Mickaelian, A. M. 1; Astsatryan, H. V. 2; Magakian, T. Yu. 1; Sargsyan, L. A. 1; Gigoyan, K. S. 1; Erastova, L. K. 1; Gyulzadyan, M. V. 1; Sinamyan, P. K. 1; Paronyan, G. M. 1; Knyazyan, A. V. 2; Mikayelyan, G. A. 1; Farmanyan, S. V. 1; Hovhannisyan, L. R. 1; Nikoghosyan, E. H. 1; Abrahamyan, H. V. 1; Andreasyan, H. R. 1; Azatyan, N. M. 1; Khachatryan, K. G. 1; Kostandyan, G. R. 1; Vardanyan, A. V. 1
A review on Byurakan Astrophysical Observatory (BAO) Plate Archive and Armenian Virtual Observatory (ArVO) projects is given. BAO Plate Archive consists of 37,500 photographic plates and films, obtained with 2.6m telescope, 1m and 0.5m Schmidt telescopes and other smaller ones during 1947-1991. The famous Markarian Survey (or the First Byurakan Survey, FBS) 2000 plates were digitized in 2002-2005 and the Digitized FBS (DFBS, www.aras.am/Dfbs/dfbs.html) was created. New science projects have been conducted based on this low-dispersion spectroscopic material. Several other smaller digitization projects have been carried out as well, such as part of Second Byurakan Survey (SBS) plates, photographic chain plates in Coma, where the blazar ON 231 is located and 2.6m film spectra of FBS Blue Stellar Objects. However, most of the plates and films are not digitized. In 2015, we have started a project on the whole BAO Plate Archive digitization, creation of electronic database and its scientific usage. Armenian Virtual Observatory (ArVO, www.aras.am/Arvo/arvo.htm) database will accommodate all new data. The project runs in collaboration with the Armenian Institute of Informatics and Automation Problems (IIAP) and will continue during 3 years in 2015-2017. The final result will be an Electronic Database and online Interactive Sky map to be used for further research projects. ArVO will provide all standards and tools for efficient usage of the scientific output and its integration in international databases.
Buša, Ján; Hayryan, Shura; Wu, Ming-Chya; Buša, Ján; Hu, Chin-Kun
Introduction of Graphical Processing Units (GPUs) and computing using GPUs in recent years opened possibilities for simple parallelization of programs. In this update, we present the modernized version of program ARVO [J. Buša, J. Dzurina, E. Hayryan, S. Hayryan, C.-K. Hu, J. Plavka, I. Pokorný, J. Skivánek, M.-C. Wu, Comput. Phys. Comm. 165 (2005) 59]. The whole package has been rewritten in the C language and parallelized using OpenCL. Some new tricks have been added to the algorithm in order to save memory much needed for efficient usage of graphical cards. A new tool called ‘input_structure’ was added for conversion of pdb files into files suitable for work with the C and OpenCL version of ARVO.
The 2010 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO), held in Fort Lauderdale, FL, USA, included topics covering new therapeutic developments in the field of eye and vision research. This conference report highlights selected presentations on the development of FOV-2304 (Fovea Pharmaceuticals SA) for the potential treatment of diabetic macular edema; PHA-666859 (Pfizer Inc) for diabetic retinopathy; GTx-878 (GTx Inc) and FCFD-4514S (Genentech Inc) for age-related macular degeneration; SYL-040012 (Sylentis Sau) for ocular hypertension associated with open-angle glaucoma; PEG-PLA-TNP-470 (Harvard Medical School) for ocular neovascularization; recombinant galectin-3 (Senju Pharmaceutical Co Ltd) for corneal injury; and CellBead Neuro (CellMed Inc) for neurological trauma and neurodegeneration.
