Lands in Colorado: Saguache, Alamosa, Rio...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-13

... included in the San Luis Resource Area Travel Management Plan (TMP), approved on June 4, 2009. These... Luis Resource Area Travel Management Plan'' in the subject line). FOR FURTHER INFORMATION CONTACT... Resource Valley Travel Management Plan and Amend San Luis Valley Resource Management Plan and Start the...

Enhanced planning review of the St. Louis metropolitan area

DOT National Transportation Integrated Search

1996-06-01

The Intermodal Surface Transportation Act of 1991 (ISTEA) introduced an era of : dynamic change in metropolitan transportation planning. This report on : transportation planning in the St. Louis (Missouri) Metropolitan Area is the : ninth in a series...

Cloning, expression, and biochemical characterization of a novel NADP+-dependent 7α-hydroxysteroid dehydrogenase from Clostridium difficile and its application for the oxidation of bile acids.

PubMed

Bakonyi, Daniel; Hummel, Werner

2017-04-01

A gene encoding a novel 7α-specific NADP + -dependent hydroxysteroid dehydrogenase from Clostridium difficile was cloned and heterologously expressed in Escherichia coli. The enzyme was purified using an N-terminal hexa-his-tag and biochemically characterized. The optimum temperature is at 60°C, but the enzyme is inactivated at this temperature with a half-life time of 5min. Contrary to other known 7α-HSDHs, for example from Clostridium sardiniense or E. coli, the enzyme from C. difficile does not display a substrate inhibition. In order to demonstrate the applicability of this enzyme, a small-scale biotransformation of the bile acid chenodeoxycholic acid (CDCA) into 7-ketolithocholic acid (7-KLCA) was carried out with simultaneous regeneration of NADP + using an NADPH oxidase that resulted in a complete conversion (<99%). Furthermore, by a structure-based site-directed mutagenesis, cofactor specificity of the 7α-HSDH from Clostridium difficile was altered to accept NAD(H). This mutant was biochemically characterized and compared to the wild-type. Copyright © 2016. Published by Elsevier Inc.

High-performance liquid chromatographic determination of ursodeoxycholic acid after solid phase extraction of blood serum and detection-oriented derivatization.

PubMed

Nobilis, M; Pour, M; Kunes, J; Kopecký, J; Kvĕtina, J; Svoboda, Z; Sládková, K; Vortel, J

2001-03-01

Ursodeoxycholic acid (3 alpha,7 beta-dihydroxy-5 beta-cholanoic acid, UDCA) is a therapeutically applicable bile acid widely used for the dissolution of cholesterol-rich gallstones and in the treatment of chronic liver diseases associated with cholestasis. UDCA is more hydrophilic and less toxic than another therapeutically valuable bile acid, chenodeoxycholic acid (CDCA), the 7 alpha-epimer of UDCA. Procedures for sample preparation and HPLC determination of UDCA in blood serum were developed and validated. A higher homologue of UDCA containing an additional methylene group in the side chain was synthetized and used as an internal standard (IS). Serum samples with IS were diluted with a buffer (pH=7). The bile acids and IS were captured using solid phase extraction (C18 cartridges). The carboxylic group of the analytes was derivatized using 2-bromo-2'-acetonaphthone (a detection-oriented derivatization), and reaction mixtures were analyzed (HPLC with UV 245 nm detection; a 125--4 mm column containing Lichrospher 100 C18, 5 microm; mobile phase: acetonitrile--water, 6:4 (v/v)). Following validation, this method was used for pharmacokinetic studies of UDCA in humans.

Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer.

PubMed

Lawrenson, Kate; Li, Qiyuan; Kar, Siddhartha; Seo, Ji-Heui; Tyrer, Jonathan; Spindler, Tassja J; Lee, Janet; Chen, Yibu; Karst, Alison; Drapkin, Ronny; Aben, Katja K H; Anton-Culver, Hoda; Antonenkova, Natalia; Baker, Helen; Bandera, Elisa V; Bean, Yukie; Beckmann, Matthias W; Berchuck, Andrew; Bisogna, Maria; Bjorge, Line; Bogdanova, Natalia; Brinton, Louise A; Brooks-Wilson, Angela; Bruinsma, Fiona; Butzow, Ralf; Campbell, Ian G; Carty, Karen; Chang-Claude, Jenny; Chenevix-Trench, Georgia; Chen, Anne; Chen, Zhihua; Cook, Linda S; Cramer, Daniel W; Cunningham, Julie M; Cybulski, Cezary; Dansonka-Mieszkowska, Agnieszka; Dennis, Joe; Dicks, Ed; Doherty, Jennifer A; Dörk, Thilo; du Bois, Andreas; Dürst, Matthias; Eccles, Diana; Easton, Douglas T; Edwards, Robert P; Eilber, Ursula; Ekici, Arif B; Fasching, Peter A; Fridley, Brooke L; Gao, Yu-Tang; Gentry-Maharaj, Aleksandra; Giles, Graham G; Glasspool, Rosalind; Goode, Ellen L; Goodman, Marc T; Grownwald, Jacek; Harrington, Patricia; Harter, Philipp; Hasmad, Hanis Nazihah; Hein, Alexander; Heitz, Florian; Hildebrandt, Michelle A T; Hillemanns, Peter; Hogdall, Estrid; Hogdall, Claus; Hosono, Satoyo; Iversen, Edwin S; Jakubowska, Anna; James, Paul; Jensen, Allan; Ji, Bu-Tian; Karlan, Beth Y; Kruger Kjaer, Susanne; Kelemen, Linda E; Kellar, Melissa; Kelley, Joseph L; Kiemeney, Lambertus A; Krakstad, Camilla; Kupryjanczyk, Jolanta; Lambrechts, Diether; Lambrechts, Sandrina; Le, Nhu D; Lee, Alice W; Lele, Shashi; Leminen, Arto; Lester, Jenny; Levine, Douglas A; Liang, Dong; Lissowska, Jolanta; Lu, Karen; Lubinski, Jan; Lundvall, Lene; Massuger, Leon F A G; Matsuo, Keitaro; McGuire, Valerie; McLaughlin, John R; Nevanlinna, Heli; McNeish, Ian; Menon, Usha; Modugno, Francesmary; Moysich, Kirsten B; Narod, Steven A; Nedergaard, Lotte; Ness, Roberta B; Azmi, Mat Adenan Noor; Odunsi, Kunle; Olson, Sara H; Orlow, Irene; Orsulic, Sandra; Weber, Rachel Palmieri; Pearce, Celeste L; Pejovic, Tanja; Pelttari, Liisa M; Permuth-Wey, Jennifer; Phelan, Catherine M; Pike, Malcolm C; Poole, Elizabeth M; Ramus, Susan J; Risch, Harvey A; Rosen, Barry; Rossing, Mary Anne; Rothstein, Joseph H; Rudolph, Anja; Runnebaum, Ingo B; Rzepecka, Iwona K; Salvesen, Helga B; Schildkraut, Joellen M; Schwaab, Ira; Sellers, Thomas A; Shu, Xiao-Ou; Shvetsov, Yurii B; Siddiqui, Nadeem; Sieh, Weiva; Song, Honglin; Southey, Melissa C; Sucheston, Lara; Tangen, Ingvild L; Teo, Soo-Hwang; Terry, Kathryn L; Thompson, Pamela J; Timorek, Agnieszka; Tsai, Ya-Yu; Tworoger, Shelley S; van Altena, Anne M; Van Nieuwenhuysen, Els; Vergote, Ignace; Vierkant, Robert A; Wang-Gohrke, Shan; Walsh, Christine; Wentzensen, Nicolas; Whittemore, Alice S; Wicklund, Kristine G; Wilkens, Lynne R; Woo, Yin-Ling; Wu, Xifeng; Wu, Anna H; Yang, Hannah; Zheng, Wei; Ziogas, Argyrios; Monteiro, Alvaro; Pharoah, Paul D; Gayther, Simon A; Freedman, Matthew L

2015-09-22

Genome-wide association studies have reported 11 regions conferring risk of high-grade serous epithelial ovarian cancer (HGSOC). Expression quantitative trait locus (eQTL) analyses can identify candidate susceptibility genes at risk loci. Here we evaluate cis-eQTL associations at 47 regions associated with HGSOC risk (P≤10(-5)). For three cis-eQTL associations (P<1.4 × 10(-3), FDR<0.05) at 1p36 (CDC42), 1p34 (CDCA8) and 2q31 (HOXD9), we evaluate the functional role of each candidate by perturbing expression of each gene in HGSOC precursor cells. Overexpression of HOXD9 increases anchorage-independent growth, shortens population-doubling time and reduces contact inhibition. Chromosome conformation capture identifies an interaction between rs2857532 and the HOXD9 promoter, suggesting this SNP is a leading causal variant. Transcriptomic profiling after HOXD9 overexpression reveals enrichment of HGSOC risk variants within HOXD9 target genes (P=6 × 10(-10) for risk variants (P<10(-4)) within 10 kb of a HOXD9 target gene in ovarian cells), suggesting a broader role for this network in genetic susceptibility to HGSOC.

Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer

PubMed Central

Lawrenson, Kate; Li, Qiyuan; Kar, Siddhartha; Seo, Ji-Heui; Tyrer, Jonathan; Spindler, Tassja J.; Lee, Janet; Chen, Yibu; Karst, Alison; Drapkin, Ronny; Aben, Katja K. H.; Anton-Culver, Hoda; Antonenkova, Natalia; Bowtell, David; Webb, Penelope M.; deFazio, Anna; Baker, Helen; Bandera, Elisa V.; Bean, Yukie; Beckmann, Matthias W.; Berchuck, Andrew; Bisogna, Maria; Bjorge, Line; Bogdanova, Natalia; Brinton, Louise A.; Brooks-Wilson, Angela; Bruinsma, Fiona; Butzow, Ralf; Campbell, Ian G.; Carty, Karen; Chang-Claude, Jenny; Chenevix-Trench, Georgia; Chen, Anne; Chen, Zhihua; Cook, Linda S.; Cramer, Daniel W.; Cunningham, Julie M.; Cybulski, Cezary; Dansonka-Mieszkowska, Agnieszka; Dennis, Joe; Dicks, Ed; Doherty, Jennifer A.; Dörk, Thilo; du Bois, Andreas; Dürst, Matthias; Eccles, Diana; Easton, Douglas T.; Edwards, Robert P.; Eilber, Ursula; Ekici, Arif B.; Fasching, Peter A.; Fridley, Brooke L.; Gao, Yu-Tang; Gentry-Maharaj, Aleksandra; Giles, Graham G.; Glasspool, Rosalind; Goode, Ellen L.; Goodman, Marc T.; Grownwald, Jacek; Harrington, Patricia; Harter, Philipp; Hasmad, Hanis Nazihah; Hein, Alexander; Heitz, Florian; Hildebrandt, Michelle A. T.; Hillemanns, Peter; Hogdall, Estrid; Hogdall, Claus; Hosono, Satoyo; Iversen, Edwin S.; Jakubowska, Anna; James, Paul; Jensen, Allan; Ji, Bu-Tian; Karlan, Beth Y.; Kruger Kjaer, Susanne; Kelemen, Linda E.; Kellar, Melissa; Kelley, Joseph L.; Kiemeney, Lambertus A.; Krakstad, Camilla; Kupryjanczyk, Jolanta; Lambrechts, Diether; Lambrechts, Sandrina; Le, Nhu D.; Lee, Alice W.; Lele, Shashi; Leminen, Arto; Lester, Jenny; Levine, Douglas A.; Liang, Dong; Lissowska, Jolanta; Lu, Karen; Lubinski, Jan; Lundvall, Lene; Massuger, Leon F. A. G.; Matsuo, Keitaro; McGuire, Valerie; McLaughlin, John R.; Nevanlinna, Heli; McNeish, Ian; Menon, Usha; Modugno, Francesmary; Moysich, Kirsten B.; Narod, Steven A.; Nedergaard, Lotte; Ness, Roberta B.; Azmi, Mat Adenan Noor; Odunsi, Kunle; Olson, Sara H.; Orlow, Irene; Orsulic, Sandra; Weber, Rachel Palmieri; Pearce, Celeste L.; Pejovic, Tanja; Pelttari, Liisa M.; Permuth-Wey, Jennifer; Phelan, Catherine M.; Pike, Malcolm C.; Poole, Elizabeth M.; Ramus, Susan J.; Risch, Harvey A.; Rosen, Barry; Rossing, Mary Anne; Rothstein, Joseph H.; Rudolph, Anja; Runnebaum, Ingo B.; Rzepecka, Iwona K.; Salvesen, Helga B.; Schildkraut, Joellen M.; Schwaab, Ira; Sellers, Thomas A.; Shu, Xiao-Ou; Shvetsov, Yurii B.; Siddiqui, Nadeem; Sieh, Weiva; Song, Honglin; Southey, Melissa C.; Sucheston, Lara; Tangen, Ingvild L.; Teo, Soo-Hwang; Terry, Kathryn L.; Thompson, Pamela J.; Timorek, Agnieszka; Tsai, Ya-Yu; Tworoger, Shelley S.; van Altena, Anne M.; Van Nieuwenhuysen, Els; Vergote, Ignace; Vierkant, Robert A.; Wang-Gohrke, Shan; Walsh, Christine; Wentzensen, Nicolas; Whittemore, Alice S.; Wicklund, Kristine G.; Wilkens, Lynne R.; Woo, Yin-Ling; Wu, Xifeng; Wu, Anna H.; Yang, Hannah; Zheng, Wei; Ziogas, Argyrios; Monteiro, Alvaro; Pharoah, Paul D.; Gayther, Simon A.; Freedman, Matthew L.

2015-01-01

Genome-wide association studies have reported 11 regions conferring risk of high-grade serous epithelial ovarian cancer (HGSOC). Expression quantitative trait locus (eQTL) analyses can identify candidate susceptibility genes at risk loci. Here we evaluate cis-eQTL associations at 47 regions associated with HGSOC risk (P≤10−5). For three cis-eQTL associations (P<1.4 × 10−3, FDR<0.05) at 1p36 (CDC42), 1p34 (CDCA8) and 2q31 (HOXD9), we evaluate the functional role of each candidate by perturbing expression of each gene in HGSOC precursor cells. Overexpression of HOXD9 increases anchorage-independent growth, shortens population-doubling time and reduces contact inhibition. Chromosome conformation capture identifies an interaction between rs2857532 and the HOXD9 promoter, suggesting this SNP is a leading causal variant. Transcriptomic profiling after HOXD9 overexpression reveals enrichment of HGSOC risk variants within HOXD9 target genes (P=6 × 10−10 for risk variants (P<10−4) within 10 kb of a HOXD9 target gene in ovarian cells), suggesting a broader role for this network in genetic susceptibility to HGSOC. PMID:26391404

Ecological planning of urbanized areas in the south of the Far East (Birobidzhan city as an example)

NASA Astrophysics Data System (ADS)

Kalmanova, V. B.

2018-01-01

Ecological planning of urbanized areas is an urgent demand of the time, because more than 70% of Russia’s population lives in cities. The article describes that the city’s ecological planning is an important part of the area’s organization in its development strategy. The principles and features of the urban area’s ecological organization are proposed. The basis for environmental planning is the ecological and functional zoning of urban areas. The algorithm of ecological-functional zoning is developed to optimize the quality of the urban environment. Based on it, it is possible to identify the planning structure’s features, justify anthropogenic pressure on the natural components of the urban environment, etc. The article briefly presents the possibility of using the main conditions of the ecological framework in the planning of urban areas. Considering the perspective trends of the formation and development of cities in the south of the Far East, the ecological problems caused by regional natural and anthropogenic causes (features of relief, climate, functional-planning structure) are considered. The need for environmental planning of cities in the south of the Far East is shown. The results of the ecological framework’s formation of Birobidzhan city based on its ecological and functional zoning are described. The total area of open unreformed spaces in the city is calculated to be 60.8%, which can serve as the main elements of the ecological framework and perspective reserve areas for ecological planning. The cartographic model of Birobidzhan’s ecological framework is presented, which is the result and model of this type of planning. The practical use of the proposed model will facilitate the adoption of effective management decisions aimed at stabilized development of the city.

Efficient expansion of global protected areas requires simultaneous planning for species and ecosystems

PubMed Central

Polak, Tal; Watson, James E. M.; Fuller, Richard A.; Joseph, Liana N.; Martin, Tara G.; Possingham, Hugh P.; Venter, Oscar; Carwardine, Josie

2015-01-01

The Convention on Biological Diversity (CBD)'s strategic plan advocates the use of environmental surrogates, such as ecosystems, as a basis for planning where new protected areas should be placed. However, the efficiency and effectiveness of this ecosystem-based planning approach to adequately capture threatened species in protected area networks is unknown. We tested the application of this approach in Australia according to the nation's CBD-inspired goals for expansion of the national protected area system. We set targets for ecosystems (10% of the extent of each ecosystem) and threatened species (variable extents based on persistence requirements for each species) and then measured the total land area required and opportunity cost of meeting those targets independently, sequentially and simultaneously. We discover that an ecosystem-based approach will not ensure the adequate representation of threatened species in protected areas. Planning simultaneously for species and ecosystem targets delivered the most efficient outcomes for both sets of targets, while planning first for ecosystems and then filling the gaps to meet species targets was the most inefficient conservation strategy. Our analysis highlights the pitfalls of pursuing goals for species and ecosystems non-cooperatively and has significant implications for nations aiming to meet their CBD mandated protected area obligations. PMID:26064645

[Evaluation of land resources carrying capacity of development zone based on planning environment impact assessment].

PubMed

Fu, Shi-Feng; Zhang, Ping; Jiang, Jin-Long

2012-02-01

Assessment of land resources carrying capacity is the key point of planning environment impact assessment and the main foundation to determine whether the planning could be implemented or not. With the help of the space analysis function of Geographic Information System, and selecting altitude, slope, land use type, distance from resident land, distance from main traffic roads, and distance from environmentally sensitive area as the sensitive factors, a comprehensive assessment on the ecological sensitivity and its spatial distribution in Zhangzhou Merchants Economic and Technological Development Zone, Fujian Province of East China was conducted, and the assessment results were combined with the planning land layout diagram for the ecological suitability analysis. In the Development Zone, 84.0% of resident land, 93.1% of industrial land, 86.0% of traffic land, and 76. 0% of other constructive lands in planning were located in insensitive and gently sensitive areas, and thus, the implement of the land use planning generally had little impact on the ecological environment, and the land resources in the planning area was able to meet the land use demand. The assessment of the population carrying capacity with ecological land as the limiting factor indicated that in considering the highly sensitive area and 60% of the moderately sensitive area as ecological land, the population within the Zone in the planning could reach 240000, and the available land area per capita could be 134.0 m2. Such a planned population scale is appropriate, according to the related standards of constructive land.

Assisting a College's Service Area in the Transition to the New Technology Society through Strategic Planning and Management.

ERIC Educational Resources Information Center

Groff, Warren H.

North Central Technical College's (NCTC's) strategic planning and human resource development model is described in this paper in terms of its role in assisting the college's service area in adapting to new technologies. First, background information is presented on NCTC's planning process with respect to the strategic goal areas of: (1)…

Metropolitan planning organizations in Texas : overview and profiles : final report.

DOT National Transportation Integrated Search

2017-04-01

A metropolitan planning organization (MPO) has authority and responsibility for regional transportation planning in urbanized areas where the population is at least 50,000 and surrounding areas meet size/density criteria determined by the U.S. Census...

78 FR 59841 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia; West Virginia's...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-30

...EPA is approving a redesignation request and State Implementation Plan (SIP) revision submitted by the State of West Virginia. The West Virginia Department of Environmental Protection (WVDEP) requested that the West Virginia portion of the Wheeling, WV-OH fine particulate matter (PM2.5) nonattainment area (``Wheeling Area'' or ``Area'') be redesignated as attainment for the 1997 annual PM2.5 national ambient air quality standard (NAAQS). In this rulemaking action, EPA is approving the 1997 annual PM2.5 redesignation request for the West Virginia portion of the Area. EPA is also approving the maintenance plan SIP revision that the State submitted in conjunction with its redesignation request. The maintenance plan provides for continued attainment of the 1997 annual PM2.5 NAAQS for 10 years after redesignation of the West Virginia portion of the Area. The maintenance plan includes a comprehensive emissions inventory that EPA is approving in this rulemaking. The maintenance plan also includes an insignificance determination for the onroad motor vehicle contribution of PM2.5, nitrogen oxides (NOX), and sulfur dioxide (SO2) for the West Virginia portion of the Area for purposes of transportation conformity. EPA is also approving West Virginia's insignificance determination for transportation conformity. In addition, EPA is also finding that the Area continues to attain the standard. This rulemaking action approving the 1997 annual PM2.5 NAAQS redesignation request, maintenance plan, comprehensive emissions inventory, and insignificance determination for transportation conformity for the West Virginia portion of the Area is based on EPA's determination that the Area has met the criteria for redesignation to attainment specified in the Clean Air Act (CAA).

Columbia Basin Wildlife Mitigation Project : Rainwater Wildlife Area Final Management Plan.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Childs, Allen

This Draft Management Plan has been developed by the Confederated Tribes of the Umatilla Indian Reservation (CTUIR) to document how the Rainwater Wildlife Area (formerly known as the Rainwater Ranch) will be managed. The plan has been developed under a standardized planning process developed by the Bonneville Power Administration (BPA) for Columbia River Basin Wildlife Mitigation Projects (See Appendix A and Guiding Policies Section below). The plan outlines the framework for managing the project area, provides an assessment of existing conditions and key resource issues, and presents an array of habitat management and enhancement strategies. The plan culminates into amore » 5-Year Action Plan that will focus our management actions and prioritize funding during the Fiscal 2001-2005 planning period. This plan is a product of nearly two years of field studies and research, public scoping, and coordination with the Rainwater Advisory Committee. The committee consists of representatives from tribal government, state agencies, local government, public organizations, and members of the public. The plan is organized into several sections with Chapter 1 providing introductory information such as project location, purpose and need, project goals and objectives, common elements and assumptions, coordination efforts and public scoping, and historical information about the project area. Key issues are presented in Chapter 2 and Chapter 3 discusses existing resource conditions within the wildlife area. Chapter 4 provides a detailed presentation on management activities and Chapter 5 outlines a monitoring and evaluation plan for the project that will help assess whether the project is meeting the intended purpose and need and the goals and objectives. Chapter 6 displays the action plan and provides a prioritized list of actions with associated budget for the next five year period. Successive chapters contain appendices, references, definitions, and a glossary.« less

5 CFR 894.801 - Will benefits be available in underserved areas?

Code of Federal Regulations, 2011 CFR

2011-01-01

... SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES DENTAL AND VISION INSURANCE PROGRAM Benefits in Underserved Areas § 894.801 Will benefits be available in underserved areas? (a) Dental and vision plans under... underserved areas. (b) In any area where a FEDVIP dental or vision plan does not meet OPM access standards...

5 CFR 894.801 - Will benefits be available in underserved areas?

Code of Federal Regulations, 2010 CFR

2010-01-01

... SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES DENTAL AND VISION INSURANCE PROGRAM Benefits in Underserved Areas § 894.801 Will benefits be available in underserved areas? (a) Dental and vision plans under... underserved areas. (b) In any area where a FEDVIP dental or vision plan does not meet OPM access standards...

National Action Plan on Superconductivity Research and Development

NASA Astrophysics Data System (ADS)

1989-12-01

The Superconductivity Action Plan pursuant to the Superconductivity and Competitiveness Act of 1988 is presented. The plan draws upon contributions from leaders in the technical community of the Federal Government responsible for research and development in superconductivity programs, as well as from the report of the Committee to Advise the President on Superconductivity. Input from leaders in the private sector was obtained during the formulation and review of the plan. Some contents: Coordination of the plan; Technical areas (high temperature superconductivity materials in general, high temperature superconductivity films for sensors and electronics, magnets, large area high temperature superconductivity films, bulk conductors); and Policy areas.

