The Humanities: Interconnections.

ERIC Educational Resources Information Center

Salomone, Ronald E., Ed.

1985-01-01

Focusing on a wide range of interdisciplinary themes and ideas for humanities instruction, the 17 articles in this journal issue discuss the following topics: (1) literature, humanities, and the adult learner; (2) the role of the humanities in educating for a democracy; (3) humanities in the marketplace; (4) literature versus "great books" in high…

Human rights from the grassroots up: Vermont's campaign for universal health care.

PubMed

McGill, Mariah

2012-06-15

In 2008, the Vermont Workers' Center launched the "Healthcare Is a Human Right Campaign," a grassroots campaign to secure the creation of a universal health care system in Vermont. Campaign organizers used a human rights framework to mobilize thousands of voters in support of universal health care. In response to this extraordinary grassroots effort, the state legislature passed health care legislation that incorporates human rights principles into Vermont law and provides a framework for universal health care. The United States has often lagged behind other nations in recognizing economic, social, and cultural (ESC) rights, including the right to health. Nonetheless, activists have begun to incorporate ESC rights into domestic advocacy campaigns, and state and local governments are beginning to respond where the federal government has not. Vermont serves as a powerful example of how a human rights framework can inform health care policy and inspire grassroots campaigns in the United States. This three-part article documents the Vermont Workers' Center campaign and discusses the impact that human rights activity at the grassroots level may have on attitudes towards ESC rights in the United States. The first part describes the Vermont health care crisis and explains why the center adopted international human rights principles for their campaign. The article then goes on to discuss the three-year campaign and analyze the health care reform bill that the Vermont legislature passed. Finally, the article discusses the campaign's local and national impact. Copyright © 2012 McGill.

Selling: A Non-traditional Human Service Skill.

ERIC Educational Resources Information Center

McClam, Tricia; Woodside, Marianne

1999-01-01

Interviews with human service professional across the United States identify selling as a helpful and often necessary skill for effective service delivery. Article introduces selling as a human service skill, explores its benefits to service delivery, and discusses its implications for human service education. (Author/GCP)

Our Fat Future: Translating Adipose Stem Cell Therapy.

PubMed

Nordberg, Rachel C; Loboa, Elizabeth G

2015-09-01

Human adipose stem cells (hASCs) have the potential to treat patients with a variety of clinical conditions. Recent advancements in translational research, regulatory policy, and industry have positioned hASCs on the threshold of clinical translation. We discuss the progress and challenges of bringing adipose stem cell therapy into mainstream clinical use. This article details the advances made in recent years that have helped move human adipose stem cell therapy toward mainstream clinical use from a translational research, regulatory policy, and industrial standpoint. Four recurrent themes in translational technology as they pertain to human adipose stem cells are discussed: automated closed-system operations, biosensors and real-time monitoring, biomimetics, and rapid manufacturing. In light of recent FDA guidance documents, regulatory concerns about adipose stem cell therapy are discussed. Finally, an update is provided on the current state of clinical trials and the emerging industry that uses human adipose stem cells. This article is expected to stimulate future studies in translational adipose stem cell research. ©AlphaMed Press.

The tough decisions that no one wants to make.

PubMed

Taylor, Joe; Jacobs, Michael

2003-01-01

This article examines prescription drug benefit plan trends: past, current, short-term future and long-term future. It includes a brief discussion of each cost trend and its drivers, then asks the question, "What can be done to protect the pharmacy benefit budget, yet provide what is needed?" from three perspectives: (1) business, (2) stakeholders (management, human resource groups, physicians, employees) and (3) patients (employees and dependents). The article discusses therapeutic guidelines, physician education, reimbursement issues, distribution channels and the impact of business decisions on employees, dependents, stockholders, shareholder value, management, human resources and decision makers' own careers.

Human cloning and 'posthuman' society.

PubMed

Blackford, Russell

2005-01-01

Since early 1997, when the creation of Dolly the sheep by somatic cell nuclear transfer was announced in Nature, numerous government reports, essays, articles and books have considered the ethical problems and policy issues surrounding human reproductive cloning. In this article, I consider what response a modern liberal society should give to the prospect of human cloning, if it became safe and practical. Some opponents of human cloning have argued that permitting it would place us on a slippery slope to a repugnant future society, comparable to that portrayed in Aldous Huxley's novel, Brave New World. I conclude that, leaving aside concerns about safety, none of the psychological or social considerations discussed in this article provides an adequate policy justification for invoking the state's coercive powers to prevent human cloning.

Pathology of the human pituitary adenomas

PubMed Central

Kajiya, Hanako; Takei, Mao; Egashira, Noboru; Tobita, Maya; Takekoshi, Susumu; Teramoto, Akira

2008-01-01

This article describes pertinent aspects of histochemical and molecular changes of the human pituitary adenomas. The article outlines individual tumor groups with general, specific and molecular findings. The discussion further extends to the unusual adenomas or carcinomas. The description in this article are pertinent not only for the practicing pathologists who are in the position of making proper diagnosis, but also for the pituitary research scientists who engage in solving basic problems in pituitary neoplasms by histochemistry and molecular biology. PMID:18688636

Community College Humanities Review, 1985-86, Number 7.

ERIC Educational Resources Information Center

Megginson, W. J., Ed.

1986-01-01

Designed as a forum for discussion of substantive issues in humanities disciplines and the place of the humanities in higher education, this journal offers articles, book reviews, and reports covering a variety of humanities-related topics. This issue contains: (1) "The Feasibility of Educational Change," by Richard Ekman; (2) "The Humanities and…

Urban transitions: on urban resilience and human-dominated ecosystems.

PubMed

Ernstson, Henrik; van der Leeuw, Sander E; Redman, Charles L; Meffert, Douglas J; Davis, George; Alfsen, Christine; Elmqvist, Thomas

2010-12-01

Urbanization is a global multidimensional process paired with increasing uncertainty due to climate change, migration of people, and changes in the capacity to sustain ecosystem services. This article lays a foundation for discussing transitions in urban governance, which enable cities to navigate change, build capacity to withstand shocks, and use experimentation and innovation in face of uncertainty. Using the three concrete case cities--New Orleans, Cape Town, and Phoenix--the article analyzes thresholds and cross-scale interactions, and expands the scale at which urban resilience has been discussed by integrating the idea from geography that cities form part of "system of cities" (i.e., they cannot be seen as single entities). Based on this, the article argues that urban governance need to harness social networks of urban innovation to sustain ecosystem services, while nurturing discourses that situate the city as part of regional ecosystems. The article broadens the discussion on urban resilience while challenging resilience theory when addressing human-dominated ecosystems. Practical examples of harnessing urban innovation are presented, paired with an agenda for research and policy.

Ethics and Scientific Publication

ERIC Educational Resources Information Center

Benos, Dale J.; Fabres, Jorge; Farmer, John; Gutierrez, Jessica P.; Hennessy, Kristin; Kosek, David; Lee, Joo Hyoung; Olteanu, Dragos; Russell, Tara; Wang, Kai

2005-01-01

This article summarizes the major categories of ethical violations encountered during submission, review, and publication of scientific articles. We discuss data fabrication and falsification, plagiarism, redundant and duplicate publication, conflict of interest, authorship, animal and human welfare, and reviewer responsibility. In each section,…

Humanism and science: a reaction.

PubMed

Wampold, Bruce E

2012-12-01

Authors in this section have noted that humanism is intrinsic to psychotherapy, although disagreements remain. One of the disagreements is about the role of science in humanism. In this reaction, I contend that humanism, as discussed in these articles, is a legitimate theory to be subjected to scientific scrutiny. (c) 2012 APA, all rights reserved.

Whither motoneurons?

PubMed

Brownstone, Robert M; Stuart, Douglas G

2011-08-29

In the preceding series of articles, the history of vertebrate motoneuron and motor unit neurobiological studies has been discussed. In this article, we select a few examples of recent advances in neuroscience and discuss their application or potential application to the study of motoneurons and the control of movement. We conclude, like Sherrington, that in order to understand normal, traumatized, and diseased human behavior, it is critical to continue to study motoneuron biology using all available and emerging tools. This article is part of a Special Issue entitled Historical Review. 2011 Elsevier B.V. All rights reserved.

Red in Tooth, Claw, and Trigger Finger

ERIC Educational Resources Information Center

Barash, David P.

2005-01-01

Quoting literary and scientific works, the duality of good and evil in human nature is analyzed. Article discusses mankind's detrimental behavior towards the environment and extreme acts of violence among human beings while examining similar violent behavior in animals. It is concluded that humanity's deeds stem from shared cultural traits,…

The limits of narrative: provocations for the medical humanities.

PubMed

Woods, Angela

2011-12-01

This paper aims to (re)ignite debate about the role of narrative in the medical humanities. It begins with a critical review of the ways in which narrative has been mobilised by humanities and social science scholars to understand the experience of health and illness. I highlight seven dangers or blind spots in the dominant medical humanities approach to narrative, including the frequently unexamined assumption that all human beings are 'naturally narrative'. I then explore this assumption further through an analysis of philosopher Galen Strawson's influential article 'Against Narrativity'. Strawson rejects the descriptive claim that "human beings typically see or live or experience their lives as a narrative" and the normative claim that "a richly Narrative outlook is essential to a well-lived life, to true or full personhood". His work has been taken up across a range of disciplines, but its implications in the context of health and illness have not yet been sufficiently discussed. This article argues that 'Against Narrativity' can and should stimulate robust debate within the medical humanities regarding the limits of narrative, and concludes by discussing a range of possibilities for venturing 'beyond narrative'.

Designer human tissue: coming to a lab near you.

PubMed

Hay, David C; O'Farrelly, Cliona

2018-07-05

Human pluripotent stem cells (PSCs) offer a scalable alternative to primary and transformed human tissue. PSCs include human embryonic stem cells, derived from the inner cell mass of blastocysts unsuitable for human implantation; and induced PSCs, generated by the reprogramming of somatic cells. Both cell types display the ability to self-renew and retain pluripotency, promising an unlimited supply of human somatic cells for biomedical application. A distinct advantage of using PSCs is the ability to select for genetic background, promising personalized modelling of human biology 'in a dish' or immune-matched cell-based therapies for the clinic. This special issue will guide the reader through stem cell self-renewal, pluripotency and differentiation. The first articles focus on improving cell fidelity, understanding the innate immune system and the importance of materials chemistry, biofabrication and bioengineering. These are followed by articles that focus on industrial application, commercialization and label-free assessment of tissue formation. The special issue concludes with an article discussing human liver cell-based therapies past, present and future.This article is part of the theme issue 'Designer human tissue: coming to a lab near you'. © 2018 The Authors.

A Feminist Posthumanist Ecopedagogy in/for/with AnimalScapes

ERIC Educational Resources Information Center

Lloro-Bidart, Teresa

2018-01-01

Extending and challenging Arun Appadurai's anthropocentric "scapes," this article converses with feminist posthumanism, ecofeminism, and the political ecology of education to develop a more-than-human ecopedagogy in/for/with animalScapes. After outlining the article's theoretical framework, I briefly discuss the research cases informing…

Portrayal of the Human Resource Crisis and Accountability in Healthcare: A Qualitative Analysis of Ugandan Newspapers

PubMed Central

Wojczewski, Silvia; Willcox, Merlin; Mubangizi, Vincent; Hoffmann, Kathryn; Peersman, Wim; Niederkrotenthaler, Thomas; Natukunda, Silvia; Maling, Samuel; Maier, Manfred; Mant, David; Kutalek, Ruth

2015-01-01

Background Uganda is one of the 57 countries with a critical shortage of health workers. The aim of this study was to determine how the human resources and health service crisis was covered in Ugandan newspapers and, in particular, how the newspapers attributed accountability for problems in the health services. Methods We collected all articles related to health workers and health services for the calendar year 2012 in the two largest national newspapers in Uganda (collection on daily basis) and in one local newspaper (collection on weekly basis). These articles were analysed qualitatively regarding the main themes covered and attribution of accountability. Results The two more urban national newspapers published 229 articles on human resources and health services in Uganda (on average over two articles per week), whereas the local more rural newspaper published only a single article on this issue in the 12 month period. The majority of articles described problems in the health service without discussing accountability. The question of accountability is raised in only 46% of articles (106 articles). The responsibility of the government was discussed in 50 articles (21%), and negligence, corruption and misbehaviour by individual health workers was reported in 56 articles (25%). In the articles about corruption (n=35), 60% (21 articles) mention corruption by health workers and 40% (14 articles) mention corruption by government officials. Six articles defended the situation of health workers in Uganda. Conclusions The coverage of accountability in the Ugandan newspapers surveyed is insufficient to generate informed debate on what political actions need to be taken to improve the crisis in health care and services. There exists not only an “inverse care law” but also an “inverse information law”: those sections of society with the greatest health needs and problems in accessing quality health care receive the least information about health services. PMID:25837490

Portrayal of the human resource crisis and accountability in healthcare: a qualitative analysis of ugandan newspapers.

PubMed

Wojczewski, Silvia; Willcox, Merlin; Mubangizi, Vincent; Hoffmann, Kathryn; Peersman, Wim; Niederkrotenthaler, Thomas; Natukunda, Silvia; Maling, Samuel; Maier, Manfred; Mant, David; Kutalek, Ruth

2015-01-01

Uganda is one of the 57 countries with a critical shortage of health workers. The aim of this study was to determine how the human resources and health service crisis was covered in Ugandan newspapers and, in particular, how the newspapers attributed accountability for problems in the health services. We collected all articles related to health workers and health services for the calendar year 2012 in the two largest national newspapers in Uganda (collection on daily basis) and in one local newspaper (collection on weekly basis). These articles were analysed qualitatively regarding the main themes covered and attribution of accountability. The two more urban national newspapers published 229 articles on human resources and health services in Uganda (on average over two articles per week), whereas the local more rural newspaper published only a single article on this issue in the 12 month period. The majority of articles described problems in the health service without discussing accountability. The question of accountability is raised in only 46% of articles (106 articles). The responsibility of the government was discussed in 50 articles (21%), and negligence, corruption and misbehaviour by individual health workers was reported in 56 articles (25%). In the articles about corruption (n=35), 60% (21 articles) mention corruption by health workers and 40% (14 articles) mention corruption by government officials. Six articles defended the situation of health workers in Uganda. The coverage of accountability in the Ugandan newspapers surveyed is insufficient to generate informed debate on what political actions need to be taken to improve the crisis in health care and services. There exists not only an "inverse care law" but also an "inverse information law": those sections of society with the greatest health needs and problems in accessing quality health care receive the least information about health services.

Human Rights Education: Imaginative Possibilities for Creating Change

ERIC Educational Resources Information Center

Bajaj, Monisha

2015-01-01

Background/Context: Human rights education has proliferated in the past four decades and can be found in policy discussions, textbook reforms, and grassroots initiatives across the globe. This article specifically explores the role of creativity and imagination in human rights education (HRE) by focusing on a case study of one non-governmental…

Consumers, Creators or Commentators? Problems of Audience and Mission in the Digital Humanities

ERIC Educational Resources Information Center

Prescott, Andrew

2012-01-01

A 2008 article by Patrick Juola describes the digital humanities community as marginal to mainstream academic discussions and suggests that its work has little scholarly impact. At the same time, mainstream humanities scholars are using digital resources more and more, but these resources are chiefly produced by libraries and commercial…

Teaching Human Development: A Case for Blended Learning

ERIC Educational Resources Information Center

Cottle, Nathan R.; Glover, Rebecca J.

2011-01-01

This article makes a case for the use of blended learning in teaching human development as a means to encourage higher-order student learning outcomes. The authors review literature regarding the use and effectiveness of blended learning, discuss an illustrative example of a redesign of a human development course, present outcomes from a…

Human Dimensions of Forest Disturbance by Insects: An International Synthesis

Treesearch

Courtney G. Flint; Bonnie McFarlene; Martin Muller

2008-01-01

Ecological disturbances of forests by insects have a complex array of associated human dimensions presenting complications for natural resource decision making and relationships between stakeholders and managers. This article discusses the human context of forest disturbances by insects by reviewing four cases of bark beetle forest disturbance from British Columbia in...

Endocrine system: part 2.

PubMed

Hendry, Charles; Farley, Alistair; McLafferty, Ella; Johnstone, Carolyn

2014-06-03

This article, the last in the life sciences series, is the second of two articles on the endocrine system. It discusses human growth hormone, the pancreas and adrenal glands. The relationships between hormones and their unique functions are also explored. It is important that nurses understand how the endocrine system works and its role in maintaining health to provide effective care to patients. Several disorders caused by human growth hormone or that affect the pancreas and adrenal glands are examined.

A Whole New World of Interventions: The Performance Technologist as Integrating Generalist.

ERIC Educational Resources Information Center

Hutchison, Cathleen Smith; Stein, Faith S.

1997-01-01

The authors update an article on intervention, discussing career development, communications, feedback, financial, human development, information, instructional, labor relations, measurement and evaluation, quality improvement, resource, reward and recognition, and selection systems; documentation and standards; ergonomics and human factors;…

A review of low-level air pollution and adverse effects on human health: implications for epidemiological studies and public policy

PubMed Central

Olmo, Neide Regina Simões; do Nascimento Saldiva, Paulo Hilário; Braga, Alfésio Luís Ferreira; Lin, Chin An; de Paula Santos, Ubiratan; Pereira, Luiz Alberto Amador

2011-01-01

The aim of this study was to review original scientific articles describing the relationship between atmospheric pollution and damage to human health. We also aimed to determine which of these studies mentioned public policy issues. Original articles relating to atmospheric pollution and human health published between 1995 and 2009 were retrieved from the PubMed database and analyzed. This study included only articles dealing with atmospheric pollutants resulting primarily from vehicle emissions. Three researchers were involved in the final selection of the studies, and the chosen articles were approved by at least two of the three researchers. Of the 84 non-Brazilian studies analyzed, 80 showed an association between atmospheric pollution and adverse effects on human health. Moreover, 66 showed evidence of adverse effects on human health, even at levels below the permitted emission standards. Three studies mentioned public policies aimed at changing emission standards. Similarly, the 29 selected Brazilian studies reported adverse associations with human health, and 27 showed evidence of adverse effects even at levels below the legally permitted emission standards. Of these studies, 16 mentioned public policies aimed at changing emission standards. Based on the Brazilian and non-Brazilian scientific studies that have been conducted, it can be concluded that, even under conditions that are compliant with Brazilian air quality standards, the concentration of atmospheric pollutants in Brazil can negatively affect human health. However, as little discussion of this topic has been generated, this finding demonstrates the need to incorporate epidemiological evidence into decisions regarding legal regulations and to discuss the public policy implications in epidemiological studies. PMID:21655765

Computational Thinking: A Digital Age Skill for Everyone

ERIC Educational Resources Information Center

Barr, David; Harrison, John; Conery, Leslie

2011-01-01

In a seminal article published in 2006, Jeanette Wing described computational thinking (CT) as a way of "solving problems, designing systems, and understanding human behavior by drawing on the concepts fundamental to computer science." Wing's article gave rise to an often controversial discussion and debate among computer scientists,…

Psycholinguistics.

ERIC Educational Resources Information Center

Fillenbaum, Samuel

This article provides a discussion of current topics in psycholinguistics and of the current research on these problems. The author discusses current thought on the biological foundations of language and the problem of universals. If human language is a species-particular achievement contingent upon a biological endowment, there should be certain…

Symposium on Contemporary Challenges

ERIC Educational Resources Information Center

Berry, David A.; Graff, Gerald; Nelson, Cary

2010-01-01

In this article, the authors discuss contemporary challenges. David Berry offers advice on teaching the humanities at a community college; Gerald Graff examines how the traditional organization of universities undermines student learning; and Cary Nelson considers the effects on the humanities of the increasing reliance on contingent faculty.

Reconsidering Human Performance Technology

ERIC Educational Resources Information Center

Jang, Hwan Young

2008-01-01

This article discusses three perceived challenges in the field of human performance technology: a missing link from training to performance, limitations in gap analysis and cause analysis, and a lack of attention to business and organization performance. It then provides possible alternatives for each issue, such as instructional system…

Modeling in Big Data Environments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Endert, Alexander; Szymczak, Samantha; Gunning, Dave

Human-Centered Big Data Research (HCBDR) is an area of work that focuses on the methodologies and research areas focused on understanding how humans interact with “big data”. In the context of this paper, we refer to “big data” in a holistic sense, including most (if not all) the dimensions defining the term, such as complexity, variety, velocity, veracity, etc. Simply put, big data requires us as researchers of to question and reconsider existing approaches, with the opportunity to illuminate new kinds of insights that were traditionally out of reach to humans. The purpose of this article is to summarize themore » discussions and ideas about the role of models in HCBDR at a recent workshop. Models, within the context of this paper, include both computational and conceptual mental models. As such, the discussions summarized in this article seek to understand the connection between these two categories of models.« less

[Productivity and academic assessment in the Brazilian public health field: challenges for Human and Social Sciences research].

PubMed

Bosi, Maria Lúcia Magalhães

2012-12-01

This article analyzes some challenges for knowledge output in the human and social sciences in the public health field, under the current academic assessment model in Brazil. The article focuses on the qualitative research approach in human and social sciences, analyzing its status in comparison to the other traditions vying for hegemony in the public health field, conjugating the dialogue with the literature, especially the propositions pertaining to the social fields present in the work of Pierre Bourdieu, with elements concerning the field's dynamics, including some empirical data. Challenges identified in the article include hurdles to interdisciplinary dialogue and equity in the production of knowledge, based on recognition of the founding place of human and social sciences in the public health field. The article discusses strategies to reshape the current correlation of forces among centers of knowledge in public health, especially those capable of impacting the committees and agendas that define the accumulation of symbolic and economic capital in the field.

A Model Human Sexuality--HIV/AIDS Prevention and Intervention Service-Learning Program

ERIC Educational Resources Information Center

Stewart, Clarence, M., Jr.

2005-01-01

This article deals with a service-learning program focused on human sexuality and HIV/AIDS prevention and intervention at the Howard University Department of Health, Human Performance and Leisure Studies. Topics discussed include how this program was created, an overview of peer education, HIV/AIDS peer education training, and services provided to…

Securing the Human: The Journey Toward World Law and Justice. The Whole Earth Papers, No. 14.

ERIC Educational Resources Information Center

Mische, Patricia; And Others

The document contains a variety of papers that examine the linkages between local concerns and global concerns and explore alternative world futures. An introductory article, "Securing the Human," discusses how the world community needs to develop adequate means to deal with crimes against humans. These means include sound analysis, spiritual…

The Limits of Narrative: Provocations for the Medical Humanities

PubMed Central

Woods, Angela

2014-01-01

This paper aims to (re)ignite debate about the role of narrative in the medical humanities. It begins with a critical review of the ways in which narrative has been mobilised by humanities and social science scholars to understand the experience of health and illness. I highlight seven dangers or blind spots in the dominant medical humanities approach to narrative, including the frequently unexamined assumption that all human beings are “naturally narrative.” I then explore this assumption further through an analysis of philosopher Galen Strawson’s influential article “Against Narrativity.” Strawson rejects the descriptive claim that “human beings typically see or live or experience their lives as a narrative” and the normative claim that “a richly Narrative outlook is essential to a well-lived life, to true or full personhood.” His work has been taken up across a range of disciplines but its implications in the context of health and illness have not yet been sufficiently discussed. This article argues that “Against Narrativity” can and should stimulate robust debate within the medical humanities regarding the limits of narrative, and concludes by discussing a range of possibilities for venturing “beyond narrative.” PMID:22038696

[Ethics and laws related to human subject research].

PubMed

Chiu, Hui-Ju; Lee, Ya-Ling; Chang, Su-Fen

2011-10-01

Advances in medical technology rely on human subject research to test the effects on real patients of unproven new drugs, equipment and techniques. Illegal human subject research happens occasionally and has led to subject injury and medical disputes. Familiarity with the laws and established ethics related to human subject research can minimize both injury and disputes. History is a mirror that permits reflection today on past experience. Discussing the Nuremberg Code, the Declaration of Helsinki and Belmont Report, this article describes the laws, ethics, history and news related to human subject research as well as the current definition and characteristics of human subject research. Increasing numbers of nurses serve as research nurses and participate in human subject research. The authors hope this article can increase research nurse knowledge regarding laws and ethics in order to protect human research subjects adequately.

Children in Contemporary Society: Child Ecology.

ERIC Educational Resources Information Center

Frank, Mary, Ed.

This collection of short articles focuses on various dimensions of childhood ecology. Section I introduces a conceptual framework for the study of childhood ecology and poses 4 methodological principles for human development specialists. Four ecological subsystems are identified and discussed briefly. Section II discusses the family microsystem in…

People in the Community.

ERIC Educational Resources Information Center

Vredeveld, George M.; And Others

1983-01-01

The theme article of this issue provides a conceptual introduction for teachers to the local community as a market. The introduction discusses the scarcity role in forcing decisions, individuals as producers, specialization of human resources, payment of human resources, and how wages reflect market conditions. Four grade-level specific units…

Human immunodeficiency virus.

PubMed

Skinner, Anita

2016-11-23

What was the nature of the CPD activity, practice-related feedback and/or event and/or experience in your practice? The CPD article discussed the importance of human immunodeficiency virus (HIV) testing and diagnosing the condition as early as possible, so that antiretroviral treatment can be initiated and patient outcomes improved.

Bioteaching Ethics and the Researcher-Teacher: Considerations for Teacher Education.

ERIC Educational Resources Information Center

Lovat, Terence J.

1995-01-01

This article examines the teacher researcher movement, discussing ethical matters related to action research. In the medical domain, biomedical ethics directs human interventions resulting from clinical and research practice. The paper suggests a discipline called "bioteaching ethics" could help direct human interventionary actions of teachers…

Human smuggling in Austria: a comparative analysis of data on smuggled migrants from former Yugoslavia and the Russian Federation.

PubMed

Peterka-Benton, Daniela

2011-01-01

This article provides a summary of the author’s research on human smuggling in Austria comparing migrants from Former Yugoslavia and the Russian Federation. The project’s primary intent was to collect more detailed information on migrants seeking asylum in Austria and their use of smuggling services to leave their home countries, including detailed information on demographics, force or threat of force by smugglers, routes and methods of transportation, costs of smuggling, payment methods, and deeper perceptual questions regarding the flight. Another central premise of the article discusses how current distinctions between human smuggling and human trafficking are arbitrary in many regards.

Student/Worker/Carer: The Intersecting Priorities of Arts Students

ERIC Educational Resources Information Center

Maher, JaneMaree; Mitchell, Jennifer; Brown, Kate

2009-01-01

This article reports on a focus group study of student experience and learning in a large humanities and social science faculty in Australia. The study explored student study/work/life issues, and student learning experiences. The article reports specifically on a discussion about combining meaningful learning in university classrooms with other…

Issues in protection of human subjects in internet research.

PubMed

Im, Eun-Ok; Chee, Wonshik

2002-01-01

Despite the increasing use of the Internet among nurses, the use of the Internet in nursing research has been rarely discussed and critiqued in terms of issues in protection of human subjects. In this article, issues in protection of human subjects in Internet research are explored by analyzing an Internet study to propose directions for human protection in Internet research. Issues raised through the study include those related to (a) anonymity and confidentiality, (b) security, (c) self-determination and authenticity, (d) full disclosure, and (e) fair treatment. Based on discussion of the five issues, development of standardized guidelines, investigator triangulation, and information sharing are proposed as directions for protection of human subjects in Internet research.

Classical Humanities for High School Students.

ERIC Educational Resources Information Center

Champlin, Marjorie W.

Several creative classroom activities related to literary studies are discussed in this article. The plays of Plautus, Aeschylus, Sophocles, Euripides, Shakespeare, Giraudoux, O'Neill, Anouilh, T. S. Eliot, and Goethe are read as the basis for comparative studies. The author discusses the problem of reading Latin plays in translation and comments…

The Human Rights Approach to Education in International Organisations

ERIC Educational Resources Information Center

Hufner, Klaus

2011-01-01

In this article, the work of three international governmental organisations (IGOs) dealing with human rights will be discussed, namely the United Nations Educational, Scientific and Cultural Organization (UNESCO), the United Nations Children's Fund (UNICEF) and the Council of Europe (CoE). In the first section, the main characteristics of the…

Perspectives on Human-Computer Interface: Introduction and Overview.

ERIC Educational Resources Information Center

Harman, Donna; Lunin, Lois F.

1992-01-01

Discusses human-computer interfaces in information seeking that focus on end users, and provides an overview of articles in this section that (1) provide librarians and information specialists with guidelines for selecting information-seeking systems; (2) provide producers of information systems with directions for production or research; and (3)…

"No DH, No Interview"

ERIC Educational Resources Information Center

Pannapacker, William

2012-01-01

In this article, the author discusses digital humanities (DH) and what future it holds for graduate students who are riding the digital-humanities bandwagon. He spoke with several graduate students about their interest in the field: how they got into it and began their first projects. Laura Mandell, director of the Initiative for Digital…

College Humanities Majors in Post-Soviet Russia

ERIC Educational Resources Information Center

Sokolov, A. V.

2005-01-01

This article discusses the distinguishing traits and features of college humanities majors in post-Soviet Russia. It, presents the social-pedagogical surveys that the author conducted in various institutions of higher learning in St. Petersburg, using a variety of sociological methods: from mass and group surveys to interviews, the keeping of…

The Needs of Humans: A Beginning

ERIC Educational Resources Information Center

Scott, Marie

2006-01-01

This article focuses on a teaching method developed by Maria Montessori, starting with activities in the primary classroom, which are continued through the elementary years. The author discusses a few child-centered techniques in preparing children for their work within a larger community--the whole human family. In the Montessori environment, the…

Proceedings of the Community College Humanities Association, Number 6, 1984-1985.

ERIC Educational Resources Information Center

Rassweiler, Anne D., Ed.; Hylander, Joan W., Ed.

A series of reports reflecting the activities of the Community College Humanities Association (CCHA) are presented in these proceedings. The first article, "Teaching Professional Ethics: Proceed, But with Caution," by Richard A. Wright, argues that extreme care must be taken in developing and teaching professional ethics, discussing what…

Effectiveness of the Sexual Attitude Restructuring Curriculum amongst Taiwanese Graduate Students

ERIC Educational Resources Information Center

Lin, Yi-Li; Lin, Yen-Chin

2018-01-01

This article discusses the effectiveness of the Sexual Attitude Restructuring (SAR) curriculum in developing positive sexual attitudes amongst Taiwanese graduate students in human sexuality. Through purposive sampling, 32 graduate students in human sexuality were selected to participate in the study. Before and after providing participants with a…

Reflections and Future Prospects for Evaluation in Human Resource Development

ERIC Educational Resources Information Center

Han, Heeyoung; Boulay, David

2013-01-01

Human resource development (HRD) evaluation has often been criticized for its limited function in organizational decision making. This article reviews evaluation studies to uncover the current status of HRD evaluation literature. The authors further discuss general evaluation theories in terms of value, use, and evaluator role to extend the…

Teaching to Transform, Transforming to Teach: Exploring the Role of Teachers in Human Rights Education in India

ERIC Educational Resources Information Center

Bajaj, Monisha

2011-01-01

Background: Human rights education initiatives have proliferated in the past three decades and can be found in policy discussions, textbook reforms and grassroots initiatives across the globe. This article specifically explores the role of teachers in human rights education (HRE) by focusing on a case study of one non-governmental organisation's…

Use Of Transgenic Mice In UDP-Glucuronosyltransferase (UGT) Studies

PubMed Central

Ou, Zhimin; Huang, Min; Zhao, Lizi; Xie, Wen

2009-01-01

Transgenic mouse models are useful to understand the function and regulation of drug metabolizing enzymes in vivo. This article is intended to describe the general strategies and to discuss specific examples on how to use transgenic, gene knockout, and humanized mice to study the function as well as genetic and pharmacological regulation of UDP-glucuronosyltransferases (UGTs). The physiological and pharmacological implications of transcription factor-mediated UGT regulation will also be discussed. The UGT-regulating transcription factors to be discussed in this article include nuclear hormone receptors (NRs), aryl hydrocarbon receptor (AhR), and nuclear factor erythroid 2-related factor 2 (Nrf2). PMID:20070245

Contextual Sensing: Integrating Contextual Information with Human and Technical Geo-Sensor Information for Smart Cities

PubMed Central

Sagl, Günther; Resch, Bernd; Blaschke, Thomas

2015-01-01

In this article we critically discuss the challenge of integrating contextual information, in particular spatiotemporal contextual information, with human and technical sensor information, which we approach from a geospatial perspective. We start by highlighting the significance of context in general and spatiotemporal context in particular and introduce a smart city model of interactions between humans, the environment, and technology, with context at the common interface. We then focus on both the intentional and the unintentional sensing capabilities of today’s technologies and discuss current technological trends that we consider have the ability to enrich human and technical geo-sensor information with contextual detail. The different types of sensors used to collect contextual information are analyzed and sorted into three groups on the basis of names considering frequently used related terms, and characteristic contextual parameters. These three groups, namely technical in situ sensors, technical remote sensors, and human sensors are analyzed and linked to three dimensions involved in sensing (data generation, geographic phenomena, and type of sensing). In contrast to other scientific publications, we found a large number of technologies and applications using in situ and mobile technical sensors within the context of smart cities, and surprisingly limited use of remote sensing approaches. In this article we further provide a critical discussion of possible impacts and influences of both technical and human sensing approaches on society, pointing out that a larger number of sensors, increased fusion of information, and the use of standardized data formats and interfaces will not necessarily result in any improvement in the quality of life of the citizens of a smart city. This article seeks to improve our understanding of technical and human geo-sensing capabilities, and to demonstrate that the use of such sensors can facilitate the integration of different types of contextual information, thus providing an additional, namely the geo-spatial perspective on the future development of smart cities. PMID:26184221

Contextual Sensing: Integrating Contextual Information with Human and Technical Geo-Sensor Information for Smart Cities.

PubMed

Sagl, Günther; Resch, Bernd; Blaschke, Thomas

2015-07-14

In this article we critically discuss the challenge of integrating contextual information, in particular spatiotemporal contextual information, with human and technical sensor information, which we approach from a geospatial perspective. We start by highlighting the significance of context in general and spatiotemporal context in particular and introduce a smart city model of interactions between humans, the environment, and technology, with context at the common interface. We then focus on both the intentional and the unintentional sensing capabilities of today's technologies and discuss current technological trends that we consider have the ability to enrich human and technical geo-sensor information with contextual detail. The different types of sensors used to collect contextual information are analyzed and sorted into three groups on the basis of names considering frequently used related terms, and characteristic contextual parameters. These three groups, namely technical in situ sensors, technical remote sensors, and human sensors are analyzed and linked to three dimensions involved in sensing (data generation, geographic phenomena, and type of sensing). In contrast to other scientific publications, we found a large number of technologies and applications using in situ and mobile technical sensors within the context of smart cities, and surprisingly limited use of remote sensing approaches. In this article we further provide a critical discussion of possible impacts and influences of both technical and human sensing approaches on society, pointing out that a larger number of sensors, increased fusion of information, and the use of standardized data formats and interfaces will not necessarily result in any improvement in the quality of life of the citizens of a smart city. This article seeks to improve our understanding of technical and human geo-sensing capabilities, and to demonstrate that the use of such sensors can facilitate the integration of different types of contextual information, thus providing an additional, namely the geo-spatial perspective on the future development of smart cities.

Using human rights-based approaches to conceptualise lesbian and bisexual women's health inequalities.

PubMed

Fish, Julie; Bewley, Susan

2010-07-01

This article makes a contribution to current debates in human rights-based approaches to lesbian and bisexual (LB) women's health. With reference to concepts embodied in the Yogyakarta Principles, it is proposed that the right to health includes access to health information, participation, equity, equality and non-discrimination. Specifically, the article examines how LB women's health can be considered as a health inequality and discusses international developments to reduce disparities. Drawing on qualitative data collected in an online survey, the article reports on sexual minority women's experiences of health-care. Participants were recruited via a purposive sampling strategy; questionnaires were completed by 6490 respondents of whom 5909 met the study criteria of residence in the UK, sexual orientation and completing the survey once. Analysis revealed four broad themes: heteronormativity in health-care; improving attitudes among healthcare professionals; equality in access; raising awareness and informed communities. The accounts highlight the centrality of human rights principles: fairness, respect, equality, dignity and autonomy. The implications for healthcare policy and practice are discussed including ways to empower staff and service users with knowledge and skills and ensuring non-discrimination in health service delivery.

Extra! Extra! Read All about It! How to Construct a Newsletter: A Student Project

ERIC Educational Resources Information Center

Renard, Monika; Tracy, Kay

2011-01-01

This article discusses a student project that highlights the value of printed employee newsletters as an internal communication tool for organizations. The project provides specific information and directions on how to develop an employee newsletter on human resource topics. Microsoft Word 2007 is used for newsletter formatting. The article also…

A Question of Literacy: Understanding and Renewing the Humanities in a Global World

ERIC Educational Resources Information Center

Gallucci, John A.

2012-01-01

The article discusses the nature of humanistic knowledge. Analyzing the relation between aesthetic judgment, literacy and knowledge as defined by the French seventeenth-century Jansenist school of Port-Royal, the article argues that Port-Royal's interpretation of the enthymeme can be used to define the cognitive basis of aesthetic judgments in the…

It's Not Your Grandmother's Genetics Anymore! (Part 2)

ERIC Educational Resources Information Center

Smith, Mike U.

2014-01-01

In a companion article, I discussed recent developments in genetics and the inadequacies of eight common claims made by biology teachers, followed by suggested replacement language for those statements. In the present article, I address nine more claims, about such topics as whether or not most human characteristics are inherited as simple…

Selenium: Poison and Preventive.

ERIC Educational Resources Information Center

Marmion Howe, Sister

1978-01-01

Selenium is an essential nutrient to the human body, but it can reach toxic levels causing a disease called selenosis. This article discusses selenium, its geographical distribution, toxicity, nutritional role, and carcinogenicity. (MA)

Introduction: Science, Sexuality, and Psychotherapy: Shifting Paradigms.

PubMed

Cerbone, Armand R

2017-08-01

This introduction presents an overview of the current issue (73, 8) of Journal of Clinical Psychology: In Session. This issue features a series of articles, with clinical cases, each presented to illustrate the challenges faced by individuals and couples whose sexual and gender identities and expressions do not comport with traditional and cultural norms. These articles also document the challenges to the therapists who treat them. Considered individually, each article underscores the need to recognize the importance of evidence in guiding psychotherapy in cases involving sexuality. The discussions in each article offer recommendations meant to help and guide psychotherapists. Considered collectively, they raise important questions and considerations about shifting paradigms of human sexuality. Implications for assessment and treatment of cases involving sexuality and gender identity are discussed and recommended. © 2017 Wiley Periodicals, Inc.

Human rights and bioethics.

PubMed

Barilan, Y M; Brusa, M

2008-05-01

In the first part of this article we survey the concept of human rights from a philosophical perspective and especially in relation to the "right to healthcare". It is argued that regardless of meta-ethical debates on the nature of rights, the ethos and language of moral deliberation associated with human rights is indispensable to any ethics that places the victim and the sufferer in its centre. In the second part we discuss the rise of the "right to privacy", particularly in the USA, as an attempt to make the element of personal free will dominate over the element of basic human interest within the structure of rights and when different rights seem to conflict. We conclude by discussing the relationship of human rights with moral values beyond the realm of rights, mainly human dignity, free will, human rationality and response to basic human needs.

APA efforts in promoting human rights and social justice.

PubMed

Leong, Frederick T L; Pickren, Wade E; Vasquez, Melba J T

2017-11-01

This article reviews the American Psychological Association's (APA) efforts in promoting human rights and social justice. Beginning with a historical review of the conceptualizations of human rights and social justice, the social challenges that have faced the United States over time are discussed in relation to the APA's evolving mission and strategic initiatives enacted through its boards, committees, and directorates. From early efforts on the Board for Social and Ethical Responsibility in Psychology and the Board of Ethnic Minority Affairs to the establishment of the Public Interest Directorate, the APA's efforts to address these human rights and social justice challenges through its task force reports, guidelines, and policies are described. Specifically, issues related to diversity and underrepresentation of minority group members and perspective within the APA, as well as women's issues (prochoice, violence against women, sexualization of young girls, human trafficking) were central to these efforts. These minority groups included racial and ethnic minority groups; immigrants and refugees; lesbian, gay, bisexual, transgendered, and queer individuals; and those with disabilities. Later attention shifted to broader social justice challenges within a public health perspective, such as AIDS, obesity, and violence. Also included is a brief discussion of the Hoffman Report. The article ends with a discussion of future directions for the APA's efforts related to human rights and social justice related to health disparities, violent extremism, social inequality, migration, cultural and racial diversity, and an evidence-based approach to programming. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Thought and Creation in Contemporary Education: Theoretical Approaches and Practical Suggestions

ERIC Educational Resources Information Center

Cupertino, Christina; Arantes, Denise R. B.; Melcher, Mariangela F.