The 2010 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO), held in Fort Lauderdale, FL, USA, included topics covering new therapeutic developments in the field of eye and vision research. This conference report highlights selected presentations on the development of OT-440 (Othera Pharmaceuticals Inc) for the potential treatment of glaucoma, an extended-release implant of brimonidine (pSivida Corp) for ocular hypertension, AR-12286 (Aerie Pharmaceuticals Inc) for ocular hypertension or glaucoma, AC-8 (Calmune Corp/RiboVax Biotechnologies SA) for ocular diseases following HSV infection, and fidarestat (Sanwa Kagaku Kenkyusho Co Ltd) and the recombinant proteins NOV and NOVCter (INSERM/University Rene Descartes) for corneal neovascularization.
Mickaelian, A. M.; Astsatryan, H. V.; Knyazyan, A. V.; Magakian, T. Yu.; Mikayelyan, G. A.; Erastova, L. K.; Hovhannisyan, L. R.; Sargsyan, L. A.; Sinamyan, P. K.
Armenian Virtual Observatory (ArVO, www.aras.am/Arvo/arvo.htm) was created 10 years ago, in 2005, when after the accomplishment of the Digitized First Byurakan Survey (DFBS, www.aras.am/Dfbs/dfbs.html) we had enough resources to run a VO project and contribute in the International Virtual Observatory Alliance (IVOA, www.ivoa.net). ArVO is a project of Byurakan Astrophysical Observatory (BAO) aimed at construction of a modern system for data archiving, extraction, acquisition, reduction, use and publication. ArVO technical and research projects include Global Spectroscopic Database, which is being built based on DFBS. Quick optical identification of radio, IR or X-ray sources will be possible by plotting their positions in the DFBS or other spectroscopic plate and matching all available data. Accomplishment of new projects by combining data is so important that the International Council of Scientific Unions (ICSU) recently created World Data System (WDS, www.icsu-wds.org/) for unifying data coming from all science areas, and BAO has also joined it due to DFBS and ArVO projects.
Knyazyan, A. V.; Astsatryan, H. V.; Mickaelian, A. M.
The main aim of this article is to introduce the data management and services of the Armenian Virtual Observatory (ArVO), which consists of user friendly data management mechanisms, a new and productive cross-correlation service, and data sharing API based on international standards and protocols.
Kim, Stephen J.
The ARVO 2014 minisymposium on “Novel Approaches for Retinal Drug and Gene Delivery” was held on May 6, 2014 in Orlando, FL. The main intent of the symposium was to review recent advances in retinal drug and gene delivery with specific emphasis on novel approaches that address current limitations and have the potential to translate into clinical practice. The symposium was sponsored by Translational Vision Science and Technology. PMID:25346872
The Byurakan Astrophysical Observatory (BAO, Armenia, http://www.bao.am) are among the candidate IAU Regional Nodes for Astronomy for Development activities. It is one of the main astronomical centers of the former Soviet Union and the Middle East region. At present there are 48 qualified researchers at BAO, including six Doctors of Science and 30 PhDs. Five important observational instruments are installed at BAO, the larger ones being 2.6m Cassegrain (ZTA-2.6) and 1m Schmidt (the one that provided the famous Markarian survey). BAO is regarded as a national scientific-educational center, where a number of activities are being organized, such as: international conferences (4 IAU symposia and 1 IAU colloquium, JENAM-2007, etc.), small workshops and discussions, international summer schools (1987, 2006, 2008 and 2010), and Olympiads. BAO collaborates with scientists from many countries. The Armenian Astronomical Society (ArAS, http://www.aras.am/) is an NGO founded in 2001; it has 93 members and it is rather active in the organization of educational, amateur, popular, promotional and other matters. The Armenian Virtual Observatory (ArVO, http://www.aras.am/Arvo/arvo.htm) is one of the 17 national VO projects forming the International Virtual Observatories Alliance (IVOA) and is the only VO project in the region serving also for educational purposes. A number of activities are planned, such as management, coordination and evaluation of the IAU programs in the area of development and education, establishment of the new IAU endowed lectureship program and organization of seminars and public lectures, coordination and initiation of fundraising activities for astronomy development, organization of regional scientific symposia, conferences and workshops, support to Galileo Teacher Training Program (GTTP), production/publication of educational and promotional materials, etc.
