37 CFR 2.200 - Assignment records open to public inspection.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 37 Patents, Trademarks, and Copyrights 1 2012-07-01 2012-07-01 false Assignment records open to... the Patent and Trademark Office § 2.200 Assignment records open to public inspection. (a)(1) Separate...) are open to public inspection at the Office, and copies of those assignment records may be obtained...
37 CFR 1.12 - Assignment records open to public inspection.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 37 Patents, Trademarks, and Copyrights 1 2012-07-01 2012-07-01 false Assignment records open to... Records and Files of the Patent and Trademark Office § 1.12 Assignment records open to public inspection..., are open to public inspection at the United States Patent and Trademark Office, and copies of patent...
37 CFR 2.200 - Assignment records open to public inspection.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Assignment records open to public inspection. 2.200 Section 2.200 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND... the Patent and Trademark Office § 2.200 Assignment records open to public inspection. (a)(1) Separate...
37 CFR 2.200 - Assignment records open to public inspection.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Assignment records open to public inspection. 2.200 Section 2.200 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND... the Patent and Trademark Office § 2.200 Assignment records open to public inspection. (a)(1) Separate...
37 CFR 2.200 - Assignment records open to public inspection.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Assignment records open to public inspection. 2.200 Section 2.200 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND... the Patent and Trademark Office § 2.200 Assignment records open to public inspection. (a)(1) Separate...
37 CFR 2.200 - Assignment records open to public inspection.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Assignment records open to public inspection. 2.200 Section 2.200 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND... the Patent and Trademark Office § 2.200 Assignment records open to public inspection. (a)(1) Separate...
37 CFR 1.12 - Assignment records open to public inspection.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Assignment records open to public inspection. 1.12 Section 1.12 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES General Provisions...
37 CFR 1.12 - Assignment records open to public inspection.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Assignment records open to public inspection. 1.12 Section 1.12 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES General Provisions...
37 CFR 1.12 - Assignment records open to public inspection.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Assignment records open to public inspection. 1.12 Section 1.12 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES General Provisions...
37 CFR 1.12 - Assignment records open to public inspection.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Assignment records open to public inspection. 1.12 Section 1.12 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES General Provisions...
Code of Federal Regulations, 2010 CFR
2010-01-01
... individual or other identifying particular assigned to the individual; (l) Statistical record means a record in a system of records maintained for statistical research or reporting purposes only and not used in... when the Board is open for the conduct of Government business and does not include Saturdays, Sundays...
The Introduction and Refinement of the Assessment of Digitally Recorded Audio Presentations
ERIC Educational Resources Information Center
Sinclair, Stefanie
2016-01-01
This case study critically evaluates benefits and challenges of a form of assessment included in a final year undergraduate Religious Studies Open University module, which combines a written essay task with a digital audio recording of a short oral presentation. Based on the analysis of student and tutor feedback and sample assignments, this study…
Springer, Kathleen B.
2016-01-01
Late Pleistocene groundwater discharge deposits (paleowetlands) in the upper Las Vegas Wash north of Las Vegas, Nevada, have yielded an abundant and diverse vertebrate fossil assemblage, the Tule Springs local fauna (TSLF). The TSLF is the largest open-site vertebrate fossil assemblage dating to the Rancholabrean North American Land Mammal Age in the southern Great Basin and Mojave Desert. Over 600 discrete body fossil localities have been recorded from the wash, including an area that now encompasses Tule Springs Fossil Beds National Monument (TUSK). Paleowetland sediments exposed in TUSK named the Las Vegas Formation span the last 250 ka, with fossiliferous sediments spanning ∼100–13 ka. The recovered fauna is dominated by remains of Camelopsand Mammuthus, and also includes relatively common remains of extinct Equusand Bisonas well as abundant vertebrate microfaunal fossils. Large carnivorans are rare, with only Puma concolor and Panthera atrox documented previously. Postcranial remains assigned to the species Canis dirus (dire wolf) and Smilodon fatalis (sabre-toothed cat) represent the first confirmed records of these species from the TSLF, as well as the first documentation of Canis dirus in Nevada and the only known occurrence of Smilodonin southern Nevada. The size of the recovered canid fossil precludes assignment to other Pleistocene species of Canis. The morphology of the felid elements differentiates them from other large predators such as Panthera, Homotherium, and Xenosmilus, and the size of the fossils prevents assignment to other species of Smilodon. The confirmed presence of S. fatalis in the TSLF is of particular interest, indicating that this species inhabited open habitats. In turn, this suggests that the presumed preference of S. fatalis for closed-habitat environments hunting requires further elucidation. PMID:27366649
Scott, Eric; Springer, Kathleen
2016-01-01
Late Pleistocene groundwater discharge deposits (paleowetlands) in the upper Las Vegas Wash north of Las Vegas, Nevada, have yielded an abundant and diverse vertebrate fossil assemblage, the Tule Springs local fauna (TSLF). The TSLF is the largest open-site vertebrate fossil assemblage dating to the Rancholabrean North American Land Mammal Age in the southern Great Basin and Mojave Desert. Over 600 discrete body fossil localities have been recorded from the wash, including an area that now encompasses Tule Springs Fossil Beds National Monument (TUSK). Paleowetland sediments exposed in TUSK named the Las Vegas Formation span the last 250 ka, with fossiliferous sediments spanning ∼100–13 ka. The recovered fauna is dominated by remains of Camelopsand Mammuthus, and also includes relatively common remains of extinct Equusand Bisonas well as abundant vertebrate microfaunal fossils. Large carnivorans are rare, with only Puma concolor and Panthera atrox documented previously. Postcranial remains assigned to the species Canis dirus (dire wolf) and Smilodon fatalis(sabre-toothed cat) represent the first confirmed records of these species from the TSLF, as well as the first documentation of Canis dirus in Nevada and the only known occurrence of Smilodonin southern Nevada. The size of the recovered canid fossil precludes assignment to other Pleistocene species of Canis. The morphology of the felid elements differentiates them from other large predators such as Panthera, Homotherium, and Xenosmilus, and the size of the fossils prevents assignment to other species of Smilodon. The confirmed presence of S. fatalis in the TSLF is of particular interest, indicating that this species inhabited open habitats. In turn, this suggests that the presumed preference of S. fatalis for closed-habitat environments hunting requires further elucidation.
Unlocking the Gates: How and Why Leading Universities Are Opening up Access to Their Courses
ERIC Educational Resources Information Center
Walsh, Taylor
2011-01-01
Over the past decade, a small revolution has taken place at some of the world's leading universities, as they have started to provide free access to undergraduate course materials--including syllabi, assignments, and lectures--to anyone with an Internet connection. Yale offers high-quality audio and video recordings of a careful selection of…
Comparison of the effects of adrafinil, propentofylline, and nicergoline on behavior in aged dogs.
Siwak, C T; Gruet, P; Woehrlé, F; Muggenburg, B A; Murphey, H L; Milgram, N W
2000-11-01
To compare the efficacy of adrafinil, propentofylline, and nicergoline for enhancing behavior of aged dogs. 36 Beagles between 9 and 16 years old. Dogs were randomly assigned to receive adrafinil (20 mg/kg of body weight, PO, q 24 h; n = 12), propentofylline (5 mg/kg, PO, q 12 h; 12), or nicergoline (0.5 mg/kg, PO, q 24 h; 12) for 33 days. Baseline behaviors in an open field and in kennels (home cage) were recorded before treatment. After treatment, behaviors in the open field were recorded 2 hours after drug administration on days 2, 15, and 28, and 10 hours after administration on days 7, 20, and 33. Behaviors in the home cage were recorded 2 and 7 hours after drug administration on days 4, 17, and 30. Treatment with adrafinil resulted in a significant increase in locomotion in each of the open-field tests and an increase in locomotion in the home cage. This latter increase was smaller and more variable than that in the open field. Locomotion was not affected by treatment with propentofylline or nicergoline. In the open field, sniffing decreased over time in all 3 groups, but the largest decline was observed in the propentofylline group. Treatment with adrafinil may improve the quality of life of aged dogs by increasing exploratory behavior and alertness.
Semi-Formal Description of KVM/370 Trusted Processes
1977-12-09
OF KVM/370 TRUSTED PROCESSES 9I OTICD. H. THOMPSON SELECTEU JAN 5 IM8 , 9 DECEMBER 1977 D CLEARED FOR OPEN...Record Process TM-6062/111/00 OP15a: Start (Re der) given: Raddr: DeviceAddress NewClasses: set of Class entry: for some (R:ReaderEmtry) In Readers...Corporatio PRPU1: Process request for output spooling device assignment given: Process : ProcessName RequestedClassest set of Class entry: true error on for
Jing, Xia; Cimino, James J; Del Fiol, Guilherme
2015-11-30
The Librarian Infobutton Tailoring Environment (LITE) is a Web-based knowledge capture, management, and configuration tool with which users can build profiles used by OpenInfobutton, an open source infobutton manager, to provide electronic health record users with context-relevant links to online knowledge resources. We conducted a multipart evaluation study to explore users' attitudes and acceptance of LITE and to guide future development. The evaluation consisted of an initial online survey to all LITE users, followed by an observational study of a subset of users in which evaluators' sessions were recorded while they conducted assigned tasks. The observational study was followed by administration of a modified System Usability Scale (SUS) survey. Fourteen users responded to the survey and indicated good acceptance of LITE with feedback that was mostly positive. Six users participated in the observational study, demonstrating average task completion time of less than 6 minutes and an average SUS score of 72, which is considered good compared with other SUS scores. LITE can be used to fulfill its designated tasks quickly and successfully. Evaluators proposed suggestions for improvements in LITE functionality and user interface.
7 CFR 97.130 - Recording of assignments.
Code of Federal Regulations, 2010 CFR
2010-01-01
... PLANT VARIETY AND PROTECTION Assignments and Recording § 97.130 Recording of assignments. (a) Any assignment of an application for a certificate, or of a certificate of plant variety protection, or of any interest in a variety, or any license or grant and conveyance of any right to use of the variety, may be...
Rea, D G; Belsky, T; Calvin, M
1964-01-01
The nature and assignment of the Martian spectral features observed by W. M. Sinton in the 3-4 micron region have been re-examined. It is shown that it is not possible to state unequivocally that there are absorption bands at 2710 (3.69 microns), 2790 (3.58 microns) and 2900 (3.45 microns) cm-1. Rather the possibility of the presence of true reflection features complicates the issue and enables only a wide range to be specified for the corresponding resonant frequencies. To clarify the assignment of these a large number of pure organic and inorganic solids, together with a selection of biological samples, have been recorded in reflection. The assignment of the features to organic matter, implying the presence of life on the Martian maria, is found to be improbable. While inorganic carbonates have bands in this region, they also do not provide a satisfactory explanation of the observations. The assignment of these Martian spectral features is then an open question.
41 CFR 109-38.202-3 - Records.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Records. 109-38.202-3....202-3 Records. (a) The DPMO assigns “blocks” of U.S. Government license tag numbers to DOE organizations and maintains a current record of such assignments. Additional “blocks” will be assigned upon...
41 CFR 109-38.202-3 - Records.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Records. 109-38.202-3....202-3 Records. (a) The DPMO assigns “blocks” of U.S. Government license tag numbers to DOE organizations and maintains a current record of such assignments. Additional “blocks” will be assigned upon...
Jakusz, J.W.; Dieck, J.J.; Langrehr, H.A.; Ruhser, J.J.; Lubinski, S.J.
2016-01-11
Similar to an AA, validation involves generating random points based on the total area for each map class. However, instead of collecting field data, two or three individuals not involved with the photo-interpretative mapping separately review each of the points onscreen and record a best-fit vegetation type(s) for each site. Once the individual analyses are complete, results are joined together and a comparative analysis is performed. The objective of this initial analysis is to identify areas where the validation results were in agreement (matches) and areas where validation results were in disagreement (mismatches). The two or three individuals then perform an analysis, looking at each mismatched site, and agree upon a final validation class. (If two vegetation types at a specific site appear to be equally prevalent, the validation team is permitted to assign the site two best-fit vegetation types.) Following the validation team’s comparative analysis of vegetation assignments, the data are entered into a database and compared to the mappers’ vegetation assignments. Agreements and disagreements between the map and validation classes are identified, and a contingency table is produced. This document presents the AA processes/results for Pools 13 and La Grange, as well as the validation process/results for Pools 13 and 26 and Open River South.
The therapeutic value of adolescents' blogging about social-emotional difficulties.
Boniel-Nissim, Meyran; Barak, Azy
2013-08-01
Research shows that writing a personal diary is a valuable therapeutic means for relieving emotional distress and promoting well-being, and that diary writing during adolescence helps in coping with developmental challenges. Current technologies and cultural trends make it possible and normative to publish personal diaries on the Internet through blogs--interactive, online forms of the traditional personal diary. We examined the therapeutic value of blogging for adolescents who experience social-emotional difficulties. The field experiment included randomly assigned adolescents, preassessed as having social-emotional difficulties, to 6 groups (26-28 participants in each): Four groups were assigned to blogging (writing about their difficulties or free writing; either open or closed to responses), a group assigned to writing a diary on personal computers, and a no-treatment control group. Participants in the 5 writing groups were instructed to post messages at least twice a week over 10 weeks. Outcome measures included scales of social-emotional difficulties and self-esteem, a social activities checklist, and textual analyses of participants' posts. Measurement took place at pre- and postintervention and at follow-up 2 months later. Results showed that participants maintaining a blog significantly improved on all measures. Participants writing about their difficulties in blogs open to responses gained the most. These results were consistent in the follow-up evaluation. PsycINFO Database Record (c) 2013 APA, all rights reserved.
The Assignment Pack. Materials for Flexible and Open Learning.
ERIC Educational Resources Information Center
Adult Literacy and Basic Skills Unit, London (England).
This assignment pack is designed for students and tutors working in open, flexible, or distance learning in Britain. Each of the six sections contains the following: (1) a detailed contents page that identifies the assignment under an activity heading, an individual title, and indication of the relationship to the City and Guilds of London…
ERIC Educational Resources Information Center
Pappas, Ilias O.; Giannakos, Michail N.; Mikalef, Patrick
2017-01-01
The use of video-based open educational resources is widespread, and includes multiple approaches to implementation. In this paper, the term "with-video assignments" is introduced to portray video learning resources enhanced with assignments. The goal of this study is to examine the factors that influence students' intention to adopt…
Ravelli, Angelo; Davì, Sergio; Bracciolini, Giulia; Pistorio, Angela; Consolaro, Alessandro; van Dijkhuizen, Evert Hendrik Pieter; Lattanzi, Bianca; Filocamo, Giovanni; Verazza, Sara; Gerloni, Valeria; Gattinara, Maurizio; Pontikaki, Irene; Insalaco, Antonella; De Benedetti, Fabrizio; Civino, Adele; Presta, Giuseppe; Breda, Luciana; Marzetti, Valentina; Pastore, Serena; Magni-Manzoni, Silvia; Maggio, Maria Cristina; Garofalo, Franco; Rigante, Donato; Gattorno, Marco; Malattia, Clara; Picco, Paolo; Viola, Stefania; Lanni, Stefano; Ruperto, Nicolino; Martini, Alberto
2017-03-04
Little evidence-based information is available to guide the treatment of oligoarticular juvenile idiopathic arthritis. We aimed to investigate whether oral methotrexate increases the efficacy of intra-articular corticosteroid therapy. We did this prospective, open-label, randomised trial at ten hospitals in Italy. Using a concealed computer-generated list, children younger than 18 years with oligoarticular-onset disease were randomly assigned (1:1) to intra-articular corticosteroids alone or in combination with oral methotrexate (15 mg/m 2 ; maximum 20 mg). Corticosteroids used were triamcinolone hexacetonide (shoulder, elbow, wrist, knee, and tibiotalar joints) or methylprednisolone acetate (ie, subtalar and tarsal joints). We did not mask patients or investigators to treatment assignments. Our primary outcome was the proportion of patients in the intention-to-treat population who had remission of arthritis in all injected joints at 12 months. This trial is registered with European Union Clinical Trials Register, EudraCT number 2008-006741-70. Between July 7, 2009, and March 31, 2013, we screened 226 participants and randomly assigned 102 to intra-articular corticosteroids alone and 105 to intra-articular corticosteroids plus methotrexate. 33 (32%) patients assigned to intra-articular corticosteroids alone and 39 (37%) assigned to intra-articular corticosteroids and methotrexate therapy had remission of arthritis in all injected joints (p=0·48). Adverse events were recorded for 20 (17%) patients who received methotrexate, which led to permanent treatment discontinuation in two patients (one due to increased liver transaminases and one due to gastrointestinal discomfort). No patient had a serious adverse event. Concomitant administration of methotrexate did not augment the effectiveness of intra-articular corticosteroid therapy. Future studies are needed to define the optimal therapeutic strategies for oligoarticular juvenile idiopathic arthritis. Italian Agency of Drug Evaluation. Copyright © 2017 Elsevier Ltd. All rights reserved.
Fish, Richard E; Foster, Melanie L; Gruen, Margaret E; Sherman, Barbara L; Dorman, Davidc C
2017-07-01
Safety pharmacology studies in dogs often integrate behavioral assessments made using video recording with physiologic measurements collected by telemetry. However, whether merely wearing the telemetry vest affects canine behavior and other parameters has not been evaluated. This pilot study assessed the effect of a telemetry vest on behavioral and physiologic responses to an environmental stressor, the sounds of a thunderstorm, in Labrador retrievers. Dogs were assigned to one of 2 experimental groups (Vest and No-Vest, n = 8 dogs per group) by using a matched pairs design, with a previously determined, sound-associated anxiety score as the blocking variable. Dogs were individually retested with the same standardized sound stimulus (thunderstorm) in an open-field arena, and their behavioral responses were video recorded. Video analysis of locomotor activity and anxiety-related behavior and manual determination of heart rate and body temperature were performed; results were compared between groups. Vest wearing did not affect total locomotor activity or rectal body temperature but significantly decreased heart rate by 8% and overall mean anxiety score by 34% during open-field test sessions. Our results suggest that the use of telemetry vests in dogs influences the measurement of physiologic parameters and behaviors that are assessed in safety pharmacology studies.
Jeannerat, Damien
2017-01-01
The introduction of a universal data format to report the correlation data of 2D NMR spectra such as COSY, HSQC and HMBC spectra will have a large impact on the reliability of structure determination of small organic molecules. These lists of assigned cross peaks will bridge signals found in NMR 1D and 2D spectra and the assigned chemical structure. The record could be very compact, human and computer readable so that it can be included in the supplementary material of publications and easily transferred into databases of scientific literature and chemical compounds. The records will allow authors, reviewers and future users to test the consistency and, in favorable situations, the uniqueness of the assignment of the correlation data to the associated chemical structures. Ideally, the data format of the correlation data should include direct links to the NMR spectra to make it possible to validate their reliability and allow direct comparison of spectra. In order to take the full benefits of their potential, the correlation data and the NMR spectra should therefore follow any manuscript in the review process and be stored in open-access database after publication. Keeping all NMR spectra, correlation data and assigned structures together at all time will allow the future development of validation tools increasing the reliability of past and future NMR data. This will facilitate the development of artificial intelligence analysis of NMR spectra by providing a source of data than can be used efficiently because they have been validated or can be validated by future users. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.
Rajappa, Medha; Bobby, Zachariah; Nandeesha, H; Suryapriya, R; Ragul, Anithasri; Yuvaraj, B; Revathy, G; Priyadarssini, M
2016-07-08
Graduate medical students of India are taught Biochemistry by didactic lectures and they hardly get any opportunity to clarify their doubts and reinforce the concepts which they learn in these lectures. We used a combination of teaching-learning (T-L) methods (open book assignment followed by group tutorials) to study their efficacy in improving the learning outcome. About 143 graduate medical students were classified into low (<50%: group 1, n = 23), medium (50-75%: group 2, n = 74), and high (>75%: group 3, n = 46) achievers, based on their internal assessment marks. After the regular teaching module on the topics "Vitamins and Enzymology", all the students attempted an open book assignment without peer consultation. Then all the students participated in group tutorials. The effects on the groups were evaluated by pre and posttests at the end of each phase, with the same set of MCQs. Gain from group tutorials and overall gain was significantly higher in the low achievers, compared to other groups. High and medium achievers obtained more gain from open book assignment, than group tutorials. The overall gain was significantly higher than the gain obtained from open book assignment or group tutorials, in all three groups. All the three groups retained the gain even after 1 week of the exercise. Hence, optimal use of novel T-L methods (open book assignment followed by group tutorials) as revision exercises help in strengthening concepts in Biochemistry in this oft neglected group of low achievers in graduate medical education. © 2016 by The International Union of Biochemistry and Molecular Biology, 44(4):321-325, 2016. © 2016 The International Union of Biochemistry and Molecular Biology.
Hidden Markov analysis of mechanosensitive ion channel gating.
Khan, R Nazim; Martinac, Boris; Madsen, Barry W; Milne, Robin K; Yeo, Geoffrey F; Edeson, Robert O
2005-02-01
Patch clamp data from the large conductance mechanosensitive channel (MscL) in E. coli was studied with the aim of developing a strategy for statistical analysis based on hidden Markov models (HMMs) and determining the number of conductance levels of the channel, together with mean current, mean dwell time and equilibrium probability of occupancy for each level. The models incorporated state-dependent white noise and moving average adjustment for filtering, with maximum likelihood parameter estimates obtained using an EM (expectation-maximisation) based iteration. Adjustment for filtering was included as it could be expected that the electronic filter used in recording would have a major effect on obviously brief intermediate conductance level sojourns. Preliminary data analysis revealed that the brevity of intermediate level sojourns caused difficulties in assignment of data points to levels as a result of over-estimation of noise variances. When reasonable constraints were placed on these variances using the better determined noise variances for the closed and fully open levels, idealisation anomalies were eliminated. Nevertheless, simulations suggested that mean sojourn times for the intermediate levels were still considerably over-estimated, and that recording bandwidth was a major limitation; improved results were obtained with higher bandwidth data (10 kHz sampled at 25 kHz). The simplest model consistent with these data had four open conductance levels, intermediate levels being approximately 20%, 51% and 74% of fully open. The mean lifetime at the fully open level was about 1 ms; estimates for the three intermediate levels were 54-92 micros, probably still over-estimates.
77 FR 23765 - Privacy Act; Termination of Three Systems of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-20
... terminating the following Systems of Records: MSPB/Internal 5, ``Workload and Assignment Tracking System... Tracking System.'' They are no longer in use. DATES: Effective April 6, 2012. FOR FURTHER INFORMATION... systems of records: MSPB/Internal 5, ``Workload and Assignment Tracking System;'' MSPB/Internal 7...
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
Assessing the impact of energy efficiency technologies at a district or city scale is of great interest to local governments, real estate developers, utility companies, and policymakers. This paper describes a flexible framework that can be used to create and run district and city scale building energy simulations. The framework is built around the new OpenStudio City Database (CityDB). Building footprints, building height, building type, and other data can be imported from public records or other sources. Missing data can be inferred or assigned from a statistical sampling of other datasets. Once all required data is available, OpenStudio Measures aremore » used to create starting point energy models and to model energy efficiency measures for each building. Together this framework allows a user to pose several scenarios such as 'what if 30% of the commercial retail buildings added rooftop solar' or 'what if all elementary schools converted to ground source heat pumps' and then visualize the impacts at a district or city scale. This paper focuses on modeling existing building stock using public records. However, the framework is capable of supporting the evaluation of new construction, district systems, and the use of proprietary data sources.« less
Qadri, Firdausi; Ali, Mohammad; Chowdhury, Fahima; Khan, Ashraful Islam; Saha, Amit; Khan, Iqbal Ansary; Begum, Yasmin A; Bhuiyan, Taufiqur R; Chowdhury, Mohiul Islam; Uddin, Md Jasim; Khan, Jahangir A M; Chowdhury, Atique Iqbal; Rahman, Anisur; Siddique, Shah Alam; Asaduzzaman, Muhammad; Akter, Afroza; Khan, Arifuzzaman; Ae You, Young; Siddik, Ashraf Uddin; Saha, Nirod Chandra; Kabir, Alamgir; Riaz, Baizid Khoorshid; Biswas, Shwapon Kumar; Begum, Farzana; Unicomb, Leanne; Luby, Stephen P; Cravioto, Alejandro; Clemens, John D
2015-10-03
Cholera is endemic in Bangladesh with epidemics occurring each year. The decision to use a cheap oral killed whole-cell cholera vaccine to control the disease depends on the feasibility and effectiveness of vaccination when delivered in a public health setting. We therefore assessed the feasibility and protective effect of delivering such a vaccine through routine government services in urban Bangladesh and evaluated the benefit of adding behavioural interventions to encourage safe drinking water and hand washing to vaccination in this setting. We did this cluster-randomised open-label trial in Dhaka, Bangladesh. We randomly assigned 90 clusters (1:1:1) to vaccination only, vaccination and behavioural change, or no intervention. The primary outcome was overall protective effectiveness, assessed as the risk of severely dehydrating cholera during 2 years after vaccination for all individuals present at time of the second dose. This study is registered with ClinicalTrials.gov, number NCT01339845. Of 268,896 people present at baseline, we analysed 267,270: 94,675 assigned to vaccination only, 92,539 assigned to vaccination and behavioural change, and 80,056 assigned to non-intervention. Vaccine coverage was 65% in the vaccination only group and 66% in the vaccination and behavioural change group. Overall protective effectiveness was 37% (95% CI lower bound 18%; p=0·002) in the vaccination group and 45% (95% CI lower bound 24%; p=0·001) in the vaccination and behavioural change group. We recorded no vaccine-related serious adverse events. Our findings provide the first indication of the effect of delivering an oral killed whole-cell cholera vaccine to poor urban populations with endemic cholera using routine government services and will help policy makers to formulate vaccination strategies to reduce the burden of severely dehydrating cholera in such populations. Bill & Melinda Gates Foundation. Copyright © 2015 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Mukhopadhyay, Indra
2016-05-01
In this work the far infrared (FIR) absorption spectrum has been measured for the asymmetrically mono deuterated Methanol (CH2DOH) species in the wavenumber range of 15-1200 cm-1 better accuracy and signal/noise ratio than known before. Assignments have been made for b-type transitions in the lowest lying torsional vibrational state trans-(e0) for a wide range of rotational angular momentum. The assignments have been rigorously confirmed by the residual loop defect methods. The rR-branch wavenumbers are analyzed by the usual state dependent expansion parameters and the Q-Branch origins. These origins have been used to calculate the torsional and torsional-rotation interaction contributions. These findings are in good agreement with predicted from the Hamiltonian model described in recent publications. A large number of assignments have also been made in the millimeter wave spectrum recorded earlier and thereby evaluated the asymmetry splitting parameters for 4 different axial rotational angular momentum quantum numbers. The analysis and interpretation of the spectra are reported. New assignments for about 260 transitions are included the text and a catalog of about 1500 transitions belonging to the e0 species is prepared (Appendix 1) and is made available through the open server in "Research Gate" and will be freely available to others.
28 CFR 301.103 - Inmate work assignments.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Inmate work assignments. 301.103 Section... COMPENSATION General § 301.103 Inmate work assignments. The unit team of each inmate, which ordinarily designates work assignments, or whoever makes work assignments, shall review appropriate medical records...
28 CFR 301.103 - Inmate work assignments.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Inmate work assignments. 301.103 Section... COMPENSATION General § 301.103 Inmate work assignments. The unit team of each inmate, which ordinarily designates work assignments, or whoever makes work assignments, shall review appropriate medical records...
28 CFR 301.103 - Inmate work assignments.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Inmate work assignments. 301.103 Section... COMPENSATION General § 301.103 Inmate work assignments. The unit team of each inmate, which ordinarily designates work assignments, or whoever makes work assignments, shall review appropriate medical records...
28 CFR 301.103 - Inmate work assignments.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Inmate work assignments. 301.103 Section... COMPENSATION General § 301.103 Inmate work assignments. The unit team of each inmate, which ordinarily designates work assignments, or whoever makes work assignments, shall review appropriate medical records...
76 FR 55880 - Recording Assignments
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-09
... DEPARTMENT OF COMMERCE United States Patent and Trademark Office Recording Assignments ACTION: Proposed collection; comment request. SUMMARY: The United States Patent and Trademark Office (USPTO), as... Information Officer, United States Patent and Trademark Office, P.O. Box 1450, Alexandria, VA 22313-1450...
Hernandez, Matthew C; Aho, Johnathon M; Habermann, Elizabeth B; Choudhry, Asad J; Morris, David S; Zielinski, Martin D
2017-01-01
Determination and reporting of disease severity in emergency general surgery lacks standardization. Recently, the American Association for the Surgery of Trauma (AAST) proposed an anatomic severity grading system. We aimed to validate this system in patients with appendicitis and determine if cross-sectional imaging correlates with disease severity at operation. Patients 18 years or older undergoing treatment for acute appendicitis between 2013 and 2015 were identified. Baseline demographics, procedure types were recorded, and AAST grades were assigned based on intraoperative and radiologic findings. Outcomes including length of stay, 30-day mortality, and complications based on Clavien-Dindo categories and National Surgical Quality Improvement Program variables. Summary statistical univariate, nominal logistic, and standard least squares analyses were performed comparing AAST grade with key outcomes. Bland-Altman analysis compared operative findings with preoperative cross-sectional imaging to compare assigning grades. Three hundred thirty-four patients with mean (±SD) age of 39.3 years (±16.5) were included (53% men), and all patients had cross-sectional imaging. Two hundred ninety-nine underwent appendectomy, and 85% completed laparoscopic. Thirty-day mortality rate was 0.9%, complication rate was 21%. Increased (median [interquartile range, IQR]) AAST grade was recorded in patients with complications (2 [1-4]) compared with those without (1 [1-1], p = 0.001). For operative management, (median [IQR]) AAST grades were significantly associated with procedure type: laparoscopic (1 [1-1]), open (4 [2-5]), conversion to open (3 [1-4], p = 0.001). Increased (median [IQR]) AAST grades were significantly associated in nonoperative management: patients having a complication had a higher median AAST grade (4 [3-5]) compared with those without (3 [2-3], p = 0.001). Bland-Altman analysis comparing AAST grade and cross-sectional imaging demonstrated no difference (-0.02 ± 0.02; p = 0.2; coefficient of repeatability 0.9). The AAST grading system is valid in our population. Increased AAST grade is associated with open procedures, complications, and length of stay. The AAST emergency general surgery grade determined by preoperative imaging strongly correlated to operative findings. Epidemiologic/prognostic study, level III.
Hernandez, Matthew; Aho, Johnathan M.; Habermann, Elizabeth B.; Choudhry, Asad; Morris, David; Zielinski, Martin
2016-01-01
Background Determination and reporting of disease severity in emergency general surgery (EGS) lacks standardization. Recently, the American Association for the Surgery of Trauma (AAST) proposed an anatomic severity grading system. We aimed to validate this system in patients with appendicitis, and determine if cross sectional imaging correlates with disease severity at operation. Methods Patients 18 years or older undergoing treatment for acute appendicitis between 2013 and 2015 were identified. Baseline demographics, procedure types were recorded, and AAST grades were assigned based on intraoperative and radiologic findings. Outcomes including length of stay, 30 day mortality, and complications based on Clavien-Dindo categories and National Surgical Quality Improvement Program variables. Summary statistical univariate, nominal logistic and standard least squares analyses were performed comparing AAST grade with key outcomes. Bland-Altman analysis compared operative findings to preoperative cross sectional imaging to compare assigning grades. Results 334 patients with mean (±SD) age of 39.3 years (±16.5) were included (53% male) and all patients had cross sectional imaging. 299 underwent appendectomy, and 85% completed laparoscopic. 30 day mortality rate was 0.9%, complication rate 21%. Increased median [IQR] AAST grade was recorded in patients with complications 2 [1-4] compared to those without 1 [1-1], p=0.001. For operative management, a median [IQR] AAST grades were significantly associated with procedure type: laparoscopic 1 [1-1], open 4 [2-5] conversion to open 3 [1-4], p=0.001. Increased median [IQR] AAST grades were significantly associated in non-operative management: patients having a complication had a higher median AAST grade of 4 [3-5], compared to those without 3 [2-3], p=0.001. Bland Altman analysis comparing AAST grade and cross sectional imaging demonstrated no difference; −0.02 ±0.02 p = 0.2 coefficient of repeatability 0.9. Conclusions The AAST grading system is valid in our population. Increased AAST grade is associated with open procedures, complications, and length of stay. AAST EGS grade determined by preoperative imaging strongly correlated to operative findings. PMID:27805996
ERIC Educational Resources Information Center
Rajappa, Medha; Bobby, Zachariah; Nandeesha, H.; Suryapriya, R.; Ragul, Anithasri; Yuvaraj, B.; Revathy, G.; Priyadarssini, M.
2016-01-01
Graduate medical students of India are taught Biochemistry by didactic lectures and they hardly get any opportunity to clarify their doubts and reinforce the concepts which they learn in these lectures. We used a combination of teaching-learning (T-L) methods (open book assignment followed by group tutorials) to study their efficacy in improving…
75 FR 48657 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-11
... position, organization of assignment, date assigned, estimated departure date, job specialty, and relevant..., organization of assignment, date assigned, estimated departure date, job specialty, and relevant career data...-to-know. Retention and disposal: Information is retained until individual transfers or is separated...
Sustaining K-12 professional development in geology: Recurrent participation in Rockcamp
Repine, T.E.; Hemler, D.A.; Behling, R.E.
2004-01-01
A reconnaissance study of the geology professional development program known as RockCamp was initiated to examine the sustained, or recurrent, participation of K-12 science teachers. Open-ended interviews, concept mapping, and creative writing assignments were used to explore the perceptions of six teachers possessing an exceptional record of participation. Efficacy, fun, right time of life, and support emerged as unanimous reasons for recurrent participation. Content, friendship, and methodology were very important. College credit was not critical. These teachers' perceptions suggest their sustained involvement in the RockCamp Program is stimulated by situated learning experiences stressing a compare, contrast, connect, and construct pedagogy within a supportive learning community.
A controlled trial of automated classification of negation from clinical notes
Elkin, Peter L; Brown, Steven H; Bauer, Brent A; Husser, Casey S; Carruth, William; Bergstrom, Larry R; Wahner-Roedler, Dietlind L
2005-01-01
Background Identification of negation in electronic health records is essential if we are to understand the computable meaning of the records: Our objective is to compare the accuracy of an automated mechanism for assignment of Negation to clinical concepts within a compositional expression with Human Assigned Negation. Also to perform a failure analysis to identify the causes of poorly identified negation (i.e. Missed Conceptual Representation, Inaccurate Conceptual Representation, Missed Negation, Inaccurate identification of Negation). Methods 41 Clinical Documents (Medical Evaluations; sometimes outside of Mayo these are referred to as History and Physical Examinations) were parsed using the Mayo Vocabulary Server Parsing Engine. SNOMED-CT™ was used to provide concept coverage for the clinical concepts in the record. These records resulted in identification of Concepts and textual clues to Negation. These records were reviewed by an independent medical terminologist, and the results were tallied in a spreadsheet. Where questions on the review arose Internal Medicine Faculty were employed to make a final determination. Results SNOMED-CT was used to provide concept coverage of the 14,792 Concepts in 41 Health Records from John's Hopkins University. Of these, 1,823 Concepts were identified as negative by Human review. The sensitivity (Recall) of the assignment of negation was 97.2% (p < 0.001, Pearson Chi-Square test; when compared to a coin flip). The specificity of assignment of negation was 98.8%. The positive likelihood ratio of the negation was 81. The positive predictive value (Precision) was 91.2% Conclusion Automated assignment of negation to concepts identified in health records based on review of the text is feasible and practical. Lexical assignment of negation is a good test of true Negativity as judged by the high sensitivity, specificity and positive likelihood ratio of the test. SNOMED-CT had overall coverage of 88.7% of the concepts being negated. PMID:15876352
Fish, Richard E; Foster, Melanie L; Gruen, Margaret E; Sherman, Barbara L; Dorman, David C
2017-01-01
Safety pharmacology studies in dogs often integrate behavioral assessments made using video recording with physiologic measurements collected by telemetry. However, whether merely wearing the telemetry vest affects canine behavior and other parameters has not been evaluated. This pilot study assessed the effect of a telemetry vest on behavioral and physiologic responses to an environmental stressor, the sounds of a thunderstorm, in Labrador retrievers. Dogs were assigned to one of 2 experimental groups (Vest and No-Vest, n = 8 dogs per group) by using a matched pairs design, with a previously determined, sound-associated anxiety score as the blocking variable. Dogs were individually retested with the same standardized sound stimulus (thunderstorm) in an open-field arena, and their behavioral responses were video recorded. Video analysis of locomotor activity and anxiety-related behavior and manual determination of heart rate and body temperature were performed; results were compared between groups. Vest wearing did not affect total locomotor activity or rectal body temperature but significantly decreased heart rate by 8% and overall mean anxiety score by 34% during open-field test sessions. Our results suggest that the use of telemetry vests in dogs influences the measurement of physiologic parameters and behaviors that are assessed in safety pharmacology studies. PMID:28724487
28 CFR 301.103 - Inmate work assignments.
Code of Federal Regulations, 2010 CFR
2010-07-01
... designates work assignments, or whoever makes work assignments, shall review appropriate medical records... compatible with the inmate's physical ability or condition. [55 FR 9296, Mar. 12, 1990, as amended at 59 FR...
Lee, Jisan; Kim, James G Boram; Jin, Meiling; Ahn, Kiwhan; Kim, Byungjun; Kim, Sukwha; Kim, Jeongeun
2017-11-01
Healthcare consumers must be able to make decisions based on accurate health information. To assist with this, we designed and developed an integrated system connected with electronic medical records in hospitals to ensure delivery of accurate health information. The system-called the Consumer-centered Open Personal Health Record platform-is composed of two services: a portal for users with any disease and a mobile application for users with cleft lip/palate. To assess the benefits of these services, we used a quasi-experimental, pretest-posttest design, assigning participants to the portal (n = 50) and application (n = 52) groups. Both groups showed significantly increased knowledge, both objective (actual knowledge of health information) and subjective (perceived knowledge of health information), after the intervention. Furthermore, while both groups showed higher information needs satisfaction after the intervention, the application group was significantly more satisfied. Knowledge changes were more affected by participant characteristics in the application group. Our results may be due to the application's provision of specific disease information and a personalized treatment plan based on the participant and other users' data. We recommend that services connected with electronic medical records target specific diseases to provide personalized health management to patients in a hospital setting.
46 CFR 45.149 - Machinery space openings.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 46 Shipping 2 2014-10-01 2014-10-01 false Machinery space openings. 45.149 Section 45.149 Shipping... Assignment § 45.149 Machinery space openings. (a) Machinery space openings in position 1 or 2 must be framed... funnel or machinery space ventilator that must be kept open for the essential operations of the ship must...
46 CFR 45.149 - Machinery space openings.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 2 2013-10-01 2013-10-01 false Machinery space openings. 45.149 Section 45.149 Shipping... Assignment § 45.149 Machinery space openings. (a) Machinery space openings in position 1 or 2 must be framed... funnel or machinery space ventilator that must be kept open for the essential operations of the ship must...
46 CFR 45.149 - Machinery space openings.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 2 2010-10-01 2010-10-01 false Machinery space openings. 45.149 Section 45.149 Shipping... Assignment § 45.149 Machinery space openings. (a) Machinery space openings in position 1 or 2 must be framed... funnel or machinery space ventilator that must be kept open for the essential operations of the ship must...
46 CFR 45.149 - Machinery space openings.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 2 2012-10-01 2012-10-01 false Machinery space openings. 45.149 Section 45.149 Shipping... Assignment § 45.149 Machinery space openings. (a) Machinery space openings in position 1 or 2 must be framed... funnel or machinery space ventilator that must be kept open for the essential operations of the ship must...
46 CFR 45.149 - Machinery space openings.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 2 2011-10-01 2011-10-01 false Machinery space openings. 45.149 Section 45.149 Shipping... Assignment § 45.149 Machinery space openings. (a) Machinery space openings in position 1 or 2 must be framed... funnel or machinery space ventilator that must be kept open for the essential operations of the ship must...
Using Open Educational Resources to Help Students Understand the Sub-Prime Lending Crisis
ERIC Educational Resources Information Center
McDowell, Evelyn A.
2010-01-01
In this paper, I describe an assignment designed to give students an intermediate level of understanding of the causes of the crisis using online educational resources widely available on the internet. I implemented the assignment in an undergraduate intermediate accounting course. Feedback from students indicate the assignment enhanced their…
Medverd, Jonathan R; Cross, Nathan M; Font, Frank; Casertano, Andrew
2013-08-01
Radiologists routinely make decisions with only limited information when assigning protocol instructions for the performance of advanced medical imaging examinations. Opportunity exists to simultaneously improve the safety, quality and efficiency of this workflow through the application of an electronic solution leveraging health system resources to provide concise, tailored information and decision support in real-time. Such a system has been developed using an open source, open standards design for use within the Veterans Health Administration. The Radiology Protocol Tool Recorder (RAPTOR) project identified key process attributes as well as inherent weaknesses of paper processes and electronic emulators of paper processes to guide the development of its optimized electronic solution. The design provides a kernel that can be expanded to create an integrated radiology environment. RAPTOR has implications relevant to the greater health care community, and serves as a case model for modernization of legacy government health information systems.
46 CFR 45.143 - Hull openings above freeboard deck.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 2 2010-10-01 2010-10-01 false Hull openings above freeboard deck. 45.143 Section 45.143 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES GREAT LAKES LOAD LINES Conditions of Assignment § 45.143 Hull openings above freeboard deck. Closures for openings above...
Specdata: Automated Analysis Software for Broadband Spectra
NASA Astrophysics Data System (ADS)
Oliveira, Jasmine N.; Martin-Drumel, Marie-Aline; McCarthy, Michael C.
2017-06-01
With the advancement of chirped-pulse techniques, broadband rotational spectra with a few tens to several hundred GHz of spectral coverage are now routinely recorded. When studying multi-component mixtures that might result, for example, with the use of an electrical discharge, lines of new chemical species are often obscured by those of known compounds, and analysis can be laborious. To address this issue, we have developed SPECdata, an open source, interactive tool which is designed to simplify and greatly accelerate the spectral analysis and discovery. Our software tool combines both automated and manual components that free the user from computation, while giving him/her considerable flexibility to assign, manipulate, interpret and export their analysis. The automated - and key - component of the new software is a database query system that rapidly assigns transitions of known species in an experimental spectrum. For each experiment, the software identifies spectral features, and subsequently assigns them to known molecules within an in-house database (Pickett .cat files, list of frequencies...), or those catalogued in Splatalogue (using automatic on-line queries). With suggested assignments, the control is then handed over to the user who can choose to accept, decline or add additional species. Data visualization, statistical information, and interactive widgets assist the user in making decisions about their data. SPECdata has several other useful features intended to improve the user experience. Exporting a full report of the analysis, or a peak file in which assigned lines are removed are among several options. A user may also save their progress to continue at another time. Additional features of SPECdata help the user to maintain and expand their database for future use. A user-friendly interface allows one to search, upload, edit or update catalog or experiment entries.
7 CFR 97.190 - When open records are available.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 7 Agriculture 3 2012-01-01 2012-01-01 false When open records are available. 97.190 Section 97.190... PLANT VARIETY AND PROTECTION Availability of Office Records § 97.190 When open records are available. Copies of records, which are open to the public and in the custody of the Office, may be examined in the...
7 CFR 97.190 - When open records are available.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 3 2010-01-01 2010-01-01 false When open records are available. 97.190 Section 97.190... PLANT VARIETY AND PROTECTION Availability of Office Records § 97.190 When open records are available. Copies of records, which are open to the public and in the custody of the Office, may be examined in the...
7 CFR 97.190 - When open records are available.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 7 Agriculture 3 2014-01-01 2014-01-01 false When open records are available. 97.190 Section 97.190... PLANT VARIETY AND PROTECTION Availability of Office Records § 97.190 When open records are available. Copies of records, which are open to the public and in the custody of the Office, may be examined in the...
7 CFR 97.190 - When open records are available.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 7 Agriculture 3 2013-01-01 2013-01-01 false When open records are available. 97.190 Section 97.190... PLANT VARIETY AND PROTECTION Availability of Office Records § 97.190 When open records are available. Copies of records, which are open to the public and in the custody of the Office, may be examined in the...
7 CFR 97.190 - When open records are available.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 7 Agriculture 3 2011-01-01 2011-01-01 false When open records are available. 97.190 Section 97.190... PLANT VARIETY AND PROTECTION Availability of Office Records § 97.190 When open records are available. Copies of records, which are open to the public and in the custody of the Office, may be examined in the...
Sullivan, Lauren A; Campbell, Vicki L; Onuma, Serene C
2010-07-15
To determine whether use of a closed urine collection system would decrease the incidence of nosocomial bacteriuria in hospitalized dogs, compared with use of an open urine collection system (used, sterile IV bags). Randomized controlled trial. 51 hospitalized dogs requiring indwelling urinary catheterization for >or= 24 hours. Dogs were randomly assigned to an open or closed urine collection system group. A standardized protocol for catheter placement and maintenance was followed for all dogs. A baseline urine sample was collected via cystocentesis for aerobic bacterial culture, with additional urine samples obtained daily from the urine collection reservoir. 27 dogs were assigned to the open urine collection system group, and 24 were assigned to the closed urine collection system group. The incidence of nosocomial bacteriuria in dogs with open urine collection systems (3/27 [11.1%]) was not significantly different from incidence in dogs with closed urine collection systems (2/24 [8.3%]). Median duration of catheterization was 2 days for dogs in both groups; the range was 1 to 7 days for dogs in the open group and 1 to 5 days for dogs in the closed group. Results suggested that for dogs requiring short-term indwelling urinary catheterization, the type of urine collection system (open vs closed) was not associated with likelihood of developing nosocomial bacteriuria. Use of a strict protocol for urinary catheter placement and maintenance was likely key in the low incidence of nosocomial bacteriuria in the present study.
ERIC Educational Resources Information Center
Corbi, Alberto; Burgos, Daniel
2017-01-01
This paper presents how virtual containers enhance the implementation of STEAM (science, technology, engineering, arts, and math) subjects as Open Educational Resources (OER). The publication initially summarizes the limitations of delivering open rich learning contents and corresponding assignments to students in college level STEAM areas. The…
Etaee, Farshid; Asadbegi, Masoumeh; Taslimi, Zahra; Shahidi, Siamak; Sarihi, Abdolrahman; Soleimani Asl, Sara; Komaki, Alireza
2017-08-10
Methamphetamine (Meth) abuse and dependence are major global problems. Most of previous studies showed that Meth is anxiogenic. While buprenorphine (Bup) is used to treat anxiety-related behaviors, the effects of Meth in combination with Bup on anxiety-like behavior are unclear. In this study, we examined the effects of these drugs on anxiety-like behavior with the elevated plus maze (EPM) and open field (OF) tests, which are widely used to assess anxiety-like behavior in small rodents. Forty male Wistar rats were divided into four groups: sham, Meth, Bup, and Bup+Meth. The groups were administered their assigned treatments for 7days. The time spent in the open arms, and number of total entries into the arms (total activity) in the EPM were recorded. In addition, locomotor activity and number of entrances into the center area in the OF were recorded. The 7-day administration of Meth or Bup increased open arm exploration in the EPM. In contrast, the combined administration of Bup and Meth had the opposite effects. In addition, Meth and Bup had no effects on total and locomotor activity. Furthermore, the rats in the Meth and Bup groups spent more time in the center of the OF, while the group given both Bup and Meth spent less time in the center of the OF. The administration of Meth and Bup alone was anxiolytic in rats, whereas the coadministration of Bup and Meth was anxiogenic. Copyright © 2017 Elsevier B.V. All rights reserved.
Prioritized Contact Transport Stream
NASA Technical Reports Server (NTRS)
Hunt, Walter Lee, Jr. (Inventor)
2015-01-01
A detection process, contact recognition process, classification process, and identification process are applied to raw sensor data to produce an identified contact record set containing one or more identified contact records. A prioritization process is applied to the identified contact record set to assign a contact priority to each contact record in the identified contact record set. Data are removed from the contact records in the identified contact record set based on the contact priorities assigned to those contact records. A first contact stream is produced from the resulting contact records. The first contact stream is streamed in a contact transport stream. The contact transport stream may include and stream additional contact streams. The contact transport stream may be varied dynamically over time based on parameters such as available bandwidth, contact priority, presence/absence of contacts, system state, and configuration parameters.
Data Publication: A Partnership between Scientists, Data Managers and Librarians
NASA Astrophysics Data System (ADS)
Raymond, L.; Chandler, C.; Lowry, R.; Urban, E.; Moncoiffe, G.; Pissierssens, P.; Norton, C.; Miller, H.
2012-04-01
Current literature on the topic of data publication suggests that success is best achieved when there is a partnership between scientists, data managers, and librarians. The Marine Biological Laboratory/Woods Hole Oceanographic Institution (MBLWHOI) Library and the Biological and Chemical Oceanography Data Management Office (BCO-DMO) have developed tools and processes to automate the ingestion of metadata from BCO-DMO for deposit with datasets into the Institutional Repository (IR) Woods Hole Open Access Server (WHOAS). The system also incorporates functionality for BCO-DMO to request a Digital Object Identifier (DOI) from the Library. This partnership allows the Library to work with a trusted data repository to ensure high quality data while the data repository utilizes library services and is assured of a permanent archive of the copy of the data extracted from the repository database. The assignment of persistent identifiers enables accurate data citation. The Library can assign a DOI to appropriate datasets deposited in WHOAS. A primary activity is working with authors to deposit datasets associated with published articles. The DOI would ideally be assigned before submission and be included in the published paper so readers can link directly to the dataset, but DOIs are also being assigned to datasets related to articles after publication. WHOAS metadata records link the article to the datasets and the datasets to the article. The assignment of DOIs has enabled another important collaboration with Elsevier, publisher of educational and professional science journals. Elsevier can now link from articles in the Science Direct database to the datasets available from WHOAS that are related to that article. The data associated with the article are freely available from WHOAS and accompanied by a Dublin Core metadata record. In addition, the Library has worked with researchers to deposit datasets in WHOAS that are not appropriate for national, international, or domain specific data repositories. These datasets currently include audio, text and image files. This research is being conducted by a team of librarians, data managers and scientists that are collaborating with representatives from the Scientific Committee on Oceanic Research (SCOR) and the International Oceanographic Data and Information Exchange (IODE) of the Intergovernmental Oceanographic Commission (IOC). The goal is to identify best practices for tracking data provenance and clearly attributing credit to data collectors/providers.
