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Sample records for atomnoi energetike xx

  1. Manpower Management (Officer and Enlisted) AFSC 74XX/733XX

    DTIC Science & Technology

    1989-03-01

    OCCUPATIONAL ANALYSIS PROGRAM USAF OCCUPATIONAL MEASUREMENT CENTER AIR TRAINING COMMAND RANDOLPH AFB, TEXAS 78160-5000 APPROVED FOR PUBLIC RELEASE...Previous Survey Findings .. .. ..... ........ ........ ...... 35 SECTION IV. .. ...... ....... ........ ........ 38 ANALYSIS OF DAFSC 74XX/733XX...42 Officer DAFSC Descriptions and Comparisons. .. ...... .... 42 Summary .. .. ..... ........ ....... ........ 47 ANALYSIS OF AFR 36-1 AND AFR 39-1

  2. Leprechaunism with mosaicism 46, XX/47, XX extra ring chromosome.

    PubMed Central

    Ventruto, V; Sebastio, L; Sebastio, G; DeMasi, R V; Vota, U; Farina, L; Festa, B

    1977-01-01

    A case of leprechaunism with a chromosomal abnormality is reported. The patient was a female infant, born to healthy, consanguineous young parents. Her course was one of extreme marasmus, with death at 3 months of age. She presented the classical features of the syndrome and chromosome mosaicism 46, XX/47, XX, +r(?). It was not possible to identify the origin of the extra ring chromosome. It is difficult to establish the role of such a cytogenetic finding in the aetiology of the syndrome. Images PMID:592357

  3. PAH emission in XX Ophiuchi

    NASA Astrophysics Data System (ADS)

    Evans, E.

    1994-08-01

    Infrared spectra of the ζ Aur/VV Cep system XX Oph are presented. Contrary to a suggestion of Evans et al. (1993) the 10 μm spectrum shows no silicate emission but instead shows evidence of PAH emission. The infrared emission and the extinction in the blue are consistent with PAH molecules containing ~30-50 carbon atoms.

  4. Monozygotic twin discordant for Down syndrome: mos 47,XX,+21/46,XX and 46,XX.

    PubMed

    Choi, Sun Ah; Ko, Jung Min; Shin, Choong Ho; Yang, Sei Won; Choi, Jin Sun; Oh, Sun Kyung

    2013-08-01

    Monozygotic twins, developed from a single zygote, are almost identical in clinical phenotype and concordant karyotypes. Monozygotic twins with discordant karyotypes are thought to be quite rare. Here, we report monochorionic-diamniotic twins discordant for Down syndrome. On findings of prenatal ultrasonography, nuchal translucency thickness was different between twins, and suggested that one of the twins was at high risk for having chromosomal abnormalities including Down syndrome. The twins were monochorionic-diamniotic; therefore, chorionic villi sampling of the common placenta was performed. The karyotype of the chorionic villi cells was 46,XX, and pregnancy was maintained. After delivery, dysmorphic clinical features suggesting Down syndrome were found in one of the twins, while the other twin showed a morphologically normal appearance. Karyotypes of peripheral blood leukocytes were repeatedly normal in the dysmorphic twin; however, the karyotype of skin fibroblasts from the dysmorphic twin indicated Down syndrome mosaicism; 47,XX,+21[99]/46,XX[2]. The karyotype of skin fibroblasts from the morphologically normal twin was 46,XX. Monozygosity of the twins was confirmed by a short tandem repeat analysis using 16 polymorphic markers. A mitotic nondisjunction followed by the twinning would explain the discordant karyotypes between monozygotic twins.

  5. XX Pyxidis: the Mummy returns

    NASA Astrophysics Data System (ADS)

    Handler, G.

    2002-02-01

    An overview of the work devoted to the delta Sct star XX Pyx within this Flanders-South Africa bilateral programme is given. We first review the motivations for investigating this object in detail, and we explain its importance for asteroseismology of delta Sct stars in general. We continue by pointing out the public availability of the time series photometric data of the star through a FLANSA collaboration, and then look back on the finding that XX Pyx is actually located in a binary system. Finally, we briefly discuss the evidence for anomalous cycles occurring in the star's light curves and we finish by summarizing what we have learned from the star and what may still be done in the future.

  6. 49 CFR 1242.30 - Dismantling retired road property and depreciation (accounts XX-17-39, XX-18-39, XX-19-39, 62-17...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Dismantling retired road property and depreciation (accounts XX-17-39, XX-18-39, XX-19-39, 62-17-00, 62-18-00, and 62-19-00). 1242.30 Section 1242.30....30 Dismantling retired road property and depreciation (accounts XX-17-39, XX-18-39, XX-19-39,...

  7. 49 CFR 1242.55 - Administration (account XX-51-01).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Trains (XX-51-58) Operating Signals and Interlockers (XX-51-59) Operating Drawbridges (XX-51-60) Highway...) Electric Power Purchased/Produced for Motive Power (XX-51-68) Servicing Locomotives (XX-51-69)...

  8. The reddening and variability of XX Ophiuchi

    NASA Technical Reports Server (NTRS)

    Evans, A.; Albinson, J. S.; Barrett, P.; Davies, J. K.; Goldsmith, M. J.; Hutchinson, M. G.; Maddison, R. C.

    1993-01-01

    We present polarization data on the XX Oph system which suggest that the interstellar extinction to this object has been overestimated in the past: our data imply A(V) = 1.6 mag. Our photometry and infrared spectroscopy suggest a spectral class of M7III for the late component, and a BOV companion that ionizes the wind of the cool component. XX Oph seems more like a Zeta Aur/VV Cep system than a 'symbiotic object'. The photometric variability of XX Oph seems to have a number of causes, ranging from shell-type variability in the U band to variations in the M component in the infrared.

  9. Roadmap Through Title XX. Financing Services for Children Through Title XX and Other Programs: Manual 5.

    ERIC Educational Resources Information Center

    Copeland, William C.; Iversen, Iver A.

    This manual, part of a Hecht Institute four-manual series entitled Financing Children's Services Through Title XX and Related Programs, teaches what Title XX regulations are, what they mean, and what actions and procedures are commanded by them. The first section covers the necessity of rule systems, the characteristics of a good rule system and…

  10. 49 CFR 1242.84 - Marketing, sales, and public relations and advertising (accounts XX-63-88, XX-63-89 and XX-63-93).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Marketing, sales, and public relations and advertising (accounts XX-63-88, XX-63-89 and XX-63-93). 1242.84 Section 1242.84 Transportation Other... PASSENGER SERVICE FOR RAILROADS 1 Operating Expenses § 1242.84 Marketing, sales, and public relations...

  11. Prenatal diagnosis of 45,X/46,XX

    SciTech Connect

    Hsu, L.Y.F.

    1996-03-01

    I read with great interest the paper on {open_quotes}Prenatal Diagnosis of 45,X/46,XX mosaicism and 45,X: Implications for Postnatal Outcome{close_quotes} by Koeberl et al. They reported their experience with 12 prenatally diagnosed cases of 45,X/46,XX mosaicism and made a clinical comparison between those 12 cases and their own 41 postnatally diagnosed cases of 45,X/46,XX mosaicism. As expected, they found an overall milder phenotypic manifestation in the prenatal cases than in the postnatal ones. These authors report a lack of previous prognostic information on this type of prenatally diagnosis of mosaicism and offer their findings to fill this need. However, considerable information on this topic has been published. There have been >200 prenatally diagnosed cases of 45,X/46,XX. According to my data on 189 cases with a prenatal diagnosis of 45,X/46,XX mosaicism (Hsu 1992), there are 114 cases with available information on phenotypic outcome. Of these, 12 (10.5%) were reported to have some features of Turner syndrome, 4 had other anomalies probably not related to Turner syndrome, and 2 resulted in stillbirth. The overall rate for an abnormal phenotype in this category was thus 16/114 (14.03%). However, we must realize that, even in patients with a nonmosaic 45,X complement, the major features of Turner syndrome, such as short stature and sexual infantilism, are manifested only later in childhood or in adolescence. 3 refs.

  12. Genetics Home Reference: 46,XX testicular disorder of sex development

    MedlinePlus

    ... of sex development 46,XX testicular disorder of sex development Enable Javascript to view the expand/collapse ... Close All Description 46,XX testicular disorder of sex development is a condition in which individuals with ...

  13. 49 CFR 1242.10 - Administration-track (account XX-19-02).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) Other Track Materials: Running (21-17-15) Switching (21-18-15) Ballast: Running (21-17-16) Switching (21-18-16) Track Laying and Surfacing: Running (XX-17-17) Switching (XX-18-17) Road Property Damaged: Running (XX-17-48) Switching (XX-18-48) Other (XX-19-48) Dismantling Retired Road Property: Running (XX-17...

  14. 49 CFR 1242.20 - Highway grade crossings (accounts XX-17-22 and XX-18-22).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... RAILROADS 1 Operating Expenses-Way and Structures § 1242.20 Highway grade crossings (accounts XX-17-22 and... 49 Transportation 9 2012-10-01 2012-10-01 false Highway grade crossings (accounts XX-17-22 and XX-18-22). 1242.20 Section 1242.20 Transportation Other Regulations Relating to Transportation...

  15. 49 CFR 1242.20 - Highway grade crossings (accounts XX-17-22 and XX-18-22).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... RAILROADS 1 Operating Expenses-Way and Structures § 1242.20 Highway grade crossings (accounts XX-17-22 and... 49 Transportation 9 2014-10-01 2014-10-01 false Highway grade crossings (accounts XX-17-22 and XX-18-22). 1242.20 Section 1242.20 Transportation Other Regulations Relating to Transportation...

  16. 49 CFR 1242.20 - Highway grade crossings (accounts XX-17-22 and XX-18-22).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... RAILROADS 1 Operating Expenses-Way and Structures § 1242.20 Highway grade crossings (accounts XX-17-22 and... 49 Transportation 9 2013-10-01 2013-10-01 false Highway grade crossings (accounts XX-17-22 and XX-18-22). 1242.20 Section 1242.20 Transportation Other Regulations Relating to Transportation...

  17. 49 CFR 1242.20 - Highway grade crossings (accounts XX-17-22 and XX-18-22).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... RAILROADS 1 Operating Expenses-Way and Structures § 1242.20 Highway grade crossings (accounts XX-17-22 and... 49 Transportation 9 2010-10-01 2010-10-01 false Highway grade crossings (accounts XX-17-22 and XX-18-22). 1242.20 Section 1242.20 Transportation Other Regulations Relating to Transportation...

  18. 49 CFR 1242.20 - Highway grade crossings (accounts XX-17-22 and XX-18-22).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Highway grade crossings (accounts XX-17-22 and XX-18-22). 1242.20 Section 1242.20 Transportation Other Regulations Relating to Transportation... RAILROADS 1 Operating Expenses-Way and Structures § 1242.20 Highway grade crossings (accounts XX-17-22 and...

  19. 49 CFR 1242.56 - Engine crews and train crews (accounts XX-51-56 and XX-51-57).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Engine crews and train crews (accounts XX-51-56 and XX-51-57). 1242.56 Section 1242.56 Transportation Other Regulations Relating to Transportation... RAILROADS 1 Operating Expenses-Transportation § 1242.56 Engine crews and train crews (accounts XX-51-56...

  20. 46,XX DSD: the masculinised female.

    PubMed

    Auchus, Richard J; Chang, Alice Y

    2010-04-01

    The 46,XX disorders of sex development (DSDs) cause virilisation or masculinisation of the female foetus. The final common pathway of all 46,XX DSDs is excess dihydrotestosterone (DHT) or potent foreign androgen in the genital tissue during the critical period of sexual differentiation. Whereas the foetal testis is source of androgen in the male, it is the foetal adrenal that produces the DHT precursors in the female. By understanding the principles of human steroid biosynthesis, the pathogenesis of each disorder may be logically deduced, and treatment strategies are rationally constructed. In practice, however, therapies for many of these diseases are fraught with complications and caveats, and current approaches leave much room for improvement. This review discusses these diseases, their pathogenesis and approaches to therapy. We emphasise areas where improved treatments are sorely needed. Copyright (c) 2009 Elsevier Ltd. All rights reserved.

  1. 9xx high power pump modules

    NASA Astrophysics Data System (ADS)

    Pawlik, Susanne; Sverdlov, Boris; Bättig, Rainer; Schmidt, Berthold; Pfeiffer, Hans-Ulrich; Arlt, Sebastian; Lichtenstein, Norbert; Müller, Jürgen; Troger, Jörg; Valk, Bernd; Harder, Christoph

    2006-02-01

    In this communication we present the characteristics of Bookham's MU7-9xx-01 laser module with multimode fiber output. This latest generation of our multimode modules is designed for light output power of up to 7 W in uncooled operation in the wavelength range between 915 nm and 975 nm. The key element of the module is our new SES8-9xx-01 broad area single emitter. These high power lasers in the 9xx nm wavelength range show a high slope efficiency of up to 1.2 W/A in CW room temperature operation. High efficiency combined with low threshold current and low operation voltage result in a maximum wall plug efficiency of above 65%. Almost 4000 h lifetest data at accelerated conditions are available for the laser diodes. The data give estimated reliability values of below 5 kFIT at operating conditions (between 8 A and 8.5 A injection current at up to 35°C heat sink temperature). The robustness of the new lasers is also illustrated by the fact that no catastrophic mirror damage was observed up to 22.5 W of light output power. The low divergence of the laser beam allows coupling into multimode fiber with 0.15 or 0.22 numerical aperture (NA) with a coupling efficiency above 90% at operation condition. Maximum ex-fiber light output powers of 11.5 W are shown. On module level around 2000 h lifetest data are accumulated without any failure or sign of degradation.

  2. [XX 'pure' gonadal dysgenesis and XYY syndrome].

    PubMed

    Itoh, Naoki; Tsukamoto, Taiji

    2004-02-01

    XX 'pure' gonadal dysgenesis is a disease related to Turner's syndrome. Patients of this disease are characterized by normal female external genitalia, bilateral streak gonads, amenorrhea and sexual infantilism. Recently, it has been reported that point mutations of the FSH receptor gene may be one of cause of this disease. The relationship between criminal behavior and XYY syndrome is still controversial. Increased incidence of disomic sperm in 47,XYY males has been reported by fluorescent in situ hybridization(FISH). Genetic counseling should be done when they undergo intracytoplasmic sperm injection.

  3. Modified 43XX Steels for High Toughness

    DTIC Science & Technology

    1980-04-01

    AL AMMRC TR 80-20 MODIFIED 43XX STEELS FOR HIGH TOUGHNESS T CS.,•, °x ,•, o o,,o,,,sD T I W4 AftELECTE APRIL 1980 J N.J. Kar, V.F. Zackay and E.R...carried out. Isohra tasomions in these steels resulted inn bbaainni 11-v DI FOR Z 47 RITIOW OF I NOV695 IS OBSOLETE UCASFE SECURITY UCLASSIFIEDINOFTI PAGE...this investigation for Si-modified AISI 4330 steel appear to be superior to those for unmodified AISI 4340 and 300-M steels , whilst the strength-tough

  4. Classification of the Enigmatic Variable XX Sct

    NASA Astrophysics Data System (ADS)

    Bonjorni, J.; Samus, N. N.

    1999-12-01

    The irregular variable XX Sct has been ascribed five different variability types since its discovery in 1924, from a Cepheid to a rapid irregular variable. Surprisingly, this 13m star has virtually no mention in recent literature, though its classification is still a mystery. We sought to resolve this puzzle by a careful reexamination of nearly 1200 blue photographic plates of this star at the Maria Mitchell Observatory. These revealed strong irregular variability of up to 2 magnitudes on different time scales, including Algol-like minima with a timescale of 10 days or less. Several possible periods have been found, none of which are particularly convincing. UBV photometry and a low-resolution optical spectrum are consistent with a reddened A star. We tentatively suggest that XX Sct is one of the class of young, intermediate mass Herbig Ae/Be stars known as UXors. Further examination of these data is needed to confirm this classification. This project was supported by the NSF/REU grant AST-9820555.

  5. Comprehensive Social Service Programs for Handicapped Citizens through Title XX.

    ERIC Educational Resources Information Center

    Roten, Shelby Jean

    Reviewed are present and potential services and social programs for handicapped children in Mississippi through purchase of service contracts under Title XX of the Social Security Act. Sections cover the following topics: background and purpose of Title XX which gives states greater control over social service programs, planning state supported…

  6. 49 CFR 1242.56 - Engine crews and train crews (accounts XX-51-56 and XX-51-57).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Engine crews and train crews (accounts XX-51-56 and XX-51-57). 1242.56 Section 1242.56 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) ACCOUNTS, RECORDS...

  7. 49 CFR 1242.36 - Machinery repair and equipment damaged (accounts XX-26-40 and XX-26-48).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Machinery repair and equipment damaged (accounts XX-26-40 and XX-26-48). 1242.36 Section 1242.36 Transportation Other Regulations Relating to... FOR RAILROADS 1 Operating Expenses-Equipment § 1242.36 Machinery repair and equipment damaged...

  8. 49 CFR 1242.19 - Electric power systems (account XX-19-21).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Electric power systems (account XX-19-21). 1242.19... Structures § 1242.19 Electric power systems (account XX-19-21). Separate common expenses on basis of common expenses of electric power purchased or produced for motive power (accounts XX-51-68 and XX-52-68). ...

  9. 49 CFR 1242.19 - Electric power systems (account XX-19-21).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Electric power systems (account XX-19-21). 1242.19... Structures § 1242.19 Electric power systems (account XX-19-21). Separate common expenses on basis of common expenses of electric power purchased or produced for motive power (accounts XX-51-68 and XX-52-68). ...

  10. 49 CFR 1242.19 - Electric power systems (account XX-19-21).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Electric power systems (account XX-19-21). 1242.19... Structures § 1242.19 Electric power systems (account XX-19-21). Separate common expenses on basis of common expenses of electric power purchased or produced for motive power (accounts XX-51-68 and XX-52-68). ...

  11. 49 CFR 1242.19 - Electric power systems (account XX-19-21).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 9 2013-10-01 2013-10-01 false Electric power systems (account XX-19-21). 1242.19... Structures § 1242.19 Electric power systems (account XX-19-21). Separate common expenses on basis of common expenses of electric power purchased or produced for motive power (accounts XX-51-68 and XX-52-68). ...

  12. 49 CFR 1242.19 - Electric power systems (account XX-19-21).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Electric power systems (account XX-19-21). 1242.19... Structures § 1242.19 Electric power systems (account XX-19-21). Separate common expenses on basis of common expenses of electric power purchased or produced for motive power (accounts XX-51-68 and XX-52-68). ...

  13. 49 CFR 1242.16 - Road property damaged-other (account XX-19-48).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 9 2013-10-01 2013-10-01 false Road property damaged-other (account XX-19-48... Structures § 1242.16 Road property damaged—other (account XX-19-48). Separate common expenses in proportion... accounts: Road Property Damaged—Running (XX-17-48) Road Property Damaged—Switching (XX-18-48) ...

  14. 49 CFR 1242.16 - Road property damaged-other (account XX-19-48).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Road property damaged-other (account XX-19-48... Structures § 1242.16 Road property damaged—other (account XX-19-48). Separate common expenses in proportion... accounts: Road Property Damaged—Running (XX-17-48) Road Property Damaged—Switching (XX-18-48) ...

  15. 49 CFR 1242.16 - Road property damaged-other (account XX-19-48).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Road property damaged-other (account XX-19-48... Structures § 1242.16 Road property damaged—other (account XX-19-48). Separate common expenses in proportion... accounts: Road Property Damaged—Running (XX-17-48) Road Property Damaged—Switching (XX-18-48) ...

  16. 49 CFR 1242.16 - Road property damaged-other (account XX-19-48).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Road property damaged-other (account XX-19-48... Structures § 1242.16 Road property damaged—other (account XX-19-48). Separate common expenses in proportion... accounts: Road Property Damaged—Running (XX-17-48) Road Property Damaged—Switching (XX-18-48) ...

  17. 49 CFR 1242.16 - Road property damaged-other (account XX-19-48).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Road property damaged-other (account XX-19-48... Structures § 1242.16 Road property damaged—other (account XX-19-48). Separate common expenses in proportion... accounts: Road Property Damaged—Running (XX-17-48) Road Property Damaged—Switching (XX-18-48) ...

  18. The genetics of XX gonadal dysgenesis

    SciTech Connect

    Aittomaeki, K. )

    1994-05-01

    In a nationwide population-based study of women born between 1950 and 1976, 75 patients with XX gonadal dysgenesis (XXGD) were identified in Finland. Patients were ascertained through hospital records and the registers of chromosome laboratories. In one family 4 daughters were affected; in six families 2 daughters were affected; and 57 cases were isolated. In one additional family the two affected females were in successive generations. Population records were utilized to trace ancestors of patients back to the beginning of the 19th century, in most cases. Consanguinity was detected in 8 (12%) of 66 families. When females only are considered, the segregation analyses yield a proportion of .23 affected. The relatively large number of affected individuals identified (incidence 1 in 8,300 live-born girls) implies a high gene frequency in the Finnish population. The geographic distribution was highly uneven, with most families originating in the sparsely populated north-central part of Finland. These findings support the existence of an autosomal recessive (XXGD) gene (locus designation [open quotes]ODG1[close quotes]) that is highly enriched in Finland. The multiplex families already identified will make it possible to map the ODG1 gene by a random search for linkage by using polymorphic markers. Linkage-disequilibrium analysis in the sporadic patients will then be used to test for genetic homogeneity versus heterogeneity. 27 refs., 3 figs.

  19. [Enteroviruses in the XX and XXI centuries].

    PubMed

    Seĭbil', V B; Malyshkina, L P

    2005-01-01

    The modern view of the role of enteroviruses in the eradication of poliomyelitis is presented. Enteroviruses were discovered in the XX century. In the 1950s they caused great epidemics of poliomyelitis and serous meningitis in many countries of the world. The introduction of oral poliomyelitis vaccine (OPV) into medical practice made it possible to eliminate the epidemics of poliomyelitis in a short time. Poliomyelitis morbidity was reduced to sporadic cases and in a number of regions disappeared. OPV produced non-specific influence also on the epidemics of serous meningitis, as well as on a case incidence. The eradication of poliomyelitis viruses and the cessation of immunization with OPV will not result in eradication of paralytic diseases. Paralytogenic viruses of 20 serotypes circulate in nature, and some of these viruses are capable of causing the outbreaks of severe paralytic diseases. The authors propose either to retain immunization with OVP as tour immunizations with monovaccine of type 2, or to create new live enterovirus vaccines on the basis of avirulent enterovirus strains.

  20. A healthy, female chimera with 46,XX/46,XY karyotype.

    PubMed

    Binkhorst, Mathijs; de Leeuw, Nicole; Otten, Barto J

    2009-01-01

    We report a healthy and unambiguously female newborn, whose phenotypic sex contradicted the expected male sex based on previously performed prenatal cytogenetic analysis. Both 46,XX and 46,XY cells were detected in a villus sample, the former having been attributed to maternal cell contamination. Postnatal karyotyping in peripheral lymphocytes confirmed the presence of two cell lines, one 46,XX (70%) and one 46,XY (30%). After exclusion of alternative explanations for the observed genotype, a diagnosis of chimerism was made. Chimeras containing cell lines of opposite sex usually feature ovotesticular development with associated genital ambiguity. To account for the normal female appearance of our patient, we postulate the exclusive involvement of 46,XX cells in gonad formation.

  1. 49 CFR 1242.14 - Administration-other (account XX-19-06).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Structures § 1242.14 Administration—other (account XX-19-06). Separate common administration—other expenses... accounts are separated between freight and passenger services: Administration: Track (XX-19-02) Bridges...

  2. 49 CFR 1242.14 - Administration-other (account XX-19-06).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Structures § 1242.14 Administration—other (account XX-19-06). Separate common administration—other expenses... accounts are separated between freight and passenger services: Administration: Track (XX-19-02) Bridges...

  3. 49 CFR 1242.14 - Administration-other (account XX-19-06).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Structures § 1242.14 Administration—other (account XX-19-06). Separate common administration—other expenses... accounts are separated between freight and passenger services: Administration: Track (XX-19-02) Bridges...

  4. 76 FR 57767 - Proposed Generic Communication; Draft NRC Generic Letter 2011-XX: Seismic Risk Evaluations for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-16

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Proposed Generic Communication; Draft NRC Generic Letter 2011-XX: Seismic Risk Evaluations for... NRC Generic Letter 2011- XX: Seismic Risk Evaluations for Operating Reactors. This action is...

  5. Using Title XX to Serve Children and Youth.

    ERIC Educational Resources Information Center

    Twiname, John D.; And Others

    With the passage in early 1975 of the social service amendments to the Social Security Act, referred to as Title XX, a major new opportunity to serve children and youth has emerged. Seizing the opportunity will be largely dependent on the well-prepared presentation of a case for the needs of young people by dedicated advocates in every state.…

  6. A comparative genomic hybridization study in a 46,XX male.

    PubMed

    Rigola, M Angels; Carrera, Marta; Ribas, Isabel; Egozcue, Josep; Miró, Rosa; Fuster, Carme

    2002-07-01

    To identify Y chromosome material in an azoospermic male with an XX karyotype. Case report. Faculty of medicine and Centro de Patologia Celular (CPC) medical center. A 33-year-old man with infertility. G-banding, fluorescence in situ hybridization (FISH), polymerase chain reaction (PCR), and comparative genomic hybridization (CGH). FISH for X and Y chromosomes, PCR for the SRYgene and amelogenin gene in the Xp (AMGX) and (AMGY), and losses or gains with CGH. FISH analysis using X and Y chromosome-specific probes showed an X chromosome containing Y chromosome sequences on the top of the short arm; this Y chromosome region was not visible by conventional cytogenetic analysis. PCR amplification of DNA showed the presence of the sex-determining region of the Y chromosome (SRY) and the amelogenin gene in the pseudoautosomal boundary of the X chromosome (AMGX). CGH confirmed the presence of the chromosome region Yp11.2-pter and detected the presence of the two otherwise normal X chromosomes. The two Xpter (XPAR1) pseudoautosomal regions present in this XX male suggest the need to reevaluate XX males using CGH and PCR to characterize the clinical variability in XX males due to genes other than those located on the Y chromosome.

  7. 30. XX byproducts building (containing coke gas compressors at north ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    30. XX by-products building (containing coke gas compressors at north end, ammonia stills in south end), #20 coal conveyor jutting out of top on east side, continuing out west side to bunker. Looking south/southeast - Rouge Steel Company, 3001 Miller Road, Dearborn, MI

  8. 29. Coke oven byproduct building "XX" with ammonia stills; powerhouse ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    29. Coke oven by-product building "XX" with ammonia stills; powerhouse with 8 sisters (stacks) in background; conveyor #20 (with break) on right, pulevrized coal storage bunker on left. Looking north/northwest - Rouge Steel Company, 3001 Miller Road, Dearborn, MI

  9. 49 CFR 1242.66 - Administration (account XX-52-01).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... OPERATING EXPENSES BETWEEN FREIGHT SERVICE AND PASSENGER SERVICE FOR RAILROADS 1 Operating Expenses... common expenses in the following accounts: Switch Cews (XX-52-64) Controlling Operations (XX-52-65) Yard and Terminal Clerical (XX-52-66) Operating Switches, Signals, Retarders and Humps...

  10. 49 CFR 1242.66 - Administration (account XX-52-01).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... OPERATING EXPENSES BETWEEN FREIGHT SERVICE AND PASSENGER SERVICE FOR RAILROADS 1 Operating Expenses... common expenses in the following accounts: Switch Cews (XX-52-64) Controlling Operations (XX-52-65) Yard and Terminal Clerical (XX-52-66) Operating Switches, Signals, Retarders and Humps...

  11. 75 FR 67165 - Proposed Collection; Comment Request for Revenue Procedure2007-XX (RP-155430-05)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-01

    ... Internal Revenue Service Proposed Collection; Comment Request for Revenue Procedure 2007- XX (RP-155430-05... Procedure 2007-XX (RP-155430-05), Section 6707/6707A Accelerated Appeals Procedure. DATES: Written comments... Number: 1545-2094. Revenue Procedure Number: Revenue Procedure 2007-XX (RP-155430-05). Abstract: The...

  12. Title XX: Social Services in Your State. A Child Advocate's Handbook for Action.

    ERIC Educational Resources Information Center

    Children's Defense Fund, Washington, DC.

    This booklet is a guide for those wishing to route Title XX money into the community programs for children. Part I discusses ways for child advocates to participate in four key stages of the Title XX planning process in their state: planning proposals, raising the 25% non-federal share of the funds required by Title XX, and publishing proposed and…

  13. Fate of the uterus in 46XX cloacal exstrophy patients.

    PubMed

    Naiditch, Jessica A; Radhakrishnan, Jayant; Chin, Anthony C; Cheng, Earl; Yerkes, Elizabeth; Reynolds, Marleta

    2013-10-01

    Genetically female cloacal exstrophy (46XX CE) patients develop complications later in life due to their abnormal uterine anatomy, resulting in various invasive gynecologic procedures. Furthermore, they have difficulty becoming pregnant, and if they do conceive, they are unlikely to carry the pregnancy to term. We performed this review to determine the rate of gynecological complications, the fate of the uterus, and the rate of pregnancy in 46XX cloacal exstrophy patients. All charts for 46XX CE patients treated by us were reviewed following IRB approval. Patient age at last follow-up, surgical management of the uterus, uterine complications, and pregnancies were recorded. The charts of all 16 of our 46XX CE patients who survived past the neonatal period were reviewed. Two patients underwent hemi-hysterectomy (HH): 1 for an atretic hemi-uterus at birth, another for abnormal uterine insertion at 3 years. A third patient initially had HH for hydrometrocolpos leading to ureteral and colonic obstruction at 14 years but she required a completion hysterectomy a year later. Four patients underwent total hysterectomy (TH) at the outset: 2 neonates for a diminutive uterus with extreme disparity in the halves, another for uterine prolapse at 1 month of age, and a fourth for hematometrocolpos at 16 years of age. Six patients reached adulthood without requiring gynecologic intervention; one of these six is now being managed at another institution. Two patients are prepubertal and one was lost to follow-up. The only patient in the series who became pregnant miscarried at 11 weeks gestation. Out of 13 post-pubertal patients 6 have retained the entire uterus and another 2 had a hemi-hysterectomy. One patient who became pregnant miscarried at 11 weeks gestation. We believe it is appropriate to avoid ablative genital surgery as far as possible and for these patients to become pregnant after detailed discussion with physicians experienced in the care of 46XX CE patients. Copyright

  14. 8- to 13-micron spectroscopy of Comet Levy 1990 XX

    NASA Technical Reports Server (NTRS)

    Lynch, David K.; Russell, Ray W.; Hackwell, John A.; Hanner, Martha S.; Hammel, Heidi B.

    1992-01-01

    The results are reported of IR spectroscopy of Comet Levy 1990 XX over a three-day period when the comet was about 1.54 AU from the sun roughly 70 days before perihelion. Comet Levy 1990 XX was bright, and for at least part of its inbound journey toward perihelion, active. At a distance of 1.54 AU from the sun it showed strong structured silicate emission with peaks or shoulders at 9.8 and 11.2 microns. These features resemble those of Comets P/Halley and Bradfield 1987 XXIX. The comet was variable in brightness. Specifically, the contrast of the silicate features changed by a factor of two relative to the continuum level and showed some evidence for a shape change as well.

  15. Sry-negative XX true hermaphroditism in a roe deer.

    PubMed

    Pajares, G; Balseiro, A; Pérez-Pardal, L; Gamarra, J A; Monteagudo, L V; Goyache, F; Royo, L J

    2009-05-01

    A two-year-old roe deer was brought down in the course of a hunt in the north of Spain (Asturias). On physical examination the individual presented well-developed bared antlers, but surprisingly a female external genitalia. Several anatomical, histological and genetic analyses were performed in order to explain the observed phenotype. Necropsy evidenced ovary-like structures with follicles on the surface; histological analyses of testes evidenced positive immunolabel against testosterone in Leydig cells; genetic analyses showed that the sex of the individual was consistent with a female individual. PCR analysis failed to detect SRY sequences; no PIS deletion, which is responsible for XX sex-reversal in goats, was detected. On the basis of its presumptive normal female sexual karyotype (XX) and the presence of two functional abdominal bilateral testes and ovaries, the roe deer was finally diagnosed as possessing an XX hermaphroditism syndrome. However, as in many other cases, the specific reason for the occurrence of this case of hermaphroditism could not be determined.

  16. 49 CFR 1242.28 - Roadway machines, small tools and supplies, and snow removal (accounts XX-19-36 to XX-19-38...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 9 2013-10-01 2013-10-01 false Roadway machines, small tools and supplies, and snow removal (accounts XX-19-36 to XX-19-38, inclusive). 1242.28 Section 1242.28 Transportation Other... PASSENGER SERVICE FOR RAILROADS 1 Operating Expenses-Way and Structures § 1242.28 Roadway machines,...

  17. 49 CFR 1242.28 - Roadway machines, small tools and supplies, and snow removal (accounts XX-19-36 to XX-19-38...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Roadway machines, small tools and supplies, and snow removal (accounts XX-19-36 to XX-19-38, inclusive). 1242.28 Section 1242.28 Transportation Other... PASSENGER SERVICE FOR RAILROADS 1 Operating Expenses-Way and Structures § 1242.28 Roadway machines,...

  18. 49 CFR 1242.28 - Roadway machines, small tools and supplies, and snow removal (accounts XX-19-36 to XX-19-38...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Roadway machines, small tools and supplies, and snow removal (accounts XX-19-36 to XX-19-38, inclusive). 1242.28 Section 1242.28 Transportation Other... PASSENGER SERVICE FOR RAILROADS 1 Operating Expenses-Way and Structures § 1242.28 Roadway machines,...

  19. 49 CFR 1242.28 - Roadway machines, small tools and supplies, and snow removal (accounts XX-19-36 to XX-19-38...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Roadway machines, small tools and supplies, and snow removal (accounts XX-19-36 to XX-19-38, inclusive). 1242.28 Section 1242.28 Transportation Other... PASSENGER SERVICE FOR RAILROADS 1 Operating Expenses-Way and Structures § 1242.28 Roadway machines,...

  20. 49 CFR 1242.28 - Roadway machines, small tools and supplies, and snow removal (accounts XX-19-36 to XX-19-38...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Roadway machines, small tools and supplies, and snow removal (accounts XX-19-36 to XX-19-38, inclusive). 1242.28 Section 1242.28 Transportation Other... PASSENGER SERVICE FOR RAILROADS 1 Operating Expenses-Way and Structures § 1242.28 Roadway machines,...

  1. Services Officer Utilization Field (AFS 62XX and Equivalent-Grade Civilians).

    DTIC Science & Technology

    1986-06-01

    CHART le~ -- Sq ,.. O. pt’*. q UNITED STATES AIR FORCE cv, Lfl o D SERVICES OFFICER UTILIZATION FIELD (AFS 62XX AND EQUIVALENT-GRADE CIVILLANS) AFPT 90...Administration From January through Ma’ch 1985, job inventories were administered to all elicible AFSC 62XX nfficer: in the continental United States ... PUBLIC RELEASE: DISTRIBUTION UNLIMITED t, , . . . .. .. . . . . , . . . . . . , . _". ... , I! . . $ IJSTRIBIJTION FOR AFS( u-)XX OSR AND SUPPORTING

  2. First Annual Report to Congress on Title XX of the Social Security Act.

    ERIC Educational Resources Information Center

    Department of Health, Education, and Welfare, Washington, DC.

    This annual report to Congress on Title XX of the Social Security Act reports on the operation of the 1976 fiscal year program. Preceding the report are descriptive highlights of the program. Title XX of the Social Security Act changes the role and relationships of the Department of Health, Education, and Welfare; the individual states; and…

  3. 49 CFR 1242.22 - Shop buildings-locomotives (account XX-19-24).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Shop buildings-locomotives (account XX-19-24). 1242.22 Section 1242.22 Transportation Other Regulations Relating to Transportation (Continued) SURFACE... Structures § 1242.22 Shop buildings—locomotives (account XX-19-24). Separate common expenses according...

  4. 49 CFR 1242.22 - Shop buildings-locomotives (account XX-19-24).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Shop buildings-locomotives (account XX-19-24). 1242.22 Section 1242.22 Transportation Other Regulations Relating to Transportation (Continued) SURFACE... Structures § 1242.22 Shop buildings—locomotives (account XX-19-24). Separate common expenses according...

  5. 49 CFR 1242.24 - Shop buildings-other equipment (account XX-19-26).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Shop buildings-other equipment (account XX-19-26). 1242.24 Section 1242.24 Transportation Other Regulations Relating to Transportation (Continued) SURFACE... Structures § 1242.24 Shop buildings—other equipment (account XX-19-26). Assign directly to freight (or as...

  6. 49 CFR 1242.25 - Locomotive servicing facilities (account XX-19-27).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Locomotive servicing facilities (account XX-19-27). 1242.25 Section 1242.25 Transportation Other Regulations Relating to Transportation (Continued) SURFACE... Structures § 1242.25 Locomotive servicing facilities (account XX-19-27). Separate common expenses according...

  7. 49 CFR 1242.49 - Equipment damaged (account XX-27-48).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Equipment damaged (account XX-27-48). 1242.49...-Equipment § 1242.49 Equipment damaged (account XX-27-48). Separate common expenses according to distribution of common expenses in machinery, passenger and other revenue equipment, computer and data processing...

  8. 49 CFR 1242.45 - Passenger and other revenue equipment (account XX-27-45).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Passenger and other revenue equipment (account XX-27-45). 1242.45 Section 1242.45 Transportation Other Regulations Relating to Transportation... RAILROADS 1 Operating Expenses-Equipment § 1242.45 Passenger and other revenue equipment (account XX-27-45...

  9. 49 CFR 1242.11 - Administration-bridges and buildings (account XX-19-03).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Administration-bridges and buildings (account XX... RAILROADS 1 Operating Expenses-Way and Structures § 1242.11 Administration—bridges and buildings (account XX-19-03). Separate common administration—bridges and buildings expenses between freight and passenger...

  10. 49 CFR 1242.11 - Administration-bridges and buildings (account XX-19-03).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Administration-bridges and buildings (account XX... RAILROADS 1 Operating Expenses-Way and Structures § 1242.11 Administration—bridges and buildings (account XX-19-03). Separate common administration—bridges and buildings expenses between freight and passenger...

  11. 49 CFR 1242.11 - Administration-bridges and buildings (account XX-19-03).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Administration-bridges and buildings (account XX... RAILROADS 1 Operating Expenses-Way and Structures § 1242.11 Administration—bridges and buildings (account XX-19-03). Separate common administration—bridges and buildings expenses between freight and passenger...

  12. 49 CFR 1242.11 - Administration-bridges and buildings (account XX-19-03).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 9 2013-10-01 2013-10-01 false Administration-bridges and buildings (account XX... RAILROADS 1 Operating Expenses-Way and Structures § 1242.11 Administration—bridges and buildings (account XX-19-03). Separate common administration—bridges and buildings expenses between freight and passenger...

  13. 49 CFR 1242.11 - Administration-bridges and buildings (account XX-19-03).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Administration-bridges and buildings (account XX... RAILROADS 1 Operating Expenses-Way and Structures § 1242.11 Administration—bridges and buildings (account XX-19-03). Separate common administration—bridges and buildings expenses between freight and passenger...

  14. 49 CFR 1242.22 - Shop buildings-locomotives (account XX-19-24).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Shop buildings-locomotives (account XX-19-24). 1242.22 Section 1242.22 Transportation Other Regulations Relating to Transportation (Continued) SURFACE... Structures § 1242.22 Shop buildings—locomotives (account XX-19-24). Separate common expenses according to...

  15. 49 CFR 1242.22 - Shop buildings-locomotives (account XX-19-24).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Shop buildings-locomotives (account XX-19-24). 1242.22 Section 1242.22 Transportation Other Regulations Relating to Transportation (Continued) SURFACE... Structures § 1242.22 Shop buildings—locomotives (account XX-19-24). Separate common expenses according to...

  16. 49 CFR 1242.22 - Shop buildings-locomotives (account XX-19-24).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 9 2013-10-01 2013-10-01 false Shop buildings-locomotives (account XX-19-24). 1242.22 Section 1242.22 Transportation Other Regulations Relating to Transportation (Continued) SURFACE... Structures § 1242.22 Shop buildings—locomotives (account XX-19-24). Separate common expenses according to...

  17. 49 CFR 1242.46 - Computers and data processing equipment (account XX-27-46).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Computers and data processing equipment (account XX-27-46). 1242.46 Section 1242.46 Transportation Other Regulations Relating to Transportation... RAILROADS 1 Operating Expenses-Equipment § 1242.46 Computers and data processing equipment (account XX-27-46...

  18. 49 CFR 1242.46 - Computers and data processing equipment (account XX-27-46).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Computers and data processing equipment (account XX-27-46). 1242.46 Section 1242.46 Transportation Other Regulations Relating to Transportation... RAILROADS 1 Operating Expenses-Equipment § 1242.46 Computers and data processing equipment (account XX-27-46...

  19. 49 CFR 1242.46 - Computers and data processing equipment (account XX-27-46).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Computers and data processing equipment (account XX-27-46). 1242.46 Section 1242.46 Transportation Other Regulations Relating to Transportation... RAILROADS 1 Operating Expenses-Equipment § 1242.46 Computers and data processing equipment (account XX-27-46...

  20. 49 CFR 1242.46 - Computers and data processing equipment (account XX-27-46).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Computers and data processing equipment (account XX-27-46). 1242.46 Section 1242.46 Transportation Other Regulations Relating to Transportation... RAILROADS 1 Operating Expenses-Equipment § 1242.46 Computers and data processing equipment (account XX-27-46...

  1. 49 CFR 1242.46 - Computers and data processing equipment (account XX-27-46).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 9 2013-10-01 2013-10-01 false Computers and data processing equipment (account XX-27-46). 1242.46 Section 1242.46 Transportation Other Regulations Relating to Transportation... RAILROADS 1 Operating Expenses-Equipment § 1242.46 Computers and data processing equipment (account XX-27-46...

  2. 49 CFR 1242.59 - Train inspection and lubrication (account XX-51-62).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Train inspection and lubrication (account XX-51-62). 1242.59 Section 1242.59 Transportation Other Regulations Relating to Transportation (Continued) SURFACE...-Transportation § 1242.59 Train inspection and lubrication (account XX-51-62). Separate common expenses on...

  3. 49 CFR 1242.23 - Shop buildings-freight cars (account XX-13-25).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 9 2013-10-01 2013-10-01 false Shop buildings-freight cars (account XX-13-25). 1242.23 Section 1242.23 Transportation Other Regulations Relating to Transportation (Continued) SURFACE... Structures § 1242.23 Shop buildings—freight cars (account XX-13-25). These accounts pertain solely to...

  4. 49 CFR 1242.86 - Industrial development (account XX-61-90).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Industrial development (account XX-61-90). 1242.86 Section 1242.86 Transportation Other Regulations Relating to Transportation (Continued) SURFACE....86 Industrial development (account XX-61-90). These accounts pertain solely to freight service...

  5. 49 CFR 1242.86 - Industrial development (account XX-61-90).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Industrial development (account XX-61-90). 1242.86 Section 1242.86 Transportation Other Regulations Relating to Transportation (Continued) SURFACE....86 Industrial development (account XX-61-90). These accounts pertain solely to freight service...

  6. 49 CFR 1242.57 - Dispatching trains (account XX-51-58).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Dispatching trains (account XX-51-58). 1242.57 Section 1242.57 Transportation Other Regulations Relating to Transportation (Continued) SURFACE...-Transportation § 1242.57 Dispatching trains (account XX-51-58). Separate common expenses on the basis of...

  7. 49 CFR 1242.57 - Dispatching trains (account XX-51-58).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 9 2013-10-01 2013-10-01 false Dispatching trains (account XX-51-58). 1242.57 Section 1242.57 Transportation Other Regulations Relating to Transportation (Continued) SURFACE...-Transportation § 1242.57 Dispatching trains (account XX-51-58). Separate common expenses on the basis of...

  8. 49 CFR 1242.57 - Dispatching trains (account XX-51-58).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Dispatching trains (account XX-51-58). 1242.57 Section 1242.57 Transportation Other Regulations Relating to Transportation (Continued) SURFACE...-Transportation § 1242.57 Dispatching trains (account XX-51-58). Separate common expenses on the basis of...

  9. 49 CFR 1242.57 - Dispatching trains (account XX-51-58).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Dispatching trains (account XX-51-58). 1242.57 Section 1242.57 Transportation Other Regulations Relating to Transportation (Continued) SURFACE...-Transportation § 1242.57 Dispatching trains (account XX-51-58). Separate common expenses on the basis of...

  10. 49 CFR 1242.23 - Shop buildings-freight cars (account XX-13-25).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Shop buildings-freight cars (account XX-13-25). 1242.23 Section 1242.23 Transportation Other Regulations Relating to Transportation (Continued) SURFACE... Structures § 1242.23 Shop buildings—freight cars (account XX-13-25). These accounts pertain solely to...

  11. 49 CFR 1242.23 - Shop buildings-freight cars (account XX-13-25).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Shop buildings-freight cars (account XX-13-25). 1242.23 Section 1242.23 Transportation Other Regulations Relating to Transportation (Continued) SURFACE... Structures § 1242.23 Shop buildings—freight cars (account XX-13-25). These accounts pertain solely to...

  12. 49 CFR 1242.23 - Shop buildings-freight cars (account XX-13-25).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Shop buildings-freight cars (account XX-13-25). 1242.23 Section 1242.23 Transportation Other Regulations Relating to Transportation (Continued) SURFACE... Structures § 1242.23 Shop buildings—freight cars (account XX-13-25). These accounts pertain solely to...

  13. 49 CFR 1242.23 - Shop buildings-freight cars (account XX-13-25).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Shop buildings-freight cars (account XX-13-25). 1242.23 Section 1242.23 Transportation Other Regulations Relating to Transportation (Continued) SURFACE... Structures § 1242.23 Shop buildings—freight cars (account XX-13-25). These accounts pertain solely to...

  14. 49 CFR 1242.10 - Administration-track (account XX-19-02).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... accounts are separated between freight and passenger services: Roadway: Running (XX-17-10) Switching (XX-18-10) Ties: Running (21-17-13) Switching (21-18-13) Rails: Running (21-17-14) Switching (21-18-14) Other Track Materials: Running (21-17-15) Switching (21-18-15) Ballast: Running (21-17-16) Switching (21...

  15. 49 CFR 1242.10 - Administration-track (account XX-19-02).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... accounts are separated between freight and passenger services: Roadway: Running (XX-17-10) Switching (XX-18-10) Ties: Running (21-17-13) Switching (21-18-13) Rails: Running (21-17-14) Switching (21-18-14) Other Track Materials: Running (21-17-15) Switching (21-18-15) Ballast: Running (21-17-16) Switching (21...

  16. Next generation 9xx/10xx nm high power laser diode bars for multi-kilowatt industrial applications

    NASA Astrophysics Data System (ADS)

    Commin, Paul; Todt, René; Krejci, Martin; Bättig, Rainer; Brunner, Reinhard; Lichtenstein, Norbert

    2013-02-01

    We report on the development of high power, 9xx-10xx nm laser diode bars for use in direct diode systems and for solidstate and fibre laser pumping with applications in industrial markets. For 1 cm wide bars on micro channel cooler (MCC) we have achieved a reliable output power of 250 W across the 900 nm - 1060 nm range. At this output power level we have achieved power conversion efficiencies of 65-66 % and 90 % power content slow axis beam divergence of ~6.5°. Results of a 6400 h life test show an average power degradation of 0.6 % per 1000 h at this operating power level. We will also show results of high power bars assembled on the new OCLARO conductive cooler, the BLM. This new cooler has a small footprint of 12.6 mm × 24.8 mm and is designed for lateral or vertical stacking of diodes in multi kilowatt systems but with the benefits associated with a conductive cooler. The thermal properties are shown to be the same as for a standard CS mount. 1 cm wide high fill factor bars and 0.5 cm wide low fill factor half bars assembled on the BLM operate at 63-64 % power conversion efficiency (PCE) with output powers of up to 250 W and 150 W, respectively.

  17. Two males with SRY-positive 46,XX testicular disorder of sex development.

    PubMed

    Gunes, Sezgin; Asci, Ramazan; Okten, Gülsen; Atac, Fatih; Onat, Onur E; Ogur, Gonul; Aydin, Oguz; Ozcelik, Tayfun; Bagci, Hasan

    2013-02-01

    The 46,XX testicular disorder of sex development (46,XX testicular DSD) is a rare phenotype associated with disorder of the sex chromosomes. We describe the clinical, molecular, and cytogenetic findings of a 16- and a 30-year-old male patient with sex-determining region Y (SRY)-positive 46,XX testicular DSD. Chromosomal analysis revealed 46,XX karyotype. Fluorescence in situ hybridization (FISH) showed the SRY region translocated to the short arm of the X chromosome. The presence of the SRY gene was also confirmed by polymerase chain reaction (PCR). The X chromosome inactivation (XCI) assay showed that both patients have a random pattern of X chromosome inactivation. This report compares the symptoms and features of the SRY-positive 46,XX testicular DSD patients.

  18. FAST20XX: Achievements On European Suborbital Space Flight

    NASA Astrophysics Data System (ADS)

    Mack, A.; Steelant, J.; Adirim, H.; Lentsch, A.; Marini, M.; Pilz, N.

    2011-05-01

    In Europe, the EC co-funded project FAST20XX aims at exploring the borderline between aviation and space by investigating suborbital vehicles. The main focus is the identification and mastering of critical technologies for such vehicles rather than the vehicle development itself. Besides the objectives and overall layout of the project, the paper addresses also the progress made during the first period of the project. Two vehicle concepts are considered. A first one is a space vehicle launched from an airplane providing a low-energy ballistic flight experience using hybrid propulsion. The second is a vertically starting two-stage rocket space vehicle system concept taken as a basis to identify the conditions and constraints experienced during high- energy suborbital ultra-fast transport. The paper mainly discusses the two actual reference vehicles and the technical aspects of prerequisites for commercial operation including safety, human spaceflight, business cases, environmental and legal issues.

  19. The chemical composition of R Coronae Borealis and XX Camelopardalis

    NASA Astrophysics Data System (ADS)

    Cottrell, P. L.; Lambert, D. L.

    1982-10-01

    The R Coronae Borealis stars R CrB and XX Cam are examined using extensive high-resolution Reticon data. Effective temperatures, values of log g, microturbulent velocities, and C/He values are determined, along with elemental abundances and abundance ratios for a wide range of species, including the light and heavy s-process elements. Helium- and carbon-rich models are employed, as is an appropriate model atmosphere code. The evolutionary history of R CrB stars is discussed in detail. It is concluded that both CNO cycle and 3-alpha processed material must have been mixed into the observable layers. The He core and He shell flashes are suggested as possible triggers for the mixing and for the extensive mass loss required to expose the heavily processed layers.

  20. Blockage of progestin physiology disrupts ovarian differentiation in XX Nile tilapia (Oreochromis niloticus)

    SciTech Connect

    Zhou, Linyan; Luo, Feng; Fang, Xuelian; Charkraborty, Tapas; Wu, Limin; Wei, Jing; Wang, Deshou

    2016-04-22

    Previous studies indicated that maturation inducing hormone, 17α, 20β-Dihydroxy-4-pregnen-3-one (DHP), probably through nuclear progestin receptor (Pgr), might be involved in spermatogenesis and oogenesis in fish. To further elucidate DHP actions in teleostean ovarian differentiation, we analyzed the expression of pgr in the ovary of Nile tilapia (Oreochromis niloticus), and performed RU486 (a synthetic Pgr antagonist) treatment in XX fish from 5 days after hatching (dah) to 120dah. Tilapia Pgr was abundantly expressed in the follicular cells surrounding oocytes at 30 and 90dah. Continuous RU486 treatment led to the blockage of oogenesis and masculinization of somatic cells in XX fish. Termination of RU486 treatment and maintenance in normal condition resulted in testicular differentiation, and estrogen compensation in RU486-treated XX fish successfully restored oogenesis. In RU486-treated XX fish, transcript levels of female dominant genes were significantly reduced, while male-biased genes were evidently augmented. Meanwhile, both germ cell mitotic and meiotic markers were substantially reduced. Consistently, estrogen production levels were significantly declined in RU486-treated XX fish. Taken together, our data further proved that DHP, possibly through Pgr, might be essential in the ovarian differentiation and estrogen production in fish. - Highlights: • DHP plays a critical role in early stage oogenesis of XX tilapia. • Blockage of DHP actions by RU486 treatment led to masculinization and/or sex reversal in XX tilapia. • Both DHP and estrogen are indispensable for ovarian differentiation.

  1. Performance and reliability of high power 7xx nm laser diodes

    NASA Astrophysics Data System (ADS)

    Bao, Ling; Wang, Jun; Devito, Mark; Xu, Dapeng; Grimshaw, Mike; Dong, Weimin; Guan, Xingguo; Huang, Hua; Leisher, Paul; Zhang, Shiguo; Wise, Damian; Martinsen, Robert; Haden, Jim

    2011-02-01

    High power diode lasers in 7xx-nm region, have been needed for various applications. Compared to 9xx nm lasers that have been developed extensively in the last 20 years, high power lasers at 7xx-nm region presents much more challenges for operation power, efficiency, temperature performance and reliability. This paper will present recent progresses on 7xx nm laser diodes for the above attributes. Two laser designs will be reviewed and high power diode laser performance and reliability will be presented. Single emitter devices, with 200μm wide emitting width, show up to 10W reliable operation power, with peak efficiency more than 65%. Accelerated life testing at 12A, 50°C heatsink temperature has been running for thousands of hours. High temperature performance and high COMD threshold (> 20W) will also be shown. Life-test failure modes will also be discussed. In summary, with advanced epitaxial structure design and MOCVD process, critical facet passivation and advanced heatsink and bonding technology, 7xx-8xx nm devices have been demonstrated with high performance and reliability similar to those of 9xx nm devices.

  2. Differential lactate and cholesterol synthetic activities in XY and XX Sertoli cells

    PubMed Central

    Shishido, Yurina; Baba, Takashi; Sato, Tetsuya; Shima, Yuichi; Miyabayashi, Kanako; Inoue, Miki; Akiyama, Haruhiko; Kimura, Hiroshi; Kanai, Yoshiakira; Ishihara, Yasuhiro; Haraguchi, Shogo; Miyazaki, Akira; Rozman, Damjana; Yamazaki, Takeshi; Choi, Man-Ho; Ohkawa, Yasuyuki; Suyama, Mikita; Morohashi, Ken-ichirou

    2017-01-01

    SRY, a sex-determining gene, induces testis development in chromosomally female (XX) individuals. However, mouse XX Sertoli cells carrying Sry (XX/Sry Sertoli cells) are incapable of fully supporting germ cell development, even when the karyotype of the germ cells is XY. While it has therefore been assumed that XX/Sry Sertoli cells are not functionally equivalent to XY Sertoli cells, it has remained unclear which specific functions are affected. To elucidate the functional difference, we compared the gene expression of XY and XX/Sry Sertoli cells. Lactate and cholesterol metabolisms, essential for nursing the developing germ cells, were down-regulated in XX/Sry cells, which appears to be caused at least in part by the differential expression of histone modification enzymes SMCX/SMCY (H3K4me3 demethylase) and UTX/UTY (H3K27me3 demethylase) encoded by the sex chromosomes. We suggest that down-regulation of lactate and cholesterol metabolism that may be due to altered epigenetic modification affects the nursing functions of XX/Sry Sertoli cells. PMID:28150810

  3. Aggressive and mating behaviors in two types of sex reversed mice: XY females and XX males.

    PubMed

    Canastar, Andrew; Maxson, Stephen C; Bishop, Colin E

    2008-02-01

    Aggressive and mating behaviors were assessed in XX females, XY females, and XY males of the C57BL/6/J/Ei ("C57BL/6" or "B6") strain of mouse. The Y chromosome of the XY females derives from Mus domesticus poschiavinus and the Y chromosome of the XY males derives from Mus musculus. The poschiavinus Y in the C57BL/6 background results in XY mice with either ovaries or ovotestes. Only those with ovaries were tested. These XY females appear to be endocrinologically identical to XX females. Aggressive and mating behaviors were also tested in XX males and XY males of the FVB/NtacfBR Odsex ("FVB") strain of mouse. The XX males have a transgene inserted 1 Mb upstream of the SOX9 gene, resulting in gonadal differentiation as a testis in the absence of a Y chromosome. C57BL/6 mice were tested for aggression in an instigated resident intruder paradigm and FVB/NtacfBR Odsex mice were tested for aggression in a neutral cage paradigm. Mice of both strains were tested with opponents of the same sex chromosome complement and gonadal sex. On the C57BL/6 background, the XY males were more aggressive than the XY and XX females, but there was no significant difference between the XX and XY females in aggression. On the FVB background, the XY and XX males were equally aggressive. Mice from both C57BL/6 and FVB backgrounds were tested for mating behaviors with females in hormonal estrus. On the C57BL/6 background, the XY males mounted more than the XY females, but there was no significant difference between the XY and XX females in mounting. On the FVB background, mounting, intromissions, and ejaculations were the same in XY and XX males. The implications of these findings for the effect of sex chromosome complement on sex differences in aggression and mating in mice are discussed.

  4. Isodicentric Y Mosaicism Involving a 46, XX Cell Line: Implications for Management

    PubMed Central

    Hipp, Lauren E.; Mohnach, Lauren; Wei, Sainan; Thomas, Inas H.; Elhassan, Maha; Sandberg, David E.; Quint, Elisabeth H.; Keegan, Catherine E.

    2016-01-01

    Carriers of isodicentric Y (idicY) mosaicism exhibit a wide range of clinical features, including short stature, gonadal abnormalities, and external genital anomalies. However, the phenotypic spectrum for individuals carrying an idicY and a 46, XX cell line is less clearly defined. A more complete description of the phenotype related to idicY is thus essential to guide management related to pubertal development, fertility, and gonadoblastoma risk in mosaic carriers. Findings from the evaluation of twin females with an abnormal karyotype, 48, XX, +idic(Yq)x2/47, XX, +idic(Yq)/46, XX, are presented to highlight the importance of interdisciplinary care in the management of multifaceted disorders of sex development. PMID:26407917

  5. 49 CFR 1242.18 - Communication systems (account XX-19-20).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Structures § 1242.18 Communication systems (account XX-19-20). Separate common expenses on the basis of the common expense separation in: Way and Structures—Administration—Track, Bridges and Culverts, and...

  6. 49 CFR 1242.18 - Communication systems (account XX-19-20).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Structures § 1242.18 Communication systems (account XX-19-20). Separate common expenses on the basis of the common expense separation in: Way and Structures—Administration—Track, Bridges and Culverts, and...

  7. 49 CFR 1242.18 - Communication systems (account XX-19-20).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Structures § 1242.18 Communication systems (account XX-19-20). Separate common expenses on the basis of the common expense separation in: Way and Structures—Administration—Track, Bridges and Culverts, and...

  8. Entanglement across extended random defects in the XX spin chain

    NASA Astrophysics Data System (ADS)

    Juhász, Róbert

    2017-08-01

    We study the half-chain entanglement entropy in the ground state of the spin-1/2 XX chain across an extended random defect, where the strength of disorder decays with the distance from the interface algebraically as Δ_l∼ l-κ . In the whole regime κ≥slant 0 , the average entanglement entropy is found to increase logarithmically with the system size L as S_L≃\\frac{c_eff(κ)}{6}\\ln L+const , where the effective central charge c_eff(κ) depends on κ. In the regime κ<1/2 , where the extended defect is a relevant perturbation, the strong-disorder renormalization group method gives c_eff(κ)=(1-2κ)\\ln2 , while, in the regime κ≥slant 1/2 , where the extended defect is irrelevant in the bulk, numerical results indicate a non-zero effective central charge, which increases with κ. The variation of c_eff(κ) is thus found to be non-monotonic and discontinuous at κ=1/2 .

  9. Thermodynamics of a dilute XX chain in a field

    SciTech Connect

    Timonin, P. N.

    2016-06-15

    Gapless phases in ground states of low-dimensional quantum spin systems are rather ubiquitous. Their peculiarity is a remarkable sensitivity to external perturbations due to permanent criticality of such phases manifested by a slow (power-low) decay of pair correlations and the divergence of the corresponding susceptibility. A strong influence of various defects on the properties of the system in such a phase can then be expected. Here, we consider the influence of vacancies on the thermodynamics of the simplest quantum model with a gapless phase, the isotropic spin-1/2 XX chain. The existence of the exact solution of this model gives a unique opportunity to describe in detail the dramatic effect of dilution on the gapless phase—the appearance of an infinite series of quantum phase transitions resulting from level crossing under the variation of a longitudinal magnetic field. We calculate the jumps in the field dependences of the ground-state longitudinal magnetization, susceptibility, entropy, and specific heat appearing at these transitions and show that they result in a highly nonlinear temperature dependence of these parameters at low T. Also, the effect of enhancement of the magnetization and longitudinal correlations in the dilute chain is established. The changes of the pair spin correlators under dilution are also analyzed. The universality of the mechanism of the quantum transition generation suggests that similar effects of dilution can also be expected in gapless phases of other low-dimensional quantum spin systems.

  10. Inverse participation ratios in the XX spin chain

    NASA Astrophysics Data System (ADS)

    Tsukerman, Emmanuel

    2017-03-01

    We continue the study of the inverse participation ratios (IPRs) of the XXZ Heisenberg spin chain initiated by Stéphan, Furukawa, Misguich, and Pasquier (2009) and continued by Misguich, Pasquier, and Luck (2016) by focusing on the case of the XX Heisenberg spin chain. For the ground state, Stéphan et al. note that calculating the IPR is equivalent to Dyson's constant term ex-conjecture. We express the IPRs of excited states as an apparently new "discrete" Hall inner product. We analyze this inner product using the theory of symmetric functions (Jack polynomials, Schur polynomials, the standard Hall inner product, and ωq ,t) to determine some exact expressions and asymptotics for IPRs. We show that IPRs can be indexed by partitions, and asymptotically the IPR of a partition is equal to that of the conjugate partition. We relate the IPRs to two other models from physics, namely, the circular symplectic ensemble of Dyson and the Dyson-Gaudin two-dimensional Coulomb lattice gas. Finally, we provide a description of the IPRs in terms of a signed count of diagonals of permutohedra.

