Enhanced MALDI-TOF MS Analysis of Phosphopeptides Using an Optimized DHAP/DAHC Matrix
Hou, Junjie; Xie, Zhensheng; Xue, Peng; Cui, Ziyou; Chen, Xiulan; Li, Jing; Cai, Tanxi; Wu, Peng; Yang, Fuquan
2010-01-01
Selecting an appropriate matrix solution is one of the most effective means of increasing the ionization efficiency of phosphopeptides in matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS). In this study, we systematically assessed matrix combinations of 2, 6-dihydroxyacetophenone (DHAP) and diammonium hydrogen citrate (DAHC), and demonstrated that the low ratio DHAP/DAHC matrix was more effective in enhancing the ionization of phosphopeptides. Low femtomole level of phosphopeptides from the tryptic digests of α-casein and β-casein was readily detected by MALDI-TOF-MS in both positive and negative ion mode without desalination or phosphopeptide enrichment. Compared with the DHB/PA matrix, the optimized DHAP/DAHC matrix yielded superior sample homogeneity and higher phosphopeptide measurement sensitivity, particularly when multiple phosphorylated peptides were assessed. Finally, the DHAP/DAHC matrix was applied to identify phosphorylation sites from α-casein and β-casein and to characterize two phosphorylation sites from the human histone H1 treated with Cyclin-Dependent Kinase-1 (CDK1) by MALDI-TOF/TOF MS. PMID:20339515
Physiological effects of autotoxicity due to DHAP stress on Picea schrenkiana regeneration
Yang, Li; Ruan, Xiao; Jiang, Dean; Zhang, Jianhong; Pan, Cunde; Wang, Qiang
2017-01-01
Picea Schrenkiana as one of the most important zonal vegetation was an endemic species in Middle Asia. Natural regeneration of P. Schrenkiana is a long existing problem troubling scientists. The autotoxicity of 3,4-dihydroxy-acetophenone (DHAP) was found to be a causative factor causing the failure of P. Schrenkiana natural regeneration. The effects of concentrations of DHAP treatment on the viability of root cell, activities of antioxidant enzymes and levels of P. Schrenkiana phytohormones were performed to disclose the physiological mechanism of DHAP autotoxicity. It was observed that high concentration of DHAP could inhibit the seed germination and seedling growth, but had a hormesis at low concentrations. Analyses showed that the root cells significantly lost their viability treated with high DHAP. The enzymes activities of seedlings were significantly stimulated by the treatment of 0.5 mM DHAP to give a transient increase and then decrease as DHAP concentration increased to 1.0 mM except for GR (glutathione reductase) in which DHAP treatment had little effect on its activity. Comparing with the control, an increase in the levels of phytohormones ZT (zeatin), GA3 (gibberellic acid) and IAA (indole acetic acid) was induced by the treatment of DHAP at low concentrations (0.1–0.25 mM), but the significant deficiency was found treated by high concentrations (0.5–1.0 mM). In addition, the ABA (abscisic acid) level increased in all experimental observations. These results suggested that DHAP significantly affected indices of growth and physiology, and provided some new information about different effect in P. Schrenkiana treated with DHAP. PMID:28481896
Dihydroartemisinin-piperaquine for treating uncomplicated Plasmodium falciparum malaria
Zani, Babalwa; Gathu, Michael; Donegan, Sarah; Olliaro, Piero L; Sinclair, David
2014-01-01
Background The World Health Organization (WHO) recommends Artemisinin-based Combination Therapy (ACT) for treating uncomplicated Plasmodium falciparum malaria. This review aims to assist the decision-making of malaria control programmes by providing an overview of the relative effects of dihydroartemisinin-piperaquine (DHA-P) versus other recommended ACTs. Objectives To evaluate the effectiveness and safety of DHA-P compared to other ACTs for treating uncomplicated P. falciparum malaria in adults and children. Search methods We searched the Cochrane Infectious Diseases Group Specialized Register; the Cochrane Central Register of Controlled Trials (CENTRAL) published in The Cochrane Library; MEDLINE; EMBASE; LILACS, and the metaRegister of Controlled Trials (mRCT) up to July 2013. Selection criteria Randomized controlled trials comparing a three-day course of DHA-P to a three-day course of an alternative WHO recommended ACT in uncomplicated P. falciparum malaria. Data collection and analysis Two authors independently assessed trials for eligibility and risk of bias, and extracted data. We analysed primary outcomes in line with the WHO 'Protocol for assessing and monitoring antimalarial drug efficacy’ and compared drugs using risk ratios (RR) and 95% confidence intervals (CI). Secondary outcomes were effects on gametocytes, haemoglobin, and adverse events. We assessed the quality of evidence using the GRADE approach. Main results We included 27 trials, enrolling 16,382 adults and children, and conducted between 2002 and 2010. Most trials excluded infants aged less than six months and pregnant women. DHA-P versus artemether-lumefantrine In Africa, over 28 days follow-up, DHA-P is superior to artemether-lumefantrine at preventing further parasitaemia (PCR-unadjusted treatment failure: RR 0.34, 95% CI 0.30 to 0.39, nine trials, 6200 participants, high quality evidence), and although PCR-adjusted treatment failure was below 5% for both ACTs, it was consistently lower with DHA-P (PCR-adjusted treatment failure: RR 0.42, 95% CI 0.29 to 0.62, nine trials, 5417 participants, high quality evidence). DHA-P has a longer prophylactic effect on new infections which may last for up to 63 days (PCR-unadjusted treatment failure: RR 0.71, 95% CI 0.65 to 0.78, two trials, 3200 participants, high quality evidence). In Asia and Oceania, no differences have been shown at day 28 (four trials, 1143 participants, moderate quality evidence), or day 63 (one trial, 323 participants, low quality evidence). Compared to artemether-lumefantrine, no difference was seen in prolonged QTc (low quality evidence), and no cardiac arrhythmias were reported. The frequency of other adverse events is probably similar with both combinations (moderate quality evidence). DHA-P versus artesunate plus mefloquine In Asia, over 28 days follow-up, DHA-P is as effective as artesunate plus mefloquine at preventing further parasitaemia (PCR-unadjusted treatment failure: eight trials, 3487 participants, high quality evidence). Once adjusted by PCR to exclude new infections, treatment failure at day 28 was below 5% for both ACTs in all eight trials, but lower with DHA-P in two trials (PCR-adjusted treatment failure: RR 0.41 95% CI 0.21 to 0.80, eight trials, 3482 participants, high quality evidence). Both combinations contain partner drugs with very long half-lives and no consistent benefit in preventing new infections has been seen over 63 days follow-up (PCR-unadjusted treatment failure: five trials, 2715 participants, moderate quality evidence). In the only trial from South America, there were fewer recurrent parastaemias over 63 days with artesunate plus mefloquine (PCR-unadjusted treatment failure: RR 6.19, 95% CI 1.40 to 27.35, one trial, 445 participants, low quality evidence), but no differences were seen once adjusted for new infections (PCR-adjusted treatment failure: one trial, 435 participants, low quality evidence). DHA-P is associated with less nausea, vomiting, dizziness, sleeplessness, and palpitations compared to artesunate plus mefloquine (moderate quality evidence). DHA-P was associated with more frequent prolongation of the QTc interval (low quality evidence), but no cardiac arrhythmias were reported. Authors' conclusions In Africa, dihydroartemisinin-piperaquine reduces overall treatment failure compared to artemether-lumefantrine, although both drugs have PCR-adjusted failure rates of less than 5%. In Asia, dihydroartemisinin-piperaquine is as effective as artesunate plus mefloquine, and is better tolerated. PLAIN LANGUAGE SUMMARY Dihydroartemisinin-piperaquine for treating uncomplicated malaria This review summarises trials evaluating the effects of dihydroartemisinin-piperaquine (DHA-P) compared to other artemisinin-based combination therapies recommended by the World Health Organization. After searching for relevant trials up to July 2013, we included 27 randomized controlled trials, enrolling 16,382 adults and children and conducted between 2002 and 2010. What is uncomplicated malaria and how might dihydroartemisinin-piperaquine work Uncomplicated malaria is the mild form of malaria which usually causes a fever, with or without headache, tiredness, muscle pains, abdominal pains, nausea, and vomiting. If left untreated, uncomplicated malaria can develop into severe malaria with kidney failure, breathing difficulties, fitting, unconsciousness, and eventually death. DHA-P is one of five artemisinin-based combination therapies the World Health Organization currently recommends to treat malaria. These combinations contain an artemisinin component (such as dihydroartemisinin) which works very quickly to clear the malaria parasite from the person's blood, and a longer acting drug (such as piperaquine) which clears the remaining parasites from the blood and may prevent new infections with malaria for several weeks. What the research says DHA-P versus artemether lumefantrine In studies of people living in Africa, both DHA-P and artemether-lumefantrine are very effective at treating malaria (high quality evidence). However, DHA-P cures slightly more patients than artemether-lumefantrine, and it also prevents further malaria infections for longer after treatment (high quality evidence). DHA-P and artemether-lumefantrine probably have similar side effects (moderate quality evidence). DHA-P versus artesunate plus mefloquine In studies of people living in Asia, DHA-P is as effective as artesunate plus mefloquine at treating malaria (moderate quality evidence). Artesunate plus mefloquine probably causes more nausea, vomiting, dizziness, sleeplessness, and palpitations than DHA-P (moderate quality evidence). Overall, in some people, DHA-P has been seen to cause short term changes in electrocardiographs tracing the conduction of the heart rhythm (low quality evidence), but these small changes on the electrocardiograph resolved within one week without serious consequences. PMID:24443033
Deng, Shuang; Scott, David; Myers, Douglas; Garg, Uttam
2016-01-01
Triosephosphate isomerase (TPI) is a glycolytic enzyme which catalyzes the interconversion between glyceraldehyde-3-phosphate (G3P) and dihydroxyacetone phosphate (DHAP). TPI deficiency results in accumulation of DHAP in human red blood cells and other tissues. The disease is characterized by congenital hemolytic anemia, and progressive neuromuscular dysfunction. The laboratory diagnosis is generally made by measurement of TPI activity in RBCs. Measurement of DHAP can be useful in further confirmation and follow-up of the disease. We developed HPLC/TOF-MS method for quantitation of DHAP in RBCs. The method involves simple protein precipitation, reverse phase C8 column chromatography, ion pairing with tributylamine, and long run time of 50 min to separate the two isomers (G3P and DHAP).
In vitro nonenzymatic glycation of guanosine 5'-triphosphate by dihydroxyacetone phosphate.
Li, Yuyuan; Cohenford, Menashi A; Dutta, Udayan; Dain, Joel A
2008-11-01
Dihydroxyacetone phosphate (DHAP) is a glycolytic intermediate that has been found to be significantly elevated in the erythrocytes of diabetic patients and patients with triosephosphate isomerase deficiency. DHAP spontaneously breaks down to methylglyoxal, a potent glycating agent that reacts with proteins and nucleic acids in vivo to form advanced glycation endproducts (AGEs). Like methylglyoxal, DHAP itself is also a glycating metabolite, capable of condensing with proteins and altering their structure or function. The objective of this investigation was to evaluate the susceptibility of nucleotides to nonenzymatic attack by DHAP, and to determine the factors influencing the rate and extent of nucleotide glycation by this sugar. Of the four nucleotide triphosphates (ATP, CTP, GTP and UTP) that were studied, only GTP was reactive, forming a wide range of UV and fluorescent products with DHAP. Increases in temperature and nucleotide concentration enhanced the rate and extent of GTP glycation by DHAP and promoted the heterogeneity of AGEs. Capillary electrophoresis, HPLC, and mass spectrometry allowed for a thorough analysis of the glycated products and demonstrated that the reaction of DHAP with GTP occurred via the classical Amadori pathway.
French, Nigel G.; Scoble, Judith A.; Williams, Charlotte C.; Churches, Quentin I.; Frazer, Andrew R.; Taylor, Matthew C.; Coia, Greg; Simpson, Gregory; Turner, Nicholas J.; Scott, Colin
2017-01-01
Carbon-carbon bond formation is one of the most challenging reactions in synthetic organic chemistry, and aldol reactions catalysed by dihydroxyacetone phosphate-dependent aldolases provide a powerful biocatalytic tool for combining C-C bond formation with the generation of two new stereo-centres, with access to all four possible stereoisomers of a compound. Dihydroxyacetone phosphate (DHAP) is unstable so the provision of DHAP for DHAP-dependent aldolases in biocatalytic processes remains complicated. Our research has investigated the efficiency of several different enzymatic cascades for the conversion of glycerol to DHAP, including characterising new candidate enzymes for some of the reaction steps. The most efficient cascade for DHAP production, comprising a one-pot four-enzyme reaction with glycerol kinase, acetate kinase, glycerophosphate oxidase and catalase, was coupled with a DHAP-dependent fructose-1,6-biphosphate aldolase enzyme to demonstrate the production of several rare chiral sugars. The limitation of batch biocatalysis for these reactions and the potential for improvement using kinetic modelling and flow biocatalysis systems is discussed. PMID:29112947
Hartley, Carol J; French, Nigel G; Scoble, Judith A; Williams, Charlotte C; Churches, Quentin I; Frazer, Andrew R; Taylor, Matthew C; Coia, Greg; Simpson, Gregory; Turner, Nicholas J; Scott, Colin
2017-01-01
Carbon-carbon bond formation is one of the most challenging reactions in synthetic organic chemistry, and aldol reactions catalysed by dihydroxyacetone phosphate-dependent aldolases provide a powerful biocatalytic tool for combining C-C bond formation with the generation of two new stereo-centres, with access to all four possible stereoisomers of a compound. Dihydroxyacetone phosphate (DHAP) is unstable so the provision of DHAP for DHAP-dependent aldolases in biocatalytic processes remains complicated. Our research has investigated the efficiency of several different enzymatic cascades for the conversion of glycerol to DHAP, including characterising new candidate enzymes for some of the reaction steps. The most efficient cascade for DHAP production, comprising a one-pot four-enzyme reaction with glycerol kinase, acetate kinase, glycerophosphate oxidase and catalase, was coupled with a DHAP-dependent fructose-1,6-biphosphate aldolase enzyme to demonstrate the production of several rare chiral sugars. The limitation of batch biocatalysis for these reactions and the potential for improvement using kinetic modelling and flow biocatalysis systems is discussed.
Berber, Ilhami; Erkurt, Mehmet Ali; Kuku, Irfan; Kaya, Emin; Bag, Harika Gozukara; Nizam, Ilknur; Koroglu, Mustafa; Ozgul, Mustafa
2016-02-01
This study aimed to evaluate the efficiency of DHAP regimen plus filgrastim for mobilization of stem cells in patients with recurrent and/or refractory lymphoma. Thirty-four patients who took DHAP as salvage therapy prior to autologous stem cell transplantation were included. After chemotherapies, 2 cycles of DHAP plus filgrastim were administered to the patients. Stem cells from 32 patients (94%) were collected on median 11th day (8-12), and the median collected CD34(+) cell dose was 9.7 × 10(6)/kg (range 3.8-41.6). DHAP plus filgrastim was found to be an effective chemotherapy regimen in mobilizing CD34(+) stem cells into the peripheral. Copyright © 2016 Elsevier Ltd. All rights reserved.
Recent advances in the synthesis of rare sugars using DHAP-dependent aldolases.
Li, Aimin; Cai, Li; Chen, Zhou; Wang, Mayan; Wang, Ning; Nakanishi, Hideki; Gao, Xiao-Dong; Li, Zijie
2017-11-27
The occurrence rates of non-communicable diseases like obesity, diabetes and hyperlipidemia have increased remarkably due to excessive consumption of a high-energy diet. Rare sugars therefore have become increasingly attractive owing to their unique nutritional properties. In the past two decades, various rare sugars have been successfully prepared guided by the "Izumoring strategy". As a valuable complement to the Izumoring approach, the controllable dihydroxyacetone phosphate (DHAP)-dependent aldolases have generally predictable regio- and stereoselectivity, which makes them powerful tools in C-C bond construction and rare sugar production. However, the main disadvantage for this group of aldolases is their strict substrate specificity toward the donor molecule DHAP, a very expensive and relatively unstable compound. Among the current methods involving DHAP, the one that couples DHAP production from inexpensive starting materials (for instance, glycerol, DL-glycerol 3-phosphate, dihydroxyacetone, and glucose) with aldol condensation appears to be the most promising. This review thus focuses on recent advances in the application of L-rhamnulose-1-phosphate aldolase (RhaD), L-fuculose-1-phosphate aldolase (FucA), and D-fructose-1,6-bisphosphate aldolase (FruA) for rare sugar synthesis in vitro and in vivo, while illustrating strategies for supplying DHAP in efficient and economical ways. Copyright © 2017 Elsevier Ltd. All rights reserved.
Autotoxicity and allelopathy of 3,4-dihydroxyacetophenone isolated from Picea schrenkiana needles.
Ruan, Xiao; Li, Zhao-Hui; Wang, Qiang; Pan, Cun-De; Jiang, De-An; Wang, G Geoff
2011-10-24
Bioassay-guided fractionation of the diethyl ether fraction of a water extract of Picea schrenkiana needles led to the isolation of the phenolic compound 3,4-dihydroxy- acetophenone (DHAP). The allelopathic effects of DHAP were evaluated under laboratory conditions on P. schrenkiana, rice (Oryza sativa L.), wheat (Triticum aestivum L.), radish (Raphanus sativus L.), lettuce (Latuca sativa L.), cucumber (Cucumis sativus L.) and mung bean (Phaseolus radiatus L.). DHAP significantly inhibited seed germination and seedling growth of P. schrenkiana at concentrations of 2.5 mM and 0.5 mM (p < 0.05). Soil analysis revealed that P. schrenkiana forest soils contained exceptionally high DHAP concentrations (mean = 0.51 ± 0.03 mg/g dry soil), sufficient to inhibit natural P. schrenkiana recruitment. DHAP also exhibited strong allelopathic potential. It significantly inhibited wheat and lettuce seed germination at concentrations of 1 mM and 0.5 mM (p < 0.05). The active compound also completely inhibited root growth of the six test species at high concentrations. Our results suggest a dual role of DHAP, both as an allelochemical and as an autotoxicant. The potential for a single plant needle-leached compound to influence both inter- and intra-specific interactions emphasized the complex effects that plant secondary metabolites might have on plant population and community structure.
Jovanović, Marko; Peter-Katalinić, Jasna
2016-02-01
Oligosaccharides represent complex class of analytes for mass spectrometric analysis due to the high variety of structural isomers concerning glycosidic linkages and possible branching. A systematic study of the negative ion mode matrix-assisted laser desorption/ionization (MALDI) mass spectrometry of various neutral oligosaccharides under selection of an appropriate matrix, like 2,5-dihydroxyacetophenone (2,5-DHAP) is reported here, without commonly used anion dopant strategies. Nevertheless, we were able to generate relevant in-source decay (ISD) cross-ring fragment ions, typically obtained in the negative ion mode. Data observed indicate that the intrinsic property of the terminal non-reduced aldose is crucial for this behavior. A systematic study of the post source decay (PSD) of molecular, pseudomolecular and ISD cross-ring cleavage precursor ions is reported here. A direct comparison of the positive and negative ion mode MALDI MS1 and PSD behavior of neutral oligosaccharides could also be performed under the use of the same matrix preparation, because 2,5-DHAP is fully compatible with positive ion mode acquisition. We found that PSD spectra of deprotonated neutral oligosaccharides obtained in the negative ion mode are richer, because they contained both glycosidic and cross-ring fragment ions. However, we also found that cross-ring fragment ions are readily produced in the positive ion mode when potassiated precursor ions were selected. In addition, we show evidence that non-anionic dopants and specific instrumental parameters can also significantly influence the ISD fragmentation. Taken together, our results should increase our understanding of oligosaccharide behavior in the negative ion mode as well as increase our knowledge regarding many aspects of in-source MALDI chemistry. Copyright © 2016 John Wiley & Sons, Ltd.
Enya, Mayu; Aoyagi, Keiko; Hishikawa, Yoshihiro; Yoshimura, Azusa; Mitsukura, Koichi; Maruyama, Kiyofumi
2012-01-01
The gene dad encoding 2,4'-dihydroxyacetophenone (DHAP) dioxygenase was cloned from Burkholderia sp. AZ11. The initiation codon GTG was converted to ATG for high-level expression of the enzyme in Escherichia coli. The enzyme was moderately thermostable, and the recombinant enzyme was briefly purified. The enzyme (M(r)=90 kDa) was a homotetramer with a subunit M(r) of 23 kDa. It contained 1.69 mol of non-heme iron, and had a dark gray color. On anaerobic incubation of it with DHAP, the absorption at around 400 nm increased due to the formation of an enzyme-DHAP complex. Multiple sequence alignment suggested that His77, His79, His115, and Glu96 in the cupin fold were possible metal ligands. The apparent K(m) for DHAP and the apparent V(max) were estimated to be 1.60 µM and 6.28 µmol/min/mg respectively. 2-Hydroxyacetophenone was a poor substrate. CuCl(2) and HgCl(2) strongly inhibited the enzyme, while FeSO(4) weakly activated it.
Piano, Valentina; Nenci, Simone; Magnani, Francesca; Aliverti, Alessandro; Mattevi, Andrea
2016-12-02
Although the precise functions of ether phospholipids are still poorly understood, significant alterations in their physiological levels are associated either to inherited disorders or to aggressive metastatic cancer. The essential precursor, alkyl-dihydroxyacetone phosphate (DHAP), for all ether phospholipids species is synthetized in two consecutive reactions performed by two enzymes sitting on the inner side of the peroxisomal membrane. Here, we report the characterization of the recombinant human DHAP acyl-transferase, which performs the first step in alkyl-DHAP synthesis. By exploring several expression systems and designing a number of constructs, we were able to purify the enzyme in its active form and we found that it is tightly bound to the membrane through the N-terminal residues. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.
LowKam, Clotilde; Liotard, Brigitte; Sygusch, Jurgen
2010-07-02
Tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes is a class I aldolase that exhibits a remarkable lack of chiral discrimination with respect to the configuration of hydroxyl groups at both C3 and C4 positions. The enzyme catalyzes the reversible cleavage of four diastereoisomers (fructose 1,6-bisphosphate (FBP), psicose 1,6-bisphosphate, sorbose 1,6-bisphosphate, and tagatose 1,6-bisphosphate) to dihydroxyacetone phosphate (DHAP) and d-glyceraldehyde 3-phosphate with high catalytic efficiency. To investigate its enzymatic mechanism, high resolution crystal structures were determined of both native enzyme and native enzyme in complex with dihydroxyacetone-P. The electron density map revealed a (alpha/beta)(8) fold in each dimeric subunit. Flash-cooled crystals of native enzyme soaked with dihydroxyacetone phosphate trapped a covalent intermediate with carbanionic character at Lys(205), different from the enamine mesomer bound in stereospecific class I FBP aldolase. Structural analysis indicates extensive active site conservation with respect to class I FBP aldolases, including conserved conformational responses to DHAP binding and conserved stereospecific proton transfer at the DHAP C3 carbon mediated by a proximal water molecule. Exchange reactions with tritiated water and tritium-labeled DHAP at C3 hydrogen were carried out in both solution and crystalline state to assess stereochemical control at C3. The kinetic studies show labeling at both pro-R and pro-S C3 positions of DHAP yet detritiation only at the C3 pro-S-labeled position. Detritiation of the C3 pro-R label was not detected and is consistent with preferential cis-trans isomerism about the C2-C3 bond in the carbanion as the mechanism responsible for C3 epimerization in tagatose-1,6-bisphosphate aldolase.
Structure of a Class I Tagatose-1,6-bisphosphate Aldolase
LowKam, Clotilde; Liotard, Brigitte; Sygusch, Jurgen
2010-01-01
Tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes is a class I aldolase that exhibits a remarkable lack of chiral discrimination with respect to the configuration of hydroxyl groups at both C3 and C4 positions. The enzyme catalyzes the reversible cleavage of four diastereoisomers (fructose 1,6-bisphosphate (FBP), psicose 1,6-bisphosphate, sorbose 1,6-bisphosphate, and tagatose 1,6-bisphosphate) to dihydroxyacetone phosphate (DHAP) and d-glyceraldehyde 3-phosphate with high catalytic efficiency. To investigate its enzymatic mechanism, high resolution crystal structures were determined of both native enzyme and native enzyme in complex with dihydroxyacetone-P. The electron density map revealed a (α/β)8 fold in each dimeric subunit. Flash-cooled crystals of native enzyme soaked with dihydroxyacetone phosphate trapped a covalent intermediate with carbanionic character at Lys205, different from the enamine mesomer bound in stereospecific class I FBP aldolase. Structural analysis indicates extensive active site conservation with respect to class I FBP aldolases, including conserved conformational responses to DHAP binding and conserved stereospecific proton transfer at the DHAP C3 carbon mediated by a proximal water molecule. Exchange reactions with tritiated water and tritium-labeled DHAP at C3 hydrogen were carried out in both solution and crystalline state to assess stereochemical control at C3. The kinetic studies show labeling at both pro-R and pro-S C3 positions of DHAP yet detritiation only at the C3 pro-S-labeled position. Detritiation of the C3 pro-R label was not detected and is consistent with preferential cis-trans isomerism about the C2–C3 bond in the carbanion as the mechanism responsible for C3 epimerization in tagatose-1,6-bisphosphate aldolase. PMID:20427286
Miller, Anthony R.; North, Justin A.; Wildenthal, John A.
2018-01-01
ABSTRACT 5′-Methyl-thioadenosine (MTA) is a dead-end, sulfur-containing metabolite and cellular inhibitor that arises from S-adenosyl-l-methionine-dependent reactions. Recent studies have indicated that there are diverse bacterial methionine salvage pathways (MSPs) for MTA detoxification and sulfur salvage. Here, via a combination of gene deletions and directed metabolite detection studies, we report that under aerobic conditions the facultatively anaerobic bacterium Rhodopseudomonas palustris employs both an MTA-isoprenoid shunt identical to that previously described in Rhodospirillum rubrum and a second novel MSP, both of which generate a methanethiol intermediate. The additional R. palustris aerobic MSP, a dihydroxyacetone phosphate (DHAP)-methanethiol shunt, initially converts MTA to 2-(methylthio)ethanol and DHAP. This is identical to the initial steps of the recently reported anaerobic ethylene-forming MSP, the DHAP-ethylene shunt. The aerobic DHAP-methanethiol shunt then further metabolizes 2-(methylthio)ethanol to methanethiol, which can be directly utilized by O-acetyl-l-homoserine sulfhydrylase to regenerate methionine. This is in contrast to the anaerobic DHAP-ethylene shunt, which metabolizes 2-(methylthio)ethanol to ethylene and an unknown organo-sulfur intermediate, revealing functional diversity in MSPs utilizing a 2-(methylthio)ethanol intermediate. When MTA was fed to aerobically growing cells, the rate of volatile methanethiol release was constant irrespective of the presence of sulfate, suggesting a general housekeeping function for these MSPs up through the methanethiol production step. Methanethiol and dimethyl sulfide (DMS), two of the most important compounds of the global sulfur cycle, appear to arise not only from marine ecosystems but from terrestrial ones as well. These results reveal a possible route by which methanethiol might be biologically produced in soil and freshwater environments. PMID:29636438
Substrate specificity and thermostability of the dehairing alkaline protease from Bacillus pumilus.
Wan, Min-Yuan; Wang, Hai-Yan; Zhang, Yi-Zheng; Feng, Hong
2009-11-01
An alkaline protease (DHAP) from Bacillus pumilus has shown great potential in hide dehairing. To get better insights on its catalytic properties for application, the substrate specificity and thermostability were investigated using five natural proteins and nine synthetic peptides. The results showed that DHAP could hydrolyze five proteins tested here in different specificity. Collagen, a component of animal skin, was more resistant to hydrolysis than casein, fibrin, and gelatin. Among the synthetic peptides, the enzyme showed activity mainly with tetrapeptide substrates with the catalytic efficiency in order of Phe>Leu>Ala at P1 site, although k(m) value for AAVA-pN is much lower than that for AAPL-pN and AAPF-pN. With tripeptide substrates, smaller side-chain group (Gly) at P1 site was not hydrolyzed by DHAP. The enzyme showed good thermostability below 60 degrees C, and lost activity so quickly above 70 degrees C. The thermostability was largely dependent on metal ion, especially Ca(2+), although other ions, like Mg(2+), Mn(2+), and Co(2+), could sustain stability at certain extent within limited time. Cu(2+), Fe(2+), as well as Al(3+), did not support the enzyme to retain activity at 60 degrees C even in 5 min. In addition, the selected metal ions could coordinate calcium in improvement or destruction of thermostability for DHAP.
Gisselbrecht, Christian; Glass, Bertram; Mounier, Nicolas; Singh Gill, Devinder; Linch, David C.; Trneny, Marek; Bosly, Andre; Ketterer, Nicolas; Shpilberg, Ofer; Hagberg, Hans; Ma, David; Brière, Josette; Moskowitz, Craig H.; Schmitz, Norbert
2010-01-01
Purpose Salvage chemotherapy followed by high-dose therapy and autologous stem-cell transplantation (ASCT) is the standard treatment for relapsed diffuse large B-cell lymphoma (DLBCL). Salvage regimens have never been compared; their efficacy in the rituximab era is unknown. Patients and Methods Patients with CD20+ DLBCL in first relapse or who were refractory after first-line therapy were randomly assigned to either rituximab, ifosfamide, etoposide, and carboplatin (R-ICE) or rituximab, dexamethasone, high-dose cytarabine, and cisplatin (R-DHAP). Responding patients received high-dose chemotherapy and ASCT. Results The median age of the 396 patients enrolled (R-ICE, n = 202; R-DHAP, n = 194) was 55 years. Similar response rates were observed after three cycles of R-ICE (63.5%; 95% CI, 56% to 70%) and R-DHAP (62.8%; 95 CI, 55% to 69%). Factors affecting response rates (P < .001) were refractory disease/relapse less than versus more than 12 months after diagnosis (46% v 88%, respectively), International Prognostic Index (IPI) of more than 1 versus 0 to 1 (52% v 71%, respectively), and prior rituximab treatment versus no prior rituximab (51% v 83%, respectively). There was no significant difference between R-ICE and R-DHAP for 3-year event-free survival (EFS) or overall survival. Three-year EFS was affected by prior rituximab treatment versus no rituximab (21% v 47%, respectively), relapse less than versus more than 12 months after diagnosis (20% v 45%, respectively), and IPI of 2 to 3 versus 0 to 1 (18% v 40%, respectively). In the Cox model, these parameters were significant (P < .001). Conclusion In patients who experience relapse more than 12 months after diagnosis, prior rituximab treatment does not affect EFS. Patients with early relapses after rituximab-containing first-line therapy have a poor prognosis, with no difference between the effects of R-ICE and R-DHAP. PMID:20660832
Characterization of human triosephosphate isomerase S-nitrosylation.
Romero, Jorge Miguel; Carrizo, María Elena; Curtino, Juan Agustín
2018-07-01
Triosephosphate isomerase (TPI), the glycolytic enzyme that catalyzes the isomerization of dihydroxyacetone phosphate (DHAP) to glyceraldehyde-3-phosphate (G3P), has been frequently identified as a target of S-nitrosylation by proteomic studies. However, the effect of S-nitrosylation on its activity has only been explored in plants and algae. Here, we describe the in vitro S-nitrosylation of human TPI (hTPI), and the effect of the modification on its enzymatic parameters. NO-incorporation into the enzyme cysteine residues occurred by a time-dependent S-transnitrosylation from both, S-nitrosocysteine (CySNO) and S-nitrosoglutathione (GSNO), with CySNO being the more efficient NO-donor. Both X-ray crystal structure and mass spectrometry analyses showed that only Cys217 was S-nitrosylated. hTPI S-nitrosylation produced a 30% inhibition of the Vmax of the DHAP conversion to G3P, without affecting the Km for DHAP. This is the first study describing features of human TPI S-nitrosylation. Copyright © 2018 Elsevier Inc. All rights reserved.
