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Sample records for atomnoi energetike xx

  1. Leprechaunism with mosaicism 46, XX/47, XX extra ring chromosome.

    PubMed Central

    Ventruto, V; Sebastio, L; Sebastio, G; DeMasi, R V; Vota, U; Farina, L; Festa, B

    1977-01-01

    A case of leprechaunism with a chromosomal abnormality is reported. The patient was a female infant, born to healthy, consanguineous young parents. Her course was one of extreme marasmus, with death at 3 months of age. She presented the classical features of the syndrome and chromosome mosaicism 46, XX/47, XX, +r(?). It was not possible to identify the origin of the extra ring chromosome. It is difficult to establish the role of such a cytogenetic finding in the aetiology of the syndrome. Images PMID:592357

  2. XX Pyxidis: the Mummy returns

    NASA Astrophysics Data System (ADS)

    Handler, G.

    2002-02-01

    An overview of the work devoted to the delta Sct star XX Pyx within this Flanders-South Africa bilateral programme is given. We first review the motivations for investigating this object in detail, and we explain its importance for asteroseismology of delta Sct stars in general. We continue by pointing out the public availability of the time series photometric data of the star through a FLANSA collaboration, and then look back on the finding that XX Pyx is actually located in a binary system. Finally, we briefly discuss the evidence for anomalous cycles occurring in the star's light curves and we finish by summarizing what we have learned from the star and what may still be done in the future.

  3. 49 CFR 1242.84 - Marketing, sales, and public relations and advertising (accounts XX-63-88, XX-63-89 and XX-63-93).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Marketing, sales, and public relations and advertising (accounts XX-63-88, XX-63-89 and XX-63-93). 1242.84 Section 1242.84 Transportation Other... advertising (accounts XX-63-88, XX-63-89 and XX-63-93). Separate each common expense account on the basis...

  4. 49 CFR 1242.30 - Dismantling retired road property and depreciation (accounts XX-17-39, XX-18-39, XX-19-39, 62-17...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Dismantling retired road property and depreciation (accounts XX-17-39, XX-18-39, XX-19-39, 62-17-00, 62-18-00, and 62-19-00). 1242.30 Section 1242.30....30 Dismantling retired road property and depreciation (accounts XX-17-39, XX-18-39, XX-19-39,...

  5. 49 CFR 1242.55 - Administration (account XX-51-01).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Trains (XX-51-58) Operating Signals and Interlockers (XX-51-59) Operating Drawbridges (XX-51-60) Highway...) Electric Power Purchased/Produced for Motive Power (XX-51-68) Servicing Locomotives (XX-51-69)...

  6. Prenatal diagnosis of 45,X/46,XX

    SciTech Connect

    Hsu, L.Y.F.

    1996-03-01

    I read with great interest the paper on {open_quotes}Prenatal Diagnosis of 45,X/46,XX mosaicism and 45,X: Implications for Postnatal Outcome{close_quotes} by Koeberl et al. They reported their experience with 12 prenatally diagnosed cases of 45,X/46,XX mosaicism and made a clinical comparison between those 12 cases and their own 41 postnatally diagnosed cases of 45,X/46,XX mosaicism. As expected, they found an overall milder phenotypic manifestation in the prenatal cases than in the postnatal ones. These authors report a lack of previous prognostic information on this type of prenatally diagnosis of mosaicism and offer their findings to fill this need. However, considerable information on this topic has been published. There have been >200 prenatally diagnosed cases of 45,X/46,XX. According to my data on 189 cases with a prenatal diagnosis of 45,X/46,XX mosaicism (Hsu 1992), there are 114 cases with available information on phenotypic outcome. Of these, 12 (10.5%) were reported to have some features of Turner syndrome, 4 had other anomalies probably not related to Turner syndrome, and 2 resulted in stillbirth. The overall rate for an abnormal phenotype in this category was thus 16/114 (14.03%). However, we must realize that, even in patients with a nonmosaic 45,X complement, the major features of Turner syndrome, such as short stature and sexual infantilism, are manifested only later in childhood or in adolescence. 3 refs.

  7. Genetics Home Reference: 46,XX testicular disorder of sex development

    MedlinePlus

    ... of sex development 46,XX testicular disorder of sex development Enable Javascript to view the expand/collapse ... Close All Description 46,XX testicular disorder of sex development is a condition in which individuals with ...

  8. 49 CFR 1242.56 - Engine crews and train crews (accounts XX-51-56 and XX-51-57).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Engine crews and train crews (accounts XX-51-56 and XX-51-57). 1242.56 Section 1242.56 Transportation Other Regulations Relating to Transportation... RAILROADS 1 Operating Expenses-Transportation § 1242.56 Engine crews and train crews (accounts XX-51-56...

  9. 9xx high power pump modules

    NASA Astrophysics Data System (ADS)

    Pawlik, Susanne; Sverdlov, Boris; Bättig, Rainer; Schmidt, Berthold; Pfeiffer, Hans-Ulrich; Arlt, Sebastian; Lichtenstein, Norbert; Müller, Jürgen; Troger, Jörg; Valk, Bernd; Harder, Christoph

    2006-02-01

    In this communication we present the characteristics of Bookham's MU7-9xx-01 laser module with multimode fiber output. This latest generation of our multimode modules is designed for light output power of up to 7 W in uncooled operation in the wavelength range between 915 nm and 975 nm. The key element of the module is our new SES8-9xx-01 broad area single emitter. These high power lasers in the 9xx nm wavelength range show a high slope efficiency of up to 1.2 W/A in CW room temperature operation. High efficiency combined with low threshold current and low operation voltage result in a maximum wall plug efficiency of above 65%. Almost 4000 h lifetest data at accelerated conditions are available for the laser diodes. The data give estimated reliability values of below 5 kFIT at operating conditions (between 8 A and 8.5 A injection current at up to 35°C heat sink temperature). The robustness of the new lasers is also illustrated by the fact that no catastrophic mirror damage was observed up to 22.5 W of light output power. The low divergence of the laser beam allows coupling into multimode fiber with 0.15 or 0.22 numerical aperture (NA) with a coupling efficiency above 90% at operation condition. Maximum ex-fiber light output powers of 11.5 W are shown. On module level around 2000 h lifetest data are accumulated without any failure or sign of degradation.

  10. Modified 43XX Steels for High Toughness

    DTIC Science & Technology

    1980-04-01

    AL AMMRC TR 80-20 MODIFIED 43XX STEELS FOR HIGH TOUGHNESS T CS.,•, °x ,•, o o,,o,,,sD T I W4 AftELECTE APRIL 1980 J N.J. Kar, V.F. Zackay and E.R...carried out. Isohra tasomions in these steels resulted inn bbaainni 11-v DI FOR Z 47 RITIOW OF I NOV695 IS OBSOLETE UCASFE SECURITY UCLASSIFIEDINOFTI PAGE...this investigation for Si-modified AISI 4330 steel appear to be superior to those for unmodified AISI 4340 and 300-M steels , whilst the strength-tough

  11. [XX 'pure' gonadal dysgenesis and XYY syndrome].

    PubMed

    Itoh, Naoki; Tsukamoto, Taiji

    2004-02-01

    XX 'pure' gonadal dysgenesis is a disease related to Turner's syndrome. Patients of this disease are characterized by normal female external genitalia, bilateral streak gonads, amenorrhea and sexual infantilism. Recently, it has been reported that point mutations of the FSH receptor gene may be one of cause of this disease. The relationship between criminal behavior and XYY syndrome is still controversial. Increased incidence of disomic sperm in 47,XYY males has been reported by fluorescent in situ hybridization(FISH). Genetic counseling should be done when they undergo intracytoplasmic sperm injection.

  12. Classification of the Enigmatic Variable XX Sct

    NASA Astrophysics Data System (ADS)

    Bonjorni, J.; Samus, N. N.

    1999-12-01

    The irregular variable XX Sct has been ascribed five different variability types since its discovery in 1924, from a Cepheid to a rapid irregular variable. Surprisingly, this 13m star has virtually no mention in recent literature, though its classification is still a mystery. We sought to resolve this puzzle by a careful reexamination of nearly 1200 blue photographic plates of this star at the Maria Mitchell Observatory. These revealed strong irregular variability of up to 2 magnitudes on different time scales, including Algol-like minima with a timescale of 10 days or less. Several possible periods have been found, none of which are particularly convincing. UBV photometry and a low-resolution optical spectrum are consistent with a reddened A star. We tentatively suggest that XX Sct is one of the class of young, intermediate mass Herbig Ae/Be stars known as UXors. Further examination of these data is needed to confirm this classification. This project was supported by the NSF/REU grant AST-9820555.

  13. 49 CFR 1242.36 - Machinery repair and equipment damaged (accounts XX-26-40 and XX-26-48).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Machinery repair and equipment damaged (accounts XX-26-40 and XX-26-48). 1242.36 Section 1242.36 Transportation Other Regulations Relating to... FOR RAILROADS 1 Operating Expenses-Equipment § 1242.36 Machinery repair and equipment...

  14. 49 CFR 1242.56 - Engine crews and train crews (accounts XX-51-56 and XX-51-57).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Engine crews and train crews (accounts XX-51-56 and XX-51-57). 1242.56 Section 1242.56 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) ACCOUNTS, RECORDS...

  15. 49 CFR 1242.19 - Electric power systems (account XX-19-21).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Electric power systems (account XX-19-21). 1242.19... Structures § 1242.19 Electric power systems (account XX-19-21). Separate common expenses on basis of common expenses of electric power purchased or produced for motive power (accounts XX-51-68 and XX-52-68)....

  16. 49 CFR 1242.19 - Electric power systems (account XX-19-21).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Electric power systems (account XX-19-21). 1242.19... Structures § 1242.19 Electric power systems (account XX-19-21). Separate common expenses on basis of common expenses of electric power purchased or produced for motive power (accounts XX-51-68 and XX-52-68)....

  17. 49 CFR 1242.19 - Electric power systems (account XX-19-21).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Electric power systems (account XX-19-21). 1242.19... Structures § 1242.19 Electric power systems (account XX-19-21). Separate common expenses on basis of common expenses of electric power purchased or produced for motive power (accounts XX-51-68 and XX-52-68)....

  18. 49 CFR 1242.19 - Electric power systems (account XX-19-21).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 9 2013-10-01 2013-10-01 false Electric power systems (account XX-19-21). 1242.19... Structures § 1242.19 Electric power systems (account XX-19-21). Separate common expenses on basis of common expenses of electric power purchased or produced for motive power (accounts XX-51-68 and XX-52-68)....

  19. 49 CFR 1242.19 - Electric power systems (account XX-19-21).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Electric power systems (account XX-19-21). 1242.19... Structures § 1242.19 Electric power systems (account XX-19-21). Separate common expenses on basis of common expenses of electric power purchased or produced for motive power (accounts XX-51-68 and XX-52-68)....

  20. The genetics of XX gonadal dysgenesis

    SciTech Connect

    Aittomaeki, K. )

    1994-05-01

    In a nationwide population-based study of women born between 1950 and 1976, 75 patients with XX gonadal dysgenesis (XXGD) were identified in Finland. Patients were ascertained through hospital records and the registers of chromosome laboratories. In one family 4 daughters were affected; in six families 2 daughters were affected; and 57 cases were isolated. In one additional family the two affected females were in successive generations. Population records were utilized to trace ancestors of patients back to the beginning of the 19th century, in most cases. Consanguinity was detected in 8 (12%) of 66 families. When females only are considered, the segregation analyses yield a proportion of .23 affected. The relatively large number of affected individuals identified (incidence 1 in 8,300 live-born girls) implies a high gene frequency in the Finnish population. The geographic distribution was highly uneven, with most families originating in the sparsely populated north-central part of Finland. These findings support the existence of an autosomal recessive (XXGD) gene (locus designation [open quotes]ODG1[close quotes]) that is highly enriched in Finland. The multiplex families already identified will make it possible to map the ODG1 gene by a random search for linkage by using polymorphic markers. Linkage-disequilibrium analysis in the sporadic patients will then be used to test for genetic homogeneity versus heterogeneity. 27 refs., 3 figs.

  1. [Enteroviruses in the XX and XXI centuries].

    PubMed

    Seĭbil', V B; Malyshkina, L P

    2005-01-01

    The modern view of the role of enteroviruses in the eradication of poliomyelitis is presented. Enteroviruses were discovered in the XX century. In the 1950s they caused great epidemics of poliomyelitis and serous meningitis in many countries of the world. The introduction of oral poliomyelitis vaccine (OPV) into medical practice made it possible to eliminate the epidemics of poliomyelitis in a short time. Poliomyelitis morbidity was reduced to sporadic cases and in a number of regions disappeared. OPV produced non-specific influence also on the epidemics of serous meningitis, as well as on a case incidence. The eradication of poliomyelitis viruses and the cessation of immunization with OPV will not result in eradication of paralytic diseases. Paralytogenic viruses of 20 serotypes circulate in nature, and some of these viruses are capable of causing the outbreaks of severe paralytic diseases. The authors propose either to retain immunization with OVP as tour immunizations with monovaccine of type 2, or to create new live enterovirus vaccines on the basis of avirulent enterovirus strains.

  2. A healthy, female chimera with 46,XX/46,XY karyotype.

    PubMed

    Binkhorst, Mathijs; de Leeuw, Nicole; Otten, Barto J

    2009-01-01

    We report a healthy and unambiguously female newborn, whose phenotypic sex contradicted the expected male sex based on previously performed prenatal cytogenetic analysis. Both 46,XX and 46,XY cells were detected in a villus sample, the former having been attributed to maternal cell contamination. Postnatal karyotyping in peripheral lymphocytes confirmed the presence of two cell lines, one 46,XX (70%) and one 46,XY (30%). After exclusion of alternative explanations for the observed genotype, a diagnosis of chimerism was made. Chimeras containing cell lines of opposite sex usually feature ovotesticular development with associated genital ambiguity. To account for the normal female appearance of our patient, we postulate the exclusive involvement of 46,XX cells in gonad formation.

  3. Ambiguous genitalia in XX male children: report of two infants.

    PubMed

    Roe, T F; Alfi, O S

    1977-07-01

    Two infants with ambiguous genitalia were recognized to have the XX male syndrome. Although most XX males have normal penile development, a review of the reported cases showed that eight of the 14 affected children, diagnosed before age 15 years, had penile abnormalities, most commonly hypospadias and/or chordee. This syndrome should be considered in children with incomplete genital differentiation. The available indirect evidence suggests that deficient testosterone production by the fetal testes accounts for the genital ambiguity. Although no explanation has been established for the presence of testes in the apparent absence of the Y chromosome, studies of the X-linked Xg blood group in XX males demonstrate a high frequency of unusual inheritance patterns. This implies that the abnormality in the transmission of maleness in affected families may also be X-related rather than autosomal.

  4. 76 FR 57767 - Proposed Generic Communication; Draft NRC Generic Letter 2011-XX: Seismic Risk Evaluations for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-16

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Proposed Generic Communication; Draft NRC Generic Letter 2011-XX: Seismic Risk Evaluations for... NRC Generic Letter 2011- XX: Seismic Risk Evaluations for Operating Reactors. This action is...

  5. 49 CFR 1242.14 - Administration-other (account XX-19-06).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Structures § 1242.14 Administration—other (account XX-19-06). Separate common administration—other expenses... accounts are separated between freight and passenger services: Administration: Track (XX-19-02) Bridges...

  6. 49 CFR 1242.14 - Administration-other (account XX-19-06).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Structures § 1242.14 Administration—other (account XX-19-06). Separate common administration—other expenses... accounts are separated between freight and passenger services: Administration: Track (XX-19-02) Bridges...

  7. 49 CFR 1242.14 - Administration-other (account XX-19-06).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Structures § 1242.14 Administration—other (account XX-19-06). Separate common administration—other expenses... accounts are separated between freight and passenger services: Administration: Track (XX-19-02) Bridges...

  8. 29. Coke oven byproduct building "XX" with ammonia stills; powerhouse ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    29. Coke oven by-product building "XX" with ammonia stills; powerhouse with 8 sisters (stacks) in background; conveyor #20 (with break) on right, pulevrized coal storage bunker on left. Looking north/northwest - Rouge Steel Company, 3001 Miller Road, Dearborn, MI

  9. 30. XX byproducts building (containing coke gas compressors at north ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    30. XX by-products building (containing coke gas compressors at north end, ammonia stills in south end), #20 coal conveyor jutting out of top on east side, continuing out west side to bunker. Looking south/southeast - Rouge Steel Company, 3001 Miller Road, Dearborn, MI

  10. Using Title XX to Serve Children and Youth.

    ERIC Educational Resources Information Center

    Twiname, John D.; And Others

    With the passage in early 1975 of the social service amendments to the Social Security Act, referred to as Title XX, a major new opportunity to serve children and youth has emerged. Seizing the opportunity will be largely dependent on the well-prepared presentation of a case for the needs of young people by dedicated advocates in every state.…

  11. 49 CFR 1242.66 - Administration (account XX-52-01).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... OPERATING EXPENSES BETWEEN FREIGHT SERVICE AND PASSENGER SERVICE FOR RAILROADS 1 Operating Expenses... common expenses in the following accounts: Switch Cews (XX-52-64) Controlling Operations (XX-52-65) Yard and Terminal Clerical (XX-52-66) Operating Switches, Signals, Retarders and Humps...

  12. 49 CFR 1242.66 - Administration (account XX-52-01).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... OPERATING EXPENSES BETWEEN FREIGHT SERVICE AND PASSENGER SERVICE FOR RAILROADS 1 Operating Expenses... common expenses in the following accounts: Switch Cews (XX-52-64) Controlling Operations (XX-52-65) Yard and Terminal Clerical (XX-52-66) Operating Switches, Signals, Retarders and Humps...

  13. 8- to 13-micron spectroscopy of Comet Levy 1990 XX

    NASA Technical Reports Server (NTRS)

    Lynch, David K.; Russell, Ray W.; Hackwell, John A.; Hanner, Martha S.; Hammel, Heidi B.

    1992-01-01

    The results are reported of IR spectroscopy of Comet Levy 1990 XX over a three-day period when the comet was about 1.54 AU from the sun roughly 70 days before perihelion. Comet Levy 1990 XX was bright, and for at least part of its inbound journey toward perihelion, active. At a distance of 1.54 AU from the sun it showed strong structured silicate emission with peaks or shoulders at 9.8 and 11.2 microns. These features resemble those of Comets P/Halley and Bradfield 1987 XXIX. The comet was variable in brightness. Specifically, the contrast of the silicate features changed by a factor of two relative to the continuum level and showed some evidence for a shape change as well.

  14. 49 CFR 1242.28 - Roadway machines, small tools and supplies, and snow removal (accounts XX-19-36 to XX-19-38...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Roadway machines, small tools and supplies, and snow removal (accounts XX-19-36 to XX-19-38, inclusive). 1242.28 Section 1242.28 Transportation Other... PASSENGER SERVICE FOR RAILROADS 1 Operating Expenses-Way and Structures § 1242.28 Roadway machines,...

  15. 49 CFR 1242.28 - Roadway machines, small tools and supplies, and snow removal (accounts XX-19-36 to XX-19-38...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Roadway machines, small tools and supplies, and snow removal (accounts XX-19-36 to XX-19-38, inclusive). 1242.28 Section 1242.28 Transportation Other... PASSENGER SERVICE FOR RAILROADS 1 Operating Expenses-Way and Structures § 1242.28 Roadway machines,...

  16. 49 CFR 1242.28 - Roadway machines, small tools and supplies, and snow removal (accounts XX-19-36 to XX-19-38...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Roadway machines, small tools and supplies, and snow removal (accounts XX-19-36 to XX-19-38, inclusive). 1242.28 Section 1242.28 Transportation Other... PASSENGER SERVICE FOR RAILROADS 1 Operating Expenses-Way and Structures § 1242.28 Roadway machines,...

  17. 49 CFR 1242.28 - Roadway machines, small tools and supplies, and snow removal (accounts XX-19-36 to XX-19-38...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 9 2013-10-01 2013-10-01 false Roadway machines, small tools and supplies, and snow removal (accounts XX-19-36 to XX-19-38, inclusive). 1242.28 Section 1242.28 Transportation Other... PASSENGER SERVICE FOR RAILROADS 1 Operating Expenses-Way and Structures § 1242.28 Roadway machines,...

  18. 49 CFR 1242.28 - Roadway machines, small tools and supplies, and snow removal (accounts XX-19-36 to XX-19-38...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Roadway machines, small tools and supplies, and snow removal (accounts XX-19-36 to XX-19-38, inclusive). 1242.28 Section 1242.28 Transportation Other... PASSENGER SERVICE FOR RAILROADS 1 Operating Expenses-Way and Structures § 1242.28 Roadway machines,...

  19. Services Officer Utilization Field (AFS 62XX and Equivalent-Grade Civilians).

    DTIC Science & Technology

    1986-06-01

    CHART le~ -- Sq ,.. O. pt’*. q UNITED STATES AIR FORCE cv, Lfl o D SERVICES OFFICER UTILIZATION FIELD (AFS 62XX AND EQUIVALENT-GRADE CIVILLANS) AFPT 90...Administration From January through Ma’ch 1985, job inventories were administered to all elicible AFSC 62XX nfficer: in the continental United States ... PUBLIC RELEASE: DISTRIBUTION UNLIMITED t, , . . . .. .. . . . . , . . . . . . , . _". ... , I! . . $ IJSTRIBIJTION FOR AFS( u-)XX OSR AND SUPPORTING

  20. 49 CFR 1242.10 - Administration-track (account XX-19-02).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... accounts are separated between freight and passenger services: Roadway: Running (XX-17-10) Switching (XX-18-10) Ties: Running (21-17-13) Switching (21-18-13) Rails: Running (21-17-14) Switching (21-18-14) Other Track Materials: Running (21-17-15) Switching (21-18-15) Ballast: Running (21-17-16) Switching...

  1. 49 CFR 1242.12 - Administration-signals (account XX-19-04).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Administration-signals (account XX-19-04). 1242.12... Structures § 1242.12 Administration—signals (account XX-19-04). Separate common administration—signals expenses between freight and passenger services in the same proportion as the common expenses of...

  2. 49 CFR 1242.26 - Miscellaneous building and structures (account XX-19-28).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... XX-19-28). Separate common expenses as specific facts indicate or according to distribution of common expenses listed in § 1242.10, Administration-Track (account XX-19-02). ...-19-28). 1242.26 Section 1242.26 Transportation Other Regulations Relating to...

  3. 49 CFR 1242.13 - Administration-communica- tions (account XX-19-05).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Administration-communica- tions (account XX-19-05... Structures § 1242.13 Administration—communica- tions (account XX-19-05). Separate common administration—communications expenses between freight and passenger services in the same proportion as the common expenses...

  4. 49 CFR 1242.23 - Shop buildings-freight cars (account XX-13-25).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 9 2013-10-01 2013-10-01 false Shop buildings-freight cars (account XX-13-25). 1242.23 Section 1242.23 Transportation Other Regulations Relating to Transportation (Continued) SURFACE... Structures § 1242.23 Shop buildings—freight cars (account XX-13-25). These accounts pertain solely to...

  5. 49 CFR 1242.49 - Equipment damaged (account XX-27-48).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Equipment damaged (account XX-27-48). 1242.49...-Equipment § 1242.49 Equipment damaged (account XX-27-48). Separate common expenses according to distribution of common expenses in machinery, passenger and other revenue equipment, computer and data...

  6. 49 CFR 1242.25 - Locomotive servicing facilities (account XX-19-27).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Locomotive servicing facilities (account XX-19-27). 1242.25 Section 1242.25 Transportation Other Regulations Relating to Transportation (Continued) SURFACE... Structures § 1242.25 Locomotive servicing facilities (account XX-19-27). Separate common expenses...

  7. 49 CFR 1242.24 - Shop buildings-other equipment (account XX-19-26).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Shop buildings-other equipment (account XX-19-26). 1242.24 Section 1242.24 Transportation Other Regulations Relating to Transportation (Continued) SURFACE... Structures § 1242.24 Shop buildings—other equipment (account XX-19-26). Assign directly to freight (or...

  8. 49 CFR 1242.59 - Train inspection and lubrication (account XX-51-62).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Train inspection and lubrication (account XX-51-62). 1242.59 Section 1242.59 Transportation Other Regulations Relating to Transportation (Continued) SURFACE...-Transportation § 1242.59 Train inspection and lubrication (account XX-51-62). Separate common expenses on...

  9. 49 CFR 1242.10 - Administration-track (account XX-19-02).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... accounts are separated between freight and passenger services: Roadway: Running (XX-17-10) Switching (XX-18-10) Ties: Running (21-17-13) Switching (21-18-13) Rails: Running (21-17-14) Switching (21-18-14) Other Track Materials: Running (21-17-15) Switching (21-18-15) Ballast: Running (21-17-16) Switching...

  10. First Annual Report to Congress on Title XX of the Social Security Act.

    ERIC Educational Resources Information Center

    Department of Health, Education, and Welfare, Washington, DC.

    This annual report to Congress on Title XX of the Social Security Act reports on the operation of the 1976 fiscal year program. Preceding the report are descriptive highlights of the program. Title XX of the Social Security Act changes the role and relationships of the Department of Health, Education, and Welfare; the individual states; and…

  11. 49 CFR 1242.23 - Shop buildings-freight cars (account XX-13-25).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Shop buildings-freight cars (account XX-13-25). 1242.23 Section 1242.23 Transportation Other Regulations Relating to Transportation (Continued) SURFACE... Structures § 1242.23 Shop buildings—freight cars (account XX-13-25). These accounts pertain solely to...

  12. 49 CFR 1242.23 - Shop buildings-freight cars (account XX-13-25).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Shop buildings-freight cars (account XX-13-25). 1242.23 Section 1242.23 Transportation Other Regulations Relating to Transportation (Continued) SURFACE... Structures § 1242.23 Shop buildings—freight cars (account XX-13-25). These accounts pertain solely to...

  13. 49 CFR 1242.23 - Shop buildings-freight cars (account XX-13-25).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Shop buildings-freight cars (account XX-13-25). 1242.23 Section 1242.23 Transportation Other Regulations Relating to Transportation (Continued) SURFACE... Structures § 1242.23 Shop buildings—freight cars (account XX-13-25). These accounts pertain solely to...

  14. 49 CFR 1242.23 - Shop buildings-freight cars (account XX-13-25).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Shop buildings-freight cars (account XX-13-25). 1242.23 Section 1242.23 Transportation Other Regulations Relating to Transportation (Continued) SURFACE... Structures § 1242.23 Shop buildings—freight cars (account XX-13-25). These accounts pertain solely to...

  15. 49 CFR 1242.22 - Shop buildings-locomotives (account XX-19-24).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Shop buildings-locomotives (account XX-19-24). 1242.22 Section 1242.22 Transportation Other Regulations Relating to Transportation (Continued) SURFACE... Structures § 1242.22 Shop buildings—locomotives (account XX-19-24). Separate common expenses according...

  16. 49 CFR 1242.22 - Shop buildings-locomotives (account XX-19-24).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Shop buildings-locomotives (account XX-19-24). 1242.22 Section 1242.22 Transportation Other Regulations Relating to Transportation (Continued) SURFACE... Structures § 1242.22 Shop buildings—locomotives (account XX-19-24). Separate common expenses according...

  17. 49 CFR 1242.57 - Dispatching trains (account XX-51-58).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Dispatching trains (account XX-51-58). 1242.57 Section 1242.57 Transportation Other Regulations Relating to Transportation (Continued) SURFACE...-Transportation § 1242.57 Dispatching trains (account XX-51-58). Separate common expenses on the basis of...

  18. 49 CFR 1242.57 - Dispatching trains (account XX-51-58).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 9 2013-10-01 2013-10-01 false Dispatching trains (account XX-51-58). 1242.57 Section 1242.57 Transportation Other Regulations Relating to Transportation (Continued) SURFACE...-Transportation § 1242.57 Dispatching trains (account XX-51-58). Separate common expenses on the basis of...

  19. 49 CFR 1242.57 - Dispatching trains (account XX-51-58).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Dispatching trains (account XX-51-58). 1242.57 Section 1242.57 Transportation Other Regulations Relating to Transportation (Continued) SURFACE...-Transportation § 1242.57 Dispatching trains (account XX-51-58). Separate common expenses on the basis of...

  20. 49 CFR 1242.57 - Dispatching trains (account XX-51-58).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Dispatching trains (account XX-51-58). 1242.57 Section 1242.57 Transportation Other Regulations Relating to Transportation (Continued) SURFACE...-Transportation § 1242.57 Dispatching trains (account XX-51-58). Separate common expenses on the basis of...

  1. 49 CFR 1242.86 - Industrial development (account XX-61-90).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Industrial development (account XX-61-90). 1242.86 Section 1242.86 Transportation Other Regulations Relating to Transportation (Continued) SURFACE....86 Industrial development (account XX-61-90). These accounts pertain solely to freight service...

  2. 49 CFR 1242.86 - Industrial development (account XX-61-90).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Industrial development (account XX-61-90). 1242.86 Section 1242.86 Transportation Other Regulations Relating to Transportation (Continued) SURFACE....86 Industrial development (account XX-61-90). These accounts pertain solely to freight service...

  3. Next generation 9xx/10xx nm high power laser diode bars for multi-kilowatt industrial applications

    NASA Astrophysics Data System (ADS)

    Commin, Paul; Todt, René; Krejci, Martin; Bättig, Rainer; Brunner, Reinhard; Lichtenstein, Norbert

    2013-02-01

    We report on the development of high power, 9xx-10xx nm laser diode bars for use in direct diode systems and for solidstate and fibre laser pumping with applications in industrial markets. For 1 cm wide bars on micro channel cooler (MCC) we have achieved a reliable output power of 250 W across the 900 nm - 1060 nm range. At this output power level we have achieved power conversion efficiencies of 65-66 % and 90 % power content slow axis beam divergence of ~6.5°. Results of a 6400 h life test show an average power degradation of 0.6 % per 1000 h at this operating power level. We will also show results of high power bars assembled on the new OCLARO conductive cooler, the BLM. This new cooler has a small footprint of 12.6 mm × 24.8 mm and is designed for lateral or vertical stacking of diodes in multi kilowatt systems but with the benefits associated with a conductive cooler. The thermal properties are shown to be the same as for a standard CS mount. 1 cm wide high fill factor bars and 0.5 cm wide low fill factor half bars assembled on the BLM operate at 63-64 % power conversion efficiency (PCE) with output powers of up to 250 W and 150 W, respectively.

  4. Two males with SRY-positive 46,XX testicular disorder of sex development.

    PubMed

    Gunes, Sezgin; Asci, Ramazan; Okten, Gülsen; Atac, Fatih; Onat, Onur E; Ogur, Gonul; Aydin, Oguz; Ozcelik, Tayfun; Bagci, Hasan

    2013-02-01

    The 46,XX testicular disorder of sex development (46,XX testicular DSD) is a rare phenotype associated with disorder of the sex chromosomes. We describe the clinical, molecular, and cytogenetic findings of a 16- and a 30-year-old male patient with sex-determining region Y (SRY)-positive 46,XX testicular DSD. Chromosomal analysis revealed 46,XX karyotype. Fluorescence in situ hybridization (FISH) showed the SRY region translocated to the short arm of the X chromosome. The presence of the SRY gene was also confirmed by polymerase chain reaction (PCR). The X chromosome inactivation (XCI) assay showed that both patients have a random pattern of X chromosome inactivation. This report compares the symptoms and features of the SRY-positive 46,XX testicular DSD patients.

  5. The chemical composition of R Coronae Borealis and XX Camelopardalis

    NASA Astrophysics Data System (ADS)

    Cottrell, P. L.; Lambert, D. L.

    1982-10-01

    The R Coronae Borealis stars R CrB and XX Cam are examined using extensive high-resolution Reticon data. Effective temperatures, values of log g, microturbulent velocities, and C/He values are determined, along with elemental abundances and abundance ratios for a wide range of species, including the light and heavy s-process elements. Helium- and carbon-rich models are employed, as is an appropriate model atmosphere code. The evolutionary history of R CrB stars is discussed in detail. It is concluded that both CNO cycle and 3-alpha processed material must have been mixed into the observable layers. The He core and He shell flashes are suggested as possible triggers for the mixing and for the extensive mass loss required to expose the heavily processed layers.

  6. Performance and reliability of high power 7xx nm laser diodes

    NASA Astrophysics Data System (ADS)

    Bao, Ling; Wang, Jun; Devito, Mark; Xu, Dapeng; Grimshaw, Mike; Dong, Weimin; Guan, Xingguo; Huang, Hua; Leisher, Paul; Zhang, Shiguo; Wise, Damian; Martinsen, Robert; Haden, Jim

    2011-02-01

    High power diode lasers in 7xx-nm region, have been needed for various applications. Compared to 9xx nm lasers that have been developed extensively in the last 20 years, high power lasers at 7xx-nm region presents much more challenges for operation power, efficiency, temperature performance and reliability. This paper will present recent progresses on 7xx nm laser diodes for the above attributes. Two laser designs will be reviewed and high power diode laser performance and reliability will be presented. Single emitter devices, with 200μm wide emitting width, show up to 10W reliable operation power, with peak efficiency more than 65%. Accelerated life testing at 12A, 50°C heatsink temperature has been running for thousands of hours. High temperature performance and high COMD threshold (> 20W) will also be shown. Life-test failure modes will also be discussed. In summary, with advanced epitaxial structure design and MOCVD process, critical facet passivation and advanced heatsink and bonding technology, 7xx-8xx nm devices have been demonstrated with high performance and reliability similar to those of 9xx nm devices.

  7. Differential lactate and cholesterol synthetic activities in XY and XX Sertoli cells

    PubMed Central

    Shishido, Yurina; Baba, Takashi; Sato, Tetsuya; Shima, Yuichi; Miyabayashi, Kanako; Inoue, Miki; Akiyama, Haruhiko; Kimura, Hiroshi; Kanai, Yoshiakira; Ishihara, Yasuhiro; Haraguchi, Shogo; Miyazaki, Akira; Rozman, Damjana; Yamazaki, Takeshi; Choi, Man-Ho; Ohkawa, Yasuyuki; Suyama, Mikita; Morohashi, Ken-ichirou

    2017-01-01

    SRY, a sex-determining gene, induces testis development in chromosomally female (XX) individuals. However, mouse XX Sertoli cells carrying Sry (XX/Sry Sertoli cells) are incapable of fully supporting germ cell development, even when the karyotype of the germ cells is XY. While it has therefore been assumed that XX/Sry Sertoli cells are not functionally equivalent to XY Sertoli cells, it has remained unclear which specific functions are affected. To elucidate the functional difference, we compared the gene expression of XY and XX/Sry Sertoli cells. Lactate and cholesterol metabolisms, essential for nursing the developing germ cells, were down-regulated in XX/Sry cells, which appears to be caused at least in part by the differential expression of histone modification enzymes SMCX/SMCY (H3K4me3 demethylase) and UTX/UTY (H3K27me3 demethylase) encoded by the sex chromosomes. We suggest that down-regulation of lactate and cholesterol metabolism that may be due to altered epigenetic modification affects the nursing functions of XX/Sry Sertoli cells. PMID:28150810

  8. 49 CFR 1242.74 - Adjusting and transferring loads, and car loading devices and grain doors (accounts XX-33-71 and...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Adjusting and transferring loads, and car loading devices and grain doors (accounts XX-33-71 and XX-33-72). 1242.74 Section 1242.74 Transportation Other... loads, and car loading devices and grain doors (accounts XX-33-71 and XX-33-72). These accounts...

  9. 49 CFR 1242.74 - Adjusting and transferring loads, and car loading devices and grain doors (accounts XX-33-71 and...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Adjusting and transferring loads, and car loading devices and grain doors (accounts XX-33-71 and XX-33-72). 1242.74 Section 1242.74 Transportation Other... loads, and car loading devices and grain doors (accounts XX-33-71 and XX-33-72). These accounts...

  10. 49 CFR 1242.18 - Communication systems (account XX-19-20).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Structures § 1242.18 Communication systems (account XX-19-20). Separate common expenses on the basis of the common expense separation in: Way and Structures—Administration—Track, Bridges and Culverts, and...

  11. 49 CFR 1242.18 - Communication systems (account XX-19-20).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Structures § 1242.18 Communication systems (account XX-19-20). Separate common expenses on the basis of the common expense separation in: Way and Structures—Administration—Track, Bridges and Culverts, and...

  12. 49 CFR 1242.18 - Communication systems (account XX-19-20).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Structures § 1242.18 Communication systems (account XX-19-20). Separate common expenses on the basis of the common expense separation in: Way and Structures—Administration—Track, Bridges and Culverts, and...

  13. Isodicentric Y Mosaicism Involving a 46, XX Cell Line: Implications for Management

    PubMed Central

    Hipp, Lauren E.; Mohnach, Lauren; Wei, Sainan; Thomas, Inas H.; Elhassan, Maha; Sandberg, David E.; Quint, Elisabeth H.; Keegan, Catherine E.

    2016-01-01

    Carriers of isodicentric Y (idicY) mosaicism exhibit a wide range of clinical features, including short stature, gonadal abnormalities, and external genital anomalies. However, the phenotypic spectrum for individuals carrying an idicY and a 46, XX cell line is less clearly defined. A more complete description of the phenotype related to idicY is thus essential to guide management related to pubertal development, fertility, and gonadoblastoma risk in mosaic carriers. Findings from the evaluation of twin females with an abnormal karyotype, 48, XX, +idic(Yq)x2/47, XX, +idic(Yq)/46, XX, are presented to highlight the importance of interdisciplinary care in the management of multifaceted disorders of sex development. PMID:26407917

  14. Inverse participation ratios in the XX spin chain

    NASA Astrophysics Data System (ADS)

    Tsukerman, Emmanuel

    2017-03-01

    We continue the study of the inverse participation ratios (IPRs) of the XXZ Heisenberg spin chain initiated by Stéphan, Furukawa, Misguich, and Pasquier (2009) and continued by Misguich, Pasquier, and Luck (2016) by focusing on the case of the XX Heisenberg spin chain. For the ground state, Stéphan et al. note that calculating the IPR is equivalent to Dyson's constant term ex-conjecture. We express the IPRs of excited states as an apparently new "discrete" Hall inner product. We analyze this inner product using the theory of symmetric functions (Jack polynomials, Schur polynomials, the standard Hall inner product, and ωq ,t) to determine some exact expressions and asymptotics for IPRs. We show that IPRs can be indexed by partitions, and asymptotically the IPR of a partition is equal to that of the conjugate partition. We relate the IPRs to two other models from physics, namely, the circular symplectic ensemble of Dyson and the Dyson-Gaudin two-dimensional Coulomb lattice gas. Finally, we provide a description of the IPRs in terms of a signed count of diagonals of permutohedra.

  15. Thermodynamics of a dilute XX chain in a field

    NASA Astrophysics Data System (ADS)

    Timonin, P. N.

    2016-06-01

    Gapless phases in ground states of low-dimensional quantum spin systems are rather ubiquitous. Their peculiarity is a remarkable sensitivity to external perturbations due to permanent criticality of such phases manifested by a slow (power-low) decay of pair correlations and the divergence of the corresponding susceptibility. A strong influence of various defects on the properties of the system in such a phase can then be expected. Here, we consider the influence of vacancies on the thermodynamics of the simplest quantum model with a gapless phase, the isotropic spin-1/2 XX chain. The existence of the exact solution of this model gives a unique opportunity to describe in detail the dramatic effect of dilution on the gapless phase—the appearance of an infinite series of quantum phase transitions resulting from level crossing under the variation of a longitudinal magnetic field. We calculate the jumps in the field dependences of the ground-state longitudinal magnetization, susceptibility, entropy, and specific heat appearing at these transitions and show that they result in a highly nonlinear temperature dependence of these parameters at low T. Also, the effect of enhancement of the magnetization and longitudinal correlations in the dilute chain is established. The changes of the pair spin correlators under dilution are also analyzed. The universality of the mechanism of the quantum transition generation suggests that similar effects of dilution can also be expected in gapless phases of other low-dimensional quantum spin systems.

  16. Cytogenetic analysis of somatic and germinal cells from 38,XX/38,XY phenotypically normal boars.

    PubMed

    Barasc, Harmonie; Ferchaud, Stéphane; Mary, Nicolas; Cucchi, Marie Adélaïde; Lucena, Amalia Naranjo; Letron, Isabelle Raymond; Calgaro, Anne; Bonnet, Nathalie; Dudez, Anne Marie; Yerle, Martine; Ducos, Alain; Pinton, Alain

    2014-01-15

    Many chromosomal abnormalities have been reported to date in pigs. Most of them have been balanced structural rearrangements, especially reciprocal translocations. A few cases of XY/XX chimerism have also been diagnosed within the national systematic chromosomal control program of young purebred boars carried out in France. Until now, this kind of chromosomal abnormality has been mainly reported in intersex individuals. We investigated 38,XY/38,XX boars presenting apparently normal phenotypes to evaluate the potential effects of this particular chromosomal constitution on their reproductive performance. To do this, we analyzed (1) the chromosomal constitution of cells from different organs in one boar; (2) the aneuploidy rates for chromosomes X, Y, and 13 in sperm nuclei sampled from seven XY/XX boars. 2n = 38,XX cells were identified in different nonhematopoietic tissues including testis (frequency, <8%). Similar aneuploidy rates were observed in the sperm nuclei of XY/XX and normal individuals (controls). Altogether, these results suggest that the presence of XX cells had no or only a very limited effect on the reproduction abilities of the analyzed boars.

  17. Evaluation of MatriXX for IMRT and VMAT dose verifications in peripheral dose regions

    SciTech Connect

    Han Zhaohui; Ng, Sook Kien; Bhagwat, Mandar S.; Lyatskaya, Yulia; Zygmanski, Piotr

    2010-07-15

    Purpose: MatriXX is a two-dimensional ion chamber array designed for IMRT/VMAT (RapidArc, IMAT, etc.) dose verifications. Its dosimetric properties have been characterized for megavoltage beams in a number of studies; however, to the best of the authors' knowledge, there is still a lack of an investigation into its performance in the peripheral or low dose regions. In this work, the authors have carried out a systematic study on this issue. Methods: The authors compare the performance of MatriXX with a cylindrical ion chamber in solid water phantoms in the peripheral dose regions. The comparisons are performed for a number of typical irradiation conditions that involve different gantry and/or MLC motions, field sizes, and distances to the target including static gantry/open fields, static gantry/sweeping MLC gap (mimicking an IMRT delivery), dynamic gantry/oscillating sweeping MLC gap (mimicking a VMAT delivery), as well as clinical IMRT and VMAT plans. Results: MatriXX, when used according to the manufacturer's recommendations, is found to disagree with an ion chamber in peripheral dose regions. This disagreement has been attributed to four types of MatriXX errors, namely, positive bias, over-response to scattered doses, round-off error, and angular dependence, all of which contribute to dose inaccuracies in the peripheral regions. The positive bias, which is independent of the dose level, is cumulative when MatriXX operates in the movie mode. The accumulation is proportional to the number of movie frames (snaps) when the sampling time is greater than 500 ms and is proportional to the overall movie time for a sampling time shorter than 500 ms. This behavior suggests multiple sources of the bias. MatriXX is also found to over-respond to peripheral doses by about 2.0% for the regions investigated in this work (3-15 cm from the field edge), where phantom scatter and collimator scatter dominate. Round-off error is determined to be due to insufficient precision in

  18. Serbian Astronomers in Science Citation Index in the XX Century

    NASA Astrophysics Data System (ADS)

    Dimitrijevic, Milan S.

    "Alpha". In 1996 Zrenjanin too got an organization of amateur astronomers, Astronomical Society "Milutin Milankovic". Moreover, in the book is given a selected bibliography of references concerning the history of astronomy among Serbs in XX century.

  19. XY females do better than the XX in the African pygmy mouse, Mus minutoides.

    PubMed

    Saunders, Paul A; Perez, Julie; Rahmoun, Massilva; Ronce, Ophélie; Crochet, Pierre-André; Veyrunes, Frédéric

    2014-07-01

    All therian mammals have a similar XY/XX sex-determination system except for a dozen species. The African pygmy mouse, Mus minutoides, harbors an unconventional system in which all males are XY, and there are three types of females: the usual XX but also XX* and X*Y ones (the asterisk designates a sex-reversal mutation on the X chromosome). The long-term evolution of such a system is a paradox, because X*Y females are expected to face high reproductive costs (e.g., meiotic disruption and loss of unviable YY embryos), which should prevent invasion and maintenance of a sex-reversal mutation. Hence, mechanisms for compensating for the costs could have evolved in M. minutoides. Data gathered from our laboratory colony revealed that X*Y females do compensate and even show enhanced reproductive performance in comparison to the XX and XX*; they produce significantly more offspring due to (i) a higher probability of breeding, (ii) an earlier first litter, and (iii) a larger litter size, linked to (iv) a greater ovulation rate. These findings confirm that rare conditions are needed for an atypical sex-determination mechanism to evolve in mammals, and provide valuable insight into understanding modifications of systems with highly heteromorphic sex chromosomes.

  20. The Caenorhabditis Elegans Gene Sdc-2 Controls Sex Determination and Dosage Compensation in Xx Animals

    PubMed Central

    Nusbaum, C.; Meyer, B. J.

    1989-01-01

    We have identified a new X-linked gene, sdc-2, that controls the hermaphrodite (XX) modes of both sex determination and X chromosome dosage compensation in Caenorhabditis elegans. Mutations in sdc-2 cause phenotypes that appear to result from a shift of both the sex determination and dosage compensation processes in XX animals to the XO modes of expression. Twenty-eight independent sdc-2 mutations have no apparent effect in XO animals, but cause two distinct phenotypes in XX animals: masculinization, reflecting a defect in sex determination, and lethality or dumpiness, reflecting a disruption in dosage compensation. The dosage compensation defect can be demonstrated directly by showing that sdc-2 mutations cause elevated levels of several X-linked transcripts in XX but not XO animals. While the masculinization is blocked by mutations in sex determining genes required for male development (her-1 and fem-3), the lethality, dumpiness and overexpression of X-linked genes are not, indicating that the effect of sdc-2 mutations on sex determination and dosage compensation are ultimately implemented by two independent pathways. We propose a model in which sdc-2 is involved in the coordinate control of both sex determination and dosage compensation in XX animals and acts in the regulatory hierarchy at a step prior to the divergence of the two pathways. PMID:2759421

  1. A rare case of 46,XX gonadal dysgenesis and Mayer-Rokitansky-Kuster-Hauser syndrome

    PubMed Central

    Manne, Sriharibabu; Veeraabhinav, C. H.; Jetti, Mounica; Himabindu, Yalamanchali; Donthu, Kiranmai; Badireddy, Mutyalarayudu

    2016-01-01

    46,XX gonadal dysgenesis is a rare genetically heterogeneous disorder characterized by underdeveloped ovaries with consequent, impuberism, primary amenorrhea, and hypergonadotropic hypogonadism. Mullerian agenesis or Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is characterized by congenital aplasia of the uterus and the upper part (2/3) of the vagina in a woman with normal development of secondary sexual characteristics and a normal 46,XX karyotype. The phenotypic manifestations of MRKH syndrome may sometimes overlap with various other syndromes and require accurate delineation. The coexistence of both these disorders is extremely rare. Here, we report a case of 46,XX gonadal dysgenesis and MRKH syndrome with anatomically dispersed congenital anomalies unique among reported cases. PMID:28216916

  2. Long term outcomes in 46, XX adult patients with congenital adrenal hyperplasia reared as males.

    PubMed

    Khattab, A; Yau, M; Qamar, A; Gangishetti, P; Barhen, A; Al-Malki, S; Mistry, H; Anthony, W; Toralles, M B; New, Maria I

    2017-01-01

    Patients with Congenital Adrenal Hyperplasia (CAH) owing to 21-hydroxylase deficiency and whose karyotype is 46, XX are usually assigned to the female gender. Reported herein are the long term outcomes in three patients with CAH whose karyotype is 46, XX and who were reared as males. A retrospective review of three CAH patients with a 46, XX karyotype who were reared as males was conducted. Gender assignment, clinical and biochemical data, pre and post-genitoplasty genital examinations were reviewed. Gender identity was tested by an extensive questionnaire. Gender role, sexual preference, marital status and sexual satisfaction were evaluated by interview. The three patients were genotyped for the CYP21A2 gene confirming the diagnosis of CAH. Owing to genital virilization, cultural preferences for male gender and the lack of newborn screening programs the three patients reported herein were assigned to the male gender at birth before the diagnosis of CAH was established. In adulthood the patients remained significantly virilized. Thorough psychosexual assessments in adulthood revealed well established male gender identities compatible with their male gender assignments at birth. In all three patients, gender role and behavior were consistent with male gender identity including sexual intercourse with female partners. The three patients reported herein revealed that male gender assignment to CAH patients with a 46, XX karyotype may have a successful outcome providing there is strong parental support and expert endocrine care. No standard guidelines have been published for the gender assignment of CAH patients with a 46, XX karyotype and genital ambiguity. More studies concerning gender assignment in CAH patients with a 46, XX karyotype reared as males are needed.

  3. Excited state properties of naphtho-homologated xxDNA bases and effect of methanol solution, deoxyribose, and base pairing.

    PubMed

    Zhang, Laibin; Ren, Tingqi; Tian, Jianxiang; Yang, Xiuqin; Zhou, Liuzhu; Li, Xiaoming

    2013-04-18

    Design and synthesis of fluorescent nucleobase analogues for studying structures and dynamics of nucleic acids have attracted much attention in recent years. In the present work, a comprehensive theoretical study of electronic transitions of naphtho-homologated base analogues, namely, xxC, xxT, xxA, and xxG, was performed. The nature of the low-lying excited states was discussed, and the results were compared with those of x-bases. Geometrical characteristics of the lowest excited singlet ππ* states were explored using the CIS method. The calculated excitation maxima are 423, 397, 383, and 357 nm for xxA, xxG, xxC, and xxT, respectively, and they are greatly red-shifted compared with x-bases and natural bases, allowing them to be selectively excited in the presence of the natural bases. In the gas phase, the fluorescence from them would be expected to occur around 497, 461, 457, and 417 nm, respectively. The effects of methanol solution, deoxyribose, and base paring with their complementary natural bases on the relevant absorption and emission spectra of these modified bases were also examined.

  4. 78 FR 29131 - Solar Star California XX, LLC; Supplemental Notice that Initial Market-Based Rate Filing Includes...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-17

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Solar Star California XX, LLC; Supplemental Notice that Initial Market-Based... above-referenced proceeding, of Solar Star California XX, LLC's application for market-based...

  5. Das Schwimmen der Talitridae (Crustacea, Amphipoda): Funktionsmorphologie, Phänomenologie und Energetik

    NASA Astrophysics Data System (ADS)

    Vogel, Friedhelm

    1985-09-01

    The Talitridae, well-known for their jumping behaviour, swim with help of the tail-flip. This movement of the abdomen is also known from other amphipods like the Gammaridae which are normally not able to move by jerks outside the water. The suspected homology between the tail-flip when swimming and the jerky movement of the abdomen when jumping gave rise to this investigation, mainly based on high frequency film recordings, on the swimming of Hyale nilssonii, Orchestia cavimana, and Talitrus saltator (family Talitridae) as well as three related species of the families Gammaridae and Corophiidae. Comparative morphometrical and SEM-studies on the habitus of the species and the build of the involved limbs reveal the rather uniform construction of the Gammaridea; functional adaptation to the environment and to the way of living become apparent in minor alterations. The joints of the pleopods and uropods show a clear structural adaptation to the mechanical strain during swimming. The pleopods are moved metachronally in all examined species; angular velocity and rate of beating indicate the efficiency of the swimming movement. In the Talitridae, the metachronal beat of the pleopods is nearly always coupled with the tail-flip while in the Gammaridae and Corophiidae the tail-flip, in addition to the beat of the pleopods, is mostly used for a start from the subsoil or for a change in swimming direction. H. nilssonii, Gammarus locusta, and Corophium volutator, all inhabitants of the tidal zone in the North Sea shallows, turned out to be the “best” swimmers while the (semi-) terrestrially living species, O. cavimana and T. saltator, proved to be rather “poor” swimmers. This clearly indicates the ecological significance of swimming for the different species. Furthermore, the tailflip is found to be of rather subordinate importance. It contributes to a higher velocity if used moderately but is rather obstructive if a large angle is covered while extending and flexing the abdomen. The efficiency of swimming is inversely proportional to the efficiency of jumping in the three talitridean species. Thus, better adaptation to terrestrial life is accompanied by loss of swimming efficiency. Examined under the aspect of locomotional homology, it is concluded that the tail-flip used while swimming is homologous to the jerky movement of the abdomen used for jumping. The comparison of the swimming performance of the examined species with other crustaceans and some fishes illustrates the over-all good results of the Gammaridea.

  6. 49 CFR 1242.46 - Computers and data processing equipment (account XX-27-46).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Computers and data processing equipment (account XX-27-46). 1242.46 Section 1242.46 Transportation Other Regulations Relating to Transportation... RAILROADS 1 Operating Expenses-Equipment § 1242.46 Computers and data processing equipment (account...

  7. 49 CFR 1242.46 - Computers and data processing equipment (account XX-27-46).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Computers and data processing equipment (account XX-27-46). 1242.46 Section 1242.46 Transportation Other Regulations Relating to Transportation... RAILROADS 1 Operating Expenses-Equipment § 1242.46 Computers and data processing equipment (account...

  8. 49 CFR 1242.16 - Road property damaged-other (account XX-19-48).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Road property damaged-other (account XX-19-48). 1242.16 Section 1242.16 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) ACCOUNTS, RECORDS AND REPORTS SEPARATION OF COMMON OPERATING EXPENSES BETWEEN...

  9. 49 CFR 1242.46 - Computers and data processing equipment (account XX-27-46).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 9 2013-10-01 2013-10-01 false Computers and data processing equipment (account XX-27-46). 1242.46 Section 1242.46 Transportation Other Regulations Relating to Transportation... RAILROADS 1 Operating Expenses-Equipment § 1242.46 Computers and data processing equipment (account...

  10. 49 CFR 1242.46 - Computers and data processing equipment (account XX-27-46).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Computers and data processing equipment (account XX-27-46). 1242.46 Section 1242.46 Transportation Other Regulations Relating to Transportation... RAILROADS 1 Operating Expenses-Equipment § 1242.46 Computers and data processing equipment (account...

  11. 49 CFR 1242.46 - Computers and data processing equipment (account XX-27-46).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Computers and data processing equipment (account XX-27-46). 1242.46 Section 1242.46 Transportation Other Regulations Relating to Transportation... RAILROADS 1 Operating Expenses-Equipment § 1242.46 Computers and data processing equipment (account...

  12. 40 CFR Table 1 to Subpart Xx of... - Hazardous Air Pollutants

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 10 2011-07-01 2011-07-01 false Hazardous Air Pollutants 1 Table 1 to Subpart XX of Part 63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES...

  13. 40 CFR Table 1 to Subpart Xx of... - Hazardous Air Pollutants

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 10 2010-07-01 2010-07-01 false Hazardous Air Pollutants 1 Table 1 to Subpart XX of Part 63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES...

  14. 45,X/46,XX karyotype mitigates the aberrant craniofacial morphology in Turner syndrome.

    PubMed

    Rizell, Sara; Barrenäs, Marie-Louise; Andlin-Sobocki, Anna; Stecksén-Blicks, Christina; Kjellberg, Heidrun

    2013-08-01

    The aim of this project was to study the impact on craniofacial morphology from Turner syndrome (TS) karyotype, number of intact X chromosomal p-arms, and age as well as to compare craniofacial morphology in TS with healthy females. Lateral radiographs from 108 females with TS, ranging from 5.4 to 61.6 years, were analysed. The TS females were divided into four karyotype groups: 1. monosomy (45,X), 2. mosaic (45,X/46,XX), 3. isochromosome, and 4. other, as well as according to the number of intact X chromosomal p-arms. The karyotype was found to have an impact on craniofacial growth, where the mosaic group, with presence of 46,XX cell lines, seems to exhibit less mandibular retrognathism as well as fewer statistically significant differences compared to the reference group than the 45,X karyotype. Isochromosomes had more significant differences versus the reference group than 45,X/46,XX but fewer than 45,X. To our knowledge, this is the first time the 45,X/46,XX and isochromosome karyotypes are divided into separate groups studying craniofacial morphology. Impact from p-arm was found on both maxillary and mandibular length. Compared to healthy females, TS expressed a shorter posterior and flattened cranial base, retrognathic, short and posteriorly rotated maxilla and mandible, increased height of ramus, and relatively shorter posterior facial height. The impact of age was found mainly on mandibular morphology since mandibular retrognathism and length were more discrepant in older TS females than younger.