2016-01-01

This article discusses the role of creation and thought in contemporary life, education and, in particular, gifted education. Beginning with traditional approaches to creativity, some implications of diverse ways of understanding these two human activities in education are discussed, and reflections upon ways in which the particular concepts of…

Singing' the Black and Blues

ERIC Educational Resources Information Center

Fisher, Diane

2004-01-01

It is so obvious that the sky is blue in the daytime and black at night, but it took the smartest humans thousands of years of observation, thought, discussion, conjecture, and analysis to finally come up with answers that make scientific sense as to why the sky is these colors. This article discusses light and the scientific research…

Controversy in the allometric application of fixed- versus varying-exponent models: a statistical and mathematical perspective.

PubMed

Tang, Huadong; Hussain, Azher; Leal, Mauricio; Fluhler, Eric; Mayersohn, Michael

2011-02-01

This commentary is a reply to a recent article by Mahmood commenting on the authors' article on the use of fixed-exponent allometry in predicting human clearance. The commentary discusses eight issues that are related to criticisms made in Mahmood's article and examines the controversies (fixed-exponent vs. varying-exponent allometry) from the perspective of statistics and mathematics. The key conclusion is that any allometric method, which is to establish a power function based on a limited number of animal species and to extrapolate the resulting power function to human values (varying-exponent allometry), is infused with fundamental statistical errors. Copyright © 2010 Wiley-Liss, Inc.

Education for Personal Life: John MacMurray on Why Learning to Be Human Requires Emotional Discipline

ERIC Educational Resources Information Center

MacAllister, James

2014-01-01

In this article I discuss the philosophy of John MacMurray, and in particular, his little-examined writings on discipline and emotion education. It is argued that discipline is a vital element in the emotion education MacMurray thought central to learning to be human, because for him it takes concerted effort to overcome the human tendency toward…

Metabolic syndrome: is equine disease comparable to what we know in humans?

PubMed Central

Ertelt, Antonia; Barton, Ann-Kristin; Schmitz, Robert R; Gehlen, Heidrun

2014-01-01

This review summarizes similarities and differences between the metabolic syndromes in humans and equines, concerning the anatomy, symptoms, and pathophysiological mechanisms. In particular, it discusses the structure and distribution of adipose tissue and its specific metabolic pathways. Furthermore, this article provides insights and focuses on issues concerning laminitis in horses and cardiovascular diseases in humans, as well as their overlap. PMID:24894908

Tutorial Facilitation in the Humanities Based on the Tenets of Carl Rogers

ERIC Educational Resources Information Center

Heim, Caroline

2012-01-01

This article introduces a model for group facilitation in the humanities based on Carl Rogers' model for group psychotherapy. Certain aspects of Carl Rogers' reflective learning strategies are reappraised and principles, specific only to psychotherapy, are introduced. Five of Rogers' axioms are applied to the tutorial discussion model: a…

A Human Endeavor: Lessons from Shakespeare and Beyond

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bishop, Matt; Frincke, Deb A.

This article discusses human-oriented educational activities that support the study of computer security. It poses the point that technology is perhaps the least important aspect of security solutions, and that because of this, the fields of psychology, literature, business, and political science have significant value for any serious student of the science of security.

Teaching Methods in Nutrition: Free Radicals, Antioxidants, and Human Disease.

ERIC Educational Resources Information Center

Janowiak, John J.

This article presents a teaching methodology for free radical theory and discusses the role of antioxidants in human health. Free radicals are a normal byproduct of respiration, which allows the body to use oxygen, liberate energy, and dispose of harmful substances. The body's antioxidants and nutritional antioxidants quench most of the free…

Lessons from the Dust Bowl: Human-Environment Education on the Great Plains

ERIC Educational Resources Information Center

Porter, Jess

2012-01-01

This article documents regional demand for human-environment educational resources via assessment of public knowledge of the environmental crisis known as the Dust Bowl. The steadily eroding knowledge-base on the topic is discussed along with the desire for enhanced Dust Bowl educational resources. Regionally focused educational activities…

The Aral Sea: A Lesson in Environmental Degradation.

ERIC Educational Resources Information Center

Boyle, Eric D.

This article approaches the Aral Sea's demise as an extreme example of how human development has the potential to destroy the environment. The discussion focuses on two lessons provided by the Aral Sea story: (1) the interdependence between humanity and nature, and the consequences of disregarding the environment in pursuit of progress; and (2)…

The Human Genome Project and Eugenics: Identifying the Impact on Individuals with Mental Retardation.

ERIC Educational Resources Information Center

Kuna, Jason

2001-01-01

This article explores the impact of the mapping work of the Human Genome Project on individuals with mental retardation and the negative effects of genetic testing. The potential to identify disabilities and the concept of eugenics are discussed, along with ethical issues surrounding potential genetic therapies. (Contains references.) (CR)

The Humanities, Higher Education, and Academic Freedom: Three Necessary Arguments--A Forum

ERIC Educational Resources Information Center

Bérubé, Michael; Ruth, Jennifer

2016-01-01

In this article, the authors discuss the aim of their book, "The Humanities, Higher Education, and Academic Freedom: Three Necessary Arguments" (2015). The authors provide an account of the dire employment conditions that have weakened North American universities as professional institutions of teaching and learning. They believe that…

Training Humanities Doctoral Students in Collaborative and Digital Multimedia

ERIC Educational Resources Information Center

Ensslin, Astrid; Slocombe, Will

2012-01-01

This study reports on the pedagogic rationale, didactic design and implications of an AHRC-funded doctoral training scheme in collaborative and digital multimedia in the humanities. In the second part of this article we discuss three areas of provision that were identified as particularly significant and/or controversial. These include (1) desktop…

Practice-Near and Practice-Distant Methods in Human Services Research

ERIC Educational Resources Information Center

Froggett, Lynn; Briggs, Stephen

2012-01-01

This article discusses practice-near research in human services, a cluster of methodologies that may include thick description, intensive reflexivity, and the study of emotional and relational processes. Such methods aim to get as near as possible to experiences at the relational interface between institutions and the practice field.…

Building Social, Human, and Cultural Capital through Parental Involvement

ERIC Educational Resources Information Center

Bjork, Lars G.; Lewis, Wayne D.; Browne-Ferrigno, Tricia; Donkor, Anthony

2012-01-01

This article examines the relationship between schools and society in the United States and uses human, social, and cultural capital theories to reframe the discussion of the role of schools in nurturing parent engagement. We argue that the ramifications of parent engagement in schools transcend functionalist ideas of complying with state and…

Exploring the Partnership between Line Managers and HRM in Greece

ERIC Educational Resources Information Center

Papalexandris, Nancy; Panayotopoulou, Leda

2005-01-01

Purpose: This article seeks to discuss the role that line managers take up concerning human resource management issues among Greek firms and to propose ways for enhancing the synergistic relationship between human resource (HR) and line managers. Design/methodology/approach: It presents the trends of line management involvement in Greek firms,…

Human Performance on the Traveling Salesman and Related Problems: A Review

ERIC Educational Resources Information Center

MacGregor, James N.; Chu, Yun

2011-01-01

The article provides a review of recent research on human performance on the traveling salesman problem (TSP) and related combinatorial optimization problems. We discuss what combinatorial optimization problems are, why they are important, and why they may be of interest to cognitive scientists. We next describe the main characteristics of human…

La Linguistica y el Estructuralismo (Linguistics and Structuralism)

ERIC Educational Resources Information Center

Lugo, Ramon Medina

1976-01-01

This article discusses the relationship between linguistic theory and structuralist philosophy, and explores the possibility of applying structuralist ideas to other human sciences such as anthropology. (Text is in Spanish.) (CLK)

Our time is now - how companion animal veterinarians can transform biomedical science.

PubMed

Mellanby, R J

2015-12-01

Over the past decade, there has been growing interest in the "One Health" agenda, defined by the One Health Initiative to be "a worldwide strategy for expanding interdisciplinary collaborations and communications in all aspects of health care for humans, animals and the environment." The concept has spawned numerous conferences, under- and post-graduate courses and has been the topic of dozens of articles that have discussed how medical doctors, scientists and veterinarians can work together to improve the health of both animals and humans. Although there is widespread agreement about the potential benefits of medical doctors and veterinarians working more closely together, this is far from routine practice for most companion animal veterinarians. This article reflects on why the topic of "One Health" is attracting such interest at the moment and discusses some of the reasons why the "One Health" agenda offers companion animal veterinarians a chance to be centre stage in the global drive to improve the health of both animals and humans. © 2015 British Small Animal Veterinary Association.

Legal Linguistics as a Mutual Arena for Cooperation: Recent Developments in the Field of Applied Linguistics and Law

ERIC Educational Resources Information Center

Engberg, Jan

2013-01-01

This article reports on some of the recent projects and individual works in the field of Legal Linguistics as examples of cooperation between Applied Linguistics and law. The article starts by discussing relevant prototypical concepts of Legal Linguistics. Legal Linguistics scrutinizes interactions between human beings in the framework of legal…

Ethical aspects of human biobanks: a systematic review

PubMed Central

Budimir, Danijela; Polašek, Ozren; Marušić, Ana; Kolčić, Ivana; Zemunik, Tatijana; Boraska, Vesna; Jerončić, Ana; Boban, Mladen; Campbell, Harry; Rudan, Igor

2011-01-01

Aim To systematically assess the existing literature on ethical aspects of human biobanks. Method We searched the Web of Science and PubMed databases to find studies addressing ethical problems in biobanks with no limits set (study design, study population, time period, or language of publication). All identified articles published until November 2010 were included. We analyzed the type of published articles, journals publishing them, involvement of countries/institutions, year of publication, and citations received, and qualitatively assessed every article in order to identify ethical issues addressed by the majority of published research on human biobanking. Results Hundred and fifty four studies satisfied our review criteria. The studies mainly came from highly developed countries and were all published in the last two decades, with over half of them published in 2009 or 2010. They most commonly discussed the informed consent, privacy and identifiability, return of results to participants, importance of public trust, involvement of children, commercialization, the role of ethics boards, international data exchange, ownership of samples, and benefit sharing. Conclusions The focus on ethical aspects is strongly present through the whole biobanking research field. Although there is a consensus on the old and most typical ethical issues, with further development of the field and increasingly complex structure of human biobanks, these issues will likely continue to arise and accumulate, hence requiring constant re-appraisal and continuing discussion. PMID:21674823

Thermal Indices and Thermophysiological Modeling for Heat Stress.

PubMed

Havenith, George; Fiala, Dusan

2015-12-15

The assessment of the risk of human exposure to heat is a topic as relevant today as a century ago. The introduction and use of heat stress indices and models to predict and quantify heat stress and heat strain has helped to reduce morbidity and mortality in industrial, military, sports, and leisure activities dramatically. Models used range from simple instruments that attempt to mimic the human-environment heat exchange to complex thermophysiological models that simulate both internal and external heat and mass transfer, including related processes through (protective) clothing. This article discusses the most commonly used indices and models and looks at how these are deployed in the different contexts of industrial, military, and biometeorological applications, with focus on use to predict related thermal sensations, acute risk of heat illness, and epidemiological analysis of morbidity and mortality. A critical assessment is made of tendencies to use simple indices such as WBGT in more complex conditions (e.g., while wearing protective clothing), or when employed in conjunction with inappropriate sensors. Regarding the more complex thermophysiological models, the article discusses more recent developments including model individualization approaches and advanced systems that combine simulation models with (body worn) sensors to provide real-time risk assessment. The models discussed in the article range from historical indices to recent developments in using thermophysiological models in (bio) meteorological applications as an indicator of the combined effect of outdoor weather settings on humans. Copyright © 2015 John Wiley & Sons, Inc.

Evolutionary awareness.

PubMed

Gorelik, Gregory; Shackelford, Todd K

2014-08-27

In this article, we advance the concept of "evolutionary awareness," a metacognitive framework that examines human thought and emotion from a naturalistic, evolutionary perspective. We begin by discussing the evolution and current functioning of the moral foundations on which our framework rests. Next, we discuss the possible applications of such an evolutionarily-informed ethical framework to several domains of human behavior, namely: sexual maturation, mate attraction, intrasexual competition, culture, and the separation between various academic disciplines. Finally, we discuss ways in which an evolutionary awareness can inform our cross-generational activities-which we refer to as "intergenerational extended phenotypes"-by helping us to construct a better future for ourselves, for other sentient beings, and for our environment.

Toward a Psychology of Human Agency.

PubMed

Bandura, Albert

2006-06-01

This article presents an agentic theory of human development, adaptation, and change. The evolutionary emergence of advanced symbolizing capacity enabled humans to transcend the dictates of their immediate environment and made them unique in their power to shape their life circumstances and the courses their lives take. In this conception, people are contributors to their life circumstances, not just products of them. Social cognitive theory rejects a duality between human agency and social structure. People create social systems, and these systems, in turn, organize and influence people's lives. This article discusses the core properties of human agency, the different forms it takes, its ontological and epistemological status, its development and role in causal structures, its growing primacy in the coevolution process, and its influential exercise at individual and collective levels across diverse spheres of life and cultural systems. © 2006 Association for Psychological Science.

Communicating in a Noisy World.

DTIC Science & Technology

1983-04-18

human communication any source of message distortion from unwanted sound to distracting emotions b16 the receiver may be thought of analogically as...which discusses human communication in the future. The article runs to ten pages of offensive print. It is printed in eight-point type that is 15...the Practice of Management, 3rd ed., p. 129. 8. John Parry, The Psychology of Human Communication , p. 64. 9. Peter F. Drucker, Technology, Management

Indignity and Old Age.

PubMed

Gordon, John-Stewart

2018-05-01

This article examines the nature of human dignity against the background of old age and introduces the novel idea of treating human dignity as a formal principle related to the more foundational notion of indignity. The discussion starts with the objection that the notion of human dignity can be used to justify contrary positions and is therefore inconclusive. This pitfall can be averted by appealing to the notion of indignity rather than dignity in one's moral reasoning and decision-making. Cases of indignity are more primary and indicate the violation of the very core of a human being. The verifiable property of vulnerability is central to this identification of indignity, as is illustrated by reference to the experiences of elderly people. The article argues for applying the concept of human dignity to reverse the conditions that existed before a particular indignity emerged, rather than trying to define positively the notion of human dignity in the first place. © 2018 John Wiley & Sons Ltd.

Library and Information Resources and Users of Digital Resources in the Humanities

ERIC Educational Resources Information Center

Warwick, Claire; Terras, Melissa; Galina, Isabel; Huntington, Paul; Pappa, Nikoleta

2008-01-01

Purpose: The purpose of this article is to discuss the results of the Log Analysis of Internet Resources in the Arts and Humanities (LAIRAH) study. It aims to concentrate upon the use and importance of information resources, physical research centres and digital finding aids in scholarly research. Design/methodology/approach: Results are presented…

Confronting Analytical Dilemmas for Understanding Complex Human Interactions in Design-Based Research from a Cultural-Historical Activity Theory (CHAT) Framework

ERIC Educational Resources Information Center

Yamagata-Lynch, Lisa C.

2007-01-01

Understanding human activity in real-world situations often involves complicated data collection, analysis, and presentation methods. This article discusses how Cultural-Historical Activity Theory (CHAT) can inform design-based research practices that focus on understanding activity in real-world situations. I provide a sample data set with…

Physical Education as a Prerequisite for the Possibility of Human Virtue

ERIC Educational Resources Information Center

Surprenant, Chris W.

2014-01-01

This article examines the role of physical education in the process of moral education, and argues that physical education is a necessary prerequisite for the possibility of human virtue. This discussion is divided into four parts. First, I examine the nature of morality and moral decision-making. Drawing on the moral theories presented by Plato,…

Cultural, Human, and Social Capital as Determinants of Corporal Punishment: Toward an Integrated Theoretical Model.

ERIC Educational Resources Information Center

Xu, Xiaohe; Tung, Yuk-Ying; Dunaway, R. Gregory

2000-01-01

This article constructs a model to predict the likelihood of parental use of corporal punishment on children in two-parent families. Reports that corporal punishment is primarily determined by cultural, human, and social capital that are available to, or already acquired by parents. Discusses an integrated, resource-based theory for predicting use…

Learning History through the Universal Declaration of Human Rights

ERIC Educational Resources Information Center

Landorf, Hilary; Pineda, Martha Fernanda

2007-01-01

Although adolescent students often do not have knowledge of specific laws, they usually have a keen sense of justice and fairness. In this article, the author discusses the Universal Declaration of Human Rights (UDHR) as a powerful tool to channel students' sense of fairness into visible actions. Adopted in December 1948 by the General Assembly of…

Reflections on J.V. Wertsch's "From Social Interaction to Higher Psychological Processes," "Human Development," 1979

ERIC Educational Resources Information Center

Saxe, Geoffrey B.

2008-01-01

In his 1979 "Human Development" article reprinted in this anniversary issue, James Wertsch presented an approach to genetic analysis of the shifting regulation of problem-solving behavior in early childhood. In my reflections on Wertsch's seminal contribution, I discuss ways that subsequent inquiry built upon ideas he elaborated in the…

Functional and Structural Brain Changes Associated with Methamphetamine Abuse

PubMed Central

Jan, Reem K.; Kydd, Rob R.; Russell, Bruce R.

2012-01-01

Methamphetamine (MA) is a potent psychostimulant drug whose abuse has become a global epidemic in recent years. Firstly, this review article briefly discusses the epidemiology and clinical pharmacology of methamphetamine dependence. Secondly, the article reviews relevant animal literature modeling methamphetamine dependence and discusses possible mechanisms of methamphetamine-induced neurotoxicity. Thirdly, it provides a critical review of functional and structural neuroimaging studies in human MA abusers; including positron emission tomography (PET) and functional and structural magnetic resonance imaging (MRI). The effect of abstinence from methamphetamine, both short- and long-term within the context of these studies is also reviewed. PMID:24961256

Using Watershed Boundaries to Map Adverse Health Outcomes: Examples From Nebraska, USA

PubMed Central

Corley, Brittany; Bartelt-Hunt, Shannon; Rogan, Eleanor; Coulter, Donald; Sparks, John; Baccaglini, Lorena; Howell, Madeline; Liaquat, Sidra; Commack, Rex; Kolok, Alan S

2018-01-01

In 2009, a paper was published suggesting that watersheds provide a geospatial platform for establishing linkages between aquatic contaminants, the health of the environment, and human health. This article is a follow-up to that original article. From an environmental perspective, watersheds segregate landscapes into geospatial units that may be relevant to human health outcomes. From an epidemiologic perspective, the watershed concept places anthropogenic health data into a geospatial framework that has environmental relevance. Research discussed in this article includes information gathered from the literature, as well as recent data collected and analyzed by this research group. It is our contention that the use of watersheds to stratify geospatial information may be both environmentally and epidemiologically valuable. PMID:29398918

Impact of globalization and animal trade on infectious disease ecology.

PubMed

Marano, Nina; Arguin, Paul M; Pappaioanou, Marguerite

2007-12-01

The articles on rabies and Marburg virus featured in this month's Emerging Infectious Diseases (EID) zoonoses issue illustrate common themes. Both discuss zoonotic diseases with serious health implications for humans, and both have a common reservoir, the bat. These articles, and the excitement generated by this year's recognition of World Rabies Day on September 8, also described in this issue, remind us how globalization has had an impact on the worldwide animal trade. This worldwide movement of animals has increased the potential for the translocation of zoonotic diseases, which pose serious risks to human and animal health.

Biotelemetry for Monitoring Electrocardiograms during Athletic Events and Stress Tests

ERIC Educational Resources Information Center

Mitchell, B. W.; Thomasson, G. O.

1975-01-01

This article discusses a study attempting to determine if a biotelemetry system developed for use on chickens could be suitable for monitoring electrocardiograms of humans during exercise. Techniques for its use are reviewed. (JS)

Graduate nurse internship program: a formalized orientation program.

PubMed

Phillips, Tracy; Hall, Mellisa

2014-01-01

The graduate nurse internship program was developed on the basis of Watson's Human Caring Theory. In this article, the author discusses how an orientation program was formalized into an internship program and how the theory was applied.

Natural Disasters and Man-Made Catastrophes

ERIC Educational Resources Information Center

Lonergan, David

2011-01-01

This article categorizes and discusses the kinds of cataclysmic events that threaten the human race and the natural world. A useful set of definitions is provided, and an annotated bibliography of a representative assortment of reference books and monographs.

Ibogaine in the treatment of substance dependence.

PubMed

Brown, Thomas Kingsley

2013-03-01

Ibogaine is a psychoactive alkaloid derived from Tabernanthe iboga, a plant used in initiatory rituals in West Central Africa. Largely because of ibogaine's status as a Schedule I substance in the U.S., the development of ibogaine's use in the treatment of drug addiction took place outside conventional clinical and medical settings. This article reviews the history of ibogaine's use in the treatment of drug addiction, and discusses progress made towards, and obstacles blocking, the establishment of controlled clinical trials of ibogaine's efficacy. Preclinical research has generally supported anecdotal claims that ibogaine attenuates withdrawal symptoms and reduces drug cravings. Concerns about ibogaine's safety, as well as a dearth of solid data from human studies, have hampered progress in its development as an approved medication. This article outlines major findings from preclinical studies, discusses concerns about ibogaine's safety, and details previous and ongoing research on ibogaine's use as an anti-addictive treatment for humans.

Contested embryonic culture in Japan--public discussion, and human embryonic stem cell research in an aging welfare society.

PubMed

Sleeboom-Faulkner, Margaret

2010-01-01

This article explores the reasons for the lack of a broad discussion on bioethical regulation of human embryonic stem cell research (hESR) in Japan and asks why scientists experience difficulties accessing resources for hESR despite the acclaimed indifference of dominant Japanese culture to embryo research. The article shows how various social actors express their views on the embryo and oocyte donation in terms of dominant Japanese culture, foiled against what is regarded as Western culture. Second, it shows how the lack of concern with hESR should be understood in the context of public health policies and communications and bioethics decision making in Japan. Finally, it interprets the meaning of the embryo in the context of Japan as an aging modern welfare society, explaining how policymakers have come to emphasize the urgency of infertility problems over issues around abortion and embryonic life.

Current results with slow freezing and vitrification of the human oocyte.

PubMed

Boldt, Jeffrey

2011-09-01

The past decade has witnessed renewed interest in human oocyte cryopreservation (OCP). This article reviews the two general methods used for OCP, slow freezing and vitrification, compares the outcomes associated with each technique and discusses the factors that might influence success with OCP (such as oocyte selection or day of transfer). Based on available data, OCP offers a reliable, reproducible method for preservation of the female gamete and will find increasing application in assisted reproductive technology. Oocyte cryopreservation can provide a number of advantages to couples undergoing assisted reproduction or to women interested in fertility preservation. Two methods, slow freezing and vitrification, have been used successfully for oocyte cryopreservation. This article reviews and compares these methods, and discusses various factors that can impact upon success of oocyte cryopreservation. Copyright © 2011 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

Regulations and Ethical Considerations for Astronomy Education Research II: Resources and Worked Examples

NASA Astrophysics Data System (ADS)

Brogt, Erik; Dokter, Erin; Antonellis, Jessie; Buxner, Sanlyn

This article discusses the legal and ethical requirements of human subjects research proposals in astronomy education research. We present an overview of the relevant laws, regulations, and guidelines that inform an Institutional Review Board evaluation of proposed research. We also present examples of potential research projects in astronomy education research and discuss their ethical issues.

The overview effect: the impact of space exploration on the evolution of nursing science.

PubMed

Butcher, H K; Forchuk, C

1992-01-01

The purpose of this article is to explore the overview effect, an experience evoked by space travel that has the capacity to transform all patterns of human existence and evolution toward greater potentials in human diversity and creativity. As nurses migrate with humanity into the solar system and beyond, they will experience the overview effect. The core components of the effect include changed perceptions of space, time, sound, and weight which have the potential to transform the evolution of nursing science. Nursing paradigms will encompass a view of humanity as integral with an infinite evolutionary universe. After generations of living in space in a diversity of new environments, the physical body will undergo radical changes, and the meaning of health will be transformed. The article concludes with a discussion on the parallels between Rogers' science of unitary human beings and the overview effect.

Reflections on Mental Retardation and Eugenics, Old and New: Mensa and the Human Genome Project.

ERIC Educational Resources Information Center

Smith, J. David

1994-01-01

This article addresses the moral and ethical issues of mental retardation and a continuing legacy of belief in eugenics. It discusses the involuntary sterilization of Carrie Buck in 1927, support for legalized killing of subnormal infants by 47% of respondents to a Mensa survey, and implications of the Human Genome Project for the field of mental…

The Search for Better Ways of Speaking about Culture, Identity and Values

ERIC Educational Resources Information Center

Pearce, Richard

2014-01-01

This article aims to provide better metaphors for thinking and speaking about culture, identity and values. In terms of human behaviour, the words culture, identity and values are viewed as useful reifications which have allowed us to discuss human action in terms of nouns. However, the terms have been used over many years in various theoretical…

Antimicrobial Resistance in Agriculture

PubMed Central

Thanner, Sophie; Drissner, David

2016-01-01

ABSTRACT In this article, the current knowledge and knowledge gaps in the emergence and spread of antimicrobial resistance (AMR) in livestock and plants and importance in terms of animal and human health are discussed. Some recommendations are provided for generation of the data required in order to develop risk assessments for AMR within agriculture and for risks through the food chain to animals and humans. PMID:27094336

Concept Mapping in the Humanities to Facilitate Reflection: Externalizing the Relationship between Public and Personal Learning

ERIC Educational Resources Information Center

Kandiko, Camille; Hay, David; Weller, Saranne

2013-01-01

This article discusses how mapping techniques were used in university teaching in a humanities subject. The use of concept mapping was expanded as a pedagogical tool, with a focus on reflective learning processes. Data were collected through a longitudinal study of concept mapping in a university-level Classics course. This was used to explore how…

[Characteristics of some Arctic cities according to data of physiologic and hygienic evaluation of the influence of weather and climate on human thermoregulation].

PubMed

Kaptsov, V A; Ratner, E M

1996-01-01

The article presents an original approach to evaluation of climate and weather according to their influence of human heat state. Use of the approach is accompanied by climate characteristics of some Transpolar cities, the authors discuss application of those characteristics to solution of hygienic problems.

General Climatology 3

NASA Astrophysics Data System (ADS)

Hartmann, Dennis L.

General Climatology 3 is volume 3 of the series World Survey of Climatology, which consists of 15 volumes containing review articles on a broad range of topics. General Climatology 3 contains four chapters: ‘Human Bioclimatology,’ ‘Agricultural Climatology,’ ‘City Climate,’ and ‘Technical Climatology.’ Each of these chapters will be briefly described here.‘Human Bioclimatology,’ the first chapter, was authored by E. Flach and provides a survey of the effects on the human organism of the physical conditions at the earth's surface. It contains four main sections. A section entitled ‘Light and Life’ deals with the effects of solar radiation on man and contains much interesting information on the response of the human eye and human skin to radiation at various frequencies. ‘Air and Life’ discusses the composition of air and its effect on human health and performance, including discussions of the effects of altitude, aerosols, and noxious trace gases. ‘Temperature and Life’ discusses how the body responds to temperature and how it maintains its heat budget under the variety of conditions to which it falls subject and considerable discussion is given to objective ways to characterize air conditions that give an accurate measure of their impact on the body. This discussion leads naturally into the final section, ‘Bioclimatological Evaluation Systems,’ which addresses the problem of how to classify a particular site according to its overall suitability to human habitation.

Cancer pain and current theory for pain control.

PubMed

Kahan, Brian

2014-05-01

This article discusses current trends in managing cancer pain, with specific regard to opioid transmission, descending pathway inhabitation, and ways to facilitate the endogenous antinociceptive chemicals in the human body. Various techniques for opioid and nonopioid control of potential pain situations of patients with cancer are discussed. The benefits of using pharmacogenetics to assess the appropriate medications are addressed. Finally, specific treatment of abdominal cancer pain using radiofrequency lesioning is discussed. Copyright © 2014 Elsevier Inc. All rights reserved.

Overview of spaceflight immunology studies

NASA Technical Reports Server (NTRS)

Taylor, G. R.

1993-01-01

The effects of spaceflight and analogues of spaceflight are discussed here and in nine accompanying articles. In this summary we present spaceflight studies with human subjects, animal subjects, and cell cultures and we review ground-based systems used to model the observed effects of spaceflight on the immune system. Human paradigms include bed rest, academic or psychological stress, physical stress, hypobaric or high altitude stress, and confinement. Animal models include antiorthostatic and orthostatic suspension, hypobarism, and confinement. The ten manuscripts in this collection were selected to provide a summary that should give the reader an overview of the various activities of spaceflight immunology researchers throughout the history of space travel. This manuscript identifies the major contributors to the study of spaceflight immunology, explains what types of studies have been conducted, and how they have changed over the years. Also presented is a discussion of the unusual limitations associated with spaceflight research and the efforts to develop appropriate ground-based surrogate model systems. Specific details, data, and mechanistic speculations will be held to a minimum, because they will be discussed in depth in the other articles in the collection.

The Management of isiZulu as a Language of Teaching and Learning at the University of KwaZulu-Natal's College of Humanities

ERIC Educational Resources Information Center

Ndebele, Hloniphani; Zulu, Nogwaja S.

2017-01-01

Over the past few decades, there has been an increased awareness of the strategic role of indigenous African languages in multilingual South Africa. This article discusses the strategic role that indigenous languages could and should play in the promotion of multilingual South Africa. The article pays attention to bilingual education and the…

The Sense-Appeal Approach

ERIC Educational Resources Information Center

Shoneman, Anne

1977-01-01

Using a classroom discussion of the human digestive system as an example, the article promotes the idea that demonstrating abstractions in concrete experiential terms permits the learning disabled youngster to discover concepts for himself, which is the best possible learning experience. (JYC)

What's Ahead for 1990?

ERIC Educational Resources Information Center

Platt, John

1973-01-01

New patterns of politics, rights, and human relations are surveyed in this article about life in the future. Discusses ways in which technological advancement is changing education, work, and public health. The dilemma between planning and decentralization in government is also considered. (DN)

Artificial intelligence: Learning to play Go from scratch

NASA Astrophysics Data System (ADS)

Singh, Satinder; Okun, Andy; Jackson, Andrew

2017-10-01

An artificial-intelligence program called AlphaGo Zero has mastered the game of Go without any human data or guidance. A computer scientist and two members of the American Go Association discuss the implications. See Article p.354

Deadly medicine.

PubMed

Bachrach, Susan

2007-01-01

This article discusses the methods the United States Holocaust Memorial Museum used to make an exhibition on the complex history of Nazi eugenics accessible to the museum's mass public and at the same time, provocative for special audiences consisting of professionals and students from the biomedical fields. Deadly Medicine: Creating the Master Race showed how both eugenics and related "euthanasia" programs in Nazi Germany helped pave the road to the Holocaust. The exhibition implicitly evoked the present-day appeal of biological explanations for human behavior and of new visions of human perfection. Educational programs used the exhibition as a springboard for discussions of bioethics and medical ethics.

When synthetic chemicals degrade in the environment: What are the absolute fate, effects, and potential risks to humans and the ecosystem?

USGS Publications Warehouse

Boxall, Alistair; Sinclair, C.; Fenner, Kathrin; Kolpin, Dana W.; Maund, S.

2004-01-01

Although some regulatory schemes require information about the impacts of degradates on human and environmental health, that information does not exist for many compounds (25, 26). Pesticides are the exception. In this article, we bring together the available data to address the environmental behavior of degradates and their effects on organisms and discuss how to identify substances of potential concern. In addition, we cite gaps in the current knowledge and make recommendations for future research requirements. While the article focuses on pesticides, we believe these observations can be extended to biologically active compounds and some industrial substances.

[Multifaceted body. I. The bodies of medicine].

PubMed

Saraga, M; Bourquin, C; Wykretowicz, H; Stiefel, F

2015-02-11

The human body is the object upon which medicine is acting, but also lived reality, image, symbol, representation and the object of elaboration and theory. All these elements which constitute the body influence the way medicine is treating it. In this series of three articles, we address the human body from various perspectives: medical (1), phenomenological (2), psychosomatic and socio-anthropological (3). This first article discusses four distinct types of representation of the body within medicine, each related to a specific epistemology and shaping a distinct kind of clinical legitimacy: the body-object of anatomy, the body-machine of physiology, the cybernetic body of biology, the statistical body of epidemiology.

Changing undergraduate human anatomy and physiology laboratories: perspectives from a large-enrollment course.

PubMed

Griff, Edwin R

2016-09-01

In the present article, a veteran lecturer of human anatomy and physiology taught several sections of the laboratory component for the first time and shares his observations and analysis from this unique perspective. The article discusses a large-enrollment, content-heavy anatomy and physiology course in relationship to published studies on learning and student self-efficacy. Changes in the laboratory component that could increase student learning are proposed. The author also points out the need for research to assess whether selective curricular changes could increase the depth of understanding and retention of learned material. Copyright © 2016 The American Physiological Society.

Preoperative steroids for hearing preservation cochlear implantation: A review.

PubMed

Kuthubutheen, Jafri; Smith, Leah; Hwang, Euna; Lin, Vincent

2016-01-01

Preoperative steroids have been shown to be beneficial in reducing the hearing loss associated with cochlear implantation. This review article discusses the mechanism of action, effects of differing routes of administration, and side effects of steroids administered to the inner ear. Studies on the role of preoperative steroids in animal and human studies are also examined and future directions for research in this area are discussed.

An evidence-based approach to organization evaluation and change in human service organizations evaluation and program planning.

PubMed

Schalock, Robert L; Lee, Tim; Verdugo, Miguel; Swart, Kees; Claes, Claudia; van Loon, Jos; Lee, Chun-Shin

2014-08-01

The work described in this article focuses primarily on how human service organizations can use an evidence-based, self-assessment approach to organization evaluation to facilitate continuous quality improvement and organization change. Real-life examples are presented, strengths and challenges discussed, and future conceptual and measurement issues identified. Copyright © 2014 Elsevier Ltd. All rights reserved.

Five Reasons to Put the "g" Back into Giftedness: An Argument for Applying the Cattell-Horn-Carroll Theory of Intelligence to Gifted Education Research and Practice

ERIC Educational Resources Information Center

Warne, Russell T.

2016-01-01

Human intelligence (also called general intelligence, "g," or Spearman's "g") is a highly useful psychological construct. Yet, since the middle of the 20th century, gifted education researchers have been reluctant to discuss human intelligence. The purpose of this article is to persuade gifted education researchers and…

Patent eligibility of stem cells in Europe: where do we stand after 8 years of case law?

PubMed

Storz, Ulrich; Faltus, Timo

2017-01-01

Since 2006, some of the highest ranking European Courts have issued decisions related to the patent eligibility of human embryonic stem cells. The question of patent eligibility of human embryonic stem cells remains, however, still erratic, at least in some aspects. This article will give a short comprehensive overview of the case history, and discuss questions still unsolved.

THE SRI CHAKRA AS A SYMBOL OF THE HUMAN BODY

PubMed Central

Krishnakumar, P.R.

1993-01-01

Sri Chakra is the celebrated Yantra used in the worship of the primordial energy. The Chakra is conceived as a symbol of the human body. Some salient features of this symbolism are discussed in this article. An attempt has also been made to provide a short introduction to the Bhavanopanishad Prayogavidhi devised by Bhaskararaya, the doyen of Sri charka worshippers. PMID:22556608

Building "Special Capital" for Entrepreneurial Development: Special Populations as Human Capital in the Context of Global Development

ERIC Educational Resources Information Center

Walker, Gabriela

2010-01-01

Ten to twelve percent of the world population is identified as having one or more types of disability. This ecodeme has been historically known to be discriminated, marginalized, and disempowered by the lack of access to resources and to education. This article discusses the importance of adding special capital to the global human capital in the…

Neuropeptide Regulation of Social Attachment: The Prairie Vole Model

PubMed Central

Tabbaa, Manal; Paedae, Brennan; Liu, Yan; Wang, Zuoxin

2016-01-01

Social attachments are ubiquitous among humans and integral to human health. Although great efforts have been made to elucidate the neural underpinnings regulating social attachments, we still know relatively little about the neuronal and neurochemical regulation of social attachments. As a laboratory animal research model, the socially monogamous prairie vole (Microtus ochrogaster) displays behaviors paralleling human social attachments and thus has provided unique insights into the neural regulation of social behaviors. Research in prairie voles has particularly highlighted the significance of neuropeptidergic regulation of social behaviors, especially of the roles of oxytocin (OT) and vasopressin (AVP). This article aims to review these findings. We begin by discussing the role of the OT and AVP systems in regulating social behaviors relevant to social attachments, and thereafter restrict our discussion to studies in prairie voles. Specifically, we discuss the role of OT and AVP in adult mate attachments, biparental care, social isolation, and social buffering as informed by studies utilizing the prairie vole model. Not only do these studies offer insight into social attachments in humans, but they also point to dysregulated mechanisms in several mental disorders. We conclude by discussing these implications for human health. PMID:28135000

What neuropsychology tells us about human tool use? The four constraints theory (4CT): mechanics, space, time, and effort.

PubMed

Osiurak, François

2014-06-01

Our understanding of human tool use comes mainly from neuropsychology, particularly from patients with apraxia or action disorganization syndrome. However, there is no integrative, theoretical framework explaining what these neuropsychological syndromes tell us about the cognitive/neural bases of human tool use. The goal of the present article is to fill this gap, by providing a theoretical framework for the study of human tool use: The Four Constraints Theory (4CT). This theory rests on two basic assumptions. First, everyday tool use activities can be formalized as multiple problem situations consisted of four distinct constraints (mechanics, space, time, and effort). Second, each of these constraints can be solved by the means of a specific process (technical reasoning, semantic reasoning, working memory, and simulation-based decision-making, respectively). Besides presenting neuropsychological evidence for 4CT, this article shall address epistemological, theoretical and methodological issues I will attempt to resolve. This article will discuss how 4CT diverges from current cognitive models about several widespread hypotheses (e.g., notion of routine, direct and automatic activation of tool knowledge, simulation-based tool knowledge).

The Brain.

ERIC Educational Resources Information Center

Hubel, David H.

1979-01-01

This article on the brain is part of an entire issue about neurobiology and the question of how the human brain works. The brain as an intricate tissue composed of cells is discussed based on the current knowledge and understanding of its composition and structure. (SA)

The Ways We Serve.

ERIC Educational Resources Information Center

Leonard, Gloria; And Others

1991-01-01

Four articles discuss library services to diverse user groups. Highlights include the Seattle Public Library's Human Diversity Training Program for library staff; cultural diversity at the University of Northern Colorado, including library collection development; information needs of physicists in special libraries; and library services to…

Discussions of Adolescent Sexuality in News Media Coverage of the HPV Vaccine

PubMed Central

Casciotti, Dana M.; Smith, Katherine C.; Tsui, Amy

2017-01-01

Given the sexually transmitted nature of human papillomavirus (HPV), some worry the HPV vaccine will create a false sense of security and promote adolescent sexual activity. Media coverage of vaccines can influence social norms, parental attitudes, and vaccine acceptance; in this paper we examine U.S. news media messages related to sexuality and HPV vaccination. Drawing on a structured analysis of 447 articles published during 2005-2009, we qualitatively analyzed a purposive sample of 49 articles discussing adolescent health behaviors related to HPV vaccination. Commonly, articles discussed vaccination in the context of abstinence-only versus comprehensive sexual health education; cited research findings to support vaccination or sex education; argued against connecting vaccination to promiscuous behavior; but included fear-inducing messages. Media messages concerning health behaviors related to HPV vaccination tended to support government and parental involvement in sex education, and dismiss concerns linking vaccination to sexual activity, while also presenting the vaccine as lifesaving. PMID:24439619

Discussions of adolescent sexuality in news media coverage of the HPV vaccine.