Matsushika, Akinori; Hoshino, Tamotsu
2015-12-01
The Saccharomyces cerevisiae HAP4 gene encodes a transcription activator that plays a key role in controlling the expression of genes involved in mitochondrial respiration and reductive pathways. This work examines the effect of knockout of the HAP4 gene on aerobic ethanol production in a xylose-utilizing S. cerevisiae strain. A hap4-deleted recombinant yeast strain (B42-DHAP4) showed increased maximum concentration, production rate, and yield of ethanol compared with the reference strain MA-B42, irrespective of cultivation medium (glucose, xylose, or glucose/xylose mixtures). Notably, B42-DHAP4 was capable of producing ethanol from xylose as the sole carbon source under aerobic conditions, whereas no ethanol was produced by MA-B42. Moreover, the rate of ethanol production and ethanol yield (0.44 g/g) from the detoxified hydrolysate of wood chips was markedly improved in B42-DHAP4 compared to MA-B42. Thus, the results of this study support the view that deleting HAP4 in xylose-utilizing S. cerevisiae strains represents a useful strategy in ethanol production processes.
Direct heteroarylation polymerization: guidelines for defect-free conjugated polymers.
Bura, Thomas; Beaupré, Serge; Légaré, Marc-André; Quinn, Jesse; Rochette, Etienne; Blaskovits, J Terence; Fontaine, Frédéric-Georges; Pron, Agnieszka; Li, Yuning; Leclerc, Mario
2017-05-01
Direct (hetero)arylation polymerization (DHAP) has emerged as a valuable and atom-economical alternative to traditional cross-coupling methods for the synthesis of low-cost and efficient conjugated polymers for organic electronics. However, when applied to the synthesis of certain (hetero)arene-based materials, a lack of C-H bond selectivity has been observed. To prevent such undesirable side-reactions, we report the design and synthesis of new, bulky, phosphine-based ligands that significantly enhance selectivity of the DHAP process for both halogenated and non-halogenated electron-rich and electron-deficient thiophene-based comonomers. To better understand the selectivity issues, density functional theory (DFT) calculations have been performed on various halogenated and non-halogenated electron-rich and electron-deficient thiophene-based comonomers. Calculations showed that the presence of bromine atoms decreases the energy of activation ( E a ) of the adjacent C-H bonds, allowing undesirable β-defects for some brominated aromatic units. Both calculations and the new ligands should lead to the rational design of monomers and methods for the preparation of defect-free conjugated polymers from DHAP.
Bura, Thomas; Beaupré, Serge; Légaré, Marc-André; Quinn, Jesse; Rochette, Etienne; Blaskovits, J. Terence; Fontaine, Frédéric-Georges; Pron, Agnieszka; Li, Yuning
2017-01-01
Direct (hetero)arylation polymerization (DHAP) has emerged as a valuable and atom-economical alternative to traditional cross-coupling methods for the synthesis of low-cost and efficient conjugated polymers for organic electronics. However, when applied to the synthesis of certain (hetero)arene-based materials, a lack of C–H bond selectivity has been observed. To prevent such undesirable side-reactions, we report the design and synthesis of new, bulky, phosphine-based ligands that significantly enhance selectivity of the DHAP process for both halogenated and non-halogenated electron-rich and electron-deficient thiophene-based comonomers. To better understand the selectivity issues, density functional theory (DFT) calculations have been performed on various halogenated and non-halogenated electron-rich and electron-deficient thiophene-based comonomers. Calculations showed that the presence of bromine atoms decreases the energy of activation (E a) of the adjacent C–H bonds, allowing undesirable β-defects for some brominated aromatic units. Both calculations and the new ligands should lead to the rational design of monomers and methods for the preparation of defect-free conjugated polymers from DHAP. PMID:28966781
Hipkiss, Alan R
2010-10-01
Because accumulation of altered proteins is the most common biochemical symptom of aging, it is at least possible that such proteotoxicity may cause aging and influence life span. The life span of the nematode worm Caenorhabditis elegans is strongly influenced by changes in the intracellular concentration of methylglyoxal (MG), a putative source of much age-related proteotoxicity and organelle, cellular, and molecular dysfunction. Glycerol has recently been shown to shorten, whereas oxaloacetate has been found to extend, life span in C. elegans. It is suggested here that glycerol and oxaloacetate exert opposing effects on MG formation in C. elegans. It is proposed that, if not secreted by aquaporin, glycerol is converted to glycerol phosphate and then to dihydroxyacetone phosphate (DHAP) via a reaction requiring nicotinamide adenine dinucleotide (NAD(+)). This inhibits operation of the glycerol phosphate cycle in which DHAP is converted into glycerol phosphate, which concomitantly regenerates NAD(+) from NADH, thereby ensuring glycolytic oxidation of glyceraldehyde-3-phosphate (G3P). Because DHAP and G3P spontaneously decompose into MG, and NAD(+) is required for conversion of G3P into phosphoglycerate, the glycerol-induced increased DHAP formation and decreased NAD(+) availability will increase the potential for MG generation. In contrast, oxaloacetate may decrease MG generation by stimulating the operation of the malate-oxaloacetate shuttle, in which oxaloacetate is converted to malate, which regenerates NAD(+) from NADH. By the ensuing G3P oxidation, increased NAD(+) availability will decrease the potential for MG formation. It should be noted that mitochondria are involved in the operation of the above cycle/shuttles and that increased NAD(+) availability also stimulates those sirtuin activities that increase mitogenesis and mitochondrial activity via effects on signal transduction and gene expression, which frequently accompany dietary restriction-induced life span extension.
Koenigsmann, M; Casper, J; Kahl, C; Basara, N; Sayer, H G; Behre, G; Theurich, S; Christopeit, M; Mohren, M; Reichle, A; Metzner, B; Ganser, A; Stadler, M; Uharek, L; Balleisen, L; Hinke, A; Hinke, R; Niederwieser, D
2014-03-01
Since the outcome of relapsed/refractory aggressive non-Hodgkin's lymphoma (NHL) is highly variable, a risk-adapted treatment approach was evaluated. After two cycles of DHAP, patients received high-dose treosulfan/etoposide/carboplatinum (TEC) and autologous stem cell rescue. After TEC, low-risk patients with late relapse (>1 year after first CR who achieved CR after DHAP received no further treatment. Patients with late relapse who achieved CR or PR only after TEC underwent a second cycle of TEC. High-risk patients with early relapse/refractory disease received treosulfan/fludarabine followed by allogeneic transplantation. Rituximab was added in patients with B-cell lymphoma (86%). At entry, 36% of all 57 patients had refractory disease, 32% early and 32% late relapse. During DHAP treatment, progression occurred in 32% of patients. Of 33 patients who received TEC, 5 received second TEC and 15 allogeneic transplantation. Main toxicity after TEC was oral mucositis (CTC grades 3 and 4 in 50% and 13%, respectively). In total, 42% patients achieved CR. Median OS was 21.4 months for all patients and 32.6 for those who underwent allogeneic transplantation. International prognostic index (IPI) at study entry was highly discriminative at predicting OS (P<0.0001). Risk-adapted, treosulfan-based therapy with auto- and allo-SCT is feasible. Long-term survival is possible with allogeneic transplantation.
Reyes, Archie C; Koudelka, Astrid P; Amyes, Tina L; Richard, John P
2015-04-29
The side chain cation of R269 lies at the surface of l-glycerol 3-phosphate dehydrogenase (GPDH) and forms an ion pair to the phosphodianion of substrate dihydroxyacetone phosphate (DHAP), which is buried at the nonpolar protein interior. The R269A mutation of GPDH results in a 110-fold increase in K(m) (2.8 kcal/mol effect) and a 41,000-fold decrease in k(cat) (6.3 kcal/mol effect), which corresponds to a 9.1 kcal/mol destabilization of the transition state for GPDH-catalyzed reduction of DHAP by NADH. There is a 6.7 kcal/mol stabilization of the transition state for the R269A mutant GPDH-catalyzed reaction by 1.0 M guanidinium ion, and the transition state for the reaction of the substrate pieces is stabilized by an additional 2.4 kcal/mol by their covalent attachment at wildtype GPDH. These results provide strong support for the proposal that GPDH invests the 11 kcal/mol intrinsic phosphodianion binding energy of DHAP in trapping the substrate at a nonpolar active site, where strong electrostatic interactions are favored, and obtains a 9 kcal/mol return from stabilizing interactions between the side chain cation and transition state trianion. We propose a wide propagation for the catalytic motif examined in this work, which enables strong transition state stabilization from enzyme-phosphodianion pairs.
Tixier, F; Ranchon, F; Iltis, A; Vantard, N; Schwiertz, V; Bachy, E; Bouafia-Sauvy, F; Sarkozy, C; Tournamille, J F; Gyan, E; Salles, G; Rioufol, C
2017-12-01
Optimal salvage chemotherapy regimen for patients with relapsed or refractory Hodgkin and non-Hodgkin lymphoma remains unclear but often based on platinum regimens. This retrospective study assesses in real life the toxicities profiles of patients with relapsed or refractory lymphoma treated with DHA (dexamethasone, high dose aracytine cytarabine) plus platinum salt (dexamethasone-High dose aracytine (cis)platin (DHAP), dexamethasone-High dose aracytine carboplatin (DHAC), or dexamethasone-High dose aracytine Oxaliplatin (DHAOX)), from February 2007 to May 2013 in 2 French hospitals. Toxicities were recorded from medical files and assessed according to the National Cancer Institute Common Toxicity Criteria version 3.0. Potential risk factors of renal insufficiency were tested by univariate analyses. A total of 276 patients were treated: 168 with DHAP (60.9%), 79 with DHAOX (28.6%), and 29 with DHAC (10.5%). Rituximab was associated in 80.1% of patients (n = 221). Renal failure was reported in 97 patients, mainly with cisplatin regimen (86.6%) leading to 8.9% grade III to IV renal failure (P = .001). Renal insufficiency was reversible in most patients but remained persistent in 24, with all of them being treated with DHAP except 1. Cisplatin-based regimen (50.0% versus 12.0%, P < .05) and female (44.6% versus 29.7%, P < .05) appeared to be at higher risks of renal failure. Platinum cumulative dose is a significant risk factor of nephrotoxicity. Hematologic toxicity was more frequent with carboplatin and cisplatin with at least 1 event (all toxicity grade) respectively in 79.3% and 71.4% of patients treated (P < .005). Auditory toxicity was mainly reported with cisplatin (n = 19; 4 grade I-II and 15 grade III-IV). Oxaliplatin was implicated in 77.6% of neurotoxicity (n = 59), mainly moderate (grade I-II). In conclusion, DHAOX and DHAC regimens have more favorable toxicity profile than DHAP regimen. Their lack of renal toxicity makes them attractive regimens, which may be interesting for patients eligible for autologous stem cell transplantation. Nevertheless, these results have to be confirmed by the therapeutic efficacy of these 3 regimens. Copyright © 2016 John Wiley & Sons, Ltd.
Reyes, Archie C; Amyes, Tina L; Richard, John P
2016-11-23
The stabilization of the transition state for hlGPDH-catalyzed reduction of DHAP due to the action of the phosphodianion of DHAP and the cationic side chain of R269 is between 12.4 and 17 kcal/mol. The R269A mutation of glycerol-3-phosphate dehydrogenase (hlGPDH) results in a 9.1 kcal/mol destabilization of the transition state for enzyme-catalyzed reduction of dihydroxyacetone phosphate (DHAP) by NADH, and there is a 6.7 kcal/mol stabilization of this transition state by 1.0 M guanidine cation (Gua + ) [J. Am. Chem. Soc. 2015, 137, 5312-5315]. The R269A mutant shows no detectable activity toward reduction of glycolaldehyde (GA), or activation of this reaction by 30 mM HPO 3 2- . We report the unprecedented self-assembly of R269A hlGPDH, dianions (X 2- = FPO 3 2- , HPO 3 2- , or SO 4 2- ), Gua + and GA into a functioning catalyst of the reduction of GA, and fourth-order reaction rate constants k cat /K GA K X K Gua . The linear logarithmic correlation (slope = 1.0) between values of k cat /K GA K X for dianion activation of wildtype hlGPDH-catalyzed reduction of GA and k cat /K GA K X K Gua shows that the electrostatic interaction between exogenous dianions and the side chain of R269 is not significantly perturbed by cutting hlGPDH into R269A and Gua + pieces. The advantage for connection of hlGPDH (R269A mutant + Gua + ) and substrate pieces (GA + HP i ) pieces, (ΔG S ‡ ) HPi+E+Gua = 5.6 kcal/mol, is nearly equal to the sum of the advantage to connection of the substrate pieces, (ΔG S ‡ ) GA+HPi = 3.3 kcal/mol, for wildtype hlGPDH-catalyzed reaction of GA + HP i , and for connection of the enzyme pieces, (ΔG S ‡ ) E+Gua = 2.4 kcal/mol, for Gua + activation of the R269A hlGPDH-catalyzed reaction of DHAP.
Electrophilic properties of common MALDI matrix molecules
NASA Astrophysics Data System (ADS)
Lippa, T. P.; Eustis, S. N.; Wang, D.; Bowen, K. H.
2007-11-01
The negative ion photoelectron spectra of the following MALDI matrix molecules have been measured: 3-carboxypyridine (nicotinic acid), 2,5-dihydroxybenzoic acid (DHB), 3,5-dimethoxy-4-hydroxycinnamic acid (sinapinic acid), 2,6-dihydroxyacetophenone (DHAP), 3-(4-hydroxy-3-methoxyphenyl)-2-propenoic acid (ferulic acid), 3-hydroxy-2-pyridinecarboxylic acid (3HPA), and 2,6-pyridinedicarboxylic acid (dipicolinic acid). Adiabatic electron affinities and vertical detachment energies were extracted from these spectra and reported. In addition, electron affinities were calculated for DHAP, ferulic acid, dipicolinic acid and sinapinic acid. Photoelectron spectra were also measured for the dimer anions of DHB and nicotinic acid and for the fragment anion in which alpha-cyano-cinnamic acid had lost a CO2 unit. Together, these results augment the database of presently available electrophilic data on common matrix molecules along with some of their dimers and fragments.
Method for preparing dioxyheterocycle-based electrochromic polymers
DOE Office of Scientific and Technical Information (OSTI.GOV)
Reynolds, John R.; Estrada, Leandro; Deininger, James
A method for preparing a conjugated polymer involves a DHAP polymerization of a 3,4-dioxythiophene, 3,4-dioxyfuran, or 3,4-dioxypyrrole and, optionally, at least one second conjugated monomer in the presence of a Pd or Ni comprising catalyst, an aprotic solvent, a carboxylic acid at a temperature in excess of 120.degree. C. At least one of the monomers is substituted with hydrogen reactive functionalities and at least one of the monomers is substituted with a Cl, Br, and/or I. The polymerization can be carried out at temperature of 140.degree. C. or more, and the DHAP polymerization can be carried out without a phosphinemore » ligand or a phase transfer agent. The resulting polymer can display dispersity less than 2 and have a degree of polymerization in excess of 10.« less
Garcia-Junceda, E; Shen, G J; Sugai, T; Wong, C H
1995-07-01
Three DHAP-dependent aldolases, rhamnulose-1-phosphate aldolase (Rham-1PA), fuculose-1-phosphate aldolase (Fuc-1PA) and tagatose-1,6-diphosphate aldolase (TDPA) have been cloned and overexpressed in Escherichia coli using two different expression vectors: pTrcHis for the expression of Rham-1PA and Fuc-1PA and pRSET for the expression of TDPA. In each case the recombinant enzyme is synthesized as a fusion protein with a hexahistidine tag on the N-terminus. The three enzymes have been purified in only one step by chelation affinity chromatography. The effects of cultivation temperature and concentration of inducer have been studied in order to optimize the expression of the recombinant proteins and to avoid the formation of inclusion bodies.
Mao, Xiangzhao; Liu, Qianqian; Qiu, Yongqian; Fan, Xiaoqin; Han, Qingqing; Liu, Yanjun; Zhang, Lujia; Xue, Changhu
2017-05-10
Phosphatidylserine (PS) and docosahexaenoic acid-phosphatidylserine (DHA-PS) have significant nutritional and biological functions, which are extensively used in functional food industries. Phospholipase D (PLD)-mediated transphosphatidylation of phosphatidylcholine (PC) or DHA-PC with l-serine, is an effective method for PS and DHA-PS preparation. However, because of the hydrolysis activity of PLD, PC and DHA-PC would be converted to the undesirable byproduct, phosphatidic acid (PA) and DHA-PA. In this study, a novel phospholipase D (PLD a2 ) was firstly cloned from Acinetobacter radioresistens a2 with high transphosphatidylation activity and no hydrolysis activity. In the PLD-catalyzed synthesis process (12h), both the transphosphatidylation conversion rate and selectivity of PS and DHA-PS were about 100%, which is the only PLD enzyme reported with this superiority up till now. In comparison with the majority of other known PLDs, PLD a2 exerted the highest activity at neutral pH, and it was stable from pH 4.0 to pH 9.0. In addition, PLD a2 had excellent thermal stability, with an optimum reaction temperature of 40°C and keeping more than 80% activity from 20°C to 60°C. The high catalytic selectivity mechanism of PLD a2 was explained by utilizing homology modeling, two-step docking, and binding energy and conformation analysis. PLD a2 ensured a stable supply of the biocatalyst with its most preponderant transphosphatidylation activity and PS selectivity, and had great potential in phospholipids industrial production. Copyright © 2017 Elsevier B.V. All rights reserved.
Eisele, Thomas P; Silumbe, Kafula; Finn, Timothy; Chalwe, Victor; Kamuliwo, Mukalwa; Hamainza, Busiku; Moonga, Hawela; Bennett, Adam; Yukich, Josh; Keating, Joseph; Steketee, Richard W; Miller, John M
2015-08-13
Mass drug administration (MDA) and focal MDA (fMDA) using dihydroartemisinin plus piperaquine (DHAp), represent two strategies to maximize the use of existing information to achieve greater clearance of human infection and reduce the parasite reservoir, and provide longer chemoprophylactic protection against new infections. The primary aim of this study is to quantify the relative effectiveness of MDA and fMDA with DHAp against no mass treatment (standard of care) for reducing Plasmodium falciparum prevalence and incidence. The study will be conducted along Lake Kariba in Southern Province, Zambia; an area of low to moderate malaria transmission and high coverage of vector control. A community randomized controlled trial (CRCT) of 60 health facility catchment areas (HFCAs) will be used to evaluate the impact of two rounds of MDA and fMDA interventions, relative to a control of no mass treatment, stratified by high and low transmission. Community residents in MDA HFCAs will be treated with DHAp at the end of the dry season (round one: November to December 2014) and the beginning of the rainy season (round two: February to March 2015). Community residents in fMDA HFCAs will be tested during the same two rounds for malaria parasites with a rapid diagnostic test; all positive individuals and all individuals living in their household will be treated with DHAp. Primary outcomes include malaria parasite prevalence (n = 5,640 children aged one month to under five-years-old), as measured by pre- and post-surveys, and malaria parasite infection incidence (n = 2,250 person-years among individuals aged three months and older), as measured by a monthly longitudinal cohort. The study is powered to detect approximately a 50 % relative reduction in these outcomes between each intervention group versus the control. Strengths of this trial include: a robust study design (CRCT); cross-sectional parasite surveys as well as a longitudinal cohort; and stratification of high and low transmission areas. Primary limitations include: statistical power to detect only a 50 % reduction in primary outcomes within high and low transmission strata; potential for contamination; and potential for misclassification of exposure. Identifier: Clinicaltrials.gov: NCT02329301 . Registration date: 30 December 2014.
St-Jean, Miguel; Blonski, Casimir; Sygusch, Jurgen
2009-06-02
Fructose-1,6-bisphosphate muscle aldolase is an essential glycolytic enzyme that catalyzes reversible carbon-carbon bond formation by cleaving fructose 1,6-bisphosphate to yield dihydroxyacetone phosphate (DHAP) and d-glyceraldehyde phosphate. To elucidate the mechanistic role of conserved amino acid Asp-33, Asn-33 and Ser-33 mutants were examined by kinetic and structural analyses. The mutations significantly compromised enzymatic activity and carbanion oxidation in presence of DHAP. Detailed structural analysis demonstrated that, like native crystals, Asp-33 mutant crystals, soaked in DHAP solutions, trapped Schiff base-derived intermediates covalently attached to Lys-229. The mutant structures, however, exhibited an abridged conformational change with the helical region (34-65) flanking the active site as well as pK(a) reductions and increased side chain disorder by central lysine residues, Lys-107 and Lys-146. These changes directly affect their interaction with the C-terminal Tyr-363, consistent with the absence of active site binding by the C-terminal region in the presence of phosphate. Lys-146 pK(a) reduction and side chain disorder would further compromise charge stabilization during C-C bond cleavage and proton transfer during enamine formation. These mechanistic impediments explain diminished catalytic activity and a reduced level of carbanion oxidation and are consistent with rate-determining proton transfer observed in the Asn-33 mutant. Asp-33 reduces the entropic cost and augments the enthalpic gain during catalysis by rigidifying Lys-107 and Lys-146, stabilizing their protonated forms, and promoting a conformational change triggered by substrate or obligate product binding, which lower kinetic barriers in C-C bond cleavage and Schiff base-enamine interconversion.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-29
... to facilitate on-going tracking and management of these services, leading to greater self-sufficiency... Congress. Comments Due Date: January 28, 2011. ADDRESSES: Interested persons are invited to submit comments... SYSTEM NAME: Efforts to Outcome Case Management Tracking System for DHAP-Ike. SYSTEM LOCATION: Baltimore...
Yang, Jiangang; Li, Jitao; Men, Yan; Zhu, Yueming; Zhang, Ying; Ma, Yanhe
2015-01-01
The property of loose stereochemical control at aldol products from aldolases helped to synthesize multiple polyhydroxylated compounds with nonnatural stereoconfiguration. In this study, we discovered for the first time that some fructose 1,6-diphosphate aldolases (FruA) and tagatose 1,6-diphosphate (TagA) aldolases lost their strict stereoselectivity when using l-glyceraldehyde and synthesized not only l-sorbose but also a high proportion of l-psicose. Among the aldolases tested, TagA from Bacillus licheniformis (BGatY) showed the highest enzyme activity with l-glyceraldehyde. Subsequently, a “one-pot” reaction based on BGatY and fructose-1-phosphatase (YqaB) generated 378 mg/liter l-psicose and 199 mg/liter l-sorbose from dihydroxyacetone-phosphate (DHAP) and l-glyceraldehyde. Because of the high cost and instability of DHAP, a microbial fermentation strategy was used further to produce l-sorbose/l-psicose from glucose and l-glyceraldehyde, in which DHAP was obtained from glucose through the glycolytic pathway, and some recombination pathways based on FruA or TagA and YqaB were constructed in Escherichia coli and Corynebacterium glutamicum strains. After evaluation of different host cells and combinations of FruA or TagA with YqaB and optimization of gene expression, recombinant C. glutamicum strain WT(pXFTY) was selected and produced 2.53 g/liter total ketoses, with a yield of 0.50 g/g l-glyceraldehyde. Moreover, deletion of gene cgl0331, encoding the Zn-dependent alcohol dehydrogenase in C. glutamicum, was confirmed for the first time to significantly decrease conversion of l-glyceraldehyde to glycerol and to increase yield of target products. Finally, fed-batch culture of strain SY14(pXFTY) produced 3.5 g/liter l-sorbose and 2.3 g/liter l-psicose, with a yield of 0.61 g/g l-glyceraldehyde. This microbial fermentation strategy also could be applied to efficiently synthesize other l-sugars. PMID:25888171
Drosophila Courtship Conditioning As a Measure of Learning and Memory.
Koemans, Tom S; Oppitz, Cornelia; Donders, Rogier A T; van Bokhoven, Hans; Schenck, Annette; Keleman, Krystyna; Kramer, Jamie M
2017-06-05
Many insights into the molecular mechanisms underlying learning and memory have been elucidated through the use of simple behavioral assays in model organisms such as the fruit fly, Drosophila melanogaster. Drosophila is useful for understanding the basic neurobiology underlying cognitive deficits resulting from mutations in genes associated with human cognitive disorders, such as intellectual disability (ID) and autism. This work describes a methodology for testing learning and memory using a classic paradigm in Drosophila known as courtship conditioning. Male flies court females using a distinct pattern of easily recognizable behaviors. Premated females are not receptive to mating and will reject the male's copulation attempts. In response to this rejection, male flies reduce their courtship behavior. This learned reduction in courtship behavior is measured over time, serving as an indicator of learning and memory. The basic numerical output of this assay is the courtship index (CI), which is defined as the percentage of time that a male spends courting during a 10 min interval. The learning index (LI) is the relative reduction of CI in flies that have been exposed to a premated female compared to naïve flies with no previous social encounters. For the statistical comparison of LIs between genotypes, a randomization test with bootstrapping is used. To illustrate how the assay can be used to address the role of a gene relating to learning and memory, the pan-neuronal knockdown of Dihydroxyacetone phosphate acyltransferase (Dhap-at) was characterized here. The human ortholog of Dhap-at, glyceronephosphate O-acyltransferase (GNPT), is involved in rhizomelic chondrodysplasia punctata type 2, an autosomal-recessive syndrome characterized by severe ID. Using the courtship conditioning assay, it was determined that Dhap-at is required for long-term memory, but not for short-term memory. This result serves as a basis for further investigation of the underlying molecular mechanisms.
Kinetic mechanism of L-α-glycerophosphate oxidase from Mycoplasma pneumoniae.
Maenpuen, Somchart; Watthaisong, Pratchaya; Supon, Pacharee; Sucharitakul, Jeerus; Parsonage, Derek; Karplus, P Andrew; Claiborne, Al; Chaiyen, Pimchai
2015-08-01
L-α-glycerophosphate oxidase is an FAD-dependent enzyme that catalyzes the oxidation of L-α-glycerophosphate (Glp) by molecular oxygen to generate dihydroxyacetone phosphate (DHAP) and hydrogen peroxide (H2O2). The catalytic properties of recombinant His6-GlpO from Mycoplasma pneumoniae (His6-MpGlpO) were investigated through transient and steady-state kinetics and ligand binding studies. The results indicate that the reaction mechanism of His6-MpGlpO follows a ping-pong model. Double-mixing mode stopped-flow experiments show that, after flavin-mediated substrate oxidation, DHAP leaves rapidly prior to the oxygen reaction. The values determined for the individual rate constants and kcat (4.2 s(-1) at 4 °C), in addition to the finding that H2 O2 binds to the oxidized enzyme, suggest that H2O2 release is the rate-limiting step for the overall reaction. The results indicate that His6 -MpGlpO contains mixed populations of fast- and slow-reacting species. It is predominantly the fast-reacting species that participates in turnover. In contrast to other GlpO enzymes previously described, His6-MpGlpO is able to catalyze the reverse reaction of reduced enzyme and DHAP. This result may be explained by the standard reduction potential value of His6-MpGlpO (-167 ± 1 mV), which is lower than those of GlpO from other species. We found that D,L-glyceraldehyde 3-phosphate (GAP) may be used as a substrate in the His6-MpGlpO reaction, although it exhibited an approximately 100-fold lower kcat value in comparison with the reaction of Glp. These results also imply involvement of GlpO in glycolysis, as well as in lipid and glycerol metabolism. The kinetic models and distinctive properties of His6-MpGlpO reported here should be useful for future drug development against Mycoplasma pneumoniae infection. © 2015 FEBS.
Zhai, Xiang; Go, Maybelle K; O'Donoghue, AnnMarie C; Amyes, Tina L; Pegan, Scott D; Wang, Yan; Loria, J Patrick; Mesecar, Andrew D; Richard, John P
2014-06-03
Two mutations of the phosphodianion gripper loop in chicken muscle triosephosphate isomerase (cTIM) were examined: (1) the loop deletion mutant (LDM) formed by removal of residues 170-173 [Pompliano, D. L., et al. (1990) Biochemistry 29, 3186-3194] and (2) the loop 6 replacement mutant (L6RM), in which the N-terminal hinge sequence of TIM from eukaryotes, 166-PXW-168 (X = L or V), is replaced by the sequence from archaea, 166-PPE-168. The X-ray crystal structure of the L6RM shows a large displacement of the side chain of E168 from that for W168 in wild-type cTIM. Solution nuclear magnetic resonance data show that the L6RM results in significant chemical shift changes in loop 6 and surrounding regions, and that the binding of glycerol 3-phosphate (G3P) results in chemical shift changes for nuclei at the active site of the L6RM that are smaller than those of wild-type cTIM. Interactions with loop 6 of the L6RM stabilize the enediolate intermediate toward the elimination reaction catalyzed by the LDM. The LDM and L6RM result in 800000- and 23000-fold decreases, respectively, in kcat/Km for isomerization of GAP. Saturation of the LDM, but not the L6RM, by substrate and inhibitor phosphoglycolate is detected by steady-state kinetic analyses. We propose, on the basis of a comparison of X-ray crystal structures for wild-type TIM and the L6RM, that ligands bind weakly to the L6RM because a large fraction of the ligand binding energy is utilized to overcome destabilizing electrostatic interactions between the side chains of E168 and E129 that are predicted to develop in the loop-closed enzyme. Similar normalized yields of DHAP, d-DHAP, and d-GAP are formed in LDM- and L6RM-catalyzed reactions of GAP in D2O. The smaller normalized 12-13% yield of DHAP and d-DHAP observed for the mutant cTIM-catalyzed reactions compared with the 79% yield of these products for wild-type cTIM suggests that these mutations impair the transfer of a proton from O-2 to O-1 at the initial enediolate phosphate intermediate. No products are detected for the LDM-catalyzed isomerization reactions in D2O of [1-(13)C]GA and HPi, but the L6RM-catalyzed reaction in the presence of 0.020 M dianion gives a 2% yield of the isomerization product [2-(13)C,2-(2)H]GA.
Yang, Jiangang; Zhu, Yueming; Men, Yan; Sun, Shangshang; Zeng, Yan; Zhang, Ying; Sun, Yuanxia; Ma, Yanhe
2016-12-21
Rare sugars are valuable natural products widely used in pharmaceutical and food industries. In this study, we expected to synthesize rare ketoses from abundant glycerol using dihydroxyacetone phosphate (DHAP)-dependent aldolases. First, a new glycerol assimilation pathway was constructed to synthesize DHAP. The enzymes which convert glycerol to 3-hydroxypropionaldehyde and l-glyceraldehyde were selected, and their corresponding aldehyde synthesis pathways were constructed in vivo. Four aldol pathways based on different aldolases and phosphorylase were gathered. Next, three pathways were assembled and the resulting strains synthesized 5-deoxypsicose, 5-deoxysorbose, and 5-deoxyfructose from glucose and glycerol and produce l-fructose, l-tagatose, l-sorbose, and l-psicose with glycerol as the only carbon source. To achieve higher product titer and yield, the recombinant strains were further engineered and fermentation conditions were optimized. Fed-batch culture of engineered strains obtained 38.1 g/L 5-deoxypsicose with a yield of 0.91 ± 0.04 mol product per mol of glycerol and synthesized 20.8 g/L l-fructose, 10.3 g/L l-tagatose, 1.2 g/L l-sorbose, and 0.95 g/L l-psicose.
Islam, Zia-Ul; Klein, Mathias; Aßkamp, Maximilian R; Ødum, Anders S R; Nevoigt, Elke
2017-11-01
Compared to sugars, a major advantage of using glycerol as a feedstock for industrial bioprocesses is the fact that this molecule is more reduced than sugars. A compound whose biotechnological production might greatly profit from the substrate's higher reducing power is 1,2-propanediol (1,2-PDO). Here we present a novel metabolic engineering approach to produce 1,2-PDO from glycerol in S. cerevisiae. Apart from implementing the heterologous methylglyoxal (MG) pathway for 1,2-PDO formation from dihydroxyacetone phosphate (DHAP) and expressing a heterologous glycerol facilitator, the employed genetic modifications included the replacement of the native FAD-dependent glycerol catabolic pathway by the 'DHA pathway' for delivery of cytosolic NADH and the reduction of triosephosphate isomerase (TPI) activity for increased precursor (DHAP) supply. The choice of the medium had a crucial impact on both the strength of the metabolic switch towards fermentation in general (as indicated by the production of ethanol and 1,2-PDO) and on the ratio at which these two fermentation products were formed. For example, virtually no 1,2-PDO but only ethanol was formed in synthetic glycerol medium with urea as the nitrogen source. When nutrient-limited complex YG medium was used, significant amounts of 1,2-PDO were formed and it became obvious that the concerted supply of NADH and DHAP are essential for boosting 1,2-PDO production. Additionally, optimizing the flux into the MG pathway improved 1,2-PDO formation at the expense of ethanol. Cultivation of the best-performing strain in YG medium and a controlled bioreactor set-up resulted in a maximum titer of > 4gL -1 1,2-PDO which, to the best of our knowledge, has been the highest titer of 1,2-PDO obtained in yeast so far. Surprisingly, significant 1,2-PDO production was also obtained in synthetic glycerol medium after changing the nitrogen source towards ammonium sulfate and adding a buffer. Copyright © 2017 International Metabolic Engineering Society. Published by Elsevier Inc. All rights reserved.
