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Sample records for arengusuunad aastateks 2007-2013

  1. Imported malaria in children in Madrid, Spain, 2007-2013.

    PubMed

    Sánchez, Beatriz Soto; Tato, L M Prieto; Martín, S Guillén; Pérez, E; Grasa, C; Valderrama, S; Augusto, I de; Sierra, M; Ros, M García; Aguado, I; Hortelano, M García López

    The majority of malaria cases diagnosed in Europe in the last few years have occurred in people living in non-endemic areas travelling back to their home country to visit friends and relatives (VFRs). Children account for 15-20% of imported malaria, with known higher risk of severe disease. A retrospective multicentre study was conducted in 24 hospitals in Madrid (Spain) including patients under 16 years diagnosed with malaria (2007-2013). A total of 149 episodes in 147 children were reported. Plasmodium falciparum was the species most commonly isolated. Twenty-five patients developed severe malaria and there was one death related to malaria. VFR accounted for 45.8% of our children. Only 17 VFRs had received prophylaxis, and 4 of them taken appropriately. They presented more frequently with fever (98% vs. 69%), a longer time with fever (55 vs. 26%), delay in diagnosis of more than three days (62 vs. 37%), and more thrombocytopenia (65 vs. 33%) than non-VFRs, and with significant differences (p<0.05). VFRs represent a large proportion of imported malaria cases in our study. They seldom took adequate prophylaxis, and delayed the visit to the physician, increasing the length of fever and subsequent delaying in diagnosis. Appropriate preventive measures, such as education and pre-travel advices should be taken in this population. Copyright © 2016 Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  2. Content Analysis of Papers Submitted to "Communications in Information Literacy," 2007-2013

    ERIC Educational Resources Information Center

    Hollister, Christopher V.

    2014-01-01

    The author conducted a content analysis of papers submitted to the journal, "Communications in Information Literacy," from the years 2007-2013. The purpose was to investigate and report on the overall quality characteristics of a statistically significant sample of papers submitted to a single-topic, open access, library and information…

  3. Space-time scan statistics of 2007-2013 dengue incidence in Cimahi City, Indonesia.

    PubMed

    Dhewantara, Pandji Wibawa; Ruliansyah, Andri; Fuadiyah, M Ezza Azmi; Astuti, Endang Puji; Widawati, Mutiara

    2015-11-27

    Four dengue serotypes threatened more than 200 million people and has spread to over 400 districts in Indonesia. Furthermore, 26 districts in most densely populated province, West Java, have been declared as hyperendemic areas. Cimahi is an endemic city with the highest population (14,969 people per square kilometer). Evidence on distribution pattern of dengue cases is required to discover the spread of dengue cases in Cimahi. A study has been conducted to detect clusters of dengue incidence during 2007-2013. A temporal spatial analysis was performed using SaTScan™ software incorporated confirmed dengue monthly data from the Municipality Health Office and population data from a local Bureau of Statistics. A retrospective space-time analysis with a Poisson distribution model and monthly precision was performed. Our results revealed a significant most likely cluster (p<0.001) throughout period of study. The most likely cluster was detected in the centre of the city and moved to the northern region of Cimahi. Cimahi, Karangmekar, and Cibabat village were most likely cluster in 2007-2010 (p <0.001; RR = 2.16-2.98; pop at risk 12% total population); Citeureup were detected as the most likely cluster in 2011-2013 (p <0.001; RR 5.77), respectively. Temporaly, clusters were detected in the first quarter of each year each. In conclusion, a dynamic spread of dengue initiated from the centre to its surrounding areas during the period 2007-2013. Our study suggests the use of GIS to strengthen case detection and surveillance. An in-depth investigation to relevant risk factors in high-risk areas in Cimahi city is encouraged.

  4. The observation of crustal deformation derived from Taiwan Continuous GPS Array (2007-2013)

    NASA Astrophysics Data System (ADS)

    Min-Chien, Tsai; Shui-Beih, Yu; Tzay-Chyn, Shin

    2015-04-01

    Data collected by 281 sites of Taiwan Continuous GPS Array from 2007 to 2013 are processed with GAMIT/GLOBK software. The acquired GPS position time series are described by model parameters such as linear rate, annual and semi-annual periodic motions, coseismic offsets, postseismic rate change, and exponential decay after earthquakes. Stacking of power spectral densities from 281 continuous GPS data in Taiwan, we found the slopes of spectra (spectral index) are -0.72, -0.77, and -0.57 for the E, N, U components, respectively. It indicates the errors of continuous GPS data can be described as a combination of white noise and flicker noise. The common-mode errors are removed by stacking data from 50 continuous GPS sites with data period more than 5 years. By removing common-mode errors, the precision of GPS data is further improved to 2.3 mm, 1.9 mm, and 6.9 mm in the E, N, U components, respectively. After strictly data quality control, time series analysis and noise analysis, we derive a new ITRF2008 velocity field and velocity field relative to Penghu using GPS data from 2007 to 2013 in the Taiwan area. The general pattern of the newly derived 2007-2013 velocity field is quite similar with that from previous studies, but the station density is much larger and spatial coverage is better, too. About 80 mm/yr plate convergence rate is observed, approximately half of plate convergence rate is accommodated on the fold and thrust belt of western Taiwan and another half is taken up in the Longitudinal Valley and the Coastal Range in eastern Taiwan. The velocities in western Taiwan generally show a fan-shaped pattern, consistent with the direction of maximum compression tectonic stress. In northern Taiwan, the velocity vectors reveal clockwise rotation, indicating the on-going extensional deformation related to the back-arc extension of the Okinawa Trough. In southern Taiwan, the horizontal velocity increases from about 40 mm/yr at Chiayi-Tainan to 55 mm/yr in the

  5. Survey and habitat data for postbreeding lesser scaup, Lower Red Rock Lake, MT, 2007-2013

    USGS Publications Warehouse

    Austin, Jane E.; Warren, Jeffrey

    2016-01-01

    The data are part of a larger, long-term project of lesser scaup on Lower Red Rock Lake, Montana, 2004-2015, conducted by the US Fish and Wildlife Service. This segment of the data has summarized results of late summer resighting surveys of nasal-marked adult females and GIS-derived habitat attributes. Scaup resighting surveys were conducted mid-August to early September, 2007-2013. The study site was divided into 16 survey plots (as shown as grid in figure); each plot comprised one to four 750 × 750 m survey blocks such that plots contained roughly equivalent area of open water Survey data included GPS location, number, and social status of marked females, wind conditions, and group size of other scaup associated with a marked bird. Each record is one resight session. Habitat attributes were derived from annual lake-level data (water depth) and analyses of 2008 aerial imagery (percent open area, viewshed, interface of water:emergent vegetation, percent bare aquatic substrate, fetch distance). Both types of GIS data were delineated at the cell (quarter-block) scale (375 x 375m).

  6. Risk for Low Pathogenicity Avian Influenza Virus on Poultry Farms, the Netherlands, 2007-2013.

    PubMed

    Bouwstra, Ruth; Gonzales, Jose L; de Wit, Sjaak; Stahl, Julia; Fouchier, Ron A M; Elbers, Armin R W

    2017-09-01

    Using annual serologic surveillance data from all poultry farms in the Netherlands during 2007-2013, we quantified the risk for the introduction of low pathogenicity avian influenza virus (LPAIV) in different types of poultry production farms and putative spatial-environmental risk factors: distance from poultry farms to clay soil, waterways, and wild waterfowl areas. Outdoor-layer, turkey (meat and breeder), and duck (meat and breeder) farms had a significantly higher risk for LPAIV introduction than did indoor-layer farms. Except for outdoor-layer, all poultry types (i.e., broilers, chicken breeders, ducks, and turkeys) are kept indoors. For all production types, LPAIV risk decreased significantly with increasing distance to medium-sized waterways and with increasing distance to areas with defined wild waterfowl, but only for outdoor-layer and turkey farms. Future research should focus not only on production types but also on distance to waterways and wild bird areas. In addition, settlement of new poultry farms in high-risk areas should be discouraged.

  7. Drinking and driving among Italian adolescents: Trends over seven years (2007-2013).

    PubMed

    Siciliano, Valeria; Mezzasalma, Lorena; Scalese, Marco; Doveri, Cristina; Molinaro, Sabrina

    2016-03-01

    In recent years, increasing attention has been paid to the issue of driving under the influence of alcohol (DUI), especially among young people. The aims of the present study were (1) to analyse the trends of DUI, riding with a driver under influence of alcohol (RWDUI) and alcohol-related road crashes (A-rC) in a nationally representative sample of students in the period 2007-2013, (2) to assess how different drinking patterns were associated with DUI and RWDUI, (3) to evaluate other influential factors (such as gender, older siblings' and friends' behaviour with alcohol) on DUI and RWDUI. Data were drawn from the cross-sectional European School Survey Project on Alcohol and Other Drugs (ESPAD) carried out annually in Italy. The sample size ranged from 25,555 to 40,390 students (15-19 years old). Results were stratified for students <18 years and ≥18 years old. Although a significant decreasing trend for alcohol consumption was observed only in the younger group, a significant decrease in DUI [APC (annual percent change) -9.7 in the younger and -6.4 in the older group] and in RWDUI (APC -6.7 in the younger and -4.8 in the older group) was detected. A significant decreasing trend of A-rC was observed only in the older group (APC -3.4). Three specific drinking patterns were identified: "Drinking to Excess" (DE), "Drinking with Intoxication" (DI) and "Drinking but Not to Excess" (DNE). In both age groups, the DE pattern significantly increased the likelihood of DUI, whereas the DI pattern was negatively associated, and the DNE pattern was not associated. Different results were found for RWDUI: the DE and DI patterns where significantly associated with RWDUI, whereas the DNE pattern was negatively associated. Overall, illegal substance use, parental monitoring, peers' and siblings' influence were associated with DUI and RWDUI. The change in behaviour towards DUI and RWDUI suggests a cumulative effectiveness of current alcohol policies, although further actions

  8. Explaining the recent decrease in US infant mortality rate, 2007-2013.

    PubMed

    Callaghan, William M; MacDorman, Marian F; Shapiro-Mendoza, Carrie K; Barfield, Wanda D

    2017-01-01

    The US infant mortality rate has been steadily decreasing in recent years as has the preterm birth rate; preterm birth is a major factor associated with death during the first year of life. The degree to which changes in gestational age-specific mortality and changes in the distribution of births by gestational age have contributed to the decrease in the infant mortality rate requires clarification. The objective of the study was to better understand the major contributors to the 2007-2013 infant mortality decline for the total population and for infants born to non-Hispanic black, non-Hispanic white, and Hispanic women. We identified births and infant deaths from 2007 and 2013 Centers for Disease Control and Prevention National Vital Statistics System's period linked birth and infant death files. We included all deaths and births for which there was a reported gestational age at birth on the birth certificate of 22 weeks or greater. The decrease in the infant mortality rate was disaggregated such that all of the change could be attributed to improvements in gestational age-specific infant mortality rates and changes in the distribution of gestational age, by week of gestation, using the Kitagawa method. Sensitivity analyses were performed to account for records in which the obstetric estimate of gestational age was missing and for deaths and births less than 22 weeks' gestation. Maternal race and ethnicity information was obtained from the birth certificate. The infant mortality rates after exclusions were 5.72 and 4.92 per 1000 live births for 2007 and 2013, respectively, with an absolute difference of -0.80 (14% decrease). Infant mortality rates declined by 11% for non-Hispanic whites, by 19% for non-Hispanic blacks, and by 14% for Hispanics during the period. Compared with 2007, the proportion of births in each gestational age category was lower in 2013 with the exception of 39 weeks during which there was an increase in the proportion of births from 30.1% in

  9. Monitoring a Prison Opioid Treatment Program Over a Period of Change to Clinical Governance Arrangements, 2007-2013.

    PubMed

    Larney, Sarah; Lai, Wilson; Dolan, Kate; Zador, Deborah

    2016-11-01

    Opioid substitution therapy (OST) is an effective treatment for opioid dependence that is provided in many correctional settings, including New South Wales (NSW), Australia. In 2011, changes to the clinical governance of the NSW prison OST program were implemented, including a more comprehensive assessment, additional specialist nurses, and centralization of program management and planning. This study aimed to document the NSW prison OST program, and assess the impact of the enhanced clinical governance arrangements on retention in treatment until release, the provision of an OST prescription to patients at release, and presentation to a community OST clinic within 48 hours of release from custody. Data from the NSW prison OST program were obtained for the calendar years 2007-2013. Outcomes were analyzed quarterly using log binomial segmented regression. 8577 people were treated with OST in NSW correctional centers, 2007-2013. Over the entire study period, patients were retained in OST until release in 82% of treatment episodes; a prescription for OST was able to be arranged prior to release in 90% of releases; and patients presented to a community clinic within 48 hours of release in 94% of releases with prescriptions. Following the introduction of the changes to clinical governance, there was a significant increasing trend in retention in OST until release, and in provision of an OST prescription at release. There was an initial increase, followed by a decreasing trend, in presentation to a community clinic within 48 hours of release. This large prison-based OST program has high rates of retention in treatment and continuity of care as patients transition from custody to the community. Strengthened clinical governance arrangements were associated with increased retention in treatment until release and increased provision of an OST prescription at release, but did not improve clinic attendance following release from custody. Copyright © 2016 Elsevier Inc. All

  10. Upwelling characteristics in the Gulf of Finland (Baltic Sea) as revealed by Ferrybox measurements in 2007-2013

    NASA Astrophysics Data System (ADS)

    Kikas, Villu; Lips, Urmas

    2016-07-01

    Ferrybox measurements have been carried out between Tallinn and Helsinki in the Gulf of Finland (Baltic Sea) on a regular basis since 1997. The system measures autonomously water temperature, salinity, chlorophyll a fluorescence and turbidity and takes water samples for further analyses at a predefined time interval. We aimed to show how the Ferrybox technology could be used to study the coastal upwelling events in the Gulf of Finland. Based on the introduced upwelling index and related criteria, 33 coastal upwelling events were identified in May-September 2007-2013. The number of events, as well as the frequency of their occurrence and intensity expressed as a sum of daily average temperature deviations in the 20 km wide coastal area, were almost equal near the northern and southern coasts. Nevertheless, the wind impulse, which was needed to generate upwelling events of similar intensity, differed between the northern and southern coastal areas. It is suggested that the general thermohaline structure adapted to the prevailing forcing and the estuarine character of the basin weaken the upwelling created by the westerly to southwesterly (up-estuary) winds and strengthen the upwelling created by the easterly to northeasterly (down-estuary) winds. Two types of upwelling events were identified - one characterized by a strong temperature front and the other revealing gradual decrease in temperature from the open sea to the coastal area, with maximum temperature deviation close to the shore.

  11. [Dynamics of Purple Sulfur Bacteria in a Meromictic Saline Lake Shunet (Khakassia, Siberia) in 2007-2013].

    PubMed

    Rogozin, D Yu; Zykova, V V; Tarnovskii, M O

    2016-01-01

    According to the results of seasonal monitoring, in 2007-2013 purple sulfur bacteria morphologically similar to Thiocapsa sp. Shira_1 (AJ633676 in EMBL/GenBank) predominated in the anoxygenic phototrophic community of the water column of the meromictic Lake Shira (Khakassia, Siberia). No pronounced seasonal periodicity in the total cell number in the water column was revealed during the period of observation. In some years cell number during the period when the lake was covered with ice was reliably higher than in summer. The absence ofseasonal periodicity was probably due to the low amplitude of seasonal variations in temperature and illumination in the redox zone, resulting from its relatively deep location (12-16 m). The year-to-year dynamics was characterized by a reliable decrease of the total cell number in 2009-2010 and maxima in 2007 and 2011-2012. Canonical correlation analysis revealed that water temperature in the redox zone was the best predictor of the PSB abundance in Lake Shira. Water temperature, in turn, depended on the depth of mixing of the water column. Intense mixing in 2009-2011 was probably responsible for decreased PSB abundance in the lake. On the other hand, the absence of deep winter mixing, resulting in stable conditions in the chemocline, favored the preservation of relatively high PSB biomass. Prediction of circulation depth, which.depends mainly on the weather conditions and dynamics of the water level, is required for prediction of PSB abundance in Lake Shira. These results may be useful for paleolimnological reconstructions of the history of the lake based on the remnants of purple sulfur bacteria in bottom sediments.

  12. Human resources for health in Peru: recent trends (2007-2013) in the labour market for physicians, nurses and midwives.

    PubMed

    Jimenez, M Michelle; Bui, Anthony L; Mantilla, Eduardo; Miranda, J Jaime

    2017-09-21

    Most analyses of gaps in human resources for health (HRH) do not consider training and the transition of graduates into the labour market. This study aims to explore the labour market for Peru's recent medical, nursing, and midwifery graduates as well as their transition into employment in the Ministry of Health's (MOH) system. Data from four different datasets, covering 2007-2013, was used to characterize the patterns of recently trained physicians, nurses, midwives, and postgraduate-trained physicians that enter employment in the MOH system, and scenario analyses were used to describe how this rate of entry needs to adapt in order to fill current HRH shortages. HRH graduates have been increasing from 2007 to 2011, but the proportions that enter employment in the MOH system 2 years later range from 8 to 45% and less than 10% of newly trained medical specialists. Scenario analyses indicate that the gap for physicians and nurses will be met in 2027 and 2024, respectively, while midwives in 2017. However, if the number of HRH graduates entering the MOH system doubles, these gaps could be filled as early as 2020 for physicians and 2019 for nurses. In this latter scenario, the MOH system would still only utilize 56% of newly qualified physicians, 74% of nurses, and 66% of midwives available in the labour market. At 2013 training rates, Peru has the number of physicians, nurses, and midwives it needs to address HRH shortages and meet estimated HRH gaps in the national MOH system during the next decade. However, a significant number of newly qualified health professionals do not work for the MOH system within 2 years of graduation. These analyses highlight the importance of building adequate incentive structures to improve the entry and retention of HRH into the public sector.

  13. Hypervirulent Klebsiella pneumoniae clones causing bacteraemia in adults in a teaching hospital in Barcelona, Spain (2007-2013).

    PubMed

    Cubero, M; Grau, I; Tubau, F; Pallarés, R; Dominguez, M A; Liñares, J; Ardanuy, C

    2016-02-01

    Virulent hypermucoviscous Klebsiella pneumoniae strains associated with the magA and rmpA genes have mainly emerged in Asia. We analysed the frequency and the clinical and molecular epidemiology of K. pneumoniae bacteraemia isolates obtained over a 7-year period (2007-2013). Fifty-three of 878 K. pneumoniae invasive isolates (5.4%) showed a hypermucoviscous phenotype (by the string test). Of these, 16 (30.2%) were magA(+)/rmpA(+), 12 (22.6%) were magA(-)/rmpA(+), and the remaining 25 (47.2%) were magA(-)/rmpA(-). After multilocus sequence typing and wzi sequencing, all magA(+)/rmpA(+) isolates were serotype K1 and sequence type (ST)23. Of the 12 magA(-)/rmpA(+) isolates, nine were K2 (ST380, ST86, ST65, ST25 and ST493), and three magA(-)/rmpA(+) isolates had the new wzi allele 122, an unknown serotype, and the new ST1013. The remaining isolates, which were magA(-)/rmpA(-), showed different serotypes and STs. Patients with magA(+)/rmpA(+) or magA(-)/rmpA(+)K. pneumoniae bacteraemia more frequently had pyogenic liver abscesses (PLAs) and pneumonia than patients with magA(-)/rmpA(-)K. pneumoniae bacteraemia (respectively: 21.4% vs. 8%, p 0.26; and 17.9% vs. 0%, p 0.05). In fact, magA(-)/rmpA(-) isolates were similar to the those termed 'classic' K. pneumoniae isolates causing bacteraemia, the urinary and biliary tracts being the main foci of infection. In conclusion, hypervirulent clones (CC23K1, CC86K2, CC65K2, and CC380K2) were infrequent among K. pneumoniae isolates causing bacteraemia in our geographical area. A hypermucoviscous phenotype as determined with the string test is not enough to recognize these clones; additional molecular studies are needed. Patients with magA(+) and/or rmpA(+)K. pneumoniae bacteraemia more frequently had PLAs and pneumonia than patients without hypermucoviscosity genes. Copyright © 2015. Published by Elsevier Ltd.

  14. Long-term (2007-2013) analysis of aerosol optical properties over four locations in the Indo-Gangetic plains.

    PubMed

    Bibi, Humera; Alam, Khan; Blaschke, Thomas; Bibi, Samina; Iqbal, Muhammad Jawed

    2016-08-10

    The emphasis of the present work lies on the examination of the distribution and spectral behavior of the optical properties of atmospheric aerosols in the Indo-Gangetic plains (IGP). Measurements were performed using an AErosol RObotic NETwork (AERONET) Sun photometer at four sites (Karachi, Lahore, Jaipur, and Kanpur) with different aerosol environments during the period 2007-2013. The aerosol optical depth (AOD) and Ångström exponent (α) were measured, and the results revealed a high AOD with a low α value over Karachi and Jaipur in July, while a high AOD with a high α value was reported over Lahore and Kanpur during October and December. The pattern of the aerosol volume size distribution (VSD) was similar across all four sites, with a prominent peak in coarse mode at a radius of 4.0-5.0 μm, and in fine mode at a radius of 0.1-4.0 μm, for all seasons. On the other hand, during the winter months, the fine-mode peaks were comparable to the coarse mode, which was not the case during the other seasons. The single scattering albedo (SSA) was found to be strongly wavelength-dependent during all seasons and for all sites, with the exception of Kanpur, where the SSA decreases with increasing wavelength during winter and post-monsoon. It was found that the phase function of the atmospheric aerosol was high at a small angle and stable around a scattering angle of 90°-180° at all sites and during all seasons. Spectral variation of the asymmetry parameter (ASY) revealed a decreasing trend with increasing wavelength, and this decreasing trend was more pronounced during the summer, winter, and post-monsoon as compared to pre-monsoon. Furthermore, extensive measurements suggest that both real (RRI) and imaginary (IRI) parts of the refractive index (RI) show contrasting spectral behavior during all seasons. Finally, the analysis of the National Oceanic and Atmospheric Administration hybrid single particle Lagrangian integrated trajectory model back trajectory revealed

  15. Stop, Question, and Complain: Citizen Grievances Against the NYPD and the Opacity of Police Stops Across New York City Precincts, 2007-2013.

    PubMed

    Rengifo, Andres F; Fowler, Kurt

    2016-04-01

    Data on police stops can be examined to reflect on the relative "opacity" of these encounters and how aggregate patterns on the nature-not just the volume-of reported stops relate to public scrutiny of the police. We hypothesize that public scrutiny on police stops is positively related to the prevalence of opaque stop practices across dimensions of "intrusiveness," "rationale," and "setting" derived from agency records. We further argue that this relationship is influenced by neighborhood conditions in the form of concentrated disadvantage, residential instability, and heterogeneity. To develop these ideas, we draw on a publicly available NYPD dataset on police stops to specify a series of fixed and random effects models that describe variation in recorded stop practices across precincts (N = 74) and overtime (T = 7, 2007-2013). We relate these practices to neighborhood conditions derived from the Census and examine their association with rates of SQF complaints to the CCRB. Results show considerable variation in indicators of opacity, particularly across precincts. More importantly, we also find that rates of complaints are higher in precincts that have more vaguely defined, intrusive stops. Results also suggest that concentrated disadvantage is independently and positively related with higher rates of public scrutiny of the police.

  16. Atypical femoral fractures in Italy: a retrospective analysis in a large urban emergency department during a 7-year period (2007-2013).

    PubMed

    Pedrazzoni, Mario; Giusti, Andrea; Girasole, Giuseppe; Abbate, Barbara; Verzicco, Ignazio; Cervellin, Gianfranco

    2016-11-09

    The aim of this study was to determine the incidence of atypical femoral fractures (AFFs) seen in a large emergency department in Italy. It was a retrospective study of all men and women aged 40 years or older admitted to the Emergency Department of Parma University Hospital for a femoral fracture. Cases were identified in the hospital database with use of International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) code 820 or 821 or text strings. All the radiographic images of fractures not clearly identified as proximal or condylar were retrieved and evaluated by three independent reviewers. Fractures were considered as atypical if all three reviewers agreed on at least four of five major features defined by the 2013 American Society for Bone and Mineral Research criteria. In the 7-year period (2007-2013), with a total follow-up of 1,383,154 patient-years, we found 22 AFFs in 21 patients, accounting for 7.1% of low-trauma subtrochanteric/femoral shaft fractures and 0.6% of all femoral fractures. The incidence was very low (1.6 in 100,000 patient-years in both sexes combined). In contrast, the incidence of classic fractures of the proximal end of the femur was at least two orders of magnitude higher (typical/atypical rate ratio 152). Bisphosphonate use was reported in 13 patients (62%; mean treatment duration 9 years; range 5-14 years). Among 286 patients with typical subtrochanteric/femoral shaft fractures, 20 were being treated with bisphosphonate (7%; odds ratio 22; 95% confidence interval 8-58; p < 0.001). This study confirms the very low incidence of AFFs in the largest Italian cohort of patients to date. Even though the risk is higher in patients treated with bisphosphonates, AFFs are very rare, and typical femoral fractures are at least 100-fold more frequent.

  17. Estimating influenza and respiratory syncytial virus-associated mortality in Western Kenya using health and demographic surveillance system data, 2007-2013.

    PubMed

    Emukule, Gideon O; Spreeuwenberg, Peter; Chaves, Sandra S; Mott, Joshua A; Tempia, Stefano; Bigogo, Godfrey; Nyawanda, Bryan; Nyaguara, Amek; Widdowson, Marc-Alain; van der Velden, Koos; Paget, John W

    2017-01-01

    Influenza and respiratory syncytial virus (RSV) associated mortality has not been well-established in tropical Africa. We used the negative binomial regression method and the rate-difference method (i.e. deaths during low and high influenza/RSV activity months), to estimate excess mortality attributable to influenza and RSV using verbal autopsy data collected through a health and demographic surveillance system in Western Kenya, 2007-2013. Excess mortality rates were calculated for a) all-cause mortality, b) respiratory deaths (including pneumonia), c) HIV-related deaths, and d) pulmonary tuberculosis (TB) related deaths. Using the negative binomial regression method, the mean annual all-cause excess mortality rate associated with influenza and RSV was 14.1 (95% confidence interval [CI] 0.0-93.3) and 17.1 (95% CI 0.0-111.5) per 100,000 person-years (PY) respectively; and 10.5 (95% CI 0.0-28.5) and 7.3 (95% CI 0.0-27.3) per 100,000 PY for respiratory deaths, respectively. Highest mortality rates associated with influenza were among ≥50 years, particularly among persons with TB (41.6[95% CI 0.0-122.7]); and with RSV were among <5 years. Using the rate-difference method, the excess mortality rate for influenza and RSV was 44.8 (95% CI 36.8-54.4) and 19.7 (95% CI 14.7-26.5) per 100,000 PY, respectively, for all-cause deaths; and 9.6 (95% CI 6.3-14.7) and 6.6 (95% CI 3.9-11.0) per 100,000 PY, respectively, for respiratory deaths. Our study shows a substantial excess mortality associated with influenza and RSV in Western Kenya, especially among children <5 years and older persons with TB, supporting recommendations for influenza vaccination and efforts to develop RSV vaccines.

  18. Impact of the 2008 global financial crisis on the health of Canadians: repeated cross-sectional analysis of the Canadian Community Health Survey, 2007-2013.

    PubMed

    Nour, Sabrina; Labonté, Ronald; Bancej, Christina

    2017-04-01

    Despite a clear impact on the Canadian economy, little is known about the subsequent health impacts of the 2008 global financial crisis (GFC) in this country. This study fills this gap in knowledge by conducting a repeated cross-sectional analysis of the Canadian Community Health Survey (CCHS). Data from 7 cycles (2007-2013) of the CCHS were combined to form a large data set representative of the Canadian working-age population (15-64 years) residing in 1 of 10 provinces. A logistic regression model was used to determine whether exposure to various periods of the GFC resulted in increased odds of reporting poor mental health. Exposure was categorised into 4 periods based on political and economic indicators, as follows: precrisis period (baseline), initial crisis period, stimulus period and austerity period. Other outcomes investigated included: anxiety disorders (AD), mood disorders (MD), poor physical health and health-related behaviours (heavy alcohol drinking (HAD) and decreased fruit/vegetable consumption (FVC)). A significant increased odds of reporting poor mental health was observed during the austerity period compared with the precrisis period (OR=1.26 (1.16 to 1.32)); findings remain significant when adjusted for sex, marital status and education. Exposure to the austerity period was also significantly associated with increased odds of reporting AD, MD, HAD and decreased odds of FVC. No significant associations were observed for the poor self-perceived physical health variable. Statistically significant associations were observed between several negative health outcomes and the austerity period when compared with the precrisis period. Austerity has been linked to worsening health in other studies and represents an example of how the policy response can have greater detrimental impact on health than the financial crisis itself. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to

  19. Growth in Western Australian emergency department demand during 2007-2013 is due to people with urgent and complex care needs.

    PubMed

    Aboagye-Sarfo, Patrick; Mai, Qun; Sanfilippo, Frank M; Preen, David B; Stewart, Louise M; Fatovich, Daniel M

    2015-06-01

    To determine the magnitude and characteristics of the increase in ED demand in Western Australia (WA) from 2007 to 2013. We conducted a population-based longitudinal study examining trends in ED demand, stratified by area of residence, age group, sex, Australasian Triage Scale category and discharge disposition. The outcome measures were annual number and rate of ED presentations. We calculated average annual growth, and age-specific and age-standardised rates. We assessed the statistical significance of trends, overall and within each category, using the Mann-Kendall trend test and analysis of variance ANOVA. We also calculated the proportions of growth in ED demand that were attributable to changes in population and utilisation rate. From 2007 to 2013, ED presentations increased by an average 4.6% annually from 739,742 to 945,244. The rate increased 1.4% from 354.1 to 382.6 per 1000 WA population (P = 0.02 for the trend). The main increase occurred in metropolitan WA, age 45+ years, triage category 2 and 3 and admitted cohorts. Approximately three-quarters of this increase was due to population change (growth and ageing) and one-quarter due to increase in utilisation. Our study reveals a 4.6% annual increase in ED demand in WA in 2007-2013, mostly because of an increase in people with urgent and complex care needs, and not a shift (demand transfer) from primary care. This indicates that a system-wide integrated approach is required for demand management. © 2015 Australasian College for Emergency Medicine and Australasian Society for Emergency Medicine.

  20. [Mode of delivery among HIV-positive pregnant women in areas with high prevalence of HIV in China, 2007-2013].

    PubMed

    Wang, Q; Wang, L H; Wang, A L; Wang, F; Wang, X Y; Qiao, Y P; Su, M; Dou, L X; Fang, L W

    2016-07-06

    To describe the changing demographic profile over time of pregnant women diagnosed with HIV infection, and trends in mode of delivery and pregnancy outcome. An observational investigation was conducted based on a population of 1 128 HIV-positive pregnant women at eight sites in China in provinces with high prevalence of HIV among pregnant women and children between 2007 and 2013. The study area included Shangcai and Weishi counties in Henan province; Ruili and Longchuan counties and Linxiang prefecture in Yunnan province; Yining County in Xinjiang; and Lingshan county and Babu district in Guangxi province. Main outcome measures were maternal characteristics, mode of delivery, and related trends over time by Cochram-Mantel-Haenszel(CMH) χ(2)-test. A total hospital delivery rate of 96.4% was reported. For each year during the period 2007-2013, hospital delivery rates were 95.1% (253/266), 94.8% (188/198), 93.7% (164/175), 98.8% (159/161), 98.6% (141/143), 97.4% (114/117), and 100.0% (68/68), respectively (χ(2)CMH=7.68, P=0.006). The neonatal survival rate increased by 0.7% incrementally from 2007 to 2013, with 98.5% (262/266), 99.0% (196/198), 99.4% (174/175), 99.4% (160/161), 100.0% (143/143), 100.0% (117/117), and 100.0% (68/68), respectively (χ(2)CMH=4.58, P=0.030). The proportions of vaginal deliveries in those years were 62.2% (166/266), 54.8% (109/198), 59.9% (105/175), 61.7% (100/161), 66.7% (96/143), 58.8% (69/117), and 66.7% (46/68), respectively (χ(2)CMH=1.19, P= 0.276). The average rate for midwives skilled in procedures such as artificial rupture of membranes and episiotomy was 37.8% (261/691), with proportions decreasing during the study period at 39.2% (65/166), 47.4% (52/109), 35.9% (38/105), 46.0% (46/100), 25.5% (25/96), 31.2% (22/69), and 28.3% (13/46), respectively (χ(2CMH)=6.76, P=0.009). The annual rate of reported hospital delivery increased between 2007 and 2013, with a declining rate of skilled midwifery over the same period. Survival of

  1. Long-term 2007-2013 monitoring of reproductive disturbance in the dun sentinel Assiminea grayana with regard to polymeric materials pollution at the coast of Lower Saxony, North Sea, Germany.

    PubMed

    Watermann, B T; Löder, M; Herlyn, M; Daehne, B; Thomsen, A; Gall, K

    2017-02-01

    During biological effect monitoring studies of endocrine active compounds with the snail Assiminea grayana in 2007-2013, reproductive disorders including atresia, transformation of capsule/albumen glands into prostates in females and ovotestis, transformation of prostates to capsule/albumen glands, disruption of spermatogenesis, and calcification of tubules in males, were encountered in several years. The search of sources of endocrine active substances was first directed to antifouling biocides from paint particles and extended to leaching compounds from polymeric materials. In contrast to the reference sites, most of the observed disorders occurred at a station near harbors and dockyards polluted with residues from antifouling paints and polymeric materials. Beside of investigations about the potential ingestion of polymer particles by the snails, further investigations of compounds of polymeric materials with endocrine potential should follow.

  2. Geoscience outreach in Africa, 2007-2013

    NASA Astrophysics Data System (ADS)

    De Mulder, Eduardo F. J.; Eder, Wolfgang; Mogessie, Aberra; Ahmed, Enas A. E.; Da Costa, Pauline Y. D.; Yabi, Ibouraïma; Mathu, Eliud; Muhongo, Sospeter; Cloetingh, Sierd A. P. L.

    2014-11-01

    Geoscience outreach is an important communication tool for geoscientists to approach politicians, decision makers, and the general public. This tool is used to inform them about the added values of the geosciences for the national economy and to cope with environmental challenges. Moreover, geoscience outreach aims to excite (in particular young) people to be interested in the Earth sciences. There is a growing gap between demand for and supply of geo-experts. Main target of the International Year of Planet Earth (IYPE 2007-2009) was to help close this gap by informing students to follow a professional career in the geosciences. The successful IYPE outreach programme was predominantly implemented at a grass root level through the 80 national and regional IYPE Committees, 14 of which in Africa. Reports are given on the geoscience outreach activities conducted under the IYPE, in these African nations during the period 2007-2009. Upon closure of the IYPE, the Earth Science Matters Foundation was established to continue implementing the outreach objectives of the IYPE. Reports from five African nations show that geoscience outreach activities have continued after 2009. Main challenges reported are lack of funding, lack of priority, and lack of qualified personnel. Finally, some possible recommendations to cope with such challenges are suggested.

  3. Factors associated with anemia in children under three years of age in Perú: analysis of the Encuesta Demográfica y de Salud Familiar, ENDES, 2007-2013.

    PubMed

    Velásquez-Hurtado, José Enrique; Rodríguez, Yuleika; Gonzáles, Marco; Astete-Robilliard, Laura; Loyola-Romaní, Jessica; Vigo, Walter Eduardo; Rosas-Aguirre, Ángel Martín

    2016-06-03

    Despite the reduction of poverty in Perú, the prevalence of anemia in the country remains high.  To identify socio-demographic, child and maternal-child care factors associated with anemia in children between 6 and 35 months in Perú.  We conducted an analytical and descriptive study that included registered data from the national survey on demography and family health, 2007-2013, on children between 6 and 35 months old, including the measurement of blood hemoglobin. Anemia was confirmed by hemoglobin-altitude corrected values below 11 mg/dl. We used multivariate logistic regression models to assess potential associated factors for anemia.  Anemia prevalence was high (47.9%). Twelve factors were independently associated with anemia in children: Socio-demographic factors such as living outside Lima and Callao, in a low socioeconomic household, and having an adolescent mother with low education level; child-related factors as being male, younger than 24 months of age, and having fever in the previous two weeks, and maternal-child care factors such as lack of prenatal control in the first trimester of pregnancy, lack or short period of iron supplementation during pregnancy, house delivery, anemia detection at the moment of the survey, and lack of intestinal anti-parasite preventive treatment in the child.  The analysis of survey data provided valuable information about factors associated with anemia in children between 6 and 35 months, which can be used to increase the coverage and effectiveness of maternal-child care practices.

  4. Implementation and Operational Research: CD4 Count Monitoring Frequency and Risk of CD4 Count Dropping Below 200 Cells Per Cubic Millimeter Among Stable HIV-Infected Patients in New York City, 2007-2013.

    PubMed

    Myers, Julie E; Xia, Qiang; Torian, Lucia V; Irvine, Mary; Harriman, Graham; Sepkowitz, Kent A; Shepard, Colin W

    2016-03-01

    The evidence has begun to mount for diminishing the frequency of CD4 count testing. To determine whether these observations were applicable to an urban US population, we used New York City (NYC) surveillance data to explore CD4 testing among stable patients in NYC, 2007-2013. We constructed a population-based retrospective open cohort analysis of NYC HIV surveillance data. HIV+ patients aged ≥ 13 years with stable viral suppression (≥ 1 viral load the previous year; all <400 copies per milliliter) and immune status (≥ 1 CD4 the previous year; all ≥ 200 cells per cubic millimeter) entered the cohort the following year beginning January 1, 2007. Each subsequent year, eligible patients not previously included entered the cohort on January 1. Outcomes were annual frequency of CD4 monitoring and probability of maintaining CD4 ≥ 200 cells per cubic millimeter. A multivariable Cox model identified factors associated with maintaining CD4 ≥ 200 cells per cubic millimeter. During 1.9 years of observation (median), 62,039 patients entered the cohort. The mean annual number of CD4 measurements among stable patients was 2.8 and varied little by year or characteristic. Two years after entering, 93.4% and 97.8% of those with initial CD4 350-499 and CD4 ≥ 500 cells per cubic millimeter, respectively, maintained CD4 ≥ 200 cells per cubic millimeter. Compared to those with initial CD4 ≥ 500 cells per cubic millimeter, those with CD4 200-349 cells per cubic millimeter and CD4 350-499 cells per cubic millimeter were more likely to have a CD4 <200 cells per cubic millimeter, controlling for sex, race, age, HIV risk group, and diagnosis year. In a population-based US cohort with well-controlled HIV, the probability of maintaining CD4 ≥ 200 cells per cubic millimeter for ≥ 2 years was >90% among those with initial CD4 ≥ 350 cells per cubic millimeter, suggesting that limited CD4 monitoring in these patients is appropriate.

  5. Volcanic Eruptions in the southern Red Sea 2007-2013

    NASA Astrophysics Data System (ADS)

    Jónsson, Sigurjón; Xu, Wenbin; Ruch, Joël

    2017-04-01

    After more than a century of volcanic quiescence the southern Red Sea has seen three volcanic eruptions during the past decade. The eruptions occurred on Jebel at Tair Island in 2007-8 and within the Zubair archipelago in 2011-12 and 2013. As the islands are remote, without geophysical instrumentation, and lack direct observers, we obtained most of the information about these eruptions from studying Synthetic Aperture Radar (SAR) and optical satellite images. We used the images to deduce the timing and progress of the volcanic activity and to constrain the geometry of the dikes feeding the eruptions. The Jebel at Tair eruption started energetically and caused damage to Yemeni military buildings on the island and even a few casualties. The erupted lava came from a short summit fissure and covers about 6 km2, which is almost half of the island. The fissure orientations of this and previous eruptions indicate that the stress field on Tair Island is temporarily varying and isolated from the regional Red Sea stress field. The eruptions within the Zubair archipelago, which is located about 50 km southeast of Tair Island, produced two new islands and were fed by dikes much larger than the small size of the new islands might suggest. This is indicated by relative displacements between different islands in the archipelago, derived from offset tracking of SAR images. Together the three volcanic eruptions and several seismic swarms indicate that the southern Red Sea has been experiencing a rifting episode with multiple dike intrusions and meter-scale extension, and that this part of the plate boundary is more active than previously thought.

  6. VISCERAL LEISHMANIASIS IN PETROLINA, STATE OFPERNAMBUCO, BRAZIL, 2007-2013.

    PubMed

    Araujo, Andreina de Carvalho; Gonçalves, Nara Nagle Vieira Matos; Dantas-Torres, Filipe; Ferreira, Fernando; Horta, Mauricio Claudio

    2016-01-01

    Visceral leishmaniasis is a life-threatening disease of great public health relevance in Brazil. The municipality of Petrolina is an endemic area in the State of Pernambuco, Brazil. This study was designed to assess the recent expansion of VL in the municipality of Petrolina, Pernambuco. Patients data were obtained from the Brazilian National Information System for Notifiable Diseases (SINAN). A total of 111 records from 2007 to 2013 were investigated, of which 69 were residents in Petrolina. The disease has predominantly affected 1-4 year old children (34.8%). Most of the patients were males (59.4%). Co-infection with human immunodeficiency virus occurred in 14.5% of the cases. The criterion most frequently used was the clinical and epidemiological confirmation (59.4%), with clinical cure in 78.3% of cases and one fatal outcome. Visceral leishmaniasis is endemic in Petrolina with transmission levels varying from moderate to high. The present study has shown the precariousness of the use of diagnostic tests in primary healthcare units, and this misuse has interfered with the diagnosis and treatment of cases.

  7. Research on English Language Teaching and Learning in Argentina (2007-2013)

    ERIC Educational Resources Information Center

    Porto, Melina; Montemayor-Borsinger, Ann; López-Barrios, Mario

    2016-01-01

    In this article we review research on English as a foreign language (EFL) teaching and learning published in Argentina between 2007 and 2013. This is the first review of a Latin American country in this series. Argentina has a century-long tradition of training EFL teachers but a comparatively shorter though fruitful history of foreign language…

  8. Breast cancer in women in their thirties (2007-2013): a retrospective review.

    PubMed

    Arleo, Elizabeth Kagan; Reichman, Melissa; Dashevsky, Brittany Zadek; Babagbemi, Kemi; Drotman, Michele

    2015-01-01

    Due to an increasing number of breast cancer diagnoses in younger women anecdotally noted at our institution, we conceived of this study %was to retrospectively review the records of women diagnosed with breast cancer under the age of 40 for potentially alterable versus unalterable risk factors in their history. Between 2007 and 2013, there were 52 patients less than 40 years of age with breast cancer at our institution: 79% (41/52) presented with a clinical abnormality (palpable mass, nipple discharge or inversion) and 21% (11/52) were asymptomatic but diagnosed on early screening mammograms. Seventy-five percent (39/52) of the cancers had an invasive component and 87% (45/52) were intermediate to high grade. Sixty percent (31/52) of subjects had stage 0 or I disease, but 40% (21/52) had later stage disease (stage II or greater). The vast majority of the cancers were ER+ (82%) and PR+ (78%). Fifty-six percent (28/50; 2 unknown) of the subjects had a documented history of hormonal contraception. Fifty-three percent (27/51; 1 unknown) of had no family history of breast cancer whatsoever, and 80% (41/51) had no family history of breast cancer in a first degree relative. Six were positive for BRCA 1, 2, or a variant (6/52 = 12%).

  9. Nanoplankton and picoplankton in the Western English Channel: abundance and seasonality from 2007-2013

    NASA Astrophysics Data System (ADS)

    Tarran, Glen A.; Bruun, John T.

    2015-09-01

    The nano- and picoplankton community at Station L4 in the Western English Channel was studied between 2007 and 2013 by flow cytometry to quantify abundance and investigate seasonal cycles within these communities. Nanoplankton included both photosynthetic and heterotrophic eukaryotic single-celled organisms while the picoplankton included picoeukaryote phytoplankton, Synechococcus sp. cyanobacteria and heterotrophic bacteria. A Box-Jenkins Transfer Function climatology analysis of surface data revealed that Synechococcus sp., cryptophytes, and heterotrophic flagellates had bimodal annual cycles. Nanoeukaryotes and both high and low nucleic acid-containing bacteria (HNA and LNA, respectively) groups exhibited unimodal annual cycles. Phaeocystis sp., whilst having clearly defined abundance maxima in spring was not detectable the rest of the year. Coccolithophores exhibited a weak seasonal cycle, with abundance peaks in spring and autumn. Picoeukaryotes did not exhibit a discernable seasonal cycle at the surface. Timings of maximum group abundance varied through the year. Phaeocystis sp. and heterotrophic flagellates peaked in April/May. Nanoeukaryotes and HNA bacteria peaked in June/July and had relatively high abundance throughout the summer. Synechococcus sp., cryptophytes and LNA bacteria all peaked from mid to late September. The transfer function model techniques used represent a useful means of identifying repeating annual cycles in time series data with the added ability to detect trends and harmonic terms at different time scales from months to decades.

  10. Prevalence of sexual violence against children and use of social services - seven countries, 2007-2013.

    PubMed

    Sumner, Steven A; Mercy, Ames A; Saul, Janet; Motsa-Nzuza, Nozipho; Kwesigabo, Gideon; Buluma, Robert; Marcelin, Louis H; Lina, Hang; Shawa, Mary; Moloney-Kitts, Michele; Kilbane, Theresa; Sommarin, Clara; Ligiero, Daniela P; Brookmeyer, Kathryn; Chiang, Laura; Lea, Veronica; Lee, Juliette; Kress, Howard; Hillis, Susan D

    2015-06-05

    Sexual violence against children erodes the strong foundation that children require for leading healthy and productive lives. Globally, studies show that exposure to violence during childhood can increase vulnerability to a broad range of mental and physical health problems, ranging from depression and unwanted pregnancy to cardiovascular disease, diabetes, and sexually transmitted diseases, including human immunodeficiency virus (HIV). Despite this, in many countries, the extent of sexual violence against children is unknown; estimates are needed to stimulate prevention and response efforts and to monitor progress. Consequently, CDC, as a member of the global public-private partnership known as Together for Girls, collaborated with Cambodia, Haiti, Kenya, Malawi, Swaziland, Tanzania, and Zimbabwe to conduct national household surveys of children and youth aged 13-24 years to measure the extent of violence against children. The lifetime prevalence of experiencing any form of sexual violence in childhood ranged from 4.4% among females in Cambodia to 37.6% among females in Swaziland, with prevalence in most countries greater than 25.0%. In most countries surveyed, the proportion of victims that received services, including health and child protective services, was ≤10.0%. Both prevention and response strategies for sexual violence are needed.

  11. Consumption of alcoholic beverages, driving vehicles, a balance of dry law, Brazil 2007-2013

    PubMed Central

    Malta, Deborah Carvalho; Berna, Regina Tomie Ivata; da Silva, Marta Maria Alves; Claro, Rafael Moreira; da Silva, Jarbas Barbosa; dos Reis, Ademar Arthur Chioro

    2014-01-01

    The study analyzes the trend in frequency of adults who drive under the influence of alcohol in major Brazilian cities after the passing of laws, which prohibit drunk driving. Data from the Surveillance System for Risk and Protective Factors for Chronic Diseases by Telephone Survey (VIGITEL) between 2007 and 2013 were analyzed. The frequency of adults who drove after abusive alcohol consumption was reduced by 45.0% during this period (2.0% in 2007 to 1.1% in 2013). Between 2007 and 2008 (-0.5%) and between 2012 and 2013 (-0.5%), significant reductions were observed in the years immediately after the publication of these laws that prohibit drunk driving. These improvements towards the control of drunk driving show a change in the Brazilian population’s lifestyle. PMID:25210828

  12. VISCERAL LEISHMANIASIS IN PETROLINA, STATE OF PERNAMBUCO, BRAZIL, 2007-2013

    PubMed Central

    ARAUJO, Andreina de Carvalho; GONÇALVES, Nara Nagle Vieira Matos; DANTAS-TORRES, Filipe; FERREIRA, Fernando; HORTA, Mauricio Claudio

    2016-01-01

    Visceral leishmaniasis is a life-threatening disease of great public health relevance in Brazil. The municipality of Petrolina is an endemic area in the State of Pernambuco, Brazil. This study was designed to assess the recent expansion of VL in the municipality of Petrolina, Pernambuco. Patients data were obtained from the Brazilian National Information System for Notifiable Diseases (SINAN). A total of 111 records from 2007 to 2013 were investigated, of which 69 were residents in Petrolina. The disease has predominantly affected 1-4 year old children (34.8%). Most of the patients were males (59.4%). Co-infection with human immunodeficiency virus occurred in 14.5% of the cases. The criterion most frequently used was the clinical and epidemiological confirmation (59.4%), with clinical cure in 78.3% of cases and one fatal outcome. Visceral leishmaniasis is endemic in Petrolina with transmission levels varying from moderate to high. The present study has shown the precariousness of the use of diagnostic tests in primary healthcare units, and this misuse has interfered with the diagnosis and treatment of cases. PMID:27074323

  13. Adverse events associated with chloramphenicol use in dogs: a retrospective study (2007-2013).

    PubMed

    Short, J; Zabel, S; Cook, C; Schmeitzel, L

    2014-11-29

    Chloramphenicol is a broad spectrum antibiotic that has been increasingly utilised since the emergence of methicillin-resistant staphylococcal infections. Due to toxicities in humans, use of the drug has been limited. In dogs, gastrointestinal signs are common adverse events described, and bone marrow suppression is possible. The aim of this study was to evaluate the adverse events associated with chloramphenicol in dogs seen by one specialty practice from January 2007 through June 2013. The database was searched for all dogs prescribed chloramphenicol during the time period. Dosage, length of treatment, age and body weight of the dogs were recorded as well as any adverse events that occurred during treatment. A total of 105 cases were evaluated. Thirty-nine dogs experienced at least one adverse event while on the medication. The most commonly noted were gastrointestinal signs and hindlimb weakness. The mean body weight for dogs with hindlimb weakness was 35.3 kg, which was significant. Resolution was documented in 54 per cent of cases when the drug was discontinued. Methicillin-resistant Staphylococcus pseudintermedius on bacterial culture was listed as the reason for chloramphenicol use in 76 per cent of the cases. Based on this information, further prospective studies are recommended to evaluate the reproducibility of this report.

  14. Greenland Ice Sheet Surface Elevation at Summit, Greenland: 2007-2013

    NASA Astrophysics Data System (ADS)

    Lutz, E.; Hawley, R. L.; Herring, T.

    2013-12-01

    Quantifying surface elevation change is essential for ice sheet mass balance estimates. We assessed surface elevation and elevation change of the Greenland Ice Sheet at a range of spatial scales using six years of monthly GPS surveys conducted near Summit between 8/2007 and 3/2013. The ~11 km route consists of 15 transects that run parallel and orthogonal to IceSat's groundtrack 412 and includes 121 repeat locations spatially distributed along the route (Figure 1). Horizontal velocities and velocity gradients derived from base station and transect positions agree closely with previous studies. At the survey scale, no significant linear elevation trend is evident over the study period. However, local- and transect-scale time series revealed significant elevation increases of 1--2 cm per year in the central and southern regions of the survey that spatially and temporally may correlate with wind transport events from Summit station. This finding illustrates how sample scale (e.g., density, location and extent) affects surface elevation estimates critical to remote sensing validation and mass balance estimation. Spectral time series analysis showed that the expected annual elevation cycle was dwarfed by a two-year periodicity that dominated nearly all time series. The elevation maximum of Winter 2012-2013 fell short of the expected elevation peak, possibly due to accelerated compaction forced by high temperatures in the preceding Summer of 2012. We also highlight spatial comparisons with elevation products from three NASA altimeters, including the Airborne Topographic Mapper (ATM), the Land, Vegetation, and Ice Sensor (LVIS), and the Multiple Altimeter Beam Experiment Lidar (MABEL). This unique long-term GPS dataset is valuable for assessing ice sheet elevation change at a range of spatial-temporal scales, and for validating remote sensing products. With continued effort this survey will provide invaluable ground-based observations linking ICESat, IceBridge and ICESat-2 data products at Summit, Greenland.

  15. Counterinsurgency in Somalia: Lessons Learned from the African Union Mission in Somalia, 2007-2013

    DTIC Science & Technology

    2014-09-01

    government. Though the TFG was widely regarded in Somalia as a Western proxy, the Obama administration was careful to provide only limited and indirect... Barack Obama’s first term in office. Within both administrations and among Somali experts, however, there was a persistent division of opinion about...when (pull).242 U.S. direct action on non-Somali HVTs helped to put pressure on al- Shabaab. Some U.S. direct action on HVTs under the Obama

  16. Clostridium difficile Infection in the Department of Defense (DOD): 2007-2013

    DTIC Science & Technology

    2015-02-01

    Edwards JR, Cohen J, et al. Effect of nucleic acid amplification testing on population-based incidence rates of Clostridium difficile infection. Clin...Comorbidity Burden among CDI Patients............................................................. 14 Previous Antibiotic and Gastric Acid Inhibitor...23 Previous Antibiotic and Gastric Acid Inhibitor Use

  17. Adverse drug reactions in Colombian patients, 2007-2013: Analysis of population databases.

    PubMed

    Machado-Alba, Jorge Enrique; Londoño-Builes, Manuel José; Echeverri-Cataño, Luis Felipe; Ochoa-Orozco, Sergio Andrés

    2016-03-03

    Recognizing adverse drug reactions (ADRs) is becoming more important in clinical practice.  To determine the frequency of adverse drug reactions and ADR suspicions among the population affiliated to the Colombian health system and to describe the drugs, reactions and associated variables.  We revised ADRs and ADRs suspicion databases from drugs dispensed by Audifarma, S.A., both for inpatient and outpatient care from 2007 to 2013. Variables included ADR report date, city, drug, drug's Anatomical Therapeutic Classification (ATC), ADR severity, ADR type, ADR classification and ADR probability according to the World Health Organization's definitions.  We obtained 5,342 reports for 468 different drugs. The ATC groups with the most reports were anti-infectives for systemic use (25.5%), nervous system agents (17.1%) and cardiovascular system drugs (15.0%). The drugs with the highest number of reports were metamizole (4.2%), enalapril (3.8%), clarithromycin (2.8%), warfarin (2.5%) and ciprofloxacin (2.4%). The most common ADR, classified following the World Health Organization adverse reaction terminology, were: skin and appendages disorders (35.3%), general disorders (14.2%) and gastrointestinal system disorders (11.8%). Overall, 49.4% of the ADRs were classified as "moderate" and 45.1% as "mild".  An increasing number of ADR reports were found coinciding with a worldwide tendency. Differences between inpatient and outpatient ADR reports were found when compared to scientific publications. The information on ADR reports, mainly gathered by the Instituto Nacional de Vigilancia de Medicamentos y Alimentos - Invima, should be made public for academic and institutional use.

  18. Changes in Policy Maker Attitudes Toward Active Living Communities Issues in Hawaii, 2007-2013.

    PubMed

    McGurk, Meghan; Maddock, Jay

    2016-10-01

    Obesity and lack of physical activity are major public health problems in the United States. Well-designed, active living communities (ALCs) can help support physically active lifestyles. This study assessed attitudes of Hawaii decision makers in 2007 and 2013 to determine if priorities toward ALCs changed. Elected and appointed state and county officials were mailed surveys both years. Respondents rated the importance of 23 specified problems, which included 1 obesity variable and 5 ALC variables. The survey was completed by 126 (70.4%) respondents in 2007 and 117 (60.9%) in 2013. Among the specific problems, only obesity increased in rank from 14th to ninth place. Three variables fell more than 2 places: increasing traffic (fifth to seventh place), poorly planned development and sprawl (seventh to 11th place) and pedestrian safety (12th to 17th place). The other 2 stayed relatively the same: lack of pedestrian walkways, sidewalks, and crosswalks (16th to 15th place) and lack of recreational activities (22nd to 23rd place). Across years, obesity concerns have increased but do not appear to be tied to increases in concern for ALC variables. More education for policymakers on the link between obesity, physical activity, and the built environment is necessary.

  19. Clinical and epidemiological aspects of complicated malaria in Colombia, 2007-2013.

    PubMed

    Chaparro-Narváez, Pablo E; Lopez-Perez, Mary; Rengifo, Lina Marcela; Padilla, Julio; Herrera, Sócrates; Arévalo-Herrera, Myriam

    2016-05-10

    During the last decade, Colombia presented a significant decrease in malaria clinical cases and associated mortality. However, there is a lack of reliable information about the prevalence and characteristics of complicated malaria cases as well as its association with different Plasmodium species. A description of the epidemiological and clinical aspects of complicated malaria in Colombia is presented here. A descriptive study was conducted using data collected between 2007 and 2013 by the Public Health Surveillance System (SIVIGILA). Demographic and clinical features were described. Frequency of complicated malaria cases, annual parasite index (API) and annual percent change (APC) for trend modelling by gender and age were also calculated. A total of 547,542 malaria cases were recorded by SIVIGILA during the study period, of which 2553 (0.47 %) corresponded to complicated cases with similar distribution by Plasmodium vivax and Plasmodium falciparum species. Mixed infections were found in 153 cases (6.0 %). Trend modelling of the API for complicated malaria for all parasite species showed a non-significant increase throughout the years (APC 14.4 %; 95 % CI -4.3 to 36.6 %). Complicated malaria individuals were mostly males (62.2 %) and young adults (median age of 23 years). Notably, 72.4 % of the patients attended for malaria diagnosis >72 h after symptoms onset and 17 % reported malaria episodes in the last 30 days. All patients received anti-malarial treatment, but only 40 % received the first-line as recommended by the Colombian guidelines. Overall, hepatic and renal complications were the most common severe manifestations (63.6 %). Whereas hepatic and pulmonary complications were more common in P. vivax infections, renal and cerebral complications were significantly more frequent in patients with P. falciparum. In contrast with mono-infected patients, severe anaemia and shock were more frequent in patients with mixed infection. In contrast with the malaria-decreasing trend over the last years, the complicated malaria trend showed a non-significant annual increase. Therefore, in addition to existing national policies on early diagnosis and prompt anti-malarial treatment, more efforts have to be committed addressing the delayed diagnosis and inadequate treatment found in this study. Improving malaria notification forms, medical assistance skills, and capacity should be prioritized.

  20. Increase in Primary and Secondary Syphilis Notifications in Men in Tokyo, 2007-2013.

    PubMed

    Sugishita, Yoshiyuki; Yamagishi, Takuya; Arima, Yuzo; Hori, Narumi; Seki, Naomi

    2016-01-01

    The number of notified syphilis cases in Tokyo has more than doubled in recent years. The number of reported primary and secondary syphilis cases increased from 108 cases (0.8 per 100,000 population) in 2007 to 245 cases in 2013 (1.9 per 100,000 population). During this period, the majority of cases was male (905/1,024), and the recent increase among primary and secondary syphilis cases was attributed to the increase among males (90/108 [83%] cases in 2007 to 218/245 [89%] cases in 2013); men aged 20-49 years contributed most to the increase, with those aged 30-34 years having the highest notification rate in 2013. Male-to-male transmission was the primary route of infection reported, and men who have sex with men (MSM) accounted for nearly 80% of male cases in 2013. Syphilis appears to be reemerging in Tokyo, and reducing the risk of acquiring syphilis among MSM aged 20-49 years should be a public health priority in Tokyo.

  1. Overview of the Programme TEMPUS IV, 2007-2013: Information for Future Applicants and Beneficiaries

    ERIC Educational Resources Information Center

    European Union, 2010

    2010-01-01

    TEMPUS is a European Union funded Programme which supports the modernisation of higher education in the Partner Countries in Eastern Europe, Central Asia, the Western Balkans and the Mediterranean region, mainly through university cooperation projects. It also aims to promote the voluntary convergence of the higher education systems in the Partner…

  2. [Work-related motor vehicle injuries among workers at a banking institution (2007-2013)].

    PubMed

    Reinoso-Barbero, Luis; Díaz-Garrido, Ramón; González-Gómez, María Fernanda; Fernández-Fernández, Miguel; Capapé-Aguilar, Ana; Garrido-Astray, María Concepción

    2015-01-01

    To study physical harm caused by road accidents (LATT in Spanish) among employees of a Spanish financial institution from 2007 to 2013. Additionally, we tried to define damage features in each sex and at different ages in hurt patients, as well as work disability caused by this type of injury. Cross-sectional study of labor injuries verified by the occupational medical service of the bank. Absolute (n) and relative (%) frequencies related to interesting variables were described. Chi-square test was used to assess correlation. Along the mentioned period of time, 1.517 traumatic occupational injuries were recorded on a population of 14.541 workers. 27% of them were LATT. 1,3% of these were fatal or seriously harmful, significantly associated to sex and age (p < 0,05). Co-driver damage, LATT in itinere and twist or sprain were more common in women. LATT at work and closed fractures were more frequent in men.Work disability caused by LATT was higher than other traumatic occupational injuries. LATT in the studied sample were almost three times higher than LATT are among general Spanish population, but serious lesions in our group were less common.We observed differences in LATT distribution by sexes and ages in workers included in this study, and also a higher incidence of work disability compared to the whole traumatic occupational injuries. Public health and occupational health authorities must find efficient strategies in order to diminish the incidence of these LATT-associated injuries. Copyright belongs to the Societat Catalana de Salut Laboral.

  3. Detection and genotyping of enteroviruses in cerebrospinal fluid in patients in Victoria, Australia, 2007-2013.

    PubMed

    Papadakis, Georgina; Chibo, Doris; Druce, Julian; Catton, Michael; Birch, Chris

    2014-09-01

    Genotyping by VP1 fragment polymerase chain reaction (PCR) and nucleic acid sequencing to detect enterovirus (EV) genotypes was performed directly on 729 EV PCR positive cerebrospinal fluid (CSF) samples collected between 2007 and 2012 from Victorian hospital inpatients. The overall genotype identification rate from CSF-positive material was 43%. The four most common genotypes identified were Echovirus 6 (24%), Echovirus 30 (17%), Echovirus 25 (10%), and Coxsackievirus A9 (10%), together comprising 61% of all EVs typed. The seasonal distribution of all EVs identified followed the recognized pattern of mainly summer epidemics. Three of the four predominant genotypes were present in each of the 6 years in which the study was conducted, with 20 other EV genotypes also detected, often in only a single year. Genotyping of EVs directly in CSF is faster, simpler and more sensitive than traditional virus neutralization assays performed on EV positive samples.

  4. Geographical analysis of socioeconomic factors in risk of domestic burn injury in London 2007-2013.

    PubMed

    Heng, Jacob S; Atkins, Joanne; Clancy, Olivia; Takata, Masao; Dunn, Ken W; Jones, Isabel; Vizcaychipi, Marcela P

    2015-05-01

    This study aims to explore the geographical distribution of burn injuries in Greater London and the association of socioeconomic factors in areas at risk. Data on burn injury cases classified as occurring in patients' own homes in Greater London and admitted to a specialised burns service for ≥1 day during a 7-year period were obtained from the International Burn Injury Database (iBID). Age- and gender-adjusted standardised incidence ratios (SIRs) were calculated for each Lower Layer Super Output Area (LSOA) in Greater London. Bayesian methods were used to calculate relative risks as best estimates of spatially-smoothed SIRs. Of a total of 2911 admissions to specialised burns services in Greater London in the study period, 2100 (72.1%) cases occurred in patients' own homes. Percentage of ethnic minorities (p=0.005), Income Deprivation Affecting Children Index (p<0.001), Health Deprivation and Disability Score (p=0.031), percentage of families with 3 or more children (p=0.004) and Barriers to Housing and Services Score (p=0.001) remained independently associated with the relative risk of paediatric domestic burn injury in a multivariate linear regression model. Percentage of ethnic minorities (p<0.001), Health Deprivation and Disability Score (p<0.001) and Barriers to Housing and Services Score (p=0.036) remained independently associated with the relative risk of adult domestic burn injury in a multivariate linear regression model. Socioeconomic factors are associated with an increased risk of burn injury in Greater London, but may be more important in children than adults. The specific factors identified are ethnicity, poor general health, household structure, housing issues and income deprivation affecting children. Copyright © 2014 Elsevier Ltd and ISBI. All rights reserved.

  5. Analysis of registered cancer clinical trials in Latin America and the Caribbean, 2007-2013.

    PubMed

    Lee, Bridget; Cuervo, Luis G; Rodríguez-Feria, Pablo; Luciani, Silvana

    2016-02-01

    Objective To characterize cancer clinical trials in Latin America and the Caribbean (LAC), with a focus on registration and enrollment trends. Methods Data were collected from 1 285 active cancer clinical trials registered up until 31 May 2014 in the World Health Organization's International Clinical Trial Registry Platform (ICTRP). The trials were categorized by six characteristics of the continuum of cancer control and care: 1) control and planning, 2) prevention, 3) detection and screening, 4) diagnosis, 5) treatment, and 6) survivorship and palliative care. The search strategy protocol included the use of optimized keywords combined with the names of the 43 countries selected for a descriptive analysis. Results A total of 973 registered and 972 enrolled cancer clinical trials between January 2007 and December 2013 were identified. Trends of growth were observed for both registration and enrollment of cancer treatment clinical trials; for other types of cancer clinical trials, trends for registration and enrollment varied in direction. Conclusions Growth trends in the registration of cancer treatment clinical trials indicate incremental adherence to cancer research reporting and improvements in cancer research transparency. The higher proportion of cancer treatment trials versus other types of cancer clinical trials indicates an imbalance in cancer research in the LAC region and suggests the need for more funding and incentives for other areas of research in order to achieve a more comprehensive approach to gaining knowledge on cancer issues.

  6. Overview of the Programme TEMPUS IV, 2007-2013: Information for Future Applicants and Beneficiaries

    ERIC Educational Resources Information Center

    European Union, 2010

    2010-01-01

    TEMPUS is a European Union funded Programme which supports the modernisation of higher education in the Partner Countries in Eastern Europe, Central Asia, the Western Balkans and the Mediterranean region, mainly through university cooperation projects. It also aims to promote the voluntary convergence of the higher education systems in the Partner…

  7. Research on English Language Teaching and Learning in Argentina (2007-2013)

    ERIC Educational Resources Information Center

    Porto, Melina; Montemayor-Borsinger, Ann; López-Barrios, Mario

    2016-01-01

    In this article we review research on English as a foreign language (EFL) teaching and learning published in Argentina between 2007 and 2013. This is the first review of a Latin American country in this series. Argentina has a century-long tradition of training EFL teachers but a comparatively shorter though fruitful history of foreign language…

  8. Blueprint for a Coastal Legacy: Connecticut Sea Grant Strategic Plan 2007-2013

    ERIC Educational Resources Information Center

    Connecticut Sea Grant (NJ1), 2009

    2009-01-01

    For nearly 20 years, the Connecticut Sea Grant College Program (CTSG) has worked to foster the wise use and conservation of coastal and marine resources of the Long Island Sound (LIS) estuary, as well as working regionally, nationally and globally. The strategy for success of any individual Sea Grant College Program must be consistent with the…

  9. The Spanish Renal Registry: 2013 report and evolution from 2007-2013.

    PubMed

    Martín Escobar, Eduardo

    2016-01-01

    The purpose of the study is to show the evolution of renal replacement therapy (RRT) in Spain from 2007 to 2013. Aggregated data and individual patient records were used from participating regional renal disease registries and that National Transplant Organisation registry. The reference population was the official population on January 1st of each year studied. Data on incidence and prevalence were based on aggregated data, while the survival analysis was calculated from individual patient records. The study period was 2007 to 2013 for prevalence, incidence and transplantation, and survival was analysed for 2004-2012. The population covered by the registry was a minimum of 95.3% to 100% of the Spanish population for aggregated data. The EU27 age and gender distributions of the European population for 2005 were used to adjust incidence and prevalence for age and gender. Survival probabilities were calculated for incident patients between the years 2004 and 2013 using the Kaplan-Meier method to calculate unadjusted patient survival probability. The log rank test was applied to compare survival curves according to some risk factors. Cox proportional hazards model was created to study the potential predictors of survival. In 2013, the total number of patients in Spain that started RRT was 5,705 for 95.3% of the total Spanish population, with an unadjusted rate of 127.1pmp. The evolution from 2007 to 2013 showed a gradual decline from 127.4pmp in 2007 to 120.4pmp in 2012, with a small upturn to 127.1 in 2013. The adjusted incidence rate for the year 2013 was 121.5pmp for the total population, 158.7pmp for males and 83.1pmp for females. The most frequent cause of primary renal disease in incident was diabetes mellitus: 20.4% in 2007, which increased to 24.6% in 2013. The percentage of transplant as first RRT increased from 1.7% in 2007 to 4.2% in 2013. The total number of patients in RRT for 95.3% of the population in 2013 was 50,567, with an unadjusted prevalent rate of 1,125.7pmp. The adjusted prevalence rate for 2013 was 1,087.5 pmp (1,360.7 pmp for males and 809.8pmp for females). The percentage of diabetes mellitus in prevalent patients evolved from 13.9% in 2007 to 14.9% (168 pmp) in 2013. The percentage of transplanted prevalent patients with functioning grafts evolved from 49.3% in 2007 to 51.5% in 2013. The number of transplantations performed each year increased from 2,211 (48.9 pmp) in 2007 (6.2% living donor transplants) to 2,552 (54.2pmp) in 2013 (15.0% living donor transplants). 40,394 patients from 12 regions of Spain who began RRT between 2004 and 2012 were included in the survival analysis (87% Spanish population coverage). Unadjusted patient survival probabilities after one, 2 and 5 years were 91, 81 and 57%, respectively. In the univariate analysis, better survival was found for non-diabetic patients, women, age below 45, peritoneal dialysis as first RRT and patients who had received at least one transplant.

  10. FDA Safety Reviews on Drugs, Biologics, and Vaccines: 2007-2013.

    PubMed

    Cope, Judith U; Rosenthal, Geoffrey L; Weinel, Pamela; Odegaard, Amy; Murphy, Dianne M

    2015-12-01

    In 2002, Congress mandated that the US Food and Drug Administration (FDA) monitor postmarketing pediatric adverse events and present safety reports to the FDA's Pediatric Advisory Committee (PAC). These safety reviews play a critical role in the postmarketing surveillance and identification of pediatric safety issues. This article follows a previous review ending in 2007 and summarizes 6 years of recent pediatric safety reporting, recommendations by the PAC, and actions by the FDA, including labeling changes. An analysis of the FDA's PAC safety reviews performed from November 2007 through September 2013 was conducted. PAC recommendations for subsequent labeling changes, future studies, or other safety issues were reviewed. There were 6930 serious adverse event reports in 181 reviews. These findings resulted in 33 (18%) recommended labeling changes, and 21 (64%) of these changes were adopted. For 10 products, information was added to the Warning and Precautions section of the label. The PAC also discussed or recommended additional studies for certain products. This article highlights the importance of the FDA's ongoing pediatric postmarketing safety reviews of regulated products, advice from the PAC, and FDA actions in the best interest of pediatric patients. This mandated process facilitates detection of safety concerns that may not be identified in prelicensure clinical trials. It continues to identify critical safety concerns, including unlabeled adverse events, frequent off-label use, product misuse, and secondary exposures in children. Copyright © 2015 by the American Academy of Pediatrics.

  11. A Comparative Review of Waivers Granted in Pediatric Drug Development by FDA and EMA from 2007-2013

    PubMed Central

    Egger, Gunter F.; Wharton, Gerold T.; Malli, Suzanne; Temeck, Jean; Murphy, M. Dianne; Tomasi, Paolo

    2016-01-01

    Background The European Union and the United States have different legal frameworks in place for pediatric drug development, which can potentially lead to different pediatric research requirements for the pharmaceutical industry. This manuscript compares pediatric clinical trial waivers granted by the European Medicines Agency (EMA) and the US Food and Drug Administration (FDA). Methods This is a retrospective review comparing EMA’s Paediatric Committee (PDCO) decisions with FDA’s Pediatric Review Committee (PeRC) recommendations for all product-specific pediatric full waiver applications submitted to EMA from January 2007 through December 2013. Using baseline data from EMA, we matched product-specific waivers with their FDA equivalents during the study period. Results For single active substance products, PDCO and PeRC adopted similar opinions in 42 of 49 indications (86%). For fixed-dose combinations, PDCO and PeRC adopted similar opinions in 24 of 31 indications (77%). Conclusion Despite the different legal frameworks, criteria, and processes of determination, the waiver decisions of the 2 agencies were similar in the majority of cases. PMID:27274951

  12. Search for transient gravitational waves in coincidence with short-duration radio transients during 2007-2013

    NASA Astrophysics Data System (ADS)

    Abbott, B. P.; Abbott, R.; Abbott, T. D.; Abernathy, M. R.; Acernese, F.; Ackley, K.; Adams, C.; Adams, T.; Addesso, P.; Adhikari, R. X.; Adya, V. B.; Affeldt, C.; Agathos, M.; Agatsuma, K.; Aggarwal, N.; Aguiar, O. D.; Aiello, L.; Ain, A.; Ajith, P.; Allen, B.; Allocca, A.; Altin, P. A.; Anderson, S. B.; Anderson, W. G.; Arai, K.; Araya, M. C.; Arceneaux, C. C.; Areeda, J. S.; Arnaud, N.; Arun, K. G.; Ascenzi, S.; Ashton, G.; Ast, M.; Aston, S. M.; Astone, P.; Aufmuth, P.; Aulbert, C.; Babak, S.; Bacon, P.; Bader, M. K. M.; Baker, P. T.; Baldaccini, F.; Ballardin, G.; Ballmer, S. W.; Barayoga, J. C.; Barclay, S. E.; Barish, B. C.; Barker, D.; Barone, F.; Barr, B.; Barsotti, L.; Barsuglia, M.; Barta, D.; Bartlett, J.; Bartos, I.; Bassiri, R.; Basti, A.; Batch, J. C.; Baune, C.; Bavigadda, V.; Bazzan, M.; Behnke, B.; Bejger, M.; Bell, A. S.; Bell, C. J.; Berger, B. K.; Bergman, J.; Bergmann, G.; Berry, C. P. L.; Bersanetti, D.; Bertolini, A.; Betzwieser, J.; Bhagwat, S.; Bhandare, R.; Bilenko, I. A.; Billingsley, G.; Birch, J.; Birney, R.; Biscans, S.; Bisht, A.; Bitossi, M.; Biwer, C.; Bizouard, M. A.; Blackburn, J. K.; Blair, C. D.; Blair, D. G.; Blair, R. M.; Bloemen, S.; Bock, O.; Bodiya, T. P.; Boer, M.; Bogaert, G.; Bogan, C.; Bohe, A.; Bojtos, P.; Bond, C.; Bondu, F.; Bonnand, R.; Boom, B. A.; Bork, R.; Boschi, V.; Bose, S.; Bouffanais, Y.; Bozzi, A.; Bradaschia, C.; Brady, P. R.; Braginsky, V. B.; Branchesi, M.; Brau, J. E.; Briant, T.; Brillet, A.; Brinkmann, M.; Brisson, V.; Brockill, P.; Brooks, A. F.; Brown, D. A.; Brown, D. D.; Brown, N. M.; Buchanan, C. C.; Buikema, A.; Bulik, T.; Bulten, H. J.; Buonanno, A.; Buskulic, D.; Buy, C.; Byer, R. L.; Cadonati, L.; Cagnoli, G.; Cahillane, C.; Calderón Bustillo, J.; Callister, T.; Calloni, E.; Camp, J. B.; Cannon, K. C.; Cao, J.; Capano, C. D.; Capocasa, E.; Carbognani, F.; Caride, S.; Casanueva Diaz, J.; Casentini, C.; Caudill, S.; Cavaglià, M.; Cavalier, F.; Cavalieri, R.; Cella, G.; Cepeda, C. B.; Cerboni Baiardi, L.; Cerretani, G.; Cesarini, E.; Chakraborty, R.; Chalermsongsak, T.; Chamberlin, S. J.; Chan, M.; Chao, S.; Charlton, P.; Chassande-Mottin, E.; Chen, H. Y.; Chen, Y.; Cheng, C.; Chincarini, A.; Chiummo, A.; Cho, H. S.; Cho, M.; Chow, J. H.; Christensen, N.; Chu, Q.; Chua, S.; Chung, S.; Ciani, G.; Clara, F.; Clark, J. A.; Cleva, F.; Coccia, E.; Cohadon, P.-F.; Colla, A.; Collette, C. G.; Cominsky, L.; Constancio, M.; Conte, A.; Conti, L.; Cook, D.; Corbitt, T. R.; Cornish, N.; Corsi, A.; Cortese, S.; Costa, C. A.; Coughlin, M. W.; Coughlin, S. B.; Coulon, J.-P.; Countryman, S. T.; Couvares, P.; Coward, D. M.; Cowart, M. J.; Coyne, D. C.; Coyne, R.; Craig, K.; Creighton, J. D. E.; Cripe, J.; Crowder, S. G.; Cumming, A.; Cunningham, L.; Cuoco, E.; Dal Canton, T.; Danilishin, S. L.; D'Antonio, S.; Danzmann, K.; Darman, N. S.; Dattilo, V.; Dave, I.; Daveloza, H. P.; Davier, M.; Davies, G. S.; Daw, E. J.; Day, R.; DeBra, D.; Debreczeni, G.; Degallaix, J.; De Laurentis, M.; Deléglise, S.; Del Pozzo, W.; Denker, T.; Dent, T.; Dergachev, V.; De Rosa, R.; DeRosa, R. T.; DeSalvo, R.; Dhurandhar, S.; Díaz, M. C.; Di Fiore, L.; Di Giovanni, M.; Di Girolamo, T.; Di Lieto, A.; Di Pace, S.; Di Palma, I.; Di Virgilio, A.; Dojcinoski, G.; Dolique, V.; Donovan, F.; Dooley, K. L.; Doravari, S.; Douglas, R.; Downes, T. P.; Drago, M.; Drever, R. W. P.; Driggers, J. C.; Du, Z.; Ducrot, M.; Dwyer, S. E.; Edo, T. B.; Edwards, M. C.; Effler, A.; Eggenstein, H.-B.; Ehrens, P.; Eichholz, J.; Eikenberry, S. S.; Engels, W.; Essick, R. C.; Etzel, T.; Evans, M.; Evans, T. M.; Everett, R.; Factourovich, M.; Fafone, V.; Fair, H.; Fairhurst, S.; Fan, X.; Fang, Q.; Farinon, S.; Farr, B.; Farr, W. M.; Favata, M.; Fays, M.; Fehrmann, H.; Fejer, M. M.; Ferrante, I.; Ferreira, E. C.; Ferrini, F.; Fidecaro, F.; Fiori, I.; Fiorucci, D.; Fisher, R. P.; Flaminio, R.; Fletcher, M.; Fournier, J.-D.; Frasca, S.; Frasconi, F.; Frei, Z.; Freise, A.; Frey, R.; Frey, V.; Fricke, T. T.; Fritschel, P.; Frolov, V. V.; Fulda, P.; Fyffe, M.; Gabbard, H. A. G.; Gair, J. R.; Gammaitoni, L.; Gaonkar, S. G.; Garufi, F.; Gaur, G.; Gehrels, N.; Gemme, G.; Genin, E.; Gennai, A.; George, J.; Gergely, L.; Germain, V.; Ghosh, Archisman; Ghosh, S.; Giaime, J. A.; Giardina, K. D.; Giazotto, A.; Gill, K.; Glaefke, A.; Goetz, E.; Goetz, R.; Gondan, L.; González, G.; Gonzalez Castro, J. M.; Gopakumar, A.; Gordon, N. A.; Gorodetsky, M. L.; Gossan, S. E.; Gosselin, M.; Gouaty, R.; Grado, A.; Graef, C.; Graff, P. B.; Granata, M.; Grant, A.; Gras, S.; Gray, C.; Greco, G.; Green, A. C.; Groot, P.; Grote, H.; Grunewald, S.; Guidi, G. M.; Guo, X.; Gupta, A.; Gupta, M. K.; Gushwa, K. E.; Gustafson, E. K.; Gustafson, R.; Hacker, J. J.; Hall, B. R.; Hall, E. D.; Hammond, G.; Haney, M.; Hanke, M. M.; Hanks, J.; Hanna, C.; Hannam, M. D.; Hanson, J.; Hardwick, T.; Harms, J.; Harry, G. M.; Harry, I. W.; Hart, M. J.; Hartman, M. T.; Haster, C.-J.; Haughian, K.; Heidmann, A.; Heintze, M. C.; Heitmann, H.; Hello, P.; Hemming, G.; Hendry, M.; Heng, I. S.; Hennig, J.; Heptonstall, A. W.; Heurs, M.; Hild, S.; Hoak, D.; Hodge, K. A.; Hofman, D.; Hollitt, S. E.; Holt, K.; Holz, D. E.; Hopkins, P.; Hosken, D. J.; Hough, J.; Houston, E. A.; Howell, E. J.; Hu, Y. M.; Huang, S.; Huerta, E. A.; Huet, D.; Hughey, B.; Husa, S.; Huttner, S. H.; Huynh-Dinh, T.; Idrisy, A.; Indik, N.; Ingram, D. R.; Inta, R.; Isa, H. N.; Isac, J.-M.; Isi, M.; Islas, G.; Isogai, T.; Iyer, B. R.; Izumi, K.; Jacqmin, T.; Jang, H.; Jani, K.; Jaranowski, P.; Jawahar, S.; Jiménez-Forteza, F.; Johnson, W. W.; Jones, D. I.; Jones, R.; Jonker, R. J. G.; Ju, L.; Haris, K.; Kalaghatgi, C. V.; Kalogera, V.; Kandhasamy, S.; Kang, G.; Kanner, J. B.; Karki, S.; Kasprzack, M.; Katsavounidis, E.; Katzman, W.; Kaufer, S.; Kaur, T.; Kawabe, K.; Kawazoe, F.; Kéfélian, F.; Kehl, M. S.; Keitel, D.; Kelley, D. B.; Kells, W.; Kennedy, R.; Key, J. S.; Khalaidovski, A.; Khalili, F. Y.; Khan, I.; Khan, S.; Khan, Z.; Khazanov, E. A.; Kijbunchoo, N.; Kim, Chunglee; Kim, J.; Kim, K.; Kim, Nam-Gyu; Kim, Namjun; Kim, Y.-M.; King, E. J.; King, P. J.; Kinzel, D. L.; Kissel, J. S.; Kleybolte, L.; Klimenko, S.; Koehlenbeck, S. M.; Kokeyama, K.; Koley, S.; Kondrashov, V.; Kontos, A.; Korobko, M.; Korth, W. Z.; Kowalska, I.; Kozak, D. B.; Kringel, V.; Królak, A.; Krueger, C.; Kuehn, G.; Kumar, P.; Kuo, L.; Kutynia, A.; Lackey, B. D.; Landry, M.; Lange, J.; Lantz, B.; Lasky, P. D.; Lazzarini, A.; Lazzaro, C.; Leaci, P.; Leavey, S.; Lebigot, E. O.; Lee, C. H.; Lee, H. K.; Lee, H. M.; Lee, K.; Lenon, A.; Leonardi, M.; Leong, J. R.; Leroy, N.; Letendre, N.; Levin, Y.; Levine, B. M.; Li, T. G. F.; Libson, A.; Littenberg, T. B.; Lockerbie, N. A.; Logue, J.; Lombardi, A. L.; Lord, J. E.; Lorenzini, M.; Loriette, V.; Lormand, M.; Losurdo, G.; Lough, J. D.; Lück, H.; Lundgren, A. P.; Luo, J.; Lynch, R.; Ma, Y.; MacDonald, T.; Machenschalk, B.; MacInnis, M.; Macleod, D. M.; Magaña-Sandoval, F.; Magee, R. M.; Mageswaran, M.; Majorana, E.; Maksimovic, I.; Malvezzi, V.; Man, N.; Mandic, V.; Mangano, V.; Mansell, G. L.; Manske, M.; Mantovani, M.; Marchesoni, F.; Marion, F.; Márka, S.; Márka, Z.; Markosyan, A. S.; Maros, E.; Martelli, F.; Martellini, L.; Martin, I. W.; Martin, R. M.; Martynov, D. V.; Marx, J. N.; Mason, K.; Masserot, A.; Massinger, T. J.; Masso-Reid, M.; Mastrogiovanni, S.; Matichard, F.; Matone, L.; Mavalvala, N.; Mazumder, N.; Mazzolo, G.; McCarthy, R.; McClelland, D. E.; McCormick, S.; McGuire, S. C.; McIntyre, G.; McIver, J.; McManus, D. J.; McWilliams, S. T.; Meacher, D.; Meadors, G. D.; Meidam, J.; Melatos, A.; Mendell, G.; Mendoza-Gandara, D.; Mercer, R. A.; Merilh, E. L.; Merzougui, M.; Meshkov, S.; Messenger, C.; Messick, C.; Metzdorff, R.; Meyers, P. M.; Mezzani, F.; Miao, H.; Michel, C.; Middleton, H.; Mikhailov, E. E.; Milano, L.; Miller, A. L.; Miller, J.; Millhouse, M.; Minenkov, Y.; Ming, J.; Mirshekari, S.; Mishra, C.; Mitra, S.; Mitrofanov, V. P.; Mitselmakher, G.; Mittleman, R.; Moggi, A.; Mohan, M.; Mohapatra, S. R. P.; Montani, M.; Moore, B. C.; Moore, C. J.; Moraru, D.; Moreno, G.; Morriss, S. R.; Mossavi, K.; Mours, B.; Mow-Lowry, C. M.; Mueller, C. L.; Mueller, G.; Muir, A. W.; Mukherjee, Arunava; Mukherjee, D.; Mukherjee, S.; Mukund, K. N.; Mullavey, A.; Munch, J.; Murphy, D. J.; Murray, P. G.; Mytidis, A.; Nardecchia, I.; Naticchioni, L.; Nayak, R. K.; Necula, V.; Nedkova, K.; Nelemans, G.; Neri, M.; Neunzert, A.; Newton, G.; Nguyen, T. T.; Nielsen, A. B.; Nissanke, S.; Nitz, A.; Nocera, F.; Nolting, D.; Normandin, M. E. N.; Nuttall, L. K.; Oberling, J.; Ochsner, E.; O'Dell, J.; Oelker, E.; Ogin, G. H.; Oh, J. J.; Oh, S. H.; Ohme, F.; Oliver, M.; Oppermann, P.; Oram, Richard J.; O'Reilly, B.; O'Shaughnessy, R.; Ott, C. D.; Ottaway, D. J.; Ottens, R. S.; Overmier, H.; Owen, B. J.; Pai, A.; Pai, S. A.; Palamos, J. R.; Palashov, O.; Palomba, C.; Pal-Singh, A.; Pan, H.; Pankow, C.; Pannarale, F.; Pant, B. C.; Paoletti, F.; Paoli, A.; Papa, M. A.; Paris, H. R.; Parker, W.; Pascucci, D.; Pasqualetti, A.; Passaquieti, R.; Passuello, D.; Patricelli, B.; Patrick, Z.; Pearlstone, B. L.; Pedraza, M.; Pedurand, R.; Pekowsky, L.; Pele, A.; Penn, S.; Pereira, R.; Perreca, A.; Phelps, M.; Piccinni, O. J.; Pichot, M.; Piergiovanni, F.; Pierro, V.; Pillant, G.; Pinard, L.; Pinto, I. M.; Pitkin, M.; Pletsch, H. J.; Poggiani, R.; Popolizio, P.; Post, A.; Powell, J.; Prasad, J.; Predoi, V.; Premachandra, S. S.; Prestegard, T.; Price, L. R.; Prijatelj, M.; Principe, M.; Privitera, S.; Prodi, G. A.; Prokhorov, L.; Puncken, O.; Punturo, M.; Puppo, P.; Pürrer, M.; Qi, H.; Qin, J.; Quetschke, V.; Quintero, E. A.; Quitzow-James, R.; Raab, F. J.; Rabeling, D. S.; Radkins, H.; Raffai, P.; Raja, S.; Rakhmanov, M.; Rapagnani, P.; Raymond, V.; Razzano, M.; Re, V.; Read, J.; Reed, C. M.; Regimbau, T.; Rei, L.; Reid, S.; Reitze, D. H.; Rew, H.; Ricci, F.; Riles, K.; Robertson, N. A.; Robie, R.; Robinet, F.; Rocchi, A.; Rolland, L.; Rollins, J. G.; Roma, V. J.; Romano, J. D.; Romano, R.; Romanov, G.; Romie, J. H.; Rosińska, D.; Rowan, S.; Rüdiger, A.; Ruggi, P.; Ryan, K.; Sachdev, S.; Sadecki, T.; Sadeghian, L.; Salconi, L.; Saleem, M.; Salemi, F.; Samajdar, A.; Sammut, L.; Sanchez, E. J.; Sandberg, V.; Sandeen, B.; Sanders, J. R.; Sassolas, B.; Sathyaprakash, B. S.; Saulson, P. R.; Sauter, O. E. S.; Savage, R. L.; Sawadsky, A.; Schale, P.; Schilling, R.; Schmidt, J.; Schmidt, P.; Schnabel, R.; Schofield, R. M. S.; Schönbeck, A.; Schreiber, E.; Schuette, D.; Schutz, B. F.; Scott, J.; Scott, S. M.; Sellers, D.; Sentenac, D.; Sequino, V.; Sergeev, A.; Serna, G.; Setyawati, Y.; Sevigny, A.; Shaddock, D. A.; Shahriar, M. S.; Shaltev, M.; Shao, Z.; Shapiro, B.; Shawhan, P.; Sheperd, A.; Shoemaker, D. H.; Shoemaker, D. M.; Siellez, K.; Siemens, X.; Sieniawska, M.; Sigg, D.; Silva, A. D.; Simakov, D.; Singer, A.; Singer, L. P.; Singh, A.; Singh, R.; Singhal, A.; Sintes, A. M.; Slagmolen, B. J. J.; Smith, J. R.; Smith, N. D.; Smith, R. J. E.; Son, E. J.; Sorazu, B.; Sorrentino, F.; Souradeep, T.; Srivastava, A. K.; Staley, A.; Steinke, M.; Steinlechner, J.; Steinlechner, S.; Steinmeyer, D.; Stephens, B. C.; Stiles, D.; Stone, R.; Strain, K. A.; Straniero, N.; Stratta, G.; Strauss, N. A.; Strigin, S.; Sturani, R.; Stuver, A. L.; Summerscales, T. Z.; Sun, L.; Sutton, P. J.; Swinkels, B. L.; Szczepańczyk, M. J.; Tacca, M.; Talukder, D.; Tanner, D. B.; Tápai, M.; Tarabrin, S. P.; Taracchini, A.; Taylor, R.; Theeg, T.; Thirugnanasambandam, M. P.; Thomas, E. G.; Thomas, M.; Thomas, P.; Thorne, K. A.; Thrane, E.; Tiwari, S.; Tiwari, V.; Tokmakov, K. V.; Tomlinson, C.; Tonelli, M.; Torres, C. V.; Torrie, C. I.; Töyrä, D.; Travasso, F.; Traylor, G.; Trifirò, D.; Tringali, M. C.; Trozzo, L.; Tse, M.; Turconi, M.; Tuyenbayev, D.; Ugolini, D.; Unnikrishnan, C. S.; Urban, A. L.; Usman, S. A.; Vahlbruch, H.; Vajente, G.; Valdes, G.; van Bakel, N.; van Beuzekom, M.; van den Brand, J. F. J.; Van Den Broeck, C.; Vander-Hyde, D. C.; van der Schaaf, L.; van Heijningen, J. V.; van Veggel, A. A.; Vardaro, M.; Vass, S.; Vasúth, M.; Vaulin, R.; Vecchio, A.; Vedovato, G.; Veitch, J.; Veitch, P. J.; Venkateswara, K.; Verkindt, D.; Vetrano, F.; Viceré, A.; Vinciguerra, S.; Vine, D. J.; Vinet, J.-Y.; Vitale, S.; Vo, T.; Vocca, H.; Vorvick, C.; Voss, D. V.; Vousden, W. D.; Vyatchanin, S. P.; Wade, A. R.; Wade, L. E.; Wade, M.; Walker, M.; Wallace, L.; Walsh, S.; Wang, G.; Wang, H.; Wang, M.; Wang, X.; Wang, Y.; Ward, R. L.; Warner, J.; Was, M.; Weaver, B.; Wei, L.-W.; Weinert, M.; Weinstein, A. J.; Weiss, R.; Welborn, T.; Wen, L.; Weßels, P.; Westphal, T.; Wette, K.; Whelan, J. T.; Whitcomb, S. E.; White, D. J.; Whiting, B. F.; Williams, R. D.; Williamson, A. R.; Willis, J. L.; Willke, B.; Wimmer, M. H.; Winkler, W.; Wipf, C. C.; Wittel, H.; Woan, G.; Worden, J.; Wright, J. L.; Wu, G.; Yablon, J.; Yam, W.; Yamamoto, H.; Yancey, C. C.; Yap, M. J.; Yu, H.; Yvert, M.; ZadroŻny, A.; Zangrando, L.; Zanolin, M.; Zendri, J.-P.; Zevin, M.; Zhang, F.; Zhang, L.; Zhang, M.; Zhang, Y.; Zhao, C.; Zhou, M.; Zhou, Z.; Zhu, X. J.; Zucker, M. E.; Zuraw, S. E.; Zweizig, J.; Archibald, A. M.; Banaszak, S.; Berndsen, A.; Boyles, J.; Cardoso, R. F.; Chawla, P.; Cherry, A.; Dartez, L. P.; Day, D.; Epstein, C. R.; Ford, A. J.; Flanigan, J.; Garcia, A.; Hessels, J. W. T.; Hinojosa, J.; Jenet, F. A.; Karako-Argaman, C.; Kaspi, V. M.; Keane, E. F.; Kondratiev, V. I.; Kramer, M.; Leake, S.; Lorimer, D.; Lunsford, G.; Lynch, R. S.; Martinez, J. G.; Mata, A.; McLaughlin, M. A.; McPhee, C. A.; Penucci, T.; Ransom, S.; Roberts, M. S. E.; Rohr, M. D. W.; Stairs, I. H.; Stovall, K.; van Leeuwen, J.; Walker, A. N.; Wells, B. L.; LIGO Scientific Collaboration; Virgo Collaboration

    2016-06-01

    We present an archival search for transient gravitational-wave bursts in coincidence with 27 single-pulse triggers from Green Bank Telescope pulsar surveys, using the LIGO, Virgo, and GEO interferometer network. We also discuss a check for gravitational-wave signals in coincidence with Parkes fast radio bursts using similar methods. Data analyzed in these searches were collected between 2007 and 2013. Possible sources of emission of both short-duration radio signals and transient gravitational-wave emission include starquakes on neutron stars, binary coalescence of neutron stars, and cosmic string cusps. While no evidence for gravitational-wave emission in coincidence with these radio transients was found, the current analysis serves as a prototype for similar future searches using more sensitive second-generation interferometers.

