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Sample records for astatine 218

  1. Atomic Mass and Nuclear Binding Energy for At-218 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-218 (Astatine, atomic number Z = 85, mass number A = 218).

  2. Radiochemistry of astatine

    SciTech Connect

    Ruth, T.J.; Dombsky, M.; D'Auria, J.M.; Ward, T.E.

    1988-01-01

    This monograph is a review of the literature through 1987 and covers the methods of producing the radioisotopes of astatine and the inorganic, nuclear, and organic chemistry of astatine. The discussion is limited to chemical and physical chemical properties of astatine. The monograph, after the introduction, is divided into chapters titled: production methods, nuclear spectroscopy, chemistry of astatine, separation and isolation (dry and wet), and selected procedures. 209 refs., 15 figs., 7 tabs. (DLC)

  3. Electrophilic addition of astatine

    SciTech Connect

    Norseev, Yu.V.; Vasaros, L.; Nhan, D.D.; Huan, N.K.

    1988-03-01

    It has been shown for the first time that astatine is capable of undergoing addition reactions to unsaturated hydrocarbons. A new compound of astatine, viz., ethylene astatohydrin, has been obtained, and its retention numbers of squalane, Apiezon, and tricresyl phosphate have been found. The influence of various factors on the formation of ethylene astatohydrin has been studied. It has been concluded on the basis of the results obtained that the univalent cations of astatine in an acidic medium is protonated hypoastatous acid.

  4. Preparation of astatine-labeled monoclonal antibodies

    SciTech Connect

    Milesz, S.; Norseev, Yu.V.; Szucs, Z. |

    1995-07-01

    In the cationic state astatine forms a stable complex with diethylenetriaminepentaacetic acid. Thanks to this complex, astatine can be bound to monoclonal antibodies of the RYa{sub 1} type. The most favorable conditions for preparing astatine-labeled antibodies are established. The chromatographic analysis and electromigration experiments showed that astatine is firmly linked to a biomolecule in vitro and it did not escape from labeled monoclonal antibodies even under treatment with such highly effective astatine-complexing agent as thiourea. The immune activity of astatine-labeled antibodies did not change even after 20 h.

  5. Condensed Astatine: Monatomic and Metallic

    NASA Astrophysics Data System (ADS)

    Hermann, Andreas; Hoffmann, Roald; Ashcroft, N. W.

    2013-09-01

    The condensed matter properties of the nominal terminating element of the halogen group with atomic number 85, astatine, are as yet unknown. In the intervening more than 70 years since its discovery significant advances have been made in substrate cooling and the other techniques necessary for the production of the element to the point where we might now enquire about the key properties astatine might have if it attained a condensed phase. This subject is addressed here using density functional theory and structural selection methods, with an accounting for relativistic physics that is essential. Condensed astatine is predicted to be quite different in fascinating ways from iodine, being already at 1 atm a metal, and monatomic at that, and possibly a superconductor (as is dense iodine).

  6. Condensed astatine: monatomic and metallic.

    PubMed

    Hermann, Andreas; Hoffmann, Roald; Ashcroft, N W

    2013-09-13

    The condensed matter properties of the nominal terminating element of the halogen group with atomic number 85, astatine, are as yet unknown. In the intervening more than 70 years since its discovery significant advances have been made in substrate cooling and the other techniques necessary for the production of the element to the point where we might now enquire about the key properties astatine might have if it attained a condensed phase. This subject is addressed here using density functional theory and structural selection methods, with an accounting for relativistic physics that is essential. Condensed astatine is predicted to be quite different in fascinating ways from iodine, being already at 1 atm a metal, and monatomic at that, and possibly a superconductor (as is dense iodine).

  7. Astatine Radiopharmaceuticals: Prospects and Problems

    PubMed Central

    Vaidyanathan, Ganesan; Zalutsky, Michael R.

    2010-01-01

    For the treatment of minimum residual diseases such micrometastases and residual tumor margins that remain after debulking of the primary tumor, targeted radiotherapy using radiopharmaceuticals tagged with α-particle-emitting radionuclides is very attractive. In addition to the their short range in tissue, which helps minimize harmful effects on adjacent normal tissues, α-particles, being high LET radiation, have several radiobiological advantages. The heavy halogen, astatine-211 is one of the prominent α-particle-emitting radionuclides in practice. Being a halogen, it can often be incorporated into biomolecules of interest by adapting radioiodination chemistry. A wide spectrum of compounds from the simple [211At]astatide ion to small organic molecules, peptides, and large proteins labeled with 211At have been investigated with at least two reaching the stage of clinical evaluation. The chemistry, cytotoxic advantages, biodistribution studies, and microdosimetry/pharmacokinetic modeling of some of these agents will be reviewed. In addition, potential problems such as the harmful effect of radiolysis on the synthesis, lack of sufficient in vivo stability of astatinated compounds, and possible adverse effects when they are systemically administered will be discussed. PMID:20150978

  8. Astatine Radiopharmaceuticals: Prospects and Problems.

    PubMed

    Vaidyanathan, Ganesan; Zalutsky, Michael R

    2008-09-01

    For the treatment of minimum residual diseases such micrometastases and residual tumor margins that remain after debulking of the primary tumor, targeted radiotherapy using radiopharmaceuticals tagged with alpha-particle-emitting radionuclides is very attractive. In addition to the their short range in tissue, which helps minimize harmful effects on adjacent normal tissues, alpha-particles, being high LET radiation, have several radiobiological advantages. The heavy halogen, astatine-211 is one of the prominent alpha-particle-emitting radionuclides in practice. Being a halogen, it can often be incorporated into biomolecules of interest by adapting radioiodination chemistry. A wide spectrum of compounds from the simple [(211)At]astatide ion to small organic molecules, peptides, and large proteins labeled with (211)At have been investigated with at least two reaching the stage of clinical evaluation. The chemistry, cytotoxic advantages, biodistribution studies, and microdosimetry/pharmacokinetic modeling of some of these agents will be reviewed. In addition, potential problems such as the harmful effect of radiolysis on the synthesis, lack of sufficient in vivo stability of astatinated compounds, and possible adverse effects when they are systemically administered will be discussed.

  9. Astatine and Yttrium Resonant Ionization Laser Spectroscopy

    NASA Astrophysics Data System (ADS)

    Teigelhoefer, Andrea

    Providing intense, contamination-free beams of rare isotopes to experiments is a challenging task. At isotope separator on-line facilities such as ISAC at TRIUMF, the choice of production target and ion source are key to the successful beam delivery. Due to their element-selectivity, high efficiency and versatility, resonant ionization laser ion sources (RILIS) gain increasingly in importance. The spectroscopic data available are typically incomplete in the region of excited- and autoionizing atomic states. In order to find the most efficient ionization scheme for a particular element, further spectroscopy is often required. The development of efficient laser resonant ionization schemes for yttrium and astatine is presented in this thesis. For yttrium, two ionization schemes with comparable relative intensities were found. Since for astatine, only two transitions were known, the focus was to provide data on atomic energy levels using resonance ionization spectroscopy. Altogether 41 previously unknown astatine energy levels were found.

  10. Astatine-211: production and availability.

    PubMed

    Zalutsky, Michael R; Pruszynski, Marek

    2011-07-01

    The 7.2-h half life radiohalogen (211)At offers many potential advantages for targeted α-particle therapy; however, its use for this purpose is constrained by its limited availability. Astatine-211 can be produced in reasonable yield from natural bismuth targets via the (209)Bi(α,2n)(211)At nuclear reaction utilizing straightforward methods. There is some debate as to the best incident α-particle energy for maximizing 211At production while minimizing production of (210)At, which is problematic because of its 138.4-day half life α-particle emitting daughter, (210)Po. The intrinsic cost for producing (211)At is reasonably modest and comparable to that of commercially available (123)I. The major impediment to (211)At availability is attributed to the need for a medium energy α-particle beam for its production. On the other hand, there are about 30 cyclotrons in the world that have the beam characteristics required for (211)At production.

  11. Establishment of an European Astatine Collaboration

    SciTech Connect

    Weinreich, R. |

    1994-12-31

    {sup 211}At is an extremely radiotoxic nuclide. It decays with a half-life of 7.2 hrs by emission of (on average) one {alpha}-particle and a number of Auger and Coster-Kronig electrons per decay. The maximum range of the a-particles is 80 {mu}m, consequently a few cell diameters. In the last years, the general interest in astatine labelled compounds for radionuclide therapy has been reinforced: studies of the radiobiological behaviour of {sup 211}At in cell culture-experiments confirmed clearly its usefulness for radiotherapeutic applications. Astatine compounds have been found which are relatively stable and useful as linkers between the nuclide and carrier proteins. A clinical study using {sup 211}At-Methylene blue as radiotoxic substance as well as tumour-seeking ligand is now under consideration. On the other hand, the low availability of the nuclide is still the most important limitation for a broader clinical application: for production of this nuclide, {alpha}-particles of 28 MeV are needed. These particles are mostly generated in medium-energy multi-particle accelerators of variable energy. Such accelerators, however, are generally used by different research groups with different research aims and consequently different beamtime modes.

  12. Production and separation of Astatine Radionuclides: some new addition to Astatine Chemistry.

    PubMed

    Roy, Kamalika; Lahiri, Susanta

    2008-05-01

    For the first time no-carrier-added (nca) (209,210)At radionuclides were produced by heavy ion ((7)Li) activation from 4 mg/cm(2) lead nitrate target. Astatine was separated from the bulk target by three different approaches. Nca astatine radionuclide was selectively partitioned in the (i) polymer rich phase of an aqueous biphasic system consisting of polyethylene glycol (PEG) 4000 (50% w/w) and 2M Na(2)SO(4) solution (ii) aqueous phase of a liquid liquid extraction system being comprised of a liquid cation exchanger, HDEHP (di-2-ethylhexyl phosphoric acid) (0.5%) and liquor ammonia (iii) liquid phase of a solid liquid extraction system of cation exchange resin Dowex-50 and 10(-6)M HCl. Very high separation factors have been achieved in all the three methods.

  13. Discovery of the astatine, radon, francium, and radium isotopes

    NASA Astrophysics Data System (ADS)

    Fry, C.; Thoennessen, M.

    2013-09-01

    Thirty-nine astatine, thirty-nine radon, thirty-five francium, and thirty-four radium isotopes have so far been observed; the discovery of these isotopes is described. For each isotope a brief summary of the first refereed publication, including the production and identification method, is presented.

  14. Process for producing astatine-211 for radiopharmaceutical use

    DOEpatents

    Mirzadeh, Saed; Lambrecht, Richard M.

    1987-01-01

    A process for reliably and consistently producing astatine-211 in small controlled volumes of a solution, which is selected from a choice of solvents that are useful in selected radiopharmaceutical procedures in which the At-211 activities are to be applied.

  15. Discovery of the astatine, radon, francium, and radium isotopes

    SciTech Connect

    Fry, C.; Thoennessen, M.

    2013-09-15

    Thirty-nine astatine, thirty-nine radon, thirty-five francium, and thirty-four radium isotopes have so far been observed; the discovery of these isotopes is described. For each isotope a brief summary of the first refereed publication, including the production and identification method, is presented.

  16. Process for producing astatine-211 for radiopharmaceutical use

    DOEpatents

    Mirzadeh, S.; Lambrecht, R.M.

    1984-04-10

    A process is described for reliably and consistently producing astatine-211 in small controlled volumes of a solution, which is selected from a choice of solvents that are useful in selected radiopharmaceutical procedures in which the At-211 activities are to be applied. 4 figures, 1 table.

  17. Incorporation of thiosemicarbazide in Amberlite IRC-50 for separation of astatine from alpha-irradiated bismuth oxide.

    PubMed

    Roy, Kamalika; Basu, S; Ramaswami, A; Nayak, Dalia; Lahiri, Susanta

    2004-06-01

    A chelating resin was synthesized by incorporating thiosemicarbazide into Amberlite IRC-50, a weakly acidic polymer. Astatine radionuclides produced by alpha-irradiating bismuth oxide were separated using the newly synthesized chelating resin. The resin showed high selectivity for astatine. The adsorbed astatine was recovered using 0.1M EDTA at pH approximately 10.

  18. Delayed and In-beam Spectroscopy on Francium and Astatine Nuclei at the Proton Drip Line

    NASA Astrophysics Data System (ADS)

    Uusitalo, J.; Jakobsson, U.

    2011-11-01

    Delayed and in-beam spectroscopy on francium and astatine nuclei at and beyond the proton drip line has been performed. In neutron deficient astatine nuclei a shift to deformed shapes as a function of decreasing neutron has been obtained. In neutron deficient francium isotope the same shift is evident.

  19. Delayed and In-beam Spectroscopy on Francium and Astatine Nuclei at the Proton Drip Line

    SciTech Connect

    Uusitalo, J.; Jakobsson, U.; Collaboration: RITU-Gamma Gollaboration

    2011-11-30

    Delayed and in-beam spectroscopy on francium and astatine nuclei at and beyond the proton drip line has been performed. In neutron deficient astatine nuclei a shift to deformed shapes as a function of decreasing neutron has been obtained. In neutron deficient francium isotope the same shift is evident.

  20. Graphs for Isotopes of 85-At(Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides a graphic representation of nucleon separation energies and residual interaction parameters for isotopes of the chemical element 85-At (Astatine, atomic number Z = 85).

  1. Measurement of the first ionization potential of astatine by laser ionization spectroscopy

    NASA Astrophysics Data System (ADS)

    Rothe, S.; Andreyev, A. N.; Antalic, S.; Borschevsky, A.; Capponi, L.; Cocolios, T. E.; de Witte, H.; Eliav, E.; Fedorov, D. V.; Fedosseev, V. N.; Fink, D. A.; Fritzsche, S.; Ghys, L.; Huyse, M.; Imai, N.; Kaldor, U.; Kudryavtsev, Yuri; Köster, U.; Lane, J. F. W.; Lassen, J.; Liberati, V.; Lynch, K. M.; Marsh, B. A.; Nishio, K.; Pauwels, D.; Pershina, V.; Popescu, L.; Procter, T. J.; Radulov, D.; Raeder, S.; Rajabali, M. M.; Rapisarda, E.; Rossel, R. E.; Sandhu, K.; Seliverstov, M. D.; Sjödin, A. M.; van den Bergh, P.; van Duppen, P.; Venhart, M.; Wakabayashi, Y.; Wendt, K. D. A.

    2013-05-01

    The radioactive element astatine exists only in trace amounts in nature. Its properties can therefore only be explored by study of the minute quantities of artificially produced isotopes or by performing theoretical calculations. One of the most important properties influencing the chemical behaviour is the energy required to remove one electron from the valence shell, referred to as the ionization potential. Here we use laser spectroscopy to probe the optical spectrum of astatine near the ionization threshold. The observed series of Rydberg states enabled the first determination of the ionization potential of the astatine atom, 9.31751(8) eV. New ab initio calculations are performed to support the experimental result. The measured value serves as a benchmark for quantum chemistry calculations of the properties of astatine as well as for the theoretical prediction of the ionization potential of superheavy element 117, the heaviest homologue of astatine.

  2. Measurement of the first ionization potential of astatine by laser ionization spectroscopy

    PubMed Central

    Rothe, S.; Andreyev, A. N.; Antalic, S.; Borschevsky, A.; Capponi, L.; Cocolios, T. E.; De Witte, H.; Eliav, E.; Fedorov, D. V.; Fedosseev, V. N.; Fink, D. A.; Fritzsche, S.; Ghys, L.; Huyse, M.; Imai, N.; Kaldor, U.; Kudryavtsev, Yuri; Köster, U.; Lane, J. F. W.; Lassen, J.; Liberati, V.; Lynch, K. M.; Marsh, B. A.; Nishio, K.; Pauwels, D.; Pershina, V.; Popescu, L.; Procter, T. J.; Radulov, D.; Raeder, S.; Rajabali, M. M.; Rapisarda, E.; Rossel, R. E.; Sandhu, K.; Seliverstov, M. D.; Sjödin, A. M.; Van den Bergh, P.; Van Duppen, P.; Venhart, M.; Wakabayashi, Y.; Wendt, K. D. A.

    2013-01-01

    The radioactive element astatine exists only in trace amounts in nature. Its properties can therefore only be explored by study of the minute quantities of artificially produced isotopes or by performing theoretical calculations. One of the most important properties influencing the chemical behaviour is the energy required to remove one electron from the valence shell, referred to as the ionization potential. Here we use laser spectroscopy to probe the optical spectrum of astatine near the ionization threshold. The observed series of Rydberg states enabled the first determination of the ionization potential of the astatine atom, 9.31751(8) eV. New ab initio calculations are performed to support the experimental result. The measured value serves as a benchmark for quantum chemistry calculations of the properties of astatine as well as for the theoretical prediction of the ionization potential of superheavy element 117, the heaviest homologue of astatine. PMID:23673620

  3. Measurement of the first ionization potential of astatine by laser ionization spectroscopy.

    PubMed

    Rothe, S; Andreyev, A N; Antalic, S; Borschevsky, A; Capponi, L; Cocolios, T E; De Witte, H; Eliav, E; Fedorov, D V; Fedosseev, V N; Fink, D A; Fritzsche, S; Ghys, L; Huyse, M; Imai, N; Kaldor, U; Kudryavtsev, Yuri; Köster, U; Lane, J F W; Lassen, J; Liberati, V; Lynch, K M; Marsh, B A; Nishio, K; Pauwels, D; Pershina, V; Popescu, L; Procter, T J; Radulov, D; Raeder, S; Rajabali, M M; Rapisarda, E; Rossel, R E; Sandhu, K; Seliverstov, M D; Sjödin, A M; Van den Bergh, P; Van Duppen, P; Venhart, M; Wakabayashi, Y; Wendt, K D A

    2013-01-01

    The radioactive element astatine exists only in trace amounts in nature. Its properties can therefore only be explored by study of the minute quantities of artificially produced isotopes or by performing theoretical calculations. One of the most important properties influencing the chemical behaviour is the energy required to remove one electron from the valence shell, referred to as the ionization potential. Here we use laser spectroscopy to probe the optical spectrum of astatine near the ionization threshold. The observed series of Rydberg states enabled the first determination of the ionization potential of the astatine atom, 9.31751(8) eV. New ab initio calculations are performed to support the experimental result. The measured value serves as a benchmark for quantum chemistry calculations of the properties of astatine as well as for the theoretical prediction of the ionization potential of superheavy element 117, the heaviest homologue of astatine.

  4. Scrutinizing "Invisible" astatine: A challenge for modern density functionals.

    PubMed

    Sergentu, Dumitru-Claudiu; David, Grégoire; Montavon, Gilles; Maurice, Rémi; Galland, Nicolas

    2016-06-05

    The main-group 6p elements did not receive much attention in the development of recent density functionals. In many cases it is still difficult to choose among the modern ones a relevant functional for various applications. Here, we illustrate the case of astatine species (At, Z = 85) and we report the first, and quite complete, benchmark study on several properties concerning such species. Insights on geometries, transition energies and thermodynamic properties of a set of 19 astatine species, for which reference experimental or theoretical data has been reported, are obtained with relativistic (two-component) density functional theory calculations. An extensive set of widely used functionals is employed. The hybrid meta-generalized gradient approximation (meta-GGA) PW6B95 functional is overall the best choice. It is worth noting that the range-separated HSE06 functional as well as the old and very popular B3LYP and PBE0 hybrid-GGAs appear to perform quite well too. Moreover, we found that astatine chemistry in solution can accurately be predicted using implicit solvent models, provided that specific parameters are used to build At cavities. © 2016 Wiley Periodicals, Inc.

  5. Synthesis and Evaluation of Astatinated N-[2-(Maleimido)ethyl]-3-(trimethylstannyl)benzamide Immunoconjugates.

    PubMed

    Aneheim, Emma; Gustafsson, Anna; Albertsson, Per; Bäck, Tom; Jensen, Holger; Palm, Stig; Svedhem, Sofia; Lindegren, Sture

    2016-03-16

    Effective treatment of metastasis is a great challenge in the treatment of different types of cancers. Targeted alpha therapy utilizes the short tissue range (50-100 μm) of α particles, making the method suitable for treatment of disseminated occult cancers in the form of microtumors or even single cancer cells. A promising radioactive nuclide for this type of therapy is astatine-211. Astatine-211 attached to tumor-specific antibodies as carrier molecules is a system currently under investigation for use in targeted alpha therapy. In the common radiolabeling procedure, astatine is coupled to the antibody arbitrarily on lysine residues. By instead coupling astatine to disulfide bridges in the antibody structure, the immunoreactivity of the antibody conjugates could possibly be increased. Here, the disulfide-based conjugation was performed using a new coupling reagent, maleimidoethyl 3-(trimethylstannyl)benzamide (MSB), and evaluated for chemical stability in vitro. The immunoconjugates were subsequently astatinated, resulting in both high radiochemical yield and high specific activity. The MSB-conjugate was shown to be stable with a long shelf life prior to the astatination. In a comparison of the in vivo distribution of the new immunoconjugate with other tin-based immunoconjugates in tumor-bearing mice, the MSB conjugation method was found to be a viable option for successful astatine labeling of different monoclonal antibodies.

  6. Atomic Mass and Nuclear Binding Energy for At-223 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-223 (Astatine, atomic number Z = 85, mass number A = 223).

  7. Atomic Mass and Nuclear Binding Energy for At-245 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-245 (Astatine, atomic number Z = 85, mass number A = 245).

  8. Atomic Mass and Nuclear Binding Energy for At-270 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-270 (Astatine, atomic number Z = 85, mass number A = 270).

  9. Atomic Mass and Nuclear Binding Energy for At-258 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-258 (Astatine, atomic number Z = 85, mass number A = 258).

  10. Atomic Mass and Nuclear Binding Energy for At-271 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-271 (Astatine, atomic number Z = 85, mass number A = 271).

  11. Atomic Mass and Nuclear Binding Energy for At-261 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-261 (Astatine, atomic number Z = 85, mass number A = 261).

  12. Atomic Mass and Nuclear Binding Energy for At-254 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-254 (Astatine, atomic number Z = 85, mass number A = 254).

  13. Atomic Mass and Nuclear Binding Energy for At-238 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-238 (Astatine, atomic number Z = 85, mass number A = 238).

  14. Atomic Mass and Nuclear Binding Energy for At-281 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-281 (Astatine, atomic number Z = 85, mass number A = 281).

  15. Atomic Mass and Nuclear Binding Energy for At-228 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-228 (Astatine, atomic number Z = 85, mass number A = 228).

  16. Atomic Mass and Nuclear Binding Energy for At-248 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-248 (Astatine, atomic number Z = 85, mass number A = 248).

  17. Atomic Mass and Nuclear Binding Energy for At-282 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-282 (Astatine, atomic number Z = 85, mass number A = 282).

  18. Atomic Mass and Nuclear Binding Energy for At-278 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-278 (Astatine, atomic number Z = 85, mass number A = 278).

  19. Atomic Mass and Nuclear Binding Energy for At-230 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-230 (Astatine, atomic number Z = 85, mass number A = 230).

  20. Atomic Mass and Nuclear Binding Energy for At-284 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-284 (Astatine, atomic number Z = 85, mass number A = 284).

  1. Atomic Mass and Nuclear Binding Energy for At-280 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-280 (Astatine, atomic number Z = 85, mass number A = 280).

  2. Atomic Mass and Nuclear Binding Energy for At-227 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-227 (Astatine, atomic number Z = 85, mass number A = 227).

  3. Atomic Mass and Nuclear Binding Energy for At-283 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-283 (Astatine, atomic number Z = 85, mass number A = 283).

  4. Atomic Mass and Nuclear Binding Energy for At-273 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-273 (Astatine, atomic number Z = 85, mass number A = 273).

  5. Astatine-211-tellurium radiocolloid cures experimental malignant ascites

    SciTech Connect

    Bloomer, W.D.; McLaughlin, W.H.; Neirinckx, R.D.; Adelstein, S.J.; Gordon, P.R.; Ruth, T.J.; Wolf, A.P.

    1981-04-17

    An investigation of the efficacy of astatine-211-tellurium colloid for the treatment of experimental malignant ascites in mice reveals that this ..cap alpha..-emitting radiocolloid can be curative without causing undue toxicity to normal tissue. By comparison, negatron-emitting phosphorus-32 as colloidal chromic phosphate had no antineoplastic activity. The most compelling explanation for this striking difference is the dense ionization and short range of action associated with ..cap alpha..-emission. These results have important implications for the development and use of ..cap alpha..-emitters as radiocolloid therapy for the treatment of human tumors.

  6. Atomic Mass and Nuclear Binding Energy for At-222 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-222 (Astatine, atomic number Z = 85, mass number A = 222).