Beutter, B. R.; Mulligan, J. B.; Stone, L. S.; Hargens, Alan R. (Technical Monitor)
We have shown that moving a plaid in an asymmetric window biases the perceived direction of motion (Beutter, Mulligan & Stone, ARVO 1994). We now explore whether these biased motion signals might also drive the smooth eye-movement response by comparing the perceived and tracked directions. The human smooth oculomotor response to moving plaids appears to be driven by the perceived rather than the veridical direction of motion. This suggests that human motion perception and smooth eye movements share underlying neural motion-processing substrates as has already been shown to be true for monkeys.
Wang, Ling; Lu, Luo
Purpose To define the role of molecular interaction between the UV-induced JNK (c-Jun N-terminal kinase) cascade and corneal epithelial cell apoptosis and protection against apoptosis by caffeine. Methods Rabbit and human corneal epithelial cells were cultured in DMEM/F12 medium containing 10% FBS and 5 μg/mL insulin at 37°C in 5% CO2. DNA fragmentation and ethidium bromide/acridine orange (EB/AO) nuclear staining were performed to detect cell death. Western blot, immunoprecipitation, and kinase assays were used to measure UV-induced mitogen-activated protein (MAP) kinase activity. Results UV irradiation–induced apoptosis through apoptosis signal-regulating kinase 1 (ASK1) and MAKK4 (SEK1) upstream from JNK was caffeine sensitive. Caffeine (1,3,7-trimethylxanthine), an agent that is one of the most popular additions to food consumed in the world and a potential enhancer of chemotherapy, effectively protected corneal epithelial cells against apoptosis by its specific effect on the JNK cascade. Theophylline (1,3-dimethylxanthine) exhibited an effect similar to that of caffeine on prevention of UV irradiation–induced apoptosis. However, alterations of either intracellular cAMP or Ca2+ levels did not alter the effect of caffeine on the JNK signaling pathway. In addition, the blockade of PI3K-like kinases by wortmannin had no impact on the protective effect of caffeine against UV irradiation–induced apoptosis, suggesting that the protective effect of caffeine acts through a specific mechanism involving UV irradiation–induced activation of ASK1 and SEK1. In contrast, caffeine had no effects on melphalan-, hyperosmotic stress–, or IL-1 β-induced activation of the JNK signaling pathway in these cells. Conclusions UV irradiation stress–induced activation of the ASK1-SEK1-JNK signaling pathway leading to apoptosis is a caffeine-sensitive process, and caffeine, as a multifunctional agent in cells, can specifically interact with the pathway to protect against
Battu, Rajani; Dabir, Supriya; Khanna, Anjani; Kumar, Anupama Kiran; Roy, Abhijit Sinha
Adaptive optics is a relatively new tool that is available to ophthalmologists for study of cellular level details. In addition to the axial resolution provided by the spectral-domain optical coherence tomography, adaptive optics provides an excellent lateral resolution, enabling visualization of the photoreceptors, blood vessels and details of the optic nerve head. We attempt a mini review of the current role of adaptive optics in retinal imaging. PubMed search was performed with key words Adaptive optics OR Retina OR Retinal imaging. Conference abstracts were searched from the Association for Research in Vision and Ophthalmology (ARVO) and American Academy of Ophthalmology (AAO) meetings. In total, 261 relevant publications and 389 conference abstracts were identified.