45 CFR 1321.59 - Submission of an area plan and plan amendments to the State for approval.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 4 2010-10-01 2010-10-01 false Submission of an area plan and plan amendments to the State for approval. 1321.59 Section 1321.59 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION...

45 CFR 1321.59 - Submission of an area plan and plan amendments to the State for approval.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 4 2014-10-01 2014-10-01 false Submission of an area plan and plan amendments to the State for approval. 1321.59 Section 1321.59 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION...

45 CFR 1321.59 - Submission of an area plan and plan amendments to the State for approval.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 4 2012-10-01 2012-10-01 false Submission of an area plan and plan amendments to the State for approval. 1321.59 Section 1321.59 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION...

45 CFR 1321.59 - Submission of an area plan and plan amendments to the State for approval.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 4 2013-10-01 2013-10-01 false Submission of an area plan and plan amendments to the State for approval. 1321.59 Section 1321.59 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION...

A Planning Model for the Development of Programs for Abused and Neglected Children in Rural Areas.

ERIC Educational Resources Information Center

Chamberlain, William A.

Described are planning steps involved in developing programs for abused and neglected children in rural areas. Among barriers cited are economic factors and resistance to social planning. Emphasized is the need for congruence among local and regional agencies and organizations. Analyzed are six planning stages: entry, in which consultants gain…

45 CFR 1321.59 - Submission of an area plan and plan amendments to the State for approval.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 4 2011-10-01 2011-10-01 false Submission of an area plan and plan amendments to the State for approval. 1321.59 Section 1321.59 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION...

Omaha Metropolitan Area, ITS Early Deployment Planning Study, Strategic Deployment Plan, Appendices E: Deployment Scenarios, F: Project Descriptions, G: Support Technologies, H: Cost Estimate Assumptions

DOT National Transportation Integrated Search

1995-12-15

THE OBJECTIVE OF THE OMAHA INTELLIGENT TRANSPORTATION (ITS) EARLY DEPLOYMENT STUDY IS TO DEVELOP A STRATEGIC PLAN FOR THE DEPLOYMENT OF ITS TECHNOLOGIES IN THE OMAHA METROPOLITAN AREA. THE PLAN WILL IDENTIFY THE ITS USER SERVICES THAT WILL BE MOST BE...

Austin area-wide IVHS plan and IH-35 corridor deployment plan

DOT National Transportation Integrated Search

1998-02-01

This report describes efforts towards developing an intelligent transportation systems (ITS) deployment plan for the Austin metropolitan area in Texas. ITS issues, strategies, and technologies are discussed. The focus of the study is to support the f...

National parks and protected areas: Appoaches for balancing social, economic, and ecological values

USGS Publications Warehouse

Prato, Tony; Fagre, Daniel B.

2005-01-01

National Parks and Protected Areas: Approaches for Balancing Social, Economic and Ecological Values is peerless in its unified treatment of the issues surrounding this subject. From decision-making for planning and management to the principles of ecology and economics, this text examines the analytical methods, information technologies, and planning and management problems associated with protected area planning and management. Protected area managers and students in undergraduate and graduate courses in natural resource management will appreciate this highly readable book.

76 FR 6327 - Restricted Area, Potomac River, Marine Corps Base Quantico, Quantico, VA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-04

... public health by preventing vessels from disturbing a planned environmental remediation area that is... planned environmental remediation area that is located to the northeast of MCAF. The proposed rule was...

Risk Quantification of Systems Engineering Documents Improves Probability of DOD Project Success

DTIC Science & Technology

2009-09-01

comprehensive risk model for DoD milestone review documentation as well as recommended changes to the Capability Maturity Model Integration ( CMMI ) Project...Milestone Documentation, Project Planning, Rational Frame, Political Frame, CMMI Project Planning Process Area, CMMI Risk Management Process Area...well as recommended changes to the Capability Maturity Model Integration ( CMMI ) Project Planning and Risk Management process areas. The intent is to

77 FR 18260 - Outer Continental Shelf (OCS), Alaska OCS Region, Cook Inlet Planning Area, Proposed Oil and Gas...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-27

... OCS Region, Cook Inlet Planning Area, Proposed Oil and Gas Lease Sale 244 for OCS Oil and Gas Leasing...) identifies Sale 244 as a potential special interest sale for the Cook Inlet Planning Area in Alaska. While...-central region of the state, as evidenced by acreage leased in state sales and announced discoveries of...

76 FR 82319 - Gulf of Mexico (GOM), Outer Continental Shelf (OCS), Western Planning Area (WPA) and Central...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-30

... Continental Shelf (OCS), Western Planning Area (WPA) and Central Planning Area (CPA), Oil and Gas Lease Sales... prepared a Draft EIS on oil and gas lease sales tentatively scheduled in 2012-2017 in the WPA and CPA... scheduled for the WPA and five annual areawide lease sales are scheduled for the CPA. The proposed WPA lease...

Structural dynamics division research and technology accomplishments for FY 1992 and plans for FY 1993

NASA Technical Reports Server (NTRS)

Wynne, Eleanor C.

1993-01-01

The purpose of this paper is to present the Structural Dynamics Division's research accomplishments for F.Y. 1992 and research plans for F.Y. 1993. The work under each Branch (technical area) is described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to 5-year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

Loads and aeroelasticity division research and technology accomplishments for FY 1987 and plans for FY 1988

NASA Technical Reports Server (NTRS)

Dixon, S. C.; Gardner, James E.

1988-01-01

The purpose of this paper is to present the Loads and Aeroelasticity Division's research accomplishments for FY87 and research plans for FY88. The work under each Branch (technical area) is described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to five year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

Mississippi National River and Recreation Area Water Trail Plan.

DOT National Transportation Integrated Search

2017-05-05

The Water Trail Plan describes the current conditions of and future plans for the Mississippi National River and Recreation Area (NRRA), a 72-mile stretch of the Mississippi River running through the Twin Cities region of Minnesota. In 2012, the NRRA...

Planning through Partnerships : Alternative Transportation at Boston Harbor Islands National Park Area

DOT National Transportation Integrated Search

2004-07-31

This case study tells the story of a successful and collaborative transportation planning process at Boston Harbor Islands National Park Area (Boston Harbor Islands). By using an innovative approach to planning, Boston Harbor Islands has been able to...

Des Moines metropolitan area ITS strategic plan : executive summary

DOT National Transportation Integrated Search

1997-12-01

This is an executive summary of a strategic plan for deploying Intelligent Transportation Systems (ITS) technology in the Des Moines metropolitan area. The plan was developed as part of the Des Moines ITS Early Deployment Study (EDS). ITS is the use ...

Des Moines metropolitan area ITS strategic plan

DOT National Transportation Integrated Search

1998-08-19

The Des Moines Area Metropolitan Organization (MPO) completed an early deployment study for the Des Moines metropolitan area in late 1997. The purpose of the study was to develop a strategic plan for Intelligent Transportation Systems (ITS) deploymen...

Weather support area, floor plan and details. ("Alter COC, Bldg. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Weather support area, floor plan and details. ("Alter COC, Bldg. 2605, Weather Support Area, Floor Plan & Details" Also includes a site plan and a finish schedule. The exact location of this construction is obscure, but it appears to be the enclosure of space at the north end of room 101, the "Display Area" or "War Room") Strategic Air Command, Civil Engineering. Drawing no. B-1081, sheet no. 1 of 2, 9 July 1968; project no. MAR-132-8; CE-562; file drawer 2605-9, also 1315. Various scales. 29x41 inches. pencil on paper - March Air Force Base, Strategic Air Command, Combat Operations Center, 5220 Riverside Drive, Moreno Valley, Riverside County, CA

Determinants of contraceptives use amongst youth: an exploratory study with family planning service providers in Karachi Pakistan.

PubMed

Nishtar, Noureen Aleem; Sami, Neelofar; Alim, Sabina; Pradhan, Nousheen; Hasnain, Farid Ul

2013-01-05

In Pakistan, Contraceptive Prevalence Rate (CPR) among married female youth is 17.4% and even lower in rural and slum areas leading to rapid population growth on one hand and poor health consequences on the other. The study was conducted to explore family planning service providers' perceptions regarding use of different contraceptive methods and to identify factors that are influencing their use amongst currently married youth aged 18-24 years in slum areas of Karachi. Qualitative exploratory study design was adopted and a total of ten in-depth interviews were conducted with family planning service providers of the area. For content analysis coding of transcribed interviews was done and then categories were made and furthermore themes were derived. Our findings revealed that family planning service providers perceived that there is low use of contraceptive methods amongst youth of study area and low usage could be due to side effects; myths and misconceptions; lack of proper knowledge about different contraceptives; unmet needs of contraceptives; socio-cultural and religious factors about different contraceptive methods and family planning service providers own biases against or for use of contraceptive methods amongst youth in the study area. However better education of youth and family planning service providers' improved knowledge about counseling and use of contraceptive methods was perceived to be associated with improved use of family planning methods amongst youth of the study area. Exaggerated side effects and socio-cultural factors could be important influences leading to low use of family planning methods amongst youth of Karachi. Some policy initiatives are the training of lady health Workers, lady health visitors, physicians and staff of the pharmacies for counseling youth in the correct use of family planning methods.

Determinants of Contraceptives Use amongst Youth: An Exploratory Study with Family Planning Service Providers in Karachi Pakistan

PubMed Central

Nishtar, Noureen Aleem; Sami, Neelofar; Alim, Sabina; Pradhan, Nousheen; Farid-Ul-Hasnain

2013-01-01

Introduction: In Pakistan, Contraceptive Prevalence Rate (CPR) among married female youth is 17.4% and even lower in rural and slum areas leading to rapid population growth on one hand and poor health consequences on the other. The study was conducted to explore family planning service providers’ perceptions regarding use of different contraceptive methods and to identify factors that are influencing their use amongst currently married youth aged 18-24 years in slum areas of Karachi. Method: Qualitative exploratory study design was adopted and a total of ten in-depth interviews were conducted with family planning service providers of the area. For content analysis coding of transcribed interviews was done and then categories were made and furthermore themes were derived. Results: Our findings revealed that family planning service providers perceived that there is low use of contraceptive methods amongst youth of study area and low usage could be due to side effects; myths and misconceptions; lack of proper knowledge about different contraceptives; unmet needs of contraceptives; socio-cultural and religious factors about different contraceptive methods and family planning service providers own biases against or for use of contraceptive methods amongst youth in the study area. However better education of youth and family planning service providers’ improved knowledge about counseling and use of contraceptive methods was perceived to be associated with improved use of family planning methods amongst youth of the study area. Conclusion: Exaggerated side effects and socio-cultural factors could be important influences leading to low use of family planning methods amongst youth of Karachi. Some policy initiatives are the training of lady health Workers, lady health visitors, physicians and staff of the pharmacies for counseling youth in the correct use of family planning methods. PMID:23618469

77 FR 75865 - Approval and Promulgation of Implementation Plans and Designation of Areas for Air Quality...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-26

... 1997 Annual PM 2.5 NAAQS maintenance plan, including the on-road motor vehicle insignificance finding... Implementation Plan (SIP) to include the 1997 Annual PM 2.5 maintenance plan for the Kentucky portion of the Huntington-Ashland Area. EPA is also approving the on-road motor vehicle insignificance finding for direct PM...

77 FR 35285 - Approval of Air Quality Implementation Plan; Arizona; Attainment Plan for 1997 8-Hour Ozone Standard

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-13

... Quality Implementation Plan; Arizona; Attainment Plan for 1997 8-Hour Ozone Standard AGENCY: U.S... 1997 8-hour ozone national ambient air quality standards (NAAQS) in the Phoenix-Mesa nonattainment area... required for ozone nonattainment areas under title I, part D, subpart 1 of the Clean Air Act (CAA) for the...

77 FR 45954 - Approval and Promulgation of Implementation Plans and Designations of Areas for Air Quality...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-02

...EPA is making two determinations, one regarding the Knoxville, Tennessee, 1997 annual fine particulate (PM2.5) nonattainment area and one regarding the Knoxville-Sevierville-La Follette, Tennessee, 2006 24-hour PM2.5 nonattainment area (both areas have the same geographic boundary and will hereafter be collectively referred to as the ``Knoxville Area'' or ``Area''). First, EPA is determining that the Area has attained the 1997 annual PM2.5 National Ambient Air Quality Standards (NAAQS or ``standard''). Second, EPA is determining that the Area has attained the 2006 24-hour PM2.5 NAAQS. These determinations of attaining data are based upon quality-assured and certified ambient air monitoring data for the 2009-2011 period, showing that the Area has monitored attainment of the 1997 annual PM2.5 NAAQS and 2006 24-hour PM2.5 NAAQS. The requirements for the Area to submit an attainment demonstration and associated reasonably available control measures (RACM), reasonable further progress (RFP) plans, contingency measures, and other planning State Implementation Plan (SIP) revisions related to attainment of the standards shall be suspended so long as the Area continues to attain the respective PM2.5 NAAQS.

The development of rural area residence based on participatory planning case study: A rural residential area of Pucungrejo village, Magelang through "neighborhood development" program

NASA Astrophysics Data System (ADS)

KP, R. M. Bambang Setyohadi; Wicaksono, Dimas

2018-03-01

The poverty is one of the prevailing problems in Indonesia until now. Even a change of the era of governance has not succeeded in eradicating the problem of poverty. The program of poverty alleviation program has always been a focus in the budget allocation in all era of leadership in Indonesia. Those programs were strategic because it prepared the foundation of community self-reliance in the form of representative, entrenched and conducive community leadership institutions to develop of social capital of society in the future. Developing an area of the village requires an integrated planning (Grand Design) to figure out the potential and the problems existing in the rural area as well as the integration of the rural area surrounding. In addition, the grand design needs to be synchronized to the more comprehensive spatial plan with a hierarchical structure such as RTBL, RDTRK / RRTRK, RTRK, and RTRW. This rural area management plan can be oriented or refer to the pattern developed from neighborhood Development program which is part of the PNPM Mandiri program. The neighborhood development program is known as residential area development plan whose process involves of the entire community. Therefore, the regional development up to the scale of the environment requires the planning phase. Particularly, spatial planning which emphasizes the efforts to optimize sectorial development targets to be integrated into an integrated development process must be conducted, in addition to taking into consideration the opportunities, potentials and limitations of the resources, the level of interconnection with the central government within the district and between sub-districts and rural areas.

77 FR 76415 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia; Redesignation of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-28

...EPA is approving a redesignation request and State Implementation Plan (SIP) revision submitted by the State of West Virginia. The West Virginia Department of Environmental Protection (WVDEP) requested that the West Virginia portion of the Huntington- Ashland, WV-KY-OH fine particulate matter (PM2.5) nonattainment area (``Huntington-Ashland Area'' or ``Area'') be redesignated as attainment for the 1997 annual PM2.5 national ambient air quality standard (NAAQS). In this rulemaking action, EPA is approving the 1997 annual PM2.5 redesignation request for the West Virginia portion of the Area. EPA is also approving the maintenance plan SIP revision that the State submitted in conjunction with its redesignation request. The maintenance plan provides for continued attainment of the 1997 annual PM2.5 NAAQS for 10 years after redesignation of the West Virginia portion of the Area. The maintenance plan includes an insignificance determination for the onroad motor vehicle contribution of PM2.5, nitrogen oxides (NOX), and sulfur dioxide (SO2) for the West Virginia portion of the Area for purposes of transportation conformity. EPA is approving West Virginia's insignificance determination for transportation conformity. EPA is also finding that the Area continues to attain the standard. This rulemaking action approving the 1997 annual PM2.5 NAAQS redesignation request, maintenance plan, and insignificance determination for transportation conformity for the West Virginia portion of the Area is based on EPA's determination that the Area has met the criteria for redesignation to attainment specified in the Clean Air Act (CAA).

7 CFR 1948.59 - Ineligible activities.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS... Program § 1948.59 Ineligible activities. (a) Growth management and housing planning grant funds may not be... Governments;” (5) Planning for areas other than approved designated areas; (6) Planning other than growth...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sun, Li-Min, E-mail: limin.sun@yahoo.com; Huang, Chih-Jen; Faculty of Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City, Taiwan

Acute skin reaction during adjuvant radiotherapy for breast cancer is an inevitable process, and its severity is related to the skin dose. A high–skin dose area can be speculated based on the isodose distribution shown on a treatment planning. To determine whether treatment planning can reflect high–skin dose location, 80 patients were collected and their skin doses in different areas were measured using a thermoluminescent dosimeter to locate the highest–skin dose area in each patient. We determined whether the skin dose is consistent with the highest-dose area estimated by the treatment planning of the same patient. The χ{sup 2} andmore » Fisher exact tests revealed that these 2 methods yielded more consistent results when the highest-dose spots were located in the axillary and breast areas but not in the inframammary area. We suggest that skin doses shown on the treatment planning might be a reliable and simple alternative method for estimating the highest skin doses in some areas.« less

36 CFR 292.67 - Operating plan approval-outstanding mineral rights.

Code of Federal Regulations, 2014 CFR

2014-07-01

...-outstanding mineral rights. 292.67 Section 292.67 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL RECREATION AREAS Smith River National Recreation Area Outstanding Mineral Rights § 292.67 Operating plan approval—outstanding mineral rights. (a) Upon receipt of an operating plan...

36 CFR 292.67 - Operating plan approval-outstanding mineral rights.

Code of Federal Regulations, 2012 CFR

2012-07-01

...-outstanding mineral rights. 292.67 Section 292.67 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL RECREATION AREAS Smith River National Recreation Area Outstanding Mineral Rights § 292.67 Operating plan approval—outstanding mineral rights. (a) Upon receipt of an operating plan...

36 CFR 292.67 - Operating plan approval-outstanding mineral rights.

Code of Federal Regulations, 2011 CFR

2011-07-01

...-outstanding mineral rights. 292.67 Section 292.67 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL RECREATION AREAS Smith River National Recreation Area Outstanding Mineral Rights § 292.67 Operating plan approval—outstanding mineral rights. (a) Upon receipt of an operating plan...

36 CFR 292.67 - Operating plan approval-outstanding mineral rights.

Code of Federal Regulations, 2013 CFR

2013-07-01

...-outstanding mineral rights. 292.67 Section 292.67 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL RECREATION AREAS Smith River National Recreation Area Outstanding Mineral Rights § 292.67 Operating plan approval—outstanding mineral rights. (a) Upon receipt of an operating plan...

23 CFR 450.312 - Metropolitan planning area boundaries.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false Metropolitan planning area boundaries. 450.312 Section 450.312 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH... descriptions shall be submitted either as a geo-spatial database or described in sufficient detail to enable...

Cove Area Community Involvement Plan

EPA Pesticide Factsheets

This Community Involvement Plan (CIP) outlines opportunities for individual participation and meaningful information sharing regarding EPA’s activities in the Cove Area Abandoned Uranium Mine Region.

40 CFR 52.1423 - PM10 State implementation plan development in group II areas.

Code of Federal Regulations, 2011 CFR

2011-07-01

... development in group II areas. 52.1423 Section 52.1423 Protection of Environment ENVIRONMENTAL PROTECTION...) Nebraska § 52.1423 PM10 State implementation plan development in group II areas. The state of Nebraska...: (a) An area in the City of Omaha and the area in and around the Village of Weeping Water have been...

40 CFR 52.1423 - PM10 State implementation plan development in group II areas.

Code of Federal Regulations, 2012 CFR

2012-07-01

... development in group II areas. 52.1423 Section 52.1423 Protection of Environment ENVIRONMENTAL PROTECTION...) Nebraska § 52.1423 PM10 State implementation plan development in group II areas. The state of Nebraska...: (a) An area in the City of Omaha and the area in and around the Village of Weeping Water have been...

40 CFR 52.1423 - PM10 State implementation plan development in group II areas.

Code of Federal Regulations, 2013 CFR

2013-07-01

... development in group II areas. 52.1423 Section 52.1423 Protection of Environment ENVIRONMENTAL PROTECTION...) Nebraska § 52.1423 PM10 State implementation plan development in group II areas. The state of Nebraska...: (a) An area in the City of Omaha and the area in and around the Village of Weeping Water have been...

40 CFR 52.1423 - PM10 State implementation plan development in group II areas.

Code of Federal Regulations, 2014 CFR

2014-07-01

... development in group II areas. 52.1423 Section 52.1423 Protection of Environment ENVIRONMENTAL PROTECTION...) Nebraska § 52.1423 PM10 State implementation plan development in group II areas. The state of Nebraska...: (a) An area in the City of Omaha and the area in and around the Village of Weeping Water have been...

Space science to the twenty-first century and the technological implications for implementation

NASA Technical Reports Server (NTRS)

Herman, D. H.

1979-01-01

The paper presents the specific plan for NASA space science missions to the 21st century and highlights the major technological advances that must be effected to accomplish the planned missions. Separate consideration is given to plans for astrophysics, planetary exploration, the solar terrestrial area, and life sciences. The technological consequences of the plans in these separate areas are discussed.

New deglacial and Holocene micropaleontological and geochemical records from the southern margin of the Svalbard Archipelago (Arctic Ocean)

NASA Astrophysics Data System (ADS)

Rigual-Hernández, Andrés.

2010-05-01

This study is presented in the context of the Spanish research project "The development of an Arctic ice stream-dominated sedimentary system: The southern Svalbard continental margin" (SVAIS), developed within the framework of the International Polar Year (IPY) Activity N. 367 (NICE STREAMS). Its main goal is to understand the evolution of glacial continental margins and their relationship with the changes in ice sheet dynamics induced by natural climatic changes, combining the geophysical data with the sediment record both collected during an oceanographic cruise in the Storfjorden area (SW Svalbard margin) in August 2007. This marine depositional system, dominated by an ice stream during the last glacial period, was selected due to its small size inducing a rapid response to climatic changes, and for the oceanographic relevance of the area for global ocean circulation. The results obtained aim to define the sedimentary architecture and morphology, and to provide more insight into the paleoceanographic and paleoclimatic evolution of the region. We specifically report on new micropaleontological and geochemical data obtained from the sediment cores. A preliminary age model indicates that the sediment sequences cover approximately the Last Deglaciation and the Holocene. Microfossils are generally well preserved, although the abundances of the different groups show marked shifts along the record. Low concentrations of coccolithophores, diatoms, planktic foraminifers and cysts of organic-walled dinoflagellates (dinocysts) are found at the lower half of the sequence (IRD-rich, coarser-grained sediments), and increase towards the Late Holocene (fine-grained bioturbated sediments). The Climatic Optimum is characterized by the warmest sea surface temperatures as estimated from the fossil assemblage, diverse transfer functions and biogeochemical proxies, and by high nutrient contents in the bottom waters shown by light carbon isotope values and high Cd/Ca ratios in benthic foraminifers. Dilution by terrigenous material, related to the retreat of the Barents Sea Ice Sheet in response to changes in the strength of the Atlantic-sourced, warm Western Spitsbergen Current, seems to be important in driving the abundances of microfossils and of organic compounds. The different stages of the Deglaciation and the Holocene and the associated modifications in the surface oceanic environment are documented by changes in the fossil assemblage composition of the different microfossil groups, while synchronous changes in the bottom water masses are registered by stable isotope and trace element analyses of benthic foraminifers.

Lunar map showing traverse plans for Apollo 14 lunar landing mission

NASA Image and Video Library

1970-09-01

This lunar map shows the traverse plans for the Apollo 14 lunar landing mission. Areas marked include Lunar module landing site, areas for the Apollo Lunar Surface Experiment Package (ALSEP) and areas for gathering of core samples.