McCarthy, Jeanne; Gopal, Ajay K
2009-04-01
Anthracycline-based chemotherapy is the cornerstone of modern curative regimens for aggressive lymphomas; however, these drugs cannot be safely administered in the setting of severe hepatic dysfunction. Alternative regimens for this setting are required. We describe 2 patients with newly diagnosed advanced aggressive lymphoma (diffuse large B-cell lymphoma [DLBCL] and classic Hodgkin lymphoma [HL]) presenting with severe hepatic dysfunction with hyperbilirubinemia (4.3-13.2 mg/dL). Because of the inability to safely administer unattenuated doses of anthracycline-based regimens, dexamethasone, high-dose cytarabine, and cisplatin (DHAP) was used at full doses (along with rituximab for the DLBCL patient) until hepatic function normalized (1-5 cycles). The treatment was then converted to R-CHOP (rituximab/cyclophosphamide/ doxorubicin/vincristine/prednisone) and ABVD (doxorubicin/bleomycin/vinblastine/dacarbazine) for the DLBCL and HL patient, respectively, to complete therapy. The patients had a partial remission and complete remission, respectively. These data suggest that DHAP is a safe and effective regimen that can be used without dose modification as part of initial therapy in the setting of aggressive lymphoma and hepatic failure. The literature on the use of treatment regimens for aggressive lymphoma in the setting of hepatic dysfunction is reviewed.
Tertiary Oximes on Brain Acetylcholinesterase and Central Excitatory Effects of Nerve Agents
2012-01-01
5 test doses of the oxime. Animals were euthanized 45 min after oxime treatment when blood and target tissues were collected. AChE activity was...the ability of MINA and DHAP to block or terminate nerve agent-induced electroencephalographic (EEG) seizure activity was evaluated. Animals...instrumented to record brain EEG activity were challenged with a seizure-inducing dose (2.0 x LD50) of GB, GF, or VX, and oxime was administered one min
Cai, Ma; He, Li-Hong; Yu, Tu-Yuan
2013-01-01
Glycerol is an important osmotically compatible solute in Dunaliella. Glycerol-3-phosphate dehydrogenase (G3PDH) is a key enzyme in the pathway of glycerol synthesis, which converts dihydroxyacetone phosphate (DHAP) to glycerol-3-phosphate. Generally, the glycerol-DHAP cycle pathway, which is driven by G3PDH, is considered as the rate-limiting enzyme to regulate the glycerol level under osmotic shocks. Considering the peculiarity in osmoregulation, the cDNA of a NAD+-dependent G3PDH was isolated from D. salina using RACE and RT-PCR approaches in this study. Results indicated that the length of the cDNA sequence of G3PDH was 2,100 bp encoding a 699 amino acid deduced polypeptide whose computational molecular weight was 76.6 kDa. Conserved domain analysis revealed that the G3PDH protein has two independent functional domains, SerB and G3PDH domains. It was predicted that the G3PDH was a nonsecretory protein and may be located in the chloroplast of D. salina. Phylogenetic analysis demonstrated that the D. salina G3PDH had a closer relationship with the G3PDHs from the Dunaliella genus than with those from other species. In addition, the cDNA was subsequently subcloned in the pET-32a(+) vector and was transformed into E. coli strain BL21 (DE3), a expression protein with 100 kDa was identified, which was consistent with the theoretical value. PMID:23626797
Active site loop dynamics of a class IIa fructose 1,6-bisphosphate aldolase from M. tuberculosis
Pegan, Scott D.; Rukseree, Kamolchanok; Capodagli, Glenn C.; Baker, Erica A; Krasnykh, Olga; Franzblau, Scott G; Mesecar, Andrew D
2014-01-01
Class II fructose 1,6-bisphosphate aldolases (FBA; E.C. 4.1.2.13) comprise one of two families of aldolases. Instead of forming a Schiff-base intermediate using an ε-amino group of a lysine side chain, class II FBAs utilize Zn(II) to stabilize a proposed hydroxyenolate intermediate (HEI) in the reversible cleavage of fructose 1,6-bisphosphate forming glyceraldehyde 3-phosphate and dihydroxyacetone phosphate (DHAP). As class II FBAs has been shown to be essential in pathogenic bacteria, focus has been placed on these enzymes as potential antibacterial targets. Although structural studies on class II FBAs from Mycobacterium tuberculosis (MtFBA), other bacteria and protozoa have been reported, the structure of the active site loop responsible for catalyzing the protonation/deprotonation steps of the reaction for class II FBAs has not yet been observed. We therefore utilized the potent class II FBA inhibitor phosphoglycolohydroxamate (PGH) as a mimic of the HEI/DHAP bound form of the enzyme and determined the X-ray structure of MtFBA-PGH complex to 1.58 Å. Remarkably, we are able to observe well-defined electron density for the previously elusive active site loop of MtFBA trapped in a catalytically competent orientation. Utilization of this structural information plus site-directed mutagenesis and kinetic studies conducted on a series of residues within the active-site loop revealed that E169 facilitates a water mediated deprotonation/protonation step of the MtFBA reaction mechanism. Also, secondary isotope effects on MtFBA and catalytically relevant mutants were used to probe the effect of loop flexibility on catalytic efficiency. Additionally, we also reveal the structure of MtFBA in its holoenzyme form. PMID:23298222
Pegan, Scott D; Rukseree, Kamolchanok; Capodagli, Glenn C; Baker, Erica A; Krasnykh, Olga; Franzblau, Scott G; Mesecar, Andrew D
2013-02-05
Class II fructose 1,6-bisphosphate aldolases (FBAs, EC 4.1.2.13) comprise one of two families of aldolases. Instead of forming a Schiff base intermediate using an ε-amino group of a lysine side chain, class II FBAs utilize Zn(II) to stabilize a proposed hydroxyenolate intermediate (HEI) in the reversible cleavage of fructose 1,6-bisphosphate, forming glyceraldehyde 3-phosphate and dihydroxyacetone phosphate (DHAP). As class II FBAs have been shown to be essential in pathogenic bacteria, focus has been placed on these enzymes as potential antibacterial targets. Although structural studies of class II FBAs from Mycobacterium tuberculosis (MtFBA), other bacteria, and protozoa have been reported, the structure of the active site loop responsible for catalyzing the protonation-deprotonation steps of the reaction for class II FBAs has not yet been observed. We therefore utilized the potent class II FBA inhibitor phosphoglycolohydroxamate (PGH) as a mimic of the HEI- and DHAP-bound form of the enzyme and determined the X-ray structure of the MtFBA-PGH complex to 1.58 Å. Remarkably, we are able to observe well-defined electron density for the previously elusive active site loop of MtFBA trapped in a catalytically competent orientation. Utilization of this structural information and site-directed mutagenesis and kinetic studies conducted on a series of residues within the active site loop revealed that E169 facilitates a water-mediated deprotonation-protonation step of the MtFBA reaction mechanism. Also, solvent isotope effects on MtFBA and catalytically relevant mutants were used to probe the effect of loop flexibility on catalytic efficiency. Additionally, we also reveal the structure of MtFBA in its holoenzyme form.
Pegan, Scott D.; Rukseree, Kamolchanok; Franzblau, Scott G.; Mesecar, Andrew D.
2009-01-01
Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), currently infects one third of the world’s population in its latent form. The emergence of multidrug resistant strains, MDR-TB and XDR-TB has highlighted the need for new pharmacological targets within M. tuberculosis. The Class IIa fructose 1,6-bisphosphate aldolase (FBA) enzyme from M. tuberculosis (MtFBA) has been proposed as one such target since its upregulated in latent TB. Since the structure of MtFBA had not been determined and since there was little information available on its reaction mechanism, we sought to determine the X-ray structure of MtFBA in complex with its substrates. By lowering the pH of the enzyme in the crystalline state, we were able to determine a series of high-resolution X-ray structures of MtFBA bound to dihydroxyacetonephosphate (DHAP), glyceraldehyde-3-phosphate (G3P), and fructose 1,6-bisphosphate (FBP) at 1.5 Å, 2.1 Å, and 1.3 Å respectively. Through these structures it was discovered that MtFBA belongs to a novel tetrameric class of the type IIa FBAs. The molecular details at the interface of the tetramer revealed important information for being able to better predict the quaternary structures among the FBAs based on their primary sequences. These X-ray structures also provide interesting and new details on the reaction mechanism of class II FBAs. Not only were the substrates and products observed in geometries poised for catalysis, but unexpectedly the hydroxyl enolate intermediate of DHAP was also captured and resolved structurally. These concise new details provide a better understanding of the reaction mechanisms for FBAs in general and provide a structural basis for inhibitor design efforts aimed at this class of enzymes. PMID:19167403
Yang, Jiangang; Zhu, Yueming; Li, Jitao; Men, Yan; Sun, Yuanxia; Ma, Yanhe
2015-01-01
Rare sugars have various known biological functions and potential for applications in pharmaceutical, cosmetics, and food industries. Here we designed and constructed a recombination pathway in Corynebacterium glutamicum, in which dihydroxyacetone phosphate (DHAP), an intermediate of the glycolytic pathway, and a variety of aldehydes were condensed to synthesize rare ketoses sequentially by rhamnulose-1-phosphate aldolase (RhaD) and fructose-1-phosphatase (YqaB) obtained from Escherichia coli. A wild-type strain harboring this artificial pathway had the ability to produce D-sorbose and D-psicose using D-glyceraldehyde and glucose as the substrates. The tpi gene, encoding triose phosphate isomerase was further deleted, and the concentration of DHAP increased to nearly 20-fold relative to that of the wild-type. After additional optimization of expression levels from rhaD and yqaB genes and of the fermentation conditions, the engineered strain SY6(pVRTY) exhibited preferable performance for rare ketoses production. Its yield increased to 0.59 mol/mol D-glyceraldehyde from 0.33 mol/mol D-glyceraldehyde and productivity to 2.35 g/L h from 0.58 g/L h. Moreover, this strain accumulated 19.5 g/L of D-sorbose and 13.4 g/L of D-psicose using a fed-batch culture mode under the optimal conditions. In addition, it was verified that the strain SY6(pVRTY) meanwhile had the ability to synthesize C4, C5, C6, and C7 rare ketoses when a range of representative achiral and homochiral aldehydes were applied as the substrates. Therefore, the platform strain exhibited the potential for microbial production of rare ketoses and deoxysugars. © 2014 Wiley Periodicals, Inc.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pegan, Scott D.; Rukseree, Kamolchanok; Capodagli, Glenn C.
The class II fructose 1,6-bisphosphate aldolases (FBAs, EC 4.1.2.13) comprises one of two families of aldolases. Instead of forming a Schiff base intermediate using an ε-amino group of a lysine side chain, class II FBAs utilize Zn(II) to stabilize a proposed hydroxyenolate intermediate (HEI) in the reversible cleavage of fructose 1,6-bisphosphate, forming glyceraldehyde 3-phosphate and dihydroxyacetone phosphate (DHAP). As class II FBAs have been shown to be essential in pathogenic bacteria, focus has been placed on these enzymes as potential antibacterial targets. Although structural studies of class II FBAs from Mycobacterium tuberculosis (MtFBA), other bacteria, and protozoa have been reported,more » the structure of the active site loop responsible for catalyzing the protonation–deprotonation steps of the reaction for class II FBAs has not yet been observed. We therefore utilized the potent class II FBA inhibitor phosphoglycolohydroxamate (PGH) as a mimic of the HEI- and DHAP-bound form of the enzyme and determined the X-ray structure of the MtFBA–PGH complex to 1.58 Å. Remarkably, we are able to observe well-defined electron density for the previously elusive active site loop of MtFBA trapped in a catalytically competent orientation. Utilization of this structural information and site-directed mutagenesis and kinetic studies conducted on a series of residues within the active site loop revealed that E169 facilitates a water-mediated deprotonation–protonation step of the MtFBA reaction mechanism. Furthermore, solvent isotope effects on MtFBA and catalytically relevant mutants were used to probe the effect of loop flexibility on catalytic efficiency. Additionally, we also reveal the structure of MtFBA in its holoenzyme form.« less
In vitro and in vivo tests of PLA/d-HAp nanocomposite
NASA Astrophysics Data System (ADS)
Thom Nguyen, Thi; Hoang, Thai; Mao Can, Van; Son Ho, Anh; Hai Nguyen, Song; Thu Trang Nguyen, Thi; Pham, Thi Nam; Phuong Nguyen, Thu; Le Hien Nguyen, Thi; Thanh Dinh Thi, Mai
2017-12-01
The bioactivity of the PLA/d-HAp nanocomposite with 30 wt.% d-HAp was evaluated by in vitro tests and indicated that after 7 immersion days in SBF solution, PLA amorphous part was hydrolyzed and PLA crystal part was remained. The formation of apatite on the surface of the material was observed. The in vivo test results of PLA/d-HAp nanocomposite (70/30 wt/wt) on femur of dogs displayed that 3 months after grafting, the materials did not induce any osteitis, osteomyelitis or structural abnormalities. The histological and x-ray image demonstrated a growth of the bone into the material area, while osteitis and osteomyelitis were not observed.
Low-cost synthesis and physical characterization of thieno[3,4-c]pyrrole-4,6-dione-based polymers.
Berrouard, Philippe; Dufresne, Stéphane; Pron, Agnieszka; Veilleux, Justine; Leclerc, Mario
2012-09-21
The improved synthesis of thieno[3,4-c]pyrrole-4,6-dione (TPD) monomers, including Gewald thiophene ring formation, a Sandmeyer-type reaction, and neat condensation with an amine, is presented. This protocol enables faster, cheaper, and more efficient preparation of TPD units in comparison to traditional methods. Furthermore, a series of TPD homo- and pseudohomopolymers bearing various alkyl chains was synthesized via a direct heteroarylation polymerization (DHAP) procedure. UV-visible absorption and powder X-ray diffraction measurements revealed the relationship between the ratio of branched to linear alkyl chains and the optoelectronic properties of the polymers as well as their packing in the solid state.
Tessoulin, B; Thomare, P; Delande, E; Moynard, J; Gastinne, T; Moreau, A; Bossard, C; Mahé, B; Blin, N; Dubruille, V; Touzeau, C; Boudreault, J S; Perrin, F; Lok, A; Guillaume, T; Garnier, A; Peterlin, P; Gallas, P; Chevallier, P; Moreau, P; Le Gouill, Steven
2017-06-01
The DHAP regimen (high-dose cytarabine in combination with dexamethasone and cisplatin) with or without rituximab (DHAP+/-R) is one of the most common regimens in daily practice. It is considered the standard treatment for relapse or refractory Hodgkin's and non-Hodgkin's lymphoma (NHL). Cisplatin nephrotoxicity is a major concern, and other platinum compounds are being tried. We performed a monocentric retrospective analysis to evaluate the use of carboplatin, so-called DHAC+/-R regimen. The purpose was to assess the toxicity of the DHAC+/-R regimen in real-life. The Dexamethasone, Cytarabine, Carboplatin (DHAC) regimen consisted of carboplatin AUC = 5 mg/ml/min (targeted area under the curve with Calvert's formula) on day 1, cytarabine 2 g/m 2 twice a day on day 2 and IV dexamethasone 40 mg from days 1 to 4. Rituximab was administrated at 375 mg/m 2 on day 1 for CD20+ NHL. The interval between courses was 21 days. During the period considered, 199 patients received DHAC+/-R. For the entire cohort, median follow-up is 24 months (range, 2-82), median OS is not reached (NR), estimated 2-year OS is 75% (95% CI, 69-83) and median progression-free survival (PFS) is 46 months (95% CI, 22-NA). Of 144 patients scheduled for autologous stem cell transplantation (ASCT), 102 (71%, NA = 2) were in response after DHAC+/-R and all except 4 underwent ASCT. Grade ≥ 3 haematological toxicities were mainly thrombocytopenia (n = 101) and anaemia (n = 95). Grade ≥ 3 neutropenia occurred in 10 patients. No grade ≥ 3 renal and one grade 3 neurological toxicity were reported. DHAC+/-R is feasible in daily practice, provides good response rates and jeopardises neither stem cell collection nor ASCT.
Code of Federal Regulations, 2011 CFR
2011-01-01
... assistance, program assistance, and marketing. 455.122 Section 455.122 Energy DEPARTMENT OF ENERGY ENERGY... for State grants for technical assistance, program assistance, and marketing. Applications from States for financial assistance for technical assistance programs, program assistance, and marketing shall...
1990-05-31
hbeter at Arecibo. shbing teperral evolution of spotita diattlrbutio. (Barrnhardt at al, 1988). ftAStdA LOC WEf SP2CTh 5VF £NHAIJCRV DOWIr FUTO C...astt tubsim. Ahmy, Phpe. Iubidt. 31,73(1669) (1631 LM.Dsgtyue, R.SJqduv. Ojieolmv, V.DA-dhap, mad Vlmhuhebm, O"fm.4ai msAl Lmwmm telbahaci leo J1.h P...aestual gas devaity drop rapid" as the beam expands, When the neutral dentsity Is low, so bIto a robability of knsazanin. Them, If CV bn to occur. It
34 CFR 477.1 - What is the State Program Analysis Assistance and Policy Studies Program?
Code of Federal Regulations, 2011 CFR
2011-07-01
... ANALYSIS ASSISTANCE AND POLICY STUDIES PROGRAM General § 477.1 What is the State Program Analysis Assistance and Policy Studies Program? The State Program Analysis Assistance and Policy Studies Program... 34 Education 3 2011-07-01 2011-07-01 false What is the State Program Analysis Assistance and...
34 CFR 477.1 - What is the State Program Analysis Assistance and Policy Studies Program?
Code of Federal Regulations, 2010 CFR
2010-07-01
... ANALYSIS ASSISTANCE AND POLICY STUDIES PROGRAM General § 477.1 What is the State Program Analysis Assistance and Policy Studies Program? The State Program Analysis Assistance and Policy Studies Program... 34 Education 3 2010-07-01 2010-07-01 false What is the State Program Analysis Assistance and...
31 CFR 205.5 - What are the thresholds for major Federal assistance programs?
Code of Federal Regulations, 2010 CFR
2010-07-01
... assistance programs? (a) Table A of this section defines major Federal assistance programs based on the... locate the appropriate row in Column A based upon the total amount of Federal assistance received. In... Federal Assistance Program means any Federal assistance program that exceed these levels: Between zero and...
75 FR 13521 - Centers for Independent Living Program-Training and Technical Assistance
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-22
... DEPARTMENT OF EDUCATION Centers for Independent Living Program--Training and Technical Assistance... for Independent Living Program--Training and Technical Assistance (CIL-TA program). The Assistant... appropriated for the CIL program to provide training and technical assistance to CILs, agencies eligible to...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-14
... Program, Disaster Assistance Programs, Marketing Assistance Loans and Loan Deficiency Payments Program... Disaster Program (LFP), the Supplemental Revenue Assistance Payments Program (SURE) and the Marketing... losses, unless the loss has already been reported for the Noninsured Crop Disaster Assistance Program...
Homeowners Assistance Program (HAP)
1992-06-26
Assistance Program (HAP) References: (a) DoD Instruction 4165.50, "Administration and Operation of the Homeowners Assistance Program ," February 11, 1972...hereby canceled) (b) DoD Directive 5100.54, "Homeowners Assistance Program ," December 29, 1967 (hereby canceled) (c) Section 1013 of Public Law 89-754...Defense Program and annual budgets for the Homeowners Assistance Fund, Defense. m. Publish regulations and forms, subject to review by . the Assistant
34 CFR 379.42 - What are the special requirements pertaining to the Client Assistance Program?
Code of Federal Regulations, 2010 CFR
2010-07-01
... Client Assistance Program? 379.42 Section 379.42 Education Regulations of the Offices of the Department... requirements pertaining to the Client Assistance Program? Each grantee under a program covered by this part... availability and purposes of the State's Client Assistance Program, including information on seeking assistance...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-19
... Awards for the Assisted Living Conversion Program; Fiscal Year 2009 AGENCY: Office of the Assistant... funding under the Notice of Funding Availability (NOFA) for the Assisted Living Conversion Program (ALCP... for this program is 14.314. The Assisted Living Conversion Program is designed to provide funds to...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-15
... Awards for the Assisted Living Conversion Program Fiscal Year 2012 AGENCY: Office of the Assistant... funding under the Notice of Funding Availability (NOFA) for the Assisted Living Conversion Program (ALCP... for this program is 14.314. The Assisted Living Conversion Program is designed to provide funds to...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-25
... Awards for the Assisted Living Conversion Program; Fiscal Year 2010 AGENCY: Office of the Assistant... competition for funding under the Notice of Funding Availability (NOFA) for the Assisted Living Conversion... Assistance number for this program is 14.314. The Assisted Living Conversion Program is designed to provide...
49 CFR 266.3 - Rail Service Assistance Program.
Code of Federal Regulations, 2010 CFR
2010-10-01
... construction assistance; (6) Planning assistance; and (7) Program operations assistance. (b) Special limitations on planning assistance and program operation assistance. (1) A State is eligible to receive up to $100,000, or 5 percent of its entitlement, whichever is greater, as planning assistance; and (2) A...
25 CFR 170.161 - What is the Indian Local Technical Assistance Program?
Code of Federal Regulations, 2010 CFR
2010-04-01
... 25 Indians 1 2010-04-01 2010-04-01 false What is the Indian Local Technical Assistance Program... Technical Assistance Program § 170.161 What is the Indian Local Technical Assistance Program? The Indian Local Technical Assistance Program (Indian LTAP) is authorized under 23 U.S.C. 504(b), and §§ 170.161...
Compendium of Programs to Assist the Transition
1993-02-01
Program Description The Interagency Placement Assistance Program (IPAP) offices maintain computerized listings of data on employees faced with...possible reduction in force (RIF) separations. Program Objective To provide placement assistance to employees faced with possible RIF separations by making... employees . 23 2/93 TRANSITION ASSISTANCE PROGRAM Short Name of Program TAP Program Description Begun in 1991, TAP is a joint program of
26 CFR 1.127-2 - Qualified educational assistance program.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 26 Internal Revenue 2 2011-04-01 2011-04-01 false Qualified educational assistance program. 1.127... Qualified educational assistance program. (a) In general. A qualified educational assistance program is a plan established and maintained by an employer under which the employer provides educational assistance...
31 CFR 205.1 - What Federal assistance programs are covered by this part?
Code of Federal Regulations, 2013 CFR
2013-07-01
...; and (2) All Federal program agencies, except the Tennessee Valley Authority (TVA) and its Federal assistance programs. (b) Only programs listed in the Catalog of Federal Domestic Assistance, as established... 31 Money and Finance:Treasury 2 2013-07-01 2013-07-01 false What Federal assistance programs are...
31 CFR 205.1 - What Federal assistance programs are covered by this part?
Code of Federal Regulations, 2011 CFR
2011-07-01
...; and (2) All Federal program agencies, except the Tennessee Valley Authority (TVA) and its Federal assistance programs. (b) Only programs listed in the Catalog of Federal Domestic Assistance, as established... 31 Money and Finance:Treasury 2 2011-07-01 2011-07-01 false What Federal assistance programs are...
31 CFR 205.1 - What Federal assistance programs are covered by this part?
Code of Federal Regulations, 2014 CFR
2014-07-01
...; and (2) All Federal program agencies, except the Tennessee Valley Authority (TVA) and its Federal assistance programs. (b) Only programs listed in the Catalog of Federal Domestic Assistance, as established... 31 Money and Finance: Treasury 2 2014-07-01 2014-07-01 false What Federal assistance programs are...
31 CFR 205.1 - What Federal assistance programs are covered by this part?
Code of Federal Regulations, 2012 CFR
2012-07-01
...; and (2) All Federal program agencies, except the Tennessee Valley Authority (TVA) and its Federal assistance programs. (b) Only programs listed in the Catalog of Federal Domestic Assistance, as established... 31 Money and Finance:Treasury 2 2012-07-01 2012-07-01 false What Federal assistance programs are...
Jaafar, Nardiah Rizwana; Littler, Dene; Beddoe, Travis; Rossjohn, Jamie; Illias, Rosli Md; Mahadi, Nor Muhammad; Mackeen, Mukram Mohamed; Murad, Abdul Munir Abdul; Abu Bakar, Farah Diba
2016-11-01
Fuculose-1-phosphate aldolase (FucA) catalyses the reversible cleavage of L-fuculose 1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. This enzyme from mesophiles and thermophiles has been extensively studied; however, there is no report on this enzyme from a psychrophile. In this study, the gene encoding FucA from Glaciozyma antarctica PI12 (GaFucA) was cloned and the enzyme was overexpressed in Escherichia coli, purified and crystallized. The tetrameric structure of GaFucA was determined to 1.34 Å resolution. The overall architecture of GaFucA and its catalytically essential histidine triad are highly conserved among other fuculose aldolases. Comparisons of structural features between GaFucA and its mesophilic and thermophilic homologues revealed that the enzyme has typical psychrophilic attributes, indicated by the presence of a high number of nonpolar residues at the surface and a lower number of arginine residues.
Code of Federal Regulations, 2010 CFR
2010-01-01
... Marketing § 455.90 Purpose. This subpart describes what constitutes a State program for technical assistance, program assistance, and marketing that may receive financial assistance under this part and sets forth the eligibility criteria for States to receive grants for technical assistance, program assistance, and marketing. ...
13 CFR 124.701 - What is the purpose of the 7(j) management and technical assistance program?
Code of Federal Regulations, 2010 CFR
2010-01-01
...) management and technical assistance program? 124.701 Section 124.701 Business Credit and Assistance SMALL...) Business Development Management and Technical Assistance Program § 124.701 What is the purpose of the 7(j) management and technical assistance program? Section 7(j)(1) of the Small Business Act, 15 U.S.C. 636(j)(1...
31 CFR 205.3 - What Federal assistance programs are subject to this subpart A?
Code of Federal Regulations, 2011 CFR
2011-07-01
... programs which: (1) Are listed in the Catalog of Federal Domestic Assistance; (2) Meet the funding... Federal assistance programs subject to subpart A if a State or Federal Program Agency fails to comply with... 31 Money and Finance:Treasury 2 2011-07-01 2011-07-01 false What Federal assistance programs are...
31 CFR 205.3 - What Federal assistance programs are subject to this subpart A?
Code of Federal Regulations, 2012 CFR
2012-07-01
... programs which: (1) Are listed in the Catalog of Federal Domestic Assistance; (2) Meet the funding... Federal assistance programs subject to subpart A if a State or Federal Program Agency fails to comply with... 31 Money and Finance:Treasury 2 2012-07-01 2012-07-01 false What Federal assistance programs are...
31 CFR 205.3 - What Federal assistance programs are subject to this subpart A?
Code of Federal Regulations, 2013 CFR
2013-07-01
... programs which: (1) Are listed in the Catalog of Federal Domestic Assistance; (2) Meet the funding... Federal assistance programs subject to subpart A if a State or Federal Program Agency fails to comply with... 31 Money and Finance:Treasury 2 2013-07-01 2013-07-01 false What Federal assistance programs are...
31 CFR 205.3 - What Federal assistance programs are subject to this subpart A?
Code of Federal Regulations, 2014 CFR
2014-07-01
... programs which: (1) Are listed in the Catalog of Federal Domestic Assistance; (2) Meet the funding... Federal assistance programs subject to subpart A if a State or Federal Program Agency fails to comply with... 31 Money and Finance: Treasury 2 2014-07-01 2014-07-01 false What Federal assistance programs are...
31 CFR 205.3 - What Federal assistance programs are subject to this subpart A?
Code of Federal Regulations, 2010 CFR
2010-07-01
... programs which: (1) Are listed in the Catalog of Federal Domestic Assistance; (2) Meet the funding... Federal assistance programs subject to subpart A if a State or Federal Program Agency fails to comply with... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false What Federal assistance programs are...
Code of Federal Regulations, 2010 CFR
2010-01-01
... Programs Receiving Federal Financial Assistance of the Office of Personnel Management C Appendix C to... Programs Receiving Federal Financial Assistance of the Office of Personnel Management Nondiscrimination in... subpart in programs receiving financial assistance under programs of the Office of Personnel Management...
ERIC Educational Resources Information Center
Quick, R. C.; And Others
1987-01-01
Outlines Cornell University's Employee Assistance Education and Research Program, which uses an academic curriculum and field experience to further develop the Employee Assistance Program (EAP) profession. Addresses the dilemma of personnel executives in ensuring quality in EAP programs and staff. (JOW)
Iraq: Recent Developments in Reconstruction Assistance
2005-05-12
in Reconstruction Assistance Summary Large-scale reconstruction assistance programs are being undertaken by the United States following the war with... assistance programs , the Coalition Provisional Authority (CPA), dissolved, and sovereignty was returned to Iraq. Security Council Resolution 1546 of June...Assessment.pdf]. Iraq: Recent Developments in Reconstruction Assistance Large-scale reconstruction assistance programs are being undertaken by the United
75 FR 18518 - Delaware; Major Disaster and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-12
..., including snow assistance, under the Public Assistance program for any continuous 48-hour period during or... protective measures (Category B), including snow assistance, under the Public Assistance program for any... Delaware are eligible to apply for assistance under the Hazard Mitigation Grant Program. The following...
46 CFR 16.401 - Employee Assistance Program (EAP).
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 1 2010-10-01 2010-10-01 false Employee Assistance Program (EAP). 16.401 Section 16.401 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MERCHANT MARINE OFFICERS AND SEAMEN CHEMICAL TESTING Employee Assistance Programs § 16.401 Employee Assistance Program (EAP). The employer shall provide an...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-18
... Information Collection: Comment Request; Assisted Living Conversion Program (ALCP) for Eligible Multifamily.... This Notice also lists the following information: Title of Proposal: Assisted Living Conversion Program.... Description of the need for the information and proposed use: The Assisted Living Conversion Program and the...
75 FR 11903 - District of Columbia; Major Disaster and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-12
..., including snow assistance, under the Public Assistance program for any continuous 48-hour period during or...), including snow assistance, under the Public Assistance program for any continuous 48-hour period during or... Hazard Mitigation Grant Program. (The following Catalog of Federal Domestic Assistance Numbers (CFDA) are...
Iraq: Reconstruction Assistance
2007-06-25
Iraq: Reconstruction Assistance Summary A large-scale assistance program has been undertaken by the United States in Iraq since mid-2003. To date...28, 2004, the entity implementing assistance programs , the Coalition Provisional Authority (CPA), dissolved, and sovereignty was returned to Iraq. U.N...10 U.S. Assistance Policy and Program Structure . . . . . . . . . . . . . . . . . . . . . . . . . . 11 U.S. Reconstruction
ERIC Educational Resources Information Center
Interagency Low Income Opportunity Advisory Board, Washington, DC.
This volume contains the second half of part 1 of a 4-part compendium of information about low income assistance programs plus the remaining 3 parts of the compendium. Part 1 contains detailed information about 59 major federally supported public assistance programs, each of which annually spent over $20 million in fiscal year 1985, and applied a…
75 FR 26977 - Massachusetts; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-13
... assistance, under the Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees. Consistent with the requirement that Federal assistance is supplemental, any Federal... assistance, under the Public Assistance program. The following Catalog of Federal Domestic Assistance Numbers...
75 FR 6404 - Oklahoma; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2010-02-09
... to direct Federal assistance, under the Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees. Consistent with the requirement that Federal assistance... assistance, under the Public Assistance program. The following Catalog of Federal Domestic Assistance Numbers...
10 CFR Appendix A to Subpart E of... - DOE Federally Assisted Programs Containing Age Distinctions
Code of Federal Regulations, 2013 CFR
2013-01-01
... 10 Energy 4 2013-01-01 2013-01-01 false DOE Federally Assisted Programs Containing Age...) NONDISCRIMINATION IN FEDERALLY ASSISTED PROGRAMS OR ACTIVITIES Nondiscrimination on the Basis of Age-Age... Federally Assisted Programs Containing Age Distinctions Statute, Name, Public Law, and U.S. Code Section and...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-22
... Information Collection; Comment Request: Tax Credit Assistance Program (TCAP) AGENCY: Office of the Chief... information: Title of Proposed: Tax Credit Assistance Program (TCAP). OMB Approval Number: 2506-0181. Form Numbers: None. Description of the need for the information and proposed use: Tax Credit Assistance Program...