  11. Population pharmacokinetics of ticagrelor and AR-C124910XX in patients with prior myocardial infarction
.

    PubMed

    Röshammar, Daniel; Bergstrand, Martin; Andersson, Tomas; Storey, Robert F; Hamrén, Bengt

    2017-05-01

    The population pharmacokinetics of ticagrelor and its active metabolite AR-C124910XX were characterized following ticagrelor 60 mg or 90 mg twice daily oral long-term treatment in 4,426 patients with a history of myocardial infarction. The ticagrelor and AR-C124910XX plasma concentration-time data were described by one-compartment models with first-order absorption or metabolite formation and elimination. Systemic exposure to ticagrelor and AR-C124910XX were stable over time. Ticagrelor apparent clearance (CL/F) was 17 L/h for the 60-mg and 15.4 L/h for the 90-mg dose. The CL/F of AR-C124910XX was 11.1 L/h for the 60-mg and 9.95 L/h for the 90-mg dose. Both ticagrelor and AR-C124910XX CL/F were independently influenced by body weight, sex, age, smoking, and Japanese ethnicity. Female sex and age > 75 years were the only categorical covariates, having more than 20% effect on AR-C124910XX CL/F. Ticagrelor CL/F was 6% higher and 11% lower, whereas AR-C124910XX CL/F was 26% higher and 34% lower for patients weighing 110 and 50 kg, respectively, compared with an 83 kg patient. The small differences in exposure to both ticagrelor and AR-C124910XX between demographic subgroups were in accordance with the consistent efficacy and safety outcomes observed across the population. The results were similar to those observed previously in patients with acute coronary syndromes.
.

  12. Cytogenetic analysis of somatic and germinal cells from 38,XX/38,XY phenotypically normal boars.

    PubMed

    Barasc, Harmonie; Ferchaud, Stéphane; Mary, Nicolas; Cucchi, Marie Adélaïde; Lucena, Amalia Naranjo; Letron, Isabelle Raymond; Calgaro, Anne; Bonnet, Nathalie; Dudez, Anne Marie; Yerle, Martine; Ducos, Alain; Pinton, Alain

    2014-01-15

    Many chromosomal abnormalities have been reported to date in pigs. Most of them have been balanced structural rearrangements, especially reciprocal translocations. A few cases of XY/XX chimerism have also been diagnosed within the national systematic chromosomal control program of young purebred boars carried out in France. Until now, this kind of chromosomal abnormality has been mainly reported in intersex individuals. We investigated 38,XY/38,XX boars presenting apparently normal phenotypes to evaluate the potential effects of this particular chromosomal constitution on their reproductive performance. To do this, we analyzed (1) the chromosomal constitution of cells from different organs in one boar; (2) the aneuploidy rates for chromosomes X, Y, and 13 in sperm nuclei sampled from seven XY/XX boars. 2n = 38,XX cells were identified in different nonhematopoietic tissues including testis (frequency, <8%). Similar aneuploidy rates were observed in the sperm nuclei of XY/XX and normal individuals (controls). Altogether, these results suggest that the presence of XX cells had no or only a very limited effect on the reproduction abilities of the analyzed boars.

  13. Angular dependence correction of MatriXX and its application to composite dose verification.

    PubMed

    Shimohigashi, Yoshinobu; Araki, Fujio; Tominaga, Hirofumi; Sakata, Junichi; Kawasaki, Keiichi; Kanetake, Nagisa; Iwashita, Yuki; Yoshimura, Saori; Kawakami, Tamami; Ishihara, Terunobu; Okuda, Tomoko; Kogo, Kasei

    2012-09-06

    We measured the angular dependence of central and off-axis detectors in a 2D ionization chamber array, MatriXX, and applied correction factors (CFs) to improve the accuracy of composite dose verification of IMRT and VMAT. The MatriXX doses were measured with a 10° step for gantry angles (θ) of 0°-180°, and a 1° step for lateral angles of 90°-110° in a phantom, with a 30 × 10 cm2 field for 6 MV and 10 MV photons. The MatriXX doses were also calculated under the same conditions by the Monte Carlo (MC) algorithm. The CFs for the angular dependence of MatriXX were obtained as a function of θ from the ratios of MatriXX-measured doses to MC-calculated doses, and normalized at θ = 0°. The corrected MatriXX were validated with different fields, various simple plans, and clinical treatment plans. The dose distributions were compared with those of MC calculations and film. The absolute doses were also compared with ionization chamber and MC-calculated doses. The angular dependence of MatriXX showed over-responses of up to 6% and 4% at θ = 90° and under-responses of up to 15% and 11% at 92°, and 8% and 5% at 180° for 6 MV and 10 MV photons, respectively. At 92°, the CFs for the off-axis detectors were larger by up to 7% and 6% than those for the central detectors for 6 MV and 10 MV photons, respectively, and were within 2.5% at other gantry angles. For simple plans, MatriXX doses with angular correction were within 2% of those measured with the ionization chamber at the central axis and off-axis. For clinical treatment plans, MatriXX with angular correction agreed well with dose distributions calculated by the treatment planning system (TPS) for gamma evaluation at 3% and 3 mm. The angular dependence corrections of MatriXX were useful in improving the measurement accuracy of composite dose verification of IMRT and VMAT.

  14. Evaluation of MatriXX for IMRT and VMAT dose verifications in peripheral dose regions

    SciTech Connect

    Han Zhaohui; Ng, Sook Kien; Bhagwat, Mandar S.; Lyatskaya, Yulia; Zygmanski, Piotr

    2010-07-15

    Purpose: MatriXX is a two-dimensional ion chamber array designed for IMRT/VMAT (RapidArc, IMAT, etc.) dose verifications. Its dosimetric properties have been characterized for megavoltage beams in a number of studies; however, to the best of the authors' knowledge, there is still a lack of an investigation into its performance in the peripheral or low dose regions. In this work, the authors have carried out a systematic study on this issue. Methods: The authors compare the performance of MatriXX with a cylindrical ion chamber in solid water phantoms in the peripheral dose regions. The comparisons are performed for a number of typical irradiation conditions that involve different gantry and/or MLC motions, field sizes, and distances to the target including static gantry/open fields, static gantry/sweeping MLC gap (mimicking an IMRT delivery), dynamic gantry/oscillating sweeping MLC gap (mimicking a VMAT delivery), as well as clinical IMRT and VMAT plans. Results: MatriXX, when used according to the manufacturer's recommendations, is found to disagree with an ion chamber in peripheral dose regions. This disagreement has been attributed to four types of MatriXX errors, namely, positive bias, over-response to scattered doses, round-off error, and angular dependence, all of which contribute to dose inaccuracies in the peripheral regions. The positive bias, which is independent of the dose level, is cumulative when MatriXX operates in the movie mode. The accumulation is proportional to the number of movie frames (snaps) when the sampling time is greater than 500 ms and is proportional to the overall movie time for a sampling time shorter than 500 ms. This behavior suggests multiple sources of the bias. MatriXX is also found to over-respond to peripheral doses by about 2.0% for the regions investigated in this work (3-15 cm from the field edge), where phantom scatter and collimator scatter dominate. Round-off error is determined to be due to insufficient precision in

  15. Das Schwimmen der Talitridae (Crustacea, Amphipoda): Funktionsmorphologie, Phänomenologie und Energetik

    NASA Astrophysics Data System (ADS)

    Vogel, Friedhelm

    1985-09-01

    The Talitridae, well-known for their jumping behaviour, swim with help of the tail-flip. This movement of the abdomen is also known from other amphipods like the Gammaridae which are normally not able to move by jerks outside the water. The suspected homology between the tail-flip when swimming and the jerky movement of the abdomen when jumping gave rise to this investigation, mainly based on high frequency film recordings, on the swimming of Hyale nilssonii, Orchestia cavimana, and Talitrus saltator (family Talitridae) as well as three related species of the families Gammaridae and Corophiidae. Comparative morphometrical and SEM-studies on the habitus of the species and the build of the involved limbs reveal the rather uniform construction of the Gammaridea; functional adaptation to the environment and to the way of living become apparent in minor alterations. The joints of the pleopods and uropods show a clear structural adaptation to the mechanical strain during swimming. The pleopods are moved metachronally in all examined species; angular velocity and rate of beating indicate the efficiency of the swimming movement. In the Talitridae, the metachronal beat of the pleopods is nearly always coupled with the tail-flip while in the Gammaridae and Corophiidae the tail-flip, in addition to the beat of the pleopods, is mostly used for a start from the subsoil or for a change in swimming direction. H. nilssonii, Gammarus locusta, and Corophium volutator, all inhabitants of the tidal zone in the North Sea shallows, turned out to be the “best” swimmers while the (semi-) terrestrially living species, O. cavimana and T. saltator, proved to be rather “poor” swimmers. This clearly indicates the ecological significance of swimming for the different species. Furthermore, the tailflip is found to be of rather subordinate importance. It contributes to a higher velocity if used moderately but is rather obstructive if a large angle is covered while extending and flexing the abdomen. The efficiency of swimming is inversely proportional to the efficiency of jumping in the three talitridean species. Thus, better adaptation to terrestrial life is accompanied by loss of swimming efficiency. Examined under the aspect of locomotional homology, it is concluded that the tail-flip used while swimming is homologous to the jerky movement of the abdomen used for jumping. The comparison of the swimming performance of the examined species with other crustaceans and some fishes illustrates the over-all good results of the Gammaridea.

  16. XY females do better than the XX in the African pygmy mouse, Mus minutoides.

    PubMed

    Saunders, Paul A; Perez, Julie; Rahmoun, Massilva; Ronce, Ophélie; Crochet, Pierre-André; Veyrunes, Frédéric

    2014-07-01

    All therian mammals have a similar XY/XX sex-determination system except for a dozen species. The African pygmy mouse, Mus minutoides, harbors an unconventional system in which all males are XY, and there are three types of females: the usual XX but also XX* and X*Y ones (the asterisk designates a sex-reversal mutation on the X chromosome). The long-term evolution of such a system is a paradox, because X*Y females are expected to face high reproductive costs (e.g., meiotic disruption and loss of unviable YY embryos), which should prevent invasion and maintenance of a sex-reversal mutation. Hence, mechanisms for compensating for the costs could have evolved in M. minutoides. Data gathered from our laboratory colony revealed that X*Y females do compensate and even show enhanced reproductive performance in comparison to the XX and XX*; they produce significantly more offspring due to (i) a higher probability of breeding, (ii) an earlier first litter, and (iii) a larger litter size, linked to (iv) a greater ovulation rate. These findings confirm that rare conditions are needed for an atypical sex-determination mechanism to evolve in mammals, and provide valuable insight into understanding modifications of systems with highly heteromorphic sex chromosomes. © 2014 The Author(s). Evolution © 2014 The Society for the Study of Evolution.

  17. A 46, XX SRY - negative man with infertility, and co-existing with chronic autoimmune thyroiditis.

    PubMed

    Mustafa, Ozbek; Mehmet, Erdogan

    2010-06-01

    46, XX male (de la Chapelle syndrome) is a rare syndrome with a frequency of 1 in 20,000-25,000 males. 46, XX males exist in different clinical categories with ambiguous genitalia or partially to fully mature male genitalia, in combination with complete or incomplete masculinisation. We herein report a case of SRY-negative XX male with complete masculinisation but with infertility, and co-existing with autoimmune thyroiditis. The patient had fully mature male genitalia with descended but small testes and no signs of undervirilisation. Peripheral blood culture for chromosome studies revealed 46 chromosomes with XX constitution. Repeat polymerase chain reaction analysis, using Y-specific sequence tagged sites analysing about 40 metaphases of genomic DNA, confirmed the absence of the Y chromosome, including any detectable SRY gene. We herein report a case of a man 46, XX male SRY with normal male phenotype and infertility. This case is the first reported case, co-existing with chronic autoimmune thyroiditis.

  18. The Caenorhabditis Elegans Gene Sdc-2 Controls Sex Determination and Dosage Compensation in Xx Animals

    PubMed Central

    Nusbaum, C.; Meyer, B. J.

    1989-01-01

    We have identified a new X-linked gene, sdc-2, that controls the hermaphrodite (XX) modes of both sex determination and X chromosome dosage compensation in Caenorhabditis elegans. Mutations in sdc-2 cause phenotypes that appear to result from a shift of both the sex determination and dosage compensation processes in XX animals to the XO modes of expression. Twenty-eight independent sdc-2 mutations have no apparent effect in XO animals, but cause two distinct phenotypes in XX animals: masculinization, reflecting a defect in sex determination, and lethality or dumpiness, reflecting a disruption in dosage compensation. The dosage compensation defect can be demonstrated directly by showing that sdc-2 mutations cause elevated levels of several X-linked transcripts in XX but not XO animals. While the masculinization is blocked by mutations in sex determining genes required for male development (her-1 and fem-3), the lethality, dumpiness and overexpression of X-linked genes are not, indicating that the effect of sdc-2 mutations on sex determination and dosage compensation are ultimately implemented by two independent pathways. We propose a model in which sdc-2 is involved in the coordinate control of both sex determination and dosage compensation in XX animals and acts in the regulatory hierarchy at a step prior to the divergence of the two pathways. PMID:2759421

  19. Serbian Astronomers in Science Citation Index in the XX Century

    NASA Astrophysics Data System (ADS)

    Dimitrijevic, Milan S.

    "Alpha". In 1996 Zrenjanin too got an organization of amateur astronomers, Astronomical Society "Milutin Milankovic". Moreover, in the book is given a selected bibliography of references concerning the history of astronomy among Serbs in XX century.

  20. A rare case of 46,XX gonadal dysgenesis and Mayer-Rokitansky-Kuster-Hauser syndrome.

    PubMed

    Manne, Sriharibabu; Veeraabhinav, C H; Jetti, Mounica; Himabindu, Yalamanchali; Donthu, Kiranmai; Badireddy, Mutyalarayudu

    2016-01-01

    46,XX gonadal dysgenesis is a rare genetically heterogeneous disorder characterized by underdeveloped ovaries with consequent, impuberism, primary amenorrhea, and hypergonadotropic hypogonadism. Mullerian agenesis or Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is characterized by congenital aplasia of the uterus and the upper part (2/3) of the vagina in a woman with normal development of secondary sexual characteristics and a normal 46,XX karyotype. The phenotypic manifestations of MRKH syndrome may sometimes overlap with various other syndromes and require accurate delineation. The coexistence of both these disorders is extremely rare. Here, we report a case of 46,XX gonadal dysgenesis and MRKH syndrome with anatomically dispersed congenital anomalies unique among reported cases.

  1. A rare case of 46,XX gonadal dysgenesis and Mayer-Rokitansky-Kuster-Hauser syndrome

    PubMed Central

    Manne, Sriharibabu; Veeraabhinav, C. H.; Jetti, Mounica; Himabindu, Yalamanchali; Donthu, Kiranmai; Badireddy, Mutyalarayudu

    2016-01-01

    46,XX gonadal dysgenesis is a rare genetically heterogeneous disorder characterized by underdeveloped ovaries with consequent, impuberism, primary amenorrhea, and hypergonadotropic hypogonadism. Mullerian agenesis or Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is characterized by congenital aplasia of the uterus and the upper part (2/3) of the vagina in a woman with normal development of secondary sexual characteristics and a normal 46,XX karyotype. The phenotypic manifestations of MRKH syndrome may sometimes overlap with various other syndromes and require accurate delineation. The coexistence of both these disorders is extremely rare. Here, we report a case of 46,XX gonadal dysgenesis and MRKH syndrome with anatomically dispersed congenital anomalies unique among reported cases. PMID:28216916

  2. High temperature increases the masculinization rate of the all-female (XX) rainbow trout "Mal" population.

    PubMed

    Valdivia, Karina; Jouanno, Elodie; Volff, Jean-Nicolas; Galiana-Arnoux, Delphine; Guyomard, René; Helary, Louise; Mourot, Brigitte; Fostier, Alexis; Quillet, Edwige; Guiguen, Yann

    2014-01-01

    Salmonids are generally considered to have a robust genetic sex determination system with a simple male heterogamety (XX/XY). However, spontaneous masculinization of XX females has been found in a rainbow trout population of gynogenetic doubled haploid individuals. The analysis of this masculinization phenotype transmission supported the hypothesis of the involvement of a recessive mutation (termed mal). As temperature effect on sex differentiation has been reported in some salmonid species, in this study we investigated in detail the potential implication of temperature on masculinization in this XX mal-carrying population. Seven families issued from XX mal-carrying parents were exposed from the time of hatching to different rearing water temperatures ((8, 12 and 18°C), and the resulting sex-ratios were confirmed by histological analysis of both gonads. Our results demonstrate that masculinization rates are strongly increased (up to nearly two fold) at the highest temperature treatment (18°C). Interestingly, we also found clear differences between temperatures on the masculinization of the left versus the right gonads with the right gonad consistently more often masculinized than the left one at lower temperatures (8 and 12°C). However, the masculinization rate is also strongly dependent on the genetic background of the XX mal-carrying families. Thus, masculinization in XX mal-carrying rainbow trout is potentially triggered by an interaction between the temperature treatment and a complex genetic background potentially involving some part of the genetic sex differentiation regulatory cascade along with some minor sex-influencing loci. These results indicate that despite its rather strict genetic sex determinism system, rainbow trout sex differentiation can be modulated by temperature, as described in many other fish species.

  3. Long term outcomes in 46, XX adult patients with congenital adrenal hyperplasia reared as males.

    PubMed

    Khattab, A; Yau, M; Qamar, A; Gangishetti, P; Barhen, A; Al-Malki, S; Mistry, H; Anthony, W; Toralles, M B; New, Maria I

    2017-01-01

    Patients with Congenital Adrenal Hyperplasia (CAH) owing to 21-hydroxylase deficiency and whose karyotype is 46, XX are usually assigned to the female gender. Reported herein are the long term outcomes in three patients with CAH whose karyotype is 46, XX and who were reared as males. A retrospective review of three CAH patients with a 46, XX karyotype who were reared as males was conducted. Gender assignment, clinical and biochemical data, pre and post-genitoplasty genital examinations were reviewed. Gender identity was tested by an extensive questionnaire. Gender role, sexual preference, marital status and sexual satisfaction were evaluated by interview. The three patients were genotyped for the CYP21A2 gene confirming the diagnosis of CAH. Owing to genital virilization, cultural preferences for male gender and the lack of newborn screening programs the three patients reported herein were assigned to the male gender at birth before the diagnosis of CAH was established. In adulthood the patients remained significantly virilized. Thorough psychosexual assessments in adulthood revealed well established male gender identities compatible with their male gender assignments at birth. In all three patients, gender role and behavior were consistent with male gender identity including sexual intercourse with female partners. The three patients reported herein revealed that male gender assignment to CAH patients with a 46, XX karyotype may have a successful outcome providing there is strong parental support and expert endocrine care. No standard guidelines have been published for the gender assignment of CAH patients with a 46, XX karyotype and genital ambiguity. More studies concerning gender assignment in CAH patients with a 46, XX karyotype reared as males are needed.

  4. 49 CFR 1242.48 - Work and other non-revenue equipment (account XX-27-47).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Work and other non-revenue equipment (account XX-27-47). 1242.48 Section 1242.48 Transportation Other Regulations Relating to Transportation... RAILROADS 1 Operating Expenses-Equipment § 1242.48 Work and other non-revenue equipment (account XX-27-47...

  5. Excited state properties of naphtho-homologated xxDNA bases and effect of methanol solution, deoxyribose, and base pairing.

    PubMed

    Zhang, Laibin; Ren, Tingqi; Tian, Jianxiang; Yang, Xiuqin; Zhou, Liuzhu; Li, Xiaoming

    2013-04-18

    Design and synthesis of fluorescent nucleobase analogues for studying structures and dynamics of nucleic acids have attracted much attention in recent years. In the present work, a comprehensive theoretical study of electronic transitions of naphtho-homologated base analogues, namely, xxC, xxT, xxA, and xxG, was performed. The nature of the low-lying excited states was discussed, and the results were compared with those of x-bases. Geometrical characteristics of the lowest excited singlet ππ* states were explored using the CIS method. The calculated excitation maxima are 423, 397, 383, and 357 nm for xxA, xxG, xxC, and xxT, respectively, and they are greatly red-shifted compared with x-bases and natural bases, allowing them to be selectively excited in the presence of the natural bases. In the gas phase, the fluorescence from them would be expected to occur around 497, 461, 457, and 417 nm, respectively. The effects of methanol solution, deoxyribose, and base paring with their complementary natural bases on the relevant absorption and emission spectra of these modified bases were also examined.

  6. 78 FR 29131 - Solar Star California XX, LLC; Supplemental Notice that Initial Market-Based Rate Filing Includes...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-17

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Solar Star California XX, LLC; Supplemental Notice that Initial Market-Based... above-referenced proceeding, of Solar Star California XX, LLC's application for market-based...

  7. 49 CFR 1242.55 - Administration (account XX-51-01).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Administration (account XX-51-01). 1242.55 Section 1242.55 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) ACCOUNTS, RECORDS AND REPORTS SEPARATION OF...

  8. 49 CFR 1242.57 - Dispatching trains (account XX-51-58).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Dispatching trains (account XX-51-58). 1242.57 Section 1242.57 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) ACCOUNTS, RECORDS AND REPORTS SEPARATION OF...

  9. 49 CFR 1242.59 - Train inspection and lubrication (account XX-51-62).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Train inspection and lubrication (account XX-51-62). 1242.59 Section 1242.59 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) ACCOUNTS, RECORDS AND REPORTS SEPARATION OF...

  10. Diploid/Tetraploid Mosaicism in the Offspring of a 46XX/47XXX Mosaic Mother

    PubMed Central

    Reddy, Churku Mohan; Singh, D. N.; Crump, E. Perry

    1977-01-01

    A 10½-year-old boy with an IQ of 71, short stature, and isolated growth hormone deficiency was found to have diploid/tetraploid mosaicism. He was born to a 46xx/47xxx mosaic mother. The mother was found to be moderately mentally retarded but showed no other abnormalities. A review of literature pertinent to this case is presented. PMID:904007

  11. Studying the thermally entangled state of a three-qubit Heisenberg XX ring via quantum teleportation

    SciTech Connect

    Yeo, Ye

    2003-08-01

    We consider quantum teleportation as a tool to investigate the thermally entangled state of a three-qubit Heisenberg XX ring. Our investigation reveals interesting aspects of quantum entanglement not reflected by the pairwise thermal concurrence of the state. In particular, two mixtures of different pairs of W states, which result in the same concurrence, could yield very different average teleportation fidelities.

  12. 46 XX karyotype during male fertility evaluation; case series and literature review.

    PubMed

    Majzoub, Ahmad; Arafa, Mohamed; Starks, Christopher; Elbardisi, Haitham; Al Said, Sami; Sabanegh, Edmund

    2017-01-01

    Forty-six XX disorder of sex development is an uncommon medical condition observed at times during the evaluation of a man's fertility. The following is a case series and literature review of phenotypically normal men diagnosed with this karyotype. Our goal is to comprehend the patients' clinical presentation as well as their laboratory results aiming to explore options available for their management. A formal literature review through PubMed and MEDLINE databases was performed using "46 XX man" as a word search. A total of 55 patients, including those conveyed in this article were diagnosed with a 46 XX karyotype during their fertility evaluation. The patients' mean age ± s.d. was 34 ± 10 years and their mean height ± s.d. was 166 ± 6.5 cm. Overall, they presented with hypergonadotropic hypogonadism. Sexual dysfunction, reduced hair distribution, and gynecomastia were reported in 20% (4/20), 25.8% (8/31), and 42% (13/31) of the patients, respectively. The SRY gene was detected in 36 (83.7%) and was absent in the remaining seven (16.3%) patients. We found that a multidisciplinary approach to management is preferred in 46 XX patients. Screening for remnants of the mullerian ducts and for malignant transformation in dysgenetic gonads is imperative. Hypogonadism should be addressed, while fertility options are in vitro fertilization with donor sperm or adoption.

  13. 45,X/46,XX karyotype mitigates the aberrant craniofacial morphology in Turner syndrome.

    PubMed

    Rizell, Sara; Barrenäs, Marie-Louise; Andlin-Sobocki, Anna; Stecksén-Blicks, Christina; Kjellberg, Heidrun

    2013-08-01

    The aim of this project was to study the impact on craniofacial morphology from Turner syndrome (TS) karyotype, number of intact X chromosomal p-arms, and age as well as to compare craniofacial morphology in TS with healthy females. Lateral radiographs from 108 females with TS, ranging from 5.4 to 61.6 years, were analysed. The TS females were divided into four karyotype groups: 1. monosomy (45,X), 2. mosaic (45,X/46,XX), 3. isochromosome, and 4. other, as well as according to the number of intact X chromosomal p-arms. The karyotype was found to have an impact on craniofacial growth, where the mosaic group, with presence of 46,XX cell lines, seems to exhibit less mandibular retrognathism as well as fewer statistically significant differences compared to the reference group than the 45,X karyotype. Isochromosomes had more significant differences versus the reference group than 45,X/46,XX but fewer than 45,X. To our knowledge, this is the first time the 45,X/46,XX and isochromosome karyotypes are divided into separate groups studying craniofacial morphology. Impact from p-arm was found on both maxillary and mandibular length. Compared to healthy females, TS expressed a shorter posterior and flattened cranial base, retrognathic, short and posteriorly rotated maxilla and mandible, increased height of ramus, and relatively shorter posterior facial height. The impact of age was found mainly on mandibular morphology since mandibular retrognathism and length were more discrepant in older TS females than younger.

  14. 76 FR 57006 - Proposed Generic Communications; Draft NRC Regulatory Issue Summary 2011-XX; NRC Regulation of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ...-XX; NRC Regulation of Military Operational Radium-226; Reopening of Comment Period AGENCY: Nuclear... military operational Radium-226 for a 60-day public comment period that ended on September 6, 2011. The NRC... amended its regulations to include jurisdiction over discrete sources of radium-226,...

  15. True hermaphroditism in a horned goat with 60XX/60XY chimerism.

    PubMed Central

    Batista, M; González, F; Cabrera, F; Palomino, E; Castellano, E; Calero, P; Gracia, A

    2000-01-01

    Anatomical, behavioral, histological, endocrinological, and cytogenetic characteristics were determined in a horned intersex goat. Histology of the gonads confirmed that the goat was a true hermaphrodite. Cytogenetic analysis showed that it was a chimera (60XX/60XY). Use of laparoscopy allowed determination of characteristics of the internal gonads. Images Figure 1. Figure 2. PMID:10907580

  16. 40 CFR Table 1 to Subpart Xx of... - Hazardous Air Pollutants

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 11 2013-07-01 2013-07-01 false Hazardous Air Pollutants 1 Table 1 to Subpart XX of Part 63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES...

  17. 40 CFR Table 1 to Subpart Xx of... - Hazardous Air Pollutants

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 11 2012-07-01 2012-07-01 false Hazardous Air Pollutants 1 Table 1 to Subpart XX of Part 63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES...

  18. 40 CFR Table 1 to Subpart Xx of... - Hazardous Air Pollutants

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 10 2011-07-01 2011-07-01 false Hazardous Air Pollutants 1 Table 1 to Subpart XX of Part 63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED...

  19. 40 CFR Table 1 to Subpart Xx of... - Hazardous Air Pollutants

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 10 2010-07-01 2010-07-01 false Hazardous Air Pollutants 1 Table 1 to Subpart XX of Part 63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED...

  20. 46 XX karyotype during male fertility evaluation; case series and literature review

    PubMed Central

    Majzoub, Ahmad; Arafa, Mohamed; Starks, Christopher; Elbardisi, Haitham; Al Said, Sami; Sabanegh, Edmund

    2017-01-01

    Forty-six XX disorder of sex development is an uncommon medical condition observed at times during the evaluation of a man's fertility. The following is a case series and literature review of phenotypically normal men diagnosed with this karyotype. Our goal is to comprehend the patients’ clinical presentation as well as their laboratory results aiming to explore options available for their management. A formal literature review through PubMed and MEDLINE databases was performed using “46 XX man” as a word search. A total of 55 patients, including those conveyed in this article were diagnosed with a 46 XX karyotype during their fertility evaluation. The patients’ mean age ± s.d. was 34 ± 10 years and their mean height ± s.d. was 166 ± 6.5 cm. Overall, they presented with hypergonadotropic hypogonadism. Sexual dysfunction, reduced hair distribution, and gynecomastia were reported in 20% (4/20), 25.8% (8/31), and 42% (13/31) of the patients, respectively. The SRY gene was detected in 36 (83.7%) and was absent in the remaining seven (16.3%) patients. We found that a multidisciplinary approach to management is preferred in 46 XX patients. Screening for remnants of the mullerian ducts and for malignant transformation in dysgenetic gonads is imperative. Hypogonadism should be addressed, while fertility options are in vitro fertilization with donor sperm or adoption. PMID:27297128

  1. [Diseases and causes of death of outstanding creative and scientific figures of XVII-XX centuries].

    PubMed

    Martsinkovs'kyĭ, I B

    2007-01-01

    The article reviewed the literature which analyzes clinical symptoms and causes of some creative and scientific figures of XVII-XX centuries. A conclusion has been made that there are not enough works with professional retrospective investigation of somatic diseases and causes of death of ukrainain outstanding cultural and scientific people in today's national medical literature.

  2. A mutation in the nucleoporin-107 gene causes XX gonadal dysgenesis

    PubMed Central

    Weinberg-Shukron, Ariella; Renbaum, Paul; Kalifa, Rachel; Zeligson, Sharon; Ben-Neriah, Ziva; Dreifuss, Amatzia; Abu-Rayyan, Amal; Maatuk, Noa; Fardian, Nilly; Rekler, Dina; Kanaan, Moien; Samson, Abraham O.; Levy-Lahad, Ephrat; Gerlitz, Offer; Zangen, David

    2015-01-01

    Ovarian development and maintenance are poorly understood; however, diseases that affect these processes can offer insights into the underlying mechanisms. XX female gonadal dysgenesis (XX-GD) is a rare, genetically heterogeneous disorder that is characterized by underdeveloped, dysfunctional ovaries, with subsequent lack of spontaneous pubertal development, primary amenorrhea, uterine hypoplasia, and hypergonadotropic hypogonadism. Here, we report an extended consanguineous family of Palestinian origin, in which 4 females exhibited XX-GD. Using homozygosity mapping and whole-exome sequencing, we identified a recessive missense mutation in nucleoporin-107 (NUP107, c.1339G>A, p.D447N). This mutation segregated with the XX-GD phenotype and was not present in available databases or in 150 healthy ethnically matched controls. NUP107 is a component of the nuclear pore complex, and the NUP107-associated protein SEH1 is required for oogenesis in Drosophila. In Drosophila, Nup107 knockdown in somatic gonadal cells resulted in female sterility, whereas males were fully fertile. Transgenic rescue of Drosophila females bearing the Nup107D364N mutation, which corresponds to the human NUP107 (p.D447N), resulted in almost complete sterility, with a marked reduction in progeny, morphologically aberrant eggshells, and disintegrating egg chambers, indicating defective oogenesis. These results indicate a pivotal role for NUP107 in ovarian development and suggest that nucleoporin defects may play a role in milder and more common conditions such as premature ovarian failure. PMID:26485283

  3. Prenatal diagnosis of 45,X/46,XX mosaicism and 45,X: implications for postnatal outcome.

    PubMed Central

    Koeberl, D D; McGillivray, B; Sybert, V P

    1995-01-01

    The prognosis for 45,X/46,XX mosaicism diagnosed prenatally has yet to be established. We report our experience with 12 patients in whom prenatal diagnosis of 45,X/46,XX mosaicism was detected by amniocentesis for advanced maternal age or decreased maternal serum alpha-feto protein and compared them with 41 45,X/46,XX patients diagnosed postnatally. The girls in the prenatal group range in age from 3 mo to 10 years. All have had normal linear growth. Four had structural anomalies including: ASD (n = 1); ptosis and esotropia (n = 1); labial fusion (n = 1); and urogenital sinus, dysplastic kidneys, and hydrometrocolpos (n = 1). Gonadotropins were measured in seven; one had elevated luteinizing hormone/FSH at 3 mo of age. One has developmental delay and seizures as well as ophthalmologic abnormalities. None would have warranted karyotyping for clinical suspicion of Turner syndrome. The prevalence of 45,X/46,XX mosaicism is 10-fold higher among amniocenteses than in series of postnatally diagnosed individuals with Turner syndrome, which suggests that most individuals with this karyotype escape detection and that an ascertainment bias exists toward those with clinically evident abnormalities. The phenomenon of a milder phenotype for the prenatal group is similar to that observed for 45,X/46,XY diagnosed prenatally. Prenatal counseling for 45,X/46,XX in the absence of such ultrasound abnormalities as hydrops fetalis should take into account the expectation of a milder phenotype (except, possibly, with respect to developmental delay) than that of patients ascertained postnatally. The same does not hold true for 45,x diagnosed prenatally. PMID:7668295

  4. Clinical review of 95 patients with 46,XX disorders of sex development based on the new Chicago classification.

    PubMed

    Öcal, Gönül; Berberoğlu, Merih; Sıklar, Zeynep; Aycan, Zehra; Hacıhamdioglu, Bülent; Erdeve, Şenay S; Çamtosun, Emine; Kocaay, Pınar; Ruhi, Hatice I; Kılıç, Birim G; Tukun, Ajlan

    2015-02-01

    The aim of our study was to determine the etiologic distribution of 46,XX disorder of sexual development (DSD) according to the new DSD classification system and to evaluate the clinical features of this DSD subgroup in our patient cohort. The evaluation criteria and clinical findings of 95 46,XX patients were described by clinical presentation, gonadal morphology, genital anatomy, associated dysmorphic features, presence during prenatal period with/without postnatal virilization, hormonal characteristics, and presence or absence of steroidogenic defects among 319 patients with DSD. Types and ratios of each presentation of our 95 patients with 46,XX DSD were as follows: 82 had androgen excess (86.3%): (74 had classical congenital adrenal hyperplasia, 2 had CAH variant possibility of P450-oxidoreductase gene defect), 6 had disorders of ovarian development (6.3%): (1 patient had gonadal dysgenesis with virilization at birth with bilateral streak gonad, 4 patients had complete gonadal dysgenesis, and 1 patient had ovotesticular DSD) and 7 had other 46,XX DSD. Two sisters, who had 46,XX complete gonadal dysgenesis,were diagnosed with Perrault Syndrome with ovarian failure due to streak gonads and associated with sensorineural deafness. 46,XX DSD are usually derived from intrauterine virilization and CAH is the most common cause of 46,XX DSD due to fetal androgen exposure. Copyright © 2015 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

  5. Subtractive and differential hybridization molecular analyses of Ceratitis capitata XX/XY versus XX embryos to search for male-specific early transcribed genes

    PubMed Central

    2014-01-01

    The agricultural pest Ceratitis capitata, also known as the Mediterranean fruit fly or Medfly, is a fruit crop pest of very high economic relevance in different continents. The strategy to separate Ceratitis males from females (sexing) in mass rearing facilities is a useful step before the sterilization and release of male-only flies in Sterile Insect Technique control programs (SIT). The identification of genes having early embryonic male-specific expression, including Y-linked genes, such as the Maleness factor, could help to design novel and improved methods of sexing in combination with transgenesis, aiming to confer conditional female-specific lethality or female-to-male sexual reversal. We used a combination of Suppression Subtractive Hybrydization (SSH), Mirror Orientation Selection (MOS) and differential screening hybridization (DSH) techniques to approach the problem of isolating corresponding mRNAs expressed in XX/XY embryos versus XX-only embryos during a narrow developmental window (8-10 hours after egg laying, AEL ). Here we describe a novel strategy we have conceived to obtain relatively large amounts of XX-only embryos staged at 8-10 h AEL and so to extract few micrograms of polyA+ required to apply the complex technical procedure. The combination of these 3 techniques led to the identification of a Y-linked putative gene, CcGm2, sharing high sequence identity to a paralogous gene, CcGm1, localized either on an autosome or on the X chromosome. We propose that CcGm2 is a first interesting putative Y-linked gene which could play a role in sex determination. The function exterted by this gene should be investigated by novel genetic tools, such as CRISPR-CAS9, which will permit to target only the Y-linked paralogue, avoiding to interfere with the autosomal or X-linked paralogue function. PMID:25472628

  6. Subtractive and differential hybridization molecular analyses of Ceratitis capitata XX/XY versus XX embryos to search for male-specific early transcribed genes.

    PubMed

    Salvemini, Marco; D'Amato, Rocco; Petrella, Valeria; Ippolito, Domenica; Ventre, Giuseppe; Zhang, Ying; Saccone, Giuseppe

    2014-01-01

    The agricultural pest Ceratitis capitata, also known as the Mediterranean fruit fly or Medfly, is a fruit crop pest of very high economic relevance in different continents. The strategy to separate Ceratitis males from females (sexing) in mass rearing facilities is a useful step before the sterilization and release of male-only flies in Sterile Insect Technique control programs (SIT). The identification of genes having early embryonic male-specific expression, including Y-linked genes, such as the Maleness factor, could help to design novel and improved methods of sexing in combination with transgenesis, aiming to confer conditional female-specific lethality or female-to-male sexual reversal. We used a combination of Suppression Subtractive Hybrydization (SSH), Mirror Orientation Selection (MOS) anddifferential screening hybridization (DSH) techniques to approach the problem of isolating corresponding mRNAs expressed in XX/XY embryos versus XX-only embryos during a narrow developmental window (8-10 hours after egg laying, AEL ). Here we describe a novel strategy we have conceived to obtain relatively large amounts of XX-only embryos staged at 8-10 h AEL and so to extract few micrograms of polyA+ required to apply the complex technical procedure. The combination of these 3 techniques led to the identification of a Y-linked putative gene, CcGm2, sharing high sequence identity to a paralogous gene, CcGm1, localized either on an autosome or on the X chromosome. We propose that CcGm2 is a first interesting putative Y-linked gene which could play a role in sex determination. The function exterted by this gene should be investigated by novel genetic tools, such as CRISPR-CAS9, which will permit to target only the Y-linked paralogue, avoiding to interfere with the autosomal or X-linked paralogue function.

  7. Case of 46,XX/47,XY, +21 chimerism in a newborn infant with ambiguous genitalia

    SciTech Connect

    Sawai, Tomoko; Yoshimoto, Masaaki; Kinoshita, Ei-ichi; Baba, Tsuneyoshi; Matsumoto, Tadashi; Tsuji, Yoshiro, Niikawa, Norio; Fukuda, Shinpei; Harada, Naoki

    1994-02-15

    The authors describe the whole-body chimerism in a newborn infant with small phallus, pseudo-vaginal perineal hypospadias, and a bifid scrotum containing gonads. The human testis determining factor gene (SRY) was detected by PCR amplification. GTG-banding chromosome analysis in peripheral blood lymphocytes and cultured fibroblasts derived from right cubital skin showed a 46,XX/47,XY, +21 karyotype. Their ratios in each cell line were 294:5 and 178:7, respectively. QFQ-banding chromosome analysis documented 3 heteromorphic satellites on trisomic chromsomes 21 in the 47,XY,+21 cell line and a homozygous satellite pattern in the 46,XX cell line. Heteromorphic patterns of chromsomes 4, 13, 14, and 22 were also different between the two cell lines. To our knowledge, such disomy/trisomy chimeras have not been described previously. 10 refs., 3 figs.

  8. Case of 46,XX/47,XY, +21 chimerism in a newborn infant with ambiguous genitalia.

    PubMed

    Sawai, T; Yoshimoto, M; Kinoshita, E; Baba, T; Matsumoto, T; Tsuji, Y; Fukuda, S; Harada, N; Niikawa, N

    1994-02-15

    We describe whole-body chimerism in a newborn infant with small phallus, pseudo-vaginal perineal hypospadias, and a bifid scrotum containing gonads. The human testis determining factor gene (SRY) was detected by PCR amplification. GTG-banding chromosome analysis in peripheral blood lymphocytes and cultured fibroblasts derived from right cubital skin showed a 46,XX/47,XY, +21 karyotype. Their ratios in each cell line were 294:5 and 178:7, respectively. QFQ-banding chromosome analysis documented 3 heteromorphic satellites on trisomic chromosomes 21 in the 47,XY, +21 cell line and a homozygous satellite pattern in the 46,XX cell line. Heteromorphic patterns of chromosomes 4, 13, 14, and 22 were also different between the two cell lines. To our knowledge, such disomy/trisomy chimeras have not been described previously.

  9. Genetic and physical analyses of Methylobacterium organophilum XX genes encoding methanol oxidation

    SciTech Connect

    Machlin, S.M.; Tam, P.E.; Bastien, C.A.; Hanson, R.S.

    1988-01-01

    When allyl alcohol was used as a suicide substrate, spontaneous mutants and UV light- and nitrous acid-generated mutants of Methylobacterium organophilum XX were selected which grew on methylamine but not on methanol. There was no detectable methanol dehydrogenase (MDH) activity in crude extracts of these mutants, yet Western blots revealed that some mutants still produced MDH protein. Complementation of 50 mutants by a cosmid gene bank of M. organophilum XX demonstrated that three major regions of the genome, each of which was separated by a minimum of 40 kilobases, were required for expression of active MDH. By subcloning and Tn5 insertion mutagenesis of subcloned fragments, at least 11 genes clustered within these three regions were subsequently identified. The identity of the MDH structural gene, which was initially determined by hybridization to the structural gene of Methylobacterium sp. strain AM1, was confirmed by Western blot analysis of an MDH-..beta..-galactosidase fusion protein.

  10. A case of sex reversal syndrome with sex-determining region (XX male).

    PubMed

    Yamamoto, M; Yokoi, K; Katsuno, S; Hibi, H; Miyake, K

    1995-12-01

    We examined a 32-year-old man with a 4-year history of infertility. The man's sex life, male hair pattern, and penis were normal, and he had no history of erection problems. Left and right testicular volumes were 2 ml and 3 ml, respectively. Semen analysis showed no sperm. The endocrine panel revealed increased serum luteinizing hormone and follicle-stimulating hormone levels, and a normal serum testosterone level. A testicular biopsy demonstrated that both Leydig cell and Sertoli cell hyperplasia were present, and that no germ cells were found in the tubules. A chromosome analysis done on the peripheral blood lymphocytes revealed a karyotype of 46, XX. We identified the sex-determining region, Y, by polymerase chain reaction using Y-specific probes in this patient. The diagnosis was XX male.

  11. XX true hermaphroditism in southern African blacks: an enigma of primary sexual differentiation.

    PubMed Central

    Ramsay, M; Bernstein, R; Zwane, E; Page, D C; Jenkins, T

    1988-01-01

    A high incidence of 46,XX true hermaphroditism exists among southern African blacks. The gonadal distribution and clinical presentation of 38 patients are described. The aim of our study on 11 families with histologically proven XX true hermaphroditism was to determine whether a common genetic or environmental etiology could be identified. Pedigree analysis excluded the presence of a simple inheritance pattern, and no constant environmental factors could be implicated. Hybridization studies with Y chromosome--specific probes (pDP132, pDP61, pDP105, pDP31, pDP97, and pY431-HinfA) excluded the presence of a large portion of Yp in these patients. It is possible that smaller portions of the Y chromosome or one or more X-linked or autosomal mutations, either interacting and/or with incomplete penetrance, are present. Images Figure 2 PMID:3163890

  12. An XXX male resulting from paternal X-Y interchange and maternal X-X nondisjunction.

    PubMed Central

    Annerén, G; Andersson, M; Page, D C; Brown, L G; Berg, M; Läckgren, G; Gustavson, K H; de la Chapelle, A

    1987-01-01

    A 2-year-old boy was found to have a 47,XXX karyotype. Restriction-fragment-length-polymorphism analysis showed that, of his three X chromosomes, one is of paternal and two are of maternal origin. The results of Y-DNA hybridization were reminiscent of those in XX males in two respects. First, hybridization to Southern transfers revealed the presence in this XXX male of sequences derived from the Y-chromosomal short arm. Second, in situ hybridization showed that this Y DNA was located on the tip of the X-chromosomal short arm. We conclude that this XXX male resulted from the coincidence of X-X nondisjunction during maternal meiosis and aberrant X-Y interchange either during or prior to paternal meiosis. Images Fig. 1 Fig. 2 Fig. 3 Fig. 4 Fig. 5 PMID:2889356

  13. Absence of Y-specific DNA sequences in human 46,XX true hermaphrodites and in 45,X mixed gonadal dysgenesis.

    PubMed

    Waibel, F; Scherer, G; Fraccaro, M; Hustinx, T W; Weissenbach, J; Wieland, J; Mayerová, A; Back, E; Wolf, U

    1987-08-01

    A search for Y-specific DNA sequences has been performed in a sample of seven 46,XX true hermaphrodites and one 45,X mixed gonadal dysgenesis case and compared with a sample of 11 XX males. Using six Y-specific DNA probes no hybridization signal was obtained in the hermaphrodite group; in contrast, all XX males gave a positive signal with at least one probe. This difference is statistically highly significant. We conclude that the aetiology of true hermaphroditism is different from that of the XX male syndrome. As all cases of the hermaphrodite group are positive for the serological sex-specific antigen (Sxs) it is concluded that this antigen can be present even in the absence of Y-specific DNA.

  14. Teleportation via thermally entangled states of a two-qubit Heisenberg XX chain

    SciTech Connect

    Yeo Ye

    2002-12-01

    Recently, entanglement teleportation has been investigated by Lee and Kim [Phys. Rev. Lett. 84, 4236 (2000)]. In this paper we study entanglement teleportation via two separate thermally entangled states of a two-qubit Heisenberg XX chain. We established the condition under which the parameters of the model have to satisfy in order to teleport entanglement. The necessary minimum amount of thermal entanglement for some fixed strength of exchange coupling is a function of the magnetic field and the temperature.

  15. Discordant sex in monozygotic XXY/XX twins: a case report.

    PubMed

    Tachon, G; Lefort, G; Puechberty, J; Schneider, A; Jeandel, C; Boulot, P; Prodhomme, O; Meyer, P; Taviaux, S; Touitou, I; Pellestor, F; Geneviève, D; Gatinois, V

    2014-12-01

    We report a case of discordant phenotypic sex in monozygotic twins mosaic 47,XXY/46,XX: monozygotic heterokaryotypic twins. The twins presented with cognitive and comprehension delay, behavioural and language disorders, all symptoms frequently reported in Klinefelter syndrome. Molecular zygosity analysis with several markers confirmed that the twins are in effect monozygotic (MZ). Array comparative genomic hybridization found no evidence for the implication of copy number variation in the phenotypes. Ultrasound scans of the reproductive organs revealed no abnormalities. Endocrine tests showed a low testosterone level in Twin 1 (male phenotype) and a low gonadotrophin level in Twin 2 (female phenotype) which, combined with the results from ultrasound examination, provided useful information for potentially predicting the future fertility potential of the twins. Blood karyotypes revealed the presence of a normal 46,XX cell line and an aneuploïd 47,XXY cell line in both patients. Examination of the chromosome constitutions of various tissues such as blood, buccal smear and urinary sediment not surprisingly showed different proportions for the 46,XX and 47,XXY cell lines, which most likely explains the discordant phenotypic sex and mild Klinefelter features. The most plausible underlying biological mechanism is a post-zygotic loss of the Y chromosome in an initially 47,XXY zygote. This would result in an embryo with both 46,XX and 47,XXY cells lines which could subsequently divide into two monozygotic embryos through a twinning process. The two cell lines would then be distributed differently between tissues which could result in phenotypic discordances in the twins. These observations emphasize the importance of regular paediatric evaluations to determine the optimal timing for fertility preservation measures and to detect new Klinefelter features which could appear throughout childhood in the two subjects.

  16. Military Process Specification for Type 46XX Powder-Forged Weapon Components

    DTIC Science & Technology

    1985-08-20

    one with low carbon or carburizing steels (Figure 18). Fracture Toughness Only one paper contained fracture toughness data for P/F 10XX steels . The...201-213. 8. Brown, G. T., "The Core ’Properties of a Range of Powder-Forged Steels ’ for Carburizing Applications," Powder Metallurgy, vol. 20, no...621205H84001, Dover, NJ: ARRADC0M, October 1980. Smith, A. 0., "Hardenability of Forged Alloy Steel Powders for Carburizing Ap- plications," Inland

  17. [New aspects of diagnosing and treating pure gonadal dysgenesis 46XY and 46XX].

    PubMed

    Baron, J; Warenik-Szymankiewicz, A; Miedzianowski, J; Baron, J J

    1993-01-01

    Among 67 women with pure gonadal dysgenesis, karyotype 46XY was found in 46 and karyotype 46XX in 21 (26.3% of all intersexual subjects). Karyotype 46XY was either of pure type or mosaicism 45,X/46,XY (10.9%). Primary amenorrhea, underdevelopment of mammary glands and lack or poor development of pubic hair were the main complaints of the patients. In gonadal dysgenesis 46XY mammary glands were developed in 21.8% and pubic hair in 26% suggesting the presence within the gonads of the hormonally active tumor or the state after hormonal treatment. The patients with gonadal dysgenesis 46XX had lowered levels of estrogens and elevated levels of FSH and LH. Karyotype 46XY was not associated with evident changes in hormonal levels. Estrogens were both low and normal, and FSH was elevated (21.5 + 16.6 ug/ml) or normal (3.2-5.0 ng/ml). Total testosterone values were normal or slightly elevated. Such situation can be explained by the presence in some patients of tumors secreting either estrogens or androgens. Taeniform character of gonads was observed by ultrasonography whenever the presence of gonadal tumor was excluded. Histology of specimens taken from gonads or tumors demonstrated the presence of dysgerminoma or gonadoblastoma type of malignancy in 53.1%, foci or proliferation of the Leydig cells in 31.3% and typical morphology of residual gonads without germinal cells only in 12.5%. The differentiation between pure gonadal dysgenesis 46XX and primary ovarian insufficiency is required whenever no characteristic pattern emerges from clinical, hormonal, cytogenetic or ultrasonographic examination. Diagnosis of pure gonadal dysgenesis 46XX can be finally confirmed by the absence of gonocytes in the residual gonad. Besides of removal of gonads or tumors by surgery, the treatment of patients with 46XY karyotype consists in cyclic administration of estrogens and progestagens restoring menstruation and bringing development of secondary sex attributes.

  18. A real time integrated environment for Motorola 680xx-based VME and FASTBUS modules

    SciTech Connect

    Berg, D.; Heinicke, P.; MacKinnon, B.; Nicinski, T.; Oleynik, G.

    1989-05-01

    The Software Components Group pSOS operating system kernel and pROBE debugger have been extended to support the Fermilab PAN-DA system for a variety of Motorola 680xx-based VME and FASTBUS modules. These extensions include: a multi-tasking, reentrant implementation of Microtec C/Pascal; a serial port driver for terminal I/O and data transfer; a message reporting facility; and enhanced debugging tools. 5 refs., 1 fig.

  19. Karyotype 69,XXX/47,XX,+15 in a 2 1/2 year old child.

    PubMed Central

    Dean, J; Cohen, G; Kemp, J; Robson, L; Tembe, V; Hasselaar, J; Webster, B; Lammi, A; Smith, A

    1997-01-01

    We present the clinical findings in a 2 1/2 year old girl with an unusual mosaic karyotype. Amniocentesis was performed at 35 weeks because of intrauterine growth retardation. The in situ cultures showed 47,XX,+15 in seven colonies, 69,XXX in four colonies, and in two colonies 46,XX was detected. Subcultures showed 69,XXX/47,XX,+15 with no normal cells. A small dysmorphic baby was born at term. Cytogenetic studies were performed on cord blood, amnion, and placental tissue immediately after birth and further studies on peripheral blood, bone marrow, muscle biopsy, and skin cultures at 1 1/2 years of age. FISH with two autosomal centromeric probes was performed on the peripheral blood sample. A normal cell line could not be seen in any postnatal tissue by either technique. The predominant cell line postnatally was 69,XXX. There were no cytogenetic polymorphisms and the parental origin of the different cell lines was not determined. Marked red cell macrocytosis of peripheral blood was noted on routine blood count. Bone marrow aspiration showed megaloblastic haemopoiesis without evidence of vitamin B12 or folate deficiency. At 2 1/2 years, the patient has significant developmental problems. Images PMID:9132499

  20. Long-distance entanglement and quantum teleportation in XX spin chains

    SciTech Connect

    Campos Venuti, L.; Giampaolo, S. M.; Illuminati, F.; Zanardi, P.

    2007-11-15

    Isotropic XX models of one-dimensional spin-1/2 chains are investigated with the aim to elucidate the formal structure and the physical properties that allow these systems to act as channels for long-distance, high-fidelity quantum teleportation. We introduce two types of models: (i) open, dimerized XX chains, and (ii) open XX chains with small end bonds. For both models we obtain the exact expressions for the end-to-end correlations and the scaling of the energy gap with the length of the chain. We determine the end-to-end concurrence and show that model (i) supports true long-distance entanglement at zero temperature, while model (ii) supports 'quasi-long-distance' entanglement that slowly falls off with the size of the chain. Due to the different scalings of the gaps, respectively exponential for model (i) and algebraic in model (ii), we demonstrate that the latter allows for efficient qubit teleportation with high fidelity in sufficiently long chains even at moderately low temperatures.

  1. Overrepresentation of the ACTN3 XX genotype in elite canoe and kayak paddlers.

    PubMed

    Orysiak, Joanna; Sitkowski, Dariusz; Zmijewski, Piotr; Malczewska-Lenczowska, Jadwiga; Cieszczyk, Pawel; Zembron-Lacny, Agnieszka; Pokrywka, Andrzej

    2015-04-01

    The aim of the study was to examine the association between the ACTN3 R577X polymorphism in canoe sprint athletes (canoe and kayak paddlers) and their results at 200- or 1000-m distance. Eighty-six European white male athletes divided into 2 groups-successful, who were outstanding at national championships, and nonsuccessful in these competitions-and 354 nonathletic controls were included in this study. The R577X polymorphism of ACTN3 was typed using PCR-RFLP. ACTN3 genotype distribution among all tested athletes and controls was in Hardy-Weinberg equilibrium. The odds ratio (OR) for successful 1000-m athletes harboring the XX genotype compared with sedentary controls was 2.95 (95% confidence interval [CI]: 1.37-6.35), but the OR for nonsuccessful 200-m athletes having the XX genotype compared with controls was 2.64 (95% CI: 1.30-5.36). These results suggest that factors associated with the ACTN3 XX genotype in canoe and kayak paddlers might provide some competitive advantage in performance at 1000 m, but it seems to limit at 200 m. Further studies aimed at development of training strategies based on genetic factors are needed.

  2. Identification of SOX3 as an XX male sex reversal gene in mice and humans

    PubMed Central

    Sutton, Edwina; Hughes, James; White, Stefan; Sekido, Ryohei; Tan, Jacqueline; Arboleda, Valerie; Rogers, Nicholas; Knower, Kevin; Rowley, Lynn; Eyre, Helen; Rizzoti, Karine; McAninch, Dale; Goncalves, Joao; Slee, Jennie; Turbitt, Erin; Bruno, Damien; Bengtsson, Henrik; Harley, Vincent; Vilain, Eric; Sinclair, Andrew; Lovell-Badge, Robin; Thomas, Paul

    2010-01-01

    Sex in mammals is genetically determined and is defined at the cellular level by sex chromosome complement (XY males and XX females). The Y chromosome–linked gene sex-determining region Y (SRY) is believed to be the master initiator of male sex determination in almost all eutherian and metatherian mammals, functioning to upregulate expression of its direct target gene Sry-related HMG box–containing gene 9 (SOX9). Data suggest that SRY evolved from SOX3, although there is no direct functional evidence to support this hypothesis. Indeed, loss-of-function mutations in SOX3 do not affect sex determination in mice or humans. To further investigate Sox3 function in vivo, we generated transgenic mice overexpressing Sox3. Here, we report that in one of these transgenic lines, Sox3 was ectopically expressed in the bipotential gonad and that this led to frequent complete XX male sex reversal. Further analysis indicated that Sox3 induced testis differentiation in this particular line of mice by upregulating expression of Sox9 via a similar mechanism to Sry. Importantly, we also identified genomic rearrangements within the SOX3 regulatory region in three patients with XX male sex reversal. Together, these data suggest that SOX3 and SRY are functionally interchangeable in sex determination and support the notion that SRY evolved from SOX3 via a regulatory mutation that led to its de novo expression in the early gonad. PMID:21183788

  3. Impacts of shaking Bengkulus seismicity to subsurface Wellbore in the XX area

    NASA Astrophysics Data System (ADS)

    Rusli, Saifatur; Pratama, M. Ardian; Mardiyan, Hilman; Mirza, Finisha, Brian

    2016-05-01

    Bengkulu earthquake was happened on Wednesday, May 5th 2010 at 23:29:03 WIB (UTC-7) with magnitude 6.5 Richter scale. The Epicentrum was very close to Mentawai Fault System located on latitude 4.063°S and longitude 101.085°E with depth subsurface 27 kms. It was occurred the result of the Indian Ocean Plate-Australia's activity with low angled-subducted beneath the island of Sumatra. Shaking Bengkulus seismicity impacted subsurface in the XX Area which situated on South Palembang Sub-Basin part of South Sumatra Basin (SSB) about 200 kms far away from the epicentrum. Due to XX Area has some producing wells so that the seismicity activities as hypothetically impacts to Subsurface Wellbore which has caused some wells casing problems in the same depth. The wells casing problem shown after conducted routine sand bailer by Sand Line Unit, it was a downhole device used to remove debris sands or similar small particles around the fishingnecks of downhole tools or equipment in the wellbore, and then Sand Bailer tools got scratch at one side body. Similarly, Sand Bailer tools couldnt lowered until Total Depth and got samples sands slightly. At the end, it has impacted to well performance to produce oil in the XX Area.

  4. End-stage renal disease and primary hypogonadism associated with a 46,XX karyotype.

    PubMed

    Bailey, W A; Zwingman, T A; Reznik, V M; Griswold, W R; Mendoza, S A; Jones, K L; Freidenberg, G R

    1992-10-01

    To determine the cause of absent sexual development in a 17-year-old girl with end-stage renal disease. Case study. Seventeen-year-old girl with end-stage renal failure. None. The patient had phenotypically normal external female genitalia, müllerian duct hypoplasia, and no ovaries. Her serum gonadotropin levels were in the castrate range at baseline and after gonadotropin-releasing hormone stimulation. Her karyotype, in lymphocytes and cultured fibroblasts, was 46,XX. Analysis of genomic DNA, following polymerase chain reaction-amplication with oligonucleotide primers corresponding to the Y-encoded zinc finger protein ZFY and the testis-determining SRY gene, showed Y chromosome material in a male control but none in the patient. The results suggest a diagnosis of Frasier syndrome, a disorder characterized by true gonadal dysgenesis and end-stage renal disease occurring in normal phenotypic girls. Although previously reported only in individuals with a 46,XX karyotype, our studies indicate that Frasier syndrome may also occur in 46,XX girls. Delayed puberty is not uncommon in renal failure. This case illustrates the importance of measuring gonadotropin levels in teenage girls with delayed puberty and renal failure, particularly if the origin of the renal disease is obscure.

  5. Expression of selected genes escaping from X inactivation in the 41, XX(Y)* mouse model for Klinefelter's syndrome.

    PubMed

    Werler, Steffi; Poplinski, Andreas; Gromoll, Jörg; Wistuba, Joachim

    2011-06-01

    We hypothesized that patients with Klinefelter's syndrome (KS) not only undergo X inactivation, but also that genes escape from inactivation. Their transcripts would constitute a significant difference, as male metabolism is not adapted to a 'female-like' gene dosage. We evaluated the expression of selected X-linked genes in our 41, XX(Y)* male mice to determine whether these genes escape inactivation and whether tissue-specific differences occur. Correct X inactivation was identified by Xist expression. Relative expression of X-linked genes was examined in liver, kidney and brain tissue by real-time PCR in adult XX(Y)* and XY* males and XX females. Expression of genes known to escape X inactivation was analysed. Relative mRNA levels of Pgk1 (control, X inactivated), and the genes Eif2s3x, Kdm5c, Ddx3x and Kdm6a escaping from X inactivation were quantified from liver, kidney and brain. Pgk1 mRNA expression showed no difference, confirming correct X inactivation. In kidney and liver, XX(Y)* males resembled the female expression pattern in all four candidate genes and were distinguishable from XY* males. Contrastingly, in brain tissue XX(Y)* males expressed all four genes higher than male and female controls. Altered expression of genes escaping X inactivation probably contributes directly to the XX(Y)* phenotype. © 2011 The Author(s)/Acta Paediatrica © 2011 Foundation Acta Paediatrica.

  6. Wide spectrum of NR5A1-related phenotypes in 46,XY and 46,XX individuals.

    PubMed

    Domenice, Sorahia; Zamboni Machado, Aline; Moraes Ferreira, Frederico; Ferraz-de-Souza, Bruno; Marcondes Lerario, Antonio; Lin, Lin; Yumie Nishi, Mirian; Lisboa Gomes, Nathalia; Evelin da Silva, Thatiana; Barbosa Silva, Rosana; Vieira Correa, Rafaela; Ribeiro Montenegro, Luciana; Narciso, Amanda; Maria Frade Costa, Elaine; C Achermann, John; Bilharinho Mendonca, Berenice

    2016-12-01

    Steroidogenic factor 1 (NR5A1, SF-1, Ad4BP) is a transcriptional regulator of genes involved in adrenal and gonadal development and function. Mutations in NR5A1 have been among the most frequently identified genetic causes of gonadal development disorders and are associated with a wide phenotypic spectrum. In 46,XY individuals, NR5A1-related phenotypes may range from disorders of sex development (DSD) to oligo/azoospermia, and in 46,XX individuals, from 46,XX ovotesticular and testicular DSD to primary ovarian insufficiency (POI). The most common 46,XY phenotype is atypical or female external genitalia with clitoromegaly, palpable gonads, and absence of Müllerian derivatives. Notably, an undervirilized external genitalia is frequently seen at birth, while spontaneous virilization may occur later, at puberty. In 46,XX individuals, NR5A1 mutations are a rare genetic cause of POI, manifesting as primary or secondary amenorrhea, infertility, hypoestrogenism, and elevated gonadotropin levels. Mothers and sisters of 46,XY DSD patients carrying heterozygous NR5A1 mutations may develop POI, and therefore require appropriate counseling. Moreover, the recurrent heterozygous p.Arg92Trp NR5A1 mutation is associated with variable degrees of testis development in 46,XX patients. A clear genotype-phenotype correlation is not seen in patients bearing NR5A1 mutations, suggesting that genetic modifiers, such as pathogenic variants in other testis/ovarian-determining genes, may contribute to the phenotypic expression. Here, we review the published literature on NR5A1-related disease, and discuss our findings at a single tertiary center in Brazil, including ten novel NR5A1 mutations identified in 46,XY DSD patients. The ever-expanding phenotypic range associated with NR5A1 variants in XY and XX individuals confirms its pivotal role in reproductive biology, and should alert clinicians to the possibility of NR5A1 defects in a variety of phenotypes presenting with gonadal dysfunction

  7. SU-E-T-472: Improvement of IMRT QA Passing Rate by Correcting Angular Dependence of MatriXX

    SciTech Connect

    Chen, Q; Watkins, W; Kim, T; Neal, B

    2015-06-15

    Purpose: Multi-channel planar detector arrays utilized for IMRT-QA, such as the MatriXX, exhibit an incident-beam angular dependent response which can Result in false-positive gamma-based QA results, especially for helical tomotherapy plans which encompass the full range of beam angles. Although MatriXX can use with gantry angle sensor to provide automatically angular correction, this sensor does not work with tomotherapy. The purpose of the study is to reduce IMRT-QA false-positives by correcting for the MatriXX angular dependence. Methods: MatriXX angular dependence was characterized by comparing multiple fixed-angle irradiation measurements with corresponding TPS computed doses. For 81 Tomo-helical IMRT-QA measurements, two different correction schemes were tested: (1) A Monte-Carlo dose engine was used to compute MatriXX signal based on the angular-response curve. The computed signal was then compared with measurement. (2) Uncorrected computed signal was compared with measurements uniformly scaled to account for the average angular dependence. Three scaling factor (+2%, +2.5%, +3%) were tested. Results: The MatriXX response is 8% less than predicted for a PA beam even when the couch is fully accounted for. Without angular correction, only 67% of the cases pass the >90% points γ<1 (3%, 3mm). After full angular correction, 96% of the cases pass the criteria. Of three scaling factors, +2% gave the highest passing rate (89%), which is still less than the full angular correction method. With a stricter γ(2%,3mm) criteria, the full angular correction method was still able to achieve the 90% passing rate while the scaling method only gives 53% passing rate. Conclusion: Correction for the MatriXX angular dependence reduced the false-positives rate of our IMRT-QA process. It is necessary to correct for the angular dependence to achieve the IMRT passing criteria specified in TG129.