PRISM 8 degrees X 10 degrees North Hemisphere paleoclimate reconstruction; digital data
Barron, John A.; Cronin, Thomas M.; Dowsett, Harry J.; Fleming, Farley R.; Holtz, Thomas R.; Ishman, Scott E.; Poore, Richard Z.; Thompson, Robert S.; Willard, Debra A.
1994-01-01
The PRISM 8?x10? data set represents several years of investigation by PRISM (Pliocene Research, Interpretation, and Synoptic Mapping) Project members. One of the goals of PRISM is to produce time-slice reconstructions of intervals of warmer than modern climate within the Pliocene Epoch. The first of these was chosen to be at 3.0 Ma (time scale of Berggren et al., 1985) and is published in Global and Planetary Change (Dowsett et al., 1994). This document contains the actual data sets and a brief explanation of how they were constructed. For paleoenvironmental interpretations and discussion of each data set, see Dowsett et al., in press. The data sets includes sea level, land ice distribution, vegetation or land cover, sea surface temperature and sea-ice cover matrices. This reconstruction of Middle Pliocene climate is organized as a series of datasets representing different environmental attributes. The data sets are designed for use with the GISS Model II atmospheric general circulation model (GCM) using an 8?x10? resolution (Hansen et al., 1983). The first step in documenting the Pliocene climate involves assigning an appropriate fraction of land versus ocean to each grid box. Following grid cell by grid cell, land versus ocean allocations, winter and summer sea ice coverage of ocean areas are assigned and then winter and summer sea surface temperatures are assigned to open ocean areas. Average land ice cover is recorded for land areas and then land areas not covered by ice are assigned proportions of six vegetation or land cover categories modified from Hansen et al. (1983).
Adelman, Jason S; Berger, Matthew A; Rai, Amisha; Galanter, William L; Lambert, Bruce L; Schiff, Gordon D; Vawdrey, David K; Green, Robert A; Salmasian, Hojjat; Koppel, Ross; Schechter, Clyde B; Applebaum, Jo R; Southern, William N
2017-09-01
To reduce the risk of wrong-patient errors, safety experts recommend limiting the number of patient records providers can open at once in electronic health records (EHRs). However, it is unknown whether health care organizations follow this recommendation or what rationales drive their decisions. To address this gap, we conducted an electronic survey via 2 national listservs. Among 167 inpatient and outpatient study facilities using EHR systems designed to open multiple records at once, 44.3% were configured to allow ≥3 records open at once (unrestricted), 38.3% allowed only 1 record open (restricted), and 17.4% allowed 2 records open (hedged). Decision-making centered on efforts to balance safety and efficiency, but there was disagreement among organizations about how to achieve that balance. Results demonstrate no consensus on the number of records to be allowed open at once in EHRs. Rigorous studies are needed to determine the optimal number of records that balances safety and efficiency. © The Author 2017. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
AUTOBA: automation of backbone assignment from HN(C)N suite of experiments.
Borkar, Aditi; Kumar, Dinesh; Hosur, Ramakrishna V
2011-07-01
Development of efficient strategies and automation represent important milestones of progress in rapid structure determination efforts in proteomics research. In this context, we present here an efficient algorithm named as AUTOBA (Automatic Backbone Assignment) designed to automate the assignment protocol based on HN(C)N suite of experiments. Depending upon the spectral dispersion, the user can record 2D or 3D versions of the experiments for assignment. The algorithm uses as inputs: (i) protein primary sequence and (ii) peak-lists from user defined HN(C)N suite of experiments. In the end, one gets H(N), (15)N, C(α) and C' assignments (in common BMRB format) for the individual residues along the polypeptide chain. The success of the algorithm has been demonstrated, not only with experimental spectra recorded on two small globular proteins: ubiquitin (76 aa) and M-crystallin (85 aa), but also with simulated spectra of 27 other proteins using assignment data from the BMRB.
Lorgelly, Paula K.; Dias, Joseph J.; Bradley, Mary J.; Burke, Frank D.
2005-01-01
OBJECTIVE: There is insufficient evidence regarding the clinical and cost-effectiveness of surgical interventions for carpal tunnel syndrome. This study evaluates the cost, effectiveness and cost-effectiveness of minimally invasive surgery compared with conventional open surgery. PATIENTS AND METHODS: 194 sufferers (208 hands) of carpal tunnel syndrome were randomly assigned to each treatment option. A self-administered questionnaire assessed the severity of patients' symptoms and functional status pre- and postoperatively. Treatment costs were estimated from resource use and hospital financial data. RESULTS: Minimally invasive carpal tunnel decompression is marginally more effective than open surgery in terms of functional status, but not significantly so. Little improvement in symptom severity was recorded for either intervention. Minimally invasive surgery was found to be significantly more costly than open surgery. The incremental cost effectiveness ratio for functional status was estimated to be 197 UK pounds, such that a one percentage point improvement in functioning costs 197 UK pounds when using the minimally invasive technique. CONCLUSIONS: Minimally invasive carpal tunnel decompression appears to be more effective but more costly. Initial analysis suggests that the additional expense for such a small improvement in function and no improvement in symptoms would not be regarded as value-for-money, such that minimally invasive carpal tunnel release is unlikely to be considered a cost-effective alternative to the traditional open surgery procedure. PMID:15720906
Aguiar, Paulo; Mendonça, Luís; Galhardo, Vasco
2007-10-15
Operant animal behavioral tests require the interaction of the subject with sensors and actuators distributed in the experimental environment of the arena. In order to provide user independent reliable results and versatile control of these devices it is vital to use an automated control system. Commercial systems for control of animal mazes are usually based in software implementations that restrict their application to the proprietary hardware of the vendor. In this paper we present OpenControl: an opensource Visual Basic software that permits a Windows-based computer to function as a system to run fully automated behavioral experiments. OpenControl integrates video-tracking of the animal, definition of zones from the video signal for real-time assignment of animal position in the maze, control of the maze actuators from either hardware sensors or from the online video tracking, and recording of experimental data. Bidirectional communication with the maze hardware is achieved through the parallel-port interface, without the need for expensive AD-DA cards, while video tracking is attained using an inexpensive Firewire digital camera. OpenControl Visual Basic code is structurally general and versatile allowing it to be easily modified or extended to fulfill specific experimental protocols and custom hardware configurations. The Visual Basic environment was chosen in order to allow experimenters to easily adapt the code and expand it at their own needs.
14 CFR 385.20 - Authority of the Inspector General.
Code of Federal Regulations, 2010 CFR
2010-01-01
... PROCEEDINGS) ORGANIZATION STAFF ASSIGNMENTS AND REVIEW OF ACTION UNDER ASSIGNMENTS Assignment of Functions to... examinations of carrier facilities, operations, and accounting and statistical records. (b)(1) For accounting... statements necessary to an explanation of any carrier accounting practice. [Docket No. T-1, 49 FR 50985, Dec...
ERIC Educational Resources Information Center
Ofoha, D.
2012-01-01
The success of any open and distance learning (ODL) programme depends on how well it is evaluated. In the National Open University of Nigeria (NOUN), students are assessed and evaluated through continuous assessment as well as end of semester examinations. This paper focuses on Tutor Marked Assignment (TMA), which forms part of continuous…
21 CFR 11.30 - Controls for open systems.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Controls for open systems. 11.30 Section 11.30... RECORDS; ELECTRONIC SIGNATURES Electronic Records § 11.30 Controls for open systems. Persons who use open systems to create, modify, maintain, or transmit electronic records shall employ procedures and controls...
21 CFR 11.30 - Controls for open systems.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Controls for open systems. 11.30 Section 11.30... RECORDS; ELECTRONIC SIGNATURES Electronic Records § 11.30 Controls for open systems. Persons who use open systems to create, modify, maintain, or transmit electronic records shall employ procedures and controls...
21 CFR 11.30 - Controls for open systems.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Controls for open systems. 11.30 Section 11.30... RECORDS; ELECTRONIC SIGNATURES Electronic Records § 11.30 Controls for open systems. Persons who use open systems to create, modify, maintain, or transmit electronic records shall employ procedures and controls...
21 CFR 11.30 - Controls for open systems.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Controls for open systems. 11.30 Section 11.30... RECORDS; ELECTRONIC SIGNATURES Electronic Records § 11.30 Controls for open systems. Persons who use open systems to create, modify, maintain, or transmit electronic records shall employ procedures and controls...
21 CFR 11.30 - Controls for open systems.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Controls for open systems. 11.30 Section 11.30... RECORDS; ELECTRONIC SIGNATURES Electronic Records § 11.30 Controls for open systems. Persons who use open systems to create, modify, maintain, or transmit electronic records shall employ procedures and controls...
Eardley, Debra L; Krumwiede, Kelly A; Secginli, Selda; Garner, Linda; DeBlieck, Conni; Cosansu, Gulhan; Nahcivan, Nursen O
2018-06-01
Advancements in healthcare systems include adoption of health information technology to ensure healthcare quality. Educators are challenged to determine strategies to integrate health information technology into nursing curricula for building a nursing workforce competent with electronic health records, standardized terminology, evidence-based practice, and evaluation. Nursing informatics, a growing specialty field, comprises health information technology relative to the profession of nursing. It is essential to integrate nursing informatics across nursing curricula to effectively position competent graduates in technology-laden healthcare environments. Nurse scholars developed and evaluated a nursing informatics case study assignment used in undergraduate level public health nursing courses. The assignment included an unfolding scenario followed by electronic health record charting using standardized terminology to guide the nursing process. The assignment was delivered either online or in class. Seventy-two undergraduate students completed the assignment and a posttest. Fifty-one students completed a satisfaction survey. Results indicated that students who completed the assignment online demonstrated a higher level of content mastery than those who completed the assignment in class. Content mastery was based on posttest results, which evaluated students' electronic health record charting for the nursing assessment, evidence-based interventions, and evaluations. This innovative approach may be valuable to educators in response to the National Academy of Sciences recommendations for healthcare education reform.
46 CFR 45.135 - Hull openings at or below freeboard deck.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 2 2010-10-01 2010-10-01 false Hull openings at or below freeboard deck. 45.135 Section 45.135 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES GREAT LAKES LOAD LINES Conditions of Assignment § 45.135 Hull openings at or below freeboard deck. Closures for hull...
46 CFR 42.15-35 - Machinery space openings.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 2 2013-10-01 2013-10-01 false Machinery space openings. 42.15-35 Section 42.15-35... BY SEA Conditions of Assignment of Freeboard § 42.15-35 Machinery space openings. (a) Machinery space..., funnel, or machinery space ventilators in an exposed position on the freeboard or superstructure deck...
46 CFR 42.15-35 - Machinery space openings.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 2 2011-10-01 2011-10-01 false Machinery space openings. 42.15-35 Section 42.15-35... BY SEA Conditions of Assignment of Freeboard § 42.15-35 Machinery space openings. (a) Machinery space..., funnel, or machinery space ventilators in an exposed position on the freeboard or superstructure deck...
46 CFR 42.15-35 - Machinery space openings.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 46 Shipping 2 2014-10-01 2014-10-01 false Machinery space openings. 42.15-35 Section 42.15-35... BY SEA Conditions of Assignment of Freeboard § 42.15-35 Machinery space openings. (a) Machinery space..., funnel, or machinery space ventilators in an exposed position on the freeboard or superstructure deck...
46 CFR 42.15-35 - Machinery space openings.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 2 2010-10-01 2010-10-01 false Machinery space openings. 42.15-35 Section 42.15-35... BY SEA Conditions of Assignment of Freeboard § 42.15-35 Machinery space openings. (a) Machinery space..., funnel, or machinery space ventilators in an exposed position on the freeboard or superstructure deck...
46 CFR 42.15-35 - Machinery space openings.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 2 2012-10-01 2012-10-01 false Machinery space openings. 42.15-35 Section 42.15-35... BY SEA Conditions of Assignment of Freeboard § 42.15-35 Machinery space openings. (a) Machinery space..., funnel, or machinery space ventilators in an exposed position on the freeboard or superstructure deck...
NASA Astrophysics Data System (ADS)
Copas, K.; Legind, J. K.; Hahn, A.; Braak, K.; Høftt, M.; Noesgaard, D.; Robertson, T.; Méndez Hernández, F.; Schigel, D.; Ko, C.
2017-12-01
GBIF—the Global Biodiversity Information Facility—has recently demonstrated a system that tracks publications back to individual datasets, giving data providers demonstrable evidence of the benefit and utility of sharing data to support an array of scholarly topics and practical applications. GBIF is an open-data network and research infrastructure funded by the world's governments. Its community consists of more than 90 formal participants and almost 1,000 data-publishing institutions, which currently make tens of thousands of datasets containing nearly 800 million species occurrence records freely and publicly available for discovery, use and reuse across a wide range of biodiversity-related research and policy investigations. Starting in 2015 with the help of DataONE, GBIF introduced DOIs as persistent identifiers for the datasets shared through its network. This enhancement soon extended to the assignment of DOIs to user downloads from GBIF.org, which typically filter the available records with a variety of taxonomic, geographic, temporal and other search terms. Despite the lack of widely accepted standards for citing data among researchers and publications, this technical infrastructure is beginning to take hold and support open, transparent, persistent and repeatable use and reuse of species occurrence data. These `download DOIs' provide canonical references for the search results researchers process and use in peer-reviewed articles—a practice GBIF encourages by confirming new DOIs with each download and offering guidelines on citation. GBIF has recently started linking these citation results back to dataset and publisher pages, offering more consistent, traceable evidence of the value of sharing data to support others' research. GBIF's experience may be a useful model for other repositories to follow.
Dating the Vostok ice core record by importing the Devils Hole chronology
Landwehr, J.M.; Winograd, I.J.
2001-01-01
The development of an accurate chronology for the Vostok record continues to be an open research question because these invaluable ice cores cannot be dated directly. Depth-to-age relationships have been developed using many different approaches, but published age estimates are inconsistent, even for major paleoclimatic events. We have developed a chronology for the Vostok deuterium paleotemperature record using a simple and objective algorithm to transfer ages of major paleoclimatic events from the radiometrically dated 500,000-year ??18O-paleotemperature record from Devils Hole, Nevada. The method is based only on a strong inference that major shifts in paleotemperature recorded at both locations occurred synchronously, consistent with an atmospheric teleconnection. The derived depth-to-age relationship conforms with the physics of ice compaction, and internally produces ages for climatic events 5.4 and 11.24 which are consistent with the externally assigned ages that the Vostok team needed to assume in order to derive their most recent chronology, GT4. Indeed, the resulting V-DH chronology is highly correlated with GT4 because of the unexpected correspondence even in the timing of second-order climatic events that were not constrained by the algorithm. Furthermore, the algorithm developed herein is not specific to this problem; rather, the procedure can be used whenever two paleoclimate records are proxies for the same physical phenomenon, and paleoclimatic conditions forcing the two records can be considered to have occurred contemporaneously. The ability of the algorithm to date the East Antarctic Dome Fuji core is also demonstrated.
Sensitivity and Specificity of Eustachian Tube Function Tests in Adults
Doyle, William J.; Swarts, J. Douglas; Banks, Julianne; Casselbrant, Margaretha L; Mandel, Ellen M; Alper, Cuneyt M.
2013-01-01
Objective Determine if Eustachian Tube (ET) function (ETF) tests can identify ears with physician-diagnosed ET dysfunction (ETD) in a mixed population at high sensitivity and specificity and define the inter-relatedness of ETF test parameters. Methods ETF was evaluated using the Forced-Response, Inflation-Deflation, Valsalva and Sniffing tests in 15 control ears of adult subjects after unilateral myringotomy (Group I) and in 23 ears of 19 adult subjects with ventilation tubes inserted for ETD (Group II). Data were analyzed using logistic regression including each parameter independently and then a step-down Discriminant Analysis including all ETF test parameters to predict group assignment. Factor Analysis operating over all parameters was used to explore relatedness. Results The Discriminant Analysis identified 4 ETF test parameters (Valsalva, ET opening pressure, dilatory efficiency and % positive pressure equilibrated) that together correctly assigned ears to Group II at a sensitivity of 95% and a specificity of 83%. Individual parameters representing the efficiency of ET opening during swallowing showed moderately accurate assignments of ears to their respective groups. Three factors captured approximately 98% of the variance among parameters, the first had negative loadings of the ETF structural parameters, the second had positive loadings of the muscle-assisted ET opening parameters and the third had negative loadings of the muscle-assisted ET opening parameters and positive loadings of the structural parameters. Discussion These results show that ETF tests can correctly assign individual ears to physician-diagnosed ETD with high sensitivity and specificity and that ETF test parameters can be grouped into structural-functional categories. PMID:23868429
Using Popular Culture in Developmental Writing
ERIC Educational Resources Information Center
Barnes, Sharon L.
2006-01-01
Using popular culture in my developmental writing course has prompted me to reconsider what it means to create successful developmental writing assignments. Having slipped into the questionable habit of assuming that removing complexity makes an assignment appropriate for developing writers, I pared down a fairly open-ended "media…
36 CFR 292.22 - Land category assignments.
Code of Federal Regulations, 2010 CFR
2010-07-01
... availability of this map or maps in the local newspapers of record. (b) Changes in land category assignment.../grazing land so long as the intended use or development is consistent with the standards in § 292.23 and... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Land category assignments...
NHEXAS PHASE I ARIZONA STUDY--STANDARD OPERATING PROCEDURE FOR HHID AND IRN ASSIGNMENT (UA-F-1.0)
The purpose of this SOP is to outline HHID and IRN assignment during the Arizona NHEXAS project and the "Border" study. Keywords: field; records; HHID and IRN Assignment.
The National Human Exposure Assessment Survey (NHEXAS) is a federal interagency research effort coordinated...
Using Self-Recording, Evaluation, and Graphing to Increase Completion of Homework Assignments.
ERIC Educational Resources Information Center
Trammel, Diana Lynn; And Others
1994-01-01
Self-monitoring procedures were effective in increasing the number of daily homework assignments completed by eight secondary level students with learning disabilities. A daily listing of all assignments given by regular classroom teachers was used. Goal setting and self-graphing of data appeared to increase self-monitoring effectiveness. (DB)
12 CFR 309.5 - Procedures for requesting records.
Code of Federal Regulations, 2011 CFR
2011-01-01
..., microfilm, audiovisual records, or machine readable records (e.g., magnetic tape or computer disk). (4... processing. A requester may contact the FOIA/PA Group to learn whether a particular request has been assigned...
12 CFR 309.5 - Procedures for requesting records.
Code of Federal Regulations, 2010 CFR
2010-01-01
..., microfilm, audiovisual records, or machine readable records (e.g., magnetic tape or computer disk). (4... processing. A requester may contact the FOIA/PA Group to learn whether a particular request has been assigned...
12 CFR 309.5 - Procedures for requesting records.
Code of Federal Regulations, 2012 CFR
2012-01-01
..., microfilm, audiovisual records, or machine readable records (e.g., magnetic tape or computer disk). (4... processing. A requester may contact the FOIA/PA Group to learn whether a particular request has been assigned...
12 CFR 309.5 - Procedures for requesting records.
Code of Federal Regulations, 2013 CFR
2013-01-01
..., microfilm, audiovisual records, or machine readable records (e.g., magnetic tape or computer disk). (4... processing. A requester may contact the FOIA/PA Group to learn whether a particular request has been assigned...
12 CFR 309.5 - Procedures for requesting records.
Code of Federal Regulations, 2014 CFR
2014-01-01
..., microfilm, audiovisual records, or machine readable records (e.g., magnetic tape or computer disk). (4... processing. A requester may contact the FOIA/PA Group to learn whether a particular request has been assigned...
Sensitivity and specificity of eustachian tube function tests in adults.
Doyle, William J; Swarts, J Douglas; Banks, Julianne; Casselbrant, Margaretha L; Mandel, Ellen M; Alper, Cuneyt M
2013-07-01
The study demonstrates the utility of eustachian tube (ET) function (ETF) test results for accurately assigning ears to disease state. To determine if ETF tests can identify ears with physician-diagnosed ET dysfunction (ETD) in a mixed population at high sensitivity and specificity and to define the interrelatedness of ETF test parameters. Through use of the forced-response, inflation-deflation, Valsalva, and sniffing tests, ETF was evaluated in 15 control ears of adult subjects after unilateral myringotomy (group 1) and in 23 ears of 19 adult subjects with ventilation tubes inserted for ETD (group 2). Data were analyzed using logistic regression including each parameter independently and then a step-down discriminant analysis including all ETF test parameters to predict group assignment. Factor analysis operating over all parameters was used to explore relatedness. ETF testing. ETF parameters for the forced response, inflation-deflation, Valsalva, and sniffing tests measured in 15 control ears of adult subjects after unilateral myringotomy (group 1) and in 23 ears of 19 adult subjects with ventilation tubes inserted for ETD (group 2). The discriminant analysis identified 4 ETF test parameters (Valsalva, ET opening pressure, dilatory efficiency, and percentage of positive pressure equilibrated) that together correctly assigned ears to group 2 at a sensitivity of 95% and a specificity of 83%. Individual parameters representing the efficiency of ET opening during swallowing showed moderately accurate assignments of ears to their respective groups. Three factors captured approximately 98% of the variance among parameters: the first had negative loadings of the ETF structural parameters; the second had positive loadings of the muscle-assisted ET opening parameters; and the third had negative loadings of the muscle-assisted ET opening parameters and positive loadings of the structural parameters. These results show that ETF tests can correctly assign individual ears to physician-diagnosed ETD with high sensitivity and specificity and that ETF test parameters can be grouped into structural-functional categories.
Exploring the Contribution of Extra Credit in Marketing Education
ERIC Educational Resources Information Center
Elbeck, Matt; DeLong, Deborah
2015-01-01
This study advances the literature on the incidence, attitudes and motivations to complete extra credit assignments. Behavioral feedback from 59 marketing instructors and 43 Principles of Marketing students aligned with reported incidence rates of offering and completing extra credit assignments, respectively. This was followed with open-ended…
77 FR 31400 - Nixon Presidential Historical Materials: Opening of Materials
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-25
... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Nixon Presidential Historical Materials: Opening of Materials AGENCY: National Archives and Records Administration. ACTION: Notice of Opening of Additional... by the Richard Nixon Presidential Library and Museum, a division of the National Archives and Records...
77 FR 58179 - Nixon Presidential Historical Materials: Opening of Materials
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-19
... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Nixon Presidential Historical Materials: Opening of Materials AGENCY: National Archives and Records Administration ACTION: Notice of opening of additional... by the Richard Nixon Presidential Library and Museum, a division of the National Archives and Records...
76 FR 27092 - Nixon Presidential Historical Materials: Opening of Materials
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-10
... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Nixon Presidential Historical Materials: Opening of Materials AGENCY: National Archives and Records Administration. ACTION: Notice of opening of additional... by the Richard Nixon Presidential Library and Museum, a division of the National Archives and Records...
75 FR 68384 - Nixon Presidential Historical Materials: Opening of Materials
Federal Register 2010, 2011, 2012, 2013, 2014
2010-11-05
... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Nixon Presidential Historical Materials: Opening of Materials AGENCY: National Archives and Records Administration. ACTION: Notice of Opening of Additional... by the Richard Nixon Presidential Library and Museum, a division of the National Archives and Records...
Dinosaur origin of egg color: oviraptors laid blue-green eggs
Yang, Tzu-Ruei; Sander, Philipp N.; Schneider, Marion; Engeser, Marianne; Kath-Schorr, Stephanie; Müller, Christa E.; Sander, P. Martin
2017-01-01
Protoporphyrin (PP) and biliverdin (BV) give rise to the enormous diversity in avian egg coloration. Egg color serves several ecological purposes, including post-mating signaling and camouflage. Egg camouflage represents a major character of open-nesting birds which accomplish protection of their unhatched offspring against visually oriented predators by cryptic egg coloration. Cryptic coloration evolved to match the predominant shades of color found in the nesting environment. Such a selection pressure for the evolution of colored or cryptic eggs should be present in all open nesting birds and relatives. Many birds are open-nesting, but protect their eggs by continuous brooding, and thus exhibit no or minimal eggshell pigmentation. Their closest extant relatives, crocodiles, protect their eggs by burial and have unpigmented eggs. This phylogenetic pattern led to the assumption that colored eggs evolved within crown birds. The mosaic evolution of supposedly avian traits in non-avian theropod dinosaurs, however, such as the supposed evolution of partially open nesting behavior in oviraptorids, argues against this long-established theory. Using a double-checking liquid chromatography ESI-Q-TOF mass spectrometry routine, we traced the origin of colored eggs to their non-avian dinosaur ancestors by providing the first record of the avian eggshell pigments protoporphyrin and biliverdin in the eggshells of Late Cretaceous oviraptorid dinosaurs. The eggshell parataxon Macroolithus yaotunensis can be assigned to the oviraptor Heyuannia huangi based on exceptionally preserved, late developmental stage embryo remains. The analyzed eggshells are from three Late Cretaceous fluvial deposits ranging from eastern to southernmost China. Reevaluation of these taphonomic settings, and a consideration of patterns in the porosity of completely preserved eggs support an at least partially open nesting behavior for oviraptorosaurs. Such a nest arrangement corresponds with our reconstruction of blue-green eggs for oviraptors. According to the sexual signaling hypothesis, the reconstructed blue-green eggs support the origin of previously hypothesized avian paternal care in oviraptorid dinosaurs. Preserved dinosaur egg color not only pushes the current limits of the vertebrate molecular and associated soft tissue fossil record, but also provides a perspective on the potential application of this unexplored paleontological resource. PMID:28875070
Dinosaur origin of egg color: oviraptors laid blue-green eggs.
Wiemann, Jasmina; Yang, Tzu-Ruei; Sander, Philipp N; Schneider, Marion; Engeser, Marianne; Kath-Schorr, Stephanie; Müller, Christa E; Sander, P Martin
2017-01-01
Protoporphyrin (PP) and biliverdin (BV) give rise to the enormous diversity in avian egg coloration. Egg color serves several ecological purposes, including post-mating signaling and camouflage. Egg camouflage represents a major character of open-nesting birds which accomplish protection of their unhatched offspring against visually oriented predators by cryptic egg coloration. Cryptic coloration evolved to match the predominant shades of color found in the nesting environment. Such a selection pressure for the evolution of colored or cryptic eggs should be present in all open nesting birds and relatives. Many birds are open-nesting, but protect their eggs by continuous brooding, and thus exhibit no or minimal eggshell pigmentation. Their closest extant relatives, crocodiles, protect their eggs by burial and have unpigmented eggs. This phylogenetic pattern led to the assumption that colored eggs evolved within crown birds. The mosaic evolution of supposedly avian traits in non-avian theropod dinosaurs, however, such as the supposed evolution of partially open nesting behavior in oviraptorids, argues against this long-established theory. Using a double-checking liquid chromatography ESI-Q-TOF mass spectrometry routine, we traced the origin of colored eggs to their non-avian dinosaur ancestors by providing the first record of the avian eggshell pigments protoporphyrin and biliverdin in the eggshells of Late Cretaceous oviraptorid dinosaurs. The eggshell parataxon Macroolithus yaotunensis can be assigned to the oviraptor Heyuannia huangi based on exceptionally preserved, late developmental stage embryo remains. The analyzed eggshells are from three Late Cretaceous fluvial deposits ranging from eastern to southernmost China. Reevaluation of these taphonomic settings, and a consideration of patterns in the porosity of completely preserved eggs support an at least partially open nesting behavior for oviraptorosaurs. Such a nest arrangement corresponds with our reconstruction of blue-green eggs for oviraptors. According to the sexual signaling hypothesis, the reconstructed blue-green eggs support the origin of previously hypothesized avian paternal care in oviraptorid dinosaurs. Preserved dinosaur egg color not only pushes the current limits of the vertebrate molecular and associated soft tissue fossil record, but also provides a perspective on the potential application of this unexplored paleontological resource.
Rule-based deduplication of article records from bibliographic databases.
Jiang, Yu; Lin, Can; Meng, Weiyi; Yu, Clement; Cohen, Aaron M; Smalheiser, Neil R
2014-01-01
We recently designed and deployed a metasearch engine, Metta, that sends queries and retrieves search results from five leading biomedical databases: PubMed, EMBASE, CINAHL, PsycINFO and the Cochrane Central Register of Controlled Trials. Because many articles are indexed in more than one of these databases, it is desirable to deduplicate the retrieved article records. This is not a trivial problem because data fields contain a lot of missing and erroneous entries, and because certain types of information are recorded differently (and inconsistently) in the different databases. The present report describes our rule-based method for deduplicating article records across databases and includes an open-source script module that can be deployed freely. Metta was designed to satisfy the particular needs of people who are writing systematic reviews in evidence-based medicine. These users want the highest possible recall in retrieval, so it is important to err on the side of not deduplicating any records that refer to distinct articles, and it is important to perform deduplication online in real time. Our deduplication module is designed with these constraints in mind. Articles that share the same publication year are compared sequentially on parameters including PubMed ID number, digital object identifier, journal name, article title and author list, using text approximation techniques. In a review of Metta searches carried out by public users, we found that the deduplication module was more effective at identifying duplicates than EndNote without making any erroneous assignments.
Rule-based deduplication of article records from bibliographic databases
Jiang, Yu; Lin, Can; Meng, Weiyi; Yu, Clement; Cohen, Aaron M.; Smalheiser, Neil R.
2014-01-01
We recently designed and deployed a metasearch engine, Metta, that sends queries and retrieves search results from five leading biomedical databases: PubMed, EMBASE, CINAHL, PsycINFO and the Cochrane Central Register of Controlled Trials. Because many articles are indexed in more than one of these databases, it is desirable to deduplicate the retrieved article records. This is not a trivial problem because data fields contain a lot of missing and erroneous entries, and because certain types of information are recorded differently (and inconsistently) in the different databases. The present report describes our rule-based method for deduplicating article records across databases and includes an open-source script module that can be deployed freely. Metta was designed to satisfy the particular needs of people who are writing systematic reviews in evidence-based medicine. These users want the highest possible recall in retrieval, so it is important to err on the side of not deduplicating any records that refer to distinct articles, and it is important to perform deduplication online in real time. Our deduplication module is designed with these constraints in mind. Articles that share the same publication year are compared sequentially on parameters including PubMed ID number, digital object identifier, journal name, article title and author list, using text approximation techniques. In a review of Metta searches carried out by public users, we found that the deduplication module was more effective at identifying duplicates than EndNote without making any erroneous assignments. PMID:24434031
UV absorption spectrum of allene radical cations in solid argon
NASA Astrophysics Data System (ADS)
Chin, Chih-Hao; Lin, Meng-Yeh; Huang, Tzu-Ping; Wu, Yu-Jong
2018-05-01
Electron bombardment during deposition of an Ar matrix containing a small proportion of allene generated allene cations. Further irradiation of the matrix sample at 385 nm destroyed the allene cations and formed propyne cations in solid Ar. Both cations were identified according to previously reported IR absorption bands. Using a similar technique, we recorded the ultraviolet absorption spectrum of allene cations in solid Ar. The vibrationally resolved progression recorded in the range of 266-237 nm with intervals of about 800 cm-1 was assigned to the A2E ← X2E transition of allene cations, and the broad continuum absorption recorded in the region of 229-214 nm was assigned to their B2A1 ← X2E transition. These assignments were made based on the observed photolytic behavior of the progressions and the vertical excitation energies and oscillator strengths calculated using time-dependent density functional theory.
Data Quality Assurance and Provenance Tracking in ICOADS Release 3.0
NASA Astrophysics Data System (ADS)
Cram, T.; Worley, S. J.; Ji, Z.; Schuster, D.
2017-12-01
The International Comprehensive Ocean-Atmosphere Data Set (ICOADS) Release 3.0 (R3.0) is the world's most extensive collection of global surface marine meteorological in situ observational data. Managed under an international partnership, it contains over 455 million unique multi-parameter records, dates back to 1662, and is updated monthly in near real-time. It is a foundational dataset for weather and climate research that has been used by thousands of users. By using rigorous data preparation methods, new IT infrastructure, and International Maritime Meteorological Archive (IMMA) format enhancements, ICOADS R3.0 is exemplary in data quality assurance, provenance tracking, and capturing user feedback. The features in this data lifecycle management will be presented and include, but are not limited to, written data translation specification for each data source being added to ICOADS, assignment of data source identification parameters, attachment of the original data in the IMMA format to support future re-evaluation if necessary, permanently assigned unique identification on every record making data development and community collaborations easily possible using a relational database infrastructure, and extensible capacity of the IMMA format to augment the data richness beyond the primary scope of marine surface data. Some recent augmentations are more completely specified ocean observations from profiling observing systems, feedback data submitted by the atmospheric and oceanographic reanalysis providers, higher quality edited cloud reports, and community provided data value adjustments with uncertainty estimates. Highlights covering these ICOADS value-added features will be explained and the open free access from NCAR will be briefly described.
75 FR 30863 - Nixon Presidential Historical Materials: Opening of Materials
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-02
... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Nixon Presidential Historical Materials: Opening of Materials AGENCY: National Archives and Records Administration. ACTION: Notice of opening of additional materials. SUMMARY: This notice announces the opening of additional Nixon Presidential Historical Materials...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-22
... DEPARTMENT OF LABOR Mine Safety and Health Administration Proposed Extension of Existing Information Collection; Mine Mapping and Records of Opening, Closing, and Reopening of Mines (Formerly, Record of Mine Closures, Opening & Reopening of Mines) AGENCY: Mine Safety and Health Administration, Labor...
20 CFR 404.1220 - Identification numbers.
Code of Federal Regulations, 2010 CFR
2010-04-01
... numbers for payroll record units. SSA assigns, at a State's request, unit numbers to payroll record units within a State or political subdivision. When a State requests separate payroll record unit numbers, it must furnish the following: (1) The name of each payroll record unit for the coverage group; and (2...
15 CFR 280.323 - Transfer or assignment of the trademark registration or recorded insignia.
Code of Federal Regulations, 2011 CFR
2011-01-01
... Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF... trademark application or registration which forms the basis of a certificate of recordal, the Director, USPTO, shall designate the certificate of recordal as inactive. The certificate of recordal shall be...
15 CFR 280.323 - Transfer or assignment of the trademark registration or recorded insignia.
Code of Federal Regulations, 2010 CFR
2010-01-01
... Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF... trademark application or registration which forms the basis of a certificate of recordal, the Director, USPTO, shall designate the certificate of recordal as inactive. The certificate of recordal shall be...
15 CFR 908.8 - Maintenance of records.
Code of Federal Regulations, 2011 CFR
2011-01-01
... RECORDS AND SUBMITTING REPORTS ON WEATHER MODIFICATION ACTIVITIES § 908.8 Maintenance of records. (a) Any person engaging in a weather modification activity in the United States shall maintain a record of such... assigned to the project, the designation of each unit of weather modification apparatus, and at least the...
Chemicals identified in human biological media: a data base. Third annual report, October 1981
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cone, M.V.; Baldauf, M.F.; Martin, F.M.
Data from almost 1600 of the 3800 body-burden documents collected to date have been entered in the data base as of October 1981. The emphasis on including recent literature and significant research documents has resulted in a chronological mix of articles from 1974 to the present. When body-burden articles are identified, data are extracted and entered in the data base by chemical and tissue/body fluid. Each data entry comprises a single record (or line entry) and is assigned a record number. If a particular document deals with more than one chemical and/or tissue, there will be multiple records for thatmore » document. For example, a study of 5 chemicals in each of 3 tissues has 15 different records (or 15 line entries) in the data base with 15 record numbers. Record numbers are assigned consecutively throughout the entire data base and appear in the upper left corner of the first column for each record.« less
Evaluation of a flipped classroom approach to learning introductory epidemiology.
Shiau, Stephanie; Kahn, Linda G; Platt, Jonathan; Li, Chihua; Guzman, Jason T; Kornhauser, Zachary G; Keyes, Katherine M; Martins, Silvia S
2018-04-02
Although the flipped classroom model has been widely adopted in medical education, reports on its use in graduate-level public health programs are limited. This study describes the design, implementation, and evaluation of a flipped classroom redesign of an introductory epidemiology course and compares it to a traditional model. One hundred fifty Masters-level students enrolled in an introductory epidemiology course with a traditional format (in-person lecture and discussion section, at-home assignment; 2015, N = 72) and a flipped classroom format (at-home lecture, in-person discussion section and assignment; 2016, N = 78). Using mixed methods, we compared student characteristics, examination scores, and end-of-course evaluations of the 2016 flipped classroom format and the 2015 traditional format. Data on the flipped classroom format, including pre- and post-course surveys, open-ended questions, self-reports of section leader teaching practices, and classroom observations, were evaluated. There were no statistically significant differences in examination scores or students' assessment of the course between 2015 (traditional) and 2016 (flipped). In 2016, 57.1% (36) of respondents to the end-of-course evaluation found watching video lectures at home to have a positive impact on their time management. Open-ended survey responses indicated a number of strengths of the flipped classroom approach, including the freedom to watch pre-recorded lectures at any time and the ability of section leaders to clarify targeted concepts. Suggestions for improvement focused on ways to increase regular interaction with lecturers. There was no significant difference in students' performance on quantitative assessments comparing the traditional format to the flipped classroom format. The flipped format did allow for greater flexibility and applied learning opportunities at home and during discussion sections.
Bruera, Eduardo; Valero, Vicente; Driver, Larry; Shen, Loren; Willey, Jie; Zhang, Tao; Palmer, J Lynn
2006-05-01
To evaluate the effectiveness of patient-controlled methylphenidate as compared with placebo in cancer patients with fatigue, as measured by the Functional Assessment for Chronic Illness Therapy-Fatigue (FACIT-F). Patients with a fatigue score of at least 4 on a scale of 0 to 10 (0 = no fatigue, 10 = worst possible fatigue) and hemoglobin level of at least 10 g/dL were included. Patients were randomly assigned to receive 5 mg methylphenidate or placebo every 2 hours as needed (maximum of four capsules a day), for 7 days. Patients completed a daily diary including study drug record and fatigue intensity. A research nurse telephoned patients daily to assess toxicity and fatigue level. All patients were offered open-label methylphenidate for 4 weeks. FACIT-F and the Edmonton Symptom Assessment System (ESAS) were assessed at baseline, and days 8, 15, and 36. The FACIT-F fatigue subscore on day 8 was considered the primary end point. Of 112 patients randomly assigned, 52 patients in the methylphenidate and 53 in the placebo group were assessable for analysis. Fatigue intensity improved significantly on day 8 in both the methylphenidate and placebo groups. However, there was no significant difference in fatigue improvement by FACIT-F (P = .31) or ESAS (P = .14) between groups. In open-label phase, fatigue intensity maintained low as compared with baseline. No significant toxicities were observed. Both methylphenidate and placebo resulted in significant symptom improvement. Methylphenidate was not significantly superior to placebo after 1 week of treatment. Longer study duration is justified. The role of daily telephone calls from a research nurse should be explored as a palliative care intervention.
15 CFR 990.61 - Administrative record.
Code of Federal Regulations, 2010 CFR
2010-01-01
... NATURAL RESOURCE DAMAGE ASSESSMENTS Restoration Implementation Phase § 990.61 Administrative record. (a... regarding the Final Restoration Plan. (b) Opening an administrative record for restoration implementation. Trustees may open an administrative record for implementation of restoration, as provided in § 990.45 of...
Code of Federal Regulations, 2014 CFR
2014-07-01
... AND VIDEO RECORDINGS § 142.1 Purpose. This part provides policy, prescribes procedures, and assigned responsibilities regarding the use of copyrighted sound and video recordings within the Department of Defense. ...
ERIC Educational Resources Information Center
Zehavi, Nurit
This study explored student mathematical activity in open problem-solving situations, derived from the work of Polya on problem solving and Skemp on intelligent learning and teaching. Assignment projects with problems for ninth-grade students were developed, whether they elicit the desired cognitive and cogno-affective goals was investigated, and…
ERIC Educational Resources Information Center
Cochran, H. Keith
This paper contains two scenario-type assignments for students in a university tests and measurements class as well as a collection of materials developed by actual students in response to these assignments. An opening explanation argues that education students, often nearing the end of their program when they take the tests and measurement…
The purpose of this SOP is to outline HHID and IRN assignment during the Arizona NHEXAS project and the Border study. Keywords: field; records; HHID and IRN assignment.
The U.S.-Mexico Border Program is sponsored by the Environmental Health Workgroup of the Border 2012 Program....
Animal Guts as Ideal Reactors: An Open-Ended Project for a Course in Kinetics and Reactor Design.
ERIC Educational Resources Information Center
Carlson, Eric D.; Gast, Alice P.
1998-01-01
Presents an open-ended project tailored for a senior kinetics and reactor design course in which basic reactor design equations are used to model the digestive systems of several animals. Describes the assignment as well as the results. (DDR)
37 CFR 3.54 - Effect of recording.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Effect of recording. 3.54... COMMERCE GENERAL ASSIGNMENT, RECORDING AND RIGHTS OF ASSIGNEE Date and Effect of Recording § 3.54 Effect of... validity of the document or the effect that document has on the title to an application, a patent, or a...
Acute effects of different dynamic exercises on hamstring strain risk factors.
Chen, Che Hsiu; Xin, Ye; Lee, Kuang Wu; Lin, Ming Ju; Lin, Jiu Jenq
2018-01-01
The purpose of the study was to examine the acute effects of different dynamic exercise interventions on hamstring muscle performance. Thirty-six young men with poor hamstring flexibility were randomly assigned to three intervention groups: jogging combined with dynamic open kinetic chain stretching (DS), jogging combined with dynamic closed kinetic chain stretching (lunge with eccentric hamstring windmills, LEC), and jogging only (CON) groups. Hamstring flexibility, muscle stiffness (area under the curve, AUC), joint position sense (JPS), maximal eccentric strength (ECC), and angle of peak torque (APT) were recorded before and immediately after the exercise interventions. The results showed that the hamstring flexibility increased in DS (p < 0.001); muscle stiffness decreased in DS and was lower than jogging (p < 0.001). Moreover, ECC increased in LEC and was higher than jogging and DS (p < 0.001). APT was different among 3 groups (p < 0.001). Decreased accuracy of JPS was found in DS and jogging (p < 0.001). In conclusion, the dynamic closed kinetic chain stretching (LEC) as compared to open kinetic chain stretching (DS) or jogging group, may be an effective technique to enhance muscle performance during the pre-competition warm-up routine.
Acute effects of different dynamic exercises on hamstring strain risk factors
Xin, Ye; Lee, Kuang Wu; Lin, Ming Ju
2018-01-01
The purpose of the study was to examine the acute effects of different dynamic exercise interventions on hamstring muscle performance. Thirty-six young men with poor hamstring flexibility were randomly assigned to three intervention groups: jogging combined with dynamic open kinetic chain stretching (DS), jogging combined with dynamic closed kinetic chain stretching (lunge with eccentric hamstring windmills, LEC), and jogging only (CON) groups. Hamstring flexibility, muscle stiffness (area under the curve, AUC), joint position sense (JPS), maximal eccentric strength (ECC), and angle of peak torque (APT) were recorded before and immediately after the exercise interventions. The results showed that the hamstring flexibility increased in DS (p < 0.001); muscle stiffness decreased in DS and was lower than jogging (p < 0.001). Moreover, ECC increased in LEC and was higher than jogging and DS (p < 0.001). APT was different among 3 groups (p < 0.001). Decreased accuracy of JPS was found in DS and jogging (p < 0.001). In conclusion, the dynamic closed kinetic chain stretching (LEC) as compared to open kinetic chain stretching (DS) or jogging group, may be an effective technique to enhance muscle performance during the pre-competition warm-up routine. PMID:29390001
Open Access to Geophysical Data
NASA Astrophysics Data System (ADS)
Sergeyeva, Nataliya A.; Zabarinskaya, Ludmila P.
2017-04-01
Russian World Data Centers for Solar-Terrestrial Physics & Solid Earth Physics hosted by the Geophysical Center of the Russian Academy of Sciences are the Regular Members of the ICSU-World Data System. Guided by the principles of the WDS Constitution and WDS Data Sharing Principles, the WDCs provide full and open access to data, long-term data stewardship, compliance with agreed-upon data standards and conventions, and mechanisms to facilitate and improve access to data. Historical and current geophysical data on different media, in the form of digital data sets, analog records, collections of maps, descriptions are stored and collected in the Centers. The WDCs regularly fill up repositories and database with new data, support them up to date. Now the WDCs focus on four new projects, aimed at increase of data available in network by retrospective data collection and digital preservation of data; creation of a modern system of registration and publication of data with digital object identifier (DOI) assignment, and promotion of data citation culture; creation of databases instead of file system for more convenient access to data; participation in the WDS Metadata Catalogue and Data Portal by creating of metadata for information resources of WDCs.
75 FR 1683 - Financial Management Service; Proposed Collection of Information: Assignment Form
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-12
... DEPARTMENT OF THE TREASURY Fiscal Service Financial Management Service; Proposed Collection of Information: Assignment Form AGENCY: Financial Management Service, Fiscal Service, Treasury. ACTION: Notice... Management Service, Records and Information Management Branch, Room 135, 3700 East West Highway, Hyattsville...
Code of Federal Regulations, 2011 CFR
2011-01-01
.... The participant's Social Security number will remain the identifier for the submission of data and... individual or other identifying particular assigned to the individual; (l) Statistical record means a record in a system of records maintained for statistical research or reporting purposes only and not used in...
The late Middle Pleistocene hominin fossil record of eastern Asia: synthesis and review.
Bae, Christopher J
2010-01-01
Traditionally, Middle Pleistocene hominin fossils that cannot be allocated to Homo erectus sensu lato or modern H. sapiens have been assigned to different specific taxa. For example, in eastern Asia, these hominin fossils have been classified as archaic, early, or premodern H. sapiens. An increasing number of Middle Pleistocene hominin fossils are currently being assigned to H. heidelbergensis. This is particularly the case for the African and European Middle Pleistocene hominin fossil record. There have been suggestions that perhaps the eastern Asian late Middle Pleistocene hominins can also be allocated to the H. heidelbergensis hypodigm. In this article, I review the current state of the late Middle Pleistocene hominin fossil record from eastern Asia and examine the various arguments for assigning these hominins to the different specific taxa. The two primary conclusions drawn from this review are as follows: 1) little evidence currently exists in the eastern Asian Middle Pleistocene hominin fossil record to support their assignment to H. heidelbergensis; and 2) rather than add to the growing list of hominin fossil taxa by using taxonomic names like H. daliensis for northeast Asian fossils and H. mabaensis for Southeast Asian fossils, it is better to err on the side of caution and continue to use the term archaic H. sapiens to represent all of these hominin fossils. What should be evident from this review is the need for an increase in the quality and quantity of the eastern Asian hominin fossil data set. Fortunately, with the increasing number of large-scale multidisciplinary paleoanthropological field and laboratory research projects in eastern Asia, the record is quickly becoming better understood. Copyright © 2010 Wiley-Liss, Inc.
Novel, Effective, Whole: Toward a NEW Framework for Evaluations of Creative Products
ERIC Educational Resources Information Center
Henriksen, Danah; Mishra, Punya; Mehta, Rohit
2015-01-01
Creativity is increasingly viewed as an important 21st century skill that needs to be taught in schools. This emphasis on creativity is often reflected by having students engage in open-ended, project based activities and assignments. A key challenge faced by educators is how such assignments are to be evaluated. An in-depth review of existing…
ERIC Educational Resources Information Center
Riegelman, Elizabeth D.; And Others
The effects of an oven timer as an antecedent stimulus on study behavior and concurrent completion and accuracy of reading and writing assignments were investigated for an 8-year-old first grade repeater who lacked motivation. Following baseline observations during which the teacher recorded study behavior and collected assignments with no…
As'adi, Kamran; Emami, Seyed Abolhassan; Salehi, Seyed Hamid; Shoar, Saeed
2016-08-01
Tissue expansion has evolved reconstruction surgery by providing a great source of additional tissue for large skin defects. Nevertheless, wide application of tissue expander reconstruction is challenging due to high complication rates and uncertainty about final outcomes. Recently, endoscopy has shown promise in reconstructive surgeries using tissue expander placement. This study aimed to compare outcomes between open and endoscopic-assisted neck tissue expander placement in reconstruction of post-burn facial scar deformities. Through a randomized clinical trial, 63 patients with facial burn scars were assigned to an open group or endoscopic group for placement of 81 tissue expanders. The complication rate, operative time, length of hospital stay, and time to full expansion were compared between the two groups. Thirty-one patients were assigned to the open group and 32 patients to the endoscopic group. The average operative time was significantly reduced in the endoscopic group compared with the open group (42.2 ± 3.6, 56.5 ± 4.5 min, p < 0.05). The complication rate was significantly lower in the endoscopic group than the open group (6 vs. 16, p < 0.05). Hospital stay was also significantly diminished from 26.3 ± 7.7 h in open group to 7.4 ± 4.5 h in endoscopic group (p < 0.0001). There was a significant reduction in time to full expansion in the endoscopic group as compared with the open group (93.5 ± 10.2 vs. 112.1 ± 14.2 days, p = 0.002). Endoscopic neck tissue expander placement significantly reduced operative time, the postoperative complication rate, length of hospital stay, and time to achieve full expansion and allowed early initiation of expansion and remote placement of the port in relation to the expander pocket. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
NASA Technical Reports Server (NTRS)
Callac, Christopher; Lunsford, Michelle
2005-01-01
The NASA Records Database, comprising a Web-based application program and a database, is used to administer an archive of paper records at Stennis Space Center. The system begins with an electronic form, into which a user enters information about records that the user is sending to the archive. The form is smart : it provides instructions for entering information correctly and prompts the user to enter all required information. Once complete, the form is digitally signed and submitted to the database. The system determines which storage locations are not in use, assigns the user s boxes of records to some of them, and enters these assignments in the database. Thereafter, the software tracks the boxes and can be used to locate them. By use of search capabilities of the software, specific records can be sought by box storage locations, accession numbers, record dates, submitting organizations, or details of the records themselves. Boxes can be marked with such statuses as checked out, lost, transferred, and destroyed. The system can generate reports showing boxes awaiting destruction or transfer. When boxes are transferred to the National Archives and Records Administration (NARA), the system can automatically fill out NARA records-transfer forms. Currently, several other NASA Centers are considering deploying the NASA Records Database to help automate their records archives.
