78 FR 60264 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-01

...), specialties and skills relevant to their job, and duty limitations relevant to job requirements. Authority for... demilitarized zone (DMZ). Audits of user activity will be conducted on a periodic basis. Retention and disposal...

7 CFR 220.9 - Reimbursement payments.

Code of Federal Regulations, 2014 CFR

2014-01-01

... breakfasts meeting the requirements of § 220.8, and reported in accordance with § 220.11(b) of this part. School Food Authorities shall plan for and prepare breakfasts on the basis of participation trends, with...

7 CFR 220.9 - Reimbursement payments.

Code of Federal Regulations, 2011 CFR

2011-01-01

... breakfasts meeting the requirements of § 220.8, and reported in accordance with § 220.11(b) of this part. School Food Authorities shall plan for and prepare breakfasts on the basis of participation trends, with...

7 CFR 220.9 - Reimbursement payments.

Code of Federal Regulations, 2010 CFR

2010-01-01

... breakfasts meeting the requirements of § 220.8, and reported in accordance with § 220.11(b) of this part. School Food Authorities shall plan for and prepare breakfasts on the basis of participation trends, with...

7 CFR 220.9 - Reimbursement payments.

Code of Federal Regulations, 2012 CFR

2012-01-01

... breakfasts meeting the requirements of § 220.8, and reported in accordance with § 220.11(b) of this part. School Food Authorities shall plan for and prepare breakfasts on the basis of participation trends, with...

7 CFR 220.9 - Reimbursement payments.

Code of Federal Regulations, 2013 CFR

2013-01-01

... breakfasts meeting the requirements of § 220.8, and reported in accordance with § 220.11(b) of this part. School Food Authorities shall plan for and prepare breakfasts on the basis of participation trends, with...

Moving beyond the Page in Content Area Literacy: Comprehension Instruction for Multimodal Texts in Science

ERIC Educational Resources Information Center

Wilson, Amy Alexandra

2008-01-01

Using a science lesson on lunar phases as a basis for discussion, the author suggests ways that teachers can provide literacy instruction on multimodal texts in science. The author asserts that multiple representations are central to the discipline of science, and that students require explicit instruction on how to critically read, evaluate, and…

7 CFR 1486.507 - What is the effect of failing to make required contributions?

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false What is the effect of failing to make required... MARKETS PROGRAM Reporting, Evaluation, and Compliance § 1486.507 What is the effect of failing to make... percentage basis, the original ratio of private contributions to the authorized EMP funding level. ...

7 CFR 1486.507 - What is the effect of failing to make required contributions?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false What is the effect of failing to make required... MARKETS PROGRAM Reporting, Evaluation, and Compliance § 1486.507 What is the effect of failing to make... percentage basis, the original ratio of private contributions to the authorized EMP funding level. ...

Taxation--Rejection of the "Public Purpose" Requirement for State Tax Exemption--In re University of North Carolina.

ERIC Educational Resources Information Center

Massey, David Sanders

1981-01-01

The origin of the "public purpose" requirement in North Carolina and the contrary authority exempting property from taxation solely on the basis of state ownership is examined. The North Carolina Supreme Court declared exemptions for "public purposes" unconstitutional. (Available from: Wake Forest University School of Law,…

38 CFR 3.314 - Basic pension determinations.

Code of Federal Regulations, 2010 CFR

2010-07-01

... therefor are: (1) Claims based on service of less than 90 days in the Spanish-American War require a rating.... (Authority: 38 U.S.C. 1512) (2) Veterans entitled to pension on the basis of service in the Spanish-American...

Library Services to University Branch Campuses: The Ohio State Experience

ERIC Educational Resources Information Center

Schmidt, C. James; And Others

1970-01-01

The Ohio State University Main Library acquires and processes books, on a cost-supported contract basis, for each of four regional campus undergraduate libraries. The article describes requirements, rationale, and procedures, and diagrams procedural flow. (Author/NH)

38 CFR 49.46 - Procurement records.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Post-Award Requirements Procurement Standards § 49.46... of competition when competitive bids or offers are not obtained, and (c) Basis for award cost or price. (Authority: Pub. L. 104-156; 110 Stat. 1396) ...

A Clash of Cultures: Improving the "Fit" between Evaluative Independence and the Political Requirements of a Democratic Society

ERIC Educational Resources Information Center

Chelimsky, Eleanor

2008-01-01

This article presents a plenary address wherein the author talks about cultural clashes, about what happens when evaluation meets politics. In her address, the author talks about the kinds of clashes that occur on a regular basis between evaluative independence and the political culture it challenges, along with possible ways to predict, parry, or…

5 CFR 335.101 - Effect of position change on status and tenure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... and tenure. (a) Status. A position change authorized by § 335.102 does not change the competitive... under chapter 45 of title 39, United States Code, or required by law to be filled on a permanent basis... paid under chapter 45 of title 39, United States Code, or required by law to be filled on a permanent...

5 CFR 335.101 - Effect of position change on status and tenure.

Code of Federal Regulations, 2011 CFR

2011-01-01

... and tenure. (a) Status. A position change authorized by § 335.102 does not change the competitive... under chapter 45 of title 39, United States Code, or required by law to be filled on a permanent basis... paid under chapter 45 of title 39, United States Code, or required by law to be filled on a permanent...

41 CFR 61-250.11 - On what form must the data required by this part be submitted?

Code of Federal Regulations, 2011 CFR

2011-07-01

.... LEGAL BASIS FOR REPORTING REQUIREMENTS Title 38, United States Code, Section 4212(d) and PL 105-339... authorized). For the existing employees, the numbers of veterans within these three groups are to be broken... number of veteran new hires in each of the three groups above is to be reported, along with the total...

DARHT: INTEGRATION OF AUTHORIZATION BASIS REQUIREMENTS AND WORKER SAFETY

DOE Office of Scientific and Technical Information (OSTI.GOV)

D. A. MC CLURE; C. A. NELSON; R. L. BOUDRIE

2001-04-01

This document describes the results of consensus agreements reached by the DARHT Safety Planning Team during the development of the update of the DARHT Safety Analysis Document (SAD). The SAD is one of the Authorization Basis (AB) Documents required by the Department prior to granting approval to operate the DARHT Facility. The DARHT Safety Planning Team is lead by Mr. Joel A. Baca of the Department of Energy Albuquerque Operations Office (DOE/AL). Team membership is drawn from the Department of Energy Albuquerque Operations Office, the Department of Energy Los Alamos Area Office (DOE/LAAO), and several divisions of the Los Alamosmore » National Laboratory. Revision 1 of the DARHT SAD had been written as part of the process for gaining approval to operate the Phase 1 (First Axis) Accelerator. Early in the planning stage for the required update of the SAD for the approval to operate both Phase 1 and Phase 2 (First Axis and Second Axis) DARHT Accelerator, it was discovered that a conflict existed between the Laboratory approach to describing the management of facility and worker safety.« less

Data sets for author name disambiguation: an empirical analysis and a new resource.

PubMed

Müller, Mark-Christoph; Reitz, Florian; Roy, Nicolas

2017-01-01

Data sets of publication meta data with manually disambiguated author names play an important role in current author name disambiguation (AND) research. We review the most important data sets used so far, and compare their respective advantages and shortcomings. From the results of this review, we derive a set of general requirements to future AND data sets. These include both trivial requirements, like absence of errors and preservation of author order, and more substantial ones, like full disambiguation and adequate representation of publications with a small number of authors and highly variable author names. On the basis of these requirements, we create and make publicly available a new AND data set, SCAD-zbMATH. Both the quantitative analysis of this data set and the results of our initial AND experiments with a naive baseline algorithm show the SCAD-zbMATH data set to be considerably different from existing ones. We consider it a useful new resource that will challenge the state of the art in AND and benefit the AND research community.

32 CFR 728.80 - U.S. Government employees.

Code of Federal Regulations, 2012 CFR

2012-07-01

... National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY PERSONNEL MEDICAL AND DENTAL CARE..., exclusive of nervous, mental, or contagious diseases or those requiring domiciliary care. Routine dental care, other than dental prosthesis and orthodontia, is authorized on a space available basis provided...

32 CFR 728.79 - Employees of Federal contractors and subcontractors.

Code of Federal Regulations, 2010 CFR

2010-07-01

... PERSONNEL MEDICAL AND DENTAL CARE FOR ELIGIBLE PERSONS AT NAVY MEDICAL DEPARTMENT FACILITIES Other Persons... nervous, mental, or contagious diseases or those requiring domiciliary care. Routine dental care, other than dental prosthesis and orthodontia, is authorized on a space available basis provided facilities...

32 CFR 728.79 - Employees of Federal contractors and subcontractors.

Code of Federal Regulations, 2012 CFR

2012-07-01

... PERSONNEL MEDICAL AND DENTAL CARE FOR ELIGIBLE PERSONS AT NAVY MEDICAL DEPARTMENT FACILITIES Other Persons... nervous, mental, or contagious diseases or those requiring domiciliary care. Routine dental care, other than dental prosthesis and orthodontia, is authorized on a space available basis provided facilities...

32 CFR 728.80 - U.S. Government employees.

Code of Federal Regulations, 2010 CFR

2010-07-01

... National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY PERSONNEL MEDICAL AND DENTAL CARE..., exclusive of nervous, mental, or contagious diseases or those requiring domiciliary care. Routine dental care, other than dental prosthesis and orthodontia, is authorized on a space available basis provided...

32 CFR 728.80 - U.S. Government employees.

Code of Federal Regulations, 2011 CFR

2011-07-01

... National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY PERSONNEL MEDICAL AND DENTAL CARE..., exclusive of nervous, mental, or contagious diseases or those requiring domiciliary care. Routine dental care, other than dental prosthesis and orthodontia, is authorized on a space available basis provided...

32 CFR 728.80 - U.S. Government employees.

Code of Federal Regulations, 2013 CFR

2013-07-01

... National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY PERSONNEL MEDICAL AND DENTAL CARE..., exclusive of nervous, mental, or contagious diseases or those requiring domiciliary care. Routine dental care, other than dental prosthesis and orthodontia, is authorized on a space available basis provided...

32 CFR 728.79 - Employees of Federal contractors and subcontractors.

Code of Federal Regulations, 2011 CFR

2011-07-01

... PERSONNEL MEDICAL AND DENTAL CARE FOR ELIGIBLE PERSONS AT NAVY MEDICAL DEPARTMENT FACILITIES Other Persons... nervous, mental, or contagious diseases or those requiring domiciliary care. Routine dental care, other than dental prosthesis and orthodontia, is authorized on a space available basis provided facilities...

32 CFR 728.79 - Employees of Federal contractors and subcontractors.

Code of Federal Regulations, 2013 CFR

2013-07-01

... PERSONNEL MEDICAL AND DENTAL CARE FOR ELIGIBLE PERSONS AT NAVY MEDICAL DEPARTMENT FACILITIES Other Persons... nervous, mental, or contagious diseases or those requiring domiciliary care. Routine dental care, other than dental prosthesis and orthodontia, is authorized on a space available basis provided facilities...

31 CFR 33.100 - Basis and purpose.

Code of Federal Regulations, 2012 CFR

2012-07-01

....100 Money and Finance: Treasury Office of the Secretary of the Treasury WAIVERS FOR STATE INNOVATION... for State Innovation, which the Secretary may authorize for plan years beginning on or after January 1.... (b) Purpose. This part sets forth certain procedural requirements for Waivers for State Innovation...

31 CFR 33.100 - Basis and purpose.

Code of Federal Regulations, 2014 CFR

2014-07-01

....100 Money and Finance: Treasury Office of the Secretary of the Treasury WAIVERS FOR STATE INNOVATION... for State Innovation, which the Secretary may authorize for plan years beginning on or after January 1.... (b) Purpose. This part sets forth certain procedural requirements for Waivers for State Innovation...

31 CFR 33.100 - Basis and purpose.

Code of Federal Regulations, 2013 CFR

2013-07-01

....100 Money and Finance: Treasury Office of the Secretary of the Treasury WAIVERS FOR STATE INNOVATION... for State Innovation, which the Secretary may authorize for plan years beginning on or after January 1.... (b) Purpose. This part sets forth certain procedural requirements for Waivers for State Innovation...

Aviation Ground Accidents: The Requirements for Cost Impact Data.

ERIC Educational Resources Information Center

King, Frank H.

1983-01-01

Aviation accidents are costly, whether they occur in the air or on the ground. Precise information regarding the cost of ground accidents is important, but not easily available on an industry-wide basis. This article points up the need for information on ground accident costs. (Author)

32 CFR 185.4 - Policy.

Code of Federal Regulations, 2014 CFR

2014-07-01

... non-reimbursable basis only if required by law or if both authorized by law and approved by the... perform its primary mission). (f) DSCA plans shall be compatible with the National Response Framework; the... necessary to restore governmental function and public order, or, (2) When duly constituted Federal, State...

48 CFR 432.407 - Interest.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Interest. 432.407 Section... REQUIREMENTS CONTRACT FINANCING Advance Payments for Non-Commercial Items 432.407 Interest. (a) The HCA is designated as the individual who may authorize, on a case by case basis, advance payments without interest...

48 CFR 432.407 - Interest.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Interest. 432.407 Section... REQUIREMENTS CONTRACT FINANCING Advance Payments for Non-Commercial Items 432.407 Interest. (a) The HCA is designated as the individual who may authorize, on a case by case basis, advance payments without interest...

48 CFR 432.407 - Interest.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Interest. 432.407 Section... REQUIREMENTS CONTRACT FINANCING Advance Payments for Non-Commercial Items 432.407 Interest. (a) The HCA is designated as the individual who may authorize, on a case by case basis, advance payments without interest...

48 CFR 432.407 - Interest.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Interest. 432.407 Section... REQUIREMENTS CONTRACT FINANCING Advance Payments for Non-Commercial Items 432.407 Interest. (a) The HCA is designated as the individual who may authorize, on a case by case basis, advance payments without interest...

48 CFR 432.407 - Interest.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Interest. 432.407 Section... REQUIREMENTS CONTRACT FINANCING Advance Payments for Non-Commercial Items 432.407 Interest. (a) The HCA is designated as the individual who may authorize, on a case by case basis, advance payments without interest...

Teaching social justice.

PubMed

Fahrenwald, Nancy L

2003-01-01

Social justice is a core nursing value and the foundation of public health nursing. Social justice ideology requires nursing students to uphold moral, legal, and humanistic principles related to health. As such, teaching social justice requires a basis in moral developmental theory. In addition, teaching social justice demands action beyond classroom pedagogy. The author describes how social justice is taught within a baccalaureate program. A social justice project is described and examples are provided.

Orbital transfer vehicle concept definition and system analysis study. Volume 2: OTV concept definition and evaluation. Book 1: Mission and system requirements

NASA Technical Reports Server (NTRS)

Kofal, Allen E.

1987-01-01

The mission and system requirements for the concept definition and system analysis of the Orbital Transfer Vehicle (OTV) are established. The requirements set forth constitute the single authority for the selection, evaluation, and optimization of the technical performance and design of the OTV. This requirements document forms the basis for the Ground and Space Based OTV concept definition analyses and establishes the physical, functional, performance and design relationships to STS, Space Station, Orbital Maneuvering Vehicle (OMV), and payloads.

[Critical analysis of requirements for scientific assessment as a basis for good governance: case of the chikungunya epidemic on Reunion Island and Mayotte in 2005 and 2006].

PubMed

Colom, J

2012-03-01

The constitutional precautionary principle as applied in laws governing health care at the community level requires rigorous scientific assessment. The goal of this assessment is to provide authorities with sound evidence as a basis for implementing precautionary measures in function of degree of risk and other parameters such as the level of public health protection that is high in the EU. As the political authority, the government can act independently of conclusions issued by scientific commissions provided that the commission's level of expertise meets national and European standards and that research methodology and findings are consistent with scientific data published in the international literature. These requirements were not meet for the chikungunya pandemic that struck France on Reunion Island and Mayotte from 2004 to 2006. This epidemic that was preceded by many outbreaks in Indonesia between 2001 and 2003 began in Africa and then swept across the Indian Ocean to India and Asia. After an overview of the scientific assessment, this article raises arguments supporting possible allegations of gross misgovernance by the state and experts.

Legalization of Employment Discrimination against White Males.

ERIC Educational Resources Information Center

Fontham, Michael R.

1978-01-01

The intervention of government to require speeial treatment of designated groups on the basis of race, color, or sex is inconsistent with principles of equal treatment under American law. Regardless of past discrimination against certain classes, governmental determination to favor them at the expense of White males is not justified. (Author/WI)

Hierarchical Task Analysis and Training Decisions.

ERIC Educational Resources Information Center

Shepherd, A.

1985-01-01

Hierarchical task analysis (HTA), which requires description of a task in terms of a hierarchy of operations and plans, is reviewed and examined as a basis for making training decisions. Benefits of HTA in terms of economy of analysis and as a means of accounting for complex performance are outlined. (Author/MBR)

7 CFR 2.88 - Assistant Secretary for Civil Rights.

Code of Federal Regulations, 2011 CFR

2011-01-01

... on the basis of sex in USDA education programs and activities funded by the Department. (iv) Actions... title relating to compliance by “other means authorized by law.” (11) Make determinations required by... appropriate. (12) Make determinations that program complaint investigations performed under § 15.6 of this...

7 CFR 2.88 - Assistant Secretary for Civil Rights.

Code of Federal Regulations, 2012 CFR

2012-01-01

... on the basis of sex in USDA education programs and activities funded by the Department. (iv) Actions... title relating to compliance by “other means authorized by law.” (11) Make determinations required by... appropriate. (12) Make determinations that program complaint investigations performed under § 15.6 of this...

5 CFR 2423.26 - Stipulations of fact submissions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... required and must be submitted within 30 days of the joint motion. Upon receipt of the briefs, such motions... motion and decide the case through stipulation. (c) Stipulations to the Authority. Where the stipulation provides an adequate basis for application of established precedent and a decision by the Administrative...

38 CFR 36.4352 - Authority to close loans on the automatic basis.

Code of Federal Regulations, 2010 CFR

2010-07-01

... reviewed and approved by the underwriter. (4) Financial requirements. Each application must include the most recent annual financial statement audited and certified by a certified public accountant (CPA). If the date of the annual financial statement precedes that of the application by more than six months...

Annual Status Report (FY2017): Performance Assessment for the Environmental Restoration Disposal Facility.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nichols, Will E.

In accordance with U.S. Department of Energy (DOE) requirements in DOE O 435.1 Chg 11 and DOE M 435.1-1 Chg 1,2 a determination of continued adequacy of the performance assessment (PA), composite analysis (CA), and disposal authorization statement (DAS) is required on an annual basis. This determination must consider the results of data collection and analysis from research, field studies, and monitoring.

Using resources for scientific-driven pharmacovigilance: from many product safety documents to one product safety master file.

PubMed

Furlan, Giovanni

2012-08-01

Current regulations require a description of the overall safety profile or the specific risks of a drug in multiple documents such as the Periodic and Development Safety Update Reports, Risk Management Plans (RMPs) and Signal Detection Reports. In a resource-constrained world, the need for preparing multiple documents reporting the same information results in shifting the focus from a thorough scientific and medical evaluation of the available data to maintaining compliance with regulatory timelines. Since the aim of drug safety is to understand and characterize product issues to take adequate risk minimization measures rather than to comply with bureaucratic requirements, there is the need to avoid redundancy. In order to identify core drug safety activities that need to be undertaken to protect patient safety and reduce the number of documents reporting the results of these activities, the author has reviewed the main topics included in the drug safety guidelines and templates. The topics and sources that need to be taken into account in the main regulatory documents have been found to greatly overlap and, in the future, as a result of the new Periodic Safety Update Report structure and requirements, in the author's opinion this overlap is likely to further increase. Many of the identified inter-document differences seemed to be substantially formal. The Development Safety Update Report, for example, requires separate presentation of the safety issues emerging from different sources followed by an overall evaluation of each safety issue. The RMP, instead, requires a detailed description of the safety issues without separate presentation of the evidence derived from each source. To some extent, however, the individual documents require an in-depth analysis of different aspects; the RMP, for example, requires an epidemiological description of the indication for which the drug is used and its risks. At the time of writing this article, this is not specifically required by other documents. The author has identified signal detection (intended not only as adverse event disproportionate reporting, but including non-clinical, laboratory, clinical analysis data and literature screening) and characterization as the basis for the preparation of all drug safety documents, which can be viewed as different ways of presenting the results of this activity. Therefore, the author proposes to merge all the aggregate reports required by current regulations into a single document - the Drug Safety Master File. This report should contain all the available information, from any source, regarding the potential and identified risks of a drug. It should be a living document updated and submitted to regulatory authorities on an ongoing basis.

Teaching Business Ethics: A Quandary for Accounting Educators

ERIC Educational Resources Information Center

Frank, Gary; Ofobike, Emeka; Gradisher, Suzanne

2010-01-01

The authors discuss the pressures that accounting educators face in meeting expectations to include ethics in the accounting curriculum. Most schools still do not require discrete ethics courses for accounting students; ethics coverage is on a course-by-course basis. However, not all professors are equally comfortable or knowledgeable of models of…

Structuring a Competency-Based Accounting Communication Course at the Graduate Level

ERIC Educational Resources Information Center

Sharifi, Mohsen; McCombs, Gary B.; Fraser, Linda Lussy; McCabe, Robert K.

2009-01-01

The authors describe a graduate capstone accounting class as a basis for building communication skills desired by both accounting practitioners and accounting faculty. An academic service-learning (ASL) component is included. Adopted as a required class for a master of science degree in accounting at two universities, this course supports…

Elaborations on the Socioegocentric and Dual-Level Connectionist Models of Group Interaction Processes

ERIC Educational Resources Information Center

Hewes, Dean E.

2009-01-01

The purpose of the author's contribution to this colloquy was to spark conversation on the theoretical nature of communication processes and the evidentiary requirements for testing their relationship to group outcomes. Co-discussants have raised important issues concerning the philosophical basis of the socioegocentric model (SM) and dual-level…

A Student Data Base: An Aid to Student Selection, Program Evaluation, and Management Decision Making

ERIC Educational Resources Information Center

And Others; Maynard, Diane

1974-01-01

The authors outline a proposed student information system incorporating a cross-section of student characteristics to provide a basis for longitudinal analysis and an examination of changes in students. (Data might include standard biographical information, achievement test scores, and information obtained from a required test battery in…

48 CFR 2806.302-70 - Determination and findings.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Determination and findings... Determination and findings. (a) Procedure. The determination and findings (D&F) required by FAR 6.302.7(c)(1... Determination and Findings Authority To Use Other Than Full and Open Competition: Upon the basis of the...

77 FR 24999 - Self-Regulatory Organizations; The Options Clearing Corporation; Notice of Filing and Order...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-26

... operational capacity to effect a settlement with each clearing member, on an intraday basis, either routinely... 1301(c) provides OCC with the authority to effect intraday settlements and Interpretation and Policy .01 of Rule 1301 states OCC's policy of not requiring intraday variation payments while reserving OCC...

Setting Tuition Levels at Public Institutions: The Case of the University of Washington

ERIC Educational Resources Information Center

Johnson, Jane Louise

1976-01-01

Contending that the practice of setting tuition levels on the basis of comparison with other institutions is not appropriate, the author proposes that more attention be given to the state's budgetary needs and tax structure, requiring changed attitudes toward taxes and public services. When this is impossible tuition increases will be necessary.…

[Building questions in forensic medicine and their logical basis].

PubMed

Kovalev, D; Shmarov, K; Ten'kov, D

2015-01-01

The authors characterize in brief the requirements to the correct formulation of the questions posed to forensic medical experts with special reference to the mistakes made in building the questions and the ways to avoid them. This article actually continues the series of publications of the authors concerned with the major logical errors encountered in expert conclusions. Further publications will be dedicated to the results of the in-depth analysis of the logical errors contained in the questions posed to forensic medical experts and encountered in the expert conclusions.

41 CFR 102-5.75 - What circumstances do not establish a basis for authorizing home-to-work transportation for field...

Code of Federal Regulations, 2010 CFR

2010-07-01

... not establish a basis for authorizing home-to-work transportation for field work? 102-5.75 Section 102... (Continued) FEDERAL MANAGEMENT REGULATION GENERAL 5-HOME-TO-WORK TRANSPORTATION Authorizing Home-to-Work Transportation § 102-5.75 What circumstances do not establish a basis for authorizing home-to-work transportation...

Anatomical Basis for Safe and Effective Volumization of the Temple.

PubMed

Breithaupt, Andrew D; Jones, Derek H; Braz, Andre; Narins, Rhoda; Weinkle, Susan

2015-12-01

One of the earliest but often unaddressed signs of facial aging is volume loss in the temple. Treatment of the area can produce satisfying results for both patient and practitioner. Safe injection requires explicit knowledge of the anatomy to avoid complications related to the multitude of vessels that course throughout the region at various depths. The authors aim to detail the anatomy of the area and provide a safe and easy-to-follow method for injection. The authors review the relevant anatomy of the temporal region and its application to cosmetic filler injections. The authors describe an easy-to-follow approach for a safe and effective injection window based on numerous anatomical studies. Injection in this area is not without risk, including potential blindness. The authors review the potential complications and their treatments. Hollowing of the temple is an early sign of aging that, when corrected, can lead to significant patient and practitioner satisfaction. Proper anatomically knowledge is required to avoid potentially severe complications. In this study, the authors present a reliable technique to safely and effectively augment this often undertreated area of the aging face.

An Approach To Using All Location Tagged Numerical Data Sets As Continuous Fields With User-Assigned Continuity As A Basis For User-Driven Data Assimilation

NASA Astrophysics Data System (ADS)

Vernon, F.; Arrott, M.; Orcutt, J. A.; Mueller, C.; Case, J.; De Wardener, G.; Kerfoot, J.; Schofield, O.

2013-12-01

Any approach sophisticated enough to handle a variety of data sources and scale, yet easy enough to promote wide use and mainstream adoption is required to address the following mappings: - From the authored domain of observation to the requested domain of interest; - From the authored spatiotemporal resolution to the requested resolution; and - From the representation of data placed on wide variety of discrete mesh types to the use of that data as a continuos field with a selectable continuity. The Open Geospatial Consortium's (OGC) Reference Model[1] with its direct association with the ISO 19000 series standards provides a comprehensive foundation to represent all data on any type of mesh structure, aka "Discrete Coverages". The Reference Model also provides the specification for the core operations required to utilize any Discrete Coverage. The FEniCS Project[2] provides a comprehensive model for how to represent the Basis Functions on mesh structures as "Degrees of Freedom" to present discrete data as continuous fields with variable continuity. In this talk, we will present the research and development the OOI Cyberinfrastructure Project is pursuing to integrate these approaches into a comprehensive Application Programming Interface (API) to author, acquire and operate on the broad range of data formulation from time series, trajectories and tables through to time variant finite difference grids and finite element meshes.

Natural gas imports and exports. Fourth quarter report, 1998

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-12-31

The Office of Natural Gas and Petroleum Import and Export Activities prepares quarterly reports summarizing the data provided by companies authorized to import or export natural gas. Companies are required, as a condition of their authorizations, to file quarterly reports. This report is for the fourth quarter of 1998 (October through December). Attachment A shows the percentage of takes to maximum firm contract levels and the weighted average per unit price for each of the long-term importers during the five most recent reporting quarters. Attachment B shows volumes and prices of gas purchased by long-term importers and exporters during themore » past 12 months. Attachment C shows volume and price information pertaining to gas imported on a short-term or spot market basis. Attachment D shows the gas exported on a short-term or spot market basis to Canada and Mexico.« less

Natural gas imports and exports. First quarter report, 1998

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The Office of Natural Gas and Petroleum Import and Export Activities prepares quarterly reports summarizing the data provided by companies authorized to import or export natural gas. Companies are required, as a condition of their authorizations, to file quarterly reports. This report is for the first quarter of 1998 (January through March). Attachment A shows the percentage of takes to maximum firm contract levels and the weighted average per unit price for each of the long-term importers during the five most recent reporting quarters. Attachment B shows volumes and prices of gas purchased by long-term importers and exporters during themore » past 12 months. Attachment C shows volume and price information pertaining to gas imported on a short-term or spot market basis. Attachment D shows the gas exported on a short-term or spot market basis to Canada and Mexico.« less

How to manage without being a manager

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sweeney, M.A.

1997-06-01

In the author`s current position at Sandia National Laboratories within the Pulsed Power Sciences Center, much of the author`s time is spent in composing short (one page) technical reports and long (> 20 page) technical contracts and program plans for transmission to the Department of Energy and to upper management and also in reviewing long technical documents for accuracy. A major requirement of these efforts is to complete them on a timely basis, often within a few hours or a few days. In this talk, the author reveals some communication {open_quotes}secrets{close_quotes} that have been learned. The idea behind these twelvemore » {open_quotes}secrets{close_quotes} is to get the answers you, as a nonmanager, need quickly from a manager without creating stress either on your part or the manager`s part.« less

77 FR 37252 - Delegations of Authority for the Office of Housing-Federal Housing Administration (FHA...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-20

... Secretary, Office of Single Family Housing Authority is redelegated, on a nationwide basis, to take all... Authority is redelegated, on a nationwide basis, to take all actions necessary to the conduct of single... redelegated, on a nationwide basis, to take all actions necessary to the conduct of single family housing...

The role of PRA in the safety assessment of VVER Nuclear Power Plants in Ukraine.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kot, C.

1999-05-10

Ukraine operates thirteen (13) Soviet-designed pressurized water reactors, VVERS. All Ukrainian plants are currently operating with annually renewable permits until they update their safety analysis reports (SARs), in accordance with new SAR content requirements issued in September 1995, by the Nuclear Regulatory Authority and the Government Nuclear Power Coordinating Committee of Ukraine. The requirements are in three major areas: design basis accident (DBA) analysis, probabilistic risk assessment (PRA), and beyond design-basis accident (BDBA) analysis. The last two requirements, on PRA and BDBA, are new, and the DBA requirements are an expanded version of the older SAR requirements. The US Departmentmore » of Energy (USDOE), as part of its Soviet-Designed Reactor Safety activities, is providing assistance and technology transfer to Ukraine to support their nuclear power plants (NPPs) in developing a Western-type technical basis for the new SARs. USDOE sponsored In-Depth Safety Assessments (ISAs) are in progress at three pilot nuclear reactor units in Ukraine, South Ukraine Unit 1, Zaporizhzhya Unit 5, and Rivne Unit 1, and a follow-on study has been initiated at Khmenytskyy Unit 1. The ISA projects encompass most areas of plant safety evaluation, but the initial emphasis is on performing a detailed, plant-specific Level 1 Internal Events PRA. This allows the early definition of the plant risk profile, the identification of risk significant accident sequences and plant vulnerabilities and provides guidance for the remainder of the safety assessments.« less

Psychiatric and neuropsychological issues in Marfan syndrome: A critical review of the literature.

PubMed

Gritti, Antonella; Pisano, Simone; Catone, Gennaro; Iuliano, Raffaella; Salvati, Tiziana; Gritti, Paolo

2015-01-01

The cooccurrence of Marfan syndrome and psychiatric disorders has been reported for many years. Furthermore, neuropsychological deficits have been shown to be associated with Marfan syndrome. The aim of the present article is to summarize findings from the sparse studies and case reports available. The results hold clinical and therapeutic implications and suggest that psychological and neuropsychological domains in Marfan syndrome patients should be carefully assessed. In particular, some patients may require specific rehabilitation programs. On this basis, a multidisciplinary approach to Marfan syndrome treatment seems mandatory. © The Author(s) 2015.

A Development Architecture for Serious Games Using BCI (Brain Computer Interface) Sensors

PubMed Central

Sung, Yunsick; Cho, Kyungeun; Um, Kyhyun

2012-01-01

Games that use brainwaves via brain–computer interface (BCI) devices, to improve brain functions are known as BCI serious games. Due to the difficulty of developing BCI serious games, various BCI engines and authoring tools are required, and these reduce the development time and cost. However, it is desirable to reduce the amount of technical knowledge of brain functions and BCI devices needed by game developers. Moreover, a systematic BCI serious game development process is required. In this paper, we present a methodology for the development of BCI serious games. We describe an architecture, authoring tools, and development process of the proposed methodology, and apply it to a game development approach for patients with mild cognitive impairment as an example. This application demonstrates that BCI serious games can be developed on the basis of expert-verified theories. PMID:23202227

A development architecture for serious games using BCI (brain computer interface) sensors.

PubMed

Sung, Yunsick; Cho, Kyungeun; Um, Kyhyun

2012-11-12

Games that use brainwaves via brain-computer interface (BCI) devices, to improve brain functions are known as BCI serious games. Due to the difficulty of developing BCI serious games, various BCI engines and authoring tools are required, and these reduce the development time and cost. However, it is desirable to reduce the amount of technical knowledge of brain functions and BCI devices needed by game developers. Moreover, a systematic BCI serious game development process is required. In this paper, we present a methodology for the development of BCI serious games. We describe an architecture, authoring tools, and development process of the proposed methodology, and apply it to a game development approach for patients with mild cognitive impairment as an example. This application demonstrates that BCI serious games can be developed on the basis of expert-verified theories.

47 CFR 27.20 - Digital television transition education reports.

Code of Federal Regulations, 2010 CFR

2010-10-01

... WCS license authorizations in Block A in the 698-704 MHz and 728-734 MHz bands, Block B in the 704-710 MHz and 734-740 MHz bands, Block E in the 722-728 MHz band, Block C, C1, or C2 in the 746-757 MHz and... requirements of this section—and on a quarterly basis thereafter as specified in paragraph (c) of this section...

"My love-hate relationship": Ethical issues associated with nurses' interactions with industry.

PubMed

Grundy, Quinn

2014-08-01

Ethical issues associated with nurses' interactions with industry have implications for the safety, quality, and cost of healthcare. To date, little work has explored nurse-industry interactions and their associated ethical issues empirically. A phenomenological study was conducted to explore registered nurses' interactions with industry in clinical practice. Five registered nurses working in direct patient care were recruited and individual, in-depth interviews were conducted. The University's Committee on Human Research approved the study. Nurses frequently interacted with industry in their practice and felt ambivalent about these interactions. Nurses described systemic cuts to multiple "goods" central to nursing practice, including patient support, but paradoxically relied on industry resources to deliver these "goods." They relied on a particular conception of trust to navigate these interactions but were left to do so individually on the basis of their experience. Conflicts of interest arose as a result of multiple competing interests, and were frequently mediated through nurses' superiors. Nursing as a profession requires a guiding narrative to aid nurses in interpreting and navigating interactions with industry. A conception of trust that incorporates both the work of caring and attention to social justice could form the basis of these interactions, but would require that nursing take a much more critical stance toward marketing interactions. © The Author(s) 2013.

Prediction of Regulation Reserve Requirements in California ISO Control Area based on BAAL Standard

DOE Office of Scientific and Technical Information (OSTI.GOV)

Etingov, Pavel V.; Makarov, Yuri V.; Samaan, Nader A.

This paper presents new methodologies developed at Pacific Northwest National Laboratory (PNNL) to estimate regulation capacity requirements in the California ISO control area. Two approaches have been developed: (1) an approach based on statistical analysis of actual historical area control error (ACE) and regulation data, and (2) an approach based on balancing authority ACE limit control performance standard. The approaches predict regulation reserve requirements on a day-ahead basis including upward and downward requirements, for each operating hour of a day. California ISO data has been used to test the performance of the proposed algorithms. Results show that software tool allowsmore » saving up to 30% on the regulation procurements cost .« less

Nutrition issues in Codex: health claims, nutrient reference values and WTO agreements: a conference report.