PubMed

Casciotti, Dana M; Smith, Katherine C; Tsui, Amy; Klassen, Ann C

2014-02-01

Given the sexually transmitted nature of human papillomavirus (HPV), some worry the HPV vaccine will create a false sense of security and promote adolescent sexual activity. Media coverage of vaccines can influence social norms, parental attitudes, and vaccine acceptance; in this paper we examine U.S. news media messages related to sexuality and HPV vaccination. Drawing on a structured analysis of 447 articles published during 2005-2009, we qualitatively analyzed a purposive sample of 49 articles discussing adolescent health behaviors related to HPV vaccination. Commonly, articles discussed vaccination in the context of abstinence-only versus comprehensive sexual health education; cited research findings to support vaccination or sex education; argued against connecting vaccination to promiscuous behavior; but included fear-inducing messages. Media messages concerning health behaviors related to HPV vaccination tended to support government and parental involvement in sex education, and dismiss concerns linking vaccination to sexual activity, while also presenting the vaccine as lifesaving. Copyright © 2013 The Foundation for Professionals in Services for Adolescents. All rights reserved.

Print and online newspaper coverage of the link between HPV and oral cancer in the UK: a mixed-methods study

PubMed Central

Dodd, Rachael H; Marlow, Laura A V; Forster, Alice S; Waller, Jo

2016-01-01

Objectives The role of human papillomavirus (HPV) in some oral cancers has been reported in the news press, though little is known about the content of these articles. This study aimed to examine how frequently the link between HPV and oral cancer has been reported in the news press and to examine the content of these articles. Design UK media articles were searched for articles relating to oral cancer and HPV in the database NexisUK. Of 854 articles identified by the initial search, 112 were eligible for inclusion (2002–2014) and content analysis was used to determine the main themes discussed. Results Themes included actor Michael Douglas’ claim that his throat cancer was caused by HPV, the riskiness of oral sex, health information (including HPV as a cause of oral cancer) and the need to vaccinate boys against HPV. Many articles also referred to the link between HPV and cervical cancer and the increasing incidence of HPV-related oral cancer. The largest peak in articles occurred when Michael Douglas discussed his cancer (June 2013). Facts about HPV and references to research were provided in some articles. Conclusions The link between HPV and oral cancer and the transmission of HPV via oral sex was regularly discussed, yet coverage often lacked detailed health information. This could increase awareness of the link between oral sex and HPV risk, but may also lead to public concern about oral sex as a sexual behaviour. PMID:26920439

Resurgence of vitamin D: Old wine in new bottle

PubMed Central

Vaishya, Raju; Vijay, Vipul; Agarwal, Amit Kumar; Jahangir, Jabed

2015-01-01

There are early references of it in ancient text and physicians have discussed its importance and features of its deficiency in the past. Vitamin D has again regained interest with recent dramatic rise in the incidence of deficiency in the developing as well as developing world. In this review article, we discuss the biochemical and role of vitamin D in the skeletal system. We also discuss the recommended dietary requirements and features of skeletal deficiency. Extra-skeletal roles of vitamin D deficiency have been a matter of debate lately and it has also been discussed in detail in this article. In conclusion, it would not be wrong to label vitamin D as one of the most important vitamin involved in the metabolism of the musculoskeletal system and any clinician, especially the orthopaedician, should be well versed with its overall mechanism and roles in the human body. PMID:26155053

[Effect of oxytocin on human pain perception].

PubMed

Pfeifer, A-C; Ditzen, B; Neubauer, E; Schiltenwolf, M

2016-10-01

Over the years the effect of the neuropeptide oxytocin and its possible utilization for pain management has been increasingly more investigated and discussed. Initial results emphasized the effects of oxytocin with respect to labor and breastfeeding. Diverse animals studies were also able to demonstrate the effectiveness of the peptide in attachment behavior and pain perception; however, it is still unclear how oxytocin affects pain perception in humans. The potential therapeutic effectiveness of oxytocin could be particularly important for primary and secondary treatment of pain patients because chronification of pain can occur more frequently in this area. For this review the databases PubMed, Medline und PsycINFO were searched using the terms oxytocin, pain, human and analgesic. The search resulted in a total of 89 original articles after excluding articles regarding labor pain, breastfeeding and animal studies. Only those studies were included which were carried out between 1994 and 2015. A total of 17 articles remained for inclusion in this review and included 13 studies on the exogenous application of oxytocin and 4 on measurement of oxytocin levels in plasma. This review article gives a summary of the current state of research on oxytocin and its direct and indirect association with human pain perception and emphasizes its relevance for the multimodal management of pain.

The Trainer As Machiavelli

ERIC Educational Resources Information Center

Bell, Chip R.

1976-01-01

The article views power as a potential tool for human resource development (HRD) practitioners and focuses on personal power (the ability to influence others) rather than on role power (the right to influence others). Manipulation is discussed as a way to exercise personal power. (Author/BP)

Strategic Human Resources Management of Employer Cooperative Education Programs.

ERIC Educational Resources Information Center

Nielsen, Richard P.; Porter, Ralph C.

1982-01-01

This article discusses effective strategic planning and management of employer cooperative education programs. It examines types of planning, the need for such programs, and implementation strategies. Several case studies are considered: Dayton-Hudson, IBM, AT&T, Delta Airlines, and Rockwell International. (CT)

The Human Response to Library Automation.

ERIC Educational Resources Information Center

Kirkland, Janice, Ed.

1989-01-01

Eleven articles discuss the response of library users and personnel to automation. Topics covered include computerized reference services, online public access catalogs, paraprofessional staff perceptions of technology, organizational and managerial impacts of automation, workshops on new technology, gender differences in motivation to manage and…

Artificial Intelligence--Applications in Education.

ERIC Educational Resources Information Center

Poirot, James L.; Norris, Cathleen A.

1987-01-01

This first in a projected series of five articles discusses artificial intelligence and its impact on education. Highlights include the history of artificial intelligence and the impact of microcomputers; learning processes; human factors and interfaces; computer assisted instruction and intelligent tutoring systems; logic programing; and expert…

Performance, Performance System, and High Performance System

ERIC Educational Resources Information Center

Jang, Hwan Young

2009-01-01

This article proposes needed transitions in the field of human performance technology. The following three transitions are discussed: transitioning from training to performance, transitioning from performance to performance system, and transitioning from learning organization to high performance system. A proposed framework that comprises…

Climate change and public health policy: translating the science.

PubMed

Braks, Marieta; van Ginkel, Rijk; Wint, William; Sedda, Luigi; Sprong, Hein

2013-12-19

Public health authorities are required to prepare for future threats and need predictions of the likely impact of climate change on public health risks. They may get overwhelmed by the volume of heterogeneous information in scientific articles and risk relying purely on the public opinion articles which focus mainly on global warming trends, and leave out many other relevant factors. In the current paper, we discuss various scientific approaches investigating climate change and its possible impact on public health and discuss their different roles and functions in unraveling the complexity of the subject. It is not our objective to review the available literature or to make predictions for certain diseases or countries, but rather to evaluate the applicability of scientific research articles on climate change to evidence-based public health decisions. In the context of mosquito borne diseases, we identify common pitfalls to watch out for when assessing scientific research on the impact of climate change on human health. We aim to provide guidance through the plethora of scientific papers and views on the impact of climate change on human health to those new to the subject, as well as to remind public health experts of its multifactorial and multidisciplinary character.

Climate Change and Public Health Policy: Translating the Science

PubMed Central

Braks, Marieta; van Ginkel, Rijk; Wint, William; Sedda, Luigi; Sprong, Hein

2013-01-01

Public health authorities are required to prepare for future threats and need predictions of the likely impact of climate change on public health risks. They may get overwhelmed by the volume of heterogeneous information in scientific articles and risk relying purely on the public opinion articles which focus mainly on global warming trends, and leave out many other relevant factors. In the current paper, we discuss various scientific approaches investigating climate change and its possible impact on public health and discuss their different roles and functions in unraveling the complexity of the subject. It is not our objective to review the available literature or to make predictions for certain diseases or countries, but rather to evaluate the applicability of scientific research articles on climate change to evidence-based public health decisions. In the context of mosquito borne diseases, we identify common pitfalls to watch out for when assessing scientific research on the impact of climate change on human health. We aim to provide guidance through the plethora of scientific papers and views on the impact of climate change on human health to those new to the subject, as well as to remind public health experts of its multifactorial and multidisciplinary character. PMID:24452252

Connections Between Science and Spirituality

NASA Astrophysics Data System (ADS)

Garen, David C.

2006-07-01

I would like to continue the discussion ofpoints raised in William Carter's response toRobert Frodeman's Eos Forum article Carter,2006; Frodeman, 2005. I have appreciatedFrodeman's work and feel that perspectiveson science deriving from humanities, philosophy,and religion can add depth, insight,and meaning to our endeavors. I would liketo broaden the discussion beyond just spacepolicy to include the relationship betweenscience in general and these, what I wouldcall, spiritual issues.

"Wherever You Go, You Will Be a Polis": Spatial Practices and Political Education in Computer-Supported Collaborative Learning Discussions

ERIC Educational Resources Information Center

Slakmon, Benzi; Schwarz, Baruch B.

2017-01-01

The aim of this article is to increase understanding of the development of spatial practices in virtual learning environments. The spatial change and development in 38 small-group e-discussions taken from a data set of a yearlong 8th-grade humanities course are described and analyzed. We show that the focus on spatial changes in computer-supported…

Human organomics: a fresh approach to understanding human development using single-cell transcriptomics.

PubMed

Camp, J Gray; Treutlein, Barbara

2017-05-01

Innovative methods designed to recapitulate human organogenesis from pluripotent stem cells provide a means to explore human developmental biology. New technologies to sequence and analyze single-cell transcriptomes can deconstruct these 'organoids' into constituent parts, and reconstruct lineage trajectories during cell differentiation. In this Spotlight article we summarize the different approaches to performing single-cell transcriptomics on organoids, and discuss the opportunities and challenges of applying these techniques to generate organ-level, mechanistic models of human development and disease. Together, these technologies will move past characterization to the prediction of human developmental and disease-related phenomena. © 2017. Published by The Company of Biologists Ltd.

On the Way into the Bologna Reform--A Consideration of the Quality and the Role of Human Resource Management in Higher Education System

ERIC Educational Resources Information Center

Kohont, Andrej; Nadoh Bergoc, Jana

2010-01-01

In the article the concept of higher education quality is discussed, putting an emphasis on the concept of quality as a transformation. In this context the teachers are stimulated to use contemporary teaching/learning tools and to take active role in the development and empowerment of learners. The role of human resource management (HRM) is also…

Exploring School Ethos: An Investigation of Children's Human Rights in Two Secondary Institutions in Hong Kong

ERIC Educational Resources Information Center

Lo, Yan Lam; Leung, Yan Wing; Yuen, Wai Wa

2015-01-01

From 2009 to 2011, the authors launched the Basic Law Education Project: Education for Human Rights and the Rule of Law in Hong Kong. This article focuses on a subset of the overarching data-set and discusses the findings that resulted from a comparative analysis of two participating schools. A survey was deployed to assess the extent to which a…

Divergent fates of the medical humanities in psychiatry and internal medicine: should psychiatry be rehumanized?

PubMed

Rutherford, Bret R; Hellerstein, David J

2008-01-01

To determine the degree to which the medical humanities have been integrated into the fields of internal medicine and psychiatry, the authors assessed the presence of medical humanities articles in selected psychiatry and internal medicine journals from 1950 to 2000. The journals searched were the three highest-ranking psychiatry and internal medicine journals on the Institute for Scientific Information's Impact Factor rankings that were published in English and aimed at a clinical audience. Operationalized criteria defining the medical humanities allowed the percentage of text in the selected journals constituting medical humanities to be quantified. Journals were hand searched at 10-year intervals from 1950 to 2000. Mixed effects models were used to describe the change in medical humanities over time. The percentage of text within psychiatry journals meeting the criteria for medical humanities declined from a peak of 17% in 1970 to a low of 2% in 2000, while the percentage of humanities articles in internal medicine journals roughly doubled from 5% to 11% over the same time period. A linear model increasing over time best fit the medical humanities in the internal medicine journals, while a cubic model decreasing over time best fit the psychiatry humanities data. Humanities articles in medical journals had a greater breadth and diversity than those in psychiatry journals. Medical humanities publications dramatically decreased over time in psychiatry journals while they more than doubled in internal medicine journals. These data suggest the need for further empirical research and discussion of the potential roles of the humanities in psychiatry.

Framing global health: the governance challenge.

PubMed

McInnes, Colin; Kamradt-Scott, Adam; Lee, Kelley; Reubi, David; Roemer-Mahler, Anne; Rushton, Simon; Williams, Owain David; Woodling, Marie

2012-01-01

With the emergence of global health comes governance challenges which are equally global in nature. This article identifies some of the initial limitations in analyses of global health governance (GHG) before discussing the focus of this special supplement: the framing of global health issues and the manner in which this impacts upon GHG. Whilst not denying the importance of material factors (such as resources and institutional competencies), the article identifies how issues can be framed in different ways, thereby creating particular pathways of response which in turn affect the potential for and nature of GHG. It also identifies and discusses the key frames operating in global health: evidence-based medicine, human rights, security, economics and development.

Sinanthropus in Britain: human origins and international science, 1920-1939.

PubMed

Manias, Chris

2015-06-01

The Peking Man fossils discovered at Zhoukoudian in north-east China in the 1920s and 1930s were some of the most extensive palaeoanthropological finds of the twentieth century. This article examines their publicization and discussion in Britain, where they were engaged with by some of the world's leading authorities in human evolution, and a media and public highly interested in human-origins research. This international link - simultaneously promoted by scientists in China and in Britain itself - reflected wider debates on international networks; the role of science in the modern world; and changing definitions of race, progress and human nature. This article illustrates how human-origins research was an important means of binding these areas together and presenting scientific work as simultaneously authoritative and credible, but also evoking mystery and adventurousness. Examining this illustrates important features of contemporary views of both science and human development, showing not only the complexities of contemporary regard for the international and public dynamics of scientific research, but wider concerns over human nature, which oscillated between optimistic notions of unity and progress and pessimistic ones of essential differences and misdirected development.

ERM Ideas and Innovations: Digital Repository Management as ERM

ERIC Educational Resources Information Center

Pinkas, María M.; Lin, Na

2014-01-01

This article describes the application of electronic resources management (ERM) to digital repository management at the Health Sciences and Human Services Library at the University of Maryland, Baltimore. The authors discuss electronic resources management techniques, through the application of "Techniques for Electronic Management,"…

Everyday Ethics: Reflections on Practice

ERIC Educational Resources Information Center

Rossman, Gretchen B.; Rallis, Sharon F.

2010-01-01

This introductory article frames the contributions for this issue on everyday ethics--moments that demand moral considerations and ethical choices that researchers encounter. We discuss concerns raised within the research community about the tendency to observe merely obligatory ethical procedures as outlined in Human Subjects Review regulations.…

From the Shop Floor to the Executive Suite.

ERIC Educational Resources Information Center

Lemons, William L.

1985-01-01

Describes the Productivity Group, created by the Oklahoma State Department of Vocational and Technical Education. The Group boosts small businesses by making available quality management development programs and human resource consulting services. The article discusses program management, costs, and the business community's response. (CT)

Cocaine Use among the College Age Group: Biological and Psychological Effects--Clinical and Laboratory Research Findings.

ERIC Educational Resources Information Center

Nicholi, Armand M., Jr.

1984-01-01

Knowledge about cocaine's effect on the human mind and body is limited and not clearly documented. This article discusses various biological and psychological effects of the drug based on clinical and laboratory studies of man. (Author/DF)

Library+

ERIC Educational Resources Information Center

Merrill, Alex

2011-01-01

This article discusses possible future directions for academic libraries in the post Web/Library 2.0 world. These possible directions include areas such as data literacy, linked data sets, and opportunities for libraries in support of digital humanities. The author provides a brief sketch of the background information regarding the topics and…

Education and the Religious.

ERIC Educational Resources Information Center

Vandenberg, Donald

1987-01-01

This article attempts to emancipate the religious aspect of human existence from its accidental, historical embodiment in religions. The religious concerns being at home in nature, on earth, and in the universe. Ways of teaching this natural piety in a manner not connected with religion are discussed. (MT)

Marine Biology and Human Affairs

ERIC Educational Resources Information Center

Russell, F. S.

1976-01-01

Marine biology has become an important area for study throughout the world. The author of this article discusses some of the important discoveries and fields of research in marine biology that are useful for mankind. Topics include food from the sea, fish farming, pesticides, pollution, and conservation. (MA)

The Legacy of Robert M. Gagne.

ERIC Educational Resources Information Center

Richey, Rita C., Ed.

This book highlights and discusses the contributions of Robert M. Gagne to the field of instructional technology. Section One presents the core concepts of Gagne's theory and contains reprints of the following five journal articles by Gagne: "Contributions of Learning to Human Development,""Learning Hierarchies,""Domains…

Performing Resistance

ERIC Educational Resources Information Center

Garoian, Charles R.; Gaudelius, Yvonne M.

2004-01-01

Many contemporary artists, critical theorists, and educators challenge the cultural assumptions that are embedded in our understandings of technology and its relationship to art, the body, and human life. In this article, we discuss the performance artworks of osseus labyrint, Goat Island, and Guillermo Gomez-Pena, Roberto Sifuentes, and Juan…

Genes and Syndromic Hearing Loss.

ERIC Educational Resources Information Center

Keats, Bronya J. B.

2002-01-01

This article provides a description of the human genome and patterns of inheritance and discusses genes that are associated with some of the syndromes for which hearing loss is a common finding, including: Waardenburg, Stickler, Jervell and Lange-Neilsen, Usher, Alport, mitochondrial encephalomyopathy, and sensorineural hearing loss. (Contains…

Llama handling and training.

PubMed

McGee, M

1994-07-01

This article offers insights into the relationship of llama owners to their animals and the role of veterinarians as part of the animal care team. The effect of human behavior and handling techniques on llama behavior and marketability are discussed. Progressive ideas for nonforceful llama handling equipment, procedures, and training ideas are outlined in detail. Included are specific training plans for routine herd management chores such as injections and toenail trimming. This article is useful for both veterinarians and llama owners.

Forensic DNA testing.

PubMed

Butler, John M

2011-12-01

Forensic DNA testing has a number of applications, including parentage testing, identifying human remains from natural or man-made disasters or terrorist attacks, and solving crimes. This article provides background information followed by an overview of the process of forensic DNA testing, including sample collection, DNA extraction, PCR amplification, short tandem repeat (STR) allele separation and sizing, typing and profile interpretation, statistical analysis, and quality assurance. The article concludes with discussions of possible problems with the data and other forensic DNA testing techniques.

Encountering science education's capacity to affect and be affected

NASA Astrophysics Data System (ADS)

Alsop, Steve

2016-09-01

What might science education learn from the recent affective turn in the humanities and social sciences? Framed as a response to Michalinos Zembylas's article, this essay draws from selected theorizing in affect theory, science education and science and technology studies, in pursuit of diverse and productive ways to talk of affect within science education. These discussions are framed by desires to transcend traditional epistemic boundaries and practices. The article concludes offering some associated ambiguities and tensions involved.

Human genetic technology: who shall control?

PubMed

Blank, R H

1984-01-01

The biotechnical "revolution" has fast come upon us. It promises to produce both substantial benefits and difficult dilemmas for individuals and society. Despite the growing attention being paid to biotechnology, a major unanswered question is who shall control the development and use of the powerful array of human genetic and reproductive innovations. Should the decisions be left to individual consumers and private industry or should they be made by the government or other social institutions? After briefly reviewing development in human genetics and reproduction and describing trends toward commercialization of them, this article discusses the dilemmas these trends raise for a democratic society. It argues for the urgent need to delineate societal goals and priorities for the future and for technology assessment as early as possible in the developmental process. The article concludes by presenting some examples of the social policy problems now emerging.

Therapeutic and reproductive cloning: a critique.

PubMed

Bowring, Finn

2004-01-01

This article is a critical examination of the science and ethics of human cloning. It summarises the key scientific milestones in the development of nuclear transplantation, explains the importance of cloning to research into the medical potential of embryonic stem cells, and discusses the well-worn distinction between 'therapeutic' and 'reproductive' cloning. Suggesting that this distinction will be impossible to police, it goes on to consider the ethics of full human cloning. It is concluded that it represents an unacceptable form of parental despotism, and that the genetic engineering and cloning of future human beings will fracture the foundations of modern humanism.

Recent advances in the use of ZFN-mediated gene editing for human gene therapy.

PubMed

Chandrasegaran, Srinivasan

2017-01-01

Targeted genome editing with programmable nucleases has revolutionized biomedical research. The ability to make site-specific modifications to the human genome, has invoked a paradigm shift in gene therapy. Using gene editing technologies, the sequence in the human genome can now be precisely engineered to achieve a therapeutic effect. Zinc finger nucleases (ZFNs) were the first programmable nucleases designed to target and cleave custom sites. This article summarizes the advances in the use of ZFN-mediated gene editing for human gene therapy and discusses the challenges associated with translating this gene editing technology into clinical use.

A human rights framework for midwifery care.

PubMed

Thompson, Joyce Beebe

2004-01-01

This article presents a rights-based model for midwifery care of women and childbearing families. Salient features include discussion of the influence of values on how women are viewed within cultures and societies, universal ethical principles applicable to health care services, and human rights based on the view of women as persons rather than as objects or chattel. Examples of the health impact on women of persistent violation of basic human rights are used to support the need for using a human rights framework for midwifery care--a model supported by codes of ethics, the midwifery philosophy of care, and standards of practice.

Australian and U.S. news media portrayal of sharks and their conservation.

PubMed

Muter, Bret A; Gore, Meredith L; Gledhill, Katie S; Lamont, Christopher; Huveneers, Charlie

2013-02-01

Investigation of the social framing of human-shark interactions may provide useful strategies for integrating social, biological, and ecological knowledge into national and international policy discussions about shark conservation. One way to investigate social opinion and forces related to sharks and their conservation is through the media's coverage of sharks. We conducted a content analysis of 300 shark-related articles published in 20 major Australian and U.S. newspapers from 2000 to 2010. Shark attacks were the emphasis of over half the articles analyzed, and shark conservation was the primary topic of 11% of articles. Significantly more Australian articles than U.S. articles treated shark attacks (χ(2) = 3.862; Australian 58% vs. U.S. 47%) and shark conservation issues (χ(2) = 6.856; Australian 15% vs. U.S. 11%) as the primary article topic and used politicians as the primary risk messenger (i.e., primary person or authority sourced in the article) (χ(2) = 7.493; Australian 8% vs. U.S. 1%). However, significantly more U.S. articles than Australian articles discussed sharks as entertainment (e.g., subjects in movies, books, and television; χ(2) = 15.130; U.S. 6% vs. Australian 1%) and used scientists as the primary risk messenger (χ(2) = 5.333; U.S. 25% vs. Australian 15%). Despite evidence that many shark species are at risk of extinction, we found that most media coverage emphasized the risks sharks pose to people. To the extent that media reflects social opinion, our results highlight problems for shark conservation. We suggest that conservation professionals purposefully and frequently engage with the media to highlight the rarity of shark attacks, discuss preventative measures water users can take to reduce their vulnerability to shark encounters, and discuss conservation issues related to local and threatened species of sharks. When integrated with biological and ecological data, social-science data may help generate a more comprehensive perspective and inform conservation practice. © 2012 Society for Conservation Biology.

Research in Behavior Modification; New Developments and Implications.

ERIC Educational Resources Information Center

Krasner, Leonard, Ed.; Ullmann, Leonard P., Ed.

Fifteen articles by different authors discuss behavior modification in terms of research, training, and social application. Topics considered include the classification of behavioral pathology, the extension of learning principles to human behavior, studies of normal and deviant child behavior, operant conditioning of two speech-deficient boys,…

Educating Managers to Create Healthy Workplaces

ERIC Educational Resources Information Center

Gilbreath, Brad

2012-01-01

This article provides management educators with a comprehensive, research-based set of concepts they can use to enrich students' understanding of how to create healthy workplaces. To assist with that endeavor, learning objectives related to creating healthy workplaces are provided. Work environment stressors are discussed along with human and…

A Child's Brain: Part III.

ERIC Educational Resources Information Center

Sylwester, Robert

1982-01-01

This article, the last in a series about the human brain, focuses on the skin and its importance for the brain. Physiological functions of the skin, concerning touch and body protection, are explained, as well as its social role in nonverbal communication. Suggestions for student discussions are given. (PP)

Saving the Predators: Teaching About the Role of Predatory Animals.

ERIC Educational Resources Information Center

Soltow, Willow

1985-01-01

Discusses the role of predators in regulating prey populations, noting that this is an excellent example of the "interconnectedness" of life. Suggestions for films, books, articles, and student questions are given, and a special section dealing with human attitudes about predators is provided. (DH)

Who's Talking about Cake? A Reply to Weaver.

ERIC Educational Resources Information Center

Redmond, Mark V.; Waggoner, David W.

1992-01-01

Responds to a response to the authors' article on the development of a communication studies program at Iowa State University. Discusses some principles that might help others in reviewing their own departmental priorities and mission in developing a major that emphasizes the study of human communication. (RS)

Does Resistance Training Stimulate Cardiac Muscle Hypertrophy?

ERIC Educational Resources Information Center

Bloomer, Richard J.

2003-01-01

Reviews the literature on the left ventricular structural adaptations induced by resistance/strength exercise, focusing on human work, particularly well-trained strength athletes engaged in regular, moderate- to high-intensity resistance training (RT). The article discusses both genders and examines the use of anabolic-androgenic steroids in…

Careers in Health Services: A Guide to Major Health, Mental Health Professions

ERIC Educational Resources Information Center

Sanchez, Rodolfo B.

1977-01-01

The article discusses the diversity of jobs and challenges in human services, illustrates the opportunities available by citing examples of Hispanic workers and agencies active in the field, and provides a list of resources to help people explore the field further. (NQ)

Soft Skills at the Malaysian Institutes of Higher Learning

ERIC Educational Resources Information Center

Shakir, Roselina

2009-01-01

This article discusses human capital development through the seven soft skills elements which comprise communication skills, critical thinking and problem solving skills, team work, lifelong learning and information management skills, entrepreneurship skills, ethics, and professional moral and leadership skills. The Ministry of Higher Education,…

A Child's Brain. Part II. The Human Brain: How Every Single Cell is Organized for Action.

ERIC Educational Resources Information Center

Sylwester, Robert

1982-01-01

The second in a series of three articles concerning children's brain development focuses on the organization of the brain. Aspects of the brain's vertical, neocortex, and temporal organization are discussed and references for further reading are provided. (CJ)

The Classification of Substance Use Disorders: Historical, Contextual, and Conceptual Considerations

PubMed Central

Robinson, Sean M.; Adinoff, Bryon

2016-01-01

This article provides an overview of the history of substance use and misuse and chronicles the long shared history humans have had with psychoactive substances, including alcohol. The practical and personal functions of substances and the prevailing views of society towards substance users are described for selected historical periods and within certain cultural contexts. This article portrays how the changing historical and cultural milieu influences the prevailing medical, moral, and legal conceptualizations of substance use as reflected both in popular opinion and the consensus of the scientific community and represented by the American Psychiatric Association’s (APA) Diagnostic and Statistical Manual of Mental Disorders (DSM). Finally, this article discusses the efforts to classify substance use disorders (SUDs) and associated psychopathology in the APA compendium. Controversies both lingering and resolved in the field are discussed, and implications for the future of SUD diagnoses are identified. PMID:27548233

The Classification of Substance Use Disorders: Historical, Contextual, and Conceptual Considerations.

PubMed

Robinson, Sean M; Adinoff, Bryon

2016-08-18

This article provides an overview of the history of substance use and misuse and chronicles the long shared history humans have had with psychoactive substances, including alcohol. The practical and personal functions of substances and the prevailing views of society towards substance users are described for selected historical periods and within certain cultural contexts. This article portrays how the changing historical and cultural milieu influences the prevailing medical, moral, and legal conceptualizations of substance use as reflected both in popular opinion and the consensus of the scientific community and represented by the American Psychiatric Association's (APA) Diagnostic and Statistical Manual of Mental Disorders (DSM). Finally, this article discusses the efforts to classify substance use disorders (SUDs) and associated psychopathology in the APA compendium. Controversies both lingering and resolved in the field are discussed, and implications for the future of SUD diagnoses are identified.

Replication Proteins and Human Disease

PubMed Central

Jackson, Andrew P.; Laskey, Ronald A.; Coleman, Nicholas

2014-01-01

In this article, we discuss the significance of DNA replication proteins in human disease. There is a broad range of mutations in genes encoding replication proteins, which result in several distinct clinical disorders that share common themes. One group of replication proteins, the MCMs, has emerged as effective biomarkers for early detection of a range of common cancers. They offer practical and theoretical advantages over other replication proteins and have been developed for widespread clinical use. PMID:23881941

'Hurrah for the missing link!': a history of apes, ancestors and a crucial piece of evidence.

PubMed

Kjaergaard, Peter C

2011-03-20

In the nineteenth century the idea of a 'missing link' connecting humans with the rest of the animal kingdom was eagerly embraced by professional scientists and popularizers. After the publication of Charles Darwin's Origin of Species in 1859, many tied the idea and subsequent search for a crucial piece of evidence to Darwin and his formulation of the theory of evolution by natural selection. This article demonstrates that the expression was widely used and that the framework for discussions about human's relation to the apes and gaps in the fossil record were well in place and widely debated long before Origin of Species became the standard reference for discussing human evolution. In the second half of the century the missing link gradually became the ultimate prize in palaeoanthropology and grew into one of the most powerful, celebrated and criticized icons of human evolution.

Economic Holobiont: Influence of Parasites, Microbiota and Chemosignals on Economic Behavior

PubMed Central

Houdek, Petr

2018-01-01

The article is a perspective on utilization of microorganisms and chemosignals in studying human economic behavior. Research in biological roots of economic development has already confirmed that parasitic pressure influenced the creation and development of cultural norms and institutions. However, other effects of microorganisms on human groups and individual decision-making and behavior are heavily understudied. The perspective discusses how parasitic infections, sexually transmitted organisms and microbiota (i.e., “human holobiont”) could causally influence risk-seeking behavior, impulsivity, social dominance, empathy, political views and gender differences. As a case study, the parasite Toxoplasma gondii and its influence on economic preferences, personal characteristics and human appearance are examined. I also briefly review how chemosignals influence decision-making, particularly in the social preferences domain. I mention some predictions that arise from the paradigm of economic holobiont for the economic science. The conclusion summarizes limitations of the discussed findings and the stated speculations. PMID:29765310

Time for paradigmatic substitution in psychology. What are the alternatives?

PubMed

Kolstad, Arnulf

2010-03-01

This article focuses on the "machine paradigm" in psychology and its consequences for (mis)understanding of human beings. It discusses causes of the mainstream epistemology in Western societies, referring to philosophical traditions, the prestige of some natural sciences and mathematical statistics. It emphasizes how the higher psychological functions develop dialectically from a biological basis and how the brain due to its plasticity changes with mental and physical activity. This makes a causal machine paradigm unfit to describe and explain human psychology and human development. Some concepts for an alternative paradigm are suggested.

Dissecting the human immunologic memory for pathogens.

PubMed

Zielinski, Christina E; Corti, Davide; Mele, Federico; Pinto, Dora; Lanzavecchia, Antonio; Sallusto, Federica

2011-03-01

Studies on immunologic memory in animal models and especially in the human system are instrumental to identify mechanisms and correlates of protection necessary for vaccine development. In this article, we provide an overview of the cellular basis of immunologic memory. We also describe experimental approaches based on high throughput cell cultures, which we have developed to interrogate human memory T cells, B cells, and plasma cells. We discuss how these approaches can provide new tools and information for vaccine design, in a process that we define as 'analytic vaccinology'. © 2011 John Wiley & Sons A/S.

Urban bioclimatology.

PubMed

Mayer, H

1993-11-15

This article deals with the part of urban climatology which is of particular relevance to human beings. Presented first is a summary of all human biometerologically effective complexes, as well as other factors which are relevant to urban planning and which depend on atmospheric conditions in urban structures in a direct or indirect manner. Later, methods for human biometerologically significant assessment of thermal and air pollution components of the urban climate are discussed in detail, because these components can be strongly influenced by urban planning. The application of these methods is illustrated by some results of appropriate investigations in urban areas.

An overview of neural function and feedback control in human communication.

PubMed

Hood, L J

1998-01-01

The speech and hearing mechanisms depend on accurate sensory information and intact feedback mechanisms to facilitate communication. This article provides a brief overview of some components of the nervous system important for human communication and some electrophysiological methods used to measure cortical function in humans. An overview of automatic control and feedback mechanisms in general and as they pertain to the speech motor system and control of the hearing periphery is also presented, along with a discussion of how the speech and auditory systems interact.

The indicative analysis and ranking of human capital development

NASA Astrophysics Data System (ADS)

Inessa, Gurban; Alexandr, Tarasyev

2017-07-01

In this article we discuss the rationale for the importance and effectiveness of the regions ranking as a tool for regional social and economic policies aimed to control the regional socio-economic development. A methodological approach to the determination of the human capital development level in the regions of the Russian Federation is provided focused on determining the quality of human capital in each region of the Russian Federation and the causes underlying this situation. The methodological apparatus is based on the indicative qualimetric analysis method that allows to convert various benchmarks expressed in different units in a comparable type. Also it is possible to receive and differentiate a comprehensive assessment of the human capital level in each region of the Russian Federation on the basis of the proposed classification. In this article we present the structure of the indicators system that simulates the human capital level by a number of descriptive components including demographic, educational, employment, research and socio-cultural components. In our research we found that in the overwhelming majority of the Russian Federation human capital is characterized mainly by a low development level. The system shows unstable dynamics in the human capital level through the Russian Federal Districts, as well as the leaders and laggards in the rating of the Russian Federation during the period 2000-2013. Our article presents the structure of a comprehensive assessment of the human capital level by providing estimates of its components.

Indicators of ocean health and human health: developing a research and monitoring framework.

PubMed Central

Knap, Anthony; Dewailly, Eric; Furgal, Chris; Galvin, Jennifer; Baden, Dan; Bowen, Robert E; Depledge, Michael; Duguay, Linda; Fleming, Lora E; Ford, Tim; Moser, Fredricka; Owen, Richard; Suk, William A; Unluata, Umit

2002-01-01

We need to critically assess the present quality of the marine ecosystem, especially the connection between ecosystem change and threats to human health. In this article we review the current state of indicators to link changes in marine organisms with eventual effects to human health, identify research opportunities in the use of indicators of ocean and human health, and discuss how to establish collaborations between national and international governmental and private sector groups. We present a synthesis of the present state of understanding of the connection between ocean health and human health, a discussion of areas where resources are required, and a discussion of critical research needs and a template for future work in this field. To understand fully the interactions between ocean health and human health, programs should be organized around a "models-based" approach focusing on critical themes and attributes of marine environmental and public health risks. Given the extent and complex nature of ocean and human health issues, a program networking across geographic and disciplinary boundaries is essential. The overall goal of this approach would be the early detection of potential marine-based contaminants, the protection of marine ecosystems, the prevention of associated human illness, and by implication, the development of products to enhance human well-being. The tight connection between research and monitoring is essential to develop such an indicator-based effort. PMID:12204815

Human rights responsibilities of pharmaceutical companies in relation to access to medicines.

PubMed

Lee, Joo-Young; Hunt, Paul

2012-01-01

Although access to medicines is a vital feature of the right to the highest attainable standard of health ("right to health"), almost two billion people lack access to essential medicines, leading to immense avoidable suffering. While the human rights responsibility to provide access to medicines lies mainly with States, pharmaceutical companies also have human rights responsibilities in relation to access to medicines. This article provides an introduction to these responsibilities. It briefly outlines the new UN Guiding Principles on Business and Human Rights and places the human rights responsibilities of pharmaceutical companies in this context. The authors draw from the work of the first UN Special Rapporteur on the right to the highest attainable standard of health, in particular the Human Rights Guidelines for Pharmaceutical Companies in Relation to Access to Medicines that he presented to the UN General Assembly in 2008, and his UN report on GlaxoSmithKline (GSK). While the Guiding Principles on Business and Human Rights are general human rights standards applicable to all business entities, the Human Rights Guidelines for Pharmaceutical Companies consider the specific human rights responsibilities of one sector (pharmaceutical companies) in relation to one area of activity (access to medicines). The article signals the human rights responsibilities of all pharmaceutical companies, with particular attention to patent-holding pharmaceutical companies. Adopting a right-to-health "lens," the article discusses GSK and accountability. The authors argue that human rights should shape pharmaceutical companies' policies, and provide standards in relation to which pharmaceutical companies could, and should, be held accountable. They conclude that it is now crucial to devise independent, accessible, transparent, and effective mechanisms to monitor pharmaceutical companies and hold them publicly accountable for their human rights responsibilities. © 2012 American Society of Law, Medicine & Ethics, Inc.

Learning about Children Learning about Squirrels

ERIC Educational Resources Information Center

Diamond, Julie

2007-01-01

This article describes a curriculum developed by the author and the children in her public school kindergarten class. Teaching practices that foster children's intellectual--and overall human--development are documented. The goals and purposes of schooling are discussed as well as issues pertaining to the role of the teacher, structures that…

Education for Sustainable Human Development: Towards a Definition

ERIC Educational Resources Information Center

Landorf, Hilary; Doscher, Stephanie; Rocco, Tonette

2008-01-01

Three years into the Decade of Education for Sustainable Development, there has been considerable discussion regarding education for sustainable development (ESD) at a policy level, yet very few countries and communities have moved to integrate ESD into their educational curriculum. In this article we argue that the conceptualization and…

Musical Parenting and Music Education: Integrating Research and Practice

ERIC Educational Resources Information Center

Ilari, Beatriz

2018-01-01

Although teachers work constantly with parents, discussions concerning parental roles in children's music learning are often left at the margins in music teacher training programs. The aim of this article is to offer a review of musical parenting research from an ecological perspective. Bronfenbrenner's bioecological theory of human development is…

Humans, Sharks and the Shared Environment in the Contemporary Eco-Doc

ERIC Educational Resources Information Center

Hughes, Helen

2011-01-01

Focussing on the film "Sharkwater" directed by Rob Stewart (2006), this article discusses formal interpretive aspects of recent environmental documentaries which are intended to raise awareness about environmental issues. It is argued that contemporary environmental documentaries seek to persuade audiences to protect the shared physical…

Use of Audiovisual Texts in University Education Process

ERIC Educational Resources Information Center

Aleksandrov, Evgeniy P.

2014-01-01

Audio-visual learning technologies offer great opportunities in the development of students' analytical and projective abilities. These technologies can be used in classroom activities and for homework. This article discusses the features of audiovisual media texts use in a series of social sciences and humanities in the University curriculum.

Battling for Hearts and Minds

ERIC Educational Resources Information Center

Bousquet, Marc

2008-01-01

In this article, the author discusses how the new trends in corporate management are changing the ways in which the administration deals with faculty culture. Informed by trends in corporate management, administration is turning away from the human-resources model of developing individual potential and is taking as its goal instead the…

Improving Student Naval Aviator Aircraft Carrier Landing Performance

ERIC Educational Resources Information Center

Sheppard, Thomas H.; Foster, T. Chris

2008-01-01

This article discusses the use of human performance technology (HPT) to improve qualification rates for learning to land onboard aircraft carriers. This project started as a request for a business case analysis and evolved into a full-fledged performance improvement project, from mission analysis through evaluation. The result was a significant…

Our Brains Extended

ERIC Educational Resources Information Center

Prensky, Marc

2013-01-01

Technology is an extension of the brain; it is a new way of thinking. It is the solution humans have created to deal with the difficult new context of variability, uncertainty, complexity, and ambiguity. Wise integration of evolving and powerful technology demands a rethinking of the curriculum. This article discusses technology as the new way of…

A New Bloom: Transforming Learning

ERIC Educational Resources Information Center

Cochran, David; Conklin, Jack

2007-01-01

This article discusses a new design for the classic Bloom's Taxonomy developed by Anderson, L. W. & Krathwohl, D. (2001), which can be used to evaluate learners' technology-enhanced experience in more powerful and critical ways. The New Bloom's Taxonomy incorporates contemporary research on learning and human cognition into its model. The…

Assessing Individual Support Needs to Enhance Personal Outcomes

ERIC Educational Resources Information Center

van Loon, Jos; Claes, Claudia; Vandevelde, Stijn; Van Hove, Geert; Schalock, Robert L.