19 CFR 146.3 - Customs supervision.
Code of Federal Regulations, 2010 CFR
2010-04-01
... (CONTINUED) FOREIGN TRADE ZONES General Provisions § 146.3 Customs supervision. (a) Assignment of Customs officers. Customs officers will be assigned or detailed to a zone as necessary to maintain appropriate Customs supervision of merchandise and records pertaining thereto in the zone, and to protect the revenue...
19 CFR 146.3 - Customs supervision.
Code of Federal Regulations, 2014 CFR
2014-04-01
... (CONTINUED) FOREIGN TRADE ZONES General Provisions § 146.3 Customs supervision. (a) Assignment of Customs officers. Customs officers will be assigned or detailed to a zone as necessary to maintain appropriate Customs supervision of merchandise and records pertaining thereto in the zone, and to protect the revenue...
19 CFR 146.3 - Customs supervision.
Code of Federal Regulations, 2011 CFR
2011-04-01
... (CONTINUED) FOREIGN TRADE ZONES General Provisions § 146.3 Customs supervision. (a) Assignment of Customs officers. Customs officers will be assigned or detailed to a zone as necessary to maintain appropriate Customs supervision of merchandise and records pertaining thereto in the zone, and to protect the revenue...
19 CFR 146.3 - Customs supervision.
Code of Federal Regulations, 2013 CFR
2013-04-01
... (CONTINUED) FOREIGN TRADE ZONES General Provisions § 146.3 Customs supervision. (a) Assignment of Customs officers. Customs officers will be assigned or detailed to a zone as necessary to maintain appropriate Customs supervision of merchandise and records pertaining thereto in the zone, and to protect the revenue...
19 CFR 146.3 - Customs supervision.
Code of Federal Regulations, 2012 CFR
2012-04-01
... (CONTINUED) FOREIGN TRADE ZONES General Provisions § 146.3 Customs supervision. (a) Assignment of Customs officers. Customs officers will be assigned or detailed to a zone as necessary to maintain appropriate Customs supervision of merchandise and records pertaining thereto in the zone, and to protect the revenue...
Code of Federal Regulations, 2011 CFR
2011-01-01
... competitive levels within the pay band, including (as appropriate) any applicable locality payment authorized... and forth daily to their usual employment. Modal rating is the summary rating level assigned most frequently among the actual ratings of record that are: (1) Assigned under the summary level pattern that...
32 CFR 505.3 - Privacy Act systems of records.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 32 National Defense 3 2011-07-01 2009-07-01 true Privacy Act systems of records. 505.3 Section 505... AND PUBLIC RELATIONS ARMY PRIVACY ACT PROGRAM § 505.3 Privacy Act systems of records. (a) Systems of... assigned to an individual. (2) Privacy Act systems of records must be— (i) Authorized by Federal statute or...
32 CFR 505.3 - Privacy Act systems of records.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 32 National Defense 3 2014-07-01 2014-07-01 false Privacy Act systems of records. 505.3 Section... AUTHORITIES AND PUBLIC RELATIONS ARMY PRIVACY ACT PROGRAM § 505.3 Privacy Act systems of records. (a) Systems... assigned to an individual. (2) Privacy Act systems of records must be— (i) Authorized by Federal statute or...
32 CFR 505.3 - Privacy Act systems of records.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 32 National Defense 3 2013-07-01 2013-07-01 false Privacy Act systems of records. 505.3 Section... AUTHORITIES AND PUBLIC RELATIONS ARMY PRIVACY ACT PROGRAM § 505.3 Privacy Act systems of records. (a) Systems... assigned to an individual. (2) Privacy Act systems of records must be— (i) Authorized by Federal statute or...
32 CFR 505.3 - Privacy Act systems of records.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 32 National Defense 3 2012-07-01 2009-07-01 true Privacy Act systems of records. 505.3 Section 505... AND PUBLIC RELATIONS ARMY PRIVACY ACT PROGRAM § 505.3 Privacy Act systems of records. (a) Systems of... assigned to an individual. (2) Privacy Act systems of records must be— (i) Authorized by Federal statute or...
43 CFR 3106.4-1 - Transfers of record title and of operating rights (subleases).
Code of Federal Regulations, 2014 CFR
2014-10-01
... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Transfers of record title and of operating... LEASING Transfers by Assignment, Sublease or Otherwise § 3106.4-1 Transfers of record title and of operating rights (subleases). Each transfer of record title or of an operating right (sublease) shall be...
43 CFR 3106.4-1 - Transfers of record title and of operating rights (subleases).
Code of Federal Regulations, 2011 CFR
2011-10-01
... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Transfers of record title and of operating... LEASING Transfers by Assignment, Sublease or Otherwise § 3106.4-1 Transfers of record title and of operating rights (subleases). Each transfer of record title or of an operating right (sublease) shall be...
43 CFR 3106.4-1 - Transfers of record title and of operating rights (subleases).
Code of Federal Regulations, 2013 CFR
2013-10-01
... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Transfers of record title and of operating... LEASING Transfers by Assignment, Sublease or Otherwise § 3106.4-1 Transfers of record title and of operating rights (subleases). Each transfer of record title or of an operating right (sublease) shall be...
43 CFR 3106.4-1 - Transfers of record title and of operating rights (subleases).
Code of Federal Regulations, 2012 CFR
2012-10-01
... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Transfers of record title and of operating... LEASING Transfers by Assignment, Sublease or Otherwise § 3106.4-1 Transfers of record title and of operating rights (subleases). Each transfer of record title or of an operating right (sublease) shall be...
Laws of reflection and Snell's law revisited by video modeling
NASA Astrophysics Data System (ADS)
Rodrigues, M.; Simeão Carvalho, P.
2014-07-01
Video modelling is being used, nowadays, as a tool for teaching and learning several topics in Physics. Most of these topics are related to kinematics. In this work we show how video modelling can be used for demonstrations and experimental teaching in optics, namely the laws of reflection and the well-known Snell's Law of light. Videos were recorded with a photo camera at 30 frames/s, and analysed with the open source software Tracker. Data collected from several frames was treated with the Data Tool module, and graphs were built to obtain relations between incident, reflected and refraction angles, as well as to determine the refractive index of Perspex. These videos can be freely distributed in the web and explored with students within the classroom, or as a homework assignment to improve student's understanding on specific contents. They present a large didactic potential for teaching basic optics in high school with an interactive methodology.
ERIC Educational Resources Information Center
Evans, Barbara; Honour, Leslie
1997-01-01
Reports on a study that required student teachers training in business education to produce open learning materials on intercultural communication. Analysis of stages and responses to this assignment revealed a distinction between "deep" and "surface" learning. Includes charts delineating the characteristics of these two types…
An Investigation of Graduate Student Knowledge and Usage of Open-Access Journals
ERIC Educational Resources Information Center
Beard, Regina M.
2016-01-01
Graduate students lament the need to achieve the proficiency necessary to competently search multiple databases for their research assignments, regularly eschewing these sources in favor of Google Scholar or some other search engine. The author conducted an anonymous survey investigating graduate student knowledge or awareness of the open-access…
77 FR 56627 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-13
... proposed action will be effective on October 15, 2012 unless comments are received which result in a... readiness, manpower, labor cost assignment, education, and training, for personnel across the DoD medical... essential manpower, personnel, labor cost assignment, education and training, and personnel readiness...
The Impact on Institutional Research of Open Meeting and Open Records Laws in Higher Education.
ERIC Educational Resources Information Center
Letzring, Timothy D.
1997-01-01
Institutional researchers should know state and federal laws and attorneys general opinions applicable to higher education concerning open meetings and open records, and be prepared for information requests by media and concerned citizens. Case law is examined, and practical steps researchers can take are outlined, including knowing who will…
21 CFR 606.165 - Distribution and receipt; procedures and records.
Code of Federal Regulations, 2010 CFR
2010-04-01
... SERVICES (CONTINUED) BIOLOGICS CURRENT GOOD MANUFACTURING PRACTICE FOR BLOOD AND BLOOD COMPONENTS Records..., or for crossmatched blood and blood components, the name of the recipient. (c) Receipt records shall contain the name and address of the collecting facility, date received, donor or lot number assigned by...
76 FR 28757 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-18
... Elementary and Secondary Schools; 20 U.S.C. 921-932, Overseas Defense Dependents Education; DoD Directive.... Categories of records in the system: Records consist of first name, last name, Social Security Number (SSN... school or organization, identification numbers assigned to each school and office facility, grade level...
Medicare Part D Roulette: Potential Implications of Random Assignment and Plan Restrictions
Patel, Rajul A.; Walberg, Mark P.; Woelfel, Joseph A.; Amaral, Michelle M.; Varu, Paresh
2013-01-01
Background Dual-eligible (Medicare/Medicaid) beneficiaries are randomly assigned to a benchmark plan, which provides prescription drug coverage under the Part D benefit without consideration of their prescription drug profile. To date, the potential for beneficiary assignment to a plan with poor formulary coverage has been minimally studied and the resultant financial impact to beneficiaries unknown. Objective We sought to determine cost variability and drug use restrictions under each available 2010 California benchmark plan. Methods Dual-eligible beneficiaries were provided Part D plan assistance during the 2010 annual election period. The Medicare Web site was used to determine benchmark plan costs and prescription utilization restrictions for each of the six California benchmark plans available for random assignment in 2010. A standardized survey was used to record all de-identified beneficiary demographic and plan specific data. For each low-income subsidy-recipient (n = 113), cost, rank, number of non-formulary medications, and prescription utilization restrictions were recorded for each available 2010 California benchmark plan. Formulary matching rates (percent of beneficiary's medications on plan formulary) were calculated for each benchmark plan. Results Auto-assigned beneficiaries had only a 34% chance of being assigned to the lowest cost plan; the remainder faced potentially significant avoidable out-of-pocket costs. Wide variations between benchmark plans were observed for plan cost, formulary coverage, formulary matching rates, and prescription utilization restrictions. Conclusions Beneficiaries had a 66% chance of being assigned to a sub-optimal plan; thereby, they faced significant avoidable out-of-pocket costs. Alternative methods of beneficiary assignment could decrease beneficiary and Medicare costs while also reducing medication non-compliance. PMID:24753963
Open access publishing, article downloads, and citations: randomised controlled trial
Lewenstein, Bruce V; Simon, Daniel H; Booth, James G; Connolly, Mathew J L
2008-01-01
Objective To measure the effect of free access to the scientific literature on article downloads and citations. Design Randomised controlled trial. Setting 11 journals published by the American Physiological Society. Participants 1619 research articles and reviews. Main outcome measures Article readership (measured as downloads of full text, PDFs, and abstracts) and number of unique visitors (internet protocol addresses). Citations to articles were gathered from the Institute for Scientific Information after one year. Interventions Random assignment on online publication of articles published in 11 scientific journals to open access (treatment) or subscription access (control). Results Articles assigned to open access were associated with 89% more full text downloads (95% confidence interval 76% to 103%), 42% more PDF downloads (32% to 52%), and 23% more unique visitors (16% to 30%), but 24% fewer abstract downloads (−29% to −19%) than subscription access articles in the first six months after publication. Open access articles were no more likely to be cited than subscription access articles in the first year after publication. Fifty nine per cent of open access articles (146 of 247) were cited nine to 12 months after publication compared with 63% (859 of 1372) of subscription access articles. Logistic and negative binomial regression analysis of article citation counts confirmed no citation advantage for open access articles. Conclusions Open access publishing may reach more readers than subscription access publishing. No evidence was found of a citation advantage for open access articles in the first year after publication. The citation advantage from open access reported widely in the literature may be an artefact of other causes. PMID:18669565
9 CFR 2.75 - Records: Dealers and exhibitors.
Code of Federal Regulations, 2014 CFR
2014-01-01
... of, including by euthanasia; (vi) The official USDA tag number or tattoo assigned to a dog or cat..., death, euthanasia, or donation. (2) Each dealer and exhibitor shall use Record of Aquisition and Dogs...
9 CFR 2.75 - Records: Dealers and exhibitors.
Code of Federal Regulations, 2011 CFR
2011-01-01
... of, including by euthanasia; (vi) The official USDA tag number or tattoo assigned to a dog or cat..., death, euthanasia, or donation. (2) Each dealer and exhibitor shall use Record of Aquisition and Dogs...
9 CFR 2.75 - Records: Dealers and exhibitors.
Code of Federal Regulations, 2013 CFR
2013-01-01
... of, including by euthanasia; (vi) The official USDA tag number or tattoo assigned to a dog or cat..., death, euthanasia, or donation. (2) Each dealer and exhibitor shall use Record of Aquisition and Dogs...
9 CFR 2.75 - Records: Dealers and exhibitors.
Code of Federal Regulations, 2012 CFR
2012-01-01
... of, including by euthanasia; (vi) The official USDA tag number or tattoo assigned to a dog or cat..., death, euthanasia, or donation. (2) Each dealer and exhibitor shall use Record of Aquisition and Dogs...
NASA Technical Reports Server (NTRS)
Panait, Claudia M.
2004-01-01
The NASA Glenn Library is a science and engineering research library providing the most current books, journals, CD-ROM's and documents to support the study of aeronautics, space propulsion and power, communications technology, materials and structures and microgravity science. The GRC technical library also supports the research and development efforts of all scientists and engineers on site via full text electronic files, literature searching, technical reports, etc. As an intern in the NASA Glenn Library, I attempt to support these objectives through efficiently and effectively fulfilling the assignment that was given to me. The assignment that was relegated to me was to catalog National Advisory Committee for Aeronautics, NASA Technical Documents into NASA Galaxie. This process consists of holdings being added to existing Galaxie records, upgrades and editing done to the bibliographic records when needed, adding URL's into Galaxie when they were missing from the record. NASA ASAP and Digidoc was used to locate URL's of PDF's that were not in Galaxie. A spreadsheet of documents with no URL's were maintained. Also, a subject channel of web, fill-text, paid and free, journal and other subject specific pages were developed and expanded fiom current content of intranet pages. To expand upon the second half of my assignment, I was given the project of taking inventory of the library s book collection. I kept record of the books that were not accounted for on a master list I was given to work fiom and submitted them for correction and addition. I also made sure the books were placed in the appropriate order and made corrections to any discrepancies that existed between the master list and what was on the shelf. Upon completion of this assignment, I will have verified that 21,113 books were in the correct location, order and have the correct corresponding serial number and barcode. In conclusion, as of this date I have input around 750 documents into NASA Galaxie, inputting about half of the NASA Technical Documents into the system. The rest of my tenure in this program will consist of finishing the other half of the reports. In regard to the second assignment, I still have about three-quarters of the collection to record and correct.
Johnston, Stephen Rd; Kilburn, Lucy S; Ellis, Paul; Dodwell, David; Cameron, David; Hayward, Larry; Im, Young-Hyuck; Braybrooke, Jeremy P; Brunt, A Murray; Cheung, Kwok-Leung; Jyothirmayi, Rema; Robinson, Anne; Wardley, Andrew M; Wheatley, Duncan; Howell, Anthony; Coombes, Gill; Sergenson, Nicole; Sin, Hui-Jung; Folkerd, Elizabeth; Dowsett, Mitch; Bliss, Judith M
2013-09-01
The optimum endocrine treatment for postmenopausal women with advanced hormone-receptor-positive breast cancer that has progressed on non-steroidal aromatase inhibitors (NSAIs) is unclear. The aim of the SoFEA trial was to assess a maximum double endocrine targeting approach with the steroidal anti-oestrogen fulvestrant in combination with continued oestrogen deprivation. In a composite, multicentre, phase 3 randomised controlled trial done in the UK and South Korea, postmenopausal women with hormone-receptor-positive breast cancer (oestrogen receptor [ER] positive, progesterone receptor [PR] positive, or both) were eligible if they had relapsed or progressed with locally advanced or metastatic disease on an NSAI (given as adjuvant for at least 12 months or as first-line treatment for at least 6 months). Additionally, patients had to have adequate organ function and a WHO performance status of 0-2. Participants were randomly assigned (1:1:1) to receive fulvestrant (500 mg intramuscular injection on day 1, followed by 250 mg doses on days 15 and 29, and then every 28 days) plus daily oral anastrozole (1 mg); fulvestrant plus anastrozole-matched placebo; or daily oral exemestane (25 mg). Randomisation was done with computer-generated permuted blocks, and stratification was by centre and previous use of an NSAI as adjuvant treatment or for locally advanced or metastatic disease. Participants and investigators were aware of assignment to fulvestrant or exemestane, but not of assignment to anastrozole or placebo. The primary endpoint was progression-free survival (PFS). Analyses were by intention to treat. This trial is registered with ClinicalTrials.gov, numbers NCT00253422 (UK) and NCT00944918 (South Korea). Between March 26, 2004, and Aug 6, 2010, 723 patients underwent randomisation: 243 were assigned to receive fulvestrant plus anastrozole, 231 to fulvestrant plus placebo, and 249 to exemestane. Median PFS was 4·4 months (95% CI 3·4-5·4) in patients assigned to fulvestrant plus anastrozole, 4·8 months (3·6-5·5) in those assigned to fulvestrant plus placebo, and 3·4 months (3·0-4·6) in those assigned to exemestane. No difference was recorded between the patients assigned to fulvestrant plus anastrozole and fulvestrant plus placebo (hazard ratio 1·00, 95% CI 0·83-1·21; log-rank p=0·98), or between those assigned to fulvestrant plus placebo and exemestane (0·95, 0·79-1·14; log-rank p=0·56). 87 serious adverse events were reported: 36 in patients assigned to fulvestrant plus anastrozole, 22 in those assigned to fulvestrant plus placebo, and 29 in those assigned to exemestane. Grade 3-4 adverse events were rare; the most frequent were arthralgia (three in the group assigned to fulvestrant plus anastrozole; seven in that assigned to fulvestrant plus placebo; eight in that assigned to exemestane), lethargy (three; 11; 11), and nausea or vomiting (five; two; eight). After loss of response to NSAIs in postmenopausal women with hormone-receptor-positive advanced breast cancer, maximum double endocrine treatment with 250 mg fulvestrant combined with oestrogen deprivation is no better than either fulvestrant alone or exemestane. Copyright © 2013 Johnston et al. Open Access article distributed under the terms of CC BY-NC-SA. Published by Elsevier Ltd. All rights reserved.
[Multiplexing mapping of human cDNAs]. Final report, September 1, 1991--February 28, 1994
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
Using PCR with automated product analysis, 329 human brain cDNA sequences have been assigned to individual human chromosomes. Primers were designed from single-pass cDNA sequences expressed sequence tags (ESTs). Primers were used in PCR reactions with DNA from somatic cell hybrid mapping panels as templates, often with multiplexing. Many ESTs mapped match sequence database records. To evaluate of these matches, the position of the primers relative to the matching region (In), the BLAST scores and the Poisson probability values of the EST/sequence record match were determined. In cases where the gene product was stringently identified by the sequence match hadmore » already been mapped, the gene locus determined by EST was consistent with the previous position which strongly supports the validity of assigning unknown genes to human chromosomes based on the EST sequence matches. In the present cases mapping the ESTs to a chromosome can also be considered to have mapped the known gene product: rolipram-sensitive cAMP phosphodiesterase, chromosome 1; protein phosphatase 2A{beta}, chromosome 4; alpha-catenin, chromosome 5; the ELE1 oncogene, chromosome 10q11.2 or q2.1-q23; MXII protein, chromosome l0q24-qter; ribosomal protein L18a homologue, chromosome 14; ribosomal protein L3, chromosome 17; and moesin, Xp11-cen. There were also ESTs mapped that were closely related to non-human sequence records. These matches therefore can be considered to identify human counterparts of known gene products, or members of known gene families. Examples of these include membrane proteins, translation-associated proteins, structural proteins, and enzymes. These data then demonstrate that single pass sequence information is sufficient to design PCR primers useful for assigning cDNA sequences to human chromosomes. When the EST sequence matches previous sequence database records, the chromosome assignments of the EST can be used to make preliminary assignments of the human gene to a chromosome.« less
ERIC Educational Resources Information Center
Bartholomew, Scott R.; Nadelson, Louis S.; Goodridge, Wade H.; Reeve, Edward M.
2018-01-01
We investigated the use of adaptive comparative judgment to evaluate the middle school student learning, engagement, and experience with the design process in an open-ended problem assigned in a technology and engineering education course. Our results indicate that the adaptive comparative judgment tool effectively facilitated the grading of the…
ERIC Educational Resources Information Center
Montague, Margariete A.
This study investigated the feasibility of concurrently and randomly sampling examinees and items in order to estimate group achievement. Seven 32-item tests reflecting a 640-item universe of simple open sentences were used such that item selection (random, systematic) and assignment (random, systematic) of items (four, eight, sixteen) to forms…
Historical open forest ecosystems in the Missouri Ozarks: reconstruction and restoration targets
Brice B. Hanberry; D. Todd Jones-Farrand; John M. Kabrick
2014-01-01
Current forests no longer resemble historical open forest ecosystems in the eastern United States. In the absence of representative forest ecosystems under a continuous surface fire regime at a large scale, reconstruction of historical landscapes can provide a reference for restoration efforts. For initial expert-assigned vegetation phases ranging from prairie to...
Using student writing assignments to assess critical thinking skills: a holistic approach.
Niedringhaus, L K
2001-04-01
This work offers an example of one school's holistic approach to the evaluation of critical thinking by using student writing assignments. Faculty developed tools to assess achievement of critical thinking competencies, such as analysis, synthesis, insight, reflection, open mindedness, and depth, breadth, and appropriateness of clinical interventions. Faculty created a model for the development of program-specific critical thinking competencies, selected appropriate writing assignments that demonstrate critical thinking, and implemented a holistic assessment plan for data collection and analysis. Holistic assessment involves the identification of shared values and practices, and the use of concepts and language important to nursing.
Foraminiferal Stable Isotope Record at Millville, NJ: Implications for the onset of the PETM
NASA Astrophysics Data System (ADS)
Wright, J. D.; Miller, K. G.
2016-12-01
Traditional paleoceanographic tools (magneto-biostratigraphy, orbital cycles) are insufficient to assign rates to the initial release of carbon during the rapid onset of the PETM (<10 kyr). The ODP Leg 174AX Millville, NJ PETM section (70 m paleodepth) is >10 times more expanded relative to the thickest open ocean sites (e.g., Site 690). The onset interval at Millville is defined by a bulk carbonate δ13C of 3.5‰ across 25 cm interval. Two groups used the geochemical changes to constrain the timing for the initial pulse of carbon. Wright and Schaller (2013) focused on the differential responses in δ13C and %CaCO3 arguing that the release was fast (<1 year). Conversely, Zeebe et al. (2016) assumed the initial covariance in δ18O and δ13C represented equilibrium conditions, modeling a 4 kyr duration for the release. We generated planktonic and benthic foraminiferal stable isotope records across the onset of the PETM CIE at Millville. Most of the δ13C change recorded by foraminifera occurred over the 25 cm onset interval. However, foraminiferal δ18O values continue to decrease for another 1.5 m above the initial δ13C decrease contradicting Zeebe et al.'s assumption of equilibrium conditions. The foraminiferal stable isotope pattern is similar to the modeled response following a large, instantaneous release of light carbon to the atmosphere, that produces a rapid (decadal) scale warming in the surface air masses followed by continued warming but at a slower rate. Differential responses in δ13C, δ18O, and %CaCO3 at the onset of the PETM are consistent with an instantaneous initial release of carbon with centennial-scale warming that continued well after the initial carbon pulse similar to that predicted by climate models. Fitting the Millville isotope records to these models suggests that peak warmth followed the initial release by 100 to 200 years. The mid-shelf location of Millville a made it responsive to atmospheric changes unlike open ocean sites where thermal inertia dampens the larger atmosphere changes.
Agent-based Large-Scale Emergency Evacuation Using Real-Time Open Government Data
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lu, Wei; Liu, Cheng; Bhaduri, Budhendra L
The open government initiatives have provided tremendous data resources for the transportation system and emergency services in urban areas. This paper proposes a traffic simulation framework using high temporal resolution demographic data and real time open government data for evacuation planning and operation. A comparison study using real-world data in Seattle, Washington is conducted to evaluate the framework accuracy and evacuation efficiency. The successful simulations of selected area prove the concept to take advantage open government data, open source data, and high resolution demographic data in emergency management domain. There are two aspects of parameters considered in this study: usermore » equilibrium (UE) conditions of traffic assignment model (simple Non-UE vs. iterative UE) and data temporal resolution (Daytime vs. Nighttime). Evacuation arrival rate, average travel time, and computation time are adopted as Measure of Effectiveness (MOE) for evacuation performance analysis. The temporal resolution of demographic data has significant impacts on urban transportation dynamics during evacuation scenarios. Better evacuation performance estimation can be approached by integrating both Non-UE and UE scenarios. The new framework shows flexibility in implementing different evacuation strategies and accuracy in evacuation performance. The use of this framework can be explored to day-to-day traffic assignment to support daily traffic operations.« less
ERIC Educational Resources Information Center
Barak, Moshe; Assal, Muhammad
2018-01-01
This study presents the case of development and evaluation of a STEM-oriented 30-h robotics course for junior high school students (n = 32). Class activities were designed according to the P3 Task Taxonomy, which included: (1) practice-basic closed-ended tasks and exercises; (2) problem solving--small-scale open-ended assignments in which the…
17 CFR 16.01 - Trading volume, open contracts, prices, and critical dates.
Code of Federal Regulations, 2012 CFR
2012-04-01
... TRADING COMMISSION REPORTS BY REPORTING MARKETS § 16.01 Trading volume, open contracts, prices, and critical dates. (a) Trading volume and open contracts. Each reporting market shall record for each business... total volume of trading. (b) Prices. Each reporting market shall record the following information...
46 CFR 15.1107 - Maintenance of merchant mariners' records by owner or operator.
Code of Federal Regulations, 2010 CFR
2010-10-01
... responsible for the safety of the vessel and for the prevention of marine pollution: (a) Medical fitness (such...., record of training completed, and of relevant on-the-job experience acquired). (c) Competency in assigned...
Adoptive Parents' Attitudes Toward Open Birth Records.
ERIC Educational Resources Information Center
Geissinger, Shirley
1984-01-01
Investigated adoptive parents' (N=42) attitudes toward the open birth record issues using a mail survey. Analysis indicated that parental fear was the most important variable. Most supported a measure allowing adult adoptees access to birth records, provided such access was agreeable to birth and adoptive parents. (JAC)
Sensing Attribute Weights: A Novel Basic Belief Assignment Method
Jiang, Wen; Zhuang, Miaoyan; Xie, Chunhe; Wu, Jun
2017-01-01
Dempster–Shafer evidence theory is widely used in many soft sensors data fusion systems on account of its good performance for handling the uncertainty information of soft sensors. However, how to determine basic belief assignment (BBA) is still an open issue. The existing methods to determine BBA do not consider the reliability of each attribute; at the same time, they cannot effectively determine BBA in the open world. In this paper, based on attribute weights, a novel method to determine BBA is proposed not only in the closed world, but also in the open world. The Gaussian model of each attribute is built using the training samples firstly. Second, the similarity between the test sample and the attribute model is measured based on the Gaussian membership functions. Then, the attribute weights are generated using the overlap degree among the classes. Finally, BBA is determined according to the sensed attribute weights. Several examples with small datasets show the validity of the proposed method. PMID:28358325
Sensing Attribute Weights: A Novel Basic Belief Assignment Method.
Jiang, Wen; Zhuang, Miaoyan; Xie, Chunhe; Wu, Jun
2017-03-30
Dempster-Shafer evidence theory is widely used in many soft sensors data fusion systems on account of its good performance for handling the uncertainty information of soft sensors. However, how to determine basic belief assignment (BBA) is still an open issue. The existing methods to determine BBA do not consider the reliability of each attribute; at the same time, they cannot effectively determine BBA in the open world. In this paper, based on attribute weights, a novel method to determine BBA is proposed not only in the closed world, but also in the open world. The Gaussian model of each attribute is built using the training samples firstly. Second, the similarity between the test sample and the attribute model is measured based on the Gaussian membership functions. Then, the attribute weights are generated using the overlap degree among the classes. Finally, BBA is determined according to the sensed attribute weights. Several examples with small datasets show the validity of the proposed method.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-29
...; Federal Perkins Loan Program/NDSL Assignment Form SUMMARY: The Federal Perkins Loan Program allows for... exhausted all of its efforts in recovering an outstanding loan. The Perkins Assignment Form serves as the... to this notice will be considered public records. Title of Collection: Federal Perkins Loan Program...
Captain's Log...The Speech Communication Oral Journal.
ERIC Educational Resources Information Center
Strong, William F.
1983-01-01
The logic and the benefits of requiring college students in basic speech communication classes to tape-record oral journals are set forth along with a detailed description of the assignment. Instructions to the students explain the mechanics of the assignment as follows: (1) obtain and properly label a quality cassette tape; (2) make seven…
Preparing Computing Students for Culturally Diverse E-Mediated IT Projects
ERIC Educational Resources Information Center
Conrad, Marc; French, Tim; Maple, Carsten; Zhang, Sijing
2006-01-01
In this paper we present an account of an undergraduate team-based assignment designed to facilitate, exhibit and record team-working skills in an e-mediated environment. By linking the student feedback received to Hofstede's classic model of cultural dimensions we aim to show the assignment's suitability in revealing the student's multi-cultural…
Beach Books: 2016-2017. What Do Colleges and Universities Want Students to Read outside Class?
ERIC Educational Resources Information Center
Randall, David
2017-01-01
"Beach Books 2016-17," which covers 348 colleges and universities, continues the National Association of Scholars' long-running record of providing the most comprehensive information about colleges and universities that assign common readings to incoming freshmen. Although there are several databases of common reading assignments, Beach…
Bringing the Universe to the World: Lessons Learned from a Massive Open Online Class on Astronomy
NASA Astrophysics Data System (ADS)
Impey, C.; Wenger, M.; Formanek, M.; Buxner, S.
2016-12-01
This paper presents the results of a massive open online class (MOOC) on astronomy called Astronomy: Exploring Time and Space. The class was hosted by the web platform Coursera and ran for six weeks from February to May 2015. Coverage was designed to emphasise topics in astronomy where there has been rapid research progress, including large telescopes, exploration of the Solar System, the discovery of exoplanets, exotic end states of stars, and the frontiers of cosmology. The core content was nearly eighteen hours of video lectures, assessed by thirteen video lecture quizzes, three peer review writing assignments, and two online activities. Information on demographics and on the goals and motivations of the learners was gathered using standard Coursera entry and exit surveys and an external Science Literacy survey. A total of 25 379 people registered for the course, and most of them did not complete any assignments. About two-thirds of the 14 900 learners who opened the course lived outside the United States, distributed across 151 different countries. Out of 4275 participants who completed one or more assignments, 1607 passed the course, and a majority did so with a grade of 80% or higher. Those who completed the course were generally very satisfied with their experience and felt it met their learning goals. The people with the highest chance of completing the course tended to be in the range 40 to 60 years old, had a college education, and were either retired or working in professional fields. The strongest predictors of passing the course were to have completed the first written assignment or the first online activity.
MetAMOS: a modular and open source metagenomic assembly and analysis pipeline
2013-01-01
We describe MetAMOS, an open source and modular metagenomic assembly and analysis pipeline. MetAMOS represents an important step towards fully automated metagenomic analysis, starting with next-generation sequencing reads and producing genomic scaffolds, open-reading frames and taxonomic or functional annotations. MetAMOS can aid in reducing assembly errors, commonly encountered when assembling metagenomic samples, and improves taxonomic assignment accuracy while also reducing computational cost. MetAMOS can be downloaded from: https://github.com/treangen/MetAMOS. PMID:23320958
Design Support System for Open Distance Learning Student Teamwork
NASA Astrophysics Data System (ADS)
Putranto, A.; Pradipto, Y. D.
2017-01-01
Open distance learning students in doing team assignment, they seldom face to some problems such as student fell unfair in numbers of workload contribution, instructors also do not know which students do more work than others. So there are some questions ie: how to connect between instructor, team members, and working documents. Methods will be used are first, analyzing current condition and last by designing systems to connect between instructor, team members, and document. The expected result is support systems for open distance learning student teamwork.
32 CFR 701.122 - Medical records.
Code of Federal Regulations, 2011 CFR
2011-07-01
... THE NAVY DOCUMENTS AFFECTING THE PUBLIC DON Privacy Program § 701.122 Medical records. (a) Health Information Portability and Accountability Act (HIPAA). (1) DOD Directive 6025.18 establishes policies and assigns responsibilities for implementation of the standards for privacy of individually identifiable...
32 CFR 701.122 - Medical records.
Code of Federal Regulations, 2010 CFR
2010-07-01
... THE NAVY DOCUMENTS AFFECTING THE PUBLIC DON Privacy Program § 701.122 Medical records. (a) Health Information Portability and Accountability Act (HIPAA). (1) DOD Directive 6025.18 establishes policies and assigns responsibilities for implementation of the standards for privacy of individually identifiable...
ERIC Educational Resources Information Center
Murdock, Margaret; Holman, R. W.; Slade, Tyler; Clark, Shelley L. D.; Rodnick, Kenneth J.
2014-01-01
A unique homework assignment has been designed as a review exercise to be implemented near the end of the one-year undergraduate organic chemistry sequence. Within the framework of the exercise, students derive potential mechanisms for glucose ring opening in the aqueous mutarotation process. In this endeavor, 21 general review principles are…
1981-10-01
unique alphanumeric designation assigned by the performing orga- nization or provided by the sponsoring organization in accordance with American...for cataloging. (b). Identifiers and Open-Ended Terms. Use identifiers for project names, code names, equipment designators , etc. Use open- ended...spool. Note. These components ae designed to function together or with the BASS alone, if internal control of job processing is not a requirement at a
ERIC Educational Resources Information Center
Olivier, Benjamin Hugh
2016-01-01
This study investigated the impact of face-to-face contact sessions and online discussion forums on the academic performance of students at an Open Distance Learning (ODL) university (N = 1,015). t-Tests for independent samples indicated that students who attended a written assignment preparation contact session performed significantly better in…
Undecidability and Irreducibility Conditions for Open-Ended Evolution and Emergence.
Hernández-Orozco, Santiago; Hernández-Quiroz, Francisco; Zenil, Hector
2018-01-01
Is undecidability a requirement for open-ended evolution (OEE)? Using methods derived from algorithmic complexity theory, we propose robust computational definitions of open-ended evolution and the adaptability of computable dynamical systems. Within this framework, we show that decidability imposes absolute limits on the stable growth of complexity in computable dynamical systems. Conversely, systems that exhibit (strong) open-ended evolution must be undecidable, establishing undecidability as a requirement for such systems. Complexity is assessed in terms of three measures: sophistication, coarse sophistication, and busy beaver logical depth. These three complexity measures assign low complexity values to random (incompressible) objects. As time grows, the stated complexity measures allow for the existence of complex states during the evolution of a computable dynamical system. We show, however, that finding these states involves undecidable computations. We conjecture that for similar complexity measures that assign low complexity values, decidability imposes comparable limits on the stable growth of complexity, and that such behavior is necessary for nontrivial evolutionary systems. We show that the undecidability of adapted states imposes novel and unpredictable behavior on the individuals or populations being modeled. Such behavior is irreducible. Finally, we offer an example of a system, first proposed by Chaitin, that exhibits strong OEE.
Montero, J; Gómez Polo, C; Rosel, E; Barrios, R; Albaladejo, A; López-Valverde, A
2016-01-01
Symmetric, aligned and luminous smiles are usually classified as 'beautiful' and aesthetic. However, smile perception is not strictly governed by standardised rules. Personal traits may influence the perception of non-ideal smiles. We aimed to determine the influence of personality traits in self-rated oral health and satisfaction and in the aesthetic preference for different strategically flawed smiles shown in photographs. Smiles with dark teeth, with uneven teeth, with lip asymmetry and dental asymmetry were ordered from 1 to 4 as a function of the degree of beauty by 548 participants, of which 50·7% were females with a mean age of 41·5 ± 17·6 years (range: 16-89 years). Self-assessment and oral satisfaction were recorded on a Likert scale. Personality was measured by means of the Big Five Inventory (extraversion, agreeableness, conscientiousness, neuroticism and openness), and the Life Orientation Test was used to measure optimism and pessimism. Of the four photographs with imperfect smiles, dental asymmetry was the most highly assessed in 63% of the sample, and the worst was lip asymmetry, in 43·7% of the sample. Some personality traits (above all conscientiousness and openness) were significantly correlated with the position assigned to the photographs with dental and lip asymmetry or with misaligned teeth. The extraversion, agreeableness and openness traits were correlated with the self-perceptions of oral health and aesthetics of the participants. Dental asymmetry seems to be better tolerated than lip asymmetry. Personality traits are weakly but significantly correlated with the aesthetic preference and oral health values, conscientiousness and openness being the most relevant domains in this sense. © 2015 John Wiley & Sons Ltd.
ERIC Educational Resources Information Center
Community Health Service (DHEW/PHS), Arlington, VA. Div. of Health Resources.
The manual provides major topics, objectives, activities and, procedures, references and materials, and assignments for the training program. The topics covered are hospital organization and community role, organization and management of a medical records department, international classification of diseases and operations, medical terminology,…
Open Access Metadata, Catalogers, and Vendors: The Future of Cataloging Records
ERIC Educational Resources Information Center
Flynn, Emily Alinder
2013-01-01
The open access (OA) movement is working to transform scholarly communication around the world, but this philosophy can also apply to metadata and cataloging records. While some notable, large academic libraries, such as Harvard University, the University of Michigan, and the University of Cambridge, released their cataloging records under OA…
25 CFR 226.30 - Lessees subject to Superintendent's orders; books and records open to inspection.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 25 Indians 1 2014-04-01 2014-04-01 false Lessees subject to Superintendent's orders; books and... Lessees § 226.30 Lessees subject to Superintendent's orders; books and records open to inspection. Lessee.... Lessee's books and records shall be available to the Superintendent for inspection. ...
A clinic compatible, open source electrophysiology system.
Hermiz, John; Rogers, Nick; Kaestner, Erik; Ganji, Mehran; Cleary, Dan; Snider, Joseph; Barba, David; Dayeh, Shadi; Halgren, Eric; Gilja, Vikash
2016-08-01
Open source electrophysiology (ephys) recording systems have several advantages over commercial systems such as customization and affordability enabling more researchers to conduct ephys experiments. Notable open source ephys systems include Open-Ephys, NeuroRighter and more recently Willow, all of which have high channel count (64+), scalability, and advanced software to develop on top of. However, little work has been done to build an open source ephys system that is clinic compatible, particularly in the operating room where acute human electrocorticography (ECoG) research is performed. We developed an affordable (<; $10,000) and open system for research purposes that features power isolation for patient safety, compact and water resistant enclosures and 256 recording channels sampled up to 20ksam/sec, 16-bit. The system was validated by recording ECoG with a high density, thin film device for an acute, awake craniotomy study at UC San Diego, Thornton Hospital Operating Room.
Using Audioblogs to Assist English-Language Learning: An Investigation into Student Perception
ERIC Educational Resources Information Center
Hsu, Hui-Yin; Wang, Shiang-Kwei; Comac, Linda
2008-01-01
This pilot study investigates how the use of audioblogs can help to meet an instructor's need to improve instruction in English as a second language (ESL). In this study, the instructor uses audioblogs to manage oral assignments, to interact with learners, and to evaluate performance outcomes. Learners record oral assignments through cellular…
Students' Understanding and Perceptions of Assigned Team Roles in a Classroom Laboratory Environment
ERIC Educational Resources Information Center
Ott, Laura E.; Kephart, Kerrie; Stolle-McAllister, Kathleen; LaCourse, William R.
2018-01-01
Using a cooperative learning framework in a quantitative reasoning laboratory course, students were assigned to static teams of four in which they adopted roles that rotated regularly. The roles included: team leader, protocol manager, data recorder, and researcher. Using a mixed-methods approach, we investigated students' perceptions of the team…
EarthEd Online: Open Source Online Software to Support Large Courses
NASA Astrophysics Data System (ADS)
Prothero, W. A.
2003-12-01
The purpose of the EarthEd Online software project is to support a modern instructional pedagogy in a large, college level, earth science course. It is an ongoing development project that has evolved in a large general education oceanography course over the last decade. Primary goals for the oceanography course are to support learners in acquiring a knowledge of science process, an appreciation for the relevance of science to society, and basic content knowledge. In order to support these goals, EarthEd incorporates: a) integrated access to various kinds of real earth data (and links to web-based data browsers), b) online discussions, live chat, with integrated graphics editing, linking, and upload, c) online writing, reviewing, and grading, d) online homework assignments, e) on demand grade calculation, and f) instructor grade entry and progress reports. The software was created using Macromedia Director. It is distributed to students on a CDROM and updates are downloaded and installed automatically. Data browsers for plate tectonics relevant data ("Our Dynamic Planet"), a virtual exploration of the East Pacific Rise, the World Ocean Atlas-98, and a fishing simulation game are integrated with the EarthEd software. The system is modular which allows new capabilities, such as new data browsers, to be added. Student reactions to the software are positive overall. They are especially appreciative of the on demand grade computation capability. The online writing, commenting and grading is particularly effective in managing the large number of papers that get submitted. The TA's grade the papers, but the instructor can provide feedback to them as they grade the papers, and a record is maintained of all comments and rubric item grades. Commenting is made easy by simply "dragging" a selection of pre-defined comments into the student's text. Scoring is supported by an integrated scoring rubric. All assignments, rubrics, etc. are configured in text files that are downloaded from the course web server. Students rate the writing assignments as the most effective learning activity in the course. This project is in an evaluation and dissemination phase. An open source model is planned for distribution. For documentation and information about the EarthEd team, see: http://oceanography.geol.ucsb.edu/Collab/software.html
Empowering open systems through cross-platform interoperability
NASA Astrophysics Data System (ADS)
Lyke, James C.
2014-06-01
Most of the motivations for open systems lie in the expectation of interoperability, sometimes referred to as "plug-and-play". Nothing in the notion of "open-ness", however, guarantees this outcome, which makes the increased interest in open architecture more perplexing. In this paper, we explore certain themes of open architecture. We introduce the concept of "windows of interoperability", which can be used to align disparate portions of architecture. Such "windows of interoperability", which concentrate on a reduced set of protocol and interface features, might achieve many of the broader purposes assigned as benefits in open architecture. Since it is possible to engineer proprietary systems that interoperate effectively, this nuanced definition of interoperability may in fact be a more important concept to understand and nurture for effective systems engineering and maintenance.
Kaafarani, H M A; Hur, K; Campasano, M; Reda, D J; Itani, K M F
2010-06-01
Generic instruments used for the valuation of health states (e.g., EuroQol) often lack sensitivity to notable differences that are relevant to particular diseases or interventions. We developed a valuation methodology specifically for complications following ventral incisional herniorrhaphy (VIH). Between 2004 and 2006, 146 patients were prospectively randomized to undergo laparoscopic (n = 73) or open (n = 73) VIH. The primary outcome of the trial was complications at 8 weeks. A three-step methodology was used to assign severity weights to complications. First, each complication was graded using the Clavien classification. Second, five reviewers were asked to independently and directly rate their perception of the severity of each class using a non-categorized visual analog scale. Zero represented an uncomplicated postoperative course, while 100 represented postoperative death. Third, the median, lowest, and highest values assigned to each class of complications were used to derive weighted complication scores for open and laparoscopic VIH. Open VIH had more complications than laparoscopic VIH (47.9 vs. 31.5%, respectively; P = 0.026). However, complications of laparoscopic VIH were more severe than those of open VIH. Non-parametric analysis revealed a statistically higher weighted complication score for open VIH (interquartile range: 0-20 for open vs. 0-10 for laparoscopic; P = 0.049). In the sensitivity analysis, similar results were obtained using the median, highest, and lowest weights. We describe a new methodology for the valuation of complications following VIH that allows a direct outcome comparison of procedures with different complication profiles. Further testing of the validity, reliability, and generalizability of this method is warranted.
Automatically tracking neurons in a moving and deforming brain
Nguyen, Jeffrey P.; Linder, Ashley N.; Plummer, George S.; Shaevitz, Joshua W.
2017-01-01
Advances in optical neuroimaging techniques now allow neural activity to be recorded with cellular resolution in awake and behaving animals. Brain motion in these recordings pose a unique challenge. The location of individual neurons must be tracked in 3D over time to accurately extract single neuron activity traces. Recordings from small invertebrates like C. elegans are especially challenging because they undergo very large brain motion and deformation during animal movement. Here we present an automated computer vision pipeline to reliably track populations of neurons with single neuron resolution in the brain of a freely moving C. elegans undergoing large motion and deformation. 3D volumetric fluorescent images of the animal’s brain are straightened, aligned and registered, and the locations of neurons in the images are found via segmentation. Each neuron is then assigned an identity using a new time-independent machine-learning approach we call Neuron Registration Vector Encoding. In this approach, non-rigid point-set registration is used to match each segmented neuron in each volume with a set of reference volumes taken from throughout the recording. The way each neuron matches with the references defines a feature vector which is clustered to assign an identity to each neuron in each volume. Finally, thin-plate spline interpolation is used to correct errors in segmentation and check consistency of assigned identities. The Neuron Registration Vector Encoding approach proposed here is uniquely well suited for tracking neurons in brains undergoing large deformations. When applied to whole-brain calcium imaging recordings in freely moving C. elegans, this analysis pipeline located 156 neurons for the duration of an 8 minute recording and consistently found more neurons more quickly than manual or semi-automated approaches. PMID:28545068
Automatically tracking neurons in a moving and deforming brain.
Nguyen, Jeffrey P; Linder, Ashley N; Plummer, George S; Shaevitz, Joshua W; Leifer, Andrew M
2017-05-01
Advances in optical neuroimaging techniques now allow neural activity to be recorded with cellular resolution in awake and behaving animals. Brain motion in these recordings pose a unique challenge. The location of individual neurons must be tracked in 3D over time to accurately extract single neuron activity traces. Recordings from small invertebrates like C. elegans are especially challenging because they undergo very large brain motion and deformation during animal movement. Here we present an automated computer vision pipeline to reliably track populations of neurons with single neuron resolution in the brain of a freely moving C. elegans undergoing large motion and deformation. 3D volumetric fluorescent images of the animal's brain are straightened, aligned and registered, and the locations of neurons in the images are found via segmentation. Each neuron is then assigned an identity using a new time-independent machine-learning approach we call Neuron Registration Vector Encoding. In this approach, non-rigid point-set registration is used to match each segmented neuron in each volume with a set of reference volumes taken from throughout the recording. The way each neuron matches with the references defines a feature vector which is clustered to assign an identity to each neuron in each volume. Finally, thin-plate spline interpolation is used to correct errors in segmentation and check consistency of assigned identities. The Neuron Registration Vector Encoding approach proposed here is uniquely well suited for tracking neurons in brains undergoing large deformations. When applied to whole-brain calcium imaging recordings in freely moving C. elegans, this analysis pipeline located 156 neurons for the duration of an 8 minute recording and consistently found more neurons more quickly than manual or semi-automated approaches.
High-resolution photoabsorption spectrum of jet-cooled propyne
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jacovella, U.; Holland, D. M. P.; Boyé-Péronne, S.
2014-09-21
The absolute photoabsorption cross section of propyne was recorded between 62 000 and 88 000 cm{sup −1} by using the vacuum-ultraviolet, Fourier-transform spectrometer at the Synchrotron Soleil. This cross section spans the region including the lowest Rydberg bands and extends above the Franck-Condon envelope for ionization to the ground electronic state of the propyne cation, X{sup ~+}. Room-temperature spectra were recorded in a flowing cell at 0.9 cm{sup −1} resolution, and jet-cooled spectra were recorded at 1.8 cm{sup −1} resolution and a rotational temperature of ∼100 K. The reduced widths of the rotational band envelopes in the latter spectra reveal new structuremore » and simplify a number of assignments. Although nf Rydberg series have not been assigned previously in the photoabsorption spectrum of propyne, arguments are presented for their potential importance, and the assignment of one nf series is proposed. As expected from previous photoelectron spectra, Rydberg series are also observed above the adiabatic ionization threshold that converge to the v{sub 3}{sup +} = 1 and 2 levels of the C≡C stretching vibration.« less
Patel, Mehul D; Rose, Kathryn M; Owens, Cindy R; Bang, Heejung; Kaufman, Jay S
2012-03-01
Occupational data are a common source of workplace exposure and socioeconomic information in epidemiologic research. We compared the performance of two occupation coding methods, an automated software and a manual coder, using occupation and industry titles from U.S. historical records. We collected parental occupational data from 1920-40s birth certificates, Census records, and city directories on 3,135 deceased individuals in the Atherosclerosis Risk in Communities (ARIC) study. Unique occupation-industry narratives were assigned codes by a manual coder and the Standardized Occupation and Industry Coding software program. We calculated agreement between coding methods of classification into major Census occupational groups. Automated coding software assigned codes to 71% of occupations and 76% of industries. Of this subset coded by software, 73% of occupation codes and 69% of industry codes matched between automated and manual coding. For major occupational groups, agreement improved to 89% (kappa = 0.86). Automated occupational coding is a cost-efficient alternative to manual coding. However, some manual coding is required to code incomplete information. We found substantial variability between coders in the assignment of occupations although not as large for major groups.
Executive Council lists and general practitioner files
Farmer, R. D. T.; Knox, E. G.; Cross, K. W.; Crombie, D. L.