  15. [Diseases and causes of death of outstanding creative and scientific figures of XVII-XX centuries].

    PubMed

    Martsinkovs'kyĭ, I B

    2007-01-01

    The article reviewed the literature which analyzes clinical symptoms and causes of some creative and scientific figures of XVII-XX centuries. A conclusion has been made that there are not enough works with professional retrospective investigation of somatic diseases and causes of death of ukrainain outstanding cultural and scientific people in today's national medical literature.

  16. 46 XX karyotype during male fertility evaluation; case series and literature review

    PubMed Central

    Majzoub, Ahmad; Arafa, Mohamed; Starks, Christopher; Elbardisi, Haitham; Al Said, Sami; Sabanegh, Edmund

    2017-01-01

    Forty-six XX disorder of sex development is an uncommon medical condition observed at times during the evaluation of a man's fertility. The following is a case series and literature review of phenotypically normal men diagnosed with this karyotype. Our goal is to comprehend the patients’ clinical presentation as well as their laboratory results aiming to explore options available for their management. A formal literature review through PubMed and MEDLINE databases was performed using “46 XX man” as a word search. A total of 55 patients, including those conveyed in this article were diagnosed with a 46 XX karyotype during their fertility evaluation. The patients’ mean age ± s.d. was 34 ± 10 years and their mean height ± s.d. was 166 ± 6.5 cm. Overall, they presented with hypergonadotropic hypogonadism. Sexual dysfunction, reduced hair distribution, and gynecomastia were reported in 20% (4/20), 25.8% (8/31), and 42% (13/31) of the patients, respectively. The SRY gene was detected in 36 (83.7%) and was absent in the remaining seven (16.3%) patients. We found that a multidisciplinary approach to management is preferred in 46 XX patients. Screening for remnants of the mullerian ducts and for malignant transformation in dysgenetic gonads is imperative. Hypogonadism should be addressed, while fertility options are in vitro fertilization with donor sperm or adoption. PMID:27297128

  17. 76 FR 40282 - Proposed Generic Communications; Draft NRC Regulatory Issue Summary 2011-XX; NRC Regulation of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-08

    ... Summary 2011-XX; NRC Regulation of Military Operational Radium-226 AGENCY: Nuclear Regulatory Commission... sources of radium-226 under military control that are subject to NRC regulation pursuant to the Energy...: Draft NRC Regulatory Issue Summary 2011-XXXX; NRC Regulation of Military Operational...

  18. 76 FR 57006 - Proposed Generic Communications; Draft NRC Regulatory Issue Summary 2011-XX; NRC Regulation of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ...-XX; NRC Regulation of Military Operational Radium-226; Reopening of Comment Period AGENCY: Nuclear... military operational Radium-226 for a 60-day public comment period that ended on September 6, 2011. The NRC... amended its regulations to include jurisdiction over discrete sources of radium-226,...

  19. Studying the thermally entangled state of a three-qubit Heisenberg XX ring via quantum teleportation

    SciTech Connect

    Yeo, Ye

    2003-08-01

    We consider quantum teleportation as a tool to investigate the thermally entangled state of a three-qubit Heisenberg XX ring. Our investigation reveals interesting aspects of quantum entanglement not reflected by the pairwise thermal concurrence of the state. In particular, two mixtures of different pairs of W states, which result in the same concurrence, could yield very different average teleportation fidelities.

  20. 49 CFR 1242.11 - Administration-bridges and buildings (account XX-19-03).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... RAILROADS 1 Operating Expenses-Way and Structures § 1242.11 Administration—bridges and buildings (account XX-19-03). Separate common administration—bridges and buildings expenses between freight and passenger... 49 Transportation 9 2013-10-01 2013-10-01 false Administration-bridges and buildings (account...

  1. 49 CFR 1242.11 - Administration-bridges and buildings (account XX-19-03).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... RAILROADS 1 Operating Expenses-Way and Structures § 1242.11 Administration—bridges and buildings (account XX-19-03). Separate common administration—bridges and buildings expenses between freight and passenger... 49 Transportation 9 2012-10-01 2012-10-01 false Administration-bridges and buildings (account...

  2. 49 CFR 1242.11 - Administration-bridges and buildings (account XX-19-03).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... RAILROADS 1 Operating Expenses-Way and Structures § 1242.11 Administration—bridges and buildings (account XX-19-03). Separate common administration—bridges and buildings expenses between freight and passenger... 49 Transportation 9 2011-10-01 2011-10-01 false Administration-bridges and buildings (account...

  3. 49 CFR 1242.11 - Administration-bridges and buildings (account XX-19-03).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... RAILROADS 1 Operating Expenses-Way and Structures § 1242.11 Administration—bridges and buildings (account XX-19-03). Separate common administration—bridges and buildings expenses between freight and passenger... 49 Transportation 9 2010-10-01 2010-10-01 false Administration-bridges and buildings (account...

  4. 49 CFR 1242.11 - Administration-bridges and buildings (account XX-19-03).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... RAILROADS 1 Operating Expenses-Way and Structures § 1242.11 Administration—bridges and buildings (account XX-19-03). Separate common administration—bridges and buildings expenses between freight and passenger... 49 Transportation 9 2014-10-01 2014-10-01 false Administration-bridges and buildings (account...

  5. 49 CFR 1242.45 - Passenger and other revenue equipment (account XX-27-45).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Passenger and other revenue equipment (account XX-27-45). 1242.45 Section 1242.45 Transportation Other Regulations Relating to Transportation... RAILROADS 1 Operating Expenses-Equipment § 1242.45 Passenger and other revenue equipment (account...

  6. 49 CFR 1242.55 - Administration (account XX-51-01).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Administration (account XX-51-01). 1242.55 Section 1242.55 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) ACCOUNTS, RECORDS AND REPORTS SEPARATION OF...

  7. 49 CFR 1242.57 - Dispatching trains (account XX-51-58).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Dispatching trains (account XX-51-58). 1242.57 Section 1242.57 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) ACCOUNTS, RECORDS AND REPORTS SEPARATION OF...

  8. 49 CFR 1242.59 - Train inspection and lubrication (account XX-51-62).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Train inspection and lubrication (account XX-51-62). 1242.59 Section 1242.59 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) ACCOUNTS, RECORDS AND REPORTS SEPARATION OF...

  9. Diploid/Tetraploid Mosaicism in the Offspring of a 46XX/47XXX Mosaic Mother

    PubMed Central

    Reddy, Churku Mohan; Singh, D. N.; Crump, E. Perry

    1977-01-01

    A 10½-year-old boy with an IQ of 71, short stature, and isolated growth hormone deficiency was found to have diploid/tetraploid mosaicism. He was born to a 46xx/47xxx mosaic mother. The mother was found to be moderately mentally retarded but showed no other abnormalities. A review of literature pertinent to this case is presented. PMID:904007

  10. A mutation in the nucleoporin-107 gene causes XX gonadal dysgenesis

    PubMed Central

    Weinberg-Shukron, Ariella; Renbaum, Paul; Kalifa, Rachel; Zeligson, Sharon; Ben-Neriah, Ziva; Dreifuss, Amatzia; Abu-Rayyan, Amal; Maatuk, Noa; Fardian, Nilly; Rekler, Dina; Kanaan, Moien; Samson, Abraham O.; Levy-Lahad, Ephrat; Gerlitz, Offer; Zangen, David

    2015-01-01

    Ovarian development and maintenance are poorly understood; however, diseases that affect these processes can offer insights into the underlying mechanisms. XX female gonadal dysgenesis (XX-GD) is a rare, genetically heterogeneous disorder that is characterized by underdeveloped, dysfunctional ovaries, with subsequent lack of spontaneous pubertal development, primary amenorrhea, uterine hypoplasia, and hypergonadotropic hypogonadism. Here, we report an extended consanguineous family of Palestinian origin, in which 4 females exhibited XX-GD. Using homozygosity mapping and whole-exome sequencing, we identified a recessive missense mutation in nucleoporin-107 (NUP107, c.1339G>A, p.D447N). This mutation segregated with the XX-GD phenotype and was not present in available databases or in 150 healthy ethnically matched controls. NUP107 is a component of the nuclear pore complex, and the NUP107-associated protein SEH1 is required for oogenesis in Drosophila. In Drosophila, Nup107 knockdown in somatic gonadal cells resulted in female sterility, whereas males were fully fertile. Transgenic rescue of Drosophila females bearing the Nup107D364N mutation, which corresponds to the human NUP107 (p.D447N), resulted in almost complete sterility, with a marked reduction in progeny, morphologically aberrant eggshells, and disintegrating egg chambers, indicating defective oogenesis. These results indicate a pivotal role for NUP107 in ovarian development and suggest that nucleoporin defects may play a role in milder and more common conditions such as premature ovarian failure. PMID:26485283

  11. Prenatal diagnosis of 45,X/46,XX mosaicism and 45,X: implications for postnatal outcome.

    PubMed Central

    Koeberl, D D; McGillivray, B; Sybert, V P

    1995-01-01

    The prognosis for 45,X/46,XX mosaicism diagnosed prenatally has yet to be established. We report our experience with 12 patients in whom prenatal diagnosis of 45,X/46,XX mosaicism was detected by amniocentesis for advanced maternal age or decreased maternal serum alpha-feto protein and compared them with 41 45,X/46,XX patients diagnosed postnatally. The girls in the prenatal group range in age from 3 mo to 10 years. All have had normal linear growth. Four had structural anomalies including: ASD (n = 1); ptosis and esotropia (n = 1); labial fusion (n = 1); and urogenital sinus, dysplastic kidneys, and hydrometrocolpos (n = 1). Gonadotropins were measured in seven; one had elevated luteinizing hormone/FSH at 3 mo of age. One has developmental delay and seizures as well as ophthalmologic abnormalities. None would have warranted karyotyping for clinical suspicion of Turner syndrome. The prevalence of 45,X/46,XX mosaicism is 10-fold higher among amniocenteses than in series of postnatally diagnosed individuals with Turner syndrome, which suggests that most individuals with this karyotype escape detection and that an ascertainment bias exists toward those with clinically evident abnormalities. The phenomenon of a milder phenotype for the prenatal group is similar to that observed for 45,X/46,XY diagnosed prenatally. Prenatal counseling for 45,X/46,XX in the absence of such ultrasound abnormalities as hydrops fetalis should take into account the expectation of a milder phenotype (except, possibly, with respect to developmental delay) than that of patients ascertained postnatally. The same does not hold true for 45,x diagnosed prenatally. PMID:7668295

  12. Subtractive and differential hybridization molecular analyses of Ceratitis capitata XX/XY versus XX embryos to search for male-specific early transcribed genes.

    PubMed

    Salvemini, Marco; D'Amato, Rocco; Petrella, Valeria; Ippolito, Domenica; Ventre, Giuseppe; Zhang, Ying; Saccone, Giuseppe

    2014-01-01

    The agricultural pest Ceratitis capitata, also known as the Mediterranean fruit fly or Medfly, is a fruit crop pest of very high economic relevance in different continents. The strategy to separate Ceratitis males from females (sexing) in mass rearing facilities is a useful step before the sterilization and release of male-only flies in Sterile Insect Technique control programs (SIT). The identification of genes having early embryonic male-specific expression, including Y-linked genes, such as the Maleness factor, could help to design novel and improved methods of sexing in combination with transgenesis, aiming to confer conditional female-specific lethality or female-to-male sexual reversal. We used a combination of Suppression Subtractive Hybrydization (SSH), Mirror Orientation Selection (MOS) anddifferential screening hybridization (DSH) techniques to approach the problem of isolating corresponding mRNAs expressed in XX/XY embryos versus XX-only embryos during a narrow developmental window (8-10 hours after egg laying, AEL ). Here we describe a novel strategy we have conceived to obtain relatively large amounts of XX-only embryos staged at 8-10 h AEL and so to extract few micrograms of polyA+ required to apply the complex technical procedure. The combination of these 3 techniques led to the identification of a Y-linked putative gene, CcGm2, sharing high sequence identity to a paralogous gene, CcGm1, localized either on an autosome or on the X chromosome. We propose that CcGm2 is a first interesting putative Y-linked gene which could play a role in sex determination. The function exterted by this gene should be investigated by novel genetic tools, such as CRISPR-CAS9, which will permit to target only the Y-linked paralogue, avoiding to interfere with the autosomal or X-linked paralogue function.

  13. Subtractive and differential hybridization molecular analyses of Ceratitis capitata XX/XY versus XX embryos to search for male-specific early transcribed genes

    PubMed Central

    2014-01-01

    The agricultural pest Ceratitis capitata, also known as the Mediterranean fruit fly or Medfly, is a fruit crop pest of very high economic relevance in different continents. The strategy to separate Ceratitis males from females (sexing) in mass rearing facilities is a useful step before the sterilization and release of male-only flies in Sterile Insect Technique control programs (SIT). The identification of genes having early embryonic male-specific expression, including Y-linked genes, such as the Maleness factor, could help to design novel and improved methods of sexing in combination with transgenesis, aiming to confer conditional female-specific lethality or female-to-male sexual reversal. We used a combination of Suppression Subtractive Hybrydization (SSH), Mirror Orientation Selection (MOS) and differential screening hybridization (DSH) techniques to approach the problem of isolating corresponding mRNAs expressed in XX/XY embryos versus XX-only embryos during a narrow developmental window (8-10 hours after egg laying, AEL ). Here we describe a novel strategy we have conceived to obtain relatively large amounts of XX-only embryos staged at 8-10 h AEL and so to extract few micrograms of polyA+ required to apply the complex technical procedure. The combination of these 3 techniques led to the identification of a Y-linked putative gene, CcGm2, sharing high sequence identity to a paralogous gene, CcGm1, localized either on an autosome or on the X chromosome. We propose that CcGm2 is a first interesting putative Y-linked gene which could play a role in sex determination. The function exterted by this gene should be investigated by novel genetic tools, such as CRISPR-CAS9, which will permit to target only the Y-linked paralogue, avoiding to interfere with the autosomal or X-linked paralogue function. PMID:25472628

  14. Case of 46,XX/47,XY, +21 chimerism in a newborn infant with ambiguous genitalia

    SciTech Connect

    Sawai, Tomoko; Yoshimoto, Masaaki; Kinoshita, Ei-ichi; Baba, Tsuneyoshi; Matsumoto, Tadashi; Tsuji, Yoshiro, Niikawa, Norio; Fukuda, Shinpei; Harada, Naoki

    1994-02-15

    The authors describe the whole-body chimerism in a newborn infant with small phallus, pseudo-vaginal perineal hypospadias, and a bifid scrotum containing gonads. The human testis determining factor gene (SRY) was detected by PCR amplification. GTG-banding chromosome analysis in peripheral blood lymphocytes and cultured fibroblasts derived from right cubital skin showed a 46,XX/47,XY, +21 karyotype. Their ratios in each cell line were 294:5 and 178:7, respectively. QFQ-banding chromosome analysis documented 3 heteromorphic satellites on trisomic chromsomes 21 in the 47,XY,+21 cell line and a homozygous satellite pattern in the 46,XX cell line. Heteromorphic patterns of chromsomes 4, 13, 14, and 22 were also different between the two cell lines. To our knowledge, such disomy/trisomy chimeras have not been described previously. 10 refs., 3 figs.

  15. Genetic and physical analyses of Methylobacterium organophilum XX genes encoding methanol oxidation

    SciTech Connect

    Machlin, S.M.; Tam, P.E.; Bastien, C.A.; Hanson, R.S.

    1988-01-01

    When allyl alcohol was used as a suicide substrate, spontaneous mutants and UV light- and nitrous acid-generated mutants of Methylobacterium organophilum XX were selected which grew on methylamine but not on methanol. There was no detectable methanol dehydrogenase (MDH) activity in crude extracts of these mutants, yet Western blots revealed that some mutants still produced MDH protein. Complementation of 50 mutants by a cosmid gene bank of M. organophilum XX demonstrated that three major regions of the genome, each of which was separated by a minimum of 40 kilobases, were required for expression of active MDH. By subcloning and Tn5 insertion mutagenesis of subcloned fragments, at least 11 genes clustered within these three regions were subsequently identified. The identity of the MDH structural gene, which was initially determined by hybridization to the structural gene of Methylobacterium sp. strain AM1, was confirmed by Western blot analysis of an MDH-..beta..-galactosidase fusion protein.

  16. A real time integrated environment for Motorola 680xx-based VME and FASTBUS modules

    SciTech Connect

    Berg, D.; Heinicke, P.; MacKinnon, B.; Nicinski, T.; Oleynik, G.

    1989-05-01

    The Software Components Group pSOS operating system kernel and pROBE debugger have been extended to support the Fermilab PAN-DA system for a variety of Motorola 680xx-based VME and FASTBUS modules. These extensions include: a multi-tasking, reentrant implementation of Microtec C/Pascal; a serial port driver for terminal I/O and data transfer; a message reporting facility; and enhanced debugging tools. 5 refs., 1 fig.

  17. Military Process Specification for Type 46XX Powder-Forged Weapon Components

    DTIC Science & Technology

    1985-08-20

    one with low carbon or carburizing steels (Figure 18). Fracture Toughness Only one paper contained fracture toughness data for P/F 10XX steels . The...201-213. 8. Brown, G. T., "The Core ’Properties of a Range of Powder-Forged Steels ’ for Carburizing Applications," Powder Metallurgy, vol. 20, no...621205H84001, Dover, NJ: ARRADC0M, October 1980. Smith, A. 0., "Hardenability of Forged Alloy Steel Powders for Carburizing Ap- plications," Inland

  18. Teleportation via thermally entangled states of a two-qubit Heisenberg XX chain

    SciTech Connect

    Yeo Ye

    2002-12-01

    Recently, entanglement teleportation has been investigated by Lee and Kim [Phys. Rev. Lett. 84, 4236 (2000)]. In this paper we study entanglement teleportation via two separate thermally entangled states of a two-qubit Heisenberg XX chain. We established the condition under which the parameters of the model have to satisfy in order to teleport entanglement. The necessary minimum amount of thermal entanglement for some fixed strength of exchange coupling is a function of the magnetic field and the temperature.

  19. Discordant sex in monozygotic XXY/XX twins: a case report.

    PubMed

    Tachon, G; Lefort, G; Puechberty, J; Schneider, A; Jeandel, C; Boulot, P; Prodhomme, O; Meyer, P; Taviaux, S; Touitou, I; Pellestor, F; Geneviève, D; Gatinois, V

    2014-12-01

    We report a case of discordant phenotypic sex in monozygotic twins mosaic 47,XXY/46,XX: monozygotic heterokaryotypic twins. The twins presented with cognitive and comprehension delay, behavioural and language disorders, all symptoms frequently reported in Klinefelter syndrome. Molecular zygosity analysis with several markers confirmed that the twins are in effect monozygotic (MZ). Array comparative genomic hybridization found no evidence for the implication of copy number variation in the phenotypes. Ultrasound scans of the reproductive organs revealed no abnormalities. Endocrine tests showed a low testosterone level in Twin 1 (male phenotype) and a low gonadotrophin level in Twin 2 (female phenotype) which, combined with the results from ultrasound examination, provided useful information for potentially predicting the future fertility potential of the twins. Blood karyotypes revealed the presence of a normal 46,XX cell line and an aneuploïd 47,XXY cell line in both patients. Examination of the chromosome constitutions of various tissues such as blood, buccal smear and urinary sediment not surprisingly showed different proportions for the 46,XX and 47,XXY cell lines, which most likely explains the discordant phenotypic sex and mild Klinefelter features. The most plausible underlying biological mechanism is a post-zygotic loss of the Y chromosome in an initially 47,XXY zygote. This would result in an embryo with both 46,XX and 47,XXY cells lines which could subsequently divide into two monozygotic embryos through a twinning process. The two cell lines would then be distributed differently between tissues which could result in phenotypic discordances in the twins. These observations emphasize the importance of regular paediatric evaluations to determine the optimal timing for fertility preservation measures and to detect new Klinefelter features which could appear throughout childhood in the two subjects.

  20. [New aspects of diagnosing and treating pure gonadal dysgenesis 46XY and 46XX].

    PubMed

    Baron, J; Warenik-Szymankiewicz, A; Miedzianowski, J; Baron, J J

    1993-01-01

    Among 67 women with pure gonadal dysgenesis, karyotype 46XY was found in 46 and karyotype 46XX in 21 (26.3% of all intersexual subjects). Karyotype 46XY was either of pure type or mosaicism 45,X/46,XY (10.9%). Primary amenorrhea, underdevelopment of mammary glands and lack or poor development of pubic hair were the main complaints of the patients. In gonadal dysgenesis 46XY mammary glands were developed in 21.8% and pubic hair in 26% suggesting the presence within the gonads of the hormonally active tumor or the state after hormonal treatment. The patients with gonadal dysgenesis 46XX had lowered levels of estrogens and elevated levels of FSH and LH. Karyotype 46XY was not associated with evident changes in hormonal levels. Estrogens were both low and normal, and FSH was elevated (21.5 + 16.6 ug/ml) or normal (3.2-5.0 ng/ml). Total testosterone values were normal or slightly elevated. Such situation can be explained by the presence in some patients of tumors secreting either estrogens or androgens. Taeniform character of gonads was observed by ultrasonography whenever the presence of gonadal tumor was excluded. Histology of specimens taken from gonads or tumors demonstrated the presence of dysgerminoma or gonadoblastoma type of malignancy in 53.1%, foci or proliferation of the Leydig cells in 31.3% and typical morphology of residual gonads without germinal cells only in 12.5%. The differentiation between pure gonadal dysgenesis 46XX and primary ovarian insufficiency is required whenever no characteristic pattern emerges from clinical, hormonal, cytogenetic or ultrasonographic examination. Diagnosis of pure gonadal dysgenesis 46XX can be finally confirmed by the absence of gonocytes in the residual gonad. Besides of removal of gonads or tumors by surgery, the treatment of patients with 46XY karyotype consists in cyclic administration of estrogens and progestagens restoring menstruation and bringing development of secondary sex attributes.

  1. Long-distance entanglement and quantum teleportation in XX spin chains

    SciTech Connect

    Campos Venuti, L.; Giampaolo, S. M.; Illuminati, F.; Zanardi, P.

    2007-11-15

    Isotropic XX models of one-dimensional spin-1/2 chains are investigated with the aim to elucidate the formal structure and the physical properties that allow these systems to act as channels for long-distance, high-fidelity quantum teleportation. We introduce two types of models: (i) open, dimerized XX chains, and (ii) open XX chains with small end bonds. For both models we obtain the exact expressions for the end-to-end correlations and the scaling of the energy gap with the length of the chain. We determine the end-to-end concurrence and show that model (i) supports true long-distance entanglement at zero temperature, while model (ii) supports 'quasi-long-distance' entanglement that slowly falls off with the size of the chain. Due to the different scalings of the gaps, respectively exponential for model (i) and algebraic in model (ii), we demonstrate that the latter allows for efficient qubit teleportation with high fidelity in sufficiently long chains even at moderately low temperatures.

  2. Overrepresentation of the ACTN3 XX genotype in elite canoe and kayak paddlers.

    PubMed

    Orysiak, Joanna; Sitkowski, Dariusz; Zmijewski, Piotr; Malczewska-Lenczowska, Jadwiga; Cieszczyk, Pawel; Zembron-Lacny, Agnieszka; Pokrywka, Andrzej

    2015-04-01

    The aim of the study was to examine the association between the ACTN3 R577X polymorphism in canoe sprint athletes (canoe and kayak paddlers) and their results at 200- or 1000-m distance. Eighty-six European white male athletes divided into 2 groups-successful, who were outstanding at national championships, and nonsuccessful in these competitions-and 354 nonathletic controls were included in this study. The R577X polymorphism of ACTN3 was typed using PCR-RFLP. ACTN3 genotype distribution among all tested athletes and controls was in Hardy-Weinberg equilibrium. The odds ratio (OR) for successful 1000-m athletes harboring the XX genotype compared with sedentary controls was 2.95 (95% confidence interval [CI]: 1.37-6.35), but the OR for nonsuccessful 200-m athletes having the XX genotype compared with controls was 2.64 (95% CI: 1.30-5.36). These results suggest that factors associated with the ACTN3 XX genotype in canoe and kayak paddlers might provide some competitive advantage in performance at 1000 m, but it seems to limit at 200 m. Further studies aimed at development of training strategies based on genetic factors are needed.

  3. Impacts of shaking Bengkulus seismicity to subsurface Wellbore in the XX area

    NASA Astrophysics Data System (ADS)

    Rusli, Saifatur; Pratama, M. Ardian; Mardiyan, Hilman; Mirza, Finisha, Brian

    2016-05-01

    Bengkulu earthquake was happened on Wednesday, May 5th 2010 at 23:29:03 WIB (UTC-7) with magnitude 6.5 Richter scale. The Epicentrum was very close to Mentawai Fault System located on latitude 4.063°S and longitude 101.085°E with depth subsurface 27 kms. It was occurred the result of the Indian Ocean Plate-Australia's activity with low angled-subducted beneath the island of Sumatra. Shaking Bengkulus seismicity impacted subsurface in the XX Area which situated on South Palembang Sub-Basin part of South Sumatra Basin (SSB) about 200 kms far away from the epicentrum. Due to XX Area has some producing wells so that the seismicity activities as hypothetically impacts to Subsurface Wellbore which has caused some wells casing problems in the same depth. The wells casing problem shown after conducted routine sand bailer by Sand Line Unit, it was a downhole device used to remove debris sands or similar small particles around the fishingnecks of downhole tools or equipment in the wellbore, and then Sand Bailer tools got scratch at one side body. Similarly, Sand Bailer tools couldnt lowered until Total Depth and got samples sands slightly. At the end, it has impacted to well performance to produce oil in the XX Area.

  4. Wide spectrum of NR5A1-related phenotypes in 46,XY and 46,XX individuals.

    PubMed

    Domenice, Sorahia; Zamboni Machado, Aline; Moraes Ferreira, Frederico; Ferraz-de-Souza, Bruno; Marcondes Lerario, Antonio; Lin, Lin; Yumie Nishi, Mirian; Lisboa Gomes, Nathalia; Evelin da Silva, Thatiana; Barbosa Silva, Rosana; Vieira Correa, Rafaela; Ribeiro Montenegro, Luciana; Narciso, Amanda; Maria Frade Costa, Elaine; C Achermann, John; Bilharinho Mendonca, Berenice

    2016-12-01

    Steroidogenic factor 1 (NR5A1, SF-1, Ad4BP) is a transcriptional regulator of genes involved in adrenal and gonadal development and function. Mutations in NR5A1 have been among the most frequently identified genetic causes of gonadal development disorders and are associated with a wide phenotypic spectrum. In 46,XY individuals, NR5A1-related phenotypes may range from disorders of sex development (DSD) to oligo/azoospermia, and in 46,XX individuals, from 46,XX ovotesticular and testicular DSD to primary ovarian insufficiency (POI). The most common 46,XY phenotype is atypical or female external genitalia with clitoromegaly, palpable gonads, and absence of Müllerian derivatives. Notably, an undervirilized external genitalia is frequently seen at birth, while spontaneous virilization may occur later, at puberty. In 46,XX individuals, NR5A1 mutations are a rare genetic cause of POI, manifesting as primary or secondary amenorrhea, infertility, hypoestrogenism, and elevated gonadotropin levels. Mothers and sisters of 46,XY DSD patients carrying heterozygous NR5A1 mutations may develop POI, and therefore require appropriate counseling. Moreover, the recurrent heterozygous p.Arg92Trp NR5A1 mutation is associated with variable degrees of testis development in 46,XX patients. A clear genotype-phenotype correlation is not seen in patients bearing NR5A1 mutations, suggesting that genetic modifiers, such as pathogenic variants in other testis/ovarian-determining genes, may contribute to the phenotypic expression. Here, we review the published literature on NR5A1-related disease, and discuss our findings at a single tertiary center in Brazil, including ten novel NR5A1 mutations identified in 46,XY DSD patients. The ever-expanding phenotypic range associated with NR5A1 variants in XY and XX individuals confirms its pivotal role in reproductive biology, and should alert clinicians to the possibility of NR5A1 defects in a variety of phenotypes presenting with gonadal dysfunction

  5. SU-E-T-472: Improvement of IMRT QA Passing Rate by Correcting Angular Dependence of MatriXX

    SciTech Connect

    Chen, Q; Watkins, W; Kim, T; Neal, B

    2015-06-15

    Purpose: Multi-channel planar detector arrays utilized for IMRT-QA, such as the MatriXX, exhibit an incident-beam angular dependent response which can Result in false-positive gamma-based QA results, especially for helical tomotherapy plans which encompass the full range of beam angles. Although MatriXX can use with gantry angle sensor to provide automatically angular correction, this sensor does not work with tomotherapy. The purpose of the study is to reduce IMRT-QA false-positives by correcting for the MatriXX angular dependence. Methods: MatriXX angular dependence was characterized by comparing multiple fixed-angle irradiation measurements with corresponding TPS computed doses. For 81 Tomo-helical IMRT-QA measurements, two different correction schemes were tested: (1) A Monte-Carlo dose engine was used to compute MatriXX signal based on the angular-response curve. The computed signal was then compared with measurement. (2) Uncorrected computed signal was compared with measurements uniformly scaled to account for the average angular dependence. Three scaling factor (+2%, +2.5%, +3%) were tested. Results: The MatriXX response is 8% less than predicted for a PA beam even when the couch is fully accounted for. Without angular correction, only 67% of the cases pass the >90% points γ<1 (3%, 3mm). After full angular correction, 96% of the cases pass the criteria. Of three scaling factors, +2% gave the highest passing rate (89%), which is still less than the full angular correction method. With a stricter γ(2%,3mm) criteria, the full angular correction method was still able to achieve the 90% passing rate while the scaling method only gives 53% passing rate. Conclusion: Correction for the MatriXX angular dependence reduced the false-positives rate of our IMRT-QA process. It is necessary to correct for the angular dependence to achieve the IMRT passing criteria specified in TG129.

  6. Mosaic double aneuploidy (45,X/47,XX,+8) with aortic dissection.

    PubMed

    Lee, M N; Choi, K H; Kim, D K; Kim, S H

    2014-01-01

    Chromosomal aneuploidy is considerably frequent and may involve either autosomes or sex chromosomes. While double aneuploidy involving both autosomal and sex chromosomes is rare, several reports described the cases of sex chromosomal aneuploidies in combination with trisomy 21, such as Down-Klinefelter and Down-Turner syndrome. However, trisomy 8-Turner syndrome has been rarely described to date. Here we report a case of a 28-year-old female with mosaic trisomy 8-Turner syndrome. The patient was referred to our hospital for aortic dissection. On physical evaluation, features of her phenotype, which included short stature, webbed neck and cubitus valgus, suggested congenital anomalies such as Turner syndrome. Chest CT revealed aortic dissection with bicuspid aortic valve and coarctation. G-banding cytogenetic analysis of peripheral blood showed mosaicism with two cell lines (45,X[17]/47,XX,+8[33]). FISH analysis indicated that 15% of the cells were of monosomy X karyotype and 85% of the cells were with XX karyotype and trisomy 8 was detected only in XX cells. Though the patient exhibited clinical features of Turner syndrome, somatic stigmas present were not clearly distinguishable from those of trisomy 8, such as short stature, skeletal and cardiac abnormalities. Observations from most of the double aneuploidy cases indicated that the patient's phenotype was not necessarily in correlation to the ratio of autosomal and sex chromosomal aberrations. Mosaicism in trisomy 8-Turner syndrome was rarely documented and we believe this is the first reported case of mosaicism in trisomy 8-Turner syndrome presenting with aortic dissection and surviving into adulthood.

  7. Time-series Spectroscopy of the Pulsating Eclipsing Binary XX Cephei

    NASA Astrophysics Data System (ADS)

    Koo, Jae-Rim; Lee, Jae Woo; Hong, Kyeongsoo; Kim, Seung-Lee; Lee, Chung-Uk

    2016-03-01

    Oscillating Algol-type eclipsing binaries (oEA) are very interesting objects that have three observational features of eclipse, pulsation, and mass transfer. Direct measurement of their masses and radii from the double-lined radial velocity data and photometric light curves would be the most essential for understanding their evolutionary process and for performing the asteroseismological study. We present the physical properties of the oEA star XX Cep from high-resolution time-series spectroscopic data. The effective temperature of the primary star was determined to be 7946 ± 240 K by comparing the observed spectra and the Kurucz models. We detected the absorption lines of the secondary star, which had never been detected in previous studies, and obtained the radial velocities for both components. With the published BVRI light curves, we determined the absolute parameters for the binary via Wilson-Devinney modeling. The masses and radii are {M}1=2.49+/- 0.06 {M}⊙ , {M}2=0.38+/- 0.01 {M}⊙ , {R}1=2.27+/- 0.02 {R}⊙ , and {R}2=2.43+/- 0.02 {R}⊙ , respectively. The primary star is about 45% more massive and 60% larger than the zero-age main sequence stars with the same effective temperature. It is probably because XX Cep has experienced a very different evolutionary process due to mass transfer, contrasting with the normal main sequence stars. The primary star is located inside the theoretical instability strip of δ Sct-type stars on the HR diagram. We demonstrated that XX Cep is an oEA star, consisting of a δ Sct-type pulsating primary component and an evolved secondary companion.

  8. Analysis of low-density effects in suborbital flight of FAST20XX

    NASA Astrophysics Data System (ADS)

    Votta, Raffaele; Marini, Marco; Morsa, Luigi; Fels, Giorgio; Zuppardi, Gennaro; Schwanekamp, Tobias; Sippel, Martin

    2012-11-01

    The paper studies the high altitude effects to the future hypersonic/suborbital re-entry vehicle SpaceLiner developed in the framework of EC-funded FAST20XX project. Bridging functions have been developed and validated by means of DSMC calculations. The effects of rarefaction on global longitudinal aerodynamics of SpaceLiner in the range of altitude 65÷85 km have been pointed out by comparing to the aerodatabase in continuum regime conditions. DSMC computation has been done in the higher SpaceLiner altitude point confirming the bridging function results and providing heat transfer estimations.

  9. High reliability and high performance of 9xx-nm single emitter laser diodes

    NASA Astrophysics Data System (ADS)

    Bao, L.; Leisher, P.; Wang, J.; Devito, M.; Xu, D.; Grimshaw, M.; Dong, W.; Guan, X.; Zhang, S.; Bai, C.; Bai, J. G.; Wise, D.; Martinsen, R.

    2011-03-01

    Improved performance and reliability of 9xx nm single emitter laser diodes are presented. To date, over 15,000 hours of accelerated multi-cell lifetest reliability data has been collected, with drive currents from 14A to 18A and junction temperatures ranging from 60°C to 110°C. Out of 208 devices, 14 failures have been observed so far. Using established accelerated lifetest analysis techniques, the effects of temperature and power acceleration are assessed. The Mean Time to Failure (MTTF) is determined to be >30 years, for use condition 10W and junction temperature 353K (80°C), with 90% statistical confidence.

  10. 46,XX patients with congenital adrenal hyperplasia: initial assignment as male, reassigned female.

    PubMed

    Lee, Peter A; Witchel, Selma F

    2005-02-01

    Six 46,XX patients with congenital adrenal hyperplasia (CAH) presented with genital ambiguity, five so severe that initial gender assignment was male. Once diagnosis was realized, parents were involved in evaluation and chose sex re-assignment as female. To date, these girls and their parents all indicate satisfaction with their decision for a female sex of rearing. The girls have a female gender identity with behavior characteristics known for females with CAH. Thus, while outcome is satisfactory, it is realized that for most, expression of sexual orientation and adult life adjustments have not yet occurred.

  11. Presumptive mosaic origin of an XX/XY female with ambiguous genitalia.

    PubMed Central

    Zuffardi, O; Gargantini, L; Lambiase, S; Lo Curto, F; Maraschio, P; Ford, C E

    1987-01-01

    A child with ambiguous genitalia had an XX/XY karyotype in all tissues examined. Analyses of 11 informative polymorphisms, both chromosomal and genetic (Rh and HLA), showed no difference between the two cell lines. It is unlikely that the child originated from fertilisation of the egg and the second polar body by two sperms; therefore, we hypothesise that the child originated from an XXY zygote after mitotic errors during cleavage. Recent findings of differences in the chromosome constitution between the extra-embryonic tissues and the fetus support this view. PMID:3573003

  12. Skin pigment anomalies and mosaicism for a double autosomal trisomy (48,XX,+18,+20).

    PubMed

    Devriendt, K; Matthijs, G; Meireleire, J; Roelen, L; van Buggenhout, G; Fryns, J P

    1998-01-01

    We present a patient with profound mental retardation, epilepsy, facial dysmorphism and multiple skin hyper- and depigmentation areas. Karyotype in white blood cells was normal female, whereas in cultured skin fibroblasts originating from a depigmentated area, mosaic 48,XX,+18,+20 was found. Molecular analyses using polymorphic microsatellites showed a different origin of both additional chromosomes: maternal for the chromosome 20, paternal for chromosome 18. This, together with a mosaic state is consistent with a double postzygotic error in chromosome segregation possibly occurring in a single cell division.

  13. Klinefelter's syndrome in nontwin brothers and maternal XX/XXX mosaicism.

    PubMed

    Lodi, A; Monti, D; Gaspari, G; Ravaglia, G; Guadagni, C; Businello, M; Lamedica, R; Lenzi, S

    1979-01-01

    A case of two nontwin brothers, 19 and 17 years old, who had both Klinefelter's syndrome with a chromosomal mosaicism 46 XY/47 XXY, is reported here. The analysis of their mother's karyotype revealed a 46 XX/47 XXX mosaicism. It is hypothesized that the presence of an extra X chromosome in all three subjects could depend on the transmission of two X chromosomes from the mother to the sons or, less likely, on an increased liability to nondisjunction of the X chromosomes during one of the early mitotic divisions in the zygotes.

  14. Refining the regulatory region upstream of SOX9 associated with 46,XX testicular disorders of Sex Development (DSD).

    PubMed

    Hyon, Capucine; Chantot-Bastaraud, Sandra; Harbuz, Radu; Bhouri, Rakia; Perrot, Nicolas; Peycelon, Matthieu; Sibony, Mathilde; Rojo, Sandra; Piguel, Xavier; Bilan, Frederic; Gilbert-Dussardier, Brigitte; Kitzis, Alain; McElreavey, Ken; Siffroi, Jean-Pierre; Bashamboo, Anu

    2015-08-01

    Disorders of Sex Development (DSD) are a heterogeneous group of disorders affecting gonad and/or genito-urinary tract development and usually the endocrine-reproductive system. A genetic diagnosis is made in only around 20% of these cases. The genetic causes of 46,XX-SRY negative testicular DSD as well as ovotesticular DSD are poorly defined. Duplications involving a region located ∼600 kb upstream of SOX9, a key gene in testis development, were reported in several cases of 46,XX DSD. Recent studies have narrowed this region down to a 78 kb interval that is duplicated or deleted respectively in 46,XX or 46,XY DSD. We identified three phenotypically normal patients presenting with azoospermia and 46,XX testicular DSD. Two brothers carried a 83.8 kb duplication located ∼600 kb upstream of SOX9 that overlapped with the previously reported rearrangements. This duplication refines the minimal region associated with 46,XX-SRY negative DSD to a 40.7-41.9 kb element located ∼600 kb upstream of SOX9. Predicted enhancer elements and evolutionary-conserved binding sites for proteins known to be involved in testis determination are located within this region.

  15. Bilateral Ovotestes in a 78, XX SRY-Negative Beagle Dog.

    PubMed

    Pérez-Gutiérrez, José F; Monteagudo, Luís V; Rodríguez-Bertos, Antonio; García-Pérez, Enrique; Sánchez-Calabuig, María J; García-Botey, Concepción; Whyte, Ana; de la Muela, Mercedes Sánchez

    2015-01-01

    This report describes a disorder of the sexual development in a beagle dog resulting in an intersex condition. A 6 mo old beagle was presented for evaluation of a protruding structure from the vulva consistent with an enlarged clitoris. Ultrasonographic examination revealed the presence of both gonadal and uterine structures. Retrograde cystourethrovaginogram showed the presence of an os clitoris and severe vaginal stenosis. Histological studies revealed the presence of bilateral ovotestes and uterus. The gonad had interstitial cells within seminiferous-like tubules lined only with Sertoli cells and abundant interstitial cells among primordial, primary, and secondary follicles. Hormone assays completed before and after gonadohysterectomy showed an elevation in the levels of progesterone and dihydrotestosterone that returned to baseline 3 mo after surgery. Testosterone levels that were within the male reference ranges before surgery decreased to basal levels postsurgically. 17-β-Estradiol levels showed little variation and values were always within the reference ranges for a male. Cytogenetic analysis showed a normal female karyotype (2n = 78, XX) and polymerase chain reaction analysis revealed the absence of the sex-determining region Y gene. In summary, the dog presented bilateral ovotestes and a 2n = 78, XX chromosomal complement lacking the sex determining region Y gene, consistent with a diagnosis of true hermaphroditism.

  16. Evolution of Dosage Compensation in Anolis carolinensis, a Reptile with XX/XY Chromosomal Sex Determination

    PubMed Central

    Rupp, Shawn M.; Webster, Timothy H.; Olney, Kimberly C.; Hutchins, Elizabeth D.; Kusumi, Kenro

    2017-01-01

    In species with highly heteromorphic sex chromosomes, the degradation of one of the sex chromosomes will result in unequal gene expression between the sexes (e.g. between XX females and XY males) and between the sex chromosomes and the autosomes. Dosage compensation is a process whereby genes on the sex chromosomes achieve equal gene expression. We compared genome-wide levels of transcription between males and females, and between the X chromosome and the autosomes in the green anole, Anolis carolinensis. We present evidence for dosage compensation between the sexes, and between the sex chromosomes and the autosomes. When dividing the X chromosome into regions based on linkage groups, we discovered that genes in the first reported X-linked region, anole linkage group b (LGb), exhibit complete dosage compensation, although the rest of the X-linked genes exhibit incomplete dosage compensation. Our data further suggest that the mechanism of this dosage compensation is upregulation of the X chromosome in males. We report that approximately 10% of coding genes, most of which are on the autosomes, are differentially expressed between males and females. In addition, genes on the X chromosome exhibited higher ratios of nonsynonymous to synonymous substitution than autosomal genes, consistent with the fast-X effect. Our results from the green anole add an additional observation of dosage compensation in a species with XX/XY sex determination. PMID:28206607

  17. Congenital adrenal hyperplasia: surgical considerations required to repair a 46,XX patient raised as a boy.

    PubMed

    Dasgupta, Roshni; Schnitzer, J Jay; Hendren, W Hardy; Donahoe, Patricia K

    2003-08-01

    21-hydroxylase deficiency (P450 CYP21) accounts for 90% of cases of congenital adrenal hyperplasia (CAH), which is associated with abnormally low cortisol and high production of androgen precursors and is the most common cause of ambiguous genitalia. Increased androgen causes in utero virilization of the fetus, consisting of clitoral enlargement, an urogenital sinus, and labioscrotal enlargement and fusion. This is the first case in an experience covering more than 30 years, of a 46,XX patient raised as a boy. The authors report a case of a Pakistani patient born of a consanguineous union, who came to medical attention at age 3 because of severe genital ambiguity; genetic analyses showed that the child was a compound heterozygote for CAH. The surgical management of this patient consisted of (1) staged hypospadias repairs preceded by testosterone therapy, (2) creation of a bladder graft neourethra, (3) removal of müllerian structures, (4) correction of bifid prepenile scrotum, and (5) insertion of testicular prostheses. The commitment to raise a 46,XX child as a boy is a very rare event. With a series of staged complex surgical procedures and careful steroid replacement, normal secondary sexual characteristics can be achieved in these children.

  18. Non-Markovian dynamics in the extended cluster spin-1/2 XX chain

    NASA Astrophysics Data System (ADS)

    Mahmoudi, M.; Mahdavifar, S.; Zadeh, T. Mohammad Ali; Soltani, M. R.

    2017-01-01

    We study the dynamics of entanglement, mutual information, and quantum discord in the extended cluster spin-1/2 XX chain, equivalent to a one-dimensional spin-1/2 XX model with three-spin interaction (TSI). Selecting the nearest neighbor pair spins as an open quantum system, the rest of the chain plays the role of the environment. The two-point Heisenberg and the TSI are responsible for coupling between the system and the environment. Although the revival phenomenon of quantum correlations as an indication of non-Markovian dynamics is observed for TSI stronger than the Heisenberg interaction, the study of the trace distance has proven that the dynamical phase transition from the Markovian to the non-Markovian regime happens at a critical value where the TSI is equal to half of the Heisenberg interaction. By focusing on the nearest neighbor pair spins of the environment, we have also shown that the dynamics of quantum correlation in the environment is sensitive to Markovian and non-Markovian regions.

  19. High Temperature Increases the Masculinization Rate of the All-Female (XX) Rainbow Trout “Mal” Population

    PubMed Central

    Valdivia, Karina; Jouanno, Elodie; Volff, Jean-Nicolas; Galiana-Arnoux, Delphine; Guyomard, René; Helary, Louise; Mourot, Brigitte; Fostier, Alexis; Quillet, Edwige; Guiguen, Yann

    2014-01-01

    Salmonids are generally considered to have a robust genetic sex determination system with a simple male heterogamety (XX/XY). However, spontaneous masculinization of XX females has been found in a rainbow trout population of gynogenetic doubled haploid individuals. The analysis of this masculinization phenotype transmission supported the hypothesis of the involvement of a recessive mutation (termed mal). As temperature effect on sex differentiation has been reported in some salmonid species, in this study we investigated in detail the potential implication of temperature on masculinization in this XX mal-carrying population. Seven families issued from XX mal-carrying parents were exposed from the time of hatching to different rearing water temperatures ((8, 12 and 18°C), and the resulting sex-ratios were confirmed by histological analysis of both gonads. Our results demonstrate that masculinization rates are strongly increased (up to nearly two fold) at the highest temperature treatment (18°C). Interestingly, we also found clear differences between temperatures on the masculinization of the left versus the right gonads with the right gonad consistently more often masculinized than the left one at lower temperatures (8 and 12°C). However, the masculinization rate is also strongly dependent on the genetic background of the XX mal-carrying families. Thus, masculinization in XX mal-carrying rainbow trout is potentially triggered by an interaction between the temperature treatment and a complex genetic background potentially involving some part of the genetic sex differentiation regulatory cascade along with some minor sex-influencing loci. These results indicate that despite its rather strict genetic sex determinism system, rainbow trout sex differentiation can be modulated by temperature, as described in many other fish species. PMID:25501353

  20. SU-E-T-778: Use of the 2D MatriXX Detector for Measuring Scanned Ion Beam Parameters

    SciTech Connect

    Anvar, M Varasteh; Monaco, V; Sacchi, R; Guarachi, L Fanola; Cirio, R; Giordanengo, S; Marchetto, F; Vignati, A; Donetti, M; Ciocca, M; Panizza, D

    2015-06-15

    Purpose: The quality assurance (QA) procedure has to check the most relevant beam parameters to ensure the delivery of the correct dose to patients. Film dosimetry, which is commonly used for scanned ion beam QA, does not provide immediate results. The purpose of this work is to answer whether, for scanned ion beam therapy, film dosimetry can be replaced with the 2D MatriXX detector as a real-time tool. Methods: MatriXX, equipped with 32×32 parallel plate ion-chambers, is a commercial device intended for pre-treatment verification of conventional radiation therapy.The MatriXX, placed at the isocenter, and GAFCHROMIC films, positioned on the MatriXX entrance, were exposed to 131.44 MeV proton and 221.45 MeV/u Carbon-ion beams.The OmniPro-I’mRT software, applied for the data taking of MatriXX, gives the possibility of acquiring consecutive snapshots. Using the NI LabVIEW, the data from snapshots were logged as text files for further analysis. Radiochromic films were scanned with EPSON scanner and analyzed using software programs developed in-house for comparative purposes. Results: The field dose uniformity, flatness, beam position and beam width were investigated. The field flatness for the region covering 6×6 cm{sup 2} square field was found to be better than 2%. The relative standard deviations, expected to be constant over 2×2, 4×4 and 6×6 pixels from MatriXX measurement gives a uniformity of 1.5% in good agreement with the film results.The beam center position is determined with a resolution better than 200 µm for Carbon and less than 100 µm for proton beam.The FWHM determination for a beam wider than 10 mm is satisfactory, whilst for smaller beams the determination is uncertain. Conclusion: Precise beam position and fast 2D dose distribution can be determined in real-time using MatriXX detector. The results show that MatriXX is quick and accurate enough to be used in charged-particle therapy QA.

  1. 46, XX true hermaphroditism associated with a terminal deletion of the short arm of the X chromosome

    SciTech Connect

    Barbaux, S.; Vilain, E.; McElreavey, K.

    1994-09-01

    Testes are determined by the activity of the SRY gene product encoded by the Y chromosome. Mutations in SRY can lead to XY sex reversal (XY females) and the presence of the SRY gene in some XX individuals can lead either to complete (XX males) or incomplete (XX true hermaphrodites) sex reversal. Approximately 10% of XX true hermaphrodites contain a portion of the Y chromosome, including SRY, in their genome. The etiology of the remaining cases is unestablished but may be caused by mutations in other as yet unidentied sex determining genes downstream of SRY. Here we describe an SRY-negative true hermaphrodite with a 46,X,del(X)(p21.1-pter). The patient also presented with severe mental retardation, abnormal skin pigmentation and below average height. Histological examination of the gonad revealed bilateral ovotestis. We postulate that the Xp deletion has unmasked a recessive allele on the apparently normal X chromosome generating the intersex phenotype. This observation together with recent findings of certain XY females carrying duplications of Xp21.3 suggests that there may be a loci on Xp which acts as a switch in the testis/ovarian determination pathways.

  2. 49 CFR 1242.48 - Work and other non-revenue equipment (account XX-27-47).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Work and other non-revenue equipment (account XX-27-47). 1242.48 Section 1242.48 Transportation Other Regulations Relating to Transportation... RAILROADS 1 Operating Expenses-Equipment § 1242.48 Work and other non-revenue equipment (account...

  3. 75 FR 43165 - Information Collection; OMB Control No. 3090-00XX; FFATA Subaward and Executive Compensation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-23

    ... ADMINISTRATION Information Collection; OMB Control No. 3090-00XX; FFATA Subaward and Executive Compensation... and Executive Compensation Reporting Requirements. Public comments are particularly invited on: Whether this collection of information is necessary for the proper performance of functions of the...

  4. 49 CFR 1242.51 - Dismantling retired property and depreciation (accounts XX-27-39 and 62-27-00).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Dismantling retired property and depreciation (accounts XX-27-39 and 62-27-00). 1242.51 Section 1242.51 Transportation Other Regulations Relating to... FOR RAILROADS 1 Operating Expenses-Equipment § 1242.51 Dismantling retired property and...

  5. 49 CFR 1242.37 - Dismantling retired property and depreciation (accounts XX-26-39 and 62-26-00).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Dismantling retired property and depreciation (accounts XX-26-39 and 62-26-00). 1242.37 Section 1242.37 Transportation Other Regulations Relating to... FOR RAILROADS 1 Operating Expenses-Equipment § 1242.37 Dismantling retired property and...

  6. Acromegaly accompanied by Turner syndrome with 47,XXX/45,X/46,XX mosaicism.

    PubMed

    Yamazaki, Masanori; Sato, Ai; Nishio, Shin-ichi; Takeda, Teiji; Miyamoto, Takahide; Katai, Miyuki; Hashizume, Kiyoshi

    2009-01-01

    A 33-year-old woman was hospitalized for examination of edematous laryngopharynx. She was acromegalic. A pituitary adenoma with elevated serum levels of growth hormone (GH) and insulin-like growth factor-I (IGF-I) was detected, indicating acromegaly caused by GH-secreting pituitary adenoma. Multiple pigmented nevi were also noted without overt short stature and cubitus valgus. Chromosome analysis revealed that she had contracted Turner syndrome with 47,XXX/45,X/46,XX mosaicism. Transsphenoidal resection of the tumor decreased serum GH and IGF-I levels, but the edema was not improved. Both premature ovarian failure and hypertension appeared after surgery. This case may indicate the important relationships between GH/IGF-I and Turner syndrome.

  7. Geometric Quantum Discord in the Heisenberg XX Model with Three-Spin Interactions

    NASA Astrophysics Data System (ADS)

    Xie, Yu-Xia; Liu, Jing; Sun, Yu-Hang

    2017-02-01

    Quantum discord is a resource for quantum information processing tasks, and seeking flexible ways to control it is of practical significance. We investigate the trace distance, Bures distance, and Hellinger distance geometric quantum discords (GQDs) for thermal states of the Heisenberg XX chain with three-spin interactions. The results show that both the XZX + YZY and XZY - YZX types of three-spin interactions can be used to enhance evidently the GQDs for the boundary spins of the chain. The optimal strengths of three-spin interactions for which the maximum enhancement of the GQDs are achieved are strongly dependent on the GQD measures we adopted and the number of spins in the chain.

  8. Design of one large telescope direct drive control system based on TMS320F28xx

    NASA Astrophysics Data System (ADS)

    Song, Xiao-li; Wang, Da-xing; Zhang, Chao; Zhang, Zhen-chao; Chen, Li-yan; Ren, Chang-zhi

    2014-08-01

    The mount drive control is the key technique which mostly affects astronomical telescope's resolution and its speed. However, the ultra -lower speed and the giant moment of inertia make it very difficult to be controlled. In this paper, one segmented permanent-magnet synchronous motor (PMSM), 4m diameter, is suggested for the mount driving. A method is presented to drive the motor directly, which is based on TMS320F28XX and Insulated Gate Bipolar Transistor (IGBT) , also, HEIDENHAIN tape is used to detect the absolute position of the motor together with the Hall sensor. The segmented PMSM can work stable and the mount drive can realize nice tracking performance at ultra -lower speed with this drive system.

  9. Two XX males diagnosed in childhood. Endocrine, renal, and laboratory findings.

    PubMed Central

    Laurance, B M; Darby, C W; Vanderschueren-Lodeweyckx, M

    1976-01-01

    Two prepubertal boys with bilateral cryptorchidism were identified as 46,XX after nuclear sexing studies in several tissues. Gonadal histology and chromosome studies suggested that true hermaphroditism or mosaicism were unlikely. Xg blood grouping was informative in one patient. Accepting paternity, this suggested either that both Xs were maternal, with loss, for example, of the male determining Y chromosome, or that the paternal X chromosome did not express, probably because of a deletion, the allele for the positive Xg blood group. The patients had normal thyroid stimulating hormone reserves but subnormal responses to human chorionic gonadotrophin stimulation, and may need hormonal replacement at puberty. Both had renal anomalies. We suggest that chromosome analysis is essential when cryptorchidism, hypospadias, or microgenitalia are found and that an intravenous pyelogram is desirable. Images FIG. PMID:4036

  10. Aggregate model of cometary dust: an application to comet Levy 1990XX

    NASA Astrophysics Data System (ADS)

    Das, H. S.; Das, S. R.; Paul, T.; Suklabaidya, A.; Sen, A. K.

    2008-09-01

    In the present work, the light-scattering properties of comet Levy 1990XX are studied through simulations using Ballistic Particle-Cluster Aggregation (BPCA) or Ballistic Cluster-Cluster Aggregation (BCCA) aggregates of up to 128 spherical monomers of different compositions (e.g. silicates, carbonaceous materials etc.) and the best-fitting theoretical polarization curve is generated using the SUPERPOSITION T-MATRIX code. The best-fitting refractive indices coming out from the present analysis show silicate behaviour when monomer radius is am = 0.12μm and provide excellent results on the maximum and negative degrees of linear polarization at a single wavelength λ = 0.485μm for BCCA aggregates.