  13. Considering Teaching Excellence in Higher Education: 2007-2013. A Literature Review since the CHERI Report 2007. HEA Research Series

    ERIC Educational Resources Information Center

    Gunn, Vicky; Fisk, Anna

    2014-01-01

    This research review explores both the research and the grey literature on university teaching excellence with a specific remit to update an earlier review, "Excellence in Teaching and Learning: a review of literature for the Higher Education Academy". Little, B., et al (2007) The two main aims are: (1) to suggest further areas of…

  14. Prevalence of Comorbidity among People with Hypertension: The Korea National Health and Nutrition Examination Survey 2007-2013

    PubMed Central

    Noh, Juhwan; Shin, Anna; Yeom, Hyungseon; Jang, Suk-Yong; Lee, Jung Hyun; Kim, Changsoo; Suh, Il

    2016-01-01

    Background and Objectives Joint National Committee guidelines attempt to vary treatment recommendations for patients based on considerations of their comorbidities. The aim of the present study is to estimate the age-standardized prevalence of common comorbidities among Korean hypertension patients. Subjects and Methods We analyzed the Korea National Health and Nutrition Examination Survey from 2007 to 2013. Among the 58423 participants, 30092 adults, aged ≥30 yrs who completed a health examination and interview survey, were selected. The survey procedures were used to estimate weighted prevalence and odds ratios for 8 comorbidities, including obesity, diabetes mellitus, dyslipidemia, cardiovascular disease, chronic kidney disease, and thyroid disease. Results Most chronic conditions were more prevalent in adults with hypertension than in those without hypertension. Common comorbidities were obesity (60.1%), dyslipidemia (57.6%), and impaired fasting glucose (45.1%). Hypertensive patients with two or more comorbid diseases were 42.2% and those with three or more diseases were 17.7%. The age- and sex-specific prevalence of three or more comorbid diseases among male hypertension patients was significantly higher than those patients in the 30-59 (p<0.05) age group. Conclusion Comorbidity is highly prevalent in Korean patients with hypertension. PMID:27721859

  15. Video documentation of experiments at the USGS debris-flow flume 1992–2006 (amended to include 2007-2013)

    USGS Publications Warehouse

    Logan, Matthew; Iverson, Richard M.

    2007-01-01

    This set of videos presents about 15 hours of footage documenting the 141 experiments conducted at the USGS debris-flow flume from 1992 to 2012. Owing to improvements in video technology over the years, the quality of footage from recent experiments generally exceeds that from earlier experiments. Use the list below to access the individual videos, which are grouped by year and listed by date and subject matter. When an experiment is selected from the list, multiple video sequences are automatically shown in succession, beginning with a far-field overview and proceeding to close-up views and post-experiment documentation. Interpretations and data from experiments at the USGS debris-flow flume are not provided here but can be found in published reports, many of which are available online at: https://profile.usgs.gov/riverson/ A brief introduction to the flume facility is also available online in USGS Open-File Report 92–483 [http://pubs.er.usgs.gov/usgspubs/ofr/ofr92483].

  16. Environmental surveillance of poliovirus and non-polio enterovirus in urban sewage in Dakar, Senegal (2007-2013)

    PubMed Central

    Ndiaye, Abdou Kader; Diop, Pape Amadou Mbathio; Diop, Ousmane Madiagne

    2014-01-01

    Introduction Global poliomyelitis eradication initiative relies on (i) laboratory based surveillance of acute flaccid surveillance (AFP) to monitor the circulation of wild poliovirus in a population, and (ii) vaccination to prevent its diffusion. However, as poliovirus can survive in the environment namely in sewage, environmental surveillance (ES) is of growing importance as the eradication target is close. This study aimed to assess polioviruses and non polio enteroviruses circulation in sewage drains covering a significant population of Dakar. Methods From April 2007 to May 2013, 271 specimens of raw sewage were collected using the grab method in 6 neighborhoods of Dakar. Samples were processed to extract and concentrate viruses using polyethylene glycol and Dextran (two-phase separation method). Isolation of enteroviruses was attempted in RD, L20B and Hep2 cell lines. Polioviruses were identified by RT-PCR and Elisa. Non Polio Enteroviruses (NPEVs) were identified by RT-PCR and microneutralisation tests. Results Polioviruses and NPEVs were respectively detected in 34,3% and 42,8% sewage samples. No wild poliovirus neither circulating vaccine-derived Poliovirus (cVDPV) was detected. Neutralization assays have identified 49 non polio enteroviruses that were subsequently classified in 13 serotypes belonging to HEV-A (22, 4%), HEV-B (12, 24%), HEV-C (26, 53%) and HEV-D (6, 12%) species. Conclusion This study is the first documentation of enteroviruses environmental detection in Senegal. It shows the usefulness of environmental surveillance for indirect monitoring of the circulation and distribution of enteroviruses in the community. PMID:25848458

  17. Sleep Duration and Injury-Related Risk Behaviors Among High School Students--United States, 2007-2013.

    PubMed

    Wheaton, Anne G; Olsen, Emily O'Malley; Miller, Gabrielle F; Croft, Janet B

    2016-04-08

    Insufficient sleep is common among high school students and has been associated with an increased risk for motor vehicle crashes (1), sports injuries (2), and occupational injuries (3). To evaluate the association between self-reported sleep duration on an average school night and several injury-related risk behaviors (infrequent bicycle helmet use, infrequent seatbelt use, riding with a driver who had been drinking, drinking and driving, and texting while driving) among U.S. high school students, CDC analyzed data from 50,370 high school students (grades 9-12) who participated in the national Youth Risk Behavior Surveys (YRBSs) in 2007, 2009, 2011, or 2013. The likelihood of each of the five risk behaviors was significantly higher for students who reported sleeping ≤7 hours on an average school night; infrequent seatbelt use, riding with a drinking driver, and drinking and driving were also more likely for students who reported sleeping ≥10 hours compared with 9 hours on an average school night. Although insufficient sleep directly contributes to injury risk, some of the increased risk associated with insufficient sleep might be caused by engaging in injury-related risk behaviors. Intervention efforts aimed at these behaviors might help reduce injuries resulting from sleepiness, as well as provide opportunities for increasing awareness of the importance of sleep.

  18. Considering Teaching Excellence in Higher Education: 2007-2013. A Literature Review since the CHERI Report 2007. HEA Research Series

    ERIC Educational Resources Information Center

    Gunn, Vicky; Fisk, Anna

    2014-01-01

    This research review explores both the research and the grey literature on university teaching excellence with a specific remit to update an earlier review, "Excellence in Teaching and Learning: a review of literature for the Higher Education Academy". Little, B., et al (2007) The two main aims are: (1) to suggest further areas of…

  19. Environmental surveillance of poliovirus and non-polio enterovirus in urban sewage in Dakar, Senegal (2007-2013).

    PubMed

    Ndiaye, Abdou Kader; Diop, Pape Amadou Mbathio; Diop, Ousmane Madiagne

    2014-01-01

    Global poliomyelitis eradication initiative relies on (i) laboratory based surveillance of acute flaccid surveillance (AFP) to monitor the circulation of wild poliovirus in a population, and (ii) vaccination to prevent its diffusion. However, as poliovirus can survive in the environment namely in sewage, environmental surveillance (ES) is of growing importance as the eradication target is close. This study aimed to assess polioviruses and non polio enteroviruses circulation in sewage drains covering a significant population of Dakar. From April 2007 to May 2013, 271 specimens of raw sewage were collected using the grab method in 6 neighborhoods of Dakar. Samples were processed to extract and concentrate viruses using polyethylene glycol and Dextran (two-phase separation method). Isolation of enteroviruses was attempted in RD, L20B and Hep2 cell lines. Polioviruses were identified by RT-PCR and Elisa. Non Polio Enteroviruses (NPEVs) were identified by RT-PCR and microneutralisation tests. Polioviruses and NPEVs were respectively detected in 34,3% and 42,8% sewage samples. No wild poliovirus neither circulating vaccine-derived Poliovirus (cVDPV) was detected. Neutralization assays have identified 49 non polio enteroviruses that were subsequently classified in 13 serotypes belonging to HEV-A (22, 4%), HEV-B (12, 24%), HEV-C (26, 53%) and HEV-D (6, 12%) species. This study is the first documentation of enteroviruses environmental detection in Senegal. It shows the usefulness of environmental surveillance for indirect monitoring of the circulation and distribution of enteroviruses in the community.

  20. Search for Transient Gravitational Waves in Coincidence with Short-Duration Radio Transients During 2007-2013

    NASA Technical Reports Server (NTRS)

    Abbott, B. P.; Hughey, Brennan; Zanolin, Michele; Szczepanczyk, Marek; Gill, Kiranjyot; Abbott, R.; Abbott, T. D.; Abernathy, M. R.; Acernese, F.; Ackley, K.; hide

    2016-01-01

    We present an archival search for transient gravitational-wave bursts in coincidence with 27 single-pulse triggers from Green Bank Telescope pulsar surveys, using the LIGO (Laser Interferometer Gravitational Wave Observatory), Virgo (Variability of Solar Irradiance and Gravity Oscillations) and GEO (German-UK Interferometric Detector) interferometer network. We also discuss a check for gravitational-wave signals in coincidence with Parkes fast radio bursts using similar methods. Data analyzed in these searches were collected between 2007 and 2013. Possible sources of emission of both short-duration radio signals and transient gravitational-wave emission include star quakes on neutron stars, binary coalescence of neutron stars, and cosmic string cusps. While no evidence for gravitational-wave emission in coincidence with these radio transients was found, the current analysis serves as a prototype for similar future searches using more sensitive second-generation interferometers.

  1. Prevalence of pollinosis in patients with allergic asthma, rhinitis and conjunctivitis in the South of Mexico City 2007-2013.

    PubMed

    Gaspar-López, Arturo; López-Rocha, Eunice; Rodríguez-Mireles, Karen; Segura-Méndez, Nora; Del Rivero-Hernández, Leonel

    2014-01-01

    Antecedentes: la prevalencia de la polinosis se ha duplicado en las últimas dos décadas. Diversos estudios sugieren que incluso 50% de los adultos residentes del Distrito Federal pueden tener datos de alergia respiratoria y que los pólenes de árboles, pastos y malezas constituyen una causa frecuente. Conocer la prevalencia de sus familias y cruces antigénicos permite ofrecer diagnósticos y tratamientos adecuados. Objetivo: conocer la prevalencia de sensibilización a pólenes de árboles, gramíneas y malezas en adultos con alergia respiratoria de la zona sur del Distrito Federal en el periodo de enero de 2007 a diciembre de 2013. Material y método: estudio transversal, observacional y retrospectivo efectuado con pacientes que acudieron al servicio de Alergia e Inmunología Clínica del Hospital de Especialidades Dr. Bernardo Sepúlveda del Centro Médico Nacional Siglo XXI de la Ciudad de México, de 2007 a 2013, con diagnóstico de rinitis, asma y conjuntivitis alérgica. Analizamos los resultados de las pruebas cutáneas para pólenes de árboles, gramíneas y malezas de los pacientes. Los resultados se analizaron mediante estadística descriptiva. Resultados: se incluyeron 672 pacientes, 70% hombres, la edad promedio fue de 34 ± 16 años. En relación con su ocupación 31% eran estudiantes, 48% trabajadores y 21% amas de casa. El 53% tenía rinitis alérgica, 47% asma y 40.5% tenía ambos padecimientos. Se encontró prevalencia de sensibilización a malezas de 56%, a árboles de 33% y a gramíneas de 11%. Conclusiones: la sensibilización a malezas constituye en México la primera causa de polinosis respiratoria de la zona sur del Distrito Federal, el polen del amaranto fue el más prevalente en esta zona. La sensibilización a los árboles es la segunda causa de polinosis, con predominio de las familias Betulaceae, Fagaceae y Oleacea. La sensibilización a gramíneas constituye la tercera causa de polinosis respiratoria. Las más frecuentes son la familia Pooideae (Lolium perenne) y la familia Chloroideae (Cynodon dactylon).

  2. Multidrug resistance in Escherichia coli strains isolated from infections in dogs and cats in Poland (2007-2013).

    PubMed

    Rzewuska, Magdalena; Czopowicz, Michał; Kizerwetter-Świda, Magdalena; Chrobak, Dorota; Błaszczak, Borys; Binek, Marian

    2015-01-01

    The antimicrobial susceptibility of Escherichia coli isolates associated with various types of infections in dogs and cats was determined. The studied isolates were most frequently susceptible to fluoroquinolones and the extended-spectrum cephalosporins (ESCs), antimicrobials commonly used in treatment of infections in companion animals. However, an increase in the percentage of strains resistant to β-lactam antibiotics including ESCs was noted between January 2007 and December 2013. The frequency of multidrug-resistant (MDR) E. coli isolation (66.8% of isolates) is alarming. Moreover, the statistically significant increase of the percentage of MDR isolates was observed during the study period. No difference in the prevalence of multidrug resistance was found between bacteria causing intestinal and extraintestinal infections and between canine and feline isolates. Nonhemolytic E. coli isolates were MDR more often than hemolytic ones. Our study showed the companion animals in Poland as an important reservoir of MDR bacteria. These results indicate that continuous monitoring of canine and feline E. coli antimicrobial susceptibility is required. Furthermore, introduction and application of recommendations for appropriate use of antimicrobials in small animal practice should be essential to minimize the emergence of multidrug resistance among E. coli in companion animals.

  3. Inclusion of patient-reported outcome measures in registered clinical trials: Evidence from ClinicalTrials.gov (2007-2013).

    PubMed

    Vodicka, E; Kim, K; Devine, E B; Gnanasakthy, A; Scoggins, J F; Patrick, D L

    2015-07-01

    Patient reported outcomes (PROs) have gained a prominent place in clinical research. Previous estimates suggest that PRO measures are used in 14% of clinical trials. Online registries, such as ClinicalTrials.gov, may be useful in evaluating extent of PRO use. To estimate the proportion of clinical trials using at least one PRO measure and to examine associations between trial characteristics and use of PRO measures. A copy of the ClinicalTrials.gov database was made, containing all data from November 2007 to December 2013. Content was searched for use of PRO measures. Multivariable logistic regression was used to investigate possible associations between trial-level characteristics and use of PRO measures. Of 96,736 registered trials, 26,337 (27%) were identified as using one or more PRO measures. Among oncology trials, 29% (3947/13,584) were identified as using a PRO measure, compared to 27% (22,390/83,152) of non-oncology trials. A greater proportion of trials using PRO measures were more likely to be sponsored by university/research organizations (29%) or the US government (33%), compared to industry (22%); Phase III (35%); non-randomized (32%); and evaluating devices (30%), procedures (31%) or behaviors (50%), compared to drugs (24%). Fewer were FDA-regulated (23%). Evidence suggests that between 2007 and 2013, there has been an increase in the number of trials that use a PRO measure, particularly in oncology trials. With initiatives such as the Patient-Focused Drug Development and FDA PRO Guidance, the trend in the use of PRO measures in clinical research will likely increase further. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. Antenatal care and pregnancy outcomes in a safe motherhood health voucher system in rural Kenya, 2007-2013.

    PubMed

    Kihara, A-B; Harries, A D; Bissell, K; Kizito, W; Van Den Berg, R; Mueke, S; Mwangi, A; Sitene, J C; Gathara, D; Kosgei, R J; Kiarie, J; Gichangi, P

    2015-03-21

    Contexte : Une structure de santé privée rurale, le Ruby Medical Centre (RMC), participant à un système de bons de traitement de Maternité sans risques destiné à des femmes pauvres du conté de Kiambu au Kenya.Objectifs : Entre 2007 et 2013, déterminer 1) le nombre de femmes qui ont accouché au RMC, leurs caractéristiques et le devenir de leur grossesse, et 2) le nombre ne bénéficiant que d’un paquet de soins anténataux (ANC) incomplets et les facteurs associés.Schéma : Etude rétrospective transversale basée sur les données recueillies en routine dans les programmes.Résultats : Au cours de la période d’étude, 2635 femmes ont accouché au RMC : 50% étaient âgées de 16 à 24 ans, 60% avaient été transférées d’autres structures et 59% avaient débuté les ANC au cours du 3(e) trimestre. De ces 2635 femmes, 1793 (68%) avaient un paquet d’ANC incomplet : 347 (13%) ont manqué les principaux tests sanguins, 312 (12%) n’ont pas eu de vaccination anti-tétanique et 1672 (65%) ont eu moins de quatre consultations. Un démarrage tardif et des ANC débutés ailleurs étaient associés à un paquet d’ANC incomplet. Un décès lié à la grossesse est survenu et le taux de mortinatalité a été de 10/1000 naissances.Conclusion : Cette première évaluation du système de bons de traitement dans les zones rurales du Kenya a mis en évidence des problèmes de qualité des ANC. En dépit de l’évolution favorable des grossesses, il est nécessaire d’accroitre les efforts pour faire venir les femmes enceintes plus tôt, offrir des ANC complets et un suivi plus cohérent et précis des indicateurs et des interventions de santé reproductive.

  5. Distribution of Spotted Fever Group Rickettsiae in Hard Ticks (Ixodida: Ixodidae) from Panamanian Urban and Rural Environments (2007-2013).

    PubMed

    Bermúdez, Sergio E; Castro, Angélica M; Trejos, Diomedes; García, Gleydis G; Gabster, Amanda; Miranda, Roberto J; Zaldívar, Yamitzel; Paternina, Luis E

    2016-06-01

    Tick-borne rickettsiosis is an important emerging disease in Panama; to date, there have been 12 confirmed cases, including eight fatalities. To evaluate the distribution of rickettsiae in Panamanian ticks, we collected questing and on-host ticks in urban and rural towns in elevations varying between 0 and 2300 m. A total of 63 sites (13 urban and 50 rural towns) were used to develop models of spatial distributions. We found the following tick species: Rhipicephalus sanguineus s.l. (present in 54 of 63 towns and cities), Amblyomma mixtum (45/63), Dermacentor nitens (40/63), A. ovale (37/63), Rhipicephalus microplus (33/63), A. oblongoguttatum (33/63), Ixodes affinis (3/63), and Ixodes boliviensis (2/63). Rhipicephalus sanguineus s.l. was present in urban and rural towns, and other species were present only in rural towns. DNA was extracted from 408 R. sanguineus s.l., 387 A. mixtum, 103 A. ovale, and 11 A. oblongoguttatum and later tested for rickettsiae genes using PCR. Rickettsia DNA was detected in ticks from 21 of 63 localities. Rickettsia rickettsii was detected in five A. mixtum (1.29%), and Candidatus "Rickettsia amblyommii" was found in 138 A. mixtum (35%), 14 R. sanguineus (3.4%), and one A. ovale (0.9%). These results suggest that much of rural Panama is suitable for the expansion of tick populations and could favor the appearance of new tick-borne rickettsiosis outbreaks.

  6. Vital Signs: Improvements in Maternity Care Policies and Practices That Support Breastfeeding - United States, 2007-2013.

    PubMed

    Perrine, Cria G; Galuska, Deborah A; Dohack, Jaime L; Shealy, Katherine R; Murphy, Paulette E; Grummer-Strawn, Laurence M; Scanlon, Kelley S

    2015-10-09

    Although 80% of U.S. mothers begin breastfeeding their infants, many do not continue breastfeeding as long as they would like to. Experiences during the birth hospitalization affect a mother's ability to establish and maintain breastfeeding. The Baby-Friendly Hospital Initiative is a global program launched by the World Health Organization and the United Nations Children's Fund, and has at its core the Ten Steps to Successful Breastfeeding (Ten Steps), which describe evidence-based hospital policies and practices that have been shown to improve breastfeeding outcomes. Since 2007, CDC has conducted the biennial Maternity Practices in Infant Nutrition and Care (mPINC) survey among all birth facilities in all states, the District of Columbia, and territories. CDC analyzed data from 2007 (baseline), 2009, 2011, and 2013 to describe trends in the prevalence of facilities using maternity care policies and practices that are consistent with the Ten Steps to Successful Breastfeeding. The percentage of hospitals that reported providing prenatal breastfeeding education (range = 91.1%-92.8%) and teaching mothers breastfeeding techniques (range = 87.8%-92.2%) was high at baseline and across all survey years. Implementation of the other eight steps was lower at baseline. From 2007 to 2013, six of these steps increased by 10-21 percentage points, although limiting non-breast milk feeding of breastfed infants and fostering post-discharge support only increased by 5-6 percentage points. Nationally, hospitals implementing more than half of the Ten Steps increased from 28.7% in 2007 to 53.9% in 2013. Maternity care policies and practices supportive of breastfeeding are improving nationally; however, more work is needed to ensure all women receive optimal breastfeeding support during the birth hospitalization. Because of the documented benefits of breastfeeding to both mothers and children, and because experiences in the first hours and days after birth help determine later breastfeeding outcomes, improved hospital policies and practices could increase rates of breastfeeding nationwide, contributing to improved child health.

  7. Prevalence of sleep duration on an average school night among 4 nationally representative successive samples of American high school students, 2007-2013.

    PubMed

    Basch, Charles E; Basch, Corey H; Ruggles, Kelly V; Rajan, Sonali

    2014-12-11

    Consistency, quality, and duration of sleep are important determinants of health. We describe sleep patterns among demographically defined subgroups from the Youth Risk Behavior Surveillance System reported in 4 successive biennial representative samples of American high school students (2007 to 2013). Across the 4 waves of data collection, 6.2% to 7.7% of females and 8.0% to 9.4% of males reported obtaining 9 or more hours of sleep. Insufficient duration of sleep is pervasive among American high school students. Despite substantive public health implications, intervention research on this topic has received little attention.

  8. Trends in reports of driving following illicit drug consumption among regular drug users in Australia, 2007-2013: Has random roadside drug testing had a deterrent effect?

    PubMed

    Horyniak, Danielle; Dietze, Paul; Lenton, Simon; Alati, Rosa; Bruno, Raimondo; Matthews, Allison; Breen, Courtney; Burns, Lucy

    2017-07-01

    Driving following illicit drug consumption ('drug-driving') is a potential road safety risk. Roadside drug testing (RDT) is conducted across Australia with the dual aims of prosecuting drivers with drugs in their system and deterring drug-driving. We examined trends over time in self-reported past six-month drug-driving among sentinel samples of regular drug users and assessed the impact of experiences of RDT on drug-driving among these participants. Data from 1913 people who inject drugs (PWID) and 3140 regular psychostimulant users (RPU) who were first-time participants in a series of repeat cross-sectional sentinel studies conducted in Australian capital cities from 2007 to 2013 and reported driving in the past six months were analysed. Trends over time were assessed using the χ(2) test for trend. Multivariable logistic regressions assessed the relationship between experiences of RDT and recent drug-driving, adjusting for survey year, jurisdiction of residence and socio-demographic and drug use characteristics. The percentage of participants reporting recent (past six months) drug-driving decreased significantly over time among both samples (PWID: 83% [2007] vs. 74% [2013], p<0.001; RPU: 72% vs. 56%, p<0.001), but drug-driving remained prevalent. Lifetime experience of RDT increased significantly over time (PWID: 6% [2007] vs. 32% [2013], p<0.001; RPU: 2% vs. 11%, p<0.001). There were no significant associations between experiencing RDT and drug-driving among either PWID or RPU. Although there is some evidence that drug-driving among key risk groups of regular drug users is declining in Australia, possibly reflecting a general deterrent effect of RDT, experiencing RDT appears to have no specific deterrent effect on drug-driving. Further intervention, with a particular focus on changing attitudes towards drug-driving, may be needed to further reduce this practice among these groups. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Suicidal ideation and associated factors among students aged 13-15 years in Association of Southeast Asian Nations (ASEAN) member states, 2007-2013.

    PubMed

    Peltzer, Karl; Pengpid, Supa

    2017-09-01

    The aim of this study was to assess suicidal ideation and associated factors in school-going adolescents in the Association of Southeast Asian Nations (ASEAN) member states. The analysis included 30,284 school children aged 13-15 years from seven ASEAN countries that participated in the cross-sectional global school-based student health survey (GSHS) between 2007 and 2013. The overall prevalence of suicidal ideation in the past 12 months across seven ASEAN countries was 12.3%, significantly higher in girls (15.1%) than boys (9.3%). Among seven ASEAN countries with the highest prevalence of suicidal ideation was in the Philippines (17.0%) and Vietnam (16.9%) and the lowest in Myanmar (1.1%) and Indonesia (4.2%). In multivariable logistic regression analysis, female gender, older age (14 or 15 years), living in a lower middle income country, having no friends, loneliness, bullying victimisation, having been in a physical fight in the past 12 months, lack of parental or guardian support, tobacco use and having a history of ever got drunk were associated with suicidal ideation. Different rates of suicidal ideation were observed in ASEAN member states. Several risk factors for suicidal ideation were identified which can help guide preventive efforts.

  10. Trends in use of marijuana and attitudes toward marijuana among youth before and after decriminalization: the case of California 2007-2013.

    PubMed

    Miech, Richard A; Johnston, Lloyd; O'Malley, Patrick M; Bachman, Jerald G; Schulenberg, John; Patrick, Megan E

    2015-04-01

    This analysis examines decriminalization as a risk factor for future increases in youth marijuana acceptance and use. Specifically, we examine marijuana-related behaviors and attitudes of 8th, 10th, and 12th graders in California as compared to other U.S. states during the years before and after California passed legislation in 2010 to decriminalize marijuana. Data come from Monitoring the Future, an annual, nationally representative survey of 8th, 10th, and 12th grade students. In 2012 and afterwards California 12th graders as compared to their peers in other states became (a) 25% more likely to have used marijuana in the past 30 days, (b) 20% less likely to perceive regular marijuana use as a great health risk, (c) 20% less likely to strongly disapprove of regular marijuana use, and (d) about 60% more likely to expect to be using marijuana five years in the future. Analysis of 10th graders raises the possibility that the findings among 12th graders may reflect a cohort effect that was set into place two years earlier. These results provide empirical evidence to support concerns that decriminalization may be a risk factor for future increases in youth marijuana use and acceptance. Copyright © 2015 Elsevier B.V. All rights reserved.

  11. Increasing the number of trained health and safety professionals in agricultural medicine: evaluation of the "building capacity" program, 2007-2013.

    PubMed

    Rudolphi, Josie M; Donham, Kelley J

    2015-01-01

    ABSTRACT The University of Iowa began training health care professionals to care for farmers' occupational health needs since 1974. In order to geographically expand this training to practicing health and safety professionals, the "Building Capacity: A National Resource of Agricultural Medicine Professionals" program was developed and launched in 2006. The model began in 1987 as a program of Iowa's Center for Agricultural Safety and Health. In 2006, with funding from the National Institute for Occupational Safety and Health (NIOSH), Great Plains Center for Agricultural Health (GPCAH), the program was expanded beyond the Iowa borders. The principal component of the program, the 40-hour course, Agricultural Medicine: Occupational and Environmental Health for Rural Health Professionals-the Core Course (AMCC) is now being offered to health and safety professionals in nine states in the United States, in Australia, and a modified version presented in Turkey. An initial paper evaluated the first phase of the program, years 2007-2010. This paper compares the first phase (2007-2010) with the second phase (2011-2013), which has involved over 500 health and safety professionals. This paper also describes evaluation of the course and changes resulting from the evaluation. Finally, this paper describes best practices for operating this program and makes recommendations for future courses, as well as other trainings within the field.

  12. Observations of open-ocean deep convection in the northwestern Mediterranean Sea: Seasonal and interannual variability of mixing and deep water masses for the 2007-2013 Period

    NASA Astrophysics Data System (ADS)

    Houpert, L.; Durrieu de Madron, X.; Testor, P.; Bosse, A.; D'Ortenzio, F.; Bouin, M. N.; Dausse, D.; Le Goff, H.; Kunesch, S.; Labaste, M.; Coppola, L.; Mortier, L.; Raimbault, P.

    2016-11-01

    We present here a unique oceanographic and meteorological data set focus on the deep convection processes. Our results are essentially based on in situ data (mooring, research vessel, glider, and profiling float) collected from a multiplatform and integrated monitoring system (MOOSE: Mediterranean Ocean Observing System on Environment), which monitored continuously the northwestern Mediterranean Sea since 2007, and in particular high-frequency potential temperature, salinity, and current measurements from the mooring LION located within the convection region. From 2009 to 2013, the mixed layer depth reaches the seabed, at a depth of 2330m, in February. Then, the violent vertical mixing of the whole water column lasts between 9 and 12 days setting up the characteristics of the newly formed deep water. Each deep convection winter formed a new warmer and saltier "vintage" of deep water. These sudden inputs of salt and heat in the deep ocean are responsible for trends in salinity (3.3 ± 0.2 × 10-3/yr) and potential temperature (3.2 ± 0.5 × 10-3 C/yr) observed from 2009 to 2013 for the 600-2300 m layer. For the first time, the overlapping of the three "phases" of deep convection can be observed, with secondary vertical mixing events (2-4 days) after the beginning of the restratification phase, and the restratification/spreading phase still active at the beginning of the following deep convection event.

  13. Characterization of very-long-period seismicity accompanying summit activity at Kīlauea Volcano, Hawai'i: 2007-2013

    USGS Publications Warehouse

    Dawson, Phillip; Chouet, Bernard

    2014-01-01

    Eruptive activity returned to the summit region of Kīlauea Volcano, Hawai'i with the formation of the “Overlook crater” within the Halema'uma'u Crater in March 2008. The new crater continued to grow through episodic collapse of the crater walls and as of late 2013 had grown into an approximately elliptical opening with dimensions of ~ 160 × 215 m extending to a depth of ~ 200 m. Occasional weak explosive events and a persistent gas plume continued to occur through 2013. Lava was first observed in the new crater in September 2008, and through 2009 the lava level remained deep in the crater and was only occasionally observed. Since early 2010 a lava lake with fluctuating level within the Overlook crater has been nearly continuously present, and has reached to within 22 m of the Overlook crater rim. Volcanic activity at Kīlauea Volcano is episodic at all time scales and the characterization of very-long-period seismicity in the band 2–100 s for the years 2007–2013 illuminates a portion of this broad spectrum of volcanic behavior. Three types of very-long-period events have been observed over this time and each is associated with distinct processes. Type 1 events are associated with vigorous degassing and occurred primarily between 2007 and 2009. Type 2 events are associated with rockfalls onto the lava lake and occurred primarily after early 2010. Both of these event types are induced by pressure and momentum changes at the top of the magma column that are transmitted downward to a source centroid ~ 1 km below the northeast corner of the Halema'uma'u Crater where the energy couples to the solid Earth at a geometrical discontinuity in the underlying dike system. Type 3 events are not related to surficial phenomena but are associated with transients in mass transfer that occur within the dike system. Very-long-period tremor has also accompanied the return of eruptive activity, with increasing amplitude associated with hours- to months-long changes in gas emission rates and summit deformation.

  14. Trends in Use of Seclusion and Restraint in Response to Injurious Assault in Psychiatric Units in U.S. Hospitals, 2007-2013.

    PubMed

    Staggs, Vincent S

    2015-12-01

    This study assessed trends in use of seclusion and restraint in response to injurious assault, including trends in percentage of assaults involving seclusion or restraint; average duration of seclusion; average duration of restraint using devices and holds (physical restraint); and percentages of restraint episodes involving devices, medication, and holds. Monthly administrative data from 2007 to 2013 for 438 adult psychiatric units in 317 U.S. hospitals were aggregated to compute annual measures. Time trends were assessed with nonparametric tests. There was little evidence suggesting a decline in the frequency with which seclusion and restraint are used, but there were decreasing trends in average duration of physical restraint and percentage of restraint episodes involving devices. Efforts to curb seclusion and restraint have apparently been successful in reducing use of devices in restraint and shortening restraint duration. There may be room for improvement in reducing duration of seclusion.

  15. Screening, early detection, education, and trends for melanoma: current status (2007-2013) and future directions: Part II. Screening, education, and future directions.

    PubMed

    Mayer, Jonathan E; Swetter, Susan M; Fu, Teresa; Geller, Alan C

    2014-10-01

    New evidence has accumulated over the past several years that supports improved melanoma outcomes associated with both clinician and patient screening. Population-based and workplace studies conducted in Australia and the Unites States, respectively, have shown decreases in the incidence of thick melanoma and overall melanoma mortality, and a year-long statewide screening program in Germany has shown a nearly 50% reduction in mortality 5 years after the screening ended. Current melanoma screening guidelines in the United States are inconsistent among various organizations, and therefore rates of both physician and patient skin examinations are low. As policymaking organizations update national screening recommendations in the United States, the latest research reviewed in part II of this continuing medical education article should be considered to establish the most effective recommendations. Patient and provider education will be necessary to ensure that appropriate patients receive recommended screening.

  16. Screening, early detection, education, and trends for melanoma: current status (2007-2013) and future directions: Part I. Epidemiology, high-risk groups, clinical strategies, and diagnostic technology.

    PubMed

    Mayer, Jonathan E; Swetter, Susan M; Fu, Teresa; Geller, Alan C

    2014-10-01

    While most cancers have shown both decreased incidence and mortality over the past several decades, the incidence of melanoma has continued to grow, and mortality has only recently stabilized in the United States and in many other countries. Certain populations, such as men >60 years of age and lower socioeconomic status groups, face a greater burden from disease. For any given stage and across all ages, men have shown worse melanoma survival than women, and low socioeconomic status groups have increased levels of mortality. Novel risk factors can help identify populations at greatest risk for melanoma and can aid in targeted early detection. Risk assessment tools have been created to identify high-risk patients based on various factors, and these tools can reduce the number of patients needed to screen for melanoma detection. Diagnostic techniques, such as dermatoscopy and total body photography, and new technologies, such as multispectral imaging, may increase the accuracy and reliability of early melanoma detection.

  17. [First results of participation of the Czech Republic in the 7th Framework Programme, priority Health, in years 2007-2013].

    PubMed

    Kinkorová, Judita

    2013-01-01

    European Commission has announced the first preliminary results of participation in the 7th Framework Programme (FP7), priority Health. The overview presents the basic statistics regarding the participation of the Czech teams, universities, institutions, and small and medium size enterprises (SMEs) in FP7 projects. The aim of the article is to present the basic data on the projects with the Czech participation, the EU financial contribution for Czech teams and the main research topics.

  18. Human biomonitoring reference values for metals and trace elements in blood and urine derived from the Canadian Health Measures Survey 2007-2013.

    PubMed

    Saravanabhavan, Gurusankar; Werry, Kate; Walker, Mike; Haines, Douglas; Malowany, Morie; Khoury, Cheryl

    2017-03-01

    Human biomonitoring reference values are statistical estimates that indicate the upper margin of background exposure to a given chemical at a given time. Nationally representative human biomonitoring data on 176 chemicals, including several metals and trace elements, are available in Canada from 2007 to 2013 through the Canadian Health Measures Survey (CHMS). In this work, we used a systematic approach based on the reference interval concept proposed by the International Federation of Clinical Chemistry and Laboratory Medicine and the International Union of Pure and Applied Chemistry to derive reference values (RV95s) for metals and trace elements. These RV95s were derived for blood and urine matrices in the general Canadian population based on the latest biomonitoring data from the CHMS. Biomarkers were chosen based on specific selection criteria, including widespread detection in Canadians (≥66% detection rate). Reference populations were created for each biomarker by applying appropriate exclusion criteria. Age and sex were evaluated as possible partitioning criteria and separate RV95s were derived for the sub-populations in cases where partitioning was deemed necessary. The RV95s for metals and trace elements in blood ranged from 0.18μg/L for cadmium in young children aged 3-5 years to 7900μg/L for zinc in males aged 20-79 years. In the case of urinary biomarkers, the RV95s ranged from 0.17μg/L for antimony in the total population aged 3-79 years to 1400mg/L for fluoride in adults aged 20-79 years. These RV95s represent the first set of reference values for metals and trace elements in the general Canadian population. We compare the RV95s from other countries where available and discuss factors that could influence such comparisons. Copyright © 2016 The Authors. Published by Elsevier GmbH.. All rights reserved.

  19. Door to Intravenous Tissue Plasminogen Activator Time and Hospital Length of Stay in Acute Ischemic Stroke Patients, Georgia, 2007-2013.

    PubMed

    Ido, Moges Seyoum; Okosun, Ike S; Bayakly, Rana; Clarkson, Lydia; Lugtu, James; Floyd, Sanita; Krompf, Kerrie; Frankel, Michael

    2016-04-01

    Ischemic stroke patients benefit most from intravenous thrombolysis when they receive the treatment as quickly as possible after symptom onset. Hospitals participating in the Georgia Coverdell Acute Stroke Registry reduced the time from patient arrival to administration of intravenous tissue plasminogen activator. This study evaluates the benefit of reducing door-to-treatment (DTT) time as measured by hospital length of stay (LOS). Data from 3154 ischemic stroke patients treated with intravenous thrombolysis from 2007 to 2013 were analyzed. The impact of door-to-treatment time on patients' length of hospital stay, discharge disposition, ambulatory status at discharge, and bleeding complications was assessed, controlling for patient-, hospital- and event-related characteristics. Patients who received intravenous thrombolysis within 30 minutes of hospital arrival had a 19% shorter (95% confidence interval [CI]: 2%-32%, P value = .04) hospital LOS than those treated for more than 120 minutes after arrival. Patients treated within 60 minutes of arrival were 27% more likely (odds ratio = 1.28, 95% CI: 1.06-1.56, P = .01) to have a better discharge disposition than patients treated after 60 minutes of arrival while having a similar rate of bleeding complications. Shortening the door-to-treatment time is associated with a decrease in patient LOS and better patient outcomes. Hospitals should be encouraged to measure, monitor, and reduce DTT time progressively for a better patient outcome. Copyright © 2016 National Stroke Association. Published by Elsevier Inc. All rights reserved.

  20. Effects of Antiretroviral Therapy on the Survival of Human Immunodeficiency Virus-positive Adult Patients in Andhra Pradesh, India: A Retrospective Cohort Study, 2007-2013

    PubMed Central

    Chaturvedi, Himanshu; Jayaseelan, Lakshmanan; Harvey, Pauline; Seguy, Nicole; Chavan, Laxmikant; Raj, Pinnamaneni; Pandey, Arvind

    2016-01-01

    Objectives The survival outcomes of antiretroviral treatment (ART) programs have not been systematically evaluated at the state level in India. This retrospective study assessed the survival rates and factors associated with survival among adult human immunodeficiency virus (HIV)-infected patients in Andhra Pradesh, India. Methods The present study used data from 139 679 HIV patients aged ≥15 years on ART who were registered from 2007 to 2011 and were followed up through December 2013. The primary end point was death of the patient. Mortality densities (per 1000 person-years) were calculated. Kaplan-Meier and Cox-regression models were used to estimate survival and explore the factors associated with survival. Results The overall median follow-up time was 16.0 months (2.0 months for the deceased and 14.0 months for those lost to follow-up). Approximately 13.2% of those newly initiated on ART died during follow-up. Of those deaths, 56% occurred in the first three months. The crude mortality rate was 80.9 per 1000 person-years at risk. The CD4 count (adjusted hazard ratio [aHR],4.88; 95% confidence interval [CI], 4.36 to 5.46 for <100 cells/mm3 vs. >350 cells/mm3), functional status (aHR, 3.05; 95% CI, 2.82 to 3.30 for bedridden vs. normal), and body weight (aHR, 3.69; 95% CI, 3.42 to 3.97 for <45 kg vs. >60 kg) were strongly associated with the survival of HIV patients. Conclusions The study findings revealed that high mortality was observed within the first three months of ART initiation. Patients with poor baseline clinical characteristics had a higher risk of mortality. Expanded testing and counseling should be encouraged, with the goal of ensuring early enrollment into the program followed by the initiation of ART in HIV-infected patients. PMID:27951632

  1. Characteristics of bone fractures and usefulness of micro-computed tomography for fracture detection in rabbits: 210 cases (2007-2013).

    PubMed

    Sasai, Hiroshi; Fujita, Daisuke; Tagami, Yukari; Seto, Eiko; Denda, Yuki; Hamakita, Hideaki; Ichihashi, Tomonori; Okamura, Kensaku; Furuya, Masaru; Tani, Hiroyuki; Sasai, Kazumi; Yamate, Jyoji

    2015-06-15

    To characterize bone fractures and the usefulness of micro-CT for imaging fractures in pet rabbits. Retrospective case series. 210 client-owned rabbits with bone fractures. Medical records of rabbits evaluated for bone fractures from 2007 through 2013 were examined. Information was collected on signalment and nature of fractures, and radiographic and micro-CT images of fractures were reviewed. Almost half (n = 95 [47.7%]) of fractures were in rabbits < 3 years old. Accidental fall was the most common cause. Vertebral fracture was the most common type of fracture with a nonneoplastic cause (n = 46 [23.2%]) and was most common in the L4-L7 region. The tibia was the most common site for limb fracture among all fractures with a nonneoplastic cause (45 [22.7%]). Twelve (5.7%) fractures had a neoplastic cause, and 7 of these were associated with metastatic uterine adenocarcinoma. Females were significantly more likely to have a fracture caused by neoplasia than were males. Compared with radiography, micro-CT provided more detailed fracture information, particularly for complicated fractures or structures (eg, skull, pelvic, vertebral, and comminuted limb fractures). Findings were useful for understanding the nature of fractures in pet rabbits and supported the use of micro-CT versus radiography for fracture detection and evaluation.

  2. Retrospective analysis of reproductive health indicators in the United Nations High Commissioner for Refugees post-emergency camps 2007-2013.

    PubMed

    Whitmill, Jennifer; Blanton, Curtis; Doraiswamy, Sathyanarayanan; Cornier, Nadine; Schilperood, Marian; Spiegel, Paul; Tomczyk, Barbara

    2016-01-01

    The United Nations Refugee Agency's Health Information System issues analytical reports on the current camp conditions and trends for priority reproductive health issues. The goal was to assess the status of reproductive health by analyzing seven indicators and comparing them to standards and host country estimates. Data on seven indicators were extracted from the database during a seven-year period (2007 through 2013). A standardized country inclusion criterion was created based on the year of country implementation and the percentage of missing reports per camp and year. The unit of analysis was monthly camp reports by year within a country. To account for the lack of independence of monthly camp reports, the variance was computed using Taylor Series Linearization methods in SAS. Ten of the 23 eligible countries met the inclusion criterion. The mean camp maternal and neonatal mortality rates, except for two country years, were lower than the host country estimates for all countries and years. There was a significant increase in the percent of births attended by a skilled birth attendant (p < 0.0001), and 8 of 10 countries did not meet the standard of 100 % for all reporting years. The percent of births performed by Caesarian section (p < 0.001), were below the recommended minimum standard for nearly half of the countries every year. There was a significant increase in the percent of women screened for syphilis across years (p < 0.0001) and the percent of women who received post HIV exposure prophylaxis (p < 0.0001) and 10 % reached the standard for all reporting years, respectively. Comprehensive, consistent and comparable statistics on reproductive health provides an opportunity to assess progress towards indicator standards. Despite some improvements over time, this analysis confirms that most countries did not meet standards and that there were differences in reproductive health indicators between countries and across years. Consequently, the HIS periodic monitoring of key reproductive health indicators at the camp level should continue. Data should be used to improve intervention strategies.

  3. Leisure Time Physical Inactivity and Sedentary Behaviour and Lifestyle Correlates among Students Aged 13-15 in the Association of Southeast Asian Nations (ASEAN) Member States, 2007-2013.

    PubMed

    Peltzer, Karl; Pengpid, Supa

    2016-02-15

    The aim of this study was to examine the relationship between self-reported leisure time physical inactivity frequency and sedentary behaviour and lifestyle correlates among school children in the Association of Southeast Asian Nations (ASEAN) region. The analysis included 30,284 school children aged 13-15 years from seven ASEAN countries that participated in the Global School-based Student Health Survey (GSHS) between 2007 and 2013. The measure asked about overall physical activity, walking or biking to school, and on time spent sitting. Overall, the prevalence of physical inactivity was 80.4%, ranging from 74.8% in Myanmar to 90.7% in Cambodia and sedentary behaviour 33.0%, ranging from 10.5% in Cambodia and Myanmar to 42.7% in Malaysia. In multivariate logistic regression, not walking or biking to school, not attending physical education classes, inadequate vegetable consumption and lack of protective factors (peer and parental or guardian support) were associated with physical inactivity, and older age (14 and 15 years old), coming from an upper middle income country, being overweight or obese, attending physical education classes, alcohol use, loneliness, peer support and lack of parental or guardian supervision were associated with sedentary behaviour. In boys, lower socioeconomic status (in the form of having experienced hunger) and coming from a low income or lower middle income country were additionally associated with physical inactivity, and in girls, higher socioeconomic status, not walking or biking to school and being bullied were additionally associated with sedentary behaviour. In conclusion, a very high prevalence of leisure physical inactivity and sedentary behaviour among school going adolescents in ASEAN was found and several factors identified that may inform physical activity promotion programmes in school-going adolescents in ASEAN.

  4. 78 FR 64189 - Drawbridge Operation Regulation; Raccoon Creek, Bridgeport, NJ

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-28

    ... mile marker 1.8 in Bridgeport, NJ. Bridge tender logs from 2007-2013 indicates that the majority of the... logs dating back to 2007 to illustrate the marine traffic patterns on Raccoon Creek. Based on the... advanced notice. Based on the average logged openings between 2007-2013 during the months of March,...

  5. 78 FR 64186 - Drawbridge Operation Regulation; Mantua Creek, Paulsboro, NJ

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-28

    ... Mantua Creek, mile marker 1.7, at Paulsboro, NJ. Bridge tender logs from 2007- 2013 indicates that the..., across Mantua Creek at Paulsboro. NJDOT provided the Coast Guard with the bridge tender logs dating back... provide 4 hours advanced notice. Based on the average logged openings between 2007-2013 during the...

  6. Cyberbullying: A Review of the Literature

    ERIC Educational Resources Information Center

    Notar, Charles E.; Padgett, Sharon; Roden, Jessica

    2013-01-01

    The article is a literature review on cyberbullying from 2007-2013. Topics covered in the review have been categorized starting with definition of cyberbullying; roles of persons involved and statistics of who is being targeted; reasons for cyberbullying; differences between traditional bullying and cyberbullying; and gender comparisons related to…

  7. Review of Study Programme Renewal in Lithuania: Planning Students' Independent Work

    ERIC Educational Resources Information Center

    Zibeniene, Gintaute

    2013-01-01

    The article introduces external quality assessment results of first cycle and second cycle study programmes renewed under the Human Resources Development Action Programme 2007-2013 priority direction 2 "Lifelong Learning" (hereinafter the "Programme") through the aspect of planning students' independent work. Problems faced…

  8. Teaching Excellence Initiatives: Modalities and Operational Factors

    ERIC Educational Resources Information Center

    Land, Ray; Gordon, George

    2015-01-01

    Teaching excellence is at the centre of national and international higher education policy. The Higher Education Academy (HEA) is a part of the debate to develop a shared understanding of what constitutes teaching excellence and has published research including "Considering Teaching Excellence in Higher Education: 2007-2013" by Dr Vicky…

  9. Cattle grazing and vegetation succession on burned sagebrush steppe

    USDA-ARS?s Scientific Manuscript database

    There is limited information on the effects of cattle grazing to longer-term plant community composition and productivity following fire in big sagebrush steppe. This study evaluated vegetation response to cattle grazing over seven years (2007-2013) on burned Wyoming big sagebrush (Artemisia triden...

  10. VizieR Online Data Catalog: Lynx-Cancer void sample galaxies HI data (Pustilnik+, 2016)

    NASA Astrophysics Data System (ADS)

    Pustilnik, S. A.; Martin, J.-M.

    2017-03-01

    The HI observations were made during the period 2007-2013 with the Nancay Radio Telescope (NRT). In Table A.1 we present the main parameters taken from NED1, SDSS2 or from the literature for all observed 45 void galaxies. ************************************************************************** * * * Sorry, but the author(s) never supplied the fits spectra as * * announced in the paper * * * ************************************************************************** (3 data files).

  11. Farmers' Knowledge Attributes Contribute to Attaining Higher Farm Technical Efficiency: A Transition Economy Case

    ERIC Educational Resources Information Center

    Manevska-Tasevska, Gordana

    2013-01-01

    Purpose: This study sought to explore how farmers' knowledge attributes influence the technical efficiency of their farms. In addition, farm efficiency was compared to the actual Macedonian Rural Development Programme (RDP) (2007-2013) and instruments considered to improve Macedonian education potential were evaluated. Design/methodology/approach:…

  12. Farmers' Knowledge Attributes Contribute to Attaining Higher Farm Technical Efficiency: A Transition Economy Case

    ERIC Educational Resources Information Center

    Manevska-Tasevska, Gordana

    2013-01-01

    Purpose: This study sought to explore how farmers' knowledge attributes influence the technical efficiency of their farms. In addition, farm efficiency was compared to the actual Macedonian Rural Development Programme (RDP) (2007-2013) and instruments considered to improve Macedonian education potential were evaluated. Design/methodology/approach:…

  13. Teaching Excellence Initiatives: Modalities and Operational Factors

    ERIC Educational Resources Information Center

    Land, Ray; Gordon, George

    2015-01-01

    Teaching excellence is at the centre of national and international higher education policy. The Higher Education Academy (HEA) is a part of the debate to develop a shared understanding of what constitutes teaching excellence and has published research including "Considering Teaching Excellence in Higher Education: 2007-2013" by Dr Vicky…

  14. Data set: weather, snow, and streamflow data from four western juniper-dominated experimental catchments in southwestern Idaho, USA

    USDA-ARS?s Scientific Manuscript database

    Data set on weather, snow, stream, topographic, and vegetation data from the South Mountain Experimental Catchments from water years 2007-2013 (10-1-2007 to 9-30-2013). The data provide detailed information on the weather and hydrologic response for four highly instrumented catchments in the late st...

  15. New records of bee flies (Diptera, Bombyliidae) from Cuatro Ciénegas, Coahuila, Mexico.

    PubMed

    Avalos-Hernández, Omar; Kits, Joel; Trujano-Ortega, Marysol; García-Vázquez, Uri Omar; Cano-Santana, Zenón

    2014-01-01

    Forty one new records of species of Bombyliidae are reported for Coahuila in northeastern Mexico. Nine of these species are reported for the first time for the country. The specimens were collected in the Cuatro Ciénegas Basin and Sierra La Madera mountains during 2007-2013. The modified distributions of species are discussed. The gaps in the distribution of many species suggest an undersampling of this group of insects in the north of Mexico.

  16. 2013 US State of Cybercrime Survey: How Bad is the Insider Threat?

    DTIC Science & Technology

    2013-08-01

    Insiders 51% Unknown 24 % © 2007-2013 Carnegie Mellon University 2013 US State of Cybercrime Survey How Bad is the Insider Threat? Report...TYPE 3. DATES COVERED 00-00-2013 to 00-00-2013 4. TITLE AND SUBTITLE 2013 US State of Cybercrime Survey: How Bad is the Insider Threat? 5a...State of Cybercrime Survey -1 CSO Magazine, USSS, CERT & Deloitte 501 respondents 34% of organizations have more than 5000 employees 40% of

  17. Incidence of narcolepsy before and after MF59-adjuvanted influenza A(H1N1)pdm09 vaccination in South Korean soldiers.

    PubMed

    Kim, Woo Jung; Lee, Sang Don; Lee, Eun; Namkoong, Kee; Choe, Kang-Won; Song, Joon Young; Cheong, Hee Jin; Jeong, Hye Won; Heo, Jung Yeon

    2015-09-11

    Previous reports mostly from Europe suggested an association between an occurrence of narcolepsy and an influenza A(H1N1)pdm09 vaccine adjuvanted with AS03 (Pandemrix(®)). During the 2009 H1N1 pandemic vaccination campaign, the Korean military performed a vaccination campaign with one type of influenza vaccine containing MF59-adjuvants. This study was conducted to investigate the background incidence rate of narcolepsy in South Korean soldiers and the association of the MF59-adjuvanted vaccine with the occurrence of narcolepsy in a young adult group. To assess the incidence of narcolepsy, we retrospectively reviewed medical records of suspicious cases of narcolepsy in 2007-2013 in the whole 20 military hospitals of the Korean military. The screened cases were classified according to the Brighton Collaboration case definition of narcolepsy. After obtaining the number of confirmed cases of narcolepsy per 3 months in 2007-2013, we compared the crude incidence rate of narcolepsy before and after the vaccination campaign. We included 218 narcolepsy suspicious cases in the initial review, which were screened by the diagnostic code on the computerized disease registry in 2007-2013. Forty-one cases were finally diagnosed with narcolepsy in 2007-2013 (male sex, 95%; median age, 21 years). The average background incidence rate of narcolepsy in Korean soldiers was 0.91 cases per 100,000 persons per year. During the 9 months before vaccination implementation (April to December 2009), 6 narcolepsy cases occurred, whereas during the next 9 months (January to September 2010) including the 3-month vaccination campaign, 5 cases occurred. The incidence of narcolepsy in South Korean soldiers was not increased after the pandemic vaccination campaign using the MF59-adjuvanted vaccine. Our results suggest that the MF59-adjuvanted H1N1 vaccine did not contribute to the occurrence of narcolepsy in this young adult group. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. [Risk of tuberculosis in healthcare workers: risk assessment and medical surveillance].

    PubMed

    Magrini, Andrea; Coppeta, Luca; Somma, Giuseppina; Neri, Anna; Gentili, Sandro; Fiocco, Giovanni; Pietroiusti, Antonio

    2016-01-01

    Tuberculosis screening is recommended for all health care workers. We evaluated the prevalence of latent tuberculosis infection among 939 hospital workers of Tor Vergata University teaching hospital in Rome, Italy, in the period 2007-2013, by using the QuantiFERON Gold In-Tube (QFT) test. The mean age of subjects tested was 31 years. The prevalence of positive subjects (cut-off 0.35 UI/ml) was 5.5% (46/939) and the mean age of those who tested positive was 39 years. The low rate of positivity may be partly related to the higher reliability of QFT in comparison to tuberculin skin testing.

  19. Variation in relative dust impact charge recollection with antenna to spacecraft potential on STEREO

    NASA Astrophysics Data System (ADS)

    Thayer, Frederick M.; Malaspina, David M.; Collette, Andrew; Sternovsky, Zoltan

    2016-06-01

    High-velocity dust that impacts spacecraft releases charged plasma clouds that can create voltage perturbations that are measured by electric field instrumentation. These voltage perturbations are characterized by a relative maximum and minimum, which correspond to body and antenna charge recollection, respectively. The charge recollected by the antenna relative to the total recollected charge is found to correlate with the potential difference between the spacecraft and the antenna. From data analysis that spanned 2007-2013 on the STEREO-A spacecraft, a positive correlation is found. This relationship will support future dust analysis with electric field instrumentation because it defines one spacecraft property that affects relative charge recollection.

  20. From local development policies to strategic planning-Assessing continuity in institutional coalitions.

    PubMed

    Mazzeo Rinaldi, Francesco

    2016-06-01

    In the last two decades, EU policies have had a fundamental role in orienting regional/local development. The objective of this work is set in this context as it intends to analyze the local development programs activated in Sicily in the last three programming periods. The main aim is to explore whether the EU partnership principle influenced cooperation among local actors, assessing the continuity of local institutional coalition in managing different local development programs within the regional development policy system. We focus, in particular, on Strategic Plans (SP) promoted in Sicily in the transition phase between the 2000-2006 and the 2007-2013 periods.

  1. [Medium-term strategy for the specific management of pneumology hospitals and wards after the decentralization of the sanitary system].

    PubMed

    Muşat, Simona Nicoleta; Ioniţa, Diana; Paceonea, Mirela; Chiriac, Nona Delia; Stoicescu, Ileana Paula; Mihălţan, F D

    2011-01-01

    Identifying and promoting new management techniques for the descentralized pneumology hospitals or wards was one of the most ambitious objectives of the project "Quality in the pneumology medical services through continuous medical education and organizational flexibility", financed by the Human Resourses Development Sectorial Operational Programme 2007-2013 (ID 58451). The "Medium term Strategy on the specific management of the pneumology hospitals or wards after the descentralization of the sanitary system" presented in the article was written by the project's experts and discussed with pneumology managers and local authorities representatives. This Strategy application depends on the colaboration of the pneumology hospitals with professional associations, and local and central authorities.

  2. Effectiveness of Integrated Best Management Practices on Mitigation of Atrazine and Metolachlor in an Agricultural Lake Watershed.

    PubMed

    Lizotte, Richard; Locke, Martin; Bingner, Ronald; Steinriede, R Wade; Smith, Sammie

    2017-04-01

    The study examined the influence of land-use (cropping patterns) and integrated agricultural best management practices (BMPs) on spring herbicide levels in an agricultural watershed. Atrazine and metolachlor were applied for weed control during spring of 1998-2002, 2005, and 2007-2013. Watershed-wide mass of applied herbicides ranged from 12.7 to 209.2 g atrazine and 10.9-302.2 g metolachlor with greatest application during 1998, 2009-2010 (atrazine) and 2007-2013 (metolachlor). Spring herbicide concentrations in Beasley Lake water ranged from below detection to 3.54 μg atrazine/L and 3.01 μg metolachlor/L. Multiple linear regression analyses with cropping patterns, BMPs, rainfall and time as independent variables, showed atrazine applications were associated with increases in cotton acreage and quail buffer, while metolachlor applications increased over time. Multiple linear regressions showed lake atrazine concentrations were associated with conservation tillage, rainfall, and corn, while lake metolachlor concentrations were associated with the cumulative metolachlor application and sediment retention pond installation.

  3. Dimming titan revealed by the Cassini observations.

    PubMed

    Li, Liming

    2015-02-04

    Here we report the temporal variation of Titan's emitted energy with the Cassini/CIRS observations. In the northern hemisphere, the hemispheric-average emitted power decreased from 2007 to 2009 and increased from 2009 to 2012-13, which make the net change insignificant (0.1 ± 0.2%) during the period 2007-2013. The decrease from 2007 to 2009 is mainly due to the cooling around the stratospause, and the increase from 2009 to 2012-13 is probably related to temporal variation of atmospheric temperature around the tropopuase in the northern hemisphere. In the southern hemisphere, the emitted power continuously decreased by 5.0 ± 0.6% from 2.40 ± 0.01 W/m(2) in 2007 to 2.28 ± 0.01 in 2012-13, which is mainly related to Titan's seasonal variation. The asymmetry in the temporal variation between the two hemispheres results in the global-average emitted power decreasing by 2.5 ± 0.6% from 2.41 ± 0.01 W/m(2) in 2007 to 2.35 ± 0.01 W/m(2) in 2012-13. The solar constant at Titan decreased by ~13.0% in the same period 2007-2013, which is much stronger than the temporal variation of emitted power. The measurements of Titan's absorbed solar power are needed to determine the temporal variation of the global energy budget.

  4. Dimming Titan Revealed by the Cassini Observations

    NASA Astrophysics Data System (ADS)

    Li, Liming

    2015-02-01

    Here we report the temporal variation of Titan's emitted energy with the Cassini/CIRS observations. In the northern hemisphere, the hemispheric-average emitted power decreased from 2007 to 2009 and increased from 2009 to 2012-13, which make the net change insignificant (0.1 +/- 0.2%) during the period 2007-2013. The decrease from 2007 to 2009 is mainly due to the cooling around the stratospause, and the increase from 2009 to 2012-13 is probably related to temporal variation of atmospheric temperature around the tropopuase in the northern hemisphere. In the southern hemisphere, the emitted power continuously decreased by 5.0 +/- 0.6% from 2.40 +/- 0.01 W/m2 in 2007 to 2.28 +/- 0.01 in 2012-13, which is mainly related to Titan's seasonal variation. The asymmetry in the temporal variation between the two hemispheres results in the global-average emitted power decreasing by 2.5 +/- 0.6% from 2.41 +/- 0.01 W/m2 in 2007 to 2.35 +/- 0.01 W/m2 in 2012-13. The solar constant at Titan decreased by ~13.0% in the same period 2007-2013, which is much stronger than the temporal variation of emitted power. The measurements of Titan's absorbed solar power are needed to determine the temporal variation of the global energy budget.

  5. Regime shift in Arabian dust activity, triggered by persistent Fertile Crescent drought

    NASA Astrophysics Data System (ADS)

    Notaro, Michael; Yu, Yan; Kalashnikova, Olga V.

    2015-10-01

    The Arabian Peninsula has experienced pronounced interannual to decadal variability in dust activity, including an abrupt regime shift around 2006 from an inactive dust period during 1998-2005 to an active period during 2007-2013. Corresponding in time to the onset of this regime shift, the climate state transitioned into a combined La Niña and negative phase of the Pacific Decadal Oscillation, which incited a hiatus in global warming in the 2000s. Superimposed upon a long-term regional drying trend, synergistic interactions between these teleconnection modes triggered the establishment of a devastating and prolonged drought, which engulfed the Fertile Crescent, namely, Iraq and Syria, and led to crop failure and civil unrest. Dried soils and diminished vegetation cover in the Fertile Crescent, as evident through remotely sensed enhanced vegetation indices, supported greater dust generation and transport to the Arabian Peninsula in 2007-2013, as identified both in increased dust days observed at weather stations and enhanced remotely sensed aerosol optical depth. According to backward trajectory analysis of dust days on the Arabian Peninsula, increased dust lifting and atmospheric dust concentration in the Fertile Crescent during this recent, prolonged drought episode supported a greater frequency of dust events across the peninsula with associated northerly trajectories and led to the dust regime shift. These findings are particularly concerning, considering projections of warming and drying for the eastern Mediterranean region and potential collapse of the Fertile Crescent during this century.

  6. Migration-related tuberculosis: epidemiology and characteristics of tuberculosis cases originating outside the European Union and European Economic Area, 2007 to 2013.

    PubMed

    Ködmön, Csaba; Zucs, Phillip; van der Werf, Marieke J

    2016-01-01

    Migrants arriving from high tuberculosis (TB)-incidence countries may pose a significant challenge to TB control programmes in the host country. TB surveillance data for 2007-2013 submitted to the European Surveillance System were analysed. Notified TB cases were stratified by origin and reporting country. The contribution of migrant TB cases to the TB epidemiology in EU/EEA countries was analysed. Migrant TB cases accounted for 17.4% (n = 92,039) of all TB cases reported in the EU/EEA in 2007-2013, continuously increasing from 13.6% in 2007 to 21.8% in 2013. Of 91,925 migrant cases with known country of origin, 29.3% were from the Eastern Mediterranean, 23.0% from south-east Asia, 21.4% from Africa, 13.4% from the World Health Organization European Region (excluding EU/EEA), and 12.9% from other regions. Of 46,499 migrant cases with known drug-susceptibility test results, 2.9% had multidrug-resistant TB, mainly (51.7%) originating from the European Region. The increasing contribution of TB in migrants from outside the EU/EEA to the TB burden in the EU/EEA is mainly due to a decrease in native TB cases. Especially in countries with a high proportion of TB cases in non-EU/EEA migrants, targeted prevention and control initiatives may be needed to progress towards TB elimination.

  7. The effect of migration within the European Union/European Economic Area on the distribution of tuberculosis, 2007 to 2013.

    PubMed

    Hollo, Vahur; Kotila, Saara Magdalena; Ködmön, Csaba; Zucs, Phillip; van der Werf, Marieke Johanna

    2016-01-01

    Immigration from tuberculosis (TB) high-incidence countries is known to contribute notably to the TB burden in low-incidence countries. However, the effect of migration enabled by the free movement of persons within the European Union (EU)/European Economic Area (EEA) on TB notification has not been analysed. We analysed TB surveillance data from 29 EU/EEA countries submitted for the years 2007-2013 to The European Surveillance System. We used place of birth and nationality as proxy indicators for native, other EU/EEA and non-EU/EEA origin of the TB cases and analysed the characteristics of the subgroups by origin. From 2007-2013, a total of 527,467 TB cases were reported, of which 129,781 (24.6%) were of foreign origin including 12,566 (2.4%) originating from EU/EEA countries other than the reporting country. The countries reporting most TB cases originating from other EU/EEA countries were Germany and Italy, and the largest proportion of TB cases in individuals came from Poland (n=1,562) and Romania (n=6,285). At EU/EEA level only a small proportion of foreign TB cases originated from other EU/EEA countries, however, the uneven distribution of this presumed importation may pose a challenge to TB programmes in some countries.

  8. Mercury in the atmosphere and in rainwater at Cape Point, South Africa

    NASA Astrophysics Data System (ADS)

    Brunke, Ernst-Günther; Walters, Chavon; Mkololo, Thumeka; Martin, Lynwill; Labuschagne, Casper; Silwana, Bongiwe; Slemr, Franz; Weigelt, Andreas; Ebinghaus, Ralf; Somerset, Vernon

    2016-01-01

    Mercury measurements were concurrently made in air (Gaseous Elemental Mercury, i.e. GEM) as well as in precipitation samples (Total mercury, i.e. TotHg) over a seven year period (2007-2013) at Cape Point, South Africa, during the rainy seasons (May-October). Eighty-five rain events, almost exclusively associated with cold fronts, have been identified of which 75% reached the Cape Point observatory directly across the Atlantic Ocean from the south, while 19% moved in to the measuring site via the Cape Town metropolitan region. In statistic terms the GEM, TotHg, CO and 222Rn levels within the urban-marine events do not differ from those seen in the marine rain episodes. Over the 2007-2013 period, the May till Oct averages for GEM ranged from 0.913 ng m-3 to 1.108 ng m-3, while TotHg concentrations ranged from 0.03 to 52.5 ng L-1 (overall average: 9.91 ng L-1). A positive correlation (R2 = 0.49, n = 7) has been found between the average annual (May till October) GEM concentrations in air and TotHg concentration in rainwater suggesting a close relationship between the two species. The wetter years are normally associated with higher GEM and TotHg levels. Both GEM and TotHg annual means correlate positively with total annual (May till October) rain depths. If one or two outlier years are removed from the data set, the R2 values increase from 0.23 to 0.10 for GEM and TotHg to 0.97 (n = 5) and 0.89 (n = 5), respectively. The relationship between annual mean GEM and annual precipitation depth also holds for the period 1996-2004 (R2 = 0.6, n = 8) when GEM was measured manually (low resolution data). A positive correlation was also seen between annual average GEM concentrations and the El Niño Southern Oscillation (ENSO) Index (SOI), for the 1996-2004 period (R2 = 0.7, n = 8). For the 2007-2013 periods this relationship was also positive but less pronounced. The relationship between annual precipitation depth and annual SOI suggests that the inter-annual variations of GEM

  9. Double Current Sheet Instabilities and the Transition to Turbulence.

    NASA Astrophysics Data System (ADS)

    Pucci, F.; Velli, M.; Biferale, L.; Sahoo, G.

    2016-12-01

    The double tearing instability has often been studied as a proxy for the m=1 kink mode in cylindrical plasma. In this paper we describe the results of 3D simulations of an initially periodic double current sheet described by Harris equilibria with a guide field in two cases: 1) zero net helicity and an average magnetic field and 2) a well defined helicity (force free but non constant alpha). We study and contrast the de-stabilization and transition to turbulence for these two cases: we describe spectra, cascades, and possible application to heliospheric phenomena, in particular CME evolution and relaxation. The research leading to these results has received fund- ing from the European Union's Seventh Framework Pro- gramme (FP7/2007-2013) under grant agreement No. 339032

  10. How to Bring a Building Back From Ruins / Jak Wyprowadzić Budynek z Ruiny?

    NASA Astrophysics Data System (ADS)

    Błaszczyński, Tomasz; Sokołowski, Wojciech

    2016-03-01

    This paper is about the renovation of the baroque palace in Żagań. The journey starts at what was once a Medieval castle and finishes in the XIX century at the villa of Żagań Princes. Now the building is a XIX century villa maintained in a baroque style. The castle was built in the Middle Ages by Silesian Piasts and rebuilt three times, first by prince Wallenstein, then by prince Lobkovic, and finally, in the XVIII century, by princess Talleyrand. It remained the property of a French citizen until the 1960s, with its condition slowly decaying. In 1965, it was almost totally destroyed. Then the first renovation and revitalization works were initiated, lasting almost twenty years. The second renovation took place in the years 2007-2013, co-funded by the European Union. However, as a result of some cost cutting, the palace now requires a further, third approach to renovation.

  11. Status of efforts on fundamental and applied studies with tritium at RFNC-VNIIEF

    SciTech Connect

    Yukhimchuk, A.A.; Ilkaev, R.I.

    2015-03-15

    This paper gives an overview of the efforts in the field of fundamental and applied physics with tritium carried out with the participation of RFNC-VNIIEF in 2007-2013. New physical results in the study of muon-catalyzed fusion and neutron-excess nuclei are presented; a project of a new experiment on searching for a magnetic moment of the neutrino using a tritium source and helium detector is discussed. The description of a tritium support test-bed for a plasma focus-type neutron source with intensity of 10{sup 13} s{sup -1} is given. Results of studies in the area of interaction of hydrogen isotopes with structural materials such as nickel, stainless steels, high-strength austenitic alloys and alumina-based ceramics are summarized. (authors)

  12. Beam dynamics in THz dielectric-loaded waveguides for the AXSIS project

    NASA Astrophysics Data System (ADS)

    Vinatier, T.; Assmann, R. W.; Dorda, U.; Lemery, F.; Marchetti, B.

    2017-07-01

    In this paper, we investigate with ASTRA simulations the beam dynamics in dielectric-loaded waveguides driven by THz pulses, used as linac structure for the AXSIS project. We show that the bunch properties at the linac exit are very sensitive to the phase velocity of the THz pulse and are limited by the strong phase slippage of the bunch respective to it. We also show that the bunch properties are optimized when low frequencies (< 300 GHz) are used inside the linac, and that the longitudinal focal point can be put several tens of cm away from the linac exit thanks to ballistic bunching. However, a strong asymmetry in the bunch transverse sizes remains for which a solution is still to be found. Work supported by the European Research Council under the European Union’s Seventh Framework Programme (FP/2007-2013)/ERC Grant Agreement n. 609920.

  13. Beverages Sales in Mexico before and after Implementation of a Sugar Sweetened Beverage Tax.

    PubMed

    Colchero, M A; Guerrero-López, Carlos Manuel; Molina, Mariana; Rivera, Juan Angel

    To estimate changes in sales of sugar sweetened beverages (SSB) and plain water after a 1 peso per liter excise SSB tax was implemented in Mexico in January 2014. We used sales data from the Monthly Surveys of the Manufacturing Industry from January 2007 to December 2015. We estimated Ordinary Least Squares models to assess changes in per capita sales of SSB and plain water adjusting for seasonality and the global indicator of economic activity. We found a decrease of 7.3% in per capita sales of SSB and an increase of 5.2% of per capita sales of plain water in 2014-2015 compared to the pre-tax period (2007-2013). Adjusting for variables that change over time and that are associated with the demand for SSB, we found the tax was associated with a reduction in per capita sales of SSB. The effectiveness of the tax should be evaluated in the medium and long term.

  14. Entry and return times for semi-flows

    NASA Astrophysics Data System (ADS)

    Marklof, Jens

    2017-02-01

    Haydn, Lacroix and Vaienti (2005 Ann. Probab. 33 2043-50) proved that, for a given ergodic map, the entry time distribution converges in the small target limit, if and only if the corresponding return time distribution converges. The present note explains how entry and return times can be interpreted in terms of stationary point processes and their Palm distribution. This permits a generalization of the results by Haydn et al to non-ergodic maps and continuous-time dynamical systems. The research leading to these results has received funding from the European Research Council under the European Union’s Seventh Framework Programme (FP/2007-2013) / ERC Grant Agreement n. 291147

  15. QA4ECV: Developing Metrological Traceability Through ECV Products

    NASA Astrophysics Data System (ADS)

    Nightingale, Joanne; Scanlon, Tracy; Farquhar, Clive

    2015-04-01

    Meteorological traceability is the relation of the result to a reference (for example SI) through an unbroken chain of documented calibrations or comparisons. Each link in the chain contributes to the uncertainty associated with the derived value. The QA4ECV project (which has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under QA4ECV grant agreement no. 607405) aims to demonstrate traceability through the processing steps associated with the production and validation of 6 Essential Climate Variable (ECV) products (3 land and 3 atmosphere). This involves the development of ECV algorithm and product validation diagrams and demonstrable uncertainty estimation processes through each step of these chains. A traceability and uncertainty propagation tool (TUPT), which graphically demonstrates the propagation of uncertainties through an algorithm and product validation chain will be developed to support a pioneering and robust quality assurance framework for ECV climate data records.

  16. Drying of a coffee drop: differences between dry and wet tables?

    NASA Astrophysics Data System (ADS)

    Boulogne, François; Ingremeau, François; Stone, Howard

    2015-11-01

    We have all experienced that a coffee drop drying on a table leaves a ring stain. The radial flow in the drop coupled with a larger drying flux at its edge are the reasons for the particle accumulation in the liquid wedge. However, if the substrate is wet, the liquid surrounding the drop modifies the vapor distribution, and thus the drop evaporation dynamics. Our experimental observations show that the drying kinetics and the particle motion are affected by the ambient conditions. We rationalize our experimental findings with a model that describes the spatially varying evaporation as well as the temporal evolution of the particles forming the ring. We believe that these results are of practical interest for printing applications involving multiple drop systems or drying surfaces. F.B. acknowledges that the research leading to these results received funding from the People Programme (Marie Curie Actions) of the European Union's Seventh Framework Programme (FP7/2007-2013) under REA grant agreement 623541.

  17. Tissue distribution and fate of persistent organic pollutants in Indo-Pacific humpback dolphins from the Pearl River Estuary, China.

    PubMed

    Gui, Duan; Yu, Riqing; He, Xuan; Tu, Qin; Wu, Yuping

    2014-09-15

    Eleven persistent organic pollutant (POP) compounds including ∑PCBs, ∑DDTs, ∑HCHs, aldrin, mirex, endrin, ∑CHLs, dieldrin, HCB, heptachlor and pentachlorobenzene were measured in the kidney, liver, muscle, melon and other tissues of Sousa chinensis stranded on the western coast of the Pearl River Estuary in China during 2007-2013. For most parameters of POPs measured, melon tissues contained the highest mean concentrations with the exception of aldrin, which was higher in the kidney and liver tissues. The concentrations of PCBs, DDTs, heptachlor and endrin in the melon tissue exhibited significant correlations with body length, whereas PCBs and heptachlor also displayed significant regression with age. Our studies showed hepatic concentrations of ∑DDTs, ∑HCHs and mirex in S. chinensis were generally higher than those found in cetaceans from other geographic locations. The high levels of POP residues in the testis of one male dolphin suggested an increasing risk of infertility in the species.