  8. Time-series Spectroscopy of the Pulsating Eclipsing Binary XX Cephei

    NASA Astrophysics Data System (ADS)

    Koo, Jae-Rim; Lee, Jae Woo; Hong, Kyeongsoo; Kim, Seung-Lee; Lee, Chung-Uk

    2016-03-01

    Oscillating Algol-type eclipsing binaries (oEA) are very interesting objects that have three observational features of eclipse, pulsation, and mass transfer. Direct measurement of their masses and radii from the double-lined radial velocity data and photometric light curves would be the most essential for understanding their evolutionary process and for performing the asteroseismological study. We present the physical properties of the oEA star XX Cep from high-resolution time-series spectroscopic data. The effective temperature of the primary star was determined to be 7946 ± 240 K by comparing the observed spectra and the Kurucz models. We detected the absorption lines of the secondary star, which had never been detected in previous studies, and obtained the radial velocities for both components. With the published BVRI light curves, we determined the absolute parameters for the binary via Wilson-Devinney modeling. The masses and radii are {M}1=2.49+/- 0.06 {M}⊙ , {M}2=0.38+/- 0.01 {M}⊙ , {R}1=2.27+/- 0.02 {R}⊙ , and {R}2=2.43+/- 0.02 {R}⊙ , respectively. The primary star is about 45% more massive and 60% larger than the zero-age main sequence stars with the same effective temperature. It is probably because XX Cep has experienced a very different evolutionary process due to mass transfer, contrasting with the normal main sequence stars. The primary star is located inside the theoretical instability strip of δ Sct-type stars on the HR diagram. We demonstrated that XX Cep is an oEA star, consisting of a δ Sct-type pulsating primary component and an evolved secondary companion.

  9. Mosaic double aneuploidy (45,X/47,XX,+8) with aortic dissection.

    PubMed

    Lee, M N; Choi, K H; Kim, D K; Kim, S H

    2014-01-01

    Chromosomal aneuploidy is considerably frequent and may involve either autosomes or sex chromosomes. While double aneuploidy involving both autosomal and sex chromosomes is rare, several reports described the cases of sex chromosomal aneuploidies in combination with trisomy 21, such as Down-Klinefelter and Down-Turner syndrome. However, trisomy 8-Turner syndrome has been rarely described to date. Here we report a case of a 28-year-old female with mosaic trisomy 8-Turner syndrome. The patient was referred to our hospital for aortic dissection. On physical evaluation, features of her phenotype, which included short stature, webbed neck and cubitus valgus, suggested congenital anomalies such as Turner syndrome. Chest CT revealed aortic dissection with bicuspid aortic valve and coarctation. G-banding cytogenetic analysis of peripheral blood showed mosaicism with two cell lines (45,X[17]/47,XX,+8[33]). FISH analysis indicated that 15% of the cells were of monosomy X karyotype and 85% of the cells were with XX karyotype and trisomy 8 was detected only in XX cells. Though the patient exhibited clinical features of Turner syndrome, somatic stigmas present were not clearly distinguishable from those of trisomy 8, such as short stature, skeletal and cardiac abnormalities. Observations from most of the double aneuploidy cases indicated that the patient's phenotype was not necessarily in correlation to the ratio of autosomal and sex chromosomal aberrations. Mosaicism in trisomy 8-Turner syndrome was rarely documented and we believe this is the first reported case of mosaicism in trisomy 8-Turner syndrome presenting with aortic dissection and surviving into adulthood.

  10. Mapping between the Heisenberg XX Spin Chain and Low-Energy QCD

    NASA Astrophysics Data System (ADS)

    Pérez-García, David; Tierz, Miguel

    2014-04-01

    By using random matrix models, we uncover a connection between the low-energy sector of four-dimensional QCD at finite volume and the Heisenberg XX model in a 1D spin chain. This connection allows us to relate crucial properties of QCD with physically meaningful properties of the spin chain, establishing a dictionary between both worlds. For the spin chain, we predict a third-order phase transition and a Tracy-Widom law in the transition region. We also comment on possible numerical implications of the connection as well as on possible experimental implementations.

  11. Skin pigment anomalies and mosaicism for a double autosomal trisomy (48,XX,+18,+20).

    PubMed

    Devriendt, K; Matthijs, G; Meireleire, J; Roelen, L; van Buggenhout, G; Fryns, J P

    1998-01-01

    We present a patient with profound mental retardation, epilepsy, facial dysmorphism and multiple skin hyper- and depigmentation areas. Karyotype in white blood cells was normal female, whereas in cultured skin fibroblasts originating from a depigmentated area, mosaic 48,XX,+18,+20 was found. Molecular analyses using polymorphic microsatellites showed a different origin of both additional chromosomes: maternal for the chromosome 20, paternal for chromosome 18. This, together with a mosaic state is consistent with a double postzygotic error in chromosome segregation possibly occurring in a single cell division.

  12. High reliability and high performance of 9xx-nm single emitter laser diodes

    NASA Astrophysics Data System (ADS)

    Bao, L.; Leisher, P.; Wang, J.; Devito, M.; Xu, D.; Grimshaw, M.; Dong, W.; Guan, X.; Zhang, S.; Bai, C.; Bai, J. G.; Wise, D.; Martinsen, R.

    2011-03-01

    Improved performance and reliability of 9xx nm single emitter laser diodes are presented. To date, over 15,000 hours of accelerated multi-cell lifetest reliability data has been collected, with drive currents from 14A to 18A and junction temperatures ranging from 60°C to 110°C. Out of 208 devices, 14 failures have been observed so far. Using established accelerated lifetest analysis techniques, the effects of temperature and power acceleration are assessed. The Mean Time to Failure (MTTF) is determined to be >30 years, for use condition 10W and junction temperature 353K (80°C), with 90% statistical confidence.

  13. Analysis of low-density effects in suborbital flight of FAST20XX

    NASA Astrophysics Data System (ADS)

    Votta, Raffaele; Marini, Marco; Morsa, Luigi; Fels, Giorgio; Zuppardi, Gennaro; Schwanekamp, Tobias; Sippel, Martin

    2012-11-01

    The paper studies the high altitude effects to the future hypersonic/suborbital re-entry vehicle SpaceLiner developed in the framework of EC-funded FAST20XX project. Bridging functions have been developed and validated by means of DSMC calculations. The effects of rarefaction on global longitudinal aerodynamics of SpaceLiner in the range of altitude 65÷85 km have been pointed out by comparing to the aerodatabase in continuum regime conditions. DSMC computation has been done in the higher SpaceLiner altitude point confirming the bridging function results and providing heat transfer estimations.

  14. Presumptive mosaic origin of an XX/XY female with ambiguous genitalia.

    PubMed Central

    Zuffardi, O; Gargantini, L; Lambiase, S; Lo Curto, F; Maraschio, P; Ford, C E

    1987-01-01

    A child with ambiguous genitalia had an XX/XY karyotype in all tissues examined. Analyses of 11 informative polymorphisms, both chromosomal and genetic (Rh and HLA), showed no difference between the two cell lines. It is unlikely that the child originated from fertilisation of the egg and the second polar body by two sperms; therefore, we hypothesise that the child originated from an XXY zygote after mitotic errors during cleavage. Recent findings of differences in the chromosome constitution between the extra-embryonic tissues and the fetus support this view. PMID:3573003

  15. 46,XX patients with congenital adrenal hyperplasia: initial assignment as male, reassigned female.

    PubMed

    Lee, Peter A; Witchel, Selma F

    2005-02-01

    Six 46,XX patients with congenital adrenal hyperplasia (CAH) presented with genital ambiguity, five so severe that initial gender assignment was male. Once diagnosis was realized, parents were involved in evaluation and chose sex re-assignment as female. To date, these girls and their parents all indicate satisfaction with their decision for a female sex of rearing. The girls have a female gender identity with behavior characteristics known for females with CAH. Thus, while outcome is satisfactory, it is realized that for most, expression of sexual orientation and adult life adjustments have not yet occurred.

  16. Klinefelter's syndrome in nontwin brothers and maternal XX/XXX mosaicism.

    PubMed

    Lodi, A; Monti, D; Gaspari, G; Ravaglia, G; Guadagni, C; Businello, M; Lamedica, R; Lenzi, S

    1979-01-01

    A case of two nontwin brothers, 19 and 17 years old, who had both Klinefelter's syndrome with a chromosomal mosaicism 46 XY/47 XXY, is reported here. The analysis of their mother's karyotype revealed a 46 XX/47 XXX mosaicism. It is hypothesized that the presence of an extra X chromosome in all three subjects could depend on the transmission of two X chromosomes from the mother to the sons or, less likely, on an increased liability to nondisjunction of the X chromosomes during one of the early mitotic divisions in the zygotes.

  17. Refining the regulatory region upstream of SOX9 associated with 46,XX testicular disorders of Sex Development (DSD).

    PubMed

    Hyon, Capucine; Chantot-Bastaraud, Sandra; Harbuz, Radu; Bhouri, Rakia; Perrot, Nicolas; Peycelon, Matthieu; Sibony, Mathilde; Rojo, Sandra; Piguel, Xavier; Bilan, Frederic; Gilbert-Dussardier, Brigitte; Kitzis, Alain; McElreavey, Ken; Siffroi, Jean-Pierre; Bashamboo, Anu

    2015-08-01

    Disorders of Sex Development (DSD) are a heterogeneous group of disorders affecting gonad and/or genito-urinary tract development and usually the endocrine-reproductive system. A genetic diagnosis is made in only around 20% of these cases. The genetic causes of 46,XX-SRY negative testicular DSD as well as ovotesticular DSD are poorly defined. Duplications involving a region located ∼600 kb upstream of SOX9, a key gene in testis development, were reported in several cases of 46,XX DSD. Recent studies have narrowed this region down to a 78 kb interval that is duplicated or deleted respectively in 46,XX or 46,XY DSD. We identified three phenotypically normal patients presenting with azoospermia and 46,XX testicular DSD. Two brothers carried a 83.8 kb duplication located ∼600 kb upstream of SOX9 that overlapped with the previously reported rearrangements. This duplication refines the minimal region associated with 46,XX-SRY negative DSD to a 40.7-41.9 kb element located ∼600 kb upstream of SOX9. Predicted enhancer elements and evolutionary-conserved binding sites for proteins known to be involved in testis determination are located within this region.

  18. Application of arm-specific painting probes of horse X chromosome for karyotype analysis in an infertile Hutsul mare with 64,XX/65,XX+Xp karyotype: case report.

    PubMed

    Bugno, Monika; Słota, Ewa

    2007-09-01

    A 5-year-old infertile Hutsul mare was subjected to cytogenetic analysis. Fluorescence in situ hybridisation (FISH) using the equine Xp and Xq chromosome painting probes was carried out on chromosome preparations obtained after blood lymphocyte culture. These probes were generated by chromosome microdissection and a large number of spreads was analysed (525). The karyotype formula of the analysed mare was 64,XX/65,XX+Xp with the ratio of the two lines being 99.4 and 0.6, respectively. The goal of the study was to apply chromosome microdissection and the FISH technique for cytogenetic diagnostics.

  19. First description of scrotal testicles in a dog affected by 78, XX testicular disorder of sex development.

    PubMed

    Del Carro, A P; Rosset, E; Josson-Schramme, A; Lambert, V; Buff, S

    2014-10-01

    An eight-month-old female dog presented with ambiguous external genitalia. A thorough clinical examination together with various imaging techniques and a histology examination showed the presence of two testicles linked to both the Mullerian and Wolffian ducts. The discovery of the 78,XX SRY-negative karyotype led to the diagnosis of incoherence between the chromosomal and gonadal sex, which is typical for a 78,XX testicular disorder of sex development. Our case was unique because the testicles were still located in their normal scrotal position, whereas the literature contains reports of the presence of cryptorchid testicles in this karyotype setting. To our knowledge, this is the first case that describes an SRY-negative 78,XX testicular disorder of sex development with bilateral scrotal testicles. © 2014 Blackwell Verlag GmbH.

  20. Evolution of Dosage Compensation in Anolis carolinensis, a Reptile with XX/XY Chromosomal Sex Determination

    PubMed Central

    Rupp, Shawn M.; Webster, Timothy H.; Olney, Kimberly C.; Hutchins, Elizabeth D.; Kusumi, Kenro

    2017-01-01

    In species with highly heteromorphic sex chromosomes, the degradation of one of the sex chromosomes will result in unequal gene expression between the sexes (e.g. between XX females and XY males) and between the sex chromosomes and the autosomes. Dosage compensation is a process whereby genes on the sex chromosomes achieve equal gene expression. We compared genome-wide levels of transcription between males and females, and between the X chromosome and the autosomes in the green anole, Anolis carolinensis. We present evidence for dosage compensation between the sexes, and between the sex chromosomes and the autosomes. When dividing the X chromosome into regions based on linkage groups, we discovered that genes in the first reported X-linked region, anole linkage group b (LGb), exhibit complete dosage compensation, although the rest of the X-linked genes exhibit incomplete dosage compensation. Our data further suggest that the mechanism of this dosage compensation is upregulation of the X chromosome in males. We report that approximately 10% of coding genes, most of which are on the autosomes, are differentially expressed between males and females. In addition, genes on the X chromosome exhibited higher ratios of nonsynonymous to synonymous substitution than autosomal genes, consistent with the fast-X effect. Our results from the green anole add an additional observation of dosage compensation in a species with XX/XY sex determination. PMID:28206607

  1. Congenital adrenal hyperplasia: surgical considerations required to repair a 46,XX patient raised as a boy.

    PubMed

    Dasgupta, Roshni; Schnitzer, J Jay; Hendren, W Hardy; Donahoe, Patricia K

    2003-08-01

    21-hydroxylase deficiency (P450 CYP21) accounts for 90% of cases of congenital adrenal hyperplasia (CAH), which is associated with abnormally low cortisol and high production of androgen precursors and is the most common cause of ambiguous genitalia. Increased androgen causes in utero virilization of the fetus, consisting of clitoral enlargement, an urogenital sinus, and labioscrotal enlargement and fusion. This is the first case in an experience covering more than 30 years, of a 46,XX patient raised as a boy. The authors report a case of a Pakistani patient born of a consanguineous union, who came to medical attention at age 3 because of severe genital ambiguity; genetic analyses showed that the child was a compound heterozygote for CAH. The surgical management of this patient consisted of (1) staged hypospadias repairs preceded by testosterone therapy, (2) creation of a bladder graft neourethra, (3) removal of müllerian structures, (4) correction of bifid prepenile scrotum, and (5) insertion of testicular prostheses. The commitment to raise a 46,XX child as a boy is a very rare event. With a series of staged complex surgical procedures and careful steroid replacement, normal secondary sexual characteristics can be achieved in these children.

  2. Bilateral Ovotestes in a 78, XX SRY-Negative Beagle Dog.

    PubMed

    Pérez-Gutiérrez, José F; Monteagudo, Luís V; Rodríguez-Bertos, Antonio; García-Pérez, Enrique; Sánchez-Calabuig, María J; García-Botey, Concepción; Whyte, Ana; de la Muela, Mercedes Sánchez

    2015-01-01

    This report describes a disorder of the sexual development in a beagle dog resulting in an intersex condition. A 6 mo old beagle was presented for evaluation of a protruding structure from the vulva consistent with an enlarged clitoris. Ultrasonographic examination revealed the presence of both gonadal and uterine structures. Retrograde cystourethrovaginogram showed the presence of an os clitoris and severe vaginal stenosis. Histological studies revealed the presence of bilateral ovotestes and uterus. The gonad had interstitial cells within seminiferous-like tubules lined only with Sertoli cells and abundant interstitial cells among primordial, primary, and secondary follicles. Hormone assays completed before and after gonadohysterectomy showed an elevation in the levels of progesterone and dihydrotestosterone that returned to baseline 3 mo after surgery. Testosterone levels that were within the male reference ranges before surgery decreased to basal levels postsurgically. 17-β-Estradiol levels showed little variation and values were always within the reference ranges for a male. Cytogenetic analysis showed a normal female karyotype (2n = 78, XX) and polymerase chain reaction analysis revealed the absence of the sex-determining region Y gene. In summary, the dog presented bilateral ovotestes and a 2n = 78, XX chromosomal complement lacking the sex determining region Y gene, consistent with a diagnosis of true hermaphroditism.

  3. Non-Markovian dynamics in the extended cluster spin-1/2 XX chain

    NASA Astrophysics Data System (ADS)

    Mahmoudi, M.; Mahdavifar, S.; Zadeh, T. Mohammad Ali; Soltani, M. R.

    2017-01-01

    We study the dynamics of entanglement, mutual information, and quantum discord in the extended cluster spin-1/2 XX chain, equivalent to a one-dimensional spin-1/2 XX model with three-spin interaction (TSI). Selecting the nearest neighbor pair spins as an open quantum system, the rest of the chain plays the role of the environment. The two-point Heisenberg and the TSI are responsible for coupling between the system and the environment. Although the revival phenomenon of quantum correlations as an indication of non-Markovian dynamics is observed for TSI stronger than the Heisenberg interaction, the study of the trace distance has proven that the dynamical phase transition from the Markovian to the non-Markovian regime happens at a critical value where the TSI is equal to half of the Heisenberg interaction. By focusing on the nearest neighbor pair spins of the environment, we have also shown that the dynamics of quantum correlation in the environment is sensitive to Markovian and non-Markovian regions.

  4. Spurious case of XX maleness in a patient with a history of Wiskott-Aldrich syndrome.

    PubMed

    Nebesio, Todd D; Torres-Martinez, Wilfredo; Rink, Richard C; Eugster, Erica A

    2011-01-01

    To alert endocrinologists about the potential for karyotype confusion in patients who have undergone bone marrow transplantation. Clinical, laboratory, and imaging data are reported on a young adult male patient who initially presented because of concerns about short stature. An 18-year-old fully virilized male patient with a history of Wiskott-Aldrich syndrome had undergone successful bone marrow transplantation in infancy. The donor was his older sister. Many years later, he underwent evaluation because of short stature and was found to have a 46, XX karyotype. This unexpected finding led to several costly laboratory and imaging studies, as well as a new diagnosis of a disorder of sex development. The patient was referred to our medical center for further evaluation of XX sex reversal. A skin biopsy was eventually performed, which revealed a 46, XY karyotype. This unusual case highlights the fact that a peripheral blood specimen from bone marrow transplant recipients reflects the genetic makeup of the bone marrow donor. Although the cytogenetic changes that occur in recipients of bone marrow transplants are well known to hematologists and oncologists, they are not commonly recognized by other health care providers. Increased awareness of this potential situation in long-term survivors of bone marrow transplantation is needed.

  5. High Temperature Increases the Masculinization Rate of the All-Female (XX) Rainbow Trout “Mal” Population

    PubMed Central

    Valdivia, Karina; Jouanno, Elodie; Volff, Jean-Nicolas; Galiana-Arnoux, Delphine; Guyomard, René; Helary, Louise; Mourot, Brigitte; Fostier, Alexis; Quillet, Edwige; Guiguen, Yann

    2014-01-01

    Salmonids are generally considered to have a robust genetic sex determination system with a simple male heterogamety (XX/XY). However, spontaneous masculinization of XX females has been found in a rainbow trout population of gynogenetic doubled haploid individuals. The analysis of this masculinization phenotype transmission supported the hypothesis of the involvement of a recessive mutation (termed mal). As temperature effect on sex differentiation has been reported in some salmonid species, in this study we investigated in detail the potential implication of temperature on masculinization in this XX mal-carrying population. Seven families issued from XX mal-carrying parents were exposed from the time of hatching to different rearing water temperatures ((8, 12 and 18°C), and the resulting sex-ratios were confirmed by histological analysis of both gonads. Our results demonstrate that masculinization rates are strongly increased (up to nearly two fold) at the highest temperature treatment (18°C). Interestingly, we also found clear differences between temperatures on the masculinization of the left versus the right gonads with the right gonad consistently more often masculinized than the left one at lower temperatures (8 and 12°C). However, the masculinization rate is also strongly dependent on the genetic background of the XX mal-carrying families. Thus, masculinization in XX mal-carrying rainbow trout is potentially triggered by an interaction between the temperature treatment and a complex genetic background potentially involving some part of the genetic sex differentiation regulatory cascade along with some minor sex-influencing loci. These results indicate that despite its rather strict genetic sex determinism system, rainbow trout sex differentiation can be modulated by temperature, as described in many other fish species. PMID:25501353

  6. SU-E-T-778: Use of the 2D MatriXX Detector for Measuring Scanned Ion Beam Parameters

    SciTech Connect

    Anvar, M Varasteh; Monaco, V; Sacchi, R; Guarachi, L Fanola; Cirio, R; Giordanengo, S; Marchetto, F; Vignati, A; Donetti, M; Ciocca, M; Panizza, D

    2015-06-15

    Purpose: The quality assurance (QA) procedure has to check the most relevant beam parameters to ensure the delivery of the correct dose to patients. Film dosimetry, which is commonly used for scanned ion beam QA, does not provide immediate results. The purpose of this work is to answer whether, for scanned ion beam therapy, film dosimetry can be replaced with the 2D MatriXX detector as a real-time tool. Methods: MatriXX, equipped with 32×32 parallel plate ion-chambers, is a commercial device intended for pre-treatment verification of conventional radiation therapy.The MatriXX, placed at the isocenter, and GAFCHROMIC films, positioned on the MatriXX entrance, were exposed to 131.44 MeV proton and 221.45 MeV/u Carbon-ion beams.The OmniPro-I’mRT software, applied for the data taking of MatriXX, gives the possibility of acquiring consecutive snapshots. Using the NI LabVIEW, the data from snapshots were logged as text files for further analysis. Radiochromic films were scanned with EPSON scanner and analyzed using software programs developed in-house for comparative purposes. Results: The field dose uniformity, flatness, beam position and beam width were investigated. The field flatness for the region covering 6×6 cm{sup 2} square field was found to be better than 2%. The relative standard deviations, expected to be constant over 2×2, 4×4 and 6×6 pixels from MatriXX measurement gives a uniformity of 1.5% in good agreement with the film results.The beam center position is determined with a resolution better than 200 µm for Carbon and less than 100 µm for proton beam.The FWHM determination for a beam wider than 10 mm is satisfactory, whilst for smaller beams the determination is uncertain. Conclusion: Precise beam position and fast 2D dose distribution can be determined in real-time using MatriXX detector. The results show that MatriXX is quick and accurate enough to be used in charged-particle therapy QA.

  7. 49 CFR 1242.74 - Adjusting and transferring loads, and car loading devices and grain doors (accounts XX-33-71 and...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Adjusting and transferring loads, and car loading devices and grain doors (accounts XX-33-71 and XX-33-72). 1242.74 Section 1242.74 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) ACCOUNTS, RECORDS AND...

  8. 49 CFR 1242.74 - Adjusting and transferring loads, and car loading devices and grain doors (accounts XX-33-71 and...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Adjusting and transferring loads, and car loading devices and grain doors (accounts XX-33-71 and XX-33-72). 1242.74 Section 1242.74 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) ACCOUNTS, RECORDS AND...

  9. 49 CFR 1242.74 - Adjusting and transferring loads, and car loading devices and grain doors (accounts XX-33-71 and...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Adjusting and transferring loads, and car loading devices and grain doors (accounts XX-33-71 and XX-33-72). 1242.74 Section 1242.74 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) ACCOUNTS, RECORDS AND...

  10. 49 CFR 1242.74 - Adjusting and transferring loads, and car loading devices and grain doors (accounts XX-33-71 and...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Adjusting and transferring loads, and car loading devices and grain doors (accounts XX-33-71 and XX-33-72). 1242.74 Section 1242.74 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) ACCOUNTS, RECORDS AND...

  11. 49 CFR 1242.51 - Dismantling retired property and depreciation (accounts XX-27-39 and 62-27-00).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Dismantling retired property and depreciation (accounts XX-27-39 and 62-27-00). 1242.51 Section 1242.51 Transportation Other Regulations Relating to... FOR RAILROADS 1 Operating Expenses-Equipment § 1242.51 Dismantling retired property and...

  12. 49 CFR 1242.37 - Dismantling retired property and depreciation (accounts XX-26-39 and 62-26-00).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Dismantling retired property and depreciation (accounts XX-26-39 and 62-26-00). 1242.37 Section 1242.37 Transportation Other Regulations Relating to... FOR RAILROADS 1 Operating Expenses-Equipment § 1242.37 Dismantling retired property and...

  13. 75 FR 43165 - Information Collection; OMB Control No. 3090-00XX; FFATA Subaward and Executive Compensation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-23

    ... ADMINISTRATION Information Collection; OMB Control No. 3090-00XX; FFATA Subaward and Executive Compensation... and Executive Compensation Reporting Requirements. Public comments are particularly invited on: Whether this collection of information is necessary for the proper performance of functions of the...

  14. Magnetic and electric order in the spin-1/2 XX model with three-spin interactions

    SciTech Connect

    Thakur, Pradeep; Durganandini, P.

    2016-05-23

    We study the spin-1/2 XX model in the presence of three-spin interactions of the XZX+YZY and XZY-YZX types. We solve the problem exactly and show that there is both finite magnetization and electric polarization for low non-zero strengths of the three-spin interactions.

  15. A rare case of lateral ovotesticular disorder with Klinefelter syndrome mosaicism 46, XX/47, XXY: An unusual presentation.

    PubMed

    Talreja, Shyam M; Banerjee, Indraneel; Yadav, Sher Singh; Tomar, Vinay

    2015-01-01

    Ovotesticular disorder of sex development (OT-DSD) is a rare disorder of sexual differentiation characterized by the presence of both ovarian and testicular tissues in the same individual. It's incidence ranges from 3% to 10% of all disorder of DSD's, and the most common presentation is 46, XX followed by 46, XX/46, XY mosaicism and 46, XY. Klinefelter syndrome (KS) mosaicism 46, XX/47, XXY is extremely rare, and its association with the ovotesticular disorder is even rarer. We report an unusual case of 16-year-old with male habitus who presented with complains of cyclic hematuria. On examination, he had bilateral gynecomastia, unilateral left cryptorchidism, absent facial hair, sparse axillary hair growth, and pubic hair distribution of feminine type. The right testis was of normal size located normally in hemiscrotum and was confirmed by radio imaging. Ultrasonography and magnetic resonance imaging revealed a cystic area behind posterior half of urinary bladder. Chromosomal analysis revealed 46, XX/47, XXY mosaicism of female karyotype and KS. Histopathological report of this left side excised specimen confirmed the structures to be ovary, uterus, and fallopian tube, thus confirming our diagnosis of the lateral ovotesticular disorder. Meticulous workup combined interdisciplinary approach will lead to early diagnosis and resolve timely sex reassignment issues and also prevent consequences arising due to gonadal insufficiency.

  16. 46, XX true hermaphroditism associated with a terminal deletion of the short arm of the X chromosome

    SciTech Connect

    Barbaux, S.; Vilain, E.; McElreavey, K.

    1994-09-01

    Testes are determined by the activity of the SRY gene product encoded by the Y chromosome. Mutations in SRY can lead to XY sex reversal (XY females) and the presence of the SRY gene in some XX individuals can lead either to complete (XX males) or incomplete (XX true hermaphrodites) sex reversal. Approximately 10% of XX true hermaphrodites contain a portion of the Y chromosome, including SRY, in their genome. The etiology of the remaining cases is unestablished but may be caused by mutations in other as yet unidentied sex determining genes downstream of SRY. Here we describe an SRY-negative true hermaphrodite with a 46,X,del(X)(p21.1-pter). The patient also presented with severe mental retardation, abnormal skin pigmentation and below average height. Histological examination of the gonad revealed bilateral ovotestis. We postulate that the Xp deletion has unmasked a recessive allele on the apparently normal X chromosome generating the intersex phenotype. This observation together with recent findings of certain XY females carrying duplications of Xp21.3 suggests that there may be a loci on Xp which acts as a switch in the testis/ovarian determination pathways.

  17. 75 FR 43166 - Information Collection; OMB Control No. 3090-00XX; FSRS Registration and Prime Awardee Entity...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-23

    ... ADMINISTRATION Information Collection; OMB Control No. 3090-00XX; FSRS Registration and Prime Awardee Entity... regarding FSRS Registration and Prime Awardee Entity-Related Information Reporting Requirements. Public... performance of functions of the FSRS Registration and Prime Awardee Entity-Related Information Reporting...

  18. Exploring entropic uncertainty relation in the Heisenberg XX model with inhomogeneous magnetic field

    NASA Astrophysics Data System (ADS)

    Huang, Ai-Jun; Wang, Dong; Wang, Jia-Ming; Shi, Jia-Dong; Sun, Wen-Yang; Ye, Liu

    2017-08-01

    In this work, we investigate the quantum-memory-assisted entropic uncertainty relation in a two-qubit Heisenberg XX model with inhomogeneous magnetic field. It has been found that larger coupling strength J between the two spin-chain qubits can effectively reduce the entropic uncertainty. Besides, we observe the mechanics of how the inhomogeneous field influences the uncertainty, and find out that when the inhomogeneous field parameter b<1, the uncertainty will decrease with the decrease of the inhomogeneous field parameter b, conversely, the uncertainty will increase with decreasing b under the condition that b>1. Intriguingly, the entropic uncertainty can shrink to zero when the coupling coefficients are relatively large, while the entropic uncertainty only reduces to 1 with the increase of the homogeneous magnetic field. Additionally, we observe the purity of the state and Bell non-locality and obtain that the entropic uncertainty is anticorrelated with both the purity and Bell non-locality of the evolution state.

  19. Two XX males diagnosed in childhood. Endocrine, renal, and laboratory findings.

    PubMed Central

    Laurance, B M; Darby, C W; Vanderschueren-Lodeweyckx, M

    1976-01-01

    Two prepubertal boys with bilateral cryptorchidism were identified as 46,XX after nuclear sexing studies in several tissues. Gonadal histology and chromosome studies suggested that true hermaphroditism or mosaicism were unlikely. Xg blood grouping was informative in one patient. Accepting paternity, this suggested either that both Xs were maternal, with loss, for example, of the male determining Y chromosome, or that the paternal X chromosome did not express, probably because of a deletion, the allele for the positive Xg blood group. The patients had normal thyroid stimulating hormone reserves but subnormal responses to human chorionic gonadotrophin stimulation, and may need hormonal replacement at puberty. Both had renal anomalies. We suggest that chromosome analysis is essential when cryptorchidism, hypospadias, or microgenitalia are found and that an intravenous pyelogram is desirable. Images FIG. PMID:4036

  20. Gonadal Dysgenesis 46, XX Associated with Mayer-Rokitansky-Kuster-Hauser Syndrome: One Case Report

    PubMed Central

    Bousfiha, N.; Errarhay, S.; Saadi, H.; Ouldim, K.; Bouchikhi, C.; Banani, A.

    2010-01-01

    Introduction. The association of gonadal dysgenesis and Mayer-Rokitansky-Kuster-Hauser syndrome is very rare and appears to be coincidental, independent of chromosomal anomalies. Case Report. We report the case of a 19-year-old woman who presented primary amenorrhea and impuberism. The endocrine study revealed hypergonadotrophic hypogonadism. The karyotype was normal, 46XX. No chromosome Y was detected at the FISH analysis. Internal genitalia could not be identified on the pelvic ultrasound and pelvic MRI. Laparoscopy was undertaken and revealed concomitant ovarian dysgenesis and Mayer-Rokitansky-Kuster-Hauser syndrome. There were no other morphological malformations. Conclusion. The pathogenesis of the association of gonadal dysgenesis and Mayer Rokitansky kuster hauser syndrome is still mysterious. The treatment is based essentially on hormone substitution therapy. The fertility prognosis is unfortunately compromised. PMID:21253547

  1. Geometric Quantum Discord in the Heisenberg XX Model with Three-Spin Interactions

    NASA Astrophysics Data System (ADS)

    Xie, Yu-Xia; Liu, Jing; Sun, Yu-Hang

    2017-02-01

    Quantum discord is a resource for quantum information processing tasks, and seeking flexible ways to control it is of practical significance. We investigate the trace distance, Bures distance, and Hellinger distance geometric quantum discords (GQDs) for thermal states of the Heisenberg XX chain with three-spin interactions. The results show that both the XZX + YZY and XZY - YZX types of three-spin interactions can be used to enhance evidently the GQDs for the boundary spins of the chain. The optimal strengths of three-spin interactions for which the maximum enhancement of the GQDs are achieved are strongly dependent on the GQD measures we adopted and the number of spins in the chain.

  2. Design of one large telescope direct drive control system based on TMS320F28xx

    NASA Astrophysics Data System (ADS)

    Song, Xiao-li; Wang, Da-xing; Zhang, Chao; Zhang, Zhen-chao; Chen, Li-yan; Ren, Chang-zhi

    2014-08-01

    The mount drive control is the key technique which mostly affects astronomical telescope's resolution and its speed. However, the ultra -lower speed and the giant moment of inertia make it very difficult to be controlled. In this paper, one segmented permanent-magnet synchronous motor (PMSM), 4m diameter, is suggested for the mount driving. A method is presented to drive the motor directly, which is based on TMS320F28XX and Insulated Gate Bipolar Transistor (IGBT) , also, HEIDENHAIN tape is used to detect the absolute position of the motor together with the Hall sensor. The segmented PMSM can work stable and the mount drive can realize nice tracking performance at ultra -lower speed with this drive system.

  3. Acromegaly accompanied by Turner syndrome with 47,XXX/45,X/46,XX mosaicism.

    PubMed

    Yamazaki, Masanori; Sato, Ai; Nishio, Shin-ichi; Takeda, Teiji; Miyamoto, Takahide; Katai, Miyuki; Hashizume, Kiyoshi

    2009-01-01

    A 33-year-old woman was hospitalized for examination of edematous laryngopharynx. She was acromegalic. A pituitary adenoma with elevated serum levels of growth hormone (GH) and insulin-like growth factor-I (IGF-I) was detected, indicating acromegaly caused by GH-secreting pituitary adenoma. Multiple pigmented nevi were also noted without overt short stature and cubitus valgus. Chromosome analysis revealed that she had contracted Turner syndrome with 47,XXX/45,X/46,XX mosaicism. Transsphenoidal resection of the tumor decreased serum GH and IGF-I levels, but the edema was not improved. Both premature ovarian failure and hypertension appeared after surgery. This case may indicate the important relationships between GH/IGF-I and Turner syndrome.

  4. Aggregate model of cometary dust: an application to comet Levy 1990XX

    NASA Astrophysics Data System (ADS)

    Das, H. S.; Das, S. R.; Paul, T.; Suklabaidya, A.; Sen, A. K.

    2008-09-01

    In the present work, the light-scattering properties of comet Levy 1990XX are studied through simulations using Ballistic Particle-Cluster Aggregation (BPCA) or Ballistic Cluster-Cluster Aggregation (BCCA) aggregates of up to 128 spherical monomers of different compositions (e.g. silicates, carbonaceous materials etc.) and the best-fitting theoretical polarization curve is generated using the SUPERPOSITION T-MATRIX code. The best-fitting refractive indices coming out from the present analysis show silicate behaviour when monomer radius is am = 0.12μm and provide excellent results on the maximum and negative degrees of linear polarization at a single wavelength λ = 0.485μm for BCCA aggregates.

  5. Gender of rearing and psychosocial aspect in 46 XX congenital adrenal hyperplasia

    PubMed Central

    Gangaher, Arushi; Jyotsna, Viveka P.; Chauhan, Vasundhera; John, Jomimol; Mehta, Manju

    2016-01-01

    Background: In congenital adrenal hyperplasia (CAH) with ambiguous genitalia, assigning gender of rearing can be complex, especially If genitalia is highly virilized. Apart from karyotype, prenatal androgen exposure, patient's gender orientation, sociocultural, and parental influences play a role. The aim of this study was to assess gender dysphoria and psychosocial issues in patients of CAH raised as males and females. Materials and Methods: This is a cross-sectional study that includes patients (old and new) with CAH who were treated by us in the last 6 months. A semi-structured interview proforma was used to elicit history and psychosocial background of the patients. The clinical and biochemical details were noted. For psychological analysis, patients were screened for gender dysphoria using Parent Report Gender Identity Questionnaire for children <12 years and Gender Identity/Gender Dysphoria Questionnaire for Adolescents and Adults. Results: We analyzed 22 46 XX CAH patients among which, 3 were reared as males and 19 as females. Among the 19 patients reared as females, 17 patients showed no gender dysphoria. Two patients revealed gender dysphoria as indicated by their marginally low scores on the gender dysphoria assessment. However, in view of current literature and the age groups of the patients, behavior of the 6-year-old patient can be best understood as being tomboyish. Gender dysphoria in the 22-year-old can be explained by the dominance of psychosocial factors and not hormones alone. Among the three patients reared as males, two prepubertal were satisfied with their male gender identity. The third patient, aged 32 years, had gender dysphoria when reared as a male that resolved when gender was reassigned as female and feminizing surgery was done. Conclusion: Gender assignment in 46 XX CAH is guided by factors such as degree of virilization of genitalia, gender orientation, patient involvement, sociocultural, and parental influences. PMID:27867895

  6. Uniparental Disomy in Somatic Mosaicism 45,X/46,XY/46,XX Associated with Ambiguous Genitalia.

    PubMed

    Serra, Alexandre; Denzer, Friederike; Hiort, Olaf; Barth, Thomas F; Henne-Bruns, Doris; Barbi, Gotthold; Rettenberger, Günther; Wabitsch, Martin; Just, Walter; Leriche, Clothilde

    2015-01-01

    Disorders of sex development (DSD) affect the development of chromosomal, gonadal and/or anatomical sex. We analyzed a patient with ambiguous genitalia aiming to correlate the genetic findings with the phenotype. Blood and tissue samples from a male patient with penoscrotal hypospadias were analyzed by immunohistochemistry, karyotyping and FISH. DNA was sequenced for the AR, SRY and DHH genes, and further 26 loci in different sex chromosomes were analyzed by MLPA. The gonosomal origin was evaluated by simple tandem repeat (STR) analysis and SNP array. Histopathology revealed a streak gonad, a fallopian tube and a rudimentary uterus, positive for placental alkaline phosphatase, cytokeratin-7 and c-kit, and negative for estrogen, androgen and progesterone receptors, alpha-inhibin, alpha-1-fetoprotein, β-hCG, and oct-4. Karyotyping showed a 45,X/46,XY mosaicism, yet FISH showed both 46,XX/46,XY mosaicism (gonad and urethral plate), 46,XX (uterus and tube) and 46,XY karyotypes (rudimentary testicular tissue). DNA sequencing revealed intact sequences in SOX9, WNT4, NR0B1, NR5A1, CYP21A2, SRY, AR, and DHH. STR analysis showed only one maternal allele for all X chromosome markers (uniparental isodisomy, UPD), with a weaker SRY signal and a 4:1 ratio in the X:Y signal. Our findings suggest that the observed complex DSD phenotype is the result of somatic gonosomal mosaicism and UPD despite a normal blood karyotype. The presence of UPD warrants adequate genetic counseling for the family and frequent, lifelong, preventive follow-up controls in the patient.

  7. Research on 9xx nm diode laser for direct and pumping applications

    NASA Astrophysics Data System (ADS)

    Sebastian, J.; Hülsewede, R.; Pietrzak, A.; Zorn, M.; Wölz, M.; Meusel, J.; Schröder, M.; Wittschirk, Th.

    2015-02-01

    High-power laser bars and single emitters have proven as attractive light sources for many industrial applications such as direct material processing or as pump sources for solid state and fiber-lasers. There is also a great interest in quasi-CW laser bars for high-energy projects. These applications require a continuous improvement of laser diodes for reliable optical output powers, high electrical-to-optical efficiencies, brightness and costs. In this paper JENOPTIK presents an overview of recent research for highly efficient CW and quasi-CW laser devices emitting in a wide wavelength range between 880 nm and 1020 nm. The last research results concern the 9xx single emitters and laser arrays. The 9xx nm 12 W single emitters and 976 nm 55 W laser arrays have efficiencies above 65%. New life time tests for single emitter devices currently exceed 1300 hours of reliable operation at room temperature and over 1500 hours at 45°C. Because of the small far field distribution of the optical power, the high output power and the small near field the 55 W arrays show a brightness of 75 MW x cm-2sr-1 with 95% power content. The technology for new generation 940 nm high fill-factor bars has been currently extended to emission wavelengths of 976 nm and 1020 nm with excellent results: 200 W output power with 63% efficiency using passive cooling. The innovative design of the laser structure enables, moreover, the realization of 500 W 880 nm quasi-CW laser bars with wall-plug efficiencies of 55% and a narrow fast-axis divergence angle of 40° (95% power content).

  8. A 45,XX,-5,-14,+t(5q;14q)mat cri du chat child.

    PubMed

    Bass, H N; Sparkes, R S; Crandall, B F; Galos, K J; Howard, J

    1978-03-01

    A two-year-old girl has the following features of the cri du chat syndrome: microcephaly, hypertelorism, downward slanting of the palpebral fissures, psychomotor retardation and a cat-like cry. She is only of five patients having the cat cry syndrome with 45 chromosomes. Her karyotype is 45,XX, -5, -14, +t(5; 14)(5qter leads to 5p11: : 14q11 leads to 14qter) with the translocation inherited from her mother and maternal grandmother, each of whom is the carrier of a balanced translocation 46,XX,t(5;14)(p11q11). Normal plasma activity for hexosaminidase B suggests the locus for this enzyme is not located in the delected segment of 5 p.

  9. XX true hemaphroditism in Southern Africa blacks: Exclusion of SRY sequences and uniparental disomy of the X chromosome

    SciTech Connect

    Spurdle, A.B.; Shankman, S.; Ramsay, M.

    1995-01-02

    A molecular investigation of 16 Bantu-speaking Black XX true hermaphrodites was undertaken in an attempt to determine the cause of the disorder. Y-specific sequences, including sequences mapping to the sex-determining region of the Y, were shown to be absent from lymphocyte tissue of all 16 patients tested. Y chromosome sequences were also absent from the ovarian and testicular components of both ovotestes of a single XX true hermaphrodite, thus excluding gonadal mosaicism involving Y chromosome sequences. Since there is evidence of Xp genes involved in testis determination/differentiation, uniparental disomy of the X chromosome was investigated in 14 XXTH families. Uniparental disomy was excluded in 12 of the 14 families, and isodisomy was excluded in the remaining two cases. 29 refs., 2 tabs.

  10. Combined Leydig cell and Sertoli cell dysfunction in 46,XX males lacking the sex determining region Y gene

    SciTech Connect

    Turner, B.; Vordermark, J.S.; Fechner, P.Y.

    1995-07-03

    We have evaluated 3 individuals with a rare form of 46,XX sex reversal. All of them had ambiguous external genitalia and mixed wolffian and muellerian structures, indicating both Leydig cell and Sertoli cell dysfunction, similar to that of patients with true hermaphroditism. However, gonadal tissue was not ovotesticular but testicular with varying degrees of dysgenesis. SRY sequences were absent in genomic DNA from peripheral leukocytes in all 3 subjects. Y centromere sequences were also absent, indicating that testis development did not occur because of a low level mosaicism of Y-bearing cells. The subjects in this report demonstrate that there is a continuum in the extent of the testis determination in SRY-negative 46,XX sex reversal, ranging from nearly normal to minimal testicular development. 20 refs.

  11. 40 CFR Table 2 to Subpart Xx of... - Requirements of 40 CFR Part 61, Subpart FF, Not Included in the Requirements for This Subpart and...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Subpart XX of Part 63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Ethylene Manufacturing Process Units: Heat Exchange Systems and Waste...

  12. 40 CFR Table 2 to Subpart Xx of... - Requirements of 40 CFR Part 61, Subpart FF, Not Included in the Requirements for This Subpart and...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Subpart XX of Part 63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Ethylene Manufacturing Process Units: Heat Exchange Systems and Waste...

  13. Should male gender assignment be considered in the markedly virilized patient With 46,XX and congenital adrenal hyperplasia?

    PubMed

    Lee, Peter A; Houk, Christopher P; Husmann, Douglas A

    2010-10-01

    We assess the outcome in 46,XX men with congenital adrenal hyperplasia who were born with Prader 4 or 5 genitalia and assigned male gender at birth. After receiving institutional review board approval and subject consent we reviewed the medical records of 12 men 35 to 69 years old with 46,XX congenital adrenal hyperplasia, of whom 6 completed social and gender issue questionnaires. All subjects were assigned male gender at birth, were diagnosed with virilizing congenital adrenal hyperplasia at age greater than 3 years and indicated a male gender identity with sexual orientation to females. Ten of the 12 subjects had always lived as male and 2 who were reassigned to female gender in childhood subsequently self-reassigned as male. Nine of the 12 men had long-term female partners, including 7 married 12 years or more. The 3 subjects without a long-term female partner included 1 priest, 1 who was reassigned female gender, married, divorced and self-reassigned as male, and 1 with a girlfriend and sexual activity. All except the priest and the subject who was previously married when female indicated a strong libido and frequent orgasmic sexual activity. Responses to self-esteem, masculinity, body image, social adjustment and symptom questionnaires suggested adjustments related to the extent of familial and social support. Outcome data on severely masculinized 46,XX patients with congenital adrenal hyperplasia who were assigned male gender at birth indicate male gender identity in adulthood with satisfactory male sexual function in those retaining male genitalia. In men who completed questionnaires results were poorer in those lacking familial/social support. Male gender of rearing may be a viable option for parents whose children are born with congenital adrenal hyperplasia, a 46,XX karyotype and male genitalia, although positive parental and other support, and counseling are needed for adjustment. Copyright © 2010 American Urological Association Education and Research

  14. XY sex chromosome complement, compared with XX, in the CNS confers greater neurodegeneration during experimental autoimmune encephalomyelitis.

    PubMed

    Du, Sienmi; Itoh, Noriko; Askarinam, Sahar; Hill, Haley; Arnold, Arthur P; Voskuhl, Rhonda R

    2014-02-18

    Women are more susceptible to multiple sclerosis (MS) and have more robust immune responses than men. However, men with MS tend to demonstrate a more progressive disease course than women, suggesting a disconnect between the severity of an immune attack and the CNS response to a given immune attack. We have previously shown in an MS model, experimental autoimmune encephalomyelitis, that autoantigen-sensitized XX lymph node cells, compared with XY, are more encephalitogenic. These studies demonstrated an effect of sex chromosomes in the induction of immune responses, but did not address a potential role of sex chromosomes in the CNS response to immune-mediated injury. Here, we examined this possibility using XX versus XY bone marrow chimeras reconstituted with a common immune system of one sex chromosomal type. We found that experimental autoimmune encephalomyelitis mice with an XY sex chromosome complement in the CNS, compared with XX, demonstrated greater clinical disease severity with more neuropathology in the spinal cord, cerebellum, and cerebral cortex. A candidate gene on the X chromosome, toll-like receptor 7, was then examined. Toll-like receptor 7 expression in cortical neurons was higher in mice with XY compared with mice with XX CNS, consistent with the known neurodegenerative role for toll-like receptor 7 in neurons. These results suggest that sex chromosome effects on neurodegeneration in the CNS run counter to effects on immune responses, and may bear relevance to the clinical enigma of greater MS susceptibility in women but faster disability progression in men. This is a demonstration of a direct effect of sex chromosome complement on neurodegeneration in a neurological disease.

  15. Molecular cytogenetic characterization of Rumex papillaris, a dioecious plant with an XX/XY(1)Y (2) sex chromosome system.

    PubMed

    Navajas-Pérez, Rafael; Schwarzacher, Trude; Rejón, Manuel Ruiz; Garrido-Ramos, Manuel A

    2009-01-01

    Rumex papillaris Boiss, & Reut., an Iberian endemic, belongs to the section Acetosa of the genus Rumex whose main representative is R. acetosa L., a species intensively studied in relation to sex-chromosome evolution. Here, we characterize cytogenetically the chromosomal complement of R. papillaris in an effort to enhance future comparative genomic approaches and to better our understanding of sex chromosome structure in plants. Rumex papillaris, as is common in this group, is a dioecious species characterized by the presence of a multiple sex chromosome system (with females 2n = 12 + XX and males 2n = 12 + XY(1)Y(2)). Except for the X chromosome both Y chromosomes are the longest in the karyotype and appear heterochromatic due to the accumulation of at least two satellite DNA families, RAE180 and RAYSI. Each chromosome of pair VI has an additional major heterochromatin block at the distal region of the short arm. These supernumerary heterochromatic blocks are occupied by RAE730 satellite DNA family. The Y-related RAE180 family is also present in an additional minor autosomal locus. Our comparative study of the chromosomal organization of the different satellite-DNA sequences in XX/XY and XX/XY(1)Y(2) Rumex species demonstrates that of active mechanisms of heterochromatin amplification occurred and were accompanied by chromosomal rearrangements giving rise to the multiple XX/XY(1)Y(2) chromosome systems observed in Rumex. Additionally, Y(1) and Y(2) chromosomes have undergone further rearrangements leading to differential patterns of Y-heterochromatin distribution between Rumex species with multiple sex chromosome systems.

  16. Terminal deletion of the long arm of chromosome 3 [46,XX,del(3)(q27{r_arrow}qter)

    SciTech Connect

    Chitayat, D.; Babul, R.; Silver, M.M.

    1996-01-02

    We report on a terminal deletion of the long arm of chromosome 3[46,XX,del(3)(q27{r_arrow}qter)] in a female newborn infant who died 45 hours after delivery and had multiple congenital abnormalities including bilateral anophthalmia, congenital heart disease, and abnormal genitalia. The findings are compared to those of four previously reported cases with terminal de (3q). 8 refs., 4 figs., 1 tab.

  17. XX/XY System of Sex Determination in the Geophilomorph Centipede Strigamia maritima.

    PubMed

    Green, Jack E; Dalíková, Martina; Sahara, Ken; Marec, František; Akam, Michael

    2016-01-01

    We show that the geophilomorph centipede Strigamia maritima possesses an XX/XY system of sex chromosomes, with males being the heterogametic sex. This is, to our knowledge, the first report of sex chromosomes in any geophilomorph centipede. Using the recently assembled Strigamia genome sequence, we identified a set of scaffolds differentially represented in male and female DNA sequence. Using quantitative real-time PCR, we confirmed that three candidate X chromosome-derived scaffolds are present at approximately twice the copy number in females as in males. Furthermore, we confirmed that six candidate Y chromosome-derived scaffolds contain male-specific sequences. Finally, using this molecular information, we designed an X chromosome-specific DNA probe and performed fluorescent in situ hybridization against mitotic and meiotic chromosome spreads to identify the Strigamia XY sex-chromosome pair cytologically. We found that the X and Y chromosomes are recognizably different in size during the early pachytene stage of meiosis, and exhibit incomplete and delayed pairing.

  18. Post-stall wind tunnel data for NACA 44XX series airfoil sections

    SciTech Connect

    Ostowari, C.; Naik, D.

    1985-01-01

    Wind turbine blades operate over a wide angle of attach range. Unlike aircraft, a wind turbine's angle of attach range extends deep into stall where the three-dimensional performance characteristics of airfoils are not generally known. Peak power predictions upon which wind turbine components are sized depend on a good understanding of a blade's post-stall characteristics. The purpose of this wind tunnel study is to characterize the performance characteristics of a blade in stall as a function of its aspect ratio, airfoil thickness, and Reynolds number. This report documents results of the wind tunnel investigation of constant chord blades having four aspect ratios, with NACA 44XX series airfoil sections, at angles of attack ranging from -10/sup 0/ to 110/sup 0/. Tests were conducted at Reynolds number ranging from 0.25 x 106 to 1.0 x 106. The thickness ratios studied were 0.18, 0.15, and 0.12, and 0.09. The aspect ratios were 6, 9, 12 and infinity. Results of force and pitching moment measurements over the angle of attack range for all combinations of Reynolds numbers, thickness, and aspect ratios, and the effects of boundary layer tripping are presented.

  19. Diagnostics of SHOX gene rearrangement in 46,XX women with idiopathic short stature.

    PubMed

    Mitka, Magdalena; Bednarek, Michał; Kałużewski, Bogdan

    2016-01-01

    The SHOX gene has been mapped at the pseudoautosomal region 1 (PAR1) of chromosomes X (Xp22.33) and Y (Yp11.32). The loss of SHOX gene functionality is assumed to be responsible for the Leri-Weill syndrome formation and the disproportionate short stature (DSS). The SHOX gene rearrangements constitute the majority of cases of gene functionality loss. Therefore, a practical application of the method, which allows for the diagnostics of the gene rearrangements, becomes a primary issue. With such an assumption, the MLPA technique (multiplex ligation - dependent probe amplification) becomes the method of choice. DNA samples were evaluated in the study by means of the MLPA method. The DNA was isolated from peripheral blood of sixty-three (63) 46,XX patients with short stature. Out of the examined patients, deletions within the SHOX gene were found in five (5) patients, and duplication at the PAR1 regulatory region of the SHOX gene in one (1) case. The obtained results confirm the opinion that the MLPA method, while enabling the diagnostics of the etiopathogenetic factor of short stature, identified in approximately 9.5% of cases, is a useful tool in the diagnostics of SHOX gene deletion and duplication. (Endokrynol Pol 2016; 67 (4): 397-402).

  20. [THE IMPROVEMENT OF CITIES AND SANITARY CONTROL IN RUSSIA IN LATE XIX--EARLY XX CENTURIES].

    PubMed

    Sherstneva, E V

    2015-01-01

    The article considers activity of municipal self-governments of Russia concerning support of sanitary epidemiological well-being of cities in the late XIX--early XX centuries. The acuteness of problem of sanitary conditions of urban settlements particularly became visible in post-reform period due to increasing of number of urban population, alteration of setup and rhythm of life in cities, appearance of new forms of worker's daily chores. Al this, against the background of underdevelopment of communal sphere aggravated epidemiological situation in cities. The impulse to improvement and development of sanitary control was made by the city regulations of 1870 presenting to town authorities the right to deal with sanitary issues. The significant input into improvement of cities was made first of all at the expense of construction of water supplies and sewerage and support of sanitary control of these spheres of municipal economy. Under town councils of many cities the sanitary commissions were organized to support permanent sanitary control in town. The development of town sanitation followed the way of specialization. The housing and communal, trade and food, school and sanitary and sanitary and veterinary control were organized.

  1. XX/XY System of Sex Determination in the Geophilomorph Centipede Strigamia maritima

    PubMed Central

    Green, Jack E.; Dalíková, Martina; Sahara, Ken; Marec, František; Akam, Michael

    2016-01-01

    We show that the geophilomorph centipede Strigamia maritima possesses an XX/XY system of sex chromosomes, with males being the heterogametic sex. This is, to our knowledge, the first report of sex chromosomes in any geophilomorph centipede. Using the recently assembled Strigamia genome sequence, we identified a set of scaffolds differentially represented in male and female DNA sequence. Using quantitative real-time PCR, we confirmed that three candidate X chromosome-derived scaffolds are present at approximately twice the copy number in females as in males. Furthermore, we confirmed that six candidate Y chromosome-derived scaffolds contain male-specific sequences. Finally, using this molecular information, we designed an X chromosome-specific DNA probe and performed fluorescent in situ hybridization against mitotic and meiotic chromosome spreads to identify the Strigamia XY sex-chromosome pair cytologically. We found that the X and Y chromosomes are recognizably different in size during the early pachytene stage of meiosis, and exhibit incomplete and delayed pairing. PMID:26919730

  2. Radiative L-Shell Transitions in Fe XIX and Fe XX Ions

    NASA Astrophysics Data System (ADS)

    Kotochigova, S.; Linnik, M.; Kirby, K. P.; Brickhouse, N. S.

    2010-01-01

    We compute the wavelengths and oscillator strengths for the 3s, 3d → 2p, and 3p → 2s emission lines in Fe XIX and Fe XX ions by using a configuration interaction Dirac-Fock and Dirac-Fock-Sturm method combined with second-order Brillouin-Wigner perturbation theory. We provide a complete list of computed wavelengths and oscillator strengths in both the velocity and length gauge for these transitions, many of which have never previously been reported. A comparison of our data with laboratory measurements and other theoretical predictions allows us to estimate an uncertainty of ~2 mÅ in the wavelengths and an uncertainty of 2%-3% in the oscillator strengths. We expect that our calculations will provide a means of identifying emission lines from astrophysical sources and improve the ability to detect blending in X-ray grating spectra from Chandra and XMM-Newton. As an example, we present a simulated emission spectrum of Capella and find improved agreement between the observations and our calculations, compared with previous data sets.

  3. RADIATIVE L-SHELL TRANSITIONS IN Fe XIX AND Fe XX IONS

    SciTech Connect

    Kotochigova, S.; Linnik, M.; Kirby, K. P.; Brickhouse, N. S.

    2010-01-01

    We compute the wavelengths and oscillator strengths for the 3s, 3d {yields} 2p, and 3p {yields} 2s emission lines in Fe XIX and Fe XX ions by using a configuration interaction Dirac-Fock and Dirac-Fock-Sturm method combined with second-order Brillouin-Wigner perturbation theory. We provide a complete list of computed wavelengths and oscillator strengths in both the velocity and length gauge for these transitions, many of which have never previously been reported. A comparison of our data with laboratory measurements and other theoretical predictions allows us to estimate an uncertainty of {approx}2 mA in the wavelengths and an uncertainty of 2%-3% in the oscillator strengths. We expect that our calculations will provide a means of identifying emission lines from astrophysical sources and improve the ability to detect blending in X-ray grating spectra from Chandra and XMM-Newton. As an example, we present a simulated emission spectrum of Capella and find improved agreement between the observations and our calculations, compared with previous data sets.

  4. Mutation of foxl2 or cyp19a1a Results in Female to Male Sex Reversal in XX Nile Tilapia.

    PubMed

    Zhang, Xianbo; Li, Mengru; Ma, He; Liu, Xingyong; Shi, Hongjuan; Li, Minghui; Wang, Deshou

    2017-08-01

    It is well accepted that Forkhead box protein L2 (Foxl2) and aromatase (Cyp19a1; the enzyme responsible for estrogen synthesis) are critical for ovarian development in vertebrates. Knockouts of Foxl2 and Cyp19a1 in goat, mouse, and zebrafish have revealed similar but not identical functions across species. Functional analyses of these two genes in other animals are needed to elucidate their conserved roles in vertebrate sexual development. In this study, we established foxl2 and cyp19a1a mutant lines in Nile tilapia. Both foxl2-/- and cyp19a1a-/- XX fish displayed female-to-male sex reversal. Sf1, Dmrt1, and Gsdf were upregulated in the foxl2-/- and the cyp19a1a-/- XX gonads. Downregulation of Cyp19a1a and serum estradiol-17β level, and upregulation of Cyp11b2 and serum 11-ketotestosterone level were observed in foxl2-/- XX fish. The mutant phenotype of foxl2-/- XX individuals could be rescued by 17β-estradiol treatment from 5 to 30 days after hatching (dah). Upregulation of Star1, the enzyme involved in androgen production in tilapia, was also observed in the foxl2-/- XX gonad at 30 and 90 dah. In vitro promoter analyses consistently demonstrated that Foxl2 could suppress the transcription of star1 in a dose-dependent manner. In addition, compared with the control XX gonad, fewer germ cells were detected in the foxl2-/- XX, cyp19a1a-/- XX, and control XY gonads 10 dah. These results demonstrate that Foxl2 promotes ovarian development by upregulating Cyp19a1a expression and repressing male pathway gene expression. These results extend the study of Foxl2 and Cyp19a1a loss of function to a commercially important fish species. Copyright © 2017 Endocrine Society.

  5. Sex steroid levels in XY males and sex-reversed XX males, of rainbow trout (Oncorhynchus mykiss), during the reproductive cycle.

    PubMed

    Espinosa, E; Josa, A; Gil, L; González, N

    2011-02-01

    In this study, the annual cycle of the gonadal steroids testosterone (T), 11-ketotestosterone (11-KT), 17β-oestradiol (E2) and 17α, 20β-dihydroxy-4-pregnen-3-one (DHP) was determined using radioimmunoassay and then compared, for XY males (n=35) and sex-reversed XX males (n=27) rainbow trout, to establish possible endocrinology differences. Both in XY males and sex-reversed XX males, significant correlation was shown between body weight and T (r=0.5046 and 0.34078, respectively; p<0.0001) or KT (r=0.52494 and 0.43545, respectively; p<0.0001) concentrations. Plasma androgen levels in XY and sex-reversed XX males were similar and showed an intense seasonal variation. The highest levels for T and 11-KT were detected from December to April with a peak in January (51.67 ± 5.11 and 61.95 ± 4.25 ng/ml, for XY males and 57.1 ± 5.82 and 59.27 ± 4.84 ng/ml, respectively, for XX males). In addition, there was a positive correlation (p<0.0001) between T and 11-KT levels for XY males (r=0.7533) and sex-reversed XX males (r=0.6019). Concentrations of DHP in XY males also showed seasonal variation with a peak in February (25.18 ± 12.99 ng/ml). However, DHP levels in sex-reversed XX males were undetectable (<0.1 ng/ml) over the year. Levels of E2 were undetectable through the year in both groups of trout. In conclusion, the androgenic and oestrogenic profiles of sex-reversed XX males were similar to those observed in XY males. The only difference in the annual gonadal steroid cycle between XY and sex-reversed XX males was in the DHP profile.

  6. Unique sex chromosome systems in Ellobius: How do male XX chromosomes recombine and undergo pachytene chromatin inactivation?