  7. Atomic Mass and Nuclear Binding Energy for At-275 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-275 (Astatine, atomic number Z = 85, mass number A = 275).

  8. Atomic Mass and Nuclear Binding Energy for At-224 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-224 (Astatine, atomic number Z = 85, mass number A = 224).

  9. Atomic Mass and Nuclear Binding Energy for At-252 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-252 (Astatine, atomic number Z = 85, mass number A = 252).

  10. Atomic Mass and Nuclear Binding Energy for At-236 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-236 (Astatine, atomic number Z = 85, mass number A = 236).

  11. Atomic Mass and Nuclear Binding Energy for At-242 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-242 (Astatine, atomic number Z = 85, mass number A = 242).

  12. Atomic Mass and Nuclear Binding Energy for At-233 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-233 (Astatine, atomic number Z = 85, mass number A = 233).

  13. Atomic Mass and Nuclear Binding Energy for At-221 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-221 (Astatine, atomic number Z = 85, mass number A = 221).

  14. Atomic Mass and Nuclear Binding Energy for At-225 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-225 (Astatine, atomic number Z = 85, mass number A = 225).

  15. Atomic Mass and Nuclear Binding Energy for At-262 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-262 (Astatine, atomic number Z = 85, mass number A = 262).

  16. Atomic Mass and Nuclear Binding Energy for At-279 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-279 (Astatine, atomic number Z = 85, mass number A = 279).

  17. Atomic Mass and Nuclear Binding Energy for At-277 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-277 (Astatine, atomic number Z = 85, mass number A = 277).

  18. Atomic Mass and Nuclear Binding Energy for At-250 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-250 (Astatine, atomic number Z = 85, mass number A = 250).

  19. Atomic Mass and Nuclear Binding Energy for At-232 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-232 (Astatine, atomic number Z = 85, mass number A = 232).

  20. Atomic Mass and Nuclear Binding Energy for At-253 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-253 (Astatine, atomic number Z = 85, mass number A = 253).

  1. Atomic Mass and Nuclear Binding Energy for At-244 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-244 (Astatine, atomic number Z = 85, mass number A = 244).

  2. Atomic Mass and Nuclear Binding Energy for At-259 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-259 (Astatine, atomic number Z = 85, mass number A = 259).

  3. Atomic Mass and Nuclear Binding Energy for At-235 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-235 (Astatine, atomic number Z = 85, mass number A = 235).

  4. Atomic Mass and Nuclear Binding Energy for At-249 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-249 (Astatine, atomic number Z = 85, mass number A = 249).

  5. Atomic Mass and Nuclear Binding Energy for At-239 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-239 (Astatine, atomic number Z = 85, mass number A = 239).

  6. Atomic Mass and Nuclear Binding Energy for At-263 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-263 (Astatine, atomic number Z = 85, mass number A = 263).

  7. Atomic Mass and Nuclear Binding Energy for At-268 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-268 (Astatine, atomic number Z = 85, mass number A = 268).

  8. Atomic Mass and Nuclear Binding Energy for At-274 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-274 (Astatine, atomic number Z = 85, mass number A = 274).

  9. Atomic Mass and Nuclear Binding Energy for At-231 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-231 (Astatine, atomic number Z = 85, mass number A = 231).

  10. Atomic Mass and Nuclear Binding Energy for At-241 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-241 (Astatine, atomic number Z = 85, mass number A = 241).

  11. Atomic Mass and Nuclear Binding Energy for At-257 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-257 (Astatine, atomic number Z = 85, mass number A = 257).

  12. Atomic Mass and Nuclear Binding Energy for At-266 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-266 (Astatine, atomic number Z = 85, mass number A = 266).

  13. Atomic Mass and Nuclear Binding Energy for At-220 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-220 (Astatine, atomic number Z = 85, mass number A = 220).

  14. Atomic Mass and Nuclear Binding Energy for At-265 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-265 (Astatine, atomic number Z = 85, mass number A = 265).

  15. Atomic Mass and Nuclear Binding Energy for At-251 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-251 (Astatine, atomic number Z = 85, mass number A = 251).

  16. Atomic Mass and Nuclear Binding Energy for At-226 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-226 (Astatine, atomic number Z = 85, mass number A = 226).

  17. Atomic Mass and Nuclear Binding Energy for At-260 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-260 (Astatine, atomic number Z = 85, mass number A = 260).

  18. Atomic Mass and Nuclear Binding Energy for At-276 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-276 (Astatine, atomic number Z = 85, mass number A = 276).

  19. Atomic Mass and Nuclear Binding Energy for At-243 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-243 (Astatine, atomic number Z = 85, mass number A = 243).

  20. Atomic Mass and Nuclear Binding Energy for At-216 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-216 (Astatine, atomic number Z = 85, mass number A = 216).

  1. Atomic Mass and Nuclear Binding Energy for At-229 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-229 (Astatine, atomic number Z = 85, mass number A = 229).

  2. Atomic Mass and Nuclear Binding Energy for At-246 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-246 (Astatine, atomic number Z = 85, mass number A = 246).

  3. Atomic Mass and Nuclear Binding Energy for At-214 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-214 (Astatine, atomic number Z = 85, mass number A = 214).

  4. Atomic Mass and Nuclear Binding Energy for At-272 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-272 (Astatine, atomic number Z = 85, mass number A = 272).

  5. Atomic Mass and Nuclear Binding Energy for At-267 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-267 (Astatine, atomic number Z = 85, mass number A = 267).

  6. Atomic Mass and Nuclear Binding Energy for At-285 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-285 (Astatine, atomic number Z = 85, mass number A = 285).

  7. Atomic Mass and Nuclear Binding Energy for At-237 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-237 (Astatine, atomic number Z = 85, mass number A = 237).

  8. Atomic Mass and Nuclear Binding Energy for At-255 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-255 (Astatine, atomic number Z = 85, mass number A = 255).

  9. Atomic Mass and Nuclear Binding Energy for At-269 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-269 (Astatine, atomic number Z = 85, mass number A = 269).

  10. Atomic Mass and Nuclear Binding Energy for At-264 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-264 (Astatine, atomic number Z = 85, mass number A = 264).

  11. Atomic Mass and Nuclear Binding Energy for At-219 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-219 (Astatine, atomic number Z = 85, mass number A = 219).

  12. Atomic Mass and Nuclear Binding Energy for At-247 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-247 (Astatine, atomic number Z = 85, mass number A = 247).

  13. Atomic Mass and Nuclear Binding Energy for At-256 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-256 (Astatine, atomic number Z = 85, mass number A = 256).

  14. Atomic Mass and Nuclear Binding Energy for At-240 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-240 (Astatine, atomic number Z = 85, mass number A = 240).

  15. Atomic Mass and Nuclear Binding Energy for At-215 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-215 (Astatine, atomic number Z = 85, mass number A = 215).

  16. Atomic Mass and Nuclear Binding Energy for At-234 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-234 (Astatine, atomic number Z = 85, mass number A = 234).

  17. Atomic Mass and Nuclear Binding Energy for At-217 (Astatine)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope At-217 (Astatine, atomic number Z = 85, mass number A = 217).

  18. Spectroscopy of low-lying states in neutron-deficient astatine and francium nuclei

    NASA Astrophysics Data System (ADS)

    Jakobsson, U.; Uusitalo, J.; Auranen, K.; Badran, H.; Cederwall, B.; Cox, D. M.; Grahn, T.; Greenlees, P. T.; Julin, R.; Juutinen, S.; HerzáÅ, A.; Konki, J.; Leino, M.; Mallaburn, M.; Pakarinen, J.; Papadakis, P.; Partanen, J.; Rahkila, P.; Sandzelius, M.; Sarén, J.; Scholey, C.; Sorri, J.; Stolze, S.

    2015-10-01

    Low-lying states in neutron-deficient astatine and francium nuclei have been studied by means of in-beam and delayed spectroscopy. The 13/2+ state has been observed in francium nuclei with a similar down-sloping trend as in neighbouring astatine and bismuth isotopes, as a function of decreasing neutron number. A systematic trend can also now be seen for the 1/2+ state both in astatine and francium nuclei, where the level energy decreases steeply as a function of neutron number when moving further away from the neutron shell closure. This trend is very similar between astatine nuclei and their francium isotones. Moreover, shape coexistence has been observed between the 13/2+ state and the spherical 9/2- ground state in 203Fr and 205Fr.

  19. Spectroscopy of low-lying states in neutron-deficient astatine and francium nuclei

    SciTech Connect

    Jakobsson, U. Cederwall, B.; Uusitalo, J.; Auranen, K.; Badran, H.; Cox, D. M.; Grahn, T.; Greenlees, P. T.; Julin, R.; Juutinen, S.; Herzáň, A.; Konki, J.; Leino, M.; Mallaburn, M.; Pakarinen, J.; Papadakis, P.; Partanen, J.; Rahkila, P.; Sandzelius, M.; Sarén, J.; and others

    2015-10-15

    Low-lying states in neutron-deficient astatine and francium nuclei have been studied by means of in-beam and delayed spectroscopy. The 13/2{sup +} state has been observed in francium nuclei with a similar down-sloping trend as in neighbouring astatine and bismuth isotopes, as a function of decreasing neutron number. A systematic trend can also now be seen for the 1/2{sup +} state both in astatine and francium nuclei, where the level energy decreases steeply as a function of neutron number when moving further away from the neutron shell closure. This trend is very similar between astatine nuclei and their francium isotones. Moreover, shape coexistence has been observed between the 13/2{sup +} state and the spherical 9/2{sup −} ground state in {sup 203}Fr and {sup 205}Fr.

  20. Automated astatination of biomolecules - a stepping stone towards multicenter clinical trials

    NASA Astrophysics Data System (ADS)

    Aneheim, Emma; Albertsson, Per; Bäck, Tom; Jensen, Holger; Palm, Stig; Lindegren, Sture

    2015-07-01

    To facilitate multicentre clinical studies on targeted alpha therapy, it is necessary to develop an automated, on-site procedure for conjugating rare, short-lived, alpha-emitting radionuclides to biomolecules. Astatine-211 is one of the few alpha-emitting nuclides with appropriate chemical and physical properties for use in targeted therapies for cancer. Due to the very short range of the emitted α-particles, this therapy is particularly suited to treating occult, disseminated cancers. Astatine is not intrinsically tumour-specific; therefore, it requires an appropriate tumour-specific targeting vector, which can guide the radiation to the cancer cells. Consequently, an appropriate method is required for coupling the nuclide to the vector. To increase the availability of astatine-211 radiopharmaceuticals for targeted alpha therapy, their production should be automated. Here, we present a method that combines dry distillation of astatine-211 and a synthesis module for producing radiopharmaceuticals into a process platform. This platform will standardize production of astatinated radiopharmaceuticals, and hence, it will facilitate large clinical studies focused on this promising, but chemically challenging, alpha-emitting radionuclide. In this work, we describe the process platform, and we demonstrate the production of both astaine-211, for preclinical use, and astatine-211 labelled antibodies.

  1. Automated astatination of biomolecules--a stepping stone towards multicenter clinical trials.

    PubMed

    Aneheim, Emma; Albertsson, Per; Bäck, Tom; Jensen, Holger; Palm, Stig; Lindegren, Sture

    2015-07-14

    To facilitate multicentre clinical studies on targeted alpha therapy, it is necessary to develop an automated, on-site procedure for conjugating rare, short-lived, alpha-emitting radionuclides to biomolecules. Astatine-211 is one of the few alpha-emitting nuclides with appropriate chemical and physical properties for use in targeted therapies for cancer. Due to the very short range of the emitted α-particles, this therapy is particularly suited to treating occult, disseminated cancers. Astatine is not intrinsically tumour-specific; therefore, it requires an appropriate tumour-specific targeting vector, which can guide the radiation to the cancer cells. Consequently, an appropriate method is required for coupling the nuclide to the vector. To increase the availability of astatine-211 radiopharmaceuticals for targeted alpha therapy, their production should be automated. Here, we present a method that combines dry distillation of astatine-211 and a synthesis module for producing radiopharmaceuticals into a process platform. This platform will standardize production of astatinated radiopharmaceuticals, and hence, it will facilitate large clinical studies focused on this promising, but chemically challenging, alpha-emitting radionuclide. In this work, we describe the process platform, and we demonstrate the production of both astaine-211, for preclinical use, and astatine-211 labelled antibodies.

  2. Astatinated trastuzumab, a putative agent for radionuclide immunotherapy of ErbB2-expressing tumours.

    PubMed

    Persson, M I; Gedda, L; Jensen, H J; Lundqvist, H; Malmström, P-U; Tolmachev, V

    2006-03-01

    The anti-ErbB2 antibody trastuzumab is used for the treatment of patients with advanced breast cancer, resulting in a response rate of 40-60%. Coupling with a cytotoxic nuclide, e.g. alpha-emitting 211At, may further increase tumour response. The tumour-targeting properties of trastuzumab, astatinated using N-succinimidyl-para-(tri-n-methylstannyl)-benzoate, were evaluated and compared with those of radioiodinated trastuzumab in this study. We found that astatinated trastuzumab retains high specificity towards ErbB2. While the immunoreactive fraction of radioiodinated trastuzumab was higher than that of astatinated trastuzumab (76+/-9% versus 54+/-28%), both radioconjugates showed high affinity (KD 0.75+/-0.16 nM versus 1.8+/-0.3 nM). A growth inhibition study indicated a dose-dependent cell deactivation, in which approximately 74 cell-associated astatine decays per cell gave a survival fraction of 4.5+/-0.8x10(-4). Results of a comparative animal study on normal mice gave no indication that astatination would have any adverse effects on the biodistribution of the antibody. In conclusion, the results of the study suggest that astatinated trastuzumab is a promising candidate for treating ErbB2-expressing tumours.

  3. Automated astatination of biomolecules – a stepping stone towards multicenter clinical trials

    PubMed Central

    Aneheim, Emma; Albertsson, Per; Bäck, Tom; Jensen, Holger; Palm, Stig; Lindegren, Sture

    2015-01-01

    To facilitate multicentre clinical studies on targeted alpha therapy, it is necessary to develop an automated, on-site procedure for conjugating rare, short-lived, alpha-emitting radionuclides to biomolecules. Astatine-211 is one of the few alpha-emitting nuclides with appropriate chemical and physical properties for use in targeted therapies for cancer. Due to the very short range of the emitted α-particles, this therapy is particularly suited to treating occult, disseminated cancers. Astatine is not intrinsically tumour-specific; therefore, it requires an appropriate tumour-specific targeting vector, which can guide the radiation to the cancer cells. Consequently, an appropriate method is required for coupling the nuclide to the vector. To increase the availability of astatine-211 radiopharmaceuticals for targeted alpha therapy, their production should be automated. Here, we present a method that combines dry distillation of astatine-211 and a synthesis module for producing radiopharmaceuticals into a process platform. This platform will standardize production of astatinated radiopharmaceuticals, and hence, it will facilitate large clinical studies focused on this promising, but chemically challenging, alpha-emitting radionuclide. In this work, we describe the process platform, and we demonstrate the production of both astaine-211, for preclinical use, and astatine-211 labelled antibodies. PMID:26169786

  4. Theoretical approach to explore the production routes of astatine radionuclides

    NASA Astrophysics Data System (ADS)

    Maiti, Moumita; Lahiri, Susanta

    2009-02-01

    To fulfill the recent thrust of astatine radionuclides in the field of nuclear medicine, various production routes have been explored in the present work. The possible production routes of At209-211 comprise both light- and heavy-ion-induced reactions at the bombarding energy range starting from threshold to a maximum of 100 MeV. Excitation functions of those radionuclides, produced through various production routes, have been calculated by using nuclear reaction model codes TALYS, ALICE91, and PACE-II and are compared with the available measured data. Contributions of various reaction mechanisms, such as direct, pre-equilibrium, and equilibrium reactions, to the total reaction cross section have been studied using the codes. Results show that the equilibrium reaction dominates in all cases over other reaction mechanisms.

  5. Theoretical approach to explore the production routes of astatine radionuclides

    SciTech Connect

    Maiti, Moumita; Lahiri, Susanta

    2009-02-15

    To fulfill the recent thrust of astatine radionuclides in the field of nuclear medicine, various production routes have been explored in the present work. The possible production routes of {sup 209-211}At comprise both light- and heavy-ion-induced reactions at the bombarding energy range starting from threshold to a maximum of 100 MeV. Excitation functions of those radionuclides, produced through various production routes, have been calculated by using nuclear reaction model codes TALYS, ALICE91, and PACE-II and are compared with the available measured data. Contributions of various reaction mechanisms, such as direct, pre-equilibrium, and equilibrium reactions, to the total reaction cross section have been studied using the codes. Results show that the equilibrium reaction dominates in all cases over other reaction mechanisms.

  6. Modeling astatine production in liquid lead-bismuth spallation targets

    NASA Astrophysics Data System (ADS)

    David, J. C.; Boudard, A.; Cugnon, J.; Ghali, S.; Leray, S.; Mancusi, D.; Zanini, L.

    2013-03-01

    Astatine isotopes can be produced in liquid lead-bismuth eutectic targets through proton-induced double charge exchange reactions on bismuth or in secondary helium-induced interactions. Models implemented into the most common high-energy transport codes generally have difficulties to correctly estimate their production yields as was shown recently by the ISOLDE Collaboration, which measured release rates from a lead-bismuth target irradiated by 1.4 and 1 GeV protons. In this paper, we first study the capability of the new version of the Liège intranuclear cascade model, INCL4.6, coupled to the deexcitation code ABLA07 to predict the different elementary reactions involved in the production of such isotopes through a detailed comparison of the model with the available experimental data from the literature. Although a few remaining deficiencies are identified, very satisfactory results are found, thanks in particular to improvements brought recently on the treatment of low-energy helium-induced reactions. The implementation of the models into MCNPX allows identifying the respective contributions of the different possible reaction channels in the ISOLDE case. Finally, the full simulation of the ISOLDE experiment is performed, taking into account the likely rather long diffusion time from the target, and compared with the measured diffusion rates for the different astatine isotopes, at the two studied energies, 1.4 and 1 GeV. The shape of the isotopic distribution is perfectly reproduced as well as the absolute release rates, assuming in the calculation a diffusion time between 5 and 10hours. This work finally shows that our model, thanks to the attention paid to the emission of high-energy clusters and to low-energy cluster induced reactions, can be safely used within MCNPX to predict isotopes with a charge larger than that of the target by two units in spallation targets, and, probably, more generally to isotopes created in secondary reactions induced by composite

  7. 49 CFR 571.218 - Standard No. 218; Motorcycle helmets.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR VEHICLE SAFETY STANDARDS Federal Motor Vehicle Safety Standards § 571.218 Standard No. 218; Motorcycle helmets. Link to an amendment... 2. Retention system means the complete assembly by which the helmet is retained in position on...

  8. 49 CFR 571.218 - Standard No. 218; Motorcycle helmets.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR VEHICLE SAFETY STANDARDS Federal Motor Vehicle Safety Standards § 571.218 Standard No. 218; Motorcycle helmets. S1. Scope. This standard.... Retention system means the complete assembly by which the helmet is retained in position on the head...

  9. 49 CFR 571.218 - Standard No. 218; Motorcycle helmets.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR VEHICLE SAFETY STANDARDS Federal Motor Vehicle Safety Standards § 571.218 Standard No. 218; Motorcycle helmets. S1. Scope. This standard.... Retention system means the complete assembly by which the helmet is retained in position on the head...

  10. 49 CFR 571.218 - Standard No. 218; Motorcycle helmets.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR VEHICLE SAFETY STANDARDS Federal Motor Vehicle Safety Standards § 571.218 Standard No. 218; Motorcycle helmets. Link to an amendment... 2. Retention system means the complete assembly by which the helmet is retained in position on...

  11. 49 CFR 571.218 - Standard No. 218; Motorcycle helmets.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR VEHICLE SAFETY STANDARDS Federal Motor Vehicle Safety Standards § 571.218 Standard No. 218; Motorcycle helmets. S1. Scope. This standard...) at the distance indicated in Table 2. Retention system means the complete assembly by which...

  12. Assessment of an effective quasirelativistic methodology designed to study astatine chemistry in aqueous solution.

    PubMed

    Champion, Julie; Seydou, Mahamadou; Sabatié-Gogova, Andrea; Renault, Eric; Montavon, Gilles; Galland, Nicolas

    2011-09-07

    A cost-effective computational methodology designed to study astatine (At) chemistry in aqueous solution has been established. It is based on two-component spin-orbit density functional theory calculations and solvation calculations using the conductor-like polarizable continuum model in conjunction with specific astatine cavities. Theoretical calculations are confronted with experimental data measured for complexation reactions between metallic forms of astatine (At(+) and AtO(+)) and inorganic ligands (Cl(-), Br(-) and SCN(-)). For each reaction, both 1:1 and 1:2 complexes are evidenced. The experimental trends regarding the thermodynamic constants (K) can be reproduced qualitatively and quantitatively. The mean signed error on computed Log K values is -0.4, which corresponds to a mean signed error smaller than 1 kcal mol(-1) on free energies of reaction. Theoretical investigations show that the reactivity of cationic species of astatine is highly sensitive to spin-orbit coupling and solvent effects. At the moment, the presented computational methodology appears to be the only tool to gain an insight into astatine chemistry at a molecular level.

  13. Reagents for astatination of biomolecules: comparison of the in vivo distribution and stability of some radioiodinated/astatinated benzamidyl and nido-carboranyl compounds.

    PubMed

    Wilbur, D Scott; Chyan, Ming-Kuan; Hamlin, Donald K; Kegley, Brian B; Risler, Reudi; Pathare, Pradip M; Quinn, Janna; Vessella, Robert L; Foulon, Catherine; Zalutsky, Michael; Wedge, Timothy J; Hawthorne, M Frederick

    2004-01-01

    An investigation has been conducted to assess the in vivo stability of a series of astatinated benzamides and astatinated nido-carborane compounds in mice. It was hypothesized that the higher bond strength of boron-astatine bonds in the nido-carboranes might provide increased stability toward in vivo deastatination. Four tri-n-butylstannylbenzamides were prepared for radiohalogenation and evaluation in vivo. Those compounds were N-propyl-4-(tri-n-butylstannyl)benzamide 1a, N-propyl-3-(tri-n-butylstannyl)benzamide 2a, ethyl 4-tri-n-butylstannylhippurate 3a, and 4-tri-n-butylstannyl-hippuric acid 4a. Seven mono-nido-carboranyl derivatives were prepared for radiohalogenation and in vivo evaluation. Four of the seven mono-carboranyl derivatives (5a, 6a, 7a, 13a) contained a 3-(nido-carboranyl)propionamide functionality, and the remaining compounds (8a, 8g, 10a) contained a 4-(nido-carboranyl)aniline functionality. Two additional derivatives (11a, 12a) were prepared that contained bis-(nido-carboranylmethyl)benzene moieties (also referred to as Venus flytrap complexes (VFCs). All benzamide and nido-carborane compounds underwent facile iodination and radiohalogenation, except a 4-(nido-carboranyl)aniline derivative, 8a. Iodination of 8a resulted in a mixture, of which the desired iodinated product was a minor component. Therefore, radiohalogenation was not attempted. It is believed that the mixture of products is due to the presence of a thiourea bond. Previous studies have shown that thiourea bonds can interfere with halogenation reactions. In vivo comparisons of the compounds were conducted by co-injection of dual labeled (125/131I and 211At) compounds. Tissue distribution data were obtained at 1 and 4 h postinjection of the radiolabeled compounds, as that was sufficient to determine if astatine was being released. Stability of the astatinated compound was assessed by the difference in concentration of radioiodine and astatine in lung and spleen. All of the benzamides

  14. Microdosimetric model of astatine-211 labeled antibodies for radioimmunotherapy

    SciTech Connect

    Humm, J.L.

    1987-11-01

    Astatine-211 is an alpha-emitter with a short half-life (7.2 hr). This paper discusses the potential of /sup 211/At targeted by antibodies for tumor therapy and the possible advantage of /sup 211/At over beta- and gamma-emitting radionuclides such as /sup 131/I currently employed in the field of radioimmunotherapy. Since the longest range alpha-particle from /sup 211/At is only 67 microns and the rate of energy loss is high (track averaged linear energy transfer LT approximately 120 keV/micron), a disintegration of /sup 211/At produces a large and extremely localized deposition of energy. A Monte-Carlo model has been developed for studying the stochastic fluctuation of alpha-particle hits and energy deposition in cell nuclei in an attempt to determine the efficacy of /sup 211/At-labeled antibodies for tumor cell inactivation. Calculations have been performed for 2 extreme conditions: (a) the case of /sup 211/At retained in the capillary, and (b) for a homogeneous distribution of /sup 211/At-labeled antibody in the tumor. The results of these two calculations represent the boundary conditions between which any real solution must lie. Finally, developments to the model to include antibody transport across the capillary membrane and through the tumor tissue are discussed.