1974-01-01
An investigation of the accuracy of general practitioner and Executive Council files was approached by a comparison of the two. High error rates were found, including both file errors and record errors. On analysis it emerged that file error rates could not be satisfactorily expressed except in a time-dimensioned way, and we were unable to do this within the context of our study. Record error rates and field error rates were expressible as proportions of the number of records on both the lists; 79·2% of all records exhibited non-congruencies and particular information fields had error rates ranging from 0·8% (assignation of sex) to 68·6% (assignation of civil state). Many of the errors, both field errors and record errors, were attributable to delayed updating of mutable information. It is concluded that the simple transfer of Executive Council lists to a computer filing system would not solve all the inaccuracies and would not in itself permit Executive Council registers to be used for any health care applications requiring high accuracy. For this it would be necessary to design and implement a purpose designed health care record system which would include, rather than depend upon, the general practitioner remuneration system. PMID:4816588
ERIC Educational Resources Information Center
Scrivener, Susan; Coghlan, Erin
2011-01-01
Only one-third of all students who enter community colleges with the intent to earn a degree or certificate actually meet this goal within six years. MDRC launched the Opening Doors Demonstration in 2003--the first large-scale random assignment study in a community college setting--to tackle this problem. Partnering with six community colleges,…
ERIC Educational Resources Information Center
Moore, Kristin A.; Caal, Selma; Lawner, Elizabeth K.; Rojas, Angela; Walker, Karen
2014-01-01
Child Trends conducted a random assignment evaluation of the Abriendo Puertas/Opening Doors program, one of the largest programs in the United States working with low-income Latino parents of children ages zero to five. Since it began in 2007, the program has served over 30,000 parents/families in 34 states. The evaluation study examined the…
ERIC Educational Resources Information Center
Hendricks, Christina; Reinsberg, Stefan A.; Rieger, Georg
2017-01-01
Assigning open textbooks in college and university courses can help students save money on increasingly expensive commercial textbooks, and recent research shows that this savings can often be achieved with little to no sacrifice in textbook quality or student learning outcomes. We add to this body of research by examining the use of an open…
76 FR 55057 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-06
... Records. System location: U.S. Army Human Resources Command, Education Incentives Branch, 1600 Spearhead... Social Security Number (SSN); Military Occupational Specialty (MOS). Student Loan: Qualifying student loan name, amount of loan, date of loan transaction, student education loan number assigned by the...
An RFID Based Smart Feeder for Hummingbirds.
Ibarra, Vicente; Araya-Salas, Marcelo; Tang, Yu-ping; Park, Charlie; Hyde, Anthony; Wright, Timothy F; Tang, Wei
2015-12-16
We present an interdisciplinary effort to record feeding behaviors and control the diet of a hummingbird species (Phaethornis longirostris, the long-billed hermit or LBH) by developing a Radio Frequency Identification (RFID) based smart feeder. The system contains an RFID reader, a microcontroller, and a servo-controlled hummingbird feeder opener; the system is presented as a tool for studying the cognitive ability of the LBH species. When equipped with glass capsule RFID tags (which are mounted on the hummingbird), the smart feeder can provide specific diets for predetermined sets of hummingbirds at the discretion of biologists. This is done by reading the unique RFID tag on the hummingbirds and comparing the ID number with the pre-programmed ID numbers stored in the smart feeder. The smart feeder records the time and ID of each hummingbird visit. The system data is stored in a readily available SD card and is powered by two 9 V batteries. The detection range of the system is approximately 9-11 cm. Using this system, biologists can assign the wild hummingbirds to different experimental groups and monitor their diets to determine if they develop a preference to any of the available nectars. During field testing, the smart feeder system has demonstrated consistent detection (when compared to detections observed by video-recordings) of RFID tags on hummingbirds and provides pre-designed nectars varying water and sugar concentrations to target individuals. The smart feeder can be applied to other biological and environmental studies in the future.
An RFID Based Smart Feeder for Hummingbirds
Ibarra, Vicente; Araya-Salas, Marcelo; Tang, Yu-ping; Park, Charlie; Hyde, Anthony; Wright, Timothy F.; Tang, Wei
2015-01-01
We present an interdisciplinary effort to record feeding behaviors and control the diet of a hummingbird species (Phaethornis longirostris, the long-billed hermit or LBH) by developing a Radio Frequency Identification (RFID) based smart feeder. The system contains an RFID reader, a microcontroller, and a servo-controlled hummingbird feeder opener; the system is presented as a tool for studying the cognitive ability of the LBH species. When equipped with glass capsule RFID tags (which are mounted on the hummingbird), the smart feeder can provide specific diets for predetermined sets of hummingbirds at the discretion of biologists. This is done by reading the unique RFID tag on the hummingbirds and comparing the ID number with the pre-programmed ID numbers stored in the smart feeder. The smart feeder records the time and ID of each hummingbird visit. The system data is stored in a readily available SD card and is powered by two 9 V batteries. The detection range of the system is approximately 9–11 cm. Using this system, biologists can assign the wild hummingbirds to different experimental groups and monitor their diets to determine if they develop a preference to any of the available nectars. During field testing, the smart feeder system has demonstrated consistent detection (when compared to detections observed by video-recordings) of RFID tags on hummingbirds and provides pre-designed nectars varying water and sugar concentrations to target individuals. The smart feeder can be applied to other biological and environmental studies in the future. PMID:26694402
Code of Federal Regulations, 2011 CFR
2011-10-01
... Assigning Working Freeboards to Hopper Dredges § 44.310 Definitions. Hopper dredge means a self-propelled dredge with an open hold or hopper in the hull of the dredge that receives dredged material. Working...
Code of Federal Regulations, 2010 CFR
2010-10-01
... Assigning Working Freeboards to Hopper Dredges § 44.310 Definitions. Hopper dredge means a self-propelled dredge with an open hold or hopper in the hull of the dredge that receives dredged material. Working...
Wanderer, Jonathan P; Charnin, Jonathan; Driscoll, William D; Bailin, Michael T; Baker, Keith
2013-08-01
Our goal in this study was to develop decision support systems for resident operating room (OR) assignments using anesthesia information management system (AIMS) records and Accreditation Council for Graduate Medical Education (ACGME) case logs and evaluate the implementations. We developed 2 Web-based systems: an ACGME case-log visualization tool, and Residents Helping in Navigating OR Scheduling (Rhinos), an interactive system that solicits OR assignment requests from residents and creates resident profiles. Resident profiles are snapshots of the cases and procedures each resident has done and were derived from AIMS records and ACGME case logs. A Rhinos pilot was performed for 6 weeks on 2 clinical services. One hundred sixty-five requests were entered and used in OR assignment decisions by a single attending anesthesiologist. Each request consisted of a rank ordered list of up to 3 ORs. Residents had access to detailed information about these cases including surgeon and patient name, age, procedure type, and admission status. Success rates at matching resident requests were determined by comparing requests with AIMS records. Of the 165 requests, 87 first-choice matches (52.7%), 27 second-choice matches (16.4%), and 8 third-choice matches (4.8%) were made. Forty-three requests were unmatched (26.1%). Thirty-nine first-choice requests overlapped (23.6%). Full implementation followed on 8 clinical services for 8 weeks. Seven hundred fifty-four requests were reviewed by 15 attending anesthesiologists, with 339 first-choice matches (45.0%), 122 second-choice matches (16.2%), 55 third-choice matches (7.3%), and 238 unmatched (31.5%). There were 279 overlapping first-choice requests (37.0%). The overall combined match success rate was 69.4%. Separately, we developed an ACGME case-log visualization tool that allows individual resident experiences to be compared against case minimums as well as resident peer groups. We conclude that it is feasible to use ACGME case-log data in decision support systems for informing resident OR assignments. Additional analysis will be necessary to assess the educational impact of these systems.
ERIC Educational Resources Information Center
Vergara-Martinez, Marta; Perea, Manuel; Marin, Alejandro; Carreiras, Manuel
2011-01-01
Recent research suggests that there is a processing distinction between consonants and vowels in visual-word recognition. Here we conjointly examine the time course of consonants and vowels in processes of letter identity and letter position assignment. Event related potentials (ERPs) were recorded while participants read words and pseudowords in…
43 CFR 3106.7-2 - If I transfer my lease, what is my continuing obligation?
Code of Federal Regulations, 2013 CFR
2013-10-01
... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false If I transfer my lease, what is my... LEASING Transfers by Assignment, Sublease or Otherwise § 3106.7-2 If I transfer my lease, what is my... BLM approves an assignment of your record title interest or transfer of your operating rights. (b...
43 CFR 3106.7-2 - If I transfer my lease, what is my continuing obligation?
Code of Federal Regulations, 2012 CFR
2012-10-01
... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false If I transfer my lease, what is my... LEASING Transfers by Assignment, Sublease or Otherwise § 3106.7-2 If I transfer my lease, what is my... BLM approves an assignment of your record title interest or transfer of your operating rights. (b...
43 CFR 3106.7-2 - If I transfer my lease, what is my continuing obligation?
Code of Federal Regulations, 2011 CFR
2011-10-01
... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false If I transfer my lease, what is my... LEASING Transfers by Assignment, Sublease or Otherwise § 3106.7-2 If I transfer my lease, what is my... BLM approves an assignment of your record title interest or transfer of your operating rights. (b...
VizieR Online Data Catalog: Proper motions of PM2000 open clusters (Krone-Martins+, 2010)
NASA Astrophysics Data System (ADS)
Krone-Martins, A.; Soubiran, C.; Ducourant, C.; Teixeira, R.; Le Campion, J. F.
2010-04-01
We present lists of proper-motions and kinematic membership probabilities in the region of 49 open clusters or possible open clusters. The stellar proper motions were taken from the Bordeaux PM2000 catalogue. The segregation between cluster and field stars and the assignment of membership probabilities was accomplished by applying a fully automated method based on parametrisations for the probability distribution functions and genetic algorithm optimisation heuristics associated with a derivative-based hill climbing algorithm for the likelihood optimization. (3 data files).
75 FR 58368 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-24
... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID DOD-2010-OS-0125] Privacy Act of 1974... Register Liaison Officer, Department of Defense. ZDO-001 System name: Accountability Records/Recall Rosters... commissaries, including Department of Defense (DoD) Federal employees, military service personnel not assigned...
75 FR 56533 - Privacy Act System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-16
... add one new system of records, FCC/OMD-23, ``Cadapult Space Management System (CSMS).'' The FCC's Space Management Center (SMC) in the Office of Managing Director (OMD) will use the CSMS information... and contractors following the FCC/National Treasury Union (NTEU) space assignment policy. In the event...
14 CFR 49.15 - Fees for recording.
Code of Federal Regulations, 2014 CFR
2014-01-01
... therein $5.00 (2) Conveyance, made for security purposes, of a specifically identified aircraft engine or propeller, or any assignment or amendment thereof, or supplement thereto, recorded under Subpart D— For each engine or propeller 5.00 (3) Conveyance, made for security purposes, of aircraft engines, propellers...
14 CFR 49.15 - Fees for recording.
Code of Federal Regulations, 2012 CFR
2012-01-01
... therein $5.00 (2) Conveyance, made for security purposes, of a specifically identified aircraft engine or propeller, or any assignment or amendment thereof, or supplement thereto, recorded under Subpart D— For each engine or propeller 5.00 (3) Conveyance, made for security purposes, of aircraft engines, propellers...
14 CFR 49.15 - Fees for recording.
Code of Federal Regulations, 2013 CFR
2013-01-01
... therein $5.00 (2) Conveyance, made for security purposes, of a specifically identified aircraft engine or propeller, or any assignment or amendment thereof, or supplement thereto, recorded under Subpart D— For each engine or propeller 5.00 (3) Conveyance, made for security purposes, of aircraft engines, propellers...
14 CFR 49.15 - Fees for recording.
Code of Federal Regulations, 2010 CFR
2010-01-01
... therein $5.00 (2) Conveyance, made for security purposes, of a specifically identified aircraft engine or propeller, or any assignment or amendment thereof, or supplement thereto, recorded under Subpart D— For each engine or propeller 5.00 (3) Conveyance, made for security purposes, of aircraft engines, propellers...
14 CFR 49.15 - Fees for recording.
Code of Federal Regulations, 2011 CFR
2011-01-01
... therein $5.00 (2) Conveyance, made for security purposes, of a specifically identified aircraft engine or propeller, or any assignment or amendment thereof, or supplement thereto, recorded under Subpart D— For each engine or propeller 5.00 (3) Conveyance, made for security purposes, of aircraft engines, propellers...
Code of Federal Regulations, 2011 CFR
2011-10-01
..., symbol, or other identifying particular assigned to the individual; (e) System record means a group of... U.S. Commission on Civil Rights; (b) Individual means a citizen of the United States or an alien...) Record means any item, collection, or grouping of information about an individual that is maintained by...
Code of Federal Regulations, 2014 CFR
2014-10-01
..., symbol, or other identifying particular assigned to the individual; (e) System record means a group of... U.S. Commission on Civil Rights; (b) Individual means a citizen of the United States or an alien...) Record means any item, collection, or grouping of information about an individual that is maintained by...
Code of Federal Regulations, 2010 CFR
2010-10-01
..., symbol, or other identifying particular assigned to the individual; (e) System record means a group of... U.S. Commission on Civil Rights; (b) Individual means a citizen of the United States or an alien...) Record means any item, collection, or grouping of information about an individual that is maintained by...
Code of Federal Regulations, 2012 CFR
2012-10-01
..., symbol, or other identifying particular assigned to the individual; (e) System record means a group of... U.S. Commission on Civil Rights; (b) Individual means a citizen of the United States or an alien...) Record means any item, collection, or grouping of information about an individual that is maintained by...
Code of Federal Regulations, 2013 CFR
2013-10-01
..., symbol, or other identifying particular assigned to the individual; (e) System record means a group of... U.S. Commission on Civil Rights; (b) Individual means a citizen of the United States or an alien...) Record means any item, collection, or grouping of information about an individual that is maintained by...
DNATCO: assignment of DNA conformers at dnatco.org.
Černý, Jiří; Božíková, Paulína; Schneider, Bohdan
2016-07-08
The web service DNATCO (dnatco.org) classifies local conformations of DNA molecules beyond their traditional sorting to A, B and Z DNA forms. DNATCO provides an interface to robust algorithms assigning conformation classes called NTC: to dinucleotides extracted from DNA-containing structures uploaded in PDB format version 3.1 or above. The assigned dinucleotide NTC: classes are further grouped into DNA structural alphabet NTA: , to the best of our knowledge the first DNA structural alphabet. The results are presented at two levels: in the form of user friendly visualization and analysis of the assignment, and in the form of a downloadable, more detailed table for further analysis offline. The website is free and open to all users and there is no login requirement. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.
Boyd, B M; Shackelford, S D; Hales, K E; Brown-Brandl, T M; Bremer, M L; Spangler, M L; Wheeler, T L; King, D A; Erickson, G E
2015-12-01
Steers ( = 480; 22% with black hides and 78% with red hides) were used to study the effects of shade and feeding zilpaterol hydrochloride (ZH) on performance, carcass quality, heat stress, mobility, and body temperature (BT). A randomized block design with a 2 × 2 factorial treatment arrangement was used with 4 replicates per treatment. Factors included housing type (open or shaded pens) and the feeding of ZH (0 or 8.33 mg/kg DM) the last 21 d on feed with a 3-d withdrawal. Cattle were blocked by BW into a heavy or light block and randomly assigned to pen within each block. Rumen boluses to record BT were inserted before ZH feeding. Respiration rate and panting scores were recorded daily during the ZH feeding period. Mobility scores were collected at various time points from before ZH feeding through harvest. Interactions between ZH and housing type were not significant ( > 0.26) for animal performance, carcass characteristics, and respiration or panting score. No differences ( > 0.44) were observed for DMI, ADG, or G:F on a live basis due to ZH; however, cattle fed in open pens tended ( = 0.08) to have a greater ADG than cattle in shaded pens. Cattle fed ZH had 14 kg heavier carcasses with larger LM area ( < 0.01) than control cattle. Respiration rates for cattle fed ZH were greater ( = 0.05) with no differences ( = 0.88) due to housing. Time affected ( < 0.01) mobility scores, with observations on the morning of harvest at the abattoir being the worst for all groups of cattle. An interaction ( < 0.01) was observed between ZH and housing type for BT. Cattle fed ZH, in both shaded and open pens, had lower ( < 0.05) average, maximum, and area under the curve BT than control cattle fed in the same housing type. However, the observed reduction in BT due to ZH was greater for cattle fed ZH in open pens than for cattle fed ZH in shaded pens. From these results, we conclude that ZH improved HCW with little impact on heat stress or mobility, suggesting that animal welfare was not affected by feeding ZH for 21 d at the end of the feeding period.
Accuracy of recorded tumor, node, and metastasis stage in a comprehensive cancer center.
Brierley, James D; Catton, Pamela A; O'Sullivan, Brian; Dancey, Janet E; Dowling, Anthony J; Irish, Jonathan C; McGowan, Thomas S; Sturgeon, Jeremy F G; Swallow, Carol J; Rodrigues, George B; Panzarella, Tony
2002-01-15
The benefits of recording the tumor, node, and metastasis (TNM) stages of cancer patients are well accepted, but little is known about how accurately this is performed. An audit was performed to determine the accuracy of recorded stage and to act as a baseline before the implementation of an education program. All new patient referrals to Princess Margaret Hospital between July 1 and August 31, 1997, were reviewed. An audit panel composed of five health record technicians (HRTs) and 10 doctors was assembled. Each auditor reviewed 10% of the health record. If there was a discrepancy between the stage in the health record and the auditor stage, then the final stage was determined by the audit committee. Analysis of the agreement between the health record, the physician auditor, the HRT auditor, and the final stage was performed. A total of 855 patients were referred with a new diagnosis of a malignancy for which there was a TNM stage system; 833 patients (97.4%) had a stage assigned. There was agreement between the health record stage and final stage in 80% (95% confidence interval [CI], 77% to 82%) of cases for clinical stage, compared with 90% (95% CI, 87% to 92%) for pathologic stage. Of the major site groups, lung was the least accurately recorded. The most common major discrepancies were due to the recording of X when a definite category could be assigned. This audit demonstrates the importance of staging and provides impetus to develop staging guidelines and education programs.
Sleep pattern and locomotor activity are impaired by doxorubicin in non-tumor-bearing rats.
Lira, Fabio Santos; Esteves, Andrea Maculano; Pimentel, Gustavo Duarte; Rosa, José Cesar; Frank, Miriam Kannebley; Mariano, Melise Oliveira; Budni, Josiane; Quevedo, João; Santos, Ronaldo Vagner Dos; de Mello, Marco Túlio
2016-01-01
We sought explore the effects of doxorubicin on sleep patterns and locomotor activity. To investigate these effects, two groups were formed: a control group and a Doxorubicin (DOXO) group. Sixteen rats were randomly assigned to either the control or DOXO groups. The sleep patterns were examined by polysomnographic recording and locomotor activity was evaluated in an open-field test. In the light period, the total sleep time and slow wave sleep were decreased, while the wake after sleep onset and arousal were increased in the DOXO group compared with the control group (p<0.05). In the dark period, the total sleep time, arousal, and slow wave sleep were increased, while the wake after sleep onset was decreased in the DOXO group compared with the control group (p<0.05). Moreover, DOXO induced a decrease of crossing and rearing numbers when compared control group (p<0.05). Therefore, our results suggest that doxorubicin induces sleep pattern impairments and reduction of locomotor activity.
Radiocarbon analysis of halophilic microbial lipids from an Australian salt lake
NASA Astrophysics Data System (ADS)
Bray, P. Sargent; Jones, Claudia M.; Fallon, Stewart J.; Brocks, Jochen J.; George, Simon C.
2012-01-01
Assigning accurate dates to hypersaline sediments opens important terrestrial records of local and regional paleoecologies and paleoclimatology. However, as of yet no conventional method of dating hypersaline systems has been widely adopted. Biomarker, mineralogical, and radiocarbon analyses of sediments and organic extracts from a shallow (13 cm) core from a hypersaline playa, Lake Tyrrell, southeastern Australia, produce a coherent age-depth curve beginning with modern microbial mats and extending to ~ 7500 cal yr BP. These analyses are furthermore used to identify and constrain the timing of the most recent change in hydrological regime at Lake Tyrrell, a shift from a clay deposit to the precipitation of evaporitic sands occurring at some time between ~ 4500 and 7000 yr. These analyses show the potential for widespread dating of hypersaline systems integrating the biomarker approach, reinforce the value of the radiocarbon content of biomarkers in understanding the flow of carbon in modern ecologies, and validate the temporal dimension of data provided by biomarkers when dating late Quaternary sediments.
Generalized Criteria and Evaluation Method for Center of Excellence: A Preliminary Report
2009-12-01
center of excellence for the domain MIMOSA . 1 As part of the establishment, AMRDEC SED recommended that each such organization be required to be...Information Management Open Systems Alliance ( MIMOSA ) is a not-for-profit trade association dedicated to developing and encouraging the adoption of open...focused on a specific domain— MIMOSA , for example. Rather, these characteristics are described in terms of assigned mission area, thereby being
Niklasson, Markus; Ahlner, Alexandra; Andresen, Cecilia; Marsh, Joseph A; Lundström, Patrik
2015-01-01
The process of resonance assignment is fundamental to most NMR studies of protein structure and dynamics. Unfortunately, the manual assignment of residues is tedious and time-consuming, and can represent a significant bottleneck for further characterization. Furthermore, while automated approaches have been developed, they are often limited in their accuracy, particularly for larger proteins. Here, we address this by introducing the software COMPASS, which, by combining automated resonance assignment with manual intervention, is able to achieve accuracy approaching that from manual assignments at greatly accelerated speeds. Moreover, by including the option to compensate for isotope shift effects in deuterated proteins, COMPASS is far more accurate for larger proteins than existing automated methods. COMPASS is an open-source project licensed under GNU General Public License and is available for download from http://www.liu.se/forskning/foass/tidigare-foass/patrik-lundstrom/software?l=en. Source code and binaries for Linux, Mac OS X and Microsoft Windows are available.
Niklasson, Markus; Ahlner, Alexandra; Andresen, Cecilia; Marsh, Joseph A.; Lundström, Patrik
2015-01-01
The process of resonance assignment is fundamental to most NMR studies of protein structure and dynamics. Unfortunately, the manual assignment of residues is tedious and time-consuming, and can represent a significant bottleneck for further characterization. Furthermore, while automated approaches have been developed, they are often limited in their accuracy, particularly for larger proteins. Here, we address this by introducing the software COMPASS, which, by combining automated resonance assignment with manual intervention, is able to achieve accuracy approaching that from manual assignments at greatly accelerated speeds. Moreover, by including the option to compensate for isotope shift effects in deuterated proteins, COMPASS is far more accurate for larger proteins than existing automated methods. COMPASS is an open-source project licensed under GNU General Public License and is available for download from http://www.liu.se/forskning/foass/tidigare-foass/patrik-lundstrom/software?l=en. Source code and binaries for Linux, Mac OS X and Microsoft Windows are available. PMID:25569628
Validation of a general practice audit and data extraction tool.
Peiris, David; Agaliotis, Maria; Patel, Bindu; Patel, Anushka
2013-11-01
We assessed how accurately a common general practitioner (GP) audit tool extracts data from two software systems. First, pathology test codes were audited at 33 practices covering nine companies. Second, a manual audit of chronic disease data from 200 random patient records at two practices was compared with audit tool data. Pathology review: all companies assigned correct codes for cholesterol, creatinine and glycated haemoglobin; four companies assigned incorrect codes for albuminuria tests, precluding accurate detection with the audit tool. Case record review: there was strong agreement between the manual audit and the tool for all variables except chronic kidney disease diagnoses, which was due to a tool-related programming error. The audit tool accurately detected most chronic disease data in two GP record systems. The one exception, however, highlights the importance of surveillance systems to promptly identify errors. This will maximise potential for audit tools to improve healthcare quality.
Infant behavioral responses to infant-directed singing and other maternal interactions.
de l'Etoile, Shannon K
2006-07-01
Seventy, 6-9-month-old infants were videotaped during six interactions: mother sings assigned song, "stranger" sings assigned song, mother sings song of choice, mother reads book, mother plays with toy, and mother and infant listen to recorded music. Infant-directed (ID) singing conditions elicited moderately positive cognitive behavior, low levels of positive physical behavior and minimal amounts of vocal behaviors, mostly negative. Across all conditions, cognitive scores remained positive at low to moderate levels. Physical responses were most positive during book and toy, most negative during recorded music, and differed by gender, especially during ID singing. Vocally, infants responded positively to toy, and 8-month-old infants vocalized more than younger infants, particularly during ID singing conditions. ID singing appears just as effective as book reading or toy play in sustaining infant attention and far more effective than listening to recorded music, while interactions involving objects may provide opportunity for shared attention.
ERIC Educational Resources Information Center
Sugranes, Maria R.; Snider, Larry C.
1985-01-01
Describes the development of an automated library instruction records management system using microcomputer technology. Development described includes assessment of need, exploration of options, system design, and operational development. System products are identified and operational results are reported based on actual system performance.…
28 CFR 31.203 - Open meetings and public access to records.
Code of Federal Regulations, 2014 CFR
2014-07-01
... their functions. Juvenile Justice Act Requirements ... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Open meetings and public access to records. 31.203 Section 31.203 Judicial Administration DEPARTMENT OF JUSTICE OJJDP GRANT PROGRAMS Formula...
28 CFR 31.203 - Open meetings and public access to records.
Code of Federal Regulations, 2010 CFR
2010-07-01
... their functions. Juvenile Justice Act Requirements ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Open meetings and public access to records. 31.203 Section 31.203 Judicial Administration DEPARTMENT OF JUSTICE OJJDP GRANT PROGRAMS Formula...
28 CFR 31.203 - Open meetings and public access to records.
Code of Federal Regulations, 2012 CFR
2012-07-01
... their functions. Juvenile Justice Act Requirements ... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Open meetings and public access to records. 31.203 Section 31.203 Judicial Administration DEPARTMENT OF JUSTICE OJJDP GRANT PROGRAMS Formula...
28 CFR 31.203 - Open meetings and public access to records.
Code of Federal Regulations, 2011 CFR
2011-07-01
... their functions. Juvenile Justice Act Requirements ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Open meetings and public access to records. 31.203 Section 31.203 Judicial Administration DEPARTMENT OF JUSTICE OJJDP GRANT PROGRAMS Formula...
28 CFR 31.203 - Open meetings and public access to records.
Code of Federal Regulations, 2013 CFR
2013-07-01
... their functions. Juvenile Justice Act Requirements ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Open meetings and public access to records. 31.203 Section 31.203 Judicial Administration DEPARTMENT OF JUSTICE OJJDP GRANT PROGRAMS Formula...
The effect of public disclosure laws on biomedical research.
Cardon, Andrew D; Bailey, Matthew R; Bennett, B Taylor
2012-05-01
The Freedom of Information Act (FOIA) and state 'open-records' laws govern access to records in the possession of federal agencies and state entities, such as public universities. Although these laws are intended to promote 'open government' and to assure the existence of an informed citizenry capable of holding government officials accountable for their decisions, an inherent tension exists between the public's access to information and biomedical research institutions' need to ensure the confidentiality of proprietary records and to protect the personal safety of employees. Recognizing these and other conflicts, the federal FOIA and state public-disclosure laws contain express exemptions to protect sensitive information from disclosure. Although some state open-records laws are modeled after the federal FOIA, important differences exist based on the language used by the state law, court interpretations, and exemptions. Two specific types of exemptions are particularly relevant to research facilities: exemptions for research information and exemptions for personal information. Responding to FOIA and state open-records requests requires knowledge of relevant laws and the involvement of all interested parties to facilitate a coordinated and orderly response.
Cost-benefit of a clinical services integrated with a decentralized unit dose system.
Warrian, K; Irvine-Meek, J
1988-06-01
Clinical pharmacy services are believed to be beneficial to patient care and to have the potential to reduce drug costs. This study was designed to apply cost-benefit analysis techniques to selected clinical pharmacy services provided by staff pharmacists assigned to a mobile decentralized unit-dose drug distribution system. Pharmacists' interventions were identified and recorded by the pharmacists and the investigator over an eight-week period. Interventions, to which a monetary value could be assigned, included non-formulary drug use, drug regimen adjustments, and the duration of drug therapy. A total of 543 interventions were recorded or observed. Of these, 174 (32 percent) fit the criteria for inclusion in the study. Those interventions accepted by physicians (87 percent) were assigned a dollar value and tabulated. Costs to provide the service were the pharmacists' salaries. Benefit to cost ratios of 1.08 and 1.59 demonstrated that the benefits accrued from selected clinical pharmacy services exceeded the costs to the hospital.
Multiple murder and criminal careers: a latent class analysis of multiple homicide offenders.
Vaughn, Michael G; DeLisi, Matt; Beaver, Kevin M; Howard, Matthew O
2009-01-10
To construct an empirically rigorous typology of multiple homicide offenders (MHOs). The current study conducted latent class analysis of the official records of 160 MHOs sampled from eight states to evaluate their criminal careers. A 3-class solution best fit the data (-2LL=-1123.61, Bayesian Information Criterion (BIC)=2648.15, df=81, L(2)=1179.77). Class 1 (n=64, class assignment probability=.999) was the low-offending group marked by little criminal record and delayed arrest onset. Class 2 (n=51, class assignment probability=.957) was the severe group that represents the most violent and habitual criminals. Class 3 (n=45, class assignment probability=.959) was the moderate group whose offending careers were similar to Class 2. A sustained criminal career with involvement in versatile forms of crime was observed for two of three classes of MHOs. Linkages to extant typologies and recommendations for additional research that incorporates clinical constructs are proffered.
NASA Technical Reports Server (NTRS)
Lee, Timothy J.; Arnold, James O. (Technical Monitor)
1994-01-01
A new spin orbital basis is employed in the development of efficient open-shell coupled-cluster and perturbation theories that are based on a restricted Hartree-Fock (RHF) reference function. The spin orbital basis differs from the standard one in the spin functions that are associated with the singly occupied spatial orbital. The occupied orbital (in the spin orbital basis) is assigned the delta(+) = 1/square root of 2(alpha+Beta) spin function while the unoccupied orbital is assigned the delta(-) = 1/square root of 2(alpha-Beta) spin function. The doubly occupied and unoccupied orbitals (in the reference function) are assigned the standard alpha and Beta spin functions. The coupled-cluster and perturbation theory wave functions based on this set of "symmetric spin orbitals" exhibit much more symmetry than those based on the standard spin orbital basis. This, together with interacting space arguments, leads to a dramatic reduction in the computational cost for both coupled-cluster and perturbation theory. Additionally, perturbation theory based on "symmetric spin orbitals" obeys Brillouin's theorem provided that spin and spatial excitations are both considered. Other properties of the coupled-cluster and perturbation theory wave functions and models will be discussed.
ERIC Educational Resources Information Center
Gurfinkel, Debbie M.; Wolever, Thomas M. S.
2017-01-01
The completion of a 3-d food record, using commonly available nutrient analysis software, is a typical assignment for students in nutrition and food science programs. While these assignments help students evaluate their personal diets, it is insufficient to teach students about surveys of large population cohorts. This paper shows how the Test,…
Charles W. McHugh; Paul Gleason
2003-01-01
The purpose of this report is to document the suppression actions taken during the Hayman Fire. The long duration of suppression activities (June 8 through July 18), and multiple incident management teams assigned to the fire, makes this a challenging task. Original records and reports produced independently by the various teams assigned to different portions of the...
NASA Astrophysics Data System (ADS)
Mikhailenko, S. N.; Leshchishina, O.; Karlovets, E. V.; Mondelain, D.; Kassi, S.; Campargue, A.
2016-07-01
The room temperature absorption spectrum of water vapor highly enriched in 17O has been recorded by Cavity Ring Down Spectroscopy (CRDS) between 5850 and 6671 cm-1. Two series of recordings were performed with pressure values of 1.0 and 12.0 Torr. The investigated spectral region corresponds to the important 1.55 μm transparency window of the atmosphere where water absorption is very weak. The high sensitivity of the recordings (αmin 5×10-11 cm-1) allows detecting lines with intensity spanning six orders of magnitude (1.4×10-30-3.6×10-24 cm/molecule at room temperature). The experimental list includes more than 10,300 lines. The assignments of water lines were performed using known experimental energy levels as well as calculated line lists based on the results of Partridge and Schwenke. More than 8500 lines were assigned to 9619 transitions of six water isotopologues (H216O, H217O, H218O, HD16O, HD17O and HD18O). All but four transitions of the 16O and 18O isotopologues were assigned using known experimental energy levels. More than half of the assigned H217O and HD17O transitions correspond to new (or corrected) upper energy levels. About 1000 new H217O transitions associated with upper states of the second triad and of the first hexad were identified. Most of the newly assigned HD17O transitions belong to the ν1+ν3 and 2ν2+ν3 bands. The assigned transitions allowed to newly determine or correct 20 highly excited rotational levels of the vibrational ground state of this isotopologue. Overall 791 and 266 energy levels are newly determined for H217O and HD17O, respectively. A few additional levels were corrected compared to literature values. The obtained experimental results are compared to the spectroscopic parameters provided by the HITRAN database and to the empirical energy levels recommended by an IUPAC task group.
Pathak, Garima; Upadhyay, Amit; Pathak, Umesh; Chawla, Deepak; Goel, Sneh P
2013-08-01
To compare the efficacy of phenobarbitone and phenytoin for treatment of neonatal seizures in term and near-term neonates. Open labeled randomized controlled trial. Neonatal intensive care unit of a level II unit from India, from November 2008 to September 2009. All term and late pre-term neonates admitted with clinically apparent seizures and not having any transient metabolic disorders (hypoglycemia or hypocalcemia) were randomly assigned. Phenobarbitone (n=54) or phenytoin (n=55) intravenously 20 mg/kg/dose over 20-30 min. Neonates whose seizures were not controlled by the assigned drug were then crossed over to be treated with other drug in same dose. Clinical control of seizures (seizure free period of 24 hours after giving anticonvulsant). Baseline characteristics including mean birthweight, gestation age and sex were comparable in both groups. Seizures were controlled in 8 of the 55 (14.5%) neonates who received phenytoin, as compared to 39 of 54 (72.2%) neonates who received phenobarbitone (P <0.001). In babies not responding to assigned drugs, after cross-over to the other drug, seizure control was achieved in 44/55 (80%) of the neonates assigned to receive phenytoin first as compared to 49/54 (91%) of those assigned to receive phenobarbitone first (P=0.014). After maximum dose of phenobarbitone seizures were controlled in 49/55(89%) in phenytoin group and 52/54 (96%) in phenobarbitone group (P<0.05). Phenobarbitone is more efficacious than phenytoin in control of clinical seizures in term or near-term neonates, irrespective of etiology. To evaluate serum vascular endothelial growth factor (VEGF) levels in children with acute lymphoblastic leukemia (ALL) during the induction phase of chemotherapy.
Yao, James C; Pavel, Marianne; Lombard-Bohas, Catherine; Van Cutsem, Eric; Voi, Maurizio; Brandt, Ulrike; He, Wei; Chen, David; Capdevila, Jaume; de Vries, Elisabeth G E; Tomassetti, Paola; Hobday, Timothy; Pommier, Rodney; Öberg, Kjell
2016-11-10
Purpose Everolimus improved median progression-free survival by 6.4 months in patients with advanced pancreatic neuroendocrine tumors (NET) compared with placebo in the RADIANT-3 study. Here, we present the final overall survival (OS) data and data on the impact of biomarkers on OS from the RADIANT-3 study. Methods Patients with advanced, progressive, low- or intermediate-grade pancreatic NET were randomly assigned to everolimus 10 mg/day (n = 207) or placebo (n = 203). Crossover from placebo to open-label everolimus was allowed on disease progression. Ongoing patients were unblinded after final progression-free survival analysis and could transition to open-label everolimus at the investigator's discretion (extension phase). OS analysis was performed using a stratified log-rank test in the intent-to-treat population. The baseline levels of chromogranin A, neuron-specific enolase, and multiple soluble angiogenic biomarkers were determined and their impact on OS was explored. Results Of 410 patients who were enrolled between July 2007 and March 2014, 225 received open-label everolimus, including 172 patients (85%) randomly assigned initially to the placebo arm. Median OS was 44.0 months (95% CI, 35.6 to 51.8 months) for those randomly assigned to everolimus and 37.7 months (95% CI, 29.1 to 45.8 months) for those randomly assigned to placebo (hazard ratio, 0.94; 95% CI, 0.73 to 1.20; P = .30). Elevated baseline chromogranin A, neuron-specific enolase, placental growth factor, and soluble vascular endothelial growth factor receptor 1 levels were poor prognostic factors for OS. The most common adverse events included stomatitis, rash, and diarrhea. Conclusion Everolimus was associated with a median OS of 44 months in patients with advanced, progressive pancreatic NET, the longest OS reported in a phase III study for this population. Everolimus was associated with a survival benefit of 6.3 months, although this finding was not statistically significant. Crossover of patients likely confounded the OS results.
DOE Office of Scientific and Technical Information (OSTI.GOV)
WESTRICH, HENRY; WILSON, ANDREW; STANTON, ERIC
LDRDView is a software tool for visualizing a collection of textual records and exploring relationships between them for the purpose of gaining new insights about the submitted information. By evaluating the content of the records and assigning coordinates to each based on its similarity to others, LDRDView graphically displays a corpus of records either as a landscape of hills and valleys or as a graph of nodes and links. A suite of data analysis tools facilitates in-depth exploration of the corpus as a whole and the content of each individual record.
ERIC Educational Resources Information Center
Kolovelonis, Athanasios; Goudas, Marios; Dermitzaki, Irini
2011-01-01
This study examined the effect of different goals (process, performance outcome, and multiple goals) and self-recording on self-regulation of learning a dart-throwing skill. Participants were 105 fifth and sixth graders who were randomly assigned to six (3 Goal type x 2 self-recording) experimental and one control group. Results showed a positive…
ORBDA: An openEHR benchmark dataset for performance assessment of electronic health record servers.
Teodoro, Douglas; Sundvall, Erik; João Junior, Mario; Ruch, Patrick; Miranda Freire, Sergio
2018-01-01
The openEHR specifications are designed to support implementation of flexible and interoperable Electronic Health Record (EHR) systems. Despite the increasing number of solutions based on the openEHR specifications, it is difficult to find publicly available healthcare datasets in the openEHR format that can be used to test, compare and validate different data persistence mechanisms for openEHR. To foster research on openEHR servers, we present the openEHR Benchmark Dataset, ORBDA, a very large healthcare benchmark dataset encoded using the openEHR formalism. To construct ORBDA, we extracted and cleaned a de-identified dataset from the Brazilian National Healthcare System (SUS) containing hospitalisation and high complexity procedures information and formalised it using a set of openEHR archetypes and templates. Then, we implemented a tool to enrich the raw relational data and convert it into the openEHR model using the openEHR Java reference model library. The ORBDA dataset is available in composition, versioned composition and EHR openEHR representations in XML and JSON formats. In total, the dataset contains more than 150 million composition records. We describe the dataset and provide means to access it. Additionally, we demonstrate the usage of ORBDA for evaluating inserting throughput and query latency performances of some NoSQL database management systems. We believe that ORBDA is a valuable asset for assessing storage models for openEHR-based information systems during the software engineering process. It may also be a suitable component in future standardised benchmarking of available openEHR storage platforms.
ORBDA: An openEHR benchmark dataset for performance assessment of electronic health record servers
Sundvall, Erik; João Junior, Mario; Ruch, Patrick; Miranda Freire, Sergio
2018-01-01
The openEHR specifications are designed to support implementation of flexible and interoperable Electronic Health Record (EHR) systems. Despite the increasing number of solutions based on the openEHR specifications, it is difficult to find publicly available healthcare datasets in the openEHR format that can be used to test, compare and validate different data persistence mechanisms for openEHR. To foster research on openEHR servers, we present the openEHR Benchmark Dataset, ORBDA, a very large healthcare benchmark dataset encoded using the openEHR formalism. To construct ORBDA, we extracted and cleaned a de-identified dataset from the Brazilian National Healthcare System (SUS) containing hospitalisation and high complexity procedures information and formalised it using a set of openEHR archetypes and templates. Then, we implemented a tool to enrich the raw relational data and convert it into the openEHR model using the openEHR Java reference model library. The ORBDA dataset is available in composition, versioned composition and EHR openEHR representations in XML and JSON formats. In total, the dataset contains more than 150 million composition records. We describe the dataset and provide means to access it. Additionally, we demonstrate the usage of ORBDA for evaluating inserting throughput and query latency performances of some NoSQL database management systems. We believe that ORBDA is a valuable asset for assessing storage models for openEHR-based information systems during the software engineering process. It may also be a suitable component in future standardised benchmarking of available openEHR storage platforms. PMID:29293556
ERIC Educational Resources Information Center
Journal of Reading, 1987
1987-01-01
Recounts the use of: (1) a game of reading trivia to review a unit in reading, (2) a reading-related art activity that emphasized the importance of following directions, and (3) the assignment of a research paper in a remedial curriculum. (NKA)
2017-01-24
Objectives: Open surgical reconstruction using expanded polytetrafluoroethylene stent grafts to create a sutureless anastomosis is an alternative to...French Argyle shunt was inserted into one randomly assigned artery, with a self-expanding ePTFE stent deployed in the other. Arterial flow measurements...for histopathology were obtained during the terminal procedure. Results: Angiography revealed no difference in patency at 72 hours. The stent grafts
NOAA - National Oceanic and Atmospheric Administration - Significant Ozone
RESEARCH COASTS CAREERS National Oceanic and Atmospheric Administration, United States Department of smallest since 1986. The record low of 89 DU was recorded on Oct. 6, 1993. The atmospheric ozone layer nearly completed a year-long assignment at South Pole Station where they collect atmospheric data and
CTEPP STANDARD OPERATING PROCEDURE FOR HANDLING SAMPLE AND DATA CUSTODY (SOP-2.26)
This SOP describes the method for handling sample custody. A standardized Chain-of-Custody (CoC) Record is used to document the sample/data custody. Each participant is assigned one CoC Record for the samples/data collected at their home and/or day care center.
The role of high-level calculations in the assignment of the Q-band spectra of chlorophyll
DOE Office of Scientific and Technical Information (OSTI.GOV)
Reimers, Jeffrey R.; Cai, Zheng-Li; Kobayashi, Rika
2014-10-06
We recently established a novel assignment of the visible absorption spectrum of chlorophyll-a that sees the two components Q{sub x} and Q{sub y} of the low-energy Q band as being intrinsically mixed by non-adiabatic coupling. This ended 50 years debate as to the nature of the Q bands, with prior discussion poised only in the language of the Born-Oppenheimer and Condon approximations. The new assignment presents significant ramifications for exciton transport and quantum coherence effects in photosystems. Results from state of the art electronic structure calculations have always been used to justify assignments, but quantitative inaccuracies and systematic failures havemore » historically limited usefulness. We examine the role of CAM-B3LYP time-dependent density-functional theory (TD-DFT) and Symmetry Adapted Cluster-Configuration Interaction (SAC-CI) calculations in first showing that all previous assignments were untenable, in justifying the new assignment, in making some extraordinary predictions that were vindicated by the new assignment, and in then identifying small but significant anomalies in the extensive experimental data record.« less
Seif, Gretchen A; Brown, Debora
2013-01-01
It is difficult to provide real-world learning experiences for students to master clinical and communication skills. The purpose of this paper is to describe a novel instructional method using self- and peer-assessment, reflection, and technology to help students develop effective interpersonal and clinical skills. The teaching method is described by the constructivist learning theory and incorporates the use of educational technology. The learning activities were incorporated into the pre-clinical didactic curriculum. The students participated in two video-recording assignments and performed self-assessments on each and had a peer-assessment on the second video-recording. The learning activity was evaluated through the self- and peer-assessments and an instructor-designed survey. This evaluation identified several themes related to the assignment, student performance, clinical behaviors and establishing rapport. Overall the students perceived that the learning activities assisted in the development of clinical and communication skills prior to direct patient care. The use of video recordings of a simulated history and examination is a unique learning activity for preclinical PT students in the development of clinical and communication skills.
Manns, Michael; Pol, Stanislas; Jacobson, Ira M; Marcellin, Patrick; Gordon, Stuart C; Peng, Cheng-Yuan; Chang, Ting-Tsung; Everson, Gregory T; Heo, Jeong; Gerken, Guido; Yoffe, Boris; Towner, William J; Bourliere, Marc; Metivier, Sophie; Chu, Chi-Jen; Sievert, William; Bronowicki, Jean-Pierre; Thabut, Dominique; Lee, Youn-Jae; Kao, Jia-Horng; McPhee, Fiona; Kopit, Justin; Mendez, Patricia; Linaberry, Misti; Hughes, Eric; Noviello, Stephanie
2014-11-01
An unmet need exists for interferon-free and ribavirin-free treatments for chronic hepatitis C virus (HCV) infection. In this study, we assessed all-oral therapy with daclatasvir (NS5A replication complex inhibitor) plus asunaprevir (NS3 protease inhibitor) in patients with genotype 1b infection, including those with high unmet needs or cirrhosis, or both. We did this phase 3, multicohort study (HALLMARK-DUAL) at 116 sites in 18 countries between May 11, 2012, and Oct 9, 2013. Patients were adults with chronic HCV genotype 1b infection who were treatment-naive; previous non-responders to peginterferon alfa plus ribavirin; or medically ineligible for, previously intolerant of, or ineligible for and intolerant of peginterferon alfa plus ribavirin. Treatment-naive patients were randomly assigned (2:1 ratio) by an interactive voice-response system with a computer-generated random allocation sequence (stratified by cirrhosis status) to receive daclatasvir 60 mg once daily plus asunaprevir 100 mg twice daily or placebo for 12 weeks. Patients and investigator sites were masked to treatment assignment and HCV RNA results to the end of week 12. The treatment-naive group assigned to daclatasvir plus asunaprevir continued open-label treatment to the end of week 24; participants assigned to placebo entered another daclatasvir plus asunaprevir study. Non-responders and ineligible, intolerant, or ineligible and intolerant patients received open-label daclatasvir plus asunaprevir for 24 weeks. The primary endpoint was sustained virological response at post-treatment week 12. Efficacy analyses were restricted to patients given daclatasvir plus asunaprevir. This trial is registered with ClinicalTrials.gov, number NCT01581203. This study included 307 treatment-naive patients (205 received daclatasvir plus asunaprevir and 102 received placebo; all randomly assigned patients received the intended treatment), 205 non-responders, and 235 ineligible, intolerant, or ineligible and intolerant patients. Daclatasvir plus asunaprevir provided sustained virological response in 182 (90%, 95% CI 85-94) patients in the treatment-naive cohort, 168 (82%, 77-87) in the non-responder cohort, and 192 (82%, 77-87) in the ineligible, intolerant, or ineligible and intolerant cohort. Serious adverse events occurred in 12 (6%) patients in the treatment-naive group; 11 (5%) non-responders, and 16 (7%) ineligible, intolerant, or ineligible and intolerant patients; adverse events leading to discontinuation (most commonly reversible increases in alanine or aspartate aminotransferase) occurred in six (3%), two (1%), and two (1%) patients, respectively, with no deaths recorded. Grade 3 or 4 laboratory abnormalities were uncommon, with low incidences of aminotransferase increases during the first 12 weeks with daclatasvir plus asunaprevir and placebo in treatment-naive patients (≤2% each). Daclatasvir plus asunaprevir provided high sustained virological response rates in treatment-naive, non-responder, and ineligible, intolerant, or ineligible and intolerant patients, and was well tolerated in patients with HCV genotype 1b infection. These results support the use of daclatasvir plus asunaprevir as an all-oral, interferon-free and ribavirin-free treatment option for patients with HCV genotype 1b infection, including those with cirrhosis. Bristol-Myers Squibb. Copyright © 2014 Elsevier Ltd. All rights reserved.
Single-tier city logistics model for single product
NASA Astrophysics Data System (ADS)
Saragih, N. I.; Nur Bahagia, S.; Suprayogi; Syabri, I.
2017-11-01
This research develops single-tier city logistics model which consists of suppliers, UCCs, and retailers. The problem that will be answered in this research is how to determine the location of UCCs, to allocate retailers to opened UCCs, to assign suppliers to opened UCCs, to control inventory in the three entities involved, and to determine the route of the vehicles from opened UCCs to retailers. This model has never been developed before. All the decisions will be simultaneously optimized. Characteristic of the demand is probabilistic following a normal distribution, and the number of product is single.
Fotie, Jean; Kemami Wangun, Hilaire V; Dreux, Katelyn; Sommerfeld, Thomas; Pittman, Jacob
2012-01-01
Because of their extreme instability, it is generally difficult to synthesize and fully characterize open chain peroxides, also known as peroxols. In our attempt to investigate the mechanism of the Skraup-Doebner-Von Miller quinoline synthesis, we were able to obtain an unusual open chain peroxy-quinoline, namely, 4-(8-ethoxy-2,3-dihydro-1H-cyclopenta[c]quinolin-4-yl)butane-1-peroxol (1), and its alcohol counterpart, namely 4-(8-ethoxy-2,3-dihydro-1H-cyclopenta[c]quinolin-4-yl)butan-1-ol (2) obtained as a side product during the same reaction. Although structurally similar, these two compounds appeared to display some very distinct physical and spectroscopic characteristics. This work reports detailed NMR studies and full (1) H and (13) C NMR assignments for these two compounds. These assignments are based upon the analysis of the NMR spectra of these compounds including (1) H, (13) C, COSY, gHSQC and gHMBC. The effect of the peroxide functional group on the chemical shift of neighboring carbons and protons was also investigated by comparing the NMR data of these two compounds. Furthermore, the effects of potential hydrogen bondings in 1, 2, and possible 1-1 dimer, 2-2 dimer and in prototypical model systems, as well as the stability of these compounds, were investigated computationally. The computed dissociation energies and NMR data support the interpretation of the experimental data. Copyright © 2012 John Wiley & Sons, Ltd.
NASA Technical Reports Server (NTRS)
Bragin, J.; Diem, M.; Guthals, D.; Chang, S.
1977-01-01
The infrared spectra of alkali metal and ammonium hydrosulfides have been recorded from wavenumbers of 200 to 4000 at liquid nitrogen temperatures, and the Raman spectra of these substances have been recorded from wavenumbers of 0 to 4000 over the temperature range 83-390 K. No evidence of a second solid phase was obtained. Internal and external fundamentals were assigned, in detail, based on selection rules, isotopic frequency shifts, and analogy with structurally similar salts. Barriers to anion and cation reorientation of 3.8 and 1.9 kcal/mole, respectively, have been calculated from librational assignments. The implications of the infrared spectrum of ammonium hydrosulfide for the possible spectroscopic detection of this substance in the atmosphere of the planet Jupiter are discussed.