  18. [European Union funds and clinical toxicology].

    PubMed

    Wiszniewiecka, Monika; Cejrowski, Daniel; Sein Anand, Jacek

    2015-01-01

    Since 2014 we are heading the third programming period of help from European Union (EU). The new budget will run until 2020. From common resources of EU, 106 billion euro will reach Poland, of which about 82.3 billion to cohesion policy, levelling differences of regional development. Clinical toxicology centres will be able to apply for funding under the allocation for the health service. Polish health service very actively benefited from EU funds in previous programming periods, between 2004-2006, and 2007-2013. Thanks to grants from the EU, a large number of health centres were built or renovated. Unfortunately the needs of hospitals, which were underinvested for many years, exceeded available funds according to UE programmes. Except investment projects, also projects training of health professionals were executed. In the current programming period European Union will still support projects aimed at health service. Clinical toxicology centres should have a try of using this period to fulfil their plans.

  19. Diffraction of walking droplets

    NASA Astrophysics Data System (ADS)

    Harris, Daniel M.; Pucci, Giuseppe; Bush, John W. M.

    2014-11-01

    We present results from our revisitation of the experiment of a walking droplet passing through a single slit, originally investigated by Couder & Fort (PRL, 2006). On each passage, the walker's trajectory is deviated as a result of the spatial confinement of its guiding wave. We explore the role of the droplet size and the bath's vibration amplitude on both the dynamics and statistics. We find the behavior to be remarkably sensitive to these control parameters. A complex physical picture emerges. The authors gratefully acknowledge the financial support of the NSF through Grant CMMI-1333242, DMH through the NSF Graduate Research Fellowship Program, and GP through the Programma Operativo Regionale (POR) Calabria - FSE 2007/2013.

  20. Direct sunlight facility for testing and research in HCPV

    NASA Astrophysics Data System (ADS)

    Sciortino, Luisa; Agnello, Simonpietro; Barbera, Marco; Bonsignore, Gaetano; Buscemi, Alessandro; Candia, Roberto; Cannas, Marco; Collura, Alfonso; Di Cicca, Gaspare; Gelardi, Franco Mario; Cicero, Ugo Lo; Montagnino, Fabio Maria; Napoli, Gianluca; Paredes, Filippo; Spallino, Luisa; Varisco, Salvo

    2014-09-01

    A facility for testing different components for HCPV application has been developed in the framework of "Fotovoltaico ad Alta Efficienza" (FAE) project funded by the Sicilian Regional Authority (PO FESR Sicilia 2007/2013 4.1.1.1). The testing facility is equipped with an heliostat providing a wide solar beam inside the lab, an optical bench for mounting and aligning the HCPV components, electronic equipments to characterize the I-V curves of multijunction cells operated up to 2000 suns, a system to circulate a fluid in the heat sink at controlled temperature and flow-rate, a data logging system with sensors to measure temperatures in several locations and fluid pressures at the inlet and outlet of the heat sink, and a climatic chamber with large test volume to test assembled HCPV modules.

  1. Direct sunlight facility for testing and research in HCPV

    SciTech Connect

    Sciortino, Luisa Agnello, Simonpietro Bonsignore, Gaetano; Cannas, Marco; Gelardi, Franco Mario; Napoli, Gianluca; Spallino, Luisa; Barbera, Marco; Buscemi, Alessandro; Montagnino, Fabio Maria; Paredes, Filippo; Candia, Roberto; Collura, Alfonso; Di Cicca, Gaspare; Cicero, Ugo Lo; Varisco, Salvo

    2014-09-26

    A facility for testing different components for HCPV application has been developed in the framework of 'Fotovoltaico ad Alta Efficienza' (FAE) project funded by the Sicilian Regional Authority (PO FESR Sicilia 2007/2013 4.1.1.1). The testing facility is equipped with an heliostat providing a wide solar beam inside the lab, an optical bench for mounting and aligning the HCPV components, electronic equipments to characterize the I-V curves of multijunction cells operated up to 2000 suns, a system to circulate a fluid in the heat sink at controlled temperature and flow-rate, a data logging system with sensors to measure temperatures in several locations and fluid pressures at the inlet and outlet of the heat sink, and a climatic chamber with large test volume to test assembled HCPV modules.

  2. Dietary and medication adjustments to improve seizure control in patients treated with the ketogenic diet

    PubMed Central

    Selter, Jessica H.; Turner, Zahava; Doerrer, Sarah C.; Kossoff, Eric H.

    2014-01-01

    Unlike anticonvulsant drugs and vagus nerve stimulation, there are no guidelines regarding adjustments to ketogenic diet regimens to improve seizure efficacy once the diet has been started. A retrospective chart review was performed of 200 consecutive patients treated with the ketogenic diet at Johns Hopkins Hospital from 2007-2013. Ten dietary and supplement changes were identified, along with anticonvulsant adjustments. A total of 391 distinct interventions occurred, of which 265 were made specifically to improve seizure control. Adjustments lead to >50% further seizure reduction in-18%, but only 3% became seizure-free. The benefits of interventions did not decrease over time. There was a trend towards medication adjustments being more successful than dietary modifications (24% vs. 15%, p = 0.08). No single dietary change stood out as the most effective, but calorie changes were largely unhelpful (10% with additional benefit). PMID:24859788

  3. Determination of impurities and counterions of pharmaceuticals by capillary electromigration methods.

    PubMed

    Stěpánová, Sille; Kašička, Václav

    2014-08-01

    The review presents a survey of recent applications of high-performance capillary electromigration methods-capillary zone electrophoresis, nonaqueous capillary electrophoresis, capillary isotachophoresis, micellar electrokinetic chromatography, microemulsion electrokinetic chromatography and capillary electrochromatography-for the determination of impurities of pharmaceuticals, including chiral impurities, for the period 2007-2013. In addition, due to the missing evaluation of the determination of counterions of pharmaceuticals by capillary electromigration methods in the last 20 years, the publications dealing with this topic since 1995 are included in this review. General aspects of both these types of applications of capillary electromigration methods in pharmaceutical analysis are discussed, and detailed experimental conditions used for determination of various chemical impurities and counterions of many particular drugs are described.

  4. Functionalization of plasma synthesized advanced carbons

    NASA Astrophysics Data System (ADS)

    Kovacevic, Eva; Labbaye, Thibault; Berndt, Johannes; Strunskus, Thomas; Tatarova, Elena; Henriques, Julio; Boulmer-Leborgne, Chantal

    2014-10-01

    We report here about experiments concerning the plasma based functionalization of plasma produced carbon nanotubes and free-standing graphenes. The influence of nitrogen and ammonia plasma on the surface properties is investigated, involving the role of the surface temperature on the functionalization procedure. The effect of the plasma treatment on the different carbon materials is analyzed by means of contact angle measurements, near edge x-ray absorption fine spectroscopy (NEXAFS) and XPS. We will discuss the importance of the plasma characteristics for the formation of amino groups and nitrogen incorporation in the material. The important issues concern: the formation of dangling bonds, destructive effects of plasma-surface interactions and recovery of the surfaces. The research leading to these results has received funding from the European Community's Seventh Framework Programme (FP7/2007-2013) under Grant Agreement No. 312284.

  5. Brain glioma growth model using reaction-diffusion equation with viscous stress tensor on brain MR images.

    PubMed

    Yuan, Jianjun; Liu, Lipei

    2016-02-01

    In this paper, a new reaction-diffusion model with viscous stress tensor is proposed for modeling the diffusion and invasion of brain glioma cells, which is based on the model in Yuan J.J., Liu L., Hu Q.M. Mathematical modeling of brain glioma growth using modified reaction-diffusion equation on brain MR images. Comput Biol Med 2013;43:2007-2013. The corresponding parameters are computed. The viscous stress tensor is introduced into reaction-diffusion equation, and can describe more accurately the adhesion of gliomas and normal cells. The experimental results demonstrate the effectiveness and accuracy of the proposed reaction-diffusion equation with viscous stress tensor for real brain glioma MR images. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. A historical analysis of natural gas demand

    NASA Astrophysics Data System (ADS)

    Dalbec, Nathan Richard

    This thesis analyzes demand in the US energy market for natural gas, oil, and coal over the period of 1918-2013 and examines their price relationship over the period of 2007-2013. Diagnostic tests for time series were used; Augmented Dickey-Fuller, Kwiatkowski-Phillips-Schmidt-Shin, Johansen cointegration, Granger Causality and weak exogeneity tests. Directed acyclic graphs were used as a complimentary test for endogeneity. Due to the varied results in determining endogeneity, a seemingly unrelated regression model was used which assumes all right hand side variables in the three demand equations were exogenous. A number of factors were significant in determining demand for natural gas including its own price, lagged demand, a number of structural break dummies, and trend, while oil indicate some substitutability with natural gas. An error correction model was used to examine the price relationships. Natural gas price was found not to have a significant cointegrating vector.

  7. Early screening for type 2 diabetes following gestational diabetes mellitus in France: hardly any impact of the 2010 guidelines.

    PubMed

    Goueslard, K; Cottenet, J; Mariet, A-S; Sagot, P; Petit, J-M; Quantin, C

    2017-07-01

    Women who had gestational diabetes mellitus (GDM) have a high risk of type 2 diabetes mellitus (T2DM) in the years following pregnancy. Most follow-up screening studies have been conducted in limited geographical areas leading to large variability in the results. The aim of our investigation was to measure how the publication of guidelines affected early screening for T2DM after a pregnancy with GDM during the period 2007-2013, in France. We conducted a retrospective cohort study in a representative sample of 1/97th of the French population using data from the "National Health Insurance Inter-Regime Information System," which collects individual hospital and non-hospital data for healthcare consumption. The sample included 49,080 women who gave birth in 2007-2013. In the following 3 months, only 18.49% of women with GDM had an oral glucose tolerance test or a blood glucose test in 2007. This rate had not significantly increased in 2013 (p = 0.18). The proportion of women with GDM who had the recommended glycemic follow-up at 3 months (20.30 vs. 21.58%, p = 0.19) and 6 months (32.48 vs. 37.16%, p = 0.08) was not significantly different before the guidelines (2008-2009) and after the guidelines (2012-2013). At 12 months, the difference was significant (46.77 vs. 54.05%, p = 0.009). Postpartum screening has improved only slightly since the guidelines and remains largely insufficient, with less than 25% of women with GDM screened in the first 3 months. In the first year after delivery, less than 60% of women were screened for T2DM.

  8. The PLATINO study: description of the distribution, stability, and mortality according to the Global Initiative for Chronic Obstructive Lung Disease classification from 2007 to 2017.

    PubMed

    Menezes, Ana M; Wehrmeister, Fernando C; Perez-Padilla, Rogelio; Viana, Karynna P; Soares, Claudia; Müllerova, Hana; Valdivia, Gonzalo; Jardim, José R; Montes de Oca, Maria

    2017-01-01

    The Global Initiative for Chronic Obstructive Lung Disease (GOLD) report provides a framework for classifying COPD reflecting the impacts of disease on patients and for targeting treatment recommendations. The GOLD 2017 introduced a new classification with 16 subgroups based on a composite of spirometry and symptoms/exacerbations. Data from the population-based PLATINO study, collected at baseline and at follow-up, in three sites in Latin America were analyzed to compare the following: 1) the distribution of COPD patients according to GOLD 2007, 2013, and 2017; 2) the stability of the 2007 and 2013 classifications; and 3) the mortality rate over time stratified by GOLD 2007, 2013, and 2017. Of the 524 COPD patients evaluated, most of them were classified as Grade I or II (GOLD 2007) and Group A or B (GOLD 2013), with ≈70% of those classified as Group A in GOLD 2013 also classified as Grade I in GOLD 2007 and the highest percentage (41%) in Group D (2013) classified as Grade III (2007). According to GOLD 2017, among patients with Grade I airflow limitation, 69% of them were categorized into Group A, whereas Grade IV patients were more evenly distributed among Groups A-D. Most of the patients classified by GOLD 2007 remained in the same airflow limitation group at the follow-up; a greater temporal variability was observed with GOLD 2013 classification. Incidence-mortality rate in patients classified by GOLD 2007 was positively associated with increasing severity of airflow obstruction; for GOLD 2013 and GOLD 2017 (Groups A-D), highest mortality rates were observed in Groups C and D. No clear pattern was observed for mortality across the GOLD 2017 subgroups. The PLATINO study data suggest that GOLD 2007 classification shows more stability over time compared with GOLD 2013. No clear patterns with respect to the distribution of patients or incidence-mortality rates were observed according to GOLD 2013/2017 classification.

  9. Global demand for gold is another threat for tropical forests

    NASA Astrophysics Data System (ADS)

    Alvarez-Berríos, Nora L.; Aide, T. Mitchell

    2015-01-01

    The current global gold rush, driven by increasing consumption in developing countries and uncertainty in financial markets, is an increasing threat for tropical ecosystems. Gold mining causes significant alteration to the environment, yet mining is often overlooked in deforestation analyses because it occupies relatively small areas. As a result, we lack a comprehensive assessment of the spatial extent of gold mining impacts on tropical forests. In this study, we provide a regional assessment of gold mining deforestation in the tropical moist forest biome of South America. Specifically, we analyzed the patterns of forest change in gold mining sites between 2001 and 2013, and evaluated the proximity of gold mining deforestation to protected areas (PAs). The forest cover maps were produced using the Land Mapper web application and images from the MODIS satellite MOD13Q1 vegetation indices 250 m product. Annual maps of forest cover were used to model the incremental change in forest in ˜1600 potential gold mining sites between 2001-2006 and 2007-2013. Approximately 1680 km2 of tropical moist forest was lost in these mining sites between 2001 and 2013. Deforestation was significantly higher during the 2007-2013 period, and this was associated with the increase in global demand for gold after the international financial crisis. More than 90% of the deforestation occurred in four major hotspots: Guianan moist forest ecoregion (41%), Southwest Amazon moist forest ecoregion (28%), Tapajós-Xingú moist forest ecoregion (11%), and Magdalena Valley montane forest and Magdalena-Urabá moist forest ecoregions (9%). In addition, some of the more active zones of gold mining deforestation occurred inside or within 10 km of ˜32 PAs. There is an urgent need to understand the ecological and social impacts of gold mining because it is an important cause of deforestation in the most remote forests in South America, and the impacts, particularly in aquatic systems, spread well

  10. The PLATINO study: description of the distribution, stability, and mortality according to the Global Initiative for Chronic Obstructive Lung Disease classification from 2007 to 2017

    PubMed Central

    Menezes, Ana M; Wehrmeister, Fernando C; Perez-Padilla, Rogelio; Viana, Karynna P; Soares, Claudia; Müllerova, Hana; Valdivia, Gonzalo; Jardim, José R; Montes de Oca, Maria

    2017-01-01

    Background The Global Initiative for Chronic Obstructive Lung Disease (GOLD) report provides a framework for classifying COPD reflecting the impacts of disease on patients and for targeting treatment recommendations. The GOLD 2017 introduced a new classification with 16 subgroups based on a composite of spirometry and symptoms/exacerbations. Methods Data from the population-based PLATINO study, collected at baseline and at follow-up, in three sites in Latin America were analyzed to compare the following: 1) the distribution of COPD patients according to GOLD 2007, 2013, and 2017; 2) the stability of the 2007 and 2013 classifications; and 3) the mortality rate over time stratified by GOLD 2007, 2013, and 2017. Results Of the 524 COPD patients evaluated, most of them were classified as Grade I or II (GOLD 2007) and Group A or B (GOLD 2013), with ≈70% of those classified as Group A in GOLD 2013 also classified as Grade I in GOLD 2007 and the highest percentage (41%) in Group D (2013) classified as Grade III (2007). According to GOLD 2017, among patients with Grade I airflow limitation, 69% of them were categorized into Group A, whereas Grade IV patients were more evenly distributed among Groups A–D. Most of the patients classified by GOLD 2007 remained in the same airflow limitation group at the follow-up; a greater temporal variability was observed with GOLD 2013 classification. Incidence-mortality rate in patients classified by GOLD 2007 was positively associated with increasing severity of airflow obstruction; for GOLD 2013 and GOLD 2017 (Groups A–D), highest mortality rates were observed in Groups C and D. No clear pattern was observed for mortality across the GOLD 2017 subgroups. Conclusion The PLATINO study data suggest that GOLD 2007 classification shows more stability over time compared with GOLD 2013. No clear patterns with respect to the distribution of patients or incidence-mortality rates were observed according to GOLD 2013/2017 classification. PMID

  11. Twenty-five years of research on the effects of exercise training in breast cancer survivors: A systematic review of the literature

    PubMed Central

    Battaglini, Claudio L; Mills, Robert C; Phillips, Brett L; Lee, Jordan T; Story, Christina E; Nascimento, Marcelo GB; Hackney, Anthony Carl

    2014-01-01

    AIM: To investigate the role of exercise training the past 25 years on major physiological-psychological outcomes studied thus far in this patient population. METHODS: PubMed, MedlinePlus, the Cochrane Library, Web of Science, SportDiscus, Embase, Scorpus, and Google Scholar were searched from September to November 2013 to identify exercise training studies that used objective measurements of fitness and/or patient reported outcomes assessed pre and post-exercise training with statistical analyses performed in at least one of the following outcome measurements: Cardiorespiratory function, body composition, muscular strength, fatigue, depression, and overall quality of life. Five reviewers independently identified the studies that met the criteria for the review and discrepancies were resolved by consensus among all authors. RESULTS: Fifty-one studies were included in this review with 5 from the period between 1989-1999, 11 from 2000-2006, and 35 from 2007-2013. The evolution of study designs changed from aerobic only exercise training interventions (1989-1999), to a combination of aerobic and resistance training (2000-2006), to studies including an arm of resistance training or examining the effects of resistance training as the main mode of exercise (2007-2013). Overall, the benefits of exercise showed improvements in cardiorespiratory function, body composition, strength, and patient reported outcomes including fatigue, depression, and quality of life. CONCLUSION: Exercise training appears to be safe for most breast cancer patients and improvements in physiological, psychological, and functional parameters can be attained with regular participation in moderate intensity exercise. PMID:24829866

  12. A 'test and treat' prevention strategy in Australia requires innovative HIV testing models: a cohort study of repeat testing among 'high-risk' men who have sex with men.

    PubMed

    Wilkinson, Anna L; El-Hayek, Carol; Spelman, Tim; Fairley, Christopher K; Leslie, David; McBryde, Emma S; Hellard, Margaret; Stoové, Mark

    2016-09-01

    HIV diagnoses among men who have sex with men (MSM) in several high-income countries, including Australia, have increased substantially over recent years. Australia, in line with global prevention strategies, has emphasised a 'test and treat' HIV prevention strategy which relies on timely detection of HIV through frequent testing by those at risk. We examined trends in repeat testing among MSM defined as 'high-risk' according to Australian testing guidelines. HIV test records from MSM attending high caseload clinics in Melbourne 2007-2013 and classified as high-risk were analysed. Binary outcomes of 'test within 3 months' and 'test within 6 months' were assigned to tests within individuals' panel of records. Negative binomial regressions assessed trends in overall HIV testing and returning within 3 and 6 months. Annualised proportions of return tests (2007-2012) were compared using two-sample z tests. Across 18 538 tests among 7117 high-risk MSM attending primary care clinics in Melbourne (2007-2013), the number of annual HIV tests increased (p<0.01). Between 2007 and 2012 annualised proportions of tests with a subsequent test within 3 and 6 months also increased (p<0.01); however, by 2012 only 36.4% and 15.1% of tests were followed by another test inside 6 and 3 months, respectively. Repeat testing among high-risk MSM in Australia remains unacceptably low, with recent modest increases in testing unlikely to deliver meaningful prevention impact. Removing known barriers to HIV testing is needed to maximise the potential benefit of test and treat-based HIV prevention. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  13. Basal cell carcinoma in farmers: an occupation group at high risk.

    PubMed

    Szewczyk, Mateusz; Pazdrowski, Jakub; Golusiński, Paweł; Dańczak-Pazdrowska, Aleksandra; Łuczewski, Łukasz; Marszałek, Sławomir; Majchrzak, Ewa; Golusiński, Wojciech

    2016-04-01

    Skin cancer is the most commonly diagnosed cancer type worldwide, and 80 % of skin cancers are basal cell carcinoma (BCC). The main risk factor for developing BCC is exposure to ultraviolet radiation (UVR), particularly high-dose exposure at a young age. Outdoor workers, particularly farmers, are at high risk of developing BCC. However, studies of BCC in this population are scant. To comprehensively evaluate all cases of BCC of the head and neck region treated during the years 2007-2013 at our hospital in Poland, and to compare the tumour characteristics in farmers to non-farmers. Retrospective analysis of 312 patients treated for head and neck BCC during the study period (2007-2013). Most patients (198 cases; 63 %) were males, with 114 females (37 %). Median age was 73 years (range 32-96 years). The most common tumour location was the nose and cheek (114 pts; 37 %) followed by the auricle (82 pts; 26 %), lips (54 pts; 18 %), scalp (26 pts; 8 %), and eye (36 pts; 12 %). The most common disease stage on presentation was stage T2 (104 pts, 33 %), followed by stage T1 (79 pts; 25 %), stage T3 (89 pts; 28 %), and stage T4 (40 pts; 14 %). By occupation, farmers accounted for 33 % of all patients (102 of 312 pts). The most common tumour localisations in the farmer subgroup were the nose and cheek (50 pts; 49 %; p < 0.001; odds ratio [OR] 2.19; 95 % confidence interval [CI] 1.35-3.57), followed by the auricle (32 pts; 31 %), scalp (16 pts; 16 %), ocular region (3 pts; 3 %), and lips (1 pt; 1 %). Patients in the farmer group were significantly younger than non-farmers (62 vs. 73 years; p < 0.001; OR 0.90, 95 % CI 0.88-0.93). Farmers were significantly more likely to present disease recurrence (27 vs. 12 % of cases; p < 0.001; OR 5.94; 95 % CI 2.86-12.33). The results highlight the increased incidence and risk of recurrence of BCC in farmers. It is therefore necessary to consider enhancing educational programmes and other preventative measures in this occupational group and

  14. Temporal changes in sugar-sweetened soft drink intake and variation across municipalities in the Capital Region of Denmark.

    PubMed

    Bernsdorf, Kamille Almer; Lau, Cathrine Juel; Robinson, Kirstine; Toft, Ulla; Andreasen, Anne Helms; Glümer, Charlotte

    2016-12-01

    We aimed to examine the changes in sugar-sweetened soft drink intake across the Capital Region of Denmark from 2007 to 2013 and to examine the association between intake and neighbourhood socioeconomic status. The study included data from three health surveys in 2007 (n = 30,426), 2010 (n = 42,218) and 2013 (n = 34,330) in the Capital Region of Denmark. Frequency of soft drink intake was derived from questionnaires among residents aged 25-79 years and linked with information from central registers. Municipality social groups (MSG) 1-4 of decreasing affluence were defined as a composite measure. Logistic regression analyses were conducted for individuals with an appropriate soft drink intake (< once/week) and for individuals with a frequent soft drink intake (≥ 3 times/week). The proportion of individuals reporting an appropriate soft drink intake increased by 71% during 2007-2013 (p < 0.0001). A corresponding decrease was found in the proportion of individuals reporting a frequent soft drink intake. Compared to MSG 1, odds of an appropriate soft drink intake were significantly lower in MSG 3-4: OR = 0.87 (95%CI 0.83-0.91) and OR = 0.89 (95%CI 0.85-0.92), respectively. Compared to MSG 1, odds of a frequent soft drink intake were significantly higher in MSG 3-4: OR = 1.24 (95%CI 1.63-1.31) and 1.17 (95%CI 1.10-1.25), respectively. A significant interaction between MSG and educational level was found among individuals reporting a frequent soft drink intake (p = 0.02). The results show an encouraging reduction in frequency of soft drink intake among capital residents in the period of 2007-2013. A social gradient was observed in soft drink intake across MSG.

  15. Geodiversity and geohazards of the Susa Valley (W-Alps, Italy): combining scientific research and new technologies for enhanced knowledge and proactive management of geoheritage in mountain regions

    NASA Astrophysics Data System (ADS)

    Giardino, Marco; Bacenetti, Marco; Perotti, Luigi; Giordano, Enrico; Ghiraldi, Luca; Palomba, Mauro

    2013-04-01

    Mountain regions have a range of geological and geomorphological features that make them very attractive for tourism activities. As a consequence, increased human "pressure" causes impacts on geoheritage sites and higher geomorphological risks. These effects are magnified by active geomorphic processes characterizing mountains areas, highly sensitive to climate change. In term of "human sensitivity", several sociological surveys have shown that "perceived risk", not "real risk", influences people's behavior towards natural hazards. The same approach can be applied to geodiversity and geoheritage. Based on these assumptions, we considered the possible strategic roles played by diffusion of scientific research and application of new technologies: 1) to enhance awareness, either of geodiversity or environmental dynamics and 2) to improve knowledge, both on geoheritage management and natural risk reduction. Within the activities of the "ProGEO-Piemonte Project" (Progetti d'Ateneo 2011, cofunded by Universita? degli Studi di Torino and Compagnia di San Paolo Bank Foundation), we performed a systematic review of geodiversity and natural hazards information in the Piemonte Region (NW-Italy). Then we focused our attention on the Susa Valley, an area of the Western Alps where the geoheritage is affected by very active morphodynamics, as well as by a growing tourism, after the 2006 winter Olympics. The Susa Valley became one of the 9 strategic geothematic areas have been selected to represent the geodiversity of the Piemonte region, each characterized by high potential for enhancement of public understanding of science, and recreation activities supported by local communities. Then we contributed to the awareness-raising communication strategy of the "RiskNat project" (Interreg Alcotra 2007-2013, Action A.4.3) by synthesizing geoscience knowledge on the Susa Valley and information on slope instabilities and models/prevention measures/warning systems. Visual representations

  16. Office-Based Opioid Treatment with Buprenorphine (OBOT-B): Statewide Implementation of the Massachusetts Collaborative Care Model in Community Health Centers.

    PubMed

    LaBelle, Colleen T; Han, Steve Choongheon; Bergeron, Alexis; Samet, Jeffrey H

    2016-01-01

    We describe a Massachusetts Bureau of Substance Abuse Services' (BSAS) initiative to disseminate the office-based opioid treatment with buprenorphine (OBOT-B) Massachusetts Model from its development at Boston Medical Center (BMC) to its implementation at fourteen community health centers (CHCs) beginning in 2007. The Massachusetts Collaborative Care Model for the delivery of opioid agonist therapy with buprenorphine, in which nurses working with physicians play a central role in the evaluation and monitoring of patients, holds promise for the effective expansion of treatment for opioid use disorders. The training of and technical assistance for the OBOT nurses as well as a limited program assessment are described. Data spanning 6years (2007-2013) report patient demographics, prior treatment for opioid use disorders, history of overdose, housing, and employment. The expansion of OBOT to the fourteen CHCs increased the number of physicians who were "waivered" (i.e., enabling their prescribing of buprenorphine) by 375%, from 24 to 114, within 3years. During this period the annual admissions of OBOT patients to CHCs markedly increased. Dissemination of the Massachusetts Model of the Office-Based Opioid Treatment with Buprenorphine employing a collaborative care model with a central role for nursing enabled implementation of effective treatment for patients with an opioid use disorder at community health centers throughout Massachusetts while effectively engaging primary care physicians in this endeavor. Copyright © 2015 Elsevier Inc. All rights reserved.

  17. Role of FNAC in the diagnosis of intraosseous jaw lesions

    PubMed Central

    Goyal, Surbhi; Kotru, Mrinalini; Gupta, Neelima

    2015-01-01

    Background FNAC of intraosseous jaw lesions has not been widely utilized for diagnosis due to rarity and diversity of these lesions, limited experience and lack of well established cytological features. Aim of the study was to determine the role of FNAC in the diagnosis of intraosseous jaw swellings. Material and Methods 42 patients underwent FNAC over a period of 7 years (2007-2013), of which 37 (88.1%) aspirates were diagnostic. Histopathology correlation was available in 33 cases and diagnostic accuracy of FNAC was calculated. Results Lesions were categorized into inflammatory 3, cysts/hamartomas 15 and neoplasms 19. Mandibular and maxillary involvement was seen in 21 and 16 patients respectively. Of these, benign cysts and malignant lesions were commonest, accounting for 27% lesions (10 cases) each. One case of cystic ameloblastoma was misdiagnosed as odontogenic cyst on cytology. Overall, sensitivity and specificity of FNAC were 94.7% and 100% respectively with a diagnostic accuracy of 97.3%. Definitive categorization of giant cell lesions, fibro-osseous lesions, odontogenic tumors and cystic lesions was not feasible on FNAC. Conclusions FNAC is a simple, safe and minimally invasive first line investigation which can render an accurate preoperative diagnosis of intraosseous jaw lesions, especially the malignant ones in the light of clinic-radiological correlation. Key words: Jaw swellings, intraosseous, FNAC. PMID:25662547

  18. Km3Net Italy - Seafloor network

    NASA Astrophysics Data System (ADS)

    Papaleo, Riccardo

    2016-04-01

    The KM3NeT European project aims to construct a large volume underwater neutrino telescope in the depths of the Mediterranean Sea. INFN and KM3NeT collaboration, thanks to a dedicated funding of 21.000.000 € (PON 2007-2013), are committed to build and deploy the Phase 1 of the telescope, composed of a network of detection units: 8 towers, equipped with single photomultiplier optical modules, and 24 strings, equipped with multi-photomultipliers optical modules. All the towers and strings are connected to the main electro optical cable by means of a network of junction boxes and electro optical interlink cables. Each junction box is an active node able to provide all the necessary power to the detection units and to guarantee the data transmission between the detector and the on-shore control station. The KM3NeT Italia project foresees the realization and the installation of the first part of the deep sea network, composed of three junction boxes, one for the towers and two for the strings. In July 2015, two junction boxes have been deployed and connected to the new cable termination frame installed during the same sea campaign. The third and last one will be installed in November 2015. The status of the deep sea network is presented together with technical details of the project.

  19. Genetic characteristics of Streptococcus dysgalactiae isolated from cage cultured cobia, Rachycentron canadum (L.).

    PubMed

    Tsai, M-A; Wang, P-C; Yoshida, T; Chen, S-C

    2015-12-01

    Disease outbreaks occurred during 2007-2013 in Taiwan with 2.5-10% mortality among the cage cultured cobia, Rachycentron canadum (L.), characterized by the presence of polyserositis, pericarditis and peritonitis. The micro-organisms isolated from internal organs were Gram-positive cocci. The isolates were confirmed as Streptococcus dysgalactiae by a polymerase chain reaction assay that yielded the expected specific 259 bp amplicon. Additionally, partial sequence of the 16S-23S rDNA intergenic spacer region of the GCS strain isolates from fish was also compared and produced 100% sequence identity with S. dysgalactiae (GenBank accession number AB252398). The genetic characterization was then determined by pulsed-field gel electrophoresis (PFGE) analysis. Based on PFGE, the Apa I or Sma I digestion patterns of chromosomal DNA of these isolates were grouped into three main clusters. Taiwanese strains were divided into two clusters, and the tet(M) gene was detected in cluster 1 (pulsotypes: A1-A2 and S1-S3), but not in cluster 2 strains (pulsotypes: A3-A4 and S4-S5). Three Japanese strains from amberjack, Seriola dumerili (Risso), were grouped into cluster 3 (pulsotypes: A5-A7 and S6-S8) and displayed no mortality to cobia in the challenge experiment. Conversely, Taiwanese strains from cobia and snubnose pompano, Trachinotus blochii (L.), displayed a mortality rate of 50-87.5% in cobia.

  20. [Clinical and epidemiological changes of candidemia among adult patients from 2000 to 2013].

    PubMed

    Siri, Leonardo; Legarraga, Paulette; García, Patricia; González, Tamara; Rabagliati, Ricardo

    2017-02-01

    Invasive Candida spp. infections have been described more frequently. To characterize the epidemiological data of candidemia in recent years. A retrospective study of adult patients in a University Hospital in Santiago, Chile, with 1 or more documented episodes of candidemia, from January 2000 to December 2013. One hundred and twenty episodes of candidemia were identified in 120 patients, annual incidence of 0.4 cases per 1000 discharges, 53.3% were male patients, 58.3% > 60 years, 77,5% had at least one co-morbidity. Candida albicans was the species most frequently identified 55%, followed by C. glabrata 18.3%, C. tropicalis 11.7% and C. parapsilosis 9.2%. Comparing 2000-2006 vs 2007-2013, increased the frequency of C. parapsilosis among non-albicans and echinocandins prescription. Patients with C. albicans showed higher APACHE-II, more requirement for invasive mechanical ventilation, greater association with CVC, and shorter incubation time compared with non-albicans species. The 30-day mortality was 31.7%. During this 14-years period we observed that C. albicans was the predominant specie and more recently a change among C. non-albicans increasing C. parapsilosis and decreasing C. glabrata 30-days and attributable mortality decreased together with more echinocandins prescription.

  1. Population dynamics of the critically endangered toad Atelopus cruciger and the fungal disease chytridiomycosis.

    PubMed

    Lampo, Margarita; Señaris, Celsa; García, Carmen Zulay

    2017-01-01

    Harlequin toads (Atelopus) are among the most severely impacted amphibians by the emergence of chytridiomycosis, a fungal disease caused by the pathogen Batrachochytrium dendrobatidis (Bd). Many species disappeared while others suffered drastic contractions of their geographic distribution to lower altitudes. A diminished virulence of Bd in warm habitats was proposed to explain the survival of lowland populations of harlequin toads (i.e. thermal refuge hypothesis). To understand the mechanisms that allow some populations to reach an endemic equilibrium with this pathogen, we estimated demographic and epidemiological parameters at one remnant population of Atelopus cruciger in Venezuela using mark-recapture data from 2007-2013. We demonstrated that Bd is highly virulent for A. cruciger, increasing the odds of dying of infected adults four times in relation to uninfected ones and reducing the life expectancy of reproductive toads to a few weeks. Despite an estimated annual loss of 18% of the reproductive population due to Bd-induced mortality, this population has persisted in an endemic equilibrium for the last decade through the large recruitment of healthy adults every year. Given the high vulnerability of harlequin toads to Bd in lowland populations, thermal refuges need to be redefined as habitats of reduced transmission rather than attenuated virulence.

  2. The cascade of care to prevent mother-to-child transmission in Rio de Janeiro, Brazil, 1996-2013: improving but still some way to go.

    PubMed

    Hofer, Cristina Barroso; Egger, Matthias; Davies, Mary-Ann; Frota, Ana Cristina Cisne; de Oliveira, Ricardo Hugo; Abreu, Thalita Fernandes; Araújo, Lúcia Evangelista; Witthlin, Bernardo Bastos; Carvalho, Alice Weber; Cordeiro, Janaína Rivas; Lima, Giulia Pasqualini; Keiser, Olivia

    2017-10-01

    To describe the cascade of care to HIV mother-to-child transmission (PMTCT) in a Rio de Janeiro reference paediatric clinic and evaluate the main factors possibly associated with HIV transmission. Data on antenatal care (ANC), perinatal and neonatal assistance to HIV-infected and HIV-exposed but uninfected children assisted in the clinic from 1996 to 2013 were collected. The cascade of care was graphically demonstrated, and possible factors associated with HIV infection were described using regression models for bivariate and multivariate analysis. We imputed missing values of explanatory variables for the final model. A total of 989 children were included in the analysis: 211 were HIV and 778 HEU. Graphically, the HIV PMTCT cascade of care improved from 1996/2000 to the later periods, but not from 2001/2006 to 2007/2013. The main factor independently associated with the HIV infection over time was breastfeeding. In the period 1996/2000, the lack of antiretroviral use during labour was associated HIV transmission. While in 2001/2007, other modes of delivery but elective Caesarean section, and lack of maternal antiretroviral use during ANC were associated with HIV transmission. In the last period, the main factor associated with transmission was the lack of maternal ANC. The HIV PMTCT cascade improved over time, but HIV vertical transmission remains a problem, and better access to ANC is needed. © 2017 John Wiley & Sons Ltd.

  3. Estimated performance of an adaptive trailing-edge device aimed at reducing fuel consumption on a medium-size aircraft

    NASA Astrophysics Data System (ADS)

    Diodati, Gianluca; Concilio, Antonio; Ricci, Sergio; De Gaspari, Alessandro; Huvelin, Fabien; Dumont, Antoine; Godard, Jean-Luc

    2013-03-01

    This paper deals with the estimation of the performance of a medium-size aircraft (3-hour flight range) equipped with an adaptive trailing edge device (ATED) that runs span-wise from the wing root in the flap zone and extends chord-wise for a limited percentage of the MAC. Computations are calculated referring to the full wing and do not refer to the complete aircraft configuration. Aerodynamic computations, taking into account ideal shapes, have been performed by using both Euler and Navier- Stokes method in order to extract the wing polars for the reference and the optimal wing, implementing an ATED, deflected upwards and downwards. A comparison of the achieved results is discussed. Considering the shape domain, a suitable interpolation procedure has been set up to obtain the wing polar envelop of the adaptive wing, intended as the set of "best" values, picked by each different polar. At the end, the performances of the complete reference and adaptive wing are computed and compared for a symmetric, centered, leveled and steady cruise flight for a medium size aircraft. A significant fuel burn reduction estimate or, alternatively, an increased range capability is demonstrated, with margins of further improvements. The research leading to these results has gratefully received funding from the European Union Seventh Framework Programme (FP7/2007- 2013) under Grant Agreement n° 284562.

  4. Actuation needs for an adaptive trailing edge device aimed at reducing fuel consumption on a regional aircraft

    NASA Astrophysics Data System (ADS)

    Diodati, Gianluca; Concilio, Antonio

    2013-03-01

    This paper deals with the definition of the actuation specifications, needed to implement an Adaptive Trailing Edge Device (ATE device) for a medium-size aircraft (3-hours flight range). It is well known that the weight reduction occurring during flight as consequence of the burned fuel, moves the aerodynamic configuration through a domain that can be far away from the unique design working point. The aircraft then flies into a non-optimal pattern for a great extension of its mission. An ATE device is able to compensate these effects by modifying the wing camber and attaining significant fuel savings (estimated around 3%) or, alternatively, increasing operative range. The device architecture is basically made of a structural kinematic chain (aimed at modulating the transmitted force/displacement) and an actuator. Starting from preliminary aerodynamic calculation of the pressure field over the wing profile and a model of the segmented structure aimed at reproducing the targeted profile shapes during cruise, a multibody model has been set up. The force levels on the driving system have been then computed. Based on this information and the reference geometry, the main characteristics (as for instance, necessary actuation force, angular displacement and necessary room) have been herein calculated. The research leading to these results has been gratefully funded by the European Union inside the 7th Framework Programme (FP7/2007- 2013) under Grant Agreement n° 284562.

  5. European Union research and innovation perspectives on biotechnology.

    PubMed

    Cichocka, Danuta; Claxton, John; Economidis, Ioannis; Högel, Jens; Venturi, Piero; Aguilar, Alfredo

    2011-12-20

    "Food, Agriculture and Fisheries and Biotechnology" is one of 10 thematic areas in the Cooperation programme of the European Union's 7th Framework Programme for Research, Technological Development and Demonstration Activities (FP7). With a budget of nearly €2 billion for the period 2007-2013, its objective is to foster the development of a European Knowledge-Based Bio-Economy (KBBE) by bringing together science, industry and other stakeholders that produce, manage or otherwise exploit biological resources. Biotechnology plays an important role in addressing social, environmental and economic challenges and it is recognised as a key enabling technology in the transition to a green, low carbon and resource-efficient economy. Biotechnologies for non-health applications have received a considerable attention in FP7 and to date 61 projects on industrial, marine, plant, environmental and emerging biotechnologies have been supported with a contribution of €262.8 million from the European Commission (EC). This article presents an outlook of the research, technological development and demonstration activities in biotechnology currently supported in FP7 within the Cooperation programme, including a brief overview of the policy context.

  6. Systems and Technologies for Space Exploration: the regional project STEPS

    NASA Astrophysics Data System (ADS)

    Boggiatto, D.; Moncalvo, D.

    The Aerospace technology network of Piemonte represents ˜25% of the italian capacity and handles a comprehensive spectrum of products (aircraft, propulsion, satellites, space station modules, avionics. components, services...). The cooperation between the Comitato Distretto Aerospaziale Piemonte and the European Regional Development Fund 2007-2013 has enabled Regione Piemonte to launch three regional Projects capable to enhance the synergy and competitiveness of the network, among which: STEPS - Sistemi e Tecnologie per l'EsPlorazione Spaziale, a joint development of technologies for robotic and human Space Exploration by 3 large Industries, 27 SMEs, 3 Universities and one public Research Centre. STEPS develops virtual and hardware demonstrators for a range of technologies to do with a Lander's descent and soft landing, and a Rover's surface mobility, of both robotic and manned equipment on Moon and Mars. It also foresees the development of Teleoperations labs and Virtual Reality environments and physical simulations of Moon and Mars surface conditions and ground. Mid-way along STEPS planned development, initial results in several technology domains are available and are presented in this paper.

  7. Nuclear Fuel Traces Definition in Storage Ponds of Research VVR-2 and OR Reactors in NRC 'Kurchatov Institute'

    SciTech Connect

    Stepanov, Alexey; Simirskii, Iurii; Stepanov, Vyacheslav; Semin, Ilya; Volkovich, Anatoly

    2015-07-01

    The Gas Plant complex is the experimental base of the Institute of Nuclear Reactors, which is part of the Kurchatov Institute. In 1954 the commissioning of the first Soviet water-cooled water-moderated research reactor VVR-2 on enriched uranium, and until 1983 the complex operated two research water-cooled water-moderated reactors 3 MW (VVR-2) and 300 kW (OR) capacity, which were dismantled in connection with the overall upgrades of the complex. The complex has three storage ponds in the reactor building. They are sub-surface vessels filled with water (the volume of water in each is about 6 m{sup 3}). In 2007-2013 the spent nuclear fuel from storages was removed for processing to 'Mayk'. Survey of Storage Ponds by Underwater Collimated Spectrometric System shows a considerable layer of slime on the bottom of ponds and traces of spent nuclear fuel in one of the storage. For determination qualitative and the quantitative composition of radionuclide we made complex α-, β-, γ- spectrometric research of water and bottom slimes from Gas Plant complex storage ponds. We found the spent nuclear fuel in water and bottom slime in all storage ponds. Specific activity of radionuclides in the bottom slime exceeded specific activity of radionuclides in the ponds water and was closed to levels of high radioactive waste. Analysis of the obtained data and data from earlier investigation of reactor MR storage ponds showed distinctions of specific activity of uranium and plutonium radionuclides. (authors)

  8. Past missions - the best way to train future planetary researchers

    NASA Astrophysics Data System (ADS)

    Kozlova, Natalia; Solodovnikova, Anastasiya; Zubarev, Anatoly; Garov, Andrey; Patraty, Vyacheslav; Kokhanov, Alexander; Karachevtseva, Irina; Nadezhdina, Irina; Konopikhin, Anatoly; Oberst, Juergen

    2015-04-01

    Practice shows that it is much more interesting and useful to learn from real examples than on imaginary tasks from exercise books. The more technologies and software improves and develops, the more information and new products can be obtained from new processing of archive information collected by past planetary missions. So at MIIGAiK we carry out modern processing of lunar panoramic images obtained by Soviet Lunokhod missions (1970-1973). During two years of the study, which is a part of PRoViDE project (http://www.provide-space.eu/), many students, PhD students, young scientists, as well as professors have taken part in this research. Processing of the data obtained so long ago requires development of specific methods, techniques, special software and extraordinary approach. All these points help to interest young people in planetary science and develop their skills as researchers. Another advantage of data from previous missions is that you can compare your results with the ones obtained during the mission. This also helps to test the developed techniques and software on real data and adjust them for implementation in future missions. The work on Lunokhod data processing became the basis of master and PhD theses of MIIGAiK students and scientists at MExLab. Acknowledgments: The research leading to these results has received funding from the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement No 312377 PRoViDE.

  9. WASP-14 b: transit timing analysis of 19 light curves

    NASA Astrophysics Data System (ADS)

    Raetz, St.; Maciejewski, G.; Seeliger, M.; Marka, C.; Fernández, M.; Güver, T.; Göğüş, E.; Nowak, G.; Vaňko, M.; Berndt, A.; Eisenbeiss, T.; Mugrauer, M.; Trepl, L.; Gelszinnis, J.

    2015-08-01

    Although WASP-14 b is one of the most massive and densest exoplanets on a tight and eccentric orbit, it has never been a target of photometric follow-up monitoring or dedicated observing campaigns. We report on new photometric transit observations of WASP-14 b obtained within the framework of Transit Timing Variations @ Young Exoplanet Transit Initiative (TTV@YETI). We collected 19 light curves of 13 individual transit events using six telescopes located in five observatories distributed in Europe and Asia. From light-curve modelling, we determined the planetary, stellar, and geometrical properties of the system and found them in agreement with the values from the discovery paper. A test of the robustness of the transit times revealed that in case of a non-reproducible transit shape the uncertainties may be underestimated even with a wavelet-based error estimation methods. For the timing analysis, we included two publicly available transit times from 2007 and 2009. The long observation period of seven years (2007-2013) allowed us to refine the transit ephemeris. We derived an orbital period 1.2 s longer and 10 times more precise than the one given in the discovery paper. We found no significant periodic signal in the timing-residuals and, hence, no evidence for TTV in the system.

  10. Analysis of Bonds as an Instrument for Financing Mining Investments

    NASA Astrophysics Data System (ADS)

    Ranosz, Robert

    2017-06-01

    The purpose of this article is to examine the structure of financing for mining enterprises in the years 2007-2013, with particular emphasis on bonds. The document pays special attention to Polish mining enterprises. The financing structure analysis was based on data collected from financial statements (cash flows) of the largest mining companies in Poland, and their comparison with the results of global mining enterprises pursuant to reports prepared by international advisory firms. The article takes into account capital sources such as: corporate bonds, bank loans and issue of shares. As indicated by the performed analysis, mining enterprises both around the world and in Poland are increasingly eager to take advantage of obtaining business financing from issue of corporate bonds. It should also be recognized that in the analyzed period, both global and Polish mining enterprises deviate from forms of financing such as issue of shares. This may be caused by the fact that the bonds market in Poland is becoming increasingly popular, mainly due to interest rate on bonds being lower in comparison with bank loans. Another reason may be that banks and potential buyers of shares are less eager to finance this type of investment due to a relatively substantial risk acceptable to bondholders.

  11. Onset time estimation of eruptive filaments using Halpha line center and Doppler images.

    NASA Astrophysics Data System (ADS)

    Srivastava, Nandita

    2013-04-01

    A dual-beam H-alpha Doppler system is being developed at the Udaipur Solar Observatory (USO) in order to record images of quiet, activated and erupting filaments on the Sun, with special emphasis on the study of those that are associated with geoeffective coronal mass ejections. These H-alpha line center images will be complemented with near co-temporal Doppler images. These images can also be compared with multi-wavelength images obtained from space missions such as STEREO, SOHO and Hinode. In order to understand the potential of these observations, we have used the existing data-sets from different ground based observatories and implemented our analysis technique. The technique involves implementation of an automated detection algorithm developed by us for estimation of different attributes of a filament and study its evolution during its eruption using full disk H-alpha and Doppler images. The analysis is important for determining the exact onset time of the filament eruption based on these attributes. We also compare the onset time of eruptive filament with that of the associated CMEs observed by LASCO coronagraphs and EUV images. In this paper, we present our results to highlight the importance of such studies in understanding the mechanism of CME initiation and possible role of eruptive filaments for the same. This work contributes to the research for European Union Seventh Framework Programme (FP7/2007-2013) for the Coronal Mass Ejections and Solar Energetic Particles (COMESEP) project under Grant Agreement No. 263252.

  12. [Assessment of respiratory function in the qualification for lung cancer surgery].

    PubMed

    Franczuk, Monika; Wesołowski, Stefan

    2015-01-01

    Surgery is the treatment of choice in patients with a diagnosis of non-small cell lung cancer (NSCLC). A pivotal of eligibility for resection is the early stage of the disease and histopathological assessment. The performance status and comorbidities in population, predominated by elderly patients, also influence the therapeutic decisions. In some lung cancer patients COPD coexists, characterized by a decrease in lung function. Then the preoperative evaluation is particularly important, for both the risk of postoperative complications, lung function and quality of life postoperatively. Recently several recommendations for preoperative evaluation of patients being considered for surgery were published. The guidelines of BTS (2001, 2010), ACCP (2007, 2013) and joint recommendations of ERS and ESTS (2009) have been based on the currently available research results, and indicated the algorithms. The recommendations ERS/ESTS and ACCP distinguished cardiac risk estimation in all patients, which should precede the evaluation of lung function. According to the latest recommendations (ACCP 2013) the next step is spirometry, DLCO measurement and calculation of predicted postoperative values for both parameters. The low-technology exercise tests (stair climbing, shuttle walk test) were assigned as valuable to discriminate patients at low and intermediate perioperative risk. The cardiopulmonary exercise test (CPET) is recommended to be performed at the final qualification for surgery in patients with high risk. It was also stressed that therapeutic decisions should be taken multidisciplinary, allowing to estimate the risk of complications and to evaluate the expected quality of life in the postoperative time.

  13. Incidence and mortality of acquired brain injury in young Danish adults between 1994 and 2013: a nationwide study.

    PubMed

    Tibæk, Maiken; Forchhammer, Hysse Birgitte; Dehlendorff, Christian; Johnsen, Søren Paaske; Kammersgaard, Lars Peter

    2017-09-28

    We estimated the annually incidence and mortality of acquired brain injury (ABI) in people aged 15-30 years during 1994-2013. All Danes with a first-ever hospital diagnosis of ABI, including traumatic brain injury (TBI), encephalopathy, CNS-infection or brain tumour, were identified in the Danish National Patient Register. Incidence rates (IRs) and estimated annual percentage changes (EAPC) were estimated by Poisson regression. Mortality was estimated by the Kaplan-Meier estimator and adjusted hazard ratios (aHR) were computed using Cox regression with 1994-1998. A total of 10,542 individuals were hospitalized with a first-time diagnosis of ABI. The IR for ABI decreased from 63.36 to 33.91/100,000 person-years from 1994 to 2013 [EAPC: -2.78% (95% CI: -3.26 to -2.28)] mainly driven by a decreasing IR of TBI [EAPC: -6.53% (95% CI: -9.57 to -3.39)] during 2007-2013. IRs of brain tumour and CNS infections also decreased significantly. The mortality after ABI tended to be higher during 1999-2013 compared to 1994-1998. For brain tumour, the 1-year mortality decreased significantly [2009-2013 aHR: 0.41 (95% CI: 0.23-0.72)]. Incidence of hospitalisations for ABI and in particular TBI has decreased significantly. Overall, the mortality after ABI has not improved, but the mortality after brain tumour has decreased significantly.

  14. Experience with "Fast track" postoperative care after deep brain stimulation surgery.

    PubMed

    Martín, Nuria; Valero, Ricard; Hurtado, Paola; Gracia, Isabel; Fernández, Carla; Rumià, Jordi; Valldeoriola, Francesc; Carrero, Enrique J; Tercero, Francisco Javier; de Riva, Nicolás; Fàbregas, Neus

    A 24-h-stay in the post-anesthesia care unit (PACU) is a common postoperative procedure after deep brain stimulation surgery (DBS). We evaluated the impact of a fast-track (FT) postoperative care protocol. An analysis was performed on all patients who underwent DBS in 2 periods: 2006, overnight monitored care (OMC group), and 2007-2013, FT care (FT group). The study included 19 patients in OMC and 95 patients in FT. Intraoperative complications occurred in 26.3% patients in OMC vs. 35.8% in FT. Post-operatively, one patient in OMC developed hemiparesis, and agitation in 2 patients. In FT, two patients with intraoperative hemiparesis were transferred to the ICU. While on the ward, 3 patients from the FT developed hemiparesis, two of them 48h after the procedure. Thirty eight percent of FT had an MRI scan, while the remaining 62% and all patients of OMC had a CT-scan performed on their transfer to the ward. One patient in OMC had a subthalamic hematoma. Two patients in FT had a pallidal hematoma, and 3 a bleeding along the electrode. A FT discharge protocol is a safe postoperative care after DBS. There are a small percentage of complications after DBS, which mainly occur within the first 6h. Copyright © 2016 Sociedad Española de Neurocirugía. Publicado por Elsevier España, S.L.U. All rights reserved.

  15. Socioeconomic Differences in Use of Low-Value Cancer Screenings and Distributional Effects in Medicare.

    PubMed

    Xu, Wendy Yi; Jung, Jeah Kyoungrae

    2017-10-01

    Consuming low-value health care not only highlights inefficient resource use but also brings an important concern regarding the economics of disparities. We identify the relation of socioeconomic characteristics to the use of low-value cancer screenings in Medicare fee-for-service (FFS) settings, and quantify the amount subsidized from nonusers and taxpayers to users of these screenings. 2007-2013 Medicare Current Beneficiary Survey, Medicare FFS claims, and the Area Health Resource Files. Our sample included enrollees in FFS Part B for the entire calendar year. We excluded beneficiaries with a claims-documented or self-reported history of targeted cancers, or those enrolled in Medicaid or Medicare Advantage plans. We identified use of low-value Pap smears, mammograms, and prostate-specific antigen tests based on established algorithms, and estimated a logistic model with year dummies separately for each test. Secondary data analyses. We found a statistically significant positive association between privileged socioeconomic characteristics and use of low-value screenings. Having higher income and supplemental private insurance strongly predicted more net subsidies from Medicare. FFS enrollees who are better off in terms of sociodemographic characteristics receive greater subsidies from taxpayers for using low-value cancer screenings. © Health Research and Educational Trust.

  16. Lipid-based nanocarriers for drug delivery and targeting: a patent survey of methods of production and characterization.

    PubMed

    Carbone, Claudia; Cupri, Sarha; Leonardi, Antonio; Puglisi, Giovanni; Pignatello, Rosario

    2013-09-01

    Among the colloidal vectors proposed for the controlled delivery and targeting of drugs and other biologically active compounds, lipid-based nanocarriers are acquiring an increasing role due to a number of peculiar technological and physical features. Solid lipid nanoparticles, lipid nanocapsules, nanostructured lipid carriers, and drug-lipid conjugates are all examples of how it can be possible to combine the properties of the more acknowledged liposomal systems, such as biocompatibility and biodegradability, with the stability and compositional flexibility, distinctive of polymeric nanosystems. This article introduces recent patents, filed in years 2007-2013, that deal with novel or amended methods of production of the various types of lipid-based nanocarriers. Although a significant gap still remains between basic research and patenting activity in this field, many of the proposed methods can attain an industrial value. Furthermore, the critical analysis of these patents further supports the position that a general revision of patenting systems at an international level would be necessary for nanosized pharmaceutical systems.

  17. Exponential Runge-Kutta integrators for modelling Predator-Prey interactions

    NASA Astrophysics Data System (ADS)

    Diele, F.; Marangi, C.; Ragni, S.

    2012-09-01

    Spatially explicit models consisting of reaction-diffusion partial differential equations are considered in order to model prey-predator interactions, since it is known that the role of spatial processes reveals of great interest in the study of the effects of habitat fragmentation on biodiversity. As almost all of the realistic models in biology, these models are nonlinear and their solution is not known in closed form. Our aim is approximating the solution itself by means of exponential Runge-Kutta integrators. Moreover, we apply the shift-and-invert Krylov approach in order to evaluate the entire functions needed for implementing the exponential method. This numerical procedure reveals to be very eff cient in avoiding numerical instability during the simulation, since it allows us to adopt high order in the accuracy. This work has received funding from the European Union's Seventh Framework Programme FP7/2007-2013, SPA.2010.1.1-04: "Stimulating the development of GMES services in specif c are", under grant agreement 263435, project title: Biodiversity Multi-Source Monitoring System:from Space To Species (BIOSOS) coordinated by CNR-ISSIA, Bari-Italy (http://www.biosos.eu).

  18. Finite volume methods for submarine debris flows and generated waves

    NASA Astrophysics Data System (ADS)

    Kim, Jihwan; Løvholt, Finn; Issler, Dieter

    2016-04-01

    Submarine landslides can impose great danger to the underwater structures and generate destructive tsunamis. Submarine debris flows often behave like visco-plastic materials, and the Herschel-Bulkley rheological model is known to be appropriate for describing the motion. In this work, we develop numerical schemes for the visco-plastic debris flows using finite volume methods in Eulerian coordinates with two horizontal dimensions. We provide parameter sensitivity analysis and demonstrate how common ad-hoc assumptions such as including a minimum shear layer depth influence the modeling of the landslide dynamics. Hydrodynamic resistance forces, hydroplaning, and remolding are all crucial terms for underwater landslides, and are hence added into the numerical formulation. The landslide deformation is coupled to the water column and simulated in the Clawpack framework. For the propagation of the tsunamis, the shallow water equations and the Boussinesq-type equations are employed to observe how important the wave dispersion is. Finally, two cases in central Norway, i.e. the subaerial quick clay landslide at Byneset in 2012, and the submerged tsunamigenic Statland landslide in 2014, are both presented for validation. The research leading to these results has received funding from the Research Council of Norway under grant number 231252 (Project TsunamiLand) and the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement 603839 (Project ASTARTE).

  19. The influence of electronic cigarette age purchasing restrictions on adolescent tobacco and marijuana use.

    PubMed

    Pesko, Michael F; Hughes, Jenna M; Faisal, Fatima S

    2016-06-01

    In the United States, many states have established minimum legal purchase ages for electronic nicotine delivery systems (ENDS) to ban adolescent purchases, but these policies may also affect other related substance use. We explore whether ENDS are substitutes or complements for cigarettes, cigars, smokeless tobacco, and marijuana among adolescents by using variation in state-level implementation of ENDS age purchasing restrictions. We linked data on ENDS age purchasing restrictions to state- and year-specific rates of adolescent tobacco and marijuana use in 2007-2013 from the Youth Risk Behavior Surveillance System. This data provides a nationally representative sample of adolescents who attend public and private schools. We performed a fixed effect regression analysis exploring the influence of ENDS age purchasing restrictions on outcomes of tobacco use and marijuana use, controlling for state and year fixed characteristics, age-race cohorts, cigarette excise taxes, and cigarette indoor use restrictions. For cigarette use, we separate our results into cigarette use frequency. We found causal evidence that ENDS age purchasing restrictions increased adolescent regular cigarette use by 0.8 percentage points. ENDS age purchasing restrictions were not associated with cigar use, smokeless tobacco use, or marijuana use. We document a concerning trend of cigarette smoking among adolescents increasing when ENDS become more difficult to purchase. Copyright © 2016 Elsevier Inc. All rights reserved.

  20. Future Projections of Trans-Arctic Shipping Potential and Variability

    NASA Astrophysics Data System (ADS)

    Stephenson, S. R.; Smith, L. C.

    2014-12-01

    As the Arctic Ocean transitions towards a seasonally ice-free state, efforts to predict new connections between the Arctic and the global economy are underway. In particular, record lows in September sea ice extent from 2007-2013 have recast Arctic shipping routes as emerging international seaways for export of resources and as potential alternative pathways for global trade. While ensemble-averaged output from sea ice models suggest significant increases in vessel accessibility in September by midcentury (Smith & Stephenson, 2013), the seasonal length and variability of trans-Arctic shipping is not well understood. In addition, differences in ice extent due to inter-model variability reveal significant uncertainties in the magnitude and location of future vessel access. Here we present several scenarios of 21st-century trans-Arctic shipping as driven by sea ice output from CMIP5 models. Optimal vessel transits from North America and Europe to the Bering Strait are estimated for two periods representing present-day (2006-2015) and midcentury (2040-2059) conditions under two forcing scenarios (RCP 4.5/8.5), assuming Polar Class 6 (PC6) and open-water vessels (OW) with medium and no ice-breaking capability, respectively. Results illustrate a range of potential futures for shipping in the Arctic owing to differences in model choice, vessel capability, and climate forcing. Inter-model differences reveal the importance of model choice in devising projections for strategic planning by governments, environmental agencies, and the global maritime industry.

  1. A Review of Laboratory Experiments in Support of Interpretation of Hyperspectral Data from the Mars South Polar Residual Cap

    NASA Astrophysics Data System (ADS)

    Campbell, Jacqueline; Sidiropoulos, Panagiotis; Muller, Jan Peter

    2017-04-01

    The Martian South Polar Residual Cap (SPRC) is a permanent region of CO2 ice exhibiting unique, dynamic, flat floored, quasi-circular sublimation features known colloquially as Swiss Cheese Terrain (SCT). Sublimation processes can expose dust particles trapped within the ice during winter, which can be analysed using hyperspectral data from the Compact Reconnaissance Imaging Spectrometer for Mars (CRISM) on board NASA's Mars Reconnaissance Orbiter (MRO). Work is being carried out to establish the composition of these dust particles, and look for evidence of organic molecules that may have been afforded protection within the SPRC from the deleterious effects of ultraviolet radiation on the Martian surface. In this work we review laboratory experiments that have been carried out in order to better interpret CRISM spectra. In particular, SWIR (short-wave infrared) studies of CO2 and H2O ice/frost and dust mixtures, the behaviour of organic molecules in Martian conditions, and the angular reflectance measurements of such spectra. We will then briefly discuss what further work should be carried out to enable these measurements to be used to improve the interpretation of orbital hyperspectral data. Acknowledgements Part of the research leading to these results has received partial funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under iMars grant agreement n˚ 607379; MSSL STFC Consolidated grant no. ST/K000977/1 and the first author is supported by STFC under PhD studentship no. 526933.

  2. On the scaling features of high-latitude geomagnetic field fluctuations during a large geomagnetic storm

    NASA Astrophysics Data System (ADS)

    De Michelis, Paola; Federica Marcucci, Maria; Consolini, Giuseppe

    2015-04-01

    Recently we have investigated the spatial distribution of the scaling features of short-time scale magnetic field fluctuations using measurements from several ground-based geomagnetic observatories distributed in the northern hemisphere. We have found that the scaling features of fluctuations of the horizontal magnetic field component at time scales below 100 minutes are correlated with the geomagnetic activity level and with changes in the currents flowing in the ionosphere. Here, we present a detailed analysis of the dynamical changes of the magnetic field scaling features as a function of the geomagnetic activity level during the well-known large geomagnetic storm occurred on July, 15, 2000 (the Bastille event). The observed dynamical changes are discussed in relationship with the changes of the overall ionospheric polar convection and potential structure as reconstructed using SuperDARN data. This work is supported by the Italian National Program for Antarctic Research (PNRA) - Research Project 2013/AC3.08 and by the European Community's Seventh Framework Programme ([FP7/2007-2013]) under Grant no. 313038/STORM and

  3. An Integrated Nonlinear Analysis library - (INA) for solar system plasma turbulence

    NASA Astrophysics Data System (ADS)

    Munteanu, Costel; Kovacs, Peter; Echim, Marius; Koppan, Andras

    2014-05-01

    We present an integrated software library dedicated to the analysis of time series recorded in space and adapted to investigate turbulence, intermittency and multifractals. The library is written in MATLAB and provides a graphical user interface (GUI) customized for the analysis of space physics data available online like: Coordinated Data Analysis Web (CDAWeb), Automated Multi Dataset Analysis system (AMDA), Planetary Science Archive (PSA), World Data Center Kyoto (WDC), Ulysses Final Archive (UFA) and Cluster Active Archive (CAA). Three main modules are already implemented in INA : the Power Spectral Density (PSD) Analysis, the Wavelet and Intemittency Analysis and the Probability Density Functions (PDF) analysis.The layered structure of the software allows the user to easily switch between different modules/methods while retaining the same time interval for the analysis. The wavelet analysis module includes algorithms to compute and analyse the PSD, the Scalogram, the Local Intermittency Measure (LIM) or the Flatness parameter. The PDF analysis module includes algorithms for computing the PDFs for a range of scales and parameters fully customizable by the user; it also computes the Flatness parameter and enables fast comparison with standard PDF profiles like, for instance, the Gaussian PDF. The library has been already tested on Cluster and Venus Express data and we will show relevant examples. Research supported by the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement no 313038/STORM, and a grant of the Romanian Ministry of National Education, CNCS UEFISCDI, project number PN-II-ID PCE-2012-4-0418.

  4. Kinetic Energy of Tornadoes in the United States.

    PubMed

    Fricker, Tyler; Elsner, James B

    2015-01-01

    Tornadoes can cause catastrophic destruction. Here total kinetic energy (TKE) as a metric of destruction is computed from the fraction of the tornado path experiencing various damage levels and a characteristic wind speed for each level. The fraction of the path is obtained from a model developed for the Nuclear Regulatory Commission that combines theory with empirical data. TKE is validated as a useful metric by comparing it to other indexes and loss indicators. Half of all tornadoes have TKE exceeding 62.1 GJ and a quarter have TKE exceeding 383.2 GJ. One percent of the tornadoes have TKE exceeding 31.9 TJ. April has more energy than May with fewer tornadoes; March has more energy than June with half as many tornadoes. September has the least energy but November and December have the fewest tornadoes. Alabama ranks number one in terms of tornado energy with 2.48 PJ over the period 2007-2013. TKE can be used to help better understand the changing nature of tornado activity.

  5. The MyOcean Thematic Assembly Centres: Satellite and In-situ Observation Services in Review

    NASA Astrophysics Data System (ADS)

    Hackett, Bruce; Breivik, Lars-Anders; Larnicol, Gilles; Pouliquen, Sylvie; Santoleri, Rosalia; Roquet, Hervé; Stoffelen, Ad

    2015-04-01

    The MyOcean (2009-2012), MyOcean2 (2012-2014) and MyOcean Follow-On (October 2014 - March 2015) projects, respectively funded by the EU's 7th Framework Programme for Research (FP7 2007-2013) and HORIZON 2020 (EU Research and Innovation programme 2014-2020), have been designed to prepare and to lead the demonstration phases of the nascent European Copernicus Marine Environment Monitoring Service (CMS). The observational component of the MyOcean services is embodied in four Thematic Assembly Centres (TACs): Three provide satellite-based products for sea level (SL-TAC), for ocean colour (OC-TAC) and for surface temperature, winds and sea ice (OSI-TAC), while the fourth provides in-situ observations (INS-TAC). All the TAC production is developed from existing capabilities and there is close collaboration with related national and European data providers. Data products include near-real-time data and multi-year reprocessed datasets. Data formatting, dissemination methods and documentation follow uniform MyOcean standards for ease of use. The presentation will track the evolution of the TAC services through the MyOcean projects up to the opening of the CMS.

  6. Trends in motor neuron disease: association with latitude and air lead levels in Spain.

    PubMed

    Santurtún, Ana; Villar, Alejandro; Delgado-Alvarado, Manuel; Riancho, Javier

    2016-08-01

    Motor neuron diseases (MND) are a group of disorders characterized by motor neuron degeneration. Among them, amyotrophic lateral sclerosis (ALS) is by far the most common in adulthood. This paper assesses the trend and geographical pattern in MND incidence in Spain and the possible air lead levels effect on this pathology. To confirm this concept, we performed a retrospective analysis of the deaths due to MND in Spain during 2000 and 2013, determined the geographical differences, and explored the relationship between MND and the air levels of lead. Overall, between 2000 and 2013, 11,355 people died in Spain because of MND. Disease mortality significantly increased in recent years (2007-2013) when compared with the first time of the period. Spearman's rank correlation coefficient also showed a statistically significant positive trend (CC = 0.824, p = 0.0002). Among people over 65 years, mortality rates were higher in Northern provinces. Moreover, we found a significant association of MND mortality with higher air lead levels (CC = 0.457, p = 0.01). Our study confirms that MND mortality is increasing in Spain, with a significant latitude gradient, which suggests an important role of environmental exposures. This ecological study suggests that air lead levels may be implicated in ALS pathogenesis.

  7. Thirty years of European biotechnology programmes: from biomolecular engineering to the bioeconomy.

    PubMed

    Aguilar, Alfredo; Magnien, Etienne; Thomas, Daniel

    2013-06-25

    This article traces back thirty years of biotechnology research sponsored by the European Union (EU). It outlines the crucial role played by De Nettancourt, Goffeau and Van Hoeck to promote and prepare the first European programme on biotechnology (1982-1986) run by the European Commission. Following this first biotechnology programme, others followed until the current one, part of the seventh Framework Programme for Research, Technological Development and Demonstration (2007-2013) (FP7). Particular attention is given to the statutory role of the European institutions in the design and orientation of the successive biotechnology programmes, compared to the more informal-yet visionary-role of key individuals upstream to any legislative decision. Examples of success stories and of the role of the biotechnology programmes in addressing societal issues and industrial competitiveness are also presented. Finally, an outline of Horizon 2020, the successor of FP7, is described, together with the role of biotechnology in building the bioeconomy. Copyright © 2012 Elsevier B.V. All rights reserved.

  8. [Coercive procedures in forensic psychiatry : Current treatment practice in forensic psychiatric hospitals from a medical ethics perspective].

    PubMed

    Jakovljević, A-K; Wiesemann, C

    2016-07-01

    In 2011 the legal foundations of coercive treatment in German forensic psychiatric clinics were declared to be unconstitutional. In the present study we analyzed the frequency of coercive procedures in forensic psychiatric hospitals before and after 2011, the consequences for medical care as well as the ethical assessments by attending chief physicians. By a questionnaire-based survey of views of attending chief physicians in forensic psychiatric clinics in 2013, data on the current state of patient care were collected and analyzed from an ethical perspective. These were compared with treatment data from a large forensic psychiatric clinic collected over the period 2007-2013. Even after 2011 coercive forms of treatment were applied in forensic psychiatric hospitals. In practice, there is a high degree of legal uncertainty regarding the limits of coercive treatment. Of all patients treated in forensic psychiatric clinics in 2012, on average 13 % had been in isolation at least once, approximately 3 % had been treated under fixation at least once and 2.2 % had been subjected to coercive medical treatment at least once. From an ethical perspective an open debate about the practice of coercive treatment is urgently required. Legal regulations, ethical guidelines and treatment standards have to be developed for the special situation of patient care in forensic psychiatric hospitals.

  9. The Solar Corona and a CME at the 2010 Total Eclipse

    NASA Astrophysics Data System (ADS)

    Pasachoff, Jay M.; Rusin, V.; Druckmüllerová, H.; Saniga, M.; Lu, M.; Malamut, C.; Seaton, D. B.; Golub, L.; Engell, A. J.; Hill, S. W.; Lucas, R.

    2011-05-01

    The 11 July 2010 total solar eclipse was observed on the ground from French Polynesia and, 83 minutes later, from Easter Island, and near-simultaneous images were made with spacecraft instruments including AIA/SDO, HMI/SDO, EUVI/STEREO, SWAP/PROBA2, EIT/SOHO, and LASCO/SOHO. We report on changes in the corona detectable with high-resolution image processing of the ground-based eclipse coronal imaging, including two CME's that were seen to evolve. We compare with the spacecraft images to give a complete depiction of coronal structure at the time of the eclipse, which corresponded to a low but rising phase of the solar-activity cycle. We acknowledge the support of NASA's MSFC NNX10AK47A, NSF REU AST-1005024 with DoD ASSURE, VEGA 2/0098/10 of the Slovak Acad. Sci, 205/09/1469 of the Czech Science Foundation, PRODEX C90345 of ESA/BELSPO, FP7/2007-2013/218816 SOTERIA, Lockheed Martin; for equipment: Nikon Professional Services, ASTELCO Systems GmbH (Germany), and National Geographic Society's Photographic Division; and colleagues Y.-M. Wang (NRL), S. Habbal (U. Hawaii), H. Lanteires (Tatakoto), and J. Kern (Carnegie Obs.).

  10. Spectral characteristics of the Hellenic vertical network - Validation over Central and Northern Greece using GOCE/GRACE global geopotential models

    NASA Astrophysics Data System (ADS)

    Andritsanos, Vassilios D.; Vergos, George S.; Grigoriadis, Vassilios N.; Pagounis, Vassilios; Tziavos, Ilias N.

    2014-05-01

    The Elevation project, funded by the action "Archimedes III - Funding of research groups in T.E.I.", co-financed by the E.U. (European Social Fund) and national funds under the Operational Program "Education and Lifelong Learning 2007-2013" aims mainly to the validation of the Hellenic vertical datum. This validation is carried out over two areas under study, one in Central and another in Northern Greece. During the first stage of the validation process, satellite-only as well as combined satellite-terrestrial models of the Earth's geopotential are used. GOCE and GRACE satellite information is compared against recently measured GPS/Levelling observations at specific benchmarks of the vertical network in Attiki (Central Greece) and Thessaloniki (Northern Greece). A spectral enhancement approach is followed where, given the GOCE/GRACE GGM truncation degree, EGM2008 is used to fill-in the medium and high-frequency content along with RTM effects for the high and ultra high part. The second stage is based on the localization of possible blunders of the vertical network using the spectral information derived previously. The undoubted accuracy of the contemporary global models at the low frequency band leads to some initial conclusions about the consistency of the Hellenic vertical datum.

  11. High-resolution 2D3V simulations of forced hybrid-kinetic turbulence

    NASA Astrophysics Data System (ADS)

    Cerri, Silvio Sergio; Califano, Francesco; Rincon, Francois; Told, Daniel; Jenko, Frank; Pegoraro, Francesco

    2016-10-01

    The understanding of the kinetic processes at play in plasma turbulence is a frontier problem in plasma physics and among the topics currently of most interest in space plasma research. Here we investigate the properties of turbulence from the end of the magnetohydrodynamic (MHD) cascade to scales well below the ion gyroradius (i.e., the so-called ``dissipation'' or ``dispersion'' range) by means of unprecedented high-resolution simulations of forced hybrid-kinetic turbulence in a 2D3V phase-space (two real-space and three velocity-space dimensions). Different values of the plasma beta parameter typical of the solar wind (SW) are investigated. Several aspects of turbulence at small-scales emerging from the simulations are presented and discussed. Even within the limitations of the hybrid approach in 2D3V, a reasonable agreement with SW observations and with theory is found. Finally, we identify possible implications and questions related to SW turbulence which arise from this study. This research has been funded by European Union's Seventh Framework Programme (FP7/2007-2013)/ERC Grant Agreement No.277870 and by Euratom research and training programme 2014-2018. Simulations were performed on Fermi (CINECA, IT) and Hydra (MPCDF, DE).

  12. Dynamics of a vapor nanobubble collapsing near a solid boundary

    NASA Astrophysics Data System (ADS)

    Casciola, Carlo Massimo; Magaletti, Francesco; Gallo, Mirko; Sinibaldi, Giorgia; Marino, Luca

    2016-11-01

    The collapse of a nano-bubble near a solid wall is addressed exploiting a phase field model. The dynamics, triggered by a shock wave in the liquid, is explored for different conditions. It is characterized by a sequence of collapses and rebounds of the pure vapor bubble accompanied by the emission of shock waves in the liquid. The shocks are reflected by the wall to impinge back on the re-expanding bubble. The presence of the wall and the impinging shock wave break the symmetry of the system, leading, for sufficiently strong intensity of the incoming shock wave, to the poration of the bubble and the formation of an annular structure and a liquid jet Intense peaks of pressure and temperatures are found also at the wall, confirming that the strong localized loading combined with the jet impinging the wall is a potential source of substrate damage induced by the cavitation. Comparison of the numerical results with recent experiments on the collapse of a Laser induced cavitation bubble will also be discussed. The research leading to these results has received funding from the European Research Council under the European Union's Seventh Framework Programme (FP7/2007-2013)/ERC Project No. [339446], BIC - Following Bubbles from Inception to Cavitation.

  13. A workshop on enhanced national capability for neutron scattering

    SciTech Connect

    Hurd, Alan J; Rhyne, James J; Lewis, Paul S

    2009-01-01

    This two-day workshop will engage the international neutron scattering community to vet and improve the Lujan Center Strategic Plan 2007-2013 (SP07). Sponsored by the LANL SC Program Office and the University of California, the workshop will be hosted by LANSCE Professor Sunny Sinha (UCSD). Endorsement by the Spallation Neutron Source will be requested. The discussion will focus on the role that the Lujan Center will play in the national neutron scattering landscape assuming full utilization of beamlines, a refurbished LANSCE, and a 1.4-MW SNS. Because the Lujan Strategic Plan is intended to set the stage for the Signature Facility era at LANSCE, there will be some discussion of the long-pulse spallation source at Los Alamos. Breakout groups will cover several new instrument concepts, upgrades to present instruments, expanded sample environment capabilities, and a look to the future. The workshop is in keeping with a request by BES to update the Lujan strategic plan in coordination with the SNS and the broader neutron community. Workshop invitees will be drawn from the LANSCE User Group and a broad cross section of the US, European, and Pacific Rim neutron scattering research communities.

  14. Effects of latitude and weather conditions on proanthocyanidins in berries of Finnish wild and cultivated sea buckthorn (Hippophaë rhamnoides L. ssp. rhamnoides).

    PubMed

    Yang, Wei; Laaksonen, Oskar; Kallio, Heikki; Yang, Baoru

    2017-02-01

    Sea buckthorn (Hippophaë rhamnoides ssp. rhamnoides) of varieties 'Terhi' and 'Tytti' and one of wild origin were cultivated in southern and northern Finland, harvested during 2007-2013. Proanthocyanidins (PAs) were analyzed with HILIC UPLC-ESI-MS. The southern and northern samples were separated in the partial least squares discriminant analysis model (four factors, R(2) 0.75, Q(2) 0.70). The total PAs were more abundant in berries from the north (610-970mg/100gDW) than in those from the south (340-450mg/100gDW) (p<0.05). In northern Finland, the length of the growth season as well as the temperature sum and radiation sum of the growth season until harvest were negatively correlated with the total PAs in all the samples but positively with PA oligomers in 'Tytti' and 'Terhi'. In southern Finland no respective correlations were seen. 'Terhi' and 'Tytti' had different trends in the content of total PA and oligomers in overripe stages. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Improvement of total and tropospheric NO2 column retrieval for GOME-2

    NASA Astrophysics Data System (ADS)

    Liu, Song; Valks, Pieter; Pinardi, Gaia; De Smedt, Isabelle; Huan, Yu; Beirle, Steffen

    2016-04-01

    This contribution focuses on the development and refinement of novel scientific algorithms for the retrieval of total and tropospheric nitrogen dioxide (NO2) columns for the GOME-2 satellite instrument. NO2 plays significant roles in atmospheric chemistry. It is strongly related to ozone destruction in the stratosphere, and is regarded as an important air pollutant and ozone precursor in the troposphere. Total NO2 columns from GOME-2 are retrieved with the Differential Optical Absorption Spectroscopy (DOAS) method using the large 425-497 nm wavelength fitting window in order to increase the signal to noise ratio. The tropospheric NO2 column is derived using an improved Stratospheric-Tropospheric separation (STS) algorithm, followed by an air mass factor (AMF) conversion calculated with the LIDORT model. For the calculation of the tropospheric AMF, improved GOME-2 cloud parameters are used and a new surface albedo (LER) climatology based on GOME-2 observations for 2007-2013 is applied. We present the improvements in the NO2 retrieval algorithm, and we show examples of air quality applications with GOME-2 NO2 data.

  16. California current system - Predators and the preyscape

    NASA Astrophysics Data System (ADS)

    Ainley, David G.; Adams, Peter B.; Jahncke, Jaime

    2015-06-01

    The preyscape of the California Current System (CCS), one of the most productive marine areas on Earth (Glantz and Thompson, 1981), is highly variable, as evidenced by the papers in this issue, and as such presents a challenge to Ecosystem-based fishery management (EBFM), which attempts to integrate ecosystem considerations as part of fishery management and conservation decisions. Approaches to EBFM for the waters off Washington, Oregon, and California, the CCS, have been initiated (PFMC, 2007, 2013), and are continually being developed. To inform this process, a workshop was held in September 2013 to: i) gather together the existing information on forage fish and predator dynamics in the CCS; ii) consider temporal (seasonal, annual, decadal) and spatial availability of prey complexes and why these patterns of availability occur and change; iii) summarize and present that information for discussion to a large range of experts in oceanography, fish and fisheries management, seabirds, marine mammals, and ecosystem management; and, iv) synthesize this information to be useable by fishery agencies. The papers in this special Journal of Marine Systems issue address these four points. While the full results and recommendations can be found here - "http://www.pointblue.org/uploads/assets/calcurrent/REPORT_Forage_Fish_Workshop_FINAL.pdf"

  17. On the Topological Changes of Local Hurst Exponent in Polar Regions

    NASA Astrophysics Data System (ADS)

    Consolini, G.; De Michelis, P.

    2014-12-01

    Geomagnetic activity during magnetic substorms and storms is related to the dinamical and topological changes of the current systems flowing in the Earth's magnetosphere-ionosphere. This is particularly true in the case of polar regions where the enhancement of auroral electrojet current system is responsible for the observed geomagnetic perturbations. Here, using the DMA-technique we evaluate the local Hurst exponent (H"older exponent) for a set of 46 geomagnetic observatories, widely distributed in the northern hemisphere, during one of the most famous and strong geomagnetic storm, the Bastille event, and reconstruct a sequence of polar maps showing the dinamical changes of the topology of the local Hurst exponent with the geomagnetic activity level. The topological evolution of local Hurst exponent maps is discussed in relation to the dinamical changes of the current systems flowing in the polar ionosphere. G. Consolini has received funding from the European Community's Seventh Framework Programme (FP7/2007-2013) under Grant agreement no. 313038/STORM for this research.

  18. Detectability of penetration depth based on weld pool geometry and process emission spectrum in laser welding of copper

    NASA Astrophysics Data System (ADS)

    Özmert, Alp; Neisser-Deiters, Paul; Drenker, Alexander

    2014-05-01

    Laser welding is a promising joining process for copper interconnections. A key criterion of quality for these welds is the penetration depth. The penetration depth is subject to intrinsic variation, i.e. by the nature of the welding process. Online detection of penetration depth enables quality assurance and furthermore welding of joint configurations with tighter tolerances via closed-loop control. Weld pool geometry and keyhole optical emission in the wavelength interval of 400-1100 nm are investigated with regard to how suitable they are for the detection of penetration depth in laser welding of copper Cu-ETP. Different penetration depths were induced by stepwise modulation of laser power in bead-on-plate welds. The welds have been monitored with illuminated high-speed videography of the work piece surface and spectrometry. Increase of the weld pool length (in direction of travel) corresponding to increase in penetration depth has been observed while no noticeable change was observed of the weld pool width (transverse to the direction of travel). No significant lines were observed in the spectrum. The radiant power in VIS-spectrum was observed to increase with increasing penetration depth as well. As future work, with increasing understanding and experimental data, online monitoring by indirectly measuring the penetration depth would be possible. The research leading to these results has received funding from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement no 260153 (QCOALA: Quality Control for Aluminium Laser-Welded Assemblies).

  19. First Results on Visualization and Verification of the STEREO Heliospheric Imager CME Catalogue with In Situ Data from the Heliophysics System Observatory

    NASA Astrophysics Data System (ADS)

    Rollett, T.; Moestl, C.; Boakes, P. D.; Isavnin, A.; Davies, J. A.; Byrne, J.; Barnes, D.; Good, S. W.; Perry, C. H.; Kubicka, M.; Harrison, R. A.; Kilpua, E.; Forsyth, R. J.; Bothmer, V.

    2015-12-01

    The space weather community has recently seen major advances in the prediction of the speed and arrival time of solar coronal mass ejections at Earth and other planets. Since the start of the STEREO mission in 2006, each of the heliospheric imagers (HIs) onboard the Ahead and Behind spacecraft has successfully tracked hundreds of CMEs. The advantage of HI is that CMEs can be followed for a significant part of the inner heliosphere, and the CME evolution in direction and speed is better constrained than by coronagraphs alone. By tracking and cataloguing each of those CMEs in the EU HELCATS project, we can apply geometrical modeling (FPF, HMF, SSEF) techniques on single-spacecraft HI observations to extract the expected planetary impacts of each CME. These arrivals are then verified or refuted by in situ solar wind plasma and magnetic field observations provided by the spacecraft forming the Heliophysics System Observatory (HSO), such as Wind, ACE, Venus Express, MESSENGER, and STEREO-A/B, for which various ICME catalogues are gathered and updated in the course of HELCATS.A first assessment on the relationship between CME HI and in situ observations is discussed, such as occurrence rates, speeds and arrival times and magnetic field strength. We also present visualizations of the HI CME catalogue and the corresponding in situ observations. The presented work has received funding from the European Union Seventh Framework Programme (FP7/ 2007-2013) under grant agreement No. 606692 [HELCATS].