    PubMed

    Matveevsky, Sergey; Bakloushinskaya, Irina; Kolomiets, Oxana

    2016-07-18

    Most mammalian species have heteromorphic sex chromosomes in males, except for a few enigmatic groups such as the mole voles Ellobius, which do not have the Y chromosome and Sry gene. The Ellobius (XX ♀♂) system of sex chromosomes has no analogues among other animals. The structure and meiotic behaviour of the two X chromosomes were investigated for males of the sibling species Ellobius talpinus and Ellobius tancrei. Their sex chromosomes, despite their identical G-structure, demonstrate short synaptic fragments and crossover-associated MLH1 foci in both telomeric regions only. The chromatin undergoes modifications in the meiotic sex chromosomes. SUMO-1 marks a small nucleolus-like body of the meiotic XX. ATR and ubiH2A are localized in the asynaptic area and the histone γH2AFX covers the entire XX bivalent. The distribution of some markers of chromatin inactivation differentiates sex chromosomes of mole voles from those of other mammals. Sex chromosomes of both studied species have identical recombination and meiotic inactivation patterns. In Ellobius, similar chromosome morphology masks the functional heteromorphism of the male sex chromosomes, which can be seen at meiosis.

  7. Unique sex chromosome systems in Ellobius: How do male XX chromosomes recombine and undergo pachytene chromatin inactivation?

    PubMed Central

    Matveevsky, Sergey; Bakloushinskaya, Irina; Kolomiets, Oxana

    2016-01-01

    Most mammalian species have heteromorphic sex chromosomes in males, except for a few enigmatic groups such as the mole voles Ellobius, which do not have the Y chromosome and Sry gene. The Ellobius (XX ♀♂) system of sex chromosomes has no analogues among other animals. The structure and meiotic behaviour of the two X chromosomes were investigated for males of the sibling species Ellobius talpinus and Ellobius tancrei. Their sex chromosomes, despite their identical G-structure, demonstrate short synaptic fragments and crossover-associated MLH1 foci in both telomeric regions only. The chromatin undergoes modifications in the meiotic sex chromosomes. SUMO-1 marks a small nucleolus-like body of the meiotic XX. ATR and ubiH2A are localized in the asynaptic area and the histone γH2AFX covers the entire XX bivalent. The distribution of some markers of chromatin inactivation differentiates sex chromosomes of mole voles from those of other mammals. Sex chromosomes of both studied species have identical recombination and meiotic inactivation patterns. In Ellobius, similar chromosome morphology masks the functional heteromorphism of the male sex chromosomes, which can be seen at meiosis. PMID:27425629

  8. The Sertoli Cell Only Syndrome and Glaucoma in a Sex – Determining Region Y (SRY) Positive XX Infertile Male

    PubMed Central

    Jain, Manish; V, Veeramohan; Chaudhary, Isha; Halder, Ashutosh

    2013-01-01

    The XX male syndrome is a rare genetic disorder. The phenotype is variable; it ranges from a severe impairment of the external genitalia to a normal male phenotype with infertility. It generally results from an unequal crossing over between the short arms of the sex chromosomes (X and Y). We are reporting a case of a 38-year-old man who presented with infertility and the features of hypogonadism and glaucoma. The examinations revealed normal external male genitalia, soft small testes, gynaecomastia and glaucoma. The semen analysis showed azoospermia. The serum gonadotropins were high, with low Anti Mullerian Hormone (AMH) and Inhibin B levels. The chromosomal analysis demonstrated a 46, XX karyotype. Fluorescent In-Situ Hybridization (FISH) and Polymerase Chain Reaction (PCR) revealed the presence of a Sex-determining Region Y (SRY). Testicular Fine Needle Aspiration Cytology (FNAC) revealed the Sertoli Cell Only Syndrome (SCOS). The presence of only Sertoli Cells in the testes, with glaucoma in the XX male syndrome, to our knowledge, has not been reported in the literature. PMID:23998093

  9. Wide spectrum of NR5A1‐related phenotypes in 46,XY and 46,XX individuals

    PubMed Central

    Domenice, Sorahia; Machado, Aline Zamboni; Ferreira, Frederico Moraes; Ferraz‐de‐Souza, Bruno; Lerario, Antonio Marcondes; Lin, Lin; Nishi, Mirian Yumie; Gomes, Nathalia Lisboa; da Silva, Thatiana Evelin; Silva, Rosana Barbosa; Correa, Rafaela Vieira; Montenegro, Luciana Ribeiro; Narciso, Amanda; Costa, Elaine Maria Frade; Achermann, John C

    2016-01-01

    Steroidogenic factor 1 (NR5A1, SF‐1, Ad4BP) is a transcriptional regulator of genes involved in adrenal and gonadal development and function. Mutations in NR5A1 have been among the most frequently identified genetic causes of gonadal development disorders and are associated with a wide phenotypic spectrum. In 46,XY individuals, NR5A1‐related phenotypes may range from disorders of sex development (DSD) to oligo/azoospermia, and in 46,XX individuals, from 46,XX ovotesticular and testicular DSD to primary ovarian insufficiency (POI). The most common 46,XY phenotype is atypical or female external genitalia with clitoromegaly, palpable gonads, and absence of Müllerian derivatives. Notably, an undervirilized external genitalia is frequently seen at birth, while spontaneous virilization may occur later, at puberty. In 46,XX individuals, NR5A1 mutations are a rare genetic cause of POI, manifesting as primary or secondary amenorrhea, infertility, hypoestrogenism, and elevated gonadotropin levels. Mothers and sisters of 46,XY DSD patients carrying heterozygous NR5A1 mutations may develop POI, and therefore require appropriate counseling. Moreover, the recurrent heterozygous p.Arg92Trp NR5A1 mutation is associated with variable degrees of testis development in 46,XX patients. A clear genotype‐phenotype correlation is not seen in patients bearing NR5A1 mutations, suggesting that genetic modifiers, such as pathogenic variants in other testis/ovarian‐determining genes, may contribute to the phenotypic expression. Here, we review the published literature on NR5A1‐related disease, and discuss our findings at a single tertiary center in Brazil, including ten novel NR5A1 mutations identified in 46,XY DSD patients. The ever‐expanding phenotypic range associated with NR5A1 variants in XY and XX individuals confirms its pivotal role in reproductive biology, and should alert clinicians to the possibility of NR5A1 defects in a variety of phenotypes presenting with gonadal

  10. Torino 2006. XX Olympic and IX Paralympic Winter Games: the ENT experience

    PubMed Central

    Succo, G; Crosetti, E; Mattiazzo, A; Riontino, E; Massazza, G

    2008-01-01

    Summary A total of 27 competition days, more than 3000 athletes, over 10,000 components of the Olympic family, 3,500 workers, 2,500 volunteers, an overall business of more than 2 billion Euros. These, in a nutshell, are just a few of the data concerning the XX Olympic and the IX Paralympic Winter Games, Torino, Italy, 2006. Such a huge event, obviously required a meticulously organized medical service to cope with the healthcare of the athletes, official workers and the Olympic family, distributed over a geographic area of approximately 80 km in diameter. An ENT service was organized within the medical service, which was divided between 3 Polyclinics, in which 12 ENT Specialists were on duty. The present report gives an account of the final data concerning the service involved, together with a description of the approach used in the actual organization, with a view to providing useful information for colleagues who will be called upon, for a similar service, in future Olympic Winter Games. The ENT healthcare offered was confirmed to be proportional to the requirements, both from a qualitative and quantitative point of view. All the ENT specialists involved, reported having gained an immense store of human experience from having lived the Olympic atmosphere as a volunteer exerting one’s own profession. The facilities available in the Polyclinics, which were at a considerable distance from the Hospital, were found to be more than adequate with respect to the pathological conditions and service requested, particularly in 17% of the cases which would otherwise have been sent to a Hospital Outpatient Unit at least 80 km away. PMID:18646571

  11. Hurst exponent of very long birth time series in XX century Romania. Social and religious aspects

    NASA Astrophysics Data System (ADS)

    Rotundo, G.; Ausloos, M.; Herteliu, C.; Ileanu, B.

    2015-07-01

    The Hurst exponent of very long birth time series in Romania has been extracted from official daily records, i.e. over 97 years between 1905 and 2001 included. The series result from distinguishing between families located in urban (U) or rural (R) areas, and belonging (Ox) or not (NOx) to the orthodox religion. Four time series combining both criteria, (U,R) and (Ox, NOx), are also examined. A statistical information is given on these sub-populations measuring their XX-th century state as a snapshot. However, the main goal is to investigate whether the "daily" production of babies is purely noisy or is fluctuating according to some non trivial fractional Brownian motion, - in the four types of populations, characterized by either their habitat or their religious attitude, yet living within the same political regime. One of the goals was also to find whether combined criteria implied a different behavior. Moreover, we wish to observe whether some seasonal periodicity exists. The detrended fluctuation analysis technique is used for finding the fractal correlation dimension of such (9) signals. It has been first necessary, due to two periodic tendencies, to define the range regime in which the Hurst exponent is meaningfully defined. It results that the birth of babies in all cases is a very strongly persistent signal. It is found that the signal fractal correlation dimension is weaker (i) for NOx than for Ox, and (ii) or U with respect to R. Moreover, it is observed that the combination of U or R with NOx or OX enhances the UNOx, UOx, and ROx fluctuations, but smoothens the RNOx signal, thereby suggesting a stronger conditioning on religiosity rituals or rules.

  12. Climate Change of Franz Josef Land in the XX-XXI Centuries

    NASA Astrophysics Data System (ADS)

    Shilovtseva, Olga; Romanenko, Fedor

    2016-04-01

    The results of climatic observations on the most northern land of Eurasia - Franz Josef Land, that was discovered in 1874, are presented. The gaps in the observations of the observatory named after Ernst Krenkel (Hayes's Island) were supplemented by calculations using reanalysis ERA Interim. It was received the positive trend in surface air temperature during 1958-2013. It is mainly achieved by increasing of the air temperature in winter but the summer trend is not statistically significant. Data of observation and reanalysis are perfectly correlated in cold period when underlying surface is uniform (correlation coefficient of more than 0.95). In summer, the correlation coefficients between the calculated and the real data are significantly lower (up to 0.68). This fact may be a consequence of the small values of the mean air temperatures of summer months (for example, during the July they varied in the interval -1-+2 degrees C.). Furthermore, it may be caused by the difficulty of model reproduction of the real state of the underlying surface, where land, ice, snow and water are chaotically combined. The analysis of circulation types by B.L. Dzerdzeevsky has shown that in the mid-XX Century, the northern meridional and western zonal types of circulation were replaced by southern meridional one, which prevailed during the first decade of the XXI too. This causes a reduction of the ice cover period, which resulted in a strengthening of the beach erosion and of slope processes. But short-term flows of warm air from the south, causing a catastrophic melting of glaciers, were also repeatedly marked in the past. This work is supported by the Russian Science Foundation (project № 14-37-00038) and by the national park "Russian Arctic".

  13. Reliability of high performance 9xx-nm single emitter laser diodes

    NASA Astrophysics Data System (ADS)

    Bao, Ling; Wang, Jun; Devito, Mark; Xu, Dapeng; Wise, Damian; Leisher, Paul; Grimshaw, Mike; Dong, Weimin; Zhang, Shiguo; Price, Kirk; Li, Daming; Bai, Chendong; Patterson, Steve; Martinsen, Rob

    2010-02-01

    This paper presents reliable high power and high brightness 9xx-nm single emitter laser diodes, which have been designed for various multi-emitter fiber-coupled modules. Diode lasers from legend generation have been life-tested with currents up to 14A at heat-sink and junction temperatures of 50°C and 80°C respectively, and have accumulated more than 15,000 hours of life-test duration. In order to further improve reliable operational power and optimize beam quality, new generation devices have been developed. The new devices demonstrated more than 20W CW rollover power without catastrophic optical mirror damage (COMD). Near-field/far-field patterns have also been improved significantly. In addition to step-stress life-tests, a 7-level multi-cell life-test was designed to investigate acceleration factors relative to the operation conditions. Junction temperatures ranging from 60°C to 110°C and current from 14A to 18A were used in this multi-cell life-test. The ongoing multi-cell life-test has accumulated 1.3 million raw device hours and shown very few device failures in up to 7000 hours duration. Such a low failure rate doesn't allow a meaningful estimation of acceleration factors. When nominal acceleration factors are used, multi-cell life-test data supports ~500 FIT, with 90% confidence, at 10W, 33°C/50°C heat-sink/junction temperatures.

  14. High power laser diodes at 14xx nm wavelength range for industrial and medical applications

    NASA Astrophysics Data System (ADS)

    Telkkälä, Jarkko; Boucart, Julien; Krejci, Martin; Crum, Trevor; Lichtenstein, Norbert

    2014-03-01

    We report on the development of the latest generation of high power laser diodes at 14xx nm wavelength range suitable for industrial applications such as plastics welding and medical applications including acne treatment, skin rejuvenation and surgery. The paper presents the newest chip generation developed at II-VI Laser Enterprise, increasing the output power and the power conversion efficiency while retaining the reliability of the initial design. At an emission wavelength around 1440 nm we applied the improved design to a variety of assemblies exhibiting maximum power values as high as 7 W for broad-area single emitters. For 1 cm wide bars on conductive coolers and for bars on active micro channel coolers we have obtained 50 W and 72 W in continuous wave (cw) operation respectively. The maximum power measured for a 1 cm bar operated with 50 μs pulse width and 0.01% duty cycle was 184 W, demonstrating the potential of the chip design for optimized cooling. Power conversion efficiency values as high as 50% for a single emitter device and over 40% for mounted bars have been demonstrated, reducing the required power budget to operate the devices. Both active and conductive bar assembly configurations show polarization purity greater than 98%. Life testing has been conducted at 95 A, 50% duty cycle and 0.5 Hz hard pulsed operation for bars which were soldered to conductive copper CS mounts using our hard solder technology. The results after 5500 h, or 10 million "on-off" cycles show stable operation.

  15. Male genitoplasty for 46 XX congenital adrenal hyperplasia patients presenting late and reared as males

    PubMed Central

    Sharma, Shilpa; Gupta, Devendra K.

    2012-01-01

    Aim: To evaluate the clinical profile and management of 46 XX Congenital Adrenal Hyperplasia (CAH) patients presenting with severe virilization and assigned a male gender. Materials and Methods: Of 173 children diagnosed with CAH at the Pediatric Intersex Clinic since 1980, seven children with CAH presented late with severe virilization and were reared as males. All of them were assigned the male sex with removal of the female adnexa. Six were treated with male genitoplasty. Appropriate hormonal supplementation was offered after puberty. Results: The mean age at presentation was 14.2 years (7 – 21). Six patients had presented after puberty, only one at seven years of age. Staged male genitoplasty comprising of chordee correction, male urethroplasty, and bilateral testicular prosthesis was performed. The female adnexa (uterus, ovaries, most of the upper vagina, and the fallopian tubes) were removed. The mental makeup was masculine in six and bigender in one. Bilateral mastectomy was performed at puberty in all. Hormonal treatment comprised of glucocorticoids and testosterone. Six patients were comfortable with the outcome of the masculinizing genitoplasty. One had a short-sized phallus. One had repeated attacks of urinary tract infection arising from the retained lower vaginal pouch. Social adjustments were good in all, except in one who had a bigender mental makeup. Conclusion: CAH patients with severe virilization presenting late and reared as males are extremely rare. However, the assigned gender can be retained adequately as males, meeting the socioeconomic compulsions of the society. The results are satisfactory following appropriate surgical procedures and hormonal supplementation. PMID:23226638

  16. Norditropin SimpleXx: a liquid human growth hormone formulation, a pen system and an auto-insertion device.

    PubMed

    Müller, J; Skakkebaek, N E; Jacobsen, B B; Keller, E; Heinrich, U; Hartmann, K; Hokken-Koelega, A C; Delemarre van de Waal, H A

    1999-01-01

    Patient compliance is of vital importance for the outcome of any medical therapy. Compliance is especially a problem in long-term treatment of non-life threatening diseases, such as growth retardation in children. Until recently, all human growth hormone (hGH) products required a reconstitution process. Norditropin((R)) SimpleXx(TM) is a liquid formulation of the biosynthetic hGH product Norditropin((R)), and, together with an improved NovoPen((R)) 1.5, NordiPen(TM), and an auto-insertion device, PenMate(TM)/NordiPenMate(TM), it has been developed in order to ease the injection process for patients. A randomized, open, multicentre, crossover trial compared Norditropin((R)) SimpleXx(TM)/improved NovoPen((R)) 1.5 with freeze-dried Norditropin((R)) PenSet((R))/Nordiject((R)). A total of 67 children with GH deficiency, aged 5-18 years, were treated with either Norditropin((R)) SimpleXx(TM) for 6 weeks followed by Norditropin((R)) for 6 weeks or the opposite (sequences I and II, respectively). Acceptability/convenience and pain perception were evaluated by questionnaire after each period. The function and handling of the PenMate(TM) were evaluated in a Dutch trial by 27 GH-treated children with intrauterine growth retardation, aged 4-16 years, and their parents. All children were accustomed to using the Nordiject((R)) pen. The evaluation of the PenMate(TM) was based on a questionnaire. A similar trial was conducted in England, in which the NordiPen(TM) and the NordiPenMate(TM) were evaluated by 25 GH-treated children and their parents. Norditropin((R)) SimpleXx(TM) was found to be easier to inject by 64% of the children, and 98% of the children found the system easier to use overall. There was no difference in pain perception between the two administration systems, as judged by questionnaires and visual analogue scale score. Three out of four patients preferred to continue treatment with Norditropin((R)) SimpleXx(TM). The safety profiles of the two systems were similar

  17. The role of the sex-determining region Y gene in the etiology of 46,XX maleness

    SciTech Connect

    Fechner, P.Y.; Marcantonio, S.M.; Jaswaney, V.; Stetten, G.; Migeon, C.J.; Smith, K.D.; Berkovitz, G.D. ); Goodfellow, P.N. ); Amrhein, J.A. ); Bard, P.A. ); Lee, P.A. ); Reid, C. ); Tsalikian, E. ); Urban, M.D. )

    1993-03-01

    The condition of 46,XX maleness is characterized by testicular development in subjects who have two X chromosomes but who lack a normal Y chromosome. Several etiologies have been proposed to explain 46,XX maleness: (1) translocation of the testis-determining factor from the Y to the X chromosome, (2) mutation in an autosomal or X chromosome gene which permits testicular determination in the absence of TDF, and (3) undetected mosaicism with a Y-bearing cell line. The authors evaluated 10 affected subjects who were ascertained for different reasons and who had several distinct phenotypes. Six subjects had inherited sequences from the short arm of the Y chromosome including the sex-determining region Y gene (SRY). Five of the subjects were pubertal at the time of evaluation and had a phenotype similar to that of Klinefelter syndrome with evidence of Sertoli cell and Leydig cell dysfunction. One subject had evidence from Southern blot analysis and in situ hybridization for the presence of an intact Y chromosome in approximately 1% of cells. Three subjects lacked Y sequences by Southern blot analysis and by polymerase chain reaction amplification of SRY. These subjects were ascertained in the newborn period because of congenital anomalies. One had multiple anomalies including cardiac abnormalities; one had cardiac anomalies alone; and one had ambiguous genitalia. The data confirm the genetic heterogeneity of 46,XX maleness, in which some subjects have SRY while other subjects lack it. In addition, there is phenotypic heterogeneity among subjects who lack SRY suggesting that there is also genetic heterogeneity within this subgroup. 43 refs., 3 figs., 4 tabs.

  18. Molecular and cytogenetic studies in a case of XX SRY-negative sex reversal in an Arabian horse.

    PubMed

    Ciotola, F; Albarella, S; Pasolini, M P; Auletta, L; Esposito, L; Iannuzzi, L; Peretti, V

    2012-01-01

    An 18-month-old Arabian foal characterized by a stallion-like appearance was submitted for cytogenetic and molecular genetics examinations due to abnormalities of external genitalia and the presence of ovotestis-like structures in the abdominal cavity. By RB-banding the animal showed the normal female equine karyotype (2n = 64,XX). Molecular analysis revealed the absence of the SRY and ZFY genes and the presence of ZFX, a typical female equine condition. The entire RSPO1 coding region was examined to exclude its involvement. Although a SNP was found in exon 3, it was not responsible for an amino acid substitution.

  19. The Schrödinger System H=-12(tot)a∂xx+12ω2(tto)bX2

    NASA Astrophysics Data System (ADS)

    Nieto, Michael Martin; Truax, D. Rodney

    2001-08-01

    We attack the specific time-dependent Hamiltonian problem H=-12(tot)a∂xx+12ω2(tto)bx2. This corresponds to a time-dependent mass (TM) Schrödinger equation. We give the specific transformations to a different time-dependent quadratic Schrödinger equation (TQ) and to a different time-dependent oscillator (TO) equation. For each Schrödinger system, we give the Lie algebra of space-time symmetries, the number states, the squeezed-state and (with their classical motion), (Δx)2, (Δp)2, and the uncertainty product.

  20. The Metaphorical Applications of Heavenly Bodies and Phenomena in Western Armenian Poetry at the Beginning of the XX Century

    NASA Astrophysics Data System (ADS)

    Arakelyan, Karine

    2015-07-01

    The metaphorical applications of heavenly bodies and phenomena in Western Armenian poetry at the beginning of the XX century are very diverse and of great variety. Art Workers eulogize the creation of God, admire the beauty of stars, and perceive the man as a part of nature and in the close connection with all other parts. These units are often used for bringing to light one's inner life, his old gone paths, expectations and hopes, many times they become the heart and the basis of poetical image and create unique beauty.

  1. Autoimmune myelofibrosis accompanied by Sjögren's syndrome in a 47, XXX/46, XX mosaic woman.

    PubMed

    Takahashi, Tohru

    2014-01-01

    This report describes a patient with autoimmune myelofibrosis accompanied by Sjögren's syndrome (SS). A 36-year-old woman was admitted due to petechiae, purpura, gingival bleeding, dyspnea on exertion, and a lack of concentration. She had pancytopenia and was diagnosed with SS. A bone marrow study showed hypercellular marrow with reticulin fibrosis. Lymphocytic infiltrates and aggregates composed of a mixture of T and B cells in the marrow were also observed. A chromosomal analysis of the marrow cells showed 47, XXX and an analysis of peripheral lymphocytes revealed 47, XXX/46, XX mosaic results. The patient's cytopenia resolved following treatment with oral prednisolone.

  2. Ullrich-Turner phenotype with unusual manifestation in a patient with mosaicism 45,X/47,XX,+18

    SciTech Connect

    Franceschini, P.; Guala, A.; Camerano, P.; Franceschini, D.; Vardeu, M.P.; Signorile, F.

    1996-03-01

    We report on a girl with Ullrich-Turner phenotype and 45,X/47,XX,+18 chromosomal mosaicism. Only two other patients with similar mosaicism have been reported, both girls with XY sex chromosome constitution. The face of the patient was highly asymmetric, the right side being almost normal, the left showing a typical Ullrich-Turner syndrome appearance. This clinical impression was strengthened by photographic doubling of both hemifaces. The patient had normal intelligence and did not show any stigmata of trisomy 18. 13 refs., 2 figs., 1 tab.

  3. PREFACE: XX International School on Nuclear Physics, Neutron Physics and Applications (Varna2013)

    NASA Astrophysics Data System (ADS)

    Stoyanov, Chavdar; Dimitrova, Sevdalina

    2014-09-01

    The present volume contains the lectures and short talks given at the XX International School on Nuclear Physics, Neutron Physics and Applications. The School was held from 16-22 September 2013 in 'Club Hotel Bolero' located in 'Golden Sands' (Zlatni Pyasaci) Resort Complex on the Black Sea coast, near Varna, Bulgaria. The School was organized by the Institute for Nuclear Research and Nuclear Energy of Bulgarian Academy of Sciences. Co-organizer of the School was the Bulgarian Nuclear Regulatory Agency and the Bogoliubov Laboratory of Theoretical Physics of Joint Institute for Nuclear Research - Dubna. Financial support was also provided by the Bulgarian Ministry of Education and Science. According to the long-standing tradition the School has been held every second year since 1973. The School's program has been restructured according to our enlarged new international links and today it is more similar to an international conference than to a classical nuclear physics school. This new image attracts many young scientists and students from around the world. This year, 2013, we had the pleasure to welcome more than sixty distinguished scientists as lecturers. Additionally, twenty young colleagues received the opportunity to present a short contribution. Ninety-four participants altogether enjoyed the scientific presentations and discussions as well as the relaxing atmosphere at the beach and during the pleasant evenings. The program of the School ranged from latest results in fundamental areas such as nuclear structure and reactions to the hot issues of application of nuclear methods, reactor physics and nuclear safety. The main topics have been the following: Nuclear excitations at various energies. Nuclei at high angular moments and temperature. Structure and reactions far from stability. Symmetries and collective phenomena. Methods for lifetime measurements. Astrophysical aspects of nuclear structure. Neutron nuclear physics. Nuclear data. Advanced methods in

  4. Spanish Radiology in the second half of the XX Century: a view from inside.

    PubMed

    Bonmatí, José

    2008-09-01

    Radiology was born in 1896 with the immediate recognition of the diagnostic value of X-rays in medicine and progressed throughout the XX Century with the increasing knowledge of its properties and clinical applications. By mid-century Radiology was a respected clinical specialty in advanced countries, the radiological report was a requirement in hospital practice and radiologists' opinions requested in scientific meetings. In the last decades of the century has had a spectacular expansion with the emergence of new imaging modalities and revolutionary technologies that have transformed the specialty worldwide. In Spain Radiology lagged behind needs and demand in 1950. Radiological practice was unregulated and performance of X-ray exams by non-radiologists was common. Teaching of Radiology was non-existent in Medical Schools or postgraduation. The diagnostic value of the specialty was unrecognized by physicians and the role of radiologists ignored. Most hospital radiology services were poorly equipped and functionally inadequate. The shadow of the Civil War (1936-39) was conditioning Radiology in the country. The point of inflexion in the development of Radiology in Spain was the inclusion of film reading sessions in the 1965 academic program of the Society of Radiology. It was in the presentation of cases at these conferences that Clinical Radiology found the finest demonstration ground and as a result was immediately adopted by radiologists and progressively applied in scientific meetings, clinical practices and training programs. Its influence was important in reforming hospital practice, legislation on specialization and education, as well as in national health care plans. At the end of the century radiology in Spain was at a par with the standards of other western nations. The author was a witness of the evolution of Radiology during his 50 years of professional life. This article does not pretend to be exhaustive in names or contributions. It is an overview of

  5. Polymorphism of the CTNNB1 and FOXL2 Genes is not Associated with Canine XX Testicular/Ovotesticular Disorder of Sex Development.

    PubMed

    Salamon, Sylwia; Nowacka-Woszuk, Joanna; Switonski, Marek

    2015-01-01

    78,XX testicular or ovotesticular disorder of sex development (DSD) is the most common sex anomaly in dogs, but its molecular background remains unknown. It was hypothesized that the causative mutation may reside in canine chromosome 23 (CFA23), where two genes playing a pivotal role in ovarian development (CTNNB1 and FOXL2) are located. The aim of our study was to search for polymorphism in both candidate genes in 15 DSD dogs (78,XX and a lack of the SRYgene) and 29 normal females. Altogether, 7 novel polymorphic variants were identified: 5 SNPs in CTNNB1 and 2 indels in the FOXL2 gene. The distribution of the identified variants was similar in the DSD and control dogs. Therefore, we concluded that the conducted research did not prove an association between these polymorphisms and canine testicular or ovotesticular XX DSD.

  6. 47,XX,+der(18),t(9;18)(p24;q21) mat: a distinct partial trisomy 18q--syndrome?

    PubMed Central

    Bass, H N; Weber-Parisi, F; Sparkes, R S

    1978-01-01

    A moderately retarded girl had a 47,XX,+der(18),t(9;18)(p24;q21)mat abnormality that was inherited from her mother, who had a 46,XX,t(9;18)(p24;q21) karyotype in most cells, and a minor cell line of 47,XX,+der(18),-t(9;18)(p24;q21). Her dysmorphic features--bilateral epicanthic folds, low-set, abnormal ears, low posterior hairline, clinodactyly of the 5th fingers, and broad great toes--were similar to those of other patients with an additional number 18 chromosome in which all or most of the long arm was missing, thus raising the possibility of a distinct syndrome. Images PMID:739531

  7. Gender Role, Gender Identity and Sexual Orientation in CAIS ("XY-Women") Compared With Subfertile and Infertile 46,XX Women.

    PubMed

    Brunner, Franziska; Fliegner, Maike; Krupp, Kerstin; Rall, Katharina; Brucker, Sara; Richter-Appelt, Hertha

    2016-01-01

    The perception of gender development of individuals with complete androgen insensitivity syndrome (CAIS) as unambiguously female has recently been challenged in both qualitative data and case reports of male gender identity. The aim of the mixed-method study presented was to examine the self-perception of CAIS individuals regarding different aspects of gender and to identify commonalities and differences in comparison with subfertile and infertile XX-chromosomal women with diagnoses of Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS) and polycystic ovary syndrome (PCOS). The study sample comprised 11 participants with CAIS, 49 with MRKHS, and 55 with PCOS. Gender identity was assessed by means of a multidimensional instrument, which showed significant differences between the CAIS group and the XX-chromosomal women. Other-than-female gender roles and neither-female-nor-male sexes/genders were reported only by individuals with CAIS. The percentage with a not exclusively androphile sexual orientation was unexceptionally high in the CAIS group compared to the prevalence in "normative" women and the clinical groups. The findings support the assumption made by Meyer-Bahlburg ( 2010 ) that gender outcome in people with CAIS is more variable than generally stated. Parents and professionals should thus be open to courses of gender development other than typically female in individuals with CAIS.

  8. Cytogenetic Investigation in a Group of Ten Infertile Men with Non-Obstructive Azoospermia: First Algerian 46, XX Syndrome

    PubMed Central

    BAZIZ, Meriem; HAMOULI-SAID, Zohra; RATBI, Ilham; HABEL, Mohamed; GUAOUA, Soukaina; SBITI, Aziza; SEFIANI, Abdelaziz

    2016-01-01

    Background: In Algeria, the data on infertility and its various causes are rare. Recently, the introduction of assisted reproduction has allowed expecting that 300000 couples, which represent 7% of couples of reproductive age, face difficulty conceiving a child. Knowing that most idiopathic cases are likely to be due to chromosomal abnormalities, we aimed to investigate genetic defects by karyotype analysis in Algerian infertile men, using peripheral blood lymphocytes. Methods: A cytogenetic study was conducted on 10 men from infertile couples by Karyotype analysis of R-banding performed by lymphocyte culture technique. Fluorescence in situ hybridization was performed and molecular abnormalities were investigated by polymerase chain reaction. Follicle stimulating hormone (FSH) and luteinizing hormone (LH) levels were evaluated by immunoradiometric method. Results: Chromosomal abnormalities were observed in 30% of the patients. We identified a homogenous Klinefelter syndrome patient with 47, XXY karyotype, a mosaic Klinefelter syndrome patient with 47, XXY/46, XY karyotype and a 46, XX male. Fluorescence in situ hybridization showed that the sex-determining region Y was translocated to the short arm of the X chromosome in patient with 46, XX chromosomal constitution and the presence of the SRY gene was confirmed by polymerase chain reaction and electrophoresis. Conclusion: The occurrence of chromosomal abnormalities in 30% of the infertile men strongly supports the inclusion of routine cytogenetic testing for diagnostic establishment and suitable counseling for couples seeking for assisted reproduction technologies. PMID:27648416

  9. 47,XXX/45,X/46,XX mosaicism in a patient with Turner phenotype and spontaneous puberal development.

    PubMed

    Brambila-Tapia, Aniel Jessica Leticia; Rivera, Horacio; García-Castillo, Herbert; Domínguez-Quezada, Maria Guadalupe; Dávalos-Rodríguez, Ingrid Patricia

    2009-11-01

    To describe a patient with infertility and phenotypic combination of Turner and triple-X syndrome related to mos 47,XXX/45X/46,XX karyotype. Case report. División de Genética, Centro de Investigación Biomédica de Occidente and Hospital de Ginecología y Obstetricia, CMNO, Instituto Mexicano del Seguro Social. The 24-year-old patient presented a phenotypic combination of Turner syndrome and X polysomy. She showed wide and short neck, low posterior hairline, cubitus valgus, bilateral shortening of the fourth and fifth metacarpals, multiple nevi, and müllerian anomalies but had spontaneous pubarche, thelarche, and menarche. Laboratory evaluations, imaging studies, ovarian biopsy, G-banding karyotype, and in situ fluorescence hybridization. Clinical and laboratory findings. A karyotype: mos 47,XXX/45X/46,XX was found in the cytogenetic studies, a bicornuate uterus in the ultrasonographic scan, and a normal ovarian profile in the laboratory tests. The infertility in the present case can be related to either bicornuate uterus or subclinical abortions due to aneuploid ova. Cytogenetic assessment provides important information regarding infertile patients with uterine factors and short stature.

  10. Rare case of massive congenital bilateral chylothorax in a hydropic fetus with true mosaicism 47,XXX/46,XX.

    PubMed

    Cremonini, Giorgio; Poggi, Alice; Capucci, Roberta; Vesce, Fortunato; Patella, Alfredo; Marci, Roberto

    2014-01-01

    Fetal congenital chylothorax is a rare condition that occurs sporadically or can be associated with abnormal karyotype or structural chromosomal anomalies. We report a unique case of fetal congenital bilateral chylothorax associated with mosaicism 47,XXX/46,XX. A female fetus affected by massive bilateral hydrothorax and ascites was diagnosed at 34(+1) weeks of gestation. Previous ultrasonographic exams were completely normal. Immune causes of hydrops were excluded. Elective cesarean section was performed soon after bilateral thoracocentesis. The analysis of drained pleural fluid revealed its lymphatic nature. The fetal karyotyping, performed on chorionic villi at the 11th week, had shown mosaicism 47,XXX/46,XX, later confirmed in the newborn's blood. We hypothesized that chylothorax may be part of the phenotypic spectrum of 47 XXX karyotype and we suggest an ultrasound follow-up of the fetus at closer intervals than the routine timing for this condition, even if it is not usually characterized by severe phenotypic features. © 2013 The Authors. Journal of Obstetrics and Gynaecology Research © 2013 Japan Society of Obstetrics and Gynecology.

  11. Vegetation Structure Changes in the South Part of Western Siberia at the End of XX Century

    NASA Astrophysics Data System (ADS)

    Dyukarev, E.; Pologova, N. N.; Golovatskaya, E. A.; Dyukarev, A. G.; Gordov, E. P.; Okladnikov, I. G.; Titov, A. G.

    2010-12-01

    Understanding human impact on changes in vegetation composition and structure can be performed using analysis of space images obtained from high resolution satellite sensors. Natural ecosystems at the South and Sob-Taiga zone of Western Siberia are characterized by development of an early succession stages, given the projected increase in disturbance, or will be converted into human-dominated terrestrial production systems. Disturbances appear to be increasing in some regions, leading to fragmentation of natural ecosystems and to a generally "weedier," structurally simpler biosphere with fewer systems in a more ecologically complex old-growth state. The analysis of structure of vegetation cover at two test sites located at the south-west part of the West-Siberian Plain in the South and Sub-Taiga zone was made using LANDSAT space images and ground data obtained in various seasons and years. The studied area of the first test site (“Bakchar”) is occupied by bogs, paludificated forests and cultivated lands. Test site “Tomsk” covered by cultivated lands and dark coniferous forest complexes. Vegetation classification was made using NELDA project legend (www.fsl.orst.edu/nelda). The main part of Site “Bakchar” is occupied by tree dominated classes (66%). Wetlands occupy about 43% of the area. Part of herbaceous vegetation is rather low (9%). Site “Tomsk” has completely different structure of classes. More than one-half of the area (52%) is covered by cultivated lands. Forests occupy 42% of the area. Wetlands (9%) exist in the Ob’-Tom’ interfluve and left bank of the Ob’ river. During the XX century the vegetation cover was exposed to natural and anthropogenic changes. Comparison of space images from different years (1990, 1999 and 2007) allowed to reveal dynamics in vegetation cover. Decrease of forest area in 1990-1999 at site “Bakchar” are primary occurs due to intense forest cutting for timber industry and local use. A strong wind have

  12. A rare mosaic interstitial deletion of 7q, 46,XX/46,XX,del(7)(q22.1q31.33), results in a mild clinical phenotype

    SciTech Connect

    Shapira, S.K.; Kochanek, S.; Shaffer, L.G.

    1994-09-01

    Constitutional mosaic structural rearrangements, including deletions, are extremely rare in the population. We present a case of mosaicism for a deletion of chromosome 7q. The patient`s phenotype is much milder than that of non-mosaic patients with a similar deletion of 7q. A 6 and 9/12-year-old Caucasian girl was evaluated because of attention deficit disorder and speech delay. She was born at 38 weeks gestation to her 37 year old G2P2 mother. Her birth weight was 2.2 kg (3rd centile), length was 47 cm (10th-25th centile), and OFC was 30.5 cm (<10th centile). Her motor development was normal. Her speech development was profoundly delayed with her first words spoken at 3 years, and 2-3 word sentences spoken at 5-6 years. At 6 and 9/12 years, she manifested mild mental retardation and profound speech delay, but only mildly dysmorphic features (protuberant ears with under-developed antihelices, flattened forehead, moderate micro-retrognathia). Height, weight, and OFC were at the 10th centile. Chromosomal analysis showed the presence of two cell lines, with 66% of the lymphocytes having a 46,XX pattern and 33% having a 46,XX,del(7)(q22.1q31.33) karyotype. Less than 20 cases of interstitial 7q deletions extending from bands 7q21 or 7q22 to 7q31 or 7q32 have been reported. Our patient represents the first documented case with a mosaic interstitial deletion of chromosome 7q. Furthermore, the deletion resulted in a relatively mild phenotype when compared to reported non-mosaic interstitial 7q deletions, and thus expands the range of clinical heterogeneity that can be anticipated in interstitial deletion patients.

  13. What Does f[subscript xx]f[subscript yy] - f[superscript 2][subscript xy] Greater than 0 "Really" Mean?

    ERIC Educational Resources Information Center

    McCartin, Brian J.

    2008-01-01

    This note presents geometric and physical interpretations of the sufficient condition for a critical point to be a strict relative extremum: f[subscript xx]f[subscript yy] - f[superscript 2][subscript xy] greater than 0. The role of the double derivative f[subscript xy] in this inequality will be highlighted in these interpretations. (Contains 14…

  14. What Does f[subscript xx]f[subscript yy] - f[superscript 2][subscript xy] Greater than 0 "Really" Mean?

    ERIC Educational Resources Information Center

    McCartin, Brian J.

    2008-01-01

    This note presents geometric and physical interpretations of the sufficient condition for a critical point to be a strict relative extremum: f[subscript xx]f[subscript yy] - f[superscript 2][subscript xy] greater than 0. The role of the double derivative f[subscript xy] in this inequality will be highlighted in these interpretations. (Contains 14…

  15. 49 CFR 1242.73 - Cleaning car interiors and freight lost and damaged-all other (accounts XX-53-70 and 51-53-00).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Cleaning car interiors and freight lost and damaged-all other (accounts XX-53-70 and 51-53-00). 1242.73 Section 1242.73 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) ACCOUNTS, RECORDS AND REPORTS...

  16. 49 CFR 1242.73 - Cleaning car interiors and freight lost and damaged-all other (accounts XX-53-70 and 51-53-00).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 9 2014-10-01 2014-10-01 false Cleaning car interiors and freight lost and damaged-all other (accounts XX-53-70 and 51-53-00). 1242.73 Section 1242.73 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) ACCOUNTS, RECORDS AND REPORTS...

  17. 49 CFR 1242.73 - Cleaning car interiors and freight lost and damaged-all other (accounts XX-53-70 and 51-53-00).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 9 2012-10-01 2012-10-01 false Cleaning car interiors and freight lost and damaged-all other (accounts XX-53-70 and 51-53-00). 1242.73 Section 1242.73 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) ACCOUNTS, RECORDS AND REPORTS...

  18. 49 CFR 1242.73 - Cleaning car interiors and freight lost and damaged-all other (accounts XX-53-70 and 51-53-00).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 9 2011-10-01 2011-10-01 false Cleaning car interiors and freight lost and damaged-all other (accounts XX-53-70 and 51-53-00). 1242.73 Section 1242.73 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT OF TRANSPORTATION (CONTINUED) ACCOUNTS, RECORDS AND REPORTS...

  19. [Apparent internal male pseudo-hermaphroditism. Gynecomastia. Negative gonad surgical research. Caryotype 46, XX. Presence of H-Y antigen (author's transl)].

    PubMed

    Vague, J; Guidon, J; Mattei, J F; Luciani, J M; Jouve, R; Le Gall, F

    1977-01-01

    Boy 15. Aspect of delayed puberty with empty scrotum and gynecomastia. Caryotype 46, XX. Presence of H.Y. Antigen. Plasmatic testosterone 1 020 pg/ml. Normal plasmatic FSH and LH. Hypotrophic uterus and tubes. No gonad found. Small right epididymis. Complete virilization by testosterone.

  20. Sox10 gain-of-function causes XX sex reversal in mice: implications for human 22q-linked disorders of sex development.

    PubMed

    Polanco, Juan Carlos; Wilhelm, Dagmar; Davidson, Tara-Lynne; Knight, Deon; Koopman, Peter

    2010-02-01

    Male development in mammals is normally initiated by the Y-linked gene Sry, which activates expression of Sox9, leading to a cascade of gene activity required for testis formation. Although defects in this genetic cascade lead to human disorders of sex development (DSD), only a dozen DSD genes have been identified, and causes of 46,XX DSD (XX maleness) other than SRY translocation are almost completely unknown. Here, we show that transgenic expression of Sox10, a close relative of Sox9, in gonads of XX mice resulted in development of testes and male physiology. The degree of sex reversal correlated with levels of Sox10 expression in different transgenic lines. Sox10 was expressed at low levels in primordial gonads of both sexes during normal mouse development, becoming male-specific during testis differentiation. SOX10 protein was able to activate transcriptional targets of SOX9, explaining at a mechanistic level its ability to direct male development. Because over-expression of SOX10 alone is able to mimic the XX DSD phenotypes associated with duplication of human chromosome 22q13, and given that human SOX10 maps to 22q13.1, our results functionally implicate SOX10 in the etiology of these DSDs.

  1. Semiempirical calculation of radiative constants in the spectra of nickel-like ions Kr IX, Sr XI, Y XII, Ru XVII, Pd XIX, and Ag XX

    NASA Astrophysics Data System (ADS)

    Loginov, A. V.

    2015-03-01

    The probabilities of the electric-dipole transitions 3 d 94 p, 3 d 94 f-3 d 10, 3 d 94 s, and 3 d 94 d in the spectra of nickel-like ions Kr IX, Sr XI, Y XII, Ru XVII, Pd XIX, and Ag XX are calculated semiempirically with the use of published energy levels.

  2. An ab initio approach on superconducting properties of Mo3X(X = Si,Ga,Ge) compounds

    NASA Astrophysics Data System (ADS)

    Subhashree, G.; Sankar, S.; Krithiga, R.

    2015-06-01

    Self-consistent first principles calculations on type II weakly coupled superconducting Mo3X(X = Si,Ga,Ge) compounds of A15 phase are performed to understand their fundamental characteristics of the electronic, thermal and superconducting properties. The bulk modulus (B), Debye temperature (θD), density of states (DOS) (N(EF)), electron-phonon coupling constant (λ), superconducting transition temperature (Tc), and electronic specific heat coefficient (γ) have been computed in terms of the electronic structure results, obtained by using the tight-binding linear muffin-tin orbital method. It is observed that all the three materials have their electronic properties dominated by d-orbital at Fermi energy. Thermal and superconducting properties calculated here are found to corroborate well with the experimental results of literature.

  3. p-Electron Magnetism in anion doped BaTiO3-xXx (X=C,N,B)

    NASA Astrophysics Data System (ADS)

    Gruber, Christoph; Osvaldo Bedolla Velazquez, Pedro; Redinger, Josef; Mohn, Peter; Marsman, Martijn

    2012-02-01

    We present VASP calculations using the HSE functional for carbon, nitrogen, and boron doped BaTiO3-xXx (X=C,N,B). We calculate a 40-atom supercell and replace one oxygen atom by C,N, or B. For all three substituents we find a magnetically ordered groundstate which is insulating for C and N and halfmetallic for B. The changes in the electronic structure between the undoped and the doped case are dominated by the strong crystal field effects together with the large band splitting for the impurity p-bands. Using an MO picture we give an explanation for the pronounced changes in the electronic structure between the insulating non-magnetic state and the as well insulating magnetic state for doped BaTiO3. p-element doped perovskites could provide a new class of materials for various applications ranging from spin-electronics to magneto-optics.

  4. Phase gap in pseudoternary R1-yRy'Mn2X2-xXx' compounds

    NASA Astrophysics Data System (ADS)

    Wang, J. L.; Kennedy, S. J.; Campbell, S. J.; Hofmann, M.; Dou, S. X.

    2013-03-01

    Our neutron diffraction investigation of PrMn2Ge2-xSix reveals a clear separation into two magnetic phases, canted ferromagnetic (Fmc) and antiferromagnetic (AFmc), between x = 1.0 and 1.2 and a commensurate phase gap in the lattice, due to magnetostrictive distortion. This remarkable magnetoelastic phenomenon is driven by a nonuniform atomic distribution on the X site which in turn produces subtle variations in the local lattice and abrupt changes in the Mn-Mn magnetic exchange interaction. Our results show that coexistence of Fmc and AFmc phases depends on lattice parameter, chemical pressure from the rare-earth and metalloid sites, and local lattice strain distributions. We demonstrate that these magnetostructural correlations act across the entire family of R1-yRy'Mn2X2-xXx' compounds.

  5. Laboratory Measurements of 3 --> 2 X-ray Line Ratios of F-like Fe XVIII and Ni XX

    SciTech Connect

    Gu, M F; Chen, H; Brown, G V; Beiersdorfer, P; Kahn, S M

    2007-03-08

    The intensity ratios of 3 {yields} 2 emission lines of Fe XVIII and Ni XX were measured on the Livermore electron beam ion trap (EBIT-I) with a flat-field grating spectrometer. The results were compared with distorted-wave (DW) calculations obtained with the Flexible Atomic Code and recent close-coupling calculations using the R-matrix code. The measured 3s {yields} 2p/3d {yields} 2p ratios are about 20-40% higher than the theoretical values. When more extended configuration interaction is included in the DW theory, the agreement with the measurements improved slightly. At the beam energies of these measurements, no significant resonance contribution is expected to be present, and the discrepancies represent the uncertainties in the direct excitation cross sections.

  6. [The major achievements of medicine in XX-early XXI centuries and their significance for the near future].

    PubMed

    Lisitsyn, Iu P; Zhuravleva, T V

    2012-01-01

    Among major achievements of medicine in XX-early XXI centuries considered as the most outstanding contribution are the development of theory of system of control of functions of organism and its integrity by I.P. Pavlov and his disciples and followers: the concept of psycho-somatic medicine by Z. Freud and social psychology; the theory of stress and general adaptive syndrome by H. Selye and the discovering of nature of many infectious and parasitic diseases. Then establishment of pathogenic impact of extra-environmental factors, decoding of gene chromosomal structure of organism, development of genetic engineering, effective pharmaceuticals, and techniques of treatment and prevention of various inherent and acquired diseases also can be put into this category. The achievements and discoveries in the area of public health, social medicine and hygiene and development of concept of healthy life-style are discussed too.

  7. 75 FR 2826 - Airworthiness Directives; Sicma Aero Seat 88xx, 89xx, 90xx, 91xx, 92xx, 93xx, 95xx, and 96xx...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-19

    ... INFORMATION CONTACT: Jeffrey Lee, Aerospace Engineer, Boston Aircraft Certification Office, FAA, Engine..., CL-601-3R, and CL- 604) Airplanes. Bombardier, Inc CL-600-2B19 (Regional Jet Series 100 & 440) Airplanes. Bombardier, Inc CL-600-2C10 (Regional Jet Series 700, 701, & 702) Airplanes. Bombardier, Inc CL...

  8. 76 FR 22830 - Airworthiness Directives; Sicma Aero Seat 88xx, 89xx, 90xx, 91xx, 92xx, 93xx, 95xx, and 96xx...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-25

    ... Lee, Aerospace Engineer, Boston Aircraft Certification Office, FAA, Engine & Propeller Directorate, 12...-604) Airplanes. Bombardier, Inc CL-600-2B19 (Regional Jet Series 100 and 440) Airplanes. Bombardier, Inc CL-600-2C10 (Regional Jet Series 700, 701, and 702) Airplanes. Bombardier, Inc CL-600-2D15...

  9. The study of the hydrological regime extreme effects of the Caspian Sea during the XX-XXI centuries

    NASA Astrophysics Data System (ADS)

    Yaitskaya, Natalia

    2016-04-01

    The Caspian Sea - the unique largest enclosed inland body of water on Earth. Significant periodic sea level fluctuations are a typical feature of the sea. In the XIX-XX centuries a number of comprehensive studies of the Caspian Sea was carried out. The results are published in the papers, monographs and climatic atlases. But a number of fundamental questions about the features of the hydrological regime of the Caspian Sea is still open: 1. How does the water circulation change during the level variations? 2. What is the effect of heterogeneity of evaporation from the water surface on the formation of the flow field in the conditions of long-term level changes? 3. How does the water salinity regime change depending on the sea level position, water circulation, river flow and different climatic influences? 4. What is the effect of extreme events (multi-hazards) (ice, storms, destruction of the coasts) on coastal infrastructure? In 2016, the project aims to study hydrological regime extreme effects of the Caspian Sea was supported by the Russian Foundation for Basic Research. Within this project all of the above problems will be solved. Geographic information system "Caspian Sea" for the storage and data processing, including a database of primary oceanographic information for the period of instrumental observations (1897-2013), cartographic database (1921-2011) and tools for multidimensional analysis of spatio-temporal information is the basis of the study. The scheme of interconnected hydrodynamic models (Caspian Sea MODel - Ocean Model - Wind wave model) was developed. The important factors are taken into account in the structure of the models: long-term and seasonal dynamics of the sea waves parameters, new long-term values of evaporation from the shallow waters areas of the Caspian Sea, water circulation. Schemes of general seasonal circulation of the Caspian Sea and the Northern Caspian at different positions of the sea level in XX-XXI centuries using

  10. High resolution X-ray spectra of solar flares. V - Interpretation of inner-shell transitions in Fe XX-Fe XXIII

    NASA Technical Reports Server (NTRS)

    Doschek, G. A.; Feldman, U.; Cowan, R. D.

    1981-01-01

    The paper examines high-resolution solar flare iron line spectra recorded between 1.82 and 1.97 A by a spectrometer flown by the Naval Research Laboratory on an Air Force spacecraft launched on 1979 February 24. The emission line spectrum is due to inner-shell transitions in the ions Fe XX-Fe XXV. Using theoretical spectra and calculations of line intensities obtained by methods discussed by Merts, Cowan, and Magee (1976), electron temperatures as a function of time for two large class X flares are derived. These temperatures are deduced from intensities of lines of Fe XXII, Fe XXIII, and Fe XXIV. The determination of the differential emission measure between about 12-million and 20-million K using these temperatures is considered. The possibility of determining electron densities in flare and tokamak plasmas using the inner-shell spectra of Fe XXI and Fe XX is discussed.

  11. Low-level 45,X/46,XX mosaicism is not associated with congenital heart disease and thoracic aorta dilatation:prospective magnetic resonance imaging and ultrasound study.

    PubMed

    Klásková, E; Tüdös, Z; Sobek, A; Zapletalová, J; Dostál, J; Zbořilová, B; Sobek, A; Adamová, K; Lattová, V; Dostálová, Z; Procházka, M

    2015-06-01

    To establish the prevalence of risk factors for aortic dissection, such as bicuspid aortic valve, aortic coarctation and ascending aorta dilatation, in women with low-level 45,X/46,XX mosaicism undergoing an in-vitro fertilization (IVF) procedure. The study group comprised 25 women with low-level 45,X/46,XX mosaicism (ranging from 3.3% to 10.0%) who were referred to two reproductive medicine units between 2009 and 2013 because of infertility and who underwent subsequent karyotyping. In accordance with the recommendation of the Practice Committee of the American Society for Reproductive Medicine for patients with Turner syndrome (TS), prior to the IVF procedure, all women underwent careful cardiovascular screening for congenital heart disease and thoracic aorta dilatation, including standard cardiac examination, echocardiography and non-contrast cardiac magnetic resonance imaging. Aortic size index (ASI, diameter of the ascending aorta normalized to body surface area) and the prevalence of coarctation of the aorta and of bicuspid aortic valve were compared with findings previously reported in women with TS and the general population. Bicuspid aortic valve without any stenosis or regurgitation was found in one woman in the study group with low-level 45,X/46,XX mosaicism, a statistically significantly lower prevalence of bicuspid aortic valve than that reported in women with TS. Aortic coarctation was not identified in any individual. The ASI was below the  95th percentile in all cases and the mean value was significantly lower than the mean reference values for both the general population and women with TS. Compared with the general population, the prevalence of risk factors for aortic dissection was not found to be higher in women with low-level 45,X/46,XX mosaicism without any noticeable features except infertility. Copyright © 2014 ISUOG. Published by John Wiley & Sons Ltd.

  12. [From the history of organization of medical care to population in cities of the north-eastern Caucasus in XIX--early XX centuries].

    PubMed

    2013-01-01

    The article deals with becoming of urban health care in the region of the north-eastern Caucasus in XIX--early XX centuries. The characteristics and stages of development of medical care in cities appeared grew from military fortifications and fortresses in the meddle of XIX century are established. The first curative institutions in cities were military hospitals and infirmaries. Later on appeared clinics of philanthropic societies and even later on hospitals functioning on municipality funds and private curative establishments.

  13. Proceedings of the Twentieth NASA Propagation Experimenters Meeting (NAPEX XX) and the Advanced Communications Technology Satellite (ACTS) Propagation Studies Miniworkshop

    NASA Technical Reports Server (NTRS)

    Golshan, Nassar (Editor)

    1996-01-01

    The NASA Propagation Experimenters (NAPEX) Meeting and associated Advanced Communications Technology Satellite (ACTS) Propagation Studies Miniworkshop convene yearly to discuss studies supported by the NASA Propagation Program. Representatives from the satellite communications (satcom)industry, academia, and government with an interest in space-ground radio wave propagation have peer discussion of work in progress, disseminate propagation results, and interact with the satcom industry. NAPEX XX, in Fairbanks, Alaska, June 4-5, 1996, had three sessions: (1) "ACTS Propagation Study: Background, Objectives, and Outcomes," covered results from thirteen station-years of Ka-band experiments; (2) "Propagation Studies for Mobile and Personal Satellite Applications," provided the latest developments in measurement, modeling, and dissemination of propagation phenomena of interest to the mobile, personal, and aeronautical satcom industry; and (3)"Propagation Research Topics," covered a range of topics including space/ground optical propagation experiments, propagation databases, the NASA Propagation Web Site, and revision plans for the NASA propagation effects handbooks. The ACTS Miniworkshop, June 6, 1996, covered ACTS status, engineering support for ACTS propagation terminals, and the ACTS Propagation Data Center. A plenary session made specific recommendations for the future direction of the program.

  14. XX/XO, a rare sex chromosome system in Potamotrygon freshwater stingray from the Amazon Basin, Brazil.

    PubMed

    de Souza Valentim, Francisco Carlos; Porto, Jorge Ivan Rebelo; Bertollo, Luiz Antonio Carlos; Gross, Maria Claudia; Feldberg, Eliana

    2013-09-01

    Potamotrygonidae is a representative family of South American freshwater elasmobranchs. Cytogenetic studies were performed in a Potamotrygon species from the middle Negro River, Amazonas, Brazil, here named as Potamotrygon sp. C. Mitotic and meiotic chromosomes were analyzed using conventional staining techniques, C-banding, and detection of the nucleolus organizing regions (NOR) with Silver nitrate (Ag-NOR). The diploid number was distinct between sexes, with males having 2n = 67 chromosomes, karyotype formula 19m + 8sm + 10st + 30a, and fundamental number (FN) = 104, and females having 2n = 68 chromosomes, karyotype formula 20m + 8sm + 10st + 30a, and FN = 106. A large chromosome, corresponding to pair number two in the female karyotype, was missing in the male complement. Male meiotic cells had 33 bivalents plus a large univalent chromosome in metaphase I, and n = 33 and n = 34 chromosomes in metaphase II. These characteristics are consistent with a sex chromosome system of the XX/XO type. Several Ag-NOR sites were identified in both male and female karyotypes. Positive C-banding was located only in the centromeric regions of the chromosomes. This sex chromosome system, which rarely occurs in fish, is now being described for the first time among the freshwater rays of the Amazon basin.

  15. Insulin and IGF1 Receptors Are Essential for XX and XY Gonadal Differentiation and Adrenal Development in Mice

    PubMed Central

    Romero, Yannick; Conne, Béatrice; Truong, Vy; Papaioannou, Marilena D.; Schaad, Olivier; Docquier, Mylène; Herrera, Pedro Luis; Wilhelm, Dagmar; Nef, Serge

    2013-01-01

    Mouse sex determination provides an attractive model to study how regulatory genetic networks and signaling pathways control cell specification and cell fate decisions. This study characterizes in detail the essential role played by the insulin receptor (INSR) and the IGF type I receptor (IGF1R) in adrenogenital development and primary sex determination. Constitutive ablation of insulin/IGF signaling pathway led to reduced proliferation rate of somatic progenitor cells in both XX and XY gonads prior to sex determination together with the downregulation of hundreds of genes associated with the adrenal, testicular, and ovarian genetic programs. These findings indicate that prior to sex determination somatic progenitors in Insr;Igf1r mutant gonads are not lineage primed and thus incapable of upregulating/repressing the male and female genetic programs required for cell fate restriction. In consequence, embryos lacking functional insulin/IGF signaling exhibit (i) complete agenesis of the adrenal cortex, (ii) embryonic XY gonadal sex reversal, with a delay of Sry upregulation and the subsequent failure of the testicular genetic program, and (iii) a delay in ovarian differentiation so that Insr;Igf1r mutant gonads, irrespective of genetic sex, remained in an extended undifferentiated state, before the ovarian differentiation program ultimately is initiated at around E16.5. PMID:23300479

  16. Chromosome banding in Amphibia. XXIX. The primitive XY/XX sex chromosomes of Hyla femoralis (Anura, Hylidae).

    PubMed

    Schmid, M; Steinlein, C

    2003-01-01

    The karyotype of the pine woods treefrog, Hyla femoralis, is characterized by primitive XY female/XX male sex chromosomes. The sole difference between the X and the Y is the presence of a nucleolus organizer region (NOR) in the X. Due to a deletion of the NOR in the Y, this chromosome is distinctly smaller than the X. Since no autosomal NORs exist in the karyotype of this species, the NOR deletion in the Y results in a sex-specific difference in the number of ribosomal RNA genes, with a female:male ratio of about 2:1. Interphase nuclei of male animals contain always one silver-stained nucleolus, whereas most nuclei of female specimens exhibit two nucleoli. This is in agreement with the absence of dosage compensation for sex-linked genes in amphibian cells. The consequences of the loss of about 50% of ribosomal RNA genes for the viability of male individuals and spermatogenesis are discussed. Copyright 2003 S. Karger AG, Basel

  17. Identification by FISH of 21q22 duplication in patient with Down syndrome and apparent 46,XX karyotype

    SciTech Connect

    Yu, Chih-yu; Anyane-Yeoba, K.; Warburton, D.

    1994-09-01

    Karyotype analysis of a 3-day-old child referred for clinical evaluation of Down syndrome was originally reported as normal 46,XX. The child had many features of Down syndrome, including a leukemoid reaction at birth. Because of the strongly suggestive clinical features, and a slightly unusual appearance of the short arm of one chromosome 21, FISH analysis was carried out using a probe specific for the 21q22.3 region (ONCOR). Signal was seen as expected in the distal long arm of both chromosomes 21, but also in the short arm with the morphological variant. DNA analysis with a number of long arm probes confirmed the presence of duplication of a large portion of band 21q22. Parental karyotypes were normal. The mother of this case had declined amniocentesis. However, it is very likely that routine prenatal chromosome analysis would not have detected the duplication, since the short arm was not strikingly different from many normal variants. Only screening with a 21q22 FISH probe (interphase or metaphase) would have predicted the Down syndrome in this child.

  18. Energy levels, oscillator strengths, and radiative rates for Si-like Zn XVII, Ga XVIII, Ge XIX, and As XX

    SciTech Connect

    Abou El-Maaref, A.; Allam, S.H.; El-Sherbini, Th.M.

    2014-01-15

    The energy levels, oscillator strengths, line strengths, and transition probabilities for transitions among the terms belonging to the 3s{sup 2}3p{sup 2}, 3s3p{sup 3}, 3s{sup 2}3p3d, 3s{sup 2}3p4s, 3s{sup 2}3p4p and 3s{sup 2}3p4d configurations of silicon-like ions (Zn XVII, Ga XVIII, Ge XIX, and As XX) have been calculated using the configuration-interaction code CIV3. The calculations have been carried out in the intermediate coupling scheme using the Breit–Pauli Hamiltonian. The present calculations have been compared with the available experimental data and other theoretical calculations. Most of our calculations of energy levels and oscillator strengths (in length form) show good agreement with both experimental and theoretical data. Lifetimes of the excited levels have also been calculated. -- Highlights: •We have calculated the fine-structure energy levels of Si-like Zn, Ga, Ge and As. •The calculations are performed using the configuration interaction method (CIV3). •We have calculated the oscillator strengths, line strengths and transition rates. •The wavelengths of the transitions are listed in this article. •We also have made comparisons between our data and other calculations.

  19. Dose distribution analysis of physical and dynamic wedges by using an intensity-modulated radiotherapy MatriXX

    NASA Astrophysics Data System (ADS)

    Lee, Hae-Kag; Cho, Jae-Hwan; Cho, Dae-chul

    2013-05-01

    This study investigated differences between the physical wedge and the dynamic wedge distributions of radiation by using an intensity-modulated radiotherapy (ImRT) MatriXX. The linear accelerator used X-rays with energy levels of 6 MV and 10 MV to adjust the collimator by motoring the independent jaws (X1, X2, Y1, Y2) for setting wedge angles of 15, 30, 45, and 60 degrees. The collimator field size was set as 10 × 10 cm2 or 20 × 20 cm2 at the maximum dose point. The dose distribution for each wedge had ±5% and ±11% errors for field sizes of 10 × 10 cm2 and 20 × 20 cm2, respectively. The error was greatest at a wedge angle of 45 degrees and was pronounced at the end of the dynamic wedge where Y1 and Y2 met. Consequently, concluded that the dose distributions were similar for both wedges for the field size of a small beam profile. The beam dose was greatly increased at the end of the dynamic wedge. A more precise estimate of the therapeutic dose of radiation for a dynamic wedge that nearly matches that of the physical wedge can be achieved by correcting of the increasing part of the beam dose. The findings imply that a heavy wedge filter should not be used when calculating the isodose distribution and the therapeutic dose.

