Sample records for assembly building main

  1. 34. SOUTHWEST CORNER OF BUILDING 233 (MISSILE ASSEMBLY SHOP) IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    34. SOUTHWEST CORNER OF BUILDING 233 (MISSILE ASSEMBLY SHOP) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  2. DETAIL VIEW ON THE MAIN ASSEMBLY LEVEL OF ELEVATOR SHOWING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW ON THE MAIN ASSEMBLY LEVEL OF ELEVATOR SHOWING THE DOUBLED COLUMN FOR THE BUILDING EXPANSION JOINT AT COLUMN LINE AA-18. - Offutt Air Force Base, Glenn L. Martin-Nebraska Bomber Plant, Building D, Peacekeeper Drive, Bellevue, Sarpy County, NE

  3. 36. CONTEXT VIEW LOOKING SOUTHWEST OF BUILDING 233 (MISSLE ASSEMBLY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    36. CONTEXT VIEW LOOKING SOUTHWEST OF BUILDING 233 (MISSLE ASSEMBLY SHOP) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  4. 35. EAST FRONT ELEVATION OF BUILDING 233 (MISSLE ASSEMBLY SHOP) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    35. EAST FRONT ELEVATION OF BUILDING 233 (MISSLE ASSEMBLY SHOP) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  5. Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. Kennedy Space Center, Florida. File Number 79K05424, Seelye Stevenson Value & Knecht, March 1975. HIGH BAY 3, EXTENSIBLE WORK PLATFORM ‘D’, MAIN FLOOR PLAN, ARCHITECTURAL. Sheet 39 of 207 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  6. Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. Kennedy Space Center, Florida. File Number 79K05424, Seelye Stevenson Value & Knecht, March 1975. HIGH BAY 3, EXTENSIBLE WORK PLATFORM ‘E’, MAIN FLOOR PLAN, ARCHITECTURAL. Sheet 23 of 207 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  7. Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. Kennedy Space Center, Florida. File Number 79K05424, Seelye Stevenson Value & Knecht, March 1975. HIGH BAY 3, EXTENSIBLE WORK PLATFORM ‘B’, MAIN FLOOR PLAN, ARCHITECTURAL. Sheet 30 of 207 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  8. Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. Kennedy Space Center, Florida. File Number 79K05424, Seelye Stevenson Value & Knecht, March 1975. HIGH BAY 3, EXTENSIBLE WORK PLATFORM ‘C’, MAIN FLOOR PLAN, ARCHITECTURAL. Sheet 16 of 207 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  9. 26. SOUTH CORNER OF BUILDING 227 (FIRE STATION) IN ASSEMBLY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. SOUTH CORNER OF BUILDING 227 (FIRE STATION) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  10. 32. NORTHEAST CORNER OF BUILDING 232 (MINE SHOP) IN ASSEMBLY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    32. NORTHEAST CORNER OF BUILDING 232 (MINE SHOP) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  11. 33. SOUTHWEST CORNER OF BUILDING 232 (MINE SHOP) IN ASSEMBLY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    33. SOUTHWEST CORNER OF BUILDING 232 (MINE SHOP) IN ASSEMBLY AREA WITH INDEPENDENT BLAST WALL AT LEFT. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  12. DETAIL VIEW ABOVE THE MAIN ASSEMBLY LEVEL SHOWING HOIST AT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW ABOVE THE MAIN ASSEMBLY LEVEL SHOWING HOIST AT COLUMN LINE U-6 USED FOR LIFTING WING COMPONENTS FROM THE WING ASSEMBLY ANNEX TO THE B-29 PRODUCTION LINE. - Offutt Air Force Base, Glenn L. Martin-Nebraska Bomber Plant, Building D, Peacekeeper Drive, Bellevue, Sarpy County, NE

  13. 133. Photocopy of photograph, 1915 (Chrysler) MAIN BUILDING #1, SECOND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    133. Photocopy of photograph, 1915 (Chrysler) MAIN BUILDING #1, SECOND FLOOR CHASSIS ASSEMBLY LINE, VIEW SOUTH, 1980 - Dodge Brothers Motor Car Company Plant, Between Joseph Campau & Conant Avenues, Hamtramck, MI

  14. 23. SOUTHWEST CORNER OF BUILDING 220 (ENTRY CONTROL BUILDING) IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. SOUTHWEST CORNER OF BUILDING 220 (ENTRY CONTROL BUILDING) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  15. 22. NORTH ELEVATION OF BUILDING 220 (ENTRY CONTROL BUILDING) IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. NORTH ELEVATION OF BUILDING 220 (ENTRY CONTROL BUILDING) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  16. 40. NORTHWEST FRONT ELEVATION OF BUILDING 269 (PAINT BUILDING) IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    40. NORTHWEST FRONT ELEVATION OF BUILDING 269 (PAINT BUILDING) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  17. 42. CONTEXT VIEW LOOKING WEST OF BUILDING 269 (PAINT BUILDING) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    42. CONTEXT VIEW LOOKING WEST OF BUILDING 269 (PAINT BUILDING) IN ASSEMBLY AREA SHOWING BUILDING 272 (STORAGE STRUCTURE A-2) IN BACKGROUND. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  18. 2. VIEW TO THE SOUTHWEST OF THE MAIN EMAD BUILDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. VIEW TO THE SOUTHWEST OF THE MAIN E-MAD BUILDING WITH THE COLD BAY ON THE EAST (LEFT) AND THE HOT BAY ON THE WEST (RIGHT). - Nevada Test Site, Engine Maintenance Assembly & Disassembly Facility, Area 25, Jackass Flats, Mercury, Nye County, NV

  19. 41. CONTEXT VIEW LOOKING EAST OF BUILDING 269 (PAINT BUILDING) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    41. CONTEXT VIEW LOOKING EAST OF BUILDING 269 (PAINT BUILDING) IN ASSEMBLY AREA SHOWING ROW OF IGLOOS IN BACKGROUND. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  20. DETAIL VIEW ON THE MAIN ASSEMBLY LEVEL OF A LADDER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW ON THE MAIN ASSEMBLY LEVEL OF A LADDER TO THE CATWALK AT COLUMN LINE AA-28 SHOWING VERTICAL MECHANICAL DUCT, RETURN AIR FLOOR GRILLE, STEEL INDUSTRIAL SASH WINDOWS AND CROSS BRACING OF SOUTH WALL. - Offutt Air Force Base, Glenn L. Martin-Nebraska Bomber Plant, Building D, Peacekeeper Drive, Bellevue, Sarpy County, NE

  1. 28. CONTEXT VIEW OF BUILDING 229 (ELECTRIC POWER STATION) IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    28. CONTEXT VIEW OF BUILDING 229 (ELECTRIC POWER STATION) IN ASSEMBLY AREA WITH BUILDING 227 (FIRE STATION) IMMEDIATELY TO THE LEFT. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  2. 31. SOUTH FRONT ELEVATION OF BUILDING 232 (MINE SHOP) IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    31. SOUTH FRONT ELEVATION OF BUILDING 232 (MINE SHOP) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  3. 25. SOUTHEAST FRONT ELEVATION OF BUILDING 227 (FIRE STATION) IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    25. SOUTHEAST FRONT ELEVATION OF BUILDING 227 (FIRE STATION) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  4. 30. EAST CORNER OF BUILDING 229 (ELECTRIC POWER STATION) IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    30. EAST CORNER OF BUILDING 229 (ELECTRIC POWER STATION) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  5. 27. CONTEXT VIEW LOOKING EAST SHOWING BUILDING 227 (FIRE STATION) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    27. CONTEXT VIEW LOOKING EAST SHOWING BUILDING 227 (FIRE STATION) AT RIGHT AND BUILDING 229 (ELECTRIC POWER STATION) AT LEFT IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  6. 39. DOOR DETAIL OF BUILDING 235 (PAINT AND REPAIR SHOP) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    39. DOOR DETAIL OF BUILDING 235 (PAINT AND REPAIR SHOP) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  7. 37. NORTH ELEVATION OF BUILDING 235 (PAINT AND REPAIR SHOP) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    37. NORTH ELEVATION OF BUILDING 235 (PAINT AND REPAIR SHOP) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  8. 29. SOUTHEAST FRONT ELEVATION OF BUILDING 229 (ELECTRIC POWER STATION) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    29. SOUTHEAST FRONT ELEVATION OF BUILDING 229 (ELECTRIC POWER STATION) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  9. 19. SOUTH FRONT ELEVATION OF BUILDING 216 (AMMUNITION MAINTENANCE SHOP) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. SOUTH FRONT ELEVATION OF BUILDING 216 (AMMUNITION MAINTENANCE SHOP) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  10. Deconstructing Building Blocks: Preschoolers' Spatial Assembly Performance Relates to Early Mathematical Skills

    ERIC Educational Resources Information Center

    Verdine, Brian N.; Golinkoff, Roberta M.; Hirsh-Pasek, Kathryn; Newcombe, Nora S.; Filipowicz, Andrew T.; Chang, Alicia

    2014-01-01

    This study focuses on three main goals: First, 3-year-olds' spatial assembly skills are probed using interlocking block constructions (N = 102). A detailed scoring scheme provides insight into early spatial processing and offers information beyond a basic accuracy score. Second, the relation of spatial assembly to early mathematical skills…

  11. 38. CONTEXT VIEW LOOKING WEST OF BUILDING 235 (PAINT AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    38. CONTEXT VIEW LOOKING WEST OF BUILDING 235 (PAINT AND REPAIR SHOP) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  12. VIEW OF BUILDING NO. 77710A, LOOKING WEST. LABORATORY WING AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF BUILDING NO. 777-10A, LOOKING WEST. LABORATORY WING AND MAIN ENTRANCE ON RIGHT; MULTISTORY REACTOR WING IN LEFT BACKGROUND - Physics Assembly Laboratory, Area A/M, Savannah River Site, Aiken, Aiken County, SC

  13. 45. CONTEXT VIEW LOOKING SOUTH OF BUILDING 272 (STORAGE STRUCTURE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    45. CONTEXT VIEW LOOKING SOUTH OF BUILDING 272 (STORAGE STRUCTURE A-2 IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  14. 43. EAST FRONT ELEVATION OF BUILDING 272 (STORAGE STRUCTURE A2) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    43. EAST FRONT ELEVATION OF BUILDING 272 (STORAGE STRUCTURE A-2) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  15. 21. DETAIL OF STRUCTURAL BAY ON NORTH ELEVATION OF BUILDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. DETAIL OF STRUCTURAL BAY ON NORTH ELEVATION OF BUILDING 216 (AMMUNITION MAINTENANCE SHOP) IN ASSEMBLY AREA. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  16. Assembly, alignment and test of the Transiting Exoplanet Survey Satellite (TESS) optical assemblies

    NASA Astrophysics Data System (ADS)

    Balonek, Gregory; Brown, Joshua J.; Andre, James E.; Chesbrough, Christian D.; Chrisp, Michael P.; Dalpiaz, Michael; Lennon, Joseph; Richards, B. C.; Clark, Kristin E.

    2017-08-01

    The Transiting Exoplanet Survey Satellite (TESS) will carry four visible waveband, seven-element, refractive F/1.4 lenses, each with a 34 degree diagonal field of view. This paper describes the methods used for the assembly, alignment and test of the four flight optical assemblies. Prior to commencing the build of the four flight optical assemblies, a Risk Reduction Unit (RRU) was successfully assembled and tested [1]. The lessons learned from the RRU were applied to the build of the flight assemblies. The main modifications to the flight assemblies include the inking of the third lens element stray light mitigation, tighter alignment tolerances, and diamond turning for critical mechanical surfaces. Each of the optical assemblies was tested interferometrically and measured with a low coherence distance measuring interferometer (DMI) to predict the optimal shim thickness between the lens assembly and detector before -75°C environmental testing. In addition to individual test data, environmental test results from prior assemblies allow for the exploration of marginal performance differences between each of the optical assemblies.

  17. 44. NORTHWEST CORNER OF BUILDING 272 (STORAGE STRUCTURE A2) IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    44. NORTHWEST CORNER OF BUILDING 272 (STORAGE STRUCTURE A-2) IN ASSEMBLY AREA SHOWING SHAPE OF EARTHEN BERM. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  18. Modern Offices: A User Survey. National Building Studies Research Paper 41.

    ERIC Educational Resources Information Center

    Langdon, F. J.

    A record and assessment of the important environmental features of office buildings erected between 1948 and 1961 in the business center of London, England, has been assembled. This survey gives an overall picture of the main trends in office building and architecture and examines their consequences in terms of user satisfactions and complaints.…

  19. 20. NORTHWEST CORNER OF BUILDING 216 (AMMUNITION MAINTENANCE SHOP) IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. NORTHWEST CORNER OF BUILDING 216 (AMMUNITION MAINTENANCE SHOP) IN ASSEMBLY AREA SHOWING SHAPE OF EARTHEN MOUND COVERING AND RETAINING WALL. - Loring Air Force Base, Weapons Storage Area, Northeastern corner of base at northern end of Maine Road, Limestone, Aroostook County, ME

  20. GENERAL VIEW OF THE MAIN FLOOR LEVEL, PLATFORM DSOUTH, HB3, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL VIEW OF THE MAIN FLOOR LEVEL, PLATFORM D-SOUTH, HB-3, FACING NORTHWEST - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  1. DETAIL VIEW OF VIDEO CAMERA, MAIN FLOOR LEVEL, PLATFORM ESOUTH, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW OF VIDEO CAMERA, MAIN FLOOR LEVEL, PLATFORM E-SOUTH, HB-3, FACING SOUTHWEST - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  2. Analysis on the hot spot and trend of the foreign assembly building research

    NASA Astrophysics Data System (ADS)

    Bi, Xiaoqing; Luo, Yanbing

    2017-03-01

    First of all, the paper analyzes the research on the front of the assembly building in the past 15 years. This article mainly adopts the method of CO word analysis, construct the co word matrix, correlation matrix, and then into a dissimilarity matrix, and on this basis, using factor analysis, cluster analysis and multi scale analysis method to study the structure of prefabricated construction field display. Finally, the results of the analysis are discussed, and summarized the current research focus of foreign prefabricated construction mainly concentrated in 7 aspects: embankment construction, wood construction, bridge construction, crane layout, PCM wall and glass system, based on neural network test, energy saving and recycling, and forecast the future trend of development study.

  3. Peptide self-assembly: thermodynamics and kinetics.

    PubMed

    Wang, Juan; Liu, Kai; Xing, Ruirui; Yan, Xuehai

    2016-10-21

    Self-assembling systems play a significant role in physiological functions and have therefore attracted tremendous attention due to their great potential for applications in energy, biomedicine and nanotechnology. Peptides, consisting of amino acids, are among the most popular building blocks and programmable molecular motifs. Nanostructures and materials assembled using peptides exhibit important potential for green-life new technology and biomedical applications mostly because of their bio-friendliness and reversibility. The formation of these ordered nanostructures pertains to the synergistic effect of various intermolecular non-covalent interactions, including hydrogen-bonding, π-π stacking, electrostatic, hydrophobic, and van der Waals interactions. Therefore, the self-assembly process is mainly driven by thermodynamics; however, kinetics is also a critical factor in structural modulation and function integration. In this review, we focus on the influence of thermodynamic and kinetic factors on structural assembly and regulation based on different types of peptide building blocks, including aromatic dipeptides, amphiphilic peptides, polypeptides, and amyloid-relevant peptides.

  4. Multifunctional Nanoparticles Self-Assembled from Small Organic Building Blocks for Biomedicine.

    PubMed

    Xing, Pengyao; Zhao, Yanli

    2016-09-01

    Supramolecular self-assembly shows significant potential to construct responsive materials. By tailoring the structural parameters of organic building blocks, nanosystems can be fabricated, whose performance in catalysis, energy storage and conversion, and biomedicine has been explored. Since small organic building blocks are structurally simple, easily modified, and reproducible, they are frequently employed in supramolecular self-assembly and materials science. The dynamic and adaptive nature of self-assembled nanoarchitectures affords an enhanced sensitivity to the changes in environmental conditions, favoring their applications in controllable drug release and bioimaging. Here, recent significant research advancements of small-organic-molecule self-assembled nanoarchitectures toward biomedical applications are highlighted. Functionalized assemblies, mainly including vesicles, nanoparticles, and micelles are categorized according to their topological morphologies and functions. These nanoarchitectures with different topologies possess distinguishing advantages in biological applications, well incarnating the structure-property relationship. By presenting some important discoveries, three domains of these nanoarchitectures in biomedical research are covered, including biosensors, bioimaging, and controlled release/therapy. The strategies regarding how to design and characterize organic assemblies to exhibit biomedical applications are also discussed. Up-to-date research developments in the field are provided and research challenges to be overcome in future studies are revealed. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Interior, building 1205, view to southeast showing roof truss system, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior, building 1205, view to southeast showing roof truss system, sliding main doors, and roll up door at center to allow clearance for aircraft tail assembly, 90 mm lens plus electronic flash fill lighting. - Travis Air Force Base, Readiness Maintenance Hangar, W Street, Air Defense Command Readiness Area, Fairfield, Solano County, CA

  6. Microfluidic assembly blocks.

    PubMed

    Rhee, Minsoung; Burns, Mark A

    2008-08-01

    An assembly approach for microdevice construction using prefabricated microfluidic components is presented. Although microfluidic systems are convenient platforms for biological assays, their use in the life sciences is still limited mainly due to the high-level fabrication expertise required for construction. This approach involves prefabrication of individual microfluidic assembly blocks (MABs) in PDMS that can be readily assembled to form microfluidic systems. Non-expert users can assemble the blocks on glass slides to build their devices in minutes without any fabrication steps. In this paper, we describe the construction and assembly of the devices using the MAB methodology, and demonstrate common microfluidic applications including laminar flow development, valve control, and cell culture.

  7. Insights into the microbial diversity and bioburden in a South American spacecraft assembly clean room.

    PubMed

    Schwendner, Petra; Moissl-Eichinger, Christine; Barczyk, Simon; Bohmeier, Maria; Pukall, Rüdiger; Rettberg, Petra

    2013-12-01

    In this study, samples from the spacecraft assembly clean room BAF (final assembly building), located at Centre Spatial Guyanais in Kourou, French Guiana, were characterized by qualitative and quantitative methods to determine the bioburden and biodiversity. The cultivation assays mainly focused on extremotolerant microorganisms that have special metabolic skills, such as the ability to grow without oxygen, fix nitrogen, grow autotrophically, or reduce sulfate. A broad range of media and growth conditions were used to simulate possible extraterrestrial environments and clean room buildings. In addition to these alternative cultivation assays, the ESA standard protocol for bioburden estimation was also applied. The phylogenetic analysis of the isolates (mainly facultative anaerobes) showed an extraordinarily broad cultivable biodiversity. Overall, 49 species were isolated and identified as members of the bacterial phyla Actinobacteria, Firmicutes, α-, β-, γ-Proteobacteria, and Bacteroidetes/Chlorobi. In addition to cultivation-based analyses, molecular techniques were also applied, including construction of a 16S rRNA gene clone library. The results indicate a wide-ranging microbial diversity (12 bacterial phyla, 34 families) that not only confirms the results of the cultivation efforts but also deepens our understanding of the noncultivable variety. Our investigations hint at a very broad, mainly uncultivated microbial diversity.

  8. Highly crystalline covalent organic frameworks from flexible building blocks.

    PubMed

    Xu, Liqian; Ding, San-Yuan; Liu, Junmin; Sun, Junliang; Wang, Wei; Zheng, Qi-Yu

    2016-03-28

    Two novel 2D covalent organic frameworks (TPT-COF-1 and TPT-COF-2) were synthesized from the flexible 2,4,6-triaryloxy-1,3,5-triazine building blocks on a gram scale, which show high crystallinity and large surface area. The controllable formation of highly ordered frameworks is mainly attributed to the self-assembly Piedfort unit of 2,4,6-triaryloxy-1,3,5-triazine.

  9. 58. Neg. No. F160a, Jan 11, 1933, INTERIOROFFICE BUILDING/ ASSEMBLY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    58. Neg. No. F-160a, Jan 11, 1933, INTERIOR-OFFICE BUILDING/ ASSEMBLY BUILDING, FIRST AID ROOM - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  10. A chronicle of galaxy mass assembly in the EAGLE simulation

    NASA Astrophysics Data System (ADS)

    Qu, Yan; Helly, John C.; Bower, Richard G.; Theuns, Tom; Crain, Robert A.; Frenk, Carlos S.; Furlong, Michelle; McAlpine, Stuart; Schaller, Matthieu; Schaye, Joop; White, Simon D. M.

    2017-01-01

    We analyse the mass assembly of central galaxies in the Evolution and Assembly of Galaxies and their Environments (EAGLE) hydrodynamical simulations. We build merger trees to connect galaxies to their progenitors at different redshifts and characterize their assembly histories by focusing on the time when half of the galaxy stellar mass was assembled into the main progenitor. We show that galaxies with stellar mass M* < 1010.5 M⊙ assemble most of their stellar mass through star formation in the main progenitor (`in situ' star formation). This can be understood as a consequence of the steep rise in star formation efficiency with halo mass for these galaxies. For more massive galaxies, however, an increasing fraction of their stellar mass is formed outside the main progenitor and subsequently accreted. Consequently, while for low-mass galaxies, the assembly time is close to the stellar formation time, the stars in high-mass galaxies typically formed long before half of the present-day stellar mass was assembled into a single object, giving rise to the observed antihierarchical downsizing trend. In a typical present-day M* ≥ 1011 M⊙ galaxy, around 20 per cent of the stellar mass has an external origin. This fraction decreases with increasing redshift. Bearing in mind that mergers only make an important contribution to the stellar mass growth of massive galaxies, we find that the dominant contribution comes from mergers with galaxies of mass greater than one-tenth of the main progenitor's mass. The galaxy merger fraction derived from our simulations agrees with recent observational estimates.

  11. Deconstructing Building Blocks: Preschoolers' Spatial Assembly Performance Relates to Early Mathematics Skills

    PubMed Central

    Verdine, Brian N.; Golinkoff, Roberta Michnick; Hirsh-Pasek, Kathryn; Newcombe, Nora S.; Filipowicz, Andrew T.; Chang, Alicia

    2013-01-01

    This study focuses on three main goals: First, 3-year-olds' spatial assembly skills are probed using interlocking block constructions (N = 102). A detailed scoring scheme provides insight into early spatial processing and offers information beyond a basic accuracy score. Second, the relation of spatial assembly to early mathematics skills was evaluated. Spatial skill independently predicted a significant amount of the variability in concurrent mathematics performance. Finally, the relationship between spatial assembly skill and socioeconomic status, gender, and parent-reported spatial language was examined. While children's performance did not differ by gender, lower-SES children were already lagging behind higher-SES children in block assembly. Furthermore, lower-SES parents reported using significantly fewer spatial words with their children. PMID:24112041

  12. KSC-2012-1852

    NASA Image and Video Library

    2012-02-17

    Industrial Area Construction: Located 5 miles south of Launch Complex 39, construction of the main buildings -- Operations and Checkout Building, Headquarters Building, and Central Instrumentation Facility – began in 1963. In 1992, the Space Station Processing Facility was designed and constructed for the pre-launch processing of International Space Station hardware that was flown on the space shuttle. Along with other facilities, the industrial area provides spacecraft assembly and checkout, crew training, computer and instrumentation equipment, hardware preflight testing and preparations, as well as administrative offices. Poster designed by Kennedy Space Center Graphics Department/Greg Lee. Credit: NASA

  13. 1. MISSILE TEST AND ASSEMBLY BUILDING, FRONT, LOOKING SOUTH. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. MISSILE TEST AND ASSEMBLY BUILDING, FRONT, LOOKING SOUTH. - NIKE Missile Base SL-40, Missile Test & Assembly Building, South end of launch area, northeast of Generator Building No. 3, Hecker, Monroe County, IL

  14. 97. JOB NO. 1347F, SHEET 5, 1927, ASSEMBLY BUILDING; FORD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    97. JOB NO. 1347-F, SHEET 5, 1927, ASSEMBLY BUILDING; FORD MOTOR COMPANY; ELEVATIONS AND DOOR DETAILS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  15. 105. JOB NO. 1347F, SHEET 15, 1927/1929, ASSEMBLY BUILDING; FORD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    105. JOB NO. 1347-F, SHEET 15, 1927/1929, ASSEMBLY BUILDING; FORD MOTOR COMPANY; MISCELLANEOUS DETAILS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  16. 98. JOB NO. 1347F, SHEET 7, 1927/1929, ASSEMBLY BUILDING; FORD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    98. JOB NO. 1347-F, SHEET 7, 1927/1929, ASSEMBLY BUILDING; FORD MOTOR COMPANY; EXTERIOR DETAILS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  17. 99. JOB NO. 1347F, SHEET 14, 1929, ASSEMBLY BUILDING; FORD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    99. JOB NO. 1347-F, SHEET 14, 1929, ASSEMBLY BUILDING; FORD MOTOR COMPANY; OFFICE SECTIONS AND DETAILS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  18. 102. JOB NO. 1347F, SHEET 3, 1927, ASSEMBLY BUILDING; FORD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    102. JOB NO. 1347-F, SHEET 3, 1927, ASSEMBLY BUILDING; FORD MOTOR COMPANY; FIRST FLOOR PLAN - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  19. 106. JOB NO. 1347F, SHEET 9, 1927, ASSEMBLY BUILDING; FORD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    106. JOB NO. 1347-F, SHEET 9, 1927, ASSEMBLY BUILDING; FORD MOTOR COMPANY; TOILET-SECTION AND DETAILS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  20. 110. JOB NO. 1347F, SHEET 11, 1927, ASSEMBLY BUILDING; FORD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    110. JOB NO. 1347-F, SHEET 11, 1927, ASSEMBLY BUILDING; FORD MOTOR COMPANY; WAREHOUSE SECTION AND DETAILS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  1. 111. JOB NO. 1347F, SHEET 12, 1927/1929, ASSEMBLY BUILDING; FORD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    111. JOB NO. 1347-F, SHEET 12, 1927/1929, ASSEMBLY BUILDING; FORD MOTOR COMPANY; WAREHOUSE DETAILS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  2. 4. MISSILE TEST AND ASSEMBLY BUILDING, LEFT SIDE, LOOKING NORTH. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. MISSILE TEST AND ASSEMBLY BUILDING, LEFT SIDE, LOOKING NORTH. - NIKE Missile Base SL-40, Missile Test & Assembly Building, South end of launch area, northeast of Generator Building No. 3, Hecker, Monroe County, IL

  3. 2. MISSILE TEST AND ASSEMBLY BUILDING, RIGHT SIDE, LOOKING WEST. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. MISSILE TEST AND ASSEMBLY BUILDING, RIGHT SIDE, LOOKING WEST. - NIKE Missile Base SL-40, Missile Test & Assembly Building, South end of launch area, northeast of Generator Building No. 3, Hecker, Monroe County, IL

  4. 3. MISSILE TEST AND ASSEMBLY BUILDING, REAR SIDE, LOOKING NORTH. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. MISSILE TEST AND ASSEMBLY BUILDING, REAR SIDE, LOOKING NORTH. - NIKE Missile Base SL-40, Missile Test & Assembly Building, South end of launch area, northeast of Generator Building No. 3, Hecker, Monroe County, IL

  5. 88. Neg. No. F124, Jul 9, 1931, INTERIORASSEMBLY BUILDING, SHOWING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    88. Neg. No. F-124, Jul 9, 1931, INTERIOR-ASSEMBLY BUILDING, SHOWING PARTIALLY ASSEMBLED CARS AND FENDER CONVEYORS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  6. 112. JOB NO. 1347F, SHEET 16, 1929/1930, ASSEMBLY BUILDING; FORD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    112. JOB NO. 1347-F, SHEET 16, 1929/1930, ASSEMBLY BUILDING; FORD MOTOR COMPANY; FREIGHT ELEVATOR DETAILS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  7. 100. JOB NO. 1347F, SHEET 13, 1927, ASSEMBLY BUILDING; FORD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    100. JOB NO. 1347-F, SHEET 13, 1927, ASSEMBLY BUILDING; FORD MOTOR COMPANY; DETAILS OF OFFICE AND SECTIONS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  8. 108. JOB NO. 1347F, SHEET 17, 1929, ASSEMBLY BUILDING; FORD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    108. JOB NO. 1347-F, SHEET 17, 1929, ASSEMBLY BUILDING; FORD MOTOR COMPANY; TUNNELs TRUSSES UNDER TANK, ETC. - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  9. 109. JOB NO. 1347F, SHEET 8S, 1929, ASSEMBLY BUILDING; FORD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    109. JOB NO. 1347-F, SHEET 8S, 1929, ASSEMBLY BUILDING; FORD MOTOR COMPANY; TRANSVERSE SECTION OF WAREHOUSE - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  10. 5. MISSILE TEST AND ASSEMBLY BUILDING, FRONT AND RIGHT SIDES, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. MISSILE TEST AND ASSEMBLY BUILDING, FRONT AND RIGHT SIDES, LOOKING SOUTHEAST. - NIKE Missile Base SL-40, Missile Test & Assembly Building, South end of launch area, northeast of Generator Building No. 3, Hecker, Monroe County, IL

  11. 6. MISSILE TEST AND ASSEMBLY BUILDING, REAR AND LEFT SIDES, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. MISSILE TEST AND ASSEMBLY BUILDING, REAR AND LEFT SIDES, LOOKING NORTHWEST. - NIKE Missile Base SL-40, Missile Test & Assembly Building, South end of launch area, northeast of Generator Building No. 3, Hecker, Monroe County, IL

  12. 96. JOB NO. 1347F, SHEET 6, 1927/1929, ASSEMBLY BUILDING; FORD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    96. JOB NO. 1347-F, SHEET 6, 1927/1929, ASSEMBLY BUILDING; FORD MOTOR COMPANY; NORTH, EAST, AND SOUTH ELEVATIONS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  13. 101. JOB NO. 1347F, SHEET 3M, 1927, ASSEMBLY BUILDING; FORD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    101. JOB NO. 1347-F, SHEET 3M, 1927, ASSEMBLY BUILDING; FORD MOTOR COMPANY; ONE-EIGHTH SCALE OF OFFICES - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  14. 104. JOB NO. 1347F, SHEET 5S 1927, ASSEMBLY BUILDING; FORD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    104. JOB NO. 1347-F, SHEET 5S 1927, ASSEMBLY BUILDING; FORD MOTOR COMPANY; LONGITUDINAL SECTION AND TRUSS DETAILS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  15. 103. JOB NO. 1347F, SHEET 4, 1927/1929, ASSEMBLY BUILDING; FORD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    103. JOB NO. 1347-F, SHEET 4, 1927/1929, ASSEMBLY BUILDING; FORD MOTOR COMPANY; ROOF PLAN CROSS SECTION AND DETAIL - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  16. Pulsed electric field assisted assembly of polyaniline

    NASA Astrophysics Data System (ADS)

    Kumar, Arun; Kazmer, David O.; Barry, Carol M. F.; Mead, Joey L.

    2012-08-01

    Assembling conducting polyaniline (PANi) on pre-patterned nano-structures by a high rate, commercially viable route offers an opportunity for manufacturing devices with nanoscale features. In this work we report for the first time the use of pulsed electric field to assist electrophoresis for the assembly of conducting polyaniline on gold nanowire interdigitated templates. This technique offers dynamic control over heat build-up, which has been a main drawback in the DC electrophoresis and AC dielectrophoresis as well as the main cause of nanowire template damage. The use of this technique allowed higher voltages to be applied, resulting in shorter assembly times (e.g., 17.4 s, assembly resolution of 100 nm). Moreover, the area coverage increases with the increase in number of pulses. A similar trend was observed with the deposition height and the increase in deposition height followed a linear trend with a correlation coefficient of 0.95. When the experimental mass deposited was compared with Hamaker’s theoretical model, the two were found to be very close. The pre-patterned templates with PANi deposition were subsequently used to transfer the nanoscale assembled PANi from the rigid templates to thermoplastic polyurethane using the thermoforming process.

  17. KSC-2010-4643

    NASA Image and Video Library

    2010-09-10

    CAPE CANAVERAL, Fla. -- In the Launch Complex-39 Turn Basin area, across from the Vehicle Assembly Building at NASA's Kennedy Space Center in Florida, the section of a 24-inch cast iron water main pipe that failed is hauled away by a transport truck. Kennedy was closed to non-essential personnel the morning of Sept. 8 while crews assessed the water main break and restored water to the center. Photo credit: NASA/Jack Pfaller

  18. 91. Neg. No. F174A, Apr 24, 1936, INTERIORASSEMBLY BUILDING, FINISHED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    91. Neg. No. F-174A, Apr 24, 1936, INTERIOR-ASSEMBLY BUILDING, FINISHED CARS AT THE END OF THE ASSEMBLY LINE - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  19. Trade Related Reading Packets for Disabled Readers.

    ERIC Educational Resources Information Center

    Davis, Beverly; Woodruff, Nancy S.

    Six trade-related reading packets for disabled readers are provided for these trades: assemblers, baking, building maintenance, data entry, interior landscaping, and warehousing. Each packet stresses from 9 to 14 skills. Those skills common to most packets include context clues, fact or opinion, details, following directions, main idea,…

  20. 2. MISSILE ASSEMBLY BUILDING, RIGHT SIDE, LOOKING NORTH. NIKE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. MISSILE ASSEMBLY BUILDING, RIGHT SIDE, LOOKING NORTH. - NIKE Missile Base C-84, Missile Test & Assembly Building, North of Launch Area Entrance Drive & east of Mess Hall, Barrington, Cook County, IL

  1. Multicriteria Analysis of Assembling Buildings from Steel Frame Structures

    NASA Astrophysics Data System (ADS)

    Miniotaite, Ruta

    2017-10-01

    Steel frame structures are often used in the construction of public and industrial buildings. They are used for: all types of slope roofs; walls of newly-built public and industrial buildings; load bearing structures; roofs of renovated buildings. The process of assembling buildings from steel frame structures should be analysed as an integrated process influenced by such factors as construction materials and machinery used, the qualification level of construction workers, complexity of work, available finance. It is necessary to find a rational technological design solution for assembling buildings from steel frame structures by conducting a multiple criteria analysis. The analysis provides a possibility to evaluate the engineering considerations and find unequivocal solutions. The rational alternative of a complex process of assembling buildings from steel frame structures was found through multiple criteria analysis and multiple criteria evaluation. In multiple criteria evaluation of technological solutions for assembling buildings from steel frame structures by pairwise comparison method the criteria by significance are distributed as follows: durability is the most important criterion in the evaluation of alternatives; the price (EUR/unit of measurement) of a part of assembly process; construction workers’ qualification level (category); mechanization level of a part of assembling process (%), and complexity of assembling work (in points) are less important criteria.

  2. 81. Neg. No. F63, Apr 13, 1930, INTERIORASSEMBLY BUILDING, HOOD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    81. Neg. No. F-63, Apr 13, 1930, INTERIOR-ASSEMBLY BUILDING, HOOD DEPARTMENT - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  3. 83. Neg. No. F53, Apr 13, 1930, INTERIORASSEMBLY BUILDING, BACK ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    83. Neg. No. F-53, Apr 13, 1930, INTERIOR-ASSEMBLY BUILDING, BACK TRIM LINE - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  4. 85. Neg. No. F51, Apr 13, 1930, INTERIORASSEMBLY BUILDING, BODY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    85. Neg. No. F-51, Apr 13, 1930, INTERIOR-ASSEMBLY BUILDING, BODY AND CUSHION LINE - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  5. 79. Neg. No. F61A, Apr 13, 1930, INTERIORASSEMBLY BUILDING, BODY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    79. Neg. No. F-61A, Apr 13, 1930, INTERIOR-ASSEMBLY BUILDING, BODY CONSTRUCTION - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  6. 89. Neg. No. F126, Jul 21, 1931, INTERIORASSEMBLY BUILDING, SHOWING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    89. Neg. No. F-126, Jul 21, 1931, INTERIOR-ASSEMBLY BUILDING, SHOWING HEADLIGHT TESTING BOOTH - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  7. 92. Neg. No. F142, Mar 29, 1932, INTERIORASSEMBLY BUILDING, STAGE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    92. Neg. No. F-142, Mar 29, 1932, INTERIOR-ASSEMBLY BUILDING, STAGE AND EXHIBITION ROOM - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  8. 86. Neg. No. F64, Apr 13, 1930, INTERIORASSEMBLY BUILDING, BODY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    86. Neg. No. F-64, Apr 13, 1930, INTERIOR-ASSEMBLY BUILDING, BODY STORAGE CONVEYOR - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  9. 65. Neg. No. F99, Dec 27, 1931, INTERIORPRESSED STEEL BUILDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    65. Neg. No. F-99, Dec 27, 1931, INTERIOR-PRESSED STEEL BUILDING FACING SOUTH TOWARD WAREHOUSE AND ASSEMBLY BUILDING 1ST FLOOR, EAST SIDE FACING SOUTH, SHOWING PRESSED STEEL MACHINERY AND RAILROAD CARS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  10. 94. Neg. No. F130, Sep 24, 1931, EXTERIOROFFICE BUILDING AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    94. Neg. No. F-130, Sep 24, 1931, EXTERIOR-OFFICE BUILDING AND ASSEMBLY BUILDING, WEST SIDE, SHOWING TRUCKS AND TRAILORS LOADED WITH NEW TRUCKS DISPLAYING SIGNS 'MORE FORDS FOR HOOVER DAM' - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  11. 76. Neg. No. F58, Apr 13, 1930, INTERIORASSEMBLY BUILDING, BURNOFF, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    76. Neg. No. F-58, Apr 13, 1930, INTERIOR-ASSEMBLY BUILDING, BURNOFF, LOAD END OF ENAMEL OVEN - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  12. 77. Neg. No. F65A, Apr 13, 1930, INTERIORASSEMBLY BUILDING, UNLOADING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    77. Neg. No. F-65A, Apr 13, 1930, INTERIOR-ASSEMBLY BUILDING, UNLOADING THE ENAMEL OVEN - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  13. 90. Neg. No. F59A, Apr 13, 1930, INTERIORASSEMBLY BUILDING, CHASSIS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    90. Neg. No. F-59A, Apr 13, 1930, INTERIOR-ASSEMBLY BUILDING, CHASSIS LINE, LOOKING SOUTH - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  14. 87. Neg. No. F74A, Jun 14, 1930, INTERIORASSEMBLY BUILDING, BODY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    87. Neg. No. F-74A, Jun 14, 1930, INTERIOR-ASSEMBLY BUILDING, BODY STORAGE CONVEYORS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  15. 84. Neg. No. F62, Apr 13, 1930, INTERIORASSEMBLY BUILDING, FRAME ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    84. Neg. No. F-62, Apr 13, 1930, INTERIOR-ASSEMBLY BUILDING, FRAME AND MOTOR STORAGE CONVEYOR - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  16. 82. Neg. No. F66A, Apr 13, 1930, INTERIORASSEMBLY BUILDING, TRIM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    82. Neg. No. F-66A, Apr 13, 1930, INTERIOR-ASSEMBLY BUILDING, TRIM LINE AND GLASS DEPARTMENTS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  17. 78. Neg. No. F143A, Apr 1, 1932, INTERIORASSEMBLY BUILDING, CONVEYOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    78. Neg. No. F-143A, Apr 1, 1932, INTERIOR-ASSEMBLY BUILDING, CONVEYOR LINE WITH CAR CHASSIS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  18. Photovoltaic building sheathing element with anti-slide features

    DOEpatents

    Keenihan, James R.; Langmaid, Joseph A.; Lopez, Leonardo C.

    2015-09-08

    The present invention is premised` upon an assembly that includes at least a photovoltaic building sheathing element capable of being affixed on a building structure, the photovoltaic building sheathing element. The element including a photovoltaic cell assembly, a body portion attached to one or more portions of the photovoltaic cell assembly; and at feast a first and a second connector assembly capable of directly or indirectly electrically connecting the photovoltaic cell assembly to one or more adjoining devices; wherein the body portion includes one or more geometric features adapted to engage a vertically adjoining device before installation.

  19. BORED AND ASSEMBLED GATE VALVES RECEIVING PROTECTIVE COATING IN THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    BORED AND ASSEMBLED GATE VALVES RECEIVING PROTECTIVE COATING IN THE VALVE PAINT BOOTH OF THE VALVE ASSEMBLY BUILDING. - Stockham Pipe & Fittings Company, Valve Assembly Building, 4000 Tenth Avenue North, Birmingham, Jefferson County, AL

  20. Robotically Assembled Aerospace Structures: Digital Material Assembly using a Gantry-Type Assembler

    NASA Technical Reports Server (NTRS)

    Trinh, Greenfield; Copplestone, Grace; O'Connor, Molly; Hu, Steven; Nowak, Sebastian; Cheung, Kenneth; Jenett, Benjamin; Cellucci, Daniel

    2017-01-01

    This paper evaluates the development of automated assembly techniques for discrete lattice structures using a multi-axis gantry type CNC machine. These lattices are made of discrete components called digital materials. We present the development of a specialized end effector that works in conjunction with the CNC machine to assemble these lattices. With this configuration we are able to place voxels at a rate of 1.5 per minute. The scalability of digital material structures due to the incremental modular assembly is one of its key traits and an important metric of interest. We investigate the build times of a 5x5 beam structure on the scale of 1 meter (325 parts), 10 meters (3,250 parts), and 30 meters (9,750 parts). Utilizing the current configuration with a single end effector, performing serial assembly with a globally fixed feed station at the edge of the build volume, the build time increases according to a scaling law of n4, where n is the build scale. Build times can be reduced significantly by integrating feed systems into the gantry itself, resulting in a scaling law of n3. A completely serial assembly process will encounter time limitations as build scale increases. Automated assembly for digital materials can assemble high performance structures from discrete parts, and techniques such as built in feed systems, parallelization, and optimization of the fastening process will yield much higher throughput.