MIP models for connected facility location: A theoretical and computational study☆
Gollowitzer, Stefan; Ljubić, Ivana
2011-01-01
This article comprises the first theoretical and computational study on mixed integer programming (MIP) models for the connected facility location problem (ConFL). ConFL combines facility location and Steiner trees: given a set of customers, a set of potential facility locations and some inter-connection nodes, ConFL searches for the minimum-cost way of assigning each customer to exactly one open facility, and connecting the open facilities via a Steiner tree. The costs needed for building the Steiner tree, facility opening costs and the assignment costs need to be minimized. We model ConFL using seven compact and three mixed integer programming formulations of exponential size. We also show how to transform ConFL into the Steiner arborescence problem. A full hierarchy between the models is provided. For two exponential size models we develop a branch-and-cut algorithm. An extensive computational study is based on two benchmark sets of randomly generated instances with up to 1300 nodes and 115,000 edges. We empirically compare the presented models with respect to the quality of obtained bounds and the corresponding running time. We report optimal values for all but 16 instances for which the obtained gaps are below 0.6%. PMID:25009366
Masonry. Progress Record, Theory Outline.
ERIC Educational Resources Information Center
Connecticut State Dept. of Education, Hartford. Div. of Vocational-Technical Schools.
Intended to reduce unnecessary paper work on the part of the shop instructor in a masonry course, this job assignment book offers a simplified method of keeping student records up-to-date. It lists theory objectives and specific objectives for masonry courses in grades 10, 11, and 12. To help the instructor in planning and organizing in advance, a…
Code of Federal Regulations, 2010 CFR
2010-07-01
... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Fees. 323.5 Section 323.5 Money and... TREASURY BUREAU OF THE PUBLIC DEBT DISCLOSURE OF RECORDS § 323.5 Fees. The fees provided in part 1 of title... assignment. (e) Fees may be waived for other classes of requested records upon a finding by the Commissioner...
Jazayeri, Darius; Teich, Jonathan M; Ball, Ellen; Nankubuge, Patricia Alexandra; Rwebembera, Job; Wing, Kevin; Sesay, Alieu Amara; Kanter, Andrew S; Ramos, Glauber D; Walton, David; Cummings, Rachael; Checchi, Francesco; Fraser, Hamish S
2017-01-01
Background Stringent infection control requirements at Ebola treatment centers (ETCs), which are specialized facilities for isolating and treating Ebola patients, create substantial challenges for recording and reviewing patient information. During the 2014-2016 West African Ebola epidemic, paper-based data collection systems at ETCs compromised the quality, quantity, and confidentiality of patient data. Electronic health record (EHR) systems have the potential to address such problems, with benefits for patient care, surveillance, and research. However, no suitable software was available for deployment when large-scale ETCs opened as the epidemic escalated in 2014. Objective We present our work on rapidly developing and deploying OpenMRS-Ebola, an EHR system for the Kerry Town ETC in Sierra Leone. We describe our experience, lessons learned, and recommendations for future health emergencies. Methods We used the OpenMRS platform and Agile software development approaches to build OpenMRS-Ebola. Key features of our work included daily communications between the development team and ground-based operations team, iterative processes, and phased development and implementation. We made design decisions based on the restrictions of the ETC environment and regular user feedback. To evaluate the system, we conducted predeployment user questionnaires and compared the EHR records with duplicate paper records. Results We successfully built OpenMRS-Ebola, a modular stand-alone EHR system with a tablet-based application for infectious patient wards and a desktop-based application for noninfectious areas. OpenMRS-Ebola supports patient tracking (registration, bed allocation, and discharge); recording of vital signs and symptoms; medication and intravenous fluid ordering and monitoring; laboratory results; clinician notes; and data export. It displays relevant patient information to clinicians in infectious and noninfectious zones. We implemented phase 1 (patient tracking; drug ordering and monitoring) after 2.5 months of full-time development. OpenMRS-Ebola was used for 112 patient registrations, 569 prescription orders, and 971 medication administration recordings. We were unable to fully implement phases 2 and 3 as the ETC closed because of a decrease in new Ebola cases. The phase 1 evaluation suggested that OpenMRS-Ebola worked well in the context of the rollout, and the user feedback was positive. Conclusions To our knowledge, OpenMRS-Ebola is the most comprehensive adaptable clinical EHR built for a low-resource setting health emergency. It is designed to address the main challenges of data collection in highly infectious environments that require robust infection prevention and control measures and it is interoperable with other electronic health systems. Although we built and deployed OpenMRS-Ebola more rapidly than typical software, our work highlights the challenges of having to develop an appropriate system during an emergency rather than being able to rapidly adapt an existing one. Lessons learned from this and previous emergencies should be used to ensure that a set of well-designed, easy-to-use, pretested health software is ready for quick deployment in future. PMID:28827211
Reference Manual for the Ada Programming Language
1983-01-01
Convercions 4-21 4.7 Qualified Expresclions 4-24 4.8 Allocators 4-24 4.9 Static Expressions and Static Subtypes 4-26 , 4.10 Universal Expressions 4-27 5...record type.•: • 2 Access types allow the construction of linked data structures created by the evaluation of / allocators . They allow several...the following: A * An assignment (In assignment statements and Initializations), an allocator , a membership test, or a short-circuit control form, * A
NASA Astrophysics Data System (ADS)
Ravazzi, Cesare; Pini, Roberta; Breda, Marzia
2009-12-01
We carried out a systematic investigation on the pollen content of sediment adhering to skeletal elements of large mammals which originate from the long lacustrine record of Leffe (Early Pleistocene of the Italian Alps). Three local faunas were discovered during mining activities along the intermediate part (spanning from 1.5 to 0.95 Ma) of the basin succession. The excellent pollen preservation allowed testing the reproducibility of the pollen signal from single skeletons. A clear palaeoenvironmental patterning, consistent with the ecological preferences of the considered mammal species, emerged from the canonical correspondence analysis of pollen types diagnostic for vegetation communities. Edaphic factors related to seasonal river activity changes and to the development of swamp forests in the riverbanks are significantly associated to the occurrences of Hippopotamus cf. antiquus, whereas finds of Mammuthus meridionalis belong to fully forested landscapes dominated by conifer or mixed forests of oceanic, warm to cool-temperate climate. Rhinoceros habitats include variable forest cover under different climate states. Distinct cool-temperate, partially open vegetation could be recognized for large deer included Cervalces cf carnutorum. A palynostratigraphic correlation between individual spectra and a reference palynostratigraphic record allowed assignment of many fossil remains to a precise stratigraphic position. This procedure also shown that the Leffe local faunas include specimens accumulated under different environmental and climate states, as a consequence of high-frequency climate changes characterizing the Late Villafranchian Early Pleistocene.
Merckaert, Isabelle; Delevallez, France; Gibon, Anne-Sophie; Liénard, Aurore; Libert, Yves; Delvaux, Nicole; Marchal, Serge; Etienne, Anne-Marie; Bragard, Isabelle; Reynaert, Christine; Slachmuylder, Jean-Louis; Scalliet, Pierre; Van Houtte, Paul; Coucke, Philippe; Razavi, Darius
2015-03-10
This study assessed the efficacy of a 38-hour communication skills training program designed to train a multidisciplinary radiotherapy team. Four radiotherapy teams were randomly assigned to a training program or a waiting list. Assessments were scheduled at baseline and after training for the training group and at baseline and 4 months later for the waiting list group. Assessments included an audio recording of a radiotherapy planning session to assess team members' communication skills and expression of concerns of patients with breast cancer (analyzed with content analysis software) and an adapted European Organisation for Research and Treatment of Cancer satisfaction with care questionnaire completed by patients at the end of radiotherapy. Two hundred thirty-seven radiotherapy planning sessions were recorded. Compared with members of the untrained teams, members of the trained teams acquired, over time, more assessment skills (P = .003) and more supportive skills (P = .050) and provided more setting information (P = .010). Over time, patients interacting with members of the trained teams asked more open questions (P = .022), expressed more emotional words (P = .025), and exhibited a higher satisfaction level regarding nurses' interventions (P = .028). The 38-hour training program facilitated transfer of team member learned communication skills to the clinical practice and improved patients' satisfaction with care. © 2015 by American Society of Clinical Oncology.
Hart, Tessa; Hawkey, Karen; Whyte, John
2002-12-01
To test the efficacy of a portable voice organizer in helping people with traumatic brain injury (TBI) to recall therapy goals and plans discussed with their clinical case managers. Prospective within-subjects trial, in which individualized therapy goals were randomly assigned to intervention or no intervention. Comprehensive postacute TBI rehabilitation program. Ten people with moderate to severe TBI enrolled from 3 months to 18 years after injury. Memory for therapy goals. Clinicians generated statements describing six current therapy goals, half of which were randomly assigned to be recorded on a voice organizer during the next case management session. Participants selected three times per day to listen to the recorded goals, prompted by an alarm. One-week recall was tested using both free- and cued-recall formats. Recorded goals were recalled better than unrecorded goals and appeared to be associated with better awareness or follow-through with therapy objectives. Portable electronic devices have the potential to assist with treatment areas beyond tasks involving prospective memory.
Gorrell, Lindsay M; Engel, Roger M; Lystad, Reidar P; Brown, Benjamin T
2017-03-14
Reporting of adverse events in randomized clinical trials (RCTs) is encouraged by the authors of The Consolidated Standards of Reporting Trials (CONSORT) statement. With robust methodological design and adequate reporting, RCTs have the potential to provide useful evidence on the incidence of adverse events associated with spinal manipulative therapy (SMT). During a previous investigation, it became apparent that comprehensive search strategies combining text words with indexing terms was not sufficiently sensitive for retrieving records that were known to contain reports on adverse events. The aim of this analysis was to compare the proportion of articles containing data on adverse events associated with SMT that were indexed in MEDLINE and/or EMBASE and the proportion of those that included adverse event-related words in their title or abstract. A sample of 140 RCT articles previously identified as containing data on adverse events associated with SMT was used. Articles were checked to determine if: (1) they had been indexed with relevant terms describing adverse events in the MEDLINE and EMBASE databases; and (2) they mentioned adverse events (or any related terms) in the title or abstract. Of the 140 papers, 91% were MEDLINE records, 85% were EMBASE records, 81% were found in both MEDLINE and EMBASE records, and 4% were not in either database. Only 19% mentioned adverse event-related text words in the title or abstract. There was no significant difference between MEDLINE and EMBASE records in the proportion of available papers (p = 0.078). Of the 113 papers that were found in both MEDLINE and EMBASE records, only 3% had adverse event-related indexing terms assigned to them in both databases, while 81% were not assigned an adverse event-related indexing term in either database. While there was effective indexing of RCTs involving SMT in the MEDLINE and EMBASE databases, there was a failure of allocation of adverse event indexing terms in both databases. We recommend the development of standardized definitions and reporting tools for adverse events associated with SMT. Adequate reporting of adverse events associated with SMT will facilitate accurate indexing of these types of manuscripts in the databases.
Tanner, Geoffrey R; Lutas, Andrew; Martínez-François, Juan Ramón; Yellen, Gary
2011-06-08
ATP-sensitive potassium channels (K(ATP) channels) are important sensors of cellular metabolic state that link metabolism and excitability in neuroendocrine cells, but their role in nonglucosensing central neurons is less well understood. To examine a possible role for K(ATP) channels in modulating excitability in hippocampal circuits, we recorded the activity of single K(ATP) channels in cell-attached patches of granule cells in the mouse dentate gyrus during bursts of action potentials generated by antidromic stimulation of the mossy fibers. Ensemble averages of the open probability (p(open)) of single K(ATP) channels over repeated trials of stimulated spike activity showed a transient increase in p(open) in response to action potential firing. Channel currents were identified as K(ATP) channels through blockade with glibenclamide and by comparison with recordings from Kir6.2 knock-out mice. The transient elevation in K(ATP) p(open) may arise from submembrane ATP depletion by the Na(+)-K(+) ATPase, as the pump blocker strophanthidin reduced the magnitude of the elevation. Both the steady-state and stimulus-elevated p(open) of the recorded channels were higher in the presence of the ketone body R-β-hydroxybutyrate, consistent with earlier findings that ketone bodies can affect K(ATP) activity. Using perforated-patch recording, we also found that K(ATP) channels contribute to the slow afterhyperpolarization following an evoked burst of action potentials. We propose that activity-dependent opening of K(ATP) channels may help granule cells act as a seizure gate in the hippocampus and that ketone-body-mediated augmentation of the activity-dependent opening could in part explain the effect of the ketogenic diet in reducing epileptic seizures.
Accuracy of external cause-of-injury coding in VA polytrauma patient discharge records.
Carlson, Kathleen F; Nugent, Sean M; Grill, Joseph; Sayer, Nina A
2010-01-01
Valid and efficient methods of identifying the etiology of treated injuries are critical for characterizing patient populations and developing prevention and rehabilitation strategies. We examined the accuracy of external cause-of-injury codes (E-codes) in Veterans Health Administration (VHA) administrative data for a population of injured patients. Chart notes and E-codes were extracted for 566 patients treated at any one of four VHA Polytrauma Rehabilitation Center sites between 2001 and 2006. Two expert coders, blinded to VHA E-codes, used chart notes to assign "gold standard" E-codes to injured patients. The accuracy of VHA E-coding was examined based on these gold standard E-codes. Only 382 of 517 (74%) injured patients were assigned E-codes in VHA records. Sensitivity of VHA E-codes varied significantly by site (range: 59%-91%, p < 0.001). Sensitivity was highest for combat-related injuries (81%) and lowest for fall-related injuries (60%). Overall specificity of E-codes was high (92%). E-coding accuracy was markedly higher when we restricted analyses to records that had been assigned VHA E-codes. E-codes may not be valid for ascertaining source-of-injury data for all injuries among VHA rehabilitation inpatients at this time. Enhanced training and policies may ensure more widespread, standardized use and accuracy of E-codes for injured veterans treated in the VHA.
2015-01-01
Research outlets are increasingly adopting open data policies as a requisite for publication, including studies with human subjects data. We investigated whether open data policies influence participants’ rate of consent by randomly assigning participants to view consent forms with and without discussion of open data policies. No participants declined to participate, regardless of condition, nor did rates of drop-out vs. completion vary between conditions. Furthermore, no significant change in potential consent rates was reported when participants were openly asked about the influence of open data policies on their likelihood of consent. However, follow-up analyses indicated possible poor attention to consent forms, consistent with previous research. Moreover, thematic analysis of participants’ considerations of open data policy indicated multiple considerations such as concerns regarding confidentiality, anonymity, data security, and study sensitivity. The impact of open data policies on participation raises complex issues at the intersection of ethics and scientific innovation. We conclude by encouraging researchers to consider participants as stakeholders in open data policy and by providing recommendations for open data policies in human subjects research. PMID:25993308
Cummings, Jorden A; Zagrodney, Jessica M; Day, T Eugene
2015-01-01
Research outlets are increasingly adopting open data policies as a requisite for publication, including studies with human subjects data. We investigated whether open data policies influence participants' rate of consent by randomly assigning participants to view consent forms with and without discussion of open data policies. No participants declined to participate, regardless of condition, nor did rates of drop-out vs. completion vary between conditions. Furthermore, no significant change in potential consent rates was reported when participants were openly asked about the influence of open data policies on their likelihood of consent. However, follow-up analyses indicated possible poor attention to consent forms, consistent with previous research. Moreover, thematic analysis of participants' considerations of open data policy indicated multiple considerations such as concerns regarding confidentiality, anonymity, data security, and study sensitivity. The impact of open data policies on participation raises complex issues at the intersection of ethics and scientific innovation. We conclude by encouraging researchers to consider participants as stakeholders in open data policy and by providing recommendations for open data policies in human subjects research.
45 CFR 614.4 - Opening of transcript or recording.
Code of Federal Regulations, 2013 CFR
2013-10-01
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Code of Federal Regulations, 2010 CFR
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Code of Federal Regulations, 2014 CFR
2014-10-01
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Code of Federal Regulations, 2010 CFR
2010-07-01
... operation of the apprenticeship program, including but not limited to job assignment, promotion, demotion... achievement of full and equal opportunity in apprenticeship, including all data and analyses made pursuant to...
15 CFR 908.7 - Supplemental reports.
Code of Federal Regulations, 2011 CFR
2011-01-01
... RECORDS AND SUBMITTING REPORTS ON WEATHER MODIFICATION ACTIVITIES § 908.7 Supplemental reports... number, if assigned, must be made to the Administrator immediately if any report of weather modification...
Reliability of routinely collected hospital data for child maltreatment surveillance.
McKenzie, Kirsten; Scott, Debbie A; Waller, Garry S; Campbell, Margaret
2011-01-05
Internationally, research on child maltreatment-related injuries has been hampered by a lack of available routinely collected health data to identify cases, examine causes, identify risk factors and explore health outcomes. Routinely collected hospital separation data coded using the International Classification of Diseases and Related Health Problems (ICD) system provide an internationally standardised data source for classifying and aggregating diseases, injuries, causes of injuries and related health conditions for statistical purposes. However, there has been limited research to examine the reliability of these data for child maltreatment surveillance purposes. This study examined the reliability of coding of child maltreatment in Queensland, Australia. A retrospective medical record review and recoding methodology was used to assess the reliability of coding of child maltreatment. A stratified sample of hospitals across Queensland was selected for this study, and a stratified random sample of cases was selected from within those hospitals. In 3.6% of cases the coders disagreed on whether any maltreatment code could be assigned (definite or possible) versus no maltreatment being assigned (unintentional injury), giving a sensitivity of 0.982 and specificity of 0.948. The review of these cases where discrepancies existed revealed that all cases had some indications of risk documented in the records. 15.5% of cases originally assigned a definite or possible maltreatment code, were recoded to a more or less definite strata. In terms of the number and type of maltreatment codes assigned, the auditor assigned a greater number of maltreatment types based on the medical documentation than the original coder assigned (22% of the auditor coded cases had more than one maltreatment type assigned compared to only 6% of the original coded data). The maltreatment types which were the most 'under-coded' by the original coder were psychological abuse and neglect. Cases coded with a sexual abuse code showed the highest level of reliability. Given the increasing international attention being given to improving the uniformity of reporting of child-maltreatment related injuries and the emphasis on the better utilisation of routinely collected health data, this study provides an estimate of the reliability of maltreatment-specific ICD-10-AM codes assigned in an inpatient setting.
Reliability of Routinely Collected Hospital Data for Child Maltreatment Surveillance
2011-01-01
Background Internationally, research on child maltreatment-related injuries has been hampered by a lack of available routinely collected health data to identify cases, examine causes, identify risk factors and explore health outcomes. Routinely collected hospital separation data coded using the International Classification of Diseases and Related Health Problems (ICD) system provide an internationally standardised data source for classifying and aggregating diseases, injuries, causes of injuries and related health conditions for statistical purposes. However, there has been limited research to examine the reliability of these data for child maltreatment surveillance purposes. This study examined the reliability of coding of child maltreatment in Queensland, Australia. Methods A retrospective medical record review and recoding methodology was used to assess the reliability of coding of child maltreatment. A stratified sample of hospitals across Queensland was selected for this study, and a stratified random sample of cases was selected from within those hospitals. Results In 3.6% of cases the coders disagreed on whether any maltreatment code could be assigned (definite or possible) versus no maltreatment being assigned (unintentional injury), giving a sensitivity of 0.982 and specificity of 0.948. The review of these cases where discrepancies existed revealed that all cases had some indications of risk documented in the records. 15.5% of cases originally assigned a definite or possible maltreatment code, were recoded to a more or less definite strata. In terms of the number and type of maltreatment codes assigned, the auditor assigned a greater number of maltreatment types based on the medical documentation than the original coder assigned (22% of the auditor coded cases had more than one maltreatment type assigned compared to only 6% of the original coded data). The maltreatment types which were the most 'under-coded' by the original coder were psychological abuse and neglect. Cases coded with a sexual abuse code showed the highest level of reliability. Conclusion Given the increasing international attention being given to improving the uniformity of reporting of child-maltreatment related injuries and the emphasis on the better utilisation of routinely collected health data, this study provides an estimate of the reliability of maltreatment-specific ICD-10-AM codes assigned in an inpatient setting. PMID:21208411
Kasthurirathne, Suranga N; Mamlin, Burke W; Cullen, Theresa
2017-02-01
Despite significant awareness on the value of leveraging patient relationships across the healthcare continuum, there is no research on the potential of using Electronic Health Record (EHR) systems to store structured patient relationship data, or its impact on enabling better healthcare. We sought to identify which EHR systems supported effective patient relationship data collection, and for systems that do, what types of relationship data is collected, how this data is used, and the perceived value of doing so. We performed a literature search to identify EHR systems that supported patient relationship data collection. Based on our results, we defined attributes of an effective patient relationship model. The Open Medical Record System (OpenMRS), an open source medical record platform for underserved settings met our eligibility criteria for effective patient relationship collection. We performed a survey to understand how the OpenMRS patient relationship model was used, and how it brought value to implementers. The OpenMRS patient relationship model has won widespread adoption across many implementations and is perceived to be valuable in enabling better health care delivery. Patient relationship information is widely used for community health programs and enabling chronic care. Additionally, many OpenMRS implementers were using this feature to collect custom relationship types for implementation specific needs. We believe that flexible patient relationship data collection is critical for better healthcare, and can inform community care and chronic care initiatives across the world. Additionally, patient relationship data could also be leveraged for many other initiatives such as patient centric care and in the field of precision medicine.
NASA Astrophysics Data System (ADS)
Hillaire-Marcel, C.; Poirier, A.
2013-12-01
The transition from the Eocene Arctic Lake to the Arctic Ocean through the opening of Fram Strait, initially dated at ca. 18 Ma based on palynological inferences (Moran et al., 2004, Nature 441, 601-605), has been recently assigned to the very late Eocene (~ 36 Ma) based on Os-isotope stratigraphy and Re-Os isochron ages of sediments from the IODP-ACEX core (Lomonosov Ridge) (Poirier & Hillaire-Marcel, 2011, GRL 38, L14607). Here, we examine the potential linkages of this event with the Popigai meteoritic impact from northeastern Siberia, which has been dated independently at 35.7×0.2 Ma (Bottomley et al. 1997, Nature 338, 365-368). Noteworthy is the fact that in the earliest marine sediments of the ACEX core, the Os-isotope stratigraphy records an isotopic excursion which we tentatively assigned to the chondritic impactor of Popigai. Sr and Pb isotope signatures of detrital sediments (i.e., following the removal of exchangeable fractions) were thus used to further document the sources of terrigenous sediments deposited before, during, and after the transition episode. Above and below the lacustrine/marine boundary, we note relatively constant source provenances (or mixture of sources), implying that relative contributions from regional detrital sedimentary sources, thus relative erosion rates over surrounding continents, did not change much at a Ma-long time scale. On the other hand, a sharp change highlights the lacustrine/marine transition, with an abrupt shift to low values in 87Sr/88Sr, also marked by a (smaller) excursion in all three 204Pb-normalised lead isotopes values (corrected for in-situ decay of U). This isotopic excursion might also be due to the Popigai chondritic Impactor. The impact-related ejection over basaltic target materials would have produced the particulate matter of suitable composition (Wooden et al. 1993, GCA 57, 3677-3704) to account for the isotopic excursion observed. A first order estimate of the Popigai impact yields a value of ~ 10^8 megatons, resulting in a potential seismic event in the Fram Strait area with a magnitude > 10, likely to have resulted in major faulting in the area, thus possibly leading to the opening of the Strait. This very late Eocene opening of Fram Strait, would suggest a potential role of the Arctic basin in the inception of the Atlantic Meridional Overturning Circulation. With this new chronology, the entry of the Earth in the "cold house" system of the Early Oligocene, and the early indices for ice-rafting, might have being nearly synchronous in the Arctic and the circum-Antarctica.
Farber-Eger, Eric; Goodloe, Robert; Boston, Jonathan; Bush, William S.; Crawford, Dana C.
2017-01-01
We describe here the extraction of country-of-origin, an acculturation variable relevant for gene-environment studies, in a biorepository linked to de-identified electronic health records (EHRs) assessed by the Epidemiologic Architecture for Genes Linked to Environment (EAGLE), a study site of the Population Architecture using Genomics and Epidemiology (PAGE) I study. We extracted country-of-origin from the unstructured clinical free text using regular expressions within the MySQL relational database system in a cohort of 15,863 subjects of mostly non-European descent (including 11,519 African Americans, 1,702 Hispanics, and 1,118 Asians). We performed searches for 231 world countries (including independent sovereign states, dependent areas, and disputed territories) and common misspellings in >14 gigabytes of data including >13 billion characters of clinical text. Manual review of a fraction of the initial country-of-origin assignments established rules for data cleaning and quality control to achieve final country-of-origin status for each subject. After data cleaning, a total of 1,911/15,893 (12.02%) subjects were assigned to a country-of-origin outside of the United States. Mexico was the most commonly assigned country outside of the United States (264 subjects; 13.8% of subjects with a foreign country-of-origin assignment). The distribution of the countries assigned followed expectations based on known migration patterns to the United States with an emphasis on the southeastern region. These data suggest country-of-origin can be successfully extracted from unstructured clinical text for downstream genetic association studies. PMID:28815105
Farber-Eger, Eric; Goodloe, Robert; Boston, Jonathan; Bush, William S; Crawford, Dana C
2017-01-01
We describe here the extraction of country-of-origin, an acculturation variable relevant for gene-environment studies, in a biorepository linked to de-identified electronic health records (EHRs) assessed by the Epidemiologic Architecture for Genes Linked to Environment (EAGLE), a study site of the Population Architecture using Genomics and Epidemiology (PAGE) I study. We extracted country-of-origin from the unstructured clinical free text using regular expressions within the MySQL relational database system in a cohort of 15,863 subjects of mostly non-European descent (including 11,519 African Americans, 1,702 Hispanics, and 1,118 Asians). We performed searches for 231 world countries (including independent sovereign states, dependent areas, and disputed territories) and common misspellings in >14 gigabytes of data including >13 billion characters of clinical text. Manual review of a fraction of the initial country-of-origin assignments established rules for data cleaning and quality control to achieve final country-of-origin status for each subject. After data cleaning, a total of 1,911/15,893 (12.02%) subjects were assigned to a country-of-origin outside of the United States. Mexico was the most commonly assigned country outside of the United States (264 subjects; 13.8% of subjects with a foreign country-of-origin assignment). The distribution of the countries assigned followed expectations based on known migration patterns to the United States with an emphasis on the southeastern region. These data suggest country-of-origin can be successfully extracted from unstructured clinical text for downstream genetic association studies.
Gorczyca, Agnes; Moizan, Virginie; Chizallet, Celine; Proux, Olivier; Del Net, William; Lahera, Eric; Hazemann, Jean-Louis; Raybaud, Pascal; Joly, Yves
2014-11-10
Platinum nanoclusters highly dispersed on γ-alumina are widely used as heterogeneous catalysts. To understand the chemical interplay between the Pt nanoparticles, the support, and the reductive atmosphere, we performed X-ray absorption near edge structure (XANES) in situ experiments recorded in high energy resolution fluorescence detection (HERFD) mode. Spectra are assigned by comparison with simulated XANES spectra on models obtained by molecular dynamics (DFT-MD). We propose platinum cluster morphologies and quantify the hydrogen coverages compatible with XANES spectra recorded at variable hydrogen pressures and temperatures. Using cutting-edge methodologies to assign XANES spectra, this work gives unequalled atomic insights into the characterization of supported nanoclusters. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
NASA Astrophysics Data System (ADS)
Black, Christopher; Voigts, Jakob; Agrawal, Uday; Ladow, Max; Santoyo, Juan; Moore, Christopher; Jones, Stephanie
2017-06-01
Objective. Electroencephalography (EEG) offers a unique opportunity to study human neural activity non-invasively with millisecond resolution using minimal equipment in or outside of a lab setting. EEG can be combined with a number of techniques for closed-loop experiments, where external devices are driven by specific neural signals. However, reliable, commercially available EEG systems are expensive, often making them impractical for individual use and research development. Moreover, by design, a majority of these systems cannot be easily altered to the specification needed by the end user. We focused on mitigating these issues by implementing open-source tools to develop a new EEG platform to drive down research costs and promote collaboration and innovation. Approach. Here, we present methods to expand the open-source electrophysiology system, Open Ephys (www.openephys.org), to include human EEG recordings. We describe the equipment and protocol necessary to interface various EEG caps with the Open Ephys acquisition board, and detail methods for processing data. We present applications of Open Ephys + EEG as a research tool and discuss how this innovative EEG technology lays a framework for improved closed-loop paradigms and novel brain-computer interface experiments. Main results. The Open Ephys + EEG system can record reliable human EEG data, as well as human EMG data. A side-by-side comparison of eyes closed 8-14 Hz activity between the Open Ephys + EEG system and the Brainvision ActiCHamp EEG system showed similar average power and signal to noise. Significance. Open Ephys + EEG enables users to acquire high-quality human EEG data comparable to that of commercially available systems, while maintaining the price point and extensibility inherent to open-source systems.
Black, Christopher; Voigts, Jakob; Agrawal, Uday; Ladow, Max; Santoyo, Juan; Moore, Christopher; Jones, Stephanie
2017-06-01
Electroencephalography (EEG) offers a unique opportunity to study human neural activity non-invasively with millisecond resolution using minimal equipment in or outside of a lab setting. EEG can be combined with a number of techniques for closed-loop experiments, where external devices are driven by specific neural signals. However, reliable, commercially available EEG systems are expensive, often making them impractical for individual use and research development. Moreover, by design, a majority of these systems cannot be easily altered to the specification needed by the end user. We focused on mitigating these issues by implementing open-source tools to develop a new EEG platform to drive down research costs and promote collaboration and innovation. Here, we present methods to expand the open-source electrophysiology system, Open Ephys (www.openephys.org), to include human EEG recordings. We describe the equipment and protocol necessary to interface various EEG caps with the Open Ephys acquisition board, and detail methods for processing data. We present applications of Open Ephys + EEG as a research tool and discuss how this innovative EEG technology lays a framework for improved closed-loop paradigms and novel brain-computer interface experiments. The Open Ephys + EEG system can record reliable human EEG data, as well as human EMG data. A side-by-side comparison of eyes closed 8-14 Hz activity between the Open Ephys + EEG system and the Brainvision ActiCHamp EEG system showed similar average power and signal to noise. Open Ephys + EEG enables users to acquire high-quality human EEG data comparable to that of commercially available systems, while maintaining the price point and extensibility inherent to open-source systems.
Absorption spectra of ammonia near 1 μm
NASA Astrophysics Data System (ADS)
Barton, Emma J.; Polyansky, Oleg L.; Yurchenko, Sergei. N.; Tennyson, Jonathan; Civiš, S.; Ferus, M.; Hargreaves, R.; Ovsyannikov, R. I.; Kyuberis, A. A.; Zobov, N. F.; Béguier, S.; Campargue, A.
2017-12-01
An ammonia absorption spectrum recorded at room temperature in the region 8800-10,400 cm-1 is analysed using a variational line list, BYTe, and ground state energies determined using the MARVEL procedure. BYTe is used as a starting point to initialise assignments by combination differences and the method of branches. Assignments are presented for the region 9400-9850 cm-1. 642 lines are assigned to 6 previously unobserved vibrational bands, (2v1 + 2 v42) ±, (2v1 + v31) ± and (v1 + v31 + 2 v42) ±, leading to 428 new energy levels with 208 confirmed by combination differences. A recently calculated purely ab initio NH3 PES is also used to calculate rovibrational energy levels. Comparison with assigned levels shows better agreement between observed and calculated levels than for BYTe for higher vibrational bands.
Neige, Pascal; Lapierre, Hervé; Merle, Didier
2016-01-01
New coleoid cephalopods are described from statolith remains from the Middle Eocene (Middle Lutetian) of the Paris Basin. Fifteen fossil statoliths are identified and assigned to the Sepiidae (Sepia boletzkyi sp. nov.,? Sepia pira sp. nov.), Loliginidae (Loligo clarkei sp. nov.), and Ommastrephidae (genus indet.) families. The sediments containing these fossils indicate permanent aquatic settings in the infralittoral domain. These sediments range in age from 46 Mya to 43 Mya. Analysis of the fossil record of statoliths (from findings described here, together with a review of previously published data) indicates marked biases in our knowledge. Fossil statoliths are known from as far back as the Early Jurassic (199.3 to 190.8 Mya) but surprisingly, to the best of our knowledge, no record occurs in the Cretaceous. This is a “knowledge bias” and clearly calls for further studies. Finally, we attempt to compare findings described here with fossils previously used to constrain divergence and/or diversification ages of some coleoid subclades in molecular phylogenies. This comparison clearly indicates that the new records detailed here will challenge some estimated divergence times of coleoid cephalopod subclades. PMID:27192490
Neige, Pascal; Lapierre, Hervé; Merle, Didier
2016-01-01
New coleoid cephalopods are described from statolith remains from the Middle Eocene (Middle Lutetian) of the Paris Basin. Fifteen fossil statoliths are identified and assigned to the Sepiidae (Sepia boletzkyi sp. nov.,? Sepia pira sp. nov.), Loliginidae (Loligo clarkei sp. nov.), and Ommastrephidae (genus indet.) families. The sediments containing these fossils indicate permanent aquatic settings in the infralittoral domain. These sediments range in age from 46 Mya to 43 Mya. Analysis of the fossil record of statoliths (from findings described here, together with a review of previously published data) indicates marked biases in our knowledge. Fossil statoliths are known from as far back as the Early Jurassic (199.3 to 190.8 Mya) but surprisingly, to the best of our knowledge, no record occurs in the Cretaceous. This is a "knowledge bias" and clearly calls for further studies. Finally, we attempt to compare findings described here with fossils previously used to constrain divergence and/or diversification ages of some coleoid subclades in molecular phylogenies. This comparison clearly indicates that the new records detailed here will challenge some estimated divergence times of coleoid cephalopod subclades.
46 CFR 67.200 - Instruments eligible for filing and recording.
Code of Federal Regulations, 2010 CFR
2010-10-01
..., satisfactions, and releases thereof; (d) Preferred mortgages and assignments, assumptions, supplements, amendments, subordinations, satisfactions, and releases thereof; (e) Interlender agreements affecting..., amendments, and satisfactions and releases thereof. ...
29 CFR 801.61 - Designation of record.
Code of Federal Regulations, 2010 CFR
2010-07-01
... OF THE EMPLOYEE POLYGRAPH PROTECTION ACT OF 1988 Administrative Proceedings Rules of Practice § 801..., letter, and designation assigned to each such proceeding shall be clearly displayed on each pleading...
Adoptees in Search of Their Past: Policy Induced Strain on Adoptive Families and Birth Parents.
ERIC Educational Resources Information Center
Simpson, Mark; And Others
1981-01-01
Explores the impact of Minnesota's Open Birth Record Law. Studied adoptees in search of information and contact with their birth parents. Caseworkers were relatively successful in the searches, but personal contacts were achieved for only 35 percent of the adoptees. Supports the value of the Open Birth Record law. (Author)
77 FR 21808 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-11
... and open source records and commercial database. EXEMPTIONS CLAIMED FOR THE SYSTEM: The Attorney... notification procedures, the record access procedures, the contesting record procedures, the record source..., confidential sources, and victims of crimes. The offenses and alleged offenses associated with the individuals...
Rabi, A; Maheshwari, Rahul; Srinivasan, Bhuvaneshwari; Warad, Lata P; Suvarna, C C; Tank, Kartik S
2018-01-01
The present study was conducted with the aim of evaluating the effectiveness of antimicrobial therapy following extraction of an impacted mandibular third molar. This randomized controlled trial was conducted on a total of 60 patients who were randomly assigned into three groups: Group I individuals were given 625 mg of combined amoxicillin and clavulanic acid tablet; 625 mg of combined amoxicillin and clavulanic acid tablet + 400 mg metronidazole tablet was given to group II individuals; whereas group III individuals were assigned no treatment. All the individuals underwent surgical extraction of impacted mandibular third molars under strict aseptic techniques, with minimal trauma to the surrounding tissues. Mouth opening in millimeters was recorded postoperatively using Vernier calipers on the 1st, 3rd, 5th, and 7th days. A 4-point visual analog scale (VAS) was used for assessing postoperative pain. Patient satisfaction was further assessed in a subjective manner using a graded scale from "very satisfied" to "very unsatisfied". The present study included individuals between the ages of 20 and 35 years. Group II individuals showed slightly better satisfaction than the other group individuals. There was no statistically significant difference between the mean age of groups. It was observed that on day 3, the number of individuals with severe pain was slightly reduced in the group I compared with group III individuals. On day 5, participants with no pain were significantly more in group II followed by group I. Furthermore, there was a statistically significant difference between the study groups with respect to mouth opening on days 3 and 5. It was concluded from this trial that the administration of postoperative antimicrobials showed no significant differences in the degree of postoperative complications that occur following the surgical extraction of impacted mandibular third molars. Antimicrobial drugs are routinely used to reduce the chances of surgical site infection, either preopera-tively or postoperatively. Therefore, the clinicians should have sound knowledge about choosing the better antimicrobial drug after the extraction of impacted third molars.
NASA Astrophysics Data System (ADS)
Zuo, Fanfan; Heimhofer, Ulrich; Huck, Stefan; Erbacher, Jochen; Bodin, Stephane
2017-04-01
Stratigraphic uncertainties due to the lack of open marine marker fossils (e.g. ammonites) hamper the precise age assignment and stratigraphic correlation of Kimmeridgian strata found in the Lower Saxony Basin of Northern Germany. Correlation of these deposits with the Jurassic standard ammonite zonation is still difficult, since the existing ostracod biostratigraphy is facies-controlled and of only limited stratigraphic precision. In this study, a chemostratigraphic approach has been chosen and biogenic shell material produced by brachiopods, oysters and lithiotids is evaluated for its reliability to act as proxy of the original Jurassic seawater strontium isotope composition. Low-Mg calcite shells have been collected from three stratigraphic sections accessible in open-cast quarries located in the Lower Saxony Basin of Northern Germany. In order to identify diagenetically altered shell calcite, trace element and stable isotope analysis of 227 calcite samples (oysters=101; brachiopods=60; Trichites=52) has been carried out. The geochemical results reveal that (1) concentration of different trace elements varies between the different groups of shell-forming organisms, which may be related to vital effects and (2) high strontium contents, low Mn and Fe contents and the lack of correlation between these elements indicate near-pristine calcite shells, and therefore shells are supposed to record the ambient sea water composition during the Late Jurassic. Strontium-isotope (87Sr/86Sr) analysis of diagenetically screened samples indicates an Early Kimmeridgian age of the studied deposits, which is in accordance with ostracod biostratigraphic data. An increasing trend in 87Sr/86Sr with stratigraphic height fits well with the global strontium-isotope curve. Besides, similar 87Sr/86Sr ratios derived from different organisms from a single stratigraphic level highlight the suitability of the shells for strontium-isotope stratigraphy. Despite the shallow-marine character of the studied deposits, no evidence for significant riverine influence on the strontium-isotope signature is observed. The new chemostratigraphic data will provide a more precise age assignment for Kimmeridgian strata in the Lower Saxony Basin and thus enable the establishment of a solid integrated stratigraphic scheme that can be used for correlation on both regional and global scale.
Roig-Casasús, Sergio; María Blasco, José; López-Bueno, Laura; Blasco-Igual, María Clara
2017-03-01
Sensorimotor training has proven to be an efficient approach for recovering balance control following total knee replacement (TKR). The purpose of this trial was to evaluate the influence of specific balance-targeted training using a dynamometric platform on the overall state of balance in older adults undergoing TKR. This was a randomized controlled clinical trial conducted at a university hospital rehabilitation unit. Patients meeting the inclusion criteria were randomly assigned to a control group or an experimental group. Both groups participated in the same 4-week postoperative rehabilitation training protocol. Participants in the experimental group performed additional balance training with a dynamometric platform consisting of tests related to stability challenges, weight-shifting, and moving to the limits of stability. The primary outcome measure was the overall state of balance rated according to the Berg Balance Scale. Secondary outcomes in terms of balance were the Timed Up and Go Test, Functional Reach Test, and Romberg open and closed-eyes tests. Data processing included between-group analysis of covariance, minimal detectable change assessment for the primary outcome measure, and effect size estimation. Confidence intervals (CIs) were set at 95%. Forty-three participants meeting the inclusion criteria and having signed the informed consent were randomly assigned to 2 groups. Thirty-seven completed the training (86.1%). Significant between-group differences in balance performance were found as measured with the Berg Balance Scale (P = .03) and Functional Reach Test (P = .04) with a CI = 95%. Significant differences were not recorded for the Timed Up and Go Test or Romberg open and closed-eyes tests (P > .05). Furthermore, Cohen's effect size resulted in a value of d = 0.97, suggesting a high practical significance of the trial. According to the Berg Balance Scale and Functional Reach Test, participants with TKR who have followed a 4-week training program using a dynamometric platform improved balance performance to a higher extent than a control group training without such a device. The inclusion of this instrument in the functional training protocol may be beneficial for recovering balance following TKR.
National Institute of Standards and Technology Data Gateway
SRD 115 Hydrocarbon Spectral Database (Web, free access) All of the rotational spectral lines observed and reported in the open literature for 91 hydrocarbon molecules have been tabulated. The isotopic molecular species, assigned quantum numbers, observed frequency, estimated measurement uncertainty and reference are given for each transition reported.
National Institute of Standards and Technology Data Gateway
SRD 114 Diatomic Spectral Database (Web, free access) All of the rotational spectral lines observed and reported in the open literature for 121 diatomic molecules have been tabulated. The isotopic molecular species, assigned quantum numbers, observed frequency, estimated measurement uncertainty, and reference are given for each transition reported.
National Institute of Standards and Technology Data Gateway
SRD 117 Triatomic Spectral Database (Web, free access) All of the rotational spectral lines observed and reported in the open literature for 55 triatomic molecules have been tabulated. The isotopic molecular species, assigned quantum numbers, observed frequency, estimated measurement uncertainty and reference are given for each transition reported.
Smith, Iain M; Naumann, David N; Guyver, Paul; Bishop, Jonathan; Davies, Simon; Lundy, Jonathan B; Bowley, Douglas M
2015-01-01
Anatomic measures of injury burden provide key information for studies of prehospital and in-hospital trauma care. The military version of the Abbreviated Injury Scale [AIS(M)] is used to score injuries in deployed military hospitals. Estimates of total trauma burden are derived from this. These scores are used for categorization of patients, assessment of care quality, and research studies. Scoring is normally performed retrospectively from chart review. We compared data recorded in the UK Joint Theatre Trauma Registry (JTTR) and scores calculated independently at the time of surgery by the operating surgeons to assess the concordance between surgeons and trauma nurse coordinators in assigning injury severity scores. Trauma casualties treated at a deployed Role 3 hospital were assigned AIS(M) scores by surgeons between 24 September 2012 and 16 October 2012. JTTR records from the same period were retrieved. The AIS(M), Injury Severity Score (ISS), and New Injury Severity Score (NISS) were compared between datasets. Among 32 matched casualties, 214 injuries were recorded in the JTTR, whereas surgeons noted 212. Percentage agreement for number of injuries was 19%. Surgeons scored 75 injuries as "serious" or greater compared with 68 in the JTTR. Percentage agreement for the maximum AIS(M), ISS, and NISS assigned to cases was 66%, 34%, and 28%, respectively, although the distributions of scores were not statistically different (median ISS: surgeons: 20 [interquartile range (IQR), 9-28] versus JTTR: 17.5 [IQR, 9-31.5], p = .7; median NISS: surgeons: 27 [IQR, 12-42] versus JTTR: 25.5 [IQR, 11.5-41], p = .7). There are discrepancies in the recording of AIS(M) between surgeons directly involved in the care of trauma casualties and trauma nurse coordinators working by retrospective chart review. Increased accuracy might be achieved by actively collaborating in this process. 2015.
Raman-Spektren der Hexathiohypodiphosphate des NH4, Mg, Ca, Sr und Ba
NASA Astrophysics Data System (ADS)
Pätzmann, Ulrich; Brockner, Wolfgang
1987-06-01
The title compounds have been prepared and their Raman spectra recorded. The observed frequencies of (NH4)4P2S6 and Mg2P2S6 are assigned on the basis of P2S64- units with D3d symmetry. The Raman spectra of the Calcium, Strontium and Barium compounds indicate symmetry splitting, therefore the P2S64- frequencies are assigned with C2h symmetry. This assignment is supported by the correlation D3d → C2h. It is concluded that Sr2P2S6 and Ba2P2S6 crystallize in the monoclinic modification II.
Effects of nanotechnologies-based devices on postural control in healthy subjects.
Malchiodi Albedi, Giovanna; Corna, Stefano; Aspesi, Valentina; Clerici, Daniela; Parisio, Cinzia; Seitanidis, Jonathan; Cau, Nicola; Brugliera, Luigia; Capodaglio, Paolo
2017-09-05
The aim of the present preliminary randomized controlled study was to ascertain whether the use of newly developed nanotechnologies-based patches can influence posture control of healthy subjects. Thirty healthy female subjects (age 39.4 years, BMI 22.74 kg/m2) were randomly assigned to two groups: one with active patches and a control group with sham patches. Two patches were applied with a tape: one on the subject's sternum and the other on the C7 apophysis. Body sway during quiet upright stance was recorded with a dynamometric platform. Each subject was tested under two visual conditions, eyes open and closed. We used a blocked stratified randomization procedure conducted by a third party. Subjects wearing the sham patches showed a significant increase of the centre of pressure sway area after 4 hours when they performed the habitual moderate-intensity work activities. In the active patch group, a decrease of the sway path was evident, providing evidence of an enhanced balance control. Our preliminary findings on healthy subjects indicate that nanotechnological devices generating ultra-low electromagnetic fields can improve posture control.
NMReDATA, a standard to report the NMR assignment and parameters of organic compounds.
Pupier, Marion; Nuzillard, Jean-Marc; Wist, Julien; Schlörer, Nils E; Kuhn, Stefan; Erdelyi, Mate; Steinbeck, Christoph; Williams, Antony J; Butts, Craig; Claridge, Tim D W; Mikhova, Bozhana; Robien, Wolfgang; Dashti, Hesam; Eghbalnia, Hamid R; Farès, Christophe; Adam, Christian; Kessler, Pavel; Moriaud, Fabrice; Elyashberg, Mikhail; Argyropoulos, Dimitris; Pérez, Manuel; Giraudeau, Patrick; Gil, Roberto R; Trevorrow, Paul; Jeannerat, Damien
2018-04-14
Even though NMR has found countless applications in the field of small molecule characterization, there is no standard file format available for the NMR data relevant to structure characterization of small molecules. A new format is therefore introduced to associate the NMR parameters extracted from 1D and 2D spectra of organic compounds to the proposed chemical structure. These NMR parameters, which we shall call NMReDATA (for nuclear magnetic resonance extracted data), include chemical shift values, signal integrals, intensities, multiplicities, scalar coupling constants, lists of 2D correlations, relaxation times, and diffusion rates. The file format is an extension of the existing Structure Data Format, which is compatible with the commonly used MOL format. The association of an NMReDATA file with the raw and spectral data from which it originates constitutes an NMR record. This format is easily readable by humans and computers and provides a simple and efficient way for disseminating results of structural chemistry investigations, allowing automatic verification of published results, and for assisting the constitution of highly needed open-source structural databases. Copyright © 2018 John Wiley & Sons, Ltd.
Provider-patient adherence dialogue in HIV care: results of a multisite study.
Laws, M Barton; Beach, Mary Catherine; Lee, Yoojin; Rogers, William H; Saha, Somnath; Korthuis, P Todd; Sharp, Victoria; Wilson, Ira B
2013-01-01
Few studies have analyzed physician-patient adherence dialogue about ARV treatment in detail. We comprehensively describe physician-patient visits in HIV care, focusing on ARV-related dialogue, using a system that assigns each utterance both a topic code and a speech act code. Observational study using audio recordings of routine outpatient visits by people with HIV at specialty clinics. Providers were 34 physicians and 11 non-M.D. practitioners. Of 415 patients, 66% were male, 59% African-American. 78% reported currently taking ARVs. About 10% of utterances concerned ARV treatment. Among those using ARVs, 15% had any adherence problem solving dialogue. ARV problem solving talk included significantly more directives and control parameter utterances by providers than other topics. Providers were verbally dominant, asked five times as many questions as patients, and made 21 times as many directive utterances. Providers asked few open questions, and rarely checked patients' understanding. Physicians respond to the challenges of caring for patients with HIV by adopting a somewhat physician-centered approach which is particularly evident in discussions about ARV adherence.
Dyrlund, Thomas F; Poulsen, Ebbe T; Scavenius, Carsten; Sanggaard, Kristian W; Enghild, Jan J
2012-09-01
Data processing and analysis of proteomics data are challenging and time consuming. In this paper, we present MS Data Miner (MDM) (http://sourceforge.net/p/msdataminer), a freely available web-based software solution aimed at minimizing the time required for the analysis, validation, data comparison, and presentation of data files generated in MS software, including Mascot (Matrix Science), Mascot Distiller (Matrix Science), and ProteinPilot (AB Sciex). The program was developed to significantly decrease the time required to process large proteomic data sets for publication. This open sourced system includes a spectra validation system and an automatic screenshot generation tool for Mascot-assigned spectra. In addition, a Gene Ontology term analysis function and a tool for generating comparative Excel data reports are included. We illustrate the benefits of MDM during a proteomics study comprised of more than 200 LC-MS/MS analyses recorded on an AB Sciex TripleTOF 5600, identifying more than 3000 unique proteins and 3.5 million peptides. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
A Record Book of Open Heart Surgical Cases between 1959 and 1982, Hand-Written by a Cardiac Surgeon.
Kim, Won-Gon
2016-08-01
A book of brief records of open heart surgery underwent between 1959 and 1982 at Seoul National University Hospital was recently found. The book was hand-written by the late professor and cardiac surgeon Yung Kyoon Lee (1921-1994). This book contains valuable information about cardiac patients and surgery at the early stages of the establishment of open heart surgery in Korea, and at Seoul National University Hospital. This report is intended to analyze the content of the book.
Patient Expectancy as a Mediator of Placebo Effects in Antidepressant Clinical Trials.