  20. Advances in performance and beam quality of 9xx-nm laser diodes tailored for efficient fiber coupling

    NASA Astrophysics Data System (ADS)

    Lauer, Christian; König, Harald; Grönninger, Günther; Hein, Sebastian; Gomez-Iglesias, Alvaro; Furitsch, Michael; Maric, Josip; Kissel, Heiko; Wolf, Paul; Biesenbach, Jens; Strauss, Uwe

    2012-03-01

    The impact of new direct-diode and fiber laser systems on industrial manufacturing drives the demand for highbrightness diode laser pump sources suitable for simple fiber coupling with high efficiency. Within the German funded project HEMILAS laser mini-bars with different bar geometries and small fill factors were investigated. We present results on 9xx nm bars with tailored beam parameter products for simplified coupling to fibers with core diameters of 200μm and 300μm with a numerical aperture of 0.22 and compare beam quality parameters, brightness, conversion efficiency, and thermal performance of different bar designs. Optimized epitaxy structures yield conversion efficiency maxima above 66%. The slow axis divergence angle of mini-bars with a fill factor of 10% featuring five 100μm wide and 4mm long emitters based on this epitaxy structure stays below 7°, which corresponds to a beam parameter product of 15mm mrad, up to very high output power of over 45W. This result was achieved for mounting on actively cooled submounts using hard solder. A similar bar with 5mm cavity length and using soft soldering reached an output power of 60W at the same beam parameter product. At 4mm cavity length, no COMD failures were observed up to currents exceeding the thermal rollover and the maximum output cw power was 95W.

  1. Magnetoelectric effects in the spin 1/2 XX chain with three spin interactions and Dzyaloshinskii-Moriya interaction

    NASA Astrophysics Data System (ADS)

    Durganandini, P.

    We consider the spin 1/2 XX chain with three spin interactions of the XZX+YXY and XZY-YZX types in an external magnetic field and with Dzyaloshinskii-Moriya (D-M) interaction. Interpreting the D-M interaction as a local electric polarization, we study the magnetoelectric effects in the system by using the exact solution of the problem. We obtain the ground state phase diagram by calculating the electric polarization, magnetization and isentropes. There are various regimes of magnetic and electric polarization depending on the relative strengths of the three spin interaction as well as that of the external fields. For a certain range of three spin interaction strengths, the system shows the existence of finite magnetization and electric polarization even in the absence of any external fields. The external electric and magnetic fields modify the ground state phases and can be used to tune the various regimes. We also calculate the entropy and analyze the electrocaloric and magnetocaloric effects. We show that the electrocaloric and magnetocaloric effects can be used to obtain information about the magnetoelectric effects in the system. I thank DST, India for financial support through research grant.

  2. Review of Outcome Information in 46,XX Patients with Congenital Adrenal Hyperplasia Assigned/Reared Male: What Does It Say about Gender Assignment?

    PubMed

    Lee, Peter A; Houk, Christopher P

    2010-01-01

    There is ample historical verification of 46,XX congenital adrenal hyperplasia (CAH) patients being born with essentially male genitaliawhile outcome information is scant. Prior to glucocorticoid therapy, most patients died very young from adrenal insufficiency. Most available reports from laterchildhood, contain little information concerning sexual identity. Reports on older individuals lack adequate information about sexual identity and quality of life. The difficulty in assessing the relative impact of multiple dynamic environmental factors on the development of sexual identity, self- and body esteem and overall adjustment to life is clear. Nevertheless, it remains unclear whether those infants whose masculine genitalia at birth resulted in an initial male assignment would have enjoyed a better adult outcome had they been allowed to remain male rather than the female reassignment that most received. Further, one could ask whether a male sex of rearing should be considered in 46,XX CAH infants with male external genitalia. After reviewing available literature, we conclude that because those extremely virlized 46,XX CAH patients who were reared male with healthy social support demonstrated satisfactory levels of social and sexual function as adults a male sex assignment should be considered in these types of infants when social and cultural environment are supportive.

  3. Chromosome analysis in Pseudopaludicola (Anura, Leiuperidae), with description of sex chromosomes XX/XY in P. saltica.

    PubMed

    Duarte, Thiago C; Veiga-Menoncello, Ana Cristina P; Lima, Janaína F R; Strüssmann, Christine; Del-Grande, Maria L; Giaretta, Ariovaldo A; Pereira, Emiliane G; Rossa-Feres, Denise C; Recco-Pimentel, Shirlei M

    2010-04-01

    Taxonomic changes have frequently occurred in the anuran genus Pseudopaludicola as a consequence of high morphological similarity among its species. The present work reports karyotypic analysis of three Pseudopaludicola species sampled in their type locality and four Pseudopaludicola populations from distinct localities, aiming at contributing to the systematics of this genus. Chromosomes were stained with Giemsa or submitted to the silver staining (Ag-NOR) and C-banding techniques. The karyotype was 2n=22 in P. mineira, Pseudopaludicola sp. and two populations of P. saltica. The chromosome pair 8 was heteromorphic in P. saltica, characterizing a XX/XY sex-determination system with telocentric X and submetacentric Y. Highly similar karyotypes with 2n=18 chromosomes were observed in P. canga, P. aff. canga from Barreirinhas, State of Maranhão, Uberlândia, State of Minas Gerais and Icém, State São Paulo. The high similarity among the karyotypes 2n=18 suggested that the populations of P. aff. canga belong to the group 'pusilla', the same group of P. canga. The data demonstrated also that P. aff. canga from Barreirinhas (northeast region) is cytogenetically identical to P. canga with regarding the NOR site position in pair 3 and the presence of a heterochromatic block in the pair 2, whereas P. aff. canga from Uberlândia and Icém (southeast) had the NOR in the pair 9. Moreover, the cytogenetic data discriminated P. mineira and Pseudopaludicola sp. from the previously analyzed species with 22 chromosomes, and suggested that Pseudopaludicola sp. is an undescribed species. Sexual heteromorphic chromosomes are firstly reported in Pseudopaludicola and the data indicated the need of an extensive taxonomic review in this genus.

  4. SU-E-T-413: Examining Acquisition Rate for Using MatriXX Ion Chamber Array to Measure HDR Brachytherapy Treatments

    SciTech Connect

    Wagar, M; Bhagwat, M; O’Farrell, D; Friesen, S; Buzurovic, I; Damato, A; Devlin, P; Cormack, R

    2015-06-15

    Purpose: There are unique obstacles to implementing the MatriXX ionchamber array as a QA tool in Brachytherapy given that the device is designed for use in the MV energy range. One of the challenges we investigate is the affect of acquisition rates on dose measurement accuracy for HDR treatment plans. Methods: A treatment plan was optimized in Oncentra Brachy TPS to deliver a planar dose to a 5×5cm region at 10mm depth. The applicator was affixed to the surface of the MatriXX array. The plan was delivered multiple times using a Nucleatron HDR afterloader with a 2.9Ci Ir192 source. For each measurement the sampling rate of the MatriXX movie mode was varied (30ms and 500ms). This experiment was repeated with identical parameters, following a source exchange, with an 11.2Ci Ir192 source. Finally, a single snap measurement was acquired. Analysis was preformed to evaluate the fidelity of the dose delivery for each iteration of the experiment. Evaluation was based on the comparison between the measured and TPS predicted dose. Results: Higher sample rates induce a greater discrepancy between the predicted and measured dose. Delivering the plan using a lower activity source also produced greater discrepancy in the measurement due to the increased delivery time. Analyzing the single snap measurement showed little difference from the 500ms integral dose measurement. Conclusion: The advantage of using movie mode for HDR treatment delivery QA is the ability for real time source tracking in addition to dose measurement. Our analysis indicates that 500ms is an optimal frame rate.

  5. Normal growth and normalization of hypergonadotropic hypogonadism in atypical Turner syndrome (45,X/46,XX/47,XXX). Correlation of body height with distribution of cell lines.

    PubMed

    Partsch, C J; Pankau, R; Sippell, W G; Tolksdorf, M

    1994-06-01

    A comparison has been made of a case with 45,X/46,XX/47,XXX mosaicism with some 50 cases in the literature. A significant positive correlation was found between height standard deviation scores of mosaic patients from the literature and the frequency of cells with a normal chromosome constitution (n = 21, rs = 0.552, P < 0.01). In contrast, a significant negative correlation was seen between body height and the frequency of cells with a 45,X constitution (n = 21, rs = -0.594, P < 0.01). There was no significant correlation of height standard deviation score with the 47,XXX cell line (n = 21, rs = -0.353). A patient with a rare chromosomal mosaicism (45,X/46,XX/47,XXX) is described. The diagnosis was first made by chromosome analysis in amniotic cells. The patient showed no symptoms suggestive of Turner syndrome and growth followed the 75th height percentile. Basal and gonadotropin-releasing hormone stimulated gonadotropin levels normalized after age 4.8 years and did not subsequently return to hypergonadotropic levels. In blood lymphocytes, there was an increase in the frequency of cells with a normal chromosome constitution over 9 years. This in vivo cell selection is discussed. Chromosome analysis in skin fibroblasts showed the same triple mosaicism with a similar distribution of cell lines as in blood lymphocytes. In conclusion, statistical evidence was demonstrated that the severity of short stature is correlated with the distribution of cell lines in 45,X/46,XX/47,XXX mosaicism. This finding is of importance for the genetic counselling in cases of prenatal diagnosis of mosaic Turner syndrome.

  6. Coexistence of gonadal dysgenesis and Mayer-Rokitansky-Kuster-Hauser syndrome in 46, XX female: A case report and review of literature.

    PubMed

    Shah, Viral N; Ganatra, Parth J; Parikh, Rajni; Kamdar, Panna; Baxi, Seema; Shah, Nishit

    2013-10-01

    The association of gonadal dysgenesis and Mayer-Rokitansky-Kuster-Hauser syndrome is very rare. We report a 21-year-old phenotypical female who presented with primary amenorrhea and underdeveloped secondary sexual characteristics. Hormonal evaluation revealed hypergonadotropic hypogonadism. Her karyotype was 46XX. Laparoscopy of pelvis revealed absent uterus, normal fallopian tubes and bilateral streak ovaries, which were biopsied and histopathology was consistent with the findings of gonadal dysgenesis. We searched PubMed for similar reports in the literature and details of all the cases were analyzed and reported here.

  7. Coexistence of gonadal dysgenesis and Mayer-Rokitansky-Kuster-Hauser syndrome in 46, XX female: A case report and review of literature

    PubMed Central

    Shah, Viral N.; Ganatra, Parth J.; Parikh, Rajni; Kamdar, Panna; Baxi, Seema; Shah, Nishit

    2013-01-01

    The association of gonadal dysgenesis and Mayer-Rokitansky-Kuster-Hauser syndrome is very rare. We report a 21-year-old phenotypical female who presented with primary amenorrhea and underdeveloped secondary sexual characteristics. Hormonal evaluation revealed hypergonadotropic hypogonadism. Her karyotype was 46XX. Laparoscopy of pelvis revealed absent uterus, normal fallopian tubes and bilateral streak ovaries, which were biopsied and histopathology was consistent with the findings of gonadal dysgenesis. We searched PubMed for similar reports in the literature and details of all the cases were analyzed and reported here. PMID:24251185

  8. Hypospadias in a male (78,XY; SRY-positive) dog and sex reversal female (78,XX; SRY-negative) dogs: clinical, histological and genetic studies.

    PubMed

    Switonski, M; Payan-Carreira, R; Bartz, M; Nowacka-Woszuk, J; Szczerbal, I; Colaço, B; Pires, M A; Ochota, M; Nizanski, W

    2012-01-01

    Hypospadias is rarely reported in dogs. In this study we pre-sent 2 novel cases of this disorder of sexual development and, in addition, a case of hereditary sex reversal in a female with an enlarged clitoris. The first case was a male Moscow watchdog with a normal karyotype (78,XY) and the presence of the SRY gene. In this dog, perineal hypospadias, bilateral inguinal cryptorchidism and testes were observed. The second case, representing the Cocker spaniel breed, had a small penis with a hypospadic orifice of the urethra, bilateral cryptorchidism, testis and a rudimentary gonad inside an ovarian bursa, a normal female karyotype (78,XX) and a lack of the SRY gene. This animal was classified as a compound sex reversal (78,XX, SRY-negative) with the hypospadias syndrome. The third case was a Cocker spaniel female with an enlarged clitoris and internally located ovotestes. Cytogenetic and molecular analyses revealed a normal female karyotype (78,XX) and a lack of the SRY gene, while histology of the gonads showed an ovotesticular structure. This case was classified as a typical hereditary sex reversal syndrome (78,XX, SRY-negative). Molecular studies were focused on coding sequences of the SRY gene (case 1) and 2 candidates for monogenic hypospadias, namely MAMLD1 (mastermind-like domain containing 1) and SRD5A2 (steroid-5-alpha-reductase, alpha polypeptide 2). Sequencing of the entire SRY gene, including 5'- and 3'-flanking regions, did not reveal any mutation. The entire coding sequence of MAMLD1 and SRD5A2 was analyzed in all the intersexes, as well as in 4 phenotypically normal control dogs (3 females and 1 male). In MAMLD1 2 SNPs, including 1 missense substitution in exon 1 (c.128A>G, Asp43Ser), were identified, whereas in SRD5A2 7 polymorphisms, including 1 missense SNP (c.358G>A, Ala120Thr), were found. None of the identified polymorphisms cosegregated with the intersexual phenotype, thus, we cannot confirm that hypospadias may be associated with polymorphism

  9. Hormonal studies in a male with a 47,XXX chromosome constitution: comparison with the hormonal pattern of a 46,XX male and patients with Klinefelter's syndrome.

    PubMed

    Borghi, A; Forti, G; Fusi, S; Bigozzi, U; Giusti, G

    1980-01-01

    Chromosome analysis in peripheral blood lymphocytes and skin fibroblasts of a 18 year old chromatin-positive man showed a 47,XXX karyotype. The following hormonal studies were performed: 1) FSH and LH response to GnRH; 2) hypothalamic-pituitary responsiveness to short-term testosterone administration; 3) plasma levels of testosterone, dihydrotestosterone, 17-hydroxyprogesterone, estradiol before and after hCG stimulation. Results were compared with similar studies performed in a 46,XX male and in a group of patients with Klinefelter's syndrome. Our data support the hypothesis that this rare cytogenetical disorder can be considered, from the endocrine point of view, as a variant of the Klinefelter's syndrome.

  10. Constraint of Baryon Asymmetry on Grand Unified Theories and X-X Mass Splitting Scenario for Baryon Number Generation.

    NASA Astrophysics Data System (ADS)

    Soni, Sanjeev Kant

    An important constraint on Grand Unified Theories (GUTs) is the correct estimate of Baryon Asymmetry of the Universe (BAU), in the standard scenario and with a conventional energy-temperature behavior. This is proportional to the intrinsic maximal CP-violation at superhigh energies, which as the lore goes barely accounts for the observed baryon -to-entropy ratio. This is further controlled by some global features: a global symmetry, if broken inadequately, can unduely suppress our estimate and the problem is how to overwhelm the suppression. Illustrated variously, this possibility of the group-theoretical constraint is also contrasted with that of a dynamical constraint. We focus our attention on a specific constraint, that arising from the broken group-C invariance (C = Charge-conjugation), note its implications on neutrino mass and examine, in particular, how to overwhelm the resulting suppression by splitting the mass of the decaying scalar X from its charge conjugate X('c) in an SO(10) theory with Witten's mechanism for neutrino mass. This possibility of X-X('c) mass-splitting was envisaged in our previous general study (with Haber and Segre) whose important conclusions are reviewed: some general observations on spontaneously unbroken C-invariance and a solution to the problem of BAU, in spontaneously broken C-invariant theories, by allowing no overlap between the contributions form the free-decays of X-X(' )and X('c) -X('c) pairs through (nu)-N('c) mass splitting >(, )10('10) GeV, or/and, when X X('c), through X-X('c) mass splitting >(, )m (X). Only the following details are now added. As examples of GUTs with uniquely defined C, we give the maximal and the minimal (single-family) unification schemes based on SU(16) and SO(10) respectively. We discuss in detail the X-X('c) mass splitting scenario with(' )X-X(X('c)-X('c)) belonging to the (6, 3, 1)(,+2) ((6, 1, 3)(,-2)) subcomponent of the 120 of SO(10). In addition to explicitizing the mass-splitting, we

  11. Spatiotemporal behavior of climatic characteristics determining evolution of forest ecosystems in Siberia in the second half of XX century

    NASA Astrophysics Data System (ADS)

    Shulgina, Tamara; Bogomolov, Vasily; Genina, Elena; Gordov, Evgeny

    2010-05-01

    It is well known that both global and regional climate changes influence biological processes occurring in different ecosystems. In particular, they determine forest productivity that plays important role in global carbon balance forming. The paper presents investigation results for climate indices dynamics that determine evolution of forest ecosystems in Siberia in the second half of XX century. The ECMWF data (spatial resolution of 0.5°×0.5°) and observations of the weather stations in Siberia over the period from 1974 to 2000 were taken as initial data. The paper presents calculation results for fields of the following climatic characteristics: duration of growing season and its mean temperature, sum of degree day temperature, precipitation amount and Selyaninov hydrothermal coefficient. Calculation results have shown an increase of growing season duration by 4-6 days in Siberia for all period under study (32 years). Mean air temperature dynamics in growing season has weak positive trend and inhomogeneous structure over all Siberian territory. Thus, maximum increase of mean temperature for growing season is observed in south taiga and is equal to 0.9° C per 32 years. Analysis of precipitation amount dynamics shows inhomogeneity in its change. Significant increase of precipitation amount is observed in temperate forests and steppe. As a results of increase of temperature and precipitation amount, Selyaninov hydrothermal coefficient significantly increases in the south of Siberia that suggests increase of water content in soil on the territory under study. However, to study forest ecosystem response to climate changes, we need climatic characteristics fields with higher spatial resolution. To do this, we used a WRF mesoscale model and calculated meteorological fields with spatial resolution of 10 km. These fields take into account influence of surface layer on climate forming and allow us to analyze in detail local response of forest ecosystems to regional

  12. Comparing sex steroid levels during the annual cycles of rainbow trout (Oncorhynchus mykiss) diploid female (XX) and triploid female (XXX) genotypic sex.

    PubMed

    Espinosa, E; Josa, A; Gil, L; Malo, C; Mitjana, O

    2013-02-01

    In this study, the annual cycle of the gonadal steroids testosterone (T), 11-ketotestosterone (11-KT), 17β-estradiol (E2) and 17α, 20β-dihydroxy-4-pregnen-3-one (DHP) was determined using radioimmunoassay and then compared for two populations of rainbow trout, XX diploid females (n = 40) and XXX triploid females (n = 15). In females, E2 and DHP levels were found to be significantly related to body weight (r = 0.22513; p < 0.0001 and r = 0.15831; p > 0.001, respectively). In this group, E2 concentrations peaked in November (25.05 ng/ml), while maximum DHP levels, only measurable from October to April, were attained in February (64.14 ng/ml). No significant differences in hormone ranges related to egg output ability were observed. Finally, sex steroid concentrations were low in the triploid female XXX fish compared to the female XX population. Nevertheless, maximum T (33.85 ng/ml) and 11-KT (32.35 ng/ml) levels were recorded in January, for XXX. The levels for these two hormones are relatively high and are also significantly associated (r = 0.8430; p < 0.0001). Diploid females showed significantly higher levels of E2 than triploids over the 12-month study period. The female triploid fish produced the lowest steroid hormone levels, such that these would be the most suitable for human consumption.

  13. A Euploid Line of Human Embryonic Stem Cells Derived from a 43,XX,dup(9q),+12,-14,-15,-18,-21 Embryo

    PubMed Central

    Fonseca, Simone Aparecida Siqueira; Costas, Roberta Montero; Morato-Marques, Mariana; Costa, Silvia; Alegretti, Jose Roberto; Rosenberg, Carla; da Motta, Eduardo Leme Alves; Serafini, Paulo C.; Pereira, Lygia V.

    2015-01-01

    Aneuploid embryos diagnosed by FISH-based preimplantation genetic screening (PGS) have been shown to yield euploid lines of human embryonic stem cells (hESCs) with a relatively high frequency. Given that the diagnostic procedure is usually based on the analysis of 1–2 blastomeres of 5 to 10-cell cleavage-stage embryos, mosaicism has been a likely explanation for the phenomena. However, FISH-based PGS can have a significant rate of misdiagnosis, and therefore some of those lines may have been derived from euploid embryos misdiagnosed as aneuploid. More recently, coupling of trophectoderm (TE) biopsy at the blastocyst stage and array-CGH lead to a more informative form of PGS. Here we describe the establishment of a new line of hESCs from an embryo with a 43,XX,dup(9q),+12,-14,-15,-18,-21 chromosomal content based on array-CGH of TE biopsy. We show that, despite the complex chromosomal abnormality, the corresponding hESC line BR-6 is euploid (46,XX). Single nucleotide polymorphism analysis showed that the embryo´s missing chromosomes were not duplicated in BR-6, suggesting the existence of extensive mosaicism in the TE lineage. PMID:26540511

  14. A trio of horseshoes: past, present and future dynamical evolution of Earth co-orbital asteroids 2015 XX169, 2015 YA and 2015 YQ1

    NASA Astrophysics Data System (ADS)

    de la Fuente Marcos, C.; de la Fuente Marcos, R.

    2016-04-01

    It is widely accepted that a quasi-steady-state flux of minor bodies moving in and out of the co-orbital state with the Earth may exist. Some of these objects are very good candidates for future in situ study due to their favourable dynamical properties. In this paper, we show that the recently discovered near-Earth asteroids 2015 XX_{169}, 2015 YA and 2015 YQ1 are small transient Earth co-orbitals. These new findings increase the tally of known Earth co-orbitals to 17. The three of them currently exhibit asymmetric horseshoe behaviour subjected to a Kozai resonance and their short-term orbital evolution is rather unstable. Both 2015 YA and 2015 YQ1 may leave Earth's co-orbital zone in the near future as they experience close encounters with Venus, the Earth-Moon system and Mars. Asteroid 2015 XX_{169} may have remained in the vicinity of, or trapped inside, the 1:1 mean motion resonance with our planet for many thousands of years and may continue in that region for a significant amount of time into the future.

  15. Propagation of the interaction generating the macroscopic entanglement in a XX spin-1/2 < 1/2 chain with a staggered magnetic field

    NASA Astrophysics Data System (ADS)

    Avila, M.

    2012-05-01

    An effective Poynting vector associated to a XX chain of a spin-1/2 < 1/2 with staggered magnetic field, Bl = B + e-iπlbis derived. Such a field is not likely to occur in nature although the model is analytically solvable and allows to study macroscopic correlation (entanglement witnessing) [J. Hide, W. Son, I. Lawrie, V. Vedral, Phys. Rev. A 76, 022319 (2007)]. It is found that the propagation of the interaction generating of the macroscopic correlations has a component which is not along to the axis of the chain. This questions the idea that the propagation of the macroscopic (multipartite) entanglement takes place exclusively along the axis of the chain of XX spin-1/2. < 1/2 We point out that in general, that the propagation of macroscopic entanglement is not an one-dimensional phenomenon but this occurs in a region of the space. Some reliable criteria for macroscopic correlation in terms of our effective Poynting's vector are derived. Associated with entanglement propagation, an effective group velocity by volume unit that satisfies a Lieb-Robinson-like upper bound for the velocity of the propagation of the information has been found.

  16. Electronic, magnetic and thermal properties of Co2CrxFe1-xX (X=Al, Si) Heusler alloys: First-principles calculations

    NASA Astrophysics Data System (ADS)

    Guezlane, M.; Baaziz, H.; El Haj Hassan, F.; Charifi, Z.; Djaballah, Y.

    2016-09-01

    Density functional theory (DFT) based on the full-potential linearized augmented plane wave (FP-LAPW) method is used to investigate the structural, electronic, magnetic and thermal properties of Co2CrxFe1-xX (X=Al, Si) full Heusler alloys, with L21 structure. The structural properties and spin magnetic moments are investigated by the generalized gradient approximations (GGA) minimizing the total energy. For band structure calculations, GGA, the Engel-Vosko generalized gradient approximation (EVGGA) and modified Becke-Johnson (mBJ) schemes are used. Results of density of states (DOS) and band structures show that these alloys are half-metallic ferromagnets (HMFS). A regular-solution model has been used to investigate the thermodynamic stability of the compounds Co2CrxFe1-xX that indicates a phase miscibility gap. The thermal effects using the quasi-harmonic Debye model are investigated within the lattice vibrations. The temperature and pressure effects on the heat capacities, Debye temperatures and entropy are determined from the non-equilibrium Gibbs functions.

  17. An XX/XY sex chromosome system in a fish species, Hoplias malabaricus, with a polymorphic NOR-bearing X chromosome.

    PubMed

    Born, G G; Bertollo, L A

    2000-01-01

    Cytogenetic studies were carried out in the fish, Hoplias malabaricus, from the Parque Florestal do Rio Doce (Brazil). This population is characterized by 2n = 42 chromosomes for both males and females and an XX/XY sex chromosome system, confirmed through several banding methods. Females show 24 metacentric, 16 submetacentric and 2 subtelocentric chromosomes. Males show 24 metacentric, 17 submetacentric and 1 subtelocentric chromosomes. While the X chromosome is easily recognized (the only subtelocentric element), the Y chromosome is somewhat difficult to identify but appears to correspond to the smallest submetacentric in the male karyotype. In-situ hybridization with an 18S rDNA probe showed 10 well-labeled chromosomes, including the X chromosome. The 5S rDNA is interstitially located in a single metacentric pair independent of the 18S rDNA sites. The NOR on the X chromosome is always active and occurs adjacent to a heterochromatic distal segment on the long arm. Variations in size of the NORs and/or heterochromatic segment correspond to a polymorphic size condition observed in the X chromosome. The present results confirm the XX/XY sex chromosome system in the population analyzed as well as a new cytotype in the Hoplias malabaricus group.

  18. Homozygosity for a Robertsonian Translocation (13q;14q) in a Phenotypically Normal 44, XX Female with a History of Recurrent Abortion and a Normal Pregnancy Outcome

    PubMed Central

    Miryounesi, Mohammad; Diantpour, Mehdi; Motevaseli, Elahe; Ghafouri-Fard, Soudeh

    2016-01-01

    Background: Robertsonian translocations are structural chromosomal abnormalities caused by fusion of two acrocentric chromosomes. In carriers of such translocations, different modes of segregations would result in the formation of either balanced (alternate segregation mode) or unbalanced (adjacent 1, adjacent 2, and 3:1 segregation modes) gametes. In addition, there is an increased risk for imprinting disorders in their offspring. Although it has been estimated that 1/1000 healthy persons carry a Robertsonian translocation, homozygosity for this type of structural chromosomal abnormality has been reported rarely. Most of reported cases are phenotypically normal but experience adverse pregnancy outcomes. Case Presentation: In this paper, a report was made on a normal female with a history of 4 consecutive first trimester fetal losses and a normal son referred to Center for Comprehensive Genetics Services, Tehran, Iran, in summer 2015. Cytogenetic analyses of proband and her infant showed 44, XX, der(13;14) (q10;q10)x2 and 45, XY, der(13;14)(q10;q10), respectively. Parents of proband have been shown to have 45, XY, der(13q;14q) and 45, XX, der(13q;14q) karyotypes, respectively. Conclusion: The present report was in agreement with the few reports of homozygosity for Robertsonian translocation which demonstrated normal phenotypes for such persons and possibility of giving birth to phenotypically normal heterozygote carriers of Robertsonian translocations. PMID:27478773

  19. Chromosome landmarks and autosome-sex chromosome translocations in Rumex hastatulus, a plant with XX/XY1Y2 sex chromosome system.

    PubMed

    Grabowska-Joachimiak, Aleksandra; Kula, Adam; Książczyk, Tomasz; Chojnicka, Joanna; Sliwinska, Elwira; Joachimiak, Andrzej J

    2015-06-01

    Rumex hastatulus is the North American endemic dioecious plant with heteromorphic sex chromosomes. It is differentiated into two chromosomal races: Texas (T) race characterised by a simple XX/XY sex chromosome system and North Carolina (NC) race with a polymorphic XX/XY1Y2 sex chromosome system. The gross karyotype morphology in NC race resembles the derived type, but chromosomal changes that occurred during its evolution are poorly understood. Our C-banding/DAPI and fluorescence in situ hybridization (FISH) experiments demonstrated that Y chromosomes of both races are enriched in DAPI-positive sequences and that the emergence of polymorphic sex chromosome system was accompanied by the break of ancestral Y chromosome and switch in the localization of 5S rDNA, from autosomes to sex chromosomes (X and Y2). Two contrasting domains were detected within North Carolina Y chromosomes: the older, highly heterochromatinised, inherited from the original Y chromosome and the younger, euchromatic, representing translocated autosomal material. The flow-cytometric DNA estimation showed ∼3.5 % genome downsizing in the North Carolina race. Our results are in contradiction to earlier reports on the lack of heterochromatin within Y chromosomes of this species and enable unambiguous identification of autosomes involved in the autosome-heterosome translocation, providing useful chromosome landmarks for further studies on the karyotype and sex chromosome differentiation in this species.

  20. Spot evolution on the red giant star XX Triangulum. A starspot-decay analysis based on time-series Doppler imaging

    NASA Astrophysics Data System (ADS)

    Künstler, A.; Carroll, T. A.; Strassmeier, K. G.

    2015-06-01

    Context. Solar spots appear to decay linearly proportional to their size. The decay rate of solar spots is directly related to magnetic diffusivity, which itself is a key quantity for the length of a magnetic-activity cycle. Is a linear spot decay also seen on other stars, and is this in agreement with the large range of solar and stellar activity cycle lengths? Aims: We investigate the evolution of starspots on the rapidly-rotating (Prot≈24 d) K0 giant XX Tri, using consecutive time-series Doppler images. Our aim is to obtain a well-sampled movie of the stellar surface over many years, and thereby detect and quantify a starspot decay law for further comparison with the Sun. Methods: We obtained continuous high-resolution and phase-resolved spectroscopy with the 1.2-m robotic STELLA telescope on Tenerife over six years, and these observations are ongoing. For each observing season, we obtained between 5 to 7 independent Doppler images, one per stellar rotation, making up a total of 36 maps. All images were reconstructed with our line-profile inversion code iMap. A wavelet analysis was implemented for denoising the line profiles. To quantify starspot area decay and growth, we match the observed images with simplified spot models based on a Monte Carlo approach. Results: It is shown that the surface of XX Tri is covered with large high-latitude and even polar spots and with occasional small equatorial spots. Just over the course of six years, we see a systematically changing spot distribution with various timescales and morphology, such as spot fragmentation and spot merging as well as spot decay and formation. An average linear decay of D = -0.022 ± 0.002 SH/day is inferred. We found evidence of an active longitude in phase toward the (unseen) companion star. Furthermore, we detect a weak solar-like differential rotation with a surface shear of α = 0.016 ± 0.003. From the decay rate, we determine a turbulent diffusivity of ηT = (6.3 ± 0.5) × 1014 cm2/s and

  1. Familial ring (18) mosaicism in a 23-year-old young adult with 46,XY,r(18) (::p11→q21::)/46,XY karyotype, intellectual disability, motor retardation and single maxillary incisor and in his phenotypically normal mother, karyotype 47,XX,+r(18)(::p11→q21::)/46,XX.

    PubMed

    Balci, Sevim; Tümer, Celal; Karaca, Ciğdem; Bartsch, Oliver

    2011-05-01

    We report on a 23-year-old man with craniofacial findings of the holoprosencephaly spectrum disorder (microcephaly, hypotelorism, depressed nasal bridge, single median maxillary central incisor), fusion of C2-C3 vertebrae, intellectual disability, and severe sleep apnea. Chromosome analysis of blood lymphocytes showed 75% ring (18) cells and 25% normal cells, karyotype mos 46,XY,r(18)(::p11→q21::)[75]/46,XY[25]. His mother was phenotypically normal except for a double ureter and bifid renal pelvis as in his son. She had a supernumerary ring (18) in 10% of blood lymphocytes, karyotype mos 47,XX,+r(18)(::p11→q21::)[10]/46,XX[90]. Familial ring (18) is a rare cytogenetic abnormality. This is the first report of a mother with a supernumerary ring (18) and a son with ring (18) mosaicism. Interestingly, the son showed a true mosaicism (mixoploidy) of ring (18) and normal cells. The mother's 46,XX cells could be easily explained by mitotic instability and ring loss during cell division. However, the coexistence of ring (18) and normal cells in the son is unusual. Possibly, during early postzygotic divisions of a 47,XY,+r(18) zygote, two (possibly subsequent) genetic events could have occurred, one when one normal chromosome 18 was lost (resulting in a cell line with ring 18), and one when the ring 18 was lost (resulting in a cell line without ring, "escape to normal"). Alternatively, the zygote of the son could have been 46,XY,r(18), and postzygotic loss of the ring 18 could have resulted in monosomy 18 cells followed by duplication of chromosome 18 in these cells (a rare mechanism for cell survival previously described as "compensatory" isodisomy).

  2. A glance at Spanish embryology and teratology during the XX century through the academic life of Francisco Orts-Llorca (1905-1993).

    PubMed

    Aréchaga, Juan; Jiménez-Collado, Juan; Ruano-Gil, Domingo

    2009-01-01

    Francisco Ort-Llorca (1905-1993) was one of the most outstanding Spanish embryologists of the XX century. He was disciple of Henri Rouvire in Paris (France), Alfred Fischel in Vienna (Austria), Walther Vogt in Munich (Germany) and Pedro Ara in Madrid (Spain). From 1935, he was professor of Human Anatomy at the Faculty of Medicine of Cadiz, belonged then to the University of Seville (accidentally, in the University of Valencia, during the Spanish Civil War from 1936-1939) and, later on, at the Faculty of Medicine of Madrid (Complutense University) from 1954 to 1975. He was internationally recognized in anatomical sciences and stood out for his contributions to descriptive and experimental Embryology and Teratology, particularly in those aspects connected to the normal and pathological development of the heart and visual organs.

  3. Gonadal dysgenesis and the Mayer-Rokitansky-Kuster-Hauser Syndrome in a girl with a 46, XX karyotype: A case report and review of literature.

    PubMed

    Kebaili, Sahbi; Chaabane, Kais; Mnif, Mouna Feki; Kamoun, Mahdi; Kacem, Faten Hadj; Guesmi, Nouha; Gassara, Hichem; Dammak, Abdallah; Louati, Doulira; Amouri, Habib; Guermazi, Mohamed

    2013-05-01

    Mayer-Rokitansky-Kuster-Hauser (MRKH) is a characteristic syndrome in which the Mullerian structures are absent or rudimentary. It is also associated with anomalies of the genitourinary and skeletal systems. Its association with gonadal dysgenesis is extremely rare and appears to be fortuitous, independent of chromosomal anomalies. We report such a case in a 21-year-old girl who presented primary amenorrhea and impuberism. The endocrine study revealed hypergonadotrophic hypogonadism. The karyotype was normal, 46, XX. No chromosome Y was detected at the fluorescence in situ hybridization (FISH) analysis. Internal genitalia could not be identified on the pelvic ultrasound and pelvic magnetic resonance imaging. Laparoscopy disclosed concomitant ovarian dysgenesis and MRKH syndrome. There were no other associated malformations. Hormonal substitution therapy with oral conjugated estrogens was begun. The patient has been under regular follow-up for the last two years and is doing well.

  4. Gonadal dysgenesis and the Mayer-Rokitansky-Kuster-Hauser Syndrome in a girl with a 46, XX karyotype: A case report and review of literature

    PubMed Central

    Kebaili, Sahbi; Chaabane, Kais; Mnif, Mouna Feki; Kamoun, Mahdi; Kacem, Faten Hadj; Guesmi, Nouha; Gassara, Hichem; Dammak, Abdallah; Louati, Doulira; Amouri, Habib; Guermazi, Mohamed

    2013-01-01

    Mayer-Rokitansky-Kuster-Hauser (MRKH) is a characteristic syndrome in which the Mullerian structures are absent or rudimentary. It is also associated with anomalies of the genitourinary and skeletal systems. Its association with gonadal dysgenesis is extremely rare and appears to be fortuitous, independent of chromosomal anomalies. We report such a case in a 21-year-old girl who presented primary amenorrhea and impuberism. The endocrine study revealed hypergonadotrophic hypogonadism. The karyotype was normal, 46, XX. No chromosome Y was detected at the fluorescence in situ hybridization (FISH) analysis. Internal genitalia could not be identified on the pelvic ultrasound and pelvic magnetic resonance imaging. Laparoscopy disclosed concomitant ovarian dysgenesis and MRKH syndrome. There were no other associated malformations. Hormonal substitution therapy with oral conjugated estrogens was begun. The patient has been under regular follow-up for the last two years and is doing well. PMID:23869310

  5. [The scientific revolution in medicine of the last quarter of XIX-first half of XX centuries. Report I. The causes and mechanisms of scientific revolution].

    PubMed

    Stochik, A M; Zatravkin, S N

    2015-01-01

    The article describes the system of conceptions about subject of investigation in medicine and methods of research activities of physicians well-established by early 70s of XIX century. It is postulated that in the middle of 1870s in medicine occurred an objective need of entirely different from before vision of investigated reality, development and implementation of fundamentally new methodological approaches to its studying that by-turn initiated global scientific revolution in medicine of the last quarter of XIX-first half of XX centuries. It is substantiated that need of new vision of investigated reality became first of all a consequence of profound intra-disciplinary crisis related to awareness of fallibility of existed ideas of human organism and its vital activity. The second cause is two "paradigm inoculations" from biology which resulted in forced acceptance by physicians the extreme incompleteness and fallacy of their previous views concerning environment and essence of its effect on human organism.

  6. A rare case of mosaic 45,X/47,XX,+13 in 28-year-old women with secondary amenorrhoea: A case report and literature review

    PubMed Central

    Kumar, Mohit; Lal, Vandana; Chapadgaonkar, Shilpa; Bhattacharya, Saurabh Kumar

    2014-01-01

    In the present paper we report an extremely rare case of mosaicism of 45,X/47,XX,+13 in a 28-year-old women. The patient was referred for cytogenetic evaluation for secondary amenorrhoea. The patient was found to have some mild characteristic features of Turner syndrome such as wide carrying angle and short stature. Ultrasound examination revealed the presence of a small sized uterus and bilateral streak ovaries. G-banded chromosome analysis revealed a mosaic female karyotype involving two different cell lines. One cell line (72% of analysed metaphases) presented monosomy of X while the remaining 28% of cells showed trisomy of chromosome 13. Fluorescence in situ hybridization (FISH) with locus specific probe for trisomy 13 and CEP X for monosomy X substantiated the results obtained from karyotyping. PMID:26925371

  7. A search for parent molecules at millimetre wavelengths in Comets Austin 1990 V and Levy 1990 XX - Upper limits for undetected species

    NASA Astrophysics Data System (ADS)

    Crovisier, J.; Bockelee-Morvan, D.; Colom, P.; Despois, D.; Paubert, G.

    1993-03-01

    The microwave spectra of Comets Austin 1990 V and Levy 1990 XX were observed with the IRAM 30-m radio telescope. As we have reported previously, the HCN, H2S, H2CO, and CH3OH molecules were detected. In addition, the lines of several other molecules of cometary interest were searched for without success, either during dedicated searches or serendipitously: H2O2, CH3CCH, HCOOH, C2H5OH, CH3OCH3, CH3COOH, HC3HO, HC3N, and many others. We report these searches in detail and evaluate the corresponding limits on the production rates. For several molecules, this limit is of the order of 0.001 relative to water, or less. The consequences for the nature of comets are discussed.

  8. A rare case of mosaic 45,X/47,XX,+13 in 28-year-old women with secondary amenorrhoea: A case report and literature review.

    PubMed

    Kumar, Mohit; Lal, Vandana; Chapadgaonkar, Shilpa; Bhattacharya, Saurabh Kumar

    2015-02-01

    In the present paper we report an extremely rare case of mosaicism of 45,X/47,XX,+13 in a 28-year-old women. The patient was referred for cytogenetic evaluation for secondary amenorrhoea. The patient was found to have some mild characteristic features of Turner syndrome such as wide carrying angle and short stature. Ultrasound examination revealed the presence of a small sized uterus and bilateral streak ovaries. G-banded chromosome analysis revealed a mosaic female karyotype involving two different cell lines. One cell line (72% of analysed metaphases) presented monosomy of X while the remaining 28% of cells showed trisomy of chromosome 13. Fluorescence in situ hybridization (FISH) with locus specific probe for trisomy 13 and CEP X for monosomy X substantiated the results obtained from karyotyping.

  9. Paracentric inversion of chromosome 7 (46,XX,inv(7)(q21.2q22)) in a newborn with hypoplastic left heart syndrome

    SciTech Connect

    Kuforjii, T.A.; Pillers, D.M.; Silberbach, M.

    1994-09-01

    Hypoplastic left heart syndrome (HLHS) is a severe congenital heart disease that is uniformly fatal without surgical intervention. Fetal echocardiography allows prenatal diagnosis, but this condition may not become apparent until after the mid-second trimester. We report a term baby with severe HLHS who had an 18 week fetal ultrasound that reportedly demonstrated a normal heart. There was no family history of congenital heart disease. She was phenotypically female with no dysmorphic features. Physical examination was otherwise normal. She expired at 48 hours of age. The autopsy was noncontributory. The karyotype was 46,XX, but there was an apparently balanced paracentric inversion of the long arm of chromosome 7 (46,XX,inv(7)(q21.2q22)). The mother`s chromosome study was normal without any inversion, and the father was not available for study. Hypoplastic left heart syndrome has been associated with extracardiac anomalies and chromosomal abnormalities including 45,XO,11q-, and trisomy 18. It has also been reported in 5 members spanning 3 generations of a family with a spectrum of left heart defects suggesting an autosomal dominant pattern with high penetrance. First-degree relatives of infants with HLHS have a thirteen percent incidence of related cardiovascular malformations, a frequency higher than predicted by a multifactorial model of inheritance, suggesting that at least a portion of HLHS have a genetic basis. Karyotype analysis, including high resolution banding, may help define the etiology of this condition. Chromosome 7 has not been implicated in HLHS. This case emphasizes the need for genetic analysis, including a pedigree, of affected families. It also underscores the importance of screening by karyotype analysis to determine whether defects of the long arm of chromosome 7 are important in the pathogenesis of hypoplastic left heart syndrome.

  10. Five new cases of 46,XX aromatase deficiency: clinical follow-up from birth to puberty, a novel mutation, and a founder effect.

    PubMed

    Marino, Roxana; Perez Garrido, Natalia; Costanzo, Mariana; Guercio, Gabriela; Juanes, Matías; Rocco, Carlos; Ramirez, Pablo; Warman, Diana M; Ciaccio, Marta; Pena, Gladys; Feyling, José García; Miras, Mirta; Rivarola, Marco A; Belgorosky, Alicia; Saraco, Nora

    2015-02-01

    Aromatase is the key enzyme for estrogen biosynthesis and is encoded by the CYP19A1 gene. Since 1991, several molecular CYP19A1 gene alterations associated with aromatase deficiency have been described in both sexes. The objective of the study was to detect CYP19A1 mutations in five aromatase-deficient 46,XX patients, to describe the clinical follow-up from birth to puberty and to perform haplotype analysis associated with the high-frequency c.628G>A splice mutation in Argentinean patients. The design of the study was the sequencing of the coding and flanking intronic regions of the CYP19A1 gene in all patients and parents. Haplotype analysis of patients carrying the c.628G>A mutation was also performed. Clinical and biochemical findings in five new cases and one previously reported female aromatase-deficient patient (46,XX) are described. All patients presented with ambiguous genitalia at birth. Congenital adrenal hyperplasia due to 21-hydroxylase deficiency as well as other steroidogenic defects were ruled out. Phenotypic variability among the affected patients was found during follow-up. Direct sequencing of the CYP19A1 gene from genomic DNA revealed one novel mutation (c.574C>T) in two patients. In silico analysis predicted the c.574C>T mutation to be probably damaging. Four of six nonrelated patients presented with the c.628G>A splice mutation. Haplotype analysis showed that the c.628G>A splice mutation is associated with the same haplotype in our population. Increased knowledge on phenotypical variability found in female aromatase-deficient patients is useful to improve the detection rate in this disorder. In our population, a genetic founder defect has probably contributed to an increase in the incidence of the c.628G>A splice mutation.

  11. Quality of life in a large cohort of adult Brazilian patients with 46,XX and 46,XY disorders of sex development from a single tertiary centre.

    PubMed

    Cassia Amaral, Rita; Inacio, Marlene; Brito, Vinicius N; Bachega, Tania A S S; Oliveira, Ari A; Domenice, Sorahia; Denes, Francisco T; Sircili, Maria Helena; Arnhold, Ivo J P; Madureira, Guiomar; Gomes, Larissa; Costa, Elaine M F; Mendonca, Berenice B

    2015-02-01

    Few studies have focused on the quality of life (QoL) of patients with disorders of sex development (DSD). Our aim was to evaluate QoL in DSD patients with defined diagnoses followed until adulthood in a single tertiary centre. Adult patients with DSD (56 patients with 46,XX DSD - 49 with female social sex and 7 with male social sex as well as 88 patients with 46,XY DSD - 54 with female social sex and 34 with male social sex). QoL using WHOQOL-Bref questionnaire. Both patients with 46,XX DSD and patients with 46,XY DSD had similar QoL scores on the WHOQOL-Bref, comparable to the scores of the Brazilian general population. The chronological age at the start of treatment was negatively and significantly associated with general QoL score. Patients with male social sex DSD had better scores on the psychological domain than patients with female social sex DSD, as found in the Brazilian general population. In addition, among the 46,XY DSD group, the male social sex patients had better QoL compared with the female social sex patients. There was a positive and significant correlation between sexual performance and general QoL, although it explained only 4% of the variability of the general QoL score. The most influencing variables were general health, positive feelings and spirituality, religion and personal beliefs, each of them contributing with 18% of the variability of the general QoL score. Our large cohort of adult patients with DSD, which was followed by a multidisciplinary team in a single tertiary centre, had good QoL in adulthood; in addition, late treatment compromised the QoL of patients with DSD, whereas sexual performance has little influence on QoL. © 2014 John Wiley & Sons Ltd.

  12. [Drugs in artistic works of Stanislaw Ignacy Witkiewicz (1885-1939) on the Background of polish modernism at the turn of XIX and XX century].

    PubMed

    Płonka-Syroka, B

    1997-01-01

    At the turn of XIX and XX century in the Polish artistic circles it became widespread a modernist moral model, created among other by Baudelair's, Mallarme's Rimbaud's and Verlain's works. One of its elements was striving for getting into different status of conscience with help of narcotics and alcohol. A strong presence of narcotics in life of the Polish artistic circles at a time of mocernism has been a subject to analysis carried out by Tadeusz Boy-Zeleénski in his work "Cyganeria krakowska" [Crakow Bohemians]. He has shown their role of easing emotional tensions connected with striving for fame and with a competition. Underestimation, misery and social alienation of some artists have been inducing them to search in narcotics the way to artificial reality. In some Polish artistic circles the narcotics have become a stimulant of cult character (see Antoni Lange "Ballady pijackie", Stanisław Przybyszewski "Synowie ziemi", "Moi współcześni", Henryk Sienkiewicz "Bez dogmatu"). Stanisław Ignacy Witkiewicz (1885-1939), Polish painter and dramatist, creating in the first half of XX century, has continued a tradition of modernist customs, taken over by him from the artistic circle he was brought up. He used narcotics as direct creative stimulus, inspiring creation of his paintings, including a superb series of portraits. In paintings made under influence of the drugs, Witkiewicz was placing the symbols of stimulants taken earlier. He has specially appreciated cocaine, though he has been using also opium, morphine, hashish and mixes of various psychotropic agents. Paintings of Witkacy are characterised by original colouring of a very strong artistic expression. ...

  13. A Non-Reciprocal Autosomal Translocation 64,XX, t(4;10)(q21;p15) in an Arabian Mare with Repeated Early Embryonic Loss.

    PubMed

    Ghosh, S; Das, P J; Avila, F; Thwaits, B K; Chowdhary, B P; Raudsepp, T

    2016-02-01

    Balanced autosomal translocations are a known cause for repeated early embryonic loss (REEL) in horses. In most cases, carriers of such translocations are phenotypically normal, but the chromosomal aberration negatively affects gametogenesis giving rise to both genetically balanced and unbalanced gametes. The latter, if involved in fertilization, result in REEL, whereas gametes with the balanced form of translocation will pass the defect into next generation. Therefore, in order to reduce the incidence of REEL, identification of translocation carriers is critical. Here, we report about a phenotypically normal 3-year-old Arabian mare that had repeated resorption of conceptuses prior to day 45 of gestation and was diagnosed with REEL. Conventional and molecular cytogenetic analyses revealed that the mare had normal chromosome number 64,XX but carried a non-mosaic and non-reciprocal autosomal translocation t(4;10)(q21;p15). This is a novel translocation described in horses with REEL and the first such report in Arabians. Previous cases of REEL due to autosomal translocations have exclusively involved Thoroughbreds. The findings underscore the importance of routine cytogenetic screening of breeding animals.

  14. Equine disorders of sexual development in 17 mares including XX, SRY-negative, XY, SRY-negative and XY, SRY-positive genotypes.

    PubMed

    Villagómez, D A F; Lear, T L; Chenier, T; Lee, S; McGee, R B; Cahill, J; Foster, R A; Reyes, E; St John, E; King, W A

    2011-01-01

    We described the clinical, cytogenetic and molecular findings of 17 clinical equine cases presented for abnormal sexual development and infertility. Six horses with an enlarged clitoris had an XX, SRY-negative genotype, which displayed male-like behavior (adult individuals). Bilateral ovotestes were noted in 2 of those cases, while another case showed increased levels of circulating testosterone. Six horses with a female phenotype, including normal external genitalia, had an XY, SRY-negative genotype. These individuals had small gonads and an underdeveloped internal reproductive tract. Four horses with normal appearing external genitalia had an XY, SRY-positive genotype, 3 of them had hypoplastic testes and male-like behavior. In addition, one young filly with enlarged clitoris and hypoplastic testes had the same genotype but did not show male-like behavior due to her age. Three of these horses were related with 2 being siblings. These findings demonstrate the diversity of disorders of sexual development seen in the horse. Furthermore, they emphasize the need for further research to identify genes involved in abnormal sex determination and differentiation in the horse.

  15. Karyotypic analysis and FISH mapping of microsatellite motifs reveal highly differentiated XX/XY sex chromosomes in the pink-tailed worm-lizard (Aprasia parapulchella, Pygopodidae, Squamata)

    PubMed Central

    2013-01-01

    Background The infraorder Gekkota is intriguing because it contains multiple chromosomal and environmental sex determination systems that vary even among closely related taxa. Here, we compare male and females karyotypes of the pink-tailed worm-lizard (Aprasia parapulchella), a small legless lizard belonging to the endemic Australian family Pygopodidae. Results We applied comparative genomic hybridization to reveal an XX/XY sex chromosome system in which the Y chromosome is highly differentiated from the X in both gross morphology and DNA sequence. In addition, FISH mapping has revealed that two microsatellite repeat motifs, (AGAT)n and (AC)n, have been amplified multiple times on the Y chromosome. Conclusion XY karyotypes are found in other pygopodids (Delma inornata and Lialis burtonis), suggesting that the common ancestor of Pygopodidae also had XY sex chromosomes. However, the morphology and size of the Y chromosomes are different among the three species, suggesting that the processes underlying the evolution of sex chromosomes in the Pygopodidae involved chromosome rearrangements and accumulation and amplification of repeats. PMID:24344753

  16. An XX/XY heteromorphic sex chromosome system in the Australian chelid turtle Emydura macquarii: a new piece in the puzzle of sex chromosome evolution in turtles.

    PubMed

    Martinez, Pedro Alonzo; Ezaz, Tariq; Valenzuela, Nicole; Georges, Arthur; Marshall Graves, Jennifer A

    2008-01-01

    Chromosomal sex determination is the prevalent system found in animals but is rare among turtles. In fact, heteromorphic sex chromosomes are known in only seven of the turtles possessing genotypic sex determination (GSD), two of which correspond to cryptic sex microchromosomes detectable only with high-resolution cytogenetic techniques. Sex chromosomes were undetected in previous studies of Emydura macquarii, a GSD side-necked turtle. Using comparative genomic hybridization (CGH) and GTG-banding, a heteromorphic XX/XY sex chromosome system was detected in E. macquarii. The Y chromosome appears submetacentric and somewhat larger than the metacentric X, the first such report for turtles. CGH revealed a male-specific chromosomal region, which appeared heteromorphic using GTG-banding, and was restricted to the telomeric region of the p arm. Based on our observations and the current phylogeny of chelid turtles, we hypothesize that the sex chromosomes of E. macquarii might be the result of a translocation of an ancestral Y microchromosome as found in a turtle belonging to a sister clade, Chelodina longicollis, onto the tip of an autosome. However, in the absence of data from an outgroup, the opposite (fission of a large XY into an autosome and a micro-XY) is theoretically equally likely. Alternatively, the sex chromosome systems of E. macquarii and C. longicollis may have evolved independently. We discuss the potential causes and consequences of such putative chromosome rearrangements in the evolution of sex chromosomes and sex-determining systems of turtles in general.

  17. Extended calculations of level and transition properties in the nitrogen isoelectronic sequence: Cr XVIII, Fe XX, Ni XXII, and Zn XXIV

    NASA Astrophysics Data System (ADS)

    Radžiūtė, L.; Ekman, J.; Jönsson, P.; Gaigalas, G.

    2015-10-01

    Extensive multiconfiguration Dirac-Hartree-Fock (MCDHF) calculations and relativistic configuration interaction (RCI) calculations are performed for 272 states of the 2s22p3, 2s2p4, 2p5, 2s22p23l, 2s2p33l, and 2p43l (l = 0,1,2) configurations in the nitrogen-like ions Cr XVIII, Fe XX, Ni XXII, and Zn XXIV. Valence, core-valence, and core-core electron correlation effects are accounted for through large configuration state function expansions. Calculated energy levels are compared with data from other calculations and with experimental data from the NIST database. Landé gJ-factors; hyperfine structures; isotope shifts; and radiative electric dipole (E1), electric quadrupole (E2), and magnetic dipole (M1) transition rates are given for all ions. The accuracy of the calculated energy levels is high enough to facilitate identification of observed spectral lines involving the 2l43l' configurations, for which experimental data are largely missing. Tables 5-21 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/582/A61

  18. New Intermetallic Ternary Phosphide Chalcogenide AP2-xXx (A = Zr, Hf; X = S, Se) Superconductors with PbFCl-Type Crystal Structure

    NASA Astrophysics Data System (ADS)

    Kitô, Hijiri; Yanagi, Yousuke; Ishida, Shigeyuki; Oka, Kunihiko; Gotoh, Yoshito; Fujihisa, Hiroshi; Yoshida, Yoshiyuki; Iyo, Akira; Eisaki, Hiroshi

    2014-07-01

    We have synthesized a series of intermetallic ternary phosphide chalcogenide superconductors, AP2-xXx (A = Zr, Hf; X = S, Se), using the high-pressure synthesis technique. These materials have a PbFCl-type crystal structure (space group P4/nmm) when x is greater than 0.3. The superconducting transition temperature Tc changes systematically with x, yielding dome-like phase diagrams. The maximum Tc is achieved at approximately x = 0.7, at which point the Tc is 6.3 K for ZrP2-xSex (x = 0.75), 5.5 K for HfP2-xSex (x = 0.7), 5.0 K for ZrP2-xSx (x = 0.675), and 4.6 K for Hfp2-xSx (x = 0.5). They are typical type-II superconductors and the upper and lower critical fields are estimated to be 2.92 T at 0 K and 0.021 T at 2 K for ZrP2-xSex (x = 0.75), respectively.

  19. An assessment of Fe xx-Fe xxii emission lines in SDO/EVE data as diagnostics for high-density solar flare plasmas using EUVE stellar observations

    NASA Astrophysics Data System (ADS)

    Keenan, F. P.; Milligan, R. O.; Mathioudakis, M.; Christian, D. J.

    2017-06-01

    The Extreme Ultraviolet Variability Experiment (EVE) on the Solar Dynamics Observatory obtains extreme-ultraviolet (EUV) spectra of the full-disc Sun at a spectral resolution of ˜1 Å and cadence of 10 s. Such a spectral resolution would normally be considered to be too low for the reliable determination of electron density (Ne) sensitive emission line intensity ratios, due to blending. However, previous work has shown that a limited number of Fe xxi features in the 90-160 Å wavelength region of EVE do provide useful Ne-diagnostics at relatively low flare densities (Ne ≃ 1011-1012 cm-3). Here, we investigate if additional highly ionized Fe line ratios in the EVE 90-160 Å range may be reliably employed as Ne-diagnostics. In particular, the potential for such diagnostics to provide density estimates for high Ne (˜1013 cm-3) flare plasmas is assessed. Our study employs EVE spectra for X-class flares, combined with observations of highly active late-type stars from the EUVE satellite plus experimental data for well-diagnosed tokamak plasmas, both of which are similar in wavelength coverage and spectral resolution to those from EVE. Several ratios are identified in EVE data, which yield consistent values of electron density, including Fe xx 113.35/121.85 and Fe xxii 114.41/135.79, with confidence in their reliability as Ne-diagnostics provided by the EUVE and tokamak results. These ratios also allow the determination of density in solar flare plasmas up to values of ˜1013 cm-3.

  20. Projective line over the finite quotient ring GF(2)[x]/ 3 ™ x> and quantum entanglement: The Mermin ``magic'' square/pentagram

    NASA Astrophysics Data System (ADS)

    Saniga, M.; Planat, M.; Minarovjech, M.

    2007-05-01

    In 1993, Mermin gave surprisingly simple proofs of the Bell-Kochen-Specker (BKS) theorem in Hilbert spaces of dimensions four and eight respectively using what has since been called the Mermin-Peres “magic” square and the Mermin pentagram. The former is a 3×3 array of nine observables commuting pairwise in each row and column and arranged such that their product properties contradict those of the assigned eigenvalues. The latter is a set of ten observables arranged in five groups of four lying along five edges of the pentagram and characterized by a similar contradiction. We establish a one-to-one correspondence between the operators of the Mermin-Peres square and the points of the projective line over the product ring GF(2) ⊗ GF(2). Under this map, the concept mutually commuting transforms into mutually distant, and the distinguishing character of the third column’s observables has its counterpart in the distinguished properties of the coordinates of the corresponding points, whose entries are either both zero divisors or both units. The ten operators of the Mermin pentagram correspond to a specific subset of points of the line over GF(2)[x]/3 ™ x>. But the situation in this case is more intricate because there are two different configurations that seem to serve our purpose equally well. The first one comprises the three distinguished points of the (sub)line over GF(2), their three “Jacobson” counterparts, and the four points whose both coordinates are zero divisors. The other con.guration features the neighborhood of the point (1, 0) (or, equivalently, that of (0, 1)). We also mention some other ring lines that might be relevant to BKS proofs in higher dimensions.

  1. AB INITIO STUDY OF STRUCTURAL, ELECTRONIC AND OPTICAL PROPERTIES OF MgxCd1-xX (X = S, Se, Te) ALLOYS

    NASA Astrophysics Data System (ADS)

    Noor, N. A.; Shaukat, A.

    2012-12-01

    This study describes structural, electronic and optical properties of MgxCd1-xX (X = S, Se, Te) alloys in the complete range 0≤x ≤1 of composition x in the zinc-blende (ZB) phase with the help of full-potential linearized augmented plane wave plus local orbitals (FP-LAPW+lo) method within density functional theory (DFT). In order to calculate total energy, generalized gradient approximation (Wu-Cohen GGA) has been applied, which is based on optimization energy. For electronic structure calculations, the corresponding potential is being optimized by Engel-Vosko GGA formalism. Our calculations reveal the nonlinear variation of lattice constant and bulk modulus with different concentration for the end binary and their ternary alloys, which slightly deviates from Vegard's law. The calculated band structures show a direct band gap for all three alloys with increasing order in the complete range of the compositional parameter x. In addition, we have discussed the disorder parameter (gap bowing) and concluded that the total band gap bowing is substantially influenced by the chemical (electronegativity) contribution. The calculated density of states (DOS) of these alloys is discussed in terms of contribution from various s-, p- and d-states of the constituent atoms and charge density distributions plots are analyzed. Optical properties have been presented in the form of the complex dielectric function ɛ(ω), refractive index n(ω) and extinction coefficient k(ω) as function of the incident photon energy, and the results have been compared with existing experimental data and other theoretical calculations.

  2. A dispermic chimera was identified in a healthy man with mixed field agglutination reaction in ABO blood grouping and mosaic 46, XY/46, XX karyotype.

    PubMed

    Hong, Xiaozhen; Ying, Yanlin; Xu, Xianguo; Liu, Ying; Chen, Zhimei; Lan, Xiaofei; Ma, Kairong; He, Ji; Zhu, Faming; Lv, Hangjun; Yan, Lixing

    2013-04-01

    Chimerism is the presence of two or more genetically distinct cell populations in one organism. Here, we reported the identification of dispermic chimerism in a 25-year-old male. Blood grouping was performed with standard gel centrifugation test cards. ABO and HLA-A,-B,-C,-DRB1 and -DQB1 loci genotyping was determined with PCR sequence-based typing. A quantitative analysis of dual red cells populations was measured by flow cytometer. The karyotype was analyzed by G-banded chromosomes. Short tandem repeat (STR) analysis was performed on blood, buccal mucosal and hair shafts samples. A mixed-field agglutination with anti-B antibody was observed with gel centrifugation tests, which showed a double populations of O and B groups RBCs. Two groups RBCs were also observed by flow cytometer with nearly 90% O group cells and 10% B group cells. The normal O01,O02,B101 alleles were identified in DNA sample of the proband. STR analysis revealed three alleles for D8S1179,D3S1358,TH01,D13S317,D16S539,D2S1338,D19S433,TPOX and D18S51 loci. HLA-DRB1 and -DQB1 loci had three alleles and a karyotypic mosaic was found with 60% 46, XY and 40% 46, XX karyotype in the proband. In all studies, the third allele was attributable to a dual paternal contribution. A individual with dispermic chimerism was identified, which would generate by fertilization of an oocyte and the corresponding second polar body by two different sperms. Copyright © 2012 Elsevier Ltd. All rights reserved.