  1. Robotically Assembled Aerospace Structures: Digital Material Assembly using a Gantry-Type Assembler

    NASA Technical Reports Server (NTRS)

    Trinh, Greenfield; Copplestone, Grace; O'Connor, Molly; Hu, Steven; Nowak, Sebastian; Cheung, Kenneth; Jenett, Benjamin; Cellucci, Daniel

    2017-01-01

    This paper evaluates the development of automated assembly techniques for discrete lattice structures using a multi-axis gantry type CNC machine. These lattices are made of discrete components called "digital materials." We present the development of a specialized end effector that works in conjunction with the CNC machine to assemble these lattices. With this configuration we are able to place voxels at a rate of 1.5 per minute. The scalability of digital material structures due to the incremental modular assembly is one of its key traits and an important metric of interest. We investigate the build times of a 5x5 beam structure on the scale of 1 meter (325 parts), 10 meters (3,250 parts), and 30 meters (9,750 parts). Utilizing the current configuration with a single end effector, performing serial assembly with a globally fixed feed station at the edge of the build volume, the build time increases according to a scaling law of n4, where n is the build scale. Build times can be reduced significantly by integrating feed systems into the gantry itself, resulting in a scaling law of n3. A completely serial assembly process will encounter time limitations as build scale increases. Automated assembly for digital materials can assemble high performance structures from discrete parts, and techniques such as built in feed systems, parallelization, and optimization of the fastening process will yield much higher throughput.

  2. 56. V2 ASSEMBLY BUILDING (BUILDING 1538): VIEW FROM NORTHEAST, WITH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    56. V-2 ASSEMBLY BUILDING (BUILDING 1538): VIEW FROM NORTHEAST, WITH MILL BUILDING IN BACKGROUND AT FAR RIGHT - White Sands Missile Range, V-2 Rocket Facilities, Near Headquarters Area, White Sands, Dona Ana County, NM

  3. 93. Neg. No. F78K, Aug 11, 1930, EXTERIORASSEMBLY BUILDING, NORTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    93. Neg. No. F-78K, Aug 11, 1930, EXTERIOR-ASSEMBLY BUILDING, NORTH SIDE, WITH TAYLOR-TRUCK-A-WAY TRUCKS AND TRAILORS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  4. Control of peptide nanotube diameter by chemical modifications of an aromatic residue involved in a single close contact

    PubMed Central

    Tarabout, Christophe; Roux, Stéphane; Gobeaux, Frédéric; Fay, Nicolas; Pouget, Emilie; Meriadec, Cristelle; Ligeti, Melinda; Thomas, Daniel; IJsselstijn, Maarten; Besselievre, François; Buisson, David-Alexandre; Verbavatz, Jean-Marc; Petitjean, Michel; Valéry, Céline; Perrin, Lionel; Rousseau, Bernard; Artzner, Franck; Paternostre, Maité; Cintrat, Jean-Christophe

    2011-01-01

    Supramolecular self-assembly is an attractive pathway for bottom-up synthesis of novel nanomaterials. In particular, this approach allows the spontaneous formation of structures of well-defined shapes and monodisperse characteristic sizes. Because nanotechnology mainly relies on size-dependent physical phenomena, the control of monodispersity is required, but the possibility of tuning the size is also essential. For self-assembling systems, shape, size, and monodispersity are mainly settled by the chemical structure of the building block. Attempts to change the size notably by chemical modification usually end up with the loss of self-assembly. Here, we generated a library of 17 peptides forming nanotubes of monodisperse diameter ranging from 10 to 36 nm. A structural model taking into account close contacts explains how a modification of a few Å of a single aromatic residue induces a fourfold increase in nanotube diameter. The application of such a strategy is demonstrated by the formation of silica nanotubes of various diameters. PMID:21518895

  5. 95. JOB NO. 1347F, SHEET 1, 1927/1931, PLOT PLAN, ASSEMBLY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    95. JOB NO. 1347-F, SHEET 1, 1927/1931, PLOT PLAN, ASSEMBLY BUILDING FOR FORD MOTOR COMPANY, LONG BEACH, CALIFORNIA - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  6. Solvent mediated hybrid 2D materials: black phosphorus - graphene heterostructured building blocks assembled for sodium ion batteries.

    PubMed

    Li, Mengya; Muralidharan, Nitin; Moyer, Kathleen; Pint, Cary L

    2018-06-07

    Here we demonstrate the broad capability to exploit interactions at different length scales in 2D materials to prepare macroscopic functional materials containing hybrid black phosphorus/graphene (BP/G) heterostructured building blocks. First, heterostructured 2D building blocks are self-assembled during co-exfoliation in the solution phase based on electrostatic attraction of different 2D materials. Second, electrophoretic deposition is used as a tool to assemble these building blocks into macroscopic films containing these self-assembled 2D heterostructures. Characterization of deposits formed using this technique elucidates the presence of stacked and sandwiched 2D heterostructures, and zeta potential measurements confirm the mechanistic interactions driving this assembly. Building on the exceptional sodium alloying capacity of BP, these materials were demonstrated as superior binder-free and additive-free anodes for sodium batteries with specific discharge capacity of 2365 mA h gP-1 and long stable cycling duration. This study demonstrates how controllable co-processing of 2D materials can enable material control for stacking and building block assembly relevant to broad future applications of 2D materials.

  7. Light-emitting self-assembled peptide nucleic acids exhibit both stacking interactions and Watson-Crick base pairing.

    PubMed

    Berger, Or; Adler-Abramovich, Lihi; Levy-Sakin, Michal; Grunwald, Assaf; Liebes-Peer, Yael; Bachar, Mor; Buzhansky, Ludmila; Mossou, Estelle; Forsyth, V Trevor; Schwartz, Tal; Ebenstein, Yuval; Frolow, Felix; Shimon, Linda J W; Patolsky, Fernando; Gazit, Ehud

    2015-04-01

    The two main branches of bionanotechnology involve the self-assembly of either peptides or DNA. Peptide scaffolds offer chemical versatility, architectural flexibility and structural complexity, but they lack the precise base pairing and molecular recognition available with nucleic acid assemblies. Here, inspired by the ability of aromatic dipeptides to form ordered nanostructures with unique physical properties, we explore the assembly of peptide nucleic acids (PNAs), which are short DNA mimics that have an amide backbone. All 16 combinations of the very short di-PNA building blocks were synthesized and assayed for their ability to self-associate. Only three guanine-containing di-PNAs-CG, GC and GG-could form ordered assemblies, as observed by electron microscopy, and these di-PNAs efficiently assembled into discrete architectures within a few minutes. The X-ray crystal structure of the GC di-PNA showed the occurrence of both stacking interactions and Watson-Crick base pairing. The assemblies were also found to exhibit optical properties including voltage-dependent electroluminescence and wide-range excitation-dependent fluorescence in the visible region.

  8. Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA, John F. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA, John F. Kennedy Space Center, Florida. Drawing 79K05424, Seelye Stevenson Value & Knecht, March, 1975. SITE WORK, GENERAL AREA PLAN. Sheet 8 of 207 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  9. Photocopy of drawing. VEHICLE ASSEMBLY BUILDING. NASA John F. Kennedy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VEHICLE ASSEMBLY BUILDING. NASA John F. Kennedy Space Center, Florida. File Number 79K06740, NASA, November 1975. SPACE & WEIGHT ALLOCATION, ORBITER PATH IN TRANSFER AISLE. Sheet 6 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  10. Savannah River Plant engineering and design history. Volume 4: 300/700 Areas & general services and facilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1957-01-01

    The primary function of the 300 Area is the production and preparation of the fuel and target elements required for the 100 Area production reactors. Uranium slugs and lithium-aluminium alloy control and blanket rods are prepared in separate structures. Other facilities include a test pile, a physics assembly laboratory, an office and change house, an electrical substation, and various service facilities such as rail lines, roads, sewers, steam and water distribution lines, etc. The 700 Area contains housing and facilities for plant management, general plant services, and certain technical activities. The technical buildings include the Main Technical Laboratory, the Wastemore » Concentration Building, the Health Physics Headquarters, and the Health Physics Calibration building. Sections of this report describe the following: development of the 300-M Area; selection and description of process; design of main facilities of the 300 Area; development of the 700-A Area; design of the main facilities of the 700 Area; and general services and facilities, including transportation, plant protection, waste disposal and drainage, site work, pilot plants, storage, and furniture and fixtures.« less

  11. Some Assembly Required: Building a Better Accountability System for California. Education Sector Reports

    ERIC Educational Resources Information Center

    Carey, Kevin

    2012-01-01

    For years California has been a leader in public education. In 1999, the state implemented some of the strongest content standards in the country through its main accountability metric, the Academic Performance Index (API). The state has also signed onto the Common Core State Standards, taking important steps to ensure its students are college-…

  12. Understanding of Protein Synthesis in a Living Cell

    ERIC Educational Resources Information Center

    Mustapha, Y.; Muhammad, S.

    2006-01-01

    The assembly of proteins takes place in the cytoplasm of a cell. There are three main steps. In initiation, far left, all the necessary parts of the process are brought together by a small molecule called a ribosome. During elongation, amino acids, the building blocks of proteins, are joined to one another in a long chain. The sequence in which…

  13. Self-Assembly: How Nature Builds

    ERIC Educational Resources Information Center

    Jones, M. Gail; Falvo, Michael R.; Broadwell, Bethany; Dotger, Sharon

    2006-01-01

    Self-assembly or spontaneous assembly is a process in which materials build themselves without assistance. This process plays a central role in the construction of biological structures and materials such as cells, viruses, and bone, and also in abiotic processes like phase transitions and crystal formation. The principles of self-assembly help…

  14. ARCHITECTURAL, 777M, PHYSICS ASSEMBLY LABORATORY BUILDING, EQUIPMENT ARRANGEMENT – SECTIONS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ARCHITECTURAL, 777-M, PHYSICS ASSEMBLY LABORATORY BUILDING, EQUIPMENT ARRANGEMENT – SECTIONS “B” AND “C” (W157132) - Physics Assembly Laboratory, Area A/M, Savannah River Site, Aiken, Aiken County, SC

  15. 13. VIEW NORTHEAST, BUILDING 12 INTERIOR, WIND TUNNEL FAN ASSEMBLY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. VIEW NORTHEAST, BUILDING 12 INTERIOR, WIND TUNNEL FAN ASSEMBLY - Naval Surface Warfare Center, Transonic Wind Tunnel Building, Bounded by Clara Barton Parkway & McArthur Boulevard, Silver Spring, Montgomery County, MD

  16. Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. Kennedy Space Center, Florida. File Number 79K05424, Seelye Stevenson Value & Knecht, March 1975. ALL PLATFORMS-ARCHITECTURAL, GENERAL ARRANGEMENT, EAST-WEST ELEVATIONS. Sheet 12 of 207 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  17. Vehicle Assembly Building (VAB)

    NASA Image and Video Library

    2017-09-27

    NASA's Vehicle Assembly Building at Kennedy Space Center in Florida was used to assemble and house American-crewed launch vehicles from 1968 to 2011. AT 3,684,883 cubic meters, it is one of the largest buildings in the world by volume. Inside the facility, High Bay 3 is being upgraded and modified to support processing of the agency's Space Launch System rocket and Orion spacecraft.

  18. 16. Exterior of assembly building (mold loft #2) used for ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. Exterior of assembly building (mold loft #2) used for runabout production, constructed CA. 1932. Most of the production run boats were assembled here. - Barbour Boat Works, Tryon Palace Drive, New Bern, Craven County, NC

  19. SynTrack: DNA Assembly Workflow Management (SynTrack) v2.0.1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    MENG, XIANWEI; SIMIRENKO, LISA

    2016-12-01

    SynTrack is a dynamic, workflow-driven data management system that tracks the DNA build process: Management of the hierarchical relationships of the DNA fragments; Monitoring of process tasks for the assembly of multiple DNA fragments into final constructs; Creations of vendor order forms with selectable building blocks. Organizing plate layouts barcodes for vendor/pcr/fusion/chewback/bioassay/glycerol/master plate maps (default/condensed); Creating or updating Pre-Assembly/Assembly process workflows with selected building blocks; Generating Echo pooling instructions based on plate maps; Tracking of building block orders, received and final assembled for delivering; Bulk updating of colony or PCR amplification information, fusion PCR and chewback results; Updating with QA/QCmore » outcome with .csv & .xlsx template files; Re-work assembly workflow enabled before and after sequencing validation; and Tracking of plate/well data changes and status updates and reporting of master plate status with QC outcomes.« less

  20. 19. Launch Area, general view of Missile Assembly Building and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. Launch Area, general view of Missile Assembly Building and Generator Building VIEW SOUTHWEST - NIKE Missile Battery PR-79, Launch Area, East Windsor Road south of State Route 101, Foster, Providence County, RI

  1. Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. Kennedy Space Center, Florida. File Number 79K05424, Seelye Stevenson Value & Knecht, March 1975. HIGH BAY 3, EXTENSIBLE WORK PLATFORM ‘E’, ROOF PLAN, ARCHITECTURAL. Sheet 22 of 207 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  2. Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. Kennedy Space Center, Florida. File Number 79K05424, Seelye Stevenson Value & Knecht, March 1975. HIGH BAY 3, EXTENSIBLE WORK PLATFORM ‘D’, 2ND FLOOR PLAN, ARCHITECTURAL. Sheet 38 of 207 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  3. Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. Kennedy Space Center, Florida. File Number 79K05424, Seelye Stevenson Value & Knecht, March 1975. HIGH BAY 3, EXTENSIBLE WORK PLATFORM ‘D’, ROOF PLAN, ARCHITECTURAL. Sheet 36 of 207 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  4. Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. Kennedy Space Center, Florida. File Number 79K05424, Seelye Stevenson Value & Knecht, March 1975. HIGH BAY 3, EXTENSIBLE WORK PLATFORM ‘D’, 3RD FLOOR PLAN, ARCHITECTURAL. Sheet 37 of 207 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  5. Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. Kennedy Space Center, Florida. File Number 79K05424, Seelye Stevenson Value & Knecht, March 1975. HIGH BAY 3, EXTENSIBLE WORK PLATFORM ‘C’, 2ND FLOOR PLAN, ARCHITECTURAL. Sheet 15 of 207 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  6. Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. Kennedy Space Center, Florida. File Number 79K05424, Seelye Stevenson Value & Knecht, March 1975. HIGH BAY 3, EXTENSIBLE WORK PLATFORM ‘C’, ROOF PLAN, ARCHITECTURAL. Sheet 14 of 207 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  7. Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. Kennedy Space Center, Florida. File Number 79K05424, Seelye Stevenson Value & Knecht, March 1975. HIGH BAY 3, EXTENSIBLE WORK PLATFORM ‘B’, ROOF PLAN, ARCHITECTURAL. Sheet 28 of 207 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  8. Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS. NASA John F. Kennedy Space Center, Florida. File Number 79K05424, Seelye Stevenson Value & Knecht, March 1975. HIGH BAY 3, EXTENSIBLE WORK PLATFORM ‘B’, 2ND FLOOR PLAN, ARCHITECTURAL. Sheet 29 of 207 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  9. Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS, HIGH BAY AREA. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS, HIGH BAY AREA. NASA John F. Kennedy Space Center, Florida. File Number 79K05424, Seelye Stevenson Value & Knecht, March 1975. TRANSFER AISLE NORTH DOOR,ARCHITECTURAL NORTH ELEVATION AND MISC. DETAILS. Sheet 78 of 207 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  10. ARCHITECTURAL, 777M, PHYSICS ASSEMBLY LABORATORY BUILDING, PLAN OF +13’1” AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ARCHITECTURAL, 777-M, PHYSICS ASSEMBLY LABORATORY BUILDING, PLAN OF +13’-1” AND +27’-0” FLOOR LEVELS (W157114) - Physics Assembly Laboratory, Area A/M, Savannah River Site, Aiken, Aiken County, SC

  11. DNA-programmable nanoparticle crystallization.

    PubMed

    Park, Sung Yong; Lytton-Jean, Abigail K R; Lee, Byeongdu; Weigand, Steven; Schatz, George C; Mirkin, Chad A

    2008-01-31

    It was first shown more than ten years ago that DNA oligonucleotides can be attached to gold nanoparticles rationally to direct the formation of larger assemblies. Since then, oligonucleotide-functionalized nanoparticles have been developed into powerful diagnostic tools for nucleic acids and proteins, and into intracellular probes and gene regulators. In contrast, the conceptually simple yet powerful idea that functionalized nanoparticles might serve as basic building blocks that can be rationally assembled through programmable base-pairing interactions into highly ordered macroscopic materials remains poorly developed. So far, the approach has mainly resulted in polymerization, with modest control over the placement of, the periodicity in, and the distance between particles within the assembled material. That is, most of the materials obtained thus far are best classified as amorphous polymers, although a few examples of colloidal crystal formation exist. Here, we demonstrate that DNA can be used to control the crystallization of nanoparticle-oligonucleotide conjugates to the extent that different DNA sequences guide the assembly of the same type of inorganic nanoparticle into different crystalline states. We show that the choice of DNA sequences attached to the nanoparticle building blocks, the DNA linking molecules and the absence or presence of a non-bonding single-base flexor can be adjusted so that gold nanoparticles assemble into micrometre-sized face-centred-cubic or body-centred-cubic crystal structures. Our findings thus clearly demonstrate that synthetically programmable colloidal crystallization is possible, and that a single-component system can be directed to form different structures.

  12. Installation of ventilated facades without scaffolding in high-rise buildings

    NASA Astrophysics Data System (ADS)

    Gnedina, Lyubov; Muchkina, Arina; Labutin, Alexander

    2018-03-01

    This article consider the use of polystyrene concrete blocks during assembling enclosing structure of ventilated facades in high-rise monolithic housing construction. Comparing with traditional technology devices hinged ventilated facade the main advantage of the proposed design is an exception of using scaffold, that leads to a cheapening of the enclosing structure. Proposed solutions are confirmed by patents of the Russian Federation.

  13. Oblique view at ground level looking at the aft and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Oblique view at ground level looking at the aft and port side of the Orbiter Discovery in the Vehicle Assembly Building at NASA's Kennedy Space Center. Note that the Orbiter Maneuvering System/Reaction Control System pods and the Shuttle Main Engines are removed in this image. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  14. 7. PHOTOCOPY, PLANS, ELEVATIONS, AND SECTION DRAWING FOR MISSILE TEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. PHOTOCOPY, PLANS, ELEVATIONS, AND SECTION DRAWING FOR MISSILE TEST AND ASSEMBLY BUILDING. - NIKE Missile Base SL-40, Missile Test & Assembly Building, South end of launch area, northeast of Generator Building No. 3, Hecker, Monroe County, IL

  15. 74. Neg. No. F116A, May 22, 1931, INTERIORPRESSED STEEL BUILDING, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    74. Neg. No. F-116A, May 22, 1931, INTERIOR-PRESSED STEEL BUILDING, SHOWING FENDER CRATE - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  16. Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS, HIGH BAY AREA. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. VEHICLE ASSEMBLY BUILDING MODIFICATIONS, HIGH BAY AREA. NASA John F. Kennedy Space Center, Florida. File Number 79K05424, Seelye Stevenson Value & Knecht, March 1975. TRANSFER AISLE NORTH DOOR, ARCHITECTURAL AND STRUCTURAL ELEVATIONS, SECTIONS AND DETAILS. Sheet 79 of 207 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  17. 41. ARAIII Prototype assembly and evaluation building ARA630. West end ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    41. ARA-III Prototype assembly and evaluation building ARA-630. West end and south side of building. Camera facing northeast. Ineel photo no. 3-22. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

  18. SOUTHERN END OF ASSEMBLY PLANT, LOOKING N ON SECOND FLOOR, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    SOUTHERN END OF ASSEMBLY PLANT, LOOKING N ON SECOND FLOOR, WHICH DID NOT EXIST ON DURING SHIP BUILDING DAYS. NOTE VEHICLE ELEVATOR. ABOVE AND TO THE LEFT IS SHIP BUILDING BALCONY. - B Building, 3001 Miller Road, Dearborn, MI

  19. 56. Neg. No. F161, Mar 18, 1933, INTERIOROFFICE BUILDING, LOBBY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    56. Neg. No. F-161, Mar 18, 1933, INTERIOR-OFFICE BUILDING, LOBBY AND STAIRWELL, SHOWING DAMAGE AFTER AN EARTHQUAKE - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  20. Rapid and annealing-free self-assembly of DNA building blocks for 3D hydrogel chaperoned by cationic comb-type copolymers.

    PubMed

    Zhang, Zheng; Wu, Yuyang; Yu, Feng; Niu, Chaoqun; Du, Zhi; Chen, Yong; Du, Jie

    2017-10-01

    The construction and self-assembly of DNA building blocks are the foundation of bottom-up development of three-dimensional DNA nanostructures or hydrogels. However, most self-assembly from DNA components is impeded by the mishybridized intermediates or the thermodynamic instability. To enable rapid production of complicated DNA objects with high yields no need for annealing process, herein different DNA building blocks (Y-shaped, L- and L'-shaped units) were assembled in presence of a cationic comb-type copolymer, poly (L-lysine)-graft-dextran (PLL-g-Dex), under physiological conditions. The results demonstrated that PLL-g-Dex not only significantly promoted the self-assembly of DNA blocks with high efficiency, but also stabilized the assembled multi-level structures especially for promoting the complicated 3D DNA hydrogel formation. This study develops a novel strategy for rapid and high-yield production of DNA hydrogel even derived from instable building blocks at relatively low DNA concentrations, which would endow DNA nanotechnology for more practical applications.

  1. Research on the Development Prospect of Assembled Passive Building Based on Green Development Concept

    NASA Astrophysics Data System (ADS)

    Lixin, Zhang; Ju, Ma; Baohui, He

    2018-02-01

    In recent years, the vigorous development of the construction industry has brought about serious problems of environmental pollution and resource consumption. In order to reduce the negative impact that the construction industry has on the natural environment,this paper, from the perspective of environmental protection, studies the pollution and high consumption problems existing in the production and use of traditional construction industry, compares and analyzes the green and energy-saving advantages in the construction and using phase of assembled passive building, and at the same time, combined with our country is vigorously promoting the assembled passive building and the green development, concluded that the assembled passive building is the new development direction of China’s construction industry.

  2. LPT. Shield test facility assembly and test building (TAN646), south ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    LPT. Shield test facility assembly and test building (TAN-646), south facade. Camera facing north. High-bay section is pool room. Single-story section at right is control building (TAN-645). Small metal building is post-1970 addition. INEEL negative no. HD-40-7-3 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

  3. Two innovative solutions based on fibre concrete blocks designed for building substructure

    NASA Astrophysics Data System (ADS)

    Pazderka, J.; Hájek, P.

    2017-09-01

    Using of fibers in a high-strength concrete allows reduction of the dimensions of small precast concrete elements, which opens up new ways of solution for traditional construction details in buildings. The paper presents two innovative technical solutions for building substructure: The special shaped plinth block from fibre concrete and the fibre concrete elements for new technical solution of ventilated floor. The main advantages of plinth block from fibre concrete blocks (compared with standard plinth solutions) is: easier and faster assembly, higher durability and thanks to the air cavity between the vertical part of the block, the building substructure reduced moisture level of structures under the waterproofing layer and a comprehensive solution to the final surface of building plinth as well as the surface of adjacent terrain. The ventilated floor based on fibre concrete precast blocks is an attractive structural alternative for tackling the problem of increased moisture in masonry in older buildings, lacking a functional waterproof layer in the substructure.

  4. 10 CFR 434.402 - Building envelope assemblies and materials.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... MULTI-FAMILY HIGH RISE RESIDENTIAL BUILDINGS Building Design Requirements-Electric Systems and Equipment... be determined with due consideration of all major series and parallel heat flow paths through the... thermal transmittance of opaque elements of assemblies shall be determined using a series path procedure...

  5. 10 CFR 434.402 - Building envelope assemblies and materials.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... MULTI-FAMILY HIGH RISE RESIDENTIAL BUILDINGS Building Design Requirements-Electric Systems and Equipment... be determined with due consideration of all major series and parallel heat flow paths through the... thermal transmittance of opaque elements of assemblies shall be determined using a series path procedure...

  6. 10 CFR 434.402 - Building envelope assemblies and materials.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... MULTI-FAMILY HIGH RISE RESIDENTIAL BUILDINGS Building Design Requirements-Electric Systems and Equipment... be determined with due consideration of all major series and parallel heat flow paths through the... thermal transmittance of opaque elements of assemblies shall be determined using a series path procedure...

  7. 10 CFR 434.402 - Building envelope assemblies and materials.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... MULTI-FAMILY HIGH RISE RESIDENTIAL BUILDINGS Building Design Requirements-Electric Systems and Equipment... be determined with due consideration of all major series and parallel heat flow paths through the... thermal transmittance of opaque elements of assemblies shall be determined using a series path procedure...

  8. 10 CFR 434.402 - Building envelope assemblies and materials.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... MULTI-FAMILY HIGH RISE RESIDENTIAL BUILDINGS Building Design Requirements-Electric Systems and Equipment... be determined with due consideration of all major series and parallel heat flow paths through the... thermal transmittance of opaque elements of assemblies shall be determined using a series path procedure...

  9. Supramolecular Lego assembly towards three-dimensional multi-responsive hydrogels.

    PubMed

    Ma, Chunxin; Li, Tiefeng; Zhao, Qian; Yang, Xuxu; Wu, Jingjun; Luo, Yingwu; Xie, Tao

    2014-08-27

    Inspired by the assembly of Lego toys, hydrogel building blocks with heterogeneous responsiveness are assembled utilizing macroscopic supramolecular recognition as the adhesion force. The Lego hydrogel provides 3D transformation upon pH variation. After disassembly of the building blocks by changing the oxidation state, they can be re-assembled into a completely new shape. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. View of debris assembled at the Kennedy Space Center from STS 51-L

    NASA Technical Reports Server (NTRS)

    1986-01-01

    Large portion of the three main engines of the Space Shuttle Orbiter Challenger have been recovered from the floor of the Atlantic Ocean to the east of the Kennedy Space Center. They have been moved to a large storage building to the east of the Logistics Facility at Complex 39. Most of the pieces were recovered by the Coast Guard and Navy following the accident.

  11. 40. ARAIII Prototype assembly and evaluation building ARA630. East end ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    40. ARA-III Prototype assembly and evaluation building ARA-630. East end and south side of building. Camera facing west. Roof railing is part of demolition preparations. Building beyond ARA-622 is ARA-621. In left of view is reactor building. ARA-607 is low-roofed portion, while high-bay portion is ARA-608. Ineel photo no. 3-27. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

  12. Mussel-inspired nano-building block assemblies for mimicking extracellular matrix microenvironments with multiple functions.

    PubMed

    Wang, Zhenming; Jia, Zhanrong; Jiang, Yanan; Li, Pengfei; Han, Lu; Lu, Xiong; Ren, Fuzeng; Wang, Kefeng; Yuan, Huiping

    2017-08-03

    The assembly of nano-building blocks is an effective way to produce artificial extracellular matrix microenvironments with hierarchical micro/nano structures. However, it is hard to assemble different types of nano-building blocks, to form composite coatings with multiple functions, by traditional layer-by-layer (LbL) self-assembly methods. Inspired by the mussel adhesion mechanism, we developed polydopamine (PDA)-decorated bovine serum albumin microspheres (BSA-MS) and nano-hydroxyapatite (nano-HA), and assembled them to form bioactive coatings with micro/nano structures encapsulating bone morphogenetic protein-2 (BMP-2). First, PDA-decorated nano-HA (nano-pHA) was obtained by oxidative polymerization of dopamine on nano-HA. Second, BMP-2-encapsulated BSA microspheres were prepared through desolvation, and then were also decorated by PDA (pBSA-MS). Finally, the nano-pHA and pBSA-MS were assembled using the adhesive properties of PDA. Bone marrow stromal cell cultures and in vivo implantation, showed that the pHA/pBSA (BMP-2) coatings can promote cell adhesion, proliferation, and benefited for osteoinductivity. PDA decoration was also applied to assemble various functional nanoparticles, such as nano-HA, polystyrene, and Fe 3 O 4 nanoparticles. In summary, this study provides a novel strategy for the assembly of biofunctional nano-building blocks, which surpasses traditional LbL self-assembly of polyelectrolytes, and can find broad applications in bioactive agents delivery or multi-functional coatings.

  13. 49. Neg. No. 7268C, ca. 1930, PhotographerUnknown, OVERALL VIEW OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    49. Neg. No. 7268C, ca. 1930, Photographer-Unknown, OVERALL VIEW OF THE FORD MOTOR COMPANY ASSEMBLY PLANT FROM THE HENRY FORD BRIDGE, PRIOR TO CONSTRUCTION OF THE PRESSED STEEL BUILDING - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  14. 78 FR 47426 - Virgil C. Summer Nuclear Station, Units 2 and 3; South Carolina Electric and Gas; Change to the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-05

    ... Additional Electrical Penetration Assemblies AGENCY: Nuclear Regulatory Commission. ACTION: Exemption and... requested adding four electrical penetration assemblies to the containment vessel and shield building in... assemblies to containment and the shield building. As part of this request, the licensee needed to change...

  15. Effective Light Directed Assembly of Building Blocks with Microscale Control.

    PubMed

    Dinh, Ngoc-Duy; Luo, Rongcong; Christine, Maria Tankeh Asuncion; Lin, Weikang Nicholas; Shih, Wei-Chuan; Goh, James Cho-Hong; Chen, Chia-Hung

    2017-06-01

    Light-directed forces have been widely used to pattern micro/nanoscale objects with precise control, forming functional assemblies. However, a substantial laser intensity is required to generate sufficient optical gradient forces to move a small object in a certain direction, causing limited throughput for applications. A high-throughput light-directed assembly is demonstrated as a printing technology by introducing gold nanorods to induce thermal convection flows that move microparticles (diameter = 40 µm to several hundreds of micrometers) to specific light-guided locations, forming desired patterns. With the advantage of effective light-directed assembly, the microfluidic-fabricated monodispersed biocompatible microparticles are used as building blocks to construct a structured assembly (≈10 cm scale) in ≈2 min. The control with microscale precision is approached by changing the size of the laser light spot. After crosslinking assembly of building blocks, a novel soft material with wanted pattern is approached. To demonstrate its application, the mesenchymal stem-cell-seeded hydrogel microparticles are prepared as functional building blocks to construct scaffold-free tissues with desired structures. This light-directed fabrication method can be applied to integrate different building units, enabling the bottom-up formation of materials with precise control over their internal structure for bioprinting, tissue engineering, and advanced manufacturing. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. KSC-2009-3586

    NASA Image and Video Library

    2009-06-08

    CAPE CANAVERAL, Fla. – The Ares I-X aft skirt moves past the Vehicle Assembly Building at NASA's Kennedy Space Center in Florida on its way to the Rotation, Processing and Surge Facility. In the RPSF, it will be stacked with the aft motor to form the aft assembly. The complete Ares I-X will be assembled in the Vehicle Assembly Building. The launch of Ares I-X is targeted for August 2009. Photo credit: NASA/Jim Grossmann

  17. KSC-2009-3587

    NASA Image and Video Library

    2009-06-08

    CAPE CANAVERAL, Fla. – The Ares I-X aft skirt moves past the Vehicle Assembly Building at NASA's Kennedy Space Center in Florida on its way to the Rotation, Processing and Surge Facility. In the RPSF, it will be stacked with the aft motor to form the aft assembly. The complete Ares I-X will be assembled in the Vehicle Assembly Building. The launch of Ares I-X is targeted for August 2009. Photo credit: NASA/Jim Grossmann

  18. Computational Design of Self-Assembling Protein Nanomaterials with Atomic Level Accuracy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    King, Neil P.; Sheffler, William; Sawaya, Michael R.

    2015-09-17

    We describe a general computational method for designing proteins that self-assemble to a desired symmetric architecture. Protein building blocks are docked together symmetrically to identify complementary packing arrangements, and low-energy protein-protein interfaces are then designed between the building blocks in order to drive self-assembly. We used trimeric protein building blocks to design a 24-subunit, 13-nm diameter complex with octahedral symmetry and a 12-subunit, 11-nm diameter complex with tetrahedral symmetry. The designed proteins assembled to the desired oligomeric states in solution, and the crystal structures of the complexes revealed that the resulting materials closely match the design models. The method canmore » be used to design a wide variety of self-assembling protein nanomaterials.« less

  19. 22. Launch Area, Missile Assembly Building VIEW SOUTHWEST, EAST AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. Launch Area, Missile Assembly Building VIEW SOUTHWEST, EAST AND NORTH ELEVATION - NIKE Missile Battery PR-79, Launch Area, East Windsor Road south of State Route 101, Foster, Providence County, RI

  20. 20. Launch Area, Missile Assembly Building VIEW SOUTHEAST, NORTH AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. Launch Area, Missile Assembly Building VIEW SOUTHEAST, NORTH AND WEST ELEVATION - NIKE Missile Battery PR-79, Launch Area, East Windsor Road south of State Route 101, Foster, Providence County, RI

  1. 21. Launch Area, Missile Assembly Building VIEW NORTHWEST, SOUTH AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. Launch Area, Missile Assembly Building VIEW NORTHWEST, SOUTH AND EAST ELEVATION - NIKE Missile Battery PR-79, Launch Area, East Windsor Road south of State Route 101, Foster, Providence County, RI

  2. 110. NORTH PLANT RAILROAD SPUR, WITH ASSEMBLY PLANT/WAREHOUSE (BUILDING 1601/1606/1701) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    110. NORTH PLANT RAILROAD SPUR, WITH ASSEMBLY PLANT/WAREHOUSE (BUILDING 1601/1606/1701) AT LEFT AND GB MANUFACTURING PLANT (BUILDING 1501) AT CENTER. VIEW TO NORTH. - Rocky Mountain Arsenal, Bounded by Ninety-sixth Avenue & Fifty-sixth Avenue, Buckley Road, Quebec Street & Colorado Highway 2, Commerce City, Adams County, CO

  3. Multicolor emission from large-area porous thin films constructed of nanowires of small organic molecules

    NASA Astrophysics Data System (ADS)

    Wang, Zhe-Chen; Xiao, Wen-Chang; Ding, Xun-Lei; Ma, Yan-Ping; Xue, Wei; He, Sheng-Gui

    2008-12-01

    We describe a facile low-temperature physical vapor deposition approach to fabricate porous network thin films constructed of nanowires of small organic molecules on a large area. Supermolecular assemblies of pyrene nanowires based on a combination of van der Waals forces and π-π stacking tend to hierarchically self-assemble to form uniform porous films using our techniques. The morphology of the films is studied and we also study several reasons influencing the process of assembly such as evaporation temperature, deposition temperature, and different kinds of substrate. The deposition temperature is determined to be the main reason for hierarchical aggregation. Typically prepared films exhibit unique optical properties, that is, multicolor red-green-blue emissions. This novel method can be applied to other organic molecular systems and may be potentially used to place nanoscaled building blocks directly on solid surfaces for fabricating large-area nanostructure-based flat screens.

  4. Supramolecular macrocycles reversibly assembled by Te…O chalcogen bonding

    PubMed Central

    Ho, Peter C.; Szydlowski, Patrick; Sinclair, Jocelyn; Elder, Philip J. W.; Kübel, Joachim; Gendy, Chris; Lee, Lucia Myongwon; Jenkins, Hilary; Britten, James F.; Morim, Derek R.; Vargas-Baca, Ignacio

    2016-01-01

    Organic molecules with heavy main-group elements frequently form supramolecular links to electron-rich centres. One particular case of such interactions is halogen bonding. Most studies of this phenomenon have been concerned with either dimers or infinitely extended structures (polymers and lattices) but well-defined cyclic structures remain elusive. Here we present oligomeric aggregates of heterocycles that are linked by chalcogen-centered interactions and behave as genuine macrocyclic species. The molecules of 3-methyl-5-phenyl-1,2-tellurazole 2-oxide assemble a variety of supramolecular aggregates that includes cyclic tetramers and hexamers, as well as a helical polymer. In all these aggregates, the building blocks are connected by Te…O–N bridges. Nuclear magnetic resonance spectroscopic experiments demonstrate that the two types of annular aggregates are persistent in solution. These self-assembled structures form coordination complexes with transition-metal ions, act as fullerene receptors and host small molecules in a crystal. PMID:27090355

  5. Teaching Assembly for Disassembly; An Under-Graduate Module Experience

    ERIC Educational Resources Information Center

    Alexandri, Eleftheria

    2014-01-01

    This paper is about the experience of teaching Assembly for Disassembly to fourth year architect students within the module of sustainable design. When designing a sustainable building one should take into consideration the fact that the building is going to be demolished in some years; thus the materials should be assembled in such a way so that…

  6. Amyloid-like self-assembly of peptide sequences from the adenovirus fiber shaft: insights from molecular dynamics simulations.

    PubMed

    Tamamis, Phanourios; Kasotakis, Emmanouil; Mitraki, Anna; Archontis, Georgios

    2009-11-26

    The self-assembly of peptides and proteins into nanostructures is related to the fundamental problems of protein folding and misfolding and has potential applications in medicine, materials science and nanotechnology. Natural peptides, corresponding to sequence repeats from self-assembling proteins, may constitute elementary building blocks of such nanostructures. In this work, we study by implicit-solvent replica-exchange simulations the self-assembly of two amyloidogenic sequences derived from the naturally occurring fiber shaft of the adenovirus, the octapeptide NSGAITIG (asparagine-serine-glycine-alanine-isoleucine-threonine-isoleucine-glycine) and its hexapeptide counterpart, GAITIG. In accordance with their amyloidogenic capacity, both peptides form readily intermolecular beta-sheets, stabilized by extensive main- and side-chain contacts involving the C-terminal moieties (segments 3-8 and 2-6, respectively). The structural and energetic properties of these sheets are analyzed extensively. The N-terminal residues Asn1 and Ser2 of the octapeptide remain disordered in the sheets, suggesting that these residues are exposed at the exterior of the fibrils and accessible. On the basis of insight provided by the simulations, cysteine residues were recently substituted at positions 1 and 2 of NSGAITIG; the newly designed peptides maintain their amyloidogenic properties and can bind to silver, gold and platinum nanoparticles [Kasotakis et al. Biopolymers 2009, 92, 164-172]. Computational investigation can identify suitable positions for rational modification of peptide building blocks, aiming at the fabrication of novel biomaterials.

  7. Ion Diffusion-Directed Assembly Approach to Ultrafast Coating of Graphene Oxide Thick Multilayers.

    PubMed

    Zhao, Xiaoli; Gao, Weiwei; Yao, Weiquan; Jiang, Yanqiu; Xu, Zhen; Gao, Chao

    2017-10-24

    The layer-by-layer (LbL) assembly approach has been widely used to fabricate multilayer coatings on substrates with multiple cycles, whereas it is hard to access thick films efficiently. Here, we developed an ion diffusion-directed assembly (IDDA) strategy to rapidly make multilayer thick coatings in one step on arbitrary substrates. To achieve multifunctional coatings, graphene oxide (GO) and metallic ions were selected as the typical building blocks and diffusion director in IDDA, respectively. With diffusion of metallic ions from substrate to negatively charged GO dispersion spontaneously (i.e., from high-concentration region to low-concentration region), GO was assembled onto the substrate sheet-by-sheet via sol-gel transformation. Because metallic ions with size of subnanometers can diffuse directionally and freely in the aqueous dispersion, GO was coated on the substrate efficiently, giving rise to films with desired thickness up to 10 μm per cycle. The IDDA approach shows three main merits: (1) high efficiency with a μm-scale coating rate; (2) controllability over thickness and evenness; and (3) generality for substrates of plastics, metals and ceramics with any shapes and morphologies. With these merits, IDDA strategy was utilized in the efficient fabrication of functional graphene coatings that exhibit outstanding performance as supercapacitors, electromagnetic interference shielding textiles, and anticorrosion coatings. This IDDA approach can be extended to other building blocks including polymers and colloidal nanoparticles, promising for the scalable production and application of multifunctional coatings.

  8. Saturn Apollo Program

    NASA Image and Video Library

    1968-10-01

    The Saturn IB and Saturn V flight vehicles first stages were manufactured at the Michoud Assembly Facility located 24 kilometers (approximately 15 miles) east of downtown New Orleans, Louisiana. The basic manufacturing building boasted 43 acres under one roof. By 1964, NASA added a separate engineering and office building, vertical assembly building, and test stage building. By 1966, other changes to the site included enlarged barge facilities and other miscellaneous support buildings. The image is a view of various vehicle components in the manufacturing plant.

  9. 42. ARAIII Prototype assembly and evaluation building ARA630 interior. Typical ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    42. ARA-III Prototype assembly and evaluation building ARA-630 interior. Typical view room partitions. Ineel photo no. 3-28. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

  10. 24. Launch Area, Missile Assembly Building, detail of original work ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    24. Launch Area, Missile Assembly Building, detail of original work cabinets VIEW NORTHWEST - NIKE Missile Battery PR-79, Launch Area, East Windsor Road south of State Route 101, Foster, Providence County, RI

  11. Ancient techniques for new materials

    NASA Technical Reports Server (NTRS)

    2000-01-01

    NASA is looking to biological techniques that are millions of years old to help it develop new materials and technologies for the 21st century. Sponsored by NASA, Jeffrey Brinker of the University of New Mexico is studying how multiple elements can assemble themselves into a composite material that is clear, tough, and impermeable. His research is based on the model of how an abalone builds the nacre, also called mother-of-pearl, inside its shell. The mollusk layers bricks of calcium carbonate (the main ingredient in classroom chalk) and mortar of biopolymer to form a new material (top and bottom left) that is twice as hard and 1,000 times as tough as either of the original building materials.

  12. Microgravity

    NASA Image and Video Library

    2000-12-15

    NASA is looking to biological techniques that are millions of years old to help it develop new materials and technologies for the 21st century. Sponsored by NASA, Jeffrey Brinker of the University of New Mexico is studying how multiple elements can assemble themselves into a composite material that is clear, tough, and impermeable. His research is based on the model of how an abalone builds the nacre, also called mother-of-pearl, inside its shell. The mollusk layers bricks of calcium carbonate (the main ingredient in classroom chalk) and mortar of biopolymer to form a new material (top and bottom left) that is twice as hard and 1,000 times as tough as either of the original building materials.