  15. Astatine standard redox potentials and speciation in acidic medium.

    PubMed

    Champion, J; Alliot, C; Renault, E; Mokili, B M; Chérel, M; Galland, N; Montavon, G

    2010-01-14

    A combined experimental and theoretical approach is used to define astatine (At) speciation in acidic aqueous solution and to answer the two main questions raised from literature data: does At(0) exist in aqueous solution and what is the chemical form of At(+III), if it exists. The experimental approach considers that a given species is characterized by its distribution coefficient (D) experimentally determined in a biphasic system. The change in speciation arising from a change in experimental conditions is observed by a change in D value. The theoretical approach involves quasi-relativistic quantum chemistry calculations. The results show that At at the oxidation state 0 cannot exist in aqueous solution. The three oxidation states present in the range of water stability are At(-I), At(+I), and At(+III) and exist as At(-), At(+), and AtO(+), respectively, in the 1-2 pH range. The standard redox potentials of the At(+)/At(-) and AtO(+)/At(+) couples have been determined, the respective values being 0.36 +/- 0.01 and 0.74 +/- 0.01 V vs NHE.

  16. Feasibility of the radioastatination of a monoclonal antibody with astatine-211 purified by wet extraction.

    PubMed

    Bourgeois, Mickaël; Guerard, François; Alliot, Cyrille; Mougin-Degraef, Marie; Rajérison, Holisoa; Remaud-Le Saëc, Patricia; Gestin, Jean-François; Davodeau, François; Chérel, Michel; Barbet, Jacques; Faivre-Chauvet, Alain

    2008-10-15

    Astatine-211, a most promising α-particle emitter for targeted radiotherapy, is generally obtained by high-temperature distillation. However, a liquid-liquid extraction procedure (wet extraction) has also been described. The purpose of this study was to develop and optimize the labelling of the stannylated-activated ester N-hydroxysuccinimidyl-meta-trimethylstannylbenzoate ester (MeSTB) with astatine-211 extracted in di-isopropylether (DIPE) in the presence of the oxidant N-chlorosuccinimide (NCS). The effect of final volume, incubation duration and NCS amounts on radiolabelling yield was studied. The best yields (85-90%) of N-hydroxysuccinimidyl-meta-[(211)At]astatobenzoate ester (SAB) were obtained with 20 nmol of MeSTB, 100 nmol of NCS in 120 µL of DIPE after 15 min. The astatine-211-labelled-activated ester was then used to radiolabel a monoclonal antibody (mAb). The labelling yield was 20-25% and the radiochemical purity was 97-99%. These results show that mAbs may be efficiently labelled with astatine-211 obtained by wet extraction, a fully automatable technique that may prove to be a useful alternative to dry distillation for high activity labelling of radiopharmaceuticals. Copyright © 2008 John Wiley & Sons, Ltd.

  17. Nuclear Data Sheets for A = 218

    SciTech Connect

    Jain, Ashok K.; Singh, Balraj

    2006-04-15

    Nuclear spectroscopic information for known nuclides of mass number 218 (Bi,Po,At,Rn,Fr,Ra,Ac,Th,Pa,U) with Z = 83 to 92 and N = 135 to 126 have been evaluated and presented together with adopted energies and J{pi} of levels in these nuclei. No excited state data are yet available for {sup 218}Bi, {sup 218}At and {sup 218}Pa. Octupole structures are known in {sup 218}Rn, {sup 218}Fr, {sup 218}Ra and {sup 218}Ac nuclides. Since the previous update (1995El08) about ten years ago, many new data are available e.g. decays of {sup 218}Bi to {sup 218}Po, {sup 222}Ra to {sup 218}Rn and {sup 222}Th to {sup 218}Ra; high-spin structures in {sup 218}Rn and {sup 218}Fr; and lifetimes of excited states in {sup 218}Ra. This evaluation supersedes previous full evaluations of A = 218 published by 1987El12 and 1977To13; and an interim evaluation published in 'update' mode by 1995El08 with literature cutoff date of August 1995.

  18. Dry-distillation of astatine-211 from irradiated bismuth targets: a time-saving procedure with high recovery yields.

    PubMed

    Lindegren, S; Bäck, T; Jensen, H J

    2001-08-01

    Astatine-211 was produced via the 209Bi(alpha,2n) 211At reaction. The radionuclide was isolated with a novel procedure employing dry-distillation of the irradiated target material. The astatine was condensed as a dry residue in a PEEK-capillary cryotrap. Distillation was completed within 1-2 min with isolation yields of 92 +/- 3%. Subsequent work-up of the nuclide resulted in final recovery yields of 79 +/- 3%.

  19. Method for the simultaneous preparation of Radon-211, Xenon-125, Xenon-123, Astatine-211, Iodine-125 and Iodine-123

    DOEpatents

    Mirzadeh, Saed; Lambrecht, Richard M.

    1987-01-01

    A method for simultaneously preparing Radon-211, Astatine-211, Xenon-125, Xenon-123, Iodine-125 and Iodine-123 in a process that includes irradiating a fertile metal material then using a one-step chemical procedure to collect a first mixture of about equal amounts of Radon-211 and Xenon-125, and a separate second mixture of about equal amounts of Iodine-123 and Astatine-211.

  20. 50 CFR 218.3 - Prohibitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Marine Mammals Incidental to U.S. Navy Training in the Virginia Capes Range Complex (VACAPES Range Complex) § 218.3 Prohibitions. Notwithstanding takings contemplated in § 218.2 and authorized by a...

  1. 29 CFR 1910.218 - Forging machines.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 5 2014-07-01 2014-07-01 false Forging machines. 1910.218 Section 1910.218 Labor... OCCUPATIONAL SAFETY AND HEALTH STANDARDS Machinery and Machine Guarding § 1910.218 Forging machines. (a... other identifier, for the forging machine which was inspected. (ii) Scheduling and recording...

  2. 29 CFR 1910.218 - Forging machines.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 5 2013-07-01 2013-07-01 false Forging machines. 1910.218 Section 1910.218 Labor... OCCUPATIONAL SAFETY AND HEALTH STANDARDS Machinery and Machine Guarding § 1910.218 Forging machines. (a... other identifier, for the forging machine which was inspected. (ii) Scheduling and recording...

  3. 20 CFR 498.218 - The record.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false The record. 498.218 Section 498.218 Employees... § 498.218 The record. (a) The hearing shall be recorded and transcribed. Transcripts may be obtained following the hearing from the ALJ. (b) The transcript of testimony, exhibits and other evidence admitted...

  4. 20 CFR 218.27 - Vacation pay.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Vacation pay. 218.27 Section 218.27 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD RETIREMENT ACT ANNUITY BEGINNING AND... Beginning Date § 218.27 Vacation pay. (a) From railroad employer. Vacation pay may be credited to...

  5. 30 CFR 218.56 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Definitions. 218.56 Section 218.56 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS AND INCENTIVES Oil and Gas, General § 218.56...

  6. 30 CFR 218.54 - Late payments.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Late payments. 218.54 Section 218.54 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS AND INCENTIVES Oil and Gas, General § 218.54 Late...

  7. 30 CFR 218.105 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Definitions. 218.105 Section 218.105 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS AND INCENTIVES Oil and Gas, Onshore § 218.105...

  8. 42 CFR 438.218 - Enrollee information.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Enrollee information. 438.218 Section 438.218 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES... and Operation Standards § 438.218 Enrollee information. The requirements that States must meet...

  9. 22 CFR 218.24 - Information requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Information requirements. 218.24 Section 218.24... OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Duties of Agency Recipients § 218.24 Information requirements. Each recipient shall: (a) Make available upon request to the agency information necessary...

  10. 49 CFR 218.9 - Civil penalty.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Civil penalty. 218.9 Section 218.9 Transportation... TRANSPORTATION RAILROAD OPERATING PRACTICES General § 218.9 Civil penalty. Any person (an entity of any type... requirement of this part or causes the violation of any such requirement is subject to a civil penalty of...

  11. 22 CFR 218.34 - Investigation.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Investigation. 218.34 Section 218.34 Foreign... ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Investigation, Conciliation, and Enforcement Procedures § 218.34 Investigation. (a) Informal investigation. (1) The agency will investigate complaints that...

  12. 22 CFR 218.34 - Investigation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Investigation. 218.34 Section 218.34 Foreign... ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Investigation, Conciliation, and Enforcement Procedures § 218.34 Investigation. (a) Informal investigation. (1) The agency will investigate complaints that...

  13. 22 CFR 218.34 - Investigation.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Investigation. 218.34 Section 218.34 Foreign... ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Investigation, Conciliation, and Enforcement Procedures § 218.34 Investigation. (a) Informal investigation. (1) The agency will investigate complaints that...

  14. 22 CFR 218.34 - Investigation.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Investigation. 218.34 Section 218.34 Foreign... ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Investigation, Conciliation, and Enforcement Procedures § 218.34 Investigation. (a) Informal investigation. (1) The agency will investigate complaints that...

  15. 10 CFR 218.40 - Investigations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false Investigations. 218.40 Section 218.40 Energy DEPARTMENT OF ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION Investigations, Violations, Sanctions and Judicial Actions § 218.40 Investigations. (a) The DOE may initiate and conduct investigations relating...

  16. 10 CFR 218.40 - Investigations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 3 2012-01-01 2012-01-01 false Investigations. 218.40 Section 218.40 Energy DEPARTMENT OF ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION Investigations, Violations, Sanctions and Judicial Actions § 218.40 Investigations. (a) The DOE may initiate and conduct investigations relating...

  17. 10 CFR 218.40 - Investigations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Investigations. 218.40 Section 218.40 Energy DEPARTMENT OF ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION Investigations, Violations, Sanctions and Judicial Actions § 218.40 Investigations. (a) The DOE may initiate and conduct investigations relating...

  18. 49 CFR 218.93 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Definitions. 218.93 Section 218.93 Transportation... TRANSPORTATION RAILROAD OPERATING PRACTICES Handling Equipment, Switches, and Fixed Derails § 218.93 Definitions... manipulation. For purposes of this subpart, a hand-operated switch does not include switches operated by...

  19. 28 CFR 2.218 - Revocation decisions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Revocation decisions. 2.218 Section 2.218..., YOUTH OFFENDERS, AND JUVENILE DELINQUENTS District of Columbia Supervised Releasees § 2.218 Revocation... revocation), a further term of supervised release imposed by the Commission under this paragraph shall...

  20. 29 CFR 1910.218 - Forging machines.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 5 2011-07-01 2011-07-01 false Forging machines. 1910.218 Section 1910.218 Labor... OCCUPATIONAL SAFETY AND HEALTH STANDARDS Machinery and Machine Guarding § 1910.218 Forging machines. (a... other identifier, for the forging machine which was inspected. (ii) Scheduling and recording...

  1. 31 CFR 800.218 - Lead agency.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Lead agency. 800.218 Section 800.218... FOREIGN PERSONS Definitions § 800.218 Lead agency. The term lead agency means an agency designated by the... activity for which the Chairperson designates it as a lead agency, including all or a portion of a...

  2. 31 CFR 800.218 - Lead agency.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Lead agency. 800.218 Section 800.218... FOREIGN PERSONS Definitions § 800.218 Lead agency. The term lead agency means an agency designated by the... activity for which the Chairperson designates it as a lead agency, including all or a portion of a...

  3. 31 CFR 800.218 - Lead agency.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Lead agency. 800.218 Section 800.218... FOREIGN PERSONS Definitions § 800.218 Lead agency. The term lead agency means an agency designated by the... activity for which the Chairperson designates it as a lead agency, including all or a portion of a...

  4. 31 CFR 800.218 - Lead agency.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Lead agency. 800.218 Section 800.218... FOREIGN PERSONS Definitions § 800.218 Lead agency. The term lead agency means an agency designated by the... activity for which the Chairperson designates it as a lead agency, including all or a portion of a...

  5. 49 CFR 218.35 - Yard limits.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Yard limits. 218.35 Section 218.35 Transportation... TRANSPORTATION RAILROAD OPERATING PRACTICES Protection of Trains and Locomotives § 218.35 Yard limits. (a) After August 1, 1977, yard limits must be designated by— (1) Yard limit signs, and (2) Timetable, train...

  6. 36 CFR 21.8 - Employee certification.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Employee certification. 21.8 Section 21.8 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR HOT SPRINGS NATIONAL PARK; BATHHOUSE REGULATIONS § 21.8 Employee certification. (a) Employees engaged...

  7. 49 CFR 218.4 - Preemptive effect.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Preemptive effect. 218.4 Section 218.4 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES General § 218.4 Preemptive effect. Normal...

  8. 49 CFR 218.4 - Preemptive effect.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Preemptive effect. 218.4 Section 218.4 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES General § 218.4 Preemptive effect. Normal...

  9. 49 CFR 218.4 - Preemptive effect.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Preemptive effect. 218.4 Section 218.4 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES General § 218.4 Preemptive effect. Normal...

  10. 49 CFR 218.4 - Preemptive effect.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Preemptive effect. 218.4 Section 218.4 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES General § 218.4 Preemptive effect. Normal...

  11. 49 CFR 218.4 - Preemptive effect.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Preemptive effect. 218.4 Section 218.4 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES General § 218.4 Preemptive effect. Normal...

  12. 49 CFR 218.9 - Civil penalty.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Civil penalty. 218.9 Section 218.9 Transportation... TRANSPORTATION RAILROAD OPERATING PRACTICES General § 218.9 Civil penalty. Any person (an entity of any type... requirement of this part or causes the violation of any such requirement is subject to a civil penalty of...

  13. 10 CFR 218.10 - Rule.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 3 2012-01-01 2012-01-01 false Rule. 218.10 Section 218.10 Energy DEPARTMENT OF ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION Supply Orders § 218.10 Rule. (a) Upon the determination by the President that an international energy supply emergency exists, firms engaged in...

  14. 10 CFR 218.10 - Rule.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 3 2014-01-01 2014-01-01 false Rule. 218.10 Section 218.10 Energy DEPARTMENT OF ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION Supply Orders § 218.10 Rule. (a) Upon the determination by the President that an international energy supply emergency exists, firms engaged in...

  15. 10 CFR 218.10 - Rule.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 3 2013-01-01 2013-01-01 false Rule. 218.10 Section 218.10 Energy DEPARTMENT OF ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION Supply Orders § 218.10 Rule. (a) Upon the determination by the President that an international energy supply emergency exists, firms engaged in...

  16. 10 CFR 218.10 - Rule.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false Rule. 218.10 Section 218.10 Energy DEPARTMENT OF ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION Supply Orders § 218.10 Rule. (a) Upon the determination by the President that an international energy supply emergency exists, firms engaged in...

  17. 10 CFR 218.10 - Rule.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Rule. 218.10 Section 218.10 Energy DEPARTMENT OF ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION Supply Orders § 218.10 Rule. (a) Upon the determination by the President that an international energy supply emergency exists, firms engaged in...

  18. 10 CFR 218.11 - Supply orders.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false Supply orders. 218.11 Section 218.11 Energy DEPARTMENT OF ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION Supply Orders § 218.11 Supply orders. (a) A...) The DOE shall serve a copy of the supply order on the firm directed to act as stated therein. (c)...

  19. 10 CFR 218.11 - Supply orders.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 3 2013-01-01 2013-01-01 false Supply orders. 218.11 Section 218.11 Energy DEPARTMENT OF ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION Supply Orders § 218.11 Supply orders. (a) A...) The DOE shall serve a copy of the supply order on the firm directed to act as stated therein. (c)...

  20. 20 CFR 498.218 - The record.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false The record. 498.218 Section 498.218 Employees... § 498.218 The record. (a) The hearing shall be recorded and transcribed. Transcripts may be obtained following the hearing from the ALJ. (b) The transcript of testimony, exhibits and other evidence admitted...

  1. 20 CFR 498.218 - The record.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false The record. 498.218 Section 498.218 Employees... § 498.218 The record. (a) The hearing shall be recorded and transcribed. Transcripts may be obtained following the hearing from the ALJ. (b) The transcript of testimony, exhibits and other evidence admitted...

  2. 7 CFR 58.218 - Surge tanks.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Surge tanks. 58.218 Section 58.218 Agriculture....218 Surge tanks. If surge tanks are used for hot milk, and temperatures of product including foam being held in the surge tank during processing, is not maintained at a minimum of 150 °F, then two...

  3. In-source spectroscopy on astatine and radium for resonant laser ionization

    NASA Astrophysics Data System (ADS)

    Raeder, Sebastian; Lassen, Jens; Heggen, Henning; Teigelhöfer, Andrea

    2014-06-01

    At on-line isotope separator facilities, rare isotopes of radioactive elements such as astatine, radium or polonium are demanded for fundamental research on nuclear structure. These elements are generally suitable for a resonance ionization laser ion source, but more data on the atomic structure is necessary to develop efficient laser ionization schemes. Due to the missing stable reference isotopes spectroscopic investigation of the atomic structure can only be performed during on-line operation. At the Isotope Separator and ACcelerator (ISAC) facility at TRIUMF, the elements astatine and radium were investigated by in-source laser spectroscopy to optimize the laser ionization efficiency. For astatine, laser spectroscopy was performed to search for high lying bound states as well as for auto-ionizing resonances. This led to the identification of four new high lying bound states of odd parity, while no auto-ionizing resonances were observed in the investigated region. Furthermore, the feasibility and the impact of laser ionization on the yield of radium isotopes was investigated using an activated target after proton irradiation.

  4. Environmental neutralization of polonium-218

    SciTech Connect

    Goldstein, S.D.; Hopke, P.K.

    1985-01-01

    Previous work has indicated that two mechanisms of neutralization of the singly charged polonium ion exist. Charged Polonium-218 can be neutralized by reacting with oxygen to form a polonium oxide ion with a higher ionization potential than that of the polonium metal and then accepting an electron transferred from a lower ionization potential gas. In this present work, this mechanism has been verified by determining that the polonium oxide has an ionization potential in the range 10.35-10.53 eV. It was also previously reported that /sup 218/Po can be neutralized, in the absence of oxygen, by the scavenging of electrons by a trace gas such as water or nitrogen dioxide and their diffusion to the polonium ion. To verify this second neutralization mechanism, concentrations of nitrogen dioxide in nitrogen in the range of 50 ppb-1 ppm were examined for their ability to neutralize the polonium ion. Complete neutralization of /sup 218/Po was observed at nitrogen dioxide concentrations greater than 700 ppb. For concentrations below 700 ppb, the degree of neutralization was found to increase smoothly with the nitrogen dioxide concentration.

  5. Astatine-211-labeled radiotherapeutics: an emerging approach to targeted alpha-particle radiotherapy.

    PubMed

    Zalutsky, M R; Vaidyanathan, G

    2000-09-01

    Targeted radiotherapy or endoradiotherapy is an appealing approach to cancer treatment because of the potential for delivering curative doses of radiation to tumor while sparing normal tissues. Radionuclides that decay by the emission of alpha-particles such as the heavy halogen astatine-211 (211At) offer the exciting prospect of combining cell-specific molecular targets with radiation having a range in tissue of only a few cell diameters. Herein, the radiobiological advantages of alpha-particle targeted radiotherapy will be reviewed, and the rationale for using 211At for this purpose will be described. The chemistry of astatine is similar to that of iodine; however, there are important differences which make the synthesis and evaluation of 211At-labeled compounds more challenging. Perhaps the most successful approach that has been developed involves the astatodemetallation of tin, silicon or mercury precursors. Astatine-211 labeled agents that have been investigated for targeted radiotherapy include [211At]astatide, 211At- labeled particulates, 211At-labeled naphthoquinone derivatives, 211At-labeled methylene blue, 211At-labeled DNA precursors, meta-[211At]astatobenzylguanidine, 211At-labeled biotin conjugates, 211At-labeled bisphosphonates, and 211At-labeled antibodies and antibody fragments. The status of these 211At-labeled compounds will be discussed in terms of their labeling chemistry, cytotoxicity in cell culture, as well as their tissue distribution and therapeutic efficacy in animal models of human cancers. Finally, an update on the status of the first clinical trial with an 211At-labeled targeted therapeutic, 211At-labeled chimeric anti-tenascin antibody 81C6, will be provided.

  6. 31 CFR 800.218 - Lead agency.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Lead agency. 800.218 Section 800.218 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF INVESTMENT SECURITY, DEPARTMENT OF THE TREASURY REGULATIONS PERTAINING TO MERGERS, ACQUISITIONS, AND TAKEOVERS...

  7. 36 CFR 218.2 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... PREDECISIONAL ADMINISTRATIVE REVIEW PROCESS General Provisions § 218.2 Definitions. The following definitions... of the receiving office on the last day of the filing period (§ 218.6(a)). Objection process. The... transcriptions or other notes from oral statements or presentation. For the purposes of this rule,...

  8. 36 CFR 218.2 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... PREDECISIONAL ADMINISTRATIVE REVIEW PROCESS General Provisions § 218.2 Definitions. The following definitions... of the receiving office on the last day of the filing period (§ 218.6(a)). Objection process. The... transcriptions or other notes from oral statements or presentation. For the purposes of this rule,...

  9. 30 CFR 218.10 - Information collection.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Information collection. 218.10 Section 218.10 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS AND INCENTIVES General Provisions §...

  10. 9 CFR 381.218 - Criminal offenses.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Criminal offenses. 381.218 Section 381... CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS Detention; Seizure and Condemnation; Criminal Offenses § 381.218 Criminal offenses. The Act contains criminal provisions with respect to numerous...

  11. 9 CFR 201.218 - Arbitration.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Arbitration. 201.218 Section 201.218 Animals and Animal Products GRAIN INSPECTION, PACKERS AND STOCKYARDS ADMINISTRATION (PACKERS AND... the contract in bold conspicuous print: “Right to Decline Arbitration. A poultry grower,...

  12. 9 CFR 201.218 - Arbitration.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Arbitration. 201.218 Section 201.218 Animals and Animal Products GRAIN INSPECTION, PACKERS AND STOCKYARDS ADMINISTRATION (PACKERS AND... the contract in bold conspicuous print: “Right to Decline Arbitration. A poultry grower,...

  13. 42 CFR 93.218 - Person.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Person. 93.218 Section 93.218 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH...

  14. 27 CFR 24.218 - Other wine.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Other wine. 24.218 Section... THE TREASURY LIQUORS WINE Production of Other Than Standard Wine § 24.218 Other wine. (a) General. Other than standard wine not included in other sections in this subpart are considered other wine....

  15. 27 CFR 24.218 - Other wine.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Other wine. 24.218 Section... THE TREASURY ALCOHOL WINE Production of Other Than Standard Wine § 24.218 Other wine. (a) General. Other than standard wine not included in other sections in this subpart are considered other wine....

  16. 27 CFR 24.218 - Other wine.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Other wine. 24.218 Section... THE TREASURY LIQUORS WINE Production of Other Than Standard Wine § 24.218 Other wine. (a) General. Other than standard wine not included in other sections in this subpart are considered other wine....

  17. 27 CFR 24.218 - Other wine.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Other wine. 24.218 Section... THE TREASURY LIQUORS WINE Production of Other Than Standard Wine § 24.218 Other wine. (a) General. Other than standard wine not included in other sections in this subpart are considered other wine....

  18. 27 CFR 24.218 - Other wine.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Other wine. 24.218 Section... THE TREASURY ALCOHOL WINE Production of Other Than Standard Wine § 24.218 Other wine. (a) General. Other than standard wine not included in other sections in this subpart are considered other wine....

  19. 22 CFR 218.11 - Standards.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Standards. 218.11 Section 218.11 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT NONDISCRIMINATION ON THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Standards for Determining Age Discrimination §...

  20. 48 CFR 52.218 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false 52.218 Section 52.218 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses...

  1. 7 CFR 1430.218 - Assignments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Assignments. 1430.218 Section 1430.218 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS DAIRY PRODUCTS Milk Income Loss Contract Program §...

  2. 10 CFR 218.43 - Injunctions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false Injunctions. 218.43 Section 218.43 Energy DEPARTMENT OF ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION Investigations, Violations, Sanctions and... appropriate district court of the United States to enjoin such acts or practices and, upon a proper showing,...

  3. 30 CFR 218.153 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 3 2012-07-01 2012-07-01 false 218.153 Section 218.153 Mineral Resources OFFICE OF NATURAL RESOURCES REVENUE, DEPARTMENT OF THE INTERIOR NATURAL RESOURCES REVENUE COLLECTION OF ROYALTIES, RENTALS, BONUSES, AND OTHER MONIES DUE THE FEDERAL GOVERNMENT Oil, Gas and Sulfur, Offshore §...