Feke, G T
The theory underlying the development of laser Doppler instrumentation for the measurement of retinal blood flow is framed in terms of (a) the enunciation of the Doppler principle; (b) the invention of the laser; and (c) the invention of the technique known as optical mixing spectroscopy. The features of the instrumentation, beginning with the first prototype in 1972 and culminating with the introduction of the Canon Laser Blood Flowmeter in 1998 are presented in detail. Results from seven separate studies reporting on the reproducibility of retinal blood flow measurements using the Canon instrument, as well as a review of 12 separate presentations made at the 2004 annual meeting of the Association for Research in Vision and Ophthalmology (ARVO) using the Canon instrument in studies involving retinal circulatory physiology and associated clinical research are also presented. PMID:17265797
Battu, Rajani; Dabir, Supriya; Khanna, Anjani; Kumar, Anupama Kiran; Roy, Abhijit Sinha
Adaptive optics is a relatively new tool that is available to ophthalmologists for study of cellular level details. In addition to the axial resolution provided by the spectral-domain optical coherence tomography, adaptive optics provides an excellent lateral resolution, enabling visualization of the photoreceptors, blood vessels and details of the optic nerve head. We attempt a mini review of the current role of adaptive optics in retinal imaging. PubMed search was performed with key words Adaptive optics OR Retina OR Retinal imaging. Conference abstracts were searched from the Association for Research in Vision and Ophthalmology (ARVO) and American Academy of Ophthalmology (AAO) meetings. In total, 261 relevant publications and 389 conference abstracts were identified. PMID:24492503
Mulligan, Jeffrey B.; Null, Cynthia H. (Technical Monitor)
In the analysis of visual motion, local features such as orientation are analyzed early in the cortical processing stream (V1), while integration across orientation and space is thought to occur in higher cortical areas such as MT, MST, etc. If all areas provide inputs to eye movement control centers, we would expect that local properties would drive eye movements with relatively short latencies, while global properties would require longer latencies. When such latencies are observed, they can provide information about when (and where?) various stimulus properties are analyzed. To this end, a stimulus was employed in which local and global properties determining perceived direction-of-motion could be manipulated independently: an elliptical Gabor patch with a drifting carrier, with variable orientation of the carrier grating and the contrast window. We have previously demonstrated that the directional percepts evoked by this stimulus vary between the "grating direction" (the normal to the grating's orientation) and the "window direction" (ARVO 91, 94), and that similar effects can be observed in reflexive eye movements (ARVO 95). Subjects viewed such a stimulus while attempting to maintain steady fixation on the center of the pattern, and the small reflexive eye movements ("stare OKN") were recorded. In the middle of the trial, the orientation of either the grating or the window was rotated smoothly by 30 degrees. Responses to the shift of both grating orientation and window orientation are seen in the average OKN slow phase velocity. Grating rotations produce a rapid OKN rotation to the grating direction (100 ms latency, 300 ms time constant), followed by a slower rebound to the steady state perceived direction midway between the grating and window directions. Window rotations, on the other hand, evoke a slower response (200 ms latency, 500 ms time constant). The results demonstrate multiple cortical inputs to eye movement control: a taste early input driven by
Background The inclusion of randomized controlled trials (RCTs) reported in conference abstracts in systematic reviews is controversial, partly because study design information and risk of bias is often not fully reported in the abstract. The Association for Research in Vision and Ophthalmology (ARVO) requires trial registration of abstracts submitted for their annual conference as of 2007. Our goal was to assess the feasibility of obtaining study design information critical to systematic reviews, but not typically included in conference abstracts, from the trial registration record. Methods We reviewed all conference abstracts presented at the ARVO meetings from 2007 through 2009, and identified 496 RCTs; 154 had a single matching registration record in ClinicalTrials.gov. Two individuals independently extracted information from the abstract and the ClinicalTrials.gov record, including study design, sample size, inclusion criteria, masking, interventions, outcomes, funder, and investigator name and contact information. Discrepancies were resolved by consensus. We assessed the frequencies of reporting variables appearing in the abstract and the trial register and assessed agreement of information reported in both sources. Results We found a substantial amount of study design information in the ClinicalTrials.gov record that was unavailable in the corresponding conference abstract, including eligibility criteria associated with gender (83%; 128/154); masking or blinding of study participants (53%, 82/154), persons administering treatment (30%, 46/154), and persons measuring the outcomes (40%, 61/154)); and number of study centers (58%; 90/154). Only 34% (52/154) of abstracts explicitly described a primary outcome, but a primary outcome was included in the “Primary Outcome” field in the ClinicalTrials.gov record for 82% (126/154) of studies. One or more study interventions were reported in each abstract, but agreed exactly with those reported in Clinical
Mickaelian, A. M.; Abrahamyan, H. V.; Andreasyan, H. R.; Azatyan, N. M.; Farmanyan, S. V.; Gigoyan, K. S.; Gyulzadyan, M. V.; Khachatryan, K. G.; Knyazyan, A. V.; Kostandyan, G. R.; Mikayelyan, G. A.; Nikoghosyan, E. H.; Paronyan, G. M.; Vardanyan, A. V.