  11. Gender of rearing and psychosocial aspect in 46 XX congenital adrenal hyperplasia

    PubMed Central

    Gangaher, Arushi; Jyotsna, Viveka P.; Chauhan, Vasundhera; John, Jomimol; Mehta, Manju

    2016-01-01

    Background: In congenital adrenal hyperplasia (CAH) with ambiguous genitalia, assigning gender of rearing can be complex, especially If genitalia is highly virilized. Apart from karyotype, prenatal androgen exposure, patient's gender orientation, sociocultural, and parental influences play a role. The aim of this study was to assess gender dysphoria and psychosocial issues in patients of CAH raised as males and females. Materials and Methods: This is a cross-sectional study that includes patients (old and new) with CAH who were treated by us in the last 6 months. A semi-structured interview proforma was used to elicit history and psychosocial background of the patients. The clinical and biochemical details were noted. For psychological analysis, patients were screened for gender dysphoria using Parent Report Gender Identity Questionnaire for children <12 years and Gender Identity/Gender Dysphoria Questionnaire for Adolescents and Adults. Results: We analyzed 22 46 XX CAH patients among which, 3 were reared as males and 19 as females. Among the 19 patients reared as females, 17 patients showed no gender dysphoria. Two patients revealed gender dysphoria as indicated by their marginally low scores on the gender dysphoria assessment. However, in view of current literature and the age groups of the patients, behavior of the 6-year-old patient can be best understood as being tomboyish. Gender dysphoria in the 22-year-old can be explained by the dominance of psychosocial factors and not hormones alone. Among the three patients reared as males, two prepubertal were satisfied with their male gender identity. The third patient, aged 32 years, had gender dysphoria when reared as a male that resolved when gender was reassigned as female and feminizing surgery was done. Conclusion: Gender assignment in 46 XX CAH is guided by factors such as degree of virilization of genitalia, gender orientation, patient involvement, sociocultural, and parental influences. PMID:27867895

  12. Research on 9xx nm diode laser for direct and pumping applications

    NASA Astrophysics Data System (ADS)

    Sebastian, J.; Hülsewede, R.; Pietrzak, A.; Zorn, M.; Wölz, M.; Meusel, J.; Schröder, M.; Wittschirk, Th.

    2015-02-01

    High-power laser bars and single emitters have proven as attractive light sources for many industrial applications such as direct material processing or as pump sources for solid state and fiber-lasers. There is also a great interest in quasi-CW laser bars for high-energy projects. These applications require a continuous improvement of laser diodes for reliable optical output powers, high electrical-to-optical efficiencies, brightness and costs. In this paper JENOPTIK presents an overview of recent research for highly efficient CW and quasi-CW laser devices emitting in a wide wavelength range between 880 nm and 1020 nm. The last research results concern the 9xx single emitters and laser arrays. The 9xx nm 12 W single emitters and 976 nm 55 W laser arrays have efficiencies above 65%. New life time tests for single emitter devices currently exceed 1300 hours of reliable operation at room temperature and over 1500 hours at 45°C. Because of the small far field distribution of the optical power, the high output power and the small near field the 55 W arrays show a brightness of 75 MW x cm-2sr-1 with 95% power content. The technology for new generation 940 nm high fill-factor bars has been currently extended to emission wavelengths of 976 nm and 1020 nm with excellent results: 200 W output power with 63% efficiency using passive cooling. The innovative design of the laser structure enables, moreover, the realization of 500 W 880 nm quasi-CW laser bars with wall-plug efficiencies of 55% and a narrow fast-axis divergence angle of 40° (95% power content).

  13. Uniparental Disomy in Somatic Mosaicism 45,X/46,XY/46,XX Associated with Ambiguous Genitalia.

    PubMed

    Serra, Alexandre; Denzer, Friederike; Hiort, Olaf; Barth, Thomas F; Henne-Bruns, Doris; Barbi, Gotthold; Rettenberger, Günther; Wabitsch, Martin; Just, Walter; Leriche, Clothilde

    2015-01-01

    Disorders of sex development (DSD) affect the development of chromosomal, gonadal and/or anatomical sex. We analyzed a patient with ambiguous genitalia aiming to correlate the genetic findings with the phenotype. Blood and tissue samples from a male patient with penoscrotal hypospadias were analyzed by immunohistochemistry, karyotyping and FISH. DNA was sequenced for the AR, SRY and DHH genes, and further 26 loci in different sex chromosomes were analyzed by MLPA. The gonosomal origin was evaluated by simple tandem repeat (STR) analysis and SNP array. Histopathology revealed a streak gonad, a fallopian tube and a rudimentary uterus, positive for placental alkaline phosphatase, cytokeratin-7 and c-kit, and negative for estrogen, androgen and progesterone receptors, alpha-inhibin, alpha-1-fetoprotein, β-hCG, and oct-4. Karyotyping showed a 45,X/46,XY mosaicism, yet FISH showed both 46,XX/46,XY mosaicism (gonad and urethral plate), 46,XX (uterus and tube) and 46,XY karyotypes (rudimentary testicular tissue). DNA sequencing revealed intact sequences in SOX9, WNT4, NR0B1, NR5A1, CYP21A2, SRY, AR, and DHH. STR analysis showed only one maternal allele for all X chromosome markers (uniparental isodisomy, UPD), with a weaker SRY signal and a 4:1 ratio in the X:Y signal. Our findings suggest that the observed complex DSD phenotype is the result of somatic gonosomal mosaicism and UPD despite a normal blood karyotype. The presence of UPD warrants adequate genetic counseling for the family and frequent, lifelong, preventive follow-up controls in the patient.

  14. Rare case of massive congenital bilateral chylothorax in a hydropic fetus with true mosaicism 47,XXX/46,XX.

    PubMed

    Cremonini, Giorgio; Poggi, Alice; Capucci, Roberta; Vesce, Fortunato; Patella, Alfredo; Marci, Roberto

    2014-01-01

    Fetal congenital chylothorax is a rare condition that occurs sporadically or can be associated with abnormal karyotype or structural chromosomal anomalies. We report a unique case of fetal congenital bilateral chylothorax associated with mosaicism 47,XXX/46,XX. A female fetus affected by massive bilateral hydrothorax and ascites was diagnosed at 34(+1) weeks of gestation. Previous ultrasonographic exams were completely normal. Immune causes of hydrops were excluded. Elective cesarean section was performed soon after bilateral thoracocentesis. The analysis of drained pleural fluid revealed its lymphatic nature. The fetal karyotyping, performed on chorionic villi at the 11th week, had shown mosaicism 47,XXX/46,XX, later confirmed in the newborn's blood. We hypothesized that chylothorax may be part of the phenotypic spectrum of 47 XXX karyotype and we suggest an ultrasound follow-up of the fetus at closer intervals than the routine timing for this condition, even if it is not usually characterized by severe phenotypic features.

  15. A 45,XX,-5,-14,+t(5q;14q)mat cri du chat child.

    PubMed

    Bass, H N; Sparkes, R S; Crandall, B F; Galos, K J; Howard, J

    1978-03-01

    A two-year-old girl has the following features of the cri du chat syndrome: microcephaly, hypertelorism, downward slanting of the palpebral fissures, psychomotor retardation and a cat-like cry. She is only of five patients having the cat cry syndrome with 45 chromosomes. Her karyotype is 45,XX, -5, -14, +t(5; 14)(5qter leads to 5p11: : 14q11 leads to 14qter) with the translocation inherited from her mother and maternal grandmother, each of whom is the carrier of a balanced translocation 46,XX,t(5;14)(p11q11). Normal plasma activity for hexosaminidase B suggests the locus for this enzyme is not located in the delected segment of 5 p.

  16. XX true hemaphroditism in Southern Africa blacks: Exclusion of SRY sequences and uniparental disomy of the X chromosome

    SciTech Connect

    Spurdle, A.B.; Shankman, S.; Ramsay, M.

    1995-01-02

    A molecular investigation of 16 Bantu-speaking Black XX true hermaphrodites was undertaken in an attempt to determine the cause of the disorder. Y-specific sequences, including sequences mapping to the sex-determining region of the Y, were shown to be absent from lymphocyte tissue of all 16 patients tested. Y chromosome sequences were also absent from the ovarian and testicular components of both ovotestes of a single XX true hermaphrodite, thus excluding gonadal mosaicism involving Y chromosome sequences. Since there is evidence of Xp genes involved in testis determination/differentiation, uniparental disomy of the X chromosome was investigated in 14 XXTH families. Uniparental disomy was excluded in 12 of the 14 families, and isodisomy was excluded in the remaining two cases. 29 refs., 2 tabs.

  17. Combined Leydig cell and Sertoli cell dysfunction in 46,XX males lacking the sex determining region Y gene

    SciTech Connect

    Turner, B.; Vordermark, J.S.; Fechner, P.Y.

    1995-07-03

    We have evaluated 3 individuals with a rare form of 46,XX sex reversal. All of them had ambiguous external genitalia and mixed wolffian and muellerian structures, indicating both Leydig cell and Sertoli cell dysfunction, similar to that of patients with true hermaphroditism. However, gonadal tissue was not ovotesticular but testicular with varying degrees of dysgenesis. SRY sequences were absent in genomic DNA from peripheral leukocytes in all 3 subjects. Y centromere sequences were also absent, indicating that testis development did not occur because of a low level mosaicism of Y-bearing cells. The subjects in this report demonstrate that there is a continuum in the extent of the testis determination in SRY-negative 46,XX sex reversal, ranging from nearly normal to minimal testicular development. 20 refs.

  18. Terminal deletion of the long arm of chromosome 3 [46,XX,del(3)(q27{r_arrow}qter)

    SciTech Connect

    Chitayat, D.; Babul, R.; Silver, M.M.

    1996-01-02

    We report on a terminal deletion of the long arm of chromosome 3[46,XX,del(3)(q27{r_arrow}qter)] in a female newborn infant who died 45 hours after delivery and had multiple congenital abnormalities including bilateral anophthalmia, congenital heart disease, and abnormal genitalia. The findings are compared to those of four previously reported cases with terminal de (3q). 8 refs., 4 figs., 1 tab.

  19. Molecular cytogenetic characterization of Rumex papillaris, a dioecious plant with an XX/XY(1)Y (2) sex chromosome system.

    PubMed

    Navajas-Pérez, Rafael; Schwarzacher, Trude; Rejón, Manuel Ruiz; Garrido-Ramos, Manuel A

    2009-01-01

    Rumex papillaris Boiss, & Reut., an Iberian endemic, belongs to the section Acetosa of the genus Rumex whose main representative is R. acetosa L., a species intensively studied in relation to sex-chromosome evolution. Here, we characterize cytogenetically the chromosomal complement of R. papillaris in an effort to enhance future comparative genomic approaches and to better our understanding of sex chromosome structure in plants. Rumex papillaris, as is common in this group, is a dioecious species characterized by the presence of a multiple sex chromosome system (with females 2n = 12 + XX and males 2n = 12 + XY(1)Y(2)). Except for the X chromosome both Y chromosomes are the longest in the karyotype and appear heterochromatic due to the accumulation of at least two satellite DNA families, RAE180 and RAYSI. Each chromosome of pair VI has an additional major heterochromatin block at the distal region of the short arm. These supernumerary heterochromatic blocks are occupied by RAE730 satellite DNA family. The Y-related RAE180 family is also present in an additional minor autosomal locus. Our comparative study of the chromosomal organization of the different satellite-DNA sequences in XX/XY and XX/XY(1)Y(2) Rumex species demonstrates that of active mechanisms of heterochromatin amplification occurred and were accompanied by chromosomal rearrangements giving rise to the multiple XX/XY(1)Y(2) chromosome systems observed in Rumex. Additionally, Y(1) and Y(2) chromosomes have undergone further rearrangements leading to differential patterns of Y-heterochromatin distribution between Rumex species with multiple sex chromosome systems.

  20. [THE IMPROVEMENT OF CITIES AND SANITARY CONTROL IN RUSSIA IN LATE XIX--EARLY XX CENTURIES].

    PubMed

    Sherstneva, E V

    2015-01-01

    The article considers activity of municipal self-governments of Russia concerning support of sanitary epidemiological well-being of cities in the late XIX--early XX centuries. The acuteness of problem of sanitary conditions of urban settlements particularly became visible in post-reform period due to increasing of number of urban population, alteration of setup and rhythm of life in cities, appearance of new forms of worker's daily chores. Al this, against the background of underdevelopment of communal sphere aggravated epidemiological situation in cities. The impulse to improvement and development of sanitary control was made by the city regulations of 1870 presenting to town authorities the right to deal with sanitary issues. The significant input into improvement of cities was made first of all at the expense of construction of water supplies and sewerage and support of sanitary control of these spheres of municipal economy. Under town councils of many cities the sanitary commissions were organized to support permanent sanitary control in town. The development of town sanitation followed the way of specialization. The housing and communal, trade and food, school and sanitary and sanitary and veterinary control were organized.

  1. XX/XY System of Sex Determination in the Geophilomorph Centipede Strigamia maritima

    PubMed Central

    Green, Jack E.; Dalíková, Martina; Sahara, Ken; Marec, František; Akam, Michael

    2016-01-01

    We show that the geophilomorph centipede Strigamia maritima possesses an XX/XY system of sex chromosomes, with males being the heterogametic sex. This is, to our knowledge, the first report of sex chromosomes in any geophilomorph centipede. Using the recently assembled Strigamia genome sequence, we identified a set of scaffolds differentially represented in male and female DNA sequence. Using quantitative real-time PCR, we confirmed that three candidate X chromosome-derived scaffolds are present at approximately twice the copy number in females as in males. Furthermore, we confirmed that six candidate Y chromosome-derived scaffolds contain male-specific sequences. Finally, using this molecular information, we designed an X chromosome-specific DNA probe and performed fluorescent in situ hybridization against mitotic and meiotic chromosome spreads to identify the Strigamia XY sex-chromosome pair cytologically. We found that the X and Y chromosomes are recognizably different in size during the early pachytene stage of meiosis, and exhibit incomplete and delayed pairing. PMID:26919730

  2. XX/XY System of Sex Determination in the Geophilomorph Centipede Strigamia maritima.

    PubMed

    Green, Jack E; Dalíková, Martina; Sahara, Ken; Marec, František; Akam, Michael

    2016-01-01

    We show that the geophilomorph centipede Strigamia maritima possesses an XX/XY system of sex chromosomes, with males being the heterogametic sex. This is, to our knowledge, the first report of sex chromosomes in any geophilomorph centipede. Using the recently assembled Strigamia genome sequence, we identified a set of scaffolds differentially represented in male and female DNA sequence. Using quantitative real-time PCR, we confirmed that three candidate X chromosome-derived scaffolds are present at approximately twice the copy number in females as in males. Furthermore, we confirmed that six candidate Y chromosome-derived scaffolds contain male-specific sequences. Finally, using this molecular information, we designed an X chromosome-specific DNA probe and performed fluorescent in situ hybridization against mitotic and meiotic chromosome spreads to identify the Strigamia XY sex-chromosome pair cytologically. We found that the X and Y chromosomes are recognizably different in size during the early pachytene stage of meiosis, and exhibit incomplete and delayed pairing.

  3. The Sertoli Cell Only Syndrome and Glaucoma in a Sex – Determining Region Y (SRY) Positive XX Infertile Male

    PubMed Central

    Jain, Manish; V, Veeramohan; Chaudhary, Isha; Halder, Ashutosh

    2013-01-01

    The XX male syndrome is a rare genetic disorder. The phenotype is variable; it ranges from a severe impairment of the external genitalia to a normal male phenotype with infertility. It generally results from an unequal crossing over between the short arms of the sex chromosomes (X and Y). We are reporting a case of a 38-year-old man who presented with infertility and the features of hypogonadism and glaucoma. The examinations revealed normal external male genitalia, soft small testes, gynaecomastia and glaucoma. The semen analysis showed azoospermia. The serum gonadotropins were high, with low Anti Mullerian Hormone (AMH) and Inhibin B levels. The chromosomal analysis demonstrated a 46, XX karyotype. Fluorescent In-Situ Hybridization (FISH) and Polymerase Chain Reaction (PCR) revealed the presence of a Sex-determining Region Y (SRY). Testicular Fine Needle Aspiration Cytology (FNAC) revealed the Sertoli Cell Only Syndrome (SCOS). The presence of only Sertoli Cells in the testes, with glaucoma in the XX male syndrome, to our knowledge, has not been reported in the literature. PMID:23998093

  4. Unique sex chromosome systems in Ellobius: How do male XX chromosomes recombine and undergo pachytene chromatin inactivation?

    PubMed

    Matveevsky, Sergey; Bakloushinskaya, Irina; Kolomiets, Oxana

    2016-07-18

    Most mammalian species have heteromorphic sex chromosomes in males, except for a few enigmatic groups such as the mole voles Ellobius, which do not have the Y chromosome and Sry gene. The Ellobius (XX ♀♂) system of sex chromosomes has no analogues among other animals. The structure and meiotic behaviour of the two X chromosomes were investigated for males of the sibling species Ellobius talpinus and Ellobius tancrei. Their sex chromosomes, despite their identical G-structure, demonstrate short synaptic fragments and crossover-associated MLH1 foci in both telomeric regions only. The chromatin undergoes modifications in the meiotic sex chromosomes. SUMO-1 marks a small nucleolus-like body of the meiotic XX. ATR and ubiH2A are localized in the asynaptic area and the histone γH2AFX covers the entire XX bivalent. The distribution of some markers of chromatin inactivation differentiates sex chromosomes of mole voles from those of other mammals. Sex chromosomes of both studied species have identical recombination and meiotic inactivation patterns. In Ellobius, similar chromosome morphology masks the functional heteromorphism of the male sex chromosomes, which can be seen at meiosis.

  5. Unique sex chromosome systems in Ellobius: How do male XX chromosomes recombine and undergo pachytene chromatin inactivation?

    PubMed Central

    Matveevsky, Sergey; Bakloushinskaya, Irina; Kolomiets, Oxana

    2016-01-01

    Most mammalian species have heteromorphic sex chromosomes in males, except for a few enigmatic groups such as the mole voles Ellobius, which do not have the Y chromosome and Sry gene. The Ellobius (XX ♀♂) system of sex chromosomes has no analogues among other animals. The structure and meiotic behaviour of the two X chromosomes were investigated for males of the sibling species Ellobius talpinus and Ellobius tancrei. Their sex chromosomes, despite their identical G-structure, demonstrate short synaptic fragments and crossover-associated MLH1 foci in both telomeric regions only. The chromatin undergoes modifications in the meiotic sex chromosomes. SUMO-1 marks a small nucleolus-like body of the meiotic XX. ATR and ubiH2A are localized in the asynaptic area and the histone γH2AFX covers the entire XX bivalent. The distribution of some markers of chromatin inactivation differentiates sex chromosomes of mole voles from those of other mammals. Sex chromosomes of both studied species have identical recombination and meiotic inactivation patterns. In Ellobius, similar chromosome morphology masks the functional heteromorphism of the male sex chromosomes, which can be seen at meiosis. PMID:27425629

  6. Sex steroid levels in XY males and sex-reversed XX males, of rainbow trout (Oncorhynchus mykiss), during the reproductive cycle.

    PubMed

    Espinosa, E; Josa, A; Gil, L; González, N

    2011-02-01

    In this study, the annual cycle of the gonadal steroids testosterone (T), 11-ketotestosterone (11-KT), 17β-oestradiol (E2) and 17α, 20β-dihydroxy-4-pregnen-3-one (DHP) was determined using radioimmunoassay and then compared, for XY males (n=35) and sex-reversed XX males (n=27) rainbow trout, to establish possible endocrinology differences. Both in XY males and sex-reversed XX males, significant correlation was shown between body weight and T (r=0.5046 and 0.34078, respectively; p<0.0001) or KT (r=0.52494 and 0.43545, respectively; p<0.0001) concentrations. Plasma androgen levels in XY and sex-reversed XX males were similar and showed an intense seasonal variation. The highest levels for T and 11-KT were detected from December to April with a peak in January (51.67 ± 5.11 and 61.95 ± 4.25 ng/ml, for XY males and 57.1 ± 5.82 and 59.27 ± 4.84 ng/ml, respectively, for XX males). In addition, there was a positive correlation (p<0.0001) between T and 11-KT levels for XY males (r=0.7533) and sex-reversed XX males (r=0.6019). Concentrations of DHP in XY males also showed seasonal variation with a peak in February (25.18 ± 12.99 ng/ml). However, DHP levels in sex-reversed XX males were undetectable (<0.1 ng/ml) over the year. Levels of E2 were undetectable through the year in both groups of trout. In conclusion, the androgenic and oestrogenic profiles of sex-reversed XX males were similar to those observed in XY males. The only difference in the annual gonadal steroid cycle between XY and sex-reversed XX males was in the DHP profile.

  7. Wide spectrum of NR5A1‐related phenotypes in 46,XY and 46,XX individuals

    PubMed Central

    Domenice, Sorahia; Machado, Aline Zamboni; Ferreira, Frederico Moraes; Ferraz‐de‐Souza, Bruno; Lerario, Antonio Marcondes; Lin, Lin; Nishi, Mirian Yumie; Gomes, Nathalia Lisboa; da Silva, Thatiana Evelin; Silva, Rosana Barbosa; Correa, Rafaela Vieira; Montenegro, Luciana Ribeiro; Narciso, Amanda; Costa, Elaine Maria Frade; Achermann, John C

    2016-01-01

    Steroidogenic factor 1 (NR5A1, SF‐1, Ad4BP) is a transcriptional regulator of genes involved in adrenal and gonadal development and function. Mutations in NR5A1 have been among the most frequently identified genetic causes of gonadal development disorders and are associated with a wide phenotypic spectrum. In 46,XY individuals, NR5A1‐related phenotypes may range from disorders of sex development (DSD) to oligo/azoospermia, and in 46,XX individuals, from 46,XX ovotesticular and testicular DSD to primary ovarian insufficiency (POI). The most common 46,XY phenotype is atypical or female external genitalia with clitoromegaly, palpable gonads, and absence of Müllerian derivatives. Notably, an undervirilized external genitalia is frequently seen at birth, while spontaneous virilization may occur later, at puberty. In 46,XX individuals, NR5A1 mutations are a rare genetic cause of POI, manifesting as primary or secondary amenorrhea, infertility, hypoestrogenism, and elevated gonadotropin levels. Mothers and sisters of 46,XY DSD patients carrying heterozygous NR5A1 mutations may develop POI, and therefore require appropriate counseling. Moreover, the recurrent heterozygous p.Arg92Trp NR5A1 mutation is associated with variable degrees of testis development in 46,XX patients. A clear genotype‐phenotype correlation is not seen in patients bearing NR5A1 mutations, suggesting that genetic modifiers, such as pathogenic variants in other testis/ovarian‐determining genes, may contribute to the phenotypic expression. Here, we review the published literature on NR5A1‐related disease, and discuss our findings at a single tertiary center in Brazil, including ten novel NR5A1 mutations identified in 46,XY DSD patients. The ever‐expanding phenotypic range associated with NR5A1 variants in XY and XX individuals confirms its pivotal role in reproductive biology, and should alert clinicians to the possibility of NR5A1 defects in a variety of phenotypes presenting with gonadal

  8. Hurst exponent of very long birth time series in XX century Romania. Social and religious aspects

    NASA Astrophysics Data System (ADS)

    Rotundo, G.; Ausloos, M.; Herteliu, C.; Ileanu, B.

    2015-07-01

    The Hurst exponent of very long birth time series in Romania has been extracted from official daily records, i.e. over 97 years between 1905 and 2001 included. The series result from distinguishing between families located in urban (U) or rural (R) areas, and belonging (Ox) or not (NOx) to the orthodox religion. Four time series combining both criteria, (U,R) and (Ox, NOx), are also examined. A statistical information is given on these sub-populations measuring their XX-th century state as a snapshot. However, the main goal is to investigate whether the "daily" production of babies is purely noisy or is fluctuating according to some non trivial fractional Brownian motion, - in the four types of populations, characterized by either their habitat or their religious attitude, yet living within the same political regime. One of the goals was also to find whether combined criteria implied a different behavior. Moreover, we wish to observe whether some seasonal periodicity exists. The detrended fluctuation analysis technique is used for finding the fractal correlation dimension of such (9) signals. It has been first necessary, due to two periodic tendencies, to define the range regime in which the Hurst exponent is meaningfully defined. It results that the birth of babies in all cases is a very strongly persistent signal. It is found that the signal fractal correlation dimension is weaker (i) for NOx than for Ox, and (ii) or U with respect to R. Moreover, it is observed that the combination of U or R with NOx or OX enhances the UNOx, UOx, and ROx fluctuations, but smoothens the RNOx signal, thereby suggesting a stronger conditioning on religiosity rituals or rules.

  9. Reliability of high performance 9xx-nm single emitter laser diodes

    NASA Astrophysics Data System (ADS)

    Bao, Ling; Wang, Jun; Devito, Mark; Xu, Dapeng; Wise, Damian; Leisher, Paul; Grimshaw, Mike; Dong, Weimin; Zhang, Shiguo; Price, Kirk; Li, Daming; Bai, Chendong; Patterson, Steve; Martinsen, Rob

    2010-02-01

    This paper presents reliable high power and high brightness 9xx-nm single emitter laser diodes, which have been designed for various multi-emitter fiber-coupled modules. Diode lasers from legend generation have been life-tested with currents up to 14A at heat-sink and junction temperatures of 50°C and 80°C respectively, and have accumulated more than 15,000 hours of life-test duration. In order to further improve reliable operational power and optimize beam quality, new generation devices have been developed. The new devices demonstrated more than 20W CW rollover power without catastrophic optical mirror damage (COMD). Near-field/far-field patterns have also been improved significantly. In addition to step-stress life-tests, a 7-level multi-cell life-test was designed to investigate acceleration factors relative to the operation conditions. Junction temperatures ranging from 60°C to 110°C and current from 14A to 18A were used in this multi-cell life-test. The ongoing multi-cell life-test has accumulated 1.3 million raw device hours and shown very few device failures in up to 7000 hours duration. Such a low failure rate doesn't allow a meaningful estimation of acceleration factors. When nominal acceleration factors are used, multi-cell life-test data supports ~500 FIT, with 90% confidence, at 10W, 33°C/50°C heat-sink/junction temperatures.

  10. Male genitoplasty for 46 XX congenital adrenal hyperplasia patients presenting late and reared as males

    PubMed Central

    Sharma, Shilpa; Gupta, Devendra K.

    2012-01-01

    Aim: To evaluate the clinical profile and management of 46 XX Congenital Adrenal Hyperplasia (CAH) patients presenting with severe virilization and assigned a male gender. Materials and Methods: Of 173 children diagnosed with CAH at the Pediatric Intersex Clinic since 1980, seven children with CAH presented late with severe virilization and were reared as males. All of them were assigned the male sex with removal of the female adnexa. Six were treated with male genitoplasty. Appropriate hormonal supplementation was offered after puberty. Results: The mean age at presentation was 14.2 years (7 – 21). Six patients had presented after puberty, only one at seven years of age. Staged male genitoplasty comprising of chordee correction, male urethroplasty, and bilateral testicular prosthesis was performed. The female adnexa (uterus, ovaries, most of the upper vagina, and the fallopian tubes) were removed. The mental makeup was masculine in six and bigender in one. Bilateral mastectomy was performed at puberty in all. Hormonal treatment comprised of glucocorticoids and testosterone. Six patients were comfortable with the outcome of the masculinizing genitoplasty. One had a short-sized phallus. One had repeated attacks of urinary tract infection arising from the retained lower vaginal pouch. Social adjustments were good in all, except in one who had a bigender mental makeup. Conclusion: CAH patients with severe virilization presenting late and reared as males are extremely rare. However, the assigned gender can be retained adequately as males, meeting the socioeconomic compulsions of the society. The results are satisfactory following appropriate surgical procedures and hormonal supplementation. PMID:23226638

  11. Climate Change of Franz Josef Land in the XX-XXI Centuries

    NASA Astrophysics Data System (ADS)

    Shilovtseva, Olga; Romanenko, Fedor

    2016-04-01

    The results of climatic observations on the most northern land of Eurasia - Franz Josef Land, that was discovered in 1874, are presented. The gaps in the observations of the observatory named after Ernst Krenkel (Hayes's Island) were supplemented by calculations using reanalysis ERA Interim. It was received the positive trend in surface air temperature during 1958-2013. It is mainly achieved by increasing of the air temperature in winter but the summer trend is not statistically significant. Data of observation and reanalysis are perfectly correlated in cold period when underlying surface is uniform (correlation coefficient of more than 0.95). In summer, the correlation coefficients between the calculated and the real data are significantly lower (up to 0.68). This fact may be a consequence of the small values of the mean air temperatures of summer months (for example, during the July they varied in the interval -1-+2 degrees C.). Furthermore, it may be caused by the difficulty of model reproduction of the real state of the underlying surface, where land, ice, snow and water are chaotically combined. The analysis of circulation types by B.L. Dzerdzeevsky has shown that in the mid-XX Century, the northern meridional and western zonal types of circulation were replaced by southern meridional one, which prevailed during the first decade of the XXI too. This causes a reduction of the ice cover period, which resulted in a strengthening of the beach erosion and of slope processes. But short-term flows of warm air from the south, causing a catastrophic melting of glaciers, were also repeatedly marked in the past. This work is supported by the Russian Science Foundation (project № 14-37-00038) and by the national park "Russian Arctic".

  12. High power laser diodes at 14xx nm wavelength range for industrial and medical applications

    NASA Astrophysics Data System (ADS)

    Telkkälä, Jarkko; Boucart, Julien; Krejci, Martin; Crum, Trevor; Lichtenstein, Norbert

    2014-03-01

    We report on the development of the latest generation of high power laser diodes at 14xx nm wavelength range suitable for industrial applications such as plastics welding and medical applications including acne treatment, skin rejuvenation and surgery. The paper presents the newest chip generation developed at II-VI Laser Enterprise, increasing the output power and the power conversion efficiency while retaining the reliability of the initial design. At an emission wavelength around 1440 nm we applied the improved design to a variety of assemblies exhibiting maximum power values as high as 7 W for broad-area single emitters. For 1 cm wide bars on conductive coolers and for bars on active micro channel coolers we have obtained 50 W and 72 W in continuous wave (cw) operation respectively. The maximum power measured for a 1 cm bar operated with 50 μs pulse width and 0.01% duty cycle was 184 W, demonstrating the potential of the chip design for optimized cooling. Power conversion efficiency values as high as 50% for a single emitter device and over 40% for mounted bars have been demonstrated, reducing the required power budget to operate the devices. Both active and conductive bar assembly configurations show polarization purity greater than 98%. Life testing has been conducted at 95 A, 50% duty cycle and 0.5 Hz hard pulsed operation for bars which were soldered to conductive copper CS mounts using our hard solder technology. The results after 5500 h, or 10 million "on-off" cycles show stable operation.

  13. Torino 2006. XX Olympic and IX Paralympic Winter Games: the ENT experience

    PubMed Central

    Succo, G; Crosetti, E; Mattiazzo, A; Riontino, E; Massazza, G

    2008-01-01

    Summary A total of 27 competition days, more than 3000 athletes, over 10,000 components of the Olympic family, 3,500 workers, 2,500 volunteers, an overall business of more than 2 billion Euros. These, in a nutshell, are just a few of the data concerning the XX Olympic and the IX Paralympic Winter Games, Torino, Italy, 2006. Such a huge event, obviously required a meticulously organized medical service to cope with the healthcare of the athletes, official workers and the Olympic family, distributed over a geographic area of approximately 80 km in diameter. An ENT service was organized within the medical service, which was divided between 3 Polyclinics, in which 12 ENT Specialists were on duty. The present report gives an account of the final data concerning the service involved, together with a description of the approach used in the actual organization, with a view to providing useful information for colleagues who will be called upon, for a similar service, in future Olympic Winter Games. The ENT healthcare offered was confirmed to be proportional to the requirements, both from a qualitative and quantitative point of view. All the ENT specialists involved, reported having gained an immense store of human experience from having lived the Olympic atmosphere as a volunteer exerting one’s own profession. The facilities available in the Polyclinics, which were at a considerable distance from the Hospital, were found to be more than adequate with respect to the pathological conditions and service requested, particularly in 17% of the cases which would otherwise have been sent to a Hospital Outpatient Unit at least 80 km away. PMID:18646571

  14. The role of the sex-determining region Y gene in the etiology of 46,XX maleness

    SciTech Connect

    Fechner, P.Y.; Marcantonio, S.M.; Jaswaney, V.; Stetten, G.; Migeon, C.J.; Smith, K.D.; Berkovitz, G.D. ); Goodfellow, P.N. ); Amrhein, J.A. ); Bard, P.A. ); Lee, P.A. ); Reid, C. ); Tsalikian, E. ); Urban, M.D. )

    1993-03-01

    The condition of 46,XX maleness is characterized by testicular development in subjects who have two X chromosomes but who lack a normal Y chromosome. Several etiologies have been proposed to explain 46,XX maleness: (1) translocation of the testis-determining factor from the Y to the X chromosome, (2) mutation in an autosomal or X chromosome gene which permits testicular determination in the absence of TDF, and (3) undetected mosaicism with a Y-bearing cell line. The authors evaluated 10 affected subjects who were ascertained for different reasons and who had several distinct phenotypes. Six subjects had inherited sequences from the short arm of the Y chromosome including the sex-determining region Y gene (SRY). Five of the subjects were pubertal at the time of evaluation and had a phenotype similar to that of Klinefelter syndrome with evidence of Sertoli cell and Leydig cell dysfunction. One subject had evidence from Southern blot analysis and in situ hybridization for the presence of an intact Y chromosome in approximately 1% of cells. Three subjects lacked Y sequences by Southern blot analysis and by polymerase chain reaction amplification of SRY. These subjects were ascertained in the newborn period because of congenital anomalies. One had multiple anomalies including cardiac abnormalities; one had cardiac anomalies alone; and one had ambiguous genitalia. The data confirm the genetic heterogeneity of 46,XX maleness, in which some subjects have SRY while other subjects lack it. In addition, there is phenotypic heterogeneity among subjects who lack SRY suggesting that there is also genetic heterogeneity within this subgroup. 43 refs., 3 figs., 4 tabs.

  15. Ullrich-Turner phenotype with unusual manifestation in a patient with mosaicism 45,X/47,XX,+18

    SciTech Connect

    Franceschini, P.; Guala, A.; Camerano, P.; Franceschini, D.; Vardeu, M.P.; Signorile, F.

    1996-03-01

    We report on a girl with Ullrich-Turner phenotype and 45,X/47,XX,+18 chromosomal mosaicism. Only two other patients with similar mosaicism have been reported, both girls with XY sex chromosome constitution. The face of the patient was highly asymmetric, the right side being almost normal, the left showing a typical Ullrich-Turner syndrome appearance. This clinical impression was strengthened by photographic doubling of both hemifaces. The patient had normal intelligence and did not show any stigmata of trisomy 18. 13 refs., 2 figs., 1 tab.

  16. Autoimmune myelofibrosis accompanied by Sjögren's syndrome in a 47, XXX/46, XX mosaic woman.

    PubMed

    Takahashi, Tohru

    2014-01-01

    This report describes a patient with autoimmune myelofibrosis accompanied by Sjögren's syndrome (SS). A 36-year-old woman was admitted due to petechiae, purpura, gingival bleeding, dyspnea on exertion, and a lack of concentration. She had pancytopenia and was diagnosed with SS. A bone marrow study showed hypercellular marrow with reticulin fibrosis. Lymphocytic infiltrates and aggregates composed of a mixture of T and B cells in the marrow were also observed. A chromosomal analysis of the marrow cells showed 47, XXX and an analysis of peripheral lymphocytes revealed 47, XXX/46, XX mosaic results. The patient's cytopenia resolved following treatment with oral prednisolone.

  17. Molecular and cytogenetic studies in a case of XX SRY-negative sex reversal in an Arabian horse.

    PubMed

    Ciotola, F; Albarella, S; Pasolini, M P; Auletta, L; Esposito, L; Iannuzzi, L; Peretti, V

    2012-01-01

    An 18-month-old Arabian foal characterized by a stallion-like appearance was submitted for cytogenetic and molecular genetics examinations due to abnormalities of external genitalia and the presence of ovotestis-like structures in the abdominal cavity. By RB-banding the animal showed the normal female equine karyotype (2n = 64,XX). Molecular analysis revealed the absence of the SRY and ZFY genes and the presence of ZFX, a typical female equine condition. The entire RSPO1 coding region was examined to exclude its involvement. Although a SNP was found in exon 3, it was not responsible for an amino acid substitution.

  18. The Schrödinger System H=-12(tot)a∂xx+12ω2(tto)bX2

    NASA Astrophysics Data System (ADS)

    Nieto, Michael Martin; Truax, D. Rodney

    2001-08-01

    We attack the specific time-dependent Hamiltonian problem H=-12(tot)a∂xx+12ω2(tto)bx2. This corresponds to a time-dependent mass (TM) Schrödinger equation. We give the specific transformations to a different time-dependent quadratic Schrödinger equation (TQ) and to a different time-dependent oscillator (TO) equation. For each Schrödinger system, we give the Lie algebra of space-time symmetries, the number states, the squeezed-state and (with their classical motion), (Δx)2, (Δp)2, and the uncertainty product.

  19. The Metaphorical Applications of Heavenly Bodies and Phenomena in Western Armenian Poetry at the Beginning of the XX Century

    NASA Astrophysics Data System (ADS)

    Arakelyan, Karine

    2015-07-01

    The metaphorical applications of heavenly bodies and phenomena in Western Armenian poetry at the beginning of the XX century are very diverse and of great variety. Art Workers eulogize the creation of God, admire the beauty of stars, and perceive the man as a part of nature and in the close connection with all other parts. These units are often used for bringing to light one's inner life, his old gone paths, expectations and hopes, many times they become the heart and the basis of poetical image and create unique beauty.

  20. PREFACE: XX International School on Nuclear Physics, Neutron Physics and Applications (Varna2013)

    NASA Astrophysics Data System (ADS)

    Stoyanov, Chavdar; Dimitrova, Sevdalina

    2014-09-01

    The present volume contains the lectures and short talks given at the XX International School on Nuclear Physics, Neutron Physics and Applications. The School was held from 16-22 September 2013 in 'Club Hotel Bolero' located in 'Golden Sands' (Zlatni Pyasaci) Resort Complex on the Black Sea coast, near Varna, Bulgaria. The School was organized by the Institute for Nuclear Research and Nuclear Energy of Bulgarian Academy of Sciences. Co-organizer of the School was the Bulgarian Nuclear Regulatory Agency and the Bogoliubov Laboratory of Theoretical Physics of Joint Institute for Nuclear Research - Dubna. Financial support was also provided by the Bulgarian Ministry of Education and Science. According to the long-standing tradition the School has been held every second year since 1973. The School's program has been restructured according to our enlarged new international links and today it is more similar to an international conference than to a classical nuclear physics school. This new image attracts many young scientists and students from around the world. This year, 2013, we had the pleasure to welcome more than sixty distinguished scientists as lecturers. Additionally, twenty young colleagues received the opportunity to present a short contribution. Ninety-four participants altogether enjoyed the scientific presentations and discussions as well as the relaxing atmosphere at the beach and during the pleasant evenings. The program of the School ranged from latest results in fundamental areas such as nuclear structure and reactions to the hot issues of application of nuclear methods, reactor physics and nuclear safety. The main topics have been the following: Nuclear excitations at various energies. Nuclei at high angular moments and temperature. Structure and reactions far from stability. Symmetries and collective phenomena. Methods for lifetime measurements. Astrophysical aspects of nuclear structure. Neutron nuclear physics. Nuclear data. Advanced methods in

  1. Spanish Radiology in the second half of the XX Century: a view from inside.

    PubMed

    Bonmatí, José

    2008-09-01

    Radiology was born in 1896 with the immediate recognition of the diagnostic value of X-rays in medicine and progressed throughout the XX Century with the increasing knowledge of its properties and clinical applications. By mid-century Radiology was a respected clinical specialty in advanced countries, the radiological report was a requirement in hospital practice and radiologists' opinions requested in scientific meetings. In the last decades of the century has had a spectacular expansion with the emergence of new imaging modalities and revolutionary technologies that have transformed the specialty worldwide. In Spain Radiology lagged behind needs and demand in 1950. Radiological practice was unregulated and performance of X-ray exams by non-radiologists was common. Teaching of Radiology was non-existent in Medical Schools or postgraduation. The diagnostic value of the specialty was unrecognized by physicians and the role of radiologists ignored. Most hospital radiology services were poorly equipped and functionally inadequate. The shadow of the Civil War (1936-39) was conditioning Radiology in the country. The point of inflexion in the development of Radiology in Spain was the inclusion of film reading sessions in the 1965 academic program of the Society of Radiology. It was in the presentation of cases at these conferences that Clinical Radiology found the finest demonstration ground and as a result was immediately adopted by radiologists and progressively applied in scientific meetings, clinical practices and training programs. Its influence was important in reforming hospital practice, legislation on specialization and education, as well as in national health care plans. At the end of the century radiology in Spain was at a par with the standards of other western nations. The author was a witness of the evolution of Radiology during his 50 years of professional life. This article does not pretend to be exhaustive in names or contributions. It is an overview of

  2. 47,XX,+der(18),t(9;18)(p24;q21) mat: a distinct partial trisomy 18q--syndrome?

    PubMed Central

    Bass, H N; Weber-Parisi, F; Sparkes, R S

    1978-01-01

    A moderately retarded girl had a 47,XX,+der(18),t(9;18)(p24;q21)mat abnormality that was inherited from her mother, who had a 46,XX,t(9;18)(p24;q21) karyotype in most cells, and a minor cell line of 47,XX,+der(18),-t(9;18)(p24;q21). Her dysmorphic features--bilateral epicanthic folds, low-set, abnormal ears, low posterior hairline, clinodactyly of the 5th fingers, and broad great toes--were similar to those of other patients with an additional number 18 chromosome in which all or most of the long arm was missing, thus raising the possibility of a distinct syndrome. Images PMID:739531

  3. Gender Role, Gender Identity and Sexual Orientation in CAIS ("XY-Women") Compared With Subfertile and Infertile 46,XX Women.

    PubMed

    Brunner, Franziska; Fliegner, Maike; Krupp, Kerstin; Rall, Katharina; Brucker, Sara; Richter-Appelt, Hertha

    2016-01-01

    The perception of gender development of individuals with complete androgen insensitivity syndrome (CAIS) as unambiguously female has recently been challenged in both qualitative data and case reports of male gender identity. The aim of the mixed-method study presented was to examine the self-perception of CAIS individuals regarding different aspects of gender and to identify commonalities and differences in comparison with subfertile and infertile XX-chromosomal women with diagnoses of Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS) and polycystic ovary syndrome (PCOS). The study sample comprised 11 participants with CAIS, 49 with MRKHS, and 55 with PCOS. Gender identity was assessed by means of a multidimensional instrument, which showed significant differences between the CAIS group and the XX-chromosomal women. Other-than-female gender roles and neither-female-nor-male sexes/genders were reported only by individuals with CAIS. The percentage with a not exclusively androphile sexual orientation was unexceptionally high in the CAIS group compared to the prevalence in "normative" women and the clinical groups. The findings support the assumption made by Meyer-Bahlburg ( 2010 ) that gender outcome in people with CAIS is more variable than generally stated. Parents and professionals should thus be open to courses of gender development other than typically female in individuals with CAIS.

  4. Cytogenetic Investigation in a Group of Ten Infertile Men with Non-Obstructive Azoospermia: First Algerian 46, XX Syndrome

    PubMed Central

    BAZIZ, Meriem; HAMOULI-SAID, Zohra; RATBI, Ilham; HABEL, Mohamed; GUAOUA, Soukaina; SBITI, Aziza; SEFIANI, Abdelaziz

    2016-01-01

    Background: In Algeria, the data on infertility and its various causes are rare. Recently, the introduction of assisted reproduction has allowed expecting that 300000 couples, which represent 7% of couples of reproductive age, face difficulty conceiving a child. Knowing that most idiopathic cases are likely to be due to chromosomal abnormalities, we aimed to investigate genetic defects by karyotype analysis in Algerian infertile men, using peripheral blood lymphocytes. Methods: A cytogenetic study was conducted on 10 men from infertile couples by Karyotype analysis of R-banding performed by lymphocyte culture technique. Fluorescence in situ hybridization was performed and molecular abnormalities were investigated by polymerase chain reaction. Follicle stimulating hormone (FSH) and luteinizing hormone (LH) levels were evaluated by immunoradiometric method. Results: Chromosomal abnormalities were observed in 30% of the patients. We identified a homogenous Klinefelter syndrome patient with 47, XXY karyotype, a mosaic Klinefelter syndrome patient with 47, XXY/46, XY karyotype and a 46, XX male. Fluorescence in situ hybridization showed that the sex-determining region Y was translocated to the short arm of the X chromosome in patient with 46, XX chromosomal constitution and the presence of the SRY gene was confirmed by polymerase chain reaction and electrophoresis. Conclusion: The occurrence of chromosomal abnormalities in 30% of the infertile men strongly supports the inclusion of routine cytogenetic testing for diagnostic establishment and suitable counseling for couples seeking for assisted reproduction technologies. PMID:27648416

  5. Vegetation Structure Changes in the South Part of Western Siberia at the End of XX Century

    NASA Astrophysics Data System (ADS)

    Dyukarev, E.; Pologova, N. N.; Golovatskaya, E. A.; Dyukarev, A. G.; Gordov, E. P.; Okladnikov, I. G.; Titov, A. G.

    2010-12-01

    Understanding human impact on changes in vegetation composition and structure can be performed using analysis of space images obtained from high resolution satellite sensors. Natural ecosystems at the South and Sob-Taiga zone of Western Siberia are characterized by development of an early succession stages, given the projected increase in disturbance, or will be converted into human-dominated terrestrial production systems. Disturbances appear to be increasing in some regions, leading to fragmentation of natural ecosystems and to a generally "weedier," structurally simpler biosphere with fewer systems in a more ecologically complex old-growth state. The analysis of structure of vegetation cover at two test sites located at the south-west part of the West-Siberian Plain in the South and Sub-Taiga zone was made using LANDSAT space images and ground data obtained in various seasons and years. The studied area of the first test site (“Bakchar”) is occupied by bogs, paludificated forests and cultivated lands. Test site “Tomsk” covered by cultivated lands and dark coniferous forest complexes. Vegetation classification was made using NELDA project legend (www.fsl.orst.edu/nelda). The main part of Site “Bakchar” is occupied by tree dominated classes (66%). Wetlands occupy about 43% of the area. Part of herbaceous vegetation is rather low (9%). Site “Tomsk” has completely different structure of classes. More than one-half of the area (52%) is covered by cultivated lands. Forests occupy 42% of the area. Wetlands (9%) exist in the Ob’-Tom’ interfluve and left bank of the Ob’ river. During the XX century the vegetation cover was exposed to natural and anthropogenic changes. Comparison of space images from different years (1990, 1999 and 2007) allowed to reveal dynamics in vegetation cover. Decrease of forest area in 1990-1999 at site “Bakchar” are primary occurs due to intense forest cutting for timber industry and local use. A strong wind have

  6. A rare mosaic interstitial deletion of 7q, 46,XX/46,XX,del(7)(q22.1q31.33), results in a mild clinical phenotype

    SciTech Connect

    Shapira, S.K.; Kochanek, S.; Shaffer, L.G.

    1994-09-01

    Constitutional mosaic structural rearrangements, including deletions, are extremely rare in the population. We present a case of mosaicism for a deletion of chromosome 7q. The patient`s phenotype is much milder than that of non-mosaic patients with a similar deletion of 7q. A 6 and 9/12-year-old Caucasian girl was evaluated because of attention deficit disorder and speech delay. She was born at 38 weeks gestation to her 37 year old G2P2 mother. Her birth weight was 2.2 kg (3rd centile), length was 47 cm (10th-25th centile), and OFC was 30.5 cm (<10th centile). Her motor development was normal. Her speech development was profoundly delayed with her first words spoken at 3 years, and 2-3 word sentences spoken at 5-6 years. At 6 and 9/12 years, she manifested mild mental retardation and profound speech delay, but only mildly dysmorphic features (protuberant ears with under-developed antihelices, flattened forehead, moderate micro-retrognathia). Height, weight, and OFC were at the 10th centile. Chromosomal analysis showed the presence of two cell lines, with 66% of the lymphocytes having a 46,XX pattern and 33% having a 46,XX,del(7)(q22.1q31.33) karyotype. Less than 20 cases of interstitial 7q deletions extending from bands 7q21 or 7q22 to 7q31 or 7q32 have been reported. Our patient represents the first documented case with a mosaic interstitial deletion of chromosome 7q. Furthermore, the deletion resulted in a relatively mild phenotype when compared to reported non-mosaic interstitial 7q deletions, and thus expands the range of clinical heterogeneity that can be anticipated in interstitial deletion patients.

  7. Semiempirical calculation of radiative constants in the spectra of nickel-like ions Kr IX, Sr XI, Y XII, Ru XVII, Pd XIX, and Ag XX

    NASA Astrophysics Data System (ADS)

    Loginov, A. V.

    2015-03-01

    The probabilities of the electric-dipole transitions 3 d 94 p, 3 d 94 f-3 d 10, 3 d 94 s, and 3 d 94 d in the spectra of nickel-like ions Kr IX, Sr XI, Y XII, Ru XVII, Pd XIX, and Ag XX are calculated semiempirically with the use of published energy levels.

  8. [Apparent internal male pseudo-hermaphroditism. Gynecomastia. Negative gonad surgical research. Caryotype 46, XX. Presence of H-Y antigen (author's transl)].

    PubMed

    Vague, J; Guidon, J; Mattei, J F; Luciani, J M; Jouve, R; Le Gall, F

    1977-01-01

    Boy 15. Aspect of delayed puberty with empty scrotum and gynecomastia. Caryotype 46, XX. Presence of H.Y. Antigen. Plasmatic testosterone 1 020 pg/ml. Normal plasmatic FSH and LH. Hypotrophic uterus and tubes. No gonad found. Small right epididymis. Complete virilization by testosterone.

  9. Sox10 gain-of-function causes XX sex reversal in mice: implications for human 22q-linked disorders of sex development.

    PubMed

    Polanco, Juan Carlos; Wilhelm, Dagmar; Davidson, Tara-Lynne; Knight, Deon; Koopman, Peter

    2010-02-01

    Male development in mammals is normally initiated by the Y-linked gene Sry, which activates expression of Sox9, leading to a cascade of gene activity required for testis formation. Although defects in this genetic cascade lead to human disorders of sex development (DSD), only a dozen DSD genes have been identified, and causes of 46,XX DSD (XX maleness) other than SRY translocation are almost completely unknown. Here, we show that transgenic expression of Sox10, a close relative of Sox9, in gonads of XX mice resulted in development of testes and male physiology. The degree of sex reversal correlated with levels of Sox10 expression in different transgenic lines. Sox10 was expressed at low levels in primordial gonads of both sexes during normal mouse development, becoming male-specific during testis differentiation. SOX10 protein was able to activate transcriptional targets of SOX9, explaining at a mechanistic level its ability to direct male development. Because over-expression of SOX10 alone is able to mimic the XX DSD phenotypes associated with duplication of human chromosome 22q13, and given that human SOX10 maps to 22q13.1, our results functionally implicate SOX10 in the etiology of these DSDs.

  10. 49 CFR 1242.73 - Cleaning car interiors and freight lost and damaged-all other (accounts XX-53-70 and 51-53-00).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Cleaning car interiors and freight lost and damaged-all other (accounts XX-53-70 and 51-53-00). 1242.73 Section 1242.73 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) ACCOUNTS, RECORDS AND...

  11. What Does f[subscript xx]f[subscript yy] - f[superscript 2][subscript xy] Greater than 0 "Really" Mean?

    ERIC Educational Resources Information Center

    McCartin, Brian J.

    2008-01-01

    This note presents geometric and physical interpretations of the sufficient condition for a critical point to be a strict relative extremum: f[subscript xx]f[subscript yy] - f[superscript 2][subscript xy] greater than 0. The role of the double derivative f[subscript xy] in this inequality will be highlighted in these interpretations. (Contains 14…

  12. An ab initio approach on superconducting properties of Mo3X(X = Si,Ga,Ge) compounds

    NASA Astrophysics Data System (ADS)

    Subhashree, G.; Sankar, S.; Krithiga, R.

    2015-06-01

    Self-consistent first principles calculations on type II weakly coupled superconducting Mo3X(X = Si,Ga,Ge) compounds of A15 phase are performed to understand their fundamental characteristics of the electronic, thermal and superconducting properties. The bulk modulus (B), Debye temperature (θD), density of states (DOS) (N(EF)), electron-phonon coupling constant (λ), superconducting transition temperature (Tc), and electronic specific heat coefficient (γ) have been computed in terms of the electronic structure results, obtained by using the tight-binding linear muffin-tin orbital method. It is observed that all the three materials have their electronic properties dominated by d-orbital at Fermi energy. Thermal and superconducting properties calculated here are found to corroborate well with the experimental results of literature.

  13. 76 FR 22830 - Airworthiness Directives; Sicma Aero Seat 88xx, 89xx, 90xx, 91xx, 92xx, 93xx, 95xx, and 96xx...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-25

    ...; telephone 33 (0) 2 54 03 39 39; fax 33 (0) 2 54 03 39 00; e-mail: customerservices@sicma.zodiac.com ; Internet http://www.sicma.zodiac.com/en/ . You may review copies of the referenced service information...

  14. 75 FR 2826 - Airworthiness Directives; Sicma Aero Seat 88xx, 89xx, 90xx, 91xx, 92xx, 93xx, 95xx, and 96xx...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-19

    ..., France; telephone 33 (0) 2 54 03 39 39; fax 33 (0) 2 54 03 39 00; e-mail: customerservices@sicma.zodiac.com ; Internet: http://www.sicma.zodiac.com/en/ . You may review copies of the referenced...

  15. The study of the hydrological regime extreme effects of the Caspian Sea during the XX-XXI centuries

    NASA Astrophysics Data System (ADS)

    Yaitskaya, Natalia

    2016-04-01

    The Caspian Sea - the unique largest enclosed inland body of water on Earth. Significant periodic sea level fluctuations are a typical feature of the sea. In the XIX-XX centuries a number of comprehensive studies of the Caspian Sea was carried out. The results are published in the papers, monographs and climatic atlases. But a number of fundamental questions about the features of the hydrological regime of the Caspian Sea is still open: 1. How does the water circulation change during the level variations? 2. What is the effect of heterogeneity of evaporation from the water surface on the formation of the flow field in the conditions of long-term level changes? 3. How does the water salinity regime change depending on the sea level position, water circulation, river flow and different climatic influences? 4. What is the effect of extreme events (multi-hazards) (ice, storms, destruction of the coasts) on coastal infrastructure? In 2016, the project aims to study hydrological regime extreme effects of the Caspian Sea was supported by the Russian Foundation for Basic Research. Within this project all of the above problems will be solved. Geographic information system "Caspian Sea" for the storage and data processing, including a database of primary oceanographic information for the period of instrumental observations (1897-2013), cartographic database (1921-2011) and tools for multidimensional analysis of spatio-temporal information is the basis of the study. The scheme of interconnected hydrodynamic models (Caspian Sea MODel - Ocean Model - Wind wave model) was developed. The important factors are taken into account in the structure of the models: long-term and seasonal dynamics of the sea waves parameters, new long-term values of evaporation from the shallow waters areas of the Caspian Sea, water circulation. Schemes of general seasonal circulation of the Caspian Sea and the Northern Caspian at different positions of the sea level in XX-XXI centuries using

  16. High resolution X-ray spectra of solar flares. V - Interpretation of inner-shell transitions in Fe XX-Fe XXIII

    NASA Technical Reports Server (NTRS)

    Doschek, G. A.; Feldman, U.; Cowan, R. D.

    1981-01-01

    The paper examines high-resolution solar flare iron line spectra recorded between 1.82 and 1.97 A by a spectrometer flown by the Naval Research Laboratory on an Air Force spacecraft launched on 1979 February 24. The emission line spectrum is due to inner-shell transitions in the ions Fe XX-Fe XXV. Using theoretical spectra and calculations of line intensities obtained by methods discussed by Merts, Cowan, and Magee (1976), electron temperatures as a function of time for two large class X flares are derived. These temperatures are deduced from intensities of lines of Fe XXII, Fe XXIII, and Fe XXIV. The determination of the differential emission measure between about 12-million and 20-million K using these temperatures is considered. The possibility of determining electron densities in flare and tokamak plasmas using the inner-shell spectra of Fe XXI and Fe XX is discussed.