  20. Modeling of coronal mass ejections with the STEREO heliospheric imagers verified with in situ observations by the Heliophysics System Observatory

    NASA Astrophysics Data System (ADS)

    Möstl, Christian; Isavnin, Alexey; Kilpua, Emilia; Bothmer, Volker; Mrotzek, Nicolas; Boakes, Peter; Rodriguez, Luciano; Krupar, Vratislav; Eastwood, Jonathan; Davies, Jackie; Harrison, Richard; Barnes, David; Winslow, Reka; Helcats Team

    2017-04-01

    We present the first study to verify modeling of CMEs as observed by the heliospheric imagers on the two STEREO spacecraft with a large scale dataset of in situ plasma and magnetic field observations from the Heliophysics System Observatory, including MESSENGER, VEX, Wind, and the in situ measurements on the two STEREO spacecraft. To this end, we have established a new interplanetary CME catalog (ICMECAT) for these spacecraft by gathering and updating individual ICME lists. In addition, we have re-calculated the in situ parameters in a consistent way, resulting in 668 events observed between 2007-2015. We then calculated the efficacy of the STEREO/HI instruments for predicting (in hindsight) with the SSEF30 model the arrival time and speed of CMEs as well as hit/miss ratios. We also show how ICMECAT gives decent statistics concerning CME impacts on all of the terrestrial planets, including Mars. The results show some major implications for future heliospheric imagers which may be used for space weather forecasting. Our effort should also serve as a baseline for the upcoming new era in heliospheric science with Solar Orbiter, Solar Probe Plus, BepiColombo returning partly comparable observations in the next decade. The presented work has received funding from the European Union Seventh Framework Programme (FP7/ 2007-2013) under grant agreement No. 606692 [HELCATS].

  1. Twenty-five years of change in southern African passerine diversity: nonclimatic factors of change.

    PubMed

    Péron, Guillaume; Altwegg, Res

    2015-09-01

    We analysed more than 25 years of change in passerine bird distribution in South Africa, Swaziland and Lesotho, to show that species distributions can be influenced by processes that are at least in part independent of the local strength and direction of climate change: land use and ecological succession. We used occupancy models that separate species' detection from species' occupancy probability, fitted to citizen science data from both phases of the Southern African Bird Atlas Project (1987-1996 and 2007-2013). Temporal trends in species' occupancy probability were interpreted in terms of local extinction/colonization, and temporal trends in detection probability were interpreted in terms of change in abundance. We found for the first time at this scale that, as predicted in the context of bush encroachment, closed-savannah specialists increased where open-savannah specialists decreased. In addition, the trend in the abundance of species a priori thought to be favoured by agricultural conversion was negatively correlated with human population density, which is in line with hypotheses explaining the decline in farmland birds in the Northern Hemisphere. In addition to climate, vegetation cover and the intensity and time since agricultural conversion constitute important predictors of biodiversity changes in the region. Their inclusion will improve the reliability of predictive models of species distribution.

  2. L-Band Brightness Temperature Variations at Dome C and Snow Metamorphism at the Surface

    NASA Technical Reports Server (NTRS)

    Brucker, Ludovic; Dinnat, Emmanuel; Picard, Ghislain; Champollion, Nicolas

    2014-01-01

    The Antarctic Plateau is a promising site to monitor microwave radiometers' drift, and to inter-calibrate microwave radiometers, especially 1.4 GigaHertz (L-band) radiometers on board the Soil Moisture and Ocean Salinity (SMOS), and AquariusSAC-D missions. The Plateau is a thick ice cover, thermally stable in depth, with large dimensions, and relatively low heterogeneities. In addition, its high latitude location in the Southern Hemisphere enables frequent observations by polar-orbiting satellites, and no contaminations by radio frequency interference. At Dome C (75S, 123E), on the Antarctic Plateau, the substantial amount of in-situ snow measurements available allows us to interpret variations in space-borne microwave brightness temperature (TB) (e.g. Macelloni et al., 2007, 2013, Brucker et al., 2011, Champollion et al., 2013). However, to analyze the observations from the Aquarius radiometers, whose sensitivity is 0.15 K, the stability of the snow layers near the surface that are most susceptible to rapidly change needs to be precisely assessed. This study focuses on the spatial and temporal variations of the Aquarius TB over the Antarctic Plateau, and at Dome C in particular, to highlight the impact of snow surface metamorphism on the TB observations at L-band.

  3. Aquarius Brightness Temperature Variations at Dome C and Snow Metamorphism at the Surface. [29

    NASA Technical Reports Server (NTRS)

    Brucker, Ludovic; Dinnat, Emmanuel Phillippe; Picard, Ghislain; Champollion, Nicolas

    2014-01-01

    The Antarctic Plateau is a promising site to monitor microwave radiometers' drift, and to inter-calibrate microwave radiometers, especially 1.4 GHz (L-band) radiometers on board the Soil Moisture and Ocean Salinity (SMOS), and AquariusSAC-D missions. The Plateau is a thick ice cover, thermally stable in depth, with large dimensions, and relatively low heterogeneities. In addition, its high latitude location in the Southern Hemisphere enables frequent observations by polar-orbiting satellites, and no contaminations by radio frequency interference. At Dome C (75S, 123E), on the Antarctic Plateau, the substantial amount of in-situ snow measurements available allows us to interpret variations in space-borne microwave brightness temperature (TB) (e.g. Macelloni et al., 2007, 2013, Brucker et al., 2011, Champollion et al., 2013). However, to analyze the observations from the Aquarius radiometers, whose sensitivity is 0.15 K, the stability of the snow layers near the surface that are most susceptible to rapidly change needs to be precisely assessed. This study focuses on the spatial and temporal variations of the Aquarius TB over the Antarctic Plateau, and at Dome C in particular, to highlight the impact of snow surface metamorphism on the TB observations at L-band.

  4. Human factors and health information technology: current challenges and future directions.

    PubMed

    Patel, V L; Kannampallil, T G

    2014-08-15

    Recent federal mandates and incentives have spurred the rapid growth, development and adoption of health information technology (HIT). While providing significant benefits for better data integration, organization, and availability, recent reports have raised questions regarding their potential to cause medication errors, decreased clinician performance, and lowered efficiency. The goal of this survey article is to (a) examine the theoretical and foundational models of human factors and ergonomics (HFE) that are being advocated for achieving patient safety and quality, and their use in the evaluation of healthcare systems; (b) and the potential for macroergonomic HFE approaches within the context of current research in biomedical informatics. We reviewed literature (2007-2013) on the use of HFE approaches in healthcare settings, from databases such as Pubmed, CINAHL, and Cochran. Based on the review, we discuss the systems-oriented models, their use in the evaluation of HIT, and examples of their use in the evaluation of EHR systems, clinical workflow processes, and medication errors. We also discuss the opportunities for better integrating HFE methods within biomedical informatics research and its potential advantages. The use of HFE methods is still in its infancy - better integration of HFE within the design lifecycle, and quality improvement efforts can further the ability of informatics researchers to address the key concerns regarding the complexity in clinical settings and develop HIT solutions that are designed within the social fabric of the considered setting.

  5. Duration of syphilis symptoms at presentations in men who have sex with men in Australia: are current public health campaigns effective?

    PubMed

    Chow, E P F; Dutt, K; Fehler, G; Denham, I; Chen, M Y; Batrouney, C; Peel, J; Read, T R H; Bradshaw, C S; Fairley, C K

    2016-01-01

    The rapid rise in syphilis cases has prompted a number of public health campaigns to assist men who have sex with men (MSM) recognize and present early with symptoms. This study aimed to investigate the temporal trend of the duration of self-report symptoms and titre of rapid plasma reagin (RPR) in MSM with infectious syphilis. Seven hundred and sixty-one syphilis cases in MSM diagnosed at the Melbourne Sexual Health Centre (MSHC) from 2007-2013 were reviewed. Median duration of symptoms and RPR titres in each year were calculated. The median durations of symptoms with primary and secondary syphilis were 9 [interquartile range (IQR) 6-14] days and 14 (IQR 7-30) days, respectively. The overall median titre of RPR in secondary syphilis (median 128, IQR 64-256) was higher than in primary syphilis (median 4, IQR 1-32) and in early latent syphilis (median 32, IQR 4-64). The median duration of symptoms for primary syphilis, secondary syphilis and titre of RPR level did not change over time. Public health campaigns were not associated with a significant shorter time from onset of symptoms to treatment. Alternative strategies such as more frequent testing of MSM should be promoted to control the syphilis epidemic in Australia.

  6. The maximum drag reduction asymptote

    NASA Astrophysics Data System (ADS)

    Choueiri, George H.; Hof, Bjorn

    2015-11-01

    Addition of long chain polymers is one of the most efficient ways to reduce the drag of turbulent flows. Already very low concentration of polymers can lead to a substantial drag and upon further increase of the concentration the drag reduces until it reaches an empirically found limit, the so called maximum drag reduction (MDR) asymptote, which is independent of the type of polymer used. We here carry out a detailed experimental study of the approach to this asymptote for pipe flow. Particular attention is paid to the recently observed state of elasto-inertial turbulence (EIT) which has been reported to occur in polymer solutions at sufficiently high shear. Our results show that upon the approach to MDR Newtonian turbulence becomes marginalized (hibernation) and eventually completely disappears and is replaced by EIT. In particular, spectra of high Reynolds number MDR flows are compared to flows at high shear rates in small diameter tubes where EIT is found at Re < 100. The research leading to these results has received funding from the People Programme (Marie Curie Actions) of the European Union's Seventh Framework Programme (FP7/2007-2013) under REA grant agreement n° [291734].

  7. Slurm: An innovative Particle-in-Cell Method for Magnetohydrodynamics

    NASA Astrophysics Data System (ADS)

    Bacchini, Fabio; Olshevsky, Vyacheslav; Lapenta, Giovanni

    2016-10-01

    We present a new Particle-in-Cell method for plasma simulations. This is based on the original algorithm of FLIP-MHD, which uses a Lagrangian formulation of the macroscopic equations. A finite-difference approximation of the equations of motion is solved on a fixed (non-moving) grid, while convection of the quantities is modelled with the support of Lagrangian particles. Interpolation with first-order b-splines is used to project the conserved quantities from particles to the grid and back. In this work, we introduce two modifications of the original scheme. A particle volume evolution procedure is adopted to reduce the computational error, based on the Material Point Method for solid mechanics. The additional step introduces little to none computational diffusion and efficiently suppresses the so-called ringing instability, allowing the use of explicit time differencing. Furthermore, we eliminate the need for a Poisson solver in the magnetic field computation with the use of a vector potential. The vector potential evolution is modelled with a moving grid and interpolated to the fixed grid points to obtain a solenoidal magnetic field. The results of a number of HD and MHD tests show good agreement with the reference solutions and rather fast time and space convergence. Air Force Office of Scientific Research, Air Force Materiel Command, USAF under Award No. FA9550-14-1-0375. European Community's Seventh Framework Programme (FP7/2007-2013) via the DEEP-ER project under Grant Agreement No. 610476.

  8. Comparison of mercury concentrations measured at several sites in the Southern Hemisphere

    NASA Astrophysics Data System (ADS)

    Slemr, F.; Angot, H.; Dommergue, A.; Magand, O.; Barret, M.; Weigelt, A.; Ebinghaus, R.; Brunke, E.-G.; Pfaffhuber, K. A.; Edwards, G.; Howard, D.; Powell, J.; Keywood, M.; Wang, F.

    2015-03-01

    Our knowledge of the distribution of mercury concentrations in air of the Southern Hemisphere was until recently based mostly on intermittent measurements made during ship cruises. In the last few years continuous mercury monitoring has commenced at several sites in the Southern Hemisphere, providing new and more refined information. In this paper we compare mercury measurements at several remote sites in the Southern Hemisphere made over a period of at least 1 year at each location. Averages of monthly medians show similar although small seasonal variations at both Cape Point and Amsterdam Island. A pronounced seasonal variation at Troll research station in Antarctica is due to frequent mercury depletion events in the austral spring. Due to large scatter and large standard deviations of monthly average median mercury concentrations at Cape Grim, no systematic seasonal variation could be found there. Nevertheless, the annual average mercury concentrations at all sites during the 2007-2013 period varied only between 0.85 and 1.05 ng m-3. Part of this variability is likely due to systematic measurement uncertainties which we propose can be further reduced by improved calibration procedures. We conclude that mercury is much more uniformly distributed throughout the Southern Hemisphere than the distributions suggested by measurements made onboard ships. This finding implies that smaller trends can be detected in shorter time periods. We also report a change in the trend sign at Cape Point from decreasing mercury concentrations in 1996-2004 to increasing concentrations since 2007.

  9. New insights on short-term solar irradiance forecast for space weather applications

    NASA Astrophysics Data System (ADS)

    Vieira, L. A.; Dudok de Wit, T.; Balmaceda, L. A.; Dal Lago, A.; Da Silva, L. A.; Gonzalez, W. D.

    2013-12-01

    The conditions of the thermosphere, the ionosphere, the neutral atmosphere, and the oceans on time scales from days to millennia are highly dependent on the solar electromagnetic output, the solar irradiance. The development of physics-based solar irradiance models during the last decade improved significantly our understanding of the solar forcing on Earth's climate. These models are based on the assumption that most of the solar irradiance variability is related to the magnetic field structure of the Sun. Recently, these models were extended to allow short-term forecast (1 to 15 days) of the total and spectral solar irradiance. The extension of the irradiance models is based on solar surface magnetic flux models and/or artificial neural network models. Here, we discuss in details the irradiance forecast models based on observations of the solar surface magnetic field realized by the HMI instrument on board of SDO spacecraft. We constrained and validated the models by comparing the output of the models and observations of the solar irradiance made by instruments onboard The SORCE spacecraft. This study received funding from the European Community's Seventh Framework Programme (FP7/2007-2013, FP7-SPACE-2010-1) under the grant agreement nrs. 218816 (SOTERIA project, www.soteria-space.eu) and 261948 (ATMOP,www.atmop.eu), and by the CNPq/Brazil under the grant number 312488/2012-2. We also gratefully thank the instrument teams for making their data available.

  10. ULISSE -a new approach of archiving space experiment data

    NASA Astrophysics Data System (ADS)

    Brinckmann, Enno; Hauan, Tore Martin; Karoliussen, Irene; Fossum, Knut R.

    The evaluation of Space experiments is usually completed by a scientific publication. The re-maining sample material might be re-assessed by new techniques or with reference to other experiments, which might be difficult due to lacking of a common flight data archive. A new way of archiving Space experiment data has been initiated by the European Commission in the ULISSE Project ("USOCs KnowLedge Integration and dissemination for Space Science Experimentation") which is built around the User Support Operation Centers (USOCs) and their industrial partners. ULISSE will be a collaborative open network able to allow informa-tion and knowledge exchange. Due to the vast amount of data in this network, Web based interfaces need to be implemented. Therefore, each experiment will be described in a topic map containing experimental methods, the experiment environment, hardware and software methods and products, biological processes, and the experimental results. Each topic needs to have an identifier, i.e. a link to a Web based thesaurus where the definition of this topic is described. Existing databases (e.g. ontologies for genetic information) have been used to define recent Space experiments, but the range of topics needs to be extended in ULISSE to cover the specific features of Space experiments. Credits: European Commission (FP7/2007-2013, grant agreement n218815).

  11. Population Density, Poor Sanitation, and Enteric Infections in Nueva Santa Rosa, Guatemala.

    PubMed

    Jarquin, Claudia; Arnold, Benjamin F; Muñoz, Fredy; Lopez, Beatriz; Cuéllar, Victoria M; Thornton, Andrew; Patel, Jaymin; Reyes, Lisette; Roy, Sharon L; Bryan, Joe P; McCracken, John P; Colford, John M

    2016-04-01

    Poor sanitation could pose greater risk for enteric pathogen transmission at higher human population densities because of greater potential for pathogens to infect new hosts through environmentally mediated and person-to-person transmission. We hypothesized that incidence and prevalence of diarrhea, enteric protozoans, and soil-transmitted helminth infections would be higher in high-population-density areas compared with low-population-density areas, and that poor sanitation would pose greater risk for these enteric infections at high density compared with low density. We tested our hypotheses using 6 years of clinic-based diarrhea surveillance (2007-2013) including 4,360 geolocated diarrhea cases tested for 13 pathogens and a 2010 cross-sectional survey that measured environmental exposures from 204 households (920 people) and tested 701 stool specimens for enteric parasites. We found that population density was not a key determinant of enteric infection nor a strong effect modifier of risk posed by poor household sanitation in this setting.

  12. Dermoscopy of halo nevus in own observation.

    PubMed

    Kamińska-Winciorek, Grażyna; Szymszal, Jan

    2014-06-01

    Halo nevus (HN) is a rare dermatologic entity characterized by a typical whitish rim encircling the existing melanocytic nevus resembling a halo. The clinical picture is suggesting its diagnosis, but so far only several dermoscopic descriptions of halo nevus have existed in the PubMed database. To present the clinical and dermoscopic characteristics of halo nevus observed in dermoscopy. Fifteen patients were diagnosed clinically and dermoscopically with halo nevus during planned routine dermoscopic examinations of all melanocytic lesions in 2007-2013. All digital images stored in the computer database were analyzed retrospectively according to the procedure described in the study. The clinical and dermoscopic parameters such as the dermoscopic pattern, color of nevus, special features and description of the surrounding halo were analyzed statistically. We analyzed 22 halo nevi (9 in females, 13 in males) in 15 patients (7 females, 8 males) diagnosed during the dermoscopic examination. The mean age of patients during dermoscopic examinations was 18.2 years. Mean patients' age at HN onset was 15.7 years. Halo nevi occurred the most often as a solitary lesion. The ratio of multiple halo nevi to solitary halo nevus was 5 : 10. Every third halo nevus was located on the posterior trunk upper. In 68.2% of HN cases, the surrounding rim (halo) was characterized by its homogenous, whitish color. Dermoscopic patterns such as uniform globular and structureless constituted one-third each of them in all analyzed patterns.

  13. Overcoming Interoperability Weaknesses in e-Government Processes: Organizing and Sharing Knowledge in Regional Development Programs Using Ontologies

    NASA Astrophysics Data System (ADS)

    Scorza, Francesco; Casas, Giuseppe Las; Murgante, Beniamino

    European Regional Policy produced several generations of programmes at both National and Regional levels. Such a complex framework tends to increase multi-level governance in the period 2007-2013, promoting a wider participation of stakeholders (including Public Administration, Local Communities, Enterprises, etc). This process has been usually accompanied by e-tools for the management of bottom-up processes, with several instances related to common problems of participation processes. Communication between "programmer" and categories of beneficiaries always presented weakness due to the ineffective system of management knowledge within the process. Relevant issues in the framework of regional development programmes are: Do stakeholders understand the meaning of general and sectoral policies? Are citizens aware of technical instruments implementing such policies? Are they conscious of ex-ante comprehensive context analysis and/or can they share possible future scenarios? A way to tackle these problems is the use of ontologies. In this work we present the structural elements of the ontology of regional development programmes analyzing major steps of the ontology design and nodal phases of the ontology building (i.e. consensus on relations and restrictions, switch from glossary to taxonomy). The result of such an application is an ontology of regional development containing more than one hundred classes.

  14. The Association Between Blood Mercury Levels and Risk for Overweight in a General Adult Population: Results from the Korean National Health and Nutrition Examination Survey.

    PubMed

    Lee, Seunghyun; Yoon, Jin-Ha; Won, Jong-Uk; Lee, Wanhyung; Lee, June-Hee; Seok, Hongdeok; Kim, Yeong-Kwang; Kim, Chi-Nyon; Roh, Jaehoon

    2016-06-01

    The primary objective of this study was to estimate the association between blood mercury levels and overweight in Korean adults. We analyzed cross-sectional data from 9228 participants (4283 men and 4945 women) who completed the Korean National Health and Nutrition Examination Survey (KNHANES), 2007-2013. The population was divided into two groups according to the body mass index (BMI) and waist circumference (WC). Blood mercury levels were analyzed using a gold amalgam method with a DMA-80 instrument, categorized into quartiles, and stratified by sex. After adjusting for all covariates, blood mercury was significantly associated with overweight in all subjects. According to the BMI criteria, the adjusted odds ratio of being in the highest blood mercury quartile was 1.75 (95 % confidence interval [CI], 1.53-2.01) overall, 2.09 (95 % CI, 1.71-2.55) in men, and 1.58 (95 % CI, 1.32-1.89) in women. According to the WC criteria, the adjusted odds ratio of being in the highest blood mercury quartile was 1.85 (95 % CI, 1.49-2.30) in men and 1.96 (95 % CI, 1.62-2.36) in women compared to the lowest quartile. Additionally, a trend in overweight across increasing blood mercury levels was observed by the p for trend test in the multiple diagnostic criteria.

  15. Cadmium, lead, mercury and arsenic in animal feed and feed materials - trend analysis of monitoring results.

    PubMed

    Adamse, Paulien; Van der Fels-Klerx, H J Ine; de Jong, Jacob

    2017-03-02

    This study aimed to obtain insights into the presence of cadmium, lead, mercury and arsenic in feed materials and feed over time, for the purpose of guiding national monitoring. Data from the Dutch feed monitoring program and from representatives of the feed industry in the period 2007-2013 were used. Data covered the concentrations of cadmium, lead, mercury and arsenic in a variety of feed materials and compound feeds in The Netherlands. Trends in the percentage of samples that exceeded the maximum limit (ML), set by the European Commission, and trends in average, median and 90(th) percentile concentrations of each of these elements per feed material or compound feed were investigated. Based on the results, monitoring for cadmium, lead, mercury and arsenic should focus on feed material of mineral origin, feed material of marine origin, especially fish meal, seaweed and algae as well as feed additives belonging to the functional groups of (i) trace elements (notably cupric sulphate, zinc oxide and manganese oxide for arsenic) and (ii) binders and anti-caking agents. Mycotoxin binders are a new group of feed additives that also need attention. For complementary feed it is important to make a proper distinction between mineral and non-mineral feed because the ML in the latter group is usually lower. In seaweed/algae products a relatively large number of samples contained arsenic concentrations that exceeded the ML. Forage crops in general do not need high priority in monitoring programs, although for arsenic grass meal still needs attention.

  16. Global S4 Index Maximum Probed by FORMOSAT-3 /COSMIC

    NASA Astrophysics Data System (ADS)

    Liu, Jann-Yenq; Chen, Shih-Ping; Yeh, Wen-Hao; Liu, Chao-Han

    2014-05-01

    This paper reports 3D structure and dynamics of the ionospheric scintillation in terms of the maximum value of the S4 index (S4max) probed by radio occultation FORMOSAT-3/COSMIC (F3/C) satellites during 2007-2013. The S4 index is calculated from fluctuations of the signal-to-noise ratio (SNR) intensity in the L1 channel of GPS radio occultation signals recorded by F3/C GOX (Gps Occultation eXperiment). On average, nearly 6000 to 7000 S4 index profiles are derived by F3/C per day covering an altitude range from the Earth's surface to 800 km. The diurnal, seasonal, solar activity, and geographical variations of 3D S4max are examined. An integral process is introduced converting the satellite-based S4max to ground-based one which will be further used to estimate the worst case of GPS scintillation on the ground during both low and high solar activities.

  17. An improved model to analyze Langmuir probe assisted photo-detachment signal for measuring electronegative plasma parameters

    NASA Astrophysics Data System (ADS)

    Sirse, Nishant; Oudini, Noureddine; Bendib, Abderrezeg; Ellingboe, Albert R.

    2016-09-01

    A diagnostic technique for measuring negative ion parameters based on Langmuir probe assisted laser photo-detachment relies on a theoretical model which relates the rise in the electron saturation current to electronegativity in the plasma. The existing model depend on various assumptions and neglect electrostatic potential barrier formed between the laser column (electropositive column) and the surrounding electronegative plasma in order to prevent the outward flow of electrons from the electropositive plasma column. These assumptions leads to erroneous estimation of the plasma electronegativity. In the present work, we present an analytical model to analyze Langmuir probe assisted photo-detachment signal in order to improve the accuracy of measured electronegativity and extended this technique for measuring electron temperature and charged species density. The analytical model is validated using both experiments and particle-in-cell simulation. The results shows improved accuracy in the measured parameters when compared to existing model. This work was supported by the Korea Institute for the Advancement of Technology and Ministry of Knowledge Economy (L-2010-1438-000), Republic of Korea, Enterprise Ireland and the European Regional Development Fund (ERDF) under NSRF 2007-2013.

  18. 2-d chemical sampling of a tropopause fold over the Mediterranean: Observations by the IR limb-imager GLORIA and calculations by chemistry-transport models

    NASA Astrophysics Data System (ADS)

    Johansson, Sören; Friedl-Vallon, Felix; Höpfner, Michael; Ungermann, Jörn; Vogel, Bärbel; Grooß, Jens-Uwe; Müller, Rolf; Diekmann, Christopher; Schröter, Jennifer; Ruhnke, Roland; Orphal, Johannes

    2017-04-01

    We will present results from measurements obtained by the GLORIA (Gimballed Limb Observer for Radiance Imaging of the Atmosphere) instrument that has been operated on the Geophysica research aircraft during a field campaign within the European StratoClim project in the Mediterranean area with basis in Kalamata, Greece, in September 2016. The flight at an altitude of 18 km (400 K) reached the eastern Mediterranean south of Cyprus, where air influence by the Asian Monsoon was sampled. We will show retrievals of two-dimensional trace-gas distributions derived from GLORIA observations performed with high spectral resolution. Targeted gases are, amongst others, O3 and HNO3 as stratospheric tracers and PAN and C2H6 as pollution indicators. We will present an analysis of retrieval performance including diagnostics of spatial resolution and an estimated error budget. For a first scientific analysis, comparisons to atmospheric model simulations from two atmospheric chemistry-transport models, ICON-ART (ICOsahedral Nonhydrostatic model - Aerosols and Reactive Trace gases) and CLaMS (Chemical Lagrangian Model of the Stratosphere) will be discussed. Focus will be on comparisons of the distribution of the trace gases measured by GLORIA to the model tracers indicating the chemical composition as well as well as the air mass origin. Acknowledgements: The research leading to these results has received funding from the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement n° 603557

  19. European Union investment and countries' involvement in mental health research between 2007 and 2013.

    PubMed

    Hazo, J-B; Gervaix, J; Gandré, C; Brunn, M; Leboyer, M; Chevreul, K

    2016-08-01

    This study aimed to estimate the commitment to mental health research by the European Union (EU) through the 7th framework (FP7) and the competitiveness and innovation (CIP) programmes during the 2007-2013 period. Research projects dedicated or partially related to mental health were identified using keywords in the CORDIS database that inventories all FP7 and CIP research projects. We then contacted projects' principal investigators to access the budget breakdown by country and performed an imputation of the distribution of funding between countries based on projects' and participants' characteristics where information was missing. Among the 25 783 research projects funded by the FP7 and the CIP, 215 (0.8%) were specifically dedicated to mental health and 170 (0.7%) were partially related to mental health. They received €607.1 million representing 1.4% of FP7 total funding. Within the FP7-Health subprogramme, the projects represented 5.2% of funding. Important variations appeared across EU countries both for raw funding, which varied between €0 and €77M, and for funding per 100 inhabitants, which varied between €0 and €293. EU funding of mental health research does not match the burden incurred by mental disorders and must be increased in the next framework programme. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  20. Human and canine visceral leishmaniasis in an emerging focus in Araçuaí, Minas Gerais: spatial distribution and socio-environmental factors

    PubMed Central

    Ursine, Renata Luiz; Dias, João Victor Leite; Morais, Harriman Aley; Pires, Herton Helder Rocha

    2016-01-01

    This study aimed to analyse the spatial distribution of human (2007-2013) and canine (2013) visceral leishmaniasis (VL) in the city of Araçuaí, Minas Gerais, Brazil, and identify the socio-environmental factors related to their occurrence. The spatial distribution of human and canine cases was analysed by kernel density estimation (KDE) and the K function. The KDE values were analysed for correlation between human and canine LV and for normalised difference vegetation index (NDVI). Socio-environmental aspects of household structures and surroundings were evaluated. The spatial distribution of human and canine VL cases exhibited a significant aggregated pattern in distances greater than 350 and 75 m, respectively. The higher occurrence of human and canine infection occurred in the central area of the city. A positive correlation between the densities of human and canine cases was observed, as well as a negative correlation between NDVI and densities of human and canine cases. Socio-environmental analysis revealed that the large amount of animals, organic material from trees and deficiencies in environmental sanitation are possibly contributing to the continuation of the transmission cycle of Leishmania infantum in Araçuaí. These results can contribute to the planning by competent agencies to reduce the incidence of infection in the city. PMID:27384080

  1. On the basis size problem in ultracold molecular scattering: Approximate hyperfine cross sections from hyperfine-free calculations

    NASA Astrophysics Data System (ADS)

    Gonzalez-Martinez, Maykel Leonardo

    2014-05-01

    Understanding (ultra)cold collisions is crucial to assess both the prospects of cooling techniques that rely on thermalization and trapping lifetimes. However, brute-force application of the coupled-channel method to many low-temperature scattering problems finds two main obstacles: (1) the need for large basis sets that are computationally intractable, and (2) the need to explore a multidimensional parametric space in order to tackle questions concerning real experimental conditions. The basis size problem arises because many interactions that are negligible at thermal temperatures become comparable to, or larger than, the collision energies involved. Taking all such terms into account significantly increases the size of the basis needed for convergence, with dramatic effects on the computing effort. Here, I discuss an approximate method to account for the effect of hyperfine interactions in ultracold molecular scattering. The method naturally resolves the effects discussed by Gonzalez-Martinez and Hutson in calculations on Mg+NH, and may be combined with those by Tscherbul et al. and Croft et al. to tackle problems which are computationally intractable to date. Depending on the system, the proposed method may lead to one to four orders-of-magnitude savings in computing times. This work was partially supported by EPSRC, and by FP7/2007-2013 under grant No. 330623.

  2. Effectiveness of a Core-Competency-based Program on Residents' Learning and Experience.

    PubMed

    Charles, Lesley; Triscott, Jean; Dobbs, Bonnie; Tian, Peter George; Babenko, Oksana

    2016-06-01

    The Care of the Elderly (COE) Diploma Program is a six-to-twelve-month enhanced skills program taken after two years of core residency training in Family Medicine. In 2010, we developed and implemented a core-competency-based COE Diploma program (CC), in lieu of one based on learning objectives (LO). This study assessed the effectiveness of the core-competency-based program on residents' learning and their training experience as compared to residents trained using learning objectives. The data from the 2007-2013 COE residents were used in the study, with nine and eight residents trained in the LO and CC programs, respectively. Residents' learning was measured using preceptors' evaluations of residents' skills/abilities throughout the program (118 evaluations in total). Residents' rating of training experience was measured using the Graduate's Questionnaire which residents completed after graduation. For residents' learning, overall, there was no significant difference between the two programs. However, when examined as a function of the four CanMEDS roles, there were significant increases in the CC residents' scores for two of the CanMEDS roles: Communicator/Collaborator/Manager and Scholar compared to residents in the LO program. With respect to residents' training experience, seven out of ten program components were rated by the CC residents higher than by the LO residents. The implementation of a COE CC program appears to facilitate resident learning and training experience.

  3. Human Factors and Health Information Technology: Current Challenges and Future Directions

    PubMed Central

    Kannampallil, T. G.

    2014-01-01

    Summary Objectives Recent federal mandates and incentives have spurred the rapid growth, development and adoption of health information technology (HIT). While providing significant benefits for better data integration, organization, and availability, recent reports have raised questions regarding their potential to cause medication errors, decreased clinician performance, and lowered efficiency. The goal of this survey article is to (a) examine the theoretical and foundational models of human factors and ergonomics (HFE) that are being advocated for achieving patient safety and quality, and their use in the evaluation of healthcare systems; (b) and the potential for macroergonomic HFE approaches within the context of current research in biomedical informatics. Methods We reviewed literature (2007-2013) on the use of HFE approaches in healthcare settings, from databases such as Pubmed, CINAHL, and Cochran. Results Based on the review, we discuss the systems-oriented models, their use in the evaluation of HIT, and examples of their use in the evaluation of EHR systems, clinical workflow processes, and medication errors. We also discuss the opportunities for better integrating HFE methods within biomedical informatics research and its potential advantages. Conclusions The use of HFE methods is still in its infancy - better integration of HFE within the design lifecycle, and quality improvement efforts can further the ability of informatics researchers to address the key concerns regarding the complexity in clinical settings and develop HIT solutions that are designed within the social fabric of the considered setting. PMID:25123724

  4. [Allogeneic hematopoietic stem cell transplantation in Hungary].

    PubMed

    Bátai, Árpád; Reményi, Péter; Réti, Marienn; Barta, Anikó; Gopcsa, László; Lengyel, Lilla; Torbágyi, Éva; Csukly, Zoltán; Karászi, Éva; Tordai, Attila; Andrikovics, Hajnalka; Balassa, Katalin; Tasnády, Szabolcs; Masszi, Tamás

    2017-02-01

    The publication summarizes the 2548 stem cell transplantations performed in the period of 1993-2015 in Szent Laszló Hospital, Budapest and provides a detailed discussion of the 425 allogeneic transplantations during 2007-2013. The analysis explains the major steps of the evolution of allogeneic stem cell transplantation and compares the results of the unique Hungarian allogeneic center. The significant shift in the transplantation indications from chronic myeloid leukemia to myelodysplastic syndromes and the rising age of the recipients are in line with world wide tendencies. The latter one is the consequence of the introduction and improvement of the concept of reduced intensity conditioning regimens, originally arising from the idea of Endre Kelemen. The most limiting factor, the donor availability seems to be resolved with the use of a new immunomodulating regimen, the application of posttransplantation cyclophosphamide, which allows the transplantation through HLA barriers with haploidentical family donors with comparable results to the HLA matched volunteer unrelated donors. The above mentioned tendencies result the wider use of allogeneic stem cell transplantation less dependent from recipient age, comorbidities and even donor availability. The publication highlights the need of expanding the stem cell transplantation budget and the involvement of new centers in Hungary in allogeneic of stem cell transplantation. Orv. Hetil., 2017, 158(8), 291-297.

  5. Detection of fog layers characteristics with ground-based remote sensing equipments

    NASA Astrophysics Data System (ADS)

    Toanca, Florica; Stefan, Sabina; Binietoglou, Ioannis; Labzovskii, Lev; Stefanie, Horatiu

    2015-04-01

    Fog is one of the phenomena that generates important economic problems and also impacts a broad variety of human activities. This study aims to determine fog layers characteristics in terms of type, time evolution, and vertical extent in Magurele, Romania (44.35 N, 26.03 E) for two periods (2012 and 2013). Data regarding fog evolution was provided by a Vaisala CL31 Ceilometer and a HATPRO Microwave Radiometer. Ceilometer profiles are obtained with a time resolution of 16 s and up to 7.5 km altitude. Microwave radiometer uses passive microwave detection in the 22.335 to 31.4 GHz and 51 to 58 GHz bands to obtain the vertical profiles of temperature and relative humidity up to 10 km with a temporal resolution of several minutes. MWR also provide integrated water vapor and liquid water path. Considering all this information from active and passive remote sensing instruments, we present preliminary results towards a method for fog type classification. The extended database containing fog measurements for a two years period is used in a statistical analysis of the evolution and geometrical properties for each fog type. Acknowledgements The work was supported by the strategic grant POSDRU/159/1.5/S/137750, "Project Doctoral and Postdoctoral programs support for increased competitiveness in Exact Sciences research" co financed by the European Social Found within the Sectorial Operational Program Human Resources Development 2007-2013 and by a grant of the STAR-ESA Programme 39/2012-SIAFIM.

  6. Local magnitude calibration of the Hellenic Unified Seismic Network

    NASA Astrophysics Data System (ADS)

    Scordilis, E. M.; Kementzetzidou, D.; Papazachos, B. C.

    2016-01-01

    A new relation is proposed for accurate determination of local magnitudes in Greece. This relation is based on a large number of synthetic Wood-Anderson (SWA) seismograms corresponding to 782 regional shallow earthquakes which occurred during the period 2007-2013 and recorded by 98 digital broad-band stations. These stations are installed and operated by the following: (a) the National Observatory of Athens (HL), (b) the Department of Geophysics of the Aristotle University of Thessaloniki (HT), (c) the Seismological Laboratory of the University of Athens (HA), and (d) the Seismological Laboratory of the Patras University (HP). The seismological networks of the above institutions constitute the recently (2004) established Hellenic Unified Seismic Network (HUSN). These records are used to calculate a refined geometrical spreading factor and an anelastic attenuation coefficient, representative for Greece and surrounding areas, proper for accurate calculation of local magnitudes in this region. Individual station corrections depending on the crustal structure variations in their vicinity and possible inconsistencies in instruments responses are also considered in order to further ameliorate magnitude estimation accuracy. Comparison of such calculated local magnitudes with corresponding original moment magnitudes, based on an independent dataset, revealed that these magnitude scales are equivalent for a wide range of values.

  7. Publication outcomes for research presented at a Canadian surgical conference.

    PubMed

    Crawford, Sean A; Roche-Nagle, Graham

    2017-04-01

    The failure of investigators to publish research in peer-reviewed journals following acceptance at a national or international meeting can lead to significant publication biases in the literature. Our objective was to evaluate the abstract to manuscript conversion rate for abstracts presented at the Canadian Society for Vascular Surgery (CSVS) annual meeting and to evaluate the conversion rate for CSVS-awarded research grants. We searched for authors of abstracts accepted at the CSVS Annual Meeting (2007-2013) and recipients of CSVS research awards (2005-2013) on Scopus and PubMed databases to identify related publications. We identified 84 publications from 188 research abstracts (45%) and 17 publications from 39 research grants (44%). The mean time to publication was 1.8 years and the mean impact factor was 2.7. Studies related to endovascular therapies demonstrated a trend toward a higher rate of publication relative to open surgical therapies (64 [56%] v. 37 [27%]). Additionally, we observed a similar trend in research grant topics related to endovascular therapies relative to open surgical therapies (9 [67%] v. 8 [38%]). Finally, CSVS research grant recipients who subsequently published had a significantly higher h-index at the time of receipt than those who had not published. The CSVS annual meeting's abstract to publication conversion rate is comparable to that of its Canadian peers as well as to other medical specialties; however, a substantial publication gap remains. We identified several potential areas that may help to improve the effectiveness of CSVS research grants.

  8. Assessing the progress in depolluting the Mediterranean Sea.

    PubMed

    Spiteri, Claudette; Roddier-Quefelec, Cécile; Giraud, Jean-Pierre; Hema, Tatiana

    2016-01-30

    The depollution of the Mediterranean Sea by 2020 is the overarching goal of Horizon 2020 Initiative (H2020). The first phase (2007-2013) tackled the main land-based pollution sources; municipal waste, urban wastewater and industrial emissions. As part of the H2020 roadmap implementation, the ENPI-SEIS project focused on the first H2020 review mechanism that included a) establishing a process for regular environmental reporting in the European Neighbourhood Policy South countries, and b) generating the knowledge necessary to assess the progress in depolluting the Mediterranean Sea. This paper reviews the process in line with the "Shared Environmental Information System" principles and its three pillars (content, cooperation, infrastructure). The main outcomes of the thematic assessment, based on a set of regional H2020 indicators, are also presented. This assessment highlights the major drivers and their implications on marine protection. It also identifies areas that require further attention in the next phase of H2020 (2014-2020). Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. Validation of a New Method to Derive Sun-to-1 AU Kinematics of ICMEs with a Numerical Simulation

    NASA Astrophysics Data System (ADS)

    Rollett, T.; Moestl, C.; Lugaz, N.; Temmer, M.; Veronig, A. M.

    2011-12-01

    The Heliospheric Imagers (HI) aboard the NASA STEREO mission offer the possibility to follow coronal mass ejections (CMEs) continuously on their way from close to the Sun up to ~ 1 AU. The interpretation of these images is challenging because line-of-sight as well as Thomson scattering effects influence the white-light signal. There are different methods to derive the velocity profiles and propagation directions of CMEs in the interplanetary space, e.g. Fixed-Φ (Kahler and Webb, 2007) and Harmonic Mean (Lugaz, Vourlidas and Roussev, 2009), which make the assumptions of a point like structure and a circle shaped front of the CME, respectively. These two approaches can be constrained using in situ measurements at 1 AU as shown in Rollett et al. (2011). To validate the applied methods, we perform the same procedures for a simulated CME as modeled in the space weather modeling framework (SWMF, Toth, et al., 2005). The measurements are outlined for synthetic HI images (Lugaz et al., 2005) at different observing points. The research leading to these results has received funding from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement no. 263252 [COMESEP].

  10. European research infrastructures for the development of nanobiotechnologies.

    PubMed

    Péro, Hervé; Faure, Jean-Emmanuel

    2007-05-01

    Research infrastructures are essential for top-level academic and industrial research activities. Throughout the successive framework programmes (FPs) of the EU, actions have been gradually developed to support researchers in accessing top-level European research infrastructures located outside their own country and also to better coordinate and integrate these infrastructures Europe-wide, enabling better research services. At the same time, research infrastructures pave the way for the development of scientific and technological advances. Under the sixth Framework Programme (FP6; 2002-2006), for example, nanobiotechnologies have benefited from these European actions through three approaches: the support of multi-disciplinary pan-European infrastructures; the support of pan-European infrastructures dedicated to biology but with usage in multiple domains of biology; and the funding of integrated centers for nanobiotechnologies. The seventh Framework Programme (FP7; 2007-2013) will reinforce these actions toward research infrastructures, with particular attention to the emergence of new ones as well as to the provision of important strategic research services in fields such as nanobiotechnologies.

  11. Experience from a single paediatric transplant centre with identification of some protective and risk factors concerning the development of hepatic veno-occlusive disease in children after allogeneic hematopoietic stem cell transplant.

    PubMed

    Maximova, N; Ferrara, G; Minute, M; Pizzol, A; Kiren, V; Montico, M; Gregori, M; Tamaro, P

    2014-06-01

    Hepatic veno-occlusive disease (VOD) is a frequent and severe complication of hematopoietic stem cell transplantation (HSCT) affecting 9.6-17.3 % of cases. 200 HSCT, performed between January 1995 and March 2013 in our Paediatric HSCT Centre in Trieste, were retrospectively analysed to evaluate the frequency of VOD and to identify the associated risk factors. The frequency of VOD according to the Seattle criteria was 17 %, within the range reported in literature. The mortality rate was 37.5 % (75 out of 200 transplantations) in the general population and 73.5 % (25 out of 34) in VOD patients (p < 0.05). Veno-occlusive disease significantly decreased from 38 % (1995-2000) to 8 % (2007-2013) p < 0.05. Univariate and multivariate analyses identified sepsis and pre-transplant ferritin levels above 1000 ng/ml as two significant risk factors for VOD, while the use of tacrolimus appeared to be associated with a lower VOD risk. Veno-occlusive disease still remains an important cause of transplant-related mortality even if it appears to have decreased over the last few years.

  12. Dynamic systems and the role of evaluation: The case of the Green Communities project.

    PubMed

    Anzoise, Valentina; Sardo, Stefania

    2016-02-01

    The crucial role evaluation can play in the co-development of project design and its implementation will be addressed through the analysis of a case study, the Green Communities (GC) project, funded by the Italian Ministry of Environment within the EU Interregional Operational Program (2007-2013) "Renewable Energy and Energy Efficiency". The project's broader goals included an attempt to trigger a change in Italian local development strategies, especially for mountain and inland areas, which would be tailored to the real needs of communities, and based on a sustainable exploitation and management of the territorial assets. The goal was not achieved, and this paper addresses the issues of how GC could have been more effective in fostering a vision of change, and which design adaptations and evaluation procedures would have allowed the project to better cope with the unexpected consequences and resistances it encountered. The conclusions drawn are that projects should be conceived, designed and carried out as dynamic systems, inclusive of a dynamic and engaged evaluation enabling the generation of feedbacks loops, iteratively interpreting the narratives and dynamics unfolding within the project, and actively monitoring the potential of various relationships among project participants for generating positive social change.

  13. Night-sky brightness and extinction at Mt Shatdzhatmaz

    NASA Astrophysics Data System (ADS)

    Kornilov, V.; Kornilov, M.; Voziakova, O.; Shatsky, N.; Safonov, B.; Gorbunov, I.; Potanin, S.; Cheryasov, D.; Senik, V.

    2016-11-01

    The photometric sky quality of Mt Shatdzhatmaz, the site of the Sternberg Astronomical Institute Caucasian Observatory 2.5-m telescope, is characterized here by the statistics of the night-time sky brightness and extinction. The data were obtained as a by-product of atmospheric optical turbulence measurements with the MASS (Multi-Aperture Scintillation Sensor) device conducted in 2007-2013. The factors biasing night-sky brightness measurements are considered and a technique to reduce their impact on the statistics is proposed. The single-band photometric estimations provided by MASS are easy to transform to the standard photometric bands. The median moonless night-sky brightness is 22.1, 21.1, 20.3 and 19.0 mag arcsec-2 for the B, V, R and I spectral bands, respectively. The median extinction coefficients for the same photometric bands are 0.28, 0.17, 0.13 and 0.09 mag. The best atmospheric transparency is observed in winter.

  14. Coupled versus decoupled multigrid solvers for variable viscosity Stokes problems using a staggered finite difference scheme.

    NASA Astrophysics Data System (ADS)

    Kaus, Boris; Popov, Anton; Püsök, Adina

    2014-05-01

    In order to solve high-resolution 3D problems in computational geodynamics it is crucial to use multigrid solvers in combination with parallel computers. A number of approaches are currently in use in the community, which can broadly be divided into coupled and decoupled approaches. In the decoupled approach, an algebraic or geometric multigrid method is used as a preconditioner for the velocity equations only while an iterative approach such as Schur complement reduction used to solve the outer velocity-pressure equations. In the coupled approach, on the other hand, a multigrid approach is applied to both the velocity and pressure equations. The coupled multigrid approaches are typically employed in combination with staggered finite difference discretizations, whereas the decoupled approach is the method of choice in many of the existing finite element codes. Yet, it is unclear whether there are differences in speed between the two approaches, and if so, how this depends on the initial guess. Here, we implemented both approaches in combination with a staggered finite difference discretization and test the robustness of the two approaches with respect to large jumps in viscosity contrast, as well as their computational efficiency as a function of the initial guess. Acknowledgements. Funding was provided by the European Research Council under the European Community's Seventh Framework Program (FP7/2007-2013) / ERC Grant agreement #258830. Numerical computations have been performed on JUQUEEN of the Jülich high-performance computing center.

  15. Plastic Pollution in the World's Oceans: More than 5 Trillion Plastic Pieces Weighing over 250,000 Tons Afloat at Sea.

    PubMed

    Eriksen, Marcus; Lebreton, Laurent C M; Carson, Henry S; Thiel, Martin; Moore, Charles J; Borerro, Jose C; Galgani, Francois; Ryan, Peter G; Reisser, Julia

    2014-01-01

    Plastic pollution is ubiquitous throughout the marine environment, yet estimates of the global abundance and weight of floating plastics have lacked data, particularly from the Southern Hemisphere and remote regions. Here we report an estimate of the total number of plastic particles and their weight floating in the world's oceans from 24 expeditions (2007-2013) across all five sub-tropical gyres, costal Australia, Bay of Bengal and the Mediterranean Sea conducting surface net tows (N = 680) and visual survey transects of large plastic debris (N = 891). Using an oceanographic model of floating debris dispersal calibrated by our data, and correcting for wind-driven vertical mixing, we estimate a minimum of 5.25 trillion particles weighing 268,940 tons. When comparing between four size classes, two microplastic <4.75 mm and meso- and macroplastic >4.75 mm, a tremendous loss of microplastics is observed from the sea surface compared to expected rates of fragmentation, suggesting there are mechanisms at play that remove <4.75 mm plastic particles from the ocean surface.

  16. Localization and propagation of the energy release during 3D kinetic magnetic reconnection

    NASA Astrophysics Data System (ADS)

    Lapenta, Giovanni; Markidis, Stefano; Goldman, Marty; Newman, David

    2013-04-01

    Reconnection is a key processes where energy is released: magnetic field lines break, merge in a new configuration. In the process some of the energy is released. Recent work by Shay and collaborators has pointed out that energy is released far and moving fast away from the reconnection site, at a speed exceeding several times the Alfven speed. We revisit this point, considering the release of energy from reconnection and considering both laminar processes and turbulent reconnection. We analyse the energy budget and the processes of energy transfer via Poynting flux and particle flows. The results are compared with the recent findings by Shay. The effect of the guide field can be very significant at even relatively weak strength, as our recent analysis shows. The effect on the life cycle of energy is considered. The research leading to these results has received funding from the European Commission's Seventh Framework Programme (FP7/2007-2013) under the grant agreement SWIFF (project n° 263340, www.swiff.eu). [1] M. A. Shay, J. F. Drake, J. P. Eastwood, and T. D. Phan, Super-Alfvénic Propagation of Substorm Reconnection Signatures and Poynting Flux, Phys. Rev. Lett. 107, 089901, 2011. [2] M.V. Goldman, G. Lapenta, D. L. Newman, S. Markidis, H. Che, Jet Deflection by Very Weak Guide Fields during Magnetic Reconnection, Physical Review Letters, 107, 135001, 2011.

  17. Longitudinal Transient Elastography Measurements Used in Follow-up for Patients with Cystic Fibrosis.

    PubMed

    Van Biervliet, Stephanie; Verdievel, Hugo; Vande Velde, Saskia; De Bruyne, Ruth; De Looze, Danny; Verhelst, Xavier; Geerts, Anja; Robberecht, Eddy; Van Vlierberghe, Hans

    2016-04-01

    Cystic fibrosis-related liver disease (CFLD) is diagnosed using a combination of criteria. Transient elastography (TE), an ultrasonographic method to evaluate liver stiffness, can differentiate patients with and without liver disease. This retrospective study (2007-2013) aimed to detect developing CFLD using consequent TE measurements. All cystic fibrosis patients with TE measurements between 2007 and 2013 (n = 150, median age 17 (9-24) y) were included, of which 118 had a median of three (range, 2-4) measurements with an interval of 1 (1-2) y. Twenty (14%) had CFLD at the first TE measurement; five (3%) developed CFLD during follow-up. The median TE value in CFLD was 14 kPa (8.7-32.2) compared with 5.3 (4.9-5.7) in cystic fibrosis patients without liver disease (CFnoLD; p = 0.0001). In CFnoLD, TE was correlated with age (p = 0.031). A TE result >6.8 kPa had a sensitivity of 91.5% and a specificity of 91.7% in predicting CFLD, according to the receiver operating characteristics analysis. It also has a positive predictive value of 88.6% and a negative predictive value of 86.9%, increasing to 91.7% and 98%, respectively, in patients at risk (<14 y) for developing CFLD. Patients with developing CFLD had progressively increasing consecutive TE measurements.

  18. Wall-layer model for LES with massive separation

    NASA Astrophysics Data System (ADS)

    Fakhari, Ahmad; Armenio, Vincenzo; Roman, Federico

    2016-11-01

    Currently, Wall Functions (WF) work well under specific conditions, mostly exhibit drawbacks specially in flows with separation beyond curvatures. In this work, we propose a more general WF which works well in attached and detached flows, in presence and absence of Immersed Boundaries (IB). First we modified an equilibrium stress WF for boundary-fitted geometry making dynamic the computation of the k (von Karman constant) of the log-law; the model was first applied to a periodic open channel flow, and then to the flow over a 2D single hill using uniform coarse grids; the model captured separation with reasonable accuracy. Thereafter IB Method by Roman et al. was improved to avoid momentum loss at the interface between the fluid-solid regions. This required calibration of interfacial eddy viscosity; also a random stochastic forcing was used in wall-normal direction to increase Reynolds stresses and improve mean velocity profile. Finally, to reproduce flow separation, a simplified boundary layer equation was applied to construct velocity at near wall computational nodes. The new scheme was tested on the 2D single hill and periodic hills applying Cartesian and curvilinear grids; good agreement with references was obtained with reduction in cost and complexity. Financial support from project COSMO "CFD open source per opera morta" PAR FSC 2007-2013, Friuli Venezia Giulia.

  19. Massive separation around bluff bodies: comparisons among different cfd solvers and turbulence models

    NASA Astrophysics Data System (ADS)

    Armenio, Vincenzo; Fakhari, Ahmad; Petronio, Andrea; Padovan, Roberta; Pittaluga, Chiara; Caprino, Giovanni

    2015-11-01

    Massive flow separation is ubiquitous in industrial applications, ruling drag and hydrodynamic noise. In spite of considerable efforts, its numerical prediction still represents a challenge for CFD models in use in engineering. Aside commercial software, over the latter years the opensource software OpenFOAMR (OF) has emerged as a valid tool for prediction of complex industrial flows. In the present work, we simulate two flows representative of a class of situations occurring in industrial problems: the flow around sphere and that around a wall-mounted square cylinder at Re = 10000 . We compare the performance two different tools, namely OF and ANSYS CFX 15.0 (CFX) using different unstructured grids and turbulence models. The grids have been generated using SNAPPYHEXMESH and ANSYS ICEM CFD 15.0 with different near wall resolutions. The codes have been run in a RANS mode using k - ɛ model (OF) and SST - k - ω (CFX) with and without wall-layer models. OF has been also used in LES, WMLES and DES mode. Regarding the sphere, RANS models were not able to catch separation, while good prediction of separation and distribution of stresses over the surface were obtained using LES, WMLES and DES. Results for the second test case are currently under analysis. Financial support from COSMO ``cfd open source per opera mortta'' PAR FSC 2007-2013, Friuli Venezia Giulia.

  20. Polymeric surfaces exhibiting photocatalytic activity and controlled anisotropic wettability

    NASA Astrophysics Data System (ADS)

    Anastasiadis, Spiros H.; Frysali, Melani A.; Papoutsakis, Lampros; Kenanakis, George; Stratakis, Emmanuel; Vamvakaki, Maria; Mountrichas, Grigoris; Pispas, Stergios

    2015-03-01

    In this work we focus on surfaces, which exhibit controlled, switchable wettability in response to one or more external stimuli as well as photocatalytic activity. For this we are inspired from nature to produce surfaces with a dual-scale hierarchical roughness and combine them with the appropriate inorganic and/or polymer coating. The combination of the hierarchical surface with a ZnO coating and a pH- or temperature-responsive polymer results in efficient photo-active properties as well as reversible superhydrophobic / superhydrophilic surfaces. Furthermore, we fabricate surfaces with unidirectional wettability variation. Overall, such complex surfaces require advanced design, combining hierarchically structured surfaces with suitable polymeric materials. Acknowledgment: This research was partially supported by the European Union (European Social Fund, ESF) and Greek national funds through the ``ARISTEIA II'' Action (SMART-SURF) of the Operational Programme ``Education and Lifelong Learning,'' NSRF 2007-2013, via the General Secretariat for Research & Technology, Ministry of Education and Religious Affairs, Greece.

  1. Gravity Waves in the Polar Stratosphere and Mesosphere and Their Relations with Ice Cloud Observed Sofie/AIM

    NASA Astrophysics Data System (ADS)

    Liu, X.; Yue, J.; Xu, J.; Wang, L.; Yuan, W.; Russell, J. M., III; Hervig, M. E.

    2014-12-01

    A six-years (2007-2013) temperature dataset from the Solar Occultation for Ice Experiment (SOFIE) onboard the Aeronomy of Ice in the Mesosphere (AIM) satellite is used to extract gravity waves (GWs) in the polar stratosphere and mesosphere of both hemispheres. These data are continuous in the polar regions. The monthly mean GW potential energy (PE) increases exponentially with a scale height of ~13 km in the upper stratosphere and mesosphere. GWs are stronger in the winter than in the summer and exhibit strong annual variation. GWs are stronger in the southern polar region (SPR) than in the northern polar region (NPR) except in the summer months. This is likely because there are stronger and longer-lasting zonal wind jets in the SPR stratosphere, as revealed from Modern-Era Retrospective analysis for Research and Applications (MERRA) wind data. The longitudinal variations of PE in the winter polar stratosphere are consistent with the elevated regions. In the mesosphere, the longitudinal variations of PE do not vary with height significantly. The correlations between GW PE and the column ice water content (IWC, an indicator of the polar mesosphere cloud) exhibit longitudinal and annual variations.

  2. Detecting plastic events in emulsions simulations

    NASA Astrophysics Data System (ADS)

    Lulli, Matteo; Matteo Lulli, Massimo Bernaschi, Mauro Sbragaglia Team

    2016-11-01

    Emulsions are complex systems which are formed by a number of non-coalescing droplets dispersed in a solvent leading to non-trivial effects in the overall flowing dynamics. Such systems possess a yield stress below which an elastic response to an external forcing occurs, while above the yield stress the system flows as a non-Newtonian fluid, i.e. the stress is not proportional to the shear. In the solid-like regime the network of the droplets interfaces stores the energy coming from the work exerted by an external forcing, which can be used to move the droplets in a non-reversible way, i.e. causing plastic events. The Kinetic-Elasto-Plastic (KEP) theory is an effective theory describing some features of the flowing regime relating the rate of plastic events to a scalar field called fluidity f =γ˙/σ , i.e. the inverse of an effective viscosity. Boundary conditions have a non-trivial role not captured by the KEP description. In this contribution we will compare numerical results against experiments concerning the Poiseuille flow of emulsions in microchannels with complex boundary geometries. Using an efficient computational tool we can show non-trivial results on plastic events for different realizations of the rough boundaries. The research leading to these results has received funding from the European Research Council under the European Community's Seventh Framework Programme (FP7/2007- 2013)/ERC Grant Agreement no. [279004].

  3. Assessing and optimizing infrasound network performance: application to remote volcano monitoring

    NASA Astrophysics Data System (ADS)

    Tailpied, D.; LE Pichon, A.; Marchetti, E.; Kallel, M.; Ceranna, L.

    2014-12-01

    Infrasound is an efficient monitoring technique to remotely detect and characterize explosive sources such as volcanoes. Simulation methods incorporating realistic source and propagation effects have been developed to quantify the detection capability of any network. These methods can also be used to optimize the network configuration (number of stations, geographical location) in order to reduce the detection thresholds taking into account seasonal effects in infrasound propagation. Recent studies have shown that remote infrasound observations can provide useful information about the eruption chronology and the released acoustic energy. Comparisons with near-field recordings allow evaluating the potential of these observations to better constrain source parameters when other monitoring techniques (satellite, seismic, gas) are not available or cannot be made. Because of its regular activity, the well-instrumented Mount Etna is in Europe a unique natural repetitive source to test and optimize detection and simulation methods. The closest infrasound station part of the International Monitoring System is located in Tunisia (IS48). In summer, during the downwind season, it allows an unambiguous identification of signals associated with Etna eruptions. Under the European ARISE project (Atmospheric dynamics InfraStructure in Europe, FP7/2007-2013), experimental arrays have been installed in order to characterize infrasound propagation in different ranges of distance and direction. In addition, a small-aperture array, set up on the flank by the University of Firenze, has been operating since 2007. Such an experimental setting offers an opportunity to address the societal benefits that can be achieved through routine infrasound monitoring.

  4. Analyzing injury severity factors at highway railway grade crossing accidents involving vulnerable road users: A comparative study.

    PubMed

    Ghomi, Haniyeh; Bagheri, Morteza; Fu, Liping; Miranda-Moreno, Luis F

    2016-11-16

    The main objective of this study is to identify the main factors associated with injury severity of vulnerable road users (VRUs) involved in accidents at highway railroad grade crossings (HRGCs) using data mining techniques. This article applies an ordered probit model, association rules, and classification and regression tree (CART) algorithms to the U.S. Federal Railroad Administration's (FRA) HRGC accident database for the period 2007-2013 to identify VRU injury severity factors at HRGCs. The results show that train speed is a key factor influencing injury severity. Further analysis illustrated that the presence of illumination does not reduce the severity of accidents for high-speed trains. In addition, there is a greater propensity toward fatal accidents for elderly road users compared to younger individuals. Interestingly, at night, injury accidents involving female road users are more severe compared to those involving males. The ordered probit model was the primary technique, and CART and association rules act as the supporter and identifier of interactions between variables. All 3 algorithms' results consistently show that the most influential accident factors are train speed, VRU age, and gender. The findings of this research could be applied for identifying high-risk hotspots and developing cost-effective countermeasures targeting VRUs at HRGCs.

  5. Detection of block movements in ortho-rectified HiRISE images of the north pole of Mars

    NASA Astrophysics Data System (ADS)

    Fanara, Lida; Gwinner, Klaus; Hauber, Ernst; Oberst, Juergen

    2016-04-01

    We are working toward automatically identifying new and disintegrated blocks at the foot of the steep north polar scarps of Mars. This region has been closely monitored by High Resolution Imaging Science Experiment (HiRISE) over the past 9 years. Repeated imaging revealed that mass movement events are very common at the steep margins of the polar cap. The most frequently observed events are block movements, which originate at the North Polar Layered Deposits (NPLD) or at the Basal Unit (BU). Blocks come to rest intact or after breaking up into smaller fragments. Their original sizes are in the order of a couple of cubic meters. We have manually identified hundreds of single-block movements as well as events involving a large number of blocks and are currently developing a process for detecting these automatically. First we accurately locate the events by ortho-rectifying the images using HiRISE Digital Terrain Models (DTMs). Then we use the resulting co-registered images taken at different times as the basis for change detection, at which stage we focus on retrieving the size and shape of the moved blocks in order to classify them according to specific geometric criteria. These results can be combined with the corresponding DTMs to estimate the volume of the mass movements. The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under iMars grant agreement n° 607379.

  6. Prevalence of human respiratory syncytial virus circulating in Iran.

    PubMed

    Salimi, Vahid; Tavakoli-Yaraki, Masoumeh; Yavarian, Jila; Bont, Louis; Mokhtari-Azad, Talat

    2016-01-01

    Respiratory syncytial virus (RSV) is a leading cause of acute respiratory infection during early childhood and is associated with a great burden on patients, parents, and society. While no treatment is yet available, results from recent phase 2 clinical trials of cell-entry inhibitors and RSV vaccines are promising. To prepare for introduction of these novel therapeutics, good understanding of its molecular epidemiology and continuous RSV surveillance data are necessary. This paper provides an overview of RSV prevalence and genotype distribution in Iran from 1996 to 2013. This meta-analysis includes 21 published studies. In total, 775 (18.7%) of 4140 respiratory specimens were positive for RSV infection. The male-female ratio of RSV-positive patients was 1.5:1. Significant peaks of RSV infection were detected during the cold season (November-March). RSV infection was mainly observed in patients <2 years of age. Phylogenetic studies showed that genotypes GA1, GA2, GA5, and BA co-circulated in Iran in 2007-2013. This review highlights the necessity of introducing standard molecular surveillance programs to inform the epidemiological, clinical, and pathological characteristics of various RSV genotypes. Improved understanding of the molecular epidemiology will be useful for development of novel RSV therapeutics.

  7. Landslide monitoring with combined methodology: geoelectrical anisotropy, PSInSAR and high precision leveling in Dunaszekcso, Hungary

    NASA Astrophysics Data System (ADS)

    Fusi, B.; Madarasi, A.

    2012-12-01

    The surface deformations in Hungary regarded as a priority source of geological hazards. The identification of the vulnerable parts of the affected areas, the impoundment and registration of the endangered territory and understanding of the mechanisms and triggering conditions are public tasks. In this case study we would like to present our two years achievements in the DORIS project (under grant agreement n° [242212]) within the European Union Seventh Framework Programme (FP7/2007-2013) in Dunaszekcso test area. After the regulation of the Danube, there are only few areas where high loess river banks can be found near the river bed, but there the ground deformation is continuous in this regions. The most affected area is Dunaszekcso, where several landslide events happened in the past, the last one in 2010 February. A new crack started to open in 2011 April. We monitored both the development of the crack with geoelectrical anisotropy measurements and the motion of the whole area with PSInSAR analysis (ALTAMIRA) and high precision leveling (GGKI). Since the area is densely populated, the main goal of these measurements is to predict the propagation of the subsurface crack in the loess river bank to provide information about the endangered areas before the next collapse. In my presentation I would like to introduce the test area, the applied methods and the achieved results.

  8. Temporal self-regulation theory: a neurobiologically informed model for physical activity behavior

    PubMed Central

    Hall, Peter A.; Fong, Geoffrey T.

    2015-01-01

    Dominant explanatory models for physical activity behavior are limited by the exclusion of several important components, including temporal dynamics, ecological forces, and neurobiological factors. The latter may be a critical omission, given the relevance of several aspects of cognitive function for the self-regulatory processes that are likely required for consistent implementation of physical activity behavior in everyday life. This narrative review introduces temporal self-regulation theory (TST; Hall and Fong, 2007, 2013) as a new explanatory model for physical activity behavior. Important features of the model include consideration of the default status of the physical activity behavior, as well as the disproportionate influence of temporally proximal behavioral contingencies. Most importantly, the TST model proposes positive feedback loops linking executive function (EF) and the performance of physical activity behavior. Specifically, those with relatively stronger executive control (and optimized brain structures supporting it, such as the dorsolateral prefrontal cortex (PFC)) are able to implement physical activity with more consistency than others, which in turn serves to strengthen the executive control network itself. The TST model has the potential to explain everyday variants of incidental physical activity, sport-related excellence via capacity for deliberate practice, and variability in the propensity to schedule and implement exercise routines. PMID:25859196

  9. Minimally adequate mental health care and latent classes of PTSD symptoms in female Iraq and Afghanistan veterans.

    PubMed

    Hebenstreit, Claire L; Madden, Erin; Koo, Kelly H; Maguen, Shira

    2015-11-30

    Female veterans of Operations Enduring and Iraqi Freedom, and Operation New Dawn (OEF/OIF/OND) represent a growing segment of Department of Veterans Affairs (VA) health care users. A retrospective analysis used national VA medical records to identify factors associated with female OEF/OIF/OND veterans' completion of minimally adequate care (MAC) for PTSD, defined as the completion of at least nine mental health outpatient visits within a 15-week period or at least twelve consecutive weeks of medication use. The sample included female OEF/OIF/OND veterans with PTSD who initiated VA health care between 2007-2013, and were seen in outpatient mental health (N=2183). Multivariable logistic regression models examined factors associated with completing MAC for PTSD, including PTSD symptom expression (represented by latent class analysis), sociodemographic, military, clinical, and VA access factors. Within one year of initiating mental health care, 48.3% of female veterans completed MAC. Race/ethnicity, age, PTSD symptom class, additional psychiatric diagnoses, and VA primary care use were significantly associated with completion of MAC for PTSD. Results suggest that veterans presenting for PTSD treatment should be comprehensively evaluated to identify factors associated with inadequate completion of care. Treatments that are tailored to PTSD symptom class may help to address potential barriers. Published by Elsevier Ireland Ltd.

  10. Comparison of Health Examination Survey Methods in Brazil, Chile, Colombia, Mexico, England, Scotland, and the United States.

    PubMed

    Mindell, Jennifer S; Moody, Alison; Vecino-Ortiz, Andres I; Alfaro, Tania; Frenz, Patricia; Scholes, Shaun; Gonzalez, Silvia A; Margozzini, Paula; de Oliveira, Cesar; Sanchez Romero, Luz Maria; Alvarado, Andres; Cabrera, Sebastián; Sarmiento, Olga L; Triana, Camilo A; Barquera, Simón

    2017-09-15

    Comparability of population surveys across countries is key to appraising trends in population health. Achieving this requires deep understanding of the methods used in these surveys to examine the extent to which the measurements are comparable. In this study, we obtained detailed protocols of 8 nationally representative surveys from 2007-2013 from Brazil, Chile, Colombia, Mexico, the United Kingdom (England and Scotland), and the United States-countries that that differ in economic and inequity indicators. Data were collected on sampling frame, sample selection procedures, recruitment, data collection methods, content of interview and examination modules, and measurement protocols. We also assessed their adherence to the World Health Organization's "STEPwise Approach to Surveillance" framework for population health surveys. The surveys, which included half a million participants, were highly comparable on sampling methodology, survey questions, and anthropometric measurements. Heterogeneity was found for physical activity questionnaires and biological samples collection. The common age range included by the surveys was adults aged 18-64 years. The methods used in these surveys were similar enough to enable comparative analyses of the data across the 7 countries. This comparability is crucial in assessing and comparing national and subgroup population health, and to assisting the transfer of research and policy knowledge across countries. © The Author(s) 2017. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  11. Changes in mood stabilizer prescription patterns in bipolar disorder.

    PubMed

    Karanti, Alina; Kardell, Mathias; Lundberg, Ulrika; Landén, Mikael

    2016-05-01

    Lithium is a first line treatment option in bipolar disorder, but several alternative treatments have been introduced in recent years, such as antiepileptic and atypical antipsychotic drugs. Little is known about how this has changed the prescription patterns. We investigated possible changes in the use of mood stabilizers and antidepressants in Sweden during 2007-2013. Data was collected from Swedish registers: the National Quality Assurance Register for bipolar disorder (BipoläR), the Prescribed Drug Register, and the Patient Register. Logistic regression models with drug use as outcomes were used to adjust for confounding factors such as sex, age, year of registration, and subtypes of bipolar disorder. In both bipolar subtypes, lithium use decreased steadily during the study period, while the use of lamotrigine and quetiapine increased. The use of valproate decreased in bipolar II disorder and the use of olanzapine decreased among women. The use of antidepressant remained principally unchanged but increased somewhat in bipolar I disorder. We only report data from 2007 as the coverage of BipoläR prior to 2007 was too low to allow for reliable analyses. Significant changes in the prescription of drugs in the treatment of bipolar disorder have occurred in recent years in Sweden. Further studies are needed to clarify whether these changes alter the outcome in bipolar disorder. Copyright © 2016 Elsevier B.V. All rights reserved.

  12. Improved retrieval of total and tropospheric NO2 column for GOME-2

    NASA Astrophysics Data System (ADS)

    Liu, Song; Valks, Pieter; Pinardi, Gaia; De Smedt, Isabelle; Yu, Huan; Beirle, Steffen

    2017-04-01

    This contribution focuses on the algorithm refinement for the retrieval of total and tropospheric nitrogen dioxide (NO2) columns for the GOME-2 satellite instrument. The improved algorithm will be implemented in the upcoming version of the operational GOME Data Processor (GDP) at the German Aerospace Center (DLR). A larger 425-497 nm wavelength fitting window is used in the differential optical absorption spectroscopy (DOAS) retrieval of the NO2 slant column density. The reference spectra are updated, and the GOME-2 slit function variations over time and along orbit is taken into account. In addition, the effect of the new level 1b data version 6.1 on the retrieved NO2 slant column is analyzed. The STRatospheric Estimation Algorithm from Mainz (STREAM) is applied to determine the stratospheric column density of NO2. For the calculation of the tropospheric AMF, a new surface albedo climatology based on GOME-2 observations for 2007-2013 and a priori NO2 profile obtained from the chemical transport model IMAGESv2 are used. We present the improvements in the NO2 retrieval algorithm and show comparisons with OMI NO2 data. Furthermore, we show examples of air quality applications with GOME-2 NO2 data.

  13. Professional training in nutrition in Central and Eastern Europe: current status and opportunities for capacity development.

    PubMed

    Gurinović, Mirjana; Novaković, Romana; Šatalić, Zvonimir; Nikolić, Marina; Milešević, Jelena; Ranić, Marija; Glibetić, Marija

    2015-02-01

    To examine the availability of academic programmes in nutrition and identify nutrition training needs in Central and Eastern Europe (CEE). A questionnaire with close-ended and open-ended questions was distributed to the members of the United Nations University Standing Committee on Nutrition, Regional Network for Capacity Development in Nutrition in CEE (NCDN CEE). Participants' responses to the questionnaire including the comments of their colleagues from home institutions were obtained in group discussions during NCDN CEE meetings in 2010-2013. Sixteen CEE countries' experts and their colleagues from home institutions involved in NCDN CEE activities 2007-2013. The responses were obtained from fourteen out of sixteen participating countries; five countries have established Bachelor, Master and PhD studies in nutrition (Croatia, Czech Republic, Poland, Slovak Republic and Slovenia), whereas in Latvia and Republic of Macedonia only Bachelor and Master studies are set up. Seven countries have no Bachelor, Master or PhD studies: Bosnia and Herzegovina, Bulgaria, Estonia, Lithuania, Montenegro, Romania and Serbia. Introduction to data analysis and Nutritional epidemiology are the most needed nutrition trainings that would increase working competence of nutritionists and nutrition-related professionals in CEE. Availability of academic programmes in nutrition in CEE countries is limited. Opportunities for improving the competence of existing and future nutrition-related professionals should be addressed at national and regional level; distance learning courses and creation of a regional centre for nutrition training were seen as opportunities for sustainable capacity development in nutrition in CEE.

  14. Acute Gastrointestinal Illness Risks in North Carolina Community Water Systems: A Methodological Comparison.

    PubMed

    DeFelice, Nicholas B; Johnston, Jill E; Gibson, Jacqueline MacDonald

    2015-08-18

    The magnitude and spatial variability of acute gastrointestinal illness (AGI) cases attributable to microbial contamination of U.S. community drinking water systems are not well characterized. We compared three approaches (drinking water attributable risk, quantitative microbial risk assessment, and population intervention model) to estimate the annual number of emergency department visits for AGI attributable to microorganisms in North Carolina community water systems. All three methods used 2007-2013 water monitoring and emergency department data obtained from state agencies. The drinking water attributable risk method, which was the basis for previous U.S. Environmental Protection Agency national risk assessments, estimated that 7.9% of annual emergency department visits for AGI are attributable to microbial contamination of community water systems. However, the other methods' estimates were more than 2 orders of magnitude lower, each attributing 0.047% of annual emergency department visits for AGI to community water system contamination. The differences in results between the drinking water attributable risk method, which has been the main basis for previous national risk estimates, and the other two approaches highlight the need to improve methods for estimating endemic waterborne disease risks, in order to prioritize investments to improve community drinking water systems.

  15. The influence of year, laying date, egg fertility and incubation, individual hen, hen age and mass and clutch size on maternal immunoglobulin Y concentration in captive Steller's and spectacled eider egg yolk.

    PubMed

    Counihan, Katrina L; Maniscalco, John M; Bozza, Maryann; Hendon, Jill M; Hollmén, Tuula E

    2015-09-01

    Steller's eiders and spectacled eiders are sea duck species whose populations have declined significantly and infectious diseases could influence offspring survival. Therefore, the maternal transfer of immunoglobulin Y (IgY) into yolk was investigated in captive Steller's and spectacled eiders during the 2007-2013 breeding seasons. This project had two objectives: establish baseline IgY levels in Steller's and spectacled eider yolk under controlled captive conditions and evaluate the effect of year, laying date, egg fertility, egg incubation duration, individual hen, hen age and mass, and laying order to determine which variables influenced IgY levels. Average IgY concentrations were 0.03-0.48 mg ml(-1) in Steller's eider yolk and 0.10-0.51 mg ml(-1) in spectacled eider yolk. The year and individual hen influenced IgY concentration in Steller's and spectacled eider yolk. The laying date was negatively correlated with egg IgY levels for most Steller's eider hens, but laying order was positively correlated with egg IgY concentration for spectacled eiders.

  16. Examining the Starting Dose of Glyburide in Gestational Diabetes

    PubMed Central

    GLOVER, Angelica V.; TITA, Alan; BIGGIO, Joseph R.; HARPER, Lorie M.

    2016-01-01

    OBJECTIVE The aim of this study was to determine the impact of initial glyburide dosing on pregnancy outcomes. STUDY DESIGN Retrospective cohort of singleton pregnancies complicated by gestational diabetes (GDM) from 2007-2013. Women who received glyburide were compared by initial dose: 2.5mg (n=170) versus 5mg (n=154) total daily dose. The primary maternal outcome was hypoglycemia, defined as a blood glucose <60 mg/dL. The primary neonatal outcome was birth weight. Secondary maternal outcomes included time to blood glucose control, preeclampsia, and cesarean delivery. Secondary neonatal outcomes included macrosomia (>4000g), hypoglycemia (<40 mg/dL), shoulder dystocia, and preterm delivery. RESULTS The 5 mg/day glyburide dose did not increase maternal hypoglycemia (26% in the 2.5 mg/day group versus 27% in the 5 mg/day group, AOR 0.67 (CI 0.30-1.49)). An increase in macrosomia in the 5 mg/day group was not significant after adjusting for maternal obesity (AOR 2.16 (CI 0.96-4.88)). Differences in preterm birth and large for gestational age were not significant after adjusting for prior preterm birth and maternal obesity, respectively. CONCLUSIONS A higher starting dose of glyburide for the management of GDM was not associated with increased maternal hypoglycemia or decreased adverse neonatal outcomes. PMID:26368915

  17. Tobacco control campaign in Uruguay: Impact on smoking cessation during pregnancy and birth weight.

    PubMed

    Harris, Jeffrey E; Balsa, Ana Inés; Triunfo, Patricia

    2015-07-01

    We analyzed a nationwide registry of all pregnancies in Uruguay during 2007-2013 to assess the impact of three types of tobacco control policies: (1) provider-level interventions aimed at the treatment of nicotine dependence, (2) national-level increases in cigarette taxes, and (3) national-level non-price regulation of cigarette packaging and marketing. We estimated models of smoking cessation during pregnancy at the individual, provider and national levels. The rate of smoking cessation during pregnancy increased from 15.4% in 2007 to 42.7% in 2013. National-level non-price policies had the largest estimated impact on cessation. The price response of the tobacco industry attenuated the effects of tax increases. While provider-level interventions had a significant effect, they were adopted by relatively few health centers. Quitting during pregnancy increased birth weight by an estimated 188 g. Tobacco control measures had no effect on the birth weight of newborns of non-smoking women.

  18. Water pipes and E-cigarettes: new faces of an ancient enemy.

    PubMed

    Dagaonkar, Rucha S; Udwadi, Zarir F

    2014-04-01

    In a world grappling with tobacco addiction, the hookah (water-pipe) and the electronic cigarette (e-cigarette) are creating new problems. Apart from posing the inherent danger of nicotine addiction, they both seem to be wolves cloaked in the sheep-skin of consumer-perceived safety, at least in comparison to the cigarette. However it seems that the e-cigarette may have a role in a nicotine-replacement therapy. There has been a wave of interest around the world in analysing these phenomena. The following review discusses the current data regarding the hookah and the e-cigarette. A PubMed, Medline and Google search using the keywords'sheesha', 'hookah', water-pipe', 'electronic cigarette', 'e-cigarette', 'vapers' was carried out.The studies carried out between 2007-2013 were included in this review. Information available in the public domain on internet websites was included to study the perception of the lay consumer regarding the hookah and the e-cigarette.

  19. Wolverine behavior varies spatially with anthropogenic footprint: implications for conservation and inferences about declines.

    PubMed

    Stewart, Frances E C; Heim, Nicole A; Clevenger, Anthony P; Paczkowski, John; Volpe, John P; Fisher, Jason T

    2016-03-01

    Understanding a species' behavioral response to rapid environmental change is an ongoing challenge in modern conservation. Anthropogenic landscape modification, or "human footprint," is well documented as a central cause of large mammal decline and range contractions where the proximal mechanisms of decline are often contentious. Direct mortality is an obvious cause; alternatively, human-modified landscapes perceived as unsuitable by some species may contribute to shifts in space use through preferential habitat selection. A useful approach to tease these effects apart is to determine whether behaviors potentially associated with risk vary with human footprint. We hypothesized wolverine (Gulo gulo) behaviors vary with different degrees of human footprint. We quantified metrics of behavior, which we assumed to indicate risk perception, from photographic images from a large existing camera-trapping dataset collected to understand wolverine distribution in the Rocky Mountains of Alberta, Canada. We systematically deployed 164 camera sites across three study areas covering approximately 24,000 km(2), sampled monthly between December and April (2007-2013). Wolverine behavior varied markedly across the study areas. Variation in behavior decreased with increasing human footprint. Increasing human footprint may constrain potential variation in behavior, through either restricting behavioral plasticity or individual variation in areas of high human impact. We hypothesize that behavioral constraints may indicate an increase in perceived risk in human-modified landscapes. Although survival is obviously a key contributor to species population decline and range loss, behavior may also make a significant contribution.

  20. HIFU therapy for local recurrence of prostate cancer after external beam radiotherapy and radical prostatectomy - 5,5 years experience

    NASA Astrophysics Data System (ADS)

    Solovov, V. A.; Vozdvizhenskiy, M. O.; Matysh, Y. S.

    2017-03-01

    Objectives. To evaluate the clinical efficacy of high-intensity focused ultrasound ablation (HIFU) for local recurrence of prostate cancer after external beam radiotherapy (EBRT) and radical prostatectomy (RPE). Materials and Methods: During 2007-2013 years 47 patients with local recurrence of prostate cancer after EBRT and RPE undertook HIFU therapy on the system "Ablaterm» (EDAP, France). Relapse arose after an average of 2 years after EBRT and RPE. Median follow-up after HIFU therapy was 38 (12-60) months. The mean age was 68.5 ± 5.8 years. The median PSA level before HIFU - 15.4 (7-48) ng / mL. Results: In 34 patients (72.3%) at six months after treatment the median PSA was 0.4 (0-3.2) ng / mL, in 48 months - 0.9 (0.4-7.5) ng / mL. In 13 patients (27.7%) at 6 months was observed progression of the disease. In general, after a 5-year follow-up 72.3% of the patients had no data for the progression and recurrence. Conclusion: HIFU therapy in patients with local recurrence of prostate cancer after EBRT and RPE is minimally invasive and effective technology.

  1. In-depth discrimination of aerosol types using multiple clustering techniques over four locations in Indo-Gangetic plains

    NASA Astrophysics Data System (ADS)

    Bibi, Humera; Alam, Khan; Bibi, Samina

    2016-11-01

    Discrimination of aerosol types is essential over the Indo-Gangetic plain (IGP) because several aerosol types originate from different sources having different atmospheric impacts. In this paper, we analyzed a seasonal discrimination of aerosol types by multiple clustering techniques using AERosol RObotic NETwork (AERONET) datasets for the period 2007-2013 over Karachi, Lahore, Jaipur and Kanpur. We discriminated the aerosols into three major types; dust, biomass burning and urban/industrial. The discrimination was carried out by analyzing different aerosol optical properties such as Aerosol Optical Depth (AOD), Angstrom Exponent (AE), Extinction Angstrom Exponent (EAE), Abortion Angstrom Exponent (AAE), Single Scattering Albedo (SSA) and Real Refractive Index (RRI) and their interrelationship to investigate the dominant aerosol types and to examine the variation in their seasonal distribution. The results revealed that during summer and pre-monsoon, dust aerosols were dominant while during winter and post-monsoon prevailing aerosols were biomass burning and urban industrial, and the mixed type of aerosols were present in all seasons. These types of aerosol discriminated from AERONET were in good agreement with CALIPSO (the Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observation) measurement.

  2. The contribution of genomic research to explaining racial disparities in cardiovascular disease: a systematic review.

    PubMed

    Kaufman, Jay S; Dolman, Lena; Rushani, Dinela; Cooper, Richard S

    2015-04-01

    After nearly a decade of genome-wide association studies, no assessment has yet been made of their contribution toward an explanation of the most prominent racial health disparities observed at the population level. We examined populations of African and European ancestry and focused on cardiovascular diseases, which are collectively the largest contributor to the racial mortality gap. We conducted a systematic search for review articles and meta-analyses published in 2007-2013 in which genetic data from both populations were available. We identified 68 articles relevant to this question; however, few reported significant associations in both racial groups, with just 3 variants meeting study-specific significance criteria. For most outcomes, there were too few estimates for quantitative summarization, but when summarization was possible, racial group did not contribute to heterogeneity. Most associations reported from genome-wide searches were small, difficult to replicate, and in no consistent direction that favored one racial group or another. Although the substantial investment in this technology might have produced clinical advances, it has thus far made little or no contribution to our understanding of population-level racial health disparities in cardiovascular disease. © The Author 2015. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  3. Observational and Modeling-based Study of Electrified Thunderstorms in Corsica

    NASA Astrophysics Data System (ADS)

    Defer, Eric; Pinty, Jean-Pierre; Coquillat, Sylvain; Prieur, Serge; Lambert, Dominique; Pedeboy, Stéphane

    2017-04-01

    To demonstrate the strong synergy between instrumentation and modeling tools to support the interpretation of lightning optical data of up-coming space-based geostationary missions, the temporal and spatial evolution of two thunderstorms in Corsica, one with a regular polarity (25 July 2014) and one with an inverted polarity (13 June 2015), were investigated through a detailed analysis of concurrent observations and numerical simulations. The electrical activity was simultaneously documented with the Lightning Mapping Array SAETTA (Suivi de l'Activité Electrique Tridimensionnelle Totale de l'Atmosphère; this conference) operated in Corsica since July 2014 and with the French operational lightning detection network Météorage. The cloud resolving model MesoNH and its explicit electrification and lightning schemes, successively simulated the spatial and temporal locations of the storms but also the number of flashes and the storm polarity. Both SAETTA and Meteorage networks, and MesoNH electrification and lightning modules will be first introduced. Then, observations and simulations will be discussed for the two studied storms with an emphasis on the causes of the different storm polarities. Acknowledgments: ANR-16-CE04-005 EXAEDRE project; the MISTRALS/HyMeX Program; Collectivité Territoriale de Corse through the Fonds Européen de Développement Régional of the European Operational Program 2007-2013 and the Contrat de Plan Etat Région;

  4. Human papillomavirus and its clinical relevance in oesophageal squamous cell carcinoma in a Kurdish population in the west of Iran.