The most important part of the astronomical observational heritage are astronomical plate archives created on the basis of numerous observations at many observatories. Byurakan Astrophysical Observatory (BAO) plate archive consists of 37,000 photographic plates and films, obtained at 2.6m telescope, 1m and 0.5m Schmidt type and other smaller telescopes during 1947-1991. In 2002-2005, the famous Markarian Survey (also called First Byurakan Survey, FBS) 1874 plates were digitized and the Digitized FBS (DFBS) was created. New science projects have been conducted based on these low-dispersion spectroscopic material. A large project on the whole BAO Plate Archive digitization, creation of electronic database and its scientific usage was started in 2015. A Science Program Board is created to evaluate the observing material, to investigate new possibilities and to propose new projects based on the combined usage of these observations together with other world databases. The Executing Team consists of 11 astronomers and 2 computer scientists and will use 2 EPSON Perfection V750 Pro scanners for the digitization, as well as Armenian Virtual Observatory (ArVO) database will be used to accommodate all new data. The project will run during 3 years in 2015-2017 and the final result will be an electronic database and online interactive sky map to be used for further research projects, mainly including high proper motion stars, variable objects and Solar System bodies.
Mickaelian, Areg M.
Astronomical plate archives created on the basis of numerous observations at many observatories are important part of the astronomical heritage. Byurakan Astrophysical Observatory (BAO) plate archive consists of 37,500 photographic plates and films, obtained at 2.6m telescope, 1m and 0.5m Schmidt telescopes and other smaller ones during 1947-1991. In 2002-2005, the famous Markarian Survey (First Byurakan Survey, FBS) 2000 plates were digitized and the Digitized FBS (DFBS, http://www.aras.am/Dfbs/dfbs.html) was created. New science projects have been conducted based on these low-dispersion spectroscopic material. In 2015, we have started a project on the whole BAO Plate Archive digitization, creation of electronic database and its scientific usage. A Science Program Board is created to evaluate the observing material, to investigate new possibilities and to propose new projects based on the combined usage of these observations together with other world databases. The Executing Team consists of 9 astronomers and 3 computer scientists and will use 2 EPSON Perfection V750 Pro scanners for the digitization, as well as Armenian Virtual Observatory (ArVO) database to accommodate all new data. The project will run during 3 years in 2015-2017 and the final result will be an electronic database and online interactive sky map to be used for further research projects.
van de Put, Mathijs A. J.; Croonen, Danna; Nolte, Ilja M.; Japing, Wouter J.; Hooymans, Johanna M. M.; Los, Leonoor I.