  17. Dose distribution analysis of physical and dynamic wedges by using an intensity-modulated radiotherapy MatriXX

    NASA Astrophysics Data System (ADS)

    Lee, Hae-Kag; Cho, Jae-Hwan; Cho, Dae-chul

    2013-05-01

    This study investigated differences between the physical wedge and the dynamic wedge distributions of radiation by using an intensity-modulated radiotherapy (ImRT) MatriXX. The linear accelerator used X-rays with energy levels of 6 MV and 10 MV to adjust the collimator by motoring the independent jaws (X1, X2, Y1, Y2) for setting wedge angles of 15, 30, 45, and 60 degrees. The collimator field size was set as 10 × 10 cm2 or 20 × 20 cm2 at the maximum dose point. The dose distribution for each wedge had ±5% and ±11% errors for field sizes of 10 × 10 cm2 and 20 × 20 cm2, respectively. The error was greatest at a wedge angle of 45 degrees and was pronounced at the end of the dynamic wedge where Y1 and Y2 met. Consequently, concluded that the dose distributions were similar for both wedges for the field size of a small beam profile. The beam dose was greatly increased at the end of the dynamic wedge. A more precise estimate of the therapeutic dose of radiation for a dynamic wedge that nearly matches that of the physical wedge can be achieved by correcting of the increasing part of the beam dose. The findings imply that a heavy wedge filter should not be used when calculating the isodose distribution and the therapeutic dose.

  18. Advances in performance and beam quality of 9xx-nm laser diodes tailored for efficient fiber coupling

    NASA Astrophysics Data System (ADS)

    Lauer, Christian; König, Harald; Grönninger, Günther; Hein, Sebastian; Gomez-Iglesias, Alvaro; Furitsch, Michael; Maric, Josip; Kissel, Heiko; Wolf, Paul; Biesenbach, Jens; Strauss, Uwe

    2012-03-01

    The impact of new direct-diode and fiber laser systems on industrial manufacturing drives the demand for highbrightness diode laser pump sources suitable for simple fiber coupling with high efficiency. Within the German funded project HEMILAS laser mini-bars with different bar geometries and small fill factors were investigated. We present results on 9xx nm bars with tailored beam parameter products for simplified coupling to fibers with core diameters of 200μm and 300μm with a numerical aperture of 0.22 and compare beam quality parameters, brightness, conversion efficiency, and thermal performance of different bar designs. Optimized epitaxy structures yield conversion efficiency maxima above 66%. The slow axis divergence angle of mini-bars with a fill factor of 10% featuring five 100μm wide and 4mm long emitters based on this epitaxy structure stays below 7°, which corresponds to a beam parameter product of 15mm mrad, up to very high output power of over 45W. This result was achieved for mounting on actively cooled submounts using hard solder. A similar bar with 5mm cavity length and using soft soldering reached an output power of 60W at the same beam parameter product. At 4mm cavity length, no COMD failures were observed up to currents exceeding the thermal rollover and the maximum output cw power was 95W.

  19. Identification by FISH of 21q22 duplication in patient with Down syndrome and apparent 46,XX karyotype

    SciTech Connect

    Yu, Chih-yu; Anyane-Yeoba, K.; Warburton, D.

    1994-09-01

    Karyotype analysis of a 3-day-old child referred for clinical evaluation of Down syndrome was originally reported as normal 46,XX. The child had many features of Down syndrome, including a leukemoid reaction at birth. Because of the strongly suggestive clinical features, and a slightly unusual appearance of the short arm of one chromosome 21, FISH analysis was carried out using a probe specific for the 21q22.3 region (ONCOR). Signal was seen as expected in the distal long arm of both chromosomes 21, but also in the short arm with the morphological variant. DNA analysis with a number of long arm probes confirmed the presence of duplication of a large portion of band 21q22. Parental karyotypes were normal. The mother of this case had declined amniocentesis. However, it is very likely that routine prenatal chromosome analysis would not have detected the duplication, since the short arm was not strikingly different from many normal variants. Only screening with a 21q22 FISH probe (interphase or metaphase) would have predicted the Down syndrome in this child.

  20. XX/XO, a rare sex chromosome system in Potamotrygon freshwater stingray from the Amazon Basin, Brazil.

    PubMed

    de Souza Valentim, Francisco Carlos; Porto, Jorge Ivan Rebelo; Bertollo, Luiz Antonio Carlos; Gross, Maria Claudia; Feldberg, Eliana

    2013-09-01

    Potamotrygonidae is a representative family of South American freshwater elasmobranchs. Cytogenetic studies were performed in a Potamotrygon species from the middle Negro River, Amazonas, Brazil, here named as Potamotrygon sp. C. Mitotic and meiotic chromosomes were analyzed using conventional staining techniques, C-banding, and detection of the nucleolus organizing regions (NOR) with Silver nitrate (Ag-NOR). The diploid number was distinct between sexes, with males having 2n = 67 chromosomes, karyotype formula 19m + 8sm + 10st + 30a, and fundamental number (FN) = 104, and females having 2n = 68 chromosomes, karyotype formula 20m + 8sm + 10st + 30a, and FN = 106. A large chromosome, corresponding to pair number two in the female karyotype, was missing in the male complement. Male meiotic cells had 33 bivalents plus a large univalent chromosome in metaphase I, and n = 33 and n = 34 chromosomes in metaphase II. These characteristics are consistent with a sex chromosome system of the XX/XO type. Several Ag-NOR sites were identified in both male and female karyotypes. Positive C-banding was located only in the centromeric regions of the chromosomes. This sex chromosome system, which rarely occurs in fish, is now being described for the first time among the freshwater rays of the Amazon basin.

  1. Energy levels, oscillator strengths, and radiative rates for Si-like Zn XVII, Ga XVIII, Ge XIX, and As XX

    SciTech Connect

    Abou El-Maaref, A.; Allam, S.H.; El-Sherbini, Th.M.

    2014-01-15

    The energy levels, oscillator strengths, line strengths, and transition probabilities for transitions among the terms belonging to the 3s{sup 2}3p{sup 2}, 3s3p{sup 3}, 3s{sup 2}3p3d, 3s{sup 2}3p4s, 3s{sup 2}3p4p and 3s{sup 2}3p4d configurations of silicon-like ions (Zn XVII, Ga XVIII, Ge XIX, and As XX) have been calculated using the configuration-interaction code CIV3. The calculations have been carried out in the intermediate coupling scheme using the Breit–Pauli Hamiltonian. The present calculations have been compared with the available experimental data and other theoretical calculations. Most of our calculations of energy levels and oscillator strengths (in length form) show good agreement with both experimental and theoretical data. Lifetimes of the excited levels have also been calculated. -- Highlights: •We have calculated the fine-structure energy levels of Si-like Zn, Ga, Ge and As. •The calculations are performed using the configuration interaction method (CIV3). •We have calculated the oscillator strengths, line strengths and transition rates. •The wavelengths of the transitions are listed in this article. •We also have made comparisons between our data and other calculations.

  2. Proceedings of the Twentieth NASA Propagation Experimenters Meeting (NAPEX XX) and the Advanced Communications Technology Satellite (ACTS) Propagation Studies Miniworkshop

    NASA Technical Reports Server (NTRS)

    Golshan, Nassar (Editor)

    1996-01-01

    The NASA Propagation Experimenters (NAPEX) Meeting and associated Advanced Communications Technology Satellite (ACTS) Propagation Studies Miniworkshop convene yearly to discuss studies supported by the NASA Propagation Program. Representatives from the satellite communications (satcom)industry, academia, and government with an interest in space-ground radio wave propagation have peer discussion of work in progress, disseminate propagation results, and interact with the satcom industry. NAPEX XX, in Fairbanks, Alaska, June 4-5, 1996, had three sessions: (1) "ACTS Propagation Study: Background, Objectives, and Outcomes," covered results from thirteen station-years of Ka-band experiments; (2) "Propagation Studies for Mobile and Personal Satellite Applications," provided the latest developments in measurement, modeling, and dissemination of propagation phenomena of interest to the mobile, personal, and aeronautical satcom industry; and (3)"Propagation Research Topics," covered a range of topics including space/ground optical propagation experiments, propagation databases, the NASA Propagation Web Site, and revision plans for the NASA propagation effects handbooks. The ACTS Miniworkshop, June 6, 1996, covered ACTS status, engineering support for ACTS propagation terminals, and the ACTS Propagation Data Center. A plenary session made specific recommendations for the future direction of the program.

  3. Magnetoelectric effects in the spin 1/2 XX chain with three spin interactions and Dzyaloshinskii-Moriya interaction

    NASA Astrophysics Data System (ADS)

    Durganandini, P.

    We consider the spin 1/2 XX chain with three spin interactions of the XZX+YXY and XZY-YZX types in an external magnetic field and with Dzyaloshinskii-Moriya (D-M) interaction. Interpreting the D-M interaction as a local electric polarization, we study the magnetoelectric effects in the system by using the exact solution of the problem. We obtain the ground state phase diagram by calculating the electric polarization, magnetization and isentropes. There are various regimes of magnetic and electric polarization depending on the relative strengths of the three spin interaction as well as that of the external fields. For a certain range of three spin interaction strengths, the system shows the existence of finite magnetization and electric polarization even in the absence of any external fields. The external electric and magnetic fields modify the ground state phases and can be used to tune the various regimes. We also calculate the entropy and analyze the electrocaloric and magnetocaloric effects. We show that the electrocaloric and magnetocaloric effects can be used to obtain information about the magnetoelectric effects in the system. I thank DST, India for financial support through research grant.

  4. Review of Outcome Information in 46,XX Patients with Congenital Adrenal Hyperplasia Assigned/Reared Male: What Does It Say about Gender Assignment?

    PubMed

    Lee, Peter A; Houk, Christopher P

    2010-01-01

    There is ample historical verification of 46,XX congenital adrenal hyperplasia (CAH) patients being born with essentially male genitaliawhile outcome information is scant. Prior to glucocorticoid therapy, most patients died very young from adrenal insufficiency. Most available reports from laterchildhood, contain little information concerning sexual identity. Reports on older individuals lack adequate information about sexual identity and quality of life. The difficulty in assessing the relative impact of multiple dynamic environmental factors on the development of sexual identity, self- and body esteem and overall adjustment to life is clear. Nevertheless, it remains unclear whether those infants whose masculine genitalia at birth resulted in an initial male assignment would have enjoyed a better adult outcome had they been allowed to remain male rather than the female reassignment that most received. Further, one could ask whether a male sex of rearing should be considered in 46,XX CAH infants with male external genitalia. After reviewing available literature, we conclude that because those extremely virlized 46,XX CAH patients who were reared male with healthy social support demonstrated satisfactory levels of social and sexual function as adults a male sex assignment should be considered in these types of infants when social and cultural environment are supportive.

  5. Chromosome analysis in Pseudopaludicola (Anura, Leiuperidae), with description of sex chromosomes XX/XY in P. saltica.

    PubMed

    Duarte, Thiago C; Veiga-Menoncello, Ana Cristina P; Lima, Janaína F R; Strüssmann, Christine; Del-Grande, Maria L; Giaretta, Ariovaldo A; Pereira, Emiliane G; Rossa-Feres, Denise C; Recco-Pimentel, Shirlei M

    2010-04-01

    Taxonomic changes have frequently occurred in the anuran genus Pseudopaludicola as a consequence of high morphological similarity among its species. The present work reports karyotypic analysis of three Pseudopaludicola species sampled in their type locality and four Pseudopaludicola populations from distinct localities, aiming at contributing to the systematics of this genus. Chromosomes were stained with Giemsa or submitted to the silver staining (Ag-NOR) and C-banding techniques. The karyotype was 2n=22 in P. mineira, Pseudopaludicola sp. and two populations of P. saltica. The chromosome pair 8 was heteromorphic in P. saltica, characterizing a XX/XY sex-determination system with telocentric X and submetacentric Y. Highly similar karyotypes with 2n=18 chromosomes were observed in P. canga, P. aff. canga from Barreirinhas, State of Maranhão, Uberlândia, State of Minas Gerais and Icém, State São Paulo. The high similarity among the karyotypes 2n=18 suggested that the populations of P. aff. canga belong to the group 'pusilla', the same group of P. canga. The data demonstrated also that P. aff. canga from Barreirinhas (northeast region) is cytogenetically identical to P. canga with regarding the NOR site position in pair 3 and the presence of a heterochromatic block in the pair 2, whereas P. aff. canga from Uberlândia and Icém (southeast) had the NOR in the pair 9. Moreover, the cytogenetic data discriminated P. mineira and Pseudopaludicola sp. from the previously analyzed species with 22 chromosomes, and suggested that Pseudopaludicola sp. is an undescribed species. Sexual heteromorphic chromosomes are firstly reported in Pseudopaludicola and the data indicated the need of an extensive taxonomic review in this genus.

  6. SU-E-T-413: Examining Acquisition Rate for Using MatriXX Ion Chamber Array to Measure HDR Brachytherapy Treatments

    SciTech Connect

    Wagar, M; Bhagwat, M; O’Farrell, D; Friesen, S; Buzurovic, I; Damato, A; Devlin, P; Cormack, R

    2015-06-15

    Purpose: There are unique obstacles to implementing the MatriXX ionchamber array as a QA tool in Brachytherapy given that the device is designed for use in the MV energy range. One of the challenges we investigate is the affect of acquisition rates on dose measurement accuracy for HDR treatment plans. Methods: A treatment plan was optimized in Oncentra Brachy TPS to deliver a planar dose to a 5×5cm region at 10mm depth. The applicator was affixed to the surface of the MatriXX array. The plan was delivered multiple times using a Nucleatron HDR afterloader with a 2.9Ci Ir192 source. For each measurement the sampling rate of the MatriXX movie mode was varied (30ms and 500ms). This experiment was repeated with identical parameters, following a source exchange, with an 11.2Ci Ir192 source. Finally, a single snap measurement was acquired. Analysis was preformed to evaluate the fidelity of the dose delivery for each iteration of the experiment. Evaluation was based on the comparison between the measured and TPS predicted dose. Results: Higher sample rates induce a greater discrepancy between the predicted and measured dose. Delivering the plan using a lower activity source also produced greater discrepancy in the measurement due to the increased delivery time. Analyzing the single snap measurement showed little difference from the 500ms integral dose measurement. Conclusion: The advantage of using movie mode for HDR treatment delivery QA is the ability for real time source tracking in addition to dose measurement. Our analysis indicates that 500ms is an optimal frame rate.

  7. Normal growth and normalization of hypergonadotropic hypogonadism in atypical Turner syndrome (45,X/46,XX/47,XXX). Correlation of body height with distribution of cell lines.

    PubMed

    Partsch, C J; Pankau, R; Sippell, W G; Tolksdorf, M

    1994-06-01

    A comparison has been made of a case with 45,X/46,XX/47,XXX mosaicism with some 50 cases in the literature. A significant positive correlation was found between height standard deviation scores of mosaic patients from the literature and the frequency of cells with a normal chromosome constitution (n = 21, rs = 0.552, P < 0.01). In contrast, a significant negative correlation was seen between body height and the frequency of cells with a 45,X constitution (n = 21, rs = -0.594, P < 0.01). There was no significant correlation of height standard deviation score with the 47,XXX cell line (n = 21, rs = -0.353). A patient with a rare chromosomal mosaicism (45,X/46,XX/47,XXX) is described. The diagnosis was first made by chromosome analysis in amniotic cells. The patient showed no symptoms suggestive of Turner syndrome and growth followed the 75th height percentile. Basal and gonadotropin-releasing hormone stimulated gonadotropin levels normalized after age 4.8 years and did not subsequently return to hypergonadotropic levels. In blood lymphocytes, there was an increase in the frequency of cells with a normal chromosome constitution over 9 years. This in vivo cell selection is discussed. Chromosome analysis in skin fibroblasts showed the same triple mosaicism with a similar distribution of cell lines as in blood lymphocytes. In conclusion, statistical evidence was demonstrated that the severity of short stature is correlated with the distribution of cell lines in 45,X/46,XX/47,XXX mosaicism. This finding is of importance for the genetic counselling in cases of prenatal diagnosis of mosaic Turner syndrome.

  8. Hypospadias in a male (78,XY; SRY-positive) dog and sex reversal female (78,XX; SRY-negative) dogs: clinical, histological and genetic studies.

    PubMed

    Switonski, M; Payan-Carreira, R; Bartz, M; Nowacka-Woszuk, J; Szczerbal, I; Colaço, B; Pires, M A; Ochota, M; Nizanski, W

    2012-01-01

    Hypospadias is rarely reported in dogs. In this study we pre-sent 2 novel cases of this disorder of sexual development and, in addition, a case of hereditary sex reversal in a female with an enlarged clitoris. The first case was a male Moscow watchdog with a normal karyotype (78,XY) and the presence of the SRY gene. In this dog, perineal hypospadias, bilateral inguinal cryptorchidism and testes were observed. The second case, representing the Cocker spaniel breed, had a small penis with a hypospadic orifice of the urethra, bilateral cryptorchidism, testis and a rudimentary gonad inside an ovarian bursa, a normal female karyotype (78,XX) and a lack of the SRY gene. This animal was classified as a compound sex reversal (78,XX, SRY-negative) with the hypospadias syndrome. The third case was a Cocker spaniel female with an enlarged clitoris and internally located ovotestes. Cytogenetic and molecular analyses revealed a normal female karyotype (78,XX) and a lack of the SRY gene, while histology of the gonads showed an ovotesticular structure. This case was classified as a typical hereditary sex reversal syndrome (78,XX, SRY-negative). Molecular studies were focused on coding sequences of the SRY gene (case 1) and 2 candidates for monogenic hypospadias, namely MAMLD1 (mastermind-like domain containing 1) and SRD5A2 (steroid-5-alpha-reductase, alpha polypeptide 2). Sequencing of the entire SRY gene, including 5'- and 3'-flanking regions, did not reveal any mutation. The entire coding sequence of MAMLD1 and SRD5A2 was analyzed in all the intersexes, as well as in 4 phenotypically normal control dogs (3 females and 1 male). In MAMLD1 2 SNPs, including 1 missense substitution in exon 1 (c.128A>G, Asp43Ser), were identified, whereas in SRD5A2 7 polymorphisms, including 1 missense SNP (c.358G>A, Ala120Thr), were found. None of the identified polymorphisms cosegregated with the intersexual phenotype, thus, we cannot confirm that hypospadias may be associated with polymorphism

  9. Hormonal studies in a male with a 47,XXX chromosome constitution: comparison with the hormonal pattern of a 46,XX male and patients with Klinefelter's syndrome.

    PubMed

    Borghi, A; Forti, G; Fusi, S; Bigozzi, U; Giusti, G

    1980-01-01

    Chromosome analysis in peripheral blood lymphocytes and skin fibroblasts of a 18 year old chromatin-positive man showed a 47,XXX karyotype. The following hormonal studies were performed: 1) FSH and LH response to GnRH; 2) hypothalamic-pituitary responsiveness to short-term testosterone administration; 3) plasma levels of testosterone, dihydrotestosterone, 17-hydroxyprogesterone, estradiol before and after hCG stimulation. Results were compared with similar studies performed in a 46,XX male and in a group of patients with Klinefelter's syndrome. Our data support the hypothesis that this rare cytogenetical disorder can be considered, from the endocrine point of view, as a variant of the Klinefelter's syndrome.

  10. Constraint of Baryon Asymmetry on Grand Unified Theories and X-X Mass Splitting Scenario for Baryon Number Generation.

    NASA Astrophysics Data System (ADS)

    Soni, Sanjeev Kant

    An important constraint on Grand Unified Theories (GUTs) is the correct estimate of Baryon Asymmetry of the Universe (BAU), in the standard scenario and with a conventional energy-temperature behavior. This is proportional to the intrinsic maximal CP-violation at superhigh energies, which as the lore goes barely accounts for the observed baryon -to-entropy ratio. This is further controlled by some global features: a global symmetry, if broken inadequately, can unduely suppress our estimate and the problem is how to overwhelm the suppression. Illustrated variously, this possibility of the group-theoretical constraint is also contrasted with that of a dynamical constraint. We focus our attention on a specific constraint, that arising from the broken group-C invariance (C = Charge-conjugation), note its implications on neutrino mass and examine, in particular, how to overwhelm the resulting suppression by splitting the mass of the decaying scalar X from its charge conjugate X('c) in an SO(10) theory with Witten's mechanism for neutrino mass. This possibility of X-X('c) mass-splitting was envisaged in our previous general study (with Haber and Segre) whose important conclusions are reviewed: some general observations on spontaneously unbroken C-invariance and a solution to the problem of BAU, in spontaneously broken C-invariant theories, by allowing no overlap between the contributions form the free-decays of X-X(' )and X('c) -X('c) pairs through (nu)-N('c) mass splitting >(, )10('10) GeV, or/and, when X X('c), through X-X('c) mass splitting >(, )m (X). Only the following details are now added. As examples of GUTs with uniquely defined C, we give the maximal and the minimal (single-family) unification schemes based on SU(16) and SO(10) respectively. We discuss in detail the X-X('c) mass splitting scenario with(' )X-X(X('c)-X('c)) belonging to the (6, 3, 1)(,+2) ((6, 1, 3)(,-2)) subcomponent of the 120 of SO(10). In addition to explicitizing the mass-splitting, we

  11. Spatiotemporal behavior of climatic characteristics determining evolution of forest ecosystems in Siberia in the second half of XX century

    NASA Astrophysics Data System (ADS)

    Shulgina, Tamara; Bogomolov, Vasily; Genina, Elena; Gordov, Evgeny

    2010-05-01

    It is well known that both global and regional climate changes influence biological processes occurring in different ecosystems. In particular, they determine forest productivity that plays important role in global carbon balance forming. The paper presents investigation results for climate indices dynamics that determine evolution of forest ecosystems in Siberia in the second half of XX century. The ECMWF data (spatial resolution of 0.5°×0.5°) and observations of the weather stations in Siberia over the period from 1974 to 2000 were taken as initial data. The paper presents calculation results for fields of the following climatic characteristics: duration of growing season and its mean temperature, sum of degree day temperature, precipitation amount and Selyaninov hydrothermal coefficient. Calculation results have shown an increase of growing season duration by 4-6 days in Siberia for all period under study (32 years). Mean air temperature dynamics in growing season has weak positive trend and inhomogeneous structure over all Siberian territory. Thus, maximum increase of mean temperature for growing season is observed in south taiga and is equal to 0.9° C per 32 years. Analysis of precipitation amount dynamics shows inhomogeneity in its change. Significant increase of precipitation amount is observed in temperate forests and steppe. As a results of increase of temperature and precipitation amount, Selyaninov hydrothermal coefficient significantly increases in the south of Siberia that suggests increase of water content in soil on the territory under study. However, to study forest ecosystem response to climate changes, we need climatic characteristics fields with higher spatial resolution. To do this, we used a WRF mesoscale model and calculated meteorological fields with spatial resolution of 10 km. These fields take into account influence of surface layer on climate forming and allow us to analyze in detail local response of forest ecosystems to regional

  12. Homozygosity for a Robertsonian Translocation (13q;14q) in a Phenotypically Normal 44, XX Female with a History of Recurrent Abortion and a Normal Pregnancy Outcome

    PubMed Central

    Miryounesi, Mohammad; Diantpour, Mehdi; Motevaseli, Elahe; Ghafouri-Fard, Soudeh

    2016-01-01

    Background: Robertsonian translocations are structural chromosomal abnormalities caused by fusion of two acrocentric chromosomes. In carriers of such translocations, different modes of segregations would result in the formation of either balanced (alternate segregation mode) or unbalanced (adjacent 1, adjacent 2, and 3:1 segregation modes) gametes. In addition, there is an increased risk for imprinting disorders in their offspring. Although it has been estimated that 1/1000 healthy persons carry a Robertsonian translocation, homozygosity for this type of structural chromosomal abnormality has been reported rarely. Most of reported cases are phenotypically normal but experience adverse pregnancy outcomes. Case Presentation: In this paper, a report was made on a normal female with a history of 4 consecutive first trimester fetal losses and a normal son referred to Center for Comprehensive Genetics Services, Tehran, Iran, in summer 2015. Cytogenetic analyses of proband and her infant showed 44, XX, der(13;14) (q10;q10)x2 and 45, XY, der(13;14)(q10;q10), respectively. Parents of proband have been shown to have 45, XY, der(13q;14q) and 45, XX, der(13q;14q) karyotypes, respectively. Conclusion: The present report was in agreement with the few reports of homozygosity for Robertsonian translocation which demonstrated normal phenotypes for such persons and possibility of giving birth to phenotypically normal heterozygote carriers of Robertsonian translocations. PMID:27478773

  13. Comparing sex steroid levels during the annual cycles of rainbow trout (Oncorhynchus mykiss) diploid female (XX) and triploid female (XXX) genotypic sex.

    PubMed

    Espinosa, E; Josa, A; Gil, L; Malo, C; Mitjana, O

    2013-02-01

    In this study, the annual cycle of the gonadal steroids testosterone (T), 11-ketotestosterone (11-KT), 17β-estradiol (E2) and 17α, 20β-dihydroxy-4-pregnen-3-one (DHP) was determined using radioimmunoassay and then compared for two populations of rainbow trout, XX diploid females (n = 40) and XXX triploid females (n = 15). In females, E2 and DHP levels were found to be significantly related to body weight (r = 0.22513; p < 0.0001 and r = 0.15831; p > 0.001, respectively). In this group, E2 concentrations peaked in November (25.05 ng/ml), while maximum DHP levels, only measurable from October to April, were attained in February (64.14 ng/ml). No significant differences in hormone ranges related to egg output ability were observed. Finally, sex steroid concentrations were low in the triploid female XXX fish compared to the female XX population. Nevertheless, maximum T (33.85 ng/ml) and 11-KT (32.35 ng/ml) levels were recorded in January, for XXX. The levels for these two hormones are relatively high and are also significantly associated (r = 0.8430; p < 0.0001). Diploid females showed significantly higher levels of E2 than triploids over the 12-month study period. The female triploid fish produced the lowest steroid hormone levels, such that these would be the most suitable for human consumption.

  14. A trio of horseshoes: past, present and future dynamical evolution of Earth co-orbital asteroids 2015 XX169, 2015 YA and 2015 YQ1

    NASA Astrophysics Data System (ADS)

    de la Fuente Marcos, C.; de la Fuente Marcos, R.

    2016-04-01

    It is widely accepted that a quasi-steady-state flux of minor bodies moving in and out of the co-orbital state with the Earth may exist. Some of these objects are very good candidates for future in situ study due to their favourable dynamical properties. In this paper, we show that the recently discovered near-Earth asteroids 2015 XX_{169}, 2015 YA and 2015 YQ1 are small transient Earth co-orbitals. These new findings increase the tally of known Earth co-orbitals to 17. The three of them currently exhibit asymmetric horseshoe behaviour subjected to a Kozai resonance and their short-term orbital evolution is rather unstable. Both 2015 YA and 2015 YQ1 may leave Earth's co-orbital zone in the near future as they experience close encounters with Venus, the Earth-Moon system and Mars. Asteroid 2015 XX_{169} may have remained in the vicinity of, or trapped inside, the 1:1 mean motion resonance with our planet for many thousands of years and may continue in that region for a significant amount of time into the future.

  15. Electronic, magnetic and thermal properties of Co2CrxFe1-xX (X=Al, Si) Heusler alloys: First-principles calculations

    NASA Astrophysics Data System (ADS)

    Guezlane, M.; Baaziz, H.; El Haj Hassan, F.; Charifi, Z.; Djaballah, Y.

    2016-09-01

    Density functional theory (DFT) based on the full-potential linearized augmented plane wave (FP-LAPW) method is used to investigate the structural, electronic, magnetic and thermal properties of Co2CrxFe1-xX (X=Al, Si) full Heusler alloys, with L21 structure. The structural properties and spin magnetic moments are investigated by the generalized gradient approximations (GGA) minimizing the total energy. For band structure calculations, GGA, the Engel-Vosko generalized gradient approximation (EVGGA) and modified Becke-Johnson (mBJ) schemes are used. Results of density of states (DOS) and band structures show that these alloys are half-metallic ferromagnets (HMFS). A regular-solution model has been used to investigate the thermodynamic stability of the compounds Co2CrxFe1-xX that indicates a phase miscibility gap. The thermal effects using the quasi-harmonic Debye model are investigated within the lattice vibrations. The temperature and pressure effects on the heat capacities, Debye temperatures and entropy are determined from the non-equilibrium Gibbs functions.

  16. A Euploid Line of Human Embryonic Stem Cells Derived from a 43,XX,dup(9q),+12,-14,-15,-18,-21 Embryo

    PubMed Central

    Fonseca, Simone Aparecida Siqueira; Costas, Roberta Montero; Morato-Marques, Mariana; Costa, Silvia; Alegretti, Jose Roberto; Rosenberg, Carla; da Motta, Eduardo Leme Alves; Serafini, Paulo C.; Pereira, Lygia V.

    2015-01-01

    Aneuploid embryos diagnosed by FISH-based preimplantation genetic screening (PGS) have been shown to yield euploid lines of human embryonic stem cells (hESCs) with a relatively high frequency. Given that the diagnostic procedure is usually based on the analysis of 1–2 blastomeres of 5 to 10-cell cleavage-stage embryos, mosaicism has been a likely explanation for the phenomena. However, FISH-based PGS can have a significant rate of misdiagnosis, and therefore some of those lines may have been derived from euploid embryos misdiagnosed as aneuploid. More recently, coupling of trophectoderm (TE) biopsy at the blastocyst stage and array-CGH lead to a more informative form of PGS. Here we describe the establishment of a new line of hESCs from an embryo with a 43,XX,dup(9q),+12,-14,-15,-18,-21 chromosomal content based on array-CGH of TE biopsy. We show that, despite the complex chromosomal abnormality, the corresponding hESC line BR-6 is euploid (46,XX). Single nucleotide polymorphism analysis showed that the embryo´s missing chromosomes were not duplicated in BR-6, suggesting the existence of extensive mosaicism in the TE lineage. PMID:26540511

  17. Chromosome landmarks and autosome-sex chromosome translocations in Rumex hastatulus, a plant with XX/XY1Y2 sex chromosome system.

    PubMed

    Grabowska-Joachimiak, Aleksandra; Kula, Adam; Książczyk, Tomasz; Chojnicka, Joanna; Sliwinska, Elwira; Joachimiak, Andrzej J

    2015-06-01

    Rumex hastatulus is the North American endemic dioecious plant with heteromorphic sex chromosomes. It is differentiated into two chromosomal races: Texas (T) race characterised by a simple XX/XY sex chromosome system and North Carolina (NC) race with a polymorphic XX/XY1Y2 sex chromosome system. The gross karyotype morphology in NC race resembles the derived type, but chromosomal changes that occurred during its evolution are poorly understood. Our C-banding/DAPI and fluorescence in situ hybridization (FISH) experiments demonstrated that Y chromosomes of both races are enriched in DAPI-positive sequences and that the emergence of polymorphic sex chromosome system was accompanied by the break of ancestral Y chromosome and switch in the localization of 5S rDNA, from autosomes to sex chromosomes (X and Y2). Two contrasting domains were detected within North Carolina Y chromosomes: the older, highly heterochromatinised, inherited from the original Y chromosome and the younger, euchromatic, representing translocated autosomal material. The flow-cytometric DNA estimation showed ∼3.5 % genome downsizing in the North Carolina race. Our results are in contradiction to earlier reports on the lack of heterochromatin within Y chromosomes of this species and enable unambiguous identification of autosomes involved in the autosome-heterosome translocation, providing useful chromosome landmarks for further studies on the karyotype and sex chromosome differentiation in this species.

  18. Spot evolution on the red giant star XX Triangulum. A starspot-decay analysis based on time-series Doppler imaging

    NASA Astrophysics Data System (ADS)

    Künstler, A.; Carroll, T. A.; Strassmeier, K. G.

    2015-06-01

    Context. Solar spots appear to decay linearly proportional to their size. The decay rate of solar spots is directly related to magnetic diffusivity, which itself is a key quantity for the length of a magnetic-activity cycle. Is a linear spot decay also seen on other stars, and is this in agreement with the large range of solar and stellar activity cycle lengths? Aims: We investigate the evolution of starspots on the rapidly-rotating (Prot≈24 d) K0 giant XX Tri, using consecutive time-series Doppler images. Our aim is to obtain a well-sampled movie of the stellar surface over many years, and thereby detect and quantify a starspot decay law for further comparison with the Sun. Methods: We obtained continuous high-resolution and phase-resolved spectroscopy with the 1.2-m robotic STELLA telescope on Tenerife over six years, and these observations are ongoing. For each observing season, we obtained between 5 to 7 independent Doppler images, one per stellar rotation, making up a total of 36 maps. All images were reconstructed with our line-profile inversion code iMap. A wavelet analysis was implemented for denoising the line profiles. To quantify starspot area decay and growth, we match the observed images with simplified spot models based on a Monte Carlo approach. Results: It is shown that the surface of XX Tri is covered with large high-latitude and even polar spots and with occasional small equatorial spots. Just over the course of six years, we see a systematically changing spot distribution with various timescales and morphology, such as spot fragmentation and spot merging as well as spot decay and formation. An average linear decay of D = -0.022 ± 0.002 SH/day is inferred. We found evidence of an active longitude in phase toward the (unseen) companion star. Furthermore, we detect a weak solar-like differential rotation with a surface shear of α = 0.016 ± 0.003. From the decay rate, we determine a turbulent diffusivity of ηT = (6.3 ± 0.5) × 1014 cm2/s and

  19. Familial ring (18) mosaicism in a 23-year-old young adult with 46,XY,r(18) (::p11→q21::)/46,XY karyotype, intellectual disability, motor retardation and single maxillary incisor and in his phenotypically normal mother, karyotype 47,XX,+r(18)(::p11→q21::)/46,XX.

    PubMed

    Balci, Sevim; Tümer, Celal; Karaca, Ciğdem; Bartsch, Oliver

    2011-05-01

    We report on a 23-year-old man with craniofacial findings of the holoprosencephaly spectrum disorder (microcephaly, hypotelorism, depressed nasal bridge, single median maxillary central incisor), fusion of C2-C3 vertebrae, intellectual disability, and severe sleep apnea. Chromosome analysis of blood lymphocytes showed 75% ring (18) cells and 25% normal cells, karyotype mos 46,XY,r(18)(::p11→q21::)[75]/46,XY[25]. His mother was phenotypically normal except for a double ureter and bifid renal pelvis as in his son. She had a supernumerary ring (18) in 10% of blood lymphocytes, karyotype mos 47,XX,+r(18)(::p11→q21::)[10]/46,XX[90]. Familial ring (18) is a rare cytogenetic abnormality. This is the first report of a mother with a supernumerary ring (18) and a son with ring (18) mosaicism. Interestingly, the son showed a true mosaicism (mixoploidy) of ring (18) and normal cells. The mother's 46,XX cells could be easily explained by mitotic instability and ring loss during cell division. However, the coexistence of ring (18) and normal cells in the son is unusual. Possibly, during early postzygotic divisions of a 47,XY,+r(18) zygote, two (possibly subsequent) genetic events could have occurred, one when one normal chromosome 18 was lost (resulting in a cell line with ring 18), and one when the ring 18 was lost (resulting in a cell line without ring, "escape to normal"). Alternatively, the zygote of the son could have been 46,XY,r(18), and postzygotic loss of the ring 18 could have resulted in monosomy 18 cells followed by duplication of chromosome 18 in these cells (a rare mechanism for cell survival previously described as "compensatory" isodisomy).

  20. A rare case of mosaic 45,X/47,XX,+13 in 28-year-old women with secondary amenorrhoea: A case report and literature review

    PubMed Central

    Kumar, Mohit; Lal, Vandana; Chapadgaonkar, Shilpa; Bhattacharya, Saurabh Kumar

    2014-01-01

    In the present paper we report an extremely rare case of mosaicism of 45,X/47,XX,+13 in a 28-year-old women. The patient was referred for cytogenetic evaluation for secondary amenorrhoea. The patient was found to have some mild characteristic features of Turner syndrome such as wide carrying angle and short stature. Ultrasound examination revealed the presence of a small sized uterus and bilateral streak ovaries. G-banded chromosome analysis revealed a mosaic female karyotype involving two different cell lines. One cell line (72% of analysed metaphases) presented monosomy of X while the remaining 28% of cells showed trisomy of chromosome 13. Fluorescence in situ hybridization (FISH) with locus specific probe for trisomy 13 and CEP X for monosomy X substantiated the results obtained from karyotyping. PMID:26925371

  1. Gonadal dysgenesis and the Mayer-Rokitansky-Kuster-Hauser Syndrome in a girl with a 46, XX karyotype: A case report and review of literature

    PubMed Central

    Kebaili, Sahbi; Chaabane, Kais; Mnif, Mouna Feki; Kamoun, Mahdi; Kacem, Faten Hadj; Guesmi, Nouha; Gassara, Hichem; Dammak, Abdallah; Louati, Doulira; Amouri, Habib; Guermazi, Mohamed

    2013-01-01

    Mayer-Rokitansky-Kuster-Hauser (MRKH) is a characteristic syndrome in which the Mullerian structures are absent or rudimentary. It is also associated with anomalies of the genitourinary and skeletal systems. Its association with gonadal dysgenesis is extremely rare and appears to be fortuitous, independent of chromosomal anomalies. We report such a case in a 21-year-old girl who presented primary amenorrhea and impuberism. The endocrine study revealed hypergonadotrophic hypogonadism. The karyotype was normal, 46, XX. No chromosome Y was detected at the fluorescence in situ hybridization (FISH) analysis. Internal genitalia could not be identified on the pelvic ultrasound and pelvic magnetic resonance imaging. Laparoscopy disclosed concomitant ovarian dysgenesis and MRKH syndrome. There were no other associated malformations. Hormonal substitution therapy with oral conjugated estrogens was begun. The patient has been under regular follow-up for the last two years and is doing well. PMID:23869310

  2. Gonadal dysgenesis and the Mayer-Rokitansky-Kuster-Hauser Syndrome in a girl with a 46, XX karyotype: A case report and review of literature.

    PubMed

    Kebaili, Sahbi; Chaabane, Kais; Mnif, Mouna Feki; Kamoun, Mahdi; Kacem, Faten Hadj; Guesmi, Nouha; Gassara, Hichem; Dammak, Abdallah; Louati, Doulira; Amouri, Habib; Guermazi, Mohamed

    2013-05-01

    Mayer-Rokitansky-Kuster-Hauser (MRKH) is a characteristic syndrome in which the Mullerian structures are absent or rudimentary. It is also associated with anomalies of the genitourinary and skeletal systems. Its association with gonadal dysgenesis is extremely rare and appears to be fortuitous, independent of chromosomal anomalies. We report such a case in a 21-year-old girl who presented primary amenorrhea and impuberism. The endocrine study revealed hypergonadotrophic hypogonadism. The karyotype was normal, 46, XX. No chromosome Y was detected at the fluorescence in situ hybridization (FISH) analysis. Internal genitalia could not be identified on the pelvic ultrasound and pelvic magnetic resonance imaging. Laparoscopy disclosed concomitant ovarian dysgenesis and MRKH syndrome. There were no other associated malformations. Hormonal substitution therapy with oral conjugated estrogens was begun. The patient has been under regular follow-up for the last two years and is doing well.

  3. A rare case of mosaic 45,X/47,XX,+13 in 28-year-old women with secondary amenorrhoea: A case report and literature review.

    PubMed

    Kumar, Mohit; Lal, Vandana; Chapadgaonkar, Shilpa; Bhattacharya, Saurabh Kumar

    2015-02-01

    In the present paper we report an extremely rare case of mosaicism of 45,X/47,XX,+13 in a 28-year-old women. The patient was referred for cytogenetic evaluation for secondary amenorrhoea. The patient was found to have some mild characteristic features of Turner syndrome such as wide carrying angle and short stature. Ultrasound examination revealed the presence of a small sized uterus and bilateral streak ovaries. G-banded chromosome analysis revealed a mosaic female karyotype involving two different cell lines. One cell line (72% of analysed metaphases) presented monosomy of X while the remaining 28% of cells showed trisomy of chromosome 13. Fluorescence in situ hybridization (FISH) with locus specific probe for trisomy 13 and CEP X for monosomy X substantiated the results obtained from karyotyping.

  4. A search for parent molecules at millimetre wavelengths in Comets Austin 1990 V and Levy 1990 XX - Upper limits for undetected species

    NASA Astrophysics Data System (ADS)

    Crovisier, J.; Bockelee-Morvan, D.; Colom, P.; Despois, D.; Paubert, G.

    1993-03-01

    The microwave spectra of Comets Austin 1990 V and Levy 1990 XX were observed with the IRAM 30-m radio telescope. As we have reported previously, the HCN, H2S, H2CO, and CH3OH molecules were detected. In addition, the lines of several other molecules of cometary interest were searched for without success, either during dedicated searches or serendipitously: H2O2, CH3CCH, HCOOH, C2H5OH, CH3OCH3, CH3COOH, HC3HO, HC3N, and many others. We report these searches in detail and evaluate the corresponding limits on the production rates. For several molecules, this limit is of the order of 0.001 relative to water, or less. The consequences for the nature of comets are discussed.

  5. [The scientific revolution in medicine of the last quarter of XIX-first half of XX centuries. Report I. The causes and mechanisms of scientific revolution].

    PubMed

    Stochik, A M; Zatravkin, S N

    2015-01-01

    The article describes the system of conceptions about subject of investigation in medicine and methods of research activities of physicians well-established by early 70s of XIX century. It is postulated that in the middle of 1870s in medicine occurred an objective need of entirely different from before vision of investigated reality, development and implementation of fundamentally new methodological approaches to its studying that by-turn initiated global scientific revolution in medicine of the last quarter of XIX-first half of XX centuries. It is substantiated that need of new vision of investigated reality became first of all a consequence of profound intra-disciplinary crisis related to awareness of fallibility of existed ideas of human organism and its vital activity. The second cause is two "paradigm inoculations" from biology which resulted in forced acceptance by physicians the extreme incompleteness and fallacy of their previous views concerning environment and essence of its effect on human organism.

  6. [Drugs in artistic works of Stanislaw Ignacy Witkiewicz (1885-1939) on the Background of polish modernism at the turn of XIX and XX century].

    PubMed

    Płonka-Syroka, B

    1997-01-01

    At the turn of XIX and XX century in the Polish artistic circles it became widespread a modernist moral model, created among other by Baudelair's, Mallarme's Rimbaud's and Verlain's works. One of its elements was striving for getting into different status of conscience with help of narcotics and alcohol. A strong presence of narcotics in life of the Polish artistic circles at a time of mocernism has been a subject to analysis carried out by Tadeusz Boy-Zeleénski in his work "Cyganeria krakowska" [Crakow Bohemians]. He has shown their role of easing emotional tensions connected with striving for fame and with a competition. Underestimation, misery and social alienation of some artists have been inducing them to search in narcotics the way to artificial reality. In some Polish artistic circles the narcotics have become a stimulant of cult character (see Antoni Lange "Ballady pijackie", Stanisław Przybyszewski "Synowie ziemi", "Moi współcześni", Henryk Sienkiewicz "Bez dogmatu"). Stanisław Ignacy Witkiewicz (1885-1939), Polish painter and dramatist, creating in the first half of XX century, has continued a tradition of modernist customs, taken over by him from the artistic circle he was brought up. He used narcotics as direct creative stimulus, inspiring creation of his paintings, including a superb series of portraits. In paintings made under influence of the drugs, Witkiewicz was placing the symbols of stimulants taken earlier. He has specially appreciated cocaine, though he has been using also opium, morphine, hashish and mixes of various psychotropic agents. Paintings of Witkacy are characterised by original colouring of a very strong artistic expression. ...

  7. Paracentric inversion of chromosome 7 (46,XX,inv(7)(q21.2q22)) in a newborn with hypoplastic left heart syndrome

    SciTech Connect

    Kuforjii, T.A.; Pillers, D.M.; Silberbach, M.

    1994-09-01

    Hypoplastic left heart syndrome (HLHS) is a severe congenital heart disease that is uniformly fatal without surgical intervention. Fetal echocardiography allows prenatal diagnosis, but this condition may not become apparent until after the mid-second trimester. We report a term baby with severe HLHS who had an 18 week fetal ultrasound that reportedly demonstrated a normal heart. There was no family history of congenital heart disease. She was phenotypically female with no dysmorphic features. Physical examination was otherwise normal. She expired at 48 hours of age. The autopsy was noncontributory. The karyotype was 46,XX, but there was an apparently balanced paracentric inversion of the long arm of chromosome 7 (46,XX,inv(7)(q21.2q22)). The mother`s chromosome study was normal without any inversion, and the father was not available for study. Hypoplastic left heart syndrome has been associated with extracardiac anomalies and chromosomal abnormalities including 45,XO,11q-, and trisomy 18. It has also been reported in 5 members spanning 3 generations of a family with a spectrum of left heart defects suggesting an autosomal dominant pattern with high penetrance. First-degree relatives of infants with HLHS have a thirteen percent incidence of related cardiovascular malformations, a frequency higher than predicted by a multifactorial model of inheritance, suggesting that at least a portion of HLHS have a genetic basis. Karyotype analysis, including high resolution banding, may help define the etiology of this condition. Chromosome 7 has not been implicated in HLHS. This case emphasizes the need for genetic analysis, including a pedigree, of affected families. It also underscores the importance of screening by karyotype analysis to determine whether defects of the long arm of chromosome 7 are important in the pathogenesis of hypoplastic left heart syndrome.

  8. Equine disorders of sexual development in 17 mares including XX, SRY-negative, XY, SRY-negative and XY, SRY-positive genotypes.

    PubMed

    Villagómez, D A F; Lear, T L; Chenier, T; Lee, S; McGee, R B; Cahill, J; Foster, R A; Reyes, E; St John, E; King, W A

    2011-01-01

    We described the clinical, cytogenetic and molecular findings of 17 clinical equine cases presented for abnormal sexual development and infertility. Six horses with an enlarged clitoris had an XX, SRY-negative genotype, which displayed male-like behavior (adult individuals). Bilateral ovotestes were noted in 2 of those cases, while another case showed increased levels of circulating testosterone. Six horses with a female phenotype, including normal external genitalia, had an XY, SRY-negative genotype. These individuals had small gonads and an underdeveloped internal reproductive tract. Four horses with normal appearing external genitalia had an XY, SRY-positive genotype, 3 of them had hypoplastic testes and male-like behavior. In addition, one young filly with enlarged clitoris and hypoplastic testes had the same genotype but did not show male-like behavior due to her age. Three of these horses were related with 2 being siblings. These findings demonstrate the diversity of disorders of sexual development seen in the horse. Furthermore, they emphasize the need for further research to identify genes involved in abnormal sex determination and differentiation in the horse.

  9. New Intermetallic Ternary Phosphide Chalcogenide AP2-xXx (A = Zr, Hf; X = S, Se) Superconductors with PbFCl-Type Crystal Structure

    NASA Astrophysics Data System (ADS)

    Kitô, Hijiri; Yanagi, Yousuke; Ishida, Shigeyuki; Oka, Kunihiko; Gotoh, Yoshito; Fujihisa, Hiroshi; Yoshida, Yoshiyuki; Iyo, Akira; Eisaki, Hiroshi

    2014-07-01

    We have synthesized a series of intermetallic ternary phosphide chalcogenide superconductors, AP2-xXx (A = Zr, Hf; X = S, Se), using the high-pressure synthesis technique. These materials have a PbFCl-type crystal structure (space group P4/nmm) when x is greater than 0.3. The superconducting transition temperature Tc changes systematically with x, yielding dome-like phase diagrams. The maximum Tc is achieved at approximately x = 0.7, at which point the Tc is 6.3 K for ZrP2-xSex (x = 0.75), 5.5 K for HfP2-xSex (x = 0.7), 5.0 K for ZrP2-xSx (x = 0.675), and 4.6 K for Hfp2-xSx (x = 0.5). They are typical type-II superconductors and the upper and lower critical fields are estimated to be 2.92 T at 0 K and 0.021 T at 2 K for ZrP2-xSex (x = 0.75), respectively.

  10. A Non-Reciprocal Autosomal Translocation 64,XX, t(4;10)(q21;p15) in an Arabian Mare with Repeated Early Embryonic Loss.

    PubMed

    Ghosh, S; Das, P J; Avila, F; Thwaits, B K; Chowdhary, B P; Raudsepp, T

    2016-02-01

    Balanced autosomal translocations are a known cause for repeated early embryonic loss (REEL) in horses. In most cases, carriers of such translocations are phenotypically normal, but the chromosomal aberration negatively affects gametogenesis giving rise to both genetically balanced and unbalanced gametes. The latter, if involved in fertilization, result in REEL, whereas gametes with the balanced form of translocation will pass the defect into next generation. Therefore, in order to reduce the incidence of REEL, identification of translocation carriers is critical. Here, we report about a phenotypically normal 3-year-old Arabian mare that had repeated resorption of conceptuses prior to day 45 of gestation and was diagnosed with REEL. Conventional and molecular cytogenetic analyses revealed that the mare had normal chromosome number 64,XX but carried a non-mosaic and non-reciprocal autosomal translocation t(4;10)(q21;p15). This is a novel translocation described in horses with REEL and the first such report in Arabians. Previous cases of REEL due to autosomal translocations have exclusively involved Thoroughbreds. The findings underscore the importance of routine cytogenetic screening of breeding animals.

  11. Extended calculations of level and transition properties in the nitrogen isoelectronic sequence: Cr XVIII, Fe XX, Ni XXII, and Zn XXIV

    NASA Astrophysics Data System (ADS)

    Radžiūtė, L.; Ekman, J.; Jönsson, P.; Gaigalas, G.

    2015-10-01

    Extensive multiconfiguration Dirac-Hartree-Fock (MCDHF) calculations and relativistic configuration interaction (RCI) calculations are performed for 272 states of the 2s22p3, 2s2p4, 2p5, 2s22p23l, 2s2p33l, and 2p43l (l = 0,1,2) configurations in the nitrogen-like ions Cr XVIII, Fe XX, Ni XXII, and Zn XXIV. Valence, core-valence, and core-core electron correlation effects are accounted for through large configuration state function expansions. Calculated energy levels are compared with data from other calculations and with experimental data from the NIST database. Landé gJ-factors; hyperfine structures; isotope shifts; and radiative electric dipole (E1), electric quadrupole (E2), and magnetic dipole (M1) transition rates are given for all ions. The accuracy of the calculated energy levels is high enough to facilitate identification of observed spectral lines involving the 2l43l' configurations, for which experimental data are largely missing. Tables 5-21 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/582/A61

  12. Karyotypic analysis and FISH mapping of microsatellite motifs reveal highly differentiated XX/XY sex chromosomes in the pink-tailed worm-lizard (Aprasia parapulchella, Pygopodidae, Squamata)

    PubMed Central

    2013-01-01

    Background The infraorder Gekkota is intriguing because it contains multiple chromosomal and environmental sex determination systems that vary even among closely related taxa. Here, we compare male and females karyotypes of the pink-tailed worm-lizard (Aprasia parapulchella), a small legless lizard belonging to the endemic Australian family Pygopodidae. Results We applied comparative genomic hybridization to reveal an XX/XY sex chromosome system in which the Y chromosome is highly differentiated from the X in both gross morphology and DNA sequence. In addition, FISH mapping has revealed that two microsatellite repeat motifs, (AGAT)n and (AC)n, have been amplified multiple times on the Y chromosome. Conclusion XY karyotypes are found in other pygopodids (Delma inornata and Lialis burtonis), suggesting that the common ancestor of Pygopodidae also had XY sex chromosomes. However, the morphology and size of the Y chromosomes are different among the three species, suggesting that the processes underlying the evolution of sex chromosomes in the Pygopodidae involved chromosome rearrangements and accumulation and amplification of repeats. PMID:24344753

  13. An XX/XY heteromorphic sex chromosome system in the Australian chelid turtle Emydura macquarii: a new piece in the puzzle of sex chromosome evolution in turtles.

    PubMed

    Martinez, Pedro Alonzo; Ezaz, Tariq; Valenzuela, Nicole; Georges, Arthur; Marshall Graves, Jennifer A

    2008-01-01

    Chromosomal sex determination is the prevalent system found in animals but is rare among turtles. In fact, heteromorphic sex chromosomes are known in only seven of the turtles possessing genotypic sex determination (GSD), two of which correspond to cryptic sex microchromosomes detectable only with high-resolution cytogenetic techniques. Sex chromosomes were undetected in previous studies of Emydura macquarii, a GSD side-necked turtle. Using comparative genomic hybridization (CGH) and GTG-banding, a heteromorphic XX/XY sex chromosome system was detected in E. macquarii. The Y chromosome appears submetacentric and somewhat larger than the metacentric X, the first such report for turtles. CGH revealed a male-specific chromosomal region, which appeared heteromorphic using GTG-banding, and was restricted to the telomeric region of the p arm. Based on our observations and the current phylogeny of chelid turtles, we hypothesize that the sex chromosomes of E. macquarii might be the result of a translocation of an ancestral Y microchromosome as found in a turtle belonging to a sister clade, Chelodina longicollis, onto the tip of an autosome. However, in the absence of data from an outgroup, the opposite (fission of a large XY into an autosome and a micro-XY) is theoretically equally likely. Alternatively, the sex chromosome systems of E. macquarii and C. longicollis may have evolved independently. We discuss the potential causes and consequences of such putative chromosome rearrangements in the evolution of sex chromosomes and sex-determining systems of turtles in general.

  14. AB INITIO STUDY OF STRUCTURAL, ELECTRONIC AND OPTICAL PROPERTIES OF MgxCd1-xX (X = S, Se, Te) ALLOYS

    NASA Astrophysics Data System (ADS)

    Noor, N. A.; Shaukat, A.

    2012-12-01

    This study describes structural, electronic and optical properties of MgxCd1-xX (X = S, Se, Te) alloys in the complete range 0≤x ≤1 of composition x in the zinc-blende (ZB) phase with the help of full-potential linearized augmented plane wave plus local orbitals (FP-LAPW+lo) method within density functional theory (DFT). In order to calculate total energy, generalized gradient approximation (Wu-Cohen GGA) has been applied, which is based on optimization energy. For electronic structure calculations, the corresponding potential is being optimized by Engel-Vosko GGA formalism. Our calculations reveal the nonlinear variation of lattice constant and bulk modulus with different concentration for the end binary and their ternary alloys, which slightly deviates from Vegard's law. The calculated band structures show a direct band gap for all three alloys with increasing order in the complete range of the compositional parameter x. In addition, we have discussed the disorder parameter (gap bowing) and concluded that the total band gap bowing is substantially influenced by the chemical (electronegativity) contribution. The calculated density of states (DOS) of these alloys is discussed in terms of contribution from various s-, p- and d-states of the constituent atoms and charge density distributions plots are analyzed. Optical properties have been presented in the form of the complex dielectric function ɛ(ω), refractive index n(ω) and extinction coefficient k(ω) as function of the incident photon energy, and the results have been compared with existing experimental data and other theoretical calculations.

  15. Projective line over the finite quotient ring GF(2)[x]/ 3 ™ x> and quantum entanglement: The Mermin ``magic'' square/pentagram

    NASA Astrophysics Data System (ADS)

    Saniga, M.; Planat, M.; Minarovjech, M.

    2007-05-01

    In 1993, Mermin gave surprisingly simple proofs of the Bell-Kochen-Specker (BKS) theorem in Hilbert spaces of dimensions four and eight respectively using what has since been called the Mermin-Peres “magic” square and the Mermin pentagram. The former is a 3×3 array of nine observables commuting pairwise in each row and column and arranged such that their product properties contradict those of the assigned eigenvalues. The latter is a set of ten observables arranged in five groups of four lying along five edges of the pentagram and characterized by a similar contradiction. We establish a one-to-one correspondence between the operators of the Mermin-Peres square and the points of the projective line over the product ring GF(2) ⊗ GF(2). Under this map, the concept mutually commuting transforms into mutually distant, and the distinguishing character of the third column’s observables has its counterpart in the distinguished properties of the coordinates of the corresponding points, whose entries are either both zero divisors or both units. The ten operators of the Mermin pentagram correspond to a specific subset of points of the line over GF(2)[x]/3 ™ x>. But the situation in this case is more intricate because there are two different configurations that seem to serve our purpose equally well. The first one comprises the three distinguished points of the (sub)line over GF(2), their three “Jacobson” counterparts, and the four points whose both coordinates are zero divisors. The other con.guration features the neighborhood of the point (1, 0) (or, equivalently, that of (0, 1)). We also mention some other ring lines that might be relevant to BKS proofs in higher dimensions.