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 3 2010-01-01 2010-01-01 false Grant awards for State programs to provide technical assistance, program assistance, and marketing. 455.144 Section 455.144 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION GRANT PROGRAMS FOR SCHOOLS AND HOSPITALS AND BUILDINGS OWNED BY UNITS OF LOCAL GOVERNMENT AND PUBLIC CARE INSTITUTIONS Grant Awards §...
76 FR 23272 - FY 2011 Emergency Food Assistance Annual Program Statement
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-26
... Emergency Food Assistance Annual Program Statement Pursuant to the Food for Peace Act of 2008 and the Foreign Assistance Act of 1961 (FAA), notice is hereby given that the FY 2011 Emergency Food Assistance... to review, the FY 2011 Emergency Food Assistance Annual Program Statement is available via the Food...
44 CFR 204.25 - FEMA-State agreement for fire management assistance grant program.
Code of Federal Regulations, 2010 CFR
2010-10-01
... GRANT PROGRAM Declaration Process § 204.25 FEMA-State agreement for fire management assistance grant... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false FEMA-State agreement for fire management assistance grant program. 204.25 Section 204.25 Emergency Management and Assistance FEDERAL...
44 CFR 204.25 - FEMA-State agreement for fire management assistance grant program.
Code of Federal Regulations, 2014 CFR
2014-10-01
... GRANT PROGRAM Declaration Process § 204.25 FEMA-State agreement for fire management assistance grant... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false FEMA-State agreement for fire management assistance grant program. 204.25 Section 204.25 Emergency Management and Assistance FEDERAL...
44 CFR 204.25 - FEMA-State agreement for fire management assistance grant program.
Code of Federal Regulations, 2011 CFR
2011-10-01
... GRANT PROGRAM Declaration Process § 204.25 FEMA-State agreement for fire management assistance grant... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false FEMA-State agreement for fire management assistance grant program. 204.25 Section 204.25 Emergency Management and Assistance FEDERAL...
44 CFR 204.25 - FEMA-State agreement for fire management assistance grant program.
Code of Federal Regulations, 2012 CFR
2012-10-01
... GRANT PROGRAM Declaration Process § 204.25 FEMA-State agreement for fire management assistance grant... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true FEMA-State agreement for fire management assistance grant program. 204.25 Section 204.25 Emergency Management and Assistance FEDERAL...
44 CFR 204.25 - FEMA-State agreement for fire management assistance grant program.
Code of Federal Regulations, 2013 CFR
2013-10-01
... GRANT PROGRAM Declaration Process § 204.25 FEMA-State agreement for fire management assistance grant... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false FEMA-State agreement for fire management assistance grant program. 204.25 Section 204.25 Emergency Management and Assistance FEDERAL...
25 CFR 20.505 - What services are provided jointly with the Child Assistance Program?
Code of Federal Regulations, 2010 CFR
2010-04-01
... 25 Indians 1 2010-04-01 2010-04-01 false What services are provided jointly with the Child... SERVICES FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Child Assistance How Child Assistance Funds Can Be Used § 20.505 What services are provided jointly with the Child Assistance Program? The services...
1998-08-04
This notice with comment period interprets the term "Federal public benefit" as used in Title IV of the Personal Responsibility and Work Opportunity Reconciliation Act of 1996 (PRWORA), Pub. L. 104-193, and identifies the HHS programs that provide such benefits under this interpretation. According to section 401 if PRWORA, aliens who are not "qualified aliens" are not eligible for any "Federal public benefit," unless the "Federal public benefit" falls within a specified exception. A "Federal public benefit" includes "any grant, contract, loan, professional license, or commercial license" provided to an individual, and also "any retirement, welfare, health, disability, public or assisted housing, postsecondary education, food assistance, unemployment benefit, or any other similar benefit for which payments or assistance are provided to an individual, household, or family eligibility unit." Under section 432, providers of a non-exempt "Federal public benefit" must verify that a person applying for the benefit is a qualified alien and is eligible to receive the benefit. The HHS programs that provide "Federal public benefits" and are not otherwise excluded from the definition by the exceptions provided in section 401(b) are: Adoption Assistance Administration on Developmental Disabilities (ADD)-State Developmental Disabilities Councils (direct services only) ADD-Special Projects (direct services only) ADD-University Affiliated Programs (clinical disability assessment services only) Adult Programs/Payments to Territories Agency for Health Care Policy and Research Dissertation Grants Child Care and Development Fund Clinical Training Grant for Faculty Development in Alcohol & Drug Abuse Foster Care Health Profession Education and Training Assistance Independent Living Program Job Opportunities for Low Income Individuals (JOLI) Low Income Home Energy Assistance Program (LIHEAP) Medicare Medicaid (except assistance for an emergency medical condition) Mental Health Clinical Training Grants Native Hawaiian Loan Program Refugee Cash Assistance Refugee Medical Assistance Refugee Preventive Health Services Program Refugee Social Services Formula Program Refugee Social Services Discretionary Program Refugee Targeted Assistance Formula Program Refugee Targeted Assistance Discretionary Program Refugee Unaccompanied Minors Program Refugee Voluntary Agency Matching Grant Program Repatriation Program Residential Energy Assistance Challenge Option (REACH) Social Services Block Grant (SSBG) State Child Health Insurance Program (CHIP) Temporary Assistance for Needy Families (TANF) While all of these programs provide "Federal public benefits" this does not mean that all benefits or services provided under these programs are "Federal public benefits." As discussed in sections II and III below, some benefits or services under these programs may not be provided to an "individual, household, or family eligibility unit" and, therefore, do not constitute "Federal public benefits" as defined by PRWORA.
Information about Federal Assistance Listings and the Catalog of Federal Domestic Assistance
The primary purpose of the Catalog is to assist potential applicants in identifying programs which meet their specific objectives & to provide general information on Federal assistance programs. In 1977 Congress passed the Federal Program Information Act.
26 CFR 1.127-1 - Amounts received under a qualified educational assistance program.
Code of Federal Regulations, 2010 CFR
2010-04-01
... employee under a qualified educational assistance program described in § 1.127-2, or (2) The value of... assistance program. 1.127-1 Section 1.127-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE... Income § 1.127-1 Amounts received under a qualified educational assistance program. (a) Exclusion from...
Analysis of Organizational Architectures for the Air Force Tuition Assistance Program
2003-03-01
FORCE TUITION ASSISTANCE PROGRAM THESIS Krista Zimmerman LaPietra AFIT/GOR/ENS/03-15 DEPARTMENT OF THE AIR FORCE AIR UNIVERSITY AIR...ANALYSIS OF ORGANIZATIONAL ARCHITECTURES FOR THE AIR FORCE TUITION ASSISTANCE PROGRAM THESIS Presented to the Faculty Department...ANALYSIS OF ORGANIZATIONAL ARCHITECTURES FOR THE AIR FORCE TUITION ASSISTANCE PROGRAM Krista Zimmerman LaPietra, BS
Code of Federal Regulations, 2012 CFR
2012-07-01
... assistance programs and projects funded by the Federal Highway Trust Fund? 205.16 Section 205.16 Money and... special rules apply to Federal assistance programs and projects funded by the Federal Highway Trust Fund? The following applies to Federal assistance programs and projects funded out of the Federal Highway...
Code of Federal Regulations, 2013 CFR
2013-07-01
... assistance programs and projects funded by the Federal Highway Trust Fund? 205.16 Section 205.16 Money and... special rules apply to Federal assistance programs and projects funded by the Federal Highway Trust Fund? The following applies to Federal assistance programs and projects funded out of the Federal Highway...
Code of Federal Regulations, 2014 CFR
2014-07-01
... assistance programs and projects funded by the Federal Highway Trust Fund? 205.16 Section 205.16 Money and... special rules apply to Federal assistance programs and projects funded by the Federal Highway Trust Fund? The following applies to Federal assistance programs and projects funded out of the Federal Highway...
Code of Federal Regulations, 2010 CFR
2010-07-01
... assistance programs and projects funded by the Federal Highway Trust Fund? 205.16 Section 205.16 Money and... special rules apply to Federal assistance programs and projects funded by the Federal Highway Trust Fund? The following applies to Federal assistance programs and projects funded out of the Federal Highway...
Code of Federal Regulations, 2011 CFR
2011-07-01
... assistance programs and projects funded by the Federal Highway Trust Fund? 205.16 Section 205.16 Money and... special rules apply to Federal assistance programs and projects funded by the Federal Highway Trust Fund? The following applies to Federal assistance programs and projects funded out of the Federal Highway...
The Technical Assistance Program: A Program Plan.
1985-09-01
interests, talents, and hobbies of current employees who wish to become involved in the technical assistance program . 4. Capitalize on the corporate...Center San Diego, CA 92152 Telephone (619) 225-6281 B-33 TAP ( EMPLOYEE ) QUESTIONNAIRE - The Technical Assistance Program (TAP) links technically skilled...Brochure, "Retired Technologist" C-11 C. Sample Letter to NOSC Employees C-13 Brochure D. The Technical Assistance Program C-15 C-1
76 FR 61374 - Massachusetts; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-04
...), including direct Federal assistance, under the Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees. Consistent with the requirement that Federal assistance... protective measures (Category B), including direct Federal assistance, under the Public Assistance program...
76 FR 60849 - Vermont; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-30
... to direct Federal assistance, under the Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees. Consistent with the requirement that Federal assistance... the Public Assistance program. (The following Catalog of Federal Domestic Assistance Numbers (CFDA...
40 CFR 52.183 - Small business assistance program.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Small business assistance program. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arkansas § 52.183 Small business assistance... a Small Business Stationary Source Technical and Environmental Compliance Assistance Program...
40 CFR 52.183 - Small business assistance program.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 3 2013-07-01 2013-07-01 false Small business assistance program. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arkansas § 52.183 Small business assistance... a Small Business Stationary Source Technical and Environmental Compliance Assistance Program...
40 CFR 52.183 - Small business assistance program.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 3 2012-07-01 2012-07-01 false Small business assistance program. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arkansas § 52.183 Small business assistance... a Small Business Stationary Source Technical and Environmental Compliance Assistance Program...
40 CFR 52.183 - Small business assistance program.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 3 2014-07-01 2014-07-01 false Small business assistance program. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arkansas § 52.183 Small business assistance... a Small Business Stationary Source Technical and Environmental Compliance Assistance Program...
40 CFR 52.183 - Small business assistance program.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 3 2011-07-01 2011-07-01 false Small business assistance program. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arkansas § 52.183 Small business assistance... a Small Business Stationary Source Technical and Environmental Compliance Assistance Program...
76 FR 72961 - Massachusetts; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-28
... (Category B), limited to direct Federal assistance, under the Public Assistance program. This assistance... assistance, under the Public Assistance program. The following Catalog of Federal Domestic Assistance Numbers... T. Stafford Disaster Relief and Emergency Assistance Act, 42 U.S.C. 5121-5207 (the Stafford Act), as...
Food Assistance Programs and Child Health
ERIC Educational Resources Information Center
Gundersen, Craig
2015-01-01
Food assistance programs--including the Supplemental Nutrition Assistance Program (SNAP, or food stamps), the National School Lunch Program, and the School Breakfast Program--have been remarkably successful at their core mission: reducing food insecurity among low-income children. Moreover, writes Craig Gundersen, SNAP in particular has also been…
Status Report on the Virginia Beginning Teacher Assistance Program.
ERIC Educational Resources Information Center
Caldwell, Michael
This report presents a description of the Virgina Beginning Teacher Assistance Program (BTAP), its background and rationale, development, major program assumptions, and major program activities. The Virginia BTAP has three major components: teacher assessment, teacher assistance, and program management. The development and implementation of each…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-08
... Care Act Medicare Beneficiary Outreach and Assistance Program Funding for Title VI Native American Programs Purpose of Notice: Availability of funding opportunity announcement. Funding Opportunity Title/Program Name: Affordable Care Act Medicare Beneficiary Outreach and Assistance Program Funding for Title...
76 FR 60850 - Rhode Island; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-30
...), including direct Federal assistance, under the Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees. Consistent with the requirement that Federal assistance...), including direct federal assistance, under the Public Assistance program. The following Catalog of Federal...
76 FR 61372 - New Hampshire; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-04
...), including direct Federal assistance, under the Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees. Consistent with the requirement that Federal assistance... the Public Assistance program. (The following Catalog of Federal Domestic Assistance Numbers (CFDA...
76 FR 32368 - Mississippi; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-06
... assistance, under the Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees. Consistent with the requirement that Federal assistance is supplemental, any Federal... protective measures (Category B), limited to direct Federal assistance, under the Public Assistance program...
Information about the Catalog of Federal Domestic Assistance and EPA Programs
The primary purpose of the Catalog is to assist potential applicants in identifying programs which meet their specific objectives & to provide general information on Federal assistance programs. In 1977 Congress passed the Federal Program Information Act.
40 CFR 52.991 - Small business assistance program.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Small business assistance program. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Louisiana § 52.991 Small business assistance... a Small Business Stationary Source Technical and Environmental Compliance Assistance Program to meet...
40 CFR 52.991 - Small business assistance program.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 3 2012-07-01 2012-07-01 false Small business assistance program. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Louisiana § 52.991 Small business assistance... a Small Business Stationary Source Technical and Environmental Compliance Assistance Program to meet...
40 CFR 52.991 - Small business assistance program.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 3 2013-07-01 2013-07-01 false Small business assistance program. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Louisiana § 52.991 Small business assistance... a Small Business Stationary Source Technical and Environmental Compliance Assistance Program to meet...
40 CFR 52.991 - Small business assistance program.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 3 2014-07-01 2014-07-01 false Small business assistance program. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Louisiana § 52.991 Small business assistance... a Small Business Stationary Source Technical and Environmental Compliance Assistance Program to meet...
40 CFR 52.991 - Small business assistance program.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 3 2011-07-01 2011-07-01 false Small business assistance program. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Louisiana § 52.991 Small business assistance... a Small Business Stationary Source Technical and Environmental Compliance Assistance Program to meet...
76 FR 12073 - Extension of Web-Based TRICARE Assistance Program Demonstration Program
Federal Register 2010, 2011, 2012, 2013, 2014
2011-03-04
... DEPARTMENT OF DEFENSE Office of the Secretary Extension of Web-Based TRICARE Assistance Program Demonstration Program AGENCY: Department of Defense. ACTION: Notice of a Two Year Extension of the Web-Based..., entitled Web-Based TRICARE Assistance Program. This demonstration was effective August 1, 2009, as...
40 CFR 35.9030 - Work program.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Work program. 35.9030 Section 35.9030 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Financial Assistance for the National Estuary Program § 35.9030 Work program. The work program is...
40 CFR 35.9030 - Work program.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Work program. 35.9030 Section 35.9030 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Financial Assistance for the National Estuary Program § 35.9030 Work program. The work program is...
40 CFR 35.9030 - Work program.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Work program. 35.9030 Section 35.9030 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Financial Assistance for the National Estuary Program § 35.9030 Work program. The work program is...
40 CFR 35.9030 - Work program.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Work program. 35.9030 Section 35.9030 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Financial Assistance for the National Estuary Program § 35.9030 Work program. The work program is...
40 CFR 35.9030 - Work program.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Work program. 35.9030 Section 35.9030 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Financial Assistance for the National Estuary Program § 35.9030 Work program. The work program is...
10 CFR 26.35 - Employee assistance programs.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 10 Energy 1 2013-01-01 2013-01-01 false Employee assistance programs. 26.35 Section 26.35 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Program Elements § 26.35 Employee assistance programs. (a) Each licensee and other entity who is subject to this part shall maintain an EAP to...
10 CFR 26.35 - Employee assistance programs.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 10 Energy 1 2014-01-01 2014-01-01 false Employee assistance programs. 26.35 Section 26.35 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Program Elements § 26.35 Employee assistance programs. (a) Each licensee and other entity who is subject to this part shall maintain an EAP to...
10 CFR 26.35 - Employee assistance programs.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 10 Energy 1 2012-01-01 2012-01-01 false Employee assistance programs. 26.35 Section 26.35 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Program Elements § 26.35 Employee assistance programs. (a) Each licensee and other entity who is subject to this part shall maintain an EAP to...
10 CFR 26.35 - Employee assistance programs.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 1 2010-01-01 2010-01-01 false Employee assistance programs. 26.35 Section 26.35 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Program Elements § 26.35 Employee assistance programs. (a) Each licensee and other entity who is subject to this part shall maintain an EAP to...
10 CFR 26.35 - Employee assistance programs.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 1 2011-01-01 2011-01-01 false Employee assistance programs. 26.35 Section 26.35 Energy NUCLEAR REGULATORY COMMISSION FITNESS FOR DUTY PROGRAMS Program Elements § 26.35 Employee assistance programs. (a) Each licensee and other entity who is subject to this part shall maintain an EAP to...
76 FR 61373 - Connecticut; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-04
... assistance, under the Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees. Consistent with the requirement that Federal assistance is supplemental, any Federal... Assistance program. The following Catalog of Federal Domestic Assistance Numbers (CFDA) are to be used for...
76 FR 60852 - District of Columbia; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-30
...), including direct Federal assistance, under the Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees. Consistent with the requirement that Federal assistance... measures (Category B), including direct federal assistance, under the Public Assistance program for the...
76 FR 61726 - North Carolina; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-05
...), including direct Federal assistance, under the Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees. Consistent with the requirement that Federal assistance...), including direct federal assistance, under the Public Assistance program at 75 percent federal funding. The...
Iraq: Recent Developments in Reconstruction Assistance
2005-03-23
Developments in Reconstruction Assistance Summary Large-scale reconstruction assistance programs are being undertaken by the United States following the war...currently the case. The House approved the measure on March 16. On June 28, 2004, the entity implementing assistance programs , the Coalition Provisional...Large-scale reconstruction assistance programs are being undertaken by the United States in Iraq. This report describes recent developments in this
48 CFR 519.7012 - Developmental assistance.
Code of Federal Regulations, 2010 CFR
2010-10-01
... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS GSA Mentor-Protégé Program 519.7012 Developmental assistance. The forms of developmental assistance a mentor can provide to a protégé include: (a) Management... Mentor-Protégé Program Manager. ...
Incorporating Health Education into Employee Assistance Programs.
ERIC Educational Resources Information Center
Miller, Richard E.
1985-01-01
Methods of aligning health education with the goals and functions of employee assistance programs are discussed. The role of the health educator in developing these programs is explained in a description of employee assistance program service standards and specific sub-tasks. (DF)
Code of Federal Regulations, 2010 CFR
2010-01-01
... costs for such program; (4) The energy conservation measures funded from non-Federal sources under this... non-Federal sources of funding to carry out the State's program(s) for energy conservation measures... 10 Energy 3 2010-01-01 2010-01-01 false Grant applications for State technical assistance, program...
75 FR 15693 - Extension of Web-Based TRICARE Assistance Program Demonstration Project
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-30
... DEPARTMENT OF DEFENSE Office of the Secretary Extension of Web-Based TRICARE Assistance Program Demonstration Project AGENCY: Department of Defense (DoD). ACTION: Notice of a Web-Based TRICARE Assistance... States Code, Section 1092, entitled Web-Based TRICARE Assistance Program. This demonstration was...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-24
... DEPARTMENT OF THE TREASURY Internal Revenue Service Community Volunteer Income Tax Assistance... application packages for the 2012 Community Volunteer Income Tax Assistance (VITA) Matching Grant Program... Community Volunteer Income Tax Assistance (VITA) Matching Grant Program is contained in the Department of...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-05
... DEPARTMENT OF THE TREASURY Internal Revenue Service Community Volunteer Income Tax Assistance... application package for the 2013 Community Volunteer Income Tax Assistance (VITA) Matching Grant Program... the Community Volunteer Income Tax Assistance (VITA) Matching Grant Program is contained in the...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-28
... DEPARTMENT OF THE TREASURY Internal Revenue Service Community Volunteer Income Tax Assistance... application packages for the 2011 Community Volunteer Income Tax Assistance (VITA) Matching Grant Program... for the 2011 Community Volunteer Income Tax Assistance (VITA) Matching Grant Demonstration Program for...
45 CFR 205.50 - Safeguarding information for the financial assistance programs.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 45 Public Welfare 2 2013-10-01 2012-10-01 true Safeguarding information for the financial assistance programs. 205.50 Section 205.50 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH...
45 CFR 205.50 - Safeguarding information for the financial assistance programs.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 45 Public Welfare 2 2012-10-01 2012-10-01 false Safeguarding information for the financial assistance programs. 205.50 Section 205.50 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH...
45 CFR 205.50 - Safeguarding information for the financial assistance programs.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 45 Public Welfare 2 2014-10-01 2012-10-01 true Safeguarding information for the financial assistance programs. 205.50 Section 205.50 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH...
7 CFR 4279.279 - Domestic lamb industry adjustment assistance program.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 7 Agriculture 15 2013-01-01 2013-01-01 false Domestic lamb industry adjustment assistance program. 4279.279 Section 4279.279 Agriculture Regulations of the Department of Agriculture (Continued) RURAL... Biorefinery Assistance Loans § 4279.279 Domestic lamb industry adjustment assistance program. The provisions...
7 CFR 4279.279 - Domestic lamb industry adjustment assistance program.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 7 Agriculture 15 2012-01-01 2012-01-01 false Domestic lamb industry adjustment assistance program. 4279.279 Section 4279.279 Agriculture Regulations of the Department of Agriculture (Continued) RURAL... Biorefinery Assistance Loans § 4279.279 Domestic lamb industry adjustment assistance program. The provisions...
7 CFR 4279.279 - Domestic lamb industry adjustment assistance program.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 7 Agriculture 15 2014-01-01 2014-01-01 false Domestic lamb industry adjustment assistance program. 4279.279 Section 4279.279 Agriculture Regulations of the Department of Agriculture (Continued) RURAL... Biorefinery Assistance Loans § 4279.279 Domestic lamb industry adjustment assistance program. The provisions...
DOT National Transportation Integrated Search
2001-01-01
This manual is a companion piece to the Commuter Assistance Program Evaluation Manual that was developed to assist Florida's Commuter Assistance Programs (CAP) in their efforts to measure and evaluate their performance. This manual is intended to pro...
New developments in employee assistance programs.
White, R K; McDuff, D R; Schwartz, R P; Tiegel, S A; Judge, C P
1996-04-01
Employee assistance programs have developed from alcoholism assessment and referral centers to specialized behavioral health programs. Comprehensive employee assistance programs are defined by six major components: identification of problems based on job performance, consultation with supervisors, constructive confrontation, evaluation and referral, liaison with treatment providers, and substance abuse expertise. Other services have been added as enhancements to the basic model and include managed behavioral health activities and professional assistance committees, which provide services for impaired professionals and executives. Recent developments in the field are illustrated through examples from the experience of the employee assistance program at the University of Maryland Medical System in Baltimore.
75 FR 25873 - West Virginia; Major Disaster and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-10
... provide emergency protective measures, including snow assistance, under the Public Assistance program for... assistance, as warranted. This assistance excludes regular time costs for the sub-grantees' regular employees..., (Category B), including snow assistance, under the Public Assistance program for any continuous 48-hour...
2000-04-01
AD Award Number: DAMD17-98-2-8012 TITLE: Technical Assistance and Program Support; DOD Historical Black Colleges and Universities and Minority...2000 3. REPORT TYPE AND DATES COVERED Annual (1 May 99 - 30 Apr 00): 4. TITLE AND SUBTITLE Technical Assistance and Program Support; DOD...UNCF’s Infrastructure Development Assistance Program (IDAP) has been involved myriad of tasks to support the Department of Defense’s interest to
Legal Services: The Army Legal Assistance Program
1996-02-21
Army Regulation 27–3 Legal Services The Army Legal Assistance Program Headquarters Department of the Army Washington, DC 21 February 1996 REPORT...1996 to xx-xx-1996 4. TITLE AND SUBTITLE The Army Legal Assistance Program Unclassified 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT...Z39.18 SUMMARY of CHANGE AR 27–3 The Army Legal Assistance Program This change 2 corrects the title page of this regulation. This change 2-- o Corrects
Federal Assistance for Programs Serving the Handicapped. Third Edition.
ERIC Educational Resources Information Center
Office of Human Development (DHEW), Washington, DC. Office for Handicapped Individuals.
The guide presents information on more than 200 federally assisted programs serving the handicapped. Information on uses and restrictions, types of assistance, eligibility requirements; application procedures, appropriations, program accomplishments, enabling legislation, and contact persons are listed for programs receiving four types of…
Real Estate: Homeowners Assistance Program
1992-06-12
Army Regulation 405–16 Real Estate Homeowners Assistance Program Headquarters Department of the Army Washington, DC 12 June 1992 UNCLASSIFIED Report...Classification of Abstract unclassified Limitation of Abstract UU Number of Pages 23 SUMMARY of CHANGE AR 405–16 Homeowners Assistance Program This...properties acquired under the Homeowners Assistance Program (HAP) (para 7). o Delegates to Chief of Engineers, with the power to redelegate, execution of deeds
Code of Federal Regulations, 2014 CFR
2014-04-01
... for homeownership assistance for disabled families. 982.642 Section 982.642 Housing and Urban... option: Pilot program for homeownership assistance for disabled families. (a) General. This section... Act of 2000. Under the pilot program, a PHA may provide homeownership assistance to a disabled family...
Code of Federal Regulations, 2011 CFR
2011-04-01
... for homeownership assistance for disabled families. 982.642 Section 982.642 Housing and Urban... option: Pilot program for homeownership assistance for disabled families. (a) General. This section... Act of 2000. Under the pilot program, a PHA may provide homeownership assistance to a disabled family...
Code of Federal Regulations, 2010 CFR
2010-04-01
... for homeownership assistance for disabled families. 982.642 Section 982.642 Housing and Urban... option: Pilot program for homeownership assistance for disabled families. (a) General. This section... Act of 2000. Under the pilot program, a PHA may provide homeownership assistance to a disabled family...
Code of Federal Regulations, 2012 CFR
2012-04-01
... for homeownership assistance for disabled families. 982.642 Section 982.642 Housing and Urban... option: Pilot program for homeownership assistance for disabled families. (a) General. This section... Act of 2000. Under the pilot program, a PHA may provide homeownership assistance to a disabled family...
Code of Federal Regulations, 2013 CFR
2013-04-01
... for homeownership assistance for disabled families. 982.642 Section 982.642 Housing and Urban... option: Pilot program for homeownership assistance for disabled families. (a) General. This section... Act of 2000. Under the pilot program, a PHA may provide homeownership assistance to a disabled family...
45 CFR 2540.100 - What restrictions govern the use of Corporation assistance?
Code of Federal Regulations, 2010 CFR
2010-10-01
... part of the assigned duties of such employee. (5) A participant in any program receiving assistance... of a participant in a program receiving Corporation assistance. (2) An organization may not displace a volunteer by using a participant in a program receiving Corporation assistance. (3) A service...
Comparison of In-House and Contracted-Out Employee Assistance Programs.
ERIC Educational Resources Information Center
Straussner, Shulamith Lala Ashenberg
1988-01-01
Compared 15 selected management-sponsored in-house and eight contracted-out employee assistance programs in the New York area. Examined advantages and disadvantages of in-house and contractual programs from the viewpoints of top management, employees, and the employee assistance program itself. Concluded that which program model was best depended…
Iraq: Recent Developments in Reconstruction Assistance
2005-01-27
Developments in Reconstruction Assistance Summary Large-scale reconstruction assistance programs are being undertaken by the United States following the war...in grant aid and as much as $13.3 billion in possible loans. On June 28, 2004, the entity implementing assistance programs , the Coalition Provisional... programs are being undertaken by the United States in Iraq. This report describes recent developments in this assistance effort. The report will be updated
Iraq: Recent Developments in Reconstruction Assistance
2004-12-20
Developments in Reconstruction Assistance Summary Large-scale reconstruction assistance programs are being undertaken by the United States following the war...in grant aid and as much as $13.3 billion in possible loans. On June 28, 2004, the entity implementing assistance programs , the Coalition... programs are being undertaken by the United States in Iraq. This report describes recent developments in this assistance effort. The report will be
Federal Register 2010, 2011, 2012, 2013, 2014
2010-11-10
... Expenditures; Federal Matching Shares for Medicaid, the Children's Health Insurance Program, and Aid to Needy... assistance (Medicaid) and Children's Health Insurance Program (CHIP) expenditures, Temporary Assistance for... expenditures for most medical assistance and child health assistance, and assistance payments for certain...
7 CFR 762.150 - Interest assistance program.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 7 Agriculture 7 2014-01-01 2014-01-01 false Interest assistance program. 762.150 Section 762.150 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS GUARANTEED FARM LOANS § 762.150 Interest assistance program. (a) Requests for...
36 CFR 230.21 - Implementation of the program.
Code of Federal Regulations, 2010 CFR
2010-07-01
.... 230.21 Section 230.21 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE STATE AND PRIVATE FORESTRY ASSISTANCE Urban and Community Forestry Assistance Program § 230.21 Implementation of the program. (a) The Urban and Community Forestry Assistance Program is implemented through the...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-25
... ``Homeless Veterans' Reintegration Program (HVRP) National Technical Assistance Center Cooperative Agreement...). Section 2021 authorizes programs to expedite the reintegration of homeless Veterans into the labor force... Technical Assistance Center (NTAC) for the Homeless Veterans' Reintegration Program (HVRP) to include the...
28 CFR 92.10 - Providing tutorials and other academic assistance programs.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Providing tutorials and other academic... tutorials and other academic assistance programs. (a) The program designed by the community organization must include academic counseling, tutorials and other academic assistance programs to enable...
28 CFR 92.10 - Providing tutorials and other academic assistance programs.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Providing tutorials and other academic... tutorials and other academic assistance programs. (a) The program designed by the community organization must include academic counseling, tutorials and other academic assistance programs to enable...
28 CFR 92.10 - Providing tutorials and other academic assistance programs.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Providing tutorials and other academic... tutorials and other academic assistance programs. (a) The program designed by the community organization must include academic counseling, tutorials and other academic assistance programs to enable...
28 CFR 92.10 - Providing tutorials and other academic assistance programs.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Providing tutorials and other academic... tutorials and other academic assistance programs. (a) The program designed by the community organization must include academic counseling, tutorials and other academic assistance programs to enable...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-06
..., Energy Branch, Attention: BioRefinery Assistance Program, 1400 Independence Avenue, SW., STOP 3225... to USDA's Rural Development National Office: Energy Branch, Attention: BioRefinery Assistance Program...
Veterans Employment Assistance Program
1985-03-28
Department of-Defense ’)IRECTIVE AD-A270 588 March 28, 1985 NUMBER 1341.6 ASD(MI sUBJECT: Veterans Employment Assistance Program Reference: (a) DoD...Instruction 1404.9, "Vietnam Era Veterans Employment Assistance Program ," August 28, 1974 (hereby canceled) (b) Title 38, United States Code, Section...assessment of local needs. b. As considered necessary, each DoD Component shall assess the status of the Veterans Employment Assistance Program and determine
76 FR 32369 - Tennessee; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-06
..., under the Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees. Consistent with the requirement that Federal assistance is supplemental, any Federal... Public Assistance program. The following Catalog of Federal Domestic Assistance Numbers (CFDA) are to be...
76 FR 34089 - Louisiana; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-10
... the Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees. Consistent with the requirement that Federal assistance is supplemental, any Federal funds... direct Federal assistance, under the Public Assistance program. The following Catalog of Federal Domestic...
76 FR 60851 - Maryland; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-30
...), including direct Federal assistance, under the Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees. Consistent with the requirement that Federal assistance... program at 75 percent Federal funding. The following Catalog of Federal Domestic Assistance Numbers (CFDA...
77 FR 41193 - Ohio; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-12
... protective measures (Category B), limited to direct Federal assistance, under the Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees. Consistent with the... (Category B), limited to direct federal assistance, under the Public Assistance program. The following...
75 FR 16819 - Minnesota; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-02
... protective measures (Category B), limited to direct Federal assistance, under the Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees. Consistent with the...), limited to direct Federal assistance, under the Public Assistance program. The following Catalog of...
Evaluation of the Refugee Targeted Assistance Grants Program: Phase I, Final Report.