  4. 42 CFR 57.218 - Noncompliance.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Noncompliance. 57.218 Section 57.218 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR CONSTRUCTION OF TEACHING FACILITIES, EDUCATIONAL IMPROVEMENTS, SCHOLARSHIPS AND STUDENT LOANS Health Professions Student Loans §...

  5. 42 CFR 57.218 - Noncompliance.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Noncompliance. 57.218 Section 57.218 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR CONSTRUCTION OF TEACHING FACILITIES, EDUCATIONAL IMPROVEMENTS, SCHOLARSHIPS AND STUDENT LOANS Health Professions Student Loans §...

  6. 42 CFR 57.218 - Noncompliance.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Noncompliance. 57.218 Section 57.218 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR CONSTRUCTION OF TEACHING FACILITIES, EDUCATIONAL IMPROVEMENTS, SCHOLARSHIPS AND STUDENT LOANS Health Professions Student Loans §...

  7. 42 CFR 57.218 - Noncompliance.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Noncompliance. 57.218 Section 57.218 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR CONSTRUCTION OF TEACHING FACILITIES, EDUCATIONAL IMPROVEMENTS, SCHOLARSHIPS AND STUDENT LOANS Health Professions Student Loans §...

  8. 49 CFR 218.23 - Blue signal display.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Blue signal display. 218.23 Section 218.23... signal display. (a) Blue signals displayed in accordance with § 218.25, 218.27, or 218.29 signify that workers are on, under, or between rolling equipment. When so displayed— (1) The equipment may not...

  9. 49 CFR 218.23 - Blue signal display.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Blue signal display. 218.23 Section 218.23... signal display. (a) Blue signals displayed in accordance with § 218.25, 218.27, or 218.29 signify that workers are on, under, or between rolling equipment. When so displayed— (1) The equipment may not...

  10. 49 CFR 218.23 - Blue signal display.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Blue signal display. 218.23 Section 218.23... signal display. (a) Blue signals displayed in accordance with § 218.25, 218.27, or 218.29 signify that workers are on, under, or between rolling equipment. When so displayed— (1) The equipment may not...

  11. 49 CFR 218.23 - Blue signal display.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Blue signal display. 218.23 Section 218.23... signal display. (a) Blue signals displayed in accordance with § 218.25, 218.27, or 218.29 signify that workers are on, under, or between rolling equipment. When so displayed— (1) The equipment may not...

  12. 49 CFR 218.23 - Blue signal display.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Blue signal display. 218.23 Section 218.23... signal display. (a) Blue signals displayed in accordance with § 218.25, 218.27, or 218.29 signify that workers are on, under, or between rolling equipment. When so displayed— (1) The equipment may not...

  13. Astatine-211 labeling of an anti-melanoma antibody and its Fab fragment using N-succinimidyl para[{sup 211} At]astatobenzoate : comparisons In Vivo with the para-[{sup 125}1]iodobenzoyl conjugate.

    SciTech Connect

    Hadley, S. W.; Wilbur, D. S.; Gray, M. A.; Atcher, R. W.; Chemistry; NeoRx Corp.; Univ. of Washington Medical Center

    1991-01-01

    Astatine-211 labeling of an anti-melanoma antibody, NR-ML-05, and its Fab fragment using N-succinimidyl para[{sup 211} At]astatobenzoate has been described. Preparation of the astatinated intermediate 2a was accomplished by distilling astatine-211 from an irradiated bismuth target directly into a reaction mixture containing an organometallic compound, N-succinimidyl p-(tri-n-butylstannyl)benzoate (1), and an oxidant, N-chlorosuccinimide, in 5% HOAc/MeOH. Trapping of distilled astatine as 2a was found to be efficient, resulting in 70-90% yields based on the amount of astatine-211 which ranged from 20% to 75%. Conjugation of 2a to NR-ML-05 and its Fab fragment was accomplished in 40-60% yields. The [{sup 211}At]astatobenzoyl-conjugated antibodies were found to be stable in vitro when challenged by strong denaturants and nucleophilic reagents. Coinjected dual-labeled studies of the 2a astatinated antibodies and the same antibodies labeled with N-succinimidyl p-[{sup 125}I]iodobenzoate (2b) in athymic mice bearing the human tumor xenograft A375 Met/Mix demonstrated that both radiolabeled antibodies had equivalent tumor localization. Data from the dual-labeled biodistribution of the intact antibody suggests that the astatine is stably attached. Data from the dual-labeled Fab fragment suggests that a portion of the astatine label is released as astatide, either from the astatinated Fab or from a catabolite.

  14. Production of [(211)At]-astatinated radiopharmaceuticals and applications in targeted α-particle therapy.

    PubMed

    Guérard, François; Gestin, Jean-François; Brechbiel, Martin W

    2013-02-01

    (211)At is a promising radionuclide for α-particle therapy of cancers. Its physical characteristics make this radionuclide particularly interesting to consider when bound to cancer-targeting biomolecules for the treatment of microscopic tumors. (211)At is produced by cyclotron irradiation of (209)Bi with α-particles accelerated at ~28 MeV and can be obtained in high radionuclidic purity after isolation from the target. Its chemistry resembles iodine, but there is also a tendency to behave as a metalloid. However, the chemical behavior of astatine has not yet been clearly established, primarily due to the lack of any stable isotopes of this element, which precludes the use of conventional analytical techniques for its characterization. There are also only a limited number of research centers that have been able to produce this element in sufficient amounts to carry out extensive investigations. Despite these difficulties, chemical reactions typically used with iodine can be performed, and a number of biomolecules of interest have been labeled with (211)At. However, most of these compounds exhibit unacceptable instability in vivo due to the weakness of the astatine-biomolecule bond. Nonetheless, several compounds have shown high potential for the treatment of cancers in vitro and in several animal models, thus providing a promising basis that has allowed initiation of the first two clinical studies.

  15. Environmental properties of polonium-218

    SciTech Connect

    Goldstein, S.D.

    1983-01-01

    An investigation was undertaken of the atmospheric chemistry of the radon decay product polonium-218. Previous work has indicated that two mechanisms of neutralization of the singly charged ion exist. Charged RaA can be neutralized by reacting with oxygen to form a polonium oxide ion that has a higher ionization potential than that of the polonium metal, and then accepting an electron transferred from a lower ionization potential gas. It was been determined that the polonium dioxide has an ionization potential in the range of 10.35 to 10.53 eV. It has also been determined that RaA can be neutralized, in the absence of oxygen, from the scavenging of electrons by a trace gas such as water or nitrogen dioxide and the diffusion to the polonium ion. To verify the presence of the second neutralization mechanism, nitrogen dioxide in nitrogen concentrations in the range of 1 ppM to 50 ppB were examined. Complete neutralization of RaA was observed at nitrogen dioxide concentrations greater than 700 ppB. For concentrations less than 700 ppB, the degree of neutralization was found to decrease. 12 references, 3 figures, 8 tables.

  16. Nuclear data sheets update for A = 218

    SciTech Connect

    Akovali, Y. A.

    1995-11-01

    The available nuclear structure information for all nuclei with mass number A = 218 is presented. Various decay and reaction data are evaluated and compared. Adopted data, levels, spin, parity and configuration assignments are given.

  17. 50 CFR 218.241 - Adaptive management.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Low Frequency Active (SURTASS LFA) Sonar § 218.241 Adaptive management. NMFS may modify (including...) Results from the Navy's monitoring from the previous year's operation of SURTASS LFA sonar. (b)...

  18. 50 CFR 218.241 - Adaptive management.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Low Frequency Active (SURTASS LFA) Sonar § 218.241 Adaptive management. NMFS may modify (including...) Results from the Navy's monitoring from the previous year's operation of SURTASS LFA sonar. (b)...

  19. 36 CFR 218.13 - Secretary's authority.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Authorized by the Healthy Forests Restoration Act of 2003 § 218.13 Secretary's authority. (a) Nothing in this... Environment, are not subject to the procedures set forth in this subpart. A decision by the Secretary or...

  20. 50 CFR 218.231 - Effective dates.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... and Importing of Marine Mammals; Navy Operations of Surveillance Towed Array Sensor System Low Frequency Active (SURTASS LFA) Sonar § 218.231 Effective dates. Regulations are effective August 15,...

  1. 50 CFR 218.231 - Effective dates.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... and Importing of Marine Mammals; Navy Operations of Surveillance Towed Array Sensor System Low Frequency Active (SURTASS LFA) Sonar § 218.231 Effective dates. Regulations are effective August 15,...

  2. 50 CFR 218.231 - Effective dates.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... and Importing of Marine Mammals; Navy Operations of Surveillance Towed Array Sensor System Low Frequency Active (SURTASS LFA) Sonar § 218.231 Effective dates. Regulations are effective August 15,...

  3. Investigation of astatine(III) hydrolyzed species: experiments and relativistic calculations.

    PubMed

    Champion, Julie; Sabatié-Gogova, Andréa; Bassal, Fadel; Ayed, Tahra; Alliot, Cyrille; Galland, Nicolas; Montavon, Gilles

    2013-03-07

    This work aims to resolve some controversies about astatine(III) hydroxide species present in oxidant aqueous solution. AtO(+) is the dominant species existing under oxidizing and acidic pH conditions. This is consistent with high-performance ion-exchange chromatography data showing the existence of one species holding one positive charge. A change in speciation occurs as the pH changes from 1 to 4, while remaining under oxidizing conditions. Dynamic experiments with ion-exchange resins evidence the existence of a neutral species witnessed by its elution in the void volume. Batch-experiments using a competition method show the exchange of one proton indicating the formation of the AtO(OH) species. The hydrolysis thermodynamic constant, extrapolated to zero ionic strength, was determined to be 10(-1.9). This value is supported by two-component relativistic quantum calculations and therefore allows disclosing unambiguously the structure of the formed species.

  4. Complexation study on no-carrier-added astatine with insulin: a candidate radiopharmaceutical.

    PubMed

    Lahiri, Susanta; Roy, Kamalika; Sen, Souvik

    2008-12-01

    No-carrier-added astatine radionuclides produced in the (7)Li-irradiated lead matrix were separated from bulk lead nitrate target by complexing At with insulin, followed by dialysis. The method offers simultaneous separation of At from lead as well as its complexation with insulin. The At-insulin complex might be a potential radiopharmaceutical in the treatment of hepatocellular carcinoma. The stability of At-insulin complex was checked by dialysis against deionized water and Ringer lactate (RL) solution. It has been found that the half-life of At-insulin complex is about approximately 12h, when dialyzed against deionized water and is only 6h, when dialyzed against RL solution having the same composition as blood serum. The 6h half-life of this Insulin-At complex is perfect for killing cancer cells from external cell surfaces as the half-life of internalization of insulin molecule inside the cell is 7-12h.

  5. 50 CFR 218.174 - Requirements for monitoring and reporting.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... chapter and § 218.176 for activities described in § 218.170(c) is required to cooperate with the NMFS when... § 218.170(c) is thought to have resulted in the mortality or injury of any marine mammals, or in any take of marine mammals not identified or authorized in § 218.171(c). (c) The Navy must conduct...

  6. 10 CFR 218.40 - Investigations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... the DOE at any time that circumstances so warrant. ... Judicial Actions § 218.40 Investigations. (a) The DOE may initiate and conduct investigations relating to... the DOE or any order promulgated by the DOE under the authority of section 251 of EPCA, or any...

  7. 13 CFR 134.218 - Judges.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... OFFICE OF HEARINGS AND APPEALS Rules of Practice for Most Cases § 134.218 Judges. (a) Assignment. The AA... Administrative Law Judge. The AA/OHA will assign all other cases before OHA to either an Administrative Law Judge or an Administrative Judge, or, if the AA/OHA is a duly licensed attorney, to himself or herself....

  8. 10 CFR 218.3 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION General Provisions § 218.3 Definitions. DOE... Act (Pub. L. 94-163), as amended. Firm means any association, company, corporation, estate, individual... International Energy Agency established to implement the IEP. IEP means the International Energy...

  9. 10 CFR 218.3 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION General Provisions § 218.3 Definitions. DOE... Act (Pub. L. 94-163), as amended. Firm means any association, company, corporation, estate, individual... International Energy Agency established to implement the IEP. IEP means the International Energy...

  10. 10 CFR 218.3 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION General Provisions § 218.3 Definitions. DOE... Act (Pub. L. 94-163), as amended. Firm means any association, company, corporation, estate, individual... International Energy Agency established to implement the IEP. IEP means the International Energy...

  11. 10 CFR 218.3 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION General Provisions § 218.3 Definitions. DOE... Act (Pub. L. 94-163), as amended. Firm means any association, company, corporation, estate, individual... International Energy Agency established to implement the IEP. IEP means the International Energy...

  12. 10 CFR 218.3 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION General Provisions § 218.3 Definitions. DOE... Act (Pub. L. 94-163), as amended. Firm means any association, company, corporation, estate, individual... International Energy Agency established to implement the IEP. IEP means the International Energy...

  13. 49 CFR 218.93 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... TRANSPORTATION RAILROAD OPERATING PRACTICES Handling Equipment, Switches, and Fixed Derails § 218.93 Definitions... clearance point shall accommodate a person riding the side of a car. Correspondence of crossover switches means both crossover switches are lined for the crossover or both are lined for the straight...

  14. 49 CFR 218.93 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... TRANSPORTATION RAILROAD OPERATING PRACTICES Handling Equipment, Switches, and Fixed Derails § 218.93 Definitions... clearance point shall accommodate a person riding the side of a car. Correspondence of crossover switches means both crossover switches are lined for the crossover or both are lined for the straight...

  15. 49 CFR 218.39 - Hump operations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Protection of Trains and Locomotives § 218.39 Hump operations. After June 30, 1984, each railroad that operates a remote control hump yard facility must have...

  16. 49 CFR 218.39 - Hump operations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Protection of Trains and Locomotives § 218.39 Hump operations. After June 30, 1984, each railroad that operates a remote control hump yard facility must have...

  17. 50 CFR 218.74 - Mitigation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) Mitigation zones for the use of Navy sea lions: (A) If a monk seal is seen approaching or within 100 m of a... and Importing Marine Mammals; U.S. Navy's Hawaii-Southern California Training and Testing (HSTT) § 218...) When marine mammals are visually detected, the Navy shall ensure that low-frequency and...

  18. 7 CFR 58.218 - Surge tanks.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) GRADING AND INSPECTION, GENERAL SPECIFICATIONS FOR APPROVED PLANTS AND STANDARDS FOR GRADES OF DAIRY PRODUCTS 1 General....218 Surge tanks. If surge tanks are used for hot milk, and temperatures of product including...

  19. 7 CFR 58.218 - Surge tanks.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) GRADING AND INSPECTION, GENERAL SPECIFICATIONS FOR APPROVED PLANTS AND STANDARDS FOR GRADES OF DAIRY PRODUCTS 1 General....218 Surge tanks. If surge tanks are used for hot milk, and temperatures of product including...

  20. 7 CFR 1280.218 - Exporter.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE LAMB PROMOTION, RESEARCH, AND INFORMATION ORDER Lamb Promotion, Research, and Information Order Assessments § 1280.218 Exporter. Each person exporting live lambs shall remit to the Board an assessment on such lambs at the time of export at the...

  1. 50 CFR 218.184 - Requirements for monitoring and reporting.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... in § 218.180(c) is required to cooperate with the NMFS when monitoring the impacts of the activity on... procedures allow) if the specified activity identified in § 218.180(c) is thought to have resulted in the... § 218.181(b). (c) The Holder of the Letter of Authorization must conduct all monitoring and...

  2. 30 CFR 218.50 - Timing of payment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Timing of payment. 218.50 Section 218.50 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS AND INCENTIVES Oil and Gas, General § 218.50...

  3. 10 CFR 218.2 - Activation/Deactivation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false Activation/Deactivation. 218.2 Section 218.2 Energy DEPARTMENT OF ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION General Provisions § 218.2 Activation/Deactivation. (a) This rule shall take effect providing: (1) The International Energy Program has...

  4. 10 CFR 218.2 - Activation/Deactivation.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 3 2013-01-01 2013-01-01 false Activation/Deactivation. 218.2 Section 218.2 Energy DEPARTMENT OF ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION General Provisions § 218.2 Activation/Deactivation. (a) This rule shall take effect providing: (1) The International Energy Program has...

  5. 10 CFR 218.2 - Activation/Deactivation.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 3 2014-01-01 2014-01-01 false Activation/Deactivation. 218.2 Section 218.2 Energy DEPARTMENT OF ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION General Provisions § 218.2 Activation/Deactivation. (a) This rule shall take effect providing: (1) The International Energy Program has...

  6. 10 CFR 218.2 - Activation/Deactivation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Activation/Deactivation. 218.2 Section 218.2 Energy DEPARTMENT OF ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION General Provisions § 218.2 Activation/Deactivation. (a) This rule shall take effect providing: (1) The International Energy Program has...

  7. 10 CFR 218.2 - Activation/Deactivation.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 3 2012-01-01 2012-01-01 false Activation/Deactivation. 218.2 Section 218.2 Energy DEPARTMENT OF ENERGY OIL STANDBY MANDATORY INTERNATIONAL OIL ALLOCATION General Provisions § 218.2 Activation/Deactivation. (a) This rule shall take effect providing: (1) The International Energy Program has...

  8. 48 CFR 218.170 - Additional acquisition flexibilities.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Additional acquisition flexibilities. 218.170 Section 218.170 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS... Acquisition Flexibilities 218.170 Additional acquisition flexibilities. Additional acquisition...

  9. 48 CFR 218.170 - Additional acquisition flexibilities.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Additional acquisition flexibilities. 218.170 Section 218.170 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS... Acquisition Flexibilities 218.170 Additional acquisition flexibilities. Additional acquisition...

  10. 48 CFR 218.170 - Additional acquisition flexibilities.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Additional acquisition flexibilities. 218.170 Section 218.170 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS... Acquisition Flexibilities 218.170 Additional acquisition flexibilities. Additional acquisition...

  11. 48 CFR 218.170 - Additional acquisition flexibilities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Additional acquisition flexibilities. 218.170 Section 218.170 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS... Acquisition Flexibilities 218.170 Additional acquisition flexibilities. Additional acquisition...

  12. 48 CFR 218.170 - Additional acquisition flexibilities.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Additional acquisition flexibilities. 218.170 Section 218.170 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS... Acquisition Flexibilities 218.170 Additional acquisition flexibilities. Additional acquisition...

  13. 49 CFR 218.30 - Remotely controlled switches.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Remotely controlled switches. 218.30 Section 218....30 Remotely controlled switches. (a) After the operator of the remotely controlled switches has received the notification required by § 218.27(c), he must line each remotely controlled switch...

  14. 49 CFR 218.30 - Remotely controlled switches.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Remotely controlled switches. 218.30 Section 218....30 Remotely controlled switches. (a) After the operator of the remotely controlled switches has received the notification required by § 218.27(c), he must line each remotely controlled switch...

  15. 49 CFR 218.30 - Remotely controlled switches.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Remotely controlled switches. 218.30 Section 218....30 Remotely controlled switches. (a) After the operator of the remotely controlled switches has received the notification required by § 218.27(c), he must line each remotely controlled switch...

  16. 18 CFR 2.18 - Phased electric rate increase filings.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Phased electric rate increase filings. 2.18 Section 2.18 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... Policy and Interpretations Under the Federal Power Act § 2.18 Phased electric rate increase filings....

  17. 18 CFR 2.18 - Phased electric rate increase filings.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Phased electric rate increase filings. 2.18 Section 2.18 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... Policy and Interpretations Under the Federal Power Act § 2.18 Phased electric rate increase filings....

  18. 18 CFR 2.18 - Phased electric rate increase filings.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Phased electric rate increase filings. 2.18 Section 2.18 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... Policy and Interpretations Under the Federal Power Act § 2.18 Phased electric rate increase filings....

  19. 18 CFR 2.18 - Phased electric rate increase filings.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Phased electric rate increase filings. 2.18 Section 2.18 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... Policy and Interpretations Under the Federal Power Act § 2.18 Phased electric rate increase filings....

  20. 18 CFR 2.18 - Phased electric rate increase filings.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Phased electric rate increase filings. 2.18 Section 2.18 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... Policy and Interpretations Under the Federal Power Act § 2.18 Phased electric rate increase filings....

  1. 14 CFR 21.8 - Approval of articles.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Approval of articles. 21.8 Section 21.8 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT CERTIFICATION PROCEDURES FOR PRODUCTS AND PARTS General § 21.8 Approval of articles. If an article is required to...

  2. 14 CFR 21.8 - Approval of articles.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Approval of articles. 21.8 Section 21.8 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT CERTIFICATION PROCEDURES FOR PRODUCTS AND PARTS General § 21.8 Approval of articles. If an article is required to...

  3. 14 CFR 21.8 - Approval of articles.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Approval of articles. 21.8 Section 21.8 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT CERTIFICATION PROCEDURES FOR PRODUCTS AND PARTS General § 21.8 Approval of articles. If an article is required to...

  4. 14 CFR 21.8 - Approval of articles.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Approval of articles. 21.8 Section 21.8 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT CERTIFICATION PROCEDURES FOR PRODUCTS AND PARTS General § 21.8 Approval of articles. If an article is required to...

  5. 14 CFR 21.8 - Approval of articles.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Approval of articles. 21.8 Section 21.8 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT CERTIFICATION PROCEDURES FOR PRODUCTS AND PARTS General § 21.8 Approval of articles. If an article is required to...

  6. 49 CFR 384.218 - Second serious traffic violation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 5 2013-10-01 2013-10-01 false Second serious traffic violation. 384.218 Section 384.218 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER... § 384.218 Second serious traffic violation. The State must disqualify from operating a CMV for a...

  7. 49 CFR 384.218 - Second serious traffic violation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Second serious traffic violation. 384.218 Section 384.218 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER... § 384.218 Second serious traffic violation. The State must disqualify from operating a CMV for a...

  8. 49 CFR 384.218 - Second serious traffic violation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 5 2012-10-01 2012-10-01 false Second serious traffic violation. 384.218 Section 384.218 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER... § 384.218 Second serious traffic violation. The State must disqualify from operating a CMV for a...

  9. 49 CFR 384.218 - Second serious traffic violation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 5 2011-10-01 2011-10-01 false Second serious traffic violation. 384.218 Section 384.218 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER... § 384.218 Second serious traffic violation. The State must disqualify from operating a CMV for a...

  10. 49 CFR 384.218 - Second serious traffic violation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 5 2014-10-01 2014-10-01 false Second serious traffic violation. 384.218 Section 384.218 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER... § 384.218 Second serious traffic violation. The State must disqualify from operating a CMV for a...

  11. 20 CFR 218.15 - When a parent annuity begins.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true When a parent annuity begins. 218.15 Section 218.15 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD RETIREMENT ACT ANNUITY BEGINNING AND ENDING DATES When an Annuity Begins § 218.15 When a parent annuity begins. A...

  12. 20 CFR 218.15 - When a parent annuity begins.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false When a parent annuity begins. 218.15 Section 218.15 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD RETIREMENT ACT ANNUITY BEGINNING AND ENDING DATES When an Annuity Begins § 218.15 When a parent annuity begins. A...

  13. 20 CFR 218.42 - When a parent annuity ends.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true When a parent annuity ends. 218.42 Section 218... ANNUITY BEGINNING AND ENDING DATES When an Annuity Ends § 218.42 When a parent annuity ends. (a) Tier I. The tier I benefit of a parent annuity ends with the earliest of the last day of the month before...

  14. 20 CFR 218.15 - When a parent annuity begins.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true When a parent annuity begins. 218.15 Section 218.15 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD RETIREMENT ACT ANNUITY BEGINNING AND ENDING DATES When an Annuity Begins § 218.15 When a parent annuity begins. A...

  15. 20 CFR 218.15 - When a parent annuity begins.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false When a parent annuity begins. 218.15 Section 218.15 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD RETIREMENT ACT ANNUITY BEGINNING AND ENDING DATES When an Annuity Begins § 218.15 When a parent annuity begins. A...

  16. 20 CFR 218.42 - When a parent annuity ends.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true When a parent annuity ends. 218.42 Section 218... ANNUITY BEGINNING AND ENDING DATES When an Annuity Ends § 218.42 When a parent annuity ends. (a) Tier I. The tier I benefit of a parent annuity ends with the earliest of the last day of the month before...

  17. 20 CFR 218.15 - When a parent annuity begins.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false When a parent annuity begins. 218.15 Section 218.15 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD RETIREMENT ACT ANNUITY BEGINNING AND ENDING DATES When an Annuity Begins § 218.15 When a parent annuity begins. A...