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    This is the report on Task IB, Familiarization with Additional Data Collection Plans of Annual Survey of BOMA Member and Non-Member Buildings in 20 Cities, of the Energy Use in Office Buildings project. The purpose of the work was to monitor and understand the efforts of the Building Owners and Managers Association International (BOMA) in gathering an energy-use-oriented data base. In order to obtain an improved data base encompassing a broad spectrum of office space and with information suitable for energy analysis in greater detail than is currently available, BOMA undertook a major data-collection effort. Based on a consideration ofmore » geographic area, climate, population, and availability of data, BOMA selected twenty cities for data collection. BOMA listed all of the major office space - buildings in excess of 40,000 square feet - in each of the cities. Tax-assessment records, local maps, Chamber of Commerce data, recent industrial-development programs, results of related studies, and local-realtor input were used in an effort to assemble a comprehensive office-building inventory. In order to verify the accuracy and completeness of the building lists, BOMA assembled an Ad-Hoc Review Committee in each city to review the assembled inventory of space. A questionnaire on office-building energy use and building characteristics was developed. In each city BOMA assembled a data collection team operating under the supervision of its regional affiliate to gather the data. For each city a random sample of buildings was selected, and data were gathered. Responses for over 1000 buildings were obtained.« less

  14. Photovoltaic sheathing element with a flexible connector assembly

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Langmaid, Joseph A; Keenihan, James R; Mills, Michael E

    2016-07-12

    The present invention is premised upon an assembly including at least a photovoltaic sheathing element capable of being affixed on a building structure, the sheathing element including at least: a photovoltaic cell assembly, a body portion attached to one or more portions of the photovoltaic cell assembly; at least a first and a second connector assembly disposed on opposing sides of the sheathing element and capable of directly or indirectly electrically connecting the photovoltaic cell assembly to at least two adjoining devices that are affixed to the building structure and wherein at least one of the connector assemblies includes amore » flexible portion; one or more connector pockets disposed in the body portion the pockets capable of receiving at least a portion of the connector assembly.« less

  15. Close up view under the Orbiter Discovery in the Vehicle ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Close up view under the Orbiter Discovery in the Vehicle Assembly Building at NASA's Kennedy Space Center. The view is under the port wing looking forward toward the main fuselage showing a detail of the landing gear and landing gear door. This view also shows the patterns of worn and replaced High-temperature Reusable Surface Insulation tiles. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  16. PBF Reactor Building (PER620). Fuel rod test assembly is on ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PBF Reactor Building (PER-620). Fuel rod test assembly is on display at PBF. Date: 1982. INEEL negative no. 82-4893 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

  17. Draft Genome Sequences of 12 Dry-Heat-Resistant Bacillus Strains Isolated from the Cleanrooms Where the Viking Spacecraft Were Assembled

    PubMed Central

    Seuylemezian, Arman; Cooper, Kerry; Schubert, Wayne

    2018-01-01

    ABSTRACT Spore-forming microorganisms are of concern for forward contamination because they can survive harsh interplanetary travel. Here, we report the draft genome sequences of 12 spore-forming strains isolated from the Manned Spacecraft Operations Building (MSOB) and the Vehicle Assembly Building (VAB) in Cape Canaveral, FL, where the Viking spacecraft were assembled. PMID:29567731

  18. Multicomponent self-assembly as a tool to harness new properties from peptides and proteins in material design.

    PubMed

    Okesola, Babatunde O; Mata, Alvaro

    2018-05-21

    Nature is enriched with a wide variety of complex, synergistic, and highly functional protein-based multicomponent assemblies. As such, nature has served as a source of inspiration for using multicomponent self-assembly as a platform to create highly ordered, complex, and dynamic protein and peptide-based nanostructures. Such an assembly system relies on the initial interaction of distinct individual building blocks leading to the formation of a complex that subsequently assembles into supramolecular architectures. This approach not only serves as a powerful platform for gaining insight into how proteins co-assemble in nature but also offers huge opportunities to harness new properties not inherent in the individual building blocks. In the past decades, various multicomponent self-assembly strategies have been used to extract synergistic properties from proteins and peptides. This review highlights the updates in the field of multicomponent self-assembly of proteins and peptides and summarizes various strategies, including covalent conjugation, ligand-receptor interactions, templated/directed assembly and non-specific co-assembly, for driving the self-assembly of multiple proteins and peptide-based building blocks into functional materials. In particular, we focus on peptide- or protein-containing multicomponent systems that, upon self-assembly, enable the emergence of new properties or phenomena. The ultimate goal of this review is to highlight the importance of multicomponent self-assembly in protein and peptide engineering, and to advocate its growth in the fields of materials science and nanotechnology.

  19. Gigadalton-scale shape-programmable DNA assemblies

    NASA Astrophysics Data System (ADS)

    Wagenbauer, Klaus F.; Sigl, Christian; Dietz, Hendrik

    2017-12-01

    Natural biomolecular assemblies such as molecular motors, enzymes, viruses and subcellular structures often form by self-limiting hierarchical oligomerization of multiple subunits. Large structures can also assemble efficiently from a few components by combining hierarchical assembly and symmetry, a strategy exemplified by viral capsids. De novo protein design and RNA and DNA nanotechnology aim to mimic these capabilities, but the bottom-up construction of artificial structures with the dimensions and complexity of viruses and other subcellular components remains challenging. Here we show that natural assembly principles can be combined with the methods of DNA origami to produce gigadalton-scale structures with controlled sizes. DNA sequence information is used to encode the shapes of individual DNA origami building blocks, and the geometry and details of the interactions between these building blocks then control their copy numbers, positions and orientations within higher-order assemblies. We illustrate this strategy by creating planar rings of up to 350 nanometres in diameter and with atomic masses of up to 330 megadaltons, micrometre-long, thick tubes commensurate in size to some bacilli, and three-dimensional polyhedral assemblies with sizes of up to 1.2 gigadaltons and 450 nanometres in diameter. We achieve efficient assembly, with yields of up to 90 per cent, by using building blocks with validated structure and sufficient rigidity, and an accurate design with interaction motifs that ensure that hierarchical assembly is self-limiting and able to proceed in equilibrium to allow for error correction. We expect that our method, which enables the self-assembly of structures with sizes approaching that of viruses and cellular organelles, can readily be used to create a range of other complex structures with well defined sizes, by exploiting the modularity and high degree of addressability of the DNA origami building blocks used.

  20. Gigadalton-scale shape-programmable DNA assemblies.

    PubMed

    Wagenbauer, Klaus F; Sigl, Christian; Dietz, Hendrik

    2017-12-06

    Natural biomolecular assemblies such as molecular motors, enzymes, viruses and subcellular structures often form by self-limiting hierarchical oligomerization of multiple subunits. Large structures can also assemble efficiently from a few components by combining hierarchical assembly and symmetry, a strategy exemplified by viral capsids. De novo protein design and RNA and DNA nanotechnology aim to mimic these capabilities, but the bottom-up construction of artificial structures with the dimensions and complexity of viruses and other subcellular components remains challenging. Here we show that natural assembly principles can be combined with the methods of DNA origami to produce gigadalton-scale structures with controlled sizes. DNA sequence information is used to encode the shapes of individual DNA origami building blocks, and the geometry and details of the interactions between these building blocks then control their copy numbers, positions and orientations within higher-order assemblies. We illustrate this strategy by creating planar rings of up to 350 nanometres in diameter and with atomic masses of up to 330 megadaltons, micrometre-long, thick tubes commensurate in size to some bacilli, and three-dimensional polyhedral assemblies with sizes of up to 1.2 gigadaltons and 450 nanometres in diameter. We achieve efficient assembly, with yields of up to 90 per cent, by using building blocks with validated structure and sufficient rigidity, and an accurate design with interaction motifs that ensure that hierarchical assembly is self-limiting and able to proceed in equilibrium to allow for error correction. We expect that our method, which enables the self-assembly of structures with sizes approaching that of viruses and cellular organelles, can readily be used to create a range of other complex structures with well defined sizes, by exploiting the modularity and high degree of addressability of the DNA origami building blocks used.

  1. Vented Cavity Radiant Barrier Assembly And Method

    DOEpatents

    Dinwoodie, Thomas L.; Jackaway, Adam D.

    2000-05-16

    A vented cavity radiant barrier assembly (2) includes a barrier (12), typically a PV module, having inner and outer surfaces (18, 22). A support assembly (14) is secured to the barrier and extends inwardly from the inner surface of the barrier to a building surface (14) creating a vented cavity (24) between the building surface and the barrier inner surface. A low emissivity element (20) is mounted at or between the building surface and the barrier inner surface. At least part of the cavity exit (30) is higher than the cavity entrance (28) to promote cooling air flow through the cavity.

  2. Draft Genome Sequences of 12 Dry-Heat-Resistant Bacillus Strains Isolated from the Cleanrooms Where the Viking Spacecraft Were Assembled.

    PubMed

    Seuylemezian, Arman; Cooper, Kerry; Schubert, Wayne; Vaishampayan, Parag

    2018-03-22

    Spore-forming microorganisms are of concern for forward contamination because they can survive harsh interplanetary travel. Here, we report the draft genome sequences of 12 spore-forming strains isolated from the Manned Spacecraft Operations Building (MSOB) and the Vehicle Assembly Building (VAB) in Cape Canaveral, FL, where the Viking spacecraft were assembled. Copyright © 2018 Seuylemezian et al.

  3. 48. Neg. No. P3120, ca. 1930, Photographer A. C. Gates, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    48. Neg. No. P-3120, ca. 1930, Photographer- A. C. Gates, Los Angeles, AERIAL VIEW OF THE FORD MOTOR COMPANY ASSEMBLY PLANT, PRIOR TO CONSTRUCTION OF THE PRESSED STEEL BUILDING, NOTE THE CLIPPER SHIPS IN THE BACKGROUND, AND THE OIL WELLS IN THE UPPER LEFT CORNER - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  4. PBF Reactor Building (PER620). PBF crane holds fuel test assembly ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PBF Reactor Building (PER-620). PBF crane holds fuel test assembly aloft prior to lowering into reactor for test. Date: 1982. INEEL negative no. 82-4909 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

  5. INTERIOR VIEW OF FUEL STORAGE BUILDING (CPP603) SHOWING CRANE ASSEMBLY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    INTERIOR VIEW OF FUEL STORAGE BUILDING (CPP-603) SHOWING CRANE ASSEMBLY FOR TRANSFER PIT. INL PHOTO NUMBER NRTS-51-2404. Unknown Photographer, 5/31/1951 - Idaho National Engineering Laboratory, Idaho Chemical Processing Plant, Fuel Reprocessing Complex, Scoville, Butte County, ID

  6. Saturn Apollo Program

    NASA Image and Video Library

    1967-11-01

    This image depicts a Boeing worker installing an F-1 engine on the Saturn V S-IC flight stage at the Michoud Assembly Facility (MAF). The Saturn IB and Saturn V first stages were manufactured at the MAF, located 24 kilometers (approximately 15 miles) east of downtown New Orleans, Louisiana. The prime contractors, Chrysler and Boeing, jointly occupied the MAF. The basic manufacturing building boasted 43 acres under one roof. By 1964, NASA added a separate engineering and office building, vertical assembly building, and test stage building.

  7. DNA-templated photonic arrays and assemblies: design principles and future opportunities.

    PubMed

    Su, Wu; Bonnard, Vanessa; Burley, Glenn A

    2011-07-11

    Molecular photonics is a rapidly developing and multi-disciplinary field of research involving the construction of molecular assemblies comprising photoactive building blocks that are responsive to a light stimulus. A salient challenge in this field is the controlled assembly of these building blocks with nanoscale precision. DNA exhibits considerable promise as an architecture for the templated assembly of photoactive materials. In this Concept Article we describe the progress that has been made in the area of DNA photonics, in which DNA acts as a platform for the construction of optoelectronic assemblies, thin films and devices. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. 36. ASSEMBLY LINE AREA FROM NEAR INTERIOR LOADING DOCK. VIEW ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    36. ASSEMBLY LINE AREA FROM NEAR INTERIOR LOADING DOCK. VIEW TO WEST-NORTHWEST. - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  9. KSC-2010-4579

    NASA Image and Video Library

    2010-09-08

    CAPE CANAVERAL, Fla. -- In the LC-39 Complex Turn Basin area across from the Vehicle Assembly Building at NASA's Kennedy Space Center in Florida, a major water main leak in a 24-inch pipe caused soil to wash away near the Press Site. The center was closed for the morning while workers assessed and repaired the break. In the background is the Pegasus barge docked at the Turn Basin which is used to deliver the space shuttle external fuel tank. Photo credit: NASA/Jack Pfaller

  10. KSC-2010-4582

    NASA Image and Video Library

    2010-09-08

    CAPE CANAVERAL, Fla. -- In the LC-39 Complex Turn Basin area across from the Vehicle Assembly Building at NASA's Kennedy Space Center in Florida, a major water main leak in a 24-inch pipe caused soil to wash away near the Press Site. The center was closed for the morning while workers assessed and repaired the break. In the background is the Pegasus barge docked at the Turn Basin which is used to deliver the space shuttle external fuel tank. Photo credit: NASA/Jack Pfaller

  11. KSC-2010-4580

    NASA Image and Video Library

    2010-09-08

    CAPE CANAVERAL, Fla. -- In the LC-39 Complex Turn Basin area across from the Vehicle Assembly Building at NASA's Kennedy Space Center in Florida, a major water main leak in a 24-inch pipe caused soil to wash away near the Press Site. The center was closed for the morning while workers assessed and repaired the break. In the background is the Pegasus barge docked at the Turn Basin which is used to deliver the space shuttle external fuel tank. Photo credit: NASA/Jack Pfaller

  12. KSC00pp1955

    NASA Image and Video Library

    2000-12-11

    Members of the crew of the television series This Old House get a close look at one of the main engines on Space Shuttle Atlantis in the Vehicle Assembly Building. At left is Norm Abram, master carpenter on the series. Next to him is Steve Thomas, host of the show. At the far right is astronaut John Herrington, who is accompanying the film crew on their tour of KSC. The cast and crew of This Old House are filming at KSC for an episode of the show

  13. Environmental Assessment Supplement: Proposed Military Construction Project, Deployable Medical System Training Area and Military Equipment Parking, Fairchild Air Force Base, Washington

    DTIC Science & Technology

    2011-11-01

    considered semi-improved and mowed four times a year. The site is treated twice a year with herbicides to control invasive pest plants: diffuse...According to the Fairchild AFB Pest Management Plan, contractors mix all pesticide and herbicide chemicals off-base (92 CES/CEAN, 2007...1) Armed Forces Reserve Center (AFRC) – A main building approximately 80,900 square feet (s.f.) for office space, assembly hall with kitchen

  14. General view of the aft section of the Orbiter Discovery ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of the aft section of the Orbiter Discovery in the Vehicle Assembly Building at NASA's Kennedy Space Center. Note the main engines and Orbiter Maneuvering System/Reaction Control System pods are removed in this photo. The flexible hoses protruding from the starboard aft section are to control temperature, humidity and pressure in the orbiter's void spaces during its down time. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  15. General view of the aft, starboard section of the Orbiter ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of the aft, starboard section of the Orbiter Discovery in the Vehicle Assembly Building at NASA's Kennedy Space Center. Note the main engines and Orbiter Maneuvering System/Reaction Control System pods are removed in this photo. The flexible hoses protruding from the starboard aft section are to control temperature, humidity and pressure in the orbiter's void spaces during its down time. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  16. KSC-99pp0199

    NASA Image and Video Library

    1999-02-09

    KENNEDY SPACE CENTER, FLA. -- An external tank is suspended in the transfer aisle of the Vehicle Assembly Building before being placed into its storage compartment. The largest and heaviest element of the Space Shuttle, an external tank contains the liquid hydrogen fuel and liquid oxygen oxidizer for the three Space Shuttle main engines (SSMEs) in the orbiter during liftoff and ascent. When the SSMEs are shut down, the external tank is jettisoned, breaking up as it enters the Earth's atmopshere and impacting in a remote ocean area. It is not recovered

  17. Vehicle Assembly Building In The Rain

    NASA Image and Video Library

    2009-07-09

    The NASA Vehicle Assembly Building is seen through a rain covered windshield at NASA's Kennedy Space Center in Florida on Friday, July 10, 2009. NASA is set to launch the space shuttle Endeavour with the crew of STS-127 on Saturday. Photo Credit: (NASA/Bill Ingalls)

  18. First stage of Saturn launch vehicle in KSC Vehicle Assembly Building

    NASA Technical Reports Server (NTRS)

    1968-01-01

    The first (S-1C) stage of the Saturn 505 launch vehicle being prepared for erection in the high bay area of the Kennedy Space Center's (KSC) Vehicle Assembly Building (VAB). Saturn 505 is the launch vehicle for the Apollo 10 mission.

  19. 20. Interior of assembly building (mold loft #2) used for ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. Interior of assembly building (mold loft #2) used for runabout production-woodworking shop. Note counter-weighted vertical sliding doors along wall to left to move materials and boats to other room. - Barbour Boat Works, Tryon Palace Drive, New Bern, Craven County, NC

  20. KSC-98pc786

    NASA Image and Video Library

    1998-07-06

    James W. Tibble (pointing at engine), an Engine Systems/Ground Support Equipment team manager for Rocketdyne, discusses the operation of a Space Shuttle Main Engine with Robert B. Sieck, director of Shuttle Processing; U.S. Congressman Dave Weldon; and KSC Center Director Roy D. Bridges Jr. Following the ribbon cutting ceremony for KSC's new 34,600-square-foot Space Shuttle Main Engine Processing Facility (SSMEPF), KSC employees and media explored the facility. A major addition to the existing Orbiter Processing Facility Bay 3, the SSMEPF replaces the Shuttle Main Engine Shop located in the Vehicle Assembly Building (VAB). The decision to move the shop out of the VAB was prompted by safety considerations and recent engine processing improvements. The first three main engines to be processed in the new facility will fly on Shuttle Endeavour's STS-88 mission in December 1998

  1. The SSMEPF opens with a ribbon-cutting ceremony

    NASA Technical Reports Server (NTRS)

    1998-01-01

    James W. Tibble (pointing at engine), an Engine Systems/Ground Support Equipment team manager for Rocketdyne, discusses the operation of a Space Shuttle Main Engine with Robert B. Sieck, director of Shuttle Processing; U.S. Congressman Dave Weldon; and KSC Center Director Roy D. Bridges Jr. Following the ribbon cutting ceremony for KSC's new 34,600-square-foot Space Shuttle Main Engine Processing Facility (SSMEPF), KSC employees and media explored the facility. A major addition to the existing Orbiter Processing Facility Bay 3, the SSMEPF replaces the Shuttle Main Engine Shop located in the Vehicle Assembly Building (VAB). The decision to move the shop out of the VAB was prompted by safety considerations and recent engine processing improvements. The first three main engines to be processed in the new facility will fly on Shuttle Endeavour's STS-88 mission in December 1998.

  2. A model for the sustainable selection of building envelope assemblies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huedo, Patricia, E-mail: huedo@uji.es; Mulet, Elena, E-mail: emulet@uji.es; López-Mesa, Belinda, E-mail: belinda@unizar.es

    2016-02-15

    The aim of this article is to define an evaluation model for the environmental impacts of building envelopes to support planners in the early phases of materials selection. The model is intended to estimate environmental impacts for different combinations of building envelope assemblies based on scientifically recognised sustainability indicators. These indicators will increase the amount of information that existing catalogues show to support planners in the selection of building assemblies. To define the model, first the environmental indicators were selected based on the specific aims of the intended sustainability assessment. Then, a simplified LCA methodology was developed to estimate themore » impacts applicable to three types of dwellings considering different envelope assemblies, building orientations and climate zones. This methodology takes into account the manufacturing, installation, maintenance and use phases of the building. Finally, the model was validated and a matrix in Excel was created as implementation of the model. - Highlights: • Method to assess the envelope impacts based on a simplified LCA • To be used at an earlier phase than the existing methods in a simple way. • It assigns a score by means of known sustainability indicators. • It estimates data about the embodied and operating environmental impacts. • It compares the investment costs with the costs of the consumed energy.« less

  3. Automated assembly of oligosaccharides containing multiple cis-glycosidic linkages

    NASA Astrophysics Data System (ADS)

    Hahm, Heung Sik; Hurevich, Mattan; Seeberger, Peter H.

    2016-09-01

    Automated glycan assembly (AGA) has advanced from a concept to a commercial technology that rapidly provides access to diverse oligosaccharide chains as long as 30-mers. To date, AGA was mainly employed to incorporate trans-glycosidic linkages, where C2 participating protecting groups ensure stereoselective couplings. Stereocontrol during the installation of cis-glycosidic linkages cannot rely on C2-participation and anomeric mixtures are typically formed. Here, we demonstrate that oligosaccharides containing multiple cis-glycosidic linkages can be prepared efficiently by AGA using monosaccharide building blocks equipped with remote participating protecting groups. The concept is illustrated by the automated syntheses of biologically relevant oligosaccharides bearing various cis-galactosidic and cis-glucosidic linkages. This work provides further proof that AGA facilitates the synthesis of complex oligosaccharides with multiple cis-linkages and other biologically important oligosaccharides.

  4. Opal-like Multicolor Appearance of Self-Assembled Photonic Array.

    PubMed

    Arnon, Zohar A; Pinotsi, Dorothea; Schmidt, Matthias; Gilead, Sharon; Guterman, Tom; Sadhanala, Aditya; Ahmad, Shahab; Levin, Aviad; Walther, Paul; Kaminski, Clemens F; Fändrich, Marcus; Kaminski Schierle, Gabriele S; Adler-Abramovich, Lihi; Shimon, Linda J W; Gazit, Ehud

    2018-06-20

    Molecular self-assembly of short peptide building blocks leads to the formation of various material architectures that may possess unique physical properties. Recent studies had confirmed the key role of biaromaticity in peptide self-assembly, with the diphenylalanine (FF) structural family as an archetypal model. Another significant direction in the molecular engineering of peptide building blocks is the use of fluorenylmethoxycarbonyl (Fmoc) modification, which promotes the assembly process and may result in nanostructures with distinctive features and macroscopic hydrogel with supramolecular features and nanoscale order. Here, we explored the self-assembly of the protected, noncoded fluorenylmethoxycarbonyl-β,β-diphenyl-Ala-OH (Fmoc-Dip) amino acid. This process results in the formation of elongated needle-like crystals with notable aromatic continuity. By altering the assembly conditions, arrays of spherical particles were formed that exhibit strong light scattering. These arrays display vivid coloration, strongly resembling the appearance of opal gemstones. However, unlike the Rayleigh scattering effect produced by the arrangement of opal, the described optical phenomenon is attributed to Mie scattering. Moreover, by controlling the solution evaporation rate, i.e., the assembly kinetics, we were able to manipulate the resulting coloration. This work demonstrates a bottom-up approach, utilizing self-assembly of a protected amino acid minimal building block, to create arrays of organic, light-scattering colorful surfaces.

  5. Charge Effect on the Formation of Polyoxometalate-Based Supramolecular Polygons Driven by Metal Coordination.

    PubMed

    Piot, Madeleine; Hupin, Sébastien; Lavanant, Hélène; Afonso, Carlos; Bouteiller, Laurent; Proust, Anna; Izzet, Guillaume

    2017-07-17

    The metal-driven self-assembly of a Keggin-based hybrid bearing two remote pyridine units was investigated. The resulting supramolecular species were identified by combination of 2D diffusion NMR spectroscopy (DOSY) and electrospray ionization mass spectrometry (ESI-MS) as a mixture of molecular triangles and squares. This behavior is different from that of the structural analogue Dawson-based hybrid displaying a higher charge, which only led to the formation of molecular triangles. This study highlights the decisive effect of the charge of the POMs in their self-assembly processes that disfavors the formation of large assemblies. An isothermal titration calorimetry (ITC) experiment confirmed the stronger binding in the case of the Keggin hybrids. A correlation between the diffusion coefficient D and the molecular mass M of the POM-based building block and its coordination oligomers was also observed. We show that the diffusion coefficient of these compounds is mainly determined by their occupied volume rather than by their shape.

  6. Nanoparticles and self-organisation: the emergence of hierarchical properties from the nanoparticle soup (i.e., the small is getting bigger). Concluding remarks for Faraday Discussion: Nanoparticle Synthesis and Assembly.

    PubMed

    Schiffrin, David J

    2015-01-01

    Some four years ago, one of the participants in this Discussion (Prof. Nicholas Kotov) predicted that: "within five years we shall see multiple examples of electronic, sensor, optical and other devices utilizing self-assembled superstructures" (N. A. Kotov, J. Mater. Chem., 2011, 21, 16673-16674). Although this prediction came partially to fruition, we have witnessed an unprecedented interest in the properties of materials at the nanoscale. The point highlighted by Kotov, however, was the importance of self-assembly of structures from well characterised building blocks to yield hierarchical structures, hopefully with predictable properties, a concept that is an everyday pursuit of synthetic chemists. This Discussion has brought together researchers from a wide range of disciplines, i.e., colloid science, modelling, nanoparticle synthesis and organisation, magnetic and optical materials, and new imaging methods, within the excellent traditional Faraday Discussion format, to discuss advances in areas relevant to the main theme of the meeting.

  7. Imaging and Quantitation of a Succession of Transient Intermediates Reveal the Reversible Self-Assembly Pathway of a Simple Icosahedral Virus Capsid.

    PubMed

    Medrano, María; Fuertes, Miguel Ángel; Valbuena, Alejandro; Carrillo, Pablo J P; Rodríguez-Huete, Alicia; Mateu, Mauricio G

    2016-11-30

    Understanding the fundamental principles underlying supramolecular self-assembly may facilitate many developments, from novel antivirals to self-organized nanodevices. Icosahedral virus particles constitute paradigms to study self-assembly using a combination of theory and experiment. Unfortunately, assembly pathways of the structurally simplest virus capsids, those more accessible to detailed theoretical studies, have been difficult to study experimentally. We have enabled the in vitro self-assembly under close to physiological conditions of one of the simplest virus particles known, the minute virus of mice (MVM) capsid, and experimentally analyzed its pathways of assembly and disassembly. A combination of electron microscopy and high-resolution atomic force microscopy was used to structurally characterize and quantify a succession of transient assembly and disassembly intermediates. The results provided an experiment-based model for the reversible self-assembly pathway of a most simple (T = 1) icosahedral protein shell. During assembly, trimeric capsid building blocks are sequentially added to the growing capsid, with pentamers of building blocks and incomplete capsids missing one building block as conspicuous intermediates. This study provided experimental verification of many features of self-assembly of a simple T = 1 capsid predicted by molecular dynamics simulations. It also demonstrated atomic force microscopy imaging and automated analysis, in combination with electron microscopy, as a powerful single-particle approach to characterize at high resolution and quantify transient intermediates during supramolecular self-assembly/disassembly reactions. Finally, the efficient in vitro self-assembly achieved for the oncotropic, cell nucleus-targeted MVM capsid may facilitate its development as a drug-encapsidating nanoparticle for anticancer targeted drug delivery.

  8. 6. SAWTOOTH WINDOW RANKS ABOVE ASSEMBLY LINES, WATER TOWER, AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. SAWTOOTH WINDOW RANKS ABOVE ASSEMBLY LINES, WATER TOWER, AND SECOND FLOOR WAREHOUSE STRUCTURE. VIEW TO SOUTH-SOUTHEAST. - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  9. Building block synthesis using the polymerase chain assembly method.

    PubMed

    Marchand, Julie A; Peccoud, Jean

    2012-01-01

    De novo gene synthesis allows the creation of custom DNA molecules without the typical constraints of traditional cloning assembly: scars, restriction site incompatibility, and the quest to find all the desired parts to name a few. Moreover, with the help of computer-assisted design, the perfect DNA molecule can be created along with its matching sequence ready to download. The challenge is to build the physical DNA molecules that have been designed with the software. Although there are several DNA assembly methods, this section presents and describes a method using the polymerase chain assembly (PCA).

  10. The SSMEPF opens with a ribbon-cutting ceremony

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Participants in the ribbon cutting for KSC's new 34,600-square- foot Space Shuttle Main Engine Processing Facility (SSMEPF) gather to talk inside the facility following the ceremony. From left, they are Robert B. Sieck, director of Shuttle Processing; KSC Center Director Roy D. Bridges Jr.; U.S. Congressman Dave Weldon; John Plowden, vice president of Rocketdyne; and Donald R. McMonagle, manager of Launch Integration. A major addition to the existing Orbiter Processing Facility Bay 3, the SSMEPF replaces the Shuttle Main Engine Shop located in the Vehicle Assembly Building (VAB). The decision to move the shop out of the VAB was prompted by safety considerations and recent engine processing improvements. The first three main engines to be processed in the new facility will fly on Shuttle Endeavour's STS-88 mission in December 1998.

  11. First stage of Saturn launch vehicle in KSC Vehicle Assembly Building

    NASA Image and Video Library

    1968-12-03

    S68-55034 (3 Dec. 1968) --- The first (S-1C) stage of the Saturn 505 launch vehicle being prepared for erection in the high bay area of the Kennedy Space Center's (KSC) Vehicle Assembly Building (VAB). Saturn 505 is the launch vehicle for the Apollo 10 mission.

  12. General view of the interior of the Vehicle Assembly Building ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of the interior of the Vehicle Assembly Building showing the External Tank mated to the Solid Rocket Boosters awaiting the arrival and mating of the Orbiter Discovery. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  13. 57. Neg. No. F161D, Mar 18, 1933, INTERIORPRESSED STEEL AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    57. Neg. No. F-161D, Mar 18, 1933, INTERIOR-PRESSED STEEL AND WAREHOUSE BUILDINGS, 1ST FLOOR, SHOWING DAMAGE TO FREIGHT ELEVATOR SHAFT FROM EARTHQUAKE - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  14. 51. Neg. No. F183E, Mar 16, 1937, EXTERIORFORD ASSEMBLY PLANT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    51. Neg. No. F-183E, Mar 16, 1937, EXTERIOR-FORD ASSEMBLY PLANT EAST SIDE, SHOWING OIL WELL #6 IN THE FOREGROUND, NORTHEAST OF THE ASSEMBLY PLANT - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  15. Research Advances on Fabricated Shear Wall System

    NASA Astrophysics Data System (ADS)

    Liu, Xudong; Wang, Donghui; Wang, Sheng; Zhai, Yu

    2018-03-01

    With the rapid development of the construction industry, building energy consumption has been increasing, has become a problem that can not be ignored. It is imperative to develop energy-saving buildings. A new type of prefabricated shear wall is assembled and partially assembled by prefabricated parts, and some concrete is spliced together. The new structure has good integrity, seismic resistance and excellent energy saving and environmental protection performance. It reduces building energy consumption to a great extent. Therefore, the design method, manufacturing process, site assembly process and key technical problems of the system are discussed. For the construction industry gradually entered the energy conservation, environmental protection, safety and durability of sustainable development laid the foundation.

  16. Invited Article: Autonomous assembly of atomically perfect nanostructures using a scanning tunneling microscope.

    PubMed

    Celotta, Robert J; Balakirsky, Stephen B; Fein, Aaron P; Hess, Frank M; Rutter, Gregory M; Stroscio, Joseph A

    2014-12-01

    A major goal of nanotechnology is to develop the capability to arrange matter at will by placing individual atoms at desired locations in a predetermined configuration to build a nanostructure with specific properties or function. The scanning tunneling microscope has demonstrated the ability to arrange the basic building blocks of matter, single atoms, in two-dimensional configurations. An array of various nanostructures has been assembled, which display the quantum mechanics of quantum confined geometries. The level of human interaction needed to physically locate the atom and bring it to the desired location limits this atom assembly technology. Here we report the use of autonomous atom assembly via path planning technology; this allows atomically perfect nanostructures to be assembled without the need for human intervention, resulting in precise constructions in shorter times. We demonstrate autonomous assembly by assembling various quantum confinement geometries using atoms and molecules and describe the benefits of this approach.

  17. Multi-shape memory polymers achieved by the spatio-assembly of 3D printable thermoplastic building blocks.

    PubMed

    Li, Hongze; Gao, Xiang; Luo, Yingwu

    2016-04-07

    Multi-shape memory polymers were prepared by the macroscale spatio-assembly of building blocks in this work. The building blocks were methyl acrylate-co-styrene (MA-co-St) copolymers, which have the St-block-(St-random-MA)-block-St tri-block chain sequence. This design ensures that their transition temperatures can be adjusted over a wide range by varying the composition of the middle block. The two St blocks at the chain ends can generate a crosslink network in the final device to achieve strong bonding force between building blocks and the shape memory capacity. Due to their thermoplastic properties, 3D printing was employed for the spatio-assembly to build devices. This method is capable of introducing many transition phases into one device and preparing complicated shapes via 3D printing. The device can perform a complex action via a series of shape changes. Besides, this method can avoid the difficult programing of a series of temporary shapes. The control of intermediate temporary shapes was realized via programing the shapes and locations of building blocks in the final device.

  18. 111. DETAIL OF NORTH PLANT RAILROAD SPUR, WITH ASSEMBLY PLANT/WAREHOUSE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    111. DETAIL OF NORTH PLANT RAILROAD SPUR, WITH ASSEMBLY PLANT/WAREHOUSE (BUILDING 1601/1606/1701) AT LEFT AND GB MANUFACTURING PLANT (BUILDING 1501) AT CENTER. VIEW TO NORTH. - Rocky Mountain Arsenal, Bounded by Ninety-sixth Avenue & Fifty-sixth Avenue, Buckley Road, Quebec Street & Colorado Highway 2, Commerce City, Adams County, CO

  19. A laboratory facility for research on wind-driven rain intrusion in building envelope assemblies

    Treesearch

    Samuel V. Glass

    2010-01-01

    Moisture management is critical for durable, energy-efficient buildings. To address the need for research on wind-driven rain intrusion in wall assemblies, the U.S. Forest Products Laboratory is developing a new facility. This paper describes the underlying principle of this facility and its capabilities.

  20. Full Moon with Vehicle Assembly Building and Mobile Launcher

    NASA Image and Video Library

    2018-02-01

    A full Moon sets behind the Vehicle Assembly Building and Mobile Launcher at NASA’s Kennedy Space Center in Florida. At the nation’s premier multi-user spaceport, NASA and its commercial and international partners are looking to return humans to the Moon and beyond utilizing a variety of rockets and capabilities.

  1. APOLLO 4 SATURN V LAUNCH VEHICLE MATING INSIDE VEHICLE ASSEMBLY BUILDING [VAB

    NASA Technical Reports Server (NTRS)

    1967-01-01

    The S II stage of the Apollo/Saturn 501 launch vehicle is being mated to the first stage at the Vehicle Assembly Building [VAB] in preparation for the National Aeronautics and Space Administration's first Saturn V mission. The mission will be unmanned and is scheduled early this year.

  2. Moisture and Structural Analysis for High Performance Hybrid Wall Assemblies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Grin, A.; Lstiburek, J.

    2012-09-01

    This report describes the work conducted by the Building Science Corporation (BSC) Building America Research Team's 'Energy Efficient Housing Research Partnerships' project. Based on past experience in the Building America program, they have found that combinations of materials and approaches---in other words, systems--usually provide optimum performance. No single manufacturer typically provides all of the components for an assembly, nor has the specific understanding of all the individual components necessary for optimum performance.

  3. Total synthesis of TMG-chitotriomycin based on an automated electrochemical assembly of a disaccharide building block.

    PubMed

    Isoda, Yuta; Sasaki, Norihiko; Kitamura, Kei; Takahashi, Shuji; Manmode, Sujit; Takeda-Okuda, Naoko; Tamura, Jun-Ichi; Nokami, Toshiki; Itoh, Toshiyuki

    2017-01-01

    The total synthesis of TMG-chitotriomycin using an automated electrochemical synthesizer for the assembly of carbohydrate building blocks is demonstrated. We have successfully prepared a precursor of TMG-chitotriomycin, which is a structurally-pure tetrasaccharide with typical protecting groups, through the methodology of automated electrochemical solution-phase synthesis developed by us. The synthesis of structurally well-defined TMG-chitotriomycin has been accomplished in 10-steps from a disaccharide building block.

  4. Self-assembly: Misfits unite

    NASA Astrophysics Data System (ADS)

    Grason, Gregory M.

    2017-12-01

    The spontaneous assembly of particulate or molecular 'building blocks' into larger architectures underlies structure formation in many biological and synthetic materials. Shape frustration of ill-fitting blocks holds a surprising key to more regular assemblies.

  5. Assemble: an interactive graphical tool to analyze and build RNA architectures at the 2D and 3D levels.

    PubMed

    Jossinet, Fabrice; Ludwig, Thomas E; Westhof, Eric

    2010-08-15

    Assemble is an intuitive graphical interface to analyze, manipulate and build complex 3D RNA architectures. It provides several advanced and unique features within the framework of a semi-automated modeling process that can be performed by homology and ab initio with or without electron density maps. Those include the interactive editing of a secondary structure and a searchable, embedded library of annotated tertiary structures. Assemble helps users with performing recurrent and otherwise tedious tasks in structural RNA research. Assemble is released under an open-source license (MIT license) and is freely available at http://bioinformatics.org/assemble. It is implemented in the Java language and runs on MacOSX, Linux and Windows operating systems.

  6. 58. MILL BUILDING (BUILDING 1558): VIEW FROM SOUTHWEST, WITH V2 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    58. MILL BUILDING (BUILDING 1558): VIEW FROM SOUTHWEST, WITH V-2 ASSEMBLY BUILDING IN BACKGROUND AT FAR RIGHT - White Sands Missile Range, V-2 Rocket Facilities, Near Headquarters Area, White Sands, Dona Ana County, NM

  7. Noncanonical self-assembly of multifunctional DNA nanoflowers for biomedical applications.

    PubMed

    Zhu, Guizhi; Hu, Rong; Zhao, Zilong; Chen, Zhuo; Zhang, Xiaobing; Tan, Weihong

    2013-11-06

    DNA nanotechnology has been extensively explored to assemble various functional nanostructures for versatile applications. Mediated by Watson-Crick base-pairing, these DNA nanostructures have been conventionally assembled through hybridization of many short DNA building blocks. Here we report the noncanonical self-assembly of multifunctional DNA nanostructures, termed as nanoflowers (NFs), and the versatile biomedical applications. These NFs were assembled from long DNA building blocks generated via rolling circle replication (RCR) of a designer template. NF assembly was driven by liquid crystallization and dense packaging of building blocks, without relying on Watson-Crick base-pairing between DNA strands, thereby avoiding the otherwise conventional complicated DNA sequence design. NF sizes were readily tunable in a wide range, by simply adjusting such parameters as assembly time and template sequences. NFs were exceptionally resistant to nuclease degradation, denaturation, or dissociation at extremely low concentration, presumably resulting from the dense DNA packaging in NFs. The exceptional biostability is critical for biomedical applications. By rational design, NFs can be readily incorporated with myriad functional moieties. All these properties make NFs promising for versatile applications. As a proof-of-principle demonstration, in this study, NFs were integrated with aptamers, bioimaging agents, and drug loading sites, and the resultant multifunctional NFs were demonstrated for selective cancer cell recognition, bioimaging, and targeted anticancer drug delivery.

  8. Noncanonical self-assembly of multifunctional DNA nanoflowers for biomedical applications

    PubMed Central

    Zhu, Guizhi; Hu, Rong; Zhao, Zilong; Chen, Zhuo; Zhang, Xiaobing; Tan, Weihong

    2013-01-01

    DNA nanotechnology has been extensively explored to assemble various functional nanostructures for versatile applications. Mediated by Watson-Crick base-pairing, these DNA nanostructures have been conventionally assembled through hybridization of many short DNA building blocks. Here we report the noncanonical self-assembly of multifunctional DNA nanostructures, termed as nanoflowers (NFs), and the versatile biomedical applications. These NFs were assembled from long DNA building blocks generated via Rolling Circle Replication (RCR) of a designer template. NF assembly was driven by liquid crystallization and dense packaging of building blocks, without relying on Watson-Crick base-pairing between DNA strands, thereby avoiding the otherwise conventional complicated DNA sequence design. NF sizes were readily tunable in a wide range, by simply adjusting such parameters as assembly time and template sequences. NFs were exceptionally resistant to nuclease degradation, denaturation, or dissociation at extremely low concentration, presumably resulting from the dense DNA packaging in NFs. The exceptional biostability is critical for biomedical applications. By rational design, NFs can be readily incorporated with myriad functional moieties. All these properties make NFs promising for versatile applications. As a proof-of-principle demonstration, in this study, NFs were integrated with aptamers, bioimaging agents, and drug loading sites, and the resultant multifunctional NFs were demonstrated for selective cancer cell recognition, bioimaging, and targeted anticancer drug delivery. PMID:24164620

  9. Modular Self-Assembly of Protein Cage Lattices for Multistep Catalysis

    DOE PAGES

    Uchida, Masaki; McCoy, Kimberly; Fukuto, Masafumi; ...