2010-01-01

Education and human service organizations providing services to people with intellectual and closely related developmental disabilities are increasingly being impacted by the supports paradigm, the quality of life concept, and the evaluation of personal outcomes. In this article the authors discuss the relationship among these three areas,…

Man and the Environment: The Need for a More Realistic Approach to Teaching Ecology.

ERIC Educational Resources Information Center

Evans, Stewart M.

1988-01-01

This article argues that Biology syllabi give insufficient attention to the role humans play in the ecological processes and interactions with their environment. Discussed are ecological studies in urban and managed habitats, using a multidisciplinary approach, and including a global perspective. (CW)

Theme--Achieving 2020. Goal 3: All Students Are Conversationally Literate in Agriculture, Food, Fiber, and Natural Resource Systems.

ERIC Educational Resources Information Center

Trexler, Cary, Ed.

2000-01-01

Nine theme articles focus on the need for students to be conversationally literate about agriculture, food, fiber, and natural resources systems. Discusses the definition of conversational literacy, the human and institutional resources needed, and exemplary models for promoting literacy. (JOW)

Fungi as a Source of Food.

PubMed

Dupont, Joëlle; Dequin, Sylvie; Giraud, Tatiana; Le Tacon, François; Marsit, Souhir; Ropars, Jeanne; Richard, Franck; Selosse, Marc-André

2017-06-01

In this article, we review some of the best-studied fungi used as food sources, in particular, the cheese fungi, the truffles, and the fungi used for drink fermentation such as beer, wine, and sake. We discuss their history of consumption by humans and the genomic mechanisms of adaptation during artificial selection.

People and Technology Today: Some Educational Implications

ERIC Educational Resources Information Center

Rodriguez-Sedano, Alfredo; Paris, Ana Costa; Mut, Maite Dassoy

2011-01-01

The present article approaches some of the educational implications borne by humanity with technological progress. We begin by pointing out significant data that classify what is considered relevant. Then, confronting the future is discussed by analyzing the attitudes necessary to promote the goals. Confronted with these challenges, three possible…

Speaking Personally--With Chere Campbell Gibson

ERIC Educational Resources Information Center

Olgren, Christine

2008-01-01

This article presents an interview with Chere Campbell Gibson, a professor emerita in the School of Human Ecology and graduate program in Continuing and Vocational Education at the University of Wisconsin-Madison. Gibson shares her years of experience in distance education, discusses her book titled "Distance Learners in Higher Education:…

Regulations: Can They Control Staff Compliance in Human Services Systems?

ERIC Educational Resources Information Center

Jacobson, John W.

1990-01-01

This article discusses results of regulations for Intermediate Care Facilities for the Mentally Retarded, arguing that, by establishing minimum standards for funding, these policies promote mediocrity. Strategies for promoting compliance behaviors are offered, as are observations on regulatory reform and the process of regulatory impact. (PB)

Relevance Theory, Action Theory and Second Language Communication Strategies

ERIC Educational Resources Information Center

Foster-Cohen, Susan H.

2004-01-01

The discussion in this article offers a comparison between Relevance Theory as an account of human communication and Herbert Clark's (1996) sociocognitive Action Theory approach. It is argued that the differences are fundamental and impact analysis of all kinds of naturally occurring communicative data, including that produced by non-native…

Didactics: From Classical Rhetoric to Kitchen-Latin

ERIC Educational Resources Information Center

Nordkvelle, Yngve Troye

2003-01-01

The article discusses the relationship between the ancient traditions of dialectics and rhetoric and the transformations they underwent through the Middle Ages and the Renaissance, particularly because of the emergence of Humanism. The French philosopher Pierre de la Ramee (1515-1572) played an essential role in this transformation. The logic…

Understanding the Etiology of Complex Traits: Symbiotic Relationships between Psychology and Genetics

ERIC Educational Resources Information Center

Grigorenko, Elena L.

2007-01-01

The present article offers comments on the infusion of methodologies, approaches, reasoning strategies, and findings from the fields of genetics and genomics into studies of complex human behaviors (hereafter, complex phenotypes). Specifically, I discuss issues of generality and specificity, causality, and replicability as they pertain to…

Depicting the Suffering of Others

ERIC Educational Resources Information Center

Kostouros, Patricia

2016-01-01

This article offers a discussion about the depiction of traumatic materials to postsecondary human service students. Presently there is an on-going debate about trigger warnings and whether trigger warnings are necessary prior to engaging in materials that depict the suffering of others. Perhaps after depicting graphic images some teachers have…

Movement.

ERIC Educational Resources Information Center

Roberts, Lynda S.

This document summarizes 20 articles and books which stress the importance of movement in the overall development of the human species. Each summary ranges in length from 100 to 200 words and often includes direct quotations. A wide range of movement activities suitable for people of all ages (from infants to adults) are discussed. Many summaries…

Performing Witnessing: Dramatic Engagement, Trauma and Museum Installations

ERIC Educational Resources Information Center

Hughes, Erika

2018-01-01

This article offers a discussion of two interactive museum installations, 'Remembering the Children: Daniel's Story' at the United States Holocaust Memorial Museum in Washington, DC, and the main exhibit at the Humanity House Museum in the Hague, Netherlands. Both are examples of what I term "self-guided dramas," taking the…

Understanding How Babies Build Language Skills

ERIC Educational Resources Information Center

Honig, Alice Sterling

2006-01-01

Language is a great communication system. Through language, humans can express logical reasoning, grief, happiness, wishes, descriptions, and a rich array of feelings and ideas. Every baby deserves the gift of language power! In this article, the author discusses how babies build language skills and presents activities to help babies build…

Teaching the Social Issues of a Sustainable Food Supply

ERIC Educational Resources Information Center

Shuttleworth, Jay

2015-01-01

Understanding the pressing need for humans to limit their consumption to more supportable levels, this study investigated how one social studies teacher taught the social issues associated with a sustainable food supply. This article discusses what the teacher's curricular, pedagogical, and assessment strategies were in engaging students with…

Romanian Higher Education as a Facilitator of Romania's Continued Formal and Informal Integration in the European Union

ERIC Educational Resources Information Center

Salajan, Florin D.; Chiper, Sorina

2013-01-01

This article conducts an exploration of Romania's European integration process through higher education. It contends that integration occurs at "formal" and "informal levels" through institutional norms and human agency, respectively. Through theoretical and empirical analysis, the authors discuss the modalities through which…

On Evaluating Human Problem Solving of Computationally Hard Problems

ERIC Educational Resources Information Center

Carruthers, Sarah; Stege, Ulrike

2013-01-01

This article is concerned with how computer science, and more exactly computational complexity theory, can inform cognitive science. In particular, we suggest factors to be taken into account when investigating how people deal with computational hardness. This discussion will address the two upper levels of Marr's Level Theory: the computational…

Traditional Use and Avoidance of Foods of Animal Origin: A Culture Historical View

ERIC Educational Resources Information Center

Simoons, Frederick J.

1978-01-01

This article discusses pork avoidance in the Near East, the sacred cow concept of Hinduism, the use of horsemeat in Western Europe, the rejection of fish as human food in Africa and Asia, and the use of milk and dairy products. (Author/BB)

Integrating cultural resources and wilderness character

Treesearch

Jill Cowley; Peter Landres; Melissa Memory; Doug Scott; Adrienne Lindholm

2012-01-01

Cultural resources are an integral part of wilderness and wilderness character, and all wilderness areas have a human history. This article develops a foundation for wilderness and cultural resource staffs to continue communicating with one another in order to make better decisions for wilderness stewardship. Following a discussion of relevant legislative history, we...

How Boys Learn

ERIC Educational Resources Information Center

Gurian, Michael; Stevens, Kathy

2006-01-01

In this article, the authors talk about the state of boyhood in education and explain the idea that not all elements of the brain--especially not gender--are plastic. They discuss the mismatch between boys and conventional education and how gender "really" happens in the brain and describe the three biological stages in which human nature…

Prologue: Developing Evidence-based Practices and Research Collaborations in School Settings.

ERIC Educational Resources Information Center

Apel, Kenn

2001-01-01

This introductory article discusses factors that have led to changes in speech-language pathology practices, including a better and broader understanding of the human communication process, revised federal guidelines and regulations for special education and related services, and a strong desire to encourage scientific pursuit through…

Controlling Population with Pollution

ERIC Educational Resources Information Center

Browne, Joseph

2010-01-01

Population models are often discussed in algebra, calculus, and differential equations courses. In this article we will use the human population of the world as our application. After quick looks at two common models we'll investigate more deeply a model which incorporates the negative effect that accumulated pollution may have on population.

Media Literacy through Photography and Participation. A Conceptual Approach

ERIC Educational Resources Information Center

Rabadán, Ángel V.

2015-01-01

We are living in social massification processes that oppress our identity and specificity as a human group; however, there are tools increasingly present among researchers, educators and other professionals who help to develop interpretations and create knowledge by developing a participatory communication perspective. This article discusses how…

Commonalities between Disaster and Climate Change Risks for Health: A Theoretical Framework.

PubMed

Banwell, Nicola; Rutherford, Shannon; Mackey, Brendan; Street, Roger; Chu, Cordia

2018-03-16

Disasters and climate change have significant implications for human health worldwide. Both climate change and the climate-sensitive hazards that result in disasters, are discussed in terms of direct and indirect impacts on health. A growing body of literature has argued for the need to link disaster risk reduction and climate change adaptation. However, there is limited articulation of the commonalities between these health impacts. Understanding the shared risk pathways is an important starting point for developing joint strategies for adapting to, and reducing, health risks. Therefore, this article discusses the common aspects of direct and indirect health risks of climate change and climate-sensitive disasters. Based on this discussion a theoretical framework is presented for understanding these commonalities. As such, this article hopes to extend the current health impact frameworks and provide a platform for further research exploring opportunities for linked adaptation and risk reduction strategies.

Commonalities between Disaster and Climate Change Risks for Health: A Theoretical Framework

PubMed Central

Banwell, Nicola; Rutherford, Shannon; Mackey, Brendan; Street, Roger; Chu, Cordia

2018-01-01

Disasters and climate change have significant implications for human health worldwide. Both climate change and the climate-sensitive hazards that result in disasters, are discussed in terms of direct and indirect impacts on health. A growing body of literature has argued for the need to link disaster risk reduction and climate change adaptation. However, there is limited articulation of the commonalities between these health impacts. Understanding the shared risk pathways is an important starting point for developing joint strategies for adapting to, and reducing, health risks. Therefore, this article discusses the common aspects of direct and indirect health risks of climate change and climate-sensitive disasters. Based on this discussion a theoretical framework is presented for understanding these commonalities. As such, this article hopes to extend the current health impact frameworks and provide a platform for further research exploring opportunities for linked adaptation and risk reduction strategies. PMID:29547592

Access to health care as a human right in international policy: critical reflections and contemporary challenges.

PubMed

Castillo, Camilo Hernán Manchola; Garrafa, Volnei; Cunha, Thiago; Hellmann, Fernando

2017-07-01

Using the United Nations (UN) and its subordinate body, the World Health Organization (WHO), as a frame of reference, this article explores access to healthcare as a human right in international intergovernmental policies. First, we look at how the theme of health is treated within the UN, focusing on the concept of global health. We then discuss the concept of global health from a human rights perspective and go on to outline the debate surrounding universal coverage versus universal access as a human right, addressing some important ethical questions. Thereafter, we discuss universal coverage versus universal access using the critical and constructivist theories of international relations as a frame of reference. Finally, it is concluded that, faced with the persistence of huge global health inequalities, the WHO began to reshape itself, leaving behind the notion of health as a human right and imposing the challenge of reducing the wide gap that separates international intergovernmental laws from reality.

GRAPES-Grounding representations in action, perception, and emotion systems: How object properties and categories are represented in the human brain.

PubMed

Martin, Alex

2016-08-01

In this article, I discuss some of the latest functional neuroimaging findings on the organization of object concepts in the human brain. I argue that these data provide strong support for viewing concepts as the products of highly interactive neural circuits grounded in the action, perception, and emotion systems. The nodes of these circuits are defined by regions representing specific object properties (e.g., form, color, and motion) and thus are property-specific, rather than strictly modality-specific. How these circuits are modified by external and internal environmental demands, the distinction between representational content and format, and the grounding of abstract social concepts are also discussed.

Is Human-induced Pluripotent Stem Cell the Best Optimal?

PubMed

Wang, Feng; Kong, Jie; Cui, Yi-Yao; Liu, Peng; Wen, Jian-Yan

2018-04-05

Since the advent of induced pluripotent stem cell (iPSC) technology a decade ago, enormous progress has been made in stem cell biology and regenerative medicine. Human iPSCs have been widely used for disease modeling, drug discovery, and cell therapy development. In this review, we discuss the progress in applications of iPSC technology that are particularly relevant to drug discovery and regenerative medicine, and consider the remaining challenges and the emerging opportunities in the field. Articles in this review were searched from PubMed database from January 2014 to December 2017. Original articles about iPSCs and cardiovascular diseases were included and analyzed. iPSC holds great promises for human disease modeling, drug discovery, and stem cell-based therapy, and this potential is only beginning to be realized. However, several important issues remain to be addressed. The recent availability of human cardiomyocytes derived from iPSCs opens new opportunities to build in vitro models of cardiac disease, screening for new drugs and patient-specific cardiac therapy.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shalat, S.L.; Walker, D.B.; Finnell, R.H.

Arsenic has been recognized as a human toxicant for over 2000 years. More recently it has been readily accepted as a human carcinogen. Animal research has demonstrated arsenic`s ability to have profound detrimental effects on the developing embryo in avian and mamalian species. This article comprehensively reviews the human and animal literature on the subject of the reproductive toxicity of arsenic. A variety of endpoints are considered, including spontaneous abortion, cardiovascular defects, and arsenic`s role in the causation of neural tube defects (NTDs). A summary of the literature that has examined the various postulated mechanisms by which arsenic may producemore » NTDs is also considered. In addition, a discussion of literature relative to the presence of arsenic in the general environment and in the workplace presented. This article reaches the conclusion that while further research is clearly needed, particularly on the potential toxicity of organic arsenical compounds, the current literature suggests it may be prudent and appropriate to treat inorganic arsenic as a probable human reproductive toxin. 132 refs.« less

Emerging infectious diseases at the beginning of the 21st century.

PubMed

Lashley, Felissa R

2006-01-31

The emergence and re-emergence of infectious diseases involves many interrelated factors. Global interconnectedness continues to increase with international travel and trade; economic, political, and cultural interactions; and human-to-human and animal-to-human interactions. These interactions include the accidental and deliberate sharing of microbial agents and antimicrobial resistance and allow the emergence of new and unrecognized microbial disease agents. As the 21st century begins, already new agents have been identified, and new outbreaks have occurred. Solutions to limiting the spread of emerging infectious diseases will require cooperative efforts among many disciplines and entities worldwide. This article defines emerging infectious diseases, summarizes historical background, and discusses factors that contribute to emergence. Seven agents that have made a significant appearance, particularly in the 21st century, are reviewed, including: Ebola and Marburg hemorrhagic fevers, human monkeypox, bovine spongiform encephalopathy, severe acute respiratory syndrome (SARS), West Nile virus, and avian influenza. The article provides for each agent a brief historical background, case descriptions, and health care implications.

[Projective identification in human relations].

PubMed

Göka, Erol; Yüksel, Fatih Volkan; Göral, F Sevinç

2006-01-01

Melanie Klein, one of the pioneers of Object Relations Theory, first defined "projective identification", which is regarded as one of the most efficacious psychoanalytic concepts after the discovery of the "unconscious". Examination of the literature on "projective identification" shows that there are various perspectives and theories suggesting different uses of this concept. Some clinicians argue that projective identification is a primitive defense mechanism observed in severe psychopathologies like psychotic disorder and borderline personality disorder, where the intra-psychic structure has been damaged severely. Others suggest it to be an indispensable part of the transference and counter-transference between the therapist and the patient during psychotherapy and it can be used as a treatment material in the therapy by a skillful therapist. The latter group expands the use of the concept through normal daily relationships by stating that projective identification is one type of communication and part of the main human relation mechanism operating in all close relationships. Therefore, they suggest that projective identification has benign forms experienced in human relations as well as malign forms seen in psychopathologies. Thus, discussions about the definition of the concept appear complex. In order to clarify and overcome the complexity of the concept, Melanie Klein's and other most important subsequent approaches are discussed in this review article. Thereby, the article aims to explain its important function in understanding the psychopathologies, psychotherapeutic relationships and different areas of normal human relations.

Managing Boundaries: The Role of Non-Profit Organisations in Russia’s Managed Democracy

PubMed Central

Ljubownikow, Sergej; Crotty, Jo

2017-01-01

This article examines Russian human service non-profit organisations (NPOs) to investigate the nature of civil society in a managed democracy. Specifically the focus is on emerging vertical ties between NPOs and ruling and governing elites. Drawing on qualitative data collected from health and education NPOs in three industrial regions, we find that in establishing such vertical ties the role of organisations and individuals within is changing – they have moved away from ignored outsiders towards accessing the circles of power and being tasked with managing the boundary between the state and civil society. In exploring these arrangements this article highlights that in the post-Soviet space, NPOs and the state are closely intertwined resembling co-optation. As a result the democratisation potential of human service NPOs is constrained. In discussing these insights we also draw parallels to contexts in which the state has outsourced welfare service to human service NPOs. PMID:28989196

Patents and the obligation to protect health: examining the significance of human rights considerations in the protection of pharmaceutical patents.

PubMed

Owoeye, Olasupo Ayodeji

2014-06-01

This article discusses the human right to health in the context of patent protection and access to medicines. It considers the limitations in international human rights law, especially in relation to socioeconomic rights, that make it difficult for the right to health to be a potent justification for derogation from trade or intellectual property agreements. It concludes by taking the view that while the right to health may be somewhat unenforceable in international law, its close association with enforceable rights such as the right to life can be a legitimate basis for making maximum use of the flexibilities in the international intellectual property regime to protect public health. The article takes the view that trade and intellectual property agreements must be interpreted in a way that endeavours as much as possible to resolve any seeming inconsistency with the right to health.

Value for money in South African health care: findings of a review of health expenditure and finance.

PubMed

Doherty, J; McIntyre, D; Bloom, G

1996-01-01

This article highlights the most striking findings of a review of health expenditure and finance in South Africa in 1992/3. The level of national expenditure on health care, and the distribution of resources between the public and private sectors, are discussed first. Then the article highlights the maldistribution of financial, physical and human resources on a geographic basis, racially and between levels of care. The cost of redressing inequities, at least at the primary care level, is mentioned in the context of seeking options for additional sources of finance. The article concludes by examining the planning prerequisites for successful reform.

Review of research and developments in self healing composite materials

NASA Astrophysics Data System (ADS)

Reddy Madara, Sahith; Sarath Raj, N. S.; Pon Selvan, Chithirai, Dr.

2018-04-01

Self-healing materials are artificial or synthetically created substances that have the built-in ability to automatically repair damage to themselves without any external diagnosis of the problem or human intervention. This article presents the current research and developments in self-healing composite materials. A detailed study is conducted on various types of self-healing composites with their self-healing mechanisms. The applications of self-healing materials in various fields including space sector is also discussed. Economics and Future outlooks for self-healing smart materials is highlighted at the end of the article. This research article will be useful to manufacturers, policy makers and researchers widely.

Heart regeneration.

PubMed

Breckwoldt, Kaja; Weinberger, Florian; Eschenhagen, Thomas

2016-07-01

Regenerating an injured heart holds great promise for millions of patients suffering from heart diseases. Since the human heart has very limited regenerative capacity, this is a challenging task. Numerous strategies aiming to improve heart function have been developed. In this review we focus on approaches intending to replace damaged heart muscle by new cardiomyocytes. Different strategies for the production of cardiomyocytes from human embryonic stem cells or human induced pluripotent stem cells, by direct reprogramming and induction of cardiomyocyte proliferation are discussed regarding their therapeutic potential and respective advantages and disadvantages. Furthermore, different methods for the transplantation of pluripotent stem cell-derived cardiomyocytes are described and their clinical perspectives are discussed. This article is part of a Special Issue entitled: Cardiomyocyte Biology: Integration of Developmental and Environmental Cues in the Heart edited by Marcus Schaub and Hughes Abriel. Copyright © 2015 Elsevier B.V. All rights reserved.

The role of international institutions in the formation of international bioethical law: UNESCO and the United Nations General Assembly attempt to govern human cloning.

PubMed

Kuppuswamy, Chamundeeswari

2007-01-01

This article analyses the international governance of human reproductive cloning. Noting that bioethics is a new field of engagement for international lawyers, it recounts some of the institutional developments in bioethical law making. The role of UNESCO and the United Nations General Assembly is scrutinized and the author discusses the relative merits of the institutions' governance of human reproductive cloning. The author suggests that some international institutions and mechanisms are better suited than others for bioethical law making. The 2005 General Assembly resolution on human cloning is analysed in this context.

Why do viruses cause cancer? Highlights of the first century of human tumour virology

PubMed Central

Moore, Patrick S.; Chang, Yuan

2013-01-01

The year 2011 marks the centenary of Francis Peyton Rous’s landmark experiments on an avian cancer virus. Since then, seven human viruses have been found to cause 10–15% of human cancers worldwide. Viruses have been central to modern cancer research and provide profound insights into both infectious and non-infectious cancer causes. This diverse group of viruses reveals unexpected connections between innate immunity, immune sensors and tumour suppressor signalling that control both viral infection and cancer. This Timeline article describes common features of human tumour viruses and discusses how new technologies can be used to identify infectious causes of cancer. PMID:21102637

She's not a person...she's just a woman! Infra-humanization and intimate partner violence.

PubMed

Baldry, Anna Costanza; Pacilli, Maria Giuseppina; Pagliaro, Stefano

2015-05-01

This article examines the association between a target's perceived humanness and individuals' willingness to provide help and support in cases of violence against women (VAW), specifically, intimate partner violence (IPV). In an experimental study, undergraduates read a fictitious article from a newspaper describing an IPV episode of a man hitting his wife and accusing her of cheating on him. According to the experimental condition, they then read that the victim either had or had not admitted the infidelity. Participants then judged the victim on an infra-humanization scale and expressed their willingness to provide help and support to the victim herself as if they were a neighbor witnessing the attack. Results showed that a victim admitting an affair with another man (admission condition) elicited lower perceived humanness and lower willingness to provide help than a victim denying such adultery (no admission condition). Moreover, targets' perceived humanness mediated the effect of contextual features on participants' willingness to provide help to the victim. Results are discussed in terms of victim blaming, and practical implications for prevention strategies are presented. © The Author(s) 2014.

Climate Change, Climate Justice, and Environmental Health: Implications for the Nursing Profession.

PubMed

Nicholas, Patrice K; Breakey, Suellen

2017-11-01

Climate change is an emerging challenge linked to negative outcomes for the environment and human health. Since the 1960s, there has been a growing recognition of the need to address climate change and the impact of greenhouse gas emissions implicated in the warming of our planet. There are also deleterious health outcomes linked to complex climate changes that are emerging in the 21st century. This article addresses the social justice issues associated with climate change and human health and discussion of climate justice. Discussion paper. A literature search of electronic databases was conducted for articles, texts, and documents related to climate change, climate justice, and human health. The literature suggests that those who contribute least to global warming are those who will disproportionately be affected by the negative health outcomes of climate change. The concept of climate justice and the role of the Mary Robinson Foundation-Climate Justice are discussed within a framework of nursing's professional responsibility and the importance of social justice for the world's people. The nursing profession must take a leadership role in engaging in policy and advocacy discussions in addressing the looming problems associated with climate change. Nursing organizations have adopted resolutions and engaged in leadership roles to address climate change at the local, regional, national, and global level. It is essential that nurses embrace concepts related to social justice and engage in the policy debate regarding the deleterious effects on human health related to global warming and climate change. Nursing's commitment to social justice offers an opportunity to offer significant global leadership in addressing the health implications related to climate change. Recognizing the negative impacts of climate change on well-being and the underlying socioeconomic reasons for their disproportionate and inequitable distribution can expand and optimize the profession's role in education, practice, research, and policy-making efforts to address climate change. © 2017 Sigma Theta Tau International.

Domestic minor sex trafficking: what the PNP needs to know.

PubMed

Hornor, Gail

2015-01-01

Human trafficking is a major global public health problem and represents a substantial human rights violation. Human trafficking has been receiving attention in both the lay media and professional literature. Human trafficking can include commercial sex, forced labor, child soldiers, and stealing of human organs. One form of human trafficking represents a significant American pediatric health problem: domestic minor sex trafficking (DMST). DMST is the commercial sexual abuse of children by selling, buying, or trading their sexual service. This continuing education article will define DMST and discuss it in terms of prevalence, risk factors, and practice implications for the pediatric nurse practitioner. Copyright © 2015 National Association of Pediatric Nurse Practitioners. Published by Elsevier Inc. All rights reserved.

Towards a CRISPR view of early human development: applications, limitations and ethical concerns of genome editing in human embryos.

PubMed

Plaza Reyes, Alvaro; Lanner, Fredrik

2017-01-01

Developmental biologists have become increasingly aware that the wealth of knowledge generated through genetic studies of pre-implantation mouse development might not easily be translated to the human embryo. Comparative studies have been fueled by recent technological advances in single-cell analysis, allowing in-depth analysis of the human embryo. This field could shortly gain more momentum as novel genome editing technologies might, for the first time, also allow functional genetic studies in the human embryo. In this Spotlight article, we summarize the CRISPR-Cas9 genome editing system and discuss its potential applications and limitations in human pre-implantation embryos, and the ethical considerations thereof. © 2017. Published by The Company of Biologists Ltd.

Revisiting Vygotsky and Gardner: Realizing Human Potential

ERIC Educational Resources Information Center

Beliavsky, Ninah

2006-01-01

In this article, the author discusses her views on philosophies and theories by Lev Semenovich Vygotsky and Howard Gardner. Here, she argues that Vygotsky's ideas should be viewed through the prism of Gardner's theory of Multiple Intelligences, and that the combination of these concepts can shed new light on education--on teaching and learning.…

The Role of Radical Imagination in Social Work Education, Practice, and Research

ERIC Educational Resources Information Center

Barnetz, Zion

2015-01-01

This article addresses the role of imagination in social work education, practice, and research. Following a brief discussion of terms, the author attempts to identify the various contributions of human imagination to social change processes. The second part presents the argument that the cultural structure known as Social Darwinism significantly…

Examining Values, Use, and Role in Evaluation: Prospects for a Broadened View

ERIC Educational Resources Information Center

Boulay, David A.; Han, Heeyoung

2008-01-01

This article reviews evaluation studies published in the HRD (human resource development) field. The authors further discuss general evaluation theories in terms of value, use, and evaluator role. The comparison of this literature suggests that evaluation in HRD has been limited by narrow perspectives. The authors attribute this narrow notion of…

Revisiting the "Trans-Human" Gestalt: Discussing "Nature" and "Development" with Students of Sustainable Business

ERIC Educational Resources Information Center

Kopnina, Helen

2014-01-01

This article explores the perceptions of development through metaphor use by students of International Business Management Studies at The Hague University. Students' reflections upon the concepts of nature and development before and after educational intervention are examined through discourse analysis and narrative analysis. Results show that…

Twitter for Libraries (and Librarians)

ERIC Educational Resources Information Center

Milstein, Sarah

2009-01-01

For many people, the word "twitter" brings to mind birds rather than humans. But information professionals know that Twitter (www.twitter.com) is a fast-growing, free messaging service for people, and it's one that libraries (and librarians) can make good use of--without spending much time or effort. This article discusses the many potential uses…

From Embodiment to Emplacement: Re-Thinking Competing Bodies, Senses and Spatialities

ERIC Educational Resources Information Center

Pink, Sarah

2011-01-01

In this article I discuss how a shift from theories of embodiment to one of emplacement can inform how we understand the performing body in competitive and pedagogical contexts. I argue that recent theoretical advances concerning the senses, human perception and place offer new analytical possibilities for understanding skilled performances and…

Taking the Fear out of Suicide Assessment and Intervention: A Pedagogical and Humanistic Practice

ERIC Educational Resources Information Center

Miller, Lynne Guillot; McGlothlin, Jason M.; West, John D.

2013-01-01

This article provides ideas for teaching suicide assessment and intervention according to differing student learning styles and preferences. The authors discuss how considering the learning styles and uniqueness of counselors-in-training while assessing the complexity of suicidality can contribute to the literature on humanism and lead to more…

The Most Important of All the Organs: Darwin on the Brain

ERIC Educational Resources Information Center

Jacyna, Stephen

2009-01-01

This article discusses Charles Darwin's interest in topics that may broadly be defined as "neurological" in character. Using published and manuscript materials, it examines the sources of Darwin's knowledge of neurological matters and seeks to explain why questions concerning the relation of mind and brain both in humans and other animals were…

Human Performance on Insight Problem Solving: A Review

ERIC Educational Resources Information Center

Chu, Yun; MacGregor, James N.

2011-01-01

The article provides a review of recent research on insight problem-solving performance. We discuss what insight problems are, the different types of classic and newer insight problems, and how we can classify them. We also explain some of the other aspects that affect insight performance, such as hints, analogs, training, thinking aloud, and…

01010000 01001100 01000001 01011001: Play Elements in Computer Programming

ERIC Educational Resources Information Center

Breslin, Samantha

2013-01-01

This article explores the role of play in human interaction with computers in the context of computer programming. The author considers many facets of programming including the literary practice of coding, the abstract design of programs, and more mundane activities such as testing, debugging, and hacking. She discusses how these incorporate the…

Interdisciplinary Intellect: HASTAC and the Commitment to Encourage Collective Intelligence

ERIC Educational Resources Information Center

Singletary, Kimberly Alecia

2012-01-01

This article explores the role of the Humanities, Arts, Science, and Technology Advanced Collaboratory (HASTAC) in facilitating and encouraging a collaborative community of junior and senior scholars on issues of technology and humanistic learning. As a result of its emphasis on collaboration and discussion, HASTAC encourages a form of collective…

Developing Values in Primary Classrooms and the Place of the Humanities

ERIC Educational Resources Information Center

Cox, Sue

2017-01-01

In this article, I discuss how the context of children's classroom activities and the quality of their participation and agency are key to learning around values. These pedagogical approaches lie in a socio-cultural theoretical framework which I use to show how "empowered" participation in classrooms and in enquiry activities in…

Forensic Toxicology: An Introduction.

PubMed

Smith, Michael P; Bluth, Martin H

2016-12-01

This article presents an overview of forensic toxicology. The authors describe the three components that make up forensic toxicology: workplace drug testing, postmortem toxicology, and human performance toxicology. Also discussed are the specimens that are tested, the methods used, and how the results are interpreted in this particular discipline. Copyright © 2016 Elsevier Inc. All rights reserved.

Regulations and Ethical Considerations for Astronomy Education Research II: Resources and Worked Examples

ERIC Educational Resources Information Center

Brogt, Erik; Dokter, Erin; Antonellis, Jessie; Buxner, Sanlyn

2008-01-01

This article discusses the legal and ethical requirements of human subjects research proposals in astronomy education research. We present an overview of the relevant laws, regulations, and guidelines that inform an Institutional Review Board evaluation of proposed research. We also present examples of potential research projects in astronomy…

Family Engagement in the Perinatal Period and Infant Rights

ERIC Educational Resources Information Center

Tsantefski, Menka; Humphreys, Cathy; Jackson, Alun C.

2011-01-01

The meaning of human rights for children is a contested issue; the notion of rights for unborn babies poses additional complexity. Drawing on data from a prospective case study of a specialist drug and alcohol obstetric provider and the statutory child protection service, this article discusses family engagement within a child-rights framework,…

Order Information in Working Memory: An Integrative Review of Evidence From Brain and Behavior

ERIC Educational Resources Information Center

Marshuetz, Christy

2005-01-01

Evidence about memory for order information comes from a number of different methodologies: human cognition, patient studies, neuroimaging studies, and animal lesion and behavioral studies. The present article discusses (a) evidence that order and item memory are separable; (b) proposed mechanisms for order memory (interitem associations, direct…

Neoliberalism in the Academic Borderlands: An On-Going Struggle for Equality and Human Rights

ERIC Educational Resources Information Center

Darder, Antonia

2012-01-01

The article examines the negative impact of neoliberal policies upon the work of border intellectuals within the university, whose scholarship seeks to explicitly challenge longstanding structural inequalities and social exclusions. More specifically, the notion of neoliberal multiculturalism is defined and discussed with respect to the phenomenon…

Stories that Teach Life Lessons

ERIC Educational Resources Information Center

Jalongo, Mary

2004-01-01

Children's lives are infused with stories at home, at school or the library, and in the media. This article discusses how to harness the power of literature and use it to develop positive character traits in young children. Storytelling is a fundamental way in which human beings process and share events as well as the feelings surrounding those…

Graphics in Text: A Bibliography. Monograph No. 6.

ERIC Educational Resources Information Center

Macdonald-Ross, Michael; Smith, Eleanor

This bibliography lists books and articles discussing graphic aspects of human communication. References have been selected for their relevance to the design of self-instructional texts for the adult learner; for the most part, research on younger children, on non-text media, and on non-educational texts is not included. Items are organized into…

The Formation of an Ecological Consciousness

ERIC Educational Resources Information Center

Biriukova, N. A.

2005-01-01

In this article, the author discusses how realization of the ideas of humanistic pedagogy and psychology serves as the foundation for the development of value attitudes toward nature and the surrounding world, for the formation of a new type of ecological consciousness. It is obvious that the interaction between human civilization and the earth's…

On "Jensenism": A Reply to Critics.

ERIC Educational Resources Information Center

Jensen, Arthur R.

In this address, Jensen discusses his views on the effects of heredity and environment on human intelligence, in an attempt to clarify his original statements on this subject. Since his article appeared in the "Harvard Educational Review" in 1969, the term "Jensenism" has accrued a variety of meanings through popular usage (according to Jensen)…

The "Tweeting Book" and the Question of "Non-Human Data"

ERIC Educational Resources Information Center

Knox, Jeremy

2015-01-01

This short article describes an experimental radio-frequency identification (RFID) system designed to playfully explore the possibilities of object agency, in the form of "tweeting books". The use of web-enabled sensors is discussed in the context of the emerging field of Learning Analytics. The analysis of the "tweeting books"…

Perceptions of Schooling, Pedagogy and Notation in the Lives of Visually-Impaired Musicians

ERIC Educational Resources Information Center

Baker, David; Green, Lucy

2016-01-01

This article discusses findings on schooling, pedagogy and notation in the life-experiences of amateur and professional visually-impaired musicians/music teachers, and the professional experiences of sighted music teachers who work with visually-impaired learners. The study formed part of a broader UK Arts and Humanities Research Council funded…

Manufacturing in Space: (It's Getting off the Ground!) Resources in Technology.

ERIC Educational Resources Information Center

Technology Teacher, 1988

1988-01-01

Discusses current issues and work on the planned manufacturing Space Station. Such topics as human resources, energy sources, and types of products to be manufactured in space are covered. The possibility of mining other planets for raw materials is considered. Student activities and a quiz covering the article are included. (CH)

Sustainability and the University

ERIC Educational Resources Information Center

Clough, G. Wayne; Chameau, Jean-Lou; Carmichael, Carol

2006-01-01

In this article, the authors state that one of the major challenges facing the human race is charting a course for the future that allows economic growth while protecting the fragile planet. The authors discuss the role that higher education must play to help create a vibrant economy and high quality of life, while sustaining natural resources.…

Use of Self in the Context of Youth Work

ERIC Educational Resources Information Center

Fusco, Dana

2012-01-01

Used in the education of counselors, nurses, occupational therapists and social workers, "use of self" is a way of understanding how practitioners bring about human change. In this article, the author discusses how use of self can be applied to youth work and is related to "developmentally responsive practice" thereby providing a deep theoretical…

How Do Emotions Signify? Social Relations and Psychological Functions in the Dramatic Constitution of Subjects

ERIC Educational Resources Information Center

Magiolino, Lavinia Lopes Salomao; Smolka, Ana Luiza Bustamante

2013-01-01

In this article, we discuss contributions from contemporary authors toward understanding a complex topic: human emotions. We comment on these authors' ideas and describe their ways of talking about emotions in relation to language, consciousness, meaning, and psychological instruments. After considering the distinct contributions of these authors,…

A candid conversation about men, sexual health, and diabetes.

PubMed

Jack, Leonard

2005-01-01

While the profound relationship between human sexuality and diabetes can affect quality of life for both men and women, male sexual health issues in the published literature have primarily focused on physical aspects of erectile dysfunction. The purpose of this article is to move this important discussion regarding aspects of human sexuality and diabetes further to consider the absence of and need for more male-focused research. Attention is given to define and discuss how male perceptions of control and masculinity shape male views on male sex roles. The author offers 4 published explanations to explain factors that influence whether men, regardless of age, nationality, or ethnic group, initiate help-seeking behaviors for sexual health concerns. These explanations can help health care professionals have candid, consistent, and nonjudgmental conversations with their patients and each other. This article concludes with strong recommendations that health care providers engage patients in timely conversations, jointly select and implement tailored treatment options, and, when necessary, link patients with social support systems to maximize improvements in both physical and psychological aspects of sexual health.

Neurodevelopment and Endocrine Disruption

PubMed Central

Colborn, Theo

2004-01-01

In this article I explore the possibility that contaminants contribute to the increasing prevalence of attention deficit hyperactivity disorder, autism, and associated neurodevelopmental and behavioral problems in developed countries. I discuss the exquisite sensitivity of the embryo and fetus to thyroid disturbance and provide evidence of human in utero exposure to contaminants that can interfere with the thyroid. Because it may never be possible to link prenatal exposure to a specific chemical with neurodevelopmental damage in humans, I also present alternate models where associations have been made between exposure to specific chemicals or chemical classes and developmental difficulties in laboratory animals, wildlife, and humans. PMID:15198913

[Digitizing Human and Social Sciences Journals. Recent History and Perspectives].

PubMed

Parisot, Thomas

2015-06-01

Recent years have seen the emergence and the gradual rise of French journals digital offers in the fields of human and social sciences. In this article, we will both reconsider the conditions of occurrence of these services and discuss the evolution of their environment. Through the example of several emerging initiatives in the field of scientific publishing, in a context marked by continuity but also rupture, we will try to glimpse the role journals could play in the new digital world being created.

A comparative psychophysical approach to visual perception in primates.

PubMed

Matsuno, Toyomi; Fujita, Kazuo

2009-04-01

Studies on the visual processing of primates, which have well developed visual systems, provide essential information about the perceptual bases of their higher-order cognitive abilities. Although the mechanisms underlying visual processing are largely shared between human and nonhuman primates, differences have also been reported. In this article, we review psychophysical investigations comparing the basic visual processing that operates in human and nonhuman species, and discuss the future contributions potentially deriving from such comparative psychophysical approaches to primate minds.

[Direct genetic manipulation and criminal code in Venezuela: absolute criminal law void?].

PubMed

Cermeño Zambrano, Fernando G De J

2002-01-01

The judicial regulation of genetic biotechnology applied to the human genome is of big relevance currently in Venezuela due to the drafting of an innovative bioethical law in the country's parliament. This article will highlight the constitutional normative of Venezuela's 1999 Constitution regarding this subject, as it establishes the framework from which this matter will be legally regulated. The approach this article makes towards the genetic biotechnology applied to the human genome is made taking into account the Venezuelan penal law and by highlighting the violent genetic manipulations that have criminal relevance. The genetic biotechnology applied to the human genome has another important relevance as a consequence of the reformulation of the Venezuelan Penal Code discussed by the country's National Assembly. Therefore, a concise study of the country's penal code will be made in this article to better understand what judicial-penal properties have been protected by the Venezuelan penal legislation. This last step will enable us to identify the penal tools Venezuela counts on to face direct genetic manipulations. We will equally indicate the existing punitive loophole and that should be covered by the penal legislator. In conclusion, this essay concerns criminal policy, referred to the direct genetic manipulations on the human genome that haven't been typified in Venezuelan law, thus discovering a genetic biotechnology paradise.