  18. 49 CFR 218.109 - Hand-operated fixed derails.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Hand-operated fixed derails. 218.109 Section 218.109 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... Derails § 218.109 Hand-operated fixed derails. (a)(1) Each railroad shall adopt and comply with...

  19. 49 CFR 218.109 - Hand-operated fixed derails.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Hand-operated fixed derails. 218.109 Section 218.109 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... Derails § 218.109 Hand-operated fixed derails. (a)(1) Each railroad shall adopt and comply with...

  20. 49 CFR 218.109 - Hand-operated fixed derails.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Hand-operated fixed derails. 218.109 Section 218.109 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... Derails § 218.109 Hand-operated fixed derails. (a)(1) Each railroad shall adopt and comply with...

  1. 49 CFR 218.30 - Remotely controlled switches.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Remotely controlled switches. 218.30 Section 218....30 Remotely controlled switches. (a) After the operator of the remotely controlled switches has received the notification required by § 218.27(c), he must line each remotely controlled switch...

  2. 49 CFR 218.30 - Remotely controlled switches.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Remotely controlled switches. 218.30 Section 218....30 Remotely controlled switches. (a) After the operator of the remotely controlled switches has received the notification required by § 218.27(c), he must line each remotely controlled switch...

  3. 40 CFR 86.218-94 - Dynamometer calibration.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 18 2010-07-01 2010-07-01 false Dynamometer calibration. 86.218-94 Section 86.218-94 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS...-Duty Passenger Vehicles; Cold Temperature Test Procedures § 86.218-94 Dynamometer calibration....

  4. 22 CFR 218.23 - Self-evaluation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... written self-evaluation of its compliance under the act within 18 months of the effective date of these... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Self-evaluation. 218.23 Section 218.23 Foreign... ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Duties of Agency Recipients § 218.23 Self-evaluation....

  5. 49 CFR 218.80 - Movement of occupied camp cars.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Movement of occupied camp cars. 218.80 Section 218... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Protection of Occupied Camp Cars § 218.80 Movement of occupied camp cars. Occupied cars may not be humped or flat switched unless coupled...

  6. 49 CFR 218.80 - Movement of occupied camp cars.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Movement of occupied camp cars. 218.80 Section 218... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Protection of Occupied Camp Cars § 218.80 Movement of occupied camp cars. Occupied cars may not be humped or flat switched unless coupled...

  7. 49 CFR 218.80 - Movement of occupied camp cars.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Movement of occupied camp cars. 218.80 Section 218... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Protection of Occupied Camp Cars § 218.80 Movement of occupied camp cars. Occupied cars may not be humped or flat switched unless coupled...

  8. 49 CFR 218.80 - Movement of occupied camp cars.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Movement of occupied camp cars. 218.80 Section 218... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Protection of Occupied Camp Cars § 218.80 Movement of occupied camp cars. Occupied cars may not be humped or flat switched unless coupled...

  9. 49 CFR 218.80 - Movement of occupied camp cars.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Movement of occupied camp cars. 218.80 Section 218... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Protection of Occupied Camp Cars § 218.80 Movement of occupied camp cars. Occupied cars may not be humped or flat switched unless coupled...

  10. 20 CFR 218.41 - When a child annuity ends.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true When a child annuity ends. 218.41 Section 218... ANNUITY BEGINNING AND ENDING DATES When an Annuity Ends § 218.41 When a child annuity ends. A child annuity ends with the earliest of— (a) The last day of the month before the month in which the...

  11. 20 CFR 218.41 - When a child annuity ends.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true When a child annuity ends. 218.41 Section 218... ANNUITY BEGINNING AND ENDING DATES When an Annuity Ends § 218.41 When a child annuity ends. A child annuity ends with the earliest of— (a) The last day of the month before the month in which the...

  12. 20 CFR 218.41 - When a child annuity ends.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false When a child annuity ends. 218.41 Section 218... ANNUITY BEGINNING AND ENDING DATES When an Annuity Ends § 218.41 When a child annuity ends. A child annuity ends with the earliest of— (a) The last day of the month before the month in which the...

  13. 20 CFR 218.41 - When a child annuity ends.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false When a child annuity ends. 218.41 Section 218... ANNUITY BEGINNING AND ENDING DATES When an Annuity Ends § 218.41 When a child annuity ends. A child annuity ends with the earliest of— (a) The last day of the month before the month in which the...

  14. 49 CFR 218.73 - Warning signal display.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Warning signal display. 218.73 Section 218.73 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Protection of Occupied Camp Cars § 218.73...

  15. 49 CFR 218.71 - Purpose and scope.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Purpose and scope. 218.71 Section 218.71 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Protection of Occupied Camp Cars § 218.71...

  16. 5 CFR 179.218 - Additional administrative collection action.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Additional administrative collection action. 179.218 Section 179.218 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS CLAIMS COLLECTION STANDARDS Salary Offset § 179.218 Additional administrative collection...

  17. Production of [211At]-Astatinated Radiopharmaceuticals and Applications in Targeted α-Particle Therapy

    PubMed Central

    Guérard, François; Gestin, Jean-François

    2013-01-01

    Abstract 211At is a promising radionuclide for α-particle therapy of cancers. Its physical characteristics make this radionuclide particularly interesting to consider when bound to cancer-targeting biomolecules for the treatment of microscopic tumors. 211At is produced by cyclotron irradiation of 209Bi with α-particles accelerated at ∼28 MeV and can be obtained in high radionuclidic purity after isolation from the target. Its chemistry resembles iodine, but there is also a tendency to behave as a metalloid. However, the chemical behavior of astatine has not yet been clearly established, primarily due to the lack of any stable isotopes of this element, which precludes the use of conventional analytical techniques for its characterization. There are also only a limited number of research centers that have been able to produce this element in sufficient amounts to carry out extensive investigations. Despite these difficulties, chemical reactions typically used with iodine can be performed, and a number of biomolecules of interest have been labeled with 211At. However, most of these compounds exhibit unacceptable instability in vivo due to the weakness of the astatine–biomolecule bond. Nonetheless, several compounds have shown high potential for the treatment of cancers in vitro and in several animal models, thus providing a promising basis that has allowed initiation of the first two clinical studies. PMID:23075373

  18. Unexpected Behavior of the Heaviest Halogen Astatine in the Nucleophilic Substitution of Aryliodonium Salts.

    PubMed

    Guérard, François; Lee, Yong-Sok; Baidoo, Kwamena; Gestin, Jean-François; Brechbiel, Martin W

    2016-08-22

    Aryliodonium salts have become precursors of choice for the synthesis of (18) F-labeled tracers for nuclear imaging. However, little is known on the reactivity of these compounds with heavy halides, that is, radioiodide and astatide, at the radiotracer scale. In the first comparative study of radiohalogenation of aryliodonium salts with (125) I(-) and (211) At(-) , initial experiments on a model compound highlight the higher reactivity of astatide compared to iodide, which could not be anticipated from the trends previously observed within the halogen series. Kinetic studies indicate a significant difference in activation energy (Ea =23.5 and 17.1 kcal mol(-1) with (125) I(-) and (211) At(-) , respectively). Quantum chemical calculations suggest that astatination occurs via the monomeric form of an iodonium complex whereas iodination occurs via a heterodimeric iodonium intermediate. The good to excellent regioselectivity of halogenation and high yields achieved with diversely substituted aryliodonium salts indicate that this class of compounds is a promising alternative to the stannane chemistry currently used for heavy radiohalogen labeling of tracers in nuclear medicine.

  19. Half-life of /sup 218/Po

    SciTech Connect

    Potapov, V.G.; Soloshenkov, P.S.

    1986-10-01

    The decay of Po 218 is accompanied by the emission of 6.00-MeV alpha particles. The most suitable method for studying it is the alphaspectrometric method. To generate radon, the source for RaA, the authors used a preparation of Ra 226 with a high degree of purity. Targets were prepared for measuring the half-life on a radon setup. Approximately 30 sec after holding in a radon atmosphere the target was placed with the polonium deposited on it into a vacuum chamber. It was noted that the intensity of the peak at 6.70 MeV decreases at the same rate as the decay of Po 218, and the ratio of the intensities of their peaks was equal to 0.037 +/- 0.007%. The spectra (alpha was analyzed on an LP-4900 analyzer. The values of the half-life that were obtained are in good agreement with the values obtained previously.

  20. The atmospheric chemistry of Po-218

    SciTech Connect

    Hopke, P.K.

    1990-09-30

    The chemical and physical properties of {sup 218}Po immediately following its formation from {sup 222}Rn decay are important in determining its behavior in indoor atmospheres and plays a major part in determining its potential health effects. In 88% of the decays, a singly charged positive ion of {sup 218}Po is obtained at the end of its recoil path. The neutralization rates for Po-218 by the small ion recombination, electron transfer or electron scavenging mechanisms were previously reported. We have measured the small ion recombination rate in high purity gases to determine the negative small ion production rate as a function of the ionization potential of the gas. Our previous studies have also shown that radiolysis of water vapor by the recoiling Po ion produces high local concentrations of hydroxyl ({center dot}OH) radicals. These radicals can lead to oxidation of reactive trace gases and the neutral polonium molecule can become incorporated in ultrafine particles formed by the nucleation of low vapor pressure compounds produced by this radical oxidation process. The hydroxyl radical production rate and the production of particles are currently being studied. 12 refs., 1 fig.

  1. Ionization potentials, electron affinities, resonance excitation energies, oscillator strengths, and ionic radii of element Uus (Z = 117) and astatine.

    PubMed

    Chang, Zhiwei; Li, Jiguang; Dong, Chenzhong

    2010-12-30

    Multiconfiguration Dirac-Fock (MCDF) method was employed to calculate the first five ionization potentials, electron affinities, resonance excitation energies, oscillator strengths, and radii for the element Uus and its homologue At. Main valence correlation effects were taken into account. The Breit interaction and QED effects were also estimated. The uncertainties of calculated IPs, EAs, and IR for Uus and At were reduced through an extrapolation procedure. The good consistency with available experimental and other theoretical values demonstrates the validity of the present results. These theoretical data therefore can be used to predict some unknown physicochemical properties of element Uus, Astatine, and their compounds.

  2. ASTATINE-211 RADIOCHEMISTRY: THE DEVELOPMENT OF METHODOLOGIES FOR HIGH ACTIVITY LEVEL RADIOSYNTHESIS

    SciTech Connect

    MICHAEL R. ZALUTSKY

    2012-08-08

    Targeted radionuclide therapy is emerging as a viable approach for cancer treatment because of its potential for delivering curative doses of radiation to malignant cell populations while sparing normal tissues. Alpha particles such as those emitted by 211At are particularly attractive for this purpose because of their short path length in tissue and high energy, making them highly effective in killing cancer cells. The current impact of targeted radiotherapy in the clinical domain remains limited despite the fact that in many cases, potentially useful molecular targets and labeled compounds have already been identified. Unfortunately, putting these concepts into practice has been impeded by limitations in radiochemistry methodologies. A critical problem is that the synthesis of therapeutic radiopharmaceuticals provides additional challenges in comparison to diagnostic reagents because of the need to perform radio-synthesis at high levels of radioactivity. This is particularly important for {alpha}-particle emitters such as 211At because they deposit large amounts of energy in a highly focal manner. The overall objective of this project is to develop convenient and reproducible radiochemical methodologies for the radiohalogenation of molecules with the {alpha}-particle emitter 211At at the radioactivity levels needed for clinical studies. Our goal is to address two problems in astatine radiochemistry: First, a well known characteristic of 211At chemistry is that yields for electrophilic astatination reactions decline as the time interval after radionuclide isolation from the cyclotron target increases. This is a critical problem that must be addressed if cyclotrons are to be able to efficiently supply 211At to remote users. And second, when the preparation of high levels of 211At-labeled compounds is attempted, the radiochemical yields can be considerably lower than those encountered at tracer dose. For these reasons, clinical evaluation of promising 211At

  3. Reagents for astatination of biomolecules. 3. Comparison of closo-decaborate(2-) and closo-dodecaborate(2-) moieties as reactive groups for labeling with astatine-211.

    PubMed

    Wilbur, D Scott; Chyan, Ming-Kuan; Hamlin, Donald K; Perry, Matthew A

    2009-03-18

    In vivo deastatination has been a major problem in the development of reagents for therapeutic applications of the alpha-particle emitting radionuclide (211)At. Our prior studies demonstrated that the use of a closo-decaborate(2-) ([closo-B(10)H(9)R](2-)) moiety for (211)At labeling of biomolecules provides conjugates that are stable to in vivo deastatination. In this investigation, the closo-decaborate(2-) moiety was compared with the structurally similar closo-dodecaborate(2-) ([closo-B(12)H(11)R](2-)) to determine if one has more favorable properties than the other for use in pendant groups as (211)At labeling molecules. To determine the differences, two sets of structurally identical molecules, with the exception that they contained either a closo-decaborate(2-) or a closo-dodecaborate(2-) moiety, were compared with regard to their synthesis, radiohalogenation, stability to in vivo deastatination and tissue distribution. Quite different rates of reaction were noted in the synthetic steps for the two closo-borate(2-) moieties, but ultimately the yields were similar, making these differences of little importance. Differences in radiohalogenation rates were also noted between the two closo-borate(2-) moieties, with the more electrophilic closo-decaborate(2-) reacting more rapidly. This resulted in somewhat higher yields of astatinated closo-decaborate(2-) derivatives (84% vs 53%), but both cage moieties gave good radioiodination yields (e.g., 79-96%). Importantly, both closo-borate(2-) cage moieties were shown to have high stability to in vivo deastatination. The largest differences between pairs of compounds containing the structurally similar boron cage moieties were in their in vivo tissue distributions. For example, [Et(3)NH](2)B(12)H(10)I-CONHpropyl, [(125)I]2b had high concentrations in kidney (1 h, 19.8%ID/g; 4 h, 26.5%ID/g), whereas [Et(3)NH](2)B(10)H(8)I-CONHpropyl, [(125)I]1e had much lower concentrations in kidney (1 h, 6.6%ID/g; 4 h, 0.27%ID

  4. Therapeutic Efficacy of Astatine-211-Labeled Trastuzumab on Radioresistant SKOV-3 Tumors in Nude Mice

    SciTech Connect

    Palm, Stig Baeck, Tom; Claesson, Ingela; Danielsson, Anna; Elgqvist, Joergen; Frost, Sofia; Hultborn, Ragnar; Jensen, Holger; Lindegren, Sture; Jacobsson, Lars

    2007-10-01

    Purpose: To investigate the potential use of astatine-211 ({sup 211}At)-labeled trastuzumab for the treatment of HER-2-positive, radioresistant ovarian carcinoma. Methods and Materials: Four-week-old nude mice were inoculated intraperitoneally with 5 . 10{sup 6} SKOV-3 cells in 0.4 mL saline on Day 0. The endpoint was the total tumor weight in each mouse on Day 63. Three experiments were performed in which the response to single-dose and fractionated treatment with unlabeled and {sup 211}At-labeled antibody was evaluated. Results: Experiment 1 showed, for the same total amount of trastuzumab, a dose-response relationship between {sup 211}At activity (0-400 kBq on Day 7) and therapeutic efficacy (p = 0.001). The effect of varying the amount of unlabeled trastuzumab was studied in Experiment 2. All mice, except for the controls, received 400 kBq {sup 211}At-trastuzumab, and different groups received 5, 50, or 500 {mu}g trastuzumab on Day 7. The increase from 5 to 50 {mu}g trastuzumab reduced the tumors by 78% in weight. No tumors were present in mice given 500 {mu}g trastuzumab. In Experiment 3, the effect of a fractionated treatment regimen was studied. Mice that received 100 kBq {sup 211}At-trastuzumab on Days 7 and 8 had a 42% smaller tumor burden than did controls. Groups of mice injected with 200 + 100 kBq on Days 7 and 21 and mice injected with 100 kBq on Days 7, 8, and 21 both had 24% less tumor weight than the corresponding controls. Conclusion: The combination of 500 {mu}g trastuzumab and 400 kBq {sup 211}At-trastuzumab had the greatest effect, with complete eradication of the tumors in this nude mouse model.

  5. Factor Analysis Applied the VFY-218 RCS Data

    NASA Technical Reports Server (NTRS)

    Woo, Alex; Chancellor, Marisa K. (Technical Monitor)

    1997-01-01

    Present statistical factor analysis of computer simulations and measurement data for the VFY-218 configuration. Factor analysis try to quantify the statistical grouping of measurements and simulations.

  6. Kinetics of neutralization of Po-218

    SciTech Connect

    Chu, K.D.

    1987-01-01

    In a well-defined experimental system the neutralization of polonium-218 ions was investigated as a function of the physical and chemical properties of the controlled composition atmosphere. The mobilities of Po/sup +/ and PoO/sub 2//sup +/ are determined by combining experimental results with a computer model of the system. Three neutralization mechanisms were individually studied. The small ion recombination rate has been found to be proportional to the square root of radon concentration. The electron scavenging mechanism is responsible for the neutralization of Po/sup +/ in NO/sub 2/ or H/sub 2/O in nitrogen. When PoO/sub 2//sup +/ is formed, the electron transfer mechanism dominates the neutralization process. The electron is transferred to PoO/sub 2//sup +/ from molecules with lower ionization potentials. The ionization potential of PoO/sub 2//sup +/ is also determined to be 10.44 +/- 0.05 eV.

  7. 30 CFR 218.302 - Late payment or underpayment charges.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Late payment or underpayment charges. 218.302 Section 218.302 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS AND INCENTIVES Geothermal...

  8. 30 CFR 218.55 - Interest payments to Indians.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Interest payments to Indians. 218.55 Section 218.55 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS AND INCENTIVES Oil and Gas,...

  9. 30 CFR 218.201 - Method of payment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Method of payment. 218.201 Section 218.201 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS AND INCENTIVES Solid Minerals-General §...

  10. 30 CFR 218.301 - Method of payment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Method of payment. 218.301 Section 218.301 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS AND INCENTIVES Geothermal Resources §...

  11. 30 CFR 218.202 - Late payment or underpayment charges.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Late payment or underpayment charges. 218.202 Section 218.202 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS AND INCENTIVES Solid...

  12. 30 CFR 218.102 - Late payment or underpayment charges.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Late payment or underpayment charges. 218.102 Section 218.102 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS AND INCENTIVES Oil and Gas,...

  13. 30 CFR 218.100 - Royalty and rental payments.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Royalty and rental payments. 218.100 Section 218.100 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS AND INCENTIVES Oil and Gas,...

  14. 30 CFR 218.103 - Payments to States.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Payments to States. 218.103 Section 218.103 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS AND INCENTIVES Oil and Gas, Onshore §...

  15. 40 CFR 761.218 - Certificate of disposal.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Section 761.218 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.218 Certificate of disposal. (a) For each shipment of manifested PCB waste that the owner or operator of a disposal facility accepts by signing the manifest,...

  16. 40 CFR 761.218 - Certificate of disposal.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Section 761.218 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.218 Certificate of disposal. (a) For each shipment of manifested PCB waste that the owner or operator of a disposal facility accepts by signing the manifest,...

  17. 40 CFR 761.218 - Certificate of disposal.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Section 761.218 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.218 Certificate of disposal. (a) For each shipment of manifested PCB waste that the owner or operator of a disposal facility accepts by signing the manifest,...

  18. 40 CFR 761.218 - Certificate of disposal.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Section 761.218 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.218 Certificate of disposal. (a) For each shipment of manifested PCB waste that the owner or operator of a disposal facility accepts by signing the manifest,...

  19. 40 CFR 761.218 - Certificate of disposal.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Section 761.218 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES... PROHIBITIONS PCB Waste Disposal Records and Reports § 761.218 Certificate of disposal. (a) For each shipment of manifested PCB waste that the owner or operator of a disposal facility accepts by signing the manifest,...

  20. 28 CFR 115.218 - Upgrades to facilities and technologies.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Upgrades to facilities and technologies. 115.218 Section 115.218 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE... residents from sexual abuse. (b) When installing or updating a video monitoring system,...

  1. 28 CFR 115.218 - Upgrades to facilities and technologies.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Upgrades to facilities and technologies. 115.218 Section 115.218 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE... residents from sexual abuse. (b) When installing or updating a video monitoring system,...

  2. 28 CFR 115.218 - Upgrades to facilities and technologies.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Upgrades to facilities and technologies. 115.218 Section 115.218 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE... residents from sexual abuse. (b) When installing or updating a video monitoring system,...

  3. 41 CFR 101-29.218 - Voluntary standards.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Voluntary standards. 101-29.218 Section 101-29.218 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS SUPPLY AND PROCUREMENT 29-FEDERAL...

  4. 49 CFR 218.59 - Responsibilities of railroads.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Responsibilities of railroads. 218.59 Section 218.59 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Prohibition Against Tampering...

  5. 49 CFR 218.59 - Responsibilities of railroads.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Responsibilities of railroads. 218.59 Section 218.59 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Prohibition Against Tampering...

  6. 49 CFR 218.59 - Responsibilities of railroads.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Responsibilities of railroads. 218.59 Section 218.59 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Prohibition Against Tampering...

  7. 49 CFR 218.95 - Instruction, training, and examination.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Instruction, training, and examination. 218.95 Section 218.95 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Handling Equipment, Switches, and...

  8. 49 CFR 218.99 - Shoving or pushing movements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Shoving or pushing movements. 218.99 Section 218.99 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Handling Equipment, Switches, and...

  9. 49 CFR 218.99 - Shoving or pushing movements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Shoving or pushing movements. 218.99 Section 218.99 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Handling Equipment, Switches, and...

  10. 49 CFR 218.77 - Remotely controlled switches.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Remotely controlled switches. 218.77 Section 218....77 Remotely controlled switches. (a) After the operator of the remotely controlled switch is notified that a camp car is to be placed on a particular track, he shall line such switch against movement...

  11. 49 CFR 218.99 - Shoving or pushing movements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Shoving or pushing movements. 218.99 Section 218.99 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Handling Equipment, Switches, and...

  12. 49 CFR 218.95 - Instruction, training, and examination.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Instruction, training, and examination. 218.95 Section 218.95 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Handling Equipment, Switches, and...

  13. 49 CFR 218.95 - Instruction, training, and examination.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Instruction, training, and examination. 218.95 Section 218.95 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Handling Equipment, Switches, and...

  14. 29 CFR 825.218 - Substantial and grievous economic injury.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Substantial and grievous economic injury. 825.218 Section... Medical Leave Act § 825.218 Substantial and grievous economic injury. (a) In order to deny restoration to... cause “substantial and grievous economic injury” to the operations of the employer, not whether...

  15. 49 CFR 218.59 - Responsibilities of railroads.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Responsibilities of railroads. 218.59 Section 218.59 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Prohibition Against Tampering...

  16. 49 CFR 218.59 - Responsibilities of railroads.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Responsibilities of railroads. 218.59 Section 218.59 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Prohibition Against Tampering...

  17. 48 CFR 53.217-53.218 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false 53.217-53.218 Section 53.217-53.218 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms...

  18. 29 CFR 825.218 - Substantial and grievous economic injury.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 3 2013-07-01 2013-07-01 false Substantial and grievous economic injury. 825.218 Section... Medical Leave Act § 825.218 Substantial and grievous economic injury. (a) In order to deny restoration to... cause substantial and grievous economic injury to the operations of the employer, not whether...

  19. 29 CFR 825.218 - Substantial and grievous economic injury.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 3 2012-07-01 2012-07-01 false Substantial and grievous economic injury. 825.218 Section... Medical Leave Act § 825.218 Substantial and grievous economic injury. (a) In order to deny restoration to... cause “substantial and grievous economic injury” to the operations of the employer, not whether...

  20. 29 CFR 825.218 - Substantial and grievous economic injury.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Substantial and grievous economic injury. 825.218 Section... Medical Leave Act § 825.218 Substantial and grievous economic injury. (a) In order to deny restoration to... cause “substantial and grievous economic injury” to the operations of the employer, not whether...

  1. 20 CFR 218.42 - When a parent annuity ends.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false When a parent annuity ends. 218.42 Section... ANNUITY BEGINNING AND ENDING DATES When an Annuity Ends § 218.42 When a parent annuity ends. (a) Tier I. The tier I benefit of a parent annuity ends with the earliest of the last day of the month before...

  2. 20 CFR 218.42 - When a parent annuity ends.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false When a parent annuity ends. 218.42 Section... ANNUITY BEGINNING AND ENDING DATES When an Annuity Ends § 218.42 When a parent annuity ends. (a) Tier I. The tier I benefit of a parent annuity ends with the earliest of the last day of the month before...

  3. 20 CFR 218.42 - When a parent annuity ends.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false When a parent annuity ends. 218.42 Section... ANNUITY BEGINNING AND ENDING DATES When an Annuity Ends § 218.42 When a parent annuity ends. (a) Tier I. The tier I benefit of a parent annuity ends with the earliest of the last day of the month before...