ERIC Educational Resources Information Center
Cichon, Donald; And Others
This report presents findings of the first phase of an evaluation of the Targeted Assistance Program (TAP), A Federal program which funds services and projects that assist refugees in attaining economic self-sufficiency and reduced dependency upon public assistance. Following an executive summary and other materials, the report is divided into…
15 CFR 8.6 - Applicability of this part to Department assisted programs.
Code of Federal Regulations, 2010 CFR
2010-01-01
... NONDISCRIMINATION IN FEDERALLY ASSISTED PROGRAMS OF THE DEPARTMENT OF COMMERCE-EFFECTUATION OF TITLE VI OF THE CIVIL... § 8.6 Applicability of this part to Department assisted programs. The following examples illustrate.... A current example of such assistance is that received by State maritime academies or colleges, by...
15 CFR 8.6 - Applicability of this part to Department assisted programs.
Code of Federal Regulations, 2014 CFR
2014-01-01
... NONDISCRIMINATION IN FEDERALLY ASSISTED PROGRAMS OF THE DEPARTMENT OF COMMERCE-EFFECTUATION OF TITLE VI OF THE CIVIL... § 8.6 Applicability of this part to Department assisted programs. The following examples illustrate.... A current example of such assistance is that received by State maritime academies or colleges, by...
15 CFR 8.6 - Applicability of this part to Department assisted programs.
Code of Federal Regulations, 2011 CFR
2011-01-01
... NONDISCRIMINATION IN FEDERALLY ASSISTED PROGRAMS OF THE DEPARTMENT OF COMMERCE-EFFECTUATION OF TITLE VI OF THE CIVIL... § 8.6 Applicability of this part to Department assisted programs. The following examples illustrate.... A current example of such assistance is that received by State maritime academies or colleges, by...
15 CFR 8.6 - Applicability of this part to Department assisted programs.
Code of Federal Regulations, 2012 CFR
2012-01-01
... NONDISCRIMINATION IN FEDERALLY ASSISTED PROGRAMS OF THE DEPARTMENT OF COMMERCE-EFFECTUATION OF TITLE VI OF THE CIVIL... § 8.6 Applicability of this part to Department assisted programs. The following examples illustrate.... A current example of such assistance is that received by State maritime academies or colleges, by...
15 CFR 8.6 - Applicability of this part to Department assisted programs.
Code of Federal Regulations, 2013 CFR
2013-01-01
... NONDISCRIMINATION IN FEDERALLY ASSISTED PROGRAMS OF THE DEPARTMENT OF COMMERCE-EFFECTUATION OF TITLE VI OF THE CIVIL... § 8.6 Applicability of this part to Department assisted programs. The following examples illustrate.... A current example of such assistance is that received by State maritime academies or colleges, by...
2009-07-01
this survey include Erin St. Pierre and Scott Wiedmann (Federal Voting Assistance Program ). Other important contributors to the survey development...20 a. Federal Voting Assistance Program (FVAP) onsite VAO training workshop...the voting program .............................37 November 2008 Post-Election Voting Survey of Department of State Voting Assistance Officers
Code of Federal Regulations, 2010 CFR
2010-10-01
... statement of work is approved. (Approved by the Office of Management and Budget under OMB control number... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Criteria for program... Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS...
13 CFR 124.520 - Mentor/protege program.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Mentor/protege program. 124.520... § 124.520 Mentor/protege program. (a) General. The mentor/protege program is designed to encourage approved mentors to provide various forms of assistance to eligible Participants. This assistance may...
75 FR 45694 - Agency Information Collection Activity Under OMB Review
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-03
... approved information collection: 49 U.S.C. Sections 5310 and 5311--Capital Assistance Program for Elderly... Assistance Program for Elderly Persons and Persons with Disabilities and Nonurbanized Area Formula Program (OMB Number 2132-0500) Abstract: The Capital Assistance Program for Elderly Persons and Persons with...
Code of Federal Regulations, 2010 CFR
2010-04-01
..., DEPARTMENT OF THE INTERIOR HUMAN SERVICES FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Welfare Reform... agency programs? We will coordinate all financial assistance and social services programs with state... social services program avoids duplication of assistance. ...
Code of Federal Regulations, 2011 CFR
2011-04-01
..., DEPARTMENT OF THE INTERIOR HUMAN SERVICES FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Welfare Reform... agency programs? We will coordinate all financial assistance and social services programs with state... social services program avoids duplication of assistance. ...
Code of Federal Regulations, 2013 CFR
2013-04-01
..., DEPARTMENT OF THE INTERIOR HUMAN SERVICES FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Welfare Reform... agency programs? We will coordinate all financial assistance and social services programs with state... social services program avoids duplication of assistance. ...
Code of Federal Regulations, 2012 CFR
2012-04-01
..., DEPARTMENT OF THE INTERIOR HUMAN SERVICES FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Welfare Reform... agency programs? We will coordinate all financial assistance and social services programs with state... social services program avoids duplication of assistance. ...
Code of Federal Regulations, 2014 CFR
2014-04-01
..., DEPARTMENT OF THE INTERIOR HUMAN SERVICES FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Welfare Reform... agency programs? We will coordinate all financial assistance and social services programs with state... social services program avoids duplication of assistance. ...
Sellers, Debra M; Markham, Melinda Stafford
2012-01-01
The Fashion an Easier Lifestyle with Assistive Technology (FELAT) curriculum was developed as a needs-based, community educational program provided through a state Cooperative Extension Service. The overall goal for participants was to raise awareness of assistive technology. Program evaluation included a postassessment and subsequent interview to determine short-term knowledge gain and longer term behavior change. The sample consisted of mainly older, married females. The FELAT program was effective at raising awareness and increasing knowledge of assistive technology, and for many participants, the program acted as a catalyst for planning to or taking action related to assistive technology.
1999 commuter assistance program evaluation manual
DOT National Transportation Integrated Search
2001-01-01
This manual was developed to assist Florida's Commuter Assistance Programs (CAP) to measure and evaluate their performance. It provides information necessary for a CAP to create and implement its own evaluation program. It discusses performance measu...
ERIC Educational Resources Information Center
Mississippi Research and Curriculum Unit for Vocational and Technical Education, State College.
This document, which is intended for use by community and junior colleges throughout Mississippi, contains curriculum frameworks for the course sequences in the dental assisting technology program. Presented in the introductory section are a description of the program and suggested course sequence. Section I lists baseline competencies. Section II…
40 CFR 35.9070 - National program assistance agreements.
Code of Federal Regulations, 2013 CFR
2013-07-01
... FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Financial Assistance for the National Estuary Program § 35... award of NEP funds for work that has broad applicability to estuaries of national significance. These...
40 CFR 35.9070 - National program assistance agreements.
Code of Federal Regulations, 2014 CFR
2014-07-01
... FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Financial Assistance for the National Estuary Program § 35... award of NEP funds for work that has broad applicability to estuaries of national significance. These...
40 CFR 35.9070 - National program assistance agreements.
Code of Federal Regulations, 2010 CFR
2010-07-01
... FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Financial Assistance for the National Estuary Program § 35... award of NEP funds for work that has broad applicability to estuaries of national significance. These...
40 CFR 35.9070 - National program assistance agreements.
Code of Federal Regulations, 2012 CFR
2012-07-01
... FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Financial Assistance for the National Estuary Program § 35... award of NEP funds for work that has broad applicability to estuaries of national significance. These...
40 CFR 35.9070 - National program assistance agreements.
Code of Federal Regulations, 2011 CFR
2011-07-01
... FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Financial Assistance for the National Estuary Program § 35... award of NEP funds for work that has broad applicability to estuaries of national significance. These...
76 FR 32982 - Alabama; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-07
..., under the Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees. Consistent with the requirement that Federal assistance is supplemental, any Federal... Assistance program. The following Catalog of Federal Domestic Assistance Numbers (CFDA) are to be used for...
76 FR 21773 - North Dakota; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-18
..., under the Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees. Consistent with the requirement that Federal assistance is supplemental, any Federal... Public Assistance program. The following Catalog of Federal Domestic Assistance Numbers (CFDA) are to be...
75 FR 39554 - Texas; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-09
... Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees...), limited to direct Federal assistance, under the Public Assistance program. The following Catalog of... emergency declaration under the authority of the Robert T. Stafford Disaster Relief and Emergency Assistance...
Designing an Elderly Assistance Program Based-on Home Care
NASA Astrophysics Data System (ADS)
Umusya'adah, L.; Juwaedah, A.; Jubaedah, Y.; Ratnasusanti, H.; Puspita, R. H.
2018-02-01
PKH (Program Keluarga Harapan) is a program of Indonesia’s Government through the ministry of social directorate to accelerate the poverty reduction and the achievement of Millennium Development Goals (MDGs) target as well as the policies development in social protection and social welfare domain or commonly referred to as Indonesian Conditional Cash Transfer (CCT) Program. This research is motivated that existing participants of the family expectation program (PKH) that already exist in Sumedang, Indoensia, especially in the South Sumedang on the social welfare components is only limited to the health checking, while for assisting the elderly based Home Care program there has been no structured and systematic, where as the elderly still need assistance, especially from the family and community environment. This study uses a method of Research and Development with Model Addie which include analysis, design, development, implementation and evaluation. Participants in this study using purposive sampling, where selected families of PKH who provide active assistance to the elderly with 82 participants. The program is designed consists of program components: objectives, goals, forms of assistance, organizing institutions and implementing the program, besides, program modules include assisting the elderly. Form of assistance the elderly cover physical, social, mental and spiritual. Recommended for families and companions PKH, the program can be implemented to meet the various needs of the elderly. For the elderly should introspect, especially in the health and follow the advice recommended by related parties
75 FR 28673 - Notice of Request for Extension of a Currently Approved Information Collection
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-21
... approved information collection: 49 U.S.C. Sections 5310 and 5311--Capital Assistance Program for Elderly... Assistance Program for Elderly Persons and Persons with Disabilities and Nonurbanized Area Formula Program (OMB Number: 2132-0561) Background: The Capital Assistance Program for Elderly Persons and Persons with...
25 CFR 170.921 - What emergency or disaster assistance programs are available?
Code of Federal Regulations, 2010 CFR
2010-04-01
... have been damaged due to natural disasters (floods, hurricanes, tornadoes, etc.). (b) The Federal... 25 Indians 1 2010-04-01 2010-04-01 false What emergency or disaster assistance programs are... emergency or disaster assistance programs are available? (a) FHWA operates two emergency relief programs: (1...
25 CFR 170.921 - What emergency or disaster assistance programs are available?
Code of Federal Regulations, 2011 CFR
2011-04-01
... have been damaged due to natural disasters (floods, hurricanes, tornadoes, etc.). (b) The Federal... 25 Indians 1 2011-04-01 2011-04-01 false What emergency or disaster assistance programs are... emergency or disaster assistance programs are available? (a) FHWA operates two emergency relief programs: (1...
25 CFR 170.921 - What emergency or disaster assistance programs are available?
Code of Federal Regulations, 2013 CFR
2013-04-01
... have been damaged due to natural disasters (floods, hurricanes, tornadoes, etc.). (b) The Federal... 25 Indians 1 2013-04-01 2013-04-01 false What emergency or disaster assistance programs are... emergency or disaster assistance programs are available? (a) FHWA operates two emergency relief programs: (1...
25 CFR 170.921 - What emergency or disaster assistance programs are available?
Code of Federal Regulations, 2014 CFR
2014-04-01
... have been damaged due to natural disasters (floods, hurricanes, tornadoes, etc.). (b) The Federal... 25 Indians 1 2014-04-01 2014-04-01 false What emergency or disaster assistance programs are... emergency or disaster assistance programs are available? (a) FHWA operates two emergency relief programs: (1...
25 CFR 170.921 - What emergency or disaster assistance programs are available?
Code of Federal Regulations, 2012 CFR
2012-04-01
... have been damaged due to natural disasters (floods, hurricanes, tornadoes, etc.). (b) The Federal... 25 Indians 1 2012-04-01 2011-04-01 true What emergency or disaster assistance programs are... emergency or disaster assistance programs are available? (a) FHWA operates two emergency relief programs: (1...
34 CFR 642.10 - Activities the Secretary assists under the Training Program.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Secretary assists under the Training Program. (a) A Training Program project trains the staff and leadership... 34 Education 3 2010-07-01 2010-07-01 false Activities the Secretary assists under the Training... (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION TRAINING PROGRAM FOR FEDERAL TRIO...
Animal-Assisted Stress Reduction Programs in Higher Education
ERIC Educational Resources Information Center
Haggerty, Julie M.; Mueller, Megan Kiely
2017-01-01
This study investigated the prevalence of increasingly popular animal-assisted stress relief programs at higher education institutions across the United States. Although research on animal-assisted programs is increasing, there is still a lack of information documenting implementation of these programs. Therefore, the purpose of this study was to…
75 FR 41397 - Asparagus Revenue Market Loss Assistance Payment Program
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-16
... Revenue Market Loss Assistance Payment Program AGENCY: Commodity Credit Corporation and Farm Service... to implement the new Asparagus Revenue Market Loss Assistance Payment (ALAP) Program authorized by the Food, Conservation, and Energy Act of 2008 (the 2008 Farm Bill). The purpose of the program is to...
Middle School Teachers' Perceptions of Computer-Assisted Reading Intervention Programs
ERIC Educational Resources Information Center
Bippert, Kelli; Harmon, Janis
2017-01-01
Middle schools often turn to computer-assisted reading intervention programs to improve student reading. The questions guiding this study are (a) in what ways are computer-assisted reading intervention programs utilized, and (b) what are teachers' perceptions about these intervention programs? Nineteen secondary reading teachers were interviewed…
The diffusion of a community-level HIV intervention for women: lessons learned and best practices.
King, Winifred; Nu'Man, Jeanette; Fuller, Talleria R; Brown, Mari; Smith, Shuenae; Howell, A Vyann; Little, Stacey; Patrick, Patricia; Glover, LaShon
2008-09-01
Abstract Early in the HIV/AIDS epidemic in the United States, relatively few women were diagnosed with HIV infection and AIDS. Today, the epidemic represents a growing and persistent health threat to women in the United States, especially young women and women of color. In 2005, the leading cause of HIV infection among African American women and Latinas was heterosexual contact. In addressing HIV prevention needs among women, community-level strategies are needed to increase consistent condom use by women and their partners and to change community norms to support safer sex behaviors. The Real AIDS Prevention Project (RAPP) is a community-based HIV prevention intervention for women and their partners. RAPP is based on a community mobilization model that involves a combination of activities, including street outreach, one-on-one discussions called stage-based encounters, role model stories, community networks, and small group activities. The objectives of RAPP are to increase consistent condom use by women and their partners and change community norms associated with perceptions of condom use and high-risk behaviors in an effort to make safer sex practice more acceptable. This paper describes the Centers for Disease Control and Prevention (CDC) Division of HIV/AIDS Prevention (DHAP) effort to nationally diffuse RAPP from March 2003 through May 2007 and lessons learned from that diffusion experience. The paper specifically discusses (1) collaborating and planning with researchers, (2) a diffusion needs assessment that was designed to assess prior implementation experiences among select agencies, (3) developing the intervention package, (4) developing and piloting training for community-based organizations (CBOs), (5) a rollout of national trainings for health departments and community-based organizations interested in implementing RAPP, and (6) ongoing quality assurance activities and the provision of technical assistance and support. RAPP has been proven effective in reducing HIV transmission risk behaviors and improving communication and negotiation skills necessary for African American women and Latinas to reduce their risk for HIV infection and improve their overall health status.
48 CFR 819.7110 - Developmental assistance.
Code of Federal Regulations, 2010 CFR
2010-10-01
... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS VA Mentor-Protégé Program 819.7110 Developmental assistance. The forms of developmental assistance a mentor can provide to a protégé include, but are not limited...
Employee assistance programs: an overview and suggested roles for psychiatrists.
Brill, P; Herzberg, J; Speller, J L
1985-07-01
Although employee assistance programs are rapidly becoming the predominant vehicle for the delivery of mental health services in occupational settings, few programs employ a psychiatrist on either a part-time or a full-time basis. After providing an overview of the need for, cost-effectiveness of, and current status of employee assistance programs, the authors draw on their own experiences with employee assistance programs to present four broad categories of roles the psychiatrist can assume in such programs: clinician, supervisor and educator, administrator, and organizational consultant. Problems encountered in these roles are also discussed.
Chiappone, Alethea; Smith, Teresa M; Estabrooks, Paul A; Rasmussen, Cristy Geno; Blaser, Casey; Yaroch, Amy L
2018-04-26
The National Early Care and Education Learning Collaboratives Project (ECELC) aims to improve best practices in early care and education (ECE) programs in topic areas of the Nutrition and Physical Activity Self-Assessment in Child Care (NAP SACC). Technical assistance is a component of the ECELC, yet its effect on outcomes is unclear. Beyond dose and duration of technical assistance, limited research exists on characteristics of technical assistance that contribute to outcomes. The objective of this study was to identify and describe technical assistance characteristics and explore associations with NAP SACC outcomes. We collected data from 10 collaboratives comprising 84 ECE programs in 2 states in 2015-2016. The objective of technical assistance was to support programs in improving best practices. Technical assistance was provided to programs via on-site, telephone, or email and was tailored to program needs. We used a mixed-methods design to examine associations between technical assistance and NAP SACC outcomes. We used multiple regression analysis to assess quantitative data and qualitative comparative analysis to determine necessary and sufficient technical assistance conditions supporting NAP SACC outcomes. We also conducted a document review to describe technical assistance that referred conditions identified by the qualitative comparative analysis. Regression analyses detected an inverse relationship between changes in NAP SACC scores and hours of technical assistance. No clear pattern emerged in the qualitative comparative analysis, leaving no necessary and sufficient conditions. However, the qualitative comparative analysis identified feedback as a potentially important component of technical assistance, whereas resource sharing and frequent email were characteristics that seemed to reduce the likelihood of improved outcomes. Email and resource sharing were considered primarily general information rather than tailored technical assistance. Technical assistance may be used in programs and made adaptable to program needs. The inclusion and evaluation of technical assistance, especially tailored approaches, is warranted for environmental interventions, including ECE settings.
Dental Assisting Education in California.
ERIC Educational Resources Information Center
California State Dept. of Education, Sacramento. Bureau of Industrial Education.
A survey of 22 dental assisting programs showed an average of 1,124 hours of instruction in dental assisting for 15 four-semester, 955 for three three-semester, and 1,042 for four two-semester programs. The average instructional hours for the four-semester programs were 48 in introduction to dental assisting, 179 in the life sciences, 221 in the…
ERIC Educational Resources Information Center
Tennessee Student Assistance Corp., Nashville.
The Tennessee Educational Loan Corporation and the Tennessee Student Assistance Agency have merged into a single state agency, the Tennessee Student Assistance Corporation, for the purpose of administering the state's student assistance programs. These are: (1) the Tuition Grant Program; (2) Guaranteed Student Loan Program; (3) Medical…
75 FR 18516 - Rhode Island; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-12
..., under the Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees. In addition, you are authorized to provide such other forms of assistance under Title V... (Category B), limited to direct Federal assistance, under the Public Assistance program. (The following...
28 CFR 42.503 - Discrimination prohibited.
Code of Federal Regulations, 2010 CFR
2010-07-01
... program or activity receiving Federal financial assistance. (b) Discriminatory actions prohibited. (1) A... program or activity receiving Federal financial assistance; (ii) Deny a qualified handicapped person an... program or activity receiving Federal financial assistance on the ground that other specialized aid...
RxHope: Patient Assistance Information
... FAQ Pharma Companies Below is a list current Patient Assistance Programs. Click on the first letter of ... V W X Y Z AbbVie Norvir Kaletra Patient Assistance Program AbbVie Patient Assistance Foundation AbbVie Patient ...
2014-08-14
The Assistant Secretary for Special Education and Rehabilitative Services announces a priority under the Assistive Technology Alternative Financing Program administered by the Rehabilitation Services Administration (RSA). The Assistant Secretary may use this priority for competitions in fiscal year (FY) 2014 and later years. This priority is designed to ensure that the Department funds high-quality assistive technology (AT) alternative financing programs (AFPs) that meet rigorous standards in order to enable individuals with disabilities to access and acquire assistive technology devices and services necessary to achieve education, community living, and employment goals.
76 FR 44025 - Missouri; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-22
... Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees..., under the Public Assistance program. The following Catalog of Federal Domestic Assistance Numbers (CFDA... Emergency Assistance Act, 42 U.S.C. 5121-5208 (the Stafford Act), as follows: I have determined that the...
77 FR 2989 - Massachusetts; Major Disaster and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-20
... Commonwealth. You are further authorized to provide snow assistance under the Public Assistance program in the...-grantees' regular employees. Consistent with the requirement that Federal assistance is supplemental, any... Counties for snow assistance under the Public Assistance program for any continuous 48-hour period during...
ERIC Educational Resources Information Center
National Commission for Employment Policy (DOL), Washington, DC.
This special report from the National Commission for Employment Policy on coordinating federal assistance programs for the economically disadvantaged contains two parts. Part 1 includes recommendations for improving public assistance coordination programs in general and employment and training programs in particular. Eight recommendations focus on…
24 CFR 905.120 - Penalties for slow obligation or expenditure of Capital Fund program assistance.
Code of Federal Regulations, 2011 CFR
2011-04-01
... expenditure of Capital Fund program assistance. 905.120 Section 905.120 Housing and Urban Development... INDIAN HOUSING, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT THE PUBLIC HOUSING CAPITAL FUND PROGRAM Capital Fund § 905.120 Penalties for slow obligation or expenditure of Capital Fund program assistance. In...
34 CFR 389.2 - Who is eligible for assistance under this program?
Code of Federal Regulations, 2010 CFR
2010-07-01
... 34 Education 2 2010-07-01 2010-07-01 false Who is eligible for assistance under this program? 389.2 Section 389.2 Education Regulations of the Offices of the Department of Education (Continued... CONTINUING EDUCATION PROGRAMS General § 389.2 Who is eligible for assistance under this program? Those...
ERIC Educational Resources Information Center
Chen, Chiu-Jung; Liu, Pei-Lin
2007-01-01
This study evaluated the effects of a personalized computer-assisted mathematics problem-solving program on the performance and attitude of Taiwanese fourth grade students. The purpose of this study was to determine whether the personalized computer-assisted program improved student performance and attitude over the nonpersonalized program.…
ERIC Educational Resources Information Center
Mississippi Research and Curriculum Unit for Vocational and Technical Education, State College.
This document, which is intended for use by community and junior colleges throughout Mississippi, contains curriculum frameworks for the course sequences in the medical assisting technology program. Presented in the introductory section are a description of the program and suggested course sequence. Section I lists baseline competencies, and…
1999-09-01
employment assistance programs ( EAPs ). To evaluate these programs , and to provide a demographic and employment-related profile of spouses of junior enlisted...spouse Employment Assistance Program ( EAP ) services, policies, and procedures. The Army, Navy, Marine Corps, and Air Force each offer separate yet...help wanted advertisements. Only 7% were found through the Employment Assistance Program ( EAP ). Spouses faced barriers in their efforts to enter or
30 CFR 795.1 - Scope and purpose.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR SMALL OPERATOR ASSISTANCE PERMANENT REGULATORY PROGRAM-SMALL OPERATOR ASSISTANCE PROGRAM § 795.1 Scope and purpose. This part comprises the Small Operator Assistance Program (SOAP) and establishes the procedures for...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-08-27
... DEPARTMENT OF AGRICULTURE Food and Nutrition Service Supplemental Nutrition Assistance Program (SNAP) Enhancing Retail Food Store Eligibility--Listening Sessions AGENCY: Food and Nutrition Service... for Information (RFI) published by FNS regarding Supplemental Nutrition Assistance Program (SNAP...
78 FR 8222 - Proposed Collection; Comment Request for Regulation Project
Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-05
... Employers' Qualified Educational Assistance Programs. DATES: Written comments should be received on or... INFORMATION: Title: Employers' Qualified Educational Assistance Programs. OMB Number: 1545-0768. Regulation... furnished to the employee pursuant to a qualified educational assistance program. This regulation requires...
78 FR 31535 - Assistive Technology Alternative Financing Program
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-24
... DEPARTMENT OF EDUCATION Assistive Technology Alternative Financing Program AGENCY: Office of Special Education and Rehabilitative Services, Department of Education. ACTION: Notice. Catalog of Federal... developed for the Assistive Technology (AT) Alternative Financing Program (AFP) in fiscal year (FY) 2012 to...
ERIC Educational Resources Information Center
Gray, Kelsey Farson; Eslami, Esa
2014-01-01
The Supplemental Nutrition Assistance Program (SNAP) serves as the foundation of America's national nutrition safety net. It is the nation's first line of defense against food insecurity and offers a powerful tool to improve nutrition among low-income individuals. SNAP is the largest of the 15 domestic food and nutrition assistance programs…
34 CFR 350.63 - What are the requirements of a grantee relative to the Client Assistance Program?
Code of Federal Regulations, 2010 CFR
2010-07-01
... Client Assistance Program? 350.63 Section 350.63 Education Regulations of the Offices of the Department... After an Award? § 350.63 What are the requirements of a grantee relative to the Client Assistance... representatives, of the availability and purposes of the Client Assistance Program (CAP) funded under the Act; and...
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 3 2010-01-01 2010-01-01 false Forwarding of applications for State grants for technical assistance, program assistance, and marketing. 455.134 Section 455.134 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION GRANT PROGRAMS FOR SCHOOLS AND HOSPITALS AND BUILDINGS OWNED BY UNITS OF LOCAL GOVERNMENT AND PUBLIC CARE INSTITUTIONS State...
Security Assistance Dependence - Wielding American Power
2002-12-09
national security objectives. One vehicle of this power brokering is the well-developed international security assistance program – oftentimes...incorrectly referred to exclusively as foreign military sales. There is nothing simple about the security assistance program as it has developed today...For the USG, there are many agencies influencing today’s security assistance program to execute complex, integrated tasks directly impacting U.S
Evaluating Quality of Life Programs: Summary of a Literature Review
1990-05-01
Employee Assistance Programs ( EAPs ) are contemporary innovations in the U.S. workplace. Few have been... employee -mover in the country and, as such, provides many services in the areas of reimbursement and relocation assistance . While relocation assistance ...personnel journals suggest that organizations must have adequate relocation assistance programs to limit the extent to which employees refuse moves (by
ERIC Educational Resources Information Center
Fung, Suk-chun
2017-01-01
A canine-assisted reading program, a form of animal-assisted intervention (AAI), is a goal-oriented program that incorporates trained animals--particularly canines--in formal human services. In recent decades, the positive effects of human-animal interaction in supporting the social, psychological, and physiological needs of humans have been…
Expanding undergraduate dietetic education through a health promotion internship program.
Rye, J A; Weston, C
1987-05-01
The Lifestyle Assistant Program is a health promotion internship offered by the University of Wisconsin-Stevens Point Health Service. Students majoring in health-related disciplines (e.g., dietetics) gain skills in promoting the six dimensions of wellness: social, occupational, spiritual, physical, intellectual, and emotional. Thirteen competencies provide the basis for training Lifestyle Assistants, who develop, market, present, and evaluate wellness sessions for the university and residential communities. Assistants earn academic credit or a wage. Of particular benefit to assistants majoring in dietetics are studying and operating a self-testing physical assessment unit, which approximates body composition, cardiovascular endurance, muscular strength, and flexibility; using a health hazard appraisal; assisting the University's Nutrition Task Force with its education campaign in the campus cafeterias; and presenting programs on popular nutrition topics (e.g., the athlete's diet). Program evaluation reveals that 84% of participants in programs conducted by assistants gained information of personal benefit. The Lifestyle Assistant competencies support The American Dietetic Association Plan IV minimum competencies in such areas as communication and education. The Lifestyle Assistant experience is in accordance with The American Dietetic Association's Dietetic Manpower Study recommendations: to provide student learning experiences in wellness programs and fitness settings.
Smith, Bryce D; Kalayil, Elizabeth J; Patel-Larson, Alpa; Chen, Brenda; Vaughan, Marla
2012-02-01
The Centers for Disease Control and Prevention (CDC), Division of HIV/AIDS Prevention (DHAP) conducted outcome monitoring studies on evidence-based interventions (EBIs) provided by CDC-funded community-based organizations (CBOs). Critical to the success of outcome monitoring was the ability of CBOs to recruit and retain clients in evaluation studies. Two EBIs, Video Opportunities for Innovative Condom Education and Safer Sex (VOICES/VOCES) and Healthy Relationships, were evaluated using repeated measure studies, which require robust follow-up retention rates to increase the validity and usefulness of the findings. The retention rates were high for both VOICES/VOCES CBOs (95.8% at 30 days and 91.1% at 120 days), and Healthy Relationships CBOs (89.5% at 90 days and 83.5% at 180 days). This paper presents an overview of the retention of clients, challenges to follow-up, and strategies developed by CBOs to achieve high retention rates. These strategies and rates are discussed within the context of the CBOs' target populations and communities. Published by Elsevier Ltd.
DoD Civilian Drug Abuse Testing Program
1988-08-23
employee assistance programs ( EAPs ). DoD Components must obtain approval of the ASD(HA) for specimen collection and laboratory testing... Employee . A DoD employee paid from appropriated funds. 2. Employee Assistance Programs ( EAPs ). DoD Component-based counseling programs that offer...Renumber Ś." to ř." Subparagraph E.5.a.(2), line 1. After "(2)" insert " Employee Assistance Programs " and enclose "
7 CFR 1700.34 - Assistance to High Energy Cost Rural Communities.
Code of Federal Regulations, 2010 CFR
2010-01-01
... Assistance to High Energy Cost Rural Communities. RUS, through the Electric Program, makes grants and loans to assist high energy cost rural communities. The Assistant Administrator, Electric Program, directs... 7 Agriculture 11 2010-01-01 2010-01-01 false Assistance to High Energy Cost Rural Communities...
13 CFR 313.3 - Overview of Community Trade Adjustment Assistance.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false Overview of Community Trade..., DEPARTMENT OF COMMERCE COMMUNITY TRADE ADJUSTMENT ASSISTANCE Participation in the Community Trade Adjustment Assistance Program § 313.3 Overview of Community Trade Adjustment Assistance. The Community TAA Program is...
13 CFR 313.3 - Overview of Community Trade Adjustment Assistance.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 13 Business Credit and Assistance 1 2014-01-01 2014-01-01 false Overview of Community Trade..., DEPARTMENT OF COMMERCE COMMUNITY TRADE ADJUSTMENT ASSISTANCE Participation in the Community Trade Adjustment Assistance Program § 313.3 Overview of Community Trade Adjustment Assistance. The Community TAA Program is...
77 FR 41193 - West Virginia; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-12
... Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees... Assistance program. The following Catalog of Federal Domestic Assistance Numbers (CFDA) are to be used [[Page... Emergency Assistance Act, 42 U.S.C. 5121-5207 (the Stafford Act), as follows: I have determined that the...
76 FR 44026 - Kansas; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-22
... Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees... Assistance program. The following Catalog of Federal Domestic Assistance Numbers (CFDA) are to be used for... Emergency Assistance Act, 42 U.S.C. 5121-5208 (the Stafford Act), as follows: I have determined that the...
7 CFR 1700.34 - Assistance to High Energy Cost Rural Communities.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 7 Agriculture 11 2013-01-01 2013-01-01 false Assistance to High Energy Cost Rural Communities... Assistance to High Energy Cost Rural Communities. RUS, through the Electric Program, makes grants and loans to assist high energy cost rural communities. The Assistant Administrator, Electric Program, directs...
7 CFR 1700.34 - Assistance to High Energy Cost Rural Communities.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 7 Agriculture 11 2011-01-01 2011-01-01 false Assistance to High Energy Cost Rural Communities... Assistance to High Energy Cost Rural Communities. RUS, through the Electric Program, makes grants and loans to assist high energy cost rural communities. The Assistant Administrator, Electric Program, directs...