PubMed

Aggett, Peter J; Hathcock, John; Jukes, David; Richardson, David P; Calder, Philip C; Bischoff-Ferrari, Heike; Nicklas, Theresa; Mühlebach, Stefan; Kwon, Oran; Lewis, Janine; Lugard, Maurits J F; Prock, Peter

2012-03-01

Codex documents may be used as educational and consensus materials for member governments. Also, the WTO SPS Agreement recognizes Codex as the presumptive international authority on food issues. Nutrient bioavailability is a critical factor in determining the ability of nutrients to provide beneficial effects. Bioavailability also influences the quantitative dietary requirements that are the basis of nutrient intake recommendations and NRVs. Codex, EFSA and some national regulatory authorities have established guidelines or regulations that will permit several types of health claims. The scientific basis for claims has been established by the US FDA and EFSA, but not yet by Codex. Evidence-based nutrition differs from evidence-based medicine, but the differences are only recently gaining recognition. Health claims on foods may provide useful information to consumers, but many will interpret the information to mean that they can rely upon the food or nutrient to eliminate a disease risk. NRVs are designed to provide a quantitative basis for comparing the nutritive values of foods, helping to illustrate how specific foods fit into the overall diet. The INL-98 and the mean of adult male and female values provide NRVs that are sufficient when used as targets for individual intakes by most adults. WTO recognizes Codex as the primary international authority on food issues. Current regulatory schemes based on recommended dietary allowances are trade restrictive. A substantial number of decisions by the EFSA could lead to violation of WTO agreements.

Disposal of LLW and ILW in Germany - Characterisation and Documentation of Waste Packages with Respect to the Change of Requirements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bandt, G.; Spicher, G.; Steyer, St.

2008-07-01

Since the 1998 termination of LLW and ILW emplacement in the Morsleben repository (ERAM), Germany, the treatment, conditioning and documentation of radioactive waste products and packages have been continued on the basis of the waste acceptance requirements as of 1995, prepared for the Konrad repository near Salzgitter in Lower Saxony, Germany. The resulting waste products and packages are stored in interim storage facilities. Due to the Konrad license issued in 2002 the waste acceptance requirements have to be completed by additional requirements imposed by the licensing authority, e. g. for the declaration of chemical waste package constituents. Therefore, documentation ofmore » waste products and packages which are checked by independent experts and are in parts approved by the responsible authority (Office for Radiation Protection, BfS) up to now will have to be checked again for fulfilling the final waste acceptance requirements prior to disposal. In order to simplify these additional checks, databases are used to ensure an easy access to all known facts about the waste packages. A short balance of the existing waste products and packages which are already checked and partly approved by BfS as well as an overview on the established databases ensuring a fast access to the known facts about the conditioning processes is presented. (authors)« less

[Occupational microclimate. Results and prospects of research].

PubMed

Afanas'eva, R F; Bessonova, N A; Burmistrova, O V; Burmistrov, V M; Losik, T K

2013-01-01

The article covers results of studies conducted over last 15 years and aimed to elaboration of requirements to integral parameters of microclimate at workplace, its evaluation and regulation, prophylactic measures against body overcooling and overheating. The authors present methods to evaluate combined effects of physical factors (noise, vibration, microclimate) and to assess microclimate with consideration of factors determining body thermal load (energy expenditure, duration of stay at workplace, heat insulation of clothes and thermo-physical parameters of its materials). Mathematic models of forecasting cold and heat stress are presented, as well as requirements to heat insulation for individual protective means against cold and methods to calculate it. Regimens of work in heating and cooling conditions are specified. The authors set directions for further studies to define regulation requirements to microclimate on basis of studied patterns of body heat state formation, its evaluation criteria, epidemiologic studies results, specified prophylactic measures against overheating and overcooling with consideration of adaptation, sex, thermo-physical characteristics of individual protective means (special clothes, footwear, gauntlets, headwear).

75 FR 56662 - Proposed Information Collection (Application for Authority To Close Loans on an Automatic Basis...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-16

... DEPARTMENT OF VETERANS AFFAIRS [OMB Control No. 2900-0252] Proposed Information Collection (Application for Authority To Close Loans on an Automatic Basis--Nonsupervised Lenders) Activity: Comment... on an automatic basis. DATES: Written comments and recommendations on the proposed collection of...

Security during the Construction of New Nuclear Power Plants: Technical Basis for Access Authorization and Fitness-For-Duty Requirements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Branch, Kristi M.; Baker, Kathryn A.

A technical letter report to the NRC summarizing the findings of a benchmarking study, literature review, and workshop with experts on current industry standards and expert judgments about needs for security during the construction phase of critical infrastructure facilities in the post-September 11 U.S. context, with a special focus on the construction phase of nuclear power plants and personnel security measures.

Implementing the Defense Business Operations Fund, The Case of the Naval Air Reserve at Point Mugu

DTIC Science & Technology

1993-12-13

the basis of financial operating results. Some examples of unit cost measures that have been established are: * Finance and Accounting service...Methodology And Business Decisions, National Association of Accountants , 1976. COMNAVRESFOR P7100.1A. Subject: Budget and Financial Guidance Manual. Deakin...fulfillment of the requirements for the degree of MASTER OF SCIENCE IN FINANCIAL MANAGEMENT from the NAVAL POSTGRADUATE SCHOOL December 1993 Author

Macrodactyly, syndactyly, and localized gigantism of the forefoot. A case report.

PubMed

Scapinelli, R; Baggio, M E

2005-01-01

On the basis of the observation of a rare case of lipomatous macrodactyly of the foot associated with syndactyly in a young child, the authors analyze the anatomopathologic and therapeutic aspects of the pathology and report the data found in the literature. This disease initially requires careful surveillance of its progression, and use of correct footwear. Surgery is indicated when deformity achieves unacceptable values, both functional and cosmetic, in early childhood.

Steam generator tubes integrity: In-service-inspection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Comby, R.J.

1997-02-01

The author`s approach to tube integrity is in terms of looking for flaws in tubes. The basis for this approach is that no simple rules can be fixed to adopt a universal inspection methodology because of various concepts related to experience, leak acceptance, leak before break approach, etc. Flaw specific management is probably the most reliable approach as a compromise between safety, availability and economic issues. In that case, NDE capabilities have to be in accordance with information required by structural integrity demonstration. The author discusses the types of probes which can be used to search for flaws in additionmore » to the types of flaws which are being sought, with examples of specific analysis experiences. The author also discusses the issue of a reporting level as it relates to avoiding false calls, classifying faults, and allowing for automation in analysis.« less

78 FR 46419 - Proposed Information Collection (Application for Authority To Close Loans on an Automatic Basis...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-31

... DEPARTMENT OF VETERANS AFFAIRS [OMB Control No. 2900-0252] Proposed Information Collection (Application for Authority To Close Loans on an Automatic Basis--Nonsupervised Lenders) Activity: Comment... solicits comments for information needed to authorize nonsupervised lenders to close loans on an automatic...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stickney, R.G.

This report presents the results of a systematic evaluation conducted to identify miscellaneous TWRS facilities, tanks and components with potential needed authorization basis upgrades. It provides the Authorization Basis upgrade plan for those miscellaneous TWRS facilities, tanks and components identified.

Acceleration of the rate of ethanol fermentation by addition of nitrogen in high tannin grain sorghum

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mullins, J.T.; NeSmith, C.C.

1987-01-01

In this communication, the authors show that accelerated rates of ethanol production, comparable to sorghum varieties containing low levels of tannins and to corn, can occur without the removal of the tannins. The basis of the inhibition appears to be a lack of sufficient nitrogen in the mash for protein synthesis required to support an accelerated fermentative metabolism in Saccharomyces. No inhibition of the enzymes used for starch hydrolysis was found.

DNA-based identification of invasive alien species in relation to Canadian federal policy and law, and the basis of rapid-response management.

PubMed

Thomas, Vernon G; Hanner, Robert H; Borisenko, Alex V

2016-11-01

Managing invasive alien species in Canada requires reliable taxonomic identification as the basis of rapid-response management. This can be challenging, especially when organisms are small and lack morphological diagnostic features. DNA-based techniques, such as DNA barcoding, offer a reliable, rapid, and inexpensive toolkit for taxonomic identification of individual or bulk samples, forensic remains, and even environmental DNA. Well suited for this requirement, they could be more broadly deployed and incorporated into the operating policy and practices of Canadian federal departments and should be authorized under these agencies' articles of law. These include Fisheries and Oceans Canada, Canadian Food Inspection Agency, Transport Canada, Environment Canada, Parks Canada, and Health Canada. These efforts should be harmonized with the appropriate provisions of provincial jurisdictions, for example, the Ontario Invasive Species Act. This approach necessitates that a network of accredited, certified laboratories exists, and that updated DNA reference libraries are readily accessible. Harmonizing this approach is vital among Canadian federal agencies, and between the federal and provincial levels of government. Canadian policy and law must also be harmonized with that of the USA when detecting, and responding to, invasive species in contiguous lands and waters. Creating capacity in legislation for use of DNA-based identifications brings the authority to fund, train, deploy, and certify staff, and to refine further developments in this molecular technology.

26 CFR 1.9200-1 - Deduction for motor carrier operating authority.

Code of Federal Regulations, 2010 CFR

2010-04-01

... less within which such 80 percent of the acquired corporation's stock was purchased. The election to... election, Y may allocate to the basis of the authority the amount of X's basis in Y stock that would have... Y makes the election under § 1.9200-1(e)(2), then for purposes of allocating X's basis in Y stock, X...

42 CFR 498.100 - Basis, timing, and authority for reopening an ALJ or Board decision.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION APPEALS PROCEDURES FOR... Law Judges or the Departmental Appeals Board § 498.100 Basis, timing, and authority for reopening an...

Basis for the development of sustainable optimisation indicators for activated sludge wastewater treatment plants in the Republic of Ireland.

PubMed

Gordon, G T; McCann, B P

2015-01-01

This paper describes the basis of a stakeholder-based sustainable optimisation indicator (SOI) system to be developed for small-to-medium sized activated sludge (AS) wastewater treatment plants (WwTPs) in the Republic of Ireland (ROI). Key technical publications relating to best practice plant operation, performance audits and optimisation, and indicator and benchmarking systems for wastewater services are identified. Optimisation studies were developed at a number of Irish AS WwTPs and key findings are presented. A national AS WwTP manager/operator survey was carried out to verify the applied operational findings and identify the key operator stakeholder requirements for this proposed SOI system. It was found that most plants require more consistent operational data-based decision-making, monitoring and communication structures to facilitate optimised, sustainable and continuous performance improvement. The applied optimisation and stakeholder consultation phases form the basis of the proposed stakeholder-based SOI system. This system will allow for continuous monitoring and rating of plant performance, facilitate optimised operation and encourage the prioritisation of performance improvement through tracking key operational metrics. Plant optimisation has become a major focus due to the transfer of all ROI water services to a national water utility from individual local authorities and the implementation of the EU Water Framework Directive.

Altered regulation of TERMINAL FLOWER 1 causes the unique vernalisation response in an arctic woodland strawberry accession.

PubMed

Koskela, Elli A; Kurokura, Takeshi; Toivainen, Tuomas; Sønsteby, Anita; Heide, Ola M; Sargent, Daniel J; Isobe, Sachiko; Jaakola, Laura; Hilmarsson, Hrannar; Elomaa, Paula; Hytönen, Timo

2017-11-01

Vernalisation requirement is an agriculturally important trait that postpones the development of cold-sensitive floral organs until the spring. The family Rosaceae includes many agriculturally important fruit and berry crops that suffer from crop losses caused by frost injury to overwintering flower buds. Recently, a vernalisation-requiring accession of the Rosaceae model woodland strawberry (Fragaria vesca) has been identified in northern Norway. Understanding the molecular basis of the vernalisation requirement in this accession would advance the development of strawberry cultivars better adapted to temperate climate. We use gene silencing, gene expression analysis, genetic mapping and population genomics to study the genetic basis of the vernalisation requirement in woodland strawberry. Our results indicate that the woodland strawberry vernalisation requirement is endemic to northern Norwegian population, and mapping data suggest the orthologue of TERMINAL FLOWER1 (FvTFL1) as the causal floral repressor. We demonstrate that exceptionally low temperatures are needed to downregulate FvTFL1 and to make these plants competent to induce flowering at low postvernalisation temperatures in the spring. We show that altered regulation of FvTFL1 in the northern Norwegian woodland strawberry accession postpones flower induction until the spring, allowing plants to avoid winter injuries of flower buds that commonly occur in temperate regions. © 2017 The Authors New Phytologist © 2017 New Phytologist Trust.

Behavioural cues of reproductive status in seahorses Hippocampus abdominalis.

PubMed

Whittington, C M; Musolf, K; Sommer, S; Wilson, A B

2013-07-01

A method is described to assess the reproductive status of male Hippocampus abdominalis on the basis of behavioural traits. The non-invasive nature of this technique minimizes handling stress and reduces sampling requirements for experimental work. It represents a useful tool to assist researchers in sample collection for studies of reproduction and development in viviparous syngnathids, which are emerging as important model species. © 2013 The Authors. Journal of Fish Biology © 2013 The Fisheries Society of the British Isles.

[Software as medical devices/medical apps : Tasks, requirements, and experiences from the point of view of a competent authority].

PubMed

Terhechte, Arno

2018-03-01

Software can be classified as a medical device according to the Medical Device Directive 93/42/EEC. The number of software products and medical apps is continuously increasing and so too is the use in health institutions (e. g., in hospitals and doctors' surgeries) for diagnosis and therapy.Different aspects of standalone software and medical apps from the perspective of the authority responsible are presented. The quality system implemented to establish a risk-based systematic inspection and supervision of manufacturers is discussed. The legal framework, as well as additional standards that are the basis for inspection, are outlined. The article highlights special aspects that occur during inspection like verification of software and interfaces, and the clinical evaluation of software. The Bezirksregierung, as the local government authority responsible in North Rhine-Westphalia, is also in charge of inspection of health institutions. Therefore this article is not limited to the manufacturers placing the software on the market, but in addition it describes the management and use of software as a medical device in hospitals.The future legal framework, the Medical Device Regulation, will strengthen the requirements and engage notified bodies more than today in the conformity assessment of software as a medical device.Manufacturers, health institutions, notified bodies and the authorities responsible are in charge of intensifying their efforts towards software as a medical device. Mutual information, improvement of skills, and inspections will lead to compliance with regulatory requirements.

[Safety monitoring of cell-based medicinal products (CBMPs)].

PubMed

Funk, Markus B; Frech, Marion; Spranger, Robert; Keller-Stanislawski, Brigitte

2015-11-01

Cell-based medicinal products (CBMPs), a category of advanced-therapy medicinal products (ATMPs), are authorised for the European market by the European Commission by means of the centralized marketing authorisation. By conforming to the German Medicinal Products Act (Sec. 4b AMG), national authorisation can be granted by the Paul-Ehrlich-Institut in Germany exclusively for ATMPs not based on a routine manufacturing procedure. In both procedures, quality, efficacy, and safety are evaluated and the risk-benefit balance is assessed. For the centralised procedure, mainly controlled clinical trial data must be submitted, whereas the requirements for national procedures could be modified corresponding to the stage of development of the ATMP. After marketing authorization, the marketing authorization/license holder is obligated to report all serious adverse reactions to the competent authority and to provide periodic safety update reports. If necessary, post-authorization safety studies could be imposed. On the basis of these regulatory measures, the safety of advanced therapies can be monitored and improved.

Generation III reactors safety requirements and the design solutions

NASA Astrophysics Data System (ADS)

Felten, P.

2009-03-01

Nuclear energy's public acceptance, and hence its development, depends on its safety. As a reactor designer, we will first briefly remind the basic safety principles of nuclear reactors' design. We will then show how the industry, and in particular Areva with its EPR, made design evolution in the wake of the Three Miles Island accident in 1979. In particular, for this new generation of reactors, severe accidents are taken into account beyond the standard design basis accidents. Today, Areva's EPR meets all so-called "generation III" safety requirements and was licensed by several nuclear safety authorities in the world. Many innovative solutions are integrated in the EPR, some of which will be introduced here.

The legal framework governing the quality of (traditional) herbal medicinal products in the European Union.

PubMed

Kroes, Burt H

2014-12-02

In the European Union a complex regulatory framework is in place for the regulation of (traditional) herbal medicinal products. It is based on the principle that a marketing authorisation granted by the competent authorities is required for placing medicinal products on the market. The requirements and procedures for acquiring such a marketing authorisation are laid down in regulations, directives and scientific guidelines. This paper gives an overview of the quality requirements for (traditional) herbal medicinal products that are contained in European pharmaceutical legislation. Pharmaceutical quality of medicinal product is the basis for ensuring safe and effective medicines. The basic principles governing the assurance of the quality of medicinal products in the European Union are primarily defined in the amended Directive 2001/83/EC and Directive 2003/63/EC. Quality requirements of herbal medicinal products are also laid down in scientific guidelines. Scientific guidelines provide a basis for practical harmonisation of how the competent authorities of EU Member States interpret and apply the detailed requirements for the demonstration of quality laid down in regulations and directives. Detailed quality requirements for herbal medicinal products on the European market are contained in European Union (EU) pharmaceutical legislation. They include a system of manufacturing authorisations which ensures that all herbal medicinal products on the European market are manufactured/imported only by authorised manufacturers, whose activities are regularly inspected by the competent authorities. Additionally, as starting materials only active substances are allowed which have been manufactured in accordance with the GMP for starting materials as adopted by the Community. The European regulatory framework encompasses specific requirements for herbal medicinal products. These requirements are independent from the legal status. Thus, the same quality standards equally apply to herbal products based on clinical evidence and traditional herbal medicinal products. The basic principle is that the quality of herbal medicinal products is intrinsically associated with the quality standard of the herbal substances and/or herbal preparations. Furthermore, the herbal substance or herbal preparation in its entirety is regarded as the active substance. Consequently, a mere determination of the content of marker(s) or constituents with known therapeutic activity is not sufficient for the quality control of herbal medicinal products. Specific quality requirements include thorough product characterisation, adherence to the Good Agricultural and Collection Practices, good manufacturing practices and validated manufacturing process, e.g., raw material testing, in-process testing, fingerprint characterisation etc. Quality control of herbal medicinal products is primarily intended to define the quality of the herbal substance/preparation and herbal medicinal product rather than to establish full characterisation. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

The European hospital exemption clause-new option for gene therapy?

PubMed

Buchholz, Christian J; Sanzenbacher, Ralf; Schüle, Silke

2012-01-01

Gene-therapy medicinal products are currently applied to patients enrolled in authorized clinical trials to demonstrate safety and efficacy. Given a positive outcome, marketing authorization can subsequently be achieved via the centralized procedure coordinated by the European Medicines Agency. With Regulation (EC) No. 1394/2007 in force, advanced therapy medicinal products, including gene- and cell-therapy products, can be excepted from the obligation of obtaining a marketing authorization via the centralized procedure under specific conditions (so-called "hospital exemption"). This hospital exemption allows the application of gene-therapy medicinal products prepared on a non-routine basis for an individual patient and used under the exclusive professional responsibility of a medical practitioner. Here, we explain the requirements to be fulfilled in order to fall under this exemption, the implementation of this regulation into the German national legislation, and its impact on gene-therapy product development in the future.

[Over- or underestimated? Bibliographic survey of the biomedical periodicals published in Hungary].

PubMed

Berhidi, Anna; Horváth, Katalin; Horváth, Gabriella; Vasas, Lívia

2013-06-30

This publication - based on an article published in 2006 - emphasises the qualities of the current biomedical periodicals of Hungarian editions. The aim of this study was to analyse how Hungarian journals meet the requirements of the scientific aspect and international visibility. Authors evaluated 93 Hungarian biomedical periodicals by 4 viewpoints of the two criteria mentioned above. 35% of the analysed journals complete the attributes of scientific aspect, 5% the international visibility, 6% fulfill all examined criteria, and 25% are indexed in international databases. 6 biomedical Hungarian periodicals covered by each of the three main bibliographic databases (Medline, Scopus, Web of Science) have the best qualities. Authors recommend to improve viewpoints of the scientific aspect and international visibility. The basis of qualitative adequacy are the accurate authors' guidelines, title, abstract, keywords of the articles in English, and the ability to publish on time.

Real-time simulation of a Doubly-Fed Induction Generator based wind power system on eMEGASimRTM Real-Time Digital Simulator

NASA Astrophysics Data System (ADS)

Boakye-Boateng, Nasir Abdulai

The growing demand for wind power integration into the generation mix prompts the need to subject these systems to stringent performance requirements. This study sought to identify the required tools and procedures needed to perform real-time simulation studies of Doubly-Fed Induction Generator (DFIG) based wind generation systems as basis for performing more practical tests of reliability and performance for both grid-connected and islanded wind generation systems. The author focused on developing a platform for wind generation studies and in addition, the author tested the performance of two DFIG models on the platform real-time simulation model; an average SimpowerSystemsRTM DFIG wind turbine, and a detailed DFIG based wind turbine using ARTEMiSRTM components. The platform model implemented here consists of a high voltage transmission system with four integrated wind farm models consisting in total of 65 DFIG based wind turbines and it was developed and tested on OPAL-RT's eMEGASimRTM Real-Time Digital Simulator.

Building deals on bedrock.

PubMed

Harding, David; Rovit, Sam

2004-09-01

The headlines are filled with the sorry tales of companies like Vivendi and AOL Time Warner that tried to use mergers and acquisitions to grow big fast or transform fundamentally weak business models. But, drawing on extensive data and experience, the authors conclude that major deals make sense in only two circumstances: when they reinforce a company's existing basis of competition or when they help a company make the shift, as the industry's competitive base changes. In most stable industries, the authors contend, only one basis--superior cost position, brand power, consumer loyalty, real-asset advantage, or government protection--leads to industry leadership, and companies should do only those deals that bolster a strategy to capitalize on that competitive base. That's what Kellogg did when it acquired Keebler. Rather than bow to price pressures from lesser players, Kellogg sought to strengthen its existing basis of competition--its brand--through Keebler's innovative distribution system. A company coping with a changing industry should embark on a series of acquisitions (most likely coupled with divestitures) aimed at moving the firm to the new competitive basis. That's what Comcast did when changes in government regulations fundamentally altered the broadcast industry. In such cases, speed is essential, the investments required are huge, and half-measures can be worse than nothing at all. Still, the research shows, successful acquirers are not those that try to swallow a single, large, supposedly transformative deal but those that go to the M&A table often and take small bites. Deals can fuel growth--as long as they're anchored in the fundamental way money is made in your industry. Fail to understand that and no amount of integration planning will keep you and your shareholders from bearing the high cost of your mistakes.

The extent of food waste generation across EU-27: different calculation methods and the reliability of their results.

PubMed

Bräutigam, Klaus-Rainer; Jörissen, Juliane; Priefer, Carmen

2014-08-01

The reduction of food waste is seen as an important societal issue with considerable ethical, ecological and economic implications. The European Commission aims at cutting down food waste to one-half by 2020. However, implementing effective prevention measures requires knowledge of the reasons and the scale of food waste generation along the food supply chain. The available data basis for Europe is very heterogeneous and doubts about its reliability are legitimate. This mini-review gives an overview of available data on food waste generation in EU-27 and discusses their reliability against the results of own model calculations. These calculations are based on a methodology developed on behalf of the Food and Agriculture Organization of the United Nations and provide data on food waste generation for each of the EU-27 member states, broken down to the individual stages of the food chain and differentiated by product groups. The analysis shows that the results differ significantly, depending on the data sources chosen and the assumptions made. Further research is much needed in order to improve the data stock, which builds the basis for the monitoring and management of food waste. © The Author(s) 2014.

Optical Method For Monitoring Tool Control For Green Burnishing With Using Of Algorithms With Adaptive Settings

NASA Astrophysics Data System (ADS)

Lukyanov, A. A.; Grigoriev, S. N.; Bobrovskij, I. N.; Melnikov, P. A.; Bobrovskij, N. M.

2017-05-01

With regard to the complexity of the new technology and increase its reliability requirements laboriousness of control operations in industrial quality control systems increases significantly. The importance of quality management control due to the fact that its promotes the correct use of production conditions, the relevant requirements are required. Digital image processing allows to reach a new technological level of production (new technological way). The most complicated automated interpretation of information is the basis for decision-making in the management of production processes. In the case of surface analysis of tools used for processing with the using of metalworking fluids (MWF) it is more complicated. The authors suggest new algorithm for optical inspection of the wear of the cylinder tool for burnishing, which used in surface plastic deformation without using of MWF. The main advantage of proposed algorithm is the possibility of automatic recognition of images of burnisher tool with the subsequent allocation of its boundaries, finding a working surface and automatically allocating the defects and wear area. Software that implements the algorithm was developed by the authors in Matlab programming environment, but can be implemented using other programming languages.

[Classifications in forensic medicine and their logical basis].

PubMed

Kovalev, A V; Shmarov, L A; Ten'kov, A A

2014-01-01

The objective of the present study was to characterize the main requirements for the correct construction of classifications used in forensic medicine, with special reference to the errors that occur in the relevant text-books, guidelines, and manuals and the ways to avoid them. This publication continues the series of thematic articles of the authors devoted to the logical errors in the expert conclusions. The preparation of further publications is underway to report the results of the in-depth analysis of the logical errors encountered in expert conclusions, text-books, guidelines, and manuals.

Monogenic Disorders of Adrenal Steroidogenesis.

PubMed

Baranowski, Elizabeth S; Arlt, Wiebke; Idkowiak, Jan

2018-06-06

Disorders of adrenal steroidogenesis comprise autosomal recessive conditions affecting steroidogenic enzymes of the adrenal cortex. Those are located within the 3 major branches of the steroidogenic machinery involved in the production of mineralocorticoids, glucocorticoids, and androgens. This mini review describes the principles of adrenal steroidogenesis, including the newly appreciated 11-oxygenated androgen pathway. This is followed by a description of pathophysiology, biochemistry, and clinical implications of steroidogenic disorders, including mutations affecting cholesterol import and steroid synthesis, the latter comprising both mutations affecting steroidogenic enzymes and co-factors required for efficient catalysis. A good understanding of adrenal steroidogenic pathways and their regulation is crucial as the basis for sound management of these disorders, which in the majority present in early childhood. © 2018 The Author(s) Published by S. Karger AG, Basel.

[3D imaging benefits in clinical pratice of orthodontics].

PubMed

Frèrejouand, Emmanuel

2016-12-01

3D imaging possibilities raised up in the last few years in the orthodontic field. In 2016, it can be used for diagnosis improvement and treatment planning by using digital set up combined to CBCT. It is relevant for orthodontic mechanic updating by creating visible or invisible customised appliances. It forms the basis of numerous scientific researches. The author explains the progress 3D imaging brings to diagnosis and clinics but also highlights the requirements it creates. The daily use of these processes in orthodontic clinical practices needs to be regulated regarding the benefit/risk ratio and the patient satisfaction. The command of the digital work flow created by these technics requires habits modifications from the orthodontist and his staff. © EDP Sciences, SFODF, 2016.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roussel, G.

Leak-Before-Break (LBB) technology has not been applied in the first design of the seven Pressurized Water Reactors the Belgian utility is currently operating. The design basis of these plants required to consider the dynamic effects associated with the ruptures to be postulated in the high energy piping. The application of the LBB technology to the existing plants has been recently approved by the Belgian Safety Authorities but with a limitation to the primary coolant loop. LBB analysis has been initiated for the Doel 3 and Tihange 2 plants to allow the withdrawal of some of the reactor coolant pump snubbersmore » at both plants and not reinstall some of the restraints after steam generator replacement at Doel 3. LBB analysis was also found beneficial to demonstrate the acceptability of the primary components and piping to the new conditions resulting from power uprating and stretch-out operation. LBB analysis has been subsequently performed on the primary coolant loop of the Tihange I plant and is currently being performed for the Doel 4 plant. Application of the LBB to the primary coolant loop is based in Belgium on the U.S. Nuclear Regulatory Commission requirements. However the Belgian Safety Authorities required some additional analyses and put some restrictions on the benefits of the LBB analysis to maintain the global safety of the plant at a sufficient level. This paper develops the main steps of the safety evaluation performed by the Belgian Safety Authorities for accepting the application of the LBB technology to existing plants and summarizes the requirements asked for in addition to the U.S. Nuclear Regulatory Commission rules.« less

Enhancement of NRC station blackout requirements for nuclear power plants

DOE Office of Scientific and Technical Information (OSTI.GOV)

McConnell, M. W.

2012-07-01

The U.S. Nuclear Regulatory Commission (NRC) established a Near-Term Task Force (NTTF) in response to Commission direction to conduct a systematic and methodical review of NRC processes and regulations to determine whether the agency should make additional improvements to its regulatory system and to make recommendations to the Commission for its policy direction, in light of the accident at the Fukushima Dai-ichi Nuclear Power Plant. The NTTF's review resulted in a set of recommendations that took a balanced approach to defense-in-depth as applied to low-likelihood, high-consequence events such as prolonged station blackout (SBO) resulting from severe natural phenomena. Part 50,more » Section 63, of Title 10 of the Code of Federal Regulations (CFR), 'Loss of All Alternating Current Power,' currently requires that each nuclear power plant must be able to cool the reactor core and maintain containment integrity for a specified duration of an SBO. The SBO duration and mitigation strategy for each nuclear power plant is site specific and is based on the robustness of the local transmission system and the transmission system operator's capability to restore offsite power to the nuclear power plant. With regard to SBO, the NTTF recommended that the NRC strengthen SBO mitigation capability at all operating and new reactors for design-basis and beyond-design-basis external events. The NTTF also recommended strengthening emergency preparedness for prolonged SBO and multi-unit events. These recommendations, taken together, are intended to clarify and strengthen US nuclear reactor safety regarding protection against and mitigation of the consequences of natural disasters and emergency preparedness during SBO. The focus of this paper is on the existing SBO requirements and NRC initiatives to strengthen SBO capability at all operating and new reactors to address prolonged SBO stemming from design-basis and beyond-design-basis external events. The NRC initiatives are intended to enhance core and spent fuel pool cooling, reactor coolant system integrity, and containment integrity. (authors)« less

AP1000{sup R} nuclear power plant safety overview for spent fuel cooling

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gorgemans, J.; Mulhollem, L.; Glavin, J.

2012-07-01

The AP1000{sup R} plant is an 1100-MWe class pressurized water reactor with passive safety features and extensive plant simplifications that enhance construction, operation, maintenance, safety and costs. The AP1000 design uses passive features to mitigate design basis accidents. The passive safety systems are designed to function without safety-grade support systems such as AC power, component cooling water, service water or HVAC. Furthermore, these passive features 'fail safe' during a non-LOCA event such that DC power and instrumentation are not required. The AP1000 also has simple, active, defense-in-depth systems to support normal plant operations. These active systems provide the first levelmore » of defense against more probable events and they provide investment protection, reduce the demands on the passive features and support the probabilistic risk assessment. The AP1000 passive safety approach allows the plant to achieve and maintain safe shutdown in case of an accident for 72 hours without operator action, meeting the expectations provided in the U.S. Utility Requirement Document and the European Utility Requirements for passive plants. Limited operator actions are required to maintain safe conditions in the spent fuel pool via passive means. In line with the AP1000 approach to safety described above, the AP1000 plant design features multiple, diverse lines of defense to ensure spent fuel cooling can be maintained for design-basis events and beyond design-basis accidents. During normal and abnormal conditions, defense-in-depth and other systems provide highly reliable spent fuel pool cooling. They rely on off-site AC power or the on-site standby diesel generators. For unlikely design basis events with an extended loss of AC power (i.e., station blackout) or loss of heat sink or both, spent fuel cooling can still be provided indefinitely: - Passive systems, requiring minimal or no operator actions, are sufficient for at least 72 hours under all possible pool heat load conditions. - After 3 days, several different means are provided to continue spent fuel cooling using installed plant equipment as well as off-site equipment with built-in connections. Even for beyond design basis accidents with postulated pool damage and multiple failures in the passive safety-related systems and in the defense-in-depth active systems, the AP1000 multiple spent fuel pool spray and fill systems provide additional lines of defense to prevent spent fuel damage. (authors)« less

The molecular genetic basis of Glanzmann thrombasthenia in the Iraqi-Jewish and Arab populations in Israel

DOE Office of Scientific and Technical Information (OSTI.GOV)

Newman, P.J.; Seligsohn, U.; Lyman, S.

1991-04-15

Glanzmann thrombasthenia is an autosomal recessive bleeding disorder characterized by a decrease or absence of functional platelet glycoprotein (GP) IIb-IIIa ({alpha}{sub IIb}{beta}{sub 3}) integrin receptors. Although thrombasthenia is a rare disorder, its occurrence is increased in some regions of the world where intracommunity marriage and consanguinity are commonplace, resulting in increased expression of autosomal recessive traits. The authors have been studying two populations having an unusually high frequency of Glanzmann disease, Iraqi Jews and Arabs living in Israel, and were able to distinguish the populations on the basis of immunodetectable GPIIIa and populations on the basis of immunodetectable GPIIIa andmore » platelet surface vitronectin receptor ({alpha}{sub v}{beta}{sub 3}) expression. In this article, they describe molecular genetic studies based on use of the PCR that have allowed us to characterize platelet mRNA sequences encoding GPIIb and GPIIIa from patients in these populations. These studies demonstrate the heterogeneity of Glanzmann thrombasthenia in different populations, and its homogeneity within geographically restricted populations, and offer insight into the requirements for integrin surface expression.« less

Nondiscrimination in Health Programs and Activities. Final rule.

PubMed

2016-05-18

This final rule implements Section 1557 of the Affordable Care Act (ACA) (Section 1557). Section 1557 prohibits discrimination on the basis of race, color, national origin, sex, age, or disability in certain health programs and activities. The final rule clarifies and codifies existing nondiscrimination requirements and sets forth new standards to implement Section 1557, particularly with respect to the prohibition of discrimination on the basis of sex in health programs other than those provided by educational institutions and the prohibition of various forms of discrimination in health programs administered by the Department of Health and Human Services (HHS or the Department) and entities established under Title I of the ACA. In addition, the Secretary is authorized to prescribe the Department's governance, conduct, and performance of its business, including, here, how HHS will apply the standards of Section 1557 to HHS-administered health programs and activities.

Molecular Genetics of the PI3K-AKT-mTOR Pathway in Genodermatoses: Diagnostic Implications and Treatment Opportunities.

PubMed

Vahidnezhad, Hassan; Youssefian, Leila; Uitto, Jouni

2016-01-01

A number of critical signaling pathways are required for homeostatic regulation of cell survival, differentiation, and proliferation during organogenesis. One of them is the PI3K-AKT-mTOR pathway consisting of a cascade of inhibitor/activator molecules. Recently, a number of heritable diseases with skin involvement, manifesting particularly with tissue overgrowth, have been shown to result from mutations in the genes in the PI3K-AKT-mTOR and interacting intracellular pathways. Many of these conditions represent an overlapping spectrum of phenotypic manifestations forming a basis for novel, unifying classifications. Identification of the mutant genes and specific mutations in these patients has implications for diagnostics and genetic counseling and provides a rational basis for the development of novel treatment modalities for this currently intractable group of disorders. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

5 CFR 304.103 - Authority.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Authority. 304.103 Section 304.103... APPOINTMENTS § 304.103 Authority. (a) Basic authority. (1) When authorized by an appropriation or other statute... expert or consultant who works on a strictly intermittent basis may be appointed under this authority...

The Fossil Calibration Database-A New Resource for Divergence Dating.