  4. 24 CFR 972.218 - Conversion assessment components.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Conversion assessment components. 972.218 Section 972.218 Housing and Urban Development Regulations Relating to Housing and Urban... URBAN DEVELOPMENT CONVERSION OF PUBLIC HOUSING TO TENANT-BASED ASSISTANCE Voluntary Conversion of...

  5. 49 CFR 218.99 - Shoving or pushing movements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Shoving or pushing movements. 218.99 Section 218.99 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Handling Equipment, Switches, and...

  6. 49 CFR 218.99 - Shoving or pushing movements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Shoving or pushing movements. 218.99 Section 218.99 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Handling Equipment, Switches, and...

  7. 49 CFR 218.95 - Instruction, training, and examination.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Instruction, training, and examination. 218.95 Section 218.95 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Handling Equipment, Switches, and...

  8. 49 CFR 218.95 - Instruction, training, and examination.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Instruction, training, and examination. 218.95 Section 218.95 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Handling Equipment, Switches, and...

  9. 49 CFR 218.109 - Hand-operated fixed derails.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Hand-operated fixed derails. 218.109 Section 218.109 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Handling Equipment, Switches, and...

  10. 49 CFR 218.109 - Hand-operated fixed derails.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Hand-operated fixed derails. 218.109 Section 218.109 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Handling Equipment, Switches, and...

  11. 49 CFR 218.77 - Remotely controlled switches.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Remotely controlled switches. 218.77 Section 218....77 Remotely controlled switches. (a) After the operator of the remotely controlled switch is notified that a camp car is to be placed on a particular track, he shall line such switch against movement...

  12. 49 CFR 218.77 - Remotely controlled switches.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Remotely controlled switches. 218.77 Section 218....77 Remotely controlled switches. (a) After the operator of the remotely controlled switch is notified that a camp car is to be placed on a particular track, he shall line such switch against movement...

  13. 49 CFR 218.79 - Alternative methods of protection.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 218.79 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Protection of Occupied Camp Cars § 218... cars are on track other than main track: (1) A warning signal must be displayed at or near each...

  14. 49 CFR 218.79 - Alternative methods of protection.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 218.79 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Protection of Occupied Camp Cars § 218... cars are on track other than main track: (1) A warning signal must be displayed at or near each...

  15. 49 CFR 173.218 - Fish meal or fish scrap.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 2 2011-10-01 2011-10-01 false Fish meal or fish scrap. 173.218 Section 173.218... Fish meal or fish scrap. (a) Except as provided in Column (7) of the HMT in § 172.101 of this subchapter, fish meal or fish scrap, containing at least 6%, but not more than 12% water, is authorized...

  16. 50 CFR 218.112 - Permissible methods of taking.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... MAMMALS Taking and Importing Marine Mammals; U.S. Navy's Northwest Training Range Complex (NWTRC) § 218... and 218.117 of this chapter, the Holder of the Letter of Authorization (hereinafter “Navy”) may... average of 119274 annually). (ii) Pinnipeds: (A) Northern elephant seal (Mirounga angustirostris)—1890...

  17. 50 CFR 218.112 - Permissible methods of taking.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... MAMMALS Taking and Importing Marine Mammals; U.S. Navy's Northwest Training Range Complex (NWTRC) § 218... and 218.117 of this chapter, the Holder of the Letter of Authorization (hereinafter “Navy”) may... average of 119274 annually). (ii) Pinnipeds: (A) Northern elephant seal (Mirounga angustirostris)—1890...

  18. 50 CFR 218.112 - Permissible methods of taking.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... MAMMALS Taking and Importing Marine Mammals; U.S. Navy's Northwest Training Range Complex (NWTRC) § 218... and 218.117 of this chapter, the Holder of the Letter of Authorization (hereinafter “Navy”) may... average of 119274 annually). (ii) Pinnipeds: (A) Northern elephant seal (Mirounga angustirostris)—1890...

  19. 50 CFR 218.112 - Permissible methods of taking.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... MAMMALS Taking and Importing Marine Mammals; U.S. Navy's Northwest Training Range Complex (NWTRC) § 218... and 218.117 of this chapter, the Holder of the Letter of Authorization (hereinafter “Navy”) may... average of 119274 annually). (ii) Pinnipeds: (A) Northern elephant seal (Mirounga angustirostris)—1890...

  20. 50 CFR 218.115 - Requirements for monitoring and reporting.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 10 2013-10-01 2013-10-01 false Requirements for monitoring and reporting. 218.115 Section 218.115 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND... dead), location, time of first discovery, observed behaviors (if alive), and photo or video...

  1. 50 CFR 218.184 - Requirements for monitoring and reporting.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 10 2013-10-01 2013-10-01 false Requirements for monitoring and reporting. 218.184 Section 218.184 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND..., observed behaviors (if alive), and photo or video (if available). (e) If there is clear evidence that...

  2. 50 CFR 218.115 - Requirements for monitoring and reporting.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 10 2014-10-01 2014-10-01 false Requirements for monitoring and reporting. 218.115 Section 218.115 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND... dead), location, time of first discovery, observed behaviors (if alive), and photo or video...

  3. 49 CFR 218.73 - Warning signal display.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Warning signal display. 218.73 Section 218.73... signal display. (a) Warning signals, i.e., a white disk with the words “Occupied Camp Car” in black lettering during daylight hours and an illuminated white signal at night, displayed in accordance with §...

  4. 49 CFR 218.73 - Warning signal display.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Warning signal display. 218.73 Section 218.73... signal display. (a) Warning signals, i.e., a white disk with the words “Occupied Camp Car” in black lettering during daylight hours and an illuminated white signal at night, displayed in accordance with §...

  5. 49 CFR 218.73 - Warning signal display.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Warning signal display. 218.73 Section 218.73... signal display. (a) Warning signals, i.e., a white disk with the words “Occupied Camp Car” in black lettering during daylight hours and an illuminated white signal at night, displayed in accordance with §...

  6. 49 CFR 218.73 - Warning signal display.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Warning signal display. 218.73 Section 218.73... signal display. (a) Warning signals, i.e., a white disk with the words “Occupied Camp Car” in black lettering during daylight hours and an illuminated white signal at night, displayed in accordance with §...

  7. 20 CFR 218.14 - When a child annuity begins.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true When a child annuity begins. 218.14 Section... ANNUITY BEGINNING AND ENDING DATES When an Annuity Begins § 218.14 When a child annuity begins. (a) A child annuity begins on the later of either the date chosen by the applicant or the earliest...

  8. 20 CFR 218.14 - When a child annuity begins.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false When a child annuity begins. 218.14 Section... ANNUITY BEGINNING AND ENDING DATES When an Annuity Begins § 218.14 When a child annuity begins. (a) A child annuity begins on the later of either the date chosen by the applicant or the earliest...

  9. 20 CFR 218.14 - When a child annuity begins.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true When a child annuity begins. 218.14 Section... ANNUITY BEGINNING AND ENDING DATES When an Annuity Begins § 218.14 When a child annuity begins. (a) A child annuity begins on the later of either the date chosen by the applicant or the earliest...

  10. 20 CFR 218.14 - When a child annuity begins.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false When a child annuity begins. 218.14 Section... ANNUITY BEGINNING AND ENDING DATES When an Annuity Begins § 218.14 When a child annuity begins. (a) A child annuity begins on the later of either the date chosen by the applicant or the earliest...

  11. 49 CFR 218.79 - Alternative methods of protection.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Alternative methods of protection. 218.79 Section 218.79 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Protection of Occupied Camp Cars §...

  12. 50 CFR 218.184 - Requirements for monitoring and reporting.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    .... 218.184 Section 218.184 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND..., the monitoring activities summarized below. (1) Visual Surveys—Vessel, Aerial and Shore-based: The... limited to: (A) Location of sighting; (B) Species (or to the lowest taxa possible); (C) Number...

  13. 50 CFR 218.14 - Requirements for monitoring and reporting.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    .... 218.14 Section 218.14 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND... outwards). For vessel-based surveys a passive acoustic system (hydrophone or towed array) could be used to... particular survey, the survey team shall collect: (A) Location of sighting; (B) Species (if not...

  14. 50 CFR 218.34 - Requirements for monitoring and reporting.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    .... 218.34 Section 218.34 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND... exclusion zone extending 2,000 yards outwards). For vessel-based surveys a passive acoustic system... detonation event. (iv) When conducting a particular survey, the survey team shall collect: (A) Location...

  15. 50 CFR 218.174 - Requirements for monitoring and reporting.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    .... 218.174 Section 218.174 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND... monitor HFAS and MFAS respectively at the DBRC Range site. (ii) For specified events, shore-based and vessel surveys shall be used 1 day prior to and 1-2 days post activity. (A) Shore-based Surveys:...

  16. 50 CFR 218.5 - Requirements for monitoring and reporting.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    .... 218.5 Section 218.5 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND... outwards). For vessel based surveys a passive acoustic system (hydrophone or towed array) could be used to... particular survey, the survey team shall collect: (A) Location of sighting; (B) Species (if not...

  17. 50 CFR 218.24 - Requirements for monitoring and reporting.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    .... 218.24 Section 218.24 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND... extending 2,000 yards outwards). For vessel based surveys, a passive acoustic system (hydrophone or towed... event. (iv) When conducting a particular survey, the survey team shall collect: (A) Location of...

  18. 49 CFR 218.24 - One-person crew.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false One-person crew. 218.24 Section 218.24...-person crew. (a) An engineer working alone as a one-person crew shall not perform duties on, under, or... unattended, the one-member crew shall secure the locomotive as follows: (i) The throttle is in the...

  19. 30 CFR 218.51 - How to make payments.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS AND INCENTIVES Oil and Gas, General § 218.51 How to... of a coal, geothermal, or offshore mineral (other than oil, gas or sulfur) lease, follow...

  20. 50 CFR 218.240 - Modifications to Letters of Authorization.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Array Sensor System Low Frequency Active (SURTASS LFA) Sonar § 218.240 Modifications to Letters of... sonar system from one ship to another, is not considered a substantial modification. (b) If...

  1. 50 CFR 218.237 - Applications for Letters of Authorization.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Array Sensor System Low Frequency Active (SURTASS LFA) Sonar § 218.237 Applications for Letters of... scheduled to begin conducting SURTASS LFA sonar operations or the previous Letter of Authorization...

  2. 50 CFR 218.240 - Modifications to Letters of Authorization.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Array Sensor System Low Frequency Active (SURTASS LFA) Sonar § 218.240 Modifications to Letters of... sonar system from one ship to another, is not considered a substantial modification. (b) If...

  3. 50 CFR 218.232 - Permissible methods of taking.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Low Frequency Active (SURTASS LFA) Sonar § 218.232 Permissible methods of taking. (a) Under Letters of.... This annual per-stock cap of 12 percent applies regardless of the number of SURTASS LFA sonar...

  4. 50 CFR 218.232 - Permissible methods of taking.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Low Frequency Active (SURTASS LFA) Sonar § 218.232 Permissible methods of taking. (a) Under Letters of.... This annual per-stock cap of 12 percent applies regardless of the number of SURTASS LFA sonar...

  5. 50 CFR 218.240 - Modifications to Letters of Authorization.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Array Sensor System Low Frequency Active (SURTASS LFA) Sonar § 218.240 Modifications to Letters of... sonar system from one ship to another, is not considered a substantial modification. (b) If...

  6. 50 CFR 218.237 - Applications for Letters of Authorization.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Array Sensor System Low Frequency Active (SURTASS LFA) Sonar § 218.237 Applications for Letters of... scheduled to begin conducting SURTASS LFA sonar operations or the previous Letter of Authorization...

  7. 50 CFR 218.232 - Permissible methods of taking.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Low Frequency Active (SURTASS LFA) Sonar § 218.232 Permissible methods of taking. (a) Under Letters of.... This annual per-stock cap of 12 percent applies regardless of the number of SURTASS LFA sonar...

  8. 50 CFR 218.188 - Modifications to Letters of Authorization.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... IMPORTING OF MARINE MAMMALS Taking Marine Mammals Incidental to U.S. Navy Mission Activities in the Naval Surface Warfare Center Panama City Division § 218.188 Modifications to Letters of Authorization....

  9. 50 CFR 218.188 - Modifications to Letters of Authorization.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... IMPORTING OF MARINE MAMMALS Taking Marine Mammals Incidental to U.S. Navy Mission Activities in the Naval Surface Warfare Center Panama City Division § 218.188 Modifications to Letters of Authorization....

  10. 50 CFR 218.185 - Applications for Letters of Authorization.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... IMPORTING OF MARINE MAMMALS Taking Marine Mammals Incidental to U.S. Navy Mission Activities in the Naval Surface Warfare Center Panama City Division § 218.185 Applications for Letters of Authorization....

  11. 50 CFR 218.188 - Modifications to Letters of Authorization.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... IMPORTING OF MARINE MAMMALS Taking Marine Mammals Incidental to U.S. Navy Mission Activities in the Naval Surface Warfare Center Panama City Division § 218.188 Modifications to Letters of Authorization....

  12. 50 CFR 218.188 - Modifications to Letters of Authorization.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... IMPORTING OF MARINE MAMMALS Taking Marine Mammals Incidental to U.S. Navy Mission Activities in the Naval Surface Warfare Center Panama City Division § 218.188 Modifications to Letters of Authorization....

  13. 50 CFR 218.185 - Applications for Letters of Authorization.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... IMPORTING OF MARINE MAMMALS Taking Marine Mammals Incidental to U.S. Navy Mission Activities in the Naval Surface Warfare Center Panama City Division § 218.185 Applications for Letters of Authorization....

  14. 50 CFR 218.185 - Applications for Letters of Authorization.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... IMPORTING OF MARINE MAMMALS Taking Marine Mammals Incidental to U.S. Navy Mission Activities in the Naval Surface Warfare Center Panama City Division § 218.185 Applications for Letters of Authorization....

  15. 50 CFR 218.185 - Applications for Letters of Authorization.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... IMPORTING OF MARINE MAMMALS Taking Marine Mammals Incidental to U.S. Navy Mission Activities in the Naval Surface Warfare Center Panama City Division § 218.185 Applications for Letters of Authorization....

  16. 50 CFR 218.16 - Letters of Authorization.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... MAMMALS Taking Marine Mammals Incidental to U.S. Navy Training in the Jacksonville Range Complex (JAX Range Complex) § 218.16 Letters of Authorization. (a) A Letter of Authorization, unless suspended...

  17. 50 CFR 218.7 - Letters of Authorization.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... MAMMALS Taking Marine Mammals Incidental to U.S. Navy Training in the Virginia Capes Range Complex (VACAPES Range Complex) § 218.7 Letters of Authorization. (a) A Letter of Authorization, unless...

  18. 50 CFR 218.106 - Applications for Letters of Authorization.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND... identified in § 218.100(c) (i.e., the Navy) must apply for and obtain either an initial Letter...

  19. 50 CFR 218.116 - Applications for Letters of Authorization.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND... identified in § 218.110(c) (i.e., the Navy) must apply for and obtain either an initial Letter...

  20. 50 CFR 218.126 - Applications for Letters of Authorization.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND...) conducting the activity identified in § 218.120(c) (i.e., the Navy) must apply for and obtain either...

  1. 50 CFR 218.117 - Letters of Authorization.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... MAMMALS Taking and Importing Marine Mammals; U.S. Navy's Northwest Training Range Complex (NWTRC) § 218... renewal of the Letter of Authorization shall be based on a determination that the total number of...

  2. 50 CFR 218.36 - Letters of Authorization.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... MAMMALS Taking Marine Mammals Incidental to U.S. Navy Training in the Gulf of Mexico Range Complex § 218... Letter of Authorization will be based on a determination that the total number of marine mammals taken...

  3. 50 CFR 218.26 - Letters of Authorization.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... MAMMALS Taking Marine Mammals Incidental to U.S. Navy Training in the Cherry Point Range Complex § 218.26... Authorization will be based on a determination that the total number of marine mammals taken by the activity...

  4. 50 CFR 218.176 - Letters of Authorization.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Complex and the Associated Proposed Extensions Study Area § 218.176 Letters of Authorization. (a) A Letter... determination that the total number of marine mammals taken by the activity as a whole will have no more than...

  5. 4. INTERIOR VIEW NORTHWEST, ALLEYWAY PASSAGE BETWEEN 216 AND 218 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. INTERIOR VIEW NORTHWEST, ALLEYWAY PASSAGE BETWEEN 216 AND 218 KING STREET SHOWING MASONRY ARCHED CONSTRUCTION SUPPORTING UPPER STORIES - King Street, 200 Block, 216 King Street (Commercial Building), Wilmington, New Castle County, DE

  6. 3. ELEVATION VIEW OF THE SOUTH FACADE OF BUILDING 218, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. ELEVATION VIEW OF THE SOUTH FACADE OF BUILDING 218, LOOKING WEST-NORTHWEST. - Mill Valley Air Force Station, Consolidated Open Mess, East Ridgecrest Boulevard, Mount Tamalpais, Mill Valley, Marin County, CA

  7. Alternating parity structure in doubly odd /sup 218/Ac

    SciTech Connect

    Debray, M.E.; Davidson, M.; Kreiner, A.J.; Davidson, J.; Falcone, G.; Hojman, D.; Santos, D.

    1989-03-01

    States in doubly odd /sup 218/Ac have been studied using in-beam ..cap alpha..-, ..gamma..-, and e/sup -/-spectroscopy techniques mainly through the /sup 209/Bi(/sup 12/C,3n)= fusion-evaporation reaction. /sup 218/Ac shows a band structure, with interleaved states of alternating parities connected by enhanced B(E1) transitions, which is strikingly similar to the one in its isotone /sup 217/Ra.

  8. (211)Astatine-Conjugated Monoclonal CD45 Antibody-Based Nonmyeloablative Conditioning for Stem Cell Gene Therapy.

    PubMed

    Burtner, Christopher R; Chandrasekaran, Devikha; Santos, Erlinda B; Beard, Brian C; Adair, Jennifer E; Hamlin, Donald K; Wilbur, D Scott; Sandmaier, Brenda M; Kiem, Hans-Peter

    2015-06-01

    Most hematopoietic stem cell gene therapy studies require host conditioning to allow for efficient engraftment of gene-modified cells. Conditioning regimens with lower treatment-related toxicities are especially relevant for the treatment of nonmalignant blood disorders, such as hemoglobinopathies and immunodeficiencies, and for patients who are otherwise ineligible for conventional high-dose conditioning. Radioimmunotherapy, which employs an α- or a β-emitting radionuclide conjugated to a targeting antibody, is effective for delivering cytotoxic doses of radiation to a cell type of interest while minimizing off-target toxicity. Here, we demonstrate the feasibility of using a nonmyeloablative dose of a monoclonal anti-CD45 antibody conjugated to the α-emitter Astatine-211 ((211)At) to promote engraftment of an autologous gene-modified stem cell graft in the canine model. The doses used provided myelosuppression with rapid autologous recovery and minimal off-target toxicity. Engraftment levels were low in all dogs and reflected the low numbers of gene-modified cells infused. Our data suggest that a cell dose exceeding 1×10(6) cells/kg be used with nonmyeloablative doses of (211)At-anti-CD45 monoclonal antibodies for sustained engraftment in the dog model.

  9. Cytotoxicity of alpha-particle-emitting astatine-211-labelled antibody in tumour spheroids: no effect of hyperthermia.

    PubMed

    Hauck, M L; Larsen, R H; Welsh, P C; Zalutsky, M R

    1998-03-01

    The high linear energy transfer, alpha-particle-emitting radionuclide astatine-211 (211At) is of interest for certain therapeutic applications; however, because of the 55- to 70-microm path length of its alpha-particles, achieving homogeneous tracer distribution is critical. Hyperthermia may enhance the therapeutic efficacy of alpha-particle endoradiotherapy if it can improve tracer distribution. In this study, we have investigated whether hyperthermia increased the cytotoxicity of an 211At-labelled monoclonal antibody (MAb) in tumour spheroids with a radius (approximately 100 microm) greater than the range of 211At alpha-particles. Hyperthermia for 1 h at 42 degrees C was used because this treatment itself resulted in no regrowth delay. Radiolabelled chimeric MAb 81C6 reactive with the extracellular matrix antigen tenascin was added to spheroids grown from the D-247 MG human glioma cell line at activity concentrations ranging from 0.125 to 250 kBq ml(-1). A significant regrowth delay was observed at 125 and 250 kBq ml(-1) in both hyperthermia-treated and untreated spheroids. For groups receiving hyperthermia, no increase in cytotoxicity was seen compared with normothermic controls at any activity concentration. These results and those from autoradiographs indicate that hyperthermia at 42 degrees C for 1 h had no significant effect on the uptake or distribution of this antitenascin MAb in D-247 MG spheroids.

  10. Cell growth kinetics of the human cell line Colo-205 irradiated with photons and astatine-211 alpha-particles.

    PubMed

    Palm, S; Andersson, H; Bäck, T; Claesson, I; Delle, U; Hultborn, R; Jacobsson, L; Köpf, I; Lindegren, S

    2000-01-01

    Cell growth kinetics following Astatine-211 (211At, alpha-particle emitter) and photon irradiation were studied for the human colorectal cell line Colo-205. A growth assay using 96-well plates was chosen. The growth kinetics could be simulated by assuming certain fractions of cells with various proliferative capacities, i.e. from none up to 5 cell doublings, in addition to the defined survivors with remaining unlimited clonogenic capacity. No significant difference in cell growth characteristics was seen between 211At and photon irradiation. The cell doubling time, as calculated from the increment in optical density, was compared with the results from BrdU experiments in the early phases of growth (Tpot = 18.5 +/- 0.6 h for LDR (low dose rate) photon irradiated and 20.3 +/- 0.8 hours for sham-irradiated cells 40-45 hours post-irradiation) confirming the transient accelerated growth of irradiated cells. No statistically significant difference in growth was found between LDR, MDR (medium dose rate) and HDR (high dose rate) photon irradiation.

  11. 211Astatine-Conjugated Monoclonal CD45 Antibody-Based Nonmyeloablative Conditioning for Stem Cell Gene Therapy

    PubMed Central

    Burtner, Christopher R.; Chandrasekaran, Devikha; Santos, Erlinda B.; Beard, Brian C.; Adair, Jennifer E.; Hamlin, Donald K.; Wilbur, D. Scott; Sandmaier, Brenda M.

    2015-01-01

    Abstract Most hematopoietic stem cell gene therapy studies require host conditioning to allow for efficient engraftment of gene-modified cells. Conditioning regimens with lower treatment-related toxicities are especially relevant for the treatment of nonmalignant blood disorders, such as hemoglobinopathies and immunodeficiencies, and for patients who are otherwise ineligible for conventional high-dose conditioning. Radioimmunotherapy, which employs an α- or a β-emitting radionuclide conjugated to a targeting antibody, is effective for delivering cytotoxic doses of radiation to a cell type of interest while minimizing off-target toxicity. Here, we demonstrate the feasibility of using a nonmyeloablative dose of a monoclonal anti-CD45 antibody conjugated to the α-emitter Astatine-211 (211At) to promote engraftment of an autologous gene-modified stem cell graft in the canine model. The doses used provided myelosuppression with rapid autologous recovery and minimal off-target toxicity. Engraftment levels were low in all dogs and reflected the low numbers of gene-modified cells infused. Our data suggest that a cell dose exceeding 1×106 cells/kg be used with nonmyeloablative doses of 211At-anti-CD45 monoclonal antibodies for sustained engraftment in the dog model. PMID:25919226

  12. Cytotoxicity of alpha-particle-emitting astatine-211-labelled antibody in tumour spheroids: no effect of hyperthermia.

    PubMed Central

    Hauck, M. L.; Larsen, R. H.; Welsh, P. C.; Zalutsky, M. R.