    2017-11-13

    The assembly of individual molecules into hierarchical structures is a promising strategy for developing three-dimensional materials with properties arising from interaction between the individual building blocks. Virus capsids are elegant examples of biomolecular nanostructures, which are themselves hierarchically assembled from a limited number of protein subunits. Here, we demonstrate the bio-inspired modular construction of materials with two levels of hierarchy: the formation of catalytically active individual virus-like particles (VLPs) through directed self-assembly of capsid subunits with enzyme encapsulation, and the assembly of these VLP building blocks into three-dimensional arrays. The structure of the assembled arrays was successfully altered from anmore » amorphous aggregate to an ordered structure, with a face-centered cubic lattice, by modifying the exterior surface of the VLP without changing its overall morphology, to modulate interparticle interactions. The assembly behavior and resultant lattice structure was a consequence of interparticle interaction between exterior surfaces of individual particles and thus independent of the enzyme cargos encapsulated within the VLPs. These superlattice materials, composed of two populations of enzyme-packaged VLP modules, retained the coupled catalytic activity in a two-step reaction for isobutanol synthesis. As a result, this study demonstrates a significant step toward the bottom-up fabrication of functional superlattice materials using a self-assembly process across multiple length scales and exhibits properties and function that arise from the interaction between individual building blocks.« less

  10. Modular Self-Assembly of Protein Cage Lattices for Multistep Catalysis

    PubMed Central

    Uchida, Masaki; McCoy, Kimberly; Fukuto, Masafumi; Yang, Lin; Yoshimura, Hideyuki; Miettinen, Heini M.; LaFrance, Ben; Patterson, Dustin P.; Schwarz, Benjamin; Karty, Jonathan A.; Prevelige, Peter E.; Lee, Byeongdu; Douglas, Trevor

    2018-01-01

    The assembly of individual molecules into hierarchical structures is a promising strategy for developing three-dimensional materials with properties arising from interaction between the individual building blocks. Virus capsids are elegant examples of biomolecular nanostructures, which are themselves hierarchically assembled from a limited number of protein subunits. Here we demonstrate the bio-inspired modular construction of materials with two levels of hierarchy; the formation of catalytically active individual virus-like particles (VLPs) through directed self-assembly of capsid subunits with enzyme encapsulation, and the assembly of these VLP building blocks into three-dimensional arrays. The structure of the assembled arrays was successfully altered from an amorphous aggregate to an ordered structure, with a face-centered cubic lattice, by modifying the exterior surface of the VLP without changing its overall morphology, to modulate interparticle interactions. The assembly behavior and resultant lattice structure was a consequence of interparticle interaction between exterior surfaces of individual particles, and thus independent of the enzyme cargos encapsulated within the VLPs. These superlattice materials, composed of two populations of enzyme packaged VLP modules, retained the coupled catalytic activity in a two-step reaction for isobutanol synthesis. This study demonstrates a significant step toward the bottom-up fabrication of functional superlattice materials using a self-assembly process across multiple length scales, and exhibits properties and function that arise from the interaction between individual building blocks. PMID:29131580

  11. Modular Self-Assembly of Protein Cage Lattices for Multistep Catalysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Uchida, Masaki; McCoy, Kimberly; Fukuto, Masafumi

    The assembly of individual molecules into hierarchical structures is a promising strategy for developing three-dimensional materials with properties arising from interaction between the individual building blocks. Virus capsids are elegant examples of biomolecular nanostructures, which are themselves hierarchically assembled from a limited number of protein subunits. Here, we demonstrate the bio-inspired modular construction of materials with two levels of hierarchy: the formation of catalytically active individual virus-like particles (VLPs) through directed self-assembly of capsid subunits with enzyme encapsulation, and the assembly of these VLP building blocks into three-dimensional arrays. The structure of the assembled arrays was successfully altered from anmore » amorphous aggregate to an ordered structure, with a face-centered cubic lattice, by modifying the exterior surface of the VLP without changing its overall morphology, to modulate interparticle interactions. The assembly behavior and resultant lattice structure was a consequence of interparticle interaction between exterior surfaces of individual particles and thus independent of the enzyme cargos encapsulated within the VLPs. These superlattice materials, composed of two populations of enzyme-packaged VLP modules, retained the coupled catalytic activity in a two-step reaction for isobutanol synthesis. As a result, this study demonstrates a significant step toward the bottom-up fabrication of functional superlattice materials using a self-assembly process across multiple length scales and exhibits properties and function that arise from the interaction between individual building blocks.« less

  12. The continuous assembly and transfer of nanoelements

    NASA Astrophysics Data System (ADS)

    Kumar, Arun

    Patterned nanoelements on flexible polymeric substrates at micro/nano scale at high rate, low cost, and commercially viable route offer an opportunity for manufacturing devices with micro/nano scale features. These micro/nano scale now made with various nanoelement can enhance the device functionality in sensing and switching due to their improved conductivity and better mechanical properties. In this research the fundamental understanding of high rate assembly and transfer of nanoelements has been developed. To achieve this objective, three sub topics were made. In the first step, the use of electrophoresis for the controlled assembly of CNT's on interdigitated templates has been shown. The time scale of assembly reported is shorter than the previously reported assembly time (60 seconds). The mass deposited was also predicted using the Hamaker's law. It is also shown that pre-patterned CNT's could be transferred from the rigid templates onto flexible polymeric substrates using a thermoforming process. The time scale of transfer is less than one minute (50 seconds) and was found to be dependent on polymer chemistry. It was found that CNT's preferentially transfer from Au electrode to non-polar polymeric substrates (polyurethane and polyethylene terephalathate glycol) in the thermoforming process. In the second step, a novel process (Pulsed Electrophoresis) has been shown for the first time to assist the assembly of conducting polyaniline on gold nanowire interdigitated templates. This technique offers dynamic control over heat build-up, which has been a main drawback in the DC electrophoresis and AC dielectrophoresis as well as the main cause of nanowire template damage. The use of this technique allowed higher voltages to be applied, resulting in shorter assembly times (e.g., 17.4 seconds, assembly resolution of 100 nm). The pre-patterned templates with PANi deposition were subsequently used to transfer the nanoscale assembled PANi from the rigid templates to thermoplastic polyurethane using the thermoforming process. In the third step, a novel integration of high rate pulsed electrophoretic assembly with thermally assisted transfer in a roll-to-roll process has been shown. This technique allowed the whole assembly and transfer process to take place in only 30 seconds. Further, a processing window is developed to control the percent area coverage of PANi with the aid of the belt speed. Also shown is the effect of different types of polymer on the quality of transfer, and it concluded that the transfer is affected by the polymer chemistry.

  13. Multiscale assembly for tissue engineering and regenerative medicine

    PubMed Central

    Inci, Fatih; Tasoglu, Savas; Erkmen, Burcu; Demirci, Utkan

    2015-01-01

    Our understanding of cell biology and its integration with materials science has led to technological innovations in the bioengineering of tissue-mimicking grafts that can be utilized in clinical and pharmaceutical applications. Bio-engineering of native-like multiscale building blocks provides refined control over the cellular microenvironment, thus enabling functional tissues. In this review, we focus on assembling building blocks from the biomolecular level to the millimeter scale. We also provide an overview of techniques for assembling molecules, cells, spheroids, and microgels and achieving bottom-up tissue engineering. Additionally, we discuss driving mechanisms for self- and guided assembly to create micro-to-macro scale tissue structures. PMID:25796488

  14. Emerging Technologies for Assembly of Microscale Hydrogels

    PubMed Central

    Kavaz, Doga; Demirel, Melik C.; Demirci, Utkan

    2013-01-01

    Assembly of cell encapsulating building blocks (i.e., microscale hydrogels) has significant applications in areas including regenerative medicine, tissue engineering, and cell-based in vitro assays for pharmaceutical research and drug discovery. Inspired by the repeating functional units observed in native tissues and biological systems (e.g., the lobule in liver, the nephron in kidney), assembly technologies aim to generate complex tissue structures by organizing microscale building blocks. Novel assembly technologies enable fabrication of engineered tissue constructs with controlled properties including tunable microarchitectural and predefined compositional features. Recent advances in micro- and nano-scale technologies have enabled engineering of microgel based three dimensional (3D) constructs. There is a need for high-throughput and scalable methods to assemble microscale units with a complex 3D micro-architecture. Emerging assembly methods include novel technologies based on microfluidics, acoustic and magnetic fields, nanotextured surfaces, and surface tension. In this review, we survey emerging microscale hydrogel assembly methods offering rapid, scalable microgel assembly in 3D, and provide future perspectives and discuss potential applications. PMID:23184717

  15. Assembly and Commissioning of Naval Postgraduate School Gas Gun for Impact Studies

    DTIC Science & Technology

    2009-12-01

    MAIN GAS GUN ASSEMBLY............................................................ 12 1. Launcher Mount Assembly...12 Figure 8. Launcher Mount Assembly [After 5].................................................... 13 Figure 9. Breech...5] The main gas gun assembly comprises of eight sub-assemblies. The assemblies are mounted onto the launcher mount assembly, where it acts as a

  16. Sandia National Laboratories, Tonopah Test Range Assembly Building 9B (Building 09-54): Photographs and Written Historical and Descriptive Data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ullrich, Rebecca A.

    Assembly Building 9B (Building 09-54) is a contributing element to the Sandia National Laboratories (SNL) Tonopah Test Range (TTR) Historic District. The SNL TTR Historic District played a significant role in U.S. Cold War history in the areas of stockpile surveillance and non-nuclear field testing of nuclear weapons designs. The district covers approximately 179,200 acres and illustrates Cold War development testing of nuclear weapons components and systems. This report includes historical information, architectural information, sources of information, project information, maps, blueprints, and photographs.

  17. 75 FR 12710 - Airworthiness Directives; Bombardier, Inc., Model DHC-8-400 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-17

    ... for the main landing gear lock actuator assembly, retraction actuator assembly rod end and piston, and... for the main landing gear lock actuator assembly, retraction actuator assembly rod end and piston, and..., retraction actuator assembly rod end and piston, and the upper bearing in the main landing gear shock strut...

  18. KSC-02pd0591

    NASA Image and Video Library

    2002-04-29

    KENNEDY SPACE CENTER, FLA. -- Space Shuttle Endeavour rests on Launch Pad 39A after rollout from the Vehicle Assembly Building. The Shuttle comprises the orbiter, in front, and the taller orange external tank behind it flanked by twin solid rocket boosters. On either side of Endeavour's tail and main engines are the tail service masts that support the fluid,, gas and electrical requirements of the orbiter's liquid oxyen and liquid hydrogen aft T-0 umbilicals. Mission STS-111 is designated UF-2, the 14th assembly flight to the International Space Station. Endeavour's payload includes the Multi-Purpose Logistics Module Leonardo and Mobile Base System. The mission also will swap resident crews on the Station, carrying the Expedition 5 crew and returning to Earth Expedition 4. Liftoff of Endeavour is scheduled between 4 and 8 p.m. May 30, 2002

  19. Credit BG. The north and west sides of this structure ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit BG. The north and west sides of this structure appear as seen when looking east (88°). Building E-67, the tunnel entrance, gives personnel access to the tunnel system. The Assembly Building served as a shop for test crews; it contained a small lathe and other tools for making specialized parts. No explosives were allowed in this structure. Air conditioning ducts are on the roof - Jet Propulsion Laboratory Edwards Facility, Assembly Building, Edwards Air Force Base, Boron, Kern County, CA

  20. Total synthesis of TMG-chitotriomycin based on an automated electrochemical assembly of a disaccharide building block

    PubMed Central

    Isoda, Yuta; Sasaki, Norihiko; Kitamura, Kei; Takahashi, Shuji; Manmode, Sujit; Takeda-Okuda, Naoko; Tamura, Jun-ichi

    2017-01-01

    The total synthesis of TMG-chitotriomycin using an automated electrochemical synthesizer for the assembly of carbohydrate building blocks is demonstrated. We have successfully prepared a precursor of TMG-chitotriomycin, which is a structurally-pure tetrasaccharide with typical protecting groups, through the methodology of automated electrochemical solution-phase synthesis developed by us. The synthesis of structurally well-defined TMG-chitotriomycin has been accomplished in 10-steps from a disaccharide building block. PMID:28684973

  1. 5. ROOF DETAIL, LOOKING EAST TOWARD SECOND FLOOR WAREHOUSE FROM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. ROOF DETAIL, LOOKING EAST TOWARD SECOND FLOOR WAREHOUSE FROM ROOF OF ASSEMBLY AREA. - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  2. WEAPONS STORAGE AREA. FROM RIGHT TO LEFT, ABOVEGROUND STORAGE MAGAZINE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    WEAPONS STORAGE AREA. FROM RIGHT TO LEFT, ABOVEGROUND STORAGE MAGAZINE (BUILDING 3568), SPARES INERT STORAGE BUILDING (BUILDING 3570), MISSILE ASSEMBLY SHOP (BUILDING 3578) AND SEGREGATED MAGAZINE STORAGE BUILDING (BUILDING 3572). VIEW TO NORTHWEST - Plattsburgh Air Force Base, U.S. Route 9, Plattsburgh, Clinton County, NY

  3. Analysis on the cost structure of product recall for reverse supply chain

    NASA Astrophysics Data System (ADS)

    Yanhua, Feng; Xuhui, Xia; Zheng, Yang

    2017-12-01

    The research on the reverse supply chain of product recall mainly focused on the recall network structure, logistics mode and so on. In this paper, when product recall and supply channel are fixed, the specific structure and function expression of cost are analyzed according to the peak season and off-season of recall activities, and whether the assembly manufacturer, supplier and recyclers are cooperated situation, respectively, to build the total cost structure of the function model. Finally, the model is validated correctly through the automotive industry and the electromechanical industry.

  4. KSC-98pc1067

    NASA Image and Video Library

    1998-09-14

    In the Vehicle Assembly Building, the orbiter Discovery (viewed from behind the Space Shuttle Main Engines) is raised to a vertical position in order to be mated with the external tank. The orbiter displays the recently painted NASA logo, termed the "meatball," on its left, or port, wing. The logo also has been painted on both sides of the aft fuselage. Discovery (OV-103), the first of the orbiters to be launched with the new art work, is scheduled for its 25th flight, from Launch Pad 39B, on Oct. 29, 1998, for the STS-95 mission

  5. KSC-98pc1068

    NASA Image and Video Library

    1998-09-14

    In the Vehicle Assembly Building, the orbiter Discovery (viewed from below the Space Shuttle Main Engines, starboard side) is raised to a vertical position in order to be mated with the external tank. The orbiter displays the recently painted NASA logo, termed the "meatball," on the aft fuselage. The logo also has been painted on the left, or port, wing. Discovery (OV-103), the first of the orbiters to be launched with the new art work, is scheduled for its 25th flight, from Launch Pad 39B, on Oct. 29, 1998, for the STS-95 mission

  6. Norm Abram of 'This Old House' visits KSC to film for show

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Members of the crew of the television series This Old House get a close look at one of the main engines on Space Shuttle Atlantis in the Vehicle Assembly Building. At left is Norm Abram, master carpenter on the series. Next to him is Steve Thomas, host of the show. At the far right is astronaut John Herrington, who is accompanying the film crew on their tour of KSC. The cast and crew of This Old House are filming at KSC for an episode of the show.

  7. Building bridges between cellular and molecular structural biology.

    PubMed

    Patwardhan, Ardan; Brandt, Robert; Butcher, Sarah J; Collinson, Lucy; Gault, David; Grünewald, Kay; Hecksel, Corey; Huiskonen, Juha T; Iudin, Andrii; Jones, Martin L; Korir, Paul K; Koster, Abraham J; Lagerstedt, Ingvar; Lawson, Catherine L; Mastronarde, David; McCormick, Matthew; Parkinson, Helen; Rosenthal, Peter B; Saalfeld, Stephan; Saibil, Helen R; Sarntivijai, Sirarat; Solanes Valero, Irene; Subramaniam, Sriram; Swedlow, Jason R; Tudose, Ilinca; Winn, Martyn; Kleywegt, Gerard J

    2017-07-06

    The integration of cellular and molecular structural data is key to understanding the function of macromolecular assemblies and complexes in their in vivo context. Here we report on the outcomes of a workshop that discussed how to integrate structural data from a range of public archives. The workshop identified two main priorities: the development of tools and file formats to support segmentation (that is, the decomposition of a three-dimensional volume into regions that can be associated with defined objects), and the development of tools to support the annotation of biological structures.

  8. LPT. Low power assembly and test building (TAN640). Camera facing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    LPT. Low power assembly and test building (TAN-640). Camera facing west. Rollup doors to each test cell face east. Concrete walls poured in place. Apparatus at right of view was part of a post-ANP program. INEEL negative no. HD-40-1-1 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

  9. PBF Reactor Building (PER620). Detail of fuel test assembly in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PBF Reactor Building (PER-620). Detail of fuel test assembly in preparation for test. When complete, it will fit into in-pile tube. The maximum outside diameter of which must be about 8.25 inches. Date: 1982. INEEL negative no. 82-4908 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

  10. KSC-05pd2349

    NASA Image and Video Library

    2005-10-25

    KENNEDY SPACE CENTER, FLA. - A piece of metal lies on the ground near the NASA Kennedy Space Center’s Vehicle Assembly Building following the wrath of hurricane Wilma as it crossed the state Oct. 24. Kennedy’s facilities sustained minor structural damage, primarily to roofs or from water intrusion. The Vehicle Assembly Building lost some panels on the east and west sides. Some facilities lost power. A total of 13.6 inches of rain was recorded at the Shuttle Landing Facility. The highest wind gust recorded was 94 mph from the north-northwest at Launch Pad 39B, while the maximum sustained wind was 76 mph from the north-northwest at the top of the 492-foot weather tower located north of the Vehicle Assembly Building.

  11. KSC-05pd2352

    NASA Image and Video Library

    2005-10-25

    KENNEDY SPACE CENTER, FLA. - Pieces of metal lie alongside a fence near NASA Kennedy Space Center’s Vehicle Assembly Building following the wrath of hurricane Wilma as it crossed the state Oct. 24. Kennedy’s facilities sustained minor structural damage, primarily to roofs or from water intrusion. The Vehicle Assembly Building lost some panels on the east and west sides. Some facilities lost power. A total of 13.6 inches of rain was recorded at the Shuttle Landing Facility. The highest wind gust recorded was 94 mph from the north-northwest at Launch Pad 39B, while the maximum sustained wind was 76 mph from the north-northwest at the top of the 492-foot weather tower located north of the Vehicle Assembly Building.

  12. Recommendations for Safe Separation Distances from the Kennedy Space Center (KSC) Vehicle Assembly Building (VAB) Using a Heat-Flux-Based Analytical Approach (Abridged)

    NASA Technical Reports Server (NTRS)

    Cragg, Clinton H.; Bowman, Howard; Wilson, John E.

    2011-01-01

    The NASA Engineering and Safety Center (NESC) was requested to provide computational modeling to support the establishment of a safe separation distance surrounding the Kennedy Space Center (KSC) Vehicle Assembly Building (VAB). The two major objectives of the study were 1) establish a methodology based on thermal flux to determine safe separation distances from the Kennedy Space Center's (KSC's) Vehicle Assembly Building (VAB) with large numbers of solid propellant boosters containing hazard division 1.3 classification propellants, in case of inadvertent ignition; and 2) apply this methodology to the consideration of housing eight 5-segment solid propellant boosters in the VAB. The results of the study are contained in this report.

  13. Silesia Dryvit

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Presz, K.

    1995-12-31

    MT International, as a manufacturer and distributor for of US company named Dryvit Systems is focused on weatherization techniques as well as on facade and external wall finishing. The materials manufactured by Dryvit for building and construction purposes (plaster masses, building binders, insulating materials, reinforced fabric, etc.) are used at many sites. The consistent and well-selected composition of these materials guarantees highest quality of facade finishing in building structures of any type. The first implementation of Dryvit system in Warsaw was completed in 1974 and it remains the first exampled of professionally weatherized building in Poland. Different versions of Dryvitmore » system have been elaborated for various plaster base types. Consequently the assembling procedure differs, too. The main classification includes methods used directly on-site by a specialized contractor as well as prefabrication systems in which the ready-made elements prefabricated in a central plant or in a moveable unit are mounted on the walls. Distribution of materials and systems is based upon a network of branch offices and plaster mass mixter plants located in Warsaw, Szczecin, Lublin, Gdansk and Zabrze.« less

  14. Practical identification of moisture sources in building assemblies using infrared thermography

    NASA Astrophysics Data System (ADS)

    McIntosh, Gregory B.; Colantonio, Antonio

    2015-05-01

    Water, in its various phases, in any environment other than desert (hot or cold) conditions, is the single most destructive element that causes deterioration of materials and failure of building assemblies. It is the key element present in the formation of mold and fungi that lead to indoor air quality problems. Water is the primary element that needs to be managed in buildings to ensure human comfort, health and safety. Under the right thermodynamic conditions the detection of moisture in its various states is possible through the use of infrared thermography for a large variety of building assemblies and materials. The difficulty is that moisture is transient and mobile from one environment to another via air movement, vapor pressure or phase change. Building materials and enclosures provide both repositories and barriers to this moisture movement. In real life steady state conditions do not exist for moisture within building materials and enclosures. Thus the detection of moisture is in a constant state of transition. Sometimes you will see it and sometimes you will not. Understanding the limitations at the time of inspection will go a long way to mitigating unsatisfied clients or difficult litigation. Moisture detection can be observed by IRT via three physical mechanisms; latent heat absorption or release during phase change; a change in conductive heat transfer; and a change in thermal capacitance. Complicating the three methodologies is the factor of variable temperature differentials and variable mass air flow on, through and around surfaces being inspected. Building enclosures come in variable assembly types and are designed to perform differently in different environmental regions. Sources for moisture accumulation will vary for different environmental conditions. Detection methodologies will change for each assembly type in different ambient environments. This paper will look at the issue of the methodologies for detection of the presence of moisture and determination of the various sources from which it accumulates in building assemblies. The end objective for IRT based moisture detection inspections is not to just identify that moisture is present but to determine its extent and source. Accurate assessment of the source(s) and root cause of the moisture is critical to the development of a permanent solution to the problem.

  15. 6. PERSPECTIVE VIEW TO SOUTHWEST SHOWING NORTHWEST CORNER OF ASSEMBLY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. PERSPECTIVE VIEW TO SOUTHWEST SHOWING NORTHWEST CORNER OF ASSEMBLY BUILDING WHERE SHOWROOMS (FIRST FLOOR) AND OFFICES (SECOND FLOOR) WERE LOCATED. WEST SIDE OF ASSEMBLY AREA IS TO RIGHT. - Rosie the Riveter National Historical Park, Ford Assembly Plant, 1400 Harbour Way South, Richmond, Contra Costa County, CA

  16. Single Day Construction of Multigene Circuits with 3G Assembly.

    PubMed

    Halleran, Andrew D; Swaminathan, Anandh; Murray, Richard M

    2018-05-18

    The ability to rapidly design, build, and test prototypes is of key importance to every engineering discipline. DNA assembly often serves as a rate limiting step of the prototyping cycle for synthetic biology. Recently developed DNA assembly methods such as isothermal assembly and type IIS restriction enzyme systems take different approaches to accelerate DNA construction. We introduce a hybrid method, Golden Gate-Gibson (3G), that takes advantage of modular part libraries introduced by type IIS restriction enzyme systems and isothermal assembly's ability to build large DNA constructs in single pot reactions. Our method is highly efficient and rapid, facilitating construction of entire multigene circuits in a single day. Additionally, 3G allows generation of variant libraries enabling efficient screening of different possible circuit constructions. We characterize the efficiency and accuracy of 3G assembly for various construct sizes, and demonstrate 3G by characterizing variants of an inducible cell-lysis circuit.

  17. Space Shuttle Projects

    NASA Image and Video Library

    1983-07-01

    This photograph was taken during the final assembly phase of the Space Shuttle light weight external tanks (LWT) 5, 6, and 7 at the Michoud Assembly Facility in New Orleans, Louisiana. The giant cylinder, higher than a 15-story building, with a length of 154-feet (47-meters) and a diameter of 27.5-feet (8.4-meters), is the largest single piece of the Space Shuttle. During launch, the external tank (ET) acts as a backbone for the orbiter and solid rocket boosters. In separate, internal pressurized tank sections, the ET holds the liquid hydrogen fuel and liquid oxygen oxidizer for the Shuttle's three main engines. During launch, the ET feeds the fuel under pressure through 17-inch (43.2-centimeter) ducts which branch off into smaller lines that feed directly into the main engines. Some 64,000 gallons (242,260 liters) of fuel are consumed by the main engines each minute. Machined from aluminum alloys, the Space Shuttle's ET is the only part of the launch vehicle that currently is not reused. After its 526,000 gallons (1,991,071 liters) of propellants are consumed during the first 8.5 minutes of flight, it is jettisoned from the orbiter and breaks up in the upper atmosphere, its pieces falling into remote ocean waters. The Marshall Space Flight Center was responsible for developing the ET

  18. Colloidal polymers with controlled sequence and branching constructed from magnetic field assembled nanoparticles.

    PubMed

    Bannwarth, Markus B; Utech, Stefanie; Ebert, Sandro; Weitz, David A; Crespy, Daniel; Landfester, Katharina

    2015-03-24

    The assembly of nanoparticles into polymer-like architectures is challenging and usually requires highly defined colloidal building blocks. Here, we show that the broad size-distribution of a simple dispersion of magnetic nanocolloids can be exploited to obtain various polymer-like architectures. The particles are assembled under an external magnetic field and permanently linked by thermal sintering. The remarkable variety of polymer-analogue architectures that arises from this simple process ranges from statistical and block copolymer-like sequencing to branched chains and networks. This library of architectures can be realized by controlling the sequencing of the particles and the junction points via a size-dependent self-assembly of the single building blocks.

  19. Building 932, oblique view to northwest, 90 mm lens. Building ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Building 932, oblique view to northwest, 90 mm lens. Building 933-935 at extreme left. - Travis Air Force Base, Nuclear Weapons Assembly Plant 5, W Street, Armed Forces Special Weapons Project Q Area, Fairfield, Solano County, CA

  20. Invited Article: Autonomous assembly of atomically perfect nanostructures using a scanning tunneling microscope

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Celotta, Robert J., E-mail: robert.celotta@nist.gov, E-mail: joseph.stroscio@nist.gov; Hess, Frank M.; Rutter, Gregory M.

    2014-12-15

    A major goal of nanotechnology is to develop the capability to arrange matter at will by placing individual atoms at desired locations in a predetermined configuration to build a nanostructure with specific properties or function. The scanning tunneling microscope has demonstrated the ability to arrange the basic building blocks of matter, single atoms, in two-dimensional configurations. An array of various nanostructures has been assembled, which display the quantum mechanics of quantum confined geometries. The level of human interaction needed to physically locate the atom and bring it to the desired location limits this atom assembly technology. Here we report themore » use of autonomous atom assembly via path planning technology; this allows atomically perfect nanostructures to be assembled without the need for human intervention, resulting in precise constructions in shorter times. We demonstrate autonomous assembly by assembling various quantum confinement geometries using atoms and molecules and describe the benefits of this approach.« less

  1. Inverse Problem in Self-assembly

    NASA Astrophysics Data System (ADS)

    Tkachenko, Alexei

    2012-02-01

    By decorating colloids and nanoparticles with DNA, one can introduce highly selective key-lock interactions between them. This leads to a new class of systems and problems in soft condensed matter physics. In particular, this opens a possibility to solve inverse problem in self-assembly: how to build an arbitrary desired structure with the bottom-up approach? I will present a theoretical and computational analysis of the hierarchical strategy in attacking this problem. It involves self-assembly of particular building blocks (``octopus particles''), that in turn would assemble into the target structure. On a conceptual level, our approach combines elements of three different brands of programmable self assembly: DNA nanotechnology, nanoparticle-DNA assemblies and patchy colloids. I will discuss the general design principles, theoretical and practical limitations of this approach, and illustrate them with our simulation results. Our crucial result is that not only it is possible to design a system that has a given nanostructure as a ground state, but one can also program and optimize the kinetic pathway for its self-assembly.

  2. LPT. Shield test facility assembly and test building (TAN646), south ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    LPT. Shield test facility assembly and test building (TAN-646), south end of EBOR helium wing. Camera facing north. Monorail protrudes from upper-level door. Rust marks on concrete wall are from stack. Metal shed is post-1970 addition. INEEL negative no. HD-40-8-1 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

  3. Expert Meeting Report. Interior Insulation Retrofit of Mass Masonry Wall Assemblies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ueno, K.; Van Straaten, R.

    2012-02-01

    The Building Science Consortium held an Expert Meeting on Interior Insulation Retrofit of Mass Masonry Wall Assemblies on July 30, 2011, at the Westford Regency Hotel in Westford, MA. This report outlines the extensive information that was presented on assessment of risk factors for premature building deterioration due to interior insulation retrofits, and methods to reduce such risks.

  4. Expert Meeting Report: Interior Insulation Retrofit of Mass Masonry Wall Assemblies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ueno, K.; Van Straaten, R.

    2012-02-01

    The Building Science Consortium held an Expert Meeting on Interior Insulation Retrofit of Mass Masonry Wall Assemblies on July 30, 2011 at the Westford Regency Hotel in Westford, MA. This report outlines the extensive information that was presented on assessment of risk factors for premature building deterioration due to interior insulation retrofits, and methods to reduce such risks.

  5. Photocopy of drawing. LAUNCH COMPLEX 39. NASA John F. Kennedy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of drawing. LAUNCH COMPLEX 39. NASA John F. Kennedy Space Center, Florida. File Number 203-100, Urbahn-Roberts-Seelye-Moran, October 1963. VERTICAL ASSEMBLY BUILDING, LOW BAY, SECTIONS J-J, K-K, & L-L. Sheet 33-32 - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  6. Vice President Mike Pence Speech at Vehicle Assembly Building

    NASA Image and Video Library

    2017-07-06

    Vice President Mike Pence got a first-hand look at the public-private partnerships at America’s multi-user spaceport on Thursday, July 6, during a visit to NASA’s Kennedy Space Center in Florida. Speaking in the center’s iconic Vehicle Assembly Building, the Vice President thanked employees for their commitment to America’s continued leadership in the space frontier.

  7. KENNEDY SPACE CENTER, FLA. - Smoke from a successful controlled burn near KSC’s Launch Complex 39 surrounds the Vehicle Assembly Building and spreads across the horizon. The water in the foreground is the Banana River.

    NASA Image and Video Library

    2003-11-24

    KENNEDY SPACE CENTER, FLA. - Smoke from a successful controlled burn near KSC’s Launch Complex 39 surrounds the Vehicle Assembly Building and spreads across the horizon. The water in the foreground is the Banana River.

  8. 126. JOB NO. X98396, PLANT LAYOUT, FORD MOTOR COMPANY LONG ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    126. JOB NO. X9-8396, PLANT LAYOUT, FORD MOTOR COMPANY LONG BEACH ASSEMBLY PLANT, MARCH 1940. - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  9. A triaxial supramolecular weave

    NASA Astrophysics Data System (ADS)

    Lewandowska, Urszula; Zajaczkowski, Wojciech; Corra, Stefano; Tanabe, Junki; Borrmann, Ruediger; Benetti, Edmondo M.; Stappert, Sebastian; Watanabe, Kohei; Ochs, Nellie A. K.; Schaeublin, Robin; Li, Chen; Yashima, Eiji; Pisula, Wojciech; Müllen, Klaus; Wennemers, Helma

    2017-11-01

    Despite recent advances in the synthesis of increasingly complex topologies at the molecular level, nano- and microscopic weaves have remained difficult to achieve. Only a few diaxial molecular weaves exist—these were achieved by templation with metals. Here, we present an extended triaxial supramolecular weave that consists of self-assembled organic threads. Each thread is formed by the self-assembly of a building block comprising a rigid oligoproline segment with two perylene-monoimide chromophores spaced at 18 Å. Upon π stacking of the chromophores, threads form that feature alternating up- and down-facing voids at regular distances. These voids accommodate incoming building blocks and establish crossing points through CH-π interactions on further assembly of the threads into a triaxial woven superstructure. The resulting micrometre-scale supramolecular weave proved to be more robust than non-woven self-assemblies of the same building block. The uniform hexagonal pores of the interwoven network were able to host iridium nanoparticles, which may be of interest for practical applications.

  10. Fuel-Mediated Transient Clustering of Colloidal Building Blocks.

    PubMed

    van Ravensteijn, Bas G P; Hendriksen, Wouter E; Eelkema, Rienk; van Esch, Jan H; Kegel, Willem K

    2017-07-26

    Fuel-driven assembly operates under the continuous influx of energy and results in superstructures that exist out of equilibrium. Such dissipative processes provide a route toward structures and transient behavior unreachable by conventional equilibrium self-assembly. Although perfected in biological systems like microtubules, this class of assembly is only sparsely used in synthetic or colloidal analogues. Here, we present a novel colloidal system that shows transient clustering driven by a chemical fuel. Addition of fuel causes an increase in hydrophobicity of the building blocks by actively removing surface charges, thereby driving their aggregation. Depletion of fuel causes reappearance of the charged moieties and leads to disassembly of the formed clusters. This reassures that the system returns to its initial, equilibrium state. By taking advantage of the cyclic nature of our system, we show that clustering can be induced several times by simple injection of new fuel. The fuel-mediated assembly of colloidal building blocks presented here opens new avenues to the complex landscape of nonequilibrium colloidal structures, guided by biological design principles.

  11. 50. Neg. No. F176B, Jun 5, 1936, EXTERIORFORD ASSEMBLY PLANT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    50. Neg. No. F-176B, Jun 5, 1936, EXTERIOR-FORD ASSEMBLY PLANT AT LONG BEACH, OVERALL VIEW OF PLANT FROM THE HENRY FORD BRIDGE, CERRITOS CHANNEL IN THE FOREGROUND - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  12. Precise Truss Assembly Using Commodity Parts and Low Precision Welding

    NASA Technical Reports Server (NTRS)

    Komendera, Erik; Reishus, Dustin; Dorsey, John T.; Doggett, W. R.; Correll, Nikolaus

    2014-01-01

    Hardware and software design and system integration for an intelligent precision jigging robot (IPJR), which allows high precision assembly using commodity parts and low-precision bonding, is described. Preliminary 2D experiments that are motivated by the problem of assembling space telescope optical benches and very large manipulators on orbit using inexpensive, stock hardware and low-precision welding are also described. An IPJR is a robot that acts as the precise "jigging", holding parts of a local structure assembly site in place, while an external low precision assembly agent cuts and welds members. The prototype presented in this paper allows an assembly agent (for this prototype, a human using only low precision tools), to assemble a 2D truss made of wooden dowels to a precision on the order of millimeters over a span on the order of meters. The analysis of the assembly error and the results of building a square structure and a ring structure are discussed. Options for future work, to extend the IPJR paradigm to building in 3D structures at micron precision are also summarized.

  13. Cyclodextrins as versatile building blocks for regenerative medicine.

    PubMed

    Alvarez-Lorenzo, Carmen; García-González, Carlos A; Concheiro, Angel

    2017-12-28

    Cyclodextrins (CDs) are one of the most versatile substances produced by nature, and it is in the aqueous biological environment where the multifaceted potential of CDs can be completely unveiled. CDs form inclusion complexes with a variety of guest molecules, including polymers, producing very diverse biocompatible supramolecular structures. Additionally, CDs themselves can trigger cell differentiation to distinct lineages depending on the substituent groups and also promote salt nucleation. These features together with the affinity-driven regulated release of therapeutic molecules, growth factors and gene vectors explain the rising interest for CDs as building blocks in regenerative medicine. Supramolecular poly(pseudo)rotaxane structures and zipper-like assemblies exhibit outstanding viscoelastic properties, performing as syringeable implants. The sharp shear-responsiveness of the supramolecular assemblies is opening new avenues for the design of bioinks for 3D printing and also of electrospun fibers. CDs can also be transformed into polymerizable monomers to prepare alternative nanostructured materials. The aim of this review is to analyze the role that CDs may play in regenerative medicine through the analysis of the last decade research. Most applications of CD-based scaffolds are focussed on non-healing bone fractures, cartilage reparation and skin recovery, but also on even more challenging demands such as neural grafts. For the sake of clarity, main sections of this review are organized according to the architecture of the CD-based scaffolds, mainly syringeable supramolecular hydrogels, 3D printed scaffolds, electrospun fibers, and composites, since the same scaffold type may find application in different tissues. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. 114. JOB NO. 1347K, SHEET 1M, 1929, FORD MOTOR COMPANY; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    114. JOB NO. 1347-K, SHEET 1M, 1929, FORD MOTOR COMPANY; BOILER HOUSE ASSEMBLY PLANT; PLAN - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  15. 113. JOB NO. 1347K, SHEET 2M, 1929, FORD MOTOR COMPANY; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    113. JOB NO. 1347-K, SHEET 2M, 1929, FORD MOTOR COMPANY; BOILER HOUSE ASSEMBLY PLANT; SECTIONS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  16. 14. VIEW TO WESTSOUTHWEST ACROSS CAR TEST TRACT SITE TO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. VIEW TO WEST-SOUTHWEST ACROSS CAR TEST TRACT SITE TO NORTH END OF ASSEMBLY PLANT, SHOWING NORTH END ADDITIONS. - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  17. Assembly Modulated by Particle Position and Shape: A New Concept in Self-Assembly.

    PubMed

    Tavacoli, Joe W; Heuvingh, Julien; Du Roure, Olivia

    2017-11-10

    In this communication we outline how the bespoke arrangements and design of micron-sized superparamagnetic shapes provide levers to modulate their assembly under homogeneous magnetic fields. We label this new approach, 'assembly modulated by particle position and shape' (APPS). Specifically, using rectangular lattices of superparamagnetic micron-sized cuboids, we construct distinct microstructures by adjusting lattice pitch and angle of array with respect to a magnetic field. Broadly, we find two modes of assembly: (1) immediate 2D jamming of the cuboids as they rotate to align with the applied field (rotation-induced jamming) and (2) aggregation via translation after their full alignment (dipole-dipole assembly). The boundary between these two assembly pathways is independent on field strength being solely a function of the cuboid's dimensions, lattice pitch, and array angle with respect to field-a relationship which we capture, along with other features of the assembly process, in a 'phase diagram'. In doing so, we set out initial design rules to build custom made assemblies. Moreover, these assemblies can be made flexible thanks to the hinged contacts of their particle building blocks. This flexibility, combined with the superparamagnetic nature of the architectures, renders our assembly method particularly appropriate for the construction of complex actuators at a scale hitherto not possible.

  18. KENNEDY SPACE CENTER, FLA. - In the Vehicle Assembly Building, Jim Landy, NDE specialist, performs flash thermography on flight crew lockers. He is screening the lockers for hidden damage underneath dings and dents that might occur during handling.

    NASA Image and Video Library

    2003-09-04

    KENNEDY SPACE CENTER, FLA. - In the Vehicle Assembly Building, Jim Landy, NDE specialist, performs flash thermography on flight crew lockers. He is screening the lockers for hidden damage underneath dings and dents that might occur during handling.

  19. KENNEDY SPACE CENTER, FLA. - In the Vehicle Assembly Building, Jim Landy, NDE specialist, examines flight crew lockers using flash thermography. He is screening the lockers for hidden damage underneath dings and dents that might occur during handling.

    NASA Image and Video Library

    2003-09-04

    KENNEDY SPACE CENTER, FLA. - In the Vehicle Assembly Building, Jim Landy, NDE specialist, examines flight crew lockers using flash thermography. He is screening the lockers for hidden damage underneath dings and dents that might occur during handling.

  20. ETR COMPRESSOR BUILDING, TRA643. CAMERA FACES NORTHEAST. WATER HEAT EXCHANGER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ETR COMPRESSOR BUILDING, TRA-643. CAMERA FACES NORTHEAST. WATER HEAT EXCHANGER IS IN LEFT FOREGROUND. A PARTIALLY ASSEMBLED PLANT AIR CONDITIONER IS AT CENTER. WORKERS AT RIGHT ASSEMBLE 4000 HORSEPOWER COMPRESSOR DRIVE MOTOR AT RIGHT. INL NEGATIVE NO. 56-3714. R.G. Larsen, Photographer, 11/13/1956 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  1. CRAWLER HIDDEN UNDER MOBILE LAUNCHER MOVES APOLLO 17 FROM VEHICLE ASSEMBLY BUILDING AS TRIP TO LAUNC

    NASA Technical Reports Server (NTRS)

    1972-01-01

    The Apollo 17 space vehicle was moved today from the Vehicle Assembly Building to Complex 39's pad A in preparation for its launch with Astronauts Eugene A. Cernan, Commander; Ronald A. Evans, Command Module Pilot; and Dr. Harrison H. ''Jack'' Schmitt, Lunar Module Pilot, on the sixth U.S. manned lunar landing mission on December 6, 1972.

  2. General view of the Solid Rocket Booster's (SRB) Solid Rocket ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of the Solid Rocket Booster's (SRB) Solid Rocket Motor Segments in the Surge Building of the Rotation Processing and Surge Facility at Kennedy Space Center awaiting transfer to the Vehicle Assembly Building and subsequent mounting and assembly on the Mobile Launch Platform. - Space Transportation System, Solid Rocket Boosters, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  3. Advanced Sensors for TBI

    DTIC Science & Technology

    2016-12-01

    SMD-VAC- GP, Virtual Industries) with plastic tip. Then the chip was covered with silicone open-cell foam (0.062” thick, HT -870, Stockwell...the build. 26 We discussed with a sub- contractor in Livermore who might be able to perform the packaging assembly work. Dr. Kotovsky...worked with the sub- contractor on practice assemblies anticipating the new upcoming build. Working through an outside contractor represents an enormous

  4. Research on construction quality and improvement of assembly construction

    NASA Astrophysics Data System (ADS)

    Cheng, Fei

    2017-11-01

    Based on the acceleration of the urbanization process and the improvement of the quality of life of our residents, the demand for building construction has been increasing. In this context, the construction industry in order to promote the construction efficiency, quality improvement, to meet the needs of the development of the times to strengthen the new technology, the use of new technologies. At present, China’s engineering construction units in the process of carrying out the project to strengthen the use of assembly-type construction technology, which thus achieved for the traditional construction work low-level, high time-consuming issues, and promote the steady improvement of production efficiency. Based on this, this paper focuses on the analysis of the connotation of the assembly structure and analyzes the quality problems in the construction process of the construction projects and puts forward the improvement measures to promote the improvement of the building quality and the construction of the building Construction speed. Based on this, this paper analyzes the structural system and design of prefabricated building.

  5. Colloidosome like structures: self-assembly of silica microrods

    DOE PAGES

    Datskos, P.; Polizos, G.; Bhandari, M.; ...

    2016-03-07

    Self-assembly of one-dimensional structures is attracting a great deal of interest because assembled structures can provide better properties compared to individual building blocks. We demonstrate silica microrod self-assembly by exploiting Pickering emulsion based strategy. Micron-sized silica rods were synthesized employing previously reported methods based on polyvinylpyrrolidone/ pentanol emulsion droplets. Moreover, rods self-assembled to make structures in the range of z10 40 mm. Smooth rods assembled better than segmented rods. Finally, the assembled structures were bonded by weak van der Waals forces.

  6. Nanoscale superstructures assembled by polymerase chain reaction (PCR): programmable construction, structural diversity, and emerging applications.