PubMed

Ksepka, Daniel T; Parham, James F; Allman, James F; Benton, Michael J; Carrano, Matthew T; Cranston, Karen A; Donoghue, Philip C J; Head, Jason J; Hermsen, Elizabeth J; Irmis, Randall B; Joyce, Walter G; Kohli, Manpreet; Lamm, Kristin D; Leehr, Dan; Patané, Josés L; Polly, P David; Phillips, Matthew J; Smith, N Adam; Smith, Nathan D; Van Tuinen, Marcel; Ware, Jessica L; Warnock, Rachel C M

2015-09-01

Fossils provide the principal basis for temporal calibrations, which are critical to the accuracy of divergence dating analyses. Translating fossil data into minimum and maximum bounds for calibrations is the most important-often least appreciated-step of divergence dating. Properly justified calibrations require the synthesis of phylogenetic, paleontological, and geological evidence and can be difficult for nonspecialists to formulate. The dynamic nature of the fossil record (e.g., new discoveries, taxonomic revisions, updates of global or local stratigraphy) requires that calibration data be updated continually lest they become obsolete. Here, we announce the Fossil Calibration Database (http://fossilcalibrations.org), a new open-access resource providing vetted fossil calibrations to the scientific community. Calibrations accessioned into this database are based on individual fossil specimens and follow best practices for phylogenetic justification and geochronological constraint. The associated Fossil Calibration Series, a calibration-themed publication series at Palaeontologia Electronica, will serve as a key pipeline for peer-reviewed calibrations to enter the database. © The Author(s) 2015. Published by Oxford University Press, on behalf of the Society of Systematic Biologists. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Color is processed less efficiently than orientation in change detection but more efficiently in visual search.

PubMed

Huang, Liqiang

2015-05-01

Basic visual features (e.g., color, orientation) are assumed to be processed in the same general way across different visual tasks. Here, a significant deviation from this assumption was predicted on the basis of the analysis of stimulus spatial structure, as characterized by the Boolean-map notion. If a task requires memorizing the orientations of a set of bars, then the map consisting of those bars can be readily used to hold the overall structure in memory and will thus be especially useful. If the task requires visual search for a target, then the map, which contains only an overall structure, will be of little use. Supporting these predictions, the present study demonstrated that in comparison to stimulus colors, bar orientations were processed more efficiently in change-detection tasks but less efficiently in visual search tasks (Cohen's d = 4.24). In addition to offering support for the role of the Boolean map in conscious access, the present work also throws doubts on the generality of processing visual features. © The Author(s) 2015.

Growing a medical practice with social media marketing.

PubMed

Laban, Jake

2012-01-01

Many medical practices are facing the lack of practice growth that their social media efforts are generating. This article provides concrete ideas that can be put in place by any medical practice to realize sustainable practice growth through social media marketing. In the article, the author demonstrates that social media marketing of the medical practice has become absolutely essential in today's evolving, competitive, and fast-paced environment. This demonstration is made through an exploration of the evolution of what "good" marketing has looked like for medical practices over time. In addition, attention is paid to the shift in the definition of good marketing that is required for the practice that is preparing a social media-marketing plan. Specifically, the article investigates the proven requirements for a balanced blend of unique and engaging promotional and nonpromotional community outreach, which is required on a daily basis to achieve the significant, lasting, and sustainable growth that the practice wishes to achieve.

Methods and principles in biomedical ethics.

PubMed

Beauchamp, T L

2003-10-01

The four principles approach to medical ethics plus specification is used in this paper. Specification is defined as a process of reducing the indeterminateness of general norms to give them increased action guiding capacity, while retaining the moral commitments in the original norm. Since questions of method are central to the symposium, the paper begins with four observations about method in moral reasoning and case analysis. Three of the four scenarios are dealt with. It is concluded in the "standard" Jehovah's Witness case that having autonomously chosen the authority of his religious institution, a Jehovah's Witness has a reasonable basis on which to refuse a recommended blood transfusion. The author's view of the child of a Jehovah's Witness scenario is that it is morally required-not merely permitted-to overrule this parental refusal of treatment. It is argued in the selling kidneys for transplantation scenario that a fair system of regulating and monitoring would be better than the present system which the author believes to be a shameful failure.

Contour interpolated radial basis functions with spline boundary correction for fast 3D reconstruction of the human articular cartilage from MR images

DOE Office of Scientific and Technical Information (OSTI.GOV)

Javaid, Zarrar; Unsworth, Charles P., E-mail: c.unsworth@auckland.ac.nz; Boocock, Mark G.

2016-03-15

Purpose: The aim of this work is to demonstrate a new image processing technique that can provide a “near real-time” 3D reconstruction of the articular cartilage of the human knee from MR images which is user friendly. This would serve as a point-of-care 3D visualization tool which would benefit a consultant radiologist in the visualization of the human articular cartilage. Methods: The authors introduce a novel fusion of an adaptation of the contour method known as “contour interpolation (CI)” with radial basis functions (RBFs) which they describe as “CI-RBFs.” The authors also present a spline boundary correction which further enhancesmore » volume estimation of the method. A subject cohort consisting of 17 right nonpathological knees (ten female and seven male) is assessed to validate the quality of the proposed method. The authors demonstrate how the CI-RBF method dramatically reduces the number of data points required for fitting an implicit surface to the entire cartilage, thus, significantly improving the speed of reconstruction over the comparable RBF reconstruction method of Carr. The authors compare the CI-RBF method volume estimation to a typical commercial package (3D DOCTOR), Carr’s RBF method, and a benchmark manual method for the reconstruction of the femoral, tibial, and patellar cartilages. Results: The authors demonstrate how the CI-RBF method significantly reduces the number of data points (p-value < 0.0001) required for fitting an implicit surface to the cartilage, by 48%, 31%, and 44% for the patellar, tibial, and femoral cartilages, respectively. Thus, significantly improving the speed of reconstruction (p-value < 0.0001) by 39%, 40%, and 44% for the patellar, tibial, and femoral cartilages over the comparable RBF model of Carr providing a near real-time reconstruction of 6.49, 8.88, and 9.43 min for the patellar, tibial, and femoral cartilages, respectively. In addition, it is demonstrated how the CI-RBF method matches the volume estimation of a typical commercial package (3D DOCTOR), Carr’s RBF method, and a benchmark manual method for the reconstruction of the femoral, tibial, and patellar cartilages. Furthermore, the performance of the segmentation method used for the extraction of the femoral, tibial, and patellar cartilages is assessed with a Dice similarity coefficient, sensitivity, and specificity measure providing high agreement to manual segmentation. Conclusions: The CI-RBF method provides a fast, accurate, and robust 3D model reconstruction that matches Carr’s RBF method, 3D DOCTOR, and a manual benchmark method in accuracy and significantly improves upon Carr’s RBF method in data requirement and computational speed. In addition, the visualization tool has been designed to quickly segment MR images requiring only four mouse clicks per MR image slice.« less

The status of state boards of health in 2010.

PubMed

Fenton, Ginger D

2011-01-01

The objective of the survey was to update information about state boards of health throughout the United States and, based on the results of the survey, to determine how the National Association of Local Boards of Health can serve as a resource to assist state boards in fulfilling their responsibilities and duties. A written survey was developed to collect information about the composition, organizational structure, statutory authority, roles, responsibilities, concerns, and needs of state boards of health. Information specific to state boards of health has not been collected on a routine basis by any organization, therefore the National Association of Local Boards of Health sought to compile current information on these boards that will be maintained and updated on a routine basis. Surveys were mailed to 31 contacts for state boards of health. After follow-up attempts, responses (n = 27) were received from all but four boards for a response rate of 87.1% with one indicating no board. Consumers and physicians were most frequently reported as required members of the boards. Board members were appointed solely by the governor in 21 (80.8%) states. Nine boards (34.6%) indicated an advisory only capacity regarding statutory authority while the others were governing, policy making, or had multiple authorities. Specific responsibilities of all of the boards included, regardless of statutory authority, advising the state chief health officer (84.6%), advising the governor (42.3%), and adopting and enforcing statutes (38.5%). State boards of health have undergone changes and likely will continue to evolve in their role in public health governance as demonstrated by this survey. This repository of current data on state boards of health could be of use to public health researchers, boards of health, and national public health organizations in strengthening public health governance.

18 CFR 1316.6 - Discrimination on the basis of age.

Code of Federal Regulations, 2013 CFR

2013-04-01

... basis of age. 1316.6 Section 1316.6 Conservation of Power and Water Resources TENNESSEE VALLEY AUTHORITY... Conditions and Certifications § 1316.6 Discrimination on the basis of age. When so indicated in TVA contract...: Discrimination On The Basis Of Age Executive Order 11141, 3 CFR, 1964-1965 Comp., p. 179, states that it is the...

18 CFR 1316.6 - Discrimination on the basis of age.

Code of Federal Regulations, 2012 CFR

2012-04-01

... basis of age. 1316.6 Section 1316.6 Conservation of Power and Water Resources TENNESSEE VALLEY AUTHORITY... Conditions and Certifications § 1316.6 Discrimination on the basis of age. When so indicated in TVA contract...: Discrimination On The Basis Of Age Executive Order 11141, 3 CFR, 1964-1965 Comp., p. 179, states that it is the...

18 CFR 1316.6 - Discrimination on the basis of age.

Code of Federal Regulations, 2010 CFR

2010-04-01

... basis of age. 1316.6 Section 1316.6 Conservation of Power and Water Resources TENNESSEE VALLEY AUTHORITY... Conditions and Certifications § 1316.6 Discrimination on the basis of age. When so indicated in TVA contract...: Discrimination On The Basis Of Age Executive Order 11141, 3 CFR, 1964-1965 Comp., p. 179, states that it is the...

18 CFR 1316.6 - Discrimination on the basis of age.

Code of Federal Regulations, 2011 CFR

2011-04-01

... basis of age. 1316.6 Section 1316.6 Conservation of Power and Water Resources TENNESSEE VALLEY AUTHORITY... Conditions and Certifications § 1316.6 Discrimination on the basis of age. When so indicated in TVA contract...: Discrimination On The Basis Of Age Executive Order 11141, 3 CFR, 1964-1965 Comp., p. 179, states that it is the...

18 CFR 1316.6 - Discrimination on the basis of age.

Code of Federal Regulations, 2014 CFR

2014-04-01

... basis of age. 1316.6 Section 1316.6 Conservation of Power and Water Resources TENNESSEE VALLEY AUTHORITY... Conditions and Certifications § 1316.6 Discrimination on the basis of age. When so indicated in TVA contract...: Discrimination On The Basis Of Age Executive Order 11141, 3 CFR, 1964-1965 Comp., p. 179, states that it is the...

High-level waste tank farm set point document

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anthony, J.A. III

1995-01-15

Setpoints for nuclear safety-related instrumentation are required for actions determined by the design authorization basis. Minimum requirements need to be established for assuring that setpoints are established and held within specified limits. This document establishes the controlling methodology for changing setpoints of all classifications. The instrumentation under consideration involve the transfer, storage, and volume reduction of radioactive liquid waste in the F- and H-Area High-Level Radioactive Waste Tank Farms. The setpoint document will encompass the PROCESS AREA listed in the Safety Analysis Report (SAR) (DPSTSA-200-10 Sup 18) which includes the diversion box HDB-8 facility. In addition to the PROCESS AREASmore » listed in the SAR, Building 299-H and the Effluent Transfer Facility (ETF) are also included in the scope.« less

[Assessment of the results of syndrome in clinical trials of dementia treated by Chinese herbal medicine].

PubMed

Ni, Jing-nian; Shi, Jing; Tian, Jin-zhou; Liu, Bing-lin; Liu, Jian-ping; Liu, Tong-hua; Xu, Shi-qian; Cui, Gong-ping; Wang, Yong-yan

2013-03-01

Chinese medical syndrome efficacy, as a second efficacy indicator, has been widely used in clinical trials of treating dementia by Chinese herbal medicine. The syndrome assessment tool is a key point in assessing the efficacy of Chinese medical syndrome. The syndrome assessment tool for dementia used nowadays needs to be optimized in content, reliability, and validity. In this paper, the authors reviewed some problems correlated with the design of Chinese medical assessment questionnaire on the basis of Chinese medical theories by combining the common requirements for questionnaire development.

Natural gas imports and exports. First quarter report 1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-08-01

The Office of Fuels Programs Prepares quarterly reports Summarizing the data provided by companies authorized to import or export natural gas. Companies are required, as a condition of their authorizations, to file quarterly reports with the OFP. This report is for the first quarter of 1994 (January--March). Attachment A shows the percentage of takes to maximum firm contract levels and the weighted average per unit price for each of the long-term importers during the five most recent reporting quarters. Attachment B shows volumes and prices of gas purchased by long-term importers and exporters during the past twelve months. Attachment Cmore » shows volume and price information for gas imported on a short-term basis. Attachment D shows the gas exported on a short-term basis to Canada and Mexico. During the first three months of 1994, data indicates that gas imports grew by about 14 percent over the level of the first quarter of 1993 (668 vs. 586 Bcf), with Canadian and Algerian imports increasing by 12 and 53 percent, respectively. During the same time period, exports declined by 15 percent (41 vs. 48 Bcf). Exports to Canada increased by 10 percent from the 1993 level (22 vs. 20 Bcf) and exports to Mexico decreased by 64 percent (5 vs. 14 Bcf).« less

Animal disease outbreak control: the use of crisis management tools.

PubMed

Kroschewski, K; Kramer, M; Micklich, A; Staubach, C; Carmanns, R; Conraths, F J

2006-04-01

In this era of globalisation the effective control of animal disease outbreaks requires powerful crisis management tools. In the 1990s software packages for different sectors of the government and agricultural industry began to be developed. In 2004, as a special application for tracking the movement of animals and animal products, the European Union developed the Trade Control and Expert System (TRACES) on the basis of its predecessor, the ANImal MOvement (ANIMO) project. The nationwide use of the ANIMO system by the veterinary authorities in Germany marked the beginning of the development in 1993 of a computerised national animal disease reporting system--the TierSeuchenNachrichten (TSN)--using the ANIMO hardware and software components. In addition to TRACES and TSN the third pillar for the management of animal disease outbreaks and crises in Germany is the national cattle and swine database--called Herkunftssicherungs- und Informationssystem für Tiere. A high degree of standardisation is necessary when integrating the different solutions at all levels of government and with the private sector. In this paper, the authors describe the use of these tools on the basis of their experience and in relation to what we can do now and what we should opt for in the future.

Delivering organisational adaptation through legislative mechanisms: Evidence from the Adaptation Reporting Power (Climate Change Act 2008).

PubMed

Jude, S R; Drew, G H; Pollard, S J T; Rocks, S A; Jenkinson, K; Lamb, R

2017-01-01

There is increasing recognition that organisations, particularly in key infrastructure sectors, are potentially vulnerable to climate change and extreme weather events, and require organisational responses to ensure they are resilient and adaptive. However, detailed evidence of how adaptation is facilitated, implemented and reported, particularly through legislative mechanisms is lacking. The United Kingdom Climate Change Act (2008), introduced the Adaptation Reporting Power, enabling the Government to direct so-called reporting authorities to report their climate change risks and adaptation plans. We describe the authors' unique role and experience supporting the Department for Environment, Food and Rural Affairs (Defra) during the Adaptation Reporting Power's first round. An evaluation framework, used to review the adaptation reports, is presented alongside evidence on how the process provides new insights into adaptation activities and triggered organisational change in 78% of reporting authorities, including the embedding of climate risk and adaptation issues. The role of legislative mechanisms and risk-based approaches in driving and delivering adaptation is discussed alongside future research needs, including the development of organisational maturity models to determine resilient and well adapting organisations. The Adaptation Reporting Power process provides a basis for similar initiatives in other countries, although a clear engagement strategy to ensure buy-in to the process and research on its long-term legacy, including the potential merits of voluntary approaches, is required. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

Analyses in Support of Risk-Informed Natural Gas Vehicle Maintenance Facility Codes and Standards: Phase II.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blaylock, Myra L.; LaFleur, Chris Bensdotter; Muna, Alice Baca

Safety standards development for maintenance facilities of liquid and compressed natural gas fueled vehicles is required to ensure proper facility design and operating procedures. Standard development organizations are utilizing risk-informed concepts to develop natural gas vehicle (NGV) codes and standards so that maintenance facilities meet acceptable risk levels. The present report summarizes Phase II work for existing NGV repair facility code requirements and highlights inconsistencies that need quantitative analysis into their effectiveness. A Hazardous and Operability study was performed to identify key scenarios of interest using risk ranking. Detailed simulations and modeling were performed to estimate the location and behaviormore » of natural gas releases based on these scenarios. Specific code conflicts were identified, and ineffective code requirements were highlighted and resolutions proposed. These include ventilation rate basis on area or volume, as well as a ceiling offset which seems ineffective at protecting against flammable gas concentrations. ACKNOWLEDGEMENTS The authors gratefully acknowledge Bill Houf (SNL -- Retired) for his assistance with the set-up and post-processing of the numerical simulations. The authors also acknowledge Doug Horne (retired) for his helpful discussions. We would also like to acknowledge the support from the Clean Cities program of DOE's Vehicle Technology Office.« less

42 CFR 440.300 - Basis.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 4 2010-10-01 2010-10-01 false Basis. 440.300 Section 440.300 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL....300 Basis. This subpart implements section 1937 of the Act, which authorizes States to provide for...

13 CFR 124.1011 - What format, degree of specificity, and basis does SBA require to consider an SDB protest?

Code of Federal Regulations, 2011 CFR

2011-01-01

..., and basis does SBA require to consider an SDB protest? 124.1011 Section 124.1011 Business Credit and... § 124.1011 What format, degree of specificity, and basis does SBA require to consider an SDB protest? (a) Format. An SDB protest need not be in any specific format in order for SBA to consider it. (b...

13 CFR 124.1011 - What format, degree of specificity, and basis does SBA require to consider an SDB protest?

Code of Federal Regulations, 2010 CFR

2010-01-01

..., and basis does SBA require to consider an SDB protest? 124.1011 Section 124.1011 Business Credit and... § 124.1011 What format, degree of specificity, and basis does SBA require to consider an SDB protest? (a) Format. An SDB protest need not be in any specific format in order for SBA to consider it. (b...

13 CFR 124.1011 - What format, degree of specificity, and basis does SBA require to consider an SDB protest?

Code of Federal Regulations, 2012 CFR

2012-01-01

..., and basis does SBA require to consider an SDB protest? 124.1011 Section 124.1011 Business Credit and... § 124.1011 What format, degree of specificity, and basis does SBA require to consider an SDB protest? (a) Format. An SDB protest need not be in any specific format in order for SBA to consider it. (b...

13 CFR 124.1011 - What format, degree of specificity, and basis does SBA require to consider an SDB protest?

Code of Federal Regulations, 2013 CFR

2013-01-01

..., and basis does SBA require to consider an SDB protest? 124.1011 Section 124.1011 Business Credit and... § 124.1011 What format, degree of specificity, and basis does SBA require to consider an SDB protest? (a) Format. An SDB protest need not be in any specific format in order for SBA to consider it. (b...

13 CFR 124.1011 - What format, degree of specificity, and basis does SBA require to consider an SDB protest?

Code of Federal Regulations, 2014 CFR

2014-01-01

..., and basis does SBA require to consider an SDB protest? 124.1011 Section 124.1011 Business Credit and... § 124.1011 What format, degree of specificity, and basis does SBA require to consider an SDB protest? (a) Format. An SDB protest need not be in any specific format in order for SBA to consider it. (b...

The Turkish Medicines and Medical Devices Agency: Comparison of Its Registration Process with Australia, Canada, Saudi Arabia, and Singapore

PubMed Central

Mashaki Ceyhan, Emel; Gürsöz, Hakki; Alkan, Ali; Coşkun, Hacer; Koyuncu, Oğuzhan; Walker, Stuart

2018-01-01

Introduction: Regulatory agency comparisons can be of more value and facilitate improvements if conducted among countries with common challenges and similar health agency characteristics. A study was conducted to compare the registration review model used by the Turkish Medicines and Medical Devices Agency (Türkiye Ilaç ve Tibbi Cihaz Kurumu; TITCK) with those of four similar-sized regulatory agencies to identify areas of strength and those requiring further improvement within the TITCK in relation to the review process as well as to assess the level of adherence to good review practices (GRevP) in order to facilitate the TITCK progress toward agency goals. Methods: A questionnaire was completed and validated by the TITCK to collect data related to agency organizational structure, regulatory review process and decision-making practices. Similar questionnaires were completed and validated by Australia's Therapeutic Goods Administration (TGA), Health Canada, Singapore's Health Science Authority (HSA), and the Saudi Arabia Food and Drug Administration (SFDA). Results: The TITCK performs a full review for all new active substance (NAS) applications. Submission of a Certificate of Pharmaceutical product (CPP) with an application is not required; however, evidence of approval in another country is required for final authorization by the TITCK. Pricing data are not required by the TITCK at the time of submission; however, pricing must be completed to enable products to be commercially available. Mean approval times at the TITCK exceeded the agency's overall target time suggesting room for improved performance, consistency, and process predictability. Measures of GRevP are in place, but the implementation by the TITCK is not currently formalized. Discussion: Comparisons made through this study enabled recommendations to the TITCK that include streamlining the good manufacturing practice (GMP) process by sharing GMP inspection outcomes and certificates issued by other authorities, thus avoiding the delays by the current process; removing the requirement for prior approval or CPP; introducing shared or joint reviews with other similar regulatory authorities; formally implementing and monitoring GRevP; defining target timing for each review milestone; redefining the pricing process; and improving transparency by developing publicly available summaries for the basis of approval. PMID:29422861

The Turkish Medicines and Medical Devices Agency: Comparison of Its Registration Process with Australia, Canada, Saudi Arabia, and Singapore.

PubMed

Mashaki Ceyhan, Emel; Gürsöz, Hakki; Alkan, Ali; Coşkun, Hacer; Koyuncu, Oğuzhan; Walker, Stuart

2018-01-01

Introduction: Regulatory agency comparisons can be of more value and facilitate improvements if conducted among countries with common challenges and similar health agency characteristics. A study was conducted to compare the registration review model used by the Turkish Medicines and Medical Devices Agency (Türkiye Ilaç ve Tibbi Cihaz Kurumu; TITCK) with those of four similar-sized regulatory agencies to identify areas of strength and those requiring further improvement within the TITCK in relation to the review process as well as to assess the level of adherence to good review practices (GRevP) in order to facilitate the TITCK progress toward agency goals. Methods: A questionnaire was completed and validated by the TITCK to collect data related to agency organizational structure, regulatory review process and decision-making practices. Similar questionnaires were completed and validated by Australia's Therapeutic Goods Administration (TGA), Health Canada, Singapore's Health Science Authority (HSA), and the Saudi Arabia Food and Drug Administration (SFDA). Results: The TITCK performs a full review for all new active substance (NAS) applications. Submission of a Certificate of Pharmaceutical product (CPP) with an application is not required; however, evidence of approval in another country is required for final authorization by the TITCK. Pricing data are not required by the TITCK at the time of submission; however, pricing must be completed to enable products to be commercially available. Mean approval times at the TITCK exceeded the agency's overall target time suggesting room for improved performance, consistency, and process predictability. Measures of GRevP are in place, but the implementation by the TITCK is not currently formalized. Discussion: Comparisons made through this study enabled recommendations to the TITCK that include streamlining the good manufacturing practice (GMP) process by sharing GMP inspection outcomes and certificates issued by other authorities, thus avoiding the delays by the current process; removing the requirement for prior approval or CPP; introducing shared or joint reviews with other similar regulatory authorities; formally implementing and monitoring GRevP; defining target timing for each review milestone; redefining the pricing process; and improving transparency by developing publicly available summaries for the basis of approval.

47 CFR 3.21 - Order of consideration.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL AUTHORIZATION AND ADMINISTRATION OF ACCOUNTING... consideration. (a) Accounting Authority applications will be processed on a first-come, first-served basis. When... postmark, will be processed first. Interim accounting authorities seeking permanent certifications through...

Authority, autonomy, responsibility and authorisation: with specific reference to adolescent mental health practice.

PubMed Central

Sutton, A

1997-01-01

Standards for professional training and practice are defined by accrediting organisations or statutory bodies. These describe the arena in which the practitioner may speak with authority. The sphere of authorised practice is further delineated by the external resources available. Within this explicit framework, unconscious mental processes can affect the professional response in potentially adverse ways. This is particularly important in mental health practice. Professionals must be prepared to examine their own responses on this basis in order to enhance their knowledge of the patient and minimise the possibilities of the patient becoming the victim of the professional's own psychopathology. The maintenance of such a position in an institution or organisation requires a similar process within its structure in order to provide the necessary setting and define the limits of good practice. In this paper, the field of adolescent mental health is specifically examined. PMID:9055159

Planning the bioterrorism response supply chain: learn and live.

PubMed

Brandeau, Margaret L; Hutton, David W; Owens, Douglas K; Bravata, Dena M

2007-01-01

Responses to bioterrorism require rapid procurement and distribution of medical and pharmaceutical supplies, trained personnel, and information. Thus, they present significant logistical challenges. On the basis of a review of the manufacturing and service supply chain literature, the authors identified five supply chain strategies that can potentially increase the speed of response to a bioterrorism attack, reduce inventories, and save money: effective supply chain network design; effective inventory management; postponement of product customization and modularization of component parts; coordination of supply chain stakeholders and appropriate use of incentives; and effective information management. The authors describe how concepts learned from published evaluations of manufacturing and service supply chains, as well as lessons learned from responses to natural disasters, naturally occurring outbreaks, and the 2001 US anthrax attacks, can be applied to design, evaluate, and improve the bioterrorism response supply chain. Such lessons could also be applied to the response supply chains for disease outbreaks and natural and manmade disasters.

Anticipatory postural adjustments for altering direction during walking.

PubMed

Xu, Dali; Carlton, Les G; Rosengren, Karl S

2004-09-01

The authors examined how individuals adapt their gait and regulate their body configuration before altering direction during walking. Eight young adults were asked to change direction during walking with different turning angles (0 degree, 45 degree, 90 degree), pivot foot (left, right), and walking speeds (normal and fast). The authors used video and force platform systems to determine participants' whole-body center of mass and the center of pressure during the step before they changed direction. The results showed that anticipatory postural adjustments occurred during the prior step and occurred earlier for the fast walking speed. Anticipatory postural adjustments were affected by all 3 variables (turn angle, pivot foot, and speed). Participants leaned backward and sideward on the prior step in anticipation of the turn. Those findings indicate that the motor system uses central control mechanisms to predict the required anticipatory adjustments and organizes the body configuration on the basis of the movement goal.

Hox2 Genes Are Required for Tonotopic Map Precision and Sound Discrimination in the Mouse Auditory Brainstem.

PubMed

Karmakar, Kajari; Narita, Yuichi; Fadok, Jonathan; Ducret, Sebastien; Loche, Alberto; Kitazawa, Taro; Genoud, Christel; Di Meglio, Thomas; Thierry, Raphael; Bacelo, Joao; Lüthi, Andreas; Rijli, Filippo M

2017-01-03

Tonotopy is a hallmark of auditory pathways and provides the basis for sound discrimination. Little is known about the involvement of transcription factors in brainstem cochlear neurons orchestrating the tonotopic precision of pre-synaptic input. We found that in the absence of Hoxa2 and Hoxb2 function in Atoh1-derived glutamatergic bushy cells of the anterior ventral cochlear nucleus, broad input topography and sound transmission were largely preserved. However, fine-scale synaptic refinement and sharpening of isofrequency bands of cochlear neuron activation upon pure tone stimulation were impaired in Hox2 mutants, resulting in defective sound-frequency discrimination in behavioral tests. These results establish a role for Hox factors in tonotopic refinement of connectivity and in ensuring the precision of sound transmission in the mammalian auditory circuit. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.

Safety considerations for outpatient electroconvulsive therapy.

PubMed

Reti, Irving M; Walker, Melinda; Pulia, Kathy; Gallegos, Jesus; Jayaram, Geetha; Vaidya, Punit

2012-03-01

As electroconvulsive therapy (ECT) requires general anesthesia and is associated with both cognitive and non-cognitive side effects, careful consideration must be given to the safety aspects of providing ECT on an outpatient basis. Drawing upon published literature and their clinical experience administering outpatient ECT, the authors propose best practices for safely providing ECT to outpatients. They review criteria for selecting patients for outpatient ECT as well as treatment and programmatic issues. The authors highlight the importance of educating referring clinicians as well as patients and their families about factors involved in the safe delivery of ECT for outpatients. Fiscal considerations and the drive toward reduced length of stay are prompting insurers and caregivers to choose outpatient over inpatient ECT. For each patient, such a choice merits a careful analysis of the risks of outpatient ECT, as well as the implementation of measures to ensure patient safety.

The agency problem and medical acting: an example of applying economic theory to medical ethics.

PubMed

Langer, Andreas; Schröder-Bäck, Peter; Brink, Alexander; Eurich, Johannes

2009-03-01

In this article, the authors attempt to build a bridge between economic theory and medical ethics to offer a new perspective to tackle ethical challenges in the physician-patient encounter. They apply elements of new institutional economics to the ethically relevant dimensions of the physician-patient relationship in a descriptive heuristic sense. The principal-agent theory can be used to analytically grasp existing action problems in the physician-patient relationship and as a basis for shaping recommendations at the institutional level. Furthermore, the patients' increased self-determination and modern opportunities for the medical laity to inform themselves lead to a less asymmetrical distribution of information between physician and patient and therefore require new interaction models. Based on the analysis presented here, the authors recommend that, apart from the physician's necessary individual ethics, greater consideration should be given to approaches of institutional ethics and hence to incentive systems within medical ethics.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ivarson, Kristine A.; Miller, Charles W.; Arola, Craig C.

Groundwater contamination by hexavalent chromium and other nuclear reactor operation-related contaminants has resulted in the need for groundwater remedial actions within the Hanford Site reactor areas (the Hanford Site 100 Area). The large geographic extent of the resultant contaminant plumes requires an extensive level of understanding of the aquifer structure, characteristics, and configuration to support assessment and design of remedial alternatives within the former 100-D, 100-H, and 100-K reactor areas. The authors have prepared two- and three-dimensional depictions of the key subsurface geologic structures at two Hanford Site reactor operable units (100-K and 100-D/H). These depictions, prepared using commercial-off-the-shelf (COTS)more » visualization software, provide a basis for expanding the understanding of groundwater contaminant migration pathways, including identification of geologically-defined preferential groundwater flow pathways. These identified preferential flow pathways support the conceptual site model and help explain both historical and current contaminant distribution and transport. (authors)« less

Gender verification: a term whose time has come and gone.

PubMed

Hercher, Laura

2010-12-01

The process of testing to determine gender in putatively female athletes was developed in order to prevent cheating, but has devolved instead into a clumsy mechanism for detecting disorders of sexual development (DSD's). In over thirty years of compulsory testing, individuals with DSD's have been stigmatized and some have been denied the right to compete, although frequently their condition provided no competitive advantage. More recent guidelines require testing only on a case-by-case basis; the South African runner Caster Semenya was the first major test of this policy, and her experience points to the need for a more sensitive and confidential process. In addition, her case dramatizes the inadequacy of the term "gender verification." Gender identity is a complex entity and resists simple classification. Sports authorities may set guidelines for who can compete, but they should refrain from taking on themselves the authority to decide who is and who is not a female.

Research on a dynamic workflow access control model

NASA Astrophysics Data System (ADS)

Liu, Yiliang; Deng, Jinxia

2007-12-01

In recent years, the access control technology has been researched widely in workflow system, two typical technologies of that are RBAC (Role-Based Access Control) and TBAC (Task-Based Access Control) model, which has been successfully used in the role authorizing and assigning in a certain extent. However, during the process of complicating a system's structure, these two types of technology can not be used in minimizing privileges and separating duties, and they are inapplicable when users have a request of frequently changing on the workflow's process. In order to avoid having these weakness during the applying, a variable flow dynamic role_task_view (briefly as DRTVBAC) of fine-grained access control model is constructed on the basis existed model. During the process of this model applying, an algorithm is constructed to solve users' requirements of application and security needs on fine-grained principle of privileges minimum and principle of dynamic separation of duties. The DRTVBAC model is implemented in the actual system, the figure shows that the task associated with the dynamic management of role and the role assignment is more flexible on authority and recovery, it can be met the principle of least privilege on the role implement of a specific task permission activated; separated the authority from the process of the duties completing in the workflow; prevented sensitive information discovering from concise and dynamic view interface; satisfied with the requirement of the variable task-flow frequently.

Imaging fluorescence detected linear dichroism of plant cell walls in laser scanning confocal microscope.

PubMed

Steinbach, Gábor; Pomozi, István; Zsiros, Ottó; Páy, Anikó; Horváth, Gábor V; Garab, Gyozo

2008-03-01

Anisotropy carries important information on the molecular organization of biological samples. Its determination requires a combination of microscopy and polarization spectroscopy tools. The authors constructed differential polarization (DP) attachments to a laser scanning microscope in order to determine physical quantities related to the anisotropic distribution of molecules in microscopic samples; here the authors focus on fluorescence-detected linear dichroism (FDLD). By modulating the linear polarization of the laser beam between two orthogonally polarized states and by using a demodulation circuit, the authors determine the associated transmitted and fluorescence intensity-difference signals, which serve the basis for LD (linear dichroism) and FDLD, respectively. The authors demonstrate on sections of Convallaria majalis root tissue stained with Acridin Orange that while (nonconfocal) LD images remain smeared and weak, FDLD images recorded in confocal mode reveal strong anisotropy of the cell wall. FDLD imaging is suitable for mapping the anisotropic distribution of transition dipoles in 3 dimensions. A mathematical model is proposed to account for the fiber-laminate ultrastructure of the cell wall and for the intercalation of the dye molecules in complex, highly anisotropic architecture. Copyright 2007 International Society for Analytical Cytology.

Case reports: Publication standards in forensic psychiatry.

PubMed

Hanson, Annette; Martinez, Richard; Candilis, Philip J

2014-01-01

Psychiatrists who publish case reports are required to seek informed consent from their subjects on the basis of the ethics-related obligation to maintain patient confidentiality. Academic journals have developed editorial standards to fulfill this obligation. Forensic evaluations do not create a doctor-patient relationship in the traditional sense, and information obtained through a forensic evaluation may also be found in the public domain. This public exposure is particularly likely, given the development of open access publishing standards, online journals, and increasing professional involvement in social media. This article outlines the ethics of informed consent in published case reports for general and forensic psychiatry and offers recommendations for forensic case study publishing. The authors suggest changes in the current requirements stated in The Journal for publication of case reports. © 2014 American Academy of Psychiatry and the Law.

42 CFR 1003.102 - Basis for civil money penalties and assessments.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 5 2012-10-01 2012-10-01 false Basis for civil money penalties and assessments... AND HUMAN SERVICES OIG AUTHORITIES CIVIL MONEY PENALTIES, ASSESSMENTS AND EXCLUSIONS § 1003.102 Basis for civil money penalties and assessments. (a) The OIG may impose a penalty and assessment against any...

42 CFR 1003.102 - Basis for civil money penalties and assessments.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 5 2014-10-01 2014-10-01 false Basis for civil money penalties and assessments... AND HUMAN SERVICES OIG AUTHORITIES CIVIL MONEY PENALTIES, ASSESSMENTS AND EXCLUSIONS § 1003.102 Basis for civil money penalties and assessments. (a) The OIG may impose a penalty and assessment against any...

42 CFR 1003.102 - Basis for civil money penalties and assessments.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 5 2011-10-01 2011-10-01 false Basis for civil money penalties and assessments... AND HUMAN SERVICES OIG AUTHORITIES CIVIL MONEY PENALTIES, ASSESSMENTS AND EXCLUSIONS § 1003.102 Basis for civil money penalties and assessments. (a) The OIG may impose a penalty and assessment against any...

42 CFR 1003.102 - Basis for civil money penalties and assessments.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 5 2013-10-01 2013-10-01 false Basis for civil money penalties and assessments... AND HUMAN SERVICES OIG AUTHORITIES CIVIL MONEY PENALTIES, ASSESSMENTS AND EXCLUSIONS § 1003.102 Basis for civil money penalties and assessments. (a) The OIG may impose a penalty and assessment against any...