    1998-01-01

    The high linear energy transfer, alpha-particle-emitting radionuclide astatine-211 (211At) is of interest for certain therapeutic applications; however, because of the 55- to 70-microm path length of its alpha-particles, achieving homogeneous tracer distribution is critical. Hyperthermia may enhance the therapeutic efficacy of alpha-particle endoradiotherapy if it can improve tracer distribution. In this study, we have investigated whether hyperthermia increased the cytotoxicity of an 211At-labelled monoclonal antibody (MAb) in tumour spheroids with a radius (approximately 100 microm) greater than the range of 211At alpha-particles. Hyperthermia for 1 h at 42 degrees C was used because this treatment itself resulted in no regrowth delay. Radiolabelled chimeric MAb 81C6 reactive with the extracellular matrix antigen tenascin was added to spheroids grown from the D-247 MG human glioma cell line at activity concentrations ranging from 0.125 to 250 kBq ml(-1). A significant regrowth delay was observed at 125 and 250 kBq ml(-1) in both hyperthermia-treated and untreated spheroids. For groups receiving hyperthermia, no increase in cytotoxicity was seen compared with normothermic controls at any activity concentration. These results and those from autoradiographs indicate that hyperthermia at 42 degrees C for 1 h had no significant effect on the uptake or distribution of this antitenascin MAb in D-247 MG spheroids. Images Figure 4 Figure 5 PMID:9514054

  13. Stability and in vivo behavior of Rh[16aneS4-diol]211At complex: a potential precursor for astatine radiopharmaceuticals

    PubMed Central

    Pruszynski, Marek; Łyczko, Monika; Bilewicz, Aleksander; Zalutsky, Michael R.

    2015-01-01

    Introduction The heavy halogen 211At is of great interest for targeted radiotherapy because it decays by the emission of short-range, high-energy α-particles. However, many astatine compounds that have been synthesized are unstable in vivo, providing motivation for seeking other 211At labeling strategies. One relatively unexplored approach is to utilize prosthetic groups based on astatinated rhodium(III) complex stabilized with a tetrathioether macrocyclic ligand - Rh[16aneS4-diol]211At. The purpose of the current study was to evaluate the in vitro and in vivo stability of this complex in comparison to its iodine analogue - Rh[16aneS4-diol]131I. Methods Rh[16aneS4-diol]211At and Rh[16aneS4-diol]131I complexes were synthesized and purified by HPLC. The stability of both complexes was evaluated in vitro by incubation in phosphate-buffered saline (PBS) and human serum at different temperatures. The in vivo behavior of the two radiohalogenated complexes was assessed by a paired-label biodistribution study in normal Balb/c mice. Results Both complexes were synthesized in high yield and purity. Almost no degradation was observed for Rh[16aneS4-diol]131I in PBS over a 72 h incubation. The astatinated analogue exhibited good stability in PBS over 14 h. A slow decline in the percentage of intact complex was observed for both tracers in human serum. In the biodistribution study, retention of 211At in most tissues was higher than that of 131I at all time points, especially in spleen and lungs. Renal clearance of Rh[16aneS4-diol]211At and Rh[16aneS4-diol]131I predominated, with 84.1 ± 2.3% and 94.6 ± 0.9% of injected dose excreted via the urine at 4 h. Conclusions The Rh[16aneS4-diol]211At complex might be useful for constructing prosthetic groups for the astatination of biomolecules and further studies are planned to evaluate this possibility. PMID:25687450

  14. Single-cell irradiation from [211At] astatine-labeled C215 monoclonal antibody: improved estimates of radiosensitivity from measurements on cellular uptake and retention.

    PubMed

    Palm, Stig; Bäck, Tom; Claesson, Ingela; Delle, Ulla; Hultborn, Ragnar; Lindegren, Sture; Jacobsson, Lars

    2003-01-01

    New data on the biological effect of 211At-C215 monoclonal antibody in a slowly rotating, widely dispersed single-cell suspension of the human cancer cell line Colo-205 is presented. Cell growth curves of each experiment were used to calculate an apparent cell survival after irradiation. Uptake measurements provided the data needed to calculate the average number of 211At decays per cell in the cell suspension. The results from each experiment were then fit to a mono-exponential function. From the exponential fit, an average of 35 +/- 2 (SD) astatine-211 decays per cell are required for 37% apparent cell survival (D0).

  15. Advances on the Determination of the Astatine Pourbaix Diagram: Predomination of AtO(OH)2 (-) over At(-) in Basic Conditions.

    PubMed

    Sergentu, Dumitru-Claudiu; Teze, David; Sabatié-Gogova, Andréa; Alliot, Cyrille; Guo, Ning; Bassal, Fadel; Silva, Isidro Da; Deniaud, David; Maurice, Rémi; Champion, Julie; Galland, Nicolas; Montavon, Gilles

    2016-02-24

    It is generally assumed that astatide (At(-) ) is the predominant astatine species in basic aqueous media. This assumption is questioned in non-complexing and non-reductive aqueous solutions by means of high-pressure anion-exchange chromatography. Contrary to what is usually believed, astatide is found to be a minor species at pH=11. A different species, which also bears a single negative charge, becomes predominant when the pH is increased beyond 7. Using competition experiments, an equilibrium constant value of 10(-6.9) has been determined for the formation of this species from AtO(OH) with the exchange of one proton. The identification of this species, AtO(OH)2 (-) , is achieved through relativistic quantum mechanical calculations, which rule out the significant formation of the AtO2 (-) species, while leading to a hydrolysis constant of AtO(OH) in excellent agreement with experiment when the AtO(OH)2 (-) species is considered. Beyond the completion of the Pourbaix diagram of astatine, this new information is of interest for the development of (211) At radiolabeling protocols.

  16. 50 CFR 218.235 - Requirements for monitoring.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Low Frequency Active (SURTASS LFA) Sonar § 218.235 Requirements for monitoring. (a) The Holder of a...) during operations that employ SURTASS LFA sonar in the active mode. The SURTASS vessels shall have... frequency passive SURTASS sonar to listen for vocalizing marine mammals; and (3) Use the HF/M3 active...

  17. Measurement of airborne {sup 218}Po - A Bayesian approach

    SciTech Connect

    Groer, P.G.; Lo, Y.

    1996-12-01

    The standard mathematical treatment of the buildup and decay of airborne radionuclides on a filter paper uses the solutions of the so-called bateman equations adapted to the sampling process. The equations can be interpreted as differential equations for the expectation of an underlying stochastic process, which describes the random fluctuations in the accumulation and decay of the sampled radioactive atoms. The process for the buildup and decay of airborne {sup 218}Po can be characterized as an {open_quotes}immigration-death process{close_quotes} in the widely adopted, biologically based jargon. The probability distribution for the number of {sup 218}Po atoms, accumulated after sampling time t, is Poisson. We show that the distribution of the number of counts, registered by a detector with efficiency {epsilon} during a counting period T after the end of sampling, it also Poisson, with mean dependent on {epsilon},t,T, the flowrate and N{sub o}, the number of airborne {sup 218}Po atoms per unit volume. This Poisson distribution was used to construct the likelihood given the observed number of counts. After inversion with Bayes` Theorem we obtained the posterior density for N{sub o}. This density characterizes the remaining uncertainty about the measured under of {sup 218}Po atoms per unit volume of air. 6 refs., 3 figs., 1 tab.

  18. 50 CFR 218.235 - Requirements for monitoring.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Low Frequency Active (SURTASS LFA) Sonar § 218.235 Requirements for monitoring. (a) The Holder of a...) during operations that employ SURTASS LFA sonar in the active mode. The SURTASS vessels shall have... frequency passive SURTASS sonar to listen for vocalizing marine mammals; and (3) Use the HF/M3 active...

  19. 50 CFR 218.235 - Requirements for monitoring.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Low Frequency Active (SURTASS LFA) Sonar § 218.235 Requirements for monitoring. (a) The Holder of a...) during operations that employ SURTASS LFA sonar in the active mode. The SURTASS vessels shall have... frequency passive SURTASS sonar to listen for vocalizing marine mammals; and (3) Use the HF/M3 active...

  20. 36 CFR 218.10 - Objection time periods and process.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... legal notice of the EA or final EIS in the newspaper of record or the publication date of the notice in... of the EA or final EIS in the newspaper of record or Federal Register (§ 218.5(c)) is the first day of the objection-filing period. (3) The publication date of the legal notice of the EA or final...

  1. 33 CFR 157.218 - Dedicated clean ballast tanks: Alterations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Dedicated clean ballast tanks... CARRYING OIL IN BULK Dedicated Clean Ballast Tanks on Tank Vessels General § 157.218 Dedicated clean ballast tanks: Alterations. The dedicated clean ballast tanks or equipment on a tank vessel that has...

  2. 36 CFR 218.9 - Objections set aside from review.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Objections set aside from... Reduction Projects Authorized by the Healthy Forests Restoration Act of 2003 § 218.9 Objections set aside from review. (a) The reviewing officer must set aside and not review an objection when one or more...

  3. 36 CFR 218.9 - Objections set aside from review.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false Objections set aside from... Reduction Projects Authorized by the Healthy Forests Restoration Act of 2003 § 218.9 Objections set aside from review. (a) The reviewing officer must set aside and not review an objection when one or more...

  4. 36 CFR 218.9 - Objections set aside from review.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false Objections set aside from... Reduction Projects Authorized by the Healthy Forests Restoration Act of 2003 § 218.9 Objections set aside from review. (a) The reviewing officer must set aside and not review an objection when one or more...

  5. 50 CFR 218.16 - Letters of Authorization.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... MAMMALS Taking Marine Mammals Incidental to U.S. Navy Training in the Jacksonville Range Complex (JAX Range Complex) § 218.16 Letters of Authorization. (a) A Letter of Authorization, unless suspended or... and renewal of the Letter of Authorization will be based on a determination that the total number...

  6. 50 CFR 218.7 - Letters of Authorization.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... MAMMALS Taking Marine Mammals Incidental to U.S. Navy Training in the Virginia Capes Range Complex (VACAPES Range Complex) § 218.7 Letters of Authorization. (a) A Letter of Authorization, unless suspended... and renewal of the Letter of Authorization will be based on a determination that the total number...

  7. 20 CFR 218.30 - Separation, displacement or dismissal allowance.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true Separation, displacement or dismissal..., Spouse, or Divorced Spouse Annuity Beginning Date § 218.30 Separation, displacement or dismissal allowance. (a) General. When an employee receives a separation, displacement or dismissal allowance from...

  8. 20 CFR 218.30 - Separation, displacement or dismissal allowance.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true Separation, displacement or dismissal..., Spouse, or Divorced Spouse Annuity Beginning Date § 218.30 Separation, displacement or dismissal allowance. (a) General. When an employee receives a separation, displacement or dismissal allowance from...

  9. 20 CFR 218.30 - Separation, displacement or dismissal allowance.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false Separation, displacement or dismissal..., Spouse, or Divorced Spouse Annuity Beginning Date § 218.30 Separation, displacement or dismissal allowance. (a) General. When an employee receives a separation, displacement or dismissal allowance from...

  10. 20 CFR 218.30 - Separation, displacement or dismissal allowance.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false Separation, displacement or dismissal..., Spouse, or Divorced Spouse Annuity Beginning Date § 218.30 Separation, displacement or dismissal allowance. (a) General. When an employee receives a separation, displacement or dismissal allowance from...

  11. 20 CFR 218.30 - Separation, displacement or dismissal allowance.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Separation, displacement or dismissal..., Spouse, or Divorced Spouse Annuity Beginning Date § 218.30 Separation, displacement or dismissal allowance. (a) General. When an employee receives a separation, displacement or dismissal allowance from...

  12. 32 CFR 218.3 - Dose reconstruction methodology.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... ATMOSPHERIC NUCLEAR TEST PROGRAM (1945-1962) § 218.3 Dose reconstruction methodology. (a) Concept. The... characteristics, as well as the normal spread in the available data pertaining to the radiation environment, an..., group size, and available data. Due to the large amounts of data, an automated...

  13. 32 CFR 218.3 - Dose reconstruction methodology.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... ATMOSPHERIC NUCLEAR TEST PROGRAM (1945-1962) § 218.3 Dose reconstruction methodology. (a) Concept. The... characteristics, as well as the normal spread in the available data pertaining to the radiation environment, an..., group size, and available data. Due to the large amounts of data, an automated...

  14. 32 CFR 218.3 - Dose reconstruction methodology.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... ATMOSPHERIC NUCLEAR TEST PROGRAM (1945-1962) § 218.3 Dose reconstruction methodology. (a) Concept. The... characteristics, as well as the normal spread in the available data pertaining to the radiation environment, an..., group size, and available data. Due to the large amounts of data, an automated...

  15. 32 CFR 218.3 - Dose reconstruction methodology.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... ATMOSPHERIC NUCLEAR TEST PROGRAM (1945-1962) § 218.3 Dose reconstruction methodology. (a) Concept. The... characteristics, as well as the normal spread in the available data pertaining to the radiation environment, an..., group size, and available data. Due to the large amounts of data, an automated...

  16. 32 CFR 218.3 - Dose reconstruction methodology.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... ATMOSPHERIC NUCLEAR TEST PROGRAM (1945-1962) § 218.3 Dose reconstruction methodology. (a) Concept. The... characteristics, as well as the normal spread in the available data pertaining to the radiation environment, an..., group size, and available data. Due to the large amounts of data, an automated...

  17. 37 CFR 2.18 - Correspondence, with whom held.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Correspondence, with whom... Persons § 2.18 Correspondence, with whom held. (a) Establishing the correspondence address. (1) If a... correspondence to the practitioner designated in the power. (2) If a practitioner qualified under § 11.14 of...

  18. 37 CFR 2.18 - Correspondence, with whom held.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2012-07-01 2012-07-01 false Correspondence, with whom... Persons § 2.18 Correspondence, with whom held. (a) Establishing the correspondence address. (1) If a... correspondence to the practitioner designated in the power. (2) If a practitioner qualified under § 11.14 of...

  19. 37 CFR 2.18 - Correspondence, with whom held.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Correspondence, with whom... Persons § 2.18 Correspondence, with whom held. (a) Establishing the correspondence address. (1) If a... correspondence to the practitioner designated in the power. (2) If a practitioner qualified under § 11.14 of...

  20. 37 CFR 2.18 - Correspondence, with whom held.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Correspondence, with whom... Persons § 2.18 Correspondence, with whom held. (a) Establishing the correspondence address. (1) If a... correspondence to the practitioner designated in the power. (2) If a practitioner qualified under § 11.14 of...

  1. 37 CFR 2.18 - Correspondence, with whom held.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Correspondence, with whom... Persons § 2.18 Correspondence, with whom held. (a) Establishing the correspondence address. (1) If a... correspondence to the practitioner designated in the power. (2) If a practitioner qualified under § 11.14 of...

  2. 10 CFR 72.218 - Termination of licenses.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE General License for Storage of Spent Fuel at Power Reactor Sites § 72.218 Termination of licenses. (a) The notification regarding the program for the management of spent fuel at the reactor required by § 50.54(bb)...

  3. 10 CFR 72.218 - Termination of licenses.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE General License for Storage of Spent Fuel at Power Reactor Sites § 72.218 Termination of licenses. (a) The notification regarding the program for the management of spent fuel at the reactor required by § 50.54(bb)...

  4. 50 CFR 300.218 - Reporting and recordkeeping requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... fishing vessel of the United States used for commercial fishing for HMS in the Pacific Ocean must maintain... INTERNATIONAL FISHERIES REGULATIONS Western and Central Pacific Fisheries for Highly Migratory Species § 300.218... reporting requirements as listed below: (i) Western Pacific pelagic fisheries. Fishing activities subject...

  5. 50 CFR 300.218 - Reporting and recordkeeping requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... fishing vessel of the United States used for commercial fishing for HMS in the Pacific Ocean must maintain... INTERNATIONAL FISHERIES REGULATIONS Western and Central Pacific Fisheries for Highly Migratory Species § 300.218... reporting requirements as listed below: (i) Western Pacific pelagic fisheries. Fishing activities subject...

  6. 50 CFR 300.218 - Reporting and recordkeeping requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... fishing vessel of the United States used for commercial fishing for HMS in the Pacific Ocean must maintain... INTERNATIONAL FISHERIES REGULATIONS Western and Central Pacific Fisheries for Highly Migratory Species § 300.218... reporting requirements as listed below: (i) Western Pacific pelagic fisheries. Fishing activities subject...

  7. 48 CFR 218.271 - Head of contracting activity determinations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Head of contracting... Emergency Acquisition Flexibilities 218.271 Head of contracting activity determinations. For contract..., biological, chemical, or radiological attack, the term “head of the agency” is replaced with “head of...

  8. 48 CFR 218.270 - Head of contracting activity determinations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Head of contracting... Emergency Acquisition Flexibilities 218.270 Head of contracting activity determinations. For contract..., biological, chemical, or radiological attack, the term “head of the agency” is replaced with “head of...

  9. 48 CFR 218.271 - Head of contracting activity determinations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Head of contracting... Emergency Acquisition Flexibilities 218.271 Head of contracting activity determinations. For contract..., biological, chemical, or radiological attack, the term “head of the agency” is replaced with “head of...

  10. 48 CFR 218.271 - Head of contracting activity determinations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Head of contracting... Emergency Acquisition Flexibilities 218.271 Head of contracting activity determinations. For contract..., biological, chemical, or radiological attack, the term “head of the agency” is replaced with “head of...

  11. 48 CFR 218.271 - Head of contracting activity determinations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Head of contracting... Emergency Acquisition Flexibilities 218.271 Head of contracting activity determinations. For contract..., biological, chemical, or radiological attack, the term “head of the agency” is replaced with “head of...

  12. 33 CFR 157.218 - Dedicated clean ballast tanks: Alterations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Dedicated clean ballast tanks... CARRYING OIL IN BULK Dedicated Clean Ballast Tanks on Tank Vessels General § 157.218 Dedicated clean ballast tanks: Alterations. The dedicated clean ballast tanks or equipment on a tank vessel that has...

  13. 33 CFR 157.218 - Dedicated clean ballast tanks: Alterations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Dedicated clean ballast tanks... CARRYING OIL IN BULK Dedicated Clean Ballast Tanks on Tank Vessels General § 157.218 Dedicated clean ballast tanks: Alterations. The dedicated clean ballast tanks or equipment on a tank vessel that has...

  14. 33 CFR 157.218 - Dedicated clean ballast tanks: Alterations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Dedicated clean ballast tanks... CARRYING OIL IN BULK Dedicated Clean Ballast Tanks on Tank Vessels General § 157.218 Dedicated clean ballast tanks: Alterations. The dedicated clean ballast tanks or equipment on a tank vessel that has...

  15. 33 CFR 157.218 - Dedicated clean ballast tanks: Alterations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Dedicated clean ballast tanks... CARRYING OIL IN BULK Dedicated Clean Ballast Tanks on Tank Vessels General § 157.218 Dedicated clean ballast tanks: Alterations. The dedicated clean ballast tanks or equipment on a tank vessel that has...

  16. 50 CFR 218.82 - Permissible methods of taking.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... MAMMALS Taking and Importing Marine Mammals; U.S. Navy's Atlantic Fleet Training and Testing (AFTT) § 218...) Gray seal (Halichoerus grypus)—14,511. (B) Harbor seal (Phoca vitulina)—39,519. (C) Harp seal (Pagophilus groenlanica)—16,319. (D) Hooded seal (Cystophora cristata)—1,472. (E) Ringed seal (Pusa...

  17. 50 CFR 218.122 - Permissible methods of taking.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ....106 and 218.127 of this chapter, the Holder of the Letter of Authorization (hereinafter “Navy”) may... californianus)—10 (an average of 2 annually); (C) Harbor seal (Phoca vitulina richardsi)—10 (an average of 2 annually); (D) Northern elephant seal (Mirounga angustirostris)—10,345 (an average of 2,069 annually);...

  18. 50 CFR 218.122 - Permissible methods of taking.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ....106 and 218.127 of this chapter, the Holder of the Letter of Authorization (hereinafter “Navy”) may... californianus)—10 (an average of 2 annually); (C) Harbor seal (Phoca vitulina richardsi)—10 (an average of 2 annually); (D) Northern elephant seal (Mirounga angustirostris)—10,345 (an average of 2,069 annually);...

  19. 50 CFR 218.122 - Permissible methods of taking.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ....106 and 218.127 of this chapter, the Holder of the Letter of Authorization (hereinafter “Navy”) may... californianus)—10 (an average of 2 annually); (C) Harbor seal (Phoca vitulina richardsi)—10 (an average of 2 annually); (D) Northern elephant seal (Mirounga angustirostris)—10,345 (an average of 2,069 annually);...

  20. 50 CFR 218.122 - Permissible methods of taking.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ....106 and 218.127 of this chapter, the Holder of the Letter of Authorization (hereinafter “Navy”) may... californianus)—10 (an average of 2 annually); (C) Harbor seal (Phoca vitulina richardsi)—10 (an average of 2 annually); (D) Northern elephant seal (Mirounga angustirostris)—10,345 (an average of 2,069 annually);...

  1. 49 CFR 218.77 - Remotely controlled switches.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Protection of Occupied Camp Cars § 218... that a camp car is to be placed on a particular track, he shall line such switch against movement to... controlling the switch before informing the person in charge of the camp car occupants that protection...

  2. 49 CFR 218.77 - Remotely controlled switches.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Protection of Occupied Camp Cars § 218... that a camp car is to be placed on a particular track, he shall line such switch against movement to... controlling the switch before informing the person in charge of the camp car occupants that protection...

  3. 18 CFR 157.218 - Changes in customer name.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Changes in customer... Act for Certain Transactions and Abandonment § 157.218 Changes in customer name. (a) Automatic... reflect the change in the name of an existing customer, if the certificate holder has filed any...

  4. 20 CFR 725.218 - Conditions of entitlement; child.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 4 2012-04-01 2012-04-01 false Conditions of entitlement; child. 725.218... Conditions of entitlement; child. (a) An individual is entitled to benefits where he or she meets the... the child of a deceased miner who: (1) Was receiving benefits under section 415 or part C of title...

  5. 20 CFR 725.218 - Conditions of entitlement; child.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 4 2013-04-01 2013-04-01 false Conditions of entitlement; child. 725.218... Conditions of entitlement; child. (a) An individual is entitled to benefits where he or she meets the... the child of a deceased miner who: (1) Was receiving benefits under section 415 or part C of title...

  6. 20 CFR 725.218 - Conditions of entitlement; child.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Conditions of entitlement; child. 725.218... Conditions of entitlement; child. (a) An individual is entitled to benefits where he or she meets the... the child of a deceased miner who: (1) Was receiving benefits under section 415 or part C of title...

  7. 20 CFR 725.218 - Conditions of entitlement; child.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false Conditions of entitlement; child. 725.218... Conditions of entitlement; child. (a) An individual is entitled to benefits where he or she meets the... the child of a deceased miner who: (1) Is determined to have died due to pneumoconiosis; or (2)...

  8. 20 CFR 725.218 - Conditions of entitlement; child.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Conditions of entitlement; child. 725.218... Conditions of entitlement; child. (a) An individual is entitled to benefits where he or she meets the... the child of a deceased miner who: (1) Was receiving benefits under section 415 or part C of title...

  9. 50 CFR 218.236 - Requirements for reporting.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Section 218.236 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC... Letter of Authorization must submit classified and unclassified quarterly mission reports to the Director... Authorization. Each quarterly mission report will include all active-mode missions completed during that...

  10. MiR-218 Mediates tumorigenesis and metastasis: Perspectives and implications

    SciTech Connect

    Lu, Ying-fei; Zhang, Li; Waye, Mary Miu Yee; Fu, Wei-ming; Zhang, Jin-fang

    2015-05-15

    MicroRNAs (miRNAs) are a class of small non-coding RNAs that negatively regulate gene expression at the post-transcriptional level. As a highly conserved miRNA across a variety of species, microRNA-218 (miR-218) was found to play pivotal roles in tumorigenesis and progression. A group of evidence has demonstrated that miR-218 acts as a tumor suppressor by targeting many oncogenes related to proliferation, apoptosis and invasion. In this review, we provide a complex overview of miR-218, including its regulatory mechanisms, known functions in cancer and future challenges as a potential therapeutic target in human cancers. - Highlights: • miR-218 is frequently down regulated in multiple cancers. • miR-218 plays pivotal roles in carcinogenesis. • miR-218 mediates proliferation, apoptosis, metastasis, invasion, etc. • miR-218 mediates tumorigenesis and metastasis via multiple pathways.

  11. 12 CFR 218.741 - Exemption for banks effecting transactions in money market funds.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... money market funds. 218.741 Section 218.741 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS... EXCHANGE ACT OF 1934 (REGULATION R) § 218.741 Exemption for banks effecting transactions in money market... issued by a money market fund, provided that: (1) The bank either (i) Provides the customer, directly...

  12. 75 FR 3927 - Proposed Information Collection Request for the ETA 218, Benefit Rights and Experience Report...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-25

    ... Information Collection Request for the ETA 218, Benefit Rights and Experience Report; Comment Request on... unemployment compensation programs. The data in the ETA 218, Benefit Rights and Experience Report, includes... extension for the collection of the ETA 218, Benefit Rights and Experience report. Comments are...

  13. 49 CFR 218.103 - Hand-operated switches, including crossover switches.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Hand-operated switches, including crossover switches. 218.103 Section 218.103 Transportation Other Regulations Relating to Transportation (Continued... Equipment, Switches, and Fixed Derails § 218.103 Hand-operated switches, including crossover switches....