    PubMed

    Kuang, Hua; Ma, Wei; Xu, Liguang; Wang, Libing; Xu, Chuanlai

    2013-11-19

    Polymerase chain reaction (PCR) is an essential tool in biotechnology laboratories and is becoming increasingly important in other areas of research. Extensive data obtained over the last 12 years has shown that the combination of PCR with nanoscale dispersions can resolve issues in the preparation DNA-based materials that include both inorganic and organic nanoscale components. Unlike conventional DNA hybridization and antibody-antigen complexes, PCR provides a new, effective assembly platform that both increases the yield of DNA-based nanomaterials and allows researchers to program and control assembly with predesigned parameters including those assisted and automated by computers. As a result, this method allows researchers to optimize to the combinatorial selection of the DNA strands for their nanoparticle conjugates. We have developed a PCR approach for producing various nanoscale assemblies including organic motifs such as small molecules, macromolecules, and inorganic building blocks, such as nanorods (NRs), metal, semiconductor, and magnetic nanoparticles (NPs). We start with a nanoscale primer and then modify that building block using the automated steps of PCR-based assembly including initialization, denaturation, annealing, extension, final elongation, and final hold. The intermediate steps of denaturation, annealing, and extension are cyclic, and we use computer control so that the assembled superstructures reach their predetermined complexity. The structures assembled using a small number of PCR cycles show a lower polydispersity than similar discrete structures obtained by direct hybridization between the nanoscale building blocks. Using different building blocks, we assembled the following structural motifs by PCR: (1) discrete nanostructures (NP dimers, NP multimers including trimers, pyramids, tetramers or hexamers, etc.), (2) branched NP superstructures and heterochains, (3) NP satellite-like superstructures, (4) Y-shaped nanostructures and DNA networks, (5) protein-DNA co-assembly structures, and (6) DNA block copolymers including trimers and pentamers. These results affirm that this method can produce a variety of chemical structures and in yields that are tunable. Using PCR-based preparation of DNA-bridged nanostructures, we can program the assembly of the nanoscale blocks through the adjustment of the primer intensity on the assembled units, the number of PCR cycles, or both. The resulting structures are highly complex and diverse and have interesting dynamics and collective properties. Potential applications of these materials include chirooptical materials, probe fabrication, and environmental and biomedical sensors.

  7. 115. JOB NO. 1347K, SHEET 3M, 1929/1930, FORD MOTOR COMPANY; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    115. JOB NO. 1347-K, SHEET 3M, 1929/1930, FORD MOTOR COMPANY; BOILER HOUSE ASSEMBLY PLANT; BOILER SETTING - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  8. An active locking mechanism for assembling 3D micro structures

    NASA Astrophysics Data System (ADS)

    Zhang, Ping; Mayyas, Mohammad; Lee, Woo Ho; Popa, Dan; Shiakolas, Panos; Stephanou, Harry; Chiao, J. C.

    2007-01-01

    Microassembly is an enabling technology to build 3D microsystems consisting of microparts made of different materials and processes. Multiple microparts can be connected together to construct complicated in-plane and out-of-plane microsystems by using compliant mechanical structures such as micro hinges and snap fasteners. This paper presents design, fabrication, and assembly of an active locking mechanism that provides mechanical and electrical interconnections between mating microparts. The active locking mechanism is composed of thermally actuated Chevron beams and sockets. Assembly by means of an active locking mechanism offers more flexibility in designing microgrippers as it reduces or minimizes mating force, which is one of the main reasons causing fractures in a microgripper during microassembly operation. Microgrippers, microparts, and active locking mechanisms were fabricated on a silicon substrate using the deep reactive ion etching (DRIE) processes with 100-um thick silicon on insulator (SOI) wafers. A precision robotic assembly platform with a dual microscope vision system was used to automate the manipulation and assembly processes of microparts. The assembly sequence includes (1) tether breaking and picking up of a micropart by using an electrothermally actuated microgripper, (2) opening of a socket area for zero-force insertion, (3) a series of translation and rotation of a mating micropart to align it onto the socket, (4) insertion of a micropart into the socket, and (5) deactivation and releasing of locking fingers. As a result, the micropart was held vertically to the substrate and locked by the compliance of Chevron beams. Microparts were successfully assembled using the active locking mechanism and the measured normal angle was 89.2°. This active locking mechanism provides mechanical and electrical interconnections, and it can potentially be used to implement a reconfigurable microrobot that requires complex assembly of multiple links and joints.

  9. Measure Guideline: Water Management at Tub and Shower Assemblies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dickson, B.

    2011-12-01

    Due to the high concentrations of water and the consequential risk of water damage to the home's structure a comprehensive water management system is imperative to protect the building assemblies underlying the finish surround of tub and shower areas. This guide shows how to install fundamental waterproofing strategies to prevent water related issues at shower and tub areas. When conducting a total gut rehab of a structure or constructing a new home, best practice installation and detailing for effective waterproofing are critically important at bathtub and shower assemblies. Water management issues in a structure may go unrecognized for long periods,more » so that when they are finally observed, the damage from long-term water exposure is extensive. A gut rehab is often undertaken when a home has experienced a natural disaster or when the homeowners are interested in converting an old, high-energy-use building into a high-quality, efficient structure that meets or exceeds one of the national energy standards, such as ENERGY STAR or LEED for homes. During a gut rehab, bath areas need to be replaced with diligent attention to detail. Employing effective water management practices in the installation and detailing of tub and shower assemblies will minimize or eliminate water issues within the building cavities and on the finished surfaces. A residential tub-and-shower surround or shower-stall assembly is designed to handle a high volume of water - 2.5 gallons per minute, with multiple baths occurring during a typical day. Transitions between dissimilar materials and connections between multiple planes must be installed with care to avoid creating a pathway for water to enter the building assemblies. Due to the high volume of water and the consequential risk of water damage to the home's structure, a comprehensive water management system is imperative to protect the building assemblies underlying the finish surround of tub and shower areas. At each stage of construction, successive trades must take care not to create a defect nor to compound or cover up a previous trade's defect. Covering a defect hides the inevitable point of failure and may even exacerbate the situation.« less

  10. 20. INTERIOR OF BUILDING 1606. VIEW TO SOUTH. Rocky ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. INTERIOR OF BUILDING 1606. VIEW TO SOUTH. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  11. 19. INTERIOR OF BUILDING 1606. VIEW TO SOUTH. Rocky ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. INTERIOR OF BUILDING 1606. VIEW TO SOUTH. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  12. 22. INTERIOR OF BUILDING 1606. VIEW TO NORTH. Rocky ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. INTERIOR OF BUILDING 1606. VIEW TO NORTH. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  13. 11. INTERIOR OF BUILDING 1606. VIEW TO WEST. Rocky ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. INTERIOR OF BUILDING 1606. VIEW TO WEST. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  14. 18. INTERIOR OF BUILDING 1606. VIEW TO SOUTH. Rocky ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. INTERIOR OF BUILDING 1606. VIEW TO SOUTH. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  15. 13. INTERIOR OF BUILDING 1606. VIEW TO WEST. Rocky ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. INTERIOR OF BUILDING 1606. VIEW TO WEST. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  16. 10. INTERIOR OF BUILDING 1606. VIEW TO SOUTH. Rocky ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. INTERIOR OF BUILDING 1606. VIEW TO SOUTH. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  17. 8. INTERIOR OF BUILDING 1601. VIEW TO NORTH. Rocky ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. INTERIOR OF BUILDING 1601. VIEW TO NORTH. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  18. 6. INTERIOR OF BUILDING 1601. VIEW TO SOUTHEAST. Rocky ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. INTERIOR OF BUILDING 1601. VIEW TO SOUTHEAST. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  19. 9. INTERIOR OF BUILDING 1601. VIEW TO SOUTH. Rocky ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. INTERIOR OF BUILDING 1601. VIEW TO SOUTH. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  20. 23. INTERIOR OF BUILDING 1607. VIEW TO NORTH. Rocky ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. INTERIOR OF BUILDING 1607. VIEW TO NORTH. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  1. 7. INTERIOR OF BUILDING 1601. VIEW TO SOUTH. Rocky ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. INTERIOR OF BUILDING 1601. VIEW TO SOUTH. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  2. Large-scale self-assembly of uniform submicron silver sulfide material driven by precise pressure control

    NASA Astrophysics Data System (ADS)

    Qi, Juanjuan; Chen, Ke; Zhang, Shuhao; Yang, Yun; Guo, Lin; Yang, Shihe

    2017-03-01

    The controllable self-assembly of nanosized building blocks into larger specific structures can provide an efficient method of synthesizing novel materials with excellent properties. The self-assembly of nanocrystals by assisted means is becoming an extremely active area of research, because it provides a method of producing large-scale advanced functional materials with potential applications in the areas of energy, electronics, optics, and biologics. In this study, we applied an efficient strategy, namely, the use of ‘pressure control’ to the assembly of silver sulfide (Ag2S) nanospheres with a diameter of approximately 33 nm into large-scale, uniform Ag2S sub-microspheres with a size of about 0.33 μm. More importantly, this strategy realizes the online control of the overall reaction system, including the pressure, reaction time, and temperature, and could also be used to easily fabricate other functional materials on an industrial scale. Moreover, the thermodynamics and kinetics parameters for the thermal decomposition of silver diethyldithiocarbamate (Ag(DDTC)) are also investigated to explore the formation mechanism of the Ag2S nanosized building blocks which can be assembled into uniform sub-micron scale architecture. As a method of producing sub-micron Ag2S particles by means of the pressure-controlled self-assembly of nanoparticles, we foresee this strategy being an efficient and universally applicable option for constructing other new building blocks and assembling novel and large functional micromaterials on an industrial scale.

  3. General view of a fully assembled Solid Rocket Booster sitting ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of a fully assembled Solid Rocket Booster sitting atop the Mobile Launch Platform in the Vehicle Assembly Building at Kennedy Space Center - Space Transportation System, Solid Rocket Boosters, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  4. Layer-by-layer assembly of two-dimensional materials into wafer-scale heterostructures

    NASA Astrophysics Data System (ADS)

    Kang, Kibum; Lee, Kan-Heng; Han, Yimo; Gao, Hui; Xie, Saien; Muller, David A.; Park, Jiwoong

    2017-10-01

    High-performance semiconductor films with vertical compositions that are designed to atomic-scale precision provide the foundation for modern integrated circuitry and novel materials discovery. One approach to realizing such films is sequential layer-by-layer assembly, whereby atomically thin two-dimensional building blocks are vertically stacked, and held together by van der Waals interactions. With this approach, graphene and transition-metal dichalcogenides--which represent one- and three-atom-thick two-dimensional building blocks, respectively--have been used to realize previously inaccessible heterostructures with interesting physical properties. However, no large-scale assembly method exists at present that maintains the intrinsic properties of these two-dimensional building blocks while producing pristine interlayer interfaces, thus limiting the layer-by-layer assembly method to small-scale proof-of-concept demonstrations. Here we report the generation of wafer-scale semiconductor films with a very high level of spatial uniformity and pristine interfaces. The vertical composition and properties of these films are designed at the atomic scale using layer-by-layer assembly of two-dimensional building blocks under vacuum. We fabricate several large-scale, high-quality heterostructure films and devices, including superlattice films with vertical compositions designed layer-by-layer, batch-fabricated tunnel device arrays with resistances that can be tuned over four orders of magnitude, band-engineered heterostructure tunnel diodes, and millimetre-scale ultrathin membranes and windows. The stacked films are detachable, suspendable and compatible with water or plastic surfaces, which will enable their integration with advanced optical and mechanical systems.

  5. Layer-by-layer assembly of two-dimensional materials into wafer-scale heterostructures.

    PubMed

    Kang, Kibum; Lee, Kan-Heng; Han, Yimo; Gao, Hui; Xie, Saien; Muller, David A; Park, Jiwoong

    2017-10-12

    High-performance semiconductor films with vertical compositions that are designed to atomic-scale precision provide the foundation for modern integrated circuitry and novel materials discovery. One approach to realizing such films is sequential layer-by-layer assembly, whereby atomically thin two-dimensional building blocks are vertically stacked, and held together by van der Waals interactions. With this approach, graphene and transition-metal dichalcogenides-which represent one- and three-atom-thick two-dimensional building blocks, respectively-have been used to realize previously inaccessible heterostructures with interesting physical properties. However, no large-scale assembly method exists at present that maintains the intrinsic properties of these two-dimensional building blocks while producing pristine interlayer interfaces, thus limiting the layer-by-layer assembly method to small-scale proof-of-concept demonstrations. Here we report the generation of wafer-scale semiconductor films with a very high level of spatial uniformity and pristine interfaces. The vertical composition and properties of these films are designed at the atomic scale using layer-by-layer assembly of two-dimensional building blocks under vacuum. We fabricate several large-scale, high-quality heterostructure films and devices, including superlattice films with vertical compositions designed layer-by-layer, batch-fabricated tunnel device arrays with resistances that can be tuned over four orders of magnitude, band-engineered heterostructure tunnel diodes, and millimetre-scale ultrathin membranes and windows. The stacked films are detachable, suspendable and compatible with water or plastic surfaces, which will enable their integration with advanced optical and mechanical systems.

  6. Lock and Key Colloids through Polymerization-Induced Buckling of Monodispersed Silicon Oil Droplets

    NASA Astrophysics Data System (ADS)

    Sacanna, Stefano; Irvine, William T. M.; Chaikin, Paul M.; Pine, David J.

    2010-03-01

    Colloidal particles can spontaneously associate into larger structured aggregates when driven by selective and directional interactions. Colloidal organization can be programmed by engineering shapes and interactions of basic building blocks in a manner similar to molecular self-assembly. Examples of successful strategies that allow non-trivial assembly of particles include template-directed patterning, capillary forces and, most commonly, the functionalization of the particle surfaces with ``sticky patches'' of biological or synthetic molecules. The level of complexity of the realizable assemblies, increases when particles with well defined shape anisotropies are used. In particular depletion forces and specific surface treatments in combination with non spherical particles have proven to be powerful tools to self-assembly complex microstructures. We describe a simple, high yield, synthetic pathway to fabricate monodisperse hybrid silica spheres with well defined cavities. Because the particle morphologies are reproducible and tunable with precision, the resulting particles can be used as basic building blocks in the assembly of larger monodisperse clusters. This is demonstrated using depletion to drive the self-assembly.

  7. Layer-by-layer assembled biopolymer microcapsule with separate layer cavities generated by gas-liquid microfluidic approach.

    PubMed

    Wang, Yifeng; Zhou, Jing; Guo, Xuecheng; Hu, Qian; Qin, Chaoran; Liu, Hui; Dong, Meng; Chen, Yanjun

    2017-12-01

    In this work, a layer-by-layer (LbL) assembled biopolymer microcapsule with separate layer cavities is generated by a novel and convenient gas-liquid microfluidic approach. This approach exhibits combined advantages of microfluidic approach and LbL assembly method, and it can straightforwardly build LbL-assembled capsules in mild aqueous environments at room temperature. In particular, using this approach we can build the polyelectrolyte multilayer capsule with favorable cavities in each layer, and without the need for organic solvent, emulsifying agent, or sacrificial template. Various components (e.g., drugs, proteins, fluorescent dyes, and nanoparticles) can be respectively encapsulated in the separate layer cavities of the LbL-assembled capsules. Moreover, the encapsulated capsules present the ability as colorimetric sensors, and they also exhibit the interesting release behavior. Therefore, the LbL-assembled biopolymer capsule is a promising candidate for biomedical applications in targeted delivery, controlled release, and bio-detection. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Mesoscale Graphene-like Honeycomb Mono- and Multilayers Constructed via Self-Assembly of Coclusters.

    PubMed

    Hou, Xue-Sen; Zhu, Guo-Long; Ren, Li-Jun; Huang, Zi-Han; Zhang, Rui-Bin; Ungar, Goran; Yan, Li-Tang; Wang, Wei

    2018-02-07

    Honeycomb structure endows graphene with extraordinary properties. But could a honeycomb monolayer superlattice also be generated via self-assembly of colloids or nanoparticles? Here we report the construction of mono- and multilayer molecular films with honeycomb structure that can be regarded as self-assembled artificial graphene (SAAG). We construct fan-shaped molecular building blocks by covalently connecting two kinds of clusters, one polyoxometalate and four polyhedral oligomeric silsesquioxanes. The precise shape control enables these complex molecules to self-assemble into a monolayer 2D honeycomb superlattice that mirrors that of graphene but on the mesoscale. The self-assembly of the SAAG was also reproduced via coarse-grained molecular simulations of a fan-shaped building block. It revealed a hierarchical process and the key role of intermediate states in determining the honeycomb structure. Experimental images also show a diversity of bi- and trilayer stacking modes. The successful creation of SAAG and its stacks opens up prospects for the preparation of novel self-assembled nanomaterials with unique properties.

  9. Self-assembling peptide-based building blocks in medical applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Acar, Handan; Srivastava, Samanvaya; Chung, Eun Ji

    Peptides and peptide-conjugates, comprising natural and synthetic building blocks, are an increasingly popular class of biomaterials. Self-assembled nanostructures based on peptides and peptide-conjugates offer advantages such as precise selectivity and multifunctionality that can address challenges and limitations in the clinic. In this review article, we discuss recent developments in the design and self-assembly of various nanomaterials based on peptides and peptide-conjugates for medical applications, and categorize them into two themes based on the driving forces of molecular self-assembly. First, we present the self-assembled nanostructures driven by the supramolecular interactions between the peptides, with or without the presence of conjugates. Themore » studies where nanoassembly is driven by the interactions between the conjugates of peptide-conjugates are then presented. Particular emphasis is given to in vivo studies focusing on therapeutics, diagnostics, immune modulation and regenerative medicine. Finally, challenges and future perspectives are presented.« less

  10. Natural supramolecular building blocks: from virus coat proteins to viral nanoparticles.

    PubMed

    Liu, Zhi; Qiao, Jing; Niu, Zhongwei; Wang, Qian

    2012-09-21

    Viruses belong to a fascinating class of natural supramolecular structures, composed of multiple copies of coat proteins (CPs) that assemble into different shapes with a variety of sizes from tens to hundreds of nanometres. Because of their advantages including simple/economic production, well-defined structural features, unique shapes and sizes, genetic programmability and robust chemistries, recently viruses and virus-like nanoparticles (VLPs) have been used widely in biomedical applications and materials synthesis. In this critical review, we highlight recent advances in the use of virus coat proteins (VCPs) and viral nanoparticles (VNPs) as building blocks in self-assembly studies and materials development. We first discuss the self-assembly of VCPs into VLPs, which can efficiently incorporate a variety of different materials as cores inside the viral protein shells. Then, the self-assembly of VNPs at surfaces or interfaces is summarized. Finally, we discuss the co-assembly of VNPs with different functional materials (178 references).

  11. KSC-99pp0198

    NASA Image and Video Library

    1999-02-09

    KENNEDY SPACE CENTER, FLA. -- In the transfer aisle of the Vehicle Assembly Building, Atlantis awaits a vacancy in one of the Orbiter Processing Facility bays. Seen behind the left wing is an external tank being raised to a vertical position. The largest and heaviest element of the Space Shuttle, an external tank contains the liquid hydrogen fuel and liquid oxygen oxidizer for the three Space Shuttle main engines (SSMEs) in the orbiter during liftoff and ascent. When the SSMEs are shut down, the external tank is jettisoned, breaking up as it enters the Earth's atmopshere and impacting in a remote ocean area. It is not recovered

  12. KSC-99pp0197

    NASA Image and Video Library

    1999-02-09

    KENNEDY SPACE CENTER, FLA. -- In the transfer aisle of the Vehicle Assembly Building, Atlantis awaits a vacancy in one of the Orbiter Processing Facility bays. Seen behind the right wing is an external tank being raised to a vertical position. The largest and heaviest element of the Space Shuttle, an external tank contains the liquid hydrogen fuel and liquid oxygen oxidizer for the three Space Shuttle main engines (SSMEs) in the orbiter during liftoff and ascent. When the SSMEs are shut down, the external tank is jettisoned, breaking up as it enters the Earth's atmopshere and impacting in a remote ocean area. It is not recovered

  13. STS-95 Discovery undergoes vertical lift in the VAB

    NASA Technical Reports Server (NTRS)

    1998-01-01

    In the Vehicle Assembly Building, the orbiter Discovery (viewed from behind the Space Shuttle Main Engines) is raised to a vertical position in order to be mated with the external tank. The orbiter displays the recently painted NASA logo, termed the 'meatball,' on its left, or port, wing. The logo also has been painted on both sides of the aft fuselage. Discovery (OV-103), the first of the orbiters to be launched with the new art work, is scheduled for its 25th flight, from Launch Pad 39B, on Oct. 29, 1998, for the STS-95 mission.

  14. STS-95 Discovery undergoes vertical lift in the VAB

    NASA Technical Reports Server (NTRS)

    1998-01-01

    In the Vehicle Assembly Building, the orbiter Discovery (viewed from behind the Space Shuttle Main Engines, port side) is raised to a vertical position in order to be mated with the external tank. The orbiter displays the recently painted NASA logo, termed the 'meatball,' on its left, or port, wing. The logo also has been painted on both sides of the aft fuselage. Discovery (OV- 103), the first of the orbiters to be launched with the new art work, is scheduled for its 25th flight, from Launch Pad 39B, on Oct. 29, 1998, for the STS-95 mission.

  15. STS-95 Discovery undergoes vertical lift in the VAB

    NASA Technical Reports Server (NTRS)

    1998-01-01

    In the Vehicle Assembly Building, the orbiter Discovery (viewed from below the Space Shuttle Main Engines, starboard side) is raised to a vertical position in order to be mated with the external tank. The orbiter displays the recently painted NASA logo, termed the 'meatball,' on the aft fuselage. The logo also has been painted on the left, or port, wing. Discovery (OV-103), the first of the orbiters to be launched with the new art work, is scheduled for its 25th flight, from Launch Pad 39B, on Oct. 29, 1998, for the STS-95 mission.

  16. KSC-98pc1066

    NASA Image and Video Library

    1998-09-14

    In the Vehicle Assembly Building, the orbiter Discovery (viewed from behind the Space Shuttle Main Engines, port side) is raised to a vertical position in order to be mated with the external tank. The orbiter displays the recently painted NASA logo, termed the "meatball," on its left, or port, wing. The logo also has been painted on both sides of the aft fuselage. Discovery (OV-103), the first of the orbiters to be launched with the new art work, is scheduled for its 25th flight, from Launch Pad 39B, on Oct. 29, 1998, for the STS-95 mission

  17. KENNEDY SPACE CENTER, FLA. - The external tank in the Vehicle Assembly Building (VAB) is destacked from the solid rocket boosters. The tank and SRBs were configured for Atlantis and mission STS-114. The tank will remain in the VAB.

    NASA Image and Video Library

    2003-05-20

    KENNEDY SPACE CENTER, FLA. - The external tank in the Vehicle Assembly Building (VAB) is destacked from the solid rocket boosters. The tank and SRBs were configured for Atlantis and mission STS-114. The tank will remain in the VAB.

  18. KENNEDY SPACE CENTER, FLA. - An area of the Vehicle Assembly Building is being prepared to store the debris collected from Space Shuttle Columbia. About 83,000 pieces were shipped to KSC during search and recovery efforts in East Texas.

    NASA Image and Video Library

    2003-09-02

    KENNEDY SPACE CENTER, FLA. - An area of the Vehicle Assembly Building is being prepared to store the debris collected from Space Shuttle Columbia. About 83,000 pieces were shipped to KSC during search and recovery efforts in East Texas.

  19. LPT. Shield test facility assembly and test building (TAN646). East ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    LPT. Shield test facility assembly and test building (TAN-646). East facade of ebor helium wing addition. Camera facing west. Note asbestos-cement siding on stair enclosure and upper-level. Concrete siding at lower level. Metal stack. Monorail protrudes from upper level of south wall at left of view. INEEL negative no. HD-40-7-4 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

  20. KENNEDY SPACE CENTER, FLA. - In the Vehicle Assembly Building, Jim Landy, NDE specialist, sets up a flight crew lockers for flash thermography. He is screening the lockers for hidden damage underneath dings and dents that might occur during handling.

    NASA Image and Video Library

    2003-09-04

    KENNEDY SPACE CENTER, FLA. - In the Vehicle Assembly Building, Jim Landy, NDE specialist, sets up a flight crew lockers for flash thermography. He is screening the lockers for hidden damage underneath dings and dents that might occur during handling.

  1. Detail, rear door types, building 242, oblique view to southwest, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail, rear door types, building 242, oblique view to southwest, 90 mm lens. - Travis Air Force Base, Nuclear Weapons Assembly Building, W Street, Armed Forces Special Weapons Project Q Area, Fairfield, Solano County, CA

  2. NanoShuttles: Harnessing Motor Proteins to Transport Cargo in Synthetic Environments

    NASA Astrophysics Data System (ADS)

    Vogel, V.; Hess, H.

    Motors have become a crucial commodity in our daily lives, from transportation to driving conveyor belts that enable the sequential assembly of cars and other industrial machines. For the sequential assembly of building blocks at the nanoscale that would not assemble spontaneously into larger functional systems, however, active transport systems are not yet available. In contrast, cells have evolved sophisticated molecular machinery that drives movement and active transport. Driven by the conversion of chemical into mechanical energy, namely through hydrolysis of the biological fuel ATP, molecular motors enable cells to operate far away from equilibrium by transporting organelles and molecules to designated locations within the cell, often against concentration gradients. Inspired by the biological concept of active transport, major efforts are underway to learn how to build nanoscale transport systems that are driven by molecular motors. Emerging engineering principles are discussed of how to build tracks and junctions to guide such nanoshuttles, how to load them with cargo and control their speed, how to use active transport to assemble mesoscopic structures that would otherwise not assemble spontaneously and what polymeric materials to choose to integrate motors into MEMS and other biohybrid devices. Finally, two applications that exploit the physical properties of microtubules are discussed, surface imaging by a swarm of microtubules and a self-assembled picoNewton force meter to probe receptor-ligand interactions.

  3. KSC-04PD-2561

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. In a Vehicle Assembly Building (VAB) high bay, workers monitor the movement of a Solid Rocket Booster (SRB) aft center segment as it is lowered toward an aft segment already secured to a Mobile Launch Platform. These segments are part of the right SRB for the Space Shuttle Return to Flight mission, STS-114. Two SRBs are stacked on a Mobile Launch Platform for each Shuttle flight and later joined by an External Tank. The twin 149-foot tall, 12-foot diameter SRBs provide the main propulsion system during launch. They operate in parallel with the Space Shuttle main engines for the first two minutes of flight and jettison away from the orbiter with help from the Booster Separation Motors, about 26.3 nautical miles above the Earths surface.

  4. KSC-04PD-2562

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. In a Vehicle Assembly Building (VAB) high bay, workers check the alignment of a Solid Rocket Booster (SRB) aft center segment as it is lowered toward an aft segment already secured to a Mobile Launch Platform. These segments are part of the right SRB for the Space Shuttle Return to Flight mission, STS-114. Two SRBs are stacked on a Mobile Launch Platform for each Shuttle flight and later joined by an External Tank. The twin 149-foot tall, 12-foot diameter SRBs provide the main propulsion system during launch. They operate in parallel with the Space Shuttle main engines for the first two minutes of flight and jettison away from the orbiter with help from the Booster Separation Motors, about 26.3 nautical miles above the Earths surface.

  5. KSC-04PD-2565

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. In a Vehicle Assembly Building (VAB) high bay, workers check the alignment of a Solid Rocket Booster (SRB) aft center segment which has been lowered onto an aft segment already secured to a Mobile Launch Platform. These segments are part of the right SRB for the Space Shuttle Return to Flight mission, STS-114. Two SRBs are stacked on a Mobile Launch Platform for each Shuttle flight and later joined by an External Tank. The twin 149-foot tall, 12-foot diameter SRBs provide the main propulsion system during launch. They operate in parallel with the Space Shuttle main engines for the first two minutes of flight and jettison away from the orbiter with help from the Booster Separation Motors, about 26.3 nautical miles above the Earths surface.

  6. A parametric study of the thermal performance of green roofs in different climates through energy modeling

    NASA Astrophysics Data System (ADS)

    Mukherjee, Sananda

    In recent years, there has been great interest in the potential of green roofs as an alternative roofing option to reduce the energy consumed by individual buildings as well as mitigate large scale urban environmental problems such as the heat island effect. There is a widespread recognition and a growing literature of measured data that suggest green roofs can reduce building energy consumption. This thesis investigates the potential of green roofs in reducing the building energy loads and focuses on how the different parameters of a green roof assembly affect the thermal performance of a building. A green roof assembly is modeled in Design Builder- a 3D graphical design modeling and energy use simulation program (interface) that uses the EnergyPlus simulation engine, and the simulated data set thus obtained is compared to field experiment data to validate the roof assembly model on the basis of how accurately it simulates the behavior of a green roof. Then the software is used to evaluate the thermal performance of several green roof assemblies under three different climate types, looking at the whole building energy consumption. For the purpose of this parametric simulation study, a prototypical single story small office building is considered and one parameter of the green roof is altered for each simulation run in order to understand its effect on building's energy loads. These parameters include different insulation thicknesses, leaf area indices (LAI) and growing medium or soil depth, each of which are tested under the three different climate types. The energy use intensities (EUIs), the peak and annual heating and cooling loads resulting from the use of these green roof assemblies are compared with each other and to a cool roof base case to determine the energy load reductions, if any. The heat flux through the roof is also evaluated and compared. The simulation results are then organized and finally presented as a decision support tool that would facilitate the adoption and appropriate utilization of green roof technologies and make it possible to account for green roof benefits in energy codes and related energy efficiency standards and rating systems such as LEED.

  7. The SSMEPF opens with a ribbon-cutting ceremony

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Participants in the ribbon cutting for KSC's new 34,600-square- foot Space Shuttle Main Engine Processing Facility (SSMEPF) pose in front of a Space Shuttle Main Engine on display for the ceremony. From left, they are Ed Adamek, vice president and associate program manager for Ground Operations of United Space Alliance; John Plowden, vice president of Rocketdyne; Donald R. McMonagle, manager of Launch Integration; U.S. Congressman Dave Weldon; KSC Center Director Roy D. Bridges Jr.; Wade Ivey of Ivey Construction, Inc.; and Robert B. Sieck, director of Shuttle Processing. A major addition to the existing Orbiter Processing Facility Bay 3, the SSMEPF replaces the Shuttle Main Engine Shop located in the Vehicle Assembly Building (VAB). The decision to move the shop out of the VAB was prompted by safety considerations and recent engine processing improvements. The first three main engines to be processed in the new facility will fly on Shuttle Endeavour's STS-88 mission in December 1998.

  8. Mobius Assembly: A versatile Golden-Gate framework towards universal DNA assembly.

    PubMed

    Andreou, Andreas I; Nakayama, Naomi

    2018-01-01

    Synthetic biology builds upon the foundation of engineering principles, prompting innovation and improvement in biotechnology via a design-build-test-learn cycle. A community-wide standard in DNA assembly would enable bio-molecular engineering at the levels of predictivity and universality in design and construction that are comparable to other engineering fields. Golden Gate Assembly technology, with its robust capability to unidirectionally assemble numerous DNA fragments in a one-tube reaction, has the potential to deliver a universal standard framework for DNA assembly. While current Golden Gate Assembly frameworks (e.g. MoClo and Golden Braid) render either high cloning capacity or vector toolkit simplicity, the technology can be made more versatile-simple, streamlined, and cost/labor-efficient, without compromising capacity. Here we report the development of a new Golden Gate Assembly framework named Mobius Assembly, which combines vector toolkit simplicity with high cloning capacity. It is based on a two-level, hierarchical approach and utilizes a low-frequency cutter to reduce domestication requirements. Mobius Assembly embraces the standard overhang designs designated by MoClo, Golden Braid, and Phytobricks and is largely compatible with already available Golden Gate part libraries. In addition, dropout cassettes encoding chromogenic proteins were implemented for cost-free visible cloning screening that color-code different cloning levels. As proofs of concept, we have successfully assembled up to 16 transcriptional units of various pigmentation genes in both operon and multigene arrangements. Taken together, Mobius Assembly delivers enhanced versatility and efficiency in DNA assembly, facilitating improved standardization and automation.

  9. Building 933935, oblique view to southeast showing, left to right, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Building 933-935, oblique view to southeast showing, left to right, rear doors to building 933, 934, 935, 90 mm lens. Building 933 is in foreground. - Travis Air Force Base, Nuclear Weapons Assembly Plant 4, W Street, Armed Forces Special Weapons Project Q Area, Fairfield, Solano County, CA

  10. Hierarchical Materials Design by Pattern Transfer Printing of Self-Assembled Binary Nanocrystal Superlattices

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Paik, Taejong; Yun, Hongseok; Fleury, Blaise

    We demonstrate the fabrication of hierarchical materials by controlling the structure of highly ordered binary nanocrystal superlattices (BNSLs) on multiple length scales. Combinations of magnetic, plasmonic, semiconducting, and insulating colloidal nanocrystal (NC) building blocks are self-assembled into BNSL membranes via the liquid–interfacial assembly technique. Free-standing BNSL membranes are transferred onto topographically structured poly(dimethylsiloxane) molds via the Langmuir–Schaefer technique and then deposited in patterns onto substrates via transfer printing. BNSLs with different structural motifs are successfully patterned into various meso- and microstructures such as lines, circles, and even three-dimensional grids across large-area substrates. A combination of electron microscopy and grazing incidencemore » small-angle X-ray scattering (GISAXS) measurements confirm the ordering of NC building blocks in meso- and micropatterned BNSLs. This technique demonstrates structural diversity in the design of hierarchical materials by assembling BNSLs from NC building blocks of different composition and size by patterning BNSLs into various size and shape superstructures of interest for a broad range of applications.« less

  11. 26. BOMBS IN CRATE IN BUILDING 1607. VIEW TO NORTHWEST. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. BOMBS IN CRATE IN BUILDING 1607. VIEW TO NORTHWEST. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  12. Layer-by-Layer Enabled Nanomaterials for Chemical Sensing and Energy Conversion

    NASA Astrophysics Data System (ADS)

    Paterno, Leonardo G.; Soler, Maria A. G.

    2013-06-01

    The layer-by-layer (LbL) technique is a wet chemical method for the assembly of ultrathin films, with thicknesses up to 100 nm. This method is based on the successive transfer of molecular layers to a solid substrate that is dipped into cationic and anionic solutions in an alternating fashion. The adsorption is mainly driven by electrostatic interactions so that many molecular and nanomaterial systems can be engineered under this method. Moreover, it is inexpensive, can be easily performed, and does not demand sophisticated equipment or clean rooms. The most explored use of the LbL technique is to build up molecular devices for chemical sensing and energy conversion. Both applications require ultrathin films where specific elements must be organized with high control of thickness and spatial distribution, preferably in the nanolength and mesolength scales. In chemical sensors, the LbL technique is employed to assemble specific sensoactive materials such as conjugated polymers, enzymes, and immunological elements onto appropriated electrodes. Molecular recognition events are thus transduced by the assembled sensoactive layer. In energy-conversion devices, the LbL technique can be employed to fabricate different device's parts including electrodes, active layers, and auxiliary layers. In both applications, the devices' performance can be fully modulated and improved by simply varying film thickness and molecular architecture. The present review article highlights the main features of the LbL technique and provides a brief description of different (bio)chemical sensors, solar cells, and organic light-emitting diodes enabled by the LbL approach.

  13. Loads specification and embedded plate definition for the ITER cryoline system

    NASA Astrophysics Data System (ADS)

    Badgujar, S.; Benkheira, L.; Chalifour, M.; Forgeas, A.; Shah, N.; Vaghela, H.; Sarkar, B.

    2015-12-01

    ITER cryolines (CLs) are complex network of vacuum-insulated multi and single process pipe lines, distributed in three different areas at ITER site. The CLs will support different operating loads during the machine life-time; either considered as nominal, occasional or exceptional. The major loads, which form the design basis are inertial, pressure, temperature, assembly, magnetic, snow, wind, enforced relative displacement and are put together in loads specification. Based on the defined load combinations, conceptual estimation of reaction loads have been carried out for the lines located inside the Tokamak building. Adequate numbers of embedded plates (EPs) per line have been defined and integrated in the building design. The finalization of building EPs to support the lines, before the detailed design, is one of the major design challenges as the usual logic of the design may alter. At the ITER project level, it was important to finalize EPs to allow adequate design and timely availability of the Tokamak building. The paper describes the single loads, load combinations considered in load specification and the approach for conceptual load estimation and selection of EPs for Toroidal Field (TF) Cryoline as an example by converting the load combinations in two main load categories; pressure and seismic.

  14. 52. Neg. No.none, ca. 1950's, PhotographerUnknown, AERIAL VIEWS OF THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    52. Neg. No.-none, ca. 1950's, Photographer-Unknown, AERIAL VIEWS OF THE FORD MOTOR COMPANY ASSEMBLY PLANT, SOMETIME AFTER THE ADDITION OF THE NORTHERN WING - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  15. A modular assembling platform for manufacturing of microsystems by optical tweezers

    NASA Astrophysics Data System (ADS)

    Ksouri, Sarah Isabelle; Aumann, Andreas; Ghadiri, Reza; Prüfer, Michael; Baer, Sebastian; Ostendorf, Andreas

    2013-09-01

    Due to the increased complexity in terms of materials and geometries for microsystems new assembling techniques are required. Assembling techniques from the semiconductor industry are often very specific and cannot fulfill all specifications in more complex microsystems. Therefore, holographic optical tweezers are applied to manipulate structures in micrometer range with highest flexibility and precision. As is well known non-spherical assemblies can be trapped and controlled by laser light and assembled with an additional light modulator application, where the incident laser beam is rearranged into flexible light patterns in order to generate multiple spots. The complementary building blocks are generated by a two-photon-polymerization process. The possibilities of manufacturing arbitrary microstructures and the potential of optical tweezers lead to the idea of combining manufacturing techniques with manipulation processes to "microrobotic" processes. This work presents the manipulation of generated complex microstructures with optical tools as well as a storage solution for 2PP assemblies. A sample holder has been developed for the manual feeding of 2PP building blocks. Furthermore, a modular assembling platform has been constructed for an `all-in-one' 2PP manufacturing process as a dedicated storage system. The long-term objective is the automation process of feeding and storage of several different 2PP micro-assemblies to realize an automated assembly process.

  16. KENNEDY SPACE CENTER, FLA. - Workers in the Columbia Debris Hangar pull items from storage containers to transfer to storage in the Vehicle Assembly Building. About 83,000 pieces were shipped to KSC during search and recovery efforts in East Texas.

    NASA Image and Video Library

    2003-09-02

    KENNEDY SPACE CENTER, FLA. - Workers in the Columbia Debris Hangar pull items from storage containers to transfer to storage in the Vehicle Assembly Building. About 83,000 pieces were shipped to KSC during search and recovery efforts in East Texas.

  17. KSC-04pd1401

    NASA Image and Video Library

    2004-07-02

    KENNEDY SPACE CENTER, FLA. - NASCAR Busch Series race driver Tim Fedewa completes his tour of KSC with a view from an upper level of the Fixed Service Structure on Launch Pad 39A. The Vehicle Assembly Building is in the background. Fedewa is touring KSC for the Speed Channel TV show “NBS 24/7,” which is devoted to NASCAR. Other sites on his tour are the Launch Control Center, Vehicle Assembly Building and the Orbiter Processing Facility.

  18. Assembling oppositely charged lock and key responsive colloids: A mesoscale analog of adaptive chemistry

    PubMed Central

    Mihut, Adriana M.; Stenqvist, Björn; Lund, Mikael; Schurtenberger, Peter; Crassous, Jérôme J.

    2017-01-01

    We have seen a considerable effort in colloid sciences to copy Nature’s successful strategies to fabricate complex functional structures through self-assembly. This includes attempts to design colloidal building blocks and their intermolecular interactions, such as creating the colloidal analogs of directional molecular interactions, molecular recognition, host-guest systems, and specific binding. We show that we can use oppositely charged thermoresponsive particles with complementary shapes, such as spherical and bowl-shaped particles, to implement an externally controllable lock-and-key self-assembly mechanism. The use of tunable electrostatic interactions combined with the temperature-dependent size and shape and van der Waals interactions of these building blocks provides an exquisite control over the selectivity and specificity of the interactions and self-assembly process. The dynamic nature of the mechanism allows for reversibly cycling through various structures that range from weakly structured dense liquids to well-defined molecule-shaped clusters with different configurations through variations in temperature and ionic strength. We link this complex and dynamic self-assembly behavior to the relevant molecular interactions, such as screened Coulomb and van der Waals forces and the geometrical complementarity of the two building blocks, and discuss our findings in the context of the concepts of adaptive chemistry recently introduced to molecular systems. PMID:28929133

  19. Advanced Gas Turbine (AGT): Power-train system development

    NASA Technical Reports Server (NTRS)

    Helms, H. E.; Johnson, R. A.; Gibson, R. K.; Smith, L. B.

    1983-01-01

    Technical work on the design and effort leading to the testing of a 74.5 kW (100 hp) automotive gas turbine is described. The general effort was concentrated on building an engine for test starting in July. The buildup progressed with only routine problems and the engine was delivered to the test stand 9 July. In addition to the engine build effort, work continued in selected component areas. Ceramic turbine parts were built and tested. Burst tests of ceramic rotors show strengths are approaching that achieved in test bars; proof testing is required for acceptable strength ceramic vanes. Over 25 hours was accumulated on the combustor rig in three test modes: pilot nozzle only, start nozzle, and main nozzle operation. Satisfactory ignition was achieved for a wide range of starting speeds and the lean blowout limit was as low as 0.06 kg/b (0.14 lb/hr). Lean blowout was more a function of nozzle atomization than fuel/air ratio. A variety of cycle points were tested. Transition from start nozzle flow to main nozzle flow was done manually without difficulty. Regenerator parts were qualification tested without incident and the parts were assembled on schedule. Rig based performance matched first build requirements. Repeated failures in the harmonic drive gearbox during rig testing resulted in that concept being abandoned for an alternate scheme.