Specifics of Information Basis of Educational Activity of a Bachelor Student

ERIC Educational Resources Information Center

Slepko, Yury N.; Baranova, Natalia A.; Fayurshina, Elena A.; Mitiukov, Nicholas W.

2016-01-01

The discussion of the results of an empirical research of the problem of forming the information basis of educational activity of students studying in pedagogical higher education institution is carried out in the article. The information basis of educational activity is considered by the authors as a subsystem of psychological system of…

40 CFR 7.60 - Prohibitions and requirements relating to employment.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Discrimination Prohibited on the Basis of Handicap § 7.60 Prohibitions and requirements relating to employment. (a) No qualified handicapped person shall, on the basis of handicap, be subjected to discrimination... manner which ensures that discrimination on the basis of handicap does not occur, and shall not limit...

40 CFR 7.60 - Prohibitions and requirements relating to employment.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Discrimination Prohibited on the Basis of Handicap § 7.60 Prohibitions and requirements relating to employment. (a) No qualified handicapped person shall, on the basis of handicap, be subjected to discrimination... manner which ensures that discrimination on the basis of handicap does not occur, and shall not limit...

40 CFR 7.60 - Prohibitions and requirements relating to employment.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Discrimination Prohibited on the Basis of Handicap § 7.60 Prohibitions and requirements relating to employment. (a) No qualified handicapped person shall, on the basis of handicap, be subjected to discrimination... manner which ensures that discrimination on the basis of handicap does not occur, and shall not limit...

40 CFR 7.60 - Prohibitions and requirements relating to employment.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Discrimination Prohibited on the Basis of Handicap § 7.60 Prohibitions and requirements relating to employment. (a) No qualified handicapped person shall, on the basis of handicap, be subjected to discrimination... manner which ensures that discrimination on the basis of handicap does not occur, and shall not limit...

48 CFR 406.302-70 - Otherwise authorized by law.

Code of Federal Regulations, 2010 CFR

2010-10-01

... law. 406.302-70 Section 406.302-70 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE... Otherwise authorized by law. (a) Authority. Section 1472 of the National Agricultural Research, Extension.... Therefore: (1) Contracts under the authority of the Act shall be awarded on a competitive basis to the...

48 CFR 406.302-70 - Otherwise authorized by law.

Code of Federal Regulations, 2011 CFR

2011-10-01

... law. 406.302-70 Section 406.302-70 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE... Otherwise authorized by law. (a) Authority. Section 1472 of the National Agricultural Research, Extension.... Therefore: (1) Contracts under the authority of the Act shall be awarded on a competitive basis to the...

Two experimental tests of relational models of procedural justice: non-instrumental voice and authority group membership.

PubMed

Platow, Michael J; Eggins, Rachael A; Chattopadhyay, Rachana; Brewer, Greg; Hardwick, Lisa; Milsom, Laurin; Brocklebank, Jacinta; Lalor, Thérèse; Martin, Rowena; Quee, Michelle; Vassallo, Sara; Welsh, Jenny

2013-06-01

In both a laboratory experiment (in Australia) using university as the basis of group membership, and a scenario experiment (in India) using religion as the basis of group membership, we observe more favourable respect and fairness ratings in response to an in-group authority than an out-group authority who administers non-instrumental voice. Moreover, we observe in our second experiment that reported likelihood of protest (herein called "social-change voice") was relatively high following non-instrumental voice from an out-group authority, but relatively low following non-instrumental voice from an in-group authority. Our findings are consistent with relational models of procedural justice, and extend the work by examining likely use of alternative forms of voice as well as highlighting the relative importance of instrumentality. ©2012 The British Psychological Society.

Evidence-Based Nonpharmacological Practices to Address Behavioral and Psychological Symptoms of Dementia.

PubMed

Scales, Kezia; Zimmerman, Sheryl; Miller, Stephanie J

2018-01-18

To draw from systematic and other literature reviews to identify, describe, and critique nonpharmacological practices to address behavioral and psychological symptoms of dementia (BPSDs) and provide evidence-based recommendations for dementia care especially useful for potential adopters. A search of systematic and other literature reviews published from January 2010 through January 2017. Nonpharmacological practices were summarized to describe the overall conceptual basis related to effectiveness, the practice itself, and the size and main conclusions of the evidence base. Each practice was also critically reviewed to determine acceptability, harmful effects, elements of effectiveness, and level of investment required, based on time needed for training/implementation, specialized care provider requirements, and equipment/capital requirements. Nonpharmacological practices to address BPSDs include sensory practices (aromatherapy, massage, multi-sensory stimulation, bright light therapy), psychosocial practices (validation therapy, reminiscence therapy, music therapy, pet therapy, meaningful activities), and structured care protocols (bathing, mouth care). Most practices are acceptable, have no harmful effects, and require minimal to moderate investment. Nonpharmacological practices are person-centered, and their selection can be informed by considering the cause and meaning of the individual's behavioral and psychological symptoms. Family caregivers and paid care providers can implement evidence-based practices in home or residential care settings, although some practices require the development of more specific protocols if they are to become widely used in an efficacious manner. © The Author(s) 2018. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Comparison of two drug safety signals in a pharmacovigilance data mining framework.

PubMed

Tubert-Bitter, Pascale; Bégaud, Bernard; Ahmed, Ismaïl

2016-04-01

Since adverse drug reactions are a major public health concern, early detection of drug safety signals has become a top priority for regulatory agencies and the pharmaceutical industry. Quantitative methods for analyzing spontaneous reporting material recorded in pharmacovigilance databases through data mining have been proposed in the last decades and are increasingly used to flag potential safety problems. While automated data mining is motivated by the usually huge size of pharmacovigilance databases, it does not systematically produce relevant alerts. Moreover, each detected signal requires appropriate assessment that may involve investigation of the whole therapeutic class. The goal of this article is to provide a methodology for comparing two detected signals. It is nested within the automated surveillance framework as (1) no extra information is required and (2) no simple inference on the actual risks can be extrapolated from spontaneous reporting data. We designed our methodology on the basis of two classical methods used for automated signal detection: the Bayesian Gamma Poisson Shrinker and the frequentist Proportional Reporting Ratio. A simulation study was conducted to assess the performances of both proposed methods. The latter were used to compare cardiovascular signals for two HIV treatments from the French pharmacovigilance database. © The Author(s) 2012.

Disruptive innovation in academic medical centers: balancing accountable and academic care.

PubMed

Stein, Daniel; Chen, Christopher; Ackerly, D Clay

2015-05-01

Numerous academic medicine leaders have argued that academic referral centers must prepare for the growing importance of accountability-driven payment models by adopting population health initiatives. Although this shift has merit, execution of this strategy will prove significantly more problematic than most observers have appreciated. The authors describe how successful implementation of an accountable care health strategy within a referral academic medical center (AMC) requires navigating a critical tension: The academic referral business model, driven by tertiary-level care, is fundamentally in conflict with population health. Referral AMCs that create successful value-driven population health systems within their organizations will in effect disrupt their own existing tertiary care businesses. The theory of disruptive innovation suggests that balancing the push and pull of academic and accountable care within a single organization is achievable. However, it will require significant shifts in resource allocation and changes in management structure to enable AMCs to make the inherent difficult choices and trade-offs that will ensue. On the basis of the theories of disruptive innovation, the authors present recommendations for how academic health systems can successfully navigate these issues as they transition toward accountability-driven care.

Opportunities of energy supply of farm holdings on the basis of small-scale renewable energy sources

NASA Astrophysics Data System (ADS)

Efendiev, A. M.; Nikolaev, Yu. E.; Evstaf'ev, D. P.

2016-02-01

One of the major national economic problems of Russia is raising of agricultural production, which will provide strategic security and sustainable supply of the population with provisions. Creation of subsidiary small holdings, farm holdings, and peasant farm holdings will require addressing issues of energy supply. At considerable distance of small farms from centralized energy systems (by fuel, electricity and thermal energy) it is proposed to create a system of local energy networks on the basis of low-powered power plants using renewable energy sources (RES). There is economic unreasonableness of use of imported components of small power plants. Creation of new combined small power plants on renewable energy sources produced by domestic manufacturers is recommended. Schemes of arrangements of small power plants based on renewable energy sources are proposed, variants and characteristics of a basic source are provided—biogas plants developed by the authors. Calculations revealed that heat and power supply of self-contained farms distant from small power plants based on renewable energy sources is 2.5-2.6 times cheaper than from centralized networks. Production of biogas through anaerobic fermentation of organic waste of cattle complexes is considered as the basis. The analysis of biowaste output in various cattle farms is carried out, and the volume of biogas is determined to meet the requirements of these farms in electrical and thermal energy. The objective of the present article is to study the possibility of creating small combined power plants in Russia based on renewable sources of energy for independent consumers.

Intelligent Support System of Steel Technical Preparation in an Arc Furnace: Functional Scheme of Interactive Builder of the Multi Objective Optimization Problem

NASA Astrophysics Data System (ADS)

Logunova, O. S.; Sibileva, N. S.

2017-12-01

The purpose of the study is to increase the efficiency of the steelmaking process in large capacity arc furnace on the basis of implementation a new decision-making system about the composition of charge materials. The authors proposed an interactive builder for the formation of the optimization problem, taking into account the requirements of the customer, normative documents and stocks of charge materials in the warehouse. To implement the interactive builder, the sets of deterministic and stochastic model components are developed, as well as a list of preferences of criteria and constraints.

[The Innovation Office of the Paul-Ehrlich-Institut. Regulatory support during the scientific development of ATMP].

PubMed

Ziegele, B; Dahl, L; Müller, A T

2011-07-01

In conformity with Regulation (EC) No. 1394/2007, advanced therapy medicinal products (ATMP) are now subject to the centralized marketing authorization procedure. This also applies to most medicinal products in regenerative medicine. ATMP that have been marketed in a member state by the end of 2008 must be centrally authorized by the end of 2012 at the latest. In exceptional cases, a national authorization is acceptable. Developers of these medicinal products are usually academic institutions or small- and medium-sized enterprises (SME). They focus on scientific aspects and usually have little experience with pharmaceutical law. The Innovation Office of the Paul-Ehrlich-Institut (PEI) is designed to support developers of medicinal products in the areas between research and development, on the one hand, and regulatory requirements, on the other. Its main role is supportive advice in the regulatory field with an emphasis on ATMP. For this purpose, the Innovation Office makes use of core competences from various experts at the PEI in order to provide a quality consulting service to those companies who are seeking advice as early as possible and hand in hand with the development process. The aim is to support the developer to identify the appropriate regulatory pathway and to provide advice for each individual medicinal product at its corresponding stage of development in order to develop a high-quality ATMP manufactured on the basis of positive nonclinical results and appropriate clinical studies that meet all the necessary requirements for the application of a marketing authorization.

Denial and Affirmation in Victorian Thought

ERIC Educational Resources Information Center

Euwema, Ben

1969-01-01

Discussion of the Victorian outlook on life with emphasis on the works of Browning, Tennyson and George Eliot. The author suggests that these authors attempted to "reconstruct christianity and to find a "firm basis for social progress and personal fulfillment. (Author/AP)

Safety equipment list for the 241-SY-101 RAPID mitigation project

DOE Office of Scientific and Technical Information (OSTI.GOV)

MORRIS, K.L.

1999-06-29

This document provides the safety classification for the safety (safety class and safety RAPID Mitigation Project. This document is being issued as the project SEL until the supporting authorization basis documentation, this document will be superseded by the TWRS SEL (LMHC 1999), documentation istlralized. Upon implementation of the authorization basis significant) structures, systems, and components (SSCS) associated with the 241-SY-1O1 which will be updated to include the information contained herein.

[Logopedia and pediatric psychiatry].

PubMed

Dvorák, J

1990-12-01

The author presents some methods of special logopaedic examinations of children hospitalized in a psychiatric sanatorium for children. This diagnosis is part of a multidimensional evaluation of the child and the basis for the special development of verbal performance. The author mentions therapeutic methods some diagnostic groups and emphasizes that this work is irreplaceable in the comprehensive concept of paedopsychiatric treatment. Effective logopaedic assistance depends on professional skill which is not taught to teachers at present. In the conclusion the author submits the demand that specialists in this field should be according to norms on the staff of these institutions and should not be engaged only on an optional basis.

36 CFR 223.195 - Procedures for identifying and marking unprocessed timber.

Code of Federal Regulations, 2010 CFR

2010-07-01

... procedures required herein. (f) Waiver of branding requirements. Regional Foresters may waive the branding... individual timber sale basis, all or a portion of the branding requirements pursuant to paragraph (c)(2) of...) Regions 5 and 6. On an individual timber sale basis, the branding requirement pursuant to paragraph (c)(2...

36 CFR 223.195 - Procedures for identifying and marking unprocessed timber.

Code of Federal Regulations, 2011 CFR

2011-07-01

... procedures required herein. (f) Waiver of branding requirements. Regional Foresters may waive the branding... individual timber sale basis, all or a portion of the branding requirements pursuant to paragraph (c)(2) of...) Regions 5 and 6. On an individual timber sale basis, the branding requirement pursuant to paragraph (c)(2...

Neuronal and non-neuronal signals regulate Caernorhabditis elegans avoidance of contaminated food.

PubMed

Anderson, Alexandra; McMullan, Rachel

2018-07-19

One way in which animals minimize the risk of infection is to reduce their contact with contaminated food. Here, we establish a model of pathogen-contaminated food avoidance using the nematode worm Caernorhabditis elegans We find that avoidance of pathogen-contaminated food protects C. elegans from the deleterious effects of infection and, using genetic approaches, demonstrate that multiple sensory neurons are required for this avoidance behaviour. In addition, our results reveal that the avoidance of contaminated food requires bacterial adherence to non-neuronal cells in the tail of C. elegans that are also required for the cellular immune response. Previous studies in C. elegans have contributed significantly to our understanding of molecular and cellular basis of host-pathogen interactions and our model provides a unique opportunity to gain basic insights into how animals avoid contaminated food.This article is part of the Theo Murphy meeting issue 'Evolution of pathogen and parasite avoidance behaviours'. © 2018 The Authors.

[The possibilities of innovation of extemporaneous preparation in pharmacies in the Czech Republic].

PubMed

Sklenář, Zbyněk; Horáčková, Kateřina

2012-02-01

Extemporaneously prepared products still have an irreplaceable role in therapy. In order to boost the magistral preparation, the availability of appropriate substances for the pharmacies must be ensured. This is due to the fact that many commercial pharmaceutical products containing these active ingredients do not comply with the individual requirements of a particular patient. Based on the practice requirements, the most requested substances have been chosen and within two years 16 pure substances with quality certificates have been provided for magistral preparation in pharmacies, and there are other chemicals coming. The increased availability of these chemicals should in particular eliminate the inappropriate and sometimes unlawful use of commercial medicinal products in extemporaneously prepared products. The paper presents 16 substances and formulations created by the authors, some of which are based on foreign formulations; however, they have been adapted to meet the requirements of the domestic environment. These products should create the basis of standardized formulations for preparation in pharmacies in the Czech Republic.

Transcriptome analysis of the planarian eye identifies ovo as a specific regulator of eye regeneration.

PubMed

Lapan, Sylvain W; Reddien, Peter W

2012-08-30

Among the millions of invertebrate species with visual systems, the genetic basis of eye development and function is well understood only in Drosophila melanogaster. We describe an eye transcriptome for the planarian Schmidtea mediterranea. Planarian photoreceptors expressed orthologs of genes required for phototransduction and microvillus structure in Drosophila and vertebrates, and optic pigment cells expressed solute transporters and melanin synthesis enzymes similar to those active in the vertebrate retinal pigment epithelium. Orthologs of several planarian eye genes, such as bestrophin-1 and Usher syndrome genes, cause eye defects in mammals when perturbed and were not previously described to have roles in invertebrate eyes. Five previously undescribed planarian eye transcription factors were required for normal eye formation during head regeneration. In particular, a conserved, transcription-factor-encoding ovo gene was expressed from the earliest stages of eye regeneration and was required for regeneration of all cell types of the eye. Copyright © 2012 The Authors. Published by Elsevier Inc. All rights reserved.

26 CFR 54.9801-1 - Basis and scope.

Code of Federal Regulations, 2010 CFR

2010-04-01

... enrollment periods. (5) Prohibition against discrimination on the basis of health factors. (6) Additional requirements prohibiting discrimination based on genetic information. (c) Similar requirements under the...

26 CFR 54.9801-1 - Basis and scope.

Code of Federal Regulations, 2011 CFR

2011-04-01

... enrollment periods. (5) Prohibition against discrimination on the basis of health factors. (6) Additional requirements prohibiting discrimination based on genetic information. (c) Similar requirements under the...

45 CFR 160.402 - Basis for a civil money penalty.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 1 2012-10-01 2012-10-01 false Basis for a civil money penalty. 160.402 Section... RELATED REQUIREMENTS GENERAL ADMINISTRATIVE REQUIREMENTS Imposition of Civil Money Penalties § 160.402 Basis for a civil money penalty. (a) General rule. Subject to § 160.410, the Secretary will impose a...

45 CFR 160.402 - Basis for a civil money penalty.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 1 2013-10-01 2013-10-01 false Basis for a civil money penalty. 160.402 Section... RELATED REQUIREMENTS GENERAL ADMINISTRATIVE REQUIREMENTS Imposition of Civil Money Penalties § 160.402 Basis for a civil money penalty. (a) General rule. Subject to § 160.410, the Secretary will impose a...

45 CFR 160.402 - Basis for a civil money penalty.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 1 2014-10-01 2014-10-01 false Basis for a civil money penalty. 160.402 Section... RELATED REQUIREMENTS GENERAL ADMINISTRATIVE REQUIREMENTS Imposition of Civil Money Penalties § 160.402 Basis for a civil money penalty. (a) General rule. Subject to § 160.410, the Secretary will impose a...

45 CFR 160.402 - Basis for a civil money penalty.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 1 2011-10-01 2011-10-01 false Basis for a civil money penalty. 160.402 Section... RELATED REQUIREMENTS GENERAL ADMINISTRATIVE REQUIREMENTS Imposition of Civil Money Penalties § 160.402 Basis for a civil money penalty. (a) General rule. Subject to § 160.410, the Secretary will impose a...

45 CFR 160.402 - Basis for a civil money penalty.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Basis for a civil money penalty. 160.402 Section... RELATED REQUIREMENTS GENERAL ADMINISTRATIVE REQUIREMENTS Imposition of Civil Money Penalties § 160.402 Basis for a civil money penalty. (a) General rule. Subject to § 160.410, the Secretary will impose a...

18 CFR 1300.106 - Harassment on the basis of race, color, religion, age, or disability.

Code of Federal Regulations, 2010 CFR

2010-04-01

... of race, color, religion, age, or disability. 1300.106 Section 1300.106 Conservation of Power and... AUTHORITY § 1300.106 Harassment on the basis of race, color, religion, age, or disability. It is TVA policy... basis of race, color, religion, age, or disability. Accordingly, all employees must avoid any action or...

18 CFR 1300.106 - Harassment on the basis of race, color, religion, age, or disability.

Code of Federal Regulations, 2011 CFR

2011-04-01

... of race, color, religion, age, or disability. 1300.106 Section 1300.106 Conservation of Power and... AUTHORITY § 1300.106 Harassment on the basis of race, color, religion, age, or disability. It is TVA policy... basis of race, color, religion, age, or disability. Accordingly, all employees must avoid any action or...

18 CFR 1300.106 - Harassment on the basis of race, color, religion, age, or disability.

Code of Federal Regulations, 2013 CFR

2013-04-01

... of race, color, religion, age, or disability. 1300.106 Section 1300.106 Conservation of Power and... AUTHORITY § 1300.106 Harassment on the basis of race, color, religion, age, or disability. It is TVA policy... basis of race, color, religion, age, or disability. Accordingly, all employees must avoid any action or...

18 CFR 1300.106 - Harassment on the basis of race, color, religion, age, or disability.

Code of Federal Regulations, 2014 CFR

2014-04-01

... of race, color, religion, age, or disability. 1300.106 Section 1300.106 Conservation of Power and... AUTHORITY § 1300.106 Harassment on the basis of race, color, religion, age, or disability. It is TVA policy... basis of race, color, religion, age, or disability. Accordingly, all employees must avoid any action or...

18 CFR 1300.106 - Harassment on the basis of race, color, religion, age, or disability.

Code of Federal Regulations, 2012 CFR

2012-04-01

... of race, color, religion, age, or disability. 1300.106 Section 1300.106 Conservation of Power and... AUTHORITY § 1300.106 Harassment on the basis of race, color, religion, age, or disability. It is TVA policy... basis of race, color, religion, age, or disability. Accordingly, all employees must avoid any action or...

38 CFR 36.4225 - Authority to close manufactured home loans on the automatic basis.

Code of Federal Regulations, 2014 CFR

2014-07-01

... on a normal accounting or business cycle. The lender's latest financial statements (profit and loss... manufactured home loans on the automatic basis. 36.4225 Section 36.4225 Pensions, Bonuses, and Veterans' Relief... manufactured home loans on the automatic basis. (a) Supervised lenders of the classes described in 38 U.S.C...

38 CFR 36.4225 - Authority to close manufactured home loans on the automatic basis.

Code of Federal Regulations, 2011 CFR

2011-07-01

... on a normal accounting or business cycle. The lender's latest financial statements (profit and loss... manufactured home loans on the automatic basis. 36.4225 Section 36.4225 Pensions, Bonuses, and Veterans' Relief... manufactured home loans on the automatic basis. (a) Supervised lenders of the classes described in 38 U.S.C...

38 CFR 36.4225 - Authority to close manufactured home loans on the automatic basis.

Code of Federal Regulations, 2013 CFR

2013-07-01

... on a normal accounting or business cycle. The lender's latest financial statements (profit and loss... manufactured home loans on the automatic basis. 36.4225 Section 36.4225 Pensions, Bonuses, and Veterans' Relief... manufactured home loans on the automatic basis. (a) Supervised lenders of the classes described in 38 U.S.C...

38 CFR 36.4225 - Authority to close manufactured home loans on the automatic basis.

Code of Federal Regulations, 2012 CFR

2012-07-01

... on a normal accounting or business cycle. The lender's latest financial statements (profit and loss... manufactured home loans on the automatic basis. 36.4225 Section 36.4225 Pensions, Bonuses, and Veterans' Relief... manufactured home loans on the automatic basis. (a) Supervised lenders of the classes described in 38 U.S.C...

Genomics of coloration in natural animal populations.

PubMed

San-Jose, Luis M; Roulin, Alexandre

2017-07-05

Animal coloration has traditionally been the target of genetic and evolutionary studies. However, until very recently, the study of the genetic basis of animal coloration has been mainly restricted to model species, whereas research on non-model species has been either neglected or mainly based on candidate approaches, and thereby limited by the knowledge obtained in model species. Recent high-throughput sequencing technologies allow us to overcome previous limitations, and open new avenues to study the genetic basis of animal coloration in a broader number of species and colour traits, and to address the general relevance of different genetic structures and their implications for the evolution of colour. In this review, we highlight aspects where genome-wide studies could be of major utility to fill in the gaps in our understanding of the biology and evolution of animal coloration. The new genomic approaches have been promptly adopted to study animal coloration although substantial work is still needed to consider a larger range of species and colour traits, such as those exhibiting continuous variation or based on reflective structures. We argue that a robust advancement in the study of animal coloration will also require large efforts to validate the functional role of the genes and variants discovered using genome-wide tools.This article is part of the themed issue 'Animal coloration: production, perception, function and application'. © 2017 The Author(s).

Watermarking-based protection of remote sensing images: requirements and possible solutions

NASA Astrophysics Data System (ADS)

Barni, Mauro; Bartolini, Franco; Cappellini, Vito; Magli, Enrico; Olmo, Gabriella

2001-12-01

Earth observation missions have recently attracted ag rowing interest form the scientific and industrial communities, mainly due to the large number of possible applications capable to exploit remotely sensed data and images. Along with the increase of market potential, the need arises for the protection of the image products from non-authorized use. Such a need is a very crucial one even because the Internet and other public/private networks have become preferred means of data exchange. A crucial issue arising when dealing with digital image distribution is copyright protection. Such a problem has been largely addressed by resorting to watermarking technology. A question that obviously arises is whether the requirements imposed by remote sensing imagery are compatible with existing watermarking techniques. On the basis of these motivations, the contribution of this work is twofold: i) assessment of the requirements imposed by the characteristics of remotely sensed images on watermark-based copyright protection ii) analysis of the state-of-the-art, and performance evaluation of existing algorithms in terms of the requirements at the previous point.

47 CFR 73.99 - Presunrise service authorization (PSRA) and postsunset service authorization (PSSA).

Code of Federal Regulations, 2010 CFR

2010-10-01

... purposes. (b) Presunrise service authorizations (PSRA) permit: (1) Class D stations operating on Mexican... (PSSA) permit: (1) Class D stations located on Mexican, Bahamian, and Canadian priority Class A clear... basis and does not confer license rights. No request for such authority need be filed. However, stations...

47 CFR 1.901 - Basis and purpose.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Wireless Radio Services Applications and Proceedings Scope and Authority § 1.901 Basis and purpose. These... licensed in the Wireless Radio Services as described in this part and in parts 13, 20, 22, 24, 26, 27, 74...

47 CFR 1.901 - Basis and purpose.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Wireless Radio Services Applications and Proceedings Scope and Authority § 1.901 Basis and purpose. These... licensed in the Wireless Radio Services as described in this part and in parts 13, 20, 22, 24, 26, 27, 74...

47 CFR 1.901 - Basis and purpose.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Wireless Radio Services Applications and Proceedings Scope and Authority § 1.901 Basis and purpose. These... licensed in the Wireless Radio Services as described in this part and in parts 13, 20, 22, 24, 26, 27, 74...

Forecasting risk of bankruptcy for machine-building plants

NASA Astrophysics Data System (ADS)

Telipenko, E.; Zakharova, A.; Sopova, Svetlana

2015-09-01

The paper presents an overview of well-known bankruptcy risk forecasting models, elaborated as by Russian so by foreign authors, on the basis of the data about financial and business activities of the biggest machine-building Russian plants. The authors substantiate and confirm appropriateness of a fuzzy set model to the problem of bankruptcy risk forecasting. This model is worked out on the basis of 10 most important factors, which have the greatest influence on sales proceeds as the main financial source for a production plant.

40 CFR 98.86 - Data reporting requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Data reporting requirements. 98.86... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Cement Production § 98.86 Data reporting requirements. In..., dry basis). (13) Annual consumption of each raw material (dry basis). (14) Number of times missing...

45 CFR 144.200 - Basis.

Code of Federal Regulations, 2011 CFR

2011-10-01

... DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS REQUIREMENTS RELATING TO HEALTH INSURANCE COVERAGE Source: § 144.200 Basis. This subpart implements— (a) Section 1917(b)(1)(C) (iii)(VI) of the Social Security Act, (Act) which requires the issuer of a long-term care insurance...

Selective review of age-related needs of women with schizophrenia.

PubMed

Seeman, Mary V; Gupta, Rina

2015-04-01

Recognizing that needs differ between men and women with schizophrenia and that they vary over time, this review attempts to categorize the needs that are relevant to younger and to older women. This is a selective literature review focusing on topic areas the two authors determined to be most germane to women with schizophrenia. Articles were selected on the basis of currency, comprehensiveness, and study design. Particular attention was paid to the voices of the women themselves. There is considerable overlap between the needs of younger and older women with schizophrenia, but as a general rule, younger women require preventive strategies to stop the escalation of illness while older women require recovery interventions to regain lost hopes and abilities. There is clinical utility in cataloguing the needs of younger and older women with schizophrenia and conceptualizing interventions according to gender and age rather than viewing needed services along purely diagnostic lines.

A human reliability based usability evaluation method for safety-critical software

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boring, R. L.; Tran, T. Q.; Gertman, D. I.

2006-07-01

Boring and Gertman (2005) introduced a novel method that augments heuristic usability evaluation methods with that of the human reliability analysis method of SPAR-H. By assigning probabilistic modifiers to individual heuristics, it is possible to arrive at the usability error probability (UEP). Although this UEP is not a literal probability of error, it nonetheless provides a quantitative basis to heuristic evaluation. This method allows one to seamlessly prioritize and identify usability issues (i.e., a higher UEP requires more immediate fixes). However, the original version of this method required the usability evaluator to assign priority weights to the final UEP, thusmore » allowing the priority of a usability issue to differ among usability evaluators. The purpose of this paper is to explore an alternative approach to standardize the priority weighting of the UEP in an effort to improve the method's reliability. (authors)« less

Pharmaceutical strategy and innovation: an academics perspective.

PubMed

Baxendale, Ian R; Hayward, John J; Ley, Steven V; Tranmer, Geoffrey K

2007-06-01

The pharmaceutical industry is under increasing pressure on many fronts, from investors requiring larger returns to consumer groups and health authorities demanding cheaper and safer drugs. It is also feeling additional pressure from the infringement upon its profit margins by generic drug producers. Many companies are aggressively pursuing outsourcing contracts in an attempt to counter many of the financial pressures and streamline their operations. At the same time, the productivity of the pharmaceutical industry at its science base is being questioned in terms of the number of products and the timeframes required for each company to deliver them to market. This has generated uncertainties regarding the current corporate strategies that have been adopted and the levels of innovation being demonstrated. In this essay we discuss these topics in the context of the global pharmaceutical market, investigating the basis for many of these issues and highlighting the hurdles the industry needs to overcome, especially as they relate to the chemical sciences.

[Storage of plant protection products in farms: minimum safety requirements].

PubMed

Dutto, Moreno; Alfonzo, Santo; Rubbiani, Maristella

2012-01-01

Failure to comply with requirements for proper storage and use of pesticides in farms can be extremely hazardous and the risk of accidents involving farm workers, other persons and even animals is high. There are still wide differences in the interpretation of the concept of "securing or making safe", by workers in this sector. One of the critical points detected, particularly in the fruit sector, is the establishment of an adequate storage site for plant protection products. The definition of "safe storage of pesticides" is still unclear despite the recent enactment of Legislative Decree 81/2008 regulating health and work safety in Italy. In addition, there are no national guidelines setting clear minimum criteria for storage of plant protection products in farms. The authors, on the basis of their professional experience and through analysis of recent legislation, establish certain minimum safety standards for storage of pesticides in farms.

Comparison of effectiveness of convection-, transpiration-, and film-cooling methods with air as coolant

NASA Technical Reports Server (NTRS)

Eckert, E R G; Livingood, N B

1954-01-01

Various parts of aircraft propulsion engines that are in contact with hot gases often require cooling. Transpiration and film cooling, new methods that supposedly utilize cooling air more effectively than conventional convection cooling, have already been proposed. This report presents material necessary for a comparison of the cooling requirements of these three methods. Correlations that are regarded by the authors as the most reliable today are employed in evaluating each of the cooling processes. Calculations for the special case in which the gas velocity is constant along the cooled wall (flat plate) are presented. The calculations reveal that a comparison of the three cooling processes can be made on quite a general basis. The superiority of transpiration cooling is clearly shown for both laminar and turbulent flow. This superiority is reduced when the effects of radiation are included; for gas-turbine blades, however, there is evidence indicating that radiation may be neglected.

SME Acceptability Determination For DWPF Process Control (U)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Edwards, T.

2017-06-12

The statistical system described in this document is called the Product Composition Control System (PCCS). K. G. Brown and R. L. Postles were the originators and developers of this system as well as the authors of the first three versions of this technical basis document for PCCS. PCCS has guided acceptability decisions for the processing at the Defense Waste Processing Facility (DWPF) at the Savannah River Site (SRS) since the start of radioactive operations in 1996. The author of this revision to the document gratefully acknowledges the firm technical foundation that Brown and Postles established to support the ongoing successfulmore » operation at the DWPF. Their integration of the glass propertycomposition models, developed under the direction of C. M. Jantzen, into a coherent and robust control system, has served the DWPF well over the last 20+ years, even as new challenges, such as the introduction into the DWPF flowsheet of auxiliary streams from the Actinide Removal Process (ARP) and other processes, were met. The purpose of this revision is to provide a technical basis for modifications to PCCS required to support the introduction of waste streams from the Salt Waste Processing Facility (SWPF) into the DWPF flowsheet. An expanded glass composition region is anticipated by the introduction of waste streams from SWPF, and property-composition studies of that glass region have been conducted. Jantzen, once again, directed the development of glass property-composition models applicable for this expanded composition region. The author gratefully acknowledges the technical contributions of C.M. Jantzen leading to the development of these glass property-composition models. The integration of these models into the PCCS constraints necessary to administer future acceptability decisions for the processing at DWPF is provided by this sixth revision of this document.« less

41 CFR 302-9.500 - What means of transportation may we authorize for POV's?

Code of Federal Regulations, 2010 CFR

2010-07-01

... Federal Travel Regulation System RELOCATION ALLOWANCES TRANSPORTATION AND STORAGE OF PROPERTY 9-ALLOWANCES....500 What means of transportation may we authorize for POV's? You may authorize: (a) Commercial means...) Government means of transportation for POV's on a space-available basis. ...

Toward a scientifically rigorous basis for developing mapped ecological regions.

USGS Publications Warehouse

McMahon, G.; Wiken, E.B.; Gauthier, D.A.

2004-01-01

Despite the wide use of ecological regions in conservation and resource-management evaluations and assessments, a commonly accepted theoretical basis for ecological regionalization does not exist. This fact, along with the paucity of focus on ecological regionalization by professional associations, journals, and faculties, has inhibited the advancement of a broadly acceptable scientific basis for the development, use, and verification of ecological regions. The central contention of this article is that ecological regions should improve our understanding of geographic and ecological phenomena associated with biotic and abiotic processes occurring in individual regions and also of processes characteristic of interactions and dependencies among multiple regions. Research associated with any ecoregional framework should facilitate development of hypotheses about ecological phenomena and dominant landscape elements associated with these phenomena, how these phenomena are structured in space, and how they function in a hierarchy. Success in addressing the research recommendations outlined in this article cannot occur within an ad hoc, largely uncoordinated research environment. Successful implementation of this plan will require activities--coordination, funding, and education--that are both scientific and administrative in nature. Perhaps the most important element of an infrastructure to support the scientific work of ecoregionalization would be a national or international authority similar to the Water and Science Technology Board of the National Academy of Sciences.

Toward a Scientifically Rigorous Basis for Developing Mapped Ecological Regions

NASA Astrophysics Data System (ADS)

McMahon, Gerard; Wiken, Ed B.; Gauthier, David A.

2004-04-01

Despite the wide use of ecological regions in conservation and resource-management evaluations and assessments, a commonly accepted theoretical basis for ecological regionalization does not exist. This fact, along with the paucity of focus on ecological regionalization by professional associations, journals, and faculties, has inhibited the advancement of a broadly acceptable scientific basis for the development, use, and verification of ecological regions. The central contention of this article is that ecological regions should improve our understanding of geographic and ecological phenomena associated with biotic and abiotic processes occurring in individual regions and also of processes characteristic of interactions and dependencies among multiple regions. Research associated with any ecoregional framework should facilitate development of hypotheses about ecological phenomena and dominant landscape elements associated with these phenomena, how these phenomena are structured in space, and how they function in a hierarchy. Success in addressing the research recommendations outlined in this article cannot occur within an ad hoc, largely uncoordinated research environment. Successful implementation of this plan will require activities—coordination, funding, and education—that are both scientific and administrative in nature. Perhaps the most important element of an infrastructure to support the scientific work of ecoregionalization would be a national or international authority similar to the Water and Science Technology Board of the National Academy of Sciences.

12 CFR 543.11-1 - Grandfathered authority.

Code of Federal Regulations, 2011 CFR

2011-01-01

... upon the occurrence of specific preconditions, such as the attainment of a particular future date or... exercise of any particular authority on a more liberal basis than is allowable under the most liberal...