78 FR 78266 - Approval and Promulgation of Implementation Plans; North Carolina; Transportation Conformity...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-26

... one year after the effective date of the nonattainment area (NAA) designations. See Section 40 CFR 51... \\1\\ currently applies to areas that are designated nonattainment and to areas that have been redesignated to attainment after 1990 (maintenance areas) with plans developed under section 175A of the Act...

77 FR 60319 - Harbor Porpoise Take Reduction Plan; Coastal Gulf of Maine Closure Area Established With a...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-03

...-XC099 Harbor Porpoise Take Reduction Plan; Coastal Gulf of Maine Closure Area Established With a... Atmospheric Administration (NOAA), Commerce. ACTION: Establishment of the Coastal Gulf of Maine Closure Area... Service (NMFS) announces the establishment of the Coastal Gulf of Maine Closure Area under the Harbor...

40 CFR 52.823 - PM10 State Implementation Plan Development in Group II Areas.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Development in Group II Areas. 52.823 Section 52.823 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... State Implementation Plan Development in Group II Areas. The Iowa Department of Natural Resources...: Three groups within the State of Iowa have been classified as Group II areas for fine particulate (PM-10...

40 CFR 52.823 - PM10 State Implementation Plan Development in Group II Areas.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Development in Group II Areas. 52.823 Section 52.823 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... State Implementation Plan Development in Group II Areas. The Iowa Department of Natural Resources...: Three groups within the State of Iowa have been classified as Group II areas for fine particulate (PM-10...

40 CFR 52.823 - PM10 State Implementation Plan Development in Group II Areas.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Development in Group II Areas. 52.823 Section 52.823 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... State Implementation Plan Development in Group II Areas. The Iowa Department of Natural Resources...: Three groups within the State of Iowa have been classified as Group II areas for fine particulate (PM-10...

40 CFR 52.823 - PM10 State Implementation Plan Development in Group II Areas.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Development in Group II Areas. 52.823 Section 52.823 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... State Implementation Plan Development in Group II Areas. The Iowa Department of Natural Resources...: Three groups within the State of Iowa have been classified as Group II areas for fine particulate (PM-10...

40 CFR 52.823 - PM10 State Implementation Plan Development in Group II Areas.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Development in Group II Areas. 52.823 Section 52.823 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... State Implementation Plan Development in Group II Areas. The Iowa Department of Natural Resources...: Three groups within the State of Iowa have been classified as Group II areas for fine particulate (PM-10...

The Federal Aviation Administration Plan for Research, Engineering and Development. Volume 2. Project Descriptions

DTIC Science & Technology

1989-01-01

managerial areas , including: management and control of the operational requirements of the NAS F& E Plan; preparation, management, and control of the annual... areas (capacity, safety, security, and efficiency), highlights of key programs, and a discussion of the relationships of the RE&D Plan to the NAS F& E ...release of SUA , such as restricted airspace and military operations areas , are currently limited by several factors, including manual interagency

Loads and Aeroelasticity Division research and technology accomplishments for FY 1984 and plans for FY 1985

NASA Technical Reports Server (NTRS)

Gardner, J. E.; Dixon, S. C.

1985-01-01

The loads and aeroelasticity divisions research accomplishments are presented. The work under each branch or technical area, described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to 5 year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

Quality Assurance Project Plan for Closure of the Central Facilities Area Sewage Treatment Plant Lagoon 3 and Land Application Area

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lewis, Michael G.

This quality assurance project plan describes the technical requirements and quality assurance activities of the environmental data collection/analyses operations to close Central Facilities Area Sewage treatment Plant Lagoon 3 and the land application area. It describes the organization and persons involved, the data quality objectives, the analytical procedures, and the specific quality control measures to be employed. All quality assurance project plan activities are implemented to determine whether the results of the sampling and monitoring performed are of the right type, quantity, and quality to satisfy the requirements for closing Lagoon 3 and the land application area.

Career Planning Support System Program (CPSS). Final Report.

ERIC Educational Resources Information Center

Ohio State Univ., Columbus. National Center for Research in Vocational Education.

Intended for the developmental practitioner, this report examines literature produced by the Career Planning Support System dealing with career guidance in four major areas: minority youth; women; transition from school to work; and program planning and evaluation. The area of minority youth includes a review of literature on: educational and…

77 FR 24399 - Approval and Promulgation of Implementation Plans; Georgia; Atlanta; Ozone 2002 Base Year...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-24

... Promulgation of Implementation Plans; Georgia; Atlanta; Ozone 2002 Base Year Emissions Inventory AGENCY... approve the ozone 2002 base year emissions inventory, portion of the state implementation plan (SIP... Atlanta, Georgia (hereafter referred to as ``the Atlanta Area'' or ``Area''), ozone attainment...

Field test designs for the evaluation of vessel operators' use of and confidence in various aids to navigation

DOT National Transportation Integrated Search

1995-12-01

Development Center in evaluating current Coast Guard policies and development plans for : Waterways Management, a "Waterways Management Research and Planning" task plan was : established as Task Area A in FY '94. The purpose of this task area is to d...

40 CFR 300.210 - Federal contingency plans.

Code of Federal Regulations, 2010 CFR

2010-07-01

... contingency plans under the national response system: The National Contingency Plan, RCPs, and ACPs. These... discharge under § 300.324, and to mitigate or prevent a substantial threat of such a discharge, from a vessel, offshore facility, or onshore facility operating in or near the area. (2) The areas of...

36 CFR 292.64 - Plan of operations-approval.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false Plan of operations-approval. 292.64 Section 292.64 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL RECREATION AREAS Smith River National Recreation Area Locatable Minerals § 292.64 Plan of...

36 CFR 292.64 - Plan of operations-approval.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 36 Parks, Forests, and Public Property 2 2013-07-01 2013-07-01 false Plan of operations-approval. 292.64 Section 292.64 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL RECREATION AREAS Smith River National Recreation Area Locatable Minerals § 292.64 Plan of...

36 CFR 292.64 - Plan of operations-approval.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false Plan of operations-approval. 292.64 Section 292.64 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL RECREATION AREAS Smith River National Recreation Area Locatable Minerals § 292.64 Plan of...

36 CFR 292.64 - Plan of operations-approval.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false Plan of operations-approval. 292.64 Section 292.64 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL RECREATION AREAS Smith River National Recreation Area Locatable Minerals § 292.64 Plan of...

78 FR 35957 - Notice of Intent To Prepare a Resource Management Plan for the Central Yukon Planning Area Alaska...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-14

... Rivers system; management of wilderness characteristics; protection of resources important to maintaining a subsistence lifestyle; the importance of subsistence to local economies and traditional lifestyles... BLM-managed lands in the planning area for wilderness characteristics using criteria established by...

Tourism and recreation system planning in Alberta provincial parks

Treesearch

Paul F.J. Eagles; Angela M. Gilmore; Luis X. Huang; Denise A. Keltie; Kimberley Rae; Hong Sun; Amy K. Thede; Meagan L. Wilson; Jennifer A. Woronuk; Ge Yujin

2007-01-01

Traditionally, system planning in parks and protected areas concentrated on biogeographical concepts, while neglecting tourism and recreation. The existing system plan for parks and protected areas in Alberta, Canada, divides the province into six natural regions based on a geographic classifi cation system (Grassland, Parkland, Foothills, Rocky Mountains, Boreal...

12 CFR 563e.27 - Strategic plan.

Code of Federal Regulations, 2012 CFR

2012-01-01

... been designated as a wholesale or limited purpose savings association, shall emphasize lending and... savings association's record of helping to meet the credit needs of its assessment area(s) under a strategic plan if: (1) The savings association has submitted the plan to the OTS as provided for in this...

12 CFR 563e.27 - Strategic plan.

Code of Federal Regulations, 2014 CFR

2014-01-01

... been designated as a wholesale or limited purpose savings association, shall emphasize lending and... savings association's record of helping to meet the credit needs of its assessment area(s) under a strategic plan if: (1) The savings association has submitted the plan to the OTS as provided for in this...

12 CFR 563e.27 - Strategic plan.

Code of Federal Regulations, 2013 CFR

2013-01-01

... been designated as a wholesale or limited purpose savings association, shall emphasize lending and... savings association's record of helping to meet the credit needs of its assessment area(s) under a strategic plan if: (1) The savings association has submitted the plan to the OTS as provided for in this...

36 CFR 292.64 - Plan of operations-approval.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Plan of operations-approval. 292.64 Section 292.64 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL RECREATION AREAS Smith River National Recreation Area Locatable Minerals § 292.64 Plan of...

75 FR 54177 - Notice of Availability of the Draft Jarbidge Field Office Resource Management Plan and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-03

... throughout the planning area. Alternative III focuses on restoring the resiliency of ecosystem structure and... planning area. Alternative IV focuses on actively restoring the resiliency of ecosystem structure and... Development. Sand Point ACEC (950 acres) Relevant and Important Values: Cultural, Geologic, Historic...

7 CFR 1948.82 - Plan and State Investment Strategy approval procedure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 13 2010-01-01 2009-01-01 true Plan and State Investment Strategy approval procedure... Impacted Area Development Assistance Program § 1948.82 Plan and State Investment Strategy approval... the State Investment Strategy for Energy Impacted Areas. (c) Appropriate growth management and/or...

Lake Mead National Recreational Area air tour management plan and planning and National Environmental Policy Act scoping document

DOT National Transportation Integrated Search

2004-04-19

The Federal Aviation Administration (FAA), in cooperation with the National Park Service (NPS), has initiated the development of an Air Tour Management Plan (ATMP) for Lake Mead National Recreation Area (LAME) pursuant to the National Parks Air Tour ...

77 FR 38779 - Notice of Availability of Draft Environmental Impact Statement for the Proposed Mather Specific...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-29

... Environmental Impact Statement for the Proposed Mather Specific Plan Project, Sacramento County, CA, Corps...-acre Mather Specific Plan area, Sacramento County, California (note that approximately 2,554 acres of the Plan area contains existing development, primarily Mather Airport, a Commerce Center, a...

78 FR 47410 - General Management Plan, Draft Environmental Impact Statement, Gateway National Recreation Area...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-05

...] General Management Plan, Draft Environmental Impact Statement, Gateway National Recreation Area, New... (NPS) is releasing a Draft Environmental Impact Statement (DEIS) for the General Management Plan (GMP... alternatives to guide the management of the site over the next 20 years. The NPS preferred alternative...

Planning for New Primary Airports in the United States: A Survey of Metropolitan Planning Organizations

NASA Technical Reports Server (NTRS)

NewMyer, David A.

1999-01-01

Airport congestion at primary airports in major metropolitan areas was analyzed in a report prepared by the Transportation Research Board (TRB) in 1990. Taking the top twenty-three most congested airports from this study, a questionnaire was prepared and sent to the metropolitan planning organizations (MPOs) for twenty of the twenty-three metropolitan areas represented in the TRB study, The questionnaire focused on the role of the MPOs in planning for new primary airports in the United States, including questions about the status of the most recent MPO airport system plan, whether or not the latest plan recommends a new primary airport, and whether or not any other entities in the MPO areas are recommending new primary airports. The results indicated that 44.4 percent of the eighteen respondent MPOs have airport system plans that are five years old or older. Also, only two of the respondent MPOs have recommended a new primary airport in their latest regional airport system plan and only one of these two is a common recommendation in the Federal Aviation Administration's National Plan of Integrated Airport System.

Planning for New Primary Airports in the United States: A Survey of Metropolitan Planning Organizations

NASA Technical Reports Server (NTRS)

NewMeyer, David A.

1999-01-01

Airport congestion at primary airports in major metropolitan areas was analyzed in a report prepared by the Transportation Research Board (TRB) in 1990. Taking the top twenty-three most congested airports from this study, a questionnaire was prepared and sent to the metropolitan planning organizations (MPOS) for twenty of the twenty-three metropolitan areas represented in the TRB study. The questionnaire focused on the role of the MPOs in planning for new primary airports in the United States, including questions about the status of the most recent MPO airport system plan, whether or not the latest plan recommends a new primary airport, and whether or not any other entities in the MPO areas are recommending new primary airports. The results indicated that 44.4 percent of the eighteen respondent MPOs have airport system plans that are five years old or older. Also, only two of the respondent MPOs have recommended a new primary airport in their latest regional airport system plan and only one of these two is a common recommendation in the Federal Aviation Administration's National Plan of Integrated Airport System.

33 CFR 103.520 - Recordkeeping.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 103.520 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MARITIME SECURITY MARITIME SECURITY: AREA MARITIME SECURITY Area Maritime Security (AMS) Plan § 103.520 Recordkeeping. (a) All records pertaining to the Area Maritime Security (AMS) Assessment and AMS Plan will be retained by...

48 CFR 1819.7102 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS NASA Rural Area Small Business Plan 1819.7102 General. Pursuant to Public Law 100-590, NASA established a Rural Area Business Enterprise Development Plan, including methods for encouraging prime and subcontractors to use small business concerns located in rural areas as...

78 FR 44494 - Approval and Promulgation of Implementation Plans; Designation of Areas for Air Quality Planning...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-24

...EPA is proposing to approve, as a revision of the California state implementation plan, the State's request to redesignate the Sacramento nonattainment area to attainment for the 24-hour particulate matter of ten microns or less (PM10) National Ambient Air Quality Standard (NAAQS). EPA is also proposing to approve the PM10 maintenance plan and the associated motor vehicle emissions budgets for use in transportation conformity determinations necessary for the Sacramento area. Finally, EPA is proposing to approve the attainment year emissions inventory. EPA is proposing these actions because the SIP revision meets the requirements of the Clean Air Act and EPA guidance for such plans and motor vehicle emissions budgets.

30 CFR 219.417 - How will MMS disburse qualified OCS revenues to the coastal political subdivisions if, during any...

Code of Federal Regulations, 2010 CFR

2010-07-01

... in the 181 Area in the Eastern Gulf of Mexico Planning Area? 219.417 Section 219.417 Mineral... no applicable leased tracts in the 181 Area in the Eastern Gulf of Mexico Planning Area? If, during any fiscal year, there are no applicable leased tracts in the 181 Area in the Eastern Gulf of Mexico...

Affirmative Action Plans, January 1, 1994--December 31, 1994. Revision

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-02-16

This document is the Affirmative Action Plan for January 1, 1994 through December 31, 1994 for the Lawrence Berkeley Laboratory, University of California (``LBL`` or ``the Laboratory.``) This is an official document that will be presented upon request to the Office of Federal Contract Compliance Programs, US Department of Labor. The plan is prepared in accordance with the Executive Order 11246 and 41 CFR Section 60-1 et seq. covering equal employment opportunity and will be updated during the year, if appropriate. Analyses included in this volume as required by government regulations are based on statistical comparisons. All statistical comparisons involvemore » the use of geographic areas and various sources of statistics. The geographic areas and sources of statistics used here are in compliance with the government regulations, as interpreted. The use of any geographic area or statistic does not indicate agreement that the geographic area is the most appropriate or that the statistic is the most relevant. The use of such geographic areas and statistics is intended to have no significance outside the context of this Affirmative Action Plan, although, of course, such statistics and geographic areas will be used in good faith with respect to this Affirmative Action Plan.« less

Field Implementation Plan for the In-Situ Bioremediation Treatability Study at the Technical Area-V Groundwater Area of Concern

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Jun

This Field Implementation Plan (FIP) was prepared by Sandia National Laboratories, New Mexico (SNL/NM) and provides instruction on conducting a series of in-situ bioremediation (ISB) tests as described in the Revised Treatability Study Work Plan for In-Situ Bioremediation at the Technical Area-V Groundwater Area of Concern, referred to as the Revised Work Plan in this FIP. The Treatability Study is designed to gravity inject an electron-donor substrate and bioaugmentation bacteria into groundwater via three injection wells to perform bioremediation of the constituents of concern (COCs), nitrate and trichloroethene (TCE), in the regions with the highest concentrations at the Technical Area-Vmore » Groundwater (TAVG) Area of Concern (AOC). The Treatability Study will evaluate the effectiveness of bioremediation solution delivery and COC treatment over time. This FIP is designed for SNL/NM work planning and management. It is not intended to be submitted for regulator’s approval. The technical details presented in this FIP are subject to change based on field conditions, availability of equipment and materials, feasibility, and inputs from Sandia personnel and Aboveground Injection System contractor.« less

Market characteristics and awareness of managed care options among elderly beneficiaries enrolled in traditional Medicare.

PubMed

Mittler, Jessica N; Landon, Bruce E; Zaslavsky, Alan M; Cleary, Paul D

2011-10-14

Medicare beneficiaries' awareness of Medicare managed care plans is critical for realizing the potential benefits of coverage choices. To assess the relationships of the number of Medicare risk plans, managed care penetration, and stability of plans in an area with traditional Medicare beneficiaries' awareness of the program. Cross-sectional analysis of Medicare Current Beneficiary Survey data about beneficiaries' awareness and knowledge of Medicare managed care plan availability. Logistic regression models used to assess the relationships between awareness and market characteristics. Traditional Medicare beneficiaries (n = 3,597) who had never been enrolled in Medicare managed care, but had at least one plan available in their area in 2002, and excluding beneficiaries under 65, receiving Medicaid, or with end stage renal disease. Traditional Medicare beneficiaries' knowledge of Medicare managed care plans in general and in their area. Having more Medicare risk plans available was significantly associated with greater awareness, and having an intermediate number of plans (2-4) was significantly associated with more accurate knowledge of Medicare risk plan availability than was having fewer or more plans. Medicare may have more success engaging consumers in choice and capturing the benefits of plan competition by more actively selecting and managing the plan choice set. Public Domain.

Market Characteristics and Awareness of Managed Care Options Among Elderly Beneficiaries Enrolled in Traditional Medicare

PubMed Central

Mittler, Jessica N.; Landon, Bruce E.; Zaslavsky, Alan M.; Cleary, Paul D.

2011-01-01

Background Medicare beneficiaries' awareness of Medicare managed care plans is critical for realizing the potential benefits of coverage choices. Objectives To assess the relationships of the number of Medicare risk plans, managed care penetration, and stability of plans in an area with traditional Medicare beneficiaries' awareness of the program. Research Design Cross-sectional analysis of Medicare Current Beneficiary Survey data about beneficiaries' awareness and knowledge of Medicare managed care plan availability. Logistic regression models used to assess the relationships between awareness and market characteristics. Subjects Traditional Medicare beneficiaries (n = 3,597) who had never been enrolled in Medicare managed care, but had at least one plan available in their area in 2002, and excluding beneficiaries under 65, receiving Medicaid, or with end stage renal disease. Measures Traditional Medicare beneficiaries' knowledge of Medicare managed care plans in general and in their area. Results Having more Medicare risk plans available was significantly associated with greater awareness, and having an intermediate number of plans (2-4) was significantly associated with more accurate knowledge of Medicare risk plan availability than was having fewer or more plans. Conclusions Medicare may have more success engaging consumers in choice and capturing the benefits of plan competition by more actively selecting and managing the plan choice set. PMID:22340776

14 CFR 77.75 - Establishment of antenna farm areas.

Code of Federal Regulations, 2011 CFR

2011-01-01

... indicated on an FAA planning document or military service military airport planning document. Planned or...; any other FAA planning document, or military service military airport planning document. Public use... layout plan, a military service approved military airport layout plan, or by any planning document...

Ecology of Greater Sage-Grouse in the Bi-State Planning Area Final Report, September 2007

USGS Publications Warehouse

Casazza, Michael L.; Overton, Cory T.; Farinha, Melissa A.; Torregrosa, Alicia; Fleskes, Joseph P.; Miller, Michael R.; Sedinger, James S.; Kolada, Eric J.

2009-01-01

Conservation efforts for greater sage-grouse (Centrocercus urophasianus), hereafter sage-grouse, are underway across the range of this species. Over 70 local working groups have been established and are implementing on-the-ground sage-grouse oriented conservation projects. Early on in this process, the California Department of Fish and Game (CDFG) recognized the need to join in these efforts and received funding from the U.S. Fish and Wildlife Service (USFWS) under the Candidate Species Conservation Program to help develop a species conservation plan for sage-grouse in the Mono County area. This conservation plan covers portions of Alpine, Mono, and Inyo counties in California and Douglas, Esmeralda, Lyon, and Mineral counties in Nevada. A concurrent effort underway through the Nevada Governor's Sage-grouse Conservation Team established Local Area Working Groups across Nevada and eastern California. The Mono County populations of sage-grouse were encompassed by the Bi-State Local Planning Area, which was comprised of six population management units (PMUs). The state agencies from California (CDFG) and Nevada (Nevada Department of Wildlife; NDOW) responsible for the management of sage-grouse agreed to utilize the process that had begun with the Nevada Governor's Team in order to develop local plans for conservation planning and implementation. Resources from the USFWS were applied to several objectives in support of the development of the Bi-State Local Area Sage-grouse Conservation Plan through a grant to the U.S. Geological Survey (USGS). Objectives included: (1) participate in the development of the Bi-State Conservation Plan, (2) compile and synthesize existing sage-grouse data, (3) document seasonal movements of sage-grouse, (4) identify habitats critical to sage-grouse, (5) determine survival rates and identify causal factors of mortality, (6) determine nest success and brood success of sage-grouse, and (7) identify sage-grouse lek sites. Progress reports completed in 2004 and 2005 addressed each of the specific objectives and this final report focuses on the biological information gathered in support of local conservation efforts. Participation in the development of the Bi-State Local Area Conservation Plan was accomplished on multiple scales. Beginning in the fall of 2002, USGS personnel began participating in meetings of local stakeholders involved in the development of a sage-grouse conservation plan for the Bi-State planning area. This included attendance at numerous local PMU group meetings and field trips as well as participating on the technical advisory committee (TAC) for the Bi-State group. Whenever appropriate, ongoing results and findings regarding sage-grouse ecology in the local area were incorporated into these working group meetings. In addition, the USGS partnered with CDFG to help reorganize one of the local PMU groups (South Mono) and edited that portion of the Bi-State plan. The USGS also worked closely with CDFG to draft a description of the state of knowledge for sage-grouse genetic information for inclusion in the Bi-State Conservation Plan. The first edition of the Bi-State Conservation Plan for Greater Sage-Grouse was completed in June 2004 (Bi-State Sage-grouse Conservation Team 2004). This report is organized primarily by PMU to facilitate the incorporation of these research findings into the individual PMU plans that compose the Bi-State plan. Information presented in this report was derived from over 7,000 radio-telemetry locations obtained on 145 individual sage-grouse during a three year period (2003-2005). In addition, we collected detailed vegetation measurements at over 590 habitat sampling plots within the study area including canopy cover, shrubs, forbs, and grasses diversity. Vegetation data collection focused on sage-grouse nests, and brood-use areas. Additionally we collected data at random sites to examine sage-grouse habitat relationships within the study area. The majori

Closure Plan for the Area 5 Radioactive Waste Management Site at the Nevada Test Site

DOE Office of Scientific and Technical Information (OSTI.GOV)

NSTec Environmental Management

The Area 5 Radioactive Waste Management Site (RMWS) at the Nevada Test Site (NTS) is managed and operated by National Security Technologies, LLC (NSTec), for the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office (NNSA/NSO). This document is the first update of the preliminary closure plan for the Area 5 RWMS at the NTS that was presented in the Integrated Closure and Monitoring Plan (DOE, 2005a). The major updates to the plan include a new closure schedule, updated closure inventory, updated site and facility characterization data, the Title II engineering cover design, and the closure processmore » for the 92-Acre Area of the RWMS. The format and content of this site-specific plan follows the Format and Content Guide for U.S. Department of Energy Low-Level Waste Disposal Facility Closure Plans (DOE, 1999a). This interim closure plan meets closure and post-closure monitoring requirements of the order DOE O 435.1, manual DOE M 435.1-1, Title 40 Code of Federal Regulations (CFR) Part 191, 40 CFR 265, Nevada Administrative Code (NAC) 444.743, and Resource Conservation and Recovery Act (RCRA) requirements as incorporated into NAC 444.8632. The Area 5 RWMS accepts primarily packaged low-level waste (LLW), low-level mixed waste (LLMW), and asbestiform low-level waste (ALLW) for disposal in excavated disposal cells.« less

The study on changes of rectum area in proton prostate cancer therapy

NASA Astrophysics Data System (ADS)

Kim, S. Y.; Lee, H. K.; Shin, H. W.; Kim, S. C.; Cho, J. H.