Trial of the University Assistance Program for Alcohol Use Among Mandated Students*
Amaro, Hortensia; Ahl, Marilyn; Matsumoto, Atsushi; Prado, Guillermo; Mulé, Christina; Kemmemer, Amaura; Larimer, Mary E.; Masi, Dale; Mantella, Philomena
2009-01-01
Objective: The aim of this study was to investigate the effectiveness of a brief intervention for mandated students in the context of the University Assistance Program, a Student Assistance Program developed and modeled after workplace Employee Assistance Programs. Method: Participants were 265 (196 males and 69 females) judicially mandated college students enrolled in a large, urban university in the northeast United States. All participants were sanctioned by the university's judicial office for an alcohol- or drug-related violation. Participants were randomized to one of two intervention conditions (the University Assistance Program or services as usual) and were assessed at baseline and 3 and 6 months after intervention. Results: Growth curve analyses showed that, relative to services as usual, the University Assistance Program was more efficacious in reducing past-90-day weekday alcohol consumption and the number of alcohol-related consequences while increasing past-90-day use of protective behaviors and coping skills. No significant differences in growth trajectories were found between the two intervention conditions on past-90-day blood alcohol concentration, total alcohol consumption, or weekend consumption. Conclusions: The University Assistance Program may have a possible advantage over services as usual for mandated students. PMID:19538912
Trial of the university assistance program for alcohol use among mandated students.
Amaro, Hortensia; Ahl, Marilyn; Matsumoto, Atsushi; Prado, Guillermo; Mulé, Christina; Kemmemer, Amaura; Larimer, Mary E; Masi, Dale; Mantella, Philomena
2009-07-01
The aim of this study was to investigate the effectiveness of a brief intervention for mandated students in the context of the University Assistance Program, a Student Assistance Program developed and modeled after workplace Employee Assistance Programs. Participants were 265 (196 males and 69 females) judicially mandated college students enrolled in a large, urban university in the northeast United States. All participants were sanctioned by the university's judicial office for an alcohol- or drug-related violation. Participants were randomized to one of two intervention conditions (the University Assistance Program or services as usual) and were assessed at baseline and 3 and 6 months after intervention. Growth curve analyses showed that, relative to services as usual, the University Assistance Program was more efficacious in reducing past-90-day weekday alcohol consumption and the number of alcohol-related consequences while increasing past-90-day use of protective behaviors and coping skills. No significant differences in growth trajectories were found between the two intervention conditions on past-90-day blood alcohol concentration, total alcohol consumption, or weekend consumption. The University Assistance Program may have a possible advantage over services as usual for mandated students.
30 CFR 795.5 - Grant application procedures.
Code of Federal Regulations, 2010 CFR
2010-07-01
....5 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR SMALL OPERATOR ASSISTANCE PERMANENT REGULATORY PROGRAM-SMALL OPERATOR ASSISTANCE PROGRAM § 795.5 Grant application procedures. A State intending to administer a Small Operator Assistance Program under a grant from...
76 FR 18624 - Research, Technical Assistance and Training Programs: Notice of Final Circular
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-04
... to FTA Circular 6100.1D, Research and Technical Assistance Training Program: Application Instructions... DEPARTMENT OF TRANSPORTATION Federal Transit Administration Research, Technical Assistance and Training Programs: Notice of Final Circular AGENCY: Federal Transit Administration (FTA), DOT. ACTION...
10 CFR 455.131 - State ranking of grant applications.
Code of Federal Regulations, 2010 CFR
2010-01-01
...) For technical assistance programs, buildings shall be ranked in descending priority based upon the... all buildings covered by eligible applications for: (1) Technical assistance programs for units of local government and public care institutions and (2) Technical assistance programs for schools and...
45 CFR 95.707 - Equipment management and disposition.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 45 Public Welfare 1 2011-10-01 2011-10-01 false Equipment management and disposition. 95.707... ADMINISTRATION-GRANT PROGRAMS (PUBLIC ASSISTANCE, MEDICAL ASSISTANCE AND STATE CHILDREN'S HEALTH INSURANCE PROGRAMS) Equipment Acquired Under Public Assistance Programs § 95.707 Equipment management and disposition...
45 CFR 95.707 - Equipment management and disposition.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 45 Public Welfare 1 2010-10-01 2010-10-01 false Equipment management and disposition. 95.707... ADMINISTRATION-GRANT PROGRAMS (PUBLIC ASSISTANCE, MEDICAL ASSISTANCE AND STATE CHILDREN'S HEALTH INSURANCE PROGRAMS) Equipment Acquired Under Public Assistance Programs § 95.707 Equipment management and disposition...
75 FR 6263 - Biomass Crop Assistance Program
Federal Register 2010, 2011, 2012, 2013, 2014
2010-02-08
... Part II Department of Agriculture Commodity Credit Corporation 7 CFR Part 1450 Biomass Crop... RIN 0560-AH92 Biomass Crop Assistance Program AGENCY: Commodity Credit Corporation and Farm Service... to implement the new Biomass Crop Assistance Program (BCAP) authorized by the Food, Conservation, and...
Designing and Creating Computer-Assisted Instruction.
ERIC Educational Resources Information Center
McMeen, George R.
Designed to encourage the use of a defined methodology and careful planning in creating computer-assisted instructional programs, this paper describes the instructional design process, compares computer-assisted instruction (CAI) and programmed instruction (PI), and discusses pragmatic concerns in computer programming. Topics addressed include:…
New Impetus for Several General Assistance Programs.
ERIC Educational Resources Information Center
Reeder, Rick
1999-01-01
Describes 1999 federal funding to large general-assistance programs affecting small towns and rural areas (including Housing and Urban Development, federal disaster relief, rural extension activities, and Bureau of Indian Affairs assistance programs); increased funding for Empowerment Zones/Enterprise Communities; reauthorization of the Economic…
2010-03-01
ANALYSIS OF THE EFFECT OF THE NAVY’S TUITION ASSISTANCE PROGRAM : DO DISTANCE LEARNING CLASSES MAKE A DIFFERENCE? by Jeremy P. McLaughlin March...TYPE AND DATES COVERED Master’s Thesis 4. TITLE AND SUBTITLE A Statistical Analysis of the Effect of the Navy’s Tuition Assistance Program : Do...200 words) This thesis analyzes the impact of participation in the Navy’s Tuition Assistance (TA) program on the retention of first-term Navy
ERIC Educational Resources Information Center
Vernon, David H.
1989-01-01
The paper reviews and critiques the 13 existing (1987) law school assistance programs and proposes a national repayment-assistance debt-forgiveness program which would involve an income-contingent repayment "tax" coupled with an assurance to creditors of repayment by means of a "guarantee" or "insurance" fund. (DB)
ERIC Educational Resources Information Center
Mississippi Research and Curriculum Unit for Vocational and Technical Education, State College.
This document, which is intended for use by community and junior colleges throughout Mississippi, contains curriculum frameworks for the course sequences in the health care assistant program. Presented in the introductory section are a description of the program and suggested course sequence. Section I lists baseline competencies for the nurse…
ERIC Educational Resources Information Center
Samani, Ebrahim; Baki, Roselan; Razali, Abu Bakar
2014-01-01
Success in implementation of computer-assisted language learning (CALL) programs depends on the teachers' understanding of the roles of CALL programs in education. Consequently, it is also important to understand the barriers teachers face in the use of computer-assisted language learning (CALL) programs. The current study was conducted on 14…
34 CFR 389.2 - Who is eligible for assistance under this program?
Code of Federal Regulations, 2011 CFR
2011-07-01
... 34 Education 2 2011-07-01 2010-07-01 true Who is eligible for assistance under this program? 389.2 Section 389.2 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF... PROGRAMS General § 389.2 Who is eligible for assistance under this program? Those agencies and...
Misyak, Sarah; Ledlie Johnson, Meredith; McFerren, Mary; Serrano, Elena
2014-01-01
To explore Family Nutrition Program assistants' perception of farmers' markets and alternative agricultural practices for themselves and their clients. Cross-section design, survey of Virginia Expanded Food and Nutrition Education Program (NEP) and Supplemental Nutrition Assistance Program-Education Family Nutrition Program assistants (n = 52) working with limited-resource populations. Twenty-one percent to 55% of FNP assistants valued alternative agricultural practices, and only 5% to 8% of FNP assistants perceived that their clients did so. Benefits to shopping at farmers' markets included supporting local economies, and food price, quality, and safety. Barriers included lack of transportation, location/convenience, hours, and food prices. Assistants rated the benefits to shopping at farmers' markets similarly for themselves and their clients, but rated many of the barriers to shopping at farmers' markets as significantly lower (P < .05) for themselves than for their clients. Future assistant trainings should address the connection between agriculture and health, and how to overcome barriers to shopping at farmers' markets for their clients. Copyright © 2014 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.
Technical assistance for hazardous-waste reduction
DOE Office of Scientific and Technical Information (OSTI.GOV)
Thompson, F.M.; McComas, C.A.
1987-12-01
Minnesota's Waste Management Board has established, developed, and funded the Minnesota Technical Assistance Program (MnTAP). The MnTAP programs offers technical assistance to generators of hazardous waste by offering telephone and onsite consultation, a waste reduction resource bank, information dissemination, a student intern program, and research awards for waste reduction projects. The program has completed three years of successful operation. The increasing interest in and use of MnTAP's services by hazardous-waste generators has justified the belief that state technical assistance programs have an important role to play in helping generators to reduce their waste production.
76 FR 55000 - Notice of Agricultural Management Assistance Organic Certification Cost-Share Program
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-06
...] Notice of Agricultural Management Assistance Organic Certification Cost-Share Program AGENCY... Departments of Agriculture for the Agricultural Management Assistance Organic Certification Cost-Share Program... organic certification cost-share funds. The AMS has allocated $1.5 million for this organic certification...
78 FR 5164 - Notice of Agricultural Management Assistance Organic Certification Cost-Share Program
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-24
...] Notice of Agricultural Management Assistance Organic Certification Cost-Share Program AGENCY... Departments of Agriculture for the Agricultural Management Assistance Organic Certification Cost-Share Program... organic certification cost-share funds. The AMS has allocated $1.425 million for this organic...
Federal Student Assistance and Categorical Programs. 1981 Edition.
ERIC Educational Resources Information Center
Balz, Frank J.
The fourth edition of analyses of selected federal student assistance and categorical programs prepared by the National Institute of Independent Colleges and Universities is presented. Sections include: (1) federal student assistance--undergraduate programs (Pell Grants, Supplemental Educational Opportunity Grants, State Student Incentive Grants,…
45 CFR 95.701 - Purpose and scope of subpart.
Code of Federal Regulations, 2010 CFR
2010-10-01
... requirements for the management and disposition of equipment whose costs are claimed for Federal financial... ADMINISTRATION-GRANT PROGRAMS (PUBLIC ASSISTANCE, MEDICAL ASSISTANCE AND STATE CHILDREN'S HEALTH INSURANCE PROGRAMS) Equipment Acquired Under Public Assistance Programs § 95.701 Purpose and scope of subpart. (a...
45 CFR 95.701 - Purpose and scope of subpart.
Code of Federal Regulations, 2011 CFR
2011-10-01
... requirements for the management and disposition of equipment whose costs are claimed for Federal financial... ADMINISTRATION-GRANT PROGRAMS (PUBLIC ASSISTANCE, MEDICAL ASSISTANCE AND STATE CHILDREN'S HEALTH INSURANCE PROGRAMS) Equipment Acquired Under Public Assistance Programs § 95.701 Purpose and scope of subpart. (a...
40 CFR 52.2307 - Small business assistance program.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Small business assistance program. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Texas § 52.2307 Small business... implement a Small Business Stationary Source Technical and Environmental Compliance Assistance Program to...
40 CFR 52.1935 - Small business assistance program.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 4 2010-07-01 2010-07-01 false Small business assistance program. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oklahoma § 52.1935 Small business... implement a Small Business Stationary Source Technical and Environmental Compliance Assistance Program to...
40 CFR 52.1935 - Small business assistance program.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 4 2014-07-01 2014-07-01 false Small business assistance program. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oklahoma § 52.1935 Small business... implement a Small Business Stationary Source Technical and Environmental Compliance Assistance Program to...
40 CFR 52.2307 - Small business assistance program.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 5 2013-07-01 2013-07-01 false Small business assistance program. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Texas § 52.2307 Small business... implement a Small Business Stationary Source Technical and Environmental Compliance Assistance Program to...
40 CFR 52.1935 - Small business assistance program.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 4 2011-07-01 2011-07-01 false Small business assistance program. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oklahoma § 52.1935 Small business... implement a Small Business Stationary Source Technical and Environmental Compliance Assistance Program to...
40 CFR 52.2307 - Small business assistance program.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 5 2012-07-01 2012-07-01 false Small business assistance program. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Texas § 52.2307 Small business... implement a Small Business Stationary Source Technical and Environmental Compliance Assistance Program to...
40 CFR 52.2307 - Small business assistance program.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 5 2014-07-01 2014-07-01 false Small business assistance program. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Texas § 52.2307 Small business... implement a Small Business Stationary Source Technical and Environmental Compliance Assistance Program to...
40 CFR 52.1935 - Small business assistance program.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 4 2012-07-01 2012-07-01 false Small business assistance program. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oklahoma § 52.1935 Small business... implement a Small Business Stationary Source Technical and Environmental Compliance Assistance Program to...
40 CFR 52.2307 - Small business assistance program.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 4 2011-07-01 2011-07-01 false Small business assistance program. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Texas § 52.2307 Small business... implement a Small Business Stationary Source Technical and Environmental Compliance Assistance Program to...
40 CFR 52.1935 - Small business assistance program.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 4 2013-07-01 2013-07-01 false Small business assistance program. 52... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS (CONTINUED) Oklahoma § 52.1935 Small business... implement a Small Business Stationary Source Technical and Environmental Compliance Assistance Program to...
24 CFR 582.100 - Program component descriptions.
Code of Federal Regulations, 2011 CFR
2011-04-01
... Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR COMMUNITY PLANNING AND DEVELOPMENT, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT COMMUNITY FACILITIES SHELTER PLUS CARE Assistance Provided § 582.100 Program component descriptions. (a) Tenant-based rental assistance (TRA). Tenant-based rental assistance provides...
30 CFR 795.11 - Assistance funding.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR SMALL OPERATOR ASSISTANCE PERMANENT REGULATORY PROGRAM-SMALL OPERATOR ASSISTANCE PROGRAM § 795.11 Assistance... eligible small operators if available funds are less than those required to provide the services pursuant...
Code of Federal Regulations, 2011 CFR
2011-07-01
... ASSISTANCE Financial Assistance for the National Estuary Program § 35.9010 Definitions. Aggregate costs. The... the estuary. Annual work plan. The plan, developed by the Management Conference each year, which... an estuary in the NEP. National Program Assistance Agreements. Assistance Agreements approved by the...
Code of Federal Regulations, 2014 CFR
2014-07-01
... ASSISTANCE Financial Assistance for the National Estuary Program § 35.9010 Definitions. Aggregate costs. The... the estuary. Annual work plan. The plan, developed by the Management Conference each year, which... an estuary in the NEP. National Program Assistance Agreements. Assistance Agreements approved by the...
Code of Federal Regulations, 2013 CFR
2013-07-01
... ASSISTANCE Financial Assistance for the National Estuary Program § 35.9010 Definitions. Aggregate costs. The... the estuary. Annual work plan. The plan, developed by the Management Conference each year, which... an estuary in the NEP. National Program Assistance Agreements. Assistance Agreements approved by the...
Code of Federal Regulations, 2012 CFR
2012-07-01
... ASSISTANCE Financial Assistance for the National Estuary Program § 35.9010 Definitions. Aggregate costs. The... the estuary. Annual work plan. The plan, developed by the Management Conference each year, which... an estuary in the NEP. National Program Assistance Agreements. Assistance Agreements approved by the...
Code of Federal Regulations, 2010 CFR
2010-07-01
... ASSISTANCE Financial Assistance for the National Estuary Program § 35.9010 Definitions. Aggregate costs. The... the estuary. Annual work plan. The plan, developed by the Management Conference each year, which... an estuary in the NEP. National Program Assistance Agreements. Assistance Agreements approved by the...
ERIC Educational Resources Information Center
Behr, Shirley K.; And Others
A project to provide technical assistance to staffs of two demonstration programs for preschool handicapped children and their families is described. The focus was technical assistance developed and exercised by the Technical Assistance Development System (TADS), which assisted in the development of the Handicapped Children's Early Education…
Weiler, R M; Pigg, R M
2000-11-01
Client or customer satisfaction surveys assess the perceived quality of programs, products, services, and employee performance. Such assessments prove beneficial for evaluation and planning purposes. This survey examined the satisfaction of clients using the programs, services, and technical assistance provided through the Coordinated School Health Program Office (CSHPO) in the Florida Department of Education. Using the 42-item Client Satisfaction Survey, data were collected in summer 1999 from 300 of 574 clients (52.3%) who attended training sessions or sought technical assistance from CSHPO during 1996-1999. More than two-thirds (67.2%) of clients rated the training program as "very good" or "excellent" at increasing their understanding about the concept of a coordinated school health program. Overall, 69.7% of clients rated the training programs they attended as "very good" or "excellent." Resource materials and staff effectiveness rated positively as well. Findings confirmed client satisfaction with CSHPO's training programs, technical assistance, and staff. Information obtained through the client satisfaction survey can be used by CSHPO to assist in future program planning and resource allocations.
Smith, Teresa M.; Estabrooks, Paul A.; Rasmussen, Cristy Geno; Blaser, Casey; Yaroch, Amy L
2018-01-01
Purpose and Objectives The National Early Care and Education Learning Collaboratives Project (ECELC) aims to improve best practices in early care and education (ECE) programs in topic areas of the Nutrition and Physical Activity Self-Assessment in Child Care (NAP SACC). Technical assistance is a component of the ECELC, yet its effect on outcomes is unclear. Beyond dose and duration of technical assistance, limited research exists on characteristics of technical assistance that contribute to outcomes. The objective of this study was to identify and describe technical assistance characteristics and explore associations with NAP SACC outcomes. Intervention Approach We collected data from 10 collaboratives comprising 84 ECE programs in 2 states in 2015–2016. The objective of technical assistance was to support programs in improving best practices. Technical assistance was provided to programs via on-site, telephone, or email and was tailored to program needs. Evaluation Methods We used a mixed-methods design to examine associations between technical assistance and NAP SACC outcomes. We used multiple regression analysis to assess quantitative data and qualitative comparative analysis to determine necessary and sufficient technical assistance conditions supporting NAP SACC outcomes. We also conducted a document review to describe technical assistance that referred conditions identified by the qualitative comparative analysis. Results Regression analyses detected an inverse relationship between changes in NAP SACC scores and hours of technical assistance. No clear pattern emerged in the qualitative comparative analysis, leaving no necessary and sufficient conditions. However, the qualitative comparative analysis identified feedback as a potentially important component of technical assistance, whereas resource sharing and frequent email were characteristics that seemed to reduce the likelihood of improved outcomes. Email and resource sharing were considered primarily general information rather than tailored technical assistance. Implications for Public Health Technical assistance may be used in programs and made adaptable to program needs. The inclusion and evaluation of technical assistance, especially tailored approaches, is warranted for environmental interventions, including ECE settings. PMID:29704371
Peer-Assisted Learning/Literacy Strategies. What Works Clearinghouse Intervention Report
ERIC Educational Resources Information Center
What Works Clearinghouse, 2012
2012-01-01
"Peer-Assisted Learning Strategies" and a similar program known as "Peer-Assisted Literacy Strategies" are peer-tutoring programs that supplement the primary reading curriculum (Fuchs, Fuchs, Kazdan, & Allen, 1999; Mathes & Babyak, 2001). This review uses the acronym "PALS" to encompass both programs and their…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-16
... for the Supplemental Nutrition Assistance Program Quality Control Reviews AGENCY: Food and Nutrition... Nutrition Assistance Program's Quality Control Reviews. DATES: Written comments must be received on or...: Worksheet for the Supplemental Nutrition Assistance Program's (SNAP) Quality Control Reviews. Form Number...
75 FR 68811 - Recovery Publication, P-395, Fire Management Assistance Grant Program (FMAGP) Guide
Federal Register 2010, 2011, 2012, 2013, 2014
2010-11-09
... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency [Docket ID FEMA-2010-0066] Recovery Publication, P-395, Fire Management Assistance Grant Program (FMAGP) Guide AGENCY: Federal... Emergency Management Agency (FEMA) is accepting comments on the Fire Management Assistance Grant Program...
76 FR 6313 - Asparagus Revenue Market Loss Assistance Payment Program
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-04
... Revenue Market Loss Assistance Payment Program AGENCY: Commodity Credit Corporation and Farm Service Agency, USDA. ACTION: Final rule. SUMMARY: This rule implements the Asparagus Revenue Market Loss Assistance Payment (ALAP) Program authorized by the Food, Conservation and Energy Act of 2008 (the 2008 Farm...
An Analysis of the Neighborhood Impacts of a Mortgage Assistance Program: A Spatial Hedonic Model
ERIC Educational Resources Information Center
Di, Wenhua; Ma, Jielai; Murdoch, James C.
2010-01-01
Down payment or closing cost assistance is an effective program in addressing the wealth constraints of low-and moderate-income homebuyers. However, the spillover effect of such programs on the neighborhood is unknown. This paper estimates the impact of the City of Dallas Mortgage Assistance Program (MAP) on nearby home values using a hedonic…
Grob, Rachel; Schlesinger, Mark; Davis, Sarah; Cohen, Deborah; Lapps, Joshua
2013-02-01
The Affordable Care Act provides support for state-run consumer assistance programs to help privately insured consumers who experience problems with their coverage. Its provisions signify the first national commitment to such assistance and to using cases aggregated by these state programs to inform policy. We interviewed state-level administrators and analyzed program documents to assess whether federal support for state-run consumer assistance programs achieved certain goals. We found that some federally supported programs made substantial progress in supporting and empowering patients by reorienting state agencies to become active advocates for their citizens. Yet progress across the country was inconsistent, and there was little evidence that programs addressed systemic problems experienced by consumers. On balance, the consumer assistance provisions of health care reform do not yet ensure protection for all privately insured Americans because of uneven implementation-a problem likely to be of further concern as coverage is expanded and health insurance exchanges come on line in 2014. At the same time, the demonstrated impact of consumer assistance programs in the most innovative states is arguably a useful "proof of concept" for this young federal program.
75 FR 25103 - Tree Assistance Program
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-07
... 1416 RIN 0560-AH96 Tree Assistance Program AGENCY: Farm Service Agency and Commodity Credit Corporation, USDA. ACTION: Final rule. SUMMARY: This rule implements specific requirements for the Tree Assistance... provides disaster assistance to eligible orchardists and nursery tree growers to replant or rehabilitate...
75 FR 1811 - Agency Information Collection Activities: Proposed Collection; Comments Requested
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-13
... Justice Assistance Application Form: Public Safety Officers' Educational Assistance. The Department of Justice, Office of Justice Programs, Bureau of Justice Assistance, will be submitting the following... DEPARTMENT OF JUSTICE Office of Justice Programs; Bureau of Justice Assistance [OMB Number 1121...
Dental Assisting Program Guide.
ERIC Educational Resources Information Center
Georgia Univ., Athens. Dept. of Vocational Education.
This program guide contains the standard dental assisting curriculum for technical institutes in Georgia. The curriculum encompasses the minimum competencies required for entry-level dental assistants, and includes job skills in the technical areas of preventive dentistry; four-handed dentistry; chairside assisting with emphasis in diagnostics,…
10 CFR 707.6 - Employee assistance, education, and training.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 4 2010-01-01 2010-01-01 false Employee assistance, education, and training. 707.6....6 Employee assistance, education, and training. Contractor programs shall include the following or appropriate alternatives: (a) Employee assistance programs emphasizing preventive services, education, short...
76 FR 60850 - Delaware; Emergency and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-30
..., under the Public Assistance program. This assistance excludes regular time costs for subgrantees' regular employees. Consistent with the requirement that Federal assistance is supplemental, any Federal... program. (The following Catalog of Federal Domestic Assistance Numbers (CFDA) are to be used for reporting...
1985-01-01
jurisdiction over all U.S. DOD personnel and their dependents in Turkey. Security Assistance The U.S. Security Assistance Program in Turkey consists of a...variety of related activities. a. The Foreign Military Sales (FMS) and Military Assistance Pro- gram (MAP). These programs are designed to help...training. The FY85 IMET program for Turkey is about $3.1 million. [An expanded discussion of these security assistance activities is provided in the
Effective Delivery of Transition Assistance to Air Force Members Leaving the Service.
1997-03-01
Members Leaving the Service AF504R1/MARCH 1997 Executive Summary BACKGROUND Congress established the Transition Assistance Program (TAP) for the armed...forces in the National Defense Authorization Act for Fiscal Year 1991 (Public Law 101-510). This program assists military members and their families...other FSC program managers are responsible for delivering some transition services, espe- cially relocation assistance , financial counseling, and
United States Air Force Statistical Digest, Fiscal Year 1960. Fifteenth Edition
1960-09-30
USAF CIVILIAN EMPLOYEES IN SALARIED AND WAGE BOARD GROUPS EMPLOYED UNDER MILITARY , ASSISTANCE PROGRAM (MAP), AT END OF QUARTER - FY (Previous year...provide summary data on all aspects of the Mlli_ 165 tary Assistance program administered by the Air Force. The data were compiled from progress reports...Military Assistance . MAP AIRCRAFT - Aircraft in foreign countries provided by the USAF under Military Assistance Program . AIRCRAFT ATTRITION - Aircraft
ERIC Educational Resources Information Center
Litvak, Simi; And Others
This executive summary reviews results of a survey of 154 publicly-funded programs providing personal assistance services to disabled individuals. Introductory chapters identify the need for a national personal assistance program and policy, the concept of personal assistance and attendant services, the potential user population, and U.S. sources…
40 CFR 52.1690 - Small business technical and environmental compliance assistance program.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) New York § 52.1690 Small business technical and environmental compliance assistance program. On January 11, 1993, the New York State Department of Environmental Conservation submitted a plan for the... Assistance Program for incorporation in the New York state implementation plan. This plan meets the...
40 CFR 52.2732 - Small business technical and environmental compliance assistance program.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (CONTINUED) Puerto Rico § 52.2732 Small business technical and environmental compliance assistance program. On November 16, 1992, the Puerto Rico Environmental Quality Board submitted a plan for the... Assistance Program for incorporation in the Puerto Rico state implementation plan. This plan meets the...
40 CFR 52.2732 - Small business technical and environmental compliance assistance program.
Code of Federal Regulations, 2011 CFR
2011-07-01
... (CONTINUED) Puerto Rico § 52.2732 Small business technical and environmental compliance assistance program. On November 16, 1992, the Puerto Rico Environmental Quality Board submitted a plan for the... Assistance Program for incorporation in the Puerto Rico state implementation plan. This plan meets the...
40 CFR 52.2732 - Small business technical and environmental compliance assistance program.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) Puerto Rico § 52.2732 Small business technical and environmental compliance assistance program. On November 16, 1992, the Puerto Rico Environmental Quality Board submitted a plan for the... Assistance Program for incorporation in the Puerto Rico state implementation plan. This plan meets the...
Science CAP: Curriculum Assistance Program. [Multimedia.
ERIC Educational Resources Information Center
DEMCO, Inc., Madison, WI.
Science Curriculum Assistance Program (Science CAP(TM)) is a multimedia package developed to create a model for preserving classroom science activities that can be shared and customized by teachers. This program is designed to assist teachers in preparing classroom science activities for grades five through eight, and to foster an environment of…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-16
... Information; Centers for Independent Living Program--Training and Technical Assistance; Notice Inviting... Training and Technical Assistance Project. Program Authority: 29 U.S.C. 796f(b); American Recovery and... Independent Living Program--Training and Technical Assistance--CFDA Number 84.400B must be submitted...
78 FR 8690 - Notice of Request for Revision of Information Collections
Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-06
.... 5310--Capital Assistance Program for Elderly Persons and Persons with Disabilities and Section 5311... [email protected] . 49 U.S.C. 5310--Capital Assistance Program for Elderly Persons and Persons with... U.S.C. 5310--Capital Assistance Program for Elderly Persons and Persons with Disabilities and...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-12
...,'' to identify and address any major civil rights impacts the rule might have on minorities, women, and... Nutrition Assistance Program: Civil Rights Protections for SNAP Households AGENCY: Food and Nutrition... Nutrition Assistance Program (SNAP) regulations that secure civil rights protections for SNAP households and...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-15
... With Changes; State Criminal Alien Assistance Program ACTION: 30-day notice of information collection... collection expire. (2) The title of the form/collection: State Criminal Alien Assistance Program. (3) The... Criminal Alien Assistance Program (SCAAP) with the Bureau of Immigration and Customs Enforcement (ICE), and...
76 FR 20044 - Agency Information Collection Activities: Proposed Collection; Comments Requested
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-11
... Form: State Criminal Alien Assistance Program. The Department of Justice (DOJ), Office of Justice... currently approved collection. (2) The title of the form/collection: State Criminal Alien Assistance Program... Section 130002(b) as amended in 1996, BJA administers the State Criminal Alien Assistance Program (SCAAP...
13 CFR 121.401 - What procurement programs are subject to size determinations?
Code of Federal Regulations, 2010 CFR
2010-01-01
... program, the Women-Owned Small Business (WOSB) Federal Contract Assistance Procedures, SBA's Service... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false What procurement programs are subject to size determinations? 121.401 Section 121.401 Business Credit and Assistance SMALL BUSINESS...
49 CFR 613.300 - Coordination of Federal and federally assisted programs and projects.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 7 2012-10-01 2012-10-01 false Coordination of Federal and federally assisted programs and projects. 613.300 Section 613.300 Transportation Other Regulations Relating to Transportation... Coordination of Federal and Federally Assisted Programs and Projects § 613.300 Coordination of Federal and...
49 CFR 266.9 - Federal/State share.
Code of Federal Regulations, 2010 CFR
2010-10-01
... salaries for State public employees working in the State Rail Service Assistance Program, shall be... of the objectives of the Rail Service Assistance Program; (iii) Be provided for in the approved grant... Rail Service Assistance Program is 80 percent, with the exception that the Federal share of payments to...
Guide to Selected Federal Assistance Programs for Undergraduate Students.
ERIC Educational Resources Information Center
Stedman, Jim; Scott, Marcia
Information is provided on 14 federal programs providing financial assistance to undergraduate students in universities, colleges, and vocational/technical schools. The programs provide three different types of assistance: grants (or scholarships), loans, and job earnings. Grants and scholarships do not have to be repaid, but loans do. Some of the…
42 CFR 457.810 - Premium assistance programs: Required protections against substitution.
Code of Federal Regulations, 2012 CFR
2012-10-01
..., must provide the protections against substitution of CHIP coverage for coverage under group health... under premium assistance programs must not be greater than the cost of other CHIP coverage for these... of coverage for children under premium assistance programs to the cost of other CHIP coverage for...
42 CFR 457.810 - Premium assistance programs: Required protections against substitution.
Code of Federal Regulations, 2010 CFR
2010-10-01
..., must provide the protections against substitution of CHIP coverage for coverage under group health... under premium assistance programs must not be greater than the cost of other CHIP coverage for these... of coverage for children under premium assistance programs to the cost of other CHIP coverage for...
42 CFR 457.810 - Premium assistance programs: Required protections against substitution.
Code of Federal Regulations, 2011 CFR
2011-10-01
..., must provide the protections against substitution of CHIP coverage for coverage under group health... under premium assistance programs must not be greater than the cost of other CHIP coverage for these... of coverage for children under premium assistance programs to the cost of other CHIP coverage for...
42 CFR 457.810 - Premium assistance programs: Required protections against substitution.
Code of Federal Regulations, 2013 CFR
2013-10-01
..., must provide the protections against substitution of CHIP coverage for coverage under group health... under premium assistance programs must not be greater than the cost of other CHIP coverage for these... of coverage for children under premium assistance programs to the cost of other CHIP coverage for...
34 CFR 370.1 - What is the Client Assistance Program (CAP)?
Code of Federal Regulations, 2010 CFR
2010-07-01
... 34 Education 2 2010-07-01 2010-07-01 false What is the Client Assistance Program (CAP)? 370.1 Section 370.1 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION CLIENT ASSISTANCE PROGRAM General...
Facts on Employee Assistance Programs. Clearinghouse Fact Sheet.
ERIC Educational Resources Information Center
Desmond, Thomas C.
Employee Assistance Programs (EAPs) offer employees confidential, professional assistance for the kinds of personal problems that adversely affect their lives and their jobs. These programs started when acute worker shortages during World War II, coupled with the successes of Alcoholic Anonymous, prompted some companies in the 1940s to develop…
Employee Assistance Programs: Effective Tools for Counseling Employees.