Damned if you do, damned if you don't? The Lundbeck case of pentobarbital, the guiding principles on business and human rights, and competing human rights responsibilities.

PubMed

Buhmann, Karin

2012-01-01

In 2011 it emerged that to induce the death penalty, United States authorities had begun giving injections of pentobarbital, a substance provided by Danish pharmaceutical company Lundbeck. Lundbeck's product pentobarbital is licensed for treatment of refractory forms of epilepsy and for usage as an anaesthetic, thus for a very different purpose. The Lundbeck case offers a difficult, but also interesting Corporate Social Responsibility (CSR) dilemma between choices facing a pharmaceutical company to stop the distribution of a medical substance in order to avoid complicity in human rights violations, or to retain distribution of the substance in order not to impede access to the medicine for those patients who need it. The dilemma arose at a time when the United Nations (UN) Secretary General's Special Representative on Business and Human Rights, Professor John Ruggie, was finalizing a set of Guiding Principles to operationalize recommendations on business and human rights that he had presented to the UN Human Rights Council in 2008. The article discusses the dilemma in which Lundbeck was placed in from the perspective of the Guiding Principles on business and human rights and the 2008 Protect, Respect, Remedy UN Framework. The analysis seeks to assess what guidance may be gauged from the Guiding Principles in relation to the dilemma at hand and discusses the adequacy the Guiding Principles for dealing with acute human rights dilemmas of conflicting requirements in which a decision to avoid one type of violation risks causing violation of another human right. The article concludes by drawing up perspectives for further development of guidance on implementation of the UN Framework that could be considered by the newly established Working Group on Business and Human Rights and related UN bodies. © 2012 American Society of Law, Medicine & Ethics, Inc.

Advances in lithotripsy and stone disease treatment.

PubMed

Newman, J

1996-01-01

Stone disease can be traced back as far as the human record. This article traces the diagnosis and treatment of stone disease from primitive attempts at stone removal in ancient civilizations to the advent of extracorporeal shock wave lithotripsy (ESWL) in the 1970s. ESWL revolutionized the treatment of stone disease, offering patients a less painful alternative to the traditional surgical removal of stones. This article discusses recent advances in ESWL, describes the radiologic technologist's role in diagnosing and managing stone disease, and outlines future prospects in the treatment of stone disease.

The Hand: Shall We Ever Understand How it Works?

PubMed

Latash, Mark L

2015-04-01

The target article presents a review of the neural control of the human hand. The review emphasizes the physical approach to motor control. It focuses on such concepts as equilibrium-point control, control with referent body configurations, uncontrolled manifold hypothesis, principle of abundance, hierarchical control, multidigit synergies, and anticipatory synergy adjustments. Changes in aspects of the hand neural control with age and neurological disorder are discussed. The target article is followed by six commentaries written by Alexander Aruin, Kelly Cole, Monica Perez, Robert Sainburg, Marco Sanello, and Wei Zhang.

An overview of patent law as applied to the field of veterinary medicine.

PubMed

Gould, James M

2008-01-01

This article analyzes some of the challenges that can arise when patent law is applied to the field of veterinary medicine. Topics covered in this article include an overview of the different kinds of inventions that can be patented in the veterinary field; a review of recent legal developments that may affect the patenting of veterinary pharmaceuticals; a discussion of some potential issues related to patents covering assays; and an identification of some special situations where the law affecting veterinary pharmaceuticals is actually different from the law affecting human pharmaceuticals.

[Between mind and body. Psychologicall methods for patients with musculoskeletal pain].

PubMed

Jabłońska-Brzozowska, Judyta

According to the currently prevailing trends in medicine in restoring the psychosomatic unity of human, it is important to ask the question about the function and role of psychology in the rehabilitation of patients with chronic musculoskeletal disorder, MSD. In this article authors present the theoretical basis of psychical and body rehabilitation of patients with MSD. In the first part of this article, problem of the prevalence of MSD in population, its biological, psychological and social components and its impact on the economy of the country, have been discussed. Secondly, there was a focus on the mental representation of the body and its role as a psychophysical integrating unit. The following sections discuss therapeutic methods, like cognitive-behavioral therapy and chosen body work methods as complex rehabilitation of patients with musculoskeletal pain.

IACUC Review of Nonhuman Primate Research

PubMed Central

Tardif, Suzette D.; Coleman, Kristine; Hobbs, Theodore R.; Lutz, Corrine

2013-01-01

This article will detail some of the issues that must be considered as institutional animal care and use committees (IACUCs) review the use of nonhuman primates (NHPs) in research. As large, intelligent, social, long-lived, and non-domesticated animals, monkeys are amongst the most challenging species used in biomedical research and the duties of the IACUC in relation to reviewing research use of these species can also be challenging. Issues of specific concern for review of NHP research protocols that are discussed in this article include scientific justification, reuse, social housing requirements, amelioration of distress, surgical procedures, and humane endpoints. Clear institutional policies and procedures as regards NHP in these areas are critical, and the discussion of these issues presented here can serve as a basis for the informed establishment of such policies and procedures. PMID:24174445

A review of the design and development processes of simulation for training in healthcare - A technology-centered versus a human-centered perspective.

PubMed

Persson, Johanna

2017-01-01

This article reviews literature about simulation systems for training in healthcare regarding the prevalence of human-centered approaches in the design and development of these systems, motivated by a tradition in this field of working technology-centered. The results show that the focus on human needs and context of use is limited. It is argued that a reduction of the focus on technical advancements in favor of the needs of the users and the healthcare community, underpinned by human factors and ergonomics theory, is favorable. Due to the low number of identified articles describing or discussing human-centered approaches it is furthermore concluded that the publication culture promotes technical descriptions and summative evaluations rather than descriptions and reflections regarding the design and development processes. Shifting the focus from a technology-centered approach to a human-centered one can aid in the process of creating simulation systems for training in healthcare that are: 1) relevant to the learning objectives, 2) adapted to the needs of users, context and task, and 3) not selected based on technical or fidelity criteria. Copyright © 2016 Elsevier Ltd. All rights reserved.

Sexuality and spirituality: the relevance of eastern traditions.

PubMed

Francoeur, R T

1992-01-01

This article outlines some of the major Eastern sexual and spiritual traditions (primarily Hinduism, Taoism and Tantrism), and discusses their relevance for the contemporary Western world. The article begins by examining the sources of Eastern sexual traditions, before and after the "Axial" period, the turning point at which male consciousness and power gained ascendancy over the female principle. Although a phallocentric view of the world came to dominate the East, Eastern cultures -- unlike the West -- maintained a respect for nature. According to this view, health and spirituality are gained only when humanity respects its place in the cosmos and lives in harmony with nature. The article then examines the sexual traditions of Hinduism, in which sexual asceticism not only coexisted but also complimented the celebration of sexual desire and pleasure. The article then discusses the Taoist traditions, which, among other things, stressed the importance of female sexual satisfaction. Taoism argued that men cannot experience true sexual ecstasy unless they develop the ability to control their ejaculation. The Tantric sexual tradition, the article explains, maintained that ultimate sexual pleasure would enable one to experience the true nature of reality. The article then goes on to review variations of these traditions: the Hindu Tantric Doctrine (Shaktism), the Buddhist Tantric Doctrine, and Tantra and Yoga. Finally, the article considers the relevance of these Eastern philosophies to the Western sexual tradition, which has tended to view sexuality as antagonistic to spiritual liberation.

The nose between ethics and aesthetics: Sushruta's legacy.

PubMed

Sorta-Bilajac, Iva; Muzur, Amir

2007-11-01

The aim of this article is to determine the origin of interest in rhinoplasty in ancient India, as well as to discuss the ethical and aesthetic implications of the nose in human history. Literature review. Articles on history of medical ethics and rhinoplastic surgery were reviewed. Sushruta is considered "the father of plastic surgery," and ancient India a cradle of rhinoplastic method called "the Indian method." Origin of interest in and need for rhinoplasty is deeply rooted in ancient Indian society due to the practice of nose mutilations as a form of public punishment for immoral conduct. The nose, once symbol of morality expressed through physical integrity, today becomes an important factor of human beauty. Rhinoplastic surgery is, both then and now, deeply pervaded with both ethics and aesthetics.

From sequencing to annotating: extending the metaphor of the book of life from genetics to genomics.

PubMed

Hellsten, Iina

2005-12-01

The article discusses how the metaphor of the Book of Life was extended over time to cover the life cycle of the Human Genome Project from genetics to genomics. In particular, the focus is on the role of extendable metaphors in the debate on the Human Genome Project in three European newspapers, popular scientific journals and scientific and scholarly articles from 1990 to 2002. In these different domains of use, various parts of the metaphor were highlighted. The metaphor of Book of Life was mainly used to justify the continuation of the gene research from gene sequencing to comparative genomics. Readily extendable metaphors, such as the Book of Life, function as useful communicative tools both over time and across domains of use.

[Significance of group A streptococcal infections in human pathology].

PubMed

Cvjetković, Dejan; Jovanović, Jovana; Hrnjaković-Cvjetković, Ivana; Aleksić-Dordević, Mirjana; Stefan-Mikić, Sandra

2008-01-01

Group A streptococci is the causative agent in 80 percents of human streptococcal infections. The only member of this group is Streptococcus pyogenes. CLINICALFEATURES OF GAS INFECTIONS: The various clinical entities and related complications caused by pyogenic streptococci are reviewed in the article. Pharyngitis, scarlet fever, skin and soft tissue infections (pyoderma, cellulitis, perianal dermatitis, necrotising fasciitis) and streptococcal toxic shock syndrome are described. The way of setting the diagnosis including epidemiological data, clinical features and the course of illness, laboratory findings and supportive diagnostic methods are represented in the article. The most important clinical entities which should be discussed in differential diagnosis of diseases caused by pyogenic streptococci are listed. The major principles of etiologic treatment through widely accepted strategies related to first choice antibiotics and alternatives are reviewed.

[The Helsinki Declaration: relativism and vulnerability].

PubMed

Diniz, D; Corrêa, M

2001-01-01

The Helsinki Declaration is a crucial ethical landmark for clinical research involving human beings. Since the Declaration was issued, a series of revisions and modifications have been introduced into the original text, but they have not altered its humanist approach or its international force for regulating clinical research. A proposal for an extensive revision of the Declaration's underlying ethical principles has been debated for the past four years. If the proposal is approved, international clinical research involving human beings will be modified, further increasing the vulnerability of certain social groups. This article discusses the historical process involved in passing the Helsinki Declaration and the most recent debate on the new draft. The article analyzes the new text's social implications for underdeveloped countries, arguing for a political approach to the vulnerability concept.

Latest development of legal regulations of organ transplant in China.

PubMed

Ding, Chunyan

2008-12-01

Organ transplant practice has developed greatly in last two decades in China. In response to the practical need, the State Council released the Regulations on Human Organ Transplant 2007, replacing the previous Interim Provisions on Administration of Clinical Application of Human Organ Transplant Technology 2006. This article first examines the latest development of legal regulations of organ transplant by comparing the differences between the two pieces of legislation. It then analyzes the impact of the new rules set forth in the 2007 Regulations upon three problems existing in the current organ transplant practice, that is, organ procurement from executed prisoners, organ trade, and organ tourism. The article finally discusses the deficiencies of the 2007 Regulations, which are supposed to be remedied in the next legal reform.

The renewal of humanism in psychotherapy: a roundtable discussion.

PubMed

Schneider, Kirk J; Längle, Alfried

2012-12-01

This special section highlights the renewal of humanism in psychotherapy. For the purposes of this special section, humanism is defined as a philosophical perspective whose subject matter is the whole human being. In psychotherapy, humanism places special emphasis on the personal, interpersonal, and contextual dimensions of therapy and on clients' reflections on their relationship with self, others, and the larger psychosocial world. The contributors to this special section-Bruce Wampold, David Elkins, Steven Hayes, Robert Stolorow, Jurgen Kriz, Lillian Comas-Diaz, and the authors of this introduction-are each leaders in their respective therapeutic specialties: research and training, cognitive-behavioral therapy, psychoanalytic therapy, European therapy, and multicultural therapy. In the manner of a "roundtable," each contributor was asked to provide a short article on the renewal of humanism in his or her respective specialty followed by brief comments on the initial round of articles. The conclusion of these reflections is that the renewal of humanism is a viable and growing phenomenon among the leading specialty areas of psychotherapy. The corollary conclusion is that although many theoretical and practical questions remain, humanism is (1) a foundational element of therapeutic effectiveness; (2) a pivotal (and needed) dimension of therapeutic training; and (3) a critical contributor to societal well-being. (c) 2012 APA, all rights reserved.

Human pheromones and sexual attraction.

PubMed

Grammer, Karl; Fink, Bernhard; Neave, Nick

2005-02-01

Olfactory communication is very common amongst animals, and since the discovery of an accessory olfactory system in humans, possible human olfactory communication has gained considerable scientific interest. The importance of the human sense of smell has by far been underestimated in the past. Humans and other primates have been regarded as primarily 'optical animals' with highly developed powers of vision but a relatively undeveloped sense of smell. In recent years this assumption has undergone major revision. Several studies indicate that humans indeed seem to use olfactory communication and are even able to produce and perceive certain pheromones; recent studies have found that pheromones may play an important role in the behavioural and reproduction biology of humans. In this article we review the present evidence of the effect of human pheromones and discuss the role of olfactory cues in human sexual behaviour.

Crew resource management in the ICU: the need for culture change.

PubMed

Haerkens, Marck Htm; Jenkins, Donald H; van der Hoeven, Johannes G

2012-08-22

Intensive care frequently results in unintentional harm to patients and statistics don't seem to improve. The ICU environment is especially unforgiving for mistakes due to the multidisciplinary, time-critical nature of care and vulnerability of the patients. Human factors account for the majority of adverse events and a sound safety climate is therefore essential. This article reviews the existing literature on aviation-derived training called Crew Resource Management (CRM) and discusses its application in critical care medicine. CRM focuses on teamwork, threat and error management and blame free discussion of human mistakes. Though evidence is still scarce, the authors consider CRM to be a promising tool for culture change in the ICU setting, if supported by leadership and well-designed follow-up.

GRAPES—Grounding representations in action, perception, and emotion systems: How object properties and categories are represented in the human brain

PubMed Central

Martin, Alex

2016-01-01

In this article, I discuss some of the latest functional neuroimaging findings on the organization of object concepts in the human brain. I argue that these data provide strong support for viewing concepts as the products of highly interactive neural circuits grounded in the action, perception, and emotion systems. The nodes of these circuits are defined by regions representing specific object properties (e.g., form, color, and motion) and thus are property-specific, rather than strictly modality-specific. How these circuits are modified by external and internal environmental demands, the distinction between representational content and format, and the grounding of abstract social concepts are also discussed. PMID:25968087

Greenlandic water and sanitation-a context oriented analysis of system challenges towards local sustainable development.

PubMed

Hendriksen, Kåre; Hoffmann, Birgitte

2017-08-28

Today, as Greenland focuses on more economic and cultural autonomy, the continued development of societal infrastructure systems is vital. At the same time, pressure is put on the systems by a lack of financial resources and locally based professional competences as well as new market-based forms of organization. Against this background, the article discusses the challenges facing Greenland's self-rule in relation to further develop the existing water and wastewater systems so that they can contribute to the sustainable development of Greenland. The article reviews the historical development of the water supply and wastewater system. This leads to an analysis of the sectorisation, which in recent decades has reorganized the Greenlandic infrastructures, and of how this process is influencing local sustainable development. The article discusses the socio-economic and human impacts and points to the need for developing the water and sanitation system to support not only hygiene and health, but also local sustainable development.

A Dermatologist's Perspective on Vitamin D

PubMed Central

Vanchinathan, Veena; Lim, Henry W.

2012-01-01

Vitamin D is a fat-soluble steroid hormone that is crucial for human health and has recently generated controversy regarding its role in human health and disease. In this Special Article, we discuss our dermatologic perspective on vitamin D in a question-and-answer format. We discuss methods of obtaining vitamin D, including cutaneous photobiosynthesis, diet, and supplements and include the recent US Institute of Medicine recommendations. Other reviewed topics include the associations among skin pigmentation, climate, photoprotection, and vitamin D levels. We also elaborate on the popular interest in sun exposure as a method of normalizing vitamin D levels in the context of the risks of solar and artificial radiation. We also discuss groups at risk for vitamin D inadequacy, the need for testing serum vitamin D levels, and the role of phototherapy in patients with malabsorption conditions and hypervitaminosis D, with a focus on patients with sarcoidosis. Finally, we summarize our recommendations on vitamin D. PMID:22425213

Religious morality (and secular humanism) in Western civilization as precursors to medical ethics: A historic perspective

PubMed Central

Faria, Miguel A.

2015-01-01

In discussing bioethics and the formulation of neuroethics, the question has arisen as to whether secular humanism should be the sole philosophical guiding light, to the exclusion of any discussion (or even mention) of religious morality, in professional medical ethics. In addition, the question has arisen as to whether freedom or censorship should be part of medical (and neuroscience) journalism. Should independent medical journals abstain from discussing certain issues, or should only the major medical journals — i.e., the New England Journal of Medicine (NEJM), the Journal of the American Medical Association (JAMA) or Lancet — be heard, speaking with one “consensual,” authoritative voice? This issue is particularly important in controversial topics impacting medical politics — e.g., public health policy, socio-economics, bioethics, and the so-called redistributive justice in health care. Should all sides be heard when those controversial topics are discussed or only a consensual (monolithic) side? This historical review article discusses those issues and opts for freedom in medical and surgical practice as well as freedom in medical journalism, particularly in opinion pieces such as editorials, commentaries, or letters to the editor, as long as they relate to medicine and, in our special case, to neuroscience and neurosurgery. After answering those questions, and in response to a critical letter to the editor, this review article then expounds comprehensively on the historical and philosophical origins of ethics and religious morality. Necessarily, we discuss the Graeco-Roman legacy and the Judeo-Christian inheritance in the development of ethics and religious morality in Western civilization and their impact on moral conduct in general and on medical and neuroscience ethics in particular. PMID:26110085

Female sex trafficking: conceptual issues, current debates, and future directions.

PubMed

Meshkovska, Biljana; Siegel, Melissa; Stutterheim, Sarah E; Bos, Arjan E R

2015-01-01

Female sex trafficking is a pressing concern. In this article, we provide a comprehensive overview of relevant issues regarding the concept of female sex trafficking and research in the field of human trafficking, drawing on a variety of disciplines, including economics, gender and sexuality studies, psychology, sociology, law, and social work. We discuss the debates surrounding the definition of human trafficking, compare and contrast it with human smuggling, and outline connections between female sex trafficking and the issue of sex work and prostitution. We further discuss the history and current estimations of female sex trafficking. We then outline the main actors in female sex trafficking, including trafficked persons, traffickers, clients, and service providers, and we overview the trafficking process from recruitment to identification, recovery, and (re)integration. Finally, we conclude with recommendations for future research that tie together the concepts of vulnerability, exploitation, and long-term recovery and (re)integration.

Lifeworld-led care: Is it relevant for well-being and the fifth wave of public health action?

PubMed

Hemingway, Ann

2011-01-01

A recent paper has made the case for a "fifth wave" of public health action. The paper articulated the first four waves as focusing on civil engineering, the germ theory of disease, welfare reforms and lifestyle issues. This article will focus on well-being and will expand on the authors' articulation of a current need to "discover a new image of what it is to be human" to begin to address the challenges of promoting well-being. This article will consider an alternative way of viewing human beings within a "caring" context and how this alternative view may aid this potential fifth wave of public health action. This alternative view has emerged from the work of Husserl who suggested that any human view of the world without subjectivity has excluded its basic foundation. The phenomenological understanding of "lifeworld" is articulated through five elements, temporality, spaciality, intersubjectivity, embodiment and mood that are all discussed here in detail. A world of colours, sparkling stars, memories, happiness, joy, anger and sadness. It is this "lifeworld' that when health care or as argued in this article as public health becomes overly focused on decontextualized goals, and measuring quality superficially can be neglected.

Understanding and Responding to Youth Substance Use: The Contribution of a Health and Human Rights Framework

PubMed Central

Gruskin, Sofia; Plafker, Karen; Smith-Estelle, Allison

2001-01-01

This article examines the utility of a health and human rights framework for conceptualizing and responding to the causes and consequences of substance use among young people. It provides operational definitions of “youth” and “substances,” a review of current international and national efforts to address substance use among youths, and an introduction to human rights and the intersection between health and human rights. A methodology for modeling vulnerability in relation to harmful substance use is introduced and contemporary international and national responses are discussed. When governments uphold their obligations to respect, protect, and fulfill human rights, vulnerability to harmful substance use and its consequences can be reduced. PMID:11726374

Human body fluid proteome analysis

PubMed Central

Hu, Shen; Loo, Joseph A.; Wong, David T.

2010-01-01

The focus of this article is to review the recent advances in proteome analysis of human body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar lavage fluid, synovial fluid, nipple aspirate fluid, tear fluid, and amniotic fluid, as well as its applications to human disease biomarker discovery. We aim to summarize the proteomics technologies currently used for global identification and quantification of body fluid proteins, and elaborate the putative biomarkers discovered for a variety of human diseases through human body fluid proteome (HBFP) analysis. Some critical concerns and perspectives in this emerging field are also discussed. With the advances made in proteomics technologies, the impact of HBFP analysis in the search for clinically relevant disease biomarkers would be realized in the future. PMID:17083142

Human body fluid proteome analysis.

PubMed

Hu, Shen; Loo, Joseph A; Wong, David T

2006-12-01

The focus of this article is to review the recent advances in proteome analysis of human body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar lavage fluid, synovial fluid, nipple aspirate fluid, tear fluid, and amniotic fluid, as well as its applications to human disease biomarker discovery. We aim to summarize the proteomics technologies currently used for global identification and quantification of body fluid proteins, and elaborate the putative biomarkers discovered for a variety of human diseases through human body fluid proteome (HBFP) analysis. Some critical concerns and perspectives in this emerging field are also discussed. With the advances made in proteomics technologies, the impact of HBFP analysis in the search for clinically relevant disease biomarkers would be realized in the future.

Germline genome-editing research and its socioethical implications.

PubMed

Ishii, Tetsuya

2015-08-01

Genetically modifying eggs, sperm, and zygotes ('germline' modification) can impact on the entire body of the resulting individual and on subsequent generations. With the advent of genome-editing technology, human germline gene modification is no longer theoretical. Owing to increasing concerns about human germline gene modification, a voluntary moratorium on human genome-editing research and/or the clinical application of human germline genome editing has recently been called for. However, whether such research should be suspended or encouraged warrants careful consideration. The present article reviews recent research on mammalian germline genome editing, discusses the importance of public dialogue on the socioethical implications of human germline genome-editing research, and considers the relevant guidelines and legislation in different countries. Copyright © 2015 Elsevier Ltd. All rights reserved.

Human dignity and human rights in bioethics: the Kantian approach.

PubMed

Rothhaar, Markus

2010-08-01

The concept of human dignity plays an important role in the public discussion about ethical questions concerning modern medicine and biology. At the same time, there is a widespread skepticism about the possibility to determine the content and the claims of human dignity. The article goes back to Kantian Moral Philosophy, in order to show that human dignity has in fact a determinable content not as a norm in itself, but as the principle and ground of human rights and any deontological norms in biomedical ethics. When it comes to defining the scope of human dignity, i.e., the question which entities are protected by human dignity, Kant clearly can be found on the "pro life"-side of the controversy. This, however, is the result of some specific implications of Kant's transcendental approach that may be put into question.

Women trafficked into prostitution: determinants, human rights and health needs.

PubMed

Gajic-Veljanoski, Olga; Stewart, Donna E

2007-09-01

Human trafficking is an international challenge that increasingly affects industrialized countries. It represents a gross violation of a person's right to liberty and freedom of movement, and is often accompanied by violence and degrading treatment which can have detrimental effects on health. In this article, we review the definition and extent of human trafficking, and focus on the human rights abuses and determinants of trafficking in women. Mental health and other health outcomes are reviewed, and differences between countries in organized activities for victim assistance and protection are assessed. Finally, we discuss the roles of mental health and other healthcare providers in identifying and helping trafficked women, and recommend a tailored multidisciplinary approach for victim assistance.

The big challenges in modeling human and environmental well-being.

PubMed

Tuljapurkar, Shripad

2016-01-01

This article is a selective review of quantitative research, historical and prospective, that is needed to inform sustainable development policy. I start with a simple framework to highlight how demography and productivity shape human well-being. I use that to discuss three sets of issues and corresponding challenges to modeling: first, population prehistory and early human development and their implications for the future; second, the multiple distinct dimensions of human and environmental well-being and the meaning of sustainability; and, third, inequality as a phenomenon triggered by development and models to examine changing inequality and its consequences. I conclude with a few words about other important factors: political, institutional, and cultural.

Assisting victims of human trafficking: strategies to facilitate identification, exit from trafficking, and the restoration of wellness.

PubMed

Hodge, David R

2014-04-01

Human trafficking is a pressing social justice concern. Social work is uniquely situated to address this problem. However, despite the profession's commitment to social justice, the scholarship to equip social workers to address this issue has been largely absent from professional discourse. To address this gap, this article helps social work practitioners to assist victims of human trafficking. After orienting readers to the scope and process of human trafficking, the topics of victim identification, exit from trafficking, and the restoration of psychological wellness are discussed. By equipping themselves in these three areas, practitioners can advance social justice on behalf of some of the most exploited people in the world.

Reflections on human rights as a reality for women and midwives.

PubMed

Murphy-Lawless, Jo

2015-10-01

We often speak of a woman's right to choose the way she wishes to give birth. This article discusses how 'real' that right is. Some of the legal background to human rights as they relate to childbirth is set out, centred on the 2010 European Court of Human Rights ruling in the home birth case, Ternovszky v Hungary. The limitations of this case point to why resorting to the law to achieve their rights about birth may not be the most fruitful remedy for women. Instead the argument is made for creating equality of voice in the clinical area to achieve a stronger collective voice for anchoring human rights in practice.

Breast milk donation after neonatal death in Australia: a report.

PubMed

Carroll, Katherine E; Lenne, Brydan S; McEgan, Kerri; Opie, Gillian; Amir, Lisa H; Bredemeyer, Sandra; Hartmann, Ben; Jones, Rachel; Koorts, Pieter; McConachy, Helen; Mumford, Patricia; Polverino, Jan

2014-01-01

Lactation and breast milk can hold great value and meaning for grieving mothers who have experienced a recent death of an infant. Donation to a human milk bank (HMB) as an alternative to discarding breast milk is one means of respecting the value of breast milk. There is little research, national policy discussion, or organizational representation in Australia on the subject of breast milk donation after infant death. On 29 November 2013 the Mercy Hospital for Women in Melbourne, Australia hosted Australia's first National Stakeholder Meeting (NSM) on the topic of milk donation after neonatal death. The NSM drew together representatives from Australian HMBs, neonatal intensive care units (NICUs) currently using donor human milk, and Australia's chief NICU parent support organization. The NSM was video-recorded and transcribed, and analyzed thematically by researchers. This article reports the seven dominant themes discussed by stakeholders during the NSM: the spectrum of women's lactation and donation experiences after infant death; the roles of the HMB and NICU in meeting the needs of the bereaved donor; how bereaved mothers' lactation autonomy may interface with a HMB's donation guidelines; how milk donation may be discussed with bereaved mothers; the variation between four categories of milk donation after neonatal death; the impact of limited resources and few HMBs on providing donation programs for bereaved mothers in Australia. This article provides evidence from researchers and practitioners that can assist HMB staff in refining their bank's policy on milk donation after infant death, and provides national policy makers with key considerations to support lactation, human milk banking, and bereavement services nation-wide.

Vesicle coating and uncoating: controlling the formation of large COPII-coated carriers

PubMed Central

Townley, Anna K

2009-01-01

The basic mechanisms underlying the formation of coated vesicles are now defined in considerable detail. This article highlights recent developments in our understanding of the problem of exporting large macromolecular cargo such as procollagen from the endoplasmic reticulum and discusses the implications that this has for cell and tissue organisation and human disease. PMID:20401317

Vesicle coating and uncoating: controlling the formation of large COPII-coated carriers.

PubMed

Townley, Anna K; Stephens, David J

2009-08-26

The basic mechanisms underlying the formation of coated vesicles are now defined in considerable detail. This article highlights recent developments in our understanding of the problem of exporting large macromolecular cargo such as procollagen from the endoplasmic reticulum and discusses the implications that this has for cell and tissue organisation and human disease.

Does History Matter? Ask the Armenians

ERIC Educational Resources Information Center

Totten, Samuel

2005-01-01

This article discusses the history of the Armenian genocide and the impact it brought on the Armenians. The author relates his experience attending a two-day memorial commemoration in the desert of Syria for the 90th anniversary of the Armenian genocide that he became fully aware of how profound the memory of that human disaster is for today's…

Effect of Open Note Quizzes on Community College Science Students Grades and Attrition Rates

ERIC Educational Resources Information Center

Gannon, Maureen N.; Abdullahi, Abass S.

2013-01-01

This article describes the effectiveness of open note quizzes in improving student outcomes in an introductory Human Anatomy and Physiology course. Results are discussed within the context of a teaching strategy called LETME (Link, Extract, Transform, Monitor and Extend), which was specifically developed for at risk community college students. The…

Your IRB: Educating Students, Monitoring Student Research, and Safeguarding Students as Research Subjects

ERIC Educational Resources Information Center

Scheppler, Judy; Kolar, Christopher

2008-01-01

This article informs about the formation of a school's Institutional Review Board (IRB), presents examples of research that IRBs often encounter, elevates awareness of human subjects research concerns for faculty and staff, and discusses how emerging requirements for science competitions may affect schools, staff and students. An IRB is the group…

The Production and Destruction of Individual Competence: The Role of Vocational Experience

ERIC Educational Resources Information Center

Suleman, Fatima; Paul, Jean-Jacques

2007-01-01

This article presents the results of research into the impact on individual skill levels of the variables traditionally represented by human capital. The discussion is centred around the way in which education and vocational experience contribute to the process of producing useful skills in the job market or, conversely, of making them obsolete.…

Visions Lost and Dreams Forgotten: Environmental Education, Systems Thinking, and Possible Futures in American Public Schools

ERIC Educational Resources Information Center

Cassell, John A.; Nelson, Thomas

2010-01-01

This article discusses the contributions to this special issue of "Teacher Education Quarterly." At the core of all the contributions is the compellingly urgent realization that humanity is facing, and must deal with, enormous ecological and social problems and challenges. This situation has created an urgent and compelling need centered…

Turning Ideologies inside Out: Developing Young Readers' Empathy for Critical Voices in Narrative Fiction

ERIC Educational Resources Information Center

Pereira, Íris Susana Pires; Campos, Ângela

2014-01-01

This article is located at the crossroads between two distinctive human traits, empathy and rational thought, with narrative emerging as a particularly powerful means to enable young readers to bring them together. Specifically, we discuss the role that critical literary exegesis plays in the development of empathic consciousness in literary…

Self-Regulated Learning in Learning Environments with Pedagogical Agents that Interact in Natural Language

ERIC Educational Resources Information Center

Graesser, Arthur; McNamara, Danielle

2010-01-01

This article discusses the occurrence and measurement of self-regulated learning (SRL) both in human tutoring and in computer tutors with agents that hold conversations with students in natural language and help them learn at deeper levels. One challenge in building these computer tutors is to accommodate, encourage, and scaffold SRL because these…

Case Studies in Critical Ecoliteracy: A Curriculum for Analyzing the Social Foundations of Environmental Problems

ERIC Educational Resources Information Center

Turner, Rita; Donnelly, Ryan

2013-01-01

This article outlines the features and application of a set of model curriculum materials that utilize eco-democratic principles and humanities-based content to cultivate critical analysis of the cultural foundations of socio-environmental problems. We first describe the goals and components of the materials, then discuss results of their use in…

Human Identities and Nation Building: Comparative Analysis, Markets, and the Modern University

ERIC Educational Resources Information Center

Callejo Pérez, David; Hernández Ulloa, Abel; Martínez Ruiz, Xicoténcatl

2014-01-01

The purpose of this article is to discuss the dilemma of the multi-university in sustainable education, research, and outreach by addressing some of the ways in which universities, must generate actions that seek to address these challenges, develop strategic relationships, and maximize their potential in the areas of teaching, research and…

Animal Research in Higher Education: Engaging the Moral and Ethical Conversation

ERIC Educational Resources Information Center

Dolby, Nadine

2017-01-01

Faculty and staff are rightly concerned with the moral and ethical dimensions of human relationships on campus. Yet, they rarely discuss the animals with whom they share their campuses and larger world. In this article, the author reflects on her experience on an Institutional Animal Care and Use Committee to raise questions about animals in…

International Union for Conservation of Nature Bulletin (IUCN), Volume 3 Number 2.

ERIC Educational Resources Information Center

IUCN Bulletin, 1972

1972-01-01

Compiled in this newsletter are activities, viewpoints, reports, and publications of the International Union for Conservation of Nature and Natural Resources (IUCN). The principal article in this issue is a discussion of land use, one of the major forces contributing to the crisis of the human environment in addition to population and pollution.…

The Exploitative Nature of Work-Based Studies: A Sketch of an Idea

ERIC Educational Resources Information Center

Gibbs, Paul

2004-01-01

This article argues that, if education is considered as a means of increasing human capital, then the potential exists for exploitation of the learners through the inequitable distribution of the value accruing from their research activities. To illustrate the argument, I discuss these issues through the lens of a work-based professional doctorate…

Wellbeing in the Classroom: How an Evolutionary Perspective on Human Musicality Can Inform Music Education

ERIC Educational Resources Information Center

Maury, Susan; Rickard, Nikki

2016-01-01

Group singing is a common feature of classroom-based music education, and has often been proposed to have benefits that extend beyond acquisition of music skills, primarily in academic achievement. However, potential social and emotional well-being benefits have been under-represented in these discussions. This article proposes that an…

A Shared Vision of Human Excellence: Confucian Spirituality and Arts Education

ERIC Educational Resources Information Center

Tan, Charlene; Tan, Leonard

2016-01-01

Spirituality encourages the individual to make sense of oneself within a wider framework of meaning and see oneself as part of some larger whole. This article discusses Confucian spirituality by focusing on the spiritual ideals of "dao" (Way) and "he" (harmony). It is explained that the Way represents a shared vision of human…

Belief, Knowledge and Understanding: How to Deal with the Relations between Different Cultural Perspectives in Classrooms

ERIC Educational Resources Information Center

Moreira-dos-Santos, Frederik; El-Hani, Charbel N.

2017-01-01

This article discusses how to deal with the relations between different cultural perspectives in classrooms, based on a proposal for considering understanding and knowledge as goals of science education, inspired by Dewey's naturalistic humanism. It thus combines educational and philosophical interests. In educational terms, our concerns relate to…

EKISTICS [OIKIETIKH]: The Problem and Science of Human Settlements, Volume 41, Number 246, May 1976. Education.

ERIC Educational Resources Information Center

Bell, Gwen, Ed.

Articles related to educational planning in developing nations are presented. This issue of the journal of the World Society for Ekistics reviews environmental and settlement education programs which offer a wide variety of new approaches. Topics discussed include becoming a planning society; challenges, dilemmas, and strategies of ekistics…

A Walk on the Human Performance Side--Part 1

ERIC Educational Resources Information Center

Addison, Roger M.; Haig, Carol

2012-01-01

Using their "license to snoop," performance architects uncover the nuances of how work gets done in an organization. This is the first of a four-part series in which each article will present a different organizational level. Typical performance issues and opportunities for each level will be discussed, and helpful models and tools will be shared.…

Age and ageism: inhabiting the lives of healthy older adults through video narratives.

PubMed

Walker, Charles A; Newcomb, Patty; Cagle, Carolyn

2005-06-01

When applied humanities is used as a framework, the educational innovation described in this article provides a more balanced view of aging than occurs in most nursing programs. Five video narratives and focused discussion questions, intended to mitigate the "otherness" of old age, are described. Rationales and sample student responses are provided.

Indigenous Education in Brazil: The Issue of Contacted and Noncontacted Native Indians

ERIC Educational Resources Information Center

Guilherme, Alexandre

2015-01-01

The Universal Declaration of Human Rights states that "everyone has the right to education" and "elementary education shall be compulsory." In this article, I first discuss the current situation of Native Indian education in Brazil; this is to say, the education of the so-called contacted groups. I shall make clear that the…

In Search of Ecopedagogy: Emplacing Nature in the Light of Proust and Thoreau

ERIC Educational Resources Information Center

Hung, Ruyu

2014-01-01

In this article I intend to explore one possible way of using "place" to rethink "nature," the relationship between humans and nature, and the implications for education. The elucidation and discussion of the sense of place will reveal that there are profound and superficial or, placeful and placeless, senses of place. This…

PESTE Factors in Developing a Framework for E-Learning

ERIC Educational Resources Information Center

Graham, Deryn

2007-01-01

This article describes the development of a framework for e-learning and presents the findings of a study investigating whether the use of blended learning can fulfil or at least accommodate some of the human requirements presently neglected by current e-learning systems. The study evaluated the in-house system, Teachmat, and discussed how the use…

The biology of human immunodeficiency virus infection.

PubMed

Kotler, Donald P

2004-08-01

The aim of this article is to review the basic biology of infection with HIV-1 and the development of the acquired immunodeficiency syndrome. The discussion will include epidemiology, general description of the retroviruses, pathogenesis of the immune deficiency, clinical consequences, treatment, and treatment outcomes. Aspects of the infection that affect protein and energy balance will be identified.

Invited Reaction: Birds of a Feather? HRD and Business Schools Should Flock Together

ERIC Educational Resources Information Center

May, Gary L.

2007-01-01

Peter Kuchinke has written a powerful and relevant article that should generate much discussion in the human resource development (HRD) community. The focus of Kuchinke's paper is the question of whether HRD academic programs should emulate the value preference of business schools or march to a different drum. In this response, the author argues…

I Heard This Great Math Story the Other Day!

ERIC Educational Resources Information Center

Gadanidis, George

2009-01-01

In this article, the author declares that if a student is able to discuss school math with family and friends just like one would a new movie, then that student has experienced meaningful math learning and teaching. With the support of the Social Sciences and Humanities Research Council, the author is presently working in K-8 classrooms, offering…

Associated morbidities to congenital diaphragmatic hernia and a relationship to human milk.

PubMed

Froh, Elizabeth B; Spatz, Diane L

2012-08-01

The majority of what is known in the recent literature regarding human milk studies in the neonatal intensive care setting is specific to term and/or preterm infants (including very-low-birth-weight preterm infants). However, there is a lack of human milk and breastfeeding literature concerning infants with congenital anomalies, specifically infants diagnosed with congenital diaphragmatic hernia (CDH). By applying human milk research conducted among other populations of infants, this article highlights how human milk may have a significant impact on infants with CDH. Recent human milk studies are reviewed and then applied to the CDH population in regard to respiratory and gastrointestinal morbidities, as well as infection and length of stay. In addition, clinical implications of these relationships are discussed and suggestions for future research are presented.

Communication as a human right: Citizenship, politics and the role of the speech-language pathologist.

PubMed

Murphy, Declan; Lyons, Rena; Carroll, Clare; Caulfield, Mari; De Paor, Gráinne

2018-02-01

According to Article 19 of the Universal Declaration on Human Rights "Everyone has the right to freedom of opinion and expression; this right includes freedom to hold opinions without interference and to seek, receive and impart information and ideas through any media and regardless of frontiers." The purpose of this paper is to elucidate communication as a human right in the life of a young man called Declan who has Down syndrome. This commentary paper is co-written by Declan, his sister who is a speech-language pathologist (SLP) with an advocacy role, his SLP, and academics. Declan discusses, in his own words, what makes communication hard, what helps communication, his experiences of speech-language pathology, and what he knows about human rights. He also discusses his passion for politics, his right to be an active citizen and participate in the political process. This paper also focuses on the role of speech-language pathology in supporting and partnering with people with communication disabilities to have their voices heard and exercise their human rights.