Rutherford, Bret R; Wall, Melanie M; Brown, Patrick J; Choo, Tse-Hwei; Wager, Tor D; Peterson, Bradley S; Chung, Sarah; Kirsch, Irving; Roose, Steven P
2017-02-01
Causes of placebo effects in antidepressant trials have been inferred from observational studies and meta-analyses, but their mechanisms have not been directly established. The goal of this study was to examine in a prospective, randomized controlled trial whether patient expectancy mediates placebo effects in antidepressant studies. Adult outpatients with major depressive disorder were randomly assigned to open or placebo-controlled citalopram treatment. Following measurement of pre- and postrandomization expectancy, participants were treated with citalopram or placebo for 8 weeks. Independent samples t tests determined whether patient expectancy differed between the open and placebo-controlled groups, and mixed-effects models assessed group effects on Hamilton Depression Rating Scale (HAM-D) scores over time while controlling for treatment assignment. Finally, mediation analyses tested whether between-group differences in patient expectancy mediated the group effect on HAM-D scores. Postrandomization expectancy scores were significantly higher in the open group (mean=12.1 [SD=2.1]) compared with the placebo-controlled group (mean=11.0 [SD=2.0]). Mixed-effects modeling revealed a significant week-by-group interaction, indicating that HAM-D scores for citalopram-treated participants declined at a faster rate in the open group compared with the placebo-controlled group. Patient expectations postrandomization partially mediated group effects on week 8 HAM-D. Patient expectancy is a significant mediator of placebo effects in antidepressant trials. Expectancy-related interventions should be investigated as a means of controlling placebo responses in antidepressant clinical trials and improving patient outcome in clinical treatment.
Santosh Kumar, B B; Aruna, D R; Gowda, Vinayak S; Galagali, Sushama R; Prashanthy, R; Navaneetha, H
2013-09-01
Recently, there has been interest in non-mammalian collagen sources such as fish collagen in periodontal regeneration. In the present study, collagen barrier membrane of fish origin was assessed in the treatment of periodontal intrabony defects. Ten systemically healthy chronic periodontitis patients having a paired osseous defect in the mandibular posterior teeth were selected and randomly assigned to receive a collagen membrane (test) or open flap debridement (control) in a split mouth design. Clinical parameters such as Plaque index, Gingival bleeding index, Probing pocket depth, Relative attachment level, and Recession were recorded at baseline, 3, 6, and at 9 months, while radiographic evaluation was done to assess alveolar crestal bone level and percentage of defect fill at 6 and 9 months using autoCAD 2007 software. Student's t test (two-tailed, dependent) was used to find the significance of study parameters on continuous scale. Significance was set at 5% level of significance. Wilcoxon signed rank test was used to find the significance of percentage change of defect fill. The comparison between the two groups did not show any statistically significant differences in the parameters assessed (P > 0.05) but, within each group, clinical parameters showed statistically significant differences from baseline to 9 months (P < 0.05). Within the limits of the study, it can be inferred that no significant differences were found either by using collagen membrane of fish origin or open flap debridement in the treatment of periodontal intrabony defects.
Koh, Jae-Chul; Lee, Jong Seok; Lee, Youn-Woo; Chang, Chul Ho
2010-11-01
For patients suspicious of cervical spine injury, a Philadelphia cervical collar is usually applied. Application of Philadelphia cervical collar may cause difficult airway. The aim of this study was to evaluate the laryngeal view and the success rate at first intubation attempt of the Airtraq and conventional laryngoscopy in patients with simulated cervical spine injury after application of a Philadelphia cervical collar. Anesthesia was induced with propofol, remifentanil, and rocuronium. After a Philadelphia cervical collar applied, patients were randomly assigned to tracheal intubation with an Airtraq (Group A, n = 25) or with conventional laryngoscopy (Group L, n = 25). Measurements included intubation time, success rate of first intubation attempt, number of intubation attempts, and percentage of glottic opening (POGO) score. Mean blood pressure and heart rate were also recorded at baseline, just before and after intubation. The success rate of the first attempt in Group A (96%) was significantly greater than with the Group L (40%). POGO score was significantly greater in Group A (84 ± 20%) than in Group L (6 ± 11%). The duration of successful intubation at first tracheal intubation attempt and hemodynamic changes were not significantly different between the two groups. The Airtraq offers a better laryngeal view and higher success rate at first intubation attempt in patients who are applied with a Philadelphia cervical collar due to suspicion of cervical spine injury.
Installation Restoration Program. Phase I: Records Search Minot Air Force Base, North Dakota.
1984-12-01
MAFB and Grand Forks AFB. This move localized command along with •. •• insuring that assigned units would be capable of conducting aerial...were realigned !•;>•’ to become members of the 57th AD. Also on May 1, Grand Forks AFB was \\.•/ assigned to the 4th AD at F.E. Warren AFB, Wyoming...potential for vertical - - stratification of possible ground water contaminants. During drilling, Shelby tube samples should be taken to provide soils
Open courses: one view of the future of online education.
Alemi, Farrokh; Maddox, P J
2008-01-01
Open courses provide the entire course (lectures, assignments, syllabus, student's discussions, and student's projects) online without revealing student's personal information. We report on our experience in managing 8 open online courses at http://nhs.georgetown.edu/open. Open courses have several advantages over password protected courses: (1) they are available through search engines and thus reduce the program's marketing cost, (2) continuous feedback from the web enables rapid improvements to the course, (3) customer relationship tools, tied to open courses, radically reduce faculty time spent on one-on-one emails while increasing student/faculty interaction. We provide details of one course. In 15 weeks, 803 emails were received by and 1181 sent by the faculty (all within 6% of a working week and 82% savings of faculty time). We show how open courses can be accessed through search engines, how students questions are answered on the web and how student projects, in popular sites such as You Tube and Face Book, improve course marketing. The paper reports that student satisfaction with three open online courses delivered overall several semesters was high.
Open source electronic health records and chronic disease management.
Goldwater, Jason C; Kwon, Nancy J; Nathanson, Ashley; Muckle, Alison E; Brown, Alexa; Cornejo, Kerri
2014-02-01
To study and report on the use of open source electronic health records (EHR) to assist with chronic care management within safety net medical settings, such as community health centers (CHC). The study was conducted by NORC at the University of Chicago from April to September 2010. The NORC team undertook a comprehensive environmental scan, including a literature review, a dozen key informant interviews using a semistructured protocol, and a series of site visits to CHC that currently use an open source EHR. Two of the sites chosen by NORC were actively using an open source EHR to assist in the redesign of their care delivery system to support more effective chronic disease management. This included incorporating the chronic care model into an CHC and using the EHR to help facilitate its elements, such as care teams for patients, in addition to maintaining health records on indigent populations, such as tuberculosis status on homeless patients. The ability to modify the open-source EHR to adapt to the CHC environment and leverage the ecosystem of providers and users to assist in this process provided significant advantages in chronic care management. Improvements in diabetes management, controlled hypertension and increases in tuberculosis vaccinations were assisted through the use of these open source systems. The flexibility and adaptability of open source EHR demonstrated its utility and viability in the provision of necessary and needed chronic disease care among populations served by CHC.
Effect of Making an Audio Recording of a Term Paper on Writing Quality
ERIC Educational Resources Information Center
Taxis, Tasia M.; Lannin, Amy A.; Selting, Bonita R.; Lamberson, William R.
2014-01-01
Writing-to-learn assignments engage students with a problem while they develop writing skills. It is difficult in large classes to provide training in proofreading and editing techniques. The purpose of this project was to determine if a term paper was improved after making an audio recording of a draft of the paper. Data from 2 years of papers…
21 CFR 1030.10 - Microwave ovens.
Code of Federal Regulations, 2012 CFR
2012-04-01
... after October 6, 1971. (b) Definitions—(1) Microwave oven means a device designed to heat, cook, or dry food through the application of electromagnetic energy at frequencies assigned by the Federal... prevent emission of microwave energy from the passage or opening which provides access to the cavity. (4...
21 CFR 1030.10 - Microwave ovens.
Code of Federal Regulations, 2014 CFR
2014-04-01
... after October 6, 1971. (b) Definitions—(1) Microwave oven means a device designed to heat, cook, or dry food through the application of electromagnetic energy at frequencies assigned by the Federal... prevent emission of microwave energy from the passage or opening which provides access to the cavity. (4...
21 CFR 1030.10 - Microwave ovens.
Code of Federal Regulations, 2013 CFR
2013-04-01
... after October 6, 1971. (b) Definitions—(1) Microwave oven means a device designed to heat, cook, or dry food through the application of electromagnetic energy at frequencies assigned by the Federal... prevent emission of microwave energy from the passage or opening which provides access to the cavity. (4...
ERIC Educational Resources Information Center
Minix, Dean A.
1990-01-01
Describes an open admissions program, a public university's nontraditional population, and their unique academic needs. Provides a political science briefing book assignment in which students research and write about one country. Claims the book is effective in helping students to organize and focus their thoughts and to improve their research and…
Opening Up High Technology Careers to Women.
ERIC Educational Resources Information Center
Bumstead, Richard
1981-01-01
Describes a program that aims at increasing the number of women technicians in computer and other electronics industries. Discusses how more women are entering the computer field in Massachusetts, the stigma of technical work, typical assignments, lack of short-term courses, and recent responses to needs. (CT)
Khvostenko, Olga G; Kinzyabulatov, Renat R; Khatymova, Laysan Z; Tseplin, Evgeniy E
2017-10-05
This study was undertaken to find the previously unknown lowest triplet of the isolated molecule of tetracyanoquinodimethane (TCNQ), which is a widely used organic semiconductor. The problem is topical because the triplet excitation of this compound is involved in some processes which occur in electronic devices incorporating TCNQ and its derivatives, and information on the TCNQ triplet is needed for better understanding of these processes. The lowest triplet of TCNQ was obtained at 1.96 eV using UV-vis absorption spectroscopy with Br-containing solvents. Production of the triplet band with sufficient intensity in the spectra was provided by the capacity of the Br atom to augment the triplet excitation and through using a 100 mm cuvette. The assignment of the corresponding spectral band to the triplet transition was made by observation that this band appeared only in the spectra recorded in Br-containing solvents but not in spectra recorded in other solvents. Additional support for the triplet assignment came from the overall UV-vis absorption spectra of TCNQ recorded in various solvents, using a 10 mm cuvette, in the 1.38-6.5 eV energy range. Singlet transitions of the neutral TCNQ o molecule and doublet transitions of the TCNQ ¯ negative ion were identified in these overall spectra and were assigned with TD B3LYP/6-31G calculations. Determination of the lowest triplet of TCNQ attained in this work may be useful for theoretical studies and practical applications of this important compound.
Refson, Keith; Parker, Stewart F
2015-01-01
The fullerene C70 may be considered as the shortest possible nanotube capped by a hemisphere of C60 at each end. Vibrational spectroscopy is a key tool in characterising fullerenes, and C70 has been studied several times and spectral assignments proposed. Unfortunately, many of the modes are either forbidden or have very low infrared or Raman intensity, even if allowed. Inelastic neutron scattering (INS) spectroscopy is not subject to selection rules, and all the modes are allowed. We have obtained a new INS spectrum from a large sample recorded at the highest resolution available. An advantage of INS spectroscopy is that it is straightforward to calculate the spectral intensity from a model. We demonstrate that all previous assignments are incorrect in at least some respects and propose a new assignment based on periodic density functional theory (DFT) that successfully reproduces the INS, infrared, and Raman spectra. PMID:26491642
Schober, Daniel; Jacob, Daniel; Wilson, Michael; Cruz, Joseph A; Marcu, Ana; Grant, Jason R; Moing, Annick; Deborde, Catherine; de Figueiredo, Luis F; Haug, Kenneth; Rocca-Serra, Philippe; Easton, John; Ebbels, Timothy M D; Hao, Jie; Ludwig, Christian; Günther, Ulrich L; Rosato, Antonio; Klein, Matthias S; Lewis, Ian A; Luchinat, Claudio; Jones, Andrew R; Grauslys, Arturas; Larralde, Martin; Yokochi, Masashi; Kobayashi, Naohiro; Porzel, Andrea; Griffin, Julian L; Viant, Mark R; Wishart, David S; Steinbeck, Christoph; Salek, Reza M; Neumann, Steffen
2018-01-02
NMR is a widely used analytical technique with a growing number of repositories available. As a result, demands for a vendor-agnostic, open data format for long-term archiving of NMR data have emerged with the aim to ease and encourage sharing, comparison, and reuse of NMR data. Here we present nmrML, an open XML-based exchange and storage format for NMR spectral data. The nmrML format is intended to be fully compatible with existing NMR data for chemical, biochemical, and metabolomics experiments. nmrML can capture raw NMR data, spectral data acquisition parameters, and where available spectral metadata, such as chemical structures associated with spectral assignments. The nmrML format is compatible with pure-compound NMR data for reference spectral libraries as well as NMR data from complex biomixtures, i.e., metabolomics experiments. To facilitate format conversions, we provide nmrML converters for Bruker, JEOL and Agilent/Varian vendor formats. In addition, easy-to-use Web-based spectral viewing, processing, and spectral assignment tools that read and write nmrML have been developed. Software libraries and Web services for data validation are available for tool developers and end-users. The nmrML format has already been adopted for capturing and disseminating NMR data for small molecules by several open source data processing tools and metabolomics reference spectral libraries, e.g., serving as storage format for the MetaboLights data repository. The nmrML open access data standard has been endorsed by the Metabolomics Standards Initiative (MSI), and we here encourage user participation and feedback to increase usability and make it a successful standard.
2015 Relaunch as Open Access Pediatric Neurology Briefs.
Millichap, John J; Millichap, J Gordon
2015-01-01
Pediatric Neurology Briefs (PNB) has been published monthly since 1987 as a continuing education service designed to expedite and facilitate review of current medical literature concerning pediatric neurology. In 2015, PNB is relaunched as an open access, peer-reviewed, journal with an expanded editorial board. PNB has a new website and content management system capable of organizing peer-review and providing improved indexing, DOI assignment, and online full-text article view. Digitization of back issues, archiving, and inclusion in PubMed are future goals. The new online open access PNB aims to reach more physicians, researchers, and other healthcare providers with highlights of the latest advances in pediatric neurology and commentaries by specialists in the field.
Emergency thoracotomy. Care of the patient in the OR: a case study.
Singer, N
1987-12-01
As an OR staff nurse at Cook County Hospital, some of my most challenging and rewarding nursing experiences have come from caring for emergency open-chest trauma patients. From the moment we receive a call that an open-chest patient is on the way, everyone assigned is in a high state of tension. Every decision takes on exaggerated importance. The circulating nurse, by virtue of his or her position during an emergency, is the "hub of the wheel" of activity. He or she is privy to all facets of care that are being administered to the patient. The nursing challenge of the emergency open-chest trauma is great, but it is not an impossible task.
Long-term comparison of endovascular and open repair of abdominal aortic aneurysm.
Lederle, Frank A; Freischlag, Julie A; Kyriakides, Tassos C; Matsumura, Jon S; Padberg, Frank T; Kohler, Ted R; Kougias, Panagiotis; Jean-Claude, Jessie M; Cikrit, Dolores F; Swanson, Kathleen M
2012-11-22
Whether elective endovascular repair of abdominal aortic aneurysm reduces long-term morbidity and mortality, as compared with traditional open repair, remains uncertain. We randomly assigned 881 patients with asymptomatic abdominal aortic aneurysms who were candidates for both procedures to either endovascular repair (444) or open repair (437) and followed them for up to 9 years (mean, 5.2). Patients were selected from 42 Veterans Affairs medical centers and were 49 years of age or older at the time of registration. More than 95% of the patients underwent the assigned repair. For the primary outcome of all-cause mortality, 146 deaths occurred in each group (hazard ratio with endovascular repair versus open repair, 0.97; 95% confidence interval [CI], 0.77 to 1.22; P=0.81). The previously reported reduction in perioperative mortality with endovascular repair was sustained at 2 years (hazard ratio, 0.63; 95% CI, 0.40 to 0.98; P=0.04) and at 3 years (hazard ratio, 0.72; 95% CI, 0.51 to 1.00; P=0.05) but not thereafter. There were 10 aneurysm-related deaths in the endovascular-repair group (2.3%) versus 16 in the open-repair group (3.7%) (P=0.22). Six aneurysm ruptures were confirmed in the endovascular-repair group versus none in the open-repair group (P=0.03). A significant interaction was observed between age and type of treatment (P=0.006); survival was increased among patients under 70 years of age in the endovascular-repair group but tended to be better among those 70 years of age or older in the open-repair group. Endovascular repair and open repair resulted in similar long-term survival. The perioperative survival advantage with endovascular repair was sustained for several years, but rupture after repair remained a concern. Endovascular repair led to increased long-term survival among younger patients but not among older patients, for whom a greater benefit from the endovascular approach had been expected. (Funded by the Department of Veterans Affairs Office of Research and Development; OVER ClinicalTrials.gov number, NCT00094575.).
Effects of subliminal backward-recorded messages on attitudes.
Swart, L C; Morgan, C L
1992-12-01
This study was designed to measure the effects of subliminal backward messages on attitudes. It was hypothesized that subliminal backward-recorded messages would influence the attitudes of listeners. Three subliminal backward-recorded messages from a popular song were used. 82 undergraduates were randomly assigned to one of four conditions: a three-message group heard a tape containing the backward messages recorded three times in succession, a six-message group heard a tape with the same backward messages recorded six times in succession, two control groups heard nonbackward recorded music. No statistically significant differences were found between the groups on a posttape attitude questionnaire. The results are discussed in terms of unconscious processing and the tricomponent theory of attitudes and attitude change.
17 CFR 16.01 - Trading volume, open contracts, prices, and critical dates.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Trading volume, open contracts... TRADING COMMISSION REPORTS BY REPORTING MARKETS § 16.01 Trading volume, open contracts, prices, and critical dates. (a) Trading volume and open contracts. Each reporting market shall record for each business...
17 CFR 16.01 - Trading volume, open contracts, prices, and critical dates.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Trading volume, open contracts... TRADING COMMISSION REPORTS BY REPORTING MARKETS § 16.01 Trading volume, open contracts, prices, and critical dates. (a) Trading volume and open contracts. Each reporting market shall record for each business...
ERIC Educational Resources Information Center
Hearn, James C.; McLendon, Michael K.; Gilchrist, Leigh Z.
2004-01-01
Sunshine laws are designed to make meetings and records of public entities visible so that a state can help ensure accountability of decision making affecting public resources. The laws often pit the news media's desire for greater public disclosure of information on public college and university governance against institutional leaders' desire to…
36 CFR 1256.24 - How long may access to some records be denied?
Code of Federal Regulations, 2010 CFR
2010-07-01
... many records are open for research, some records are closed for long periods, either under our general... with 44 U.S.C. 2108(b), we do not grant access to restricted census and survey records of the Bureau of...
36 CFR 1256.24 - How long may access to some records be denied?
Code of Federal Regulations, 2014 CFR
2014-07-01
... many records are open for research, some records are closed for long periods, either under our general... with 44 U.S.C. 2108(b), we do not grant access to restricted census and survey records of the Bureau of...
36 CFR 1256.24 - How long may access to some records be denied?
Code of Federal Regulations, 2012 CFR
2012-07-01
... many records are open for research, some records are closed for long periods, either under our general... with 44 U.S.C. 2108(b), we do not grant access to restricted census and survey records of the Bureau of...
15 CFR 990.45 - Administrative record.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 15 Commerce and Foreign Trade 3 2014-01-01 2014-01-01 false Administrative record. 990.45 Section... NATURAL RESOURCE DAMAGE ASSESSMENTS Preassessment Phase § 990.45 Administrative record. (a) If trustees decide to proceed with restoration planning, they must open a publicly available administrative record to...
15 CFR 990.45 - Administrative record.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 15 Commerce and Foreign Trade 3 2013-01-01 2013-01-01 false Administrative record. 990.45 Section... NATURAL RESOURCE DAMAGE ASSESSMENTS Preassessment Phase § 990.45 Administrative record. (a) If trustees decide to proceed with restoration planning, they must open a publicly available administrative record to...
15 CFR 990.45 - Administrative record.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 15 Commerce and Foreign Trade 3 2012-01-01 2012-01-01 false Administrative record. 990.45 Section... NATURAL RESOURCE DAMAGE ASSESSMENTS Preassessment Phase § 990.45 Administrative record. (a) If trustees decide to proceed with restoration planning, they must open a publicly available administrative record to...
Code of Federal Regulations, 2014 CFR
2014-01-01
... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Records. 1633.11 Section 1633.11 Commercial... (OPEN FLAME) OF MATTRESS SETS Rules and Regulations § 1633.11 Records. (a) Test and manufacturing records C general. Every manufacturer and any other person initially introducing into commerce mattress...
Code of Federal Regulations, 2012 CFR
2012-01-01
... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Records. 1633.11 Section 1633.11 Commercial... (OPEN FLAME) OF MATTRESS SETS Rules and Regulations § 1633.11 Records. (a) Test and manufacturing records C general. Every manufacturer and any other person initially introducing into commerce mattress...
ERIC Educational Resources Information Center
O'Brien, Walter
2015-01-01
One of the most difficult challenges of incorporating literacy in the classroom--as called for by the "Common Core State Standards" (NGAC and CCSSO 2010)--is inspiring reluctant writers. Students are often unmotivated by essay assignments or having to write answers to open-ended questions. Some students may even view these as obstacles…
Enhancing Classroom Creativity. Premier PD
ERIC Educational Resources Information Center
Luna, Elizabeth; Ernst, Jeremy; Clark, Aaron; DeLuca, V. William; Kelly, Daniel
2018-01-01
Educators often hear about the need for students to be more creative, more free-thinking, and more exploratory throughout projects and class assignments. This article will highlight the importance of creating and implementing an open-classroom environment where students are confident in their ability to ask questions and capable of exploring a…
Open-Ended Assignments and Student Responsibility
ERIC Educational Resources Information Center
Brauner, Annelie; Carey, Jannette; Henriksson, Marie; Sunnerhagen, Maria; Ehrenborg, Ewa
2007-01-01
An inquiry-based laboratory course was created in an effort to increase student responsibility in learning and to improve teaching in areas related to molecular medicine. Authentic medical cases with both scientific and clinical aspects formed the basis of a project-oriented course that also included student laboratory work focused on the…
Using a Commercial Simulator to Teach Sorption Separations
ERIC Educational Resources Information Center
Wankat, Phillip C.
2006-01-01
The commercial simulator Aspen Chromatography was used in the computer laboratory of a dual-level course. The lab assignments used a cookbook approach to teach basic simulator operation and open-ended exploration to understand adsorption. The students learned theory better than in previous years despite having less lecture time. Students agreed…
ERIC Educational Resources Information Center
Jago, Carol
2012-01-01
Great literature gives students a window to other places and times, but it often requires students to step outside their comfort zones and take on challenges they wouldn't usually attempt. Unfortunately, research shows that many schools are not assigning literature that pushes students beyond their current reading level. Jago encourages teachers…
Participation as Pedagogy: Student and Librarian Experiences of an Open Access Publishing Assignment
ERIC Educational Resources Information Center
Hicks, Alison
2017-01-01
Education for Instruction Librarians has traditionally centered upon the acquisition of practical classroom skills. While this approach has merit, from a sociocultural perspective of learning, student development emerges more completely through engagement with the communal activities and values that constitute professional practices rather than…
College Libraries and Student Culture: What We Now Know
ERIC Educational Resources Information Center
Duke, Lynda M., Ed.; Asher, Andrew D., Ed.
2012-01-01
How do college students "really" conduct research for classroom assignments? In 2008, five large Illinois universities were awarded a Library Services and Technology Act Grant to try to answer that question. The resulting ongoing study has already yielded some eye-opening results. The findings suggest changes ranging from simple…
78 FR 34354 - Privacy Act of 1974; System of Records
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-07
...(r) of the Privacy Act of 1974, as amended, was submitted on May 14, 2013, to the House Committee on... replace with ``System contains personnel data to support enlisted assignment, planning, programming...
Practices in NASA's EOSDIS to Promote Open Data and Research Integrity
NASA Astrophysics Data System (ADS)
Behnke, J.; Ramapriyan, H.
2017-12-01
The purpose of this paper is to highlight the key practices adopted by NASA in its Earth Observing System Data and Information System (EOSDIS) to promote and facilitate open data and research integrity. EOSDIS is the system that manages most of NASA's Earth science data from various sources - satellites, aircraft, field campaigns and some research projects. Since its inception in 1990 as a part of the Earth Observing System (EOS) Program, EOSDIS has been following NASA's free and open data and information policy, whereby data are shared with all users on a non-discriminatory basis and are provided at no cost. To ensure that the data are discoverable and accessible to the user community, NASA follows an evolutionary development approach, whereby the latest technologies that can be practically adopted are infused into EOSDIS. This results in continuous improvements in system capabilities such that technologies that users are accustomed to in other environments are brought to bear in their access to NASA's Earth observation data. Mechanisms have existed for ensuring that the data products offered by EOSDIS are vetted by the community before they are released. Information about data products such as Algorithm Theoretical Basis Documents and quality assessments are openly available with the products. The EOSDIS Distributed Active Archive Centers (DAACs) work with the science teams responsible for product generation to assist with proper use of metadata. The DAACs have knowledgeable staff to answer users' questions and have access to scientific experts as needed. Citation of data products in scientific papers are facilitated by assignment of Digital Object Identifiers (DOIs) - at present, over 50% of data products in EOSDIS have been assigned DOIs. NASA gathers and publishes citation metrics for the datasets offered by the DAACs. Through its Software and Services Citations Working Group, NASA is currently investigating broadening DOI assignments to promote greater provenance traceability. NASA has developed Preservation Content Specifications for Earth science data to ensure that provenance and context are captured and preserved for the future and is applying them to data and information from its missions. All these actions promote availability of information to promote integrity in scientific research.
Lóriga, Josmaily; Schmidt, Alexander R; Moran, Robbin C; Feldberg, Kathrin; Schneider, Harald; Heinrichs, Jochen
2014-09-01
• Closing gaps in the fossil record and elucidating phylogenetic relationships of mostly incomplete fossils are major challenges in the reconstruction of the diversification of fern lineages through time. The cosmopolitan family Dryopteridaceae represents one of the most species-rich families of leptosporangiate ferns, yet its fossil record is sparse and poorly understood. Here, we describe a fern inclusion in Miocene Dominican amber and investigate its relationships to extant Dryopteridaceae.• The morphology of the fossil was compared with descriptions of extant ferns, resulting in it being tentatively assigned to the bolbitidoid fern genus Elaphoglossum. This assignment was confirmed by reconstructing the evolution of the morphological characters preserved in the inclusion on a molecular phylogeny of 158 extant bolbitidoid ferns. To assess the morphology-based assignment of the fossil to Elaphoglossum, we examined DNA-calibrated divergence time estimates against the age of the amber deposits from which it came.• The fossil belongs to Elaphoglossum and is the first of a bolbitidoid fern. Its assignment to a particular section of Elaphoglossum could not be determined; however, sects. Lepidoglossa, Polytrichia, and Setosa can be discounted because the fossil lacks subulate scales or scales with acicular marginal hairs. Thus, the fossil might belong to either sects. Amygdalifolia, Wrightiana, Elaphoglossum, or Squamipedia or to an extinct lineage.• The discovery of a Miocene Elaphoglossum fossil provides remarkable support to current molecular clock-based estimates of the diversification of these ferns. © 2014 Botanical Society of America, Inc.
Oza, Shefali; Jazayeri, Darius; Teich, Jonathan M; Ball, Ellen; Nankubuge, Patricia Alexandra; Rwebembera, Job; Wing, Kevin; Sesay, Alieu Amara; Kanter, Andrew S; Ramos, Glauber D; Walton, David; Cummings, Rachael; Checchi, Francesco; Fraser, Hamish S
2017-08-21
Stringent infection control requirements at Ebola treatment centers (ETCs), which are specialized facilities for isolating and treating Ebola patients, create substantial challenges for recording and reviewing patient information. During the 2014-2016 West African Ebola epidemic, paper-based data collection systems at ETCs compromised the quality, quantity, and confidentiality of patient data. Electronic health record (EHR) systems have the potential to address such problems, with benefits for patient care, surveillance, and research. However, no suitable software was available for deployment when large-scale ETCs opened as the epidemic escalated in 2014. We present our work on rapidly developing and deploying OpenMRS-Ebola, an EHR system for the Kerry Town ETC in Sierra Leone. We describe our experience, lessons learned, and recommendations for future health emergencies. We used the OpenMRS platform and Agile software development approaches to build OpenMRS-Ebola. Key features of our work included daily communications between the development team and ground-based operations team, iterative processes, and phased development and implementation. We made design decisions based on the restrictions of the ETC environment and regular user feedback. To evaluate the system, we conducted predeployment user questionnaires and compared the EHR records with duplicate paper records. We successfully built OpenMRS-Ebola, a modular stand-alone EHR system with a tablet-based application for infectious patient wards and a desktop-based application for noninfectious areas. OpenMRS-Ebola supports patient tracking (registration, bed allocation, and discharge); recording of vital signs and symptoms; medication and intravenous fluid ordering and monitoring; laboratory results; clinician notes; and data export. It displays relevant patient information to clinicians in infectious and noninfectious zones. We implemented phase 1 (patient tracking; drug ordering and monitoring) after 2.5 months of full-time development. OpenMRS-Ebola was used for 112 patient registrations, 569 prescription orders, and 971 medication administration recordings. We were unable to fully implement phases 2 and 3 as the ETC closed because of a decrease in new Ebola cases. The phase 1 evaluation suggested that OpenMRS-Ebola worked well in the context of the rollout, and the user feedback was positive. To our knowledge, OpenMRS-Ebola is the most comprehensive adaptable clinical EHR built for a low-resource setting health emergency. It is designed to address the main challenges of data collection in highly infectious environments that require robust infection prevention and control measures and it is interoperable with other electronic health systems. Although we built and deployed OpenMRS-Ebola more rapidly than typical software, our work highlights the challenges of having to develop an appropriate system during an emergency rather than being able to rapidly adapt an existing one. Lessons learned from this and previous emergencies should be used to ensure that a set of well-designed, easy-to-use, pretested health software is ready for quick deployment in future. ©Shefali Oza, Darius Jazayeri, Jonathan M Teich, Ellen Ball, Patricia Alexandra Nankubuge, Job Rwebembera, Kevin Wing, Alieu Amara Sesay, Andrew S Kanter, Glauber D Ramos, David Walton, Rachael Cummings, Francesco Checchi, Hamish S Fraser. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 21.08.2017.
Exploring the effects of tape-recording on personality assessment.
Lichton, A I; Waehler, C A
1999-06-01
This study examined the possible influence of audio and video recording of personality assessment measures on anxiety. Undergraduate students in psychology were randomly assigned to Audiotape, Videotape, or Control conditions and given the State-Trait Anxiety Inventory and Rorschach Inkblot Method. A one-way multivariate analysis of variance indicated no significant differences among these conditions on the Spielberger, et al. State-Trait Anxiety Inventory, A-State scale, and five Rorschach measures of situational anxiety. Tape-recording itself did not seem to affect the anxiety indices of these frequently used personality assessments.
Openness to experience, work experience and patient safety.
Chang, Hao-Yuan; Friesner, Daniel; Lee, I-Chen; Chu, Tsung-Lan; Chen, Hui-Ling; Wu, Wan-Er; Teng, Ching-I
2016-11-01
The purpose of this study is to examine how the interaction between nurse openness and work experience is related to patient safety. No study has yet examined the interactions between these, and how openness and work experience jointly impact patient safety. This study adopts a cross-sectional design, using self-reported work experience, perceived time pressure and measures of patient safety, and was conducted in a major medical centre. The sample consisted of 421 full-time nurses from all available units in the centre. Proportionate random sampling was used. Patient safety was measured using the self-reported frequency of common adverse events. Openness was self-rated using items identified in the relevant literature. Nurse openness is positively related to the patient safety construct (B = 0.08, P = 0.03). Moreover, work experience reduces the relation between openness and patient safety (B = -0.12, P < 0.01). The relationship between openness, work experience and patient safety suggests a new means of improving patient care in a health system setting. Nurse managers may enhance patient safety by assessing nurse openness and assigning highly open nurses to duties that make maximum use of that trait. © 2016 John Wiley & Sons Ltd.
Machine-Assisted Translation in West Germany
1977-03-04
the Ger- man, English , French or Russian languages are recorded, where it is known that they have been used in translation or teaching assignments...German literary language encompasses about 300,000 words, English about 600,000, and the vocabulary of a person of average education is about...Terminology Recording and Evaluation Method ) was developed in the language service of the Siemens company in Munich as an aid for in-house application
Kanin, Maralee R; Pontrello, Jason K
2016-01-01
Calls to bring interdisciplinary content and examples into introductory science courses have increased, yet strategies that involve course restructuring often suffer from the need for a significant faculty commitment to motivate change. Minimizing the need for dramatic course reorganization, the structure, reactivity, and chemical biology applications of classes of biological monomers and polymers have been integrated into introductory organic chemistry courses through three series of semester-long weekly assignments that explored (a) Carbohydrates and Oligosaccharides, (b) Amino Acids, Peptides, and Proteins, and (c) Nucleosides, Nucleotides, and Nucleic Acids. Comparisons of unannounced pre- and post tests revealed improved understanding of a reaction introduced in the assignments, and course examinations evaluated cumulative assignment topics. Course surveys revealed that demonstrating biologically relevant applications consistently throughout the semesters enhanced student interest in the connection between basic organic chemistry content and its application to new and unfamiliar bio-related examples. Covering basic material related to these classes of molecules outside of the classroom opened lecture time to allow the instructor to further build on information developed through the weekly assignments, teaching advanced topics and applications typically not covered in an introductory organic chemistry lecture course. Assignments were implemented as homework, either with or without accompanying discussion, in both laboratory and lecture organic courses within the context of the existing course structures. © 2015 The International Union of Biochemistry and Molecular Biology.
36 CFR 1256.24 - How long may access to some records be denied?
Code of Federal Regulations, 2011 CFR
2011-07-01
... many records are open for research, some records are closed for long periods, either under our general... the Census less than 72 years old containing data identifying individuals enumerated in population...
Low-Carbohydrate Diet for the Treatment of Gestational Diabetes Mellitus
Moreno-Castilla, Cristina; Hernandez, Marta; Bergua, Merce; Alvarez, Maria C.; Arce, Maria A.; Rodriguez, Karen; Martinez-Alonso, Montserrat; Iglesias, Montserrat; Mateu, Magdalena; Santos, Maria D.; Pacheco, Linda R.; Blasco, Yolanda; Martin, Eva; Balsells, Nuria; Aranda, Nuria; Mauricio, Didac
2013-01-01
OBJECTIVE Medical nutrition therapy based on the control of the amount and distribution of carbohydrates (CHO) is the initial treatment for gestational diabetes mellitus (GDM), but there is a need for randomized controlled trials comparing different dietary strategies. The purpose of this study was to test the hypothesis that a low-CHO diet for the treatment of GDM would lead to a lower rate of insulin treatment with similar pregnancy outcomes compared with a control diet. RESEARCH DESIGN AND METHODS A total of 152 women with GDM were included in this open, randomized controlled trial and assigned to follow either a diet with low-CHO content (40% of the total diet energy content as CHO) or a control diet (55% of the total diet energy content as CHO). CHO intake was assessed by 3-day food records. The main pregnancy outcomes were also assessed. RESULTS The rate of women requiring insulin was not significantly different between the treatment groups (low CHO 54.7% vs. control 54.7%; P = 1). Daily food records confirmed a difference in the amount of CHO consumed between the groups (P = 0.0001). No differences were found in the obstetric and perinatal outcomes between the treatment groups. CONCLUSIONS Treatment of women with GDM using a low-CHO diet did not reduce the number of women needing insulin and produced similar pregnancy outcomes. In GDM, CHO amount (40 vs. 55% of calories) did not influence insulin need or pregnancy outcomes. PMID:23564917
Kavuluru, Ramakanth; Rios, Anthony; Lu, Yuan
2015-01-01
Background Diagnosis codes are assigned to medical records in healthcare facilities by trained coders by reviewing all physician authored documents associated with a patient's visit. This is a necessary and complex task involving coders adhering to coding guidelines and coding all assignable codes. With the popularity of electronic medical records (EMRs), computational approaches to code assignment have been proposed in the recent years. However, most efforts have focused on single and often short clinical narratives, while realistic scenarios warrant full EMR level analysis for code assignment. Objective We evaluate supervised learning approaches to automatically assign international classification of diseases (ninth revision) - clinical modification (ICD-9-CM) codes to EMRs by experimenting with a large realistic EMR dataset. The overall goal is to identify methods that offer superior performance in this task when considering such datasets. Methods We use a dataset of 71,463 EMRs corresponding to in-patient visits with discharge date falling in a two year period (2011–2012) from the University of Kentucky (UKY) Medical Center. We curate a smaller subset of this dataset and also use a third gold standard dataset of radiology reports. We conduct experiments using different problem transformation approaches with feature and data selection components and employing suitable label calibration and ranking methods with novel features involving code co-occurrence frequencies and latent code associations. Results Over all codes with at least 50 training examples we obtain a micro F-score of 0.48. On the set of codes that occur at least in 1% of the two year dataset, we achieve a micro F-score of 0.54. For the smaller radiology report dataset, the classifier chaining approach yields best results. For the smaller subset of the UKY dataset, feature selection, data selection, and label calibration offer best performance. Conclusions We show that datasets at different scale (size of the EMRs, number of distinct codes) and with different characteristics warrant different learning approaches. For shorter narratives pertaining to a particular medical subdomain (e.g., radiology, pathology), classifier chaining is ideal given the codes are highly related with each other. For realistic in-patient full EMRs, feature and data selection methods offer high performance for smaller datasets. However, for large EMR datasets, we observe that the binary relevance approach with learning-to-rank based code reranking offers the best performance. Regardless of the training dataset size, for general EMRs, label calibration to select the optimal number of labels is an indispensable final step. PMID:26054428
Kavuluru, Ramakanth; Rios, Anthony; Lu, Yuan
2015-10-01
Diagnosis codes are assigned to medical records in healthcare facilities by trained coders by reviewing all physician authored documents associated with a patient's visit. This is a necessary and complex task involving coders adhering to coding guidelines and coding all assignable codes. With the popularity of electronic medical records (EMRs), computational approaches to code assignment have been proposed in the recent years. However, most efforts have focused on single and often short clinical narratives, while realistic scenarios warrant full EMR level analysis for code assignment. We evaluate supervised learning approaches to automatically assign international classification of diseases (ninth revision) - clinical modification (ICD-9-CM) codes to EMRs by experimenting with a large realistic EMR dataset. The overall goal is to identify methods that offer superior performance in this task when considering such datasets. We use a dataset of 71,463 EMRs corresponding to in-patient visits with discharge date falling in a two year period (2011-2012) from the University of Kentucky (UKY) Medical Center. We curate a smaller subset of this dataset and also use a third gold standard dataset of radiology reports. We conduct experiments using different problem transformation approaches with feature and data selection components and employing suitable label calibration and ranking methods with novel features involving code co-occurrence frequencies and latent code associations. Over all codes with at least 50 training examples we obtain a micro F-score of 0.48. On the set of codes that occur at least in 1% of the two year dataset, we achieve a micro F-score of 0.54. For the smaller radiology report dataset, the classifier chaining approach yields best results. For the smaller subset of the UKY dataset, feature selection, data selection, and label calibration offer best performance. We show that datasets at different scale (size of the EMRs, number of distinct codes) and with different characteristics warrant different learning approaches. For shorter narratives pertaining to a particular medical subdomain (e.g., radiology, pathology), classifier chaining is ideal given the codes are highly related with each other. For realistic in-patient full EMRs, feature and data selection methods offer high performance for smaller datasets. However, for large EMR datasets, we observe that the binary relevance approach with learning-to-rank based code reranking offers the best performance. Regardless of the training dataset size, for general EMRs, label calibration to select the optimal number of labels is an indispensable final step. Copyright © 2015 Elsevier B.V. All rights reserved.
Open access intrapartum CTG database.
Chudáček, Václav; Spilka, Jiří; Burša, Miroslav; Janků, Petr; Hruban, Lukáš; Huptych, Michal; Lhotská, Lenka
2014-01-13
Cardiotocography (CTG) is a monitoring of fetal heart rate and uterine contractions. Since 1960 it is routinely used by obstetricians to assess fetal well-being. Many attempts to introduce methods of automatic signal processing and evaluation have appeared during the last 20 years, however still no significant progress similar to that in the domain of adult heart rate variability, where open access databases are available (e.g. MIT-BIH), is visible. Based on a thorough review of the relevant publications, presented in this paper, the shortcomings of the current state are obvious. A lack of common ground for clinicians and technicians in the field hinders clinically usable progress. Our open access database of digital intrapartum cardiotocographic recordings aims to change that. The intrapartum CTG database consists in total of 552 intrapartum recordings, which were acquired between April 2010 and August 2012 at the obstetrics ward of the University Hospital in Brno, Czech Republic. All recordings were stored in electronic form in the OB TraceVue®;system. The recordings were selected from 9164 intrapartum recordings with clinical as well as technical considerations in mind. All recordings are at most 90 minutes long and start a maximum of 90 minutes before delivery. The time relation of CTG to delivery is known as well as the length of the second stage of labor which does not exceed 30 minutes. The majority of recordings (all but 46 cesarean sections) is - on purpose - from vaginal deliveries. All recordings have available biochemical markers as well as some more general clinical features. Full description of the database and reasoning behind selection of the parameters is presented in the paper. A new open-access CTG database is introduced which should give the research community common ground for comparison of results on reasonably large database. We anticipate that after reading the paper, the reader will understand the context of the field from clinical and technical perspectives which will enable him/her to use the database and also understand its limitations.
Accommodating student learning styles and preferences in an online occupational therapy course.
Doyle, Nancy Wolcott; Jacobs, Karen
2013-01-01
Occupational therapy's online education must be research-based and inclusive. One way to provide a more inclusive online learning experience is to attend to individual learning styles and preferences. This study uses the best available evidence on learning styles and online education to develop, implement, and study occupational therapy students' experiences with an online learning module and related assignment. Eight students consented to take an online survey after completing a learning module and related assignment in an online post-professional graduate course in occupational therapy. The survey explored their learning experience and its applicability to clinical work. Data gathered from multiple-choice, Likert-scale, and open-ended questions were descriptively analyzed. Results from this study suggest that students find the study of learning styles and preferences enjoyable and applicable to their clinical work, but are often motivated by factors such as time and technology when selecting the format of a course assignment.
CoMoDo: identifying dynamic protein domains based on covariances of motion.
Wieninger, Silke A; Ullmann, G Matthias
2015-06-09
Most large proteins are built of several domains, compact units which enable functional protein motions. Different domain assignment approaches exist, which mostly rely on concepts of stability, folding, and evolution. We describe the automatic assignment method CoMoDo, which identifies domains based on protein dynamics. Covariances of atomic fluctuations, here calculated by an Elastic Network Model, are used to group residues into domains of different hierarchical levels. The so-called dynamic domains facilitate the study of functional protein motions involved in biological processes like ligand binding and signal transduction. By applying CoMoDo to a large number of proteins, we demonstrate that dynamic domains exhibit features absent in the commonly assigned structural domains, which can deliver insight into the interactions between domains and between subunits of multimeric proteins. CoMoDo is distributed as free open source software at www.bisb.uni-bayreuth.de/CoMoDo.html .
13Check_RNA: A tool to evaluate 13C chemical shifts assignments of RNA.
Icazatti, A A; Martin, O A; Villegas, M; Szleifer, I; Vila, J A
2018-06-19
Chemical shifts (CS) are an important source of structural information of macromolecules such as RNA. In addition to the scarce availability of CS for RNA, the observed values are prone to errors due to a wrong re-calibration or miss assignments. Different groups have dedicated their efforts to correct CS systematic errors on RNA. Despite this, there are not automated and freely available algorithms for correct assignments of RNA 13C CS before their deposition to the BMRB or re-reference already deposited CS with systematic errors. Based on an existent method we have implemented an open source python module to correct 13C CS (from here on 13Cexp) systematic errors of RNAs and then return the results in 3 formats including the nmrstar one. This software is available on GitHub at https://github.com/BIOS-IMASL/13Check_RNA under a MIT license. Supplementary data are available at Bioinformatics online.
Open source electronic health records and chronic disease management
Goldwater, Jason C; Kwon, Nancy J; Nathanson, Ashley; Muckle, Alison E; Brown, Alexa; Cornejo, Kerri
2014-01-01
Objective To study and report on the use of open source electronic health records (EHR) to assist with chronic care management within safety net medical settings, such as community health centers (CHC). Methods and Materials The study was conducted by NORC at the University of Chicago from April to September 2010. The NORC team undertook a comprehensive environmental scan, including a literature review, a dozen key informant interviews using a semistructured protocol, and a series of site visits to CHC that currently use an open source EHR. Results Two of the sites chosen by NORC were actively using an open source EHR to assist in the redesign of their care delivery system to support more effective chronic disease management. This included incorporating the chronic care model into an CHC and using the EHR to help facilitate its elements, such as care teams for patients, in addition to maintaining health records on indigent populations, such as tuberculosis status on homeless patients. Discussion The ability to modify the open-source EHR to adapt to the CHC environment and leverage the ecosystem of providers and users to assist in this process provided significant advantages in chronic care management. Improvements in diabetes management, controlled hypertension and increases in tuberculosis vaccinations were assisted through the use of these open source systems. Conclusions The flexibility and adaptability of open source EHR demonstrated its utility and viability in the provision of necessary and needed chronic disease care among populations served by CHC. PMID:23813566
Patient Electronic Health Records as a Means to Approach Genetic Research in Gastroenterology
Ananthakrishnan, Ashwin N; Lieberman, David
2015-01-01
Electronic health records (EHR) are being increasingly utilized and form a unique source of extensive data gathered during routine clinical care. Through use of codified and free text concepts identified using clinical informatics tools, disease labels can be assigned with a high degree of accuracy. Analysis linking such EHR-assigned disease labels to a biospecimen repository has demonstrated that genetic associations identified in prospective cohorts can be replicated with adequate statistical power, and novel phenotypic associations identified. In addition, genetic discovery research can be performed utilizing clinical, laboratory, and procedure data obtained during care. Challenges with such research include the need to tackle variability in quality and quantity of EHR data and importance of maintaining patient privacy and data security. With appropriate safeguards, this novel and emerging field of research offers considerable promise and potential to further scientific research in gastroenterology efficiently, cost-effectively, and with engagement of patients and communities. PMID:26073373
Code of Federal Regulations, 2013 CFR
2013-01-01
... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Records. § 1633.11 Section § 1633.11... FLAMMABILITY (OPEN FLAME) OF MATTRESS SETS Rules and Regulations § 1633.11 Records. (a) Test and manufacturing records C general. Every manufacturer and any other person initially introducing into commerce mattress...
Kasthurirathne, Suranga N; Mamlin, Burke; Grieve, Grahame; Biondich, Paul
2015-01-01
Interoperability is essential to address limitations caused by the ad hoc implementation of clinical information systems and the distributed nature of modern medical care. The HL7 V2 and V3 standards have played a significant role in ensuring interoperability for healthcare. FHIR is a next generation standard created to address fundamental limitations in HL7 V2 and V3. FHIR is particularly relevant to OpenMRS, an Open Source Medical Record System widely used across emerging economies. FHIR has the potential to allow OpenMRS to move away from a bespoke, application specific API to a standards based API. We describe efforts to design and implement a FHIR based API for the OpenMRS platform. Lessons learned from this effort were used to define long term plans to transition from the legacy OpenMRS API to a FHIR based API that greatly reduces the learning curve for developers and helps enhance adhernce to standards.
Antisymmetric Amino-Wagging Band of Hydrazine up toK‧ = 13 Levels
NASA Astrophysics Data System (ADS)
Gulaczyk, Iwona; Kre, Marek; Valentin, Alain
1997-12-01
A newly recorded high-resolution infrared spectrum of hydrazine has been studied in the 729-1198 cm-1region (the ν12antisymmetric wagging band) with a resolution of 0.002 cm-1. About 1350 transitions withK‧ from 7 to 13 have been newly assigned and about 2350 transitions with lower values ofK‧ reanalyzed with the improved precision. The effective parameters have been calculated separately for each value ofK‧ using the Hougen-Ohashi hamiltonian for hydrazine. The extended assignment completes the analysis of the ν12band of hydrazine.
Multistate and multihypothesis discrimination with open quantum systems
NASA Astrophysics Data System (ADS)
Kiilerich, Alexander Holm; Mølmer, Klaus
2018-05-01
We show how an upper bound for the ability to discriminate any number N of candidates for the Hamiltonian governing the evolution of an open quantum system may be calculated by numerically efficient means. Our method applies an effective master-equation analysis to evaluate the pairwise overlaps between candidate full states of the system and its environment pertaining to the Hamiltonians. These overlaps are then used to construct an N -dimensional representation of the states. The optimal positive-operator valued measure (POVM) and the corresponding probability of assigning a false hypothesis may subsequently be evaluated by phrasing optimal discrimination of multiple nonorthogonal quantum states as a semidefinite programming problem. We provide three realistic examples of multihypothesis testing with open quantum systems.
Schöffski, Patrick; Chawla, Sant; Maki, Robert G; Italiano, Antoine; Gelderblom, Hans; Choy, Edwin; Grignani, Giovanni; Camargo, Veridiana; Bauer, Sebastian; Rha, Sun Young; Blay, Jean-Yves; Hohenberger, Peter; D'Adamo, David; Guo, Matthew; Chmielowski, Bartosz; Le Cesne, Axel; Demetri, George D; Patel, Shreyaskumar R
2016-04-16
A non-randomised, phase 2 study showed activity and tolerability of eribulin in advanced or metastatic soft-tissue sarcoma. In this phase 3 study, we aimed to compare overall survival in patients with advanced or metastatic soft-tissue sarcoma who received eribulin with that in patients who received dacarbazine (an active control). We did this randomised, open-label, phase 3 study across 110 study sites in 22 countries. We enrolled patients aged 18 years or older with intermediate-grade or high-grade advanced liposarcoma or leiomyosarcoma who had received at least two previous systemic regimens for advanced disease (including an anthracycline). Using an interactive voice and web response system, an independent statistician randomly assigned (1:1) patients to receive eribulin mesilate (1·4 mg/m(2) intravenously on days 1 and 8) or dacarbazine (850 mg/m(2), 1000 mg/m(2), or 1200 mg/m(2) [dose dependent on centre and clinician] intravenously on day 1) every 21 days until disease progression. Randomisation was stratified by disease type, geographical region, and number of previous regimens for advanced soft-tissue sarcoma and in blocks of six. Patients and investigators were not masked to treatment assignment. The primary endpoint was overall survival in the intention-to-treat population. The study is registered with ClinicalTrials.gov, number NCT01327885, and is closed to recruitment, but treatment and follow-up continue. Between March 10, 2011 and May 22, 2013, we randomly assigned patients to eribulin (n=228) or dacarbazine (n=224). Overall survival was significantly improved in patients assigned to eribulin compared with those assigned to dacarbazine (median 13·5 months [95% CI 10·9-15·6] vs 11·5 months [9·6-13·0]; hazard ratio 0·77 [95% CI 0·62-0·95]; p=0·0169). Treatment-emergent adverse events occurred in 224 (99%) of 226 patients who received eribulin and 218 (97%) of 224 who received dacarbazine. Grade 3 or higher adverse events were more common in patients who received eribulin (152 [67%]) than in those who received dacarbazine (126 [56%]), as were deaths (10 [4%] vs 3 [1%]); one death (in the eribulin group) was considered treatment-related by the investigators. Overall survival was improved in patients assigned to eribulin compared with those assigned to an active control, suggesting that eribulin could be a treatment option for advanced soft-tissue sarcoma. Eisai. Copyright © 2016 Elsevier Ltd. All rights reserved.