    PubMed

    Soheili, Fariborz; Heidary, Nilofar; Rahbar, Mahtab; Nikkho, Bahram; Fotouhi, Omid; Afkhamzadeh, Abdolrahim; Jafari, Hossein; Bagheri, Vahid

    2016-04-01

    Background The aetiological role of Human Papillomavirus (HPV) in oesophageal squamous cell carcinoma (ESCC) was evaluated by assessment of the presence and status of HPV DNA in a Kurdish population in the west of Iran. Methods One hundred and three paraffin-embedded ESCC tissue samples, diagnosed between 2007-2013, were included in the study. DNA was extracted and then HPV presence and genotypes were determined by PCR and INNO-LiPA genotyping, respectively. Results HPV DNA was detected in 11/103 (10.7%) of ESCCs. HPV-18 and HPV-16 genotypes were determined in five and six samples, respectively. Co-infection of HPV-6 was only found with HPV-18 in two cases. There were no statistically significant distinctions between HPV-positive and HPV-negative cases with regard to clinical and pathologic findings. Conclusion The present study indicates that, among a group of Kurdish people in two provinces in the west of Iran, as a low-risk ESCC area, HPV could be one of the risk factors, although in a small proportion of the patients.

  5. A NEW ACCRETION DISK AROUND THE MISSING LINK BINARY SYSTEM PSR J1023+0038

    SciTech Connect

    Patruno, A.; Archibald, A. M.; Hessels, J. W. T.; Bassa, C. G.; Janssen, G. H.; Bogdanov, S.; Stappers, B. W.; Lyne, A. G.; Kaspi, V. M.; Tendulkar, S.

    2014-01-20

    PSR J1023+0038 is an exceptional system for understanding how slowly rotating neutron stars are spun up to millisecond rotational periods through accretion from a companion star. Observed as a radio pulsar from 2007-2013, optical data showed that the system had an accretion disk in 2000/2001. Starting at the end of 2013 June, the radio pulsar has become undetectable, suggesting a return to the previous accretion-disk state, where the system more closely resembles an X-ray binary. In this Letter we report the first targeted X-ray observations ever performed of the active phase and complement them with UV/optical and radio observations collected in 2013 October. We find strong evidence that indeed an accretion disk has recently formed in the system and we report the detection of fast X-ray changes spanning about two orders of magnitude in luminosity. No radio pulsations are seen during low flux states in the X-ray light curve or at any other times.

  6. Measuring Transitions in Sexual Risk Among Men Who Have Sex With Men: The Novel Use of Latent Class and Latent Transition Analysis in HIV Sentinel Surveillance.

    PubMed

    Wilkinson, Anna L; El-Hayek, Carol; Fairley, Christopher K; Roth, Norm; Tee, B K; McBryde, Emma; Hellard, Margaret; Stoové, Mark

    2017-03-10

    New combination human acquired deficiency (HIV) prevention strategies that include biomedical and primary prevention approaches add complexity to the task of measuring sexual risk. Latent transition models are beneficial for understanding complex phenomena; therefore, we trialed the application of latent class and latent transition models to HIV surveillance data. Our aims were to identify sexual risk states and model individuals' transitions between states. A total of 4,685 HIV-negative men who have sex with men (MSM) completed behavioral questionnaires alongside tests for HIV and sexually transmissible infections at one of 2 Melbourne, Victoria, Australia, general practices (2007-2013). We found 4 distinct classes of sexual risk, which we labeled "monogamous" (n = 1,224), "risk minimizer" (n = 1,443), "risk potential" (n = 1,335), and "risk taker" (n = 683). A positive syphilis, gonorrhea, or chlamydia test was significantly associated with class membership. Among a subset of 516 MSM who had at least 3 clinic visits, there was general stability across risk classes; MSM had on average a 0.70 (i.e., 70%) probability of remaining in the same class between visits 1 and 2 and between visits 2 and 3. Monogamous MSM were one exception; the probability of remaining in the monogamous class was 0.51 between visits 1 and 2. Latent transition analyses identified unobserved risk patterns in surveillance data, characterized high-risk MSM, and quantified transitions over time.

  7. Intermittency of solar system plasma turbulence near Venus and Earth

    NASA Astrophysics Data System (ADS)

    Teodorescu, Eliza; Echim, Marius; Chang, Tom

    2016-04-01

    We analyze magnetic field data from Venus Express (VEX) and CLUSTER to investigate the turbulent properties of the solar wind and the Earth's and Venus' magnetosheaths. A systematic study of the PDFs (Probability Distribution Functions) of the measured magnetic fluctuations and their fourth order moments (kurtosis) reveals numerous intermittent time series. The presence of intermittency is marked by non-Gaussian PDFs with heavy wings and a scale dependent kurtosis. Higher order analyses on the scale dependence of several moment orders of the PDFs, the structure functions, along with the scaling of the kurtosis allow for a selection of scales that pertain to different scaling regimes, governed by different physics. On such sub-ranges of scales we investigate the fractal structure of fluctuations through the Rank Ordered Multifractal Analysis - ROMA (Chang and Wu, 2008). ROMA is applied to a selection of intermittent magnetic field time series in the solar wind and planetary magnetosheaths and helps to quantify the turbulence properties through the estimation of a spectrum of local Hurst exponents. Research supported by the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement no 313038/STORM, and a grant of the Romanian Ministry of National Education, CNCS - UEFISCDI, project number PN-II-ID-PCE-2012-4-0418.

  8. Temporal self-regulation theory: a neurobiologically informed model for physical activity behavior.

    PubMed

    Hall, Peter A; Fong, Geoffrey T

    2015-01-01

    Dominant explanatory models for physical activity behavior are limited by the exclusion of several important components, including temporal dynamics, ecological forces, and neurobiological factors. The latter may be a critical omission, given the relevance of several aspects of cognitive function for the self-regulatory processes that are likely required for consistent implementation of physical activity behavior in everyday life. This narrative review introduces temporal self-regulation theory (TST; Hall and Fong, 2007, 2013) as a new explanatory model for physical activity behavior. Important features of the model include consideration of the default status of the physical activity behavior, as well as the disproportionate influence of temporally proximal behavioral contingencies. Most importantly, the TST model proposes positive feedback loops linking executive function (EF) and the performance of physical activity behavior. Specifically, those with relatively stronger executive control (and optimized brain structures supporting it, such as the dorsolateral prefrontal cortex (PFC)) are able to implement physical activity with more consistency than others, which in turn serves to strengthen the executive control network itself. The TST model has the potential to explain everyday variants of incidental physical activity, sport-related excellence via capacity for deliberate practice, and variability in the propensity to schedule and implement exercise routines.

  9. Electrical-optical characterization of multijunction solar cells under 2000X concentration

    NASA Astrophysics Data System (ADS)

    Bonsignore, Gaetano; Gallitto, Aurelio Agliolo; Agnello, Simonpietro; Barbera, Marco; Candia, Roberto; Cannas, Marco; Collura, Alfonso; Dentici, Ignazio; Gelardi, Franco Mario; Cicero, Ugo Lo; Montagnino, Fabio Maria; Paredes, Filippo; Sciortino, Luisa

    2014-09-01

    In the framework of the FAE "Fotovoltaico ad Alta Efficienza" ("High Efficiency Photovoltaic") Research Project (PO FESR Sicilia 2007/2013 4.1.1.1), we have performed electrical and optical characterizations of commercial InGaP/InGaAs/Ge triple-junction solar cells (1 cm2) mounted on a prototype HCPV module, installed in Palermo (Italy). This system uses a reflective optics based on rectangular off-axis parabolic mirror with aperture 45×45 cm2 leading to a geometrical concentration ratio of 2025. In this study, we report the I-V curve measured under incident power of about 700 W/m2 resulting in an electrical power at maximum point (PMP) of 41.4 W. We also investigated the optical properties by the electroluminescence (EL) spectra of the top (InGaP) and middle (InGaAs) subcells. From the analysis of the experimental data we extracted the bandgap energies of these III-V semiconductors in the range 305÷385 K.

  10. Self-crumpling elastomers: bending motion induced by a drying stimulus

    NASA Astrophysics Data System (ADS)

    Boulogne, François; Stone, Howard A.

    2014-11-01

    Capillary forces exerted by a liquid drop can bend elastic slender structures such as fibers or sheets. However, to successfully achieve capillary origami with sheets, it is important to make sure that the adhesion of the elastomer with the surface is low. We report an experimental study of the drying-induced peeling of a bilayer consisting of an elastomeric disk coated with a suspension of nanoparticles. We show that where capillary forces associated with the scale of the droplet can not compete with the adhesion of the elastomer on a surface, nevertheless large tensile stress developed in the coating, which resulted in a moment bending the bilayer. We attribute this stress to the nano-menisci in the pores of the colloidal material and we propose a model that describes successfully the early stage curvature of the bilayer. Thus, we show that the peeling can be conveniently controlled by the particle size and the coating thickness. We believe that such systems can be employed in various situations where delicate surfaces are involved such as in applications with optical and electronic components or in restoration of photographies, painting, wallpaper, fragile collectibles from contamination by dust, pollen, dirt, etc. The research leading to these results received funding from the People Programme (Marie Curie Actions) of the European Union's Seventh Framework Programme (FP7/2007-2013) under REA Grant Agreement 623541.

  11. Financial time series analysis based on information categorization method

    NASA Astrophysics Data System (ADS)

    Tian, Qiang; Shang, Pengjian; Feng, Guochen

    2014-12-01

    The paper mainly applies the information categorization method to analyze the financial time series. The method is used to examine the similarity of different sequences by calculating the distances between them. We apply this method to quantify the similarity of different stock markets. And we report the results of similarity in US and Chinese stock markets in periods 1991-1998 (before the Asian currency crisis), 1999-2006 (after the Asian currency crisis and before the global financial crisis), and 2007-2013 (during and after global financial crisis) by using this method. The results show the difference of similarity between different stock markets in different time periods and the similarity of the two stock markets become larger after these two crises. Also we acquire the results of similarity of 10 stock indices in three areas; it means the method can distinguish different areas' markets from the phylogenetic trees. The results show that we can get satisfactory information from financial markets by this method. The information categorization method can not only be used in physiologic time series, but also in financial time series.

  12. Magnon drag thermopile

    NASA Astrophysics Data System (ADS)

    Valenzuela, Sergio O.

    2013-03-01

    Thermoelectric effects in spintronics are gathering increasing attention as a means of controlling spin information by using heat flow. Thermal magnons (spin-wave quanta) are expected to play a major role, however, the coupling between electrons and magnons in ferromagnetic metals remains poorly understood. We demonstrate a conceptually new device that enables us to gather information on magnon-electron scattering and magnon-drag effects. The device resembles a thermopile formed by a large number of pairs of ferromagnetic wires placed between a hot and a cold source and connected thermally in parallel and electrically in series. By controlling the relative orientation of the magnetization in pairs of wires, the magnon drag can be studied independently of the electron and phonon drag thermoelectric effects. Measurements as a function of temperature reveal the effect on magnon drag following a variation of magnon and phonon populations. These results demonstrate the feasibility of directly converting magnon dynamics of nanomagnets into an electrical signal and could pave the way to novel thermoelectric devices for energy harvesting. This research was supported by the Spanish Ministerio de Ciencia e Innovación, MICINN (MAT2010-18065) and by the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement NANOFUNCTION no 257375.

  13. Magnetic edge states and mixed-parity pairing in spin-triplet superconductors

    NASA Astrophysics Data System (ADS)

    Cuoco, Mario; Gentile, Paola; Noce, Canio; Vekhter, Ilya; Romano, Alfonso

    2014-03-01

    We show that a spontaneous magnetic moment may appear at the edge of a spin-triplet superconductor if the system allows for pairing in a subdominant channel and non-uniform spatial profile. To unveil the microscopic mechanism behind such effect we combine numerical solution of the Bogoliubov-De Gennes equations for a tight-binding model with nearest-neighbor attraction, and the symmetry based Ginzburg-Landau approach. We find that a modulation of the electronic density near the edge of the system leads to a non-unitary superconducting state where spin-singlet pairing coexists with the dominant triplet superconducting order. We demonstrate that the spin polarization at the edge appears due to the inhomogeneity of the non-unitary state and originates in the lifting of the spin-degeneracy of the Andreev bound-states. For chiral spin-triplet superconductors spin current flows along the interface and surface charge currents exhibit anomalous dependence on the magnetization. - A. Romano, P. Gentile, C. Noce, I. Vekhter, M. Cuoco, Phys. Rev. Lett. 110, 267002 (2013). This research has received funding from the EU -FP7/2007-2013 under grant agreement N. 264098 - MAMA, and was supported in part by US NSF via Grant No. DMR-1105339

  14. Observed evidence of the anomalous South China Sea western boundary current during the summers of 2010 and 2011

    NASA Astrophysics Data System (ADS)

    Shu, Yeqiang; Xue, Huijie; Wang, Dongxiao; Xie, Qiang; Chen, Ju; Li, Jian; Chen, Rongyu; He, Yunkai; Li, Daning

    2016-02-01

    Seven years of directly measured current data from a mooring in the Xisha area of the South China Sea (SCS), together with shipboard ADCP and satellite data, have shown the western boundary current (WBC) anomaly and its vertical structure during the summers of 2010 and 2011. The observed WBC presented obvious year-to-year variability, especially in the summer. Overall, the summer mean velocity at the mooring site over 7-year (2007-2013) was northeastward. The moored ADCP showed that the northeastward velocity was particularly strong in the summer of 2010, but the increase was confined in the upper 120 m. In contrast, the northeastward current disappeared throughout the observed depth range (from 50 to 450 m) in the summer of 2011. Even at the deepest observed position, the monthly velocity anomalies reached 14 cm s-1 westward and 12 cm s-1 southward in the zonal and meridional directions, respectively. Both the Vietnam offshore current (VOC) and double gyres in the western SCS disappeared and the southern anticyclonic gyre expanded to strengthened the northward WBC in the summer of 2010. However, in summer of 2011, the VOC intensified, and the northern cyclonic gyre enlarged with its northern edge reaching 18°N, slightly north of mooring site, which weakened the northeastward WBC. The observed SCS circulation anomalies during 2010 and 2011 were mainly induced by the basin-scale wind field anomalies associated with the 2009/2010 El Niño and 2010/2011 La Niña.

  15. Addressing health inequalities by using Structural Funds. A question of opportunities.

    PubMed

    Neagu, Oana Maria; Michelsen, Kai; Watson, Jonathan; Dowdeswell, Barrie; Brand, Helmut

    2017-03-01

    Making up a third of the EU budget, Structural and Investment Funds can provide important opportunities for investing in policies that tackle inequalities in health. This article looks back and forward at the 2007-2013 and 2014-2020 financial periods in an attempt to inform the development of health equity as a strand of policy intervention under regional development. It combines evidence from health projects funded through Structural Funds and a document analyses that locates interventions for health equity under the new regulations. The map of opportunities has changed considerably since the last programming period, creating more visibility for vulnerable groups, social determinants of health and health systems sustainability. As the current programming period is progressing, this paper contributes to maximizing this potential but also identifying challenges and implementation gaps for prospective health system engagement in pursuing health equity as part of Structural Funds projects. The austerity measures and their impact on public spending, building political support for investments as well as the difficulties around pursuing health gains as an objective of other policy areas are some of the challenges to overcome. European Structural and Investment Funds could be a window of opportunity that triggers engagement for health equity if sectors adopt a transformative approach and overcome barriers, cooperate for common goals and make better use of the availability of these resources.

  16. Climatological analysis of the real-time NSSL 4km WRF-ARW

    NASA Astrophysics Data System (ADS)

    Goines, D. C.; Kennedy, A. D.

    2014-12-01

    In recent years, the Weather Research and Forecasting (WRF) model has been used for dynamic downscaling ofGlobal Climate Models (GCMs) to forecast smaller scale phenomena that GCMs cannot resolve at coarseresolutions. High resolution convection-allowing (CA) WRF simulations have gained popularity in recent yearsdue to their ability to resolve the structure of high impact phenomena such as topographically inducedprecipitation, mesoscale convective systems, and supercell thunderstorms. An accurate representation of theseextreme events is important for climate mitigation and adaptation strategies by policy makers. With the usage ofdownscaling and fine resolutions of WRF simulations becoming more recurrent, the question still remains: dohigh resolution CA WRF simulations correctly represent climatological precipitation? This study examines theclimatology of precipitation over the U.S. Central Plains produced for 7 years (2007-2013) by the NationalSevere Storms Laboratory (NSSL) high resolution (4km) CA WRF model. Precipitation forecasts for variousforecast hours are analyzed to determine whether the model climatology is similar to observations. TheMeteorological Evaluation Tool (MET) Method for Object-Based Diagnostic Evaluation (MODE) is utilized tocompare the precipitation forecasts to observations. The National Centers for Environmental Prediction (NCEP)Stage IV multi-sensor precipitation analysis is used as the truth for model assessment. Model performance isinvestigated for a variety of synoptic regimes using self-organizing maps (SOMs).

  17. The role of maternal age in twin pregnancy outcomes.

    PubMed

    McLennan, Amelia S; Gyamfi-Bannerman, Cynthia; Ananth, Cande V; Wright, Jason D; Siddiq, Zainab; D'Alton, Mary E; Friedman, Alexander M

    2017-07-01

    There are limited data on how maternal age is related to twin pregnancy outcomes. The purpose of this study was to assess the relationship between maternal age and risk for preterm birth, fetal death, and neonatal death in the setting of twin pregnancy. This population-based study of US birth, fetal death, and period-linked birth-infant death files from 2007-2013 evaluated neonatal outcomes for twin pregnancies. Maternal age was categorized as 15-17, 18-24, 25-29, 30-34, 35-39, and ≥40 years of age. Twin live births and fetal death delivered at 20-42 weeks were included. Primary outcomes included preterm birth (<34 weeks and <37 weeks), fetal death, and neonatal death at <28 days of life. Analyses of preterm birth at <34 and <37 weeks were adjusted for demographic and medical factors, with maternal age modeled with the use of restricted spline transformations. A total of 955,882 twin live births from 2007-2013 were included in the analysis. Preterm birth rates at <34 and <37 weeks gestation were highest for women 15-17 years of age, decreased across subsequent maternal age categories, nadired for women 35-39 years old, and then increased slightly for women ≥40 years old. Risk for fetal death generally decreased across maternal age categories. Risk for fetal death was 39.9 per 1000 live births for women 15-17 years old, 24.2 for women 18-24 years old, 17.8 for women 25-29 years old, 16.4 for women 30-34 years old, 17.2 for women 35-39 years old, and 15.8 for women ≥40 years old. Risk for neonatal death at <28 days was highest for neonates born to women 15-17 years old (10.0 per 1,000 live births), decreased to 7.3 for women 18-24 years old and 5.5 for women 25-29 years old and ranged from 4.3-4.6 for all subsequent maternal age categories. In adjusted models, risk for preterm birth at <34-<37 weeks gestation was not elevated for women in their mid-to-late 30s; however, risk was elevated for women <20 years old and increased progressively with age for women

  18. The utility of pulmonary function testing in predicting outcomes following liver transplantation.

    PubMed

    Kia, Leila; Cuttica, Michael J; Yang, Amy; Donnan, Erica N; Whitsett, Maureen; Singhvi, Ajay; Lemmer, Alexander; Levitsky, Josh

    2016-06-01

    Although pulmonary function tests (PFTs) are routinely performed in patients during the evaluation period before liver transplantation (LT), their utility in predicting post-LT mortality and morbidity outcomes is not known. The aim of this study was to determine the impact of obstructive and/or restrictive lung disease on post-LT outcomes. We conducted a retrospective analysis of patients who had pre-LT PFTs and underwent a subsequent LT (2007-2013). We used statistical analyses to determine independent associations between PFT parameters and outcomes (graft/patient survival, time on ventilator, and hospital/intensive care unit [ICU] length of stay [LOS]). A total of 415 LT recipients with available PFT data were included: 65% of patients had normal PFTs; 8% had obstructive lung disease; and 27% had restrictive lung disease. There was no difference in patient and graft survival between patients with normal, obstructive, and restrictive lung disease. However, restrictive lung disease was associated with longer post-LT time on ventilator and both ICU and hospital LOS (P < 0.05). More specific PFT parameters (diffusing capacity of the lungs for carbon monoxide, total lung capacity, and residual volume) were all significant predictors of ventilator time and both ICU and hospital LOS (P < 0.05). Although pre-LT PFT parameters may not predict post-LT mortality, restrictive abnormalities correlate with prolonged post-LT ventilation and LOS. Efforts to identify and minimize the impact of restrictive abnormalities on PFTs might improve such outcomes. Liver Transplantation 22 805-811 2016 AASLD.

  19. Diurnal variations in water vapor over Central and South America

    NASA Astrophysics Data System (ADS)

    Meza, Amalia; Mendoza, Luciano; Bianchi, Clara

    2016-07-01

    Diurnal variations in atmospheric integrated water vapor (IWV) are studied employing IWV estimates, with a 30 minutes sampling rate, derived from Global Navigation Satellite Systems (GNSS) observations during the period 2007-2013. The analysis was performed in 73 GNSS tracking sites (GPS + GLONASS) which have more than 5 years of data. The selected area involves different climate types, from polar to tropical, with different diurnal variations of the integrated total humidity content. There are many processes that could induce diurnal variations in atmospheric water vapor (Dai et al, 1999 a,b), the most relevant causes are: surface evapotranspiration, atmospheric large-scale vertical motion, atmospheric low-level moisture convergence and precipitation and vertical mixing (which affects the vertical distribution of water vapor but does not affect the IWV). The numerical tools, Singular Value Decomposition and classical Multidimensional Scaling methods, are used to study these variations, considering the measurements made at each stations, as sample in the analysis. The aim of this investigation is to identify the IWV variability with respect to the local time associated to the different climate regions. In order to improve our analysis, all available weather information, such as radiosondes measurements (which are few), measurements of pressure and temperature and Numerical Weather Models reanalysis data, are used. Reference: Dai, A., K. E. Trenberth, and T. R. Karl, 1999 a: Effects of clouds, soil moisture, precipitation and water vapor on diurnal temperature range. J. Climate, 12, 2451-2473. Dai, A., F. Giorgi, and K. E. Trenberth, 1999 b: Observed and model simulated precipitation diurnal cycle over the contiguous United States.J. Geophys. Res., 104, 6377-6402. KEYWORDS: water vapor, diurnal cycle, GNSS

  20. A new method for assessing surface solar irradiance: Heliosat-4

    NASA Astrophysics Data System (ADS)

    Qu, Z.; Oumbe, A.; Blanc, P.; Lefèvre, M.; Wald, L.; Schroedter-Homscheidt, M.; Gesell, G.

    2012-04-01

    Downwelling shortwave irradiance at surface (SSI) is more and more often assessed by means of satellite-derived estimates of optical properties of the atmosphere. Performances are judged satisfactory for the time being but there is an increasing need for the assessment of the direct and diffuse components of the SSI. MINES ParisTech and the German Aerospace Center (DLR) are currently developing the Heliosat-4 method to assess the SSI and its components in a more accurate way than current practices. This method is composed by two parts: a clear sky module based on the radiative transfer model libRadtran, and a cloud-ground module using two-stream and delta-Eddington approximations for clouds and a database of ground albedo. Advanced products derived from geostationary satellites and recent Earth Observation missions are the inputs of the Heliosat-4 method. Such products are: cloud optical depth, cloud phase, cloud type and cloud coverage from APOLLO of DLR, aerosol optical depth, aerosol type, water vapor in clear-sky, ozone from MACC products (FP7), and ground albedo from MODIS of NASA. In this communication, we briefly present Heliosat-4 and focus on its performances. The results of Heliosat-4 for the period 2004-2010 will be compared to the measurements made in five stations within the Baseline Surface Radiation Network. Extensive statistic analysis as well as case studies are performed in order to better understand Heliosat-4 and have an in-depth view of the performance of Heliosat-4, to understand its advantages comparing to existing methods and to identify its defaults for future improvements. The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under Grant Agreement no. 218793 (MACC project) and no. 283576 (MACC-II project).

  1. Influence of hydrodynamic parameters on tsunami run-up uncertainty induced by earthquake random slip distribtutions

    NASA Astrophysics Data System (ADS)

    Løvholt, Finn; Kim, Jihwan; Pedersen, Geir; Harbitz, Carl

    2016-04-01

    The standard approach in forward modeling of earthquake tsunamis usually assume a uniform slip pattern. This is assumption is used both in deterministic and probabilistic models. However, the slip distribution for an earthquake is subject to (aleatory) uncertainty, and consequently the induced tsunami run-up will have an uncertainty range even given the same moment magnitude and hypocentre earthquake location. Here, we present studies of run-up variability due to stochastic earthquake slip variation in both two and three dimensions. The approach taken is fully idealized, although we draw upon the experience from two of the most destructive events the last hundred years, namely the Mw8 1976 Moro Gulf earthquake and tsunami as well as the Mw9 2011 Tohoku earthquake tsunami. The former event is used to design the two-dimensional stochastic simulations, and the latter event the three-dimensional simulations. Our primary focus is not reproduce past run-up, but rather to investigate how the hydrodynamics influence uncertainty. These quantities include among others the non-hydrodynamic response during generation, frequency dispersion, friction from the seabed, and wave-breaking. We simulate tsunamis for an ensemble of synthetic random slip over an idealized shelf geometry broken into linear segments. The uncertainty propagation from source to run-up for the two different cases are discussed and compared. As demonstrated, both the dimensionality and the earthquake parameters influence the contributions of the hydrodynamic parameters on the uncertainty. Further work will be needed to explore the transitional behaviour between the two very different cases displayed here. The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement 603839 (Project ASTARTE).

  2. Glasses: Hiding or causing skin cancer?

    PubMed

    Zhang, Ze; Behshad, Soroosh; Sethi-Patel, Pooja; Valenzuela, Alejandra A

    2016-10-01

    This article evaluates malignant transformation of lesions presenting in the periocular skin under the eye spectacle nose pad. A non-comparative retrospective chart review of clinical features and pathological findings of patients presenting with periocular malignancies in the exact vicinity where the nose pads of their eye spectacles rested was completed. The study took place in one tertiary oculoplastic referral center between 2007-2013. Ten patients were included, six of whom were male. All subjects wore eye spectacles while awake for at least 15 years, and had an evident suspicious lesion in the exact area that coincided with the resting place of the nose pad. The mean age was 73.5 years (range 65-85 years) and all patients had the lesion present for at least one year. Most cases were squamous skin malignancies (five squamous cell carcinomas [SCC], 2 intra-epidermal carcinomas [IEC], while 3 basal cell carcinomas [BCC]). Treatment involved surgical excision of the lesion with frozen section for margin control and reconstruction with a myocutaneous flap. Periocular malignancies of the inferior medial canthal area, where the nose pad of eye spectacle places pressure, can be easily missed or misdiagnosed. Marjolin ulcers (MU) classically present as an aggressive SCC in area of chronic inflammation, which has been previously correlated to constant pressure, repetitive trauma, or non-healing wounds in other areas of the body. We propose that the traumatic chronic pressure in the infero-medial canthal region from long-term eye spectacle nose pad use, may induce poor lymphatic regeneration leading to an immune system deficiency that predisposes this skin to a malignant transformation. The presence of chronic eye spectacle nose pads also prevents proper and timely detection of such malignancies. Complete excision of these lesions with margin control, adequate follow-up for possible recurrence, and surveillance for new lesions on the patient's contralateral side, is

  3. A Time Series Model for Assessing the Trend and Forecasting the Road Traffic Accident Mortality

    PubMed Central

    Yousefzadeh-Chabok, Shahrokh; Ranjbar-Taklimie, Fatemeh; Malekpouri, Reza; Razzaghi, Alireza

    2016-01-01

    Background Road traffic accident (RTA) is one of the main causes of trauma and known as a growing public health concern worldwide, especially in developing countries. Assessing the trend of fatalities in the past years and forecasting it enables us to make the appropriate planning for prevention and control. Objectives This study aimed to assess the trend of RTAs and forecast it in the next years by using time series modeling. Materials and Methods In this historical analytical study, the RTA mortalities in Zanjan Province, Iran, were evaluated during 2007 - 2013. The time series analyses including Box-Jenkins models were used to assess the trend of accident fatalities in previous years and forecast it for the next 4 years. Results The mean age of the victims was 37.22 years (SD = 20.01). From a total of 2571 deaths, 77.5% (n = 1992) were males and 22.5% (n = 579) were females. The study models showed a descending trend of fatalities in the study years. The SARIMA (1, 1, 3) (0, 1, 0) 12 model was recognized as a best fit model in forecasting the trend of fatalities. Forecasting model also showed a descending trend of traffic accident mortalities in the next 4 years. Conclusions There was a decreasing trend in the study and the future years. It seems that implementation of some interventions in the recent decade has had a positive effect on the decline of RTA fatalities. Nevertheless, there is still a need to pay more attention in order to prevent the occurrence and the mortalities related to traffic accidents. PMID:27800467

  4. Nutrition, environment and cardiovascular health (NESCAV): protocol of an inter-regional cross-sectional study

    PubMed Central

    2010-01-01

    Background Despite the remarkable technological progress in health care and treatment, cardiovascular disease remains the leading cause of premature death, prolonged hospitalization and disability in most European countries. In the population of the Greater Region (Grand-Duchy of Luxembourg, Wallonia in Belgium, and Lorraine in France), the prevalence of cardiovascular risk factors and disease is among the highest in Europe, warranting the need for a better understanding of factors contributing to this pattern. In this context, the cross-border "Nutrition, Environment and Cardiovascular Health-NESCAV" project is initiated by an inter-regional multi-disciplinary consortium and supported by the INTERREG IV A program "Greater Region", 2007-2013, to fight synergically and harmoniously against this major public health problem. Methods/design The objectives of the three-year planned project are to assess, in a representative sample of 3000 randomly selected individuals living at the Greater Region, 1) the cardiovascular health and risk profile, 2) the association between the dietary habits and the cardiovascular risk, 3) the association of occupational and environmental pollution markers with the cardiovascular risk, 4) the knowledge, awareness and level of control of cardiovascular risk factors, 5) the potential gaps in the current primary prevention, and finally, to address evidence-based recommendations enabling the development of inter-regional guidance to help policy-makers and health care workers for the prevention of cardiovascular disease. Discussion The findings will provide tools that may enable the Greater Region's decision-makers and health professionals to implement targeted and cost-effective prevention strategies. PMID:21078172

  5. Characterization of the Temporal-Spatial Variability of Trans-Atlantic Dust Transport Based on CALIPSO Lidar Measurements

    NASA Technical Reports Server (NTRS)

    Yu, Hongbin

    2015-01-01

    The trans-Atlantic dust transport has important implications for human and ecosystem health, the terrestrial and oceanic biogeochemical cycle, weather systems, and climate. A reliable assessment of these influences requires the characterization of dust distributions in three dimensions and over long time periods. We provide an observation-based multiyear estimate of trans-Atlantic dust transport by using a 7-year (2007 - 2013) lidar record from the Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO) in both cloud-free and above-cloud conditions. We estimate that on a basis of the 7-year average and integration over 10S - 30N, 182 Tg a-1 dust leaves the coast of North Africa at 15W, of which 132 Tg a-1 and 43 Tg a-1 reaches 35W and 75W, respectively. These flux estimates have an overall known uncertainty of (45 - 70). The 7-year average of dust deposition into the Amazon Basin is estimated to be 28 (8 - 48) Tg a-1 or 29 (8 - 50) kg ha-1 a-1. This imported dust could provide about 0.022 (0.006 - 0.037) Tg P of phosphorus per year, equivalent to 23 (7 - 39) g P ha-1 a-1 to fertilize the Amazon rainforest, which is comparable to the loss of phosphorus to rainfall. Significant seasonal variations are observed in both the magnitude of total dust transport and its meridional and vertical distributions. The observed large interannual variability of annual dust transport is highly anti-correlated with the prior-year Sahel Precipitation Index. Comparisons of CALIPSO measurements with surface-based observations and model simulations will also be discussed.

  6. Impact of antifungal prescription on relative distribution and susceptibility of Candida spp. - Trends over 10 years.

    PubMed

    Bailly, Sébastien; Maubon, Danièle; Fournier, Pierre; Pelloux, Hervé; Schwebel, Carole; Chapuis, Claire; Foroni, Luc; Cornet, Muriel; Timsit, Jean-François

    2016-01-01

    The incidence of Candida spp. infections is worrisome, particularly in critically ill patients. Previous reports suggested that increasing use of antifungal therapy might affect resistance profiles of invasive strains. The study objective was to describe the distribution resistance profile of Candida spp. strains, and to correlate it with antifungal consumptions within one ICU. Antifungal drug consumption was measured as the number of defined daily doses per 1000 hospital days. The distribution of Candida spp. over a 10 year period 2004-2013 and the MICs of antifungal drugs over 2007-2013 were determined. Time series analyses were performed. Of 2403 identified Candida spp. from 5360 patients, Candida albicans predominated (53.1%), followed by Candida glabrata (16.2%), Candida parapsilosis (7.9%) and Candida tropicalis (7.5%). C. parapsilosis increased from 5.7% in 2004 to 8.4% in 2013 (P = 0.02). The increase in caspofungin use is correlated with the increase in caspofungin MICs of C. parapsilosis (P = 0.01), C. glabrata (P = 0.001) and C. albicans (P = 0.02). Polyenes consumption correlated with an increase in amphotericin B MICs of C. glabrata (P = 0.04). Previous history of antifungal prescription within an ICU influences Candida species distribution and susceptibility profile to antifungal agents. The significant selective pressure exerted by caspofungin and amphotericin B on C. glabrata is a concern. Copyright © 2015 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

  7. Assessment of Digital Terrain Model algorithms for the development of a massive processing system for all high-resolution stereo images of Mars from CTX and HiRISE

    NASA Astrophysics Data System (ADS)

    Yershov, Vladimir; Ivanov, Anton; Muller, Jan-Peter; Tao, Yu; Mr; Pool, William; Kim, Jung-Rack; Sidiropoulos, Panagiotis

    We assess several algorithms for generating digital terrain models (DTM) of Mars using high-resolution stereoscopic images produced by the High Resolution Imaging Science Experiment (HiRISE) camera and Context Camera (CTX) onboard the NASA Mars Reconnaissance Orbiter (MRO) spacecraft. One of the algorithms was developed jointly by University of Seoul and University College London and uses a stereo processing chain based on a non-rigorous sensor model with geodetic control derived from a reference stereo data source (HRSC co-registered to MOLA). The second algorithm was developed at École Polytechnique Federale de Lausanne on the basis of the Integrated Software for Images and Spectrometers (ISIS) application programme interface for deriving ray information and ray intersection points corresponding to the matched pixels of two images forming a stereo pair. The quality assessment of image photogrammetric registration of these two algorithms is made by using reference (“true”) data generated by USGS using SOCET® and using the NASA Ames pipeline and for limited areas using DTMs from re-projected and ortho-rectified images obtained on the Martian surface by Mars Exploration Rovers A and B within the EU-FP7-PROViDE project. The latter images were produced at University College London by a different software designed for stereo-matching rover images. The quality assessment of two DTM-building algorithms is made within the iMars project of the European Seventh Framework Programme. Acknowledgements: The research leading to these results has received funding from the European Union’s Seventh Framework Programme (FP7/2007-2013) under iMars grant agreement n˚ 607379, PRoViDE grant agreement n˚ 312377 and partial funding for PS from the STFC “MSSL Consolidated Grant” ST/K000977/1.

  8. Health Correlates of Criminal Justice Involvement in 4,793 Transgender Veterans.

    PubMed

    Brown, George R; Jones, Kenneth T

    2015-12-01

    Transgender (TG) persons are overrepresented in prison settings and in the U.S. veteran population. Health disparities studies of large populations of transgender people involved with the criminal justice system have not been published to date. We studied a large cohort of TG veterans who received care in Veterans Health Administration (VHA) facilities during 2007-2013 (n = 4,793) and a 3:1 matched control group of veterans without known TG identification (n = 13,625). Three hundred twenty six (n = 138 TG, 188 non-TG) had received VHA services in programs designed to address the needs of justice involved (JI) veterans. We linked patients in each of the three groups to their medical and administrative data. TG veterans were more likely to be justice involved than controls (2.88% vs. 1.38%; P < .0001). Compared to non-TG JI veterans, TG JI veterans were more likely to have a history of homelessness (80% vs. 67%; P < .05) and to have reported sexual trauma while serving in the military (23% vs. 12%; P < .01). Significant health disparities were noted for TG JI veterans for depression, hypertension, obesity, posttraumatic stress disorder, serious mental illness, and suicidal ideation/attempts. These data suggest that TG veterans experience a number of health risks compared to non-TG veterans, including an increased likelihood of justice involvement. TG veterans involved with the criminal justice system are a particularly vulnerable group and services designed to address the health care needs of this population, both while incarcerated and when in the community, should take these findings into account in the development of health screenings and treatment plans.

  9. The Fertilizing Role of African Dust in the Amazon Rainforest: A First Multiyear Assessment Based on CALIPSO Lidar Observations

    NASA Technical Reports Server (NTRS)

    Yu, Hongbin; Chin, Mian; Yuan, Tianle; Bian, Huisheng; Remer, Lorraine A.; Prospero, Joseph M.; Omar, Ali; Winker, David; Yang, Yuekui; Zhang, Yan; hide

    2015-01-01

    The productivity of the Amazon rainforest is constrained by the availability of nutrients, in particular phosphorus (P). Deposition of long-range transported African dust is recognized as a potentially important but poorly quantified source of phosphorus. This study provides a first multiyear satellite-based estimate of dust deposition into the Amazon Basin using three dimensional (3D) aerosol measurements over 2007-2013 from the Cloud-Aerosol Lidar with Orthogonal Polarization (CALIOP). The 7-year average of dust deposition into the Amazon Basin is estimated to be 28 (8 to approximately 48) Tg a(exp -1) or 29 (8 to approximately 50) kg ha(exp -1) a(exp -1). The dust deposition shows significant interannual variation that is negatively correlated with the prior-year rainfall in the Sahel. The CALIOP-based multi-year mean estimate of dust deposition matches better with estimates from in-situ measurements and model simulations than a previous satellite-based estimate does. The closer agreement benefits from a more realistic geographic definition of the Amazon Basin and inclusion of meridional dust transport calculation in addition to the 3D nature of CALIOP aerosol measurements. The imported dust could provide about 0.022 (0.0060.037) Tg P of phosphorus per year, equivalent to 23 (7 to approximately 39) g P ha(exp -1) a(exp -1) to fertilize the Amazon rainforest. This out-of-Basin P input largely compensates the hydrological loss of P from the Basin, suggesting an important role of African dust in preventing phosphorus depletion on time scales of decades to centuries.

  10. Improving Sea Water Quality Monitoring by Integrating Satellite, Aerial and Ground based Multispectral Observations in the optical band: the case of Ionian Sea along Basilicata (Italy) coasts

    NASA Astrophysics Data System (ADS)

    Lacava, T.; Ciancia, E.; Coviello, I.; Daraio, M.; Paciello, R.; Pergola, N.; Pignatti, S.; Santini, F.; Tramutoli, V.; Vallianatos, F.

    2012-12-01

    Ocean color satellite instruments provide information both on sea surface optical variables (e.g. upwelling normalized water-leaving radiances) and on bio-optical parameters, such as chlorophyll-a concentration, Cromophormic Dissolved Organic Matter (C-DOM) concentration, etc. A study of these parameters and of their evolution in the space-time domain may provide useful information on the overall quality of the sea water for a specific area offering, in addition, the reference behaviors necessary for identifying significant (possibly induced by anthropic pressure) changes in the coastal environment. In this context main aim of IOSMOS (IOnian Sea water quality MOnitoring by Satellite data) - a Project for European Transnational Cooperation co financed by the Operational Programme ERDF Basilicata 2007-2013 - is the development of advanced satellite products and techniques for the study and monitoring of Ionian sea water quality in terms of bio-optical properties along Basilicata (Italy) coasts. Specific goals of the project are: i) identification, tuning and assessment of advanced satellite products useful for the estimation of parameters relevant for the bio-optical characterization of the coastal waters quality; ii) identification, tuning and assessment of advanced satellite products useful for the study of sediment transport mechanisms into the sea; iii) analysis of long-term trends (up to 15 years) to identify the most exposed areas, those at highest degradation and/or greatest potential risk. On the base of airborne and in situ calibration campaigns different literature (single-image) algorithms will be validated and their results compared with original techniques based on multi-temporal satellite data analyses. In this paper main starting points and preliminary results of the IOSMOS project will be presented.

  11. Transit timing of TrES-2: a combined analysis of ground- and space-based photometry

    NASA Astrophysics Data System (ADS)

    Raetz, St.; Maciejewski, G.; Ginski, Ch.; Mugrauer, M.; Berndt, A.; Eisenbeiss, T.; Adam, Ch.; Raetz, M.; Roell, T.; Seeliger, M.; Marka, C.; Vaňko, M.; Bukowiecki, Ł.; Errmann, R.; Kitze, M.; Ohlert, J.; Pribulla, T.; Schmidt, J. G.; Sebastian, D.; Puchalski, D.; Tetzlaff, N.; Hohle, M. M.; Schmidt, T. O. B.; Neuhäuser, R.

    2014-10-01

    Homogeneous observations and careful analysis of transit light curves can lead to the identification of transit timing variations (TTVs). TrES-2 is one of few exoplanets, which offer the matchless possibility to combine long-term ground-based observations with continuous satellite data. Our research aimed at the search for TTVs that would be indicative of perturbations from additional bodies in the system. We also wanted to refine the system parameters and the orbital elements. We obtained 44 ground-based light curves of 31 individual transit events of TrES-2. Eight 0.2-2.2-m telescopes located at six observatories in Germany, Poland and Spain were used. In addition, we analysed 18 quarters (Q0-Q17) of observational data from NASA's space telescope Kepler including 435 individual transit events and 11 publicly available ground-based light curves. Assuming different limb darkening (LD) laws we performed an analysis for all light curves and redetermined the parameters of the system. We also carried out a joint analysis of the ground- and space-based data. The long observation period of seven years (2007-2013) allowed a very precise redetermination of the transit ephemeris. For a total of 490 transit light curves of TrES-2, the time of transit mid-point was determined. The transit times support neither variations on long time-scale nor on short time-scales. The nearly continuous observations of Kepler show no statistically significant increase or decrease in the orbital inclination i and the transit duration D. Only the transit depth shows a slight increase which could be an indication of an increasing stellar activity. In general, system parameters obtained by us were found to be in agreement with previous studies but are the most precise values to date.

  12. (18)F-FDG PET/CT in follow-up evaluation in pediatric patients with Langerhans histiocytosis.

    PubMed

    Garcia, J R; Riera, E; Bassa, P; Mourelo, S; Soler, M

    We evaluated the impact of (18)F-FDG PET/CT in identifying sites of active disease and to assess therapeutic follow up in a group of pediatric patients with Langerhans cell histiocytosis (LCH). During 2007-2013, 13 (18)F-FDG PET/CT studies were performed for follow-up in 7 patients with a diagnosis of LCH (4 female, 3 male; 1-12 years-old). PET findings were analyzed and correlated with the CT and MRI. Findings were also follow-up by these techniques. PET was negative in 4 patients (all diagnosed with bone lesions and one with pituitary involvement also). CT findings showed residual morphological bone lesions in all patients, and hypophysis MRI study showed no abnormal signal. PET remained negative at 10, 14, 25 and 28 months, and no new lesions on CT and MRI were detected. PET was positive in 3 patients (one with cervical lymphadenopathy and 2 with bone lesions, one also with pituitary involvement not identified by PET). CT findings showed pathological cervical lymphadenopathy (n=1), bone lesions (n=2) and also a pituitary MRI lesion (n=1). In a patient with cervical lymphadenopathy histology demonstrated LCH involvement. In the other 2 patients, PET remained positive with an increase of (18)F-FDG bone uptake at 17 and 19 months. In our preliminar study, (18)F-FDG PET is a useful imaging procedure, along with other diagnostic tools, for identification of active lesions. Copyright © 2017 Elsevier España, S.L.U. y SEMNIM. All rights reserved.

  13. A Renormalization-Group Interpretation of the Connection between Criticality and Multifractals

    NASA Astrophysics Data System (ADS)

    Chang, Tom

    2014-05-01

    Turbulent fluctuations in space plasmas beget phenomena of dynamic complexity. It is known that dynamic renormalization group (DRG) may be employed to understand the concept of forced and/or self-organized criticality (FSOC), which seems to describe certain scaling features of space plasma turbulence. But, it may be argued that dynamic complexity is not just a phenomenon of criticality. It is therefore of interest to inquire if DRG may be employed to study complexity phenomena that are distinctly more complicated than dynamic criticality. Power law scaling generally comes about when the DRG trajectory is attracted to the vicinity of a fixed point in the phase space of the relevant dynamic plasma parameters. What happens if the trajectory lies within a domain influenced by more than one single fixed point or more generally if the transformation underlying the DRG is fully nonlinear? The global invariants of the group under such situations (if they exist) are generally not power laws. Nevertheless, as we shall argue, it may still be possible to talk about local invariants that are power laws with the nonlinearity of transformation prescribing a specific phenomenon as crossovers. It is with such concept in mind that we may provide a connection between the properties of dynamic criticality and multifractals from the point of view of DRG (T. Chang, Chapter VII, "An Introduction to Space Plasma Complexity", Cambridge University Press, 2014). An example in terms of the concepts of finite-size scaling (FSS) and rank-ordered multifractal analysis (ROMA) of a toy model shall be provided. Research partially supported by the US National Science Foundation and the European Community's Seventh Framework Programme (FP7/ 2007-2013) under Grant agreement no. 313038/STORM.

  14. Should first-line empiric treatment strategies cover coagulase-negative staphylococcal infections in severely malnourished or HIV-infected children in Kenya?

    PubMed

    Obiero, Christina W; Seale, Anna C; Jones, Kelsey; Ngari, Moses; Bendon, Charlotte L; Morpeth, Susan; Mohammed, Shebe; Mturi, Neema; Fegan, Greg; Berkley, James A

    2017-01-01

    Bloodstream infection is a common cause of morbidity in children aged <5 years in developing countries. In studies reporting bacteremia in Africa, coagulase-negative Staphylococci (CoNS) are commonly isolated. However, it is currently unclear whether children who are highly susceptible to infection because of severe acute malnutrition (SAM) or HIV should be treated with antimicrobials specifically to cover CoNS. We aimed to determine the clinical significance of CoNS amongst children admitted to a rural hospital in Kenya in relation to nutritional and HIV status. Systematically collected clinical and microbiological surveillance data from children aged 6-59 months admitted to Kilifi County Hospital (2007-2013) were analysed. Multivariable regression was used to test associations between CoNS isolation from blood cultures and SAM (MUAC <11.5cm or nutritional oedema (kwashiorkor)), and HIV serostatus; and among children with SAM or HIV, associations between CoNS isolation and mortality, duration of hospitalization and clinical features. CoNS were isolated from blood culture in 906/13,315 (6.8%) children, of whom 135/906 (14.9%) had SAM and 54/906 (6.0%) were HIV antibody positive. CoNS isolation was not associated with SAM (MUAC<11.5cm (aOR 1.11, 95% CI 0.88-1.40) or kwashiorkor (aOR 0.84, 95% CI 0.48-1.49)), or a positive HIV antibody test (aOR 1.25, 95% CI 0.92-1.71). Among children with SAM or a positive HIV antibody test, CoNS isolation was not associated with mortality or prolonged hospitalization. In a large, systematic study, there was no evidence that antimicrobial therapy should specifically target CoNS amongst children with SAM or HIV-infection or exposure.

  15. The ASTARTE Paleotsunami and Mass Transport Deposits data bases - web-based references for tsunami and submarine landslide research around Europe

    NASA Astrophysics Data System (ADS)

    De Martini, Paolo Marco; Patera, Antonio; Orefice, Simone; Paris, Raphael; Völker, David; Lastras, Galderic; Terrinha, Pedro; Noiva, João; Smedile, Alessandra; Pantosti, Daniela; Hunt, James; Gutscher, Marc-Andre; Migeon, Sébastien; Papadopoulos, Gerassimos; Triantafyllou, Ioanna; Yalciner, Ahmet C.

    2017-04-01

    EU project ASTARTE aims at developing a higher level of tsunami hazard assessment in the North East Atlantic, Mediterranean and Connected seas (NEAM) region by a combination of field work, experimental work, numerical modeling and technical development. The project is a cooperative work of 26 institutes from 16 countries and links together the description of past tsunamigenic events, the identification and characterization of tsunami sources, the calculation of the impact of such events, and the development of adequate resilience and risks mitigation strategies (www.astarte.eu). Within ASTARTE two web-based data bases on Paleotsunami and Mass Transport Deposits in the NEAM areas were created with the purpose to be the future information repositories for tsunami research in Europe.The aim is to integrate every existing official scientific reports and peer reviewed papers on these topics and update on new entries every 6-12 months, hosting information and detailed data, that are crucial e.g for tsunami modeling. A relational database managed by ArcGIS for Desktop 10.x software has been implemented. One of the final goals of the project is the public sharing of the archived datasets through a web-based map service that will allow visualizing, querying, analyzing, and interpreting all datasets. The interactive map service will be hosted by ArcGIS Online and will deploy the cloud capabilities of the portal. Any interested users will be able to access the online GIS resources through any Internet browser or specific apps that run on desktop machines, smartphones, or tablets and will be able to use the analytical tools, key tasks, and workflows of the service.We will present the data bases structure and topics as well as their ArcGIS Online version. The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement n° 603839 (Project ASTARTE - Assessment, Strategy and Risk Reduction for

  16. The Use of Enzyme Hydrolysis to Assess the Seasonal Mobility and Bioavailability of Organic Phosphorus in Lake Sediments

    NASA Astrophysics Data System (ADS)

    Giles, C. D.; Lee, L. G.; Cade-Menun, B. J.; Rutila, B. C.; Schroth, A. W.; Xu, Y.; Hill, J. E.; Druschel, G.

    2013-12-01

    Lake sediments represent a significant internal source of phosphorus (P) in eutrophic freshwater systems during periods of high biological activity and oxygen depletion in sediments. Enzyme-labile and redox-sensitive P fractions may be a major component of the mobile sediment P pool which contributes to the development of harmful algal blooms. We present a high-through-put enzyme-based method for assessing potentially bioavailable (enzyme-labile) P in lake sediments and describe the relationship between enzyme-labile P, ascorbate-extractable (reactive) P and metals (Fe, Mn, Al, Ca), and P species identified using solution 31-P NMR spectroscopy. Sediment cores (0-10 cm) were collected from Lake Champlain over multiple years (Missisquoi Bay, VT, USA; 2007-2013). A principal components analysis of sediment properties suggests that enzyme-labile and reactive P, Mn, and Fe concentrations were more effective than the 31-P NMR methodology alone for differentiating algal bloom stage associated with periods of sediment anoxia. Bloom onset (July 2008) and peak bloom (August 2008, 2012) periods corresponded to the highest enzyme-labile P and lowest reactive P and metals proportions, despite 31-P NMR profiles which did not change significantly with respect to time and depth. High levels of reduced Fe and Mn ions were also detected in pore-water during this period, confirming previous reports that organic P bioavailability is linked to the redox status of sediments. High through-put analysis of enzyme-labile P fractions will provide spatially and temporally resolved information on bioavailable P pools at lower cost than traditional methods (i.e., 31-P NMR), and provide much-needed detail on aquatic P cycles during discrete stages of algal bloom development and sediment anoxia.

  17. On The Source Of The 25 November 1941 - Atlantic Tsunami

    NASA Astrophysics Data System (ADS)

    Baptista, M. A.; Lisboa, F. B.; Miranda, J. M. A.

    2015-12-01

    In this study we analyze the tsunami recorded in the North Atlantic following the 25 November 1941 earthquake. The earthquake with a magnitude of 8.3, located on the Gloria Fault, was one of the largest strike slip events recorded. The Gloria fault is a 500 km long scarp in the North Atlantic Ocean between 19W and 24W known to be a segment of the Eurasia-Nubia plate boundary between Iberia and the Azores. Ten tide stations recorded the tsunami. Six in Portugal (mainland, Azores and Madeira Islands), two in Morocco, one in the United Kingdom and one in Spain (Tenerife-Canary Islands). The tsunami waves reached Azores and Madeira Islands less than one hour after the main shock. The tide station of Casablanca (in Morocco) recorded the maximum amplitude of 0.54 m. All amplitudes recorded are lower than 0.5 m but the tsunami reached Portugal mainland in high tide conditions where the sea flooded some streets We analyze the 25 November 1941 tsunami data using the tide-records in the coasts of Portugal, Spain, Morocco and UK to infer its source. The use of wavelet analysis to characterize the frequency content of the tide-records shows predominant periods of 9-13min e 18-22min. A preliminary location of the tsunami source location was obtained Backward Ray Tracing (BRT). The results of the BRT technique are compatible with the epicenter location of the earthquake. We compute empirical Green functions for the earthquake generation area, and use a linear shallow water inversion technique to compute the initial water displacement. The comparison between forward modeling with observations shows a fair agreement with available data. This work received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement n° 603839 (Project ASTARTE - Assessment, Strategy and Risk Reduction for Tsunamis in Europe)"

  18. PRACE - The European HPC Infrastructure

    NASA Astrophysics Data System (ADS)

    Stadelmeyer, Peter

    2014-05-01

    The mission of PRACE (Partnership for Advanced Computing in Europe) is to enable high impact scientific discovery and engineering research and development across all disciplines to enhance European competitiveness for the benefit of society. PRACE seeks to realize this mission by offering world class computing and data management resources and services through a peer review process. This talk gives a general overview about PRACE and the PRACE research infrastructure (RI). PRACE is established as an international not-for-profit association and the PRACE RI is a pan-European supercomputing infrastructure which offers access to computing and data management resources at partner sites distributed throughout Europe. Besides a short summary about the organization, history, and activities of PRACE, it is explained how scientists and researchers from academia and industry from around the world can access PRACE systems and which education and training activities are offered by PRACE. The overview also contains a selection of PRACE contributions to societal challenges and ongoing activities. Examples of the latter are beside others petascaling, application benchmark suite, best practice guides for efficient use of key architectures, application enabling / scaling, new programming models, and industrial applications. The Partnership for Advanced Computing in Europe (PRACE) is an international non-profit association with its seat in Brussels. The PRACE Research Infrastructure provides a persistent world-class high performance computing service for scientists and researchers from academia and industry in Europe. The computer systems and their operations accessible through PRACE are provided by 4 PRACE members (BSC representing Spain, CINECA representing Italy, GCS representing Germany and GENCI representing France). The Implementation Phase of PRACE receives funding from the EU's Seventh Framework Programme (FP7/2007-2013) under grant agreements RI-261557, RI-283493 and RI

  19. Prostate cancer incidence and mortality in Portugal: trends, projections and regional differences.

    PubMed

    Pina, Francisco; Castro, Clara; Ferro, Ana; Bento, Maria J; Lunet, Nuno

    2016-08-01

    There is a large geographical variability in prostate cancer incidence and mortality trends, mostly because of heterogeneity in control efforts across regions. We aimed to describe the time trends in prostate cancer incidence and mortality in Portugal, overall and by region, and to estimate the number of incident cases and deaths in 2020. The number of cases and incidence rates in 1998-2009 were collected from the Regional Cancer Registries. The number of deaths and mortality rates were obtained from the WHO mortality database (1988-2003 and 2007-2013) and Statistics Portugal (2004-2006; 1991-2013 by region). JoinPoint analyses were used to identify significant changes in trends in age-standardized incidence and mortality rates. Incidence and mortality predictions for 2020 were performed using Poisson regression models and population projections provided by Statistics Portugal. In Portugal, prostate cancer incidence has been increasing since 1998 (1.8%/year), with the exception of the North Region, with a decrease since 2006 (-3.2%/year). An overall mortality decline has been observed since 1997 (-2.2%/year), although there were two patterns of mortality variation at the regional level: one with an inflection point or significant variation in the rates and the other without significant variation. If these trends are maintained, ∼8600 incident cases and 1700 deaths may be expected to occur in Portugal in 2020. Despite the overall increasing incidence and decreasing mortality, there is a large heterogeneity across regions. Future studies should address regional differences in the trends of prostate specific antigen screening and in the effective management of prostate cancer.

  20. Using a new incentive mechanism to improve wastewater sector performance: the case study of Italy.

    PubMed

    De Gisi, Sabino; Petta, Luigi; Farina, Roberto; De Feo, Giovanni

    2014-01-01

    The system of "Service Objectives", introduced by the Italian National Strategic Framework 2007-2013, is an innovative results-oriented programme concerning 4 thematic areas (education, care for the elderly and children, management of municipal solid wastes and integrated water service) in which the Ministry of Economic Development and eight Southern Italy districts are involved. The system was initially associated to an incentive mechanism which provided subsidies for a total amount of EUR 3 billion from the national Underdeveloped Areas Fund, according to the achievement of specific targets set for 11 service indicators in 2013. The indicators used for the integrated water service refer to the efficiency in water supply service as well as the coverage of wastewater treatment service. The aim of the study is to describe the activities carried out in Italy by the ENEA Agency in order to define a new performance indicator for wastewater treatment service taking into account the appropriateness and efficiency of existing plants equipment and, consequently, evaluating economic incentives. The proposed procedure takes into account both wastewater treatment demand and quality of wastewater treatment service offered to citizens. Input data, provided by the National Institute of Statistics (ISTAT), were elaborated in order to define appropriate parameters, with a multi-criteria analysis being used to define the new performance indicator. The applicability of the proposed procedure was verified considering all the 8 Southern Italy and Island districts (Abruzzo, Molise, Campania, Apulia, Basilicata, Calabria, Sicily and Sardinia) involved in the programme. The obtained results show that the quality of municipal wastewater may influence the calculation of the incentive amount. The performance indicators defined in this work might be conveniently extended to other contexts similar to the assessed geographical area (Southern Italy and Islands). Copyright © 2013 Elsevier Ltd

  1. Benchmarking on Tsunami Currents with ComMIT

    NASA Astrophysics Data System (ADS)

    Sharghi vand, N.; Kanoglu, U.

    2015-12-01

    There were no standards for the validation and verification of tsunami numerical models before 2004 Indian Ocean tsunami. Even, number of numerical models has been used for inundation mapping effort, evaluation of critical structures, etc. without validation and verification. After 2004, NOAA Center for Tsunami Research (NCTR) established standards for the validation and verification of tsunami numerical models (Synolakis et al. 2008 Pure Appl. Geophys. 165, 2197-2228), which will be used evaluation of critical structures such as nuclear power plants against tsunami attack. NCTR presented analytical, experimental and field benchmark problems aimed to estimate maximum runup and accepted widely by the community. Recently, benchmark problems were suggested by the US National Tsunami Hazard Mitigation Program Mapping & Modeling Benchmarking Workshop: Tsunami Currents on February 9-10, 2015 at Portland, Oregon, USA (http://nws.weather.gov/nthmp/index.html). These benchmark problems concentrated toward validation and verification of tsunami numerical models on tsunami currents. Three of the benchmark problems were: current measurement of the Japan 2011 tsunami in Hilo Harbor, Hawaii, USA and in Tauranga Harbor, New Zealand, and single long-period wave propagating onto a small-scale experimental model of the town of Seaside, Oregon, USA. These benchmark problems were implemented in the Community Modeling Interface for Tsunamis (ComMIT) (Titov et al. 2011 Pure Appl. Geophys. 168, 2121-2131), which is a user-friendly interface to the validated and verified Method of Splitting Tsunami (MOST) (Titov and Synolakis 1995 J. Waterw. Port Coastal Ocean Eng. 121, 308-316) model and is developed by NCTR. The modeling results are compared with the required benchmark data, providing good agreements and results are discussed. Acknowledgment: The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant

  2. Clinical and microbiological features of maternal sepsis: a retrospective study.

    PubMed

    Abir, G; Akdagli, S; Butwick, A; Carvalho, B

    2017-02-01

    Identifying pregnant women with sepsis is challenging because diagnostic clinical and laboratory criteria overlap with normal pregnant physiologic indices. Our primary study aim was to describe clinical and laboratory characteristics of women diagnosed with sepsis, severe sepsis and septic shock. Our secondary aim was to determine positive predictive values for International Classification of Disease (ICD)-9 billing codes for sepsis, severe sepsis, and septic shock. After gaining Institutional Review Board approval, we identified women with ICD-9 codes for sepsis, severe sepsis and septic shock who were admitted to a single tertiary obstetric center from 2007-2013. Diagnoses were confirmed using criteria from the International Sepsis Definitions Conference report. Demographic, obstetric, vital signs and laboratory data were abstracted by medical chart review. We identified 190 women with sepsis-related ICD-9 codes: of these, 35 (18%) women met the criteria for a clinical diagnosis of sepsis, severe sepsis or septic shock. Twenty (57%) women had a sepsis-related diagnosis after cesarean delivery. Twenty-one (60%) women had one or more pre-existing medical conditions and 19 (54%) women had one or more obstetric-related conditions. The genital tract was the most common site of infection. We observed considerable heterogeneity in maternal vital signs and laboratory indices for women with ICD-9 codes for sepsis, severe sepsis, and septic shock. The positive predictive value for each sepsis-related ICD-9 code was low: 16% (95% CI 10 to 24%) for sepsis, 10% (95% CI 3 to 25%) for severe sepsis and 24% (95% CI 10 to 46%) for septic shock. We identified marked heterogeneity in patient characteristics, clinical features, laboratory indices and microbiological findings among cohorts of women diagnosed with maternal sepsis, severe sepsis or septic shock. Based on our findings, the incidence of maternal sepsis using ICD-9 codes may be significantly overestimated. Copyright

  3. Nosocomial acquisition of methicillin-resistant Staphyloccocus aureus (MRSA) and extended-spectrum beta-lactamase (ESBL) Enterobacteriaceae in hospitalised patients: a prospective multicenter study

    PubMed Central

    2012-01-01

    Background The risk of acquisition of antibiotic resistant-bacteria during or shortly after antibiotic therapy is still unclear and it is often confounded by scarce data on antibiotic usage. Primary objective of the study is to compare rates of acquisition of methicillin-resistant Staphylococcus aureus and extended spectrum beta-lactamase-producing Enterobacteriaceae in hospitalised patients, after starting antibiotic therapy. Methods/Design The study, running in three European hospitals, is a multicenter, prospective, longitudinal, observational cohort study funded from the European Community's Seventh Framework Programme [FP7/2007-2013] within the project 'Impact of Specific Antibiotic Therapies on the prevalence of hUman host ResistaNt bacteria' (acronym SATURN). Nasal and rectal screening for methicillin-resistant Staphylococcus aureus and extended spectrum beta-lactamase-producing Enterobacteriaceae will be obtained at hospital admission, discharge, at antibiotic start (t0, within one hour) and at the following intervals: day 3 (t1), 7 (t2), 15 (t3), and 30 (t4). Two nested case-control studies will be performed. The objective of the first study will be to define individual level of risk related to specific antibiotics. Patients acquiring methicillin-resistant Staphylococcus aureus and extended spectrum beta-lactamase-producing Enterobacteriaceae (cases) will be compared with patients not acquiring antibiotic-resistant strains after starting antibiotic therapy (controls; ratio 1:4). To define the impact of antibiotics on new acquisition of target antibiotic-resistant bacteria, a second nested case-control study will be done (ratio 1:4). Control group will be selected among patients not receiving antibiotics, admitted in the same ward on the day of the corresponding case, with negative cultures at admission. Epidemiological, clinical and microbiological data will be prospective collected. Discussion The rationale of this study is to better understand the impact

  4. Detection of septic transfusion reactions to platelet transfusions by active and passive surveillance.

    PubMed

    Hong, Hong; Xiao, Wenbin; Lazarus, Hillard M; Good, Caryn E; Maitta, Robert W; Jacobs, Michael R

    2016-01-28

    Septic transfusion reactions (STRs) resulting from transfusion of bacterially contaminated platelets are a major hazard of platelet transfusion despite recent interventions. Active and passive surveillance for bacterially contaminated platelets was performed over 7 years (2007-2013) by culture of platelet aliquots at time of transfusion and review of reported transfusion reactions. All platelet units had been cultured 24 hours after collection and released as negative. Five sets of STR criteria were evaluated, including recent AABB criteria; sensitivity and specificity of these criteria, as well as detection by active and passive surveillance, were determined. Twenty of 51,440 platelet units transfused (0.004%; 389 per million) were bacterially contaminated by active surveillance and resulted in 5 STRs occurring 9 to 24 hours posttransfusion; none of these STRs had been reported by passive surveillance. STR occurred only in neutropenic patients transfused with high bacterial loads. A total of 284 transfusion reactions (0.55%) were reported by passive surveillance. None of these patients had received contaminated platelets. However, 6 to 93 (2.1%-32.7%) of these 284 reactions met 1 or more STR criteria, and sensitivity of STR criteria varied from 5.1% to 45.5%. These results document the continued occurrence of bacterial contamination of platelets resulting in STR in neutropenic patients, failure of passive surveillance to detect STR, and lack of specificity of STR criteria. These findings highlight the limitations of reported national STR data based on passive surveillance and the need to implement further measures to address this problem such as secondary testing or use of pathogen reduction technologies.

  5. Analysis of microseismic signals and temperature recordings for rock slope stability investigations in high mountain areas

    NASA Astrophysics Data System (ADS)

    Occhiena, C.; Coviello, V.; Arattano, M.; Chiarle, M.; Morra di Cella, U.; Pirulli, M.; Pogliotti, P.; Scavia, C.

    2012-07-01

    The permafrost degradation is a probable cause for the increase of rock instabilities and rock falls observed in recent years in high mountain areas, particularly in the Alpine region. The phenomenon causes the thaw of the ice filling rock discontinuities; the water deriving from it subsequently freezes again inducing stresses in the rock mass that may lead, in the long term, to rock falls. To investigate these processes, a monitoring system composed by geophones and thermometers was installed in 2007 at the Carrel hut (3829 m a.s.l., Matterhorn, NW Alps). In 2010, in the framework of the Interreg 2007-2013 Alcotra project no. 56 MASSA, the monitoring system has been empowered and renovated in order to meet project needs. In this paper, the data recorded by this renewed system between 6 October 2010 and 5 October 2011 are presented and 329 selected microseismic events are analysed. The data processing has concerned the classification of the recorded signals, the analysis of their distribution in time and the identification of the most important trace characteristics in time and frequency domain. The interpretation of the results has evidenced a possible correlation between the temperature trend and the event occurrence. The research is still in progress and the data recording and interpretation are planned for a longer period to better investigate the spatial-temporal distribution of microseismic activity in the rock mass, with specific attention to the relation of microseismic activity with temperatures. The overall goal is to verify the possibility to set up an effective monitoring system for investigating the stability of a rock mass under permafrost conditions, in order to supply the researchers with useful data to better understand the relationship between temperature and rock mass stability and, possibly, the technicians with a valid tool for decision-making.

  6. Interdisciplinary Environmental-health Science Throughout Disaster Lifecycles

    NASA Astrophysics Data System (ADS)

    Plumlee, G. S.; Morman, S. A.; Hoefen, T. M.

    2014-12-01

    Potential human health effects from exposures to hazardous disaster materials and environmental contamination are common concerns following disasters. Using several examples from US Geological Survey environmental disaster responses (e.g., 2001 World Trade Center, mine tailings spills, 2005 Hurricane Katrina, 2007-2013 wildfires, 2011 Gulf oil spill, 2012 Hurricane Sandy, 2013 Colorado floods) and disaster scenarios (2011 ARkStorm, 2013 SAFRR tsunami) this presentation will illustrate the role for collaborative earth, environmental, and health science throughout disaster lifecycles. Pre-disaster environmental baseline measurements are needed to help understand environmental influences on pre-disaster health baselines, and to constrain the magnitude of a disaster's impacts. During and following disasters, there is a need for interdisciplinary rapid-response and longer-term assessments that: sample and characterize the physical, chemical, and microbial makeup of complex materials generated by the disasters; fingerprint material sources; monitor, map, and model dispersal and evolution of disaster materials in the environment; help understand how the materials are modified by environmental processes; and, identify key characteristics and processes that influence the exposures and toxicity of disaster materials to humans and the living environment. This information helps emergency responders, public health experts, and cleanup managers: 1) identify short- and long-term exposures to disaster materials that may affect health; 2) prioritize areas for cleanup; and 3) develop appropriate disposal solutions or restoration uses for disaster materials. By integrating lessons learned from past disasters with geospatial information on vulnerable sources of natural or anthropogenic contaminants, the environmental health implications of looming disasters or disaster scenarios can be better anticipated, which helps enhance preparedness and resilience. Understanding economic costs of

  7. Tsunami Induced Sedimentation in Ports; A Case Study in Haydarpasa Harbor, Marmara Sea

    NASA Astrophysics Data System (ADS)

    Yalçıner, A. C.; Kian, R.; Velioglu, D.; Zaytsev, A.

    2015-12-01

    The movement of sea bottom or ground sediment material by tsunami cause erosion, deposition and hence bathymetry and topogrphy changes. The unexpected depth decrease at some parts of the enclosed basins and harbors may result in lack of movements of vessels. In order to understand the sediment movement inside the enclosed basins, Haydarpasa port in the sea of Marama is selected as a case study to understand the motion of tsunamis inside the port and identify their effects on harbor functions. The highest populated mega city Istanbul, located at north coast of the Sea of Marmara is one of the main centers of major economic activities in the region. In the study, the spatial and temporal changes of main tsunami parameters are investigated and their adverse effects on harbor performance are identified by analyzing the critical tsunami parameters (water elevation, current speed and momentum fluxes) in the port. Furthermore, the morphological changes due to tsunami induced flows are also considered. The morphological changes due to tsunamis can be governed by bathymetry and topography, tsunami current and the characteristics of ground material. Rouse number is one of the indicators to describe the initiation of sediment motion and transport modes under the flow. Therefore the morphological changes can be monitored by monitoring the change of the Rouse number. In this study the spatial and temporal change of Rouse number and hence modes of sediment transport in Haydarpasa port during a tsunami is investigated. Finally the functional loss of the port and the necessary strategies for reduction of tsunami impact and increase of resilience are also discussed. The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement No. 603839 (Project ASTARTE - Assessment, Strategy and Risk Reduction for Tsunamis in Europe)".

  8. Analysis of out-of-hospital cardiac arrest in Croatia – survival, bystander cardiopulmonary resuscitation, and impact of physician’s experience on cardiac arrest management: a single center observational study

    PubMed Central

    Lukić, Anita; Lulić, Ileana; Lulić, Dinka; Ognjanović, Zoran; Cerovečki, Davorin; Telebar, Siniša; Mašić, Ivica

    2016-01-01

    Aim To analyze the initial rhythm, bystander cardiopulmonary resuscitation (CPR) rate, and survival after out-of-hospital cardiac arrests (OHCA) in Varaždin County (Croatia), and to investigate whether physician’s inexperience in emergency medical services (EMS) has an impact on resuscitation management. Methods We reviewed clinical records and Revised Utstein cardiac arrest forms of all out-of-hospital resuscitations performed by EMS Varaždin (EMSVz), Croatia, from 2007-2013. To analyze the impact of physician’s inexperience in EMS (<1 year in EMS) on resuscitation management, we assessed physician’s turnover in EMSVz, as well as OHCA survival, airway management, and adherence to resuscitation guidelines in regard to physician’s EMS experience. Results Of 276 patients (median age 68 years, interquartile range [IQR] 16; 198 male; 37% ventricular fibrillation/ventricular tachycardia, bystander CPR rate 25%), 80 were transferred to hospital and 39 were discharged (median survival after discharge 23 months, IQR 46 months). During the 7-year study period, 29 newly graduated physicians inexperienced in EMS started to work in EMSVz (performing 77 resuscitations), while 48% of them stayed for less than one year. Airway management depended on physician’s EMS experience (P = 0.018): inexperienced physicians performed bag-valve-mask ventilation (BMV) more than the experienced, with no impact on survival rate. Physician’s EMS experience did not influence adherence to resuscitation guidelines (P = 0.668), survival to hospital discharge (P = 0.791), or survival time (P = 0.405). Conclusion OHCA survival rate of EMSVz resuscitations was higher than in Europe, but bystander CPR needs to be improved. Compared to experienced physicians, inexperienced physicians preferred BMV over intubation, but with similar adherence to resuscitation guidelines and survival after OHCA. PMID:28051284

  9. Plasma Free Hemoglobin Is an Independent Predictor of Mortality among Patients on Extracorporeal Membrane Oxygenation Support.

    PubMed

    Omar, Hesham R; Mirsaeidi, Mehdi; Socias, Stephanie; Sprenker, Collin; Caldeira, Christiano; Camporesi, Enrico M; Mangar, Devanand

    2015-01-01

    Hemolysis is common in all extracorporeal circuits as evident by the elevated plasma free hemoglobin (PFHb) level. We investigated whether increased hemolysis during extracorporeal membrane oxygenation (ECMO) is an independent mortality predictor. We performed a retrospective observational study of consecutive subjects who received ECMO at a tertiary care facility from 2007-2013 to investigate independent predictors of in-hospital mortality. We examined variables related to patient demographics, comorbidities, markers of hemolysis, ECMO characteristics, transfusion requirements, and complications. 24-hour PFHb > 50 mg/dL was used as a marker of severe hemolysis. 154 patients received ECMO for cardiac (n = 115) or pulmonary (n = 39) indications. Patients' mean age was 51 years and 75.3% were males. Compared to nonsurvivors, survivors had lower pre-ECMO lactic acid (p = 0.026), lower 24-hour lactic acid (p = 0.023), shorter ECMO duration (P = 0.01), fewer RBC transfusions on ECMO (p = 0.008) and lower level of PFHb 24-hours post ECMO implantation (p = 0.029). 24-hour PFHb > 50 mg/dL occurred in 3.9 % versus 15.5% of survivors and nonsurvivors, respectively, p = 0.002. A Cox proportional hazard analysis identified PFHb > 50 mg/dL 24-hours post ECMO as an independent predictor of mortality (OR= 3.4, 95% confidence interval: 1.3 - 8.8, p = 0.011). PFHb > 50 mg/dL checked 24-hour post ECMO implantation is a useful tool to predict mortality. We propose the routine checking of PFHb 24-hours after ECMO initiation for early identification and treatment of the cause of hemolysis.

  10. The tsunami effects of a volcanic island flank collapse on a semi-enclosed basin: The Pico-São Jorge channel in the Azores archipelago

    NASA Astrophysics Data System (ADS)

    Quartau, R.; Omira, R.; Ramalho, I.; Baptista, M. A.; Mitchell, N. C.

    2015-12-01

    The Azores archipelago is a set of nine volcanic islands in the middle of the North Atlantic, close to the triple junction between the North American, Eurasian and African plates. Due to their location, the islands are seismic and volcanically active, which makes them especially vulnerable to these types of hazards that could eventually trigger flank collapses, capable of generating destructive tsunamis. However, solid evidence of large-scale flank collapses has only been found recently in Pico Island (Costa et al., 2014; Quartau et al., 2015). This study investigates for the first time the tsunami effects of a flank collapse of the northeastern subaerial slope of Pico Island that occurred more than 70 ka ago. We first reconstructed the pre-event sub-aerial morphology of the island, and then numerically model the flank failure involving an estimated volume of ~8 km3, its flow toward and under the sea of ~14 km, and the subsequent tsunami generation and propagation. The modelling suggests that the collapse of Pico created a mega-tsunami that significantly impacted the coast of adjacent São Jorge Island only after 7 minutes after generation, with wave run-up reaching a maximum of 50 m at some coastlines. Most of the tsunami energy became trapped in the semi-enclosed basin between Pico and São Jorge Islands, with only relatively little energy escaping to neighboring islands. Acknowledgments The author wishes to acknowledge the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement n° 603839 (Project ASTARTE - Assessment, Strategy and Risk Reduction for Tsunamis in Europe)" for its major contribution for the success of this study. Publication supported by project FCT UID/GEO/50019/2013 - Instituto Dom Luiz. The author also acknowledges Fundação Luso-Americana para o Desenvolvimento for supporting the participation in the meeting.

  11. Capsid coding region diversity of re-emerging lineage C foot-and-mouth disease virus serotype Asia1 from India.

    PubMed

    Subramaniam, Saravanan; Mohapatra, Jajati K; Das, Biswajit; Sharma, Gaurav K; Biswal, Jitendra K; Mahajan, Sonalika; Misri, Jyoti; Dash, Bana B; Pattnaik, Bramhadev

    2015-07-01

    Foot-and-mouth disease virus (FMDV) serotype Asia1 was first reported in India in 1951, where three major genetic lineages (B, C and D) of this serotype have been described until now. In this study, the capsid protein coding region of serotype Asia1 viruses (n = 99) from India were analyzed, giving importance to the viruses circulating since 2007. All of the isolates (n = 50) recovered during 2007-2013 were found to group within the re-emerging cluster of lineage C (designated as sublineage C(R)). The evolutionary rate of sublineage C(R) was estimated to be slightly higher than that of the serotype as a whole, and the time of the most recent common ancestor for this cluster was estimated to be approximately 2001. In comparison to the older isolates of lineage C (1993-2001), the re-emerging viruses showed variation at eight amino acid positions, including substitutions at the antigenically critical residues VP279 and VP2131. However, no direct correlation was found between sequence variations and antigenic relationships. The number of codons under positive selection and the nature of the selection pressure varied widely among the structural proteins, implying a heterogeneous pattern of evolution in serotype Asia1. While episodic diversifying selection appears to play a major role in shaping the evolution of VP1 and VP3, selection pressure acting on codons of VP2 is largely pervasive. Further, episodic positive selection appears to be responsible for the early diversification of lineage C. Recombination events identified in the structural protein coding region indicates its probable role in adaptive evolution of serotype Asia1 viruses.

  12. The recurrent campylobacteriosis epidemic over Christmas and New Year in European countries, 2006-2014.

    PubMed

    Bless, Philipp Justus; Schmutz, Claudia; Mäusezahl, Daniel

    2017-07-11

    Campylobacteriosis is the most frequently reported foodborne disease in Europe with a notification rate of 71 per 100,000 population in the European Union in 2014. Surveillance data show a clear seasonality whereby case numbers peak during summer months in entire Europe and at the turn of the year, especially in Germany and Switzerland. A detailed description of European surveillance data by country at the turn of the year was missing so far. The objectives of the presented work were to describe national surveillance data of The European Surveillance System for 14 countries during winter times and to generate hypotheses for the observed seasonality of campylobacteriosis cases. The analysis included 317,986 cases notified between calendar weeks 45 and 8 of winter seasons 2006/2007-2013/2014. Winter peaks in weekly case notifications and notification rates were observed for Austria, Belgium, Finland, Germany, Luxembourg, The Netherlands, Switzerland and Sweden while for Denmark, France, Ireland, Italy, Norway and the United Kingdom no unusual increase was observed. Generally, weekly notification rates peaked in calendar week 1 or 2 after a strong decline in the last week of December and reached values of a multiple of the observed notification rates in the weeks before or after the peak e.g. up to 6.5 notifications per 100,000 population per week in Luxembourg. Disease onset of cases notified during winter peaks occurred predominantly in calendar weeks 52 and 1 and point towards risk exposures around Christmas and New Year. The consumption of meat fondue or table top grilling poses such a risk and is popular in many countries with an observed winter peak. Additionally, increased travel activities over the festive season could foster campylobacteriosis transmission. Surveillance artefacts (e.g. reporting delays due to public holidays) should be excluded as causes for country-specific winter peaks before investigating risk exposures.

  13. Health conditions in rural areas with high livestock density: Analysis of seven consecutive years.

    PubMed

    van Dijk, Christel E; Zock, Jan-Paul; Baliatsas, Christos; Smit, Lidwien A M; Borlée, Floor; Spreeuwenberg, Peter; Heederik, Dick; Yzermans, C Joris

    2017-03-01

    Previous studies investigating health conditions of individuals living near livestock farms generally assessed short time windows. We aimed to take time-specific differences into account and to compare the prevalence of various health conditions over seven consecutive years. The sample consisted of 156,690 individuals registered in 33 general practices in a (rural) area with a high livestock density and 101,015 patients from 23 practices in other (control) areas in the Netherlands. Prevalence of health conditions were assessed using 2007-2013 electronic health record (EHR) data. Two methods were employed to assess exposure: 1) Comparisons between the study and control areas in relation to health problems, 2) Use of individual estimates of livestock exposure (in the study area) based on Geographic Information System (GIS) data. A higher prevalence of chronic bronchitis/bronchiectasis, lower respiratory tract infections and vertiginous syndrome and lower prevalence of respiratory symptoms and emphysema/COPD was found in the study area compared with the control area. A shorter distance to the nearest farm was associated with a lower prevalence of upper respiratory tract infections, respiratory symptoms, asthma, COPD/emphysema, allergic rhinitis, depression, eczema, vertiginous syndrome, dizziness and gastrointestinal infections. Especially exposure to cattle was associated with less health conditions. Living within 500m of mink farms was associated with increased chronic enteritis/ulcerative colitis. Livestock-related exposures did not seem to be an environmental risk factor for the occurrence of health conditions. Nevertheless, lower respiratory tract infections, chronic bronchitis and vertiginous syndrome were more common in the area with a high livestock density. The association between exposure to minks and chronic enteritis/ulcerative colitis remains to be elucidated.

  14. Multiple introductions of a reassortant H5N1 avian influenza virus of clade 2.3.2.1c with PB2 gene of H9N2 subtype into Indian poultry.

    PubMed

    Tosh, Chakradhar; Nagarajan, Shanmugasundaram; Kumar, Manoj; Murugkar, Harshad V; Venkatesh, Govindarajulu; Shukla, Shweta; Mishra, Amit; Mishra, Pranav; Agarwal, Sonam; Singh, Bharati; Dubey, Prashant; Tripathi, Sushil; Kulkarni, Diwakar D

    2016-09-01

    Highly pathogenic avian influenza (HPAI) H5N1 viruses are a threat to poultry in Asia, Europe, Africa and North America. Here, we report isolation and characterization of H5N1 viruses isolated from ducks and turkeys in Kerala, Chandigarh and Uttar Pradesh, India between November 2014 and March 2015. Genetic and phylogenetic analyses of haemagglutinin gene identified that the virus belonged to a new clade 2.3.2.1c which has not been detected earlier in Indian poultry. The virus possessed molecular signature for high pathogenicity to chickens, which was corroborated by intravenous pathogenicity index of 2.96. The virus was a reassortant which derives its PB2 gene from H9N2 virus isolated in China during 2007-2013. However, the neuraminidase and internal genes are of H5N1 subtype. Phylogenetic and network analysis revealed that after detection in China in 2013/2014, the virus moved to Europe, West Africa and other Asian countries including India. The analyses further indicated multiple introductions of H5N1 virus in Indian poultry and internal spread in Kerala. One of the outbreaks in ducks in Kerala is linked to the H5N1 virus isolated from wild birds in Dubai suggesting movement of virus probably through migration of wild birds. However, the outbreaks in ducks in Chandigarh and Uttar Pradesh were from an unknown source in Asia which also contributed gene pools to the outbreaks in Europe and West Africa. The widespread incidence of the novel H5N1 HPAI is similar to the spread of clade 2.2 ("Qinghai-like") virus in 2005, and should be monitored to avoid threat to animal and public health.