  14. 49 CFR 218.105 - Additional operational requirements for hand-operated main track switches.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...-operated main track switches. 218.105 Section 218.105 Transportation Other Regulations Relating to... PRACTICES Handling Equipment, Switches, and Fixed Derails § 218.105 Additional operational requirements for hand-operated main track switches. (a) Each railroad shall adopt and comply with an operating...

  15. 49 CFR 218.105 - Additional operational requirements for hand-operated main track switches.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...-operated main track switches. 218.105 Section 218.105 Transportation Other Regulations Relating to... PRACTICES Handling Equipment, Switches, and Fixed Derails § 218.105 Additional operational requirements for hand-operated main track switches. (a) Each railroad shall adopt and comply with an operating...

  16. 49 CFR 218.107 - Additional operational requirements for hand-operated crossover switches.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...-operated crossover switches. 218.107 Section 218.107 Transportation Other Regulations Relating to... PRACTICES Handling Equipment, Switches, and Fixed Derails § 218.107 Additional operational requirements for hand-operated crossover switches. (a) Each railroad shall adopt and comply with an operating rule...

  17. 49 CFR 218.107 - Additional operational requirements for hand-operated crossover switches.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...-operated crossover switches. 218.107 Section 218.107 Transportation Other Regulations Relating to... PRACTICES Handling Equipment, Switches, and Fixed Derails § 218.107 Additional operational requirements for hand-operated crossover switches. (a) Each railroad shall adopt and comply with an operating rule...

  18. 49 CFR 218.103 - Hand-operated switches, including crossover switches.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Hand-operated switches, including crossover switches. 218.103 Section 218.103 Transportation Other Regulations Relating to Transportation (Continued... Equipment, Switches, and Fixed Derails § 218.103 Hand-operated switches, including crossover switches....

  19. 49 CFR Appendix A to Part 218 - Schedule of Civil Penalties 1

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 218 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Pt. 218, App. A Appendix A to Part 218...: (a) Protection provided except that signal not displayed at switch 2,000 4,000 (b) through (e)...

  20. mir-218-2 promotes glioblastomas growth, invasion and drug resistance by targeting CDC27

    PubMed Central

    Zhou, Junchen; Zhou, Shuai; li, Li; Guo, Xuyan; Feng, Guoying; Ma, Ze; Huang, Wenhua; Huang, Fei

    2017-01-01

    Glioma has become a significant global health problem with substantial morbidity and mortality, underscoring the importance of elucidating its underlying molecular mechanisms. Recent studies have identified mir-218 as an anti-oncogene; however, the specific functions of mir-218-1 and mir-218-2 remain unknown, especially the latter. The objective of this study was to further investigate the role of mir-218-2 in glioma. Our results indicated that mir-218-2 is highly overexpressed in glioma. Furthermore, we showed that mir-218-2 is positively correlated with the growth, invasion, migration, and drug susceptibility (to β-lapachone) of glioma cells. In vitro, the overexpression of mir-218-2 promoted glioma cell proliferation, invasion, and migration. In addition, the overexpression of mir-218-2 in vivo was found to increase glioma tumor growth. Accordingly, the inhibition of mir-218-2 resulted in the opposite effects. Cell division cycle 27 (CDC27), the downstream target of mir-218-2, is involved in the regulation of glioma cells. Our results indicate that the overexpression of CDC27 counteracted the function of mir-218-2 in glioma cells. These novel findings provide new insight in the application of mir-218-2 as a potential glioma treatment. PMID:27974673

  1. 49 CFR Appendix C to Part 218 - Statement of Agency Enforcement Policy on Tampering

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Tampering C Appendix C to Part 218 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Pt. 218, App. C Appendix C to Part 218—Statement of Agency Enforcement Policy on Tampering The Rail Safety Improvement...

  2. 50 CFR 218.177 - Renewal of Letters of Authorization and adaptive management.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... adaptive management. 218.177 Section 218.177 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE..., Development, Test, and Evaluation Activities in the Naval Sea System Command (NAVSEA) Naval Undersea Warfare Center (NUWC) Keyport Range Complex and the Associated Proposed Extensions Study Area § 218.177...

  3. 50 CFR 218.177 - Renewal of Letters of Authorization and adaptive management.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... adaptive management. 218.177 Section 218.177 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE..., Development, Test, and Evaluation Activities in the Naval Sea System Command (NAVSEA) Naval Undersea Warfare Center (NUWC) Keyport Range Complex and the Associated Proposed Extensions Study Area § 218.177...

  4. 14 CFR 218.3 - Prohibition against unauthorized operations employing aircraft leased with crew.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... employing aircraft leased with crew. 218.3 Section 218.3 Aeronautics and Space OFFICE OF THE SECRETARY... OTHER FOREIGN PERSON OF AIRCRAFT WITH CREW § 218.3 Prohibition against unauthorized operations employing aircraft leased with crew. (a) No foreign air carrier, or other person not a citizen of the United...

  5. 49 CFR Appendix D to Part 218 - Requirements and Considerations for Implementing Technology Aided Point Protection

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Technology Aided Point Protection D Appendix D to Part 218 Transportation Other Regulations Relating to... PRACTICES Pt. 218, App. D Appendix D to Part 218—Requirements and Considerations for Implementing Technology... exercising the option to provide point protection with the aid of technology as permitted in §...

  6. 49 CFR Appendix D to Part 218 - Requirements and Considerations for Implementing Technology Aided Point Protection

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Technology Aided Point Protection D Appendix D to Part 218 Transportation Other Regulations Relating to... PRACTICES Pt. 218, App. D Appendix D to Part 218—Requirements and Considerations for Implementing Technology... exercising the option to provide point protection with the aid of technology as permitted in §...

  7. 49 CFR Appendix D to Part 218 - Requirements and Considerations for Implementing Technology Aided Point Protection

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Technology Aided Point Protection D Appendix D to Part 218 Transportation Other Regulations Relating to... PRACTICES Pt. 218, App. D Appendix D to Part 218—Requirements and Considerations for Implementing Technology... exercising the option to provide point protection with the aid of technology as permitted in §...

  8. Final Report for research grant "Development of Methods for High Specific Activity Labeling of Biomolecules Using Astatine-211 in Different Oxidation States"

    SciTech Connect

    Wilbur, D., Scott

    2011-12-14

    The overall objective of this research effort was to develop methods for labeling biomolecules with higher oxidation state species of At-211. This was to be done in an effort to develop reagents that had higher in vivo stability than the present carbon-bonded At-211-labeled compounds. We were unsuccessful in that effort, as none of the approaches studied provided reagents that were stable to in vivo deastatination. However, we gained a lot of information about At-211 in higher oxidation states. The studies proved to be very difficult as small changes in pH and other conditions appeared to change the nature of the species that obtained (by HPLC retention time analyses), with many of the species being unidentifiable. The fact that there are no stable isotopes of astatine, and the chemistry of the nearest halogen iodine is quite different, made it very difficult to interpret results of some experiments. With that said, we believe that a lot of valuable information was obtained from the studies. The research effort evaluated: (1) methods for chemical oxidation of At-211, (2) approaches to chelation of oxidized At-211, and (3) approaches to oxidation of astatophenyl compounds. A major hurdle that had to be surmounted to conduct the research was the development of HPLC conditions to separate and identify the various oxidized species formed. Attempts to develop conditions for separation of iodine and astatine species by normal and reversed-phase TLC and ITLC were not successful. However, we were successful in developing conditions (from a large number of attempts) to separate oxidized forms of iodine ([I-125]iodide, [I-125]iodate and [I-125]periodate) and astatine ([At-211]astatide, [At-211]astatate, [At-211]perastatate, and several unidentified At-211 species). Information on the basic oxidation and characterization of At-211 species is provided under Objective 1. Conditions were developed to obtain new At-211 labeling method where At-211 is chelated with the DOTA and

  9. Establishment of radioactive astatine and iodine uptake in cancer cell lines expressing the human sodium/iodide symporter.

    PubMed

    Petrich, T; Helmeke, H-J; Meyer, G J; Knapp, W H; Pötter, E

    2002-07-01

    The sodium/iodide symporter (NIS) has been recognized as an attractive target for radioiodine-mediated cancer gene therapy. In this study we investigated the role of human NIS for cellular uptake of the high LET alpha-emitter astatine-211 ((211)At) in comparison with radioiodine as a potential radionuclide for future applications. A mammalian NIS expression vector was constructed and used to generate six stable NIS-expressing cancer cell lines (three derived from thyroid carcinoma, two from colon carcinoma, one from glioblastoma). Compared with the respective control cell lines, steady state radionuclide uptake of NIS-expressing cell lines increased up to 350-fold for iodine-123 ((123)I), 340-fold for technetium-99m pertechnetate ((99m)TcO(4)(-)) and 60-fold for (211)At. Cellular (211)At accumulation was found to be dependent on extracellular Na(+) ions and displayed a similar sensitivity towards sodium perchlorate inhibition as radioiodide and (99m)TcO(4)(-) uptake. Heterologous competition with unlabelled NaI decreased NIS-mediated (211)At uptake to levels of NIS-negative control cells. Following uptake both radioiodide and (211)At were rapidly (apparent t(1/2) 3-15 min) released by the cells as determined by wash-out experiments. Data of scintigraphic tumour imaging in a xenograft nude mice model of transplanted NIS-modified thyroid cells indicated that radionuclide uptake in NIS-expressing tumours was up to 70 times ((123)I), 25 times ((99m)TcO(4)(-)) and 10 times ((211)At) higher than in control tumours or normal tissues except stomach (3-5 times) and thyroid gland (5-10 times). Thirty-four percent and 14% of the administered activity of (123)I and (211)At, respectively, was found in NIS tumours by region of interest analysis ( n=2). Compared with cell culture experiments, the effective half-life in vivo was greatly prolonged (6.5 h for (123)I, 5.2 h for (211)At) and preliminary dosimetric calculations indicate high tumour absorbed doses (3.5 Gy

  10. The cytotoxicity and microdosimetry of astatine-211-labeled chimeric monoclonal antibodies in human glioma and melanoma cells in vitro.

    PubMed

    Larsen, R H; Akabani, G; Welsh, P; Zalutsky, M R

    1998-02-01

    The cytotoxicity of alpha-particle-emitting endoradiotherapeutic compounds is of increasing interest because clinical evaluation of these potential therapeutic agents is commencing. Astatine-211 is a radionuclide with a 7.2-h half-life that emits 5.87 and 7.45 MeV alpha particles. In the present work, we have investigated the in vitro cytotoxicity of 211At-labeled chimeric monoclonal antibodies (mAbs) in monolayers of D-247 MG human glioma cells and SK-MEL-28 human melanoma cells. The mAbs studied were 81C6, reactive with the extracellular matrix antigen tenascin, Mel-14, directed against the cell membrane antigen proteoglycan chondroitin sulfate, and a nonspecific control mAb, TPS3.2. Cell uptake increased as a function of activity concentration after a 1-h exposure to the 211At-labeled mAbs. The retention of activity was also measured to calculate cumulative activity associated with the cells and the medium. The clonogenic survival as a function of activity concentration was linear in all cases with no detectable shoulder. Microdosimetric analyses were performed based on measured cell geometry, cumulative activity and Monte Carlo transport of alpha particles. Using 18 kBq/ml activity concentration and 1 h of incubation, a two to five times higher activity bound to the microcolonies was found for the specific mAbs compared to the nonspecific mAb. These calculations indicated that a survival fraction of 0.37 was achieved with 0.24-0.28 Gy for D-247 MG cells and 0.27-0.29 Gy for SK-MEL-28 cells. The microdosimetric cell sensitivity, z0, for D-247 MG cells was significantly lower than for SK-MEL-28 cells (0.08 compared to 0.15 Gy). For both cell lines, reduction in survival to 0.37 required an average of only 1-2 alpha-particle hits to the cell nucleus.

  11. Transcriptional response of BALB/c mouse thyroids following in vivo astatine-211 exposure reveals distinct gene expression profiles

    PubMed Central

    2012-01-01

    Background Astatine-211 (211At) is an alpha particle emitting halogen with almost optimal linear energy transfer for creating DNA double-strand breaks and is thus proposed for radionuclide therapy when bound to tumor-seeking agents. Unbound 211At accumulates in the thyroid gland, and the concept of basal radiation-induced biological effects in the thyroid tissue is, to a high degree, unknown and is most valuable. Methods Female BALB/c nude mice were intravenously injected with 0.064 to 42 kBq of 211At, resulting in absorbed doses of 0.05 to 32 Gy in the thyroid gland. Thyroids were removed 24 h after injection; total RNA was extracted from pooled thyroids and processed in triplicate using Illumina MouseRef-8 Whole-Genome Expression Beadchips. Results Thyroids exposed to 211At revealed distinctive gene expression profiles compared to non-irradiated controls. A larger number of genes were affected at low absorbed doses (0.05 and 0.5 Gy) compared to intermediate (1.4 Gy) and higher absorbed doses (11 and 32 Gy). The proportion of dose-specific genes increased with decreased absorbed dose. Additionally, 1.4 Gy often exerted opposite regulation on gene expression compared to the other absorbed doses. Using Gene Ontology data, an immunological effect was detected at 0.05 and 11 Gy. Effects on cellular response to external stress and cell cycle regulation and proliferation were detected at 1.4 and 11 Gy. Conclusions Conclusively, the cellular response to ionizing radiation is complex and differs with absorbed dose. The response acquired at high absorbed doses cannot be extrapolated down to low absorbed doses or vice versa. We also demonstrated that the thyroid - already at absorbed doses similar to those obtained in radionuclide therapy - responds with expression of a high number of genes. Due to the increased heterogeneous irradiation at low absorbed doses, we suggest that this response partly originates from non-irradiated cells in the tissue, i.e., bystander cells

  12. (211)At-labeled agents for alpha-immunotherapy: On the in vivo stability of astatine-agent bonds.

    PubMed

    Ayed, Tahra; Pilmé, Julien; Tézé, David; Bassal, Fadel; Barbet, Jacques; Chérel, Michel; Champion, Julie; Maurice, Rémi; Montavon, Gilles; Galland, Nicolas

    2016-06-30

    The application of (211)At to targeted cancer therapy is currently hindered by the rapid deastatination that occurs in vivo. As the deastatination mechanism is unknown, we tackled this issue from the viewpoint of the intrinsic properties of At-involving chemical bonds. An apparent correlation has been evidenced between in vivo stability of (211)At-labeled compounds and the At-R (R = C, B) bond enthalpies obtained from relativistic quantum mechanical calculations. Furthermore, we highlight important differences in the nature of the At-C and At-B bonds of interest, e.g. the opposite signs of the effective astatine charges, which implies different stabilities with respect to the biological medium. Beyond their practical use for rationalizing the labeling protocols used for (211)At, the proposed computational approach can readily be used to investigate bioactive molecules labeled with other heavy radionuclides.

  13. miR-218 inhibited tumor angiogenesis by targeting ROBO1 in gastric cancer.

    PubMed

    Xiangyuan, Zhang; Jiaqiang, Dong; Yan, He; Ming, Zhao; Zhen, Liu; Na, Wang; Mingzuo, Jiang; Zhe, Zhang; Gang, Liu; Haiming, Liu; Yongzhan, Nie; Daiming, Fan; Jun, Tie

    2017-03-17

    Aberrant expression of miRNAs is involved in several carcinogenic processes, including tumor growth, metastasis and angiogenesis. The aim of this study was to determine the role of miR-218 in gastric cancer angiogenesis. In situ hybridization was performed on a set of tissue microarray samples to assess the difference in miR-218 expression in vessels between tumor tissues and normal gastric mucosa. In vitro, ectopic expression of miR-218 disturbed the tubular structure and inhibited the migration of endothelial cells. Motility and tube formation were rescued when miR-218 was downregulated. Moreover, miR-218 suppressed endothelial cell sprouting in a fibrin bead sprouting assay. Subsequently, we identified ROBO1 as a target of miR-218 in endothelial cells and determined it was responsible for the effect of miR-218 on tumor angiogenesis. In vivo, local injection of mature miR-218 in xenografted tumors disrupted the vessel plexus and thus inhibited tumor growth. Taken together, our study demonstrated an anti-angiogenic role of miR-218 in gastric cancer and indicated that delivery of miR-218 may be a potential therapeutic strategy to inhibit tumor angiogenesis.

  14. ESR study on the antioxidant activity of TAK-218 in biological model membranes.

    PubMed

    Murakami, M; Fukatsu, K; Ohkawa, S; Kasahara, F; Sugawara, T

    2000-06-01

    TAK-218 has a 2,3-dihydrobenzofuran-5-amine (coumaran) structure which resembles alpha-tocopherol, and is a promising candidate as an agent for central nervous system (CNS) trauma and ischemia. The radical scavenging activity of TAK-218 was studied using electron spin resonance (ESR) spectroscopy. TAK-218 exhibited a more potent scavenging activity towards the hydroxyl radical than did the well-known hydroxyl radical scavengers, mannitol and dimethylsulfoxide. Towards the superoxide radical, TAK-218 showed equal potency to glutathione. TAK-218 reacted rapidly with stable radicals, such as galvinoxyl and 2,2-diphenyl-1-picrylhydrazyl hydrate (DPPH), and gave the quinone as a two-electron oxidized product in analogy with alpha-tocopherol. To exhibit an excellent antioxidative activity in living systems, the compounds should not only have the intrinsic radical scavenging activity but also good distribution in the biological lipid-bilayer membrane. To examine the antioxidant activity of TAK-218, the inhibition of lipid peroxidation by alpha-tocopherol and TAK-218 in liposomal membranes was studied using an ESR spin-label technique. Both alpha-tocopherol and TAK-218 completely inhibited lipid peroxidation by radicals generated in an aqueous layer using a water-soluble radical initiator, 2,2'-azobis-(2-amidinopropane) hydrochloride (AAPH). At a high incubation temperature (45 degrees C), alpha-tocopherol scavenged radicals more effectively than TAK-218 on the surface of the membrane, while TAK-218 scavenged radicals more effectively in the interior of the membrane. The difference between TAK-218 and alpha-tocopherol for radical scavenging in the membrane system derives from the different distribution pattern of these compounds. TAK-218 can penetrate the membrane freely and can scavenge the radical in the membrane interior. Furthermore, TAK-218 was shown to inhibit lipid peroxidation initiated by a lipid soluble radical initiator, 2,2'-azobis-(2,4-dimethylvaleronitrile

  15. 24 CFR 884.218 - Reexamination of family income and composition.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Reexamination of family income and composition. 884.218 Section 884.218 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF THE ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER,...

  16. 24 CFR 884.218 - Reexamination of family income and composition.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false Reexamination of family income and composition. 884.218 Section 884.218 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED) OFFICE OF THE ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER,...

  17. 42 CFR 425.218 - Termination of the agreement by CMS.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 3 2012-10-01 2012-10-01 false Termination of the agreement by CMS. 425.218... and Participation Agreement § 425.218 Termination of the agreement by CMS. (a) General. CMS may... termination by CMS. CMS may terminate the participation agreement for reasons including, but not limited...

  18. 42 CFR 425.218 - Termination of the agreement by CMS.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 3 2013-10-01 2013-10-01 false Termination of the agreement by CMS. 425.218... and Participation Agreement § 425.218 Termination of the agreement by CMS. (a) General. CMS may... termination by CMS. CMS may terminate the participation agreement for reasons including, but not limited...

  19. 42 CFR 425.218 - Termination of the agreement by CMS.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 3 2014-10-01 2014-10-01 false Termination of the agreement by CMS. 425.218... and Participation Agreement § 425.218 Termination of the agreement by CMS. (a) General. CMS may... termination by CMS. CMS may terminate the participation agreement for reasons including, but not limited...

  20. 30 CFR 218.520 - What definitions apply to this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What definitions apply to this subpart? 218.520 Section 218.520 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS AND INCENTIVES Service of...

  1. 30 CFR 218.580 - When do I submit Form MMS-4444?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When do I submit Form MMS-4444? 218.580 Section 218.580 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS AND INCENTIVES Service of...

  2. 30 CFR 218.42 - Cross-lease netting in calculation of late-payment interest.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Cross-lease netting in calculation of late-payment interest. 218.42 Section 218.42 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS...

  3. 30 CFR 218.200 - Payment of royalties, rentals, and deferred bonuses.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Payment of royalties, rentals, and deferred bonuses. 218.200 Section 218.200 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS AND INCENTIVES...

  4. 30 CFR 218.500 - What is the purpose of this subpart?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What is the purpose of this subpart? 218.500 Section 218.500 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS AND INCENTIVES Service of...

  5. 30 CFR 218.560 - How do I submit Form MMS-4444?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I submit Form MMS-4444? 218.560 Section 218.560 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS AND INCENTIVES Service of...

  6. 30 CFR 218.52 - How does a lessee designate a Designee?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How does a lessee designate a Designee? 218.52 Section 218.52 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS AND INCENTIVES Oil and Gas,...

  7. 30 CFR 218.303 - May I credit rental towards royalty?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false May I credit rental towards royalty? 218.303 Section 218.303 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT COLLECTION OF MONIES AND PROVISION FOR GEOTHERMAL CREDITS AND INCENTIVES Geothermal...

  8. 24 CFR 884.218 - Reexamination of family income and composition.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Reexamination of family income and composition. 884.218 Section 884.218 Housing and Urban Development Regulations Relating to Housing and Urban... OF HOUSING AND URBAN DEVELOPMENT (SECTION 8 HOUSING ASSISTANCE PROGRAMS, SECTION 202 DIRECT...

  9. 20 CFR 218.35 - When an employee age annuity ends.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true When an employee age annuity ends. 218.35... ANNUITY BEGINNING AND ENDING DATES When an Annuity Ends § 218.35 When an employee age annuity ends. An employee annuity based on age ends with the last day of the month before the month in which the...

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    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true When an employee age annuity ends. 218.35... ANNUITY BEGINNING AND ENDING DATES When an Annuity Ends § 218.35 When an employee age annuity ends. An employee annuity based on age ends with the last day of the month before the month in which the...

  11. 20 CFR 218.35 - When an employee age annuity ends.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false When an employee age annuity ends. 218.35... ANNUITY BEGINNING AND ENDING DATES When an Annuity Ends § 218.35 When an employee age annuity ends. An employee annuity based on age ends with the last day of the month before the month in which the...

  12. 20 CFR 218.35 - When an employee age annuity ends.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false When an employee age annuity ends. 218.35... ANNUITY BEGINNING AND ENDING DATES When an Annuity Ends § 218.35 When an employee age annuity ends. An employee annuity based on age ends with the last day of the month before the month in which the...

  13. 50 CFR 218.128 - Renewal of Letters of Authorization and adaptive management.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 10 2012-10-01 2012-10-01 false Renewal of Letters of Authorization and adaptive management. 218.128 Section 218.128 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE... Letters of Authorization are restricted to: (1) New cited information and data indicating that...

  14. 50 CFR 218.128 - Renewal of Letters of Authorization and adaptive management.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Renewal of Letters of Authorization and adaptive management. 218.128 Section 218.128 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE... comment on renewals of Letters of Authorization are restricted to: (1) New cited information and...

  15. 50 CFR 218.177 - Renewal of Letters of Authorization and adaptive management.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Renewal of Letters of Authorization and adaptive management. 218.177 Section 218.177 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE... cited information and data indicating that the determinations made in this document are in need...

  16. 50 CFR 218.8 - Renewal of Letters of Authorization and adaptive management.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 10 2012-10-01 2012-10-01 false Renewal of Letters of Authorization and adaptive management. 218.8 Section 218.8 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL... to: (1) New cited information and data indicating that the determinations made in this document...

  17. 50 CFR 218.177 - Renewal of Letters of Authorization and adaptive management.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 10 2012-10-01 2012-10-01 false Renewal of Letters of Authorization and adaptive management. 218.177 Section 218.177 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE... Letters of Authorization are restricted to: (1) New cited information and data indicating that...

  18. 50 CFR 218.37 - Renewal of Letters of Authorization and adaptive management.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 10 2012-10-01 2012-10-01 false Renewal of Letters of Authorization and adaptive management. 218.37 Section 218.37 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE... cited information and data indicating that the determinations made in this document are in need...

  19. 50 CFR 218.187 - Renewal of Letters of Authorization and adaptive management.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Renewal of Letters of Authorization and adaptive management. 218.187 Section 218.187 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE... Authorization are restricted to: (1) New cited information and data indicating that the determinations made...

  20. 50 CFR 218.17 - Renewal of Letters of Authorization and adaptive management.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Renewal of Letters of Authorization and adaptive management. 218.17 Section 218.17 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE... to: (1) New cited information and data indicating that the determinations made in this document...