2015-10-01

The purpose of this study is to determine the changes in the rectum area during treatment and to identify the rectum area within the given field of view in order to reproduce the same pose as that presented during therapy planning to properly deliver the planned dose to the prostate. We obtained digitally reconstructed radiographs after planning treatment for 30 patients out of all patients who had been subjected to proton prostate cancer therapy from August 2012 to November 2014 at this hospital. We then obtained an image using a digital imaging positioning system (DIPS) on the first day of treatment. When planning the digitally reconstructed radiograph treatment, we determined the change in size of the rectum between the actual treatment and treatment planning by measuring the cross section of the rectum and the cross section on the image from the DIPS. The results indicated that the rectum area in the digitally reconstructed radiograph taken during treatment planning and the rectum area obtained from the DIPS image during treatment were different. As a consequence, when region targeted for proton treatment of prostate cancer does not maintain a constant volume, the position of the prostate does not receive an adequate dose due to such changes. Therefore, the results of this study will be useful to determine the corresponding volume during a prostate treatment plan.

40 CFR 51.902 - Which classification and nonattainment area planning provisions of the CAA shall apply to areas...

Code of Federal Regulations, 2011 CFR

2011-07-01

... area planning provisions of the CAA shall apply to areas designated nonattainment for the 8-hour NAAQS? 51.902 Section 51.902 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Implementation of 8-hour Ozone National Ambient Air Quality Standard § 51.902 Which classification and...

40 CFR 51.902 - Which classification and nonattainment area planning provisions of the CAA shall apply to areas...

Code of Federal Regulations, 2014 CFR

2014-07-01

... area planning provisions of the CAA shall apply to areas designated nonattainment for the 1997 8-hour NAAQS? 51.902 Section 51.902 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Implementation of 8-hour Ozone National Ambient Air Quality Standard § 51.902 Which classification and...

40 CFR 51.902 - Which classification and nonattainment area planning provisions of the CAA shall apply to areas...

Code of Federal Regulations, 2012 CFR

2012-07-01

... area planning provisions of the CAA shall apply to areas designated nonattainment for the 1997 8-hour NAAQS? 51.902 Section 51.902 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Implementation of 8-hour Ozone National Ambient Air Quality Standard § 51.902 Which classification and...

40 CFR 51.902 - Which classification and nonattainment area planning provisions of the CAA shall apply to areas...

Code of Federal Regulations, 2013 CFR

2013-07-01

... area planning provisions of the CAA shall apply to areas designated nonattainment for the 1997 8-hour NAAQS? 51.902 Section 51.902 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Implementation of 8-hour Ozone National Ambient Air Quality Standard § 51.902 Which classification and...

40 CFR 51.902 - Which classification and nonattainment area planning provisions of the CAA shall apply to areas...

Code of Federal Regulations, 2010 CFR

2010-07-01

... area planning provisions of the CAA shall apply to areas designated nonattainment for the 8-hour NAAQS? 51.902 Section 51.902 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Implementation of 8-hour Ozone National Ambient Air Quality Standard § 51.902 Which classification and...

Thermal area effectiveness for future aircraft

NASA Technical Reports Server (NTRS)

Happ, W. W.

1975-01-01

Problem areas in airport planning, design, and operations identified by a decision matrix developed to display various airport functions interfaced with facilities and an extensive literature survey were investigated. Areas considered include: site selection and growth potential; emissions and noise control/containment for airports; financial and legal aspects of airport planning, contruction, and operation; intra-airport transportation and other passenger flow facilitators; simulation and modeling for airports; guidelines for airport multimodal access planning. Results are summarized and a bibliography is included.

76 FR 15219 - Approval and Promulgation of Implementation Plans; Designation of Areas for Air Quality Planning...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-21

... of the San Joaquin Valley Air Basin and East Kern areas for particulate matter of ten microns or less... for particulate matter of ten microns or less (PM-10) by splitting the area into two separate...

Stormwater Pollution Prevention Plan TA-60 Roads and Grounds Facility and Associated Sigma Mesa Staging Area

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sandoval, Leonard Frank

This Stormwater Pollution Prevention Plan (SWPPP) is applicable to operations at the Technical Area -60 (TA-60) Roads and Grounds Facility and Associated Sigma Mesa Staging Area off Eniwetok Drive, in Los Alamos County, New Mexico.

Assessing climate change-robustness of protected area management plans-The case of Germany.

PubMed

Geyer, Juliane; Kreft, Stefan; Jeltsch, Florian; Ibisch, Pierre L

2017-01-01

Protected areas are arguably the most important instrument of biodiversity conservation. To keep them fit under climate change, their management needs to be adapted to address related direct and indirect changes. In our study we focus on the adaptation of conservation management planning, evaluating management plans of 60 protected areas throughout Germany with regard to their climate change-robustness. First, climate change-robust conservation management was defined using 11 principles and 44 criteria, which followed an approach similar to sustainability standards. We then evaluated the performance of individual management plans concerning the climate change-robustness framework. We found that climate change-robustness of protected areas hardly exceeded 50 percent of the potential performance, with most plans ranking in the lower quarter. Most Natura 2000 protected areas, established under conservation legislation of the European Union, belong to the sites with especially poor performance, with lower values in smaller areas. In general, the individual principles showed very different rates of accordance with our principles, but similarly low intensity. Principles with generally higher performance values included holistic knowledge management, public accountability and acceptance as well as systemic and strategic coherence. Deficiencies were connected to dealing with the future and uncertainty. Lastly, we recommended the presented principles and criteria as essential guideposts that can be used as a checklist for working towards more climate change-robust planning.

Personal Financial Planning: Failure to Plan Properly May Have Dire Consequences.

ERIC Educational Resources Information Center

Rosenbloom, Jerry

1988-01-01

Effective personal financial planning results in sound decisions in the areas of insurance, accumulating capital, retirement planning, and tax planning. Appropriate financial planning concerns everyone--regardless of his or her stage in life. (MLW)

15 CFR 921.13 - Management plan and environmental impact statement development.

Code of Federal Regulations, 2011 CFR

2011-01-01

... submitted pursuant to § 921.12, the state may begin draft management plan development and the collection of information necessary for the preparation by NOAA of an EIS. The state shall develop a draft management plan... areas of the Reserve, ranking these areas according to their relative importance, and including a...

42 CFR 422.111 - Disclosure requirements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... information specified in paragraph (b) of this section— (1) To each enrollee electing an MA plan it offers; (2... description must include the following information: (1) Service area. The MA plan's service area and any... an MA-PD plan, the information in § 423.128 of this chapter; and for purposes of comparison- (i) The...

47 CFR 11.21 - State and Local Area plans and FCC Mapbook.

Code of Federal Regulations, 2013 CFR

2013-10-01

... distribution such as the use of the Radio Broadcast Data System (RBDS). The plans must be reviewed and approved... Plans should include a data table, in computer readable form, clearly showing monitoring assignments and.... It organizes all broadcast stations and cable systems according to their State, EAS Local Area, and...

47 CFR 11.21 - State and Local Area plans and FCC Mapbook.

Code of Federal Regulations, 2011 CFR

2011-10-01

... distribution such as the use of the Radio Broadcast Data System (RBDS). The plans must be reviewed and approved... Participants. State EAS plans should include a data table, in computer readable form, clearly showing.... It organizes all broadcast stations and cable systems according to their State, EAS Local Area, and...

47 CFR 11.21 - State and Local Area plans and FCC Mapbook.

Code of Federal Regulations, 2010 CFR

2010-10-01

... distribution such as the use of the Radio Broadcast Data System (RBDS). The plans must be reviewed and approved... Participants. State EAS plans should include a data table, in computer readable form, clearly showing.... It organizes all broadcast stations and cable systems according to their State, EAS Local Area, and...

47 CFR 11.21 - State and Local Area plans and FCC Mapbook.

Code of Federal Regulations, 2012 CFR

2012-10-01

... distribution such as the use of the Radio Broadcast Data System (RBDS). The plans must be reviewed and approved... Plans should include a data table, in computer readable form, clearly showing monitoring assignments and.... It organizes all broadcast stations and cable systems according to their State, EAS Local Area, and...

47 CFR 11.21 - State and Local Area plans and FCC Mapbook.

Code of Federal Regulations, 2014 CFR

2014-10-01

... distribution such as the use of the Radio Broadcast Data System (RBDS). The plans must be reviewed and approved... Plans should include a data table, in computer readable form, clearly showing monitoring assignments and.... It organizes all broadcast stations and cable systems according to their State, EAS Local Area, and...

Preparing for High Technology: 30 Steps to Implementation. Research & Development Series No. 232.

ERIC Educational Resources Information Center

Abram, Robert; And Others

This planning guide is one of three that addresses the concerns of postsecondary college administrators and planners regarding the planning and implementation of technician training programs in high technology areas. It specifically focuses on a 30-step planning process that is generalizable to various high technology areas. (The other two…

Master Planning Guide for Instructional Objectives. Colorado State Plan for the Developmentally Disabled.

ERIC Educational Resources Information Center

Myers, Marvin L.; And Others

Presented by the Master Planning Committee of the Colorado Department of Institutions and the Division of Developmental Disabilities is a behavior inventory of sequential skills in four areas basic to the normalization of developmentally disabled persons. Instructional objectives are listed in the following areas: physical, including perceptual…

Area health education center libraries and medical school libraries: establishing an interface.

PubMed Central

Bandy, C R

1978-01-01

Establishing an interface between area health education center (AHEC) libraries and medical school libraries requires careful planning, including: the overall plan, needs assessment, resource evaluation, a developmental plan, monitoring and evaluation, institutional agreements, and publicity. This paper reports on the development of AHEC libraries in North Dakota. PMID:708958

49 CFR 194.107 - General response plan requirements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... management system including the functional areas of finance, logistics, operations, planning, and command... economically sensitive areas; (iii) Describe the responsibilities of the operator and of Federal, State and...

5. METAL SHOP ROOM (AREA 108 ON PLAN CA236R36). Looking ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. METAL SHOP ROOM (AREA 108 ON PLAN CA-236-R-36). Looking northeast. - Edwards Air Force Base, Air Force Rocket Propulsion Laboratory, Test Stand 1-A Terminal Room, Test Area 1-120, north end of Jupiter Boulevard, Boron, Kern County, CA

Waste Encapsulation and Storage Facility (WESF) Dangerous Waste Training Plan (DWTP)

DOE Office of Scientific and Technical Information (OSTI.GOV)

SIMMONS, F.M.

2000-03-29

This Waste Encapsulation Storage Facility (WESF) Dangerous Waste Training Plan (DWTP) applies to personnel who perform work at, or in support of WESF. The plan, along with the names of personnel, may be given to a regulatory agency inspector upon request. General workers, subcontractors, or visiting personnel who have not been trained in the management of dangerous wastes must be accompanied by an individual who meets the requirements of this training plan. Dangerous waste management includes handling, treatment, storage, and/or disposal of dangerous and/or mixed waste. Dangerous waste management units covered by this plan include: less-than-90-day accumulation area(s); pool cellsmore » 1-8 and 12 storage units; and process cells A-G storage units. This training plan describes general requirements, worker categories, and provides course descriptions for operation of the WESF permitted miscellaneous storage units and the Less-than-90-Day Accumulation Areas.« less

Planning of Agro-Tourism Development, Specific Location in Green Open Space Sarbagita Area, Bali Province

NASA Astrophysics Data System (ADS)

Lanya, I.; Subadiyasa, N.; Sardiana, K.; Ratna Adi, G. P.

2018-02-01

Tourism development has a negative impact on agricultural land in Bali, resulted in the transfer of rice field of 800 ha/year. Subak rice field area as a world cultural heritage, requires conservation strategy, increasing economic and environmental value, through integrated agriculture development with tourism. Tourism destination planning in the form of tourist destination (TD) and tourism object (TO) by raising local genius, at specific location, is expected to preserve nature and culture, as well as the economic value of the region. Research Methods: (1) identification of agrarian cultures, (2) field survey, (3) mapping of site specific TD/TO plans, and (4) compile documents of agro-tourism road map based on local genius. Seven subak areas in the green open space area have the potential to develop new TD/TO, namely: (1) Gedon2Subak in Tanah Lot area, is developed for the preservation of agriculture, the implementation of the zoning plan of the sacred, madya and nista areas, (2) the Kerdung and Penatih Subak areas, developed for urban farming in Denpasar City, (3) Cangi south Subak area, built for agro-tourism plasmanutfah banana and Cemagi Let Subak area developed agro-tourism food crops and horticulture, (4) Erjeruk Subak area, developed tourism plasmanutfah coconut.

Changes in contraceptive use following integration of family planning into ART Services in Cross River State, Nigeria.

PubMed

McCarraher, Donna R; Vance, Gwyneth; Gwarzo, Usman; Taylor, Douglas; Chabikuli, Otto Nzapfurundi

2011-12-01

One strategy for meeting the contraceptive needs of HIV-positive women is to integrate family planning into HIV services. In 2008 in Cross River State, Nigeria,family planning was integrated into antiretroviral (ART) services in five local government areas. A basic family planning/HIV integration model was implemented in three of these areas, and an enhanced model in the other two. We conducted baseline interviews in 2008 and follow-up interviews 12-14 months later with 274 female ART clients aged 18-45 in 2009 across the five areas. Unmet need for contraception was high at baseline (28-35 percent). We found that modern contraceptive use rose in the enhanced and basic groups; most of the increase was in consistent condom use. Despite an increase in family planning counseling by ART providers, referrals to family planning services for noncondom methods were low. We conclude by presenting alternative strategies for family planning/HIV integration in settings where large families and low contraceptive use are normative.

Assessing the shelf life of cost-efficient conservation plans for species at risk across gradients of agricultural land use.

PubMed

Robillard, Cassandra M; Kerr, Jeremy T

2017-08-01

High costs of land in agricultural regions warrant spatial prioritization approaches to conservation that explicitly consider land prices to produce protected-area networks that accomplish targets efficiently. However, land-use changes in such regions and delays between plan design and implementation may render optimized plans obsolete before implementation occurs. To measure the shelf life of cost-efficient conservation plans, we simulated a land-acquisition and restoration initiative aimed at conserving species at risk in Canada's farmlands. We accounted for observed changes in land-acquisition costs and in agricultural intensity based on censuses of agriculture taken from 1986 to 2011. For each year of data, we mapped costs and areas of conservation priority designated using Marxan. We compared plans to test for changes through time in the arrangement of high-priority sites and in the total cost of each plan. For acquisition costs, we measured the savings from accounting for prices during site selection. Land-acquisition costs and land-use intensity generally rose over time independent of inflation (24-78%), although rates of change were heterogeneous through space and decreased in some areas. Accounting for spatial variation in land price lowered the cost of conservation plans by 1.73-13.9%, decreased the range of costs by 19-82%, and created unique solutions from which to choose. Despite the rise in plan costs over time, the high conservation priority of particular areas remained consistent. Delaying conservation in these critical areas may compromise what optimized conservation plans can achieve. In the case of Canadian farmland, rapid conservation action is cost-effective, even with moderate levels of uncertainty in how to implement restoration goals. © 2016 Society for Conservation Biology.

The Study of Thermal Comfort in Transforming Residential Area in Bandung using ENVI-met Software. Case Study: Progo Street

NASA Astrophysics Data System (ADS)

Aziz Soelaiman, Tubagus M.; Soedarsono, Woerjantari K.; Donny Koerniawan, M.

2018-05-01

Bandung has a high potential in attracting tourists. This potential impact on building function near tourist attraction that can transform residential uses into commercial uses. Progo Street and its surrounding area used as the case study, which is close to Gedung Sate and Riau Street as tourist destinations in Bandung. Moreover, this transformation is also reinforced by the spatial planning policies in Bandung, known as RTRW and RDTR, said that this area will be fully non-residential area. This condition in some cases could affect thermal comfort. This paper provides the changes of thermal comfort phenomenon that occurs using EnviMet software. The study compares Predicted Mean Voted (PMV) as thermal comfort indicator between existing and Bandung detailed spatial plan (RDTR) condition. The result shows that the PMV value of current condition is higher than future planning, nonetheless the planned area will be changed into higher non-residential buildings and less greeneries. Some environmental factors that are used to calculate PMV such as air temperature, mean radiant temperature, humidity, and wind speed are also examined to find out what makes the plan more comfortable than the existing. Simulations using ENVI-met software could be considered in making more objective planning policy in the future.

Underground Test Area Activity Communication/Interface Plan, Nevada National Security Site, Nevada, Revision 0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Farnham, Irene; Rehfeldt, Kenneth

The purpose of this plan is to provide guidelines for effective communication and interfacing between Underground Test Area (UGTA) Activity participants, including the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Field Office (NNSA/NFO) and its contractors. This plan specifically establishes the following: • UGTA mission, vision, and core values • Roles and responsibilities for key personnel • Communication with stakeholders • Guidance in key interface areas • Communication matrix

Structural dynamics division research and technology accomplishments for F.Y. 1991 and plans for F.Y. 1992

NASA Technical Reports Server (NTRS)

Wynne, Eleanor C.

1992-01-01

The work under each technical area is described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to 5 year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest. The structural dynamics division consist of the following branches: configuration aeroelasticity; unsteady aerodynamics; aeroservoelasticity; landing and impact dynamics; and spacecraft dynamics.

Effects of Hurricane Surge Barrier on Hydraulic Environment, Jamaica Bay, New York; Hydraulic Model Investigation

DTIC Science & Technology

1976-09-01

the New York Harbor area and especially the Jamaica Bay complex was used to determine the effects of 13 different hurricane surge barrier plans on...vary directly with the total cross-sectional area of the naviga- tion opening and tidal openings. d. barrier plans B, C-l, C-2, and C-3 would have... plan C-1 with a conservative dye source seaward of the barrier indicated that average dye concentrations will be increased slightly in most areas in

Economic Planning for Multicounty Rural Areas: Application of a Linear Programming Model in Northwest Arkansas. Technical Bulletin No. 1653.

ERIC Educational Resources Information Center

Williams, Daniel G.

Planners in multicounty rural areas can use the Rural Development, Activity Analysis Planning (RDAAP) model to try to influence the optimal growth of their areas among different general economic goals. The model implies that best industries for rural areas have: high proportion of imported inputs; low transportation costs; high value added/output…

IET area plot and utilities plan. Includes drainage. Ralph M. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

IET area plot and utilities plan. Includes drainage. Ralph M. Parsons 902-4-ANP-U-310. Date: February 1954. Approved by INEEL Classification Office for public release. INEEL code no. 035-0100-00-693-106898 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

144. ARAIII Control building (ARA607) Foundation plan. Aerojetgeneral 880area/GCRE607S1. Date: ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

144. ARA-III Control building (ARA-607) Foundation plan. Aerojet-general 880-area/GCRE-607-S-1. Date: February 1958. Ineel index code no. 063-0607-60-013-102568. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

153. ARAIII Reactor building (ARA608) Foundation plan. Aerojetgeneral 880area/GCRE608S1. Date: ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

153. ARA-III Reactor building (ARA-608) Foundation plan. Aerojet-general 880-area/GCRE-608-S-1. Date: February 1958. Ineel index code no. 063-0608-60-013-102653. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

76 FR 20853 - Approval and Promulgation of Air Quality Implementation Plans; Kentucky; Approval of Section 110...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-14

... NAAQS through the year 2020 for the Four Kentucky Areas. These maintenance plans meet applicable... period of 10 years after redesignation, consistent with the CAA section 175A(a). EPA approved Kentucky's... attainment areas) were required to submit 10-year maintenance plans pursuant to section 110(a)(1) of the CAA...

75 FR 64675 - Approval and Promulgation of Implementation Plans and Designation of Areas for Air Quality...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-20

... approve a request from the State of Texas to redesignate the Beaumont/Port Arthur (BPA) Texas ozone... making a final determination that the BPA nonattainment area has attained the 1997 8- hour ozone NAAQS... BPA State Implementation Plan (SIP), a 1997 8-hour ozone maintenance plan that includes a 2021 Motor...

Recent Experience with Urban School Choice Plans. ERIC/CUE Digest Number 127.

ERIC Educational Resources Information Center

Cookson, Peter W., Jr.; Shroff, Sonali M.

School choice plans have been widely adopted, and most urban areas have a limited choice plan of some sort. This digest presents an overview of different choice strategies by reviewing the experiences of several urban areas. Minnesota has statewide open enrollment for all students, making all public schools throughout the state open to all…

77 FR 75386 - Approval and Promulgation of Air Quality Implementation Plans; Virginia; Fredericksburg 8-Hour...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-20

... 52.2424(c) for the Fredericksburg Area. This action corrects these oversights. Section 553 of the... Plan for the Fredericksburg Area to read as follows: Sec. 52.2420 Identification of plan. * * * * * (e... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R03-OAR-2012-0444; FRL-9760-9] Approval and...

Education and Employment Issues. Issue Area Plan for Fiscal Year 1997-99.

ERIC Educational Resources Information Center

General Accounting Office, Washington, DC. Health, Education, and Human Services Div.

This publication outlines the issues in the areas of education and employment that the General Accounting Office plans to investigate and the focus of the planned work for Fiscal Years 1997-99. The principal issues to be investigated are the following: (1) using federal resources to support and encourage state and local efforts to provide…

75 FR 29671 - Approval and Promulgation of Air Quality Implementation Plans: Florida; Approval of Section 110(a...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-27

... how each area will continue attainment of the 1997 8-hour ozone NAAQS, and provide contingency... one of these areas is found to violate the 1997 ozone standards, the contingency plan section of each... returns to maintenance of the 1997 ozone standards. Please see section (d) Contingency Plan, below, for...

Federal employees health program experiences lack of competition in some areas, raising cost concerns for exchange plans.

PubMed

McBride, Timothy D; Barker, Abigail R; Pollack, Lisa M; Kemper, Leah M; Mueller, Keith J

2012-06-01

The Affordable Care Act calls for creation of health insurance exchanges designed to provide private health insurance plan choices. The Federal Employees Health Benefits Program is a national model that to some extent resembles the planned exchanges. Both offer plans at the state level but are also overseen by the federal government. We examined the availability of plans and enrollment levels in the Federal Employees Health Benefits Program throughout the United States in 2010. We found that although plans were widely available, enrollment was concentrated in plans owned by just a few organizations, typically Blue Cross/Blue Shield plans. Enrollment was more concentrated in rural areas, which may reflect historical patterns of enrollment or lack of provider networks. Average biweekly premiums for an individual were lowest ($58.48) in counties where competition was extremely high, rising to $65.13 where competition was extremely low. To make certain that coverage sold through exchanges is affordable, policy makers may need to pay attention to areas where there is little plan competition and take steps through risk-adjustment policies or other measures to narrow differences in premiums and out-of-pocket expenses for consumers.