  15. A zonation technique for landslide susceptibility in southern Taiwan

    NASA Astrophysics Data System (ADS)

    Chiang, Jie-Lun; Tian, Yu-Qing; Chen, Yie-Ruey; Tsai, Kuang-Jung

    2016-04-01

    In recent years, global climate changes violently, extreme rainfall events occur frequently and also cause massive sediment related disasters in Taiwan. The disaster seriously hit the regional economic development and national infrastructures. For example, in August, 2009, the typhoon Morakot brought massive rainfall especially in the mountains in Chiayi County and Kaohsiung County in which the cumulative maximum rainfall was up to 2900 mm; meanwhile, the cumulative maximum rainfall was over 1500m.m. in Nantou County, Tainan County and Pingtung County. The typhoon caused severe damage in southern Taiwan. The study will search for the influence on the sediment hazards caused by the extreme rainfall and hydrological environmental changes focusing on southern Taiwan (including Chiayi, Tainan, Kaohsiung and Pingtung). The instability index and kriging theories are applied to analyze the factors of landslide to determine the susceptibility in southern Taiwan. We collected the landslide records during the period year, 2007~2013 and analyzed the instability factors including elevation, slope, aspect, soil, and geology. Among these factors, slope got the highest weight. The steeper the slope is, the more the landslides occur. As for the factor of aspect, the highest probability falls on the Southwest. However, this factor has the lowest weight among all the factors. Likewise, Darkish colluvial soil holds the highest probability of collapses among all the soils. Miocene middle Ruifang group and its equivalents have the highest probability of collapses among all the geologies. In this study, Kriging was used to establish the susceptibility map in southern Taiwan. The instability index above 4.21 can correspond to those landslide records. The potential landslide area in southern Taiwan, where collapses more likely occur, belongs to high level and medium-high level; the area is 5.12% and 17.81% respectively.

  16. Oral appliance treatment in moderate and severe obstructive sleep apnoea patients non-adherent to CPAP.

    PubMed

    Gjerde, K; Lehmann, S; Berge, M E; Johansson, A-K; Johansson, A

    2016-04-01

    The aim of this retrospective study was to evaluate the effect of individually adjusted custom-made mandibular advancement device/oral appliance (OA) in treatment of patients with moderate and severe obstructive sleep apnoea (OSA), who were non-adherent to continuous positive airway pressure (CPAP) therapy. During 2007-2013, 116 patients with moderate (n = 82) and severe (n = 34) OSA non-adherent to CPAP treatment were referred for dental management with an individually adjusted OA at a specialist sleep clinic. Ten of the participants (8·6%) were lost to follow-up, leaving the data set to consist of 106 patients (71 men/35 women, mean age 57 year, range 28-90). Nocturnal respiratory polygraphic recordings were performed at baseline and follow-up. Average time between baseline polygraphy and follow-up was 12 months. A successful OA treatment outcome was based on polygraphy at the follow-up and divided into three groups: 1 = AHI <5; 2 = 5 ≤ AHI <10 and >50% reduction in baseline AHI; and 3. >50% reduction in baseline AHI. If there was a ≤ 50% reduction in baseline AHI at the follow-up, the treatment was considered as a failure. The overall treatment success rate was 75%. There was no significant difference in success rates between patients in the moderate and severe categories (69% and 77%, respectively). Low oxygen saturation (SpO2 nadir) had a high predictive value for OA treatment failure. OA treatment of patients non-adherent to CPAP is efficient and especially promising for the severe OSA group who are at greatest risks for developing serious comorbidities, if left untreated. © 2015 The Authors. Journal of Oral Rehabilitation Published by John Wiley & Sons Ltd.

  17. SALVEREMO, an automatic system for the search and rescue in the wilderness and mountain areas

    NASA Astrophysics Data System (ADS)

    Penna, Roberto; Allasia, Walter; Bianchi, Luca; Licata, Enrico; Duranti, Pierluigi; Molino, Andrea; Bagalini, Enea; Sagliocco, Sergio; Scarafia, Simone; Prinetto, Paolo; Airofarulla, Giuseppe; Carelli, Alberto

    2016-04-01

    SALVEREMO project aims at designing and prototyping an innovative system for searching and rescuing individuals (especially hikers and mountaineers) who got lost or in peril in wilderness or mountain areas. It makes use of Remotely Piloted Aircraft System (RPAS) equipped with a sensor suite specifically selected according to the requirements identified involving alpine rescuers and government officials. The peculiarity of the proposed solution is the exploitation and integration of the special skill and expertise coming from different competence fields. It will dramatically decrease the searching time in the wilderness and remote areas off the beaten tracks, providing rescuers and operators with a decision support system increasing successful results and reducing rescue missions costs. The system benefits from the adoption of a scaled-down Base Transceiver Station (BTS) embarked in the payload sensor suite of a small RPAS that can be carried in a back pack of rescuers. A Software Defined Radio (SDR) board implementing the BTS protocol stack has been integrated in a complex sensor suite made up of open processing boards and camera devices. Moreover computer vision (CV) algorithms for real time pattern detection and image enhancements have been investigated for assisting the rescuers during the searching operations. An easy-to-use ground station application has been developed for speeding up the overall mission accomplishment. Aknowledgement SALVEREMO project is a research project co-funded by Regione Piemonte according to the call for proposal POR F.E.S.R. 2007/2013, "Linea di attività I.1.3-Innovazione e PMI - Polo della Meccatronica e dei Sistemi Avanzati di Produzione". The authors want to thank "Il Soccorso Alpino Italiano" for the invaluable support for establishing operative requirements.

  18. TU-G-210-00: Treatment Planning Strategies, Modeling, Control

    SciTech Connect

    2015-06-15

    Modeling can play a vital role in predicting, optimizing and analyzing the results of therapeutic ultrasound treatments. Simulating the propagating acoustic beam in various targeted regions of the body allows for the prediction of the resulting power deposition and temperature profiles. In this session we will apply various modeling approaches to breast, abdominal organ and brain treatments. Of particular interest is the effectiveness of procedures for correcting for phase aberrations caused by intervening irregular tissues, such as the skull in transcranial applications or inhomogeneous breast tissues. Also described are methods to compensate for motion in targeted abdominal organs such as the liver or kidney. Douglas Christensen – Modeling for Breast and Brain HIFU Treatment Planning Tobias Preusser – TRANS-FUSIMO – An Integrative Approach to Model-Based Treatment Planning of Liver FUS Tobias Preusser – TRANS-FUSIMO – An Integrative Approach to Model-Based Treatment Planning of Liver FUS Learning Objectives: Understand the role of acoustic beam modeling for predicting the effectiveness of therapeutic ultrasound treatments. Apply acoustic modeling to specific breast, liver, kidney and transcranial anatomies. Determine how to obtain appropriate acoustic modeling parameters from clinical images. Understand the separate role of absorption and scattering in energy delivery to tissues. See how organ motion can be compensated for in ultrasound therapies. Compare simulated data with clinical temperature measurements in transcranial applications. Supported by NIH R01 HL172787 and R01 EB013433 (DC); EU Seventh Framework Programme (FP7/2007-2013) under 270186 (FUSIMO) and 611889 (TRANS-FUSIMO)(TP); and P01 CA159992, GE, FUSF and InSightec (UV)

  19. TU-G-210-02: TRANS-FUSIMO - An Integrative Approach to Model-Based Treatment Planning of Liver FUS

    SciTech Connect

    Preusser, T.

    2015-06-15

    Modeling can play a vital role in predicting, optimizing and analyzing the results of therapeutic ultrasound treatments. Simulating the propagating acoustic beam in various targeted regions of the body allows for the prediction of the resulting power deposition and temperature profiles. In this session we will apply various modeling approaches to breast, abdominal organ and brain treatments. Of particular interest is the effectiveness of procedures for correcting for phase aberrations caused by intervening irregular tissues, such as the skull in transcranial applications or inhomogeneous breast tissues. Also described are methods to compensate for motion in targeted abdominal organs such as the liver or kidney. Douglas Christensen – Modeling for Breast and Brain HIFU Treatment Planning Tobias Preusser – TRANS-FUSIMO – An Integrative Approach to Model-Based Treatment Planning of Liver FUS Tobias Preusser – TRANS-FUSIMO – An Integrative Approach to Model-Based Treatment Planning of Liver FUS Learning Objectives: Understand the role of acoustic beam modeling for predicting the effectiveness of therapeutic ultrasound treatments. Apply acoustic modeling to specific breast, liver, kidney and transcranial anatomies. Determine how to obtain appropriate acoustic modeling parameters from clinical images. Understand the separate role of absorption and scattering in energy delivery to tissues. See how organ motion can be compensated for in ultrasound therapies. Compare simulated data with clinical temperature measurements in transcranial applications. Supported by NIH R01 HL172787 and R01 EB013433 (DC); EU Seventh Framework Programme (FP7/2007-2013) under 270186 (FUSIMO) and 611889 (TRANS-FUSIMO)(TP); and P01 CA159992, GE, FUSF and InSightec (UV)

  20. TU-G-210-03: Acoustic Simulations in Transcranial MRgFUS: Treatment Prediction and Analysis

    SciTech Connect

    Vyas, U.

    2015-06-15

    Modeling can play a vital role in predicting, optimizing and analyzing the results of therapeutic ultrasound treatments. Simulating the propagating acoustic beam in various targeted regions of the body allows for the prediction of the resulting power deposition and temperature profiles. In this session we will apply various modeling approaches to breast, abdominal organ and brain treatments. Of particular interest is the effectiveness of procedures for correcting for phase aberrations caused by intervening irregular tissues, such as the skull in transcranial applications or inhomogeneous breast tissues. Also described are methods to compensate for motion in targeted abdominal organs such as the liver or kidney. Douglas Christensen – Modeling for Breast and Brain HIFU Treatment Planning Tobias Preusser – TRANS-FUSIMO - An Integrative Approach to Model-Based Treatment Planning of Liver FUS Urvi Vyas – Acoustic Simulations in Transcranial MRgFUS: Treatment Prediction and Analysis Learning Objectives: Understand the role of acoustic beam modeling for predicting the effectiveness of therapeutic ultrasound treatments. Apply acoustic modeling to specific breast, liver, kidney and transcranial anatomies. Determine how to obtain appropriate acoustic modeling parameters from clinical images. Understand the separate role of absorption and scattering in energy delivery to tissues. See how organ motion can be compensated for in ultrasound therapies. Compare simulated data with clinical temperature measurements in transcranial applications. Supported by NIH R01 HL172787 and R01 EB013433 (DC); EU Seventh Framework Programme (FP7/2007-2013) under 270186 (FUSIMO) and 611889 (TRANS-FUSIMO)(TP); and P01 CA159992, GE, FUSF and InSightec (UV)

  1. TU-G-210-01: Modeling for Breast and Brain HIFU Treatment Planning

    SciTech Connect

    Christensen, D.

    2015-06-15

    Modeling can play a vital role in predicting, optimizing and analyzing the results of therapeutic ultrasound treatments. Simulating the propagating acoustic beam in various targeted regions of the body allows for the prediction of the resulting power deposition and temperature profiles. In this session we will apply various modeling approaches to breast, abdominal organ and brain treatments. Of particular interest is the effectiveness of procedures for correcting for phase aberrations caused by intervening irregular tissues, such as the skull in transcranial applications or inhomogeneous breast tissues. Also described are methods to compensate for motion in targeted abdominal organs such as the liver or kidney. Douglas Christensen – Modeling for Breast and Brain HIFU Treatment Planning Tobias Preusser – TRANS-FUSIMO – An Integrative Approach to Model-Based Treatment Planning of Liver FUS Tobias Preusser – TRANS-FUSIMO – An Integrative Approach to Model-Based Treatment Planning of Liver FUS Learning Objectives: Understand the role of acoustic beam modeling for predicting the effectiveness of therapeutic ultrasound treatments. Apply acoustic modeling to specific breast, liver, kidney and transcranial anatomies. Determine how to obtain appropriate acoustic modeling parameters from clinical images. Understand the separate role of absorption and scattering in energy delivery to tissues. See how organ motion can be compensated for in ultrasound therapies. Compare simulated data with clinical temperature measurements in transcranial applications. Supported by NIH R01 HL172787 and R01 EB013433 (DC); EU Seventh Framework Programme (FP7/2007-2013) under 270186 (FUSIMO) and 611889 (TRANS-FUSIMO)(TP); and P01 CA159992, GE, FUSF and InSightec (UV)

  2. MExLab Planetary Geoportal: 3D-access to planetary images and results of spatial data analysis

    NASA Astrophysics Data System (ADS)

    Karachevtseva, I.; Garov, A.

    2015-10-01

    MExLab Planetary Geoportal was developed as Geodesy and Cartography Node which provide access to results of study of celestial bodies such as DEM and orthoimages, as well as basemaps, crater catalogues and derivative products: slope, roughness, crater density (http://cartsrv.mexlab.ru/geoportal). The main feature of designed Geoportal is the ability of spatial queries and access to the contents selecting from the list of available data set (Phobos, Mercury, Moon, including Lunokhod's archive data). Prior version of Geoportal has been developed using Flash technology. Now we are developing new version which will use 3D-API (OpenGL, WebGL) based on shaders not only for standard 3D-functionality, but for 2D-mapping as well. Users can obtain quantitative and qualitative characteristics of the objects in graphical, tabular and 3D-forms. It will bring the advantages of unification of code and speed of processing and provide a number of functional advantages based on GIS-tools such as: - possibility of dynamic raster transform for needed map projection; - effective implementation of the co-registration of planetary images by combining spatial data geometries; - presentation in 3D-form different types of data, including planetary atmospheric measurements, subsurface radar data, ect. The system will be created with a new software architecture, which has a potential for development and flexibility in reconfiguration based on cross platform solution: - an application for the three types of platforms: desktop (Windows, Linux, OSX), web platform (any HTML5 browser), and mobile application (Android, iOS); - a single codebase shared between platforms (using cross compilation for Web); - a new telecommunication solution to connect between modules and external system like PROVIDE WebGIS (http://www.provide-space.eu/progis/). The research leading to these result was partly supported by the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement n

  3. Peritoneal Metastases from Gastroenteropancreatic Neuroendocrine Tumors: Incidence, Risk Factors and Prognosis.

    PubMed

    Madani, Ariana; Thomassen, Irene; van Gestel, Yvette R B M; van der Bilt, Jarmila D W; Haak, Harm R; de Hingh, Ignace H J T; Lemmens, Valery E P P

    2017-08-01

    Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are rare neoplasms and data on peritoneal metastases (PM) from these tumors are scarce. The aim of this study was to present population-based data on the incidence, risk factors, and survival of synchronous PM in GEP-NETs. Data from all patients diagnosed with a GEP-NET during 2007-2013 were collected from the Netherlands Cancer Registry. Age-standardized incidence rates were calculated and risk factors for developing PM were determined using multivariable logistic regression analysis. Survival was investigated using Kaplan-Meier and Cox regression analyses. A total of 4114 patients were diagnosed with a GEP-NET. PM were diagnosed in 234 patients (19% of patients with metastasized disease, representing 6% of all GEP-NETs). The incidence of patients diagnosed with PM was 1.6:1,000,000 persons per year. Risk factors for developing PM were higher age (odds ratio [OR] 1.4, 95% CI 1.0-2.0) and primary tumor location in the small intestine (OR 3.5, 95% CI 2.1-5.7) or colon (OR 2.5, 95% CI 1.4-4.4). Small intestinal NETs with PM had the best survival, while appendiceal NETs with PM had the poorest survival (5-year survival rates of 67 and 7%, respectively). Multivariate analysis showed that survival in patients with PM was worse compared with patients without metastases; however, the presence of PM among all metastasized patients was not associated with worse survival. This nationwide population-based study provides relevant insight into the incidence and risk factors of PM in GEP-NETs, and reveals detailed site-specific data on the presence of PM and survival data that may contribute to develop individualized treatment strategies in patients with these heterogeneous neoplasms.

  4. Primary stenting is not necessary in benign central venous stenosis.

    PubMed

    Rangel, Lynsey E; Lyden, Sean P; Clair, Daniel G

    2017-08-11

    To evaluate central venous stenosis (CVS) etiologies and presentation within a vascular surgery practice. We evaluated endovascular treatment modalities and the patency rates of our interventions. 5 year retrospective review of endovascular intervention for CVS. Patient demographics, medical comorbidities, and variables were collected including etiology, indwelling device, previous upper extremity (UE) deep venous thrombosis (DVT), long term UE indwelling device (defined as greater than 30 days), malignancy status, hypercoagulable disorders, history of radiation or mediastinal fibrosis or masses, and anticoagulation and/or antiplatelet therapy. Follow-up variables included symptoms, imaging, and anticoagulation and/or antiplatelet utilization. Living patients without recent follow up were contacted with a telephone survey regarding current symptoms. Patency was evaluated by imaging or clinically by recurrence of signs or symptoms through January 2016. A total of 61 patients underwent attempted endovascular CVS interventions from January 2007-2013. 47 (83%) patients had successful interventions. There were 22 (36%) end-stage renal disease (ESRD) patients. The primary etiology in 79% of patients was benign CVS secondary to an indwelling device. 89% of the interventions were primary angioplasty (PTA). The overall primary patency rates at 6, 12, and 24 months were 49%, 34%, and 24% respectively. Secondary patency rates at 6, 12, and 24 months were 97%, 93%, and 88% respectively. There were no statistical differences in demographics or outcomes in patients treated successfully with PTA or those requiring stenting. There was no statistical difference in the patency rates between ESRD and non-ESRD patients. Previous interventions were not a predictor of loss of patency. Our study supported the rising trend of benign CVS predominantly secondary to indwelling devices. We demonstrated acceptable secondary patency with PTA alone. This study adds further supports for a primary

  5. Assessment of Malawi's success in child mortality reduction through the lens of the Catalytic Initiative Integrated Health Systems Strengthening programme: Retrospective evaluation.

    PubMed

    Doherty, Tanya; Zembe, Wanga; Ngandu, Nobubelo; Kinney, Mary; Manda, Samuel; Besada, Donela; Jackson, Debra; Daniels, Karen; Rohde, Sarah; van Damme, Wim; Kerber, Kate; Daviaud, Emmanuelle; Rudan, Igor; Muniz, Maria; Oliphant, Nicholas P; Zamasiya, Texas; Rohde, Jon; Sanders, David

    2015-12-01

    Malawi is estimated to have achieved its Millennium Development Goal (MDG) 4 target. This paper explores factors influencing progress in child survival in Malawi including coverage of interventions and the role of key national policies. We performed a retrospective evaluation of the Catalytic Initiative (CI) programme of support (2007-2013). We developed estimates of child mortality using four population household surveys undertaken between 2000 and 2010. We recalculated coverage indicators for high impact child health interventions and documented child health programmes and policies. The Lives Saved Tool (LiST) was used to estimate child lives saved in 2013. The mortality rate in children under 5 years decreased rapidly in the 10 CI districts from 219 deaths per 1000 live births (95% confidence interval (CI) 189 to 249) in the period 1991-1995 to 119 deaths (95% CI 105 to 132) in the period 2006-2010. Coverage for all indicators except vitamin A supplementation increased in the 10 CI districts across the time period 2000 to 2013. The LiST analysis estimates that there were 10 800 child deaths averted in the 10 CI districts in 2013, primarily attributable to the introduction of the pneumococcal vaccine (24%) and increased household coverage of insecticide-treated bednets (19%). These improvements have taken place within a context of investment in child health policies and scale up of integrated community case management of childhood illnesses. Malawi provides a strong example for countries in sub-Saharan Africa of how high impact child health interventions implemented within a decentralised health system with an established community-based delivery platform, can lead to significant reductions in child mortality.

  6. Demographic and socioeconomic inequalities for self-rated health and happiness in elderly: the situation for Turkey regarding World Values Survey between 1990 and 2013.

    PubMed

    Ergin, Isil; Mandiracioglu, Aliye

    2015-01-01

    To define the socioeconomic and demographic determinants for self-rated health and happiness for Turkish elderly (≥60) using the World Values Survey (WVS) database. WVS data for Turkey covering 23 years (1990-2013) with five separate cross-sections (1990, 1996, 2001, 2007, 2013) were pooled for analysis (n=870). Dependent variables were self-rated health (SRH) and perception of happiness.Their relation with age, sex, number of children, marital status, income, education, employment status and class perception were evaluated. Chi-square and logistic regression analysis were used. Regression coefficients and their standard errors were derived to calculate odds ratios. Mean age was 66.96±5.78 (60-91), 58.16% were male and 76.32% were married. The majority (61.10%) was at lowest income level and 80.60% had education attainment at primary level or below. Very happy/quite happy were 81.77% while only 46.59% perceived their health as very good/good. The crisis year (2001) increased the risk of bad self-rated health 4.4 times, being a women 2.0 times, while being a widow had a 2.3-fold, low-income 3.0-fold effect. The odds for unhappy status was increased 4.3 times at low-income levels and 8.4 times for the divorced/separate living partners. Happiness state improved after crisis period. SRH and happiness of Turkish elderly bare demographic and socioeconomic inequalities. The inexistence of a partner, being a women, low-income level and major threats for it, like economic crisis, are important drivers for elderly health and happiness. To improve well-being of elderly, better social policies for income is essential and at economic crisis times, support policies should be prioritized for vulnerable groups, including elderly. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  7. Aerosol classification using EARLINET measurements for an intensive observational period

    NASA Astrophysics Data System (ADS)

    Papagiannopoulos, Nikolaos; Mona, Lucia; Pappalardo, Gelsomina

    2016-04-01

    ACTRIS (Aerosols, Clouds and Trace gases Research Infrastructure Network) organized an intensive observation period during summer 2012. This campaign aimed at the provision of advanced observations of physical and chemical aerosol properties, at the delivery of information about the 3D distribution of European atmospheric aerosols, and at the monitoring of Saharan dust intrusions events. EARLINET (European Aerosol Research Lidar Network) participated in the ACTRIS campaign through the addition of measurements according to the EARLINET schedule as well as daily lidar-profiling measurements around sunset by 11 selected lidar stations for the period from 8 June - 17 July. EARLINET observations during this almost two-month period are used to characterize the optical properties and vertical distribution of long-range transported aerosol over the broader area of Mediterranean basin. The lidar measurements of aerosol intensive parameters (lidar ratio, depolarization, Angstrom exponents) are shown to vary with location and aerosol type. A methodology based on EARLINET observations of frequently observed aerosol types is used to classify aerosols into seven separate types. The summertime Mediterranean basin is prone to African dust aerosols. Two major dust events were studied. The first episode occurred from the 18 to 21 of the June and the second one lasted from 28 June to 6 July. The lidar ratio within the dust layer was found to be wavelength independent with mean values of 58±14 sr at 355 nm and 57±11 sr at 532 nm. For the particle linear depolarization ratio, mean values of 0.27±0.04 at 532 nm have been found. Acknowledgements. The financial support for EARLINET in the ACTRIS Research Infrastructure Project by the European Union's Horizon 2020 research and innovation programme under grant agreement no. 654169 and previously under grant agreement no. 262254 in the Seventh Framework Programme (FP7/2007-2013) is gratefully acknowledged.

  8. Turbulent Dynamo Amplification of Magnetic Fields in Laser-Produced Plasmas

    NASA Astrophysics Data System (ADS)

    Tzeferacos, Petros

    2016-10-01

    Magnetic fields are ubiquitous in the Universe, as revealed by diffuse radio-synchrotron emission and Faraday rotation observations, with strengths from a few nG to tens of μG. The energy density of these fields is typically comparable to the energy density of the fluid motions of the plasma in which they are embedded, making magnetic fields essential players in the dynamics of the luminous matter in the Universe. The standard model for the origin of these intergalactic magnetic fields is through the amplification of seed fields via turbulent dynamo to the level consistent with current observations. We have conceived and conducted a series of experiments using high-power laser facilities to study the amplification of magnetic fields via turbulence. In these experiments, we characterize the properties of the fluid and the magnetic field turbulence using a comprehensive suite of plasma and magnetic field diagnostics. We describe the large-scale 3D simulations we performed with the radiation-MHD code FLASH on ANL's Mira to help design and interpret the experiments. We then discuss the results of the experiments, which indicate magnetic Reynolds numbers above the expected dynamo threshold are achieved and seed magnetic fields produced by the Biermann battery mechanism are amplified by turbulent dynamo. We relate our findings to processes occurring in galaxy clusters. We acknowledge funding and resources from the ERC (FP7/2007-2013, no. 256973 and 247039), and the U.S. DOE, Contract No. B591485 to LLNL, FWP 57789 to ANL, Grant No. DE-NA0002724 to the University of Chicago, and contract DE-AC02-06CH11357 to ALCF at ANL.

  9. Constraining the Geological Time Scale for the Upper Cretaceous in the Edmonton Group: Western Canadian Sedimentary Basin

    NASA Astrophysics Data System (ADS)

    Heredia, B.; Gaylor, J. R.; Hilgen, F.; Kuiper, K.; Mezger, K.; Wijbrans, J. R.; Quidelleur, X.; Huesing, S.

    2011-12-01

    The Cretaceous period records evidence of sea-level changes, remarkably cyclic sedimentation, major perturbations in carbon cycles during anoxic events, and large scale igneous activity. Astronomically-tuned time scales are only partially consistent with recalculated Ar-Ar constraints for the Cretaceous-Paleogene (K-Pg) boundary, but differ in number and tuning of 405-kyr eccentricity related cycles. The exposures of Upper Cretaceous strata along the Red Deer River (Western Canadian Sedimentary Basin) offer a unique opportunity to examine aspects of marine, tectonic, and climatic influenced sediments. The uppermost part of the Knudsen Farm section is a well-preserved continuous section, mainly composed by climatically controlled alternations of silt and organic rich horizons, in which altered volcanic ash layers have been deposited. In this section, the K-Pg boundary has been placed at the base of a prominent coal layer (Nevis coal), approx. 24 m from the base of the c29r. We present a compilation of paleomagnetic data, chemical, colour and magnetic susceptibility proxies, and Ar-Ar, K-Ar and U-Pb (CA-TIMS) for the uppermost part of the Maastrichtian, including the base of the c29r to the K-Pg boundary and up to the lowermost Danian. High-resolution radioisotopic ages and the multi-proxy lithological and geochemical datasets are used to develop a cyclostratigraphic reconstruction of this interval, thus permitting the synchronisation of rock clocks close to the K-Pg boundary. This research is funded by the European Community's Seventh Framework Program (FP7/2007-2013) under grant agreement no [215458].

  10. Reproductive Ratio for the Local Spread of African Swine Fever in Wild Boars in the Russian Federation.

    PubMed

    Iglesias, I; Muñoz, M J; Montes, F; Perez, A; Gogin, A; Kolbasov, D; de la Torre, A

    2016-12-01

    African swine fever (ASF) has caused the swine industry of the Russian Federation substantial economic losses over the last 7 years, and the disease spread from there to a number of neighbouring countries. Wild boar has been involved in the spread of the disease both at local and at transboundary levels. Understanding ASF dynamics in wild boars is prerequisite to preventing the spread and to designing and applying effective surveillance and control plans. The reproductive ratio (R0 ) is an epidemiological indicator commonly used to quantify the extent of disease spread. Here, it was estimated in nine spatio-temporal clusters of ASF in wild boar cases in the Russian Federation (2007-2013). Clusters were defined by exploring the maximum distance of association of ASF cases using K Ripley analysis and spatio-temporal scan statistics. A maximum spatial association of 133 km in wild boar cases was identified which is within de the conventional radius of surveillance zone (100-150 km). The mean range value of R0  = 1.58 (1.13-3.77) was lower compared to values previously estimated for ASF transmission within farms but similar to early estimates between farm (R0  = 2-3), in domestic pigs using notification data in the Russian Federation. Results obtained provide quantitative knowledge on the epidemiology of ASF in wild boars in the Russian Federation. They identify the ASF transmission rate value in affected natural wild populations, for the first time, which could provide basis for modelling ASF transmission and suggest that current surveillance radius should be reviewed to make surveillance in wild nature more targeted and effective.

  11. The Fertilizing Role of African Dust in the Amazon Rainforest. A First Multiyear Assessment Based on Data from Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations

    SciTech Connect

    Yu, Hongbin; Chin, Mian; Yuan, Tianle; Bian, Huisheng; Remer, L. A.; Prospero, J.; Omar, Ali; Winker, D.; Yang, Yuekui; Zhang, Yan; Zhang, Zhibo; Zhao, Chun

    2015-03-18

    The productivity of the Amazon rainforest is constrained by the availability of nutrients, in particular phosphorus (P). Deposition of long-range transported African dust is recognized as a potentially important but poorly quantified source of phosphorus. This study provides a first multiyear satellite-based estimate of dust deposition into the Amazon Basin using three dimensional (3D) aerosol measurements over 2007-2013 from the Cloud-Aerosol Lidar with Orthogonal Polarization (CALIOP). The 7-year average of dust deposition into the Amazon Basin is estimated to be 28 (8~48) Tg a-1 or 29 (8~50) kg ha-1 a-1. The dust deposition shows significant interannual variation that is negatively correlated with the prior-year rainfall in the Sahel. The CALIOP-based multi-year mean estimate of dust deposition matches better with estimates from in-situ measurements and model simulations than a previous satellite-based estimate does. The closer agreement benefits from a more realistic geographic definition of the Amazon Basin and inclusion of meridional dust transport calculation in addition to the 3D nature of CALIOP aerosol measurements. The imported dust could provide about 0.022 (0.006~0.037) Tg P of phosphorus per year, equivalent to 23 (7~39) g P ha-1 a-1 to fertilize the Amazon rainforest. This out-of-Basin P input is comparable to the hydrological loss of P from the Basin, suggesting an important role of African dust in preventing phosphorus depletion on time scales of decades to centuries.

  12. Geochemical Treasure Hunt for Primary School Children

    NASA Astrophysics Data System (ADS)

    Tesmer, Maja; Frick, Daniel; Gerrits, Ruben; des GFZ-GeoWunderWerkstatt, Schülerlabor

    2017-04-01

    Actions) of the European Union's Seventh Framework Programme FP7/2007-2013/ under REA grant agreement n° [608069].

  13. One year of vertical wind profiles measurements at a Mediterranean coastal site of South Italy

    NASA Astrophysics Data System (ADS)

    Calidonna, Claudia Roberta; Avolio, Elenio; Federico, Stefano; Gullì, Daniel; Lo Feudo, Teresa; Sempreviva, Anna Maria

    2015-04-01

    In order to develop wind farms projects is challenging to site them on coastal areas both onshore and offshore as suitable sites. Developing projects need high quality databases under a wide range of atmospheric conditions or high resolution models that could resolve the effect of the coastal discontinuity in the surface properties. New parametrizations are important and high quality databases are also needed for formulating them. Ground-based remote sensing devices such as lidars have been shown to be functional for studying the evolution of the vertical wind structure coastal atmospheric boundary layer both on- and offshore. Here, we present results from a year of vertical wind profiles, wind speed and direction, monitoring programme at a site located in the Italian Calabria Region, Central Mediterranean, 600m from the Thyrrenian coastline, where a Lidar Doppler, ZephIr (ZephIr ltd) has been operative since July 2013. The lidar monitors wind speed and direction from 10m up to 300m at 10 vertical levels with an average of 10 minutes and it is supported by a metmast providing: Atmospheric Pressure, Solar Radiation, Precipitation, Relative Humidity, Temperature,Wind Speed and Direction at 10m. We present the characterization of wind profiles during one year period according to the time of the day to transition periods night/day/night classified relating the local scale, breeze scale, to the large scale conditions. The dataset is also functional for techniques for short-term prediction of wind for the renewable energy integration in the distribution grids. The site infrastructure is funded within the Project "Infrastructure of High Technology for Environmental and Climate Monitoring" (I-AMICA) (PONa3_00363) by the Italian National Operative Program (PON 2007-2013) and European Regional Development Fund. Real-time data are show on http://www.i-amica.it/i-amica/?page_id=1122.

  14. Three-dimensional particle-in-cell simulations of a plasma jet/cloud streaming across a transverse magnetic field

    NASA Astrophysics Data System (ADS)

    Voitcu, Gabriel; Echim, Marius

    2014-05-01

    The dynamics of collisionless plasma jets/clouds in magnetic field configurations typical for the terrestrial magnetotail and frontside magnetosheath is a topic of interest for understanding the physics of the magnetosphere and its interaction with the solar wind. The presence of high-speed jets in the frontside magnetosheath has been recently proved experimentally by Cluster and THEMIS spacecrafts. There is increasing evidence that the bursty bulk flows in the magnetotail have jet-like features. In the present paper we use fully electromagnetic 3D explicit particle-in-cell (PIC) simulations to investigate the interaction of a localized three-dimensional plasma element/jet/cloud with a transverse magnetic field. We consider a plasma jet/cloud that moves in vacuum and perpendicular to an ambient magnetic field. Ampère and Faraday's laws are used to compute the self-consistent electric and magnetic fields on a three-dimensional spatial grid having a step-size of the order of the Debye length and using a time-step that resolves the plasma frequency. The initial magnetic field inside the simulation domain is uniform and the plasma bulk velocity at the beginning of the simulation is normal to the magnetic field direction. The total time scale of the simulation is of the order of few ion Larmor periods. Space and time variations of the plasma parameters and of the electromagnetic field are analyzed and discussed. We emphasize non-MHD effects like the energy-dispersion signatures at the edges of the plasma element, similar to results previously reported by Voitcu and Echim (2012) using test-kinetic simulations. Acknowledgments: Research supported by the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement no. 313038/STORM, and a grant of the Romanian Ministry of National Education, CNCS - UEFISCDI, project number PN-II-ID-PCE-2012-4-0418.

  15. Super-resolution restoration applied to the characterisation of dynamic surface changes on the Martian surface

    NASA Astrophysics Data System (ADS)

    Tao, Yu; Muller, Jan-Peter

    2016-10-01

    Higher spatial resolution imaging data is always desirable to the international community of planetary scientists interested in improving understanding of surface formation processes. We have previously developed a novel Super-resolution restoration (SRR) technique using Gotcha sub-pixel matching [Shin & Muller, PR, 2012], orthorectification, segmentation, and 4th order PDE-TV, called GPT SRR [Tao & Muller, PSS, 2016]. This technique is able to restore 5cm-12.5cm near rover scale images (Navcam at a range of ≥5m) from multi-angle repeat-pass 25cm resolution MRO HiRISE images [Tao & Muller, ISPRS, 2016].We have successfully applied the GPT-SRR to the MER and MSL missions (http://www.progisweb.eu), as well as the alleged site of the Beagle-2 spacecraft (https://www.flickr.com/photos/uclnews/albums/72157667609698345). In this work, we further apply GPT-SRR on areas with known dynamic changes, including Recurring Slope Lineae (RSL), Gullies, and Polar Dune Flows. We restore static surface and meanwhile track the dynamic features to characterise the "change", including directions and speed of the changes. We also demonstrate that such repeat images can be used to image the MER-A rover stuck in the sands.AcknowledgementsThe research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under iMars grant agreement no. 607379 as well as partial funding from the STFC "MSSL Consolidated Grant" ST/K000977/1.

  16. Frequency of block displacements at the north pole of Mars based on HiRISE images

    NASA Astrophysics Data System (ADS)

    Fanara, Lida; Gwinner, Klaus; Hauber, Ernst; Oberst, Juergen

    2016-10-01

    We identify active block displacements at the foot of the steep north polar scarps of Mars and estimate the frequency of these events. This will help us improve our knowledge of the erosion rate and evolution of the north polar cap. Thousands of single-block movements or events involving multiple blocks have been captured within 10 years of repeated high resolution imaging of the north polar cap's margins by High Resolution Imaging Experiment (HiRISE). These blocks, which are up to a couple of cubic meters in size, become detached either from the North Polar Layered Deposits (NPLD) or the Basal Unit (BU) [1] and come to rest intact or after breaking up into smaller fragments. We detect the new blocks automatically in co-registered images taken at different times. For the co-registration we use Ames Stereo Pipeline [2] to produce HiRISE Digital Terrain Models (DTMs) and ortho-rectify the images on these DTMs. We focus on retrieving the frequency of the events as well as the sizes and shapes of the moved blocks. Our results suggest that rock falls are presently an important, regular recurring seasonal process for certain areas of the north polar scarps. Estimates of the volume of the mass movements and hence the erosion rate are supported by analysis of corresponding DTMs.The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under iMars grant agreement no 607379.References:[1] Russell et al., Landslide erosion rates of north polar layered deposit cliffs and the underlying basal unit, Eighth International Conference on Mars, 2014[2] Moratto et al., Ames Stereo Pipeline, NASA's Open Source Automated Stereogrammetry Software, LPSC, 2010

  17. Monitoring Mediterranean marine pollution using remote sensing and hydrodynamic modelling

    NASA Astrophysics Data System (ADS)

    La Loggia, Goffredo; Capodici, Fulvio; Ciraolo, Giuseppe; Drago, Aldo; Maltese, Antonino

    2011-11-01

    Human activities contaminate both coastal areas and open seas, even though impacts are different in terms of pollutants, ecosystems and recovery time. In particular, Mediterranean offshore pollution is mainly related to maritime transport of oil, accounting for 25% of the global maritime traffic and, during the last 25 years, for nearly 7% of the world oil accidents, thus causing serious biological impacts on both open sea and coastal zone habitats. This paper provides a general review of maritime pollution monitoring using integrated approaches of remote sensing and hydrodynamic modeling; focusing on the main results of the MAPRES (Marine pollution monitoring and detection by aerial surveillance and satellite images) research project on the synergistic use of remote sensing, forecasting, cleanup measures and environmental consequences. The paper also investigates techniques of oil spill detection using SAR images, presenting the first results of "Monitoring of marine pollution due to oil slick", a COSMO-SkyMed funded research project where X-band SAR constellation images provided by the Italian Space Agency are used. Finally, the prospect of using real time observations of marine surface conditions is presented through CALYPSO project (CALYPSO-HF Radar Monitoring System and Response against Marine Oil Spills in the Malta Channel), partly financed by the EU under the Operational Programme Italia-Malta 2007-2013. The project concerns the setting up of a permanent and fully operational HF radar observing system, capable of recording surface currents (in real-time with hourly updates) in the stretch of sea between Malta and Sicily. A combined use of collected data and numerical models, aims to optimize intervention and response in the case of marine oil spills.

  18. Development of Local Amplification Factors in the NEAM Region for Production of Regional Tsunami Hazard Maps

    NASA Astrophysics Data System (ADS)

    Harbitz, C. B.; Glimsdal, S.; Løvholt, F.; Orefice, S.; Romano, F.; Brizuela, B.; Lorito, S.; Hoechner, A.; Babeyko, A. Y.

    2016-12-01

    The standard way of estimating tsunami inundation is by applying numerical depth-averaged shallow-water run-up models. However, for a regional Probabilistic Tsunami Hazard Assessment (PTHA), applying such inundation models may be too time-consuming. A faster, yet less accurate procedure, is to relate the near-shore surface elevations at offshore points to maximum shoreline water levels by using a set of amplification factors based on the characteristics of the incident wave and the bathymetric slope. The surface elevation at the shoreline then acts as a rough approximation for the maximum inundation height or run-up height along the shoreline. An amplification-factor procedure based on a limited set of idealized broken shoreline segments has previously been applied to estimate the maximum inundation heights globally. Here, we present a study where this technique is developed further, by taking into account the local bathymetric profiles. We extract a large number of local bathymetric transects over a significant part of the North East Atlantic, the Mediterranean and connected seas (NEAM) region. For each bathymetric transect, we compute the wave amplification from an offshore control point to points close to the shoreline using a linear shallow-water model for waves of different period and polarity with a sinusoidal pulse wave as input. The amplification factors are then tabulated. We present maximum water levels from the amplification factor method, and compare these with results from conventional inundation models. Finally, we demonstrate how the amplification factor method can be convolved with PTHA results to provide regional tsunami hazard maps. This work has been supported by the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement 603839 (Project ASTARTE), and the TSUMAPS-NEAM Project (http://www.tsumapsneam.eu/), co-financed by the European Union Civil Protection Mechanism, Agreement Number: ECHO/SUB/2015/718568/PREV26.

  19. A dynamic landslide hazard assessment system for Central America and Hispaniola

    NASA Astrophysics Data System (ADS)

    Kirschbaum, D. B.; Stanley, T.; Simmons, J.

    2015-10-01

    Landslides pose a serious threat to life and property in Central America and the Caribbean Islands. In order to allow regionally coordinated situational awareness and disaster response, an online decision support system was created. At its core is a new flexible framework for evaluating potential landslide activity in near real time: Landslide Hazard Assessment for Situational Awareness. This framework was implemented in Central America and the Caribbean by integrating a regional susceptibility map and satellite-based rainfall estimates into a binary decision tree, considering both daily and antecedent rainfall. Using a regionally distributed, percentile-based threshold approach, the model outputs a pixel-by-pixel nowcast in near real time at a resolution of 30 arcsec to identify areas of moderate and high landslide hazard. The daily and antecedent rainfall thresholds in the model are calibrated using a subset of the Global Landslide Catalog in Central America available for 2007-2013. The model was then evaluated with data for 2014. Results suggest reasonable model skill over Central America and poorer performance over Hispaniola due primarily to the limited availability of calibration and validation data. The landslide model framework presented here demonstrates the capability to utilize globally available satellite products for regional landslide hazard assessment. It also provides a flexible framework to interchange the individual model components and adjust or calibrate thresholds based on access to new data and calibration sources. The availability of free satellite-based near real-time rainfall data allows the creation of similar models for any study area with a spatiotemporal record of landslide events. This method may also incorporate other hydrological or atmospheric variables such as numerical weather forecasts or satellite-based soil moisture estimates within this decision tree approach for improved hazard analysis.

  20. Analysis of the drought resilience of Andosols on southern Ecuadorian Andean páramos

    NASA Astrophysics Data System (ADS)

    Iñiguez, V.; Morales, O.; Cisneros, F.; Bauwens, W.; Wyseure, G.

    2015-11-01

    The neotropical Andean grasslands above 3500 m a.s.l. known as "páramo" offer remarkable ecological services for the Andean region. Most important is the water supply - of excellent quality - to many cities and villages established in the lowlands of the inter-Andean valleys and to the coast. However, the páramo ecosystem is under constant and increased threat by human activities and climate change. In this paper we study the resilience of its soils for drought periods during the period 2007-2013. In addition, field measurements and hydrological conceptual modelling at the catchment-scale are comparing two contrasting catchments in the southern Ecuadorian Andes. Both were intensively monitored during two and a half years (2010-2012) in order to analyse the temporal variability of the soil moisture storage. A typical catchment on the páramo at 3500 m a.s.l. was compared to a lower grassland one at 2600 m a.s.l. The main aim was to estimate the resilience capacity of the soils during a drought period and the recovery during a subsequent wet period. Local soil water content measurements in the top soil (first 30 cm) through TDR were used as a proxy for the catchment's average soil moisture storage. The local measurements were compared to the average soil water storage as estimated by the probabilistic soil moisture (PDM) model. This conceptual hydrological model with 5 parameters was calibrated and validated for both catchments. The study reveals the extraordinary resilience capacity of this type of shallow organic soils during the droughts in 2009 and 2010. During these droughts, the soil water content dropped from a normal value of about 0.80 to ~ 0.60 cm3 cm-3, while the recovery time was only two to three months.

  1. Production of Arctic Sea-ice Albedo by fusion of MISR and MODIS data

    NASA Astrophysics Data System (ADS)

    Kharbouche, Said; Muller, Jan-Peter

    2017-04-01

    We have combined data from the NASA MISR and MODIS spectro-radiometers to create a cloud-free albedo dataset specifically for sea-ice. The MISR (Multi-Angular Spectro-Radiometer) instrument on board Terra satellite has a unique ability to create high-quality Bidirectional Reflectance (BRF) over a 7 minute time interval per single overpass, thanks to its 9 cameras of different view angles (±70°,±60°,±45°,±26°). However, as MISR is limited to narrow spectral bands (443nm, 555nm, 670nm, 865nm), which is not sufficient to mask cloud effectively and robustly, we have used the sea-ice mask MOD09 product (Collection 6) from MODIS (Moderate resolution Imaging Spectoradiometer) instrument, which is also on board Terra satellite and acquiring data simultaneously. Only We have created a new and consistent sea-ice (for Arctic) albedo product that is daily, from 1st March to 22nd September for each and every year between 2000 to 2016 at two spatial grids, 1km x 1km and 5km x 5km in polar stereographic projection. Their analysis is described in a separate report [1]. References [1] Muller & Kharbouche, Variation of Arctic's Sea-ice Albedo between 2000 and 2016 by fusion of MISR and MODIS data. This conference. Acknowledgements This work was supported by www.QA4ECV.eu, a project of European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement no. 607405. We thank our colleagues at JPL and NASA LaRC for processing these data, especially Sebastian Val and Steve Protack.

  2. Retrospective analysis of Stevens-Johnson syndrome and toxic epidermal necrolysis in 87 Japanese patients--Treatment and outcome.

    PubMed

    Yamane, Yumiko; Matsukura, Setsuko; Watanabe, Yuko; Yamaguchi, Yukie; Nakamura, Kazuko; Kambara, Takeshi; Ikezawa, Zenro; Aihara, Michiko

    2016-01-01

    Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but severe adverse drug reactions with high mortality. To present the clinical characteristics of SJS and TEN in Japan and evaluate the efficacy of treatments, we retrospectively analyzed cases of SJS and TEN treated in 2 university hospitals during 2000-2013. Fifty-two cases of SJS (21 males and 31 females; average age, 55.1 years) and 35 cases of TEN (17 males and 18 females; average age, 56.6 years) were included in this study. Twenty-eight cases of SJS (53.8%) and all cases of TEN were caused by drugs. Hepatitis was the most common organ involvement in both SJS and TEN. Renal dysfunction, intestinal disorder, and respiratory disorder were also involved in some cases. The major complication was pneumonia and sepsis. All cases except for 3 cases were treated systemically with corticosteroids. Steroid pulse therapy was performed in 88.6% of TEN. Plasmapheresis and/or immunoglobulin therapy was combined with steroid therapy mainly in TEN after 2007. The mortality rate was 6.9% and the rates for SJS and TEN were 1.9% and 14.3%, respectively. These were much lower than predicted mortality according to a severity-of-illness scoring system for TEN prognosis (SCORTEN) score. When comparing the mortality rate between 2000-2006 and 2007-2013, it was decreased from 4.5% to 0.0% in SJS and from 22.2% to 5.3% in TEN. Treatment with steroid pulse therapy in combination with plasmapheresis and/or immunoglobulin therapy seems to have contributed to prognostic improvement in SJS/TEN. Copyright © 2015 The Authors. Production and hosting by Elsevier B.V. All rights reserved.

  3. The fertilizing role of African dust in the Amazon rainforest: A first multiyear assessment based on data from Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations

    NASA Astrophysics Data System (ADS)

    Yu, Hongbin; Chin, Mian; Yuan, Tianle; Bian, Huisheng; Remer, Lorraine A.; Prospero, Joseph M.; Omar, Ali; Winker, David; Yang, Yuekui; Zhang, Yan; Zhang, Zhibo; Zhao, Chun

    2015-03-01

    The productivity of the Amazon rainforest is constrained by the availability of nutrients, in particular phosphorus (P). Deposition of long-range transported African dust is recognized as a potentially important but poorly quantified source of phosphorus. This study provides a first multiyear satellite-based estimate of dust deposition into the Amazon Basin using three-dimensional (3-D) aerosol measurements over 2007-2013 from the Cloud-Aerosol Lidar with Orthogonal Polarization (CALIOP). The 7 year average of dust deposition into the Amazon Basin is estimated to be 28 (8-48) Tg a-1 or 29 (8-50) kg ha-1 a-1. The dust deposition shows significant interannual variation that is negatively correlated with the prior-year rainfall in the Sahel. The CALIOP-based multiyear mean estimate of dust deposition matches better with estimates from in situ measurements and model simulations than a previous satellite-based estimate does. The closer agreement benefits from a more realistic geographic definition of the Amazon Basin and inclusion of meridional dust transport calculation in addition to the 3-D nature of CALIOP aerosol measurements. The imported dust could provide about 0.022 (0.006-0.037) Tg P of phosphorus per year, equivalent to 23 (7-39) g P ha-1 a-1 to fertilize the Amazon rainforest. This out-of-basin phosphorus input is comparable to the hydrological loss of phosphorus from the basin, suggesting an important role of African dust in preventing phosphorus depletion on timescales of decades to centuries.

  4. Development of Local Amplification Factors in the NEAM Region for Production of Regional Tsunami Hazard Maps

    NASA Astrophysics Data System (ADS)

    Glimsdal, Sylfest; Løvholt, Finn; Bonnevie Harbitz, Carl; Orefice, Simone; Romano, Fabrizio; Brizuela, Beatriz; Lorito, Stefano; Hoechner, Andreas; Babeyko, Andrey

    2017-04-01

    The standard way of estimating tsunami inundation is by applying numerical depth-averaged shallow-water run-up models. However, for a regional Probabilistic Tsunami Hazard Assessment (PTHA), applying such inundation models may be too time-consuming. A faster, yet less accurate procedure, is to relate the near-shore surface elevations at offshore points to maximum shoreline water levels by using a set of amplification factors based on the characteristics of the incident wave and the bathymetric slope. The surface elevation at the shoreline then acts as a rough approximation for the maximum inundation height or run-up height along the shoreline. An amplification-factor procedure based on a limited set of idealized broken shoreline segments has previously been applied to estimate the maximum inundation heights globally. Here, we present a study where this technique is developed further, by taking into account the local bathymetric profiles. We extract a large number of local bathymetric transects over a significant part of the North East Atlantic, the Mediterranean and connected seas (NEAM region). For each bathymetric transect, we compute the wave amplification from an offshore control point to points close to the shoreline using a linear shallow-water model for waves of different period and polarity with a sinusoidal pulse wave as input. The amplification factors are then tabulated. We present maximum water levels from the amplification factor method, and compare these with results from conventional inundation models. Finally, we demonstrate how the amplification factor method can be convolved with PTHA results to provide regional tsunami hazard maps. This work has been supported by the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement 603839 (Project ASTARTE), and the TSUMAPS-NEAM Project (http://www.tsumapsneam.eu/), co-financed by the European Union Civil Protection Mechanism, Agreement Number: ECHO/SUB/2015/718568/PREV26.

  5. HIGH BODY MASS INDEX AMONG PATIENTS UNDERGOING HEMATOPOIETIC STEM CELL TRANSPLANTATION: RESULTS OF A CROSS-SECTIONAL EVALUATION OF NUTRITIONAL STATUS IN A PRIVATE HOSPITAL.

    PubMed

    Pereira, Andrea Z; Victor, Elivane S; Vidal Campregher, Paulo; Piovacari, Silvia M F; Bernardo Barban, Juliana S; Pedreira, Wilson L; Hamerschlak, Nelson

    2015-12-01

    nutritional status before hematopoietic stem cell transplantation (HSCT) affects prognosis: better nourished patients have shorter time to engraftment, while malnutrition is associated with increase of mortality rates, complications, medical costs, poor quality of life and hospitalization stay. Furthermore, underweight patients have increased risk of death in the early post- HSCT period, and non-relapse mortality is greater for those who are extremely underweight, overweight and obese. Obesity is associated with treatment-related toxicity, higher incidence of grade II-IV acute graft-versus- host disease (GVHD), infections and mortality. The objective of this study was to investigate the nutritional status of patients undergoing HSCT between 2007-2013 in a private hospital, by calculating the body mass index (BMI), to verify the prevalence of any nutritional imbalances, especially obesity. in this retrospective study, based on medical records, we analyzed data from all patients with malignant and nonmalignant diseases who underwent HSCT from January 2007 to February 2014 in the Hematology- Oncology and Bone Marrow Transplantation Center at a large, tertiary referral center in Brazil. a total of 257 cases were treated in the period and analyzed, of which 79% were aged up to 65 years old. Among these, 56% were overweight or obese. We observed a higher prevalence of obesity in elderly patients (P < 0.001). The mean BMI of the total sample was 26.4 kg/m2. BMI was significantly different between genders, with higher prevalence of overweight among men (P < 0.001). differently from other studies, our investigation has shown low rates of underweight and more overweight and obesity rates in men and elderly patients undergoing HSCT. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  6. Proposal for a probabilistic local level landslide hazard assessment model: The case of Suluktu, Kyrgyzstan

    NASA Astrophysics Data System (ADS)

    Vidar Vangelsten, Bjørn; Fornes, Petter; Cepeda, Jose Mauricio; Ekseth, Kristine Helene; Eidsvig, Unni; Ormukov, Cholponbek

    2015-04-01

    Landslides are a significant threat to human life and the built environment in many parts of Central Asia. To improve understanding of the magnitude of the threat and propose appropriate risk mitigation measures, landslide hazard mapping is needed both at regional and local level. Many different approaches for landslide hazard mapping exist depending on the scale and purpose of the analysis and what input data are available. This paper presents a probabilistic local scale landslide hazard mapping methodology for rainfall triggered landslides, adapted to the relatively dry climate found in South-Western Kyrgyzstan. The GIS based approach makes use of data on topography, geology, land use and soil characteristics to assess landslide susceptibility. Together with a selected rainfall scenario, these data are inserted into a triggering model based on an infinite slope formulation considering pore pressure and suction effects for unsaturated soils. A statistical model based on local landslide data has been developed to estimate landslide run-out. The model links the spatial extension of the landslide to land use and geological features. The model is tested and validated for the town of Suluktu in the Ferghana Valley in South-West Kyrgyzstan. Landslide hazard is estimated for the urban area and the surrounding hillsides. The case makes use of a range of data from different sources, both remote sensing data and in-situ data. Public global data sources are mixed with case specific data obtained from field work. The different data and models have various degrees of uncertainty. To account for this, the hazard model has been inserted into a Monte Carlo simulation framework to produce a probabilistic landslide hazard map identifying areas with high landslide exposure. The research leading to these results has received funding from the European Commission's Seventh Framework Programme [FP7/2007-2013], under grant agreement n° 312972 "Framework to integrate Space-based and in

  7. Association between serum folate and vitamin B-12 and outcomes of assisted reproductive technologies.

    PubMed

    Gaskins, Audrey J; Chiu, Yu-Han; Williams, Paige L; Ford, Jennifer B; Toth, Thomas L; Hauser, Russ; Chavarro, Jorge E

    2015-10-01

    Preconceptional folate and vitamin B-12 have been linked to beneficial reproductive outcomes in both natural pregnancies and those after assisted reproductive technology (ART) treatment. The objective of the study was to evaluate the associations of serum folate and vitamin B-12 with ART outcomes. This analysis included a random sample of 100 women (154 ART cycles) participating in a prospective cohort study [Environment and Reproductive Health (EARTH)] at the Massachusetts General Hospital Fertility Center (2007-2013). Serum folate and vitamin B-12 were measured in blood samples collected between days 3 and 9 of treatment. Generalized estimating equations with adjustment for age, BMI, and race were used to evaluate the association of serum folate and vitamin B-12 with ART outcomes. Women in the highest quartile of serum folate (>26.3 ng/mL) had 1.62 (95% CI: 0.99, 2.65) times the probability of live birth compared with women in the lowest quartile (<16.6 ng/mL). Women in the highest quartile of serum vitamin B-12 (>701 pg/mL) had 2.04 (95% CI: 1.14, 3.62) times the probability of live birth compared with women in the lowest quartile (<439 pg/mL). Suggestive evidence of an interaction was observed; women with serum folate and vitamin B-12 concentrations greater than the median had 1.92 (95% CI: 1.12, 3.29) times the probability of live birth compared with women with folate and vitamin B-12 concentrations less than or equal to the median. This translated into an adjusted difference in live birth rates of 26% (95% CI: 10%, 48%; P = 0.02). Higher serum concentrations of folate and vitamin B-12 before ART treatment were associated with higher live birth rates among a population exposed to folic acid fortification. This trial was registered at clinicaltrials.gov as NCT00011713. © 2015 American Society for Nutrition.

  8. Aerosol Optical Depth spatiotemporal variability and contribution of different aerosol types over Eastern Mediterranean

    NASA Astrophysics Data System (ADS)

    Georgoulias, Aristeidis K.; Alexandri, Georgia; Kourtidis, Konstantinos; Zanis, Prodromos; Pöschl, Ulrich; Lelieveld, Jos; Levy, Robert; Amiridis, Vassilis; Marinou, Eleni; Tsikerdekis, Athanasios; Pozzer, Andrea

    2015-04-01

    In this work, we study the aerosol spatiotemporal variability over the region of Eastern Mediterranean, for the time period 2000-2012, using a 0.1-degree gridded dataset compiled from level-2 MODIS TERRA and MODIS AQUA AOD550 and FMR550 data. A detailed validation of the AOD550 data was implemented using ground-based observations from the AERONET, also showing that the gridding methodology we followed allows for the detection of several local hot spots that cannot be seen using lower resolutions or level-3 data. By combining the MODIS data with data from other satellite sensors (TOMS, OMI), data from a global chemical-aerosol-transport model (GOCART), and reanalysis data from MACC and ERA-interim, we quantify the relative contribution of different aerosol types to the total AOD550 for the period of interest. For this reason, we developed an optimized algorithm for regional studies based on results from previous global studies. Over land, anthropogenic, dust, and fine-mode natural aerosols contribute to the total AOD550, while anthropogenic, dust and maritime AODs are calculated over the ocean. The dust AOD550 over the region was compared against dust AODs from the LIVAS CALIPSO product, showing a similar seasonal variability. Finally, we also look into the aerosol load short-term trends over the region for each aerosol type separately, the results being strongly affected by the selected time period. The research leading to these results has received funding from the European Social Fund (ESF) and national resources under the operational programme Education and Lifelong Learning (EdLL) within the framework of the Action "Supporting Postdoctoral Researchers" (QUADIEEMS project) and from the European Research Council under the European Union's Seventh Framework Programme (FP7/2007-2013)/ERC grant agreement no. 226144 (C8 project).

  9. Increasing rates of brain tumours in the Swedish national inpatient register and the causes of death register.

    PubMed

    Hardell, Lennart; Carlberg, Michael

    2015-04-03

    Radiofrequency emissions in the frequency range 30 kHz-300 GHz were evaluated to be Group 2B, i.e., "possibly", carcinogenic to humans by the International Agency for Research on Cancer (IARC) at WHO in May 2011. The Swedish Cancer Register has not shown increasing incidence of brain tumours in recent years and has been used to dismiss epidemiological evidence on a risk. In this study we used the Swedish National Inpatient Register (IPR) and Causes of Death Register (CDR) to further study the incidence comparing with the Cancer Register data for the time period 1998-2013 using joinpoint regression analysis. In the IPR we found a joinpoint in 2007 with Annual Percentage Change (APC) +4.25%, 95% CI +1.98, +6.57% during 2007-2013 for tumours of unknown type in the brain or CNS. In the CDR joinpoint regression found one joinpoint in 2008 with APC during 2008-2013 +22.60%, 95% CI +9.68, +37.03%. These tumour diagnoses would be based on clinical examination, mainly CT and/or MRI, but without histopathology or cytology. No statistically significant increasing incidence was found in the Swedish Cancer Register during these years. We postulate that a large part of brain tumours of unknown type are never reported to the Cancer Register. Furthermore, the frequency of diagnosis based on autopsy has declined substantially due to a general decline of autopsies in Sweden adding further to missing cases. We conclude that the Swedish Cancer Register is not reliable to be used to dismiss results in epidemiological studies on the use of wireless phones and brain tumour risk.

  10. Evaluating performances of simplified physically based landslide susceptibility models.

    NASA Astrophysics Data System (ADS)

    Capparelli, Giovanna; Formetta, Giuseppe; Versace, Pasquale

    2015-04-01

    Monitoring, Early Warning and Mitigation Along the Main Lifelines", CUP B31H11000370005, in the framework of the National Operational Program for "Research and Competitiveness" 2007-2013.

  11. Impact of irrigations on simulated convective activity over Central Greece: A high resolution study

    NASA Astrophysics Data System (ADS)

    Kotsopoulos, S.; Tegoulias, I.; Pytharoulis, I.; Kartsios, S.; Bampzelis, D.; Karacostas, T.

    2014-12-01

    The aim of this research is to investigate the impact of irrigations in the characteristics of convective activity simulated by the non-hydrostatic Weather Research and Forecasting model with the Advanced Research dynamic solver (WRF-ARW, version 3.5.1), under different upper air synoptic conditions in central Greece. To this end, 42 cases equally distributed under the six most frequent upper air synoptic conditions, which are associated with convective activity in the region of interest, were utilized considering two different soil moisture scenarios. In the first scenario, the model was initialized with the surface soil moisture of the ECMWF analysis data that usually does not take into account the modification of soil moisture due to agricultural activity in the area of interest. In the second scenario, the soil moisture in the upper soil layers of the study area was modified to the field capacity for the irrigated cropland. Three model domains, covering Europe, the Mediterranean Sea and northern Africa (d01), the wider area of Greece (d02) and central Greece - Thessaly region (d03) are used at horizontal grid-spacings of 15km, 5km and 1km respectively. The model numerical results indicate a strong dependence of convective spatiotemporal characteristics from the soil moisture difference between the two scenarios. Acknowledgements: This research is co-financed by the European Union (European Regional Development Fund) and Greek national funds, through the action "COOPERATION 2011: Partnerships of Production and Research Institutions in Focused Research and Technology Sectors" (contract number 11SYN_8_1088 - DAPHNE) in the framework of the operational programme "Competitiveness and Entrepreneurship" and Regions in Transition (OPC II, NSRF 2007-2013).

  12. Evaluation of numerical weather predictions performed in the context of the project DAPHNE

    NASA Astrophysics Data System (ADS)

    Tegoulias, Ioannis; Pytharoulis, Ioannis; Bampzelis, Dimitris; Karacostas, Theodore

    2014-05-01

    The region of Thessaly in central Greece is one of the main areas of agricultural production in Greece. Severe weather phenomena affect the agricultural production in this region with adverse effects for farmers and the national economy. For this reason the project DAPHNE aims at tackling the problem of drought by means of weather modification through the development of the necessary tools to support the application of a rainfall enhancement program. In the present study the numerical weather prediction system WRF-ARW is used, in order to assess its ability to represent extreme weather phenomena in the region of Thessaly. WRF is integrated in three domains covering Europe, Eastern Mediterranean and Central-Northern Greece (Thessaly and a large part of Macedonia) using telescoping nesting with grid spacing of 15km, 5km and 1.667km, respectively. The cases examined span throughout the transitional and warm period (April to September) of the years 2008 to 2013, including days with thunderstorm activity. Model results are evaluated against all available surface observations and radar products, taking into account the spatial characteristics and intensity of the storms. Preliminary results indicate a good level of agreement between the simulated and observed fields as far as the standard parameters (such as temperature, humidity and precipitation) are concerned. Moreover, the model generally exhibits a potential to represent the occurrence of the convective activity, but not its exact spatiotemporal characteristics. Acknowledgements This research work has been co-financed by the European Union (European Regional Development Fund) and Greek national funds, through the action "COOPERATION 2011: Partnerships of Production and Research Institutions in Focused Research and Technology Sectors" (contract number 11SYN_8_1088 - DAPHNE) in the framework of the operational programme "Competitiveness and Entrepreneurship" and Regions in Transition (OPC II, NSRF 2007-2013)

  13. A polymorphism in the promoter region of the selenoprotein S gene (SEPS1) contributes to Hashimoto's thyroiditis susceptibility.

    PubMed

    Santos, Liliana R; Durães, Cecília; Mendes, Adélia; Prazeres, Hugo; Alvelos, Maria Inês; Moreira, Carla Susete; Canedo, Paulo; Esteves, César; Neves, Celestino; Carvalho, Davide; Sobrinho-Simões, Manuel; Soares, Paula

    2014-04-01

    The association between selenium and inflammation and the relevance of selenoproteins in follicular thyroid cell physiology have pointed to a putative role of selenoproteins in the pathogenesis of autoimmune thyroid diseases. The aim of this study was to evaluate the role of a promoter variation in SEPS1, the selenoprotein S gene, in the risk for developing Hashimoto's thyroiditis (HT). A case-control study was performed to assess the association of genetic variation in the SEPS1 gene (SEPS1 -105G/A single-nucleotide polymorphism, rs28665122) and HT. The study was conducted in north Portugal, Porto, in the period of 2007-2013. A total of 997 individuals comprising 481 HT patients and 516 unrelated controls were enrolled in the study. Genetic variants were discriminated by real-time PCR using TaqMan single-nucleotide polymorphism genotyping assays. There is a significant association between the SEPS1 -105 GA and AA genotypes and HT [odds ratio (OR) 2.24, confidence interval (CI) 1.67-3.02, P < 5.0 × 10(-7), and OR 2.08, CI 1.09-3.97, P = .0268, respectively]. The A allele carriers are in higher proportion in the patient group than in the control population (46.2% vs 28.1%, P < 5.0 × 10(-7)) with an OR (CI) of 2.22 (1.67-2.97). The proportion of patients carrying the A allele is significantly higher in male patients with HT, representing a 3.94 times increased risk (P = 7.9 × 10(-3)). Our findings support the existence of a link between SEPS1 promoter genetic variation and HT risk.

  14. Turbulent amplification of magnetic fields in the laboratory

    NASA Astrophysics Data System (ADS)

    Gregori, Gianluca

    2014-10-01

    Magnetic fields exist ubiquitously in the Universe, as revealed by either diffuse radio-synchrotron emission, or Faraday rotation observations, with strengths from a few nG to tens of μG. The energy density of these fields is typically comparable to the energy density of the fluid motions of the plasma in which they are embedded, making magnetic fields essential players in the dynamics of the luminous matter in the Universe. At present, the origin and the distribution of the magnetic fields are far from being understood. The standard model for the origin of these intergalactic magnetic fields is through the amplification of seed fields via turbulent processes to the level consistent with current observations. We have conducted a series of laboratory experiments using high power laser facilities to exploit the scale invariance of the magneto-hydrodynamics equations. While the scaling is not perfect (e.g., in what concerns dissipation coefficients such as resistivity or viscosity), the similarity is sufficiently close to make such experiments interesting - and the results have been showing up the fundamental physical process at play. Our results indicate the magnetic field is indeed amplified by turbulent mechanisms. We relate our findings with processes occurring in supernova remnants and in cluster of galaxies. These experiments provide an example of magnetic field amplification by turbulence in plasmas, a physical process thought to occur in many astrophysical phenomena. The research leading to these results has received funding from the European Research Council under the European Community's Seventh Framework Programme (FP7/2007-2013)/ERC Grant Agreement No. 256973.

  15. Geophysical techniques in the historical center of Venice (Italy): preliminary results from HVSR and multichannel analysis of surface waves

    NASA Astrophysics Data System (ADS)

    Trevisani, Sebastiano; Rocca, Michele; Boaga, Jacopo

    2014-05-01

    This presentation aims to outline the preliminary findings related to an extensive seismic survey conducted in the historical center of Venice, Italy. The survey was conducted via noninvasive and low-cost seismic techniques based on surface waves analysis and microtremor methods, mainly using single station horizontal to vertical spectral ratio techninques (HVSR) and multichannel analysis of surface waves in passive (ReMI) and active (MASW) configurations. The importance and the fragility of the cultural heritage of Venice, coupled with its peculiar geological and geotechnical characteristics, stress the importance of a good knowledge of its geological architecture and seismic characteristics as an opportunity to improve restoration and conservation planning. Even if Venice is located in a relatively low seismic hazard zone, a local characterization of soil resonance frequencies and surficial shear waves velocities could improve the planning of engineering interventions, furnishing important information on possible local effects related to seismic amplification and possible coupling within buildings and soil resonance frequencies. In the specific we collected more than 50 HVSR single station noise measurements and several passive and active multichannel analysis of surface waves located in the historical center. In this work we report the characteristics of the conducted seismic surveys (instrumentation, sampling geometry, etc.) and the preliminary findings of our analysis. Moreover, we discuss briefly the practical issues, mainly of logistic nature, of conducting this kind of surveys in a peculiar and crowed historical center as represented by Venice urban contest. Acknowledgments Instrumentation acquired in relation to the project co-financed by Regione Veneto, POR-CRO, FESR, 2007-2013, action 1.1.1. "Supporto ad attività di ricerca, processi e reti di innovazione e alla creazione di imprese in settori a elevato contenuto tecnologico"

  16. A dynamic landslide hazard assessment system for Central America and Hispaniola

    NASA Astrophysics Data System (ADS)

    Kirschbaum, D. B.; Stanley, T.; Simmons, J.

    2015-04-01

    Landslides pose a serious threat to life and property in Central America and the Caribbean Islands. In order to allow regionally coordinated situational awareness and disaster response, an online decision support system was created. At its core is a new flexible framework for evaluating potential landslide activity in near real-time: Landslide Hazard Assessment for Situational Awareness. This framework was implemented in Central America and the Caribbean by integrating a regional susceptibility map and satellite-based rainfall estimates into a binary decision tree, considering both daily and antecedent rainfall. Using a regionally distributed, percentile-based threshold approach, the model outputs a pixel-by-pixel nowcast in near real-time at a resolution of 30 arcsec to identify areas of moderate and high landslide hazard. The daily and antecedent rainfall thresholds in the model are calibrated using a subset of the Global Landslide Catalog in Central America available for 2007-2013. The model was then evaluated with data for 2014. Results suggest reasonable model skill over Central America and poorer performance over Hispaniola, due primarily to the limited availability of calibration and validation data. The landslide model framework presented here demonstrates the capability to utilize globally available satellite products for regional landslide hazard assessment. It also provides a flexible framework to interchange the indiviual model components and adjust or calibrate thresholds based on access to new data and calibration sources. The availability of free, satellite-based near real-time rainfall data allows the creation of similar models for any study area with a spatiotemporal record of landslide events. This method may also incorporate other hydrological or atmospheric variables such as numerical weather forecasts or satellite-based soil moisture estimates within this decision tree approach for improved hazard analysis.

  17. [Effect evaluation of a 2 dose varicella vaccine immunization strategy implemented to control outbreaks in school and kindergarten settings].

    PubMed

    Suo, Luodan; Li, Juan; Zhao, Dan; Yang, Fan; Liu, Weixiang; Wu, Jiang; Pang, Xinghuo; Deng, Ying; Lu, Li

    2015-06-01

    To evaluate the effect of outbreaks control in school settings after a 2 dose varicella vaccine immunization strategy implemented in Beijing. Epidemiological data of varicella outbreaks in school and kindergarten settings, which were reported by all 16 districts (county) during 2007-2013 according to the technical management norms of Beijing, was collected. The first dose and second dose varicella vaccine coverage rate of eligible children after the 2 dose varicella vaccine immunization strategy implementation were estimated through BJIIMS. Based on above we analyzed the changes of outbreak quantity, case quantity and the distribution characteristics between the pre-adjustment era (2007-2011 years) and late adjustment era (2013) of the 2 dose immunization strategy. In pre-adjustment era (2007-2011 years), an average of 74 (95% CI: 60-89) outbreaks was reported and 964 (95% CI: 812-1 116) cases were involved per year. In late adjustment era (2013): Outbreaks (35) declined 52.7%, involved cases (371) declined 61.5%; Outbreaks epidemic duration shortened from 22 days of pre-adjustment era to 18 days; Outbreaks involved 10-24 cases declined 64.7% (from 34 to 12); Outbreaks involved ≥ 25 cases declined 71.4% (from 7 to 2); Outbreaks of different school type as well as different regions without exception declined dramatically. Cumulative one-dose vaccine coverage in children of 2-6 yr of age was 89.6% (812 859/907 579), and cumulative second-dose vaccine coverage in children of 4-7 yr of age was 44.3% (289 764/647 732). Implementation of a 2 dose varicella vaccine immunization strategy effectively controlled outbreaks in school and kindergarten settings.

  18. Validation of family cancer history data in high-risk families: the influence of cancer site, ethnicity, kinship degree, and multiple family reporters.

    PubMed

    Tehranifar, Parisa; Wu, Hui-Chen; Shriver, Tom; Cloud, Ann J; Terry, Mary Beth

    2015-02-01

    Information on family cancer history (FCH) is often collected for first-degree relatives, but more extensive FCH information is critical for greater accuracy in risk assessment. Using self-reported diagnosis of cancer as the gold standard, we examined differences in the sensitivity and specificity of relative-reported FCH by cancer site, race/ethnicity, language preference, and kinship degree (1,524 individuals from 557 families; average number of relatives per family = 2.7). We evaluated the impact of FCH data collected in 2007-2013 from multiple relatives by comparing mean values and proportions for the number of relatives with any cancer, breast cancer, or ovarian cancer as reported by a single relative and by multiple relatives in the same family. The sensitivity of FCH was lower in Hispanics, Spanish-speaking persons, and third-degree relatives (e.g., for all cancers, sensitivities were 80.7%, 87.4%, and 91.0% for third-, second-, and first-degree relatives, respectively). FCH reported by multiple relatives included a higher number of relatives with cancer than the number reported by a single relative (e.g., mean increase of 1.2 relatives with any cancer), with more relatives diagnosed with any cancer, breast cancer, and ovarian cancer in 52%, 36% and 12% of families, respectively. Collection of FCH data from multiple relatives may provide a more comprehensive picture of FCH and may potentially improve risk assessment and preventive care. © The Author 2015. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  19. Incidence of and risk factors for surgical site infections in women undergoing hysterectomy for endometrial carcinoma.

    PubMed

    Tuomi, Taru; Pasanen, Annukka; Leminen, Arto; Bützow, Ralf; Loukovaara, Mikko

    2016-04-01

    The purpose of this study was to determine the incidence of, and risk factors for, surgical site infections in a contemporary cohort of women with endometrial carcinoma. We retrospectively studied 1164 women treated for endometrial carcinoma by hysterectomy at a single institution in 2007-2013. In all, 912 women (78.4%) had minimally invasive hysterectomy. Data on surgical site infections were collected from medical records. Univariate and multivariate analyses were used to identify risk factors for incisional and organ/space infections. Ninety-four women (8.1%) were diagnosed with a surgical site infection. Twenty women (1.7%) had an incisional infection and 74 (6.4%) had an organ/space infection. The associations of 17 clinico-pathologic and surgical variables were tested by univariate analyses. Those variables that were identified as potential risk factors in univariate analyses (p < 0.15) were used in logistic regression models with incisional and organ/space infections as dependent variables. Obesity (body mass index ≥ 30 kg/m(2)), diabetes, and long operative time (>80th centile) were independently associated with a higher risk of incisional infection, whereas minimally invasive surgery was associated with a smaller risk. Smoking, conversion to laparotomy, and lymphadenectomy were associated with a higher risk of organ/space infection. Organ/space infections comprised the majority of surgical site infections. Risk factors for incisional and organ/space infections differed. Minimally invasive hysterectomy was associated with a smaller risk of incisional infections but not of organ/space infections. © 2015 Nordic Federation of Societies of Obstetrics and Gynecology.

  20. Comparison of mercury concentrations measured at several sites in the Southern Hemisphere

    NASA Astrophysics Data System (ADS)

    Slemr, F.; Angot, H.; Dommergue, A.; Magand, O.; Barret, M.; Weigelt, A.; Ebinghaus, R.; Brunke, E.-G.; Pfaffhuber, K.; Edwards, G.; Howard, D.; Powell, J.; Keywood, M.; Wang, F.

    2014-12-01

    Our knowledge of the distribution of mercury concentrations in air of the Southern Hemisphere was until recently based mostly on intermittent measurements made during ship cruises. In the last few years continuous mercury monitoring has commenced at several sites in the Southern Hemisphere providing new and more refined information. In this paper we compare mercury measurements at several sites in the Southern Hemisphere made over a period of at least one year at each location. Averages of monthly medians show similar although small seasonal variations at both Cape Point and Amsterdam Island. A pronounced seasonal variation at Troll Research Station in Antarctica is due to frequent mercury depletion events in the austral spring. Due to large scatter and large standard deviations of monthly average median mercury concentrations at Cape Grim no systematic seasonal variation could be found there. Nevertheless, the annual average mercury concentrations at all sites during the 2007-2013 period varied only between 0.85 and 1.05 ng m-3. Part of this variability is likely due to systematic measurement uncertainties which we propose can be further reduced by improved calibration procedures. We conclude that mercury is much more uniformly distributed throughout the Southern Hemisphere than the distributions suggested by measurements made onboard ships. This finding implies (a) that trends observed at one or a few sites in the Southern Hemisphere are likely to be representative for the whole hemisphere, and (b) that smaller trends can be detected in shorter time periods. We also report a change of the trend sign at Cape Point from decreasing mercury concentrations in 1996-2004 to increasing concentrations since 2007.

  1. Fingerprint of the atmospheric deposition on the biogeochemical functioning in the Mediterranean Sea - Evolution since the preindustrial era and projections

    NASA Astrophysics Data System (ADS)

    Christodoulaki, Sylvia; Petihakis, George; Mihalopoulos, Nikolaos; Tsiaras, Kostas; Triantafyllou, George; Kanakidou, Maria

    2017-04-01

    The atmospheric deposition of trace elements in the marine environment plays a major role in low-nutrient low-chlorophyll (LNLC) regions, such as the Mediterranean Sea. Particularly the deposition of nitrogen (mainly nitrate and ammonium) and phosphorous (phosphate) represents an important source of essential nutrients for the growth of phytoplankton and bacteria, enhancing the marine productivity in these oligotrophic areas. In this study we investigate how the increase in atmospheric deposition of N over the past 1.5 century, together with a smaller increase in atmospheric P deposition onto the surface seawater, affected the nutrient stoichiometry and the marine ecosystem in the Eastern Mediterranean Sea and how this impact will change in the near future. To this end, and in order to understand the atmospheric and marine processes that regulate the effects of atmospheric deposition in the marine ecosystem and the N/P ratio as well as its temporal evolution in the Eastern Mediterranean, a 1-D coupled physical- biogeochemical model is used. The model is forced by observations of atmospheric deposition fluxes at Crete, while for the hindcast (1860) and forecast (2030) simulations, the changes in atmospheric deposition calculated by global chemistry- transport models are applied to the present-day observed fluxes. Then, a coupled 3-D hydrodynamic/biogeochemical model that is currently operational within the POSEIDON forecast system, forced by the TM4-ECPL global atmospheric chemistry transport model, is implemented at Mediterranean basin scale. Both the 1D and the 3D models show that the atmospheric deposition of N and P is capable of explaining the observed west-to-east gradient of N/P ratio in the sea. Impacts of atmospheric deposition of N and P on the marine carbon and nutrients cycles are investigated and discussed. This work has been supported by Thales - ADAMANT project (ESF - NSRF 2007- 2013).

  2. 12th European VLBI Network Symposium and Users Meeting

    NASA Astrophysics Data System (ADS)

    Tarchi, Andrea; Giroletti, Marcello; Feretti, Luigina

    The Istituto di Radioastronomia (IRA) di Bologna and the Osservatorio Astronomico di Cagliari (OAC), on behalf of the European VLBI Consortium, hosted the 12th European VLBI Network (EVN) Symposium and Users Meeting. The Conference was held from 7th to 10th of October at the Hotel Regina Margherita, in the center of Cagliari. The latest scientific results and technical developments from VLBI, and, in particular, e-VLBI and space-VLBI (RadioAstron) outcomes were reported. The timing of this meeting coincided with the first successful observational tests of the Sardinia Radio Telescopes within the EVN, and with a number of results from new and upgraded radio facilities around the globe, such as e-MERLIN, ALMA, and the SKA pathfinders. The symposium was attended by 133 participants from all over the world, with the Asian community represented by more than 20 colleagues. The program of the meeting consisted of 70 oral contributions (including 8 invited speakers) and 50 poster that covered a very wide range of VLBI topics both in galactic and extragalactic astrophysics (e.g., AGN, stellar evolution from birth to death, astrometry, and planetary science) as well as technological developments and future international collaborations. The scientific program also included a visit to the 64-m Sardinia Radio Telescope (SRT) and the EVN Users Meeting, where astronomers have provided useful feedback on various matters regarding EVN operations. The research leading to these results has received funding from the European Commission Seventh Framework Programme (FP/2007-2013) under grant agreement No 283393 (RadioNet3). EDITORIAL BOARD: Andrea Tarchi, Marcello Giroletti, Luigina Feretti

  3. Mental Health Services Utilization and Expenditures Among Children Enrolled in Employer-Sponsored Health Plans.

    PubMed

    Walter, Angela Wangari; Yuan, Yiyang; Cabral, Howard J

    2017-05-01

    Mental illness in children increases the risk of developing mental health disorders in adulthood, and reduces physical and emotional well-being across the life course. The Mental Health Parity and Addiction Equity Act (MHPAEA, 2008) aimed to improve access to mental health treatment by requiring employer-sponsored health plans to include insurance coverage for behavioral health services. Investigators used IBM Watson/Truven Analytics MarketScan claims data (2007-2013) to examine: (1) the distribution of mental illness; (2) trends in utilization and out-of-pocket expenditures; and (3) the overall effect of the MHPAEA on mental health services utilization and out-of-pocket expenditures among privately-insured children aged 3 to 17 with mental health disorders. Multivariate Poisson regression and linear regression modeling techniques were used. Mental health services use for outpatient behavioral health therapy (BHT) was higher in the years after the implementation of the MHPAEA (2010-2013). Specifically, before the MHPAEA implementation, the annual total visits for BHT provided by mental health physicians were 17.1% lower and 2.5% lower for BHT by mental health professionals, compared to years when MHPAEA was in effect. Children covered by consumer-driven and high-deductible plans had significantly higher out-of-pocket expenditures for BHT compared to those enrolled PPOs. Our findings demonstrate increased mental health services use and higher out-of-pocket costs per outpatient visit after implementation of the MHPAEA. As consumer-driven and high-deductible health plans continue to grow, enrollees need to be cognizant of the impact of health insurance benefit designs on health services offered in these plans. Copyright © 2017 by the American Academy of Pediatrics.

  4. Assessment of ASTER data for forest inventory in Canary Islands

    NASA Astrophysics Data System (ADS)

    Alonso-Benito, Alfonso; Arbelo, Manuel; Hernandez-Leal, Pedro A.; González-Calvo, Alejandro; Labrador Garcia, Mauricio

    To understand and evaluate the forest structural attributes, forest inventories are conducted, which are costly and lengthy in time. Since the last 10-15 years there has been examining the possibility of using remote sensing data, to save costs and cheapen the process. One of the aims of SATELMAC, a project PCT-MAC 2007-2013 co-financing with FEDER funds, is to automate the forest inventory in Canary Islands using satellite images. In this study, Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) data were used to estimate forest structure of the endemic vegetal specie, Pinus canariensis, located on the island of Tenerife (Spain). The forest structural attributes analyzed have been volume, basal area, stem per hectare and tree height. ASTER is an imaging instrument flying on Terra, a satellite launched in December 1999 as part of NASA's Earth Observing System. ASTER data were used because it have relatively high spatial resolution in the three visible and near-infrared bands (15 m) and in the six spectral bands (30 m) in the shortwave-IR region. To identify the vegetation index that is most suitable to use, about specific forest structural attributes in our study area, we assess the ability of different spectral indices: Normalized Difference Vegetation Index, Transformed Soil Adjusted Vegetation Index, Modified Soil adjusted Vegetation Index, Perpendicular Vegetation Index and Reduced Simple Ratio. The information provided by the ASTER data has been supplemented by the Third National Forest Inventory (III NFI) and field data. The results are analyzed statistically in order to see the degree of correlation (R2) and the mean square error (RMSE) of the values studied.

  5. Genetic and non-genetic factors affecting morphometry of Sirohi goats

    PubMed Central

    Dudhe, S. D.; Yadav, S. B. S.; Nagda, R. K.; Pannu, Urmila; Gahlot, G. C.

    2015-01-01

    Aim: The aim was to estimate genetic and non-genetic factors affecting morphometric traits of Sirohi goats under field condition. Materials and Methods: The detailed information of all animals on body measurements at birth, 3, 6, 9, and 12 months of age was collected from farmer’s flock under field condition born during 2007-2013 to analyze the effect of genetic and non-genetic factors. The least squares maximum likelihood program was used to estimate genetic and non-genetic parameters affecting morphometric traits. Results and Discussion: Effect of sire, cluster, year of birth, and sex was found to be highly significant (p<0.01) on all three morphometric traits, parity was highly significant (p<0.01) for body height (BH) and body girth (BG) at birth. The h2 estimates for morphometric traits ranged among 0.528±0.163 to 0.709±0.144 for BH, 0.408±0.159 to 0.605±0.192 for body length (BL), and 0.503±0.197 to 0.695±0.161 for BG. Conclusion: The effect of sire was highly significant (p<0.01) and also h² estimate of all morphometric traits were medium to high; therefore, it could be concluded on the basis of present findings that animals with higher body measurements at initial phases of growth will perform better with respect to even body weight traits at later stages of growth. PMID:27047043

  6. Ice nucleating particles from a large-scale sampling network: insight into geographic and temporal variability

    NASA Astrophysics Data System (ADS)

    Schrod, Jann; Weber, Daniel; Thomson, Erik S.; Pöhlker, Christopher; Saturno, Jorge; Artaxo, Paulo; Curtius, Joachim; Bingemer, Heinz

    2017-04-01

    The number concentration of ice nucleating particles (INP) is an important, yet under quantified atmospheric parameter. The temporal and geographic extent of observations worldwide remains relatively small, with many regions of the world (even whole continents and oceans), almost completely unrepresented by observational data. Measurements at pristine sites are particularly rare, but all the more valuable because such observations are necessary to estimate the pre-industrial baseline of aerosol and cloud related parameters that are needed to better understand the climate system and forecast future scenarios. As a partner of BACCHUS we began in September 2014 to operate an INP measurement network of four sampling stations, with a global geographic distribution. The stations are located at unique sites reaching from the Arctic to the equator: the Amazonian Tall Tower Observatory ATTO in Brazil, the Observatoire Volcanologique et Sismologique on the island of Martinique in the Caribbean Sea, the Zeppelin Observatory at Svalbard in the Norwegian Arctic and the Taunus Observatory near Frankfurt, Germany. Since 2014 samples were collected regularly by electrostatic precipitation of aerosol particles onto silicon substrates. The INP on the substrate are activated and analyzed in the isothermal static diffusion chamber FRIDGE at temperatures between -20°C and -30°C and relative humidity with respect to ice from 115 to 135%. Here we present data from the years 2015 and 2016 from this novel INP network and from selected campaign-based measurements from remote sites, including the Mt. Kenya GAW station. Acknowledgements The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) project BACCHUS under grant agreement No 603445 and the Deutsche Forschungsgemeinschaft (DFG) under the Research Unit FOR 1525 (INUIT).