  20. Shape-specific nanostructured protein mimics from de novo designed chimeric peptides.

    PubMed

    Jiang, Linhai; Yang, Su; Lund, Reidar; Dong, He

    2018-01-30

    Natural proteins self-assemble into highly-ordered nanoscaled architectures to perform specific functions. The intricate functions of proteins have provided great impetus for researchers to develop strategies for designing and engineering synthetic nanostructures as protein mimics. Compared to the success in engineering fibrous protein mimetics, the design of discrete globular protein-like nanostructures has been challenging mainly due to the lack of precise control over geometric packing and intermolecular interactions among synthetic building blocks. In this contribution, we report an effective strategy to construct shape-specific nanostructures based on the self-assembly of chimeric peptides consisting of a coiled coil dimer and a collagen triple helix folding motif. Under salt-free conditions, we showed spontaneous self-assembly of the chimeric peptides into monodisperse, trigonal bipyramidal-like nanoparticles with precise control over the stoichiometry of two folding motifs and the geometrical arrangements relative to one another. Three coiled coil dimers are interdigitated on the equatorial plane while the two collagen triple helices are located in the axial position, perpendicular to the coiled coil plane. A detailed molecular model was proposed and further validated by small angle X-ray scattering experiments and molecular dynamics (MD) simulation. The results from this study indicated that the molecular folding of each motif within the chimeric peptides and their geometric packing played important roles in the formation of discrete protein-like nanoparticles. The peptide design and self-assembly mechanism may open up new routes for the construction of highly organized, discrete self-assembling protein-like nanostructures with greater levels of control over assembly accuracy.

  1. 14. INTERIOR DETAIL OF CONTROL PANEL IN BUILDING 1606. VIEW ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. INTERIOR DETAIL OF CONTROL PANEL IN BUILDING 1606. VIEW TO SOUTH. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  2. 17. INTERIOR DETAIL OF CONTROL PANEL IN BUILDING 1606. VIEW ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. INTERIOR DETAIL OF CONTROL PANEL IN BUILDING 1606. VIEW TO SOUTH. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  3. 12. INTERIOR DETAIL OF ELECTRICAL PANEL IN BUILDING 1606. VIEW ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. INTERIOR DETAIL OF ELECTRICAL PANEL IN BUILDING 1606. VIEW TO NORTH. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  4. 15. INTERIOR DETAIL OF CONTROL PANEL IN BUILDING 1606. VIEW ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. INTERIOR DETAIL OF CONTROL PANEL IN BUILDING 1606. VIEW TO NORTH. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  5. 16. INTERIOR DETAIL OF CONTROL PANEL IN BUILDING 1606. VIEW ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. INTERIOR DETAIL OF CONTROL PANEL IN BUILDING 1606. VIEW TO SOUTHWEST. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  6. 24. INTERIOR DETAIL OF BUILDING 1607, SHOWING BOMBS AND CRATES. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    24. INTERIOR DETAIL OF BUILDING 1607, SHOWING BOMBS AND CRATES. VIEW TO SOUTHWEST. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  7. General view taken inside of an assembly bay of the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view taken inside of an assembly bay of the Vehicle Assembly Building at the Kennedy Space Center. This view shows the Orbiter Discovery being lowered into position in preparation for being mated to the External Tank/Solid Rocket Booster assembly on the Mobile Launch Platform. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  8. Artistic view of VAB

    NASA Technical Reports Server (NTRS)

    2000-01-01

    A bundle of flexible pipes arcing toward the Vehicle Assembly Building (left) and Operations Support Building (right) presents an artistic design to travelers on nearby Kennedy Parkway and Saturn Causeway.

  9. Building 933935, oblique view to southwest showing, left to right, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Building 933-935, oblique view to southwest showing, left to right, rear doors to building 933, 934, 935, 90 mm lens. Building 934 in the center of complex. - Travis Air Force Base, Nuclear Weapons Assembly Plant 3, W Street, Armed Forces Special Weapons Project Q Area, Fairfield, Solano County, CA

  10. Digital Alchemy for Materials Design: Colloids and Beyond

    NASA Astrophysics Data System (ADS)

    van Anders, Greg; Klotsa, Daphne; Karas, Andrew; Dodd, Paul; Glotzer, Sharon

    Starting with the early alchemists, a holy grail of science has been to make desired materials by manipulating basic building blocks. Building blocks that show promise for assembling new complex materials can be synthesized at the nanoscale with attributes that would astonish the ancient alchemists in their versatility. However, this versatility means that connecting building-block attributes to bulk structure is both necessary for rationally engineering materials and difficult because building block attributes can be altered in many ways. We show how to exploit the malleability of colloidal nanoparticle ``elements'' to quantitatively link building-block attributes to bulk structure through a statistical thermodynamic framework we term ``digital alchemy''. We use this framework to optimize building blocks for a given target structure and to determine which building-block attributes are most important to control for self-assembly, through a set of novel thermodynamic response functions. We thereby establish direct links between the attributes of colloidal building blocks and the bulk structures they form. Moreover, our results give concrete solutions to the more general conceptual challenge of optimizing emergent behaviors in nature and can be applied to other types of matter.

  11. Strategies for Controlled Placement of Nanoscale Building Blocks

    PubMed Central

    2007-01-01

    The capability of placing individual nanoscale building blocks on exact substrate locations in a controlled manner is one of the key requirements to realize future electronic, optical, and magnetic devices and sensors that are composed of such blocks. This article reviews some important advances in the strategies for controlled placement of nanoscale building blocks. In particular, we will overview template assisted placement that utilizes physical, molecular, or electrostatic templates, DNA-programmed assembly, placement using dielectrophoresis, approaches for non-close-packed assembly of spherical particles, and recent development of focused placement schemes including electrostatic funneling, focused placement via molecular gradient patterns, electrodynamic focusing of charged aerosols, and others. PMID:21794185

  12. 21. INTERIOR DETAIL OF TON CONTAINER DEMILITARIZATION EQUIPMENT IN BUILDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. INTERIOR DETAIL OF TON CONTAINER DEMILITARIZATION EQUIPMENT IN BUILDING 1606. VIEW TO SOUTHWEST. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  13. 4. SOUTH AND WEST SIDES OF BUILDING 1601/1606/1607. VIEW TO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. SOUTH AND WEST SIDES OF BUILDING 1601/1606/1607. VIEW TO NORTH. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  14. 5. DETAIL OF EAST SIDE OF BUILDING 1601/1606/1607. VIEW TO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. DETAIL OF EAST SIDE OF BUILDING 1601/1606/1607. VIEW TO SOUTHWEST. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  15. 3. NORTH AND EAST SIDES OF BUILDING 1601/1606/1607. VIEW TO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. NORTH AND EAST SIDES OF BUILDING 1601/1606/1607. VIEW TO SOUTHWEST. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  16. 25. INTERIOR DETAIL OF BUILDING 1607, SHOWING BOMB CRATES AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    25. INTERIOR DETAIL OF BUILDING 1607, SHOWING BOMB CRATES AND SCALE. VIEW TO WEST. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  17. 1. ADMINISTRATIVE OFFICES WITH SHOWROOM AT GROUND LEVEL. VIEW TO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. ADMINISTRATIVE OFFICES WITH SHOWROOM AT GROUND LEVEL. VIEW TO SOUTH-SOUTHEAST. - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  18. View northeast of mould loft and plating cutting shop in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View northeast of mould loft and plating cutting shop in structural assembly shop (building no. 541) - Naval Base Philadelphia-Philadelphia Naval Shipyard, Structural Assembly Shop, League Island, Philadelphia, Philadelphia County, PA

  19. Mathematical modeling of HIV-like particle assembly in vitro.

    PubMed

    Liu, Yuewu; Zou, Xiufen

    2017-06-01

    In vitro, the recombinant HIV-1 Gag protein can generate spherical particles with a diameter of 25-30 nm in a fully defined system. It has approximately 80 building blocks, and its intermediates for assembly are abundant in geometry. Accordingly, there are a large number of nonlinear equations in the classical model. Therefore, it is difficult to compute values of geometry parameters for intermediates and make the mathematical analysis using the model. In this work, we develop a new model of HIV-like particle assembly in vitro by using six-fold symmetry of HIV-like particle assembly to decrease the number of geometry parameters. This method will greatly reduce computational costs and facilitate the application of the model. Then, we prove the existence and uniqueness of the positive equilibrium solution for this model with 79 nonlinear equations. Based on this model, we derive the interesting result that concentrations of all intermediates at equilibrium are independent of three important parameters, including two microscopic on-rate constants and the size of nucleating structure. Before equilibrium, these three parameters influence the concentration variation rates of all intermediates. We also analyze the relationship between the initial concentration of building blocks and concentrations of all intermediates. Furthermore, the bounds of concentrations of free building blocks and HIV-like particles are estimated. These results will be helpful to guide HIV-like particle assembly experiments and improve our understanding of the assembly dynamics of HIV-like particles in vitro. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. Structural design principles for delivery of bioactive components in nutraceuticals and functional foods.

    PubMed

    McClements, David Julian; Decker, Eric Andrew; Park, Yeonhwa; Weiss, Jochen

    2009-06-01

    There have been major advances in the design and fabrication of structured delivery systems for the encapsulation of nutraceutical and functional food components. A wide variety of delivery systems is now available, each with its own advantages and disadvantages for particular applications. This review begins by discussing some of the major nutraceutical and functional food components that need to be delivered and highlights the main limitations to their current utilization within the food industry. It then discusses the principles underpinning the rational design of structured delivery systems: the structural characteristics of the building blocks; the nature of the forces holding these building blocks together; and, the different ways of assembling these building blocks into structured delivery systems. Finally, we review the major types of structured delivery systems that are currently available to food scientists: lipid-based (simple, multiple, multilayer, and solid lipid particle emulsions); surfactant-based (simple micelles, mixed micelles, vesicles, and microemulsions) and biopolymer-based (soluble complexes, coacervates, hydrogel droplets, and particles). For each type of delivery system we describe its preparation, properties, advantages, and limitations.

  1. Pv-Thermal Solar Power Assembly

    DOEpatents

    Ansley, Jeffrey H.; Botkin, Jonathan D.; Dinwoodie, Thomas L.

    2001-10-02

    A flexible solar power assembly includes a flexible photovoltaic device attached to a flexible thermal solar collector. The solar power assembly can be rolled up for transport and then unrolled for installation on a surface, such as the roof or side wall of a building or other structure, by use of adhesive and/or other types of fasteners.

  2. Assembly of RNA nanostructures on supported lipid bilayers

    NASA Astrophysics Data System (ADS)

    Dabkowska, Aleksandra P.; Michanek, Agnes; Jaeger, Luc; Rabe, Michael; Chworos, Arkadiusz; Höök, Fredrik; Nylander, Tommy; Sparr, Emma

    2014-12-01

    The assembly of nucleic acid nanostructures with controlled size and shape has large impact in the fields of nanotechnology, nanomedicine and synthetic biology. The directed arrangement of nano-structures at interfaces is important for many applications. In spite of this, the use of laterally mobile lipid bilayers to control RNA three-dimensional nanostructure formation on surfaces remains largely unexplored. Here, we direct the self-assembly of RNA building blocks into three-dimensional structures of RNA on fluid lipid bilayers composed of cationic 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) or mixtures of zwitterionic 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine (DOPC) and cationic sphingosine. We demonstrate the stepwise supramolecular assembly of discrete building blocks through specific and selective RNA-RNA interactions, based on results from quartz crystal microbalance with dissipation (QCM-D), ellipsometry, fluorescence recovery after photobleaching (FRAP) and total internal reflection fluorescence microscopy (TIRF) experiments. The assembly can be controlled to give a densely packed single layer of RNA polyhedrons at the fluid lipid bilayer surface. We show that assembly of the 3D structure can be modulated by sequence specific interactions, surface charge and changes in the salt composition and concentration. In addition, the tertiary structure of the RNA polyhedron can be controllably switched from an extended structure to one that is dense and compact. The versatile approach to building up three-dimensional structures of RNA does not require modification of the surface or the RNA molecules, and can be used as a bottom-up means of nanofabrication of functionalized bio-mimicking surfaces.The assembly of nucleic acid nanostructures with controlled size and shape has large impact in the fields of nanotechnology, nanomedicine and synthetic biology. The directed arrangement of nano-structures at interfaces is important for many applications. In spite of this, the use of laterally mobile lipid bilayers to control RNA three-dimensional nanostructure formation on surfaces remains largely unexplored. Here, we direct the self-assembly of RNA building blocks into three-dimensional structures of RNA on fluid lipid bilayers composed of cationic 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) or mixtures of zwitterionic 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine (DOPC) and cationic sphingosine. We demonstrate the stepwise supramolecular assembly of discrete building blocks through specific and selective RNA-RNA interactions, based on results from quartz crystal microbalance with dissipation (QCM-D), ellipsometry, fluorescence recovery after photobleaching (FRAP) and total internal reflection fluorescence microscopy (TIRF) experiments. The assembly can be controlled to give a densely packed single layer of RNA polyhedrons at the fluid lipid bilayer surface. We show that assembly of the 3D structure can be modulated by sequence specific interactions, surface charge and changes in the salt composition and concentration. In addition, the tertiary structure of the RNA polyhedron can be controllably switched from an extended structure to one that is dense and compact. The versatile approach to building up three-dimensional structures of RNA does not require modification of the surface or the RNA molecules, and can be used as a bottom-up means of nanofabrication of functionalized bio-mimicking surfaces. Electronic supplementary information (ESI) available: Table with sequences of tRNA units used in this study; schematic structures of the RNA polyhedron and its building blocks; gel electrophoresis characterization of the RNA polyhedron and squares; AFM characterization of RNA tectosquare; schematic structures of RNA-9 and RNA-10 and their association with lipid bilayers; QCM-D frequency and dissipation data (as function of time) for adsorption of RNA polyhedrons, RNA squares and RNA9-10 TIRF images of RNA with Gelstar after photobleaching with analysis; Correlation plot in change of shear viscosity for TS3 and TO3-4 models for the stoichiometry of TS; QCM-D dissipation data for the sequential experiment in Fig. 5a; QCM-D and for the assembly of building blocks at the bilayer scaffold at varying bulk concentrations; QCM-D of adsorption of TS3. See DOI: 10.1039/c4nr05968a

  3. Molecular self-assembly using peptide nucleic acids.

    PubMed

    Berger, Or; Gazit, Ehud

    2017-01-01

    Peptide nucleic acids (PNAs) are extensively studied for the control of genetic expression since their design in the 1990s. However, the application of PNAs in nanotechnology is much more recent. PNAs share the specific base-pair recognition characteristic of DNA together with material-like properties of polyamides, both proteins and synthetic polymers, such as Kevlar and Nylon. The first application of PNA was in the form of PNA-amphiphiles, resulting in the formation of either lipid integrated structures, hydrogels or fibrillary assemblies. Heteroduplex DNA-PNA assemblies allow the formation of hybrid structures with higher stability as compared with pure DNA. A systematic screen for minimal PNA building blocks resulted in the identification of guanine-containing di-PNA assemblies and protected guanine-PNA monomer spheres showing unique optical properties. Finally, the co-assembly of PNA with thymine-like three-faced cyanuric acid allowed the assembly of poly-adenine PNA into fibers. In summary, we believe that PNAs represent a new and important family of building blocks which converges the advantages of both DNA- and peptide-nanotechnologies. © 2016 Wiley Periodicals, Inc.

  4. KENNEDY SPACE CENTER, FLA. - Storage boxes and other containers of Columbia debris wait in the Columbia Debris Hangar for transfer to storage in the Vehicle Assembly Building. About 83,000 pieces were shipped to KSC during search and recovery efforts in East Texas.

    NASA Image and Video Library

    2003-09-02

    KENNEDY SPACE CENTER, FLA. - Storage boxes and other containers of Columbia debris wait in the Columbia Debris Hangar for transfer to storage in the Vehicle Assembly Building. About 83,000 pieces were shipped to KSC during search and recovery efforts in East Texas.

  5. Spontaneous self-assembly of a giant spherical metal-oxide Keplerate: addition of one building block induces "immediate" formation of the complementary one from a constitutional dynamic library.

    PubMed

    Schäffer, Christian; Todea, Ana Maria; Gouzerh, Pierre; Müller, Achim

    2012-01-11

    The addition of dinuclear {Mo(2)} units to a dynamic library containing molybdates results in the spontaneous self-assembly of a giant spherical metal-oxide species of the type {(Mo)Mo(5)}(12){Mo(2)}(30) while the required pentagonal {(Mo)Mo(5)} building blocks are "immediately" formed. This journal is © The Royal Society of Chemistry 2012

  6. Colibactin assembly line enzymes use S-adenosylmethionine to build a cyclopropane ring

    PubMed Central

    Zha, Li; Jiang, Yindi; Henke, Matthew T.; Wilson, Matthew R.; Wang, Jennifer X.; Kelleher, Neil L.; Balskus, Emily P.

    2017-01-01

    Despite containing an α-amino acid, the versatile cofactor S-adenosylmethionine (SAM) is not a known building block for non-ribosomal peptide synthetase (NRPS) assembly lines. Here we report an unusual NRPS module from colibactin biosynthesis that uses SAM for amide bond formation and subsequent cyclopropanation. Our findings showcase a new use for SAM and reveal a novel biosynthetic route to a functional group that likely mediates colibactin’s genotoxicity. PMID:28805802

  7. Selective self-assembly of adenine-silver nanoparticles forms rings resembling the size of cells

    NASA Astrophysics Data System (ADS)

    Choi, Sungmoon; Park, Soonyoung; Yang, Seon-Ah; Jeong, Yujin; Yu, Junhua

    2015-12-01

    Self-assembly has played critical roles in the construction of functional nanomaterials. However, the structure of the macroscale multicomponent materials built by the self-assembly of nanoscale building blocks is hard to predict due to multiple intermolecular interactions of great complexity. Evaporation of solvents is usually an important approach to induce kinetically stable assemblies of building blocks with a large-scale specific arrangement. During such a deweting process, we tried to monitor the possible interactions between silver nanoparticles and nucleobases at a larger scale by epifluorescence microscopy, thanks to the doping of silver nanoparticles with luminescent silver nanodots. ssDNA oligomer-stabilized silver nanoparticles and adenine self-assemble to form ring-like compartments similar to the size of modern cells. However, the silver ions only dismantle the self-assembly of adenine. The rings are thermodynamically stable as the drying process only enrich the nanoparticles-nucleobase mixture to a concentration that activates the self-assembly. The permeable membrane-like edge of the ring is composed of adenine filaments glued together by silver nanoparticles. Interestingly, chemicals are partially confined and accumulated inside the ring, suggesting that this might be used as a microreactor to speed up chemical reactions during a dewetting process.

  8. Dispersal and the transition to sympatry in vertebrates

    PubMed Central

    Pigot, Alex L.; Tobias, Joseph A.

    2015-01-01

    Under allopatric speciation models, a key step in the build-up of species richness is population dispersal leading to the co-occurrence of previously geographically isolated forms. Despite its central importance for community assembly, the extent to which the transition from spatial segregation (allopatry or parapatry) to coexistence (sympatry) is a predictable process, or alternatively one governed by chance and the vagaries of biogeographic history, remains poorly understood. Here, we use estimated divergence times and current patterns of geographical range overlap among sister species to explore the evolution of sympatry in vertebrates. We show that rates of transition to sympatry vary predictably according to ecology, being faster in marine or strongly dispersive terrestrial clades. This association with organism vagility is robust to the relative frequency of geographical speciation modes and consistent across taxonomic scales and metrics of dispersal ability. These findings reject neutral models of dispersal assembly based simply on evolutionary age and are not predicted by the main alternative view that range overlap is primarily constrained by biotic interactions. We conclude that species differences in dispersal limitation are fundamental in organizing the assembly of ecological communities and shaping broad-scale patterns of biodiversity over space and time. PMID:25621326

  9. Block Copolymer Micelles for Photonic Fluids and Crystals.

    PubMed

    Poutanen, Mikko; Guidetti, Giulia; Gröschel, Tina I; Borisov, Oleg V; Vignolini, Silvia; Ikkala, Olli; Gröschel, Andre H

    2018-04-24

    Block copolymer micelles (BCMs) are self-assembled nanoparticles in solution with a collapsed core and a brush-like stabilizing corona typically in the size range of tens of nanometers. Despite being widely studied in various fields of science and technology, their ability to form structural colors at visible wavelength has not received attention, mainly due to the stringent length requirements of photonic lattices. Here, we describe the precision assembly of BCMs with superstretched corona, yet with narrow size distribution to qualify as building blocks for tunable and reversible micellar photonic fluids (MPFs) and micellar photonic crystals (MPCs). The BCMs form free-flowing MPFs with an average interparticle distance of 150-300 nm as defined by electrosteric repulsion arising from the highly charged and stretched corona. Under quiescent conditions, millimeter-sized MPCs with classical FCC lattice grow within the photonic fluid-medium upon refinement of the positional order of the BCMs. We discuss the generic properties of MPCs with special emphasis on surprisingly narrow reflected wavelengths with full width at half-maximum (fwhm) as small as 1 nm. We expect this concept to open a generic and facile way for self-assembled tunable micellar photonic structures.

  10. Mobius Assembly: A versatile Golden-Gate framework towards universal DNA assembly

    PubMed Central

    Andreou, Andreas I.

    2018-01-01

    Synthetic biology builds upon the foundation of engineering principles, prompting innovation and improvement in biotechnology via a design-build-test-learn cycle. A community-wide standard in DNA assembly would enable bio-molecular engineering at the levels of predictivity and universality in design and construction that are comparable to other engineering fields. Golden Gate Assembly technology, with its robust capability to unidirectionally assemble numerous DNA fragments in a one-tube reaction, has the potential to deliver a universal standard framework for DNA assembly. While current Golden Gate Assembly frameworks (e.g. MoClo and Golden Braid) render either high cloning capacity or vector toolkit simplicity, the technology can be made more versatile—simple, streamlined, and cost/labor-efficient, without compromising capacity. Here we report the development of a new Golden Gate Assembly framework named Mobius Assembly, which combines vector toolkit simplicity with high cloning capacity. It is based on a two-level, hierarchical approach and utilizes a low-frequency cutter to reduce domestication requirements. Mobius Assembly embraces the standard overhang designs designated by MoClo, Golden Braid, and Phytobricks and is largely compatible with already available Golden Gate part libraries. In addition, dropout cassettes encoding chromogenic proteins were implemented for cost-free visible cloning screening that color-code different cloning levels. As proofs of concept, we have successfully assembled up to 16 transcriptional units of various pigmentation genes in both operon and multigene arrangements. Taken together, Mobius Assembly delivers enhanced versatility and efficiency in DNA assembly, facilitating improved standardization and automation. PMID:29293531

  11. Modeling of DNA-Mediated Self-Assembly from Anisotropic Nanoparticles: A Molecular Dynamics Study

    NASA Astrophysics Data System (ADS)

    Millan, Jaime; Girard, Martin; Brodin, Jeffrey; O'Brien, Matt; Mirkin, Chad; Olvera de La Cruz, Monica

    The programmable selectivity of DNA recognition constitutes an elegant scheme to self-assemble a rich variety of superlattices from versatile nanoscale building blocks, where the natural interactions between building blocks are traded by complementary DNA hybridization interactions. Recently, we introduced and validated a scale-accurate coarse-grained model for a molecular dynamics approach that captures the dynamic nature of DNA hybridization events and reproduces the experimentally-observed crystallization behavior of various mixtures of spherical DNA-modified nanoparticles. Here, we have extended this model to robustly reproduce the assembly of nanoparticles with the anisotropic shapes observed experimentally. In particular, we are interested in two different particle types: (i) regular shapes, namely the cubic and octahedral polyhedra shapes commonly observed in gold nanoparticles, and (ii) irregular shapes akin to those exhibited by enzymes. Anisotropy in shape can provide an analog to the atomic orbitals exhibited by conventional atomic crystals. We present results for the assembly of enzymes or anisotropic nanoparticles and the co-assembly of enzymes and nanoparticles.

  12. Two-dimensional honeycomb network through sequence-controlled self-assembly of oligopeptides.

    PubMed

    Abb, Sabine; Harnau, Ludger; Gutzler, Rico; Rauschenbach, Stephan; Kern, Klaus

    2016-01-12

    The sequence of a peptide programs its self-assembly and hence the expression of specific properties through non-covalent interactions. A large variety of peptide nanostructures has been designed employing different aspects of these non-covalent interactions, such as dispersive interactions, hydrogen bonding or ionic interactions. Here we demonstrate the sequence-controlled fabrication of molecular nanostructures using peptides as bio-organic building blocks for two-dimensional (2D) self-assembly. Scanning tunnelling microscopy reveals changes from compact or linear assemblies (angiotensin I) to long-range ordered, chiral honeycomb networks (angiotensin II) as a result of removal of steric hindrance by sequence modification. Guided by our observations, molecular dynamic simulations yield atomistic models for the elucidation of interpeptide-binding motifs. This new approach to 2D self-assembly on surfaces grants insight at the atomic level that will enable the use of oligo- and polypeptides as large, multi-functional bio-organic building blocks, and opens a new route towards rationally designed, bio-inspired surfaces.

  13. Phosphorus-supported ligands for the assembly of multimetal architectures.

    PubMed

    Chandrasekhar, Vadapalli; Murugesapandian, Balasubramanian

    2009-08-18

    Modeled after boron-based scorpionate ligands, acyclic and cyclic phosphorus-containing compounds possessing reactive groups can serve as excellent precursors for the assembly of novel phosphorus-supported ligands that can coordinate multiple sites. In such ligands, the phosphorus atom does not have any role in coordination but is used as a structural support to assemble one or more coordination platforms. In this Account, we describe the utility of inorganic heterocyclic rings such as cyclophosphazenes and carbophosphazenes as well as acyclic phosphorus-containing compounds such as (S)PCl(3), RP(O)Cl(2), and R(2)P(O)Cl for building such multisite coordination platforms. We can modulate the number and orientation of such coordination platforms through the choice of the phosphorus-containing precursor. This methodology is quite general and modular and allows the creation of well-defined libraries of multisite coordination ligands. Phosphorus-supported pyrazolyl ligands are quite useful for building multimetallic architectures. Some of these ligands are prone to P-N bond hydrolysis upon metalation, but we have exploited the P-N bond sensitivity to generate hydrolyzed ligands in situ, which are useful to build multimetal assemblies. In addition, the intimate relationship between small molecule cyclophosphazenes and the corresponding pendant cyclophosphazene-containing polymer systems facilitated our design of polymer-supported catalysts for phosphate ester hydrolysis, plasmid DNA modification, and C-C bond formation reactions. Phosphorus hydrazides containing reactive amine groups are ideal precursors for integration into more complex ligand systems. The ligand (S)P[N(Me)N=CH-C(6)H(4)-2-OH](3) (LH(3)) contains six coordination sites, and its coordination response depends upon the oxidation state of the metal ion employed. LH(3) reacts with divalent transition metal ions to afford neutral trimetallic derivatives L(2)M(3), where the three metal ions are arranged in a perfectly linear manner in many cases. Incorporating an additional methoxy group into LH(3) affords the ligand (S)P[N(Me)N=CH-C(6)H(3)-2-OH-3-OMe](3) (L'H(3)), which contains nine coordination sites: three imino nitrogen atoms, three phenolate oxygen atoms, and three methoxy oxygen atoms. The reaction of L'H(3) with transition metal salts in 1:1 ratio leads to the in situ formation of a metalloligand (L'M), which on further treatment with lanthanide salts gives heterobimetallic trinuclear cationic complexes [L'(2)M(2)Ln](+) containing a M-Ln-M linear array (M = transition metal ion in a +2 oxidation state). Many of these 3d-4f compounds behave as single-molecule magnets at low temperatures. Although challenges remain in the development of synthetic methods and in the architectural control of the coordination platforms, we see opportunities for further research into coordination platforms supported by main group elements such as phosphorus. As we have shown in this Account, one potential disadvantage, sensitivity of P-N bonds to hydrolysis, can be used successfully to build larger assemblies.

  14. Technology Solutions Case Study: Hygrothermal Performance of a Double-Stud Cellulose Wall

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2015-06-01

    Moisture problems within the building shell can be caused by a number of factors including excess interior moisture that is transported into the wall through air leakage and vapor drive, bulk water intrusion from leaks and wind-driven rain, capillary action from concrete to wood connections, and through wetted building materials such as siding wetted from rain splash back. With the increasing thickness of walls, moisture issues could increase. Several builders have successfully used “double-wall” systems to more practically achieve higher R-values in thicker framed walls. A double wall typically consists of a load-bearing external frame wall constructed with 2 ×more » 4 framing at 16 in. on center using conventional methods. After the building is enclosed, an additional frame wall is constructed several inches inside the load-bearing wall. Several researchers have used moisture modeling software to conduct extensive analysis of these assemblies; however, little field research has been conducted to validate the results. In this project, the Building America research team Consortium for Advanced Residential Buildings monitored a double-stud assembly in climate zone 5A to determine the accu¬racy of moisture modeling and make recommendations to ensure durable and efficient assemblies.« less

  15. sts095-s-015

    NASA Image and Video Library

    2009-09-23

    STS095-S-015 (7 Nov. 1998) --- The main landing gear of the space shuttle Discovery is about to touch down on Runway 33 at the Shuttle Landing Facility at the Kennedy Space Center (KSC). Main gear touchdown was at 12:04 p.m. (EST), landing on orbit 135. Discovery returned to Earth with its crew of five astronauts and two payload specialists to successfully complete the nine-day mission. A Shuttle Training Aircraft (STA) is at top center, with the Vehicle Assembly Building (VAB) at right edge of frame. Onboard were astronauts Curtis L. Brown Jr., Steven W. Lindsey, Scott F. Parazynski, Stephen K. Robinson, Pedro Duque and payload specialists Chiaki Naito-Mukai and United States Senator John H. Glenn Jr. Duque represents the European Space Agency (ESA) and Mukai is with Japan's National Space Development Agency (NASDA). Photo credit: NASA

  16. Saturn Apollo Program

    NASA Image and Video Library

    1963-01-01

    In this photograph, the Saturn I S-I stages for the SA-4, SA-6, and SA-7 missions were being assembled at the Fabrication and Assembly Engineering Division in the Marshall Space Flight Center building 4705, January 13, 1963.

  17. 73. SECOND FLOOR, HEATER ROOM, BAY 31/5 SOUTH, WITH FANFORCED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    73. SECOND FLOOR, HEATER ROOM, BAY 31/5 SOUTH, WITH FAN-FORCED HOT AIR HEATER; TO SOUTHEAST - Ford Motor Company Edgewater Assembly Plant, Assembly Building, 309 River Road, Edgewater, Bergen County, NJ

  18. DNA Assembly Line for Nano-Construction

    ScienceCinema

    Oleg Gang

    2017-12-09

    Building on the idea of using DNA to link up nanoparticles scientists at Brookhaven National Lab have designed a molecular assembly line for high-precision nano-construction. Nanofabrication is essential for exploiting the unique properties of nanoparticl

  19. STS-71 hardware assembly view

    NASA Technical Reports Server (NTRS)

    1994-01-01

    Lockheed Space Operations Company workers in the Extended Duration Orbiter (EDO) Facility, located inside the Vehicle Assembly Building (VAB), carefully hoist the Orbiter Docking System (ODS) from its shipping container into a test stand. The ODS was ship

  20. General view of the Space Shuttle Main Engine (SSME) assembly ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of the Space Shuttle Main Engine (SSME) assembly with the expansion nozzle removed and resting on a cushioned mat on the floor of the SSME Processing Facility. The most prominent features in this view are the Low-Pressure Fuel Turbopump (LPFTP) on the upper left of the engine assembly, the LPFTP Discharge Duct looping around the assembly, the Gimbal Bearing on the top center of the assembly, the Electrical Interface Panel sits just below the Gimbal Bearing and the Low-Pressure Oxidizer Turbopump is mounted on the top right of the engine assembly in this view. - Space Transportation System, Space Shuttle Main Engine, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  1. 120. NORTH PLANT GB BULK STORAGE BUILDING AND AMMUNITION DEMOLITION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    120. NORTH PLANT GB BULK STORAGE BUILDING AND AMMUNITION DEMOLITION FACILITY AT CENTER AND CASE FILLING PLANT/CLUSTER ASSEMBLY BUILDING (BUILDING 1601/1606) IN BACKGROUND, FROM GB MANUFACTURING PLANT. VIEW TO WEST. - Rocky Mountain Arsenal, Bounded by Ninety-sixth Avenue & Fifty-sixth Avenue, Buckley Road, Quebec Street & Colorado Highway 2, Commerce City, Adams County, CO

  2. General view of a Space Shuttle Main Engine (SSME) mounted ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of a Space Shuttle Main Engine (SSME) mounted on an SSME engine handler, taken in the SSME Processing Facility at Kennedy Space Center. The most prominent features of the engine assembly in this view are the Low-Pressure Fuel Turbopump Discharge Duct looping around the right side and underneath the assembly, the High-Pressure Fuel Turbopump located on the lower left portion of the assembly, the Engine Controller and Main Fuel Valve Hydraulic Actuator located on the upper portion of the assembly and the Low-Pressure Oxidizer Turbopump Discharge Duct at the top of the engine assembly in this view. - Space Transportation System, Space Shuttle Main Engine, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  3. Estimation of vulnerability functions based on a global earthquake damage database

    NASA Astrophysics Data System (ADS)

    Spence, R. J. S.; Coburn, A. W.; Ruffle, S. J.

    2009-04-01

    Developing a better approach to the estimation of future earthquake losses, and in particular to the understanding of the inherent uncertainties in loss models, is vital to confidence in modelling potential losses in insurance or for mitigation. For most areas of the world there is currently insufficient knowledge of the current building stock for vulnerability estimates to be based on calculations of structural performance. In such areas, the most reliable basis for estimating vulnerability is performance of the building stock in past earthquakes, using damage databases, and comparison with consistent estimates of ground motion. This paper will present a new approach to the estimation of vulnerabilities using the recently launched Cambridge University Damage Database (CUEDD). CUEDD is based on data assembled by the Martin Centre at Cambridge University since 1980, complemented by other more-recently published and some unpublished data. The database assembles in a single, organised, expandable and web-accessible database, summary information on worldwide post-earthquake building damage surveys which have been carried out since the 1960's. Currently it contains data on the performance of more than 750,000 individual buildings, in 200 surveys following 40 separate earthquakes. The database includes building typologies, damage levels, location of each survey. It is mounted on a GIS mapping system and links to the USGS Shakemaps of each earthquake which enables the macroseismic intensity and other ground motion parameters to be defined for each survey and location. Fields of data for each building damage survey include: · Basic earthquake data and its sources · Details of the survey location and intensity and other ground motion observations or assignments at that location · Building and damage level classification, and tabulated damage survey results · Photos showing typical examples of damage. In future planned extensions of the database information on human casualties will also be assembled. The database also contains analytical tools enabling data from similar locations, building classes or ground motion levels to be assembled and thus vulnerability relationships derived for any chosen ground motion parameter, for a given class of building, and for particular countries or regions. The paper presents examples of vulnerability relationships for particular classes of buildings and regions of the world, together with the estimated uncertainty ranges. It will discuss the applicability of such vulnerability functions in earthquake loss assessment for insurance purposes or for earthquake risk mitigation.

  4. KSC-00pp0858

    NASA Image and Video Library

    2000-06-29

    Inside the Vehicle Assembly Building, the forward section of a solid rocket booster (SRB) sits on top of the rest of the stack for mating. The forward section of each booster, from nose cap to forward skirt contains avionics, a sequencer, forward separation motors, a nose cone separation system, drogue and main parachutes, a recovery beacon, a recovery light, a parachute camera on selected flights and a range safety system. Each SRB weighs approximately 1.3 million pounds at launch. The SRB is part of the stack for Space Shuttle Discovery and the STS-92 mission, scheduled for launch Oct. 5, from Launch Pad 39A, on the fifth flight to the International Space Station

  5. KSC00pp0858

    NASA Image and Video Library

    2000-06-29

    Inside the Vehicle Assembly Building, the forward section of a solid rocket booster (SRB) sits on top of the rest of the stack for mating. The forward section of each booster, from nose cap to forward skirt contains avionics, a sequencer, forward separation motors, a nose cone separation system, drogue and main parachutes, a recovery beacon, a recovery light, a parachute camera on selected flights and a range safety system. Each SRB weighs approximately 1.3 million pounds at launch. The SRB is part of the stack for Space Shuttle Discovery and the STS-92 mission, scheduled for launch Oct. 5, from Launch Pad 39A, on the fifth flight to the International Space Station

  6. Kinematical simulation of robotic complex operation for implementing full-scale additive technologies of high-end materials, composites, structures, and buildings

    NASA Astrophysics Data System (ADS)

    Antsiferov, S. I.; Eltsov, M. Iu; Khakhalev, P. A.

    2018-03-01

    This paper considers a newly designed electronic digital model of a robotic complex for implementing full-scale additive technologies, funded under a Federal Target Program. The electronic and digital model was used to solve the problem of simulating the movement of a robotic complex using the NX CAD/CAM/CAE system. The virtual mechanism was built and the main assemblies, joints, and drives were identified as part of solving the problem. In addition, the maximum allowed printable area size was identified for the robotic complex, and a simulation of printing a rectangular-shaped article was carried out.

  7. Cluster-assembled metallic glasses

    PubMed Central

    2013-01-01

    A bottom-up approach to nanofabricate metallic glasses from metal clusters as building blocks is presented. Considering metallic glasses as a subclass of cluster-assembled materials, the relation between the two lively fields of metal clusters and metallic glasses is pointed out. Deposition of selected clusters or collections of them, generated by state-of-the-art cluster beam sources, could lead to the production of a well-defined amorphous material. In contrast to rapidly quenched glasses where only the composition of the glass can be controlled, in cluster-assembled glasses, one can precisely control the structural building blocks. Comparing properties of glasses with similar compositions but differing in building blocks and therefore different in structure will facilitate the study of structure–property correlation in metallic glasses. This bottom-up method provides a novel alternative path to the synthesis of glassy alloys and will contribute to improving fundamental understanding in the field of metallic glasses. It may even permit the production of glassy materials for alloys that cannot be quenched rapidly enough to circumvent crystallization. Additionally, gaining deeper insight into the parameters governing the structure–property relation in metallic glasses can have a great impact on understanding and design of other cluster-assembled materials. PMID:23899019

  8. Lipid self-assembly and lectin-induced reorganization of the plasma membrane.

    PubMed

    Sych, Taras; Mély, Yves; Römer, Winfried

    2018-05-26

    The plasma membrane represents an outstanding example of self-organization in biology. It plays a vital role in protecting the integrity of the cell interior and regulates meticulously the import and export of diverse substances. Its major building blocks are proteins and lipids, which self-assemble to a fluid lipid bilayer driven mainly by hydrophobic forces. Even if the plasma membrane appears-globally speaking-homogeneous at physiological temperatures, the existence of specialized nano- to micrometre-sized domains of raft-type character within cellular and synthetic membrane systems has been reported. It is hypothesized that these domains are the origin of a plethora of cellular processes, such as signalling or vesicular trafficking. This review intends to highlight the driving forces of lipid self-assembly into a bilayer membrane and the formation of small, transient domains within the plasma membrane. The mechanisms of self-assembly depend on several factors, such as the lipid composition of the membrane and the geometry of lipids. Moreover, the dynamics and organization of glycosphingolipids into nanometre-sized clusters will be discussed, also in the context of multivalent lectins, which cluster several glycosphingolipid receptor molecules and thus create an asymmetric stress between the two membrane leaflets, leading to tubular plasma membrane invaginations.This article is part of the theme issue 'Self-organization in cell biology'. © 2018 The Author(s).

  9. KENNEDY SPACE CENTER, FLA. - Employees file around table displays under a tent near the Vehicle Assembly Building. Many vendors displayed their products during the Spaceport Super Safety and Health Day at KSC, an annual event dedicated to reinforcing safe and healthful behaviors in the workforce.

    NASA Image and Video Library

    2003-10-15

    KENNEDY SPACE CENTER, FLA. - Employees file around table displays under a tent near the Vehicle Assembly Building. Many vendors displayed their products during the Spaceport Super Safety and Health Day at KSC, an annual event dedicated to reinforcing safe and healthful behaviors in the workforce.

  10. Storm Clouds Roll In Over The Vehicle Assembly Building

    NASA Image and Video Library

    2009-07-12

    Storm clouds roll in over the NASA Vehicle Assembly building moments after STS-127 Space Shuttle Launch Director Pete Nickolenko and the launch team called the launch a "No Go" due to weather conditions at the NASA Kennedy Space Center in Cape Canaveral, Florida, Sunday, July 12, 2009. Endeavour will be launching with the crew of STS-127 on a 16-day mission that will feature five spacewalks and complete construction of the Japan Aerospace Exploration Agency's Kibo laboratory. Photo Credit: (NASA/Bill Ingalls)

  11. Storm Clouds Roll In Over The Vehicle Assembly Building

    NASA Image and Video Library

    2009-07-11

    Storm clouds roll in over the NASA Vehicle Assembly building moments after STS-127 Space Shuttle Launch Director Pete Nickolenko and the launch team called the launch a "No Go" due to weather conditions at the NASA Kennedy Space Center in Cape Canaveral, Florida, Sunday, July 12, 2009. Endeavour will be launching with the crew of STS-127 on a 16-day mission that will feature five spacewalks and complete construction of the Japan Aerospace Exploration Agency's Kibo laboratory. Photo Credit: (NASA/Bill Ingalls)

  12. KENNEDY SPACE CENTER, FLA. - A worker in the Columbia Debris Hangar sorts bagged items of Columbia debris that will be transferred to storage in the Vehicle Assembly Building. About 83,000 pieces were shipped to KSC during search and recovery efforts in East Texas.

    NASA Image and Video Library

    2003-09-02

    KENNEDY SPACE CENTER, FLA. - A worker in the Columbia Debris Hangar sorts bagged items of Columbia debris that will be transferred to storage in the Vehicle Assembly Building. About 83,000 pieces were shipped to KSC during search and recovery efforts in East Texas.

  13. KENNEDY SPACE CENTER, FLA. - Workers in the Columbia Debris Hangar move some of the STS-107 debris into boxes for transfer to storage in the Vehicle Assembly Building. About 83,000 pieces were shipped to KSC during search and recovery efforts in East Texas.

    NASA Image and Video Library

    2003-09-02

    KENNEDY SPACE CENTER, FLA. - Workers in the Columbia Debris Hangar move some of the STS-107 debris into boxes for transfer to storage in the Vehicle Assembly Building. About 83,000 pieces were shipped to KSC during search and recovery efforts in East Texas.

  14. KENNEDY SPACE CENTER, FLA. - Storage boxes filled with Columbia debris (left) await transfer to storage in the Vehicle Assembly Building. Empty boxes at right wait to be filled with more of the approximately 83,000 pieces shipped to KSC during search and recovery efforts in East Texas.