  16. Costs of landslides and floods in XX Century in a Calabrian town starting from the data stored in the Historical Archive of IRPI (Cosenza)

    NASA Astrophysics Data System (ADS)

    Giampa', Vincenzo; Pasqua, A. Aurora; Petrucci, Olga

    2015-04-01

    The paper firstly presents the historical archive of Cosenza IRPI Section and the historical database that has been built basing on the data contained in it. Then, an application of these data to Catanzaro, the town that is the administrative center of Calabria region (Southern Italy), is presented. The gathering of historical data on past floods and landslides in Cosenza IRPI Section has been started since 1996, and it is still in progress. In 2005, some donations coming from regional and municipal Public Works offices greatly increased the documental corpus, and required a more incisive classification and management that led us to organize the documents in a real historical archive. Documents were sorted according to municipalities they concerned. In this way, for each of the 409 municipalities of Calabria a set of documents, maps and images was available. Collected documents mainly concern damage caused by the occurrence, since XIX century, of phenomena as floods, flash floods and landslides triggered by extreme meteorological events, or even damage caused by strong earthquakes. At the beginning of 2014, the central office of IRPI (Perugia) funded a project aiming to the digitalization of the archive and the subsequent publication of it on a web-platform. In this paper, the procedure adopted to build the archive and implement the database is described. Then, the elaboration of the historical series of data on Catanzaro town, which has been frequently damaged by rainfall-induced landslides and floods, is also presented. Basing on the documents coming from the archive of Ministry Public Works and stored in our Historical Archive, an assessment of costs related to damage that during XX century affected the houses of this town has been performed. The research pointed out the types of most damaging phenomena, the municipal sectors most frequently damaged, and the evolution of damaged areas throughout the years according to the increasing urbanization.

  17. Time-resolved photometry of the nova remnants DM Gem, CP Lac, GI Mon, V400 Per, CT Ser and XX Tau

    NASA Astrophysics Data System (ADS)

    Rodríguez-Gil, P.; Torres, M. A. P.

    2005-02-01

    We present the first results of a photometric survey of poorly studied nova remnants in the Northern Hemisphere. The main results are as follows: DM Gem shows a modulation at 0.123 d (probably linked to the orbit) and rapid variations at ˜ 22 min. A moderate resolution spectrum taken at the time of the photometric observations shows intense He II 4686 and Bowen emission, characteristic of an intermediate polar or a SW Sex star. Variability at 0.127 d and intense flickering (or quasi-periodic oscillations) are the main features of the light curve of CP Lac. A 0.1-mag dip lasting for ˜ 45 min is observed in GI Mon, which could be an eclipse. A clear modulation (probably related to the orbital motion) either at 0.179 d or 0.152 d is observed in the B-band light curve of V400 Per. The results for CT Ser point to an orbital period close to 0.16 d. Intense flickering is also characteristic of this old nova. Finally, XX Tau shows a possible periodic signal near 0.14 d and displays fast variability at ˜ 24 min. Its brightness seems to be modulated at ˜ 5 d. We relate this long periodicity to the motion of an eccentric/tilted accretion disc in the binary. Based in part on observations made with the Jacobus Kapteyn Telescope, which was operated on the island of La Palma by the Isaac Newton Group in the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofísica de Canarias (IAC), and on observations made with the IAC80 telescope, operated on the island of Tenerife by the IAC in the Spanish Observatorio del Teide of the IAC. Observations were also obtained at the FLWO Observatory, a facility of the Smithsonian Institution.

  18. Certification of new Pb iCRM (Candidate ERM-38xx series) via Gravimetric Isotope Mixtures and MC-ICP-MS Measurements

    NASA Astrophysics Data System (ADS)

    Ponzevera, E.; Quetel, C. R.

    2008-12-01

    Lead is known to be a particularly toxic chemical element. Mining and smelting of Pb and its domestic use over the centuries have contaminated the surface of Earth and jeopardized the health of humans, domestic animals and wildlife. Omnipresence of Pb has however an advantage. It can be used as an isotopic tracer of pollution sources and pathways in the environment. Pb isotopic Certified Reference Materials (iCRM) with undisputed characteristics are then required to validate Pb isotope ratio measurements. The materials currently available worldwide were produced in the 1960's by the National Bureau of Standards (now NIST, USA) and are now the object of polemics regarding the accuracy of some of the accompanying certified values. Moreover, new materials with lower relative uncertainty statements are demanded by users. This presentation is centred on the production and the certification at the EC-JRC-Institute for Reference Materials and Measurements of a new series of Pb iCRM (candidate ERM-38xx series). The production included six Pb gravimetric isotope mixtures, a common Pb material dedicated to routine calibration work and a series of four 207Pb slightly enriched natural-like Pb materials for the validation of the δ-scale method below 0.01%. The gravimetric isotope mixtures method, originally supported by mass spectrometry measurements performed on GS-MS or TI-MS instruments, was applied successfully to MC-ICP-MS. The measurements and certification methods we developed were validated in several ways, including a systematic investigation on possible significant sources of uncertainty and comparisons of results obtained by different laboratories on identical samples. Relative uncertainties on isotope ratios obtained for the newly produced Pb iCRM are as low as 0.017%, which is between 2 and 4 times smaller than the uncertainties carried by the NIST-981 material. Going below 0.01% was not possible mainly because of uncompressible uncertainties coming from the

  19. Genomic profile of a Li-Fraumeni-like syndrome patient with a 45,X/46,XX karyotype, presenting neither mutations in TP53 nor clinical stigmata of Turner syndrome.

    PubMed

    Basso, Tatiane R; Villacis, Rolando A R; Canto, Luisa M; Alves, Vinicius M F; Lapa, Rainer M L; Nóbrega, Amanda F; Achatz, Maria I; Rogatto, Silvia R

    2015-06-01

    Li-Fraumeni syndrome (LFS) is a hereditary disorder that predisposes patients to several types of cancer and is associated with TP53 germline mutations. Turner syndrome (TS) is one of the most common aneuploidies in women. Patients with TS have a higher risk of developing cancer, although multiple malignant tumors are extremely rare. Herein, we describe a patient with a 45,X/46,XX karyotype with no classic phenotype of TS. She presented with a clinical diagnosis of Li-Fraumeni-like syndrome (LFL), showing papillary thyroid carcinoma and fibrosarcoma of the left flank, and had no TP53 germline mutations. Genome-wide analysis of copy number variations (CNVs) was assessed in DNA from peripheral blood cells and saliva. A total of 109 rare CNVs in the blood cells, including mosaic loss of the X chromosome (76% of cells), were identified. In saliva, three rare CNVs were detected, all of them were also detected in the blood cells: loss of 8q24.11 (EXT1), gain of 16q24.3 (PRDM7 and GAS8), and the mosaic loss of the X chromosome (50% of cells). Results of conventional G-banding confirmed the 45,X/46,XX karyotype. Surprisingly, the patient presented with an apparently normal phenotype. The PRDM and GAS8 genes are potential candidates to be associated with the risk of developing cancer in this LFL/TS patient.

  20. Asplenia syndrome in a child with a balanced reciprocal translocation of chromosomes 11 and 20 [46,XX,t(11;20)(q13.1;q13.13)

    SciTech Connect

    Freeman, S.B.; May, K.M.; Blackston, R.D.; Muralidharan, K.

    1996-02-02

    We present a 6-year-old girl with a balanced 11;20 translocation [46,XX,t(11;20)(q13.1;q13.13)pat], asplenia, pulmonic stenosis, Hirschsprung disease, minor anomalies, and mental retardation. This case represents the second report of an individual with situs abnormalities and a balanced chromosome rearrangement involving a breakpoint at 11q13. Segregation analysis of markers in the 11q13 region in the proposita and her phenotypically normal carrier sibs did not show a unique combination of maternal and paternal alleles in the patient. We discuss several possible explanations for the simultaneous occurrence of situs abnormalities and a balanced 11;20 translocation. These include (1) chance, (2) a further chromosome rearrangement in the patient, (3) gene disruption and random situs determination, and (4) gene disruption plus transmission of a recessive or imprinted allele from the mother. 30 refs., 1 fig., 2 tabs.

  1. Asplenia syndrome in a child with a reciprocal translocation of chromosomes 11 and 20 [46,XX,t(11;20)(q13.1;q13.13)

    SciTech Connect

    Freeman, S.B.; Muraldharan, K.; Pettay, D.

    1994-09-01

    Failure to establish the left-right embryonic axis results in abnormalities of laterality; situs solitus is replaced by situs inversus totalis or various degrees of heterotaxy involving the heart, great vessels, lungs, liver, spleen, and/or bowel. Laterality syndromes are likely to be genetically heterogeneous although specific human genes have not been identified. Families with dominant, recessive, and X-linked laterality syndromes have been reported as well as individuals with situs abnormalities and chromosome rearrangements. The latter offer the possibility of narrowing the gene search to specific chromosome regions. A recent report described an infant with polysplenia syndrome and a paracentric inversion of chromosome 11 [46,XX,inv(11)(q13q25)pat]. We report the second case of a child with laterality abnormalities and a chromosome rearrangement involving a similar breakpoint on chromosome 11. The proband is a 6 y/o female with mental retardation, dysmorphic features, pulmonic stenosis, asplenia, Hirschsprung disease, and a balanced, reciprocal translocation involving chromosomes 11 and 20 [46,XX,t(11;20)(q13,1;q13.13)pat]. Using DNA probes we have excluded uniparental disomy for chromosomes 11 and 20. If a gene for determination of laterality lies in the 11q13 region, the proband`s abnormalities could be the result of her receiving an allele disrupted by the paternal translocation as well as a mutant allele from her mother. To investigate this possibility, we are studying the segregation of maternal chromosome 11 markers in the proband and her balanced carrier and non-carrier siblings.

  2. Extremely low losses 14xx single mode laser diode leading to 550-mW output power module with 0-75°C case temperature and 10-W consumption

    NASA Astrophysics Data System (ADS)

    Burie, J.-R.; Garabedian, P.; Starck, C.; Pagnod-Rossiaux, P.; Bettiati, M.; Do Nascimento, M.; Reygrobellet, J.-N.; Bertreux, J.-C.; Laruelle, F.

    2012-03-01

    High power 14xx laser pumps are more and more required for eye safe industrial, medical, safety and defense applications as well as for increased telecom network capability (e.g. for 100 Gb Ethernet). However, this need of high power requires to control the overall power consumption in a range in line with systems requirements. In this respect, 3S PHOTONICS has developed a 14xx nm single mode laser diode with record internal losses of 1.5 cm-1 compared to the 2.7 cm-1 reported up to now. These lasers are based on p/nBH technology and use the asymmetric waveguide concept to reduce internal losses. The record loss value, coupled to an internal efficiency higher than 0.8, allows realization lasers of 3 mm length with external efficiency higher than 0.5 W.A-1 at 25°C in AR/HR coating configuration. Modules using direct coupling technology were realized. High coupling efficiency is obtained thanks to the 8° x 14° far field pattern of the diode. Output power of 550 mW at 1.8 A is thus obtained, with or without FBG stabilization, with maximum output power above 700mW. Thanks to the lasers' length, voltage at this current level is below 1.9 V, which gives a reduced thermal load. Thus, the overall modules electrical consumption remains lower than 10 W at case temperatures ranging from 0°C to 75°C. The 3 mm length also guaranties high reliability of these laser diodes.

  3. Non-Ideal p-n junction Diode of Sb{sub x}Se{sub 1-x}(x = 0.4, 0.5, 0.6, 0.7) Thin Films

    SciTech Connect

    Mustafa, Falah I.; Gupta, Shikha; Goyal, N.; Tripathi, S. K.

    2011-12-12

    We have made diodes consisting of the same alloy i.e. Sb{sub x}Se{sub 1-x}(x = 0.4, 0.5, 0.6 and 0.7), but change the concentration of Sb metal from 40% to 70% atomic weight percentage. It is observed from the Hall measurements that the nature of charge carriers have changed from p- to n-type at x = 0.6 for Sb{sub x}Se{sub 1-x}. We have measured I-V characteristics of four p-n junction diodes i.e. p-Sb{sub 2}Se{sub 3}/n-Sb{sub 3}Se{sub 2}, p-Sb{sub 2}Se{sub 3}/n-Sb{sub 7}Se{sub 3}, p-SbSe/n-Sb{sub 3}Se{sub 2}, p-SbSe/n-Sb{sub 7}Se{sub 3}. From the I-V plots we have calculated the parameters as built-in voltage (V{sub bi}), forward resistance (R{sub f}), ideal factor (n), saturation current (I{sub o}), breakdown current (I{sub Bd}) and breakdown voltage (V{sub Bd}).

  4. Fatal Outcome in a Newborn Calf Associated with Partial Trisomy 25q and Partial Monosomy 11q, 60,XX,der(11)t(11;25)(q11;q14∼21).

    PubMed

    Iannuzzi, Alessandra; Genualdo, Viviana; Perucatti, Angela; Pauciullo, Alfredo; Varricchio, Giovanna; Incarnato, Domenico; Matassino, Donato; Iannuzzi, Leopoldo

    2015-01-01

    A newborn calf of the Agerolese cattle breed underwent clinical cytogenetic investigation because of hyperflexion of the forelimbs, red eyes and the inability to stand. Anamnesis revealed that the mother, phenotypically normal, carried a chromosomal aberration. The newborn died after 2 weeks, and no remarkable alterations were found by the veterinarian on postmortem examination. The mother was a carrier of a reciprocal balanced translocation rcp(11;25)(q11,q14∼21) detected after a cytogenetic investigation in 2011; however, the analysis of the newborn revealed a different chromosomal aberration with partial trisomy of chromosome 25 and partial monosomy of chromosome 11. In fact, the results showed both chromosomes 25, one chromosome 11 and only one long derivative chromosome (der11). FISH analysis, performed using BAC clones, confirmed the chromosomes and their regions involved. Finally, both the localization of the breakpoints on band q11 (centromere) of chromosome 11 and band q14-21 of chromosome 25, and the complete loss of the der25 identified the aberration as an unbalanced translocation 60,XX,der(11)t(11;25)(q11;q14∼21). A comparison with human chromosomes was also performed to search for similarities and possible genes involved in order to study their effects, thus extending the knowledge of these aberrations by case reports.

  5. XX International Workshop on Condensed Matter Theories

    DTIC Science & Technology

    1998-01-01

    Rojo5, M.A. Solis6 and A.A. Valladares4 1 Institute de Fisica Teorica -UNESP, 01405 Säo Paulo, BRAZIL and Departamento de Fisica, Universidade...an elegant functional integral approach which in lowest-order gives a Ginzburg- Landau theory. Following Ref. [30] a generalized coherence length (or...representing Landau damping due to the wave particle interactions [16]. For a nonequilibrium plasma with a two peaked distribution function f0(u) (e.g

  6. Draco,Version 6.x.x

    SciTech Connect

    Thompson, Kelly; Budge, Kent; Lowrie, Rob; Rockefeller, Gabriel; Warsa, James; Wollaber, Allan; Chang, Jae; Cleveland, Matthew

    2016-03-03

    Draco is an object-oriented component library geared towards numerically intensive, radiation (particle) transport applications built for parallel computing hardware. It consists of semi-independent packages and a robust build system. The packages in Draco provide a set of components that can be used by multiple clients to build transport codes. The build system can also be extracted for use in clients. Software includes smart pointers, Design-by-Contract assertions, unit test framework, wrapped MPI functions, a file parser, unstructured mesh data structures, a random number generator, root finders and an angular quadrature component.

  7. The Function sin x/x.

    ERIC Educational Resources Information Center

    Gearhart, William B.; Shultz, Harris S.

    1990-01-01

    Presents some examples from geometry: area of a circle; centroid of a sector; Buffon's needle problem; and expression for pi. Describes several roles of the trigonometric function in mathematics and applications, including Fourier analysis, spectral theory, approximation theory, and numerical analysis. (YP)

  8. Planck 2015 results. XX. Constraints on inflation

    NASA Astrophysics Data System (ADS)

    Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Arnaud, M.; Arroja, F.; Ashdown, M.; Aumont, J.; Baccigalupi, C.; Ballardini, M.; Banday, A. J.; Barreiro, R. B.; Bartolo, N.; Battaner, E.; Benabed, K.; Benoît, A.; Benoit-Lévy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bock, J. J.; Bonaldi, A.; Bonavera, L.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Boulanger, F.; Bucher, M.; Burigana, C.; Butler, R. C.; Calabrese, E.; Cardoso, J.-F.; Catalano, A.; Challinor, A.; Chamballu, A.; Chary, R.-R.; Chiang, H. C.; Christensen, P. R.; Church, S.; Clements, D. L.; Colombi, S.; Colombo, L. P. L.; Combet, C.; Contreras, D.; Couchot, F.; Coulais, A.; Crill, B. P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Désert, F.-X.; Diego, J. M.; Dole, H.; Donzelli, S.; Doré, O.; Douspis, M.; Ducout, A.; Dupac, X.; Efstathiou, G.; Elsner, F.; Enßlin, T. A.; Eriksen, H. K.; Fergusson, J.; Finelli, F.; Forni, O.; Frailis, M.; Fraisse, A. A.; Franceschi, E.; Frejsel, A.; Frolov, A.; Galeotta, S.; Galli, S.; Ganga, K.; Gauthier, C.; Giard, M.; Giraud-Héraud, Y.; Gjerløw, E.; González-Nuevo, J.; Górski, K. M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Gudmundsson, J. E.; Hamann, J.; Handley, W.; Hansen, F. K.; Hanson, D.; Harrison, D. L.; Henrot-Versillé, S.; Hernández-Monteagudo, C.; Herranz, D.; Hildebrandt, S. R.; Hivon, E.; Hobson, M.; Holmes, W. A.; Hornstrup, A.; Hovest, W.; Huang, Z.; Huffenberger, K. M.; Hurier, G.; Jaffe, A. H.; Jaffe, T. R.; Jones, W. C.; Juvela, M.; Keihänen, E.; Keskitalo, R.; Kim, J.; Kisner, T. S.; Kneissl, R.; Knoche, J.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lähteenmäki, A.; Lamarre, J.-M.; Lasenby, A.; Lattanzi, M.; Lawrence, C. R.; Leonardi, R.; Lesgourgues, J.; Levrier, F.; Lewis, A.; Liguori, M.; Lilje, P. B.; Linden-Vørnle, M.; López-Caniego, M.; Lubin, P. M.; Ma, Y.-Z.; Macías-Pérez, J. F.; Maggio, G.; Maino, D.; Mandolesi, N.; Mangilli, A.; Maris, M.; Martin, P. G.; Martínez-González, E.; Masi, S.; Matarrese, S.; McGehee, P.; Meinhold, P. R.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mitra, S.; Miville-Deschênes, M.-A.; Molinari, D.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Moss, A.; Münchmeyer, M.; Munshi, D.; Murphy, J. A.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C. B.; Nørgaard-Nielsen, H. U.; Noviello, F.; Novikov, D.; Novikov, I.; Oxborrow, C. A.; Paci, F.; Pagano, L.; Pajot, F.; Paladini, R.; Pandolfi, S.; Paoletti, D.; Pasian, F.; Patanchon, G.; Pearson, T. J.; Peiris, H. V.; Perdereau, O.; Perotto, L.; Perrotta, F.; Pettorino, V.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Popa, L.; Pratt, G. W.; Prézeau, G.; Prunet, S.; Puget, J.-L.; Rachen, J. P.; Reach, W. T.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renault, C.; Renzi, A.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Rossetti, M.; Roudier, G.; Rowan-Robinson, M.; Rubiño-Martín, J. A.; Rusholme, B.; Sandri, M.; Santos, D.; Savelainen, M.; Savini, G.; Scott, D.; Seiffert, M. D.; Shellard, E. P. S.; Shiraishi, M.; Spencer, L. D.; Stolyarov, V.; Stompor, R.; Sudiwala, R.; Sunyaev, R.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J. A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Trombetti, T.; Tucci, M.; Tuovinen, J.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vielva, P.; Villa, F.; Wade, L. A.; Wandelt, B. D.; Wehus, I. K.; White, M.; Yvon, D.; Zacchei, A.; Zibin, J. P.; Zonca, A.

    2016-09-01

    We present the implications for cosmic inflation of the Planck measurements of the cosmic microwave background (CMB) anisotropies in both temperature and polarization based on the full Planck survey, which includes more than twice the integration time of the nominal survey used for the 2013 release papers. The Planck full mission temperature data and a first release of polarization data on large angular scales measure the spectral index of curvature perturbations to be ns = 0.968 ± 0.006 and tightly constrain its scale dependence to dns/ dlnk = -0.003 ± 0.007 when combined with the Planck lensing likelihood. When the Planck high-ℓ polarization data are included, the results are consistent and uncertainties are further reduced. The upper bound on the tensor-to-scalar ratio is r0.002< 0.11 (95% CL). This upper limit is consistent with the B-mode polarization constraint r< 0.12 (95% CL) obtained from a joint analysis of the BICEP2/Keck Array and Planck data. These results imply that V(φ) ∝ φ2 and natural inflation are now disfavoured compared to models predicting a smaller tensor-to-scalar ratio, such as R2 inflation. We search for several physically motivated deviations from a simple power-law spectrum of curvature perturbations, including those motivated by a reconstruction of the inflaton potential not relying on the slow-roll approximation. We find that such models are not preferred, either according to a Bayesian model comparison or according to a frequentist simulation-based analysis. Three independent methods reconstructing the primordial power spectrum consistently recover a featureless and smooth PR(k) over the range of scales 0.008 Mpc-1 ≲ k ≲ 0.1 Mpc-1. At large scales, each method finds deviations from a power law, connected to a deficit at multipoles ℓ ≈ 20-40 in the temperature power spectrum, but at an uncompelling statistical significance owing to the large cosmic variance present at these multipoles. By combining power spectrum and non-Gaussianity bounds, we constrain models with generalized Lagrangians, including Galileon models and axion monodromy models. The Planck data are consistent with adiabatic primordial perturbations, and the estimated values for the parameters of the base Λ cold dark matter (ΛCDM) model are not significantly altered when more general initial conditions are admitted. In correlated mixed adiabatic and isocurvature models, the 95% CL upper bound for the non-adiabatic contribution to the observed CMB temperature variance is | αnon - adi | < 1.9%, 4.0%, and 2.9% for CDM, neutrino density, and neutrino velocity isocurvature modes, respectively. We have tested inflationary models producing an anisotropic modulation of the primordial curvature power spectrum findingthat the dipolar modulation in the CMB temperature field induced by a CDM isocurvature perturbation is not preferred at a statistically significant level. We also establish tight constraints on a possible quadrupolar modulation of the curvature perturbation. These results are consistent with the Planck 2013 analysis based on the nominal mission data and further constrain slow-roll single-field inflationary models, as expected from the increased precision of Planck data using the full set of observations.

  9. Kharkiv Meteor Radar System (the XX Age)

    NASA Astrophysics Data System (ADS)

    Kolomiyets, S. V.

    2012-09-01

    Kharkiv meteor radar research are of historic value (Kolomiyets and Sidorov 2007). Kharkiv radar observations of meteors proved internationally as the best in the world, it was noted at the IAU General Assembly in 1958. In the 1970s Kharkiv meteor automated radar system (MARS) was recommended at the international level as a successful prototype for wide distribution. Until now, this radar system is one of the most sensitive instruments of meteor radars in the world for astronomical observations. In 2004 Kharkiv meteor radar system is included in the list of objects which compose the national property of Ukraine. Kharkiv meteor radar system has acquired the status of the important historical astronomical instrument in world history. Meteor Centre for researching meteors in Kharkiv is a analogue of the observatory and performs the same functions of a generator and a battery of special knowledge and skills (the world-famous studio). Kharkiv and the location of the instrument were brand points on the globe, as the place where the world-class meteor radar studies were carried out. They are inscribed in the history of meteor astronomy, in large letters and should be immortalized on a world-wide level.

  10. AUTOMOTIVE DIESEL MAINTENANCE 2. UNIT XX, TROUBLESHOOTING ELECTRICAL SYSTEMS.

    ERIC Educational Resources Information Center

    Minnesota State Dept. of Education, St. Paul. Div. of Vocational and Technical Education.

    THIS MODULE OF A 25-MODULE COURSE IS DESIGNED TO ACQUAINT THE TRAINEE WITH TROUBLESHOOTING PROCEDURES FOR DIESEL ENGINE ELECTRICAL SYSTEMS. TOPICS ARE (1) TROUBLESHOOTING ELECTRICAL SYSTEMS (INTRODUCTION), (2) TOOLS AND INSTRUMENTS FOR TROUBLESHOOTING, (3) THE BATTERY, (4) PERIODIC BATTERY SERVICING, (5) THE DC CHARGING SYSTEM, (6) PERIODIC…

  11. The Evolution from Generation to Post-XX

    ERIC Educational Resources Information Center

    Feng, Zhao

    2011-01-01

    Young people represent the future, and youth is an eternal topic. In the 1970s when the American anthropologist Margaret Mead published her famous work "Generation Gap," research on generations gained sudden popularity worldwide, and ever since the 1980s when "Generation Gap" was brought to China, research by scholars in this…

  12. XX1 Asian chestnut gall wasp (Dryocosmus kuriphilus) (Hymenoptera: Cynipidae)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The Asian chestnut gall wasp, Dryocosmus kuriphilus, is an invasive pest of chestnut in Japan, Europe, and the United States. D. kuriphilus induces formation of galls on all chestnut species. Damage caused by galling reduces commercial chestnut yields and threatens restoration of American chestnut i...

  13. The Path of Carbon in Photosynthesis XX. The Steady State

    DOE R&D Accomplishments Database

    Calvin, M.; Massini, Peter

    1952-09-01

    The separation of the phenomenon of photosynthesis in green plants into a photochemical reaction and into the light-dependent reduction of carbon dioxide is discussed, The reduction of carbon dioxide and the fate of the assimilated carbon were investigated with the help of the tracer technique (exposure of the planks to the radioactive C{sup 14}O{sub 2}) and of paper chromatography. A reaction cycle is proposed in which phosphoglyceric acid is the first isolable assimilations product. Analyses of the algal extracts which had assimilated radioactive carbon dioxide in a stationary condition ('steady-state' photosynthesis) for a long time provided further information concerning the proposed cycle and permitted the approximate estimation, for a number of compounds of what fraction of each compound was taking part in the cycle. The earlier supposition that light influences the respiration cycle was confirmed. The possibility of the assistance of {alpha}-lipoic acid, or of a related substance, in this influence and in the photosynthesis cycle, is discussed.

  14. Chapter XX: POLYMODAL SENSORY INTEGRATION IN RETINAL GANGLION CELLS

    PubMed Central

    Križaj, David

    2016-01-01

    An animal's ability to perceive the external world is conditioned by its capacity to extract and encode specific features of the visual image. The output of the vertebrate retina is not a simple representation of the 2D visual map generated by photon absorptions in the photoreceptor layer. Rather, spatial, temporal, direction selectivity and color “dimensions” of the original image are distributed in the form of parallel output channels mediated by distinct retinal ganglion cell (RGC) populations. We propose that visual information transmitted to the brain includes additional, light-independent, inputs that reflect the functional states of the retina, anterior eye and the body. These may include the local ion microenvironment, glial metabolism and systemic parameters such as intraocular pressure, temperature and immune activation which act on ion channels that are intrinsic to RGCs. We particularly focus on light-independent mechanical inputs that are associated with physical impact, cell swelling and intraocular pressure as excessive mechanical stimuli lead to the counterintuitive experience of “pressure phosphenes” and/or debilitating blinding disease such as glaucoma and diabetic retinopathy. We point at recently discovered retinal mechanosensitive ion channels as examples through which molecular physiology brings together Greek phenomenology, modern neuroscience and medicine. Thus, RGC output represents a unified picture of the embodied context within which vision takes place. PMID:26427477

  15. Wood Anatomy of the Neotropical Sapotaceae. XX. Manilkara

    DTIC Science & Technology

    1981-06-01

    were placed in synonomy under Manilkara mayarensis (Ekm.) Cronq. (3). In his studies of the " Sapodilla -Nispero complex," Gilly (7) created four new...new species from Haiti. Trop. Woods 71:3-6. 7. Gilly, Charles L. 1943. Studies in the Sapotaceae. II. The Sapodilla -Nispero complex. Trop. Woods 73:1

  16. Vulvar fetal rhabdomyoma mimicking 46XX sex differentiation disorder.

    PubMed

    Martos-Moreno, Gabriel Ángel; de Prada, Inmaculada; Riñón, Cristina; Argente, Jesús

    2016-02-01

    Rhabdomiomas are rare mesenchymal benign tumors of striated muscle origin. Setting aside the cardiac (most atrial) rhabdomiomas typically associated to neurocutaneous syndromes (tuberous sclerosis), extracardiac rhabdomyomas appear clinically as a subcutaneous nodule or as a submucosal polypoid lesion. Among them, three main histologic subtypes can be differentiated on the basis of the degree of tumor differentiation: 1) fetal rhabdomioma, usually diagnosed during childhood and almost exclusively located in the in the head and neck region with rare reports in other locations; 2) adult rhabdomioma; and 3) genital rhabdomioma, reported to occur in the lower genital tract of young and middle-aged women and, exceptionally, in children (5).

  17. Communications-Electronics Utilization Field AFSC 30XX.

    DTIC Science & Technology

    1984-08-01

    needed modification in the type and amount of electronics principles training given to entry-level officers. This finding has not changed over the...intervening 10 years. The 1984 survey indicates a need to review the electronics principles blocks of instruction. While there can be no argument that

  18. ICPEAC XX: A Retro- and Pro-Spective Analysis

    SciTech Connect

    Datz, S.

    1997-12-31

    There is something magical about ``round birthdays.`` They make one stop and think about where he is, how he got there, and where he is going. The same is apparently true of conferences, especially those like ICPEAC which represent the periodic coming together of a broad range of scientists in a reasonably well-defined discipline. This Vienna conference is the 20th in the ICPEAC series, and a retro- and pro-spective analysis seems appropriate. At the first ICPEAC in New York (1958), there were about 50 participants. In Vienna (1997), there were more than 800 participants. How do we account for this growth? ICPEAC is one of the most democratic conferences of its size. For example, input from a general committee of 50 representing the many geographic and sub- disciplinary areas gives continuous refreshment of ideas for the invited program. And, as in any democracy, there is a constant state of turmoil and self doubt. After all, atomic collisions is a ``mature`` field, and was a ``mature`` field at the time of the first ICPEAC in 1958, 50 what can one expect in new developments? This self doubt is best expressed in the comment of Ben Bederson (the ``Father of ICPEAC``) following the second in Boulder, Colorado, in 1961: ``This conference is the second in a series of informal meetings organized by a group of workers in the general field of electronic and atomic collisions. The first such meeting was held at New York University in 1958, and we will probably continue to meet at irregular intervals in the future....`` As part of my ``keynote`` talk at the New York ICPEAC XVI in 1989, I gave a brief history of the conference which we can build on to round things off for our twentieth.

  19. Treating epilepsy in Italy between XIX and XX century.

    PubMed

    Tagarelli, Giuseppe; Tagarelli, Antonio; Liguori, Maria; Piro, Anna

    2013-01-30

    Epilepsy is a neurological disorder which has been recognized since antiquity. This paper evaluates the prophylactic and therapeutic remedies used by folk medicine to cure epilepsy in Italy. The data has been collected by reviewing written sources of physicians, ethnographers, folklorists between the late nineteenth and mid twentieth century. This approach leads to unearthing of 78 heterogeneous healing methods that have been divided into 16 (20%) magical, 20 (26%) religious and 42 (54%) natural remedies. The latter has been subdivided into 18 (43%) animal remedies, 17 (40%) plant remedies and 7 (17%) other remedies. Religious and magical remedies were used with the conviction that they would be able to provide recovery from epilepsy and to ward off evil spirits which had taken possession of the sick. Interestingly, the herbal remedies highlighted 12 (70%) plants that play or might play an important role with respect to the mechanisms that generate the epileptic seizures. This leads us to reconsider the historical significance of folk medicine, too often it is underestimated owing to its use of ineffective remedies, born of incompetence and superstition.

  20. The need for a paradigm shift in toxicology xx.

    EPA Science Inventory

    This manuscript briefly reviews the impact of the NAS report “Toxicity Testing in the 21st Century: A Vision and A Strategy” and it’s potential impact on the field of toxicology. ). This report provides a strategic and tactical framework for attaining the goals of deter...

  1. Speckle Interferometry at the U.S. Naval Observatory. XX

    NASA Astrophysics Data System (ADS)

    Hartkopf, William I.; Mason, Brian D.

    2015-10-01

    Results are presented of 4222 intensified CCD observations of double stars, made with the 26 inch refractor of the U.S. Naval Observatory in 2013 and 2014. These observations are averaged into 2335 mean relative positions and range in separation from 0.″53 to 83.″90, with a median separation of 11.″42. This is the 20th in this series of papers and covers the period 2013 January 4 through 2014 December 18. Also presented are 13 pairs which are measured for the first time, 12 pairs which appear to be lost, linear elements for 17 pairs, and orbital elements for five additional pairs. Finally, we investigated apparent systematic residuals to earlier measures in this series, and modify scale factors for closer pairs observed between 1990 and the present.

  2. [The medicine in Mexico in the XX century].

    PubMed

    Flisser, Ana

    2009-01-01

    The end of the 19th and the beginning of the 20th century constitute a breakthrough in medicine. The Industrial Revolution was soon followed by a revolution in medicine characterized by a similar pattern where novel technology was produced. This initiated the transformation of medicine as a science and the establishment of medical specialties as we know them to date. Mexicans physicians must be commended for quickly adapting to this new way of thinking and practicing medicine. Important changes in clinical practice and in the medical community took place and were associated with the creation of several medical institutions. The field of public health grew as a medical concept focused on the individual and the population.

  3. Oral Histories in Meteoritics and Planetary Science - XX: Dale Cruikshank

    NASA Astrophysics Data System (ADS)

    Sears, Derek W. G.

    2013-04-01

    In this interview, Dale Cruikshank (Fig. 1) explains how as an undergraduate at Iowa State University he was a summer student at Yerkes Observatory where he assisted Gerard Kuiper in work on his Photographic Lunar Atlas. Upon completing his degree, Dale went to graduate school at the University of Arizona with Kuiper where he worked on the IR spectroscopy of the lunar surface. After an eventful 1968 trip to Moscow via Prague, during which the Soviets invaded Czechoslovakia, Dale assumed a postdoc position with Vasili Moroz at the Sternberg Astronomical Institute and more observational IR astronomy. Upon returning to the United States and after a year at Arizona, Dale assumed a position at the University of Hawai'i that he held for 17 years. During this period Dale worked with others on thermal infrared determinations of the albedos of small bodies beyond the asteroid Main Belt, leading to the recognition that low-albedo material is prevalent in the outer solar system that made the first report of complex organic solids on a planetary body (Saturn's satellite Iapetus). After moving to Ames Research Center, where he works currently, he continued this work and became involved in many outer solar system missions. Dale has served the community through his involvement in developing national policies for science-driven planetary exploration, being chair of the DPS 1990-1991 and secretary/treasurer for 1982-1985. He served as president of Commission 16 (Physics of Planets) of the IAU (2001-2003). He received the Kuiper prize in 2006.

  4. Conducting Slug Tests in Mini-Piezometers: B.G. Fritz Ground Water xx, no. x: x-xx

    SciTech Connect

    Fritz, Bradley G.; Mackley, Rob D.; Arntzen, Evan V.

    2015-03-26

    Slug tests performed using mini-piezometers with diameters as small as 0.43 cm can provide a cost effective tool for hydraulic characterization. We evaluated the hydraulic properties of the apparatus in an infinite hydraulic conductivity environment and compared those results with field tests of mini-piezometers installed into locations with varying hydraulic properties. Based on our evaluation, slug tests conducted in mini-piezometers using the fabrication and installation approach described here are effective within formations where the hydraulic conductivity is less than 1 x 10-3 cm/s. While these constraints limit the potential application of this method, the benefits to this approach are that the installation, measurement and analysis is extremely cost effective, and the installation can be completed in areas where other (larger diameter) methods might not be possible. Additionally, this methodology could be applied to existing mini-piezometers previously installed for other purposes. Such analysis of existing installations could be beneficial in interpreting previously collected data (e.g. water quality data or hydraulic head data).

  5. 75 FR 3144 - Airworthiness Directives; Sicma Aero Seat 90xx and 92xx Series Passenger Seats, Installed on, But...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-20

    ...) 2 54 03 39 39; fax +33 (0) 2 54 03 15 16; e-mail: customerservices@sicma.zodiac.com ; Internet http://www.sicma.zodiac.com/en/ . (3) You may review copies of the service information at the FAA,...

  6. 46 CFR Appendix B to Part 535 - Monitoring Report and Instructions

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... capacity (B)Utilization Carrier A : Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Carrier B: Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Etc. . . . (C) Narrative statement on significant reductions in vessel capacity...

  7. 46 CFR Appendix A to Part 535 - Information Form and Instructions

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Time Period: (A)Vessel Capacity (B)Utilization Carrier A Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Carrier B Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Etc. . . . (C) Narrative statement on significant changes...

  8. 46 CFR Appendix B to Part 535 - Monitoring Report and Instructions

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... capacity (B)Utilization Carrier A : Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Carrier B: Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Etc. . . . (C) Narrative statement on significant reductions in vessel capacity...

  9. 46 CFR Appendix A to Part 535 - Information Form and Instructions

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Time Period: (A)Vessel Capacity (B)Utilization Carrier A Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Carrier B Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Etc. . . . (C) Narrative statement on significant changes...

  10. 46 CFR Appendix B to Part 535 - Monitoring Report and Instructions

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... capacity (B)Utilization Carrier A : Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Carrier B: Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Etc. . . . (C) Narrative statement on significant reductions in vessel capacity...

  11. 46 CFR Appendix A to Part 535 - Information Form and Instructions

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Time Period: (A)Vessel Capacity (B)Utilization Carrier A Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Carrier B Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Etc. . . . (C) Narrative statement on significant changes...

  12. Gonadal dysgenesis, Turner syndrome with 46,XX,del(18p)3

    SciTech Connect

    Telvi, L.; Ion, R.; Bernheim, A.

    1994-09-01

    The authors report a case of a female infant with gonadal dysgenesis, clinical features of Turner syndrome and a de novo del(18p). The factors controlling gonadal dysgenesis and Turner syndrome are unknown to date. The genes involved could be located not only on X chromosome but also on autosomes. The present case suggests that one of these genes is situated on the short arm of chromosome 18. We conclude that patients with del(18p) syndrome should be evaluated for gonadal dysgenesis.

  13. The Herschel Virgo Cluster Survey. XX. Dust and gas in the foreground Galactic cirrus

    NASA Astrophysics Data System (ADS)

    Bianchi, S.; Giovanardi, C.; Smith, M. W. L.; Fritz, J.; Davies, J. I.; Haynes, M. P.; Giovanelli, R.; Baes, M.; Bocchio, M.; Boissier, S.; Boquien, M.; Boselli, A.; Casasola, V.; Clark, C. J. R.; De Looze, I.; di Serego Alighieri, S.; Grossi, M.; Jones, A. P.; Hughes, T. M.; Hunt, L. K.; Madden, S.; Magrini, L.; Pappalardo, C.; Ysard, N.; Zibetti, S.

    2017-01-01

    We study the correlation between far-infrared/submm dust emission and atomic gas column density in order to derive the properties of the high Galactic latitude, low density, Milky Way cirrus in the foreground of the Virgo cluster of galaxies. Dust emission maps from 60 to 850 μm are obtained from observations with the Spectral and Photometric Imaging Receiver (SPIRE) and carried out within the Herschel Virgo Cluster Survey (HeViCS); these are complemented by IRAS and Planck maps. Data from the Arecibo legacy Fast ALFA Survey is used to derive atomic gas column densities for two broad velocity components: low and intermediate velocity clouds. Dust emissivities are derived for each gas component and each far-infrared/submm band. For the low velocity clouds, we measure an average emissivity ɛLVCν = (0.79 ± 0.08) × 10-20 MJy sr-1 cm2 at 250 μm. After fitting a modified blackbody to the available bands, we estimated a dust absorption cross section of τLVCν/NH i = (0.49 ± 0.13) × 10-25 cm2 H-1 at 250 μm (with dust temperature T = 20.4 ± 1.5 K and spectral index β = 1.53 ± 0.17). The results are in excellent agreement with those obtained by Planck over a much larger coverage of the high Galactic latitude cirrus (50% of the sky versus 0.2% in our work). For dust associated with intermediate velocity gas, we confirm earlier Planck results and find a higher temperature and lower emissivity and cross section. After subtracting the modeled components, we find regions at scales smaller than 20' in which the residuals deviate significantly from the average scatter, which is dominated by cosmic infrared background. These large residuals are most likely due to local variations in the cirrus dust properties or to high-latitude molecular clouds with average NH2 ≲ 1020 cm-2. We find no conclusive evidence for intracluster dust emission in Virgo. Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA.Final reduced data (FITS) are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/597/A130

  14. 78 FR 10003 - Proposed Collection; Comment Request for Notice 2009-XX (NOT-151370-08)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-12

    ... for Carbon Dioxide Sequestration under Section 45Q. DATES: Written comments should be received on or...: Credit for Carbon Dioxide Sequestration under Section 45Q OMB Number: 1545-2153. Notice Number: Notice... issuance of regulations, relating to the credit for carbon dioxide sequestration (CO 2 sequestration...

  15. Assessment of oceanity and continentality conditions of the XX Century in the Iberian Peninsula

    NASA Astrophysics Data System (ADS)

    Andrade, Cristina; Corte-Real, João

    2016-04-01

    The oceanity and continentality conditions clearly influence the climate of a region. Seeking at understanding these influences on the Iberian Peninsula climate, the spatial distributions of air temperature, precipitation and five climatic indices are analysed in the period between 1901 and 2012 and in three sub-periods (1901-40, 1941-80 and 1981-2012). This study aims at investigating the Xerothermic index of Gaussen and the continental and oceanic characteristics of the Iberian climate by using Conrad-Pollak and Johansson Continentality Indices, as well as Kerner and Marsz Oceanity Indices. Gridded air temperature and precipitation datasets are used on a monthly basis. Results reveal hyper-oceanic (maritime) characteristics in the northernmost portion of Iberia, continental in the inner region comprising Extremadura, Castile-La Mancha and Andalusia, and maritime characteristics in between. It is worth mentioning that within these regions the maritime (continental) characteristics become weaker (stronger) between 1981 and 2012. Statistically significant linear trends show an increase in both temperature (2-4°C) and on continental influences in the northwestern and southeastern regions of Iberia for the entire period. Statistically significant correlations are also found between the Johansson Continentality Index and both Conrad-Pollak and Marsz Oceanity Indices at a 95% confidence level, revealing a good agreement of results among these indices. This work is supported by: European Investment Funds by FEDER/COMPETE/POCI-Operational Competitiveness and Internationalization Programme, under Project POCI-01-0145-FEDER-006958 and National Funds by FCT - Portuguese Foundation for Science and Technology, under the project UID/AGR/04033.

  16. 8111/8116 Security Police Staff Officers 8121/8124 Security Police Officers AFSC: 81XX

    DTIC Science & Technology

    1992-02-01

    4. 04 S -4C S. 4.4 .4.C At Oq- U o C u..444 a4 x 01 C C -0 - P1 .A.- !4 4q0 L A. aU LU I a4 a C0 A.XV a L 0 1 -U S.0.0 4 CL A40 0NC 4.a SC C a E43 C~ z...L - - R~ . ( *U # ACCa .4 % 40 a - 4- 1 4 4-L 0 *-46.40 50 a .40C CL 0 Ŕ 1 0. 0 OUUCC>CU.U0C4-LSa LC .CaC CW~ift-4C .4,4f L .4 -S(( a-..CA a COC *-. 4...Ni .C! o ~ a -N 4 Ř’,-4 .C.M-M4"-40.M.𔃾 M M -4 M4. .4 P1 M M4 .4.M4.󈧒 14 C L me a > 0. IL 0 c C. CD𔃺A1 a 4’L 0. C%-’ti "~nn =O~ 0N N? - 0W 0% 14

  17. Hydrosweep Measurements During the Expedition ARK XX-2 to Lena Trough and Western Gakkel Ridge

    NASA Astrophysics Data System (ADS)

    Gauger, S.; Kohls, T.; Roeber, S.; Snow, J.

    2004-12-01

    The region of Lena Trough and Western Gakkel Ridge in the Arctic Ocean was the object of an expedition in the summer of 2004. This region is of particular geoscientific interest because of its extremely slow spreading rates and the variety of morphologic forms that are produced in this tectonic environment. Therefore, the multibeam measurement system was of particular importance to the scientific goals of the cruise. The main characteristic of the Hydrosweep DS-2 deep-water sounding system aboard RV Polarstern is the 90° or 120° coverage angle in which the seafloor is depicted with 59 specific values for water depths perpendicular to the ship's long axis. The accuracy of the measurement is approx. 1% of water depth, the frequency of the acoustic signal is 15.5 kHz. The refraction of the sonar beams was corrected by automatic crossfan calibration. By regular transmission and measurement of a sweep profile in the ship's longitudinal direction and comparison of the slant beams with the vertical beam, the mean sound velocity over the vertical water column is determined and is used for the depth computation. The data collected include depth, sidescan (2048 values per scan), and backscatter information on each of the 59 beams. During this cruise, the Lena Trough was surveyed systematically for the first time by a multibeam sonar system. The recorded area has an expanse of approx. 100000 km2 and connects previously mapped areas of the Eurasian - North-American plate boundary between Fram Strait and Gakkel Ridge. The region of Western Gakkel Ridge, mapped in 2001 (AMOR-Expedition) by RV Polarstern and USCGC Healy (USA), was extended by two more profiles (each 220 km long) along the ridge. In order to produce working maps for the expedition, the multibeam sonar data were gridded with a spacing of 50 m, producing plots with various contour line intervals. For further morphological interpretation of Lena Trough and Gakkel Ridge slope magnitude maps, slope direction maps and two-dimensional slope histograms were produced. They show clearly the predominant slope direction and are helpful in distinction between sediment basins, volcanos and ridge flanks.

  18. Quality of life of patients with 46,XX and 46,XY disorders of sex development.

    PubMed

    Amaral, Rita Cassia; Inacio, Marlene; Brito, Vinicius N; Bachega, Tania A S S; Domenice, Sorahia; Arnhold, Ivo J P; Madureira, Guiomar; Gomes, Larissa; Costa, Elaine M F; Mendonca, Berenice B

    2015-02-01

    Disorders of sex development (DSD) result from abnormalities in the complex process of sex determination and differentiation. An important consideration to guide the assignment of social sex in newborns with ambiguous genitalia is the quality of life (QoL) of these patients in adulthood. The rarity of most DSD conditions makes it difficult to conduct a long-term follow-up of affected patients through adulthood. This review of papers on the QoL of DSD patients evaluated in developing and developed countries by qualitative and quantitative instruments revealed a large spectrum of QoL, ranging from very poor to similar to, or even better than, the normal population. A more adequate QoL was found in patients from tertiary centres, indicating that the medical care of DSD patients should be multidisciplinary and carried out by specialized teams.

  19. Historical sources on climate and extreme events before XX century in Calabria (Italy)

    NASA Astrophysics Data System (ADS)

    Aurora Pasqua, Angela; Petrucci, Olga

    2014-05-01

    Damaging Hydrogeological Events (DHEs) are defined as the occurrence of destructive phenomena, such as landslides and floods, triggered by extreme rain events. Due to the huge damage that they can cause to people and properties, DHEs are often described in a wide series of historical sources. The historical series of DHEs that affected a study region can supply useful information about the climatic trend of the area. Moreover, it can reveals temporal and spatial increases in vulnerability affecting sectors where urbanization increased throughout the time. On the other side, it can highlight further vulnerability variations occurred throughout the decades and related to specific defensive measures undertaken (or abandoned) in order to prevent damage caused by either landslides or floods. We present the historical series of catastrophic DHEs which affected a Mediterranean region named Calabria that is located in southern Italy. Data presented came from the database named ASICal (the Italian acronym of historically flooded areas in Calabria) that has been built at the beginning of 2000 at CNR-IRPI of Cosenza and that has been continuously updated since then. Currently, this database includes more than 11,000 records about floods and landslides which have been occurred in Calabria since the XVI century. These data came from different information sources as newspapers, archives of regional and national agencies, scientific and technical reports, on-site surveys reports and so on. ASICal is constantly updated. The updating concerns both current DHEs that every years affect the region, and the results of specific historical research that we regularly perform in order to fill data gaps for older epochs. In this work we present the result of a recent survey carried out in some regional public libraries focusing on the early-mid XIX century. The type of data sources available for the regional framework are described and a sketch of the DHEs trend during the last three centuries is presented. Moreover, a panoramic view of both proxy data and irregularly measured parameters concerning climatic trend of the region obtained from the analyzed historical sources is also shown.

  20. X-Ray Toolkit (XTK) Touch App v. 1.0.x.x

    SciTech Connect

    Garretson, Justin; Hobart, Clinton; Rael, Reymundo; Eldridge, Bryce

    2016-01-20

    Windows 8 App for use in viewing, enhancing, and manipulating x-ray images. Intended for use by state/local government, federal agencies, and military in explosive ordinance disposal (EOD) applications.

  1. 76 FR 10072 - Proposed Generic Communications; Draft NRC Regulatory Issue Summary 2011-XX, Adequacy of Station...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-23

    ... Electric Distribution System Voltages; Reopening of Public Comment Period AGENCY: Nuclear Regulatory..., Adequacy of Station Electric Distribution System Voltages, closes on February 17, 2011. The purpose of this... February, 2011. For the Nuclear Regulatory Commission. Roy Mathew, Acting Branch Chief,...

  2. [Concept and history of public health in Mexico (XVIII to XX century)].

    PubMed

    Fierros Hernández, Arturo

    2014-01-01

    This paper is a brief history of public health. I review the concept of public health and its origins in the West, and also analyze the input of politics in the Mexican health system through the government of Porfirio Diaz.

  3. Training Extract AFSC 51XX Computer Systems Officer AFPT 90-51X-468.

    DTIC Science & Technology

    1983-06-01

    C 1 55. ANALYZE PROGRAM DUMPS .93 N.M 2.2 M.6 .3ES ANALYZ SYSTEM DUMPS ,93 N.M 2.2 6 .0 - 499 MARE ENTRIES ON SYSTEM FAILURE LOGS ,97 l*O 11*1 IN.3...2.2 . 5.3 .0 " 657 APPROVE OR DISAPPROVE SYSTEM DOCUMENTATION SUCH AS BAIA .16 .C .2 .0 .0 REOUOQCMCMTS DOCUMENTS (RD? OR SYSTEM SPECIFICATIONS SSI 660...9.1 3,7 A 971 ASSISTI COMPUTER OPERATORS IN FAILURE RECOVERY PROCEDURES .91 75.7 10.1 21. 7.1 I I.1 518R4 MARE TDY APRANSEMENTS SUCH AS BILLETING

  4. Analysis of The Xx Century Effusive Activity At Mount Etna To Assess The Potential Effusive Hazard.

    NASA Astrophysics Data System (ADS)

    Andronico, D.; Lodato, L.; Neri, M.

    We examined older documents and publications together with more recent and de- tailed reports related to the 20th century effusive activity (terminal and flank eruptions) at Mt. Etna, with the primary objective of creating a single data-base of volcanologi- cal data, at present lacking in the literature. The restitution in digital form of the maps of the lava fields allowed to measure, with great precision compared with previous estimations, the area and length of every lava flow, allowing improved estimates of volumes and effusive rates. The quantity and the quality of the collected bibliographic information of the studied eruptions improve progressively from the beginning of the century up to the present, and can be considered complete for the flank activity. The data of each single eruption have been inserted into a relational database, that pro- vides both ease of use and the potential of upgrading with information from new or more ancient eruptions. By examining the collected data (e.g. maximum length of lava flows, altitude reached, eruption duration) we obtained some useful relationships, that allowed us to characterise some eruption typologies at Etna. The improvement of the volcanic data related to the effusive activity of the last century represents an impor- tant contribution in terms of volcanic hazard, suggesting for example the areas most at risk by opening of eruptive fractures and lava covering. Statistical observations can be a useful contribution to the planning required by civil defense in a strongly urban- ized area, such as the etnean one; assessment hazard, in particular, should be focused particularly on the southeastern foot of the volcanic belt, in which the volcanic risk in- creases due to the presence of several populated centers that amount to approximately 500.000 people.

  5. [Clinical research XX. From clinical judgment to multiple logistic regression model].

    PubMed

    Berea-Baltierra, Ricardo; Rivas-Ruiz, Rodolfo; Pérez-Rodríguez, Marcela; Palacios-Cruz, Lino; Moreno, Jorge; Talavera, Juan O

    2014-01-01

    The complexity of the causality phenomenon in clinical practice implies that the result of a maneuver is not solely caused by the maneuver, but by the interaction among the maneuver and other baseline factors or variables occurring during the maneuver. This requires methodological designs that allow the evaluation of these variables. When the outcome is a binary variable, we use the multiple logistic regression model (MLRM). This multivariate model is useful when we want to predict or explain, adjusting due to the effect of several risk factors, the effect of a maneuver or exposition over the outcome. In order to perform an MLRM, the outcome or dependent variable must be a binary variable and both categories must mutually exclude each other (i.e. live/death, healthy/ill); on the other hand, independent variables or risk factors may be either qualitative or quantitative. The effect measure obtained from this model is the odds ratio (OR) with 95 % confidence intervals (CI), from which we can estimate the proportion of the outcome's variability explained through the risk factors. For these reasons, the MLRM is used in clinical research, since one of the main objectives in clinical practice comprises the ability to predict or explain an event where different risk or prognostic factors are taken into account.

  6. A Process Control System for Hewlett-Packard Series 21XX Computers.

    DTIC Science & Technology

    1980-08-01

    EXPERIMENT 0034 ILOG(3)no 0035 1LOG(4)u’) 0036 1Pa2 003? CALL LOGDA 0038 ISSFLŔ 0039 ILAST*O 0040 ISUPER =O 0041 HS-IPRM(4 0042 105 IFLGuO 0043 I ST=NS...0044 IF(:STAB(14,IST) GT.O)CALL INITL 0045 IF( ISSFL.GT.O)GO TO 110 0046 CALL IHSCB( IND) 0047 110 ISUPER =ILAST 0048 IF(ISUPER.LE.0)GO TO 111 0049 IF...ISCB(4,I3UPER).HE.INnD)ISCB(4, ISUPER )=IND 0050 111 ILAST=INDC 0051 IF( ISTAB( 13,1ST).EQ 0 )GO TO 120 0052 CALL INSCB( INDSS) B-23 0053 C SET UP COUNT

  7. Disaster Preparedness Utilization Field/Disaster Preparedness Career Ladder, AFSCs 05XX/242X0

    DTIC Science & Technology

    1988-11-01

    plans prepare briefings 7 w pm z 0 g x I Ia x It) 0 a C)P ~0 0 I 0 zz 0l I iilE~ I~~II4 oi CA I-- -0Ci ~ 0D 40 r-~a P- A.. LL * S ’ D. 0 rIJ V 13 wi...C-4 w 4 CAC C Li ~ C I--lU U) 0 2CV))O ACJ .J)S Sil SS.J ~ CI #A 0. 0 C w . w 4JL~ o CD 3 0 LL . LI W -o 0q L0r D C )a LO 00 LO V) -4CJ W- c- CD.)C...2ciJfr C CD 40.U oc LL -r o OR t a LLLa Q CD La 2 4V) CL.2 CD w r La1 O2 - 04 L.0 inLa 2i V 04 . t2~~~ ccC)- L CL ac LI w Y = LL ~. V)- - CD i C 4 fw qr

  8. THE ANGLO-AUSTRALIAN PLANET SEARCH. XX. A SOLITARY ICE-GIANT PLANET ORBITING HD 102365

    SciTech Connect

    Tinney, C. G.; Wittenmyer, Robert A.; Bailey, Jeremy; Butler, R. Paul; Jones, Hugh R. A.; O'Toole, Simon; Carter, Brad D.