Influence of Human Factor Issues on Patient-Centered mHealth Apps' Impact; Where Do We Stand?

PubMed

Wildenbos, G A; Peute, L W; Jaspers, M W M

2016-01-01

This paper discusses the preliminary results of a literature review on studies published in 2014-2015 concerning patient-centered mHealth applications' (apps) impact. Abstracts were included when they described a mHealth app targeted at patients and reported on the effects of this app on patient care. From a total of 559 potentially relevant articles, 17 papers were finally included. Nine studies reported a positive impact of the patient-centered mHealth app on patient care; 4 of these studies were randomized controlled trials. Measured impacts in the 17 studies focused on improving patients' physical activity, self-efficacy and medication adherence. Human factors issues potentially mediating these effects were discussed in all studies. Transitions in the interaction between healthcare providers and their patients were most often discussed as influencing the impact of the mHealth app. More research is needed, focussing on human issues mediating the effect of patient-centered mHealth apps to precipitate knowledge on the effectiveness of mHealth. This research should preferably be guided by socio-technical models.

The lung microbiome in health and disease.

PubMed

Moffatt, Miriam F; Cookson, William Ocm

2017-12-01

The Human Microbiome Project began 10 years ago, leading to a significant growth in understanding of the role the human microbiome plays in health and disease. In this article, we explain with an emphasis on the lung, the origins of microbiome research. We discuss how 16S rRNA gene sequencing became the first major molecular tool to examine the bacterial communities present within the human body. We highlight the pitfalls of molecular-based studies, such as false findings resulting from contamination, and the limitations of 16S rRNA gene sequencing. Knowledge about the lung microbiome has evolved from initial scepticism to the realisation that it might have a significant influence on many illnesses. We also discuss the lung microbiome in the context of disease by giving examples of important respiratory conditions. In addition, we draw attention to the challenges for metagenomic studies of respiratory samples and the importance of systematic bacterial isolation to enable host-microbiome interactions to be understood. We conclude by discussing how knowledge of the lung microbiome impacts current clinical diagnostics. © Royal College of Physicians 2017. All rights reserved.

Whose body is it anyway? Human cells and the strange effects of property and intellectual property law.

PubMed

Feldman, Robin

2011-06-01

Whatever else I might own in this world, it would seem intuitively obvious that I own the cells of my body. Where else could the notion of ownership begin, other than with the components of the tangible corpus that all would recognize as "me"? The law, however, does not view the issue so neatly and clearly, particularly when cells are no longer in my body. As so often happens in law, we have reached this point, not by design, but by the piecemeal development of disparate notions that, when gathered together, form a strange and disconcerting picture. This Article examines both property and intellectual property doctrines in relation to human cells that are no longer within the body. In particular, the Article discusses the Bilski decision, in the context of life science process patents, and the Molecular Pathology case, in the context of gene patents. For patent law, the Article concludes that the problem lies not with the fact that genes constitute patentable subject matter, but rather with the extent of the rights that are granted. For both property and intellectual property law, the Article concludes that a more careful application of basic legal principles would better reflect the interests of society as a whole and the interests of individual human subjects, as well as the interests of those who innovate.

Recent developments in affective recommender systems

NASA Astrophysics Data System (ADS)

Katarya, Rahul; Verma, Om Prakash

2016-11-01

Recommender systems (RSs) are playing a significant role since 1990s as they provide relevant, personalized information to the users over the internet. Lots of work have been done in information filtering, utilization, and application related to RS. However, an important area recently draws our attention which is affective recommender system. Affective recommender system (ARS) is latest trending area of research, as publication in this domain are few and recently published. ARS is associated with human behaviour, human factors, mood, senses, emotions, facial expressions, body gesture and physiological with human-computer interaction (HCI). Due to this assortment and various interests, more explanation is required, as it is in premature phase and growing as compared to other fields. So we have done literature review (LR) in the affective recommender systems by doing classification, incorporate reputed articles published from the year 2003 to February 2016. We include articles which highlight, analyse, and perform a study on affective recommender systems. This article categorizes, synthesizes, and discusses the research and development in ARS. We have classified and managed ARS papers according to different perspectives: research gaps, nature, algorithm or method adopted, datasets, the platform on executed, types of information and evaluation techniques applied. The researchers and professionals will positively support this survey article for understanding the current position, research in affective recommender systems and will guide future trends, opportunity and research focus in ARS.

The association between phthalate exposure and atopic dermatitis with a discussion of phthalate induced secretion of interleukin-1β and thymic stromal lymphopoietin.

PubMed

Overgaard, Line E K; Bonefeld, Charlotte M; Frederiksen, Hanne; Main, Katharina M; Thyssen, Jacob P

2016-06-01

Phthalate diesters are widely used as emollients in plastic and cosmetics as well as in food packaging and perfumes, potentially leading to prolonged and repeated dermal, oral and airborne exposure. We here review published articles that have evaluated the putative role of phthalate diesters in the pathogenesis of atopic dermatitis and discuss possible pathogenic pathways. A literature search resulted in 563 articles in Embase and 263 articles in Pubmed. After identification of relevant articles based on screening of titles, abstracts and reference lists, a total of 39 articles were selected and included. While no clear association has been shown between systemic phthalate levels and atopic dermatitis in human studies, animal data suggests that phthalates may worsen dermatitis and in vitro data suggests that interleukin-4 could be upregulated. Moreover, both loss-of-function mutations in the filaggrin gene and atopic dermatitis have been associated with elevated systemic phthalate levels. There is a need for prospective studies to clarify the possible pathogenic role of phthalate diesters in atopic dermatitis and the associated health risk, especially with the general trend towards barrier restoration with emollients in infants at risk of developing atopic dermatitis. In summary, we conclude that the results from published studies are controversial and inconclusive.

From bioethics to a sociology of bio-knowledge.

PubMed

Petersen, Alan

2013-12-01

Growing recognition of bioethics' shortcomings, associated in large part with its heavy reliance on abstract principles, or so-called principlism, has led many scholars to propose that the field should be reformed or reconceptualised. Principlism is seen to de-contextualise the process of ethical decision-making, thus restricting bioethics' contributions to debate and policy on new and emergent biotechnologies. This article examines some major critiques of bioethics and argues for an alternative normative approach; namely, a sociology of bio-knowledge focussing on human rights. The article discusses the need for such an approach, including the challenges posed by the recent rise of 'the bio-economy'. It explores some potential alternative bases for a normative sociology of bio-knowledge, before presenting the elements of the proposed human rights-focused approach. This approach, it is argued, will benefit from the insights and concepts offered by various fields of critical scholarship, particularly the emergent sociology of human rights, science and technology studies, Foucaultian scholarship, and feminist bioethics. Copyright © 2013 Elsevier Ltd. All rights reserved.

Recent advances in CMV tropism, latency, and diagnosis during aging.

PubMed

Leng, Sean X; Kamil, Jeremy; Purdy, John G; Lemmermann, Niels A; Reddehase, Matthias J; Goodrum, Felicia D

2017-06-01

Human cytomegalovirus (CMV) is one of the largest viruses known to cause human diseases. Chronic CMV infection, as defined by anti-CMV IgG serology, increases with age and is highly prevalent in older adults. It has complex biology with significant immunologic and health consequences. This article aims to summarize research findings presented at the 6th International Workshop on CMV and Immunosenescence that relate to advances in the areas of CMV tropism, latency, CMV manipulation of cell metabolism, and T cell memory inflation, as well as novel diagnostic evaluation and translational research of chronic CMV infection in older adults. Information summarized here represents the current state of knowledge in these important fields. Investigators have also identified a number of areas that deserve further and more in-depth investigation, including building more precise parallels between mouse CMV (mCMV) and human CMV (HCMV) research. It is hoped that this article will also stimulate engaging discussion on strategies and direction to advance the science to the next level.

Implications of human trafficking in Asia: a scoping review of aftercare initiatives centered on economic development.

PubMed

Camp, Meghan A; Barner, John R; Okech, David

2018-01-01

The trafficking of persons is one of the most egregious violations of human rights in modern society. Given the disproportionate effects across demographic categories of age and gender, as well as concentrated impacts within the developing world, there is a strong need for research and literature on program effectiveness and appropriate aftercare efforts for those persons whose lives and livelihoods have been impacted by trafficking. The purpose of this article is to provide a scoping review of what is known about effectively helping survivors of human trafficking experiencing lack of economic opportunity and the implications for practice and future research regarding the absence of literature. From over 14,000 initial search results, this article focuses on those initiatives (N = 16) that support economic development of the individual or family after being trafficked. Implications arising from the review for trafficking policy, areas for further research, and implications for practitioners are highlighted and discussed.

Ethical issues regarding human cloning: a nursing perspective.

PubMed

Dinç, Leyla

2003-05-01

Advances in cloning technology and successful cloning experiments in animals raised concerns about the possibility of human cloning in recent years. Despite many objections, this is not only a possibility but also a reality. Human cloning is a scientific revolution. However, it also introduces the potential for physical and psychosocial harm to human beings. From this point of view, it raises profound ethical, social and health related concerns. Human cloning would have an impact on the practice of nursing because it could result in the creation of new physiological and psychosocial conditions that would require nursing care. The nursing profession must therefore evaluate the ethics of human cloning, in particular the potential role of nurses. This article reviews the ethical considerations of reproductive human cloning, discusses the main reasons for concern, and reflects a nursing perspective regarding this issue.

Critical linkages between land-use transition and human health in the Himalayan region.

PubMed

Xu, Jianchu; Sharma, Rita; Fang, Jing; Xu, Yufen

2008-02-01

This article reviews critical linkages between land-use transition and human health in the Himalayan region by applying ecosystem approaches to human health (or EcoHealth). Land-use transition in the Himalayan and similar regions includes sedentarization, agricultural intensification, habitat modification, migration, change of livelihoods and lifestyles, biodiversity loss, and increasing flash floods. These transitions, which can have impacts on human health, are driven by state policies, a market economy, and climate change. Human health is dependent on access to ecosystem services for food, nutrition, medicine, fiber and shelter, fresh water, and clear air. Ecosystem management has been a key means of controlling disease vectors and creating suitable habitats for human well-being. The paper identifies the web of environmental factors that influence human health. Institutional and policy issues for land-use and health transitions are also discussed.

Standard Mutation Nomenclature in Molecular Diagnostics

PubMed Central

Ogino, Shuji; Gulley, Margaret L.; den Dunnen, Johan T.; Wilson, Robert B.

2007-01-01

To translate basic research findings into clinical practice, it is essential that information about mutations and variations in the human genome are communicated easily and unequivocally. Unfortunately, there has been much confusion regarding the description of genetic sequence variants. This is largely because research articles that first report novel sequence variants do not often use standard nomenclature, and the final genomic sequence is compiled over many separate entries. In this article, we discuss issues crucial to clear communication, using examples of genes that are commonly assayed in clinical laboratories. Although molecular diagnostics is a dynamic field, this should not inhibit the need for and movement toward consensus nomenclature for accurate reporting among laboratories. Our aim is to alert laboratory scientists and other health care professionals to the important issues and provide a foundation for further discussions that will ultimately lead to solutions. PMID:17251329

[Magical and religious healing in Byzantium].

PubMed

Józsa, László

2010-01-01

Religious and magical ways of healing have been known and practiced since the very beginning of human history. In the present article, the Byzantine philosophical, cultural, historical and "methodological" aspects of this way of healing are discussed. The article outlines the development of magic healing in Byzantium from the 4th to the 15th century. During this period magical therapy included the cult of patron saints--listed by the author--and pleading for divine intervention as well. The activity of "anargyroi" and the use of magical objects and amulets is also discussed in detail. Exorcism was also a part of religious therapy both against psychical and somatical diseases. In early Christianity, and especially in Byzantium the devil or other demons were also supposed to cause various somatical or psychical illnesses by "intrusion" or "internalisation," i.e. by possession or obsession of their victims.

Health professionals and human rights campaigners: different cultures, shared goals.

PubMed

Sheather, J

2009-03-01

This article looks at a disagreement that emerged at an international human rights conference between health professionals and human rights activists. The disagreement centred on the scope of the responsibilities of health professionals in relation to potential systemic human rights violations. In this article, the nature of the disagreement that emerged at the conference is explored. It is first situated in relation to a strong shared commitment to the "right of everyone to the highest attainable standard of physical and mental health"--often shortened to "the right to health" as it appears in the International Covenant on Economic, Social and Cultural Rights (ICESCR). Some of the tensions that emerged between the participants are then looked at and some of the causes of apparent disagreement identified. The relevance of human rights to health professionals and their impact on medical practice are discussed. Finally, it is argued that, given the common interests shared by these groups, the misunderstandings are not substantive and that there is real scope for mutual learning and collaboration. Although the conference was in southern Asia, the lessons learnt are applicable anywhere in the world--they are equally as relevant to the UK and Europe as to developing countries in the south.

Occupational and public health considerations for work-hour limitations policy regarding public health workers during response to natural and human-caused disasters.

PubMed

Berkowitz, Murray R

2012-01-01

This article examines the occupational health considerations that might impact the health and wellbeing of public health workers during responses to natural (eg, floods and hurricanes) and human-caused (eg, terrorism, war, and shootings) disasters. There are a number of articles in the medical literature that argue the impact of how working long hours by house staff physicians, nurses, and first-responders may pose health and safety concerns regarding the patients being treated. The question examined here is how working long hours may pose health and/or safety concerns for the public health workers themselves, as well as to those in the communities they serve. The health problems related to sleep deprivation are reviewed. Current policies and legislations regarding work-hour limitations are examined. Policy implications are discussed.

Natural Good Theories and the Value of Human Dignity.

PubMed

Muders, Sebastian

2016-04-01

One of the widely recognized facts about human dignity is its vastly divergent applicability-from highly controversial issues in bioethics to broader topics in political philosophy. A group of theories that this article subsumes under the header "natural good theories" appears to be especially fitted for normatively multifaceted notions like dignity. However, the heavy normative weight the concept of dignity has to bear due to the central position it occupies within these theories creates its own difficulties. As is shown in a discussion of Martha Nussbaum's capability conception of dignity, dignity appears to be unable to mirror the special normative relevance people want to assign to it in cases of great moral misconduct. The article provides a suggestion on how to solve this problem by means of paradigmatic cases that work as material constraints regarding the exact boundaries of dignity violations.

DeTEXT: A Database for Evaluating Text Extraction from Biomedical Literature Figures

PubMed Central

Yin, Xu-Cheng; Yang, Chun; Pei, Wei-Yi; Man, Haixia; Zhang, Jun; Learned-Miller, Erik; Yu, Hong

2015-01-01

Hundreds of millions of figures are available in biomedical literature, representing important biomedical experimental evidence. Since text is a rich source of information in figures, automatically extracting such text may assist in the task of mining figure information. A high-quality ground truth standard can greatly facilitate the development of an automated system. This article describes DeTEXT: A database for evaluating text extraction from biomedical literature figures. It is the first publicly available, human-annotated, high quality, and large-scale figure-text dataset with 288 full-text articles, 500 biomedical figures, and 9308 text regions. This article describes how figures were selected from open-access full-text biomedical articles and how annotation guidelines and annotation tools were developed. We also discuss the inter-annotator agreement and the reliability of the annotations. We summarize the statistics of the DeTEXT data and make available evaluation protocols for DeTEXT. Finally we lay out challenges we observed in the automated detection and recognition of figure text and discuss research directions in this area. DeTEXT is publicly available for downloading at http://prir.ustb.edu.cn/DeTEXT/. PMID:25951377

Los Alamos Science: The Human Genome Project. Number 20, 1992

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cooper, N G; Shea, N

1992-01-01

This article provides a broad overview of the Human Genome Project, with particular emphasis on work being done at Los Alamos. It tries to emphasize the scientific aspects of the project, compared to the more speculative information presented in the popular press. There is a brief introduction to modern genetics, including a review of classic work. There is a broad overview of the Genome Project, describing what the project is, what are some of its major five-year goals, what are major technological challenges ahead of the project, and what can the field of biology, as well as society expect tomore » see as benefits from this project. Specific results on the efforts directed at mapping chromosomes 16 and 5 are discussed. A brief introduction to DNA libraries is presented, bearing in mind that Los Alamos has housed such libraries for many years prior to the Genome Project. Information on efforts to do applied computational work related to the project are discussed, as well as experimental efforts to do rapid DNA sequencing by means of single-molecule detection using applied spectroscopic methods. The article introduces the Los Alamos staff which are working on the Genome Project, and concludes with brief discussions on ethical, legal, and social implications of this work; a brief glimpse of genetics as it may be practiced in the next century; and a glossary of relevant terms.« less

Tissue engineering in urethral reconstruction—an update

PubMed Central

Mangera, Altaf; Chapple, Christopher R

2013-01-01

The field of tissue engineering is rapidly progressing. Much work has gone into developing a tissue engineered urethral graft. Current grafts, when long, can create initial donor site morbidity. In this article, we evaluate the progress made in finding a tissue engineered substitute for the human urethra. Researchers have investigated cell-free and cell-seeded grafts. We discuss different approaches to developing these grafts and review their reported successes in human studies. With further work, tissue engineered grafts may facilitate the management of lengthy urethral strictures requiring oral mucosa substitution urethroplasty. PMID:23042444

Neuropsychiatry of creativity.

PubMed

Mula, Marco; Hermann, Bruce; Trimble, Michael R

2016-04-01

In this paper, we review in brief the development of ideas that over time have tried to explain why some individuals are more creative than others and what may be the neurobiological links underlying artistic creativity. We note associations with another unique human idea, that of genius. In particular, we discuss frontotemporal dementia and bipolar, cyclothymic mood disorder as clinical conditions that are helping to unravel the underlying neuroanatomy and neurochemistry of human creativity. This article is part of a Special Issue entitled "Epilepsy, Art, and Creativity". Copyright © 2016 Elsevier Inc. All rights reserved.

Exposing unethical human research: the transatlantic correspondence of Beecher and Pappworth.

PubMed

Gaw, Allan

2012-01-17

Henry K. Beecher and Maurice H. Pappworth were the 2 most prominent medical whistleblowers in research ethics of the 20th century. Independently, both wrote highly controversial and ultimately influential articles and books. Although their work is now well-known in clinical research circles, their collaboration is not. Pappworth's article "Human Guinea Pigs: A Warning" was published in 1962; in it, he discussed a series of published studies that he considered unethical. Beecher read it and wrote to Pappworth seeking help. The current article reconstructs, from Beecher and Pappworth's correspondence in 1965-1966, an important juncture in the genesis of modern clinical research ethics. Although they shared much in common, they differed radically in the strategies they adopted: Beecher chose to conceal the identities of individuals, whereas Pappworth believed that only by naming and shaming could any exposé act as a deterrent. Their correspondence reveals how the 2 men shared their ideas and their material and provided each other with much-needed support. It also tracks the development of Beecher's shift from a position initially indistinguishable from Pappworth's toward the one he adopted when his seminal article of 1966 was published.

Crew resource management in the ICU: the need for culture change

PubMed Central

2012-01-01

Intensive care frequently results in unintentional harm to patients and statistics don’t seem to improve. The ICU environment is especially unforgiving for mistakes due to the multidisciplinary, time-critical nature of care and vulnerability of the patients. Human factors account for the majority of adverse events and a sound safety climate is therefore essential. This article reviews the existing literature on aviation-derived training called Crew Resource Management (CRM) and discusses its application in critical care medicine. CRM focuses on teamwork, threat and error management and blame free discussion of human mistakes. Though evidence is still scarce, the authors consider CRM to be a promising tool for culture change in the ICU setting, if supported by leadership and well-designed follow-up. PMID:22913855

Recollecting, recognizing, and other acts of remembering: an overview of human memory.

PubMed

LaVoie, Donna J; Cobia, Derin J

2007-09-01

The question of whether memory is important to human existence is simple to answer: life without memory would be devoid of any meaning. The question of what memory is, however, is much more difficult to answer. The main purpose of this article is to provide an overview of memory function, by drawing distinctions between different memory systems, specifically declarative (ie, conscious) versus nondeclarative (ie, nonconscious) memory systems. To distinguish between these larger systems and their various components, we include discussion of deficits in memory that occur as a consequence of brain injury and normative aging processes. Included in these descriptions is discussion of the neuroanatomical correlates of each memory component described to illustrate the importance of particular brain regions to different aspects of memory function.

Pharmacomicrobiomics: the impact of human microbiome variations on systems pharmacology and personalized therapeutics.

PubMed

ElRakaiby, Marwa; Dutilh, Bas E; Rizkallah, Mariam R; Boleij, Annemarie; Cole, Jason N; Aziz, Ramy K

2014-07-01

The Human Microbiome Project (HMP) is a global initiative undertaken to identify and characterize the collection of human-associated microorganisms at multiple anatomic sites (skin, mouth, nose, colon, vagina), and to determine how intra-individual and inter-individual alterations in the microbiome influence human health, immunity, and different disease states. In this review article, we summarize the key findings and applications of the HMP that may impact pharmacology and personalized therapeutics. We propose a microbiome cloud model, reflecting the temporal and spatial uncertainty of defining an individual's microbiome composition, with examples of how intra-individual variations (such as age and mode of delivery) shape the microbiome structure. Additionally, we discuss how this microbiome cloud concept explains the difficulty to define a core human microbiome and to classify individuals according to their biome types. Detailed examples are presented on microbiome changes related to colorectal cancer, antibiotic administration, and pharmacomicrobiomics, or drug-microbiome interactions, highlighting how an improved understanding of the human microbiome, and alterations thereof, may lead to the development of novel therapeutic agents, the modification of antibiotic policies and implementation, and improved health outcomes. Finally, the prospects of a collaborative computational microbiome research initiative in Africa are discussed.

Pharmacomicrobiomics: The Impact of Human Microbiome Variations on Systems Pharmacology and Personalized Therapeutics

PubMed Central

ElRakaiby, Marwa; Dutilh, Bas E.; Rizkallah, Mariam R.; Boleij, Annemarie; Cole, Jason N.

2014-01-01

Abstract The Human Microbiome Project (HMP) is a global initiative undertaken to identify and characterize the collection of human-associated microorganisms at multiple anatomic sites (skin, mouth, nose, colon, vagina), and to determine how intra-individual and inter-individual alterations in the microbiome influence human health, immunity, and different disease states. In this review article, we summarize the key findings and applications of the HMP that may impact pharmacology and personalized therapeutics. We propose a microbiome cloud model, reflecting the temporal and spatial uncertainty of defining an individual's microbiome composition, with examples of how intra-individual variations (such as age and mode of delivery) shape the microbiome structure. Additionally, we discuss how this microbiome cloud concept explains the difficulty to define a core human microbiome and to classify individuals according to their biome types. Detailed examples are presented on microbiome changes related to colorectal cancer, antibiotic administration, and pharmacomicrobiomics, or drug–microbiome interactions, highlighting how an improved understanding of the human microbiome, and alterations thereof, may lead to the development of novel therapeutic agents, the modification of antibiotic policies and implementation, and improved health outcomes. Finally, the prospects of a collaborative computational microbiome research initiative in Africa are discussed. PMID:24785449

A human economy: A ``third way'' for the future of young people in the Middle East and North Africa

NASA Astrophysics Data System (ADS)

Zaalouk, Malak

2014-06-01

This paper looks at the vulnerability of today's youth worldwide, with a particular focus on the Middle East and North Africa (MENA), where the proportion of citizens aged 12-24 is particularly high at one-third of the total population. Cursed with poor education and few work opportunities, the youth unemployment rate has risen to 50 per cent in this region. There is a consequent lack of participation at all levels, and a large number of youth are showing symptoms of low self-esteem, frustration, anger and unrest. After discussing the outcomes of years of an inhuman economic system on a global level, this article points to a more humane and empowering path. The author argues that, instead of continuing with profit-oriented capitalism or relying on the informal sector, the co-operative way represents a third alternative to existing economic sectors within the dominant contemporary economic system. The article analyses the many benefits of this path for the realisation of a humane economy. In so doing, it touches on issues of equity and social protection. Finally, the article outlines what needs to be done if this is to be a viable solution for a human economy. While giving many examples of successful co-operative enterprises worldwide, the author singles out the MENA region as one which could also benefit from the new trends outlined.

Implications of the behavioural immune system for social behaviour and human health in the modern world.

PubMed

Schaller, Mark; Murray, Damian R; Bangerter, Adrian

2015-05-26

The 'behavioural immune system' is composed of mechanisms that evolved as a means of facilitating behaviours that minimized infection risk and enhanced fitness. Recent empirical research on human populations suggests that these mechanisms have unique consequences for many aspects of human sociality--including sexual attitudes, gregariousness, xenophobia, conformity to majority opinion and conservative sociopolitical attitudes. Throughout much of human evolutionary history, these consequences may have had beneficial health implications; but health implications in modern human societies remain unclear. This article summarizes pertinent ways in which modern human societies are similar to and different from the ecologies within which the behavioural immune system evolved. By attending to these similarities and differences, we identify a set of plausible implications-both positive and negative-that the behavioural immune system may have on health outcomes in contemporary human contexts. We discuss both individual-level infection risk and population-level epidemiological outcomes. We also discuss a variety of additional implications, including compliance with public health policies, the adoption of novel therapeutic interventions and actual immunological functioning. Research on the behavioural immune system, and its implications in contemporary human societies, can provide unique insights into relationships between fitness, sociality and health. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

Systematic review of economic evaluations of vaccination programs in mainland China: Are they sufficient to inform decision making?

PubMed

Pan, Xiong-Fei; Griffiths, Ulla K; Pennington, Mark; Yu, Hongjie; Jit, Mark

2015-11-17

The purpose of the study was to systematically review economic evaluations of vaccine programs conducted in mainland China. We searched for economic evaluations of vaccination in China published prior to August 3, 2015 in eight English-language and three Chinese-language databases. Each article was appraised against the 19-item Consensus on Health Economic Criteria list (CHEC-list). We found 23 papers evaluating vaccines against hepatitis B (8 articles), Streptococcus pneumoniae (5 articles), human papillomavirus (3 articles), Japanese encephalitis (2 articles), rotavirus (2 articles), hepatitis A (1 article), Enterovirus 71 (1 article) and influenza (1 article). Studies conformed to a mean of 12 (range: 6-18) items in the CHEC-list criteria. Five of six Chinese-language articles conformed to fewer than half of the 19 criteria items. The main criteria that studies failed to conform to included: inappropriate measurement (20 articles) and valuation (18 articles) of treatment and/or vaccination costs, no discussion about distributional implications (18 articles), missing major health outcomes (14 articles), no discussion about generalizability to other contexts (14 articles), and inadequate sensitivity analysis (13 articles). In addition, ten studies did not include major cost components of vaccination programs, and nine did not report outcomes in terms of life years even in cases where QALYs or DALYs were calculated. Only 13 studies adopted a societal perspective for analysis. All studies concluded that the appraised vaccination programs were cost-effective except for one evaluation of universal 7-valent pneumococcal conjugate vaccine (PCV-7) in children. However, three of the five studies on PCV-7 showed poor overall quality, and the number of studies on vaccines other than hepatitis B vaccine and PCV-7 was limited. In conclusion, major methodological flaws and reporting problems exist in current economic evaluations of vaccination programs in China. Local guidelines for good practice and reporting, institutional mechanisms and education may help to improve the overall quality of these evaluations. Copyright © 2015 Elsevier Ltd. All rights reserved.

The Stuff of Legend, or Unpacking Cultural Baggage? Introducing First-Year English Literature and Humanities Students to Foundational Literary Texts

ERIC Educational Resources Information Center

Beyer, Charlotte

2013-01-01

This article explores teaching and learning perspectives in relation to a first-year English Literature module on foundational literary texts and considers the value of certain assessment modes. The essay discusses methodological and pedagogical questions and argues that the module provides a contextual platform from which first-year students are…

Brilliant breastfeeding!

PubMed

Hilton, Sioned

2014-10-01

The 9th lactation and breastfeeding symposium was hosted in Madrid, Spain in April 2014. This year the team also shared the information further afield, taking to Twitter to run live chats. This article reports on three discussions of interest to The Practising Midwife readers: what is regarded as 'normal' in terms of breastfeeding; human milk lipids and health outcomes; and considering the research into the lactating mammary gland.

The Australian Early Development Index: Reshaping Family-Child Relationships in Early Childhood Education

ERIC Educational Resources Information Center

Peers, Chris

2011-01-01

This article addresses the cultural significance of the Australian Early Development Index (AEDI) and discusses changes that the discourse of this instrument makes to the way in which the child is conceptualised. It analyses the technological function of the AEDI to examine how it makes the child a universal resource for human capital. The article…

Key concepts regarding the genetics of hypertension in humans.

PubMed

Williams, R R

1991-11-01

More and more, genetic research is being used to investigate the problem of hypertension, especially as hypertension appears to be a population-wide phenomenon. This article discusses such key concepts as phenotypic variation within the hypertensive subpopulation, the importance of a family history for hypertension in predicting hypertension, the development of hypertension in youth, environmental considerations (nature v nurture), and gene linkage.

The Intersection of Catholic Social Teaching, Internationalization, and Marriage and Family Therapy: Lessons from the Borderlands

ERIC Educational Resources Information Center

Estrada, Ana Ulloa

2011-01-01

This article explores the relevance and challenge of Catholic Social Teaching (CST) and internationalization to the Marriage and Family Therapy (MFT) program at the University of San Diego. These issues are discussed in the context of a graduate level course on human diversity that culminated in a 1-day cultural immersion and service learning trip…

Making Public the Private Life of Plants: The Contribution of Informal Learning Environments

ERIC Educational Resources Information Center

Sanders, Dawn L.

2007-01-01

Plants are essential to life on Earth and yet are often deemed invisible by the human populace. Botanic gardens are an under-researched educational context and, as such, have occupied a peripheral arena in biology education discussions. This article seeks to readdress this absence and present the case for a more sustained use of informal learning…

Forms of Participation and Semiotic Mediation in Board Games for Second Language Learning

ERIC Educational Resources Information Center

Luk, Jasmine C. M.

2013-01-01

This article discusses a study on how language use and language development can be promoted through engaging students in different participation roles in board games. Theoretically, the study is grounded in sociocultural perspectives of activity theory and the role of play as a form of human motivation. A group of Grade 4 primary students learning…

Quality Education for All Young People: Challenges, Trends and Priorities

ERIC Educational Resources Information Center

Kagia, Ruth

2005-01-01

The purpose of this article is twofold. The first is to introduce the theme: "Responding to the educational needs of the young to bring about globalization with a human face," which formed part of the discussions at the 47th session of the International Conference on Education, Geneva, Switzerland, 8-11 September 2004. The second is to provide a…

On Human Kinds and Role Models: A Critical Discussion about the African American Male Teacher

ERIC Educational Resources Information Center

Brown, Anthony L.

2012-01-01

This article explores the theoretical implications around positioning the Black male teacher as the central agent of social change for Black male students. In addressing such concerns, my intention is not to discourage efforts to recruit and retain more African American men as teachers, but to trouble the commonsense assumptions embedded in such…

No-boundary thinking in bioinformatics research

PubMed Central

2013-01-01

Currently there are definitions from many agencies and research societies defining “bioinformatics” as deriving knowledge from computational analysis of large volumes of biological and biomedical data. Should this be the bioinformatics research focus? We will discuss this issue in this review article. We would like to promote the idea of supporting human-infrastructure (HI) with no-boundary thinking (NT) in bioinformatics (HINT). PMID:24192339

"A Grammar for Black Education beyond Borders": Exploring Technologies of Schooling in the African Diaspora

ERIC Educational Resources Information Center

Givens, Jarvis Ray

2016-01-01

Education has been a technology used to sustain black abjection across the African Diaspora. Employing Mills' Racial Contract and Althusser's theory of the Ideological State Apparatuses (ISA) through a racial lens, this article will discuss how white supremacist education has been used to promote the misrecognition of black subjects as sub-human.…

Contemporary Issues Reader One: A Humanistic View of Diversity and Commonality in the Tribal and American Indian Community.

ERIC Educational Resources Information Center

Beck, David, Ed.

This volume is a collection of articles by American Indian educators, counselors, and administrators who seek to record the transformation of oral traditions into literate through the use of the written word. A variety of topics are discussed within broad frameworks, from the humanities to the highly technical. "Indian Learners and Public…

"La realidad mágica de Oaxaca--Colores, olores y sabores de Oaxaca": An Interactive Workshop for Spanish Teachers

ERIC Educational Resources Information Center

Centeno, Pamela; Wells, Christine

2004-01-01

As the fortunate participants in the National Endowment for the Humanities summer institute entitled La Realidad Mágica de Oaxaca, the authors designed interactive ways to share their rich and colorful learning experiences with their students and colleagues. This article discusses how the authors presented their Oaxacan adventures in an all-day…

20th-Century Humanism and 21st-Century Technology: A Match Made in Cyberspace

ERIC Educational Resources Information Center

Samuels, Harry

2013-01-01

This article discusses the origins of humanistic education beginning in the 1960s. The philosophy gained popularity among educators in a variety of disciplines and was adopted by teachers of foreign languages. That method was based on the premise that if students feel better about themselves, they will achieve greater results as learners.…

Volcano-ice age link discounted

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kerr, R.A.

1996-05-10

Speculation that huge volcanic eruptions may have caused an immediate `volcanic winter` that devastated early humans and accelerated a slide into the Ice Age. However, further information from the Greenland ice sheet about the Toba errumption on the island of Sumatra 70,000 years ago, seems to indicate that such volcanic actions wasn`t a major climatic catalyst. This article discusses the evidence and further possibilities.

Genus Tabanus. Tabanids (horseflies). What is this insect and how does it affect man?

PubMed

Strother, S

1999-11-01

The insect family Tabanidae (Order: Diptera) comprises approximately 3000 species of flies worldwide, including the commonly known horseflies and deerflies. Females of most species require a blood meal to complete egg development and many species are important in human and animal medicine. This article briefly discusses the life cycle, biology, and medical significance of tabanids.

"I Am a Human Being like You": An Identification Strategy to Maintain Continuity in a Cultural Contact Zone

ERIC Educational Resources Information Center

O'Sullivan-Lago, Ria; de Abreu, Guida; Burgess, Mark

2008-01-01

In this article, we discuss a qualitative study carried out in a cultural contact zone. Irish nationals, immigrants, and asylum seekers in Cork, Ireland, were interviewed about their cultural identities and future trajectories. Cultural Continuity theory was used as a model to offer an insight into the processes and strategies of the Dialogical…

Universal precautions: an update.

PubMed

Gershon, R R; Karkashian, C; Felknor, S

1994-01-01

Universal precautions, the set of work practice recommendations designed to help minimize occupational exposure to bloodborne pathogens, have been shown to be effective. However, lack of compliance with these recommendations has been well documented, both before and after the enactment of the OSHA Bloodborne Pathogens Standard. Current issues, including occupationally acquired human immunodeficiency virus, percutaneous exposures and lack of compliance are discussed in this article.

Fairy Castle or Steamer Trunk? Creating Place in O. E. Rolvaag's "Giants in the Earth"

ERIC Educational Resources Information Center

Quantic, Diane

2003-01-01

Rolvaag's story is grounded in the relationship between the undifferentiated environment and the built environment--that is, the structures that anchor people in place and define the parameters of human existence where geographical landmarks are few. This article is a discussion of the ways Rolvaag elicits this process in both the land and the…

SoTL and the Institutional Review Board: Considerations before Navigating the Application Process for Classroom Research in Higher Education

ERIC Educational Resources Information Center

Linder, Kathryn E.; Elek, E. Deborah; Calderon, Lucia

2014-01-01

One of the more challenging areas of "Scholarship of Teaching and Learning" (SoTL) research can be navigating the components of human subjects research protections implemented by the Institutional Review Board (IRB). The authors of this article, a faculty developer and a current and former research compliance coordinator, discuss the…

Public and Professional Constructions of Mental Retardation: Glen Ridge and the Missing Narrative of Disability Rights.

ERIC Educational Resources Information Center

Biklen, Douglas; Schein, Philip Lambert

2001-01-01

This article discusses a court case of an adolescent labeled retarded who was sexually assaulted. It examines implications of being spoken about and of others speaking for the labeled person. It then considers how a disability rights/People First framework could shift public and professional understandings and responses to human abuse. (Contains…

Water Delivery--It's All about Pressure

ERIC Educational Resources Information Center

Roman, Harry T.

2005-01-01

There is a great deal of wisdom in the old saying "water seeks its level." In fact, the concept has bearing on a very practical side of human life as well, since the public water delivery system is based on it. In this article, the author discusses the concept behind water pressure and describes how the water systems work based on this concept.…

Humanizing the Teaching of Physics through Storytelling: The Case of Current Electricity

ERIC Educational Resources Information Center

Hadzigeorgiou, Yannis

2006-01-01

The main purpose of this article is to discuss the potential role of storytelling in the teaching and learning of physics. I first present the main historical events concerning the discovery of current electricity by focusing on the Galvani-Volta controversy and the work of Michael Faraday. Then I outline a planning framework for teaching through…

Aquinas's account of human embryogenesis and recent interpretations.

PubMed

Eberl, Jason T

2005-08-01

In addressing bioethical issues at the beginning of human life, such as abortion, in vitro fertilization, and embryonic stem cell research, one primary concern regards establishing when a developing human embryo or fetus can be considered a person. Thomas Aquinas argues that an embryo or fetus is not a human person until its body is informed by a rational soul. Aquinas's explicit account of human embryogenesis has been generally rejected by contemporary scholars due to its dependence upon medieval biological data, which has been far surpassed by current scientific research. A number of scholars, however, have attempted to combine Aquinas's basic metaphysical account of human nature with current embryological data to develop a contemporary Thomistic account of a human person's beginning. In this article, I discuss two recent interpretations in which it is argued that a human person does not begin to exist until a fetus has developed a functioning cerebral cortex.

Midwives and human rights: dream or reality?

PubMed

Thompson, Joyce E

2002-09-01

Midwives as predominantly women caring for other women are subject to the same human rights violations and abuse that affect all the women of the world. They need to know and recognise these human rights violations before being able to take action that will reduce or eliminate such harmful practices. In this article, I address gender-based violations of the basic human rights of particular concern to women during their childbearing years, such as personal safety, respect for human dignity, fair and equitable access to health services, along with autonomous decision-making based on complete and unbiased information. The ethical and legal foundations of human rights are discussed in relation to viewing women as fully human, fully persons. Guidance for midwives taken from key documents of the International Confederation of Midwives are offered as midwives work together with women to end gender-based violations of one's human rights.

Characterization of potential endocrine-related health effects at low-dose levels of exposure to PCBs.

PubMed Central

Brouwer, A; Longnecker, M P; Birnbaum, L S; Cogliano, J; Kostyniak, P; Moore, J; Schantz, S; Winneke, G

1999-01-01

This article addresses issues related to the characterization of endocrine-related health effects resulting from low-level exposures to polychlorinated biphenyls (PCBs). It is not intended to be a comprehensive review of the literature but reflects workshop discussions. "The Characterizing the Effects of Endocrine Disruptors on Human Health at Environmental Exposure Levels," workshop provided a forum to discuss the methods and data needed to improve risk assessments of endocrine disruptors. This article contains an overview of endocrine-related (estrogen and thyroid system) interactions and other low-dose effects of PCBs. The data set on endocrine effects includes results obtained from mechanistic methods/ and models (receptor based, metabolism based, and transport protein based), as well as from (italic)in vivo(/italic) models, including studies with experimental animals and wildlife species. Other low-dose effects induced by PCBs, such as neurodevelopmental and reproductive effects and endocrine-sensitive tumors, have been evaluated with respect to a possible causative linkage with PCB-induced alterations in endocrine systems. In addition, studies of low-dose exposure and effects in human populations are presented and critically evaluated. A list of conclusions and recommendations is included. PMID:10421775

Robotic automation of medication-use management.