ERIC Educational Resources Information Center
Kraft, Ed
1991-01-01
College employee assistance program designs demonstrate the varied needs of a workforce. Whatever the model, the helping approach remains to (1) identify problem employees through performance-related issues; (2) refer them to the assistance program for further intervention; and (3) follow up with employee and supervisor to ensure a successful…
Student Assistance Programs: New Approaches for Reducing Adolescent Substance Abuse.
ERIC Educational Resources Information Center
Moore, David D.; Forster, Jerald R.
1993-01-01
Describes school-based Student Assistance Programs (SAPs), which are designed to reduce adolescents' substance abuse. Notes that SAPs, modeled after Employee Assistance Programs in workplace, are identifying, assessing, referring, and managing cases of substance-abusing students. Sees adoption of SAP model as accelerating in response to growing…
48 CFR 229.170 - Reporting of foreign taxation on U.S. assistance programs.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Reporting of foreign taxation on U.S. assistance programs. 229.170 Section 229.170 Federal Acquisition Regulations System... General 229.170 Reporting of foreign taxation on U.S. assistance programs. ...
38 CFR 21.3002 - Administration of Survivors' and Dependents' Educational Assistance Program.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Administration of Survivors' and Dependents' Educational Assistance Program. Subpart D of this part applies to... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Administration of Survivors' and Dependents' Educational Assistance Program. 21.3002 Section 21.3002 Pensions, Bonuses, and...
38 CFR 21.3002 - Administration of Survivors' and Dependents' Educational Assistance Program.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Administration of Survivors' and Dependents' Educational Assistance Program. Subpart D of this part applies to... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Administration of Survivors' and Dependents' Educational Assistance Program. 21.3002 Section 21.3002 Pensions, Bonuses, and...
Medical Assisting Program Guide.
ERIC Educational Resources Information Center
Georgia Univ., Athens. Dept. of Vocational Education.
This guide presents the standard curriculum for technical institutes in Georgia. The curriculum addresses the minimum competencies for a medical assisting program. The program guide is designed to relate primarily to the development of those skills needed by individuals in the medical assisting field, such as medical law and ethics, typing,…
48 CFR 229.170 - Reporting of foreign taxation on U.S. assistance programs.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Reporting of foreign taxation on U.S. assistance programs. 229.170 Section 229.170 Federal Acquisition Regulations System... General 229.170 Reporting of foreign taxation on U.S. assistance programs. ...
76 FR 21774 - Wisconsin; Major Disaster and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-18
... protective measures, including snow assistance, under the Public Assistance program for any continuous 48... warranted. This assistance excludes regular time costs for the sub-grantees' regular employees. Consistent..., under the Public Assistance program for any continuous 48-hour period during or proximate to the...
Fashion Production and Management Program Guide.
ERIC Educational Resources Information Center
Georgia Univ., Athens. Div. of Vocational Education.
This program guide presents the standard fashion production and management curriculum for technical institutes in Georgia. It is designed to relate primarily to the development of those skills needed to become a qualified alterationist, clothing design assistant, home textiles assistant, fashion management assistant, or tailoring assistant. A…
24 CFR 891.175 - Technical assistance.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Technical assistance. 891.175... Requirements § 891.175 Technical assistance. For purposes of the Section 202 Program and the Section 811 Program, the Secretary shall make available appropriate technical assistance to assure that applicants...
10 CFR 905.40 - Technical assistance.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 4 2010-01-01 2010-01-01 false Technical assistance. 905.40 Section 905.40 Energy DEPARTMENT OF ENERGY ENERGY PLANNING AND MANAGEMENT PROGRAM Energy Services § 905.40 Technical assistance. Western shall establish a program that provides technical assistance to customers to conduct integrated...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Conger, Robin L.; Spanner, Gary E.
2011-11-02
The businesses that have utilized PNNL's Technology Assistance Program were sent a survey to solicit feedback about the program and to determine what, if any, outcomes resulted from the assistance provided. As part of its small business outreach, Pacific Northwest National Laboratory (PNNL) offers technology assistance to businesses with fewer than 500 employees throughout the nation and to businesses of any size in the 2 counties that contain the Hanford site. Upon request, up to 40 staff-hours of a researcher's time can be provided to address technology issues at no charge to the requesting firm. During FY 2011, PNNL completedmore » assistance for 54 firms. Topics of the technology assistance covered a broad range, including environment, energy, industrial processes, medical, materials, computers and software, and sensors. In FY 2011, PNNL's Technology Assistance Program (TAP) was funded by PNNL Overheads. Over the past 16 years, the Technology Assistance Program has received total funding of nearly $2.8 million from several federal and private sources.« less
The Federal Voting Assistance Program: Refocusing and Reorganizing for the Road Ahead
2015-12-16
Assistance Program (FVAP) admin-isters the Uniformed and Overseas Citizens Absentee Voting Act (UOCAVA)1 and helps uniformed-service members and other U.S...more effectively within the system. FVAP Assistance Options for Uniformed and Overseas Citizens Absentee Voting Act Voters Assistance seeker
34 CFR 692.1 - What is the Leveraging Educational Assistance Partnership?
Code of Federal Regulations, 2013 CFR
2013-07-01
... (LEAP) Program assists States in providing grants and work-study assistance to eligible students who attend institutions of higher education and have substantial financial need. The work-study assistance is provided through campus-based community service work learning study programs, hereinafter referred to as...
34 CFR 692.1 - What is the Leveraging Educational Assistance Partnership?
Code of Federal Regulations, 2012 CFR
2012-07-01
... (LEAP) Program assists States in providing grants and work-study assistance to eligible students who attend institutions of higher education and have substantial financial need. The work-study assistance is provided through campus-based community service work learning study programs, hereinafter referred to as...
34 CFR 692.1 - What is the Leveraging Educational Assistance Partnership?
Code of Federal Regulations, 2011 CFR
2011-07-01
... (LEAP) Program assists States in providing grants and work-study assistance to eligible students who attend institutions of higher education and have substantial financial need. The work-study assistance is provided through campus-based community service work learning study programs, hereinafter referred to as...
34 CFR 692.1 - What is the Leveraging Educational Assistance Partnership?
Code of Federal Regulations, 2014 CFR
2014-07-01
... (LEAP) Program assists States in providing grants and work-study assistance to eligible students who attend institutions of higher education and have substantial financial need. The work-study assistance is provided through campus-based community service work learning study programs, hereinafter referred to as...
24 CFR 880.603 - Selection and admission of assisted tenants.
Code of Federal Regulations, 2012 CFR
2012-04-01
... PERSONS WITH DISABILITIES PROGRAM) SECTION 8 HOUSING ASSISTANCE PAYMENTS PROGRAM FOR NEW CONSTRUCTION Management § 880.603 Selection and admission of assisted tenants. (a) Application. The owner must accept... concerning deferral of termination of assistance. (Approved by the Office of Management and Budget under...
24 CFR 880.603 - Selection and admission of assisted tenants.
Code of Federal Regulations, 2013 CFR
2013-04-01
... PERSONS WITH DISABILITIES PROGRAM) SECTION 8 HOUSING ASSISTANCE PAYMENTS PROGRAM FOR NEW CONSTRUCTION Management § 880.603 Selection and admission of assisted tenants. (a) Application. The owner must accept... concerning deferral of termination of assistance. (Approved by the Office of Management and Budget under...
Training Students as Technology Assistants.
ERIC Educational Resources Information Center
Onishi, Esther; Peto, Erica
1996-01-01
Describes a program where fifth and sixth graders are trained as school technology assistants. The childrens' duties include installation of software, making minor repairs, cleaning computer equipment, and assisting teachers and students. Outlines components of the program, lists forms the assistants use and skills they are taught, and provides…
75 FR 9426 - Maryland; Major Disaster and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-02
... measures (Category B) under the Public Assistance program in the designated areas. You are further authorized to provide snow assistance under the Public Assistance program for any continuous 48-hour period... assistance excludes regular time costs for the sub-grantees' regular employees. Consistent with the...
75 FR 11903 - Nebraska; Major Disaster and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-12
... protective measures, including snow assistance, under the Public Assistance program for any continuous 48... warranted. This assistance excludes regular time costs for the sub-grantees' regular employees. Consistent... Assistance program for any continuous 48-hour period during or proximate to the incident period. All counties...
75 FR 9425 - New Jersey; Major Disaster and Related Determinations
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-02
... protective measures, including snow assistance, under the Public Assistance program for any continuous 48... warranted. This assistance excludes regular time costs for the sub-grantees' regular employees. Consistent... Assistance program for any continuous 48-hour period during or proximate to the incident period. All counties...
ERIC Educational Resources Information Center
Levine, Hermine Zagat
1985-01-01
The author reports company responses to a questionnaire concerning employee assistance programs (EAP). Answers concern EAP structure, staff training, use of outside consultant, services provided by EAPs, program administration, employee confidence in EAPs, advertising the program, program philosophy, problems encountered by EAP users, coverage and…
Tapping into the Forest Management Assistance Programs
John L. Greene; Terry K. Haines
1998-01-01
Use of federal and state forest management assistance programs can enable nonindustial private forest owners to reduce their management expenses and practice better stewardship. This paper summarizes six federal and twelve state assistance programs available to owners in the North Central states. It also describes how to calculate the amount of a government...
ERIC Educational Resources Information Center
Sellers, Debra M.; Markham, Melinda Stafford
2012-01-01
The Fashion an Easier Lifestyle with Assistive Technology (FELAT) curriculum was developed as a needs-based, community educational program provided through a state Cooperative Extension Service. The overall goal for participants was to raise awareness of assistive technology. Program evaluation included a postassessment and subsequent interview to…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-30
... Awards; Office of Native American Programs Training and Technical Assistance; Fiscal Year 2012 AGENCY... (NOFA) for the Office of Native American Programs Training and Technical Assistance (ONAP T&TA). This... nonprofit organizations, as well as for-profit entities to provide Training & Technical Assistance to the...
MEDICAL LABORATORY ASSISTANT, A SUGGESTED GUIDE FOR A TRAINING PROGRAM.
ERIC Educational Resources Information Center
Office of Education (DHEW), Washington, DC.
INFORMATION IS GIVEN TO ASSIST IN ORGANIZING AND ADMINISTERING A TRAINING PROGRAM FOR MEDICAL LABORATORY ASSISTANTS IN A VARIETY OF SETTINGS AND TO PROVIDE GUIDANCE IN ESTABLISHING NEW PROGRAMS AND IN EVALUATING EXISTING ONES. THE MATERIAL WAS PREPARED UNDER THE DIRECTION OF THE NATIONAL COMMITTEE FOR CAREERS IN MEDICAL TECHNOLOGY. PATHOLOGISTS…
34 CFR 280.1 - What is the Magnet Schools Assistance Program?
Code of Federal Regulations, 2011 CFR
2011-07-01
... 34 Education 1 2011-07-01 2011-07-01 false What is the Magnet Schools Assistance Program? 280.1 Section 280.1 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM General § 280.1 What is the...
34 CFR 280.1 - What is the Magnet Schools Assistance Program?
Code of Federal Regulations, 2010 CFR
2010-07-01
... 34 Education 1 2010-07-01 2010-07-01 false What is the Magnet Schools Assistance Program? 280.1 Section 280.1 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM General § 280.1 What is the...
2 CFR 200.202 - Requirement to provide public notice of Federal financial assistance programs.
Code of Federal Regulations, 2014 CFR
2014-01-01
... of Federal financial assistance programs. (a) The Federal awarding agency must notify the public of Federal programs in the Catalog of Federal Domestic Assistance (CFDA), maintained by the General Services... branch of the Federal government. (2) The information that the Federal awarding agency must submit to GSA...
42 CFR 457.810 - Premium assistance programs: Required protections against substitution.
Code of Federal Regulations, 2014 CFR
2014-10-01
..., must provide the protections against substitution of CHIP coverage for coverage under group health... assistance programs must not be greater than the cost of other CHIP coverage for these children; and (2) The... children under premium assistance programs to the cost of other CHIP coverage for these children, done on a...
October 2003 Status of Forces Survey of DoD Civilians: Tabulations of Responses
2004-03-01
182 e. Employee assistance programs .............................................................. 184 f. Support groups...202 60. Mark your level of satisfaction with employee assistance programs ..............204 61. Mark your level of satisfaction...services provided by your organization? e. Employee assistance programs 1. Yes 2. No 3. Not available Percentages Percent Responding 1 2 3 Max
The Power of Peers in Employee Assistance: A Unique Program for a Community College.
ERIC Educational Resources Information Center
Hills, Marcia D.; And Others
1989-01-01
Describes the Red Deer College employee assistance program "Resources for Employee Assistance, Counselling and Health (REACH)" which has moved beyond this traditional approach to become an autonomous program run by employees for employees. Notes REACH is concerned with job performance and coping skills that contribute to individual and…
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-21
... the Biomass Crop Assistance Program AGENCY: Commodity Credit Corporation, USDA. ACTION: Notice of... project areas in Georgia, North Carolina and South Carolina as part of the Biomass Crop Assistance Program... the Biomass Crop Assistance Program (BCAP). BCAP is authorized by Title IX of the Food, Conservation...
15 CFR 700.55 - Assistance programs with Canada and other nations.
Code of Federal Regulations, 2010 CFR
2010-01-01
... the United Kingdom in support of approved programs. (b) Canada. (1) The joint U.S.-Canadian military arrangements for the defense of North America and the integrated nature of their defense industries as set... Assistance programs with Canada and other nations. (a) To promote military assistance to foreign nations...
15 CFR 700.55 - Assistance programs with Canada and other nations.
Code of Federal Regulations, 2013 CFR
2013-01-01
... the United Kingdom in support of approved programs. (b) Canada. (1) The joint U.S.-Canadian military arrangements for the defense of North America and the integrated nature of their defense industries as set... Assistance programs with Canada and other nations. (a) To promote military assistance to foreign nations...
15 CFR 700.55 - Assistance programs with Canada and other nations.
Code of Federal Regulations, 2012 CFR
2012-01-01
... the United Kingdom in support of approved programs. (b) Canada. (1) The joint U.S.-Canadian military arrangements for the defense of North America and the integrated nature of their defense industries as set... Assistance programs with Canada and other nations. (a) To promote military assistance to foreign nations...
15 CFR 700.55 - Assistance programs with Canada and other nations.
Code of Federal Regulations, 2011 CFR
2011-01-01
... the United Kingdom in support of approved programs. (b) Canada. (1) The joint U.S.-Canadian military arrangements for the defense of North America and the integrated nature of their defense industries as set... Assistance programs with Canada and other nations. (a) To promote military assistance to foreign nations...
15 CFR 700.55 - Assistance programs with Canada and other nations.
Code of Federal Regulations, 2014 CFR
2014-01-01
... the United Kingdom in support of approved programs. (b) Canada. (1) The joint U.S.-Canadian military arrangements for the defense of North America and the integrated nature of their defense industries as set... Assistance programs with Canada and other nations. (a) To promote military assistance to foreign nations...
77 FR 60128 - Noncompetitive Supplements to Nursing Assistant and Home Health Aide Program Grantees
Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-02
... Noncompetitive Supplements to Nursing Assistant and Home Health Aide Program Grantees AGENCY: Health Resources... expansion supplements of $100,000 to 10 Nursing Assistant and Home Health Aide (NAHHA) Program grantees to... University Health Sciences Center (TTUHSC) School of Nursing, 302 Pine Street, Abilene, TX 79601, T51HP20702...
Assistance and Enforcement as Strategies for Knowledge Transfer and Program Reform.
ERIC Educational Resources Information Center
Firestone, William A.; Wilson, Bruce L.
Focusing on the promotion of reform and knowledge use in school districts, this paper reports on data from a study investigating assistance and enforcement strategies adopted by three types of regional educational service agencies. Assistance in this context means provision of legal or program knowledge needed to operate successful programs.…
Frank, Deborah A; Neault, Nicole B; Skalicky, Anne; Cook, John T; Wilson, Jacqueline D; Levenson, Suzette; Meyers, Alan F; Heeren, Timothy; Cutts, Diana B; Casey, Patrick H; Black, Maureen M; Berkowitz, Carol
2006-11-01
Public funding for the Low Income Home Energy Assistance Program has never been sufficient to serve more than a small minority of income-eligible households. Low Income Home Energy Assistance Program funding has not increased with recent rapidly rising energy costs, harsh winter conditions, or higher child poverty rates. Although a national performance goal for the Low Income Home Energy Assistance Program is to increase the percentage of recipient households having > or = 1 member < or = 5 years of age, the association of income-eligible households' receipt of the Low Income Home Energy Assistance Program with indicators of well-being in young children has not been evaluated previously. The goal of the current study was to evaluate the association between a family's participation or nonparticipation in the Low Income Home Energy Assistance Program and the anthropometric status and health of their young children. In the ongoing Children's Sentinel Nutrition Assessment Project from June 1998 through December 2004, caregivers with children < 3 years of age in 2 emergency departments and 3 primary care clinics in 5 urban sites participated in cross-sectional surveys regarding household demographics, child's lifetime history of hospitalizations, and, for the past 12 months, household public assistance program participation and household food insecurity, measured by the US Food Security Scale. This scale, in accordance with established procedures, classifies households as food insecure if they report that they cannot afford enough nutritious food for all of the members to lead active, healthy lives. On the day of the interview, children's weight, length, and whether the children were admitted acutely to the hospital from the emergency departments were documented. The study sample consisted only of Low Income Home Energy Assistance Program income-eligible renter households without private insurance who also participated in > or = 1 other means-tested program. In this sample of 7074 caregivers, 16% of families received the Low Income Home Energy Assistance Program, similar to the national rate of 17%. Caregivers who received the Low Income Home Energy Assistance Program were more likely to be single (63% vs 54%), US born (77% vs 68%), and older (mother's mean age: 28.1 vs 26.7 years) but were less likely to be employed (44% vs 47%). Households who received the Low Income Home Energy Assistance Program were more likely to receive Supplemental Nutrition Program for Women, Infants, and Children (85% vs 80%), Supplemental Security Income (13% vs 9%), Temporary Assistance for Needy Families (38% vs 23%), and food stamps (59% vs 37%) and to live in subsidized housing (38% vs 19%) compared with nonrecipients. Children in families participating in the Low Income Home Energy Assistance Program were older than children in nonparticipating families (13.6 vs 12.5 months), were less likely to be uninsured (5% vs 9%), and were more likely to have had a low birth weight < or = 2500 g (17% vs 14%). Families participating in the Low Income Home Energy Assistance Program reported more household food insecurity (24% vs 20%) There were no significant group differences between recipients and nonrecipients in caregiver's education or child's gender. After controlling for these potentially confounding variables, including receipt of other means-tested programs, compared with children in recipient households, those in nonrecipient households had greater adjusted odds of being at aggregate nutritional risk for growth problems, defined as children with weight-for-age below the 5th percentile or weight-for-height below the 10th percentile, with significantly lower mean weight-for-age z scores calculated from age- and gender-specific values from the Centers for Disease Control and Prevention 2000 reference data. However, in adjusted analyses, children aged 2 to 3 years in recipient households were not more likely to be overweight (BMI > 95th percentile) than those in nonrecipient households. Rates of age-adjusted lifetime hospitalization excluding birth and the day of the interview did not differ between Low Income Home Energy Assistance Program recipient groups. Among the 4445 of 7074 children evaluated in the 2 emergency departments, children from eligible households not receiving the Low Income Home Energy Assistance Program had greater adjusted odds than those in recipient households of acute hospital admission on the day of the interview. Even within a low-income renter sample, Low Income Home Energy Assistance Program benefits seem to reach families at the highest social and medical risk with more food insecurity and higher rates of low birth-weight children. Nevertheless, after adjustment for differences in background risk, living in a household receiving the Low Income Home Energy Assistance Program is associated with less anthropometric evidence of undernutrition, no evidence of increased overweight, and lower odds of acute hospitalization from an emergency department visit among young children in low-income renter households compared with children in comparable households not receiving the Low Income Home Energy Assistance Program. The Low Income Home Energy Assistance Program in many states shuts down early each winter when their funding is exhausted. From a clinical perspective, pediatric health providers caring for children from impoverished families should consider encouraging families of these children to apply for the Low Income Home Energy Assistance Program early in the season before funding is depleted. From a public policy perspective, although this cross-sectional study design can only demonstrate associations and not causation, these findings suggest that, particularly as fuel costs and children's poverty rates increase, expanding the Low Income Home Energy Assistance Program funding and meeting the national Low Income Home Energy Assistance Program performance goal of increasing the percentage of recipient households with young children might potentially benefit such children's growth and health.
25 CFR 20.319 - What responsibilities does the general assistance recipient have?
Code of Federal Regulations, 2010 CFR
2010-04-01
..., training and/or other employment assistance programs developed in the ISP; (c) Participate successfully in... SERVICES FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Direct Assistance Employment Requirements § 20... services worker, you, the recipient, must: (a) Participate with the social services worker in developing an...
25 CFR 20.319 - What responsibilities does the general assistance recipient have?
Code of Federal Regulations, 2011 CFR
2011-04-01
..., training and/or other employment assistance programs developed in the ISP; (c) Participate successfully in... SERVICES FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Direct Assistance Employment Requirements § 20... services worker, you, the recipient, must: (a) Participate with the social services worker in developing an...
45 CFR 618.430 - Financial assistance.
Code of Federal Regulations, 2014 CFR
2014-10-01
... NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 618.430 Financial assistance... assistance to any of its students, a recipient shall not: (1) On the basis of sex, provide different amounts...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-07
... DEPARTMENT OF THE TREASURY Internal Revenue Service Community Volunteer Income Tax Assistance... correction to a notice of the Community Volunteer Income Tax Assistance (VITA) Matching Grant Program, which... notice of the availability of application packages for the 2011 Community Volunteer Income Tax Assistance...
The Mobility Assistance Program. A Comprehensive Evaluation Report.
ERIC Educational Resources Information Center
Hicks, Laurabeth H.
The Mobility Assistance Program (MAP) was established to assist U.S. Department of Education employees affected by the reduction in force (RIF). MAP's mission was to provide career transition and outplacement job search assistance to RIF-affected employees. It provided these services: job search, personnel support, training, and professional…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-03
... Directorate; Technical Assistance Request and Evaluation AGENCY: National Protection and Programs Directorate... assistance requests from each State and territory. OEC will use the Technical Assistance Evaluation Form to... electronically. Evaluation forms may be submitted electronically or in paper form. The Office of Management and...
13 CFR 121.301 - What size standards are applicable to financial assistance programs?
Code of Federal Regulations, 2011 CFR
2011-01-01
... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false What size standards are applicable to financial assistance programs? 121.301 Section 121.301 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SMALL BUSINESS SIZE REGULATIONS Size Eligibility Provisions and Standards Size...
13 CFR 121.301 - What size standards are applicable to financial assistance programs?
Code of Federal Regulations, 2010 CFR
2010-01-01
... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false What size standards are applicable to financial assistance programs? 121.301 Section 121.301 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SMALL BUSINESS SIZE REGULATIONS Size Eligibility Provisions and Standards Size...
Nonmetro Businesses Get Federal Credit Assistance, in Some Areas More than Others.
ERIC Educational Resources Information Center
Marlor, Felice S.; McGlone, James M.
1994-01-01
Examines six federal programs offering direct credit assistance to nonfarm businesses in nonmetropolitan areas, 1983-89. The Small Business Loans Program provided 72% of funds. Nonmetropolitan areas overall received federal credit assistance proportional to nonmetro percentage of national population, but assistance was disproportionately low in…
Frequently Asked Questions about the Indian Environmental General Assistance Program (GAP)
Answers to frequently asked questions about the Indian Environmental General Assistance Program (GAP) Guidance on the Award and Management of General Assistance Agreements for Tribes and Intertribal Consortia (Guidance)
40 CFR 35.9000 - Applicability.
Code of Federal Regulations, 2010 CFR
2010-07-01
... ASSISTANCE Financial Assistance for the National Estuary Program § 35.9000 Applicability. This subpart..., organizations, and individuals for pollution abatement and control programs under the National Estuary Program...
40 CFR 35.9000 - Applicability.
Code of Federal Regulations, 2011 CFR
2011-07-01
... ASSISTANCE Financial Assistance for the National Estuary Program § 35.9000 Applicability. This subpart..., organizations, and individuals for pollution abatement and control programs under the National Estuary Program...
40 CFR 35.9000 - Applicability.
Code of Federal Regulations, 2014 CFR
2014-07-01
... ASSISTANCE Financial Assistance for the National Estuary Program § 35.9000 Applicability. This subpart..., organizations, and individuals for pollution abatement and control programs under the National Estuary Program...
40 CFR 35.9000 - Applicability.
Code of Federal Regulations, 2012 CFR
2012-07-01
... ASSISTANCE Financial Assistance for the National Estuary Program § 35.9000 Applicability. This subpart..., organizations, and individuals for pollution abatement and control programs under the National Estuary Program...
40 CFR 35.9000 - Applicability.
Code of Federal Regulations, 2013 CFR
2013-07-01
... ASSISTANCE Financial Assistance for the National Estuary Program § 35.9000 Applicability. This subpart..., organizations, and individuals for pollution abatement and control programs under the National Estuary Program...
24 CFR 886.308 - Maximum total annual contract commitment.
Code of Federal Regulations, 2010 CFR
2010-04-01
... OF HOUSING AND URBAN DEVELOPMENT (SECTION 8 HOUSING ASSISTANCE PROGRAMS, SECTION 202 DIRECT LOAN PROGRAM, SECTION 202 SUPPORTIVE HOUSING FOR THE ELDERLY PROGRAM AND SECTION 811 SUPPORTIVE HOUSING FOR PERSONS WITH DISABILITIES PROGRAM) SECTION 8 HOUSING ASSISTANCE PAYMENTS PROGRAM-SPECIAL ALLOCATIONS...
24 CFR 886.308 - Maximum total annual contract commitment.
Code of Federal Regulations, 2011 CFR
2011-04-01
... OF HOUSING AND URBAN DEVELOPMENT (SECTION 8 HOUSING ASSISTANCE PROGRAMS, SECTION 202 DIRECT LOAN PROGRAM, SECTION 202 SUPPORTIVE HOUSING FOR THE ELDERLY PROGRAM AND SECTION 811 SUPPORTIVE HOUSING FOR PERSONS WITH DISABILITIES PROGRAM) SECTION 8 HOUSING ASSISTANCE PAYMENTS PROGRAM-SPECIAL ALLOCATIONS...
1990-03-06
Deveopmer. Division vkef ore the Subca-rittee c:- Agr~cultural Productirm and Stablllza-t;cn of Prices Senate Ccrratt:ee on Agric -.;ture, \\,utr;.tion and...efficient program, costs [ 1Disaster Assistance: Crop Insurance Can Provide Assistance More Effectively Than Other Programs (GAO/RCED-89-211, Sept. 20...1989). 1ist * should be minimized. On this basis, we identified eight criteria that should be considered in devising an effective disaster assistance
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-08
...In accordance with section 102(a)(4)(C) of the Department of Housing and Urban Development Reform Act of 1989, this announcement notifies the public of funding decisions made by the Department in a competition for funding under the Notice of Funding Availability (NOFA) for the Special Needs Assistance Programs Technical Assistance program. This announcement contains the names of the awardees and amounts of the awards made available by HUD.
ERIC Educational Resources Information Center
Congress of the U.S., Washington, DC. House Committee on Veterans' Affairs.
This report of a hearing on educational benefits for veterans and members of the armed forces focuses on four proposals to establish a new educational assistance program for veterans and members of the armed forces and presents a review of the Veterans Educational Assistance Program (VEAP). Testimony includes statements from members of the U.S.…
Ross, S M; Ross, L E
1995-01-01
Pilots holding the Airline Transport Pilot certificate were surveyed about the seriousness of the alcohol problem in various areas of aviation and about the importance of a number of possible reasons why a pilot might drink and fly. They also rated a number of actions in terms of their potential effectiveness for reducing inappropriate alcohol use, and they evaluated a number of characteristics of employee-assistance programs. Respondents judged employee-assistance programs to be the best way to reduce problem drinking. They also identified areas in which currently available employee-assistance programs could be improved.
Implementing an Employee Assistance Program.
ERIC Educational Resources Information Center
Gam, John; And Others
1983-01-01
Describes in detail the implementation of an employee assistance program in a textile plant. Reviews the historical development, referral process, and termination guidelines of the program and contains descriptive statistics for six periods of the program's operation. (Author/JAC)
A Copay Foundation Assistance Support Program for Patients Receiving Intravenous Cancer Therapy
Rajurkar, Swapnil P.; Presant, Cary A.; Bosserman, Linda D.; McNatt, Wendy J.
2011-01-01
Purpose: With the advent of newer cancer therapies (eg, biologic and cytotoxic), treatment is becoming increasingly expensive for patients with cancer. Patients enrolled in Medicare and commercial insurance plans often have large copay requirements with each treatment cycle. Often, these patients undergo significant financial hardship, and some patients decline treatment. We have developed a support program that works closely with all copay assistance foundations to secure financial assistance to facilitate appropriate treatment. Methods: In September, 2008 we initiated a coordinated program with various copay assistance foundations, including Healthwell, Cancer Care, Patient Access, Chronic Disease Fund, Beckstrand Cancer, Lilly Cares and the Leukemia and Lymphoma Society. Patients requesting assistance with chemotherapy copay were enrolled in this program. Information about income level, chemotherapy regimens, and associated copay was given to these foundations, who then determined the amount of monetary assistance. Results: Since the initiation of this program, of 201 patients who began receiving chemotherapy, 25 (12.4%) requested assistance with this program for either intravenous or oral treatments. The current results of time delays for foundation decision, success rates and administrative costs to secure funding will be presented at the time of the poster presentation. Conclusion: Copay for chemotherapy drugs is a financial hardship for a significant number of patients. Coordinated resources must be provided and reimbursed to facilitate appropriate and sustainable cancer care. This program is a successful model for other centers to adopt. PMID:21731517
12 CFR 1805.102 - Relationship to other Fund programs.
Code of Federal Regulations, 2010 CFR
2010-01-01
... Development Financial Institution from receiving assistance under this part. (b) Liquidity enhancement program. No entity that receives assistance through the liquidity enhancement program authorized under section...
A CBO Paper. How Federal Policies Affect the Allocation of Water
2006-08-01
livestock assistance, disaster reserve assistance, pasture recovery, dairy production assistance, livestock indemnity, tree assistance, and emergency...include ones for emergency conservation and for livestock, dairy , tree, and pasture assistance. 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998...and support programs for the sugar and dairy in- dustries. Those three programs, by increasing the value of water maintained in agriculture through
34 CFR 280.3 - What regulations apply to this program?
Code of Federal Regulations, 2012 CFR
2012-07-01
... SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM General § 280.3 What regulations apply to this program? The following regulations apply to the Magnet Schools Assistance Program... Department of Education programs and activities), 80 (Uniform Administrative Requirements for Grants and...
34 CFR 280.3 - What regulations apply to this program?
Code of Federal Regulations, 2010 CFR
2010-07-01
... SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM General § 280.3 What regulations apply to this program? The following regulations apply to the Magnet Schools Assistance Program... Department of Education programs and activities), 80 (Uniform Administrative Requirements for Grants and...
34 CFR 280.3 - What regulations apply to this program?
Code of Federal Regulations, 2013 CFR
2013-07-01
... SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM General § 280.3 What regulations apply to this program? The following regulations apply to the Magnet Schools Assistance Program... Department of Education programs and activities), 80 (Uniform Administrative Requirements for Grants and...
34 CFR 280.3 - What regulations apply to this program?
Code of Federal Regulations, 2014 CFR
2014-07-01
... SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM General § 280.3 What regulations apply to this program? The following regulations apply to the Magnet Schools Assistance Program... Department of Education programs and activities), 80 (Uniform Administrative Requirements for Grants and...
34 CFR 280.3 - What regulations apply to this program?
Code of Federal Regulations, 2011 CFR
2011-07-01
... SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM General § 280.3 What regulations apply to this program? The following regulations apply to the Magnet Schools Assistance Program... Department of Education programs and activities), 80 (Uniform Administrative Requirements for Grants and...
14 CFR 120.115 - Employee Assistance Program (EAP).
Code of Federal Regulations, 2014 CFR
2014-01-01
... (CONTINUED) AIR CARRIERS AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS DRUG AND ALCOHOL TESTING PROGRAM Drug Testing Program Requirements § 120.115 Employee Assistance Program (EAP). (a... the employee and supervisor EAP training in the employer's drug testing program. [Doc. No. FAA-2008...