  3. Costs of landslides and floods in XX Century in a Calabrian town starting from the data stored in the Historical Archive of IRPI (Cosenza)

    NASA Astrophysics Data System (ADS)

    Giampa', Vincenzo; Pasqua, A. Aurora; Petrucci, Olga

    2015-04-01

    The paper firstly presents the historical archive of Cosenza IRPI Section and the historical database that has been built basing on the data contained in it. Then, an application of these data to Catanzaro, the town that is the administrative center of Calabria region (Southern Italy), is presented. The gathering of historical data on past floods and landslides in Cosenza IRPI Section has been started since 1996, and it is still in progress. In 2005, some donations coming from regional and municipal Public Works offices greatly increased the documental corpus, and required a more incisive classification and management that led us to organize the documents in a real historical archive. Documents were sorted according to municipalities they concerned. In this way, for each of the 409 municipalities of Calabria a set of documents, maps and images was available. Collected documents mainly concern damage caused by the occurrence, since XIX century, of phenomena as floods, flash floods and landslides triggered by extreme meteorological events, or even damage caused by strong earthquakes. At the beginning of 2014, the central office of IRPI (Perugia) funded a project aiming to the digitalization of the archive and the subsequent publication of it on a web-platform. In this paper, the procedure adopted to build the archive and implement the database is described. Then, the elaboration of the historical series of data on Catanzaro town, which has been frequently damaged by rainfall-induced landslides and floods, is also presented. Basing on the documents coming from the archive of Ministry Public Works and stored in our Historical Archive, an assessment of costs related to damage that during XX century affected the houses of this town has been performed. The research pointed out the types of most damaging phenomena, the municipal sectors most frequently damaged, and the evolution of damaged areas throughout the years according to the increasing urbanization.

  4. Time-resolved photometry of the nova remnants DM Gem, CP Lac, GI Mon, V400 Per, CT Ser and XX Tau

    NASA Astrophysics Data System (ADS)

    Rodríguez-Gil, P.; Torres, M. A. P.

    2005-02-01

    We present the first results of a photometric survey of poorly studied nova remnants in the Northern Hemisphere. The main results are as follows: DM Gem shows a modulation at 0.123 d (probably linked to the orbit) and rapid variations at ˜ 22 min. A moderate resolution spectrum taken at the time of the photometric observations shows intense He II 4686 and Bowen emission, characteristic of an intermediate polar or a SW Sex star. Variability at 0.127 d and intense flickering (or quasi-periodic oscillations) are the main features of the light curve of CP Lac. A 0.1-mag dip lasting for ˜ 45 min is observed in GI Mon, which could be an eclipse. A clear modulation (probably related to the orbital motion) either at 0.179 d or 0.152 d is observed in the B-band light curve of V400 Per. The results for CT Ser point to an orbital period close to 0.16 d. Intense flickering is also characteristic of this old nova. Finally, XX Tau shows a possible periodic signal near 0.14 d and displays fast variability at ˜ 24 min. Its brightness seems to be modulated at ˜ 5 d. We relate this long periodicity to the motion of an eccentric/tilted accretion disc in the binary. Based in part on observations made with the Jacobus Kapteyn Telescope, which was operated on the island of La Palma by the Isaac Newton Group in the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofísica de Canarias (IAC), and on observations made with the IAC80 telescope, operated on the island of Tenerife by the IAC in the Spanish Observatorio del Teide of the IAC. Observations were also obtained at the FLWO Observatory, a facility of the Smithsonian Institution.

  5. Clinical features and mental development of a child with a prenatally identified 45,XX,der(5)t(5;18) (p15;q11.2),-18 karyotype.

    PubMed Central

    Hutcheon, R G; Mallik, A; Shaham, M

    1998-01-01

    We present the clinical features and growth and development of a child with a 45,XX,der(5)t(5;18) (p15;q11.2),-18 karyotype. She had microcephaly, prominent, posteriorly rotated ears, short palpebral fissures with an upward slant, a wide nasal bridge, a thin upper lip, and a short neck. In addition, she had complex congenital heart disease. Although there has been delay in growth and development, she has shown progress in both areas. Images PMID:9783715

  6. Certification of new Pb iCRM (Candidate ERM-38xx series) via Gravimetric Isotope Mixtures and MC-ICP-MS Measurements

    NASA Astrophysics Data System (ADS)

    Ponzevera, E.; Quetel, C. R.

    2008-12-01

    Lead is known to be a particularly toxic chemical element. Mining and smelting of Pb and its domestic use over the centuries have contaminated the surface of Earth and jeopardized the health of humans, domestic animals and wildlife. Omnipresence of Pb has however an advantage. It can be used as an isotopic tracer of pollution sources and pathways in the environment. Pb isotopic Certified Reference Materials (iCRM) with undisputed characteristics are then required to validate Pb isotope ratio measurements. The materials currently available worldwide were produced in the 1960's by the National Bureau of Standards (now NIST, USA) and are now the object of polemics regarding the accuracy of some of the accompanying certified values. Moreover, new materials with lower relative uncertainty statements are demanded by users. This presentation is centred on the production and the certification at the EC-JRC-Institute for Reference Materials and Measurements of a new series of Pb iCRM (candidate ERM-38xx series). The production included six Pb gravimetric isotope mixtures, a common Pb material dedicated to routine calibration work and a series of four 207Pb slightly enriched natural-like Pb materials for the validation of the δ-scale method below 0.01%. The gravimetric isotope mixtures method, originally supported by mass spectrometry measurements performed on GS-MS or TI-MS instruments, was applied successfully to MC-ICP-MS. The measurements and certification methods we developed were validated in several ways, including a systematic investigation on possible significant sources of uncertainty and comparisons of results obtained by different laboratories on identical samples. Relative uncertainties on isotope ratios obtained for the newly produced Pb iCRM are as low as 0.017%, which is between 2 and 4 times smaller than the uncertainties carried by the NIST-981 material. Going below 0.01% was not possible mainly because of uncompressible uncertainties coming from the

  7. High-throughput sequencing analyses of XX genital ridges lacking FOXL2 reveal DMRT1 up-regulation before SOX9 expression during the sex-reversal process in goats.

    PubMed

    Elzaiat, Maëva; Jouneau, Luc; Thépot, Dominique; Klopp, Christophe; Allais-Bonnet, Aurélie; Cabau, Cédric; André, Marjolaine; Chaffaux, Stéphane; Cribiu, Edmond-Paul; Pailhoux, Eric; Pannetier, Maëlle

    2014-12-01

    FOXL2 loss of function in goats leads to the early transdifferentiation of ovaries into testes, then to the full sex reversal of XX homozygous mutants. By contrast, Foxl2 loss of function in mice induces an arrest of follicle formation after birth, followed by complete female sterility. In order to understand the molecular role of FOXL2 during ovarian differentiation in the goat species, putative FOXL2 target genes were determined at the earliest stage of gonadal sex-specific differentiation by comparing the mRNA profiles of XX gonads expressing the FOXL2 protein or not. Of these 163 deregulated genes, around two-thirds corresponded to testicular genes that were up-regulated when FOXL2 was absent, and only 19 represented female-associated genes, down-regulated in the absence of FOXL2. FOXL2 should therefore be viewed as an antitestis gene rather than as a female-promoting gene. In particular, the key testis-determining gene DMRT1 was found to be up-regulated ahead of SOX9, thus suggesting in goats that SOX9 primary up-regulation may require DMRT1. Overall, our results equated to FOXL2 being an antitestis gene, allowing us to propose an alternative model for the sex-determination process in goats that differs slightly from that demonstrated in mice. © 2014 by the Society for the Study of Reproduction, Inc.

  8. Genomic profile of a Li-Fraumeni-like syndrome patient with a 45,X/46,XX karyotype, presenting neither mutations in TP53 nor clinical stigmata of Turner syndrome.

    PubMed

    Basso, Tatiane R; Villacis, Rolando A R; Canto, Luisa M; Alves, Vinicius M F; Lapa, Rainer M L; Nóbrega, Amanda F; Achatz, Maria I; Rogatto, Silvia R

    2015-06-01

    Li-Fraumeni syndrome (LFS) is a hereditary disorder that predisposes patients to several types of cancer and is associated with TP53 germline mutations. Turner syndrome (TS) is one of the most common aneuploidies in women. Patients with TS have a higher risk of developing cancer, although multiple malignant tumors are extremely rare. Herein, we describe a patient with a 45,X/46,XX karyotype with no classic phenotype of TS. She presented with a clinical diagnosis of Li-Fraumeni-like syndrome (LFL), showing papillary thyroid carcinoma and fibrosarcoma of the left flank, and had no TP53 germline mutations. Genome-wide analysis of copy number variations (CNVs) was assessed in DNA from peripheral blood cells and saliva. A total of 109 rare CNVs in the blood cells, including mosaic loss of the X chromosome (76% of cells), were identified. In saliva, three rare CNVs were detected, all of them were also detected in the blood cells: loss of 8q24.11 (EXT1), gain of 16q24.3 (PRDM7 and GAS8), and the mosaic loss of the X chromosome (50% of cells). Results of conventional G-banding confirmed the 45,X/46,XX karyotype. Surprisingly, the patient presented with an apparently normal phenotype. The PRDM and GAS8 genes are potential candidates to be associated with the risk of developing cancer in this LFL/TS patient.

  9. Asplenia syndrome in a child with a balanced reciprocal translocation of chromosomes 11 and 20 [46,XX,t(11;20)(q13.1;q13.13)

    SciTech Connect

    Freeman, S.B.; May, K.M.; Blackston, R.D.; Muralidharan, K.

    1996-02-02

    We present a 6-year-old girl with a balanced 11;20 translocation [46,XX,t(11;20)(q13.1;q13.13)pat], asplenia, pulmonic stenosis, Hirschsprung disease, minor anomalies, and mental retardation. This case represents the second report of an individual with situs abnormalities and a balanced chromosome rearrangement involving a breakpoint at 11q13. Segregation analysis of markers in the 11q13 region in the proposita and her phenotypically normal carrier sibs did not show a unique combination of maternal and paternal alleles in the patient. We discuss several possible explanations for the simultaneous occurrence of situs abnormalities and a balanced 11;20 translocation. These include (1) chance, (2) a further chromosome rearrangement in the patient, (3) gene disruption and random situs determination, and (4) gene disruption plus transmission of a recessive or imprinted allele from the mother. 30 refs., 1 fig., 2 tabs.

  10. Extremely low losses 14xx single mode laser diode leading to 550-mW output power module with 0-75°C case temperature and 10-W consumption

    NASA Astrophysics Data System (ADS)

    Burie, J.-R.; Garabedian, P.; Starck, C.; Pagnod-Rossiaux, P.; Bettiati, M.; Do Nascimento, M.; Reygrobellet, J.-N.; Bertreux, J.-C.; Laruelle, F.

    2012-03-01

    High power 14xx laser pumps are more and more required for eye safe industrial, medical, safety and defense applications as well as for increased telecom network capability (e.g. for 100 Gb Ethernet). However, this need of high power requires to control the overall power consumption in a range in line with systems requirements. In this respect, 3S PHOTONICS has developed a 14xx nm single mode laser diode with record internal losses of 1.5 cm-1 compared to the 2.7 cm-1 reported up to now. These lasers are based on p/nBH technology and use the asymmetric waveguide concept to reduce internal losses. The record loss value, coupled to an internal efficiency higher than 0.8, allows realization lasers of 3 mm length with external efficiency higher than 0.5 W.A-1 at 25°C in AR/HR coating configuration. Modules using direct coupling technology were realized. High coupling efficiency is obtained thanks to the 8° x 14° far field pattern of the diode. Output power of 550 mW at 1.8 A is thus obtained, with or without FBG stabilization, with maximum output power above 700mW. Thanks to the lasers' length, voltage at this current level is below 1.9 V, which gives a reduced thermal load. Thus, the overall modules electrical consumption remains lower than 10 W at case temperatures ranging from 0°C to 75°C. The 3 mm length also guaranties high reliability of these laser diodes.

  11. Asplenia syndrome in a child with a reciprocal translocation of chromosomes 11 and 20 [46,XX,t(11;20)(q13.1;q13.13)

    SciTech Connect

    Freeman, S.B.; Muraldharan, K.; Pettay, D.

    1994-09-01

    Failure to establish the left-right embryonic axis results in abnormalities of laterality; situs solitus is replaced by situs inversus totalis or various degrees of heterotaxy involving the heart, great vessels, lungs, liver, spleen, and/or bowel. Laterality syndromes are likely to be genetically heterogeneous although specific human genes have not been identified. Families with dominant, recessive, and X-linked laterality syndromes have been reported as well as individuals with situs abnormalities and chromosome rearrangements. The latter offer the possibility of narrowing the gene search to specific chromosome regions. A recent report described an infant with polysplenia syndrome and a paracentric inversion of chromosome 11 [46,XX,inv(11)(q13q25)pat]. We report the second case of a child with laterality abnormalities and a chromosome rearrangement involving a similar breakpoint on chromosome 11. The proband is a 6 y/o female with mental retardation, dysmorphic features, pulmonic stenosis, asplenia, Hirschsprung disease, and a balanced, reciprocal translocation involving chromosomes 11 and 20 [46,XX,t(11;20)(q13,1;q13.13)pat]. Using DNA probes we have excluded uniparental disomy for chromosomes 11 and 20. If a gene for determination of laterality lies in the 11q13 region, the proband`s abnormalities could be the result of her receiving an allele disrupted by the paternal translocation as well as a mutant allele from her mother. To investigate this possibility, we are studying the segregation of maternal chromosome 11 markers in the proband and her balanced carrier and non-carrier siblings.

  12. Occurrence of multiple sexual chromosomes (XX/XY1Y2 and Z1Z1Z2Z2/Z1Z2W1W2) in catfishes of the genus Ancistrus (Siluriformes: Loricariidae) from the Amazon basin.

    PubMed

    de Oliveira, Renildo Ribeiro; Feldberg, Eliana; dos Anjos, Maeda Batista; Zuanon, Jansen

    2008-10-01

    Loricariid catfishes show a predominance of homomorphism in sex chromosomes, but cases of simple and multiple systems were also found. Here we describe two cases of multiple sex chromosome systems in loricariids from Brazilian Amazonia. Males of Ancistrus sp.1 "Balbina" have a modal number of 2n = 39 chromosomes, fundamental number (FN) of 78, and karyotypic formula of 27 m + 10 sm + 2 st; females have 2n = 38 chromosomes, FN = 76, and 26 m + 10 sm + 2 st. Ancistrus sp.2 "Barcelos" has 2n = 52 chromosomes for both sexes, FN = 80 for males and FN = 79 for females. Karyotypic formula is 12 m + 12 sm + 4 st + 24a for males and 11 m + 12 sm + 4st + 25a for females. The two species show different arrangements of constitutive heterochromatin blocks, which are coincident with NORs and absent in sex chromosomes. We suggest a XX/XY(1)Y(2) mechanism for Ancistrus sp.1 "Balbina", and a Z(1)Z(1)Z(2)Z(2)/Z(1)Z(2)W(1)W(2) mechanism for Ancistrus sp.2 "Barcelos". The XX/XY(1)Y(2) mechanism here reported is the second known occurrence of this type of multiple sex chromosomes for Loricariidae and the third for Neotropical fishes; the mechanism Z(1)Z(1)Z(2)Z(2)/Z(1)Z(2)W(1)W(2) represents the first record among fishes. The presence of different sex chromosome systems in Ancistrus indicates a probable independent origin and suggests that the differentiation of sex chromosomes is evolutionarily recent among species in this genus.

  13. Non-Ideal p-n junction Diode of Sb{sub x}Se{sub 1-x}(x = 0.4, 0.5, 0.6, 0.7) Thin Films

    SciTech Connect

    Mustafa, Falah I.; Gupta, Shikha; Goyal, N.; Tripathi, S. K.

    2011-12-12

    We have made diodes consisting of the same alloy i.e. Sb{sub x}Se{sub 1-x}(x = 0.4, 0.5, 0.6 and 0.7), but change the concentration of Sb metal from 40% to 70% atomic weight percentage. It is observed from the Hall measurements that the nature of charge carriers have changed from p- to n-type at x = 0.6 for Sb{sub x}Se{sub 1-x}. We have measured I-V characteristics of four p-n junction diodes i.e. p-Sb{sub 2}Se{sub 3}/n-Sb{sub 3}Se{sub 2}, p-Sb{sub 2}Se{sub 3}/n-Sb{sub 7}Se{sub 3}, p-SbSe/n-Sb{sub 3}Se{sub 2}, p-SbSe/n-Sb{sub 7}Se{sub 3}. From the I-V plots we have calculated the parameters as built-in voltage (V{sub bi}), forward resistance (R{sub f}), ideal factor (n), saturation current (I{sub o}), breakdown current (I{sub Bd}) and breakdown voltage (V{sub Bd}).

  14. Fatal Outcome in a Newborn Calf Associated with Partial Trisomy 25q and Partial Monosomy 11q, 60,XX,der(11)t(11;25)(q11;q14∼21).

    PubMed

    Iannuzzi, Alessandra; Genualdo, Viviana; Perucatti, Angela; Pauciullo, Alfredo; Varricchio, Giovanna; Incarnato, Domenico; Matassino, Donato; Iannuzzi, Leopoldo

    2015-01-01

    A newborn calf of the Agerolese cattle breed underwent clinical cytogenetic investigation because of hyperflexion of the forelimbs, red eyes and the inability to stand. Anamnesis revealed that the mother, phenotypically normal, carried a chromosomal aberration. The newborn died after 2 weeks, and no remarkable alterations were found by the veterinarian on postmortem examination. The mother was a carrier of a reciprocal balanced translocation rcp(11;25)(q11,q14∼21) detected after a cytogenetic investigation in 2011; however, the analysis of the newborn revealed a different chromosomal aberration with partial trisomy of chromosome 25 and partial monosomy of chromosome 11. In fact, the results showed both chromosomes 25, one chromosome 11 and only one long derivative chromosome (der11). FISH analysis, performed using BAC clones, confirmed the chromosomes and their regions involved. Finally, both the localization of the breakpoints on band q11 (centromere) of chromosome 11 and band q14-21 of chromosome 25, and the complete loss of the der25 identified the aberration as an unbalanced translocation 60,XX,der(11)t(11;25)(q11;q14∼21). A comparison with human chromosomes was also performed to search for similarities and possible genes involved in order to study their effects, thus extending the knowledge of these aberrations by case reports.

  15. Mixed-Halide CH3 NH3 PbI3-x Xx (X=Cl, Br, I) Perovskites: Vapor-Assisted Solution Deposition and Application as Solar Cell Absorbers.

    PubMed

    Sedighi, Rahime; Tajabadi, Fariba; Shahbazi, Saeed; Gholipour, Somayeh; Taghavinia, Nima

    2016-08-04

    There have been recent reports on the formation of single-halide perovskites, CH3 NH3 PbX3 (X=Cl, Br, I), by means of vapor-assisted solution processing. Herein, the successful formation of mixed-halide perovskites (CH3 NH3 PbI3-x Xx ) by means of a vapor-assisted solution method at ambient atmosphere is reported. The perovskite films are synthesized by exposing PbI2 film to CH3 NH3 X (X=I, Br, or Cl) vapor. The prepared perovskite films have uniform surfaces with good coverage, as confirmed by SEM images. The inclusion of chlorine and bromine into the structure leads to a lower temperature and shorter reaction time for optimum perovskite film formation. In the case of CH3 NH3 PbI3-x Clx , the optimum reaction temperature is reduced to 100 °C, and the resulting phases are CH3 NH3 PbI3 (with trace Cl) and CH3 NH3 PbCl3 with a ratio of about 2:1. In the case of CH3 NH3 PbI3-x Brx , single-phase CH3 NH3 PbI2 Br is formed in a considerably shorter reaction time than that of CH3 NH3 PbI3 . The mesostructured perovskite solar cells based on CH3 NH3 PbI3 films show the best optimal power conversion efficiency of 13.5 %, whereas for CH3 NH3 PbI3-x Clx and CH3 NH3 PbI3-x Brx the best recorded efficiencies are 11.6 and 10.5 %, respectively. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Draco,Version 6.x.x

    SciTech Connect

    Thompson, Kelly; Budge, Kent; Lowrie, Rob; Rockefeller, Gabriel; Warsa, James; Wollaber, Allan; Chang, Jae; Cleveland, Matthew

    2016-03-03

    Draco is an object-oriented component library geared towards numerically intensive, radiation (particle) transport applications built for parallel computing hardware. It consists of semi-independent packages and a robust build system. The packages in Draco provide a set of components that can be used by multiple clients to build transport codes. The build system can also be extracted for use in clients. Software includes smart pointers, Design-by-Contract assertions, unit test framework, wrapped MPI functions, a file parser, unstructured mesh data structures, a random number generator, root finders and an angular quadrature component.

  17. Planck 2015 results. XX. Constraints on inflation

    NASA Astrophysics Data System (ADS)

    Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Arnaud, M.; Arroja, F.; Ashdown, M.; Aumont, J.; Baccigalupi, C.; Ballardini, M.; Banday, A. J.; Barreiro, R. B.; Bartolo, N.; Battaner, E.; Benabed, K.; Benoît, A.; Benoit-Lévy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bock, J. J.; Bonaldi, A.; Bonavera, L.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Boulanger, F.; Bucher, M.; Burigana, C.; Butler, R. C.; Calabrese, E.; Cardoso, J.-F.; Catalano, A.; Challinor, A.; Chamballu, A.; Chary, R.-R.; Chiang, H. C.; Christensen, P. R.; Church, S.; Clements, D. L.; Colombi, S.; Colombo, L. P. L.; Combet, C.; Contreras, D.; Couchot, F.; Coulais, A.; Crill, B. P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Désert, F.-X.; Diego, J. M.; Dole, H.; Donzelli, S.; Doré, O.; Douspis, M.; Ducout, A.; Dupac, X.; Efstathiou, G.; Elsner, F.; Enßlin, T. A.; Eriksen, H. K.; Fergusson, J.; Finelli, F.; Forni, O.; Frailis, M.; Fraisse, A. A.; Franceschi, E.; Frejsel, A.; Frolov, A.; Galeotta, S.; Galli, S.; Ganga, K.; Gauthier, C.; Giard, M.; Giraud-Héraud, Y.; Gjerløw, E.; González-Nuevo, J.; Górski, K. M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Gudmundsson, J. E.; Hamann, J.; Handley, W.; Hansen, F. K.; Hanson, D.; Harrison, D. L.; Henrot-Versillé, S.; Hernández-Monteagudo, C.; Herranz, D.; Hildebrandt, S. R.; Hivon, E.; Hobson, M.; Holmes, W. A.; Hornstrup, A.; Hovest, W.; Huang, Z.; Huffenberger, K. M.; Hurier, G.; Jaffe, A. H.; Jaffe, T. R.; Jones, W. C.; Juvela, M.; Keihänen, E.; Keskitalo, R.; Kim, J.; Kisner, T. S.; Kneissl, R.; Knoche, J.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lähteenmäki, A.; Lamarre, J.-M.; Lasenby, A.; Lattanzi, M.; Lawrence, C. R.; Leonardi, R.; Lesgourgues, J.; Levrier, F.; Lewis, A.; Liguori, M.; Lilje, P. B.; Linden-Vørnle, M.; López-Caniego, M.; Lubin, P. M.; Ma, Y.-Z.; Macías-Pérez, J. F.; Maggio, G.; Maino, D.; Mandolesi, N.; Mangilli, A.; Maris, M.; Martin, P. G.; Martínez-González, E.; Masi, S.; Matarrese, S.; McGehee, P.; Meinhold, P. R.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mitra, S.; Miville-Deschênes, M.-A.; Molinari, D.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Moss, A.; Münchmeyer, M.; Munshi, D.; Murphy, J. A.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C. B.; Nørgaard-Nielsen, H. U.; Noviello, F.; Novikov, D.; Novikov, I.; Oxborrow, C. A.; Paci, F.; Pagano, L.; Pajot, F.; Paladini, R.; Pandolfi, S.; Paoletti, D.; Pasian, F.; Patanchon, G.; Pearson, T. J.; Peiris, H. V.; Perdereau, O.; Perotto, L.; Perrotta, F.; Pettorino, V.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Popa, L.; Pratt, G. W.; Prézeau, G.; Prunet, S.; Puget, J.-L.; Rachen, J. P.; Reach, W. T.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renault, C.; Renzi, A.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Rossetti, M.; Roudier, G.; Rowan-Robinson, M.; Rubiño-Martín, J. A.; Rusholme, B.; Sandri, M.; Santos, D.; Savelainen, M.; Savini, G.; Scott, D.; Seiffert, M. D.; Shellard, E. P. S.; Shiraishi, M.; Spencer, L. D.; Stolyarov, V.; Stompor, R.; Sudiwala, R.; Sunyaev, R.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J. A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Trombetti, T.; Tucci, M.; Tuovinen, J.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vielva, P.; Villa, F.; Wade, L. A.; Wandelt, B. D.; Wehus, I. K.; White, M.; Yvon, D.; Zacchei, A.; Zibin, J. P.; Zonca, A.

    2016-09-01

    We present the implications for cosmic inflation of the Planck measurements of the cosmic microwave background (CMB) anisotropies in both temperature and polarization based on the full Planck survey, which includes more than twice the integration time of the nominal survey used for the 2013 release papers. The Planck full mission temperature data and a first release of polarization data on large angular scales measure the spectral index of curvature perturbations to be ns = 0.968 ± 0.006 and tightly constrain its scale dependence to dns/ dlnk = -0.003 ± 0.007 when combined with the Planck lensing likelihood. When the Planck high-ℓ polarization data are included, the results are consistent and uncertainties are further reduced. The upper bound on the tensor-to-scalar ratio is r0.002< 0.11 (95% CL). This upper limit is consistent with the B-mode polarization constraint r< 0.12 (95% CL) obtained from a joint analysis of the BICEP2/Keck Array and Planck data. These results imply that V(φ) ∝ φ2 and natural inflation are now disfavoured compared to models predicting a smaller tensor-to-scalar ratio, such as R2 inflation. We search for several physically motivated deviations from a simple power-law spectrum of curvature perturbations, including those motivated by a reconstruction of the inflaton potential not relying on the slow-roll approximation. We find that such models are not preferred, either according to a Bayesian model comparison or according to a frequentist simulation-based analysis. Three independent methods reconstructing the primordial power spectrum consistently recover a featureless and smooth PR(k) over the range of scales 0.008 Mpc-1 ≲ k ≲ 0.1 Mpc-1. At large scales, each method finds deviations from a power law, connected to a deficit at multipoles ℓ ≈ 20-40 in the temperature power spectrum, but at an uncompelling statistical significance owing to the large cosmic variance present at these multipoles. By combining power spectrum and non-Gaussianity bounds, we constrain models with generalized Lagrangians, including Galileon models and axion monodromy models. The Planck data are consistent with adiabatic primordial perturbations, and the estimated values for the parameters of the base Λ cold dark matter (ΛCDM) model are not significantly altered when more general initial conditions are admitted. In correlated mixed adiabatic and isocurvature models, the 95% CL upper bound for the non-adiabatic contribution to the observed CMB temperature variance is | αnon - adi | < 1.9%, 4.0%, and 2.9% for CDM, neutrino density, and neutrino velocity isocurvature modes, respectively. We have tested inflationary models producing an anisotropic modulation of the primordial curvature power spectrum findingthat the dipolar modulation in the CMB temperature field induced by a CDM isocurvature perturbation is not preferred at a statistically significant level. We also establish tight constraints on a possible quadrupolar modulation of the curvature perturbation. These results are consistent with the Planck 2013 analysis based on the nominal mission data and further constrain slow-roll single-field inflationary models, as expected from the increased precision of Planck data using the full set of observations.

  18. Kharkiv Meteor Radar System (the XX Age)

    NASA Astrophysics Data System (ADS)

    Kolomiyets, S. V.

    2012-09-01

    Kharkiv meteor radar research are of historic value (Kolomiyets and Sidorov 2007). Kharkiv radar observations of meteors proved internationally as the best in the world, it was noted at the IAU General Assembly in 1958. In the 1970s Kharkiv meteor automated radar system (MARS) was recommended at the international level as a successful prototype for wide distribution. Until now, this radar system is one of the most sensitive instruments of meteor radars in the world for astronomical observations. In 2004 Kharkiv meteor radar system is included in the list of objects which compose the national property of Ukraine. Kharkiv meteor radar system has acquired the status of the important historical astronomical instrument in world history. Meteor Centre for researching meteors in Kharkiv is a analogue of the observatory and performs the same functions of a generator and a battery of special knowledge and skills (the world-famous studio). Kharkiv and the location of the instrument were brand points on the globe, as the place where the world-class meteor radar studies were carried out. They are inscribed in the history of meteor astronomy, in large letters and should be immortalized on a world-wide level.

  19. Planck 2015 results: XX. Constraints on inflation

    DOE PAGES

    Ade, P. A. R.; Aghanim, N.; Arnaud, M.; ...

    2016-09-20

    In this paper, we present the implications for cosmic inflation of the Planck measurements of the cosmic microwave background (CMB) anisotropies in both temperature and polarization based on the full Planck survey, which includes more than twice the integration time of the nominal survey used for the 2013 release papers. The Planck full mission temperature data and a first release of polarization data on large angular scales measure the spectral index of curvature perturbations to be ns = 0.968 ± 0.006 and tightly constrain its scale dependence to dns/ dlnk = -0.003 ± 0.007 when combined with the Planck lensingmore » likelihood. When the Planck high-ℓ polarization data are included, the results are consistent and uncertainties are further reduced. The upper bound on the tensor-to-scalar ratio is r0.002< 0.11 (95% CL). This upper limit is consistent with the B-mode polarization constraint r< 0.12 (95% CL) obtained from a joint analysis of the BICEP2/Keck Array and Planck data. These results imply that V(φ) ∝ φ2 and natural inflation are now disfavoured compared to models predicting a smaller tensor-to-scalar ratio, such as R2 inflation. We search for several physically motivated deviations from a simple power-law spectrum of curvature perturbations, including those motivated by a reconstruction of the inflaton potential not relying on the slow-roll approximation. We find that such models are not preferred, either according to a Bayesian model comparison or according to a frequentist simulation-based analysis. Three independent methods reconstructing the primordial power spectrum consistently recover a featureless and smooth PR(k)over the range of scales 0.008 Mpc-1 ≲ k ≲ 0.1 Mpc-1. At large scales, each method finds deviations from a power law, connected to a deficit at multipoles ℓ ≈ 20-40 in the temperature power spectrum, but at an uncompelling statistical significance owing to the large cosmic variance present at these multipoles. By combining power spectrum and non-Gaussianity bounds, we constrain models with generalized Lagrangians, including Galileon models and axion monodromy models. The Planck data are consistent with adiabatic primordial perturbations, and the estimated values for the parameters of the base Λ cold dark matter (ΛCDM) model are not significantly altered when more general initial conditions are admitted. In correlated mixed adiabatic and isocurvature models, the 95% CL upper bound for the non-adiabatic contribution to the observed CMB temperature variance is | αnon - adi | < 1.9%, 4.0%, and 2.9% for CDM, neutrino density, and neutrino velocity isocurvature modes, respectively. We have tested inflationary models producing an anisotropic modulation of the primordial curvature power spectrum finding that the dipolar modulation in the CMB temperature field induced by a CDM isocurvature perturbation is not preferred at a statistically significant level. We also establish tight constraints on a possible quadrupolar modulation of the curvature perturbation. Lastly, these results are consistent with the Planck 2013 analysis based on the nominal mission data and further constrain slow-roll single-field inflationary models, as expected from the increased precision of Planck data using the full set of observations.« less

  20. The Function sin x/x.

    ERIC Educational Resources Information Center

    Gearhart, William B.; Shultz, Harris S.

    1990-01-01

    Presents some examples from geometry: area of a circle; centroid of a sector; Buffon's needle problem; and expression for pi. Describes several roles of the trigonometric function in mathematics and applications, including Fourier analysis, spectral theory, approximation theory, and numerical analysis. (YP)

  1. XX International Workshop on Condensed Matter Theories

    DTIC Science & Technology

    1998-01-01

    Density Matrix Theory J. W. Clark, M. L. Ristig, T. Lindenau and M. Serhan 7 Can BCS and BEC be Synthesized? V. C. Aguilera-Navarro, M. Casas, S...Louis, MO 63130 USA M. L. Ristig, T. Lindenau, and M. Serhan Institut für Theoretische Physik Universität zu Köln, D-50937 Köln, Germany 1...E. Campbell, and J. W. Clark, Ann. Phys. (N.Y.) 218, 116 (1992). [10] M. L. Ristig, G. Senger, M. Serhan , and J. W. Clark, Ann. Phys. (N.Y.) 243

  2. Cytogenetic analysis of 1572 cases of Down syndrome: a report of double aneuploidy and novel findings 47,XY, t(14;21)(q13;q22.3)mat,+21 and 45,XX,t(14;21) in an Indian population.

    PubMed

    Mandava, Swarna; Koppaka, Neeraja; Bhatia, Vinay; Das, Bibhu Ranjan

    2010-08-01

    Down syndrome (DS) is the most common genetic reason for learning disability and congenital malformations in the human population, occurring with an incidence of 1 in 650-1000 newborns. The aim of this study was to perform chromosome analysis in suspected DS cases with clinical features such as dysmorphism, epicanthic folds, simian crease, and hypotonia, referred to Super Religare Laboratories, Mumbai, India. Cytogenetic analysis of peripheral blood lymphocyte cultures was performed at 550-band level using the modified standard protocol. In this study, male:female sex ratio of DS patients was found to be 1.84:1. Among 1572 cases of DS, standard trisomy 21 in 1400 (89.05%) cases, Robertsonian translocation in 111 (7.06%) cases, and Mosaic form in 28 (1.78%) cases were observed. Three cases of double aneuploidy mos 47,XY,+21/47,XXY and one case of mosaic double aneuploidy mos 47,XY,+21/48,XXY,+21 were noticed. In addition, two novel findings 47,XY,t(14;21)(q13;q22.3)mat,+21 and 45,XX,t(14;21) with DS features are presented. In this study, 1572 cases were confirmed as DS, of which maximum cases showed standard trisomy 21. Parental karyotyping and genetic counseling were recommended for the cases confirmed as DS after chromosome analysis.

  3. The motley family of polar compounds (MV)[M(X{sub 5-x}X Prime {sub x})] based on anionic chains of trans-connected M{sup (III)}(X,X Prime ){sub 6} octahedra (M=Bi, Sb; X, X Prime =Cl, Br, I) and methylviologen (MV) dications

    SciTech Connect

    Leblanc, Nicolas; Mercier, Nicolas; Allain, Magali; Toma, Oksana; Auban-Senzier, Pascale; Pasquier, Claude

    2012-11-15

    The search for hybrid organic-inorganic materials remains a great challenge in the field of ferroelectrics. Following the discovery of the room temperature ferroelectric material (MV)[BiI{sub 3}Cl{sub 2}] (MV{sup 2+}: methylviologen) exhibiting the highest polarization value in the field of hybrid ferroelectrics, we report here nine new hybrids with the general formulation (MV)[M{sup (III)}X{sub 5-x}X Prime {sub x}] (M=Bi, Sb; X, X Prime =Cl, Br, I): (MV)[BiCl{sub 3.3}Br{sub 1.7}] (1), (MV)[BiCl{sub 1.3}Br{sub 3.7}] (2), (MV)[BiBr{sub 3.2}I{sub 1.8}] (3), (MV)[SbCl{sub 5}] (4), (MV)[SbBr{sub 5}] (5), (MV)[SbCl{sub 3.8}Br{sub 1.2}] (6), (MV)[SbCl{sub 2.4}Br{sub 2.6}] (7), (MV)[SbI{sub 3}Cl{sub 2}] (8) and (MV)[SbBr{sub 3.8}I{sub 1.2}] (9). Depending on the presence of polar chains or not, and on the coupling of polar chains, two types of centrosymmetrical structures [C1] and [C2] and two types of polar structures [P1] and [P2] are defined. (2) undergoes a paraelectric-to-relaxor ferroelectric transition around 100-150 K depending of the frequency showing that the Curie temperature, T{sub C}, of (MV)[BiBr{sub 5}] (243 K) can be modulated by the substitution of Br by Cl. The most interesting family is the [P2] type because the syn coupling of polar chains is in favor of high polarization values, as in (MV)[BiI{sub 3}Cl{sub 2}]. Five of the nine new hybrids, (4), (6-9), which have the [P2] type structure are potential ferroelectrics. - Graphical abstract: The methylviologen haloantimonate (MV)[SbX{sub 5-x}X Prime {sub x}] families (X, X Prime =Cl, Br, I) - [P1] and [P2] are the two kinds of polar structures - and view of the (MV)[SbBr{sub 3.8}I{sub 1.2}] hybrid based on chiral polar chains which are in syn coupling. Highlights: Black-Right-Pointing-Pointer Nine hybrids based on methylviologen and halometalate chains have been discovered. Black-Right-Pointing-Pointer The polar nature of chains is due to the ns{sup 2} stereoactivity of Sb{sup (III)} or Bi{sup (III

  4. [The medicine in Mexico in the XX century].

    PubMed

    Flisser, Ana

    2009-01-01

    The end of the 19th and the beginning of the 20th century constitute a breakthrough in medicine. The Industrial Revolution was soon followed by a revolution in medicine characterized by a similar pattern where novel technology was produced. This initiated the transformation of medicine as a science and the establishment of medical specialties as we know them to date. Mexicans physicians must be commended for quickly adapting to this new way of thinking and practicing medicine. Important changes in clinical practice and in the medical community took place and were associated with the creation of several medical institutions. The field of public health grew as a medical concept focused on the individual and the population.

  5. Speckle Interferometry at the U.S. Naval Observatory. XX

    NASA Astrophysics Data System (ADS)

    Hartkopf, William I.; Mason, Brian D.

    2015-10-01

    Results are presented of 4222 intensified CCD observations of double stars, made with the 26 inch refractor of the U.S. Naval Observatory in 2013 and 2014. These observations are averaged into 2335 mean relative positions and range in separation from 0.″53 to 83.″90, with a median separation of 11.″42. This is the 20th in this series of papers and covers the period 2013 January 4 through 2014 December 18. Also presented are 13 pairs which are measured for the first time, 12 pairs which appear to be lost, linear elements for 17 pairs, and orbital elements for five additional pairs. Finally, we investigated apparent systematic residuals to earlier measures in this series, and modify scale factors for closer pairs observed between 1990 and the present.

  6. Vulvar fetal rhabdomyoma mimicking 46XX sex differentiation disorder.

    PubMed

    Martos-Moreno, Gabriel Ángel; de Prada, Inmaculada; Riñón, Cristina; Argente, Jesús

    2016-02-01

    Rhabdomiomas are rare mesenchymal benign tumors of striated muscle origin. Setting aside the cardiac (most atrial) rhabdomiomas typically associated to neurocutaneous syndromes (tuberous sclerosis), extracardiac rhabdomyomas appear clinically as a subcutaneous nodule or as a submucosal polypoid lesion. Among them, three main histologic subtypes can be differentiated on the basis of the degree of tumor differentiation: 1) fetal rhabdomioma, usually diagnosed during childhood and almost exclusively located in the in the head and neck region with rare reports in other locations; 2) adult rhabdomioma; and 3) genital rhabdomioma, reported to occur in the lower genital tract of young and middle-aged women and, exceptionally, in children (5).

  7. Wood Anatomy of the Neotropical Sapotaceae. XX. Manilkara

    DTIC Science & Technology

    1981-06-01

    were placed in synonomy under Manilkara mayarensis (Ekm.) Cronq. (3). In his studies of the " Sapodilla -Nispero complex," Gilly (7) created four new...new species from Haiti. Trop. Woods 71:3-6. 7. Gilly, Charles L. 1943. Studies in the Sapotaceae. II. The Sapodilla -Nispero complex. Trop. Woods 73:1

  8. Commissary Services: AFSC 612XX and Civilian Equivalent

    DTIC Science & Technology

    1992-02-01

    level into a common DAFSC of 61272. The 7-skill level personnel supervise subsistence and meat processing functions in commissary and troop support...unique to meat processing functions. Seventy-one percent of their time is spent on Duty K - performing meat department management and meatcutter...meatcutters perform almost exclusively meatcutting and meat processing tasks. This is reflected in the fact that 86 percent of this group work in the

  9. Communications-Electronics Utilization Field AFSC 30XX.

    DTIC Science & Technology

    1984-08-01

    needed modification in the type and amount of electronics principles training given to entry-level officers. This finding has not changed over the...intervening 10 years. The 1984 survey indicates a need to review the electronics principles blocks of instruction. While there can be no argument that

  10. Serendipitous images of methanol in Comet Levy (1900 XX)

    NASA Technical Reports Server (NTRS)

    Hoban, Susan

    1993-01-01

    Reuter's (1992) model of the IR fluorescence of methanol is used to retrieve a methanol production rate of 3 +/- 1 x 10 exp 26/s and an abundance relative to water of about 0.1 percent. It is argued that calibration is of paramount importance and that a near-simultaneous spectrum is necessary for achieving a reliable estimate of the continuum underlying the emission feature.

  11. The Evolution from Generation to Post-XX

    ERIC Educational Resources Information Center

    Feng, Zhao

    2011-01-01

    Young people represent the future, and youth is an eternal topic. In the 1970s when the American anthropologist Margaret Mead published her famous work "Generation Gap," research on generations gained sudden popularity worldwide, and ever since the 1980s when "Generation Gap" was brought to China, research by scholars in this…

  12. The Path of Carbon in Photosynthesis XX. The Steady State

    DOE R&D Accomplishments Database

    Calvin, M.; Massini, Peter

    1952-09-01

    The separation of the phenomenon of photosynthesis in green plants into a photochemical reaction and into the light-dependent reduction of carbon dioxide is discussed, The reduction of carbon dioxide and the fate of the assimilated carbon were investigated with the help of the tracer technique (exposure of the planks to the radioactive C{sup 14}O{sub 2}) and of paper chromatography. A reaction cycle is proposed in which phosphoglyceric acid is the first isolable assimilations product. Analyses of the algal extracts which had assimilated radioactive carbon dioxide in a stationary condition ('steady-state' photosynthesis) for a long time provided further information concerning the proposed cycle and permitted the approximate estimation, for a number of compounds of what fraction of each compound was taking part in the cycle. The earlier supposition that light influences the respiration cycle was confirmed. The possibility of the assistance of {alpha}-lipoic acid, or of a related substance, in this influence and in the photosynthesis cycle, is discussed.

  13. ICPEAC XX: A Retro- and Pro-Spective Analysis

    SciTech Connect

    Datz, S.

    1997-12-31

    There is something magical about ``round birthdays.`` They make one stop and think about where he is, how he got there, and where he is going. The same is apparently true of conferences, especially those like ICPEAC which represent the periodic coming together of a broad range of scientists in a reasonably well-defined discipline. This Vienna conference is the 20th in the ICPEAC series, and a retro- and pro-spective analysis seems appropriate. At the first ICPEAC in New York (1958), there were about 50 participants. In Vienna (1997), there were more than 800 participants. How do we account for this growth? ICPEAC is one of the most democratic conferences of its size. For example, input from a general committee of 50 representing the many geographic and sub- disciplinary areas gives continuous refreshment of ideas for the invited program. And, as in any democracy, there is a constant state of turmoil and self doubt. After all, atomic collisions is a ``mature`` field, and was a ``mature`` field at the time of the first ICPEAC in 1958, 50 what can one expect in new developments? This self doubt is best expressed in the comment of Ben Bederson (the ``Father of ICPEAC``) following the second in Boulder, Colorado, in 1961: ``This conference is the second in a series of informal meetings organized by a group of workers in the general field of electronic and atomic collisions. The first such meeting was held at New York University in 1958, and we will probably continue to meet at irregular intervals in the future....`` As part of my ``keynote`` talk at the New York ICPEAC XVI in 1989, I gave a brief history of the conference which we can build on to round things off for our twentieth.

  14. The need for a paradigm shift in toxicology xx.

    EPA Science Inventory

    This manuscript briefly reviews the impact of the NAS report “Toxicity Testing in the 21st Century: A Vision and A Strategy” and it’s potential impact on the field of toxicology. ). This report provides a strategic and tactical framework for attaining the goals of deter...

  15. Treating epilepsy in Italy between XIX and XX century.

    PubMed

    Tagarelli, Giuseppe; Tagarelli, Antonio; Liguori, Maria; Piro, Anna

    2013-01-30

    Epilepsy is a neurological disorder which has been recognized since antiquity. This paper evaluates the prophylactic and therapeutic remedies used by folk medicine to cure epilepsy in Italy. The data has been collected by reviewing written sources of physicians, ethnographers, folklorists between the late nineteenth and mid twentieth century. This approach leads to unearthing of 78 heterogeneous healing methods that have been divided into 16 (20%) magical, 20 (26%) religious and 42 (54%) natural remedies. The latter has been subdivided into 18 (43%) animal remedies, 17 (40%) plant remedies and 7 (17%) other remedies. Religious and magical remedies were used with the conviction that they would be able to provide recovery from epilepsy and to ward off evil spirits which had taken possession of the sick. Interestingly, the herbal remedies highlighted 12 (70%) plants that play or might play an important role with respect to the mechanisms that generate the epileptic seizures. This leads us to reconsider the historical significance of folk medicine, too often it is underestimated owing to its use of ineffective remedies, born of incompetence and superstition.

  16. XX1 Asian chestnut gall wasp (Dryocosmus kuriphilus) (Hymenoptera: Cynipidae)

    USDA-ARS?s Scientific Manuscript database

    The Asian chestnut gall wasp, Dryocosmus kuriphilus, is an invasive pest of chestnut in Japan, Europe, and the United States. D. kuriphilus induces formation of galls on all chestnut species. Damage caused by galling reduces commercial chestnut yields and threatens restoration of American chestnut i...

  17. Chapter XX: POLYMODAL SENSORY INTEGRATION IN RETINAL GANGLION CELLS

    PubMed Central

    Križaj, David

    2016-01-01

    An animal's ability to perceive the external world is conditioned by its capacity to extract and encode specific features of the visual image. The output of the vertebrate retina is not a simple representation of the 2D visual map generated by photon absorptions in the photoreceptor layer. Rather, spatial, temporal, direction selectivity and color “dimensions” of the original image are distributed in the form of parallel output channels mediated by distinct retinal ganglion cell (RGC) populations. We propose that visual information transmitted to the brain includes additional, light-independent, inputs that reflect the functional states of the retina, anterior eye and the body. These may include the local ion microenvironment, glial metabolism and systemic parameters such as intraocular pressure, temperature and immune activation which act on ion channels that are intrinsic to RGCs. We particularly focus on light-independent mechanical inputs that are associated with physical impact, cell swelling and intraocular pressure as excessive mechanical stimuli lead to the counterintuitive experience of “pressure phosphenes” and/or debilitating blinding disease such as glaucoma and diabetic retinopathy. We point at recently discovered retinal mechanosensitive ion channels as examples through which molecular physiology brings together Greek phenomenology, modern neuroscience and medicine. Thus, RGC output represents a unified picture of the embodied context within which vision takes place. PMID:26427477

  18. AUTOMOTIVE DIESEL MAINTENANCE 2. UNIT XX, TROUBLESHOOTING ELECTRICAL SYSTEMS.

    ERIC Educational Resources Information Center

    Minnesota State Dept. of Education, St. Paul. Div. of Vocational and Technical Education.

    THIS MODULE OF A 25-MODULE COURSE IS DESIGNED TO ACQUAINT THE TRAINEE WITH TROUBLESHOOTING PROCEDURES FOR DIESEL ENGINE ELECTRICAL SYSTEMS. TOPICS ARE (1) TROUBLESHOOTING ELECTRICAL SYSTEMS (INTRODUCTION), (2) TOOLS AND INSTRUMENTS FOR TROUBLESHOOTING, (3) THE BATTERY, (4) PERIODIC BATTERY SERVICING, (5) THE DC CHARGING SYSTEM, (6) PERIODIC…

  19. The Evolution from Generation to Post-XX

    ERIC Educational Resources Information Center

    Feng, Zhao

    2011-01-01

    Young people represent the future, and youth is an eternal topic. In the 1970s when the American anthropologist Margaret Mead published her famous work "Generation Gap," research on generations gained sudden popularity worldwide, and ever since the 1980s when "Generation Gap" was brought to China, research by scholars in this…

  20. Planck 2015 results: XX. Constraints on inflation

    SciTech Connect

    Ade, P. A. R.; Aghanim, N.; Arnaud, M.; Arroja, F.; Ashdown, M.; Aumont, J.; Baccigalupi, C.; Ballardini, M.; Banday, A. J.; Barreiro, R. B.; Bartolo, N.; Battaner, E.; Benabed, K.; Benoît, A.; Benoit-Lévy, A.; Bernard, J. -P.; Bersanelli, M.; Bielewicz, P.; Bock, J. J.; Bonaldi, A.; Bonavera, L.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Boulanger, F.; Bucher, M.; Burigana, C.; Butler, R. C.; Calabrese, E.; Cardoso, J. -F.; Catalano, A.; Challinor, A.; Chamballu, A.; Chary, R. -R.; Chiang, H. C.; Christensen, P. R.; Church, S.; Clements, D. L.; Colombi, S.; Colombo, L. P. L.; Combet, C.; Contreras, D.; Couchot, F.; Coulais, A.; Crill, B. P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Désert, F. -X.; Diego, J. M.; Dole, H.; Donzelli, S.; Doré, O.; Douspis, M.; Ducout, A.; Dupac, X.; Efstathiou, G.; Elsner, F.; Enßlin, T. A.; Eriksen, H. K.; Fergusson, J.; Finelli⋆, F.; Forni, O.; Frailis, M.; Fraisse, A. A.; Franceschi, E.; Frejsel, A.; Frolov, A.; Galeotta, S.; Galli, S.; Ganga, K.; Gauthier, C.; Giard, M.; Giraud-Héraud, Y.; Gjerløw, E.; González-Nuevo, J.; Górski, K. M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Gudmundsson, J. E.; Hamann, J.; Handley, W.; Hansen, F. K.; Hanson, D.; Harrison, D. L.; Henrot-Versillé, S.; Hernández-Monteagudo, C.; Herranz, D.; Hildebrandt, S. R.; Hivon, E.; Hobson, M.; Holmes, W. A.; Hornstrup, A.; Hovest, W.; Huang, Z.; Huffenberger, K. M.; Hurier, G.; Jaffe, A. H.; Jaffe, T. R.; Jones, W. C.; Juvela, M.; Keihänen, E.; Keskitalo, R.; Kim, J.; Kisner, T. S.; Kneissl, R.; Knoche, J.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lähteenmäki, A.; Lamarre, J. -M.; Lasenby, A.; Lattanzi, M.; Lawrence, C. R.; Leonardi, R.; Lesgourgues, J.; Levrier, F.; Lewis, A.; Liguori, M.; Lilje, P. B.; Linden-Vørnle, M.; López-Caniego, M.; Lubin, P. M.; Ma, Y. -Z.; Macías-Pérez, J. F.; Maggio, G.; Maino, D.; Mandolesi, N.; Mangilli, A.; Maris, M.; Martin, P. G.; Martínez-González, E.; Masi, S.; Matarrese, S.; McGehee, P.; Meinhold, P. R.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mitra, S.; Miville-Deschênes, M. -A.; Molinari, D.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Moss, A.; Münchmeyer, M.; Munshi, D.; Murphy, J. A.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C. B.; Nørgaard-Nielsen, H. U.; Noviello, F.; Novikov, D.; Novikov, I.; Oxborrow, C. A.; Paci, F.; Pagano, L.; Pajot, F.; Paladini, R.; Pandolfi, S.; Paoletti, D.; Pasian, F.; Patanchon, G.; Pearson, T. J.; Peiris, H. V.; Perdereau, O.; Perotto, L.; Perrotta, F.; Pettorino, V.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Popa, L.; Pratt, G. W.; Prézeau, G.; Prunet, S.; Puget, J. -L.; Rachen, J. P.; Reach, W. T.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renault, C.; Renzi, A.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Rossetti, M.; Roudier, G.; Rowan-Robinson, M.; Rubiño-Martín, J. A.; Rusholme, B.; Sandri, M.; Santos, D.; Savelainen, M.; Savini, G.; Scott, D.; Seiffert, M. D.; Shellard, E. P. S.; Shiraishi, M.; Spencer, L. D.; Stolyarov, V.; Stompor, R.; Sudiwala, R.; Sunyaev, R.; Sutton, D.; Suur-Uski, A. -S.; Sygnet, J. -F.; Tauber, J. A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Trombetti, T.; Tucci, M.; Tuovinen, J.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vielva, P.; Villa, F.; Wade, L. A.; Wandelt, B. D.; Wehus, I. K.; White, M.; Yvon, D.; Zacchei, A.; Zibin, J. P.; Zonca, A.

    2016-09-20

    In this paper, we present the implications for cosmic inflation of the Planck measurements of the cosmic microwave background (CMB) anisotropies in both temperature and polarization based on the full Planck survey, which includes more than twice the integration time of the nominal survey used for the 2013 release papers. The Planck full mission temperature data and a first release of polarization data on large angular scales measure the spectral index of curvature perturbations to be ns = 0.968 ± 0.006 and tightly constrain its scale dependence to dns/ dlnk = -0.003 ± 0.007 when combined with the Planck lensing likelihood. When the Planck high-ℓ polarization data are included, the results are consistent and uncertainties are further reduced. The upper bound on the tensor-to-scalar ratio is r0.002< 0.11 (95% CL). This upper limit is consistent with the B-mode polarization constraint r< 0.12 (95% CL) obtained from a joint analysis of the BICEP2/Keck Array and Planck data. These results imply that V(φ) ∝ φ2 and natural inflation are now disfavoured compared to models predicting a smaller tensor-to-scalar ratio, such as R2 inflation. We search for several physically motivated deviations from a simple power-law spectrum of curvature perturbations, including those motivated by a reconstruction of the inflaton potential not relying on the slow-roll approximation. We find that such models are not preferred, either according to a Bayesian model comparison or according to a frequentist simulation-based analysis. Three independent methods reconstructing the primordial power spectrum consistently recover a featureless and smooth PR(k)over the range of scales 0.008 Mpc-1 ≲ k ≲ 0.1 Mpc-1. At large scales, each method finds deviations from a power law, connected to a deficit at multipoles ℓ ≈ 20-40 in the temperature power spectrum, but at an uncompelling statistical significance owing to the large cosmic variance present at these multipoles. By combining power spectrum and non-Gaussianity bounds, we constrain models with generalized Lagrangians, including Galileon models and axion monodromy models. The Planck data are consistent with adiabatic primordial perturbations, and the estimated values for the parameters of the base Λ cold dark matter (ΛCDM) model are not significantly altered when more general initial conditions are admitted. In correlated mixed adiabatic and isocurvature models, the 95% CL upper bound for the non-adiabatic contribution to the observed CMB temperature variance is | αnon - adi | < 1.9%, 4.0%, and 2.9% for CDM, neutrino density, and neutrino velocity isocurvature modes, respectively. We have tested inflationary models producing an anisotropic modulation of the primordial curvature power spectrum finding that the dipolar modulation in the CMB temperature field induced by a CDM isocurvature perturbation is not preferred at a statistically significant level. We also establish tight constraints on a possible quadrupolar modulation of the curvature perturbation. Lastly, these results are consistent with the Planck 2013 analysis based on the nominal mission data and further constrain slow-roll single-field inflationary models, as expected from the increased precision of Planck data using the full set of observations.

  1. Oral Histories in Meteoritics and Planetary Science - XX: Dale Cruikshank

    NASA Astrophysics Data System (ADS)

    Sears, Derek W. G.

    2013-04-01

    In this interview, Dale Cruikshank (Fig. 1) explains how as an undergraduate at Iowa State University he was a summer student at Yerkes Observatory where he assisted Gerard Kuiper in work on his Photographic Lunar Atlas. Upon completing his degree, Dale went to graduate school at the University of Arizona with Kuiper where he worked on the IR spectroscopy of the lunar surface. After an eventful 1968 trip to Moscow via Prague, during which the Soviets invaded Czechoslovakia, Dale assumed a postdoc position with Vasili Moroz at the Sternberg Astronomical Institute and more observational IR astronomy. Upon returning to the United States and after a year at Arizona, Dale assumed a position at the University of Hawai'i that he held for 17 years. During this period Dale worked with others on thermal infrared determinations of the albedos of small bodies beyond the asteroid Main Belt, leading to the recognition that low-albedo material is prevalent in the outer solar system that made the first report of complex organic solids on a planetary body (Saturn's satellite Iapetus). After moving to Ames Research Center, where he works currently, he continued this work and became involved in many outer solar system missions. Dale has served the community through his involvement in developing national policies for science-driven planetary exploration, being chair of the DPS 1990-1991 and secretary/treasurer for 1982-1985. He served as president of Commission 16 (Physics of Planets) of the IAU (2001-2003). He received the Kuiper prize in 2006.

  2. Conducting Slug Tests in Mini-Piezometers: B.G. Fritz Ground Water xx, no. x: x-xx

    SciTech Connect

    Fritz, Bradley G.; Mackley, Rob D.; Arntzen, Evan V.

    2015-03-26

    Slug tests performed using mini-piezometers with diameters as small as 0.43 cm can provide a cost effective tool for hydraulic characterization. We evaluated the hydraulic properties of the apparatus in an infinite hydraulic conductivity environment and compared those results with field tests of mini-piezometers installed into locations with varying hydraulic properties. Based on our evaluation, slug tests conducted in mini-piezometers using the fabrication and installation approach described here are effective within formations where the hydraulic conductivity is less than 1 x 10-3 cm/s. While these constraints limit the potential application of this method, the benefits to this approach are that the installation, measurement and analysis is extremely cost effective, and the installation can be completed in areas where other (larger diameter) methods might not be possible. Additionally, this methodology could be applied to existing mini-piezometers previously installed for other purposes. Such analysis of existing installations could be beneficial in interpreting previously collected data (e.g. water quality data or hydraulic head data).

  3. 75 FR 3144 - Airworthiness Directives; Sicma Aero Seat 90xx and 92xx Series Passenger Seats, Installed on, But...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-20

    ...) 2 54 03 39 39; fax +33 (0) 2 54 03 15 16; e-mail: customerservices@sicma.zodiac.com ; Internet http://www.sicma.zodiac.com/en/ . (3) You may review copies of the service information at the FAA,...

  4. 46 CFR Appendix A to Part 535 - Information Form and Instructions

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Time Period: (A)Vessel Capacity (B)Utilization Carrier A Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Carrier B Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Etc. . . . (C) Narrative statement on significant changes...

  5. 46 CFR Appendix B to Part 535 - Monitoring Report and Instructions

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... capacity (B)Utilization Carrier A : Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Carrier B: Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Etc. . . . (C) Narrative statement on significant reductions in vessel capacity...

  6. 46 CFR Appendix B to Part 535 - Monitoring Report and Instructions

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... capacity (B)Utilization Carrier A : Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Carrier B: Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Etc. . . . (C) Narrative statement on significant reductions in vessel capacity to...

  7. 46 CFR Appendix B to Part 535 - Monitoring Report and Instructions

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... capacity (B)Utilization Carrier A : Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Carrier B: Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Etc. . . . (C) Narrative statement on significant reductions in vessel capacity to...

  8. Electrical Characterization of 64K Dynamic Rams.

    DTIC Science & Technology

    1982-01-01

    Xxx xx . ... .. XXXXXXXXXXX xX .X xxXxx)x)c . . .4 X xx......... XXXXXXCXXXXX ~ x L) * xx xx x . XX...x.C x x * xX X x x XX X XX c X XX X XX.t X ... oXx, xX Xx x X x * * x XXX ’ X Xx) x x x XXX . * o X)x : x X XXX . XXX .f .X . ..X XX . ~X g :1...8217 xx SX X7x XX XXX 0 x Xx xxX X X x IX X X XX x XX x x x x X XXX XX x x x x X ))(Xx ..XX XXXXX XXX . * -. . .. . . X X X.. t.)xx x x :rx xx .

  9. Functional Description of the Training and Personnel Systems Technology Information System.

    DTIC Science & Technology

    1980-12-01

    XXX %) ( XXX %) ( XXX ?.) ( XXX ?.) ( XXX ?.) ( XXX ".) ( XXX ?.) ( XXX .) ( XXX .) 6.2 ɠS1> XXX.XX XXX.XX XXX.XX...XXX.XX XXX.XX XXX.XX XXX.XX XXX.XX XXX.XX ETC. ARMY TOTAL XXX.XX XXX.XX XXX.XX XXX.XX XXX.XX XXX.XX XXX.XX XXX.XX XXX.XX ( XXX ?.) ( XXX ?.) ( XXX ?.) ( XXX ... XXX ?.) ( XXX %) ( XXX ?.) ( XXX ?.) ( XXX ?.) NAVY 6.1 ត> XXX.XX XXX.XX XXX.XX XXX.XX XXX.XX XXX.XX XXX.XX XXX.XX XXX.XX (R%) (

  10. Military Citation, Seventh Edition, August 2001

    DTIC Science & Technology

    2001-09-04

    commercial electronic database (LEXIS or Westlaw), cite to the database following the citation format of Bluebook Rule 18.1.1. [Case Name], No. [ ...20xx CAAF LEXIS [ ] (Dec. xx, 20xx). [Case Name], No. [ ], 20xx CCA LEXIS [ ] (Army Ct. Crim. App. Dec. xx, 20xx). [Case Name], No. [ ...20xx CCA LEXIS [ ] (A.F. Ct. Crim. App. Dec. xx, 20xx). [Case Name], No. [ ], 20xx CCA LEXIS [ ] (N-M. Ct. Crim. App. Dec. xx, 20xx

  11. 46 CFR Appendix A to Part 535 - Information Form and Instructions

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Time Period: (A)Vessel Capacity (B)Utilization Carrier A Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Carrier B Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Etc. . . . (C) Narrative statement on significant changes in...

  12. 46 CFR Appendix A to Part 535 - Information Form and Instructions

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Time Period: (A)Vessel Capacity (B)Utilization Carrier A Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Carrier B Liner Service 1 XX,XXX XX Liner Service 2 XX,XXX XX Liner Service 3 XX,XXX XX Etc. . . . Etc. . . . (C) Narrative statement on significant changes in...

  13. Follow-Up Study of 1990 Dental Hygiene Graduates. Volume XX, No. 1.

    ERIC Educational Resources Information Center

    Holt, Marianne; Lucas, John A.

    In a continuing effort to measure the quality of their Dental Hygiene program, explore the need for changes, and substantiate the program's goals for accreditation standards, a follow-up study was conducted of the 1990 Dental Hygiene program graduates from William Rainey Harper (WRHC) College in Palatine, Illinois. A survey was mailed to all 30…

  14. Case Study: Readiness and Total Ownership Cost Analyses for New Fighter Aircraft, F-XX

    DTIC Science & Technology

    2012-11-29

    held research fellowships at the University of Waterloo and the University of Cincinnati. He has worked for Shell Oil, Monsanto Corporation, and...its contacts in the Aerospace Industry Association (AIA) to reach out to like-minded individuals from multiple defense companies . These defense... company engineers were dedicated to rescuing the tarnished image of their profession by developing a design for an affordable, state-of-the-art

  15. 78 FR 10003 - Proposed Collection; Comment Request for Notice 2009-XX (NOT-151370-08)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-12

    ... for Carbon Dioxide Sequestration under Section 45Q. DATES: Written comments should be received on or...: Credit for Carbon Dioxide Sequestration under Section 45Q OMB Number: 1545-2153. Notice Number: Notice... issuance of regulations, relating to the credit for carbon dioxide sequestration (CO 2 sequestration credit...