12 CFR 543.11-1 - Grandfathered authority.

Code of Federal Regulations, 2010 CFR

2010-01-01

... upon the occurrence of specific preconditions, such as the attainment of a particular future date or... exercise of any particular authority on a more liberal basis than is allowable under the most liberal...

31 CFR 587.507 - Provision of certain legal services authorized.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Provision of certain legal services authorized. 587.507 Section 587.507 Money and Finance: Treasury Regulations Relating to Money and Finance...-case basis authorizing receipt from unblocked sources of payment of professional fees and reimbursement...

10 CFR 765.20 - Procedures for submitting reimbursement claims.

Code of Federal Regulations, 2010 CFR

2010-01-01

... reclamation plan or other written authorization from NRC or an Agreement State upon which claims for... other written authorization, which is approved by NRC or an Agreement State, shall be included by the... reclamation plan or other written authorization, as modified or revised, shall serve as the basis for the...

40 CFR 79.54 - Tier 3.

Code of Federal Regulations, 2011 CFR

2011-07-01

... emission control equipment. (3) A manufacturer or group may be required to conduct biological and/or... Requiring Tier 3 Testing. (1) Tier 3 testing shall be required of a manufacturer or group of manufacturers... products. Tier 3 testing may be conducted either on an individual basis or a group basis. If performed on a...

40 CFR 79.54 - Tier 3.

Code of Federal Regulations, 2014 CFR

2014-07-01

... emission control equipment. (3) A manufacturer or group may be required to conduct biological and/or... Requiring Tier 3 Testing. (1) Tier 3 testing shall be required of a manufacturer or group of manufacturers... products. Tier 3 testing may be conducted either on an individual basis or a group basis. If performed on a...

40 CFR 79.54 - Tier 3.

Code of Federal Regulations, 2012 CFR

2012-07-01

... emission control equipment. (3) A manufacturer or group may be required to conduct biological and/or... Requiring Tier 3 Testing. (1) Tier 3 testing shall be required of a manufacturer or group of manufacturers... products. Tier 3 testing may be conducted either on an individual basis or a group basis. If performed on a...

40 CFR 79.54 - Tier 3.

Code of Federal Regulations, 2010 CFR

2010-07-01

... emission control equipment. (3) A manufacturer or group may be required to conduct biological and/or... Requiring Tier 3 Testing. (1) Tier 3 testing shall be required of a manufacturer or group of manufacturers... products. Tier 3 testing may be conducted either on an individual basis or a group basis. If performed on a...

40 CFR 79.54 - Tier 3.

Code of Federal Regulations, 2013 CFR

2013-07-01

... emission control equipment. (3) A manufacturer or group may be required to conduct biological and/or... Requiring Tier 3 Testing. (1) Tier 3 testing shall be required of a manufacturer or group of manufacturers... products. Tier 3 testing may be conducted either on an individual basis or a group basis. If performed on a...

77 FR 60114 - Agency Information Collection Activities Under OMB Review

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-02

... approximately 100 entities on a daily basis. The recordkeeping requirement of section 22.5 is expected to apply to approximately 100 entities on an approximately annual basis. Based on experience with analogous... required by section 22.2(g) is expected to require about 100 hours annually per entity, for a total burden...

Nondiscrimination on the basis of handicap; procedures and guidelines relating to health care for handicapped infants--HHS. Final rules.

PubMed

1984-01-12

These are final rules on procedures and guidelines relating to nondiscrimination on the basis of handicap in connection with health care for handicapped infants. These rules are issued under the authority of section 504 of the Rehabilitation Act of 1973, which prohibits discrimination on the basis of handicap in programs and activities receiving Federal financial assistance.

RTM user's guide

NASA Technical Reports Server (NTRS)

Claus, Steven J.; Loos, Alfred C.

1989-01-01

RTM is a FORTRAN '77 computer code which simulates the infiltration of textile reinforcements and the kinetics of thermosetting polymer resin systems. The computer code is based on the process simulation model developed by the author. The compaction of dry, woven textile composites is simulated to describe the increase in fiber volume fraction with increasing compaction pressure. Infiltration is assumed to follow D'Arcy's law for Newtonian viscous fluids. The chemical changes which occur in the resin during processing are simulated with a thermo-kinetics model. The computer code is discussed on the basis of the required input data, output files and some comments on how to interpret the results. An example problem is solved and a complete listing is included.

Collaborative communication: learning from advanced clinical practice patient consultations.

PubMed

Barratt, Julian

2018-04-28

Advanced nurse practitioners, and nurses aspiring to this role, are required to understand how to communicate effectively and on a collaborative basis with patients and carers during consultations, with the aim of enhancing patient outcomes such as improved patient satisfaction, ability to self-manage healthcare needs and adherence to care plans. This article explores collaborative communication in consultations and how best to achieve this, using the author's doctoral observational research based on the findings of a mixed methods observational study of communication in advanced clinical practice patient consultations. ©2018 RCN Publishing Company Ltd. All rights reserved. Not to be copied, transmitted or recorded in any way, in whole or part, without prior permission of the publishers.

Authorship and contribution disclosures

PubMed Central

Sauermann, Henry; Haeussler, Carolin

2017-01-01

Most scientific research is performed by teams, and for a long time, observers have inferred individual team members’ contributions by interpreting author order on published articles. In response to increasing concerns about this approach, journals are adopting policies that require the disclosure of individual authors’ contributions. However, it is not clear whether and how these disclosures improve upon the conventional approach. Moreover, there is little evidence on how contribution statements are written and how they are used by readers. We begin to address these questions in two studies. Guided by a conceptual model, Study 1 examines the relationship between author order and contribution statements on more than 12,000 articles to understand what information is provided by each. This analysis quantifies the risk of error when inferring contributions from author order and shows how this risk increases with team size and for certain types of authors. At the same time, the analysis suggests that some components of the value of contributions are reflected in author order but not in currently used contribution statements. Complementing the bibliometric analysis, Study 2 analyzes survey data from more than 6000 corresponding authors to examine how contribution statements are written and used. This analysis highlights important differences between fields and between senior versus junior scientists, as well as strongly diverging views about the benefits and limitations of contribution statements. On the basis of both studies, we highlight important avenues for future research and consider implications for a broad range of stakeholders. PMID:29152564

Fundamentals of financial statement analysis for academic physician managers.

PubMed

Danzi, J T; Boom, M L

1998-04-01

Academic medical centers (i.e., teaching hospitals) and academic medical practices are under pressure to control costs to compete with for-profit health care institutions. The authors explain how academic physician managers who want to control costs wisely must first understand the cost structure of the medical center or practice and compare that structure with those of for-profit institutions. Doing this requires a firm understanding of how to use a valuable tool, financial statement analysis, to assess an institution's health and performance. Such analysis consists of calculating a variety of financial ratios (e.g., operating income divided by revenues; net income divided by total assets) and then comparing them with the corresponding ratios that are considered industry norms. Three types of financial statements (defined in detail) lend themselves to this approach: the balance sheet, income statement, and statement of cash flows. The authors define standard financial ratios, point out their uses and limitations, and emphasize that a ratio's meaning derives from comparing it with the corresponding benchmark ratio in the industry as a whole. Ratios should be used not as the end point of assessing financial status, but as ways to identify possible problems that require further investigation. Analysis of trends of ratios over time within an institution is a complementary approach. The authors then discuss the use of ratios in three standard types of institutional evaluation: of performance, of liquidity and leverage, and of strategic planning. In addition, they present the financial statement of a fictitious academic medical center as an example of how to use ratios for financial statement analysis. The authors emphasize that the key to using the ratios they discuss and hundreds of others is first to decide what question needs answering and then to choose the relevant ratios to provide a basis for finding the answer.

The Genetic and Psychophysiolgical Basis of Antisocial Behavior: Implications for Counseling and Therapy.

ERIC Educational Resources Information Center

Raine, Adrian; Dunkin, Jennifer J.

1990-01-01

Argues that an understanding of the genetic and psychophysiological basis of crime and antisocial behavior has important implications for counselors dealing with antisocial behavior. Contends that psychophysiological factors interact with social factors in producing antisocial behaviors. (Author/ABL)

Rimonabant: marketing authorization suspended... at last: withdrawal. Half-measures.

PubMed

2009-04-01

Marketing authorization was granted for rimonabant on the basis of shaky data and despite poorly documented dangers. It took the EMEA 2 years to take action, by advising practitioners not to prescribe this drug.

Intensity of the Internal Standard Response as the Basis for Reporting a Test Specimen as Negative or Inconclusive

DTIC Science & Technology

2007-08-01

Documentation Page 1 . Report No. 2. Government Accession No. 3. Recipient’s Catalog No. DOT/FAA/AM-07/23 4. Title and Subtitle 5. Report Date...Organization Code 7. Author(s) 8. Performing Organization Report No. Ray H. Liu, 1 Chih-Hung Wu, 1 Yi-Jun Chen, 1 Chiung-Dan Chang, 1 Jason G...Investigation and the Office of Aerospace Medicine for sponsoring part of this research. 1 IntensIty of the Internal standard response as the BasIs

Academic psychiatry and managed care: a case study.

PubMed

Wetzler, S; Schwartz, B J; Sanderson, W; Karasu, T B

1997-08-01

An academic department of psychiatry in New York City eliminated the need for behavioral managed care intermediaries by transforming itself from a fee-for-service system to a system able to engage in full-risk capitation contracts. The first step was to require health maintenance organizations to contract directly with the department. The department formed two legal entities, a behavioral management services organization for utilization management and a behavioral integrated provider association. The authors describe these entities and review the first year of operation, presenting data on enrollees, capitation rates, and service utilization for the first three contracts. The fundamental differences in the treatment model under managed care and under a fee-for-service system are highlighted. The authors conclude that by contracting directly with insurers on a full-risk capitation basis, departments of psychiatry will be better able to face the economic threats posed by the cost constraints inherent in managed care and maintain or re-establish their autonomy as care managers as well as high-quality care providers.

[Criteria for determining the category of readiness for military service].

PubMed

Kulikov, V V; Liufing, A A; Panteleev, A Ia; Koval'skiĭ, O N

1997-12-01

In connection with professionalization of the Armed Forces of Russian Federation there was the necessity of deep study of laws and theoretical bases of the estimation criterion of readiness to the military service of various quota of military personnel. In this article the approaches to the given problem decision are reflected. The authors consider, that the military-medical examination represents complex process of study and estimation of the biomedical and social status of the person, definition of his conformity to conditions of the military service, the correlation of diseases and injuries with military service, but also sanction of other questions with removal of the written conclusion. The scientific development of the methodical approaches to definition of estimation of criteria of readiness category to the military service on the basis of priority of medical criteria over social in peace time becomes now one of the major problem of the military-medical examination. The authors discussed the methodological and theory questions of military-medical examination. These disputable questions require further discussion and scientific substantiation.

Acoustic signalling for mate attraction in crickets: Abdominal ganglia control the timing of the calling song pattern.

PubMed

Jacob, Pedro F; Hedwig, Berthold

2016-08-01

Decoding the neural basis of behaviour requires analysing how the nervous system is organised and how the temporal structure of motor patterns emerges from its activity. The stereotypical patterns of the calling song behaviour of male crickets, which consists of chirps and pulses, is an ideal model to study this question. We applied selective lesions to the abdominal nervous system of field crickets and performed long-term acoustic recordings of the songs. Specific lesions to connectives or ganglia abolish singing or reliably alter the temporal features of the chirps and pulses. Singing motor control appears to be organised in a modular and hierarchically fashion, where more posterior ganglia control the timing of the chirp pattern and structure and anterior ganglia the timing of the pulses. This modular organisation may provide the substrate for song variants underlying calling, courtship and rivalry behaviour and for the species-specific song patterns in extant crickets. Copyright © 2016 The Author(s). Published by Elsevier B.V. All rights reserved.

[Basic consideration on the security checking of sick travelers at airports].

PubMed

Felkai, Péter; Mártai, István

2012-09-02

The authorities guarantee the safety of passengers during air travel by strict ground security measures. All of these measures are restrictive and can affect the health status of both healthy and ill travelers. Patients who are in critical condition or confined to a stretcher and have to be repatriated by stretcher on a regular flight, must pass the airport security check as well. But the developers of security system should take into account the medical safety of patients during the procedure. The relevant medical principles are painfully missing not only in Hungary, but unfortunately also at most international airports. On the basis of principles reviewed in the present publication, an unambiguous, professionally reconciled regulation is necessary that would serve as a guideline for airport management and authorities, as well as for the involved medical personnel. Although setting principles into practice requires a different solution at each airport, yet, passenger safety and patient safety have to be harmonized as soon as possible.

The application of consequence models in risk assessment: A regulator`s view

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nussey, C.; Carter, D.A.; Cassidy, K.

1995-12-31

Quantified risk assessment (QRA) is a technique for aiding decision making. The UK Health and Safety Executive (HSE) uses QRA in the Major Hazards (MH) area to formulate advice to Local Planning Authorities (LPAs) on the siting of MH installations and the development of land in the vicinity of existing MH installations. The region around UK MH sites within which LPAs are required to consult HSE on land-use planning matters (i.e. the Consultation Distance (CD)) is increasingly being redefined by adopting a risk based approach. The authors are now in the process of conducting or updated site specific QRAs tomore » redefine CDs. This process enables them to identify risk reduction measures and discuss them with companies, taking into consideration the ALARP--as low as is reasonably practicable--philosophy. The paper outlines the basis of the QRAs and the role of consequence assessment models and procedures in this process, and illustrates by examples the setting of CDs and the application of the ALARP philosophy.« less

Two Hundred Thirty-Six Children With Developmental Hydrocephalus: Causes and Clinical Consequences.

PubMed

Tully, Hannah M; Ishak, Gisele E; Rue, Tessa C; Dempsey, Jennifer C; Browd, Samuel R; Millen, Kathleen J; Doherty, Dan; Dobyns, William B

2016-03-01

Few systematic assessments of developmental forms of hydrocephalus exist. We reviewed magnetic resonance images (MRIs) and clinical records of patients with infancy-onset hydrocephalus. Among 411 infants, 236 had hydrocephalus with no recognizable extrinsic cause. These children were assigned to 1 of 5 subtypes and compared on the basis of clinical characteristics and developmental and surgical outcomes. At an average age of 5.3 years, 72% of children were walking independently and 87% could eat by mouth; in addition, 18% had epilepsy. Distinct patterns of associated malformations and syndromes were observed within each subtype. On average, children with aqueductal obstruction, cysts, and encephaloceles had worse clinical outcomes than those with other forms of developmental hydrocephalus. Overall, 53% of surgically treated patients experienced at least 1 shunt failure, but hydrocephalus associated with posterior fossa crowding required fewer shunt revisions. We conclude that each subtype of developmental hydrocephalus is associated with distinct clinical characteristics, syndromology, and outcomes, suggesting differences in underlying mechanisms. © The Author(s) 2015.

How to be a good academic leader.

PubMed

Detsky, Allan S

2011-01-01

Individuals who take on leadership positions in academic health science centers help facilitate the mission of those institutions. However, they are often chosen on the basis of success in the core activities in research, education and patient care rather than on the basis of demonstrated leadership and management skills. Indeed, most academic leaders in the past have "learned on the job." This commentary provides practical advice on how to be an effective leader on the basis of the author's experiences as a Division Head and Chief of Medicine. It covers six themes (vision, managerial style, knowledge, people skills, organizational orientation and personal development) and offers 21 specific suggestions, one for each year of the author's leadership. It is hoped that this experience-derived advice will help future leaders in academic medicine.

Teaching authorship and publication practices in the biomedical and life sciences.

PubMed

Macrina, Francis L

2011-06-01

Examination of a limited number of publisher's Instructions for Authors, guidelines from two scientific societies, and the widely accepted policy document of the International Committee of Medical Journal Editors (ICMJE) provided useful information on authorship practices. Three of five journals examined (Nature, Science, and the Proceedings of the National Academy of Sciences) publish papers across a variety of disciplines. One is broadly focused on topics in medical research (New England Journal of Medicine) and one publishes research reports in a single discipline (Journal of Bacteriology). Similar elements of publication policy and accepted practices were found across the policies of these journals articulated in their Instructions for Authors. A number of these same elements were found in the professional society guidelines of the Society for Neuroscience and the American Chemical Society, as well as the ICMJE Uniform Requirements for Manuscripts Submitted to Biomedical Journals. Taken together, these sources provide the basis for articulating best practices in authorship in scientific research. Emerging from this material is a definition of authorship, as well as policy statements on duplicative publication, conflict of interest disclosure, electronic access, data sharing, digital image integrity, and research requiring subjects' protection, including prior registration of clinical trials. These common elements provide a foundation for teaching about scientific authorship and publication practices across biomedical and life sciences disciplines.

The Prosodic Basis of the Tiberian Hebrew System of Accents.

ERIC Educational Resources Information Center

Dresher, Bezalel Elan

1994-01-01

It is argued that the Tiberian system of accents that annotate the text of the Hebrew Bible has a prosodic basis. Tiberian representation can best be understood by integrating results of phonological, phonetic, and psycholinguistic research on prosodic structure. (93 references) (Author/LB)

28 CFR 0.29h - Specific authorities of the Inspector General.

Code of Federal Regulations, 2010 CFR

2010-07-01

... mismanagement, gross waste of funds, an abuse of authority, or a substantial and specific danger to the public... for carrying out the functions, powers, and duties of the OIG; (i) Employ on a temporary basis such... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Specific authorities of the Inspector...

Performance of NACA Eight-Stage Axial-Flow Compressor Designed on the Basis of Airfoil Theory

DTIC Science & Technology

1944-08-01

TEE BASIS OF AIRFOIL THEORY By John T. Slnnette, Jr., Oscar W. Schey, and J. Austin King Aircraft Engine Research Laboratory Cleveland, Ohio FILE...efficiency can he designed by the proper application of airfoil theory. Aircraft Engine Research laboratory, Hational Advisory Committee for Aeronautlos...Basis of Airfoil Theory AUTHORS): Sinnette, John T.; Schey, Oscar W.; and others ORIGINATING AGENCY: Aircraft Engine Research Laboratory, Cleveland

Skills development in the informal sector in India: The case of street food vendors

NASA Astrophysics Data System (ADS)

Pilz, Matthias; Uma, Gengaiah; Venkatram, Rengan

2015-04-01

The informal sector dominates India's economic life, so issues of skills development are particularly important. On the basis of a survey of 49 street food vendors in the Indian cities of New Delhi and Coimbatore, the authors of this article demonstrate that informal learning is a particularly significant form of vocational education and training. Vendors do not acquire skills in formal vocational education and training (VET) settings; for them, opportunities for learning on the job in family businesses or in informal employment are especially important. Unlike other studies, the authors' findings show that street food vendors have a wide range of specialist knowledge, skills and expertise required to conduct their business which they deploy profitably. These skills are not confined to preparing and selling food but also extend to areas such as price setting and marketing. All the street food vendors interviewed identified strongly with their occupation and expressed pride in it. Around half voiced a wish for further training. In this context, the authors suggest promoting non-formal learning settings geared explicitly to street food vendors' difficult working conditions. In line with a few other international innovative schemes, they term this a "non-formal apprenticeship" approach.

Rating the "Raters": Legal Exposure of Trustmark Authorities in the Context of Consumer Health Informatics

PubMed Central

Terry, Nicolas P

2000-01-01

There are three areas of potential legal exposure for an organization such as a trustmark authority involved in ehealth quality rating. First, an ehealth provider may make a complaint about negative or impliedly negative ratings rendered by the ratings body (false negative). Typically, a negative ratings complaint would rely on defamation or product disparagement causes of action. In some cases such complaints could be defended on the basis of absence of malice (US). Second, the rating body might render a positive rating on ehealth data that a third party allegedly relied upon and suffered injury (false positive). While the primary cause of action would be against the ehealth data provider, questions may arise as to possible liability of the trustmark authority. For example, some US liability exposure is possible based on cases involving the potential liability of product warrantors, trade associations and certifiers or endorsers. Third, a ratings body may face public law liability for its own web misfeasance. Several risk management approaches are possible and would not necessarily be mutually exclusive. These approaches will require careful investigation to assess their risk reduction potential and, in some cases, legislation.

Rating the Raters: Legal Exposure of Trustmark Authorities in the Context of Consumer Health Informatics

PubMed Central

2000-01-01

There are three areas of potential legal exposure for an organization such as a trustmark authority involved in e-health quality rating. First, an e-health provider may make a complaint about negative or impliedly negative ratings rendered by the ratings body (false negative). Typically, a negative ratings complaint would rely on defamation or product disparagement causes of action. In some cases such complaints could be defended on the basis of absence of malice (US). Second, the rating body might render a positive rating on e-health data that a third party allegedly relied upon and suffered injury (false positive). While the primary cause of action would be against the e-health data provider, questions may arise as to the possible liability of the trustmark authority. For example, some US liability exposure is possible based on cases involving the potential liability of product warrantors, trade associations, and certifiers or endorsers. Third, a ratings body may face public law liability for its own web misfeasance. Several risk management approaches are possible and would not necessarily be mutually exclusive. These approaches will require careful investigation to assess their risk reduction potential and, in some cases, the introduction of legislation. PMID:11720941

Baking soda as an abrasive in toothpastes: Mechanism of action and safety and effectiveness considerations.

PubMed

Hara, Anderson T; Turssi, Cecilia P

2017-11-01

Toothpastes can be formulated with different abrasive systems, depending on their intended clinical application. This formulation potentially affects their effectiveness and safety and, therefore, requires proper understanding. In this article, the authors focused on abrasive aspects of toothpastes containing sodium bicarbonate (baking soda), which have gained considerable attention because of their low abrasivity and good compatibility, while providing clinical effectiveness (further detailed in the other articles of this special issue). The authors first appraised the role of toothpaste abrasivity on tooth wear, exploring some underlying processes and the existing methods to determine toothpaste abrasivity. The authors reviewed the available data on the abrasivity of toothpastes containing baking soda and reported a summary of findings highlighting the clinical implications. On the basis of the collected evidence, baking soda has an intrinsic low-abrasive nature because of its comparatively lower hardness in relation to enamel and dentin. Baking soda toothpastes also may contain other ingredients, which can increase their stain removal effectiveness and, consequently, abrasivity. Even those formulations have abrasivity well within the safety limit regulatory agencies have established and, therefore, can be considered safe. Copyright © 2017 American Dental Association. Published by Elsevier Inc. All rights reserved.

Rating the raters: legal exposure of trustmark authorities in the context of consumer health informatics.

PubMed

Terry, N P

2000-01-01

There are three areas of potential legal exposure for an organization such as a trustmark authority involved in e-health quality rating. First, an e-health provider may make a complaint about negative or impliedly negative ratings rendered by the ratings body (false negative). Typically, a negative ratings complaint would rely on defamation or product disparagement causes of action. In some cases such complaints could be defended on the basis of absence of malice (US). Second, the rating body might render a positive rating on e-health data that a third party allegedly relied upon and suffered injury (false positive). While the primary cause of action would be against the e-health data provider, questions may arise as to the possible liability of the trustmark authority. For example, some US liability exposure is possible based on cases involving the potential liability of product warrantors, trade associations, and certifiers or endorsers. Third, a ratings body may face public law liability for its own web misfeasance. Several risk management approaches are possible and would not necessarily be mutually exclusive. These approaches will require careful investigation to assess their risk reduction potential and, in some cases, the introduction of legislation.

Protecting the Environment Through Public Procurement Law - The Case of Poland

NASA Astrophysics Data System (ADS)

Kozik, Renata; Karasińska-Jaśkowiec, Izabela

2016-10-01

The article presents the results of studies whose aim was to analyse public procurement procedures in the context of environmental protection, especially wastewater infrastructure, performed in the selected Polish municipalities. The selection criterions were the time of public procurement procedure - from 2009 until 2015 and that the contract was cofinanced by the European Union funds. The contracting authorities responsible for awarding specific contracts, were asked series of detailed questions about the environmental criteria and requirements contained in the tender documents for the construction contracts related to the wastewater infrastructure. The aim of the detailed study was to determine whether the actions taken by the contracting authorities in a tender procedure for the construction or operation of wastewater infrastructure include environmental issues. Authors examine also the applicable public procurement law regulation in Poland and Europe in the context of sustainable development and environmental protection. The study of public procurement law was to check whether the law regulation fully takes into account the environmental aspects of the planned investments. On this basis, conclusions have been made that laws are consistent and do not constitute an obstacle to awarding a contract positively affecting the environment.

Standing sedation in African elephants (Loxodonta africana) using detomidine-butorphanol combinations.

PubMed

Neiffer, Donald L; Miller, Michele A; Weber, Martha; Stetter, Mark; Fontenot, Deidre K; Robbins, P K; Pye, Geoffrey W

2005-06-01

Standing sedation was provided for 14 clinical procedures in three African elephants (Loxodonta africana) managed by combined protected and modified-protected contact and trained through operant conditioning. An initial hand-injection of detomidine hydrochloride and butorphanol tartrate at a ratio of 1:1 on a microg:microg basis was administered intramuscularly, with a dosage range of 50-70 mg (12.9-19.7 microg/kg) for each drug. The initial injection resulted in adequate sedation for initiation and completion of eight procedures, whereas supplemental doses were required for the remaining procedures. The dosage range for the supplemental injections of each drug was 4.0-7.3 microg/kg. Initial effect was noted within 3.0-25 min (mean = 11.6 min, SD +/- 5.9 min), with maximal effect occurring at 25-30 min for those procedures not requiring supplementation. In all but one procedure, this effect was maintained until the end of the procedure, which ranged from 47 to 98 min (mean = 74.7 min, SD +/- 18.8 min). No cardiac or respiratory depression was appreciated. Recovery after administration of reversal agents was rapid and complete, ranging from 2 to 20 min (mean = 9.0 min, SD +/- 7.0 min). On the basis of the authors' experience, recommended dosage ranges for reversal agents would be intravenous yohimbine (73.4-98.5 microg/kg), intravenous naltrexone (48.9-98.5 microg/kg), and intramuscular naltrexone (73.4-98.5 microg/kg). Approximately one-third to one-half of the total naltrexone dose should be administered intravenously. Mild adverse side effects limited to the gastrointestinal tract were observed in association with five procedures including abdominal distention with or without transient anorexia. Administration of reversal agents, encouraging exercise and water consumption, and administration of flunixin meglumine were helpful in the resolution of signs. In addition to gastrointestinal signs, slight ataxia was observed before initiation of surgical stimulation during one procedure in which 19.7 microg/kg of each drug was administered. On the basis of the procedures that did not require supplementation to initiate treatment and taking into consideration the potential for ataxia at higher doses, a starting dosage range of 14.7-16.2 microg/kg of both detomidine and butorphanol in a ratio of 1:1 on a microg:microg basis administered i.m. simultaneously is recommended.

10 CFR 830.202 - Safety basis.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Safety basis. 830.202 Section 830.202 Energy DEPARTMENT OF ENERGY NUCLEAR SAFETY MANAGEMENT Safety Basis Requirements § 830.202 Safety basis. (a) The contractor responsible for a hazard category 1, 2, or 3 DOE nuclear facility must establish and maintain the safety basis...

10 CFR 830.202 - Safety basis.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Safety basis. 830.202 Section 830.202 Energy DEPARTMENT OF ENERGY NUCLEAR SAFETY MANAGEMENT Safety Basis Requirements § 830.202 Safety basis. (a) The contractor responsible for a hazard category 1, 2, or 3 DOE nuclear facility must establish and maintain the safety basis...

45 CFR 149.1 - Purpose and basis.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 1 2011-10-01 2011-10-01 false Purpose and basis. 149.1 Section 149.1 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS REQUIREMENTS... Affordable Care Act (Pub. L. 111-148). ...

45 CFR 149.1 - Purpose and basis.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Purpose and basis. 149.1 Section 149.1 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS REQUIREMENTS... Affordable Care Act (Pub. L. 111-148). ...

[The modern patient in conditions of globalization].

PubMed

Jiliyayeva, Ye P

2013-01-01

The article makes an attempt to detect main characteristics of status of modern patient on the basis of analysis of Russian and international materials. Nowadays, patient plays an active role both in process of receiving medical care and in issues of health policy and public health. The patient has many rights and modes to defend them. At the national and international levels, many organizations of patients exist and their authority and impact only increase. The globalization effects on structure of patients, because it brought facilitation of trans-borders travel and resulted in development of medical tourism and increase of migration. The structure of patients becomes more various in its national and ethnic belonging, cultural and language characteristics. This trend generated new requirements to training of medical personnel and functioning of health services. The globalization also enhances social economic inequity between patients and hence complicates accessibility of high quality medical care to population. The main traits of modern patient are to be studied and analyzed on all levels with purpose to develop an important basis for successful planning, reformation and development of public health.

29 CFR 1975.2 - Basis of authority.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) COVERAGE OF EMPLOYERS UNDER THE WILLIAMS-STEIGER OCCUPATIONAL SAFETY AND HEALTH ACT OF 1970 § 1975.2 Basis... Occupational Safety and Health Act of 1970, is derived mainly from the Commerce Clause of the Constitution...

The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription.

PubMed

Akay, Alper; Di Domenico, Tomas; Suen, Kin M; Nabih, Amena; Parada, Guillermo E; Larance, Mark; Medhi, Ragini; Berkyurek, Ahmet C; Zhang, Xinlian; Wedeles, Christopher J; Rudolph, Konrad L M; Engelhardt, Jan; Hemberg, Martin; Ma, Ping; Lamond, Angus I; Claycomb, Julie M; Miska, Eric A

2017-08-07

Small RNAs play a crucial role in genome defense against transposable elements and guide Argonaute proteins to nascent RNA transcripts to induce co-transcriptional gene silencing. However, the molecular basis of this process remains unknown. Here, we identify the conserved RNA helicase Aquarius/EMB-4 as a direct and essential link between small RNA pathways and the transcriptional machinery in Caenorhabditis elegans. Aquarius physically interacts with the germline Argonaute HRDE-1. Aquarius is required to initiate small-RNA-induced heritable gene silencing. HRDE-1 and Aquarius silence overlapping sets of genes and transposable elements. Surprisingly, removal of introns from a target gene abolishes the requirement for Aquarius, but not HRDE-1, for small RNA-dependent gene silencing. We conclude that Aquarius allows small RNA pathways to compete for access to nascent transcripts undergoing co-transcriptional splicing in order to detect and silence transposable elements. Thus, Aquarius and HRDE-1 act as gatekeepers coordinating gene expression and genome defense. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

A Deficit in Older Adults' Effortful Selection of Cued Responses

PubMed Central

Proctor, Robert W.; Vu, Kim-Phuong L.; Pick, David F.

2007-01-01

J. J. Adam et al. (1998) provided evidence for an “age-related deficit in preparing 2 fingers on 2 hands, but not on 1 hand” (p. 870). Instead of having an anatomical basis, the deficit could result from the effortful processing required for individuals to select cued subsets of responses that do not coincide with left and right subgroups. The deficit also could involve either the ultimate benefit that can be attained or the time required to attain that benefit. The authors report 3 experiments (Ns = 40, 48, and 32 participants, respectively) in which they tested those distinctions by using an overlapped hand placement (participants alternated the index and middle fingers of the hands), a normal hand placement, and longer precuing intervals than were used in previous studies. The older adults were able to achieve the full precuing benefit shown by younger adults but required longer to achieve the maximal benefit for most pairs of responses. The deficit did not depend on whether the responses were from different hands, suggesting that it lies primarily in the effortful processing required for those subsets of cued responses that are not selected easily. PMID:16801319

10 CFR 830.200 - Scope.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Scope. 830.200 Section 830.200 Energy DEPARTMENT OF ENERGY NUCLEAR SAFETY MANAGEMENT Safety Basis Requirements § 830.200 Scope. This Subpart establishes safety basis requirements for hazard category 1, 2, and 3 DOE nuclear facilities. ...

45 CFR 154.101 - Basis and scope.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Welfare Department of Health and Human Services REQUIREMENTS RELATING TO HEALTH CARE ACCESS HEALTH... scope. (a) Basis. This part implements section 2794 of the Public Health Service (PHS) Act. (b) Scope. This part establishes the requirements for health insurance issuers offering health insurance coverage...

45 CFR 154.101 - Basis and scope.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS HEALTH... scope. (a) Basis. This part implements section 2794 of the Public Health Service (PHS) Act. (b) Scope. This part establishes the requirements for health insurance issuers offering health insurance coverage...

45 CFR 148.101 - Basis and purpose.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Welfare Department of Health and Human Services REQUIREMENTS RELATING TO HEALTH CARE ACCESS REQUIREMENTS FOR THE INDIVIDUAL HEALTH INSURANCE MARKET General Provisions § 148.101 Basis and purpose. This part... individuals and family members who have, or seek, individual health insurance coverage from discrimination...

45 CFR 154.101 - Basis and scope.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS HEALTH... scope. (a) Basis. This part implements section 2794 of the Public Health Service (PHS) Act. (b) Scope. This part establishes the requirements for health insurance issuers offering health insurance coverage...

45 CFR 154.101 - Basis and scope.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS HEALTH... scope. (a) Basis. This part implements section 2794 of the Public Health Service (PHS) Act. (b) Scope. This part establishes the requirements for health insurance issuers offering health insurance coverage...

10 CFR 830.200 - Scope.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Scope. 830.200 Section 830.200 Energy DEPARTMENT OF ENERGY NUCLEAR SAFETY MANAGEMENT Safety Basis Requirements § 830.200 Scope. This Subpart establishes safety basis requirements for hazard category 1, 2, and 3 DOE nuclear facilities. ...

10 CFR 830.200 - Scope.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Scope. 830.200 Section 830.200 Energy DEPARTMENT OF ENERGY NUCLEAR SAFETY MANAGEMENT Safety Basis Requirements § 830.200 Scope. This Subpart establishes safety basis requirements for hazard category 1, 2, and 3 DOE nuclear facilities. ...

10 CFR 830.200 - Scope.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Scope. 830.200 Section 830.200 Energy DEPARTMENT OF ENERGY NUCLEAR SAFETY MANAGEMENT Safety Basis Requirements § 830.200 Scope. This Subpart establishes safety basis requirements for hazard category 1, 2, and 3 DOE nuclear facilities. ...

10 CFR 50.10 - License required; limited work authorization.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false License required; limited work authorization. 50.10... FACILITIES Requirement of License, Exceptions § 50.10 License required; limited work authorization. (a... permit, early site permit authorizing limited work authorization activities, combined license, or limited...

10 CFR Appendix C to Part 73 - Nuclear Power Plant Safeguards Contingency Plans

Code of Federal Regulations, 2013 CFR

2013-01-01

... command and delegation of authority as these apply to safeguards contingencies. b. Physical Layout—(i..., up to and including the design basis threat of radiological sabotage. The goals of licensee... general description of how the response is organized. a. Perceived Danger—Consistent with the design basis...

Identifying Psychopathy Subtypes on the Basis of Personality Structure

ERIC Educational Resources Information Center

Hicks, Brian M.; Markon, Kristian E.; Patrick, Christopher J.; Krueger, Robert F.; Newman, Joseph P.

2004-01-01

The authors used model-based cluster analysis to identify subtypes of criminal psychopaths on the basis of differences in personality structure. Participants included 96 male prisoners diagnosed as psychopathic, using the Psychopathy Checklist Revised (PCL-R; R. D. Hare, 1991). Personality was assessed using the brief form of the Multidimensional…

42 CFR 1004.90 - Basis for recommended sanction.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 5 2010-10-01 2010-10-01 false Basis for recommended sanction. 1004.90 Section 1004.90 Public Health OFFICE OF INSPECTOR GENERAL-HEALTH CARE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OIG AUTHORITIES IMPOSITION OF SANCTIONS ON HEALTH CARE PRACTITIONERS AND PROVIDERS OF HEALTH CARE...