BioAcoustica: a free and open repository and analysis platform for bioacoustics
Baker, Edward; Price, Ben W.; Rycroft, S. D.; Smith, Vincent S.
2015-01-01
We describe an online open repository and analysis platform, BioAcoustica (http://bio.acousti.ca), for recordings of wildlife sounds. Recordings can be annotated using a crowdsourced approach, allowing voice introductions and sections with extraneous noise to be removed from analyses. This system is based on the Scratchpads virtual research environment, the BioVeL portal and the Taverna workflow management tool, which allows for analysis of recordings using a grid computing service. At present the analyses include spectrograms, oscillograms and dominant frequency analysis. Further analyses can be integrated to meet the needs of specific researchers or projects. Researchers can upload and annotate their recordings to supplement traditional publication. Database URL: http://bio.acousti.ca PMID:26055102
10 CFR Appendix A to Part 820 - General Statement of Enforcement Policy
Code of Federal Regulations, 2012 CFR
2012-01-01
... evaluated in the aggregate and a single severity level assigned for a group of violations. (c) Isolated... pre-decisional discussions regarding potential or alleged violations and will not normally be open to... forth the conclusion of the DOE Office of Nuclear Safety and Environment that one or more violations of...
10 CFR Appendix A to Part 820 - General Statement of Enforcement Policy
Code of Federal Regulations, 2014 CFR
2014-01-01
... evaluated in the aggregate and a single severity level assigned for a group of violations. (c) Isolated... pre-decisional discussions regarding potential or alleged violations and will not normally be open to... forth the conclusion of the DOE Office of Nuclear Safety and Environment that one or more violations of...
10 CFR Appendix A to Part 820 - General Statement of Enforcement Policy
Code of Federal Regulations, 2010 CFR
2010-01-01
... evaluated in the aggregate and a single severity level assigned for a group of violations. (c) Isolated... pre-decisional discussions regarding potential or alleged violations and will not normally be open to... forth the conclusion of the DOE Office of Nuclear Safety and Environment that one or more violations of...
10 CFR Appendix A to Part 820 - General Statement of Enforcement Policy
Code of Federal Regulations, 2013 CFR
2013-01-01
... evaluated in the aggregate and a single severity level assigned for a group of violations. (c) Isolated... pre-decisional discussions regarding potential or alleged violations and will not normally be open to... forth the conclusion of the DOE Office of Nuclear Safety and Environment that one or more violations of...
10 CFR Appendix A to Part 820 - General Statement of Enforcement Policy
Code of Federal Regulations, 2011 CFR
2011-01-01
... evaluated in the aggregate and a single severity level assigned for a group of violations. (c) Isolated... pre-decisional discussions regarding potential or alleged violations and will not normally be open to... forth the conclusion of the DOE Office of Nuclear Safety and Environment that one or more violations of...
Exploring Students' Engineering Designs through Open-Ended Assignments
ERIC Educational Resources Information Center
Puente, S. M. Gómez; Jansen, J. W.
2017-01-01
This paper aims at presenting the experience of the Power Conversion project in teaching students to design a proof-of-principle contactless energy transfer system for the charging of electrical vehicles. The Power Conversion is a second-year electrical engineering (EE) project in which students are to gather and apply EE knowledge to design and…
Implementing a Learning Model for a Practical Subject in Distance Education.
ERIC Educational Resources Information Center
Weller, M. J.; Hopgood, A. A.
1997-01-01
Artificial Intelligence for Technology, a distance learning course at the Open University, is based on a learning model that combines conceptualization, construction, and dialog. This allows a practical emphasis which has been difficult to implement in distance education. The course uses commercial software, real-world-based assignments, and a…
Designing Tasks for Math Modeling in College Algebra: A Critical Review
ERIC Educational Resources Information Center
Staats, Susan; Robertson, Douglas
2014-01-01
Over the last decade, the pedagogical approach known as mathematical modeling has received increased interest in college algebra classes in the United States. Math modeling assignments ask students to develop their own problem-solving tools to address non-routine, realistic scenarios. The open-ended quality of modeling activities creates dilemmas…
77 FR 16033 - Sunshine Act Meeting; Open Commission Meeting; Wednesday, March 21, 2012
Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-19
...., Transferors, and Liberty Media Corporation, Transferee, for Authority to Transfer Control (MB Docket No. 07-18) and Applications for Consent to the Assignment and/or Transfer of Control of Licenses, Adelphia.... 2 MEDIA Title: Creation of a Low Power Radio Service (MM Docket No. 99-25) and Amendment of Service...
Dualism and Vocational Education and Training: Creating the People Who Require Training
ERIC Educational Resources Information Center
Zoellner, Don
2012-01-01
Governments in advanced liberal democracies have assigned Vocational Education and Training (VET) a critical role in preparing a productive workforce for the broader economy. This linkage opens the way to use economic theories to expand the understanding of VET. Noted economic theorists have described the use of one economic reductionist technique…
ERIC Educational Resources Information Center
Wang, Hanrong; Tang, Yingqi; Knight, Carley
2010-01-01
This study analyzes job advertisements to identify the contemporary development of academic reference librarianship in the United States. Results show that more job openings, higher educational backgrounds, more duties & responsibilities, and variety of titles were assigned to academic reference librarian positions from 1966 through 2009.…
Why Does My Cruorine Change Color? Using Classic Research Articles To Teach Biochemistry Topics.
ERIC Educational Resources Information Center
White, Harold B., III
2001-01-01
Uses the spectroscopic study by G.G. Stokes of the reversible "oxidation and reduction" of hemoglobin to illustrate how a series of open-ended group assignments and associated classroom demonstrations can be built around a single article in a way that integrates and illuminates basic concepts. (Author/MM)
ERIC Educational Resources Information Center
Regalla, Michele; Davies, Alex; Grissom, Donita; Losavio, Antonio
2018-01-01
This study investigates a service-learning program for university students seeking teacher certification examined through the lens of sociocultural theory. Data was collected from teacher candidates (TCs) in the form of surveys and an open-ended writing assignment. Administrators from the partner schools were also interviewed to provide their…
EFL Writing Revision with Blind Expert and Peer Review Using a CMC Open Forum
ERIC Educational Resources Information Center
Wu, Wen-Chi Vivian; Petit, Emily; Chen, Ching-Huei
2015-01-01
This exploratory computer assisted-language learning (CALL) study used a computer-mediated communication (CMC) interface to allow English as a foreign language (EFL) writing students in classes at two universities to give each other anonymous peer feedback about essay-writing assignments reacting to selected news stories. Experts also provided…
Using a Video Game to Teach Supply Chain and Logistics Management
ERIC Educational Resources Information Center
Liu, Chiung-Lin
2017-01-01
This study used OpenTTD, a video game that supports in-depth experiential learning, to evaluate undergraduate students' opinions regarding supply chain and logistics management learning. The 101 undergraduate participants were assigned to either an experimental group or a control group. From the post-test questionnaires, the analytical results…
ERIC Educational Resources Information Center
Macdonald, Ian S.; Bullen, Mark; Kozak, R. A.
2007-01-01
This study investigated appropriate pedagogical techniques for workplace e-learning programs in the South African wood products (furniture) manufacturing sector. The study found that learners responded favourably to constructivist teaching approaches, such as asynchronous discussions, open-ended task-based activities, and assignments incorporating…
Evolution of Protein Lipograms: A Bioinformatics Problem
ERIC Educational Resources Information Center
White, Harold B., III; Dhurjati, Prasad
2006-01-01
A protein lacking one of the 20 common amino acids is a protein lipogram. This open-ended problem-based learning assignment deals with the evolution of proteins with biased amino acid composition. It has students query protein and metabolic databases to test the hypothesis that natural selection has reduced the frequency of each amino acid…
Examining Student Heuristic Usage in a Hydrogen Bonding Assessment
ERIC Educational Resources Information Center
Miller, Kathryn; Kim, Thomas
2017-01-01
This study investigates the role of representational competence in student responses to an assessment of hydrogen bonding. The assessment couples the use of a multiple-select item ("Choose all that apply") with an open-ended item to allow for an examination of students' cognitive processes as they relate to the assignment of hydrogen…
2014-06-01
CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Robert Jensen, Daniel DeSchepper, David Flanagan, Wendy Kosik...lessons learned , or research purposes; these are generally long-term records.” Records will be kept in physical laboratory notebooks and digitally... learned ” could have potential value in addressing future research focus. Testing progression protocols beyond the third tier are intended for ARL
An open access database for the evaluation of heart sound algorithms.
Liu, Chengyu; Springer, David; Li, Qiao; Moody, Benjamin; Juan, Ricardo Abad; Chorro, Francisco J; Castells, Francisco; Roig, José Millet; Silva, Ikaro; Johnson, Alistair E W; Syed, Zeeshan; Schmidt, Samuel E; Papadaniil, Chrysa D; Hadjileontiadis, Leontios; Naseri, Hosein; Moukadem, Ali; Dieterlen, Alain; Brandt, Christian; Tang, Hong; Samieinasab, Maryam; Samieinasab, Mohammad Reza; Sameni, Reza; Mark, Roger G; Clifford, Gari D
2016-12-01
In the past few decades, analysis of heart sound signals (i.e. the phonocardiogram or PCG), especially for automated heart sound segmentation and classification, has been widely studied and has been reported to have the potential value to detect pathology accurately in clinical applications. However, comparative analyses of algorithms in the literature have been hindered by the lack of high-quality, rigorously validated, and standardized open databases of heart sound recordings. This paper describes a public heart sound database, assembled for an international competition, the PhysioNet/Computing in Cardiology (CinC) Challenge 2016. The archive comprises nine different heart sound databases sourced from multiple research groups around the world. It includes 2435 heart sound recordings in total collected from 1297 healthy subjects and patients with a variety of conditions, including heart valve disease and coronary artery disease. The recordings were collected from a variety of clinical or nonclinical (such as in-home visits) environments and equipment. The length of recording varied from several seconds to several minutes. This article reports detailed information about the subjects/patients including demographics (number, age, gender), recordings (number, location, state and time length), associated synchronously recorded signals, sampling frequency and sensor type used. We also provide a brief summary of the commonly used heart sound segmentation and classification methods, including open source code provided concurrently for the Challenge. A description of the PhysioNet/CinC Challenge 2016, including the main aims, the training and test sets, the hand corrected annotations for different heart sound states, the scoring mechanism, and associated open source code are provided. In addition, several potential benefits from the public heart sound database are discussed.
33 CFR 1.20-1 - Testimony by Coast Guard personnel and production of records.
Code of Federal Regulations, 2012 CFR
2012-07-01
... each Maintenance and Logistics Command, each District Legal Officer, and the Legal Officer assigned to... should be made to the District Legal Officer serving the geographic area where the former member or...
33 CFR 1.20-1 - Testimony by Coast Guard personnel and production of records.
Code of Federal Regulations, 2014 CFR
2014-07-01
... each Maintenance and Logistics Command, each District Legal Officer, and the Legal Officer assigned to... should be made to the District Legal Officer serving the geographic area where the former member or...
33 CFR 1.20-1 - Testimony by Coast Guard personnel and production of records.
Code of Federal Regulations, 2010 CFR
2010-07-01
... each Maintenance and Logistics Command, each District Legal Officer, and the Legal Officer assigned to... should be made to the District Legal Officer serving the geographic area where the former member or...
33 CFR 1.20-1 - Testimony by Coast Guard personnel and production of records.
Code of Federal Regulations, 2013 CFR
2013-07-01
... each Maintenance and Logistics Command, each District Legal Officer, and the Legal Officer assigned to... should be made to the District Legal Officer serving the geographic area where the former member or...
33 CFR 1.20-1 - Testimony by Coast Guard personnel and production of records.
Code of Federal Regulations, 2011 CFR
2011-07-01
... each Maintenance and Logistics Command, each District Legal Officer, and the Legal Officer assigned to... should be made to the District Legal Officer serving the geographic area where the former member or...
Code of Federal Regulations, 2010 CFR
2010-01-01
... International Registry affecting United States civil aircraft, aircraft assigned a U.S. registration number and... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT RECORDING OF AIRCRAFT TITLES AND SECURITY DOCUMENTS Transmission of Information to the International Registry § 49.61...
Code of Federal Regulations, 2012 CFR
2012-01-01
... International Registry affecting United States civil aircraft, aircraft assigned a U.S. registration number and... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT RECORDING OF AIRCRAFT TITLES AND SECURITY DOCUMENTS Transmission of Information to the International Registry § 49.61...
Code of Federal Regulations, 2011 CFR
2011-01-01
... International Registry affecting United States civil aircraft, aircraft assigned a U.S. registration number and... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT RECORDING OF AIRCRAFT TITLES AND SECURITY DOCUMENTS Transmission of Information to the International Registry § 49.61...
Code of Federal Regulations, 2014 CFR
2014-01-01
... International Registry affecting United States civil aircraft, aircraft assigned a U.S. registration number and... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT RECORDING OF AIRCRAFT TITLES AND SECURITY DOCUMENTS Transmission of Information to the International Registry § 49.61...
Code of Federal Regulations, 2013 CFR
2013-01-01
... International Registry affecting United States civil aircraft, aircraft assigned a U.S. registration number and... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT RECORDING OF AIRCRAFT TITLES AND SECURITY DOCUMENTS Transmission of Information to the International Registry § 49.61...
High School Open On-Line Courses (HOOC): A Case Study from Italy
ERIC Educational Resources Information Center
Canessa, Enrique; Pisani, Armando
2013-01-01
The first implementation of complete high school, open on-line courses (HOOC) aiming to support the training and basic scientific knowledge of young students from the Liceo Ginnasio Dante Alighieri in Gorizia, Italy, is discussed. Using the open source and automated recording system openEyA, HOOC give a student the opportunity to watch on-line, at…
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Unsupervised laparoscopic appendicectomy by surgical trainees is safe and time-effective.
Wong, Kenneth; Duncan, Tristram; Pearson, Andrew
2007-07-01
Open appendicectomy is the traditional standard treatment for appendicitis. Laparoscopic appendicectomy is perceived as a procedure with greater potential for complications and longer operative times. This paper examines the hypothesis that unsupervised laparoscopic appendicectomy by surgical trainees is a safe and time-effective valid alternative. Medical records, operating theatre records and histopathology reports of all patients undergoing laparoscopic and open appendicectomy over a 15-month period in two hospitals within an area health service were retrospectively reviewed. Data were analysed to compare patient features, pathology findings, operative times, complications, readmissions and mortality between laparoscopic and open groups and between unsupervised surgical trainee operators versus consultant surgeon operators. A total of 143 laparoscopic and 222 open appendicectomies were reviewed. Unsupervised trainees performed 64% of the laparoscopic appendicectomies and 55% of the open appendicectomies. There were no significant differences in complication rates, readmissions, mortality and length of stay between laparoscopic and open appendicectomy groups or between trainee and consultant surgeon operators. Conversion rates (laparoscopic to open approach) were similar for trainees and consultants. Unsupervised senior surgical trainees did not take significantly longer to perform laparoscopic appendicectomy when compared to unsupervised trainee-performed open appendicectomy. Unsupervised laparoscopic appendicectomy by surgical trainees is safe and time-effective.
Anisotropy in Fracking: A Percolation Model for Observed Microseismicity
NASA Astrophysics Data System (ADS)
Norris, J. Quinn; Turcotte, Donald L.; Rundle, John B.
2015-01-01
Hydraulic fracturing (fracking), using high pressures and a low viscosity fluid, allow the extraction of large quantiles of oil and gas from very low permeability shale formations. The initial production of oil and gas at depth leads to high pressures and an extensive distribution of natural fractures which reduce the pressures. With time these fractures heal, sealing the remaining oil and gas in place. High volume fracking opens the healed fractures allowing the oil and gas to flow to horizontal production wells. We model the injection process using invasion percolation. We use a 2D square lattice of bonds to model the sealed natural fractures. The bonds are assigned random strengths and the fluid, injected at a point, opens the weakest bond adjacent to the growing cluster of opened bonds. Our model exhibits burst dynamics in which the clusters extend rapidly into regions with weak bonds. We associate these bursts with the microseismic activity generated by fracking injections. A principal object of this paper is to study the role of anisotropic stress distributions. Bonds in the y-direction are assigned higher random strengths than bonds in the x-direction. We illustrate the spatial distribution of clusters and the spatial distribution of bursts (small earthquakes) for several degrees of anisotropy. The results are compared with observed distributions of microseismicity in a fracking injection. Both our bursts and the observed microseismicity satisfy Gutenberg-Richter frequency-size statistics.
Poirier, Josée; Bennett, Wendy L; Jerome, Gerald J; Shah, Nina G; Lazo, Mariana; Yeh, Hsin-Chieh; Clark, Jeanne M; Cobb, Nathan K
2016-02-09
The benefits of physical activity are well documented, but scalable programs to promote activity are needed. Interventions that assign tailored and dynamically adjusting goals could effect significant increases in physical activity but have not yet been implemented at scale. Our aim was to examine the effectiveness of an open access, Internet-based walking program that assigns daily step goals tailored to each participant. A two-arm, pragmatic randomized controlled trial compared the intervention to no treatment. Participants were recruited from a workplace setting and randomized to a no-treatment control (n=133) or to treatment (n=132). Treatment participants received a free wireless activity tracker and enrolled in the walking program, Walkadoo. Assessments were fully automated: activity tracker recorded primary outcomes (steps) without intervention by the participant or investigators. The two arms were compared on change in steps per day from baseline to follow-up (after 6 weeks of treatment) using a two-tailed independent samples t test. Participants (N=265) were 66.0% (175/265) female with an average age of 39.9 years. Over half of the participants (142/265, 53.6%) were sedentary (<5000 steps/day) and 44.9% (119/265) were low to somewhat active (5000-9999 steps/day). The intervention group significantly increased their steps by 970 steps/day over control (P<.001), with treatment effects observed in sedentary (P=.04) and low-to-somewhat active (P=.004) participants alike. The program is effective in increasing daily steps. Participants benefited from the program regardless of their initial activity level. A tailored, adaptive approach using wireless activity trackers is realistically implementable and scalable. Clinicaltrials.gov NCT02229409, https://clinicaltrials.gov/ct2/show/NCT02229409 (Archived by WebCite at http://www.webcitation.org/6eiWCvBYe).
Wiklund, Helena; Taylor, John D.; Dahlgren, Thomas G.; Todt, Christiane; Ikebe, Chiho; Rabone, Muriel; Glover, Adrian G.
2017-01-01
Abstract We present the first DNA taxonomy publication on abyssal Mollusca from the Clarion-Clipperton Zone (CCZ), central Pacific ocean, using material collected as part of the Abyssal Baseline (ABYSSLINE) environmental survey cruise ‘AB01’ to the UK Seabed Resources Ltd (UKSRL) polymetallic-nodule exploration area ‘UK-1’ in the eastern CCZ. This is the third paper in a series to provide regional taxonomic data for a region that is undergoing intense deep-sea mineral exploration for high-grade polymetallic nodules. Taxonomic data are presented for 21 species from 42 records identified by a combination of morphological and genetic data, including molecular phylogenetic analyses. These included 3 heterodont bivalves, 5 protobranch bivalves, 4 pteriomorph bivalves, 1 caudofoveate, 1 monoplacophoran, 1 polyplacophoran, 4 scaphopods and 2 solenogastres. Gastropoda were recovered but will be the subject of a future study. Seven taxa matched published morphological descriptions for species with deep Pacific type localities, and our sequences provide the first genetic data for these taxa. One taxon morphologically matched a known cosmopolitan species but with a type locality in a different ocean basin and was assigned the open nomenclature ‘cf’ as a precautionary approach in taxon assignments to avoid over-estimating species ranges. One taxon is here described as a new species, Ledella knudseni sp. n. For the remaining 12 taxa, we have determined them to be potentially new species, for which we make the raw data, imagery and vouchers available for future taxonomic study. The Clarion-Clipperton Zone is a region undergoing intense exploration for potential deep-sea mineral extraction. We present these data to facilitate future taxonomic and environmental impact study by making both data and voucher materials available through curated and accessible biological collections. PMID:29118626
Effectiveness of Nursing Process Use in Primary Care.
Pérez Rivas, Francisco Javier; Martín-Iglesias, Susana; Pacheco del Cerro, José Luis; Minguet Arenas, Cristina; García López, Montserrat; Beamud Lagos, Milagros
2016-01-01
To determine whether patients assigned to primary care nurses who use the nursing process (use of NANDA-I, NIC, and NOC) achieve better intermediate health outcomes than the population assigned to nurses who do not use the nursing process. This is a retrospective cross-sectional study conducted in 34 primary healthcare centers of Area 11 of the Community of Madrid (Spain) based on electronic health records. The extension of health care provided was greater in nurses who used the nursing process. Patients assigned to these nurses have better control of their chronic diseases and incur lower drug costs. The use of the nursing process can lead to improved health of populations. The development of strategies is necessary to ensure greater use of the nursing process among nurses in primary care. © 2015 NANDA International, Inc.
NeCamp, Timothy; Kilbourne, Amy; Almirall, Daniel
2017-08-01
Cluster-level dynamic treatment regimens can be used to guide sequential treatment decision-making at the cluster level in order to improve outcomes at the individual or patient-level. In a cluster-level dynamic treatment regimen, the treatment is potentially adapted and re-adapted over time based on changes in the cluster that could be impacted by prior intervention, including aggregate measures of the individuals or patients that compose it. Cluster-randomized sequential multiple assignment randomized trials can be used to answer multiple open questions preventing scientists from developing high-quality cluster-level dynamic treatment regimens. In a cluster-randomized sequential multiple assignment randomized trial, sequential randomizations occur at the cluster level and outcomes are observed at the individual level. This manuscript makes two contributions to the design and analysis of cluster-randomized sequential multiple assignment randomized trials. First, a weighted least squares regression approach is proposed for comparing the mean of a patient-level outcome between the cluster-level dynamic treatment regimens embedded in a sequential multiple assignment randomized trial. The regression approach facilitates the use of baseline covariates which is often critical in the analysis of cluster-level trials. Second, sample size calculators are derived for two common cluster-randomized sequential multiple assignment randomized trial designs for use when the primary aim is a between-dynamic treatment regimen comparison of the mean of a continuous patient-level outcome. The methods are motivated by the Adaptive Implementation of Effective Programs Trial which is, to our knowledge, the first-ever cluster-randomized sequential multiple assignment randomized trial in psychiatry.
NASA Astrophysics Data System (ADS)
Gurzhiy, Vladislav V.; Tyumentseva, Olga S.; Britvin, Sergey N.; Krivovichev, Sergey V.; Tananaev, Ivan G.
2018-01-01
Three novel uranyl selenate and sulfate oxysalts templated by protonated azetidine molecules, [AzH]+, and its ring-opened counterpart 1-azetidinepropanamine, [AzH(CH2)3NH3]2+, have been prepared and studied by X-ray structural analysis. Conformations of azetidinium cations were analysed by means of infrared vibrational assignments supported by the DFT calculations. Crystallization of [AzH]2 [(UO2)2(SeO4)3(H2O)] (I) from highly acidic solutions suggests that low pH does not necessarily result in the opening of azetidine ring. [AzH(CH2)3NH3][(UO2)2(SeO4)3(H2O)](H2O) (II) and [AzH(CH2)3NH3](H5O2)[(UO2)2(SO4)3(HSO4)] (III) are the first structurally characterized crystalline compounds bearing isolated ring-opened azetidine moiety.
Clinical records anonymisation and text extraction (CRATE): an open-source software system.
Cardinal, Rudolf N
2017-04-26
Electronic medical records contain information of value for research, but contain identifiable and often highly sensitive confidential information. Patient-identifiable information cannot in general be shared outside clinical care teams without explicit consent, but anonymisation/de-identification allows research uses of clinical data without explicit consent. This article presents CRATE (Clinical Records Anonymisation and Text Extraction), an open-source software system with separable functions: (1) it anonymises or de-identifies arbitrary relational databases, with sensitivity and precision similar to previous comparable systems; (2) it uses public secure cryptographic methods to map patient identifiers to research identifiers (pseudonyms); (3) it connects relational databases to external tools for natural language processing; (4) it provides a web front end for research and administrative functions; and (5) it supports a specific model through which patients may consent to be contacted about research. Creation and management of a research database from sensitive clinical records with secure pseudonym generation, full-text indexing, and a consent-to-contact process is possible and practical using entirely free and open-source software.
CJEP will offer open science badges.
Pexman, Penny M
2017-03-01
This editorial announces the decision of the Canadian Journal of Experimental Psychology (CJEP) to offer Open Science Framework (OSF) Badges. The Centre for Open Science provides tools to facilitate open science practices. These include the OSF badges. The badges acknowledge papers that meet standards for openness of data, methods, or research process. They are now described in the CJEP Submission Guidelines, and are provided in the editorial. (PsycINFO Database Record (c) 2017 APA, all rights reserved).
Yokota, Hajime; Goto, Mariko; Bamba, Chisa; Kiba, Maki; Yamada, Kei
2017-05-01
To assess whether alterations in the type of duty assignment system can affect the reading efficiency and stress level of diagnostic radiologists. Fourteen board-certified diagnostic radiologists were enrolled. We investigated three different reading systems for 1 week each. System 1 is our default, in which there are no assigned duties and everyone finishes when all cases are done. In system 2, two late shift readers are assigned every day, and, after everyone else leaves at a fixed time (5:30 p.m.), they take all remaining cases until they are finished. In system 3, a dedicated single reader is assigned to finish 30 cases, and everyone else will read all remaining cases. The total time required for reading and the number of cases read were recorded. In addition, participants completed two questionnaires regarding work-related stress. There was a trend toward shorter finishing time in system 2 and 3 compared to system 1 (P = 0.072 and 0.012). In terms of working stress, the subjective burden was lighter when systems 2 or 3 were employed. Minor modification of the duty assignment system has the potential to improve working efficiency and may reduce the work-related stress of diagnostic radiologists.
Kowalski, Alix; Huang, Yi Ting
2017-09-01
Relative-clause sentences (RCs) have been a key test case for psycholinguistic models of comprehension. While object-relative clauses (e.g., ORCs: "The bear that the horse . . .") are distinguished from subject-relative clauses (SRCs) after the second noun phrase (NP2; e.g., SRCs: "The bear that pushed . . ."), role assignments are often delayed until the embedded verb (e.g., ". . . pushed ate the sandwich"). This contrasts with overwhelming evidence of incremental role assignment in other garden-path sentences. The current study investigates how contextual factors modulate reliance on verbal and nonverbal cues. Using a visual-world paradigm, participants saw preceding discourse contexts that highlighted relevant roles within events (e.g., pusher, pushee). Nevertheless, role assignment for ORCs remained delayed until the embedded verb (Experiment 1). However, role assignment for ORCs occurred before the embedded verb when additional linguistic input was provided by an adverb (Experiment 2). Finally, when the likelihood of encountering RCs increased within the experimental context, role immediate assignment for ORCs was observed after NP2 (Experiment 3). Together, these findings suggest that real-time role assignment often prefers verbal cues, but can also flexibly adapt to the statistical properties of the local context. (PsycINFO Database Record (c) 2017 APA, all rights reserved).
Triage level assignment and nurse characteristics and experience.
Gómez-Angelats, Elisenda; Miró, Òscar; Bragulat Baur, Ernesto; Antolín Santaliestra, Alberto; Sánchez Sánchez, Miquel
2018-06-01
To study the relation between nursing staff demographics and experience and their assignment of triage level in the emergency department. One-year retrospective observational study in the triage area of a tertiary care urban university hospital that applies the Andorran-Spanish triage model. Variables studied were age, gender, nursing experience, triage experience, shift, usual level of emergency work the nurse undertakes, number of triage decisions made, and percentage of patients assigned to each level. Fifty nurses (5 men, 45 women) with a mean (SD) age of 45 (9) years triaged 67 803 patients during the year. Nurses classified more patients in level 5 on the morning shift (7.9%) than on the afternoon shift (5.5%) (P=.003). The difference in the rate of level-5 triage classification became significant when nurses were older (β = 0.092, P=.037) and experience was greater (β = 0.103, P=.017). The number of triages recorded by a nurse was significantly and directly related to the percentage of patients assigned to level 3 (β = 0.003, P=.006) and inversely related to the percentages assigned to level 4 (β = -0.002, P=.008) and level 5 (β = -0.001, P=.017). We found that triage level assignments were related to age, experience, shift, and total number of patients triaged by a nurse.
15 CFR 990.45 - Administrative record.
Code of Federal Regulations, 2011 CFR
2011-01-01
... decide to proceed with restoration planning, they must open a publicly available administrative record to... public comments; (2) Any relevant data, investigation reports, scientific studies, work plans, quality...
15 CFR 990.45 - Administrative record.
Code of Federal Regulations, 2010 CFR
2010-01-01
... decide to proceed with restoration planning, they must open a publicly available administrative record to... public comments; (2) Any relevant data, investigation reports, scientific studies, work plans, quality...
NASA Astrophysics Data System (ADS)
Hartman, K.; Dzulkifli, D. D. B.; Moynihan, M. A.; Salman, R.; Goodkin, N.
2017-12-01
267 undergraduate students in an interdisciplinary environmental sustainability course were divided into 66 groups for the duration of the semester. The formation of the groups proceeded by first assigning all of the science majors to groups in a random order. This was followed by assigning the engineering majors, the liberal arts majors, and finally the business majors in turn. After all of the students had been assigned to a group, every group had at least one engineering student and one science student. 11 groups had a liberal arts student but no business student. 26 groups had a business student but no liberal arts student. 29 groups were composed of students from all four majors. During the semester, the groups created an environmental action plan to address one of Singapore's major sustainability concerns: food. In service of the course's emphasis on interdisciplinary communication, the groups were required to create a video to support their environmental action plan. The evaluation method for the videos built on our prior work with rubrics (Hartman & Goodkin, 2016). While we provided a number of examples of videos communicating environmental action plans, students were not prescribed a particular format for their video. To the consternation of some students, the instructor deliberately left the video assessment open-ended. After the semester ended, a researcher coded all 66 videos for the food sustainability issues they identified, their proposed solutions, and their video approach. Approaches included animations, virtual handwriting/drawing, role-playing, PowerPoint presentations, and picture slideshows. Given the open-ended nature of the video project, we hypothesized that groups would converge on approaches that at least one team member was familiar with. We knew from prior work with the business school, that its students engage in role-play activities fairly frequently. Teams with a business major and without a liberal arts major adopted the role-play approach 23% of the time. Teams with both, exhibited the role-play approach 10% of the time. Teams without a business major did not exhibit the role-play approach. The differences in approach rates support the notion that students carry their repertoire of assessment practices with them to courses outside of their domain.
Minamisawa, T; Hirokaga, K
1995-11-01
The open-field activity of first-generation (F1) hybrid male C57BL/6 x C3H mice irradiated with gamma rays on day 14 of gestation was studied at the following ages: 6-7 months (young), 12-13 months (adult) and 19-20 months (old). Doses were 0.5 Gy or 1.0 Gy. Open-field activity was recorded with a camera. The camera output signal was recorded every second through an A/D converter to a personal computer. The field was divided into 25 8-cm2 units. All recordings were continuous for 60 min. The walking speed of the 1.0-Gy group recorded at 19-20 months was higher than that for the comparably aged control group. The time which the irradiated group, recorded at 19-20 months, spent in the corner fields was high in comparison with the control group at the same age. Conversely, the time spent by the irradiated group in the middle fields when recorded at 19-20 months was shorter than in the comparably aged control group. No effect of radiation was shown for any of the behaviors observed and recorded at 6-7 and 12-13 months. The results demonstrate that such exposure to gamma rays on day 14 of gestation results in behavioral changes which occur at 19-20 months but not at 6-7 or 12-13 months.
Egan, Cameron; Bernstein, Ethan; Reddy, Desigen; Ali, Madi; Paul, James; Yang, Dongsheng; Sessler, Daniel I
2011-11-01
The PerfecTemp is an underbody resistive warming system that combines servocontrolled underbody warming with viscoelastic foam pressure relief. Clinical efficacy of the system has yet to be formally evaluated. We therefore tested the hypothesis that intraoperative distal esophageal (core) temperatures with the PerfecTemp (underbody resistive) warming system are noninferior to upper-body forced-air warming in patients undergoing major open abdominal surgery under general anesthesia. Adults scheduled for elective major open abdominal surgery (liver, pancreas, gynecological, and colorectal surgery) under general anesthesia were enrolled at 2 centers. Patients were randomly assigned to underbody resistive or forced-air warming. Resistive heating started when patients were transferred to the operating room table; forced-air warming started after patients were draped. The primary outcome was noninferiority of intraoperative time-weighted average core temperature, adjusted for baseline characteristics and using a buffer of 0.5°C. Thirty-six patients were randomly assigned to underbody resistive heating and 34 to forced-air warming. Baseline and surgical characteristics were generally similar. We had sufficient evidence (P=0.018) to conclude that underbody resistive warming is not worse than (i.e., noninferior to) upper-body forced-air warming in the time-weighted average intraoperative temperature, with a mean difference of -0.12°C [95% confidence interval (CI) -0.37 to 0.14]. Core temperatures at the end of surgery averaged 36.3°C [95% CI 36 to 36.5] in the resistive warming patients and 36.6°C [95% CI 36.4 to 36.8] in those assigned to forced-air warming for a mean difference of -0.34°C [95% CI -0.69 to 0.01]. Mean intraoperative time-weighted average core temperatures were no different, and significantly noninferior, with underbody resistive heating in comparison with upper-body forced-air warming. Underbody resistive heating may be an alternative to forced-air warming.
NASA Astrophysics Data System (ADS)
Gifford, Fay Evan
The purpose of this study was to determine the difference in gender participation in the college physical science laboratory as perceived by students. The sample n this study consisted of 168 college sophomore architecture students (56 males and 33 females) and engineering students (61 males and 18 females). Depending on the type of information desired, a number of analyses were used including independent samples t-test, two-way Anova, general linear model analysis, Univariate analysis of variance, and descriptive statistics. In the analysis of data for the first fourteen questions of the questionnaire, which are called descriptive data, both gender and academic discipline differences were examined. It was found both genders picked personal choice as the role they played in the lab, and they were recorder, computer operator, and set up. There was no major difference here for the two disciplines except for engineers (by four to one over the architectures), who thought one member took the lead and assigned the role. There was no statistically significant difference in attitude toward group laboratory work between the two genders, but there was a significant difference by academic discipline here. There was a significant difference between genders for the way that students were assigned to small groups (i.e., the females would prefer the professor assign the role). For the open-ended student question dealing with suggestions for improving student participation in the labs, about one-third responded. One major difference between the disciplines was the architectural students by a twenty to one ratio over the engineers thought they didn't need a physics lab. For Hypothesis 4, there was a general agreement between the students' and the instructors' that there was not a difference in the students' gender responses and the instructors'. For Hypothesis 5, the responses from the four special gender questions for the students and instructors show that the males don't agree with the instructors on any of the four questions, but the females agree with the instructors on two of the questions.
The spectrum of rheumatic in-patient diagnoses at a pediatric hospital in Kenya.
Migowa, Angela; Colmegna, Inés; Hitchon, Carol; Were, Eugene; Ng'ang'a, Evelyn; Ngwiri, Thomas; Wachira, John; Bernatsky, Sasha; Scuccimarri, Rosie
2017-01-14
Pediatric rheumatic diseases are chronic illnesses that can cause considerable disease burden to children and their families. There is limited epidemiologic data on these diseases in East Africa. The aim of this study was to assess the spectrum of pediatric rheumatic diagnoses in an in-patient setting and determine the accuracy of ICD-10 codes in identifying these conditions. Medical records from Gertrude's Children's Hospital in Kenya were reviewed for patients diagnosed with "diseases of the musculoskeletal system and connective tissue" as per ICD-10 diagnostic codes assigned at discharge between January and December 2011. Cases were classified as "rheumatic" or "non-rheumatic". Accuracy of the assigned ICD-10 code was ascertained. Death records were reviewed. Longitudinal follow-up of "rheumatic" cases was done by chart review up to March 2014. Twenty six patients were classified as having a "rheumatic" condition accounting for 0.32% of patients admitted. Of these, 11 (42.3%) had an acute inflammatory arthropathy, 6 (23.1%) had septic arthritis, 4 (15.4%) had Kawasaki disease, 2 (7.7%) had pyomyositis, and there was one case each of septic bursitis, rheumatic fever, and a non-specific soft tissue disorder. No cases of juvenile idiopathic arthritis (JIA) were identified. One case of systemic lupus erythematosus was documented by death records. The agreement between the treating physician's discharge diagnosis and medical records ICD-10 code assignment was good (Kappa: 0.769). On follow-up, one child had recurrent knee swelling that was suspicious for JIA. Pediatric rheumatic conditions represented 0.32% of admissions at a pediatric hospital in Kenya. Acute inflammatory arthropathies, septic arthritis and Kawasaki disease were the most frequent in-patient rheumatic diagnoses. Chronic pediatric rheumatic diseases were rare amongst this in-patient population. Despite limitations associated with the use of administrative diagnostic codes, they can be a first step in evaluating the spectrum of pediatric rheumatic conditions in Kenya and other countries in East Africa.
Minamisawa, T; Hirokaga, K
1996-06-01
The open field activity of first generation (F1) hybrid male C57BL/6 x C3H mice irradiated with gamma-rays on the 14th day of gestation was studied at the following ages: 6-7 months, 12-13 months and 19-20 months. Doses were 0.1 Gy or 0.2 Gy. Open field activity was recorded with a camera. The camera output signal was recorded every sec through an A/D converter to a personal computer. The field was divided into 25 units of 8 cm square. All recordings were continuous for 60 min. The time which the 0.2-Gy group recorded at 6-7 months, spent in the 4 squares in the corner fields was high in comparison with the control group at the same age. The walking distance of the 0.1-Gy group recorded at 12-13 months was longer than that for the age matched control group. No effect of radiation was found on any of the behaviors observed and recorded at 19-20 months. The results demonstrate that exposure to low levels of gamma-rays on the 14th day of gestation results in behavioral changes, which occur at 6-7 and 12-13 months but not 19-20 months.
Strasser, Torsten; Peters, Tobias; Jägle, Herbert; Zrenner, Eberhart
2018-02-01
The ISCEV standards and recommendations for electrophysiological recordings in ophthalmology define a set of protocols with stimulus parameters, acquisition settings, and recording conditions, to unify the data and enable comparability of results across centers. Up to now, however, there are no standards to define the storage and exchange of such electrophysiological recordings. The aim of this study was to develop an open standard data format for the exchange and storage of visual electrophysiological data (ElVisML). We first surveyed existing data formats for biomedical signals and examined their suitability for electrophysiological data in ophthalmology. We then compared the suitability of text-based and binary formats, as well as encoding in Extensible Markup Language (XML) and character/comma-separated values. The results of the methodological consideration led to the development of ElVisML with an XML-encoded text-based format. This allows referential integrity, extensibility, the storing of accompanying units, as well as ensuring confidentiality and integrity of the data. A visualization of ElVisML documents (ElVisWeb) has additionally been developed, which facilitates the exchange of recordings on mailing lists and allows open access to data along with published articles. The open data format ElVisML ensures the quality, validity, and integrity of electrophysiological data transmission and storage as well as providing manufacturer-independent access and long-term archiving in a future-proof format. Standardization of the format of such neurophysiology data would promote the development of new techniques and open software for the use of neurophysiological data in both clinic and research.
NASA Astrophysics Data System (ADS)
Silva, S. R.; Kendall, C.; Young, M. B.; Choy, D.
2011-12-01
The USGS Isotope Tracers Project uses stable isotopes and tritium to add a unique dimension of chemical information to a wide range of environmental investigations. The use and application of isotopes is usually an unfamiliar and even esoteric topic to the general public. Therefore during three USGS open house events, as a public outreach effort, we demonstrated the use of stable isotopes by analyzing nitrogen and carbon isotopes from very small fragments of fingernail from willing participants. We titled the exhibit "You Are What You Eat". The results from all participants were plotted on a graph indicating the general influence of different food groups on the composition of body tissues as represented by fingernails. All participants were assigned a number and no personal-identification information was collected. A subset of participants provided us with an estimate of the number of days a week various foods were eaten and if they were vegetarians, vegans or non-vegetarians. Volunteers from our research group were on hand to explain and discuss fundamental concepts such as how foods attain their isotopic composition, the difference between C3 and C4 plants, the effects of assimilation, trophic enrichment, and the various uses of stable isotopes in environmental studies. The results of the fingernail analyses showed the variation of the range of isotopic compositions among about 400 people at each event, the distinct influence of C4 plants (mainly corn and cane sugar) on our carbon isotopic composition, and the isotopic differences between vegetarians and non vegetarians among other details (http://wwwrcamnl.wr.usgs.gov/isoig/projects/fingernails/). A poll of visitors attending the open house event in 2006 indicated that "You Are What You Eat" was among the most popular exhibits. Following the first two open house events we were contacted by a group of researchers from Brazil who had completed a very similar study. Our collaboration resulted in a publication in the American Journal of Physical Anthropology (Nardoto et al., 2006). This study found that despite global trends toward dietary homogenization, regional differences in food resources and dietary preferences were recorded in the carbon and nitrogen isotopic compositions of fingernails.
NASA Astrophysics Data System (ADS)
Montañez, Isabel P.; Osleger, Dillon J.; Chen, Jitao; Wortham, Barbara E.; Stamm, Robert G.; Nemyrovska, Tamara I.; Griffin, Julie M.; Poletaev, Vladislav I.; Wardlaw, Bruce R.
2018-06-01
Reconstructions of paleo-seawater chemistry are largely inferred from biogenic records of epicontinental seas. Recent studies provide considerable evidence for large-scale spatial and temporal variability in the environmental dynamics of these semi-restricted seas that leads to the decoupling of epicontinental isotopic records from those of the open ocean. We present conodont apatite δ18OPO4 and 87Sr/86Sr records spanning 24 Myr of the late Mississippian through Pennsylvanian derived from the U-Pb calibrated cyclothemic succession of the Donets Basin, eastern Ukraine. On a 2 to 6 Myr-scale, systematic fluctuations in bioapatite δ18OPO4 and 87Sr/86Sr broadly follow major shifts in the Donets onlap-offlap history and inferred regional climate, but are distinct from contemporaneous more open-water δ18OPO4 and global seawater Sr isotope trends. A -1 to -6‰ offset in Donets δ18OPO4 values from those of more open-water conodonts and greater temporal variability in δ18OPO4 and 87Sr/86Sr records are interpreted to primarily record climatically driven changes in local environmental processes in the Donets sea. Systematic isotopic shifts associated with Myr-scale sea-level fluctuations, however, indicate an extrabasinal driver. We propose a mechanistic link to glacioeustasy through a teleconnection between high-latitude ice changes and atmospheric pCO2 and regional monsoonal circulation in the Donets region. Inferred large-magnitude changes in Donets seawater salinity and temperature, not archived in the more open-water or global contemporaneous records, indicate a modification of the global climate signal in the epicontinental sea through amplification or dampening of the climate signal by local and regional environmental processes. This finding of global climate change filtered through local processes has implications for the use of conodont δ18OPO4 and 87Sr/86Sr values as proxies of paleo-seawater composition, mean temperature, and glacioeustasy.
Montanez, Isabel P.; Osleger, Dillon J.; Chen, J.-H.; Wortham, Barbara E.; Stamm, Robert G.; Nemyrovska, Tamara I.; Griffin, Julie M.; Poletaev, Vladislav I.; Wardlaw, Bruce R.
2018-01-01
Reconstructions of paleo-seawater chemistry are largely inferred from biogenic records of epicontinental seas. Recent studies provide considerable evidence for large-scale spatial and temporal variability in the environmental dynamics of these semi-restricted seas that leads to the decoupling of epicontinental isotopic records from those of the open ocean. We present conodont apatite δ18OPO4 and 87Sr/86Sr records spanning 24 Myr of the late Mississippian through Pennsylvanian derived from the U–Pb calibrated cyclothemic succession of the Donets Basin, eastern Ukraine. On a 2 to 6 Myr-scale, systematic fluctuations in bioapatite δ18OPO4 and 87Sr/86Sr broadly follow major shifts in the Donets onlap–offlap history and inferred regional climate, but are distinct from contemporaneous more open-water δ18OPO4 and global seawater Sr isotope trends. A −1 to −6‰ offset in Donets δ18OPO4 values from those of more open-water conodonts and greater temporal variability in δ18OPO4 and 87Sr/86Sr records are interpreted to primarily record climatically driven changes in local environmental processes in the Donets sea. Systematic isotopic shifts associated with Myr-scale sea-level fluctuations, however, indicate an extrabasinal driver. We propose a mechanistic link to glacioeustasy through a teleconnection between high-latitude ice changes and atmospheric pCO2 and regional monsoonal circulation in the Donets region. Inferred large-magnitude changes in Donets seawater salinity and temperature, not archived in the more open-water or global contemporaneous records, indicate a modification of the global climate signal in the epicontinental sea through amplification or dampening of the climate signal by local and regional environmental processes. This finding of global climate change filtered through local processes has implications for the use of conodont δ18OPO4 and 87Sr/86Sr values as proxies of paleo-seawater composition, mean temperature, and glacioeustasy.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT EDUCATION... designee shall assign to an education staff member the responsibility to coordinate the institution's ESL... ESL Program Record, and shall place it in the inmate's education file. (d) Ordinarily, there will be...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-11
... and Research (PD&R) and its contractors to conduct a random assignment and impact evaluation study of... ``Purpose'' section to obtain detailed information about the purpose of this study. DATES: Effective Date...
Maeda-Yamamoto, Mari; Ema, Kaori; Monobe, Manami; Shibuichi, Ikuo; Shinoda, Yuki; Yamamoto, Tomohiro; Fujisawa, Takao
2009-09-01
We previously reported that 'benifuuki' green tea containing O-methylated catechin significantly relieved the symptoms of perennial or seasonal rhinitis compared with a placebo green tea that did not contain O-methylated catechin in randomized double-blind clinical trials. In this study we assessed the effects of 'benifuuki' green tea on clinical symptoms of seasonal allergic rhinitis. An open-label, single-dose, randomized, parallel-group study was performed on 38 subjects with Japanese cedar pollinosis. The subjects were randomly assigned to long-term (December 27, 2006-April 8, 2007, 1.5 months before pollen exposure) or short-term (February 15, 2007: after cedar pollen dispersal--April 8, 2007) drinking of a 'benifuuki' tea drink containing 34 mg O-methylated catechin per day. Each subject recorded their daily symptom scores in a diary. The primary efficacy variable was the mean weekly nasal symptom medication score during the study period. The nasal symptom medication score in the long-term intake group was significantly lower than that of the short-term intake group at the peak of pollen dispersal. The symptom scores for throat pain, nose-blowing, tears, and hindrance to activities of daily living were significantly better in the long-term group than the short-term group. In particular, the differences in the symptom scores for throat pain and nose-blowing between the 2 groups were marked. We conclude that drinking 'benifuuki' tea for 1.5 months prior to the cedar pollen season is effective in reducing symptom scores for Japanese cedar pollinosis.
Tectonic implications of facies patterns, Lower Permian Dry Mountain trough, east-central Nevada
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gallegos, D.M.; Snyder, W.S.; Spinosa, C.
1991-02-01
Paleozoic tectonism is indicated by a study of a west-east facies analysis transect across the northern portion of the Lower Permian Dry Mountain trough (DMT). In an attempt to characterize the Early Permian basin-filling sequences, three broadly recognizable facies packages have been identified across the DMT: the western margin facies and the central basin facies of the DMT and an eastern shelf facies. In the western margin facies of the basin, pulses of tectonic activity are recorded at McCloud Spring in the Sulphur Springs Range. Here, shallow open-marine carbonate overlies eroded Vinini Formation and, in turn, is unconformably overlain bymore » basinal marine carbonate. An unconformity also marks the contact with the overriding prograding coarse clastic facies. These abrupt transitions suggest the sediments were deposited in a tectonically active area where they preservation of Waltherian sequences is unlikely to occur. Similarly abrupt transitions are evident in the western part of the central basin facies. At Portuguese Springs n the Diamond Range, a thin basal marine conglomerate delineates Lower Permian sedimentation over the Pennsylvanian Ely Formation. Coarsening-upward basinal carbonate strata of pelagic, hemipelagic, and turbidite components overlie the basal conglomerate. this progression of sediments is unconformably overlain by a subaerial sequence of coarse clastic deposits. Within the eastern part of the central basin facies in the Maverick Spring Range, the Lower Permian sediments are open-marine siltstone, wackestone, packstone, and grainstone. The sediments are assigned to a gradually sloping ramp, indicating the effects of tectonism on this margin of the basin were subdued.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lloyd, R.D.; Gren, D.C.; Simon, S.L.