Oil, biological communities and contingency planning

USGS Publications Warehouse

Albers, P.H.; Frink, Lynne; Ball-Weir, Katherine; Smith, Charlotte

1995-01-01

The Oil Pollution Act of 1990 mandates the inclusion of a fish and wildlife response plan in the National Contingency Plan (NCP) and the creation of Area Committees that must develop an Area Contingency Plan (ACP). Area Contingency Plans must include a detailed annex containing a Fish and Wildlife and Sensitive Environments Plan. Tank vessels, offshore facilities, and certain onshore facilities must have response plans consistent with the requirements of the NCP and the ACP. New regulations to supersede the Type A and B procedures of the Natural Resources Damage Assessment Regulations are being developed for oil spills. Currently, four assessment methods have been proposed: (1) Type A, (2) comprehensive (Type B), (3) intermediate (between types A and B), and (4) compensation tables. The Oil Spill Liability Trust Fund is approaching its ceiling of $1 billion, but only $50 million has been appropriated. Effective biological contingency planning requires extensive knowledge of (1) the environmental fate of petroleum, (2) the effects of petroleum on organisms, (3) the existing biological resources, and (4) the establishment of a system of biological priorities. The characteristics and fate of petroleum and the biological effects of petroleum are reviewed. Assessment of biological resources includes plant and animal distributions, important habitat, endangered or threatened species, and economic considerations. The establishment by Area Committees of priorities for environmental protection, injury assessment, and restoration will promote efficient spill response. Three special issues are discussed: (1) improving our ability to restore natural resources, (2) the potential role of biological diversity in spill response planning, and (3) planning for animal rehabilitation.

Resource management and operations in central North Dakota: Climate change scenario planning workshop summary November 12-13, 2015, Bismarck, ND

USGS Publications Warehouse

Fisichelli, Nicholas A.; Schuurman, Gregor; Symstad, Amy J.; Ray, Andrea; Friedman, Jonathan M.; Miller, Brian; Rowland, Erika

2016-01-01

The Scaling Climate Change Adaptation in the Northern Great Plains through Regional Climate Summaries and Local Qualitative-Quantitative Scenario Planning Workshops project synthesizes climate data into 3-5 distinct but plausible climate summaries for the northern Great Plains region; crafts quantitative summaries of these climate futures for two focal areas; and applies these local summaries by developing climate-resource-management scenarios through participatory workshops and, where possible, simulation models. The two focal areas are central North Dakota and southwest South Dakota (Figure 1). The primary objective of this project is to help resource managers and scientists in a focal area use scenario planning to make management and planning decisions based on assessments of critical future uncertainties.This report summarizes project work for public and tribal lands in the central North Dakota focal area, with an emphasis on Knife River Indian Villages National Historic Site. The report explainsscenario planning as an adaptation tool in general, then describes how it was applied to the central North Dakota focal area in three phases. Priority resource management and climate uncertainties were identified in the orientation phase. Local climate summaries for relevant, divergent, and challenging climate scenarios were developed in the second phase. In the final phase, a two-day scenario planning workshop held November 12-13, 2015 in Bismarck, ND, featured scenario development and implications, testing management decisions, and methods for operationalizing scenario planning outcomes.

Resource management and operations in southwest South Dakota: Climate change scenario planning workshop summary January 20-21, 2016, Rapid City, SD

USGS Publications Warehouse

Fisichelli, Nicholas A.; Schuurman, Gregor W.; Symstad, Amy J.; Ray, Andrea; Miller, Brian; Cross, Molly; Rowland, Erika

2016-01-01

The Scaling Climate Change Adaptation in the Northern Great Plains through Regional Climate Summaries and Local Qualitative-Quantitative Scenario Planning Workshops project synthesizes climate data into 3-5 distinct but plausible climate summaries for the northern Great Plains region; crafts quantitative summaries of these climate futures for two focal areas; and applies these local summaries by developing climate-resource-management scenarios through participatory workshops and, where possible, simulation models. The two focal areas are central North Dakota and southwest South Dakota (Figure 1). The primary objective of this project is to help resource managers and scientists in a focal area use scenario planning to make management and planning decisions based on assessments of critical future uncertainties.This report summarizes project work for public and tribal lands in the southwest South Dakota grasslands focal area, with an emphasis on Badlands National Park and Buffalo Gap National Grassland. The report explains scenario planning as an adaptation tool in general, then describes how it was applied to the focal area in three phases. Priority resource management and climate uncertainties were identified in the orientation phase. Local climate summaries for relevant, divergent, and challenging climate scenarios were developed in the second phase. In the final phase, a two-day scenario planning workshop held January 20-21, 2016 in Rapid City, South Dakota, featured scenario development and implications, testing management decisions, and methods for operationalizing scenario planning outcomes.

Assessment of water resources and the potential effects from oil and gas development in the Bureau of Land Management Tri-County planning area, Sierra, Doña Ana, and Otero Counties, New Mexico

USGS Publications Warehouse

Blake, Johanna M.; Miltenberger, Keely; Stewart, Anne M.; Ritchie, Andre; Montoya, Jennifer; Durr, Corey; McHugh, Amy; Charles, Emmanuel

2018-02-07

The U.S. Geological Survey (USGS), in cooperation with the Bureau of Land Management, conducted a study to assess the water resources and potential effects on the water resources from oil and gas development in the Tri-County planning area, Sierra, Doña Ana, and Otero Counties, New Mexico. Publicly available data were used to assess these resources and effects and to identify data gaps in the Tri-County planning area.The Tri-County planning area includes approximately 9.3 million acres and is within the eastern extent of the Basin and Range Province, which consists of mountain ranges and low elevation basins. Three specific areas of interest within the Tri-County planning area are the Jornada del Muerto, Tularosa Basin, and Otero Mesa, which is adjacent to the Salt Basin. Surface-water resources are limited in the Tri-County planning area, with the Rio Grande as the main perennial river flowing from north to south through Sierra and Doña Ana Counties. The Tularosa Creek is an important surface-water resource in the Tularosa Basin. The Sacramento River, which flows southeast out of the Sacramento Mountains, is an important source of recharge to aquifers in the Salt Basin. Groundwater resources vary in aquifer type, depth to water, and water quality. For example, the Jornada del Muerto, Tularosa Basin, and Salt Basin each have shallow and deep aquifer systems, and water can range from freshwater, with less than 1,000 milligrams per liter (mg/L) of total dissolved solids, to brine, with greater than 35,000 mg/L of total dissolved solids. Water quality in the Tri-County planning area is affected by the dissolution of salt deposits and evaporation which are common in arid regions such as southern New Mexico. The potential for oil and gas development exists in several areas within the Tri-County area. As many as 81 new conventional wells and 25 coalbed natural gas wells could be developed by 2035. Conventional oil and gas well construction in the Tri-County planning area is expected to require 1.53 acre-feet (acre-ft) (500,000 gallons) of water per well, similar to requirements in the nearby Permian Basin of New Mexico, while construction of unconventional wells is expected to require 7.3 acre-ft of water per well. Produced waters in the Permian Basin have high total dissolved solids, in the brackish to brine range.Data gaps identified in this study include the limited detailed data on surface-water resources, the lack of groundwater data in areas of interest, and the lack of water chemistry data related to oil and gas development issues. Surface waters in the Tri-County planning area are sparse; some streams are perennial, and most are ephemeral. A more detailed study of the ephemeral channels and their interaction with groundwater could provide a better understanding of the importance of these surface-water resources. Groundwater data used in this study are from the USGS National Water Information System, which does not have continuous water-level depth data at many of the sites in the Tri-County planning area. On Otero Mesa, no recurrent groundwater-level data are available at any one site. The water-quality data compiled in this study provide a good overview of the general chemistry of groundwater in the Tri-County planning area. To fully understand the groundwater resources, it would be helpful to have more wells in specific areas of interest for groundwater-level and water-quality measurements.

15 CFR 923.25 - Shoreline erosion/mitigation planning.

Code of Federal Regulations, 2010 CFR

2010-01-01

... purpose in developing this planning process is to give special attention to erosion issues. This special management attention may be achieved by designating erosion areas as areas of particular concern pursuant to...

Planning a tourism landscape in geosite area: Sipiso-piso waterfall

NASA Astrophysics Data System (ADS)

Vinky Rahman, N.; Ginting, Nurlisa; Subhilhar; Narisa, Nindya

2018-03-01

Landscape is one of the valuable assets in tourism, especially in rural tourism. Good landscape planning can be increasing the tourism in one place. In Geopark area, landscape planning is also necessary, and it is because geopark area is also a landscape. This paper aims to create a landscape planning concept in Sipiso-Piso Waterfall that can be used to improve the tourism in Sipiso-piso Waterfall. The method that used in this paper is a qualitative method that is used interviews with related stakeholders like, local figure, government, and academic, and field observation in the study area. The data obtained would be analyzed with four elements of landscape namely, open space, pedestrian path, street circulation, and street furniture. The result shows that the four elements of landscape in Sipiso-Piso Waterfall is still not proper and needs improvement.

Space human factors discipline science plan

NASA Technical Reports Server (NTRS)

1991-01-01

The purpose of this Discipline Science Plan is to provide a conceptual strategy for NASA's Life Sciences Division research and development activities in the comprehensive areas of behavior, performance, and human factors. This document summarizes the current status of the program, outlines available knowledge, establishes goals and objectives, defines critical questions in the subdiscipline areas, and identifies technological priorities. It covers the significant research areas critical to NASA's programmatic requirements for the Extended Duration Orbiter, Space Station Freedom, and Exploration mission science activities. These science activities include ground-based and flight; basic, applied and operational; and animal and human research and development. This document contains a general plan that will be used by both NASA Headquarters program offices and the field centers to review and plan basic, applied, and operational research and development activities, both intramural and extramural, in this area.

Regulation of hepatic bile acid transporters Ntcp and Bsep expression.

PubMed

Cheng, Xingguo; Buckley, David; Klaassen, Curtis D

2007-12-03

Sodium-taurocholate cotransporting polypeptide (Ntcp) and bile salt export pump (Bsep) are two key transporters for hepatic bile acid uptake and excretion. Alterations in Ntcp and Bsep expression have been reported in pathophysiological conditions. In the present study, the effects of age, gender, and various chemicals on the regulation of these two transporters were characterized in mice. Ntcp and Bsep mRNA levels in mouse liver were low in the fetus, but increased to its highest expression at parturition. After birth, mouse Ntcp and Bsep mRNA decreased by more than 50%, and then gradually increased to adult levels by day 30. Expression of mouse Ntcp mRNA and protein exhibit higher levels in female than male livers. No gender difference exists in BSEP/Bsep expression in human and mouse livers. Hormone replacements conducted in gonadectomized, hypophysectomized, and lit/lit mice indicate that female-predominant Ntcp expression in mouse liver is due to the inhibitory effect of male-pattern GH secretion, but not sex hormones. Ntcp and Bsep expression are in general resistant to induction by a large battery of microsomal enzyme inducers. Administration of cholestyramine increased Ntcp, whereas chenodeoxycholic acid (CDCA) increased Bsep mRNA expression. In conclusion, mouse Ntcp and Bsep are regulated by age, gender, cholestyramine, and bile acid, but resistant to induction by most microsomal enzyme inducers.

Identification of the Key Genes and Pathways in Esophageal Carcinoma.

PubMed

Su, Peng; Wen, Shiwang; Zhang, Yuefeng; Li, Yong; Xu, Yanzhao; Zhu, Yonggang; Lv, Huilai; Zhang, Fan; Wang, Mingbo; Tian, Ziqiang

2016-01-01

Objective . Esophageal carcinoma (EC) is a frequently common malignancy of gastrointestinal cancer in the world. This study aims to screen key genes and pathways in EC and elucidate the mechanism of it. Methods . 5 microarray datasets of EC were downloaded from Gene Expression Omnibus. Differentially expressed genes (DEGs) were screened by bioinformatics analysis. Gene Ontology (GO) enrichment, Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment, and protein-protein interaction (PPI) network construction were performed to obtain the biological roles of DEGs in EC. Quantitative real-time polymerase chain reaction (qRT-PCR) was used to verify the expression level of DEGs in EC. Results . A total of 1955 genes were filtered as DEGs in EC. The upregulated genes were significantly enriched in cell cycle and the downregulated genes significantly enriched in Endocytosis. PPI network displayed CDK4 and CCT3 were hub proteins in the network. The expression level of 8 dysregulated DEGs including CDK4, CCT3, THSD4, SIM2, MYBL2, CENPF, CDCA3, and CDKN3 was validated in EC compared to adjacent nontumor tissues and the results were matched with the microarray analysis. Conclusion . The significantly DEGs including CDK4, CCT3, THSD4, and SIM2 may play key roles in tumorigenesis and development of EC involved in cell cycle and Endocytosis.

Swertianlarin, an Herbal Agent Derived from Swertia mussotii Franch, Attenuates Liver Injury, Inflammation, and Cholestasis in Common Bile Duct-Ligated Rats

PubMed Central

Zhang, Liangjun; Cheng, Ying; Du, Xiaohuang; Chen, Sheng; Feng, Xinchan; Gao, Yu; Li, Shaoxue; Liu, Li; Yang, Mei; Chen, Lei; Peng, Zhihong; Yang, Yong; Luo, Weizao; Wang, Rongquan; Chen, Wensheng

2015-01-01

Swertianlarin is an herbal agent abundantly distributed in Swertia mussotii Franch, a Chinese traditional herb used for treatment of jaundice. To study the therapeutic effect of swertianlarin on cholestasis, liver injury, serum proinflammatory cytokines, and bile salt concentrations were measured by comparing rats treated with swertianlarin 100 mg/kg/d or saline for 3, 7, or 14 days after bile duct ligation (BDL). Serum alanine aminotransferase (ATL) and aspartate aminotransferase (AST) levels were significantly decreased in BDL rats treated with swertianlarin for 14 days (P < 0.05). The reduced liver injury in BDL rats by swertianlarin treatment for 14 days was further confirmed by liver histopathology. Levels of serum tumor necrosis factor alpha (TNFα) were decreased by swertianlarin in BDL rats for 3 and 7 days (P < 0.05). Moreover, reductions in serum interleukins IL-1β and IL-6 levels were also observed in BDL rats treated with swertianlarin (P < 0.05). In addition, most of serum toxic bile salt concentrations (e.g., chenodeoxycholic acid (CDCA) and deoxycholic acid (DCA)) in cholestatic rats were decreased by swertianlarin (P < 0.05). In conclusion, the data suggest that swertianlarin derived from Swertia mussotii Franch attenuates liver injury, inflammation, and cholestasis in bile duct-ligated rats. PMID:26273316

Supermarket access, transport mode and BMI: the potential for urban design and planning policy across socio-economic areas.

PubMed

Murphy, Maureen; Koohsari, Mohammad Javad; Badland, Hannah; Giles-Corti, Billie

2017-12-01

To investigate dietary intake, BMI and supermarket access at varying geographic scales and transport modes across areas of socio-economic disadvantage, and to evaluate the implementation of an urban planning policy that provides guidance on spatial access to supermarkets. Cross-sectional study used generalised estimating equations to investigate associations between supermarket density and proximity, vegetable and fruit intake and BMI at five geographic scales representing distances people travel to purchase food by varying transport modes. A stratified analysis by area-level disadvantage was conducted to detect optimal distances to supermarkets across socio-economic areas. Spatial distribution of supermarket and transport access was analysed using a geographic information system. Melbourne, Australia. Adults (n 3128) from twelve local government areas (LGA) across Melbourne. Supermarket access was protective of BMI for participants in high disadvantaged areas within 800 m (P=0·040) and 1000 m (P=0·032) road network buffers around the household but not for participants in less disadvantaged areas. In urban growth area LGA, only 26 % of dwellings were within 1 km of a supermarket, far less than 80-90 % of dwellings suggested in the local urban planning policy. Low public transport access compounded disadvantage. Rapid urbanisation is a global health challenge linked to increases in dietary risk factors and BMI. Our findings highlight the importance of identifying the most appropriate geographic scale to inform urban planning policy for optimal health outcomes across socio-economic strata. Urban planning policy implementation in disadvantaged areas within cities has potential for reducing health inequities.

76 FR 14805 - Approval and Promulgation of Air Quality Implementation Plans; New Hampshire; Determination of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-18

... Implementation Plans (SIPs) related to attainment of the 1997 8-hour ozone NAAQS for so long as the area... related to attainment of the 1997 8-hour ozone NAAQS for this area, for so long as the area continues to... moderate 1997 8-hour ozone nonattainment area has attained the 1997 8-hour National Ambient Air Quality...

78 FR 16827 - Designation of Areas for Air Quality Planning Purposes; State of California; Imperial Valley...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-19

...EPA is proposing to clarify the description of the Imperial Valley planning area, an area designated as nonattainment for the national ambient air quality standard for particulate matter with an aerodynamic diameter of a nominal 10 microns or less (PM10). EPA is not proposing to change the boundaries of the PM10 area or the status of the area as a ``serious'' PM10 nonattainment area but is proposing to clarify the description of this partial county area in the Code of Federal Regulations.

Wanaket Wildlife Area Management Plan : Five-Year Plan for Protecting, Enhancing, and Mitigating Wildlife Habitat Losses for the McNary Hydroelectric Facility.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Confederated Tribes of the Umatilla Indian Reservation Wildlife Program

The Confederated Tribes of the Umatilla Indian Reservation (CTUIR) propose to continue to protect, enhance, and mitigate wildlife and wildlife habitat at the Wanaket Wildlife Area. The Wanaket Wildlife Area was approved as a Columbia River Basin Wildlife Mitigation Project by the Bonneville Power Administration (BPA) and Northwest Power Planning Council (NWPPC) in 1993. This management plan will provide an update of the original management plan approved by BPA in 1995. Wanaket will contribute towards meeting BPA's obligation to compensate for wildlife habitat losses resulting from the construction of the McNary Hydroelectric facility on the Columbia River. By funding themore » enhancement and operation and maintenance of the Wanaket Wildlife Area, BPA will receive credit towards their mitigation debt. The purpose of the Wanaket Wildlife Area management plan update is to provide programmatic and site-specific standards and guidelines on how the Wanaket Wildlife Area will be managed over the next five years. This plan provides overall guidance on both short and long term activities that will move the area towards the goals, objectives, and desired future conditions for the planning area. The plan will incorporate managed and protected wildlife and wildlife habitat, including operations and maintenance, enhancements, and access and travel management. Specific project objectives are related to protection and enhancement of wildlife habitats and are expressed in terms of habitat units (HU's). Habitat units were developed by the US Fish and Wildlife Service's Habitat Evaluation Procedures (HEP), and are designed to track habitat gains and/or losses associated with mitigation and/or development projects. Habitat Units for a given species are a product of habitat quantity (expressed in acres) and habitat quality estimates. Habitat quality estimates are developed using Habitat Suitability Indices (HSI). These indices are based on quantifiable habitat features such as vegetation height, shrub cover, or other parameters, which are known to provide life history requisites for mitigation species. Habitat Suitability Indices range from 0 to 1, with an HSI of 1 providing optimum habitat conditions for the selected species. One acre of optimum habitat provides one Habitat Unit. The objective of continued management of the Wanaket Wildlife Mitigation Area, including protection and enhancement of upland and wetland/wetland associated cover types, is to provide and maintain 2,334 HU's of protection credit and generate 2,495 HU's of enhancement credit by the year 2004.« less

ADM. Service Building (TAN603). Floor plan. Names of functional areas. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

ADM. Service Building (TAN-603). Floor plan. Names of functional areas. Ralph M. Parsons 902-2-ANY-603-A 43. Date: December 1952. Approved by INEEL Classification Office for public release. INEEL index code no. 033-0603-00-693-106718 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

33 CFR 155.1040 - Response plan requirements for unmanned tank barges carrying oil as a primary cargo.

Code of Federal Regulations, 2013 CFR

2013-07-01

... the towing vessel crew and facility or fleeting area personnel, if any, to initiate a response and... functional areas and must further include information for key components within each functional area: (i...) Spill response operations; (vi) Planning; (vii) Logistics support; and (viii) Finance. (5) The...

33 CFR 155.1040 - Response plan requirements for unmanned tank barges carrying oil as a primary cargo.

Code of Federal Regulations, 2011 CFR

2011-07-01

... the towing vessel crew and facility or fleeting area personnel, if any, to initiate a response and... functional areas and must further include information for key components within each functional area: (i...) Spill response operations; (vi) Planning; (vii) Logistics support; and (viii) Finance. (5) The...

33 CFR 155.1040 - Response plan requirements for unmanned tank barges carrying oil as a primary cargo.

Code of Federal Regulations, 2012 CFR

2012-07-01

... the towing vessel crew and facility or fleeting area personnel, if any, to initiate a response and... functional areas and must further include information for key components within each functional area: (i...) Spill response operations; (vi) Planning; (vii) Logistics support; and (viii) Finance. (5) The...

33 CFR 155.1040 - Response plan requirements for unmanned tank barges carrying oil as a primary cargo.

Code of Federal Regulations, 2014 CFR

2014-07-01

... the towing vessel crew and facility or fleeting area personnel, if any, to initiate a response and... functional areas and must further include information for key components within each functional area: (i...) Spill response operations; (vi) Planning; (vii) Logistics support; and (viii) Finance. (5) The...

SPERTI plot plan for control area. Includes Control Building (PER601), ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

SPERT-I plot plan for control area. Includes Control Building (PER-601), Gate House (PER-603), well sand settling tank, substation, and septic system. Date: February 1955. INEEL index no. 760-0101-00-396-109104 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

75 FR 6218 - New Melones Lake Area Resource Management Plan, Tuolumne and Calaveras Counties, CA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-08

... DEPARTMENT OF THE INTERIOR Bureau of Reclamation New Melones Lake Area Resource Management Plan...) has made available for public review a Final RMP/EIS for the New Melones Lake Area. The Final RMP/EIS... Dan Holsapple, Acting New Melones Resource Manager, Bureau of Reclamation, at 209-536- 9094...

78 FR 22501 - Designation of Areas for Air Quality Planning Purposes; State of Nevada; Total Suspended Particulate

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-16

... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 81 [EPA-R09-OAR-2013-0104; FRL-9802-5] Designation of Areas for Air Quality Planning Purposes; State of Nevada; Total Suspended Particulate AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to delete certain area...

Land use-based landscape planning and restoration in mine closure areas.

PubMed

Zhang, Jianjun; Fu, Meichen; Hassani, Ferri P; Zeng, Hui; Geng, Yuhuan; Bai, Zhongke

2011-05-01

Landscape planning and restoration in mine closure areas is not only an inevitable choice to sustain mining areas but also an important path to maximize landscape resources and to improve ecological function in mine closure areas. The analysis of the present mine development shows that many mines are unavoidably facing closures in China. This paper analyzes the periodic impact of mining activities on landscapes and then proposes planning concepts and principles. According to the landscape characteristics in mine closure areas, this paper classifies available landscape resources in mine closure areas into the landscape for restoration, for limited restoration and for protection, and then summarizes directions for their uses. This paper establishes the framework of spatial control planning and design of landscape elements from "macro control, medium allocation and micro optimization" for the purpose of managing and using this kind of special landscape resources. Finally, this paper applies the theories and methods to a case study in Wu'an from two aspects: the construction of a sustainable land-use pattern on a large scale and the optimized allocation of typical mine landscape resources on a small scale.

Financial planning considerations at retirement.

PubMed

Cole, R J

1998-03-01

The process of retirement planning is a difficult one for a physician. The Planning process should address the areas of Investment Planning, Estate Planning, and Risk Management. This article examines each of these dimensions with special emphasis on Modern Portfolio Theory as the basis for investment planning.