The Effect of Birth Order on Roommate Compatibility

ERIC Educational Resources Information Center

Schuh, John H.; Williams, Ondre J.

1977-01-01

A group of students were matched on the basis of compatible birth order; another was matched on the basis of conflicting birth order. After a month's experience in a residence hall their compatibility was examined. Students with conflicting birth order were more compatible than those with the same birth order. (Author)

45 CFR 402.30 - Basis of awards.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false Basis of awards. 402.30 Section 402.30 Public Welfare Regulations Relating to Public Welfare OFFICE OF REFUGEE RESETTLEMENT, ADMINISTRATION FOR CHILDREN... award constitutes the authority to draw and expend funds for the purposes set forth in the Act and this...

22 CFR 229.415 - Access to course offerings.

Code of Federal Regulations, 2013 CFR

2013-04-01

....415 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex... on the basis of sex, or require or refuse participation therein by any of its students on such basis...

22 CFR 229.415 - Access to course offerings.

Code of Federal Regulations, 2014 CFR

2014-04-01

....415 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex... on the basis of sex, or require or refuse participation therein by any of its students on such basis...

22 CFR 229.415 - Access to course offerings.

Code of Federal Regulations, 2011 CFR

2011-04-01

....415 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex... on the basis of sex, or require or refuse participation therein by any of its students on such basis...

22 CFR 229.415 - Access to course offerings.

Code of Federal Regulations, 2012 CFR

2012-04-01

....415 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex... on the basis of sex, or require or refuse participation therein by any of its students on such basis...

42 CFR 493.563 - Validation inspections-Basis and focus.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 5 2010-10-01 2010-10-01 false Validation inspections-Basis and focus. 493.563... Validation inspections—Basis and focus. (a) Basis for validation inspection—(1) Laboratory with a certificate... of that State's licensed or approved laboratories from CLIA program requirements. (b) Validation...

42 CFR 493.563 - Validation inspections-Basis and focus.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 5 2012-10-01 2012-10-01 false Validation inspections-Basis and focus. 493.563... Validation inspections—Basis and focus. (a) Basis for validation inspection—(1) Laboratory with a certificate... of that State's licensed or approved laboratories from CLIA program requirements. (b) Validation...

42 CFR 493.563 - Validation inspections-Basis and focus.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 5 2013-10-01 2013-10-01 false Validation inspections-Basis and focus. 493.563... Validation inspections—Basis and focus. (a) Basis for validation inspection—(1) Laboratory with a certificate... of that State's licensed or approved laboratories from CLIA program requirements. (b) Validation...

42 CFR 493.563 - Validation inspections-Basis and focus.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 5 2014-10-01 2014-10-01 false Validation inspections-Basis and focus. 493.563... Validation inspections—Basis and focus. (a) Basis for validation inspection—(1) Laboratory with a certificate... of that State's licensed or approved laboratories from CLIA program requirements. (b) Validation...

42 CFR 493.563 - Validation inspections-Basis and focus.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 5 2011-10-01 2011-10-01 false Validation inspections-Basis and focus. 493.563... Validation inspections—Basis and focus. (a) Basis for validation inspection—(1) Laboratory with a certificate... of that State's licensed or approved laboratories from CLIA program requirements. (b) Validation...

45 CFR 144.101 - Basis and purpose.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS REQUIREMENTS RELATING TO HEALTH INSURANCE COVERAGE General Provisions § 144.101 Basis and purpose. (a) Part 146 of this... is to improve access to individual health insurance coverage for certain individuals who previously...

45 CFR 144.101 - Basis and purpose.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS REQUIREMENTS RELATING TO HEALTH INSURANCE COVERAGE General Provisions § 144.101 Basis and purpose. (a) Part 146 of this... is to improve access to individual health insurance coverage for certain individuals who previously...

45 CFR 144.101 - Basis and purpose.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Welfare Department of Health and Human Services REQUIREMENTS RELATING TO HEALTH CARE ACCESS REQUIREMENTS RELATING TO HEALTH INSURANCE COVERAGE General Provisions § 144.101 Basis and purpose. (a) Part 146 of this... is to improve access to individual health insurance coverage for certain individuals who previously...

A visualization method for teaching the geometric design of highways

DOT National Transportation Integrated Search

2000-04-11

In this project the authors employed state-of-the-art technology for developing visualization tools for teaching highway design. Specifically, the authors used photolog images as the basis for developing dynamic 3-D models of selected geometric eleme...

An Investigation of the Characteristics of the Enzyme Thrombin, Suitable for Classwork

ERIC Educational Resources Information Center

Blofield, B. Ann

1972-01-01

Shows how a simple investigation of the enzyme, thrombin, can provide a series of experiments giving information on enzyme characteristics. The results also provide a basis for discussion of the coagulation mechanism and related phenomena. (Author/AL)

77 FR 74775 - Drawbridge Operation Regulation; Sacramento River, CA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-18

... held. B. Basis and Purpose The Freeport Drawbridge is a swing span style drawbridge at mile 46.0, over.... The authority citation for part 117 continues to read as follows: Authority: 33 U.S.C. 499; 33 CFR 1...

41 CFR 101-8.304 - Effect of State or local law or other requirements and effect of employment opportunities.

Code of Federal Regulations, 2010 CFR

2010-07-01

... REGULATIONS GENERAL 8-NONDISCRIMINATION IN PROGRAMS RECEIVING FEDERAL FINANCIAL ASSISTANCE 8.3-Discrimination Prohibited on the Basis of Handicap § 101-8.304 Effect of State or local law or other requirements and effect... alleviated by the existence of any State or local law or other requirement that, on the basis of handicap...

41 CFR 101-8.304 - Effect of State or local law or other requirements and effect of employment opportunities.

Code of Federal Regulations, 2014 CFR

2014-07-01

... REGULATIONS GENERAL 8-NONDISCRIMINATION IN PROGRAMS RECEIVING FEDERAL FINANCIAL ASSISTANCE 8.3-Discrimination Prohibited on the Basis of Handicap § 101-8.304 Effect of State or local law or other requirements and effect... alleviated by the existence of any State or local law or other requirement that, on the basis of handicap...

41 CFR 101-8.304 - Effect of State or local law or other requirements and effect of employment opportunities.

Code of Federal Regulations, 2013 CFR

2013-07-01

... REGULATIONS GENERAL 8-NONDISCRIMINATION IN PROGRAMS RECEIVING FEDERAL FINANCIAL ASSISTANCE 8.3-Discrimination Prohibited on the Basis of Handicap § 101-8.304 Effect of State or local law or other requirements and effect... alleviated by the existence of any State or local law or other requirement that, on the basis of handicap...

41 CFR 101-8.304 - Effect of State or local law or other requirements and effect of employment opportunities.

Code of Federal Regulations, 2011 CFR

2011-07-01

... REGULATIONS GENERAL 8-NONDISCRIMINATION IN PROGRAMS RECEIVING FEDERAL FINANCIAL ASSISTANCE 8.3-Discrimination Prohibited on the Basis of Handicap § 101-8.304 Effect of State or local law or other requirements and effect... alleviated by the existence of any State or local law or other requirement that, on the basis of handicap...

41 CFR 101-8.304 - Effect of State or local law or other requirements and effect of employment opportunities.

Code of Federal Regulations, 2012 CFR

2012-07-01

... REGULATIONS GENERAL 8-NONDISCRIMINATION IN PROGRAMS RECEIVING FEDERAL FINANCIAL ASSISTANCE 8.3-Discrimination Prohibited on the Basis of Handicap § 101-8.304 Effect of State or local law or other requirements and effect... alleviated by the existence of any State or local law or other requirement that, on the basis of handicap...

45 CFR 157.10 - Basis and scope.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 1 2014-10-01 2014-10-01 false Basis and scope. 157.10 Section 157.10 Public Welfare Department of Health and Human Services REQUIREMENTS RELATING TO HEALTH CARE ACCESS EMPLOYER INTERACTIONS WITH EXCHANGES AND SHOP PARTICIPATION General Provisions § 157.10 Basis and scope. (a) Basis. This...

45 CFR 157.10 - Basis and scope.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 1 2013-10-01 2013-10-01 false Basis and scope. 157.10 Section 157.10 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS EMPLOYER INTERACTIONS WITH EXCHANGES AND SHOP PARTICIPATION General Provisions § 157.10 Basis and scope. (a) Basis. This...

45 CFR 157.10 - Basis and scope.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 1 2012-10-01 2012-10-01 false Basis and scope. 157.10 Section 157.10 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS EMPLOYER INTERACTIONS WITH EXCHANGES AND SHOP PARTICIPATION General Provisions § 157.10 Basis and scope. (a) Basis. This...

22 CFR 146.415 - Access to course offerings.

Code of Federal Regulations, 2011 CFR

2011-04-01

....415 Foreign Relations DEPARTMENT OF STATE CIVIL RIGHTS NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex... on the basis of sex, or require or refuse participation therein by any of its students on such basis...

22 CFR 146.415 - Access to course offerings.

Code of Federal Regulations, 2014 CFR

2014-04-01

....415 Foreign Relations DEPARTMENT OF STATE CIVIL RIGHTS NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex... on the basis of sex, or require or refuse participation therein by any of its students on such basis...

22 CFR 146.415 - Access to course offerings.

Code of Federal Regulations, 2012 CFR

2012-04-01

....415 Foreign Relations DEPARTMENT OF STATE CIVIL RIGHTS NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex... on the basis of sex, or require or refuse participation therein by any of its students on such basis...

22 CFR 146.415 - Access to course offerings.

Code of Federal Regulations, 2013 CFR

2013-04-01

....415 Foreign Relations DEPARTMENT OF STATE CIVIL RIGHTS NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex... on the basis of sex, or require or refuse participation therein by any of its students on such basis...

[On risk-oriented model of sanitary epidemiologic surveillance in occupational hygiene].

PubMed

Zaitseval, N V; Mai, I V; Kostarev, V G; Bashketova, N S

2015-01-01

In 2015, Federal Service on surveillance in consumers rights protection and public well-being set a task to organize planned work of regional agencies on basis of risk-oriented model of control and supervision. Based on results of pilot project in Rospotrebnadzor Department of Perm area and St-Petersburg, the article covers methodic approaches to classification of objects liable to surveillance in occupational hygiene. The classification considers possibility of sanitary law violation, severity of this violation consequences and number of workers exposed to risk factors including hazardous work conditions. The authors specified recommendations on periodicity and forms of planned inspections considering evaluation of potential risk for human health, determined problems that require solution in implementation of risk-oriented model of surveillance.

[Cardiac tamponade disclosing systemic lupus erythematosus].

PubMed

Nour-Eddine, M; Bennis, A; Soulami, S; Chraibi, N

1996-02-01

Cardiac tamponade secondary to systemic lupus erythematosus is rare and has a very serious prognosis. The authors report a case of cardiac tamponade confirmed by echocardiography, which constituted the presenting sign of systemic lupus erythematosus in a 20-year-old patient, who required emergency pericardial aspiration. The diagnosis of systemic lupus erythematosus was established on the basis of the combination of pericardial involvement, non-erosive arthritis, leukopenia with lymphopenia, presence of LE cells and anti-native DNA antibodies and positive antinuclear antibody titre of 1/2560. The clinical course was favourable in response to 3 months of corticosteroid treatment. The possibility of SLE should be considered in any case of cardiac tamponade in a young patient in which the aetiology is not explained.

45 CFR 147.100 - Basis and scope.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS HEALTH INSURANCE REFORM REQUIREMENTS FOR THE GROUP AND INDIVIDUAL HEALTH INSURANCE MARKETS § 147.100 Basis and... Care Act that apply to group health plans and health insurance issuers in the Group and Individual...

45 CFR 147.100 - Basis and scope.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS HEALTH INSURANCE REFORM REQUIREMENTS FOR THE GROUP AND INDIVIDUAL HEALTH INSURANCE MARKETS § 147.100 Basis and... Care Act that apply to group health plans and health insurance issuers in the Group and Individual...

45 CFR 147.100 - Basis and scope.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Welfare Department of Health and Human Services REQUIREMENTS RELATING TO HEALTH CARE ACCESS HEALTH INSURANCE REFORM REQUIREMENTS FOR THE GROUP AND INDIVIDUAL HEALTH INSURANCE MARKETS § 147.100 Basis and... Care Act that apply to group health plans and health insurance issuers in the Group and Individual...

45 CFR 147.100 - Basis and scope.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS HEALTH INSURANCE REFORM REQUIREMENTS FOR THE GROUP AND INDIVIDUAL HEALTH INSURANCE MARKETS § 147.100 Basis and... Care Act that apply to group health plans and health insurance issuers in the Group and Individual...

45 CFR 147.100 - Basis and scope.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS HEALTH INSURANCE REFORM REQUIREMENTS FOR THE GROUP AND INDIVIDUAL HEALTH INSURANCE MARKETS § 147.100 Basis and... Care Act that apply to group health plans and health insurance issuers in the Group and Individual...

48 CFR 239.7405 - Delegated authority for telecommunications resources.

Code of Federal Regulations, 2011 CFR

2011-10-01

... telecommunications resources. 239.7405 Section 239.7405 Federal Acquisition Regulations System DEFENSE ACQUISITION... TECHNOLOGY Telecommunications Services 239.7405 Delegated authority for telecommunications resources. The contracting officer may enter into a telecommunications service contract on a month-to-month basis or for any...

48 CFR 239.7405 - Delegated authority for telecommunications resources.

Code of Federal Regulations, 2010 CFR

2010-10-01

... telecommunications resources. 239.7405 Section 239.7405 Federal Acquisition Regulations System DEFENSE ACQUISITION... TECHNOLOGY Telecommunications Services 239.7405 Delegated authority for telecommunications resources. The contracting officer may enter into a telecommunications service contract on a month-to-month basis or for any...

48 CFR 239.7405 - Delegated authority for telecommunications resources.

Code of Federal Regulations, 2012 CFR

2012-10-01

... telecommunications resources. 239.7405 Section 239.7405 Federal Acquisition Regulations System DEFENSE ACQUISITION... TECHNOLOGY Telecommunications Services 239.7405 Delegated authority for telecommunications resources. The contracting officer may enter into a telecommunications service contract on a month-to-month basis or for any...

48 CFR 239.7405 - Delegated authority for telecommunications resources.

Code of Federal Regulations, 2013 CFR

2013-10-01

... telecommunications resources. 239.7405 Section 239.7405 Federal Acquisition Regulations System DEFENSE ACQUISITION... TECHNOLOGY Telecommunications Services 239.7405 Delegated authority for telecommunications resources. The contracting officer may enter into a telecommunications service contract on a month-to-month basis or for any...

48 CFR 239.7405 - Delegated authority for telecommunications resources.

Code of Federal Regulations, 2014 CFR

2014-10-01

... telecommunications resources. 239.7405 Section 239.7405 Federal Acquisition Regulations System DEFENSE ACQUISITION... TECHNOLOGY Telecommunications Services 239.7405 Delegated authority for telecommunications resources. The contracting officer may enter into a telecommunications service contract on a month-to-month basis or for any...

5 CFR 2416.160 - Communications.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Communications. 2416.160 Section 2416.160 Administrative Personnel FEDERAL LABOR RELATIONS AUTHORITY, GENERAL COUNSEL OF THE FEDERAL LABOR RELATIONS... BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE FEDERAL LABOR RELATIONS AUTHORITY § 2416...

45 CFR 148.101 - Basis and purpose.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 1 2011-10-01 2011-10-01 false Basis and purpose. 148.101 Section 148.101 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS REQUIREMENTS... protections for mothers and newborns with respect to coverage for hospital stays in connection with childbirth...

45 CFR 148.101 - Basis and purpose.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS REQUIREMENTS FOR THE INDIVIDUAL HEALTH INSURANCE MARKET General Provisions § 148.101 Basis and purpose. This part implements sections 2741 through 2763 and 2791 and 2792 of the PHS Act. Its purpose is to improve access to...

45 CFR 148.101 - Basis and purpose.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS REQUIREMENTS FOR THE INDIVIDUAL HEALTH INSURANCE MARKET General Provisions § 148.101 Basis and purpose. This part implements sections 2741 through 2763 and 2791 and 2792 of the PHS Act. Its purpose is to improve access to...

School closure as an influenza mitigation strategy: how variations in legal authority and plan criteria can alter the impact.

PubMed

Potter, Margaret A; Brown, Shawn T; Cooley, Phillip C; Sweeney, Patricia M; Hershey, Tina B; Gleason, Sherrianne M; Lee, Bruce Y; Keane, Christopher R; Grefenstette, John; Burke, Donald S

2012-11-14

States' pandemic influenza plans and school closure statutes are intended to guide state and local officials, but most faced a great deal of uncertainty during the 2009 influenza H1N1 epidemic. Questions remained about whether, when, and for how long to close schools and about which agencies and officials had legal authority over school closures. This study began with analysis of states' school-closure statutes and pandemic influenza plans to identify the variations among them. An agent-based model of one state was used to represent as constants a population's demographics, commuting patterns, work and school attendance, and community mixing patterns while repeated simulations explored the effects of variations in school closure authority, duration, closure thresholds, and reopening criteria. The results show no basis on which to justify statewide rather than school-specific or community-specific authority for school closures. Nor do these simulations offer evidence to require school closures promptly at the earliest stage of an epidemic. More important are criteria based on monitoring of local case incidence and on authority to sustain closure periods sufficiently to achieve epidemic mitigation. This agent-based simulation suggests several ways to improve statutes and influenza plans. First, school closure should remain available to state and local authorities as an influenza mitigation strategy. Second, influenza plans need not necessarily specify the threshold for school closures but should clearly define provisions for early and ongoing local monitoring. Finally, school closure authority may be exercised at the statewide or local level, so long as decisions are informed by monitoring incidence in local communities and schools.

Using an expanding nondirect product harmonic basis with an iterative eigensolver to compute vibrational energy levels with as many as seven atoms.

PubMed

Brown, James; Carrington, Tucker

2016-10-14

We demonstrate that it is possible to use a variational method to compute 50 vibrational levels of ethylene oxide (a seven-atom molecule) with convergence errors less than 0.01 cm -1 . This is done by beginning with a small basis and expanding it to include product basis functions that are deemed to be important. For ethylene oxide a basis with fewer than 3 × 10 6 functions is large enough. Because the resulting basis has no exploitable structure we use a mapping to evaluate the matrix-vector products required to use an iterative eigensolver. The expanded basis is compared to bases obtained from pre-determined pruning condition. Similar calculations are presented for molecules with 3, 4, 5, and 6 atoms. For the 6-atom molecule, CH 3 CH, the required expanded basis has about 106 000 functions and is about an order of magnitude smaller than bases made with a pre-determined pruning condition.

10 CFR Appendix C to Part 73 - Nuclear Power Plant Safeguards Contingency Plans

Code of Federal Regulations, 2011 CFR

2011-01-01

... command and delegation of authority as these apply to safeguards contingencies. b. Physical Layout—(i..., up to and including the design basis threat of radiological sabotage. The goals of licensee.... Perceived Danger—Consistent with the design basis threat specified in § 73.1(a)(1), licensees shall identify...

18 CFR 1317.550 - Sex as a bona fide occupational qualification.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 2 2014-04-01 2014-04-01 false Sex as a bona fide... VALLEY AUTHORITY NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Employment in Education Programs or...

18 CFR 1317.550 - Sex as a bona fide occupational qualification.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Sex as a bona fide... VALLEY AUTHORITY NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Employment in Education Programs or...

18 CFR 1317.550 - Sex as a bona fide occupational qualification.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Sex as a bona fide... VALLEY AUTHORITY NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Employment in Education Programs or...

18 CFR 1317.550 - Sex as a bona fide occupational qualification.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 2 2013-04-01 2012-04-01 true Sex as a bona fide... VALLEY AUTHORITY NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Employment in Education Programs or...

18 CFR 1317.550 - Sex as a bona fide occupational qualification.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 2 2012-04-01 2012-04-01 false Sex as a bona fide... VALLEY AUTHORITY NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Employment in Education Programs or...

42 CFR 1003.102 - Basis for civil money penalties and assessments.

Code of Federal Regulations, 2010 CFR

2010-10-01

... AND HUMAN SERVICES OIG AUTHORITIES CIVIL MONEY PENALTIES, ASSESSMENTS AND EXCLUSIONS § 1003.102 Basis... provided as claimed, including a claim that is part of a pattern or practice of claims based on codes that... of the amount permitted to be charged; (iii) An agreement to be a participating physician or supplier...

[The methodological basis of expert assessment of unfavourable outcomes of the stomatological treatment in the framework of civil law proceedings].

PubMed

Pigolkin, Iu I; Murzova, T V; Mirzoev, Kh M

2011-01-01

The authors discuss peculiarities of the performance of forensic medical expertise in the cases of unfavourable outcomes of the stomatological treatment. The methodological basis of expert assessment has been created to be applied in situations related to the unfavourable outcomes of dental care.

18 CFR 1317.455 - Textbooks and curricular material.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Textbooks and curricular material. 1317.455 Section 1317.455 Conservation of Power and Water Resources TENNESSEE VALLEY AUTHORITY NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis o...

31 CFR 545.514 - Payments for services rendered by the Taliban to aircraft.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) SANCTIONS REGULATIONS Licenses, Authorizations and Statements of Licensing Policy § 545.514 Payments for services rendered by the Taliban to aircraft. (a) Specific licenses may be issued on a case-by-case basis.... (b) Specific licenses may be issued on a case-by-case basis for the exportation, reexportation, sale...

Twenty-One Reasons to Care about the Psychological Basis of Ownership

ERIC Educational Resources Information Center

Friedman, Ori; Ross, Hildy

2011-01-01

Within psychology, most aspects of ownership have received scant attention or have been overlooked completely. In this chapter, the authors outline 21 reasons why it will be important (and interesting) to understand the psychological basis of ownership of property, including its developmental origins: (1) Daily life; (2) A human universal, and…

Competency-based medical education and continuing professional development: A conceptualization for change.

PubMed

Lockyer, Jocelyn; Bursey, Ford; Richardson, Denyse; Frank, Jason R; Snell, Linda; Campbell, Craig

2017-06-01

Competency-based medical education (CBME) is as important in continuing professional development (CPD) as at any other stage of a physician's career. Principles of CBME have the potential to revolutionize CPD. Transitioning to CBME-based CPD will require a cultural change to gain commitment from physicians, their employers and institutions, CPD providers, professional organizations, and medical regulators. It will require learning to be aligned with professional and workplace standards. Practitioners will need to develop the expertise to systematically examine their own clinical performance data, identify performance improvement opportunities and possibilities, and develop a plan to address areas of concern. Health care facilities and systems will need to produce data on a regular basis and to develop and train CPD educators who can work with physician groups. Stakeholders, such as medical regulatory authorities who are responsible for licensing physicians and other standard-setting bodies that credential and develop maintenance-of-certification systems, will need to change their paradigm of competency enhancement through CPD.

An evolutionarily conserved gene family encodes proton-selective ion channels.

PubMed

Tu, Yu-Hsiang; Cooper, Alexander J; Teng, Bochuan; Chang, Rui B; Artiga, Daniel J; Turner, Heather N; Mulhall, Eric M; Ye, Wenlei; Smith, Andrew D; Liman, Emily R

2018-03-02

Ion channels form the basis for cellular electrical signaling. Despite the scores of genetically identified ion channels selective for other monatomic ions, only one type of proton-selective ion channel has been found in eukaryotic cells. By comparative transcriptome analysis of mouse taste receptor cells, we identified Otopetrin1 (OTOP1), a protein required for development of gravity-sensing otoconia in the vestibular system, as forming a proton-selective ion channel. We found that murine OTOP1 is enriched in acid-detecting taste receptor cells and is required for their zinc-sensitive proton conductance. Two related murine genes, Otop2 and Otop3 , and a Drosophila ortholog also encode proton channels. Evolutionary conservation of the gene family and its widespread tissue distribution suggest a broad role for proton channels in physiology and pathophysiology. Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

Guiding principles of safety as a basis for developing a pharmaceutical safety culture.

PubMed

Edwards, Brian; Olsen, Axel K; Whalen, Matthew D; Gold, Marla J

2007-05-01

Despite the best efforts of industry and regulatory authorities, the trust of society in the process of medicine development and communication of pharmaceutical risk has ebbed away. In response the US government has called for a culture of compliance while the EU regulators talk of a 'culture of scientific excellence'. However, one of the fundamental problems hindering progress to rebuilding trust based on a pharmaceutical safety culture is the lack of agreement and transparency between all stakeholders as to what is meant by a 'Safety of Medicines'. For that reason, we propose 'Guiding Principles of Safety for Pharmaceuticals' are developed analogous to the way that Chemical Safety has been tackled. A logical starting point would be to examine the Principles outlined by the US Institute of Medicine although we acknowledge that these Principles require further extensive debate and definition. Nevertheless, the Principles should take centre stage in the reform of pharmaceutical development required to restore society's trust.

Phosphoethanolamine cellulose: A naturally produced chemically modified cellulose.

PubMed

Thongsomboon, Wiriya; Serra, Diego O; Possling, Alexandra; Hadjineophytou, Chris; Hengge, Regine; Cegelski, Lynette

2018-01-19

Cellulose is a major contributor to the chemical and mechanical properties of plants and assumes structural roles in bacterial communities termed biofilms. We find that Escherichia coli produces chemically modified cellulose that is required for extracellular matrix assembly and biofilm architecture. Solid-state nuclear magnetic resonance spectroscopy of the intact and insoluble material elucidates the zwitterionic phosphoethanolamine modification that had evaded detection by conventional methods. Installation of the phosphoethanolamine group requires BcsG, a proposed phosphoethanolamine transferase, with biofilm-promoting cyclic diguanylate monophosphate input through a BcsE-BcsF-BcsG transmembrane signaling pathway. The bcsEFG operon is present in many bacteria, including Salmonella species, that also produce the modified cellulose. The discovery of phosphoethanolamine cellulose and the genetic and molecular basis for its production offers opportunities to modulate its production in bacteria and inspires efforts to biosynthetically engineer alternatively modified cellulosic materials. Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

An approach for management of geometry data

NASA Technical Reports Server (NTRS)

Dube, R. P.; Herron, G. J.; Schweitzer, J. E.; Warkentine, E. R.

1980-01-01

The strategies for managing Integrated Programs for Aerospace Design (IPAD) computer-based geometry are described. The computer model of geometry is the basis for communication, manipulation, and analysis of shape information. IPAD's data base system makes this information available to all authorized departments in a company. A discussion of the data structures and algorithms required to support geometry in IPIP (IPAD's data base management system) is presented. Through the use of IPIP's data definition language, the structure of the geometry components is defined. The data manipulation language is the vehicle by which a user defines an instance of the geometry. The manipulation language also allows a user to edit, query, and manage the geometry. The selection of canonical forms is a very important part of the IPAD geometry. IPAD has a canonical form for each entity and provides transformations to alternate forms; in particular, IPAD will provide a transformation to the ANSI standard. The DBMS schemas required to support IPAD geometry are explained.

Ordinance No. 054/PRG/SGG/87 on conditions of entry and stay in the Republic of Guinea, 22 July 1987.

PubMed

1989-01-01

An ordinance passed on July 22, 1987, governs the entry and residence of foreigners in Guinea. Passports are required for everyone but citizens of Guinea, and entry visas are necessary unless a person is in transit on a ship or airplane or is a citizen of a country which has a reciprocity agreement with Guinea. The entry visa, which is valid for 3 months, is gained by submitting a written request, proof of financial means, a return ticket or security deposit, and 2 photographs. The request may be granted or denies without explanation. Further entry requirements are a valid medical certificate and, if employed in Guinea, an approved employment contract. A transit visa is required of foreigners staying for no more than 5 days, unless they stay n areas designated by competent authorities. A temporary stay visa (renewable once) is required for foreigners who are staying from 5-90 days; they, like all foreigners in Guinea, must have a return ticket or means to leave. Foreigners who wish to stay in Guinea after expiration of their 90-day visa (except accompanied minors, citizens of certain countries, and diplomats) must obtain an extended stay visa, a residence permit, and an allied card. Experts working for the government of Guinea on a longterm basis need an expert resident identity card. Foreigners who wish to reside in Guinea must obtain a foreign resident card or alien card. Refugees and stateless persons must acquire a political refugee or stateless person identification card. To obtain a residence permit, foreigners must have entered Guinea, legally, paid visa and permit taxes, and have an extended stay visa, a certificate of recent physical examination, a work permit, and an employment contract. This permit may be renewed or replaced if lost. An alien card must be obtained by foreigners over the age of fifteen who work in Guinea and want to establish residence; this is issued after the foreigner has paid a tax and gotten an extended stay visa. Foreigners are permitted to move freely in the country, except in places designated by policy or security forces. Holders of alien cards or work permits must notify authorities if they change their address. Landlords, in turn, must notify authorities if they have foreigners as tenants. A foreign resident care and work permit are required in order to secure employment. In general, travelers and temporary residents are not allowed to hold a job. Employers who hire a foreigner must notify the National Employment Office and Immigration authorities. A foreigner's stay may be terminated by public authorities at any time. Those who help a foreigner enter, move through, or stay in the country illegally can be punished.

Medical Data Architecture Project Status

NASA Technical Reports Server (NTRS)

Krihak, M.; Middour, C.; Lindsey, A.; Marker, N.; Wolfe, S.; Winther, S.; Ronzano, K.; Bolles, D.; Toscano, W.; Shaw, T.

2017-01-01

The Medical Data Architecture (MDA) project supports the Exploration Medical Capability (ExMC) risk to minimize or reduce the risk of adverse health outcomes and decrements in performance due to in-flight medical capabilities on human exploration missions. To mitigate this risk, the ExMC MDA project addresses the technical limitations identified in ExMC Gap Med 07: We do not have the capability to comprehensively process medically-relevant information to support medical operations during exploration missions. This gap identifies that the current International Space Station (ISS) medical data management includes a combination of data collection and distribution methods that are minimally integrated with on-board medical devices and systems. Furthermore, there are variety of data sources and methods of data collection. For an exploration mission, the seamless management of such data will enable an increasingly autonomous crew than the current ISS paradigm. The MDA will develop capabilities that support automated data collection, and the necessary functionality and challenges in executing a self-contained medical system that approaches crew health care delivery without assistance from ground support. To attain this goal, the first year of the MDA project focused on reducing technical risk, developing documentation and instituting iterative development processes that established the basis for the first version of MDA software (or Test Bed 1). Test Bed 1 is based on a nominal operations scenario authored by the ExMC Element Scientist. This narrative was decomposed into a Concept of Operations that formed the basis for Test Bed 1 requirements. These requirements were successfully vetted through the MDA Test Bed 1 System Requirements Review, which permitted the MDA project to begin software code development and component integration. This paper highlights the MDA objectives, development processes, and accomplishments, and identifies the fiscal year 2017 milestones and deliverables in the upcoming year.

Rejoinder to Lemberger

ERIC Educational Resources Information Center

Hansen, James T.

2012-01-01

Lemberger (2012) argues that the author (Hansen, 2012) has no basis for recommending differential weightings or priorities to humanism and science, because those ideologies are only meaningful as they are subjectively interpreted within the counseling encounter. The author responds that their positions are completely compatible, but his focus was…

12 CFR 567.11 - Reservation of authority.

Code of Federal Regulations, 2011 CFR

2011-01-01

... part. (c)(1) Reservation of authority. Notwithstanding the definitions of core and supplementary... capital instrument constitutes or may constitute core or supplementary capital, and may permit one or more... capital instrument as core or supplementary capital, permanently or on a temporary basis, for the purposes...

30 CFR 1229.109 - Reimbursement for costs incurred by a State under the delegation of authority.

Code of Federal Regulations, 2011 CFR

2011-07-01

... under the delegation of authority. (a) The Department of the Interior (DOI) shall reimburse the State... DOI and will provide the DOI, on a quarterly basis, a summary of costs incurred for which the State is...

Process Metallurgy an Enabler of Resource Efficiency: Linking Product Design to Metallurgy in Product Centric Recycling

NASA Astrophysics Data System (ADS)

Reuter, Markus; van Schaik, Antoinette

In this paper the link between process metallurgy, classical minerals processing, product centric recycling and urban/landfill mining is discussed. The depth that has to be achieved in urban mining and recycling must glean from the wealth of theoretical knowledge and insight that have been developed in the past in minerals and metallurgical processing. This background learns that recycling demands a product centric approach, which considers simultaneously the multi-material interactions in man-made complex `minerals'. Fast innovation in recycling and urban mining can be achieved by further evolving from this well developed basis, evolving the techniques and tools that have been developed over the years. This basis has already been used for many years to design, operate and control industrial plants for metal production. This has been the basis for Design for Recycling rules for End-of-Life products. Using, among others, the UNEP Metal Recycling report as a basis (authors are respectively Lead and Main authors of report), it is demonstrated that a common theoretical basis as developed in metallurgy and minerals processing can help much to level the playing field between primary processing, secondary processing, recycling, and urban/landfill mining and product design hence enhancing resource efficiency. Thus various scales of detail link product design with metallurgical process design and its fundamentals.

'S.W.' and C.G. Jung: mediumship, psychiatry and serial exemplarity.

PubMed

Shamdasani, Sonu

2015-09-01

On the basis of unpublished materials, this essay reconstructs Jung's seances with his cousin, Helene Preiswerk, which formed the basis of his 1902 medical dissertation, The Psychology and Pathology of so-called Occult Phenomena. It separates out Jung's contemporaneous approach to the mediumistic phenomena she exhibited from his subsequent sceptical psychological reworking of the case. It traces the reception of the work and its significance for his own self-experimentation from 1913 onwards. Finally, it reconstructs the manner in which Jung continually returned to his first model and reframed it as an exemplar of his developing theories. © The Author(s) 2015.

The power of simplification: Operator interface with the AP1000{sup R} during design-basis and beyond design-basis events

DOE Office of Scientific and Technical Information (OSTI.GOV)

Williams, M. G.; Mouser, M. R.; Simon, J. B.