Snowden, Lonnie R; McClellan, Sean R
2013-09-01
We investigated the extent to which implementing language assistance programming through contracting with community-based organizations improved the accessibility of mental health care under Medi-Cal (California's Medicaid program) for Spanish-speaking persons with limited English proficiency, and whether it reduced language-based treatment access disparities. Using a time series nonequivalent control group design, we studied county-level penetration of language assistance programming over 10 years (1997-2006) for Spanish-speaking persons with limited English proficiency covered under Medi-Cal. We used linear regression with county fixed effects to control for ongoing trends and other influences. When county mental health plans contracted with community-based organizations, those implementing language assistance programming increased penetration rates of Spanish-language mental health services under Medi-Cal more than other plans (0.28 percentage points, a 25% increase on average; P < .05). However, the increase was insufficient to significantly reduce language-related disparities. Mental health treatment programs operated by community-based organizations may have moderately improved access after implementing required language assistance programming, but the programming did not reduce entrenched disparities in the accessibility of mental health services.
McClellan, Sean R.
2013-01-01
Objectives. We investigated the extent to which implementing language assistance programming through contracting with community-based organizations improved the accessibility of mental health care under Medi-Cal (California’s Medicaid program) for Spanish-speaking persons with limited English proficiency, and whether it reduced language-based treatment access disparities. Methods. Using a time series nonequivalent control group design, we studied county-level penetration of language assistance programming over 10 years (1997–2006) for Spanish-speaking persons with limited English proficiency covered under Medi-Cal. We used linear regression with county fixed effects to control for ongoing trends and other influences. Results. When county mental health plans contracted with community-based organizations, those implementing language assistance programming increased penetration rates of Spanish-language mental health services under Medi-Cal more than other plans (0.28 percentage points, a 25% increase on average; P < .05). However, the increase was insufficient to significantly reduce language-related disparities. Conclusions. Mental health treatment programs operated by community-based organizations may have moderately improved access after implementing required language assistance programming, but the programming did not reduce entrenched disparities in the accessibility of mental health services. PMID:23865663
ERIC Educational Resources Information Center
Blank, Uel; And Others
From 1979 to 1982 an extension education program provided assistance to the tourism industry in rural communities adjoining northeastern Minnesota's Boundary Waters Canoe Area (BWCA). Program activities involved needs assessment, educational and technical assistance to communities and tourism-related firms, marketing programs, grants management…
Code of Federal Regulations, 2010 CFR
2010-04-01
... developed, acquired, or assisted under the IHBG program subject to limitations on cost or design standards... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Is affordable housing developed, acquired, or assisted under the IHBG program subject to limitations on cost or design standards? 1000.156...
Code of Federal Regulations, 2011 CFR
2011-01-01
... § 399.91 Air carrier participation in programs of technical assistance to airlines of less developed... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Air carrier participation in programs of technical assistance to airlines of less developed countries. 399.91 Section 399.91 Aeronautics and Space...
Code of Federal Regulations, 2011 CFR
2011-04-01
... developed, acquired, or assisted under the IHBG program subject to limitations on cost or design standards... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Is affordable housing developed, acquired, or assisted under the IHBG program subject to limitations on cost or design standards? 1000.156...
Code of Federal Regulations, 2010 CFR
2010-04-01
... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Are non-dwelling structures developed, acquired or assisted under the IHBG program subject to limitations on cost or design standards...-dwelling structures developed, acquired or assisted under the IHBG program subject to limitations on cost...
Code of Federal Regulations, 2011 CFR
2011-04-01
... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Are non-dwelling structures developed, acquired or assisted under the IHBG program subject to limitations on cost or design standards...-dwelling structures developed, acquired or assisted under the IHBG program subject to limitations on cost...
Code of Federal Regulations, 2010 CFR
2010-01-01
... § 399.91 Air carrier participation in programs of technical assistance to airlines of less developed... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Air carrier participation in programs of technical assistance to airlines of less developed countries. 399.91 Section 399.91 Aeronautics and Space...
Enlistment Effects and Policy Implications of the Educational Assistance Test Program.
ERIC Educational Resources Information Center
Fernandez, Richard L.
In 1976 Congress terminated the largest federal program of direct student assistance, the GI Bill. This study followed in the wake of growing dissatisfaction with the existing program and of recruiting difficulties experienced by the services during the late 1970s. This report presents the history and results of the Educational Assistance Test…
ERIC Educational Resources Information Center
Seo, You-Jin; Woo, Honguk
2010-01-01
Critical user interface design features of computer-assisted instruction programs in mathematics for students with learning disabilities and corresponding implementation guidelines were identified in this study. Based on the identified features and guidelines, a multimedia computer-assisted instruction program, "Math Explorer", which delivers…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-29
... Loan Program; 84.379 Teacher Education Assistance for College and Higher Education Grant Program; 84... Federal student aid programs authorized under Title IV of the Higher Education Act of 1965, as amended..., William D. Ford Federal Direct Loan (Direct Loan), Teacher Education Assistance for College and Higher...
Brett J. Butler; Marla Markowski-Lindsay; Stephanie Snyder; Paul Catanzaro; David B. Kittredge; Kyle Andrejczyk; Brenton J. Dickinson; Derya Eryilmaz; Jaketon H. Hewes; Paula Randler; Donna Tadle; Michael A. Kilgore
2014-01-01
The USDA Forest Service's Forest Stewardship Program (FSP) is the nation's most prominent private forestry assistance program. We examined the FSP using a multiple analytic approach: analysis of annual FSP accomplishments, survey of state FSP coordinators, analytic comparison of family forest owners receiving and not receiving forestry practice assistance,...
Code of Federal Regulations, 2010 CFR
2010-10-01
... the construction of a rural water supply project under this program? 404.12 Section 404.12 Public... RECLAMATION RURAL WATER SUPPLY PROGRAM Overview § 404.12 Can Reclamation provide assistance with the construction of a rural water supply project under this program? Reclamation may provide assistance with the...
ERIC Educational Resources Information Center
Wilshusen, Gregory C.; Melvin, Valerie C.
2009-01-01
The Veterans Benefits, Health Care, and Information Technology Act of 2006 authorizes the Secretary of Veterans Affairs to establish an educational assistance program for information security. The Information Security Education Assistance Program is envisioned as a means for the Department of Veterans Affairs (VA) to attract and retain individuals…
Code of Federal Regulations, 2012 CFR
2012-04-01
... Section 8 Project-Based Assistance Family Income § 5.615 Public housing program and Section 8 tenant-based... applies to covered families who reside in public housing (part 960 of this title) or receive Section 8... purposes of this section: Covered families. Families who receive welfare assistance or other public...
Code of Federal Regulations, 2013 CFR
2013-04-01
... Section 8 Project-Based Assistance Family Income § 5.615 Public housing program and Section 8 tenant-based... applies to covered families who reside in public housing (part 960 of this title) or receive Section 8... purposes of this section: Covered families. Families who receive welfare assistance or other public...
Code of Federal Regulations, 2011 CFR
2011-04-01
... Section 8 Project-Based Assistance Family Income § 5.615 Public housing program and Section 8 tenant-based... applies to covered families who reside in public housing (part 960 of this title) or receive Section 8... purposes of this section: Covered families. Families who receive welfare assistance or other public...
Code of Federal Regulations, 2010 CFR
2010-04-01
... Section 8 Project-Based Assistance Family Income § 5.615 Public housing program and Section 8 tenant-based... applies to covered families who reside in public housing (part 960 of this title) or receive Section 8... purposes of this section: Covered families. Families who receive welfare assistance or other public...
Code of Federal Regulations, 2014 CFR
2014-04-01
... Section 8 Project-Based Assistance Family Income § 5.615 Public housing program and Section 8 tenant-based... applies to covered families who reside in public housing (part 960 of this title) or receive Section 8... purposes of this section: Covered families. Families who receive welfare assistance or other public...
ERIC Educational Resources Information Center
Mississippi Research and Curriculum Unit for Vocational and Technical Education, State College.
This document, which is intended for use by community and junior colleges throughout Mississippi, contains curriculum frameworks for the course sequences in the physical therapy assistant program. Presented in the introductory section are a description of the program and suggested course sequence. Section I lists baseline competencies, and section…
Code of Federal Regulations, 2010 CFR
2010-01-01
... sources, energy conservation measures for eligible buildings consistent with this part; (b) Will not... 10 Energy 3 2010-01-01 2010-01-01 false Applicant certifications for State grants for technical assistance, program assistance, and marketing. 455.122 Section 455.122 Energy DEPARTMENT OF ENERGY ENERGY...
Code of Federal Regulations, 2010 CFR
2010-04-01
... assistance programs, except for the moderate rehabilitation and the project-based certificate or voucher... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Section 8 project-based assistance... Disabilities: Family Income and Family Payment; Occupancy Requirements for Section 8 Project-Based Assistance...
Code of Federal Regulations, 2011 CFR
2011-04-01
... assistance programs, except for the moderate rehabilitation and the project-based certificate or voucher... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Section 8 project-based assistance... Disabilities: Family Income and Family Payment; Occupancy Requirements for Section 8 Project-Based Assistance...
24 CFR 578.37 - Program components and uses of assistance.
Code of Federal Regulations, 2013 CFR
2013-04-01
...-term (up to 3 months) and/or medium-term (for 3 to 24 months) tenant-based rental assistance, as set... providing short-term and/or medium-term rental assistance to program participants, the rental assistance is... ensuring long-term housing stability. The project is exempt from this requirement if the Violence Against...
24 CFR 578.37 - Program components and uses of assistance.
Code of Federal Regulations, 2014 CFR
2014-04-01
...-term (up to 3 months) and/or medium-term (for 3 to 24 months) tenant-based rental assistance, as set... providing short-term and/or medium-term rental assistance to program participants, the rental assistance is... ensuring long-term housing stability. The project is exempt from this requirement if the Violence Against...
Code of Federal Regulations, 2010 CFR
2010-04-01
... government assistance in cultural exchange programs from coverage of foreign gifts and decorations... assistance provided by a foreign government to facilitate the participation of such employee in a cultural... FOREIGN GOVERNMENTS § 3.12 Exemption of grants and other foreign government assistance in cultural...
Nurse Assistant Instructor Guide.
ERIC Educational Resources Information Center
Connecticut State Dept. of Education, Hartford. Div. of Vocational, Technical, and Adult Education.
This document is designed to assist the teacher in a nurse assistant certification program. The program is intended to prepare students for entry-level employment in a long-term care facility or with a licensed home health care agency. The 135-hour course teaches basic skills in patient care that will qualify the student to assist the licensed…
ERIC Educational Resources Information Center
Florida State Univ., Tallahassee. Center for Instructional Development and Services.
This document demonstrates the relationships among four Florida nursing education programs (home health aide, nursing assistant, patient care assistant, and practical nursing) by listing student performance standards and indicating which ones are required in each program. The 268 student performance standards are arranged in 23 areas of…
A Program to Enhance the Effectiveness of Teaching Assistants.
ERIC Educational Resources Information Center
Cornell Univ., Ithaca, NY. Coll. of Engineering.
This manual is the final report on a two-year project to enhance the effectiveness of teaching assistants. It is designed as a workbook for persons conducting instructional programs for teaching assistants and is specific to teaching assistants in engineering and the natural sciences. The manual contains an introduction and six chapters. Chapter…
ERIC Educational Resources Information Center
Behr, Shirley K.; And Others
The interim report presents an evaluation of TADS (Technical Assistance Development System) through case studies of TADS technical assistance to the staffs of two demonstration programs for preschool handicapped children and their families. Purposes of the study included obtaining indepth descriptions of the technical assistance process to…
ERIC Educational Resources Information Center
San Antonio State Hospital, TX. Office of Education Services.
This instructional manual consists of materials for use in implementing a computer-assisted instructional program in reading skills development for adult nonreaders. Discussed first are the project during which this instructional program and manual were developed and the goals of the computer-assisted beginning reading program, a major feature of…
ERIC Educational Resources Information Center
Office of Economic Opportunity, Washington, DC. Community Action Program.
Published to stimulate local, state, and national groups to develop programs to assist the aged, this catalog presents information about federal grants-in-aid and basic service programs that serve the old, and about foundations and trusts, and national voluntary agencies supporting programs for the aged or willing to assist local groups organizing…
14 CFR 120.115 - Employee Assistance Program (EAP).
Code of Federal Regulations, 2012 CFR
2012-01-01
... (CONTINUED) AIR CARRIERS AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS DRUG AND ALCOHOL TESTING PROGRAM Drug Testing Program Requirements § 120.115 Employee Assistance Program (EAP). (a... employer's drug testing plan submitted to the FAA for approval. ...
14 CFR 120.115 - Employee Assistance Program (EAP).
Code of Federal Regulations, 2011 CFR
2011-01-01
... (CONTINUED) AIR CARRIERS AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS DRUG AND ALCOHOL TESTING PROGRAM Drug Testing Program Requirements § 120.115 Employee Assistance Program (EAP). (a... employer's drug testing plan submitted to the FAA for approval. ...
14 CFR 120.115 - Employee Assistance Program (EAP).
Code of Federal Regulations, 2013 CFR
2013-01-01
... (CONTINUED) AIR CARRIERS AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS DRUG AND ALCOHOL TESTING PROGRAM Drug Testing Program Requirements § 120.115 Employee Assistance Program (EAP). (a... employer's drug testing plan submitted to the FAA for approval. ...
14 CFR 120.115 - Employee Assistance Program (EAP).
Code of Federal Regulations, 2010 CFR
2010-01-01
... (CONTINUED) AIR CARRIERS AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS DRUG AND ALCOHOL TESTING PROGRAM Drug Testing Program Requirements § 120.115 Employee Assistance Program (EAP). (a... employer's drug testing plan submitted to the FAA for approval. ...
Feasibility of Federal assistance for urban mass transportation operating costs
DOT National Transportation Integrated Search
1971-11-01
The contents of the report include the present financial and operating condition of urban mass transportation; the present financial assistance programs for urban mass transportation; an analysis of alternative federal assistance programs; and the se...
Reconceiving SNAP: Is Nutritional Assistance Really Income Support?
ERIC Educational Resources Information Center
Besharov, Douglas J.
2016-01-01
Since its creation, the Supplemental Nutrition Assistance Program (SNAP) has changed from an antihunger program to an income-supplementation program. Because the program (and its predecessor Food Stamp Program) was not designed for this purpose, the result is a program that has many unintended and, many believe, negative effects. The key challenge…
34 CFR 477.4 - What regulations apply?
Code of Federal Regulations, 2011 CFR
2011-07-01
..., DEPARTMENT OF EDUCATION STATE PROGRAM ANALYSIS ASSISTANCE AND POLICY STUDIES PROGRAM General § 477.4 What regulations apply? The following regulations apply to the State Program Analysis Assistance and Policy Studies...
34 CFR 477.4 - What regulations apply?
Code of Federal Regulations, 2010 CFR
2010-07-01
..., DEPARTMENT OF EDUCATION STATE PROGRAM ANALYSIS ASSISTANCE AND POLICY STUDIES PROGRAM General § 477.4 What regulations apply? The following regulations apply to the State Program Analysis Assistance and Policy Studies...
Code of Federal Regulations, 2010 CFR
2010-04-01
... DEVELOPMENT (SECTION 8 HOUSING ASSISTANCE PROGRAMS, SECTION 202 DIRECT LOAN PROGRAM, SECTION 202 SUPPORTIVE...) SECTION 8 HOUSING ASSISTANCE PAYMENTS PROGRAM FOR SUBSTANTIAL REHABILITATION Definitions and Other... insurance programs under the National Housing Act; and (3) Financing by tax-exmpt bonds or other obligations...
Employee assistance program evaluation. Employee perceptions, awareness, and utilization.
Moore, T
1989-12-01
Periodic evaluation is necessary to maintain a quality employee assistance program. This survey was undertaken to determine employee awareness of the existing EAP and their satisfaction with the program. Likewise, the survey allowed for employee input on areas of the program they had concerns with that may have caused hesitancy in further use of the program. The survey not only documents to management that the program is of value to employees and identifies areas where changes may be focused in the future to meet employee needs, but actually serves as a communication tool in itself as a reminder of the availability of the Employee Assistance Program.
Code of Federal Regulations, 2013 CFR
2013-01-01
... AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS DAIRY PRODUCTS 2004 Dairy Disaster Assistance Payment... purposes of administering the 2004 Dairy Disaster Assistance Payment Program established by this subpart. Application means the 2004 Dairy Disaster Assistance Payment Program Application. Application period means the...
Code of Federal Regulations, 2012 CFR
2012-01-01
... AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS DAIRY PRODUCTS 2004 Dairy Disaster Assistance Payment... purposes of administering the 2004 Dairy Disaster Assistance Payment Program established by this subpart. Application means the 2004 Dairy Disaster Assistance Payment Program Application. Application period means the...
Code of Federal Regulations, 2014 CFR
2014-01-01
... AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS DAIRY PRODUCTS 2004 Dairy Disaster Assistance Payment... purposes of administering the 2004 Dairy Disaster Assistance Payment Program established by this subpart. Application means the 2004 Dairy Disaster Assistance Payment Program Application. Application period means the...
Code of Federal Regulations, 2012 CFR
2012-10-01
... DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION GENERAL ADMINISTRATION-GRANT PROGRAMS (PUBLIC ASSISTANCE, MEDICAL ASSISTANCE AND STATE CHILDREN'S HEALTH INSURANCE PROGRAMS) Cost Allocation Plans § 95.505... State agency except expenditures for financial assistance, medical vendor payments, and payments for...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-07
...). SUPPLEMENTARY INFORMATION: The Homeless Emergency Assistance and Rapid Transition to Housing Act of 2009 (HEARTH... Homelessness Grant program. The HEARTH Act also directs HUD to promulgate regulations for these new programs...
24 CFR 92.351 - Affirmative marketing; minority outreach program.
Code of Federal Regulations, 2014 CFR
2014-04-01
... and homebuyer projects containing five or more HOME-assisted housing units. Affirmative marketing...-based rental assistance and downpayment assistance programs. Affirmative marketing steps consist of... disability. If participating jurisdiction's written agreement with the project owner permits the rental...
45 CFR 235.62 - State plan requirements for training programs.
Code of Federal Regulations, 2010 CFR
2010-10-01
... (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES ADMINISTRATION OF FINANCIAL ASSISTANCE PROGRAMS § 235.62 State plan requirements for training programs. A State... 45 Public Welfare 2 2010-10-01 2010-10-01 false State plan requirements for training programs. 235...
DOT National Transportation Integrated Search
2001-01-01
The following progress report is intended to highlight the significant activities of the Florida Transit Training Program and Florida Technical Assistant Program for the 2001 year. Activities of the Florida Statewide Transit Training Program are pres...
An Update: Changes Abound in Forestry Cost-Share Assistance Programs
Robert J. Moulton
1999-01-01
There have been some major changes in the line-up and funding for federal incentive programs that provide technical and financial assistance to non-industrial private forest (NIPF) landowners since I last reported on this subject ("Sorting Through Cost-Share Assistance Programs," Nov./Dec. 1994 Tree Farmer). The purpose of this article is to bring you up to...
1982-01-01
number of countries in the FY 1983 Congressional Presentation Document (CPD) that the United States has security assistance programs with in one form...or another one would find 109 countries listed. Security assistance is a far reaching program and has as its major elements Foreign Military Sales...FMS), International Military Education and Training (IMET), the Military Assistance Program (MAP), commercial sales licensed under the Arms Export
ERIC Educational Resources Information Center
Lenihan, Dawn; McCobb, Emily; Diurba, Amanda; Linder, Deborah; Freeman, Lisa
2016-01-01
Reading assistance dogs can be incorporated into reading programs to increase a child's desire and ability to read. However, more data is needed to demonstrate the effectiveness of such programs. A 5-week reading assistance dog program was implemented to assess feasibility and effectiveness. Participants included 18 children entering the 2nd grade…
ERIC Educational Resources Information Center
Behr, Shirley K.; And Others
The report describes the third and final year of a 3-year case study of the technical assistance process as implemented by the Technical Assistance Development System (TADS) for the staffs of two demonstration programs for preschool handicapped children and their families. Following a review of TADS and the two demonstration programs, the…
ERIC Educational Resources Information Center
Webster, Duane E.
1974-01-01
The Management Review and Analysis Program, an assisted self-study strategy for large academic and research libraries, assists libraries in reviewing and analyzing their current management policies and practices, and provides guidelines for the application of contemporary principles of management for the improvement of library programs. (Author/LS)
Fossil Energy organization restructured
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
The Department of Energy has restructured its fossil energy organization to accommodate increases in activity and visibility of the President's $2.5 billion clean coal technology initiative. The realignment also includes changes in the coal research and development program and in supporting staff functions. In the coal program, changes in the organization include the establishment of two associate deputy assistant secretaries, both reporting to the deputy Assistant Secretary for Coal Technology. One associate deputy assistant secretary will oversee the Clean Coal Technology Program. A second associate deputy assistant secretary will manage the coal research and development program. An organizational chart illustratesmore » the new fossil energy headquarters organization.« less
Elections: DOD Can Strengthen Evaluation of Its Absentee Voting Assistance Program
2010-06-01
Evaluation of Its Absentee Voting Assistance Program June 2010 GAO-10-476 Report Documentation Page Form ApprovedOMB No. 0704-0188 Public...4. TITLE AND SUBTITLE Elections: DOD Can Strengthen Evaluation of Its Absentee Voting Assistance Program 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c...PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES
Doocy, Shannon; Tappis, Hannah; Lyles, Emily; Witiw, Joseph; Aken, Vicki
2017-06-01
The war in Syria has left millions struggling to survive amidst violent conflict, pervasive unemployment, and food insecurity. Although international assistance funding is also at an all-time high, it is insufficient to meet the needs of conflict-affected populations, and there is increasing pressure on humanitarian stakeholders to find more efficient, effective ways to provide assistance. To evaluate 3 different assistance programs (in-kind food commodities, food vouchers, and unrestricted vouchers) in Idleb Governorate of Syria from December 2014 and March 2015. The evaluation used repeated survey data from beneficiary households to determine whether assistance was successful in maintaining food security at the household level. Shopkeeper surveys and program monitoring data were used to assess the impact on markets at the district/governorate levels and compare the cost-efficiency and cost-effectiveness of transfer modalities. Both in-kind food assistance and voucher programs showed positive effects on household food security and economic measures in Idleb; however, no intervention was successful in improving all outcomes measured. Food transfers were more likely to improve food access and food security than vouchers and unrestricted vouchers. Voucher programs were found to be more cost-efficient than in-kind food assistance, and more cost-effective for increasing household food consumption. Continuation of multiple types of transfer programs, including both in-kind assistance and vouchers, will allow humanitarian actors to remain responsive to evolving access and security considerations, local needs, and market dynamics.
34 CFR 648.1 - What is the Graduate Assistance in Areas of National Need program?
Code of Federal Regulations, 2012 CFR
2012-07-01
... 34 Education 3 2012-07-01 2012-07-01 false What is the Graduate Assistance in Areas of National... (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION GRADUATE ASSISTANCE IN AREAS OF NATIONAL NEED General § 648.1 What is the Graduate Assistance in Areas of National Need program? The...
34 CFR 648.1 - What is the Graduate Assistance in Areas of National Need program?
Code of Federal Regulations, 2011 CFR
2011-07-01
... 34 Education 3 2011-07-01 2011-07-01 false What is the Graduate Assistance in Areas of National... (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION GRADUATE ASSISTANCE IN AREAS OF NATIONAL NEED General § 648.1 What is the Graduate Assistance in Areas of National Need program? The...
34 CFR 648.1 - What is the Graduate Assistance in Areas of National Need program?
Code of Federal Regulations, 2014 CFR
2014-07-01
... 34 Education 3 2014-07-01 2014-07-01 false What is the Graduate Assistance in Areas of National... (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION GRADUATE ASSISTANCE IN AREAS OF NATIONAL NEED General § 648.1 What is the Graduate Assistance in Areas of National Need program? The...
34 CFR 648.1 - What is the Graduate Assistance in Areas of National Need program?
Code of Federal Regulations, 2010 CFR
2010-07-01
... 34 Education 3 2010-07-01 2010-07-01 false What is the Graduate Assistance in Areas of National... (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION GRADUATE ASSISTANCE IN AREAS OF NATIONAL NEED General § 648.1 What is the Graduate Assistance in Areas of National Need program? The...
34 CFR 648.1 - What is the Graduate Assistance in Areas of National Need program?
Code of Federal Regulations, 2013 CFR
2013-07-01
... 34 Education 3 2013-07-01 2013-07-01 false What is the Graduate Assistance in Areas of National... (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION GRADUATE ASSISTANCE IN AREAS OF NATIONAL NEED General § 648.1 What is the Graduate Assistance in Areas of National Need program? The...
13 CFR 124.702 - What types of assistance are available through the 7(j) program?
Code of Federal Regulations, 2010 CFR
2010-01-01
..., marketing, and operation of small business concerns; and (b) The identification and development of new... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false What types of assistance are available through the 7(j) program? 124.702 Section 124.702 Business Credit and Assistance SMALL BUSINESS...
Premium assistance in Medicaid and SCHIP: ace in the hole or house of cards?
Shirk, Cynthia; Ryan, Jennifer
2006-07-17
This issue brief explores the use of premium assistance in publicly financed health insurance coverage programs. In the context of Medicaid and the State Children's Health Insurance Program (SCHIP), premium assistance entails using federal and state funds to subsidize the premiums for the purchase of private insurance coverage for eligible individuals. This paper considers the evolution of premium assistance and some of the statutory and administrative limitations, as well as private market factors, that have prevented widespread enrollment in Medicaid or SCHIP premium assistance programs. Finally, this issue brief offers some ideas for potential legislative and/or programmatic changes that could facilitate the use of premium assistance as a mechanism for health coverage expansion.
Index to Computer Assisted Instruction.
ERIC Educational Resources Information Center
Lekan, Helen A., Ed.
The computer assisted instruction (CAI) programs and projects described in this index are listed by subject matter. The index gives the program name, author, source, description, prerequisites, level of instruction, type of student, average completion time, logic and program, purpose for which program was designed, supplementary…
7 CFR 760.500 - Applicability.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 2008 Farm Bill). (b) Eligible orchardists and nursery tree growers will be compensated as specified in... SPECIAL PROGRAMS INDEMNITY PAYMENT PROGRAMS Tree Assistance Program § 760.500 Applicability. (a) This subpart establishes the terms and conditions under which the Tree Assistance Program (TAP) will be...
7 CFR 760.500 - Applicability.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 2008 Farm Bill). (b) Eligible orchardists and nursery tree growers will be compensated as specified in... SPECIAL PROGRAMS INDEMNITY PAYMENT PROGRAMS Tree Assistance Program § 760.500 Applicability. (a) This subpart establishes the terms and conditions under which the Tree Assistance Program (TAP) will be...
7 CFR 760.500 - Applicability.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 2008 Farm Bill). (b) Eligible orchardists and nursery tree growers will be compensated as specified in... SPECIAL PROGRAMS INDEMNITY PAYMENT PROGRAMS Tree Assistance Program § 760.500 Applicability. (a) This subpart establishes the terms and conditions under which the Tree Assistance Program (TAP) will be...
7 CFR 760.500 - Applicability.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 2008 Farm Bill). (b) Eligible orchardists and nursery tree growers will be compensated as specified in... SPECIAL PROGRAMS INDEMNITY PAYMENT PROGRAMS Tree Assistance Program § 760.500 Applicability. (a) This subpart establishes the terms and conditions under which the Tree Assistance Program (TAP) will be...
Code of Federal Regulations, 2010 CFR
2010-07-01
... Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR SMALL OPERATOR ASSISTANCE PERMANENT REGULATORY PROGRAM-SMALL OPERATOR ASSISTANCE PROGRAM § 795.3 Definitions. As used in... who has the authority and responsibility for overall management of the Small Operator Assistance...
45 CFR 95.611 - Prior approval conditions.
Code of Federal Regulations, 2014 CFR
2014-10-01
...-GRANT PROGRAMS (PUBLIC ASSISTANCE, MEDICAL ASSISTANCE AND STATE CHILDREN'S HEALTH INSURANCE PROGRAMS... requests for approval which affect only one approving component of HHS (CMS, OCSE, or Children's Bureau... days for major milestones. For Aid to Families with Dependent Children (AFDC) Family Assistance...
45 CFR 95.611 - Prior approval conditions.
Code of Federal Regulations, 2012 CFR
2012-10-01
...-GRANT PROGRAMS (PUBLIC ASSISTANCE, MEDICAL ASSISTANCE AND STATE CHILDREN'S HEALTH INSURANCE PROGRAMS... requests for approval which affect only one approving component of HHS (CMS, OCSE, or Children's Bureau... days for major milestones. For Aid to Families with Dependent Children (AFDC) Family Assistance...
45 CFR 95.611 - Prior approval conditions.
Code of Federal Regulations, 2013 CFR
2013-10-01
...-GRANT PROGRAMS (PUBLIC ASSISTANCE, MEDICAL ASSISTANCE AND STATE CHILDREN'S HEALTH INSURANCE PROGRAMS... requests for approval which affect only one approving component of HHS (CMS, OCSE, or Children's Bureau... days for major milestones. For Aid to Families with Dependent Children (AFDC) Family Assistance...
45 CFR 95.611 - Prior approval conditions.
Code of Federal Regulations, 2011 CFR
2011-10-01
...-GRANT PROGRAMS (PUBLIC ASSISTANCE, MEDICAL ASSISTANCE AND STATE CHILDREN'S HEALTH INSURANCE PROGRAMS... requests for approval which affect only one approving component of HHS (CMS, OCSE, or Children's Bureau... days for major milestones. For Aid to Families with Dependent Children (AFDC) Family Assistance...
7 CFR 3570.88 - Management assistance.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 7 Agriculture 15 2012-01-01 2012-01-01 false Management assistance. 3570.88 Section 3570.88 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE COMMUNITY PROGRAMS Community Facilities Grant Program § 3570.88 Management assistance. Grant...
7 CFR 3570.88 - Management assistance.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 7 Agriculture 15 2011-01-01 2011-01-01 false Management assistance. 3570.88 Section 3570.88 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE COMMUNITY PROGRAMS Community Facilities Grant Program § 3570.88 Management assistance. Grant...
7 CFR 3570.88 - Management assistance.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 7 Agriculture 15 2014-01-01 2014-01-01 false Management assistance. 3570.88 Section 3570.88 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE COMMUNITY PROGRAMS Community Facilities Grant Program § 3570.88 Management assistance. Grant...
34 CFR 668.230 - Scope and purpose.
Code of Federal Regulations, 2010 CFR
2010-07-01
..., DEPARTMENT OF EDUCATION STUDENT ASSISTANCE GENERAL PROVISIONS Financial Assistance for Students With... disabilities. Students enrolled in these programs are eligible for Federal financial assistance under the Federal Pell Grant, FSEOG, and FWS programs. Except for provisions related to needs analysis, the...
34 CFR 668.230 - Scope and purpose.
Code of Federal Regulations, 2011 CFR
2011-07-01
..., DEPARTMENT OF EDUCATION STUDENT ASSISTANCE GENERAL PROVISIONS Financial Assistance for Students With... disabilities. Students enrolled in these programs are eligible for Federal financial assistance under the Federal Pell Grant, FSEOG, and FWS programs. Except for provisions related to needs analysis, the...
7 CFR 3570.88 - Management assistance.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 15 2010-01-01 2010-01-01 false Management assistance. 3570.88 Section 3570.88 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE COMMUNITY PROGRAMS Community Facilities Grant Program § 3570.88 Management assistance. Grant...
Land Acquisition and Relocation Assistance for Airport Improvement Program (AIP) Assisted Projects
DOT National Transportation Integrated Search
2017-07-10
This advisory circular (AC) provides guidance to sponsors of airport projects developed under the Airport Improvement Program (AIP) to meet the requirements of the Uniform Relocation Assistance and Real Property Acquisition Policies Act of 1970 (Pl 9...
Evaluation of freeway motorist assist : staff summary, February 2010.
DOT National Transportation Integrated Search
2010-02-01
This research document builds on the previous Return on Investment (ROI) Study of Motorist Assist (1994) that evaluated the St. Louis Motor Assist program to establish and update current benefits of this program. The following is a summary of finding...
44 CFR 16.150 - Program accessibility: Existing facilities.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Program accessibility: Existing facilities. 16.150 Section 16.150 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT... IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE FEDERAL EMERGENCY MANAGEMENT AGENCY § 16.150 Program...