75 FR 33562 - Approval and Promulgation of Implementation Plans and Designations of Areas for Air Quality...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-14

...EPA is proposing to determine that the Birmingham, Alabama, nonattainment area for the 2006 24-hour fine particulate matter (PM2.5) National Ambient Air Quality Standard (NAAQS) has attained the 2006 24-hour PM2.5 NAAQS. This proposed determination is based upon complete, quality assured, quality controlled, and certified ambient air monitoring data for the years 2007-2009 showing that this area has monitored attainment of the 2006 24-hour PM2.5 NAAQS. If this proposed determination is made final, the requirement for the State of Alabama to submit an attainment demonstration and associated reasonably available control measures (RACM), reasonable further progress (RFP) plan, contingency measures, and other planning State Implementation Plans (SIPs) related to attainment of the 2006 24-hour PM2.5 standard for the Birmingham, Alabama, PM2.5 nonattainment area, shall be suspended for as long as this area continues to meet the 2006 24-hour PM2.5 NAAQS.

300 Area waste acid treatment system closure plan. Revision 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-03-01

This section provides a description of the Hanford Site, identifies the proposed method of 300 Area Waste Acid Treatment System (WATS) closure, and briefly summarizes the contents of each chapter of this plan.

IVHS Denver Metro Area, Strategic Plan

DOT National Transportation Integrated Search

1992-10-01

THE IVHS STRATEGIC PLAN WHICH FOLLOWS DEFINES THE CURRENT SITUATION AND EXISTING CONDITIONS IN THE DENVER AREA; PROVIDES BACKGROUND INFORMATION DESCRIBING IVHS SYSTEMS; DETAILS REGIONAL GOALS AND OBJECTIVES; LISTS AND DESCRIBES THE MENU OF 44 POTENTI...

Site Plan: Real Estate, Custer Reserve Forces Training Area, Military ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Site Plan: Real Estate, Custer Reserve Forces Training Area, Military Reservation, USACOE, 20 July 1948 - Fort Custer Military Reservation, Bounded by Territorial, Dickman, & Longman Roads & Route 94 Business, Battle Creek, Calhoun County, MI

Planning for transportation in rural areas

DOT National Transportation Integrated Search

2001-07-01

The purpose of this document, Planning for Transportation in Rural Areas, is to provide a resource to rural planners, city and county engineers, stakeholders, local officials, and other decision-makers involved with developing rural transportation pl...

78 FR 36568 - Notice of Availability of the Record of Decision for the Approved Imperial Sand Dunes Recreation...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-18

... for the deaf (TDD) may call the Federal Information Relay Service (FIRS) at 1-800-877-8339 to contact... lands included in the planning area encompass about 215,000 acres, of which approximately 12,000 acres are non- Federal lands for which these planning decisions do not apply. The planning area is located...

126. ARAII Plot plan showing location of SL1 power plant ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

126. ARA-II Plot plan showing location of SL-1 power plant (reactor) building, and planned location of administrative and technical support building. C.A. Sundberg and Associates 866-area/ALPR-606-U-1. Date: May 1958. Ineel index code no. 070-0100-00-822-102834. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

78 FR 59261 - Approval and Promulgation of Implementation Plans; Designation of Areas for Air Quality Planning...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-26

... continue to attain the 24-hour PM 10 NAAQS for at least 10 years beyond redesignation (i.e., through 2023... maintenance demonstration showing how the area will continue to attain the 24-hour PM 10 NAAQS for 10 years... serves as the Sacramento PM 10 Maintenance Plan's attainment year emissions inventory, as satisfying the...

78 FR 38223 - Approval and Promulgation of Implementation Plans; Designation of Areas for Air Quality Planning...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-26

... demonstration showing how the area will continue to attain the 24-hour PM 10 NAAQS for at least 10 years beyond...; California; South Coast Air Basin; Approval of PM 10 Maintenance Plan and Redesignation to Attainment for the PM 10 Standard AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY: EPA is...

[Final Resolutions Adopted by the Conference on Planning of Rural Areas in Europe, 7 October 1978].

ERIC Educational Resources Information Center

Council of Europe, Strasbourg (France).

Two final resolutions were adopted by the Council of Europe at the October 1978 European Conference of Ministers Responsible for Regional Planning. Resolution 1 focused on guidelines for the planning of rural areas in Europe. Strategies and policies called for: a more balanced development which makes the living conditions of different regions as…

The development of the 1999 management plan for the Tasmanian Wilderness World Heritage Area (Australia)

Treesearch

Nicholas Sawyer

2000-01-01

This paper describes the multi-stage public consultation process and other aspects of the development by the Tasmanian Parks and Wildlife Service of the second (1999) management plan for the Tasmanian Wilderness World Heritage Area (Australia). It describes the background to, and rationale for, the process used in developing the plan; it details the consultation...

77 FR 33232 - Notice of Intent To Prepare Environmental Documents and Proposed Plan Amendments for Off-Highway...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-05

... for decisions at the land use planning level in accordance with policies in the BLM Land Use Planning..., soils, sociology, and economics. The Big Willow Route Designation and the Blacks Creek Reservoir Area... Willow area. The CRMP provides for OHV uses on public land by designating use levels (i.e., open; limited...

Minnesota Area Vocational-Technical Institutes. A Plan to Address Declining Enrollments and Resources. Submitted to the Minnesota State Legislature

ERIC Educational Resources Information Center

Minnesota State Board for Vocational Education, St. Paul.

In March 1982, the Minnesota Division of Vocational-Technical Education received requests from State legislators to develop an action plan to address the problems of declining enrollments and resources. In response to this request, a plan was developed whereby area vocational-technical institutes (AVTIs) in the State would (1) promote a process…

Montana geothermal commercialization planning. Semi-annual progress report, January 1, 1979-June 30, 1979

DOE Office of Scientific and Technical Information (OSTI.GOV)

Birkby, J.; Brown, K.; Chapman, M.

1979-06-01

Area development plans were prepared which describe geothermal resources and their potential use on a county or multicounty basis. Development plans for two areas are presented. Cost analyses show that the proximity of the geothermal resource to the end user is the most important criterion in geothermal energy development. Thirteen tentative site-specific plans are being revised. The analysis of institutional factors affecting geothermal development, the outreach, and the state geothermal are discussed briefly. (MHR)

Dallas Freeway/HOV system planning study: Year 2015. A summary of recommended hov improvements. Interim research report, September 1992-August 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walters, C.H.; Lomax, T.J.; Poe, C.M.

1995-07-01

The Dallas Freeway/High-Occupany Vehicle Lane System Planning Study is a joint project in cooperation with the Texas Department of Transportation (TxDOT), Dallas Area Rapid Transit (DART), the North Central Texas Council of Governments (NCTCOG), and the Texas Transportation Institute (TTI). The intent of this effort is to assist in the development of an area-wide freeway/HOV system that recognizes implementation constraints (right-of-way and construction costs) and provides reasonable peak-hour operating conditions on all freeway facilities, while incorporating the long-range plans developed by TxDOT, DART, and NCTCOG. The proposed system is a set of recommendations to be considered and evaluated as partmore » of the development of the NCTCOG Mobility 2010 Plan Update, the long-range transportation plan for the Dallas area. HOV facilities are a significant part of the recommended system in the Dallas System Planning Study, and their implementation is important to the successful operation of the Dallas area transportation system in the future. The report, therefore, focuses on the recommended HOV improvements from the methodology.« less

A framework for planning of sustainable water and sanitation systems in peri-urban areas.

PubMed

Törnqvist, R; Norström, A; Kärrman, E; Malmqvist, P-A

2008-01-01

There are billions of people around the world that lack access to safe water supply and basic sanitation, a situation which puts the affected in severe health conditions as well as economical and social despair. Many of those lacking adequate water supply and sanitation systems can be found at the fringe of the cities in so called peri-urban areas, especially in the developing world. Planning in these areas is highly complex due to challenging environmental and physical conditions, high population density and unclear institutional boundaries. This article presents a framework aiming to support the planning process for sustainable water and sanitation systems in peri-urban areas. The suggested framework is based on different available planning approaches from a review of literature and websites of organisations and companies. It consists of a recommendation of important steps in the planning process as well as supporting tools. Further, it incorporates a set of sustainability criteria important for the peri-urban context and allows for the development of site specific systems. The framework has the aim to be flexible for different planning situations, and for suiting planners with different perspectives and amount of resources. (c) IWA Publishing 2008.

Computer integrated manufacturing/processing in the HPI. [Hydrocarbon Processing Industry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yoshimura, J.S.

1993-05-01

Hydrocarbon Processing and Systemhouse Inc., developed a comprehensive survey on the status of computer integrated manufacturing/processing (CIM/CIP) targeted specifically to the unique requirements of the hydrocarbon processing industry. These types of surveys and other benchmarking techniques can be invaluable in assisting companies to maximize business benefits from technology investments. The survey was organized into 5 major areas: CIM/CIP planning, management perspective, functional applications, integration and technology infrastructure and trends. The CIM/CIP planning area dealt with the use and type of planning methods to plan, justify implement information technology projects. The management perspective section addressed management priorities, expenditure levels and implementationmore » barriers. The functional application area covered virtually all functional areas of organization and focused on the specific solutions and benefits in each of the functional areas. The integration section addressed the needs and integration status of the organization's functional areas. Finally, the technology infrastructure and trends section dealt with specific technologies in use as well as trends over the next three years. In February 1993, summary areas from preliminary results were presented at the 2nd International Conference on Productivity and Quality in the Hydrocarbon Processing Industry.« less

Setting Priorities for Regional Conservation Planning in the Mediterranean Sea

PubMed Central

Micheli, Fiorenza; Levin, Noam; Giakoumi, Sylvaine; Katsanevakis, Stelios; Abdulla, Ameer; Coll, Marta; Fraschetti, Simonetta; Kark, Salit; Koutsoubas, Drosos; Mackelworth, Peter; Maiorano, Luigi; Possingham, Hugh P.

2013-01-01

Spatial prioritization in conservation is required to direct limited resources to where actions are most urgently needed and most likely to produce effective conservation outcomes. In an effort to advance the protection of a highly threatened hotspot of marine biodiversity, the Mediterranean Sea, multiple spatial conservation plans have been developed in recent years. Here, we review and integrate these different plans with the goal of identifying priority conservation areas that represent the current consensus among the different initiatives. A review of six existing and twelve proposed conservation initiatives highlights gaps in conservation and management planning, particularly within the southern and eastern regions of the Mediterranean and for offshore and deep sea habitats. The eighteen initiatives vary substantially in their extent (covering 0.1–58.5% of the Mediterranean Sea) and in the location of additional proposed conservation and management areas. Differences in the criteria, approaches and data used explain such variation. Despite the diversity among proposals, our analyses identified ten areas, encompassing 10% of the Mediterranean Sea, that are consistently identified among the existing proposals, with an additional 10% selected by at least five proposals. These areas represent top priorities for immediate conservation action. Despite the plethora of initiatives, major challenges face Mediterranean biodiversity and conservation. These include the need for spatial prioritization within a comprehensive framework for regional conservation planning, the acquisition of additional information from data-poor areas, species or habitats, and addressing the challenges of establishing transboundary governance and collaboration in socially, culturally and politically complex conditions. Collective prioritised action, not new conservation plans, is needed for the north, western, and high seas of the Mediterranean, while developing initial information-based plans for the south and eastern Mediterranean is an urgent requirement for true regional conservation planning. PMID:23577060

New laws on population urged.

PubMed

1976-12-03

A workshop on ''Population and the Law'' sponsored by the Family Planning Organization of the Philippines and the International Planned Parenthood Federation recommended the following changes in Philippine law to implement family planning: legalization of abortion for women whose life or health are endangered by pregnancy and those who become pregnant despite contraceptives; delaying age of marriage to 18; extension of family planning incentives and maternity leave to women in government service; allow trained nurses and midwives to dispense contractives; legalize sterilization; include sterilization in medicare benefits; specify by law which contraceptive drugs may be dispensed by nonphysicians and nonpharmacists in rural areas; legalize premarital family planning counseling; declare family planning materials tax exempt; encourage reluctant doctors to practice sterilization through professional regulatory agencies; extend industrial family planning services to women living near the plant; launch massive information drives to advise young people of the hazards of premarital sex; strict enforcement of abortion laws in areas where illegal abortion still exists; grant women equal rights in area of consent for sterilization; and eliminate the stigma of illegitimacy for those born out of wedlock.

3. "LAUNCH SILOS; AREA PAVING AND GRADING PLAN." Specifications No. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. "LAUNCH SILOS; AREA PAVING AND GRADING PLAN." Specifications No. ENG-04-353-59-73; Drawing No. 5841C-11; D.O. SERIES AW-1525/17; Stamped: RECORD DRAWING AS CONSTRUCTED. Below stamp: Contract No. 6601, Date 18 Sep 59. - Edwards Air Force Base, Air Force Rocket Propulsion Laboratory, Missile Silo Type, Test Area 1-100, northeast end of Test Area 1-100 Road, Boron, Kern County, CA

42 CFR 422.2266 - Deemed approval.

Code of Federal Regulations, 2012 CFR

2012-10-01

... submitted by an MA organization with respect to an MA plan in an area, CMS is deemed not to have disapproved the distribution in all other areas covered by the MA plan and organization except with regard to any...

36 CFR 219.16 - Relationships with interested individuals and organizations.

Code of Federal Regulations, 2010 CFR

2010-07-01

... information about current and historic public uses within an assessment or plan area, about the location of unique and sensitive resources and values and cultural practices related to issues in the plan area; and...

Transportation Management Area Planning Certification Review Primer: Revised January 18, 2018

DOT National Transportation Integrated Search

2018-01-18

This primer outlines key concepts and expectations of a Transportation Management Area (TMA) Planning Certification Review. Reflecting on the collective experiences of past Certification Reviews, this includes references to relevant laws and regulati...

300 Area waste acid treatment system closure plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

LUKE, S.N.

1999-05-17

The Hanford Facility Dangerous Waste Permit Application is considered to be a single application organized into a General Information Portion (document number DOERL-91-28) and a Unit-Specific Portion. The scope of the Unit-Specific Portion includes closure plan documentation submitted for individual, treatment, storage, and/or disposal units undergoing closure, such as the 300 Area Waste Acid Treatment System. Documentation contained in the General Information Portion is broader in nature and could be used by multiple treatment, storage, and/or disposal units (e.g., the glossary provided in the General Information Portion). Whenever appropriate, 300 Area Waste Acid Treatment System documentation makes cross-reference to themore » General Information Portion, rather than duplicating text. This 300 Area Waste Acid Treatment System Closure Plan (Revision 2) includes a Hanford Facility Dangerous Waste Permit Application, Part A, Form 3. Information provided in this closure plan is current as of April 1999.« less

78 FR 16792 - Designation of Areas for Air Quality Planning Purposes; State of California; Imperial Valley...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-19

... (see, e.g., the PM 10 area designations in 40 CFR 81.305 for Coso Junction planning area, Owens Valley..., this action: Is not ``significant regulatory actions'' subject to review by the Office of Management..., 1999); Is not economically significant regulatory actions based on health or safety risks subject to...

78 FR 13712 - U.S. Nuclear Regulatory Commission Planned Monitoring Activities for F-Area Tank Farm at the...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-28

... Monitoring Activities for F-Area Tank Farm at the Savannah River Site, Revision 0 AGENCY: Nuclear Regulatory... carrying out its responsibilities for monitoring DOE's waste disposal activities at the F-Area Tank Farm at... the availability of ``U.S. Nuclear Regulatory Commission Plan for Monitoring Disposal Actions Taken by...

75 FR 61174 - Warner Valley Comprehensive Site Plan, Final Environmental Impact Statement, Lassen Volcanic...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-04

... Warner Valley fen and wetland areas; (3) Removal or repair of Dream Lake Dam and restoration of... project planning area. This area includes Dream Lake Dam, built in 1932 by Alex Sifford, which impounds an... built the 10 structures which now form the core of Drakesbad Guest Ranch Historic District (both Dream...

47 CFR 52.7 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Administration § 52.7 Definitions. As used in this subpart: (a) Area code or numbering plan area (NPA). The term “area code or numbering plan area” refers to the first three digits (NXX) of a ten-digit telephone... “central office code” refers to the second three digits (NXX) of a ten-digit telephone number in the form...

47 CFR 52.7 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Administration § 52.7 Definitions. As used in this subpart: (a) Area code or numbering plan area (NPA). The term “area code or numbering plan area” refers to the first three digits (NXX) of a ten-digit telephone... “central office code” refers to the second three digits (NXX) of a ten-digit telephone number in the form...

47 CFR 52.7 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Administration § 52.7 Definitions. As used in this subpart: (a) Area code or numbering plan area (NPA). The term “area code or numbering plan area” refers to the first three digits (NXX) of a ten-digit telephone... “central office code” refers to the second three digits (NXX) of a ten-digit telephone number in the form...

47 CFR 52.7 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Administration § 52.7 Definitions. As used in this subpart: (a) Area code or numbering plan area (NPA). The term “area code or numbering plan area” refers to the first three digits (NXX) of a ten-digit telephone... “central office code” refers to the second three digits (NXX) of a ten-digit telephone number in the form...

Planning and Providing End-of-life Care in Rural Areas

ERIC Educational Resources Information Center

Wilson, Donna M.; Justice, Christopher; Sheps, Sam; Thomas, Roger; Reid, Pam; Leibovici, Karen

2006-01-01

Context: Approximately 20% of North Americans and 25% of Europeans reside in rural areas. Planning and providing end-of-life (EOL) care in rural areas presents some unique challenges. Purpose: In order to understand these challenges, and other important issues or circumstances, a literature search was conducted to assess the state of science on…

36 CFR 219.2 - Levels of planning and responsible officials.

Code of Federal Regulations, 2014 CFR

2014-07-01

.... Planning occurs at three levels—national strategic planning, NFS unit planning, and project or activity... measures, and strategies for management of the NFS, as well as the other Forest Service mission areas... System unit planning. (1) NFS unit planning results in the development, amendment, or revision of a land...

36 CFR 219.2 - Levels of planning and responsible officials.

Code of Federal Regulations, 2013 CFR

2013-07-01

.... Planning occurs at three levels—national strategic planning, NFS unit planning, and project or activity... measures, and strategies for management of the NFS, as well as the other Forest Service mission areas... System unit planning. (1) NFS unit planning results in the development, amendment, or revision of a land...

An analysis of land use planning and equity issues surrounding hazardous liquid and natural gas transmission pipelines in North Carolina

NASA Astrophysics Data System (ADS)

Osland, Anna Christine

Hazardous liquid and natural gas transmission pipelines have received limited attention by planning scholars even though local development decisions can have broad consequences if a rupture occurs. In this dissertation, I evaluated the implications of land-use planning for reducing risk to transmission pipeline hazards in North Carolina via three investigations. First, using a survey of planning directors in jurisdictions with transmission pipeline hazards, I investigated the land use planning tools used to mitigate pipeline hazards and the factors associated with tool adoption. Planning scholars have documented the difficulty of inducing planning in hazardous areas, yet there remain gaps in knowledge about the factors associated with tool adoption. Despite the risks associated with pipeline ruptures, I found most localities use few mitigation tools, and the adoption of regulatory and informational tools appear to be influenced by divergent factors. Whereas risk perception, commitment, capacity, and community context were associated with total tool and information tool use, only risk perception and capacity factors were associated with regulatory tool use. Second, using interviews of emergency managers and planning directors, I examined the role of agency collaboration for building mitigation capacity. Scholars have highlighted the potential of technical collaboration, yet less research has investigated how inter-agency collaboration shapes mitigation capacity. I identify three categories of technical collaboration, discuss how collaborative spillovers can occur from one planning area to another, and challenge the notion that all technical collaborations result in equal mitigation outcomes. Third, I evaluated characteristics of the population near pipelines to address equity concerns. Surprisingly, I did not find broad support for differences in exposure of vulnerable populations. Nonetheless, my analyses uncovered statistically significant clusters of vulnerable groups within the hazard area. Interestingly, development closer to pipelines was newer than areas farther away, illustrating the failure of land-use planning to reduce development encroachment. Collectively, these results highlight the potential of land-use planning to keep people and development from encroaching on pipeline hazards. While this study indicates that planners in many areas address pipeline hazards, it also illustrates how changes to local practices can further reduce risks to human health, homeland security, and the environment.

The requirements for implementing Sustainable Development Goals (SDGs) and for planning and implementing Integrated Territorial Investments (ITI) in mining areas

NASA Astrophysics Data System (ADS)

Florkowska, Lucyna; Bryt-Nitarska, Izabela

2018-04-01

The notion of Integrated Territorial Investments (ITI) appears more and more frequently in contemporary regional development strategies. Formulating the main assumptions of ITI is a response to a growing need for a co-ordinated, multi-dimensional regional development suitable for the characteristics of a given area. Activities are mainly aimed at improving people's quality of life with their significant participation. These activities include implementing the Sustainable development Goals (SDGs). Territorial investments include, among others, projects in areas where land and building use is governed not only by general regulations (Spatial Planning and Land Development Act) but also by separate legal acts. This issue also concerns areas with active mines and post-mining areas undergoing revitalization. For the areas specified above land development and in particular making building investments is subject to the requirements set forth in the Geological and Mining Law and in the general regulations. In practice this means that factors connected with the present and future mining impacts must be taken into consideration in planning the investment process. This article discusses the role of proper assessment of local geological conditions as well as the current and future mining situation in the context of proper planning and performance of the Integrated Territorial Investment programme and also in the context of implementing the SDGs. It also describes the technical and legislative factors which need to be taken into consideration in areas where mining is planned or where it took place in the past.

Salmon habitat assessment for conservation planning in the lower White Salmon River, Washington

USGS Publications Warehouse

Hardiman, Jill M.; Allen, M. Brady

2015-01-01

In 2011, Condit Dam was removed from the White Salmon River, Washington. Since dam removal, there has been interest among scientists (State and Federal), Tribes, non-profit organizations, and the general public in assessing Pacific salmon habitat and use in the White Salmon River for conservation planning and potential fishery management actions. The study area extended from the lower 6 miles of the White Salmon River to the confluence with the Columbia River, including the former reservoir area. The Mid-Columbia Fisheries Enhancement Group received a grant to initiate efforts to plan for salmon habitat protection in the lower 6 river miles of the White Salmon River. As part of efforts by the Mid-Columbia Fisheries Enhancement Group to conduct conservation planning, the U.S. Geological Survey (USGS) used current and historical habitat information to assist in the planning process. The USGS compiled existing georeferenced habitat data into a Geographic Information System to identify areas of high quality habitat for salmon, potential areas for restoration/improvement, and areas that could be threatened. The primary sources of georeferenced data for this project include a lidar flight contracted by PacifiCorp, bathymetry from USGS, and fall Chinook salmon redd surveys from the U.S. Fish and Wildlife Service and Washington Department of Fish and Wildlife. Redd observations provided support that the study area is a migratory corridor for salmon and steelhead and that the lowest 2–3 miles had the highest concentration of documented fall Chinook salmon redds. The study area has potential for restoration/conservation areas to improve/conserve salmon habitat.

Management self assessment plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Debban, B.L.

Duke Engineering and Services Hanford Inc., Spent Nuclear Fuel Project is responsible for the operation of fuel storage facilities. The SNF project mission includes the safe removal, processing and transportation of Spent Nuclear Fuel from 100 K Area fuel storage basins to a new Storage facility in the Hanford 200 East Area. Its mission is the modification of the 100 K area fuel storage facilities and the construction of two new facilities: the 100 K Area Cold Vacuum Drying Facility, and the 200 East Area Canister Storage Building. The management self assessment plan described in this document is scheduled tomore » begin in April of 1999 and be complete in May of 1999. The management self assessment plan describes line management preparations for declaring that line management is ready to commence operations.« less

131. ARAII Administration building (ARA613) floor plans for first and ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

131. ARA-II Administration building (ARA-613) floor plans for first and second floors. Includes roof plan. Shows use of rooms as offices, laboratory, conference room. F.C. Torkelson Company 842-area/SL-1-613-A-1. Date: October 1958. Ineel index code no. 070-0613-00-851-150718. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

Loads and aeroelasticity division research and technology accomplishments for FY 1982 and plans for FY 1983

NASA Technical Reports Server (NTRS)

Gardner, J. E.