Purpose To determine which factors affect the recovery of visual function in macula off rhegmatogenous retinal detachment (RRD). Methods In a prospective study of forty-five patients with a primary macula-off RRD of 24 hours to 6 weeks duration, the height of the macular detachment was determined by ultrasonography. At 12 months postoperatively, best corrected visual acuity (BCVA), contrast acuity, and color confusion indexes (CCI) were obtained. Results Macular detachment was present for 2–32 (median 7) days before repair. A shorter duration of macular detachment was correlated with a better CCI saturé (p = 0.0026) and lower LogMAR BCVA (better Snellen visual acuity)(p = 0.012). Also, a smaller height of macular detachment was correlated with a lower LogMAR BCVA (p = 0.0034). A younger age and lower pre-operative LogMAR BCVA at presentation were both correlated with better postoperative contrast acuity in the total group (age: p = 1.7×10−4 and pre-operative LogMAR BCVA: p = 0.0034). Conclusion Functional recovery after macula-off RRD is affected by the duration and the height of the macular detachment. Recovery of contrast acuity is also affected by age and BCVA at presentation. Meeting presentation ARVO annual meeting 2013, May 7, Seattle, Washington, United States of America. Trial registration: trialregister.nl NTR839 PMID:24927502
Mickaelian, A. M.
Astronomy in Armenia was popular since ancient times. There are signs of astronomical observations coming from a few thousands years ago. Two ancient observatories, Karahunge and Metzamor are especially well known. Karahunge is the Armenian twin of the Stonehenge and is even older. However, there is no proper attention from the state authorities and efforts are needed for preservation of such historical-astronomical monuments. The Byurakan Astrophysical Observatory (BAO) is the modern famous Armenian observatory founded in 1946 by the outstanding scientist Victor Ambartsumian. It was one of the world astronomical centres in 1950-s to 1970-s, and at present is the largest observatory in the Middle East area. As the ancient astronomical sites, Byurakan also needs a proper attitude from the state authorities and corresponding international organizations to preserve its values and importance for the present and future astronomical activities in the region, including its rich observational archive, telescopes, and human resources. Despite all the difficulties, the Armenian astronomers keep high international level of research and display various activities organizing international meetings and schools, preparing new young generation for the future research. The Armenian Astronomical Society (ArAS) is an affiliated member of EAS. Armenia has its Virtual Observatory project (ArVO) as well. The next Joint European and National Astronomy Meeting (JENAM-2007) will be held in Yerevan, Armenia, in August 2007. There are plans to organize astronomical tours to Armenia for making observations from various sites, including the ancient observatories. The future of astronomy in Armenia strongly depends on all of this activities and the proper attention both from state authorities and society.
Mickaelian, Areg; Kochiashvili, Nino; Astsatryan, Hrach; Harutyunian, Haik; Magakyan, Tigran; Chargeishvili, Ketevan; Natsvlishvili, Rezo; Kukhianidze, Vasil; Ramishvili, Giorgi; Sargsyan, Lusine; Sinamyan, Parandzem; Kochiashvili, Ia; Mikayelyan, Gor
The Armenian-Georgian Virtual Observatory (ArGVO) project is the first initiative in the world to create a regional VO infrastructure based on national VO projects and regional Grid. The Byurakan and Abastumani Astrophysical Observatories are scientific partners since 1946, after establishment of the Byurakan observatory . The Armenian VO project (ArVO) is being developed since 2005 and is a part of the International Virtual Observatory Alliance (IVOA). It is based on the Digitized First Byurakan Survey (DFBS, the digitized version of famous Markarian survey) and other Armenian archival data. Similarly, the Georgian VO will be created to serve as a research environment to utilize the digitized Georgian plate archives. Therefore, one of the main goals for creation of the regional VO is the digitization of large amounts of plates preserved at the plate stacks of these two observatories. The total amount of plates is more than 100,000 units. Observational programs of high importance have been selected and some 3000 plates will be digitized during the next two years; the priority is being defined by the usefulness of the material for future science projects, like search for new objects, optical identifications of radio, IR, and X-ray sources, study of variability and proper motions, etc. Having the digitized material in VO standards, a VO database through the regional Grid infrastructure will be active. This partnership is being carried out in the framework of the ISTC project A-1606 "Development of Armenian-Georgian Grid Infrastructure and Applications in the Fields of High Energy Physics, Astrophysics and Quantum Physics".