    2011-02-01

    We present 12 years of precision Doppler data for the very nearby G3 star HD 102365, which reveals the presence of a Neptune-like planet with a 16.0 M{sub Earth} minimum mass in a 122.1 day orbit. Very few 'Super Earth' planets have been discovered to date in orbits this large and those that have been found reside in multiple systems of between three and six planets. HD 102365 b, in contrast, appears to orbit its star in splendid isolation. Analysis of the residuals to our Keplerian fit for HD 102365 b indicates that there are no other planets with minimum mass above 0.3 M{sub Jup} orbiting within 5 AU and no other 'Super Earths' more massive than 10 M{sub Earth} orbiting at periods shorter than 50 days. At periods of less than 20 days these limits drop to as low as 6 M{sub Earth}. There are now 32 exoplanets known with minimum mass below 20 M{sub Earth}, and interestingly the period distributions of these low-mass planets seem to be similar whether they orbit M-, K-, or G-type dwarfs.

  9. AESOP XX: summary of proceedings. [Gatlinburg, Tennessee, April 24 to 26, 1979

    SciTech Connect

    1980-03-01

    The 20th meeting of the Association for Energy Systems, Operations, and Programming (AESOP) was held in Gatlinburg, Tennessee, on April 24 to 26, 1979. Representatives of DOE Headquarters discussed the effects that new security and privacy regulations will have on automatic data processing operations. The status and future possibilities of the Business Management Information System (BMIS) were also discussed. Then representatives of various DOE offices and contractors presented reports on various topics. This report contains two-page summaries of the papers presented at the meeting. Session topics and titles of papers were as follows: Washington report (New ADP issues; BMIS: the Business Management Information System; Nuclear weapons and the computer); Improving the productivity of the computing analyst/programer (What productivity improvement tools are available; Rocky Flats experience with SDM/70; Albuquerque Operations Office experience with SDM/70; Planning and project management; Minicomputer standards and programer productivity; MRC productivity gains through applications development tools); User viewpoints and expectations of data processing (User perspectives on computer applications; User viewpoints on environmental studies; Planning and implementing a procurement system; Two sides of the DP coin); Data base management (Use of data base systems within DOE; Future trends in data base hardware; Future trends in data base software; Toward automating the data base design process); and Management discussions. Complete versions of three of the papers have already been cited in ERA. These can be located by reference to the entry CONF-790431-- in the Report Number Index. (RWR)

  10. Military Specification for Type 10XX Powder-Forged Weapon Components.

    DTIC Science & Technology

    1985-10-14

    6292-3 UNLSIFIED RRSCO- CR -50 ORRKICI-4-C-0245 F/G 11/6.2 2 I ihhhEhh irmmohhmhmhum I, 111112.2 I1.25 1 . 51IM NIII qp 4 I.~ - . 1 3 N OV 1985...CONTRACTOR REPORT ARSCD- CR -85008 !MILITARY SPECIFICATION FOR TYPE IOXX : POWDER-FORGED WEAPON COMPONENTS - .I-. - 5 ~FINAL TECHNICAL REPORT [ -- STEVEN...INSTRUCTiONS R R O iEEFORE COMPLETING FORM I. REPORT NUMBER 2. GOVT ACCESSION NQ. " E CiPIENT’. CATALOU NUMBLR Contractor Report ARSCD- CR -85008 4- TITLE (a"nd

  11. Planck early results. XX. New light on anomalous microwave emission from spinning dust grains

    NASA Astrophysics Data System (ADS)

    Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Arnaud, M.; Ashdown, M.; Aumont, J.; Baccigalupi, C.; Balbi, A.; Banday, A. J.; Barreiro, R. B.; Bartlett, J. G.; Battaner, E.; Benabed, K.; Benoît, A.; Bernard, J.-P.; Bersanelli, M.; Bhatia, R.; Bock, J. J.; Bonaldi, A.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Boulanger, F.; Bucher, M.; Burigana, C.; Cabella, P.; Cappellini, B.; Cardoso, J.-F.; Casassus, S.; Catalano, A.; Cayón, L.; Challinor, A.; Chamballu, A.; Chary, R.-R.; Chen, X.; Chiang, L.-Y.; Chiang, C.; Christensen, P. R.; Clements, D. L.; Colombi, S.; Couchot, F.; Coulais, A.; Crill, B. P.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; de Gasperis, G.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Delouis, J.-M.; Dickinson, C.; Donzelli, S.; Doré, O.; Dörl, U.; Douspis, M.; Dupac, X.; Efstathiou, G.; Enßlin, T. A.; Eriksen, H. K.; Finelli, F.; Forni, O.; Frailis, M.; Franceschi, E.; Galeotta, S.; Ganga, K.; Génova-Santos, R. T.; Giard, M.; Giardino, G.; Giraud-Héraud, Y.; González-Nuevo, J.; Górski, K. M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Hansen, F. K.; Harrison, D.; Helou, G.; Henrot-Versillé, S.; Herranz, D.; Hildebrandt, S. R.; Hivon, E.; Hobson, M.; Holmes, W. A.; Hovest, W.; Hoyland, R. J.; Huffenberger, K. M.; Jaffe, T. R.; Jaffe, A. H.; Jones, W. C.; Juvela, M.; Keihänen, E.; Keskitalo, R.; Kisner, T. S.; Kneissl, R.; Knox, L.; Kurki-Suonio, H.; Lagache, G.; Lähteenmäki, A.; Lamarre, J.-M.; Lasenby, A.; Laureijs, R. J.; Lawrence, C. R.; Leach, S.; Leonardi, R.; Lilje, P. B.; Linden-Vørnle, M.; López-Caniego, M.; Lubin, P. M.; Macías-Pérez, J. F.; MacTavish, C. J.; Maffei, B.; Maino, D.; Mandolesi, N.; Mann, R.; Maris, M.; Marshall, D. J.; Martínez-González, E.; Masi, S.; Matarrese, S.; Matthai, F.; Mazzotta, P.; McGehee, P.; Meinhold, P. R.; Melchiorri, A.; Mendes, L.; Mennella, A.; Mitra, S.; Miville-Deschênes, M.-A.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Munshi, D.; Murphy, A.; Naselsky, P.; Natoli, P.; Netterfield, C. B.; Nørgaard-Nielsen, H. U.; Noviello, F.; Novikov, D.; Novikov, I.; O'Dwyer, I. J.; Osborne, S.; Pajot, F.; Paladini, R.; Partridge, B.; Pasian, F.; Patanchon, G.; Pearson, T. J.; Peel, M.; Perdereau, O.; Perotto, L.; Perrotta, F.; Piacentini, F.; Piat, M.; Plaszczynski, S.; Platania, P.; Pointecouteau, E.; Polenta, G.; Ponthieu, N.; Poutanen, T.; Prézeau, G.; Procopio, P.; Prunet, S.; Puget, J.-L.; Reach, W. T.; Rebolo, R.; Reich, W.; Reinecke, M.; Renault, C.; Ricciardi, S.; Riller, T.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Rowan-Robinson, M.; Rubiño-Martín, J. A.; Rusholme, B.; Sandri, M.; Santos, D.; Savini, G.; Scott, D.; Seiffert, M. D.; Shellard, P.; Smoot, G. F.; Starck, J.-L.; Stivoli, F.; Stolyarov, V.; Stompor, R.; Sudiwala, R.; Sygnet, J.-F.; Tauber, J. A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Torre, J.-P.; Tristram, M.; Tuovinen, J.; Umana, G.; Valenziano, L.; Varis, J.; Verstraete, L.; Vielva, P.; Villa, F.; Vittorio, N.; Wade, L. A.; Wandelt, B. D.; Watson, R.; Wilkinson, A.; Ysard, N.; Yvon, D.; Zacchei, A.; Zonca, A.

    2011-12-01

    Anomalous microwave emission (AME) has been observed by numerous experiments in the frequency range ~10-60 GHz. Using Planck maps and multi-frequency ancillary data, we have constructed spectra for two known AME regions: the Perseus and ρ Ophiuchi molecular clouds. The spectra are well fitted by a combination of free-free radiation, cosmic microwave background, thermal dust, and electric dipole radiation from small spinning dust grains. The spinning dust spectra are the most precisely measured to date, and show the high frequency side clearly for the first time. The spectra have a peak in the range 20-40 GHz and are detected at high significances of 17.1σ for Perseus and 8.4σ for ρ Ophiuchi. In Perseus, spinning dust in the dense molecular gas can account for most of the AME; the low density atomic gas appears to play a minor role. In ρ Ophiuchi, the ~30 GHz peak is dominated by dense molecular gas, but there is an indication of an extended tail at frequencies 50-100 GHz, which can be accounted for by irradiated low density atomic gas. The dust parameters are consistent with those derived from other measurements. We have also searched the Planck map at 28.5 GHz for candidate AME regions, by subtracting a simple model of the synchrotron, free-free, and thermal dust. We present spectra for two of the candidates; S140 and S235 are bright Hii regions that show evidence for AME, and are well fitted by spinning dust models. Corresponding author: C. Dickinson, Clive.Dickinson@manchester.ac.uk

  12. Follow-Up Study of 1990 Dental Hygiene Graduates. Volume XX, No. 1.

    ERIC Educational Resources Information Center

    Holt, Marianne; Lucas, John A.

    In a continuing effort to measure the quality of their Dental Hygiene program, explore the need for changes, and substantiate the program's goals for accreditation standards, a follow-up study was conducted of the 1990 Dental Hygiene program graduates from William Rainey Harper (WRHC) College in Palatine, Illinois. A survey was mailed to all 30…

  13. Synthesis and characterization of noble metal borides: RuB{sub x}(x > 1)

    SciTech Connect

    Li, Zhifang; Zheng, Dafang; Ding, Zhanhui; Li, Yongfeng; Yao, Bin; Li, Yongsheng; Zhao, Xudong; Yu, Guichuan; Tang, Yang; Zheng, Weitao; Liu, Xiaoyang

    2016-02-15

    Highlights: • Hexagonal RuB{sub 1.1} were synthesized using ruthenium and boron powders as raw materials during ball milling process. • Orthorhombic RuB{sub 2} were synthesized under high pressure (5 GPa) and high temperature (1000 °C) conditions. • Hexagonal Ru{sub 2}B{sub 3} have been synthesized under 5 GPa and 1200 °C. - Abstract: Noble metal borides RuB{sub 1.1}, RuB{sub 2} and Ru{sub 2}B{sub 3} have been synthesized by mechanical alloying and high pressure sintering methods using ruthenium (Ru) and boron (B) powders as raw materials. The crystal structures of borides were characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM). The results shown that only RuB{sub 1.1} with hexagonal crystal structure was synthesized during the ball milling process, the orthorhombic RuB{sub 2} was synthesized under high pressure (5 GPa) and high temperature (1000 °C) conditions, while the hexagonal Ru{sub 2}B{sub 3} can be synthesized under 5 GPa and 1200 °C. The mechanism of synthesis for the ruthenium borides (RuB{sub x}) are discussed in details.

  14. Cartography/Geodesy Utilization Field and Geodetic Career Field (AFSs 57XX and 222X0).

    DTIC Science & Technology

    1984-01-01

    include the Geodetic Specialist, DAFSCs 22230, 22250, 22270 , 22290, and 22200. The occupational survey data were collected and analyzed to identify... 22270 , 22290, and 22200 were asked to complete a job inventory. Individuals filled out an identification and background information section and then...RESPONDING DAFSC DAFSC DAFSC 22230 22250 22270 INTERESTING 100 87 88 so-so - 11 6 DULL - 2 6 TABLE 23 AFSC 222X0 UTILIZATION OF TALENTS PERCENT RESPONDING

  15. A Critical Analysis of the U.S. Marine Corps 04XX Logistics Community

    DTIC Science & Technology

    2013-04-15

    CLEARA NCE REQUES T FOR PUBLIC RELEA SE OF DEPARTMENT OF DEFENSE INFORMAT ION (Soo fnsrrucTions on back.) (This form is To bo used in requesTing...J AN a()06 PREVIOUS EDIT ION M A Y BE USED. Reset Adobe Professicnol 8.0 1 3 - S - 2 100 Report Documentation Page Form ApprovedOMB No. 0704-0188...PERSON a. REPORT unclassified b. ABSTRACT unclassified c. THIS PAGE unclassified Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18

  16. Changing Security Threats: What Africans Must Accommodate in the XX1st Century.

    DTIC Science & Technology

    1999-03-30

    players are necessary to stem the tide of deterioration. An aggressive strategy towards improved socio-economic conditions in the short term and regional ... development in the long term is critical to ensure Sub-Saharan Africa becomes part of and play a participating role in the global economic community.

  17. Tips for a physician in getting the right job, Part XX: more comments on employment contracts.

    PubMed

    Harolds, Jay A

    2015-03-01

    This article discusses a variety of important employment contract issues. This includes remuneration, fringe benefits, and time off. It also includes dispute resolution and the protection of assets and information. Several types of restrictive covenants are also discussed. This information should be useful to job seekers attempting to understand contracts. However, all employment contracts should be discussed with the job seeker's attorney before signing it.

  18. Properties and nature of Be stars. XX. Binary nature and orbital elements of gamma Cas

    NASA Astrophysics Data System (ADS)

    Harmanec, P.; Habuda, P.; Štefl, S.; Hadrava, P.; Korčáková, D.; Koubský, P.; Krtička, J.; Kubát, J.; Škoda, P.; Šlechta, M.; Wolf, M.

    2000-12-01

    An analysis of accurate radial velocities (RVs) of the Be star gamma Cas from 295 Reticon spectrograms secured between October 1993 and May 2000 allowed us to prewhiten the RVs for the long-term changes and to obtain the first orbital RV curve of this star. The orbital period is 203 Delta59 and the orbit has an eccentricity of 0.26. The orbital motion is detectable even in the published velocities, based on photographic spectra. This implies that gamma Cas is a primary component of a spectroscopic binary. The secondary has a mass of about 1 \\ms, appropriate for a white dwarf or a neutron star, but it could also be a normal late-type dwarf. The ultimate solution of the dispute whether the observed X-ray emission is associated with the secondary or with the primary will need further dedicated studies.

  19. 77 FR 12089 - Proposed Generic Communication; Regulatory Issue Summary 2012-XX: Developing Inservice Testing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-28

    ... systems and components meet the requirements in the ASME OM Code and ASME B&PV Code, Section XI. These... NRC-2012-0048. NRC's Agencywide Documents Access and Management System (ADAMS): You may access... readiness of safety-related pumps and valves and inservice examinations of components and system...

  20. Changing Climate And Timberline Dynamics Of The Carpathians During XX Century

    NASA Astrophysics Data System (ADS)

    Martazinova, V.; Weisberg, P.; Maderych, V.; Ivanova, E.; Savchuk, S.; Shandra, A.

    2010-12-01

    In this investigation weather changes over the Carpathian Mountains during the 20th ct. and their influence on timberline changes are analyzed. Forest cover at timberline is ecologically and societally important because it decreases probability of avalanche occurrence, debris flows, and may decrease negative consequences of floods. First of all, changes in large-scale atmospheric circulation and the response of regional circulation over Carpathian territory were considered. Changes in temperature and precipitation were analyzed on a decadal basis for the 20th ct. and the first decade of the 21st ct. over three regions (West , East, and South Carpathians). The largest changes up to the 21st ct. are during the winter. In the West Carpathians, temperature has increased greatly during the winter, significantly less during the summer, and minimally during transitional seasons. Precipitation increased during the winter and summer, to a smaller extent in the fall, and decreased during spring. In the East Carpathians the increase of temperature is more pronounced in the winter and in the beginning of the 21st ct. exceeds mid-20th century by 1°C. Precipitation noticeably increased in the 1970’s and, until the beginning of the 21st ct., the South slope retained this level, whereas the North experienced an instability in precipitation. In the South Carpathians temperature at the beginning of the 21st ct. exceeds that of the mid-20th ct. by 1°C. The level of winter precipitation at the end of the last decade is similar to its level at the beginning of the study period, summer precipitation is less, and spring precipitation trends are geographically variable, risingon the South-western slopes and falling on the South-Eastern ones. Timberline changes between 1880 and 2000 were analyzed by comparing military maps of the Austro-Hungarian Empire and contemporary Landsat imagery. The whole region experienced a decline in forest cover from 73.2%, to 70.6%. Forest cover increased by nearly 7% in the West Carpathians by only 0,5% in the Ukrainian Carpathians, and decreased in the North and South Romanian Carpathians (-6,3% and -1,9%, respectively). Regional variation in forest cover change at timberline can be attributed to sociopolitical differences in land use practices over time, including logging, sheep and cattle pastures, and subsequent abandonment of pastures. A peak of afforestation occured at different elevations in the different regions, ranging from 1450 m to 1700 m. Most afforestation is associated with an expansion of coniferous, largely Picea-dominated forests, More than 50% of afforestation was associated with pasture abandonment, whereas 68% of deforestation was associated with human-caused pasture expansion. Deforestation exceeded afforestation at the highest timberline elevations, with the pattern reversed at lower elevations. Overall, the Carpathians timberline represents a complex mosaic of forests that have variously expanded and declined in extent and elevational range, highlighting the complex nature of mountain forest responses to climate change in the context of rapidly evolving land use practices.

  1. Low-cost/high-efficiency lasers for medical applications in the 14XX-nm regime

    NASA Astrophysics Data System (ADS)

    Callahan, J. J.; McIntyre, E.; Rafferty, C.; Yanushefski, L.; Bean, D. M.

    2011-03-01

    Laser therapy is becoming an increasingly popular method of treating numerous dermatological conditions. The widespread use of these devices is often limited by the cost and size. Low cost, portable lasers would expand the laser market further into homes, general practitioners, dermatologists, plastic surgeons, and 3rd world countries. There are numerous light devices currently on the market for hair removal and growth, acne reduction, and wrinkles. These devices are varied, from LEDs to intense pulsed light (IPL) to lasers. One particular disease is leishmaniasis, caused by a parasite carried by sand flies, most often occurring in third world countries. While there are drug therapies available, they sometimes require hospitalization for several days and are very expensive. An RF device has been FDA approved for treatment of leishmaniasis, but costs about $20,000 which is too expensive for widespread use. Since the method is heating the lesion, the same affect could be achieved using an infrared laser. Diode lasers have the capability to be produced in mass quantity for low costs, as shown by the ubiquity of diode lasers in the telecom industry and household appliances. Unfortunately, many diode lasers suffer from poor efficiency, particularly in wavelengths for dermatology. Advances are being made to improve wall plug efficiency of lasers to reduce waste heat and increase output power. In this paper, those efforts being made to develop manufacturing partners to lower the cost while increasing the production volume of long wavelength lasers will be discussed along with performance data and clinical results.

  2. 76 FR 54507 - Proposed Generic Communication; Draft NRC Generic Letter 2011-XX: Seismic Risk Evaluations for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-01

    ... seismic source and ground motion models provided by applicants. These seismic updates included new Electric Power Research Institute models to estimate earthquake ground motion and updated models for... earthquake-related data and models. These data and models suggest that the probability for earthquake...

  3. Case Study: Readiness and Total Ownership Cost Analyses for New Fighter Aircraft, F-XX

    DTIC Science & Technology

    2012-11-29

    held research fellowships at the University of Waterloo and the University of Cincinnati. He has worked for Shell Oil, Monsanto Corporation, and...its contacts in the Aerospace Industry Association (AIA) to reach out to like-minded individuals from multiple defense companies . These defense... company engineers were dedicated to rescuing the tarnished image of their profession by developing a design for an affordable, state-of-the-art

  4. 49 CFR 1242.35 - Repair and maintenance (account XX-26-41).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... shop repairs between these services on the basis of run-out unit miles of individual locomotive units...) Where the carrier maintains records of heavy shop repair costs by individual locomotive units or classes... locomotive units: (1) The heavy shop repairs shall be separated as indicated in paragraph (a) of this...

  5. Language XX: What shall it be called and why does it matter?

    PubMed

    Nelson, Nickola Wolf

    2016-06-01

    Terms suggested for unexpected language learning difficulty include specific language impairment, primary language disorder and language learning disability; however, none of them represents the critical element of literacy. Some experts have suggested that debating what to call language disorders is parallel to debating what to call reading disorders and dyslexia. In contrast, it is argued here that reading disorders are language disorders and not separate or parallel. Evidence is presented for quadrant models that explain language disorders and dyslexia along two dimensions-sound/word level (phonological) knowledge and sentence/discourse level (non-phonological) knowledge. Support for these two dimensions comes from factor analysis of a new assessment tool called the Test of Integrated Language and Literacy Skills (TILLS). Two case studies illustrate how a quadrant model can be used to explain patterns of abilities that vary along these two dimensions to parents and teachers. The article concludes with a recommendation to adopt a label that reflects language/literacy commonalities rather than differences, such as language/literacy disorder or specific language/literacy impairment.

  6. 15 CFR Appendix A to Chapter Xx - Administration of the Trade Agreements Program

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... authorized by the President or by the Special Representative. Sec. 5. Import Relief and Market Disruption. (a... quantitative restrictions proclaimed in order to provide import relief and is authorized to issue, under... Southeast Asia), and shall prepare, for the President's transmission to Congress, the reports and...

  7. 15 CFR Appendix A to Chapter Xx - Administration of the Trade Agreements Program

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... authorized by the President or by the Special Representative. Sec. 5. Import Relief and Market Disruption. (a... quantitative restrictions proclaimed in order to provide import relief and is authorized to issue, under... Southeast Asia), and shall prepare, for the President's transmission to Congress, the reports and...

  8. VizieR Online Data Catalog: Speckle interferometry at USNO. XX. (Hartkopf+, 2015)

    NASA Astrophysics Data System (ADS)

    Hartkopf, W. I.; Mason, B. D.

    2016-02-01

    This is the 20th in a series of papers from the U.S. Naval Observatory's speckle interferometry program, presenting results of observations obtained at the USNO 26inch telescope in Washington, DC. >From 2013 January 4 through 2014 December 18, the 26inch telescope was used on 135 of 451 scheduled nights. (6 data files).

  9. [Biennial Survey of Education, 1926-1928. Bulletin, 1930, No. 16. Chapter I - Chapter XX

    ERIC Educational Resources Information Center

    Office of Education, United States Department of the Interior, 1930

    1930-01-01

    This document contains the first twenty chapters of the Biennial Survey of Education document, covering the years 1926-1928. The following chapters are included in this document: (1) Higher education (Arthur J. Klein); (2) Medical education (N. P. Colwell); (3) Legal education (Alfred Z. Reed); (4) Significant movements in city school systems (W.…

  10. 76 FR 2924 - Proposed Generic Communications; Draft NRC Regulatory Issue Summary 2011-XX; Adequacy of Station...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-18

    ... regulatory requirements and voltage studies necessary for Degraded Voltage Relay (second level undervoltage... requirements and voltage studies necessary for Degraded Voltage Relay (second level undervoltage protection... Loss-of-Voltage Relays (LVRs) which are designed to detect loss of power to the bus from the...

  11. Follow-Up Study of 1990 Nursing Graduates. Volume XX, No. 10.

    ERIC Educational Resources Information Center

    Lucas, J.; Meltesen, C.

    In 1990, a follow-up study of nursing program graduates was conducted at William Rainey Harper College (WRHC) in Palatine, Illinois, to examine their employment patterns, further education plans, and evaluate particular aspects of their WRHC experience. All 98 nursing students who earned 48 credit hours in 1990 were mailed questionnaires 1 year…

  12. AUTOMOTIVE DIESEL MAINTENANCE 1. UNIT XX, CUMMINS DIESEL ENGINE, MAINTENANCE SUMMARY.

    ERIC Educational Resources Information Center

    Minnesota State Dept. of Education, St. Paul. Div. of Vocational and Technical Education.

    THIS MODULE OF A 30-MODULE COURSE IS DESIGNED TO PROVIDE A SUMMARY OF THE REASONS AND PROCEDURES FOR DIESEL ENGINE MAINTENANCE. TOPICS ARE WHAT ENGINE BREAK-IN MEANS, ENGINE BREAK-IN, TORQUING BEARINGS (TEMPLATE METHOD), AND THE NEED FOR MAINTENANCE. THE MODULE CONSISTS OF A SELF-INSTRUCTIONAL BRANCH PROGRAMED TRAINING FILM "CUMMINS DIESEL ENGINE…

  13. 49 CFR 1242.05 - Operating expense account number notation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., tools, supplies, fuels and lubricants (account 21-XX-XX); purchased services (accounts 31-XX-XX to 41-XX...: 11—Salaries and wages; 21—Materials, tools, supplies, fuels, and lubricants; 30 or...

  14. 49 CFR 1242.05 - Operating expense account number notation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., tools, supplies, fuels and lubricants (account 21-XX-XX); purchased services (accounts 31-XX-XX to 41-XX...: 11—Salaries and wages; 21—Materials, tools, supplies, fuels, and lubricants; 30 or...

  15. 49 CFR 1242.05 - Operating expense account number notation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., tools, supplies, fuels and lubricants (account 21-XX-XX); purchased services (accounts 31-XX-XX to 41-XX...: 11—Salaries and wages; 21—Materials, tools, supplies, fuels, and lubricants; 30 or...

  16. Time-Valued-Technology: A Light-Emitting Diode Case Study for Determining Replacement Strategy for High Technology Infrastructure Items

    DTIC Science & Technology

    2012-03-22

    STR_LWY_1S_XX_12_D_XX_XX_700 23652 272 86.96 STR_LWY_1S_XX_12_D_XX_XX_700_43k 21799 272 80.14 STR_LWY_2M_XX_12_D_XX_XX_700 20013 272 73.58...STR_LWY_3MP_XX_12_D_XX_XX_700_43K 15331 272 56.36 STR_LWY_4M_XX_12_D_XX_XX_700 20013 272 73.58 STR_LWY_4M_XX_12_D_XX_XX_700_43K 18445 272 67.81

  17. Radiation protection monitoring zone population NPP according to experts in case of emergency.

    PubMed

    Prilipko, V A; Shevchenko, K K

    2015-12-01

    Metoiu danogo doslidzhennia stala ekspertna otsinka realizatsiI zakhysnykh zakhodiv, spriamovanykh na obmezhennia op rominennia naselennia zony sposterezhennia atomnoI elektrostantsiI, na vypadok nadzvychaynoI sytuatsiI, z urakhu vanniam zakonodavchykh ta normatyvnykh dokumentiv.Metody. V protsesi doslidzhennia bulo zastosovano opytuvannia z vykorystanniam metodu ekspertnykh otsinok. Sformovano chotyry grupy fakhivtsiv, iaki nesut' vidpovidal'nist' za stan radiatsiynogo zakhystu riznykh grup nase lennia zony sposterezhennia Rivnens'koI atomnoI elektrostantsiI. Vymogamy vidboru buly: dosvid roboty za fa khom ne mensh nizh 10 rokiv, vidpovidnyy profil' ta posada. Dlia otrymannia pervynnykh empirychnykh danykh bulo zastosovano proste uporiadkuvannia znachen', Ikh parne chy poslidovne porivniannia.Rezul'taty. Za otsinkamy ekspertiv, zakhody opovishchennia, zabezpechenist' preparatamy stabil'nogo yodu, zabezpe chennia zasobiv kolektyvnogo (zakhysni sporudy, ukryttia) i indyvidual'nogo zakhystu (odiag, marlevi pov’iazky, respiratory, protyvogazy), material'no tekhnichnogo osnashchennia na vypadok nadzvychaynoI sytuatsiI na Rivnens'kiy atomniy elektrostantsiI suttievo vidrizniaiut'sia u sil's'kogo ta mis'kogo naselennia zony spostere zhennia. Grupoiu ryzyku, na vypadok nadzvychaynoI sytuatsiI, mozhut' staty uchni zagal'noosvitnikh shkil sil's'kykh te rytoriy zony sposterezhennia cherez nedoskonalist' systemy opovishchennia i vidsutnist' neobkhidnykh ob’iektiv ukryt tia. Ne isnuie odnostaynosti sered ekspertiv shchodo otsinok radiatsiynogo zakhystu riznykh grup naselennia zony spos terezhennia, zokrema zabezpechenosti zasobamy indyvidual'nogo i kolektyvnogo zakhystu, gotovnosti do zakhysnykh diy na vypadok nadzvychaynoI sytuatsiI.Vysnovky. Stan radiatsiynogo zakhystu naselennia zony sposterezhennia RAES, zokrema systema organizatsiynykh, tekhnichnykh, medyko biologichnykh, finansovo ekonomichnykh zakhodiv, shchodo zapobigannia ta reaguvannia na nadzvy chayni sytuatsi

  18. Experimental investigation of factors limiting slow axis beam quality in 9xx nm high power broad area diode lasers

    NASA Astrophysics Data System (ADS)

    Winterfeldt, M.; Crump, P.; Wenzel, H.; Erbert, G.; Tränkle, G.

    2014-08-01

    GaAs-based broad-area diode lasers are needed with improved lateral beam parameter product (BPPlat) at high power. An experimental study of the factors limiting BPPlat is therefore presented, using extreme double-asymmetric (EDAS) vertical structures emitting at 910 nm. Continuous wave, pulsed and polarization-resolved measurements are presented and compared to thermal simulation. The importance of thermal and packaging-induced effects is determined by comparing junction -up and -down devices. Process factors are clarified by comparing diodes with and without index-guiding trenches. We show that in all cases studied, BPPlat is limited by a non-thermal BPP ground-level and a thermal BPP, which depends linearly on self-heating. Measurements as a function of pulse width confirm that self-heating rather than bias-level dominates. Diodes without trenches show low BPP ground-level, and a thermal BPP which depends strongly on mounting, due to changes in the temperature profile. The additional lateral guiding in diodes with trenches strongly increases the BPP ground-level, but optically isolates the stripe from the device edges, suppressing the influence of the thermal profile, leading to a BPP-slope that is low and independent of mounting. Trenches are also shown to initiate strain fields that cause parasitic TM-polarized emission with large BPPlat, whose influence on total BPPlat remains small, provided the overall polarization purity is >95%.

  19. Dynamics of glass-forming liquids. XX. Third harmonic experiments of non-linear dielectric effects versus a phenomenological model

    NASA Astrophysics Data System (ADS)

    Kim, Pyeongeun; Young-Gonzales, Amanda R.; Richert, Ranko

    2016-08-01

    We have re-measured the third harmonic non-linear dielectric response of supercooled glycerol using zero-bias sinusoidal electric fields, with the aim of comparing the resulting susceptibilities with a phenomenological model of non-linear dielectric responses. In the absence of known chemical effects in this liquid, the present model accounts for three sources of non-linear behavior: dielectric saturation, field induced entropy reduction, and energy absorption from the time dependent field. Using parameters obtained from static high field results, the present model reproduces the characteristic features observed in the third harmonic susceptibility spectra: a low frequency plateau originating from dielectric saturation and a peak positioned below the loss peak frequency whose amplitude increases with decreasing temperature. Semi-quantitative agreement is achieved between experiment and the present model, which does not involve spatial scales or dynamical correlations explicitly. By calculating the three contributions separately, the model reveals that the entropy effect is the main source of the "hump" feature of this third harmonic response.

  20. Experimental investigation of factors limiting slow axis beam quality in 9xx nm high power broad area diode lasers

    SciTech Connect

    Winterfeldt, M. Crump, P.; Wenzel, H.; Erbert, G.; Tränkle, G.

    2014-08-14

    GaAs-based broad-area diode lasers are needed with improved lateral beam parameter product (BPP{sub lat}) at high power. An experimental study of the factors limiting BPP{sub lat} is therefore presented, using extreme double-asymmetric (EDAS) vertical structures emitting at 910 nm. Continuous wave, pulsed and polarization-resolved measurements are presented and compared to thermal simulation. The importance of thermal and packaging-induced effects is determined by comparing junction -up and -down devices. Process factors are clarified by comparing diodes with and without index-guiding trenches. We show that in all cases studied, BPP{sub lat} is limited by a non-thermal BPP ground-level and a thermal BPP, which depends linearly on self-heating. Measurements as a function of pulse width confirm that self-heating rather than bias-level dominates. Diodes without trenches show low BPP ground-level, and a thermal BPP which depends strongly on mounting, due to changes in the temperature profile. The additional lateral guiding in diodes with trenches strongly increases the BPP ground-level, but optically isolates the stripe from the device edges, suppressing the influence of the thermal profile, leading to a BPP-slope that is low and independent of mounting. Trenches are also shown to initiate strain fields that cause parasitic TM-polarized emission with large BPP{sub lat}, whose influence on total BPP{sub lat} remains small, provided the overall polarization purity is >95%.

  1. 75 FR 60756 - Information Collection; OMB Control No. 3090-00XX; Reporting and Use of Information Concerning...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-01

    ... report on terminations of awards due to material failure to comply with award terms and conditions; administrative agreements with entities to resolve suspension or debarment proceedings; and findings that... State award. As section 872 requires, an entity also would be able to submit comments to the data...

  2. Thermochemistry of organic, elementorganic and inorganic species. Part XX. Enthalpies of formation for free radicals of main group elements’ halogenides

    NASA Astrophysics Data System (ADS)

    Ponomarev, Dmitry; Takhistov, Viatcheslav; Slayden, Suzanne; Liebman, Joel

    2008-03-01

    General trends in thermochemistry for free radicals as the fragments of halogenated molecules of main group elements were found for the first time applying the series of isodesmic (working) reactions following the Benson's comparison of relative stabilities of free radicals in equations R+RH→ RH+R+Q, where Q is stabilization (destabilization) energy. The enthalpies of formation for parent molecules of main group elements' halogenides necessary for application of this and similar equations were presented earlier [A.V. Golovin, V.V. Takhistov, J. Mol. Struct., 784 (2006) 47.]. For fluorinated free radicals rad EF (E = Be-Ra), rad EF 2 ( rad EHF) (E = B-Tl, N-Bi) and rad EF 3 ( rad EH 2F, rad EHF 2) (E = C-Pb) the gradual decrease in stabilization by fluorine atoms was found when coming down the periodic table. This turned to destabilization for Tl, Sb, and Bi, and IVth group of elements (excluding carbon) with increasing destabilization in the row Si < Ge < Sn < Pb. The destabilization of free radicals by other halogens for IVth group of elements decreased in the row F > Cl > Br > I which was interpreted by involvement of polarizability (PAZ) effect of halogens increasing in this direction. For finding the enthalpies of formation for silicon and germanium-centered free radicals the data on ν ≡ E-H frequencies in IR-spectra were applied. Quite definite tendencies in structure/enthalpy of formation interrelationship were found for chlorinated, brominated and iodinated free radicals of IInd and IIIrd group of elements. In the VIth group the situation with F → Cl → Br → I replacement in stabilization of free radical center appeared completely different compared with II-IV groups. Owing to the high electronegativity of HO-group and low thermodynamic stability of HO rad radical all halogens highly stabilize rad OX radical and perform it in the row F < Cl-Br < I which is explained by increase of PAZ effect in this direction. All halogens are suggested to stabilize other rad EX free radicals (E = S-Po) but essentially less compared with rad OX free radicals. The tendencies in stabilization/destabilization for Vth group free radicals appeared to be intermediate between those for IVth and VIth groups.

  3. Planck intermediate results. XX. Comparison of polarized thermal emission from Galactic dust with simulations of MHD turbulence

    NASA Astrophysics Data System (ADS)

    Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Alina, D.; Alves, M. I. R.; Aniano, G.; Armitage-Caplan, C.; Arnaud, M.; Arzoumanian, D.; Ashdown, M.; Atrio-Barandela, F.; Aumont, J.; Baccigalupi, C.; Banday, A. J.; Barreiro, R. B.; Battaner, E.; Benabed, K.; Benoit-Lévy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Boulanger, F.; Bracco, A.; Burigana, C.; Cardoso, J.-F.; Catalano, A.; Chamballu, A.; Chiang, H. C.; Christensen, P. R.; Colombi, S.; Colombo, L. P. L.; Combet, C.; Couchot, F.; Coulais, A.; Crill, B. P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Dickinson, C.; Diego, J. M.; Donzelli, S.; Doré, O.; Douspis, M.; Dupac, X.; Efstathiou, G.; Enßlin, T. A.; Eriksen, H. K.; Falgarone, E.; Fanciullo, L.; Ferrière, K.; Finelli, F.; Forni, O.; Frailis, M.; Fraisse, A. A.; Franceschi, E.; Galeotta, S.; Ganga, K.; Ghosh, T.; Giard, M.; Giraud-Héraud, Y.; González-Nuevo, J.; Górski, K. M.; Gregorio, A.; Gruppuso, A.; Guillet, V.; Hansen, F. K.; Harrison, D. L.; Helou, G.; Hernández-Monteagudo, C.; Hildebrandt, S. R.; Hivon, E.; Hobson, M.; Holmes, W. A.; Hornstrup, A.; Huffenberger, K. M.; Jaffe, A. H.; Jaffe, T. R.; Jones, W. C.; Juvela, M.; Keihänen, E.; Keskitalo, R.; Kisner, T. S.; Kneissl, R.; Knoche, J.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lamarre, J.-M.; Lasenby, A.; Lawrence, C. R.; Leonardi, R.; Levrier, F.; Liguori, M.; Lilje, P. B.; Linden-Vørnle, M.; López-Caniego, M.; Lubin, P. M.; Macías-Pérez, J. F.; Maino, D.; Mandolesi, N.; Maris, M.; Marshall, D. J.; Martin, P. G.; Martínez-González, E.; Masi, S.; Matarrese, S.; Mazzotta, P.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Miville-Deschênes, M.-A.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Munshi, D.; Murphy, J. A.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C. B.; Noviello, F.; Novikov, D.; Novikov, I.; Oxborrow, C. A.; Pagano, L.; Pajot, F.; Paoletti, D.; Pasian, F.; Pelkonen, V.-M.; Perdereau, O.; Perotto, L.; Perrotta, F.; Piacentini, F.; Piat, M.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Popa, L.; Pratt, G. W.; Prunet, S.; Puget, J.-L.; Rachen, J. P.; Reinecke, M.; Remazeilles, M.; Renault, C.; Ricciardi, S.; Riller, T.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Roudier, G.; Rusholme, B.; Sandri, M.; Scott, D.; Soler, J. D.; Spencer, L. D.; Stolyarov, V.; Stompor, R.; Sudiwala, R.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J. A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Tucci, M.; Umana, G.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vielva, P.; Villa, F.; Wade, L. A.; Wandelt, B. D.; Zonca, A.

    2015-04-01

    Polarized emission observed by Planck HFI at 353 GHz towards a sample of nearby fields is presented, focusing on the statistics of polarization fractions p and angles ψ. The polarization fractions and column densities in these nearby fields are representative of the range of values obtained over the whole sky. We find that: (i) the largest polarization fractions are reached in the most diffuse fields; (ii) the maximum polarization fraction pmax decreases with column density NH in the more opaque fields with NH> 1021 cm-2; and (iii) the polarization fraction along a given line of sight is correlated with the local spatial coherence of the polarization angle. These observations are compared to polarized emission maps computed in simulations of anisotropic magnetohydrodynamical turbulence in which we assume a uniform intrinsic polarization fraction of the dust grains. We find that an estimate of this parameter may be recovered from the maximum polarization fraction pmax in diffuse regions where the magnetic field is ordered on large scales and perpendicular to the line of sight. This emphasizes the impact of anisotropies of the magnetic field on the emerging polarization signal. The decrease of the maximum polarization fraction with column density in nearby molecular clouds is well reproduced in the simulations, indicating that it is essentially due to the turbulent structure of the magnetic field: an accumulation of variously polarized structures along the line of sight leads to such an anti-correlation. In the simulations, polarization fractions are also found to anti-correlate with the angle dispersion function 𝒮. However, the dispersion of the polarization angle for a given polarization fraction is found to be larger in the simulations than in the observations, suggesting a shortcoming in the physical content of these numerical models. In summary, we find that the turbulent structure of the magnetic field is able to reproduce the main statistical properties of the dust polarization as observed in a variety of nearby clouds, dense cores excluded, and that the large-scale field orientation with respect to the line of sight plays a major role in the quantitative analysis of these statistical properties. Appendices are available in electronic form at http://www.aanda.org

  4. Grafting onto wool. XX. Graft copolymerization of vinyl monomers by use of redox initiators. Comparison of monomer reactivities

    SciTech Connect

    Misra, B.N.; Singha, A.S.; Sharma, R.K.

    1982-04-01

    Methyl methacrylate (MMA) and ethylacrylate (EA) have been graft copolymerized onto Himachali wool in aqueous medium by using a ferrous ammonium sulfate-hydrogen peroxide (FAS-H/sub 2/O/sub 2/) system as redox initiator. Percentage of grafting has been determined as functions of concentration of monomer, molar ratio of (FAS)/(H/sub 2/O/sub 2/), time, and temperature. Percentage of grafting is found to depend upon the molar ratio of (FAS)/(H/sub 2/O/sub 2/). An attempt has been made to compare the reactivities of the acceptor monomer (MMA and EA) with that of the donor monomer (VAc) toward grafting onto wool.

  5. Missing XX Chromosomes or Gender In/equity in Design and Technology Education? The Case of British Columbia.

    ERIC Educational Resources Information Center

    Braundy, Marcia; O'Riley, Pat; Petrina, Stephen; Dalley, Stephen; Paxton, Anabelle

    2000-01-01

    Presents data demonstrating the disproportionately low numbers of female technology teachers, teacher educators, and students in British Columbia. Discusses recruiting inequities, history of gendering in industrial technology classrooms, and resistance to gender-specific interventions. Outlines a technology education curriculum for all students.…

  6. History of the Astronomy in the Century XX: Perspective Cosmo-philosophically of its Advances and their Origenes

    NASA Astrophysics Data System (ADS)

    Fernandez Quintano, Jose

    The man has for the first time been able to contemplate from the Earth space. For the first time, a cosmological theory, the big-bang, physically explains the origin of the universe. But also, for the first time, the man has seen reunited the origins of this celestial science through the paleolithics antecedents, and just discovered in Mesopotamia. Now, the philosophy proposes through the thinking J. Habermas, an ideal community of speech. Now, astronomy proposes a model that explains the causal origins of all the created one. Of the assembly of recoveries, it excels the recovery of the old cuneiform cultures. Compared vision of assembly and between the assyriologists outstanding work like Epping, Strassmaier and Kugler, goes to der Waerden and Neugebauer, along with the work of eminent physicists and thinkers of this century.

  7. Selected Rapporteur Summaries from the XX World Congress of Psychiatric Genetics, Hamburg, Germany, October 14-18, 2012

    PubMed Central

    Anderson-Schmidt, Heike; Beltcheva, Olga; Brandon, Mariko D; Byrne, Enda M; Diehl, Eric J; Duncan, Laramie; Gonzalez, Suzanne D; Hannon, Eilis; Kantojärvi, Katri; Karagiannidis, Iordanis; Kos, Mark Z; Kotyuk, Eszter; Laufer, Benjamin I; Mantha, Katarzyna; McGregor, Nathaniel W; Meier, Sandra; Nieratschker, Vanessa; Spiers, Helen; Squassina, Alessio; Thakur, Geeta A; Tiwari, Yash; Viswanath, Biju; Way, Michael J; Wong, Cybele CP; O'Shea, Anne; DeLisi, Lynn E

    2014-01-01

    The XXth World Congress of Psychiatric Genetics (WCPG), sponsored by The International Society of Psychiatric Genetics (ISPG) took place in Hamburg, Germany on October 14-18, 2012. Approximately 600 participants gathered to discuss the latest findings in this rapidly advancing field. The following report was written by student travel awardees. Each was assigned sessions as rapporteurs. This manuscript represents topics covered in most, but not all, oral presentations during the conference, and some of the major notable new findings reported at this 2012 WCPG. PMID:23341144

  8. Experience and Perspectives of Art History Development in Educational Space of Siberia at the Turn of XX-XXI ?enturies

    ERIC Educational Resources Information Center

    Nekhvyadovich, Larisa Ivanovna; Chernyaeva, Irina Valerievna

    2016-01-01

    The article has a program-analytical nature, contains an analysis and assessment of the scientific school of T. M. Stepanskaya, Doctor of Arts, professor, member of Russian Union of Artists. The goal of T. M. Stepanskaya's professional activity is incorporation of Art History in higher educational institutions in Siberia. The authors consider the…

  9. El Material Suplementario En Los Diccionarios Bilingues Espanol-Ingles Mas Representativos De Los Siglos XX y XXI

    ERIC Educational Resources Information Center

    Fischer Dorantes, Erica

    2010-01-01

    This work is one of the first attempts to make a detailed and comparative analysis of the supplementary material of several bilingual English-Spanish dictionaries from the 20th and 21st centuries. It examines the historical development of prefaces and appendices in the most representative bilingual English-Spanish dictionaries that have…

  10. 75 FR 43166 - Information Collection; OMB Control No. 3090-00XX; FSRS Registration and Prime Awardee Entity...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-23

    ... regarding FSRS Registration and Prime Awardee Entity-Related Information Reporting Requirements. Public... performance of functions of the FSRS Registration and Prime Awardee Entity-Related Information Reporting... ``Information Collection 3090-XXXX, FSRS Registration and Prime Awardee Entity- Related Information ]...

  11. General trends in the change in solar activity indices in the period from the late XX to early XXI century

    NASA Astrophysics Data System (ADS)

    Bruevich, E. A.; Yakunina, G. V.

    2015-12-01

    We present an analysis of observations of the indices of the sunspot numbers (SSN from the National Oceanic and Atmospheric Administration (NOAA)), the radio-emission flux at a wavelength of 10.7 cm ( F 10.7), and the Total Solar Irradiance (TSI) in cycles 22-24. We have found that the ratio of the observed values SSNobs to the calculated ones SSNsyn (from the regression relations between SSN and F 10.7) decreases after 1990 by 20-25%, rather than by 35%, as was supposed earlier. The characteristics of the most widely used SSN index, such as the decrease in sunspot numbers and magnetic field strength in small and medium spots, do not change in complete correspondence to the expected scenario of the solar activity development predicted from the flux F 10.7 in cycles 23 and 24; they also cannot be fully explained by an additional minimum of the secular cycle. We also showed that the observed SSN changes lead to an increase of the Total Solar Irradiance in activity cycles 23-24 as compared to that in cycle 22.

  12. 39 CFR 3060.21 - Income report.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 20xx FY 20xx-1 Percent change fromSPLY Percent change fromSPLY Revenue: $x,xxx $x,xxx xxx xx.x (1) Mail and Services Revenues xxx xxx xx xx.x (2) Investment Income x,xx x,xxx xxx xx.x (3) Total Competitive Products Revenue Expenses: (4) Volume-Variable Costs x,xxx x,xxx xxx xx.x (5) Product Specific Costs...

  13. 39 CFR 3060.21 - Income report.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 20xx FY 20xx-1 Percent change fromSPLY Percent change fromSPLY Revenue: $x,xxx $x,xxx xxx xx.x (1) Mail and Services Revenues xxx xxx xx xx.x (2) Investment Income x,xx x,xxx xxx xx.x (3) Total Competitive Products Revenue Expenses: (4) Volume-Variable Costs x,xxx x,xxx xxx xx.x (5) Product Specific Costs...

  14. 39 CFR 3060.21 - Income report.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 20xx FY 20xx-1 Percent change fromSPLY Percent change fromSPLY Revenue: $x,xxx $x,xxx xxx xx.x (1) Mail and Services Revenues xxx xxx xx xx.x (2) Investment Income x,xx x,xxx xxx xx.x (3) Total Competitive Products Revenue Expenses: (4) Volume-Variable Costs x,xxx x,xxx xxx xx.x (5) Product Specific Costs...

  15. 39 CFR 3060.21 - Income report.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 20xx FY 20xx-1 Percent change fromSPLY Percent change fromSPLY Revenue: $x,xxx $x,xxx xxx xx.x (1) Mail and Services Revenues xxx xxx xx xx.x (2) Investment Income x,xx x,xxx xxx xx.x (3) Total Competitive Products Revenue Expenses: (4) Volume-Variable Costs x,xxx x,xxx xxx xx.x (5) Product Specific Costs...

  16. 39 CFR 3060.21 - Income report.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 20xx FY 20xx-1 Percent change fromSPLY Percent change fromSPLY Revenue: $x,xxx $x,xxx xxx xx.x (1) Mail and Services Revenues xxx xxx xx xx.x (2) Investment Income x,xx x,xxx xxx xx.x (3) Total Competitive Products Revenue Expenses: (4) Volume-Variable Costs x,xxx x,xxx xxx xx.x (5) Product Specific Costs...

  17. 48 CFR 752.7003 - Documentation for payment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... provides space to report by line item for products or services provided. The form provides for the.... vouchered to date Amt. vouchered this period 001 Product/Service Desc. for Line Item 001 $XXXX.XX $ XXXX.XX 002 Product/Service Desc. for Line Item 002 XXXX.XX XXXX.XX Total XXXX.XX XXXX.XX (2) The...

  18. Unique unbalanced X;X translocation (Xq22;p11.2) in a woman with primary amenorrhea but without Ullrich-Turner syndrome

    SciTech Connect

    Letterie, G.S.

    1995-12-04

    This is a report of a patient with delayed puberty and a previously unreported translocation 46,X,-X,+der(X),t(X;X) (q22;p11.2) without any manifestations of Ullrich-Turner syndrome. The relationship of this unbalanced translocation to the critical region hypothesis is discussed. 6 refs., 3 figs.

  19. [THE SCIENTIFIC REVOLUTION IN MEDICINE OF THE LAST QUARTER OF XIX-FIRST HALF OF XX CENTURIES. REPORT II. THE OUTSET OF REVISION OF MEDICAL SCIENCE].

    PubMed

    Stochik, A M; Zatravkin, S N

    2015-01-01

    The article affirms that onset of revision of picture of analyzed reality, methodological approaches to studying of vital activity of human organism and philosophical basics of medical science refers to 1878 and is related to publishing of "The course of general physiology" by French physiologist Claude Bernard. The implemented analysis of the text of this work permit to establish that C. Bernard undertook an attempt to introduce conception of human organism as a processing system being self-reproduced as. a result of interaction with environment due to mechanisms of self-regulation. The necessity was substantiated to make experiment the leading method of cognition of vital activity. The living wholeness (organism, cell) was proposed to be an object of experimentation. In this living wholeness its natural capacities to self-regulation of main vital processes can be preserved at its maximum. The new senses were introduced into ontological categories of thing, process, causality, portion and whole.

  20. Transiting exoplanets from the CoRoT space mission. XX. CoRoT-20b: A very high density, high eccentricity transiting giant planet

    NASA Astrophysics Data System (ADS)

    Deleuil, M.; Bonomo, A. S.; Ferraz-Mello, S.; Erikson, A.; Bouchy, F.; Havel, M.; Aigrain, S.; Almenara, J.-M.; Alonso, R.; Auvergne, M.; Baglin, A.; Barge, P.; Bordé, P.; Bruntt, H.; Cabrera, J.; Carpano, S.; Cavarroc, C.; Csizmadia, Sz.; Damiani, C.; Deeg, H. J.; Dvorak, R.; Fridlund, M.; Hébrard, G.; Gandolfi, D.; Gillon, M.; Guenther, E.; Guillot, T.; Hatzes, A.; Jorda, L.; Léger, A.; Lammer, H.; Mazeh, T.; Moutou, C.; Ollivier, M.; Ofir, A.; Parviainen, H.; Queloz, D.; Rauer, H.; Rodríguez, A.; Rouan, D.; Santerne, A.; Schneider, J.; Tal-Or, L.; Tingley, B.; Weingrill, J.; Wuchterl, G.

    2012-02-01

    We report the discovery by the CoRoT space mission of a new giant planet, CoRoT-20b. The planet has a mass of 4.24 ± 0.23 MJup and a radius of 0.84 ± 0.04 RJup. With a mean density of 8.87 ± 1.10 g cm-3, it is among the most compact planets known so far. Evolutionary models for the planet suggest a mass of heavy elements of the order of 800 M⊕ if embedded in a central core, requiring a revision either of the planet formation models or both planet evolution and structure models. We note however that smaller amounts of heavy elements are expected by more realistic models in which they are mixed throughout the envelope. The planet orbits a G-type star with an orbital period of 9.24 days and an eccentricity of 0.56.The star's projected rotational velocity is vsini = 4.5 ± 1.0 km s-1, corresponding to a spin period of 11.5 ± 3.1 days if its axis of rotation is perpendicular to the orbital plane. In the framework of Darwinian theories and neglecting stellar magnetic breaking, we calculate the tidal evolution of the system and show that CoRoT-20b is presently one of the very few Darwin-stable planets that is evolving toward a triple synchronous state with equality of the orbital, planetary and stellar spin periods. The CoRoT space mission, launched on December 27th 2006, has been developed and is operated by CNES, with the contribution of Austria, Belgium, Brazil, ESA (RSSD and Science Programme), Germany, and Spain.

  1. Photochemical Tissue Bonding for Military Medical Applications Practical Low Cost Low Damage Blood Vessel Repair: Albumin Stent Bonded With 19xx nm Laser

    DTIC Science & Technology

    2011-02-24

    applicable Federal regulations. The rabbits will be socialized to human contact one week prior to surgery with the use of hay and apples to make pre and...Animals will be observed for signs of abscess, fever , respiratory failure, and loss of appetite. The key to effective assessment of pain and efficacy of

  2. Unique unbalanced X;X translocation (Xq22;p11.2) in a woman with primary amenorrhea but without Ullrich-Turner syndrome.

    PubMed

    Letterie, G S

    1995-12-04

    This is a report of a patient with delayed puberty and a previously unreported translocation 46,X -X, +der(X),t(X;X) (q22;p11.2) without any manifestations of Ullrich-Turner syndrome. The relationship of this unbalanced translocation to the critical region hypothesis is discussed.

  3. 40 CFR Table 2 to Subpart Xx of... - Requirements of 40 CFR Part 61, Subpart FF, Not Included in the Requirements for This Subpart and...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) National Emission Standards for Ethylene Manufacturing Process Units: Heat Exchange Systems and Waste... annual benzene quatity for waste from your facility is * * * Do not comply with: Instead, comply with: 1. Less than 10 Mg/yr 40 CFR 61.340 § 63.1093. 40 CFR 61.342(c)(3)(ii), (d), and (e) There is...

  4. Water Quality Instructional Resources Information System (IRIS): A Compilation of Abstracts to Water Quality and Water Resources Materials, Supplement XX (1984).

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus, OH. Information Reference Center for Science, Mathematics, and Environmental Education.

    Compiled are abstracts and indexes to selected print and non-print materials related to wastewater treatment and water quality education and instruction, as well as materials related to pesticides, hazardous wastes, and public participation. Sources of abstracted/indexed materials include all levels of government, private concerns, and educational…

  5. CHROMATOGRAPHIC TECHNIQUES IN PHARMACEUTICAL ANALYSIS IN POIAND: HISTORY AND THE PRESENCE ON THE BASIS OF PAPERS PUBLISHED IN SELECTED POLISH PHARMACEUTICAL JOURNALS IN XX CENTURY.

    PubMed

    Bilek, Maciej; Namieśnik, Jacek

    2016-01-01

    For a long time, chromatographic techniques and techniques related to them have stimulated the development of new procedures in the field of pharmaceutical analysis. The newly developed methods, characterized by improved metrological parameters, allow for more accurate testing of, among others, the composition of raw materials, intermediates and final products. The chromatographic techniques also enable studies on waste generated in research laboratories and factories producing pharmaceuticals and parapharmaceuticals. Based on the review of reports published in Polish pharmaceutical journals, we assessed the impact of chromatographic techniques on the development of pharmaceutical analysis. The first chromatographic technique used in pharmaceutical analysis was a so-called capillary analysis. It was applied in the 1930s to control the identity of pharmaceutical formulations. In the 1940s and 1950s, the chromatographic techniques were mostly a subject of review publications, while their use in experimental work was rare. Paper chromatography and thin layer chromatography were introduced in the 1960s and 1970s, respectively. These new analytical tools have contributed to the intensive development of research in the field of phytochemistry and the analysis of herbal medicines. The development of colunm chromatography-based techniques, i.e., gas chromatography and high performance liquid chromatography took place in the end of 20th century. Both aforementioned techniques were widely applied in pharmaceutical analysis, for example, to assess the stability of drugs, test for impurities and degradation products as well as in pharmacokinetics studies. The first decade of 21" century was the time of new detection methods in gas and liquid chromatography. The information sources used to write this article were Polish pharmaceutical journals, both professional and scientific, originating from the interwar and post-war period, i.e., "Kronika Farmaceutyczna", "Farmacja Współczesna", "Wiadomości Farmaceutyczne", "Acta Poloniae Pharmaceutica", "Farmacja Polska", "Dissertationes Pharmaceuticae", "Annales UMCS sectio DDD Phamacia". The number of published works using various chromatography techniques was assessed based on the content description of individual issues of the journal "Acta Poloniae Pharmaceutica".