1983-01-01

Accomplishments of the past year and plans for the coming year are highlighted as they relate to five year plans and the objectives of the following technical areas: aerothermal loads; multidisciplinary analysis and optimization; unsteady aerodynamics; and configuration aeroelasticity. Areas of interest include thermal protection system concepts, active control, nonlinear aeroelastic analysis, aircraft aeroelasticity, and rotorcraft aeroelasticity and vibrations.

Urban Area Recovery Planning with Chemical, Biological, and Radiological Hazards: Lessons Learned from Seattle and Denver

DTIC Science & Technology

2012-11-01

Urban Area Recovery Planning with CBR Hazards: Lessons Learned from Seattle and Denver 16 THE PUGET SOUND CATASTROPHIC DISASTER COORDINATION...PLAN – TRANSPORTATION RECOVERY ANNEX The Puget Sound Transportation Recovery Annex supplements the Puget Sound Regional Catastrophic Coordination... Puget Sound Region after a catastrophic incident. This Annex addresses transportation issues in Island, King, Kitsap, Mason, Pierce, Skagit, Snohomish

Underground Test Area Quality Assurance Project Plan Nevada National Security Site, Nevada, Revision 0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Irene Farnham

This Quality Assurance Project Plan (QAPP) provides the overall quality assurance (QA) program requirements and general quality practices to be applied to the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office (NNSA/NSO) Underground Test Area (UGTA) Sub-Project (hereafter the Sub-Project) activities. The requirements in this QAPP are consistent with DOE Order 414.1C, Quality Assurance (DOE, 2005); U.S. Environmental Protection Agency (EPA) Guidance for Quality Assurance Project Plans for Modeling (EPA, 2002); and EPA Guidance on the Development, Evaluation, and Application of Environmental Models (EPA, 2009). The QAPP Revision 0 supersedes DOE--341, Underground Test Area Quality Assurancemore » Project Plan, Nevada Test Site, Nevada, Revision 4.« less

Alvin expeditionary hotline

NASA Astrophysics Data System (ADS)

This note is call for dive requests, coordinated to the extent practical, from those scientists interested in opportunities for an Alvin/Atlantis II expedition to some remote area. In an effort to facilitate planning for Alvin and to help focus the attention of investigators with diverse scientific interests in remote areas, Feenan Jennings of Texas A & M University, College Station, who chairs the University-National Oceanographic Laboratory System's (UNOLS') Alvin Review Committee (ARC), has announced establishment of an Alvin planning bulletin board on electronic mail. The bulletin board, ALVIN.PLANNING, is to help inform potential users of community interest in conducting Alvin/Atlantis II research projects, especially those involving expeditions to remote areas. ALVIN.PLANNING will be implemented early in 1990. Notice and further details will be broadcast throughout the ocean community.

Remedial Design/Remedial Action Work Plan for Operable Units 6-05 and 10-04, Phase IV

DOE Office of Scientific and Technical Information (OSTI.GOV)

R. P. Wells

2006-11-14

This Phase IV Remedial Design/Remedial Action Work Plan addresses the remediation of areas with the potential for UXO at the Idaho National Laboratory. These areas include portions of the Naval Proving Ground, the Arco High-Altitude Bombing Range, and the Twin Buttes Bombing Range. Five areas within the Naval Proving Ground that are known to contain UXO include the Naval Ordnance Disposal Area, the Mass Detonation Area, the Experimental Field Station, The Rail Car Explosion Area, and the Land Mine Fuze Burn Area. The Phase IV remedial action will be concentrated in these five areas. For other areas, such as themore » Arco High-Altitude Bombing Range and the Twin Buttes Bombing Range, ordnance has largely consisted of sand-filled practice bombs that do not pose an explosion risk. Ordnance encountered in these areas will be addressed under the Phase I Operations and Maintenance Plan that allows for the recovery and disposal of ordnance that poses an imminent risk to human health or the environment.« less

76 FR 27290 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia; Kentucky; Ohio...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-11

...EPA is proposing to make two determinations regarding the tri- state Huntington-Ashland, West Virginia-Kentucky-Ohio fine particulate matter (PM2.5) nonattainment Area (hereafter referred to as ``the Huntington-Ashland Area'' or ``Area''). First, EPA is proposing to determine that the Area has attained the 1997 annual average PM2.5 National Ambient Air Quality Standard (NAAQS). This proposed determination of attainment is based upon complete, quality- assured and certified ambient air monitoring data for the 2007-2009 period showing that the Area has attained the 1997 annual PM2.5 NAAQS, and data available to date for 2010 in EPA's Air Quality System (AQS) database that show the area continues to attain. If EPA finalizes this proposed determination of attainment, the requirements for the Area to submit attainment demonstrations and associated reasonably available control measures (RACM), a reasonable further progress (RFP) plan, contingency measures, and other planning State Implementation Plan (SIP) revisions related to attainment of the standard shall be suspended for so long as the Area continues to attain the annual PM2.5 NAAQS. Second, EPA is also proposing to determine, based on quality-assured and certified monitoring data for the 2007-2009 monitoring period, that the Area has attained the 1997 annual PM2.5 NAAQS by its applicable attainment date of April 5, 2010.

Using Baltimore HIV behavioral surveillance data for local HIV prevention planning.

PubMed

German, Danielle; Linton, Sabriya; Cassidy-Stewart, Hope; Flynn, Colin

2014-04-01

In response to the National HIV/AIDS Strategy (NHAS) and as part of CDC's Enhanced Comprehensive HIV Prevention Plan (ECHPP) project, Maryland developed a comprehensive local HIV prevention plan for the Baltimore-Towson Metropolitan Statistical Area and identified a series of priority HIV prevention and service goals. The current project sought to: (1) determine how well National HIV Behavioral Surveillance (NHBS) indicators were aligned with NHAS/ECHPP-informed local HIV prevention goals (2) facilitate on-going NHBS data utilization to inform on-going local HIV prevention and service planning, and (3) build a foundation for future NHBS data utilization in local HIV decision-making. Project activities identified key HIV-related indicators in NHBS that are directly or indirectly related to local HIV priorities as informed by NHAS/ECHPP, which can be used for HIV prevention planning in the Baltimore area. Areas for enhancing NHBS and local data collection to further inform HIV prevention priorities are highlighted.

An exploratory study of healthcare strategic planning in two metropolitan areas.

PubMed

Begun, James W; Kaissi, Amer A

2005-01-01

Little is known about empirical variation in the extent to which healthcare organizations conduct formal strategic planning or the extent to which strategic planning affects performance. Structural contingency and complexity science theory offer differing interpretations of the value of strategic planning. Structural contingency theory emphasizes adaptation to achieve organizational fit with a changing environment and views strategic planning as a way to chart the organization's path. Complexity science argues that planning is largely futile in changing environments. Interviews of leaders in 20 healthcare organizations in the metropolitan areas of Minneapolis/St. Paul, Minnesota, and San Antonio, Texas, reveal that strategic planning is a common and valued function in healthcare organizations. Respondents emphasized the need to continuously update strategic plans, involve physicians and the governing board, and integrate strategic plans with other organizational plans. Most leaders expressed that strategic planning contributes to organizational focus, fosters stakeholder participation and commitment, and leads to achievement of strategic goals. Because the widespread belief in strategic planning is based largely on experience, intuition, and faith, we present recommendations for developing an evidence base for healthcare strategic planning.

Assessing climate change-robustness of protected area management plans—The case of Germany

PubMed Central

Geyer, Juliane; Kreft, Stefan; Jeltsch, Florian; Ibisch, Pierre L.

2017-01-01

Protected areas are arguably the most important instrument of biodiversity conservation. To keep them fit under climate change, their management needs to be adapted to address related direct and indirect changes. In our study we focus on the adaptation of conservation management planning, evaluating management plans of 60 protected areas throughout Germany with regard to their climate change-robustness. First, climate change-robust conservation management was defined using 11 principles and 44 criteria, which followed an approach similar to sustainability standards. We then evaluated the performance of individual management plans concerning the climate change-robustness framework. We found that climate change-robustness of protected areas hardly exceeded 50 percent of the potential performance, with most plans ranking in the lower quarter. Most Natura 2000 protected areas, established under conservation legislation of the European Union, belong to the sites with especially poor performance, with lower values in smaller areas. In general, the individual principles showed very different rates of accordance with our principles, but similarly low intensity. Principles with generally higher performance values included holistic knowledge management, public accountability and acceptance as well as systemic and strategic coherence. Deficiencies were connected to dealing with the future and uncertainty. Lastly, we recommended the presented principles and criteria as essential guideposts that can be used as a checklist for working towards more climate change-robust planning. PMID:28982187

Appendix to project memorandum : metropolitan planning reviews : examples of MPO documentation

DOT National Transportation Integrated Search

1995-05-16

On November 26, 1991 Congress enacted the Intermodal Surface Transportation Efficiency Act of 1991 (ISTEA). This legislation mandates that Transportation Management Areas (urbanized areas with populations over 200,000) include as part of the planning...

A LAN Toolbox.

ERIC Educational Resources Information Center

Eddison, Elizabeth B.

1989-01-01

This bibliographic essay reviews sources that aid in the planning and management aspects of local area networks. Areas covered include system components; basic vocabularies; planning issues, including needs assessment, peripheral sharing alternatives and costs; and management issues, including purchasing, operating systems, installation, network…

An integrated regional planning/microsimulation model for the Buffalo/Niagara Falls area

DOT National Transportation Integrated Search

2010-04-01

This presentation examines the major planning issues facing the Buffalo and Niagara Falls area, which include freight, cross border congestion, and domestic issues. A Transportation Analysis and Simulation System (TRANSIMS) model is discussed that co...

76 FR 55643 - Helena National Forest; Montana; Divide Travel Plan EIS

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-08

... DEPARTMENT OF AGRICULTURE Forest Service Helena National Forest; Montana; Divide Travel Plan EIS... Divide travel planning area for wheeled and over-snow motorized vehicles. Consistent with Forest Service travel planning regulations, the designated wheeled motorized routes within the Divide Travel Planning...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saleh, H; Ferjani, S; Masssey, V

Purpose: Perform dosimetric comparison between planned and delivered dose in the junction area, measure daily dose variation in the arc junction area for pediatric patients treated for medulloblastoma using Craniospinal axis irradiation(CSI) Material and methods Dose comparison in the junction area, daily dose variation in the arc junction area for a Rando Phantom and 5 pediatric patients treated using CSI technique were analyzed. Plans were created using the Eclipse treatment planning system. Two arcs for cranium and 1 arc for spine region were used. Planar dose matrix was created by projecting phantom and patient plan into the ArcCheck phantom. EBT3more » film was placed in the middle of ArcCheck plug to measure dose distribution in the junction areaDuring patient treatment, strip of EBT3 film was placed daily at each junction area for verification. EBT3 films were scanned using a flatbed scanner, Epson Expression 10000 XL. Film QA pro software was used to analyze film. Scanning and analysis was performed according to vendor recommendations and AAPM TG-55 report. Films were scanned and analyzed daily after each treatment and at the end of treatment course. Planar dose distributions from films were compared with planar dose distribution from treatment planning system. Results: Comparison of planned vs. measured dose distributions for patients have passing rates of 90%–100% with 3% and 3 mm gamma analysis. In some of the treatment fractions, daily setup film showed variation in dose distribution in the junction area. Conclusion: It is critical to measure dose distribution in the arc junction area and use additional quality assurance measures to verify daily setup for CSI patient where one or more junctions are present. EBT3 film prove to be a good tool to achieve this task considering flexibility associated with the film such as symmetry, self-developing and ease of use.« less

A multi-modal approach to economic development in the metropolitan area transportation planning process

DOT National Transportation Integrated Search

2014-08-06

This white paper provides a review of research and current practices of integrating economic development goals in metropolitan area transportation planning. The information presented is intended to serve as a technical resource for transportation pla...

7 CFR 1940.959 - Area plan.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE (CONTINUED) PROGRAM REGULATIONS (CONTINUED) GENERAL System for Delivery of Certain Rural Development Programs § 1940.959 Area plan...

7 CFR 1940.959 - Area plan.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE (CONTINUED) PROGRAM REGULATIONS (CONTINUED) GENERAL System for Delivery of Certain Rural Development Programs § 1940.959 Area plan...

7 CFR 1940.959 - Area plan.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE (CONTINUED) PROGRAM REGULATIONS (CONTINUED) GENERAL System for Delivery of Certain Rural Development Programs § 1940.959 Area plan...

7 CFR 1940.959 - Area plan.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE (CONTINUED) PROGRAM REGULATIONS (CONTINUED) GENERAL System for Delivery of Certain Rural Development Programs § 1940.959 Area plan...

Des Moines metropolitan area ITS strategic plan

DOT National Transportation Integrated Search

1997-12-01

The purpose of this document is to report on the conclusions of the Intelligent Transportation Systems (ITS) Early Deployment Study (EDS) for the Des Moines metropolitan area. The objective of the study was to develop a strategic plan for the develop...

IDENTIFYING HIGH PRIORITY EXPOSURE RESEARCH SUPPORTING THE EPA ASBESTOS ACTION PLAN

EPA Science Inventory

The EPA Asbestos Action Plan outlines areas, including two exposure assessment areas, where research is needed to reduce uncertainties in current asbestos risk assessments. Scientists from the National Exposure Research Laboratory (NERL) recently conducted survey and literature ...

Transit development plan for the Yuma regional area

DOT National Transportation Integrated Search

1993-12-16

The purpose of this Transit Development Pan (TDP) is to indicate how transit could be implemented in the Yuma area, if and when, the local agencies decide to initiate public transit and utilize Federal Transit Administration (FTA) funds. The Plan dem...

Planning and Second Language Development in Task-Based Synchronous Computer-Mediated Communication

ERIC Educational Resources Information Center

Hsu, Hsiu-Chen

2012-01-01

This dissertation explored the effect of two planning conditions (the multiple planning condition with rehearsal and online planning time, and the single planning condition with online planning time only) on L2 production complexity and accuracy and the subsequent development of these two linguistic areas in the context of written synchronous…

Does Your Health Plan Measure Up? How Can You Tell?

ERIC Educational Resources Information Center

Edwards, Tom

1999-01-01

Describes the process behind health-plan selection for school district employees and offers suggestions on how managers might enhance their current healthcare plan purchasing process. Areas of health-plan review and critique are listed as are tips for measuring plan performance and advice on acquiring backup data on plan quality. (GR)

Year 2015 transportation plan : Huntsville Area Transportation Study

DOT National Transportation Integrated Search

1995-04-01

The Year 2015 Transportation Plan is an intermodal plan that considers all modes of the existing transportation system, identifies needs, provides policy direction and defines the goals for planning and : project development in the Huntsville urban a...

77 FR 67830 - Establishment of Sangre de Cristo Conservation Area, Colorado and New Mexico

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-14

... legislators throughout the planning process for the easement program. At the beginning of the planning process.../mountain-prairie/planning/ . FOR FURTHER INFORMATION CONTACT: Dr. Mike Dixon, Planning Team Leader, [[Page 67831

42 CFR 422.451 - Moratorium on new local preferred provider organization plans.

Code of Federal Regulations, 2010 CFR

2010-10-01

... for MA Regional Plans § 422.451 Moratorium on new local preferred provider organization plans. CMS... service area unless the MA organization seeking to offer the plan was offering a local preferred provider...

42 CFR 422.451 - Moratorium on new local preferred provider organization plans.

Code of Federal Regulations, 2011 CFR

2011-10-01

... for MA Regional Plans § 422.451 Moratorium on new local preferred provider organization plans. CMS... service area unless the MA organization seeking to offer the plan was offering a local preferred provider...

148. ARAIII Reactor building (ARA608) Floor plan. Shows location of ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

148. ARA-III Reactor building (ARA-608) Floor plan. Shows location of reactor, heater, and mechanical loop pits; mechanical and electrical equipment rooms; and other work areas. Aerojet-general 880-area/GCRE-608-A-1. Date: February 1958. Ineel index code no. 063-0608-00-013-102612. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

A&M. TAN607 second floor plan for cold assembly area. Metallurgical ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

A&M. TAN-607 second floor plan for cold assembly area. Metallurgical lab, chemistry lab, nuclear instrument lab, equipment rooms. Ralph M. Parsons 902-ANP-607-A 102. Date: December 1952. Approved by INEEL Classification Office for public release. INEEL index code no. 034-0607-693-106754 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

A&M. Plot plan of administration and A&M areas. Shows relationships ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

A&M. Plot plan of administration and A&M areas. Shows relationships among administration buildings and to A&M building (TAN-607), railroad turntable. Ralph M. Parsons 902-2&3-ANP-U 3. Date: December 1952. INEEL index code no. 032-0100-00-693-106690 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

Identifying appropriate protected areas for endangered fern species under climate change.

PubMed

Wang, Chun-Jing; Wan, Ji-Zhong; Zhang, Zhi-Xiang; Zhang, Gang-Min

2016-01-01

The management of protected areas (PAs) is widely used in the conservation of endangered plant species under climate change. However, studies that have identified appropriate PAs for endangered fern species are rare. To address this gap, we must develop a workflow to plan appropriate PAs for endangered fern species that will be further impacted by climate change. Here, we used endangered fern species in China as a case study, and we applied conservation planning software coupled with endangered fern species distribution data and distribution modeling to plan conservation areas with high priority protection needs under climate change. We identified appropriate PAs for endangered fern species under climate change based on the IUCN protected area categories (from Ia to VI) and planned additional PAs for endangered fern species. The high priority regions for protecting the endangered fern species were distributed throughout southern China. With decreasing temperature seasonality, the priority ranking of all endangered fern species is projected to increase in existing PAs. Accordingly, we need to establish conservation areas with low climate vulnerability in existing PAs and expand the conservation areas for endangered fern species in the high priority conservation regions.

Accommodating Dynamic Oceanographic Processes and Pelagic Biodiversity in Marine Conservation Planning

PubMed Central

Grantham, Hedley S.; Game, Edward T.; Lombard, Amanda T.; Hobday, Alistair J.; Richardson, Anthony J.; Beckley, Lynnath E.; Pressey, Robert L.; Huggett, Jenny A.; Coetzee, Janet C.; van der Lingen, Carl D.; Petersen, Samantha L.; Merkle, Dagmar; Possingham, Hugh P.

2011-01-01

Pelagic ecosystems support a significant and vital component of the ocean's productivity and biodiversity. They are also heavily exploited and, as a result, are the focus of numerous spatial planning initiatives. Over the past decade, there has been increasing enthusiasm for protected areas as a tool for pelagic conservation, however, few have been implemented. Here we demonstrate an approach to plan protected areas that address the physical and biological dynamics typical of the pelagic realm. Specifically, we provide an example of an approach to planning protected areas that integrates pelagic and benthic conservation in the southern Benguela and Agulhas Bank ecosystems off South Africa. Our aim was to represent species of importance to fisheries and species of conservation concern within protected areas. In addition to representation, we ensured that protected areas were designed to consider pelagic dynamics, characterized from time-series data on key oceanographic processes, together with data on the abundance of small pelagic fishes. We found that, to have the highest likelihood of reaching conservation targets, protected area selection should be based on time-specific data rather than data averaged across time. More generally, we argue that innovative methods are needed to conserve ephemeral and dynamic pelagic biodiversity. PMID:21311757

Northwest Forest Plan—the first 10 years (1994–2003): preliminary assessment of the condition of watersheds.

Treesearch

Kirsten Gallo; Steven H. Lanigan; Peter Eldred; Sean N. Gordon; Chris Moyer

2005-01-01

We aggregated road, vegetation, and inchannel data to assess the condition of sixth-field watersheds and describe the distribution of the condition of watersheds in the Northwest Forest Plan (the Plan) area. The assessment is based on 250 watersheds selected at random within the Plan area. The distributions of conditions are presented for watersheds and for many of the...

Maritime Strike Operations Tactics Development and Evaluation, Eglin Air Force Base, Florida. Final Environmental Assessment

DTIC Science & Technology

2013-05-01

Regulation The Proposed Action would not affect local government comprehensive plans. Requires local governments to prepare, adopt, and implement...state-level planning efforts. Requires the development of special statewide plans governing water use, land development, and transportation...cleared area in state waters. However, avoidance of this area would not be significantly burdensome for tourists or recreational users of the Gulf, as

Estimating family planning program effects on U.S. fertility rates.

PubMed

Cutright, P; Jaffe, F S

1977-08-01

An evaluation was undertaken of the effects on U. S. fertility rates of the national family planning program. 1968-1969 family planning enrollment data were linked to 1970 census data in the same areas to derive an objective measure of the impact of organized clinical family planning programs on the 1969-70 fertility rates of subgroups of women defined by age, race, marital status, economic status, and racial composition of their area. Multivariate modelling was used to control for spurious effects of irrelevant variables. Results of the multivariate modelling show significant reductions of marital fertility among the low socioeconomic groups served by the program; no effects were exhibited by groups not served. Cumulative fertility of all groups, black and white, at all age and socioeconomic levels was affected by the program. A plausible explanation for these results lies in antecedent factors which led to the presence or absence of family planning clinics in any particular area in 1969 and its 1969 enrollment level. Communities more favorably disposed to provision of birth control services would have been more likely than other areas to apply for federal funding of family planning programs when it became available in the middle 1960s. Due to an earlier start, their programs were flourishing by 1969.

36 CFR 910.59 - Development parcel.

Code of Federal Regulations, 2010 CFR

2010-07-01

... GUIDELINES AND UNIFORM STANDARDS FOR URBAN PLANNING AND DESIGN OF DEVELOPMENT WITHIN THE PENNSYLVANIA AVENUE... goals of comprehensive planning and design for that particular coordinated planning area. ...

36 CFR 910.59 - Development parcel.

Code of Federal Regulations, 2011 CFR

2011-07-01

... GUIDELINES AND UNIFORM STANDARDS FOR URBAN PLANNING AND DESIGN OF DEVELOPMENT WITHIN THE PENNSYLVANIA AVENUE... goals of comprehensive planning and design for that particular coordinated planning area. ...

75 FR 66718 - Helena National Forest; Montana; Blackfoot Travel Plan EIS

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-29

... DEPARTMENT OF AGRICULTURE Forest Service Helena National Forest; Montana; Blackfoot Travel Plan... within the Blackfoot travel planning area. Consistent with the Forest Service travel planning regulations.... Please indicate the name ``Blackfoot Travel Plan'' in the subject line of your e-mail. FOR FURTHER...

Field sampling and analysis plan for the remedial investigation of Waste Area Grouping 2 at Oak Ridge National Laboratory, Oak Ridge, Tennessee. Environmental Restoration Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boston, H.L.; Ashwood, T.L.; Borders, D.M.