We have used ARVO developed by us to find that the ratio of volume and surface area of proteins in Protein Data Bank distributed in a very narrow region . Such result is useful for the determination of protein 3D structures. It has been widely known that a spin glass model can be used to understand the slow relaxation behavior of a glass at low temperatures . We have used molecular dynamics and simple models of polymer chains to study relaxation and aggregation of proteins under various conditions and found that polymer chains with neighboring monomers connected by rigid bonds can relax very slowly and show glassy behavior . We have also found that native collagen fibrils show glassy behavior at room temperatures . The results of  and  about the glassy behavior of polymers or proteins are useful for understanding the mechanism for a biological system to maintain in a non-equilibrium state, including the ancient seed , which can maintain in a non-equilibrium state for a very long time. (1) M.-C. Wu, M. S. Li, W.-J. Ma, M. Kouza, and C.-K. Hu, EPL, in press (2011); (2) C. Dasgupta, S.-K. Ma, and C.-K. Hu. Phys. Rev. B 20, 3837-3849 (1979); (3) W.-J. Ma and C.-K. Hu, J. Phys. Soc. Japan 79, 024005, 024006, 054001, and 104002 (2010), C.-K. Hu and W.-J. Ma, Prog. Theor. Phys. Supp. 184, 369 (2010); S. G. Gevorkian, A. E. Allahverdyan, D. S. Gevorgyan and C.-K. Hu, EPL 95, 23001 (2011); S. Sallon, et al. Science 320, 1464 (2008).
Barghout-Stein, Lauren; Tyler, Christopher W.; Klein, Stanley A.
noise that intrudes on the detecting mechanism from neighboring mechanisms. A detailed review of this debate is provided by the paper by Klein et al., 3016-02 in this Proceedings. Threshold elevation functions that show the relationship between mask spatial frequency and masking magnitude cannot illuminate this debate, as we demonstrated at ARVO (1994). For that study, we generated threshold elevation functions (the ratio of unmasked versus masked target threshold) for multi-channel systems using computational models that invoked either divisive inhibition, a set of transducer nonlinearities or multiplicative noise. Threshold elevation functions were indistinguishable when each masking process was assumed to have similar strength. These results led us to design the experiment presented here, which attempts to compare the effects of two of these masking processes, lateral divisive inhibition and nonlinear transducer compression.
Kumpulainen, S M; Heinonen, K; Salonen, M K; Andersson, S; Wolke, D; Kajantie, E; Eriksson, J G; Raikkonen, K
Background: Childhood cognitive ability has been identified as a novel risk factor for adulthood overweight and obesity as assessed by adult body mass index (BMI). BMI does not, however, distinguish fat-free and metabolically harmful fat tissue. Hence, we examined the associations between childhood cognitive abilities and body fat percentage (BF%) in young adulthood. Methods: Participants of the Arvo Ylppö Longitudinal Study (n=816) underwent tests of general reasoning, visuomotor integration, verbal competence and language comprehension (M=100; s.d.=15) at the age of 56 months. At the age of 25 years, they underwent a clinical examination, including measurements of BF% by the InBody 3.0 eight-polar tactile electrode system, weight and height from which BMI (kg m−2) was calculated and waist circumference (cm). Results: After adjustments for sex, age and BMI-for-age s.d. score at 56 months, lower general reasoning and visuomotor integration in childhood predicted higher BMI (kg m−2) increase per s.d. unit decrease in cognitive ability (−0.32, 95% confidence interval −0.60,−0.05; −0.45, −0.75,−0.14, respectively) and waist circumference (cm) increase per s.d. unit decrease in cognitive ability (−0.84, −1.56,−0.11; −1.07,−1.88,−0.26, respectively) in adulthood. In addition, lower visuomotor integration predicted higher BF% per s.d. unit decrease in cognitive ability (−0.62,−1.14,−0.09). Associations between general reasoning and BMI/waist were attenuated when adjusted for smoking, alcohol consumption, intake of fruits and vegetables and physical activity in adulthood, and all associations, except for visuomotor integration and BMI, were attenuated when adjusted for parental and/or own attained education and/or birth weight. Conclusions: Of the measured childhood cognitive abilities, only lower visuomotor integration was associated with BF% in adulthood. This challenges the view that cognitive ability, at least when measured in