External gamma-ray exposures from fallout originating at the Nevada Test Site (NTS) have been assigned to 6,507 individual subjects (1,177 leukemia cases and 5,330 control subjects) who died as Utah residents between 1952 and 1981. Leukemia cases were identified, confirmed, and classified by cell type from the Utah Cancer Registry, Utah State vital records, and medical records. Residential histories were obtained from the Deceased Membership File (DMF) of the Church of Jesus Christ of Latter-day Saints (LDS), supplemented by information from the LDS Church Census Records that were taken in 1950, 1955, and 1960-62. Control subjects were selected randomly withinmore » age strata from the DMF and were frequency-matched to the cases by age at death and for sex. Individual radiation exposures were assigned as a function of residence location and time interval for each residence during the fallout period (1951-1958) using geographic exposure data taken from the literature. Temporal distribution of exposure for subjects who resided in more than one locality or who were born or died during the fallout period was determined from data of other investigators. Calculated gamma-ray exposures for each place of residence were summed for each subject to yield the exposure to fallout from the NTS.« less
Zafirah, S A; Nur, Amrizal Muhammad; Puteh, Sharifa Ezat Wan; Aljunid, Syed Mohamed
2018-01-25
The accuracy of clinical coding is crucial in the assignment of Diagnosis Related Groups (DRGs) codes, especially if the hospital is using Casemix System as a tool for resource allocations and efficiency monitoring. The aim of this study was to estimate the potential loss of income due to an error in clinical coding during the implementation of the Malaysia Diagnosis Related Group (MY-DRG ® ) Casemix System in a teaching hospital in Malaysia. Four hundred and sixty-four (464) coded medical records were selected, re-examined and re-coded by an independent senior coder (ISC). This ISC re-examined and re-coded the error code that was originally entered by the hospital coders. The pre- and post-coding results were compared, and if there was any disagreement, the codes by the ISC were considered the accurate codes. The cases were then re-grouped using a MY-DRG ® grouper to assess and compare the changes in the DRG assignment and the hospital tariff assignment. The outcomes were then verified by a casemix expert. Coding errors were found in 89.4% (415/424) of the selected patient medical records. Coding errors in secondary diagnoses were the highest, at 81.3% (377/464), followed by secondary procedures at 58.2% (270/464), principal procedures of 50.9% (236/464) and primary diagnoses at 49.8% (231/464), respectively. The coding errors resulted in the assignment of different MY-DRG ® codes in 74.0% (307/415) of the cases. From this result, 52.1% (160/307) of the cases had a lower assigned hospital tariff. In total, the potential loss of income due to changes in the assignment of the MY-DRG ® code was RM654,303.91. The quality of coding is a crucial aspect in implementing casemix systems. Intensive re-training and the close monitoring of coder performance in the hospital should be performed to prevent the potential loss of hospital income.
Lei, Yanlin; Sun, Ninglei; Wilson, Fraser A W; Wang, Xiusong; Chen, Nanhui; Yang, Jianzhen; Peng, Yanping; Wang, Jianhong; Tian, Shaohua; Wang, Maohua; Miao, Yingda; Zhu, Weina; Qi, Hua; Ma, Yuanye
2004-05-30
This paper describes a portable recording system and methods for obtaining chronic recordings of single units and tracking rhesus monkey behavior in an open field. The integrated system consists of four major components: (1) microelectrode assembly; (2) head-stage; (3) recording station; and (4) data storage station, the first three of which are carried by the monkey and weigh 800 g. Our system provides synchronized video and electrophysiological signals, which are transmitted by a wireless system to a distance of 50 m. Its major advantages are that neuronal recordings are made in freely moving monkeys, and well-separated action potentials with amplitude five times higher than the background noise are usually recorded and readily kept for many hours. Using this system, we were able to study "place cells" in non-human primate brains. The described methods provide a new way to examine correlations between single neuron activity and primate behaviors, and can also be used to study the cellular basis of social behaviors in non-human primates.
Documenting death: public access to government death records and attendant privacy concerns.
Boles, Jeffrey R
2012-01-01
This Article examines the contentious relationship between public rights to access government-held death records and privacy rights concerning the deceased, whose personal information is contained in those same records. This right of access dispute implicates core democratic principles and public policy interests. Open access to death records, such as death certificates and autopsy reports, serves the public interest by shedding light on government agency performance, uncovering potential government wrongdoing, providing data on public health trends, and aiding those investigating family history, for instance. Families of the deceased have challenged the release of these records on privacy grounds, as the records may contain sensitive and embarrassing information about the deceased. Legislatures and the courts addressing this dispute have collectively struggled to reconcile the competing open access and privacy principles. The Article demonstrates how a substantial portion of the resulting law in this area is haphazardly formed, significantly overbroad, and loaded with unintended consequences. The Article offers legal reforms to bring consistency and coherence to this currently disordered area of jurisprudence.
The effect of background music on the perception of personality and demographics.
Lastinger, Daniel L
2011-01-01
This study seeks to discover stereotypes people may have about different music genres and if these stereotypes are projected onto an individual. Also, the study investigates if music therapy students are more or less biased than non-music majors in this regard. Subjects (N=388) were comprised of student members of the American Music Therapy Association (N=182) and students from a college in the southeastern United States who were not music majors (N=206). Subjects were asked to listen to a recording and complete a short survey. Subjects assigned to the control condition heard only a person reading a script. Subjects assigned to one of the four experimental conditions heard the same recording mixed with background music and ambient crowd noise, intended to simulate a live performance. Subjects were asked to rate the person in the recording on personality descriptors and predict demographic information in the survey. Many of the survey responses were significantly affected by the genre of music. For example, it was shown that when in the presence of rap or country music, all subjects rated the personality of the person in the recording significantly more negative than when in the presence of classical, jazz, or no music. There were no significant differences between the groups for any variable or condition when comparing survey responses between college students and AMTA student members.
Utilization of open source electronic health record around the world: A systematic review.
Aminpour, Farzaneh; Sadoughi, Farahnaz; Ahamdi, Maryam
2014-01-01
Many projects on developing Electronic Health Record (EHR) systems have been carried out in many countries. The current study was conducted to review the published data on the utilization of open source EHR systems in different countries all over the world. Using free text and keyword search techniques, six bibliographic databases were searched for related articles. The identified papers were screened and reviewed during a string of stages for the irrelevancy and validity. The findings showed that open source EHRs have been wildly used by source limited regions in all continents, especially in Sub-Saharan Africa and South America. It would create opportunities to improve national healthcare level especially in developing countries with minimal financial resources. Open source technology is a solution to overcome the problems of high-costs and inflexibility associated with the proprietary health information systems.
Using OpenEHR in SICTI an electronic health record system for critical medicine
NASA Astrophysics Data System (ADS)
Filgueira, R.; Odriazola, A.; Simini, F.
2007-11-01
SICTI is a software tool for registering health records in critical medicine environments. Version 1.0 has been in use since 2003. The Biomedical Engineering Group (Núcleo de Ingeniería Biomédica), with support from the Technological Development Programme (Programa de Desarrollo Tecnológico), decided to develop a new version, to provide an aid for more critical medicine processes, based on a framework which would make the application domain change oriented. The team analyzed three alternatives: to develop an original product based on new research, to base the development on OpenEHR framework, or to use HL7 RIM as the reference model for SICTI. The team opted for OpenEHR. This work describes the use of OpenEHR, its strong and weak points, and states future work perspectives.
Amino acid selective unlabeling for sequence specific resonance assignments in proteins
Krishnarjuna, B.; Jaipuria, Garima; Thakur, Anushikha
2010-01-01
Sequence specific resonance assignment constitutes an important step towards high-resolution structure determination of proteins by NMR and is aided by selective identification and assignment of amino acid types. The traditional approach to selective labeling yields only the chemical shifts of the particular amino acid being selected and does not help in establishing a link between adjacent residues along the polypeptide chain, which is important for sequential assignments. An alternative approach is the method of amino acid selective ‘unlabeling’ or reverse labeling, which involves selective unlabeling of specific amino acid types against a uniformly 13C/15N labeled background. Based on this method, we present a novel approach for sequential assignments in proteins. The method involves a new NMR experiment named, {12COi–15Ni+1}-filtered HSQC, which aids in linking the 1HN/15N resonances of the selectively unlabeled residue, i, and its C-terminal neighbor, i + 1, in HN-detected double and triple resonance spectra. This leads to the assignment of a tri-peptide segment from the knowledge of the amino acid types of residues: i − 1, i and i + 1, thereby speeding up the sequential assignment process. The method has the advantage of being relatively inexpensive, applicable to 2H labeled protein and can be coupled with cell-free synthesis and/or automated assignment approaches. A detailed survey involving unlabeling of different amino acid types individually or in pairs reveals that the proposed approach is also robust to misincorporation of 14N at undesired sites. Taken together, this study represents the first application of selective unlabeling for sequence specific resonance assignments and opens up new avenues to using this methodology in protein structural studies. Electronic supplementary material The online version of this article (doi:10.1007/s10858-010-9459-z) contains supplementary material, which is available to authorized users. PMID:21153044
Johnston, Charlotte; Weiss, Margaret; Murray, Candice; Miller, Natalie
2011-11-01
We examined whether instructional materials describing how to rate child ADHD symptoms would improve the accuracy of mothers' ratings of ADHD symptoms presented in standard child behavior stimuli, and whether instructions would be equally effective across a range of maternal depressive symptoms and family incomes. A community sample of 100 mothers with 5 to 12 year old sons were randomly assigned to either receive or not receive the instructions. All mothers watched standard video recordings of boys displaying nonproblem behavior, ADHD symptoms, ADHD plus oppositional behaviors, or ADHD plus anxious behaviors, and then rated the ADHD symptoms of the boys in the videos. These ratings were compared to ratings of the boys' ADHD symptoms made by objective coders. Results indicated an interaction such that the instructional materials improved the agreement between mothers' and coders' ratings, but only for mothers at lower family income levels. The instructional materials improved all mothers' open-ended responses regarding knowledge of ADHD. All mothers rated more ADHD symptoms in boys with comorbid oppositional or anxious behaviors, and this effect was not reduced by the instructional materials. The potential utility of these instructions to improve the accuracy of ratings of child ADHD symptoms is explored.
Process of Argumentation in High School Biology Class: A Qualitative Analysis
NASA Astrophysics Data System (ADS)
Ramli, M.; Rakhmawati, E.; Hendarto, P.; Winarni
2017-02-01
Argumentation skill can be nurtured by designing a lesson in which students are provided with the opportunity to argue. This research aims to analyse argumentation process in biology class. The participants were students of three biology classes from different high schools in Surakarta Indonesia. One of the classroom was taught by a student teacher, and the rest were instructed by the assigned teachers. Through a classroom observation, oral activities were noted, audio-recorded and video-taped. Coding was done based on the existence of claiming-reasoning-evidence (CRE) process by McNeill and Krajcik. Data was analysed qualitatively focusing on the role of teachers to initiate questioning to support argumentation process. The lesson design of three were also analysed. The result shows that pedagogical skill of teachers to support argumentation process, such as skill to ask, answer, and respond to students’ question and statements need to be trained intensively. Most of the argumentation found were only claiming, without reasoning and evidence. Teachers have to change the routine of mostly posing open-ended questions to students, and giving directly a correct answer to students’ questions. Knowledge and skills to encourage student to follow inquiry-based learning have to be acquired by teachers.
NASA Astrophysics Data System (ADS)
Whittington, A. G.; Speck, A.; Witzig, S.
2011-12-01
As part of an NSF-funded project, "CUES: Connecting Undergraduates to the Enterprise of Science," new inquiry-based homework materials were developed for two upper-level classes at the University of Missouri: Geochemistry (required for Geology majors, fulfills the computing requirement by having 50% of the grade come from five spreadsheet-based homework assignments), and Solar System Science (open to seniors and graduate students, co-taught and cross-listed between Geology and Physics & Astronomy). Inquiry involves activities where the learner engages in scientifically oriented questions, gives priority to evidence in responding to questions, formulates explanations from evidence, connects explanations to scientific knowledge, and communicates and justifies explanations. We engage students in inquiry-based learning by presenting homework exercises as "mini-journal" articles that follow the format of a scientific journal article, including a title, authors, abstract, introduction, methods, results, discussion and citations to peer-reviewed literature. The mini-journal provides a scaffold and serves as a springboard for students to develop and carry out their own follow-up investigation. They then present their findings in the form of their own mini-journal. Mini-journals replace traditional homework problem sets with a format that more directly reflects and encourages scientific practice. Students are engaged in inquiry-based homework which encompass doing, thinking, and communicating, while the mini-journal allows the instructor to contain lines of inquiry within the limits posed by available resources. In the examples we present, research is conducted via spreadsheet modeling, where the students develop their own spreadsheets. Example assignments from Geochemistry include "Trace Element Partitioning During Mantle Melting and MORB Crystallization" and "Isotopic Investigations of Crustal Evolution in the Midcontinent US". The key differences between the old and new formats include (i) active participation of the students in defining the question/problem that they will pursue, within well-defined boundaries, (ii) open-ended nature of the inquiry, so that students need to recognize when they have enough information to answer their question, (iii) extensive spreadsheet manipulation and presentation of results in graphical and tabular formats, and (iv) a written discussion of their findings. Grading is weighted more towards how the problem was addressed, and how findings are presented and interpreted, and less on actual numerical answers. Survey responses from students indicate that they experience discomfort on being presented with an open-ended assignment, but like the freedom to define their own problem. Students also recognize that reading, writing and critical thinking skills employed in the minijournal format increase their understanding of content. The combination of calculation and writing components make these assignments particularly useful for classes designated as "computer-based", and/or "writing intensive" (or similar designations).
Difference in postural control between patients with functional and mechanical ankle instability.
Chen, Henry; Li, Hong-Yun; Zhang, Jian; Hua, Ying-Hui; Chen, Shi-Yi
2014-10-01
Lateral ankle sprain is one of the most common injuries. Since the structural and pathological differences in mechanical ankle instability (MAI) and functional ankle instability (FAI) may not be the same, it may be better to treat these as separate groups. The purpose of this study was to compare the difference in postural sway between MAI and FAI in patients with chronic ankle instability (CAI). Twenty-six patients with CAI and 14 healthy control participants were included in the study. The CAI patients were subdivided into MAI (15 patients) and FAI (11 patients) groups. Patients who were diagnosed with lateral ankle ligaments rupture by magnetic resonance imaging and ultrasonography were assigned to the MAI group. All participants performed single-limb postural sway tests 3 times on each leg with eyes closed and open. The average distances from the mean center of pressure position in the mediolateral and anteroposterior directions were recorded and compared among the 3 groups. The unstable ankles in the MAI group showed significantly greater postural sway in the anterior, posterior, and medial directions compared with those in the control group with eyes closed. With eyes open, significantly greater postural sway was found in the anterior direction. In the FAI group, no difference was found in postural sway compared with those in the control group. The MAI group showed significantly greater postural sway in the anterior direction compared with the FAI group with eyes closed and open. No significant difference in postural sway was found between the unstable and stable ankles in the MAI or FAI groups, with or without vision. Patients with MAI have deficits in postural control, especially in anterior-posterior directions. However, no difference was found in postural sway in patients with FAI compared with healthy people. As MAI patients suffer from deficits in postural control, balance training should be applied in those patients. In addition, special training should also include the contralateral side after a unilateral ankle ligament injured. © The Author(s) 2014.
Telfer, Emily J; Stovold, Grahame T; Li, Yongjun; Silva-Junior, Orzenil B; Grattapaglia, Dario G; Dungey, Heidi S
2015-01-01
Pedigree reconstruction using molecular markers enables efficient management of inbreeding in open-pollinated breeding strategies, replacing expensive and time-consuming controlled pollination. This is particularly useful in preferentially outcrossed, insect pollinated Eucalypts known to suffer considerable inbreeding depression from related matings. A single nucleotide polymorphism (SNP) marker panel consisting of 106 markers was selected for pedigree reconstruction from the recently developed high-density Eucalyptus Infinium SNP chip (EuCHIP60K). The performance of this SNP panel for pedigree reconstruction in open-pollinated progenies of two Eucalyptus nitens seed orchards was compared with that of two microsatellite panels with 13 and 16 markers respectively. The SNP marker panel out-performed one of the microsatellite panels in the resolution power to reconstruct pedigrees and out-performed both panels with respect to data quality. Parentage of all but one offspring in each clonal seed orchard was correctly matched to the expected seed parent using the SNP marker panel, whereas parentage assignment to less than a third of the expected seed parents were supported using the 13-microsatellite panel. The 16-microsatellite panel supported all but one of the recorded seed parents, one better than the SNP panel, although there was still a considerable level of missing and inconsistent data. SNP marker data was considerably superior to microsatellite data in accuracy, reproducibility and robustness. Although microsatellites and SNPs data provide equivalent resolution for pedigree reconstruction, microsatellite analysis requires more time and experience to deal with the uncertainties of allele calling and faces challenges for data transferability across labs and over time. While microsatellite analysis will continue to be useful for some breeding tasks due to the high information content, existing infrastructure and low operating costs, the multi-species SNP resource available with the EuCHIP60k, opens a whole new array of opportunities for high-throughput, genome-wide or targeted genotyping in species of Eucalyptus.
Teixeira, Miriam S.; Banks, Juliane; Swarts, J. Douglas; Alper, Cuneyt M.; Doyle, William J.
2014-01-01
Objective Test the hypothesis that active Eustachian tube opening efficiency as measured by sonotubometry is higher in adults with no extant middle-ear disease and no history of previous otitis media (Group-1) when compared to adults with no middle-ear disease but a positive history for otitis media (Group-2). Methods Eustachian tube function for 1 ear of 33 otherwise healthy adult subjects, 16 assigned to Group-1 and 17 to Group-2, was tested by sonotubometry using a standard protocol. For each test, the sound envelopes for 3 swallows were abstracted independently by 2 observers from the data stream and 7 descriptive parameters related to sound envelope “shape” were calculated. Interrelatedness among the values for the parameters was explored using correlation analysis. The contributions of swallow, observer and group to the variance in each parameter were evaluated for significance using a General Linear Model. Results The shape parameters reflecting envelope height, area and rise and fall rates were highly inter-correlated, but those reflecting envelope widths were not. There was no effect of “swallow” on any of the parameters; but there was a significant “observer” effect on all measures of envelope width, greater for observer-2, and a significant “group” effect for 5 of the 7 shape parameters, all greater in Group-1. Conclusions Quantifiable measures of the sound signal “shape” recorded by sonotubometry during swallowing were significantly different between the 2 groups of subjects. This is interpretable as evidencing a more efficient Eustachian tube opening-function in adults with healthy middle ears who do not have a previous history of otitis media when compared to similar adults with a history of prior otitis media. Inefficient Eustachian tube function as children may not be completely resolved by adulthood increasing adult otitis media risk when Eustachian tube function is down-graded by extant upper respiratory diseases that provoke nasopharyngeal inflammation. PMID:24491807
ERIC Educational Resources Information Center
Krystyniak, Rebecca A.; Heikkinen, Henry W.
2007-01-01
This study explores effects of participation by second-semester college general chemistry students in an extended, open-inquiry laboratory investigation. Verbal interactions among a student lab team and with their instructor over three open-inquiry laboratory sessions and two non-inquiry sessions were recorded, transcribed, and analyzed. Coding…
M2Lite: An Open-source, Light-weight, Pluggable and Fast Proteome Discoverer MSF to mzIdentML Tool.
Aiyetan, Paul; Zhang, Bai; Chen, Lily; Zhang, Zhen; Zhang, Hui
2014-04-28
Proteome Discoverer is one of many tools used for protein database search and peptide to spectrum assignment in mass spectrometry-based proteomics. However, the inadequacy of conversion tools makes it challenging to compare and integrate its results to those of other analytical tools. Here we present M2Lite, an open-source, light-weight, easily pluggable and fast conversion tool. M2Lite converts proteome discoverer derived MSF files to the proteomics community defined standard - the mzIdentML file format. M2Lite's source code is available as open-source at https://bitbucket.org/paiyetan/m2lite/src and its compiled binaries and documentation can be freely downloaded at https://bitbucket.org/paiyetan/m2lite/downloads.
Case Study: What Supports Students to Improve Their Grades?
ERIC Educational Resources Information Center
Sieminski, Sandy; Messenger, Julie; Murphy, Sam
2016-01-01
This case study considers students who achieved "borderline" (40-45%) grades in their first assignment on a module, but went on to markedly improve their grades over the course of the module. The students were studying nursing and social work at the UK Open University, and they were all sponsored by employers. Semi-structured telephone…
Supportive Training for Inexperienced and New Teachers (STINT). Part I.
ERIC Educational Resources Information Center
Fox, David J.; And Others
This document is an evaluative description of the program conducted by the New York City Board of Education during the 1968-69 school year. Opening chapters describe the two-phase evaluation design (descriptive and qualitative) and outline the program in which an initial group of 152 master teachers plus 100 more added in Febraury were assigned as…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-11-03
...-deployment/reintegration of women. Finally, to receive a briefing from the Defense Task Force on Sexual Assault in the Military. The meeting is open to the public, subject to the availability of space. DATES... Task Force on Sexual Assault in the Military Services --Services SME briefs on assignment and well...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-09
...) System Event Messages (e.g., start of messages, start of system hours, start of quoting, start of opening... assignments, to take advantage of the proposed $500 cap and thereby limit costs. \\11\\ Typically, a smaller... of the Exchange that is typically a small proprietary market maker doing business on the Exchange's...
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 2 2012-10-01 2012-10-01 false Air pipes. 42.15-50 Section 42.15-50 Shipping COAST... Conditions of Assignment of Freeboard § 42.15-50 Air pipes. (a) Where air pipes to ballast and other tanks.... Satisfactory means permanently attached, shall be provided for closing the openings of the air pipes. [CGFR 68...
Code of Federal Regulations, 2014 CFR
2014-10-01
... 46 Shipping 2 2014-10-01 2014-10-01 false Air pipes. 42.15-50 Section 42.15-50 Shipping COAST... Conditions of Assignment of Freeboard § 42.15-50 Air pipes. (a) Where air pipes to ballast and other tanks.... Satisfactory means permanently attached, shall be provided for closing the openings of the air pipes. [CGFR 68...
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 2 2013-10-01 2013-10-01 false Air pipes. 42.15-50 Section 42.15-50 Shipping COAST... Conditions of Assignment of Freeboard § 42.15-50 Air pipes. (a) Where air pipes to ballast and other tanks.... Satisfactory means permanently attached, shall be provided for closing the openings of the air pipes. [CGFR 68...
Library Information Made to Order: An Open Source Project Built for and with Librarians
ERIC Educational Resources Information Center
Griggs, Kim
2009-01-01
Oregon State University (OSU) libraries, where the author serves as lead programmer, have developed a tool to make it easier for librarians to build and maintain interactive course assignment pages (ICAPs) and subject research guides (SRGs). That tool, Library a la Carte, enables librarians with minimal technical expertise to create dynamic…
Ready or Not Repeal of Don’t Ask, Don’t Tell
2010-02-17
the DoD with enough power and vision to lead the change, The key was the Code avoided dealing with attitudes and beliefs, which are often...Additionally, in Israel, rather than alter facilities, “gay soldiers are assigned to open bases, allowing them to commute to and from home and sleep at
46 CFR 42.15-80 - Special conditions of assignment for Type “A” vessels.
Code of Federal Regulations, 2012 CFR
2012-10-01
... exposed if there are no openings giving direct access from the freeboard deck to the machinery space. A... a space or passageway which is as strongly constructed as the casing and is separated from the... accommodations and the machinery space. (c) Hatchways. Exposed hatchways on the freeboard and forecastle decks or...
46 CFR 42.15-80 - Special conditions of assignment for Type “A” vessels.
Code of Federal Regulations, 2014 CFR
2014-10-01
... exposed if there are no openings giving direct access from the freeboard deck to the machinery space. A... a space or passageway which is as strongly constructed as the casing and is separated from the... accommodations and the machinery space. (c) Hatchways. Exposed hatchways on the freeboard and forecastle decks or...
46 CFR 42.15-80 - Special conditions of assignment for Type “A” vessels.
Code of Federal Regulations, 2010 CFR
2010-10-01
... exposed if there are no openings giving direct access from the freeboard deck to the machinery space. A... a space or passageway which is as strongly constructed as the casing and is separated from the... accommodations and the machinery space. (c) Hatchways. Exposed hatchways on the freeboard and forecastle decks or...
46 CFR 42.15-80 - Special conditions of assignment for Type “A” vessels.
Code of Federal Regulations, 2013 CFR
2013-10-01
... exposed if there are no openings giving direct access from the freeboard deck to the machinery space. A... a space or passageway which is as strongly constructed as the casing and is separated from the... accommodations and the machinery space. (c) Hatchways. Exposed hatchways on the freeboard and forecastle decks or...
46 CFR 42.15-80 - Special conditions of assignment for Type “A” vessels.
Code of Federal Regulations, 2011 CFR
2011-10-01
... exposed if there are no openings giving direct access from the freeboard deck to the machinery space. A... a space or passageway which is as strongly constructed as the casing and is separated from the... accommodations and the machinery space. (c) Hatchways. Exposed hatchways on the freeboard and forecastle decks or...
Convenience or Credibility? A Study of College Student Online Research Behaviors
ERIC Educational Resources Information Center
Biddix, J. Patrick; Chung, Chung Joo; Park, Han Woo
2011-01-01
The purpose of this study was to investigate where students turn for course-related assignments, whether an ordered pattern could be described in terms of which sources students turn to and how students evaluated the information they chose to use. Data were drawn from open-ended questionnaires (n = 282). Semantic network analysis was conducted…
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 2 2010-10-01 2010-10-01 false Air pipes. 42.15-50 Section 42.15-50 Shipping COAST... Conditions of Assignment of Freeboard § 42.15-50 Air pipes. (a) Where air pipes to ballast and other tanks.... Satisfactory means permanently attached, shall be provided for closing the openings of the air pipes. [CGFR 68...
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 2 2011-10-01 2011-10-01 false Air pipes. 42.15-50 Section 42.15-50 Shipping COAST... Conditions of Assignment of Freeboard § 42.15-50 Air pipes. (a) Where air pipes to ballast and other tanks.... Satisfactory means permanently attached, shall be provided for closing the openings of the air pipes. [CGFR 68...
2012-03-01
Targeting Review Board OPLAN Operations Plan OPORD Operations Order OPSIT Operational Situation OSINT Open Source Intelligence OV...Analysis Evaluate FLTREPs MISREPs Unit Assign Assets Feedback Asset Shortfalls Multi-Int Collection Political & Embasy Law Enforcement HUMINT OSINT ...Embassy Information OSINT Manage Theater HUMINT Law Enforcement Collection Sort Requests Platform Information Agency Information M-I Collect
An Open Source Agenda for Research Linking Text and Image Content Features.
ERIC Educational Resources Information Center
Goodrum, Abby A.; Rorvig, Mark E.; Jeong, Ki-Tai; Suresh, Chitturi
2001-01-01
Proposes methods to utilize image primitives to support term assignment for image classification. Proposes to release code for image analysis in a common tool set for other researchers to use. Of particular focus is the expansion of work by researchers in image indexing to include image content-based feature extraction capabilities in their work.…
A Fuzzy Group Decision Making Model for Ordinal Peer Assessment
ERIC Educational Resources Information Center
Capuano, Nicola; Loia, Vincenzo; Orciuoli, Francesco
2017-01-01
Massive Open Online Courses (MOOCs) are becoming an increasingly popular choice for education but, to reach their full extent, they require the resolution of new issues like assessing students at scale. A feasible approach to tackle this problem is peer assessment, in which students also play the role of assessor for assignments submitted by…
Investigating Criteria That Seventh Graders Use to Evaluate the Quality of Online Information
ERIC Educational Resources Information Center
Coiro, Julie; Coscarelli, Carla; Maykel, Cheryl; Forzani, Elena
2015-01-01
This article presents qualitative findings from a study that examined the types of criteria that middle school students use to evaluate the quality of online information and sources for a Web-based research assignment. Open-constructed responses from four critical evaluation items were compiled from diverse seventh graders in a representative,…
6th, 7th and 8th Graders' Attitudes towards Online Homework Assignment Sites
ERIC Educational Resources Information Center
Altun, Eralp
2008-01-01
This study has pedagogical implications in view of rapidly growing technological development and widespread use of the Internet in instruction. The spread of online homework sites with highly commercial aims has opened a new research area regarding the structure, aim and the significant role of homework in education. Particularly, the changes in…
ERIC Educational Resources Information Center
Ezra, Elishai; Nahmias, Yaakov
2015-01-01
The advent of integrated multidisciplinary research has given rise to some of the most important breakthroughs of our time, but has also set significant challenges to the current educational paradigm. Current academic education often limits cross-discipline discussion, depends on close-ended problems, and restricts utilization of interdisciplinary…
Stress and Pore Fluid Pressure Cycles Beneath the Seismogenic Layer Recorded by Veins
NASA Astrophysics Data System (ADS)
Nüchter, J. A.; Stöckhert, B.
2006-12-01
Metamorphic rocks approaching the crustal scale brittle-ductile transition (BDT) during exhumation are expected to become increasingly affected by short term stress fluctuations related to seismic activity in the overlying seismogenic layer, while still residing in a long-term viscous environment. The (micro-)structural record of monogenetic syntaxial quartz veins in metamorphic rocks from southern Evia, Greece, yields insight into the processes and conditions just beneath the long-term BDT at temperatures of about 300 to 350° C. The following features are characteristic: 1) The veins crosscut the foliation and all syn-metamorphic structures; 2) the veins have formed from tensile fractures, with a typical length on the order of 10-1 to 101 m; 3) some veins branch symmetrically with an aperture angle of 30°, which is interpreted to indicate high crack propagation rates similar to Raleigh wave speed; 4) the veins formed during a single sealing stage by mineral precipitation in open cavities; 5) the veins show a low aspect ratio of about 10 to 100 and a characteristic lenticular shape, controlled by distributed ductile deformation of the host rock, with vein-parallel shortening by typically less than 1 %; 6) the intensity of crystal plastic deformation in the vein quartz decreases from the vein walls towards the center; 7) fluid inclusions trapped in the vein quartz record a time series of pore fluid pressure (Pf) evolution during progressive sealing, with low Pf at the vein walls (early stage) to high Pf in the vein core (final stage). These features indicate: Opening of the fractures commenced immediately after crack arrest, controlled by ductile deformation of the host rock at temperatures between about 300 and 350° C. The crack opening rate exceeded the rate of sealing, so that the quartz crystals grew into an open cavity. For opening of cracks, the effective stress on the fracture walls must be tensile and the fluid pressure must be similar to that of the magnitude of the least principal stress Pf ≍ σ3. The evolution of Pf recorded by the fluid inclusions reflects the relaxation of stress during progressive opening and sealing of the vein. This is supported by the fact that the quartz crystals grown at the fracture walls, hence early in the opening and sealing history, record a more intense deformation compared to the crystals grown lately in the centre of the vein. The structural and microstructural record of these monogenetic veins reflects an isothermal switch from brittle failure to decelerating viscous creep. The total strain accumulated is low. The following scenario is inferred: Fracturing is proposed to be a consequence of co-seismic loading related to fault slip in the overlying upper crust. Within the underlying damage zone, fractures develop and dilation causes a drop in Pf. Subsequently, the fractures open controlled by viscous creep of the host rock with a concomitant rise in Pf during stress relaxation. Sealing of the fissures to become veins takes place continuously by precipitation of minerals from the pore fluid streaming through the evolving cavity. The lenticular monogenetic veins are therefore interpreted to record a short-term and episodic process. Such type of record of exhumed rocks provides insight into earthquake-related damage beneath the seismogenic layer and into the nature of transient crustal properties in the earthquake cycle.
Open House at the ESO Headquarters
NASA Astrophysics Data System (ADS)
Madsen, C.
2006-12-01
On 15 October, the ESO Headquarters opened its doors to the public as part of the All-Campus Open House organised in connection with the inauguration of the extension of the underground line U6 from Munich to the Garching campus. The day was blessed with clear skies and plenty of sunshine, and a large number of citizens took advantage of the opportunity to visit the campus. The estimated number of visitors at ESO was close to 3000 people, a record number. Another record was set by the number of ESO staff who, in anticipation of the high num-ber of guests, volunteered to spend their Sunday at work to explain what ESO is doing and why it is important.
30 CFR 57.5040 - Exposure records.
Code of Federal Regulations, 2010 CFR
2010-07-01
... complete individual exposure of all mine personnel working in active working areas with radon daughter... personnel assigned to work in active working areas where radon daughter concentrations have been reduced to.... An average airborne radon daughter concentration for a designated active working area shall be...
Code of Federal Regulations, 2013 CFR
2013-04-01
... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Definitions. 1003.2 Section 1003.2 Foreign Relations INTER-AMERICAN FOUNDATION RULES SAFEGUARDING PERSONAL INFORMATION IN IAF RECORDS § 1003.2... number, symbol, or other identifying particular assigned to the individual. (f) The term statistical...
20 CFR 422.101 - Material included in this subpart.
Code of Federal Regulations, 2010 CFR
2010-04-01
... Section 422.101 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ORGANIZATION AND PROCEDURES General... applications for and assignment of social security numbers, maintenance of earnings records of individuals by the Social Security Administration, requests for statements of earnings or for revision of earnings...
Design and implementation of a privacy preserving electronic health record linkage tool in Chicago
Cashy, John P; Jackson, Kathryn L; Pah, Adam R; Goel, Satyender; Boehnke, Jörn; Humphries, John Eric; Kominers, Scott Duke; Hota, Bala N; Sims, Shannon A; Malin, Bradley A; French, Dustin D; Walunas, Theresa L; Meltzer, David O; Kaleba, Erin O; Jones, Roderick C; Galanter, William L
2015-01-01
Objective To design and implement a tool that creates a secure, privacy preserving linkage of electronic health record (EHR) data across multiple sites in a large metropolitan area in the United States (Chicago, IL), for use in clinical research. Methods The authors developed and distributed a software application that performs standardized data cleaning, preprocessing, and hashing of patient identifiers to remove all protected health information. The application creates seeded hash code combinations of patient identifiers using a Health Insurance Portability and Accountability Act compliant SHA-512 algorithm that minimizes re-identification risk. The authors subsequently linked individual records using a central honest broker with an algorithm that assigns weights to hash combinations in order to generate high specificity matches. Results The software application successfully linked and de-duplicated 7 million records across 6 institutions, resulting in a cohort of 5 million unique records. Using a manually reconciled set of 11 292 patients as a gold standard, the software achieved a sensitivity of 96% and a specificity of 100%, with a majority of the missed matches accounted for by patients with both a missing social security number and last name change. Using 3 disease examples, it is demonstrated that the software can reduce duplication of patient records across sites by as much as 28%. Conclusions Software that standardizes the assignment of a unique seeded hash identifier merged through an agreed upon third-party honest broker can enable large-scale secure linkage of EHR data for epidemiologic and public health research. The software algorithm can improve future epidemiologic research by providing more comprehensive data given that patients may make use of multiple healthcare systems. PMID:26104741
Design and implementation of a privacy preserving electronic health record linkage tool in Chicago.
Kho, Abel N; Cashy, John P; Jackson, Kathryn L; Pah, Adam R; Goel, Satyender; Boehnke, Jörn; Humphries, John Eric; Kominers, Scott Duke; Hota, Bala N; Sims, Shannon A; Malin, Bradley A; French, Dustin D; Walunas, Theresa L; Meltzer, David O; Kaleba, Erin O; Jones, Roderick C; Galanter, William L
2015-09-01
To design and implement a tool that creates a secure, privacy preserving linkage of electronic health record (EHR) data across multiple sites in a large metropolitan area in the United States (Chicago, IL), for use in clinical research. The authors developed and distributed a software application that performs standardized data cleaning, preprocessing, and hashing of patient identifiers to remove all protected health information. The application creates seeded hash code combinations of patient identifiers using a Health Insurance Portability and Accountability Act compliant SHA-512 algorithm that minimizes re-identification risk. The authors subsequently linked individual records using a central honest broker with an algorithm that assigns weights to hash combinations in order to generate high specificity matches. The software application successfully linked and de-duplicated 7 million records across 6 institutions, resulting in a cohort of 5 million unique records. Using a manually reconciled set of 11 292 patients as a gold standard, the software achieved a sensitivity of 96% and a specificity of 100%, with a majority of the missed matches accounted for by patients with both a missing social security number and last name change. Using 3 disease examples, it is demonstrated that the software can reduce duplication of patient records across sites by as much as 28%. Software that standardizes the assignment of a unique seeded hash identifier merged through an agreed upon third-party honest broker can enable large-scale secure linkage of EHR data for epidemiologic and public health research. The software algorithm can improve future epidemiologic research by providing more comprehensive data given that patients may make use of multiple healthcare systems. © The Author 2015. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
Analogues as a check of predicted drift stability at Yucca Mountain, Nevada
Stuckless, J.S.
2006-01-01
Calculations made by the U.S. Department of Energy's Yucca Mountain Project as part of the licensing of a proposed geologic repository in southwestern Nevada for the disposal of high-level radioactive waste, predict that emplacement tunnels will remain open with little collapse long after ground support has disintegrated. This conclusion includes the effects of anticipated seismic events. Natural analogues cannot provide a quantitative test of this conclusion, but they can provide a reasonableness test by examining the naturally occuring and anthropogenic examples of stability of subterranean openings. Available data from a variety of sources, combined with limited observations by the author, show that natural underground openings tend to resist collapse for millions of years and that anthropogenic subterranean openings have remained open from before recorded history through today. This stability is true even in seismically active areas. In fact, the archaeological record is heavily skewed toward preservation of underground structures relative to those found at the surface.
ERIC Educational Resources Information Center
Congress of the U.S., Washington, DC. House Committee on Energy and Commerce.
A discussion of H.R. 1407, a bill to establish procedures to improve the allocation and assignment to the electromagnetic spectrum centered on the current policy of allocating portions of the spectrum through lotteries and auction. This report includes a copy of the bill, the text of testimony presented and materials submitted for the record, and…
Near UV bands of jet-cooled CaO
NASA Astrophysics Data System (ADS)
Stewart, Jacob T.; Sullivan, Michael N.; Heaven, Michael C.
2016-04-01
The electronic spectrum of CaO has been recorded for the 29,800-33,150 cm-1 energy range. Jet cooling was used to obtain relatively uncongested spectra. Rotationally resolved bands have been assigned to the C1Σ+-X1Σ+ and F1∏-X transitions. These data extend the range of vibronic levels characterized for the upper states. Three additional vibronic states were observed as a short progression. One of these levels, which are of 0+ symmetry, interacts strongly with the C1Σ+, v‧ = 7 level. Possible assignments for the perturbing state are considered.
NASA Astrophysics Data System (ADS)
Durig, J. R.; Badawi, H. M.
1990-12-01
The microwave spectrum of cyclobutylcarboxaldehyde, c-C 4H 7CHO, has been recorded from 12.4 to 39.0 GHz. Two sets of a-type R-branch transitions were observed and assigned, on the basis of the rigid rotor model, to the equatorial-trans and the equatorial-gauche conformers. The rotational constants for the ground state for the equatorial-trans conformer are: A=9653.70 ± 0.47, B=2224.15 ± 0.01 and C=1986.68 ± 0.01 MHz. The lines for the first excited state of the asymmetric torsion for the equatorial-trans conformer have also been identified and assigned and, from relative intensity measurements, the frequency of the asymmetric torsion of this conformer is estimated to be 71 ± 10 cm -1. For the equatorial-gauche conformer in addition to the R-branch assignments, Q-branch assignments have been made for b- and c-type transitions for the ground state. The rotational constants for this conformer are: A=8108.08 ± 0.05, B=2554.89 ± 0.01, and C=2215.78 ± 0.01 MHz. From the Stark effect the dipole moment components for both conformers were determined. For the equatorial-trans conformer the dipole moment components were determined to be: &|μ a&| = 1.65 ± 0.01 D, &|μ b&|=0.00 (by symmetry), &|μ c&|=1.23 ± 0.01 &|μ t&|=2.06 ± 0.01 D. For the equatorial-gauge conformer the dipole moment components were determined to be: &|μ a&|=2.03 ± &|μ b&|=1.52 ± 0.04, &|μ c&|=0.83 ± 0.06 and &|μ t&|=2.66 ± 0.02 D. The infrared (3500-30 cm -1 and Raman have been recorded for the gaseous and solid states of cyclobutylcarboxaldehyde. Additionally, the Raman spectrum of the liquid phase has been recorded and qualitative depolarization values have been obtained. From variable temperature measurements of the microwave and Raman spectra, for the gaseous and liquid phases, respectively, the equatorial-gauche conformer was found to be thermodynamically preferred for the gas phase; however, it is the equatorial-trans rotamer which is most stable in the liquid. Furthermore, the only conformation present in the annealed solid is the equatorial-trans rotamer. From these data a complete vibrational assignment is proposed. The observed splitting of many of the fundamentals in the solid state indicates that there are at least two molecules per primitive cell. These results are compared to similar quantities in some related molecules.
Smith, Tristram; Aman, Michael G; Arnold, L Eugene; Silverman, Laura B; Lecavalier, Luc; Hollway, Jill; Tumuluru, Rameshwari; Hyman, Susan L; Buchan-Page, Kristin A; Hellings, Jessica; Rice, Robert R; Brown, Nicole V; Pan, Xueliang; Handen, Benjamin L
2016-10-01
The authors previously reported on a 2-by-2 randomized clinical trial of individual and combined treatment with atomoxetine (ATX) and parent training (PT) for attention-deficit/hyperactivity disorder (ADHD) symptoms and behavioral noncompliance in 128 5- to 14-year-old children with autism spectrum disorder. In the present report, they describe a 24-week extension of treatment responders and nonresponders. One-hundred seventeen participants from the acute trial (91%) entered the extension; 84 of these were in 2 subgroups: "treatment responders" (n = 43) from all 4 groups in the acute trial, seen monthly for 24 weeks, and "placebo nonresponders" (n = 41), treated with open-label ATX for 10 weeks. Participants originally assigned to PT continued PT during the extension; the remainder served as controls. Primary outcome measurements were the parent-rated Swanson, Nolan and Pelham ADHD scale and the Home Situations Questionnaire. Sixty percent (26 of 43) of treatment responders in the acute trial, including 68% of responders originally assigned to ATX, still met the response criteria at the end of the extension. The response rate of placebo nonresponders treated with 10-week open-label ATX was 37% (15 of 41), similar to the acute trial. Children receiving open-label ATX + PT were significantly more likely to be ADHD responders (53% versus 23%) and noncompliance responders (58% versus 14%) than those receiving open-label ATX alone. Most ATX responders maintained their responses during the extension. PT combined with ATX in the open-label trial appeared to improve ADHD and noncompliance outcomes more than ATX alone. Clinical trial registration information-Atomoxetine, Placebo and Parent Management Training in Autism (Strattera); http://clinicaltrials.gov; NCT00844753. Copyright © 2016 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.
Open air refuse burning video: Proton Dan the science man explores open air refuse burning
DOE Office of Scientific and Technical Information (OSTI.GOV)
Eastburn, M.D.; Sipple, J.L.; Deramo, A.R.
The goal of this video is to educate school children to the potential hazards of open air trash burning; to demonstrate alternative ways to dispose of trash; and to motivate students to take action to change the behavior of their parents with regard to trash burning. The burning of household trash, although illegal, is still a common practice in rural areas of Delaware. Enforcement has been difficult because the practice is often performed at night and is done across a wide rural area that is difficult to patrol on a continuing basis. The prohibition on trash burning (revised Regulation 13more » of The Delaware Code of Regulations Governing The Control of Air Pollution) has been in effect since 1968, but the public has been slow to comply because trash burning has been practiced for many generations and because much of the public is unaware of the environmental impacts and/or the human health risks. This video may be valuable for other States to use as a public outreach tool regarding their problems with open air refuse burning. The focus of the video is a 7th grade science class is given various assignments relating to Earth Day and preservation of natural resources. Two children in particular are given the assignment to research and report on the hazards of open air trash burning and are asked to investigate alternative ways to dispose of refuse. Upon brainstorming how to find information on the topic, the kids decide to contact the host of a popular children's science show on broadcast television named Proton Dan the Science Man (a fictitious character and show based on Bill Nye the Science Guy). The host then invites the kids to the studio where he films his show and takes them through the topic. The TV host character takes the children to several external locations like a landfill, recycling centers, etc..« less
Interactive visual exploration and refinement of cluster assignments.
Kern, Michael; Lex, Alexander; Gehlenborg, Nils; Johnson, Chris R
2017-09-12
With ever-increasing amounts of data produced in biology research, scientists are in need of efficient data analysis methods. Cluster analysis, combined with visualization of the results, is one such method that can be used to make sense of large data volumes. At the same time, cluster analysis is known to be imperfect and depends on the choice of algorithms, parameters, and distance measures. Most clustering algorithms don't properly account for ambiguity in the source data, as records are often assigned to discrete clusters, even if an assignment is unclear. While there are metrics and visualization techniques that allow analysts to compare clusterings or to judge cluster quality, there is no comprehensive method that allows analysts to evaluate, compare, and refine cluster assignments based on the source data, derived scores, and contextual data. In this paper, we introduce a method that explicitly visualizes the quality of cluster assignments, allows comparisons of clustering results and enables analysts to manually curate and refine cluster assignments. Our methods are applicable to matrix data clustered with partitional, hierarchical, and fuzzy clustering algorithms. Furthermore, we enable analysts to explore clustering results in context of other data, for example, to observe whether a clustering of genomic data results in a meaningful differentiation in phenotypes. Our methods are integrated into Caleydo StratomeX, a popular, web-based, disease subtype analysis tool. We show in a usage scenario that our approach can reveal ambiguities in cluster assignments and produce improved clusterings that better differentiate genotypes and phenotypes.
Peer Grading in Astronomy Massive Open Online Course
NASA Astrophysics Data System (ADS)
Formanek, Martin; Wenger, Matthew; Impey, Christopher; Buxner, Sanlyn
In this work we thoroughly investigate the peer grading process as it happened in the University of Arizona session based MOOC ``Astronomy: Exploring Time and Space'' offered during Spring 2015 through Coursera. Overall, 25400 learners from over 100 countries registered for this course. Of those, 14900 accessed at least one part of the course and 1332 users engaged in the peer grading. First of all we provide description of the peer graded assignments and we identify trends in behavior of people who participated in these exercises. E.g. time they spent on grading, number of assignments graded and patterns arising from comparing all three assignments. Furthermore, for the second assignment, we graded random sample of 300 essays by a group of trained undergraduate students and a group consisting of one of the course instructors together with graduate TAs and we compared results with grades from the peer grading. Specifically we look on Intraclass Correlation Coefficients for all three groups of graders to determine reliability of each group and correlations between final grades. Finally we assess factors influencing reliability of the peer graders participating in the MOOC based on the difference from our grades. This research was supported by Howard Hughes Medical Institute Grant No. 415580.
Distributed Dynamic Host Configuration Protocol (D2HCP)
Villalba, Luis Javier García; Matesanz, Julián García; Orozco, Ana Lucila Sandoval; Díaz, José Duván Márquez
2011-01-01
Mobile Ad Hoc Networks (MANETs) are multihop wireless networks of mobile nodes without any fixed or preexisting infrastructure. The topology of these networks can change randomly due to the unpredictable mobility of nodes and their propagation characteristics. In most networks, including MANETs, each node needs a unique identifier to communicate. This work presents a distributed protocol for dynamic node IP address assignment in MANETs. Nodes of a MANET synchronize from time to time to maintain a record of IP address assignments in the entire network and detect any IP address leaks. The proposed stateful autoconfiguration scheme uses the OLSR proactive routing protocol for synchronization and guarantees unique IP addresses under a variety of network conditions, including message losses and network partitioning. Simulation results show that the protocol incurs low latency and communication overhead for IP address assignment. PMID:22163856
Distributed Dynamic Host Configuration Protocol (D2HCP).
Villalba, Luis Javier García; Matesanz, Julián García; Orozco, Ana Lucila Sandoval; Díaz, José Duván Márquez
2011-01-01
Mobile Ad Hoc Networks (MANETs) are multihop wireless networks of mobile nodes without any fixed or preexisting infrastructure. The topology of these networks can change randomly due to the unpredictable mobility of nodes and their propagation characteristics. In most networks, including MANETs, each node needs a unique identifier to communicate. This work presents a distributed protocol for dynamic node IP address assignment in MANETs. Nodes of a MANET synchronize from time to time to maintain a record of IP address assignments in the entire network and detect any IP address leaks. The proposed stateful autoconfiguration scheme uses the OLSR proactive routing protocol for synchronization and guarantees unique IP addresses under a variety of network conditions, including message losses and network partitioning. Simulation results show that the protocol incurs low latency and communication overhead for IP address assignment.
An experimental water line list at 1950 K in the 6250-6670 cm-1 region
NASA Astrophysics Data System (ADS)
Rutkowski, Lucile; Foltynowicz, Aleksandra; Schmidt, Florian M.; Johansson, Alexandra C.; Khodabakhsh, Amir; Kyuberis, Aleksandra A.; Zobov, Nikolai F.; Polyansky, Oleg L.; Yurchenko, Sergei N.; Tennyson, Jonathan
2018-01-01
An absorption spectrum of H216O at 1950 K is recorded in a premixed methane/air flat flame using a cavity-enhanced optical frequency comb-based Fourier transform spectrometer. 2417 absorption lines are identified in the 6250-6670 cm-1 region with an accuracy of about 0.01 cm-1. Absolute line intensities are retrieved using temperature and concentration values obtained by tunable diode laser absorption spectroscopy. Line assignments are made using a combination of empirically known energy levels and predictions from the new POKAZATEL variational line list. 2030 of the observed lines are assigned to 2937 transitions, once blends are taken into account. 126 new energy levels of H216O are identified. The assigned transitions belong to 136 bands and span rotational states up to J = 27 .
Climbing the corporate ladder: do female and male executives follow the same route?
Lyness, K S; Thompson, D E
2000-02-01
This study compares the careers of matched samples of 69 female executives and 69 male executives by examining perceived barriers and facilitators of advancement, self-reported developmental experiences, and career histories. Consistent with tokenism theory, women reported greater barriers, such as lack of culture fit and being excluded from informal networks, and greater importance of having a good track record and developing relationships to facilitate advancement than did men. Career success, measured by organizational level and compensation, was positively related to breadth of experience and developmental assignments for both genders, but successful women were less likely than successful men to report that mentoring facilitated their advancement. Developmental experiences and career histories were similar for female and male executives, but men had more overseas assignments and women had more assignments with nonauthority relationships.