PubMed

Enright, S M

1993-11-01

In the October 1993 issue of Physician Assistant, we published "Robots for Health Care," the first of two articles on the medical applications of robotics. That article discussed ways in which robots could help patients with manipulative disabilities to perform activities of daily living and hold paid employment; transfer patients from bed to chair and back again; add precision to the most exacting surgical procedures; and someday carry out diagnostic and therapeutic techniques from within the human body. This month, we are pleased to offer an article by Sharon Enright, an authority on pharmacy operations, who considers how an automated medication-management system that makes use of bar-code technology is capable of streamlining drug dispensing, controlling safety, increasing cost-effectiveness, and ensuring accurate and complete record-keeping.

Izabel dos Santos and the training of the health workers.

PubMed

Paiva, Carlos Henrique Assunção

2015-06-01

This article discusses the career of Izabel dos Santos (1927-2010) as a means of examining the connections between health schools and agendas in contemporary Brazil. The article highlights dos Santos's training and her work in the Serviço Especial de Saúde Pública (SESP- Special Public Health Service), the Pan American Health Organization (PAHO) and in the formulation and implementation of national training programs for human resources within the area of health from the late 1970s onwards. The article highlights dos Santos's central role in the formulation and implementation of training policies for health workers, especially nursing technicians and assistants, and demonstrates how she occupies an important place in the history of Brazilian public health.

Is inclusive education a human right?

PubMed

Gordon, John-Stewart

2013-01-01

In this article, I question the general idea that inclusive education--i.e., to teach all students in one class--is a moral human right. The following discussion shows that the widespread view in disability studies that there is a moral human right to inclusive education can be reasonably called into question by virtue of the proposed counter arguments, but without denying that inclusive education is of utmost importance. Practically speaking, the legal human right to inclusive education is of great practical value for impaired students, and for their basic right to be free from discrimination in education, since their concern thereby gains great legal and moral force. But, theoretically speaking, this particular human right lacks an attainable consensus concerning proper moral justification. © 2013 American Society of Law, Medicine & Ethics, Inc.

The ethics of patenting human embryonic stem cells.

PubMed

Chapman, Audrey R

2009-09-01

Just as human embryonic stem cell research has generated controversy about the uses of human embryos for research and therapeutic applications, human embryonic stem cell patents raise fundamental ethical issues. The United States Patent and Trademark Office has granted foundational patents, including a composition of matter (or product) patent to the Wisconsin Alumni Research Foundation (WARF), the University of Wisconsin-Madison's intellectual property office. In contrast, the European Patent Office rejected the same WARF patent application for ethical reasons. This article assesses the appropriateness of these patents placing the discussion in the context of the deontological and consequentialist ethical issues related to human embryonic stem cell patenting. It advocates for a patent system that explicitly takes ethical factors into account and explores options for new types of intellectual property arrangements consistent with ethical concerns.

[Attitude toward sexual life of young adult medical and nursing students].

PubMed

Mroczek, Bozena; Karakiewicz, Beata

2004-01-01

Nowadays can observe not only changes of views on human sexuality but also of its nomenclature. These changes also apply to the issues related to human sexuality which plays an role in psychological purposes. The article discusses psychological and pedagogical aspects of human sexuality on the threshold of adult life. 83 students of post-GCSE faculties of the medical school were interviewed. The aim of the study was to determine the attitude towards sexual life expressed by young people entering their adult life. The study tool was a questionnaire technique. Results were statistically analyzed. The results showed that: the level of knowledge of sexual life is low among adults: lack of correlation between emotional and cognitive elements of attitudes towards human sexuality; sexual behaviours depend on human sex.

Neo-Symbiosis: The Next Stage in the Evolution of Human Information Interaction.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Griffith, Douglas; Greitzer, Frank L.

In his 1960 paper Man-Machine Symbiosis, Licklider predicted that human brains and computing machines will be coupled in a tight partnership that will think as no human brain has ever thought and process data in a way not approached by the information-handling machines we know today. Today we are on the threshold of resurrecting the vision of symbiosis. While Licklider’s original vision suggested a co-equal relationship, here we discuss an updated vision, neo-symbiosis, in which the human holds a superordinate position in an intelligent human-computer collaborative environment. This paper was originally published as a journal article and is being publishedmore » as a chapter in an upcoming book series, Advances in Novel Approaches in Cognitive Informatics and Natural Intelligence.« less

THE RIGHT TO SUTURES: SOCIAL EPIDEMIOLOGY, HUMAN RIGHTS, AND SOCIAL JUSTICE

PubMed Central

Venkatapuram, Sridhar; Bell, Ruth; Marmot, Michael

2013-01-01

The article examines the convergences and contrasts between social epidemiology, social medicine, and human rights approaches toward advancing global health and health equity. The first section describes the goals and work of the WHO Commission on Social Determinants of Health. The second section discusses the role of human rights in the Commission’s work. The third section evaluates, from the perspective of social epidemiology, two rights-based approaches to advancing health and health equity as compared to a view that focuses more broadly on social justice. The concluding section identifies four areas where social epidemiologists, practitioners of social medicine, and health and human rights advocates can and must work together in order to make progress on health and health equity. PMID:21178186

Human trafficking law and social structures.

PubMed

Wooditch, Alese

2012-08-01

Human trafficking has only recently emerged at the forefront of policy reform, even in developed nations. Yet, heightened awareness of the issue has not translated into effective policy as the majority of nations have ineffective antitrafficking practices; many countries have failed to criminalize human trafficking, whereas others do not actively enforce statutes in place. By applying Black's theory of law, this study offers a preliminary understanding into the variation of global prosecutorial efforts in human trafficking and adequacy of antitrafficking law. To isolate this relationship, the effects of trafficking markets are controlled. As with prior research, the study finds limited support for the theory. The article concludes with a discussion on the implications of the quantity of antitrafficking law and morphology association for policy development.

The renewal of humanism in psychotherapy: summary and conclusion.

PubMed

Schneider, Kirk J; Längle, Alfried

2012-12-01

This article summarizes and discusses the main themes to emerge from this special section on the renewal of humanism in psychotherapy. It is concluded that (1) despite some controversies, humanism is both a viable and growing influence among the leading specialty areas of psychotherapy; (2) humanism is a foundational element of effectiveness among these specialty areas; and (3) humanistic training is essential to the development of trainees in the aforementioned specialty areas. The implications of these findings for each of the specialty areas, for the profession of psychotherapy, and for the public at large are elaborated, concluding with a call for a reassessment of priorities in the research, practice, and training of standardized mental health delivery. (c) 2012 APA, all rights reserved.

Advancing rights for women: the role of litigation.

PubMed

Cabal, Luisa

2006-12-01

Litigation is becoming an increasingly attractive advocacy tool for human rights movements around the world. It has served as an effective strategy not only for reforming or enforcing laws that deny or protect basic human rights, but also for raising awareness of and mobilizing support for human rights issues. In this article, which is based on a presentation at a symposium session at the conference, Luisa Cabal focuses on a specific area within the realm of women's health and rights--the rights of HIV-positive women and girls, and in particular, violations they experience vis-à-vis access to health care--and discusses the potential for litigation to help raise awareness and advance efforts to protect and promote human rights in this area.

[Nutritional epigenetics and epigenetic effects of human breast milk].

PubMed

Lukoyanova, O L; Borovik, T E

The article provides an overview of the current literature on nutritional epigenetics. There are currently actively studied hypothesis that nutrition especially in early life or in critical periods of the development, may have a role in modulating gene expression, and, therefore, have later effects on health in adults. Nutritional epigenetics concerns knowledge about the possible effects of nutrients on gene expression. Human breast milk is well-known for its ability in preventing necrotizing enterocolitis, infectious diseases, and also non-communicable diseases, such as obesity and related disorders. This paper discusses about presumed epigenetic effects of human breast milk and some its components. While evidence suggests that a direct relationship may exist of some components of human breast milk with epigenetic changes, the mechanisms involved are stillunclear.

Some Non-FDA Approved Uses for Neuromodulation in Treating Autonomic Nervous System Disorders: A Discussion of the Preliminary Support.

PubMed

Lee, Samuel; Abd-Elsayed, Alaa

2016-12-01

Neuromodulation, including cavernous nerve stimulation, gastric electrical stimulation, deep brain stimulation, and vagus nerve stimulation, has been used with success in treating several functional disease conditions. The FDA has approved the use of neuromodulation for a few indications. We discuss in our review article the evidence of using neuromodulation for treating some important disorders involving the autonomic nervous system that are not currently FDA approved. This was a review article that included a systematic online web search for human clinical studies testing the efficacy of neuromodulation in treating erectile dysfunction, gastroparesis, gastroesophageal reflux disease, obesity, asthma, and heart failure. Our review includes all feasibility studies, nonrandomized clinical trials, and randomized controlled trials. Our systematic literature search found 3, 4, 5, 4, 1, and 4 clinical studies relating to erectile dysfunction, gastroparesis, gastroesophageal reflux disease, obesity, asthma, and heart failure, respectively. This review article shows preliminary support based on clinical studies that neuromodulation can be of benefit for patients with important autonomic nervous system disease conditions that are not currently approved by the FDA. All of these investigational uses are encouraging; further studies are necessary and warranted for all indications discussed in this review before achieving FDA approval. © 2016 International Neuromodulation Society.

[The beginning of human life: ethical and legal perspectives in the context of biotechnological progress].

PubMed

Barretto, Vicente de Paulo; Lauxen, Elis Cristina Uhry

2017-07-13

Questions concerning the beginning of human life have pervaded society since antiquity. In the post-modern world, scientific and technological advances have fueled discussions on the issue, such that debates previously concentrated on abortion now also focus on biotechnological interventions. The article addresses the latter, reflecting on the extent to which human dignity can be considered a (hermeneutic) reference in establishing ethical and legal parameters for biotechnological advances in the definition of the beginning of human life. The study's method was critical hermeneutic ethics, with ethics at the center of the process of understanding and interpretation, observing the contours of facticity. No consensus was found on the beginning of human life, so it is essential to engage in dialogue with the new reality resulting from biotechnological advances in the process of defining ethical and legal principles for protecting the embryo and human nature, with human dignity as the reference.

Building a human rights framework for workers' compensation in the United States: opening the debate on first principles.

PubMed

Hilgert, Jeffrey A

2012-06-01

This article introduces the idea of human rights to the topic of workers' compensation in the United States. It discusses what constitutes a human rights approach and explains how this approach conflicts with those policy ideas that have provided the foundation historically for workers' compensation in the United States. Using legal and historical research, key international labor and human rights standards on employment injury benefits and influential writings in the development of the U.S. workers' compensation system are cited. Workers' injury and illness compensation in the United States does not conform to basic international human rights norms. A comprehensive review of the U.S. workers' compensation system under international human rights standards is needed. Examples of policy changes are highlighted that would begin the process of moving workers' compensation into conformity with human rights standards. Copyright © 2012 Wiley Periodicals, Inc.

Human space exploration the next fifty years.

PubMed

Williams, David R; Turnock, Matthew

2011-06-01

Preparation for the fiftieth anniversary of human spaceflight in the spring of 2011 provides the space faring nations with an opportunity to reflect on past achievements as well as consider the next fifty years of human spaceflight. The International Space Station is a unique platform for long duration life science research that will play a critical role in preparing for future human space exploration beyond low earth orbit. Some feel the future path back to the Moon and on to Mars may be delayed with the current commitment of the United States to support the development of human-rated commercial spacecraft. Others see this as a unique opportunity to leverage the capability of the private sector in expanding access to space exploration. This article provides an overview of the past achievements in human spaceflight and discusses future missions over the next fifty years and the role space medicine will play in extending the time-distance constant of human space exploration.

Neuropeptidomics Mass Spectrometry Reveals Signaling Networks Generated by Distinct Protease Pathways in Human Systems

NASA Astrophysics Data System (ADS)

Hook, Vivian; Bandeira, Nuno

2015-12-01

Neuropeptides regulate intercellular signaling as neurotransmitters of the central and peripheral nervous systems, and as peptide hormones in the endocrine system. Diverse neuropeptides of distinct primary sequences of various lengths, often with post-translational modifications, coordinate and integrate regulation of physiological functions. Mass spectrometry-based analysis of the diverse neuropeptide structures in neuropeptidomics research is necessary to define the full complement of neuropeptide signaling molecules. Human neuropeptidomics has notable importance in defining normal and dysfunctional neuropeptide signaling in human health and disease. Neuropeptidomics has great potential for expansion in translational research opportunities for defining neuropeptide mechanisms of human diseases, providing novel neuropeptide drug targets for drug discovery, and monitoring neuropeptides as biomarkers of drug responses. In consideration of the high impact of human neuropeptidomics for health, an observed gap in this discipline is the few published articles in human neuropeptidomics compared with, for example, human proteomics and related mass spectrometry disciplines. Focus on human neuropeptidomics will advance new knowledge of the complex neuropeptide signaling networks participating in the fine control of neuroendocrine systems. This commentary review article discusses several human neuropeptidomics accomplishments that illustrate the rapidly expanding diversity of neuropeptides generated by protease processing of pro-neuropeptide precursors occurring within the secretory vesicle proteome. Of particular interest is the finding that human-specific cathepsin V participates in producing enkephalin and likely other neuropeptides, indicating unique proteolytic mechanisms for generating human neuropeptides. The field of human neuropeptidomics has great promise to solve new mechanisms in disease conditions, leading to new drug targets and therapeutic agents for human diseases.

Modulation of the Gastrointestinal Microbiome with Nondigestible Fermentable Carbohydrates To Improve Human Health.

PubMed

Deehan, Edward C; Duar, Rebbeca M; Armet, Anissa M; Perez-Muñoz, Maria Elisa; Jin, Mingliang; Walter, Jens

2017-09-01

There is a clear association between the gastrointestinal (GI) microbiome and the development of chronic noncommunicable diseases, providing a rationale for the development of strategies that target the GI microbiota to improve human health. In this article, we discuss the potential of supplementing the human diet with nondigestible fermentable carbohydrates (NDFCs) to modulate the composition, structure, diversity, and metabolic potential of the GI microbiome in an attempt to prevent or treat human disease. The current concepts by which NDFCs can be administered to humans, including prebiotics, fermentable dietary fibers, and microbiota-accessible carbohydrates, as well as the mechanisms by which these carbohydrates exert their health benefits, are discussed. Epidemiological research presents compelling evidence for the health effects of NDFCs, with clinical studies providing further support for some of these benefits. However, rigorously designed human intervention studies with well-established clinical markers and microbial endpoints are still essential to establish (i) the clinical efficiency of specific NDFCs, (ii) the causal role of the GI microbiota in these effects, (iii) the underlying mechanisms involved, and (iv) the degree by which inter-individual differences between GI microbiomes influence these effects. Such studies would provide the mechanistic understanding needed for a systematic application of NDFCs to improve human health via GI microbiota modulation while also allowing the personalization of these dietary strategies.

Insuring the unknown.

PubMed

Parsons, C

2015-12-01

Uncertainty is the central element in insurance. This article examines how insurers evaluate and price risks that can present very high levels of uncertainty, and which many underwriters regard as especially hazardous in insurance terms. These are the risks associated with new medical devices, new pharmaceutical products and others substances for human consumption, such as food additives. Insurance is likely to be needed for these products both during their research and development phases, including insurance for clinical trials, and also once the device, drug or other substance gains approval and is in regular use.The article examines the types of insurance that are available to cover these risks, the organizations that provide insurance and how the insurance is organised. It discusses the basic principles that insurers use to price insurance before considering the difficulties presented by novel and complex risks generally. The article concludes with a description of the techniques that insurers employ to analyse and price the particular risks that are our subject and a discussion of how underwriters seek to overcome the special problems associated with them. © The Author(s) 2015.

The commodification of the body and its parts.

PubMed

Sharp, L A

2000-01-01

The human body--and its parts--has long been a target for commodification within myriad cultural settings. A discussion of commodification requires that one consider, first, the significance of the body within anthropology and, second, what defines a body "part." After exploring these initial questions, this article outlines dominant theoretical approaches to commodification within anthropology, with Mauss and Marx figuring prominently. The discussion then turns to historically well-documented forms of body commodification: These include slavery and other oppressive labor practices; female reproduction; and the realms of sorcery and endocannibalism. An analysis here uncovers dominant established approaches that continue to drive current studies. The remainder of this article concerns emergent biotechnologies, whose application in clinical and other related scientific arenas marks a paradigmatic shift in anthropological understandings of the commodified, fragmented body. The following contexts are explored with care: reproductive technologies; organ transplantation; cosmetic and transsexual surgeries; genetics and immunology; and, finally, the category of the cyborg. The article concludes with suggestions for an integrated theoretical vision, advocating greater cross-fertilization of analytical approaches and the inclusion of an ethics of body commodification within anthropology.

Dental radiographic indicators, a key to age estimation

PubMed Central

Panchbhai, AS

2011-01-01

Objective The present review article is aimed at describing the radiological methods utilized for human age identification. Methods The application and importance of radiological methods in human age assessment was discussed through the literature survey. Results Following a literature search, 46 articles were included in the study and the relevant information is depicted in the article. Dental tissue is often preserved indefinitely after death. Implementation of radiography is based on the assessment of the extent of calcification of teeth and in turn the degree of formation of crown and root structures, along with the sequence and the stages of eruption. Several radiological techniques can be used to assist in both individual and general identification, including determination of gender, ethnic group and age. The radiographic method is a simpler and cheaper method of age identification compared with histological and biochemical methods. Radiographic and tomographic images have become an essential aid for human identification in forensic dentistry, particularly with the refinement of techniques and the incorporation of information technology resources. Conclusion Based on an appropriate knowledge of the available methods, forensic dentists can choose the most appropriate since the validity of age estimation crucially depends on the method used and its proper application. The multifactorial approach will lead to optimum age assessment. The legal requirements also have to be considered. PMID:21493876

Connectome imaging for mapping human brain pathways

PubMed Central

Shi, Y; Toga, A W

2017-01-01

With the fast advance of connectome imaging techniques, we have the opportunity of mapping the human brain pathways in vivo at unprecedented resolution. In this article we review the current developments of diffusion magnetic resonance imaging (MRI) for the reconstruction of anatomical pathways in connectome studies. We first introduce the background of diffusion MRI with an emphasis on the technical advances and challenges in state-of-the-art multi-shell acquisition schemes used in the Human Connectome Project. Characterization of the microstructural environment in the human brain is discussed from the tensor model to the general fiber orientation distribution (FOD) models that can resolve crossing fibers in each voxel of the image. Using FOD-based tractography, we describe novel methods for fiber bundle reconstruction and graph-based connectivity analysis. Building upon these novel developments, there have already been successful applications of connectome imaging techniques in reconstructing challenging brain pathways. Examples including retinofugal and brainstem pathways will be reviewed. Finally, we discuss future directions in connectome imaging and its interaction with other aspects of brain imaging research. PMID:28461700

Human Error: A Concept Analysis

NASA Technical Reports Server (NTRS)

Hansen, Frederick D.

2007-01-01

Human error is the subject of research in almost every industry and profession of our times. This term is part of our daily language and intuitively understood by most people however, it would be premature to assume that everyone's understanding of human error s the same. For example, human error is used to describe the outcome or consequence of human action, the causal factor of an accident, deliberate violations,a nd the actual action taken by a human being. As a result, researchers rarely agree on the either a specific definition or how to prevent human error. The purpose of this article is to explore the specific concept of human error using Concept Analysis as described by Walker and Avant (1995). The concept of human error is examined as currently used in the literature of a variety of industries and professions. Defining attributes and examples of model, borderline, and contrary cases are described. The antecedents and consequences of human error are also discussed and a definition of human error is offered.

Are South African Speech-Language Therapists adequately equipped to assess English Additional Language (EAL) speakers who are from an indigenous linguistic and cultural background? A profile and exploration of the current situation

PubMed Central

Mdlalo, Thandeka; Flack, Penelope

2016-01-01

This article presents the results of a survey conducted on Speech-Language Therapists (SLTs) regarding current practices in the assessment of English Additional Language (EAL) speakers in South Africa. It forms part of the rationale for a broader (PhD) study that critiques the use of assessment instruments on EAL speakers from an indigenous linguistic and cultural background. This article discusses an aspect of the broader research and presents the background, method, findings, discussion and implications of the survey. The results of this survey highlight the challenges of human and material resources to, and the dominance of English in, the profession in South Africa. The findings contribute to understanding critical factors for acquiring reliable and valid assessment results with diverse populations, particularly the implications from a cultural and linguistic perspective. PMID:27247254

The most important of all the organs: Darwin on the brain.

PubMed

Jacyna, Stephen

2009-12-01

This article discusses Charles Darwin's interest in topics that may broadly be defined as 'neurological' in character. Using published and manuscript materials, it examines the sources of Darwin's knowledge of neurological matters and seeks to explain why questions concerning the relation of mind and brain both in humans and other animals were relevant to his wider concerns. The paper concludes with a discussion of Darwin's impact on late 19th and early 20th century neurological thought. The 150th anniversary of the publication of the Origin of Species and the 200th of the birth of its author afford an opportunity to reflect on Charles Darwin's relationship to neurology. The first section of this article considers the part played by what might broadly be defined as 'neurological' materials in the shaping of Darwin's theory. The following section provides a brief review of the impact that Darwin's ideas were to have upon subsequent neurological thought.

A conceptual model of transference and its psychotherapeutic application.

PubMed

Corradi, Richard B

2006-01-01

The tendency to repeat formative human relationships in later life, a universal developmental characteristic, is referred to as transference when it occurs in the doctor-patient relationship. Its systematic therapeutic application in psychiatry has historically been associated with classical psychoanalysis. As psychoanalysis has lost its cachet, and as drug treatment has replaced psychotherapy as psychiatry's major treatment modality, the therapeutic potential of transference risks being neglected. This is to the great detriment of psychiatric patients. Knowledge of the power of transference and expertise in its clinical use in psychotherapy should be the most powerful tool in the psychiatric therapeutic armamentarium. This article discusses a concept of transference that the author has found effective, both in clinical practice and in teaching about transference to psychiatric residents. The article delineates a psychology of transference, discusses its universal applicability to the whole of the psychotherapeutic process, and utilizes case material to illustrate principles of its application.

Bioinformatics: perspectives for the future.

PubMed

Costa, Luciano da Fontoura

2004-12-30

I give here a very personal perspective of Bioinformatics and its future, starting by discussing the origin of the term (and area) of bioinformatics and proceeding by trying to foresee the development of related issues, including pattern recognition/data mining, the need to reintegrate biology, the potential of complex networks as a powerful and flexible framework for bioinformatics and the interplay between bio- and neuroinformatics. Human resource formation and market perspective are also addressed. Given the complexity and vastness of these issues and concepts, as well as the limited size of a scientific article and finite patience of the reader, these perspectives are surely incomplete and biased. However, it is expected that some of the questions and trends that are identified will motivate discussions during the IcoBiCoBi round table (with the same name as this article) and perhaps provide a more ample perspective among the participants of that conference and the readers of this text.

Persistent estrus rat models of polycystic ovary disease: an update.

PubMed

Singh, Krishna B

2005-10-01

To critically review published articles on polycystic ovary (PCO) disease in rat models, with a focus on delineating its pathophysiology. Review of the English-language literature published from 1966 to March 2005 was performed through PubMed search. Keywords or phrases used were persistent estrus, chronic anovulation, polycystic ovary, polycystic ovary disease, and polycystic ovary syndrome. Articles were also located via bibliographies of published literature. University Health Sciences Center. Articles on persistent estrus and PCO in rats were selected and reviewed regarding the methods for induction of PCO disease. Changes in the reproductive cycle, ovarian morphology, hormonal parameters, and factors associated with the development of PCO disease in rat models were analyzed. Principal methods for inducing PCO in the rat include exposure to constant light, anterior hypothalamic and amygdaloidal lesions, and the use of androgens, estrogens, antiprogestin, and mifepristone. The validated rat PCO models provide useful information on morphologic and hormonal disturbances in the pathogenesis of chronic anovulation in this condition. These studies have aimed to replicate the morphologic and hormonal characteristics observed in the human PCO syndrome. The implications of these studies to human condition are discussed.

[Neurobiology of learning and memory and anti-dementia drug].

PubMed

Ishikawa, K

1995-08-01

Discoveries of long-term potentiation and immediate early gene in the central nervous system have enabled new developments in experiments on learning and memory. These experiments are conducted in many kinds of animals with different procedures, physiology, chemistry and pharmacology. However, there is still some confusion when these various procedures are discussed. Memory is defined as information storage of an animal's previous experiences. The memory induces changes in behavioral performance. This means that memory must be observed in whole animals, and one question that can occur is how does long-term potentiation, for example, correlate with memory. Furthermore, memory has been divided into two major classifications, declarative and non-declarative, from the comparison of amnesias observed in humans and animals. The declarative memory can be observed in human subjects, but not in animals. This article presents a neuronal circuit concerning memory formation and some results obtained from benzodiazepines, and it discusses some problems encountered executing when experiments on learning and memory. In addition, the discussion speculates over the possibility for an "anti-dementia drug".

Controlling uncertainty: a review of human behavior in complex dynamic environments.

PubMed

Osman, Magda

2010-01-01

Complex dynamic control (CDC) tasks are a type of problem-solving environment used for examining many cognitive activities (e.g., attention, control, decision making, hypothesis testing, implicit learning, memory, monitoring, planning, and problem solving). Because of their popularity, there have been many findings from diverse domains of research (economics, engineering, ergonomics, human-computer interaction, management, psychology), but they remain largely disconnected from each other. The objective of this article is to review theoretical developments and empirical work on CDC tasks, and to introduce a novel framework (monitoring and control framework) as a tool for integrating theory and findings. The main thesis of the monitoring and control framework is that CDC tasks are characteristically uncertain environments, and subjective judgments of uncertainty guide the way in which monitoring and control behaviors attempt to reduce it. The article concludes by discussing new insights into continuing debates and future directions for research on CDC tasks.

Emotional responses to interpersonal rejection

PubMed Central

Leary, Mark R.

2015-01-01

A great deal of human emotion arises in response to real, anticipated, remembered, or imagined rejection by other people. Because acceptance by other people improved evolutionary fitness, human beings developed biopsychological mechanisms to apprise them of threats to acceptance and belonging, along with emotional systems to deal with threats to acceptance. This article examines seven emotions that often arise when people perceive that their relational value to other people is low or in potential jeopardy, including hurt feelings, jealousy, loneliness, shame, guilt, social anxiety, and embarrassment. Other emotions, such as sadness and anger, may occur during rejection episodes, but are reactions to features of the situation other than low relational value. The article discusses the evolutionary functions of rejection-related emotions, neuroscience evidence regarding the brain regions that mediate reactions to rejection, and behavioral research from social, developmental, and clinical psychology regarding psychological and behavioral concomitants of interpersonal rejection. PMID:26869844

Regenerative medicine in otorhinolaryngology.

PubMed

Wormald, J C R; Fishman, J M; Juniat, S; Tolley, N; Birchall, M A

2015-08-01

Tissue engineering using biocompatible scaffolds, with or without cells, can permit surgeons to restore structure and function following tissue resection or in cases of congenital abnormality. Tracheal regeneration has emerged as a spearhead application of these technologies, whilst regenerative therapies are now being developed to treat most other diseases within otolaryngology. A systematic review of the literature was performed using Ovid Medline and Ovid Embase, from database inception to 15 November 2014. A total of 561 papers matched the search criteria, with 76 fulfilling inclusion criteria. Articles were predominantly pre-clinical animal studies, reflecting the current status of research in this field. Several key human research articles were identified and discussed. The main issues facing research in regenerative surgery are translation of animal model work into human models, increasing stem cell availability so it can be used to further research, and development of better facilities to enable implementation of these advances.

Australia

PubMed Central

Belton, Suzanne

2017-01-01

Abstract This article adopts a human rights lens to consider Australian law and practice regarding elective abortion. As such, it considers Australian laws within the context of the right to equality, right to privacy, right to health, and right to life. After setting out the human rights framework and noting the connected nature of many of the rights (and their corresponding violations), the article shifts its focus to analyzing Australian law and practice within the framework of these rights. It considers the importance of decriminalizing abortion and regulating it as a standard medical procedure. It discusses the need to remove legal and practical restrictions on access to abortion, including financial obstacles and anti-abortion protestors. Further, it comments on the importance of facilitating access; for example, by keeping accurate health data, securing continuity of health care, increasing the availability of medical abortion, and ensuring appropriate care is provided to the most marginalized and vulnerable women. PMID:28630553

The mirror mechanism: recent findings and perspectives

PubMed Central

Rizzolatti, Giacomo; Fogassi, Leonardo

2014-01-01

Mirror neurons are a specific type of visuomotor neuron that discharge both when a monkey executes a motor act and when it observes a similar motor act performed by another individual. In this article, we review first the basic properties of these neurons. We then describe visual features recently investigated which indicate that, besides encoding the goal of motor acts, mirror neurons are modulated by location in space of the observed motor acts, by the perspective from which the others’ motor acts are seen, and by the value associated with the object on which others’ motor acts are performed. In the last part of this article, we discuss the role of the mirror mechanism in planning actions and in understanding the intention underlying the others’ motor acts. We also review some human studies suggesting that motor intention in humans may rely, as in the monkey, on the mirror mechanism. PMID:24778385

Applied choline-omics: lessons from human metabolic studies for the integration of genomics research into nutrition practice.

PubMed

West, Allyson A; Caudill, Marie A

2014-08-01

Nutritional genomics, defined as the study of reciprocal interactions among nutrients, metabolic intermediates, and the genome, along with other closely related nutritional -omic fields (eg, epigenomics, transcriptomics, and metabolomics) have become vital areas of nutrition study and knowledge. Utilizing results from human metabolic research on the essential nutrient choline, this article illustrates how nutrigenetic, nutrigenomic, and inter-related -omic research has provided new insights into choline metabolism and its effect on physiologic processes. Findings from highlighted choline research are also discussed in the context of translation to clinical and public health nutrition applications. Overall, this article underscores the utility of -omic research methods in elucidating nutrient metabolism as well as the potential for nutritional -omic concepts and discoveries to be broadly applied in nutritional practice. Copyright © 2014 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

Biomarkers for nonclinical infusion reactions in marketed biotherapeutics and considerations for study design.

PubMed

Mease, Kirsten M; Kimzey, Amy L; Lansita, Janice A

2017-06-01

The observation of an infusion reaction (IR) in a nonclinical study can cause concern among investigators and regulators in the development of biotherapeutics. Biomarkers can be informative to determine whether the reactions are immune-mediated or test-article related and if there is a potential risk to human subjects. IRs encompass a broad range of adverse events with a variety of triggers; the focus of this paper is IRs due to cytokine release syndrome or immune complex formation and the associated biomarkers. Such reactions generally do not preclude clinical development or marketing approval, because it is widely accepted that immune-mediated reactions in nonclinical species are not predictive of human outcomes. Several US approved products (from 2004 to 2016) have documented IRs in nonclinical species. This review article discusses recent examples, the biomarkers evaluated, and implications for study design and conduct.

[Characterization, influence and manipulation of the gastrointestinal microbiota in health and disease].

PubMed

García-Mazcorro, José F; Garza-González, Elvira; Marroquín-Cardona, Alicia G; Tamayo, José L

2015-01-01

The gastrointestinal tract harbors trillions of microorganisms that are indispensable for health. The gastrointestinal microbiota can be studied using culture and molecular methods. The applications of massive sequencing are constantly increasing, due to their high yield, increasingly accessible costs, and the availability of free software for data analysis. The present article provides a detailed review of a large number of studies on the gastrointestinal microbiota and its influence on human health; particular emphasis is placed on the evidence suggesting a relationship between the gastrointestinal microbial ecosystem and diverse physiological and immune/inflammatory processes. Discussion of the articles analyzed combines a medical approach and current concepts of microbial molecular ecology. The present revision aims to be useful to those interested in the gastrointestinal microbiota and its possible alteration to maintain, re-establish and enhance health in the human host. Copyright © 2015 Elsevier España, S.L.U. y AEEH y AEG. All rights reserved.

The clinical development process for a novel preventive vaccine: An overview.

PubMed

Singh, K; Mehta, S

2016-01-01

Each novel vaccine candidate needs to be evaluated for safety, immunogenicity, and protective efficacy in humans before it is licensed for use. After initial safety evaluation in healthy adults, each vaccine candidate follows a unique development path. This article on clinical development gives an overview on the development path based on the expectations of various guidelines issued by the World Health Organization (WHO), the European Medicines Agency (EMA), and the United States Food and Drug Administration (USFDA). The manuscript describes the objectives, study populations, study designs, study site, and outcome(s) of each phase (Phase I-III) of a clinical trial. Examples from the clinical development of a malaria vaccine candidate, a rotavirus vaccine, and two vaccines approved for human papillomavirus (HPV) have also been discussed. The article also tabulates relevant guidelines, which can be referred to while drafting the development path of a novel vaccine candidate.

More Human than Human.

PubMed

Lawrence, David

2017-07-01

Within the literature surrounding nonhuman animals on the one hand and cognitively disabled humans on the other, there is much discussion of where beings that do not satisfy the criteria for personhood fit in our moral deliberations. In the future, we may face a different but related problem: that we might create (or cause the creation of) beings that not only satisfy but exceed these criteria. The question becomes whether these are minimal criteria, or hierarchical, such that those who fulfill them to greater degree should be afforded greater consideration. This article questions the validity and necessity of drawing divisions among beings that satisfy the minimum requirements for personhood; considering how future beings-intelligent androids, synthezoids, even alternate-substrate sentiences-might fit alongside the "baseline" human. I ask whether these alternate beings ought to be considered different to us, and why this may or may not matter in terms of a notion of "human community." The film Blade Runner, concerned in large part with humanity and its key synthezoid antagonist Roy Batty, forms a framing touchstone for my discussion. Batty is stronger, faster, more resilient, and more intelligent than Homo sapiens. His exploits, far beyond the capability of normal humans, are contrasted with his frailty and transient lifespan, his aesthetic appreciation of the sights he has seen, and his burgeoning empathy. Not for nothing does his creator within the mythos term him "more human than human."

RESEARCH ON ENVIRONMENTAL HEALTH INTERVENTIONS: ETHICAL PROBLEMS AND SOLUTIONS

PubMed Central

RESNIK, DAVID B.; ZELDIN, DARRYL C.; SHARP, RICHARD R.

2014-01-01

This article reviews a variety of ethical issues one must consider when conducting research on environmental health interventions on human subjects. The paper uses the Kennedy Krieger Institute lead abatement study as well as a hypothetical asthma study to discuss questions concerning benefits and risks, risk minimization, safety monitoring, the duty to warn, the duty to report, the use of control groups, informed consent, equitable subject selection, privacy, conflicts of interest, and community consultation. Research on environmental health interventions can make an important contribution to our understanding of human health and disease prevention, provided it is conducted in a manner that meets prevailing scientific, ethical, and legal standards for research on human subjects. PMID:16220621

Human Trafficking, Mental Illness, and Addiction: Avoiding Diagnostic Overshadowing.

PubMed

Stoklosa, Hanni; MacGibbon, Marti; Stoklosa, Joseph

2017-01-01

This article reviews an emergency department-based clinical vignette of a trafficked patient with co-occurring pregnancy-related, mental health, and substance use disorder issues. The authors, including a survivor of human trafficking, draw on their backgrounds in addiction care, human trafficking, emergency medicine, and psychiatry to review the literature on relevant general health and mental health consequences of trafficking and propose an approach to the clinical complexities this case presents. In their discussion, the authors explicate the deleterious role of implicit bias and diagnostic overshadowing in trafficked patients with co-occurring addiction and mental illness. Finally, the authors propose a trauma-informed, multidisciplinary response to potentially trafficked patients. © 2017 American Medical Association. All Rights Reserved.

Manic Defences in Contemporary Society. The Psychocultural Approach.

PubMed

Rudan, Dusko; Jakovljevic, Miro; Marcinko, Darko

2016-12-01

The article discusses the impact of contemporary culture on the individual's personality. We used the "psychocultural" approach whose key feature is the amalgamation of theories and methods belonging to psychodynamic and psychosocial studies, as well as those used in the field of media and cultural studies. The idea of a potentially therapeutic effect of culture (therapy culture) can already been seen in Freud's and Lacan's texts, and it is often used in critical analyses of contemporary corporate culture, which is more or less developed in some parts of the world. In their criticisms, many contemporary authors emphasize that modern societies have a tendency towards the weakening of basic commitment, or lack thereof, to a social equivalent of Winnicott's concept of environmental provisions as an inalienable democratic right essential for human emotional and mental progress or emotional well-being. The article describes frequent resorting to the so-called manic defences that defensively distort, deny and obscure the awareness that a human being is not the omnipotent source of life, but instead depends on other human beings, and often tries to compensate for loss through various activities. The article describes excessive shopping as an activity that often serves as an attempt to find what was lost, i.e. to fill an emotional void. This solution (resorting to manic defences) is encouraged by contemporary culture, especially through promotional material (e.g. advertising). The main theses of this article are supported by quotations and data from world literature.

Impact of human emotions on physiological characteristics

NASA Astrophysics Data System (ADS)

Partila, P.; Voznak, M.; Peterek, T.; Penhaker, M.; Novak, V.; Tovarek, J.; Mehic, Miralem; Vojtech, L.

2014-05-01

Emotional states of humans and their impact on physiological and neurological characteristics are discussed in this paper. This problem is the goal of many teams who have dealt with this topic. Nowadays, it is necessary to increase the accuracy of methods for obtaining information about correlations between emotional state and physiological changes. To be able to record these changes, we focused on two majority emotional states. Studied subjects were psychologically stimulated to neutral - calm and then to the stress state. Electrocardiography, Electroencephalography and blood pressure represented neurological and physiological samples that were collected during patient's stimulated conditions. Speech activity was recording during the patient was reading selected text. Feature extraction was calculated by speech processing operations. Classifier based on Gaussian Mixture Model was trained and tested using Mel-Frequency Cepstral Coefficients extracted from the patient's speech. All measurements were performed in a chamber with electromagnetic compatibility. The article discusses a method for determining the influence of stress emotional state on the human and his physiological and neurological changes.

Quantum information, cognition, and music.

PubMed

Dalla Chiara, Maria L; Giuntini, Roberto; Leporini, Roberto; Negri, Eleonora; Sergioli, Giuseppe

2015-01-01

Parallelism represents an essential aspect of human mind/brain activities. One can recognize some common features between psychological parallelism and the characteristic parallel structures that arise in quantum theory and in quantum computation. The article is devoted to a discussion of the following questions: a comparison between classical probabilistic Turing machines and quantum Turing machines.possible applications of the quantum computational semantics to cognitive problems.parallelism in music.

Sexuality Education in Video Games: Recommendations for the Use of Video Games to Teach Human Sexuality Issues

ERIC Educational Resources Information Center

Gross, M. Scott

2005-01-01

This article provides a review of some of the currently available literature surrounding the academic study of video games. Many of these theoretical methods have been used to study film and television and are discussed here in order to frame the need for further examination of video games. Suggestions for the use of video games in the classroom…

Quantum information, cognition, and music

PubMed Central

Dalla Chiara, Maria L.; Giuntini, Roberto; Leporini, Roberto; Negri, Eleonora; Sergioli, Giuseppe

2015-01-01

Parallelism represents an essential aspect of human mind/brain activities. One can recognize some common features between psychological parallelism and the characteristic parallel structures that arise in quantum theory and in quantum computation. The article is devoted to a discussion of the following questions: a comparison between classical probabilistic Turing machines and quantum Turing machines.possible applications of the quantum computational semantics to cognitive problems.parallelism in music. PMID:26539139

The Genetics and Evolution of Human Skin Color: The Case of Desiree's Baby

ERIC Educational Resources Information Center

Schneider, Patricia

2004-01-01

This case explores the genetics and evolution of skin color, using a short story by Kate Chopin called "Desiree's Baby" as a starting point. Students read the story and discuss a series of questions probing the genetics of the family in the tale. Students then read an article about the evolution of skin color and write an essay analyzing the…

Discovering the Past through Data: Promoting the Design and Analysis of Original Data-Sets in History Undergraduate Courses in Hong Kong

ERIC Educational Resources Information Center

Kim, Loretta; Wong, Shun Han Rebekah

2015-01-01

This article discusses the objectives and outcomes of a project to enhance digital humanities training at the undergraduate level in a Hong Kong university. The co-investigators re-designed a multi-source data-set as an example and then taught a multi-step curriculum about gathering, organizing, and presenting original data to an introductory…

Mineral resource of the month: lead

USGS Publications Warehouse

Guberman, David E.