  6. Heat Capacity And Structural Relaxation In Se{sub 80-x}Te{sub 20}Ag{sub x}(x = 3 and 9) Glassy Alloys

    SciTech Connect

    Naqvi, S. Faheem; Saxena, N. S.

    2011-10-20

    This paper reports the effects of annealing time and temperature on the thermodynamics of enthalpy relaxation of Se{sub 80-x}Te{sub 20}Ag{sub x} (x = 3,9) glasses. Differential Scanning Calorimetry (DSC) method is optimized for the measurement of enthalpy relaxation in the vicinity of glass transition. The recovery of excess enthalpy ({Delta}H{sub excess}) has been calculated from the knowledge of excess specific heat ({Delta}C{sub p}). It is found that excess enthalpy released ({Delta}H{sub excess}) increase with increase in annealing time (t{sub a}). From the knowledge of excess specific heat ({Delta}C{sub p}) and {Delta}H{sub excess}, it has been found that sub-T{sub g} annealing of glass leads to decrease in enthalpy of the system and thereby taking it to the more equilibrium state.

  7. Mechanisms of mitochondrial holocytochrome c synthase and the key roles played by cysteines and histidine of the heme attachment site, Cys-XX-Cys-His.

    PubMed

    Babbitt, Shalon E; San Francisco, Brian; Mendez, Deanna L; Lukat-Rodgers, Gudrun S; Rodgers, Kenton R; Bretsnyder, Eric C; Kranz, Robert G

    2014-10-17

    Mitochondrial cytochrome c assembly requires the covalent attachment of heme by thioether bonds between heme vinyl groups and a conserved CXXCH motif of cytochrome c/c1. The enzyme holocytochrome c synthase (HCCS) binds heme and apocytochrome c substrate to catalyze this attachment, subsequently releasing holocytochrome c for proper folding to its native structure. We address mechanisms of assembly using a functional Escherichia coli recombinant system expressing human HCCS. Human cytochrome c variants with individual cysteine, histidine, double cysteine, and triple cysteine/histidine substitutions (of CXXCH) were co-purified with HCCS. Single and double mutants form a complex with HCCS but not the triple mutant. Resonance Raman and UV-visible spectroscopy support the proposal that heme puckering induced by both thioether bonds facilitate release of holocytochrome c from the complex. His-19 (of CXXCH) supplies the second axial ligand to heme in the complex, the first axial ligand was previously shown to be from HCCS residue His-154. Substitutions of His-19 in cytochrome c to seven other residues (Gly, Ala, Met, Arg, Lys, Cys, and Tyr) were used with various approaches to establish other roles played by His-19. Three roles for His-19 in HCCS-mediated assembly are suggested: (i) to provide the second axial ligand to the heme iron in preparation for covalent attachment; (ii) to spatially position the two cysteinyl sulfurs adjacent to the two heme vinyl groups for thioether formation; and (iii) to aid in release of the holocytochrome c from the HCCS active site. Only H19M is able to carry out these three roles, albeit at lower efficiencies than the natural His-19.

  8. Mechanisms of Mitochondrial Holocytochrome c Synthase and the Key Roles Played by Cysteines and Histidine of the Heme Attachment Site, Cys-XX-Cys-His*

    PubMed Central

    Babbitt, Shalon E.; San Francisco, Brian; Mendez, Deanna L.; Lukat-Rodgers, Gudrun S.; Rodgers, Kenton R.; Bretsnyder, Eric C.; Kranz, Robert G.

    2014-01-01

    Mitochondrial cytochrome c assembly requires the covalent attachment of heme by thioether bonds between heme vinyl groups and a conserved CXXCH motif of cytochrome c/c1. The enzyme holocytochrome c synthase (HCCS) binds heme and apocytochrome c substrate to catalyze this attachment, subsequently releasing holocytochrome c for proper folding to its native structure. We address mechanisms of assembly using a functional Escherichia coli recombinant system expressing human HCCS. Human cytochrome c variants with individual cysteine, histidine, double cysteine, and triple cysteine/histidine substitutions (of CXXCH) were co-purified with HCCS. Single and double mutants form a complex with HCCS but not the triple mutant. Resonance Raman and UV-visible spectroscopy support the proposal that heme puckering induced by both thioether bonds facilitate release of holocytochrome c from the complex. His-19 (of CXXCH) supplies the second axial ligand to heme in the complex, the first axial ligand was previously shown to be from HCCS residue His-154. Substitutions of His-19 in cytochrome c to seven other residues (Gly, Ala, Met, Arg, Lys, Cys, and Tyr) were used with various approaches to establish other roles played by His-19. Three roles for His-19 in HCCS-mediated assembly are suggested: (i) to provide the second axial ligand to the heme iron in preparation for covalent attachment; (ii) to spatially position the two cysteinyl sulfurs adjacent to the two heme vinyl groups for thioether formation; and (iii) to aid in release of the holocytochrome c from the HCCS active site. Only H19M is able to carry out these three roles, albeit at lower efficiencies than the natural His-19. PMID:25170082

  9. Implications for the North American Lower Crustal 7.xx km/s Layer from an Exhumed Crustal Root, Western Canadian Shield

    NASA Astrophysics Data System (ADS)

    Johnson, Calvin Everette, Jr.

    Lactic acid is widely existing in human bodies, animals and microorganisms. Recently, using biosensor to detect the concentration of lactic acid and diagnose disease have attracted great research and development interests. Nanocomposites is one of the best material used for biosensor because their wonderful conductivity, optical and electrochemical properties. In the study, MoS2 and polypyrrole (PPY) are used for the composite material electrode. To determine whether lactate oxidase (LOD) was helpful for the biosensor's detective properties, both PPY-MoS2 film with LOD and PPY-MoS2 film without LOD are being tested. The fourier transform infrared spectroscopy (FTIR) and Raman spectroscopic techniques have been used to understand the chemical bonds in the nanocomposite film. The X-ray diffraction (XRD) technique has been performed to understand the crystallographic structure of the MoS 2 -PPY film. The morphologies were confirmed by scanning electron microscopy (SEM). The UV-vis spectroscopy has been used to determine the band structure of composite film. Cyclic voltammetry (CV), chronoamperometry (CA), and electrochemical impedance spectroscopy (EIS) were used to analyze in different concentration of solution, under different scan rate to obtain stability and work efficiency. These results were compared with PPY-MoS2 film with and without lactate oxidase conditions. The chronoamperometric technique has been used to detect the concentration of lactic acid.

  10. Comparative anatomy of female genitalia of generic-level taxa in tribe Aedini (Diptera: Culicidae). Part XX. Genus Rampamyia Reinert, Harbach and Kitching.

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A comparative, morphological analysis of the female genitalia of the genus Rampamyia was conducted. The female genitalia of the genus are characterized and a comparison with other taxa is provided. The type species of the genus, Ra. notoscripta (Skuse), is illustrated. Treatment of the genital mo...

  11. Deletion 2q: two new cases with karyotypes 46,XY,del(2)(q31q33) and 46,XX,del(2)(q36).

    PubMed Central

    Young, R S; Shapiro, S D; Hansen, K L; Hine, L K; Rainosek, D E; Guerra, F A

    1983-01-01

    We describe the clinical and cytogenetic findings of two patients with deletions of the long arm of chromosome 2. One has an interstitial deletion identical to that found in a previously reported patient, although they are phenotypically dissimilar. The other patient has a terminal deletion, the first such deletion reported to date. Images PMID:6876110

  12. Chamber Tests with Human Subjects XX. Hypersensitivity to H as Demonstrated by Patch Tests Before and After Chamber Exposure to H Vapor

    DTIC Science & Technology

    1946-05-15

    intense erythema 4 a. erythema with edema b. dry scaling of scrotum c. maceration of axillary skin 5 a. vesicle b. numerous pinpoint vesicles c. crusting... skin reaction following exposure to H vapor in the man-chamber are discussed. Eight kodachrone prints, illustrating pertinent features, are included...Reactions for a Given Test Dose - 12 F. Changes in Threshold ------------------ 12 G. Abnormal Skin Reactions Following Chamber Exposures to H Vapor

  13. Detection of sex chromosomal aneuploidies X-X, Y-Y, and X-Y in human sperm using two-chromosome fluorescence in situ hybridization

    SciTech Connect

    Wyrobek, A.J.; Robbins, W.A. |; Pinkel, D.; Weier, H.U.; Mehraein, Y. |

    1994-10-15

    Sex chromosome aneuploidy is the most common numerical chromosomal abnormality in humans at birth and a substantial portion of these abnormalities involve paternal chromosomes. An efficient method is presented for using air-dried smears of human semen to detect the number of X and Y chromosomes in sperm chromatin using two-chromosome fluorescence in situ hybridization. Air-dried semen smears were pre-treated with dithiothreitol and 3,4-diiodosalicylate salt to decondense the sperm chromatin and then were hybridized with repetitive sequence DNA probes that had been generated by PCR and differentially labeled. Hybridizations with X and Y specific probes showed the expected ratio of 50%X:50%Y bearing sperm. Sperm carrying extra fluorescence domains representing disomy for the X or Y chromosomes occurred at frequencies of {approximately} 4 per 10,000 sperm each. Cells carrying both X and Y fluorescence domains occurred at a frequency of {approximately} 6/10,000. Thus, the overall frequency of sperm that carried an extra sex chromosome was 1.4/1,000. The frequencies of sperm carrying sex chromosome aneuploidies determined by hybridization did not differ statistically from those reported from the same laboratory using the human-sperm/hamster-egg cytogenetic technique. Multi-chromosome fluorescence in situ hybridization to sperm is a promising method for assessing sex-ratio alterations in human semen and for determining the fraction of sperm carrying sex or other chromosome aneuploidies which may be transmissible to offspring. 44 refs., 1 fig., 3 tabs.

  14. ASME N511-19XX, Standard for periodic in-service testing of nuclear air treatment, heating, ventilating and air conditioning systems

    SciTech Connect

    1997-08-01

    A draft version of the Standard is presented in this document. The Standard covers the requirements for periodic in-service testing of nuclear safety-related air treatment, heating, ventilating, and air conditioning systems in nuclear facilities. The Standard provides a basis for the development of test programs and does not include acceptance criteria, except in cases where the results of one test influence the performance of other tests. The Standard covers general inspection and test requirements, reference values, inspection and test requirements, generic tests, acceptance criteria, in-service test requirements, testing following an abnormal incident, corrective action requirements, and quality assurance. Mandatory appendices provide a visual inspection checklist and four test procedures. Non-mandatory appendices provide additional information and guidance on mounting frame pressure leak test procedure, corrective action, challenge gas substitute selection criteria, and test program development. 8 refs., 10 tabs.

  15. Effect of La surface treatments on corrosion resistance of A3 xx. x/SiC p composites in salt fog

    NASA Astrophysics Data System (ADS)

    Pardo, A.; Merino, M. C.; Arrabal, R.; Merino, S.; Viejo, F.; Coy, A. E.

    2006-02-01

    The influence of the SiC p proportion and the matrix concentration of four aluminium metal matrix composites (A360/SiC/10p, A360/SiC/20p, A380/SiC/10p, A380/SiC/20p) modified by lanthanum-based conversion or electrolysis coating was evaluated in neutral salt fog according to ASTM B 117. Lanthanum-based conversion coatings were obtained by immersion in 50 °C solution of La(III) salt and lanthanum electrolysis treatments were performed in ethylene glycol mono-butyl ether solution. These treatments preferentially covered cathodic areas such as intermetallic compounds, Si eutectic and SiC p. The kinetic of the corrosion process was studied on the basis of gravimetric tests. Both coating microstructure and nature of corrosion products were analyzed by scanning electron microscopy (SEM), atomic force microscopy (AFM), energy dispersive X-ray analysis (EDS) and low angle X-ray diffraction (XRD) before and after accelerated testing to determine the influence of microstructural changes on corrosion behaviour during exposure to the corrosive environment. The corrosion process was more influenced by the concentration of alloy elements in the matrix than by the proportion of SiC p reinforcement. Both conversion and electrolysis surface treatments improved the behaviour to salt fog corrosion in comparison with original composites without treatment. Additionally, electrolysis provided a higher degree of protection than the conversion treatment because the coating was more extensive.

  16. Female Teachers Training in Educational Grades of Women's Gymnasia in Kazan in the Last Third of the XIX--Early XX Centuries

    ERIC Educational Resources Information Center

    Kornilova, Irina V.; Magsumov, Timur A.; Shakirov, Rasul R.

    2016-01-01

    The purpose of the article is to study the way the female teacher education was formed in late imperial Russia. The subject of the study is the specific element of this process in Kazan province, being a multi-ethnic region. The article analyses a number of issues, the ones related to the activities of the two Kazan gymnasia--Maryinskaya and…

  17. Characterization of a 5.8-Mb interstitial deletion of chromosome 3p in a girl with 46,XX,inv(7)dn karyotype and phenotypic abnormalities.

    PubMed

    Morales, C; Mademont-Soler, I; Armengol, L; Milà, M; Badenas, C; Andrés, S; Soler, A; Sánchez, A

    2009-01-01

    Interstitial deletions of the short arm of chromosome 3 are rare, and a specific clinical phenotype has not been defined. We report the first isolated cryptic proximal interstitial 3p deletion, del(3)(p12.3p13), assessed by array-based comparative genomic hybridization in a girl with an inversion of chromosome 7, whose phenotype includes neurodevelopmental delay, growth retardation, dysmorphic facial features, hypophysis hypoplasia, gastroesophageal reflux, clinodactyly, preauricular appendix, and myopia. Her features are similar to those observed in the previously reported cases of proximal 3p deletions overlapping with our imbalance, indicating that her clinical manifestations are likely to be due to the deletion. As our patient's imbalance is the first non-cytogenetically visible proximal interstitial 3p deletion uncomplicated by other imbalances, its characterization has allowed us to narrow the minimal deletion interval associated with growth retardation and neurodevelopmental delay to the 3p12.3-p13 region. Among the genes found in this region, ROBO1, ROBO2, PDZRN3 and CNTN3 might play a role in the neurodevelopmental delay of the patient. This study provides additional evidence that cryptic imbalances anywhere along the genome can be found in patients with phenotypic abnormalities and a balanced chromosome rearrangement.

  18. The SAURON project - XX. The Spitzer [3.6] - [4.5] colour in early-type galaxies: colours, colour gradients and inverted scaling relations

    NASA Astrophysics Data System (ADS)

    Peletier, Reynier F.; Kutdemir, Elif; van der Wolk, Guido; Falcón-Barroso, Jesús; Bacon, Roland; Bureau, Martin; Cappellari, Michele; Davies, Roger L.; de Zeeuw, P. Tim; Emsellem, Eric; Krajnović, Davor; Kuntschner, Harald; McDermid, Richard M.; Sarzi, Marc; Scott, Nicholas; Shapiro, Kristen L.; van den Bosch, Remco C. E.; van de Ven, Glenn

    2012-01-01

    We investigate the [3.6]-[4.5] Spitzer-IRAC colour behaviour of the early-type galaxies of the SAURON survey, a representative sample of 48 nearby ellipticals and lenticulars. We investigate how this colour, which is unaffected by dust extinction, can be used to constrain the stellar populations in these galaxies. We find a tight relation between the [3.6]-[4.5] colour and effective velocity dispersion, a good mass indicator in early-type galaxies: ([3.6]-[4.5])e = (-0.109 ? 0.007)?+ (0.154 ? 0.016). Contrary to other colours in the optical and near-infrared, we find that the colours become bluer for larger galaxies. The relations are tighter when using the colour inside re (scatter 0.013 mag), rather than the much smaller re/8 aperture (scatter 0.023 mag), due to the presence of young populations in the central regions. We also obtain strong correlations between the [3.6]-[4.5] colour and three strong absorption lines (H?, Mgb and Fe 5015). Comparing our data with the models of Marigo et al., which show that more metal rich galaxies are bluer, we can explain our results in a way consistent with results from the optical, by stating that larger galaxies are more metal rich. The blueing is caused by a strong CO absorption band, whose line strength increases strongly with decreasing temperature and which covers a considerable fraction of the 4.5-?m filter. In galaxies that contain a compact radio source, the [3.6]-[4.5] colour is generally slightly redder (by 0.015 ? 0.007 mag using the re/8 aperture) than in the other galaxies, indicating small amounts of either hot dust, non-thermal emission, or young stars near the centre. We find that the large majority of the galaxies show redder colours with increasing radius. Removing the regions with evidence for young stellar populations (from the H? absorption line) and interpreting the colour gradients as metallicity gradients, we find that our galaxies are more metal poor going outwards. The radial [3.6]-[4.5] gradients correlate very well with the metallicity gradients derived from optical line indices. We do not find any correlation between the gradients and galaxy mass; at every mass, galaxies display a real range in metallicity gradients. Consistent with our previous work on line indices, we find a tight relation between local [3.6]-[4.5] colour and local escape velocity. The small scatter from galaxy to galaxy, although not negligible, shows that the amount and distribution of the dark matter relative to the visible light cannot be too different from galaxy to galaxy. Due to the lower sensitivity of the [3.6]-[4.5] colour to young stellar populations, this relation is more useful to infer the galaxy potential than the Mgb-vesc relation.

  19. Innovative Features of Comparative-Historical Research of European and Azerbaijani Cultural Heritage (Based on the Materials of British and Azerbaijani Literature of the XX Century)

    ERIC Educational Resources Information Center

    Eugster, Nicolas; Hasanov, Elnur L.

    2016-01-01

    The beginning of the twentieth century is characterized as a period of formation of literary prose in Azerbaijan literature, which reminds already formed a new type of British prose. These new development trends appeared in plot, content, style, the world of characters, artistic-philosophical thought as well as in narrative features. The genre of…

  20. Sexual Fate Change of XX Germ Cells Caused by the Deletion of SMAD4 and STRA8 Independent of Somatic Sex Reprogramming

    PubMed Central

    Wu, Quan; Fukuda, Kurumi; Kato, Yuzuru; Zhou, Zhi; Deng, Chu-Xia; Saga, Yumiko

    2016-01-01

    The differential programming of sperm and eggs in gonads is a fundamental topic in reproductive biology. Although the sexual fate of germ cells is believed to be determined by signaling factors from sexually differentiated somatic cells in fetal gonads, the molecular mechanism that determines germ cell fate is poorly understood. Herein, we show that mothers against decapentaplegic homolog 4 (SMAD4) in germ cells is required for female-type differentiation. Germ cells in Smad4-deficient ovaries respond to retinoic acid signaling but fail to undergo meiotic prophase I, which coincides with the weaker expression of genes required for follicular formation, indicating that SMAD4 signaling is essential for oocyte differentiation and meiotic progression. Intriguingly, germline-specific deletion of Smad4 in Stra8-null female germ cells resulted in the up-regulation of genes required for male gonocyte differentiation, including Nanos2 and PLZF, suggesting the initiation of male-type differentiation in ovaries. Moreover, our transcriptome analyses of mutant ovaries revealed that the sex change phenotype is achieved without global gene expression changes in somatic cells. Our results demonstrate that SMAD4 and STRA8 are essential factors that regulate the female fate of germ cells. PMID:27606421

  1. 49 CFR 1242.15 - Roadway, tunnels and subways, bridges and culverts, ties, rails, other track material, ballast...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 9 2013-10-01 2013-10-01 false Roadway, tunnels and subways, bridges and culverts, ties, rails, other track material, ballast, track laying and surfacing, and road property damaged (accounts XX-17-10 to XX-18-12 inclusive, 21-17-13 to 21-18-16 inclusive, XX-17-17, XX-18-17, XX-17-48, and XX-18-48). 1242.15 Section...

  2. 49 CFR 1242.15 - Roadway, tunnels and subways, bridges and culverts, ties, rails, other track material, ballast...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Roadway, tunnels and subways, bridges and culverts, ties, rails, other track material, ballast, track laying and surfacing, and road property damaged (accounts XX-17-10 to XX-18-12 inclusive, 21-17-13 to 21-18-16 inclusive, XX-17-17, XX-18-17, XX-17-48, and XX-18-48). 1242.15 Section...

  3. Great Lakes and St. Lawrence Seaway Navigation Season Extension. Volume 4. Appendixes D - F

    DTIC Science & Technology

    1979-08-01

    rapidly increasing prices for imported oil . Relevant to the present analysis is the fact that the season extension program will likely result in some...iron and steel and fuel oil products. The harbor is not substantially engaged in handling iron ore, coal, and grain commodities which would be...xx X X xX 6.Harrassment x X xx XX 7.Denlal of Mig.Access 8. Oiling -Direct Mort. x x X Xx X X .Animals Lost in Track xx xx X O.Loss of Nesting Hab. xx X

  4. Issues Affecting Internet Use in Afghanistan and Developing Countries in the Middle East

    DTIC Science & Technology

    2002-08-20

    Issues Affecting Internet Use in Afghanistan and Developing Countries in the Middle East Elham Ghashghai and Rosalind Lewis RAND issue papers explore...COVERED (FROM - TO) xx-xx-2002 to xx-xx-2002 4. TITLE AND SUBTITLE Issues Affecting Internet Use in Afghanistan and Developing Countries in the Middle

  5. Reengineering the Air Travel Process

    DTIC Science & Technology

    1999-04-01

    Thesis 3. DATES COVERED (FROM - TO) xx-xx-1999 to xx-xx-1999 4. TITLE AND SUBTITLE Reengineering the Air Travel Process Unclassified 5a. CONTRACT...RELEASE , 13. SUPPLEMENTARY NOTES 14. ABSTRACT Every year, Department of Defense (DOD) travelers make thousands of trips that include air transportation

  6. Politics, Doctrine, and the Airman

    DTIC Science & Technology

    1998-04-01

    1921 and General Mitchell’s First Provisional Brigade sunk the Ostfriesland with 2,000-pound bombs. 8 Politically , the success of Mitchell’s bombing......FROM - TO) xx-xx-1998 to xx-xx-1998 4. TITLE AND SUBTITLE Politics , Doctrine, and the Airman Unclassified 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c

  7. Medical Separation Among Careerists

    DTIC Science & Technology

    2013-03-01

    Ammunition6and6Explosive6Ordnance6Disposal Logistics+Combat+Element 01XX Personnel6&6Administration 02XX Intelligence 04XX Logistics 05XX Plans 06XX/25XX/40XX...INSIDE$US3DISEASE INVOL$DIS$( PARENTHOOD $OR$CUSTODY$OF$MIN TERM3SPECIAL$ENL$PROG$INITIAL$PERIOD$AC VOL$DIS$(ACC$COMM$OR$WARRANT33RES) DEATH$OUTSIDE$US...0.019% Other 0.018% Other 0.018% Other 0.018% Other 0.018% Other 0.018% Other 0.015% Other 0.015% 82 OTHER&CODES Separation VOL$DIS$( PARENTHOOD

  8. A Comprehensive Study of the Tocks Island Lake Project and Alternatives. Part D. Institutional Alternatives.

    DTIC Science & Technology

    1975-06-01

    historical and archeological sites 3. Minimize displacement of people and businesses C. Economic 1. Generate local employment opportunities 2. Generate local...IMPACTS OF DEAUTHORIZATION 1. Economic and Social Impacts of TILP Deauthorization XIX-22 2. Land Use Impacts of TILP Deauthorization XIX-28 3...Route 209 XX-lI 3. Facilities to be Provided XX-12 D. ECONOMIC AND SOCIAL IMPACTS XX-14 E. ENVIRONMENTAL IMPACTS XX-16 1. Additional Costs XX-16 2

  9. A Solar-pumped Fluorescence Model for Line-by-line Emission Intensities in the B-X, A-X, and X-X Band Systems of 12C14N

    NASA Astrophysics Data System (ADS)

    Paganini, L.; Mumma, M. J.

    2016-09-01

    We present a new quantitative model for detailed solar-pumped fluorescent emission of the main isotopologue of CN. The derived fluorescence efficiencies permit estimation and interpretation of ro-vibrational infrared line intensities of CN in exospheres exposed to solar (or stellar) radiation. Our g-factors are applicable to astronomical observations of CN extending from infrared to optical wavelengths, and we compare them with previous calculations in the literature. The new model enables extraction of rotational temperature, column abundance, and production rate from astronomical observations of CN in the inner coma of comets. Our model accounts for excitation and de-excitation of rotational levels in the ground vibrational state by collisions, solar excitation to the {A}2{{{\\Pi }}}{{i}} and {B}2{{{Σ }}}+ electronically excited states followed by cascade to ro-vibrational levels of {X}2{{{Σ }}}+, and direct solar infrared pumping of ro-vibrational levels in the {X}2{{{Σ }}}+ state. The model uses advanced solar spectra acquired at high spectral resolution at the relevant infrared and optical wavelengths and considers the heliocentric radial velocity of the comet (the Swings effect) when assessing the exciting solar flux for a given transition. We present model predictions for the variation of fluorescence rates with rotational temperature and heliocentric radial velocity. Furthermore, we test our fluorescence model by comparing predicted and measured line-by-line intensities for {X}2{{{Σ }}}+ (1-0) in comet C/2014 Q2 (Lovejoy), thereby identifying multiple emission lines observed at IR wavelengths.

  10. A Solar-Pumped Fluorescence Model for Line-By-Line Emission Intensities in the B-X, A-X, and X-X Band Systems of 12C14N

    NASA Technical Reports Server (NTRS)

    Paganini, L.; Mumma, M. J.

    2016-01-01

    We present a new quantitative model for detailed solar-pumped fluorescent emission of the main isotopologue of CN. The derived fluorescence efficiencies permit estimation and interpretation of ro-vibrational infrared line intensities of CN in exospheres exposed to solar (or stellar) radiation. Our g-factors are applicable to astronomical observations of CN extending from infrared to optical wavelengths, and we compare them with previous calculations in the literature. The new model enables extraction of rotational temperature, column abundance, and production rate from astronomical observations of CN in the inner coma of comets. Our model accounts for excitation and de-excitation of rotational levels in the ground vibrational state by collisions, solar excitation to the A(sup 2)Pi(sub I) and B(sup 2)Sum(sup +) electronically excited states followed by cascade to ro-vibrational levels of X(sup 2)Sum(sup +), and direct solar infrared pumping of ro-vibrational levels in the X(sup 2)Sum(sup +) state. The model uses advanced solar spectra acquired at high spectral resolution at the relevant infrared and optical wavelengths and considers the heliocentric radial velocity of the comet (the Swings effect) when assessing the exciting solar flux for a given transition. We present model predictions for the variation of fluorescence rates with rotational temperature and heliocentric radial velocity. Furthermore, we test our fluorescence model by comparing predicted and measured line-by-line intensities for X(sup 2)Sum(sup +) (1-0) in comet C/2014 Q2 (Lovejoy), thereby identifying multiple emission lines observed at IR wavelengths.

  11. Angelman Syndrome Caused by Chromosomal Rearrangements: A Case Report of 46,XX,+der(13)t(13;15)(q14.1;q12)mat,-15 with an Atypical Phenotype and Review of the Literature.

    PubMed

    Niida, Yo; Sato, Hitoshi; Ozaki, Mamoru; Itoh, Masatsune; Ikeno, Kanju; Takase, Etsuko

    2016-01-01

    Less than 1% of the cases with Angelman syndrome (AS) are caused by chromosomal rearrangements. This category of AS is not well defined and may manifest atypical phenotypes. Here, we report a girl with AS due to der(13)t(13;15)(q14.1;q12)mat. SNP array detected the precise deletion/duplication points and the parental origin of the 15q deletion. Multicolor FISH confirmed a balanced translocation t(13;15)(q14.1;q12) in her mother. Her facial appearance showed some features of dup(13)(pter→q14). Also, she lacked the most characteristic and unique behavioral symptoms of AS, i.e., frequent laughter, happy demeanor, and easy excitability. A review of the literature indicated that AS cases caused by chromosomal rearrangements can be classified into 2 major categories and 4 groups. The first category is paternal uniparental disomy 15, which is subdivided into isodisomy by de novo rob(15;15) and heterodisomy caused by paternal translocation. The second category is the deletion of the AS locus due to maternal reciprocal translocation, which is subdivided into 2 groups associated with partial monosomy by 3:1 segregation and partial trisomy by adjacent-2 segregation. Classification into these categories facilitates the understanding of the mechanisms of chromosomal rearrangements and helps in accurate diagnosis and genetic counseling of these rare forms of AS.

  12. Stereospecific ligands and their complexes. XX. Synthesis, characterization and antimicrobial activity of palladium(II) complexes with some alkyl esters of ethylenediamine-N,N‧-di-S,S-(2,2‧-dibenzyl)acetic acid

    NASA Astrophysics Data System (ADS)

    Dimitrijević, Dejana P.; Radić, Gordana P.; Jevtić, Verica V.; Mišić, Milena; Baskić, Dejan; Trifunović, Srećko R.

    2014-08-01

    Four new palladium(II) complexes of general formula [PdCl2(R2-S,S-eddba)] (R = ethyl, n-propyl, n-butyl and n-pentyl; S,S-eddba = ethylenediamine-N,N‧-di-S,S-(2,2‧-dibenzyl)acetate) have been synthesized and characterized by microanalysis, infrared, 1H and 13C NMR spectroscopy. In vitro antimicrobial activity for ligands L1-L4 general formula R2-S,S-eddba and complexes C1-C4 was investigated.

  13. A rare prenatal case with two de novo inversions and a translocation: 48, XX,t(9;12)(q32;p24.3), inv(11)(p15.1q25), inv(13)(q12.q22)

    SciTech Connect

    Harrison, B.; Balaban, L.; Eldred, C.

    1994-09-01

    Ultrasound examination of a para 1, gravida 2, 26 y.o. showed severe hydrocephalus and polyhydramnios. Amniocentesis was performed at 27 weeks. High resolution chromosome analysis revealed a karyotype with a 9;12 translocation, a pericentric inversion of chromosome 11, and a paracentric inversion of chromosome 13. Parental chromosome studies were normal. The mother was not on medication prior to her pregnancy and there was no known exposure to radiation. Delivery was at 34 weeks gestation. The phenotype consisted of micrognathia, low set ears, hypertelorism, and hydrodcephaly. Review of the literature revealed a single report with multiple de novo aberrations consisting of a 6;14 translocation and a deleted 7. This was diagnosed in the child of a woman with systemic lupus erythematous treated with azathioprine. These types of abnormalities have been known to be induced by chemical and radiation exposure. High resolution banding combined with molecular studies presently improve our ability to detect subtle structural aberrations.

  14. Life sciences and space research XXIII(2): Planetary biology and origins of life; Proceedings of the Topical Meeting and Workshops XX, XXI and XXIII of the 27th COSPAR Plenary Meeting, Espoo, Finland, July 18-29, 1988

    NASA Technical Reports Server (NTRS)

    Schwartz, A. W. (Editor); Dose, K. (Editor); Raup, D. M. (Editor); Klein, H. P. (Editor); Devincenzi, D. L. (Editor)

    1989-01-01

    This volume includes chapters on exobiology in space, chemical and early biochemical evolution, life without oxygen, potential for chemical evolution in the early environment of Mars, planetary protection issues and sample return missions, and the modulation of biological evolution by astrophysical phenomena. Papers are presented on the results of spaceflight missions, the action of some factors of space medium on the abiogenic synthesis of nucleotides, early peptidic enzymes, microbiology and biochemistry of the methanogenic archaeobacteria, and present-day biogeochemical activities of anaerobic bacteria and their relevance to future exobiological investigations. Consideration is also given to the development of the Alba Patera volcano on Mars, biological nitrogen fixation under primordial Martian partial pressures of dinitrogen, the planetary protection issues in advance of human exploration of Mars, and the difficulty with astronomical explanations of periodic mass extinctions.

  15. Tank Driving Commands Preferred by Armor Noncommissioned Officers

    DTIC Science & Technology

    1989-07-01

    MARCH SPEED CATCHUP SPEEDb EASE OUT Forward Turn TURN TO RT/LFT HARD RT/LFT XX Reverse Speed MOVE BACK QUICK STOP Reverse Turn BACK RT/LFT BACK TO RT/LFT...MOVE OUT TURN RT/LFT SLOW DOWN (REV) BACK UP HARD RT/LFT 75-84% HOLD SPEED SPEED UP TO XX NEUTRAL RT/LFT CATCHUP SPEED SLOW DOWN TO XX SPEED UP (REV) 65...TO XX GUIDE RIGHT/LEFT SLOW DOWN TO XX HALF RIGHT/LEFT HOLD SPEED AT XX HOLD SPEED CATCHUP SPEEDMARCH SPEED Reverse EASE BACK HOLD RIGHT/LEFTb. HOLD

  16. Good Security Practices for Electronic Commerce, Including Electronic Data Interchange

    DTIC Science & Technology

    1993-12-01

    FROM - TO) xx-xx-2002 to xx-xx-2002 4. TITLE AND SUBTITLE Good Security Practices for Electronic Commerce , Including Electronic Data Interchange...Report 12/1/1993 4. TITLE AND SUBTITLE Good Security Practices for Electronic Commerce , Including Electronic Data Interchange 5. FUNDING NUMBERS 6...Maximum 200 Words) Electronic commerce (EC) is the use of documents in electronic form, rather than paper, for carrying out functions of business or

  17. Health of Women after Wartime Deployments: Correlates of Risk for Selected Medical Conditions among Females after Initial and Repeat Deployments to Afghanistan and Iraq, Active Component, U.S. Armed Forces

    DTIC Science & Technology

    2012-07-01

    chronic bronchitis are not summarized in this report. Results are available upon request to the MSMR editorial office (con- tact information...Female infertility 628.xx Respiratory illnesses Chronic sinusitis 473.xx Chronic bronchitis 491.xx Asthma 493.xx MSMR Vol. 19 No. 7 July 2012Page...chronic and relapsing con- ditions may reflect routine periodic fol- low-ups or the continuation of long-term rehabilitative treatments for

  18. Building a Better Trojan Horse: Emerging Army Roles in Joint Urban Operations

    DTIC Science & Technology

    2001-01-01

    Building a Better Trojan Horse : Emerging Army Roles in Joint Urban Operations A Monograph by MAJ Christopher H. Beckert Infantry, U.S. Army School...xx-xx-2000 to xx-xx-2000 5a. CONTRACT NUMBER 5b. GRANT NUMBER 4. TITLE AND SUBTITLE Building a Better Trojan Horse : Emerging Army Roles in Joint...TELEPHONE NUMBER International Area Code Area Code Telephone Number 703 767-9007 DSN 427-9007 2 Abstract BUILDING A BETTER TROJAN HORSE : EMERGING ARMY

  19. Medical Services: Nutrition Standards and Education

    DTIC Science & Technology

    2001-06-15

    Army Regulation 40–25 BUMEDINST 10110.6 AFI 44-141 Medical Services Nutrition Standards and Education Headquarters Departments of the Army, Navy, and...YYYY) 15-06-2001 2. REPORT TYPE 3. DATES COVERED (FROM - TO) xx-xx-2001 to xx-xx-2001 4. TITLE AND SUBTITLE Nutrition Standards and Education...AFI 44–141 Nutrition Standards and Education This revision-- o Renames the recommended nutrient standards, changing the term from Military Recommended

  20. United States - Cuba Policy: Strategic Framework for Re-emergent Relations

    DTIC Science & Technology

    2003-04-07

    USAWC STRATEGY RESEARCH PROJECT United States – Cuba Policy: Strategic Framework For Re-emergent Relations by Allen J. Jamerson United States Air...COVERED (FROM - TO) xx-xx-2002 to xx-xx-2003 4. TITLE AND SUBTITLE United States - Cuba Policy: Strategic Framework for Re-emergent Relations ... UNITED STATES – CUBA POLICY: STRATEGIC FRAMEWORK FOR RE-EMERGENT RELATIONS .....1 HISTORICAL PERSPECTIVE

  1. GaSe Parametric Oscillator Pumped by Powerful Holmium Laser Near 3 Microns

    DTIC Science & Technology

    2007-11-02

    GaSe Parametric Oscillator Pumped by Powerful Holmium Laser near 3 Microns EOARD OPO Contract F61775-99...COVERED (FROM - TO) xx-xx-2001 to xx-xx-2001 4. TITLE AND SUBTITLE GaSe Parametric Oscillator Pumped by Powerful Holmium Laser near 3 Microns Unclassified... holmium laser near 3 microns with a goal of achieving an output energy from the OPO near the degenerate wavelength of 10 to 20mJ per pulse. 15. SUBJECT

  2. Bridging the Gap Between Warfighters and Industry: The Professional and Personal Development of the Acquisition Officer

    DTIC Science & Technology

    1998-06-01

    Advisors and instructors evaluate each student throughout the year to assess strengths and weaknesses. Psychological testing, such as the Myers - Briggs ...DOCUMENTATION PAGE 1. REPORT DATE (DD- MM-YYYY) 01-06-1998 2. REPORT TYPE Thesis 3. DATES COVERED (FROM - TO) xx-xx-1998 to xx-xx-1998 4. TITLE AND...this paper did not attempt to evaluate the effectiveness of organization and process reforms, literature and interviewees clearly indicate they are 5

  3. 75 FR 32719 - Acquisition Regulation: Agency Supplementary Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-09

    ... revision reads as follows: 970.5204-1 Counterintelligence. * * * * * COUNTERINTELLIGENCE (XXX 20XX.... * * * * * AGREEMENT REGARDING WORKPLACE SUBSTANCE ABUSE PROGRAMS AT DOE SITES (XXX 20XX) * * * * * (b) * * * DOE may... Programs at DOE sites. * * * * * WORKPLACE SUBSTANCE ABUSE PROGRAMS AT DOE SITES (XXX 20XX) * * * * *...

  4. 49 CFR 1242.60 - Locomotive fuel, electric power purchased/produced for motive power and servicing locomotives...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Locomotive fuel, electric power purchased/produced for motive power and servicing locomotives (accounts XX-51-67, XX-51-68 and XX-51-69). 1242.60 Section...-Transportation § 1242.60 Locomotive fuel, electric power purchased/produced for motive power and...

  5. 49 CFR 1242.60 - Locomotive fuel, electric power purchased/produced for motive power and servicing locomotives...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Locomotive fuel, electric power purchased/produced for motive power and servicing locomotives (accounts XX-51-67, XX-51-68 and XX-51-69). 1242.60 Section...-Transportation § 1242.60 Locomotive fuel, electric power purchased/produced for motive power and...

  6. 49 CFR 1242.60 - Locomotive fuel, electric power purchased/produced for motive power and servicing locomotives...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 9 2013-10-01 2013-10-01 false Locomotive fuel, electric power purchased/produced for motive power and servicing locomotives (accounts XX-51-67, XX-51-68 and XX-51-69). 1242.60 Section...-Transportation § 1242.60 Locomotive fuel, electric power purchased/produced for motive power and...

  7. 49 CFR 1242.60 - Locomotive fuel, electric power purchased/produced for motive power and servicing locomotives...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Locomotive fuel, electric power purchased/produced for motive power and servicing locomotives (accounts XX-51-67, XX-51-68 and XX-51-69). 1242.60 Section...-Transportation § 1242.60 Locomotive fuel, electric power purchased/produced for motive power and...

  8. 49 CFR 1242.60 - Locomotive fuel, electric power purchased/produced for motive power and servicing locomotives...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Locomotive fuel, electric power purchased/produced for motive power and servicing locomotives (accounts XX-51-67, XX-51-68 and XX-51-69). 1242.60 Section...-Transportation § 1242.60 Locomotive fuel, electric power purchased/produced for motive power and...

  9. Final Environmental Assessment, Family Camp Facility Buckey Air Force Base, Colorado

    DTIC Science & Technology

    2008-02-07

    tondaysacresdayacrelb XX NONO 11081.3 2000 13028.1207.2 −×=××× SOX: ( ) ( )yrtonlb tondaysacresdayacrelb XX SOSO 21087.3 2000 13028.1221.0...1105100029.51044 =××× VOC: ( ) ( )yrton lb tondaysSFdaylbGSF VOCVOC 85.102000 11051000198.01044 =××× NOX: ( ) ( )yrtonlb tondaysSFdaylbGSF XX NONO ...tondaysSFdaylbGSF XX NONO 9.101 2000 1105100086.11044 =××× SOX: ( ) ( )yrtonlb tondaysSFdaylbGSF XX SOSO 6.12 2000 1105100023.01044 =××× PM10

  10. Permanent Seismically Induced Displacement of Rock-Founded Structures Computed by the Newmark Program

    DTIC Science & Technology

    2009-02-01

    Mexico H1 45 XX-XX-11 Victoria, Mexico 6/9/1980 UNAMUCSD Cerro Prieto 77 309_vmcp_315a.dat 6.3 34 0.294 -0.587 19.9 -16.8 9.43 -7.77 26.7 11.3 6.86...15.78 90 12 Rock(a) Mexico H2 315 XX-XX-11 Victoria, Mexico 6/9/1980 UNAMUCSD Cerro Prieto 78 310_vmcp_0upa.dat 6.3 34 0.244 -0.304 12.1 -10.6 3.61...4.81 19.5 13.8 5.90 12.69 47 10 Rock(a) Mexico V UP XX-XX-11 Victoria, Mexico 6/9/1980 UNAMUCSD Cerro Prieto 28 79 311_bbsv_090a.dat 6.5 40 0.059 -0.056

  11. 18 CFR Appendix B to Subpart H of... - Appendix B to Subpart H of Part 35

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...-79XX-000 NA NA NA NA NA NA NA NA. RST LLC ER01-2XX5-000 Green CoGen WWW Corp RST LLC 5/23/2005 New York ISO Northeast 12/20/2003 2000 MW (nameplate). Sample Co. ER03-XX45-000 Sample Co. 3 Sample Co YYY Corp 2/1/1982 Sample Co. balancing authority Southwest 5/13/1973 10 MW (seasonal). *If an entity has...

  12. Air Force Integrated Readiness Measurement System (AFIRMS). Transform and Model Description.

    DTIC Science & Technology

    1985-09-30

    ing/ procesing etficiencies. -. ForecH---322- 3-19.- N D m 4 Dollars Tasked (Short) = (Quantity) X (Unit Price) W =l d= l M l R I here: Quantity...2727C. 29XX. 30X=. 3610C. 362X. 47X2 542XX. 545XX Civil Engineering 7 Ocer. 5516. 552.X OPE’ HQ AFESC/DEO RED HORSE onfl. 9346 Airma

  13. 40 CFR 86.1807-01 - Vehicle labeling.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Regulations Applicable to XXX-Fueled 20XX Model Year New Motor Vehicles.” (B) For light-duty trucks, the statement: “This Vehicle Conforms to U.S. EPA Regulations Applicable to XXX-Fueled 20XX Model Year New Light... Regulations Applicable to XXX-fueled 20XX Model Year New Medium-Duty Passenger Vehicles.” (D) For...

  14. 40 CFR 86.1807-01 - Vehicle labeling.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Regulations Applicable to XXX-Fueled 20XX Model Year New Motor Vehicles.” (B) For light-duty trucks, the statement: “This Vehicle Conforms to U.S. EPA Regulations Applicable to XXX-Fueled 20XX Model Year New Light... Regulations Applicable to XXX-fueled 20XX Model Year New Medium-Duty Passenger Vehicles.” (D) For...

  15. 40 CFR 86.1807-01 - Vehicle labeling.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Regulations Applicable to XXX-Fueled 20XX Model Year New Motor Vehicles.” (B) For light-duty trucks, the statement: “This Vehicle Conforms to U.S. EPA Regulations Applicable to XXX-Fueled 20XX Model Year New Light... Regulations Applicable to XXX-fueled 20XX Model Year New Medium-Duty Passenger Vehicles.” (D) For...

  16. 40 CFR 86.1807-01 - Vehicle labeling.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Regulations Applicable to XXX-Fueled 20XX Model Year New Motor Vehicles.” (B) For light-duty trucks, the statement: “This Vehicle Conforms to U.S. EPA Regulations Applicable to XXX-Fueled 20XX Model Year New Light... Regulations Applicable to XXX-fueled 20XX Model Year New Medium-Duty Passenger Vehicles.” (D) For...

  17. 40 CFR 86.1807-01 - Vehicle labeling.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Applicable to XXX-Fueled 20XX Model Year New Motor Vehicles.” (B) For light-duty trucks, the statement: “This Vehicle Conforms to U.S. EPA Regulations Applicable to XXX-Fueled 20XX Model Year New Light-Duty Trucks... Applicable to XXX-fueled 20XX Model Year New Medium-Duty Passenger Vehicles.” (D) For heavy-duty...

  18. Mosaicism for trisomy 3q arising from an unbalanced, de novo t(3;15).

    PubMed Central

    Stallings, R; Vaughn, D; Hall, K; Joyce, C; Ryan, F; Barton, D; Geraghty, M

    1997-01-01

    We report on a 2 1/2 year old girl who is dysmorphic, developmentally delayed, and mosaic for an unbalanced, de novo translocation between chromosomes 3 and 15. The karyotype from peripheral blood lymphocytes is 46,XX (50) and the karyotype from skin fibroblasts is 46,XX (28)/46,XX,der(15)t(3;15)(q11;p11) (23). The mechanism for the generation of this unbalanced, de novo translocation is discussed. Images PMID:9192276

  19. Planar Solid-Oxide Fuel Cell Research and Development

    DTIC Science & Technology

    2013-03-28

    Technical Report 3. DATES COVERED (From - To) 01/06/2010- 12/31/2012 4. TITLE AND SUBTITLE Planar Solid-Oxide Fuel Cell Research and Development...30-06-1998; xx-06-1998; xx-xx-1998. 2. REPORT TYPE. State the type of report , such as final, technical , interim, memorandum, master’s thesis... REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704-0188 The public reporting burden for this collection of information is estimated to average 1

  20. Dayton Aircraft Cabin Fire Model, Version 3. Volume II. Program User’s Guide and Appendices.

    DTIC Science & Technology

    1982-06-01

    ZDI. ZDJ. PUI.RUJ RLI,RLJ, * GUIJ. GUJI , GLIJ. GLJI) C C C OBJECTIVE: C (1) SUBROUTINE VENT COMPUTES THE RATES OF MASS FLOW THRU A SINGLE C VENT...THAT OF J C C GUJI - FLOW RATE FROM THE UPPER ZONE OF COMPARTMENT J TO THAT OF I C C GLIJ *-FLOW RATE FROM TH LOWER ZONE OF COMPARTMENT I TO THAT OF J...XX GO TO 120 112 OUI4 - GUIJ + XX GO TO 120 114 IF( ZL(K) QT. ZDJ ) 0O TO 116 GLJI a GLJI + XX GO TO 120 11b GUJI - GUJI + XX 120 CONTINUE C C

  1. Cry Havoc and Let Slip the Dogs of War

    DTIC Science & Technology

    2001-01-01

    service at the outbreak of the war. Furthermore, the Brits killed over 400,000 dogs and cats in London for fear of the expected German bombing. Sadly...CRY HAVOC AND LET SLIP THE DOGS OF WAR” SPECIAL OPERATIONS FORCES AND THE MILITARY WORKING DOG BY Major Joseph F. Whelan U.S. Army Special Forces...TO) xx-xx-2000 to xx-xx-2001 5a. CONTRACT NUMBER 5b. GRANT NUMBER 4. TITLE AND SUBTITLE ?CRY HAVOC AND LET SLIP THE DOGS OF WAR? Unclassified 5c

  2. A Comparative Pharmacokinetic Study of the Role of Gender and Developmental Differences in Occupational and Environmental Exposure to Benzene

    DTIC Science & Technology

    1994-09-01

    as follows: R = (Ci - Ce)/Ci x 100 where Ci = benzene concentration in inhaled air; Ce = benzene concentration in exhaled breath. Retention was...equation provided by Fisher et al. (1993:13) which scales an empirical VMAXC value to a specified body weight. VMAx = VMAxc x (Body Weight) exp .74 The...metabolism (VMAX). These results are expected since the ability of benzene to partition from the 4-2 PARAMETER AUCV AM Q_ XXX xx QC xx QL - X XX QS - x QR xx

  3. Readiness and Retention: Effects of Downsizing and Increased Operations Tempo

    DTIC Science & Technology

    1999-04-01

    AU/ACSC/120/1999-04 AIR COMMAND AND STAFF COLLEGE AIR UNIVERSITY READINESS AND RETENTION: EFFECTS OF DOWNSIZING AND INCREASED OPERATIONS TEMPO by...1999 2. REPORT TYPE Thesis 3. DATES COVERED (FROM - TO) xx-xx-1999 to xx-xx-1999 4. TITLE AND SUBTITLE Readiness and Retention: Effects of Downsizing ...to reduce defense spending created a period of downsizing . Since 1989 the U.S. Air Force has reduced its force by one-third and experienced 12 years of

  4. 40 CFR 63.1083 - Does this subpart apply to my heat exchange system?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Ethylene Manufacturing Process Units: Heat Exchange... or operate an ethylene production unit expressly referenced to this subpart XX from subpart YY...

  5. 40 CFR 63.1093 - Does this subpart apply to my waste streams?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... (CONTINUED) National Emission Standards for Ethylene Manufacturing Process Units: Heat Exchange Systems and... ethylene production facility expressly referenced to this subpart XX from subpart YY of this part....

  6. 40 CFR 63.1093 - Does this subpart apply to my waste streams?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (CONTINUED) National Emission Standards for Ethylene Manufacturing Process Units: Heat Exchange Systems and... ethylene production facility expressly referenced to this subpart XX from subpart YY of this part....

  7. 40 CFR 63.1093 - Does this subpart apply to my waste streams?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... (CONTINUED) National Emission Standards for Ethylene Manufacturing Process Units: Heat Exchange Systems and... ethylene production facility expressly referenced to this subpart XX from subpart YY of this part....

  8. 40 CFR 63.1083 - Does this subpart apply to my heat exchange system?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Ethylene Manufacturing Process Units: Heat Exchange... or operate an ethylene production unit expressly referenced to this subpart XX from subpart YY...

  9. 40 CFR 63.1093 - Does this subpart apply to my waste streams?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) National Emission Standards for Ethylene Manufacturing Process Units: Heat Exchange Systems and... ethylene production facility expressly referenced to this subpart XX from subpart YY of this part....

  10. 40 CFR 63.1083 - Does this subpart apply to my heat exchange system?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Ethylene Manufacturing Process Units: Heat Exchange... or operate an ethylene production unit expressly referenced to this subpart XX from subpart YY...

  11. 40 CFR 63.1093 - Does this subpart apply to my waste streams?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) National Emission Standards for Ethylene Manufacturing Process Units: Heat Exchange Systems and... ethylene production facility expressly referenced to this subpart XX from subpart YY of this part....

  12. 40 CFR 63.1083 - Does this subpart apply to my heat exchange system?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Ethylene Manufacturing Process Units: Heat Exchange... or operate an ethylene production unit expressly referenced to this subpart XX from subpart YY...

  13. 40 CFR 63.1083 - Does this subpart apply to my heat exchange system?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... CATEGORIES (CONTINUED) National Emission Standards for Ethylene Manufacturing Process Units: Heat Exchange... or operate an ethylene production unit expressly referenced to this subpart XX from subpart YY...

  14. Interactive Simulated Robot Construction and Controller Evolution

    DTIC Science & Technology

    2012-07-09

    Cooper. Predicting protein structures with a multiplayer online game . Nature, 466:756–760, 2010. [2] G. S. Hornby. Alps: the age-layered population...3] and framsticks[4] are available to the general public. The Foldit[1] online Permission to make digital or hard copies of all or part of this work...prior specific permission and/or a fee. GECCO 2012 Philadelphia, PA USA Copyright 20XX ACM X-XXXXX-XX-X/XX/XX ...$10.00. game has been successful in

  15. O Passado como Nacao: Imagens do Imperio nas Falas Reacionarias dos Anos 30 e 40 do Seculo XX: Uma Pequena Arqueologia do Debate Publico e Privado (The Past as Nation: Images of the Empire in the Reactionary Words of the 30s and 40s in the 20th Century: A Small Archaeology of the Public Debate versus the Private One).

    ERIC Educational Resources Information Center

    de Freitas, Marcos Cezar

    1998-01-01

    Suggests an archaeology of the public debate versus the private one in Brazil through analysis of the reactionary speech of a religious leader, Dom Jose Mauricio da Rocha, which produced innumerable representations of the Brazilian Empire. (PA)

  16. Les Differences dans l'emploi de la construction possessive "N1"+"DE"+"N2" entre le XIX et le XX s. dans la prose litteraire francaise (Differences in the Use of the Possessive Construction "N1"+"de"+"N2" between 19th and 20th Century French Literature).

    ERIC Educational Resources Information Center

    Roglic, Vera

    1991-01-01

    Study looks at frequency of noun1 + de + noun2 possessive in French prose. Researchers used chi-square and Pearson test to analyze results of syntagmatic possessive construction in works by Hugo, Stendahl, Balzac, Zola, Gide, Malraux, St. Exupery, and Sartre. Findings indicate that syntagmatic genitive possessive is more commonly found in…

  17. 76 FR 69294 - Proposed Generic Communication Draft Generic Letter on Seismic Risk Evaluations for Operating...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-08

    ... COMMISSION Proposed Generic Communication Draft Generic Letter on Seismic Risk Evaluations for Operating... public comment Draft Generic Letter 2011-XX: Seismic Risk Evaluations for Operating Reactors. The public... for public comment Draft Generic Letter 2011-XX: Seismic Risk Evaluations for Operating Reactors...

  18. 76 FR 18467 - Pennsylvania Regulatory Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-04

    ...), (ww), (xx), (zz), (aaa), (ccc), (iii), (jjj), (nnn), (ppp), and (ttt). It was also intended to address... mentioned above--30 CFR 938.16(rr) (tt), (uu), (vv), (ww), (xx), (zz), and (aaa); and (2) one required...)(2)(ii) to correct the cross-reference to section 86.63 with a reference to section 86.212(c)....

  19. 33 CFR 183.25 - Display of markings.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... XX Persons or XXX Pounds XXX Pounds, persons, motor, gear XXX Horsepower, motor or U.S. Coast Guard Maximum Capacities XX Persons or XXX Pounds XXX Pounds, persons, motor, gear XXX Horsepower, motor with remote steering XXX Horsepower, motor without remote steering (2) For inboard boats and...

  20. 33 CFR 183.25 - Display of markings.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... XX Persons or XXX Pounds XXX Pounds, persons, motor, gear XXX Horsepower, motor or U.S. Coast Guard Maximum Capacities XX Persons or XXX Pounds XXX Pounds, persons, motor, gear XXX Horsepower, motor with remote steering XXX Horsepower, motor without remote steering (2) For inboard boats and...

  1. 33 CFR 183.25 - Display of markings.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... XX Persons or XXX Pounds XXX Pounds, persons, motor, gear XXX Horsepower, motor or U.S. Coast Guard Maximum Capacities XX Persons or XXX Pounds XXX Pounds, persons, motor, gear XXX Horsepower, motor with remote steering XXX Horsepower, motor without remote steering (2) For inboard boats and...

  2. 33 CFR 183.25 - Display of markings.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... XX Persons or XXX Pounds XXX Pounds, persons, motor, gear XXX Horsepower, motor or U.S. Coast Guard Maximum Capacities XX Persons or XXX Pounds XXX Pounds, persons, motor, gear XXX Horsepower, motor with remote steering XXX Horsepower, motor without remote steering (2) For inboard boats and...

  3. 16 CFR Appendix A to Part 306 - Summary of Labeling Requirements for Biodiesel Fuels

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... required Either “B-XX Biodiesel Blend” or “Biodiesel Blend” contains biomass-based diesel or biodiesel in quantities between 5 percent and 20 percent Blue Biomass-Based Diesel No label required Either “XX% Biomass-Based Diesel Blend” or “Biomass-Based Diesel Blend” contains biomass-based diesel or biodiesel...