1992-02-01

This field sampling and analysis (S & A) plan has been developed as part of the Department of Energy`s (DOE`s) remedial investigation (RI) of Waste Area Grouping (WAG) 2 at Oak Ridge National Laboratory (ORNL) located in Oak Ridge, Tennessee. The S & A plan has been written in support of the remedial investigation (RI) plan for WAG 2 (ORNL 1990). WAG 2 consists of White Oak Creek (WOC) and its tributaries downstream of the ORNL main plant area, White Oak Lake (WOL), White Oak Creek embayment (WOCE) on the Clinch River, and the associated floodplain and subsurface environment (Fig.more » 1.1). The WOC system is the surface drainage for the major ORNL WAGs and has been exposed to a diversity of contaminants from operations and waste disposal activities in the WOC watershed. WAG 2 acts as a conduit through which hydrologic fluxes carry contaminants from upgradient areas to the Clinch River. Water, sediment, soil, and biota in WAG 2 are contaminated and continue to receive contaminants from upgradient WAGs. This document describes the following: an overview of the RI plan, background information for the WAG 2 system, and objectives of the S & A plan; the scope and implementation of the first 2 years of effort of the S & A plan and includes recent information about contaminants of concern, organization of S & A activities, interactions with other programs, and quality assurance specific to the S & A activities; provides details of the field sampling plans for sediment, surface water, groundwater, and biota, respectively; and describes the sample tracking and records management plan.« less

Integration of Functional Magnetic Resonance Imaging and Magnetoencephalography Functional Maps Into a CyberKnife Planning System: Feasibility Study for Motor Activity Localization and Dose Planning.

PubMed

De Martin, Elena; Duran, Dunja; Ghielmetti, Francesco; Visani, Elisa; Aquino, Domenico; Marchetti, Marcello; Sebastiano, Davide Rossi; Cusumano, Davide; Bruzzone, Maria Grazia; Panzica, Ferruccio; Fariselli, Laura

2017-12-01

Magnetoencephalography (MEG) and functional magnetic resonance imaging (fMRI) provide noninvasive localization of eloquent brain areas for presurgical planning. The aim of this study is the integration of MEG and fMRI maps into a CyberKnife (CK) system to optimize dose planning. Four patients with brain metastases in the motor area underwent functional imaging study of the hand motor cortex before radiosurgery. MEG data were acquired during a visually cued hand motor task. Motor activations were identified also using an fMRI block-designed paradigm. MEG and fMRI maps were then integrated into a CK system and contoured as organs at risk for treatment planning optimization. The integration of fMRI data into the CK system was achieved for all patients by means of a standardized protocol. We also implemented an ad hoc pipeline to convert the MEG signal into a DICOM standard, to make sure that it was readable by our CK treatment planning system. Inclusion of the activation areas into the optimization plan allowed the creation of treatment plans that reduced the irradiation of the motor cortex yet not affecting the brain peripheral dose. The availability of advanced neuroimaging techniques is playing an increasingly important role in radiosurgical planning strategy. We successfully imported MEG and fMRI activations into a CK system. This additional information can improve dose sparing of eloquent areas, allowing a more comprehensive investigation of the related dose-volume constraints that in theory could translate into a gain in tumor local control, and a reduction of neurological complications. Copyright © 2017 Elsevier Inc. All rights reserved.

Corrective Action Decision Document/Corrective Action Plan for the 92-Acre Area and Corrective Action Unit 111: Area 5 WMD Retired Mixed Waste Pits, Nevada National Security Site, Nevada

DOE Office of Scientific and Technical Information (OSTI.GOV)

NSTec Environmental Restoration

This Corrective Action Decision Document/Corrective Action Plan (CADD/CAP) has been prepared for the 92-Acre Area, the southeast quadrant of the Radioactive Waste Management Site, located in Area 5 of the Nevada National Security Site (NNSS). The 92-Acre Area includes Corrective Action Unit (CAU) 111, 'Area 5 WMD Retired Mixed Waste Pits.' Data Quality Objectives (DQOs) were developed for the 92-Acre Area, which includes CAU 111. The result of the DQO process was that the 92-Acre Area is sufficiently characterized to provide the input data necessary to evaluate corrective action alternatives (CAAs) without the collection of additional data. The DQOs aremore » included as Appendix A of this document. This CADD/CAP identifies and provides the rationale for the recommended CAA for the 92-Acre Area, provides the plan for implementing the CAA, and details the post-closure plan. When approved, this CADD/CAP will supersede the existing Pit 3 (P03) Closure Plan, which was developed in accordance with Title 40 Code of Federal Regulations (CFR) Part 265, 'Interim Status Standards for Owners and Operators of Hazardous Waste Treatment, Storage, and Disposal Facilities.' This document will also serve as the Closure Plan and the Post-Closure Plan, which are required by 40 CFR 265, for the 92-Acre Area. After closure activities are complete, a request for the modification of the Resource Conservation and Recovery Act Permit that governs waste management activities at the NNSS will be submitted to the Nevada Division of Environmental Protection to incorporate the requirements for post-closure monitoring. Four CAAs, ranging from No Further Action to Clean Closure, were evaluated for the 92-Acre Area. The CAAs were evaluated on technical merit focusing on performance, reliability, feasibility, safety, and cost. Based on the evaluation of the data used to develop the conceptual site model; a review of past, current, and future operations at the site; and the detailed and comparative analysis of the potential CAAs, Closure in Place with Administrative Controls is the preferred CAA for the 92-Acre Area. Closure activities will include the following: (1) Constructing an engineered evapotranspiration cover over the 92-Acre Area; (2) Installing use restriction (UR) warning signs, concrete monuments, and subsidence survey monuments; (3) Establishing vegetation on the cover; (4) Implementing a UR; and (5) Implementing post-closure inspections and monitoring. The Closure in Place with Administrative Controls alternative meets all requirements for the technical components evaluated, fulfills all applicable federal and state regulations for closure of the site, and will minimize potential future exposure pathways to the buried waste at the site.« less

Corrective Action Decision Document/Corrective Action Plan for the 92-Acre Area and Corrective Action Unit 111: Area 5 WMD Retired Mixed Waste Pits, Nevada Test Site, Nevada

DOE Office of Scientific and Technical Information (OSTI.GOV)

NSTec Environmental Restoration

2009-07-31

This Corrective Action Decision Document/Corrective Action Plan (CADD/CAP) has been prepared for the 92-Acre Area, the southeast quadrant of the Radioactive Waste Management Site, located in Area 5 of the Nevada Test Site (NTS). The 92-Acre Area includes Corrective Action Unit (CAU) 111, 'Area 5 WMD Retired Mixed Waste Pits.' Data Quality Objectives (DQOs) were developed for the 92-Acre Area, which includes CAU 111. The result of the DQO process was that the 92-Acre Area is sufficiently characterized to provide the input data necessary to evaluate corrective action alternatives (CAAs) without the collection of additional data. The DQOs are includedmore » as Appendix A of this document. This CADD/CAP identifies and provides the rationale for the recommended CAA for the 92-Acre Area, provides the plan for implementing the CAA, and details the post-closure plan. When approved, this CADD/CAP will supersede the existing Pit 3 (P03) Closure Plan, which was developed in accordance with Title 40 Code of Federal Regulations (CFR) Part 265, 'Interim Status Standards for Owners and Operators of Hazardous Waste Treatment, Storage, and Disposal Facilities.' This document will also serve as the Closure Plan and the Post-Closure Plan, which are required by 40 CFR 265, for the 92-Acre Area. After closure activities are complete, a request for the modification of the Resource Conservation and Recovery Act Permit that governs waste management activities at the NTS will be submitted to the Nevada Division of Environmental Protection to incorporate the requirements for post-closure monitoring. Four CAAs, ranging from No Further Action to Clean Closure, were evaluated for the 92-Acre Area. The CAAs were evaluated on technical merit focusing on performance, reliability, feasibility, safety, and cost. Based on the evaluation of the data used to develop the conceptual site model; a review of past, current, and future operations at the site; and the detailed and comparative analysis of the potential CAAs, Closure in Place with Administrative Controls is the preferred CAA for the 92-Acre Area. Closure activities will include the following: (1) Constructing an engineered evapotranspiration cover over the 92-Acre Area; (2) Installing use restriction (UR) warning signs, concrete monuments, and subsidence survey monuments; (3) Establishing vegetation on the cover; (4) Implementing a UR; and (5) Implementing post-closure inspections and monitoring. The Closure in Place with Administrative Controls alternative meets all requirements for the technical components evaluated, fulfills all applicable federal and state regulations for closure of the site, and will minimize potential future exposure pathways to the buried waste at the site.« less

Oil and gas resources of the Cheat Mountain Further Planning Area (Rare II), Randolph County, West Virginia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weed, E.G.A.

1981-01-01

This map presents an analysis of the oil and gas resources of the Cheat Mountain Further Planning Area in the Monomgahela National Forest, Randolph County, West Virgina. 28 references, 4 figures, 1 table.

77 FR 61021 - Notice of Intent To Prepare a Resource Management Plan Amendment and Associated Environmental...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-05

... Wilderness in Red Rock Canyon National Conservation Area, Clark County, NV AGENCY: Bureau of Land Management... designated as wilderness and are no longer WSAs governed by the IMP. The planning area is located in Clark...

The First International Biosphere Reserve Congress.

ERIC Educational Resources Information Center

Laird, John

1984-01-01

Presents objectives (and related activities) of a plan designed for international collaboration in conserving key natural areas (biosphere reserves) of the globe. The plan (focusing on such areas as management, conservation, research, monitoring, and environmental education/training) was formulated during the First International Biosphere Reserve…

Grand Forks/East Grand Forks ITS strategy plan

DOT National Transportation Integrated Search

2001-01-15

The Grand Forks/East Grand Forks (GF/EGF) Area's Intelligent Transportation Systems (ITS) Strategy Plan is an effort by the GF/EGF Metropolitan Planning Organization (MPO) and its partners to develop a plan for deploying Intelligent Transportation Sy...

7 CFR 1751.101 - General.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE TELECOMMUNICATIONS SYSTEM PLANNING AND DESIGN CRITERIA, AND PROCEDURES State Telecommunications Modernization Plan... Plan must, at a minimum, apply to RUS Borrowers' wireline service areas. If a Modernization Plan is...

The Effect of Area HMO Market Share on Cancer Screening

PubMed Central

Baker, Laurence C; Phillips, Kathryn A; Haas, Jennifer S; Liang, Su-Ying; Sonneborn, Dean

2004-01-01

Objective Managed care may have widespread impacts on health care delivery for all patients in the areas where they operate. We examine the relationship between area managed care activity and screening for breast, cervical, and prostate cancer among patients enrolled in more managed care plans and patients who are enrolled in less managed plans. Data and Methods Data on cancer screening from the 1996 Medical Expenditure Panel Survey (MEPS) were linked to data on health maintenance organization (HMO) and preferred provider organization (PPO) market share and HMO competition at the metropolitan statistical area (MSA) level. Logistic regression analysis was used to examine the relationship between area managed care prevalence and the use of mammography, clinical breast examination, Pap smear, and prostate cancer screening in the past two years, controlling for important covariates. Results Among all patients, increases in area-level HMO market share are associated with increases in the appropriate use of mammography, clinical breast exam, and Pap smear (OR for high relative to low managed care areas are 1.75, p<.01, for mammography, 1.58, p<.05, for clinical breast exam, and 1.71, p<.01, for Pap smear). In analyses of subgroups, the relationship is significant only for individuals who are enrolled in the nonmanaged plans; there is no relationship for individuals in more managed plans. No relationship is observed between area HMO market share and prostate cancer screening in any analysis. Neither the level of competition between area HMOs nor area PPO market share is associated with screening rates. Conclusions Area-level managed care activity can influence preventive care treatment patterns. PMID:15533185

7 CFR 1948.78 - Growth management and housing planning projects.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 13 2010-01-01 2009-01-01 true Growth management and housing planning projects. 1948... Impacted Area Development Assistance Program § 1948.78 Growth management and housing planning projects. (a) Existing plans for growth management and housing may be used to meet the planning requirements of this...

77 FR 46518 - Draft Resource Management Plan/General Plan Draft Environmental Impact Statement/Revised Draft...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-03

... DEPARTMENT OF THE INTERIOR Bureau of Reclamation Draft Resource Management Plan/General Plan Draft... Recreation Area, Merced County, California AGENCY: Bureau of Reclamation, Interior. ACTION: Notice of... California Department of Parks and Recreation was given the responsibility to plan, design, construct...

36 CFR 910.11 - Comprehensive urban planning and design.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Comprehensive urban planning... CORPORATION GENERAL GUIDELINES AND UNIFORM STANDARDS FOR URBAN PLANNING AND DESIGN OF DEVELOPMENT WITHIN THE PENNSYLVANIA AVENUE DEVELOPMENT AREA Urban Planning and Design Concerns § 910.11 Comprehensive urban planning...

7 CFR 1948.78 - Growth management and housing planning projects.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 13 2013-01-01 2013-01-01 false Growth management and housing planning projects. 1948... Impacted Area Development Assistance Program § 1948.78 Growth management and housing planning projects. (a) Existing plans for growth management and housing may be used to meet the planning requirements of this...

7 CFR 1948.78 - Growth management and housing planning projects.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 13 2012-01-01 2012-01-01 false Growth management and housing planning projects. 1948... Impacted Area Development Assistance Program § 1948.78 Growth management and housing planning projects. (a) Existing plans for growth management and housing may be used to meet the planning requirements of this...

7 CFR 1948.78 - Growth management and housing planning projects.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 13 2011-01-01 2009-01-01 true Growth management and housing planning projects. 1948... Impacted Area Development Assistance Program § 1948.78 Growth management and housing planning projects. (a) Existing plans for growth management and housing may be used to meet the planning requirements of this...

7 CFR 1948.78 - Growth management and housing planning projects.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 13 2014-01-01 2013-01-01 true Growth management and housing planning projects. 1948... Impacted Area Development Assistance Program § 1948.78 Growth management and housing planning projects. (a) Existing plans for growth management and housing may be used to meet the planning requirements of this...

ACHP | News

Science.gov Websites

Landscapes Action Plan emphasizes consultation early in project planning and identification of areas of Cultural Landscapes Forum Provides Action Plan Theresa Pasqual and Kevin Cannell participate in the forum

An implementation plan for priorities in solar-system space physics

NASA Technical Reports Server (NTRS)

Krimigis, Stamatios M.; Athay, R. Grant; Baker, Daniel; Fisk, Lennard A.; Fredricks, Robert W.; Harvey, John W.; Jokipii, Jack R.; Kivelson, Margaret; Mendillo, Michael; Nagy, Andrew F.

1985-01-01

The scientific objectives and implementation plans and priorities of the Space Science Board in areas of solar physics, heliospheric physics, magnetospheric physics, upper atmosphere physics, solar-terrestrial coupling, and comparative planetary studies are discussed and recommended programs are summarized. Accomplishments of Skylab, Solar Maximum Mission, Nimbus-7, and 11 other programs are highlighted. Detailed mission plans in areas of solar and heliospheric physics, plasma physics, and upper atmospheric physics are also described.

Guidelines for the Planning of Rural Areas in Europe. A Contribution to an Overall European Regional Planning Policy. Conference Report Presented by the Belgian and German Delegations.

ERIC Educational Resources Information Center

Council of Europe, Strasbourg (France).

Rural regional planning that will satisfy man's real needs, and not merely those of an economic nature, must take into consideration all factors, all possible interactions, and most important of all, those values which cannot be expressed in terms of money. The report details the functions and problems of rural areas revealed by analyses of rural…

The Use of Multi-Criteria Evaluation and Network Analysis in the Area Development Planning Process

DTIC Science & Technology

2013-03-01

layouts. The alternative layout scoring process, base in multi-criteria evaluation, returns a quantitative score for each alternative layout and a...The purpose of this research was to develop improvements to the area development planning process. These plans are used to improve operations within...an installation sub-section by altering the physical layout of facilities. One methodology was developed based on apply network analysis concepts to

40 CFR 51.918 - Can any SIP planning requirements be suspended in 8-hour ozone nonattainment areas that have air...

Code of Federal Regulations, 2013 CFR

2013-07-01

... suspended in 8-hour ozone nonattainment areas that have air quality data that meets the NAAQS? 51.918... 8-hour Ozone National Ambient Air Quality Standard § 51.918 Can any SIP planning requirements be suspended in 8-hour ozone nonattainment areas that have air quality data that meets the NAAQS? Upon a...

40 CFR 51.918 - Can any SIP planning requirements be suspended in 8-hour ozone nonattainment areas that have air...

Code of Federal Regulations, 2011 CFR

2011-07-01

... suspended in 8-hour ozone nonattainment areas that have air quality data that meets the NAAQS? 51.918... 8-hour Ozone National Ambient Air Quality Standard § 51.918 Can any SIP planning requirements be suspended in 8-hour ozone nonattainment areas that have air quality data that meets the NAAQS? Upon a...

13. "CIVIL, SITE PLAN AND VICINITY MAP, AREA LOCATIONS." Test ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. "CIVIL, SITE PLAN AND VICINITY MAP, AREA LOCATIONS." Test Area 1-125. Specifications No. ENG (NASA)-04-35363-1; Drawing No. 60-09-34; sheet 11. Ref. No. C-l. D.O. SERIES 1597/1. Approved for siting on 24 April 1962. - Edwards Air Force Base, Air Force Rocket Propulsion Laboratory, Leuhman Ridge near Highways 58 & 395, Boron, Kern County, CA

143. ARAIII Control building (ARA607) Floor plan. Shows control room, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

143. ARA-III Control building (ARA-607) Floor plan. Shows control room, contaminated work area, counting and computer room, health physics room, instrument repair room, offices, and other rooms. Aerojet-general 880-area/GCRE-607-A-1. Date: February 1958. Ineel index code no. 063-0607-00-013-102546. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

SPERTI Gate House at control area (PER603). Floor plan, elevations, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

SPERT-I Gate House at control area (PER-603). Floor plan, elevations, sections. This Gate House replaced the original gate house, for which drawings are no longer extant. F.C. Torkelson 842-SPERT-603-A-1. Date: February 1962. INEEL index no. 760-0603-00-851-151336 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

A Developmental Curriculum Plan To Achieve a Sequenced Curriculum between High School Courses in Food Preparation and the Mattatuck Community College Hospitality/Food Services Program. Final Report.

ERIC Educational Resources Information Center

Mattatuck Community Coll., Waterbury, CT.

This document contains a developmental curriculum plan for an articulated curriculum in hospitality/food service for Connecticut's Mattatuck Community College and area high schools. The curriculum guide includes a course description, criteria for evaluation, attendance policy, objectives, a curriculum area outline, 17 content area objectives, a…

Trajectory Generation and Path Planning for Autonomous Aerobots

NASA Technical Reports Server (NTRS)

Sharma, Shivanjli; Kulczycki, Eric A.; Elfes, Alberto

2007-01-01

This paper presents global path planning algorithms for the Titan aerobot based on user defined waypoints in 2D and 3D space. The algorithms were implemented using information obtained through a planner user interface. The trajectory planning algorithms were designed to accurately represent the aerobot's characteristics, such as minimum turning radius. Additionally, trajectory planning techniques were implemented to allow for surveying of a planar area based solely on camera fields of view, airship altitude, and the location of the planar area's perimeter. The developed paths allow for planar navigation and three-dimensional path planning. These calculated trajectories are optimized to produce the shortest possible path while still remaining within realistic bounds of airship dynamics.

Facilities Planning Guide for the Community College System.

ERIC Educational Resources Information Center

Massachusetts Advisory Council on Education, Boston.

These guidelines include definitions pertaining to educational criteria and planning criteria, and guidelines regarding--(1) administrative ratios, (2) space allocation in assignable square feet, (3) area conversion factors, (4) gross building area distribution, (5) curriculum balance development, (6) project performance schedule, and (7) project…

Engineering Technology Programs. Preliminary Curriculum Planning Guide.

ERIC Educational Resources Information Center

Center for Occupational Research and Development, Inc., Waco, TX.

Developed as a resource to assist in a major revision underway in Georgia area technical schools to change curricula for preparing engineering technicians, this preliminary program-planning guide describes curriculum structures for specialized programs in three major areas--electronics, electromechanics, and mechanics. The handbook, which is…

36 CFR 294.28 - Scope and applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

... this subpart shall take precedence over any inconsistent land management plan component. Land management plan components that are not inconsistent with this subpart will continue to provide guidance for... SPECIAL AREAS Idaho Roadless Area Management § 294.28 Scope and applicability. (a) After October 16, 2008...

23 CFR 450.312 - Metropolitan planning area boundaries.

Code of Federal Regulations, 2010 CFR

2010-04-01

... responsibility for a portion of the multistate area, MPO(s), and the public transportation operator(s) are... (in cooperation with the State and public transportation operator(s)) to determine if existing MPA... 450.312 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH...

13. Photograph of a line drawing. 'BUILDING LOCATION PLAN, AREAS ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

13. Photograph of a line drawing. 'BUILDING LOCATION PLAN, AREAS A & B.' Holston Army Ammunition Plant, Holston Defense Corporation. September 8, 1970. Delineator: R. C. G. Drawing # 7651-212/1226.03. - Holston Army Ammunition Plant, Producer Gas Plant, Kingsport, Sullivan County, TN

36 CFR 292.63 - Plan of operations-supplementary requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false Plan of operations-supplementary requirements. 292.63 Section 292.63 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL RECREATION AREAS Smith River National Recreation Area Locatable Minerals...

36 CFR 292.63 - Plan of operations-supplementary requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 36 Parks, Forests, and Public Property 2 2013-07-01 2013-07-01 false Plan of operations-supplementary requirements. 292.63 Section 292.63 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL RECREATION AREAS Smith River National Recreation Area Locatable Minerals...

36 CFR 292.63 - Plan of operations-supplementary requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false Plan of operations-supplementary requirements. 292.63 Section 292.63 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL RECREATION AREAS Smith River National Recreation Area Locatable Minerals...

36 CFR 292.63 - Plan of operations-supplementary requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false Plan of operations-supplementary requirements. 292.63 Section 292.63 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL RECREATION AREAS Smith River National Recreation Area Locatable Minerals...

10 CFR 60.17 - Contents of site characterization plan.

Code of Federal Regulations, 2010 CFR

2010-01-01

... GEOLOGIC REPOSITORIES Licenses Preapplication Review § 60.17 Contents of site characterization plan. The... construction authorization for a geologic repository operations area; (4) Criteria, developed pursuant to... area for the location of a geologic repository; and (5) Any other information which the Commission, by...

ARCHITECTURAL FLOOR PLAN OF OPERATING AREA HOT PILOT PLANT (CPP640). ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

ARCHITECTURAL FLOOR PLAN OF OPERATING AREA HOT PILOT PLANT (CPP-640). INL DRAWING NUMBER 200-0640-00-279-111678. ALTERNATE ID NUMBER 8952-CPP-640-A-1. - Idaho National Engineering Laboratory, Idaho Chemical Processing Plant, Fuel Reprocessing Complex, Scoville, Butte County, ID

Area XV Career Education Research & Planning. Final Report.

ERIC Educational Resources Information Center

Indian Hills Community Coll., Ottumwa, IA.

Critical issues in career education are addressed in this report of an advisory committee seeking input and making recommendations for career education implementation in Iowa. Recommendations addressing state, area, and local school district responsibilities are grouped into three main perspectives: planning, implementation, and evaluation. The…

36 CFR 292.63 - Plan of operations-supplementary requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Plan of operations-supplementary requirements. 292.63 Section 292.63 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE NATIONAL RECREATION AREAS Smith River National Recreation Area Locatable Minerals...

7 CFR 1781.4 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... improvement. (d) RC&D measure plan. A plan document for a land area, directly controlled or under the... area. (f) Watershed works of improvement. Structural, nonstructural, and land treatment measures... costs of installing WS works of improvement or RCD measures by the Federal Government and by sponsoring...

7 CFR 1781.4 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... improvement. (d) RC&D measure plan. A plan document for a land area, directly controlled or under the... area. (f) Watershed works of improvement. Structural, nonstructural, and land treatment measures... costs of installing WS works of improvement or RCD measures by the Federal Government and by sponsoring...