Pogacsas, Gyorgy; Juhász, Györgyi; Mádl-Szőnyi, Judit; Simon, Szilvia; Lukács, Szilveszter; Csizmeg, János
Africa-Europe convergence vector. Pliocene-Quaternary was characterised by 1-5 km left lateral wrenching along the Mid-Hungarian Mobile Belt. Based on high resolution seismic measurements on the Danube river Toth (2003) supposed an even more recent activity along the Paks-Szolnok wrench fault zone. The supposed late Quaternary activity of the Mid-Hungarian Mobile Belt is supported by recent hydrogeologic investigations. According to Mádl-Szőnyi et al (2005) and Simon et al (in press) from the Pre-Neogene basement originates an ascending overpressured highly saline water flow regime. Deep ascending water rises near to the surface, intercepting the aquifer and aquitard layers along conductive strike slipe faults of the Mid-Hungarian Mobile Belt and mixing with shallower groundwater. Acknowledgements The research work was supported by the Hungarian National Research Fund (OTKA 035168, T 047159). References Detzky Lőrinc K. (1997) Detailed tectonic study of the Western edge of the Szolnok flysch zone using seismic and well data. Thesis Candidate of Science. Hungarian Academy of Science. p. 121. Grow J. A., R. E. Mattick, A. Bérczi-Makk, Cs. Péró, D. Hajdú, Gy. Pogácsás, P. Várnai, E. Varga, (1994) Structure of the Békés basin inferred from seismic reflection, well and gravity data. in Teleki P., J. Kókai, R.E. Mattick eds. Basin analysis in petroleum exploration, a case study from the Békés basin, Hungary. Kluwer Academic Publisher, Dordrecht, Netherlands, p. 1-38. Juhász, Gy., Pogácsás Gy., Magyar I. (2007) A giant canyon system incised into the Late-Neogene (pannonian s.l.) sediments? (in Hungarian Óriáskanyon-rendszer szeli át a pannóniai üledékeket? Földtani Közlöny (Bulletin of the Geological Society of Hungary)137/3. 307-326. Mádlné Szőnyi J. Simon Sz. Tóth J. Pogácsás Gy. (2005) Interrelationship between surface and subsurface waters at the Kelemen-szék and Kolon lakes, Duna-Tisza Interfluve, Hungary (in Hungarian Felszíni és felsz
Nõmmiste, Ergo; Kirm, Marco; Plank, Toomas
oral, and 5 commercial talks were delivered and more than 200 posters were presented. In the framework of conference more than 20 papers were submitted to a topical issue of Physica Scripta. Based on the work presented at the conference, 62 articles are included in this volume of IOP Conference Series: Materials Science and Engineering. Additional information about FM&NT-2013 is available at its homepage http://fmnt.ut.ee/. The Organizing Committee would like to thank all the speakers, contributors, session chairs, referees and other involved staff for their efforts in making FM&NT-2013 successful. Special thanks for their hard work dealing with the conference papers goes to the Guest Editors: Professor Mikhail Brik, Dr Svetlana Zazubovits, Dr Arvo Kikas, Dr Rainer Pärna. The Organizing Committee hopes that Conference gave participants good insight into recent developments in nanotechnology, sustainable energetics, processing and modelling of multifunctional materials and research done using synchrotron radiation or other novel light sources. We sincerely hope that conference has provided support for the sharing of information and has brought together many young and experienced scientists from different fields, leading to fruitful discussions. We hope that all participants had good and memorable time in Tartu. On the behalf of organising committee Professor Ergo Nõmmiste Dr Marco Kirm Dr Toomas Plank The PDF also contains lists of the committees, the conference photograph and the sponsor's logos.