    NASA Image and Video Library

    2003-09-02

    KENNEDY SPACE CENTER, FLA. - Storage boxes filled with Columbia debris (left) await transfer to storage in the Vehicle Assembly Building. Empty boxes at right wait to be filled with more of the approximately 83,000 pieces shipped to KSC during search and recovery efforts in East Texas.

  15. KENNEDY SPACE CENTER, FLA. - Workers in the Columbia Debris Hangar record the first items of the STS-107 debris to be transferred to storage in the Vehicle Assembly Building. About 83,000 pieces were shipped to KSC during search and recovery efforts in East Texas.

    NASA Image and Video Library

    2003-09-02

    KENNEDY SPACE CENTER, FLA. - Workers in the Columbia Debris Hangar record the first items of the STS-107 debris to be transferred to storage in the Vehicle Assembly Building. About 83,000 pieces were shipped to KSC during search and recovery efforts in East Texas.

  16. Building No. 5, Main Building; Building NO. 9, Guard House ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Building No. 5, Main Building; Building NO. 9, Guard House (left). Viewed from across corner Lakeside Avenue and Main Street - Thomas A. Edison Laboratories, Main Street & Lakeside Avenue, West Orange, Essex County, NJ

  17. Contextual view of building no. 541, looking northeast. Structure no. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view of building no. 541, looking northeast. Structure no. 1043 in foreground. - Naval Base Philadelphia-Philadelphia Naval Shipyard, Structural Assembly Shop, League Island, Philadelphia, Philadelphia County, PA

  18. General view of the Space Shuttle Main Engine (SSME) assembly ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of the Space Shuttle Main Engine (SSME) assembly with the expansion nozzle removed and resting on a cushioned mat on the floor of the SSME Processing Facility. The most prominent features in this view are the Low-pressure oxidizer Turbopump discharge Duct looping from the upper left side of the engine assembly to the lower left side of the assembly, the Low-Pressure Fuel Turbopump (LPFTP) is on the upper left of the assembly in this view and the LPFTP Discharge Duct loops from the upper left to upper right then turns back and down the assembly to the High-Pressure Fuel Turbopump on the lower right of the assembly. The Engine Controller and the Main fuel Valve Hydraulic Actuator are on the lower left portion of the assembly. The vertical rod that is in the approximate center of the engine assembly is a piece of ground support equipment call a Gimbal Actuator Replacement Strut which are used on the SSMEs when they are not installed in an orbiter. - Space Transportation System, Space Shuttle Main Engine, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  19. Detail, oblique view to northeast atop building 935 showing exposed ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail, oblique view to northeast atop building 935 showing exposed roof sections of buildings 934 (center) and 933 (left), 90 mm lens. - Travis Air Force Base, Nuclear Weapons Assembly Plant 3, W Street, Armed Forces Special Weapons Project Q Area, Fairfield, Solano County, CA

  20. Creating Sub-50 Nm Nanofluidic Junctions in PDMS Microfluidic Chip via Self-Assembly Process of Colloidal Particles

    PubMed Central

    Wei, Xi; Syed, Abeer; Mao, Pan; Han, Jongyoon; Song, Yong-Ak

    2016-01-01

    Polydimethylsiloxane (PDMS) is the prevailing building material to make microfluidic devices due to its ease of molding and bonding as well as its transparency. Due to the softness of the PDMS material, however, it is challenging to use PDMS for building nanochannels. The channels tend to collapse easily during plasma bonding. In this paper, we present an evaporation-driven self-assembly method of silica colloidal nanoparticles to create nanofluidic junctions with sub-50 nm pores between two microchannels. The pore size as well as the surface charge of the nanofluidic junction is tunable simply by changing the colloidal silica bead size and surface functionalization outside of the assembled microfluidic device in a vial before the self-assembly process. Using the self-assembly of nanoparticles with a bead size of 300 nm, 500 nm, and 900 nm, it was possible to fabricate a porous membrane with a pore size of ~45 nm, ~75 nm and ~135 nm, respectively. Under electrical potential, this nanoporous membrane initiated ion concentration polarization (ICP) acting as a cation-selective membrane to concentrate DNA by ~1,700 times within 15 min. This non-lithographic nanofabrication process opens up a new opportunity to build a tunable nanofluidic junction for the study of nanoscale transport processes of ions and molecules inside a PDMS microfluidic chip. PMID:27023724

  1. Automated glycan assembly of xyloglucan oligosaccharides.

    PubMed

    Dallabernardina, Pietro; Schuhmacher, Frank; Seeberger, Peter H; Pfrengle, Fabian

    2016-01-07

    We report the automated glycan assembly of oligosaccharide fragments related to the hemicellulose xyloglucan (XG). Iterative addition of monosaccharide and disaccharide building blocks to a solid support provided seven cellulose and xyloglucan fragments including XXGG- and XXXG-type oligosaccharides.

  2. 8. VIEW OF ROOM 101 (ASSEMBLY ROOM) FROM NORTHEAST CORNER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. VIEW OF ROOM 101 (ASSEMBLY ROOM) FROM NORTHEAST CORNER SHOWING FLEXIBLE AIR-CONDITIONING DUCT - Vandenberg Air Force Base, Space Launch Complex 3, Vehicle Support Building, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  3. 3. Peeler Shed, SE side, with blower assembly. This structure ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Peeler Shed, SE side, with blower assembly. This structure was need to move back to the Chipper Building for processing. - Pacific Creosoting Plant, Log Peeling Operation, 5350 Creosote Place, Northeast, Bremerton, Kitsap County, WA

  4. Assembly Line of Stars

    NASA Image and Video Library

    2010-05-06

    This image from NASA Herschel, in the constellation of Vulpecula, shows an entire assembly line of newborn stars. The diffuse glow reveals the widespread cold reservoir of raw material that our Milky Way galaxy has in stock for building stars.

  5. 107. JOB NO. 1347T, SHEET IS, 1930, FORD MOTOR COMPANY; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    107. JOB NO. 1347-T, SHEET IS, 1930, FORD MOTOR COMPANY; REINFORCEMENT OF GRAVITY TANK - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  6. M13 Bacteriophage-Based Self-Assembly Structures and Their Functional Capabilities.

    PubMed

    Moon, Jong-Sik; Kim, Won-Geun; Kim, Chuntae; Park, Geun-Tae; Heo, Jeong; Yoo, So Y; Oh, Jin-Woo

    2015-06-01

    Controlling the assembly of basic structural building blocks in a systematic and orderly fashion is an emerging issue in various areas of science and engineering such as physics, chemistry, material science, biological engineering, and electrical engineering. The self-assembly technique, among many other kinds of ordering techniques, has several unique advantages and the M13 bacteriophage can be utilized as part of this technique. The M13 bacteriophage (Phage) can easily be modified genetically and chemically to demonstrate specific functions. This allows for its use as a template to determine the homogeneous distribution and percolated network structures of inorganic nanostructures under ambient conditions. Inexpensive and environmentally friendly synthesis can be achieved by using the M13 bacteriophage as a novel functional building block. Here, we discuss recent advances in the application of M13 bacteriophage self-assembly structures and the future of this technology.

  7. M13 Bacteriophage-Based Self-Assembly Structures and Their Functional Capabilities

    PubMed Central

    Moon, Jong-Sik; Kim, Won-Geun; Kim, Chuntae; Park, Geun-Tae; Heo, Jeong; Yoo, So Y; Oh, Jin-Woo

    2015-01-01

    Controlling the assembly of basic structural building blocks in a systematic and orderly fashion is an emerging issue in various areas of science and engineering such as physics, chemistry, material science, biological engineering, and electrical engineering. The self-assembly technique, among many other kinds of ordering techniques, has several unique advantages and the M13 bacteriophage can be utilized as part of this technique. The M13 bacteriophage (Phage) can easily be modified genetically and chemically to demonstrate specific functions. This allows for its use as a template to determine the homogeneous distribution and percolated network structures of inorganic nanostructures under ambient conditions. Inexpensive and environmentally friendly synthesis can be achieved by using the M13 bacteriophage as a novel functional building block. Here, we discuss recent advances in the application of M13 bacteriophage self-assembly structures and the future of this technology. PMID:26146494

  8. Solar collector-skylight assembly

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dame, R.E.

    1984-10-09

    A solar collector-skylight assembly having movable parabolic concentrators wherein, in one position the parabolic concentrators direct solar energy to a collector to heat fluid circulating therethrough to thereby provide a solar heater; and when the concentrators are moved to another position, the assembly functions as a skylight wherein the solar energy is allowed to pass through the collector, to thereby illuminate the interior of a building upon which the solar collector-skylight assembly is mounted.

  9. Design, Development and Testing of the GMI Reflector Deployment Assembly

    NASA Technical Reports Server (NTRS)

    Guy, Larry; Foster, Mike; McEachen, Mike; Pellicciotti, Joseph; Kubitschek, Michael

    2011-01-01

    The GMI Reflector Deployment Assembly (RDA) is an articulating structure that accurately positions and supports the main reflector of the Global Microwave Imager (GMI) throughout the 3 year mission life. The GMI instrument will fly on the core Global Precipitation Measurement (GPM) spacecraft and will be used to make calibrated radiometric measurements at multiple microwave frequencies and polarizations. The GPM mission is an international effort managed by the National Aeronautics and Space Administration (NASA) to improve climate, weather, and hydrometeorological predictions through more accurate and frequent precipitation measurements1. Ball Aerospace and Technologies Corporation (BATC) was selected by NASA Goddard to design, build, and test the GMI instrument. The RDA was designed and manufactured by ATK Aerospace Systems Group to meet a number of challenging packaging and performance requirements. ATK developed a flight-like engineering development unit (EDU) and two flight mechanisms that have been delivered to BATC. This paper will focus on driving GMI instrument system requirements, the RDA design, development, and test activities performed to demonstrate that requirements have been met.

  10. KSC-02pd0590

    NASA Image and Video Library

    2002-04-29

    KENNEDY SPACE CENTER, FLA. -- Space Shuttle Endeavour rests on Launch Pad 39A after rollout from the Vehicle Assembly Building. The Shuttle comprises the orbiter, in front, and the taller orange external tank behind it flanked by twin solid rocket boosters. The Shuttle sits on the Mobile Launcher Platform that straddles the flame trench below. On either side of Endeavour's tail and main engines are the tail service masts that support the fluid,, gas and electrical requirements of the orbiter's liquid oxyen and liquid hydrogen aft T-0 umbilicals. At left is the open Rotating Service Structure and the Fixed Service Structure to its right, with its 80-foot lightning mast on top. Mission STS-111 is designated UF-2, the 14th assembly flight to the International Space Station. Endeavour's payload includes the Multi-Purpose Logistics Module Leonardo and Mobile Base System. The mission also will swap resident crews on the Station, carrying the Expedition 5 crew and returning to Earth Expedition 4. Liftoff of Endeavour is scheduled between 4 and 8 p.m. May 30, 2002

  11. Measure Guideline. Incorporating Thick Layers of Exterior Rigid Insulation on Walls

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lstiburek, Joseph; Baker, Peter

    This measure guideline, written by the U.S. Department of Energy’s Building America team Building Science Corporation, provides information about the design and construction of wall assemblies that use layers of rigid exterior insulation thicker than 1-½ in. and that require a secondary cladding attachment location exterior to the insulation. The guideline is separated into several distinct sections that cover: (1) fundamental building science principles relating to the use of exterior insulation on wall assemblies; (2) design principles for tailoring this use to the specific project goals and requirements; and (3) construction detailing to increase understanding about implementing the various designmore » elements.« less

  12. Single molecule magnets from magnetic building blocks

    NASA Astrophysics Data System (ADS)

    Kroener, W.; Paretzki, A.; Cervetti, C.; Hohloch, S.; Rauschenbach, S.; Kern, K.; Dressel, M.; Bogani, L.; M&üLler, P.

    2013-03-01

    We provide a basic set of magnetic building blocks that can be rationally assembled, similar to magnetic LEGO bricks, in order to create a huge variety of magnetic behavior. Using rare-earth centers and multipyridine ligands, fine-tuning of intra and intermolecular exchange interaction is demonstrated. We have investigated a series of molecules with monomeric, dimeric and trimeric lanthanide centers using SQUID susceptometry and Hall bar magnetometry. A home-made micro-Hall-probe magnetometer was used to measure magnetic hysteresis loops at mK temperatures and fields up to 17 T. All compounds show hysteresis below blocking temperatures of 3 to 4 K. The correlation of the assembly of the building blocks with the magnetic properties will be discussed.

  13. Elasticity-dependent fast underwater adhesion demonstrated by macroscopic supramolecular assembly.

    PubMed

    Ju, Guannan; Cheng, Mengjiao; Guo, Fengli; Zhang, Qian; Shi, Feng

    2018-05-30

    Macroscopic supramolecular assembly (MSA) is a recent progress in supramolecular chemistry to associate visible building blocks through non-covalent interactions in a multivalent manner. Although various substrates (e. g. hydrogels, rigid materials) have been used, a general design rule of building blocks in MSA systems and interpretation of the assembly mechanism are still lacking and urgently in demand. Here we design three model systems with varied modulus and correlated the MSA probability with the elasticity. Based on the effects of substrate deformability on multivalency, we have proposed an elastic-modulus-dependent rule that building blocks below a critical modulus of 2.5 MPa can achieve MSA for the used host/guest system. Moreover, this MSA rule applies well to the design of materials applicable for fast underwater adhesion: Soft substrates (0.5 MPa) can achieve underwater adhesion within 10 s with one magnitude higher strength than that of rigid substrates (2.5 MPa). © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. KSC-98pc783

    NASA Image and Video Library

    1998-07-06

    KSC Center Director Roy D. Bridges Jr. and U.S. Congressman Dave Weldon (holding scissors) cut the ribbon at a ceremony on July 6 to open KSC's new 34,600-square-foot Space Shuttle Main Engine Processing Facility (SSMEPF). Joining in the ribbon cutting are (left) Ed Adamek, vice president and associate program manager for Ground Operations of United Space Alliance; Marvin L. Jones, director of Installation Operations; Donald R. McMonagle, manager of Launch Integration; (right) Wade Ivey of Ivey Construction, Inc.; Robert B. Sieck, director of Shuttle Processing; and John Plowden, vice president of Rocketdyne. A major addition to the existing Orbiter Processing Facility Bay 3, the SSMEPF replaces the Shuttle Main Engine Shop located in the Vehicle Assembly Building (VAB). The decision to move the shop out of the VAB was prompted by safety considerations and recent engine processing improvements. The first three main engines to be processed in the new facility will fly on Shuttle Endeavour's STS-88 mission in December 1998

  15. The SSMEPF opens with a ribbon-cutting ceremony

    NASA Technical Reports Server (NTRS)

    1998-01-01

    KSC Center Director Roy D. Bridges Jr. and U.S. Congressman Dave Weldon (holding scissors) cut the ribbon at a ceremony on July 6 to open KSC's new 34,600-square-foot Space Shuttle Main Engine Processing Facility (SSMEPF). Joining in the ribbon cutting are (left) Ed Adamek, vice president and associate program manager for Ground Operations of United Space Alliance; Marvin L. Jones, director of Installation Operations; Donald R. McMonagle, manager of Launch Integration; (right) Wade Ivey of Ivey Construction, Inc.; Robert B. Sieck, director of Shuttle Processing; and John Plowden, vice president of Rocketdyne. A major addition to the existing Orbiter Processing Facility Bay 3, the SSMEPF replaces the Shuttle Main Engine Shop located in the Vehicle Assembly Building (VAB). The decision to move the shop out of the VAB was prompted by safety considerations and recent engine processing improvements. The first three main engines to be processed in the new facility will fly on Shuttle Endeavour's STS-88 mission in December 1998.

  16. Technology Solutions Case Study: Cladding Attachment Over Thick Exterior Insulating Sheathing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    The addition of insulation to the exterior of buildings is an effective means of increasing the thermal resistance of wood-framed walls and mass masonry wall assemblies. Insulation on the exterior of the structure has many direct benefits, including better effective R-value from reduced thermal bridging, better condensation resistance, reduced thermal stress on the structure, as well as other commonly associated improvements such as increased airtightness and improved water management. Although the approach has proven effective, there is resistance to its widespread implementation due to a lack of research and understanding of the mechanisms involved in the development of the verticalmore » displacement resistance capacity. In addition, the long-term in-service performance of the system has been questioned due to potential creep effects of the assembly under the sustained dead load of the cladding and effects of varying environmental conditions. In addition, the current International Building Code (IBC) and International Residential Code (IRC) do not have a provision that specifically allows this assembly. In this project, researchers from Building Science Corporation, a Building America team, investigated these issues to better understand the mechanics behind this method of cladding attachment« less

  17. 2. NORTH AND WEST SIDES OF BUILDING 1601/1606/1607, WITH DISCHARGED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. NORTH AND WEST SIDES OF BUILDING 1601/1606/1607, WITH DISCHARGED TON CONTAINERS IN FOREGROUND. VIEW TO SOUTH. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  18. 1. WEST AND NORTH SIDES OF BUILDING 1601/1606/1607, WITH DISCHARGED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. WEST AND NORTH SIDES OF BUILDING 1601/1606/1607, WITH DISCHARGED TON CONTAINERS IN FOREGROUND. VIEW TO SOUTHEAST. - Rocky Mountain Arsenal, Cluster Bomb Assembly-Filling-Storage Building, 3500 feet South of Ninth Avenue; 2870 feet East of D Street, Commerce City, Adams County, CO

  19. Chapter 8: Fire Performance of Cross-Laminated Timber Assemblies (2012 US Edition)

    Treesearch

    Christian Dagenais; Robert H. White; Kuma Sumathipala

    2012-01-01

    Cross-laminated timber (CLT) is a promising wood-based structural component and has potential to provide cost-effective building solutions for residential, commercial and institutional buildings as well as large industrial facilities. Market acceptance of CLT requires that it meets the applicable building code requirements.

  20. Assembly of RNA nanostructures on supported lipid bilayers

    PubMed Central

    Dabkowska, Aleksandra P.; Michanek, Agnes; Jaeger, Luc; Rabe, Michael; Chworos, Arkadiusz; Höök, Fredrik; Nylander, Tommy; Sparr, Emma

    2014-01-01

    The assembly of nucleic acid nanostructures with controlled size and shape has large impact in the fields of nanotechnology, nanomedicine and synthetic biology. The directed arrangement of nanostructures at interfaces is important for many applications. In spite of this, the use of laterally mobile lipid bilayers to control RNA three-dimensional nanostructure formation on surfaces remains largely unexplored. Here, we direct the self-assembly of RNA building blocks into three-dimensional structures of RNA on fluid lipid bilayers composed of cationic 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) or mixtures of zwitterionic 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine (DOPC) and cationic sphingosine. We demonstrate the stepwise supramolecular assembly of discrete building blocks through specific and selective RNA-RNA interactions, based on results from quartz crystal microbalance with dissipation (QCM-D), ellipsometry, fluorescence recovery after photobleaching (FRAP) and total internal reflection fluorescence microscopy (TIRF) experiments. The assembly can be controlled to give a densely packed single layer of RNA polyhedrons at the fluid lipid bilayer surface. We show that assembly of the 3D structure can be modulated by sequence specific interactions, surface charge and changes in the salt composition and concentration. In addition, the tertiary structure of the RNA polyhedron can be controllably switched from an extended structure to one that is dense and compact. The versatile approach to building up three-dimensional structures of RNA does not require modification of the surface or the RNA molecules, and can be used as a bottom-up means of nanofabrication of functionalized bio-mimicking surfaces. PMID:25417592

  1. Influence of Geometries on the Assembly of Snowman-Shaped Janus Nanoparticles.

    PubMed

    Kang, Chengjun; Honciuc, Andrei

    2018-04-24

    The self-assembly of micro/nanoparticles into suprastructures is a promising way to develop reconfigurable materials and to gain insights into the fundamental question of how matter organizes itself. The geometry of particles, especially those deviating from perfectly spherical shapes, is of significant importance in colloidal assembly because it influences the particle "recognition", determines the particle packing, and ultimately dictates the formation of assembled suprastructures. In order to organize particles into desired structures, it is of vital importance to understand the relationship between the shape of the colloidal building blocks and the assembled suprastructures. This fundamental issue is an enduring topic in the assembly of molecular surfactants, but it remained elusive in colloidal assembly. To address this issue, we use snowman-shaped Janus nanoparticles (JNPs) as a model to systematically study the effect of colloidal geometries on their assembled suprastructures. Ten types of JNPs with identical chemical compositions but with different geometries were synthesized. Specifically, the synthesized JNPs differ in their lobe size ratios, phase separation degrees, and overall sizes. We show that by altering these parameters, both finite suprastructures, such as capsules with different curvatures, and nonfinite suprastructures, including free-standing single-layered or double-layered JNPs sheets, can be obtained via self-assembly. All these different types of suprastructures are constituted by highly oriented and hexagonally packed JNPs. These findings demonstrate the significance of geometries in colloidal assembly, such that slightly changing the building block geometries could result in a large variety of very different assembled structures, without altering the chemistry of the particles.

  2. 40. Exterior view of dockage, marine railway #4, and assembly ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    40. Exterior view of dockage, marine railway #4, and assembly building. Note BBW Tug Sam on railway and BBW-Built Stardust (#1) at end of dock. - Barbour Boat Works, Tryon Palace Drive, New Bern, Craven County, NC

  3. 124. JOB NO. 1347A, SHEET 6, 1927, POWER HOUSE; FORD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    124. JOB NO. 1347-A, SHEET 6, 1927, POWER HOUSE; FORD MOTOR COMPANY; SECTION BB AND DETAILS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  4. 4. VIEW TO EAST SHOWING WEST END OF CRANEWAY (CENTER), ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. VIEW TO EAST SHOWING WEST END OF CRANEWAY (CENTER), WEST SIDE OF ASSEMBLY BUILDING (LEFT), AND WHARF (RIGHT). - Rosie the Riveter National Historical Park, Ford Assembly Plant, 1400 Harbour Way South, Richmond, Contra Costa County, CA

  5. KSC-2010-4892

    NASA Image and Video Library

    2010-09-28

    CAPE CANAVERAL, Fla. -- The Space Shuttle Program's last external fuel tank, ET-122, moves from the Turn Basin to the Vehicle Assembly Building at NASA's Kennedy Space Center in Florida. The tank traveled 900 miles by sea from NASA's Michoud Assembly Facility in New Orleans aboard the Pegasus Barge. Once inside the Vehicle Assembly Building, it eventually will be attached to space shuttle Endeavour for the STS-134 mission to the International Space Station. STS-134, targeted to launch in Feb. 2011, currently is scheduled to be the last mission in the shuttle program. The tank, which is the largest element of the space shuttle stack, was damaged during Hurricane Katrina in August 2005 and restored to flight configuration by Lockheed Martin Space Systems Company employees. Photo credit: NASA/Jack Pfaller

  6. KSC-2010-4891

    NASA Image and Video Library

    2010-09-28

    CAPE CANAVERAL, Fla. -- The Space Shuttle Program's last external fuel tank, ET-122, moves from the Turn Basin to the Vehicle Assembly Building at NASA's Kennedy Space Center in Florida. The tank traveled 900 miles by sea from NASA's Michoud Assembly Facility in New Orleans aboard the Pegasus Barge. Once inside the Vehicle Assembly Building, it eventually will be attached to space shuttle Endeavour for the STS-134 mission to the International Space Station. STS-134, targeted to launch in Feb. 2011, currently is scheduled to be the last mission in the shuttle program. The tank, which is the largest element of the space shuttle stack, was damaged during Hurricane Katrina in August 2005 and restored to flight configuration by Lockheed Martin Space Systems Company employees. Photo credit: NASA/Jack Pfaller

  7. KSC-2010-4890

    NASA Image and Video Library

    2010-09-28

    CAPE CANAVERAL, Fla. -- The Space Shuttle Program's last external fuel tank, ET-122, moves from the Turn Basin to the Vehicle Assembly Building at NASA's Kennedy Space Center in Florida. The tank traveled 900 miles by sea from NASA's Michoud Assembly Facility in New Orleans aboard the Pegasus Barge. Once inside the Vehicle Assembly Building, it eventually will be attached to space shuttle Endeavour for the STS-134 mission to the International Space Station. STS-134, targeted to launch in Feb. 2011, currently is scheduled to be the last mission in the shuttle program. The tank, which is the largest element of the space shuttle stack, was damaged during Hurricane Katrina in August 2005 and restored to flight configuration by Lockheed Martin Space Systems Company employees. Photo credit: NASA/Jack Pfaller

  8. 2. VIEW LOOKING NORTHEAST AT BUILDING 444 UNDER CONSTRUCTION. BUILDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. VIEW LOOKING NORTHEAST AT BUILDING 444 UNDER CONSTRUCTION. BUILDING 444 WAS THE PRIMARY NON-PLUTONIUM MANUFACTURING FACILITY AT THE ROCKY FLATS PLANT. MANUFACTURING PROCESSES COMPLETED IN THIS BUILDING WERE USED TO FABRICATE WEAPONS COMPONENTS AND ASSEMBLIES FOR A VARIETY OF MATERIALS, INCLUDING DEPLETED URANIUM, BERYLLIUM, STAINLESS STEEL, ALUMINUM, AND VANADIUM. (4/25/52) - Rocky Flats Plant, Non-Nuclear Production Facility, South of Cottonwood Avenue, west of Seventh Avenue & east of Building 460, Golden, Jefferson County, CO

  9. Selective self-assembly of adenine-silver nanoparticles forms rings resembling the size of cells

    PubMed Central

    Choi, Sungmoon; Park, Soonyoung; Yang, Seon-Ah; Jeong, Yujin; Yu, Junhua

    2015-01-01

    Self-assembly has played critical roles in the construction of functional nanomaterials. However, the structure of the macroscale multicomponent materials built by the self-assembly of nanoscale building blocks is hard to predict due to multiple intermolecular interactions of great complexity. Evaporation of solvents is usually an important approach to induce kinetically stable assemblies of building blocks with a large-scale specific arrangement. During such a deweting process, we tried to monitor the possible interactions between silver nanoparticles and nucleobases at a larger scale by epifluorescence microscopy, thanks to the doping of silver nanoparticles with luminescent silver nanodots. ssDNA oligomer-stabilized silver nanoparticles and adenine self-assemble to form ring-like compartments similar to the size of modern cells. However, the silver ions only dismantle the self-assembly of adenine. The rings are thermodynamically stable as the drying process only enrich the nanoparticles-nucleobase mixture to a concentration that activates the self-assembly. The permeable membrane-like edge of the ring is composed of adenine filaments glued together by silver nanoparticles. Interestingly, chemicals are partially confined and accumulated inside the ring, suggesting that this might be used as a microreactor to speed up chemical reactions during a dewetting process. PMID:26643504

  10. Peripheral infrastructure vectors and an extended set of plant parts for the Modular Cloning system

    PubMed Central

    Kretschmer, Carola; Gruetzner, Ramona; Löfke, Christian; Dagdas, Yasin; Bürstenbinder, Katharina; Marillonnet, Sylvestre

    2018-01-01

    Standardized DNA assembly strategies facilitate the generation of multigene constructs from collections of building blocks in plant synthetic biology. A common syntax for hierarchical DNA assembly following the Golden Gate principle employing Type IIs restriction endonucleases was recently developed, and underlies the Modular Cloning and GoldenBraid systems. In these systems, transcriptional units and/or multigene constructs are assembled from libraries of standardized building blocks, also referred to as phytobricks, in several hierarchical levels and by iterative Golden Gate reactions. Here, a toolkit containing further modules for the novel DNA assembly standards was developed. Intended for use with Modular Cloning, most modules are also compatible with GoldenBraid. Firstly, a collection of approximately 80 additional phytobricks is provided, comprising e.g. modules for inducible expression systems, promoters or epitope tags. Furthermore, DNA modules were developed for connecting Modular Cloning and Gateway cloning, either for toggling between systems or for standardized Gateway destination vector assembly. Finally, first instances of a “peripheral infrastructure” around Modular Cloning are presented: While available toolkits are designed for the assembly of plant transformation constructs, vectors were created to also use coding sequence-containing phytobricks directly in yeast two hybrid interaction or bacterial infection assays. The presented material will further enhance versatility of hierarchical DNA assembly strategies. PMID:29847550

  11. Terminating DNA Tile Assembly with Nanostructured Caps.

    PubMed

    Agrawal, Deepak K; Jiang, Ruoyu; Reinhart, Seth; Mohammed, Abdul M; Jorgenson, Tyler D; Schulman, Rebecca

    2017-10-24

    Precise control over the nucleation, growth, and termination of self-assembly processes is a fundamental tool for controlling product yield and assembly dynamics. Mechanisms for altering these processes programmatically could allow the use of simple components to self-assemble complex final products or to design processes allowing for dynamic assembly or reconfiguration. Here we use DNA tile self-assembly to develop general design principles for building complexes that can bind to a growing biomolecular assembly and terminate its growth by systematically characterizing how different DNA origami nanostructures interact with the growing ends of DNA tile nanotubes. We find that nanostructures that present binding interfaces for all of the binding sites on a growing facet can bind selectively to growing ends and stop growth when these interfaces are presented on either a rigid or floppy scaffold. In contrast, nucleation of nanotubes requires the presentation of binding sites in an arrangement that matches the shape of the structure's facet. As a result, it is possible to build nanostructures that can terminate the growth of existing nanotubes but cannot nucleate a new structure. The resulting design principles for constructing structures that direct nucleation and termination of the growth of one-dimensional nanostructures can also serve as a starting point for programmatically directing two- and three-dimensional crystallization processes using nanostructure design.

  12. PV/thermal solar power assembly

    DOEpatents

    Ansley, Jeffrey H.; Botkin, Jonathan D.; Dinwoodie, Thomas L.

    2004-01-13

    A flexible solar power assembly (2) includes a flexible photovoltaic device (16) attached to a flexible thermal solar collector (4). The solar power assembly can be rolled up for transport and then unrolled for installation on a surface, such as the roof (20, 25) or side wall of a building or other structure, by use of adhesive and/or other types of fasteners (23).

  13. KSC-2010-4888

    NASA Image and Video Library

    2010-09-28

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, Canadian Space Agency astronaut Chris Hadfield address the attendees at a ceremony being held to commemorate the move from Kennedy's Assembly Refurbishment Facility (ARF) to the Vehicle Assembly Building (VAB) of the Space Shuttle Program's final solid rocket booster structural assembly -- the right-hand forward. The move was postponed because of inclement weather. Photo credit: NASA/Kim Shiflett

  14. KSC-2010-4886

    NASA Image and Video Library

    2010-09-28

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, Roger Elliot with United Space Alliance addresses the attendees at a ceremony being held to commemorate the move from Kennedy's Assembly Refurbishment Facility (ARF) to the Vehicle Assembly Building (VAB) of the Space Shuttle Program's final solid rocket booster structural assembly -- the right-hand forward. The move was postponed because of inclement weather. Photo credit: NASA/Kim Shiflett

  15. KSC-2010-4887

    NASA Image and Video Library

    2010-09-28

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, Center Director Bob Cabana speaks to the attendees at a ceremony being held to commemorate the move from Kennedy's Assembly Refurbishment Facility (ARF) to the Vehicle Assembly Building (VAB) of the Space Shuttle Program's final solid rocket booster structural assembly -- the right-hand forward. The move was postponed because of inclement weather. Photo credit: NASA/Kim Shiflett

  16. 16. VIEW TO NORTHEAST OF SECONDFLOOR ASSEMBLY AREA FROM NEAR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. VIEW TO NORTHEAST OF SECOND-FLOOR ASSEMBLY AREA FROM NEAR SOUTHWEST WEST. NOTE DIFFERENCE IN ROOF STRUCTURE BETWEEN SAWTOOTH SKYLIGHTS OVER MOST OF THE SECOND FLOOR (RIGHT) AND THE PORTION OF THE ROOF RUNNING ALONG THE WEST EDGE OF THE BUILDING (LEFT). - Rosie the Riveter National Historical Park, Ford Assembly Plant, 1400 Harbour Way South, Richmond, Contra Costa County, CA

  17. GoldenBraid: An Iterative Cloning System for Standardized Assembly of Reusable Genetic Modules

    PubMed Central

    Sarrion-Perdigones, Alejandro; Falconi, Erica Elvira; Zandalinas, Sara I.; Juárez, Paloma; Fernández-del-Carmen, Asun; Granell, Antonio; Orzaez, Diego

    2011-01-01

    Synthetic Biology requires efficient and versatile DNA assembly systems to facilitate the building of new genetic modules/pathways from basic DNA parts in a standardized way. Here we present GoldenBraid (GB), a standardized assembly system based on type IIS restriction enzymes that allows the indefinite growth of reusable gene modules made of standardized DNA pieces. The GB system consists of a set of four destination plasmids (pDGBs) designed to incorporate multipartite assemblies made of standard DNA parts and to combine them binarily to build increasingly complex multigene constructs. The relative position of type IIS restriction sites inside pDGB vectors introduces a double loop (“braid”) topology in the cloning strategy that allows the indefinite growth of composite parts through the succession of iterative assembling steps, while the overall simplicity of the system is maintained. We propose the use of GoldenBraid as an assembly standard for Plant Synthetic Biology. For this purpose we have GB-adapted a set of binary plasmids for A. tumefaciens-mediated plant transformation. Fast GB-engineering of several multigene T-DNAs, including two alternative modules made of five reusable devices each, and comprising a total of 19 basic parts are also described. PMID:21750718

  18. GoldenBraid: an iterative cloning system for standardized assembly of reusable genetic modules.

    PubMed

    Sarrion-Perdigones, Alejandro; Falconi, Erica Elvira; Zandalinas, Sara I; Juárez, Paloma; Fernández-del-Carmen, Asun; Granell, Antonio; Orzaez, Diego

    2011-01-01

    Synthetic Biology requires efficient and versatile DNA assembly systems to facilitate the building of new genetic modules/pathways from basic DNA parts in a standardized way. Here we present GoldenBraid (GB), a standardized assembly system based on type IIS restriction enzymes that allows the indefinite growth of reusable gene modules made of standardized DNA pieces. The GB system consists of a set of four destination plasmids (pDGBs) designed to incorporate multipartite assemblies made of standard DNA parts and to combine them binarily to build increasingly complex multigene constructs. The relative position of type IIS restriction sites inside pDGB vectors introduces a double loop ("braid") topology in the cloning strategy that allows the indefinite growth of composite parts through the succession of iterative assembling steps, while the overall simplicity of the system is maintained. We propose the use of GoldenBraid as an assembly standard for Plant Synthetic Biology. For this purpose we have GB-adapted a set of binary plasmids for A. tumefaciens-mediated plant transformation. Fast GB-engineering of several multigene T-DNAs, including two alternative modules made of five reusable devices each, and comprising a total of 19 basic parts are also described.

  19. Self-assembled bionanostructures: proteins following the lead of DNA nanostructures

    PubMed Central

    2014-01-01

    Natural polymers are able to self-assemble into versatile nanostructures based on the information encoded into their primary structure. The structural richness of biopolymer-based nanostructures depends on the information content of building blocks and the available biological machinery to assemble and decode polymers with a defined sequence. Natural polypeptides comprise 20 amino acids with very different properties in comparison to only 4 structurally similar nucleotides, building elements of nucleic acids. Nevertheless the ease of synthesizing polynucleotides with selected sequence and the ability to encode the nanostructural assembly based on the two specific nucleotide pairs underlay the development of techniques to self-assemble almost any selected three-dimensional nanostructure from polynucleotides. Despite more complex design rules, peptides were successfully used to assemble symmetric nanostructures, such as fibrils and spheres. While earlier designed protein-based nanostructures used linked natural oligomerizing domains, recent design of new oligomerizing interaction surfaces and introduction of the platform for topologically designed protein fold may enable polypeptide-based design to follow the track of DNA nanostructures. The advantages of protein-based nanostructures, such as the functional versatility and cost effective and sustainable production methods provide strong incentive for further development in this direction. PMID:24491139

  20. A new building block for DNA network formation by self-assembly and polymerase chain reaction.

    PubMed

    Bußkamp, Holger; Keller, Sascha; Robotta, Marta; Drescher, Malte; Marx, Andreas

    2014-01-01

    The predictability of DNA self-assembly is exploited in many nanotechnological approaches. Inspired by naturally existing self-assembled DNA architectures, branched DNA has been developed that allows self-assembly to predesigned architectures with dimensions on the nanometer scale. DNA is an attractive material for generation of nanostructures due to a plethora of enzymes which modify DNA with high accuracy, providing a toolbox for many different manipulations to construct nanometer scaled objects. We present a straightforward synthesis of a rigid DNA branching building block successfully used for the generation of DNA networks by self-assembly and network formation by enzymatic DNA synthesis. The Y-shaped 3-armed DNA construct, bearing 3 primer strands is accepted by Taq DNA polymerase. The enzyme uses each arm as primer strand and incorporates the branched construct into large assemblies during PCR. The networks were investigated by agarose gel electrophoresis, atomic force microscopy, dynamic light scattering, and electron paramagnetic resonance spectroscopy. The findings indicate that rather rigid DNA networks were formed. This presents a new bottom-up approach for DNA material formation and might find applications like in the generation of functional hydrogels.

  1. Kinetically controlled transition from disordered aggregates to ordered lattices of a computationally designed peptide sequence.

    NASA Astrophysics Data System (ADS)

    Tian, Yu; Zhang, Huixi; Kiick, Kristi; Saven, Jeffrey; Pochan, Darrin

    Peptides with well-defined secondary-structures have the ability to exhibit specific, local shapes, which enables the design of complex nanostructures through intermolecular assembly. Our computationally designed coiled-coil homotetrameric peptide building block can self-assemble into 2-D nanomaterial lattices with predetermined symmetries by control of the coiled-coil bundle exterior amino acid residues. And the assemblies can be controlled kinetically. Firstly, the solution pH influences the assembly by affecting the external charged state of peptide bundles which can lead the bundles to be either repulsive or attractive to each other. At room temperature when peptides are under the least charged pH conditions, disordered aggregates are formed that slowly transformed into the desired 2-D lattice structures over long periods of time (weeks). Around neutral pH, even subtle charge differences that come from small pH changes can have an influence on the thickness of afterwards formed plates. Secondly, the solution temperature can largely eliminate the formation of disordered aggregates and accelerate the assembling of matured, desired nanomaterial plates by providing extra energy for the organization process of assembly building blocks. The ability to control the assembly process kinetically makes our peptide plate assemblies very promising templates for further applications to develop inorganic-organic hybrid materials. Funding acknowledged from NSF DMREF program under awards DMR-1234161 and DMR-1235084.

  2. Electrophoretic build-up of alternately multilayered films and micropatterns based on graphene sheets and nanoparticles and their applications in flexible supercapacitors.

    PubMed

    Niu, Zhiqiang; Du, Jianjun; Cao, Xuebo; Sun, Yinghui; Zhou, Weiya; Hng, Huey Hoon; Ma, Jan; Chen, Xiaodong; Xie, Sishen

    2012-10-22

    Graphene nanosheets and metal nanoparticles (NPs) have been used as nano-building-blocks for assembly into macroscale hybrid structures with promising performance in electrical devices. However, in most graphene and metal NP hybrid structures, the graphene sheets and metal NPs (e.g., AuNPs) do not enable control of the reaction process, orientation of building blocks, and organization at the nanoscale. Here, an electrophoretic layer-by-layer assembly for constructing multilayered reduced graphene oxide (RGO)/AuNP films and lateral micropatterns is presented. This assembly method allows easy control of the nano-architecture of building blocks along the normal direction of the film, including the number and thickness of RGO and AuNP layers, in addition to control of the lateral orientation of the resultant multilayered structures. Conductivity of multilayered RGO/AuNP hybrid nano-architecture shows great improvement caused by a bridging effect of the AuNPs along the out-of-plane direction between the upper and lower RGO layers. The results clearly show the potential of electrophoretic build-up in the fabrication of graphene-based alternately multilayered films and patterns. Finally, flexible supercapacitors based on multilayered RGO/AuNP hybrid films are fabricated, and excellent performance, such as high energy and power densities, are achieved. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. 72. SECOND FLOOR, HEATER ROOM ENTRANCE (UPPER RIGHT) AND STEEL, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    72. SECOND FLOOR, HEATER ROOM ENTRANCE (UPPER RIGHT) AND STEEL, CONCRETE, BRICK, AND SPRING AIR CONDITIONER BASE, BAY 31-32/4 SOUTH, TO WEST - Ford Motor Company Edgewater Assembly Plant, Assembly Building, 309 River Road, Edgewater, Bergen County, NJ

  4. 123. JOB NO. 1347A, SHEET 4, 1927, POWER HOUSE; FORD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    123. JOB NO. 1347-A, SHEET 4, 1927, POWER HOUSE; FORD MOTOR COMPANY; NORTH, SOUTH, EAST, AND WEST ELEVATIONS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  5. 121. JOB NO. 1347E, SHEET 7S, 1929, DOCK DESIGN FOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    121. JOB NO. 1347-E, SHEET 7S, 1929, DOCK DESIGN FOR FORD MOTOR COMPANY; SECTIONS AND DETAILS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  6. 122. JOB NO. 1347E, SHEET 3S, 1927, DOCK; FORD MOTOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    122. JOB NO. 1347-E, SHEET 3S, 1927, DOCK; FORD MOTOR COMPANY; DECK PLAN OF DOCK - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  7. Self-assembly of multi-stranded RNA motifs into lattices and tubular structures

    PubMed Central

    Stewart, Jaimie Marie; Subramanian, Hari K. K.