  4. 16 CFR Appendix A to Part 306 - Summary of Labeling Requirements for Biodiesel Fuels

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... required Either “B-XX Biodiesel Blend” or “Biodiesel Blend” contains biomass-based diesel or biodiesel in quantities between 5 percent and 20 percent Blue Biomass-Based Diesel No label required Either “XX% Biomass-Based Diesel Blend” or “Biomass-Based Diesel Blend” contains biomass-based diesel or biodiesel...

  5. 16 CFR Appendix A to Part 306 - Summary of Labeling Requirements for Biodiesel Fuels

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... required Either “B-XX Biodiesel Blend” or “Biodiesel Blend” contains biomass-based diesel or biodiesel in quantities between 5 percent and 20 percent Blue Biomass-Based Diesel No label required Either “XX% Biomass-Based Diesel Blend” or “Biomass-Based Diesel Blend” contains biomass-based diesel or biodiesel...

  6. 16 CFR Appendix A to Part 306 - Summary of Labeling Requirements for Biodiesel Fuels

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... required Either “B-XX Biodiesel Blend” or “Biodiesel Blend” contains biomass-based diesel or biodiesel in quantities between 5 percent and 20 percent Blue Biomass-Based Diesel No label required Either “XX% Biomass-Based Diesel Blend” or “Biomass-Based Diesel Blend” contains biomass-based diesel or biodiesel...

  7. 16 CFR Appendix A to Part 306 - Summary of Labeling Requirements for Biodiesel Fuels

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... required Either “B-XX Biodiesel Blend” or “Biodiesel Blend” contains biomass-based diesel or biodiesel in quantities between 5 percent and 20 percent Blue Biomass-Based Diesel No label required Either “XX% Biomass-Based Diesel Blend” or “Biomass-Based Diesel Blend” contains biomass-based diesel or biodiesel...

  8. 60 FR 47196 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Federal Register 2010, 2011, 2012, 2013, 2014

    1995-09-11

    ... SuperMAX Rules September 1, 1995. Pursuant to Section 19(b)(1) of the Securities Exchange Act of 1934..., proposes to amend Rule 37(e) of Article XX, relating to its Enhanced SuperMAX Program. II. Self-Regulatory... SuperMAX Program into CHX Article XX, Rule 37(e). The purpose of this proposed change is to...

  9. 60 FR 39465 - Self-Regulatory Organizations; Notice of Filing and Order Granting Accelerated Approval of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    1995-08-02

    ... Versions of the SuperMAX System on a Pilot Basis July 27, 1995. Pursuant to Section 19(b)(1) of the... subsection (e) and subsection (f) to Rule 37 of Article XX relating to the CHX's MAX System. The text of the proposed rule is as follows : Article XX Rule 37 (e) The Exchange's Enhanced SuperMAX program shall be...

  10. New Techniques for Absolute Gravity Measurements.

    DTIC Science & Technology

    1983-01-07

    Hammond, J.A. (1978) Bollettino Di Geofisica Teorica ed Applicata Vol. XX. 8. Hammond, J. A., and Iliff, R. L. (1979) The AFGL absolute gravity system...International Gravimetric Bureau, No. L:I-43. 7. Hammond. J.A. (1978) Bollettino Di Geofisica Teorica ed Applicata Vol. XX. 8. Hammond, J.A., and

  11. 49 CFR 1242.27 - Coal marine terminals, ore marine terminals, TOFC/COFC terminals, other marine terminals, motor...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    .../COFC terminals, other marine terminals, motor vehicle loading and distribution facilities, and facilities for other specialized service operations (accounts XX-13-29 to XX-13-35, inclusive). 1242.27..., motor vehicle loading and distribution facilities, and facilities for other specialized...

  12. 49 CFR 1242.44 - Trucks, trailers, and containers (revenue service) and floating equipment (revenue service...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) and floating equipment (revenue service) (accounts XX-23-43 and XX-23-44). 1242.44 Section 1242.44... BETWEEN FREIGHT SERVICE AND PASSENGER SERVICE FOR RAILROADS 1 Operating Expenses-Equipment § 1242.44 Trucks, trailers, and containers (revenue service) and floating equipment (revenue service) (accounts...

  13. Computer Program for Design and Performance Analysis of Navigation-Aid Power Systems. Program Documentation, Volume 1. Software Requirements Document

    DTIC Science & Technology

    1977-07-01

    Solar Cell I - V Curve...Calculate Solar Cell I - V Curve Correction Factor ROCELL ■ F (ROE, SUNLIT) at XX Where: ROCELL ■ Solar Cell I - V Curve Correction Factor at Solar...Insolation Level: XX ROE ■ Internal Table of Solar Cell I - V Curve Correction j Factor as a Function of Solar Insolation SUNLIT ■ Internal Table of

  14. 78 FR 71033 - Pipeline Safety: Information Collection Activities, Revisions to Incident and Annual Reports for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-27

    ... Other Gas Transmission and Gathering Pipeline Systems; PHMSA F 7100.3 Incident Report--Liquefied Natural Gas Facilities; and PHMSA F 7100.3-1 Annual Report for Calendar Year 20xx Liquefied Natural Gas... Calendar Year 20xx for Distribution Operators; PHMSA F 7100.2 Incident Report-- Natural and Other...

  15. Comments on the California Community Colleges' Plan for Allocating Board Financial Assistance to Community College Students: A Report to the Fiscal and Educational Policy Committees of the Legislature.

    ERIC Educational Resources Information Center

    California State Postsecondary Education Commission, Sacramento.

    In January 1984, the California State Legislature adopted Assembly Bill (AB) 1XX, which included provisions for a mandatory student fee and an appropriation for financial aid to offset that fee. This report by the California Postsecondary Education Commission (CPEC) describes the provisions of AB 1XX and the community college financial aid plan,…

  16. Muslim Culture: Center of Gravity for Global War on Terror

    DTIC Science & Technology

    2007-05-10

    The Middle East for Dummies , p. 59. xx Lewis, The Crisis of Islam, p. XX. xxi Pipes, Militant Islam Reaches America, p. 4. xxii Ibid., p. 28...Declaration of the War Against The Americans Occupying the Land of the Two Holy Places.” NWC 6023, 1996. Davis, Craig S. The Middle East for Dummies . Hoboken

  17. 49 CFR 1242.85 - Fringe benefits (account 12-63-00).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Fringe benefits (account 12-63-00). 1242.85....85 Fringe benefits (account 12-63-00). Separate the common expenses in proportion to the total common salaries and wages expense separation (account 11-XX-XX) determined in §§ 1242.83 and 1242.84....

  18. 49 CFR 1242.85 - Fringe benefits (account 12-63-00).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Fringe benefits (account 12-63-00). 1242.85....85 Fringe benefits (account 12-63-00). Separate the common expenses in proportion to the total common salaries and wages expense separation (account 11-XX-XX) determined in §§ 1242.83 and 1242.84....

  19. 49 CFR 1242.85 - Fringe benefits (account 12-63-00).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Fringe benefits (account 12-63-00). 1242.85....85 Fringe benefits (account 12-63-00). Separate the common expenses in proportion to the total common salaries and wages expense separation (account 11-XX-XX) determined in §§ 1242.83 and 1242.84....

  20. 49 CFR 1242.85 - Fringe benefits (account 12-63-00).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Fringe benefits (account 12-63-00). 1242.85....85 Fringe benefits (account 12-63-00). Separate the common expenses in proportion to the total common salaries and wages expense separation (account 11-XX-XX) determined in §§ 1242.83 and 1242.84....

  1. Evaluating the Epidemiology of Inflicted Traumatic Brain Injury in Infants of U.S. Military Families

    DTIC Science & Technology

    2008-01-01

    subdural hematoma and whiplash injuries. Caffey3 in 1972 theorized that shaking was responsible for retinal hemorrhages and subdural or subarachnoid...and contusion 852.xx Subarachnoid, subdural , and extradural hemorrhage after injury 853.xx Other and unspecified intracranial hemorrhage following

  2. Endangered Species on U.S. Army Installations.

    DTIC Science & Technology

    1982-08-01

    DESERT (9UNORA) x SALAMANDER, SACRAMENTO, *40LINTAIA XX HEDGEHOG CACTUS, KUENZLER XX PRICKLY-P(JPPY, x 48141 el veso tx BAT, FREE-TAILED, BRAZILIAN X SAT...aARRACKSp -4EDGEHOG CACTUS, KUENZLER PLANTS ENDANGERED FT. BLISS EDYOTIS ELATIOR VAR. ELATIOP PLANTS UNDLTERMINFO SCHOFIELD BARRACKS, 58 tLnYOTI

  3. Site characterization and hazard assessment criteria for natural phenomena hazards at DOE sites

    SciTech Connect

    Chen, J.C.; Lu, S.C.; Ueng, T.S.; Boissonnade, A.C.

    1993-09-01

    This paper briefly summarizes requirements for site characterization and hazard assessment of Natural Phenomena Hazards for compliance with DOE Order 5480.28. The site characterization criteria for NPH evaluation are provided in a draft DOE-STD-1022-XX and the assessment criteria of natural phenomena hazards are provided in draft DOE-STD-1023-XX.

  4. Trisomy 15 mosaicism and uniparental disomy (UPD) in a liveborn infant

    SciTech Connect

    Milunsky, J.M.; Wyandt, H.E.; Milunsky, A.

    1996-01-22

    We describe a liveborn infant with uniparental disomy (UPD) with trisomy 15 mosaicism. Third trimester amniocentesis yielded a 46,XX/47,XX,+15 karyotype. Symmetrical growth retardation, distinct craniofacies, congenital heart disease, severe hypotonia and minor skeletal anomalies were noted. The infant died at 6 weeks of life. Peripheral lymphocyte chromosomes were {open_quotes}normal{close_quotes} 46,XX in 100 cells. Parental lymphocyte chromosomes were normal. Skin biopsy showed 47,XX,+15 in 80% of fibroblasts and results were equivalent in fibroblasts from autopsy lung tissue. Molecular analysis revealed maternal uniparental heterodisomy for chromosome 15 in the 46,XX cell line. We describe an emerging phenotype of trisomy 15 mosaicism, confirm that more than one tissue should be studied in all cases of suspected mosaicism, and suggest that UPD be considered in all such cases. 19 refs., 2 figs., 1 tab.

  5. Meiotic germ cells antagonize mesonephric cell migration and testis cord formation in mouse gonads

    PubMed Central

    Yao, Humphrey H.-C.; DiNapoli, Leo; Capel, Blanche

    2014-01-01

    Summary The developmental fate of primordial germ cells in the mammalian gonad depends on their environment. In the XY gonad, Sry induces a cascade of molecular and cellular events leading to the organization of testis cords. Germ cells are sequestered inside testis cords by 12.5 dpc where they arrest in mitosis. If the testis pathway is not initiated, germ cells spontaneously enter meiosis by 13.5 dpc, and the gonad follows the ovarian fate. We have previously shown that some testis-specific events, such as mesonephric cell migration, can be experimentally induced into XX gonads prior to 12.5 dpc. However, after that time, XX gonads are resistant to the induction of cell migration. In current experiments, we provide evidence that this effect is dependent on XX germ cells rather than on XX somatic cells. We show that, although mesonephric cell migration cannot be induced into normal XX gonads at 14.5 dpc, it can be induced into XX gonads depleted of germ cells. We also show that when 14.5 dpc XX somatic cells are recombined with XY somatic cells, testis cord structures form normally; however, when XX germ cells are recombined with XY somatic cells, cord structures are disrupted. Sandwich culture experiments suggest that the inhibitory effect of XX germ cells is mediated through short-range interactions rather than through a long-range diffusible factor. The developmental stage at which XX germ cells show a disruptive effect on the male pathway is the stage at which meiosis is normally initiated, based on the immunodetection of meiotic markers. We suggest that at the stage when germ cells commit to meiosis, they reinforce ovarian fate by antagonizing the testis pathway. PMID:14561636

  6. Characterization of gonadal transcriptomes from Nile tilapia (Oreochromis niloticus) reveals differentially expressed genes.

    PubMed

    Tao, Wenjing; Yuan, Jing; Zhou, Linyan; Sun, Lina; Sun, Yunlv; Yang, Shijie; Li, Minghui; Zeng, Sheng; Huang, Baofeng; Wang, Deshou

    2013-01-01

    Four pairs of XX and XY gonads from Nile tilapia were sequenced at four developmental stages, 5, 30, 90, and 180 days after hatching (dah) using Illumina Hiseq(TM) technology. This produced 28 Gb sequences, which were mapped to 21,334 genes. Of these, 259 genes were found to be specifically expressed in XY gonads, and 69 were found to be specific to XX gonads. Totally, 187 XX- and 1,358 XY-enhanced genes were identified, and 2,978 genes were found to be co-expressed in XX and XY gonads. Almost all steroidogenic enzymes, including cyp19a1a, were up-regulated in XX gonads at 5 dah; but in XY gonads these enzymes, including cyp11b2, were significantly up-regulated at 90 dah, indicating that, at a time critical to sex determination, the XX fish produced estrogen and the XY fish did not produce androgens. The most pronounced expression of steroidogenic enzyme genes was observed at 30 and 90 dah for XX and XY gonads, corresponding to the initiation of germ cell meiosis in the female and male gonads, respectively. Both estrogen and androgen receptors were found to be expressed in XX gonads, but only estrogen receptors were expressed in XY gonads at 5 dah. This could explain why exogenous steroid treatment induced XX and XY sex reversal. The XX-enhanced expression of cyp19a1a and cyp19a1b at all stages suggests an important role for estrogen in female sex determination and maintenance of phenotypic sex. This work is the largest collection of gonadal transcriptome data in tilapia and lays the foundation for future studies into the molecular mechanisms of sex determination and maintenance of phenotypic sex in non-model teleosts.

  7. X-Chromosome Dosage and the Response to Cerebral Ischemia

    PubMed Central

    Turtzo, L. Christine; Siegel, Chad; McCullough, Louise D.

    2011-01-01

    Gonadal hormones contribute to ischemic neuroprotection, but cannot fully explain the observed sexual dimorphism in stroke outcomes seen during life stages with low sex steroid hormones. Sex chromosomal complement (XX in females; XY in males) may also contribute to ischemic sexual dimorphism. A transient middle cerebral artery occlusion model was used to investigate the role of X chromosome dosage in female XX and XO littermates of two mouse strains (Paf and EdaTa). Cohorts of XX and XO gonadally intact, ovariectomized, and ovariectomized females supplemented with estrogen were examined. Infarct sizes were equivalent between ovariectomized XX and XO mice, between intact XX and XO mice, and between estrogen-supplemented ovariectomized XX and XO mice. This is the first study to investigate the role of sex chromosome dosage in the response to cerebral ischemia. Neither the number of X chromosomes, nor the parent of origin of the remaining X chromosome, had a significant effect on the degree of cerebral infarction after experimental stroke in adult female mice. Estrogen was protective against cerebral ischemia in both XX and XO mice. PMID:21917808

  8. Reauthorization of the Adolescent Family Life Demonstration Projects Act of 1981. Hearings before the Subcommittee on Family and Human Services of the Committee on Labor and Human Resources. United States Senate, Ninety-Eighth Congress, Second Session on an Overview of the Adolescent Pregnancy Problem and Reauthorization of Title XX of the Public Health Service Act: The Adolescent Family Life Demonstration Projects Act of 1981 (April 24 and 26, 1984).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Committee on Labor and Human Resources.

    This document provides witness testimony and prepared statements from two Congressional hearings called to consider the reauthorization of the Adolescent Family Life Demonstration Projects. Testimony is presented from two officials of the Department of Health and Human Services who are responsible for administering the law, representatives from…

  9. Analysis of a Data Communication Network’s Performance under Varying Retransmission Disciplines

    DTIC Science & Technology

    1990-09-01

    SB1 EVE\\NT,5,i; ACT,,XX(5) .EQ. O,QBI; ACT,, ,DMP2; SB2 EVENT,5,1; ACT,,XX(5) .EQ. O,Q32; A CT .. ,DM P2; 5i33 EVENTr,5,1; ACT,,XX(5) .EQ. O, QB3 ; ACT...DMi2; QBI QUEUE( 23) ... ,NTHB; QB2 QUEUE(24),,,,TlI3; Q33 QUEUE( 25) ... 57 HTHB MATCH,6,QB1/NB1,QB2/NBi, QB3 /NB1; NB1 ACCU$%,,3,3,HIGH(9

  10. Construction of stable explicit finite-difference schemes for Schroedinger type differential equations

    NASA Technical Reports Server (NTRS)

    Mickens, Ronald E.

    1989-01-01

    A family of conditionally stable, forward Euler finite difference equations can be constructed for the simplest equation of Schroedinger type, namely u sub t - iu sub xx. Generalization of this result to physically realistic Schroedinger type equations is presented.

  11. Metrologia: uno sguardo alle grandezze fisiche fondamentali; il Pendolo, il Piano Inclinato e g

    NASA Astrophysics Data System (ADS)

    Sigismondi, Costantino

    2016-07-01

    Metrology studies the standards utilized in physics, we focus on MKS introduced by Giovanni Giorgi at the turn of XIX-XX century. Galileo, the pendulum and the inclined plane are reviewed to obtain the universal g.

  12. 75 FR 35442 - Fisheries of the Gulf of Mexico; Southeast Data, Assessment, and Review (SEDAR) Update; Greater...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-22

    ... National Oceanic and Atmospheric Administration RIN 0648-XX02 Fisheries of the Gulf of Mexico; Southeast Data, Assessment, and Review (SEDAR) Update; Greater Amberjack. AGENCY: National Marine Fisheries... and Gulf States Marine Fisheries Commissions have implemented the Southeast Data, Assessment...

  13. 75 FR 47266 - Fisheries of the South Atlantic; Southeast Data, Assessment, and Review (SEDAR); South Atlantic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-05

    ... National Oceanic and Atmospheric Administration RIN: 0648-XX60 Fisheries of the South Atlantic; Southeast Data, Assessment, and Review (SEDAR); South Atlantic red snapper AGENCY: National Marine Fisheries... Fisheries Southeast Regional Office and Southeast Fisheries Science Center. Participants include...

  14. 25 CFR 23.22 - Purpose of tribal government grants.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... contributing to family stability; (4) Home improvement programs with the primary emphasis on preventing the...-Federal matching shares in connection with funds provided under titles IV-B, IV-E and XX of the...

  15. 26 CFR 1.42-9 - For use by the general public.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Department of Housing and Urban Development (HUD) (24 CFR subtitle A and chapters I through XX). See HUD... social organization or provided by an employer for its employees, the unit is not for use by the...

  16. 26 CFR 1.42-9 - For use by the general public.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Department of Housing and Urban Development (HUD) (24 CFR subtitle A and chapters I through XX). See HUD... social organization or provided by an employer for its employees, the unit is not for use by the...

  17. MX Siting Investigation. Geotechnical Evaluation. Verification Study - Ralston Valley, Nevada. Volume II. Geotechnical Data.

    DTIC Science & Technology

    1980-06-15

    Table II-1-1 Explanation Station Number Geologic stations are numbered sequentially. Where more than one geologic field team worked in a CDP , stations...x xx J X x x X X xxL 0® XX x X 0 Sx x 00 x x j 0 x x x x e e -80 x x 0® Ixa® xx 0 a -200 0200 400 Boo Boo DISTANCE IN FEET 0 ESE SHOT F G H I...457 M SEC) sx 2020 FT SEC (616 M SEC) S 4000 FT SEC (1219 M SEC) S cW- 940 FT SEC ( 287 M SEE) oo 0 GM 1280 FT SEC (390 M SEC, 10 2460 FT SEC (750

  18. 75 FR 21385 - Applications of Atlas Air, Inc. for Certificate Authority

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-23

    ... Transportation. ACTION: Notice of Order to Show Cause (Order 2010-X-X), Dockets DOT- OST-2009-0267 and DOT-OST... Attachment A to the order. FOR FURTHER INFORMATION CONTACT: Mr. Scott Faulk, Air Carrier Fitness Division...

  19. 75 FR 57275 - Information Collection; Supplier Greenhouse Gas Emissions Inventory Pilot

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-20

    ... ADMINISTRATION Information Collection; Supplier Greenhouse Gas Emissions Inventory Pilot AGENCY: Federal... Supplier Greenhouse Gas (GHG) Emissions Inventory pilot. Public comments are particularly invited on... Information Collection 3090- 00XX; Supplier Greenhouse Gas Emissions Inventory Pilot, by any of the...

  20. 75 FR 39665 - Marine Mammals; File No. 14791

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration RIN 0648-XX38 Marine Mammals; File No. 14791 AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric Administration (NOAA),...

  1. 75 FR 40776 - Marine Mammals; File No. 14097

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-14

    ... National Oceanic and Atmospheric Administration RIN 0648-XX47 Marine Mammals; File No. 14097 AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric Administration (NOAA), Commerce. ACTION: Notice; issuance of permit. SUMMARY: Notice is hereby given that National Marine...

  2. Evolution of the linear-polarization-angle-dependence of the radiation-induced magnetoresistance-oscillations with microwave power

    SciTech Connect

    Ye, Tianyu; Mani, R. G.; Wegscheider, W.

    2014-11-10

    We examine the role of the microwave power in the linear polarization angle dependence of the microwave radiation induced magnetoresistance oscillations observed in the high mobility GaAs/AlGaAs two dimensional electron system. The diagonal resistance R{sub xx} was measured at the fixed magnetic fields of the photo-excited oscillatory extrema of R{sub xx} as a function of both the microwave power, P, and the linear polarization angle, θ. Color contour plots of such measurements demonstrate the evolution of the lineshape of R{sub xx} versus θ with increasing microwave power. We report that the non-linear power dependence of the amplitude of the radiation-induced magnetoresistance oscillations distorts the cosine-square relation between R{sub xx} and θ at high power.

  3. Resistance scaling for composite fermions in the presence of a density gradient.

    SciTech Connect

    Stormer, H. L.; Tsui, Daniel Chee; Pan, Wei; West, Ken W.; Baldwin, K. W.; Pfeiffer, Loren N.

    2006-02-01

    The magnetoresistance, R{sub xx}, at even-denominator fractional fillings, of an ultra high quality two-dimensional electron system at T {approx} 35 mK is observed to be strictly linear in magnetic field, B. While at 35 mK R{sub xx} is dominated by the integer and fractional quantum Hall states, at T {approx_equal} 1.2 K an almost perfect linear relationship between R{sub xx} and B emerges over the whole magnetic field range except for spikes at the integer quantum Hall states. This linear R{sub xx} cannot be understood within the Composite Fermion model, but can be explained through the existence of a density gradient in our sample.

  4. 49 CFR 1242.76 - Administration; pickup and delivery, marine line haul, and rail substitute service; loading...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... lost or damaged-solely related; fringe benefits; casualties and insurance; joint facility, and other... related; fringe benefits; casualties and insurance; joint facility, and other (accounts XX-34-01,...

  5. 40 CFR 52.224 - General requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... County APCD. (xvi) Shasta County APCD. (xvii) Sacramento County APCD. (xviii)-(xix) (xx) Lake County APCD...) (xxvi) San Luis Obispo County APCD. (xxvii) Kings County APCD. (xxviii) Plumas County APCD....

  6. A Method For The Longitudinal Study Of Behavioral Development In Infants And Children: The Early Development Of XXY Children

    ERIC Educational Resources Information Center

    Walzer, Stanley; And Others

    1978-01-01

    This report summarizes preliminary results from a behavioral study of 13 male infants who were ascertained to have an XX Y sex chromosome complement at birth and who are being followed longitudinally through early ontogenesis. (CM)

  7. Are There Disorders or Conditions Associated with Primary Ovarian Insufficiency (POI)?

    MedlinePlus

    ... POI can contribute to anxiety or lead to depression. 3 Women diagnosed with POI can be shy, anxious in ... D. E., Calis, K. A., et al. (2011). Depression in women with spontaneous 46, XX primary ovarian insufficiency. Journal ...

  8. 75 FR 45098 - Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration RIN 0648-XX95 Magnuson-Stevens Act Provisions; General Provisions for Domestic Fisheries; Application for Exempted Fishing Permits AGENCY: National Marine...

  9. 48 CFR 752.7003 - Documentation for payment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... information to be reported with the following elements: Total Expenditures Line item No. Description Amt. vouchered to date Amt. vouchered this period 001 Product/Service Desc. for Line Item 001 $XXXX.XX $...

  10. Astronautics: Past, present and future

    NASA Astrophysics Data System (ADS)

    Maksimov, A. I.

    2016-10-01

    The article deals with the beginning and evolution of astronautics in XX-XXI centuries. The great attention is paid to the contribution of private companies to the further expansion of the mankind space activities in the past few decades.

  11. 77 FR 67678 - Content Specifications and Shielding Evaluations for Type B Transportation Packages

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-13

    ... COMMISSION Content Specifications and Shielding Evaluations for Type B Transportation Packages AGENCY... Regulatory Issue Summary (RIS) 2012-XX, ``Content Specifications and Shielding Evaluations for Type B... Plan for Transport Packages for Radioactive Material,'' for the review of content specifications...

  12. Improving the Defense Acquisition System and Reducing System Costs

    DTIC Science & Technology

    1981-03-30

    Reliability Bendix Corporation Mr. Arnold Pazomik Assistant Vice President and Director of Contracts ARINC Research Corporation Mr. Harvey Kishner...Acquisition Executive 4 8 E. DSARC Review Criteria 49 F. DSARC-PPBS Interface 50 G. Program Manager Control 52 H. Improving Reliability and Support 54... Reliability and Support X X USDRE X X 17. Reduce DSARC Briefing and Data Requirements X X USDRE X XX XX 18. Budgeting for Inflation X X ASD(C

  13. Emulating the 1-Dimensional Fermi-Hubbard Model with Superconducting Qubits

    NASA Astrophysics Data System (ADS)

    Reiner, Jan-Michael; Marthaler, Michael; Schön, Gerd

    A chain of qubits with both ZZ and XX couplings is described by a Hamiltonian which coincides with the Fermi-Hubbard model in one dimension. The qubit system can thus be used to study the quantum properties of this model. We investigate the specific implementation of such an analog quantum simulator by a chain of tunable Transmon qubits, where the ZZ interaction arises due to an inductive coupling and the XX interaction due to a capacitive coupling.

  14. Molecular analysis in true hermaphrodites with different karyotypes and similar phenotypes

    SciTech Connect

    Torres, L.; Cervantes, A.; Kofman-Alfaro, S.

    1996-05-17

    True hermaphroditism is characterized by the development of ovarian and testicular tissue in the same individual. Muellerian and Wolffian structures are usually present, and external genitalia are often ambiguous. The most frequent karyotype in these patients is 46,XX or various forms of mosaicism, whereas 46,XY is very rarely found. The phenotype in all these subjects is similar. We studied 10 true hermaphrodites. Six of them had a 46,XX chromosomal complement: 3 had been reared as males and 3 as females. The other 4 patients were mosaics: 3 were 46,XX/46,XY and one had a 46,XX/47,XXY karyotype. One of the 46,XX/46,XY mosaics was reared as a female, whereas the other 3 mosaics were reared as males. The sex of assignment in the 10 patients depended only on labio-scrotal differentiation. Molecular studies in 46,XX subjects documented the absence of Y centromeric sequences in all cases, arguing against hidden mosaicism. One patient presented Yp sequences (ZFY+, SRY+), which contrast with South African black 46,XX true hermaphrodites in whom no Y sequences were found. Molecular analysis in the subjects with mosaicism demonstrated the presence of Y centromeric and Yp sequences confirming the presence of a Y chromosome. Gonadal development, endocrine function, and phenotype in the 10 patients did not correlate with the presence of a Y chromosome or Y-derived sequences in the genome, confirming that true hermaphroditism is a heterogeneous condition. Both Mexican and non-South African 46,XX true hermaphrodites may be SRY positive. 51 refs., 3 figs., 2 tabs.

  15. Prenatal diagnosis of female monozygotic twins discordant for Turner syndrome: implications for prenatal genetic counselling.

    PubMed

    Gilbert, B; Yardin, C; Briault, S; Belin, V; Lienhardt, A; Aubard, Y; Battin, J; Servaud, M; Philippe, H J; Lacombe, D

    2002-08-01

    We describe a set of monozygotic (MZ) female twins, one of whom presented with a typical Turner syndrome (TS) phenotype and the other a normal female phenotype. Prenatal fetal ultrasonographic examination showed a monochorial diamniotic pregnancy with a hygroma colli and growth delay in Twin A and no anomalies in Twin B. Karyotypic analysis performed on fetal blood samples demonstrated a 46,XX/45,X (23/2) mosaicism in Twin A and a normal 46,XX chromosome constitution in Twin B. At birth, Twin A presented with a typical TS and Twin B had a normal female phenotype. Postnatal cytogenetic investigation of blood lymphocytes showed the same 46,XX/45,X mosaicism in both twins: 46,XX/45,X (40/7) in Twin A and 46,XX/45,X (40/5) in Twin B. Further investigations at the age of 10 months showed in Twin A a 46,XX/45,X (98/2) mosaicism in lymphocytes and 100% of 45,X (50 analysed cells) in fibroblasts, and in Twin B a normal 46,XX (100 analysed cells) chromosome constitution in lymphocytes but a mild 46,XX/45,X (78/2) mosaicism in fibroblasts. Monozygosity was confirmed by molecular analysis. To our knowledge, this is the first report of prenatal diagnosis of MZ female twins discordant for TS. Review of reported sets of MZ female twins (eight cases) or triplets (one case) discordant for TS shows, as in the present case, that the phenotype correlates better with the chromosomal distribution of mosaicism in fibroblasts than in lymphocytes. In the blood of MZ twins chimerism may modify the initial allocation of the mosaicism. These results suggest that, in cases of prenatal diagnosis of MZ female twins discordant for TS, the phenotype of each twin would be better predicted from karyotype analysis of cells from amniotic fluid than from fetal blood.

  16. Complete trisomy 14 mosaicism: first live-born case in Korea

    PubMed Central

    Hwang, Taegyu

    2012-01-01

    Trisomy 14 mosaicism is a rare chromosome disorder characterized by delayed development, failure to thrive, and facial dysmorphism. Only approximately 30 trisomy 14 mosaicism cases have been reported in the literature because trisomy 14 is associated with early spontaneous abortion. We report a case of a 17-month-old girl with abnormal skin pigmentation, delayed development, facial dysmorphism, and failure to thrive with the 47,XX,+14/46,XX chromosome complement. PMID:23133487

  17. Swine Leukocyte Antigen (SLA) class I allele typing of Danish swine herds and identification of commonly occurring haplotypes using sequence specific low and high resolution primers.

    PubMed

    Pedersen, Lasse Eggers; Jungersen, Gregers; Sorensen, Maria Rathmann; Ho, Chak-Sum; Vadekær, Dorte Fink

    2014-12-15

    The swine major histocompatibility complex (MHC) genomic region (SLA) is extremely polymorphic comprising high numbers of different alleles, many encoding a distinct MHC class I molecule, which binds and presents endogenous peptides to circulating T cells of the immune system. Upon recognition of such peptide-MHC complexes (pMHC) naïve T cells can become activated and respond to a given pathogen leading to its elimination and the generation of memory cells. Hence SLA plays a crucial role in maintaining overall adaptive immunologic resistance to pathogens. Knowing which SLA alleles that are commonly occurring can be of great importance in regard to future vaccine development and the establishment of immune protection in swine through broad coverage, highly specific, subunit based vaccination against viruses such as swine influenza, porcine reproductive and respiratory syndrome virus, vesicular stomatitis virus, foot-and-mouth-disease virus and others. Here we present the use of low- and high-resolution PCR-based typing methods to identify individual and commonly occurring SLA class I alleles in Danish swine. A total of 101 animals from seven different herds were tested, and by low resolution typing the top four most frequent SLA class I alleles were those of the allele groups SLA-3*04XX, SLA-1*08XX, SLA-2*02XX, and SLA-1*07XX, respectively. Customised high resolution primers were used to identify specific alleles within the above mentioned allele groups as well as within the SLA-2*05XX allele group. Our studies also suggest the most common haplotype in Danish pigs to be Lr-4.0 expressing the SLA-1*04XX, SLA-2*04XX, and SLA-3*04XX allele combination.

  18. Application of optical analyzer technique for measurements of sound velocities in shock-compressed Al-Mn alloy for calibration of recent elastic-viscous-plastic models

    SciTech Connect

    Kozlov, E. A.; Tarzhanov, V. I.; Pankratov, D. G.; Yakunin, A. K.; Yelkin, V. M.; Mikhailov, V. N.

    2006-08-03

    Registration results of longitudinal CL({sigma}XX) and volume CB({sigma}XX) sound velocities in shock-compressed aluminum alloy are presented. Experimental data were obtained in wide range of longitudinal stress, including the stress, corresponding to solid-liquid shock-induced transformation. By using experimentally measured values of sound velocities, the changes of Poisson ratio and shear modulus were calculated along the shock adiabat. These data are needed for calibration of resent elastic-viscous-plastic models.

  19. Coherence and Polarization Properties of Far Fields Generated by Quasi-Homogeneous Planar Electromagnetic Sources (Postprint)

    DTIC Science & Technology

    2005-02-03

    the explicit dependence of all he parameters on the frequency. In order that the elec- romagnetic Gaussian Schell - model source generated by eans of the...the far field gener- ted by a planar electromagnetic Gaussian Schell - model ource are given by the expressions s1 rs, = xx 2 exp− xx 2 k2 2/2...uniformly polarized, quasi- omogeneous Gaussian Schell - model source, which is haracterized by a cross-spectral density matrix J rs ,rs , whose

  20. Use of a novel two-dimensional ionization chamber array for pencil beam scanning proton therapy beam quality assurance.

    PubMed

    Lin, Liyong; Kang, Minglei; Solberg, Timothy D; Mertens, Thierry; Baeumer, Christian; Ainsley, Christopher G; McDonough, James E

    2015-05-08

    The need to accurately and efficiently verify both output and dose profiles creates significant challenges in quality assurance of pencil beam scanning (PBS) proton delivery. A system for PBS QA has been developed that combines a new two-dimensional ionization chamber array in a waterproof housing that is scanned in a water phantom. The MatriXX PT has the same detector array arrangement as the standard MatriXX(Evolution) but utilizes a smaller 2 mm plate spacing instead of 5mm. Because the bias voltage of the MatriXX PT and Evolution cannot be changed, PPC40 and FC65-G ionization chambers were used to assess recombination effects. The PPC40 is a parallel plate chamber with an electrode spacing of 2mm, while the FC65-G is a Farmer chamber FC65-G with an electrode spacing of 2.8 mm. Three bias voltages (500, 200, and 100 V) were used for both detectors to determine which radiation type (continuous, pulse or pulse-scanned beam) could closely estimate Pion from the ratios of charges collected. In comparison with the MatriXX(Evolution), a significant improvement in measurement of absolute dose with the MatriXX PT was observed. While dose uncertainty of the MatriXX(Evolution) can be up to 4%, it is < 1% for the MatriXX PT. Therefore the MatriXX(Evolution) should not be used for QA of PBS for conditions in which ion recombination is not negligible. Farmer chambers should be used with caution for measuring the absolute dose of PBS beams, as the uncertainty of Pion can be > 1%; chambers with an electrode spacing of 2 mm or smaller are recommended.

  1. 18 CFR Appendix B to Subpart H of... - Appendix B to Subpart H of Part 35

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Corp ABC Corp NA* ABC balancing authority area Central 8/12/1981 153.5 MW (seasonal). xyz Inc. ER94-79XX-000 NA NA NA NA NA NA NA NA. RST LLC ER01-2XX5-000 Green CoGen WWW Corp RST LLC 5/23/2005 New York... 2/1/1982 Sample Co. balancing authority Southwest 5/13/1973 10 MW (seasonal). *If an entity has......

  2. 18 CFR Appendix B to Subpart H of... - Appendix B to Subpart H of Part 35

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Corp ABC Corp NA* ABC balancing authority area Central 8/12/1981 153.5 MW (seasonal). xyz Inc. ER94-79XX-000 NA NA NA NA NA NA NA NA. RST LLC ER01-2XX5-000 Green CoGen WWW Corp RST LLC 5/23/2005 New York... 2/1/1982 Sample Co. balancing authority Southwest 5/13/1973 10 MW (seasonal). *If an entity has......

  3. 18 CFR Appendix B to Subpart H of... - Appendix B to Subpart H of Part 35

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Corp ABC Corp NA* ABC balancing authority area Central 8/12/1981 153.5 MW (seasonal). xyz Inc. ER94-79XX-000 NA NA NA NA NA NA NA NA. RST LLC ER01-2XX5-000 Green CoGen WWW Corp RST LLC 5/23/2005 New York... 2/1/1982 Sample Co. balancing authority Southwest 5/13/1973 10 MW (seasonal). *If an entity has......

  4. CBR-D Tactical Decision Aid (DECAID) Identification and Analysis of Predictive Human Performance Models and Data Bases for Use in a Commander’s CBR-D Decision Aid (DECAID)

    DTIC Science & Technology

    1988-10-15

    x .9996 x .9990 - .9952 The application of the AIR Data Store...time: adequate; restricted coo ro l Pobabiliy Estimate I.o Wx x x x x .999 (2) X X X X .9990 (3) XX IC X .9965(3) x x x x .996 (14) X X X X .9973 (5... X - x .9952 (6) x x x x .9873 (7) x xx x .9977 (8) X

  5. Trisomy 21 with 47,+18 lymphocyte cell line: double mitotic nondisjunction.

    PubMed Central

    Jenkins, M B; Kriel, R L; Boyd, L; Barnwell, A

    1978-01-01

    A patient with Down's syndrome was found to have 47,XX,+18/47,XX,+21 mosaicism. Chromosome 18 trisomy was found only in 18% of lymphocytes and not in skin fibroblasts. A likely interpretation is double nondisjunction in a single lymphocyte precursor of a trisomy 21 embryo. A brief review of other cases of mitotic multiple nondisjunction and double aneuploid mosiacism is presented. Images PMID:153975

  6. Specifiers Properties Information Exchange (SPie): Minimum Building Information Model (BIM) Object Definitions

    DTIC Science & Technology

    2013-03-01

    speed pumping system – hydro-pneumatic water pressure system – variable speed pumping system Compressed Air System UFGS 2.14 n/a air compressors...booster pumps – sewage pumps Water Pressure Booster System UFGS 2.20 n/a constant speed pumping system – variable speed pumping system...00 Variable Speed Drives Name COBie Guide n/a Type XX Space#-01 Type COBie Guide n/a Type XX Location COBie Guide n/a space name

  7. Sex chromosome complement involvement in angiotensin receptor sexual dimorphism.

    PubMed

    Dadam, Florencia M; Cisternas, Carla D; Macchione, Ana F; Godino, Andrea; Antunes-Rodrigues, José; Cambiasso, María J; Vivas, Laura M; Caeiro, Ximena E

    2017-02-27

    This study aimed to define whether sex chromosome complement (SCC) may differentially modulate sex differences in relative gene expression of basal Agtr1a, Agtr2, and Mas1 receptors at fore/hindbrain nuclei and at medulla/cortical kidney. Samples were collected from gonadectomized male (XX and XY) and female (XX and XY) mice of the "four core genotypes" model. At brain level, a SCC effect at the area postrema was demonstrated. An increase in mRNA level of Agtr1a and Agtr1a/Agtr2 ratio in XY-SCC mice was associated with a decrease in Mas1 compared to XX-SCC mice. In the renal cortex, a SCC effect for Agtr2 and Mas1 was observed. Regardless of sex (male or female), XX-SCC mice expressed higher levels of mRNA Agtr2 and Mas1 than XY-SCC mice {F(1,12) = 6,126,p < 0.05; F(1,21) = 5,143,p < 0.05}. Furthermore, XX-female mice showed a significant increase in Mas1 expression compared to XY-female mice. These results reveal a SCC modulatory effect at central and kidney level on angiotensin receptor expression, with an enhancement of the vasodilatory arm in XX-mice and an increase in the vasoconstriction arm in XY-mice, which may underlie sex differences in the regulation of arterial pressure.

  8. Mosaic variegated aneuploidy associated with a dysmorphic syndrome and mental handicap

    SciTech Connect

    Mehta, L.; Babu, A.; Willner, J.

    1994-09-01

    A 41-year-old woman was evaluated for dysmorphic features and mental handicap. Prior karyotyping had revealed 7% mosaicism for trisomy 18 in skin fibroblasts with normal blood chromosomes. Clinical features consisted of short stature, mild mental retardation, sensorineural deafness and the following dysmorphic features: short, broad neck, low posterior hairline, small palpebral fissures with iris coloboma on the right, epicanthic folds, small mouth, high palate and prominent mandible, short metacarpals and digits, particularly the fifth, with bilateral simian creases. Medical problems included non-insulin dependent diabetes mellitus, hypertension, oligomenorrhea and recent onset of diabetic neuropathy and retinal exudates. Head size and brain MRI were within normal limits. Peripheral blood chromosomes revealed: 46,XX (45 cells), 46,XX,t(7;16)(q21;q21) in 1 cell, 45,X (1 cell), 48,XXXX (1 cell), 47,XX,+mar (1 cell), 48,XX,+mar,+mar (1 cell). Skin fibroblasts revealed the following karyotypes: 46,XX (25 cells), 45,X (14 cells), 47,XX,+2 (10 cells) and 47,X,+2,+7 (1 cell). Previously reported cases of mosaic variegated aneuploidy include microcephaly as a prominent feature. Chromosomes involved in the abnormality are variable. Clinical presentations in such patients are not consistent and do not appear to correlate with specific chromosome defects. This patient represents an interesting example of probable mitotic instability disrupting normal developmental processes.

  9. Domain Analysis of a Modular α-l-Arabinofuranosidase with a Unique Carbohydrate Binding Strategy from the Fiber-Degrading Bacterium Fibrobacter succinogenes S85 ▿ †

    PubMed Central

    Yoshida, Shosuke; Hespen, Charles W.; Beverly, Robert L.; Mackie, Roderick I.; Cann, Isaac K. O.

    2010-01-01

    Family 43 glycoside hydrolases (GH43s) are known to exhibit various activities involved in hemicellulose hydrolysis. Thus, these enzymes contribute to efficient plant cell wall degradation, a topic of much interest for biofuel production. In this study, we characterized a unique GH43 protein from Fibrobacter succinogenes S85. The recombinant protein showed α-l-arabinofuranosidase activity, specifically with arabinoxylan. The enzyme is, therefore, an arabinoxylan arabinofuranohydrolase (AXH). The F. succinogenes AXH (FSUAXH1) is a modular protein that is composed of a signal peptide, a GH43 catalytic module, a unique β-sandwich module (XX domain), a family 6 carbohydrate-binding module (CBM6), and F. succinogenes-specific paralogous module 1 (FPm-1). Truncational analysis and site-directed mutagenesis of the protein revealed that the GH43 domain/XX domain constitute a new form of carbohydrate-binding module and that residue Y484 in the XX domain is essential for binding to arabinoxylan, although protein structural analyses may be required to confirm some of the observations. Kinetic studies demonstrated that the Y484A mutation leads to a higher kcat for a truncated derivative of FSUAXH1 composed of only the GH43 catalytic module and the XX domain. However, an increase in the Km for arabinoxylan led to a 3-fold decrease in catalytic efficiency. Based on the knowledge that most XX domains are found only in GH43 proteins, the evolutionary relationships within the GH43 family were investigated. These analyses showed that in GH43 members with a XX domain, the two modules have coevolved and that the length of a loop within the XX domain may serve as an important determinant of substrate specificity. PMID:20709893

  10. Impacts of coulomb interactions on the magnetic responses of excitonic complexes in single semiconductor nanostructures.

    PubMed

    Chang, Wen-Hao; Lin, Chia-Hsien; Fu, Ying-Jhe; Lin, Ta-Chun; Lin, Hsuan; Cheng, Shuen-Jen; Lin, Sheng-Di; Lee, Chien-Ping

    2010-01-21

    We report on the diamagnetic responses of different exciton complexes in single InAs/GaAs self-assembled quantum dots (QDs) and quantum rings (QRs). For QDs, the imbalanced magnetic responses of inter-particle Coulomb interactions play a crucial role in the diamagnetic shifts of excitons (X), biexcitons (XX), and positive trions (X-). For negative trions (X-) in QDs, anomalous magnetic responses are observed, which cannot be described by the conventional quadratic energy shift with the magnetic field. The anomalous behavior is attributed to the apparent change in the electron wave function extent after photon emission due to the strong Coulomb attraction by the hole in its initial state. In QRs, the diamagnetic responses of X and XX also show different behaviors. Unlike QDs, the diamagnetic shift of XX in QRs is considerably larger than that of X. The inherent structural asymmetry combined with the inter-particle Coulomb interactions makes the wave function distribution of XX very different from that of X in QRs. Our results suggest that the phase coherence of XX in QRs may survive from the wave function localization due to the structural asymmetry or imperfections.

  11. [Blood cell chimerism in dizygotic twins conceived by in vitro fertilization].

    PubMed

    Martos-Moreno, G Á; Campos, C; Flores, R; Yturriaga, R; Pérez-Jurado, L A; Argente, J

    2013-10-01

    We present a case of hematopoietic chimerism in dizygotic twins (male and female) conceived by in vitro fertilization (IVF). At 8 years of age a blood karyotype was performed on the female due to the presence of clitoromegaly. Two different lines: 46,XX (53%) and 46,XY (47%) were found. FISH studies confirmed the presence of the SRY gene in 46,XY cells. Karyotyping of the male showed two different lines: 46,XY (58%) and 46,XX (42%). SRY gene was present in 46,XY cells. Microsatellite analyses of blood DNA revealed tetra-allelic contribution at some autosomal loci with similar proportions of maternal and paternal alleles and X/Y chromosome dose. FISH in buccal mucous showed that all cells from the female were 46,XX and those from the male 46,XY. The gonadal karyotype in the female was 46,XX without SRY. Hence, we report 46,XX/46,XY chimerism in dizygotic twins. Blood chimerism was confirmed by performing FISH on the buccal cells of the patients.

  12. Abnormalities of gonadal differentiation.

    PubMed

    Berkovitz, G D; Seeherunvong, T

    1998-04-01

    Gonadal differentiation involves a complex interplay of developmental pathways. The sex determining region Y (SRY) gene plays a key role in testis determination, but its interaction with other genes is less well understood. Abnormalities of gonadal differentiation result in a range of clinical problems. 46,XY complete gonadal dysgenesis is defined by an absence of testis determination. Subjects have female external genitalia and come to clinical attention because of delayed puberty. Individuals with 46,XY partial gonadal dysgenesis usually present in the newborn period for the valuation of ambiguous genitalia. Gonadal histology always shows an abnormality of seminiferous tubule formation. A diagnosis of 46,XY true hermaphroditism is made if the gonads contain well-formed testicular and ovarian elements. Despite the pivotal role of the SRY gene in testis development, mutations of SRY are unusual in subjects with a 46,XY karyotype and abnormal gonadal development. 46,XX maleness is defined by testis determination in an individual with a 46,XX karyotype. Most affected individuals have a phenotype similar to that of Klinefelter syndrome. In contrast, subjects with 46,XX true hermaphroditism usually present with ambiguous genitalia. The majority of subjects with 46,XX maleness have Y sequences including SRY in genomic DNA. However, only rare subjects with 46,XX true hermaphroditism have translocated sequences encoding SRY. Mosaicism and chimaerism involving the Y chromosome can also be associated with abnormal gonadal development. However, the vast majority of subjects with 45,X/46,XY mosaicism have normal testes and normal male external genitalia.

  13. Confirmation of Down syndrome critical region by FISH analysis in a patient with add(21)(p11)

    SciTech Connect

    Matsumoto, Naomichi; Niikawa, Norio; Mikawa, Makoto

    1995-12-04

    We have studied a patient with clinical Down syndrome (DS) who has a mosaic 46, XX/46, XX, 21p+ karyotype. The patient was born at 39 weeks of gestation with a birth weight of 3,025 g to healthy parents. At age 2 months, she was diagnosed clinically to have DS; she had flat facies, upslanted palpebral fissures, epicanthal folds, telecanthus, flat nasal bridge, abnormal dentition, malformed ears, short neck, short fingers, clinodactyly with single flexion crease of the fifth fingers, hyperextension of joints, pes planus, distal axial triradii, and bilateral tibial arch patterns. Chromosome analysis showed mosaicism consisting of a normal 46,XX cell line and a line with a 21p+ chromosome, the final karyotype being mos46,XX[57]/46,XX,add(21)(p11)[43]. Although the origin of an additional segment on chromosome 21 was not identified with conventional banding analyses, it was suspected to represent partial trisomy 21 on the basis of clinical manifestations. 6 refs., 2 figs.

  14. High temperature causes masculinization of genetically female medaka by elevation of cortisol.

    PubMed

    Hayashi, Yuki; Kobira, Hiroshi; Yamaguchi, Toshiya; Shiraishi, Eri; Yazawa, Takashi; Hirai, Toshiaki; Kamei, Yasuhiro; Kitano, Takeshi

    2010-08-01

    In poikilothermic vertebrates, sex determination is sometimes influenced by environmental factors such as temperature. However, little is known about the molecular mechanisms underlying environmental sex determination. The medaka (Oryzias latipes) is a teleost fish with an XX/XY sex determination system. Recently, it was reported that XX medaka can be sex-reversed into phenotypic males by high water temperature (HT; 32-34 degrees C) treatment during the sex differentiation period. Here we report that cortisol caused female-to-male sex reversal and that metyrapone (an inhibitor of cortisol synthesis) inhibited HT-induced masculinization of XX medaka. HT treatment caused elevation of whole-body levels of cortisol, while metyrapone suppressed the elevation by HT treatment during sexual differentiation. Moreover, cortisol and 33 degrees C treatments inhibited female-type proliferation of germ cells as well as expression of follicle-stimulating hormone receptor (fshr) mRNA in XX medaka during sexual differentiation. These results strongly suggest that HT induces masculinization of XX medaka by elevation of cortisol level, which, in turn, causes suppression of germ cell proliferation and of fshr mRNA expression.

  15. Splitting of the zero-energy Landau level and universal dissipative conductivity at critical points in disordered graphene.

    PubMed

    Ortmann, Frank; Roche, Stephan

    2013-02-22

    We report on robust features of the longitudinal conductivity (σ(xx)) of the graphene zero-energy Landau level in the presence of disorder and varying magnetic fields. By mixing an Anderson disorder potential with a low density of sublattice impurities, the transition from metallic to insulating states is theoretically explored as a function of Landau-level splitting, using highly efficient real-space methods to compute the Kubo conductivities (both σ(xx) and Hall σ(xy)). As long as valley degeneracy is maintained, the obtained critical conductivity σ(xx) =/~ 1.4e(2)/h is robust upon an increase in disorder (by almost 1 order of magnitude) and magnetic fields ranging from about 2 to 200 T. When the sublattice symmetry is broken, σ(xx) eventually vanishes at the Dirac point owing to localization effects, whereas the critical conductivities of pseudospin-split states (dictating the width of a σ(xy) = 0 plateau) change to σ(xx) =/~ e(2)/h, regardless of the splitting strength, superimposed disorder, or magnetic strength. These findings point towards the nondissipative nature of the quantum Hall effect in disordered graphene in the presence of Landau level splitting.

  16. Evaluation of Anticorrosion Performance of New Materials for Alternative Superheater Tubes in Biomass Power Plants

    NASA Astrophysics Data System (ADS)

    Li, Yuchun; Zhang, Hongliang; He, Yuwu

    2016-09-01

    One way of controlling alkali chloride-induced corrosion in biomass boilers is by designing new alloy materials used as superheater tubes. Four newly designed Cr-Ni alloy was designed and studied for applicability in biomass power plants. High-temperature oxidation experiments and high-temperature corrosion experiments were carried out for evaluation material characterization. Through analysis and discussion of the corrosion kinetics and oxidation kinetics, it can be concluded that materials with series number of "2xx" and "3xx" had better endurance ability in KCl environment under 650°C and 700°C than TP316 material. In the same conditions, 3xx material had better anticorrosion ability in 700°C with KCl environment.

  17. Prenatal diagnosis of mosaic ring 22 duplication/deletion with terminal 22q13 deletion due to abnormal first trimester screening and choroid plexus cyst detected on ultrasound.

    PubMed

    Koç, Altuğ; Arisoy, Ozgür; Pala, Elif; Erdem, Mehmet; Kaymak, Ayşegül Oztürk; Erkal, Ozgür; Karaoğuz, Meral Yirmibeş

    2009-10-01

    We report a rare case of mosaic ring chromosome 22 duplication/deletion in a fetus for whom karyotype analysis was required because of an abnormal finding in the maternal serum screening test and a choroid plexus cyst detected on prenatal ultrasound. Additional prenatal study of the amniotic fluid by fluorescence in situ hybridization was performed and the terminal 22q13.3 deletion was detected on ring chromosome. The final karyotype was 45,XX,-22[3]/46,XX,r(22)(p11q13.2)[63]/46,XX,idicr(22)(p11q13.2;p11q13.2)[2]dn.ishder(22)(N25+, ARSA-, ter-). The pegnancy was terminated. Cytogenetic analysis of the intracardiac blood also revealed ring 22 mosaicism with only one metaphase spread with idicr(22) as the unstable isodicentric rings are subsequently lost from most cells. We discuss the prenatal diagnosis of this rare condition.

  18. The Pallister-Killian syndrome in a child with rare karyotype--a diagnostic problem.

    PubMed

    Smigiel, Robert; Pilch, Jacek; Makowska, Izabela; Busza, Halina; Slezak, Ryszard; Sasiadek, Maria M

    2008-09-01

    The Pallister-Killian syndrome is a clinically recognizable syndrome, usually due to a tissue-specific mosaicism for a 12p isochromosome [i(12p)]. We report a rare case of Pallister-Killian syndrome with 12p mosaicism, tetrasomy/trisomy/disomy in fibroblasts and trisomy/disomy in lymphocytes. Marker chromosomes were investigated with conventional cytogenetic techniques and fluorescent in situ hybridisation (FISH). The karyotype was established as: mos47,XX,+12p/47,XX,+i(12p)/46,XX. The cytogenetic result of the extra mosaic 12p presented in lymphocytes suggested the diagnosis of trisomy 12p, although, in combination with clinical manifestations, the Pallister-Killian syndrome was considered and confirmed by the cytogenetic analysis of fibroblasts.

  19. Clinical Differences Between Monomicrobial and Polymicrobial Vertebral Osteomyelitis.

    PubMed

    Issa, Kimona; Pourtaheri, Sina; Stewart, Tyler; Faloon, Michael; Sahai, Nikhil; Mease, Samuel; Sinha, Kumar; Hwang, Ki; Emami, Arash

    2016-11-11

    Little literature exists examining differences in presentation and outcomes between monomicrobial and polymicrobial vertebral infections. Seventy-nine patients treated for vertebral osteomyelitis between 2001 and 2011 were reviewed. Patients were divided into monomicrobial and polymicrobial cohorts based on type of infection. Various characteristics were compared between the 2 groups. The 26 patients with a polymicrobial infection were older and had a higher mortality rate, lower clearance of infection, larger infection, more vertebral instability, higher erythrocyte sedimentation rate at presentation, and longer mean length of stay. There were no significant differences in Oswestry Disability Index scores at final follow-up, but there were differences in presentation and clinical outcomes between monomicrobial and polymicrobial vertebral osteomyelitis. Patients may benefit from counseling regarding their disease type and potential prognosis. [Orthopedics. 201x; xx(x):xx-xx.].

  20. Optimality Self Online Monitoring (OSOM) for Performance Evaluation and Adaptive Sensor Fusion

    DTIC Science & Technology

    2008-07-01

    SNO ) are given by: 2 2 )24( 232 w sno xP σβαα ααββ −− +−= (5a) 2 )24( )2( w sno xx T P σ...βαα βαβ −− −= (5b) 2 2 2 )24( 2 w sno x T P σ βαα β −− = (5c) which show the reduction of variances of the filtered state as compared to the...gives the maximum RMS errors in position and velocity errors: maxmax A x sno xx PPRMS += (9a) maxmax A x sno xx PPRMS += (9b) where Amax is