  16. Emission Measurements of Ultracell XX25 Reformed Methanol Fuel Cell System

    DTIC Science & Technology

    2008-06-01

    combination of electrochemical devices such as fuel cell and battery. Polymer electrolyte membrane fuel cells ( PEMFC ) using hydrogen or liquid...communications and computers, sensors and night vision capabilities. High temperature PEMFC offers some advantages such as enhanced electrode kinetics and better...tolerance of carbon monoxide that will poison the conventional PEMFC . Ultracell Corporation, Livermore, California has developed a first

  17. LOFT experimental measurements uncertainty analyses. Volume XX. Fluid-velocity measurement using pulsed-neutron activation

    SciTech Connect

    Lassahn, G.D.; Taylor, D.J.N.

    1982-08-01

    Analyses of uncertainty components inherent in pulsed-neutron-activation (PNA) measurements in general and the Loss-of-Fluid-Test (LOFT) system in particular are given. Due to the LOFT system's unique conditions, previously-used techniques were modified to make the volocity measurement. These methods render a useful, cost-effective measurement with an estimated uncertainty of 11% of reading.

  18. 49 CFR 1242.35 - Repair and maintenance (account XX-26-41).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... shop repairs between these services on the basis of run-out unit miles of individual locomotive units...) Where the carrier maintains records of heavy shop repair costs by individual locomotive units or classes... locomotive units: (1) The heavy shop repairs shall be separated as indicated in paragraph (a) of this...

  19. 46 XX pure gonadal dysgenesis: an infrequent cause of primary amenorrhoea

    PubMed Central

    Pertusa, Salvador; Palacios, Ana

    2009-01-01

    Amenorrhoea can be primary or secondary. Primary amenorrhoea is a relatively common problem among teenage girls. They usually consult their paediatrician or family doctor. This condition is present in patients with normal secondary sexual characteristics but no menarche by 16 years of age, or patients who have not had menstrual flow by age 14 and are lacking normal secondary sexual characteristics. Gonadal dysgenesis is an infrequent cause for primary amenorrhoea. In this paper, the case of a 16-year-old girl whose mother consulted their family doctor because of worries about her daughter’s lack of menarche is presented. A blood test showed elevated levels of follicle stimulating hormone (FSH) and luteinising hormone (LH) and low levels of oestradiol. An abdominal ultrasound was abnormal. A diagnostic laparoscopy with biopsy of both gonads was performed. Replacement hormonal therapy was applied resulting in normal menstruations after few months. An early diagnosis is extremely important. PMID:21686785

  20. 15 CFR Appendix A to Chapter Xx - Administration of the Trade Agreements Program

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... authorized by the President or by the Special Representative. Sec. 5. Import Relief and Market Disruption. (a... quantitative restrictions proclaimed in order to provide import relief and is authorized to issue, under... Southeast Asia), and shall prepare, for the President's transmission to Congress, the reports and...

  1. 15 CFR Appendix A to Chapter Xx - Administration of the Trade Agreements Program

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... authorized by the President or by the Special Representative. Sec. 5. Import Relief and Market Disruption. (a... quantitative restrictions proclaimed in order to provide import relief and is authorized to issue, under... Southeast Asia), and shall prepare, for the President's transmission to Congress, the reports and...

  2. 76 FR 54507 - Proposed Generic Communication; Draft NRC Generic Letter 2011-XX: Seismic Risk Evaluations for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-01

    ... individual plant examinations of external events (IPEEE) and Generic Issue (GI)-199, ``Implications of.... ML051450456), that the ] issue of increased seismic hazard estimates in the CEUS be examined under the GIP. GI... initial screening analysis for GI-199 suggested that estimates of the seismic hazard for some currently...

  3. VizieR Online Data Catalog: Speckle interferometry at USNO. XX. (Hartkopf+, 2015)

    NASA Astrophysics Data System (ADS)

    Hartkopf, W. I.; Mason, B. D.

    2016-02-01

    This is the 20th in a series of papers from the U.S. Naval Observatory's speckle interferometry program, presenting results of observations obtained at the USNO 26inch telescope in Washington, DC. >From 2013 January 4 through 2014 December 18, the 26inch telescope was used on 135 of 451 scheduled nights. (6 data files).

  4. [Biennial Survey of Education, 1926-1928. Bulletin, 1930, No. 16. Chapter I - Chapter XX

    ERIC Educational Resources Information Center

    Office of Education, United States Department of the Interior, 1930

    1930-01-01

    This document contains the first twenty chapters of the Biennial Survey of Education document, covering the years 1926-1928. The following chapters are included in this document: (1) Higher education (Arthur J. Klein); (2) Medical education (N. P. Colwell); (3) Legal education (Alfred Z. Reed); (4) Significant movements in city school systems (W.…

  5. 76 FR 2924 - Proposed Generic Communications; Draft NRC Regulatory Issue Summary 2011-XX; Adequacy of Station...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-18

    ...) electrical safety buses and expectations for voltage calculations for the plant offsite/ onsite electric... Electrical grid events at the Millstone Station, in July of 1976, have shown that when the Class 1E buses are... buses. This condition did not meet the staff position described in BTP PSB-1 and the electrical scheme...

  6. OSMEAN - OSCULATING/MEAN CLASSICAL ORBIT ELEMENTS CONVERSION (HP9000/7XX VERSION)

    NASA Technical Reports Server (NTRS)

    Guinn, J. R.

    1994-01-01

    OSMEAN is a sophisticated FORTRAN algorithm that converts between osculating and mean classical orbit elements. Mean orbit elements are advantageous for trajectory design and maneuver planning since they can be propagated very quickly; however, mean elements cannot describe the exact orbit at any given time. Osculating elements will enable the engineer to give an exact description of an orbit; however, computation costs are significantly higher due to the numerical integration procedure required for propagation. By calculating accurate conversions between osculating and mean orbit elements, OSMEAN allows the engineer to exploit the advantages of each approach for the design and planning of orbital trajectories and maneuver planning. OSMEAN is capable of converting mean elements to osculating elements or vice versa. The conversion is based on modelling of all first order aspherical and lunar-solar gravitation perturbations as well as a second-order aspherical term based on the second degree central body zonal perturbation. OSMEAN is written in FORTRAN 77 for HP 9000 series computers running HP-UX (NPO-18796) and DEC VAX series computers running VMS (NPO-18741). The HP version requires 388K of RAM for execution and the DEC VAX version requires 254K of RAM for execution. Sample input and output are listed in the documentation. Sample input is also provided on the distribution medium. The standard distribution medium for the HP 9000 series version is a .25 inch streaming magnetic IOTAMAT tape cartridge in UNIX tar format. It is also available on a .25 inch streaming magnetic tape cartridge in UNIX tar format or on a 3.5 inch diskette in UNIX tar format. The standard distribution medium for the DEC VAX version is a 1600 BPI 9-track magnetic tape in DEC VAX BACKUP format. It is also available on a TK50 tape cartridge in DEC VAX BACKUP format. OSMEAN was developed on a VAX 6410 in 1989, and was ported to the HP 9000 series platform in 1991. It is a copyrighted work with all copyright vested in NASA.

  7. Tips for a physician in getting the right job, Part XX: more comments on employment contracts.

    PubMed

    Harolds, Jay A

    2015-03-01

    This article discusses a variety of important employment contract issues. This includes remuneration, fringe benefits, and time off. It also includes dispute resolution and the protection of assets and information. Several types of restrictive covenants are also discussed. This information should be useful to job seekers attempting to understand contracts. However, all employment contracts should be discussed with the job seeker's attorney before signing it.

  8. OATYC Journal, Volume XX, Numbers 1-2, Fall 1995-Spring 1996.

    ERIC Educational Resources Information Center

    Houston, Linda, Ed.

    1996-01-01

    Published by the Ohio Association of Two Year Colleges, this journal provides a medium for sharing concepts, methods, and findings relevant to the classroom and an open forum for the discussion and review of problems. This volume consists of the fall 1995 and spring 1996 issues and provides the following articles: (1) "FOCUS: OMI College of…

  9. 78 FR 15406 - Proposed Collection; Comment Request for Revenue Procedure 2013-XX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-11

    ... information technology; and (e) estimates of capital ] or start-up costs and costs of operation, maintenance... submitted for renewal purposes only. Type of Review: Extension of a currently approved collection. Affected...

  10. ExoMol molecular line lists - XX. A comprehensive line list for H3+

    NASA Astrophysics Data System (ADS)

    Mizus, Irina I.; Alijah, Alexander; Zobov, Nikolai F.; Lodi, Lorenzo; Kyuberis, Aleksandra A.; Yurchenko, Sergei N.; Tennyson, Jonathan; Polyansky, Oleg L.

    2017-06-01

    H_3^+ is a ubiquitous and important astronomical species whose spectrum has been observed in the interstellar medium, planets and tentatively in the remnants of supernova SN1897a. Its role as a cooler is important for gas giant planets and exoplanets, and possibly the early Universe. All this makes the spectral properties, cooling function and partition function of H_3^+ key parameters for astronomical models and analysis. A new high-accuracy, very extensive line list for H_3^+ called MiZATeP was computed as part of the ExoMol project alongside a temperature-dependent cooling function and partition function as well as lifetimes for excited states. These data are made available in electronic form as supplementary data to this article and at www.exomol.com.

  11. A Dynamic Computer Model to Examine Selected Effects of 304XX Career Field Consolidation.

    DTIC Science & Technology

    1982-09-01

    Models Career Area Rotation Model (CAROM) CAROM is an existing Air Force personnel model developed for the Air Force Human Resources ...the McIntyre model is essentially a listing of AFSCs and their perform- ance on the three criteria (1:p.1-2). Thus, management 0 personnel can...fluid ongoing process of such management areas as personnel assignment or rotation processes. The dynamic treatment of time allows the model to more

  12. Planck early results. XX. New light on anomalous microwave emission from spinning dust grains

    NASA Astrophysics Data System (ADS)

    Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Arnaud, M.; Ashdown, M.; Aumont, J.; Baccigalupi, C.; Balbi, A.; Banday, A. J.; Barreiro, R. B.; Bartlett, J. G.; Battaner, E.; Benabed, K.; Benoît, A.; Bernard, J.-P.; Bersanelli, M.; Bhatia, R.; Bock, J. J.; Bonaldi, A.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Boulanger, F.; Bucher, M.; Burigana, C.; Cabella, P.; Cappellini, B.; Cardoso, J.-F.; Casassus, S.; Catalano, A.; Cayón, L.; Challinor, A.; Chamballu, A.; Chary, R.-R.; Chen, X.; Chiang, L.-Y.; Chiang, C.; Christensen, P. R.; Clements, D. L.; Colombi, S.; Couchot, F.; Coulais, A.; Crill, B. P.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; de Gasperis, G.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Delouis, J.-M.; Dickinson, C.; Donzelli, S.; Doré, O.; Dörl, U.; Douspis, M.; Dupac, X.; Efstathiou, G.; Enßlin, T. A.; Eriksen, H. K.; Finelli, F.; Forni, O.; Frailis, M.; Franceschi, E.; Galeotta, S.; Ganga, K.; Génova-Santos, R. T.; Giard, M.; Giardino, G.; Giraud-Héraud, Y.; González-Nuevo, J.; Górski, K. M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Hansen, F. K.; Harrison, D.; Helou, G.; Henrot-Versillé, S.; Herranz, D.; Hildebrandt, S. R.; Hivon, E.; Hobson, M.; Holmes, W. A.; Hovest, W.; Hoyland, R. J.; Huffenberger, K. M.; Jaffe, T. R.; Jaffe, A. H.; Jones, W. C.; Juvela, M.; Keihänen, E.; Keskitalo, R.; Kisner, T. S.; Kneissl, R.; Knox, L.; Kurki-Suonio, H.; Lagache, G.; Lähteenmäki, A.; Lamarre, J.-M.; Lasenby, A.; Laureijs, R. J.; Lawrence, C. R.; Leach, S.; Leonardi, R.; Lilje, P. B.; Linden-Vørnle, M.; López-Caniego, M.; Lubin, P. M.; Macías-Pérez, J. F.; MacTavish, C. J.; Maffei, B.; Maino, D.; Mandolesi, N.; Mann, R.; Maris, M.; Marshall, D. J.; Martínez-González, E.; Masi, S.; Matarrese, S.; Matthai, F.; Mazzotta, P.; McGehee, P.; Meinhold, P. R.; Melchiorri, A.; Mendes, L.; Mennella, A.; Mitra, S.; Miville-Deschênes, M.-A.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Munshi, D.; Murphy, A.; Naselsky, P.; Natoli, P.; Netterfield, C. B.; Nørgaard-Nielsen, H. U.; Noviello, F.; Novikov, D.; Novikov, I.; O'Dwyer, I. J.; Osborne, S.; Pajot, F.; Paladini, R.; Partridge, B.; Pasian, F.; Patanchon, G.; Pearson, T. J.; Peel, M.; Perdereau, O.; Perotto, L.; Perrotta, F.; Piacentini, F.; Piat, M.; Plaszczynski, S.; Platania, P.; Pointecouteau, E.; Polenta, G.; Ponthieu, N.; Poutanen, T.; Prézeau, G.; Procopio, P.; Prunet, S.; Puget, J.-L.; Reach, W. T.; Rebolo, R.; Reich, W.; Reinecke, M.; Renault, C.; Ricciardi, S.; Riller, T.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Rowan-Robinson, M.; Rubiño-Martín, J. A.; Rusholme, B.; Sandri, M.; Santos, D.; Savini, G.; Scott, D.; Seiffert, M. D.; Shellard, P.; Smoot, G. F.; Starck, J.-L.; Stivoli, F.; Stolyarov, V.; Stompor, R.; Sudiwala, R.; Sygnet, J.-F.; Tauber, J. A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Torre, J.-P.; Tristram, M.; Tuovinen, J.; Umana, G.; Valenziano, L.; Varis, J.; Verstraete, L.; Vielva, P.; Villa, F.; Vittorio, N.; Wade, L. A.; Wandelt, B. D.; Watson, R.; Wilkinson, A.; Ysard, N.; Yvon, D.; Zacchei, A.; Zonca, A.

    2011-12-01

    Anomalous microwave emission (AME) has been observed by numerous experiments in the frequency range ~10-60 GHz. Using Planck maps and multi-frequency ancillary data, we have constructed spectra for two known AME regions: the Perseus and ρ Ophiuchi molecular clouds. The spectra are well fitted by a combination of free-free radiation, cosmic microwave background, thermal dust, and electric dipole radiation from small spinning dust grains. The spinning dust spectra are the most precisely measured to date, and show the high frequency side clearly for the first time. The spectra have a peak in the range 20-40 GHz and are detected at high significances of 17.1σ for Perseus and 8.4σ for ρ Ophiuchi. In Perseus, spinning dust in the dense molecular gas can account for most of the AME; the low density atomic gas appears to play a minor role. In ρ Ophiuchi, the ~30 GHz peak is dominated by dense molecular gas, but there is an indication of an extended tail at frequencies 50-100 GHz, which can be accounted for by irradiated low density atomic gas. The dust parameters are consistent with those derived from other measurements. We have also searched the Planck map at 28.5 GHz for candidate AME regions, by subtracting a simple model of the synchrotron, free-free, and thermal dust. We present spectra for two of the candidates; S140 and S235 are bright Hii regions that show evidence for AME, and are well fitted by spinning dust models. Corresponding author: C. Dickinson, Clive.Dickinson@manchester.ac.uk

  13. Historical sources on climate and extreme events before XX century in Calabria (Italy)

    NASA Astrophysics Data System (ADS)

    Aurora Pasqua, Angela; Petrucci, Olga

    2014-05-01

    Damaging Hydrogeological Events (DHEs) are defined as the occurrence of destructive phenomena, such as landslides and floods, triggered by extreme rain events. Due to the huge damage that they can cause to people and properties, DHEs are often described in a wide series of historical sources. The historical series of DHEs that affected a study region can supply useful information about the climatic trend of the area. Moreover, it can reveals temporal and spatial increases in vulnerability affecting sectors where urbanization increased throughout the time. On the other side, it can highlight further vulnerability variations occurred throughout the decades and related to specific defensive measures undertaken (or abandoned) in order to prevent damage caused by either landslides or floods. We present the historical series of catastrophic DHEs which affected a Mediterranean region named Calabria that is located in southern Italy. Data presented came from the database named ASICal (the Italian acronym of historically flooded areas in Calabria) that has been built at the beginning of 2000 at CNR-IRPI of Cosenza and that has been continuously updated since then. Currently, this database includes more than 11,000 records about floods and landslides which have been occurred in Calabria since the XVI century. These data came from different information sources as newspapers, archives of regional and national agencies, scientific and technical reports, on-site surveys reports and so on. ASICal is constantly updated. The updating concerns both current DHEs that every years affect the region, and the results of specific historical research that we regularly perform in order to fill data gaps for older epochs. In this work we present the result of a recent survey carried out in some regional public libraries focusing on the early-mid XIX century. The type of data sources available for the regional framework are described and a sketch of the DHEs trend during the last three centuries is presented. Moreover, a panoramic view of both proxy data and irregularly measured parameters concerning climatic trend of the region obtained from the analyzed historical sources is also shown.

  14. AESOP XX: summary of proceedings. [Gatlinburg, Tennessee, April 24 to 26, 1979

    SciTech Connect

    1980-03-01

    The 20th meeting of the Association for Energy Systems, Operations, and Programming (AESOP) was held in Gatlinburg, Tennessee, on April 24 to 26, 1979. Representatives of DOE Headquarters discussed the effects that new security and privacy regulations will have on automatic data processing operations. The status and future possibilities of the Business Management Information System (BMIS) were also discussed. Then representatives of various DOE offices and contractors presented reports on various topics. This report contains two-page summaries of the papers presented at the meeting. Session topics and titles of papers were as follows: Washington report (New ADP issues; BMIS: the Business Management Information System; Nuclear weapons and the computer); Improving the productivity of the computing analyst/programer (What productivity improvement tools are available; Rocky Flats experience with SDM/70; Albuquerque Operations Office experience with SDM/70; Planning and project management; Minicomputer standards and programer productivity; MRC productivity gains through applications development tools); User viewpoints and expectations of data processing (User perspectives on computer applications; User viewpoints on environmental studies; Planning and implementing a procurement system; Two sides of the DP coin); Data base management (Use of data base systems within DOE; Future trends in data base hardware; Future trends in data base software; Toward automating the data base design process); and Management discussions. Complete versions of three of the papers have already been cited in ERA. These can be located by reference to the entry CONF-790431-- in the Report Number Index. (RWR)

  15. Language XX: What shall it be called and why does it matter?

    PubMed

    Nelson, Nickola Wolf

    2016-06-01

    Terms suggested for unexpected language learning difficulty include specific language impairment, primary language disorder and language learning disability; however, none of them represents the critical element of literacy. Some experts have suggested that debating what to call language disorders is parallel to debating what to call reading disorders and dyslexia. In contrast, it is argued here that reading disorders are language disorders and not separate or parallel. Evidence is presented for quadrant models that explain language disorders and dyslexia along two dimensions-sound/word level (phonological) knowledge and sentence/discourse level (non-phonological) knowledge. Support for these two dimensions comes from factor analysis of a new assessment tool called the Test of Integrated Language and Literacy Skills (TILLS). Two case studies illustrate how a quadrant model can be used to explain patterns of abilities that vary along these two dimensions to parents and teachers. The article concludes with a recommendation to adopt a label that reflects language/literacy commonalities rather than differences, such as language/literacy disorder or specific language/literacy impairment.

  16. Chemically Modified Electrodes. Part XX. Radiofrequency Plasma Polymerization of Vinylferrocene on Glassy Carbon and Platinum Electrodes.

    DTIC Science & Technology

    1980-01-29

    1978) 3222. 3 N. Oyama and F. C. Anson , J. Amer. Chem. Soc., 101 (1979) 739. 4 Symposium on Chemically Modified Electrodes, Extended Abstracts of...T. Hirotsu, J. Polym. Sci., Polym. Chem. Ed., 16 (1978) 229. 24 N. Oyama, A. P. Brown and F. C. Anson , J. Electroanal. Chem., 87 (1978) 435. 25 H...91232 Dr. Fred Saalfeld Mr. John Boyle Chemistry Division Materials Branch Naval Research Laboratory Naval Ship Engineering Center Washington, D.C

  17. Synthesis and characterization of noble metal borides: RuB{sub x}(x > 1)

    SciTech Connect

    Li, Zhifang; Zheng, Dafang; Ding, Zhanhui; Li, Yongfeng; Yao, Bin; Li, Yongsheng; Zhao, Xudong; Yu, Guichuan; Tang, Yang; Zheng, Weitao; Liu, Xiaoyang

    2016-02-15

    Highlights: • Hexagonal RuB{sub 1.1} were synthesized using ruthenium and boron powders as raw materials during ball milling process. • Orthorhombic RuB{sub 2} were synthesized under high pressure (5 GPa) and high temperature (1000 °C) conditions. • Hexagonal Ru{sub 2}B{sub 3} have been synthesized under 5 GPa and 1200 °C. - Abstract: Noble metal borides RuB{sub 1.1}, RuB{sub 2} and Ru{sub 2}B{sub 3} have been synthesized by mechanical alloying and high pressure sintering methods using ruthenium (Ru) and boron (B) powders as raw materials. The crystal structures of borides were characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM). The results shown that only RuB{sub 1.1} with hexagonal crystal structure was synthesized during the ball milling process, the orthorhombic RuB{sub 2} was synthesized under high pressure (5 GPa) and high temperature (1000 °C) conditions, while the hexagonal Ru{sub 2}B{sub 3} can be synthesized under 5 GPa and 1200 °C. The mechanism of synthesis for the ruthenium borides (RuB{sub x}) are discussed in details.

  18. X-Ray Toolkit (XTK) Touch App v. 1.0.x.x

    SciTech Connect

    Garretson, Justin; Hobart, Clinton; Rael, Reymundo; Eldridge, Bryce

    2016-01-20

    Windows 8 App for use in viewing, enhancing, and manipulating x-ray images. Intended for use by state/local government, federal agencies, and military in explosive ordinance disposal (EOD) applications.

  19. Cartography/Geodesy Utilization Field and Geodetic Career Field (AFSs 57XX and 222X0).

    DTIC Science & Technology

    1984-01-01

    include the Geodetic Specialist, DAFSCs 22230, 22250, 22270 , 22290, and 22200. The occupational survey data were collected and analyzed to identify... 22270 , 22290, and 22200 were asked to complete a job inventory. Individuals filled out an identification and background information section and then...RESPONDING DAFSC DAFSC DAFSC 22230 22250 22270 INTERESTING 100 87 88 so-so - 11 6 DULL - 2 6 TABLE 23 AFSC 222X0 UTILIZATION OF TALENTS PERCENT RESPONDING

  20. 76 FR 10072 - Proposed Generic Communications; Draft NRC Regulatory Issue Summary 2011-XX, Adequacy of Station...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-23

    ... Electric Distribution System Voltages; Reopening of Public Comment Period AGENCY: Nuclear Regulatory..., Adequacy of Station Electric Distribution System Voltages, closes on February 17, 2011. The purpose of this... February, 2011. For the Nuclear Regulatory Commission. Roy Mathew, Acting Branch Chief, Electrical...

  1. Disaster Preparedness Utilization Field/Disaster Preparedness Career Ladder, AFSCs 05XX/242X0

    DTIC Science & Technology

    1988-11-01

    jobs. Structure Overview I. BRANCH AND DIVISION CHIEFS (N=176) II . DISASTER PREPAREDNESS SPECIALISTS (N=48) III. INDEPENDENT DISASTER PREPAREDNESS...la V. ) I-- 5- Ii UCI- 1 I- I I4 ICN% 2Z Sq-*W -414LJLe L . ~z2c 2- 00 C% Ci C144No 04 LaWLW ~W LJ Cj 9 1-0CD2 JCm~ L6f ccc0c0iLa s y c LuJ W La Lai%:N...IC.)aCa Wa~I .Z aZ EU WZ12EU LAJ) L. CD e (V C) 0cI- c-. OW<CD "in-~I-lw (5 - CD W- Li) CU Q I- t.4 o~ ( =Ij - LAS obD .L U) ’E Oru 4At Lf U ~ 03 40 CC

  2. Gas tungsten arc and shielded metal arc welding of AISI 41XX steels. Welding procedure specification

    SciTech Connect

    Wodtke, C.H.; Frizzell, D.R.

    1985-08-01

    Procedure WPS-127 is qualified under Section IX of the ASME Boiler and Pressure Vessel Code for gas tungsten arc and shielded metal arc welding of AISI 4130 and 4142 steels (ASTM A519) (P-No: None), 0.438-in. wall pipe; filler metal is AMS 6457, Class 4130 MC (F-, A-No; None) (GTAW) and E8018-B2L (F-4, A-3) (GMAW); shielding gas is argon (GTAW).

  3. Analysis of The Xx Century Effusive Activity At Mount Etna To Assess The Potential Effusive Hazard.

    NASA Astrophysics Data System (ADS)

    Andronico, D.; Lodato, L.; Neri, M.

    We examined older documents and publications together with more recent and de- tailed reports related to the 20th century effusive activity (terminal and flank eruptions) at Mt. Etna, with the primary objective of creating a single data-base of volcanologi- cal data, at present lacking in the literature. The restitution in digital form of the maps of the lava fields allowed to measure, with great precision compared with previous estimations, the area and length of every lava flow, allowing improved estimates of volumes and effusive rates. The quantity and the quality of the collected bibliographic information of the studied eruptions improve progressively from the beginning of the century up to the present, and can be considered complete for the flank activity. The data of each single eruption have been inserted into a relational database, that pro- vides both ease of use and the potential of upgrading with information from new or more ancient eruptions. By examining the collected data (e.g. maximum length of lava flows, altitude reached, eruption duration) we obtained some useful relationships, that allowed us to characterise some eruption typologies at Etna. The improvement of the volcanic data related to the effusive activity of the last century represents an impor- tant contribution in terms of volcanic hazard, suggesting for example the areas most at risk by opening of eruptive fractures and lava covering. Statistical observations can be a useful contribution to the planning required by civil defense in a strongly urban- ized area, such as the etnean one; assessment hazard, in particular, should be focused particularly on the southeastern foot of the volcanic belt, in which the volcanic risk in- creases due to the presence of several populated centers that amount to approximately 500.000 people.

  4. 76 FR 40282 - Proposed Generic Communications; Draft NRC Regulatory Issue Summary 2011-XX; NRC Regulation of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-08

    ... use in traditional military operations. This RIS resolves an existing ambiguity by clarifying that... continue their existing role under CERCLA for these sites. However, NRC would reserve the option...

  5. Stereotactic radiosurgery XX: ocular neuromyotonia in association with gamma knife radiosurgery

    PubMed Central

    McQuillan, Joe; Plowman, P Nicholas; MacDougall, Niall; Blackburn, Philip; Sabin, H Ian; Ali, Nadeem; Drake, William M

    2015-01-01

    Summary We report three patients who developed symptoms and signs of ocular neuromyotonia (ONM) 3–6 months after receiving gamma knife radiosurgery (GKS) for functioning pituitary tumours. All three patients were complex, requiring multi-modality therapy and all had received prior external irradiation to the sellar region. Although direct causality cannot be attributed, the timing of the development of the symptoms would suggest that the GKS played a contributory role in the development of this rare problem, which we suggest clinicians should be aware of as a potential complication. Learning points GKS can cause ONM, presenting as intermittent diplopia.ONM can occur quite rapidly after treatment with GKS.Treatment with carbamazepine is effective and improve patient's quality of life. PMID:26294961

  6. 8111/8116 Security Police Staff Officers 8121/8124 Security Police Officers AFSC: 81XX

    DTIC Science & Technology

    1992-02-01

    4. 04 S -4C S. 4.4 .4.C At Oq- U o C u..444 a4 x 01 C C -0 - P1 .A.- !4 4q0 L A. aU LU I a4 a C0 A.XV a L 0 1 -U S.0.0 4 CL A40 0NC 4.a SC C a E43 C~ z...L - - R~ . ( *U # ACCa .4 % 40 a - 4- 1 4 4-L 0 *-46.40 50 a .40C CL 0 Ŕ 1 0. 0 OUUCC>CU.U0C4-LSa LC .CaC CW~ift-4C .4,4f L .4 -S(( a-..CA a COC *-. 4...Ni .C! o ~ a -N 4 Ř’,-4 .C.M-M4"-40.M.𔃾 M M -4 M4. .4 P1 M M4 .4.M4.󈧒 14 C L me a > 0. IL 0 c C. CD𔃺A1 a 4’L 0. C%-’ti "~nn =O~ 0N N? - 0W 0% 14

  7. 77 FR 12089 - Proposed Generic Communication; Regulatory Issue Summary 2012-XX: Developing Inservice Testing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-28

    ...-related components and systems shall be designed to permit appropriate periodic inspection of important... NRC-2012-0048. NRC's Agencywide Documents Access and Management System (ADAMS): You may access... license (COL) or standard design certification for a nuclear power plant under the provisions of Title 10...

  8. The Herschel Virgo Cluster Survey. XX. Dust and gas in the foreground Galactic cirrus

    NASA Astrophysics Data System (ADS)

    Bianchi, S.; Giovanardi, C.; Smith, M. W. L.; Fritz, J.; Davies, J. I.; Haynes, M. P.; Giovanelli, R.; Baes, M.; Bocchio, M.; Boissier, S.; Boquien, M.; Boselli, A.; Casasola, V.; Clark, C. J. R.; De Looze, I.; di Serego Alighieri, S.; Grossi, M.; Jones, A. P.; Hughes, T. M.; Hunt, L. K.; Madden, S.; Magrini, L.; Pappalardo, C.; Ysard, N.; Zibetti, S.

    2017-01-01

    We study the correlation between far-infrared/submm dust emission and atomic gas column density in order to derive the properties of the high Galactic latitude, low density, Milky Way cirrus in the foreground of the Virgo cluster of galaxies. Dust emission maps from 60 to 850 μm are obtained from observations with the Spectral and Photometric Imaging Receiver (SPIRE) and carried out within the Herschel Virgo Cluster Survey (HeViCS); these are complemented by IRAS and Planck maps. Data from the Arecibo legacy Fast ALFA Survey is used to derive atomic gas column densities for two broad velocity components: low and intermediate velocity clouds. Dust emissivities are derived for each gas component and each far-infrared/submm band. For the low velocity clouds, we measure an average emissivity ɛLVCν = (0.79 ± 0.08) × 10-20 MJy sr-1 cm2 at 250 μm. After fitting a modified blackbody to the available bands, we estimated a dust absorption cross section of τLVCν/NH i = (0.49 ± 0.13) × 10-25 cm2 H-1 at 250 μm (with dust temperature T = 20.4 ± 1.5 K and spectral index β = 1.53 ± 0.17). The results are in excellent agreement with those obtained by Planck over a much larger coverage of the high Galactic latitude cirrus (50% of the sky versus 0.2% in our work). For dust associated with intermediate velocity gas, we confirm earlier Planck results and find a higher temperature and lower emissivity and cross section. After subtracting the modeled components, we find regions at scales smaller than 20' in which the residuals deviate significantly from the average scatter, which is dominated by cosmic infrared background. These large residuals are most likely due to local variations in the cirrus dust properties or to high-latitude molecular clouds with average NH2 ≲ 1020 cm-2. We find no conclusive evidence for intracluster dust emission in Virgo. Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA.Final reduced data (FITS) are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/597/A130

  9. Changing Security Threats: What Africans Must Accommodate in the XX1st Century.

    DTIC Science & Technology

    1999-03-30

    players are necessary to stem the tide of deterioration. An aggressive strategy towards improved socio-economic conditions in the short term and regional ... development in the long term is critical to ensure Sub-Saharan Africa becomes part of and play a participating role in the global economic community.

  10. THE ANGLO-AUSTRALIAN PLANET SEARCH. XX. A SOLITARY ICE-GIANT PLANET ORBITING HD 102365

    SciTech Connect

    Tinney, C. G.; Wittenmyer, Robert A.; Bailey, Jeremy; Butler, R. Paul; Jones, Hugh R. A.; O'Toole, Simon; Carter, Brad D.

    2011-02-01

    We present 12 years of precision Doppler data for the very nearby G3 star HD 102365, which reveals the presence of a Neptune-like planet with a 16.0 M{sub Earth} minimum mass in a 122.1 day orbit. Very few 'Super Earth' planets have been discovered to date in orbits this large and those that have been found reside in multiple systems of between three and six planets. HD 102365 b, in contrast, appears to orbit its star in splendid isolation. Analysis of the residuals to our Keplerian fit for HD 102365 b indicates that there are no other planets with minimum mass above 0.3 M{sub Jup} orbiting within 5 AU and no other 'Super Earths' more massive than 10 M{sub Earth} orbiting at periods shorter than 50 days. At periods of less than 20 days these limits drop to as low as 6 M{sub Earth}. There are now 32 exoplanets known with minimum mass below 20 M{sub Earth}, and interestingly the period distributions of these low-mass planets seem to be similar whether they orbit M-, K-, or G-type dwarfs.

  11. [Clinical research XX. From clinical judgment to multiple logistic regression model].

    PubMed

    Berea-Baltierra, Ricardo; Rivas-Ruiz, Rodolfo; Pérez-Rodríguez, Marcela; Palacios-Cruz, Lino; Moreno, Jorge; Talavera, Juan O

    2014-01-01

    The complexity of the causality phenomenon in clinical practice implies that the result of a maneuver is not solely caused by the maneuver, but by the interaction among the maneuver and other baseline factors or variables occurring during the maneuver. This requires methodological designs that allow the evaluation of these variables. When the outcome is a binary variable, we use the multiple logistic regression model (MLRM). This multivariate model is useful when we want to predict or explain, adjusting due to the effect of several risk factors, the effect of a maneuver or exposition over the outcome. In order to perform an MLRM, the outcome or dependent variable must be a binary variable and both categories must mutually exclude each other (i.e. live/death, healthy/ill); on the other hand, independent variables or risk factors may be either qualitative or quantitative. The effect measure obtained from this model is the odds ratio (OR) with 95 % confidence intervals (CI), from which we can estimate the proportion of the outcome's variability explained through the risk factors. For these reasons, the MLRM is used in clinical research, since one of the main objectives in clinical practice comprises the ability to predict or explain an event where different risk or prognostic factors are taken into account.

  12. Changing Climate And Timberline Dynamics Of The Carpathians During XX Century

    NASA Astrophysics Data System (ADS)

    Martazinova, V.; Weisberg, P.; Maderych, V.; Ivanova, E.; Savchuk, S.; Shandra, A.

    2010-12-01

    In this investigation weather changes over the Carpathian Mountains during the 20th ct. and their influence on timberline changes are analyzed. Forest cover at timberline is ecologically and societally important because it decreases probability of avalanche occurrence, debris flows, and may decrease negative consequences of floods. First of all, changes in large-scale atmospheric circulation and the response of regional circulation over Carpathian territory were considered. Changes in temperature and precipitation were analyzed on a decadal basis for the 20th ct. and the first decade of the 21st ct. over three regions (West , East, and South Carpathians). The largest changes up to the 21st ct. are during the winter. In the West Carpathians, temperature has increased greatly during the winter, significantly less during the summer, and minimally during transitional seasons. Precipitation increased during the winter and summer, to a smaller extent in the fall, and decreased during spring. In the East Carpathians the increase of temperature is more pronounced in the winter and in the beginning of the 21st ct. exceeds mid-20th century by 1°C. Precipitation noticeably increased in the 1970’s and, until the beginning of the 21st ct., the South slope retained this level, whereas the North experienced an instability in precipitation. In the South Carpathians temperature at the beginning of the 21st ct. exceeds that of the mid-20th ct. by 1°C. The level of winter precipitation at the end of the last decade is similar to its level at the beginning of the study period, summer precipitation is less, and spring precipitation trends are geographically variable, risingon the South-western slopes and falling on the South-Eastern ones. Timberline changes between 1880 and 2000 were analyzed by comparing military maps of the Austro-Hungarian Empire and contemporary Landsat imagery. The whole region experienced a decline in forest cover from 73.2%, to 70.6%. Forest cover increased by nearly 7% in the West Carpathians by only 0,5% in the Ukrainian Carpathians, and decreased in the North and South Romanian Carpathians (-6,3% and -1,9%, respectively). Regional variation in forest cover change at timberline can be attributed to sociopolitical differences in land use practices over time, including logging, sheep and cattle pastures, and subsequent abandonment of pastures. A peak of afforestation occured at different elevations in the different regions, ranging from 1450 m to 1700 m. Most afforestation is associated with an expansion of coniferous, largely Picea-dominated forests, More than 50% of afforestation was associated with pasture abandonment, whereas 68% of deforestation was associated with human-caused pasture expansion. Deforestation exceeded afforestation at the highest timberline elevations, with the pattern reversed at lower elevations. Overall, the Carpathians timberline represents a complex mosaic of forests that have variously expanded and declined in extent and elevational range, highlighting the complex nature of mountain forest responses to climate change in the context of rapidly evolving land use practices.

  13. Low-cost/high-efficiency lasers for medical applications in the 14XX-nm regime

    NASA Astrophysics Data System (ADS)

    Callahan, J. J.; McIntyre, E.; Rafferty, C.; Yanushefski, L.; Bean, D. M.

    2011-03-01

    Laser therapy is becoming an increasingly popular method of treating numerous dermatological conditions. The widespread use of these devices is often limited by the cost and size. Low cost, portable lasers would expand the laser market further into homes, general practitioners, dermatologists, plastic surgeons, and 3rd world countries. There are numerous light devices currently on the market for hair removal and growth, acne reduction, and wrinkles. These devices are varied, from LEDs to intense pulsed light (IPL) to lasers. One particular disease is leishmaniasis, caused by a parasite carried by sand flies, most often occurring in third world countries. While there are drug therapies available, they sometimes require hospitalization for several days and are very expensive. An RF device has been FDA approved for treatment of leishmaniasis, but costs about $20,000 which is too expensive for widespread use. Since the method is heating the lesion, the same affect could be achieved using an infrared laser. Diode lasers have the capability to be produced in mass quantity for low costs, as shown by the ubiquity of diode lasers in the telecom industry and household appliances. Unfortunately, many diode lasers suffer from poor efficiency, particularly in wavelengths for dermatology. Advances are being made to improve wall plug efficiency of lasers to reduce waste heat and increase output power. In this paper, those efforts being made to develop manufacturing partners to lower the cost while increasing the production volume of long wavelength lasers will be discussed along with performance data and clinical results.

  14. Properties and nature of Be stars. XX. Binary nature and orbital elements of gamma Cas

    NASA Astrophysics Data System (ADS)

    Harmanec, P.; Habuda, P.; Štefl, S.; Hadrava, P.; Korčáková, D.; Koubský, P.; Krtička, J.; Kubát, J.; Škoda, P.; Šlechta, M.; Wolf, M.

    2000-12-01

    An analysis of accurate radial velocities (RVs) of the Be star gamma Cas from 295 Reticon spectrograms secured between October 1993 and May 2000 allowed us to prewhiten the RVs for the long-term changes and to obtain the first orbital RV curve of this star. The orbital period is 203 Delta59 and the orbit has an eccentricity of 0.26. The orbital motion is detectable even in the published velocities, based on photographic spectra. This implies that gamma Cas is a primary component of a spectroscopic binary. The secondary has a mass of about 1 \\ms, appropriate for a white dwarf or a neutron star, but it could also be a normal late-type dwarf. The ultimate solution of the dispute whether the observed X-ray emission is associated with the secondary or with the primary will need further dedicated studies.

  15. A Process Control System for Hewlett-Packard Series 21XX Computers.

    DTIC Science & Technology

    1980-08-01

    EXPERIMENT 0034 ILOG(3)no 0035 1LOG(4)u’) 0036 1Pa2 003? CALL LOGDA 0038 ISSFLŔ 0039 ILAST*O 0040 ISUPER =O 0041 HS-IPRM(4 0042 105 IFLGuO 0043 I ST=NS...0044 IF(:STAB(14,IST) GT.O)CALL INITL 0045 IF( ISSFL.GT.O)GO TO 110 0046 CALL IHSCB( IND) 0047 110 ISUPER =ILAST 0048 IF(ISUPER.LE.0)GO TO 111 0049 IF...ISCB(4,I3UPER).HE.INnD)ISCB(4, ISUPER )=IND 0050 111 ILAST=INDC 0051 IF( ISTAB( 13,1ST).EQ 0 )GO TO 120 0052 CALL INSCB( INDSS) B-23 0053 C SET UP COUNT

  16. Quality of life of patients with 46,XX and 46,XY disorders of sex development.

    PubMed

    Amaral, Rita Cassia; Inacio, Marlene; Brito, Vinicius N; Bachega, Tania A S S; Domenice, Sorahia; Arnhold, Ivo J P; Madureira, Guiomar; Gomes, Larissa; Costa, Elaine M F; Mendonca, Berenice B

    2015-02-01

    Disorders of sex development (DSD) result from abnormalities in the complex process of sex determination and differentiation. An important consideration to guide the assignment of social sex in newborns with ambiguous genitalia is the quality of life (QoL) of these patients in adulthood. The rarity of most DSD conditions makes it difficult to conduct a long-term follow-up of affected patients through adulthood. This review of papers on the QoL of DSD patients evaluated in developing and developed countries by qualitative and quantitative instruments revealed a large spectrum of QoL, ranging from very poor to similar to, or even better than, the normal population. A more adequate QoL was found in patients from tertiary centres, indicating that the medical care of DSD patients should be multidisciplinary and carried out by specialized teams.

  17. Hydrosweep Measurements During the Expedition ARK XX-2 to Lena Trough and Western Gakkel Ridge

    NASA Astrophysics Data System (ADS)

    Gauger, S.; Kohls, T.; Roeber, S.; Snow, J.

    2004-12-01

    The region of Lena Trough and Western Gakkel Ridge in the Arctic Ocean was the object of an expedition in the summer of 2004. This region is of particular geoscientific interest because of its extremely slow spreading rates and the variety of morphologic forms that are produced in this tectonic environment. Therefore, the multibeam measurement system was of particular importance to the scientific goals of the cruise. The main characteristic of the Hydrosweep DS-2 deep-water sounding system aboard RV Polarstern is the 90° or 120° coverage angle in which the seafloor is depicted with 59 specific values for water depths perpendicular to the ship's long axis. The accuracy of the measurement is approx. 1% of water depth, the frequency of the acoustic signal is 15.5 kHz. The refraction of the sonar beams was corrected by automatic crossfan calibration. By regular transmission and measurement of a sweep profile in the ship's longitudinal direction and comparison of the slant beams with the vertical beam, the mean sound velocity over the vertical water column is determined and is used for the depth computation. The data collected include depth, sidescan (2048 values per scan), and backscatter information on each of the 59 beams. During this cruise, the Lena Trough was surveyed systematically for the first time by a multibeam sonar system. The recorded area has an expanse of approx. 100000 km2 and connects previously mapped areas of the Eurasian - North-American plate boundary between Fram Strait and Gakkel Ridge. The region of Western Gakkel Ridge, mapped in 2001 (AMOR-Expedition) by RV Polarstern and USCGC Healy (USA), was extended by two more profiles (each 220 km long) along the ridge. In order to produce working maps for the expedition, the multibeam sonar data were gridded with a spacing of 50 m, producing plots with various contour line intervals. For further morphological interpretation of Lena Trough and Gakkel Ridge slope magnitude maps, slope direction maps and two-dimensional slope histograms were produced. They show clearly the predominant slope direction and are helpful in distinction between sediment basins, volcanos and ridge flanks.

  18. Assessment of oceanity and continentality conditions of the XX Century in the Iberian Peninsula

    NASA Astrophysics Data System (ADS)

    Andrade, Cristina; Corte-Real, João

    2016-04-01

    The oceanity and continentality conditions clearly influence the climate of a region. Seeking at understanding these influences on the Iberian Peninsula climate, the spatial distributions of air temperature, precipitation and five climatic indices are analysed in the period between 1901 and 2012 and in three sub-periods (1901-40, 1941-80 and 1981-2012). This study aims at investigating the Xerothermic index of Gaussen and the continental and oceanic characteristics of the Iberian climate by using Conrad-Pollak and Johansson Continentality Indices, as well as Kerner and Marsz Oceanity Indices. Gridded air temperature and precipitation datasets are used on a monthly basis. Results reveal hyper-oceanic (maritime) characteristics in the northernmost portion of Iberia, continental in the inner region comprising Extremadura, Castile-La Mancha and Andalusia, and maritime characteristics in between. It is worth mentioning that within these regions the maritime (continental) characteristics become weaker (stronger) between 1981 and 2012. Statistically significant linear trends show an increase in both temperature (2-4°C) and on continental influences in the northwestern and southeastern regions of Iberia for the entire period. Statistically significant correlations are also found between the Johansson Continentality Index and both Conrad-Pollak and Marsz Oceanity Indices at a 95% confidence level, revealing a good agreement of results among these indices. This work is supported by: European Investment Funds by FEDER/COMPETE/POCI-Operational Competitiveness and Internationalization Programme, under Project POCI-01-0145-FEDER-006958 and National Funds by FCT - Portuguese Foundation for Science and Technology, under the project UID/AGR/04033.

  19. Tabanidae (Diptera) of Amazônia XX. description of Tabanus pseudonebulosus n.sp.

    PubMed

    Gorayeb, Inocêncio de Sousa; de Barros, Antonio Thadeu Medeiros

    2006-03-01

    Tabanus pseudonebulosus, new species, is described based on 217 female specimens and 5 males collected in Venezuela (Guarico, Aguaio, Santa Elena, and Palmarito) and in Brazil (Parcí: Santana do Araguaia, Serra das Andorinhas in São Geraldo do Araguaia, Serra Norte Carajás and Gorotire; Amazonas: Canutama; Mato Grosso do Sul: Corumbá), mostly in open vegetation, scrub forest and in rocky environments. Observed intraspecific variation in the specimens is presented and related to collection localities, and morphological differences are diagnosed in relation to the similar species Tabanus nebulosus DeGeer 1776 and T. importunus Wiedemann 1828. Morphometrical data and indices for specimens in different localities are provided. Drawings and photo of the new species are presented.

  20. Follow-Up Study of 1990 Nursing Graduates. Volume XX, No. 10.

    ERIC Educational Resources Information Center

    Lucas, J.; Meltesen, C.

    In 1990, a follow-up study of nursing program graduates was conducted at William Rainey Harper College (WRHC) in Palatine, Illinois, to examine their employment patterns, further education plans, and evaluate particular aspects of their WRHC experience. All 98 nursing students who earned 48 credit hours in 1990 were mailed questionnaires 1 year…

  1. [Concept and history of public health in Mexico (XVIII to XX century)].

    PubMed

    Fierros Hernández, Arturo

    2014-01-01

    This paper is a brief history of public health. I review the concept of public health and its origins in the West, and also analyze the input of politics in the Mexican health system through the government of Porfirio Diaz.

  2. AUTOMOTIVE DIESEL MAINTENANCE 1. UNIT XX, CUMMINS DIESEL ENGINE, MAINTENANCE SUMMARY.

    ERIC Educational Resources Information Center

    Minnesota State Dept. of Education, St. Paul. Div. of Vocational and Technical Education.

    THIS MODULE OF A 30-MODULE COURSE IS DESIGNED TO PROVIDE A SUMMARY OF THE REASONS AND PROCEDURES FOR DIESEL ENGINE MAINTENANCE. TOPICS ARE WHAT ENGINE BREAK-IN MEANS, ENGINE BREAK-IN, TORQUING BEARINGS (TEMPLATE METHOD), AND THE NEED FOR MAINTENANCE. THE MODULE CONSISTS OF A SELF-INSTRUCTIONAL BRANCH PROGRAMED TRAINING FILM "CUMMINS DIESEL ENGINE…

  3. A Critical Analysis of the U.S. Marine Corps 04XX Logistics Community

    DTIC Science & Technology

    2013-04-15

    principle end item (PEI) rotation program requirement. 15. Facilitate Performance Based Logistics (PBL) requirements. 0411-OPS-2402: Monitor the...CLEARA NCE REQUES T FOR PUBLIC RELEA SE OF DEPARTMENT OF DEFENSE INFORMAT ION (Soo fnsrrucTions on back .) (This form is To bo used in requesTing...TION DATA ( Dato . Ptaco. Event) Submitted to higher headquarters for infomL1tion purposes on 2 May 2013. This request is made prior to submission to the

  4. Follow-Up Study of 1990 Nursing Graduates. Volume XX, No. 10.

    ERIC Educational Resources Information Center

    Lucas, J.; Meltesen, C.

    In 1990, a follow-up study of nursing program graduates was conducted at William Rainey Harper College (WRHC) in Palatine, Illinois, to examine their employment patterns, further education plans, and evaluate particular aspects of their WRHC experience. All 98 nursing students who earned 48 credit hours in 1990 were mailed questionnaires 1 year…

  5. Training Extract AFSC 51XX Computer Systems Officer AFPT 90-51X-468.

    DTIC Science & Technology

    1983-06-01

    AGREENEATS .16 1.1 2.2 .0 .0 8 BA COORDINATE PAYING OF FOREIGN NATIONALS ITN PAT OFFCIALS .|6 .1 .0 2.0 .0 C 77 APPROVE OR 0SAPPROVE COURSE MATERIALS SUE...m 421 CERTIFY DESTRUCTION OF CLASSIFIED MATERIALS 1.0c 1I. 8 Z0.3 18.9 21.8 7.? H HA0 REPORT DISCLOSURE OF CLASSIFIED OR RESTRICTED...PROGRAM MODIFICATION REQUESTS OR COMPUTER 2.15 1 Ao.3 ZO. 8 24,3 29.1 7,9 SUPPORT REQUESTS H 491 STORE OR SAFEGUARD CLASSIFIED MATERIAL 2.11 23.9 31.7

  6. Military Specification for Type 10XX Powder-Forged Weapon Components.

    DTIC Science & Technology

    1985-10-14

    ASTM E8 - Tension Testing of Metallic Materials ASTM E18 - Rockwell Hardness and Rockwell Superficial Hardness of Metallic Materials ASTM E23 - Notched...measurements shall be determined in accordance with ASTM E18 on sectioned forgings. All hardness values shall be recorded to the nearest 0.2. t 4.5.5.2...machined into standard Jominy end-quench specimens per ASTM A2bb. Blanks, 0.42b" x U.425" x 3" (11 mm x 11 mm x 76 mm), for tensile and impact specimens

  7. Gonadal dysgenesis, Turner syndrome with 46,XX,del(18p)3

    SciTech Connect

    Telvi, L.; Ion, R.; Bernheim, A.

    1994-09-01

    The authors report a case of a female infant with gonadal dysgenesis, clinical features of Turner syndrome and a de novo del(18p). The factors controlling gonadal dysgenesis and Turner syndrome are unknown to date. The genes involved could be located not only on X chromosome but also on autosomes. The present case suggests that one of these genes is situated on the short arm of chromosome 18. We conclude that patients with del(18p) syndrome should be evaluated for gonadal dysgenesis.

  8. The Next Generation Virgo Cluster Survey. XX. RedGOLD Background Galaxy Cluster Detections

    NASA Astrophysics Data System (ADS)

    Licitra, Rossella; Mei, Simona; Raichoor, Anand; Erben, Thomas; Hildebrandt, Hendrik; Muñoz, Roberto P.; Van Waerbeke, Ludovic; Côté, Patrick; Cuillandre, Jean-Charles; Duc, Pierre-Alain; Ferrarese, Laura; Gwyn, Stephen D. J.; Huertas-Company, Marc; Lançon, Ariane; Parroni, Carolina; Puzia, Thomas H.

    2016-09-01

    We build a background cluster candidate catalog from the Next Generation Virgo Cluster Survey (NGVS) using our detection algorithm RedGOLD. The NGVS covers 104 deg2 of the Virgo cluster in the {u}* ,g,r,i,z-bandpasses to a depth of g ˜ 25.7 mag (5σ). Part of the survey was not covered or has shallow observations in the r band. We build two cluster catalogs: one using all bandpasses, for the fields with deep r-band observations (˜20 deg2), and the other using four bandpasses ({u}* ,g,i,z) for the entire NGVS area. Based on our previous Canada-France-Hawaii Telescope Legacy Survey W1 studies, we estimate that both of our catalogs are ˜100% (˜70%) complete and ˜80% pure, at z ≤ 0.6 (z ≲ 1), for galaxy clusters with masses of M ≳ 1014 M ⊙. We show that when using four bandpasses, though the photometric redshift accuracy is lower, RedGOLD detects massive galaxy clusters up to z ˜ 1 with completeness and purity similar to the five-band case. This is achieved when taking into account the bias in the richness estimation, which is ˜40% lower at 0.5 ≤ z < 0.6 and ˜20% higher at 0.6 < z < 0.8, with respect to the five-band case. RedGOLD recovers all the X-ray clusters in the area with mass M 500 > 1.4 × 1014 M ⊙ and 0.08 < z < 0.5. Because of our different cluster richness limits and the NGVS depth, our catalogs reach lower masses than the published redMaPPer cluster catalog over the area, and we recover ˜90%-100% of its detections.

  9. ELF (Extremely Low Frequency) Biological Effects Literature Data Base Management System.

    DTIC Science & Technology

    1985-10-01

    x x x X X x xx X x X x X X XXX x,. x x...X x x X XX X X x X X X X Xx.- x - .x X > X x x X xX( x(~~ X <> ., x x X x X X x x x xX Xx X X xX X " X X X X x X X x X x p X XX XX XX x x xx x X ...S X X X x X X X X X X X ) X x X~ X X> X> X> X#x x X Xx X Xx X x x x ,’,’’ X- xx x X××XX x x× X X × .’.’-X •xx xx XXXXX Xx× X x x x.. - XXX XXX XxX

  10. Repro-Modeling Applied to the Simplification of TARADCOM Computer Models

    DTIC Science & Technology

    1976-12-01

    XXX Regions...in *8 76 % XXX 00000 00x zX NUN CXXx W Wx 0000000 000 XXX xX 3- Xx xx NXX 0000000 0000 xxu 0 XX.X. x 000 0000000 XXX x 00 00000 XXX XXX ...xx x WX~x 0o 0000 Xx x N:x:0. 00 000 xX )I xX go Xx xx 00 00 N .x 00 00 XXX a X x WNW 00 00 Nxx

  11. Effect "negative viscosity" as possible mechanism of ozone hole are formed above Antarctica at last quarter of XX century

    NASA Astrophysics Data System (ADS)

    Andrey, Nagurny

    2010-05-01

    One of the possible mechanisms of the ozone hole formation over Antarctica can be a meridional transport of ozone deficit by the mesoscale vortexes generated by perturbations in the stratospheric circumpolar vortex. This transport can occur against the global ozone gradient in the polar stratosphere. An assessment of the value and sign of the macro-turbulent exchange coefficient provides understanding of the intensity and direction of large-scale vortex diffusion in the framework of the equations of heat, moisture and momentum transfer. The local viscosity can be negative at this since the turbulent viscosity, heat conductivity and diffusion coefficients characterize already not the physical properties of fluids and gases but the statistical properties of their turbulent motions. According to the definition of Viktor Starr (1968), "negative viscosity" leads to the impulse transfer against a zonal gradient. So, the small-scale energy passes to zonal energy and in the equations of transfer of the conservative properties of the atmosphere (temperature, humidity, ozone, etc.), the transfer can be against the average zonal gradient. To estimate macro-turbulent exchange coefficients, we shall use a procedure, which is similar by structure to the procedure, which is used for reduction of the non-linear Burger's equation to the linear equation of heat conductivity. Whereas in 1980, one mainly observes the positive values of meridional turbulent exchange coefficient, but to 1988 and especially in 2003, these values within the stratospheric vortex are predominantly negative. The growth of the negative value of the meridional transfer coefficient simultaneously with the increased area and the "depth" of the ozone hole allow us to interpret the development of the ozone hole in terms of the mechanism of "negative" viscosity, responsible for transfer of kinetic energy by smaller-scale vortexes towards large-scale perturbations enhancing thus the intensity of the stratospheric circumpolar vortex. Correspondingly, ozone in this process is transferred against the latitudinal gradient of its distribution, creating the ozone deficit within the stratospheric vortex and its maximum at the periphery. One of the peculiarities of the ozone hole in Antarctica is presence of the maximum ozone value at the periphery of the ozone hole. There is an impression that the ozone maximum and minimum over Antarctica are formed by one mechanism within the circumpolar stratospheric vortex over the South Pole. The mechanism of the "negative viscosity" quite fits in principle this role. Calculations showed that exactly in spring (in September in the South Polar Area) values of meridional turbulent exchange coefficient achieve their maximum negative values. In the process of occurrence of the ozone hole and its development beginning from 1982, the scale of the stratospheric circumpolar vortex in the South Polar Area decreases with a simultaneous increase of the vortex intensity ("depth"). The latter seems to contribute to appearance of the ‘negative viscosity" effect, when ozone is transported from the stratospheric vortex to its external boundary, creating the ozone deficit inside the vortex and its excess at the periphery of the circumpolar vortex. A decrease of the vortex scale can be caused by a combined impact of natural multiyear fluctuations of the general circulation (for example, a 40-year period) and a continuously increasing anthropogenic impact.

  12. Male gender identity in children with 46,XX DSD with congenital adrenal hyperplasia after delayed presentation in mid-childhood.

    PubMed

    Chowdhury, Tanvir Kabir; Laila, Kamrun; Hutson, John M; Banu, Tahmina

    2015-12-01

    Girls with congenital adrenal hyperplasia (CAH) diagnosed at birth have some masculine behaviors but rarely convert to male gender. In developing countries, however, diagnosis and treatment (with secondary androgen suppression) are delayed. We aimed to assess effect of delayed treatment of CAH on gender identity. As part of a cross-sectional, case-control study of children with disorders of sex development (DSD), there were 11 patients with CAH. Patients and caregivers answered a questionnaire about gender identity, and behavior was assessed by observing toy play. Patients were examined for Prader score and gender identity. Of 11 CAH patients initially raised as girls, 3 (27%) had converted to male gender at presentation (5, 9, 9years) (Prader 3, 4, 4). Of the remaining 8 patients, one 4-year-old (Prader 2) had a male gender identity score. The remaining girls (2-13years, mean 8.1) (Prader 1-3) had gender identity scores in the female range. One third (4/11) of CAH patients presenting in mid-childhood had male gender identity scores, and ¾ had assumed male gender role. Although social and cultural factors are important in developing countries, this result suggests that delayed treatment may trigger male gender identity, and delayed female genital surgery may be unwise. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. Experience and Perspectives of Art History Development in Educational Space of Siberia at the Turn of XX-XXI ?enturies

    ERIC Educational Resources Information Center

    Nekhvyadovich, Larisa Ivanovna; Chernyaeva, Irina Valerievna

    2016-01-01

    The article has a program-analytical nature, contains an analysis and assessment of the scientific school of T. M. Stepanskaya, Doctor of Arts, professor, member of Russian Union of Artists. The goal of T. M. Stepanskaya's professional activity is incorporation of Art History in higher educational institutions in Siberia. The authors consider the…

  14. Grafting onto wool. XX. Graft copolymerization of vinyl monomers by use of redox initiators. Comparison of monomer reactivities

    SciTech Connect

    Misra, B.N.; Singha, A.S.; Sharma, R.K.

    1982-04-01

    Methyl methacrylate (MMA) and ethylacrylate (EA) have been graft copolymerized onto Himachali wool in aqueous medium by using a ferrous ammonium sulfate-hydrogen peroxide (FAS-H/sub 2/O/sub 2/) system as redox initiator. Percentage of grafting has been determined as functions of concentration of monomer, molar ratio of (FAS)/(H/sub 2/O/sub 2/), time, and temperature. Percentage of grafting is found to depend upon the molar ratio of (FAS)/(H/sub 2/O/sub 2/). An attempt has been made to compare the reactivities of the acceptor monomer (MMA and EA) with that of the donor monomer (VAc) toward grafting onto wool.

  15. Planck intermediate results. XX. Comparison of polarized thermal emission from Galactic dust with simulations of MHD turbulence

    NASA Astrophysics Data System (ADS)

    Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Alina, D.; Alves, M. I. R.; Aniano, G.; Armitage-Caplan, C.; Arnaud, M.; Arzoumanian, D.; Ashdown, M.; Atrio-Barandela, F.; Aumont, J.; Baccigalupi, C.; Banday, A. J.; Barreiro, R. B.; Battaner, E.; Benabed, K.; Benoit-Lévy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Boulanger, F.; Bracco, A.; Burigana, C.; Cardoso, J.-F.; Catalano, A.; Chamballu, A.; Chiang, H. C.; Christensen, P. R.; Colombi, S.; Colombo, L. P. L.; Combet, C.; Couchot, F.; Coulais, A.; Crill, B. P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Dickinson, C.; Diego, J. M.; Donzelli, S.; Doré, O.; Douspis, M.; Dupac, X.; Efstathiou, G.; Enßlin, T. A.; Eriksen, H. K.; Falgarone, E.; Fanciullo, L.; Ferrière, K.; Finelli, F.; Forni, O.; Frailis, M.; Fraisse, A. A.; Franceschi, E.; Galeotta, S.; Ganga, K.; Ghosh, T.; Giard, M.; Giraud-Héraud, Y.; González-Nuevo, J.; Górski, K. M.; Gregorio, A.; Gruppuso, A.; Guillet, V.; Hansen, F. K.; Harrison, D. L.; Helou, G.; Hernández-Monteagudo, C.; Hildebrandt, S. R.; Hivon, E.; Hobson, M.; Holmes, W. A.; Hornstrup, A.; Huffenberger, K. M.; Jaffe, A. H.; Jaffe, T. R.; Jones, W. C.; Juvela, M.; Keihänen, E.; Keskitalo, R.; Kisner, T. S.; Kneissl, R.; Knoche, J.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lamarre, J.-M.; Lasenby, A.; Lawrence, C. R.; Leonardi, R.; Levrier, F.; Liguori, M.; Lilje, P. B.; Linden-Vørnle, M.; López-Caniego, M.; Lubin, P. M.; Macías-Pérez, J. F.; Maino, D.; Mandolesi, N.; Maris, M.; Marshall, D. J.; Martin, P. G.; Martínez-González, E.; Masi, S.; Matarrese, S.; Mazzotta, P.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Miville-Deschênes, M.-A.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Munshi, D.; Murphy, J. A.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C. B.; Noviello, F.; Novikov, D.; Novikov, I.; Oxborrow, C. A.; Pagano, L.; Pajot, F.; Paoletti, D.; Pasian, F.; Pelkonen, V.-M.; Perdereau, O.; Perotto, L.; Perrotta, F.; Piacentini, F.; Piat, M.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Popa, L.; Pratt, G. W.; Prunet, S.; Puget, J.-L.; Rachen, J. P.; Reinecke, M.; Remazeilles, M.; Renault, C.; Ricciardi, S.; Riller, T.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Roudier, G.; Rusholme, B.; Sandri, M.; Scott, D.; Soler, J. D.; Spencer, L. D.; Stolyarov, V.; Stompor, R.; Sudiwala, R.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J. A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Tucci, M.; Umana, G.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vielva, P.; Villa, F.; Wade, L. A.; Wandelt, B. D.; Zonca, A.