    2017-01-01

    Abstract Rational design of nucleic acid molecules yields self-assembling scaffolds with increasing complexity, size and functionality. It is an open question whether design methods tailored to build DNA nanostructures can be adapted to build RNA nanostructures with comparable features. Here we demonstrate the formation of RNA lattices and tubular assemblies from double crossover (DX) tiles, a canonical motif in DNA nanotechnology. Tubular structures can exceed 1 μm in length, suggesting that this DX motif can produce very robust lattices. Some of these tubes spontaneously form with left-handed chirality. We obtain assemblies by using two methods: a protocol where gel-extracted RNA strands are slowly annealed, and a one-pot transcription and anneal procedure. We identify the tile nick position as a structural requirement for lattice formation. Our results demonstrate that stable RNA structures can be obtained with design tools imported from DNA nanotechnology. These large assemblies could be potentially integrated with a variety of functional RNA motifs for drug or nanoparticle delivery, or for colocalization of cellular components. PMID:28204562

  8. HOT CELL BUILDING, TRA632. CONTEXTUAL VIEW ALONG WALLEYE AVENUE, CAMERA ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    HOT CELL BUILDING, TRA-632. CONTEXTUAL VIEW ALONG WALLEYE AVENUE, CAMERA FACING EASTERLY. HOT CELL BUILDING IS AT CENTER LEFT OF VIEW; THE LOW-BAY PROJECTION WITH LADDER IS THE TEST TRAIN ASSEMBLY FACILITY, ADDED IN 1968. MTR BUILDING IS IN LEFT OF VIEW. HIGH-BAY BUILDING AT RIGHT IS THE ENGINEERING TEST REACTOR BUILDING, TRA-642. INL NEGATIVE NO. HD46-32-1. Mike Crane, Photographer, 4/2005 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  9. GENERAL VIEW OF THE MARTIN BOMBER PLANT LOOKING SOUTHWEST FROM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL VIEW OF THE MARTIN BOMBER PLANT LOOKING SOUTHWEST FROM "HOSPITAL HILL" SHOWING FROM THE LEFT THE METAL & PAPER SALVAGE BUILDING, AIRCRAFT MANUFACTURING AND ASSEMBLY BUILDING, BOILER HOUSE, OIL HOUSE, AND ADMINISTRATION BUILDLING. - Offutt Air Force Base, Glenn L. Martin-Nebraska Bomber Plant, Building D, Peacekeeper Drive, Bellevue, Sarpy County, NE

  10. 36. Historic photo of Building 202 interior, shows shop area ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    36. Historic photo of Building 202 interior, shows shop area with engineers assembling twenty-thousand-pound-thrust rocket engine, December 15, 1958. On file at NASA Plumbrook Research Center, Sandusky, Ohio. NASA photo number C-49343. - Rocket Engine Testing Facility, GRC Building No. 202, NASA Glenn Research Center, Cleveland, Cuyahoga County, OH

  11. 24 CFR 200.949 - Building product standards and certification program for exterior insulated steel door systems.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Mass Applications; (ii) ISDSI-100-90—Door Size Dimensional Standard and Assembly Tolerances for... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Building product standards and... INTRODUCTION TO FHA PROGRAMS Minimum Property Standards § 200.949 Building product standards and certification...

  12. Sensor mount assemblies and sensor assemblies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miller, David H

    2012-04-10

    Sensor mount assemblies and sensor assemblies are provided. In an embodiment, by way of example only, a sensor mount assembly includes a busbar, a main body, a backing surface, and a first finger. The busbar has a first end and a second end. The main body is overmolded onto the busbar. The backing surface extends radially outwardly relative to the main body. The first finger extends axially from the backing surface, and the first finger has a first end, a second end, and a tooth. The first end of the first finger is disposed on the backing surface, and themore » tooth is formed on the second end of the first finger.« less

  13. Pore configuration landscape of granular crystallization.

    PubMed

    Saadatfar, M; Takeuchi, H; Robins, V; Francois, N; Hiraoka, Y

    2017-05-12

    Uncovering grain-scale mechanisms that underlie the disorder-order transition in assemblies of dissipative, athermal particles is a fundamental problem with technological relevance. To date, the study of granular crystallization has mainly focussed on the symmetry of crystalline patterns while their emergence and growth from irregular clusters of grains remains largely unexplored. Here crystallization of three-dimensional packings of frictional spheres is studied at the grain-scale using X-ray tomography and persistent homology. The latter produces a map of the topological configurations of grains within static partially crystallized packings. Using numerical simulations, we show that similar maps are measured dynamically during the melting of a perfect crystal. This map encodes new information on the formation process of tetrahedral and octahedral pores, the building blocks of perfect crystals. Four key formation mechanisms of these pores reproduce the main changes of the map during crystallization and provide continuous deformation pathways representative of the crystallization dynamics.

  14. Pore configuration landscape of granular crystallization

    PubMed Central

    Saadatfar, M.; Takeuchi, H.; Robins, V.; Francois, N.; Hiraoka, Y.

    2017-01-01

    Uncovering grain-scale mechanisms that underlie the disorder–order transition in assemblies of dissipative, athermal particles is a fundamental problem with technological relevance. To date, the study of granular crystallization has mainly focussed on the symmetry of crystalline patterns while their emergence and growth from irregular clusters of grains remains largely unexplored. Here crystallization of three-dimensional packings of frictional spheres is studied at the grain-scale using X-ray tomography and persistent homology. The latter produces a map of the topological configurations of grains within static partially crystallized packings. Using numerical simulations, we show that similar maps are measured dynamically during the melting of a perfect crystal. This map encodes new information on the formation process of tetrahedral and octahedral pores, the building blocks of perfect crystals. Four key formation mechanisms of these pores reproduce the main changes of the map during crystallization and provide continuous deformation pathways representative of the crystallization dynamics. PMID:28497794

  15. Pore configuration landscape of granular crystallization

    NASA Astrophysics Data System (ADS)

    Saadatfar, M.; Takeuchi, H.; Robins, V.; Francois, N.; Hiraoka, Y.

    2017-05-01

    Uncovering grain-scale mechanisms that underlie the disorder-order transition in assemblies of dissipative, athermal particles is a fundamental problem with technological relevance. To date, the study of granular crystallization has mainly focussed on the symmetry of crystalline patterns while their emergence and growth from irregular clusters of grains remains largely unexplored. Here crystallization of three-dimensional packings of frictional spheres is studied at the grain-scale using X-ray tomography and persistent homology. The latter produces a map of the topological configurations of grains within static partially crystallized packings. Using numerical simulations, we show that similar maps are measured dynamically during the melting of a perfect crystal. This map encodes new information on the formation process of tetrahedral and octahedral pores, the building blocks of perfect crystals. Four key formation mechanisms of these pores reproduce the main changes of the map during crystallization and provide continuous deformation pathways representative of the crystallization dynamics.

  16. KENNEDY SPACE CENTER, FLA. - In the Columbia Debris Hangar, Jack Nowling moves a box filled with part of the Columbia debris. About 83,000 pieces were shipped to KSC during search and recovery efforts in East Texas. An area of the Vehicle Assembly Building is being prepared to store the debris.

    NASA Image and Video Library

    2003-09-10

    KENNEDY SPACE CENTER, FLA. - In the Columbia Debris Hangar, Jack Nowling moves a box filled with part of the Columbia debris. About 83,000 pieces were shipped to KSC during search and recovery efforts in East Texas. An area of the Vehicle Assembly Building is being prepared to store the debris.

  17. KENNEDY SPACE CENTER, FLA. - Containers in the Columbia Debris Hangar are lined up after being emptied of the Columbia debris. The debris is being transferred to storage in the Vehicle Assembly Building. About 83,000 pieces were shipped to KSC during search and recovery efforts in East Texas.

    NASA Image and Video Library

    2003-09-02

    KENNEDY SPACE CENTER, FLA. - Containers in the Columbia Debris Hangar are lined up after being emptied of the Columbia debris. The debris is being transferred to storage in the Vehicle Assembly Building. About 83,000 pieces were shipped to KSC during search and recovery efforts in East Texas.

  18. KENNEDY SPACE CENTER, FLA. - A camera is installed on the aft skirt of a solid rocket booster in preparation for a vibration test of the Mobile Launcher Platform with SRBs and external tank mounted. The MLP will roll from one bay to another in the Vehicle Assembly Building.

    NASA Image and Video Library

    2003-11-06

    KENNEDY SPACE CENTER, FLA. - A camera is installed on the aft skirt of a solid rocket booster in preparation for a vibration test of the Mobile Launcher Platform with SRBs and external tank mounted. The MLP will roll from one bay to another in the Vehicle Assembly Building.

  19. Structural Polymorphism in a Self-Assembled Tri-Aromatic Peptide System.

    PubMed

    Brown, Noam; Lei, Jiangtao; Zhan, Chendi; Shimon, Linda J W; Adler-Abramovich, Lihi; Wei, Guanghong; Gazit, Ehud

    2018-04-24

    Self-assembly is a process of key importance in natural systems and in nanotechnology. Peptides are attractive building blocks due to their relative facile synthesis, biocompatibility, and other unique properties. Diphenylalanine (FF) and its derivatives are known to form nanostructures of various architectures and interesting and varied characteristics. The larger triphenylalanine peptide (FFF) was found to self-assemble as efficiently as FF, forming related but distinct architectures of plate-like and spherical nanostructures. Here, to understand the effect of triaromatic systems on the self-assembly process, we examined carboxybenzyl-protected diphenylalanine (z-FF) as a minimal model for such an arrangement. We explored different self-assembly conditions by changing solvent compositions and peptide concentrations, generating a phase diagram for the assemblies. We discovered that z-FF can form a variety of structures, including nanowires, fibers, nanospheres, and nanotoroids, the latter were previously observed only in considerably larger or co-assembly systems. Secondary structure analysis revealed that all assemblies possessed a β-sheet conformation. Additionally, in solvent combinations with high water ratios, z-FF formed rigid and self-healing hydrogels. X-ray crystallography revealed a "wishbone" structure, in which z-FF dimers are linked by hydrogen bonds mediated by methanol molecules, with a 2-fold screw symmetry along the c-axis. All-atom molecular dynamics (MD) simulations revealed conformations similar to the crystal structure. Coarse-grained MD simulated the assembly of the peptide into either fibers or spheres in different solvent systems, consistent with the experimental results. This work thus expands the building block library for the fabrication of nanostructures by peptide self-assembly.

  20. KSC-2014-4140

    NASA Image and Video Library

    2014-09-25

    CAPE CANAVERAL, Fla. – Coupled Florida East Coast Railway, or FEC, locomotives No. 433 and No. 428 pass the Vehicle Assembly Building in Launch Complex 39 at NASA’s Kennedy Space Center in Florida on their way to NASA's Locomotive Maintenance Facility. Kennedy's Center Planning and Development Directorate has enlisted the locomotives to support a Rail Vibration Test for the Canaveral Port Authority. The purpose of the test is to collect amplitude, frequency and vibration test data utilizing two Florida East Coast locomotives operating on KSC tracks to ensure that future railroad operations will not affect launch vehicle processing at the center. Buildings instrumented for the test include the Rotation Processing Surge Facility, Thermal Protection Systems Facility, Vehicle Assembly Building, Orbiter Processing Facility and Booster Fabrication Facility. Photo credit: NASA/Daniel Casper

  1. International Space Station: becoming a reality.

    PubMed

    David, L

    1999-07-01

    An overview of the development of the International Space Station (ISS) is presented starting with a brief history of space station concepts from the 1960's to the decision to build the present ISS. Other topics discussed include partnerships with Japan, Canada, ESA countries, and Russia; design changes to the ISS modules, the use of the ISS for scientific purposes and the application of space research to medicine on Earth; building ISS modules on Earth, international funding for Russian components, and the political aspects of including Russia in critical building plans. Sidebar articles examine commercialization of the ISS, multinational efforts in the design and building of the ISS, emergency transport to Earth, the use of robotics in ISS assembly, application of lessons learned from the Skylab project to the ISS, initial ISS assembly in May 1999, planned ISS science facilities, and an overview of space stations in science fiction.

  2. General view taken in the transfer aisle of the Vehicle ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view taken in the transfer aisle of the Vehicle Assembly Building at the Kennedy Space Center looking at the Orbiter Discovery hoisted, rotated to a vertical position and moving to an assembly bay to be mated to the External Tank/Solid Rocket Booster assembly. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  3. KSC-2010-4884

    NASA Image and Video Library

    2010-09-28

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, Canadian Space Agency astronaut Chris Hadfield (left) and NASA astronaut Gregory C. Johnson attend a ceremony being held to commemorate the move from Kennedy's Assembly Refurbishment Facility (ARF) to the Vehicle Assembly Building (VAB) of the Space Shuttle Program's final solid rocket booster structural assembly -- the right-hand forward. The move was postponed because of inclement weather. Photo credit: NASA/Kim Shiflett

  4. KSC-2010-4889

    NASA Image and Video Library

    2010-09-28

    CAPE CANAVERAL, Fla. -- At NASA's Kennedy Space Center in Florida, United Space Alliance employees gather and hold up a banner at a ceremony being held to commemorate the move from Kennedy's Assembly Refurbishment Facility (ARF) to the Vehicle Assembly Building (VAB) of the Space Shuttle Program's final solid rocket booster structural assembly -- the right-hand forward. The move was postponed because of inclement weather. Photo credit: NASA/Kim Shiflett

  5. Astronauts Jerry Ross and Sherwood Spring assemble ACCESS components

    NASA Image and Video Library

    1985-12-01

    61B-41-047 (1 Dec 1985) --- Astronauts Jerry L. Ross (left) and Sherwood C. (Woody) Spring are photographed by Astronaut Bryan D. O'Connor as they continue to assemble more pieces of the EASE (Experimental Assembly of Structures in Extravehicular Activities) device during the week-long STS 61-B mission. This frame is one of a series covering the structure's build-up.

  6. General view of the Aft Skirt Assembly and the Aft ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of the Aft Skirt Assembly and the Aft Solid Rocket Motor Segment mated together in the Vehicle Assembly Building at Kennedy Space Center and being prepared for mounting onto the Mobile Launch Platform and mating with the other Solid Rocket Booster segments. - Space Transportation System, Solid Rocket Boosters, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  7. 117. JOB NO. 1347M, SHEET 5, 1930, ADDITION FOR PRESSED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    117. JOB NO. 1347-M, SHEET 5, 1930, ADDITION FOR PRESSED STEEL DEPARTMENT FOR FORD MOTOR COMPANY; NORTH ELEVATIONS DETAILS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  8. 116. JOB NO. 1347M, SHEET 4, 1930, ADDITION FOR PRESSED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    116. JOB NO. 1347-M, SHEET 4, 1930, ADDITION FOR PRESSED STEEL DEPARTMENT FOR THE FORD MOTOR COMPANY; ELEVATIONS, DETAILS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  9. 3. VIEW TO WEST SHOWING EAST END OF OIL HOUSE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. VIEW TO WEST SHOWING EAST END OF OIL HOUSE (LEFT) AND EAST SIDE OF CRATING SHED AND ASSEMBLY BUILDING (RIGHT BACKGROUND). - Rosie the Riveter National Historical Park, Ford Assembly Plant, 1400 Harbour Way South, Richmond, Contra Costa County, CA

  10. 62. Neg. No. F75A, Jun 18, 1930, INTERIORWAREHOUSE, 1ST FLOOR, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    62. Neg. No. F-75A, Jun 18, 1930, INTERIOR-WAREHOUSE, 1ST FLOOR, STORAGE OF AUTOMOBILE COMPONENTS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  11. Precision Clean Hardware: Maintenance of Fluid Systems Cleanliness

    NASA Technical Reports Server (NTRS)

    Sharp, Sheila; Pedley, Mike; Bond, Tim; Quaglino, Joseph; Lorenz, Mary Jo; Bentz, Michael; Banta, Richard; Tolliver, Nancy; Golden, John; Levesque, Ray

    2003-01-01

    The ISS fluid systems are so complex that fluid system cleanliness cannot be verified at the assembly level. A "build clean / maintain clean" approach was used by all major fluid systems: Verify cleanliness at the detail and subassembly level. Maintain cleanliness during assembly.

  12. 2. VIEW, LOOKING NORTHWEST, FROM INSIDE THE PROTECTED AREA AT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. VIEW, LOOKING NORTHWEST, FROM INSIDE THE PROTECTED AREA AT THE BASE OF TOWER 901. THE BUILDINGS IN THE FOREGROUND INCLUDE 984, 992, 991, 989, AND 968. THESE BUILDINGS MAKE UP THE BUILDING 991 COMPLEX. BUILDING 991, PLANT D, WAS THE FIRST OPERATIONAL BUILDING ON SITE, CONSTRUCTED IN 1951 AS THE FINAL ASSEMBLY AND SHIPPING AND RECEIVING BUILDING. TO THE NORTH AND NORTHWEST OF BUILDING 991 ARE THE UNDERGROUND VAULTS AND TUNNELS USED TO STORAGE WEAPONS COMPONENTS. - Rocky Flats Plant, Bounded by Indiana Street & Routes 93, 128 & 72, Golden, Jefferson County, CO

  13. Building No. 1, left; Building No. 9, Guard House, center; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Building No. 1, left; Building No. 9, Guard House, center; Building No. 5, Main Building, right. View from across Main Street - Thomas A. Edison Laboratories, Main Street & Lakeside Avenue, West Orange, Essex County, NJ

  14. Role of Hydrophobic/Aromatic Residues on the Stability of Double-Wall β-Sheet Structures Formed by a Triblock Peptide.

    PubMed

    Ozgur, Beytullah; Sayar, Mehmet

    2017-04-27

    Bioinspired self-assembling peptides serve as powerful building blocks in the manufacturing of nanomaterials with tailored features. Because of their ease of synthesis, biocompatibility, and tunable activity, this emerging branch of biomolecules has become very popular. The triblock peptide architecture designed by the Hartgerink group is a versatile system that allows control over its assembly and has been shown to demonstrate tunable bioactivity. Three main forces, Coulomb repulsion, hydrogen bonding and hydrophobicity act together to guide the triblock peptides' assembly into one-dimensional objects and hydrogels. It was shown previously that both the nanofiber morphology (e.g., intersheet spacing, formation of antiparallel/parallel β-sheets) and hydrogel rheology strictly depend on the choice of the core residue where the triblock peptide fibers with aromatic cores in general form shorter fibers and yield poor hydrogels with respect to the ones with aliphatic cores. However, an elaborate understanding of the molecular reasons behind these changes remained unclear. In this study, by using carefully designed computer based free energy calculations, we analyzed the influence of the core residue on the formation of double-wall fibers and single-wall β-sheets. Our results demonstrate that the aromatic substitution impairs the fiber cores and this impairment is mainly associated with a reduced hydrophobic character of the aromatic side chains. Such weakening is most obvious in tryptophan containing peptides where the fiber core absorbs a significant amount of water. We also show that the ability of tyrosine to form side chain hydrogen bonds plays an indispensable role in the fiber stability. As opposed to the impairment of the fiber cores, single-wall β-sheets with aromatic faces become more stable compared to the ones with aliphatic faces suggesting that the choice of the core residue can also affect the underlying assembly mechanism. We also provide an in-depth comparison of competing structures (zero-dimensional aggregates, short and long fibers) in the triblock peptides' assembly and show that by adjusting the length of the terminal blocks, the fiber growth can be turned on or off while keeping the nanofiber morphology intact.

  15. Saturn V Vehicle for the Apollo 4 Mission in the Vehicle Assembly Building

    NASA Technical Reports Server (NTRS)

    1967-01-01

    This photograph depicts the Saturn V vehicle (SA-501) for the Apollo 4 mission in the Vehicle Assembly Building (VAB) at the Kennedy Space Center (KSC). After the completion of the assembly operation, the work platform was retracted and the vehicle was readied to rollout from the VAB to the launch pad. The Apollo 4 mission was the first launch of the Saturn V launch vehicle. Objectives of the unmanned Apollo 4 test flight were to obtain flight information on launch vehicle and spacecraft structural integrity and compatibility, flight loads, stage separation, and subsystems operation including testing of restart of the S-IVB stage, and to evaluate the Apollo command module heat shield. The Apollo 4 was launched on November 9, 1967 from KSC.

  16. Estimating shaking-induced casualties and building damage for global earthquake events: a proposed modelling approach

    USGS Publications Warehouse

    So, Emily; Spence, Robin

    2013-01-01

    Recent earthquakes such as the Haiti earthquake of 12 January 2010 and the Qinghai earthquake on 14 April 2010 have highlighted the importance of rapid estimation of casualties after the event for humanitarian response. Both of these events resulted in surprisingly high death tolls, casualties and survivors made homeless. In the Mw = 7.0 Haiti earthquake, over 200,000 people perished with more than 300,000 reported injuries and 2 million made homeless. The Mw = 6.9 earthquake in Qinghai resulted in over 2,000 deaths with a further 11,000 people with serious or moderate injuries and 100,000 people have been left homeless in this mountainous region of China. In such events relief efforts can be significantly benefitted by the availability of rapid estimation and mapping of expected casualties. This paper contributes to ongoing global efforts to estimate probable earthquake casualties very rapidly after an earthquake has taken place. The analysis uses the assembled empirical damage and casualty data in the Cambridge Earthquake Impacts Database (CEQID) and explores data by event and across events to test the relationships of building and fatality distributions to the main explanatory variables of building type, building damage level and earthquake intensity. The prototype global casualty estimation model described here uses a semi-empirical approach that estimates damage rates for different classes of buildings present in the local building stock, and then relates fatality rates to the damage rates of each class of buildings. This approach accounts for the effect of the very different types of buildings (by climatic zone, urban or rural location, culture, income level etc), on casualties. The resulting casualty parameters were tested against the overall casualty data from several historical earthquakes in CEQID; a reasonable fit was found.

  17. Remediation of subsurface and groundwater contamination with uranium from fuel fabrication facilities at Hanau (Germany)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nitzsche, Olaf; Thierfeldt, Stefan; Hummel, Lothar

    2013-07-01

    This paper presents aspects of site decommissioning and clearance of a former fuel fabrication facility (development and production of fuel assemblies for research reactors and HTR) at Hanau (Germany). The main pathways for environmental contamination were deposition on soil surface and topsoil and pollution of deep soil and the aquifer by waste water channel leakage. Soil excavation could be done by classical excavator techniques. An effective removal of material from the saturated zone was possible by using advanced drilling techniques. A large amount of demolished building structure and excavated soil had to be classified. Therefore the use of conveyor detectormore » was necessary. Nearly 100000 Mg of material (excavated soil and demolished building material) were disposed of at an underground mine. A remaining volume of 700 m{sup 3} was classified as radioactive waste. Site clearance started in 2006. Groundwater remediation and monitoring is still ongoing, but has already provided excellent results by reducing the remaining Uranium considerably. (authors)« less

  18. General view of the Space Shuttle Main Engine (SSME) assembly ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of the Space Shuttle Main Engine (SSME) assembly with the expansion nozzle removed and resting on a cushioned mat on the floor of the SSME Processing Facility. The most prominent features in this view are the Low-pressure Fuel Turbopump discharge Duct looping from the upper left side of the engine assembly to the lower left side of the assembly, the Low-Pressure Oxidizer Turbopump (LPOTP) is on the upper left of the assembly in this view and the LPOTP Discharge Duct loops from the upper left to upper right. The sphere in the middle right side of the assembly in this view is the POGO System Accumulator , the partial sphere to its left and slightly more toward the center of the assembly is the Heat Exchanger on the Oxidizer Preburner side of the Hot Gas Manifold, beneath that is the High-Pressure Oxidizer Turbopump (HPOTP) and the HPOTP Discharge duct loops from the pump around to the lower left of the assembly. The Pneumatic Control Assembly is in the approximate center of the engine assembly in this view. - Space Transportation System, Space Shuttle Main Engine, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  19. Entanglement, space-time and the Mayer-Vietoris theorem

    NASA Astrophysics Data System (ADS)

    Patrascu, Andrei T.

    2017-06-01

    Entanglement appears to be a fundamental building block of quantum gravity leading to new principles underlying the nature of quantum space-time. One such principle is the ER-EPR duality. While supported by our present intuition, a proof is far from obvious. In this article I present a first step towards such a proof, originating in what is known to algebraic topologists as the Mayer-Vietoris theorem. The main result of this work is the re-interpretation of the various morphisms arising when the Mayer-Vietoris theorem is used to assemble a torus-like topology from more basic subspaces on the torus in terms of quantum information theory resulting in a quantum entangler gate (Hadamard and c-NOT).

  20. Molecular Assembly of Polysaccharide-Based Microcapsules and Their Biomedical Applications.

    PubMed

    Feng, Xiyun; Du, Cuiling; Li, Junbai

    2016-08-01

    Advanced multifunctional microcapsules have revealed great potential in biomedical applications owing to their tunable size, shape, surface properties, and stimuli responsiveness. Polysaccharides are one of the most acceptable biomaterials for biomedical applications because of their outstanding virtues such as biocompatibility, biodegradability, and low toxicity. Many efforts have been devoted to investigating novel molecular design and efficient building blocks for polysaccharide-based microcapsules. In this Personal Account, we first summarize the common features of polysaccharides and the main principles of the design and fabrication of polysaccharide-based microcapsules, and further discuss their applications in biomedical areas and perspectives for future research. © 2016 The Chemical Society of Japan & Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. STS-88 Mission Specialist Nancy J. Currie suits up for TCDT

    NASA Technical Reports Server (NTRS)

    1998-01-01

    STS-88 Mission Specialist Nancy J. Currie suits up in the Operations and Checkout Building, as part of flight crew equipment fit check, prior to her trip to Launch Pad 39A. She is helped by suit tech Drew Billingsley. The crew are at KSC to participate in the Terminal Countdown Demonstration Test (TCDT) which includes mission familiarization activities, emergency egress training, and the simulated main engine cut-off exercise. This is Currie's third space flight. Mission STS-88 is targeted for launch on Dec. 3, 1998. It is the first U.S. flight for the assembly of the International Space Station and will carry the Unity connecting module.

  2. RNA self-assembly and RNA nanotechnology.

    PubMed

    Grabow, Wade W; Jaeger, Luc

    2014-06-17

    CONSPECTUS: Nanotechnology's central goal involves the direct control of matter at the molecular nanometer scale to build nanofactories, nanomachines, and other devices for potential applications including electronics, alternative fuels, and medicine. In this regard, the nascent use of nucleic acids as a material to coordinate the precise arrangements of specific molecules marked an important milestone in the relatively recent history of nanotechnology. While DNA served as the pioneer building material in nucleic acid nanotechnology, RNA continues to emerge as viable alternative material with its own distinct advantages for nanoconstruction. Several complementary assembly strategies have been used to build a diverse set of RNA nanostructures having unique structural attributes and the ability to self-assemble in a highly programmable and controlled manner. Of the different strategies, the architectonics approach uniquely endeavors to understand integrated structural RNA architectures through the arrangement of their characteristic structural building blocks. Viewed through this lens, it becomes apparent that nature routinely uses thermodynamically stable, recurrent modular motifs from natural RNA molecules to generate unique and more complex programmable structures. With the design principles found in natural structures, a number of synthetic RNAs have been constructed. The synthetic nanostructures constructed to date have provided, in addition to affording essential insights into RNA design, important platforms to characterize and validate the structural self-folding and assembly properties of RNA modules or building blocks. Furthermore, RNA nanoparticles have shown great promise for applications in nanomedicine and RNA-based therapeutics. Nevertheless, the synthetic RNA architectures achieved thus far consist largely of static, rigid particles that are still far from matching the structural and functional complexity of natural responsive structural elements such as the ribosome, large ribozymes, and riboswitches. Thus, the next step in synthetic RNA design will involve new ways to implement these same types of dynamic and responsive architectures into nanostructures functioning as real nanomachines in and outside the cell. RNA nanotechnology will likely garner broader utility and influence with a greater focus on the interplay between thermodynamic and kinetic influences on RNA self-assembly and using natural RNAs as guiding principles.

  3. Evaluation of the deflected mode of the monolithic span pieces and preassembled slabs combined action

    NASA Astrophysics Data System (ADS)

    Roshchina, Svetlana; Ezzi, Hisham; Shishov, Ivan; Lukin, Mikhail; Sergeev, Michael

    2017-10-01

    In single-story industrial buildings, the cost of roof covering comprises 40-55% of the total cost of the buildings. Therefore, research, development and application of new structural forms of reinforced concrete rafter structures, that allow to reduce material consumption and reduce the sub-assembly weight of structures, are the main tasks in the field of improving the existing generic solutions. The article suggests a method for estimating the relieving effect in the rafter structure as the result of combined deformation of the roof slabs with the end arrises. Calculated and experimental method for determining the stress and strain state of the rafter structure upper belt and the roof slabs with regard to their rigid connection has been proposed. A model of a highly effective roof structure providing a significant reduction in the construction height of the roofing and the cubic content of the building at the same time allowing to include the end arrises and a part of the slabs shelves with the help of the monolithic concrete has been proposed. The proposed prefabricated monolithic concrete rafter structure and its rigid connection with ribbed slabs allows to reduce the consumption of the prestressed slabs reinforcement by 50%.

  4. Contextual view of building no. 541, looking southwest. Structure no. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view of building no. 541, looking southwest. Structure no. 1051 in left foreground and structure no. 1045 in right foreground. - Naval Base Philadelphia-Philadelphia Naval Shipyard, Structural Assembly Shop, League Island, Philadelphia, Philadelphia County, PA

  5. Black Maria Reconstruction (left foreground); Building No. 1; Main Building; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Black Maria Reconstruction (left foreground); Building No. 1; Main Building; Edison Storage Battery Building (right background) - Thomas A. Edison Laboratories, Main Street & Lakeside Avenue, West Orange, Essex County, NJ

  6. 2. Photocopy of early 20th century photo, showing the Euclid ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Photocopy of early 20th century photo, showing the Euclid Avenue facade of the branch assembly building. Photograph owned by the Cleveland Public Library. - Ford Motor Company, Cleveland Branch Assembly Plant, Euclid Avenue & East 116th Street, Cleveland, Cuyahoga County, OH

  7. 118. JOB NO. 1347M, SHEET 2, 1930/1931, ADDITION FOR PRESSED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    118. JOB NO. 1347-M, SHEET 2, 1930/1931, ADDITION FOR PRESSED STEEL DEPARTMENT FOR FORD MOTOR COMPANY; FIRST FLOOR PLAN - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  8. 119. JOB NO. 1347M, SHEET 6, 1930, ADDITION FOR PRESSED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    119. JOB NO. 1347-M, SHEET 6, 1930, ADDITION FOR PRESSED STEEL DEPARTMENT FOR FORD MOTOR COMPANY; ONE-FOURTH INCH ELEVATIONS, TRANSFORMER, DETAILS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  9. 120. JOB NO. 1347M, SHEET 7, 1930, ADDITION FOR PRESSED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    120. JOB NO. 1347-M, SHEET 7, 1930, ADDITION FOR PRESSED STEEL DEPARTMENT FOR THE FORD MOTOR COMPANY; SECTION AA AND ROOF DETAILS - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  10. 15. VIEW OF MODULE H, THE HIGH PRESSURE ASSEMBLY AREA. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. VIEW OF MODULE H, THE HIGH PRESSURE ASSEMBLY AREA. PROCESSES IN THIS MODULE OCCURRED UNDER HIGH PRESSURES AND TEMPERATURES. (5/70) - Rocky Flats Plant, Plutonium Manufacturing Facility, North-central section of Plant, just south of Building 776/777, Golden, Jefferson County, CO

  11. 22. TIME CLOCK AREA, WITH LUNCH ROOM IN DISTANCE. RAIL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. TIME CLOCK AREA, WITH LUNCH ROOM IN DISTANCE. RAIL SPUR FOLDING DOORS ARE HIDDEN BEHIND OFFICE AT PHOTO CENTER. VIEW TO EAST-NORTHEAST. - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  12. A phylogenetic community approach for studying termite communities in a West African savannah.

    PubMed

    Hausberger, Barbara; Korb, Judith

    2015-10-01

    Termites play fundamental roles in tropical ecosystems, and mound-building species in particular are crucial in enhancing species diversity, from plants to mammals. However, it is still unclear which factors govern the occurrence and assembly of termite communities. A phylogenetic community approach and null models of species assembly were used to examine structuring processes associated with termite community assembly in a pristine savannah. Overall, we did not find evidence for a strong influence of interspecific competition or environmental filtering in structuring these communities. However, the presence of a single species, the mound-building termite Macrotermes bellicosus, left a strong signal on structuring and led to clustered communities of more closely related species. Hence, this species changes the assembly rules for a whole community. Our results show the fundamental importance of a single insect species for community processes, suggesting that more attention to insect species is warranted when developing conservation strategies. © 2015 The Author(s).

  13. Structure of the RZZ complex and molecular basis of its interaction with Spindly

    PubMed Central

    Mosalaganti, Shyamal; Keller, Jenny; Altenfeld, Anika; Rombaut, Pascaline; Petrovic, Arsen; Wohlgemuth, Sabine; Müller, Franziska; Herzog, Franz; Waldmann, Herbert

    2017-01-01

    Kinetochores are macromolecular assemblies that connect chromosomes to spindle microtubules (MTs) during mitosis. The metazoan-specific ≈800-kD ROD–Zwilch–ZW10 (RZZ) complex builds a fibrous corona that assembles on mitotic kinetochores before MT attachment to promote chromosome alignment and robust spindle assembly checkpoint signaling. In this study, we combine biochemical reconstitutions, single-particle electron cryomicroscopy, cross-linking mass spectrometry, and structural modeling to build a complete model of human RZZ. We find that RZZ is structurally related to self-assembling cytosolic coat scaffolds that mediate membrane cargo trafficking, including Clathrin, Sec13–Sec31, and αβ’ε-COP. We show that Spindly, a dynein adaptor, is related to BicD2 and binds RZZ directly in a farnesylation-dependent but membrane-independent manner. Through a targeted chemical biology approach, we identify ROD as the Spindly farnesyl receptor. Our results suggest that RZZ is dynein’s cargo at human kinetochores. PMID:28320825

  14. Thermally induced magnetic relaxation in square artificial spin ice.

    PubMed

    Andersson, M S; Pappas, S D; Stopfel, H; Östman, E; Stein, A; Nordblad, P; Mathieu, R; Hjörvarsson, B; Kapaklis, V

    2016-11-24

    The properties of natural and artificial assemblies of interacting elements, ranging from Quarks to Galaxies, are at the heart of Physics. The collective response and dynamics of such assemblies are dictated by the intrinsic dynamical properties of the building blocks, the nature of their interactions and topological constraints. Here we report on the relaxation dynamics of the magnetization of artificial assemblies of mesoscopic spins. In our model nano-magnetic system - square artificial spin ice - we are able to control the geometrical arrangement and interaction strength between the magnetically interacting building blocks by means of nano-lithography. Using time resolved magnetometry we show that the relaxation process can be described using the Kohlrausch law and that the extracted temperature dependent relaxation times of the assemblies follow the Vogel-Fulcher law. The results provide insight into the relaxation dynamics of mesoscopic nano-magnetic model systems, with adjustable energy and time scales, and demonstrates that these can serve as an ideal playground for the studies of collective dynamics and relaxations.

  15. Thermally induced magnetic relaxation in square artificial spin ice

    NASA Astrophysics Data System (ADS)

    Andersson, M. S.; Pappas, S. D.; Stopfel, H.; Östman, E.; Stein, A.; Nordblad, P.; Mathieu, R.; Hjörvarsson, B.; Kapaklis, V.

    2016-11-01

    The properties of natural and artificial assemblies of interacting elements, ranging from Quarks to Galaxies, are at the heart of Physics. The collective response and dynamics of such assemblies are dictated by the intrinsic dynamical properties of the building blocks, the nature of their interactions and topological constraints. Here we report on the relaxation dynamics of the magnetization of artificial assemblies of mesoscopic spins. In our model nano-magnetic system - square artificial spin ice - we are able to control the geometrical arrangement and interaction strength between the magnetically interacting building blocks by means of nano-lithography. Using time resolved magnetometry we show that the relaxation process can be described using the Kohlrausch law and that the extracted temperature dependent relaxation times of the assemblies follow the Vogel-Fulcher law. The results provide insight into the relaxation dynamics of mesoscopic nano-magnetic model systems, with adjustable energy and time scales, and demonstrates that these can serve as an ideal playground for the studies of collective dynamics and relaxations.

  16. KENNEDY SPACE CENTER, FLA. - In the Vehicle Assembly Building, after being removed from the solid rocket booster (SRB), the forward assembly is lowered toward a transporter below in the transfer aisle. The destacking is part of time and cycle activities. The SRB was part of the stack on Atlantis originally scheduled for a March 1, 2003, launch on mission STS-114. The SRBs and external tank were demated in February 2003. The mission is now scheduled to occur no earlier than Sept. 12, 2004, on Atlantis.

    NASA Image and Video Library

    2003-12-09

    KENNEDY SPACE CENTER, FLA. - In the Vehicle Assembly Building, after being removed from the solid rocket booster (SRB), the forward assembly is lowered toward a transporter below in the transfer aisle. The destacking is part of time and cycle activities. The SRB was part of the stack on Atlantis originally scheduled for a March 1, 2003, launch on mission STS-114. The SRBs and external tank were demated in February 2003. The mission is now scheduled to occur no earlier than Sept. 12, 2004, on Atlantis.

  17. KENNEDY SPACE CENTER, FLA. - In the Vehicle Assembly Building, after being removed from the solid rocket booster (SRB), the forward assembly is lowered from high above the transfer aisle. The destacking is part of time and cycle activities. The SRB was part of the stack on Atlantis originally scheduled for a March 1, 2003, launch on mission STS-114. The SRBs and external tank were demated in February 2003. The mission is now scheduled to occur no earlier than Sept. 12, 2004, on Atlantis.

    NASA Image and Video Library

    2003-12-09

    KENNEDY SPACE CENTER, FLA. - In the Vehicle Assembly Building, after being removed from the solid rocket booster (SRB), the forward assembly is lowered from high above the transfer aisle. The destacking is part of time and cycle activities. The SRB was part of the stack on Atlantis originally scheduled for a March 1, 2003, launch on mission STS-114. The SRBs and external tank were demated in February 2003. The mission is now scheduled to occur no earlier than Sept. 12, 2004, on Atlantis.

  18. Molecular dynamics simulation studies of tailored nanostructured polymers

    NASA Astrophysics Data System (ADS)

    Liu, Lixin

    With recent advancements in the synthesis and characterization of polymeric materials, scientists are able to create multi-scale novel polymers with various cases of chemical functionalities, diversified topologies, as well as cross-linking networks. Due to those remarkable achievements, there are a broad range of possible applications of smart polymers in catalysis, in environmental remediation, and especially in drug-delivery. Because of rising interest in developing therapeutic drug binding to specific treating target, polymer chemists are in particular interests in design and engineering the drug delivery materials to be not only bio-compatible, but also to be capable of self-assembly at various in-vivo physiological stimulus. Both experimental and theoretical work indicate that the thermodynamic properties relating to the hydrophobic effect play an important role in determining self-assembly process. At the same time, computational simulation and modeling are powerful instruments to contribute to microscopic thermodynamics' understanding toward self-assembly phenomenon. Along with statistical approaches, constructing empirical model based on simulation results would also help predict for further development of tailored nano-structured materials. My Research mainly focused on investigating physical and chemical characteristics of polymer materials through molecular dynamics simulation and probing the fundamental thermodynamic driving force of self-assembly behavior. We tried to surmount technological obstacles in computational chemistry and build an efficient scheme to identify the physical and chemical Feature of molecules, to reproduce underlying properties, to understand the origin of thermodynamic signatures, and to speed up current trial and error process in screening new materials.

  19. Self-Assembled Nano-energetic Gas Generators based on Bi2O3

    NASA Astrophysics Data System (ADS)

    Hobosyan, Mkhitar; Trevino, Tyler; Martirosyan, Karen

    2012-10-01

    Nanoenergetic Gas-Generators are formulations that rapidly release a large amount of gaseous products and generate a fast moving thermal wave. They are mainly based on thermite systems, which are pyrotechnic mixtures of metal powders (fuel- Al, Mg, etc.) and metal oxides (oxidizer, Bi2O3, Fe2O3, WO3, MoO3 etc.) that can generate an exothermic oxidation-reduction reaction referred to as a thermite reaction. A thermite reaction releases a large amount of energy and can generate rapidly extremely high temperatures. The intimate contact between the fuel and oxidizer can be enhanced by use of nano instead of micro particles. The contact area between oxidizer and metal particles depends from method of mixture preparation. In this work we utilize the self-assembly processes, which use the electrostatic forces to produce ordered and self-organized binary systems. In this process the intimate contact significantly enhances and gives the ability to build an energetic material in molecular level, which is crucial for thepressure discharge efficiency of nano-thermites. The DTA-TGA, Zeta-size analysis and FTIR technique were performed to characterize the Bi2O3 particles. The self-assembly of Aluminum and Bi2O3 was conducted in sonic bath with appropriate solvents and linkers. The resultant thermite pressure discharge values were tested in modified Parr reactor. In general, the self-assembled thermites give much higher-pressure discharge values than the thermites prepared with conventional roll-mixing technique.

  20. A Nonconventional Approach to Patterned Nanoarrays of DNA Strands for Template-Assisted Assembly of Polyfluorene Nanowires.

    PubMed

    Bae, Dong Geun; Jeong, Ji-Eun; Kang, Seok Hee; Byun, Myunghwan; Han, Dong-Wook; Lin, Zhiqun; Woo, Han Young; Hong, Suck Won

    2016-08-01

    DNA molecules have been widely recognized as promising building blocks for constructing functional nanostructures with two main features, that is, self-assembly and rich chemical functionality. The intrinsic feature size of DNA makes it attractive for creating versatile nanostructures. Moreover, the ease of access to tune the surface of DNA by chemical functionalization offers numerous opportunities for many applications. Herein, a simple yet robust strategy is developed to yield the self-assembly of DNA by exploiting controlled evaporative assembly of DNA solution in a unique confined geometry. Intriguingly, depending on the concentration of DNA solution, highly aligned nanostructured fibrillar-like arrays and well-positioned concentric ring-like superstructures composed of DNAs are formed. Subsequently, the ring-like negatively charged DNA superstructures are employed as template to produce conductive organic nanowires on a silicon substrate by complexing with a positively charged conjugated polyelectrolyte poly[9,9-bis(6'-N,N,N-trimethylammoniumhexyl)fluorene dibromide] (PF2) through the strong electrostatic interaction. Finally, a monolithic integration of aligned arrays of DNA-templated PF2 nanowires to yield two DNA/PF2-based devices is demonstrated. It is envisioned that this strategy can be readily extended to pattern other biomolecules and may render a broad range of potential applications from the nucleotide sequence and hybridization as recognition events to transducing elements in chemical sensors. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Top