2012-07-01

The AP1000{sup R} plant is an 1100-MWe pressurized water reactor with passive safety features and extensive plant simplifications that enhance construction, operation, maintenance, safety and cost. The passive safety features are designed to function without safety-grade support systems such as component cooling water, service water, compressed air or HVAC. The AP1000 passive safety features achieve and maintain safe shutdown in case of a design-basis accident for 72 hours without need for operator action, meeting the expectations provided in the European Utility Requirements and the Utility Requirement Document for passive plants. Limited operator actions may be required to maintain safe conditionsmore » in the spent fuel pool (SFP) via passive means. This safety approach therefore minimizes the reliance on operator action for accident mitigation, and this paper examines the operator interaction with the Human-System Interface (HSI) as the severity of an accident increases from an anticipated transient to a design basis accident and finally, to a beyond-design-basis event. The AP1000 Control Room design provides an extremely effective environment for addressing the first 72 hours of design-basis events and transients, providing ease of information dissemination and minimal reliance upon operator actions. Symptom-based procedures including Emergency Operating Procedures (EOPs), Abnormal Operating Procedures (AOPs) and Alarm Response Procedures (ARPs) are used to mitigate design basis transients and accidents. Use of the Computerized Procedure System (CPS) aids the operators during mitigation of the event. The CPS provides cues and direction to the operators as the event progresses. If the event becomes progressively worse or lasts longer than 72 hours, and depending upon the nature of failures that may have occurred, minimal operator actions may be required outside of the control room in areas that have been designed to be accessible using components that have been designed to be reliable in these conditions. The primary goal of any such actions is to maintain or refill the passive inventory available to cool the core, containment and spent fuel pool in the safety-related and seismically qualified Passive Containment Cooling Water Storage Tank (PCCWST). The seismically-qualified, ground-mounted Passive Containment Cooling Ancillary Water Storage Tank (PCCAWST) is also available for this function as appropriate. The primary effect of these actions would be to increase the coping time for the AP1000 during design basis events, as well as events such as those described above, from 72 hours without operator intervention to 7 days with minimal operator actions. These Operator actions necessary to protect the health and safety of the public are addressed in the Post-72 Hour procedures, as well as some EOPs, AOPs, ARPs and the Severe Accident Management Guidelines (SAMGs). Should the event continue to become more severe and plant conditions degrade further with indications of inadequate core cooling, the SAMGs provide guidance for strategies to address these hypothetical severe accident conditions. The AP1000 SAMG diagnoses and actions are prioritized to first utilize the AP1000 features that are expected to retain a damaged core inside the reactor vessel. Only one strategy is undertaken at any time. This strategy will be followed and its effectiveness evaluated before other strategies are undertaken. This is a key feature of both the symptom-oriented AP1000 EOPs and the AP1000 SAMGs which maximizes the probability of retaining a damaged core inside the reactor vessel and containment while minimizing the chances for confusion and human errors during implementation. The AP1000 SAMGs are simple and straight-forward and have been developed with considerable input from human factors and plant operations experts. Most importantly, and different from severe accident management strategies for other plants, the AP1000 SAMGs do not require diagnosis of the location of the core (i.e., whether reactor vessel failure has occurred). This is a fundamental consequence of the AP1000 In-Vessel Retention approach, which allows severe accident management to be based on fundamental principles (e.g. provide coolant as close as possible to the core) that do not change during a specific event. This eliminates the need for one of the more difficult diagnostic requirements, since reactor vessel failure does not directly relate to any measurable plant parameter, and differs from other designs in that an engineered failure of the pressure vessel' (e.g. core catcher) is never required. (authors)« less

Addressing the Tension Between Strong Perimeter Control an Usability

NASA Technical Reports Server (NTRS)

Hinke, Thomas H.; Kolano, Paul Z.; Keller, Chris

2006-01-01

This paper describes a strong perimeter control system for a general purpose processing system, with the perimeter control system taking significant steps to address usability issues, thus mitigating the tension between strong perimeter protection and usability. A secure front end enforces two-factor authentication for all interactive access to an enclave that contains a large supercomputer and various associated systems, with each requiring their own authentication. Usability is addressed through a design in which the user has to perform two-factor authentication at the secure front end in order to gain access to the enclave, while an agent transparently performs public key authentication as needed to authenticate to specific systems within the enclave. The paper then describes a proxy system that allows users to transfer files into the enclave under script control, when the user is not present to perform two-factor authentication. This uses a pre-authorization approach based on public key technology, which is still strongly tied to both two-factor authentication and strict control over where files can be transferred on the target system. Finally the paper describes an approach to support network applications and systems such as grids or parallel file transfer protocols that require the use of many ports through the perimeter. The paper describes a least privilege approach that dynamically opens ports on a host-specific, if-authorized, as-needed, just-in-time basis.

49 CFR 25.535 - Effect of state or local law or other requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Employment in Education Programs or Activities Prohibited § 25.535 Effect... or other requirement that imposes prohibitions or limits upon employment of members of one sex that...

34 CFR 104.10 - Effect of state or local law or other requirements and effect of employment opportunities.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Department of Education OFFICE FOR CIVIL RIGHTS, DEPARTMENT OF EDUCATION NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE General Provisions § 104.10... or other requirement that, on the basis of handicap, imposes prohibitions or limits upon the...

34 CFR 104.10 - Effect of state or local law or other requirements and effect of employment opportunities.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Department of Education OFFICE FOR CIVIL RIGHTS, DEPARTMENT OF EDUCATION NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE General Provisions § 104.10... or other requirement that, on the basis of handicap, imposes prohibitions or limits upon the...

34 CFR 104.10 - Effect of state or local law or other requirements and effect of employment opportunities.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Department of Education OFFICE FOR CIVIL RIGHTS, DEPARTMENT OF EDUCATION NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE General Provisions § 104.10... or other requirement that, on the basis of handicap, imposes prohibitions or limits upon the...

34 CFR 104.10 - Effect of state or local law or other requirements and effect of employment opportunities.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Department of Education OFFICE FOR CIVIL RIGHTS, DEPARTMENT OF EDUCATION NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE General Provisions § 104.10... or other requirement that, on the basis of handicap, imposes prohibitions or limits upon the...

34 CFR 104.10 - Effect of state or local law or other requirements and effect of employment opportunities.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Department of Education OFFICE FOR CIVIL RIGHTS, DEPARTMENT OF EDUCATION NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE General Provisions § 104.10... or other requirement that, on the basis of handicap, imposes prohibitions or limits upon the...

14 CFR 1251.109 - Effect of State or local law or other requirements and effect of employment opportunities.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AERONAUTICS AND SPACE ADMINISTRATION NONDISCRIMINATION ON BASIS OF HANDICAP General Provisions § 1251.109... or other requirement that, on the basis of handicap, imposes prohibitions or limits upon the eligibility of qualified handicapped persons to receive services or to practice any occupation or profession...

14 CFR 1251.109 - Effect of State or local law or other requirements and effect of employment opportunities.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AERONAUTICS AND SPACE ADMINISTRATION NONDISCRIMINATION ON BASIS OF HANDICAP General Provisions § 1251.109... or other requirement that, on the basis of handicap, imposes prohibitions or limits upon the eligibility of qualified handicapped persons to receive services or to practice any occupation or profession...

14 CFR 1251.109 - Effect of State or local law or other requirements and effect of employment opportunities.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AERONAUTICS AND SPACE ADMINISTRATION NONDISCRIMINATION ON BASIS OF HANDICAP General Provisions § 1251.109... or other requirement that, on the basis of handicap, imposes prohibitions or limits upon the eligibility of qualified handicapped persons to receive services or to practice any occupation or profession...

14 CFR 1251.109 - Effect of State or local law or other requirements and effect of employment opportunities.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AERONAUTICS AND SPACE ADMINISTRATION NONDISCRIMINATION ON BASIS OF HANDICAP General Provisions § 1251.109... or other requirement that, on the basis of handicap, imposes prohibitions or limits upon the eligibility of qualified handicapped persons to receive services or to practice any occupation or profession...

14 CFR § 1251.109 - Effect of State or local law or other requirements and effect of employment opportunities.

Code of Federal Regulations, 2014 CFR

2014-01-01

... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION NONDISCRIMINATION ON BASIS OF HANDICAP General Provisions... local law or other requirement that, on the basis of handicap, imposes prohibitions or limits upon the eligibility of qualified handicapped persons to receive services or to practice any occupation or profession...

42 CFR 483.150 - Statutory basis; Deemed meeting or waiver of requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... CARE FACILITIES Requirements That Must Be Met by States and State Agencies: Nurse Aide Training and Competency Evaluation, and Paid Feeding Assistants § 483.150 Statutory basis; Deemed meeting or waiver of... 1919(f)(2) of the Act, which establish standards for training nurse-aides and for evaluating their...

42 CFR 483.150 - Statutory basis; Deemed meeting or waiver of requirements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... CARE FACILITIES Requirements That Must Be Met by States and State Agencies: Nurse Aide Training and Competency Evaluation, and Paid Feeding Assistants § 483.150 Statutory basis; Deemed meeting or waiver of... 1919(f)(2) of the Act, which establish standards for training nurse-aides and for evaluating their...

42 CFR 483.150 - Statutory basis; Deemed meeting or waiver of requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... CARE FACILITIES Requirements That Must Be Met by States and State Agencies: Nurse Aide Training and Competency Evaluation, and Paid Feeding Assistants § 483.150 Statutory basis; Deemed meeting or waiver of... 1919(f)(2) of the Act, which establish standards for training nurse-aides and for evaluating their...

42 CFR 483.150 - Statutory basis; Deemed meeting or waiver of requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... CARE FACILITIES Requirements That Must Be Met by States and State Agencies: Nurse Aide Training and Competency Evaluation, and Paid Feeding Assistants § 483.150 Statutory basis; Deemed meeting or waiver of... 1919(f)(2) of the Act, which establish standards for training nurse-aides and for evaluating their...

"Plate cherry picking": a novel semi-sequential screening paradigm for cheaper, faster, information-rich compound selection.

PubMed

Crisman, Thomas J; Jenkins, Jeremy L; Parker, Christian N; Hill, W Adam G; Bender, Andreas; Deng, Zhan; Nettles, James H; Davies, John W; Glick, Meir

2007-04-01

This work describes a novel semi-sequential technique for in silico enhancement of high-throughput screening (HTS) experiments now employed at Novartis. It is used in situations in which the size of the screen is limited by the readout (e.g., high-content screens) or the amount of reagents or tools (proteins or cells) available. By performing computational chemical diversity selection on a per plate basis (instead of a per compound basis), 25% of the 1,000,000-compound screening was optimized for general initial HTS. Statistical models are then generated from target-specific primary results (percentage inhibition data) to drive the cherry picking and testing from the entire collection. Using retrospective analysis of 11 HTS campaigns, the authors show that this method would have captured on average two thirds of the active compounds (IC(50) < 10 microM) and three fourths of the active Murcko scaffolds while decreasing screening expenditure by nearly 75%. This result is true for a wide variety of targets, including G-protein-coupled receptors, chemokine receptors, kinases, metalloproteinases, pathway screens, and protein-protein interactions. Unlike time-consuming "classic" sequential approaches that require multiple iterations of cherry picking, testing, and building statistical models, here individual compounds are cherry picked just once, based directly on primary screening data. Strikingly, the authors demonstrate that models built from primary data are as robust as models built from IC(50) data. This is true for all HTS campaigns analyzed, which represent a wide variety of target classes and assay types.

40 CFR 5.405 - Housing.

Code of Federal Regulations, 2010 CFR

2010-07-01

... of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex..., on the basis of sex, apply different rules or regulations, impose different fees or requirements, or...

40 CFR 5.405 - Housing.

Code of Federal Regulations, 2013 CFR

2013-07-01

... of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex..., on the basis of sex, apply different rules or regulations, impose different fees or requirements, or...

Developing Competency in Payroll Procedures

ERIC Educational Resources Information Center

Jackson, Allen L.

1975-01-01

The author describes a sequence of units that provides for competency in payroll procedures. The units could be the basis for a four to six week minicourse and are adaptable, so that the student, upon completion, will be able to apply his learning to any payroll procedures system. (Author/AJ)

Energy saving in WWTP: Daily benchmarking under uncertainty and data availability limitations.

PubMed

Torregrossa, D; Schutz, G; Cornelissen, A; Hernández-Sancho, F; Hansen, J

2016-07-01

Efficient management of Waste Water Treatment Plants (WWTPs) can produce significant environmental and economic benefits. Energy benchmarking can be used to compare WWTPs, identify targets and use these to improve their performance. Different authors have performed benchmark analysis on monthly or yearly basis but their approaches suffer from a time lag between an event, its detection, interpretation and potential actions. The availability of on-line measurement data on many WWTPs should theoretically enable the decrease of the management response time by daily benchmarking. Unfortunately this approach is often impossible because of limited data availability. This paper proposes a methodology to perform a daily benchmark analysis under database limitations. The methodology has been applied to the Energy Online System (EOS) developed in the framework of the project "INNERS" (INNovative Energy Recovery Strategies in the urban water cycle). EOS calculates a set of Key Performance Indicators (KPIs) for the evaluation of energy and process performances. In EOS, the energy KPIs take in consideration the pollutant load in order to enable the comparison between different plants. For example, EOS does not analyse the energy consumption but the energy consumption on pollutant load. This approach enables the comparison of performances for plants with different loads or for a single plant under different load conditions. The energy consumption is measured by on-line sensors, while the pollutant load is measured in the laboratory approximately every 14 days. Consequently, the unavailability of the water quality parameters is the limiting factor in calculating energy KPIs. In this paper, in order to overcome this limitation, the authors have developed a methodology to estimate the required parameters and manage the uncertainty in the estimation. By coupling the parameter estimation with an interval based benchmark approach, the authors propose an effective, fast and reproducible way to manage infrequent inlet measurements. Its use enables benchmarking on a daily basis and prepares the ground for further investigation. Copyright © 2016 Elsevier Inc. All rights reserved.

Data and Information Management: Essential Basis for Sustainable Urban Management and Development

NASA Astrophysics Data System (ADS)

Geerders, P.; Kokke, E.

2011-08-01

Management of the urban environment and urban development require well organized data and information as a basis for decision making, planning and policy development. Such data and information needs to be up-to-date, reliable and complete, and moreover be available at the time of need. The latter is especially relevant in the case of disasters such as fires, flooding, earthquakes and volcanic eruptions. Current and future impacts of the on-going climate changes increase the need for geo-referenced data and information on environment, biodiversity and public health, in support of preparation, protection, mitigation and reconstruction. It is important that urban authorities devote more attention and resources to data and information management in order to be able to cope with the present and future challenges of ever growing cities with increasing impacts on their surroundings, and moreover to deal with the impacts of environment and biodiversity on the cities, their population and economies. SOD, Woerden has a long and successful track record of certified training and education in the field of data and information management for authorities, including urban government. The courses provided by SOD cover a wide range of subjects from metadata and digitizing, to enterprise content management and geo-information management. While focused on the Netherlands, SOD also has initiated similar training opportunities in Belgium and Surinam, and efforts are under way in other countries. P. Geerders Consultancy has considerable experience as a consultant and trainer in the field of methods and technologies for the provision of information in support of decision-making, planning and policy development related to integrated management and sustainable development of natural resources. Besides in various countries of Europe, he has worked in Latin America and the Caribbean region. Since several years, P. Geerders works as a freelance teacher with SOD. The paper presents a vision on training and education of urban authorities in information handling and management.

A Basis for Determining the Adequacy of Evaluation Designs

ERIC Educational Resources Information Center

Sanders, James R.; Nafziger, Dean N.

2011-01-01

The purpose of this paper is to provide a basis for judging the adequacy of evaluation plans or, as they are commonly called, evaluation designs. The authors assume that using the procedures suggested in this paper to determine the adequacy of evaluation designs in advance of actually conducting evaluations will lead to better evaluation designs,…

Primal Splitting as a Basis for Emotional and Cognitive Development in Children

ERIC Educational Resources Information Center

Caccia, Ornella

2009-01-01

This article discusses the importance of good primal splitting as the basis for the child's emotional and cognitive development. A theoretical introduction analyses the possible pathologies of primal splitting, as they were first pointed out by Melanie Klein and then by some post-Kleinian authors, in particular Donald Meltzer. This is followed by…

24 CFR 5.903 - What special authority is there to obtain access to criminal records?

Code of Federal Regulations, 2010 CFR

2010-04-01

... criminal conviction records, may be a basis for applicant screening, lease enforcement or eviction, as... determination whether such criminal conviction records may be a basis for applicant screening, lease enforcement...) Screening. If you are an owner of covered housing, you may request that the PHA in the jurisdiction of the...

The Organic Etiology of Infantile Autism: Myth or Fact?

ERIC Educational Resources Information Center

Sanua, Victor D.

The author reviews theories and research on the etiology of infantile autism, specifically regarding its organic basis. He cites controversies over its organic vs. environmental basis and over the family's impact on autism. Quotes from such theoriests as L. Kanner, B. Bettleheim, and B. Rimland are presented along with E. R. Ritvo and M. Coleman.…

Insurance Coverage Policies for Pharmacogenomic and Multi-Gene Testing for Cancer.

PubMed

Lu, Christine Y; Loomer, Stephanie; Ceccarelli, Rachel; Mazor, Kathleen M; Sabin, James; Clayton, Ellen Wright; Ginsburg, Geoffrey S; Wu, Ann Chen

2018-05-16

Insurance coverage policies are a major determinant of patient access to genomic tests. The objective of this study was to examine differences in coverage policies for guideline-recommended pharmacogenomic tests that inform cancer treatment. We analyzed coverage policies from eight Medicare contractors and 10 private payers for 23 biomarkers (e.g., HER2 and EGFR ) and multi-gene tests. We extracted policy coverage and criteria, prior authorization requirements, and an evidence basis for coverage. We reviewed professional society guidelines and their recommendations for use of pharmacogenomic tests. Coverage for KRAS , EGFR , and BRAF tests were common across Medicare contractors and private payers, but few policies covered PML/RARA , CD25 , or G6PD . Thirteen payers cover multi-gene tests for nonsmall lung cancer, citing emerging clinical recommendations. Coverage policies for single and multi-gene tests for cancer treatments are consistent among Medicare contractors despite the lack of national coverage determinations. In contrast, coverage for these tests varied across private payers. Patient access to tests is governed by prior authorization among eight private payers. Substantial variations in how payers address guideline-recommended pharmacogenomic tests and the common use of prior authorization underscore the need for additional studies of the effects of coverage variation on cancer care and patient outcomes.

Preliminary Authorization Basis Documentation for the Proposed Bio Safety Level 3 (BSl-3) Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Altenbach, T J; Nguyen, S N

2003-09-20

Lawrence Livermore National Laboratory (LLNL) is proposing to construct a biosafety level (BSL-3) facility at Site 200 in Livermore, California. Biosafety level 3 (BSL-3) is a designation assigned by the Centers for Disease Control and Prevention (CDC) and National Institutes Health (NIH) for handling infectious organisms based on the specific microorganisms and associated operations. Biosafety levels range from BSL-1 (lowest hazard) to BSL-4 (highest hazard). Details about the BSL-3 criteria are described in the Center of Disease Control and Prevention (CDC)/National Institutes of Health (NIH)'s publication ''Biosafety Microbiological and Biomedical Laboratories'' (BMBL), 4th edition (CDC 1999): The BSL-3 facility willmore » be built in accordance with the required BMBL guidelines. This Preliminary Authorization Basis Documentation (PABD) for the proposed BSL-3 facility has been prepared in accordance with the current contractual requirements at LLNL. This includes the LLNL Environment, Safety, and Health Manual (ES&H Manual) and applicable Work Smart Standards, including the biosafety standards, such as the aforementioned BMBL and the NIH Guidelines for Research Involving Recombinant DNA Molecules: The proposed BSL-3 facility is a 1,100 ft{sup 2}, one-story permanent prefabricated facility, which will have three individual BSL-3 laboratory rooms (one of which is an animal biosafety level-3 [ABSL-3] laboratory to handle rodents), a mechanical room, clothes-change and shower rooms, and small storage space (Figure 3.1). The BSL-3 facility will be designed and operated accordance with guidelines for BSL-3 laboratories established by the CDC and the NIH. No radiological, high explosives, fissile, or propellant material will be used or stored in the proposed BSL-3 facility. The BSL-3 facility will be used to develop scientific tools to identify and understand the pathogens of medical, environmental, and forensic importance. Microorganisms that are to be handled in this facility will be limited in quantity, type and form in accordance with the BMBL requirements and approval by the Institutional Biosafety Committee (IBC). The proposed facility will have the unique capability within DOE/NNSA to perform aerosol studies to include challenges to rodents using infectious agents or biologically derived toxins (biotoxins). These types of aerosol studies will be strictly confined in a Class II Type B biosafety cabinet.« less

Archaerhodopsin Selectively and Reversibly Silences Synaptic Transmission through Altered pH.

PubMed

El-Gaby, Mohamady; Zhang, Yu; Wolf, Konstantin; Schwiening, Christof J; Paulsen, Ole; Shipton, Olivia A

2016-08-23

Tools that allow acute and selective silencing of synaptic transmission in vivo would be invaluable for understanding the synaptic basis of specific behaviors. Here, we show that presynaptic expression of the proton pump archaerhodopsin enables robust, selective, and reversible optogenetic synaptic silencing with rapid onset and offset. Two-photon fluorescence imaging revealed that this effect is accompanied by a transient increase in pH restricted to archaerhodopsin-expressing boutons. Crucially, clamping intracellular pH abolished synaptic silencing without affecting the archaerhodopsin-mediated hyperpolarizing current, indicating that changes in pH mediate the synaptic silencing effect. To verify the utility of this technique, we used trial-limited, archaerhodopsin-mediated silencing to uncover a requirement for CA3-CA1 synapses whose afferents originate from the left CA3, but not those from the right CA3, for performance on a long-term memory task. These results highlight optogenetic, pH-mediated silencing of synaptic transmission as a spatiotemporally selective approach to dissecting synaptic function in behaving animals. Copyright © 2016 The Author(s). Published by Elsevier Inc. All rights reserved.

Secrecy as embodied practice: beyond the confessional imperative.

PubMed

Hardon, Anita; Posel, Deborah

2012-01-01

This introduction to this special issue of Culture, Health & Sexuality aims to intervene critically in debates in public health about sexual rights and ways of de-stigmatising HIV/AIDS, in which silence and secrets are seen to undermine well-being and perpetuate stigma. It presents key insights from collaborative studies on HIV/AIDS and youth sexual health, arguing that advocates of disclosure and sexual rights need to think more contextually and tactically in promoting truth-telling. The authors aim to enhance current thinking on secrecy, which examines it primarily as a social practice, by emphasising the centrality of the body and the experience of embodiment in the making and unmaking of secrets. To understand secrecy as embodied practice requires understanding how it simultaneously involves the body as subject - as the basis from which we experience the world - and the body as object - that can be actively manipulated, silenced and 'done'. The authors show how tensions emerge when bodies reveal reproductive mishaps and describe how the dissonances are resolved through a variety of silencing practices. The paper ends by discussing the implications of these insights for sexual-health programmes.

[Development and innovation of traditional Chinese medicine processing discipline and Chinese herbal pieces industry].

PubMed

Xiao, Yong-Qing; Li, Li; Liu, Ying; Ma, Yin-Lian; Yu, Ding-Rong

2016-01-01

To elucidate the key issues in the development and innovation of traditional Chinese medicine processing discipline and Chinese herbal pieces industry Chinese herbal pieces industry. According to the author's accumulated experience over years and demand of the development of the Chinese herbal pieces industry, the key issues in the development and innovation on the Chinese herbal pieces industry were summarized. According to the author, the traditional Chinese medicine processing discipline shall focus on a application basis research. The development of this discipline should be closely related to the development of Chinese herbal pieces. The traditional Chinese medicine processing discipline can be improved and its results can be transformed only if this discipline were correlated with the Chinese herbal pieces industry, matched with the development of the Chinese herbal pieces industry, and solved the problems in the development on the Chinese herbal pieces industry. The development of traditional Chinese medicine processing discipline and the Chinese herbal pieces industry also requires scientific researchers to make constant innovations, realize the specialty of the researches, and innovate based on inheritance. Copyright© by the Chinese Pharmaceutical Association.

The Ethics of Clinical Care and the Ethics of Clinical Research: Yin and Yang.

PubMed

Kowalski, Charles J; Hutchinson, Raymond J; Mrdjenovich, Adam J

2017-02-01

The Belmont Report's distinction between research and the practice of accepted therapy has led various authors to suggest that these purportedly distinct activities should be governed by different ethical principles. We consider some of the ethical consequences of attempts to separate the two and conclude that separation fails along ontological, ethical, and epistemological dimensions. Clinical practice and clinical research, as with yin and yang, can be thought of as complementary forces interacting to form a dynamic system in which the whole exceeds the sum of its parts. Just as effective clinical practice cannot exist without clinical research, meaningful clinical research requires the context of clinical practice. We defend this thesis by triangulation, that is, by outlining how multiple investigators have reached this conclusion on the basis of varied theoretical and applied approaches. More confidence can be placed in a result if different methods/viewpoints have led to that result. © The Author 2017. Published by Oxford University Press, on behalf of the Journal of Medicine and Philosophy Inc. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Characterizing Adhesion between a Micropatterned Surface and a Soft Synthetic Tissue.

PubMed

Kern, Madalyn D; Qi, Yuan; Long, Rong; Rentschler, Mark E

2017-01-31

The work of adhesion and work of separation are characteristic properties of a contact interface that describe the amount of energy per unit area required to adhere or separate two contacting substrates, respectively. In this work, the authors present experimental and data analysis procedures that allow the contact interface between a soft synthetic tissue and a smooth or micropatterned poly(dimethylsiloxane) (PDMS) substrate to be characterized in terms of these characteristic parameters. Because of physical geometry limitations, the experimental contact geometry chosen for this study differs from conventional test geometries. Therefore, the authors used finite element modeling to develop correction factors specific to the experimental contact geometry used in this work. A work of adhesion was directly extracted from experimental data while the work of separation was estimated on the basis of experimental results. These values are compared to other theoretical calculations for validation. The results of this work indicate that the micropatterned PDMS substrate significantly decreases both the work of adhesion and work of separation as compared to a smooth PDMS substrate when in contact with a soft synthetic tissue substrate.

[Psychiatry of the future: an overview of foreign scientists opinions of the position of psychiatry in the modern world].

PubMed

Makushkin, Ye V; Oskolkova, S N; Fastovtsov, G A

2017-01-01

First part of this review (Chapter 1) demonstrates an ambiguous attitude toward psychiatry among professionals and in society in recent decades. The articles of supporters and opponents of psychiatry are also quoted. The authors describe the dynamics of the reflection of psychopathology in the main widely accepted classifications and manuals. Critical and negative opinions regarding the DSM-5, due to its role in the 'medicalization' processes, for the movement 'World Mental Health', are mentioned. The history of antipsychiatry movement and its results for psychiatry and society are analyzed as well. An analysis of the articles on the scientific basis of psychiatry and its intersections with other sciences is presented. Several examples of studies on brain networks in correlation with clinical data, which may have possible implications for the future, are quoted. The authors call for the 'cure for dichotomy' between mind and brain before treatment of the patient. According to the analysis of available data, this problem seems too hard to be solved, as it requires theological knowledge, of which we probably have not enough knowledge.

Postural Control During Cascade Ball Juggling: Effects of Expertise and Base of Support.

PubMed

Rodrigues, Sérgio T; Polastri, Paula F; Gotardi, Gisele C; Aguiar, Stefane A; Mesaros, Marcelo R; Pestana, Mayara B; Barbieri, Fabio A

2016-08-01

Cascade ball juggling is a complex perceptual motor skill which requires efficient postural stabilization. The aim of this study was to investigate effects of experience (expert and intermediate groups) and foot distance (wide and narrow stances) on body sway of jugglers during three ball cascade juggling. A total of 10 expert jugglers and 11 intermediate jugglers participated in this study. Participants stood barefoot on the force plate (some participants wore a gaze tracking system), with feet maintained in wide and narrow conditions and performed three 40-seconds trials of the three-ball juggling task. Dependent variables were sway mean velocity, amplitude, mean frequency, number of ball cycles, fixation number, mean duration and its variability, and area of gaze displacement. Two-way analyses of variance with factors for group and condition were conducted. Experts' body sway was characterized by lower velocity and smaller amplitude as compared to intermediate group. Interestingly, the more challenging (narrow) basis of support caused significant attenuation in body sway only for the intermediate group. These data suggest that expertise in cascade juggling was associated with refined postural control. © The Author(s) 2016.

Cognitive load and task condition in event- and time-based prospective memory: an experimental investigation.

PubMed

Khan, Azizuddin; Sharma, Narendra K; Dixit, Shikha

2008-09-01

Prospective memory is memory for the realization of delayed intention. Researchers distinguish 2 kinds of prospective memory: event- and time-based (G. O. Einstein & M. A. McDaniel, 1990). Taking that distinction into account, the present authors explored participants' comparative performance under event- and time-based tasks. In an experimental study of 80 participants, the authors investigated the roles of cognitive load and task condition in prospective memory. Cognitive load (low vs. high) and task condition (event- vs. time-based task) were the independent variables. Accuracy in prospective memory was the dependent variable. Results showed significant differential effects under event- and time-based tasks. However, the effect of cognitive load was more detrimental in time-based prospective memory. Results also revealed that time monitoring is critical in successful performance of time estimation and so in time-based prospective memory. Similarly, participants' better performance on the event-based prospective memory task showed that they acted on the basis of environment cues. Event-based prospective memory was environmentally cued; time-based prospective memory required self-initiation.

Maternal Inheritance of a Recessive RBP4 Defect in Canine Congenital Eye Disease.

PubMed

Kaukonen, Maria; Woods, Sean; Ahonen, Saija; Lemberg, Seppo; Hellman, Maarit; Hytönen, Marjo K; Permi, Perttu; Glaser, Tom; Lohi, Hannes

2018-05-29

Maternally skewed transmission of traits has been associated with genomic imprinting and oocyte-derived mRNA. We report canine congenital eye malformations, caused by an amino acid deletion (K12del) near the N terminus of retinol-binding protein (RBP4). The disease is only expressed when both dam and offspring are deletion homozygotes. RBP carries vitamin A (retinol) from hepatic stores to peripheral tissues, including the placenta and developing eye, where it is required to synthesize retinoic acid. Gestational vitamin A deficiency is a known risk factor for ocular birth defects. The K12del mutation disrupts RBP folding in vivo, decreasing its secretion from hepatocytes to serum. The maternal penetrance effect arises from an impairment in the sequential transfer of retinol across the placenta, via RBP encoded by maternal and fetal genomes. Our results demonstrate a mode of recessive maternal inheritance, with a physiological basis, and they extend previous observations on dominant-negative RBP4 alleles in humans. Copyright © 2018 The Author(s). Published by Elsevier Inc. All rights reserved.

45 CFR 86.32 - Housing.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Department of Health and Human Services GENERAL ADMINISTRATION NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex..., on the basis of sex, apply different rules or regulations, impose different fees or requirements, or...

45 CFR 86.32 - Housing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex..., on the basis of sex, apply different rules or regulations, impose different fees or requirements, or...

45 CFR 86.32 - Housing.

Code of Federal Regulations, 2012 CFR

2012-10-01

... DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex..., on the basis of sex, apply different rules or regulations, impose different fees or requirements, or...

43 CFR 41.405 - Housing.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Lands: Interior Office of the Secretary of the Interior NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex..., on the basis of sex, apply different rules or regulations, impose different fees or requirements, or...

Basis sets for the calculation of core-electron binding energies

NASA Astrophysics Data System (ADS)

Hanson-Heine, Magnus W. D.; George, Michael W.; Besley, Nicholas A.

2018-05-01

Core-electron binding energies (CEBEs) computed within a Δ self-consistent field approach require large basis sets to achieve convergence with respect to the basis set limit. It is shown that supplementing a basis set with basis functions from the corresponding basis set for the element with the next highest nuclear charge (Z + 1) provides basis sets that give CEBEs close to the basis set limit. This simple procedure provides relatively small basis sets that are well suited for calculations where the description of a core-ionised state is important, such as time-dependent density functional theory calculations of X-ray emission spectroscopy.

Course Formats for Teaching Management Consulting

ERIC Educational Resources Information Center

Schmidt, Sascha L.; Richter, Ansgar

2006-01-01

In this article, the authors introduce 3 different course formats for teaching management consulting at the university. On the basis of data from self-evaluation questionnaires from 159 students, the authors analyze effectiveness of these course designs in raising the self-confidence of participants to cope with the kind of tasks typically faced…

Why Novice Teachers Leave

ERIC Educational Resources Information Center

Robertson, Mark

2006-01-01

The author conducted a study of reasons why novice teachers become disenchanted with the administrative support in their schools. Using the ideas of Rosenholtz and Simpson (1990) as a basis for his research, the author designed and administered a survey to 53 novice teachers and 15 building principals regarding the factors that influence novice…

Using Achievement Goals and Interest to Predict Learning in Physical Education

ERIC Educational Resources Information Center

Shen, Bo; Chen, Ang; Guan, Jianmin

2007-01-01

On the basis of an integrated theoretical approach to achievement motivation, the authors designed this study to investigate the potential influence of mastery goal, performance-approach and avoidance-approach goals, individual interest, and situational interest on students' learning in a physical education softball unit. The authors collected and…

25 CFR 163.37 - Forest management research.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 1 2011-04-01 2011-04-01 false Forest management research. 163.37 Section 163.37 Indians... Management and Operations § 163.37 Forest management research. The Secretary, with the consent of the authorized Indian representatives' is authorized to perform forestry research activities to improve the basis...

25 CFR 163.37 - Forest management research.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 1 2012-04-01 2011-04-01 true Forest management research. 163.37 Section 163.37 Indians... Management and Operations § 163.37 Forest management research. The Secretary, with the consent of the authorized Indian representatives' is authorized to perform forestry research activities to improve the basis...

25 CFR 163.37 - Forest management research.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Forest management research. 163.37 Section 163.37 Indians... Management and Operations § 163.37 Forest management research. The Secretary, with the consent of the authorized Indian representatives' is authorized to perform forestry research activities to improve the basis...

Rejoinder to V. Suthakaran

ERIC Educational Resources Information Center

Hansen, James T.

2012-01-01

V. Suthakaran (2012) uses cognitive-experiential self-theory as the basis for his argument that the humanities and science should have equal ideological status in the counseling profession. The author disagrees with this basic thesis and some of the related theoretical points that V. Suthakaran makes. However, the author agrees that the humanities…

The Money-Creation Model: Graphic Illustration

ERIC Educational Resources Information Center

Lai, Ching-chong; Chang, Juin-jen; Kao, Ming-ruey

2004-01-01

The authors propose a pedagogical apparatus embodying a solid micro-foundation with emphasis on the public's choice between currency and demand deposits being an optimal decision. On the basis of the pedagogical exposition, the authors explain how money supply is related to the combined behaviors of the central bank, commercial banks, and the…

27 CFR 41.81 - Taxpayment.

Code of Federal Regulations, 2010 CFR

2010-04-01

... tax must be paid on the basis of a return on the customs form or by authorized electronic transmission... customs form or authorized electronic transmission the following internal revenue tax information. (1) For... rate of tax, and the tax due. (4) For cigars. The importer will show: (i) The number imported under...

26 CFR 1.6662-0 - Table of contents.

Code of Federal Regulations, 2011 CFR

2011-04-01

...) Determination of whether substantial authority is present. (i) Evaluation of authorities. (ii) Nature of...) Property with a value or adjusted basis of zero. (h) Pass-through entities. (1) In general. (2) Example. (i) [Reserved] (j) Transactions between persons described in section 482 and net section 482 transfer price...

26 CFR 1.6662-0 - Table of contents.

Code of Federal Regulations, 2012 CFR

2012-04-01

...) Determination of whether substantial authority is present. (i) Evaluation of authorities. (ii) Nature of...) Property with a value or adjusted basis of zero. (h) Pass-through entities. (1) In general. (2) Example. (i) [Reserved] (j) Transactions between persons described in section 482 and net section 482 transfer price...

26 CFR 1.6662-0 - Table of contents.

Code of Federal Regulations, 2013 CFR

2013-04-01

...) Determination of whether substantial authority is present. (i) Evaluation of authorities. (ii) Nature of...) Property with a value or adjusted basis of zero. (h) Pass-through entities. (1) In general. (2) Example. (i) [Reserved] (j) Transactions between persons described in section 482 and net section 482 transfer price...

26 CFR 1.6662-0 - Table of contents.

Code of Federal Regulations, 2014 CFR

2014-04-01

...) Determination of whether substantial authority is present. (i) Evaluation of authorities. (ii) Nature of...) Property with a value or adjusted basis of zero. (h) Pass-through entities. (1) In general. (2) Example. (i) [Reserved] (j) Transactions between persons described in section 482 and net section 482 transfer price...

Authorizing the Foreign Language Students.

ERIC Educational Resources Information Center

Maxim, Hiram H.

1998-01-01

Reviews current practices in foreign-language teaching in light of Bourdieu's theories of language and power to show how failing to assess discursive intent prevents students from understanding strategic use of language. Bordieu's model is then proposed as the basis for pedagogy that authorizes students to use their existing cognitive skills in…

Innateness Claims in Psycholinguistics.

ERIC Educational Resources Information Center

Lamendella, John T.