    2015-04-01

    Polarized emission observed by Planck HFI at 353 GHz towards a sample of nearby fields is presented, focusing on the statistics of polarization fractions p and angles ψ. The polarization fractions and column densities in these nearby fields are representative of the range of values obtained over the whole sky. We find that: (i) the largest polarization fractions are reached in the most diffuse fields; (ii) the maximum polarization fraction pmax decreases with column density NH in the more opaque fields with NH> 1021 cm-2; and (iii) the polarization fraction along a given line of sight is correlated with the local spatial coherence of the polarization angle. These observations are compared to polarized emission maps computed in simulations of anisotropic magnetohydrodynamical turbulence in which we assume a uniform intrinsic polarization fraction of the dust grains. We find that an estimate of this parameter may be recovered from the maximum polarization fraction pmax in diffuse regions where the magnetic field is ordered on large scales and perpendicular to the line of sight. This emphasizes the impact of anisotropies of the magnetic field on the emerging polarization signal. The decrease of the maximum polarization fraction with column density in nearby molecular clouds is well reproduced in the simulations, indicating that it is essentially due to the turbulent structure of the magnetic field: an accumulation of variously polarized structures along the line of sight leads to such an anti-correlation. In the simulations, polarization fractions are also found to anti-correlate with the angle dispersion function 𝒮. However, the dispersion of the polarization angle for a given polarization fraction is found to be larger in the simulations than in the observations, suggesting a shortcoming in the physical content of these numerical models. In summary, we find that the turbulent structure of the magnetic field is able to reproduce the main statistical properties of the dust polarization as observed in a variety of nearby clouds, dense cores excluded, and that the large-scale field orientation with respect to the line of sight plays a major role in the quantitative analysis of these statistical properties. Appendices are available in electronic form at http://www.aanda.org

  16. Selected Rapporteur Summaries from the XX World Congress of Psychiatric Genetics, Hamburg, Germany, October 14-18, 2012

    PubMed Central

    Anderson-Schmidt, Heike; Beltcheva, Olga; Brandon, Mariko D; Byrne, Enda M; Diehl, Eric J; Duncan, Laramie; Gonzalez, Suzanne D; Hannon, Eilis; Kantojärvi, Katri; Karagiannidis, Iordanis; Kos, Mark Z; Kotyuk, Eszter; Laufer, Benjamin I; Mantha, Katarzyna; McGregor, Nathaniel W; Meier, Sandra; Nieratschker, Vanessa; Spiers, Helen; Squassina, Alessio; Thakur, Geeta A; Tiwari, Yash; Viswanath, Biju; Way, Michael J; Wong, Cybele CP; O'Shea, Anne; DeLisi, Lynn E

    2014-01-01

    The XXth World Congress of Psychiatric Genetics (WCPG), sponsored by The International Society of Psychiatric Genetics (ISPG) took place in Hamburg, Germany on October 14-18, 2012. Approximately 600 participants gathered to discuss the latest findings in this rapidly advancing field. The following report was written by student travel awardees. Each was assigned sessions as rapporteurs. This manuscript represents topics covered in most, but not all, oral presentations during the conference, and some of the major notable new findings reported at this 2012 WCPG. PMID:23341144

  17. Follow-Up Study of Former Computer Information Systems Students, 1986-1990. Volume XX, No. 6.

    ERIC Educational Resources Information Center

    Bender, Virginia; And Others

    In fall 1991, a follow-up study was conducted of former Computer Information System (CIS) program students at William Rainey Harper College (WRHC), in Palatine, Illinois, in an effort to evaluate and provide future direction for the program. All students who had taken four or more CIS courses between summer 1986 and spring 1990, but were not…

  18. 75 FR 60756 - Information Collection; OMB Control No. 3090-00XX; Reporting and Use of Information Concerning...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-01

    ... report on terminations of awards due to material failure to comply with award terms and conditions; administrative agreements with entities to resolve suspension or debarment proceedings; and findings that... State award. As section 872 requires, an entity also would be able to submit comments to the data...

  19. Experimental investigation of factors limiting slow axis beam quality in 9xx nm high power broad area diode lasers

    SciTech Connect

    Winterfeldt, M. Crump, P.; Wenzel, H.; Erbert, G.; Tränkle, G.

    2014-08-14

    GaAs-based broad-area diode lasers are needed with improved lateral beam parameter product (BPP{sub lat}) at high power. An experimental study of the factors limiting BPP{sub lat} is therefore presented, using extreme double-asymmetric (EDAS) vertical structures emitting at 910 nm. Continuous wave, pulsed and polarization-resolved measurements are presented and compared to thermal simulation. The importance of thermal and packaging-induced effects is determined by comparing junction -up and -down devices. Process factors are clarified by comparing diodes with and without index-guiding trenches. We show that in all cases studied, BPP{sub lat} is limited by a non-thermal BPP ground-level and a thermal BPP, which depends linearly on self-heating. Measurements as a function of pulse width confirm that self-heating rather than bias-level dominates. Diodes without trenches show low BPP ground-level, and a thermal BPP which depends strongly on mounting, due to changes in the temperature profile. The additional lateral guiding in diodes with trenches strongly increases the BPP ground-level, but optically isolates the stripe from the device edges, suppressing the influence of the thermal profile, leading to a BPP-slope that is low and independent of mounting. Trenches are also shown to initiate strain fields that cause parasitic TM-polarized emission with large BPP{sub lat}, whose influence on total BPP{sub lat} remains small, provided the overall polarization purity is >95%.

  20. Experimental investigation of factors limiting slow axis beam quality in 9xx nm high power broad area diode lasers

    NASA Astrophysics Data System (ADS)

    Winterfeldt, M.; Crump, P.; Wenzel, H.; Erbert, G.; Tränkle, G.

    2014-08-01

    GaAs-based broad-area diode lasers are needed with improved lateral beam parameter product (BPPlat) at high power. An experimental study of the factors limiting BPPlat is therefore presented, using extreme double-asymmetric (EDAS) vertical structures emitting at 910 nm. Continuous wave, pulsed and polarization-resolved measurements are presented and compared to thermal simulation. The importance of thermal and packaging-induced effects is determined by comparing junction -up and -down devices. Process factors are clarified by comparing diodes with and without index-guiding trenches. We show that in all cases studied, BPPlat is limited by a non-thermal BPP ground-level and a thermal BPP, which depends linearly on self-heating. Measurements as a function of pulse width confirm that self-heating rather than bias-level dominates. Diodes without trenches show low BPP ground-level, and a thermal BPP which depends strongly on mounting, due to changes in the temperature profile. The additional lateral guiding in diodes with trenches strongly increases the BPP ground-level, but optically isolates the stripe from the device edges, suppressing the influence of the thermal profile, leading to a BPP-slope that is low and independent of mounting. Trenches are also shown to initiate strain fields that cause parasitic TM-polarized emission with large BPPlat, whose influence on total BPPlat remains small, provided the overall polarization purity is >95%.

  1. El Material Suplementario En Los Diccionarios Bilingues Espanol-Ingles Mas Representativos De Los Siglos XX y XXI

    ERIC Educational Resources Information Center

    Fischer Dorantes, Erica

    2010-01-01

    This work is one of the first attempts to make a detailed and comparative analysis of the supplementary material of several bilingual English-Spanish dictionaries from the 20th and 21st centuries. It examines the historical development of prefaces and appendices in the most representative bilingual English-Spanish dictionaries that have…

  2. El Material Suplementario En Los Diccionarios Bilingues Espanol-Ingles Mas Representativos De Los Siglos XX y XXI

    ERIC Educational Resources Information Center

    Fischer Dorantes, Erica

    2010-01-01

    This work is one of the first attempts to make a detailed and comparative analysis of the supplementary material of several bilingual English-Spanish dictionaries from the 20th and 21st centuries. It examines the historical development of prefaces and appendices in the most representative bilingual English-Spanish dictionaries that have…

  3. [Publications derived from free communications at the XX Congress of the Anesthesiology and Resuscitation Spanish Association (Anesthesia 92)].

    PubMed

    Castillo, J; García-Guasch, R; Cifuentes, I

    2000-02-01

    To analyze the publication in MEDLINE-indexed journals of articles derived from free presentations at the Twentieth Congress of the Spanish Society of Anesthesiology (SEDAR) (Anestesia 92) held in 1992. Two of the authors independently investigated the publication of research presented at Anestesia 92 in MEDLINE-indexed journals, carrying out a search of authors' names between 1990 and 1998 with no restrictions on language or type of publication. We obtained year of publication and names of journals and extracted the abstracts, then analyzing the number and order of authors, content and time elapsing between the congress and publication. Eighty-four articles (17.1%) were published based on 491 congress presentations, with a mean time to publication of 1.8 years (range -2 to 6). Journals specializing in anesthesiology published 79.8%, and Revista Espanola de Anestesiología y Reanimación published 59.5%. Different authors were listed for published articles and congress presentations in 92.9% and the first author had changed in 35.7%. The content of a published article was similar to that of the congress presentation in 46% and scope was reduced for publication in 35.7%. Few publications were derived from free presentations at Anestesia 92 and major changes were made in authors and content between congress presentation and publication.

  4. Scanning Tunneling Microscopy of the Organic Conductors (TMTSF)2X(X = C1O4-, REO4-)

    DTIC Science & Technology

    1992-02-25

    when the 2 vertical position of the tip is fixed, variation in iT is measured that reflects the spatial dependence of p(r,EF). In either mode, the...E.; Terris, B. D.; Wang, H. H.; Carlson, K. D.; Williams, J. M. Phys. Rev. Lett.1986, 57, 629-632. (c) Maruyama, Y.; Inabe, T.; Yamochi, H.; Salto

  5. History of the Astronomy in the Century XX: Perspective Cosmo-philosophically of its Advances and their Origenes

    NASA Astrophysics Data System (ADS)

    Fernandez Quintano, Jose

    The man has for the first time been able to contemplate from the Earth space. For the first time, a cosmological theory, the big-bang, physically explains the origin of the universe. But also, for the first time, the man has seen reunited the origins of this celestial science through the paleolithics antecedents, and just discovered in Mesopotamia. Now, the philosophy proposes through the thinking J. Habermas, an ideal community of speech. Now, astronomy proposes a model that explains the causal origins of all the created one. Of the assembly of recoveries, it excels the recovery of the old cuneiform cultures. Compared vision of assembly and between the assyriologists outstanding work like Epping, Strassmaier and Kugler, goes to der Waerden and Neugebauer, along with the work of eminent physicists and thinkers of this century.

  6. Missing XX Chromosomes or Gender In/equity in Design and Technology Education? The Case of British Columbia.

    ERIC Educational Resources Information Center

    Braundy, Marcia; O'Riley, Pat; Petrina, Stephen; Dalley, Stephen; Paxton, Anabelle

    2000-01-01

    Presents data demonstrating the disproportionately low numbers of female technology teachers, teacher educators, and students in British Columbia. Discusses recruiting inequities, history of gendering in industrial technology classrooms, and resistance to gender-specific interventions. Outlines a technology education curriculum for all students.…

  7. Theoretical mechanisms for synthesis of carcinogen-induced embryonic proteins: XX. Embryonic gene perturbations expressed in terms of matrix algebra.

    PubMed

    Hancock, R L

    1988-09-01

    Simple matrix expressions can be devised for gene repressor associations that lend themselves to manipulations such as linear transformation matrices. Such transformation matrices act in perturbing representations for given repressed genic states and may be analogous to carcinogens. Although the matrix algebraic expressions are developed by using simple repressor theory, it can equally serve to represent modifications of chromatin domains that may be more consistent with mechanisms of derepression of embryonic genes. In general, it is proposed that the potentially exploitable algebras such as abstract, geometric, matrix, vector and tensor be a subset of mathematical biology termed "Bioalgebraic Field Theory".

  8. Dynamics of glass-forming liquids. XX. Third harmonic experiments of non-linear dielectric effects versus a phenomenological model

    NASA Astrophysics Data System (ADS)

    Kim, Pyeongeun; Young-Gonzales, Amanda R.; Richert, Ranko

    2016-08-01

    We have re-measured the third harmonic non-linear dielectric response of supercooled glycerol using zero-bias sinusoidal electric fields, with the aim of comparing the resulting susceptibilities with a phenomenological model of non-linear dielectric responses. In the absence of known chemical effects in this liquid, the present model accounts for three sources of non-linear behavior: dielectric saturation, field induced entropy reduction, and energy absorption from the time dependent field. Using parameters obtained from static high field results, the present model reproduces the characteristic features observed in the third harmonic susceptibility spectra: a low frequency plateau originating from dielectric saturation and a peak positioned below the loss peak frequency whose amplitude increases with decreasing temperature. Semi-quantitative agreement is achieved between experiment and the present model, which does not involve spatial scales or dynamical correlations explicitly. By calculating the three contributions separately, the model reveals that the entropy effect is the main source of the "hump" feature of this third harmonic response.

  9. [Mental signs of individual predisposition to madness in French psychiatry of the late XIX-early XX centuries].

    PubMed

    Pyatnitskiy, N Yu

    2016-01-01

    The author analyze conceptions of mental signs of predisposition (diathesis, vulnerability) to non-psychotic and delusional mental disorders of functional origin described in the works of leading French psychiatrists of the late 19th/early 20th centuries (E. Regis, P. Serieux, J. Capgras, E. Dupre, J. Levy-Valensi etc). The descriptions of characteristics of some constitutional types and the differences in the structure of constitutional types and the structure of delusional disorders developed on their basis are compared.

  10. Women with spontaneous 46,XX primary ovarian insufficiency (hypergonadotropic hypogonadism) have lower perceived social support than control women

    PubMed Central

    Orshan, Susan A.; Ventura, June L.; Covington, Sharon N.; Vanderhoof, Vien H.; Troendle, James F.; Nelson, Lawrence M.

    2009-01-01

    Objective To test the hypothesis that women with spontaneous primary ovarian insufficiency differ from control women with regard to perceived social support and to investigate the relationship between perceived social support and self-esteem. Design Cross-sectional Setting Mark O. Hatfield Clinical Research Center, National Institutes of Health. Patient(s) Women diagnosed with spontaneous primary ovarian insufficiency (N=154) at a mean age of 27 years and healthy control women (N=63). Intervention(s) Administration of validated self-reporting instruments. Main Outcome Measure(s) Personal Resource Questionnaire-85 (PRQ85), Rosenberg Self-Esteem Scale Result(s) Women with primary ovarian insufficiency had significantly lower scores than controls on the perceived social support scale and the self-esteem scale. The findings remained significant after modeling with multivariate regression for differences in age, marital status, and having children. In patients there was a significant positive correlation between self-esteem scores and perceived social support. We found no significant differences in perceived social support or self-esteem related to marital status, whether or not they had children, or time since diagnosis. Conclusion(s) This evidence supports the need for prospective controlled studies. Strategies to improve social support and self-esteem might provide a therapeutic approach to reduce the emotional suffering that accompanies the life-altering diagnosis of spontaneous primary ovarian insufficiency. PMID:18829005

  11. Statistical data on forest fund of Russia and changing of forest productivity in the second half of XX century

    Treesearch

    Alexeyev V.A.; Markov M.V.; R.A. Birdsey; Birdsey R.A.

    2004-01-01

    Contains statistical data on area and growing-stock volume of forest lands in Oblasts, Krays and Republics of Russian Federation, for the period 1961-1998. Positive dynamics of average growing stock for coniferous, deciduous hardwood and deciduous softwood tree stands by stand-age groups were disclosed. The impact of main anthropogenic and natural factors, including...

  12. High-brightness, high-power 9xx-nm diode laser bars: developments at JENOPTIK diode lab

    NASA Astrophysics Data System (ADS)

    Sebastian, J.; Schulze, H.; Hülsewede, R.; Hennig, P.; Meusel, J.; Schröder, M.; Schröder, D.; Lorenzen, D.

    2007-02-01

    We report present advantages of high power 9xxnm diode laser bars for pumping of disc laser and especially for pumping fibre lasers and amplifiers. The strong demand for reduce system costs needs to have a good compromise in improved diode laser power, conversion efficiency, reliability and beam quality leading to simplified system designs. Basis of the new generation for the 9xxnm laser diode bars at JENOPTIK Diode Lab is a low loss wave guide AlGaAs - structure with low vertical far field angle of 27° (FWHM). Recently we demonstrate an output power in excess of 500W in CW operation from a diode laser bar with 50% filling factor and 3.0mm cavity length. This record was possible due to high power conversion efficiency of >68 %, optimised facet coating technology and an excellent active cooling. New results on conductive cooled high brightness laser bars of 20% filling factor with special emphasis to the needs of high efficiency fibre coupling will be presented. Lifetime tests under long pulse conditions have demonstrated a very high reliability for 120 W laser bars with 50 % filling factor and for 60 W laser bars with 20 % and 30 % filling factor.

  13. General trends in the change in solar activity indices in the period from the late XX to early XXI century

    NASA Astrophysics Data System (ADS)

    Bruevich, E. A.; Yakunina, G. V.

    2015-12-01

    We present an analysis of observations of the indices of the sunspot numbers (SSN from the National Oceanic and Atmospheric Administration (NOAA)), the radio-emission flux at a wavelength of 10.7 cm ( F 10.7), and the Total Solar Irradiance (TSI) in cycles 22-24. We have found that the ratio of the observed values SSNobs to the calculated ones SSNsyn (from the regression relations between SSN and F 10.7) decreases after 1990 by 20-25%, rather than by 35%, as was supposed earlier. The characteristics of the most widely used SSN index, such as the decrease in sunspot numbers and magnetic field strength in small and medium spots, do not change in complete correspondence to the expected scenario of the solar activity development predicted from the flux F 10.7 in cycles 23 and 24; they also cannot be fully explained by an additional minimum of the secular cycle. We also showed that the observed SSN changes lead to an increase of the Total Solar Irradiance in activity cycles 23-24 as compared to that in cycle 22.

  14. Thermochemistry of organic, elementorganic and inorganic species. Part XX. Enthalpies of formation for free radicals of main group elements’ halogenides

    NASA Astrophysics Data System (ADS)

    Ponomarev, Dmitry; Takhistov, Viatcheslav; Slayden, Suzanne; Liebman, Joel

    2008-03-01

    General trends in thermochemistry for free radicals as the fragments of halogenated molecules of main group elements were found for the first time applying the series of isodesmic (working) reactions following the Benson's comparison of relative stabilities of free radicals in equations R+RH→ RH+R+Q, where Q is stabilization (destabilization) energy. The enthalpies of formation for parent molecules of main group elements' halogenides necessary for application of this and similar equations were presented earlier [A.V. Golovin, V.V. Takhistov, J. Mol. Struct., 784 (2006) 47.]. For fluorinated free radicals rad EF (E = Be-Ra), rad EF 2 ( rad EHF) (E = B-Tl, N-Bi) and rad EF 3 ( rad EH 2F, rad EHF 2) (E = C-Pb) the gradual decrease in stabilization by fluorine atoms was found when coming down the periodic table. This turned to destabilization for Tl, Sb, and Bi, and IVth group of elements (excluding carbon) with increasing destabilization in the row Si < Ge < Sn < Pb. The destabilization of free radicals by other halogens for IVth group of elements decreased in the row F > Cl > Br > I which was interpreted by involvement of polarizability (PAZ) effect of halogens increasing in this direction. For finding the enthalpies of formation for silicon and germanium-centered free radicals the data on ν ≡ E-H frequencies in IR-spectra were applied. Quite definite tendencies in structure/enthalpy of formation interrelationship were found for chlorinated, brominated and iodinated free radicals of IInd and IIIrd group of elements. In the VIth group the situation with F → Cl → Br → I replacement in stabilization of free radical center appeared completely different compared with II-IV groups. Owing to the high electronegativity of HO-group and low thermodynamic stability of HO rad radical all halogens highly stabilize rad OX radical and perform it in the row F < Cl-Br < I which is explained by increase of PAZ effect in this direction. All halogens are suggested to stabilize other rad EX free radicals (E = S-Po) but essentially less compared with rad OX free radicals. The tendencies in stabilization/destabilization for Vth group free radicals appeared to be intermediate between those for IVth and VIth groups.

  15. Effect of Background/Foreground Color Coding on Detection in Acoustic Data Displays

    DTIC Science & Technology

    1985-03-25

    XXX B X XX XXXX XX X X X XXX.X XXX 8 X XXX XXX X X X X XXX.X XXX B X XXX XXX X X X...X XXX.X XXX B X XXX XXXX XX X XX X XXX.X XXX 8 X XXX x XX X XX X XXX.X XXX B X XXX x XX X X X XXX .X XXX B X XXX x XX X X X...XXX.X XXX 8 X XXX XXX X X XX X XXX .X XXX B X XXX XXX X X XX X XXX.X XXX

  16. A System Dynamics Model for Assessing the Cost-Effectiveness of USAF Engineering Officer Compensation Policies.

    DTIC Science & Technology

    1980-12-01

    215 ix List of Tables Table Page I. Military Manning Projections for Officers in Career Fields 26XX, 27XX, 305X , and 55XX...CAREER FIELDS 26XX, 27XX, 305X , and 55XX* (Government Executive, 1980b; Original Source: AFMPC) FY80 FY81 FY82 FY83 FY84 Requirement 7676 7676 7676 7676...Manager 28XX - Development Engineer 305X - Communications Electronics Engineer 55XX - Civil Engineer TABLE II OFFICER RETENTION: EFGINEER RATES

  17. 39 CFR 3060.21 - Income report.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 20xx FY 20xx-1 Percent change fromSPLY Percent change fromSPLY Revenue: $x,xxx $x,xxx xxx xx.x (1) Mail and Services Revenues xxx xxx xx xx.x (2) Investment Income x,xx x,xxx xxx xx.x (3) Total Competitive Products Revenue Expenses: (4) Volume-Variable Costs x,xxx x,xxx xxx xx.x (5) Product Specific Costs x,xxx...

  18. 39 CFR 3060.21 - Income report.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 20xx FY 20xx-1 Percent change fromSPLY Percent change fromSPLY Revenue: $x,xxx $x,xxx xxx xx.x (1) Mail and Services Revenues xxx xxx xx xx.x (2) Investment Income x,xx x,xxx xxx xx.x (3) Total Competitive Products Revenue Expenses: (4) Volume-Variable Costs x,xxx x,xxx xxx xx.x (5) Product Specific Costs x,xxx...

  19. 39 CFR 3060.21 - Income report.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 20xx FY 20xx-1 Percent change fromSPLY Percent change fromSPLY Revenue: $x,xxx $x,xxx xxx xx.x (1) Mail and Services Revenues xxx xxx xx xx.x (2) Investment Income x,xx x,xxx xxx xx.x (3) Total Competitive Products Revenue Expenses: (4) Volume-Variable Costs x,xxx x,xxx xxx xx.x (5) Product Specific Costs x,xxx...

  20. 39 CFR 3060.21 - Income report.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 20xx FY 20xx-1 Percent change fromSPLY Percent change fromSPLY Revenue: $x,xxx $x,xxx xxx xx.x (1) Mail and Services Revenues xxx xxx xx xx.x (2) Investment Income x,xx x,xxx xxx xx.x (3) Total Competitive Products Revenue Expenses: (4) Volume-Variable Costs x,xxx x,xxx xxx xx.x (5) Product Specific Costs x,xxx...

  1. 39 CFR 3060.21 - Income report.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 20xx FY 20xx-1 Percent change fromSPLY Percent change fromSPLY Revenue: $x,xxx $x,xxx xxx xx.x (1) Mail and Services Revenues xxx xxx xx xx.x (2) Investment Income x,xx x,xxx xxx xx.x (3) Total Competitive Products Revenue Expenses: (4) Volume-Variable Costs x,xxx x,xxx xxx xx.x (5) Product Specific Costs x,xxx...

  2. 77 FR 69827 - Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) or Superfund...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-21

    ...) Establish or enhance the four elements:.... $XX,XXX $XX,XXX 1. Timely survey and inventory of 1. Examples.... Establish and maintain the public record... XX,XXX XX,XXX Maintain public record. Create Web site for public... XX,XXX XX,XXX Provide oversight of site assessments and cleanups. Attend training and conferences...

  3. Acoustic and Perceptual-Cognitive Factors in the Identification of 41 Environmental Sounds

    DTIC Science & Technology

    1989-10-20

    xx xx x x N IXXXX XXXXX XXXXXXX XXXXXXXXX...XXXXXXXXXXXXXXXXXXX XXX XXXXX XXXXX XXXXXXX XXXXXx S 0.5 +XX XXX XXX XXX XXXXXXXX XXXXX XXXXXXXXXXXX XXX XXXXX XXXXX XXX XXXX R ~ ~ ~ X XX .X XXXX .x x x...X XXXXx XXX x XXX ... .. .. . . XXXXX . . XXX R I . . . . XXX XX .X XXX .x XX XXX x X X x XXX X.. .... ... XXX . . . XXX Figure 1. Complete

  4. Fiber Coupled Microsphere Lasers

    DTIC Science & Technology

    2000-04-18

    XXX X X X X X X...X X X X X X X X X X X XXX XX X X X X X X X XX X XX X X X X X X X X X X X XX X X X X X X X X X X X X X X XX X X X X X X X X XX X X X X X X X X X X X X...X X XX X X X X XXX XXX X X X X X X X X X X X X XX X X XXX X X X X XXX X X X XXXXX XX XXX X X X X X XX X XX X X

  5. 49 CFR 1242.05 - Operating expense account number notation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., tools, supplies, fuels and lubricants (account 21-XX-XX); purchased services (accounts 31-XX-XX to 41-XX...: 11—Salaries and wages; 21—Materials, tools, supplies, fuels, and lubricants; 30 or 41—Purchased...

  6. 49 CFR 1242.05 - Operating expense account number notation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., tools, supplies, fuels and lubricants (account 21-XX-XX); purchased services (accounts 31-XX-XX to 41-XX...: 11—Salaries and wages; 21—Materials, tools, supplies, fuels, and lubricants; 30 or 41—Purchased...

  7. 49 CFR 1242.05 - Operating expense account number notation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., tools, supplies, fuels and lubricants (account 21-XX-XX); purchased services (accounts 31-XX-XX to 41-XX...: 11—Salaries and wages; 21—Materials, tools, supplies, fuels, and lubricants; 30 or 41—Purchased...

  8. Chamber Tests with Human Subjects XX. Hypersensitivity to H as Demonstrated by Patch Tests Before and After Chamber Exposure to H Vapor

    DTIC Science & Technology

    1946-05-15

    intense erythema 4 a. erythema with edema b. dry scaling of scrotum c. maceration of axillary skin 5 a. vesicle b. numerous pinpoint vesicles c. crusting... skin reaction following exposure to H vapor in the man-chamber are discussed. Eight kodachrone prints, illustrating pertinent features, are included...Reactions for a Given Test Dose - 12 F. Changes in Threshold ------------------ 12 G. Abnormal Skin Reactions Following Chamber Exposures to H Vapor

  9. Female Teachers Training in Educational Grades of Women's Gymnasia in Kazan in the Last Third of the XIX--Early XX Centuries

    ERIC Educational Resources Information Center

    Kornilova, Irina V.; Magsumov, Timur A.; Shakirov, Rasul R.

    2016-01-01

    The purpose of the article is to study the way the female teacher education was formed in late imperial Russia. The subject of the study is the specific element of this process in Kazan province, being a multi-ethnic region. The article analyses a number of issues, the ones related to the activities of the two Kazan gymnasia--Maryinskaya and…

  10. Apuntes en torno a la caoba dominicana y hondureña en Puerto Rico durante el siglo XIX e inicios del siglo XX

    Treesearch

    Carlos M. Domínguez Cristóbal

    2009-01-01

    La introducción de la caoba dominicana a Puerto Rico es uno de los temas que no solo interesan a los geobotànicos. Dentro de esa perspectiva el Instituto Internacional de Dasonomía Tropical (IIDT) posee un legado de significativa contribución para con el tema. No obstante, este tema no ha sido considerado desde la perspectiva de los...

  11. Characterization of a 5.8-Mb interstitial deletion of chromosome 3p in a girl with 46,XX,inv(7)dn karyotype and phenotypic abnormalities.

    PubMed

    Morales, C; Mademont-Soler, I; Armengol, L; Milà, M; Badenas, C; Andrés, S; Soler, A; Sánchez, A

    2009-01-01

    Interstitial deletions of the short arm of chromosome 3 are rare, and a specific clinical phenotype has not been defined. We report the first isolated cryptic proximal interstitial 3p deletion, del(3)(p12.3p13), assessed by array-based comparative genomic hybridization in a girl with an inversion of chromosome 7, whose phenotype includes neurodevelopmental delay, growth retardation, dysmorphic facial features, hypophysis hypoplasia, gastroesophageal reflux, clinodactyly, preauricular appendix, and myopia. Her features are similar to those observed in the previously reported cases of proximal 3p deletions overlapping with our imbalance, indicating that her clinical manifestations are likely to be due to the deletion. As our patient's imbalance is the first non-cytogenetically visible proximal interstitial 3p deletion uncomplicated by other imbalances, its characterization has allowed us to narrow the minimal deletion interval associated with growth retardation and neurodevelopmental delay to the 3p12.3-p13 region. Among the genes found in this region, ROBO1, ROBO2, PDZRN3 and CNTN3 might play a role in the neurodevelopmental delay of the patient. This study provides additional evidence that cryptic imbalances anywhere along the genome can be found in patients with phenotypic abnormalities and a balanced chromosome rearrangement. (c) 2009 S. Karger AG, Basel.

  12. Photochemical Tissue Bonding for Military Medical Applications Practical Low Cost Low Damage Blood Vessel Repair: Albumin Stent Bonded With 19xx nm Laser

    DTIC Science & Technology

    2011-02-24

    control number. 1. REPORT DATE 24 FEB 2011 2. REPORT TYPE 3. DATES COVERED 00-11-2008 to 00-02-2011 4. TITLE AND SUBTITLE Photochemical Tissue...Lasers in Surgery and Medicine. Objectives Task 1.1, Extrusion machine design One critical element of the design of the albumin stent extruder was...when heated and solidify upon cooling. The new design included two thermocouples (Omega Engineering , Stamford, CT), four heating rods (Omega

  13. Unique unbalanced X;X translocation (Xq22;p11.2) in a woman with primary amenorrhea but without Ullrich-Turner syndrome

    SciTech Connect

    Letterie, G.S.

    1995-12-04

    This is a report of a patient with delayed puberty and a previously unreported translocation 46,X,-X,+der(X),t(X;X) (q22;p11.2) without any manifestations of Ullrich-Turner syndrome. The relationship of this unbalanced translocation to the critical region hypothesis is discussed. 6 refs., 3 figs.

  14. Deletion 2q: two new cases with karyotypes 46,XY,del(2)(q31q33) and 46,XX,del(2)(q36).

    PubMed Central

    Young, R S; Shapiro, S D; Hansen, K L; Hine, L K; Rainosek, D E; Guerra, F A

    1983-01-01

    We describe the clinical and cytogenetic findings of two patients with deletions of the long arm of chromosome 2. One has an interstitial deletion identical to that found in a previously reported patient, although they are phenotypically dissimilar. The other patient has a terminal deletion, the first such deletion reported to date. Images PMID:6876110

  15. [Mineral springs on the north-east of Caucasus and its role in the treatment of soldiers of the Russian army in XIX--beginning XX c].

    PubMed

    Akhmadov, T Z; Poddubnyĭ, M V

    2013-07-01

    The article is concerned to the history of formation of sanitary-treatment stations on the North Caucasus, in Chechnya (Goryachevodsky and Mikhailovsky mineral springs) till 1917 year. The basis of the article are archive documents, scientific papers of contemporaries and official documents. Goryachevodsky and Mikhailovsky mineral springs were more than 70 years the one the best recreative base of the Caucasian standing army including the caucasian cossack troop. The sanitary-treatment stations were of great importance during the active military actions with Hill people within the territory of Chechnya and Dagestan, during the Crimean War (1853-1856), The Russo-Turkish War of 1877-1878 and the First World War (1914-1918), when the amount of the wounded and ill soldiers increased.

  16. ASME N511-19XX, Standard for periodic in-service testing of nuclear air treatment, heating, ventilating and air conditioning systems

    SciTech Connect

    1997-08-01

    A draft version of the Standard is presented in this document. The Standard covers the requirements for periodic in-service testing of nuclear safety-related air treatment, heating, ventilating, and air conditioning systems in nuclear facilities. The Standard provides a basis for the development of test programs and does not include acceptance criteria, except in cases where the results of one test influence the performance of other tests. The Standard covers general inspection and test requirements, reference values, inspection and test requirements, generic tests, acceptance criteria, in-service test requirements, testing following an abnormal incident, corrective action requirements, and quality assurance. Mandatory appendices provide a visual inspection checklist and four test procedures. Non-mandatory appendices provide additional information and guidance on mounting frame pressure leak test procedure, corrective action, challenge gas substitute selection criteria, and test program development. 8 refs., 10 tabs.

  17. The XX Sex Chromosome Complement is Required in Male and Female Mice for Enhancement of Immunity Induced by Exposure to 3,4-Dichloropropionanilide.

    PubMed

    Holásková, Ida; Franko, Jennifer; Goodman, Robert L; Arnold, Arthur P; Schafer, Rosana

    2015-08-01

    The chemical propanil enhances antibody responses to a heat-killed Streptococcus pneumoniae (HKSP) vaccine. The enhanced response is dependent on gonads in females, but independent of gonads in males. The sex differences in the immune response may be due to sexual differentiation of the immune system or sex chromosome complement. To test the hypothesis that the immune system is sexually differentiated, newborn C57BL/6 pups were treated with testosterone propionate (TP) or placebo. The role of sex chromosome complement was investigated using the 4-core genotypes (FCG) model of XXF and XYF gonadal females (ovaries), and XXM and XYM gonadal males (testes). For some experiments, mice were gonadectomized or sham gonadectomized. All mice were vaccinated with HKSP, treated with propanil, and the antibody response determined at day seven. Neonatal TP did not alter the response to HKSP. In FCG mice, propanil significantly enhanced the immune response in XXF females and XXM males, but not in XYF females or XYM males. The immune system of females was not masculinized by neonatal TP treatment. Sex chromosome complement significantly contributes to the sexually dimorphic immune response after propanil exposure. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  18. Nucleophilic reactions at a vinylic center. XX. Base-catalyzed rearrangement of aryl /beta/,/beta/-dibromovinyl sulfones to Z-aryl /alpha/,/beta/-dibromovinyl sulfones

    SciTech Connect

    Shainyan, B.A.; Mirskova, A.N.

    1988-07-10

    A series of aryl /beta/,/beta/-dibromovinyl sulfones XC/sub 6/H/sub 4/SO/sub 2/CH=CBr/sub 2/ were synthesized, and their rearrangement to Z-aryl /alpha/,/beta/-dibromovinyl sulfones XC/sub 6/H/sub 4/SO/sub 2/CBr=CHBr by the action of KF /times/ 18-crown-6 in benzene was studied. The rearrangement rate increases with increase in the concentration of the base (F/sup /minus//) and with increase in the electron-withdrawing character of the substituent X (p-OMe < p-Me < H < p-Cl < m-NO/sub 2/) and does not depend on the temperature.

  19. Welding procedure specification. Supplement 1. Records of procedure qualification tests. Gas tungsten arc and shielded metal arc welding of AISI 41XX steels. [4130 and 4142 steels

    SciTech Connect

    Wodtke, C.H.; Frizzell, D.R.

    1986-06-01

    Procedure WPS-127 is qualified under Section IX of the ASME Boiler and Pressure Vessel Code for gas tungsten arc and shielded metal arc welding of AISI 4130 and 4142 steels (ASTM A519) (P-No: None), 0.438-inch wall pipe; filler metal is AMS 6457, Class 4130 MC (F-, A-No: None) (GTAW) and E8018-B2L (F-4, A-3) (GMAW): shielding gas is argon (GTAW).

  20. Advances in 7xx-nm fiber-coupled modules with application to Tm fiber laser pumping and DPAL (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Patterson, Steven G.; Guiney, Tina; Stapleton, Dean; Braker, Joseph; Alegria, Kim; Irwin, David A.; Ebert, Christopher

    2017-02-01

    DILAS has leveraged its industry-leading work in manufacturing low SWaP fiber-coupled modules extending the wavelength range to 793nm for Tm fiber laser pumping. Ideal for medical, industrial and military applications, modules spanning from single emitter-based 9W to TBar-based 200W of 793nm pump power will be discussed. The highlight is a lightweight module capable of <200W of 793nm pump power out of a package weighing < 400 grams. In addition, other modules spanning from single emitter-based 9W to TBar-based 200W of 793nm pump power will be presented. In addition, advances in DPAL modules, emitting at the technologically important wavelengths near 766nm and 780nm, will be detailed. Highlights include a fully microprocessor controlled fiber-coupled module that produces greater than 400W from a 600 micron core fiber and a line width of only 56.3pm. The micro-processor permits the automated center wavelength and line width tuning of the output over a range of output powers while retaining excellent line center and line width stability over time.

  1. Users' guides to the medical literature: XX. Integrating research evidence with the care of the individual patient. Evidence-Based Medicine Working Group.

    PubMed

    McAlister, F A; Straus, S E; Guyatt, G H; Haynes, R B

    2000-06-07

    Clinicians can use research results to determine optimal care for an individual patient by using a patient's baseline risk estimate, clinical prediction guidelines that quantitate an individual patient's potential for benefit, and published articles. We propose that when clinicians are determining the likelihood that treatment will prevent the target event (at the expense of adverse events) in a patient that they also incorporate the patient's values. The 3 main elements to joint clinical decision making are disclosure of information about the risks and benefits of therapeutic alternatives, exploration of the patient's values about both the therapy and potential outcomes, and the actual decision. In addressing the patient's risk of adverse events without treatment and risk of harm with therapy, clinicians must recognize that patients are rarely identical to the average study patient. Differences between study participants and patients in real-world practice tend to be quantitative (differences in degree of risk of the outcome or responsiveness to therapy) rather than qualitative (no risk or adverse response to therapy). The number needed to treat and number needed to harm can be used to generate patient-specific estimates relative to the risk of the outcome event. Clinicians must consider a patient's risk of adverse events from any intervention and incorporate the patient's values in clinical decision making by using information about the risks and benefits of therapeutic alternatives. JAMA. 2000;283:2829-2836

  2. Water Quality Instructional Resources Information System (IRIS): A Compilation of Abstracts to Water Quality and Water Resources Materials, Supplement XX (1984).

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus, OH. Information Reference Center for Science, Mathematics, and Environmental Education.

    Compiled are abstracts and indexes to selected print and non-print materials related to wastewater treatment and water quality education and instruction, as well as materials related to pesticides, hazardous wastes, and public participation. Sources of abstracted/indexed materials include all levels of government, private concerns, and educational…

  3. The VLT-FLAMES Tarantula survey. XX. The nature of the X-ray bright emission-line star VFTS 399

    NASA Astrophysics Data System (ADS)

    Clark, J. S.; Bartlett, E. S.; Broos, P. S.; Townsley, L. K.; Taylor, W. D.; Walborn, N. R.; Bird, A. J.; Sana, H.; de Mink, S. E.; Dufton, P. L.; Evans, C. J.; Langer, N.; Maíz Apellániz, J.; Schneider, F. R. N.; Soszyński, I.

    2015-07-01

    Context. The stellar population of the 30 Doradus star-forming region in the Large Magellanic Cloud contains a subset of apparently single, rapidly rotating O-type stars. The physical processes leading to the formation of this cohort are currently uncertain. Aims: One member of this group, the late O-type star VFTS 399, is found to be unexpectedly X-ray bright for its bolometric luminosity - in this study we aim to determine its physical nature and the cause of this behaviour. Methods: To accomplish this we performed a time-resolved analysis of optical, infrared and X-ray observations. Results: We found VFTS 399 to be an aperiodic photometric variable with an apparent near-IR excess. Its optical spectrum demonstrates complex emission profiles in the lower Balmer series and select He i lines - taken together these suggest an OeBe classification. The highly variable X-ray luminosity is too great to be produced by a single star, while the hard, non-thermal nature suggests the presence of an accreting relativistic companion. Finally, the detection of periodic modulation of the X-ray lightcurve is most naturally explained under the assumption that the accretor is a neutron star. Conclusions: VFTS 399 appears to be the first high-mass X-ray binary identified within 30 Dor, sharing many observational characteristics with classical Be X-ray binaries. Comparison of the current properties of VFTS 399 to binary-evolution models suggests a progenitor mass ≳25 M⊙ for the putative neutron star, which may host a magnetic field comparable in strength to those of magnetars. VFTS 399 is now the second member of the cohort of rapidly rotating "single" O-type stars in 30 Dor to show evidence of binary interaction resulting in spin-up, suggesting that this may be a viable evolutionary pathway for the formation of a subset of this stellar population. Based on observations collected at the European Southern Observatory under program ID 182.D-0222.

  4. Heat Capacity And Structural Relaxation In Se{sub 80-x}Te{sub 20}Ag{sub x}(x = 3 and 9) Glassy Alloys

    SciTech Connect

    Naqvi, S. Faheem; Saxena, N. S.

    2011-10-20

    This paper reports the effects of annealing time and temperature on the thermodynamics of enthalpy relaxation of Se{sub 80-x}Te{sub 20}Ag{sub x} (x = 3,9) glasses. Differential Scanning Calorimetry (DSC) method is optimized for the measurement of enthalpy relaxation in the vicinity of glass transition. The recovery of excess enthalpy ({Delta}H{sub excess}) has been calculated from the knowledge of excess specific heat ({Delta}C{sub p}). It is found that excess enthalpy released ({Delta}H{sub excess}) increase with increase in annealing time (t{sub a}). From the knowledge of excess specific heat ({Delta}C{sub p}) and {Delta}H{sub excess}, it has been found that sub-T{sub g} annealing of glass leads to decrease in enthalpy of the system and thereby taking it to the more equilibrium state.

  5. CHROMATOGRAPHIC TECHNIQUES IN PHARMACEUTICAL ANALYSIS IN POIAND: HISTORY AND THE PRESENCE ON THE BASIS OF PAPERS PUBLISHED IN SELECTED POLISH PHARMACEUTICAL JOURNALS IN XX CENTURY.

    PubMed

    Bilek, Maciej; Namieśnik, Jacek

    2016-01-01

    For a long time, chromatographic techniques and techniques related to them have stimulated the development of new procedures in the field of pharmaceutical analysis. The newly developed methods, characterized by improved metrological parameters, allow for more accurate testing of, among others, the composition of raw materials, intermediates and final products. The chromatographic techniques also enable studies on waste generated in research laboratories and factories producing pharmaceuticals and parapharmaceuticals. Based on the review of reports published in Polish pharmaceutical journals, we assessed the impact of chromatographic techniques on the development of pharmaceutical analysis. The first chromatographic technique used in pharmaceutical analysis was a so-called capillary analysis. It was applied in the 1930s to control the identity of pharmaceutical formulations. In the 1940s and 1950s, the chromatographic techniques were mostly a subject of review publications, while their use in experimental work was rare. Paper chromatography and thin layer chromatography were introduced in the 1960s and 1970s, respectively. These new analytical tools have contributed to the intensive development of research in the field of phytochemistry and the analysis of herbal medicines. The development of colunm chromatography-based techniques, i.e., gas chromatography and high performance liquid chromatography took place in the end of 20th century. Both aforementioned techniques were widely applied in pharmaceutical analysis, for example, to assess the stability of drugs, test for impurities and degradation products as well as in pharmacokinetics studies. The first decade of 21" century was the time of new detection methods in gas and liquid chromatography. The information sources used to write this article were Polish pharmaceutical journals, both professional and scientific, originating from the interwar and post-war period, i.e., "Kronika Farmaceutyczna", "Farmacja Współczesna", "Wiadomości Farmaceutyczne", "Acta Poloniae Pharmaceutica", "Farmacja Polska", "Dissertationes Pharmaceuticae", "Annales UMCS sectio DDD Phamacia". The number of published works using various chromatography techniques was assessed based on the content description of individual issues of the journal "Acta Poloniae Pharmaceutica".

  6. Effect of La surface treatments on corrosion resistance of A3 xx. x/SiC p composites in salt fog

    NASA Astrophysics Data System (ADS)

    Pardo, A.; Merino, M. C.; Arrabal, R.; Merino, S.; Viejo, F.; Coy, A. E.

    2006-02-01

    The influence of the SiC p proportion and the matrix concentration of four aluminium metal matrix composites (A360/SiC/10p, A360/SiC/20p, A380/SiC/10p, A380/SiC/20p) modified by lanthanum-based conversion or electrolysis coating was evaluated in neutral salt fog according to ASTM B 117. Lanthanum-based conversion coatings were obtained by immersion in 50 °C solution of La(III) salt and lanthanum electrolysis treatments were performed in ethylene glycol mono-butyl ether solution. These treatments preferentially covered cathodic areas such as intermetallic compounds, Si eutectic and SiC p. The kinetic of the corrosion process was studied on the basis of gravimetric tests. Both coating microstructure and nature of corrosion products were analyzed by scanning electron microscopy (SEM), atomic force microscopy (AFM), energy dispersive X-ray analysis (EDS) and low angle X-ray diffraction (XRD) before and after accelerated testing to determine the influence of microstructural changes on corrosion behaviour during exposure to the corrosive environment. The corrosion process was more influenced by the concentration of alloy elements in the matrix than by the proportion of SiC p reinforcement. Both conversion and electrolysis surface treatments improved the behaviour to salt fog corrosion in comparison with original composites without treatment. Additionally, electrolysis provided a higher degree of protection than the conversion treatment because the coating was more extensive.

  7. [THE SCIENTIFIC REVOLUTION IN MEDICINE OF THE LAST QUARTER OF XIX-FIRST HALF OF XX CENTURIES. REPORT II. THE OUTSET OF REVISION OF MEDICAL SCIENCE].

    PubMed

    Stochik, A M; Zatravkin, S N

    2015-01-01

    The article affirms that onset of revision of picture of analyzed reality, methodological approaches to studying of vital activity of human organism and philosophical basics of medical science refers to 1878 and is related to publishing of "The course of general physiology" by French physiologist Claude Bernard. The implemented analysis of the text of this work permit to establish that C. Bernard undertook an attempt to introduce conception of human organism as a processing system being self-reproduced as. a result of interaction with environment due to mechanisms of self-regulation. The necessity was substantiated to make experiment the leading method of cognition of vital activity. The living wholeness (organism, cell) was proposed to be an object of experimentation. In this living wholeness its natural capacities to self-regulation of main vital processes can be preserved at its maximum. The new senses were introduced into ontological categories of thing, process, causality, portion and whole.

  8. Mechanisms of mitochondrial holocytochrome c synthase and the key roles played by cysteines and histidine of the heme attachment site, Cys-XX-Cys-His.

    PubMed

    Babbitt, Shalon E; San Francisco, Brian; Mendez, Deanna L; Lukat-Rodgers, Gudrun S; Rodgers, Kenton R; Bretsnyder, Eric C; Kranz, Robert G

    2014-10-17

    Mitochondrial cytochrome c assembly requires the covalent attachment of heme by thioether bonds between heme vinyl groups and a conserved CXXCH motif of cytochrome c/c1. The enzyme holocytochrome c synthase (HCCS) binds heme and apocytochrome c substrate to catalyze this attachment, subsequently releasing holocytochrome c for proper folding to its native structure. We address mechanisms of assembly using a functional Escherichia coli recombinant system expressing human HCCS. Human cytochrome c variants with individual cysteine, histidine, double cysteine, and triple cysteine/histidine substitutions (of CXXCH) were co-purified with HCCS. Single and double mutants form a complex with HCCS but not the triple mutant. Resonance Raman and UV-visible spectroscopy support the proposal that heme puckering induced by both thioether bonds facilitate release of holocytochrome c from the complex. His-19 (of CXXCH) supplies the second axial ligand to heme in the complex, the first axial ligand was previously shown to be from HCCS residue His-154. Substitutions of His-19 in cytochrome c to seven other residues (Gly, Ala, Met, Arg, Lys, Cys, and Tyr) were used with various approaches to establish other roles played by His-19. Three roles for His-19 in HCCS-mediated assembly are suggested: (i) to provide the second axial ligand to the heme iron in preparation for covalent attachment; (ii) to spatially position the two cysteinyl sulfurs adjacent to the two heme vinyl groups for thioether formation; and (iii) to aid in release of the holocytochrome c from the HCCS active site. Only H19M is able to carry out these three roles, albeit at lower efficiencies than the natural His-19.

  9. Mechanisms of Mitochondrial Holocytochrome c Synthase and the Key Roles Played by Cysteines and Histidine of the Heme Attachment Site, Cys-XX-Cys-His*

    PubMed Central

    Babbitt, Shalon E.; San Francisco, Brian; Mendez, Deanna L.; Lukat-Rodgers, Gudrun S.; Rodgers, Kenton R.; Bretsnyder, Eric C.; Kranz, Robert G.

    2014-01-01

    Mitochondrial cytochrome c assembly requires the covalent attachment of heme by thioether bonds between heme vinyl groups and a conserved CXXCH motif of cytochrome c/c1. The enzyme holocytochrome c synthase (HCCS) binds heme and apocytochrome c substrate to catalyze this attachment, subsequently releasing holocytochrome c for proper folding to its native structure. We address mechanisms of assembly using a functional Escherichia coli recombinant system expressing human HCCS. Human cytochrome c variants with individual cysteine, histidine, double cysteine, and triple cysteine/histidine substitutions (of CXXCH) were co-purified with HCCS. Single and double mutants form a complex with HCCS but not the triple mutant. Resonance Raman and UV-visible spectroscopy support the proposal that heme puckering induced by both thioether bonds facilitate release of holocytochrome c from the complex. His-19 (of CXXCH) supplies the second axial ligand to heme in the complex, the first axial ligand was previously shown to be from HCCS residue His-154. Substitutions of His-19 in cytochrome c to seven other residues (Gly, Ala, Met, Arg, Lys, Cys, and Tyr) were used with various approaches to establish other roles played by His-19. Three roles for His-19 in HCCS-mediated assembly are suggested: (i) to provide the second axial ligand to the heme iron in preparation for covalent attachment; (ii) to spatially position the two cysteinyl sulfurs adjacent to the two heme vinyl groups for thioether formation; and (iii) to aid in release of the holocytochrome c from the HCCS active site. Only H19M is able to carry out these three roles, albeit at lower efficiencies than the natural His-19. PMID:25170082

  10. Implications for the North American Lower Crustal 7.xx km/s Layer from an Exhumed Crustal Root, Western Canadian Shield

    NASA Astrophysics Data System (ADS)

    Johnson, Calvin Everette, Jr.

    Lactic acid is widely existing in human bodies, animals and microorganisms. Recently, using biosensor to detect the concentration of lactic acid and diagnose disease have attracted great research and development interests. Nanocomposites is one of the best material used for biosensor because their wonderful conductivity, optical and electrochemical properties. In the study, MoS2 and polypyrrole (PPY) are used for the composite material electrode. To determine whether lactate oxidase (LOD) was helpful for the biosensor's detective properties, both PPY-MoS2 film with LOD and PPY-MoS2 film without LOD are being tested. The fourier transform infrared spectroscopy (FTIR) and Raman spectroscopic techniques have been used to understand the chemical bonds in the nanocomposite film. The X-ray diffraction (XRD) technique has been performed to understand the crystallographic structure of the MoS 2 -PPY film. The morphologies were confirmed by scanning electron microscopy (SEM). The UV-vis spectroscopy has been used to determine the band structure of composite film. Cyclic voltammetry (CV), chronoamperometry (CA), and electrochemical impedance spectroscopy (EIS) were used to analyze in different concentration of solution, under different scan rate to obtain stability and work efficiency. These results were compared with PPY-MoS2 film with and without lactate oxidase conditions. The chronoamperometric technique has been used to detect the concentration of lactic acid.

  11. The structure and unconventional dihydrogen bonding of a pressure-stabilized hydrogen-rich (NH3BH3)(H2)x(x = 1.5) compound

    DOE PAGES

    Lin, Yu; Welchman, Evan; Thonhauser, Timo; ...

    2017-03-15

    Combining X-ray diffraction, Raman spectroscopy, and ab initio simulations we characterize an extremely hydrogen-rich phase with the chemical formula (NH3BH3)(H2)x (x = 1.5). This phase was formed by compressing ammonia borane (AB, NH3BH3) in an environment with an excess of molecular hydrogen (H2). This compound can store a total of 26.8 wt% hydrogen, both as molecular hydrogen and chemically bonded hydrogen in AB, making it one of the most hydrogen-rich solids currently known. The new compound possesses a layered AB structure where additional H2 molecules reside in channels created through the weaving of AB layers. The unconventional dihydrogen bonding networkmore » of the new compound is significantly modified from its parent AB phase and contains H•••H contacts between adjacent AB molecules and between AB and H2 molecules. H–H can be either a proton donor or a proton acceptor that forms new types of dihydrogen bonding with the host AB molecules, which are depicted as H–H•••H–B or H–H•••H–N, respectively. Furthermore, this study not only demonstrates the strategy and the promise of using pressure for new material synthesis, but also unleashes the power of combining experiments and ab initio calculations for elucidating novel structures and unusual bonding configurations in dense low-Z materials.« less

  12. Unique unbalanced X;X translocation (Xq22;p11.2) in a woman with primary amenorrhea but without Ullrich-Turner syndrome.

    PubMed

    Letterie, G S

    1995-12-04

    This is a report of a patient with delayed puberty and a previously unreported translocation 46,X -X, +der(X),t(X;X) (q22;p11.2) without any manifestations of Ullrich-Turner syndrome. The relationship of this unbalanced translocation to the critical region hypothesis is discussed.

  13. [Studies on arsenic metabolism (XX). Arsenic accumulation in the organs and excretion into the feces and urine of rats chronically poisoned with arsenic (author's transl)].

    PubMed

    Tamura, S

    1977-11-01

    Male and female rats (60 approximately 80 g) of Wistar strain were randomly divided into two groups and were given milk and cereal diets, respectively. Each group was further divided into two groups; one was given the diet containing 100ppm of arsenic trioxide and the other a diet containing "arsenic compound" (100ppm as arsenic trioxide). Each group included five rats of both sexes. A 6-month feeding of the test diet was followed by provision of a normal diet. The accumulated arsenic was excreted almost 100% from the brain and 20 approximately 30% from organs such as kidney, liver, spleen and lung. The arsenic level persisted in tissues in animals on the cereal diet, as compared with those fed the milk diet. There was no significant difference in the accumulation and excretion of arsenic between the groups given arsenic trioxide or "arsenic compound".

  14. Transiting exoplanets from the CoRoT space mission. XX. CoRoT-20b: A very high density, high eccentricity transiting giant planet

    NASA Astrophysics Data System (ADS)

    Deleuil, M.; Bonomo, A. S.; Ferraz-Mello, S.; Erikson, A.; Bouchy, F.; Havel, M.; Aigrain, S.; Almenara, J.-M.; Alonso, R.; Auvergne, M.; Baglin, A.; Barge, P.; Bordé, P.; Bruntt, H.; Cabrera, J.; Carpano, S.; Cavarroc, C.; Csizmadia, Sz.; Damiani, C.; Deeg, H. J.; Dvorak, R.; Fridlund, M.; Hébrard, G.; Gandolfi, D.; Gillon, M.; Guenther, E.; Guillot, T.; Hatzes, A.; Jorda, L.; Léger, A.; Lammer, H.; Mazeh, T.; Moutou, C.; Ollivier, M.; Ofir, A.; Parviainen, H.; Queloz, D.; Rauer, H.; Rodríguez, A.; Rouan, D.; Santerne, A.; Schneider, J.; Tal-Or, L.; Tingley, B.; Weingrill, J.; Wuchterl, G.

    2012-02-01

    We report the discovery by the CoRoT space mission of a new giant planet, CoRoT-20b. The planet has a mass of 4.24 ± 0.23 MJup and a radius of 0.84 ± 0.04 RJup. With a mean density of 8.87 ± 1.10 g cm-3, it is among the most compact planets known so far. Evolutionary models for the planet suggest a mass of heavy elements of the order of 800 M⊕ if embedded in a central core, requiring a revision either of the planet formation models or both planet evolution and structure models. We note however that smaller amounts of heavy elements are expected by more realistic models in which they are mixed throughout the envelope. The planet orbits a G-type star with an orbital period of 9.24 days and an eccentricity of 0.56.The star's projected rotational velocity is vsini = 4.5 ± 1.0 km s-1, corresponding to a spin period of 11.5 ± 3.1 days if its axis of rotation is perpendicular to the orbital plane. In the framework of Darwinian theories and neglecting stellar magnetic breaking, we calculate the tidal evolution of the system and show that CoRoT-20b is presently one of the very few Darwin-stable planets that is evolving toward a triple synchronous state with equality of the orbital, planetary and stellar spin periods. The CoRoT space mission, launched on December 27th 2006, has been developed and is operated by CNES, with the contribution of Austria, Belgium, Brazil, ESA (RSSD and Science Programme), Germany, and Spain.

  15. Comparative anatomy of female genitalia of generic-level taxa in tribe Aedini (Diptera: Culicidae). Part XX. Genus Rampamyia Reinert, Harbach and Kitching.

    USDA-ARS?s Scientific Manuscript database

    A comparative, morphological analysis of the female genitalia of the genus Rampamyia was conducted. The female genitalia of the genus are characterized and a comparison with other taxa is provided. The type species of the genus, Ra. notoscripta (Skuse), is illustrated. Treatment of the genital mo...

  16. Resultados de una encuesta sobre posibles reformas ortograficas en el espanol del siglo XX (Results of a Survey Concerning Possible Orthographic Reforms in Twentieth Century Spanish)

    ERIC Educational Resources Information Center

    Varela Cuellar, Beatriz

    1976-01-01

    This article presents the results of a questionnaire sent to Spanish teachers regarding possible orthographic reforms in Spanish. Changes considered included elimination of certain letters and representation of each phoneme by only one letter. Responses to each question are classified and explained. (Text is in Spanish.) (CHK)

  17. The SAURON project - XX. The Spitzer [3.6] - [4.5] colour in early-type galaxies: colours, colour gradients and inverted scaling relations

    NASA Astrophysics Data System (ADS)

    Peletier, Reynier F.; Kutdemir, Elif; van der Wolk, Guido; Falcón-Barroso, Jesús; Bacon, Roland; Bureau, Martin; Cappellari, Michele; Davies, Roger L.; de Zeeuw, P. Tim; Emsellem, Eric; Krajnović, Davor; Kuntschner, Harald; McDermid, Richard M.; Sarzi, Marc; Scott, Nicholas; Shapiro, Kristen L.; van den Bosch, Remco C. E.; van de Ven, Glenn

    2012-01-01

    We investigate the [3.6]-[4.5] Spitzer-IRAC colour behaviour of the early-type galaxies of the SAURON survey, a representative sample of 48 nearby ellipticals and lenticulars. We investigate how this colour, which is unaffected by dust extinction, can be used to constrain the stellar populations in these galaxies. We find a tight relation between the [3.6]-[4.5] colour and effective velocity dispersion, a good mass indicator in early-type galaxies: ([3.6]-[4.5])e = (-0.109 ? 0.007)?+ (0.154 ? 0.016). Contrary to other colours in the optical and near-infrared, we find that the colours become bluer for larger galaxies. The relations are tighter when using the colour inside re (scatter 0.013 mag), rather than the much smaller re/8 aperture (scatter 0.023 mag), due to the presence of young populations in the central regions. We also obtain strong correlations between the [3.6]-[4.5] colour and three strong absorption lines (H?, Mgb and Fe 5015). Comparing our data with the models of Marigo et al., which show that more metal rich galaxies are bluer, we can explain our results in a way consistent with results from the optical, by stating that larger galaxies are more metal rich. The blueing is caused by a strong CO absorption band, whose line strength increases strongly with decreasing temperature and which covers a considerable fraction of the 4.5-?m filter. In galaxies that contain a compact radio source, the [3.6]-[4.5] colour is generally slightly redder (by 0.015 ? 0.007 mag using the re/8 aperture) than in the other galaxies, indicating small amounts of either hot dust, non-thermal emission, or young stars near the centre. We find that the large majority of the galaxies show redder colours with increasing radius. Removing the regions with evidence for young stellar populations (from the H? absorption line) and interpreting the colour gradients as metallicity gradients, we find that our galaxies are more metal poor going outwards. The radial [3.6]-[4.5] gradients correlate very well with the metallicity gradients derived from optical line indices. We do not find any correlation between the gradients and galaxy mass; at every mass, galaxies display a real range in metallicity gradients. Consistent with our previous work on line indices, we find a tight relation between local [3.6]-[4.5] colour and local escape velocity. The small scatter from galaxy to galaxy, although not negligible, shows that the amount and distribution of the dark matter relative to the visible light cannot be too different from galaxy to galaxy. Due to the lower sensitivity of the [3.6]-[4.5] colour to young stellar populations, this relation is more useful to infer the galaxy potential than the Mgb-vesc relation.

  18. Resultados de una encuesta sobre posibles reformas ortograficas en el espanol del siglo XX (Results of a Survey Concerning Possible Orthographic Reforms in Twentieth Century Spanish)

    ERIC Educational Resources Information Center

    Varela Cuellar, Beatriz

    1976-01-01

    This article presents the results of a questionnaire sent to Spanish teachers regarding possible orthographic reforms in Spanish. Changes considered included elimination of certain letters and representation of each phoneme by only one letter. Responses to each question are classified and explained. (Text is in Spanish.) (CHK)

  19. Sirenomelia: a review on embryogenic enviromental theories, novel three-dimensional ultrasound imaging and first trimester diagnosis in a case of mosaic 69,XXX/46,XX fetus.

    PubMed

    Tonni, Gabriele; Gabriele, Tonni; Grisolia, Gianpaolo; Gianpaolo, Grisolia

    2013-07-01

    Sirenomelia is caused by atrophy of the lower extremities that is commonly associated with gastrointestinal and urogenital malformations. Embryogenic environmental theories and systematic review of the literature are reported. Genetic basis of the condition has been demonstrated in the animal model. In humans, association with de novo balanced translocation has only recently been documented. A case of triploidy mosaic fetus with sirenomelia and posterior fossa anomaly diagnosed at first trimester using novel three-dimensional ultrasound imaging techniques is presented.

  20. Innovative Features of Comparative-Historical Research of European and Azerbaijani Cultural Heritage (Based on the Materials of British and Azerbaijani Literature of the XX Century)

    ERIC Educational Resources Information Center

    Eugster, Nicolas; Hasanov, Elnur L.

    2016-01-01

    The beginning of the twentieth century is characterized as a period of formation of literary prose in Azerbaijan literature, which reminds already formed a new type of British prose. These new development trends appeared in plot, content, style, the world of characters, artistic-philosophical thought as well as in narrative features. The genre of…