  7. Clinical encounters in tactical medicine: a mission-specific analysis of the Maryland State Police experience.

    PubMed

    Levy, Matthew J; Smith, Rebecca; Gerold, Kevin B; Alves, Donald W; Tang, Nelson

    2014-01-01

    The Maryland State Police (MSP) Tactical Medical Unit (TMU) provides tactical emergency medical support (TEMS) through the deployment of specially trained state trooper tactical paramedics. The MSP TMU maintains an operational database of all mission related medical activity. This information constitutes a robust dataset derived from real world operational medicine experiences. A retrospective analysis of de-identified entries from the MSP TMU operational response database was performed for the 5-year period of 2007?2013. A summative analysis of missions, as well as a subgroup analysis of types of patients encountered, was performed to further characterize patient encounters based on the type of law enforcement tactical mission. Analysis was performed on 1,042 tactical missions, of which there were 367 total patient encounters during the study period. The majority (67%; 246/367) of patients encountered were law enforcement tactical team personnel. The most frequently occurring mission, by type, was high-risk warrant service, accounting for 45% (470/1,042) of all missions in this series. Law enforcement training support missions comprised 25% (259/1,042), and 15% (157/1,042) of all missions in the database were medical standbys for law enforcement operations. The highest number of patient contacts were associated with training activities, resulting in 29% (108/367) of clinical encounters. The next most common mission associated with patient encounters was high-risk warrant service (24%; 88/367). The 5-year analysis conducted in this study represents the largest known retrospective assessment of a state police tactical medical program. Training activities resulted in the highest number of patient encounters by this program, with law enforcement/tactical team personnel comprising the majority of patient encounters. The majority of chief complaints encountered were non?life threatening and reinforce the need for expanded scope of practice training and enhanced

  8. Epidemiological analysis of diseases of children and adolescents requiring neurological and mobility rehabilitation in the Świętokrzyskie Rehabilitation Center in Czarniecka Góra, Poland.

    PubMed

    Grabowski, Marek L; Kosińska, Bożena; Knap, Józef P; Lewandowski, Zbigniew

    2016-06-02

    Epidemiological analysis of the dynamics of admissions and patient characteristics is presented concerning 5,955 children and adolescents (3-18 years of age) hospitalized in 2007-2013 with neurological and mobility diseases in Świętokrzyskie Rehabilitation Centre (ŚRC) in southern Poland. Within the period of 7 years, 18,647 patients were admitted to the ŚRC, of whom 9,546 were admitted to the daily ward and 9,109 to the stationary wards. 5,955 were children and adolescents aged 3-18, 1,499 were children aged 3-13 and almost three times more were patients aged 14-18. The correlation between the number of admissions in each year and the number of those hospitalized depending on the age and diagnosis was examined. In the discussed period, in both age ranges, the group of deforming dorsopathies dominated, while cerebral palsy was the second most common cause of hospitalization, and the and post-traumatic disorder the smallest number. In the diagnoses of cerebral palsy and post-traumatic disease, boys constituted most of the hospitalized. In contrast, girls dominated in the group of deforming dorsopathies. Analysis of the material of 5,955 patients revealed a number of quantitative data which assisted in the analysis of the epidemiological situation of this group of diseases - necessary for the planning of highly specialized treatment and rehabilitation. The greatest needs in terms of admissions to the ŚRC concerned the group of adolescents aged 14-18. The results of combined rehabilitation indicated the full use of places in the Świętokrzyskie Rehabilitation Center and also indicated the need for similar provincial and even regional centres.

  9. Borderless Geospatial Web (bolegweb)

    NASA Astrophysics Data System (ADS)

    Cetl, V.; Kliment, T.; Kliment, M.

    2016-06-01

    The effective access and use of geospatial information (GI) resources acquires a critical value of importance in modern knowledge based society. Standard web services defined by Open Geospatial Consortium (OGC) are frequently used within the implementations of spatial data infrastructures (SDIs) to facilitate discovery and use of geospatial data. This data is stored in databases located in a layer, called the invisible web, thus are ignored by search engines. SDI uses a catalogue (discovery) service for the web as a gateway to the GI world through the metadata defined by ISO standards, which are structurally diverse to OGC metadata. Therefore, a crosswalk needs to be implemented to bridge the OGC resources discovered on mainstream web with those documented by metadata in an SDI to enrich its information extent. A public global wide and user friendly portal of OGC resources available on the web ensures and enhances the use of GI within a multidisciplinary context and bridges the geospatial web from the end-user perspective, thus opens its borders to everybody. Project "Crosswalking the layers of geospatial information resources to enable a borderless geospatial web" with the acronym BOLEGWEB is ongoing as a postdoctoral research project at the Faculty of Geodesy, University of Zagreb in Croatia (http://bolegweb.geof.unizg.hr/). The research leading to the results of the project has received funding from the European Union Seventh Framework Programme (FP7 2007-2013) under Marie Curie FP7-PEOPLE-2011-COFUND. The project started in the November 2014 and is planned to be finished by the end of 2016. This paper provides an overview of the project, research questions and methodology, so far achieved results and future steps.

  10. A case-control study evaluating the role of internet meet-up sites and mobile telephone applications in influencing a syphilis outbreak: Multnomah County, Oregon, USA 2014.

    PubMed

    DeSilva, Malini; Hedberg, Katrina; Robinson, Byron; Toevs, Kim; Neblett-Fanfair, Robyn; Petrosky, Emiko; Hariri, Susan; Schafer, Sean

    2016-08-01

    Early syphilis in Multnomah County, Oregon, USA, increased 16-fold during 2007-2013. Cases predominantly occurred among men who have sex with men (MSM); 55% were HIV coinfected. We conducted a case-control study to evaluate the association between meeting sex partners online and early syphilis. Cases subjects (cases) were Multnomah County resident, English speaking, MSM, aged ≥18 years with laboratory-confirmed early syphilis reported 1 January to 31 December 2013. We recruited two MSM controls subjects (controls) per case, frequency matched by HIV status and age. Participants completed self-administered questionnaires. We performed multivariable logistic regression. Seventy per cent (40/57) of cases and 42% (50/119) of controls met partners online (p<0.001). Cases more frequently met partners online (adjusted OR (aOR)=3.0; 95% CI 1.2 to 6.7), controlling for presumptive confounders. Cases reported more partners than controls (medians 5, 2; p<0.001). When including number of partners, aOR decreased to 1.4 (95% CI 0.5 to 3.9). Early syphilis was associated with meeting partners online. We believe this association may be related to number of sex partners acting as an intermediate variable between use of online resources to meet sex partners and early syphilis. Online meet-up sites might represent areas for public health interventions targeting at-risk individuals. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  11. RISICO: an adaptation of FWI to the Mediterranean environment

    NASA Astrophysics Data System (ADS)

    Fiorucci, Paolo; D'Andrea, Mirko; Turco, Marco

    2015-04-01

    The RISICO system provides the Italian Civil Protection Department (DPC) with daily wildland fire risk forecast maps relevant to the whole national territory since 2003. The structure of RISICO is conceptually similar to the Canadian Fire Weather Index. This index is used almost everywhere in the world and it represents the reference model in EFFIS (European Forest Fire Information System). RISICO can be considered as an evolution and simplification of the FWI index, properly adapted for the Mediterranean environment. RISICO considers vegetation cover and topography as additional input to the system, considering different contributions to the potential fire behaviour due to different vegetation cover, slope and aspect. This allows taking into account different structure of the fuel available from the ground to the crown including important aspect related with the process of fire spread beyond the weather. The aim of this work is to describe the RISICO model and to perform a performance analysis of the overall system, also by comparing it to the Canadian FWI. The performances of the two models are evaluated on the basis of the Burned Area (BA) observed in Italy in the period 2007-2013, provided by National Civil Protection Department. The Relative Operating Characteristic (ROC) analysis is used to evaluate and compare the performances of the two models. The results of the analysis show that both the systems provide skilful forecast of the wildland fire risk distribution over the Italian territory. However, the performances of RISICO are always better than FWI concerning the capabilities of correctly identifying areas with higher or lower risk significantly reducing the number of false alert with respect to FWI, making it more reliable to the Mediterranean environment.

  12. Ultrastructural and Molecular Characterisation of an Heterosporis-Like Microsporidian in Australian Sea Snakes (Hydrophiinae).

    PubMed

    Gillett, Amber K; Ploeg, Richard; O'Donoghue, Peter J; Chapman, Phoebe A; Webb, Richard I; Flint, Mark; Mills, Paul C

    2016-01-01

    Four sea snakes (two Hydrophis major, one Hydrophis platurus, one Hydrophis elegans) were found washed ashore on different beaches in the Sunshine Coast region and Fraser Island in Queensland, Australia between 2007-2013. Each snake had multiple granulomas and locally extensive regions of pallor evident in the hypaxial and intercostal musculature along the body. Lesions in two individuals were also associated with vertebral and rib fractures. Histological examination revealed granulomas scattered throughout skeletal muscle, subcutaneous adipose tissue and fractured bone. These were composed of dense aggregates of microsporidian spores surrounded by a mantle of macrophages. Sequences (ssrRNA) were obtained from lesions in three sea snakes and all revealed 99% similarity with Heterosporis anguillarum from the Japanese eel (Anguillarum japonica). However, ultrastructural characteristics of the organism were not consistent with those of previous descriptions. Electron microscopic examination of skeletal muscle revealed large cysts (not xenomas) bound by walls of fibrillar material (Heterosporis-like sporophorocyst walls were not detected). The cysts contained numerous mature microsporidian spores arranged in small clusters, sometimes apparently within sporophorous vesicles. The microspores were monomorphic, oval and measured 2.5-3.0 μm by 1.6-1.8 μm. They contained isofilar polar filaments with 11 (infrequently 9-12) coils arranged in two ranks. This is the first published report of a microsporidian infection in hydrophiid sea snakes. This discovery shows microsporidia with molecular affinities to Heterosporis anguillarum but ultrastructural characters most consistent with the genus Pleistophora (but no hitherto described species). Further studies are required to determine whether the microsporidian presented here belongs to the genus Heterosporis, or to a polymorphic species group as suggested by the recognition of a robust Pleistophora/Heterosporis clade by

  13. Modeling organohalide perovskites for photovoltaic applications: From materials to interfaces

    NASA Astrophysics Data System (ADS)

    de Angelis, Filippo

    2015-03-01

    The field of hybrid/organic photovoltaics has been revolutionized in 2012 by the first reports of solid-state solar cells based on organohalide perovskites, now topping at 20% efficiency. First-principles modeling has been widely applied to the dye-sensitized solar cells field, and more recently to perovskite-based solar cells. The computational design and screening of new materials has played a major role in advancing the DSCs field. Suitable modeling strategies may also offer a view of the crucial heterointerfaces ruling the device operational mechanism. I will illustrate how simulation tools can be employed in the emerging field of perovskite solar cells. The performance of the proposed simulation toolbox along with the fundamental modeling strategies are presented using selected examples of relevant materials and interfaces. The main issue with hybrid perovskite modeling is to be able to accurately describe their structural, electronic and optical features. These materials show a degree of short range disorder, due to the presence of mobile organic cations embedded within the inorganic matrix, requiring to average their properties over a molecular dynamics trajectory. Due to the presence of heavy atoms (e.g. Sn and Pb) their electronic structure must take into account spin-orbit coupling (SOC) in an effective way, possibly including GW corrections. The proposed SOC-GW method constitutes the basis for tuning the materials electronic and optical properties, rationalizing experimental trends. Modeling charge generation in perovskite-sensitized TiO2 interfaces is then approached based on a SOC-DFT scheme, describing alignment of energy levels in a qualitatively correct fashion. The role of interfacial chemistry on the device performance is finally discussed. The research leading to these results has received funding from the European Union Seventh Framework Programme [FP7/2007 2013] under Grant Agreement No. 604032 of the MESO project.

  14. Acquired Color Vision Defects and Hexane Exposure: A Study of San Francisco Bay Area Automotive Mechanics.

    PubMed

    Beckman, Stella; Eisen, Ellen A; Bates, Michael N; Liu, Sa; Haegerstrom-Portnoy, Gunilla; Hammond, S Katharine

    2016-06-01

    Occupational exposure to solvents, including n-hexane, has been associated with acquired color vision defects. Blue-yellow defects are most common and may be due to neurotoxicity or retinal damage. Acetone may potentiate the neurotoxicity of n-hexane. We present results on nonhexane solvent and hexane exposure and color vision from a cross-sectional study of 835 automotive repair workers in the San Francisco Bay Area, California (2007-2013). Cumulative exposure was estimated from self-reported work history, and color vision was assessed using the Lanthony desaturated D-15 panel test. Log-binomial regression was used to estimate prevalence ratios for color vision defects. Acquired color vision defects were present in 29% of participants, of which 70% were blue-yellow. Elevated prevalence ratios were found for nonhexane solvent exposure, with a maximum of 1.31 (95% confidence interval (CI): 0.86, 2.00) for blue-yellow. Among participants aged ≤50 years, the prevalence ratio for blue-yellow defects was 2.17 (95% CI: 1.03, 4.56) in the highest quartile of nonhexane solvent exposure and 1.62 (95% CI: 0.97, 2.72) in the highest category of exposure to hexane with acetone coexposure. Cumulative exposures to hexane and nonhexane solvents in the highest exposure categories were associated with elevated prevalence ratios for color vision defects in younger participants. © The Author 2016. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  15. Long term trends of CCN concentration in Arctic region at Zeppelin station, Ny-Ålesund, Svalbard

    NASA Astrophysics Data System (ADS)

    Jung, C. H.; Yoon, Y. J.; Kang, H. J.; Gim, Y. T.; Lee, B. Y.; Ström, J.; Krejci, R.; Tunved, P.

    2015-12-01

    The Arctic is a challenging region when assessing aerosol impacts due to their large variations in concentration, and varying chemical, physical and optical properties. In the climate effects of atmosphere aerosol indirect force, cloud condensation nuclei (CCN) play an important role because particles acting as they can grow to cloud droplets by condensation of water vapor, affecting cloud properties in various ways. For example, the increased CCN concentrations lead to the production of more numerous and smaller cloud drops, which can result in optically thicker clouds that tend to reflect more incoming solar radiation back to space (Twomey, 1977). Thus, investigating the physical process of the CCN aerosol that controls cloud droplet formation is important in understanding the radiative transfer and climate effect. In addition, there are still large variabilities in Arctic CCN number concentrations remaining. These variabilities are mainly due to the result of varying aerosol sources and chemical composition (Browse et al., 2012). Especially, the analysis on the long term trends as well as seasonality of CCN and relation with aerosols are very rare and need to be investigated. In this study, CCN concentration data collected at the Zeppelin observatory located on the top of Mt. Zeppelin, Svalbard (78° 54' N, 11° 53' E) are analyzed during 2007-2013. The seasonal and yearly trends of CCN in the Arctic region during the long periods are presented. The obtained results are compared with other instrumental data such as aerosol size distribution and total number concentration. ReferenceBrowse, J., Carslaw, K. S., Arnold, S. R., Pringle, K., and Boucher, O, 2012, The scavenging processes controlling the seasonal cycle in Arctic sulphate and black carbon aerosol, Atmos. Chem. Phys., 12, 6775-6798. Twomey, S., 1977: Atmospheric Aerosols. Elsevier.

  16. Towards an Integrated Geomagnetic Polarity Reversal Timescale for the Pleistocene

    NASA Astrophysics Data System (ADS)

    Rivera, T. A.; Storey, M.; Kuiper, K.; Palike, H.

    2011-12-01

    The development of the geomagnetic polarity timescale (GPTS) in the mid 20th century led to the greater understanding of seafloor spreading and plate tectonics (Heirtzler et al., 1968). Over 40 years later, the GPTS continues to be refined, particularly in terms of integrating multiple dating techniques to improve precision of such events, or to resolve the duration of geomagnetic transitions. Recent advancements in integrating astronomical and 40Ar/39Ar dating techniques, and improving upon the precision of neutron fluence monitors, necessitate re-evaluation of the accuracy and precision of various geologic events. Here, we review the ages of three Pleistocene geomagnetic polarity reversals: the Matuyama-Brunhes (ca. 0.78 Ma), the Cobb Mountain (ca. 1.2 Ma), and the Reunion (ca. 2.1 Ma) events. High-precision astronomically calibrated 40Ar/39Ar ages have been obtained via a Noblesse multi-collector noble gas mass spectrometer on volcanic and other datable materials related to each event. The ages were derived by single- or multi-crystal total fusion and/or step heating experiments, using the astronomically calibrated Fish Canyon sanidine and/or the astronomically tuned A1 sanidine as monitor minerals. Each of these ages is then compared to independent astronomical ages for the events in order to define tie-points for constructing a Pleistocene a multi-chronometer GPTS. Although only three reversals are addressed here, the methodology applied shows promise to refining short-lived excursions to enable further understanding of the wavering magnetic field. The research leading to these results has received funding from the European Community's Seventh Framework Programme [FP7/2007-2013] under grant agreement no. 215458.

  17. Seasonal variations of temperature-related mortality burden from cardiovascular disease and myocardial infarction in China.

    PubMed

    Yang, Jun; Zhou, Maigeng; Ou, Chun-Quan; Yin, Peng; Li, Mengmeng; Tong, Shilu; Gasparrini, Antonio; Liu, Xiaobo; Li, Jing; Cao, Lina; Wu, Haixia; Liu, Qiyong

    2017-05-01

    Incidence rate of cardiovascular disease (CVD) has significant seasonal trend, being higher in winter. However, the extent to which the seasonal variation of CVD deaths was caused by temperature remains unclear. We obtained daily data on temperature and CVD and myocardial infarction (MI) mortality from nine Chinese mega-cities during 2007-2013. Distributed lag non-linear models were applied to assess the city-specific temperature-related daily excess deaths across lag 0-21 days, using the minimum-mortality temperature as reference. Then, estimates of excess deaths in four seasons were separately aggregated from the daily series, and its ratio to the corresponding total deaths produced seasonal attributable fraction (AF). In total, 1,079,622 CVD and 201,897 MI deaths were recorded in the nine Chinese cities. Significant and non-linear associations between temperature and mortality were observed, with a total of 195,516 CVD and 50,658 MI deaths attributable to non-optimum temperatures. 103,439 (95% empirical CI: 54,475-141,537) CVD and 24,613 (5891-36,279) MI deaths related to non-optimum temperature occurred in winter, compared with 15,923 (1436-28,853) and 4946 (-325-9016) in summer. Temperature-related AFs were higher among MI than CVD, with AFs of 42% (9-62%) and 35% (19-48%) in winter, and 13% (-1-23%) and 8% (1-14%) in summer, respectively. This study may have important implications for developing effective targeted intervention measures on CVD events. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Changing climate and the altitudinal range of avian malaria in the Hawaiian Islands - an ongoing conservation crisis on the island of Kaua'i.

    PubMed

    Atkinson, Carter T; Utzurrum, Ruth B; Lapointe, Dennis A; Camp, Richard J; Crampton, Lisa H; Foster, Jeffrey T; Giambelluca, Thomas W

    2014-08-01

    Transmission of avian malaria in the Hawaiian Islands varies across altitudinal gradients and is greatest at elevations below 1500 m where both temperature and moisture are favorable for the sole mosquito vector, Culex quinquefasciatus, and extrinsic sporogonic development of the parasite, Plasmodium relictum. Potential consequences of global warming on this system have been recognized for over a decade with concerns that increases in mean temperatures could lead to expansion of malaria into habitats where cool temperatures currently limit transmission to highly susceptible endemic forest birds. Recent declines in two endangered species on the island of Kaua'i, the 'Akikiki (Oreomystis bairdi) and 'Akeke'e (Loxops caeruleirostris), and retreat of more common native honeycreepers to the last remaining high elevation habitat on the Alaka'i Plateau suggest that predicted changes in disease transmission may be occurring. We compared prevalence of malarial infections in forest birds that were sampled at three locations on the Plateau during 1994-1997 and again during 2007-2013, and also evaluated changes in the occurrence of mosquito larvae in available aquatic habitats during the same time periods. Prevalence of infection increased significantly at the lower (1100 m, 10.3% to 28.2%), middle (1250 m, 8.4% to 12.2%), and upper ends of the Plateau (1350 m, 2.0% to 19.3%). A concurrent increase in detections of Culex larvae in aquatic habitats associated with stream margins indicates that populations of the vector are also increasing. These increases are at least in part due to local transmission because overall prevalence in Kaua'i 'Elepaio (Chasiempis sclateri), a sedentary native species, has increased from 17.2% to 27.0%. Increasing mean air temperatures, declining precipitation, and changes in streamflow that have taken place over the past 20 years are creating environmental conditions throughout major portions of the Alaka'i Plateau that support increased

  19. Dynamics of thin-skinned fold and thrust belts with a tilted detachment

    NASA Astrophysics Data System (ADS)

    Fernandez, Naiara; Kaus, Boris J. P.; Epard, Jean-Luc

    2014-05-01

    The formation of the Jura fold and thrust belt is linked to the Alpine orogeny. However, it is still a matter of debate why the Jura was formed tens of kilometres far away from the active deformation front while the Molasse basin that lies in between remained mostly undeformed. Progressive thickening of the Molasse basin due to its infill with sediments, and the existence of a tilted potential detachment level at the Triassic evaporitic units, have been pushed forward as the main causes for the detachment of the Molasse basin and the consequent jump of the deformation front from the Alpine front to the position of the Jura at around 22 Ma or later (e.g Willett and Schlunegger, 2010). In order to better understand the dynamics of a thin-skinned fold and thrust belt with a tilted detachment we have performed systematic forward numerical simulations with the 2D thermo-mechanical finite element code MILAMIN_VEP. The modelled setup consists of a tilted detachment, overlain by a sedimentary cover of constant thickness and a wedge shaped basin infill that makes the initial surface slope of the system to be zero. In this study we have tested the importance of the following factors in the dynamics of such a fold and thrust belt evolution: 1) the applied boundary conditions 2) the angle of a uniformly tilted detachment 3) the end displacement of a curved detachment with a flexural foreland basin profile. The implications of the studied factors are discussed for the case of the Jura-Molasse system. Acknowledgements Funding was provided by the European Research Council under the European Community's Seventh Framework program (FP7/2007-2013) ERC Grant agreement #258830. References Willett, S.D. and Schlunegger, F. 2010, The last phase of deposition in the Swiss Molasse Basin: from foredeep to negative-alpha basin. Basin Research 22, 623-639, doi: 10.1111/j.1365-2117.2009.00435.x

  20. A Time Series Model for Assessing the Trend and Forecasting the Road Traffic Accident Mortality.

    PubMed

    Yousefzadeh-Chabok, Shahrokh; Ranjbar-Taklimie, Fatemeh; Malekpouri, Reza; Razzaghi, Alireza

    2016-09-01

    Road traffic accident (RTA) is one of the main causes of trauma and known as a growing public health concern worldwide, especially in developing countries. Assessing the trend of fatalities in the past years and forecasting it enables us to make the appropriate planning for prevention and control. This study aimed to assess the trend of RTAs and forecast it in the next years by using time series modeling. In this historical analytical study, the RTA mortalities in Zanjan Province, Iran, were evaluated during 2007 - 2013. The time series analyses including Box-Jenkins models were used to assess the trend of accident fatalities in previous years and forecast it for the next 4 years. The mean age of the victims was 37.22 years (SD = 20.01). From a total of 2571 deaths, 77.5% (n = 1992) were males and 22.5% (n = 579) were females. The study models showed a descending trend of fatalities in the study years. The SARIMA (1, 1, 3) (0, 1, 0) 12 model was recognized as a best fit model in forecasting the trend of fatalities. Forecasting model also showed a descending trend of traffic accident mortalities in the next 4 years. There was a decreasing trend in the study and the future years. It seems that implementation of some interventions in the recent decade has had a positive effect on the decline of RTA fatalities. Nevertheless, there is still a need to pay more attention in order to prevent the occurrence and the mortalities related to traffic accidents.

  1. Rising methane: post-2007 growth, geographic loci, timings and isotopic shift

    NASA Astrophysics Data System (ADS)

    Nisbet, Euan G.; Manning, Martin R.; Dlugokencky, Ed; Lowry, David; Fisher, Rebecca E.; Brownlow, Rebecca

    2017-04-01

    Atmospheric methane is rising rapidly again, after a period of stability [1]. NOAA report a global growth rate from 2007-2013 of 5.7±1.2 ppb yr-1, followed by extreme growth of 12.6±0.5 ppb in 2014 and 10.0±0.7 ppb in 2015. Growth has been accompanied by a shift in δ13C(CH4) (a measure of the 13C/12C isotope ratio in methane) to significantly more negative values since 2007. This isotopic shift has been observed in independently calibrated NOAA, Royal Holloway and NIWA-New Zealand measurements: thus the negative trend is real, global, and not a calibration artifact. Fossil fuel methane emissions, which are mostly more positive than atmospheric values, are not driving the rise in methane. Instead, the geographic loci of post-2007 growth, and the timings of the methane rise and isotopic shift suggest growth was dominated by significant increases in biogenic methane emissions, particularly in the tropics and Southern Hemisphere: for example in years with heavy rainfall under the Inter-Tropical Convergence, from wetlands and increased agricultural sources such as ruminants and rice paddies. Changes in the removal rate of methane by the OH radical or other sinks may also have occurred but do not appear fully to explain short term variations in methane isotopes. All these drivers of rising methane - wetlands, ruminants, changing sinks - may reflect underlying decade-long trends in tropical climate: methane may thus be an important climate-change signal. 1. Nisbet, E.G. et al. (2016) Rising atmospheric methane: 2007-2014 growth and isotopic shift, Global Biogeochem. Cycles, 30, doi:10.1002/ 2016GB005406.

  2. Performance of the operational high-resolution numerical weather predictions of the Daphne project

    NASA Astrophysics Data System (ADS)

    Tegoulias, Ioannis; Pytharoulis, Ioannis; Karacostas, Theodore; Kartsios, Stergios; Kotsopoulos, Stelios; Bampzelis, Dimitrios

    2015-04-01

    and Entrepreneurship" and Regions in Transition (OPC II, NSRF 2007-2013)

  3. The Positive Outcome of MRI-Guided Vacuum Assisted Core Needle Breast Biopsies Is Not Influenced by a Prior Negative Targeted Second-Look Ultrasound.

    PubMed

    Ferré, Romuald; AlSharif, Shaza; Aldis, Ann; Mesurolle, Benoît G

    2017-08-21

    The study sought to investigate the outcome of breast magnetic resonance-guided biopsies as a function of the indication for magnetic resonance imaging (MRI), the MRI features of the lesions, and the performance or not of a targeted second-look ultrasound (SLUS) prior breast MRI-guided biopsy. We identified 158 women with MRI-detected breast lesions scheduled for MRI-guided biopsy (2007-2013). Patient demographics, performance of targeted SLUS, imaging characteristics, and subsequent pathology results were reviewed. Three biopsies were deferred, and 155 lesions were biopsied under MRI guidance (155 women; median age 55.14 years; range 27-80 years). Ninety-eight women underwent a SLUS prior to the MRI-guided biopsy (63%). Of the 155 biopsied lesions, 23 (15%) were malignant, 106 (68%) were benign, and 26 (17%) were high risk. Four of 15 surgically excised high-risk lesions were upgraded to malignancy (27%). Most of the biopsied lesions corresponded to non-mass-like enhancement (81%, 126 of 155) and most of the biopsies (52%, 81 of 155) were performed in a screening context. No demographic or MRI features were associated with malignancy. No differences were noted between the 2 subgroups (prior SLUS vs no prior SLUS) except for the presence of a synchronous carcinoma associated with a likelihood of targeted SLUS before MRI-guided biopsy (P = .001). A negative SLUS does not influence the pathology outcome of a suspicious lesion biopsied under MR guidance. Copyright © 2017 Canadian Association of Radiologists. Published by Elsevier Inc. All rights reserved.

  4. [Gender inequalities in research in public health and epidemiology in Spain (2007-2014)].

    PubMed

    García-Calvente, María Del Mar; Ruiz-Cantero, María Teresa; Del Río-Lozano, María; Borrell, Carme; López-Sancho, M Pilar

    2015-01-01

    To analyse gender inequalities in research on public health and epidemiology in Spain for the period 2007-2014. A descriptive study was conducted by sex of leadership positions in the Centre for Biomedical Research Network (CIBER), especially in the subject area of epidemiology and public health (CIBERESP) in 2014; scientific societies of public health (SESPAS) and epidemiology (SEE) 2009-2014; research projects requested (13,320) and financed (4,699), and monetary amounts of calls for Strategic Action in Health (AES), 2007-2013. Women were clearly under-represented in positions of leadership and in research excellence in public health (CIBER), with a predominance of men in decision-making positions. Although research projects led by women in AES increased slightly between 2007 and 2013, among proposed projects this figure was less than 50%, with the exception of the public health commission. The gender gap was even greater in funded projects. Projects led by men were more likely to be funded, representing 29% in public health. There was also a persistence of horizontal gender segregation in positions of scientific recognition in the SESPAS and SEE Congresses. The overrepresentation of male leaders in public health research in Spain can be understood as an indicator and a consequence of androcentrism in scientific societies and professional groups. This sexist situation threatens the existence of innovative products and services from a gender perspective that respond to the needs and demands of society as a whole. More women are needed in research incorporating this perspective. Copyright © 2015 SESPAS. Published by Elsevier Espana. All rights reserved.

  5. Irradiation effect on deuterium behaviour in low-dose HFIR neutron-irradiated tungsten

    SciTech Connect

    Shimada, Masashi; Cao, G.; Otsuka, T.; Hara, M.; Kobayashi, M.; Oya, Y.; Hatano, Y.

    2014-12-01

    Tungsten samples were irradiated by neutrons in the High Flux Isotope Reactor, Oak Ridge National Laboratory at reactor coolant temperatures of 50-70°C to low displacement damage of 0.025 and 0.3 dpa under the framework of the US-Japan TITAN program (2007-2013). After cooling down, the HFIR neutron-irradiated tungsten samples were exposed to deuterium plasmas in the Tritium Plasma Experiment, Idaho National Laboratory at 100, 200 and 500 °C twice at the ion fluence of 5×10²⁵ m⁻² to reach a total ion fluence of 1×10²⁶ m⁻² in order to investigate the near surface deuterium retention and saturation via nuclear reaction analysis. Final thermal desorption spectroscopy was performed to elucidate irradiation effect on total deuterium retention. Nuclear reaction analysis results showed that the maximum near surface (<5 µm depth) deuterium concentration increased from 0.5 at % D/W in 0.025 dpa samples to 0.8 at. % D/W in 0.3 dpa samples. The large discrepancy between the total retention via thermal desorption spectroscopy and the near surface retention via nuclear reaction analysis indicated the deuterium was migrated and trapped in bulk (at least 50 µm depth for 0.025 dpa and 35 µm depth for 0.025 dpa) at 500 °C case even in the relatively low ion fluence of 10²⁶ m⁻².

  6. A dynamical study of the multiple system 17 Cygni ABFG

    NASA Astrophysics Data System (ADS)

    Romanenko, L. G.

    2017-03-01

    Adynamical study of the relative motions of the components of the inner pairs AB (ADS 12913) and FG (ADS 12889) of the quadruple heirarchical system 17 Cygni (WDS 19464+3344) is presented, as well as analysis of themotions of the outer pair AB-FG. The study is based on CCD observations obtained on the 26-inch refractor of the Pulkovo Observatory (2003-2013), position observations from the WDS catalog, Hipparcos parallaxes, and radial velocities of the components from literature data. A family of orbits for 17 Cyg AB is obtained for the first time, and has a most probable period of 6200 yrs. The apparent motion parameters (AMP) method is used, since the entire visible arc of the orbit over 1832-2013 is only 4°. The AMP method is also used to calculate the orbit of the 17 Cyg FG pair, which has a period of 238 yrs, yielding results in good agreement with the orbits derived in other studies. The ephemerides of the obtained AMP orbits, the position data for the AF pair from the WDS catalog (11 positions during 1893-2002), and Pulkovo CCD observations for 2007-2013 are used to calculate the apparent motion parameters of AB-FG outer pair, as well as a family of close-to-parabolic orbits with periods of 3.7 million years ormore. All the orbits (for both the inner and the outer pairs) are steeply inclined to theGalactic plane. Monte Carlo simulations are used to compute the probability that the outer pair is gravitationally bound, which is 47%. The similarity of the proper motions and radial velocities of all the components provides evidence that they all belong to a single stellar stream. Data from the CNS3 catalog are used to compose a list of candidate members of this stream.

  7. Urban development change detection based on Multi-Temporal Satellite Images as a fast tracking approach--a case study of Ahwaz County, southwestern Iran.

    PubMed

    Malmir, Maryam; Zarkesh, Mir Masoud Kheirkhah; Monavari, Seyed Masoud; Jozi, Seyed Ali; Sharifi, Esmail

    2015-03-01

    Rapid land-use/land-cover changes in suburbs of metropolitan cities of Iran have recently caused serious environmental damages. Detection of these changes can be a very important step in urban planning and optimal use of natural resources. Accordingly, the present study was carried out to track land-use/land-cover (LULC) changes of Ahwaz County in southwestern Iran using remote sensing techniques over a period of 26 years, from 1987 to 2013. For this, ISODATA algorithm and Maximum Likelihood were initially used for unsupervised and supervised classifications of the satellite images. The accuracy of the LULC maps was checked by the Kappa Coefficient and the Overall Accuracy methods. As the final step, the LULC changes were detected using the cross-tabulation technique. The obtained results indicated that urban and agricultural areas have been increased about 57.5 and 84.5 %, respectively, from 1987 to 2013. Further, the area of poorly vegetated regions, in the same period, has been decreased to approximately 36 %. The largest land conversion area belongs to the poorly vegetated regions, which have been declined to about 10,371 and 1,334 ha during 1987-2007 and 2007-2013, respectively. Approximately 1,670 and 382 ha of the agricultural lands have also been changed to built-up areas by about 1,670 and 382 ha during the same periods. As a result, it was found that the northwest, southwest, and south of the county were highly subjected to urban development. This would be of great importance for urban planning decision-making faced by the planners of the city in the present and future.

  8. El Niño Southern Oscillation influences the abundance and movements of a marine top predator in coastal waters.

    PubMed

    Sprogis, Kate R; Christiansen, Fredrik; Wandres, Moritz; Bejder, Lars

    2017-10-08

    Large-scale climate modes such as El Niño Southern Oscillation (ENSO) influence population dynamics in many species, including marine top predators. However, few quantitative studies have investigated the influence of large-scale variability on resident marine top predator populations. We examined the effect of climate variability on the abundance and temporary emigration of a resident bottlenose dolphin (Tursiops aduncus) population off Bunbury, Western Australia (WA). This population has been studied intensively over six consecutive years (2007-2013), yielding a robust dataset that captures seasonal variations in both abundance and movement patterns. In WA, ENSO affects the strength of the Leeuwin Current (LC), the dominant oceanographic feature in the region. The strength and variability of the LC affects marine ecosystems and distribution of top predator prey. We investigated the relationship between dolphin abundance and ENSO, Southern Annular Mode, austral season, rainfall, sea surface salinity and sea surface temperature (SST). Linear models indicated that dolphin abundance was significantly affected by ENSO, and that the magnitude of the effect was dependent upon season. Dolphin abundance was lowest during winter 2009, when dolphins had high temporary emigration rates out of the study area. This coincided with the single El Niño event that occurred throughout the study period. Coupled with this event, there was a negative anomaly in SST and an above average rainfall. These conditions may have affected the distribution of dolphin prey, resulting in the temporary emigration of dolphins out of the study area in search of adequate prey. This study demonstrated the local effects of large-scale climatic variations on the short-term response of a resident, coastal delphinid species. With a projected global increase in frequency and intensity of extreme climatic events, resident marine top predators may not only have to contend with increasing coastal

  9. Association of Education and Smoking Status on Risk of Diabetes Mellitus: A Population-Based Nationwide Cross-Sectional Study.

    PubMed

    Kim, Jin-Hyeong; Noh, Juhwan; Choi, Jae-Woo; Park, Eun-Cheol

    2017-06-19

    Background: Exposure to smoke, including environmental tobacco smoke (ETS), is a well-known risk factor for diabetes. Low socioeconomic status, especially lack of education, is also a risk factor for diabetes. Therefore, we assessed the association of demographic, socioeconomic, clinical, and behavior risk factor-related variables and smoking status, including ETS exposure, with the prevalence of diabetes. Methods: Data were from the 2007-2013 Korea National Health and Nutritional Evaluation Survey (KNHANES). Multivariable logistic regression examined associations between various lifestyle and health factors and the prevalence of diabetes while controlling for potential confounding variables. Subgroup analysis was performed according to smoking status to determine factors associated with diabetes. Results: Of 19,303 individuals analyzed, 1325 (11.4%) had diabetes. Greater average age, male sex, lower educational level, unemployment, and coexisting health problems were significantly associated with diabetes. Individuals with only elementary, middle, or high school level education had significantly greater odds ratios (p < 0.05) compared to college graduates; smokers and nonsmokers exposed to ETS had significantly greater OR (p < 0.05) than nonsmokers unexposed to ETS. Subgroup analysis of diabetics according to smoking status revealed significant associations (p < 0.05) for diabetic nonsmokers exposed to ETS with female sex, single status, elementary level education, urban residence, National Health Insurance (NHI), hypertension, a lack of alcohol intake, and a lack of moderate physical activity. For diabetic smokers, there were significant associations (p < 0.05) with elementary education, urban residence, a lack of moderate physical activity, a lack of alcohol intake, and NHI. Conclusions: The results suggested that smoking status, as well as ETS exposure, was associated with a higher prevalence of diabetes, especially in populations with less education. Thus, we

  10. Seasonal and Regional Variability in North Pacific Upper-Ocean Turbulence

    NASA Astrophysics Data System (ADS)

    Najjar, R.; Creedon, R.; Cronin, M. F.

    2016-02-01

    Turbulent diffusion at marine mixed layer base (MLB) plays a fundamental role in the transport of energy between the upper and abyssal ocean. Recent investigations of North Pacific mooring data at Ocean Climate Stations (OCS) Papa (50.1N,144.9W) and KEO (32.3N,144.6E) suggest seasonal and regional variability in thermal diffusivity (κT). In this investigation, it is hypothesized that these observed differences in κT are directly associated with synoptic variability in net surface heat flux (Q0), surface wind stress (τ), mixed layer depth (h), and density stratification at MLB (∂zσ|-h). To test this hypothesis, daily-averaged time series of κT are regressed against those of Q0, τ, h, and ∂zσ|-h at both Papa and KEO over a six year time period (2007-2013). Seasonality of each time series is removed before regression to capture synoptic variability of each variable. Preliminary results of the regression analysis suggest statistically significant correlations between κT and all forcing parameters at both mooring sites. These correlations have well-determined orders of magnitude and signs consistent with the hypothesis. As a result, differences in κT between Papa and KEO may be recast in terms of differences in their correlation coefficients. In order to continue investigation of these parameters and their effects on mean seasonal differences between the two regions, these results will be compared with turbulence predicted by the K-Profile Parameterization ocean turbulence model.

  11. Intussusception Rates Before and After the Introduction of Rotavirus Vaccine.

    PubMed

    Tate, Jacqueline E; Yen, Catherine; Steiner, Claudia A; Cortese, Margaret M; Parashar, Umesh D

    2016-09-01

    Recent US studies have identified a small increased risk of intussusception after rotavirus vaccination, mainly after the first dose. We examined trends in intussusception hospitalizations before (2000-2005) and after (2007-2013) rotavirus vaccine introduction to assess whether this observed temporal risk translates into more hospitalized cases at the population level. Intussusception hospitalizations in children <12 months of age were abstracted from the State Inpatient Database maintained by the Healthcare Cost and Utilization Project for 26 states that provided data from 2000 to 2013. Rates were calculated using bridged-race postcensal population estimates. Trends were analyzed by age groups (6-14 weeks, 15-24 weeks, and 25-34 weeks) based on the recommended ages for vaccine administration as well as 8-11 weeks when the majority of first doses are given. Rate ratios were calculated by using Poisson regression. No consistent change in intussusception hospitalization rates was observed among all children <12 months of age and among children 15 to 24 weeks and 25 to 34 weeks of age. The intussusception hospitalization rate for children aged 8 to 11 weeks was significantly elevated by 46% to 101% (range: 16.7-22.9 per 100 000) in all postvaccine years except 2011 and 2013 compared with the prevaccine baseline (11.7 per 100 000). The increase in the intussusception hospitalization rate in children 8 to 11 weeks when the majority of first doses of vaccine are given is consistent with recent US postlicensure studies. Given the magnitude of declines in rotavirus disease compared with this small increase in intussusception, the benefits of rotavirus vaccination outweigh the increase risk of intussusception. Copyright © 2016 by the American Academy of Pediatrics.

  12. Paperbark and pinard: A historical account of maternity care in one remote Australian Aboriginal town.

    PubMed

    Ireland, Sarah; Belton, Suzanne; McGrath, Ann; Saggers, Sherry; Narjic, Concepta Wulili

    2015-12-01

    Maternity care in remote areas of the Australian Northern Territory is restricted to antenatal and postnatal care only, with women routinely evacuated to give birth in hospital. Using one remote Aboriginal community as a case study, our aim with this research was to document and explore the major changes to the provision of remote maternity care over the period spanning pre-European colonisation to 1996. Our research methods included historical ethnographic fieldwork (2007-2013); interviews with Aboriginal women, Aboriginal health workers, religious and non-religious non-Aboriginal health workers and past residents; and archival review of historical documents. We identified four distinct eras of maternity care. Maternity care staffed by nuns who were trained in nursing and midwifery serviced childbirth in the local community. Support for community childbirth was incrementally withdrawn over a period, until the government eventually assumed responsibility for all health care. The introduction of Western maternity care colonised Aboriginal birth practices and midwifery practice. Historical population statistics suggest that access to local Western maternity care may have contributed to a significant population increase. Despite population growth and higher demand for maternity services, local maternity services declined significantly. The rationale for removing childbirth services from the community was never explicitly addressed in any known written policy directive. Declining maternity services led to the de-skilling of many Aboriginal health workers and the significant community loss of future career pathways for Aboriginal midwives. This has contributed to the current status quo, with very few female Aboriginal health workers actively providing remote maternity care. Copyright © 2015 Australian College of Midwives. Published by Elsevier Ltd. All rights reserved.

  13. Arterial Injuries Associated with Blunt Fractures in the Lower Extremity.

    PubMed

    Coleman, Jamie J; Tavoosi, Saharnaz; Zarzaur, Ben L; Brewer, Brian L; Rozycki, Grace S; Feliciano, David V

    2016-09-01

    Problems related to the combination of an arterial injury and a blunt fracture in the lower extremity are well known-delayed diagnosis, damaged soft tissue, and high amputation rate. The actual incidence of this injury pattern is, however, unknown. The purposes of this study were to determine the current incidence of named arterial injuries in patients with blunt fractures in the lower extremities and assess potential associated risk factors. This was a 7-year (2007-2013) retrospective review of patients ≥18 years with blunt lower extremity fractures at a Level I trauma center. Fracture location and concomitant arterial injury were determined and patients stratified by age, gender, and injury velocity. Low injury velocity was defined as falls or assaults, whereas an injury secondary to a motorized vehicle was defined as high velocity. A total of 4413 patients (mean age 52.2 years, 54.3% male, mean Injury Severity Score 13.1) were identified. Forty-six patients (1.04%) had arterial injuries (20.4% common femoral, 8.2% superficial femoral, 44.9% popliteal, and 26.5% shank). After stratifying by age and injury velocity, younger age was associated with a significantly higher rate of vascular injury. For high-velocity injuries, there was no difference based on age. In conclusion, the prevalence of arterial injury after blunt lower extremity fractures is 1.04 per cent in our study. A significant paradoxical relationship exists between age and associated arterial injuries in patients with low-velocity injuries. If these data are confirmed in future studies, a low index of suspicion in patients >55 years after falls is appropriate.

  14. An investigation of antimicrobial usage patterns by small animal veterinarians in South Africa.

    PubMed

    Chipangura, John K; Eagar, Hayley; Kgoete, Marcia; Abernethy, Darrell; Naidoo, Vinny

    2017-01-01

    At present very little information is available on antimicrobial use patterns in small animal veterinary practice in South Africa. The aim of this study was firstly to provide some indication of antimicrobial use patterns, and secondly to ascertain if the country's small animal veterinarians make use of prudent use guidelines to optimise their antimicrobial use in order to minimise the development of antimicrobial resistance. In order to understand use patterns, a questionnaire was circulated to registered South African veterinarians, whose responses were evaluated by descriptive statistics. The prevalence of antimicrobial resistance was evaluated for dogs from samples submitted for culture and susceptibility testing for the period 2007-2013 from the only faculty of Veterinary Science in the country. The resistance data was organized into contingency tables and yearly trends in resistance evaluated by means of a chi-square. The use of antimicrobials from the survey were compared to the laboratory result to ascertain the degree of prudent use of the antimicrobials in small animal practice in a developing country. The responses from the questionnaire indicated that South African veterinarians predominantly (91.16%) used antimicrobials empirically before resorting to laboratory testing and that antimicrobial compounding and off label use (86.19%) of human registered medication was common practice. A worrying finding was that a large number of clients attempted antimicrobial treatment of their pets prior to seeking veterinary assistance. In terms of monitored resistance, annual prevalence of resistance was above 10% and multiple drug resistance was above 50% for all the isolates. It is concluded that antimicrobial resistant bacteria are present in small companion animal practice in South Africa which requires better implementation of prudent use guidelines. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. Laboratory-scale interaction between CO2-rich brine and limestone and sandstone under supercritical CO2 conditions

    NASA Astrophysics Data System (ADS)

    Garcia-Rios, Maria; Cama, Jordi; Luquot, Linda; Soler, Josep

    2014-05-01

    A test site for a prospective CO2 geological storage is situated in Hontomín (Burgos, northern Spain) with a reservoir rock that is composed of limestone (calcite) and sandstone (66 wt.% calcite, 28 wt.% quartz and 6 wt.% microcline). During and after CO2 injection, the resulting CO2-rich acid brine will likely promote the dissolution of carbonate minerals (calcite) and aluminosilicates (microcline). Since the reservoir Hontomín brine contains sulfate, gypsum (or anhydrite at depth) may precipitate. These coupled dissolution and precipitation reactions may induce changes in porosity and pore structure of the repository rocks. Percolations experiments with mechanically fractured cores (8.6 mm in diameter and 18 mm length) were performed under CO2 supercritical conditions (Pfluid = 150 bar; pCO2 ≡ 90 bar and T = 60 ºC) in order to evaluate and quantify variations in fracture permeability, preferential path formation and fracture volume. The brine sulfate content and the flow rate were varied. Regarding limestone, as the synthetic brines circulated through the fracture, the fracture permeability initially increased slowly, to thereafter increase rapidly. This change was due to a localized dissolution process (wormhole formation) along the core that occurred regardless gypsum precipitation. Nonetheless, the originated fracture volume in the sulfate-rich brine experiments was a factor of two smaller than that in sulfate-free brine experiments. Also, an increase in flow rate from 0.2 to 60 mL/h increased the volume of both dissolved calcite and precipitated gypsum. Regarding sandstone, permeability increased gradually with time. Nonetheless, this increase was not always continuous due to eventual fracture clogging. Formation of wormholes was observed. Acknowledgements This study was financed by CIUDEN (Ciudad de la Energía), the Compostilla OXYCFB300 project and the PANACEA project (European Community's Seventh Framework Programme FP7/2007-2013 under grant

  16. Simultaneous recording of t-tubular electrical activity and Ca2+-release in heart failure

    NASA Astrophysics Data System (ADS)

    Crocini, C.; Coppini, R.; Ferrantini, C.; Yan, P.; Loew, L.; Tesi, C.; Poggesi, C.; Cerbai, E.; Pavone, F. S.; Sacconi, L.

    2014-05-01

    T-tubules (TT) are invaginations of the surface sarcolemma (SS) that mediate the rapid propagation of the action potential (AP) to the cardiomyocyte core. We employed the advantages of an ultrafast random access multi-photon (RAMP) microscope (Sacconi et al., PNAS 2012) with a double staining approach to optically record t-tubular AP and, simultaneously, the corresponding local Ca2+-release in different positions across the cardiomyocytes. Despite a uniform AP between SS and TT at steady-state stimulation, in control cardiomyocytes we observed a non-negligible be variability of local Ca2+-transient amplitude and kinetics. This variability was significantly reduced by applying 0.1μM Isoproterenol, which increases the opening probability of Ca2+-release units. In the rat heart failure model (HF), we previously demonstrated that some tubular elements fail to propagate AP. We found that the tubules unable to propagate AP, displayed a reduced correspondent Ca2+-transient amplitude as well as a slower Ca2+ rise compared to electrically coupled tubules. Moreover variability of Ca2+-transient kinetics were increased in HF. Finally, TT that did not show AP, occasionally exhibited spontaneous depolarizations that were never accompanied by local Ca2+-release in the absence of any pro-arrhythmogenic stimulation. Simultaneous recording of AP and Ca2+-transient allows us to probe the spatio-temporal variability of Ca2+-release, whereas the investigation of Ca2+-transient in HF discloses an unexpected uncoupling between t-tubular depolarization and Ca2+-release in remodeled tubules. This work was funded by the European Union 7th Framework Program (FP7/2007- 2013) under grant agreement n° 284464, 241526, by the Italian Ministry of University and Research (NANOMAX), and by Telethon-Italy (GGP13162).

  17. Collective spin waves in reconfigurable artificial crystals and magnonic meta-materials

    NASA Astrophysics Data System (ADS)

    Grundler, Dirk

    2014-03-01

    Periodically nanopatterned ferromagnets have generated great interest in the research field of magnonics in that they support spin-wave (SW) nanochannels, allow for multi-directional emission of short-wavelength SWs via the grating coupler effect and form artificial crystals for SWs (magnons) in the GHz frequency regime. Allowed SW minibands and forbidden frequency gaps are not just tailored by the geometrical and material parameters, but reflect decisively the periodic order of the nanomagnets' remanent magnetization. Thereby a further degree of freedom is offered for controlling wave phenomena in solids compared to photonics and plasmonics. We investigated such so-called reconfigurable magnonic crystals (MCs) consisting of a one-dimensional (1D) array of permalloy nanostripes that allow one to vary the Brillouin zone boundaries, forbidden frequency gaps and number of SW minibands in one-and-the same device. When excited by a microwave antenna, an unexpected metamaterial property was found in that both reciprocal and nonreciprocal SW excitation occurred depending on the parallel and antiparallel alignment of magnetic moments in neighboring stripes. Such excitation characteristics are not found in natural materials. Switching an individual stripe from parallel to antiparallel magnetization in an otherwise saturated 1D MC modified the transmitted SW amplitude considerably offering SW control on the nanoscale. Combined with the grating coupler effect, periodically nanopatterned ferromagnets are expected to provide interesting building blocks for magnonic applications aiming at transmitting and processing information at microwave frequencies with spin waves. Funding from the European Community's 7th Framework Programme (FP7/2007-2013) under grant No. 228673 MAGNONICS, No. 247556 NoWaPhen, the DFG via GR1640/5-1 (SPP 1538) and the German Excellence Cluster `Nanosystems Initiative Munich (NIM)' is acknowledged.

  18. Nonlinear Behavior of the Geomagnetic Fluctuations Recorded in Different Geomagnetic Latitudes

    NASA Astrophysics Data System (ADS)

    Kovacs, P.; Heilig, B.; Koppan, A.; Vadasz, G.; Echim, M.

    2014-12-01

    The paper concerns with the nonlinear properties of geomagnetic variations recorded in different geomagnetic latitudes, in the years of solar maximum and minimum. For the study, we use the geomagnetic time-series recorded by some of the stations of the EMMA quasi-meridional magnetometer network, established for pulsation study, in September 2001. The stations are located approx. along the magnetic meridian of 100 degree, and the sampling frequency of the series is 1 Hz. It is argued that the geomagnetic field exhibits nonlinear intermittent fluctuations in certain temporal scale range. For quantitatively investigating the scaling ranges and the variation of intermittent properties with latitude and time, we analyse the higher order moments of the time records (probability density function or structure function analyses). The multifractal or self-similar scaling of the fluctuations is investigated via the fitting of the P model to structure function scaling exponents. We also study the power-law behaviour of the power-spectral density functions of the series in order to evaluate the possible inertial frequency (and temporal) range of the geomagnetic field and compare them with the scaling ranges of structure functions. The range where intermittent geomagnetic variation is found falls typically between 100 and 20.000 s, i.e. covers the temporal range of the main phases of geomagnetic storms. It is shown that the intensity of intermittent fluctuations increases from solar minimum to solar maximum. The expected increase in the level of intermittency with the geomagnetic latitude can be evidenced only in the years of solar minimum. The research leading to these results has received funding from the European Community's Seventh Framework Programme ([FP7/2007-2013]) under grant agreement n° 313038/STORM.

  19. Estimating age-specific trends in circulating testosterone and sex hormone-binding globulin in males and females across the lifespan.

    PubMed

    Handelsman, David J; Sikaris, Ken; Ly, Lam P

    2016-05-01

    Age-specific trends of serum testosterone and sex hormone-binding globulin across the full lifespan have not been reported. We deduced age-specific trends in serum testosterone and sex hormone-binding globulin in males and females between ages 10 and 90 from a large sample of consecutive results from a single large pathology laboratory. Coded results of 110,712 consecutive blood samples requesting serum testosterone over seven years (2007-2013) comprising blood testosterone, sex hormone-binding globulin and calculated free testosterone together with gender and age were analysed create smoothed age-specific centiles (2.5%, 5%, 25%, 50%, 75%, 95%, 97.5%) for males and females. These identified the pubertal increases in serum testosterone in males peaking at 20 years of age and remaining stable thereafter until the eighth decade. In females, circulating testosterone peaked in late adolescence and declined gradually over the next two decades but remained stable across menopause and beyond. After early childhood, serum sex hormone-binding globulin declines to a nadir in males at the age of 20 years and remains stable till the sixth decade with a gradual, progressive rise thereafter. In females, the sex hormone-binding globulin nadir is reached earlier with levels rising gradually and progressively with age thereafter and accelerating after the age of 70 years. Females also exhibit a second sex hormone-binding globulin peak during reproductive ages reflected only in upper centiles due to effects of pregnancy and oral contraceptive use in a significant minority of females. This large sample of clinical data provides a comprehensive profile of androgen status across the lifespan from early adolescence to late old age. © The Author(s) 2015.

  20. New multi-beam bathymetric map of the Ionian Sea (Central Mediterranean): Evidence for active sedimentary and morpho-tectonic processes along the Africa-Eurasia plate boundary

    NASA Astrophysics Data System (ADS)

    Gutscher, M. A.; Kopp, H.; Krastel, S.; Bohrmann, G.; Garlan, T.; Zaragosi, S.; Klaucke, I.; Wintersteller, P.; Loubrieu, B.; Le Faou, Y.; San Pedro, L.; Dominguez, S.; Rovere, M.; Mercier De Lepinay, B. F.

    2015-12-01

    A combined dataset of multi-beam bathymetry, based on 5 recent marine geophysical surveys since 2010 as well as a compilation of earlier surveys, now spans the vast majority of the Ionian Sea and the active margin of East Sicily and Calabria. (The new surveys are: R/V Meteor cruise 86, 2010 PI - S. Krastel; MocoSed R/V PourquoiPas 2012 PI - T. Garlan; Circee R/V Suroit 2013 PI - M.-A. Gutscher; R/V Meteor cruise 111, 2014 PI's - H. Kopp, M.-A. Gutscher; R/V Meteor cruise 112, 2014 PI - G. Bohrmann). This new compilation of mostly unpublished bathymetric data is presented as a 2 arc-sec (60m) grid and reveals fine-scale structures on the seafloor in unprecedented detail. These include the deeply incised Malta-Hyblean Escarpment, numerous submarine canyons, broad regions of relatively flat seafloor dominated by fields of sediment waves, the gently undulating anticlinal fold-and-thrust belts of two accretionary wedge complexes related to the Hellenic subduction (W Mediterranean ridge) and to the Calabrian arc. These accretionary wedges intersect and overlap and define two of the three sides of the triangular Ionian abyssal plain. The internal structure of these morpho-tectonic provinces as well as the transition zones between them is also imaged by high-resolution 72-channel seismic reflection profiles. Together these data offer new insights into the interaction and competition between active sedimentary and tectonic processes shaping this part of the Central Mediterranean. Acknowledgment: The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement n° 603839 (Project ASTARTE - Assessment, Strategy and Risk Reduction for Tsunamis in Europe).

  1. Environmental Protection Tools in Agricultural Management Works

    NASA Astrophysics Data System (ADS)

    Glowacka, Agnieszka; Taszakowski, Jaroslaw; Janus, Jaroslaw; Bozek, Piotr

    2016-10-01

    Land consolidation is a fundamental instrument for agricultural management. It facilitates comprehensive changes in the agricultural, social, and ecological domains. Consolidation and post-consolidation development-related investments are an opportunity to improve living conditions in rural areas, and simultaneously ensure its positive impact on the environment. One of the primary goals of consolidation, directly specified in the Act on land consolidation, is to improve farming conditions. In Poland, consolidation is possible due to EU funds: RDP 2007-2013 and RDP 2014-2020. In order for individual villages to be granted EU funds for consolidation and post-consolidation development under the Rural Development Programme 2014-2020, their consolidation has to implement actions with positive impact on the environment and the landscape. The goal of this paper is to analyse documentation in the form of assumptions for a land consolidation project enclosed to an RDP 2014-2020 grant application and project information sheets as the basis for environmental impact assessment in the context of detailed presentation of environmental protection solutions that ensure a positive impact of the project on the environment and landscape. The detailed study involved 9 villages in the Malopolskie Voivodeship, which applied for EU grants for land consolidation in the current financial perspective. The paper specifies the existing state of the analysed villages as regards the natural environment, lists agricultural management instruments that have a positive impact on the environment, and demonstrates that planning of actions aimed at environmental protection is a necessary element of assumptions for land consolidation projects.

  2. Assessing and optimizing infrasound network performance: application to remote volcano monitoring

    NASA Astrophysics Data System (ADS)

    Tailpied, Dorianne; Le Pichon, Alexis; Marchetti, Emanuele; Ceranna, Lars; Pilger, Christopher

    2015-04-01

    Interest in infrasound propagation studies has been revived since the Comprehensive nuclear Test Ban Treaty (CTBT) was adopted in 1996. The International Monitoring System (IMS) is designed to ensure compliance with the CTBT by detecting and locating explosions in the world using at least 2 stations. Even not yet fully established, the infrasound network already allows studies on a global scale as it has demonstrated to be a major asset to remotely identify and analyze geophysical events such as volcanoes. Simulation methods incorporating realistic source and propagation effects have been developed to quantify the detection capability of this network. These methods can also be used to optimize the network configuration (number of stations, geographical location) in order to reduce the detection thresholds taking into account seasonal effects in infrasound propagation. Recent studies have shown that remote infrasound observations can provide useful information about eruption chronology and the released acoustic energy. Comparisons with near-field recordings allow evaluating the potential of these observations to better constrain source parameters when other monitoring techniques (satellite, seismic, gas) are not available or cannot be made. Because of its regular activity, the well-instrumented Mount Etna is in Europe a unique natural repetitive source to test and optimize detection and simulation methods. In summer, during the downwind season, its eruptions are quasi-permanently detected by IS48 in Tunisia, the closest infrasound station part of the IMS. Under the European ARISE project (Atmospheric dynamics InfraStructure in Europe, FP7/2007-2013), experimental arrays have been installed in order to characterize infrasound propagation in different ranges of distance and direction. Such an experimental setting offers an opportunity to address the societal benefits that can be achieved through routine infrasound monitoring.

  3. Use of vaginal estrogen in Danish women: a nationwide cross-sectional study.

    PubMed

    Meaidi, Amani; Goukasian, Irina; Lidegaard, Oejvind

    2016-03-01

    We know little about the use of vaginal estrogen in perimenopausal and postmenopausal women. We aimed to assess the prevalence of vaginal estrogen use in Denmark. The study was designed as a nationwide cross-sectional study of all Danish women aged 40-79 years, living in Denmark during the period 2007-2013. The Danish Prescription Register delivered data permitting us to assess the prevalence, age and regional geographical belonging of women purchasing prescribed vaginal estradiol. The number of women using over-the-counter vaginal estriol products was estimated from sale statistics from the same register. In 2013, 10.2% of all Danish women between 40 and 79 years of age used vaginal estradiol. The prevalence of women using this type of vaginal estrogen increased from 8.5% in year 2007 to 10.2% in 2013. The use peaked at 16.5% in women aged 60-74 years. The vaginal tablet was purchased more than the vaginal ring. We found no relevant difference in use between the five regions of Denmark. Taking the sale of vaginal estriol into account, the prevalence of vaginal estrogen use in 2013 could be estimated to a total of 12.1%. Comparing our result to the prevalence of urogenital atrophy-related symptoms reported in the literature, our study suggests an under-diagnosis and under-treatment of this condition. Teaching women and primary-care physicians about symptomatic urogenital atrophy and its treatment options may increase the quality of life for many women. © 2015 Nordic Federation of Societies of Obstetrics and Gynecology.

  4. Clinical Outcomes of Metastatic Poor Prognosis Germ Cell Tumors: Current Perspective From a Referral Center.

    PubMed

    Necchi, Andrea; Farè, Elena; Vullo, Salvatore Lo; Giannatempo, Patrizia; Raggi, Daniele; Nicolai, Nicola; Piva, Luigi; Biasoni, Davide; Catanzaro, Mario; Torelli, Tullio; Stagni, Silvia; Maffezzini, Massimo; Verzoni, Elena; Grassi, Paolo; Procopio, Giuseppe; Pizzocaro, Giorgio; Mariani, Luigi; Salvioni, Roberto

    2015-08-01

    Survival estimates with first-line treatment for patients with metastatic poor prognosis germ cell tumors (GCT) are still suboptimal in the literature. We conducted a retrospective study to evaluate the outcome of patients referred to our tertiary cancer center. A retrospective analysis was conducted on patients who received at least first-line chemotherapy at our center. Distribution of clinical characteristics was evaluated in the periods < 1997, 1997 to 2001, 2001 to 2006, and 2007 to 2013. The Kaplan-Meier method was used to estimate progression-free (PFS) and overall survival (OS). Univariable and multivariable Cox models with prespecified clinical variables were undertaken for PFS and OS. All tests and confidence intervals were 2-sided and set at a P = .05 level of significance. Between 1982 and 2013, 168 patients were identified. The median age was 27 years (interquartile range [IQR], 22-34). The presence of liver, bone, or brain metastases trended to greater incidence from 1997 onward (27.5% < 1997 to 55.6% in 2007-2013; χ(2)P = .054). Median follow-up was 102 (IQR, 63-166) months. Global 5-year PFS was 48.5% (95% confidence interval [CI], 41.5-56.8) and OS was 63.2% (95% CI, 56.0-71.2). In multivariable analysis, treatment period was not significantly associated with either PFS (overall P = .229) or OS (overall P = .216). In this single-center series of consecutive poor prognosis GCT we could observe greater PFS and OS than the historical estimates. This observation was independent from the period of treatment. Based on the present results, studies focused on improving the outcome in the sole poor-risk cohort should be discouraged. Results were biased by their retrospective quality. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. School absence and productivity outcomes associated with childhood asthma in the USA.

    PubMed

    Sullivan, Patrick; Ghushchyan, Vahram G; Navaratnam, Prakash; Friedman, Howard S; Kavati, Abhisek; Ortiz, Benjamin; Lanier, Bob

    2017-04-28

    Previous studies have examined the association between childhood asthma and lost productivity; however, more data are needed to understand its impact. This was a retrospective analysis of cross-sectional data in the nationally representative 2007-2013 Medical Expenditure Panel Survey (MEPS). School-aged children (SAC), children (age 6-11), and adolescents (age 12-17) with asthma were compared to those without asthma to examine annual missed school days. Adult parents/caregivers of SAC with asthma were compared to those of SAC without asthma to examine missed work days. The cost of premature asthma mortality for SAC was also estimated. Negative binomial regression was used for missed school days, and a two-part model structure was used for missed work days. All analyses controlled for sociodemographics and other covariates. There were 44,320 SAC of whom 5,890 had asthma. There were 43,496 employed adults with at least one child. SAC (6-17) with asthma missed 1.54 times the number of school days compared to SAC without asthma. Caregivers of SAC (6-17) with asthma missed 1.16 times the number of work days to care for others compared to caregivers of SAC without asthma. SAC in the USA missed an additional 7 million school days associated with asthma (3.7 million children and 3.3 million adolescent). There were 130 asthma deaths resulting in an annual cost of $211 million ($US 2015). Childhood asthma is associated with a significant school absence and productivity loss in the USA. Better treatment and asthma management programs are needed to alleviate this burden.

  6. National Prevalence of Poor Asthma Control and Associated Outcomes among School-Aged Children in the United States.

    PubMed

    Sullivan, Patrick W; Ghushchyan, Vahram; Navaratnam, Prakash; Friedman, Howard S; Kavati, Abhishek; Ortiz, Benjamin; Lanier, Bobby

    2017-08-25

    The degree of asthma control among school-aged children (SAC) nationally is not well understood. The objective of this study was to characterize poor control among SAC (aged 6-17 years) in the United States. This was a retrospective analysis of the 2007-2013 Medical Expenditure Panel Survey. Indicators of poor control included exacerbation in previous year; use of >3 canisters of short-acting β-agonist (SABA) in 3 months; and asthma-specific (AS) emergency department (ED) or inpatient (IP) visits. Treatment indicators included daily controller medication and peak flow meter use. Negative binomial regression was used for health resource utilization (HRU); generalized linear models with log-link were used for health care expenditures. There were 44,320 SAC, of whom 5,890 had asthma. The prevalence of poor control and treatment among SAC with asthma were as follows: exacerbation (59%), >3 canisters of SABA (4%), ED/IP visit (3%), daily controller (19%), peak flow (12%). In 2013, 3.4 million SAC had an asthma exacerbation and 200,000 had an AS ED/IP visit. SAC with asthma and an exacerbation had 18.9 times more annual AS ED visits (and 43.3 times more AS hospitalizations) than SAC with asthma but no exacerbation. SAC with asthma and an indicator of poor control incurred greater annual all-cause expenditures than SAC without asthma ($US 2015): $1,144 (exacerbation), $1,859 (≥3 canisters of SABA), and $3,063 (ED/IP visit). Use of daily controller medication was low even among SAC with poor control (27% to 61%). Renewed and vigilant asthma management and treatment is necessary to mitigate the current and long-term public health effects and expenditures associated with poor asthma control. Copyright © 2017 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  7. Unique Clones of Vibrio cholerae O1 El Tor with Haitian Type ctxB Allele Implicated in the Recent Cholera Epidemics from Nigeria, Africa.

    PubMed

    Adewale, Akinsinde Kehinde; Pazhani, Gururaja Perumal; Abiodun, Iwalokun Bamidele; Afolabi, Oluwadun; Kolawole, Olukoya Daniel; Mukhopadhyay, Asish K; Ramamurthy, Thanadarayan

    2016-01-01

    The antimicrobial susceptibility patterns and genetic characteristics of Vibrio cholerae O1, which is responsible for several cholera epidemics in Nigeria, are not reported in detail since 2007. In this study, we screened V. cholerae O1 El Tor biotype isolates from cholera cases and water samples from different states to investigate their phenotypic and genetic attributes with special reference to their clonality. All the V. cholerae O1 biotype El Tor isolates isolated during 2007-2013 were susceptible to fluoroquinolones and tetracycline, the drugs currently used in the treatment of cholera cases in Nigeria. Emergence of CT genotype 7 (Haitian type of ctxB allele) was predominantly seen among Ogawa serotype and the CT genotype 1 (classical ctxB allele) was mostly found in Inaba serotype. Overall, V. cholerae O1 from clinical and water samples were found to be closely related as determined by the pulsed-field gel electrophoresis. V. cholerae isolates from Abia, Kano and Bauchi were found to be genetically distinct from the other states of Nigeria. Fecal contamination of the water sources may be the possible source of the cholera infection. Combined prevalence of Haitian and classical ctxB alleles were detected in Ogawa and Inaba serotypes, respectively. This study further demonstrated that V. cholerae O1 with the ctxB has been emerged similar to the isolates reported in Haiti. Our findings suggest that the use of fluoroquinolones or tetracycline/doxycycline may help in the effective management of acute cholera in the affected Nigerian states. In addition, strengthening the existing surveillance in the hospitals of all the states and supply of clean drinking water may control cholera outbreaks in the future.

  8. A Systematic Content Analysis of Policy Barriers Impeding Access to Opioid Medication in Central and Eastern Europe: Results of ATOME.

    PubMed

    Larjow, Eugenia; Papavasiliou, Evangelia; Payne, Sheila; Scholten, Willem; Radbruch, Lukas

    2016-01-01

    Reliable access to opioid medication is critical to delivering effective pain management, adequate treatment of opioid dependence, and quality palliative care. However, more than 80% of the world population is estimated to be inadequately treated for pain because of difficulties in accessing opioids. Although barriers to opioid access are primarily associated with restrictive laws, regulations, and licensing requirements, a key problem that significantly limits opioid access relates to policy constraints. To identify and explore policy barriers to opioid access in 12 Eastern and Central European countries involved in the Access to Opioid Medication in Europe project, funded by the European Community's Seventh Framework (FP7/2007-2013, no. 222994) Programme. A systematic content analysis of texts retrieved from documents (e.g., protocols of national problem analyses, strategic planning worksheets, and executive summaries) compiled, reviewed, approved, and submitted by either the Access to Opioid Medication in Europe consortium or the national country teams (comprising experts in pain management, harm reduction, and palliative care) between September 2011 and April 2014 was performed. Twenty-five policy barriers were identified (e.g., economic crisis, bureaucratic issues, lack of training initiatives, stigma, and discrimination), classified under four predetermined categories (financial/economic aspects and governmental support, formularies, education and training, and societal attitudes). Key barriers related to issues of funding allocation, affordability, knowledge, and fears associated with opioids. Reducing barriers and improving access to opioids require policy reform at the governmental level with a set of action plans being formulated and concurrently implemented and aimed at different levels of social, education, and economic policy change. Copyright © 2016 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

  9. Variation in hospital performance for heart failure management in the National Heart Failure Audit for England and Wales.

    PubMed

    Emdin, Connor A; Conrad, Nathalie; Kiran, Amit; Salimi-Khorshidi, Gholamreza; Woodward, Mark; Anderson, Simon G; Mohseni, Hamid; Dargie, Henry J; Hardman, Suzanna M C; McDonagh, Theresa; McMurray, John J V; Cleland, John G F; Rahimi, Kazem

    2017-01-01

    Investigation of variations in provider performance and its determinants may help inform strategies for improving patient outcomes. We used the National Heart Failure Audit comprising 68 772 patients with heart failure with reduced left ventricular ejection fraction (HFREF), admitted to 185 hospitals in England and Wales (2007-2013). We investigated hospital adherence to three recommended key performance measures (KPMs) for inhospital care (ACE inhibitors (ACE-Is) or angiotensin receptor blockers (ARBs) on discharge, β-blockers on discharge and referral to specialist follow-up) individually and as a composite performance score. Hierarchical regression models were used to investigate hospital-level variation. Hospital-level variation in adherence to composite KPM ranged from 50% to 97% (median 79%), but after adjustments for patient characteristics and year of admission, only 8% (95% CI 7% to 10%) of this variation was attributable to variations in hospital features. Similarly, hospital prescription rates for ACE-I/ARB and β-blocker showed low adjusted hospital-attributable variations (7% CI 6% to 9% and 6% CI 5% to 8%, for ACE-I/ARB and β-blocker, respectively). Referral to specialist follow-up, however, showed larger variations (median 81%; range; 20%, 100%) with 26% of this being attributable to hospital-level differences (CI 22% to 31%). Only a small proportion of hospital variation in medication prescription after discharge was attributable to hospital-level features. This suggests that differences in hospital practices are not a major determinant of observed variations in prescription of investigated medications and outcomes. Future healthcare delivery efforts should consider evaluation and improvement of more ambitious KPMs. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  10. Overuse of helicopter transport in the minimally injured: A health care system problem that should be corrected.

    PubMed

    Vercruysse, Gary A; Friese, Randall S; Khalil, Mazhar; Ibrahim-Zada, Irada; Zangbar, Bardiya; Hashmi, Ammar; Tang, Andrew; O'Keeffe, Terrence; Kulvatunyou, Narong; Green, Donald J; Gries, Lynn; Joseph, Bellal; Rhee, Peter M

    2015-03-01

    Mortality benefit has been demonstrated for trauma patients transported via helicopter but at great cost. This study identified patients who did not benefit from helicopter transport to our facility and demonstrates potential cost savings when transported instead by ground. We performed a 6-year (2007-2013) retrospective analysis of all trauma patients presenting to our center. Patients with a known mode of transfer were included in the study. Patients with missing data and those who were dead on arrival were excluded from the study. Patients were then dichotomized into helicopter transfer and ground transfer groups. A subanalysis was performed between minimally injured patients (ISS < 5) in both the groups after propensity score matching for demographics, injury severity parameters, and admission vital parameters. Groups were then compared for hospital and emergency department length of stay, early discharge, and mortality. Of 5,202 transferred patients, 18.9% (981) were transferred via helicopter and 76.7% (3,992) were transferred via ground transport. Helicopter-transferred patients had longer hospital (p = 0.001) and intensive care unit (p = 0.001) stays. There was no difference in mortality between the groups (p = 0.6).On subanalysis of minimally injured patients there was no difference in hospital length of stay (p = 0.1) and early discharge (p = 0.6) between the helicopter transfer and ground transfer group. Average helicopter transfer cost at our center was $18,000, totaling $4,860,000 for 270 minimally injured helicopter-transferred patients. Nearly one third of patients transported by helicopter were minimally injured. Policies to identify patients who do not benefit from helicopter transport should be developed. Significant reduction in transport cost can be made by judicious selection of patients. Education to physicians calling for transport and identification of alternate means of transportation would be both safe and financially beneficial to our

  11. ISTIMES Integrated System for Transport Infrastructures Surveillance and Monitoring by Electromagnetic Sensing

    NASA Astrophysics Data System (ADS)

    Argenti, M.; Giannini, V.; Averty, R.; Bigagli, L.; Dumoulin, J.

    2012-04-01

    results has received funding from the European Community's Seventh Framework Programme (FP7/2007-2013) under Grant Agreement n° 225663

  12. Sensitivity analysis of vegetation indices to drought over two tallgrass prairie sites

    NASA Astrophysics Data System (ADS)

    Bajgain, Rajen; Xiao, Xiangming; Wagle, Pradeep; Basara, Jeffrey; Zhou, Yuting

    2015-10-01

    Vegetation growth is one of the important indicators of drought events. Greenness-related vegetation indices (VIs) such as Normalized Difference Vegetation Index (NDVI) and Enhanced Vegetation Index (EVI) are often used for the assessment of agricultural drought. There is a need to evaluate the sensitivity of water-related vegetation indices such as Land Surface Water Index (LSWI) to assess drought and associated impacts. Moderate-Resolution Imaging Spectroradiometer (MODIS) derived time series NDVI, EVI and LSWI data during 2000-2013 were compared for their sensitivity to drought at two tallgrass prairie sites in the Oklahoma Mesonet (Marena and El Reno). Each site has continuous soil moisture measurements at three different depths (5, 25 and 60 cm) and precipitation data for the study period (2000-2013) at 5-min intervals. As expected, averaged values of vegetation indices consistently lower under drought conditions than normal conditions. LSWI decreased the most in drought years (2006, 2011 and 2012) when compared to its magnitudes in pluvial years (2007, 2013), followed by EVI and NDVI, respectively. Because green vegetation has positive LSWI values (>0) and dry vegetation has negative LSWI values (<0), much longer durations of LSWI < 0 were found in the summer periods of drought years rather than in pluvial years. A LSWI-based drought severity scheme (LSWI > 0.1; 0 < LSWI ⩽ 0.1; -0.1 < LSWI ⩽ 0; LSWI ⩽ -0.1) corresponded well with the drought severity categories (0; D0; D1: D2; D3 and D4) defined by the United States Drought Monitor (USDM) at these two study sites. Our results indicate that the number of days with LSWI < 0 during the summer and LSWI-based drought severity scheme can be simple, effective and complementary indicator for assessing drought in tallgrass prairie grasslands at a 500-m spatial resolution.

  13. A better surgical resectability of WHO grade II gliomas is independent of favorable molecular markers.

    PubMed

    Cordier, Dominik; Gozé, Catherine; Schädelin, Sabine; Rigau, Valérie; Mariani, Luigi; Duffau, Hugues

    2015-01-01

    A higher extent of resection (EOR) in WHO grade II gliomas (GIIG) is correlated with longer survival. However, the molecular markers also feature prognostic relevance. Here, we examined whether maximal EOR was related to the genetic profile. We retrospectively investigated the predictive value of 1p19q, IDH1, 53 expression and Ki67 index for the EOR in 200 consecutive GIIGs (2007-2013). Data were modeled in a linear model. The analysis was performed with two statistical methods (arcsin-sqrt and Beta-regression model with logit link). There was no deletion 1p19q in 118 cases, codeletion 1p19q (57 cases), single deletion 1p (4 cases) or19q (16 cases). 155 patients had a mutation of IDH1. p53 was graded in 4 degrees (0:92 cases, 1:52 cases, 2:31 cases, 3:8 cases). Mean Ki67 index was 5.2 % (range 1-20 %). Mean preoperative tumor volume was 60.8 cm(3) (range 3.3-250 cm(3)) and mean EOR was 0.917 (range 0.574-1). The statistical analysis was significant for a lower EOR in patients with codeletion 1p19q (OR 0.738, p = 0.0463) and with a single deletion 19q (OR 0.641, p = 0.0168). There was no significant correlation between IDH1 or p53 and the EOR. Higher Ki67 was marginally associated with higher EOR (p = 0.0603). The study demonstrates in a large cohort of GIIG that a higher EOR is not attributable to favorable genetic markers. This original result supports maximal surgical resection as an important therapeutic factor per se to optimize prognosis, independently of the molecular pattern.

  14. The Global and Local Characters of Mars Perihelion Cloud Trails

    NASA Astrophysics Data System (ADS)

    Clancy, R. T.; Wolff, M. J.; Smith, M. D.; Cantor, B. A.; Spiga, A.

    2014-12-01

    We present the seasonal and spatial distribution of Mars perihelion cloud trails as mapped from Mars Reconnaissance Orbiter (MRO) MARCI (Mars Color Imager) imaging observations in 2 ultraviolet and 3 visible filters. The extended 2007-2013 period of MARCI daily global image maps reveals the widespread distribution of these high altitude clouds, which are somewhat paradoxically associated with specific surface regions. They appear as longitudinally extended (300-700 km) cloud trails with distinct leading plumes of substantial ice cloud optical depths (0.02-0.2) for such high altitudes of occurrence (40-50 km, from cloud surface shadow measurements). These plumes generate small ice particles (Reff~1 to <0.2 microns) that become entrained in the strong westward mesospheric zonal wind regime of the perihelion (southern summer ) season, although the specific dynamics and cloud microphysics for these plumes are not determined. They are clearly tied to maximum surface heating on Mars, in terms of season (perihelion), local time (early afternoon), and surface latitude/albedo/elevation. The most persistent expressions of these clouds are found in association with two Valles Marineris locations (Clancy et al., 2009). However, a broader survey of MARCI observations reveals many specific regions of occurrence over Ls=200-300. Furthermore, MRO CRISM limb observations indicate a haze of such fine water ice particles characterizes the full southern hemisphere mesosphere at this time. Hence, the behavior of perihelion cloud trails appears to reflect locally elevated mesospheric water ice formation that may impact the global expression of mesospheric water ice aerosols.

  15. Irradiation effect on deuterium behaviour in low-dose HFIR neutron-irradiated tungsten

    DOE PAGES

    Shimada, Masashi; Cao, G.; Otsuka, T.; ...

    2014-12-01

    Tungsten samples were irradiated by neutrons in the High Flux Isotope Reactor, Oak Ridge National Laboratory at reactor coolant temperatures of 50-70°C to low displacement damage of 0.025 and 0.3 dpa under the framework of the US-Japan TITAN program (2007-2013). After cooling down, the HFIR neutron-irradiated tungsten samples were exposed to deuterium plasmas in the Tritium Plasma Experiment, Idaho National Laboratory at 100, 200 and 500 °C twice at the ion fluence of 5×10²⁵ m⁻² to reach a total ion fluence of 1×10²⁶ m⁻² in order to investigate the near surface deuterium retention and saturation via nuclear reaction analysis. Finalmore » thermal desorption spectroscopy was performed to elucidate irradiation effect on total deuterium retention. Nuclear reaction analysis results showed that the maximum near surface (<5 µm depth) deuterium concentration increased from 0.5 at % D/W in 0.025 dpa samples to 0.8 at. % D/W in 0.3 dpa samples. The large discrepancy between the total retention via thermal desorption spectroscopy and the near surface retention via nuclear reaction analysis indicated the deuterium was migrated and trapped in bulk (at least 50 µm depth for 0.025 dpa and 35 µm depth for 0.025 dpa) at 500 °C case even in the relatively low ion fluence of 10²⁶ m⁻².« less

  16. Temporal trends and spatial variation characteristics of primary air pollutants emissions from coal-fired industrial boilers in Beijing, China.

    PubMed

    Xue, Yifeng; Tian, Hezhong; Yan, Jing; Zhou, Zhen; Wang, Junling; Nie, Lei; Pan, Tao; Zhou, Junrui; Hua, Shenbing; Wang, Yong; Wu, Xiaoqing

    2016-06-01

    Coal-fired combustion is recognized as a significant anthropogenic source of atmospheric compounds in Beijing, causing heavy air pollution events and associated deterioration in visibility. Obtaining an accurate understanding of the temporal trends and spatial variation characteristics of emissions from coal-fired industrial combustion is essential for predicting air quality changes and evaluating the effectiveness of current control measures. In this study, an integrated emission inventory of primary air pollutants emitted from coal-fired industrial boilers in Beijing is developed for the period of 2007-2013 using a technology-based approach. Future emission trends are projected through 2030 based on current energy-related and emission control policies. Our analysis shows that there is a general downward trend in primary air pollutants emissions because of the implementation of stricter local emission standards and the promotion by the Beijing municipal government of converting from coal-fired industrial boilers to gas-fired boilers. However, the ratio of coal consumed by industrial boilers to total coal consumption has been increasing, raising concerns about the further improvement of air quality in Beijing. Our estimates indicate that the total emissions of PM10, PM2.5, SO2, NOx, CO and VOCs from coal-fired industrial boilers in Beijing in 2013 are approximately 19,242 t, 13,345 t, 26,615 t, 22,965 t, 63,779 t and 1406 t, respectively. Under the current environmental policies and relevant energy savings and emission control plans, it may be possible to reduce NOx and other air pollutant emissions by 94% and 90% by 2030, respectively, if advanced flue gas purification technologies are implemented and coal is replaced with natural gas in the majority of existing boilers.

  17. Real-world evaluation of the effectiveness of reversing camera and parking sensor technologies in preventing backover pedestrian injuries.