While agreeing with psycholinguistic and neurolinguistic theories that suggest that innate language-related cognitive structures are the basis of language development, the author seeks to establish what it is that is innate and what is meant by innateness in the first place. The author considers the claims of psychological relevance made on behalf…

38 CFR 21.372 - Interregional transfer at government expense.

Code of Federal Regulations, 2011 CFR

2011-07-01

... AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Vocational Rehabilitation and Employment Under... social ties, and in which he or she plans to live following rehabilitation; (3) To report to an employer... because VA did not issue the necessary travel authorization on a timely basis. (Authority: 38 U.S.C. 111...

38 CFR 21.372 - Interregional transfer at government expense.

Code of Federal Regulations, 2014 CFR

2014-07-01

... AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Vocational Rehabilitation and Employment Under... social ties, and in which he or she plans to live following rehabilitation; (3) To report to an employer... because VA did not issue the necessary travel authorization on a timely basis. (Authority: 38 U.S.C. 111...

38 CFR 21.372 - Interregional transfer at government expense.

Code of Federal Regulations, 2013 CFR

2013-07-01

... AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Vocational Rehabilitation and Employment Under... social ties, and in which he or she plans to live following rehabilitation; (3) To report to an employer... because VA did not issue the necessary travel authorization on a timely basis. (Authority: 38 U.S.C. 111...

38 CFR 21.372 - Interregional transfer at government expense.

Code of Federal Regulations, 2010 CFR

2010-07-01

... AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Vocational Rehabilitation and Employment Under... social ties, and in which he or she plans to live following rehabilitation; (3) To report to an employer... because VA did not issue the necessary travel authorization on a timely basis. (Authority: 38 U.S.C. 111...

38 CFR 21.372 - Interregional transfer at government expense.

Code of Federal Regulations, 2012 CFR

2012-07-01

... AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Vocational Rehabilitation and Employment Under... social ties, and in which he or she plans to live following rehabilitation; (3) To report to an employer... because VA did not issue the necessary travel authorization on a timely basis. (Authority: 38 U.S.C. 111...

Academic Motivation in Children with Dyslexia

ERIC Educational Resources Information Center

Lodygowska, Ewa; Chec, Magdalena; Samochowiec, Agnieszka

2017-01-01

The authors' purpose was to determine which form of therapeutic aid may influence academic approach and avoidance motivation in children with dyslexia. There were 165 children with dyslexia assessed with the use of "I and my school" questionnaire. The authors considered the children's previous therapeutic experience and on its basis they…

7 CFR 1940.962 - Authority to transfer direct loan amounts.

Code of Federal Regulations, 2013 CFR

2013-01-01

... list. (2) Amounts transferred on a National basis. The amount of direct loan funds transferred in a FY... 7 Agriculture 13 2013-01-01 2013-01-01 false Authority to transfer direct loan amounts. 1940.962... SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT...

7 CFR 1940.962 - Authority to transfer direct loan amounts.

Code of Federal Regulations, 2011 CFR

2011-01-01

... list. (2) Amounts transferred on a National basis. The amount of direct loan funds transferred in a FY... 7 Agriculture 13 2011-01-01 2009-01-01 true Authority to transfer direct loan amounts. 1940.962... SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT...

7 CFR 1940.962 - Authority to transfer direct loan amounts.

Code of Federal Regulations, 2014 CFR

2014-01-01

... list. (2) Amounts transferred on a National basis. The amount of direct loan funds transferred in a FY... 7 Agriculture 13 2014-01-01 2013-01-01 true Authority to transfer direct loan amounts. 1940.962... SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT...

7 CFR 1940.962 - Authority to transfer direct loan amounts.

Code of Federal Regulations, 2012 CFR

2012-01-01

... list. (2) Amounts transferred on a National basis. The amount of direct loan funds transferred in a FY... 7 Agriculture 13 2012-01-01 2012-01-01 false Authority to transfer direct loan amounts. 1940.962... SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT...

7 CFR 1940.962 - Authority to transfer direct loan amounts.

Code of Federal Regulations, 2010 CFR

2010-01-01

... list. (2) Amounts transferred on a National basis. The amount of direct loan funds transferred in a FY... 7 Agriculture 13 2010-01-01 2009-01-01 true Authority to transfer direct loan amounts. 1940.962... SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY, DEPARTMENT...

EMC problems on board the remote sensing and communications satellites equipped with electric propulsions

NASA Astrophysics Data System (ADS)

Plokhikh, A.; Vazhenin, N.; Soganova, G.

Wide application of electric propulsions (EP) as attitude control and orbit correction thrusters for a numerous class of satellites (remote sensing and communications satellites including) imposes new problems before the developers in meeting the electromagnetic compatibility requirements on board these satellites. This is connected with the fact that any EP is a source of interference broad-band emission reaching, as a rule, frequency ranges used by on-board radio systems designed for remote sensing and communications. In this case, reliable joint operation should be secured for the highly sensitive on -board radio receiving systems and sensors of remote sensing systems on one hand and EP on the other. In view of this, analysis is rather actual for the influence of EP interference emission upon the parameters and characteristics of modern remote sensing and communications systems. Procedures and results of typical operating characteristics calculation for the radio systems with the presence of operating EP on board are discussed in the paper on the basis of systematic approach with the following characteristics being among them: signal-to-noise ratio, range, data transmission rate, error probability, etc. EP effect is taken into account by the statistical analysis for the results of joint influence of valid signal and interference produced by EP upon the quality indices of communication systems and paths of the sensors being the parts of remote sensing systems. Test data for the measured EP interference characteristics were used for qualitative assessments. All necessary measurements were made by authors on the basis of the test procedure developed by them for assessing self- em ission of EP under ground conditions that may be used as a base for the certification of such measurements. Analysis was made on the basis of test data obtained and calculation procedures developed by authors for the EP influence upon the qualitative characteristics of remote sensing and communications radio systems that revealed the presence of destructive effect resulting in substantial decrease in maximum range and data transmission rate, as well as reduction of sensitivity for the sensors of remote sensing systems. Recommendations are given on the basis of analysis made for the optimization of radio systems and calibration of their sensors at a presence of electric propulsions on board the satellites.

78 FR 61183 - Regulated Navigation Area; Reporting Requirements for Barges Loaded With Certain Dangerous...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-03

... under section 4(a) of the Administrative Procedure Act (APA) (5 U.S.C. 553(b)). This provision... publication. This temporary final rule, suspending the reporting requirements and thereby relieving the... effective the same date of its publication in the Federal Register. B. Basis and Purpose The legal basis for...

40 CFR 5.535 - Effect of state or local law or other requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Employment in Education Programs or Activities Prohibited § 5.535 Effect of... other requirement that imposes prohibitions or limits upon employment of members of one sex that are not...

Computer mapping of LANDSAT data for environmental applications

NASA Technical Reports Server (NTRS)

Rogers, R. H. (Principal Investigator); Mckeon, J. B.; Reed, L. E.; Schmidt, N. F.; Schecter, R. N.

1975-01-01

The author has identified the following significant results. Land cover overlays and maps produced from LANDSAT are providing information on existing land use and resources throughout the 208 study area. The overlays are being used to delineate drainage areas of a predominant land cover type. Information on cover type is also being combined with other pertinent data to develop estimates of sediment and nutrients flows from the drainage area. The LANDSAT inventory of present land cover together with population projects is providing a basis for developing maps of anticipated land use patterns required to evaluate impact on water quality which may result from these patterns. Overlays of forest types were useful for defining wildlife habitat and vegetational resources in the region. LANDSAT data and computer assisted interpretation was found to be a rapid cost effective procedure for inventorying land cover on a regional basis. The entire 208 inventory which include acquisition of ground truth, LANDSAT tapes, computer processing, and production of overlays and coded tapes was completed within a period of 2 months at a cost of about 0.6 cents per acre, a significant improvement in time and cost over conventional photointerpretation and mapping techniques.

45 CFR 618.310 - Recruitment.

Code of Federal Regulations, 2014 CFR

2014-10-01

... ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Admission and Recruitment Prohibited § 618.310 Recruitment. (a... basis of sex in the recruitment and admission of students. A recipient may be required to undertake...

10 CFR 1042.415 - Access to course offerings.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in... of sex, or require or refuse participation therein by any of its students on such basis, including...

10 CFR 1042.415 - Access to course offerings.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in... of sex, or require or refuse participation therein by any of its students on such basis, including...

10 CFR 1042.415 - Access to course offerings.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in... of sex, or require or refuse participation therein by any of its students on such basis, including...

10 CFR 1042.415 - Access to course offerings.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in... of sex, or require or refuse participation therein by any of its students on such basis, including...

Multiprocessor shared-memory information exchange

DOE Office of Scientific and Technical Information (OSTI.GOV)

Santoline, L.L.; Bowers, M.D.; Crew, A.W.

1989-02-01

In distributed microprocessor-based instrumentation and control systems, the inter-and intra-subsystem communication requirements ultimately form the basis for the overall system architecture. This paper describes a software protocol which addresses the intra-subsystem communications problem. Specifically the protocol allows for multiple processors to exchange information via a shared-memory interface. The authors primary goal is to provide a reliable means for information to be exchanged between central application processor boards (masters) and dedicated function processor boards (slaves) in a single computer chassis. The resultant Multiprocessor Shared-Memory Information Exchange (MSMIE) protocol, a standard master-slave shared-memory interface suitable for use in nuclear safety systems, ismore » designed to pass unidirectional buffers of information between the processors while providing a minimum, deterministic cycle time for this data exchange.« less

Unwritten rules: virtual bargaining underpins social interaction, culture, and society.

PubMed

Misyak, Jennifer B; Melkonyan, Tigran; Zeitoun, Hossam; Chater, Nick

2014-10-01

Many social interactions require humans to coordinate their behavior across a range of scales. However, aspects of intentional coordination remain puzzling from within several approaches in cognitive science. Sketching a new perspective, we propose that the complex behavioral patterns - or 'unwritten rules' - governing such coordination emerge from an ongoing process of 'virtual bargaining'. Social participants behave on the basis of what they would agree to do if they were explicitly to bargain, provided the agreement that would arise from such discussion is commonly known. Although intuitively simple, this interpretation has implications for understanding a broad spectrum of social, economic, and cultural phenomena (including joint action, team reasoning, communication, and language) that, we argue, depend fundamentally on the virtual bargains themselves. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

Codex Alimentarius: food quality and safety standards for international trade.

PubMed

Randell, A W; Whitehead, A J

1997-08-01

Since 1962, the Codex Alimentarius Commission (CAC) of the Food and Agriculture Organisation/World Health Organisation has been responsible for developing standards, guidelines and other recommendations on the quality and safety of food to protect the health of consumers and to ensure fair practices in food trade. The mission of the CAC remains relevant, but a number of factors have shown the need for new techniques to form the basis of food standards, the most important of which is risk analysis. The authors give a brief description of the role and work of the CAC and the efforts deployed by the Commission to respond to the challenges posed by new approaches to government regulation, harmonisation of national requirements based on international standards and the role of civil society.

[Research and development strategies in classical herbal formulae].

PubMed

Chen, Chang; Cheng, Jin-Tang; Liu, An

2017-05-01

As an outstanding representative of traditional Chinese medicine prescription, classical herbal formulae are the essence of traditional Chinese medicine great treasure. To support the development of classical herbal formulae, the state and relevant administrative departments have successively promulgated the relevant encouraged policies.But some key issues of classic herbal formulae in the development process have not reached a unified consensus and standard, and these problems were discussed in depth here.The authors discussed the registration requirements of classical herbal formulae, proposed the screening specific indicators of classical herbal formulae, determination basis of prescription and dosage,screening method of production process, and the basic principle of clinical localization, in order to bring out valuable opinions and provide a reference for classical herbal formulae development and policy formulation. Copyright© by the Chinese Pharmaceutical Association.

Researching the experience of kidney cancer patients.

PubMed

Taylor, K

2002-09-01

The author's personal experience as a kidney cancer patient, researcher and founder of a kidney cancer support group forms the basis for consideration of the challenges involved in researching patients' experiences. The researcher needs to understand the variability of those experiences in both clinical and psychological-emotional terms, and in relation to the personal, familial and social contexts of the patient. It is also essential to define the purpose of the research and to show how an understanding of personal experiences of cancer can be used to enhance the quality of care for cancer patients. The research encounter with a patient is also in some respects a therapeutic encounter requiring a considerable degree of sensitivity on the part of the researcher. The person-centred approach of Carl Rogers is of value in supporting such an encounter.

[On improvement of the mechanism for establishing and changing indicators of quality and food safety in the regulatory and legal acts of the Eurasian Economical Union].

PubMed

Arnautov, O V

2016-01-01

In accordance with the Treaty on the Eurasian Economic Union (EAEU) to ensure the sanitary and epidemiological welfare of the population within the Union, a coordinated policy in agreed policy in the sphere of application of sanitary measures is carried out. Sanitary measures are the obligatory requirements and procedures, including requirements for the final product, processing methods, production, transportation, storage and disposal, sampling procedures, methods of research (tests), risk assessment, the state registration, requirements for packaging directly aimed at ensuring the safety of products (goods) in order to protect human welfare, and they should be applied on the basis having a scientific explanation, and only to the extent that is necessary to protect human welfare. Sanitary measures applied within the Union should be based on international and regional standards, guidelines and (or) the recommendations, except when they based on appropriate scientific studies and explanations. In this case sanitary measures which could provide a higher level of sanitary protection are introduced. At present, the mechanism of the development, justification and approval of common sanitary and epidemiological requirements (ESR) and procedures of the Eurasian Economic Commission (the Commission) is not installed. The absence of a clear mechanism for the development, approval and implementation of the ESR to the products (goods) on the basis having a scientific explanation on the one hand could lead to the creation of unjustified barriers to foreign and mutual trade, on the other--to weaken the level of safety for human life and health of products (goods) placed on markets of the Union. In order to bring the regulatory legal acts of the Customs Union in accordance with the Treaty on the Eurasian Economic Union the Commission in cooperation with the competent authorities of the Member States in the field of sanitary and epidemiological welfare developed the project of Guidelines for development, approval, modification and application of common sanitary epidemiological and hygienic requirements and procedures (hereinafter--Guidelines) which is currently undergoing approval procedures. The project envisages that the Uniform sanitary requirements are established on the basis of scientific research, including the evaluation of the risk of harmful effects of the environment on the human factors, taking into consideration the analysis of international experience in order to harmonize common sanitary requirements with international standards, guidelines and (or) recommendations. Adoption of the draft Guidelines, as well as the application of common methodologies of risk assessment and the hygienic standardization in establishing and justifying safety performance of products (goods) in the Eurasian Economic Union allow quickly and transparently develop, validate, coordinate and approve the Uniform sanitary and epidemiological and hygienic requirements and procedures for sanitary inspection (control) of products (goods) and include them into technical regulations Union.

Clinical and radiographic success of mineral trioxide aggregate compared with formocresol as a pulpotomy treatment in primary molars: a systematic review and meta-analysis.

PubMed

Marghalani, Abdullah A; Omar, Samah; Chen, Jung-Wei

2014-07-01

The authors conducted a systematic review and meta-analysis to compare the long-term clinical and radiographic success of using mineral trioxide aggregate (MTA) and formocresol (FC) as a pulp-dressing material in pulpotomy treatment in primary molars. The authors searched MEDLINE, Thomson Reuters Web of Science and the Cochrane Central Register of Controlled Trials for randomized controlled trials (RCTs) published from Jan. 1, 1990, to May 9, 2013. For an RCT to be included, the authors required that the primary molars treated with a pulpotomy procedure must have received stainless steel crowns as a final restoration and that rubber dam isolation was used during treatment; that the pulp must have been vital as determined clinically by means of hemorrhage control with a cotton pellet; and that the RCT must have included a follow-up period of at least two years. For each included RCT, two authors assessed the risk of bias independently. The authors identified 20 trials and included five of them. A total of 377 primary molars were treated. The authors judged that none of the included RCTs had a low risk of bias. They noted no significant differences in clinical success (relative risk [RR] = 1.01; 95 percent confidence interval [CI], 0.98-1.05) and radiographic success (RR = 1.09; 95 percent CI, 0.97-1.21) for primary molars treated with MTA versus those treated with FC. On the basis of the limited evidence, pulpotomy procedures performed in primary molars involving the use of MTA or FC showed comparable clinical success rates.

A 'Global Reference' Comparator for Biosimilar Development.

PubMed

Webster, Christopher J; Woollett, Gillian R

2017-08-01

Major drug regulators have indicated in guidance their flexibility to accept some development data for biosimilars generated with reference product versions licensed outside their own jurisdictions, but most authorities require new bridging studies between these versions and the versions of them licensed locally. The costs of these studies are not trivial in absolute terms and, due to the multiplier effect of required repetition by each biosimilar sponsor, their collective costs are substantial. Yet versions of biologics licensed in different jurisdictions usually share the same development data, and any manufacturing changes between versions have been justified by a rigorous comparability process. The fact that a biosimilar is usually expected to be licensed in multiple jurisdictions, in each case as similar to the local reference product, confirms that minor analytical differences between versions of reference biologics are typically inconsequential for clinical outcomes and licensing. A greatly simplified basis for selecting a reference comparator, that does not require conducting new bridging studies, is proposed and justified based on the shared data of the reference product versions as well as the proof offered where biosimilars have already been approved. The relevance of this proposal to the interchangeability designation available in the US is discussed.

47 CFR 22.703 - Separate rural subscriber station authorization not required.

Code of Federal Regulations, 2010 CFR

2010-10-01

... or base station from which they receive service. ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Separate rural subscriber station authorization... subscriber station authorization not required. A separate authorization is not required for rural subscriber...

Systematization, condensed description, and prediction of sets of anion exchange extraction constants on the basis of their statistical treatment by computer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mezhov, E.A.; Reimarov, G.A.; Rubisov, V.N.

1987-05-01

On the basis of a statistical treatment of the entire set of published data on anion exchange extraction constants, the authors have refined and expanded the scale of the hydration parameters for the anions ..delta..G/sub hydr/ (the effective free energies of hydration for the anions). The authors have estimated the parameters ..delta..G for 93 anions and the coefficients % for 94 series of extraction systems, which are distinguished within each series only by the nature of the exchanging anions. The series are distinguished from one another by the nature of the cation extraction agent and the diluent.

Using Media as the Basis for a Social Issues Approach to Promoting Moral Literacy in University Teaching

ERIC Educational Resources Information Center

Normore, Anthony H.; Doscher, Stephanie Paul

2007-01-01

Purpose: The purpose of this research is to explore the use of media as the basis for a social issues approach to promoting moral literacy and effective teaching in educational leadership programs. Design/methodology/approach: Through a review of relevant literature, mass media sources, and observations, the authors use Starratt's framework of…

Organization of Physical Activities as a Precondition of Quality Development of Motor Abilities of Pre-School and School Children

ERIC Educational Resources Information Center

Markovic, Živorad; Kopas-Vukašinovic, Emina

2015-01-01

In their work authors consider the significance of the organization of physical activities for the development of abilities of pre-school and school children. Led by theoretical basis that physical development of children represents the basis of their whole development, and that "fine motor skills" are determined by the development of…

45 CFR 164.102 - Statutory basis.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Statutory basis. 164.102 Section 164.102 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES ADMINISTRATIVE DATA STANDARDS AND RELATED REQUIREMENTS SECURITY AND PRIVACY General Provisions § 164.102 Statutory basis. The provisions of this part are adopted...

45 CFR 164.102 - Statutory basis.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 1 2014-10-01 2014-10-01 false Statutory basis. 164.102 Section 164.102 Public Welfare Department of Health and Human Services ADMINISTRATIVE DATA STANDARDS AND RELATED REQUIREMENTS SECURITY AND PRIVACY General Provisions § 164.102 Statutory basis. The provisions of this part are adopted...

45 CFR 164.102 - Statutory basis.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 1 2011-10-01 2011-10-01 false Statutory basis. 164.102 Section 164.102 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES ADMINISTRATIVE DATA STANDARDS AND RELATED REQUIREMENTS SECURITY AND PRIVACY General Provisions § 164.102 Statutory basis. The provisions of this part are adopted...

49 CFR 25.415 - Access to course offerings.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Transportation Office of the Secretary of Transportation NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in... of sex, or require or refuse participation therein by any of its students on such basis, including...

10 CFR 5.415 - Access to course offerings.

Code of Federal Regulations, 2013 CFR

2013-01-01

... NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or... otherwise carry out any of its education program or activity separately on the basis of sex, or require or...

24 CFR 3.415 - Access to course offerings.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Development NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 3... any of its education program or activity separately on the basis of sex, or require or refuse...

49 CFR 25.415 - Access to course offerings.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Transportation Office of the Secretary of Transportation NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in... of sex, or require or refuse participation therein by any of its students on such basis, including...

32 CFR 196.415 - Access to course offerings.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) MISCELLANEOUS NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 196... any of its education program or activity separately on the basis of sex, or require or refuse...

24 CFR 3.415 - Access to course offerings.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Development NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 3... any of its education program or activity separately on the basis of sex, or require or refuse...

32 CFR 196.415 - Access to course offerings.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) MISCELLANEOUS NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 196... any of its education program or activity separately on the basis of sex, or require or refuse...

38 CFR 23.415 - Access to course offerings.

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 23... any of its education program or activity separately on the basis of sex, or require or refuse...

49 CFR 25.415 - Access to course offerings.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Transportation Office of the Secretary of Transportation NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in... of sex, or require or refuse participation therein by any of its students on such basis, including...

32 CFR 196.415 - Access to course offerings.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) MISCELLANEOUS NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 196... any of its education program or activity separately on the basis of sex, or require or refuse...

10 CFR 5.415 - Access to course offerings.

Code of Federal Regulations, 2011 CFR

2011-01-01

... NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or... otherwise carry out any of its education program or activity separately on the basis of sex, or require or...

45 CFR 2555.415 - Access to course offerings.

Code of Federal Regulations, 2011 CFR

2011-10-01

... COMMUNITY SERVICE NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities... carry out any of its education program or activity separately on the basis of sex, or require or refuse...

24 CFR 3.415 - Access to course offerings.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Development NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 3... any of its education program or activity separately on the basis of sex, or require or refuse...

45 CFR 2555.415 - Access to course offerings.

Code of Federal Regulations, 2012 CFR

2012-10-01

... COMMUNITY SERVICE NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities... carry out any of its education program or activity separately on the basis of sex, or require or refuse...

24 CFR 3.415 - Access to course offerings.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Development NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 3... any of its education program or activity separately on the basis of sex, or require or refuse...

10 CFR 5.415 - Access to course offerings.

Code of Federal Regulations, 2014 CFR

2014-01-01

... NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or... otherwise carry out any of its education program or activity separately on the basis of sex, or require or...

45 CFR 2555.415 - Access to course offerings.

Code of Federal Regulations, 2013 CFR

2013-10-01

... COMMUNITY SERVICE NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities... carry out any of its education program or activity separately on the basis of sex, or require or refuse...

38 CFR 23.415 - Access to course offerings.

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 23... any of its education program or activity separately on the basis of sex, or require or refuse...

49 CFR 25.415 - Access to course offerings.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Transportation Office of the Secretary of Transportation NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in... of sex, or require or refuse participation therein by any of its students on such basis, including...

45 CFR 2555.415 - Access to course offerings.

Code of Federal Regulations, 2014 CFR

2014-10-01

... COMMUNITY SERVICE NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities... carry out any of its education program or activity separately on the basis of sex, or require or refuse...

38 CFR 23.415 - Access to course offerings.

Code of Federal Regulations, 2011 CFR

2011-07-01

... (CONTINUED) NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 23... any of its education program or activity separately on the basis of sex, or require or refuse...

10 CFR 5.415 - Access to course offerings.

Code of Federal Regulations, 2012 CFR

2012-01-01

... NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or... otherwise carry out any of its education program or activity separately on the basis of sex, or require or...

32 CFR 196.415 - Access to course offerings.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) MISCELLANEOUS NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 196... any of its education program or activity separately on the basis of sex, or require or refuse...

38 CFR 23.415 - Access to course offerings.

Code of Federal Regulations, 2012 CFR

2012-07-01

... (CONTINUED) NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 23... any of its education program or activity separately on the basis of sex, or require or refuse...

47 CFR 4.1 - Scope, basis and purpose.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false Scope, basis and purpose. 4.1 Section 4.1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL DISRUPTIONS TO COMMUNICATIONS General § 4.1 Scope, basis and purpose. In this part, the Federal Communications Commission is setting forth requirements...

47 CFR 4.1 - Scope, basis and purpose.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 47 Telecommunication 1 2012-10-01 2012-10-01 false Scope, basis and purpose. 4.1 Section 4.1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL DISRUPTIONS TO COMMUNICATIONS General § 4.1 Scope, basis and purpose. In this part, the Federal Communications Commission is setting forth requirements...

Preventing HIV infection: educating the general public.

PubMed

Kroger, F

1991-01-01

This essay discusses the rationale for targeting HIV prevention programs to the general public, as opposed to focusing strictly on high-risk populations. The author first considers varying definitions of the term "general public," then explains the goal of general public education programs. Additionally, the author lays down the theoretical foundations of general audience education programs and weights related research findings. Finally, he offers recommendations for future practice. Noting the complex socioecological elements involved in health behavior, the author argues in favor of a broad definition for the general public. This broad outlook allows programs to still target high-risk population while not bypassing low-risk persons, who are sometimes treated as irrelevant because they do not contribute to excess morbidity or mortality. When it comes to HIV educational programs for the general public, their goals should be to instruct the public on how the virus is transmitted, to allay unfounded fears, and to increase the level of support for AIDS prevention and control. Such a program would require a theoretical basis drawn from multiple sources: health education, health communication, clinical and social psychology, and social marketing. The author concludes by proving recommendations designed to reinforce existing programs: 1) strengthen efforts to ensure that all people are educated about HIV and to encourage people to treat AIDS patients with compassion; 2) continue to explore for the most effective communication channels; 3) strengthen the communication infrastructure for those who are disenfranchised from health education; and 4) strengthen evaluation efforts of health communication programs.

76 FR 26787 - Short Sale Reporting Study Required by Dodd-Frank Act Section 417(a)(2)

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-09

... benefits and costs be if this real time reporting information were to be made public on a delayed basis..., benefits, and costs be if this real time reporting information were to be made public on a delayed basis... feasibility, benefits, and costs of requiring reporting in real time, either publicly or, in the alternative...

26 CFR 1.521-1 - Farmers' cooperative marketing and purchasing associations; requirements for exemption under...

Code of Federal Regulations, 2013 CFR

2013-04-01

... thereunder. For instance, cooperative dairy companies which are engaged in collecting milk and disposing of... the producers upon the basis of either the quantity or the value of milk or of butterfat in the milk... anyother way than on such a proportionate basis, the association does not meet the requirements of the Code...

26 CFR 1.521-1 - Farmers' cooperative marketing and purchasing associations; requirements for exemption under...

Code of Federal Regulations, 2011 CFR

2011-04-01

... thereunder. For instance, cooperative dairy companies which are engaged in collecting milk and disposing of... the producers upon the basis of either the quantity or the value of milk or of butterfat in the milk... anyother way than on such a proportionate basis, the association does not meet the requirements of the Code...

26 CFR 1.521-1 - Farmers' cooperative marketing and purchasing associations; requirements for exemption under...

Code of Federal Regulations, 2014 CFR

2014-04-01

... thereunder. For instance, cooperative dairy companies which are engaged in collecting milk and disposing of... the producers upon the basis of either the quantity or the value of milk or of butterfat in the milk... anyother way than on such a proportionate basis, the association does not meet the requirements of the Code...

26 CFR 1.521-1 - Farmers' cooperative marketing and purchasing associations; requirements for exemption under...

Code of Federal Regulations, 2012 CFR

2012-04-01

... thereunder. For instance, cooperative dairy companies which are engaged in collecting milk and disposing of... the producers upon the basis of either the quantity or the value of milk or of butterfat in the milk... anyother way than on such a proportionate basis, the association does not meet the requirements of the Code...

40 CFR Table 6 to Subpart Dddd of... - Initial Compliance Demonstrations for Work Practice Requirements

Code of Federal Regulations, 2010 CFR

2010-07-01

... moisture content less than or equal to 30 percent (by weight, dry basis) AND operate with an inlet dryer... dryer” AND you have a record of the inlet moisture content and inlet dryer temperature (as required in... an inlet moisture content of less than or equal to 25 percent (by weight, dry basis) You meet the...

40 CFR Table 6 to Subpart Dddd of... - Initial Compliance Demonstrations for Work Practice Requirements

Code of Federal Regulations, 2011 CFR

2011-07-01

... moisture content less than or equal to 30 percent (by weight, dry basis) AND operate with an inlet dryer... dryer” AND you have a record of the inlet moisture content and inlet dryer temperature (as required in... an inlet moisture content of less than or equal to 25 percent (by weight, dry basis) You meet the...

26 CFR 1.614-6 - Rules applicable to basis, holding period, and abandonment losses where mineral interests have...

Code of Federal Regulations, 2010 CFR

2010-04-01

...: Unadjusted basis Adjustments under Section 1016 No. 1 $25,000 $27,000 No. 2 18,000 10,000 No. 3 15,000 4,000... 1016 to the effective date of aggregation. Thereafter, the adjustments to basis required by section 1016 shall apply to the total adjusted basis of the aggregated property for all purposes of subtitle A...

26 CFR 1.614-6 - Rules applicable to basis, holding period, and abandonment losses where mineral interests have...

Code of Federal Regulations, 2011 CFR

2011-04-01

...: Unadjusted basis Adjustments under Section 1016 No. 1 $25,000 $27,000 No. 2 18,000 10,000 No. 3 15,000 4,000... 1016 to the effective date of aggregation. Thereafter, the adjustments to basis required by section 1016 shall apply to the total adjusted basis of the aggregated property for all purposes of subtitle A...

76 FR 62048 - ConocoPhillips Company; Application for Blanket Authorization To Export Previously Imported...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-06

... Authorization To Export Previously Imported Liquefied Natural Gas on a Short-Term Basis AGENCY: Office of Fossil Energy, DOE. ACTION: Notice of application. SUMMARY: The Office of Fossil Energy (FE) of the Department...), Office of Natural Gas Regulatory Activities, Office of Fossil Energy, P.O. Box 44375, Washington, DC...

78 FR 32697 - Delegation to the Assistant Secretary for Administration of Procurement Functions and Authorities

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-31

... herein, to the extent authorized by law, to any qualified employee of the Department of State. 4. The... performance of acquisition activities and acquisition programs of the Department, evaluating the performance of those programs on the basis of applicable performance measurements, and advising the Secretary...

The varieties of depressive experience: diagnosing mood disorders.

PubMed

Ghaemi, S Nassir; Vöhringer, Paul A; Vergne, Derick E

2012-03-01

Biopsychosocial eclecticism has led, the authors believe, to a simplistic acceptance of a unitary view of MDD with little scientific solidity. The authors propose a return to careful psychopathology as the basis of all nosology, which has led to identifying four main types of depressive illness, and a method-based, existential approach to understanding depression.

78 FR 43810 - State of Kansas; Authorization of State Hazardous Waste Management Program

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-22

... seeking authorization for the National Environmental Performance Track Program (April 22, 2004, 69 FR... terminated the National Environmental Performance Track Program. (c) Kansas has not adopted the optional... or more hazardous waste containers are stored, on a monthly basis. (c) At 28-31-262a(f)(2)(B)(i) and...

Verb Comprehension and Use in Children and Adults with Down Syndrome

ERIC Educational Resources Information Center

Michael, Sarah E.; Ratner, Nan Bernstein; Newman, Rochelle

2012-01-01

Purpose: Expressive syntax is a particular area of difficulty for individuals with Down syndrome (DS). In order to better understand the basis for sentence formulation deficits often observed in children and adults with DS, the authors explored the use and comprehension of verbs differing in argument structure. Method: The authors examined verb…

77 FR 12302 - Information Collection Being Reviewed by the Federal Communications Commission

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-29

... necessary for the proper performance of the functions of the Commission, including whether the information...). This transmitter must not cause harmful interference to stations authorized to operate on a primary... device: ``This device may not interfere with stations authorized to operate on a primary basis in the 413...

Beliefs about Knowledge, Knowing, and Learning: Differences across Knowledge Types in Physics

ERIC Educational Resources Information Center

Muis, Krista R.; Gierus, Bogusia

2014-01-01

The authors examined whether students' epistemic and learning beliefs varied across different knowledge types in physics. On the basis of various beliefs frameworks, the authors predicted that individuals' beliefs would vary within a domain across the same content when presented conceptually versus procedurally. Participants were 81 high…

38 CFR 3.802 - Medal of Honor.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., Compensation, and Dependency and Indemnity Compensation Special Benefits § 3.802 Medal of Honor. (a) The... certificate issued in which the right of the person named in the certificate to the special pension is set forth. The special pension will be authorized on the basis of such certification. (Authority: 38 U.S.C...

38 CFR 36.4352 - Authority to close loans on the automatic basis.

Code of Federal Regulations, 2011 CFR

2011-07-01

...(s) of warehouse lines of credit must be submitted to VA and the applicant must agree that VA may... supporting credit data have been developed on its behalf by a duly authorized agent. (11) Probation. Lenders.... (2) Processing annual lender data. The VA regional office having jurisdiction for the lender's...

29 CFR 2590.701-1 - Basis and scope.

Code of Federal Regulations, 2011 CFR

2011-07-01

... creditable coverage. (4) Special enrollment periods. (5) Prohibition against discrimination on the basis of health factors. (6) Additional requirements prohibiting discrimination based on genetic information. (7...

42 CFR 436.1100 - Basis and scope.

Code of Federal Regulations, 2010 CFR

2010-10-01

...) MEDICAL ASSISTANCE PROGRAMS ELIGIBILITY IN GUAM, PUERTO RICO, AND THE VIRGIN ISLANDS Option for Coverage of Special Groups § 436.1100 Basis and scope. (a) Statutory basis. Section 1920A of the Act allows... requirements for providing medical assistance to special groups who are not eligible for Medicaid as...

45 CFR 86.34 - Access to course offerings.

Code of Federal Regulations, 2010 CFR

2010-10-01

... BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 86.34 Access to course offerings... activity separately on the basis of sex, or require or refuse participation therein by any of its students...

45 CFR 86.34 - Access to course offerings.

Code of Federal Regulations, 2012 CFR

2012-10-01

... BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 86.34 Access to course offerings... activity separately on the basis of sex, or require or refuse participation therein by any of its students...

45 CFR 618.415 - Access to course offerings.

Code of Federal Regulations, 2014 CFR

2014-10-01

... NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 618.415 Access to course... or activity separately on the basis of sex, or require or refuse participation therein by any of its...

29 CFR 36.415 - Access to course offerings.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Office of the Secretary of Labor NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or... otherwise carry out any of its education program or activity separately on the basis of sex, or require or...

29 CFR 36.415 - Access to course offerings.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Office of the Secretary of Labor NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or... otherwise carry out any of its education program or activity separately on the basis of sex, or require or...

40 CFR 5.415 - Access to course offerings.

Code of Federal Regulations, 2010 CFR

2010-07-01

... BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 5.415 Access to course offerings... activity separately on the basis of sex, or require or refuse participation therein by any of its students...

18 CFR 1317.415 - Access to course offerings.

Code of Federal Regulations, 2012 CFR

2012-04-01

... NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 1317.415 Access to course... or activity separately on the basis of sex, or require or refuse participation therein by any of its...

13 CFR 113.415 - Access to course offerings.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Nondiscrimination on the Basis of Sex in Education Programs or Activities Receiving Federal Financial Assistance Discrimination on the Basis of Sex in Education Programs Or Activities Prohibited § 113.415 Access to course... or activity separately on the basis of sex, or require or refuse participation therein by any of its...

31 CFR 28.415 - Access to course offerings.

Code of Federal Regulations, 2014 CFR

2014-07-01

... THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 28.415 Access to course... or activity separately on the basis of sex, or require or refuse participation therein by any of its...