2010-01-01

The article discusses the properties and uses lead as a mineral resource. According to the author, lead is a corrosion-resistant, dense, ductile, and malleable blue-gray metal that has been used by humans for 5,000 years. Lead was first used in decorative, fixtures, roofs, pipes, and windows. The author says that lead is the fifth-most consumed metal based on tonnage after iron, aluminum, copper and zinc.

Becoming a Culturally Responsive Early Childhood Educator: A Tool to Support Reflection by Teachers Embarking on the Anti-Bias Journey

ERIC Educational Resources Information Center

Chen, Dora W.; Nimmo, John; Fraser, Heather

2009-01-01

As children begin to construct an understanding of human differences and similarities during their earliest years, early childhood teachers are challenged to be culturally responsive to the diversity of the children and families. Based on our review of the literature and other existing tools, this article discusses a framework for thinking about…

[Altered states of consciousness].

PubMed

Gora, E P

2005-01-01

The review of modern ideas concerning the altered states of consciousness is presented in this article. Various methods of entry into the altered states of consciousness are looked over. It is shown that the altered states of consciousness are insufficiently known, but important aspects of human being existence. The role of investigation of the altered states of consciousness for the creation of integrative scientific conception base is discussed.

Tiny tweaks, big changes: An alternative strategy to empower ethical culture of human research in anesthesia (A Taiwan Acta Anesthesiologica Taiwanica-Ethics Review Task Force Report).

PubMed

Luk, Hsiang-Ning; Ennever, John F; Day, Yuan-Ji; Wong, Chih-Shung; Sun, Wei-Zen

2015-03-01

For this guidance article, the Ethics Review Task Force (ERTF) of the Journal reviewed and discussed the ethics issues related to publication of human research in the field of anesthesia. ERTF first introduced international ethics principles and minimal requirements of reporting of ethics practices, followed by discussing the universal problems of publication ethics. ERTF then compared the accountability and methodology of several medical journals in assuring authors' ethics compliance. Using the Taiwan Institutional Review Board system as an example, ERTF expressed the importance of institutional review board registration and accreditation to assure human participant protection. ERTF presented four major human research misconducts in the field of anesthesia in recent years. ERTF finally proposed a flow-chart to guide journal peer reviewers and editors in ethics review during the editorial process in publishing. Examples of template languages applied in the Ethics statement section in the manuscript are expected to strengthen the ethics compliance of the authors and to set an ethical culture for all the stakeholders involved in human research. Copyright © 2015. Published by Elsevier B.V.

How informative is the mouse for human gut microbiota research?

PubMed Central

Nguyen, Thi Loan Anh; Vieira-Silva, Sara; Liston, Adrian; Raes, Jeroen

2015-01-01

The microbiota of the human gut is gaining broad attention owing to its association with a wide range of diseases, ranging from metabolic disorders (e.g. obesity and type 2 diabetes) to autoimmune diseases (such as inflammatory bowel disease and type 1 diabetes), cancer and even neurodevelopmental disorders (e.g. autism). Having been increasingly used in biomedical research, mice have become the model of choice for most studies in this emerging field. Mouse models allow perturbations in gut microbiota to be studied in a controlled experimental setup, and thus help in assessing causality of the complex host-microbiota interactions and in developing mechanistic hypotheses. However, pitfalls should be considered when translating gut microbiome research results from mouse models to humans. In this Special Article, we discuss the intrinsic similarities and differences that exist between the two systems, and compare the human and murine core gut microbiota based on a meta-analysis of currently available datasets. Finally, we discuss the external factors that influence the capability of mouse models to recapitulate the gut microbiota shifts associated with human diseases, and investigate which alternative model systems exist for gut microbiota research. PMID:25561744

How informative is the mouse for human gut microbiota research?

PubMed

Nguyen, Thi Loan Anh; Vieira-Silva, Sara; Liston, Adrian; Raes, Jeroen

2015-01-01

The microbiota of the human gut is gaining broad attention owing to its association with a wide range of diseases, ranging from metabolic disorders (e.g. obesity and type 2 diabetes) to autoimmune diseases (such as inflammatory bowel disease and type 1 diabetes), cancer and even neurodevelopmental disorders (e.g. autism). Having been increasingly used in biomedical research, mice have become the model of choice for most studies in this emerging field. Mouse models allow perturbations in gut microbiota to be studied in a controlled experimental setup, and thus help in assessing causality of the complex host-microbiota interactions and in developing mechanistic hypotheses. However, pitfalls should be considered when translating gut microbiome research results from mouse models to humans. In this Special Article, we discuss the intrinsic similarities and differences that exist between the two systems, and compare the human and murine core gut microbiota based on a meta-analysis of currently available datasets. Finally, we discuss the external factors that influence the capability of mouse models to recapitulate the gut microbiota shifts associated with human diseases, and investigate which alternative model systems exist for gut microbiota research. © 2015. Published by The Company of Biologists Ltd.

Recent trends in humanoid robotics research: scientific background, applications, and implications.

PubMed

Solis, Jorge; Takanishi, Atsuo

2010-11-01

Even though the market size is still small at this moment, applied fields of robots are gradually spreading from the manufacturing industry to the others as one of the important components to support an aging society. For this purpose, the research on human-robot interaction (HRI) has been an emerging topic of interest for both basic research and customer application. The studies are especially focused on behavioral and cognitive aspects of the interaction and the social contexts surrounding it. As a part of these studies, the term of "roboethics" has been introduced as an approach to discuss the potentialities and the limits of robots in relation to human beings. In this article, we describe the recent research trends on the field of humanoid robotics. Their principal applications and their possible impact are discussed.

Odontogenic epithelial stem cells: hidden sources.

PubMed

Padma Priya, Sivan; Higuchi, Akon; Abu Fanas, Salem; Pooi Ling, Mok; Kumari Neela, Vasantha; Sunil, P M; Saraswathi, T R; Murugan, Kadarkarai; Alarfaj, Abdullah A; Munusamy, Murugan A; Kumar, Suresh

2015-12-01

The ultimate goal of dental stem cell research is to construct a bioengineered tooth. Tooth formation occurs based on the well-organized reciprocal interaction of epithelial and mesenchymal cells. The dental mesenchymal stem cells are the best explored, but because the human odontogenic epithelium is lost after the completion of enamel formation, studies on these cells are scarce. The successful creation of a bioengineered tooth is achievable only when the odontogenic epithelium is reconstructed to produce a replica of natural enamel. This article discusses the untapped sources of odontogenic epithelial stem cells in humans, such as those present in the active dental lamina in postnatal life, in remnants of dental lamina (the gubernaculum cord), in the epithelial cell rests of Malassez, and in reduced enamel epithelium. The possible uses of these stem cells in regenerative medicine, not just for enamel formation, are discussed.

Islamic perspective on human cloning and stem cell research.

PubMed

Larijani, B; Zahedi, F

2004-12-01

Recent advances in the field of cloning and stem cell research have introduced new hope for treatment of serious diseases. But this promise has been accompanied by enormous questions. Currently, cloning is a matter of public discussion. It is rare that a field of science causes debate and challenge not only among scientists but also among ethicists, religious scholars, governments, and politicians. One important concern is religious arguments. Various religions have different attitudes toward the morality of these subjects; even within a particular religious tradition there is a diversity of opinions. The following article briefly reviews Islamic perspectives about reproductive/therapeutic cloning and stem cell research. The majority of Muslim jurists distinguish between reproductive and therapeutic cloning. The moral status of the human embryo, the most sensitive and disputed point in this debate, is also discussed according to Holy Quran teachings.

Body of evidence: integrating Eduard Pernkopf's Atlas into a librarian-led medical humanities seminar.

PubMed

Mages, Keith C; Lohr, Linda A

2017-04-01

Anatomical subjects depicted in Eduard Pernkopf's richly illustrated Topographische Anatomie des Menschen may be victims of the Nazi regime. Special collections librarians in the history of medicine can use this primary resource to initiate dialogs about ethics with medical students. Reported here is the authors' use of Pernkopf's Atlas in an interactive medical humanities seminar designed for third-year medical students. Topical articles, illustrations, and interviews introduced students to Pernkopf, his Atlas , and the surrounding controversies. We aimed to illustrate how this controversial historical publication can successfully foster student discussion and ethical reflection. Pernkopf's Atlas and our mix of contextual resources facilitated thoughtful discussions about history and ethics amongst the group. Anonymous course evaluations showed student interest in the subject matter, relevance to their studies, and appreciation of our special collection's space and contents.

Basophils and allergic inflammation

PubMed Central

Siracusa, Mark C.; Kim, Brian S.; Spergel, Jonathan M.; Artis, David

2013-01-01

Basophils were discovered by Paul Ehrlich in 1879 and represent the least abundant granulocyte population in mammals. The relative rarity of basophils and their phenotypic similarities with mast cells resulted in this cell lineage being historically overlooked, both clinically and experimentally. However, recent studies in humans and murine systems have shown that basophils perform non-redundant effector functions and significantly contribute to the development and progression of TH2 cytokine-mediated inflammation. Although the potential functions of murine and human basophils have provoked some controversy, recent genetic approaches indicate that basophils can migrate into lymphoid tissues and, in some circumstances, cooperate with other immune cells to promote optimal TH2 cytokine responses in vivo. This article provides a brief historical perspective on basophil-related research and discusses recent studies that have identified previously unappreciated molecules and pathways that regulate basophil development, activation and function in the context of allergic inflammation. Further, we highlight the unique effector functions of basophils and discuss their contributions to the development and pathogenesis of allergic inflammation in human disease. Finally, we discuss the therapeutic potential of targeting basophils in preventing or alleviating the development and progression of allergic inflammation. PMID:24075190

[Experience of a research Ethics Committee and the challenges of the new Chilean legislation on research in human beings].

PubMed

Oyarzún G, Manuel; Pinto C, María Eugenia; Raineri B, Gina G; Amigo, Hugo; Cifuentes O, Lucía; González, María Julieta; Horwitz, Nina; Marshall F, Claudia; Orellana V, Gricel

2014-07-01

The welfare of research participants must be guaranteed by international ethical standards. This article communicates the procedures of the Research Ethics Committee of the School of Medicine, University of Chile (CEISH). The new Chilean legislation on research in human beings is also discussed. Law 20.120: "On scientific research in human beings, its genome and forbidding human cloning" establishes the ethical principles that must be accomplished in every research involving human beings. Article 28 of the Law 20.584 "Regulation of the rights and duties of health care users", forbids the participation of handicapped people who cannot express their will in scientific research. Article 13 states that people not related directly with patient care cannot have access to his clinical records (with the exception of people with notarial authorization by the patient). CEISH proposes that, in case of people with intellectual deficiency, the decision to approve a scientific research should be analyzed on an individual basis. If the person is capable of expressing his or her will or has stated his or her consent beforehand, the research can be authorized. If the person cannot express his or her will, the scientific research cannot take place. In prospective studies, a consent from the patient and an authorization of the health authority should be required to access clinical records. In retrospective studies, consent should be obtained from the patient when personal information is going to be used. If the information is nameless, the consent can be disregarded.

Hans Loewald and the transformation of passion.

PubMed

Lang, Frances

2009-01-01

Loewald's writing is notable for its musicality as well as for its content. In this article, possible early determinants of this salient aspect of his work are discussed. The intensity of Loewald's regard for Freud and, in particular, his attentiveness to Freud's language are explored. Loewald's views on the legitimacy of transference as an ongoing aspect of human motivation is discussed, along with the possible emergence in Loewald's own writing of transferences toward Freud--both oedipal level conflicts regarding parricide and preoedipal concerns regarding unity and separation. Sublimation, a process Loewald viewed as an extension of internalization, is seen as foundational to his achievement.

On hitting children: a review of corporal punishment in the United States.

PubMed

Knox, Michele

2010-01-01

Research has clearly demonstrated associations between corporal punishment of children and maladaptive behavior patterns such as aggression and delinquency. Hitting children is an act of violence and a clear violation of children's human rights. In this article, the position of the United States on corporal punishment of children is discussed. Professional and international progress on ending corporal punishment is explained, and the relationship between corporal punishment and child abuse is discussed. An appeal is made for prevention efforts such as parent education and removal of social sanctions for hitting children that may hold significant promise for preventing child maltreatment.

Barcelona 2002: law, ethics, and human rights. An advocacy and political conference produces a consensus: effective action is urgently required.

PubMed

Anderson, Terje

2002-12-01

From the deep sense of frustration about the gap between what is possible and what is actually happening, a clear consensus emerged at the XIV International AIDS Conference that effective action is urgently required. This article is based on a presentation on 12 July 2002, the last day of the conference, by Terje Anderson, the rapporteur for Track G. The article presents a summary of the discussions in Track G on topics such as advocacy strategies, the use of the law, the use of a human rights framework and approach, the role of people living with HIV/AIDS, and the need to mobilize sufficient resources. The article states and then critically examines some of the consensus positions that emerged from the conference--specifically, the goal to have three million people on antiretroviral therapy by 2005; the notion that the debate around prevention versus care is over; and the idea that the key issue is no longer what we do, but how to secure the commitment and the resources to do it. The article states that the fight against HIV/AIDS must be fought on a political plane, and that it is the responsibility of everyone working in AIDS to engage our leaders. The article concludes by asking whether we really have the courage and the perseverance to turn our knowledge and our commitment into action.

The ownership of human body: an islamic perspective.

PubMed

Aramesh, Kiarash

2009-01-01

Using human dead body for medical purposes is a common practice in medical schools and hospitals throughout the world. Iran, as an Islamic country is not an exception. According to the Islamic view, the body, like the soul, is a "gift" from God; therefore, human being does not possess absolute ownership on his or her body. But, the ownership of human beings on their bodies can be described as a kind of "stewardship". Accordingly, any kind of dissection or mutilation of the corpse is forbidden, even with the informed consent of the dead or his/her relatives. The exception of this principle is when such procedures are necessary for saving lives of other persons. In this article using the human dead body for medical education, research and treatment is discussed and the perspective of Iranian Shiite religious scholars in this regard is explained.

Introduction: U.S. Homophile Internationalism.

PubMed

Stein, Marc

2017-01-01

This article introduces "U.S. Homophile Internationalism," a special issue of the Journal of Homosexuality. The introduction provides a broad overview of the "U.S. Homophile Internationalism" archive and exhibit, which was published on the Outhistory Web site in 2015. The archive and exhibit consists of more than 800 U.S. homophile magazine articles, letters, and other items that referenced non-U.S. regions of the world from 1953 to 1964. The essays in the special issue focus on (1) Africa; (2) Asia and the Pacific; (3) Canada; (4) Latin America and the Caribbean; (5) the Middle East; and (6) Russia, the Soviet Union, and Eastern Europe. There is also an article that addresses the public history and digital humanities dimensions of the project. The introduction concludes by discussing the essays' common goals, themes, and concerns.

Aviation human factors research in U.S. universities: Potential contributions to national needs

NASA Technical Reports Server (NTRS)

Key Dismukes, R.

1994-01-01

Univesity research can make vital contributions to national needs in aviation human factors (AHF). This article examines the types of expertise and facilities available in universities and explores how university capabilities complement the work of government laboratories. The AHF infrastructure is discussed and compared to other fields of applied research. Policy and funding issues are also examined. This study is based on a survey conducted by the author, which included site visits to several universities, telephone interviews with faculty members at other universities, and a search of the AHF research literature.

Methods for Human Dehydration Measurement

NASA Astrophysics Data System (ADS)

Trenz, Florian; Weigel, Robert; Hagelauer, Amelie

2018-03-01

The aim of this article is to give a broad overview of current methods for the identification and quantification of the human dehydration level. Starting off from most common clinical setups, including vital parameters and general patients' appearance, more quantifiable results from chemical laboratory and electromagnetic measurement methods will be reviewed. Different analysis methods throughout the electromagnetic spectrum, ranging from direct current (DC) conductivity measurements up to neutron activation analysis (NAA), are discussed on the base of published results. Finally, promising technologies, which allow for an integration of a dehydration assessment system in a compact and portable way, will be spotted.

[Lights, art, science - action!].

PubMed

Lopes, Thelma

2005-01-01

The article offers some reflections on the main interactions between theater, science, and technology down through the history of theater. Based on our experience at "Science in the Spotlight", part of the Casa de Oswaldo Cruz's Museum of Life, we discuss how these interactions can be part of a science museum's daily activities. We use the word 'science' in its broad sense, encompassing not only the natural but human sciences as well; likewise, we use the word 'technology' as it relates to applied science. Art and science are understood here as creative processes, as ways of representing the world and expressing human knowledge.

[Suicide and euthanasia : Discourse on physician-assisted suicide].

PubMed

Lewitzka, Dr U; Bauer, R

2016-05-01

Suicidal thoughts and behavior have been a part of human nature since the beginning of mankind. In his autobiographical work From my Life: Poetry and Truth Goethe summarized two important aspects: "Suicide is an event of human nature which, whatever may be said and done with respect to it, demands the sympathy of every man, and in every epoch must be discussed anew". The authors of this article aim to motivate the readership to question and analyze this complex topic and the accompanying multifaceted positions with a summarized presentation of historical aspects and the more recent political developments.

Toward a theory of holistic needs and the brain.

PubMed

Silton, Nava R; Flannelly, Laura T; Flannelly, Kevin J; Galek, Kathleen

2011-01-01

This article reviews Maslow's theory of motivation wherein he proposes a hierarchy of human needs. First, it describes the principal elements of Maslow's theory and discusses considerations relating to the flexibility of the hierarchy. Second, it explains the relationship among Maslow's theory of human needs, attachment theory, and evolutionary threat assessment system theory. Third, it provides an overview of the brain structures posited to be involved in attachment and evolutionary threat assessment system theory and their relation to Maslow's hierarchy. Finally, it explains how the 3 theories converge to form a theory of holistic needs.

Nanotechnology in global medicine and human biosecurity: private interests, policy dilemmas, and the calibration of public health law.

PubMed

Faunce, Thomas A

2007-01-01

This paper considers how best to approach dilemmas posed to global health and biosecurity policy by increasing advances in practical applications of nanotechnology. The type of nano-technology policy dilemmas discussed include: (1) expenditure of public funds, (2) public-funded research priorities, (3) public confidence in government and science and, finally, (4) public safety. The article examines the value in this context of a legal obligation that the development of relevant public health law be calibrated against less corporate-influenced norms issuing from bioethics and international human rights.

Not the Usual Viral Suspects: Parvovirus B19, West Nile Virus, and Human T-Cell Lymphotrophic Virus Infections After Kidney Transplantation.

PubMed

Razonable, Raymund R

2016-09-01

Kidney transplant recipients are at increased risk of developing clinical disease due to uncommon opportunistic viral pathogens. Refractory anemia is classically associated with parvovirus B19 infection. West Nile virus has the propensity to cause fever and neurologic symptoms, while spastic paresis and lymphoma can be triggered by human T cell lymphotrophic virus. In this review article, the epidemiology, clinical manifestations, diagnosis and treatment of less common viruses are discussed in the setting of kidney transplantation. Copyright © 2016 Elsevier Inc. All rights reserved.

Models of Pilot Behavior and Their Use to Evaluate the State of Pilot Training

NASA Astrophysics Data System (ADS)

Jirgl, Miroslav; Jalovecky, Rudolf; Bradac, Zdenek

2016-07-01

This article discusses the possibilities of obtaining new information related to human behavior, namely the changes or progressive development of pilots' abilities during training. The main assumption is that a pilot's ability can be evaluated based on a corresponding behavioral model whose parameters are estimated using mathematical identification procedures. The mean values of the identified parameters are obtained via statistical methods. These parameters are then monitored and their changes evaluated. In this context, the paper introduces and examines relevant mathematical models of human (pilot) behavior, the pilot-aircraft interaction, and an example of the mathematical analysis.

A Critical Assessment of Research on Neurotransmitters in Alzheimer's Disease.

PubMed

Reddy, P Hemachandra

2017-01-01

The purpose of this mini-forum, "Neurotransmitters and Alzheimer's Disease", is to critically assess the current status of neurotransmitters in Alzheimer's disease. Neurotransmitters are essential neurochemicals that maintain synaptic and cognitive functions in mammals, including humans, by sending signals across pre- to post-synaptic neurons. Authorities in the fields of synapses and neurotransmitters of Alzheimer's disease summarize the current status of basic biology of synapses and neurotransmitters, and also update the current status of clinical trials of neurotransmitters in Alzheimer's disease. This article discusses the prevalence, economic impact, and stages of Alzheimer's dementia in humans.

Legal aspects of genetic information.

PubMed Central

Andrews, L. B.

1991-01-01

The federally funded Human Genome Initiative will lead to the development of new capabilities to learn about an individual's genetic status. Legal issues are raised concerning patients' and other parties' access to that information. This article discusses the effect of existing statutes and case law on three pivotal questions: To what sort of information are people entitled? What control should people have over their genetic information? Do people have a right to refuse genetic information? The article emphasizes that the law protects a patient's right to obtain or refuse genetic information about oneself, as well as the right to control the dissemination of that information to others. PMID:1897258

Security of information in IT systems

NASA Astrophysics Data System (ADS)

Kaliczynska, Malgorzata

2005-02-01

The aim of the paper is to increase human awareness of the dangers connected with social engineering methods of obtaining information. The article demonstrates psychological and sociological methods of influencing people used in the attacks on IT systems. Little known techniques are presented about one of the greater threats that is electromagnetic emission or corona effect. Moreover, the work shows methods of protecting against this type of dangers. Also, in the paper one can find information on devices made according to the TEMPEST technology. The article not only discusses the methods of gathering information, but also instructs how to protect against its out-of-control loss.

Teaching humanism.

PubMed

Stern, David T; Cohen, Jordan J; Bruder, Ann; Packer, Barbara; Sole, Allison

2008-01-01

As the "passion that animates authentic professionalism," humanism must be infused into medical education and clinical care as a central feature of medicine's professionalism movement. In this article, we discuss a current definition of humanism in medicine. We will also provide detailed descriptions of educational programs intended to promote humanism at a number of medical schools in the United States (and beyond) and identify the key factors that make these programs effective. Common elements of programs that effectively teach humanism include: (1) opportunities for students to gain perspective in the lives of patients; (2) structured time for reflection on those experiences; and (3) focused mentoring to ensure that these events convert to positive, formative learning experiences. By describing educational experiences that both promote and sustain humanism in doctors, we hope to stimulate the thinking of other medical educators and to disseminate the impact of these innovative educational programs to help the profession meet its obligation to provide the public with humanistic physicians.

Animal models of disease shed light on Nipah virus pathogenesis and transmission.

PubMed

de Wit, Emmie; Munster, Vincent J

2015-01-01

Nipah virus is an emerging virus infection that causes yearly disease outbreaks with high case fatality rates in Bangladesh. Nipah virus causes encephalitis and systemic vasculitis, sometimes in combination with respiratory disease. Pteropus species fruit bats are the natural reservoir of Nipah virus and zoonotic transmission can occur directly or via an intermediate host; human-to-human transmission occurs regularly. In this review we discuss the current state of knowledge on the pathogenesis and transmission of Nipah virus, focusing on dissemination of the virus through its host, known determinants of pathogenicity and routes of zoonotic and human-to-human transmission. Since data from human cases are sparse, this knowledge is largely based on the results of studies performed in animal models that recapitulate Nipah virus disease in humans. Published 2014. This article is a U.S. Government work and is in the public domain in the USA.

Spaceflight and protein metabolism, with special reference to humans

NASA Technical Reports Server (NTRS)

Stein, T. P.; Gaprindashvili, T.

1994-01-01

Human space missions have shown that human spaceflight is associated with a loss of body protein. Specific changes include a loss of lean body mass, decreased muscle mass in the calves, decreased muscle strength, and changes in plasma proteins and amino acids. The major muscle loss is believed to be associated with the antigravity (postural) muscle. The most significant loss of protein appears to occur during the first month of flight. The etiology is believed to be multifactorial with contributions from disuse atrophy, undernutrition, and a stress type of response. This article reviews the results of American and Russian space missions to investigate this problem in humans, monkeys, and rats. The relationship of the flight results with ground-based models including bedrest for humans and hindlimb unweighting for rats is also discussed. The results suggest that humans adapt to spaceflight much better than either monkeys or rats.

A VIEW OF TURKEY AND EUROPEAN RELATIONS FROM THE PERSPECTIVE OF MEDICAL LEGISLATION: AN ASSESMENT OF STATE OF PLAY

PubMed Central

Ekmekçi, Perihan Elif; Arda, Berna

2015-01-01

The aim of this paper is to reflect the situation of health legislation alignment in Turkey in its accession process to the European Union and Customs Union Agreement, and to discuss the the EU’s health priorities of in parallel with the Turkish ones. The health legislation alignment processes consist of three titles which are: European Union alignment process, the harmonization done in the framework of membership to Council of Europe, and the obligations under the Customs Union Agreement. Significant human resources are required for the adoption of the legislations which make ethically imperative the discussion of whether there is a harmony among the priorities of both parities. Unless this harmony and paralellisim is shown, the human resources appointed for the adoption of health legislation process would not prove their efficiency and effectiveness. In this article, the Customs Union and formal negotiations for full EU membership are included in the phrase “the alignment process to European Union”. Council Decisions 1/95 and 2/97 ground on the obligations provided by the Customs Union Agreement. The reference document used to discuss the formal negotiation process for full membership to European Union is the Turkish National Program for the Adoption of the EU Acquis 2008–2013. The legislative obligations of Turkey arising from its membership of the Council of Europe, which has significant contributions to the medical legislation especially in the field of medical ethics, are also included in this article. PMID:26269696

Innovative taught MSc in Medical Visualisation and Human Anatomy.

PubMed

Clunie, Lauren; Livingstone, Daniel; Rea, Paul M

2015-06-01

A relatively new, fully accredited MSc in Medical Visualisation and Human Anatomy, is now offered through a joint collaboration with the Laboratory of Human Anatomy, University of Glasgow and the Digital Design Studio, Glasgow School of Art. This degree combines training in digital technologies and intensive human anatomy training as a result of a long-standing successful partnership between these two esteemed institutes. The student also has to complete a research dissertation which encompasses both the digital perspective and a related medical, dental, surgical, veterinary (comparative anatomy) or life science specialty to enhance development in the digital field for a variety of specialties. This article discusses the background in development of this degree, the course structure and the career prospects and destinations for graduates of this unique degree programme.

Preventing and Investigating Horse-Related Human Injury and Fatality in Work and Non-Work Equestrian Environments: A Consideration of the Workplace Health and Safety Framework

PubMed Central

Chapman, Meredith; Thompson, Kirrilly

2016-01-01

Simple Summary Attempts to reduce horse-related injuries and fatalities to humans have mostly focused on personal protective equipment like helmets. In organizational contexts, such technical interventions are considered secondary to reducing the frequency and severity of accidents. In this article, we describe the Workplace Health and Safety (WHS) framework that has been associated with reduced risks in industries and organisations. We consider how such a framework could be used to reduce horse-related risks in workplaces, as well as non-work equestrian competition and leisure environments. In this article, we propose that the simplicity and concepts of the WHS framework can provide risk mitigation benefits to both work and non-work equine identities. Abstract It has been suggested that one in five riders will be injured due to a fall from a horse, resulting in severe head or torso injuries. Attempts to reduce injury have primarily focussed on low level risk controls, such as helmets. In comparison, risk mitigation in high risk workplaces and sports is directed at more effective and preventative controls like training, consultation, safe work procedures, fit for purpose equipment and regular Workplace Health and Safety (WHS) monitoring. However, there has been no systematic consideration of the risk-reduction benefits of applying a WHS framework to reducing horse-related risks in workplaces, let alone competition or leisure contexts. In this article, we discuss the different dimensions of risk during human–horse interaction: the risk itself, animal, human and environmental factors and their combinations thereof. We consider the potential of the WHS framework as a tool for reducing (a) situation-specific hazards, and (b) the risks inherent in and arising from human–horse interactions. Whilst most—if not all—horses are unpredictable, the majority of horse-related injuries should be treated as preventable. The article concludes with a practical application of WHS to prevent horse-related injury by discussing effective evidence-based guidelines and regulatory monitoring for equestrian sectors. It suggests that the WHS framework has significant potential not only to reduce the occurrence and likelihood of horse-related human accident and injury, but to enable systematic accident analysis and investigation of horse-related adverse events. PMID:27164148

Organismal death, the dead-donor rule and the ethics of vital organ procurement.

PubMed

Symons, Xavier; Chua, Reginald Mary

2018-06-19

Several bioethicists have recently discussed the complexity of defining human death, and considered in particular how our definition of death affects our understanding of the ethics of vital organ procurement. In this brief paper, we challenge the mainstream medical definition of human death-namely, that death is equivalent to total brain failure-and argue with Nair-Collins and Miller that integrated biological functions can continue even after total brain failure has occurred. We discuss the implications of Nair-Collins and Miller's argument and suggest that it may be necessary to look for alternative biological markers that reliably indicate the death of a human being. We reject the suggestion that we should abandon the dead-donor criteria for organ donation. Rather than weaken the ethical standards for vital organ procurement, it may be necessary to make them more demanding. The aim of this paper is not to justify the dead donor rule. Rather, we aim to explore the perspective of those who agree with critiques of the whole brain and cardiopulmonary definitions of death but yet disagree with the proposal that we should abandon the dead-donor rule. We will consider what those who want to retain the dead-donor rule must argue in light of Nair-Collins and Miller's critique. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

[The status of human cloning in the international setting].

PubMed

Rey del Castillo, Javier

2006-01-01

The General Assembly of the United Nations submitted a Declaration on Human Cloning in March 2005. The text of such Declaration was the result of a difficult and long process, taking more than three years. Being a Declaration instead of a Resolution, it has not legal capability in inforcing United Nations members to act according to its recommendations. This article begins with an explanation of several terms referred to cloning. Different countries' legislation on cloning is analyzed. Positions of the same countries at the Convention of the United Nations are as well analyzed. Comparing both countries' views shows that national legislation on cloning is independent and orientated by some countries' particular interests and biological and ethical views on these issues. Future developments on human cloning and its applications will be shared among all countries, both the ones currently allowing and supporting "therapeutic" cloning and the ones now banning it. In such case, it would be important to reach agreements on these issues at an international level. The article discusses possible legislative developments and offers some proposals to reach such agreements.

Ultra-mini PNL (UMP): Material, indications, technique, advantages and results.

PubMed

Desai, Janak D

2017-01-01

Stone disease has afflicted mankind since centuries; records from ancient civilisations of India and Egypt have shown stones in human bodies. The scientific mind of humans has always made smart endeavours to remove the kidney stones. From large instruments made like the beaks of different animals and birds in 600 BC (Indian civilisation) to extremely sophisticated and miniaturised endoscopic intruments of today the human race has travelled a long way. The theme has always been to remove the stones with minimal morbidity and mortality and with minimum pain to the patient. The article takes you through the journey of instruments used in 600 BC until today. The story of instrumentation is a symbiosis of the medical minds along with engineering advances. The story of miniaturisation could not have moved further without the development of lasers, fiberoptics and sophisticated cameras. As the field stands today, we remove more complex stones by larger endoscopic intervention and smaller stones by miniaturised instruments. The article discusses all the merits and shortcomings of various techniques: from open surgery to standard PCNL to Mini PCNL to Ultra- Mini PCNL to Micro-PCNL.

Overdiagnosis across medical disciplines: a scoping review.

PubMed

Jenniskens, Kevin; de Groot, Joris A H; Reitsma, Johannes B; Moons, Karel G M; Hooft, Lotty; Naaktgeboren, Christiana A

2017-12-27

To provide insight into how and in what clinical fields overdiagnosis is studied and give directions for further applied and methodological research. Scoping review. Medline up to August 2017. All English studies on humans, in which overdiagnosis was discussed as a dominant theme. Studies were assessed on clinical field, study aim (ie, methodological or non-methodological), article type (eg, primary study, review), the type and role of diagnostic test(s) studied and the context in which these studies discussed overdiagnosis. From 4896 studies, 1851 were included for analysis. Half of all studies on overdiagnosis were performed in the field of oncology (50%). Other prevalent clinical fields included mental disorders, infectious diseases and cardiovascular diseases accounting for 9%, 8% and 6% of studies, respectively. Overdiagnosis was addressed from a methodological perspective in 20% of studies. Primary studies were the most common article type (58%). The type of diagnostic tests most commonly studied were imaging tests (32%), although these were predominantly seen in oncology and cardiovascular disease (84%). Diagnostic tests were studied in a screening setting in 43% of all studies, but as high as 75% of all oncological studies. The context in which studies addressed overdiagnosis related most frequently to its estimation, accounting for 53%. Methodology on overdiagnosis estimation and definition provided a source for extensive discussion. Other contexts of discussion included definition of disease, overdiagnosis communication, trends in increasing disease prevalence, drivers and consequences of overdiagnosis, incidental findings and genomics. Overdiagnosis is discussed across virtually all clinical fields and in different contexts. The variability in characteristics between studies and lack of consensus on overdiagnosis definition indicate the need for a uniform typology to improve coherence and comparability of studies on overdiagnosis. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Advanced glycation end products (AGEs) in oral pathology.

PubMed

Ilea, Aranka; Băbţan, Anida M; Boşca, Bianca A; Crişan, Maria; Petrescu, Nausica B; Collino, Massimo; Sainz, Rosa M; Gerlach, Jared Q; Câmpian, Radu Septimiu

2018-05-18

Maillard advanced glycation end products (AGEs) are connected with high dry temperature food processing, color and flavor modification of food products. Oral cavity pathology is strongly influenced by dietary intake. The aim of the present paper is to update current data regarding the sources and metabolism of AGEs, their impact on oral cavity tissues, to discuss and suggest new approaches for the early diagnosis and efficient treatment of AGEs-related oral pathology. This paper is a narrative review of the studies discussing AGEs and mainly the dietary AGEs (dAGEs) sources, metabolism, linkage to general diseases, and specifically the oral cavity pathology. The authors used "PUBMED" and MeSH for the finding of English written and published articles concerning AGEs. There were used the next keywords association: "advanced glycation end products- AGEs" AND "Maillard products", "AGEs" AND "diet-related disease, "AGEs" AND "salivary biosensor", "AGEs" AND "metabolic syndrome AGEs", "AGEs" AND "oral pathology", "AGEs" AND "dentin AGEs" OR "periodontal AGEs", "AGEs" AND "diagnosis and monitoring". The authors used free full-text articles to determine the etiology and physiopathology of AGEs, their association with general diseases and oral cavity disease, assessment methods used in biofluids and tissues, AGEs prevention and treatment approaches. Articles concerning AGEs etiology, metabolism and effect in the human body and specific implication in oral pathology were selected. There were no exclusion criteria in what concerns the study design. Studies in other language than English and articles abstracts were excluded. Criteria of inclusion were free full-text articles written in English. Equally human and animal model studies were included. Regarding the date of publication, all subjects concerning glycation products after 1953 (first published article) were included. Evidence show that AGEs are responsible for inducing low intensity chronic inflammation and thereby, for initiating and/or aggravating chronic diseases. Nowadays, research has demonstrated a significant association between AGEs and dental or periodontal pathology. Moreover, salivary AGEs are consistent with the levels of AGEs in other biological fluids and are correlated with the general and oral pathology. Assessment of salivary AGEs could be a reliable tool for early diagnosis and monitoring diet-related disease. Copyright © 2018 Elsevier Ltd. All rights reserved.

The late Pleistocene colonization of South America: an interdisciplinary perspective.

PubMed

Rothhammer, Francisco; Dillehay, Tom D

2009-09-01

In this article, we briefly review scenarios for the first peopling of the New World, including the Clovis First/Single Origin, Tripartite, and Dual Migration models. We then discuss bioanthropological, molecular genetic, archaeological and biogeographic evidence for the peopling of the continent. To conclude, we draw on different lines of evidence to make inferences concerning the timing, direction, and type of early human dispersion in South America.

Driven to Distraction.

PubMed

Strayer, David L; Cooper, Joel M

2015-12-01

We address several themes that emerged in the commentaries related to our target article. First, we consider the relationship between cognitive distraction and crash risk. Second, we discuss the development of our cognitive distraction scale. Third, we weigh issues of self-regulation, appropriate baselines, and satisficing. Finally, we identify several areas where additional research is needed to refine our understanding of driver distraction and crash risk. © 2015, Human Factors and Ergonomics Society.

Climate change and ecological public health.

PubMed

Goodman, Benny

2015-02-17

Climate change has been identified as a serious threat to human health, associated with the sustainability of current practices and lifestyles. Nurses should expand their health promotion role to address current and emerging threats to health from climate change and to address ecological public health. This article briefly outlines climate change and the concept of ecological public health, and discusses a 2012 review of the role of the nurse in health promotion.

Humanity and Social Responsibility, Solidarity, and Social Rights.

PubMed

Ahola-Launonen, Johanna

2016-04-01

This article discusses the suggestion of having the notion of solidarity as the foundational value for welfare scheme reforms. Solidarity is an emerging concept in bioethical deliberations emphasizing the need for value-oriented discussion in revising healthcare structures, and the notion has been contrasted with liberal justice and rights. I suggest that this contrast is unnecessary, flawed, and potentially counterproductive. As necessary as the sense of solidarity is in a society, it is an insufficient concept to secure the goals related to social responsibility. The discussion on solidarity is also based on a questionable sense of nostalgia. Furthermore, solidarity and liberal justice share essential objectives concerning welfare schemes; therefore, the question arises whether the proper comparison should in the first place be within justice and solidarity.

What Pinnipeds Have to Say about Human Speech, Music, and the Evolution of Rhythm.

PubMed

Ravignani, Andrea; Fitch, W Tecumseh; Hanke, Frederike D; Heinrich, Tamara; Hurgitsch, Bettina; Kotz, Sonja A; Scharff, Constance; Stoeger, Angela S; de Boer, Bart

2016-01-01

Research on the evolution of human speech and music benefits from hypotheses and data generated in a number of disciplines. The purpose of this article is to illustrate the high relevance of pinniped research for the study of speech, musical rhythm, and their origins, bridging and complementing current research on primates and birds. We briefly discuss speech, vocal learning, and rhythm from an evolutionary and comparative perspective. We review the current state of the art on pinniped communication and behavior relevant to the evolution of human speech and music, showing interesting parallels to hypotheses on rhythmic behavior in early hominids. We suggest future research directions in terms of species to test and empirical data needed.

To Live or to Die: Prosurvival Activity of PPARγ in Cancers

PubMed Central

Wang, Y. Lynn; Miao, Qi

2008-01-01

The role of PPARγ in tumorigenesis is controversial. In this article, we review and analyze literature from the past decade that highlights the potential proneoplastic activity of PPARγ. We discuss the following five aspects of the nuclear hormone receptor and its agonists: (1) relative expression of PPARγ in human tumor versus normal tissues; (2) receptor-dependent proneoplastic effects; (3) impact of PPARγ and its agonists on tumors in animal models; (4) clinical trials of thiazolidinediones (TZDs) in human malignancies; (5) TZDs as chemopreventive agents in epidemiology studies. The focus is placed on the most relevant in vivo animal models and human data. In vitro cell line studies are included only when the effects are shown to be dependent on the PPARγ receptor. PMID:18784849

What Pinnipeds Have to Say about Human Speech, Music, and the Evolution of Rhythm

PubMed Central

Ravignani, Andrea; Fitch, W. Tecumseh; Hanke, Frederike D.; Heinrich, Tamara; Hurgitsch, Bettina; Kotz, Sonja A.; Scharff, Constance; Stoeger, Angela S.; de Boer, Bart

2016-01-01

Research on the evolution of human speech and music benefits from hypotheses and data generated in a number of disciplines. The purpose of this article is to illustrate the high relevance of pinniped research for the study of speech, musical rhythm, and their origins, bridging and complementing current research on primates and birds. We briefly discuss speech, vocal learning, and rhythm from an evolutionary and comparative perspective. We review the current state of the art on pinniped communication and behavior relevant to the evolution of human speech and music, showing interesting parallels to hypotheses on rhythmic behavior in early hominids. We suggest future research directions in terms of species to test and empirical data needed. PMID:27378843