    PubMed

    Keall, M D; Fildes, B; Newstead, S

    2017-02-01

    Backover injuries to pedestrians are a significant road safety issue, but their prevalence is underestimated as the majority of such injuries are often outside the scope of official road injury recording systems, which just focus on public roads. Based on experimental evidence, reversing cameras have been found to be effective in reducing the rate of collisions when reversing; the evidence for the effectiveness of reverse parking sensors has been mixed. The wide availability of these technologies in recent model vehicles provides impetus for real-world evaluations using crash data. A logistic model was fitted to data from crashes that occurred on public roads constituting 3172 pedestrian injuries in New Zealand and four Australian States to estimate the odds of backover injury (compared to other sorts of pedestrian injury crashes) for the different technology combinations fitted as standard equipment (both reversing cameras and sensors; just reversing cameras; just sensors; neither cameras nor sensors) controlling for vehicle type, jurisdiction, speed limit area and year of manufacture restricted to the range 2007-2013. Compared to vehicles without any of these technologies, reduced odds of backover injury were estimated for all three of these technology configurations: 0.59 (95% CI 0.39-0.88) for reversing cameras by themselves; 0.70 (95% CI 0.49-1.01) for both reversing cameras and sensors; 0.69 (95% CI 0.47-1.03) for reverse parking sensors by themselves. These findings are important as they are the first to our knowledge to present an assessment of real-world safety effectiveness of these technologies.

  18. Pattern of radiotherapy care in Bulgaria.

    PubMed

    Hadjieva, Tatiana

    2015-01-01

    The paper reveals the changing pattern of Bulgarian Radiotherapy (RT) care after the successful implementation of 15 projects for 100 million euro under the European Regional Development Fund in Operational Programme for Regional Development 2007-2013. The project enables a total one-step modernization of 14 Bulgarian RT Centres and creation of a new one. At the end of the Programme (mid 2015), 16 new Linacs and 2 modern cobalt machines will be available together with 11 virtual CT simulators, 5 CT simulators, 1 MRI and 1 PET CT for RT planning and all dosimetry facilities needed. Such a modernization has moved Bulgarian RT forward, with 2.7 MV units per one million of population (MV/mln.inh) in comparison with 0.9 MV/mln.inh in 2012. Guild of Bulgarian Radiotherapists includes 70 doctors, 46 physicists and 10 engineers, together with 118 RTTs and 114 nurses and they all have treated 16,447 patients in 2013. Major problems are inadequate reimbursement from the monopolistic Health Insurance Fund (900 euro for 3D conformal RT and 1500 euro for IMRT); fragmentation of RT care with 1-2 MV units per Centre; no payment for patient travel expenses; need for quick and profound education of 26% of doctors and 46% of physicists without RT license, along with continuous education for all others; and resource for 5000-9000 more patients to be treated yearly by RT in order to reach 45-50% from current service of 32%. After 15 years of struggle of RT experts, finally the pattern of Bulgarian RT care at 2014-2015 is approaching the level of modern European RT.

  19. Sensitivity of Three Vegetation Indices to Cimate and Soil moisture at a Tallgrass Prairie Site

    NASA Astrophysics Data System (ADS)

    Bajgain, R.; Xiao, X.; Wagle, P.; Basara, J. B.

    2014-12-01

    Climatic variability influence vegetation condition and growth, which are often characterized by satellite derived vegetation indices (VIs) such as normalized difference vegetation Index (NDVI), enhanced vegetation Index (EVI) and land surface water index (LSWI). A fourteen-year (2000 - 2013) of NDVI, EVI and LSWI data from Moderate-Resolution Imaging Spectroradiometer (MODIS) were analyzed for assessing grassland vegetation dynamics to climatic variability ( i.e., drought) and soil moisture over the time series at the Marena site, Stillwater Oklahoma,USA. This is also the Marena, Oklahoma In-situ Sensor Testbed (MOISST) site in support of NASA SMAP mission. Change in magnitudes of VIs provided the dynamics of inter-annual variability of the grassland vegetation. The magnitude of VIs declined in dry years (2006 and 2012) .Variation in NDVI and EVI over years resulting from climatic variability was strongly correlated to cumulative seasonal rainfall (NDVI, r = 0.82, EVI, r = 0.77) and average seasonal soil volumetric water content up to 60 cm depth. The EVI declined more than did NDVI during the dry events of 2006 and 2012, indicating that the use of EVI in place of NDVI appears to increase the performance of ecosystem models under drought condition. Furthermore, LSWI was the most sensitive index to drought among the three VIs tested. The LSWI values were negative (LSWI < 0) even within the middle of plant growing season in dry years, showing its potential to track the hydrological status of the ecosystem. Duration of LSWI < 0 in summer was greater in dry years (2006= 53 & 2012= 34 days) compared to wet years (2007 & 2013= 0 days). The result also revealed that LSWI values quantitatively corresponded well with the drought severity categories identified by the United States Drought Monitoring (USDM). In conclusion, the number of days with LSWI < 0 during the plant growing season and LSWI-based drought severity classification scheme can provide useful information for

  20. Structure and sources of solar wind in the growing phase of 24th solar cycle

    NASA Astrophysics Data System (ADS)

    Slemzin, Vladimir; Goryaev, Farid; Shugay, Julia; Rodkin, Denis; Veselovsky, Igor

    2015-04-01

    We present analysis of the solar wind (SW) structure and its association with coronal sources during the minimum and rising phase of 24th solar cycle (2009-2011). The coronal sources prominent in this period - coronal holes, small areas of open magnetic fields near active regions and transient sources associated with small-scale solar activity have been investigated using EUV solar images and soft X-ray fluxes obtained by the CORONAS-Photon/TESIS/Sphinx, PROBA2/SWAP, Hinode/EIS and AIA/SDO instruments as well as the magnetograms obtained by HMI/SDO. It was found that at solar minimum (2009) velocity and magnetic field strength of high speed wind (HSW) and transient SW from small-scale flares did not differ significantly from those of the background slow speed wind (SSW). The major difference between parameters of different SW components was seen in the ion composition represented by the C6/C5, O7/O6, Fe/O ratios and the mean charge of Fe ions. With growing solar activity, the speed of HSW increased due to transformation of its sources - small-size low-latitude coronal holes into equatorial extensions of large polar holes. At that period, the ion composition of transient SW changed from low-temperature to high-temperature values, which was caused by variation of the source conditions and change of the recombination/ionization rates during passage of the plasma flow through the low corona. However, we conclude that criteria of separation of the SW components based on the ion ratios established earlier by Zhao&Fisk (2009) for higher solar activity are not applicable to the extremely weak beginning of 24th cycle. The research leading to these results has received funding from the European Commission's Seventh Framework Programme (FP7/2007-2013) under the grant agreement eHeroes (project n° 284461, www.eheroes.eu).

  1. Surveying the Underwater Arcaheological Site of Cape Glaros at Pagasetikos Gulf

    NASA Astrophysics Data System (ADS)

    Diamanti, E.; Spondylis, E.; Vlachaki, F.; Kolyva, E.

    2017-02-01

    The Hellenic Institute of Marine Archaeology (H.I.M.A.)1 has been conducting an underwater archaeological research in the west coast of southern Pagasetikos Gulf, since 2000. Every year the underwater research focuses on specific archaeological targets that have been recovered during previous field campaigns. The current publication elaborates on the comprehensive documentation of the underwater archaeological site at Cape Glaros, during the 2015 field season, under the direction of the archaeologist Elias Spondylis. The 2015 research campaign was conducted within the framework of the ITACA- Innovation Technologies and Applications for Coastal Archaeological sites European Project (FP7/2007-2013, GA No 606805), at two archaeological sites, namely the Cape Glaros and Metohi. It was among the most important challenges of the project to successfully produce the detailed and accurate 3D mapping of the Cape Glaros site that covers an extended area. Four large concentrations of pottery finds and numerous anchors of different typology have been recorded, that can be dated from the late Hellenistic to the Byzantine periods. This challenge was tackled through the simultaneous implementation of three recording methods; photogrammetry, geodesy and conventional architectural mapping. The workflow of the documentation process, including data acquisition, processing and graphic visualization, along with the derived results are presented below. 1The Hellenic Institute of Marine Archaeology (H.I.M.A.) is a private, non-profit organization, founded in 1973, which undertakes maritime archaeological research under the supervision or in collaboration with the Greek Ministry of Culture. It has over 100 members, with diverse academic credentials, all of whom work, mainly, on a voluntary basis. 3D recording of underwater archaeological sites has been applied to numerous projects that have been carried out by the multidisciplinary team of H.I.M.A. in locations of utmost archaeological

  2. Geologic map of the eastern quarter of the Flagstaff 30’ x 60’ quadrangle, Coconino County, northern Arizona

    USGS Publications Warehouse

    Billingsley, George H.; Block, Debra L.; Hiza-Redsteer, Margaret

    2014-01-01

    The eastern quarter of the Flagstaff 30′ x 60′ quadrangle includes eight USGS 1:24,000-scale quadrangles in Coconino County, northern Arizona (fig. 1, map sheet): Anderson Canyon, Babbitt Wash, Canyon Diablo, Grand Falls, Grand Falls SE, Grand Falls SW, Grand Falls NE, and Meteor Crater. The map is bounded by lat 35° to 35°30′ N. and long 111° to 111°15′ W. and is on the southern part of the Colorado Plateaus geologic province (herein Colorado Plateau). Elevations range from 4,320 ft (1,317 m) at the Little Colorado River in the northwest corner of the map area to about 6,832 ft (2,082 m) at the southwest corner of the map. This geologic map provides an updated geologic framework for the eastern quarter of the Flagstaff 30′ x 60′ quadrangle and is adjacent to two other recent geologic maps, the Cameron and Winslow 30′ x 60′ quadrangles (Billingsley and others, 2007, 2013). This geologic map is the product of a cooperative effort between the U.S. Geological Survey (USGS) and the Navajo Nation. It provides geologic information for resource management officials of the U.S. Forest Service, the Arizona Game and Fish Department, and the Navajo Nation Reservation (herein the Navajo Nation). Funding for the map was provided by the USGS geologic mapping program, Reston, Virginia. Field work on the Navajo Nation was conducted under a permit from the Navajo Nation Minerals Department. Any persons wishing to conduct geologic investigations on the Navajo Nation must first apply for, and receive, a permit from the Navajo Nation Minerals Department, P.O. Box 1910, Window Rock, Arizona 86515, telephone (928) 871-6587.

  3. Ionospheric Effects of Sudden Stratospheric Warming During Solar Maximum and Minimum Periods: What Do We See from Puerto Rico?

    NASA Astrophysics Data System (ADS)

    Hernandez-Espiet, A.; Goncharenko, L. P.; Spraggs, M. E.; Coster, A. J.; Galkin, I. A.; Aponte, N.

    2014-12-01

    Some of the main factors that contribute to changes in multiple ionospheric parameters are solar flux, geomagnetic activity, seasonal behavior, and coupling with lower atmosphere, which is particularly strong during sudden stratospheric warming events (SSW). Studying the way that these factors induce changes in the ionosphere is important, since these changes can have a negative effect on different types of communication systems. Multiple case studies have demonstrated large variations in ionospheric electron density in association with SSW in the low-latitude ionosphere, in particular near the crests of the equatorial ionization anomaly. However, the latitudinal extend of these variations was not addressed. In this study, we utilize data obtained in Puerto Rico by three instruments - Ramey digisonde, Arecibo Incoherent Scatter Radar (ISR) and GPS receivers to analyze four winter-time periods: two years with major SSW events (2005-2006, 2012-2013) and two years with minor SSW events (2006-2007, 2013-2014). In addition, selected cases represent two winters with low solar activity and two winters with moderate to high solar activity. The study focuses on the location of Arecibo, Puerto Rico (18.34°N, 66.75°W), ~15° to the north of the northern crest of the equatorial ionization anomaly. We report good agreement in ionospheric parameters between all three instruments. To investigate possible association with SSW events, we remove influences of seasonal behavior, solar flux, and geomagnetic activity by building empirical model and subtracting expected variations from the observational data. The analysis of residuals between the data and the model shows that ionospheric disturbances were observed in Puerto Rico for both minor and major SSW events in the ISR, digisonde and GPS Total Electron Content (TEC) data. We report 20-60% variations in NmF2 and TEC due to SSW effects. Large variations are also observed in electron density, electron temperature and plasma

  4. Is Walk Score associated with hospital admissions from chronic diseases? Evidence from a cross-sectional study in a high socioeconomic status Australian city-state.

    PubMed

    Mazumdar, Soumya; Learnihan, Vincent; Cochrane, Thomas; Phung, Hai; O'Connor, Bridget; Davey, Rachel

    2016-12-08

    To explore patterns of non-communicable diseases (NCDs) in the Australian Capital Territory (ACT).To ascertain the effect of the neighbourhood built environmental features and especially walkability on health outcomes, specifically for hospital admissions from NCDs. A cross-sectional analysis of public hospital episode data (2007-2013). Hospitalisations from the ACT, Australia at very small geographic areas. Secondary data on 75 290 unique hospital episodes representing 39 851 patients who were admitted to ACT hospitals from 2007 to 2013. No restrictions on age, sex or ethnicity. Geographic Information System derived or compatible measures of general practitioner access, neighbourhood socioeconomic status, alcohol access, exposure to traffic and Walk Score walkability. Hospitalisations of circulatory diseases, specific endocrine, nutritional and metabolic diseases, respiratory diseases and specific cancers. Geographic clusters with significant high and low risks of NCDs were found that displayed an overall geographic pattern of high risk in the outlying suburbs of the territory. Significant relationships between neighbourhood walkability as measured by Walk Score and the likelihood of hospitalisation with a primary diagnosis of myocardial infarction (heart attack) were found. A possible relationship was also found with the likelihood of being hospitalised with 4 major lifestyle-related cancers. Our research augments the growing literature underscoring the relationships between the built environment and health outcomes. In addition, it supports the importance of walkable neighbourhoods, as measured by Walk Score, for improved health. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  5. The definition of placebo in the informed consent forms of clinical trials.

    PubMed

    Hernández, Astrid; Baños, Josep-E; Llop, Cristina; Farré, Magí

    2014-01-01

    Lack of knowledge concerning the nature of placebo and why it is necessary may influence the participation of patients in clinical trials. The objective of the present study is to review how placebo is described in written information for participants in clinical trials to be evaluated by a Human Research Ethics Committee. All research protocols submitted for evaluation in a Spanish hospital during 2007-2013 were reviewed. The main characteristics of the studies using a placebo were collected. Three authors read each of them to determine how the term "placebo" was explained and if there was any comment on its efficacy and safety. Two thousand seven-hundred and forty research protocols were evaluated, of which three hundred and fifty-nine used a placebo. Pharmaceutical companies sponsored most placebo-controlled clinical trials (91.9%), and phase III studies were the commonest (59.9%). Oncology (15.0%), cardiology (14.2%), and neurology (13.1%) made the greatest contributions. A review of the informed consent forms showed that placebo was described in a similar manner in most studies: the explanation was limited to between four and eight words. Very few gave information about the risks of its use or adverse reactions from its administration. None of the studies provided details about the placebo effect. And 23 lacked any information about placebo at all. Explanations about placebo in informed consent forms is often scarce, and information about the placebo effect and associated risks are absent. This situation may influence a full understanding of placebo by participants in clinical trials and might reduce their informed decision to participate.

  6. Reframing the impact of combined heart-liver allocation on liver transplant waitlist candidates

    PubMed Central

    Goldberg, David S.; Reese, Peter P.; Amaral, Sandra; Abt, Peter L.

    2014-01-01

    Simultaneous heart-liver transplantation, although rare, has become more common in the U.S. When the primary organ is a heart or liver, patients receiving an offer for the primary organ automatically receive the second, non-primary organ from that donor. This policy raises issues of equity—i.e. whether liver transplant-alone candidates bypassed by heart-liver recipients are disadvantaged. No prior published analyses have addressed this issue, and few methods have been developed as a means to measure the impact of such allocation policies. We analyzed OPTN match run data from 2007-2013 to determine whether this combined organ allocation policy disadvantages bypassed liver transplant waitlist candidates in a clinically meaningful way. Among 65 heart-liver recipients since May 2007, 42 had substantially higher priority for the heart relative to the liver, and bypassed 268 liver-alone candidates ranked 1-10 on these match runs. Bypassed patients had lower risk of waitlist removal for death or clinical deterioration compared to controls selected by match MELD score (HR: 0.56, 95% CI: 0.40-0.79), and similar risk as controls selected by laboratory MELD score (HR: 0.91, 95% CI: 0.63-1.33) or on match runs of similar graft quality (HR: 0.97, 95% CI: 0.73-1.37). The waiting time from bypass to subsequent transplantation was significantly longer among bypassed candidates versus controls on match runs of similar graft quality (median: 87 (IQR: 27-192) days versus 24 (5-79) days; p<0.001). Although transplant is delayed, liver transplant waitlist candidates bypassed by heart-liver recipients do not have excess mortality compared to three sets of matched controls. These analytic methods serve as a starting point to consider other potential approaches to evaluate the impact of multi-organ transplant allocation policies PMID:25044621

  7. Factors associated with prolonged ventilation and reintubation in adult spinal deformity surgery.

    PubMed

    De la Garza Ramos, Rafael; Nakhla, Jonathan; Nasser, Rani; Jada, Ajit; Purvis, Taylor E; Sciubba, Daniel M; Kinon, Merrit; Yassari, Reza

    2017-09-01

    Prolonged ventilation or reintubation are severe complications after scoliosis surgery, but there is limited data regarding their incidence and risk factors. The purpose of this study is to investigate the incidence and risk factors for prolonged ventilation and reintubation in adult spinal deformity (ASD) surgery. The American College of Surgeons National Surgical Quality Improvement Program database (2007-2013) was reviewed. Inclusion criteria were adult patients over 21years of age who underwent spinal fusion for ASD. The association between patient/operative characteristics and prolonged ventilation/reintubation was investigated via multivariate analysis. Results are presented as odds ratios (OR) with 95% confidence intervals (CI). There were 1250 patients who underwent ASD surgery and met our inclusion criteria. Among these, there were 34 patients who required prolonged ventilation (2.7%) and 22 patients who underwent reintubation (1.8%). Factors associated with prolonged ventilation after multivariate analysis were history of bleeding disorder (OR 5.67; 95% CI, 1.01-31.83) and operative time over 6h (OR 3.72; 95% CI, 1.17-11.80). For reintubation, these included older age (OR 1.06; 95% CI, 1.01-1.12), history of bleeding disorder (OR 12.21; 95% CI, 2.03-73.42), and fusion of 13 or more spinal levels (OR 9.14; 95% CI, 1.53-54.63). In conclusion, prolonged ventilation and reintubation in ASD surgery are uncommon events. Older patients, patients with bleeding disorders, and those undergoing long operations and fusion of 13 more spinal segments may be at an increased risk for these occurrences. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. SWIR spectral mapping of the Martian South Polar Residual Cap using CRISM

    NASA Astrophysics Data System (ADS)

    Campbell, Jacqueline; Sidiropoulos, Panagiotis; Muller, Jan-Peter

    2016-10-01

    to these results has received partial funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under iMars grant agreement no. 607379.

  9. The Ofidia Project: a Retrospective Fire Danger Forecast Analysis in Mediterranean Environment

    NASA Astrophysics Data System (ADS)

    Sirca, C.; Bacciu, V. M.; Salis, M.; Mirto, L.; Fiore, S.; Aloisio, G.; Spano, D.

    2015-12-01

    OFIDIA (Operational FIre Danger preventIon plAtform) is a two-year project started in May 2013 funded by the European Territorial Cooperation Programme Greece Italy (2007 - 2013). The project aims to improve the operational capability of forecasting, preventing, and fighting forest wildfires, and enhance the cross-border cooperation for fire danger assessment. More specifically, OFIDIA aims at developing an operational fire danger prevention platform, with the ability for near real-time fire danger forecast and fire behaviour analysis in Apulia (Italy) and Epirus (Greece) regions to help forest fires services in the effective prevention and response to forecasted danger.One of the preliminary activities of the project was the evaluation of fire danger performances by analysing the relationship between the predicted daily fire danger and observed fire activity (number of fires and area burned). To achieve this task, fire activity and danger patterns were characterised and their relationships were investigated for the period 2000-2012. The Italian Forest Service (CFS, Corpo Forestale dello Stato) provided fire statistics at NUT03 level. The data were homogenized and uncertainties corrected, and then burned area and number of fires were analysed according to the main fire regime characteristics (seasonality, fire return interval, fire incidence, fire size distribution, etc). Then, three fire danger models (FFWI, FWI, and IFI) were selected and computed starting from the fifth-generation Pennsylvania State University-National Center for Atmospheric Research Mesoscale Model (MM5) forecast.Results showed a high inter- and intra-annual variability in fire activiy, also considering the different type of affected vegetation. As for other Mediterranean areas, a smaller number of large fires caused a high proportion of burned area. Furthermore, fire activity showed significant correlations with the outputs obtained by the applied models. High relationships were found between

  10. Model based historical runoff contribution from an Alpine glacier

    NASA Astrophysics Data System (ADS)

    Zoccatelli, Davide; Bonato, Paola; Carturan, Luca; Dalla Fontana, Giancarlo; De Blasi, Fabrizio; Borga, Marco

    2016-04-01

    The aim of this work is to analyze how climatic variability and glacier retreat impact the water balance of a small (8.5 km2) glaciarised catchment in the Eastern Italia Alps over a 30 year (1983-2013) period. The analysis is carried out by coupling local high quality data and a glacio-hydrological model able to simulate both the glacier and hydrology dynamics. Runoff contribution from glacier ice is related with trends in climatic variables and with glacier retreat. The area analyzed is the headwater of Noce Bianco river basin, lying in the Ortles-Cevedale group and including the La Mare glacier. During the study period the glacier area decreased from 4.7 km2 (50% basin area) to 3.47 km2 (40% basin area). In this area the following observations are available: 30 years of daily meteorological data at high elevation close to the catchment; three DTMs of the glacier, covering the entire period, which enable the calculation of the volume change and geodetic mass balance; direct glaciological mass balance observations over the period 2003-2013; discharge measurement at the catchment outlet over the period 2007-2013. The data availability and the significant shrinking of the glacier during the analyzed period make this catchment ideal for studying the hydrological impacts of glacier retreat. The semi-distributed conceptual model includes a snow and glacier accumulation and ablation module, based on temperature-radiation index and a glacier retreat model. The glacier retreat model allows to use the annual simulated glacier mass balance to update the glacier area (Huss et al., 2010). The model simulations are carried out from 1983 to 2013. We show that the model is able to capture adequately the measured daily discharge, the observed changes in glacier area and their spatial distribution. The contribution of glacier ice meltwater to annual runoff is below 10% in the first decade of simulation. This variable however showed a clear increasing trend, with peaks for single

  11. Volcanic Ash Monitoring and FOrecaSting between Sicilia and Malta arEa and sharinG of the resUlts foR aviatiOn safety: the VAMOS SEGURO project

    NASA Astrophysics Data System (ADS)

    Scollo, Simona; Azzopardi, Francelle; Boselli, Antonella; Coltelli, Mauro; Ellul, Raymond; Leto, Giuseppe; Pisani, Gianluca; Prestifilippo, Michele; Saliba, Martin; Schiavone, Joseph; Spata, Gaetano; Spinelli, Nicola; Wang, Xuan; Zanmar Sanchez, Ricardo

    2013-04-01

    Mt. Etna, in Italy, is one of the most active volcanoes in the world and during its frequent explosive episodes, eruption columns rise to several kilometers and fine ash is dispersed hundreds kilometers away from the vent reaching the neighboring countries. The Maltese Islands, for example, are situated at the center of the Mediterranean, only 100 km south of Sicily and, due to the close proximity, have been already affected by the past Etna volcanic activity. A reliable monitoring and forecasting system of Etna volcanic ash has to include all areas that could be reached by volcanic ash. For this reason, a new research project named VAMOS SEGURO, has been recently funded by Programma di Cooperazione Transfrontaliera Italia-Malta 2007-2013, with the aim to reduce the impact that Etna's explosive activity has in the area between Sicily and Malta. This project is developed within a cooperation between the Istituto Nazionale di Geofisica, Osservatorio Etneo, the Istituto Nazionale di Astrofisica (INAF), Comune of Montedoro, in Caltanissetta, the University of Malta, and Consorzio Interuniversitario per le Scienze Fisiche della Materia (CNISM). In this project, several instruments (e.g. aerosol optical depth analyzer, microbalance, laser cascade instrument, meteorological stations, aethelometer) have been installed at Giordan lighthouse at Xewkija, in Gozo, managed by the University of Malta. Furthermore, an innovative Lidar system with scanning capability, has been designed and realized by CNISM and is able to indentify the area affected by volcanic ash in Sicily and quantify the ash concentration in atmosphere. The Lidar may be transported and installed in the INAF astronomical observatories of Noto and Serra La Nave, only 7 km away from the Etna summits, and in Montedoro. Finally, an automatic forecasting system produces dispersal maps for the region between Sicily and Malta and for a typical Etna scenario. Results of simulations are daily visible at www

  12. An improved real-time seismic network in the Central Mediterranean

    NASA Astrophysics Data System (ADS)

    Agius, Matthew; Galea, Pauline; D'Amico, Sebastiano

    2014-05-01

    The Central Mediterranean is a region of active tectonics characterised by the interaction of a number of varied and sometimes poorly understood processes. Superimposed on the convergent scenario of the African plate pushing northwestward, a NE-SW directed extensional regime is active in the Sicily Channel, expressed in the form of a seismically active east-west trending system of strike-slip lineaments and a series of pull-apart grabens. The offshore seismicity of the Sicily channel, generally limited to magnitudes below 4.5, is normally difficult to quantify precisely, due to poor station coverage, yet it is believed that its analysis will considerably improve our understanding of the processes affecting the region. We present recent improvements to real and virtual seismic networking in the Central Mediterranean, based at the Seismic Monitoring and Research Unit (SMRU), University of Malta. Within the project SIMIT (B1-2.19/11) funded by the Italia-Malta Operational Programme 2007-2013, earthquake monitoring on the Maltese Islands is being upgraded through the installation of a further two broadband stations, one of which will be on the smaller island of Gozo. A new network, ML (Malta Seismic Network), has been internationally registered with the FDSN. At the same time, the installation and implementation of SeisComP3 has enabled the setting up of a virtual, real-time Central Mediterranean network, made up of 18 stations in Southern Italy (including Sicily, Lampedusa and Pantelleria) belonging to the Istituto Nazionale di Geofisica e Vulcanologia, 3 stations in Tunisia (National Institute of Meteorology of Tunisia) and the 3 stations on the Maltese Islands. This will allow us to rapidly perform more accurate hypocentral locations in the region. The virtual network, which also incorporates a number of more distant stations, has been tuned to issue SMS alerts for potentially felt events in the Sicily Channel detected by the network, and for strong earthquakes

  13. Recent developments in the setting up of the Malta Seismic Network

    NASA Astrophysics Data System (ADS)

    Agius, Matthew; Galea, Pauline; D'Amico, Sebastiano

    2015-04-01

    Weak to moderate earthquakes in the Sicily Channel have until now been either poorly located or left undetected. The number of seismic stations operated by various networks: Italy (INGV), Tunisia (TT), and Libya (LNSN) have now improved considerably, however most of the seismicity occurs offshore, in the central part of the Channel, away from the mainland stations. Seismic data availability from island stations across the Channel has been limited or had intermittent transmission hindering proper real-time earthquake monitoring and hypocentre relocation. In order to strengthen the seismic monitoring of the Sicily Channel, in particular the central parts of the Channel, the Seismic Monitoring and Research Unit (SMRU), University of Malta, has, in the last year, been installing a permanent seismic network across the Maltese archipelago: the Malta Seismic Network (ML). Furthermore the SMRU has upgraded its IT facilities to run a virtual regional seismic network composed of the stations on Pantelleria and Lampedusa, together with all the currently publicly available stations in the region. Selected distant seismic stations found elsewhere in the Mediterranean and across the globe have also been incorporated in the system in order to enhance the overall performance of the monitoring and to detect potentially damaging regional earthquakes. Data acquisition and processing of the seismic networks are run by SeisComP. The new installations are part of the project SIMIT (B1-2.19/11) funded by the Italia-Malta Operational Programme 2007-2013. The new system allows the SMRU to rapidly perform more accurate hypocentre locations in the region, and issue automatic SMS alert for potentially felt events in the Sicily Channel detected by the network and for strong earthquakes elsewhere. Within the SIMIT project, the alert system will include civil protection departments in Malta and Sicily. We present the recent developments of the real and virtual seismic network, and discuss the

  14. 3D Electromagnetic Particle-in-Cell simulations of the solar wind interaction with lunar magnetic anomalies

    NASA Astrophysics Data System (ADS)

    Deca, J.; Lapenta, G.; Divin, A. V.; Lembege, B.; Markidis, S.

    2013-12-01

    typically have gyroradii larger than the magnetic anomaly scale size) and magnetic field strength. The research leading to these results has received funding from the European Commission's Seventh Framework Programme (FP7/2007-2013) under the grant agreement SWIFF (project 2633430, swiff.eu). Cut along the dipole axis of the lunar anomaly, showing the electron density structure.

  15. Quality Aspects of a Marine Aggregate Deposit off the SE Euboea Island, Greece, for its Exploitation - Preliminary Results

    NASA Astrophysics Data System (ADS)

    Anastasatou, Marianthi; Kapsimalis, Vasilios; Stamatakis, Michael; Tsoutsia, Antonia; Poulos, Serafeim; Rousakis, Grigoris; Karditsa, Aikaterini; Petrakis, Stelios; Aspiotis, Konstantinos; Papavlasopoulou, Nafsika; Stamatakis, Giorgos

    2015-04-01

    % according to a semi-quantitative estimation) with minor trace minerals, such as albite and clay minerals. On the basis of the qualitative characteristics, sediments on the inner continental shelf of SE Euboea can be classified as siliceous and being considered appropriate for potential exploitation, that is related also to its quantitatively characteristics. The relatively shallow depths (<40 m) and the absence of any beach nearby together with the ordinary population of benthic community support such an extraction. Definitive decisions for the commercial interest of the specific deposit will be concluded after the accomplished quality characterization and the estimation of the proven and inferred reserves of the deposit. Acknowledgemts: This work is supported by the research program THALES-MARE (MIS: 375655) that is funded by the Operational Programme ''Education and lifelong learning, 2007-2013'' of the Ministry of Education and Religious Affairs, Culture and Sports.

  16. Role of melanocortin signalling in the preference for dietary macronutrients in human beings.

    PubMed

    van der Klaauw, Agatha; Keogh, Julia; Henning, Elana; Stephenson, Cheryl; Trowse, Victoria M; Fletcher, Paul; Farooqi, Sadaf

    2015-02-26

    Wolfe Health Neuroscience Fund, NeuroFAST consortium, which is funded by the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement no 245009. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. The development of topographic plateaus in an India-Asia-like collision zone using 3D numerical simulations

    NASA Astrophysics Data System (ADS)

    Pusok, Adina E.; Kaus, Boris; Popov, Anton

    2014-05-01

    . We also address the question of how large topographic plateaus, such as the Tibetan Plateau, can form in an integrated lithospheric and upper-mantle scale model. Acknowledgements: Funding was provided by the European Research Council under the European Community's Seventh Framework Program (FP7/2007-2013) / ERC Grant agreement #258830. Numerical computations have been performed on MOGON (ZDV Mainz computing center) and JUQUEEN (Jülich high-performance computing center).

  18. Insights from 3D numerical simulations on the dynamics of the India-Asia collision zone

    NASA Astrophysics Data System (ADS)

    Pusok, A. E.; Kaus, B.; Popov, A.

    2013-12-01

    /or indented into Asia. We investigate the way deep processes affect continental tectonics at convergent margins, addressing the role the continent subduction and indentation plays on the development of continental tectonics during convergence and we discuss the implications these offer for the Asian tectonics. Acknowledgements: Funding was provided by the European Research Council under the European Community's Seventh Framework Program (FP7/2007-2013) / ERC Grant agreement #258830. Numerical computations have been performed on MOGON (ZDV Mainz computing center) and JUQUEEN (Jülich high-performance computing center).

  19. Sensitivity of subtropical wetland CH4 flux predictions to inundation parameterizations: A case study over the southeastern U.S.

    NASA Astrophysics Data System (ADS)

    Resovsky, A.; Yang, Z. L.

    2015-12-01

    Methane (CH4) is an important greenhouse gas, and the predominant source of natural atmospheric CH4 globally is its production in wetland soils. Wetlands and marshes in the southeastern U.S. comprise over 40 million acres of land and thus represent a significant component of the global climate system. CH4 contributions from these and other subtropical systems remain difficult to quantify, however. Existing field measurements are lacking in both spatial and temporal coverage, inhibiting efforts to produce regional estimates through upscaling. Top-down constraints on emissions have been generated using satellite remote sensing retrievals of column CH4 (e.g., Frankenberg et al., 2005, 2008, Bergamaschi et al., 2007, 2013, Bloom et al., 2010, Wecht et al., 2014), but such approaches typically require preexisting emissions estimates to discern individual source contributions. Land Surface Models (LSMs) have the potential to produce realistic results, but such predictions rely on accurate representations of sub-grid scale processes responsible for emissions. Since net fluxes are governed by complex interactions between local environmental and biogeochemical factors including water table position, soil temperature, soil substrate availability and vegetation type, reliable flux simulations depend not only upon how such processes are resolved but how skillfully the land surface state itself is predicted by a given model. Here, we examine simulations using CLM4Me, a CH4 biogeochemistry model run within CESM, and compare results to recently compiled flux estimations from satellite remote sensing data. We then examine how seasonal CH4 flux simulations in CLM4Me are affected by alternative parameterizations of inundated land fraction. A global inundation dataset is calculated using DYPTOP, a newly-developed TOPMODEL implementation specifically designed to simulate the dynamics of wetland spatial distribution. We find evidence that DYPTOP may improve wetland CH4 flux predictions

  20. Object-Based Image Classification of Floating Ice Used as Habitat for Harbor Seals in a Tidewater Glacier Fjord in Alaska

    NASA Astrophysics Data System (ADS)

    McNabb, R. W.; Womble, J. N.; Prakash, A.; Gens, R.; Ver Hoef, J.

    2014-12-01

    Tidewater glaciers play an important role in many landscape and ecosystem processes in fjords, terminating in the sea and calving icebergs and discharging meltwater directly into the ocean. Tidewater glaciers provide floating ice for use as habitat for harbor seals (Phoca vitulina richardii) for resting, pupping, nursing, molting, and avoiding predators. Tidewater glaciers are found in high concentrations in Southeast and Southcentral Alaska; currently, many of these glaciers are retreating or have stabilized in a retracted state, raising questions about the future availability of ice in these fjords as habitat for seals. Our primary objective is to investigate the relationship between harbor seal distribution and ice availability at an advancing tidewater glacier in Johns Hopkins Inlet, Glacier Bay National Park, Alaska. To this end, we use a combination of visible and infrared aerial photographs, object-based image analysis (OBIA), and statistical modeling techniques. We have developed a workflow to automate the processing of the imagery and the classification of the fjordscape (e.g., individual icebergs, brash ice, and open water), providing quantitative information on ice coverage as well as properties not typically found in traditional pixel-based classification techniques, such as block angularity and seal density across the fjord. Reflectance variation in the red channel of the optical images has proven to be the most important first-level criterion to separate open water from floating ice. This first-level criterion works well in areas without dense brash ice, but tends to misclassify dense brash ice as single icebergs. Isolating these large misclassified regions and applying a higher reflectance threshold as a second-level criterion helps to isolate individual ice blocks surrounded by dense brash ice. We present classification results from surveys taken during June and August, 2007-2013, as well as preliminary results from statistical modeling of the

  1. An innovative multi-source approach for environmental monitoring of landfills

    NASA Astrophysics Data System (ADS)

    Manzo, Ciro; Mei, Alessandro; Paciucci, Lucia; Bassani, Cristiana

    2016-04-01

    nocturne thermal acquisitions. Moreover, a photogrammetric survey was achieved for 3d model production of the landfill to perform the correct estimation of the warning areas. This downscaling approach can be considered a performing methodology of investigation than the current classical methods, which require a great deal of work at local scale. Indeed the results revealed the effects of anthropic activities highlighting areas where in situ measurements could be advantageous to characterize the environmental conditions. The research activity is part of the POR CALABRIA FESR 2007/2013.

  2. Carbonaceous aerosols in the Western Mediterranean during summertime and their contribution to the aerosol optical properties at ground level: First results of the ChArMEx-ADRIMED 2013 intensive campaign in Corsica

    NASA Astrophysics Data System (ADS)

    Sciare, Jean; Dulac, Francois; Feron, Anais; Crenn, Vincent; Sarda Esteve, Roland; Baisnee, Dominique; Bonnaire, Nicolas; Hamonou, Eric; Mallet, Marc; Lambert, Dominique; Nicolas, Jose B.; Bourrianne, Thierry; Petit, Jean-Eudes; Favez, Olivier; Canonaco, Francesco; Prevot, Andre; Mocnik, Grisa; Drinovec, Luka; Marpillat, Alexandre; Serrie, Wilfrid

    2014-05-01

    in the Western Mediterranean Sea during summertime. Acknowledgements: Aerosol measurements performed at Cape Corsica Station were mainly funded by ANR, CNRS-INSU, ADEME, Collectivité Territoriale de Corse through EU-FEDER Operational program 2007-2013, CEA, METEO-FRANCE, MGR-KROP, AEROSOL D.O.O., ECOMESURE, and ENVICONTROL

  3. Statistical evaluation of the impact of shale gas activities on ozone pollution in North Texas.

    PubMed

    Ahmadi, Mahdi; John, Kuruvilla

    2015-12-01

    Over the past decade, substantial growth in shale gas exploration and production across the US has changed the country's energy outlook. Beyond its economic benefits, the negative impacts of shale gas development on air and water are less well known. In this study the relationship between shale gas activities and ground-level ozone pollution was statistically evaluated. The Dallas-Fort Worth (DFW) area in north-central Texas was selected as the study region. The Barnett Shale, which is one the most productive and fastest growing shale gas fields in the US, is located in the western half of DFW. Hourly meteorological and ozone data were acquired for fourteen years from monitoring stations established and operated by the Texas Commission on Environmental Quality (TCEQ). The area was divided into two regions, the shale gas region (SGR) and the non-shale gas (NSGR) region, according to the number of gas wells in close proximity to each monitoring site. The study period was also divided into 2000-2006 and 2007-2013 because the western half of DFW has experienced significant growth in shale gas activities since 2007. An evaluation of the raw ozone data showed that, while the overall trend in the ozone concentration was down over the entire region, the monitoring sites in the NSGR showed an additional reduction of 4% in the annual number of ozone exceedance days than those in the SGR. Directional analysis of ozone showed that the winds blowing from areas with high shale gas activities contributed to higher ozone downwind. KZ-filtering method and linear regression techniques were used to remove the effects of meteorological variations on ozone and to construct long-term and short-term meteorologically adjusted (M.A.) ozone time series. The mean value of all M.A. ozone components was 8% higher in the sites located within the SGR than in the NSGR. These findings may be useful for understanding the overall impact of shale gas activities on the local and regional ozone

  4. Evaluation of operational numerical weather predictions in relation to the prevailing synoptic conditions

    NASA Astrophysics Data System (ADS)

    Pytharoulis, Ioannis; Tegoulias, Ioannis; Karacostas, Theodore; Kotsopoulos, Stylianos; Kartsios, Stergios; Bampzelis, Dimitrios

    2015-04-01

    ) and Greek national funds, through the action "COOPERATION 2011: Partnerships of Production and Research Institutions in Focused Research and Technology Sectors" in the framework of the Operational Programme "Competitiveness and Entrepreneurship" and Regions in Transition (OPC II, NSRF 2007-2013).

  5. The ASTARTE Paleotsunami Deposits data base - a web-based reference for tsunami research around Europe

    NASA Astrophysics Data System (ADS)

    De Martini, Paolo Marco; Orefice, Simone; Patera, Antonio; Paris, Raphael; Terrinha, Pedro; Noiva, Joao; Hunt, James; Pantosti, Daniela

    2016-04-01

    capabilities of the portal. Any interested users will be able to access the online GIS resources through any Internet browser or specific apps that run on desktop machines, smartphones, or tablets and will be able to use the analytical tools, key tasks, and workflows of the service. The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement n° 603839 (Project ASTARTE - Assessment, Strategy and Risk Reduction for Tsunamis in Europe).

  6. Assessing the utility of a clinical prediction score regarding 30-day morbidity and mortality following metastatic spinal surgery: the New England Spinal Metastasis Score (NESMS).

    PubMed

    Schoenfeld, Andrew J; Le, Hai V; Marjoua, Youssra; Leonard, Dana A; Belmont, Philip J; Bono, Christopher M; Harris, Mitchel B

    2016-04-01

    The New England Spinal Metastasis Score (NESMS) was recently proposed to help predict 1-year survival following surgery for spinal metastases. Its ability to predict short-term outcomes, including 30-day morbidity, mortality, and hospital length of stay, has not been evaluated. Assess the capacity of NESMS to predict 30-day morbidity and mortality, as well as hospital length of stay, following surgery for spinal metastases. Validation study. All patients who had undergone spinal surgery with a history of metastatic spinal disease within the National Surgical Quality Improvement Program (NSQIP; 2007-2013). Mortality, complications, failure to rescue, and length of stay. Demographic, oncologic, laboratory, and surgical data were obtained from the NSQIP. All patients were assigned an NESMS score (0-3). The effect of the NESMS score on the outcomes of interest was assessed using multivariable logistic regression and negative binomial regression that controlled for confounders. Final model discrimination and calibration were assessed using the c-statistic and Hosmer-Lemeshow test, respectively. Internal validation was performed using a bootstrapping procedure. NSQIP data on 776 patients were included in this analysis. The 30-day mortality rate was 11% (N=87), and 51% of patients (N=395) sustained one or more complications. The final adjusted model demonstrated that the NESMS was a statistically significant predictor of 30-day mortality (p<.001), major systemic complications (p<.001), and failure to rescue (p=.03) following metastatic spinal surgery. Patients with an NESMS score of 3 had an 89% reduction in mortality (95% confidence interval [CI]: 0.04, 0.31), a 74% reduction in major systemic complications (95% CI: 0.11, 0.62), and an 88% reduction in failure to rescue (95% CI: 0.03, 0.47) as compared with those with a score of 0. The final model explained 71% of the variation in 30-day mortality. Findings were unchanged in the bootstrap analysis performed among 77

  7. Assessment of Satellite Albedos Using NASA-CAR Airborne Data

    NASA Astrophysics Data System (ADS)

    Kharbouche, S.; Charles, G.; Muller, J. P.

    2016-12-01

    , Landsat-7 and AVHRR, over vegetated, non-vegetated and ice-covered sites. We will show also how CAR data are arranged and how can be read and deployed. This work was supported by QA4ECV, a project of European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement no. 607405

  8. Analysis of Dark Slope Streaks on Mars based on Multitemporal HRSC Data

    NASA Astrophysics Data System (ADS)

    Schreiner, Björn; van Gasselt, Stephan; Jan-Peter, Muller

    2016-04-01

    Recurring slope lineae (RSL) on Mars are dark and narrow downhill oriented surface features found in equatorial regions (1) associated with water or hydrated salt flows (2). On the other hand there are Dark Slope Streaks which seem to be dry avalanches on dust covered slopes (3). The origin of both ist still under discussion. We found linear features in eastern Noctis Labyrinthus region (6°S, 265°E) with lengths of up to several kilometres and lateral extensions of 20-30 metres. As described by (4), RSL fade and recur in the same location over multiple Mars years. Similarily, Dark Slope Streaks form on at least annual to decade-long timescales (5). During 10 years of HRSC observation time (2005-2015) several linear features in Noctis Labyrinthus changed in visibility. Slope parameters and seasonal illumination conditions are investigated based on a digital elevation model derived from HRSC data. For large datasets a feature identification is presented which involves spatial filtering in conjunction with elevation data analysis. The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under iMars grant agreement n° 607379. (1) McEwen, A.S., et al. (2014): Recurring slope lineae in equatorial regions of Mars. Nat. Geosci 7: 53-58. (2) Ojha, L. et al. (2015): Spectral evidence for hydrated salts in recurring slope linear on Mars. Nat. Geosci, DOI:10.1038/NGEO2546. (3) Sullivan, R. et al. (2001). Mass Movement Slope Streaks Imaged by the Mars Orbiter Camera. J. Geophys. Res., 106(E10), 23,607-23,633. (4) McEwen, A.S., et al. (2011): Seasonal Flows on Warm Martian Slopes. Science, Vol. 333, Issue 6043, pp. 740-743. (5) Malin, M.C.; Edgett, K.S. (2001). Mars Global Surveyor Mars Orbiter Camera: Interplanetary cruise through primary mission. J. Geophys. Res., 106(E10), 23,429-23,570.

  9. Post-LIA glacier changes along a latitudinal transect in the Central Italian Alps

    NASA Astrophysics Data System (ADS)

    Scotti, R.; Brardinoni, F.; Crosta, G. B.

    2014-07-01

    The variability of glacier response to atmospheric temperature rise in different topo-climatic settings is still matter of debate. To address this question in the Central Italian Alps we compile a post-LIA (Little Ice Age) multitemporal glacier inventory (1860-1954-1990-2003-2007) along a latitudinal transect that originates north of the continental divide in the Livigno mountains, and extends south through the Disgrazia and Orobie ranges, encompassing continental-to-maritime climatic settings. In these sub-regions we examine area change of 111 glaciers. Overall, total glacierized area has declined from 34.1 to 10.1 km2, with a substantial increase in the number of small glaciers due to fragmentation. Average annual decrease (AAD) in glacier area has risen of about an order of magnitude from 1860-1990 (Livigno: 0.45; Orobie: 0.42; and Disgrazia: 0.39 % a-1) to 1990-2007 (Livigno: 3.08; Orobie: 2.44; and Disgrazia: 2.27 % a-1). This ranking changes when considering glaciers <0.5 km2 only (i.e., we remove the confounding caused by large glaciers in Disgrazia), so that post-1990 AAD follows the latitudinal gradient and Orobie glaciers stand out (Livigno: 4.07; Disgrazia: 3.57; and Orobie: 2.47 % a-1). More recent (2007-2013) field-based mass balances in three selected small glaciers confirm post-1990 trends showing consistent highest retreat in continental Livigno and minimal area loss in maritime Orobie, with Disgrazia displaying a transitional behaviour. We argue that the recent resilience of glaciers in Orobie is a consequence of their decoupling from synoptic atmospheric temperature trends. A decoupling that arises from the combination of local topographic configuration (i.e., deep, north-facing cirques) and high winter precipitation, which ensures high snow-avalanche supply, as well as high summer shading and sheltering. Our hypothesis is further supported by the lack of correlations between glacier change and glacier attributes in Orobie, as well by the higher

  10. Post-LIA glacier changes along a latitudinal transect in the Central Italian Alps

    NASA Astrophysics Data System (ADS)

    Scotti, R.; Brardinoni, F.; Crosta, G. B.

    2014-12-01

    The variability of glacier response to atmospheric temperature rise in different topo-climatic settings is still a matter of debate. To address this question in the Central Italian Alps, we compile a post-LIA (Little Ice Age) multitemporal glacier inventory (1860-1954-1990-2003-2007) along a latitudinal transect that originates north of the continental divide in the Livigno Mountains and extends south through the Disgrazia and Orobie ranges, encompassing continental-to-maritime climatic settings. In these sub-regions, we examine the area change of 111 glaciers. Overall, the total glacierized area has declined from 34.1 to 10.1 km2, with a substantial increase in the number of small glaciers due to fragmentation. The average annual decrease (AAD) in glacier area has risen by about 1 order of magnitude from 1860-1990 (Livigno: 0.45; Orobie: 0.42; and Disgrazia: 0.39 % a-1) to 1990-2007 (Livigno: 3.08; Orobie: 2.44; and Disgrazia: 2.27 % a-1). This ranking changes when considering glaciers smaller than 0.5 km2 only (i.e., we remove the confounding caused by large glaciers in Disgrazia), so that post-1990 AAD follows the latitudinal gradient and Orobie glaciers stand out (Livigno: 4.07; Disgrazia: 3.57; and Orobie: 2.47 % a-1). More recent (2007-2013) field-based mass balances in three selected small glaciers confirm post-1990 trends showing the consistently highest retreat in continental Livigno and minimal area loss in maritime Orobie, with Disgrazia displaying transitional behavior. We argue that the recent resilience of glaciers in Orobie is a consequence of their decoupling from synoptic atmospheric temperature trends, a decoupling that arises from the combination of local topographic configuration (i.e., deep, north-facing cirques) and high winter precipitation, which ensures high snow-avalanche supply, as well as high summer shading and sheltering. Our hypothesis is further supported by the lack of correlations between glacier change and glacier attributes in

  11. A critical analysis of the long-term impact (1936-2015) of grazing management on Land Degradation in a marginal, rural community of Southern Italy

    NASA Astrophysics Data System (ADS)

    Quaranta, Giovanni; Salvia, Rosanna; De Paola, Velia; Coluzzi, Rosa; Imbrenda, Vito; Simoniello, Tiziana

    2017-04-01

    situation where, in the search for economic viability (and social acceptance) many are left with the stark choice of intensification or abandonment. In doing so, the paper shows how, in some circumstances, the interplay of local and sovra-local forces produces an imbalance both in economic and environmental sense, ultimately meeting neither market demands nor ecosystem services. The paper ends with a recommendation for more targeted, evidence-based support for grazing farmland, along with better integration in the wider rural economy, if these farming practices are to survive into the future and if the EU is to meet its 2020 targets. The research was partially supported by funding from the European Union's Seventh Framework Programme (FP7/2007-2013), grant agreement 283068 (CASCADE).

  12. Variation of Arctic's Sea-ice Albedo between 2000 and 2016 by fusion of MISR and MODIS data

    NASA Astrophysics Data System (ADS)

    Muller, Jan-Peter; Kharbouche, Said

    2017-04-01

    Programme (FP7/2007-2013) under grant agreement no. 607405.

  13. Using GIS techniques to detect the impact of territorial evolution on producing natural hazard in Northern Romania, commune Vorniceni

    NASA Astrophysics Data System (ADS)

    Gălbău, Ionela

    2015-04-01

    paper has been financially supported within the project entitled "SOCERT. Knowledge society, dynamism through research", contractnumber POSDRU/159/1.5/S/132406. This project is co-financed by European Social Fund through Sectoral Operational Programme for Human Resources Development 2007-2013. Investing in people!"

  14. Fuel type characterization and potential fire behavior estimation in Sardinia and Corsica islands

    NASA Astrophysics Data System (ADS)

    Bacciu, V.; Pellizzaro, G.; Santoni, P.; Arca, B.; Ventura, A.; Salis, M.; Barboni, T.; Leroy, V.; Cancellieri, D.; Leoni, E.; Ferrat, L.; Perez, Y.; Duce, P.; Spano, D.

    2012-04-01

    BEHAVE fire behavior prediction system (Andrews, 1989) and experimental fuel data. Fire behavior was simulated by setting different weather scenarios representing the most frequent summer meteorological conditions. The simulation outputs (fireline intensity, rate of spread, flame length) were then analyzed for clustering the different fuel types in relation to their potential fire behavior. The results of this analysis can be used to produce fire behavior fuel maps that are important tools in evaluating fire hazard and risk for land management planning, locating and rating fuel treatments, and aiding in environmental assessments and fire danger programs modeling. This work is supported by FUME Project FP7-ENV-2009-1, Grant Agreement Number 243888 and Proterina-C Project, EU Italia-Francia Marittimo 2007-2013 Programme.

  15. Great Danube flood peak of the late medieval - early modern transition: the 1470s-1520s

    NASA Astrophysics Data System (ADS)

    Kiss, Andrea

    2016-04-01

    As a consequence of very detailed contemporary documentation, namely legal-administrative documentation (charters) and the annual (or daily) information available in the Bratislava accounts (mainly bridgemasters' accounts), a relatively detailed picture of a massive flood peak can be detected in the Carpathian Basin documentation concerning the decades of the late 15th and early 16th centuries. These decades are one of the most important period in the millennial flood history of the Danube in this area: both concerning the number of individual flood events and regarding the information on multiannual problems. Moreover, archaeological evidence, for example the flood sediment layers in Visegrád and also the damages, structural and elevation changes of renovated buildings in Buda or along the Upper-Danube, provide similar examples of multiannual flood-related problems. Moreover, clear flood peaks can be also detected at this time on the Austrian sections of the Danube, but especially on its Eastern Alpine tributaries, centred around the 1480s and the greatest flood events of 1501, and also partly of 1503 and 1508 (best documented for the Traun at Wels: see Rohr 2007, 2013). In the poster presentation on the one hand a general overview of the documented flood events and multiannual flood-related information - based on documentary and archaeological evidence -, occurred in the Carpathian Basin are presented regarding frequency, magnitude (3-scaled classification) and seasonality information (when available). On the other hand, differences in flood frequencies, flood types and seasonality is also separately discussed on an annual and decadal scale: while, for example, in the drought-affected 1470s were characterised by ice jam floods, the great flood peak of the 1480s were both rich in ice jams and summer-flood events (with a peak in 1485 with 4 great floods). The decade of the 1500s was mainly influenced by the 1501 "deluge" and further two great flood events (and

  16. Application and Validation of a GIS Model for Local Tsunami Vulnerability and Mortality Risk Analysis

    NASA Astrophysics Data System (ADS)

    Harbitz, C. B.; Frauenfelder, R.; Kaiser, G.; Glimsdal, S.; Sverdrup-thygeson, K.; Løvholt, F.; Gruenburg, L.; Mc Adoo, B. G.

    2015-12-01

    Prevention Structures fOr enhanced tsunami DIsaster resilience http://www.ngi.no/en/Project-pages/RAPSODI/), and from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement n° 603839 (Project ASTARTE - Assessment, STrategy And Risk reduction for Tsunamis in Europe http://www.astarte-project.eu/).

  17. The observation of Martian dune migration using very high resolution image analysis and photogrammetric data processing

    NASA Astrophysics Data System (ADS)

    Kim, Jungrack; Yun, Hyewon; Kim, Younghwi; Baik, Hyunseob

    2016-04-01

    can be compared with the numerical simulation. ACKNOWLEDGEMENTS: The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under iMars grant agreement Nr. 607379.

  18. Diurnal variations in water vapor over Central and South America

    NASA Astrophysics Data System (ADS)

    Meza, Amalia; Mendoza, Luciano; Clara, Bianchi

    2017-04-01

    Diurnal variations in atmospheric integrated water vapor (IWV) are studied employing IWV estimates, with a 30 minutes sampling rate, derived from Global Navigation Satellite Systems (GNSS) observations during the period 2007-2013. The analysis was performed in 70 GNSS tracking sites (GPS + GLONASS) belonging to Central and South America, which have more than 5 years of data. The selected area involves different climate types, from polar to tropical, and diverse relieves, therefore the patterns of IWV diurnal variations are very different for each station. There are many processes that could induce diurnal variations in atmospheric water vapor (Dai et al, 1999 a,b), the most relevant causes are: surface evapotranspiration, atmospheric large-scale vertical motion, atmospheric low-level moisture convergence and precipitation and vertical mixing (which affects the vertical distribution of water vapor but does not affect the IWV). Firstly, our work study the main characteristics of the IWV diurnal cycle (and for surface temperature, T) obtained for all stations together, using Principal Component Analysis (PCA). First and second PCA modes highlight the global main behaviors of IWV variability for all stations. The first mode on IWV represent the 70% of the variability and could be related to the surface evapotranspiration, while the second mode (27 % of the variability) is practically in counter phase to T variability (its first mode represent the 97% of the variability), therefore this mode could be related to breeze regime. Then, every station is separately analyzed and seasonal and local variations (relative to the relives) are detected, these results spotlight, among other characteristics, the sea and mountain breeze regime. This presentation shows the first analysis of IWV diurnal cycle performed over Central and South America and another original characteristic is PCA technique employed to infer the results. Reference: Dai, A., K. E. Trenberth, and T. R. Karl

  19. Examining the Interaction Between the Sea Breeze and the Timing of the Daily Maximum Temperature in Summer Season over the Mediterranean Region of Turkey

    NASA Astrophysics Data System (ADS)

    Tozcu, Sesil; Önol, Barış; Batıbeniz, Fulden

    2016-04-01

    In this study, sea-breeze and its effects on timing and severity of maximum temperature have been analyzed over the Mediterranean basin of Turkey for the period of the 2007-2013 summer season. The calculation of the extreme climate index TX35 (days of Tmax > 35 ° C) by using the station data indicated that TX35 is less than expected over southern coasts of Turkey. Therefore, the purpose of this study is to define days of extreme temperatures in terms of the sea-breeze phenomenon over the coastal region. Sub-daily (hourly) observations for wind speed, direction frequencies and temperature from the selected meteorological stations (totally 21) in Mugla, Antalya, Mersin, Adana and Hatay Provinces have been analyzed. Two of the five stations are located inland for Adana province. The sea breeze is observed in the coastal stations and the maximum temperature occurred before 13:00. However, the maximum temperature is observed one hour later at 14:00 for inland stations in same province and it exceeds 35 ° C. We also examined the similar characteristics for the coastal and inland stations of Mugla province. In addition, the maximum temperature from daily high-resolution gridded data (E-OBS) and daily 10-m surface wind from ERA-Interim dataset have investigated to define correlation between the wind speed-direction and maximum temperature. Daily analysis present that the days of the highest maximum temperature observed in each summer months coherent the weak (or no) sea-breeze. The monthly means of summer months also indicate that the wind vectors at 12:00 GMT (3 pm at local) explains clearly the sea-breeze over the coast of Mediterranean basin, since prevailing wind is mainly from the southwest, meanwhile the surface wind over the Mediterranean Sea is mostly from the west. Consequently, the sea-breeze causes that the maximum temperature does not exceed 35 ° C after 12:00 for central provinces of the Mediterranean region of Turkey.

  20. Assessing Soil Salinity with the use of WorldView-2 Hyperspectral Images in Timpaki, Crete

    NASA Astrophysics Data System (ADS)

    Alexakis, Dimitrios D.; Daliakopoulos, Ioannis N.; Panagea, Ioanna S.; Tsanis, Ioannis K.

    2016-04-01

    broad range of ECe ranging from 0.84 dS m-1 in non-cultivated fields to 199.91 dS m-1 at the coastal salt marsh Katalyki. Results show that WorldView-2 and Landsat 8 images have a potential for effective topsoil salinity mapping when adequately calibrated. Keywords: soil salinity; remote sensing; WorldView-2; Timpaki Crete The research leading to these results has received funding from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement n° 603498 (RECARE).

  1. Mineralogy and geochemistry of trace and Rare Earth Element from the Manaila massive sulphide deposit (Eastern Carpathians, Romania)

    NASA Astrophysics Data System (ADS)

    Moldoveanu, S.; Iancu, O. G.; Kasper, H. U.

    2012-04-01

    ) behavior of these elements in pure silicate melts. The REE patterns of the ores are highly variable and do not appear to be related to the mineral compositions. This feature may reflect contributions from several factors involved in fluid formation, ore mineral deposition and post-depositional processes. The lack of a relation between major mineral composition and REE patterns suggests complex REE fractionation processes during the ore formation. This work was supported by the European Social Fund in Romania, under the responsibility of the Managing Authority for the Sectoral Operational Programme for Human Resources Development 2007-2013 (grant POSDRU/88/1.5/S/47646).

  2. PRo3D®: A Tool for High Resolution Rendering and Geological Analysis of Martian Rover-Derived Digital Outcrop Models.

    NASA Astrophysics Data System (ADS)

    Gupta, S.; Barnes, R.; Ortner, T.; Huber, B.; Paar, G.; Muller, J. P.; Giordano, M.; Willner, K.; Traxler, C.; Juhart, K.; Fritz, L.; Hesina, G.; Tasdelen, E.

    2015-12-01

    exploitation of vision data from future missions, such as the 2018 ExoMars Rover and the NASA 2020 mission. The research leading to these results has received funding from the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement n° 312377 PRoViDE.

  3. Survey of the spectral properties of turbulence in the solar wind, the magnetospheres of Venus and Earth, at solar minimum and maximum

    NASA Astrophysics Data System (ADS)

    Echim, Marius M.

    2014-05-01

    and maximum of the solar cycle we also analyze the spectral similarities and differences between fast and slow wind turbulence. We emphasize the importance of our data survey and analysis in the context of understanding the solar wind turbulence, the exploitation of data bases and as a first step towards developing a (virtual) laboratory for studying solar system plasma turbulence. Research supported by the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement no 313038/STORM, and a grant of the Romanian Ministry of National Education, CNCS - UEFISCDI, project number PN-II-ID-PCE-2012-4-0418.

  4. Seasonal variability of dust in the eastern Mediterranean (Athens, Greece), through lidar measurements in the frame of EARLINET (2002-2012)

    NASA Astrophysics Data System (ADS)

    Kokkalis, Panos; Papayannis, Alex; Tsaknakis, George; Mamouri, RodElise; Argyrouli, Athina

    2013-04-01

    water vapor mixing ratio, from about 700 m up to 10000 m, with high temporal (< 5 min.) and spatial (7.5 m) resolution. Acknowledgements: This research has been co-financed by the European Union (European Social Fund - ESF) and Greek national funds through the Operational Program "Education and Lifelong Learning" of the National Strategic Reference Framework (NSRF) - Research Funding Program: Heracleitus II - Investing in knowledge society through the European Social Fund. This research was also financially supported by ITARS (www.itars.net), European Union Seventh Framework Programme (FP7/2007-2013): People, ITN Marie Curie Actions Programme (2012-2016) under grant agreement no 289923.

  5. Decreasing loco-regional recurrence for oral cavity cancer with total Mohs margins technique.

    PubMed

    Bergeron, Mathieu; Gauthier, Pierre; Audet, Nathalie

    2016-12-01

    The conventional technique for cancer resection margin analysis studies only 0.1% of the surgical margins. Complete frozen section margins - also known as Mohs margins - allows for analysis of 100% of the surgical margins. The objective of our study is to compare oral cavity cancer loco-regional recurrence rates when treated by total frozen sections technique (Total Mohs margins) versus conventional margins. We conducted a multicenter retrospective cohort chart review. Loco-regional oral cancer recurrence rates were compared between patients treated with total Mohs margins (2007-2013) and patients treated with conventional margins techniques (2002-2007). After applying inclusion criteria, a total of 60 patients treated by total Mohs margins and 57 patients with conventional margins were identified. Patients had similar baseline cancer stages, pathological types, past head and neck cancers and comorbidities (all p > 0.05). One-year recurrence rate was lower (10.0% vs 21.1%, p = 0.019) in favor of Mohs total margins and stayed significantly lower at 5 years of follow-up. When adjusted for T grade with N0 disease, Mohs technique was still beneficial in loco-regional recurrence for Tis-T4N0 up to 2 years (10.5% vs 25.7%, z-score 1.849, p = 0.032). The Number Needed to Treat at 2 years of follow-up for this subgroup of patients (Tis-T4N0) is 6.6. Margins had to be retaken more often intra-operatively in Mohs technique (68.3% vs 12.3%, p < 0.0001), mainly for positive deep margins (48.6% of all margins, p = 0.028). Duration of surgery was not increased with Mohs vs conventional technique (380 min vs 475 min respectively, p = 0.025). Mohs total margins may result in a significant reduction in cancer recurrence rate at 5 years compare to conventional surgery. Moreover, duration of surgery was not increased when using Mohs technique when judiciously performed.

  6. Experimental evidence of condensation-driven airflow

    NASA Astrophysics Data System (ADS)

    Bunyard, P.; Hodnett, M.; Poveda, G.; Burgos Salcedo, J. D.; Peña, C.

    2015-10-01

    The dominant "convection" model of atmospheric circulation is based on the premise that hot air expands and rises, to be replaced by colder air, thereby creating horizontal surface winds. A recent theory put forward by Makarieva and Gorshkov (2007, 2013) maintains that the primary motive force of atmospheric circulation derives from the intense condensation and sharp pressure reduction that is associated with regions where a high rate of evapotranspiration from natural closed-canopy forests provides the "fuel" for cloud formation. The net result of the "biotic pump" theory is that moist air flows from ocean to land, drawn in by the pressure changes associated with a high rate of condensation. To test the physics underpinning the biotic pump theory, namely that condensation of water vapour, at a sufficiently high rate, results in an uni-directional airflow, a 5 m tall experimental apparatus was designed and built, in which a 20 m3 body of atmospheric air is enclosed inside an annular 14 m long space (a "square donut") around which it can circulate freely, allowing for rotary air flows. One vertical side of the apparatus contains some 17 m of copper refrigeration coils, which cause condensation. The apparatus contains a series of sensors measuring temperature, humidity and barometric pressure every five seconds, and air flow every second. The laws of Newtonian physics are used in calculating the rate of condensation inside the apparatus. The results of more than one hundred experiments show a highly significant correlation, with r2 > 0.9, of airflow and the rate of condensation. The rotary air flows created appear to be consistent both in direction and velocity with the biotic pump hypothesis, the critical factor being the rate change in the partial pressure of water vapour in the enclosed body of atmospheric air. Air density changes, in terms of kinetic energy, are found to be orders of magnitude smaller than the kinetic energy of partial pressure change. The

  7. Influence of biochar on the enantioselective behavior of the chiral fungicide metalaxyl in soil

    NASA Astrophysics Data System (ADS)

    Gámiz, Beatriz; Pignatello, Joseph J.; Hermosín, María Carmen; Cox, Lucía; Celis, Rafael

    2015-04-01

    columns was recovered in leachates, in contrast to significantly higher percentages leachedin unamended soil, being the process more enantioselective in the latter case. Finally, total recoveries of both enantiomers were greater for BC-amended soil columns than for unamended soil columns, indicating reduced degradation in BC- amended soil. Our findings illustrated the ability of biochar to modify the enantioselectivity behavior of metalaxyl in soil by its high sorption capacity. BC could contribute to reduce the current agronomic doses used for chiral pesticides to deplete the contamination problems associated with their use, and also to act as an immobilizing amendment in soil remediation strategies. Acknowledgments: MINECO (AGL2011-23779), FACCE-JPI (Designchar4food), JA (AGR-264) and FEDER-FSE (OP 2007-2013).

  8. Assesment of CALIPSO's level 3 climatological product

    NASA Astrophysics Data System (ADS)

    Papagiannopoulos, Nikolaos; Mona, Lucia; Pappalardo, Gelsomina

    2015-04-01

    estimates that can be used to create more reliable model forecasts based on CALIPSO data. Moreover, the presented work can contribute to current and future studies that use space-based lidar data. Acknowledgments: The financial support for EARLINET provided by the European Union under grant RICA 025991 within the framework of the Sixth Framework Programme is gratefully acknowledged. Since 2011 EARLINET has been integrated in the ACTRIS Research Infrastructure Project supported by the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement no. 262254.

  9. Analysis of Dark Slope Streaks on Mars based on Multitemporal Imagery and Digital Elevation Model derived from HRSC Data

    NASA Astrophysics Data System (ADS)

    Schreiner, Bjoern Peter; Walter, Sebastian; Muller, Jan-Peter; Sidiropoulos, Panagiotis

    2016-10-01

    Recurring slope lineae (RSL) on Mars are dark and narrow downhill oriented surface features found in equatorial regions (1) associated with water or hydrated salt flows (2). On the other hand there are Dark Slope Streaks which seem to be dry avalanches on dust covered slopes (3). The origin of both ist still under discussion. We found linear features in eastern Noctis Labyrinthus region (6°S, 265°E) with lengths of up to several kilometres and lateral extensions of 20-30 metres. RSL fade andrecur in the same location over multiple Mars years (4). Similarily, Dark Slope Streaks form on at least annual to decade-long timescales (5). During 10 years of HRSC observation time (2005-2015) several linear features in Noctis Labyrinthus changed in visibility. Slopeparameters and seasonal illumination conditions are investigated based ona DTM derived from HRSC data. Also particle flow along streaks has been modelled. Feature and change identification is presented involving spatial filtering and DTM analysis.The research leading to these results has received funding from theEuropean Union's Seventh Framework Programme (FP7/2007-2013) under iMars grant agreement n° 607379.(1) McEwen, A.S., et al. (2014): Recurring slope lineae in equatorialregions of Mars. Nat. Geosci 7: 53-58.(2) Ojha, L. et al. (2015): Spectral evidence for hydrated salts inrecurring slope linear on Mars. Nat. Geosci, DOI:10.1038/NGEO2 546.(3) Sullivan, R. et al. (2001). Mass Movement Slope Streaks Imaged by theMars Orbiter Camera. J. Geophys. Res., 106(E10), 23,607-23,633.(4) McEwen, A.S., et al. (2011): Seasonal Flows on Warm Martian Slopes.Science, Vol. 333, Issue 6043, pp. 740-743.(5) Malin, M.C.; Edgett, K.S. (2001). Mars Global Surveyor Mars OrbiterCamera: Interplanetary cruise through primary mission. J. Geophys. Res., 106(E10), 23,429-23,570.

  10. Validation and Performance Comparison of Numerical Codes for Tsunami Inundation

    NASA Astrophysics Data System (ADS)

    Velioglu, D.; Kian, R.; Yalciner, A. C.; Zaytsev, A.

    2015-12-01

    results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement No 603839 (Project ASTARTE - Assessment, Strategy and Risk Reduction for Tsunamis in Europe)

  11. What Can Spectral Properties of Martian Surface and Snc Can Tell Us about the Martian Crust Composition and Evolution

    NASA Astrophysics Data System (ADS)

    Ody, A.; Poulet, F.; Baratoux, D.; Quantin, C.; Bibring, J. P.

    2014-12-01

    et al., [2001], Chronology and Evolution of Mars, pp. 105-164. [9] Balta and McSween, 2013, Geology,v. 41, p. 1115-1118. Acknowledgment:The research leading to these results has received funding from the European Research Council under the European Union's Seventh Framework Program (FP7/2007-2013)/ERC Grant agreement n°280168 .

  12. A methodology for system-of-systems design in support of the engineering team

    NASA Astrophysics Data System (ADS)

    Ridolfi, G.; Mooij, E.; Cardile, D.; Corpino, S.; Ferrari, G.

    2012-04-01

    project co-financed by Piedmont Region and firms and universities of the Piedmont Aerospace District in the ambit of the P.O.R-F.E.S.R. 2007-2013 program.

  13. Mapping the isotopic signature of methane in South-Eastern Spain: complementing biogeochemical long-term research with short term observations

    NASA Astrophysics Data System (ADS)

    Àgueda, Alba; Morguí, Josep Anton; Vazquez Garcia, Eusebi; Curcoll, Roger; Lowry, David; Fisher, Rebecca E.; Nisbet, Euan G.

    2016-04-01

    will be helpful in the validation of transport models. *Corresponding author: Josep Anton Morguí - josep-anton.morgui@ic3.cat "The research leading to these results has received funding from the European Community's Seventh Framework Programme (FP7/2007-2013) in the InGOS project under grant agreement n° 284274''

  14. Automated Detection of Opaque Volcanic Plumes in Polar Satellite Data

    NASA Astrophysics Data System (ADS)

    Dehn, J.; Webley, P.

    2013-12-01

    Response to an explosive volcanic eruption is time sensitive, so automated eruption detection techniques are essential to minimize alert times after an event. Automated detection of volcanic ash plumes in satellite imagery is usually done using a variant of the split-window or reverse-absorption method. This method is often effective but requires among other things that an ash plume be translucent to allow thermal radiation to pass through it. In the critical first hour or two of an eruption, plumes are most often opaque, and therefore cannot be detected by this method. It has been shown that an emergent plume appears as a sudden cold cloud over a volcano where a weather system should not appear, and this has been applied to geostationary data that is acquired every 15 to 30 minutes and will be an integral part of the upcoming geostationary mission, GOES-R. In this study this concept is used on time sequential polar orbiting satellite data to detect emergent plumes. This augments geostationary data, and may detect smaller plumes at higher latitudes where geostationary data suffers from poorer spatial resolution. A series of weighted credits and demerits are used to determine the presence of an anomalously cold cloud over a volcano in time sequential advanced very high resolution radiometer (AVHRR) data. Parameters such as coldest thermal infrared temperature, time between images, ratio of cold to background temperature, and temperature trend are assigned a weighted value and a threshold used to determine the presence of an anomalous cloud. The weighting and threshold is unique for each volcano due to weather conditions and satellite coverage. Using the 20 year archive of eruptions in the North Pacific at the Geophysical Institute of the University of Alaska Fairbanks, explosive eruptions were evaluated at Karmsky Volcano (1996), Pavlof volcano (1996, 2007, 2013), Cleveland Volcano (1994, 2001, 2008), Shishaldin Volcano (1999), Augustine Volcano (2006), Fourpeaked

  15. CCN in the marine environment: Results from two intensive measurement campaigns - The Eastern North Atlantic (Mace Head) and The Southern Ocean (PEGASO cruise)

    NASA Astrophysics Data System (ADS)

    Ovadnevaite, Jurgita; Fossum, Kirsten; Ceburnis, Darius; Dall'Osto, Manuel; Simo, Rafel; O'Dowd, Colin

    2016-04-01

    Marine aerosol occurring in cloud condensation nucleus (CCN) sizes suggest that it may contribute notably to the CCN population [1, 2], but further cloud droplet number concentration would strongly depend on the ambient (cloud) conditions, such as available water content, supersaturation and competition between the CCN of different composition [3]. Since the global importance of marine aerosol particles to the cloud formation was postulated several decades ago [4], it has progressed from the evaluation of the nss-sulphate and sea salt effects to an acknowledgement of the significant role of organic aerosol [5]. It was demonstrated that primary marine organics, despite its hydrophobic nature, can possess the high CCN activation efficiency, resulting in the efficient cloud formation [6]. Results from two intensive measurement campaigns in The Eastern North Atlantic (Mace Head) and The Southern Ocean (PEGASO cruise) is presented here with the main focus on ssCCN dependence on aerosol chemical composition and, especially, origin and sources of marine organic. We investigate the activation of sea spray composed of the sea salt and externally mixed with nss-sulphate as well as the sea spray highly enriched in organics, stressing the importance of the latter to the formation of the cloud droplets. We also explore the suitability of existing theories to explain the marine aerosol activation to CCN. Acknowledgments The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) project BACCHUS under grant agreement n° 603445; Spanish Ministry of Economy and Competitiveness (MINECO) as part of the PEGASO (Ref.: CTM2012-37615) and BIO-NUC (Ref.: CGL2013-49020-R); HEA-PRTLI4;EC ACTRIS. [1] Meskhidze & Nenes (2006) Science 314, 1419-1423. [2] Sorooshian et al. (2009) Global Biogeochemical Cycles 23, GB4007. [3] O'Dowd et al. (1999) Quarterly Journal of the Royal Meteorological Society 125, 1295-1313. [4] Charlson

  16. The national cost of asthma among school-aged children in the United States.

    PubMed

    Sullivan, Patrick W; Ghushchyan, Vahram; Navaratnam, Prakash; Friedman, Howard S; Kavati, Abhishek; Ortiz, Benjamin; Lanier, Bob

    2017-09-01

    Recent research has quantified the national health care resource use (HCRU) and health care expenditure (HCE) burden associated with adult asthma; however, estimates specific to school-aged children are more than 2 decades old. To estimate the national HCRU and HCEs attributable to asthma among school-aged children in the United States. This was a cross-sectional retrospective analysis of school-aged children (aged 6-17 years) in the nationally representative 2007-2013 Medical Expenditure Panel Survey. All-cause HCRU and HCEs of school-aged children with asthma were compared with school-aged children without asthma, controlling for sociodemographics and comorbidities. HCRU encounters included emergency department (ED) and outpatient visits, hospitalizations, and prescriptions. Expenditures included total, medical, ED, inpatient, outpatient, and pharmacy. Negative binomial regression analyses were used for HCRU and Heckman selection with logarithmic transformation, and smearing retransformation was used for HCEs. There were 44,320 school-aged children of whom 5,890 had asthma. Children with asthma incurred a higher rate of all-cause annual ED visits (incidence rate ratio [IRR], 1.5; P < .001), hospitalizations (IRR, 1.4; P < .05), outpatient visits (IRR, 1.4; P < .001), and prescription drugs (IRR, 3.3; P < .001) compared with school-aged children without asthma. They incurred US$847 (2015 dollars) more annually in all-cause expenditures (P < .001). Private insurance and Medicaid paid the largest share of expenditures. Pharmacy and outpatient costs represented the largest proportion of total expenditures. On the basis of the nationally representative Medical Expenditure Panel Survey sample weights from 2013, the total annual HCEs attributable to asthma for school-aged children in the United States was US$5.92 billion (2015 dollars). Childhood asthma continues to represent a prevalent and significant clinical and economic burden in the United States. More aggressive

  17. Influence of Body Mass Index and Albumin on Perioperative Morbidity and Clinical Outcomes in Resected Pancreatic Adenocarcinoma.

    PubMed

    Hendifar, Andrew; Osipov, Arsen; Khanuja, Jasleen; Nissen, Nicholas; Naziri, Jason; Yang, Wensha; Li, Quanlin; Tuli, Richard

    2016-01-01

    Obesity is a known risk factor for PDA and recent reports suggest obesity has a negative impact on clinical outcomes in patients with PDA. Pretreatment body mass index (BMI) and serum albumin (SA) have been shown to be associated with worse overall survival in patients with advanced and metastatic PDA. However, minimal data exists on the impact of BMI and SA on perioperative and long-term clinical outcomes in patients with early-stage resected PDA. Herein, we report on the impact of these variables on perioperative clinical outcomes, overall survival (OS) and disease free survival (DFS) in patients with resected PDA. With IRB approval, we evaluated 1,545 patients with PDA treated at a single institution from 2007-2013 and identified 106 patients who underwent upfront resection with curative intent. BMI and SA were calculated preoperatively and at the time of last clinical evaluation. Influence of preoperative BMI, SA, change in either variable, and influence of other clinical and pathologic variables on perioperative morbidity and mortality was assessed. The impact of these variables on DFS and OS was assessed with cox regression modeling and ANOVA. Actuarial estimates for DFS and OS were calculated using Kaplan-Meier methods. Median follow up time was 16 months (3-89). Mean age was 68 years. Median survival was 14 months (3-65) and median time to recurrence was 11 months (1-79). Length of hospital stay was associated with BMI (p = .023), change in BMI (p = .003) and SA (p = .004). Post-operative transfusion rate was associated with SA (p = .021). There was a strong correlation between BMI change and positive margin (p = .04) and lymph node status (p = .01). On multivariate analysis, change in SA (p = .03) and node positivity (p = .008) were associated with decreased DFS. Additionally, preoperative SA (p = .023), node positivity (p = .026) and poor differentiation (p = .045) were associated with worse OS on multivariate analysis. Low preoperative SA was associated

  18. Acquisition, capitalization, modeling and sharing of volcanic and seismic monitoring data at La Réunion Island

    NASA Astrophysics Data System (ADS)

    Boissier, Patrice; Di Muro, Andrea; Henriette, Laura; Rivière, Audrey; Roult, Geneviève; Agrinier, Pierre; Beauducel, François; Davoine, Paule-Annick; Dyon, Joël; Ferrazzini, Valérie; Kowalski, Philippe; Lemarchand, Arnaud; Nercessian, Alexandre; Peltier, Aline; Shapiro, Nikolai; Staudacher, Thomas; Villeneuve, Nicolas

    2014-05-01

    Piton de la Fournaise is one of the most active volcano in the world with an average of one eruption every 9 months, and rest periods of short duration (only 2 periods exceeded 5 years during the last 50 years). Even if 97 percent of the recent volcanic activity took place within the uninhabited Enclos Fouque caldera; only 3 eruptions occurred outside of the caldera, threatening inhabited areas. The distal 1977 eruption (NE rift), the lave flows of which passed through Piton Sainte-Rose village, destroying houses and forced the evacuation of part of the population, triggered an awareness of volcanic risk at Piton de la Fournaise and led to the creation of the Piton de la Fournaise Volcano Observatory (OVPF - IPGP) in 1979. During thirty-five years, the continuous monitoring networks (geophysical and geochemical), measurements campaigns and phenomenological observation (e.g. imaging and films in the visible and infrared) have built an extraordinary amount of heterogeneous data in terms of format (digital and analog) and storage supports (paper, magnetic tape, floppy disk, etc.). With the aim to structure and distribute the data acquired since its establishment the OVPF conceived an innovative project for "Acquisition, capitalization, modeling and sharing of volcanic and seismic monitoring data at La Reunion Island". The project is funded by the European Regional Development Fund - Convergence (2007-2013) and supported by the local government (Region Reunion). The project is structured around two main parts : - Action 1: acquisition, digitizing and data backup, - Action 2: development of an Information System. On one hand, the project has the ultimate goal to facilitate the distribution of high quality data and long time series to the largest number of beneficiaries of the local, national and international scientific community and of the public and private sectors through IPGP Internet portals (IPGP Data Center and VOLOBSIS). On the other hand, the information system

  19. Drones application on snow and ice surveys in alpine areas

    NASA Astrophysics Data System (ADS)

    La Rocca, Leonardo; Bonetti, Luigi; Fioletti, Matteo; Peretti, Giovanni

    2015-04-01

    First results from Climate change are now clear in Europe, and in Italy in particular, with the natural disasters that damaged irreparably the territory and the habitat due to extreme meteorological events. The Directive 2007/60/EC highlight that an "effective natural hazards prevention and mitigation that requires coordination between Member States above all on natural hazards prevention" is necessary. A climate change adaptation strategy is identified on the basis of the guidelines of the European Community program 2007-2013. Following the directives provided in the financial instrument for civil protection "Union Civil Protection Mechanism" under Decision No. 1313/2013 / EU of the European Parliament and Council, a cross-cutting approach that takes into account a large number of implementation tools of EU policies is proposed as climate change adaptation strategy. In last 7 years a network of trans-Alpine area's authorities was created between Italy and Switzerland to define an adaptive strategy on climate change effects on natural enviroment based on non structural remedies. The Interreg IT - CH STRADA Project (STRategie di ADAttamento al cambiamento climatico) was born to join all the non structural remedies to climate change effects caused by snow and avalanches, on mountain sources, extreme hydrological events and to manage all transnational hydrological resources, involving all stakeholders from Italy and Switzerland. The STRADA project involved all civil protection authorities and all research centers in charge of snow, hydrology end civil protection. The Snow - meteorological center of the Regional Agency for Environment Protection (CNM of ARPA Lombardia) and the Civil Protection of Lombardy Region created a research team to develop tools for avalanche prediction and to observe and predict snow cover on Alpine area. With this aim a lot of aerial photo using Drone as been performed in unusual landscape. Results of all surveys were really interesting on a

  20. Quantifying the vulnerability of carbon stocks and fluxes in six semi-arid biomes in the Southwestern US to the severe 2011-2013 drought (Invited)

    NASA Astrophysics Data System (ADS)

    Litvak, M. E.; Krofcheck, D.; Hilton, T. W.; Fox, A. M.

    2013-12-01

    The magnitude of carbon fluxes through arid and semi-arid ecosystems is considered modest, but integrated over the ~40% of the global land surface covered by these ecosystems, the total carbon stored is almost twice that in temperate forest ecosystems. Climatic extremes are typical in the Southwestern U.S, and the frequency of extreme temperature and precipitation events (both drought and large storms) in this region is predicted to increase in the next century. Understanding how resilient carbon pools and fluxes in these biomes are to climate extremes constitutes a large uncertainty in our ability to understand regional carbon balance. We use a 7 year record (2007-2013) of continuous measurements of net ecosystem exchange of carbon (NEE) and its components (gross primary productivity (GPP) and ecosystem respiration (Re) made over the New Mexico Elevation Gradient (NMEG) network of flux tower sites (desert grassland, creosote shrubland, juniper savanna, piñon-juniper woodland, ponderosa pine and subalpine mixed conifer) to test hypotheses about the biome-specific sensitivity of carbon cycling to both drought and temperature extremes. In particular, we focus on the functional responses in these biomes to the extended drought in this region from 2011-2013, which has triggered extensive mortality in many biomes. We used time series of climatic variables, radiation absorbed by vegetation, sap flux, soil moisture storage, and remotely sensed structural and functional data, including rates of mortality, to compare the biome-specific mechanisms behind these responses. We also produce biome-specific functional response surfaces of productivity and respiration to VPD, temperature and soil water availability. Decreases in annual NEP from the relatively wet year of 2010 to the severe drought year 2011 ranged from 60-165 g C m-2 y-1 across the gradient, due more to decreases in GPP than Re. We observed the greatest sensitivity to both temperature and precipitation extremes in

  1. The investigation of active Martian dune fields using very high resolution photogrammetric measurements

    NASA Astrophysics Data System (ADS)

    Kim, Jungrack; Kim, Younghwi; Park, Minseong

    2016-10-01

    . Acknowledgements:The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under iMars grant agreement Nr. 607379.

  2. Leading Wave Amplitude of a Tsunami

    NASA Astrophysics Data System (ADS)